Are Discrepancies in RANS Modeled Reynolds Stresses Random?
Xiao, Heng; Wang, Jian-xun; Paterson, Eric G
2016-01-01
In the turbulence modeling community, significant efforts have been made to quantify the uncertainties in the Reynolds-Averaged Navier--Stokes (RANS) models and to improve their predictive capabilities. Of crucial importance in these efforts is the understanding of the discrepancies in the RANS modeled Reynolds stresses. However, to what extent these discrepancies can be predicted or whether they are completely random remains a fundamental open question. In this work we used a machine learning algorithm based on random forest regression to predict the discrepancies. The success of the regression--prediction procedure indicates that, to a large extent, the discrepancies in the modeled Reynolds stresses can be explained by the mean flow feature, and thus they are universal quantities that can be extrapolated from one flow to another, at least among different flows sharing the same characteristics such as separation. This finding has profound implications to the future development of RANS models, opening up new ...
Mesh Generation and Adaption for High Reynolds Number RANS Computations Project
National Aeronautics and Space Administration — This proposal offers to provide NASA with an automatic mesh generator for the simulation of aerodynamic flows using Reynolds-Averages Navier-Stokes (RANS) models....
2017-10-01
turbine blade with large incidence and Reynolds number variations. AIAA-2014-3933. Proceedings of the 50th AIAA/ ASME /SAE/ASEE Joint Propulsion...pressure field and loss. ASME J Turbomach. 2000;123(2):296–304. Approved for public release; distribution is unlimited. 26 9. Menter FR, Langtry...dimensional Navier- stokes analysis and redesign of an imbedded bellmouth nozzle in a turbine cascade inlet section. ASME Journal of Turbomachinery
Wang, Jian-Xun; Xiao, Heng
2016-01-01
Turbulence modeling is a critical component in numerical simulations of industrial flows based on Reynolds-averaged Navier-Stokes (RANS) equations. However, after decades of efforts in the turbulence modeling community, universally applicable RANS models with predictive capabilities are still lacking. Recently, data-driven methods have been proposed as a promising alternative to the traditional approaches of turbulence model development. In this work we propose a data-driven, physics-informed machine learning approach for predicting discrepancies in RANS modeled Reynolds stresses. The discrepancies are formulated as functions of the mean flow features. By using a modern machine learning technique based on random forests, the discrepancy functions are first trained with benchmark flow data and then used to predict Reynolds stresses discrepancies in new flows. The method is used to predict the Reynolds stresses in the flow over periodic hills by using two training flow scenarios of increasing difficulties: (1) ...
Crivellini, A.; D'Alessandro, V.; Di Benedetto, D.; Montelpare, S.; Ricci, R.
2014-04-01
This work is devoted to the Computational Fluid-Dynamics (CFD) simulation of laminar separation bubble (LSB) on low Reynolds number operating airfoils. This phenomenon is of large interest in several fields, such as wind energy, and it is characterised by slow recirculating flow at an almost constant pressure. Presently Reynolds Averaged Navier-Stokes (RANS) methods, due to their limited computational requests, are the more efficient and feasible CFD simulation tool for complex engineering applications involving LSBs. However adopting RANS methods for LSB prediction is very challenging since widely used models assume a fully turbulent regime. For this reason several transitional models for RANS equations based on further Partial Differential Equations (PDE) have been recently introduced in literature. Nevertheless in some cases they show questionable results. In this work RANS equations and the standard Spalart-Allmaras (SA) turbulence model are used to deal with LSB problems obtaining promising results. This innovative result is related to: (i) a particular behaviour of the SA equation; (ii) a particular implementation of SA equation; (iii) the use of a high-order discontinuous Galerkin (DG) solver. The effectiveness of the proposed approach is tested on different airfoils at several angles of attack and Reynolds numbers. Numerical results were verified with both experimental measurements performed at the open circuit subsonic wind tunnel of Università Politecnica delle Marche (UNIVPM) and literature data.
DEFF Research Database (Denmark)
Yang, Yang; Kær, Søren Knudsen
2012-01-01
The flow structure of one isothermal swirling case in the Sydney swirl flame database was studied using two numerical methods. Results from the Reynolds-averaged Navier-Stokes (RANS) approach and large eddy simulation (LES) were compared with experimental measurements. The simulations were applie...... deducted from the two methods were different. The vorticity field was also studied using a velocity gradient based method. This research gained in-depth understanding of isothermal swirling flow.......The flow structure of one isothermal swirling case in the Sydney swirl flame database was studied using two numerical methods. Results from the Reynolds-averaged Navier-Stokes (RANS) approach and large eddy simulation (LES) were compared with experimental measurements. The simulations were applied...
Directory of Open Access Journals (Sweden)
Niaz Bahadur Khan
Full Text Available This study numerically investigates the vortex-induced vibration (VIV of an elastically mounted rigid cylinder by using Reynolds-averaged Navier-Stokes (RANS equations with computational fluid dynamic (CFD tools. CFD analysis is performed for a fixed-cylinder case with Reynolds number (Re = 104 and for a cylinder that is free to oscillate in the transverse direction and possesses a low mass-damping ratio and Re = 104. Previously, similar studies have been performed with 3-dimensional and comparatively expensive turbulent models. In the current study, the capability and accuracy of the RANS model are validated, and the results of this model are compared with those of detached eddy simulation, direct numerical simulation, and large eddy simulation models. All three response branches and the maximum amplitude are well captured. The 2-dimensional case with the RANS shear-stress transport k-w model, which involves minimal computational cost, is reliable and appropriate for analyzing the characteristics of VIV.
Energy Technology Data Exchange (ETDEWEB)
Benarafa, Y
2005-12-15
The main issue to perform a computational study of high Reynolds numbered turbulent flows consists on predicting their unsteadiness without implying a tremendous computational cost. First, the main drawbacks of large-eddy simulation with standard wall model on a coarse mesh for a plane channel flow are highlighted. To correct these drawbacks two coupling RANS/LES methods have been proposed. The first one relies on a sophisticated wall model (TBLE) which consists on solving Thin Boundary Layer Equations with a RANS type turbulent closure in the near wall region. The second one consists on a RANS/LES methods have been proposed. The second one consists on a RANS/LES coupling method using a forcing term approach. These various approaches have been implemented in the TRIO-U code developed at CEA (French Atomic Center) at Grenoble, France. The studied flow configurations are the fully developed plane channel flow and a flow around a surface-mounted cubical obstacle. Both approaches provide encouraging results and allow a surface-mounted cubical obstacle. Both approaches provide encouraging results and allow unsteady simulations for a low computational cost. (author)
Reynolds-averaged Navier-Stokes and Large-Eddy Simulation Over and Inside Inhomogeneous Forests
DEFF Research Database (Denmark)
Boudreault, Louis-Etienne
the performance of wind models in such environment.A systematic method to acquire gridded input of canopy structure from aircraft based LiDAR scans of heterogeneous forests is defined. An extensive validation against ground-based measurements of the vertically summed frontal area density(or plant area index......) and tree height is performed. The method is optimized both in terms of plant area index magnitude and spatial variability. A forest grid is generated from the LiDAR method using airplane scans of a 5×5 km2 forested site in Sweden. The grid serves as the basis for Reynolds-averaged Navier-Stokes (RANS......) simulations. Wind observations from an instrumented mast are used for validation where a good correlation is found for the mean wind speed of two contrasting wind directions with different influences from the upstream forest. The effects of successive simplifications of the forest representation show...
Hybrid RANS/LES method for high Reynolds numbers, applied to atmospheric flow over complex terrain
DEFF Research Database (Denmark)
Bechmann, Andreas; Sørensen, Niels N.; Johansen, Jeppe
2007-01-01
The use of Large-Eddy Simulation (LES) to predict wall-bounded flows has presently been limited to low Reynolds number flows. Since the number of computational grid points required to resolve the near-wall turbulent structures increase rapidly with Reynolds number, LES has been unattainable for...
Reynolds-Averaged Navier-Stokes Simulation of a 2D Circulation Control Wind Tunnel Experiment
Allan, Brian G.; Jones, Greg; Lin, John C.
2011-01-01
Numerical simulations are performed using a Reynolds-averaged Navier-Stokes (RANS) flow solver for a circulation control airfoil. 2D and 3D simulation results are compared to a circulation control wind tunnel test conducted at the NASA Langley Basic Aerodynamics Research Tunnel (BART). The RANS simulations are compared to a low blowing case with a jet momentum coefficient, C(sub u), of 0:047 and a higher blowing case of 0.115. Three dimensional simulations of the model and tunnel walls show wall effects on the lift and airfoil surface pressures. These wall effects include a 4% decrease of the midspan sectional lift for the C(sub u) 0.115 blowing condition. Simulations comparing the performance of the Spalart Allmaras (SA) and Shear Stress Transport (SST) turbulence models are also made, showing the SST model compares best to the experimental data. A Rotational/Curvature Correction (RCC) to the turbulence model is also evaluated demonstrating an improvement in the CFD predictions.
Gorlé, C.; Iaccarino, G.
2013-05-01
Reynolds-averaged Navier-Stokes (RANS) simulations are a practical approach for solving complex multi-physics turbulent flows, but the underlying assumptions of the turbulence models introduce errors and uncertainties in the simulation outcome. The flow in scramjet combustors is an example of such a complex flow and the accurate characterization of safety and operability limits of these engines using RANS simulations requires an assessment of the model uncertainty. The objective of this paper is to present a framework for the epistemic uncertainty quantification of turbulence and mixing models in RANS simulations. The capabilities of the methodology will be demonstrated by performing simulations of the mixing of an underexpanded jet in a supersonic cross flow, which involves many flow features observed in scramjet engines. The fundamental sources of uncertainty in the RANS simulations are the models used for the Reynolds stresses in the momentum equations and the turbulent scalar fluxes in the scalar transport equations. The methodology consists in directly perturbing the modeled quantities in the equations, thereby establishing a method that is completely independent of the initial model form to overcome the limitations of traditional sensitivity studies. The perturbations are defined in terms of the decomposed Reynolds stress tensor, i.e., the tensor magnitude and the eigenvalues and eigenvectors of the normalized anisotropy tensor. The turbulent scalar fluxes are perturbed by using the perturbed Reynolds stresses in a generalized gradient diffusion model formulation and by changing the model constant. The perturbations were parameterized based on a comparison between the Reynolds stresses obtained from a baseline RANS simulation and those obtained from a large-eddy simulation database. Subsequently an optimization problem was solved, varying the parameters in the perturbation functions to maximize a quantity of interest that quantifies the downstream mixing. The
Cappelli, Daniele; Mansour, Nagi N.
2012-01-01
Separation can be seen in most aerodynamic flows, but accurate prediction of separated flows is still a challenging problem for computational fluid dynamics (CFD) tools. The behavior of several Reynolds Averaged Navier-Stokes (RANS) models in predicting the separated ow over a wall-mounted hump is studied. The strengths and weaknesses of the most popular RANS models (Spalart-Allmaras, k-epsilon, k-omega, k-omega-SST) are evaluated using the open source software OpenFOAM. The hump ow modeled in this work has been documented in the 2004 CFD Validation Workshop on Synthetic Jets and Turbulent Separation Control. Only the baseline case is treated; the slot flow control cases are not considered in this paper. Particular attention is given to predicting the size of the recirculation bubble, the position of the reattachment point, and the velocity profiles downstream of the hump.
Uddin, M. Maruf; Fuad, Muzaddid-E.-Zaman; Rahaman, Md. Mashiur; Islam, M. Rabiul
2017-12-01
With the rapid decrease in the cost of computational infrastructure with more efficient algorithm for solving non-linear problems, Reynold's averaged Navier-Stokes (RaNS) based Computational Fluid Dynamics (CFD) has been used widely now-a-days. As a preliminary evaluation tool, CFD is used to calculate the hydrodynamic loads on offshore installations, ships, and other structures in the ocean at initial design stages. Traditionally, wedges have been studied more than circular cylinders because cylinder section has zero deadrise angle at the instant of water impact, which increases with increase of submergence. In Present study, RaNS based commercial code ANSYS Fluent is used to simulate the water entry of a circular section at constant velocity. It is seen that present computational results were compared with experiment and other numerical method.
Xiao, H; Wang, J -X; Sun, R; Roy, C J
2015-01-01
Despite their well-known limitations, Reynolds-Averaged Navier-Stokes (RANS) models are still the workhorse tools for turbulent flow simulations in today's engineering applications. For many practical flows, the turbulence models are by far the most important source of uncertainty. In this work we develop an open-box, physics-informed Bayesian framework for quantifying model-form uncertainties in RANS simulations. Uncertainties are introduced directly to the Reynolds stresses and are represented with compact parameterization accounting for empirical prior knowledge and physical constraints (e.g., realizability, smoothness, and symmetry). An iterative ensemble Kalman method is used to assimilate the prior knowledge and observation data in a Bayesian framework, and to propagate them to posterior distributions of velocities and other Quantities of Interest (QoIs). We use two representative cases, the flow over periodic hills and the flow in a square duct, to evaluate the performance of the proposed framework. Si...
Xiao, H.; Wu, J.-L.; Wang, J.-X.; Sun, R.; Roy, C. J.
2016-11-01
Despite their well-known limitations, Reynolds-Averaged Navier-Stokes (RANS) models are still the workhorse tools for turbulent flow simulations in today's engineering analysis, design and optimization. While the predictive capability of RANS models depends on many factors, for many practical flows the turbulence models are by far the largest source of uncertainty. As RANS models are used in the design and safety evaluation of many mission-critical systems such as airplanes and nuclear power plants, quantifying their model-form uncertainties has significant implications in enabling risk-informed decision-making. In this work we develop a data-driven, physics-informed Bayesian framework for quantifying model-form uncertainties in RANS simulations. Uncertainties are introduced directly to the Reynolds stresses and are represented with compact parameterization accounting for empirical prior knowledge and physical constraints (e.g., realizability, smoothness, and symmetry). An iterative ensemble Kalman method is used to assimilate the prior knowledge and observation data in a Bayesian framework, and to propagate them to posterior distributions of velocities and other Quantities of Interest (QoIs). We use two representative cases, the flow over periodic hills and the flow in a square duct, to evaluate the performance of the proposed framework. Both cases are challenging for standard RANS turbulence models. Simulation results suggest that, even with very sparse observations, the obtained posterior mean velocities and other QoIs have significantly better agreement with the benchmark data compared to the baseline results. At most locations the posterior distribution adequately captures the true model error within the developed model form uncertainty bounds. The framework is a major improvement over existing black-box, physics-neutral methods for model-form uncertainty quantification, where prior knowledge and details of the models are not exploited. This approach has
Reynolds-averaged Navier-Stokes based ice accretion for aircraft wings
Lashkajani, Kazem Hasanzadeh
This thesis addresses one of the current issues in flight safety towards increasing icing simulation capabilities for prediction of complex 2D and 3D glaze ice shapes over aircraft surfaces. During the 1980's and 1990's, the field of aero-icing was established to support design and certification of aircraft flying in icing conditions. The multidisciplinary technologies used in such codes were: aerodynamics (panel method), droplet trajectory calculations (Lagrangian framework), thermodynamic module (Messinger model) and geometry module (ice accretion). These are embedded in a quasi-steady module to simulate the time-dependent ice accretion process (multi-step procedure). The objectives of the present research are to upgrade the aerodynamic module from Laplace to Reynolds-Average Navier-Stokes equations solver. The advantages are many. First, the physical model allows accounting for viscous effects in the aerodynamic module. Second, the solution of the aero-icing module directly provides the means for characterizing the aerodynamic effects of icing, such as loss of lift and increased drag. Third, the use of a finite volume approach to solving the Partial Differential Equations allows rigorous mesh and time convergence analysis. Finally, the approaches developed in 2D can be easily transposed to 3D problems. The research was performed in three major steps, each providing insights into the overall numerical approaches. The most important realization comes from the need to develop specific mesh generation algorithms to ensure feasible solutions in very complex multi-step aero-icing calculations. The contributions are presented in chronological order of their realization. First, a new framework for RANS based two-dimensional ice accretion code, CANICE2D-NS, is developed. A multi-block RANS code from U. of Liverpool (named PMB) is providing the aerodynamic field using the Spalart-Allmaras turbulence model. The ICEM-CFD commercial tool is used for the iced airfoil
Energy Technology Data Exchange (ETDEWEB)
Xiao, H., E-mail: hengxiao@vt.edu; Wu, J.-L.; Wang, J.-X.; Sun, R.; Roy, C.J.
2016-11-01
Despite their well-known limitations, Reynolds-Averaged Navier–Stokes (RANS) models are still the workhorse tools for turbulent flow simulations in today's engineering analysis, design and optimization. While the predictive capability of RANS models depends on many factors, for many practical flows the turbulence models are by far the largest source of uncertainty. As RANS models are used in the design and safety evaluation of many mission-critical systems such as airplanes and nuclear power plants, quantifying their model-form uncertainties has significant implications in enabling risk-informed decision-making. In this work we develop a data-driven, physics-informed Bayesian framework for quantifying model-form uncertainties in RANS simulations. Uncertainties are introduced directly to the Reynolds stresses and are represented with compact parameterization accounting for empirical prior knowledge and physical constraints (e.g., realizability, smoothness, and symmetry). An iterative ensemble Kalman method is used to assimilate the prior knowledge and observation data in a Bayesian framework, and to propagate them to posterior distributions of velocities and other Quantities of Interest (QoIs). We use two representative cases, the flow over periodic hills and the flow in a square duct, to evaluate the performance of the proposed framework. Both cases are challenging for standard RANS turbulence models. Simulation results suggest that, even with very sparse observations, the obtained posterior mean velocities and other QoIs have significantly better agreement with the benchmark data compared to the baseline results. At most locations the posterior distribution adequately captures the true model error within the developed model form uncertainty bounds. The framework is a major improvement over existing black-box, physics-neutral methods for model-form uncertainty quantification, where prior knowledge and details of the models are not exploited. This approach
Jones, Sam; Jemcov, Aleksandar; Corke, Thomas
2016-11-01
An Embedded Large Eddy Simulation (ELES) approach is used to simulate the flow path through a high pressure turbine stage that includes the entry duct, stationary inlet and exit guide vanes, and a rotor. The flowfield around the rotor is simulated using LES. A Reynolds Averaged Simulation (RAS) is used for the rest of the flow domain. The interface between RAS and LES domains uses the RAS turbulence quantities as a means of obtaining length scales that are used in computing the vorticity required to trigger a proper energy cascade within the LES part of the flow field. The objective is to resolve the unsteady vortical motions that eminate from the gap between the rotor tip and duct walls that are presumably under-resolved in a RAS approach. A comparative analysis between RAS and ELES approaches for this turbomachinery problem is then presented. APS Fellow.
Reynolds-Averaged Turbulence Model Assessment for a Highly Back-Pressured Isolator Flowfield
Baurle, Robert A.; Middleton, Troy F.; Wilson, L. G.
2012-01-01
The use of computational fluid dynamics in scramjet engine component development is widespread in the existing literature. Unfortunately, the quantification of model-form uncertainties is rarely addressed with anything other than sensitivity studies, requiring that the computational results be intimately tied to and calibrated against existing test data. This practice must be replaced with a formal uncertainty quantification process for computational fluid dynamics to play an expanded role in the system design, development, and flight certification process. Due to ground test facility limitations, this expanded role is believed to be a requirement by some in the test and evaluation community if scramjet engines are to be given serious consideration as a viable propulsion device. An effort has been initiated at the NASA Langley Research Center to validate several turbulence closure models used for Reynolds-averaged simulations of scramjet isolator flows. The turbulence models considered were the Menter BSL, Menter SST, Wilcox 1998, Wilcox 2006, and the Gatski-Speziale explicit algebraic Reynolds stress models. The simulations were carried out using the VULCAN computational fluid dynamics package developed at the NASA Langley Research Center. A procedure to quantify the numerical errors was developed to account for discretization errors in the validation process. This procedure utilized the grid convergence index defined by Roache as a bounding estimate for the numerical error. The validation data was collected from a mechanically back-pressured constant area (1 2 inch) isolator model with an isolator entrance Mach number of 2.5. As expected, the model-form uncertainty was substantial for the shock-dominated, massively separated flowfield within the isolator as evidenced by a 6 duct height variation in shock train length depending on the turbulence model employed. Generally speaking, the turbulence models that did not include an explicit stress limiter more closely
Dejoan, A.; Santiago, J. L.; Martilli, A.; Martin, F.; Pinelli, A.
2010-04-01
Large-eddy simulations (LES) and Reynolds-averaged Navier-Stokes (RANS) computations of pollutant dispersion are reported for the Mock Urban Setting Test (MUST) field experiment flow. In particular we address the effects of incident wind angle deviation on the mean velocity and on the mean concentration fields. Both computational fluid dynamical methods are assessed by comparing the simulation results with experimental field data. The comparative analysis proposes to relate the plume deflection with the flow channelling effects. The results show that the plume deflection angle varies with the altitude. As the ground is approached the plume is shown to be almost aligned with the street canyon direction and independent of the incident wind directions considered. At higher altitudes well above the obstacles, the plume direction is aligned with the mean wind direction as in dispersion over flat terrain. The near-ground plume deflection is the consequence of a strong channelling effect in the region near the ground. The mean concentration profiles predicted by LES and RANS are both in good qualitative agreement with experimental data but exhibit discrepancies that can be partly explained by the influence of small incident wind angle deviation effects. Compared to RANS, LES predicts a higher channelling and thus a higher deflection of the plume. Results on the fluctuating intensity of the concentration obtained from LES show a satisfactory agreement with experiments. This information is not available from RANS for which only the mean concentration modelling is considered.
Spotts, Nathan
As modern trends in commercial aircraft design move toward high-bypass-ratio fan systems of increasing diameter with shorter, nonaxisymmetric nacelle geometries, inlet distortion is becoming common in all operating regimes. The distortion may induce aerodynamic instabilities within the fan system, leading to catastrophic damage to fan blades, should the surge margin be exceeded. Even in the absence of system instability, the heterogeneity of the flow affects aerodynamic performance significantly. Therefore, an understanding of fan-distortion interaction is critical to aircraft engine system design. This thesis research elucidates the complex fluid dynamics and fan-distortion interaction by means of computational fluid dynamics (CFD) modeling of a complete engine fan system; including rotor, stator, spinner, nacelle and nozzle; under conditions typical of those encountered by commercial aircraft. The CFD simulations, based on a Reynolds-averaged Navier-Stokes (RANS) approach, were unsteady, three-dimensional, and of a full-annulus geometry. A thorough, systematic validation has been performed for configurations from a single passage of a rotor to a full-annulus system by comparing the predicted flow characteristics and aerodynamic performance to those found in literature. The original contributions of this research include the integration of a complete engine fan system, based on the NASA rotor 67 transonic stage and representative of the propulsion systems in commercial aircraft, and a benchmark case for unsteady RANS simulations of distorted flow in such a geometry under realistic operating conditions. This study is unique in that the complex flow dynamics, resulting from fan-distortion interaction, were illustrated in a practical geometry under realistic operating conditions. For example, the compressive stage is shown to influence upstream static pressure distributions and thus suppress separation of flow on the nacelle. Knowledge of such flow physics is
Assessment of an Explicit Algebraic Reynolds Stress Model
Carlson, Jan-Renee
2005-01-01
This study assesses an explicit algebraic Reynolds stress turbulence model in the in the three-dimensional Reynolds averaged Navier-Stokes (RANS) solver, ISAAC (Integrated Solution Algorithm for Arbitrary Con gurations). Additionally, it compares solutions for two select configurations between ISAAC and the RANS solver PAB3D. This study compares with either direct numerical simulation data, experimental data, or empirical models for several different geometries with compressible, separated, and high Reynolds number flows. In general, the turbulence model matched data or followed experimental trends well, and for the selected configurations, the computational results of ISAAC closely matched those of PAB3D using the same turbulence model.
Brown, James L.
2014-01-01
Examined is sensitivity of separation extent, wall pressure and heating to variation of primary input flow parameters, such as Mach and Reynolds numbers and shock strength, for 2D and Axisymmetric Hypersonic Shock Wave Turbulent Boundary Layer interactions obtained by Navier-Stokes methods using the SST turbulence model. Baseline parametric sensitivity response is provided in part by comparison with vetted experiments, and in part through updated correlations based on free interaction theory concepts. A recent database compilation of hypersonic 2D shock-wave/turbulent boundary layer experiments extensively used in a prior related uncertainty analysis provides the foundation for this updated correlation approach, as well as for more conventional validation. The primary CFD method for this work is DPLR, one of NASA's real-gas aerothermodynamic production RANS codes. Comparisons are also made with CFL3D, one of NASA's mature perfect-gas RANS codes. Deficiencies in predicted separation response of RANS/SST solutions to parametric variations of test conditions are summarized, along with recommendations as to future turbulence approach.
Wang, Jian-Xun; Wu, Jin-Long; Xiao, Heng
2017-03-01
Turbulence modeling is a critical component in numerical simulations of industrial flows based on Reynolds-averaged Navier-Stokes (RANS) equations. However, after decades of efforts in the turbulence modeling community, universally applicable RANS models with predictive capabilities are still lacking. Large discrepancies in the RANS-modeled Reynolds stresses are the main source that limits the predictive accuracy of RANS models. Identifying these discrepancies is of significance to possibly improve the RANS modeling. In this work, we propose a data-driven, physics-informed machine learning approach for reconstructing discrepancies in RANS modeled Reynolds stresses. The discrepancies are formulated as functions of the mean flow features. By using a modern machine learning technique based on random forests, the discrepancy functions are trained by existing direct numerical simulation (DNS) databases and then used to predict Reynolds stress discrepancies in different flows where data are not available. The proposed method is evaluated by two classes of flows: (1) fully developed turbulent flows in a square duct at various Reynolds numbers and (2) flows with massive separations. In separated flows, two training flow scenarios of increasing difficulties are considered: (1) the flow in the same periodic hills geometry yet at a lower Reynolds number and (2) the flow in a different hill geometry with a similar recirculation zone. Excellent predictive performances were observed in both scenarios, demonstrating the merits of the proposed method.
DEFF Research Database (Denmark)
Sørensen, Niels N.; Bechmann, Andreas; Réthoré, Pierre-Elouan
2014-01-01
In the present paper, Reynolds-averaged Navier–Stokes predictions of the flow field around the MEXICO rotor in yawed conditions are compared with measurements. The paper illustrates the high degree of qualitative and quantitative agreement that can be obtained for this highly unsteady flow...
Computing the flow past Vortex Generators : Comparison between RANS Simulations and Experiments
Manolesos, M.; Sorensen, NN; Troldborg, N.; Florentie, L.; Papadakis, G; Voutsinas, S.
2016-01-01
The flow around a wind turbine airfoil equipped with Vortex Generators (VGs) is examined. Predictions from three different Reynolds Averaged Navier Stokes (RANS) solvers with two different turbulence models and two different VG modelling approaches are compared between them and with experimental
Computing the flow past Vortex Generators: Comparison between RANS Simulations and Experiments
DEFF Research Database (Denmark)
Manolesos, M.; Sørensen, Niels N.; Troldborg, Niels
2016-01-01
The flow around a wind turbine airfoil equipped with Vortex Generators (VGs) is examined. Predictions from three different Reynolds Averaged Navier Stokes (RANS) solvers with two different turbulence models and two different VG modelling approaches are compared between them and with experimental ...
Analysis of vegetation effect on waves using a vertical 2-D RANS model
A vertical two-dimensional (2-D) model has been applied in the simulation of wave propagation through vegetated water bodies. The model is based on an existing model SOLA-VOF which solves the Reynolds-Averaged Navier-Stokes (RANS) equations with the finite difference method on a staggered rectangula...
Directory of Open Access Journals (Sweden)
De-You Li
2016-06-01
Full Text Available For pump–turbines, most of the instabilities couple with high-level pressure fluctuations, which are harmful to pump–turbines, even the whole units. In order to understand the causes of pressure fluctuations and reduce their amplitudes, proper numerical methods should be chosen to obtain the accurate results. The method of large eddy simulation with wall-adapting local eddy-viscosity model was chosen to predict the pressure fluctuations in pump mode of a pump–turbine compared with the method of unsteady Reynolds-averaged Navier–Stokes with two-equation turbulence model shear stress transport k–ω. Partial load operating point (0.91QBEP under 15-mm guide vane opening was selected to make a comparison of performance and frequency characteristics between large eddy simulation and unsteady Reynolds-averaged Navier–Stokes based on the experimental validation. Good agreement indicates that the method of large eddy simulation could be applied in the simulation of pump–turbines. Then, a detailed comparison of variation for peak-to-peak value in the whole passage was presented. Both the methods show that the highest level pressure fluctuations occur in the vaneless space. In addition, the propagation of amplitudes of blade pass frequency, 2 times of blade pass frequency, and 3 times of blade pass frequency in the circumferential and flow directions was investigated. Although the difference exists between large eddy simulation and unsteady Reynolds-averaged Navier–Stokes, the trend of variation in different parts is almost the same. Based on the analysis, using the same mesh (8 million, large eddy simulation underestimates pressure characteristics and shows a better result compared with the experiments, while unsteady Reynolds-averaged Navier–Stokes overestimates them.
Quantifying Model Form Uncertainty in RANS Simulation of Wing-Body Junction Flow
Wu, Jin-Long; Xiao, Heng
2016-01-01
Wing-body junction flows occur when a boundary layer encounters an airfoil mounted on the surface. The corner flow near the trailing edge is challenging for the linear eddy viscosity Reynolds Averaged Navier-Stokes (RANS) models, due to the interaction of two perpendicular boundary layers which leads to highly anisotropic Reynolds stress at the near wall region. Recently, Xiao et al. proposed a physics-informed Bayesian framework to quantify and reduce the model-form uncertainties in RANS simulations by utilizing sparse observation data. In this work, we extend this framework to incorporate the use of wall function in RANS simulations, and apply the extended framework to the RANS simulation of wing-body junction flow. Standard RANS simulations are performed on a 3:2 elliptic nose and NACA0020 tail cylinder joined at their maximum thickness location. Current results show that both the posterior mean velocity and the Reynolds stress anisotropy show better agreement with the experimental data at the corner regio...
A Discussion of Low Reynolds Number Flow for the Two-Dimensional Benchmark Test Case
DEFF Research Database (Denmark)
Weng, Miaocheng; Nielsen, Peter V.; Liu, Li
The use of CFD in ventilation research has arrived to a high level, but there are some conditions in the general CFD procedure which do not apply to all situations in the ventilation research. An example of this isthe turbulence models in Reynolds-averaged Navier-Stokes equations, i.e. (RANS) equ...
Lopez Varilla, Maurin Alberto
One of the biggest unsolved problems of modern physics is the turbulence phenomena in fluid flow. The appearance of turbulence in a flow system is regularly determined by velocity and length scales of the system. If those scales are small the motion of the fluid is laminar, but at larger scales, disturbances appear and grow, leading the flow field to transition to a fully turbulent state. The prediction of transitional flow is critical for many complex fluid flow applications, such as aeronautical, aerospace, biomedical, automotive, chemical processing, heating and cooling systems, and meteorology. For example, in some cases the flow may remain laminar throughout a significant portion of a given domain, and fully turbulent simulations may produce results that can lead to inaccurate conclusions or inefficient design, due to an inability to resolve the details of the transition process. This work aims to develop, implement, and test a new model concept for the prediction of transitional flows using a linear eddy-viscosity RANS approach. The effects of transition are included through one additional transport equation for upsilon 2 as an alternative to the Laminar Kinetic Energy (LKE) framework. Here upsilon2 is interpreted as the energy of fully turbulent, three-dimensional velocity fluctuations. The concept is based on a description of the transition process previously discussed by Walters. This dissertation presents two new single-point, physics-based turbulence models based on the transitional methodology mentioned above. The first one uses an existing transitional model as a baseline which is modified to accurately capture the physics of fully turbulent free shear flows. The model formulation was tested over several boundary layer and free shear flow test cases. The simulations show accurate results, qualitatively equal to the baseline model on transitional boundary layer test cases, and substantially improved over the baseline model for free shear flows. The
Computing the flow past Vortex Generators: Comparison between RANS Simulations and Experiments
Manolesos, M.; Sørensen, N. N.; Troldborg, N.; Florentie, L.; Papadakis, G.; Voutsinas, S.
2016-09-01
The flow around a wind turbine airfoil equipped with Vortex Generators (VGs) is examined. Predictions from three different Reynolds Averaged Navier Stokes (RANS) solvers with two different turbulence models and two different VG modelling approaches are compared between them and with experimental data. The best results are obtained with the more expensive fully resolved VG approach. The cost efficient BAY model can also provide acceptable results, if grid related numerical diffusion is minimized and only force coefficient polars are considered.
Propeller Analysis Using RANS/BEM Coupling Accounting for Blade Blockage
2015-07-04
2000 and 2010 Gothenburg and 2005 Tokyo workshops on numerical ship hydrodynamics (Larrson et al., 2002, Larsson et al. 2013, Hino 2005). The KCS is...Workshop on Numerical Ship Hydrodynamics, Chalmers University of Technology. Larsson , L., Stern, F. and Visonneau, M. (eds.), (2013). Numerical ...B2Y 3Z7 ABSTRACT A popular method for analyzing a propeller operating behind a ship is to couple a Reynolds-averaged Navier- Stokes (RANS) solution
RANS/CAA based Prediction of Jet Mixing Noise in Cruise Flight
Appel, Christina; Rossignol, Karl-Stéphane; Klabes, Alexander; Neifeld, Andrej; Herr, Michaela; Ewert, Roland
2014-01-01
Besides turbulent boundary layer induced excitation noise, jet noise is the second most important aeroacoustic source for aircraft cabin noise. A goal within the DLR project ECCO (Enhanced Cabin Comfort Computations) was to improve current cabin noise pre- diction approaches. Within the framework of the project ECCO RANS (Reynolds Averaged Navier Stokes) and CAA (Computational Aero Acoustics) computations for jet noise at cruise conditions have been carried out. Especially at h...
Assessment of 3D-RANS models for the simulation of topographically forced shallow flows
Directory of Open Access Journals (Sweden)
Safarzadeh Akbar
2016-03-01
Full Text Available In this work the performance of Reynolds Averaged Navier-Stokes (RANS simulations to predict the flow structure developed by the presence of a sidewall obstacle in a uniform open-channel shallow flow is discussed. The tested geometry was selected due to its important role in several fluvial applications, such as the control of riverbank erosion and the creation of improved ecological conditions in river restoration applications. The results are compared against experimental laboratory velocity fields obtained after Large Scale Particle Image Velocimetry (LSPIV measurements. It is shown that the length of reattachment of the separated shear layer generated by the obstacle is well predicted by a Reynolds Stress Model, while classical two-equation models show important limitations. All the performed RANS simulations are unable to properly predict the formation of a secondary gyre region, which develops immediately downstream the obstacle.
A Study of Low-Reynolds Number Effects in Backward-Facing Step Flow Using Large Eddy Simulations
DEFF Research Database (Denmark)
Davidson, Lars; Nielsen, Peter V.
The flow in ventilated rooms is often not fully turbulent, but in some regions the flow can be laminar. Problems have been encountered when simulating this type of flow using RANS (Reynolds Averaged Navier-Stokes) methods. Restivo carried out experiment on the flow after a backward-facing step......, with a large step....
Development of a Hybrid RANS/LES Method for Compressible Mixing Layer Simulations
Georgiadis, Nicholas J.; Alexander, J. Iwan D.; Reshotko, Eli
2001-01-01
A hybrid method has been developed for simulations of compressible turbulent mixing layers. Such mixing layers dominate the flows in exhaust systems of modem day aircraft and also those of hypersonic vehicles currently under development. The hybrid method uses a Reynolds-averaged Navier-Stokes (RANS) procedure to calculate wall bounded regions entering a mixing section, and a Large Eddy Simulation (LES) procedure to calculate the mixing dominated regions. A numerical technique was developed to enable the use of the hybrid RANS/LES method on stretched, non-Cartesian grids. The hybrid RANS/LES method is applied to a benchmark compressible mixing layer experiment. Preliminary two-dimensional calculations are used to investigate the effects of axial grid density and boundary conditions. Actual LES calculations, performed in three spatial directions, indicated an initial vortex shedding followed by rapid transition to turbulence, which is in agreement with experimental observations.
Moran-Lopez, Tiberius; Schilling, Oleg
2013-11-01
Reshocked Richtmyer-Meshkov turbulent mixing of gases with various Atwood numbers and shock Mach numbers is simulated using a third-order weighted essentially nonoscillatory implementation of a K- ɛ multicomponent Reynolds-averaged Navier-Stokes model. First, mixing layer widths from simulations with Mach number Ma = 1 . 20 , Atwood number At = 0 . 67 (air/SF6), and different times of reshock are shown to be in very good agreement with the experimental data of Leinov et al. [J. Fluid Mech. 626, 449 (2009)]. Second, widths from simulations with Ma = 1 . 50 and At = +/- 0 . 21 , +/- 0 . 67 and +/- 0 . 87 (corresponding to air/CO2, air/SF6 and H2/air) are compared to the large-eddy simulation data of Lombardini et al. [J. Fluid Mech. 670, 439 (2011)] and discussed. Budgets of the turbulent transport equations are considered to elucidate the mechanisms contributing to turbulent mixing in reshocked Richtmyer-Meshkov instability. Convergence of the mixing layer widths, mean fields, and turbulent fields under grid refinement is also assessed. This work was funded by the U. S. Department of Energy NNSA under the Predictive Science Academic Alliances Program by grant DE-FC52-08NA28616 and performed under the auspices of the DOE by LLNL under Contract DE-AC52-s07NA27344.
A dynamic hybrid RANS/LES modeling methodology for turbulent/transitional flow field prediction
Alam, Mohammad Faridul
A dynamic hybrid Reynolds-averaged Navier-Stokes (RANS)-Large Eddy Simulation (LES) modeling framework has been investigated and further developed to improve the Computational Fluid Dynamics (CFD) prediction of turbulent flow features along with laminar-to-turbulent transitional phenomena. In recent years, the use of hybrid RANS/LES (HRL) models has become more common in CFD simulations, since HRL models offer more accuracy than RANS in regions of flow separation at a reduced cost relative to LES in attached boundary layers. The first part of this research includes evaluation and validation of a dynamic HRL (DHRL) model that aims to address issues regarding the RANS-to-LES zonal transition and explicit grid dependence, both of which are inherent to most current HRL models. Simulations of two test cases---flow over a backward facing step and flow over a wing with leading-edge ice accretion---were performed to assess the potential of the DHRL model for predicting turbulent features involved in mainly unsteady separated flow. The DHRL simulation results are compared with experimental data, along with the computational results for other HRL and RANS models. In summary, these comparisons demonstrate that the DHRL framework does address many of the weaknesses inherent in most current HRL models. Although HRL models are widely used in turbulent flow simulations, they have limitations for transitional flow predictions. Most HRL models include a fully turbulent RANS component for attached boundary layer regions. The small number of HRL models that do include transition-sensitive RANS models have issues related to the RANS model itself and to the zonal transition between RANS and LES. In order to address those issues, a new transition-sensitive HRL modeling methodology has been developed that includes the DHRL methodology and a physics-based transition-sensitive RANS model. The feasibility of the transition-sensitive dynamic HRL (TDHRL) model has been investigated by
Chitta, Varun
Lifting surfaces of unmanned aerial vehicles (UAV) are often operated in low Reynolds number (Re) ranges, wherein the transition of boundary layer from laminar-to-turbulent plays a more significant role than in high-Re aerodynamics applications. This poses a challenge for traditional computational fluid dynamics (CFD) simulations, since typical modeling approaches assume either fully laminar or fully turbulent flow. In particular, the boundary layer state must be accurately predicted to successfully determine the separation behavior which significantly influences the aerodynamic characteristics of the airfoil. Reynolds-averaged Navier-Stokes (RANS) based CFD simulations of an elliptic airfoil are performed for time-varying angles of attack, and results are used to elucidate relevant flow physics and aerodynamic data for an elliptic airfoil under realistic operating conditions. Results are also used to evaluate the performance of several different RANS-based turbulence modeling approaches for this class of flowfield.
Quinlan, Jesse R.; Drozda, Tomasz G.; McDaniel, James C.; Lacaze, Guilhem; Oefelein, Joseph
2015-01-01
In an effort to make large eddy simulation of hydrocarbon-fueled scramjet combustors more computationally accessible using realistic chemical reaction mechanisms, a compressible flamelet/progress variable (FPV) model was proposed that extends current FPV model formulations to high-speed, compressible flows. Development of this model relied on observations garnered from an a priori analysis of the Reynolds-Averaged Navier-Stokes (RANS) data obtained for the Hypersonic International Flight Research and Experimentation (HI-FiRE) dual-mode scramjet combustor. The RANS data were obtained using a reduced chemical mechanism for the combustion of a JP-7 surrogate and were validated using avail- able experimental data. These RANS data were then post-processed to obtain, in an a priori fashion, the scalar fields corresponding to an FPV-based modeling approach. In the current work, in addition to the proposed compressible flamelet model, a standard incompressible FPV model was also considered. Several candidate progress variables were investigated for their ability to recover static temperature and major and minor product species. The effects of pressure and temperature on the tabulated progress variable source term were characterized, and model coupling terms embedded in the Reynolds- averaged Navier-Stokes equations were studied. Finally, results for the novel compressible flamelet/progress variable model were presented to demonstrate the improvement attained by modeling the effects of pressure and flamelet boundary conditions on the combustion.
Comparisons of LES and RANS Computations with PIV Experiments on a Cylindrical Cavity Flow
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Wen-Tao Su
2013-01-01
Full Text Available A comparison study on the numerical computations by large eddy simulation (LES and Reynolds-averaged Navier-Stokes (RANS methods with experiment on a cylindrical cavity flow was conducted in this paper. Numerical simulations and particle image velocimetry (PIV measurement were performed for two Reynolds numbers of the flow at a constant aspect ratio of H/R = 2.4 (R is the radius of the cylindrical cavity, and H is liquid level. The three components of velocity were extracted from 100 sequential PIV measured velocity frames with averaging, in order to illustrate the axial jet flow evolution and circulation distribution in the radial direction. The results show that LES can reproduce well the fine structure inside the swirling motions in both the meridional and the horizontal planes, as well as the distributions of velocity components and the circulation, in good agreement with experimental results, while the RANS method only provided a rough trend of inside vortex structure. Based on the analysis of velocity profiles at various locations, it indicates that LES is more suitable for predicting the complex flow characteristics inside complicated three-dimensional geometries.
Reynolds number effects on the performance and near-wake of a cross-flow turbine
Bachant, Peter; Wosnik, Martin
2013-11-01
To design wind or marine hydrokinetic (MHK) turbine farms with high efficiency, interactions between turbine wakes must be accurately predicted. However, to date numerical models predicting detailed wake properties of cross-flow (or vertical-axis) turbines have been validated with experimental data taken at Reynolds numbers significantly lower than those of full scale devices, casting doubt on the models' accuracy. To address this uncertainty, we investigated the effects of Reynolds number on the performance and near-wake characteristics of a 3-bladed cross-flow turbine, both experimentally and numerically. Mechanical power output and overall streamwise drag were measured in a towing tank at turbine diameter Reynolds numbers ReD = 0 . 5 ×105 - 2 . 0 ×106 . A detailed map of the near-wake one turbine diameter downstream was acquired via acoustic Doppler velocimetry for each Reynolds number case, from which differences in the mean velocity, turbulence intensity, and Reynolds stresses are highlighted. Finally, Reynolds-averaged Navier-Stokes (RANS) numerical simulations were performed, the results from which are compared with the experimental data. Work supported by NSF-CBET grant 1150797.
Evaluation of energy and cost savings in mobile Cloud RAN
DEFF Research Database (Denmark)
Checko, Aleksandra; Christiansen, Henrik Lehrmann; Berger, Michael Stübert
2013-01-01
The load in mobile networks is subject to variations during the day, due to user mobility and varying network average usage. Therefore, the traditional or Distributed Radio Access Network (D-RAN) architecture, where the BaseBand processing Units (BBUs) are assigned statically to a number of cells...... using OPNET Modeler. A real case scenario is built upon the mobile traffic forecast for year 2017, a number of recommendations on traffic models and a proposed C-RAN implementation. The results achieved show that the maximum statistical multiplexing gain for user plane traffic in C-RAN architecture is 4......, is sub optimal, comparing to a novel, cloud based architecture called Cloud Radio Access Network (C-RAN). In C-RAN a group of cells shares processing resources, and hence benefit from statistical multiplexing gain is expected. In this paper, the energy and cost savings in C-RAN are evaluated numerically...
Directory of Open Access Journals (Sweden)
Marcus Sasson
2016-04-01
Full Text Available The oil and gas industry requires complex subsea infrastructure in order to develop offshore oil and gas fields. Upon installation, these components may encounter high slamming loads, stemming from impact with the water surface. This paper utilises two different numerical methods, the mesh-free Smoothed Particle Hydrodynamics (SPH approach and Reynolds Averaged Navier–Stokes (RANS Volume of Fluid (VOF method to quantify these loads on a free-falling object. The investigation is also interested in conducting a parameter study and determining the effect of varying simulation parameters on the prediction of slamming event kinematics and forces. The surface impact of a freefalling wedge was introduced as a case study and has been simulated using SPH and RANS, with the results being compared to an experimental investigation. It was found from the SPH simulations that particle resolution and the size of the SPH particle kernel are very important, whilst the diffusion term does not play an important role. The latter is due to the very transient nature of slamming events, which do not allow sufficient time for diffusion in the fluid domain. For the RANS simulations, motion of the wedge was achieved using the overset grid technique, whereby varying the discretising time step was found to have a pronounced impact on the accuracy of the captured slamming event. Through analysing the numerical data, one can observe that the RANS results correlate slightly better with the experimental data as opposed to that obtained from the SPH modelling. However, considering the robustness and quick set up of the SPH simulations, both of these two numerical approaches are considered to be promising tools for modelling more complicated slamming problems, including those potentially involving more intricate structures.
RANS based CFD methodology for a real scale 217-pin wire-wrapped fuel assembly of KAERI PGSFR
Energy Technology Data Exchange (ETDEWEB)
Jeong, Jae-Ho, E-mail: jhjeong@kaeri.re.kr [Korea Atomic Energy Research Institute, 989-111 Daedeok-daero, Yuseoung-gu, Daejeon (Korea, Republic of); Song, Min-Seop [Department of Nuclear Engineering, Seoul National University, 559 Gwanak-ro, Gwanak-gu, Seoul (Korea, Republic of); Lee, Kwi-Lim [Korea Atomic Energy Research Institute, 989-111 Daedeok-daero, Yuseoung-gu, Daejeon (Korea, Republic of)
2017-03-15
Highlights: • This paper presents a suitable way for a practical RANS based CFD methodology which is applicable to real scale 217-pin wire-wrapped fuel assembly of KAERI PGSFR. • A key point of differentiation of the RANS based CFD methodology in this study is adapting an innovative grid generation method using a fortran based in-house code with a GGI function in a general-purpose commercial CFD code, CFX. • The RANS based CFD methodology is implemented with high resolution scheme and SST turbulence model in the 7-pin 37-pin, and 127-pin wire-wrapped fuel assembly of PNC and JNC. Furthermore, the RANS based CFD methodology can be successfully extended to the real scale 217-pin wire-wrapped fuel bundles of KAERI PGSFR. • Three-dimensional thermal-hydraulic characteristics have been also investigated briefly. - Abstract: This paper presents a suitable way for a practical RANS (Reynolds Averaged Navier-Stokes simulation) based CFD (Computational Fluid Dynamics) methodology which is applicable to real scale 217-pin wire-wrapped fuel assembly of KAERI (Korea Atomic Energy Research Institute) PGSFR (Prototype Gen-IV Sodium-cooled Fast Reactor). The main purpose of the current study is to support license issue for the KAERI PGSFR core safety and to elucidate thermal-hydraulic characteristics in a 217-pin wire-wrapped fuel assembly of KAERI PGSFR. A key point of differentiation of the RANS based CFD methodology in this study is adapting an innovative grid generation method using a fortran based in-house code with a GGI (General Grid Interface) function in a general-purpose commercial CFD code, CFX. The innovative grid generation method with GGI function can achieve to simulate a real wire shape with minimizing cell skewness. The RANS based CFD methodology is implemented with high resolution scheme in convection term and SST (Shear Stress Transport) turbulence model in the 7-pin 37-pin, and 127-pin wire-wrapped fuel assembly of PNC (Power reactor and Nuclear fuel
RANS-based simulation of wave-induced sheet-flow transport of graded sediments
DEFF Research Database (Denmark)
Calistan, Ugur; Fuhrman, David R.
2017-01-01
A one-dimensional vertical (1DV) turbulence-closure flow model, coupled with sediment transport capabilities,is extended to incorporate graded sediment mixtures. The hydrodynamic model solves the horizontalcomponent of the incompressible Reynolds-averaged Navier–Stokes (RANS) equations coupled...... for each grain fraction, includingeffects associated with increased exposure of larger particles within a mixture. The suspended sedimenttransport model also makes use of modified reference concentration approach, wherein reference concentrationscomputed individually for each fraction are translated...... to a common level, conveniently enabling use of asingle computational grid for the simulation of suspended sediments. Parametric study shows that these twoeffects combine to help alleviate an otherwise systematic tendency towards over- (under-) predicted transportrates for fine (coarse) sand fractions...
Rans-Based Numerical Simulation of Wave-Induced Sheet-Flow Transport of Graded Sediments
DEFF Research Database (Denmark)
Fuhrman, David R.; Caliskan, Ugur
An existing one-dimensional vertical (1DV) turbulence-closure flow model, coupled with sediment transport capabilities, is extended to incorporate graded sediment mixtures. The hydrodynamic model solves the horizontal component of the incompressible Reynolds-averaged Navier–Stokes (RANS) equations...... coupled with k–ω turbulence closure. In addition to standard bed and suspended load descriptions, the sediment transport model incorporates so-called high-concentration effects (turbulence damping and hindered settling velocities). The sediment transport model treats the bed and suspended load...... individually for each grain fraction within a mixture, and includes effects associated with increased exposure of larger particles within a mixture. The model also makes use of a modified reference concentration approach, with reference concentrations computed individually for each fraction...
RANS-based simulation of turbulent wave boundary layer and sheet-flow sediment transport processes
DEFF Research Database (Denmark)
Fuhrman, David R.; Schløer, Signe; Sterner, Johanna
2013-01-01
A numerical model coupling the horizontal component of the incompressible Reynolds-averaged Navier–Stokes (RANS) equationswith two-equation k−ω turbulence closure is presented and used to simulate a variety of turbulent wave boundary layer processes. The hydrodynamic model is additionally coupled...... of a number of local factors important within cross-shore wave boundary layer and sediment transport dynamics. The hydrodynamic model is validated for both hydraulically smooth and rough conditions, based on wave friction factor diagrams and boundary layer streaming profiles, with the results in excellent...... agreement with experimental and/or previous numerical work. The sediment transport model is likewise validated against oscillatory tunnel experiments involving both velocity-skewed and acceleration-skewed flows, as well as against measurements beneath real progressive waves.Model capabilities are exploited...
Directory of Open Access Journals (Sweden)
Kwang-Jun Paik
2015-05-01
Full Text Available The wake characteristics of Contra-Rotating Propeller (CRP were investigated using numerical simulation and flow measurement. The numerical simulation was carried out with a commercial CFD code based on a Reynolds Averaged Navier-Stokes (RANS equations solver, and the flow measurement was performed with Stereoscopic Particle Image Velocimetry (SPIV system. The simulation results were validated through the comparison with the experiment results measured around the leading edge of rudder to investigate the effect of propeller operation under the conditions without propeller, with forward propeller alone, and with both forward and aft propellers. The evolution of CRP wake was analyzed through velocity and vorticity contours on three transverse planes and one longitudinal plane based on CFD results. The trajectories of propeller tip vortex core in the cases with and without aft propeller were also compared, and larger wake contraction with CRP was confirmed.
Directory of Open Access Journals (Sweden)
Kwang-Jun Paik
2013-12-01
Full Text Available Simulations of cavitation flow and hull pressure fluctuation for a marine propeller operating behind a hull using the unsteady Reynolds-Averaged Navier-Stokes equations (RANS are presented. A full hull body submerged under the free surface is modeled in the computational domain to simulate directly the wake field of the ship at the propeller plane. Simulations are performed in design and ballast draught conditions to study the effect of cavitation number. And two propellers with slightly different geometry are simulated to validate the detectability of the numerical simulation. All simulations are performed using a commercial CFD software FLUENT. Cavitation patterns of the simulations show good agreement with the experimental results carried out in Samsung CAvitation Tunnel (SCAT. The simulation results for the hull pressure fluctuation induced by a propeller are also compared with the experimental results showing good agreement in the tendency and amplitude, especially, for the first blade frequency.
Differential Reynolds stress modeling for separating flows in industrial aerodynamics
2015-01-01
This book presents recent progress in the application of RANS turbulence models based on the Reynolds stress transport equations. A variety of models has been implemented by different groups into different flow solvers and applied to external as well as to turbomachinery flows. Comparisons between the models allow an assessment of their performance in different flow conditions. The results demonstrate the general applicability of differential Reynolds stress models to separating flows in industrial aerodynamics.
RAN Translation in Huntington Disease.
Bañez-Coronel, Monica; Ayhan, Fatma; Tarabochia, Alex D; Zu, Tao; Perez, Barbara A; Tusi, Solaleh Khoramian; Pletnikova, Olga; Borchelt, David R; Ross, Christopher A; Margolis, Russell L; Yachnis, Anthony T; Troncoso, Juan C; Ranum, Laura P W
2015-11-18
Huntington disease (HD) is caused by a CAG ⋅ CTG expansion in the huntingtin (HTT) gene. While most research has focused on the HTT polyGln-expansion protein, we demonstrate that four additional, novel, homopolymeric expansion proteins (polyAla, polySer, polyLeu, and polyCys) accumulate in HD human brains. These sense and antisense repeat-associated non-ATG (RAN) translation proteins accumulate most abundantly in brain regions with neuronal loss, microglial activation and apoptosis, including caudate/putamen, white matter, and, in juvenile-onset cases, also the cerebellum. RAN protein accumulation and aggregation are length dependent, and individual RAN proteins are toxic to neural cells independent of RNA effects. These data suggest RAN proteins contribute to HD and that therapeutic strategies targeting both sense and antisense genes may be required for efficacy in HD patients. This is the first demonstration that RAN proteins are expressed across an expansion located in an open reading frame and suggests RAN translation may also contribute to other polyglutamine diseases. Copyright © 2015 Elsevier Inc. All rights reserved.
Performance evaluation of RANS-based turbulence models in simulating a honeycomb heat sink
Subasi, Abdussamet; Ozsipahi, Mustafa; Sahin, Bayram; Gunes, Hasan
2017-07-01
As well-known, there is not a universal turbulence model that can be used to model all engineering problems. There are specific applications for each turbulence model that make it appropriate to use, and it is vital to select an appropriate model and wall function combination that matches the physics of the problem considered. Therefore, in this study, performance of six well-known Reynolds-Averaged Navier-Stokes ( RANS) based turbulence models which are the Standard k {{-}} ɛ, the Renormalized Group k- ɛ, the Realizable k- ɛ, the Reynolds Stress Model, the k- ω and the Shear Stress Transport k- ω and accompanying wall functions which are the standard, the non-equilibrium and the enhanced are evaluated via 3D simulation of a honeycomb heat sink. The CutCell method is used to generate grid for the part including heat sink called test section while a hexahedral mesh is employed to discretize to inlet and outlet sections. A grid convergence study is conducted for verification process while experimental data and well-known correlations are used to validate the numerical results. Prediction of pressure drop along the test section, mean base plate temperature of the heat sink and temperature at the test section outlet are regarded as a measure of the performance of employed models and wall functions. The results indicate that selection of turbulence models and wall functions has a great influence on the results and, therefore, need to be selected carefully. Hydraulic and thermal characteristics of the honeycomb heat sink can be determined in a reasonable accuracy using RANS- based turbulence models provided that a suitable turbulence model and wall function combination is selected.
On the stagnation point anomaly of RANS
野村, 駿; 島, 信行; Takashi, NOMURA; Nobuyuki, SHIMA; 静大院; 静大工; Shizuoka Univ.
2010-01-01
In impinging flows, most Reynolds-averaged turbulence models severely overpredict the wall-normal turbulence intensity on the stagnation streamline (The stagnation point anomaly). In the present study, plane impinging flows are predicted using a second-moment closure which employs a stress redistribution model proposed by Shima and Kobayashi (2007) with an additional redistribution term. The closure dissolves the stagnation point anomaly in spite of a simple "standard" ε transport equation ad...
Energy Technology Data Exchange (ETDEWEB)
S. Dartevelle
2005-09-05
The objective of this manuscript is to fully derive a geophysical multiphase model able to ''accommodate'' different multiphase turbulence approaches; viz., the Reynolds Averaged Navier-Stokes (RANS), the Large Eddy Simulation (LES), or hybrid RANSLES. This manuscript is the first part of a larger geophysical multiphase project--lead by LANL--that aims to develop comprehensive modeling tools for large-scale, atmospheric, transient-buoyancy dusty jets and plume (e.g., plinian clouds, nuclear ''mushrooms'', ''supercell'' forest fire plumes) and for boundary-dominated geophysical multiphase gravity currents (e.g., dusty surges, diluted pyroclastic flows, dusty gravity currents in street canyons). LES is a partially deterministic approach constructed on either a spatial- or a temporal-separation between the large and small scales of the flow, whereas RANS is an entirely probabilistic approach constructed on a statistical separation between an ensemble-averaged mean and higher-order statistical moments (the so-called ''fluctuating parts''). Within this specific multiphase context, both turbulence approaches are built up upon the same phasic binary-valued ''function of presence''. This function of presence formally describes the occurrence--or not--of any phase at a given position and time and, therefore, allows to derive the same basic multiphase Navier-Stokes model for either the RANS or the LES frameworks. The only differences between these turbulence frameworks are the closures for the various ''turbulence'' terms involving the unknown variables from the fluctuating (RANS) or from the subgrid (LES) parts. Even though the hydrodynamic and thermodynamic models for RANS and LES have the same set of Partial Differential Equations, the physical interpretations of these PDEs cannot be the same, i.e., RANS models an averaged field, while LES simulates a
RAN GTPase and Osteopontin in Pancreatic Cancer.
