WorldWideScience

Sample records for rank prize lecture

  1. Full implementation of rank-dependent prizes

    DEFF Research Database (Denmark)

    Midjord, Rune

    2013-01-01

    A manager/mechanism designer must allocate a set of money prizes ($1,$2,…,$n) between n agents working in a team. The agents know the state, i.e., who contributed most, second most, etc. The agents’ preferences over prizes are state independent. We incorporate the possibility that the manager knows...... the state with a tiny probability and present a simple mechanism that uniquely awards prizes that respect the true state....

  2. Muller's Nobel Prize Lecture: when ideology prevailed over science.

    Science.gov (United States)

    Calabrese, Edward J

    2012-03-01

    This paper extends and confirms the report of Calabrese (Calabrese, E. J. (2011b). Muller's Nobel Lecture on dose-response for ionizing radiation: Ideology or science? Arch. Toxicol. 85, 1495-1498) that Hermann J. Muller knowingly made deceptive comments in his 1946 Nobel Prize Lecture (Muller, H. J. (1946). Nobel Prize Lecture. Stockholm, Sweden. Available at http://www.nobelprize.org/. Accessed December 12) concerning the dose-response. Supporting a linearity perspective, Muller stated there is "no escape from the conclusion that there is no threshold" while knowing the results of a recent study by Ernst Caspari and Curt Stern contradicted these comments. Recently uncovered private correspondence between Muller and Stern reveals Muller's scientific assessment of the Caspari and Stern manuscript in a letter from Muller to Stern 5 weeks (14 January 1947) after his Nobel Prize Lecture of 12 December 1946. Muller indicated that the manuscript was of acceptable scientific quality; he indicated the manuscript should be published, but the findings needed replication because it significantly challenged the linearity hypothesis. These findings complement the previous letter (12 November 1946 letter from Muller to Stern), which revealed that Muller received the Caspari and Stern manuscript, recognized it as significant, and recommended its replication 5 weeks before his Nobel Prize Lecture. Muller therefore supported this position immediately before and after his Nobel Prize Lecture. Muller's opinions on the Caspari and Stern manuscript therefore had not changed during the time leading up to his Lecture, supporting the premise that his Lecture comments were deceptive. These findings are of historical and practical significance because Muller's comments were a notable contributory factor, changing how risks would be assessed for carcinogens (i.e., changing from a threshold to a linear model) throughout the 20th century to the present.

  3. Causes and Effects in Macroeconomics: 2011 Nobel Prize Lecture in Economic Sciences

    Directory of Open Access Journals (Sweden)

    Shlair Abdulkhaleq Al-Zanganee

    2015-12-01

    Full Text Available Noble Laureates Thomas Sargent and Christopher Sims have been granted the 2011 Noble Prize in economic sciences in appreciation of their empirical research on causes and effects in macroeconomics. The controversy on causality in macroeconomics was discussed in both of Sargent’s and Sims’s 2011 Prize lectures. While Sargent attempts to use the economic theory to interpret some historical events in order to gain insights on some contemporary issues, such as sovereign defaults, federal bailouts, and the coordination of monetary and fiscal policies, Sims is emphasizing the importance of large-scale economic models and calling for more research to be done in that area.

  4. Julius Edgar Lilienfeld Prize: Lilienfeld Prize Lecture: Emergent Behavior in Quantum Matter

    Science.gov (United States)

    Pines, David

    We live in an emergent universe in which interactions between the basic building blocks of matter and their environment give rise to unpredicted and unexpected emergent behavior at every scale. As physicists we seek to identify the organizing principles responsible for that behavior, construct soluble models that incorporate these, and explain experiment. In this lecture, I illustrate this approach to understanding emergent behavior in quantum matter through three examples: collective modes in electron, helium, and nuclear liquids; the emergence of superconductivity in conventional and unconventional superconductors, nuclei, and neutron stars; and the emergence of heavy electrons in Kondo lattice materials.

  5. Nobel Prize Recipient Eric Betzig Presents Lecture on Efforts to Improve High-Resolution Microscopy | Poster

    Science.gov (United States)

    Eric Betzig, Ph.D., a 2014 recipient of the Nobel Prize in Chemistry and a scientist at Janelia Research Campus (JRC), Howard Hughes Medical Institute, in Ashburn, Va., visited NCI at Frederick on Sept. 10 to present a Distinguished Scientist lecture and discuss the latest high-resolution microscopy techniques. Betzig co-invented photoactivation localization microscopy (PALM) in collaboration with scientists at NIH. PALM achieves 10-fold improvement in spatial resolution of cells, going from the resolution limit of approximately 250 nm in standard optical microscopy down to approximately 20 nm, thus producing a so-called “super-resolution” image. Spatial resolution refers to the clarity of an image or, in other words, the smallest details that can be observed from an image.