Saxena, Shivam; Gandhi, Ankit; Lim, Pei-Wen; Relles, Daniel; Sarosiek, Konrad; Kang, Christopher; Chipitsyna, Galina; Sendecki, Jocelyn; Yeo, Charles J; Arafat, Hwyda A
2013-04-01
Pancreatic ductal adenocarcinoma (PDA) has the worst prognosis among cancers, mainly due to the high incidence of early metastases. RAN small GTPase (RAN) is a protein that plays physiological roles in the regulation of nuclear transport and microtubule spindle assembly. RAN was recently shown to mediate the invasive functions of the prometastatic protein osteopontin (OPN) in breast cancer cells. We and others have shown previously that high levels of OPN are present in PDA. In this study, we analyzed the expression and correlation of RAN with OPN in human pancreatic lesions, and explored their regulation in PDA cell lines. Real time PCR was used to analyze RAN and OPN mRNA levels in PDA, adjacent non-malignant, and benign pancreatic tissues. Expression levels were correlated with survival and different clinicopathological parameters using different statistical methods. Transient transfection studies using OPN and RAN plasmids, and knockdown experiments using siRNA were used to examine their mutual regulation. OPN and RAN levels highly correlated with each other (pobesity, T stage, BMI, or survival. However, we found a significant association between RAN levels and perineural invasion (HR=0.79, 95% CI 0.59, 1.07; p=0.0378.). OPN and RAN colocalized in PDA tissues and cell lines. Increasing RAN expression in PDA cells induced OPN transcription and RAN silencing reduced total OPN levels. OPN did not have any significant effect on RAN transcription. The high levels of RAN in PDA and its correlation with OPN and with perineural invasion suggest that RAN may contribute to PDA metastasis and progression through the induction of OPN. RAN's role in the regulation of OPN in PDA is unique and could provide potential novel therapeutic strategies to combat PDA aggressiveness.
Optimal fluxes and Reynolds stresses
Jimenez, Javier
2016-01-01
It is remarked that fluxes in conservation laws, such as the Reynolds stresses in the momentum equation of turbulent shear flows, or the spectral energy flux in isotropic turbulence, are only defined up to an arbitrary solenoidal field. While this is not usually significant for long-time averages, it becomes important when fluxes are modelled locally in large-eddy simulations, or in the analysis of intermittency and cascades. As an example, a numerical procedure is introduced to compute fluxes in scalar conservation equations in such a way that their total integrated magnitude is minimised. The result is an irrotational vector field that derives from a potential, thus minimising sterile flux `circuits'. The algorithm is generalised to tensor fluxes and applied to the transfer of momentum in a turbulent channel. The resulting instantaneous Reynolds stresses are compared with their traditional expressions, and found to be substantially different.
Westra, Doug G.; West, Jeffrey S.; Richardson, Brian R.
2015-01-01
Historically, the analysis and design of liquid rocket engines (LREs) has relied on full-scale testing and one-dimensional empirical tools. The testing is extremely expensive and the one-dimensional tools are not designed to capture the highly complex, and multi-dimensional features that are inherent to LREs. Recent advances in computational fluid dynamics (CFD) tools have made it possible to predict liquid rocket engine performance, stability, to assess the effect of complex flow features, and to evaluate injector-driven thermal environments, to mitigate the cost of testing. Extensive efforts to verify and validate these CFD tools have been conducted, to provide confidence for using them during the design cycle. Previous validation efforts have documented comparisons of predicted heat flux thermal environments with test data for a single element gaseous oxygen (GO2) and gaseous hydrogen (GH2) injector. The most notable validation effort was a comprehensive validation effort conducted by Tucker et al. [1], in which a number of different groups modeled a GO2/GH2 single element configuration by Pal et al [2]. The tools used for this validation comparison employed a range of algorithms, from both steady and unsteady Reynolds Averaged Navier-Stokes (U/RANS) calculations, large-eddy simulations (LES), detached eddy simulations (DES), and various combinations. A more recent effort by Thakur et al. [3] focused on using a state-of-the-art CFD simulation tool, Loci/STREAM, on a two-dimensional grid. Loci/STREAM was chosen because it has a unique, very efficient flamelet parameterization of combustion reactions that are too computationally expensive to simulate with conventional finite-rate chemistry calculations. The current effort focuses on further advancement of validation efforts, again using the Loci/STREAM tool with the flamelet parameterization, but this time with a three-dimensional grid. Comparisons to the Pal et al. heat flux data will be made for both RANS and
Efthimiou, G. C.; Andronopoulos, S.; Bartzis, J. G.
2018-02-01
One of the key issues of recent research on the dispersion inside complex urban environments is the ability to predict dosage-based parameters from the puff release of an airborne material from a point source in the atmospheric boundary layer inside the built-up area. The present work addresses the question of whether the computational fluid dynamics (CFD)-Reynolds-averaged Navier-Stokes (RANS) methodology can be used to predict ensemble-average dosage-based parameters that are related with the puff dispersion. RANS simulations with the ADREA-HF code were, therefore, performed, where a single puff was released in each case. The present method is validated against the data sets from two wind-tunnel experiments. In each experiment, more than 200 puffs were released from which ensemble-averaged dosage-based parameters were calculated and compared to the model's predictions. The performance of the model was evaluated using scatter plots and three validation metrics: fractional bias, normalized mean square error, and factor of two. The model presented a better performance for the temporal parameters (i.e., ensemble-average times of puff arrival, peak, leaving, duration, ascent, and descent) than for the ensemble-average dosage and peak concentration. The majority of the obtained values of validation metrics were inside established acceptance limits. Based on the obtained model performance indices, the CFD-RANS methodology as implemented in the code ADREA-HF is able to predict the ensemble-average temporal quantities related to transient emissions of airborne material in urban areas within the range of the model performance acceptance criteria established in the literature. The CFD-RANS methodology as implemented in the code ADREA-HF is also able to predict the ensemble-average dosage, but the dosage results should be treated with some caution; as in one case, the observed ensemble-average dosage was under-estimated slightly more than the acceptance criteria. Ensemble-average
Efthimiou, G. C.; Andronopoulos, S.; Bartzis, J. G.
2017-02-01
One of the key issues of recent research on the dispersion inside complex urban environments is the ability to predict dosage-based parameters from the puff release of an airborne material from a point source in the atmospheric boundary layer inside the built-up area. The present work addresses the question of whether the computational fluid dynamics (CFD)-Reynolds-averaged Navier-Stokes (RANS) methodology can be used to predict ensemble-average dosage-based parameters that are related with the puff dispersion. RANS simulations with the ADREA-HF code were, therefore, performed, where a single puff was released in each case. The present method is validated against the data sets from two wind-tunnel experiments. In each experiment, more than 200 puffs were released from which ensemble-averaged dosage-based parameters were calculated and compared to the model's predictions. The performance of the model was evaluated using scatter plots and three validation metrics: fractional bias, normalized mean square error, and factor of two. The model presented a better performance for the temporal parameters (i.e., ensemble-average times of puff arrival, peak, leaving, duration, ascent, and descent) than for the ensemble-average dosage and peak concentration. The majority of the obtained values of validation metrics were inside established acceptance limits. Based on the obtained model performance indices, the CFD-RANS methodology as implemented in the code ADREA-HF is able to predict the ensemble-average temporal quantities related to transient emissions of airborne material in urban areas within the range of the model performance acceptance criteria established in the literature. The CFD-RANS methodology as implemented in the code ADREA-HF is also able to predict the ensemble-average dosage, but the dosage results should be treated with some caution; as in one case, the observed ensemble-average dosage was under-estimated slightly more than the acceptance criteria. Ensemble-average
Tuning a RANS k-e model for jet-in-crossflow simulations.
Energy Technology Data Exchange (ETDEWEB)
Lefantzi, Sophia; Ray, Jaideep; Arunajatesan, Srinivasan; DeChant, Lawrence Justin
2013-09-01
We develop a novel calibration approach to address the problem of predictive ke RANS simulations of jet-incrossflow. Our approach is based on the hypothesis that predictive ke parameters can be obtained by estimating them from a strongly vortical flow, specifically, flow over a square cylinder. In this study, we estimate three ke parameters, C%CE%BC, Ce2 and Ce1 by fitting 2D RANS simulations to experimental data. We use polynomial surrogates of 2D RANS for this purpose. We conduct an ensemble of 2D RANS runs using samples of (C%CE%BC;Ce2;Ce1) and regress Reynolds stresses to the samples using a simple polynomial. We then use this surrogate of the 2D RANS model to infer a joint distribution for the ke parameters by solving a Bayesian inverse problem, conditioned on the experimental data. The calibrated (C%CE%BC;Ce2;Ce1) distribution is used to seed an ensemble of 3D jet-in-crossflow simulations. We compare the ensemble's predictions of the flowfield, at two planes, to PIV measurements and estimate the predictive skill of the calibrated 3D RANS model. We also compare it against 3D RANS predictions using the nominal (uncalibrated) values of (C%CE%BC;Ce2;Ce1), and find that calibration delivers a significant improvement to the predictive skill of the 3D RANS model. We repeat the calibration using surrogate models based on kriging and find that the calibration, based on these more accurate models, is not much better that those obtained with simple polynomial surrogates. We discuss the reasons for this rather surprising outcome.
RANS Modeling of Stably Stratified Turbulent Boundary Layer Flows in OpenFOAM®
Directory of Open Access Journals (Sweden)
Wilson Jordan M.
2015-01-01
Full Text Available Quantifying mixing processes relating to the transport of heat, momentum, and scalar quantities of stably stratified turbulent geophysical flows remains a substantial task. In a stably stratified flow, such as the stable atmospheric boundary layer (SABL, buoyancy forces have a significant impact on the flow characteristics. This study investigates constant and stability-dependent turbulent Prandtl number (Prt formulations linking the turbulent viscosity (νt and diffusivity (κt for modeling applications of boundary layer flows. Numerical simulations of plane Couette flow and pressure-driven channel flow are performed using the Reynolds-averaged Navier-Stokes (RANS framework with the standard k-ε turbulence model. Results are compared with DNS data to evaluate model efficacy for predicting mean velocity and density fields. In channel flow simulations, a Prandtl number formulation for wall-bounded flows is introduced to alleviate overmixing of the mean density field. This research reveals that appropriate specification of Prt can improve predictions of stably stratified turbulent boundary layer flows.
Simulation of an Isolated Tiltrotor in Hover with an Unstructured Overset-Grid RANS Solver
Lee-Rausch, Elizabeth M.; Biedron, Robert T.
2009-01-01
An unstructured overset-grid Reynolds Averaged Navier-Stokes (RANS) solver, FUN3D, is used to simulate an isolated tiltrotor in hover. An overview of the computational method is presented as well as the details of the overset-grid systems. Steady-state computations within a noninertial reference frame define the performance trends of the rotor across a range of the experimental collective settings. Results are presented to show the effects of off-body grid refinement and blade grid refinement. The computed performance and blade loading trends show good agreement with experimental results and previously published structured overset-grid computations. Off-body flow features indicate a significant improvement in the resolution of the first perpendicular blade vortex interaction with background grid refinement across the collective range. Considering experimental data uncertainty and effects of transition, the prediction of figure of merit on the baseline and refined grid is reasonable at the higher collective range- within 3 percent of the measured values. At the lower collective settings, the computed figure of merit is approximately 6 percent lower than the experimental data. A comparison of steady and unsteady results show that with temporal refinement, the dynamic results closely match the steady-state noninertial results which gives confidence in the accuracy of the dynamic overset-grid approach.
Tackling complex turbulent flows with transient RANS
Kenjeres, S.; Hanjalic, K.
2009-01-01
This article reviews some recent applications of the transient-Reynoldsaveraged Navier–Stokes (T-RANS) approach in simulating complex turbulent flows dominated by externally imposed body forces, primarily by thermal buoyancy and the Lorentz force. The T-RANS aims at numerical resolving unsteady
Development of a Hybrid RANS/LES Method for Turbulent Mixing Layers
Georgiadis, Nicholas J.; Alexander, J. Iwan D.; Reshotko, Eli
2001-01-01
Significant research has been underway for several years in NASA Glenn Research Center's nozzle branch to develop advanced computational methods for simulating turbulent flows in exhaust nozzles. The primary efforts of this research have concentrated on improving our ability to calculate the turbulent mixing layers that dominate flows both in the exhaust systems of modern-day aircraft and in those of hypersonic vehicles under development. As part of these efforts, a hybrid numerical method was recently developed to simulate such turbulent mixing layers. The method developed here is intended for configurations in which a dominant structural feature provides an unsteady mechanism to drive the turbulent development in the mixing layer. Interest in Large Eddy Simulation (LES) methods have increased in recent years, but applying an LES method to calculate the wide range of turbulent scales from small eddies in the wall-bounded regions to large eddies in the mixing region is not yet possible with current computers. As a result, the hybrid method developed here uses a Reynolds-averaged Navier-Stokes (RANS) procedure to calculate wall-bounded regions entering a mixing section and uses a LES procedure to calculate the mixing-dominated regions. A numerical technique was developed to enable the use of the hybrid RANS-LES method on stretched, non-Cartesian grids. With this technique, closure for the RANS equations is obtained by using the Cebeci-Smith algebraic turbulence model in conjunction with the wall-function approach of Ota and Goldberg. The LES equations are closed using the Smagorinsky subgrid scale model. Although the function of the Cebeci-Smith model to replace all of the turbulent stresses is quite different from that of the Smagorinsky subgrid model, which only replaces the small subgrid turbulent stresses, both are eddy viscosity models and both are derived at least in part from mixing-length theory. The similar formulation of these two models enables the RANS
Carlos Roberto Ilário da Silva
2011-01-01
Uma nova ferramenta de aeroacústica computacional baseada em simulações RANS (Reynolds Averaged Navier-Stokes) foi desenvolvida para a predição do ruído gerado pelo escoamento tri-dimensional de jatos complexos. O método é denominado de LRT o qual surgiu da combinação da analogia acústica de Lighthill com o método de acústica geométrica Ray-Tracing. A grande vantagem da utilização do método LRT para predições de ruído é que este determina não apenas as fontes sonoras presentes...
The Ran pathway in Drosophila melanogaster mitosis
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James G Wakefield
2015-11-01
Full Text Available Over the last two decades, the small GTPase Ran has emerged as a central regulator of both mitosis and meiosis, particularly in the generation, maintenance and regulation of the microtubule (MT-based bipolar spindle. Ran-regulated pathways in mitosis bear many similarities to the well-characterized functions of Ran in nuclear transport and, as with transport, the majority of these mitotic effects are mediated through affecting the physical interaction between karyopherins and Spindle Assembly Factors (SAFs - a loose term describing proteins or protein complexes involved in spindle assembly through promoting nucleation, stabilization, and/or depolymerization of MTs, through anchoring MTs to specific structures such as centrosomes, chromatin or kinetochores, or through sliding MTs along each other to generate the force required to achieve bipolarity. As such, the Ran-mediated pathway represents a crucial functional module within the wider spindle assembly landscape. Research into mitosis using the model organism Drosophila melanogaster has contributed substantially to our understanding of centrosome and spindle function. However, in comparison to mammalian systems, very little is known about the contribution of Ran-mediated pathways in Drosophila mitosis. This article sets out to summarize our understanding of the roles of the Ran pathway components in Drosophila mitosis, focusing on the syncytial blastoderm embryo, arguing that, far from being superfluous, it can provide important insights into the conserved functions on Ran during spindle formation.
Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene.
Fauser, S.; Aslanukov, A.; Roepman, R.; Ferreira, P.A.
2001-01-01
The Ran-binding protein 2 (RanBP2) is a giant scaffold and mosaic cyclophilin-related nucleoporin implicated in the Ran-GTPase cycle. There are no orthologs of the RanBP2 gene in yeast and Drosophila genomes. In humans, this bona fide gene is partially duplicated in a RanBP2 gene cluster and lies in
Energy Technology Data Exchange (ETDEWEB)
Benhamadouche, Sofiane, E-mail: sofiane.benhamadouche@edf.fr
2017-02-15
Highlights: • The paper deals with the use of (U)RANS and LES in nuclear engineering applications. • It gives some ideas and guidelines to run high quality computations. • Some perspectives are drawn concerning the development of (U)RANS and LES approaches in the future. - Abstract: The present paper gives some ideas and guidelines in order to run high quality (U)RANS or LES computations. The paper starts with (U)RANS approaches, advocating the use of Reynolds Stress Models for complex flows and recommending further work on modeling of turbulent heat fluxes, which remains today too basic in industry. The superiority of wall-resolved models vs. wall-modeled in RANS is recalled and the use of adaptive wall treatment is suggested. The concept of Unsteady RANS is finally questioned. Then, important issues around LES are raised. The mesh refinement criteria are recalled for wall-resolved LES and the use of wall models addressed. The production of DNS and wall-resolved LES calculations for flow understanding and RANS validation is encouraged.
1985-02-01
of the blade . The Darrieus VAWT has more complex aerodynamics. This type of wind turbine produces power as a result of the tangential thrust as... Wind turbine blades also require high aerodynamic efficiency and all-weather capabilities. The need for efficient low Reynolds number airfoils which...application. The design of this type of propeller is similar to the design of low solidity wind turbine blades and will be discussed in the next
Effect of Reynolds Number on Aerodynamics of Airfoil with Gurney Flap
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Shubham Jain
2015-01-01
Full Text Available Steady state, two-dimensional computational investigations performed on NACA 0012 airfoil to analyze the effect of variation in Reynolds number on the aerodynamics of the airfoil without and with a Gurney flap of height of 3% chord are presented in this paper. RANS based one-equation Spalart-Allmaras model is used for the computations. Both lift and drag coefficients increase with Gurney flap compared to those without Gurney flap at all Reynolds numbers at all angles of attack. The zero lift angle of attack seems to become more negative as Reynolds number increases due to effective increase of the airfoil camber. However the stall angle of attack decreased by 2° for the airfoil with Gurney flap. Lift coefficient decreases rapidly and drag coefficient increases rapidly when Reynolds number is decreased below critical range. This occurs due to change in flow pattern near Gurney flap at low Reynolds numbers.
Nichino, Takafumi; Hahn, Seonghyeon; Shariff, Karim
2010-01-01
This slide presentation reviews the Large Eddy Simulation of a high reynolds number Coanda flow that is separated from a round trailing edge of a ciruclation control airfoil. The objectives of the study are: (1) To investigate detailed physics (flow structures and statistics) of the fully turbulent Coanda jet applied to a CC airfoil, by using LES (2) To compare LES and RANS results to figure out how to improve the performance of existing RANS models for this type of flow.
Mesh Generation and Adaption for High Reynolds Number RANS Computations Project
National Aeronautics and Space Administration — The innovation of our Phase II STTR program is to develop and provide to NASA automatic mesh generation software for the simulation of fluid flows using...
Energy Technology Data Exchange (ETDEWEB)
Carasik, Lane B.; Shaver, Dillon R.; Hassan, Yassin A.; Haefner, Jonah B.
2017-11-01
The development of molten salt cooled reactors (MSR) and fluoride-salt cooled high temperature reactors (FHR) requires the use of advanced design tools for the primary heat exchanger design. Due to geometric and flow characteristics, compact (pitch to diameter ratios equal to or less than 1.25) heat exchangers with a crossflow flow arrangement can become desirable for these reactors. Unfortunately, the available experimental data is limited for compact tube bundles or banks in crossflow. Computational Fluid Dynamics can be used to alleviate the lack of experimental data in these tube banks. Previous computational efforts have been primarily focused on large S/D ratios (larger than 1.4) using unsteady Reynolds averaged Navier-Stokes and Large Eddy Simulation frameworks. These approaches are useful, but have large computational requirements that make comprehensive design studies impractical. A CFD study was conducted with steady RANS in an effort to provide a starting point for future design work. The study was performed for an in-line tube bank geometry with FLiBe (LiF-BeF2), a frequently selected molten salt, as the working fluid. Based on the estimated pressure drops, the pressure and velocity distributions in the domain, an appropriate meshing strategy was determined and presented. Periodic boundaries in the spanwise direction transverse flow were determined to be an appropriate boundary condition for reduced computational domains. The domain size was investigated and a minimum of 2-flow channels for a domain is recommended to ensure the behavior is accounted for. Lastly, the standard low Re κ-ε (Lien) turbulence model was determined to be the most appropriate for steady RANS of this case at the time of writing.
Analogies between Mass-Flux and Reynolds-Averaged Equations
Roode, S.R. de; Duynkerke, P.G.
2000-01-01
In many large-scale models mass-flux parameterizations are applied to prognose the effect of cumulus cloud convection on the large-scale environment. Key parameters in the mass-flux equations are the lateral entrainment and detrainment rates. The physical meaning of these parameters is that they
Hybrid RANS/LES method for wind flow over complex terrain
DEFF Research Database (Denmark)
Bechmann, Andreas; Sørensen, Niels N.
2010-01-01
), and this layer acts as wall model for the outer flow handled by LES. The well-known high Reynolds number two-equation k - turbulence model is used in the RANS layer and the model automatically switches to a two-equation k - subgrid scale stress model in the LES region. The approach can be used for flow over...... the turbulent kinetic energy, whereas the new method captures the high turbulence levels well but underestimates the mean velocity. The presented results are for a relative mild configuration of complex terrain, but the proposed method can also be used for highly complex terrain where the benefits of the new...
Prospathopoulos, John M.; Papadakis, Giorgos; Sieros, Giorgos; Voutsinas, Spyros G.; Chaviaropoulos, Takis K.; Diakakis, Kostas
2014-06-01
The aerodynamic characteristics of thick airfoils in high Reynolds number is assessed using two different CFD RANS solvers: the compressible MaPFlow and the incompressible CRES-flowNS-2D both equipped with the k-ω SST turbulence model. Validation is carried out by comparing simulations against existing high Reynolds experimental data for the NACA 63-018 airfoil in the range of -10° to 20°. The use of two different solvers aims on one hand at increasing the credibility in the results and on the other at quantifying the compressibility effects. Convergence of steady simulations is achieved within a mean range of -10° to 14° which refers to attached or light stall conditions. Over this range the simulations from the two codes are in good agreement. As stall gets deeper, steady convergence ceases and the simulations must switch to unsteady. Lift and drag oscillations are produced which increase in amplitude as the angle of attack increases. Finally in post stall, the average CL is found to decrease up to ~24° or 32° for the FFA or the NACA 63-018 airfoils respectively, and then recover to higher values indicating a change in the unsteady features of the flow.
An Enhanced OFDM Resource Allocation Algorithm in C-RAN Based 5G Public Safety Network
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Lei Feng
2016-01-01
Full Text Available Public Safety Network (PSN is the network for critical communication when disaster occurs. As a key technology in 5G, Cloud-Radio Access Network (C-RAN can play an important role in PSN instead of LTE-based RAN. This paper firstly introduces C-RAN based PSN architecture and models the OFDM resource allocation problem in C-RAN based PSN as an integer quadratic programming, which allows the trade-off between expected bitrates and allocating fairness of PSN Service User (PSU. However, C-RAN based PSN needs to improve the efficiency of allocating algorithm because of a mass of PSU-RRH associations when disaster occurs. To deal with it, the resources allocating problem with integer variables is relaxed into one with continuous variables in the first step and an algorithm based on Generalized Bender’s Decomposition (GBD is proposed to solve it. Then we use Feasible Pump (FP method to get a feasible integer solution on the original OFDM resources allocation problem. The final experiments show the total throughput achieved by C-RAN based PSN is at most higher by 19.17% than the LTE-based one. And the average computational time of the proposed GBD and FP algorithm is at most lower than Barrier by 51.5% and GBD with no relaxation by 30.1%, respectively.
Numerical simulation of 3D backward facing step flows at various Reynolds numbers
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Louda Petr
2015-01-01
Full Text Available The work deals with the numerical simulation of 3D turbulent flow over backward facing step in a narrow channel. The mathematical model is based on the RANS equations with an explicit algebraic Reynolds stress model (EARSM. The numerical method uses implicit finite volume upwind discretization. While the eddy viscosity models fail in predicting complex 3D flows, the EARSM model is shown to provide results which agree well with experimental PIV data. The reference experimental data provide the 3D flow field. The simulations are compared with experiment for 3 values of Reynolds number.
Chromosomal association of Ran during meiotic and mitotic divisions.
Hinkle, Beth; Slepchenko, Boris; Rolls, Melissa M; Walther, Tobias C; Stein, Pascal A; Mehlmann, Lisa M; Ellenberg, Jan; Terasaki, Mark
2002-12-01
Recent studies in Xenopus egg extracts indicate that the small G protein Ran has a central role in spindle assembly and nuclear envelope reformation. We determined Ran localization and dynamics in cells during M phase. By immunofluorescence, Ran is accumulated on the chromosomes of meiosis-II-arrested Xenopus eggs. In living cells, fluorescently labeled Ran associated with the chromosomes in Xenopus and remained associated during anaphase when eggs were artificially activated. Fluorescent Ran associated with chromosomes in mouse eggs, during meiotic maturation and early embryonic divisions in starfish, and to a lesser degree during mitosis of a cultured mammalian cell line. Chromosomal Ran undergoes constant flux. From photobleach experiments in immature starfish oocytes, chromosomal Ran has a k(off) of approximately 0.06 second(-1), and binding analysis suggests that there is a single major site. The chromosomal interactions may serve to keep Ran-GTP in the vicinity of the chromosomes for spindle assembly and nuclear envelope reformation.
Data-free and data-driven spectral perturbations for RANS UQ
Edeling, Wouter; Mishra, Aashwin; Iaccarino, Gianluca
2017-11-01
Despite recent developments in high-fidelity turbulent flow simulations, RANS modeling is still vastly used by industry, due to its inherent low cost. Since accuracy is a concern in RANS modeling, model-form UQ is an essential tool for assessing the impacts of this uncertainty on quantities of interest. Applying the spectral decomposition to the modeled Reynolds-Stress Tensor (RST) allows for the introduction of decoupled perturbations into the baseline intensity (kinetic energy), shape (eigenvalues), and orientation (eigenvectors). This constitutes a natural methodology to evaluate the model form uncertainty associated to different aspects of RST modeling. In a predictive setting, one frequently encounters an absence of any relevant reference data. To make data-free predictions with quantified uncertainty we employ physical bounds to a-priori define maximum spectral perturbations. When propagated, these perturbations yield intervals of engineering utility. High-fidelity data opens up the possibility of inferring a distribution of uncertainty, by means of various data-driven machine-learning techniques. We will demonstrate our framework on a number of flow problems where RANS models are prone to failure. This research was partially supported by the Defense Advanced Research Projects Agency under the Enabling Quantification of Uncertainty in Physical Systems (EQUiPS) project (technical monitor: Dr Fariba Fahroo), and the DOE PSAAP-II program.
Modelling of sand transport under wave-generated sheet flows with a RANS diffusion model
Hassan, Wael; Ribberink, Jan S.
2010-01-01
A 1DV-RANS diffusion model is used to study sand transport processes in oscillatory flat-bed/sheet flow conditions. The central aim is the verification of the model with laboratory data and to identify processes controlling the magnitude and direction (‘onshore’/‘offshore’) of the net time-averaged
U.S. Department of Health & Human Services — A list of a variety of averages for each state or territory as well as the national average, including each quality measure, staffing, fine amount and number of...
Directory of Open Access Journals (Sweden)
D. A. Lyubimov
2015-01-01
Full Text Available Cavities often found in airplanes: a niche for the landing gear, various weapons, etc. Reducing fluctuations of pressure and temperature in the cavity is a relevant practical problem. The article presents simulation results of external subsonic flow around the cavity (M = 0.85, T = 300K. . Calculations were performed using the high-resolution RANS/ILES (Reynolds Averaged Navier-Stokes - RANS, Implicit Large Eddy Simulation - ILES method. To control flow the authors propose to use synthetic jets. Synthetic jets are produced by periodic ejection and suction of fluid from a slot induced by the movement of a diaphragm (generator of synthetic jets inside a cavity. They are compact and efficient and do not require a special working body and the ways for its supply. Instead of calculating the flow in the synthetic jet generator was used the modified boundary condition on the wall where the output slots was positioned. Under consideration there were two variants of slots for synthetic jets output: in front of the cavity and inside the cavity on the front wall. The frequency and amplitude values of the synthetic jet specified a mode of each jet. For a jet inside the cavity two modes have been reviewed, namely: 100 Hz and 50m/s, 200Hz and 50m/s. For jet in front of the cavity three modes have been reviewed, specifically: 20Hz and 20m/s, 100Hz and 50m/s, 200Hz and 50m/s. Analysis of calculation results showed that for all modes under examination, the synthetic jets reduced fluctuation of static pressure and temperature on the bottom and back walls of the cavity. The mode with parameters 200Hz, 50 m/s and synthetic jet located in front of the cavity was the most efficient. Furthermore, we compared the results of calculations for two-and three-dimensional cavities, which have the same length and depth. Research has shown that the simplified quasi-two-dimensional calculations cannot be used to evaluate the pressure and temperature fluctuations. This is due to
Verma, Sudeep; Dewan, Anupam
2018-01-01
The Partially-Averaged Navier-Stokes (PANS) approach has been applied for the first time to model turbulent flow and heat transfer in an ideal Czochralski set up with the realistic boundary conditions. This method provides variable level of resolution ranging from the Reynolds-Averaged Navier-Stokes (RANS) modelling to Direct Numerical Simulation (DNS) based on the filter control parameter. For the present case, a low-Re PANS model has been developed for Czochralski melt flow, which includes the effect of coriolis, centrifugal, buoyant and surface tension induced forces. The aim of the present study is to assess improvement in results on switching to PANS modelling from unsteady RANS (URANS) approach on the same computational mesh. The PANS computed results were found to be in good agreement with the reported experimental, DNS and Large Eddy Simulation (LES) data. A clear improvement in computational accuracy is observed in switching from the URANS approach to the PANS methodology. The computed results further improved with a reduction in the PANS filter width. Further the capability of the PANS model to capture key characteristics of the Czochralski crystal growth is also highlighted. It was observed that the PANS model was able to resolve the three-dimensional turbulent nature of the melt, characteristic flow structures arising due to flow instabilities and generation of thermal plumes and vortices in the Czochralski melt.
Kim, Soo-Hwan; Roux, Stanley J.
2003-01-01
Ran-binding proteins (RanBPs) are a group of proteins that bind to Ran (Ras-related nuclear small GTP-binding protein), and thus either control the GTP/GDP-bound states of Ran or help couple the Ran GTPase cycle to a cellular process. AtRanBP1c is a Ran-binding protein from Arabidopsis thaliana (L.) Heynh. that was recently shown to be critically involved in the regulation of auxin-induced mitotic progression [S.-H. Kim et al. (2001) Plant Cell 13:2619-2630]. Here we report that AtRanBP1c inhibits the EDTA-induced release of GTP from Ran and serves as a co-activator of Ran-GTPase-activating protein (RanGAP) in vitro. Transient expression of AtRanBP1c fused to a beta-glucuronidase (GUS) reporter reveals that the protein localizes primarily to the cytosol. Neither the N- nor C-terminus of AtRanBP1c, which flank the Ran-binding domain (RanBD), is necessary for the binding of PsRan1-GTP to the protein, but both are needed for the cytosolic localization of GUS-fused AtRanBP1c. These findings, together with a previous report that AtRanBP1c is critically involved in root growth and development, imply that the promotion of GTP hydrolysis by the Ran/RanGAP/AtRanBP1c complex in the cytoplasm, and the resulting concentration gradient of Ran-GDP to Ran-GTP across the nuclear membrane could be important in the regulation of auxin-induced mitotic progression in root tips of A. thaliana.
Markley, F. Landis; Cheng, Yang; Crassidis, John L.; Oshman, Yaakov
2007-01-01
Many applications require an algorithm that averages quaternions in an optimal manner. For example, when combining the quaternion outputs of multiple star trackers having this output capability, it is desirable to properly average the quaternions without recomputing the attitude from the the raw star tracker data. Other applications requiring some sort of optimal quaternion averaging include particle filtering and multiple-model adaptive estimation, where weighted quaternions are used to determine the quaternion estimate. For spacecraft attitude estimation applications, derives an optimal averaging scheme to compute the average of a set of weighted attitude matrices using the singular value decomposition method. Focusing on a 4-dimensional quaternion Gaussian distribution on the unit hypersphere, provides an approach to computing the average quaternion by minimizing a quaternion cost function that is equivalent to the attitude matrix cost function Motivated by and extending its results, this Note derives an algorithm that deterniines an optimal average quaternion from a set of scalar- or matrix-weighted quaternions. Rirthermore, a sufficient condition for the uniqueness of the average quaternion, and the equivalence of the mininiization problem, stated herein, to maximum likelihood estimation, are shown.
Flow field analysis of a pentagonal-shaped bridge deck by unsteady RANS
Directory of Open Access Journals (Sweden)
Md. Naimul Haque
2016-01-01
Full Text Available Long-span cable-stayed bridges are susceptible to dynamic wind effects due to their inherent flexibility. The fluid flow around the bridge deck should be well understood for the efficient design of an aerodynamically stable long-span bridge system. In this work, the aerodynamic features of a pentagonal-shaped bridge deck are explored numerically. The analytical results are compared with past experimental work to assess the capability of two-dimensional unsteady RANS simulation for predicting the aerodynamic features of this type of deck. The influence of the bottom plate slope on aerodynamic response and flow features was investigated. By varying the Reynolds number (2 × 104 to 20 × 104 the aerodynamic behavior at high wind speeds is clarified.
The Anatomy of the RAN-Reading Relationship
Georgiou, George K.; Parrila, Rauno; Papadopoulos, Timothy C.
2016-01-01
The purpose of this study was to contrast three models of the RAN-reading relationship derived from the most prominent theoretical accounts of how RAN is related to reading: the phonological processing, the orthographic processing and the speed of processing accounts. Grade 4 Greek-speaking children (n = 208; 114 girls, 94 boys; mean…
Prytz, Erik R.; Huuse, Øyvind; Müller, Bernhard; Bartl, Jan; Sætran, Lars Roar
2017-07-01
Turbulent flow at Reynolds numbers 5 . 104 to 106 around the NREL S826 airfoil used for wind turbine blades is simulated using delayed detached eddy simulation (DDES). The 3D domain is built as a replica of the low speed wind tunnel at the Norwegian University of Science and Technology (NTNU) with the wind tunnel walls considered as slip walls. The subgrid turbulent kinetic energy is used to model the sub-grid scale in the large eddy simulation (LES) part of DDES. Different Reynoldsaveraged Navier-Stokes (RANS) models are tested in ANSYS Fluent. The realizable k - ∈ model as the RANS model in DDES is found to yield the best agreement of simulated pressure distributions with the experimental data both from NTNU and the Technical University of Denmark (DTU), the latter for a shorter spanwise domain. The present DDES results are in excellent agreement with LES results from DTU. Since DDES requires much fewer cells in the RANS region near the wing surface than LES, DDES is computationally much more efficient than LES. Whereas DDES is able to predict lift and drag in close agreement with experiment up to stall, pure 2D RANS simulations fail near stall. After testing different numerical settings, time step sizes and grids for DDES, a Reynolds number study is conducted. Near stall, separated flow structures, so-called stall cells, are observed in the DDES results.
2011-09-02
... Employment and Training Administration Reynolds Food Packaging LLC, a Subsidiary of Reynolds Group Holding... Reynolds Food Packaging LLC, a subsidiary of Reynolds Group Holding Limited, Grove City, Pennsylvania... make the following certification: All workers of Reynolds Food Packaging LLC, a subsidiary of Reynolds...
Ritterhoff, Tobias; Das, Hrishikesh; Hofhaus, Götz; Schröder, Rasmus R; Flotho, Annette; Melchior, Frauke
2016-05-10
Continuous cycles of nucleocytoplasmic transport require disassembly of transport receptor/Ran-GTP complexes in the cytoplasm. A basic disassembly mechanism in all eukaryotes depends on soluble RanGAP and RanBP1. In vertebrates, a significant fraction of RanGAP1 stably interacts with the nucleoporin RanBP2 at a binding site that is flanked by FG-repeats and Ran-binding domains, and overlaps with RanBP2's SUMO E3 ligase region. Here, we show that the RanBP2/RanGAP1*SUMO1/Ubc9 complex functions as an autonomous disassembly machine with a preference for the export receptor Crm1. We describe three in vitro reconstituted disassembly intermediates, which show binding of a Crm1 export complex via two FG-repeat patches, cargo-release by RanBP2's Ran-binding domains and retention of free Crm1 at RanBP2 after Ran-GTP hydrolysis. Intriguingly, all intermediates are compatible with SUMO E3 ligase activity, suggesting that the RanBP2/RanGAP1*SUMO1/Ubc9 complex may link Crm1- and SUMO-dependent functions.
The contribution of lexical access speed to RAN and reading
DEFF Research Database (Denmark)
Poulsen, Mads
Purpose: The study investigated why and when rapid automatised naming is a predictor of reading. Specifically, we tested the hypotheses that (1) RAN-objects predicts reading because it is a measure of lexical (e.g. phonological) access speed, but (2) that RAN only becomes a predictor of reading...... development once a certain level of phonological recoding proficiency has been reached. Method: Forty Danish students without reading difficulties were administered tests of reading speed and accuracy, phoneme awareness, RAN-objects, timed confrontation picture naming, and visio-motor reaction time....... The students were sampled from two age groups representing two levels of recoding proficiency: Beginning readers in Grade 2-3 and proficient decoders in grade 5-6. We conducted hierarchical regression analyses on reading speed and accuracy to determine whether the relationship between RAN and reading...
5th Symposium on Hybrid RANS-LES Methods
Haase, Werner; Peng, Shia-Hui; Schwamborn, Dieter
2015-01-01
This book gathers the proceedings of the Fifth Symposium on Hybrid RANS-LES Methods, which was held on March 19-21 in College Station, Texas, USA. The different chapters, written by leading experts, reports on the most recent developments in flow physics modelling, and gives a special emphasis to industrially relevant applications of hybrid RANS-LES methods and other turbulence-resolving modelling approaches. The book addresses academic researchers, graduate students, industrial engineers, as well as industrial R&D managers and consultants dealing with turbulence modelling, simulation and measurement, and with multidisciplinary applications of computational fluid dynamics (CFD), such as flow control, aero-acoustics, aero-elasticity and CFD-based multidisciplinary optimization. It discusses in particular advanced hybrid RANS-LES methods. Further topics include wall-modelled Large Eddy Simulation (WMLES) methods, embedded LES, and a comparison of the LES methods with both hybrid RANS-LES and URANS methods. ...
RanBPM, a scaffolding protein for gametogenesis.
Puverel, Sandrine; Tessarollo, Lino
2013-01-01
RanBPM is a multimodular scaffold protein that interacts with a great variety of molecules including nuclear, cytoplasmic, and membrane proteins. By building multiprotein complexes, RanBPM is thought to regulate various signaling pathways, especially in the immune and nervous system. However, the diversity of these interactions does not facilitate the identification of its precise mechanism of action, and therefore the physiological role of RanBPM still remains unclear. Recently, RanBPM has been shown to be critical for the fertility of both genders in mouse. Although mechanistically it is still unclear how RanBPM affects gametogenesis, the data collected so far suggest that it is a key player in this process. Here, we examine the RanBPM sterility phenotype in the context of other genetic mutations affecting mouse gametogenesis to investigate whether this scaffold protein affects the function of other known proteins whose deficiency results in similar sterility phenotypes. Copyright © 2013 Elsevier Inc. All rights reserved.
Reynolds stress and shear flow generation
DEFF Research Database (Denmark)
Korsholm, Søren Bang; Michelsen, Poul; Naulin, V.
2001-01-01
to the treatment of the pseudo-Reynolds stress, we present analytical and numerical results which demonstrate that the Reynolds stress in a plasma, indeed, generates a poloidal shear flow. The numerical simulations are performed both in a drift wave turbulence regime and a resistive interchange turbulence regime......The so-called Reynolds stress may give a measure of the self-consistent flow generation in turbulent fluids and plasmas by the small-scale turbulent fluctuations. A measurement of the Reynolds stress can thus help to predict flows, e.g. shear flows in plasmas. This may assist the understanding...... of improved confinement scenarios such as H-mode confinement regimes. However, the determination of the Reynolds stress requires measurements of the plasma potential, a task that is difficult in general and nearly impossible in hot plasmas in large devices. In this work we investigate an alternative method...
Quantifying inflow uncertainties in RANS simulations of urban pollutant dispersion
García-Sánchez, C.; Van Tendeloo, G.; Gorlé, C.
2017-07-01
Numerical simulations of flow and pollutant dispersion in urban environments have the potential to support design and policy decisions that could reduce the population's exposure to air pollution. Reynolds-averaged Navier-Stokes simulations are a common modeling technique for urban flow and dispersion, but several sources of uncertainty in the simulations can affect the accuracy of the results. The present study proposes a method to quantify the uncertainty related to variability in the inflow boundary conditions. The method is applied to predict flow and pollutant dispersion in downtown Oklahoma City and the results are compared to field measurements available from the Joint Urban 2003 measurement campaign. Three uncertain parameters that define the inflow profiles for velocity, turbulence kinetic energy and turbulence dissipation are defined: the velocity magnitude and direction, and the terrain roughness length. The uncertain parameter space is defined based on the available measurement data, and a non-intrusive propagation approach that employs 729 simulations is used to quantify the uncertainty in the simulation output. A variance based sensitivity analysis is performed to identify the most influential uncertain parameters, and it is shown that the predicted tracer concentrations are influenced by all three uncertain variables. Subsequently, we specify different probability distributions for the uncertain inflow variables based on the available measurement data and calculate the corresponding means and 95% confidence intervals for comparison with the field measurements at 35 locations in downtown Oklahoma City.
RANS Modeling of Benchmark Shockwave / Boundary Layer Interaction Experiments
Georgiadis, Nick; Vyas, Manan; Yoder, Dennis
2010-01-01
This presentation summarizes the computations of a set of shock wave / turbulent boundary layer interaction (SWTBLI) test cases using the Wind-US code, as part of the 2010 American Institute of Aeronautics and Astronautics (AIAA) shock / boundary layer interaction workshop. The experiments involve supersonic flows in wind tunnels with a shock generator that directs an oblique shock wave toward the boundary layer along one of the walls of the wind tunnel. The Wind-US calculations utilized structured grid computations performed in Reynolds-averaged Navier-Stokes mode. Three turbulence models were investigated: the Spalart-Allmaras one-equation model, the Menter Shear Stress Transport wavenumber-angular frequency two-equation model, and an explicit algebraic stress wavenumber-angular frequency formulation. Effects of grid resolution and upwinding scheme were also considered. The results from the CFD calculations are compared to particle image velocimetry (PIV) data from the experiments. As expected, turbulence model effects dominated the accuracy of the solutions with upwinding scheme selection indicating minimal effects.!
DEFF Research Database (Denmark)
Skovgaard, M.; Nielsen, Peter V.
In this paper it is investigated if it is possible to simulate and capture some of the low Reynolds number effects numerically using time averaged momentum equations and a low Reynolds number k-f model. The test case is the larninar to turbulent transitional flow over a backward facing step...
Accurate load prediction by BEM with airfoil data from 3D RANS simulations
Schneider, Marc S.; Nitzsche, Jens; Hennings, Holger
2016-09-01
In this paper, two methods for the extraction of airfoil coefficients from 3D CFD simulations of a wind turbine rotor are investigated, and these coefficients are used to improve the load prediction of a BEM code. The coefficients are extracted from a number of steady RANS simulations, using either averaging of velocities in annular sections, or an inverse BEM approach for determination of the induction factors in the rotor plane. It is shown that these 3D rotor polars are able to capture the rotational augmentation at the inner part of the blade as well as the load reduction by 3D effects close to the blade tip. They are used as input to a simple BEM code and the results of this BEM with 3D rotor polars are compared to the predictions of BEM with 2D airfoil coefficients plus common empirical corrections for stall delay and tip loss. While BEM with 2D airfoil coefficients produces a very different radial distribution of loads than the RANS simulation, the BEM with 3D rotor polars manages to reproduce the loads from RANS very accurately for a variety of load cases, as long as the blade pitch angle is not too different from the cases from which the polars were extracted.
Reynolds Stresses and Hemolysis in Turbulent Flow Examined by Threshold Analysis
Directory of Open Access Journals (Sweden)
Mesude Ozturk
2016-12-01
Full Text Available Use of laminar flow-derived power law models to predict hemolysis with turbulence remains problematical. Flows in a Couette viscometer and a capillary tube have been simulated to investigate various combinations of Reynolds and/or viscous stresses power law models for hemolysis prediction. A finite volume-based computational method provided Reynolds and viscous stresses so that the effects of area-averaged and time-averaged Reynolds stresses, as well as total, viscous, and wall shear on hemolysis prediction could be assessed. The flow computations were conducted by using Reynolds-Averaged Navier-Stokes models of turbulence (k-ε and k-ω SST to simulate four different experimental conditions in a capillary tube and seven experimental conditions in a Couette viscometer taken from the literature. Power law models were compared by calculating standard errors between measured hemolysis values and those derived from power law models with data from the simulations. In addition, suitability of Reynolds and viscous stresses was studied by threshold analysis. Results showed there was no evidence of a threshold value for hemolysis in terms of Reynolds and viscous stresses. Therefore, Reynolds and viscous stresses are not good predictors of hemolysis. Of power law models, the Zhang power law model (Artificial Organs, 2011, 35, 1180–1186 gives the lowest error overall for the hemolysis index and Reynolds stress (0.05570, while Giersiepen’s model (The International journal of Artificial Organs, 1990, 13, 300–306 yields the highest (6.6658, and intermediate errors are found through use of Heuser’s (Biorheology, 1980, 17, 17–24 model (0.3861 and Fraser’s (Journal of Biomechanical Engineering, 2012, 134, 081002 model (0.3947.
Investigation on hydrodynamic performance of a marine propeller in oblique flow by RANS computations
Directory of Open Access Journals (Sweden)
Jianxi Yao
2015-01-01
Full Text Available This paper presents a numerical study on investigating on hydrodynamic characteristics of a marine propeller in oblique flow. The study is achieved by RANS simulations on an open source platform - OpenFOAM. A sliding grid approach is applied to compute the rotating motion of the propeller. Total force and moment acting on blades, as well as average force distributions in one revolution on propeller disk, are obtained for 70 cases of com- binations of advance ratios and oblique angles. The computed results are compared with available experimental data and discussed.
Haase, Werner; Peng, Shia-Hui; Schwamborn, Dieter
2013-01-01
The present book contains contributions presented at the Fourth Symposium on Hybrid RANS-LES Methods, held in Beijing, China, 28-30 September 2011, being a continuation of symposia taking place in Stockholm (Sweden, 2005), in Corfu (Greece, 2007), and Gdansk (Poland, 2009). The contributions to the last two symposia were published as NNFM, Vol. 97 and Vol. 111. At the Beijing symposium, along with seven invited keynotes, another 46 papers (plus 5 posters) were presented addressing topics on Novel turbulence-resolving simulation and modelling, Improved hybrid RANS-LES methods, Comparative studies of difference modelling methods, Modelling-related numerical issues and Industrial applications.. The present book reflects recent activities and new progress made in the development and applications of hybrid RANS-LES methods in general.
Marion Reynolds honored with emeritus status
Owczarski, Mark
2010-01-01
Marion Reynolds, professor of statistics in the College of Science and professor of forestry in the College of Natural Resources and Environment at Virginia Tech, has been conferred the "professor emeritus" title by the Virginia Tech Board of Visitors.
Understanding of Low Reynolds Number Aerodynamics and Micro Rotary-Wing Air Vehicles
Winslow, Justin Michael
The goal of the present research is to understand aerodynamics at low Reynolds numbers and synthesize rules towards the development of hovering micro rotary-wing air vehicles (MRAVs). This entailed the rigorous study of airfoil characteristics at low Reynolds numbers through available experimental results as well as the use of an unsteady Reynolds-Averaged Navier-Stokes solver. A systematic, experimental, variation of parameters approach with physical rotors was carried out to design and develop a micro air vehicle-scale rotor which maximizes the hover Figure of Merit. The insights gained in low Reynolds number aerodynamics have been utilized in the systematic design of a high endurance micro-quadrotor. Based on available characteristics, the physical relations governing electric propulsion system and structural weights have been derived towards a sizing methodology for small-scale rotary-wing vehicles.
Cloud RAN for Mobile Networks - a Technology Overview
DEFF Research Database (Denmark)
Checko, Aleksandra; Christiansen, Henrik Lehrmann; Yan, Ying
2014-01-01
Pool for statistical multiplexing gain, while shifting the burden to the high-speed wireline transmission of In-phase and Quadrature (IQ) data. C-RAN enables energy efficient network operation and possible cost savings on base- band resources. Furthermore, it improves network capacity by performing...
Envisioning Spectrum Management in Virtualised C-RAN
DEFF Research Database (Denmark)
Al-Samman, Imad; Artuso, Matteo; Christiansen, Henrik Lehrmann
2017-01-01
Cloud Radio Access Network (C-RAN) has attracted a worldwide attention in both academia and industry. This network architecture re-forming has been considered as a potential solution to meet the increasing capacity demands for future mobile data traffic. In addition, Network Virtualisation is a p...
Hybrid RANS-LES using high order numerical methods
Henry de Frahan, Marc; Yellapantula, Shashank; Vijayakumar, Ganesh; Knaus, Robert; Sprague, Michael
2017-11-01
Understanding the impact of wind turbine wake dynamics on downstream turbines is particularly important for the design of efficient wind farms. Due to their tractable computational cost, hybrid RANS/LES models are an attractive framework for simulating separation flows such as the wake dynamics behind a wind turbine. High-order numerical methods can be computationally efficient and provide increased accuracy in simulating complex flows. In the context of LES, high-order numerical methods have shown some success in predictions of turbulent flows. However, the specifics of hybrid RANS-LES models, including the transition region between both modeling frameworks, pose unique challenges for high-order numerical methods. In this work, we study the effect of increasing the order of accuracy of the numerical scheme in simulations of canonical turbulent flows using RANS, LES, and hybrid RANS-LES models. We describe the interactions between filtering, model transition, and order of accuracy and their effect on turbulence quantities such as kinetic energy spectra, boundary layer evolution, and dissipation rate. This work was funded by the U.S. Department of Energy, Exascale Computing Project, under Contract No. DE-AC36-08-GO28308 with the National Renewable Energy Laboratory.
Eye-Movement Control in RAN and Reading
Kuperman, Victor; Van Dyke, Julie A.; Henry, Regina
2016-01-01
The present study examined the "visual scanning hypothesis", which suggests that fluent oculomotor control is an important component underlying the predictive relationship between Rapid Automatized Naming (RAN) tasks and reading ability. Our approach was to isolate components of saccadic planning, articulation, and lexical retrieval in 3…
Simulating wind and marine hydrokinetic turbines with actuator lines in RANS and LES
Bachant, Peter; Wosnik, Martin
2015-11-01
As wind and marine hydrokinetic (MHK) turbine designs mature, focus is shifting towards improving turbine array layouts for maximizing overall power output, i.e., minimizing wake interference for axial-flow or horizontal-axis turbines, or taking advantage of constructive wake interaction for cross-flow or vertical-axis turbines. Towards this goal, an actuator line model (ALM) was developed to provide a computationally feasible method for simulating full turbine arrays inside Navier-Stokes models. The ALM predicts turbine loading with the blade element method combined with sub-models for dynamic stall and flow curvature. The open-source software is written as an extension library for the OpenFOAM CFD package, which allows the ALM body force to be applied to their standard RANS and LES solvers. Turbine forcing is also applied to volume of fluid (VOF) models, e.g., for predicting free surface effects on submerged MHK devices. An additional sub-model is considered for injecting turbulence model scalar quantities based on actuator line element loading. Results are presented for the simulation of performance and wake dynamics of axial- and cross-flow turbines and compared with moderate Reynolds number experiments and body-fitted mesh, blade-resolving CFD. Work supported by NSF-CBET grant 1150797.
Characterization of RanBPM Molecular Determinants that Control Its Subcellular Localization
Salemi, Louisa M.; Loureiro, Sandra O.; Schild-Poulter, Caroline
2015-01-01
RanBPM/RanBP9 is a ubiquitous, nucleocytoplasmic protein that is part of an evolutionary conserved E3 ubiquitin ligase complex whose function and targets in mammals are still unknown. RanBPM itself has been implicated in various cellular processes that involve both nuclear and cytoplasmic functions. However, to date, little is known about how RanBPM subcellular localization is regulated. We have conducted a systematic analysis of RanBPM regions that control its subcellular localization using RanBPM shRNA cells to examine ectopic RanBPM mutant subcellular localization without interference from the endogenously expressed protein. We show that several domains and motifs regulate RanBPM nuclear and cytoplasmic localization. In particular, RanBPM comprises two motifs that can confer nuclear localization, one proline/glutamine-rich motif in the extreme N-terminus which has a dominant effect on RanBPM localization, and a second motif in the C-terminus which minimally contributes to RanBPM nuclear targeting. We also identified a nuclear export signal (NES) which mutation prevented RanBPM accumulation in the cytoplasm. Likewise, deletion of the central RanBPM conserved domains (SPRY and LisH/CTLH) resulted in the relocalization of RanBPM to the nucleus, suggesting that RanBPM cytoplasmic localization is also conferred by protein-protein interactions that promote its cytoplasmic retention. Indeed we found that in the cytoplasm, RanBPM partially colocalizes with microtubules and associates with α-tubulin. Finally, in the nucleus, a significant fraction of RanBPM is associated with chromatin. Altogether, these analyses reveal that RanBPM subcellular localization results from the combined effects of several elements that either confer direct transport through the nucleocytoplasmic transport machinery or regulate it indirectly, likely through interactions with other proteins and by intramolecular folding. PMID:25659156
Smirnov, E. M.; Smirnovsky, A. A.; Schur, N. A.; Zaitsev, D. K.; Smirnov, P. E.
2017-10-01
Numerical simulations were carried out under conditions of the benchmark-quality experiments of Vogel&Eaton (1985), where nominally 2D fluid dynamics and heat transfer past a backward-facing step in a channel with expansion ratio of 1.25 was investigated at the Reynolds number of 28,000 (based on the step height and the upstream centreline velocity). Comparative computations were performed using an in-house finite-volume code SINF/Flag-S and the ANSYS Fluent, running the codes with same grids. Two approaches were used for turbulence modelling. First, the Menter SST turbulence model was used to perform refined 2D and 3D RANS steady-state computations. The 3D analysis was undertaken to evaluate influence of boundary layers developing on the sidewalls of the experimental channel. The data obtained has resulted in the conclusion that the side wall effects disturbing spanwise uniformity of wall friction and heated wall temperature in the test configuration were of the same order or less than the skin friction coefficient and the Stanton number measurement errors. Then, 3D time-dependent computations were carried out using the vortex-resolving IDDES method being a hybridization of RANS and LES. The IDDES results obtained with the two codes are in a satisfactory agreement, especially for the finer grid of 17.3 million cells. Comparing with the experimental data, the IDDES approach produces the best agreement for the wall friction, whereas the RANS solutions show superiority in predictions of the local Stanton number distribution.
Heat transfer at a stagnation point of impinging round air jet at low Reynolds numbers
Directory of Open Access Journals (Sweden)
Lemanov Vadim
2017-01-01
Full Text Available This work presents experimental investigation of average and pulsation thermal characteristics at the stagnation point of a round impinging air jet at low Reynolds numbers. In the experiments, the average and pulsation values of heat flux, heat transfer coefficient and Nusselt number were measured. At low Reynolds numbers (Re<4000, in contrast to the known monotonous increase in heat transfer, a non-monotonic change in heat transfer is shown. With an outflow from the tube, a significant increase in Nusselt number is observed in comparison with the case, when the jet flows from a nozzle, and this increase can be 300-500%.
Room Airflows with Low Reynolds Number Effects
DEFF Research Database (Denmark)
Topp, Claus; Nielsen, Peter V.; Davidson, Lars
is limited. It has been the objective to investigate the behaviour of a plane isothermal wall jet in a full-scale ventilated room at low Reynolds numbers, i.e. when the flow is not fully turbulent. The results are significantly different from known theory for fully turbulent flows. It was found that the jet......The behaviour of room airflows under fully turbulent conditions is well known both in terms of experiments and, numerical calculations by computational fluid dynamics (CFD). For room airflows where turbulence is not fully developed though, i.e. flows at low Reynolds numbers, the existing knowledge...... constants are a strong function of the Reynolds number up to a level of Reh≈500....