  6. Lecture by the winner of the 2007 Nobel Prize for physics

    CERN Multimedia

    2007-01-01

    Professor Albert Fert, who has just been awarded the Nobel Prize for physics for his work on giant magneto-resistance and spintronics, will give a lecture at the University of Geneva on 16 November on this booming field of science. (c) CNRS Photothèque - C. LebedinskyOn 9 October, the 2007 Nobel Prize for physics was jointly awarded to Albert Fert of the CNRS and Peter Grünberg of the Jülich Research Centre for their simultaneous and independent discovery of giant magneto-resistance (GMR) in 1988. This discovery had a significant impact in the fields of information technology and communications as it was rapidly used to develop extremely sensitive hard disk read-out heads that are capable of reading information stored at very high densities, thereby allowing further progress in the miniaturisation of data-storage devices. Since the first GMR read-out head was launched in 1997, the technology has become the standard in the m...

  7. Dannie Heineman Prize for Mathematical Physics Lecture: Understanding Nonequilibrium via Rare Fluctuations

    Science.gov (United States)

    Jona-Lasinio, Giovanni

    2012-02-01

    Irreversible processes are a hot subject in statistical mechanics. During the last decade through the effort of several people, including the recipient of the prize and his collaborators, a progress in understanding stationary nonequilibrium states has been achieved. The key has been the study of rare fluctuations. The talk will review some basic ideas, results and perspectives.

  8. Abraham Pais Prize Lecture: Shifting Problems and Boundaries in the History of Modern Physics

    Science.gov (United States)

    Nye, Mary-Jo

    A long established category of study in the history of science is the ``history of physical sciences.'' It is a category that immediately begs the question of disciplinary boundaries for the problems and subjects addressed in historical inquiry. As a historian of the physical sciences, I often have puzzled over disciplinary boundaries and the means used to create or justify them. Scientists most often have been professionally identified with specific institutionalized fields since the late 19th century, but the questions they ask and the problems they solve are not neatly carved up by disciplinary perimeters. Like institutional departments or professorships, the Nobel Prizes in the 20th century often have delineated the scope of ``Physics'' or ``Chemistry'' (and ``Physiology or Medicine''), but the Prizes do not reflect disciplinary rigidity, despite some standard core subjects. In this paper I examine trends in Nobel Prize awards that indicate shifts in problem solving and in boundaries in twentieth century physics, tying those developments to changing themes in the history of physics and physical science in recent decades.

  9. Colliding worlds: A journey in time and space through the solar system (Farinella Prize Lecture)

    Science.gov (United States)

    Marchi, S.

    2017-09-01

    The evolution of the interiors, surfaces, and atmospheres of solid bodies in the solar system is affected by interplanetary collisions. From Mercury to the outskirts of the solar system, collisions with leftover planetesimals -asteroids, comets and their debris- provide a primary evolutionary process. Impact craters mark this evolution and provide a diagnostic tool, which coupled with modeling and, when possible, sample analysis, allow us to unravel the ancient history of the solar system. In this prize talk, I will present a few selected cutting-edge research topics at the frontier between modeling and space exploration that without any doubt would have deeply interested the curious mind of Paolo Farinella.

  10. Piet Mondrian's trees and the evolution in understanding multiple sclerosis, Charcot Prize Lecture 2011

    NARCIS (Netherlands)

    Steinman, L.; Axtell, R.C.; Barbieri, D.; Bhat, R.; Brownell, S.E.; Jong, B.A. de; Dunn, S.E.; Grant, J.L.; Han, M.H.; Ho, P.P.; Kuipers, H.F.; Kurnellas, M.P.; Ousman, S.S.; Rothbard, J.B.

    2013-01-01

    Four questions were posed about multiple sclerosis (MS) at the 2011 Charcot Lecture, Oct. 22, 2011. 1. The Male/Female Disparity: Why are women developing MS so much more frequently than men? 2. Neuronal and Glial Protection: Are there guardian molecules that protect the nervous system in MS? 3.

  11. A lecture by Saul Perlmutter, winner of the 2011 Nobel prize in physics

    CERN Multimedia

    2011-01-01

    The CNRS National Institute of Nuclear Physics and Particle Physics (IN2P3), Pierre et Marie Curie University and the Laboratory of Nuclear and High-energy Physics (LPNHE) are happy to invite you to a talk by Nobel laureate Saul Perlmutter.   Perlmutter shared the 2011 Nobel prize in physics "for the discovery of the accelerating expansion of the Universe through observations of distant supernovae." He will give a public talk in Paris on 17 December at 5pm: "Supernovae, Dark Energy, and the Accelerating Universe" Amphithéâtre Farabeuf des Cordeliers 21, rue de l’école de Médecine 75006 Paris Free entrance (places are limited) and live translation available.

  12. The Sharpey-Schafer prize lecture: nucleus tractus solitarii: integrating structures.

    Science.gov (United States)

    PATON, J F

    1999-09-01

    Presently, many researchers have adopted a reductionistic approach to physiology. Specifically, this involves studies on acutely isolated or cultured cells. While this is essential for our understanding of important cellular and subcellular mechanisms, it should not be forgotten that physiology is about the function of an integrating body. One view point is that definitive interpretations can only be made by crossing boundaries of physiology from the molecular/ cellular to the systems/behavioural level. An aim of this lecture will stress the importance of a multidisciplinary approach to physiology, that is, 'putting the cell back into the system'. The lecture attempts to demonstrate why this is important for enhancing the functional significance and relevance of physiological data as well as for validating predictions.