Effects of Low Reynolds Number on Wake-Generated Unsteady Flow of an Axial-Flow Turbine Rotor
Directory of Open Access Journals (Sweden)
Matsunuma Takayuki
2005-01-01
Full Text Available The unsteady flow field downstream of axial-flow turbine rotors at low Reynolds numbers was investigated experimentally using hot-wire probes. Reynolds number, based on rotor exit velocity and rotor chord length Re out,RT , was varied from 3.2× 10 4 to 12.8× 10 4 at intervals of 1.0× 10 4 by changing the flow velocity of the wind tunnel. The time-averaged and time-dependent distributions of velocity and turbulence intensity were analyzed to determine the effect of Reynolds number. The reduction of Reynolds number had a marked influence on the turbine flow field. The regions of high turbulence intensity due to the wake and the secondary vortices were increased dramatically with the decreasing Reynolds number. The periodic fluctuation of the flow due to rotor-stator interaction also increased with the decreasing Reynolds number. The energy-dissipation thickness of the rotor midspan wake at the low Reynolds number Re out,RT =3.2× 10 4 was 1.5 times larger than that at the high Reynolds number Re out,RT =12.8× 10 4 . The curve of the −0.2 power of the Reynolds number agreed with the measured energy-dissipation thickness at higher Reynolds numbers. However, the curve of the −0.4 power law fitted more closely than the curve of the −0.2 power law at lower Reynolds numbers below 6.4× 10 4 .
Tuisland. Karin Brynard. Kaapstad: Penguin Ran- dom House Suid ...
African Journals Online (AJOL)
Karin Brynard. Kaapstad: Penguin Ran- dom House Suid-Afrika, 2016. 576 pp. ISBN 978-1-4152-0693-5,. ISBN 978-1-4152-0668-3,. ISBN 978-1-4125-0669-0. DOI: http://dx.doi.org/10.17159/tvl.v.54i1.29. Tuisland (2016) is oud-joernalis Karin. Brynard se derde spanningsroman. Haar debuut, Plaasmoord (2009), is met die.
Directory of Open Access Journals (Sweden)
Azamat Aslanukov
2006-10-01
Full Text Available The Ran-binding protein 2 (RanBP2 is a large multimodular and pleiotropic protein. Several molecular partners with distinct functions interacting specifically with selective modules of RanBP2 have been identified. Yet, the significance of these interactions with RanBP2 and the genetic and physiological role(s of RanBP2 in a whole-animal model remain elusive. Here, we report the identification of two novel partners of RanBP2 and a novel physiological role of RanBP2 in a mouse model. RanBP2 associates in vitro and in vivo and colocalizes with the mitochondrial metallochaperone, Cox11, and the pacemaker of glycolysis, hexokinase type I (HKI via its leucine-rich domain. The leucine-rich domain of RanBP2 also exhibits strong chaperone activity toward intermediate and mature folding species of Cox11 supporting a chaperone role of RanBP2 in the cytosol during Cox11 biogenesis. Cox11 partially colocalizes with HKI, thus supporting additional and distinct roles in cell function. Cox11 is a strong inhibitor of HKI, and RanBP2 suppresses the inhibitory activity of Cox11 over HKI. To probe the physiological role of RanBP2 and its role in HKI function, a mouse model harboring a genetically disrupted RanBP2 locus was generated. RanBP2(-/- are embryonically lethal, and haploinsufficiency of RanBP2 in an inbred strain causes a pronounced decrease of HKI and ATP levels selectively in the central nervous system. Inbred RanBP2(+/- mice also exhibit deficits in growth rates and glucose catabolism without impairment of glucose uptake and gluconeogenesis. These phenotypes are accompanied by a decrease in the electrophysiological responses of photosensory and postreceptoral neurons. Hence, RanBP2 and its partners emerge as critical modulators of neuronal HKI, glucose catabolism, energy homeostasis, and targets for metabolic, aging disorders and allied neuropathies.
Turbulent pipe flow at extreme Reynolds numbers.
Hultmark, M; Vallikivi, M; Bailey, S C C; Smits, A J
2012-03-02
Both the inherent intractability and complex beauty of turbulence reside in its large range of physical and temporal scales. This range of scales is captured by the Reynolds number, which in nature and in many engineering applications can be as large as 10(5)-10(6). Here, we report turbulence measurements over an unprecedented range of Reynolds numbers using a unique combination of a high-pressure air facility and a new nanoscale anemometry probe. The results reveal previously unknown universal scaling behavior for the turbulent velocity fluctuations, which is remarkably similar to the well-known scaling behavior of the mean velocity distribution.
Applicability of RANS, DES and LES in propeller flow noise
Directory of Open Access Journals (Sweden)
LU Li
2017-12-01
Full Text Available [Objectives] In order to study the applicability of different turbulence models in propeller flow noise prediction, taking the DTMB 4119 propeller as the research object, the numerical simulation method is used to calculate the frequency domain noise under the non-uniform flow field.[Methods] First, the hydrodynamic coefficient and surface pressure distribution coefficient are obtained via the RANS method and the accuracy of the flow field simulation is verified by comparing it with the experimental data. Next,the pulsating pressures obtained by RANS, DES and LES are considered as the sound source respectively, and combined with the acoustic boundary element method to predict the radiation noise.[Results] The results show that spectral noise is the main contributor to total noise; when noise on 1 BPF is predicted, the results obtained by the three methods are very similar, so we can use RANS to predict noise quickly; when noise on the high order of BPF needs to be predicted, the calculation results of LES are better.[Conclusions] In noise prediction, the appropriate turbulence simulation method can be selected according to the demand.
AVHRR GAC SST Reanalysis Version 1 (RAN1
Directory of Open Access Journals (Sweden)
Alexander Ignatov
2016-04-01
Full Text Available In response to its users’ needs, the National Oceanic and Atmospheric Administration (NOAA initiated reanalysis (RAN of the Advanced Very High Resolution Radiometer (AVHRR Global Area Coverage (GAC; 4 km sea surface temperature (SST data employing its Advanced Clear Sky Processor for Oceans (ACSPO retrieval system. Initially, AVHRR/3 data from five NOAA and two Metop satellites from 2002 to 2015 have been reprocessed. The derived SSTs have been matched up with two reference SSTs—the quality controlled in situ SSTs from the NOAA in situ Quality Monitor (iQuam and the Canadian Meteorological Centre (CMC L4 SST analysis—and analyzed in the NOAA SST Quality Monitor (SQUAM online system. The corresponding clear-sky ocean brightness temperatures (BT in AVHRR bands 3b, 4 and 5 (centered at 3.7, 11, and 12 µm, respectively have been compared with the Community Radiative Transfer Model simulations in another NOAA online system, Monitoring of Infrared Clear-sky Radiances over Ocean for SST (MICROS. For some AVHRRs, the time series of “AVHRR minus reference” SSTs and “observed minus model” BTs are unstable and inconsistent, with artifacts in the SSTs and BTs strongly correlated. In the official “Reanalysis version 1” (RAN1, data from only five platforms—two midmorning (NOAA-17 and Metop-A and three afternoon (NOAA-16, -18 and -19—were included during the most stable periods of their operations. The stability of the SST time series was further improved using variable regression SST coefficients, similarly to how it was done in the NOAA/NASA Pathfinder version 5.2 (PFV5.2 dataset. For data assimilation applications, especially those blending satellite and in situ SSTs, we recommend bias-correcting the RAN1 SSTs using the newly developed sensor-specific error statistics (SSES, which are reported in the product files. Relative performance of RAN1 and PFV5.2 SSTs is discussed. Work is underway to improve the calibration of AVHRR/3s and
Sinha, Vimlendu Bhushan; Grover, Atul; Singh, Sadhana; Pande, Veena; Ahmed, Zakwan
2014-09-01
Ran is a multifunctional small GTPase involved in important cellular activities like nucleocytoplasmic transport, mitotic spindle assembly, nuclear envelope formation, etc., but is also known to be differentially expressed in response to abiotic stress, particularly low temperature. We have over-expressed Lepidium latifolium (Fam. Brassicaceae) Ran gene in tobacco to study the response of the plants to cold stress (24 h; 4 °C). Transformation of the tobacco plants was verified using PCR targeting Ran gene and co-transformed selectable marker gene nptII. Segregation in Mendelian ratios was validated in five transgenic lines by germination of T1 and T2 seeds on moist filter papers containing 150 mg/l kanamycin. Higher levels of electrolyte leakage and lipid peroxidation pointed towards hypersensitivity of plants. Similarly, lesser proline accumulation compared to wild types also indicated susceptibility of plants to death under chilling conditions. Specific activity of antioxidant enzymes superoxide dismutase and glutathione reductase was also measured under stressed and control conditions. A variation was observed across the different lines, and four out of five lines showed lesser specific activity compared to wild type plants, thus indicating reduced capability of scavenging free radicals. In totality, a strong evidence on induced hypersensitivity to cold stress has been collected which may further be helpful in designing appropriate strategies for engineering crop plants for survival under cold stress conditions.
Boundary induced nonlinearities at small Reynolds numbers
Sbragaglia, M.; Sugiyama, K.
2007-01-01
We investigate the importance of boundary slip at finite Reynolds numbers for mixed boundary conditions. Nonlinear effects are induced by the non-homogeneity of the boundary condition and change the symmetry properties of the flow with an overall mean flow reduction. To explain the observed drag
Revised Reynolds Stress and Triple Product Models
Olsen, Michael E.; Lillard, Randolph P.
2017-01-01
Revised versions of Lag methodology Reynolds-stress and triple product models are applied to accepted test cases to assess the improvement, or lack thereof, in the prediction capability of the models. The Bachalo-Johnson bump flow is shown as an example for this abstract submission.
Kathryn Reynolds | IDRC - International Development Research ...
International Development Research Centre (IDRC) Digital Library (Canada)
Kathryn Reynolds is Regional Director, Middle East and North Africa, based in Cairo, Egypt. Previously, she was Senior Legal Counsel at IDRC. Before joining IDRC in 2012, Kathryn worked in the legal and policy divisions of federal government and not-for-profit institutions. She holds an LL.B. from the University of Ottawa, ...
Optimal Swimming at low Reynolds numbers
Avron, J. E.; Gat, O.; Kenneth, O.
2004-01-01
Efficient swimming at low Reynolds numbers is a major concern of microbots. To compare the efficiencies of different swimmers we introduce the notion of ``swimming drag coefficient'' which allows for the ranking of swimmers. We find the optimal swimmer within a certain class of two dimensional swimmers using conformal mappings techniques.
Boruc, Joanna; Griffis, Anna H N; Rodrigo-Peiris, Thushani; Zhou, Xiao; Tilford, Bailey; Van Damme, Daniël; Meier, Iris
2015-07-01
The Ran GTPase activating protein (RanGAP) is important to Ran signaling involved in nucleocytoplasmic transport, spindle organization, and postmitotic nuclear assembly. Unlike vertebrate and yeast RanGAP, plant RanGAP has an N-terminal WPP domain, required for nuclear envelope association and several mitotic locations of Arabidopsis thaliana RanGAP1. A double null mutant of the two Arabidopsis RanGAP homologs is gametophyte lethal. Here, we created a series of mutants with various reductions in RanGAP levels by combining a RanGAP1 null allele with different RanGAP2 alleles. As RanGAP level decreases, the severity of developmental phenotypes increases, but nuclear import is unaffected. To dissect whether the GAP activity and/or the subcellular localization of RanGAP are responsible for the observed phenotypes, this series of rangap mutants were transformed with RanGAP1 variants carrying point mutations abolishing the GAP activity and/or the WPP-dependent subcellular localization. The data show that plant development is differentially affected by RanGAP mutant allele combinations of increasing severity and requires the GAP activity of RanGAP, while the subcellular positioning of RanGAP is dispensable. In addition, our results indicate that nucleocytoplasmic trafficking can tolerate both partial depletion of RanGAP and delocalization of RanGAP from the nuclear envelope. © 2015 American Society of Plant Biologists. All rights reserved.
Hybrid RANS/LES applied to complex terrain
DEFF Research Database (Denmark)
Bechmann, Andreas; Sørensen, Niels N.
2011-01-01
Large Eddy Simulation (LES) of the wind in complex terrain is limited by computational cost. The number of computational grid points required to resolve the near-ground turbulent structures (eddies) are very high. The traditional solution to the problem has been to apply a wall function...... aspect ratio in the RANS layer and thereby resolve the mean near-wall velocity profile. The method is applicable to complex terrain and the benefits of traditional LES are kept intact. Using the hybrid method, simulations of the wind over a natural complex terrain near Wellington in New Zealand...
Revolutionary Performance For Ultra Low Reynolds Number Vehicles Project
National Aeronautics and Space Administration — A novel technique for controlling transition from laminar to turbulent flow in very low Reynolds number conditions has been developed. Normally flows with Reynolds...
Numerical Study Comparing RANS and LES Approaches on a Circulation Control Airfoil
Rumsey, Christopher L.; Nishino, Takafumi
2011-01-01
A numerical study over a nominally two-dimensional circulation control airfoil is performed using a large-eddy simulation code and two Reynolds-averaged Navier-Stokes codes. Different Coanda jet blowing conditions are investigated. In addition to investigating the influence of grid density, a comparison is made between incompressible and compressible flow solvers. The incompressible equations are found to yield negligible differences from the compressible equations up to at least a jet exit Mach number of 0.64. The effects of different turbulence models are also studied. Models that do not account for streamline curvature effects tend to predict jet separation from the Coanda surface too late, and can produce non-physical solutions at high blowing rates. Three different turbulence models that account for streamline curvature are compared with each other and with large eddy simulation solutions. All three models are found to predict the Coanda jet separation location reasonably well, but one of the models predicts specific flow field details near the Coanda surface prior to separation much better than the other two. All Reynolds-averaged Navier-Stokes computations produce higher circulation than large eddy simulation computations, with different stagnation point location and greater flow acceleration around the nose onto the upper surface. The precise reasons for the higher circulation are not clear, although it is not solely a function of predicting the jet separation location correctly.
78 FR 56610 - Drawbridge Operation Regulations; Reynolds Channel, Lawrence, NY
2013-09-13
... SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; Reynolds Channel, Lawrence, NY... operation of the Atlantic Beach Bridge, mile 0.4, across Reynolds Channel, at Lawrence, New York. This... Atlantic Beach Bridge, across Reynolds Channel, mile 0.4, at Lawrence, New York, has a vertical clearance...
78 FR 66265 - Drawbridge Operation Regulations; Reynolds Channel, Lawrence, NY
2013-11-05
... SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; Reynolds Channel, Lawrence, NY... operation of the Atlantic Beach Bridge, mile 0.4, across Reynolds Channel, at Lawrence, New York. This... Atlantic Beach Bridge, across Reynolds Channel, mile 0.4, at Lawrence, New York, has a vertical clearance...
77 FR 37316 - Drawbridge Operation Regulations; Reynolds Channel, Nassau, NY
2012-06-21
... SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; Reynolds Channel, Nassau, NY AGENCY... the Long Beach Bridge, mile 4.7, across Reynolds Channel, at Nassau, New York. This temporary... Operations, telephone 202-366-9826. SUPPLEMENTARY INFORMATION: The Long Beach Bridge, across Reynolds Channel...
78 FR 34893 - Drawbridge Operation Regulations; Reynolds Channel, Lawrence, NY
2013-06-11
... SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; Reynolds Channel, Lawrence, NY... operation of the Atlantic Beach Bridge, mile 0.4, across Reynolds Channel, at Lawrence, New York. This...-9826. SUPPLEMENTARY INFORMATION: The Atlantic Beach Bridge, across Reynolds Channel, mile 0.4, at...
Characterizing overwater roughness Reynolds number during hurricanes
Hsu, S. A.; Shen, Hui; He, Yijun
2017-11-01
The Reynolds number, which is the dimensionless ratio of the inertial force to the viscous force, is of great importance in the theory of hydrodynamic stability and the origin of turbulence. To investigate aerodynamically rough flow over a wind sea, pertinent measurements of wind and wave parameters from three data buoys during Hurricanes Kate, Lili, Ivan, Katrina, Rita, and Wilma are analyzed. It is demonstrated that wind seas prevail when the wind speed at 10 m and the wave steepness exceed 9 m s-1 and 0.020, respectively. It is found that using a power law the roughness Reynolds number is statistically significantly related to the significant wave height instead of the wind speed as used in the literature. The reason for this characterization is to avoid any self-correlation between Reynolds number and the wind speed. It is found that although most values of R_{*} were below 500, they could reach to approximately 1000 near the radius of maximum wind. It is shown that, when the significant wave height exceeds approximately 2 m in a wind sea, the air flow over that wind sea is already under the fully rough condition. Further analysis of simultaneous measurements of wind and wave parameters using the logarithmic law indicates that the estimated overwater friction velocity is consistent with other methods including the direct (eddy-covariance flux) measurements, the atmospheric vorticity approach, and the sea-surface current measurements during four slow moving super typhoons with wind speed up to 70 m s-1.
Assessment of Cavitation Erosion with a Multiphase Reynolds-Averaged Navier-Stokes Method
Li, Z.R.
2012-01-01
Cavitation erosion is one of the remarkable catastrophic consequences of cavitation. Predicting the cavitation aggressiveness quantitatively and predicting the most probable location of cavitation erosion are complex problems that currently still motivate an important amount of basic and applied
Identification of severe wind conditions using a Reynolds averaged Navier-Stokes solver
DEFF Research Database (Denmark)
Sørensen, Niels N.; Bechmann, Andreas; Johansen, Jeppe
2007-01-01
The present paper describes the application of a Navier-Stokes solver to predict the presence of severe flow conditions in complex terrain, capturing conditions that may be critical to the siting of wind turbines in the terrain. First it is documented that the flow solver is capable of predicting...... the flow in the complex terrain by comparing with measurements from two meteorology masts. Next, it is illustrated how levels of turbulent kinetic energy can be used to easily identify areas with severe flow conditions, relying on a high correlation between high turbulence intensity and severe flow...
Identification of severe wind conditions using a Reynolds Averaged Navier-Stokes solver
Sørensen, N. N.; Bechmann, A.; Johansen, J.; Myllerup, L.; Botha, P.; Vinther, S.; Nielsen, B. S.
2007-07-01
The present paper describes the application of a Navier-Stokes solver to predict the presence of severe flow conditions in complex terrain, capturing conditions that may be critical to the siting of wind turbines in the terrain. First it is documented that the flow solver is capable of predicting the flow in the complex terrain by comparing with measurements from two meteorology masts. Next, it is illustrated how levels of turbulent kinetic energy can be used to easily identify areas with severe flow conditions, relying on a high correlation between high turbulence intensity and severe flow conditions, in the form of high wind shear and directional shear which may seriously lower the lifetime of a wind turbine.
Aggresome formation is regulated by RanBPM through an interaction with HDAC6
Directory of Open Access Journals (Sweden)
Louisa M. Salemi
2014-05-01
Full Text Available In conditions of proteasomal impairment, the build-up of damaged or misfolded proteins activates a cellular response leading to the recruitment of damaged proteins into perinuclear aggregates called aggresomes. Aggresome formation involves the retrograde transport of cargo proteins along the microtubule network and is dependent on the histone deacetylase HDAC6. Here we show that ionizing radiation (IR promotes Ran-Binding Protein M (RanBPM relocalization into discrete perinuclear foci where it co-localizes with aggresome components ubiquitin, dynein and HDAC6, suggesting that the RanBPM perinuclear clusters correspond to aggresomes. RanBPM was also recruited to aggresomes following treatment with the proteasome inhibitor MG132 and the DNA-damaging agent etoposide. Strikingly, aggresome formation by HDAC6 was markedly impaired in RanBPM shRNA cells, but was restored by re-expression of RanBPM. RanBPM was found to interact with HDAC6 and to inhibit its deacetylase activity. This interaction was abrogated by a RanBPM deletion of its LisH/CTLH domain, which also prevented aggresome formation, suggesting that RanBPM promotes aggresome formation through an association with HDAC6. Our results suggest that RanBPM regulates HDAC6 activity and is a central regulator of aggresome formation.
Stokesian swimming of a prolate spheroid at low Reynolds number
Felderhof, B U
2016-01-01
The swimming of a spheroid immersed in a viscous fluid and performing surface deformations periodically in time is studied on the basis of Stokes equations of low Reynolds number hydrodynamics. The average over a period of time of the swimming velocity and the rate of dissipation are given by integral expressions of second order in the amplitude of surface deformations. The first order flow velocity and pressure, as functions of spheroidal coordinates, are expressed as sums of basic solutions of Stokes equations. Sets of superposition coefficients of these solutions which optimize the mean swimming speed for given power are derived from an eigenvalue problem. The maximum eigenvalue is a measure of the efficiency of the optimal stroke within the chosen class of motions. The maximum eigenvalue for sets of low order is found to be a strongly increasing function of the aspect ratio of the spheroid.
Local vibrations and lift performance of low Reynolds number airfoil
Directory of Open Access Journals (Sweden)
TariqAmin Khan
2017-06-01
Full Text Available The 2D incompressible Navier-Stokes equations are solved based on the finite volume method and dynamic mesh technique is used to carry out partial fluid structure interaction. The local flexible structure (hereinafter termed as flexible structure vibrates in a single mode located on the upper surface of the airfoil. The Influence of vibration frequency and amplitude are examined and the corresponding fluid flow characteristics are investigated which add complexity to the inherent problem in unsteady flow. The study is conducted for flow over NACA0012 airfoil at 600≤Re≤3000 at a low angle of attack. Vibration of flexible structure induces a secondary vortex which modifies the pressure distribution and lift performance of the airfoil. At some moderate vibration amplitude, frequency synchronization or lock-in phenomenon occurs when the vibration frequency is close to the characteristic frequency of rigid airfoil. Evolution and shedding of vortices corresponding to the deformation of flexible structure depends on the Reynolds number. In the case of Re≤1000, the deformation of flexible structure is considered in-phase with the vortex shedding i.e., increasing maximum lift is linked with the positive deformation of flexible structure. At Re=1500 a phase shift of about 1/π exists while they are out-of-phase at Re>1500. Moreover, the oscillation amplitude of lift coefficient increases with increasing vibration amplitude for Re≤1500 while it decreases with increasing vibration amplitude for Re>1500. As a result of frequency lock-in, the average lift coefficient is increased with increasing vibration amplitude for all investigated Reynolds numbers (Re. The maximum increase in the average lift coefficient is 19.72% within the range of investigated parameters.
A Taylor-Microscale Transport Model for RANS
Israel, Daniel; Hsu, Abigail; Rudolph, Joshua
2017-11-01
Since the first development of complete two-equation RANS models, there have been a variety of proposals for the choice of a second scaling quantity. Some of the most popular have been a time-scale ω (Kolmogorov, 1942; Wilcox, 1998), the dissipation rate ɛ (Harlow et al., 1968), the integral length-scale L, and the product kl (Mellor et al., 1982). All of these are formally equivalent in the production and dissipation terms, and differ only in which quantity is turbulently diffused. They also all rely on an equilibrium assumption that links the dissipation rate at the small scales to the scale of the large eddies. We propose using the Taylor microscale as the second scale. This has several nice properties, and also exhibits some interesting mathematical differences from conventional models. We show results for some simple shear flows using the new model.
Computation of vortex-shedding flows past a square cylinder employing LES and RANS
Energy Technology Data Exchange (ETDEWEB)
Lakehal, D.; Thiele, F. [Technische Univ. Berlin (Germany). Hermann Foettinger Inst. fuer Stroemungsmechanik; Duchamp de Lageneste, L.; Buffat, M. [LMFA, Ecole Centrale de Lyon, Ecully (France)
1998-12-31
The paper addresses the predictive capabilities of different computational modelling practices which employ various eddy-viscosity models for turbulence, that are based on a linear, a quadratic and two cubic representations of the Reynolds stress tensor in terms of strain and vorticity rates respectively, in the context of a comparative study between Reynolds-Averaged Navier-Stokes Equations and Large Eddy Simulation of vortex-shedding flows. The test case considered here refers to the familiar vortex-shedding flow past a square cylinder at R{sub e}=22.000 studied experimentally by Lyn et al. All the models were found to reproduce fairly well the shedding dynamics with the exception of eddy-viscosity models employed with a high rate of oncoming turbulence. The total kinetic energy was fairly well predicted by all models, whereas the turbulent part was significantly underestimated. Comparison of this latter quantity has emphasized the effective role of turbulence anisotropy in rendering the effects of shedding mechanisms. The integral parameters were determined with much better agreement with measurements than the averaged quantities. The essential finding is that the explicit algebraic stress models predict much better the global parameters with increasing the order of anisotropy. The confusing results of Large Eddy Simulation, i.e. satisfactory agreements of the time-averaged velocity and energy profiles to the expense of a less accurate prediction of the global coefficients, did not support the superiority of the concept. Still, the practice has revealed a particular sentivity to the near-wall treatment. (orig.)
Papadopoulos, Timothy C.; Spanoudis, George C.; Georgiou, George K.
2016-01-01
We examined the prominent theoretical explanations of the RAN-reading relationship in a relatively transparent language (Greek) in a sample of children (n = 286) followed from Grade 1 to Grade 2. Specifically, we tested the fit of eight different models, as defined by the type of reading performance predicted (oral vs. silent word reading fluency), the type of RAN tasks (non-alphanumeric vs. alphanumeric), and the RAN effects (direct vs. indirect). Working memory, attention, processing speed, and motor skills were used as “common cause” variables predicting both RAN and reading fluency and phonological awareness and orthographic processing were used as mediators of RAN's effects on reading fluency. The findings of both concurrent and longitudinal analyses indicated that RAN is a unique predictor of oral reading fluency, but not silent reading fluency. Using alphanumeric or non-alphanumeric RAN did not particularly affect the RAN-reading relationship. Both phonological awareness and orthographic processing partly mediated RAN's effects on reading fluency. Theoretical implications of these findings are discussed. PMID:27605918
Energy Technology Data Exchange (ETDEWEB)
Bacot-Davis, Valjean R., E-mail: bacotdavis@wisc.edu [Institute for Molecular Virology, University of Wisconsin-Madison, R.M. Bock Laboratories, 1525 Linden Dr. Madison, WI 53706 (United States); Palmenberg, Ann C., E-mail: acpalmen@wisc.edu [Institute for Molecular Virology, University of Wisconsin-Madison, R.M. Bock Laboratories, 1525 Linden Dr. Madison, WI 53706 (United States); Department of Biochemistry, University of Wisconsin-Madison, R.M. Bock Laboratories, 1525 Linden Dr. Madison, WI 53706 (United States)
2013-08-15
Encephalomyocarditis virus (EMCV), a Cardiovirus, initiates its polyprotein with a short 67 amino acid Leader (L) sequence. The protein acts as a unique pathogenicity factor, with anti-host activities which include the triggering of nuclear pore complex hyperphosphorylation and direct binding inhibition of the active cellular transport protein, Ran GTPase. Chemical modifications and protein mutagenesis now map the Ran binding domain to the L hinge-linker region, and in particular, to amino acids 35–40. Large deletions affecting this region were shown previously to diminish Ran binding. New point mutations, especially K35Q, D37A and W40A, preserve the intact L structure, abolish Ran binding and are deficient for nucleoporin (Nup) hyperphosphorylation. Ran itself morphs through multiple configurations, but reacts most effectively with L when in the GDP format, preferably with an empty nucleotide binding pocket. Therefore, L:Ran binding, mediated by the linker-hinge, is a required step in L-induced nuclear transport inhibition. - Highlights: • The hinge domain provides critical residues in Cardiovirus L:Ran complex formation. • Leader prefers to bind Ran in a nucleotide free, GDP-conformation. • L-induced Nup62 phosphorylation is reduced with Ran-deficient binding mutations.
Papadopoulos, Timothy C; Spanoudis, George C; Georgiou, George K
2016-01-01
We examined the prominent theoretical explanations of the RAN-reading relationship in a relatively transparent language (Greek) in a sample of children (n = 286) followed from Grade 1 to Grade 2. Specifically, we tested the fit of eight different models, as defined by the type of reading performance predicted (oral vs. silent word reading fluency), the type of RAN tasks (non-alphanumeric vs. alphanumeric), and the RAN effects (direct vs. indirect). Working memory, attention, processing speed, and motor skills were used as "common cause" variables predicting both RAN and reading fluency and phonological awareness and orthographic processing were used as mediators of RAN's effects on reading fluency. The findings of both concurrent and longitudinal analyses indicated that RAN is a unique predictor of oral reading fluency, but not silent reading fluency. Using alphanumeric or non-alphanumeric RAN did not particularly affect the RAN-reading relationship. Both phonological awareness and orthographic processing partly mediated RAN's effects on reading fluency. Theoretical implications of these findings are discussed.
Flapping hydrofoil performance at low Reynolds numbers
Energy Technology Data Exchange (ETDEWEB)
Pedro, G.; Suleman, A.; Djilali, N. [Univ. of Victoria, Dept. of Mechanical Engineering, Victoria, British Columbia (Canada)]. E-mail: gpedro@uvic.ca; suleman@uvic.ca; ndjilali@uvic.ca
2003-07-01
This paper relates the study of unsteady flow past oscillating hydrofoils at low Reynolds numbers using a computational fluid dynamics research code based on structured grids. The solver utilizes an explicit, time-stepping algorithm with an Arbitrary Lagrangian-Eulerian formulation to account for mesh movement. The viscous flow past a NACA0012 hydrofoil at various pitching and heaving frequencies and other design parameters is simulated. The effect of these parameters on thrust, power and efficiency is studied along with flow field visualisations to account for these variations. (author)
Rigorous Error Estimates for Reynolds' Lubrication Approximation
Wilkening, Jon
2006-11-01
Reynolds' lubrication equation is used extensively in engineering calculations to study flows between moving machine parts, e.g. in journal bearings or computer disk drives. It is also used extensively in micro- and bio-fluid mechanics to model creeping flows through narrow channels and in thin films. To date, the only rigorous justification of this equation (due to Bayada and Chambat in 1986 and to Nazarov in 1987) states that the solution of the Navier-Stokes equations converges to the solution of Reynolds' equation in the limit as the aspect ratio ɛ approaches zero. In this talk, I will show how the constants in these error bounds depend on the geometry. More specifically, I will show how to compute expansion solutions of the Stokes equations in a 2-d periodic geometry to arbitrary order and exhibit error estimates with constants which are either (1) given in the problem statement or easily computable from h(x), or (2) difficult to compute but universal (independent of h(x)). Studying the constants in the latter category, we find that the effective radius of convergence actually increases through 10th order, but then begins to decrease as the inverse of the order, indicating that the expansion solution is probably an asymptotic series rather than a convergent series.
C114 Low Reynolds Number Airfoil Design Optimization
大山, 聖; 藤井, 孝藏; Akira, Oyama; Kozo, Fujii; JAXA ISAS; Division for Space Transportation Eng., JAXA ISAS
2004-01-01
Low Reynolds number airfoil design optimization is demonstrated. A two-dimensional Navier-Stokes solver is used for aerodynamic performance estimation of the airfoil design candidates because the viscosity effect is not negligible at low Reynolds number flight condition. An evolutionary computation is used for robust airfoil design optimization. The result demonstrated that the optimized airfoil is a very thin airfoil with significant camber. The result also showed that the low Reynolds numbe...
Wolff, Ulrika
2014-07-01
Although phonemic awareness is a well-known factor predicting early reading development, there is also evidence that Rapid Automatized Naming (RAN) is an independent factor that contributes to early reading. The aim of this study is to examine phonemic awareness and RAN as predictors of reading speed, reading comprehension and spelling for children with reading difficulties. It also investigates a possible reciprocal relationship between RAN and reading skills, and the possibility of enhancing RAN by intervention. These issues are addressed by examining longitudinal data from a randomised reading intervention study carried out in Sweden for 9-year-old children with reading difficulties (N = 112). The intervention comprised three main elements: training of phonics, reading comprehension strategies and reading speed. The analysis of the data was carried out using structural equation modelling. The results demonstrated that after controlling for autoregressive effects and non-verbal IQ, RAN predicts reading speed whereas phonemic awareness predicts reading comprehension and spelling. RAN was significantly enhanced by training and a reciprocal relationship between reading speed and RAN was found. These findings contribute to support the view that both phonemic awareness and RAN independently influence early phases of reading, and that both are possible to enhance by training.
RAN as a Predictor of Reading Skills, and Vice Versa: Results from a Randomised Reading Intervention
Wolff, Ulrika
2014-01-01
Although phonemic awareness is a well-known factor predicting early reading development, there is also evidence that Rapid Automatized Naming (RAN) is an independent factor that contributes to early reading. The aim of this study is to examine phonemic awareness and RAN as predictors of reading speed, reading comprehension and spelling for…
Mesh Resolution Effect on 3D RANS Turbomachinery Flow Simulations
Yershov, Sergiy
2016-01-01
The paper presents the study of the effect of a mesh refinement on numerical results of 3D RANS computations of turbomachinery flows. The CFD solver F, which based on the second-order accurate ENO scheme, is used in this study. The simplified multigrid algorithm and local time stepping permit decreasing computational time. The flow computations are performed for a number of turbine and compressor cascades and stages. In all flow cases, the successively refined meshes of H-type with an approximate orthogonalization near the solid walls were generated. The results obtained are compared in order to estimate their both mesh convergence and ability to resolve the transonic flow pattern. It is concluded that for thorough studying the fine phenomena of the 3D turbomachinery flows, it makes sense to use the computational meshes with the number of cells from several millions up to several hundred millions per a single turbomachinery blade channel, while for industrial computations, a mesh of about or less than one mil...
Dynamic Multiscale Averaging (DMA) of Turbulent Flow
Energy Technology Data Exchange (ETDEWEB)
Richard W. Johnson
2012-09-01
A new approach called dynamic multiscale averaging (DMA) for computing the effects of turbulent flow is described. The new method encompasses multiple applications of temporal and spatial averaging, that is, multiscale operations. Initially, a direct numerical simulation (DNS) is performed for a relatively short time; it is envisioned that this short time should be long enough to capture several fluctuating time periods of the smallest scales. The flow field variables are subject to running time averaging during the DNS. After the relatively short time, the time-averaged variables are volume averaged onto a coarser grid. Both time and volume averaging of the describing equations generate correlations in the averaged equations. These correlations are computed from the flow field and added as source terms to the computation on the next coarser mesh. They represent coupling between the two adjacent scales. Since they are computed directly from first principles, there is no modeling involved. However, there is approximation involved in the coupling correlations as the flow field has been computed for only a relatively short time. After the time and spatial averaging operations are applied at a given stage, new computations are performed on the next coarser mesh using a larger time step. The process continues until the coarsest scale needed is reached. New correlations are created for each averaging procedure. The number of averaging operations needed is expected to be problem dependent. The new DMA approach is applied to a relatively low Reynolds number flow in a square duct segment. Time-averaged stream-wise velocity and vorticity contours from the DMA approach appear to be very similar to a full DNS for a similar flow reported in the literature. Expected symmetry for the final results is produced for the DMA method. The results obtained indicate that DMA holds significant potential in being able to accurately compute turbulent flow without modeling for practical
78 FR 56609 - Drawbridge Operation Regulations; Reynolds Channel, Lawrence, NY
2013-09-13
... SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; Reynolds Channel, Lawrence, NY... 34893) governing the operation of the Atlantic Beach Bridge, mile 0.4, across Reynolds Channel, at... Channel, Lawrence, NY'', in the Federal Register (78 FR 34893). The temporary deviation concerned was for...
78 FR 37456 - Drawbridge Operation Regulations; Reynolds Channel, Nassau, NY
2013-06-21
... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; Reynolds Channel, Nassau, NY AGENCY... the Long Beach Bridge, mile 4.7, across Reynolds Channel at Nassau, New York. Under this temporary...
78 FR 26508 - Drawbridge Operation Regulations; Reynolds Channel, Nassau, NY
2013-05-07
... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 117 Drawbridge Operation Regulations; Reynolds Channel, Nassau, NY AGENCY... the Long Beach Bridge, mile 4.7, across Reynolds Channel at Nassau, New York. Under this temporary...
On Reynolds stress and neutral azimuthal modes in the stability ...
Indian Academy of Sciences (India)
Reynolds stress. 1. Introduction. The stability of swirling flows has been studied extensively and for the vast literature on this problem one may be referred to the .... Moreover, in the recent work of Maslowe & Nigam (2008) linear and ... which is different from that of parallel shear flows in which case the Reynolds stress is.
Directory of Open Access Journals (Sweden)
TIMOTHY C PAPADOPOULOS
2016-08-01
Full Text Available We examined the prominent theoretical explanations of the RAN-reading relationship in a relatively transparent language (Greek in a sample of children (n= 286 followed from Grade 1 to Grade 2. Specifically, we tested the fit of eight different models, as defined by the type of reading performance predicted (oral vs. silent word reading fluency, the type of RAN tasks (non-alphanumeric vs. alphanumeric, and the RAN effects (direct vs. indirect. Working memory, attention, processing speed, and motor skills were used as common cause variables predicting both RAN and reading fluency and phonological awareness and orthographic processing were used as mediators of RAN’s effects on reading fluency. The findings of both concurrent and longitudinal analyses indicated that RAN is a unique predictor of oral reading fluency, but not silent reading fluency. Using alphanumeric or non-alphanumeric RAN did not particularly affect the RAN-reading relationship. Both phonological awareness and orthographic processing partly mediated RAN’s effects on reading fluency. Theoretical implications of these findings are discussed.
RANS Simulations of Aerodynamic Performance of NACA 0015 Flapped Airfoil
Directory of Open Access Journals (Sweden)
Sohaib Obeid
2017-01-01
Full Text Available An analysis of 2D subsonic flow over an NACA 0015 airfoil with a 30% trailing edge flap at a constant Reynolds number of 106 for various incidence angles and a range of flap deflections is presented. The steady-state governing equations of continuity and momentum conservation are solved combined with the realizable k-ε turbulence model using the ANSYS-Fluent code (Version 13.7, ANSYS, Inc., Canonsburg, PA, USA. The primary objective of the study is to provide a comprehensive understanding of flow characteristics around the NACA 0015 airfoil as a function of the angle of attack and flap deflection at Re = 106 using the realizable k-ε turbulence model. The results are validated through comparison of the predictions with the free field experimental measurements. Consistent with the experimental observations, the numerical results show that increased flap deflections increase the maximum lift coefficient, move the zero-lift angle of attack (AoA to a more negative value, decrease the stall AoA, while the slope of the lift curve remains unchanged and the curve just shifts upwards. In addition, the numerical simulations provide limits for lift increment Δ C l and Cl, max values to be 1.1 and 2.2, respectively, obtained at a flap deflection of 50°. This investigation demonstrates that the realizable k-ε turbulence model is capable of predicting flow features over an airfoil with and without flap deflections with reasonable accuracy.
Experimental studies of Reynolds number dependence of turbulent mixing & transport
Energy Technology Data Exchange (ETDEWEB)
Warhaft, Z. [Cornell Univ., Ithaca, NY (United States)
1996-12-31
An overview of recent experiments, in which the author generated high Reynolds number homogeneous grid turbulence, is provided. The author shows that in a small wind tunnel, Reynolds numbers that are sufficiently high (R{sub {lambda}} {approximately} 800, R{sub {ell}} {approximately} 36, 000) such that many of the aspects of turbulence that hitherto have only been observed in large scale anisotropic shear flows, are obtained. In particular the author studied the evolution of the spectrum with Reynolds number, the Kolmogorov constant and the internal intermittency, showing the way they tend to their high Reynolds number asymptotes. Thus the author links previous low Reynolds number laboratory experiments with large scale environmental measurements.
McNicholas, Patrick J.; Floyd, Randy G.
2017-01-01
The Reynolds Intellectual Assessment Scales, Second Edition (RIAS-2; Reynolds & Kamphaus, 2015) is an intelligence test for those aged 3 to 94 years. It contains eight subtests designed to assess general intelligence, verbal and nonverbal intelligence, memory, and processing speed. The two subtests targeting processing speed are new to the…
Wosnik, M.; Bachant, P.; Nedyalkov, I.; Rowell, M.; Dufresne, N.; Lyon, V.
2013-12-01
tall three-bladed cross-flow axis turbine (UNH RVAT) in a tow tank. For cross-flow axis turbines hydrofoil performance remains Reynolds number dependent at intermediate scales due to the large range of angles of attack encountered during turbine rotation. The experiments, with turbine diameter Reynolds numbers ReD = 0.5 x105 to 2.0 x106, were aimed at providing detailed data for model comparison at significantly higher Reynolds numbers than previously available. Measurements include rotor power, thrust, tip speed ratio, and detailed maps of mean flow and turbulence components in the near-wake. Mechanical exergy efficiency was calculated from power and drag measurements using an actuator disk approach. The spatial and temporal resolutions of different flow measurement techniques (ADCP, ADV, PIV) were systematically characterized. Finally, Reynolds-averaged Navier-Stokes (RANS) simulations were performed to assess their ability to predict the experimental results. A scaled version of a mixer-ejector hydrokinetic turbine, with a specially designed shroud to promotes wake mixing to enable increased mass flow through the turbine rotor, was evaluated experimentally at the UNH Tidal Energy Test Site in Great Bay Estuary, NH and in Muskeget Channel, MA. State-of-the-art instrumentation was used to measure the tidal energy resource and turbine wake flow velocities, turbine power extraction, test platform loadings and platform motion induced by sea state.
Holography of the QGP Reynolds number
Directory of Open Access Journals (Sweden)
Brett McInnes
2017-08-01
Full Text Available The viscosity of the Quark–Gluon Plasma (QGP is usually described holographically by the entropy-normalized dynamic viscosity η/s. However, other measures of viscosity, such as the kinematic viscosity ν and the Reynolds number Re, are often useful, and they too should be investigated from a holographic point of view. We show that a simple model of this kind puts an upper bound on Re for nearly central collisions at a given temperature; this upper bound is in very good agreement with the observational lower bound (from the RHIC facility. Furthermore, in a holographic approach using only Einstein gravity, η/s does not respond to variations of other physical parameters, while ν and Re can do so. In particular, it is known that the magnetic fields arising in peripheral heavy-ion collisions vary strongly with the impact parameter b, and we find that the holographic model predicts that ν and Re can also be expected to vary substantially with the magnetic field and therefore with b.
Holography of the QGP Reynolds number
McInnes, Brett
2017-08-01
The viscosity of the Quark-Gluon Plasma (QGP) is usually described holographically by the entropy-normalized dynamic viscosity η / s. However, other measures of viscosity, such as the kinematic viscosity ν and the Reynolds number Re, are often useful, and they too should be investigated from a holographic point of view. We show that a simple model of this kind puts an upper bound on Re for nearly central collisions at a given temperature; this upper bound is in very good agreement with the observational lower bound (from the RHIC facility). Furthermore, in a holographic approach using only Einstein gravity, η / s does not respond to variations of other physical parameters, while ν and Re can do so. In particular, it is known that the magnetic fields arising in peripheral heavy-ion collisions vary strongly with the impact parameter b, and we find that the holographic model predicts that ν and Re can also be expected to vary substantially with the magnetic field and therefore with b.
Directory of Open Access Journals (Sweden)
Caroline Hornung
2017-10-01
Full Text Available In the present study, we opted for a longitudinal design and examined rapid automatized naming (RAN performance from two perspectives. In a first step, we examined the structure of RAN performance from a general cognitive perspective. We investigated whether rapid naming measures (e.g., digit RAN and color RAN reflect a mainly domain-general factor or domain-specific factors. In a second step, we examined how the best fitting RAN model was related to reading and arithmetic outcomes, assessed several months later. Finally in a third step we took a clinical perspective and investigated specific contributions of RAN measures to reading and arithmetic outcomes. While RAN has emerged as a promising predictor of reading, the relationship between RAN and arithmetic has been less examined in the past. Hundred and twenty-two first graders completed seven RAN tasks, each comprising visually familiar stimuli such as digits, vowels, consonants, dice, finger-numeral configurations, objects, and colors. Four months later the same children completed a range of reading and arithmetic tasks. From a general descriptive perspective, structural equation modeling supports a one-dimensional RAN factor in 6- to -7-year-old children. However, from a clinical perspective, our findings emphasize the specific contributions of RANs. Interestingly, alphanumeric RANs (i.e., vowel RAN were most promising when predicting reading skills and number-specific RANs (i.e., finger-numeral configuration RAN were most promising when predicting arithmetic fluency. The implications for clinical and educational practices will be discussed.
Effect of Engine Installation on Jet Noise using a Hybrid LES/RANS Approach Project
National Aeronautics and Space Administration — Installation effects arising from propulsion airframe interaction are known to produce substantial variations in the in-situ jet noise. A hybrid LES/RANS...
The effect of roughness at high Reynolds numbers on the performance of aerofoil DU 97-W-300Mod
Energy Technology Data Exchange (ETDEWEB)
Timmer, W.A. [Delft Univ. (Netherlands). Wind Energy Inst.; Schaffarczyk, A.P. [University of Applied Sciences, Kiel (Germany). Dept. of Mechanical Engineering
2004-07-01
This article discusses the results of wind tunnel measurements performed on a modified DU 97-W-300 aerofoil at Reynolds numbers between 1 x 10{sup 6} and 10 x 10{sup 6} in the cryogenic wind tunnel of DNW in Koeln, Germany. The aerofoil was modified by reducing the trailing edge thickness from 1.74% to 0.49% of the chord. Although the measurements showed large scatter when flow separation occurred on the model, it was possible to establish the variation with Reynolds number of the maximum lift coefficient, the maximum lift/drag ratio and the design lift coefficient for a Mach number of 0.2. Furthermore, the effect of wrap-around Carborundum 60 roughness and zigzag tape of 0.4 mm thickness on the upper and lower surfaces was studied. The experimental results were compared with RFOIL calculations. The measurements indicate that there was no significant variation in the maximum lift coefficient with Reynolds number for the clean aerofoil. In contrast to the RFOIL calculations, the experimental maximum lift/drag ratio decreased with increasing Reynolds number from an average of 95 at R = 3 x 10{sup 6} to about 85 at R = 10 x 10{sup 6}. The Carborundum 60 roughness had a larger negative effect on the aerofoil performance than the zigzag tape, but in both cases the aerofoil performance improved drastically with increasing Reynolds number. (author)
DEFF Research Database (Denmark)
Gramkow, Claus
1999-01-01
In this article two common approaches to averaging rotations are compared to a more advanced approach based on a Riemannian metric. Very offten the barycenter of the quaternions or matrices that represent the rotations are used as an estimate of the mean. These methods neglect that rotations belong...... approximations to the Riemannian metric, and that the subsequent corrections are inherient in the least squares estimation. Keywords: averaging rotations, Riemannian metric, matrix, quaternion...
Averaging Schwarzschild spacetime
Tegai, S. Ph.; Drobov, I. V.
2017-07-01
We tried to average the Schwarzschild solution for the gravitational point source by analogy with the same problem in Newtonian gravity or electrostatics. We expected to get a similar result, consisting of two parts: the smoothed interior part being a sphere filled with some matter content and an empty exterior part described by the original solution. We considered several variants of generally covariant averaging schemes. The averaging of the connection in the spirit of Zalaletdinov's macroscopic gravity gave unsatisfactory results. With the transport operators proposed in the literature it did not give the expected Schwarzschild solution in the exterior part of the averaged spacetime. We were able to construct a transport operator that preserves the Newtonian analogy for the outward region but such an operator does not have a clear geometrical meaning. In contrast, using the curvature as the primary averaged object instead of the connection does give the desired result for the exterior part of the problem in a fine way. However for the interior part, this curvature averaging does not work because the Schwarzschild curvature components diverge as 1 /r3 near the center and therefore are not integrable.
Kate Watson on Reynold Humphries’ Hollywood’s Blacklists
Directory of Open Access Journals (Sweden)
2008-12-01
Full Text Available Reynold Humphries. Hollywood’s Blacklists: A Political and Cultural History. Edinburgh: Edinburgh University Press, 2008. Reynold Humphries’ Hollywood’s Blacklists provides a comprehensive examination of the historical and political ramifications of the blacklisting process and of Communism in the motion picture industry. His section on ‘The Background’ initially sets up just this, making the debate and dispute accessible even to those not au fait with such knowledge. This section is informat...
Energy Technology Data Exchange (ETDEWEB)
Gareau, Jaclyn R.; Reverter, David; Lima, Christopher D. (SKI)
2012-02-16
The RanBP2 nucleoporin contains an internal repeat domain (IR1-M-IR2) that catalyzes E3 ligase activity and forms a stable complex with SUMO-modified RanGAP1 and UBC9 at the nuclear pore complex. RanBP2 exhibits specificity for SUMO1 as RanGAP1-SUMO1/UBC9 forms a more stable complex with RanBP2 compared with RanGAP1-SUMO2 that results in greater protection of RanGAP-SUMO1 from proteases. The IR1-M-IR2 SUMO E3 ligase activity also shows a similar preference for SUMO1. We utilized deletions and domain swap constructs in protease protection assays and automodification assays to define RanBP2 domains responsible for RanGAP1-SUMO1 protection and SUMO1-specific E3 ligase activity. Our data suggest that elements in both IR1 and IR2 exhibit specificity for SUMO1. IR1 protects RanGAP1-SUMO1/UBC9 and functions as the primary E3 ligase of RanBP2, whereas IR2 retains the ability to interact with SUMO1 to promote SUMO1-specific E3 ligase activity. To determine the structural basis for SUMO1 specificity, a hybrid IR1 construct and IR1 were used to determine three new structures for complexes containing UBC9 with RanGAP1-SUMO1/2. These structures show more extensive contacts among SUMO, UBC9, and RanBP2 in complexes containing SUMO1 compared with SUMO2 and suggest that differences in SUMO specificity may be achieved through these subtle conformational differences.
Energy Technology Data Exchange (ETDEWEB)
Ichiguchi, Katsuji [National Inst. for Fusion Science, Toki, Gifu (Japan)
1998-08-01
A new reduced set of resistive MHD equations is derived by averaging the full MHD equations on specified flux coordinates, which is consistent with 3D equilibria. It is confirmed that the total energy is conserved and the linearized equations for ideal modes are self-adjoint. (author)
Young, Vershawn Ashanti
2004-01-01
"Your Average Nigga" contends that just as exaggerating the differences between black and white language leaves some black speakers, especially those from the ghetto, at an impasse, so exaggerating and reifying the differences between the races leaves blacks in the impossible position of either having to try to be white or forever struggling to…
Determining average yarding distance.
Roger H. Twito; Charles N. Mann
1979-01-01
Emphasis on environmental and esthetic quality in timber harvesting has brought about increased use of complex boundaries of cutting units and a consequent need for a rapid and accurate method of determining the average yarding distance and area of these units. These values, needed for evaluation of road and landing locations in planning timber harvests, are easily and...
Taghavifar, Hadi; Khalilarya, Shahram; Jafarmadar, Samad; Taghavifar, Hamid
2016-08-01
A multidimensional computational fluid dynamic code was developed and integrated with probability density function combustion model to give the detailed account of multiphase fluid flow. The vapor phase within injector domain is treated with Reynolds-averaged Navier-Stokes technique. A new parameter is proposed which is an index of plane-cut spray propagation and takes into account two parameters of spray penetration length and cone angle at the same time. It was found that spray propagation factor (SPI) tends to increase at lower r/ d ratios, although the spray penetration tends to decrease. The results of SPI obtained by empirical correlation of Hay and Jones were compared with the simulation computation as a function of respective r/ d ratio. Based on the results of this study, the spray distribution on plane area has proportional correlation with heat release amount, NO x emission mass fraction, and soot concentration reduction. Higher cavitation is attributed to the sharp edge of nozzle entrance, yielding better liquid jet disintegration and smaller spray droplet that reduces soot mass fraction of late combustion process. In order to have better insight of cavitation phenomenon, turbulence magnitude in nozzle and combustion chamber was acquired and depicted along with spray velocity.
Šíp, Viktor
2016-01-01
We present a description and validation of a finite volume solver aimed at solving the problems of microscale urban flows where vegetation is present. The solver is based on the five equation system of Reynolds-averaged Navier-Stokes equations for atmospheric boundary layer flows, which are complemented by the k-epsilon turbulence model. The vegetation is modelled as a porous zone, and the effects of the vegetation are included in the momentum and turbulence equations. A detailed dry deposition model is incorporated in the pollutant transport equation, allowing the investigation of the filtering properties of urban vegetation. The solver is validated on four test cases to assess the components of the model: the flow and pollutant dispersion around the 2D hill, the temporal evolution of the rising thermal bubble, the flow through and around the forest canopy, and a hedgerow filtering the particle-laden flow. Generally good agreement with the measured values or previously computed numerical solution is observed...
Turbulence Model Effects on RANS Simulations of the HIFiRE Flight 2 Ground Test Configurations
Georgiadis, Nicholas J.; Mankbadi, Mina R.; Vyas, Manan A.
2014-01-01
The Wind-US Reynolds-averaged Navier-Stokes solver was applied to the Hypersonic International Flight Research Experimentation (HIFiRE) Flight 2 scramjet ground test configuration. Two test points corresponding to flight Mach numbers of 5.9 and 8.9 were examined. The emphasis was examining turbulence model effects on the prediction of flow path pressures. Three variants of the Menter k-omega turbulence model family were investigated. These include the baseline (BSL) and shear stress transport (SST) as well as a modified SST model where the shear stress limiter was altered. Variations in the turbulent Schmidt number were also considered. Choice of turbulence model had a substantial effect on prediction of the flow path pressures. The BSL model produced the highest pressures and the SST model produced the lowest pressures. As expected, the settings for the turbulent Schmidt number also had significant effects on predicted pressures. Small values for the turbulent Schmidt number enabled more rapid mass transfer, faster combustion, and in turn higher flowpath pressures. Optimal settings for turbulence model and turbulent Schmidt number were found to be rather case dependent, as has been concluded in other scramjet investigations.
Alimi, Isiaka A.; Monteiro, Paulo P.; Teixeira, António L.
2017-11-01
The key paths toward the fifth generation (5G) network requirements are towards centralized processing and small-cell densification systems that are implemented on the cloud computing-based radio access networks (CC-RANs). The increasing recognitions of the CC-RANs can be attributed to their valuable features regarding system performance optimization and cost-effectiveness. Nevertheless, realization of the stringent requirements of the fronthaul that connects the network elements is highly demanding. In this paper, considering the small-cell network architectures, we present multiuser mixed radio-frequency/free-space optical (RF/FSO) relay networks as feasible technologies for the alleviation of the stringent requirements in the CC-RANs. In this study, we use the end-to-end (e2e) outage probability, average symbol error probability (ASEP), and ergodic channel capacity as the performance metrics in our analysis. Simulation results show the suitability of deployment of mixed RF/FSO schemes in the real-life scenarios.
Covariant approximation averaging
Shintani, Eigo; Blum, Thomas; Izubuchi, Taku; Jung, Chulwoo; Lehner, Christoph
2014-01-01
We present a new class of statistical error reduction techniques for Monte-Carlo simulations. Using covariant symmetries, we show that correlation functions can be constructed from inexpensive approximations without introducing any systematic bias in the final result. We introduce a new class of covariant approximation averaging techniques, known as all-mode averaging (AMA), in which the approximation takes account of contributions of all eigenmodes through the inverse of the Dirac operator computed from the conjugate gradient method with a relaxed stopping condition. In this paper we compare the performance and computational cost of our new method with traditional methods using correlation functions and masses of the pion, nucleon, and vector meson in $N_f=2+1$ lattice QCD using domain-wall fermions. This comparison indicates that AMA significantly reduces statistical errors in Monte-Carlo calculations over conventional methods for the same cost.
Covariant approximation averaging
Shintani, Eigo; Arthur, Rudy; Blum, Thomas; Izubuchi, Taku; Jung, Chulwoo; Lehner, Christoph
2015-06-01
We present a new class of statistical error reduction techniques for Monte Carlo simulations. Using covariant symmetries, we show that correlation functions can be constructed from inexpensive approximations without introducing any systematic bias in the final result. We introduce a new class of covariant approximation averaging techniques, known as all-mode averaging (AMA), in which the approximation takes account of contributions of all eigenmodes through the inverse of the Dirac operator computed from the conjugate gradient method with a relaxed stopping condition. In this paper we compare the performance and computational cost of our new method with traditional methods using correlation functions and masses of the pion, nucleon, and vector meson in Nf=2 +1 lattice QCD using domain-wall fermions. This comparison indicates that AMA significantly reduces statistical errors in Monte Carlo calculations over conventional methods for the same cost.
Rogers, Thomas W.
1988-01-01
Digital electronic filtering system produces series of moving-average samples of fluctuating signal in manner resulting in removal of undesired periodic signal component of known frequency. Filter designed to pass steady or slowly varying components of fluctuating pressure, flow, pump speed, and pump torque in slurry-pumping system. Concept useful for monitoring or control in variety of applications including machinery, power supplies, and scientific instrumentation.
Averaging operations on matrices
Indian Academy of Sciences (India)
2014-07-03
Jul 3, 2014 ... Arithmetic mean of objects in a space need not lie in the space. [Frechet; 1948] Finding mean of right-angled triangles. S = {(x,y,z) ∈ R+3 : x2 + y2 = z2}. = {. [ z x − ιy x + ιy z. ] : x,y,z > 0,z2 = x2 + y2}. Surface of right triangles : Arithmetic mean not on S. Tanvi Jain. Averaging operations on matrices ...
Haydn, N; Lunedei, E; Vaienti, S
2007-09-01
We introduce a new indicator for dynamical systems, namely the averaged number of visits, to estimate the frequency of visits in small regions when a map is iterated up to the inverse of the measure of this region. We compute this quantity analytically and numerically for various systems and we show that it depends on the ergodic properties of the systems and on their topological properties, such as the presence of periodic points.
Rapid automatized naming (RAN) in children with ADHD: An ex-Gaussian analysis.
Ryan, Matthew; Jacobson, Lisa A; Hague, Cole; Bellows, Alison; Denckla, Martha B; Mahone, E Mark
2017-07-01
Children with ADHD demonstrate increased frequent "lapses" in performance on tasks in which the stimulus presentation rate is externally controlled, leading to increased variability in response times. It is less clear whether these lapses are also evident during performance on self-paced tasks, e.g., rapid automatized naming (RAN), or whether RAN inter-item pause time variability uniquely predicts reading performance. A total of 80 children aged 9 to 14 years-45 children with attention-deficit/hyperactivity disorder (ADHD) and 35 typically developing (TD) children-completed RAN and reading fluency measures. RAN responses were digitally recorded for analyses. Inter-stimulus pause time distributions (excluding between-row pauses) were analyzed using traditional (mean, standard deviation [SD], coefficient of variation [CV]) and ex-Gaussian (mu, sigma, tau) methods. Children with ADHD were found to be significantly slower than TD children (p reading fluency. RAN response time distributions were also significantly more variable (SD, tau) in children with ADHD. Hierarchical regression revealed that the exponential component (tau) of the letter-naming response time distribution uniquely predicted reading fluency in children with ADHD (p reading, ADHD symptom severity and age. The findings suggest that children with ADHD (without word-level reading difficulties) manifest slowed performance on tasks of reading fluency; however, this "slowing" may be due in part to lapses from ongoing performance that can be assessed directly using ex-Gaussian methods that capture excessively long response times.
Pulsatility role in cylinder flow dynamics at low Reynolds number
Qamar, Adnan
2012-01-01
We present dynamics of pulsatile flow past a stationary cylinder characterized by three non-dimensional parameters: the Reynolds number (Re), non-dimensional amplitude (A) of the pulsatile flow velocity, and Keulegan-Carpenter number (KC = Uo/Dωc). This work is motivated by the development of total artificial lungs (TAL) device, which is envisioned to provide ambulatory support to patients. Results are presented for 0.2 ≤ A ≤ 0.6 and 0.57 ≤ KC ≤ 2 at Re = 5 and 10, which correspond to the operating range of TAL. Two distinct fluid regimes are identified. In both regimes, the size of the separated zone is much greater than the uniform flow case, the onset of separation is function of KC, and the separation vortex collapses rapidly during the last fraction of the pulsatile cycle. The vortex size is independent of KC, but with an exponential dependency on A. In regime I, the separation point remains attached to the cylinder surface. In regime II, the separation point migrates upstream of the cylinder. Two distinct vortex collapse mechanisms are observed. For A < 0.4 and all KC and Re values, collapse occurs on the cylinder surface, whereas for A > 0.4 the separation vortex detaches from the cylinder surface and collapses at a certain distance downstream of the cylinder. The average drag coefficient is found to be independent of A and KC, and depends only on Re. However, for A > 0.4, for a fraction of the pulsatile cycle, the instantaneous drag coefficient is negative indicating a thrust production. © 2012 American Institute of Physics.
Does ability to establish sound-symbol pairings mediate the RAN reading relationship?
DEFF Research Database (Denmark)
Poulsen, Mads; Juul, Holger; Elbro, Carsten
for animals in a paired associate learning task. These animals were then used in a rapid naming task. Results Preliminary results show that reading correlated with the amount of training required for learning the animal names (r=-.19, p=.06). RAN speed with the same animals did not correlate with reading......Performance on tests to rapidly name letters and digits has been shown to correlate with reading. One possible reason is that these tests probe the ability to learn and automatise symbol-sound associations. However, most studies have not controlled for the amount of experience with the RAN......-items, so it is unclear whether it is the experience or the ability to take advantage of the experience that is responsible for the correlation between RAN and reading. Paired associate learning tasks have been shown to differentiate dyslexics from controls, and to correlate with reading in unselected...
Model-Invariant Hybrid LES-RANS Computation of Separated Flow Past Periodic Hills
Woodruff, Stephen
2014-01-01
The requirement that physical quantities not vary with a hybrid LESRANS model's blending parameter imposes conditions on the computation that lead to better results across LES-RANS transitions. This promises to allow placement of those transitions so that LES is performed only where required by the physics, improving computational efficiency. The approach is applied to separated flow past periodic hills, where good predictions of separation-bubble size are seen due to the gradual, controlled, LES-RANS transition and the resulting enhanced near-wall eddy viscosity.
High-fidelity simulations of moving and flexible airfoils at low Reynolds numbers
Energy Technology Data Exchange (ETDEWEB)
Visbal, Miguel R.; Gordnier, Raymond E.; Galbraith, Marshall C. [Air Force Research Laboratory, Computational Sciences Branch, Air Vehicles Directorate, Wright-Patterson AFB, OH (United States)
2009-05-15
The present paper highlights results derived from the application of a high-fidelity simulation technique to the analysis of low-Reynolds-number transitional flows over moving and flexible canonical configurations motivated by small natural and man-made flyers. This effort addresses three separate fluid dynamic phenomena relevant to small fliers, including: laminar separation and transition over a stationary airfoil, transition effects on the dynamic stall vortex generated by a plunging airfoil, and the effect of flexibility on the flow structure above a membrane airfoil. The specific cases were also selected to permit comparison with available experimental measurements. First, the process of transition on a stationary SD7003 airfoil section over a range of Reynolds numbers and angles of attack is considered. Prior to stall, the flow exhibits a separated shear layer which rolls up into spanwise vortices. These vortices subsequently undergo spanwise instabilities, and ultimately breakdown into fine-scale turbulent structures as the boundary layer reattaches to the airfoil surface. In a time-averaged sense, the flow displays a closed laminar separation bubble which moves upstream and contracts in size with increasing angle of attack for a fixed Reynolds number. For a fixed angle of attack, as the Reynolds number decreases, the laminar separation bubble grows in vertical extent producing a significant increase in drag. For the lowest Reynolds number considered (Re{sub c} = 10 {sup 4}), transition does not occur over the airfoil at moderate angles of attack prior to stall. Next, the impact of a prescribed high-frequency small-amplitude plunging motion on the transitional flow over the SD7003 airfoil is investigated. The motion-induced high angle of attack results in unsteady separation in the leading edge and in the formation of dynamic-stall-like vortices which convect downstream close to the airfoil. At the lowest value of Reynolds number (Re{sub c}=10 {sup 4
Green, Katelyn M; Glineburg, M Rebecca; Kearse, Michael G; Flores, Brittany N; Linsalata, Alexander E; Fedak, Stephen J; Goldstrohm, Aaron C; Barmada, Sami J; Todd, Peter K
2017-12-08
Repeat-associated non-AUG (RAN) translation allows for unconventional initiation at disease-causing repeat expansions. As RAN translation contributes to pathogenesis in multiple neurodegenerative disorders, determining its mechanistic underpinnings may inform therapeutic development. Here we analyze RAN translation at G4C2 repeat expansions that cause C9orf72-associated amyotrophic lateral sclerosis and frontotemporal dementia (C9RAN) and at CGG repeats that cause fragile X-associated tremor/ataxia syndrome. We find that C9RAN translation initiates through a cap- and eIF4A-dependent mechanism that utilizes a CUG start codon. C9RAN and CGG RAN are both selectively enhanced by integrated stress response (ISR) activation. ISR-enhanced RAN translation requires an eIF2α phosphorylation-dependent alteration in start codon fidelity. In parallel, both CGG and G4C2 repeats trigger phosphorylated-eIF2α-dependent stress granule formation and global translational suppression. These findings support a model whereby repeat expansions elicit cellular stress conditions that favor RAN translation of toxic proteins, creating a potential feed-forward loop that contributes to neurodegeneration.
DEFF Research Database (Denmark)
Gramkow, Claus
2001-01-01
In this paper two common approaches to averaging rotations are compared to a more advanced approach based on a Riemannian metric. Very often the barycenter of the quaternions or matrices that represent the rotations are used as an estimate of the mean. These methods neglect that rotations belong...... to a non-linear manifold and re-normalization or orthogonalization must be applied to obtain proper rotations. These latter steps have been viewed as ad hoc corrections for the errors introduced by assuming a vector space. The article shows that the two approximative methods can be derived from natural...... approximations to the Riemannian metric, and that the subsequent corrections are inherent in the least squares estimation....
Effect of Fin Porosity on Wake Geometry for Flapping Fins at Intermediate Reynolds Number
Chen, J.; Xia, B.; Krueger, P. S.
2017-11-01
Low aspect ratio flapping fins generate interesting 3-dimensional flow structures as has been observed, for example, in studies of fish swimming. As the Reynolds number is reduced, the exact geometry of the fin is less important and even certain amounts of porosity might be allowed without significantly affecting propulsive performance. These effects are investigated experimentally using flapping rectangular fins of aspect ratio 2 at Reynolds numbers in the range 100 - 1000. The experiments were conducted using a water tunnel to supply the free stream flow and the fin flapping parameters were set to provide a Strouhal number (based on amplitude of the fin tip motion) in the range 0.15 - 0.35. Phase-averaged measurements were made of the 3-dimensional, volumetric flow field, allowing visualization of the typical shed vortex structure behind the fin and calculation of time averaged thrust and propulsive efficiency. Results comparing the flow structure in the fin wake and the resulting propulsive performance will be presented for several fins with different planform porosities where the porosities are set using arrays of holes in the fins. This material is based on the work supported by the National Science Foundation under Grant No. 1510707.
Inadequacy representation of flamelet-based RANS model for turbulent non-premixed flame
Lee, Myoungkyu; Oliver, Todd; Moser, Robert
2017-11-01
Stochastic representations for model inadequacy in RANS-based models of non-premixed jet flames are developed and explored. Flamelet-based RANS models are attractive for engineering applications relative to higher-fidelity methods because of their low computational costs. However, the various assumptions inherent in such models introduce errors that can significantly affect the accuracy of computed quantities of interest. In this work, we develop an approach to represent the model inadequacy of the flamelet-based RANS model. In particular, we pose a physics-based, stochastic PDE for the triple correlation of the mixture fraction. This additional uncertain state variable is then used to construct perturbations of the PDF for the instantaneous mixture fraction, which is used to obtain an uncertain perturbation of the flame temperature. A hydrogen-air non-premixed jet flame is used to demonstrate the representation of the inadequacy of the flamelet-based RANS model. This work was supported by DARPA-EQUiPS(Enabling Quantification of Uncertainty in Physical Systems) program.
Optimal Assignment of Cells in C-RAN Deployments with Multiple BBU Pools
DEFF Research Database (Denmark)
Holm, Henrik; Checko, Aleksandra; Al-obaidi, Rami
2015-01-01
recommend to divide the area into multiple BBU Pools. In this paper we show how to optimally assign cells to different BBU Pools in such a scenario. By using Integer Linear Programming (ILP) method we derive engineering guidelines for minimizing the CAPital EXpenditure (CAPEX) of C-RAN deployment....
Western Culture in Japanese Film: Kurosawa's "Throne of Blood" and "Ran."
Kane, Peter E.
Akira Kurosawa, the most popular Asian film maker with audiences in the United States, has found in William Shakespeare's plays themes and plots that resonate within Japanese culture. While the translations of "Macbeth" into "Throne of Blood" and "King Lear" into "Ran" are quite direct and literal with only…
Optimizing Cloud-RAN Deployments in Real-life Scenarios Using Microwave Radio
DEFF Research Database (Denmark)
Al-obaidi, Rami; Checko, Aleksandra; Holm, Henrik
2015-01-01
derive engineering guidelines for minimizing the CAPital EXpenditure (CAPEX) of C-RAN deployment. We show for which population density and span of BBU Pool coverage usage of Microwave Radio (MWR) links is viable. For larger scale deployment we recommend to divide the area into multiple BBU Pools....
Ardo Ran Varres elustab härra Tartüffi / Tiit Tuumalu
Tuumalu, Tiit, 1971-
2005-01-01
2.-9. septembrini Pärnus, Haapsalus, Tallinnas, Viljandis ja Tartus toimuvast tummfilmi ühe olulisema lavastaja F. W. Murnau "Tartüff" filmikontserdist "Tartüff live", esitaja Varrese ansambel ARV Ensemble. Ardo Ran Varrese töödest
Stokesian swimming of a sphere at low Reynolds number
Felderhof, B U
2016-01-01
Explicit expressions are derived for the matrices determining the mean translational and rotational swimming velocities and the mean rate of dissipation for Stokesian swimming at low Reynolds number of a distorting sphere in a viscous incompressible fluid. As an application an efficient helical propeller-type stroke is found and its properties are calculated.
High Reynolds number liquid layer flow with flexible walls
Indian Academy of Sciences (India)
Permanent link: http://www.ias.ac.in/article/fulltext/sadh/040/03/0961-0972. Keywords. Stability; triple-deck; separation; boundary-layer; compliant wall. Abstract. The stability of liquid layer flow over an inclined flexible wall is studied using asymptotic methods based on the assumption that the Reynolds number is large.
Reynolds number effect on VIV: from subcritical to supercritical flow
Energy Technology Data Exchange (ETDEWEB)
Triantafyllou, M.S.; Hover, F.S.; Techet, A.H. [Massachusetts Inst. of Tech., Dept. of Ocean Engineering, Cambridge, MA (United States)
2004-07-01
Vortex Induced Vibrations in flexibly supported rigid cylinders and long, flexible slender structures, such as cables and risers, are caused by the formation of large-scale vortices, whose dynamics are controlled to a large extend by inviscid mechanisms. Reynolds number remains a very important parameter, however, because it influences the formation and shedding mechanisms of the vortical patterns. For low Reynolds numbers, below a few thousand, a nearly complete understanding has been obtained in recent years, at least for flexibly mounted rigid cylinders. This is not the case, though, for VIV above Re=10,000 and - especially - above the critical Reynolds number of about Re=250,000 for smooth cylinders. The talk provides observed WV trends of flexibly mounted cylinders, obtained in recent experiments as function of the Reynolds number, from Re about 1,000 up to 1,000,000. In particular, similarities and differences between subcritical and supercritical force and motion data will be discussed, and conclusions on the governing principal mechanisms will be drawn, including transitions in the arrangement of vortical patterns and effects of correlation length. (authors)
Bifurcation to forward flapping flight at intermediate Reynolds number.
Vandenberghe, Nicolas; Zhang, Jun; Childress, Stephen
2003-11-01
The locomotion of most fish and birds is realized by flapping wings or fins transverse to the direction of travel. According to early theoretical studies, a flapping wing translating at finite speed in an inviscid fluid experiences a propulsive force. In steady forward flight this thrust is balanced by drag. Such "lift-based mechanisms" of thrust production are characteristic of the Eulerian realm, where discrete vortical structures are shed. But, when the Reynolds number is small, viscous forces dominate and reciprocal flapping motions are ineffective. A flapping wing experiences a net drag and cannot be used to propel an organism. We have devised an experiment to bridge the two regimes, and to examine the transition to forward flight at intermediate Reynolds numbers. We study the dynamics of an horizontal wing that is flapped up and down and is free to move either forwards or backwards. This very simple kinematics emphasizes the demarcation between low and high Reynolds number because it is effective in the Eulerian realm but has no effect in the Stokesian realm. We show that flapping flight occurs abruptly as a symmetry breaking bifurcation at a critical flapping frequency. Beyond the bifurcation the forward speed increases linearly with the flapping frequency. The experiment establishes a clear demarcation between the different strategies of locomotion at large and small Reynolds number.
Probability density distribution of velocity differences at high Reynolds numbers
Praskovsky, Alexander A.
1993-01-01
Recent understanding of fine-scale turbulence structure in high Reynolds number flows is mostly based on Kolmogorov's original and revised models. The main finding of these models is that intrinsic characteristics of fine-scale fluctuations are universal ones at high Reynolds numbers, i.e., the functional behavior of any small-scale parameter is the same in all flows if the Reynolds number is high enough. The only large-scale quantity that directly affects small-scale fluctuations is the energy flux through a cascade. In dynamical equilibrium between large- and small-scale motions, this flux is equal to the mean rate of energy dissipation epsilon. The pdd of velocity difference is a very important characteristic for both the basic understanding of fully developed turbulence and engineering problems. Hence, it is important to test the findings: (1) the functional behavior of the tails of the probability density distribution (pdd) represented by P(delta(u)) is proportional to exp(-b(r) absolute value of delta(u)/sigma(sub delta(u))) and (2) the logarithmic decrement b(r) scales as b(r) is proportional to r(sup 0.15) when separation r lies in the inertial subrange in high Reynolds number laboratory shear flows.
On Reynolds stress and neutral azimuthal modes in the stability ...
Indian Academy of Sciences (India)
For singular neutral modes it is shown that the Reynolds stress varies like the inverse square of the radial distance in agreement with the homogeneous flow result of Maslowe & Nigam. It is also proved that singular neutral modes do not exist whenever the value of the Richardson number at the critical layer exceeds one ...
Compressible Reynolds equation for high-pressure gases
Chien, S. Y.; Cramer, M. S.; Untaroiu, A.
2017-11-01
We derive the Reynolds equation corresponding to steady, laminar, two-dimensional, compressible flows of single-phase Navier-Stokes fluids in a thin gap between a stationary surface and one translating with constant speed. The thermodynamic state of the fluid is taken to be in the dense and supercritical gas regimes. The equation of state is a well-known cubic equation, and the shear viscosity and thermal conductivity are taken to depend on density and temperature. Thermal boundary conditions are taken to include those for constant-temperature and adiabatic walls. The flow is seen to be governed by both the speed number and a single thermodynamic parameter referred to as the effective bulk modulus. Numerical solutions to the Reynolds equation are compared to those of the full Navier-Stokes equations. It is shown that the Reynolds equation breaks down in the vicinity of the thermodynamic critical point. Furthermore, we show that energy convection is negligible whenever the Reynolds equation is valid which enables us to present new explicit solutions for the temperature distributions.
Göran Bonde - landsköpman och bondeseglare på 1500-talet / Bengt Eriksson
Eriksson, Bengt
2012-01-01
Üle Soome lahe kaubandusest 16. sajandil. Helsingi kihelkonnas tegutsenud kaupmehest Göran Bondest, kes käis aastas 5-6 korda kaubareisil Tallinnas. Tihedamad suhted sidusid Göran Bondet Tallinna kaupmehe Hemlich Fickega. "Läänemere valitsejast" Sören Norrbyst. Helsingi rajamisest Gustav I Vasa poolt vastukaaluks Tallinnale
Reynolds number effects on scale energy balance in wall turbulence
Saikrishnan, Neelakantan; De Angelis, Elisabetta; Longmire, Ellen K.; Marusic, Ivan; Casciola, Carlo M.; Piva, Renzo
2012-01-01
The scale energy budget utilizes a modified version of the classical Kolmogorov equation of wall turbulence to develop an evolution equation for the second order structure function [R. J. Hill, "Exact second-order structure-function relationships," J. Fluid Mech. 468, 317 (2002)]. This methodology allows for the simultaneous characterization of the energy cascade and spatial fluxes in turbulent shear flows across the entire physical domain as well as the range of scales. The present study utilizes this methodology to characterize the effects of Reynolds number on the balance of energy fluxes in turbulent channel flows. Direct numerical simulation data in the range Reτ = 300-934 are compared to previously published results at Reτ = 180 [N. Marati, C. M. Casciola, and R. Piva, "Energy cascade and spatial fluxes in wall turbulence," J. Fluid Mech. 521, 191 (2004)]. The present results show no Reynolds number effects in the terms of the scale energy budget in either the viscous sublayer or buffer regions of the channel. In the logarithmic layer, the transfer of energy across scales clearly varies with Reynolds number, while the production of turbulent kinetic energy is not dependent on Reynolds number. An envelope of inverse energy cascade is quantified in the buffer region within which energy is transferred from small to larger scales. This envelope is observed in the range 6 < y+ < 37, where all scales except the smallest scales display characteristics of an inverse energy cascade. The cross-over scale lc+, which indicates the transition between production dominated and scale transfer dominated regimes, increases with Reynolds number, implying a larger range of transfer dominated scales, before the dominant mechanism switches to production. At higher Reynolds numbers, two distinct regimes of lc+ as a function of wall-normal location are observed, which was not captured at Reτ = 180. The variations of lc+ match the trends of the shear scale, which is a
2008-09-01
been successfully used in many cases, their application is limited to structured meshes. To minimize mesh generation ef- fort for complex geometries...ν̃ S̃κ2d2 , where d is the distance to the nearest wall, cb1 = 0.1355, σ = 2/3, cb2 = 0.622, κ = 0.41, cw1 = cb1 /κ 2+(1+cb2)/σ, cw2 = 0.3, cw3 = 2... structured mesh. The actual error is computed relative to the drag from a p = 3 solution on a 8170 element mesh generated by taking an additional p = 3
Energy Technology Data Exchange (ETDEWEB)
Laskowski, Gregory Michael
2005-12-01
Flows with strong curvature present a challenge for turbulence models, specifically eddy viscosity type models which assume isotropy and a linear and instantaneous equilibrium relation between stress and strain. Results obtained from three different codes and two different linear eddy viscosity turbulence models are compared to a DNS simulation in order to gain some perspective on the turbulence modeling capability of SIERRA/Fuego. The Fuego v2f results are superior to the more common two-layer k-e model results obtained with both a commercial and research code in terms of the concave near wall behavior predictions. However, near the convex wall, including the separated region, little improvement is gained using the v2f model and in general the turbulent kinetic energy prediction is fair at best.
Viscous decay of nonlinear oscillations of a spherical bubble at large Reynolds number
Smith, W. R.; Wang, Q. X.
2017-08-01
The long-time viscous decay of large-amplitude bubble oscillations is considered in an incompressible Newtonian fluid, based on the Rayleigh-Plesset equation. At large Reynolds numbers, this is a multi-scaled problem with a short time scale associated with inertial oscillation and a long time scale associated with viscous damping. A multi-scaled perturbation method is thus employed to solve the problem. The leading-order analytical solution of the bubble radius history is obtained to the Rayleigh-Plesset equation in a closed form including both viscous and surface tension effects. Some important formulae are derived including the following: the average energy loss rate of the bubble system during each cycle of oscillation, an explicit formula for the dependence of the oscillation frequency on the energy, and an implicit formula for the amplitude envelope of the bubble radius as a function of the energy. Our theory shows that the energy of the bubble system and the frequency of oscillation do not change on the inertial time scale at leading order, the energy loss rate on the long viscous time scale being inversely proportional to the Reynolds number. These asymptotic predictions remain valid during each cycle of oscillation whether or not compressibility effects are significant. A systematic parametric analysis is carried out using the above formula for the energy of the bubble system, frequency of oscillation, and minimum/maximum bubble radii in terms of the Reynolds number, the dimensionless initial pressure of the bubble gases, and the Weber number. Our results show that the frequency and the decay rate have substantial variations over the lifetime of a decaying oscillation. The results also reveal that large-amplitude bubble oscillations are very sensitive to small changes in the initial conditions through large changes in the phase shift.
Directory of Open Access Journals (Sweden)
Marc Vorpahl
Full Text Available Differentiation and dedifferentiation, accompanied by proliferation play a pivotal role for the phenotypic development of vascular proliferative diseases (VPD, such as restenosis. Increasing evidence points to an essential role of regulated nucleoporin expression in the choice between differentiation and proliferation. However, whether components of the Ran GTPase cycle, which is of pivotal importance for both nucleocytoplasmic transport and for mitotic progression, are subject to similar regulation in VPD is currently unknown. Here, we show that differentiation of human coronary artery smooth muscle cell (CASMC to a contractile phenotype by stepwise serum depletion leads to significant reduction of RanGAP1 protein levels. The inverse event, dedifferentiation of cells, was assessed in the rat carotid artery balloon injury model, a well-accepted model for neointima formation and restenosis. As revealed by temporospatial analysis of RanGAP1 expression, neointima formation in rat carotid arteries was associated with a significant upregulation of RanGAP1 expression at 3 and 7 days after balloon injury. Of note, neointimal cells located at the luminal surface revealed persistent RanGAP1 expression, as opposed to cells in deeper layers of the neointima where RanGAP1 expression was less or not detectable at all. To gain first evidence for a direct influence of RanGAP1 levels on differentiation, we reduced RanGAP1 in human coronary artery smooth muscle cells by siRNA. Indeed, downregulation of the essential RanGAP1 protein by 50% induced a differentiated, spindle-like smooth muscle cell phenotype, accompanied by an upregulation of the differentiation marker desmin. Reduction of RanGAP1 levels also resulted in a reduction of mitogen induced cellular migration and proliferation as well as a significant upregulation of the cyclin-dependent kinase inhibitor p27KIP1, without evidence for cellular necrosis. These findings suggest that RanGAP1 plays a critical
Vorpahl, Marc; Schönhofer-Merl, Sabine; Michaelis, Cornelia; Flotho, Annette; Melchior, Frauke; Wessely, Rainer
2014-01-01
Differentiation and dedifferentiation, accompanied by proliferation play a pivotal role for the phenotypic development of vascular proliferative diseases (VPD), such as restenosis. Increasing evidence points to an essential role of regulated nucleoporin expression in the choice between differentiation and proliferation. However, whether components of the Ran GTPase cycle, which is of pivotal importance for both nucleocytoplasmic transport and for mitotic progression, are subject to similar regulation in VPD is currently unknown. Here, we show that differentiation of human coronary artery smooth muscle cell (CASMC) to a contractile phenotype by stepwise serum depletion leads to significant reduction of RanGAP1 protein levels. The inverse event, dedifferentiation of cells, was assessed in the rat carotid artery balloon injury model, a well-accepted model for neointima formation and restenosis. As revealed by temporospatial analysis of RanGAP1 expression, neointima formation in rat carotid arteries was associated with a significant upregulation of RanGAP1 expression at 3 and 7 days after balloon injury. Of note, neointimal cells located at the luminal surface revealed persistent RanGAP1 expression, as opposed to cells in deeper layers of the neointima where RanGAP1 expression was less or not detectable at all. To gain first evidence for a direct influence of RanGAP1 levels on differentiation, we reduced RanGAP1 in human coronary artery smooth muscle cells by siRNA. Indeed, downregulation of the essential RanGAP1 protein by 50% induced a differentiated, spindle-like smooth muscle cell phenotype, accompanied by an upregulation of the differentiation marker desmin. Reduction of RanGAP1 levels also resulted in a reduction of mitogen induced cellular migration and proliferation as well as a significant upregulation of the cyclin-dependent kinase inhibitor p27KIP1, without evidence for cellular necrosis. These findings suggest that RanGAP1 plays a critical role in smooth
Evaluating C-RAN Fronthaul Functional Splits in Terms of Network Level Energy and Cost Savings
DEFF Research Database (Denmark)
Checko, Aleksandra; Popovska Avramova, Andrijana; Berger, Michael Stübert
2016-01-01
split in the baseband processing chain has been proposed to overcome these challenges. This paper evaluates, by mathematical and simulation methods, different splits with respect to network level energy and cost efficiency having in the mind the expected quality of service.The proposed mathematical......The placement of the complete baseband processing in a centralized pool results in high data rate requirement and inflexibility of the fronthaul network, which challenges the energy and cost effectiveness of the cloud radio access network (C-RAN). Recently, redesign of the C-RAN through functional...... model quantifies the multiplexing gains and the trade-offs between centralization and decentralization concerning the cost of the pool, fronthaul network capacity and resource utilization. The event-based simulation captures the influence of the traffic load dynamics and traffic type variation...
Enhancing LTE with Cloud-RAN and Load-Controlled Parasitic Antenna Arrays
DEFF Research Database (Denmark)
Artuso, Matteo; Boviz, Dora; Checko, Aleksandra
2016-01-01
implementations of C-RANs tackle fundamental technical and economic challenges. In this article, we present an end-to-end solution for practically implementable C-RANs by providing innovative solutions to key issues such as the design of cost-effective hardware and power-effective signals for RRHs, efficient...... design and distribution of data and control traffic for coordinated communications, and conception of a flexible and elastic architecture supporting dynamic allocation of both the densely distributed RRHs and the centralized processing resources in the cloud to create virtual base stations. More...... specifically, we propose a novel antenna array architecture called load-controlled parasitic antenna array (LCPAA) where multiple antennas are fed by a single RF chain. Energy- and spectral-efficient modulation as well as signaling schemes that are easy to implement are also provided. Additionally, the design...
Energy Technology Data Exchange (ETDEWEB)
Cardenas, Camilo [Karlsruhe Institute of Technology, Institute for Chemical Technology and Polymer Chemistry, Karlsruhe (Germany); Convenio Andres Bello, Instituto Internacional de Investigaciones Educativas para la Integracion, La Paz (Bolivia); Denev, Jordan A.; Bockhorn, Henning [Karlsruhe Institute of Technology, Engler-Bunte-Institute, Combustion Division, Karlsruhe (Germany); Suntz, Rainer [Karlsruhe Institute of Technology, Institute for Chemical Technology and Polymer Chemistry, Karlsruhe (Germany)
2012-10-15
experiments of a straight jet into a co-flow. Mixing is further studied by means of second-order statistics of the passive scalar variance and the Reynolds fluxes. Windward and leeward sides of the jet exhibit different signs for the time-averaged streamwise Reynolds flux left angle v{sub x}'c' right angle. The large coherent structures which contribute to this effect are investigated by means of timely correlated instantaneous PIV-LIF camera snapshots and their contribution to the average statistics of left angle v{sub x}'c' right angle are discussed. The discussion on mixing capabilities of the jet in cross-flow is supported by simulation results showing the instantaneous three-dimensional coherent structures defined in terms of the pressure fluctuations. (orig.)
Application of Les, Pans and Rans to a Case of Intake Channel Steady Flow Test Bench
Directory of Open Access Journals (Sweden)
Vítek Oldřich
2015-12-01
Full Text Available The paper deals with evaluation of intake channel flow properties (discharge coefficient, tumble and swirl ratio using both 3-D CFD simulation and measurement. Sensitivity of different calculation parameters was tested. The most important ones are mesh parameters and applied turbulence models (considered models: LES, PANS and RANS. Concerning the mesh, the critical parameter is a mesh configuration near a wall - a thickness of mesh boundary layer and an amount of these layers have significant impact on mass flow rate while tumble/swirl ratio is unaffected by that. Based on that, these mesh parameters can be considered as tuning constants for fine-tuning the CFD model. Regarding the mesh cell size, 2 different values were tested (0.6 and 0.3 mm. It was found out that neither mesh is fine enough to perform proper LES. Hence, PANS performance is close to RANS. Concerning the turbulence models, PANS seems to be the best one as it combines advantages of both LES and RANS. Generally speaking, mass flow rate prediction is relatively good while swirl/tumble one is more problematic as only qualitative agreement can be achieved.
Nuclear size is sensitive to NTF2 protein levels in a manner dependent on Ran binding
Vuković, Lidija D.; Jevtić, Predrag; Zhang, Zhaojie; Stohr, Bradley A.; Levy, Daniel L.
2016-01-01
ABSTRACT Altered nuclear size is associated with many cancers, and determining whether cancer-associated changes in nuclear size contribute to carcinogenesis necessitates an understanding of mechanisms of nuclear size regulation. Although nuclear import rates generally positively correlate with nuclear size, NTF2 levels negatively affect nuclear size, despite the role of NTF2 (also known as NUTF2) in nuclear recycling of the import factor Ran. We show that binding of Ran to NTF2 is required for NTF2 to inhibit nuclear expansion and import of large cargo molecules in Xenopus laevis egg and embryo extracts, consistent with our observation that NTF2 reduces the diameter of the nuclear pore complex (NPC) in a Ran-binding-dependent manner. Furthermore, we demonstrate that ectopic NTF2 expression in Xenopus embryos and mammalian tissue culture cells alters nuclear size. Finally, we show that increases in nuclear size during melanoma progression correlate with reduced NTF2 expression, and increasing NTF2 levels in melanoma cells is sufficient to reduce nuclear size. These results show a conserved capacity for NTF2 to impact on nuclear size, and we propose that NTF2 might be a new cancer biomarker. PMID:26823604
Nercc1, a mammalian NIMA-family kinase, binds the Ran GTPase and regulates mitotic progression.
Roig, Joan; Mikhailov, Alexei; Belham, Christopher; Avruch, Joseph
2002-07-01
The protein kinase NIMA is an indispensable pleiotropic regulator of mitotic progression in Aspergillus. Although several mammalian NIMA-like kinases (Neks) are known, none appears to have the broad importance for mitotic regulation attributed to NIMA. Nercc1 is a new NIMA-like kinase that regulates chromosome alignment and segregation in mitosis. Its NIMA-like catalytic domain is followed by a noncatalytic tail containing seven repeats homologous to those of the Ran GEF, RCC1, a Ser/Thr/Pro-rich segment, and a coiled-coil domain. Nercc1 binds to another NIMA-like kinase, Nek6, and also binds specifically to the Ran GTPase through both its catalytic and its RCC1-like domains, preferring RanGDP in vivo. Nercc1 exists as a homooligomer and can autoactivate in vitro by autophosphorylation. Nercc1 is a cytoplasmic protein that is activated during mitosis and is avidly phosphorylated by active p34(Cdc2). Microinjection of anti-Nercc1 antibodies in prophase results in spindle abnormalities and/or chromosomal misalignment. In Ptk2 cells the outcome is prometaphase arrest or aberrant chromosome segregation and aneuploidy, whereas in CFPAC-1 cells prolonged arrest in prometaphase is the usual response. Nercc1 and its partner Nek6 represent a new signaling pathway that regulates mitotic progression.
Tabe, Reza; Ghalichi, Farzan; Hossainpour, Siamak; Ghasemzadeh, Kamran
2016-08-12
Laminar, turbulent, transitional, or combine areas of all three types of viscous flow can occur downstream of a stenosis depending upon the Reynolds number and constriction shape parameter. Neither laminar flow solver nor turbulent models for instance the k-ω (k-omega), k-ε (k-epsilon), RANS or LES are opportune for this type of flow. In the present study attention has been focused vigorously on the effect of the constriction in the flow field with a unique way. It means that the laminar solver was employed from entry up to the beginning of the turbulent shear flow. The turbulent model (k-ω SST Transitional Flows) was utilized from starting of turbulence to relaminarization zone while the laminar model was applied again with onset of the relaminarization district. Stenotic flows, with 50 and 75% cross-sectional area, were simulated at Reynolds numbers range from 500 to 2000 employing FLUENT (v6.3.17). The flow was considered to be steady, axisymmetric, and incompressible. Achieving results were reported as axial velocity, disturbance velocity, wall shear stress and the outcomes were compared with previously experimental and CFD computations. The analogy of axial velocity profiles shows that they are in acceptable compliance with the empirical data. As well as disturbance velocity and wall shear stresses anticipated by this new approach, part by part simulation, are reasonably valid with the acceptable experimental studies.
Lagrangian coherent structures in low Reynolds number swimming
Energy Technology Data Exchange (ETDEWEB)
Wilson, Megan M; Eldredge, Jeff D [Mechanical and Aerospace Engineering Department, University of California Los Angeles, Los Angeles, CA 90095 (United States); Peng Jifeng; Dabiri, John O [Department of Bioengineering, California Institute of Technology, Pasadena, CA 91125 (United States)
2009-05-20
This work explores the utility of the finite-time Lyapunov exponent (FTLE) field for revealing flow structures in low Reynolds number biological locomotion. Previous studies of high Reynolds number unsteady flows have demonstrated that ridges of the FTLE field coincide with transport barriers within the flow, which are not shown by a more classical quantity such as vorticity. In low Reynolds number locomotion (O(1)-O(100)), in which viscous diffusion rapidly smears the vorticity in the wake, the FTLE field has the potential to add new insight to locomotion mechanics. The target of study is an articulated two-dimensional model for jellyfish-like locomotion, with swimming Reynolds number of order 1. The self-propulsion of the model is numerically simulated with a viscous vortex particle method, using kinematics adapted from previous experimental measurements on a live medusan swimmer. The roles of the ridges of the computed forward- and backward-time FTLE fields are clarified by tracking clusters of particles both backward and forward in time. It is shown that a series of ridges in front of the jellyfish in the forward-time FTLE field transport slender fingers of fluid toward the lip of the bell orifice, which are pulled once per contraction cycle into the wake of the jellyfish, where the fluid remains partitioned. A strong ridge in the backward-time FTLE field reveals a persistent barrier between fluid inside and outside the subumbrellar cavity. The system is also analyzed in a body-fixed frame subject to a steady free stream, and the FTLE field is used to highlight differences in these frames of reference.
Lagrangian coherent structures in low Reynolds number swimming
Wilson, Megan M.; Peng, Jifeng; Dabiri, John O.; Eldredge, Jeff D.
2009-05-01
This work explores the utility of the finite-time Lyapunov exponent (FTLE) field for revealing flow structures in low Reynolds number biological locomotion. Previous studies of high Reynolds number unsteady flows have demonstrated that ridges of the FTLE field coincide with transport barriers within the flow, which are not shown by a more classical quantity such as vorticity. In low Reynolds number locomotion (O(1)-O(100)), in which viscous diffusion rapidly smears the vorticity in the wake, the FTLE field has the potential to add new insight to locomotion mechanics. The target of study is an articulated two-dimensional model for jellyfish-like locomotion, with swimming Reynolds number of order 1. The self-propulsion of the model is numerically simulated with a viscous vortex particle method, using kinematics adapted from previous experimental measurements on a live medusan swimmer. The roles of the ridges of the computed forward- and backward-time FTLE fields are clarified by tracking clusters of particles both backward and forward in time. It is shown that a series of ridges in front of the jellyfish in the forward-time FTLE field transport slender fingers of fluid toward the lip of the bell orifice, which are pulled once per contraction cycle into the wake of the jellyfish, where the fluid remains partitioned. A strong ridge in the backward-time FTLE field reveals a persistent barrier between fluid inside and outside the subumbrellar cavity. The system is also analyzed in a body-fixed frame subject to a steady free stream, and the FTLE field is used to highlight differences in these frames of reference.
Lagrangian coherent structures in low Reynolds number swimming.
Wilson, Megan M; Peng, Jifeng; Dabiri, John O; Eldredge, Jeff D
2009-05-20
This work explores the utility of the finite-time Lyapunov exponent (FTLE) field for revealing flow structures in low Reynolds number biological locomotion. Previous studies of high Reynolds number unsteady flows have demonstrated that ridges of the FTLE field coincide with transport barriers within the flow, which are not shown by a more classical quantity such as vorticity. In low Reynolds number locomotion (O(1)-O(100)), in which viscous diffusion rapidly smears the vorticity in the wake, the FTLE field has the potential to add new insight to locomotion mechanics. The target of study is an articulated two-dimensional model for jellyfish-like locomotion, with swimming Reynolds number of order 1. The self-propulsion of the model is numerically simulated with a viscous vortex particle method, using kinematics adapted from previous experimental measurements on a live medusan swimmer. The roles of the ridges of the computed forward- and backward-time FTLE fields are clarified by tracking clusters of particles both backward and forward in time. It is shown that a series of ridges in front of the jellyfish in the forward-time FTLE field transport slender fingers of fluid toward the lip of the bell orifice, which are pulled once per contraction cycle into the wake of the jellyfish, where the fluid remains partitioned. A strong ridge in the backward-time FTLE field reveals a persistent barrier between fluid inside and outside the subumbrellar cavity. The system is also analyzed in a body-fixed frame subject to a steady free stream, and the FTLE field is used to highlight differences in these frames of reference.
Dynamics of bubble rising at small Reynolds numbers
Directory of Open Access Journals (Sweden)
Arkhipov Vladimir
2015-01-01
Full Text Available Results of experimental study of a single spherical bubble rising in the non-stationary regime in a viscous liquid (with and without surfactant at small Reynolds numbers Re<1 have been presented. Improved empirical correlations for drag coefficient of the bubble rising with and without surfactant in the stationary regime have been obtained. Influence of nonstationary effects on the dynamics of bubble rising has been analyzed.
Reynolds number and geometry effects in laminar axisymmetric isothermal counterflows
Scribano, Gianfranco
2016-12-29
The counterflow configuration is a canonical stagnation flow, featuring two opposed impinging round jets and a mixing layer across the stagnation plane. Although counterflows are used extensively in the study of reactive mixtures and other applications where mixing of two streams is required, quantitative data on the scaling properties of the flow field are lacking. The aim of this work is to characterize the velocity and mixing fields in isothermal counterflows over a wide range of conditions. The study features both experimental data from particle image velocimetry and results from detailed axisymmetric simulations. The scaling laws for the nondimensional velocity and mixture fraction are obtained as a function of an appropriate Reynolds number and the ratio of the separation distance of the nozzles to their diameter. In the range of flow configurations investigated, the nondimensional fields are found to depend primarily on the separation ratio and, to a lesser extent, the Reynolds number. The marked dependence of the velocity field with respect to the separation ratio is linked to a high pressure region at the stagnation point. On the other hand, Reynolds number effects highlight the role played by the wall boundary layer on the interior of the nozzles, which becomes less important as the separation ratio decreases. The normalized strain rate and scalar dissipation rate at the stagnation plane are found to attain limiting values only for high values of the Reynolds number. These asymptotic values depend markedly on the separation ratio and differ significantly from the values produced by analytical models. The scaling of the mixing field does not show a limiting behavior as the separation ratio decreases to the smallest practical value considered.
History effect on the Reynolds stress in turbulent swirling flow
Hamba, Fujihiro
2017-02-01
The eddy-viscosity model for turbulence has some difficulty in predicting rotating and swirling flows. Turbulent swirling flow in a straight pipe is a typical example. A rapidly rotating core in the pipe decays too quickly in results obtained from the standard k-ɛ model. The eddy viscosity needs to be reduced to predict the velocity profiles well; the mechanism of the decrease in the eddy viscosity has not been clarified yet. In this work, the eddy-viscosity model was investigated using a temporally nonlocal expression for the Reynolds stress that represents the history effect. A simple transport equation for the Reynolds stress was integrated along a mean-flow pathline to obtain a temporally nonlocal model for the Reynolds stress. The nonlocal model was applied to simple swirling flows for which the time integral can be further calculated to investigate the history effect. It was shown that the history effect associated with the rotating motion gives rise to a small factor in the expression for the eddy viscosity. In order to confirm the history effect, the present model and the linear eddy-viscosity model were used to simulate a swirling pipe flow. The velocity profiles obtained from the present model agree well with experimental results; the reduced eddy viscosity can account for the slow decay of the swirling motion in the core region. The anisotropic nature of the eddy viscosity was also discussed in relation to the small factor caused by the history effect.
A Cryogenic High-Reynolds Turbulence Experiment at CERN
Bézaguet, Alain-Arthur; Knoops, S; Lebrun, P; Pezzetti, M; Pirotte, O; Bret, J L; Chabaud, B; Garde, G; Guttin, C; Hébral, B; Pietropinto, S; Roche, P; Barbier-Neyret, J P; Baudet, C; Gagne, Y; Poulain, C; Castaing, B; Ladam, Y; Vittoz, F
2002-01-01
The potential of cryogenic helium flows for studying high-Reynolds number turbulence in the laboratory has been recognised for a long time and implemented in several small-scale hydrodynamic experiments. With its large superconducting particle accelerators and detector magnets, CERN, the European Laboratory for Particle Physics, has become a major world center in helium cryogenics, with several large helium refrigerators having capacities up to 18 kW @ 4.5 K. Combining a small fraction of these resources with the expertise of three laboratories at the forefront of turbulence research, has led to the design, swift implementation, and successful operation of GReC (Grands Reynolds Cryogéniques) a large axisymmetric turbulent-jet experiment. With flow-rates up to 260 g/s of gaseous helium at ~ 5 K and atmospheric pressure, Reynolds numbers up to 107 have been achieved in a 4.6 m high, 1.4 m diameter cryostat. This paper presents the results of the first runs and describes the experimental set-up comprehensively ...
Rotating Convection in F-Planes: Mean Flow and Reynolds Stress
Chan, Kwing L.
2001-02-01
size of the energy flux. (5) We have tabulated the maxima and minima of the mean horizontal velocities, the rms velocities, and correlations between different velocity components for all the cases. Behavioral trends of these quantities can be readily identified. (6) The correlation of the meridional and zonal velocity fluctuations, important in both theory and observation, is found to change its sign from negative to positive when the Rossby number drops past 1. (7) After the meridional momentum equation (which ignores minor effects due to a shell geometry) is averaged over longitude, depth, and time, the resulting equation relates the vertically averaged Reynolds stress to the rotation rate of a whole conical sheet of fluid at a specific latitude. Using our f-plane results to estimate the amount of driving generated by the turbulent Reynolds stress in the solar convection zone, we find that its role is quite insignificant and inadequate for producing the observed differential rotation. We conclude that the latitudinal gas pressure gradient and the global circulation play more important roles.
Large-eddy simulation of atmospheric flow over complex terrain
DEFF Research Database (Denmark)
Bechmann, Andreas
2007-01-01
of the incompressible Reynolds-averaged Navier-Stokes equations (RANS). The k - #epsilon# model is traditionally used for RANS computations, but is here developed to also enable LES. LES is able to provide detailed descriptions of a wide range of engineering flows at low Reynolds numbers. For atmospheric flows, however...
Delgado, Joaquín.; González-García, José S.
2002-08-01
Swimming spherical shapes at low Reynolds number have been used as a model to describe locomotion of several microorganisms such as cyanobacteria. Other examples of biological interest include the motion of vesicles within eucaryotic cells which persists even in the absence of microtubules [Eur. J. Cell. Biol. 60 (1993) 217]. The role of tangential deformation has been pointed out as a reasonable mechanism for self-propulsion of shapes lacking appendages such as cilia or flagella [BMC Microbiol. 1 (1) (2001) 4] and even ranges of wave parameter values have been predicted consistently with its average speed [R. Proc. Natl. Acad. Sci. 93 (1996) 8340] in the case of Synechococcus. Here we re-evaluate the strategy of tangential deformations of a sphere as compared to radial ones in terms of their efficiencies. We confirm under this criterion of optimality that tangential waves are more efficient than radial waves at least within the same range of parameters.
Average Convexity in Communication Situations
Slikker, M.
1998-01-01
In this paper we study inheritance properties of average convexity in communication situations. We show that the underlying graph ensures that the graphrestricted game originating from an average convex game is average convex if and only if every subgraph associated with a component of the
Alternatives to the Moving Average
Paul C. van Deusen
2001-01-01
There are many possible estimators that could be used with annual inventory data. The 5-year moving average has been selected as a default estimator to provide initial results for states having available annual inventory data. User objectives for these estimates are discussed. The characteristics of a moving average are outlined. It is shown that moving average...
National Research Council Canada - National Science Library
Chafe, Shawn C; Pierce, Jacqueline B; Mangroo, Dev
2012-01-01
.... Treatment of mammalian cells with polysorbitan monolaurate was found to inhibit nuclear export of tRNA and proteins, which are processes dependent on RanGTP in the nucleus, but not nuclear import...
Shallow and deep dynamic stall for flapping low Reynolds number airfoils
Energy Technology Data Exchange (ETDEWEB)
Ol, Michael V. [Wright-Patterson AFB, Air Force Research Lab., Dayton, OH (United States); Bernal, Luis; Kang, Chang-Kwon; Shyy, Wei [University of Michigan, Department of Aerospace Engineering, Ann Arbor, MI (United States)
2009-05-15
We consider a combined experimental (based on flow visualization, direct force measurement and phase-averaged 2D particle image velocimetry in a water tunnel), computational (2D Reynolds-averaged Navier-Stokes) and theoretical (Theodorsen's formula) approach to study the fluid physics of rigid-airfoil pitch-plunge in nominally two-dimensional conditions. Shallow-stall (combined pitch-plunge) and deep-stall (pure-plunge) are compared at a reduced frequency commensurate with flapping-flight in cruise in nature. Objectives include assessment of how well attached-flow theory can predict lift coefficient even in the presence of significant separation, and how well 2D velocimetry and 2D computation can mutually validate one another. The shallow-stall case shows promising agreement between computation and experiment, while in the deep-stall case, the computation's prediction of flow separation lags that of the experiment, but eventually evinces qualitatively similar leading edge vortex size. Dye injection was found to give good qualitative match with particle image velocimetry in describing leading edge vortex formation and return to flow reattachment, and also gave evidence of strong spanwise growth of flow separation after leading-edge vortex formation. Reynolds number effects, in the range of 10,000-60,000, were found to influence the size of laminar separation in those phases of motion where instantaneous angle of attack was well below stall, but have limited effect on post-stall flowfield behavior. Discrepancy in lift coefficient time history between experiment, theory and computation was mutually comparable, with no clear failure of Theodorsen's formula. This is surprising and encouraging, especially for the deep-stall case, because the theory's assumptions are clearly violated, while its prediction of lift coefficient remains useful for capturing general trends. (orig.)
Directory of Open Access Journals (Sweden)
S. M. Yadav
2011-02-01
Full Text Available The computation of bed load allows for the fact that only part of the shear stress is used for transport of sediments and some of the shear stress is wasted in overcoming the resistance due to bed forms therefore the total shear stress developed in the open channel requires correction in the form of correction factor called ripple factor. Different methods have been followed for correcting the actual shear stress in order to compute the sediment load. Correction factors are based on particular characteristics grain size of particle. In the present paper the ripple factor has been obtained for non uniform bed material considering the various variables like discharge, hydraulic mean depth, flow velocity, bed slope, average diameter of particle etc. by collecting the field data of Tapi river for 15 years for a particular gauging station. The ripple factor is obtained using Meyer Peter and Muller formula, Einstein Formula, Kalinske’s formula, Du Boy’s formula, Shield’s formula, Bagnold’s formula, average of six formulae and multiple regression analysis. The variation of ripple factor with particle Reynolds Number is studied. The ripple factor obtained by different approaches are further analyzed using Origin software and carrying out multiple regression on the 15 years of data with more than 10 parameters, ripple factor by multiple regression has been obtained. These values are further analysed and giving statistical mean to the parameters a relationship of power form has been developed. The ripple factor increases with the increase in the value of Particle Reynolds number. The large deviation is observed in case of Kalinske’s approach when compare with other approaches
The difference between alternative averages
Directory of Open Access Journals (Sweden)
James Vaupel
2012-09-01
Full Text Available BACKGROUND Demographers have long been interested in how compositional change, e.g., change in age structure, affects population averages. OBJECTIVE We want to deepen understanding of how compositional change affects population averages. RESULTS The difference between two averages of a variable, calculated using alternative weighting functions, equals the covariance between the variable and the ratio of the weighting functions, divided by the average of the ratio. We compare weighted and unweighted averages and also provide examples of use of the relationship in analyses of fertility and mortality. COMMENTS Other uses of covariances in formal demography are worth exploring.
Hilbi, Hubert; Rothmeier, Eva; Hoffmann, Christine; Harrison, Christopher F
2014-01-01
Legionella spp. are amoebae-resistant environmental bacteria that replicate in free-living protozoa in a distinct compartment, the Legionella-containing vacuole (LCV). Upon transmission of Legionella pneumophila to the lung, the pathogens employ an evolutionarily conserved mechanism to grow in LCVs within alveolar macrophages, thus triggering a severe pneumonia termed Legionnaires' disease. LCV formation is a complex and robust process, which requires the bacterial Icm/Dot type IV secretion system and involves the amazing number of 300 different translocated effector proteins. LCVs interact with the host cell's endosomal and secretory vesicle trafficking pathway. Accordingly, in a proteomics approach as many as 12 small Rab GTPases implicated in endosomal and secretory vesicle trafficking were identified and validated as LCV components. Moreover, the small GTPase Ran and its effector protein RanBP1 have been found to decorate the pathogen vacuole. Ran regulates nucleo-cytoplasmic transport, spindle assembly, and cytokinesis, as well as the organization of non-centrosomal microtubules. In L. pneumophila-infected amoebae or macrophages, Ran and RanBP1 localize to LCVs, and the small GTPase is activated by the Icm/Dot substrate LegG1. Ran activation by LegG1 leads to microtubule stabilization and promotes intracellular pathogen vacuole motility and bacterial growth, as well as chemotaxis and migration of Legionella-infected cells.
Yokoyama, Hideki; Koch, Birgit; Walczak, Rudolf; Ciray-Duygu, Fulya; González-Sánchez, Juan Carlos; Devos, Damien P; Mattaj, Iain W; Gruss, Oliver J
2014-01-01
The GTP-bound form of the Ran GTPase (RanGTP), produced around chromosomes, drives nuclear envelope and nuclear pore complex (NPC) re-assembly after mitosis. The nucleoporin MEL-28/ELYS binds chromatin in a RanGTP-regulated manner and acts to seed NPC assembly. Here we show that, upon mitotic NPC disassembly, MEL-28 dissociates from chromatin and re-localizes to spindle microtubules and kinetochores. MEL-28 directly binds microtubules in a RanGTP-regulated way via its C-terminal chromatin-binding domain. Using Xenopus egg extracts, we demonstrate that MEL-28 is essential for RanGTP-dependent microtubule nucleation and spindle assembly, independent of its function in NPC assembly. Specifically, MEL-28 interacts with the γ-tubulin ring complex and recruits it to microtubule nucleation sites. Our data identify MEL-28 as a RanGTP target that functions throughout the cell cycle. Its cell cycle-dependent binding to chromatin or microtubules discriminates MEL-28 functions in interphase and mitosis, and ensures that spindle assembly occurs only after NPC breakdown.
Dombrowski, Stefan C.; Mrazik, Martin
2008-01-01
In this article, the authors review the Reynolds Intellectual Assessment Scales (RIAS; Reynolds & Kamphaus, 2003), an individually administered test of intelligence for use with individuals between the ages of 3 and 94. The RIAS represents the newest intelligence test on the marketplace and incorporates the most current intelligence test theory…
Challenges in simulating coastal effects on an offshore wind farm
van der Laan, M. P.; Peña, A.; Volker, P.; Hansen, K. S.; Sørensen, N. N.; Ott, S.; Hasager, C. B.
2017-05-01
The effect of a coastline on an offshore wind farm is investigated with a Reynolds-averaged Navier-Stokes (RANS) model. The trends of the RANS model compare relatively well with results from a mesoscale model and measurements of wind turbine power. In addition, challenges of modeling a large domain in RANS are discussed.
Ivan Rančić: A forgotten painter of flowers and landscapes
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Marković Kamenko M.
2014-01-01
Full Text Available Ivan Rančić was born in the Kraljevo village, in eastern Serbia to a family of farmers on 19th, February, 1906. Very little data about him has been preserved, therefore, this paper is an attempt to make a reconstruction of his life and work. He attended primary school in his birth place, lower secondary school he finished in Knjazevac and Military Academy in Belgrade. After completing the National Academy in 1934, he was sent to Zagreb where he got his first post. He lived there with his wife and his son until the capitulation of the country in 1941. A few months after the collapse of the country, he was arrested and sent to Ljubljana and three months later to a concentration camp in Austria. He spent about fifteen months in that camp in during which time he intensively studied painting. He fled from the camp to Switzerland and stayed there until his death in 1987. According to some letters he sent to his wife in Nis, some of his paintings he created during his time in the camp, ne took to Switzerland where he eventually sold them. He did the toughest jobs there in order to survive and painted extensively. After World War II he graduated from the School of Fine Arts in Lausanne. Later on he had two exhibitions at the New Gallery of Modern Art. Ivan Rančić came a long way from an unknown beginner to a respected prominent artist. He left behind about 350 works, many of which he sold during his life, mainly landscapes and still life in oil, watercolor and pastel. He was neither concerned about styles and trends nor did he believe in the old and the new. If he came to a certain specific manner of painting, it is because at one point it was imposed on him as the only proper way of expression. The analysis of Rančić's paintings leads to the conclusion that his creation had gone through four phases. The first one (started in the concentration camp in Austria during which he painted still lifes without full sketches, previous studies, and the use
Directory of Open Access Journals (Sweden)
Özgür ÜŞENMEZ
2015-07-01
Full Text Available ÖZ: Bu çalışma, İran rejiminin son yıllarda Orta Doğu'yu sarsan isyanlar ve istikrarsızlıklara-Batı'daki beklentilerin aksine- geçmişten, özellikle 1979'daki devrimden miras kalan sosyal yapı ve politikaların etkisiyle direnebildiğini iddia ediyor. Tunus ve Mısır'daki halk isyanları, temel aktör olan alt sınıflar ve onların neo-liberal ekonomik politikalara muhalefetiyle yayılırken, İran’da devrim sonrası gelişen sosyal devlet mekanizması hala halk ile rejimin tamamen birbirine yabancılaşmasını önlemekte. Ancak son yıllarda ortaya çıkan yeni gerilimler ve İran'ın uyguladığı ekonomi politikaları rejimin krizini derinleştirebilir. Bu nedenledir ki Orta Doğu'yu ve özelde İran'ı anlamak için hegemonik blokların tarihsel değişimini inceleyen ucu açık bir analiz elzemdir. ABSTRACT: This article argues that contrary to the expectations of the Western World, Iranian regime successfully resisted the revolutionary tides of the Arab Spring. Most important determinant of this process for Iran was the legacy of the 1979 revolution and it's associated structures that relatively protects the most vulnerable parts of the population against the wide spread neo-liberal economic policies in the Middle East. So with that feature Iran differs from the Tunisian and the Egyptian examples. In order to understand these features further this essay adapts a historical analysis of changes in hegemonic blocs in Iran since 1979.
Optimal translational swimming of a sphere at low Reynolds number
Felderhof, B U
2015-01-01
Swimming velocity and rate of dissipation of a sphere with surface distortions are discussed on the basis of the Stokes equations of low Reynolds number hydrodynamics. At first the surface distortions are assumed to cause an irrotational axisymmetric flow pattern. The efficiency of swimming is optimized within this class of flows. Subsequently more general axisymmetric polar flows with vorticity are considered. This leads to a considerably higher maximum efficiency. An additional measure of swimming performance is proposed based on the energy consumption for given amplitude of stroke.
Resonance of flexible flapping wings at low Reynolds number.
Masoud, Hassan; Alexeev, Alexander
2010-05-01
Using three-dimensional computer simulations, we examine hovering aerodynamics of flexible planar wings oscillating at resonance. We model flexible wings as tilted elastic plates whose sinusoidal plunging motion is imposed at the plate root. Our simulations reveal that large-amplitude resonance oscillations of elastic wings drastically enhance aerodynamic lift and efficiency of low-Reynolds-number plunging. Driven by a simple sinusoidal stroke, flexible wings at resonance generate a hovering force comparable to that of small insects that employ a very efficient but much more complicated stroke kinematics. Our results indicate the feasibility of using flexible wings driven by a simple harmonic stroke for designing efficient microscale flying machines.