  13. Irving Langmuir Prize Lecture - A predictive theory of transition metal surface catalysis

    Science.gov (United States)

    Norskov, Jens

    2015-03-01

    The lecture will outline a theory of heterogeneous catalysis that allows a detailed understanding of elementary chemical processes at transition metal surfaces and singles out the most important parameters determining catalytic activity and selectivity. It will be shown how scaling relations allow the identification of descriptors of catalytic activity and how they can be used to construct activity and selectivity maps. The maps can be used to define catalyst design rules and examples of their use will be given.

  14. Piet Mondrian's trees and the evolution in understanding multiple sclerosis, Charcot Prize Lecture 2011.

    Science.gov (United States)

    Steinman, Lawrence; Axtell, Robert C; Barbieri, Donald; Bhat, Roopa; Brownell, Sara E; de Jong, Brigit A; Dunn, Shannon E; Grant, Jacqueline L; Han, May H; Ho, Peggy P; Kuipers, Hedwich F; Kurnellas, Michael P; Ousman, Shalina S; Rothbard, Jonathan B

    2013-01-01

    Four questions were posed about multiple sclerosis (MS) at the 2011 Charcot Lecture, Oct. 22, 2011. 1. The Male/Female Disparity: Why are women developing MS so much more frequently than men? 2. Neuronal and Glial Protection: Are there guardian molecules that protect the nervous system in MS? 3. Predictive Medicine: With all the approved drugs, how can we rationally decide which one to use? 4. The Precise Scalpel vs. the Big Hammer for Therapy: Is antigen-specific therapy for demyelinating disease possible? To emphasize how our views on the pathogenesis and treatment of MS are evolving, and given the location of the talk in Amsterdam, Piet Mondrian's progressive interpretations of trees serve as a heuristic.

  15. Transmission as a basic process in microbial biology. Lwoff Award Prize Lecture.

    Science.gov (United States)

    Baquero, Fernando

    2017-11-01

    Transmission is a basic process in biology and evolution, as it communicates different biological entities within and across hierarchical levels (from genes to holobionts) both in time and space. Vertical descent, replication, is transmission of information across generations (in the time dimension), and horizontal descent is transmission of information across compartments (in the space dimension). Transmission is essentially a communication process that can be studied by analogy of the classic information theory, based on 'emitters', 'messages' and 'receivers'. The analogy can be easily extended to the triad 'emigration', 'migration' and 'immigration'. A number of causes (forces) determine the emission, and another set of causes (energies) assures the reception. The message in fact is essentially constituted by 'meaningful' biological entities. A DNA sequence, a cell and a population have a semiotic dimension, are 'signs' that are eventually recognized (decoded) and integrated by receiver biological entities. In cis-acting or unenclosed transmission, the emitters and receivers correspond to separated entities of the same hierarchical level; in trans-acting or embedded transmission, the information flows between different, but frequently nested, hierarchical levels. The result (as in introgressive events) is constantly producing innovation and feeding natural selection, influencing also the evolution of transmission processes. This review is based on the concepts presented at the André Lwoff Award Lecture in the FEMS Microbiology Congress in Maastricht in 2015. © FEMS 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  16. Aneesu-Rahman Prize Lecture: The ``sign problem'' in Quantum Monte Carlo

    Science.gov (United States)

    Ceperley, D. M.

    1998-03-01

    Quantum simulation methods have been quite successful in giving exact results for certain systems, primarily bosons(Ceperley, D.M. , Rev. Mod. Phys. 67), 279 (1995).. Use of the same techniques in general quantum systems leads to the so-called ``sign problem''; the results are correct but the methods are very inefficient. There are two important questions to ask of a proposed method. Given enough computer time can arbitrarily accurate results be obtained? If so, how long does it take to achieve a given error? There are several methods (released-node or transient estimate) that are exact; the difficulty is in finding a method which also scales well with the number of quantum degrees of freedom. Exact methods, in general, scale exponentially with the number of fermions and in the inverse temperature (or accuracy). At root, the fact that wavefunction is complex or changes sign, gives rise to the poor scaling and the ``sign problem.'' It is not the fermion nature of the system, per se, that causes the difficulty. The desired state is not the absolute ground state. Methods which cancel random walks from positive and negative regions have also been limited to quite small systems because they scale poorly. There are a variety of approximate simulation methods which do scale well, such as variational Monte Carlo, and a variety of fixed-node methods (restricted Path Integral Monte Carlo at non-zero temperature and constrained path methods for lattice models) which fix only boundary conditions not the sampling function. For many systems, the variational and fixed-node methods can be very accurate. The lecture notes and references are on my group's homepage.

  17. Dillion Medal Prize Lecture

    Science.gov (United States)

    Ganesan, Venkat

    2009-03-01

    Many aspects of polymer research have undergone a paradigm shift in the past decade, with an increased emphasis on technological applications which propose the use of materials and devices created by controlling matter from the atomic scales to the bulk commodity level. This talk will focus on multicomponent polymeric materials (block copolymers, rod-coil polymers and mixtures like polymer blends and polymer nanocomposites), which have played a central role in enabling this paradigm shift in the context of polymeric materials. In this talk, I will discuss our recent researches on developing simulation tools that can predict the structure, morphology and flow behavior of such multicomponent polymers. In contrast to conventional (``particle-based'') Monte Carlo and Molecular dynamics approaches, our methods work at a coarse-grained description of the system to predict the thermodynamics and dynamics of such multicomponent polymers. This talk will focus on an outline of the simulation strategies and present some results concerning both the equilibrium and dynamical properties of such materials.

  18. News Conference: Brecon hosts 10th teacher's conference Summer school: Science summer school heads to Crete Award: The Corti Science Prize Radioactivity: Scottish beach is no beta off Workshop: Heureka project promotes teaching Experiments: Spanish project proves that learning science can be exciting Lecture: IOP schools lecture journeys from x-rays to antimatter Correction to the news item 'Delegates experience universality' Forthcoming events

    Science.gov (United States)

    2012-01-01

    Conference: Brecon hosts 10th teacher's conference Summer school: Science summer school heads to Crete Award: The Corti Science Prize Radioactivity: Scottish beach is no beta off Workshop: Heureka project promotes teaching Experiments: Spanish project proves that learning science can be exciting Lecture: IOP schools lecture journeys from x-rays to antimatter Correction to the news item 'Delegates experience universality' Forthcoming events

  19. A Life of Learning: Nancy Siraisi. Charles Homer Haskins Prize Lecture for 2010. ACLS Occasional Paper, No. 67

    Science.gov (United States)

    American Council of Learned Societies, 2010

    2010-01-01

    Nancy Siraisi has been a prolific and leading scholar in the history of medicine and science of the Middle Ages and the Renaissance. This lecture of hers is the twenty-eighth of series of lectures named for Charles Homer Haskins, first chairman of the American Council of Learned Societies (ACLS) and himself a famed medievalist who brought…

  20. Conference on "Multidisciplinary approaches to nutritional problems". Rank Prize Lecture. Global nutrition challenges for optimal health and well-being.

    Science.gov (United States)

    Uauy, Ricardo; Corvalan, Camila; Dangour, Alan D

    2009-02-01

    Optimal health and well-being are now considered the true measures of human development. Integrated strategies for infant, child and adult nutrition are required that take a life-course perspective to achieve life-long health. The major nutrition challenges faced today include: (a) addressing the pending burden of undernutrition (low birth weight, severe wasting, stunting and Zn, retinol, Fe, iodine and folic acid deficits) affecting those individuals living in conditions of poverty and deprivation; (b) preventing nutrition-related chronic diseases (obesity, diabetes, CVD, some forms of cancer and osteoporosis) that, except in sub-Saharan Africa, are the main causes of death and disability globally. This challenge requires a life-course perspective as effective prevention starts before conception and continues at each stage of life. While death is unavoidable, premature death and disability can be postponed by providing the right amount and quality of food and by maintaining an active life; (c) delaying or avoiding, via appropriate nutrition and physical activity interventions, the functional declines associated with advancing age. To help tackle these challenges, it is proposed that the term 'malnutrition in all its forms', which encompasses the full spectrum of nutritional disorders, should be used to engender a broader understanding of global nutrition problems. This term may prove particularly helpful when interacting with policy makers and the public. Finally, a greater effort by the UN agencies and private and public development partners is called for to strengthen local, regional and international capacity to support the much needed change in policy and programme activities focusing on all forms of malnutrition with a unified agenda.

  1. George E. Pake Prize Lecture

    Science.gov (United States)

    Murray, Cherry

    2005-03-01

    Over the past decade, a combination of the changes in the regulatory environment coupled with accelerating advances in technology caused the telecommunications industry to experience first an accelerated growth `boom' followed by a major `bust' - perhaps corresponding to the worst downturn in its history. Throughout this turbulent time, Bell Lab’s parent company, Lucent, has transformed itself from a vertically integrated 38B telecomm systems company with 157k employees in 11 separate businesses into a horizontally layered, 9B network infrastructure systems integrator with 32K employees and 100 major customers. My talk will relate to how Bell Labs Research has weathered the `perfect storm', survived, and still maintains its focus on the future of telecommunications science and technology.

  2. Heroes in endocrinology: Nobel Prizes.

    Science.gov (United States)

    de Herder, Wouter W

    2014-09-01

    The Nobel Prize in Physiology or Medicine was first awarded in 1901. Since then, the Nobel Prizes in Physiology or Medicine, Chemistry and Physics have been awarded to at least 33 distinguished researchers who were directly or indirectly involved in research into the field of endocrinology. This paper reflects on the life histories, careers and achievements of 11 of them: Frederick G Banting, Roger Guillemin, Philip S Hench, Bernardo A Houssay, Edward C Kendall, E Theodor Kocher, John J R Macleod, Tadeus Reichstein, Andrew V Schally, Earl W Sutherland, Jr and Rosalyn Yalow. All were eminent scientists, distinguished lecturers and winners of many prizes and awards. © 2014 The authors.