Vortex Shedding from Tapered Cylinders at high Reynolds Numbers
DEFF Research Database (Denmark)
Johansson, Jens; Andersen, Michael Styrk; Christensen, Silas Sverre
2015-01-01
: Helical strakes are known to reduce or suppress vortex-induced vibrations (VIV) of circular structures. The design of the strakes is generally recommended to be a triple-start helical strake system, with a strake height corresponding to approximately 10 percent of the structures diameter and 15...... percent for strakes of circular cross section. The present paper argues that this height can be reduced for structures where the critical wind velocity for vortex shedding is in the Supercritical Reynolds number regime. The present investigations are aimed for suppressing VIV on offshore wind turbine...
Rigorous justification of the Reynolds equations for gas lubrication
Marušić-Paloka, Eduard; Starčević, Maja
2005-07-01
The goal of this Note is to give a rigorous justification of the compressible Reynolds model for gas lubrication, via asymptotic analysis. We start from the equations of motion of compressible viscous fluid in a thin domain and study the limit as the domain thickness tends to zero. At the limit we find the known engineering model. The key of the proof is the strong convergence for the pressure obtained by its decomposition. To cite this article: E. Marušić-Paloka, M. Starčević, C. R. Mecanique 333 (2005).
DEFF Research Database (Denmark)
Checko, Aleksandra; Kardaras, Georgios; Lanzani, Christian Fabio Alessandro
This white paper presents a proof of concept implementation of digital baseband radio data transport over Optical Transport Network (OTN) compliant to 3GPP Long Term Evolution – Advanced (LTE-A) standard enabling Cloud Radio Access Network (C-RAN) architecture. The transport between the baseband...... module and a remote radio module is compliant to Common Public Radio Interface (CPRI) and to the OBSAI reference point 3 - 01 (RP3-01) interface protocols, respectively. The purpose is to demonstrate that data integrity and clocking performance at the radio node still meets the strict standard...
Statistical Multiplexing of Computations in C-RAN with Tradeoffs in Latency and Energy
DEFF Research Database (Denmark)
Kalør, Anders Ellersgaard; Agurto Agurto, Mauricio Ignacio; Pratas, Nuno
2017-01-01
In the Cloud Radio Access Network (C-RAN) architecture, the baseband signals from multiple remote radio heads are processed in a centralized baseband unit (BBU) pool. This architecture allows network operators to adapt the BBU’s computational resources to the aggregate access load experienced...... frame duration, then this may result in additional access latency and limit the energy savings. In this paper we investigate the tradeoff by considering two extreme time-scales for the resource multiplexing: (i) long-term, where the computational resources are adapted over periods much larger than...
Synchronization challenges in packet-based Cloud-RAN fronthaul for mobile networks
DEFF Research Database (Denmark)
Checko, Aleksandra; Juul, Anders Christian; Christiansen, Henrik Lehrmann
2015-01-01
In this paper, we look at reusing existing packet-based network (e.g. Ethernet) to possibly decrease deployment costs of fronthaul Cloud Radio Access Network (C-RAN) network and cost of Baseband Unit (BBU) resources. The challenge of this solution is that it requires mobile traffic (until now...... transmitted over synchronous protocols) to traverse the asynchronous Ethernet without losing synchronization. We analyze synchronization requirements of mobile networks and present an overview of solutions that fulfill them in traditional mobile networks. Then we elaborate on challenges that packet...... bridge the gap between Ethernet and mobile network domains creating a comprehensive architectural analysis....
Accelerating Universe via Spatial Averaging
Nambu, Yasusada; TANIMOTO, Masayuki
2005-01-01
We present a model of an inhomogeneous universe that leads to accelerated expansion after taking spatial averaging. The model universe is the Tolman-Bondi solution of the Einstein equation and contains both a region with positive spatial curvature and a region with negative spatial curvature. We find that after the region with positive spatial curvature begins to re-collapse, the deceleration parameter of the spatially averaged universe becomes negative and the averaged universe starts accele...
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Kai-Long Li
Full Text Available Ran (RanGTPase in insects participates in the 20-hydroxyecdysone signal transduction pathway in which downstream genes, FTZ-F1, Krüppel-homolog 1 (Kr-h1 and vitellogenin, are involved. A putative Ran gene (NlRan was cloned from Nilaparvata lugens, a destructive phloem-feeding pest of rice. NlRan has the typical Ran primary structure features that are conserved in insects. NlRan showed higher mRNA abundance immediately after molting and peaked in newly emerged female adults. Among the examined tissues ovary had the highest transcript level, followed by fat body, midgut and integument, and legs. Three days after dsNlRan injection the NlRan mRNA abundance in the third-, fourth-, and fifth-instar nymphs was decreased by 94.3%, 98.4% and 97.0%, respectively. NlFTZ-F1 expression levels in treated third- and fourth-instar nymphs were reduced by 89.3% and 23.8%, respectively. In contrast, NlKr-h1 mRNA levels were up-regulated by 67.5 and 1.5 folds, respectively. NlRan knockdown significantly decreased the body weights, delayed development, and killed >85% of the nymphs at day seven. Two apparent phenotypic defects were observed: (1 Extended body form, and failed to molt; (2 The cuticle at the notum was split open but cannot completely shed off. The newly emerged female adults from dsNlRan injected fifth-instar nymphs showed lower levels of NlRan and vitellogenin, lower weight gain and honeydew excretion comparing with the blank control, and no offspring. Those results suggest that NlRan encodes a functional protein that was involved in development and reproduction. The study established proof of concept that NlRan could serve as a target for dsRNA-based pesticides for N. lugens control.
Evaluation of Algebraic Reynolds Stress Model Assumptions Using Experimental Data
Jyoti, B.; Ewing, D.; Matovic, D.
1996-11-01
The accuracy of Rodi's ASM assumption is examined by evaluating the terms in Reynolds stress transport equation and their modelled counterparts. The basic model assumption: Dτ_ij/Dt + partial T_ijl/partial xl = (τ_ij/k )(Dk/Dt + partial Tl /partial xl ) (Rodi( Rodi W., ZAMM.), 56, pp. 219-221, 1976.), can also be broken into two stronger assumptions: Da_ij/Dt = 0 and (2) partial T_ijl/partial xl = (τ_ij/k )(partial Tl /partial xl ) (e.g. Taulbee( Taulbee D. B., Phys. of Fluids), 4(11), pp. 2555-2561, 1992.). Fu et al( Fu S., Huang P.G., Launder B.E. & Leschziner M.A., J. Fluid Eng.), 110(2), pp. 216-221., 1988 examined the accuracy of Rodi's assumption using the results of RSM calculation of axisymmetric jets. Since the RSM results did not accurately predict the experimental results either, it may be useful to examine the basic ASM model assumptions using experimental data. The database of Hussein, Capp and George( Hussein H., Capp S. & George W., J.F.M.), 258, pp.31-75., 1994. is sufficiently detailed to evaluate the terms of Reynolds stress transport equations individually, thus allowing both Rodi's and the stronger assumptions to be tested. For this flow assumption (1) is well satisfied for all the components (including \\overlineuv); however, assumption (2) does not seem as well satisfied.
Low Reynolds Number Wing Transients in Rotation and Translation
Jones, Anya; Schlueter, Kristy
2012-11-01
The unsteady aerodynamic forces and flow fields generated by a wing undergoing transient motions in both rotation and translation were investigated. An aspect ratio 2 flat plate wing at a 45 deg angle of attack was driven over 84 deg of rotation (3 chord-lengths of travel at 3/4 span) and 3 and 10 chord-lengths of translation in quiescent water at Reynolds numbers between 2,500 and 15,000. Flow visualization on the rotating wing revealed a leading edge vortex that lifted off of the wing surface, but remained in the vicinity of the wing for the duration of the wing stroke. A second spanwise vortex with strong axial flow was also observed. As the tip vortex grew, the leading edge vortex joined the tip vortex in a loop-like structure over the aft half of the wing. Near the leading edge, spanwise flow in the second vortex became entrained in the tip vortex near the corner of the wing. Unsteady force measurements revealed that lift coefficient increased through the constant-velocity portion of the wing stroke. Forces were compared for variations in wing acceleration and Reynolds number for both rotational and translational motions. The effect of tank blockage was investigated by repeating the experiments on multiple wings, varying the distance between the wing tip and tank wall. U.S. Air Force Research Laboratory, Summer Faculty Fellowship Program.
Unsteady aerodynamic models for agile flight at low Reynolds numbers
Brunton, Steven L.
This work develops low-order models for the unsteady aerodynamic forces on a wing in response to agile maneuvers at low Reynolds number. Model performance is assessed on the basis of accuracy across a range of parameters and frequencies as well as of computational efficiency and compatibility with existing control techniques and flight dynamic models. The result is a flexible modeling procedure that yields accurate, low-dimensional, state-space models. The modeling procedures are developed and tested on direct numerical simulations of a two-dimensional flat plate airfoil in motion at low Reynolds number, Re=100, and in a wind tunnel experiment at the Illinois Institute of Technology involving a NACA 0006 airfoil pitching and plunging at Reynolds number Re=65,000. In both instances, low-order models are obtained that accurately capture the unsteady aerodynamic forces at all frequencies. These cases demonstrate the utility of the modeling procedure developed in this thesis for obtaining accurate models for different geometries and Reynolds numbers. Linear reduced-order models are constructed from either the indicial response (step response) or realistic input/output maneuvers using a flexible modeling procedure. The method is based on identifying stability derivatives and modeling the remaining dynamics with the eigensystem realization algorithm. A hierarchy of models is developed, based on linearizing the flow at various operating conditions. These models are shown to be accurate and efficient for plunging, pitching about various points, and combined pitch and plunge maneuvers, at various angle of attack and Reynolds number. Models are compared against the classical unsteady aerodynamic models of Wagner and Theodorsen over a large range of Strouhal number and reduced frequency for a baseline comparison. Additionally, state-space representations are developed for Wagner's and Theodorsen's models, making them compatible with modern control-system analysis. A number of
Canoe binds RanGTP to promote PinsTPR/Mud-mediated spindle orientation
Wee, Brett; Johnston, Christopher A.
2011-01-01
Regulated spindle orientation maintains epithelial tissue integrity and stem cell asymmetric cell division. In Drosophila melanogaster neural stem cells (neuroblasts), the scaffolding protein Canoe (Afadin/Af-6 in mammals) regulates spindle orientation, but its protein interaction partners and mechanism of action are unknown. In this paper, we use our recently developed induced cell polarity system to dissect the molecular mechanism of Canoe-mediated spindle orientation. We show that a previously uncharacterized portion of Canoe directly binds the Partner of Inscuteable (Pins) tetratricopeptide repeat (TPR) domain. The Canoe–PinsTPR interaction recruits Canoe to the cell cortex and is required for activation of the PinsTPR-Mud (nuclear mitotic apparatus in mammals) spindle orientation pathway. We show that the Canoe Ras-association (RA) domains directly bind RanGTP and that both the CanoeRA domains and RanGTP are required to recruit Mud to the cortex and activate the Pins/Mud/dynein spindle orientation pathway. PMID:22024168
Validation of Heat Transfer and Film Cooling Capabilities of the 3-D RANS Code TURBO
Shyam, Vikram; Ameri, Ali; Chen, Jen-Ping
2010-01-01
The capabilities of the 3-D unsteady RANS code TURBO have been extended to include heat transfer and film cooling applications. The results of simulations performed with the modified code are compared to experiment and to theory, where applicable. Wilcox s k-turbulence model has been implemented to close the RANS equations. Two simulations are conducted: (1) flow over a flat plate and (2) flow over an adiabatic flat plate cooled by one hole inclined at 35 to the free stream. For (1) agreement with theory is found to be excellent for heat transfer, represented by local Nusselt number, and quite good for momentum, as represented by the local skin friction coefficient. This report compares the local skin friction coefficients and Nusselt numbers on a flat plate obtained using Wilcox's k-model with the theory of Blasius. The study looks at laminar and turbulent flows over an adiabatic flat plate and over an isothermal flat plate for two different wall temperatures. It is shown that TURBO is able to accurately predict heat transfer on a flat plate. For (2) TURBO shows good qualitative agreement with film cooling experiments performed on a flat plate with one cooling hole. Quantitatively, film effectiveness is under predicted downstream of the hole.
Reynolds number limits for jet propulsion: a numerical study of simplified jellyfish.
Herschlag, Gregory; Miller, Laura
2011-09-21
The Scallop theorem states that reciprocal methods of locomotion, such as jet propulsion or paddling, will not work in Stokes flow (Reynolds number=0). In nature the effective limit of jet propulsion is still in the range where inertial forces are significant. It appears that almost all animals that use jet propulsion swim at Reynolds numbers (Re) of about 5 or more. Juvenile squid and octopods hatch from the egg already swimming in this inertial regime. Juvenile jellyfish, or ephyrae, break off from polyps swimming at Re greater than 5. Many other organisms, such as scallops, rarely swim at Re less than 100. The limitations of jet propulsion at intermediate Re is explored here using the immersed boundary method to solve the 2D Navier-Stokes equations coupled to the motion of a simplified jellyfish. The contraction and expansion kinematics are prescribed, but the forward and backward swimming motions of the idealized jellyfish are emergent properties determined by the resulting fluid dynamics. Simulations are performed for both an oblate bell shape using a paddling mode of swimming and a prolate bell shape using jet propulsion. Average forward velocities and work put into the system are calculated for Re between 1 and 320. The results show that forward velocities rapidly decay with decreasing Re for all bell shapes when Reswimming velocities and vortex separation patterns for the model prolate agree with those observed in Nemopsis bachei. The forward swimming velocities of the model oblate jellyfish after two pulse cycles are comparable to those reported for Aurelia aurita, but discrepancies are observed in the vortex dynamics between when the 2D model oblate jellyfish and the organism. This discrepancy is likely due to a combination of the differences between the 3D reality of the jellyfish and the 2D simplification, as well as the rigidity of the time varying geometry imposed by the idealized model. Copyright © 2011 Elsevier Ltd. All rights reserved.
Saturated flow in a single fracture: Evaluation of the Reynolds equation in measured aperture fields
Energy Technology Data Exchange (ETDEWEB)
NICHOLL,M.J.; RAJARAM,H.; GLASS JR.,ROBERT J.; DETWILER,R.
2000-01-28
Fracture transmissivity and detailed aperture fields are measured in analog fractures specially designed to evaluate the utility of the Reynolds equation. The authors employ a light transmission technique with well-defined accuracy ({approximately}1% error) to measure aperture fields at high spatial resolution ({approximately}0.015 cm). A Hele-Shaw cell is used to confirm the approach by demonstrating agreement between experimental transmissivity, simulated transmissivity on the measured aperture field, and the parallel plate law. In the two rough-walled analog fractures considered, the discrepancy between the experimental and numerical estimates of fracture transmissivity was sufficiently large ({approximately} 22--47%) to exclude numerical and experimental errors (< 2%)as a source. They conclude that the three-dimensional character of the flow field is important for fully describing fluid flow in the two rough-walled fractures considered, and that the approach of depth averaging inherent in the formulation of the Reynolds equation is inadequate. They also explore the effects of spatial resolution, aperture measurement technique, and alternative definitions for link transmissivities in the finite-difference formulation, including some that contain corrections for tortuosity perpendicular to the mean fracture plane and Stokes flow. Various formulations for link transmissivity are shown to converge at high resolution ({approximately} 1/5 the spatial correlation length) in the smoothly varying fracture. At coarser resolutions, the solution becomes increasingly sensitive to definition of link transmissivity and measurement technique. Aperture measurements that integrate over individual grid blocks were less sensitive to measurement scale and definition of link transmissivity than point sampling techniques.
Ensemble Averaged Probability Density Function (APDF) for Compressible Turbulent Reacting Flows
Shih, Tsan-Hsing; Liu, Nan-Suey
2012-01-01
In this paper, we present a concept of the averaged probability density function (APDF) for studying compressible turbulent reacting flows. The APDF is defined as an ensemble average of the fine grained probability density function (FG-PDF) with a mass density weighting. It can be used to exactly deduce the mass density weighted, ensemble averaged turbulent mean variables. The transport equation for APDF can be derived in two ways. One is the traditional way that starts from the transport equation of FG-PDF, in which the compressible Navier- Stokes equations are embedded. The resulting transport equation of APDF is then in a traditional form that contains conditional means of all terms from the right hand side of the Navier-Stokes equations except for the chemical reaction term. These conditional means are new unknown quantities that need to be modeled. Another way of deriving the transport equation of APDF is to start directly from the ensemble averaged Navier-Stokes equations. The resulting transport equation of APDF derived from this approach appears in a closed form without any need for additional modeling. The methodology of ensemble averaging presented in this paper can be extended to other averaging procedures: for example, the Reynolds time averaging for statistically steady flow and the Reynolds spatial averaging for statistically homogeneous flow. It can also be extended to a time or spatial filtering procedure to construct the filtered density function (FDF) for the large eddy simulation (LES) of compressible turbulent reacting flows.
Irrecoverable pressure loss coefficients for two out-of-plane piping elbows at high Reynolds number
Energy Technology Data Exchange (ETDEWEB)
Coffield, R.D.; Hammond, R.B.; McKeown, P.T.
1999-02-08
Pressure drops of multiple piping elbows were experimentally determined for high Reynolds number flows. The testing described has been performed in order to reduce uncertainties in the currently used methods for predicting irrecoverable pressure losses and also to provide a qualification database for computational fluid dynamics (CFD) computer codes. The earlier high Reynolds number correlations had been based on extrapolations over several orders of magnitude in Reynolds number from where the original database existed. Recent single elbow test data shows about a factor of two lower elbow pressure loss coefficient (at 40x 106 Reynolds number) than those from current correlations. This single piping elbow data has been extended in this study to a multiple elbow configuration of two elbows that are 90o out-of-plane relative to each other. The effects of separation distance and Reynolds number have been correlated and presented in a form that can be used for design application. Contrary to earlier extrapolations from low Reynolds numbers (Re c 1.0x 106), a strong Reynolds number dependence was found to exist. The combination of the high Reynolds number single elbow data with the multiple elbow interaction effects measured in this study shows that earlier design correlations are conservative by significant margins at high Reynolds numbers. Qualification of CFD predictions with this new high Reynolds number database will help guide the need for additional high Reynolds number testing of other piping configurations. The study also included velocity measurements at several positions downstream of the first and second test elbows using an ultrasonic flowmeter. Reasonable agreement after the first test elbow was found relative to flow fields that are known to exist from low Reynolds number visual tests and also from CFD predictions. This data should help to qualify CFD predictions of the three-dimensional flow stream downstream of the second test elbow.
Ran GTPase-activating protein 1 is a therapeutic target in diffuse large B-cell lymphoma.
Directory of Open Access Journals (Sweden)
Kung-Chao Chang
Full Text Available Lymphoma-specific biomarkers contribute to therapeutic strategies and the study of tumorigenesis. Diffuse large B-cell lymphoma (DLBCL is the most common type of malignant lymphoma. However, only 50% of patients experience long-term survival after current treatment; therefore, developing novel therapeutic strategies is warranted. Comparative proteomic analysis of two DLBCL lines with a B-lymphoblastoid cell line (LCL showed differential expression of Ran GTPase-activating protein 1 (RanGAP1 between them, which was confirmed using immunoblotting. Immunostaining showed that the majority of DLBCLs (92%, 46/50 were RanGAP1(+, while reactive lymphoid hyperplasia (n = 12 was RanGAP1(+ predominantly in germinal centers. RanGAP1 was also highly expressed in other B-cell lymphomas (BCL, n = 180 with brisk mitotic activity (B-lymphoblastic lymphoma/leukemia: 93%, and Burkitt lymphoma: 95% or cell-cycle dysregulation (mantle cell lymphoma: 83%, and Hodgkin's lymphoma 91%. Interestingly, serum RanGAP1 level was higher in patients with high-grade BCL (1.71 ± 2.28 ng/mL, n = 62 than in low-grade BCL (0.75 ± 2.12 ng/mL, n = 52 and healthy controls (0.55 ± 1.58 ng/mL, n = 75 (high-grade BCL vs. low-grade BCL, p = 0.002; high-grade BCL vs. control, p < 0.001, Mann-Whitney U test. In vitro, RNA interference of RanGAP1 showed no effect on LCL but enhanced DLBCL cell death (41% vs. 60%; p = 0.035 and cell-cycle arrest (G0/G1: 39% vs. 49%, G2/M: 19.0% vs. 7.5%; p = 0.030 along with decreased expression of TPX2 and Aurora kinases, the central regulators of mitotic cell division. Furthermore, ON 01910.Na (Estybon, a multikinase inhibitor induced cell death, mitotic cell arrest, and hyperphosphorylation of RanGAP1 in DLBCL cell lines but no effects in normal B and T cells. Therefore, RanGAP1 is a promising marker and therapeutic target for aggressive B-cell lymphoma, especially DLBCL.
Broeren, Andy P.; Woodard, Brian S.; Diebold, Jeffrey M.; Moens, Frederic
2017-01-01
Aerodynamic assessment of icing effects on swept wings is an important component of a larger effort to improve three-dimensional icing simulation capabilities. An understanding of ice-shape geometric fidelity and Reynolds and Mach number effects on the iced-wing aerodynamics is needed to guide the development and validation of ice-accretion simulation tools. To this end, wind-tunnel testing and computational flow simulations were carried out for an 8.9 percent-scale semispan wing based upon the Common Research Model airplane configuration. The wind-tunnel testing was conducted at the Wichita State University 7 by 10 ft Beech wind tunnel from Reynolds numbers of 0.8×10(exp 6) to 2.4×10(exp 6) and corresponding Mach numbers of 0.09 to 0.27. This paper presents the results of initial studies investigating the model mounting configuration, clean-wing aerodynamics and effects of artificial ice roughness. Four different model mounting configurations were considered and a circular splitter plate combined with a streamlined shroud was selected as the baseline geometry for the remainder of the experiments and computational simulations. A detailed study of the clean-wing aerodynamics and stall characteristics was made. In all cases, the flow over the outboard sections of the wing separated as the wing stalled with the inboard sections near the root maintaining attached flow. Computational flow simulations were carried out with the ONERA elsA software that solves the compressible, threedimensional RANS equations. The computations were carried out in either fully turbulent mode or with natural transition. Better agreement between the experimental and computational results was obtained when considering computations with free transition compared to turbulent solutions. These results indicate that experimental evolution of the clean wing performance coefficients were due to the effect of three-dimensional transition location and that this must be taken into account for future
High average power supercontinuum sources
Indian Academy of Sciences (India)
.uk. Abstract. The physical mechanisms and basic experimental techniques for the creation of high average spectral power supercontinuum sources is briefly reviewed. We focus on the use of high-power ytterbium-doped fibre lasers as pump ...
Directory of Open Access Journals (Sweden)
Shawn C Chafe
Full Text Available NTF2 is a cytosolic protein responsible for nuclear import of Ran, a small Ras-like GTPase involved in a number of critical cellular processes, including cell cycle regulation, chromatin organization during mitosis, reformation of the nuclear envelope following mitosis, and controlling the directionality of nucleocytoplasmic transport. Herein, we provide evidence for the first time that translocation of the mammalian NTF2 from the nucleus to the cytoplasm to collect Ran in the GDP form is subjected to regulation. Treatment of mammalian cells with polysorbitan monolaurate was found to inhibit nuclear export of tRNA and proteins, which are processes dependent on RanGTP in the nucleus, but not nuclear import of proteins. Inhibition of the export processes by polysorbitan monolaurate is specific and reversible, and is caused by accumulation of Ran in the cytoplasm because of a block in translocation of NTF2 to the cytoplasm. Nuclear import of Ran and the nuclear export processes are restored in polysorbitan monolaurate treated cells overproducing NTF2. Moreover, increased phosphorylation of a phospho-tyrosine protein and several phospho-threonine proteins was observed in polysorbitan monolaurate treated cells. Collectively, these findings suggest that nucleocytoplasmic translocation of NTF2 is regulated in mammalian cells, and may involve a tyrosine and/or threonine kinase-dependent signal transduction mechanism(s.
From averaged to simultaneous controllability
Lohéac, Jérôme; Zuazua, Enrique
2016-01-01
International audience; We consider a linear finite dimensional control system depending on unknown parameters. We aim to design controls, independent of the parameters, to control the system in some optimal sense. We discuss the notions of averaged control, according to which one aims to control only the average of the states with respect to the unknown parameters, and the notion of simultaneous control in which the goal is to control the system for all values of these parameters. We show ho...
Mixture Model Averaging for Clustering
Wei, Yuhong; McNicholas, Paul D.
2012-01-01
In mixture model-based clustering applications, it is common to fit several models from a family and report clustering results from only the `best' one. In such circumstances, selection of this best model is achieved using a model selection criterion, most often the Bayesian information criterion. Rather than throw away all but the best model, we average multiple models that are in some sense close to the best one, thereby producing a weighted average of clustering results. Two (weighted) ave...
Convergence of multiple ergodic averages
Host, Bernard
2006-01-01
These notes are based on a course for a general audience given at the Centro de Modeliamento Matem\\'atico of the University of Chile, in December 2004. We study the mean convergence of multiple ergodic averages, that is, averages of a product of functions taken at different times. We also describe the relations between this area of ergodic theory and some classical and some recent results in additive number theory.
Average inbreeding or equilibrium inbreeding?
Hedrick, P. W.
1986-01-01
The equilibrium inbreeding is always higher than the average inbreeding. For human populations with high inbreeding levels, the inbreeding equilibrium is more than 25% higher than the average inbreeding. Assuming no initial inbreeding in the population, the equilibrium inbreeding value is closely approached in 10 generations or less. A secondary effect of this higher inbreeding level is that the equilibrium frequency of recessive detrimental alleles is somewhat lower than expected using avera...
Directory of Open Access Journals (Sweden)
Peter Bachant
2016-01-01
Full Text Available Experiments were performed with a large laboratory-scale high solidity cross-flow turbine to investigate Reynolds number effects on performance and wake characteristics and to establish scale thresholds for physical and numerical modeling of individual devices and arrays. It was demonstrated that the performance of the cross-flow turbine becomes essentially R e -independent at a Reynolds number based on the rotor diameter R e D ≈ 10 6 or an approximate average Reynolds number based on the blade chord length R e c ≈ 2 × 10 5 . A simple model that calculates the peak torque coefficient from static foil data and cross-flow turbine kinematics was shown to be a reasonable predictor for Reynolds number dependence of an actual cross-flow turbine operating under dynamic conditions. Mean velocity and turbulence measurements in the near-wake showed subtle differences over the range of R e investigated. However, when transport terms for the streamwise momentum and mean kinetic energy were calculated, a similar R e threshold was revealed. These results imply that physical model studies of cross-flow turbines should achieve R e D ∼ 10 6 to properly approximate both the performance and wake dynamics of full-scale devices and arrays.
Droplet Depinning on Inclined Surfaces at High Reynolds Numbers
White, Edward; Singh, Natasha; Lee, Sungyon
2017-11-01
Contact angle hysteresis enables a sessile liquid drop to adhere to a solid surface when the surface is inclined, the drop is exposed to gas-phase flow, or the drop is exposed to both forcing modalities. Previous work by Schmucker and White (2012.DFD.M4.6) identified critical depinning Weber numbers for water drops subject to gravity- and wind-dominated forcing. This work extends the Schmucker and White data and finds the critical depinning Weber number obeys a two-slope linear model. Under pure wind forcing at Reynolds numbers above 1500 and with zero surface inclination, Wecrit = 8.0 . For non-zero inclinations, α, Wecrit decreases proportionally to A Bo sinα where A is the drop aspect ratio and Bo is its Bond number. The same relationship holds for α behavior. Supported by the National Science Foundation through Grant CBET-1605947.
Effects of viscoelasticity in the high Reynolds number cylinder wake
Richter, David
2012-01-16
At Re = 3900, Newtonian flow past a circular cylinder exhibits a wake and detached shear layers which have transitioned to turbulence. It is the goal of the present study to investigate the effects which viscoelasticity has on this state and to identify the mechanisms responsible for wake stabilization. It is found through numerical simulations (employing the FENE-P rheological model) that viscoelasticity greatly reduces the amount of turbulence in the wake, reverting it back to a state which qualitatively appears similar to the Newtonian mode B instability which occurs at lower Re. By focusing on the separated shear layers, it is found that viscoelasticity suppresses the formation of the Kelvin-Helmholtz instability which dominates for Newtonian flows, consistent with previous studies of viscoelastic free shear layers. Through this shear layer stabilization, the viscoelastic far wake is then subject to the same instability mechanisms which dominate for Newtonian flows, but at far lower Reynolds numbers. © Copyright Cambridge University Press 2012.
Flow instabilities behind rotating bluff bodies for moderate Reynolds number
Goujon-Durand, Sophie; Gibi?Ski, Kornel; Skarysz, Maciej; Wesfreid, Jose Eduardo
2015-11-01
We present experiments to study the flow behind 3D bodies (spheres, disks and propellers) rotating about an axis aligned with the streamwise direction. The experiments has been performed in a water channel using LIF visualizations and PIV measurements. We study the flow evolution and the different flow regimes as a function of two control parameters: the Reynolds number Re and the dimensionless rotation or swirl rate Ω which is the ratio of the maximum azimuthal velocity of the body to the free stream velocity. In the present investigation, we covers the range of Re smaller than 400 and Ω from 0 to 4 in some cases. Different wakes regimes such as an axisymmetric base flow (or n-symmetric in the case of propellers), low frequency helicoidal states and higher frequency state are observed. The transitions between states are studied measuring the amplitude of the azimuthal modes components of the streamwise vorticity obtained by Fourier decomposition.
The Aerodynamics of Deforming Wings at Low Reynolds Number
Medina, Albert
responsive to flexibility satisfying an inverse proportionality to stiffness. In hover, an effective pitch angle can be defined in a flexible wing that accounts for deflection which shifts results toward trend lines of rigid wings. Three-dimensional simulations examining the effects of two distinct deformation modes undergoing prescribed deformation associated with root and tip deflection demonstrated a greater aerodynamic response to tip deflection in hover. Efficiency gains in flexion wings over rigid wing counterpart were shown to be dependent on Reynolds number with efficiency in both modes increasing with increased Reynolds number. Additionally, while the leading-edge vortex axis proved insensitive to deformation, the shape and orientation of the LEV core is modified. Experiments on three-dimensional dynamically-scaled fruit fly wings with passive deformation operating in the bursting limit Reynolds number regime revealed enhanced leading-edge vortex bursting with tip deflection promoting greater LEV core flow deceleration in stroke. Experimental studies on rotary wings highlights a universal formation time of the leading-edge vortex independent of Reynolds number, acceleration profile and aspect ratio. Efforts to replicate LEV bursting phenomena of higher aspect ratio wings in a unity aspect ratio wing such that LEV growth is no limited by span but by the LEV traversing the chord revealed a flow regime of oscillatory lift generation reminiscent of behavior exhibited in translating wings that also maintains magnitude peak to peak.
Numerical simulation of high Reynolds number bubble motion
Energy Technology Data Exchange (ETDEWEB)
McLaughlin, J.B. [Clarkson Univ., Potsdam, NY (United States)
1995-12-31
This paper presents the results of numerical simulations of bubble motion. All the results are for single bubbles in unbounded fluids. The liquid phase is quiescent except for the motion created by the bubble, which is axisymmetric. The main focus of the paper is on bubbles that are of order 1 mm in diameter in water. Of particular interest is the effect of surfactant molecules on bubble motion. Results for the {open_quotes}insoluble surfactant{close_quotes} model will be presented. These results extend research by other investigators to finite Reynolds numbers. The results indicate that, by assuming complete coverage of the bubble surface, one obtains good agreement with experimental observations of bubble motion in tap water. The effect of surfactant concentration on the separation angle is discussed.
Manipulating low-Reynolds-number flow by a watermill
Zhu, Lailai; Stone, Howard
2017-11-01
Cilia and filaments have evolved in nature to achieve swimming, mixing and pumping at low Reynolds number. Their unique capacity has inspired a variety of biomimetic strategies employing artificial slender structures to manipulate flows in microfluidic devices. Most of them have to rely on an external field, such as magnetic or electric fields to actuate the slender structures actively. In this talk, we will present a new approach of utilizing the underlying flow alone to drive these structures passively. We investigate theoretically and numerically a watermill composing several rigid slender rods in simple flows. Slender body theory with and without considering hydrodynamic interactions is adopted. The theoretical predictions agree qualitatively with the numerical results and quantitatively in certain configurations. A VR International Postdoc Grant from Swedish Research Council ``2015-06334'' (L.Z.) is gratefully acknowledged.
Numerical study of rowing hydrofoil performance at low Reynolds numbers
Chung, M.-H.
2008-04-01
In this paper, the hydrodynamic performance of a 2-D flat-plate hydrofoil in rowing motion is numerically studied by a Cartesian grid method with the cut-cell approach. Adaptive mesh refinement is used to save on the number of mesh cells without harming spatial resolution in critical regions. The rowing kinematics of the hydrofoil is the same for all simulations in this work. The design parameters studied are the reduced frequency of the rowing motion, the heave amplitude, and the time lags of the feathered-to-broadside rotation and the broadside-to-feathered rotation. Results show that larger thrust and efficiency can be attained if the feathered-to-broadside rotation is started right after the beginning of the power stroke and the broadside-to-feathered rotation is finished right before the end of the power stroke. Finally, both the thrust and the efficiency increase with Reynolds number.
Eisfeld, Bernhard; Rumsey, Chris; Togiti, Vamshi
2015-01-01
The implementation of the SSG/LRR-omega differential Reynolds stress model into the NASA flow solvers CFL3D and FUN3D and the DLR flow solver TAU is verified by studying the grid convergence of the solution of three different test cases from the Turbulence Modeling Resource Website. The model's predictive capabilities are assessed based on four basic and four extended validation cases also provided on this website, involving attached and separated boundary layer flows, effects of streamline curvature and secondary flow. Simulation results are compared against experimental data and predictions by the eddy-viscosity models of Spalart-Allmaras (SA) and Menter's Shear Stress Transport (SST).
Direct numerical simulation of moderate-Reynolds-number flow past arrays of rotating spheres
Zhou, Qiang; Fan, Liang-Shih
2015-07-01
Direct numerical simulations with an immersed boundary-lattice Boltzmann method are used to investigate the effects of particle rotation on flows past random arrays of mono-disperse spheres at moderate particle Reynolds numbers. This study is an extension of a previous study of the authors [Q. Zhou and L.-S. Fan, "Direct numerical simulation of low-Reynolds-number flow past arrays of rotating spheres," J. Fluid Mech. 765, 396-423 (2015)] that explored the effects of particle rotation at low particle Reynolds numbers. The results of this study indicate that as the particle Reynolds number increases, the normalized Magnus lift force decreases rapidly when the particle Reynolds number is in the range lower than 50. For the particle Reynolds number greater than 50, the normalized Magnus lift force approaches a constant value that is invariant with solid volume fractions. The proportional dependence of the Magnus lift force on the rotational Reynolds number (based on the angular velocity and the diameter of the spheres) observed at low particle Reynolds numbers does not change in the present study, making the Magnus lift force another possible factor that can significantly affect the overall dynamics of fluid-particle flows other than the drag force. Moreover, it is found that both the normalized drag force and the normalized torque increase with the increase of the particle Reynolds number and the solid volume fraction. Finally, correlations for the drag force, the Magnus lift force, and the torque in random arrays of rotating spheres at arbitrary solids volume fractions, rotational Reynolds numbers, and particle Reynolds numbers are formulated.
Staiber, Wolfgang
2014-07-01
Unequal chromosome segregation and spindle formation occurs in the last gonial mitosis in the germ line of the chironomid Acricotopus lucidus. During this differential mitosis, all germ line-limited chromosomes (=Ks) migrate undivided to only one pole of the cell, while the somatic chromosomes (=Ss) first remain in the metaphase plane, and with the arrival of the Ks at the pole, they then separate equally. The evolutionarily conserved GTPase Ran plays a crucial role in many cellular processes. This includes the regulation of microtubule nucleation and stabilisation at kinetochores and of spindle assembly during mitosis, which is promoted by a RanGTP concentration gradient that forms around the mitotic chromosomes (Kalab et al. in Science 295:2452-2456, 2002, Nature 440:697-701, 2006). In the present study, a strong accumulation of Ran was detected by immunofluorescence at the kinetochores of the Ss in normal gonial and differential gonial mitoses of males of A. lucidus. In contrast, no Ran accumulation was observed at the kinetochores of the Ss in the metaphases of brain ganglia mitoses or of aberrant spermatocytes or in metaphases I and II of spermatocyte meiotic divisions. Likewise, there was no accumulation at the kinetochores of Drosophila melanogaster mitotic chromosomes from larval brains. The specific accumulation of Ran at the kinetochores of the Ss in differential gonial mitoses of A. lucidus strongly suggests that Ran is involved in a mechanism acting in this exceptional mitosis, which retains the Ss at the metaphase plane and prevents a premature separation and unequal segregation of the Ss during monopolar migration of the Ks.
Rinfoform Usage As Update Request Media Articles In iRAN
Directory of Open Access Journals (Sweden)
Untung Rahardja
2016-10-01
Full Text Available Ease of access to information made public should continue to improve his knowledge of information technology. As one of the Universities in the field of computers, Perguruan Tinggi Raharja has a lot of innovation to create pembelajalan unconventional media. For that create an information media that serve as a center of tutorial every innovation in Perguruan Tinggi Raharja. iRAN (iLeraning Prog Ask And News. In the implementation one that is still seen as less is a service request in Iran. Utilization of Cloud Computing RinfoApps as media RinfoForms one of them is deemed to cover deficiencies that affect the improvements in the services provided.This research was conducted using the method of data collection, including the method of observation, and literature study method. RinfoForm expected utilization associated with Cluod Computin can give effect to the service request is in Iran.
A RANS modelling approach for predicting powering performance of ships in waves
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Björn Windén
2014-06-01
Full Text Available In this paper, a modelling technique for simulating self-propelled ships in waves is presented. The flow is modelled using a RANS solver coupled with an actuator disk model for the propeller. The motion of the ship is taken into consideration in the definition of the actuator disk region as well as the advance ratio of the propeller. The RPM of the propeller is controlled using a PID-controller with constraints added on the maximum permissible RPM increase rate. Results are presented for a freely surging model in regular waves with different constraints put on the PID-controller. The described method shows promising results and allows for the studying of several factors relating to self-propulsion. However, more validation data is needed to judge the accuracy of the model.
Optimizing small cell deployment by the use of C-RANs
DEFF Research Database (Denmark)
Checko, Aleksandra; Holm, Henrik Laumand; Christiansen, Henrik Lehrmann
2014-01-01
conditions. Furthermore, based on theoretical calculations and Network simulations we present considerations on deployment scenarios to optimize green field deployments in terms of Total Cost of Ownership (TCO). This involves optimizing the mix of cells with different traffic profiles and the BBU Pool......A Cloud Radio Access Network (C-RAN) is a novel mobile network architecture that has the potential to support extremely dense mobile network deployments enhancing the network capacity while offering cost savings on baseband resources. In this work we analyze cell traffic profiles and evaluate...... the conditions that impact the statistical multiplexing gain in the Baseband Unit (BBU) Pool. We conclude on the set of parameters that maximize the statistical multiplexing gain, leading to the highest potential cost savings. We then propose a packet based architecture that can adapt to changing traffic...
Galaxy evolution. Isolated compact elliptical galaxies: stellar systems that ran away.
Chilingarian, Igor; Zolotukhin, Ivan
2015-04-24
Compact elliptical galaxies form a rare class of stellar system (~30 presently known) characterized by high stellar densities and small sizes and often harboring metal-rich stars. They were thought to form through tidal stripping of massive progenitors, until two isolated objects were discovered where massive galaxies performing the stripping could not be identified. By mining astronomical survey data, we have now found 195 compact elliptical galaxies in all types of environment. They all share similar dynamical and stellar population properties. Dynamical analysis for nonisolated galaxies demonstrates the feasibility of their ejection from host clusters and groups by three-body encounters, which is in agreement with numerical simulations. Hence, isolated compact elliptical and isolated quiescent dwarf galaxies are tidally stripped systems that ran away from their hosts. Copyright © 2015, American Association for the Advancement of Science.
A RANS/DES Numerical Procedure for Axisymmetric Flows with and without Strong Rotation
Energy Technology Data Exchange (ETDEWEB)
Andrade, Andrew Jacob [Univ. of California, Davis, CA (United States)
2007-01-01
A RANS/DES numerical procedure with an extended Lax-Wendroff control-volume scheme and turbulence model is described for the accurate simulation of internal/external axisymmetric flow with and without strong rotation. This new procedure is an extension, from Cartesian to cylindrical coordinates, of (1) a second order accurate multi-grid, control-volume integration scheme, and (2) a k-ω turbulence model. This paper outlines both the axisymmetric corrections to the mentioned numerical schemes and the developments of techniques pertaining to numerical dissipation, multi-block connectivity, parallelization, etc. Furthermore, analytical and experimental case studies are presented to demonstrate accuracy and computational efficiency. Notes are also made toward numerical stability of highly rotational flows.
A Synthesis of Hybrid RANS/LES CFD Results for F-16XL Aircraft Aerodynamics
Luckring, James M.; Park, Michael A.; Hitzel, Stephan M.; Jirasek, Adam; Lofthouse, Andrew J.; Morton, Scott A.; McDaniel, David R.; Rizzi, Arthur M.
2015-01-01
A synthesis is presented of recent numerical predictions for the F-16XL aircraft flow fields and aerodynamics. The computational results were all performed with hybrid RANS/LES formulations, with an emphasis on unsteady flows and subsequent aerodynamics, and results from five computational methods are included. The work was focused on one particular low-speed, high angle-of-attack flight test condition, and comparisons against flight-test data are included. This work represents the third coordinated effort using the F-16XL aircraft, and a unique flight-test data set, to advance our knowledge of slender airframe aerodynamics as well as our capability for predicting these aerodynamics with advanced CFD formulations. The prior efforts were identified as Cranked Arrow Wing Aerodynamics Project International, with the acronyms CAWAPI and CAWAPI-2. All information in this paper is in the public domain.
High average power supercontinuum sources
Indian Academy of Sciences (India)
The physical mechanisms and basic experimental techniques for the creation of high average spectral power supercontinuum sources is briefly reviewed. We focus on the use of high-power ytterbium-doped fibre lasers as pump sources, and the use of highly nonlinear photonic crystal fibres as the nonlinear medium.
Polyhedral Painting with Group Averaging
Farris, Frank A.; Tsao, Ryan
2016-01-01
The technique of "group-averaging" produces colorings of a sphere that have the symmetries of various polyhedra. The concepts are accessible at the undergraduate level, without being well-known in typical courses on algebra or geometry. The material makes an excellent discovery project, especially for students with some background in…
Fuzzy Weighted Average: Analytical Solution
van den Broek, P.M.; Noppen, J.A.R.
2009-01-01
An algorithm is presented for the computation of analytical expressions for the extremal values of the α-cuts of the fuzzy weighted average, for triangular or trapeizoidal weights and attributes. Also, an algorithm for the computation of the inverses of these expressions is given, providing exact
Gaussian moving averages and semimartingales
DEFF Research Database (Denmark)
Basse-O'Connor, Andreas
2008-01-01
are constructive - meaning that they provide a simple method to obtain kernels for which the moving average is a semimartingale or a Wiener process. Several examples are considered. In the last part of the paper we study general Gaussian processes with stationary increments. We provide necessary and sufficient...
Measurement Invariance of the Reynolds Depression Adolescent Scale across Gender and Age
Fonseca-Pedrero, Eduardo; Wells, Craig; Paino, Mercedes; Lemos-Giraldez, Serafin; Villazon-Garcia, Ursula; Sierra, Susana; Garcia-Portilla Gonzalez, Ma Paz; Bobes, Julio; Muniz, Jose
2010-01-01
The main objective of the present study was to examine measurement invariance of the Reynolds Depression Adolescent Scale (RADS) (Reynolds, 1987) across gender and age in a representative sample of nonclinical adolescents. The sample was composed of 1,659 participants, 801 males (48.3%), with a mean age of 15.9 years (SD = 1.2). Confirmatory…
Effects of non-uniform interfacial tension in small Reynolds number ...
Indian Academy of Sciences (India)
Taylor and Acrivos [1] considered the problem of small Reynolds number flow past a spherical liquid drop with uniform interfacial tension between the liquid drop and the sur- rounding fluid. The problem is a singular perturbation problem and Taylor and Acrivos calculated the solution to first order in the Reynolds number.
Unsteady behavior of a confined jet in a cavity at moderate Reynolds numbers
Energy Technology Data Exchange (ETDEWEB)
Bouchet, G [Laboratoire IUSTI, UMR 7343 CNRS, Aix Marseille Universite, 5 rue Enrico Fermi, 13453 Marseille Cedex 13 (France); Climent, E, E-mail: Gilles.Bouchet@univ-amu.fr, E-mail: Gilles.Bouchet@univ-provence.fr, E-mail: climent@imft.fr [Institut de Mecanique des Fluides de Toulouse, UMR 5502 Universite de Toulouse-CNRS-INPT-UPS, 1 allee du Professeur Camille Soula, 31400 Toulouse (France)
2012-04-01
Self-sustained oscillations in the sinuous mode are observed when a jet impinges on a rigid surface. Confined jet instability is experimentally and numerically investigated here at moderate Reynolds numbers. When the Reynolds number is varied, the dynamic response of the jet is unusual in comparison with that of similar configurations (hole-tone, jet edge, etc). Modal transitions are clearly detected when the Reynolds number is varied. However, these transitions result in a reduction of the frequency, which means that the wavelength grows with Reynolds number. Moreover, the instability that sets in at low Reynolds number, as a subcritical Hopf bifurcation, disappears only 25% above the threshold. Then, the flow becomes steady again and symmetric. This atypical behavior is compared with our previous study on a submerged fountain (Bouchet et al 2002 Europhys. Lett. 59 826). (paper)
Nimmagadda, Rajesh; Venkatasubbaiah, K.
2017-06-01
The present study investigates the laminar forced convection flow of single walled carbon nanotube (SWCNT), gold (Au), aluminum oxide (Al2O3), silver (Ag) and hybrid (Al2O3 + Ag) nanofluids (HyNF) in a wide rectangular micro-channel at low Reynolds numbers. The heat transfer characteristics of de-ionized (DI) water and SWCNT nanofluid with different nanoparticle volume concentrations have been experimental studied. Furthermore, numerical study has also been carried out to investigate the flow and heat transfer characteristics of DI water, SWCNT, Au, Al2O3, Ag and HyNF at different Reynolds numbers with different nanoparticle volume concentrations and particle diameters. The numerical study consider the effects of both inertial and viscous forces by solving the full Navier-Stokes equations at low Reynolds numbers. A two dimensional conjugate heat transfer multiphase mixture model has been developed and used for numerical study. A significant enhancement in the average Nusselt number is observed both experimentally and numerically for nanofluids. The study presents four optimized combinations of nanofluids (1 vol% SWCNT and 1 vol% Au with d_p = 50 nm), (2 vol% SWCNT and 3 vol% Au with d_p = 70 nm), (3 vol% Al2O3 and 2 vol% Au with d_p = 70 nm) as well as (3 vol% HyNF (2.4% Al2O3 + 0.6% Ag) and 3 vol% Au with d_p = 50 nm) that provides a better switching option in choosing efficient working fluid with minimum cost based on cooling requirement. The conduction phenomenon of the solid region at bottom of the micro-channel is considered in the present investigation. This phenomenon shows that the interface temperature between solid and fluid region increases along the length of the channel. The present results has been validated with the experimental and numerical results available in the literature.
2013-06-06
... Freeport-McMoRan Energy LLC; Application for Long-Term Authorization To Export Liquefied Natural Gas... natural gas (non-FTA countries) with which trade is not prohibited by U.S. law or policy. FME requests... Natural Gas Act (NGA), 15 U.S.C. 717b(c).\\3\\ In the current Application, FME requests both FTA and non...
Kalkman, I.M.; Bronkhorst, A.J.; Bentum, C.A. van; Franke, J.
2012-01-01
Five root-mean-square (RMS) pressure models are used in combination with different turbulence models to determine whether it is possible to obtain a conservative estimate of RMS pressures on a high-rise building model from a RANS calculation. When a precursor domain is used for the generation of
HIV Integration Targeting: A Pathway Involving Transportin-3 and the Nuclear Pore Protein RanBP2
Huegel, Alyssa; Roth, Shoshannah L.; Schaller, Torsten; James, Leo C.; Towers, Greg J.; Young, John A. T.; Chanda, Sumit K.; König, Renate; Malani, Nirav; Berry, Charles C.; Bushman, Frederic D.
2011-01-01
Genome-wide siRNA screens have identified host cell factors important for efficient HIV infection, among which are nuclear pore proteins such as RanBP2/Nup358 and the karyopherin Transportin-3/TNPO3. Analysis of the roles of these proteins in the HIV replication cycle suggested that correct trafficking through the pore may facilitate the subsequent integration step. Here we present data for coupling between these steps by demonstrating that depletion of Transportin-3 or RanBP2 altered the terminal step in early HIV replication, the selection of chromosomal sites for integration. We found that depletion of Transportin-3 and RanBP2 altered integration targeting for HIV. These knockdowns reduced HIV integration frequency in gene-dense regions and near gene-associated features, a pattern that differed from that reported for depletion of the HIV integrase binding cofactor Psip1/Ledgf/p75. MLV integration was not affected by the Transportin-3 knockdown. Using siRNA knockdowns and integration targeting analysis, we also implicated several additional nuclear proteins in proper target site selection. To map viral determinants of integration targeting, we analyzed a chimeric HIV derivative containing MLV gag, and found that the gag replacement phenocopied the Transportin-3 and RanBP2 knockdowns. Thus, our data support a model in which Gag-dependent engagement of the proper transport and nuclear pore machinery mediate trafficking of HIV complexes to sites of integration. PMID:21423673
HIV integration targeting: a pathway involving Transportin-3 and the nuclear pore protein RanBP2.
Directory of Open Access Journals (Sweden)
Karen E Ocwieja
2011-03-01
Full Text Available Genome-wide siRNA screens have identified host cell factors important for efficient HIV infection, among which are nuclear pore proteins such as RanBP2/Nup358 and the karyopherin Transportin-3/TNPO3. Analysis of the roles of these proteins in the HIV replication cycle suggested that correct trafficking through the pore may facilitate the subsequent integration step. Here we present data for coupling between these steps by demonstrating that depletion of Transportin-3 or RanBP2 altered the terminal step in early HIV replication, the selection of chromosomal sites for integration. We found that depletion of Transportin-3 and RanBP2 altered integration targeting for HIV. These knockdowns reduced HIV integration frequency in gene-dense regions and near gene-associated features, a pattern that differed from that reported for depletion of the HIV integrase binding cofactor Psip1/Ledgf/p75. MLV integration was not affected by the Transportin-3 knockdown. Using siRNA knockdowns and integration targeting analysis, we also implicated several additional nuclear proteins in proper target site selection. To map viral determinants of integration targeting, we analyzed a chimeric HIV derivative containing MLV gag, and found that the gag replacement phenocopied the Transportin-3 and RanBP2 knockdowns. Thus, our data support a model in which Gag-dependent engagement of the proper transport and nuclear pore machinery mediate trafficking of HIV complexes to sites of integration.
Fernandez Mora, Maria de Los Angeles; Ribberink, Jan S.; van der Zanden, Joep; van der Werf, Jebbe J.; Jacobsen, N.G.; Lynett, P.; Lynett, Patrick
2017-01-01
A 2D RANS-VOF model is used to simulate the flow and sand transport for two different full-scale laboratory experiments: i) non-breaking waves over a horizontal sand bed (Schretlen et al., 2011) and ii) plunging breaking waves over a barred mobile bed profile (Van der Zanden et al., 2016). For the
Shear-driven dynamo waves at high magnetic Reynolds number.
Tobias, S M; Cattaneo, F
2013-05-23
Astrophysical magnetic fields often display remarkable organization, despite being generated by dynamo action driven by turbulent flows at high conductivity. An example is the eleven-year solar cycle, which shows spatial coherence over the entire solar surface. The difficulty in understanding the emergence of this large-scale organization is that whereas at low conductivity (measured by the magnetic Reynolds number, Rm) dynamo fields are well organized, at high Rm their structure is dominated by rapidly varying small-scale fluctuations. This arises because the smallest scales have the highest rate of strain, and can amplify magnetic field most efficiently. Therefore most of the effort to find flows whose large-scale dynamo properties persist at high Rm has been frustrated. Here we report high-resolution simulations of a dynamo that can generate organized fields at high Rm; indeed, the generation mechanism, which involves the interaction between helical flows and shear, only becomes effective at large Rm. The shear does not enhance generation at large scales, as is commonly thought; instead it reduces generation at small scales. The solution consists of propagating dynamo waves, whose existence was postulated more than 60 years ago and which have since been used to model the solar cycle.
Flow analysis of the low Reynolds number swimmer C. elegans
Montenegro-Johnson, Thomas D.; Gagnon, David A.; Arratia, Paulo E.; Lauga, Eric
2016-09-01
Swimming cells and microorganisms are a critical component of many biological processes. In order to better interpret experimental studies of low Reynolds number swimming, we combine experimental and numerical methods to perform an analysis of the flow field around the swimming nematode Caenorhabditis elegans. We first use image processing and particle tracking velocimetry to extract the body shape, kinematics, and flow fields around the nematode. We then construct a three-dimensional model using the experimental swimming kinematics and employ a boundary element method to simulate flow fields, obtaining very good quantitative agreement with experiment. We use this numerical model to show that calculation of flow shear rates using purely planar data results in significant underestimates of the true three-dimensional value. Applying symmetry arguments, validated against numerics, we demonstrate that the out-of-plane contribution can be accounted for via incompressibility and therefore simply calculated from particle tracking velocimetry. Our results show how fundamental fluid mechanics considerations may be used to improve the accuracy of measurements in biofluiddynamics.
Minimum state for high Reynolds and Peclet number turbulent flows
Energy Technology Data Exchange (ETDEWEB)
Zhou Ye, E-mail: yezhou@llnl.go [Lawrence Livermore National Laboratory, PO Box 808, Livermore, CA 94551 (United States); Buckingham, A.C. [Lawrence Livermore National Laboratory, PO Box 808, Livermore, CA 94551 (United States); Bataille, F. [PROMES-CNRS, Tecnosud, 66100 Perpignan (France); Mathelin, L. [LIMSI-CNRS, BP 133, 91403 Orsay (France)
2009-07-20
Direct numerical simulations (DNS) or experiments for the very high Reynolds (Re) and Peclet (Pe) number flows commonly exceed the resolution possible even when use is made of the most advanced computer capability or most sophisticated diagnostics and physical capabilities of advanced laboratory facilities. In practice use is made of statistical flow data bases developed at the highest Re and Pe levels achievable within the currently available facility limitations. In addition, there is presently no metric to indicate whether and how much of the fully resolved physics of the flow of interest has been captured within the facilities available. In this Letter the authors develop the necessary metric criteria for homogeneous, isotropic and shear layer flows. It is based on establishing a smaller subset of the total range of dynamic scale interactions that will still faithfully reproduce all of the essential, significant, influences of the larger range of scale interactions. The work identifies a minimum significant Re and Pe level that must be obtained by DNS or experiment in order to capture all of the significant dynamic influences in data which is then scaleable to flows of interest. Hereafter this is called the minimum state. Determination of the minimum state is based on finding a minimum scale separation for the energy-containing scales of the flow and scalar fields sufficient to prevent contamination by interaction with the (non-universal) velocity dissipation and scalar diffusivity inertial range scale limits.
A coin vibrational motor swimming at low Reynolds number
Quillen, Alice C; Kelley, Douglas H; Friedmann, Tamar; Oakes, Patrick W
2016-01-01
Low-cost coin vibrational motors, used in haptic feedback, exhibit rotational internal motion inside a rigid case. Because the motor case motion exhibits rotational symmetry, when placed into a fluid such as glycerin, the motor does not swim even though its vibrations induce steady streaming in the fluid. However, a piece of rubber foam stuck to the curved case and giving the motor neutral buoyancy also breaks the rotational symmetry allowing it to swim. We measured a 1 cm diameter coin vibrational motor swimming in glycerin at a speed of a body length in 3 seconds or at 3 mm/s. The swim speed puts the vibrational motor in a low Reynolds number regime similar to bacterial motility, but because of the vibration it is not analogous to biological organisms. Rather the swimming vibrational motor may inspire small inexpensive robotic swimmers that are robust as they contain no external moving parts. A time dependent Stokes equation planar sheet model suggests that the swim speed depends on a steady streaming veloc...
Free and confined jets at low Reynolds numbers
Koller-Milojevie, Dušica; Schneider, Wilhelm
1993-12-01
Free jets, and jets with tubular confinements, are investigated in the jet Reynolds number regime 80 ⩽ Re j ⩽ 1000 being of interest for micro-jet pumps, among other applications. For issuing the jets, conventional (single-hole) nozzles as well as dual-hole nozzles of a particular design are used. Both flow visualization and LDA measurement indicate that, in agreement with previous findings, the jets issuing from conventional nozzles remain laminar up to large distances from the orifice. Thus there is but little entrainment of ambient fluid, and the performance of conventional nozzles in micro-jet pumps is rather poor. The dual-hole nozzles, on the other hand, are found to enforce transition to turbulent flow near the orifices. As a result, the entrainment rate is considerably increased, and the performance of jet pumps is improved when the dual-hole nozzles are applied. The experimental data are found to be in fair agreement with predictions based on mass and momentum balances.