  3. Prize Draw

    CERN Multimedia

    Staff Association

    2014-01-01

      Prize draw Go Sport vouchers 393 members of the Staff Association participated in our free prize draw in July where they could win one of the thirty Go Sport vouchers of 50 euros. The thirty winners have been contacted and can come and collect their voucher from the Staff Association Secretariat.

  4. News Conference: Physics brings the community together Training: CERN trains physics teachers Education: World conference fosters physics collaborations Lecture: Physics education live at ASE Prize: Physics teacher wins first Moore medal Festival: European presidents patronize Science on Stage festival Videoconference: Videoconference brings Durban closer to the classroom

    Science.gov (United States)

    2012-03-01

    Conference: Physics brings the community together Training: CERN trains physics teachers Education: World conference fosters physics collaborations Lecture: Physics education live at ASE Prize: Physics teacher wins first Moore medal Festival: European presidents patronize Science on Stage festival Videoconference: Videoconference brings Durban closer to the classroom

  5. Challenges & Prizes

    Science.gov (United States)

    Prize competitions are open innovation tools championed by the America COMPETES ACT that EPA and other federal agencies use to attract fresh thinkers and creative problem solvers from across the country and the world.

  6. Koshiba, Tanaka give Nobel lectures

    CERN Multimedia

    2002-01-01

    Masatoshi Kosiba and Koichi Tanaka presented lectures in English on Sunday, touching on topics ranging from particle physics, to teamwork to commemorate their reception of this year's Nobel Prize for Physics and Chemistry. The two will receive their respective prizes in an awards ceremony scheduled for Tuesday (1 page).

  7. Even the Pulitzer Prize....

    Science.gov (United States)

    Harris, Carla

    1992-01-01

    Discusses the selection process for rewarding the Pulitzer Prize in explanatory journalism. Shares Pulitzer Prize winner Jon Franklin's observations about writing competitions for students and professionals. (SR)

  8. Pulitzer Prize Speakers Enhance Credibility of San Antonio Program.

    Science.gov (United States)

    Aradillas, Elaine

    1994-01-01

    Describes a mass communications program at Texas's San Antonio College that invites Pulitzer Prize recipients to give guest lectures. Includes a list of the speakers who have lectured since the program's inception in 1978, a description of the speakers' accomplishments, and a description of program activities. (MAB)

  9. Kuiper Prize Lecture: Stan Peale's Legacy

    Science.gov (United States)

    Margot, Jean-Luc

    2016-10-01

    Stan Peale's career in planetary science spanned over five decades and yielded an impressive record of high-impact results. His contributions include the prediction of widespread volcanism on Jupiter's moon Io, the derivation of a general theoretical framework that governs the rotational states of bodies subject to tides, the study of the origin and evolution of natural satellites, advances in our understanding of exoplanet dynamics, and the promotion of microlensing searches for exoplanets. Stan also developed an ingenious procedure to determine the size and state of Mercury's core. Because of this work, we know more about the core of Mercury than that of any planet other than Earth. Stan left us an enduring legacy that exemplifies the power of physics to probe the interiors of planets.

  10. Heineman Prize Lecture: Anomaly Cancellation: A Retrospective

    Science.gov (United States)

    Schwarz, John

    2002-04-01

    The mechanism by which gauge and gravitational anomalies cancel in certain string theories is reviewed. A few new tricks are introduced to make the derivation a little simpler, and the string-theoretic interpretation a little clearer, than in the original 1984 work.

  11. Pais Prize Lecture: History and Physics

    Science.gov (United States)

    Heilbron, John

    2006-04-01

    Modern history and experimental physics entered the university together, in the course of the eighteenth century. They shared several practices and projects. Historians began to emphasize physical factors, and so drew on, and occasionally contributed to, meteorology and physical geography; and they developed ancillary disciplines, like numismatics, diplomatics, and paleography, which required the analysis of metals, paper, and inks, and the careful comparison of material objects. In physics, historical reviews of newer subject matters, such as electricity, optics, and pneumatics, guided instruction where neither the facts nor their interpretation compelled consensus. The inherently historical science, geology, was a favorite subject of the age: the earth received a history, and the cosmos, too; evolutionary ideas found applications everywhere. The new physics and the new history became potent weapons of Enlightenment. A product of their collaboration is the lengthiest history of physics ever written, J.G. Fischer's Geschichte der Physik (8 vols., 1801-1808). It appeared within a series edited by Johnn Gottfried Eichhorn, Germany's leading exponent of the ``higher criticism,'' the corrosive application of historical and literary considerations to the stories of the Old Testament. The writings of historians like Eichhorn were more subversive than the work reported by Fischer in so far as humans are more concerned with their place in the world than with the details of its behavior. The coincidental matriculation of modern history and experimental physics, and its consequences, will be discussed.

  12. Allis Prize Lecture: Gaseous Electronics Physics Inside

    Science.gov (United States)

    Garscadden, Alan

    2002-10-01

    I was fortunate to enjoy the advice of K. G. Emeleus during my graduate studies and for many years afterwards. He introduced me to the papers of Will Allis and later I was privileged to correspond with Professor Allis. At this time I had moved from the Queens university environment to work at a large Air Force base. There I have worked with a lot of smart people, including several who also come to the GEC each year to be refreshed and calibrated. A personal overview is presented on a few of the many roles that atomic, molecular and optical physics, including gaseous electronics, play in programs of the Air Force Research Laboratory and subsequently on AF systems and operations. While there have been misses, overall there have been many successes with impacts that provide more effective systems, as recent experiences have demonstrated. Some example studies, involving primarily electron collision physics, successful and unsuccessful in being chosen for application, are discussed.

  13. 2002 Kuiper prize lecture: Dust Astronomy

    Science.gov (United States)

    Grün, Eberhard; Srama, Ralf; Krüger, Harald; Kempf, Sascha; Dikarev, Valeri; Helfert, Stefan; Moragas-Klostermeyer, Georg

    2005-03-01

    Dust particles, like photons, carry information from remote sites in space and time. From knowledge of the dust particles' birthplace and their bulk properties, we can learn about the remote environment out of which the particles were formed. This approach is called "Dust Astronomy" which is carried out by means of a dust telescope on a Dust Observatory in space. Targets for a dust telescope are the local interstellar medium and nearby star forming regions, as well as comets and asteroids. Dust from interstellar and interplanetary sources is distinguished by accurately sensing their trajectories. Trajectory sensors may use the electric charge signals that are induced when charged grains fly through the detector. Modern in-situ dust impact detectors are capable of providing mass, speed, physical and chemical information of dust grains in space. A Dust Observatory mission is feasible with state-of-the-art technology. It will (1) provide the distinction between interstellar dust and interplanetary dust of cometary and asteroidal origin, (2) determine the elemental composition of impacting dust particles, and (3) monitor the fluxes of various dust components as a function of direction and particle masses.

  14. Urey Prize Lecture: Binary Minor Planets

    Science.gov (United States)

    Margot, J. L.

    2004-11-01

    The discovery of binary systems in the near-Earth, main belt, and Kuiper belt populations provides an abundance of new data that expand our knowledge of the physics and chemistry of the solar system. Binary minor planets form as a result of collisional, tidal, and capture processes that are important to study as they play major roles in the formation and evolution of planetary systems. The frequency of occurrence of such processes directly reflects the dynamical environment in the various populations. Observations of binaries provide a powerful way to measure the bulk properties of small bodies, which in turn lead to inferences about their composition and internal structure. These data may offer a rare glimpse of what physical and chemical conditions prevailed when protoplanets formed, and what subsequent evolution took place. In the case of the Kuiper Belt, the study of a handful of binaries forces us to rethink how dense and how bright these bodies are, and to significantly revise our current mass estimates for the entire population. The number of known binary minor planets has increased dramatically over the past few years, with roughly ten new discoveries each year. I will attempt to summarize recent developments, with examples drawn from my observations with the Hubble, Palomar, Keck, Arecibo and Goldstone telescopes.

  15. Urey prize lecture - Water on Mars

    Science.gov (United States)

    Squyres, Steven W.

    1989-01-01

    Taking the heat-transport physics of ice-covered lakes in the Dry Valleys of Antarctica as a model, it is presently suggested that liquid water lakes could have persisted for significant periods under protective ice covers in the Valles Marineris depressions of Mars. Calculations of ground ice thermodynamic stability in a Martian setting indicate that they may exist close to the surface at high latitudes, but are able to persist near the equator only at substantial depths. Such Martian landforms as terrain-softening are attributable to the creep of the Martian regolith under the influence of ground-ice deformation; FEM modeling of the flow process implies terrain-softening to be a near-surface phenomenon.

  16. EPS Prize Lecture. Learning to read words.

    Science.gov (United States)

    Nation, Kate

    2008-08-01

    The ease with which we process the written word belies its complexities and makes it easy to forget that it is a highly skilled behaviour and one that takes time to master. In this paper, I argue that our ability to read words has its roots in our capacity for language. Good progress has been made towards understanding how children discover the systematic relationship between speech sounds and the letters used to represents those sounds, very early in reading development. However, we understand much less about how beginning readers become skilled readers. To understand this, I argue that it is important to view the visual word recognition system within the context of a broader language system, one that incorporates a rich network of semantic and episodic knowledge.

  17. Inducement Prizes and Innovation

    OpenAIRE

    Brunt, Liam; Lerner, Josh; Nicholas, Tom

    2008-01-01

    We examine prizes as an inducement for innovation using a novel dataset of awards for inventiveness offered by the Royal Agricultural Society of England from 1839 to 1939. At annual shows the RASE held competitive trials and awarded medals and monetary prizes (exceeding one million pounds in current prices) to spur technological development. We find large effects of the prizes on contest entries, especially for the Society’s gold medal. Matching award and patent data, we also detect large eff...