Unsteady flow over flexible wings at different low Reynolds numbers
Directory of Open Access Journals (Sweden)
Genç Mustafa Serdar
2016-01-01
Full Text Available In this study, unsteady flow around flexible membrane wing which had aspect ratio of 1 (AR=1 was investigated experimentally at various Reynolds numbers (Re = 25000 and Re = 50000. Smoke-wire technique for flow visualization over the flexible membrane wing was utilized in the experiments. Digital Image Correlation system (DIC was used for measuring deformation of AR = 1 flexible membrane wing. Instantaneous deformation measurements of membrane wing were combined with the flow field measurements. In low aspect ratio flexible membrane wings, unsteadiness includes tip vortices and vortex shedding, and the combination of tip vortices. In these types of wings, complex unsteady deformations occurred due to vortex shedding. The results showed that the increasing angle of attack results in increase of membrane deformation. Moreover, it was concluded that analysis of the instantaneous deformation revealed chordwise and spanwise, modes which were due to the shedding of leading-edge vortices as well as tip vortices. Consequently, vibrational mode decreased and maximum standard deviation location approached to the trailing edge by reason of increasing angle of attack.
Directory of Open Access Journals (Sweden)
Daniel R Scoles
Full Text Available Spinocerebellar ataxia type 2 (SCA2 is a progressive autosomal dominant disorder caused by the expansion of a CAG tract in the ATXN2 gene. The SCA2 disease phenotype is characterized by cerebellar atrophy, gait ataxia, and slow saccades. ATXN2 mutation causes gains of toxic and normal functions of the ATXN2 gene product, ataxin-2, and abnormally slow Purkinje cell firing frequency. Previously we investigated features of ATXN2 controlling expression and noted expression differences for ATXN2 constructs with varying CAG lengths, suggestive of repeat associated non-AUG translation (RAN translation. To determine whether RAN translation occurs for ATXN2 we assembled various ATXN2 constructs with ATXN2 tagged by luciferase, HA or FLAG tags, driven by the CMV promoter or the ATXN2 promoter. Luciferase expression from ATXN2-luciferase constructs lacking the ATXN2 start codon was weak vs AUG translation, regardless of promoter type, and did not increase with longer CAG repeat lengths. RAN translation was detected on western blots by the anti-polyglutamine antibody 1C2 for constructs driven by the CMV promoter but not the ATXN2 promoter, and was weaker than AUG translation. Strong RAN translation was also observed when driving the ATXN2 sequence with the CMV promoter with ATXN2 sequence downstream of the CAG repeat truncated to 18 bp in the polyglutamine frame but not in the polyserine or polyalanine frames. Our data demonstrate that ATXN2 RAN translation is weak compared to AUG translation and is dependent on ATXN2 sequences flanking the CAG repeat.
Self-Averaging Expectation Propagation
DEFF Research Database (Denmark)
Cakmak, Burak; Opper, Manfred; Fleury, Bernard Henri
We investigate the problem of approximate inference using Expectation Propagation (EP) for large systems under some statistical assumptions. Our approach tries to overcome the numerical bottleneck of EP caused by the inversion of large matrices. Assuming that the measurement matrices...... are realizations of specific types of random matrix ensembles – called invariant ensembles – the EP cavity variances have an asymptotic self-averaging property. They can be pre-computed using specific generating functions which do not require matrix inversions. We demonstrate the performance of our approach...
RICHTER, DAVID
2010-03-29
The results from a numerical investigation of inertial viscoelastic flow past a circular cylinder are presented which illustrate the significant effect that dilute concentrations of polymer additives have on complex flows. In particular, effects of polymer extensibility are studied as well as the role of viscoelasticity during three-dimensional cylinder wake transition. Simulations at two distinct Reynolds numbers (Re = 100 and Re = 300) revealed dramatic differences based on the choice of the polymer extensibility (L2 in the FENE-P model), as well as a stabilizing tendency of viscoelasticity. For the Re = 100 case, attention was focused on the effects of increasing polymer extensibility, which included a lengthening of the recirculation region immediately behind the cylinder and a sharp increase in average drag when compared to both the low extensibility and Newtonian cases. For Re = 300, a suppression of the three-dimensional Newtonian mode B instability was observed. This effect is more pronounced for higher polymer extensibilities where all three-dimensional structure is eliminated, and mechanisms for this stabilization are described in the context of roll-up instability inhibition in a viscoelastic shear layer. © 2010 Cambridge University Press.
Reynolds and swirl number effects on turbulent pipe flow in a 90 degree pipe bend
Kalpakli, Athanasia; Oerlue, Ramis; Alfredsson, P. Henrik
2011-11-01
Flows in pipe bends have been studied extensively over the last decades due to their occurrence both in the human respiratory and blood systems as well as in many technical applications. The centrifugal effect of the bend may give rise to Dean vortices and the behaviour of these has been of particular interest. While their motion has nicely been illustrated in laminar flows, the picture of their motion in turbulent flows remains rather blurred. Within the framework of the present work, fully developed turbulent pipe flow from a 100 diameter (D) long pipe is fed to a 90° bend and the flow field at 0 . 5 D downstream the bend has been studied by means of Time-Resolved Stereoscopic Particle Image Velocimetry, covering a Reynolds number range from 7000 to 34000 based on bulk velocity (Ub) and D. Additionally, a well defined swirl profile could be introduced by rotating the 100 D long straight pipe along its axis, yielding a variation in swirl number (S), defined as the ratio between the azimuthal velocity of the pipe wall and Ub, from 0 (the non-rotating case) to 1.2. The three-dimensional time-averaged and instantaneous flow field illustrating the symmetrical Dean vortices for S = 0 and the influence by the swirling motion for S ≠ 0 , the so-called ``swirl-switching phenomenon,'' as well as the large-scale structures will be presented and discussed.
Hydrodynamic interaction on large-Reynolds-number aligned bubbles: Drag effects
Energy Technology Data Exchange (ETDEWEB)
Ramirez-Munoz, J., E-mail: jrm@correo.azc.uam.mx [Departamento de Energia, Universidad Autonoma Metropolitana-Azcapotzalco, Av. San Pablo 180, Col. Reynosa Tamaulipas, 02200 Mexico D.F. (Mexico); Centro de Investigacion en Polimeros, Marcos Achar Lobaton No. 2, Tepexpan, 55885 Acolman, Edo. de Mexico (Mexico); Salinas-Rodriguez, E.; Soria, A. [Departamento de IPH, Universidad Autonoma Metropolitana-Iztapalapa, San Rafael Atlixco 186, Col. Vicentina, Iztapalapa, 09340 Mexico D.F. (Mexico); Gama-Goicochea, A. [Centro de Investigacion en Polimeros, Marcos Achar Lobaton No. 2, Tepexpan, 55885 Acolman, Edo. de Mexico (Mexico)
2011-07-15
Graphical abstract: Display Omitted Highlights: > The hydrodynamic interaction of a pair aligned equal-sized bubbles is analyzed. > The leading bubble wake decreases the drag on the trailing bubble. > A new semi-analytical model for the trailing bubble's drag is presented. > The equilibrium distance between bubbles is predicted. - Abstract: The hydrodynamic interaction of two equal-sized spherical gas bubbles rising along a vertical line with a Reynolds number (Re) between 50 and 200 is analyzed. An approach to estimate the trailing bubble drag based on the search of a proper reference fluid velocity is proposed. Our main result is a new, simple semi-analytical model for the trailing bubble drag. Additionally, the equilibrium separation distance between bubbles is predicted. The proposed models agree quantitatively up to small distances between bubbles, with reported data for 50 {<=} Re {<=} 200. The relative average error for the trailing bubble drag, Er, is found to be in the range 1.1 {<=} Er {<=} 1.7, i.e., it is of the same order of the analytical predictions in the literature.
Lift on a Steady Airfoil in Low Reynolds Number Shear Flow
Hammer, Patrick; Visbal, Miguel; Naguib, Ahmed; Koochesfahani, Manoochehr
2016-11-01
Current understanding of airfoil aerodynamics is primarily based on a uniform freestream velocity approaching the airfoil, without consideration for possible presence of shear in the approach flow. Inviscid theory by Tsien (1943) shows that a symmetric airfoil at zero angle of attack experiences positive lift, i.e. a shift in the zero-lift angle of attack, in the presence of positive mean shear in the approach flow. In the current work, 2D computations are conducted on a steady NACA 0012 airfoil at a chord Reynolds number of Re = 12,000, at zero angle of attack. A uniform shear profile (i.e. a linear velocity variation) is used for the approach flow by modifying the FDL3DI Navier-Stokes solver (Visbal and Gaitonde, 1999). Interestingly, opposite to the inviscid prediction of Tsien (1943), the results for the airfoil at zero angle of attack show that the average lift is negative in the shear flow. The magnitude of this lift grows as the shear rate increases. Additional results are presented regarding the physics underlying the shear effect on lift. A companion experimental study is also given in a separate presentation. This work was supported by AFOSR Award Number FA9550-15-1-0224.
Measurements of Reynolds stress in a wind-driven lagoonal estuary
Whipple, Anthony C.; Luettich, Richard A.; Seim, Harvey E.
2006-07-01
Acoustic Doppler current profilers (ADCPs) have been used to measure Reynolds stresses in tidally dominated environments where wave action was minimal. In this paper, we examine observations from a microtidal estuary where the effects of wind stress and surface waves dominate the velocity variance. Reynolds stress measurements in this setting require a technique for addressing surface gravity wave contamination. We present here a method of reducing the effect of wave motion on Reynolds stresses by subtracting coincident observations along the axis of the ADCP beam. Linear wave theory is used to account for the attenuation of wave orbital velocities with depth. Using this method, Reynolds stress values are brought in line with those predicted by drag laws at the surface and bottom. The apparent Reynolds stress that is removed by the along-axis subtraction is shown to be largely due to the interaction of a slight tilt (1°) in the ADCP and the wave orbital velocity. During periods of stronger wind and waves, there is evidence of enhanced near-surface turbulence and momentum flux, presumably due to breaking waves. During these events, our calculated Reynolds stress magnitudes still appear reasonable, although the directions are suspect. We develop a diagnostic technique that clearly demarcates this region when it occurs. Coincident density profile measurements are used with the ADCP data to compute gradient Richardson numbers throughout the water column. Enhanced Reynolds stresses appear to correspond to Richardson numbers less than one.
Reynolds Stress in the Plasma Boundary of the STOR-M Tokamak
Singh, Ajay K.; Liu, Dazhi; Livingstone, Stephen; Xiao, Chijjin; Akira, Hirose
2004-11-01
Sheared plasma flows are considered to play an important role in regulating the plasma transport and in the transition of low to high confinement regime in magnetically confined plasmas. There are several mechanisms proposed to explain the generation of sheared poloidal flows. One of the mechanism is through the generation of mean flow from plasma fluctuations via the Reynold's stress. From the examination of momentum balance equation it is apparent that poloidal flow may be nonlinearly accelerated if the turbulent Reynold's stress is finite and has a radial gradient. We present measurements of the radial profile of turbulent Reynolds stress in the boundary of STOR--M tokamak using Langmuir probes. If the plasma flow is dictated by E× B drift, the electrostatic Reynolds stress component is proportional to . The measurements show that the Reynolds stress has a radial gradient close to the velocity shear layer location. The statistical characteristics of fluctuations in the vicinity of this region suggests that gradient in Reynolds stress might drive significant poloidal flow in the plasma edge region. Study is also underway to measure Reynold's stress in the toroidal direction using a Mach probe as well as Langmuir probes.
Horizontal Axis Wind Turbine Experiments at Full-Scale Reynolds Numbers
Miller, Mark; Kiefer, Janik; Nealon, Tara; Westergaard, Carsten; Hultmark, Marcus
2017-11-01
Achieving high Reynolds numbers on a wind turbine model remains a major challenge for experimentalists. Since Reynolds number effects need to be captured accurately, matching this parameter is of great importance. The challenge stems from the large scale ratio between model and full-size, typically on the order of 1:100. Traditional wind tunnels are limited due to finite tunnel size, with velocity as the only free-parameter available for increasing the Reynolds number. Unfortunately, increasing the velocity 100 times is untenable because it violates Mach number matching with the full-scale and results in unfeasible rotation rates. Present work in Princeton University's high pressure wind tunnel makes it possible to evaluate the Reynolds number sensitivity with regard to wind turbine aerodynamics. This facility, which uses compressed air as the working fluid, allows for adjustment of the Reynolds number, via the fluid density, independent of the Tip Speed Ratio (TSR) and Mach number. Power and thrust coefficients will be shown as a function of Reynolds number and TSR for a model wind turbine. The Reynolds number range investigated exceeds 10 ×106 based on diameter and free-stream conditions or 3 ×106 based on the tip chord, matching those of the full-scale. National Science Foundation and Andlinger Center for Energy and the Environment.
Validation of the simpleFoam (RANS solver for the atmospheric boundary layer in complex terrain
Directory of Open Access Journals (Sweden)
Peralta C.
2014-01-01
Full Text Available We validate the simpleFoam (RANS solver in OpenFOAM (version 2.1.1 for simulating neutral atmospheric boundary layer flows in complex terrain. Initial and boundary conditions are given using Richards and Hoxey proposal [1]. In order to obtain stable simulation of the ABL, modified wall functions are used to set the near-wall boundary conditions, following Blocken et al remedial measures [2]. A structured grid is generated with the new library terrainBlockMesher [3,4], based on OpenFOAM's blockMesh native mesher. The new tool is capable of adding orographic features and the forest canopy. Additionally, the mesh can be refined in regions with complex orography. We study both the classical benchmark case of Askervein hill [5] and the more recent Bolund island data set [6]. Our purpose is two-folded: to validate the performance of OpenFOAM steady state solvers, and the suitability of the new meshing tool to generate high quality structured meshes, which will be used in the future for performing more computationally intensive LES simulations in complex terrain.
A Game-Theoretical Approach for Spectrum Efficiency Improvement in Cloud-RAN
Directory of Open Access Journals (Sweden)
Zhuofu Zhou
2016-01-01
Full Text Available As tremendous mobile devices access to the Internet in the future, the cells which can provide high data rate and more capacity are expected to be deployed. Specifically, in the next generation of mobile communication 5G, cloud computing is supposed to be applied to radio access network. In cloud radio access network (Cloud-RAN, the traditional base station is divided into two parts, that is, remote radio heads (RRHs and base band units (BBUs. RRHs are geographically distributed and densely deployed, so as to achieve high data rate and low latency. However, the ultradense deployment inevitably deteriorates spectrum efficiency due to the severer intercell interference among RRHs. In this paper, the downlink spectrum efficiency can be improved through the cooperative transmission based on forming the coalitions of RRHs. We formulate the problem as a coalition formation game in partition form. In the process of coalition formation, each RRH can join or leave one coalition to maximize its own individual utility while taking into account the coalition utility at the same time. Moreover, the convergence and stability of the resulting coalition structure are studied. The numeric simulation result demonstrates that the proposed approach based on coalition formation game is superior to the noncooperative method in terms of the aggregate coalition utility.
RANS SIMULATION OF HYDROFOIL EFFECTS ON HYDRODYNAMIC COEFFICIENTS OF A PLANING CATAMARAN
Directory of Open Access Journals (Sweden)
Amin Najafi
2016-03-01
Full Text Available Determination of high-speed crafts’ hydrodynamic coefficients will help to analyze the dynamics of these kinds of vessels and the factors affecting their dynamic stabilities. Also, it can be useful and effective in controlling the vessel instabilities. The main purpose of this study is to determine the coefficients of longitudinal motions of a planing catamaran with and without a hydrofoil using RANS method to evaluate the foil effects on them. Determination of hydrodynamic coefficients by experimental approach is costly, and requires meticulous laboratory equipment; therefore, utilizing numerical methods and developing a virtual laboratory seems highly efficient. In the present study, the numerical results for hydrodynamic coefficients of a high-speed craft are verified against Troesch’s (1992 experimental results. In the following, after determination of hydrodynamic coefficients of a planing catamaran with and without foil, the foil effects on its hydrodynamic coefficients are evaluated. The results indicate that most of the coefficients are frequency independent especially at high frequencies.
Aurora A phosphorylates MCAK to control ran-dependent spindle bipolarity.
Zhang, Xin; Ems-McClung, Stephanie C; Walczak, Claire E
2008-07-01
During mitosis, mitotic centromere-associated kinesin (MCAK) localizes to chromatin/kinetochores, a cytoplasmic pool, and spindle poles. Its localization and activity in the chromatin region are regulated by Aurora B kinase; however, how the cytoplasmic- and pole-localized MCAK are regulated is currently not clear. In this study, we used Xenopus egg extracts to form spindles in the absence of chromatin and centrosomes and found that MCAK localization and activity are tightly regulated by Aurora A. This regulation is important to focus microtubules at aster centers and to facilitate the transition from asters to bipolar spindles. In particular, we found that MCAK colocalized with NuMA and XMAP215 at the center of Ran asters where its activity is regulated by Aurora A-dependent phosphorylation of S196, which contributes to proper pole focusing. In addition, we found that MCAK localization at spindle poles was regulated through another Aurora A phosphorylation site (S719), which positively enhances bipolar spindle formation. This is the first study that clearly defines a role for MCAK at the spindle poles as well as identifies another key Aurora A substrate that contributes to spindle bipolarity.
Directory of Open Access Journals (Sweden)
Qilin Tian
2016-06-01
Full Text Available Ras-related guanosine triphosphate (GTP-binding nuclear protein (Ran GTPases function as molecular switches and regulate diverse cellular events in eukaryotes. Our previous work suggested that DlRan3B is active during longan (Dimocarpus longan Lour. somatic embryogenesis (SE processes. Herein, subcellular localization of DlRan3B was found to be localized in the nucleus and expression profiling of DlRan3B was performed during longan SE and after exposure to plant hormones (indoleacetic acid (IAA, gibberellin A3 (GA3, salicylic acid (SA, methyl jasmonte (MeJA, and abscisic acid (ABA. We cloned and sequenced 1569 bp of 5′-flanking sequence of DlRan3B (GenBank: JQ279697. Bioinformatic analysis indicated that the promoter contained plant hormone-related regulatory elements. Deletion analysis and responses to hormones identified stimulative and repressive regulatory elements in the DlRan3B promoter. The key elements included those responding to auxin, gibberellin, SA, MeJA, and ABA. DlRan3B was located in the nucleus and accumulated in the late stage of longan SE. The expression of DlRan3B was significantly induced by IAA, GA3, and ABA, but suppressed by SA and MeJA. Promoter transcription was induced by IAA and GA3, but suppressed by SA. Thus, DlRan3B might participate in auxin, gibberellin, and ABA responses during longan late SE, and DlRan3B is involved in phytohormone responsiveness.
Large Eddy Simulation of Engineering Flows: A Bill Reynolds Legacy.
Moin, Parviz
2004-11-01
The term, Large eddy simulation, LES, was coined by Bill Reynolds, thirty years ago when he and his colleagues pioneered the introduction of LES in the engineering community. Bill's legacy in LES features his insistence on having a proper mathematical definition of the large scale field independent of the numerical method used, and his vision for using numerical simulation output as data for research in turbulence physics and modeling, just as one would think of using experimental data. However, as an engineer, Bill was pre-dominantly interested in the predictive capability of computational fluid dynamics and in particular LES. In this talk I will present the state of the art in large eddy simulation of complex engineering flows. Most of this technology has been developed in the Department of Energy's ASCI Program at Stanford which was led by Bill in the last years of his distinguished career. At the core of this technology is a fully implicit non-dissipative LES code which uses unstructured grids with arbitrary elements. A hybrid Eulerian/ Largangian approach is used for multi-phase flows, and chemical reactions are introduced through dynamic equations for mixture fraction and reaction progress variable in conjunction with flamelet tables. The predictive capability of LES is demonstrated in several validation studies in flows with complex physics and complex geometry including flow in the combustor of a modern aircraft engine. LES in such a complex application is only possible through efficient utilization of modern parallel super-computers which was recognized and emphasized by Bill from the beginning. The presentation will include a brief mention of computer science efforts for efficient implementation of LES.
The Penguin: a Low Reynolds Number Powered Glider for Station Keeping Missions
Costello, J. K.; Greene, D. W.; Lee, T. T.; Matier, P. T.; Mccarthy, T. R.; Mcguire, R. J.; Schuette, M. J.
1990-01-01
The Penguin is a low Reynolds number (approx. 100,000) remotely piloted vehicle (RPV). It was designed to fly three laps indoors around two pylons in a figure-eight course while maximizing loiter time. The Penguin's low Reynolds number mission is an important one currently being studied for possible future flights in the atmospheres of other planets and for specialized military missions. Although the Penguin's mission seemed quite simple at first, the challenges of such low Reynolds number flight have proven to be quite unique. In addition to the constraint of low Reynolds number flight, the aircraft had to be robust in its control, highly durable, and it had to carry a small instrument package. The Penguin's flight plan, concept, performance, aerodynamic design, weight estimation, structural design, propulsion, stability and control, and cost estimate is detailed.
Improvement of Reynolds-Stress and Triple-Product Lag Models
Olsen, Michael E.; Lillard, Randolph P.
2017-01-01
The Reynolds-stress and triple product Lag models were created with a normal stress distribution which was denied by a 4:3:2 distribution of streamwise, spanwise and wall normal stresses, and a ratio of r(sub w) = 0.3k in the log layer region of high Reynolds number flat plate flow, which implies R11(+)= [4/(9/2)*.3] approximately 2.96. More recent measurements show a more complex picture of the log layer region at high Reynolds numbers. The first cut at improving these models along with the direction for future refinements is described. Comparison with recent high Reynolds number data shows areas where further work is needed, but also shows inclusion of the modeled turbulent transport terms improve the prediction where they influence the solution. Additional work is needed to make the model better match experiment, but there is significant improvement in many of the details of the log layer behavior.
Turbulent Transport at High Reynolds Numbers in an Inertial Confinement Fusion Context
2014-09-01
ABSTRACT Turbulent Transport at High Reynolds Numbers in an Inertial Confinement Fusion Context Report Title Mix is a critical input to hydro... inertial confinement fusion (ICF) targets. Mix contributes to numerical solution uncertainty through its dependence on turbulent transport coefficients...lanl.gov Turbulent Transport at High Reynolds Numbers in an Inertial Confinement Fusion Context Mix is a critical input to hydro simulations used in
2016-06-23
with implications in flame diagnostics. Applied Physics B., 104:689–698, 2011. 22 DISTRIBUTION A: Distribution approved for public release Participating...AFRL-AFOSR-VA-TR-2016-0277 Experimental Investigation of Turbulence- Chemistry Interaction in High-Reynolds-Number Turbulent Partially Premixed...4. TITLE AND SUBTITLE [U] Experimental investigation of turbulence- chemistry interaction in high-Reynolds-number 5a. CONTRACT NUMBER turbulent
Kim, S. H.; Arnold, D.; Lloyd, A.; Roux, S. J.
2001-01-01
We cloned a cDNA encoding an Arabidopsis Ran binding protein, AtRanBP1c, and generated transgenic Arabidopsis expressing the antisense strand of the AtRanBP1c gene to understand the in vivo functions of the Ran/RanBP signal pathway. The transgenic plants showed enhanced primary root growth but suppressed growth of lateral roots. Auxin significantly increased lateral root initiation and inhibited primary root growth in the transformants at 10 pM, several orders of magnitude lower than required to induce these responses in wild-type roots. This induction was followed by a blockage of mitosis in both newly emerged lateral roots and in the primary root, ultimately resulting in the selective death of cells in the tips of both lateral and primary roots. Given the established role of Ran binding proteins in the transport of proteins into the nucleus, these findings are consistent with a model in which AtRanBP1c plays a key role in the nuclear delivery of proteins that suppress auxin action and that regulate mitotic progress in root tips.
Influence of Reynolds Number on Multi-Objective Aerodynamic Design of a Wind Turbine Blade
Ge, Mingwei; Fang, Le; Tian, De
2015-01-01
At present, the radius of wind turbine rotors ranges from several meters to one hundred meters, or even more, which extends Reynolds number of the airfoil profile from the order of 105 to 107. Taking the blade for 3MW wind turbines as an example, the influence of Reynolds number on the aerodynamic design of a wind turbine blade is studied. To make the study more general, two kinds of multi-objective optimization are involved: one is based on the maximum power coefficient (CPopt) and the ultimate load, and the other is based on the ultimate load and the annual energy production (AEP). It is found that under the same configuration, the optimal design has a larger CPopt or AEP (CPopt//AEP) for the same ultimate load, or a smaller load for the same CPopt//AEP at higher Reynolds number. At a certain tip-speed ratio or ultimate load, the blade operating at higher Reynolds number should have a larger chord length and twist angle for the maximum Cpopt//AEP. If a wind turbine blade is designed by using an airfoil database with a mismatched Reynolds number from the actual one, both the load and Cpopt//AEP will be incorrectly estimated to some extent. In some cases, the assessment error attributed to Reynolds number is quite significant, which may bring unexpected risks to the earnings and safety of a wind power project. PMID:26528815
Influence of Reynolds Number on Multi-Objective Aerodynamic Design of a Wind Turbine Blade.
Ge, Mingwei; Fang, Le; Tian, De
2015-01-01
At present, the radius of wind turbine rotors ranges from several meters to one hundred meters, or even more, which extends Reynolds number of the airfoil profile from the order of 105 to 107. Taking the blade for 3MW wind turbines as an example, the influence of Reynolds number on the aerodynamic design of a wind turbine blade is studied. To make the study more general, two kinds of multi-objective optimization are involved: one is based on the maximum power coefficient (CPopt) and the ultimate load, and the other is based on the ultimate load and the annual energy production (AEP). It is found that under the same configuration, the optimal design has a larger CPopt or AEP (CPopt//AEP) for the same ultimate load, or a smaller load for the same CPopt//AEP at higher Reynolds number. At a certain tip-speed ratio or ultimate load, the blade operating at higher Reynolds number should have a larger chord length and twist angle for the maximum Cpopt//AEP. If a wind turbine blade is designed by using an airfoil database with a mismatched Reynolds number from the actual one, both the load and Cpopt//AEP will be incorrectly estimated to some extent. In some cases, the assessment error attributed to Reynolds number is quite significant, which may bring unexpected risks to the earnings and safety of a wind power project.
The cyst nematode SPRYSEC protein RBP-1 elicits Gpa2- and RanGAP2-dependent plant cell death.
Directory of Open Access Journals (Sweden)
Melanie Ann Sacco
2009-08-01
Full Text Available Plant NB-LRR proteins confer robust protection against microbes and metazoan parasites by recognizing pathogen-derived avirulence (Avr proteins that are delivered to the host cytoplasm. Microbial Avr proteins usually function as virulence factors in compatible interactions; however, little is known about the types of metazoan proteins recognized by NB-LRR proteins and their relationship with virulence. In this report, we demonstrate that the secreted protein RBP-1 from the potato cyst nematode Globodera pallida elicits defense responses, including cell death typical of a hypersensitive response (HR, through the NB-LRR protein Gpa2. Gp-Rbp-1 variants from G. pallida populations both virulent and avirulent to Gpa2 demonstrated a high degree of polymorphism, with positive selection detected at numerous sites. All Gp-RBP-1 protein variants from an avirulent population were recognized by Gpa2, whereas virulent populations possessed Gp-RBP-1 protein variants both recognized and non-recognized by Gpa2. Recognition of Gp-RBP-1 by Gpa2 correlated to a single amino acid polymorphism at position 187 in the Gp-RBP-1 SPRY domain. Gp-RBP-1 expressed from Potato virus X elicited Gpa2-mediated defenses that required Ran GTPase-activating protein 2 (RanGAP2, a protein known to interact with the Gpa2 N terminus. Tethering RanGAP2 and Gp-RBP-1 variants via fusion proteins resulted in an enhancement of Gpa2-mediated responses. However, activation of Gpa2 was still dependent on the recognition specificity conferred by amino acid 187 and the Gpa2 LRR domain. These results suggest a two-tiered process wherein RanGAP2 mediates an initial interaction with pathogen-delivered Gp-RBP-1 proteins but where the Gpa2 LRR determines which of these interactions will be productive.
Sex Effect on Average Bioequivalence.
Ibarra, Manuel; Vázquez, Marta; Fagiolino, Pietro
2017-01-01
Generic formulations are by far the most prescribed drugs. This scenario is highly beneficial for society because medication expenses are significantly reduced after expiration of the exclusivity period conceded to the branded name drug. Correspondingly, these formulations must be adequately evaluated to avoid drug inefficacy and toxicity in the overall patient population. Bioequivalence studies are the only in vivo evaluation that a generic drug must overcome to reach the market. These clinical trials have not been exempt from underrepresentation of female subjects and a lack of sex-based analysis. Frequently, conclusions obtained in men are extrapolated to women. Furthermore, the obtained results are not analyzed to determine sex differences. The aim of this study was to discuss the effect that male and female differences in gastrointestinal physiology can have on bioequivalence conclusions and to show why a sex-based analysis must be conducted in these studies to improve the evaluation of generic drugs. This discussion was based on observed sex differences in product bioavailability discrimination (sex-by-formulation interaction) and on residual variability through an analysis of average bioequivalence data previously reported by other researchers and data collected by our center. Bioequivalence studies of oral formulations, with a 2-period, 2-sequence, 2-treatment random crossover design performed in healthy subjects with at least 6 subjects of each sex, were included. In addition, the bioequivalence conclusion that would have been reached in each study if performed with only 1 sex was estimated. The data reveal that differences in both product bioavailability discrimination and residual variability occur with a significant incidence in bioequivalence studies. In either Cmax or AUC, a significant sex-by-formulation interaction was present in 1 of 3 reviewed studies, whereas differences in residual variability between sexes were significant for >50% of studies
Kim, Dong-Hyun; Kwon, Sanghoon; Byun, Sangwon; Xiao, Zhen; Park, Sean; Wu, Shwu-Yuan; Chiang, Cheng-Ming; Kemper, Byron; Kemper, Jongsook Kim
2016-01-01
Bile acids (BAs) are recently recognized signalling molecules that profoundly affect metabolism. Because of detergent-like toxicity, BA levels must be tightly regulated. An orphan nuclear receptor, Small Heterodimer Partner (SHP), plays a key role in this regulation, but how SHP senses the BA signal for feedback transcriptional responses is not clearly understood. We show an unexpected function of a nucleoporin, RanBP2, in maintaining BA homoeostasis through SUMOylation of SHP. Upon BA signalling, RanBP2 co-localizes with SHP at the nuclear envelope region and mediates SUMO2 modification at K68, which facilitates nuclear transport of SHP and its interaction with repressive histone modifiers to inhibit BA synthetic genes. Mice expressing a SUMO-defective K68R SHP mutant have increased liver BA levels, and upon BA- or drug-induced biliary insults, these mice exhibit exacerbated cholestatic pathologies. These results demonstrate a function of RanBP2-mediated SUMOylation of SHP in maintaining BA homoeostasis and protecting from the BA hepatotoxicity. PMID:27412403
Lin, Tsung-Yao; Chen, Ku-Chung; Liu, Hsing-Jin Eugene; Liu, Ann-Jeng; Wang, Kun-Li; Shih, Chwen-Ming
2016-01-01
Chronic myeloid leukemia (CML) is a myeloproliferative disease. Imatinib (IM), the first line treatment for CML, is excessively expensive and induces various side effects in CML patients. Therefore, it is essential to investigate a new strategy for improving CML therapy. Our immunoblot data revealed that RanGTPase activating protein 1 (RanGAP1) protein levels increased by approximately 30-fold in K562 cells compared with those in normal cells. RanGAP1 is one of the important components of RanGTPase system, which regulates the export of nuclear protein. However, whether RanGAP1 level variation influences BCR-ABL nuclear export is still unknown. In this report, using shRNA to downregulate RanGAP1 expression level augmented K562 cell apoptosis by approximately 40% after treatment with 250 nM IM. Immunofluorescence assay also indicated that three-fold of nuclear BCR-ABL was detected. These data suggest that BCR-ABL nuclear entrapment induced by RanGAP1 downregulation can be used to improve IM efficacy. Moreover, our qRT-PCR data indicated a trend of inverse correlation between the RanGAP1 and microRNA (miR)-1301 levels in CML patients. MiR-1301, targeting the RanGAP1 3' untranslated region, decreased by approximately 100-fold in K562 cells compared with that in normal cells. RanGAP1 downregulation by miR-1301 transfection impairs BCR-ABL nuclear export to increase approximately 60% of cell death after treatment of 250 nM IM. This result was almost the same as treatment with 1000 nM IM alone. Furthermore, immunofluorescence assay demonstrated that Tyr-99 of nuclear P73 was phosphorylated accompanied with nuclear entrapment of BCR-ABL after transfection with RanGAP1 shRNA or miR-1301 in IM-treated K562 cells. Altogether, we demonstrated that RanGAP1 downregulation can mediate BCR-ABL nuclear entrapment to activate P73-dependent apoptosis pathway which is a novel strategy for improving current IM treatment for CML.
Derakhti, Morteza; Kirby, James T.; Shi, Fengyan; Ma, Gangfeng
2016-11-01
Field-scale modeling of wave-breaking-induced turbulence and mean circulation is still challenging. Although Boussinesq-type models have been successfully used to study field-scale wave transformation and wave-breaking-driven circulation, they cannot provide turbulence or the vertical structure of the velocity field. In addition, the applicability of such models is limited to shallow water. In Part 1 (Derakhti et al., 2016b) of this study, we showed that the non-hydrostatic σ-coordinate RANS model NHWAVE, as described by Derakhti et al. (2016a), accurately predicts organized wave motions and total wave-breaking-induced energy dissipation from deep-water up to the swash zone using a few vertical σ-layers. In this paper, our goal is to examine what level of detail of wave-breaking-induced turbulence and mean circulation, both in depth- and steepness-limited breaking waves, can be reproduced by NHWAVE. Further, effects of modeled turbulent eddy viscosity on the predicted time-averaged velocity distribution is discussed. We establish that NHWAVE is capable of predicting the structure of the mean velocity and vorticity fields including large-scale breaking-induced coherent vortices in deep-water breaking events; where the absence of turbulence-induced eddy viscosity results in the overprediction of the velocity and vorticity field in the breaking region. We show that NHWAVE reduces the required CPU time up to two orders of magnitude in comparison with a comparable VOF-based simulation.
Site Averaged Neutron Soil Moisture: 1988 (Betts)
National Aeronautics and Space Administration — ABSTRACT: Site averaged product of the neutron probe soil moisture collected during the 1987-1989 FIFE experiment. Samples were averaged for each site, then averaged...
Site Averaged Gravimetric Soil Moisture: 1989 (Betts)
National Aeronautics and Space Administration — Site averaged product of the gravimetric soil moisture collected during the 1987-1989 FIFE experiment. Samples were averaged for each site, then averaged for each...
Site Averaged Gravimetric Soil Moisture: 1988 (Betts)
National Aeronautics and Space Administration — Site averaged product of the gravimetric soil moisture collected during the 1987-1989 FIFE experiment. Samples were averaged for each site, then averaged for each...
Site Averaged Gravimetric Soil Moisture: 1987 (Betts)
National Aeronautics and Space Administration — ABSTRACT: Site averaged product of the gravimetric soil moisture collected during the 1987-1989 FIFE experiment. Samples were averaged for each site, then averaged...
Site Averaged Gravimetric Soil Moisture: 1987 (Betts)
National Aeronautics and Space Administration — Site averaged product of the gravimetric soil moisture collected during the 1987-1989 FIFE experiment. Samples were averaged for each site, then averaged for each...
Reynolds and froude number effect on the flow past an interface-piercing circular cylinder
Directory of Open Access Journals (Sweden)
Bonguk Koo
2014-09-01
Full Text Available The two-phase turbulent flow past an interface-piercing circular cylinder is studied using a high-fidelity orthogonal curvilinear grid solver with a Lagrangian dynamic subgrid-scale model for large-eddy simulation and a coupled level set and volume of fluid method for air-water interface tracking. The simulations cover the sub-critical and critical and post critical regimes of the Reynolds and sub and super-critical Froude numbers in order to investigate the effect of both dimensionless parameters on the flow. Significant changes in flow features near the air-water interface were observed as the Reynolds number was increased from the sub-critical to the critical regime. The interface makes the separation point near the interface much delayed for all Reynolds numbers. The separation region at intermediate depths is remarkably reduced for the critical Reynolds number regime. The deep flow resembles the single-phase turbulent flow past a circular cylinder, but includes the effect of the free-surface and the limited span length for sub-critical Reynolds numbers. At different Froude numbers, the air-water interface exhibits significantly changed structures, including breaking bow waves with splashes and bubbles at high Froude numbers. Instantaneous and mean flow features such as interface structures, vortex shedding, Reynolds stresses, and vorticity transport are also analyzed. The results are compared with reference experimental data available in the literature. The deep flow is also compared with the single-phase turbulent flow past a circular cylinder in the similar ranges of Reynolds numbers. Discussion is provided concerning the limitations of the current simulations and available experimental data along with future research.
Reynolds and froude number effect on the flow past an interface-piercing circular cylinder
Directory of Open Access Journals (Sweden)
Koo Bonguk
2014-09-01
Full Text Available The two-phase turbulent flow past an interface-piercing circular cylinder is studied using a high-fidelity orthogonal curvilinear grid solver with a Lagrangian dynamic subgrid-scale model for large-eddy simulation and a coupled level set and volume of fluid method for air-water interface tracking. The simulations cover the sub-critical and critical and post critical regimes of the Reynolds and sub and super-critical Froude numbers in order to investigate the effect of both dimensionless parameters on the flow. Significant changes in flow features near the air-water interface were observed as the Reynolds number was increased from the sub-critical to the critical regime. The interface makes the separation point near the interface much delayed for all Reynolds numbers. The separation region at intermediate depths is remarkably reduced for the critical Reynolds number regime. The deep flow resembles the single-phase turbulent flow past a circular cylinder, but includes the effect of the free-surface and the limited span length for sub-critical Reynolds numbers. At different Froude numbers, the air-water interface exhibits significantly changed structures, including breaking bow waves with splashes and bubbles at high Froude numbers. Instantaneous and mean flow features such as interface structures, vortex shedding, Reynolds stresses, and vorticity transport are also analyzed. The results are compared with reference experimental data available in the literature. The deep flow is also compared with the single-phase turbulent flow past a circular cylinder in the similar ranges of Reynolds numbers. Discussion is provided concerning the limitations of the current simulations and available experimental data along with future research
Energy Technology Data Exchange (ETDEWEB)
Sigg, K. C.; Coffield, R. D.
2002-09-01
High Reynolds number test data has recently been reported for both single and multiple piping elbow design configurations at earlier ASME Fluid Engineering Division conferences. The data of these studies ranged up to a Reynolds number of 42 x 10[sup]6 which is significantly greater than that used to establish design correlations before the data was available. Many of the accepted design correlations, based on the lower Reynolds number data, date back as much as fifty years. The new data shows that these earlier correlations are extremely conservative for high Reynolds number applications. Based on the recent high Reynolds number information a new recommended method has been developed for calculating irrecoverable pressure loses in piping systems for design considerations such as establishing pump sizing requirements. This paper describes the recommended design approach and additional testing that has been performed as part of the qualification of the method. This qualification testing determined the irrecoverable pressure loss of a piping configuration that would typify a limiting piping section in a complicated piping network, i.e., multiple, tightly coupled, out-of-plane elbows in series under high Reynolds number flow conditions. The overall pressure loss measurements were then compared to predictions, which used the new methodology to assure that conservative estimates for the pressure loss (of the type used for pump sizing) were obtained. The recommended design methodology, the qualification testing and the comparison between the predictions and the test data are presented. A major conclusion of this study is that the recommended method for calculating irrecoverable pressure loss in piping systems is conservative yet significantly lower than predicted by early design correlations that were based on the extrapolation of low Reynolds number test data.
Energy Technology Data Exchange (ETDEWEB)
Lee, Seung Jun; Park, Ik Kyu; Yoon, Han Young [Thermal-Hydraulic Safety Research Division, Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Jae, Byoung [School of Mechanical Engineering, Chungnam National University, Daejeon (Korea, Republic of)
2017-01-15
Two-fluid equations are widely used to obtain averaged behaviors of two-phase flows. This study addresses a problem that may arise when the two-fluid equations are used for multi-dimensional bubbly flows. If steady drag is the only accounted force for the interfacial momentum transfer, the disperse-phase velocity would be the same as the continuous-phase velocity when the flow is fully developed without gravity. However, existing momentum equations may show unphysical results in estimating the relative velocity of the disperse phase against the continuous-phase. First, we examine two types of existing momentum equations. One is the standard two-fluid momentum equation in which the disperse-phase is treated as a continuum. The other is the averaged momentum equation derived from a solid/ fluid particle motion. We show that the existing equations are not proper for multi-dimensional bubbly flows. To resolve the problem mentioned above, we modify the form of the Reynolds stress terms in the averaged momentum equation based on the solid/fluid particle motion. The proposed equation shows physically correct results for both multi-dimensional laminar and turbulent flows.
National Research Council Canada - National Science Library
Shawn C Chafe; Jacqueline B Pierce; Dev Mangroo
2012-01-01
.... Treatment of mammalian cells with polysorbitan monolaurate was found to inhibit nuclear export of tRNA and proteins, which are processes dependent on RanGTP in the nucleus, but not nuclear import...
Palavicini, Juan Pablo; Wang, Hongjie; Minond, Dmitriy; Bianchi, Elisabetta; Xu, Shaohua; Lakshmana, Madepalli K
2014-01-01
Loss of synaptic proteins and functional synapses in the brains of patients with Alzheimer's disease (AD) as well as transgenic mouse models expressing amyloid-β protein precursor is now well established. However, the earliest age at which such loss of synapses occurs, and whether known markers of AD progression accelerate functional deficits is completely unknown. We previously showed that RanBP9 overexpression leads to enhanced amyloid plaque burden in a mouse model of AD. In this study, we found significant reductions in the levels of synaptophysin and spinophilin, compared with wild-type controls, in both the cortex and the hippocampus of 5- and 6-month old but not 3- or 4-month old APΔE9/RanBP9 triple transgenic mice, and not in APΔE9 double transgenic mice, nor in RanBP9 single transgenic mice. Interestingly, amyloid plaque burden was also increased in the APΔE9/RanBP9 mice at 5-6 months. Consistent with these results, we found significant deficits in learning and memory in the APΔE9/RanBP9 mice at 5 and 6 month. These data suggest that increased amyloid plaques and accelerated learning and memory deficits and loss of synaptic proteins induced by RanBP9 are correlated. Most importantly, APΔE9/RanBP9 mice also showed significantly reduced levels of the phosphorylated form of cofilin in the hippocampus. Taken together these data suggest that RanBP9 overexpression down-regulates cofilin, causes early synaptic deficits and impaired learning, and accelerates accumulation of amyloid plaques in the mouse brain.
Klewicki, J. C.; Chini, G. P.; Gibson, J. F.
2017-03-01
Recent and on-going advances in mathematical methods and analysis techniques, coupled with the experimental and computational capacity to capture detailed flow structure at increasingly large Reynolds numbers, afford an unprecedented opportunity to develop realistic models of high Reynolds number turbulent wall-flow dynamics. A distinctive attribute of this new generation of models is their grounding in the Navier-Stokes equations. By adhering to this challenging constraint, high-fidelity models ultimately can be developed that not only predict flow properties at high Reynolds numbers, but that possess a mathematical structure that faithfully captures the underlying flow physics. These first-principles models are needed, for example, to reliably manipulate flow behaviours at extreme Reynolds numbers. This theme issue of Philosophical Transactions of the Royal Society A provides a selection of contributions from the community of researchers who are working towards the development of such models. Broadly speaking, the research topics represented herein report on dynamical structure, mechanisms and transport; scale interactions and self-similarity; model reductions that restrict nonlinear interactions; and modern asymptotic theories. In this prospectus, the challenges associated with modelling turbulent wall-flows at large Reynolds numbers are briefly outlined, and the connections between the contributing papers are highlighted.
Direct Numerical Simulation of Flows over an NACA-0012 Airfoil at Low and Moderate Reynolds Numbers
Balakumar, P.
2017-01-01
Direct numerical simulations (DNS) of flow over an NACA-0012 airfoil are performed at a low and a moderate Reynolds numbers of Re(sub c)=50 times10(exp 3) and 1times 10(exp 6). The angles of attack are 5 and 15 degrees at the low and the moderate Reynolds number cases respectively. The three-dimensional unsteady compressible Navier-Stokes equations are solved using higher order compact schemes. The flow field in the low Reynolds number case consists of a long separation bubble near the leading-edge region and an attached boundary layer on the aft part of the airfoil. The shear layer that formed in the separated region persisted up to the end of the airfoil. The roles of the turbulent diffusion, advection, and dissipation terms in the turbulent kinetic-energy balance equation change as the boundary layer evolves over the airfoil. In the higher Reynolds number case, the leading-edge separation bubble is very small in length and in height. A fully developed turbulent boundary layer is observed in a short distance downstream of the reattachment point. The boundary layer velocity near the wall gradually decreases along the airfoil. Eventually, the boundary layer separates near the trailing edge. The Reynolds stresses peak in the outer part of the boundary layer and the maximum amplitude also gradually increases along the chord.
Reynolds number effects on scale energy analysis of turbulent boundary layers
Saikrishnan, Neelakantan; Longmire, Ellen; Marusic, Ivan
2009-11-01
Scale energy analysis combines two approaches of studying wall- bounded turbulent flows - analysis in physical space and analysis in scale space. Previously, scale energy analysis has been performed on DNS channel flow data for a range of friction Reynolds numbers Reτ= 180-934 and dual plane PIV boundary layer data at Reτ= 1100. The dual plane technique allows determination of the full velocity gradient tensor in the measurement plane. Dual Plane PIV data were acquired in streamwise-spanwise planes in the logarithmic region of a water channel boundary layer at two higher Reynolds numbers - Reτ= 2400 and 3000. The results of this study will be described and compared with the lower Re data. It is observed that in general, the production and scale transfer terms of the turbulent kinetic energy increase with increasing Reynolds number. The cross-over scale, which divides the range of scales into a transfer-dominated region and a production- dominated region, increases with increasing Reynolds numbers, resulting in a larger range of transfer-dominated scales at higher Reynolds numbers.
NUMERICAL INVESTIGATION OF TWO ELEMENT CAMBER MORPHING AIRFOIL IN LOW REYNOLDS NUMBER FLOWS
Directory of Open Access Journals (Sweden)
RAJESH SENTHIL KUMAR T.
2017-07-01
Full Text Available Aerodynamic performance of a two-element camber morphing airfoil was investigated at low Reynolds number using the transient SST model in ANSYS FLUENT 14.0 and eN method in XFLR5. The two-element camber morphing concept was employed to morph the baseline airfoil into another airfoil by altering the orientation of mean-line at 35% of the chord to achieve better aerodynamic efficiency. NACA 0012 was selected as baseline airfoil. NACA 23012 was chosen as the test case as it has the camber-line similar to that of the morphed airfoil and as it has the same thickness as that of the baseline airfoil. The simulations were carried out at chord based Reynolds numbers of 2.5×105 and 3.9×105. The aerodynamic force coefficients, aerodynamic efficiency and the location of the transition point of laminar separation bubble over these airfoils were studied for various angles of attack. It was found that the aerodynamic efficiency of the morphed airfoil was 12% higher than that of the target airfoil at 4° angle of attack for Reynolds number of 3.9×105 and 54% rise in aerodynamic performance was noted as Reynolds number was varied from 2.5×105 to 3.9×105. The morphed airfoil exhibited the nature of low Reynolds number airfoil.
Numerical Simulations of Subscale Wind Turbine Rotor Inboard Airfoils at Low Reynolds Number
Energy Technology Data Exchange (ETDEWEB)
Blaylock, Myra L. [Sandia National Lab. (SNL-CA), Livermore, CA (United States). Thermal/ Fluid Sciences & Engineering Dept.; Maniaci, David Charles [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Wind Energy Technologies Dept.; Resor, Brian R. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Wind Energy Technologies Dept.
2015-04-01
New blade designs are planned to support future research campaigns at the SWiFT facility in Lubbock, Texas. The sub-scale blades will reproduce specific aerodynamic characteristics of utility-scale rotors. Reynolds numbers for megawatt-, utility-scale rotors are generally above 2-8 million. The thickness of inboard airfoils for these large rotors are typically as high as 35-40%. The thickness and the proximity to three-dimensional flow of these airfoils present design and analysis challenges, even at the full scale. However, more than a decade of experience with the airfoils in numerical simulation, in the wind tunnel, and in the field has generated confidence in their performance. Reynolds number regimes for the sub-scale rotor are significantly lower for the inboard blade, ranging from 0.7 to 1 million. Performance of the thick airfoils in this regime is uncertain because of the lack of wind tunnel data and the inherent challenge associated with numerical simulations. This report documents efforts to determine the most capable analysis tools to support these simulations in an effort to improve understanding of the aerodynamic properties of thick airfoils in this Reynolds number regime. Numerical results from various codes of four airfoils are verified against previously published wind tunnel results where data at those Reynolds numbers are available. Results are then computed for other Reynolds numbers of interest.
Carstedt, Göran
2008-01-01
Juhtimiskonsultant ning Organisatsioonilise Õppimise Ühingu eestvedaja ja arendaja Göran Carsedt vastab küsimustele, mis puudutavad ettevõtte tegevust personali tööle pühendumise parendamiseks, ettevõtte jätkusuutlikku juhtimist ja tootlikkust, majanduslanguse mõju ettevõtete personalipoliitikale, talendijuhtimist, väikeste ettevõttete ellujäämist majanduslanguse ajal, IKEA kui hea tööandja mainet ning jätkusuutlikku personaliarendajat. Lisa: Jätkusuutlik juhtimine Rootsi moodi
Patil, Hemangi; Saha, Arjun; Senda, Eugene; Cho, Kyoung-in; Haque, MdEmdadul; Yu, Minzhong; Qiu, Sunny; Yoon, Dosuk; Hao, Ying; Peachey, Neal S.; Ferreira, Paulo A.
2014-01-01
Retinal pigment epithelium (RPE) degeneration underpins diseases triggered by disparate genetic lesions, noxious insults, or both. The pleiotropic Ranbp2 controls the expression of intrinsic and extrinsic pathological stressors impinging on cellular viability. However, the physiological targets and mechanisms controlled by Ranbp2 in tissue homeostasis, such as RPE, are ill defined. We show that mice, RPE-cre::Ranbp2−/−, with selective Ranbp2 ablation in RPE develop pigmentary changes, syncytia, hypoplasia, age-dependent centrifugal and non-apoptotic degeneration of the RPE, and secondary leakage of choriocapillaris. These manifestations are accompanied by the development of F-actin clouds, metalloproteinase-11 activation, deregulation of expression or subcellular localization of critical RPE proteins, atrophic cell extrusions into the subretinal space, and compensatory proliferation of peripheral RPE. To gain mechanistic insights into what Ranbp2 activities are vital to the RPE, we performed genetic complementation analyses of transgenic lines of bacterial artificial chromosomes of Ranbp2 harboring loss of function of selective Ranbp2 domains expressed in a Ranbp2−/− background. Among the transgenic lines produced, only TgRBD2/3*-HA::RPE-cre::Ranbp2−/−-expressing mutations, which selectively impair binding of RBD2/3 (Ran-binding domains 2 and 3) of Ranbp2 to Ran-GTP, recapitulate RPE degeneration, as observed with RPE-cre::Ranbp2−/−. By contrast, TgRBD2/3*-HA expression rescues the degeneration of cone photoreceptors lacking Ranbp2. The RPE of RPE-cre::Ranbp2−/− and TgRBD2/3*-HA::RPE-cre::Ranbp2−/− share proteostatic deregulation of Ran GTPase, serotransferrin, and γ-tubulin and suppression of light-evoked electrophysiological responses. These studies unravel selective roles of Ranbp2 and its RBD2 and RBD3 in RPE survival and functions. We posit that the control of Ran GTPase by Ranbp2 emerges as a novel therapeutic target in diseases
Patil, Hemangi; Saha, Arjun; Senda, Eugene; Cho, Kyoung-in; Haque, MdEmdadul; Yu, Minzhong; Qiu, Sunny; Yoon, Dosuk; Hao, Ying; Peachey, Neal S; Ferreira, Paulo A
2014-10-24
Retinal pigment epithelium (RPE) degeneration underpins diseases triggered by disparate genetic lesions, noxious insults, or both. The pleiotropic Ranbp2 controls the expression of intrinsic and extrinsic pathological stressors impinging on cellular viability. However, the physiological targets and mechanisms controlled by Ranbp2 in tissue homeostasis, such as RPE, are ill defined. We show that mice, RPE-cre::Ranbp2(-/-), with selective Ranbp2 ablation in RPE develop pigmentary changes, syncytia, hypoplasia, age-dependent centrifugal and non-apoptotic degeneration of the RPE, and secondary leakage of choriocapillaris. These manifestations are accompanied by the development of F-actin clouds, metalloproteinase-11 activation, deregulation of expression or subcellular localization of critical RPE proteins, atrophic cell extrusions into the subretinal space, and compensatory proliferation of peripheral RPE. To gain mechanistic insights into what Ranbp2 activities are vital to the RPE, we performed genetic complementation analyses of transgenic lines of bacterial artificial chromosomes of Ranbp2 harboring loss of function of selective Ranbp2 domains expressed in a Ranbp2(-/-) background. Among the transgenic lines produced, only Tg(RBD2/3*-HA)::RPE-cre::Ranbp2(-/-)-expressing mutations, which selectively impair binding of RBD2/3 (Ran-binding domains 2 and 3) of Ranbp2 to Ran-GTP, recapitulate RPE degeneration, as observed with RPE-cre::Ranbp2(-/-). By contrast, Tg(RBD2/3*-HA) expression rescues the degeneration of cone photoreceptors lacking Ranbp2. The RPE of RPE-cre::Ranbp2(-/-) and Tg(RBD2/3*-HA)::RPE-cre::Ranbp2(-/-) share proteostatic deregulation of Ran GTPase, serotransferrin, and γ-tubulin and suppression of light-evoked electrophysiological responses. These studies unravel selective roles of Ranbp2 and its RBD2 and RBD3 in RPE survival and functions. We posit that the control of Ran GTPase by Ranbp2 emerges as a novel therapeutic target in diseases promoting
Energy Technology Data Exchange (ETDEWEB)
Park, Su Hyun; Park, Tae Jun; Lim, In Kyoung, E-mail: iklim@ajou.ac.kr
2011-04-15
We have previously reported that G-actin accumulation in nuclei is a universal phenomenon of cellular senescence. By employing primary culture of human diploid fibroblast (HDF) and stress-induced premature senescence (SIPS), we explored whether the failure of actin export to cytoplasm is responsible for actin accumulation in nuclei of senescent cells. Expression of exportin 6 (Exp6) and small G-protein, Ran, was significantly reduced in the replicative senescence, but not yet in SIPS, whereas nuclear import of actin by cofilin was already increased in SIPS. After treatment of young HDF cells with H{sub 2}O{sub 2}, rapid reduction of nuclear RanGTP was observed along with cytoplasmic increase of RanGDP. Furthermore, significantly reduced interaction of Exp6 with RanGTP was found by GST-Exp6 pull-down analysis. Failure of RanGTP restoration was accompanied with inhibition of ATP synthesis and NTF2 sequestration in the nuclei along with accordant change of senescence morphology. Indeed, knockdown of Exp6 expression significantly increased actin molecule in the nuclei of young HDF cells. Therefore, actin accumulation in nuclei of senescent cells is most likely due to the failure of RanGTP restoration with ATP deficiency and NTF2 accumulation in nuclei, which result in the decrease of actin export via Exp6 inactivation, in addition to actin import by cofilin activation.
Directory of Open Access Journals (Sweden)
Glenn Hauk
Full Text Available The DEAD-box RNA helicase Ded1, which is essential in yeast and known as DDX3 in humans, shuttles between the nucleus and cytoplasm and takes part in several basic processes including RNA processing and translation. A key interacting partner of Ded1 is the exportin Xpo1, which together with the GTP-bound state of the small GTPase Ran, facilitates unidirectional transport of Ded1 out of the nucleus. Here we demonstrate that Xpo1 and Ran[GTP] together reduce the RNA-stimulated ATPase and helicase activities of Ded1. Binding and inhibition of Ded1 by Xpo1 depend on the affinity of the Ded1 nuclear export sequence (NES for Xpo1 and the presence of Ran[GTP]. Association with Xpo1/Ran[GTP] reduces RNA-stimulated ATPase activity of Ded1 by increasing the apparent KM for the RNA substrate. Despite the increased KM, the Ded1:Xpo1:Ran[GTP] ternary complex retains the ability to bind single stranded RNA, suggesting that Xpo1/Ran[GTP] may modulate the substrate specificity of Ded1. These results demonstrate that, in addition to transport, exportins such as Xpo1 also have the capability to alter enzymatic activities of their cargo.
Kim, Kyoungyoun; Sureshkumar, Radhakrishna
2013-06-01
To study the influence of dynamic interactions between turbulent vortical structures and polymer stress on turbulent friction drag reduction, a series of simulations of channel flow is performed. We obtain self-consistent evolution of an initial eddy in the presence of polymer stresses by utilizing the finitely extensible nonlinear elastic-Peterlin (FENE-P) model. The initial eddy is extracted by the conditional averages for the second quadrant event from fully turbulent Newtonian flow, and the initial polymer conformation fields are given by the solutions of the FENE-P model equations corresponding to the mean shear flow in the Newtonian case. At a relatively low Weissenberg number We(τ) (=50), defined as the ratio of the polymer relaxation time to the wall time scale, the generation of new vortices is inhibited by polymer-induced countertorques. Thus fewer vortices are generated in the buffer layer. However, the head of the primary hairpin is unaffected by the polymer stress. At larger We(τ) values (≥100), the hairpin head becomes weaker and vortex autogeneration and Reynolds stress growth are almost entirely suppressed. The temporal evolution of the vortex strength and polymer torque magnitude reveals that polymer extension by the vortical motion results in a polymer torque that increases in magnitude with time until a maximum value is reached over a time scale comparable to the polymer relaxation time. The polymer torque retards the vortical motion and Reynolds stress production, which in turn weakens flow-induced chain extension and torque itself. An analysis of the vortex time scales reveals that with increasing We(τ), vortical motions associated with a broader range of time scales are affected by the polymer stress. This is qualitatively consistent with Lumley's time criterion for the onset of drag reduction.