  18. The Oskar Klein Memorial Lectures

    CERN Document Server

    1991-01-01

    The Oskar Klein Memorial Lectures, instituted in 1988 and supported by the Royal Swedish Academy of Sciences through its Nobel Committee for Physics, are given at Stockholm University in Sweden, where Oskar Klein was professor in Theoretical Physics 1930-1962.Volume 1 contains the 1988 lectures on "Symmetry and Physics" and "From the Bethe-Hulthén Hypothesis to the Yang-Baxter Equation," given by C N Yang, Nobel Prize winner (1957) and professor at the State University of New York at Stony Brook. The 1989 lectures on "Beyond the Standard Models," referring to models for cosmology and elementar

  19. Tyler Prize nominations sought

    Science.gov (United States)

    Showstack, Randy

    2012-08-01

    Nominations for the 2013 Tyler Prize for Environmental Achievement are being accepted until 21 September. The prize is considered the top international award that honors achievements and contributions in environmental science, protection, energy, and medicine. Among previous recipients are a number of AGU members, including 2012 awardee John Seinfeld, the Louis E. Nohl Professor and professor of chemical engineering at the California Institute of Technology, who was recognized for his contributions to the understanding of the origin, chemistry, and evolution of aerosols in the atmosphere. For more information about the prize, prior honorees, and nomination requirements, see http://www.tylerprize.usc.edu

  20. Lecturing the lecturers

    Science.gov (United States)

    Osborne, Jonathan

    2010-02-01

    João Magueijo's article "Cargo-cult training" about the failings of compulsory educational training for lecturers (December 2009 pp16-17) is an illustration of why some university lecturers do need to be educated about education. His argument that we should use lectures because students like them ignores the large body of educational research stating that this is the least effective form of education. It might, as the well-known aphorism states, be a successful means of transferring the notes of the lecturer to the notes of the students without going through the minds of either, but the evidence shows that only 10% of students learn material in this way. Rather, all the educational literature points to the fact that interactive, discursive methods are much more likely to produce learning with understanding.

  1. Our Own Pulitzer Prizes.

    Science.gov (United States)

    Kalmon, Stephen L.

    1996-01-01

    A school board member in Gilman, Wisconsin, started a literary awards program to improve student writing. Students compete for prizes, and at the end of each year the winning entries are published in a literary magazine. (MLF)

  2. EPA Challenges & Prizes

    Science.gov (United States)

    EPA is a government leader in tapping the power of contributions from the public to help solve difficult problems that affect the environment and public health. Prize competitions allow federal agencies to pay only for successful solutions.

  3. Wolf prize in mathematics

    CERN Document Server

    Hirzebruch, Friedrich; Sinai, Y; Stein, E

    The Wolf Prize, awarded by the Wolf Foundation in Israel, often goes to mathematicians who are in their sixties or older. That is to say, the Prize honours the achievements of a lifetime. T This valuable work features bibliographies, important papers, and speeches (for example at international congresses) of Wolf Prize winners, s uch as R. Bott, A.P. Calderon, A.N. Kolmogorov, M.G. Krein, P. Lax, H. Lewy, L. Lovasz, J. Milnor, J. Moser, I. Piatetski-Shapiro, J.P. Serre, C.L. Siegel, Y. Sinai, E.M. Stein, J. Tits, A. Weil, H. Whitney, A. Wiles and O. Zariski. This is the first time that documents on Wolf Prize winners have been published together. Since the work of the Wolf laureates covers a wide spectrum, much of the mathematics of the 20th century comes to life in this book.

  4. Awarding a Prize

    DEFF Research Database (Denmark)

    Moeran, Brian

    2013-01-01

    This article describes and analyses the selection and prize awarding processes for a biennial ceramics exhibition in Japan. Based on long-term fieldwork in the “art world” (Becker 1982) of contemporary Japanese ceramics, as well as on participant observation of the processes concerned, the article...... addresses and draws upon two sets of sociological writings: one concerned with prizes and awards; the other with evaluative practices....

  5. 2016 Lush Science Prize.

    Science.gov (United States)

    McCann, Jenny; McCann, Terry

    2017-11-01

    The Lush Prize supports animal-free testing by awarding monetary prizes totalling £250,000 to the most effective projects and individuals who have been working toward the goal of replacing animals in product or ingredient safety testing. Prizes are awarded for developments in five strategic areas: Science; Lobbying; Training; Public Awareness; and Young Researchers. In the event of a major breakthrough leading to the replacement of animal tests in the area of 21st Century Toxicology, a Black Box Prize (equivalent to the entire annual fund of £250,000) is awarded. The Science Prize is awarded to the researchers whose work the judging panel believe has made the most significant contribution to the replacement of animal testing in the preceding year. This Background Paper outlines the research projects that were shortlisted and presented to the judging panel as potential candidates for the 2016 Lush Science Prize. This process involved reviewing recent work of the relevant scientific institutions and projects in this area, such as the OECD, CAAT, The Hamner Institutes, ECVAM, UK NC3Rs, and the US Tox21 Programme. Recent developments in toxicity testing research were also identified by searching for relevant published papers in the literature, and analysing abstracts from conferences focusing on animal replacement in toxicity testing that had been held in the preceding 12 months - for example the EUSAAT-Linz, Society of Toxicology, and SEURAT-1 conferences. 2017 FRAME.