Disotell, Kevin J.; Nikoueeyan, Pourya; Naughton, Jonathan W.; Gregory, James W.
2016-05-01
Recognizing the need for global surface measurement techniques to characterize the time-varying, three-dimensional loading encountered on rotating wind turbine blades, fast-responding pressure-sensitive paint (PSP) has been evaluated for resolving unsteady aerodynamic effects in incompressible flow. Results of a study aimed at demonstrating the laser-based, single-shot PSP technique on a low Reynolds number wind turbine airfoil in static and dynamic stall are reported. PSP was applied to the suction side of a Delft DU97-W-300 airfoil (maximum thickness-to-chord ratio of 30 %) at a chord Reynolds number of 225,000 in the University of Wyoming open-return wind tunnel. Static and dynamic stall behaviors are presented using instantaneous and phase-averaged global pressure maps. In particular, a three-dimensional pressure topology driven by a stall cell pattern is detected near the maximum lift condition on the steady airfoil. Trends in the PSP-measured pressure topology on the steady airfoil were confirmed using surface oil visualization. The dynamic stall case was characterized by a sinusoidal pitching motion with mean angle of 15.7°, amplitude of 11.2°, and reduced frequency of 0.106 based on semichord. PSP images were acquired at selected phase positions, capturing the breakdown of nominally two-dimensional flow near lift stall, development of post-stall suction near the trailing edge, and a highly three-dimensional topology as the flow reattaches. Structural patterns in the surface pressure topologies are considered from the analysis of the individual PSP snapshots, enabled by a laser-based excitation system that achieves sufficient signal-to-noise ratio in the single-shot images. The PSP results are found to be in general agreement with observations about the steady and unsteady stall characteristics expected for the airfoil.
Directory of Open Access Journals (Sweden)
Arunkumar H. S.
2018-01-01
Full Text Available The 2-D numerical study is performed to analyses the flow characteristic behind the elliptical structure placed near the wall for three different gap ratios as 0.25, 0.5, and 1.0. Computational domain and model is initially validated with the unbounded flow over a cylinder without considering wall effect for Reynolds number of 3900. For flow over the cylinder with near wall, computational domain is modelled as Blasius profile is the input to the area of interest. At different gap ratios the effect of boundary layer on vortex shedding is studied with Reynolds number of 1440. By applying different turbulent model for analysis, study the variation in the results and suggest the suitable model for the present type of study. It has been observed that the wall effect is predominant in case of the gap ratio of 0.25 as compared to other gap ratios.
Schmidt, Mirko H H; Broll, Rainer; Bruch, Hans-Peter; Bögler, Oliver; Duchrow, Michael
2003-01-01
The proliferation marker pKi-67 ('Ki-67 antigen') is commonly used in clinical and research pathology to detect proliferating cells, as it is only expressed during cell-cycle progression. Despite the fact that this antigen has been known for nearly two decades, there is still no adequate understanding of its function. This study has therefore identified proteins that interact with pKi-67, using a yeast two-hybrid system. A mammalian two-hybrid system and immunoprecipitation studies were used to verify these interactions. Among other cell-cycle regulatory proteins, two binding partners associated with the small GTPase Ran were identified. In addition, DNA-structural and nucleolus-associated proteins binding to pKi-67 were found. Moreover, it was demonstrated that the N-terminal domain of pKi-67 is capable of self-binding to its own repeat region encoded by exon 13. Since RanBP, a protein involved in the transport of macromolecules over the nuclear lamina, was found to be a binding partner, a possible effect of pKi-67 on the localization of cell-cycle regulatory proteins was proposed. To test this hypothesis, a tetracycline-responsive gene expression system was used to induce the pKi-67 fragments previously used for the two-hybrid screens in HeLa cells. Subsequent immunostaining revealed the translocation of cyclin B1 from cytoplasm to nucleoli in response to this expression. It is suggested that pKi-67 is a Ran-associated protein with a role in the disintegration and reformation of the nucleolus and thereby in entry into and exit from the M-phase. Copyright 2002 John Wiley & Sons, Ltd.
Wave-Related Reynolds Number Parameterizations of CO2 and DMS Transfer Velocities
Brumer, Sophia E.; Zappa, Christopher J.; Blomquist, Byron W.; Fairall, Christopher W.; Cifuentes-Lorenzen, Alejandro; Edson, James B.; Brooks, Ian M.; Huebert, Barry J.
2017-10-01
Predicting future climate hinges on our understanding of and ability to quantify air-sea gas transfer. The latter relies on parameterizations of the gas transfer velocity k, which represents physical mass transfer mechanisms and is usually parameterized as a nonlinear function of wind forcing. In an attempt to reduce uncertainties in k, this study explores empirical parameterizations that incorporate both wind speed and sea state dependence via wave-wind and breaking Reynolds numbers, RH and RB. Analysis of concurrent eddy covariance gas transfer and measured wavefield statistics supplemented by wave model hindcasts shows for the first time that wave-related Reynolds numbers collapse four open ocean data sets that have a wind speed dependence of CO2 transfer velocity ranging from lower than quadratic to cubic. Wave-related Reynolds number and wind speed show comparable performance for parametrizing dimethyl sulfide (DMS) which, because of its higher solubility, is less affected by bubble-mediated exchange associated with wave breaking.
Stochastic representation of the Reynolds transport theorem: revisiting large-scale modeling
Harouna, S Kadri
2016-01-01
We explore the potential of a formulation of the Navier-Stokes equations incorporating a random description of the small-scale velocity component. This model, established from a version of the Reynolds transport theorem adapted to a stochastic representation of the flow, gives rise to a large-scale description of the flow dynamics in which emerges an anisotropic subgrid tensor, reminiscent to the Reynolds stress tensor, together with a drift correction due to an inhomogeneous turbulence. The corresponding subgrid model, which depends on the small scales velocity variance, generalizes the Boussinesq eddy viscosity assumption. However, it is not anymore obtained from an analogy with molecular dissipation but ensues rigorously from the random modeling of the flow. This principle allows us to propose several subgrid models defined directly on the resolved flow component. We assess and compare numerically those models on a standard Green-Taylor vortex flow at Reynolds 1600. The numerical simulations, carried out w...
Time-dependent measurements over membrane plates at low Reynolds number
Hubner, James; Scott, Kyle; Timpe, Amory; Ukeiley, Lawrence
2010-11-01
A segment of low Reynolds number aerodynamic research employs biomimetics for optimization of airfoil shapes to micro air vehicle (MAV) flight. Many of these efforts focus on thin, flexible membrane airfoils inspired by small birds, bats and insects. This design approach, mimicking low Reynolds number flyers (Re wing, leading to both advantageous and disadvantageous effects. Identifying and quantifying the nature of the fluid-structure coupling and how this coupling can passively control the flow is the goal of a recently initiated research project by the authors. This talk will present the objectives of the project and initial findings of synchronized flow (hot-wire anemometry) and surface deflection (laser vibrometry) measurements over rigid plates and flexible membranes at incidence to the free stream flow. A range of flow Reynolds numbers are examined, from 10,000 to 50,000, in which vibration initiates and grow with increasing velocity.
Effect of Reynolds number on flow and mass transfer characteristics of a 90 degree elbow
Fujisawa, Nobuyuki; Ikarashi, Yuya; Yamagata, Takayuki; Taguchi, Syoichi
2016-11-01
The flow and mass transfer characteristics of a 90 degree elbow was studied experimentally by using the mass transfer measurement by plaster dissolution method, the surface flow visualization by oil film method and stereo PIV measurement. The experiments are carried out in a water tunnel of a circular pipe of 56mm in diameter with a working fluid of water. The Reynolds number was varied from 30000 to 200000. The experimental result indicated the change of the mass transfer coefficient distribution in the elbow with increasing the Reynolds number. This phenomenon is further examined by the surface flow visualization and measurement of secondary flow pattern in the elbow, and the results showed the suggested change of the secondary flow pattern in the elbow with increasing the Reynolds numbers.
Evaluation of Full Reynolds Stress Turbulence Models in FUN3D
Dudek, Julianne C.; Carlson, Jan-Renee
2017-01-01
Full seven-equation Reynolds stress turbulence models are a relatively new and promising tool for todays aerospace technology challenges. This paper uses two stress-omega full Reynolds stress models to evaluate challenging flows including shock-wave boundary layer interactions, separation and mixing layers. The Wilcox and the SSGLRR full second-moment Reynolds stress models are evaluated for four problems: a transonic two-dimensional diffuser, a supersonic axisymmetric compression corner, a compressible planar shear layer, and a subsonic axisymmetric jet. Simulation results are compared with experimental data and results using the more commonly used Spalart-Allmaras (SA) one-equation and the Menter Shear Stress Transport (SST) two-equation models.
Jintao Liu; Yulin Wu; Leqin Wang
2013-01-01
Pump-turbines were always running at partial condition with the power grid changing. Flow separations and stall phenomena were obvious in the pump-turbine. Most of the RANS turbulence models solved the shear stress by linear difference scheme and isotropic models, so they could not capture all kinds of vortexes in the pump-turbine well. At present, partially-averaged Navier-Stokes (PANS) model has been found to be better than LES in simulating flow regions especially those with less discretiz...
Investigation of CAST-10-2/DOA 2 airfoil in NAE high Reynolds number two-dimensional test facility
Chan, Y. Y.
1989-01-01
A common airfoil model with the CAST 10-2/DOA-2 profile and 228 mm (9 inches) chord length was tested. The tests performed in NAE covered the Mach numbers from 0.3 to 0.8 and Reynolds numbers from 10 to 30 million. The model was tested with transition free and with transition fixed at 5 percent chord for both the upper and the lower surfaces. The data obtained were analyzed for the effects of Reynolds number, transition fixing and Mach number. The role of the boundary layer on the displacement effect, the interaction with the shock wave and the trailing edge separation are examined. The results are summarized as follows: (1) the airfoil performance depends strongly on Reynolds number and transition fixing; (2) with transition fixed, the aerodynamic quantities such as lift, pitching moment and drag show a monotonic variation with Reynolds number; (3) with transition free, the aerodynamic quantities vary less regularly with Reynolds number and a slight parametric dependency is shown. The weak dependency is due to the compensatory effect of the forward shift of the transition position and the thinning of the turbulent boundary layer as Reynolds number increases; (4) the shock Mach number and the shock position are weakly dependent on Reynolds number; and (5) the long extent of the laminar boundary layer at transonic speeds reduces the drag appreciably at low Reynolds numbers. The drag bucket around the design Mach number can be observed below Reynolds number 15 million.
Shyam, Vikram
2010-01-01
A preprocessor for the Computational Fluid Dynamics (CFD) code TURBO has been developed and tested. The preprocessor converts grids produced by GridPro (Program Development Company (PDC)) into a format readable by TURBO and generates the necessary input files associated with the grid. The preprocessor also generates information that enables the user to decide how to allocate the computational load in a multiple block per processor scenario.
Discontinuous Galerkin methodology for Large-Eddy Simulations of wind turbine airfoils
DEFF Research Database (Denmark)
Frére, A.; Sørensen, Niels N.; Hillewaert, K.
2016-01-01
at low and high Reynolds numbers and compares the results to state-of-the-art models used in industry, namely the panel method (XFOIL with boundary layer modeling) and Reynolds Averaged Navier-Stokes (RANS). At low Reynolds number (Re = 6 × 104), involving laminar boundary layer separation and transition...... in the detached shear layer, the Eppler 387 airfoil is studied at two angles of attack. The LES results agree slightly better with the experimental chordwise pressure distribution than both XFOIL and RANS results. At high Reynolds number (Re = 1.64 × 106), the NACA4412 airfoil is studied close to stall condition...
The effects of nozzle geometry on waterjet breakup at high Reynolds numbers
Energy Technology Data Exchange (ETDEWEB)
Vahedi Tafreshi, H.; Pourdeyhimi, B. [Nonwovens Cooperative Research Center, North Carolina State University, NC 27695-8301, Raleigh (United States)
2003-10-01
Waterjet breakup is traditionally considered to follow the Ohnesorge classification. In this classification, high Reynolds number waterjets are considered to atomize quickly after discharge. By generating a constricted waterjet where the water flow stays detached all the way through the nozzle, we have observed the first wind-induced breakup mode at high Reynolds numbers. Such a peculiar behavior, however, was not observed in non-constricted waterjets. Our results indicate that, constricted jets do not follow the Ohnesorge classification, in contrast to the non-constricted waterjets. We discuss the impact of nozzle geometry on the characteristics of waterjets and support our discussion by numerical simulations. (orig.)
Reynolds Number, Compressibility, and Leading-Edge Bluntness Effects on Delta-Wing Aerodynamics
Luckring, James M.
2004-01-01
An overview of Reynolds number, compressibility, and leading edge bluntness effects is presented for a 65 degree delta wing. The results of this study address both attached and vortex-flow aerodynamics and are based upon a unique data set obtained in the NASA-Langley National Transonic Facility (NTF) for i) Reynolds numbers ranging from conventional wind-tunnel to flight values, ii) Mach numbers ranging from subsonic to transonic speeds, and iii) leading-edge bluntness values that span practical slender wing applications. The data were obtained so as to isolate the subject effects and they present many challenges for Computational Fluid Dynamics (CFD) studies.
A Multicoefficient Slip-Corrected Reynolds Equation for Micro-Thin Film Gas Lubrication
Directory of Open Access Journals (Sweden)
Ng Eddie Yin-Kwee
2005-01-01
Full Text Available This work investigates and analyzes the performance of conventional slip models among various regimes of Knudsen number and developes a new multicoefficient slip-velocity model, by using Taguchi quality control techniques and numerical analysis. A modified Reynolds equation is also derived based on the new slip-flow model. The multicoefficient slip model and its slip-corrected Reynolds equation are suitable to a wide Knudsen range from slip to transition regime. In comparison with other conventional slip models, it is found that the current results have a better agreement with the solution obtained from the linearized Boltzmann equation and direct simulation of Monte Carlo method (DSMC.
Mary Reynolds: a post-traumatic reinterpretation of a classic case of multiple personality disorder.
Goodwin, J
1987-01-01
In 1811 Mary Reynolds, a somber Pennsylvania spinster, awoke from a prolonged sleep as a new personality. Family memoirs describing her 18 years of shifts between two personalities shaped nineteenth century thinking about multiple personality disorder. As in other early case histories, no mention was made of childhood trauma, a factor found in 97% of contemporary cases. This discussion reviews genealogical and historical documents which suggest that Mary Reynolds did experience early trauma as a victim of religious persecution, which finally forced her family to leave Birmingham, England, when Mary was eight. Review of her illness indicates it may have functioned to eradicate memories of traumatic early experiences.
Challenges in simulating coastal effects on an offshore wind farm
DEFF Research Database (Denmark)
van der Laan, Paul; Peña, Alfredo; Volker, Patrick
2017-01-01
The effect of a coastline on an offshore wind farm is investigated with a Reynolds-averaged Navier-Stokes (RANS) model. The trends of the RANS model compare relatively well with results from a mesoscale model and measurements of wind turbine power. In addition, challenges of modeling a large domain...
Energy Technology Data Exchange (ETDEWEB)
Kim, Hyun Chang; Lee, Hoyoung; Khetan, Jawahar; Won, You-Yeon [Purdue
2016-02-01
Air–water interfacial monolayers of poly((d,l-lactic acid-ran-glycolic acid)-block-ethylene glycol) (PLGA–PEG) exhibit an exponential increase in surface pressure under high monolayer compression. In order to understand the molecular origin of this behavior, a combined experimental and theoretical investigation (including surface pressure–area isotherm, X-ray reflectivity (XR) and interfacial rheological measurements, and a self-consistent field (SCF) theoretical analysis) was performed on air–water monolayers formed by a PLGA–PEG diblock copolymer and also by a nonglassy analogue of this diblock copolymer, poly((d,l-lactic acid-ran-glycolic acid-ran-caprolactone)-block-ethylene glycol) (PLGACL–PEG). The combined results of this study show that the two mechanisms, i.e., the glass transition of the collapsed PLGA film and the lateral repulsion of the PEG brush chains that occur simultaneously under lateral compression of the monolayer, are both responsible for the observed PLGA–PEG isotherm behavior. Upon cessation of compression, the high surface pressure of the PLGA–PEG monolayer typically relaxes over time with a stretched exponential decay, suggesting that in this diblock copolymer situation, the hydrophobic domain formed by the PLGA blocks undergoes glass transition in the high lateral compression state, analogously to the PLGA homopolymer monolayer. In the high PEG grafting density regime, the contribution of the PEG brush chains to the high monolayer surface pressure is significantly lower than what is predicted by the SCF model because of the many-body attraction among PEG segments (referred to in the literature as the “n-cluster” effects). The end-grafted PEG chains were found to be protein resistant even under the influence of the “n-cluster” effects.
Kim, Hyun Chang; Lee, Hoyoung; Khetan, Jawahar; Won, You-Yeon
2015-12-29
Air-water interfacial monolayers of poly((D,L-lactic acid-ran-glycolic acid)-block-ethylene glycol) (PLGA-PEG) exhibit an exponential increase in surface pressure under high monolayer compression. In order to understand the molecular origin of this behavior, a combined experimental and theoretical investigation (including surface pressure-area isotherm, X-ray reflectivity (XR) and interfacial rheological measurements, and a self-consistent field (SCF) theoretical analysis) was performed on air-water monolayers formed by a PLGA-PEG diblock copolymer and also by a nonglassy analogue of this diblock copolymer, poly((D,L-lactic acid-ran-glycolic acid-ran-caprolactone)-block-ethylene glycol) (PLGACL-PEG). The combined results of this study show that the two mechanisms, i.e., the glass transition of the collapsed PLGA film and the lateral repulsion of the PEG brush chains that occur simultaneously under lateral compression of the monolayer, are both responsible for the observed PLGA-PEG isotherm behavior. Upon cessation of compression, the high surface pressure of the PLGA-PEG monolayer typically relaxes over time with a stretched exponential decay, suggesting that in this diblock copolymer situation, the hydrophobic domain formed by the PLGA blocks undergoes glass transition in the high lateral compression state, analogously to the PLGA homopolymer monolayer. In the high PEG grafting density regime, the contribution of the PEG brush chains to the high monolayer surface pressure is significantly lower than what is predicted by the SCF model because of the many-body attraction among PEG segments (referred to in the literature as the "n-cluster" effects). The end-grafted PEG chains were found to be protein resistant even under the influence of the "n-cluster" effects.
Chatziioannou, Aristotelis A; Moulos, Panagiotis
2011-01-01
StRAnGER is a web application for the automated statistical analysis of annotated gene profiling experiments, exploiting controlled biological vocabularies, like the Gene Ontology or the KEGG pathways terms. Starting from annotated lists of differentially expressed genes and gene enrichment scores, regarding the terms of each vocabulary, StRAnGER repartitions and reorders the initial distribution of terms to define a new distribution of elements. Each element pools terms holding the same enrichment score. The new distribution thus derived, is reordered in a decreasing order to the right, according to the observation score of the elements, while elements with the same score, are sorted again in a decreasing order of their enrichment scores. By applying bootstrapping techniques, a corrected measure of the statistical significance of these elements is derived, which enables the selection of terms mapped to these elements, unambiguously associated with respective significant gene sets. The selected terms are immunized against the bias infiltrating statistical enrichment analyses, producing technically very high statistical scores, due to the finite nature of the data population. Besides their high statistical score, another selection criterion for the terms is the number of their members, something that incurs a biological prioritization in line with a Systems Biology context. The output derived, represents a detailed ranked list of significant terms, which constitute a starting point for further functional analysis.
Directory of Open Access Journals (Sweden)
Aristotle A Chatziioannou
2011-01-01
Full Text Available StRAnGER is a web application for the automated statistical analysis of annotated gene profiling experiments, exploiting controlled biological vocabularies, like the Gene Ontology or the KEGG pathways terms. Starting from annotated lists of differentially expressed genes and gene enrichment scores, regarding the terms of each vocabulary, StRAnGER repartitions and reorders the initial distribution of terms to define a new distribution of elements. Each element pools terms holding the same enrichment score. The new distribution thus derived, is reordered in a decreasing order to the right, according to the observation score of the elements, while elements with the same score, are sorted again in a decreasing order of their enrichment scores. By applying bootstrapping techniques, a corrected measure of the statistical significance of these elements is derived, which enables the selection of terms mapped to these elements, unambiguously associated with respective significant gene sets. The selected terms are immunized against the bias infiltrating statistical enrichment analyses, producing technically very high statistical scores, due to the finite nature of the data population. Besides their high statistical score, another selection criterion for the terms is the number of their members, something that incurs a biological prioritization in line with a Systems Biology context. The output derived, represents a detailed ranked list of significant terms, which constitute a starting point for further functional analysis.
Gendron, Tania F; Cosio, Danielle M; Petrucelli, Leonard
2013-09-01
A hexanucleotide (GGGGCC) repeat expansion within a non-coding region of the C9ORF72 gene is the most common mutation associated with both frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). Elucidating how these expanded repeats (GGGGCCexp) cause 'c9FTD/ALS' has since become an important goal of the FTD/ALS field. GGGGCCexp transcripts aggregate into discrete nuclear structures, termed RNA foci. This phenomenon, observed in various repeat expansion disorders, is associated with RNA-binding protein sequestration. Of note, recent findings show that GGGGCCexp transcripts also succumb to an alternative fate: repeat-associated non-ATG translation (RAN translation). This unconventional mode of translation, which occurs in the absence of an initiating codon, results in the production of polyGA, polyGP and polyGR peptides. Antibodies generated against these peptides detect high molecular weight, insoluble material in brain homogenates, as well as neuronal inclusions throughout the central nervous system of c9FTD/ALS cases. Given that both foci formation and RAN translation in c9FTD/ALS require the synthesis of GGGGCCexp RNA, therapeutic strategies that target these transcripts and result in their neutralization or degradation could effectively block these two potential pathogenic mechanisms and provide a much needed treatment for c9FTD/ALS.
The average size of ordered binary subgraphs
van Leeuwen, J.; Hartel, Pieter H.
To analyse the demands made on the garbage collector in a graph reduction system, the change in size of an average graph is studied when an arbitrary edge is removed. In ordered binary trees the average number of deleted nodes as a result of cutting a single edge is equal to the average size of a
High-Lift Low Reynolds Number Aerofoils With Specified Pressure Drop for Ducted Wind Turbine
Tang, J.; van Bussel, G.J.W.
2017-01-01
A new high-lift aerofoil modification for the duct has been developed and will be experimentally tested in a small wind tunnel. Aerofoils for such wind tunnel ducts typically operate in the low Reynolds number range from 2 × 105 to 6 × 105. The effect of a duct and of rotor on power and pressure
Gravitational sedimentation of cloud of solid spherical particles at small Reynolds numbers
Directory of Open Access Journals (Sweden)
Arkhipov Vladimir
2015-01-01
Full Text Available The experimental results of study of gravitational sedimentation of highly-concentrated systems of solid spherical particles at small Reynolds numbers Re<1 are presented. Empirical equation for drag coefficient of the particle assembly has been obtained. The influence of initial particle concentration in the cloud on its dynamics and velocity has been analysed.
Numerical study on the flow characteristics of micro air vehicle wings at low Reynolds numbers
Xiao, Tianhang; Li, Zhengzhou; Deng, S.; Ang, Haisong; Zhou, Xinchun
2016-01-01
The aerodynamic characteristics around a micro air vehicle wing with an inverse-Zimmerman configuration are numerically investigated by an in-house programmed solver particularly dedicated for aircrafts operating in low Reynolds number regime. The complex three-dimensional aerodynamic performance
Wissocq, Gauthier; Gourdain, Nicolas; Malaspinas, Orestis; Eyssartier, Alexandre
2017-02-01
This paper reports the investigations done to adapt the Characteristic Boundary Conditions (CBC) to the Lattice-Boltzmann formalism for high Reynolds number applications. Three CBC formalisms are implemented and tested in an open source LBM code: the baseline local one-dimension inviscid (BL-LODI) approach, its extension including the effects of the transverse terms (CBC-2D) and a local streamline approach in which the problem is reformulated in the incident wave framework (LS-LODI). Then all implementations of the CBC methods are tested for a variety of test cases, ranging from canonical problems (such as 2D plane and spherical waves and 2D vortices) to a 2D NACA profile at high Reynolds number (Re =105), representative of aeronautic applications. The LS-LODI approach provides the best results for pure acoustics waves (plane and spherical waves). However, it is not well suited to the outflow of a convected vortex for which the CBC-2D associated with a relaxation on density and transverse waves provides the best results. As regards numerical stability, a regularized adaptation is necessary to simulate high Reynolds number flows. The so-called regularized FD (Finite Difference) adaptation, a modified regularized approach where the off-equilibrium part of the stress tensor is computed thanks to a finite difference scheme, is the only tested adaptation that can handle the high Reynolds computation.
Time dependent heat transfer rates in high Reynolds number hypersonic flowfields
Flanagan, Michael J.
1992-01-01
Time dependent heat transfer rates have been calculated from time dependent temperature measurements in the vicinity of shock-wave boundary-layer interactions due to conical compression ramps on an axisymmetric body. The basic model is a cylindrical body with a 10 degree conical nose. Four conical ramps, 20, 25, 30, and 35 degrees serve as shock wave generators. Flowfield surveys have been made in the vicinity of the conical ramp vertex, the separation point, and the reattachment point. A significant effort was made to characterize the natural frequencies and relative powers of the resulting fluctuations in heat transfer rates. This research effort, sponsored jointly by NASA and the Air Force, was conducted in the Air Force Flight Dynamics Directorate High Reynolds Facility. The nominal freestream Mach number was 6, and the freestream Reynolds numbers ranged from 2.2 million/ft to 30.0 million/ft. Experimental results quantify temperature response and the resulting heat transfer rates as a function of ramp angle and Reynolds number. The temperature response within the flowfield appears to be steady-state for all compression ramp angles and all Reynolds numbers, and hence, the heat transfer rates appear to be steady-state.
Multigrid solution of the convection-diffusion equation with high-Reynolds number
Energy Technology Data Exchange (ETDEWEB)
Zhang, Jun [George Washington Univ., Washington, DC (United States)
1996-12-31
A fourth-order compact finite difference scheme is employed with the multigrid technique to solve the variable coefficient convection-diffusion equation with high-Reynolds number. Scaled inter-grid transfer operators and potential on vectorization and parallelization are discussed. The high-order multigrid method is unconditionally stable and produces solution of 4th-order accuracy. Numerical experiments are included.
Coupled ADCPs can yield complete Reynolds stress tensor profiles in geophysical surface flows
Vermeulen, B.; Hoitink, A.J.F.; Sassi, M.G.
2011-01-01
We introduce a new technique to measure profiles of each term in the Reynolds stress tensor using coupled acoustic Doppler current profilers (ADCPs). The technique is based on the variance method which is extended to the case with eight acoustic beams. Methods to analyze turbulence from a single
High Reynolds Number Micro-Bubble and Polymer Drag Reduction Experiments
2008-01-01
test model. Appendix A: Smooth-Flat-Plate Turbulent Boundary Layer Measurements at High Reynolds Number Ghanem F. Oweis’, Eric S. Winkel’, James M...a 15’-full-angle triangular wedge of 0.6- m length that was terminated at 25 mm thickness with 400 bevel angle. This asymmetric trailing edge design
Flow Control Methods and Their Applicability in Low-Reynolds-Number Centrifugal Compressors—A Review
Directory of Open Access Journals (Sweden)
Jonna Tiainen
2017-12-01
Full Text Available The decrease in the performance of centrifugal compressors operating at low Reynolds numbers (e.g., unmanned aerial vehicles at high altitudes or small turbomachines can reach 10% due to increased friction. The purposes of this review are to represent the state-of-the-art of the active and passive flow control methods used to improve performance and/or widen the operating range in numerous engineering applications, and to investigate their applicability in low-Reynolds-number centrifugal compressors. The applicable method should increase performance by reducing drag, increasing blade loading, or reducing tip leakage. Based on the aerodynamic and structural demands, passive methods like riblets, squealers, winglets and grooves could be beneficial; however, the drawbacks of these approaches are that their performance depends on the operating conditions and the effect might be negative at higher Reynolds numbers. The flow control method, which would reduce the boundary layer thickness and reduce wake, could have a beneficial impact on the performance of a low-Reynolds-number compressor in the entire operating range, but none of the methods represented in this review fully fulfil this objective.
Factorial Validity of the Reynolds Intellectual Assessment Scales for Referred Students
Beaujean, A. Alexander; McGlaughlin, Sean M.; Margulies, Allison S.
2009-01-01
The Reynolds Intellectual Assessment Scales (RIAS) is a recently developed, individually administered psychometric instrument designed to measure general cognitive ability, as well as verbal (crystallized) intelligence, nonverbal (fluid) intelligence, and memory. Test reviewers have recommended the use of the RIAS despite the fact that, although…
A numerical study on effect of corner radius and Reynolds number ...
Indian Academy of Sciences (India)
The effects of the parameters such as Reynolds number and corner radius on the drag and laminar boundary layer have been studied for the first time. The results are shown in the form of drag coefficient, boundary layer and pressure coefficient on the cylinder surface. It is found that the boundary layer thickness and the ...
A NUMERICAL INVESTIGATION OF BUBBLES RISING AT INTERMEDIATE REYNOLDS AND LARGE WEBER NUMBERS
HOFFMANN, AC; VANDENBOGAARD, HA
The steady state rise of bubbles at intermediate Reynolds numbers and large Weber numbers has been investigated using finite element simulations. The velocity and stress fields are discussed. Near-constant normal stress profiles over a region around the bubble apex could be generated by optimizing
A comparison of time integration methods in an unsteady low-Reynolds-number flow
Majander, Petri; Siikonen, Timo
2002-06-01
This paper describes three different time integration methods for unsteady incompressible Navier-Stokes equations. Explicit Euler and fractional-step Adams-Bashford methods are compared with an implicit three-level method based on a steady-state SIMPLE method. The implicit solver employs a dual time stepping and an iteration within the time step. The spatial discretization is based on a co-located finite-volume technique. The influence of the convergence limits and the time-step size on the accuracy of the predictions are studied. The efficiency of the different solvers is compared in a vortex-shedding flow over a cylinder in the Reynolds number range of 100-1600. A high-Reynolds-number flow over a biconvex airfoil profile is also computed. The computations are performed in two dimensions. At the low-Reynolds-number range the explicit methods appear to be faster by a factor from 5 to 10. In the high-Reynolds-number case, the explicit Adams-Bashford method and the implicit method appear to be approximately equally fast while yielding similar results. Copyright
Reynolds stress scaling in pipe flow turbulence—first results from CICLoPE
Örlü, R.; Fiorini, T.; Segalini, A.; Bellani, G.; Talamelli, A.; Alfredsson, P. H.
2017-03-01
This paper reports the first turbulence measurements performed in the Long Pipe Facility at the Center for International Cooperation in Long Pipe Experiments (CICLoPE). In particular, the Reynolds stress components obtained from a number of straight and boundary-layer-type single-wire and X-wire probes up to a friction Reynolds number of 3.8×104 are reported. In agreement with turbulent boundary-layer experiments as well as with results from the Superpipe, the present measurements show a clear logarithmic region in the streamwise variance profile, with a Townsend-Perry constant of A2≈1.26. The wall-normal variance profile exhibits a Reynolds-number-independent plateau, while the spanwise component was found to obey a logarithmic scaling over a much wider wall-normal distance than the other two components, with a slope that is nearly half of that of the Townsend-Perry constant, i.e. A2,w≈A2/2. The present results therefore provide strong support for the scaling of the Reynolds stress tensor based on the attached-eddy hypothesis. Intriguingly, the wall-normal and spanwise components exhibit higher amplitudes than in previous studies, and therefore call for follow-up studies in CICLoPE, as well as other large-scale facilities.
Aerodynamic Analysis of Open Trailing Edge Airfoils at Low Reynolds Number
Sant Palma, Rodolfo; Ayuso Moreno, Luis Manuel; Meseguer Ruiz, José
2011-01-01
A study has been made on the influence of the open trailing edge in airfoils used in different devices relating their aerodynamic performances. Wind tunnel tests have been made at different Reynolds numbers and angles of attack in order to show this effect. Besides, a quantitative study of the aerodynamic properties has been made based on the different trailing edge thickness
TR-PIV measurement of the wake behind a grooved cylinder at low Reynolds number
Liu, Ying Zheng; Shi, Liu Liu; Yu, Jun
2011-04-01
A comparative study of the wakes behind cylinders with grooved and smooth surfaces was performed with a view to understand the wake characteristics associated with the adult Saguaro cacti. A low-speed recirculation water channel was established for the experiment; the Reynolds number, based on the free-stream velocity and cylinder diameter (D), was kept at ReD=1500. State-of-the-art time-resolved particle image velocimetry (TR-PIV) was employed to measure a total of 20 480 realizations of the wake field at a frame rate of 250 Hz, enabling a comprehensive view of the time- and phase-averaged wake pattern. In comparison to the wake behind the smooth cylinder, the length of the recirculation zone behind the grooved cylinder was extended by nearly 18.2%, yet the longitudinal velocity fluctuation intensity was considerably weakened. A global view of the peaked spectrum of the longitudinal velocity component revealed that the intermediate region for the grooved cylinder, which approximately corresponds to the transition region where the shear layer vortices interact, merge and shed before the formation of the Karman-like vortex street, was much wider than that for the smooth one. The unsteady events near St=0.3-0.4 were detected in the intermediate region behind the grooved cylinder, but no such events were found in the smooth cylinder system. Although the formation of the Karman-like vortex street was delayed by about 0.6D downstream for the grooved cylinder, no prominent difference in the vortex street region was found in the far wake for both cylinders. The Proper Orthogonal Decomposition (POD) method was used extensively to decompose the vector and swirling strength fields, which gave a close-up view of the vortices in the near wake. The first two POD modes of the swirling strength clarified the spatio-temporal characteristics of the shear layer vortices behind the grooved cylinder. The small-scale vortices superimposed on the shear layers behind the grooved cylinder
Large Eddy Simulation of an SD7003 Airfoil: Effects of Reynolds number and Subgrid-scale modeling
DEFF Research Database (Denmark)
Sarlak Chivaee, Hamid
2017-01-01
This paper presents results of a series of numerical simulations in order to study aerodynamic characteristics of the low Reynolds number Selig-Donovan airfoil, SD7003. Large Eddy Simulation (LES) technique is used for all computations at chord-based Reynolds numbers 10,000, 24,000 and 60...
Kelley, Joshua B.; Datta, Sutirtha; Snow, Chelsi J.; Chatterjee, Mandovi; Ni, Li; Spencer, Adam; Yang, Chun-Song; Cubeñas-Potts, Caelin; Matunis, Michael J.; Paschal, Bryce M.
2011-01-01
The mutant form of lamin A responsible for the premature aging disease Hutchinson-Gilford progeria syndrome (termed progerin) acts as a dominant negative protein that changes the structure of the nuclear lamina. How the perturbation of the nuclear lamina in progeria is transduced into cellular changes is undefined. Using patient fibroblasts and a variety of cell-based assays, we determined that progerin expression in Hutchinson-Gilford progeria syndrome inhibits the nucleocytoplasmic transport of several factors with key roles in nuclear function. We found that progerin reduces the nuclear/cytoplasmic concentration of the Ran GTPase and inhibits the nuclear localization of Ubc9, the sole E2 for SUMOylation, and of TPR, the nucleoporin that forms the basket on the nuclear side of the nuclear pore complex. Forcing the nuclear localization of Ubc9 in progerin-expressing cells rescues the Ran gradient and TPR import, indicating that these pathways are linked. Reducing nuclear SUMOylation decreases the nuclear mobility of the Ran nucleotide exchange factor RCC1 in vivo, and the addition of SUMO E1 and E2 promotes the dissociation of RCC1 and Ran from chromatin in vitro. Our data suggest that the cellular effects of progerin are transduced, at least in part, through reduced function of the Ran GTPase and SUMOylation pathways. PMID:21670151
Letizia, Stefano; Puccioni, Matteo; Zhan, Lu; Viola, Francesco; Camarri, Simone; Iungo, Giacomo Valerio
2017-11-01
Numerical simulations of wakes produced by utility-scale wind turbines still present challenges related to the variability of the atmospheric conditions and, in the most of the cases, the lack of information about the geometry and aerodynamic performance of the wind turbine blades. In order to overcome the mentioned difficulties, we propose a RANS solver for which turbine aerodynamic forcing and turbulence closure are calibrated through LiDAR and SCADA data acquired for an onshore wind farm. The wind farm under examination is located in North Texas over a relatively flat terrain. The experimental data are leveraged to maximize accuracy of the RANS predictions in terms of wake velocity field and power capture for different atmospheric stability conditions and settings of the wind turbines. The optimization of the RANS parameters is performed through an adjoint-RANS formulation and a gradient-based procedure. The optimally-tuned aerodynamic forcing and turbulence closure are then analyzed in order to investigate effects of the atmospheric stability on the evolution of wind turbine wakes and power performance. The proposed RANS solver has low computational costs comparable to those of wake engineering models, which make it a compelling tool for wind farm control and optimization. Acknowledgments: NSF I/UCRC WindSTAR IIP 1362033 and TACC.
Reynolds stress scaling in pipe flow turbulence-first results from CICLoPE.
Örlü, R; Fiorini, T; Segalini, A; Bellani, G; Talamelli, A; Alfredsson, P H
2017-03-13
This paper reports the first turbulence measurements performed in the Long Pipe Facility at the Center for International Cooperation in Long Pipe Experiments (CICLoPE). In particular, the Reynolds stress components obtained from a number of straight and boundary-layer-type single-wire and X-wire probes up to a friction Reynolds number of 3.8×10(4) are reported. In agreement with turbulent boundary-layer experiments as well as with results from the Superpipe, the present measurements show a clear logarithmic region in the streamwise variance profile, with a Townsend-Perry constant of A2≈1.26. The wall-normal variance profile exhibits a Reynolds-number-independent plateau, while the spanwise component was found to obey a logarithmic scaling over a much wider wall-normal distance than the other two components, with a slope that is nearly half of that of the Townsend-Perry constant, i.e. A2,w≈A2/2. The present results therefore provide strong support for the scaling of the Reynolds stress tensor based on the attached-eddy hypothesis. Intriguingly, the wall-normal and spanwise components exhibit higher amplitudes than in previous studies, and therefore call for follow-up studies in CICLoPE, as well as other large-scale facilities.This article is part of the themed issue 'Toward the development of high-fidelity models of wall turbulence at large Reynolds number'. © 2017 The Author(s).
A Mobility Management Using Follow-Me Cloud-Cloudlet in Fog-Computing-Based RANs for Smart Cities.
Chen, Yuh-Shyan; Tsai, Yi-Ting
2018-02-06
Mobility management for supporting the location tracking and location-based service (LBS) is an important issue of smart city by providing the means for the smooth transportation of people and goods. The mobility is useful to contribute the innovation in both public and private transportation infrastructures for smart cities. With the assistance of edge/fog computing, this paper presents a fully new mobility management using the proposed follow-me cloud-cloudlet (FMCL) approach in fog-computing-based radio access networks (Fog-RANs) for smart cities. The proposed follow-me cloud-cloudlet approach is an integration strategy of follow-me cloud (FMC) and follow-me edge (FME) (or called cloudlet). A user equipment (UE) receives the data, transmitted from original cloud, into the original edge cloud before the handover operation. After the handover operation, an UE searches for a new cloud, called as a migrated cloud, and a new edge cloud, called as a migrated edge cloud near to UE, where the remaining data is migrated from the original cloud to the migrated cloud and all the remaining data are received in the new edge cloud. Existing FMC results do not have the property of the VM migration between cloudlets for the purpose of reducing the transmission latency, and existing FME results do not keep the property of the service migration between data centers for reducing the transmission latency. Our proposed FMCL approach can simultaneously keep the VM migration between cloudlets and service migration between data centers to significantly reduce the transmission latency. The new proposed mobility management using FMCL approach aims to reduce the total transmission time if some data packets are pre-scheduled and pre-stored into the cache of cloudlet if UE is switching from the previous Fog-RAN to the serving Fog-RAN. To illustrate the performance achievement, the mathematical analysis and simulation results are examined in terms of the total transmission time, the
A Mobility Management Using Follow-Me Cloud-Cloudlet in Fog-Computing-Based RANs for Smart Cities
Directory of Open Access Journals (Sweden)
Yuh-Shyan Chen
2018-02-01
Full Text Available Mobility management for supporting the location tracking and location-based service (LBS is an important issue of smart city by providing the means for the smooth transportation of people and goods. The mobility is useful to contribute the innovation in both public and private transportation infrastructures for smart cities. With the assistance of edge/fog computing, this paper presents a fully new mobility management using the proposed follow-me cloud-cloudlet (FMCL approach in fog-computing-based radio access networks (Fog-RANs for smart cities. The proposed follow-me cloud-cloudlet approach is an integration strategy of follow-me cloud (FMC and follow-me edge (FME (or called cloudlet. A user equipment (UE receives the data, transmitted from original cloud, into the original edge cloud before the handover operation. After the handover operation, an UE searches for a new cloud, called as a migrated cloud, and a new edge cloud, called as a migrated edge cloud near to UE, where the remaining data is migrated from the original cloud to the migrated cloud and all the remaining data are received in the new edge cloud. Existing FMC results do not have the property of the VM migration between cloudlets for the purpose of reducing the transmission latency, and existing FME results do not keep the property of the service migration between data centers for reducing the transmission latency. Our proposed FMCL approach can simultaneously keep the VM migration between cloudlets and service migration between data centers to significantly reduce the transmission latency. The new proposed mobility management using FMCL approach aims to reduce the total transmission time if some data packets are pre-scheduled and pre-stored into the cache of cloudlet if UE is switching from the previous Fog-RAN to the serving Fog-RAN. To illustrate the performance achievement, the mathematical analysis and simulation results are examined in terms of the total transmission time
Numerical simulations on a twin-plate wake
DEFF Research Database (Denmark)
Fernández-Gámiz, U.; Velte, Clara Marika; Egusquiza, E.
2013-01-01
In this work, a detailed numerical analysis of two dimensional mean velocity profiles downstream of two parallel flat plates was carried out at a Reynolds number of 3.2x104 (based on the plate length and free stream velocity) using Reynolds Averaged Navier-Stokes (RANS) and have been compared wit...
2D study of wind forces around multiple cooling towers using ...
African Journals Online (AJOL)
A comprehensive numerical study for the determination of wind pressure coefficients on multiple cooling towers by simulating turbulence using Reynolds Averaged Navier-Stokes Equations (RANS) models of Computational Fluid Dynamics techniques (CFD) such as, Standard k −ε , RNG k −ε , Realizable k −ε and Reynolds ...
Directory of Open Access Journals (Sweden)
Yoke-Peng Lee
Full Text Available Under the fluctuating circumstances provided by the innate dynamics of microtubules and opposing tensions resulted from microtubule-associated motors, it is vital to ensure stable kinetochore-microtubule attachments for accurate segregation. However, a comprehensive understanding of how this regulation is mechanistically achieved remains elusive. Using our newly designed live cell FRET time-lapse imaging, we found that post-metaphase RanGTP is crucial in the maintenance of stable kinetochore-microtubule attachments by regulating Aurora B kinase via the NES-bearing Mst1. More importantly, our study demonstrates that by ensuring stable alignment of metaphase chromosomes prior to segregation, RanGTP is indispensible in governing the genomic integrity and the fidelity of cell cycle progression. Our findings suggest an additional role of RanGTP beyond its known function in mitotic spindle assembly during the prometaphase-metaphase transition.
NOAA Average Annual Salinity (3-Zone)
California Department of Resources — The 3-Zone Average Annual Salinity Digital Geography is a digital spatial framework developed using geographic information system (GIS) technology. These salinity...
DEFF Research Database (Denmark)
Taudal Poulsen, René
2016-01-01
Review of: Lenka Krátká: A History of the Czechoslovak Ocean Shipping Company, 1948–1989: How a Small, Landlocked Country Ran Maritime Business During the Cold War. Stuttgart: Ibidem Verlag, 2015. x + 271 pp., tables, notes, bibliography. ISBN: 978-3-8382-0666-0, £23.90 (pbk).......Review of: Lenka Krátká: A History of the Czechoslovak Ocean Shipping Company, 1948–1989: How a Small, Landlocked Country Ran Maritime Business During the Cold War. Stuttgart: Ibidem Verlag, 2015. x + 271 pp., tables, notes, bibliography. ISBN: 978-3-8382-0666-0, £23.90 (pbk)....
A singularity theorem based on spatial averages
Indian Academy of Sciences (India)
Open non-rotating Universes, expanding everywhere with a non-vanishing spatial average of the matter variables, show severe geodesic incompletness in the past. Another way of stating the result is that, under the same conditions, any singularity-free model must have a vanishing spatial average of the energy density ...
Evaluation of edge detectors using average risk
Spreeuwers, Lieuwe Jan; van der Heijden, Ferdinand
1992-01-01
A new method for evaluation of edge detectors, based on the average risk of a decision, is discussed. The average risk is a performance measure well-known in Bayesian decision theory. Since edge detection can be regarded as a compound decision making process, the performance of an edge detector is
Determinants of College Grade Point Averages
Bailey, Paul Dean
2012-01-01
Chapter 2: The Role of Class Difficulty in College Grade Point Averages. Grade Point Averages (GPAs) are widely used as a measure of college students' ability. Low GPAs can remove a students from eligibility for scholarships, and even continued enrollment at a university. However, GPAs are determined not only by student ability but also by the…
Averaging Einstein's equations : The linearized case
Stoeger, William R.; Helmi, Amina; Torres, Diego F.
We introduce a simple and straightforward averaging procedure, which is a generalization of one which is commonly used in electrodynamics, and show that it possesses all the characteristics we require for linearized averaging in general relativity and cosmology for weak-field and perturbed FLRW
Energy Technology Data Exchange (ETDEWEB)
Massol, A.
2004-02-15
The application of statistically averaged two-fluid models for the simulation of complex indus- trial two-phase flows requires the development of adequate models for the drag force exerted on the inclusions and the interfacial heat exchange. This task becomes problematic at high volume fractions of the dispersed phase. The quality of the simulation strongly depends upon the inter- facial exchange terms, starting with the steady drag force. For example, an accurate modelling of the drag force is therefore a crucial point to simulate the expansion of dense fluidized beds. Most models used to study the exchange terms between particles and fluids are based on the interaction between an isolated particle and a surrounding gas. Those models are clearly not adequate in cases where the volume fraction of particles increases and particle-particle interactions become important. Studying such cases is a complex task because of the multiple possible configurations. While the interaction between an isolated sphere and a gas depends only on the particle size and the slip velocity between gas and particles, the interaction between a cloud of particles and a gas depends on many more parameters: size and velocity distribution of particles, relative position of particles. Even if the particles keep relative fixed positions, there is an infinite number of combinations to construct such an array. The objective of the present work is to perform steady and unsteady simulations of the flow in regular arrays of fixed particles in order to analyze the influence of the size and distributions of spheres on drag force and heat transfer (the array of spheres can be either monodispersed, either bi-dispersed). Several authors have studied the drag exerted on the spheres, but only for low Reynolds numbers and/or solid volume fractions close to the packed limit. Moreover some discrepancies are observed between the different studies. On top of that, all existing studies are limited to steady flows
Energy Technology Data Exchange (ETDEWEB)
Kawamura, T.; Nakao, T.; Takahashi, M.; Hayashi, M.; Goto, N. [Hitachi, Ltd., Tokyo (Japan)
1999-07-25
Vortex-induced vibrations were measured for a circular cylinder subjected to a water cross flow at supercritical Reynolds numbers for a wide range of reduced velocities. Turbulence intensities were changed from 1% to 13% in order to investigate the effect of the Strouhal number on the region of synchronization by symmetrical and Karman vortex shedding. The reduced damping of the test cylinder was about 0.1 in water. The surface roughness of the cylinder was a mirror-polished surface. Strouhal number decreased from about 0.48 to 0.29 with increasing turbulence intensity. Synchronized vibrations were observed even at supercritical Reynolds numbers where fluctuating fluid force was small. Reduced velocities at which drag and lift direction lock-in by Karman vortex shedding were initiated decreased with increasing Strouhal number. When Strouhal number was about 0.29, the self-excited vibration in drag direction by symmetrical vortex shedding began at which the frequency ratio of Karman vortex shedding frequency to the natural frequency of cylinder was 0.32. (author)
Multipartite analysis of average-subsystem entropies
Alonso-Serrano, Ana; Visser, Matt
2017-11-01
So-called average subsystem entropies are defined by first taking partial traces over some pure state to define density matrices, then calculating the subsystem entropies, and finally averaging over the pure states to define the average subsystem entropies. These quantities are standard tools in quantum information theory, most typically applied in bipartite systems. We shall first present some extensions to the usual bipartite analysis (including a calculation of the average tangle and a bound on the average concurrence), follow this with some useful results for tripartite systems, and finally extend the discussion to arbitrary multipartite systems. A particularly nice feature of tripartite and multipartite analyses is that this framework allows one to introduce an "environment" to which small subsystems can couple.
Reynolds number influence on the formation of vortical structures on a pitching flat plate.
Widmann, Alexander; Tropea, Cameron
2017-02-06
The impact of chord-based Reynolds number on the formation of leading-edge vortices (LEVs) on unsteady pitching flat plates is investigated. The influence of secondary flow structures on the shear layer feeding the LEV and the subsequent topological change at the leading edge as the result of viscous processes are demonstrated. Time-resolved velocity fields are measured using particle image velocimetry simultaneously in two fields of view to correlate local and global flow phenomena in order to identify unsteady boundary-layer separation and the subsequent flow structures. Finally, the Reynolds number is identified as a parameter that is responsible for the transition in mechanisms leading to LEV detachment from an aerofoil, as it determines the viscous response of the boundary layer in the vortex-wall interaction.
Theory of viscous transonic flow over airfoils at high Reynolds number
Melnik, R. E.; Chow, R.; Mead, H. R.
1977-01-01
This paper considers viscous flows with unseparated turbulent boundary layers over two-dimensional airfoils at transonic speeds. Conventional theoretical methods are based on boundary layer formulations which do not account for the effect of the curved wake and static pressure variations across the boundary layer in the trailing edge region. In this investigation an extended viscous theory is developed that accounts for both effects. The theory is based on a rational analysis of the strong turbulent interaction at airfoil trailing edges. The method of matched asymptotic expansions is employed to develop formal series solutions of the full Reynolds equations in the limit of Reynolds numbers tending to infinity. Procedures are developed for combining the local trailing edge solution with numerical methods for solving the full potential flow and boundary layer equations. Theoretical results indicate that conventional boundary layer methods account for only about 50% of the viscous effect on lift, the remaining contribution arising from wake curvature and normal pressure gradient effects.
Study of Nonlinear MHD Tribological Squeeze Film at Generalized Magnetic Reynolds Numbers Using DTM.
Directory of Open Access Journals (Sweden)
Mohammad Mehdi Rashidi
Full Text Available In the current article, a combination of the differential transform method (DTM and Padé approximation method are implemented to solve a system of nonlinear differential equations modelling the flow of a Newtonian magnetic lubricant squeeze film with magnetic induction effects incorporated. Solutions for the transformed radial and tangential momentum as well as solutions for the radial and tangential induced magnetic field conservation equations are determined. The DTM-Padé combined method is observed to demonstrate excellent convergence, stability and versatility in simulating the magnetic squeeze film problem. The effects of involved parameters, i.e. squeeze Reynolds number (N1, dimensionless axial magnetic force strength parameter (N2, dimensionless tangential magnetic force strength parameter (N3, and magnetic Reynolds number (Rem are illustrated graphically and discussed in detail. Applications of the study include automotive magneto-rheological shock absorbers, novel aircraft landing gear systems and biological prosthetics.
Study of Nonlinear MHD Tribological Squeeze Film at Generalized Magnetic Reynolds Numbers Using DTM.
Rashidi, Mohammad Mehdi; Freidoonimehr, Navid; Momoniat, Ebrahim; Rostami, Behnam
2015-01-01
In the current article, a combination of the differential transform method (DTM) and Padé approximation method are implemented to solve a system of nonlinear differential equations modelling the flow of a Newtonian magnetic lubricant squeeze film with magnetic induction effects incorporated. Solutions for the transformed radial and tangential momentum as well as solutions for the radial and tangential induced magnetic field conservation equations are determined. The DTM-Padé combined method is observed to demonstrate excellent convergence, stability and versatility in simulating the magnetic squeeze film problem. The effects of involved parameters, i.e. squeeze Reynolds number (N1), dimensionless axial magnetic force strength parameter (N2), dimensionless tangential magnetic force strength parameter (N3), and magnetic Reynolds number (Rem) are illustrated graphically and discussed in detail. Applications of the study include automotive magneto-rheological shock absorbers, novel aircraft landing gear systems and biological prosthetics.
2009-01-01
natural transition production term Re = Reynolds number based on axial chord 1...turbine. As aircraft altitude increases, the operational Reynolds number decreases due to the change in density. The low Reynolds number causes the...cooling and a flat plate with pressure distribution similar to an axial compressor undergoing passing wakes by Walters and Leylek 10,11 . The intent of
Cosmic inhomogeneities and averaged cosmological dynamics.
Paranjape, Aseem; Singh, T P
2008-10-31
If general relativity (GR) describes the expansion of the Universe, the observed cosmic acceleration implies the existence of a "dark energy." However, while the Universe is on average homogeneous on large scales, it is inhomogeneous on smaller scales. While GR governs the dynamics of the inhomogeneous Universe, the averaged homogeneous Universe obeys modified Einstein equations. Can such modifications alone explain the acceleration? For a simple generic model with realistic initial conditions, we show the answer to be "no." Averaging effects negligibly influence the cosmological dynamics.
Lift Production on Flapping and Rotary Wings at Low Reynolds Numbers
2016-02-26
lift- generating mechanisms and relate flow structures to the unsteady forces generated by the wing, synchronized flow visualization, force measurements... generated at the leading edge to drain from the LEV into the tip vortex. At higher Reynolds numbers (Re = 8,000), periodically shedding vortices have been...controlled model motion. The motor assembly, shown in Figure 3(a), is mounted on the towing carriage and contains two brushless linear motors, and a
Computational Investigation of Unsteady Low-Reynolds Number Aerodynamics for Micro Air Vehicles
2007-03-01
amplitude and frequency, and Strouhal number are studied. For a symmetric plunging airfoil NACA0012 at zero geometric angle of attack and chord Reynolds...transition method.1 321 Particle tracking and Streakline integration Lai and Platzer visualized the wake structure of airfoil NACA0012 exerting plunging...interpolation. Results and Discussion 6 For demonstration purpose, we use the NACA0012 airfoil throughout this work. The readers should be aware that in real
Energy Technology Data Exchange (ETDEWEB)
Zhou, Ye [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Thornber, Ben [The Univ. of Sydney, Sydney, NSW (Australia)
2016-04-12
Here, the implicit large-eddy simulation (ILES) has been utilized as an effective approach for calculating many complex flows at high Reynolds number flows. Richtmyer–Meshkov instability (RMI) induced flow can be viewed as a homogeneous decaying turbulence (HDT) after the passage of the shock. In this article, a critical evaluation of three methods for estimating the effective Reynolds number and the effective kinematic viscosity is undertaken utilizing high-resolution ILES data. Effective Reynolds numbers based on the vorticity and dissipation rate, or the integral and inner-viscous length scales, are found to be the most self-consistent when compared to the expected phenomenology and wind tunnel experiments.
Analysis of Zero Reynolds Shear Stress Appearing in Dilute Surfactant Drag-Reducing Flow
Directory of Open Access Journals (Sweden)
Weiguo Gu
2011-01-01
Full Text Available Dilute surfactant solution of 25 ppm in the two-dimensional channel is investigated experimentally compared with water flow. Particle image velocimetry (PIV system is used to take 2D velocity frames in the streamwise and wall-normal plane. Based on the frames of instantaneous vectors and statistical results, the phenomenon of zero Reynolds shear stress appearing in the drag-reducing flow is discussed. It is found that 25 ppm CTAC solution exhibits the highest drag reduction at Re = 25000 and loses drag reduction completely at Re = 40000. When drag reduction lies in the highest, Reynolds shear stress disappears and reaches zero although the RMS of the velocity fluctuations is not zero. By the categorization in four quadrants, the fluctuations of 25 ppm CTAC solution are distributed in all four quadrants equally at Re = 25000, which indicates that turnaround transportation happens in drag-reducing flow besides Reynolds shear stress transportation. Moreover, the contour distribution of streamwise velocity and the fluctuations suggests that turbulence transportation is depressed in drag-reducing flow. The viscoelasticity is possible to decrease the turbulence transportation and cause the turnaround transportation.
Chua, John Christian; Lopez, Neil Stephen; Augusto, Gerardo
2017-11-01
Low Reynolds number aerodynamics has become a promising topic of interest in various commercial utilizations such as wind turbines. Airfoils employed for this type of application usually experience performance degradation due to separation bubble formation. This study intends to investigate the behavior and effect of such phenomena and analyze the interrelationship among the contributive factors affecting its existence using JMP, a statistical analysis tool, with numerical data generated from Xfoil, a collective program applicable for low-speed airfoils. Numerical results were validated against published experimental data and exhibited favorable agreement more specifically within the upper limits of the given Reynolds number range. Surface pressure and skin friction drag coefficient plots show that the bubble length tends to decrease as angle of attack, Reynolds number and turbulence intensity are increased. The abridgement of the bubble extent due to enhancement of flow instabilities is associated with increase lift-to-drag ratio which is more pronounced in the attached flow regions. The statistical technique yielded predictive models for multiple outcome variables and it was learned that the main effects had more significant influence on the aerodynamic properties of airfoils and chordwise extent of separation bubble.
Scour around a single Marine Hydrokinetic turbine of varying tip speed ratio and Reynolds number
Volpe, M. A.; Beninati, M. L.; Krane, M.; Fontaine, A.
2012-12-01
Experiments are presented to explore how the sediment scour around a single Marine Hydrokinetic (MHK) turbine varies with both tip speed ratio (TSR) and flow Reynolds number. The sediment size (d50 = 790 microns) and the turbine blade diameter (0.1016 m) were held constant for all tests. Three tip speed ratios (TSR = 5, 6, and 7) and three Reynolds numbers, based on turbine blade diameter, (ReD = 31500, 35800, and 40000) were used. The MHK device is a two-bladed horizontal axis turbine and the rotating shaft is loaded using a metal brush motor. The experiments were performed in the small-scale testing platform in the hydraulic flume facility (9.8 m long, 1.2 m wide and 0.4 m deep) at Bucknell University. For each test case, bed form topology was measured after a three-hour time interval using a traversing two-dimensional bed profiler. During the experiment, scour depth measurements at the front face of the cylindrical support structure were taken to estimate a scour rate. Measurements of the bed form were taken in 1/8 diameter increments across the width of the test section. Results show that the scour hole dimensions (depth, width, length) and deposition behind the turbine increase with both TSR and Reynolds number.
Control of wing-tip vortex using winglets at low Reynolds number
Cho, Seunghyun; Choi, Haecheon
2014-11-01
Winglets are considered as one of the effective devices for reducing induced drag, and thus many studies have been conducted, but mainly at high Reynolds numbers (Re ~106 ~107) for commercial airplanes. However, small-size unmanned air vehicles (UAV), operating at low Reynolds numbers (Re aerodynamic performance of an UAV by varying the cant angle. The WASP UAV model is used and the Reynolds numbers considered are 110,000 ~ 140,000 based on the free stream velocity and mean chord length of the WASP wing. The lift and drag forces on UAV are measured, and PIV measurements are conducted at several cross-flow planes for a few different angles of attack (α) . At high angles of attack (7° ~13°) , the winglets with the cant angle of 70° increase the aerodynamic performance, whereas at low angles of attack (2° ~6°) , the wing-tip extension (cant angle of 0°) shows better performances. The velocity fields measured from PIV indicate that, with the winglet, the wing-tip vortex moves away from the wing surface at α =12° , and the downwash motion in the wake behind the trailing edge is decreased, reducing the magnitude of the induced drag. A concept of changing the cant angle during flight is also suggested at this talk. Supported by 2011-0028032.
Numerical Upscaling of Transport Through Obstructed Regions Over a Broad Range of Reynolds Numbers
Sund, N. L.; Bolster, D.; Mattis, S. A.
2014-12-01
While historically flow and transport in porous media has focused on low Reynolds number and Peclet number regimes there are a variety of examples relevant to environmental fluid dynamics where higher Reynolds number flows are important. A common example might include flow and transport through wetlands where plants act as the solid phase of an effective porous medium. In particular, heterogeneity in the flow field due to presence of the solid phases gives rise to complex transport and mixing behaviors that cannot be upscaled at pre-asymptotic times using conventional approaches. We numerically simulate pore-scale flow and transport through obstructed domains over a range of Reynolds numbers from 15 to 280 and then upscale transport. We upscale using a correlated continuous time random walk (correlated CTRW) model, originally introduced in [1]. We then assess the correlated CTRW's ability to predict observables for both asymptotic and pre-asymptotic time scales and compare our results to those of a classical CTRW to determine when velocity correlations must be accounted for. REFERENCES[1] T.L. Borgne, M. Dentz, J. Carrera: Lagrangian statistical model for transport in highly heterogeneous velocity fields, Physical Review Letters 101 (2008) 090601.
Reynolds number effects on the single-mode Richtmyer-Meshkov instability
Walchli, B.; Thornber, B.
2017-01-01
The Reynolds number effects on the nonlinear growth rates of the Richtmyer-Meshkov instability are investigated using two-dimensional numerical simulations. A decrease in Reynolds number gives an increased time to reach nonlinear saturation, with Reynolds number effects only significant in the range ReSohn's model [S.-I. Sohn, Phys. Rev. E 80, 055302 (2009), 10.1103/PhysRevE.80.055302]. Predicted amplitudes show reasonable agreement with the existing theory of Carles and Popinet [P. Carles and S. Popinet, Phys. Fluids Lett. 13, 1833 (2001), 10.1063/1.1377863; Eur. J. Mech. B 21, 511 (2002), 10.1016/S0997-7546(02)01199-8] and Mikaelian [K. O. Mikaelian, Phys. Rev. E 47, 375 (1993), 10.1103/PhysRevE.47.375; K. O. Mikaelian, Phys. Rev. E 87, 031003 (2013), 10.1103/PhysRevE.87.031003], with the former being the closest match to the current computations.
Turbulence Intermittency Characteristics in the Reynolds Number Range 100 <= R_λ <= 1,000
Gylfason, Armann; Ayyalasomayajula, Sathyanarayanana; Warhaft, Zellman
2002-11-01
Work by Tabeling and collaborators^1 show a transitional behavior in the flatness factor of the velocity derivative, K_partial u/ partial x, as a function of Taylor Reynolds number, R_λ ≡ u λ / ν. Their results show a peak in K_partial u/partial x at R_λ ˜ 700 followed by a decrease (to R_λ ˜ 1000) before returning to a gentle increase. Here we investigate K_partial u / partial x in decaying, active grid, turbulence. Our preliminary results show that K_partial u / partial x increases until R_λ ˜ 700 and then remains approximately flat to R_λ ˜ 1,200 (the extent of our measurements). Thus there is some similarity with the Tabeling et al. work, although our data does not exhibit the pronounced peak and trough that they observe. Reasons for the differences are investigated, including differences in flow geometry and the possibility that the Taylor scale Reynolds number does not map linearly from one flow to another. Other recent proposals^2 of Reynolds numbers based purely on the small scales are investigated. Transverse velocity statistics and velocity difference measurements are also presented. The work is supported by the National Science Foundation. [1] P. Tabeling et al. PRE, 53, 1613 (1996); Tabeling and Willaime, PRE, 65, 066301--1 (2002). [2] R.H. Hill. J. Fluid Mech., 463, 403 (2002).
Averaging of Legendrian submanifolds of contact manifolds
Zambon, Marco
2004-01-01
We give a procedure to ``average'' canonically $C^1$-close Legendrian submanifolds of contact manifolds. As a corollary we obtain that, whenever a compact group action leaves a Legendrian submanifold almost invariant, there is an invariant Legendrian submanifold nearby.
Average Annual Precipitation (PRISM model) 1961 - 1990
U.S. Geological Survey, Department of the Interior — This map layer shows polygons of average annual precipitation in the contiguous United States, for the climatological period 1961-1990. Parameter-elevation...
Monthly snow/ice averages (ISCCP)
National Aeronautics and Space Administration — September Arctic sea ice is now declining at a rate of 11.5 percent per decade, relative to the 1979 to 2000 average. Data from NASA show that the land ice sheets in...
Quetelet, the average man and medical knowledge
National Research Council Canada - National Science Library
Caponi, Sandra
2013-01-01
Using two books by Adolphe Quetelet, I analyze his theory of the 'average man', which associates biological and social normality with the frequency with which certain characteristics appear in a population...
Site Averaged AMS Data: 1988 (Betts)
National Aeronautics and Space Administration — Site averaged product of the Portable Automatic Meteorological Station (AMS) data acquired during the 1987-1989 FIFE experiment. Data are in 30-minute time intervals...
MN Temperature Average (1961-1990) - Line
Minnesota Department of Natural Resources — This data set depicts 30-year averages (1961-1990) of monthly and annual temperatures for Minnesota. Isolines and regions were created using kriging and...
Average Vegetation Growth 1993 - Direct Download
U.S. Geological Survey, Department of the Interior — This map layer is a grid map of 1993 average vegetation growth for Alaska and the conterminous United States. The nominal spatial resolution is 1 kilometer and the...
Average Vegetation Growth 2001 - Direct Download
U.S. Geological Survey, Department of the Interior — This map layer is a grid map of 2001 average vegetation growth for Alaska and the conterminous United States. The nominal spatial resolution is 1 kilometer and the...
Average Vegetation Growth 1999 - Direct Download
U.S. Geological Survey, Department of the Interior — This map layer is a grid map of 1999 average vegetation growth for Alaska and the conterminous United States. The nominal spatial resolution is 1 kilometer and the...
Average Vegetation Growth 2005 - Direct Download
U.S. Geological Survey, Department of the Interior — This map layer is a grid map of 2005 average vegetation growth for Alaska and the conterminous United States. The nominal spatial resolution is 1 kilometer and the...
Average Vegetation Growth 1996 - Direct Download
U.S. Geological Survey, Department of the Interior — This map layer is a grid map of 1996 average vegetation growth for Alaska and the conterminous United States. The nominal spatial resolution is 1 kilometer and the...
Average Vegetation Growth 1992 - Direct Download
U.S. Geological Survey, Department of the Interior — This map layer is a grid map of 1992 average vegetation growth for Alaska and the conterminous United States. The nominal spatial resolution is 1 kilometer and the...
Average Vegetation Growth 2000 - Direct Download
U.S. Geological Survey, Department of the Interior — This map layer is a grid map of 2000 average vegetation growth for Alaska and the conterminous United States. The nominal spatial resolution is 1 kilometer and the...
Average Vegetation Growth 2003 - Direct Download
U.S. Geological Survey, Department of the Interior — This map layer is a grid map of 2003 average vegetation growth for Alaska and the conterminous United States. The nominal spatial resolution is 1 kilometer and the...
Average Vegetation Growth 2004 - Direct Download
U.S. Geological Survey, Department of the Interior — This map layer is a grid map of 2004 average vegetation growth for Alaska and the conterminous United States. The nominal spatial resolution is 1 kilometer and the...
A practical guide to averaging functions
Beliakov, Gleb; Calvo Sánchez, Tomasa
2016-01-01
This book offers an easy-to-use and practice-oriented reference guide to mathematical averages. It presents different ways of aggregating input values given on a numerical scale, and of choosing and/or constructing aggregating functions for specific applications. Building on a previous monograph by Beliakov et al. published by Springer in 2007, it outlines new aggregation methods developed in the interim, with a special focus on the topic of averaging aggregation functions. It examines recent advances in the field, such as aggregation on lattices, penalty-based aggregation and weakly monotone averaging, and extends many of the already existing methods, such as: ordered weighted averaging (OWA), fuzzy integrals and mixture functions. A substantial mathematical background is not called for, as all the relevant mathematical notions are explained here and reported on together with a wealth of graphical illustrations of distinct families of aggregation functions. The authors mainly focus on practical applications ...
Appeals Council Requests - Average Processing Time
Social Security Administration — This dataset provides annual data from 1989 through 2015 for the average processing time (elapsed time in days) for dispositions by the Appeals Council (AC) (both...
Sea Surface Temperature Average_SST_Master
National Oceanic and Atmospheric Administration, Department of Commerce — Sea surface temperature collected via satellite imagery from http://www.esrl.noaa.gov/psd/data/gridded/data.noaa.ersst.html and averaged for each region using ArcGIS...
An approximate analytical approach to resampling averages
DEFF Research Database (Denmark)
Malzahn, Dorthe; Opper, M.
2004-01-01
Using a novel reformulation, we develop a framework to compute approximate resampling data averages analytically. The method avoids multiple retraining of statistical models on the samples. Our approach uses a combination of the replica "trick" of statistical physics and the TAP approach...... for approximate Bayesian inference. We demonstrate our approach on regression with Gaussian processes. A comparison with averages obtained by Monte-Carlo sampling shows that our method achieves good accuracy....
Microprocessor-based boxcar signal averager
Bano, S. S.; Reddy, P. N.; Reddy, B. P. N.; Eswara Reddy, N. C.
1987-10-01
A boxcar signal averager using Intel 8085AH, an 8-bit microprocessor developed for processing free-induction decay (FID) signals from a pulsed nuclear-magnetic-resonance (NMR) spectrometer, is described. The boxcar signal averager works either in single-point mode or in scan mode. In addition to the software developed, the constructional features, circuit details, and the operation of the boxcar are discussed in detail.
Average Bandwidth Allocation Model of WFQ
Directory of Open Access Journals (Sweden)
Tomáš Balogh
2012-01-01
Full Text Available We present a new iterative method for the calculation of average bandwidth assignment to traffic flows using a WFQ scheduler in IP based NGN networks. The bandwidth assignment calculation is based on the link speed, assigned weights, arrival rate, and average packet length or input rate of the traffic flows. We prove the model outcome with examples and simulation results using NS2 simulator.
Wang, Hongjie; Wang, Ruizhi; Xu, Shaohua; Lakshmana, Madepalli K
2014-01-01
There is now compelling evidence that the neurodegenerative process in Alzheimer's disease (AD) begins in synapses. Loss of synaptic proteins and functional synapses in the amyloid precursor protein (APP) transgenic mouse models of AD is well established. However, what is the earliest age at which such loss of synapses occurs, and whether known markers of AD progression accelerate functional deficits is completely unknown. We previously showed that RanBP9 overexpression leads to robustly increased amyloid β peptide (Aβ) generation leading to enhanced amyloid plaque burden in a mouse model of AD. In this study we compared synaptic protein levels among four genotypes of mice, i.e., RanBP9 single transgenic (Ran), APΔE9 double transgenic (Dbl), APΔE9/RanBP9 triple transgenic (Tpl) and wild-type (WT) controls. We found significant reductions in the levels of synaptic proteins in both cortex and hippocampus of 5- and 6-months-old but not 3- or 4-months-old mice. Specifically, at 5-months of age, rab3A was reduced in the triple transgenic mice only in the cortex by 25% (pproteins in the mouse brain.
Directory of Open Access Journals (Sweden)
Evi Blaikie
2011-01-01
Full Text Available Ozsvath, Zsuzsanna. When the Danube Ran Red. Syracuse University Press, 2010,171 pp., Illus.Mandel, Eva Marika. Le Livre de Mana. Paris, Glyphe 2009, 231 pp., Illus.Roth, Marika. All the Pretty Shoes; A Memoir of Survival and the Feminine SpiritWyatt McKenzy 2010, 254 pp., Illus.Reviewed by Evi Blaikie, Freelance Writer.
Directory of Open Access Journals (Sweden)
Christian eBarbato
2014-02-01
Full Text Available Neurodegeneration associated with amyloid β (Aβ peptide accumulation, synaptic loss, and memory impairment are pathophysiological features of Alzheimer's disease (AD. Numerous microRNAs regulate amyloid precursor protein (APP expression and metabolism. We previously reported that miR-101 is a negative regulator of APP expression in cultured hippocampal neurons. In this study, a search for predicted APP metabolism-associated miR-101 targets led to the identification of a conserved miR-101 binding site within the 3’ untranslated region (UTR of the mRNA encoding Ran-binding protein 9 (RanBP9. RanBP9 increases APP processing by β-amyloid converting enzyme 1 (BACE1, secretion of soluble APPβ (sAPPβ, and generation of Aβ. MiR-101 significantly reduced reporter gene expression when co-transfected with a RanBP9 3'-UTR reporter construct, while site-directed mutagenesis of the predicted miR-101 target site eliminated the reporter response. To investigate the effect of stable inhibition of miR-101 both in vitro and in vivo, a microRNA sponge was developed to bind miR-101 and derepress its targets. Four tandem bulged miR-101 responsive elements (REs, located downstream of the enhanced green fluorescence protein (EGFP open reading frame and driven by the synapsin promoter, were placed in a lentiviral vector to create the pLSyn-miR-101 sponge. Delivery of the sponge to primary hippocampal neurons significantly increased both APP and RanBP9 expression, as well as sAPPβ levels in the conditioned medium. Importantly, silencing of endogenous RanBP9 reduced sAPPβ levels in miR-101 sponge-containing hippocampal cultures, indicating that miR-101 inhibition may increase amyloidogenic processing of APP by RanBP9. Lastly, the impact of miR-101 on its targets was demonstrated in vivo by intrahippocampal injection of the pLSyn-miR-101 sponge into C57BL6 mice. This study thus provides the basis for studying the consequences of long-term miR-101 inhibition on
The concept of the average eye
Directory of Open Access Journals (Sweden)
R.D. van Gool
2005-01-01
Full Text Available For most quantitative studies one needs to calculate an average. In the case of refraction an average is readily computed as the arithmetic average of dioptric power matrices. Refraction, however, is only one aspect of the first-order optical character of an eye. The question is: How does one determine an average that rep-resents the average optical character of a set of eyes completely to first order? The exponen-tial-mean-log transference has been proposed recently but it is not without its difficulties. There are four matrices, naturally related to the transference and called the characteristics or characteristic matrices, whose mathematical features suggest that they may provide alterna-tive solutions to the problem of the average eye. Accordingly the purpose of this paper is to propose averages based on these characteristics, to examine their nature and to calculate and compare them in the case of a particular sample of 30 eyes. The eyes may be stigmatic or astig-matic and component elements may be centred or decentred. None turns out to be a perfect average. One of the four averages (that based on one of the two mixed characteristics is proba-bly of little or no use in the context of eyes. The other three, particularly the point-characteristic average, seem to be potentially useful.
Directory of Open Access Journals (Sweden)
Yu Han
2017-01-01
Full Text Available We report the development of a new analytical model similar to the Reynolds-averaged Navier-Stokes equations to determine the distribution of streamwise velocity by considering the bursting phenomenon. It is found that, in two-dimensional (2D flows, the underlying mechanism of the wake law in 2D uniform flow is actually a result of up/down events. A special experiment was conducted to examine the newly derived analytical model, and good agreement is achieved between the experimental data in the inner region and the model’s prediction. The obtained experimental data were also used to examine the DML-Law (dip-modified-log-law, MLW-Law (modified-log-wake law, and CML-Law (Cole’s wake law, and the agreement is not very satisfactory in the outer region.
Steffen, C. J., Jr.
1993-01-01
Turbulent backward-facing step flow was examined using four low turbulent Reynolds number k-epsilon models and one standard high Reynolds number technique. A tunnel configuration of 1:9 (step height: exit tunnel height) was used. The models tested include: the original Jones and Launder; Chien; Launder and Sharma; and the recent Shih and Lumley formulation. The experimental reference of Driver and Seegmiller was used to make detailed comparisons between reattachment length, velocity, pressure, turbulent kinetic energy, Reynolds shear stress, and skin friction predictions. The results indicated that the use of a wall function for the standard k-epsilon technique did not reduce the calculation accuracy for this separated flow when compared to the low turbulent Reynolds number techniques.
Energy Technology Data Exchange (ETDEWEB)
Tanahashi, T.; Nakai, T. [Keio University, Tokyo (Japan). Faculty of Engineering
1995-12-15
Generally speaking, finite element methods in the computational fluid dynamics are universal, but not economical. In the present paper in order to overcome this defect ill FEM, we propose a new method using the discrete del operator which is a coordinate-free differential operator in the discrete space. This operator in the discrete space is defined as an element average of the gradient of the shape function and it has three characteristics such as orthogonality, identity and symmetricity. Furthermore the discrete del operator is useful in non-memorizing and in easy coding. As the analytical expression of the discrete del operator is a vector in the two or three dimensions, the natural description of programming becomes objective and compact, which is more understandable for non-specialists of CFD. Here we apply this method to thermal fluid flows at high Reynolds numbers. 10 refs., 5 figs., 1 tab.
Amano, R. S.; Chai, J. C.
1988-01-01
A study is made for the development and computations of the separating and reattaching shear flows. The highlight of the study is an attempt to predict the third-moments of turbulent velocity which is responsible for the diffusion transport of the Reynolds stresses. The present computations show that the third-moments obtained by employing the low-Reynolds number model of transport equations improve the prediction of the third-moments.
Asynchronous Gossip for Averaging and Spectral Ranking
Borkar, Vivek S.; Makhijani, Rahul; Sundaresan, Rajesh
2014-08-01
We consider two variants of the classical gossip algorithm. The first variant is a version of asynchronous stochastic approximation. We highlight a fundamental difficulty associated with the classical asynchronous gossip scheme, viz., that it may not converge to a desired average, and suggest an alternative scheme based on reinforcement learning that has guaranteed convergence to the desired average. We then discuss a potential application to a wireless network setting with simultaneous link activation constraints. The second variant is a gossip algorithm for distributed computation of the Perron-Frobenius eigenvector of a nonnegative matrix. While the first variant draws upon a reinforcement learning algorithm for an average cost controlled Markov decision problem, the second variant draws upon a reinforcement learning algorithm for risk-sensitive control. We then discuss potential applications of the second variant to ranking schemes, reputation networks, and principal component analysis.
Backus and Wyllie Averages for Seismic Attenuation
Qadrouh, Ayman N.; Carcione, José M.; Ba, Jing; Gei, Davide; Salim, Ahmed M.
2017-09-01
Backus and Wyllie equations are used to obtain average seismic velocities at zero and infinite frequencies, respectively. Here, these equations are generalized to obtain averages of the seismic quality factor (inversely proportional to attenuation). The results indicate that the Wyllie velocity is higher than the corresponding Backus quantity, as expected, since the ray velocity is a high-frequency limit. On the other hand, the Wyllie quality factor is higher than the Backus one, following the velocity trend, i.e., the higher the velocity (the stiffer the medium), the higher the attenuation. Since the quality factor can be related to properties such as porosity, permeability, and fluid viscosity, these averages can be useful for evaluating reservoir properties.
Stochastic Averaging and Stochastic Extremum Seeking
Liu, Shu-Jun
2012-01-01
Stochastic Averaging and Stochastic Extremum Seeking develops methods of mathematical analysis inspired by the interest in reverse engineering and analysis of bacterial convergence by chemotaxis and to apply similar stochastic optimization techniques in other environments. The first half of the text presents significant advances in stochastic averaging theory, necessitated by the fact that existing theorems are restricted to systems with linear growth, globally exponentially stable average models, vanishing stochastic perturbations, and prevent analysis over infinite time horizon. The second half of the text introduces stochastic extremum seeking algorithms for model-free optimization of systems in real time using stochastic perturbations for estimation of their gradients. Both gradient- and Newton-based algorithms are presented, offering the user the choice between the simplicity of implementation (gradient) and the ability to achieve a known, arbitrary convergence rate (Newton). The design of algorithms...
Matrix averages relating to Ginibre ensembles
Energy Technology Data Exchange (ETDEWEB)
Forrester, Peter J [Department of Mathematics and Statistics, University of Melbourne, Victoria 3010 (Australia); Rains, Eric M [Department of Mathematics, California Institute of Technology, Pasadena, CA 91125 (United States)], E-mail: p.forrester@ms.unimelb.edu.au
2009-09-25
The theory of zonal polynomials is used to compute the average of a Schur polynomial of argument AX, where A is a fixed matrix and X is from the real Ginibre ensemble. This generalizes a recent result of Sommers and Khoruzhenko (2009 J. Phys. A: Math. Theor. 42 222002), and furthermore allows analogous results to be obtained for the complex and real quaternion Ginibre ensembles. As applications, the positive integer moments of the general variance Ginibre ensembles are computed in terms of generalized hypergeometric functions; these are written in terms of averages over matrices of the same size as the moment to give duality formulas, and the averages of the power sums of the eigenvalues are expressed as finite sums of zonal polynomials.
Changing mortality and average cohort life expectancy
DEFF Research Database (Denmark)
Schoen, Robert; Canudas-Romo, Vladimir
2005-01-01
Period life expectancy varies with changes in mortality, and should not be confused with the life expectancy of those alive during that period. Given past and likely future mortality changes, a recent debate has arisen on the usefulness of the period life expectancy as the leading measure......, the average cohort life expectancy (ACLE), to provide a precise measure of the average length of life of cohorts alive at a given time. To compare the performance of ACLE with CAL and with period and cohort life expectancy, we first use population models with changing mortality. Then the four aggregate...... of survivorship. An alternative aggregate measure of period mortality which has been seen as less sensitive to period changes, the cross-sectional average length of life (CAL) has been proposed as an alternative, but has received only limited empirical or analytical examination. Here, we introduce a new measure...
Books average previous decade of economic misery.
Bentley, R Alexander; Acerbi, Alberto; Ormerod, Paul; Lampos, Vasileios
2014-01-01
For the 20(th) century since the Depression, we find a strong correlation between a 'literary misery index' derived from English language books and a moving average of the previous decade of the annual U.S. economic misery index, which is the sum of inflation and unemployment rates. We find a peak in the goodness of fit at 11 years for the moving average. The fit between the two misery indices holds when using different techniques to measure the literary misery index, and this fit is significantly better than other possible correlations with different emotion indices. To check the robustness of the results, we also analysed books written in German language and obtained very similar correlations with the German economic misery index. The results suggest that millions of books published every year average the authors' shared economic experiences over the past decade.
When Is the Local Average Treatment Close to the Average? Evidence from Fertility and Labor Supply
Ebenstein, Avraham
2009-01-01
The local average treatment effect (LATE) may differ from the average treatment effect (ATE) when those influenced by the instrument are not representative of the overall population. Heterogeneity in treatment effects may imply that parameter estimates from 2SLS are uninformative regarding the average treatment effect, motivating a search for…
Ma, Wenyong; Liu, Qingkuan; Du, Xiaoqing; Liu, Xiaobing
2017-08-01
The mechanism of large-amplitude aeroelastic vibrations of cylindrical bodies in the critical Reynolds number range are still unclear. This study concerns the aerodynamic forces acting on elliptical cylinders and the induced galloping instability resulting from skew flows (i.e., the direction of the flow is angled 0°-45° with respect to the central axis of the cylinder) for Reynolds numbers in the range of 37-235 k. The effects of the critical Reynolds number and the skew angle on the aerodynamic forces and the galloping instability are investigated with pressure wind tunnel tests. In all of the cases investigated in the present study, a sharp decrease in the lift coefficient with increasing angle of attack and a reduction in the drag coefficient at the critical Reynolds number could be responsible for the galloping instability. Variations in the torque coefficient leads to a torsional aerodynamic instability at the critical Reynolds number. Furthermore, the skew flow cause a critical flow state at lower Reynolds numbers. One possible reason for this behavior is that the longer effective cross section allows the flow to reattach.
Directory of Open Access Journals (Sweden)
Haiqing Si
2015-03-01
Full Text Available Lattice Boltzmann method combined with large eddy simulation is developed in the article to simulate fluid flow at high Reynolds numbers. A subgrid model is used as a large eddy simulation model in the numerical simulation for high Reynolds flow. The idea of subgrid model is based on an assumption to include the physical effects that the unresolved motion has on the resolved fluid motion. It takes a simple form of eddy viscosity models for the Reynolds stress. Lift and drag evaluation in the lattice Boltzmann equation takes momentum-exchange method for curved body surface. First of all, the present numerical method is validated at low Reynolds numbers. Second, the developed lattice Boltzmann method/large eddy simulation method is performed to solve flow problems at high Reynolds numbers. Some detailed quantitative comparisons are implemented to show the effectiveness of the present method. It is demonstrated that lattice Boltzmann method combined with large eddy simulation model can efficiently simulate high Reynolds numbers’ flows.
Energy Technology Data Exchange (ETDEWEB)
Choi, Min Suk; Baek, Je Hyun [Pohang University of Science and Technology, Pohang (Korea, Republic of); Chung, Hee Taeg [Gyeongsang National University, Jinju (Korea, Republic of); Oh, Seong Hwan; Ko, Han Young [Agency for Defense Development, Daejeon (Korea, Republic of)
2008-02-15
A three-dimensional computation was conducted to understand effects of the low Reynolds number on the performance in a low-speed axial compressor at the design condition. The low Reynolds number can originates from the change of the air density because it decreases along the altitude in the troposphere. The performance of the axial compressor such as the static pressure rise was diminished by the separation on the suction surface with full span and the boundary layer on the hub, which were caused by the low Reynolds number. The total pressure loss at the low Reynolds number was found to be greater than that at the reference Reynolds number at the region from the hub to 85% span. Total pressure loss was scrutinized through three major loss categories in a subsonic axial compressor such as the profile loss, the tip leakage loss and the endwall loss using Denton's loss model, and the effects of the low Reynolds number on the performance were analyzed in detail.
Average-case analysis of numerical problems
2000-01-01
The average-case analysis of numerical problems is the counterpart of the more traditional worst-case approach. The analysis of average error and cost leads to new insight on numerical problems as well as to new algorithms. The book provides a survey of results that were mainly obtained during the last 10 years and also contains new results. The problems under consideration include approximation/optimal recovery and numerical integration of univariate and multivariate functions as well as zero-finding and global optimization. Background material, e.g. on reproducing kernel Hilbert spaces and random fields, is provided.
An improved moving average technical trading rule
Papailias, Fotis; Thomakos, Dimitrios D.
2015-06-01
This paper proposes a modified version of the widely used price and moving average cross-over trading strategies. The suggested approach (presented in its 'long only' version) is a combination of cross-over 'buy' signals and a dynamic threshold value which acts as a dynamic trailing stop. The trading behaviour and performance from this modified strategy are different from the standard approach with results showing that, on average, the proposed modification increases the cumulative return and the Sharpe ratio of the investor while exhibiting smaller maximum drawdown and smaller drawdown duration than the standard strategy.
Model averaging and muddled multimodel inferences.
Cade, Brian S
2015-09-01
Three flawed practices associated with model averaging coefficients for predictor variables in regression models commonly occur when making multimodel inferences in analyses of ecological data. Model-averaged regression coefficients based on Akaike information criterion (AIC) weights have been recommended for addressing model uncertainty but they are not valid, interpretable estimates of partial effects for individual predictors when there is multicollinearity among the predictor variables. Multicollinearity implies that the scaling of units in the denominators of the regression coefficients may change across models such that neither the parameters nor their estimates have common scales, therefore averaging them makes no sense. The associated sums of AIC model weights recommended to assess relative importance of individual predictors are really a measure of relative importance of models, with little information about contributions by individual predictors compared to other measures of relative importance based on effects size or variance reduction. Sometimes the model-averaged regression coefficients for predictor variables are incorrectly used to make model-averaged predictions of the response variable when the models are not linear in the parameters. I demonstrate the issues with the first two practices using the college grade point average example extensively analyzed by Burnham and Anderson. I show how partial standard deviations of the predictor variables can be used to detect changing scales of their estimates with multicollinearity. Standardizing estimates based on partial standard deviations for their variables can be used to make the scaling of the estimates commensurate across models, a necessary but not sufficient condition for model averaging of the estimates to be sensible. A unimodal distribution of estimates and valid interpretation of individual parameters are additional requisite conditions. The standardized estimates or equivalently the t
The modulated average structure of mullite.
Birkenstock, Johannes; Petříček, Václav; Pedersen, Bjoern; Schneider, Hartmut; Fischer, Reinhard X
2015-06-01
Homogeneous and inclusion-free single crystals of 2:1 mullite (Al(4.8)Si(1.2)O(9.6)) grown by the Czochralski technique were examined by X-ray and neutron diffraction methods. The observed diffuse scattering together with the pattern of satellite reflections confirm previously published data and are thus inherent features of the mullite structure. The ideal composition was closely met as confirmed by microprobe analysis (Al(4.82 (3))Si(1.18 (1))O(9.59 (5))) and by average structure refinements. 8 (5) to 20 (13)% of the available Si was found in the T* position of the tetrahedra triclusters. The strong tendencey for disorder in mullite may be understood from considerations of hypothetical superstructures which would have to be n-fivefold with respect to the three-dimensional average unit cell of 2:1 mullite and n-fourfold in case of 3:2 mullite. In any of these the possible arrangements of the vacancies and of the tetrahedral units would inevitably be unfavorable. Three directions of incommensurate modulations were determined: q1 = [0.3137 (2) 0 ½], q2 = [0 0.4021 (5) 0.1834 (2)] and q3 = [0 0.4009 (5) -0.1834 (2)]. The one-dimensional incommensurately modulated crystal structure associated with q1 was refined for the first time using the superspace approach. The modulation is dominated by harmonic occupational modulations of the atoms in the di- and the triclusters of the tetrahedral units in mullite. The modulation amplitudes are small and the harmonic character implies that the modulated structure still represents an average structure in the overall disordered arrangement of the vacancies and of the tetrahedral structural units. In other words, when projecting the local assemblies at the scale of a few tens of average mullite cells into cells determined by either one of the modulation vectors q1, q2 or q3 a weak average modulation results with slightly varying average occupation factors for the tetrahedral units. As a result, the real
Spherical Averages on Regular and Semiregular Graphs
Douma, Femke
2008-01-01
In 1966, P. Guenther proved the following result: Given a continuous function f on a compact surface M of constant curvature -1 and its periodic lift g to the universal covering, the hyperbolic plane, then the averages of the lift g over increasing spheres converge to the average of the function f over the surface M. In this article, we prove similar results for functions on the vertices and edges of regular and semiregular graphs, with special emphasis on the convergence rate. We also consid...
Model averaging and muddled multimodel inferences
Cade, Brian S.
2015-01-01
Three flawed practices associated with model averaging coefficients for predictor variables in regression models commonly occur when making multimodel inferences in analyses of ecological data. Model-averaged regression coefficients based on Akaike information criterion (AIC) weights have been recommended for addressing model uncertainty but they are not valid, interpretable estimates of partial effects for individual predictors when there is multicollinearity among the predictor variables. Multicollinearity implies that the scaling of units in the denominators of the regression coefficients may change across models such that neither the parameters nor their estimates have common scales, therefore averaging them makes no sense. The associated sums of AIC model weights recommended to assess relative importance of individual predictors are really a measure of relative importance of models, with little information about contributions by individual predictors compared to other measures of relative importance based on effects size or variance reduction. Sometimes the model-averaged regression coefficients for predictor variables are incorrectly used to make model-averaged predictions of the response variable when the models are not linear in the parameters. I demonstrate the issues with the first two practices using the college grade point average example extensively analyzed by Burnham and Anderson. I show how partial standard deviations of the predictor variables can be used to detect changing scales of their estimates with multicollinearity. Standardizing estimates based on partial standard deviations for their variables can be used to make the scaling of the estimates commensurate across models, a necessary but not sufficient condition for model averaging of the estimates to be sensible. A unimodal distribution of estimates and valid interpretation of individual parameters are additional requisite conditions. The standardized estimates or equivalently the
Directory of Open Access Journals (Sweden)
Hana Šejnohová
2005-01-01
Full Text Available During the years 1993–2001 the monitoring of the soil surface fauna was carried out in a floodplain fo- rest in the Ranšpurk National Nature Reserve (south Moravia. The harvestmen assemblages fluctuation is described in detail in this paper. The method of pitfall traps was used. A total of 3174 individuals of seven harvestmen species were collected. The species composition was very similar to other research results from the southern Moravian floodplain forest. Only the dominance values differ from the values in the other localities. All of the registered species prefer moisture and shadow places. The highest abundance was observed in Astrobunus laevipes (Canestrini, 1872, Nemastoma lugubre (Müller, 1776, Oligolophus tridens (C. L. Koch, 1936 and Rilaena triangularis (Herbst, 1799. The dynamics of harvestmen occurrence during the year had a different development than in other groups of invertebrates. Harvestmen mostly occurred in pitfall traps in autumn and winter months. The highest abundance of harvestmen in traps was observed in December and January. In July 1997, disastrous flood affected all groups of invertebrates. The flood had a minimal impact on the abundance of harvestmen in pitfall traps.
Iungo, Giacomo Valerio; Camarri, Simone; Ciri, Umberto; El-Asha, Said; Leonardi, Stefano; Rotea, Mario A.; Santhanagopalan, Vignesh; Viola, Francesco; Zhan, Lu
2016-11-01
Site conditions, such as topography and local climate, as well as wind farm layout strongly affect performance of a wind power plant. Therefore, predictions of wake interactions and their effects on power production still remain a great challenge in wind energy. For this study, an onshore wind turbine array was monitored through lidar measurements, SCADA and met-tower data. Power losses due to wake interactions were estimated to be approximately 4% and 2% of the total power production under stable and convective conditions, respectively. This dataset was then leveraged for the calibration of a data driven RANS (DDRANS) solver, which is a compelling tool for prediction of wind turbine wakes and power production. DDRANS is characterized by a computational cost as low as that for engineering wake models, and adequate accuracy achieved through data-driven tuning of the turbulence closure model. DDRANS is based on a parabolic formulation, axisymmetry and boundary layer approximations, which allow achieving low computational costs. The turbulence closure model consists in a mixing length model, which is optimally calibrated with the experimental dataset. Assessment of DDRANS is then performed through lidar and SCADA data for different atmospheric conditions. This material is based upon work supported by the National Science Foundation under the I/UCRC WindSTAR, NSF Award IIP 1362033.
On flux terms in volume averaging
Chu, S.G.; Prosperetti, Andrea
2016-01-01
This note examines the modeling of non-convective fluxes (e.g., stress, heat flux and others) as they appear in the general, unclosed form of the volume-averaged equations of multiphase flows. By appealing to the difference between slowly and rapidly varying quantities, it is shown that the natural
Conceptual Analysis of System Average Water Stability
Zhang, H.
2016-12-01
Averaging over time and area, the precipitation in an ecosystem (SAP - system average precipitation) depends on the average surface temperature and relative humidity (RH) in the system if uniform convection is assumed. RH depends on the evapotranspiration of the system (SAE - system average evapotranspiration). There is a non-linear relationship between SAP and SAE. Studying this relationship can lead mechanistic understanding of the ecosystem health status and trend under different setups. If SAP is higher than SAE, the system will have a water runoff which flows out through rivers. If SAP is lower than SAE, irrigation is needed to maintain the vegetation status. This presentation will give a conceptual analysis of the stability in this relationship under different assumed areas, water or forest coverages, elevations and latitudes. This analysis shows that desert is a stable system. Water circulation in basins is also stabilized at a specific SAP based on the basin profile. It further shows that deforestation will reduce SAP, and can flip the system to an irrigation required status. If no irrigation is provided, the system will automatically reduce to its stable point - desert, which is extremely difficult to turn around.
A singularity theorem based on spatial averages
Indian Academy of Sciences (India)
cosmological models, but using purely spatial averages. As remarked at the end of the previous subsection, all known non-singular models were 'cosmological' in the sense that they could not describe a finite star surrounded by a surface of vanishing pressure. However, it can certainly happen that (say) the energy density ...
Cryo-Electron Tomography and Subtomogram Averaging.
Wan, W; Briggs, J A G
2016-01-01
Cryo-electron tomography (cryo-ET) allows 3D volumes to be reconstructed from a set of 2D projection images of a tilted biological sample. It allows densities to be resolved in 3D that would otherwise overlap in 2D projection images. Cryo-ET can be applied to resolve structural features in complex native environments, such as within the cell. Analogous to single-particle reconstruction in cryo-electron microscopy, structures present in multiple copies within tomograms can be extracted, aligned, and averaged, thus increasing the signal-to-noise ratio and resolution. This reconstruction approach, termed subtomogram averaging, can be used to determine protein structures in situ. It can also be applied to facilitate more conventional 2D image analysis approaches. In this chapter, we provide an introduction to cryo-ET and subtomogram averaging. We describe the overall workflow, including tomographic data collection, preprocessing, tomogram reconstruction, subtomogram alignment and averaging, classification, and postprocessing. We consider theoretical issues and practical considerations for each step in the workflow, along with descriptions of recent methodological advances and remaining limitations. © 2016 Elsevier Inc. All rights reserved.
Bayesian Averaging is Well-Temperated
DEFF Research Database (Denmark)
Hansen, Lars Kai
2000-01-01
Bayesian predictions are stochastic just like predictions of any other inference scheme that generalize from a finite sample. While a simple variational argument shows that Bayes averaging is generalization optimal given that the prior matches the teacher parameter distribution the situation...
Reliability Estimates for Undergraduate Grade Point Average
Westrick, Paul A.
2017-01-01
Undergraduate grade point average (GPA) is a commonly employed measure in educational research, serving as a criterion or as a predictor depending on the research question. Over the decades, researchers have used a variety of reliability coefficients to estimate the reliability of undergraduate GPA, which suggests that there has been no consensus…
Full averaging of fuzzy impulsive differential inclusions
Directory of Open Access Journals (Sweden)
Natalia V. Skripnik
2010-09-01
Full Text Available In this paper the substantiation of the method of full averaging for fuzzy impulsive differential inclusions is studied. We extend the similar results for impulsive differential inclusions with Hukuhara derivative (Skripnik, 2007, for fuzzy impulsive differential equations (Plotnikov and Skripnik, 2009, and for fuzzy differential inclusions (Skripnik, 2009.
Quantum Averaging of Squeezed States of Light
DEFF Research Database (Denmark)
Squeezing has been recognized as the main resource for quantum information processing and an important resource for beating classical detection strategies. It is therefore of high importance to reliably generate stable squeezing over longer periods of time. The averaging procedure for a single...
Bootstrapping Density-Weighted Average Derivatives
DEFF Research Database (Denmark)
Cattaneo, Matias D.; Crump, Richard K.; Jansson, Michael
Employing the "small bandwidth" asymptotic framework of Cattaneo, Crump, and Jansson (2009), this paper studies the properties of a variety of bootstrap-based inference procedures associated with the kernel-based density-weighted averaged derivative estimator proposed by Powell, Stock, and Stoker...
A dynamic analysis of moving average rules
Chiarella, C.; He, X.Z.; Hommes, C.H.
2006-01-01
The use of various moving average (MA) rules remains popular with financial market practitioners. These rules have recently become the focus of a number empirical studies, but there have been very few studies of financial market models where some agents employ technical trading rules of the type
Average Costs versus Net Present Value
E.A. van der Laan (Erwin); R.H. Teunter (Ruud)
2000-01-01
textabstractWhile the net present value (NPV) approach is widely accepted as the right framework for studying production and inventory control systems, average cost (AC) models are more widely used. For the well known EOQ model it can be verified that (under certain conditions) the AC approach gives
Directory of Open Access Journals (Sweden)
Yuli Darni
2011-12-01
Full Text Available The article reported the laboratory experiment to obtain the optimal condition of particle size and Reynold Number of bioplastic film based on the plastic package standard of High Density Polyethylene (HDPE. Particle sizes of starch were varied at 63, 90, 106, 600, and 1000 micron, and the mixing rate were changes at 190, 252, 313, 375, and 437 rpm. The concentration of chitosan and gliserol added to solution were set as constant variable as 20 and 10 wt %, respectively. The temperature of gelatinitation was also fixed at 95OC. The fabricated of bioplastic film were characterized for mechanical property such as tensile strength, elongation at break and Modulus Young by using a Universal Testing Machine. The morphology of film sheets were observed by using a scanning electron microscopy (SEM. Moreover, the obtained film was also investigated for water uptake parameter. The result showed that the mechanical properties were improve by increasing mixing rate at smallest particle sizes of starch. The water uptakes shows decrease at hight mixing rate. SEM images showed that the morphology of bioplastic was almost simmilar to the morphology of HDPE. The optimum condition was found that the best film was obtained at particle size of starch 63 micron, Reynold Number of 959, with mixing rate of 375 rpm. The mechanical value at best condition was 19.27%, 757.046 Mpa, and 142.875 for elongation, Modulus Young, and tensile strength, respectively. Keywords: bioplastic, reynold Number, starch, sorgum
Flowing of supersonic underexpanded micro-jets in the range of moderate Reynolds numbers
Mironov, S. G.; Aniskin, V. M.; Maslov, A. A.
2017-10-01
The paper presents new experimental results on the simulation of supersonic underexpanded micro-jets by macro-jet in the range of moderate Reynolds numbers of air outflow from the nozzle. A correlation is shown between the variations in the Pitot pressure in the model micro-jet with variations in the length of the supersonic core of real the micro-jets. The results of experiments on the effect of humidity on the pulsation of mass flow rate in a micro-jet are presented.
Gomez, T; Flutet, V; Sagaut, P
2009-03-01
An exact relationship for the local skin friction is derived for the compressible turbulent wall-bounded flow (channel, pipe, flat plate). This expression is an extension of the compressible case of that derived by Fukagata [Phys. Fluids 14, L73 (2002)] in the case of incompressible wall-bounded flows. This decomposition shows that the skin friction can be interpreted as the contribution of four physical processes, i.e., laminar, turbulent, compressible, and a fourth coming from the interaction between turbulence and compressibility. Compressible numerical simulations show that, even at Mach number M=2 , the main contribution comes from the turbulence, i.e., the Reynolds stress term.
On the application of reynolds theory to thermo-piezo-viscous lubrication in oil hydraulics
DEFF Research Database (Denmark)
Johansen, Per; Roemer, Daniel Beck; Andersen, Torben O.
2015-01-01
The efficiency of fluid power motors and pumps is a subject to research, which has generated numerous publications during the last three decades. The main incentives for this research are optimization of reliability and efficiency through the study of loss and wear mechanisms, which are very...... difficult to study experimentally, whereby modeling and simulation are necessary. A common approach to theoretical investigation of the pressure generated in the lubricated joints is the use of Reynolds equation, in which the oil viscosity is modelled with dependency of both pressure and temperature...
Reynolds and Maxwell stress measurements in the reversed field pinch experiment Extrap-T2R
Vianello, N.; Antoni, V.; Spada, E.; Spolaore, M.; Serianni, G.; Cavazzana, R.; Bergsåker, H.; Cecconello, M.; Drake, J. R.
2005-08-01
The complete Reynolds stress (RS) has been measured in the edge region of the Extrap-T2R reversed field pinch experiment. The RS exhibits a strong gradient in the region where a high E × B shear takes place. Experimental results show this gradient to be almost entirely due to the electrostatic contribution. This has been interpreted as experimental evidence of flow generation via turbulence mechanism. The scales involved in flow generation are deduced from the frequency decomposition of RS tensor. They are found related to magnetohydrodynamic activity but are different with respect to the scales responsible for turbulent transport.
McDowell, Robert C.; Harrison, Richard W.; Lagueux, Kerry M.
2000-01-01
The geology of the Powder Mill Ferry 7 1/2-minute quadrangle , Shannon and Reynolds Counties, Missouri was mapped from 1997 through 1998 as part of the Midcontinent Karst Systems and Geologic Mapping Project, Eastern Earth Surface Processes Team. The map supports the production of a geologic framework that will be used in hydrogeologic investigations related to potential lead and zinc mining in the Mark Twain National Forest adjacent to the Ozark National Scenic Riverways (National Park Service). Digital geologic coverages will be used by other federal and state agencies in hydrogeologic analyses of the Ozark karst system and in ecological models.
ANALYSIS OF THE FACTORS AFFECTING THE AVERAGE
Directory of Open Access Journals (Sweden)
Carmen BOGHEAN
2013-12-01
Full Text Available Productivity in agriculture most relevantly and concisely expresses the economic efficiency of using the factors of production. Labour productivity is affected by a considerable number of variables (including the relationship system and interdependence between factors, which differ in each economic sector and influence it, giving rise to a series of technical, economic and organizational idiosyncrasies. The purpose of this paper is to analyse the underlying factors of the average work productivity in agriculture, forestry and fishing. The analysis will take into account the data concerning the economically active population and the gross added value in agriculture, forestry and fishing in Romania during 2008-2011. The distribution of the average work productivity per factors affecting it is conducted by means of the u-substitution method.
Numerical and experimental research on pentagonal cross-section of the averaging Pitot tube
Zhang, Jili; Li, Wei; Liang, Ruobing; Zhao, Tianyi; Liu, Yacheng; Liu, Mingsheng
2017-07-01
Averaging Pitot tubes have been widely used in many fields because of their simple structure and stable performance. This paper introduces a new shape of the cross-section of an averaging Pitot tube. Firstly, the structure of the averaging Pitot tube and the distribution of pressure taps are given. Then, a mathematical model of the airflow around it is formulated. After that, a series of numerical simulations are carried out to optimize the geometry of the tube. The distribution of the streamline and pressures around the tube are given. To test its performance, a test platform was constructed in accordance with the relevant national standards and is described in this paper. Curves are provided, linking the values of flow coefficient with the values of Reynolds number. With a maximum deviation of only ±3%, the results of the flow coefficient obtained from the numerical simulations were in agreement with those obtained from experimental methods. The proposed tube has a stable flow coefficient and favorable metrological characteristics.
Thomareis, Nikitas; Papadakis, George
2017-01-01
Direct numerical simulations of the flow field around a NACA 0012 airfoil at Reynolds number 50 000 and angle of attack 5° with 3 different trailing edge shapes (straight, blunt, and serrated) have been performed. Both time-averaged flow characteristics and the most dominant flow structures and their frequencies are investigated using the dynamic mode decomposition method. It is shown that for the straight trailing edge airfoil, this method can capture the fundamental as well as the subharmonic of the Kelvin-Helmholtz instability that develops naturally in the separating shear layer. The fundamental frequency matches well with relevant data in the literature. The blunt trailing edge results in periodic vortex shedding, with frequency close to the subharmonic of the natural shear layer frequency. The shedding, resulting from a global instability, has an upstream effect and forces the separating shear layer. Due to forcing, the shear layer frequency locks onto the shedding frequency while the natural frequency (and its subharmonic) is suppressed. The presence of serrations in the trailing edge creates a spanwise pressure gradient, which is responsible for the development of a secondary flow pattern in the spanwise direction. This pattern affects the mean flow in the near wake. It can explain an unexpected observation, namely, that the velocity deficit downstream of a trough is smaller than the deficit after a protrusion. Furthermore, the insertion of serrations attenuates the energy of vortex shedding by de-correlating the spanwise coherence of the vortices. This results in weaker forcing of the separating shear layer, and both the subharmonics of the natural frequency and the shedding frequency appear in the spectra.
Directory of Open Access Journals (Sweden)
Takayuki Matsunuma
2012-01-01
Full Text Available Active flow control using dielectric barrier discharge (DBD plasma actuators was investigated to reattach the simulated boundary layer separation on the suction surface of a turbine blade at low Reynolds number, Re = 1.7 × 104. The flow separation is induced on a curved plate installed in the test section of a low-speed wind tunnel. Particle image velocimetry (PIV was used to obtain instantaneous and time-averaged two-dimensional velocity measurements. The amplitude of input voltage for the plasma actuator was varied from ±2.0 kV to ±2.8 kV. The separated flow reattached on the curved wall when the input voltage was ±2.4 kV and above. The displacement thickness of the boundary layer near the trailing edge decreased by 20% at ±2.0 kV. The displacement thickness was suddenly reduced as much as 56% at ±2.2 kV, and it was reduced gradually from ±2.4 kV to ±2.8 kV (77% reduction. The total pressure loss coefficient, estimated from the boundary layer displacement thickness and momentum thickness, was 0.172 at the baseline (actuator off condition. The total pressure loss was reduced to 0.107 (38% reduction at ±2.2 kV and 0.078 (55% reduction at ±2.8 kV.
Average Light Intensity Inside a Photobioreactor
Directory of Open Access Journals (Sweden)
Herby Jean
2011-01-01
Full Text Available For energy production, microalgae are one of the few alternatives with high potential. Similar to plants, algae require energy acquired from light sources to grow. This project uses calculus to determine the light intensity inside of a photobioreactor filled with algae. Under preset conditions along with estimated values, we applied Lambert-Beer's law to formulate an equation to calculate how much light intensity escapes a photobioreactor and determine the average light intensity that was present inside the reactor.
The Average Velocity in a Queue
Frette, Vidar
2009-01-01
A number of cars drive along a narrow road that does not allow overtaking. Each driver has a certain maximum speed at which he or she will drive if alone on the road. As a result of slower cars ahead, many cars are forced to drive at speeds lower than their maximum ones. The average velocity in the queue offers a non-trivial example of a mean…
Unscrambling The "Average User" Of Habbo Hotel
Directory of Open Access Journals (Sweden)
Mikael Johnson
2007-01-01
Full Text Available The “user” is an ambiguous concept in human-computer interaction and information systems. Analyses of users as social actors, participants, or configured users delineate approaches to studying design-use relationships. Here, a developer’s reference to a figure of speech, termed the “average user,” is contrasted with design guidelines. The aim is to create an understanding about categorization practices in design through a case study about the virtual community, Habbo Hotel. A qualitative analysis highlighted not only the meaning of the “average user,” but also the work that both the developer and the category contribute to this meaning. The average user a represents the unknown, b influences the boundaries of the target user groups, c legitimizes the designer to disregard marginal user feedback, and d keeps the design space open, thus allowing for creativity. The analysis shows how design and use are intertwined and highlights the developers’ role in governing different users’ interests.
AVERAGE SCORE OF THE UNIFIED STATE EXAMINATION
Directory of Open Access Journals (Sweden)
L. M. Nurieva
2017-01-01
Full Text Available Introduction. Summing up the results of the Unified State Exam (USE is traditionally based on comparing the average scores for institutions or territories, without taking into account what the indicator of the quality of education really represents.The aim of the article is to clarify the content «average score» on the example of the Mathematics federal testing results.Methodology and research methods. The methodology of comprehensive analysis is used, including the methods of comparative and statistical data analysis published following the exam results. As well, the parallel analysis of data used in the researches of the National Research University «The Higher School of Economics» (HSE was conducted.Results and scientific novelty. It is found out that the average score in the Unified State Exam in mathematics largely depends on peculiarities of testing and assessment materials, a scoring system of leveling nature and results of training students for solving simple problems.Practical significance. The authors suppose that the study findings will contribute to the improvement of methods and technologies of carrying the Unified State Exam.
On Backus average for generally anisotropic layers
Bos, Len; Slawinski, Michael A; Stanoev, Theodore
2016-01-01
In this paper, following the Backus (1962) approach, we examine expressions for elasticity parameters of a homogeneous generally anisotropic medium that is long-wave-equivalent to a stack of thin generally anisotropic layers. These expressions reduce to the results of Backus (1962) for the case of isotropic and transversely isotropic layers. In over half-a-century since the publications of Backus (1962) there have been numerous publications applying and extending that formulation. However, neither George Backus nor the authors of the present paper are aware of further examinations of mathematical underpinnings of the original formulation; hence, this paper. We prove that---within the long-wave approximation---if the thin layers obey stability conditions then so does the equivalent medium. We examine---within the Backus-average context---the approximation of the average of a product as the product of averages, and express it as a proposition in terms of an upper bound. In the presented examination we use the e...
Average neutron detection efficiency for DEMON detectors
Zhang, S.; Lin, W.; Rodrigues, M. R. D.; Huang, M.; Wada, R.; Liu, X.; Zhao, M.; Jin, Z.; Chen, Z.; Keutgen, T.; Kowalski, S.; Hagel, K.; Barbui, M.; Bonasera, A.; Bottosso, C.; Materna, T.; Natowitz, J. B.; Qin, L.; Sahu, P. K.; Schmidt, K. J.; Wang, J.
2013-05-01
The neutron detection efficiency of a DEMON detector, averaged over the whole volume, was calculated using GEANT and applied to determine neutron multiplicities in an intermediate heavy ion reaction. When a neutron source is set at a distance of about 1 m from the front surface of the detector, the average efficiency, ɛav, is found to be significantly lower (20-30%) than the efficiency measured at the center of the detector, ɛ0. In the GEANT simulation the ratio R=ɛav/ɛ0 was calculated as a function of neutron energy. The experimental central efficiency multiplied by R was then used to determine the average efficiency. The results were applied to a study of the 64Zn+112Sn reaction at 40 A MeV which employed 16 DEMON detectors. The neutron multiplicity was extracted using a moving source fit. The derived multiplicities are compared well with those determined using the neutron ball in the NIMROD detector array in a separate experiment. Both are in good agreement with multiplicities predicted by a transport model calculation using an antisymmetric molecular dynamics (AMD) model code.
Disk-averaged synthetic spectra of Mars.
Tinetti, Giovanna; Meadows, Victoria S; Crisp, David; Fong, William; Velusamy, Thangasamy; Snively, Heather
2005-08-01
The principal goal of the NASA Terrestrial Planet Finder (TPF) and European Space Agency's Darwin mission concepts is to directly detect and characterize extrasolar terrestrial (Earthsized) planets. This first generation of instruments is expected to provide disk-averaged spectra with modest spectral resolution and signal-to-noise. Here we use a spatially and spectrally resolved model of a Mars-like planet to study the detectability of a planet's surface and atmospheric properties from disk-averaged spectra. We explore the detectability as a function of spectral resolution and wavelength range, for both the proposed visible coronograph (TPFC) and mid-infrared interferometer (TPF-I/Darwin) architectures. At the core of our model is a spectrum-resolving (line-by-line) atmospheric/surface radiative transfer model. This model uses observational data as input to generate a database of spatially resolved synthetic spectra for a range of illumination conditions and viewing geometries. The model was validated against spectra recorded by the Mars Global Surveyor-Thermal Emission Spectrometer and the Mariner 9-Infrared Interferometer Spectrometer. Results presented here include disk-averaged synthetic spectra, light curves, and the spectral variability at visible and mid-infrared wavelengths for Mars as a function of viewing angle, illumination, and season. We also considered the differences in the spectral appearance of an increasingly ice-covered Mars, as a function of spectral resolution, signal-to-noise and integration time for both TPF-C and TPFI/ Darwin.