  6. Eight lectures on theoretical physics

    CERN Document Server

    Planck, Max

    1997-01-01

    In 1909 the great German physicist and Nobel Prize winner Max Planck (1858-1947) delivered a series of eight lectures at Columbia University giving a fascinating overview of the new state of physics, which he had played a crucial role in bringing about. The first, third, fifth, and sixth lectures present his account of the revolutionary developments occasioned when he first applied the quantum hypothesis to blackbody radiation. The reader is given an invaluable opportunity to witness Planck's thought processes both on the level of philosophical principles as well as their application to physi

  7. Nobel Prize winning physicist to speak at Rensselaer Nov. 20 Leon Lederman to discuss pre college science education

    CERN Document Server

    2002-01-01

    Leon Lederman, Nobel Prize-winner, will offer some radical ideas for improving pre-college science education when he delivers the annual Robert Resnick Lecture at Rensselaer Polytechnic Institute's Russell Sage Laboratory (1/2 page).

  8. Wolf prize in physics

    CERN Document Server

    Piran, Tsvi

    2016-01-01

    The Wolf Foundation began its activities in 1976, with an initial endowment donated by the Wolf family. Within a very short period of time after its initiation, the Wolf prize has become one of the major signs for recognition of scientific achievements and excellence. This volume is devoted to a selection of Wolf Prize laureates in Physics and each has included two respective major publications as well as a commentary written by the laureate describing his scientific career. Readers around the world are provided a unique opportunity to get a glimpse of how scientific processes work in physics, and to comprehend how these laureates have left an indelible imprint on scientific history.

  9. Universal scaling in sports ranking

    Science.gov (United States)

    Deng, Weibing; Li, Wei; Cai, Xu; Bulou, Alain; Wang, Qiuping A.

    2012-09-01

    Ranking is a ubiquitous phenomenon in human society. On the web pages of Forbes, one may find all kinds of rankings, such as the world's most powerful people, the world's richest people, the highest-earning tennis players, and so on and so forth. Herewith, we study a specific kind—sports ranking systems in which players' scores and/or prize money are accrued based on their performances in different matches. By investigating 40 data samples which span 12 different sports, we find that the distributions of scores and/or prize money follow universal power laws, with exponents nearly identical for most sports. In order to understand the origin of this universal scaling we focus on the tennis ranking systems. By checking the data we find that, for any pair of players, the probability that the higher-ranked player tops the lower-ranked opponent is proportional to the rank difference between the pair. Such a dependence can be well fitted to a sigmoidal function. By using this feature, we propose a simple toy model which can simulate the competition of players in different matches. The simulations yield results consistent with the empirical findings. Extensive simulation studies indicate that the model is quite robust with respect to the modifications of some parameters.

  10. Universal scaling in sports ranking

    CERN Document Server

    Deng, Weibing; Cai, Xu; Bulou, Alain; Wang, Qiuping A

    2011-01-01

    Ranking is a ubiquitous phenomenon in the human society. By clicking the web pages of Forbes, you may find all kinds of rankings, such as world's most powerful people, world's richest people, top-paid tennis stars, and so on and so forth. Herewith, we study a specific kind, sports ranking systems in which players' scores and prize money are calculated based on their performances in attending various tournaments. A typical example is tennis. It is found that the distributions of both scores and prize money follow universal power laws, with exponents nearly identical for most sports fields. In order to understand the origin of this universal scaling we focus on the tennis ranking systems. By checking the data we find that, for any pair of players, the probability that the higher-ranked player will top the lower-ranked opponent is proportional to the rank difference between the pair. Such a dependence can be well fitted to a sigmoidal function. By using this feature, we propose a simple toy model which can simul...

  11. Citations Prize 2011 Citations Prize 2011

    Science.gov (United States)

    Webb, Steve; Harris, Simon

    2011-12-01

    Physics in Medicine & Biology (PMB) awards its 'Citations Prize' to the authors of the original research paper that has received the most citations in the preceding five years (according to the Institute for Scientific Information (ISI)). The lead author of the winning paper is presented with the Rotblat Medal (named in honour of Professor Sir Joseph Rotblat who was the second—and longest serving—Editor of PMB, from 1961-1972). The winning co-authors each receive a certificate. Susan Hagness (left) receiving the Rotblat Medal from Robert Jeraj of PMB's Editorial Board (right) on behalf of Mariya Lazebnik. The winner of the 2011 Citations Prize for the paper which has received the most citations in the previous 5 years (2006-2010) is A large-scale study of the ultrawideband microwave dielectric properties of normal, benign and malignant breast tissues obtained from cancer surgeries Authors: Mariya Lazebnik, Dijana Popovic, Leah McCartney, Cynthia B Watkins, Mary J Lindstrom, Josephine Harter, Sarah Sewall, Travis Ogilvie, Anthony Magliocco, Tara M Breslin, Walley Temple, Daphne Mew, John H Booske, Michal Okoniewski and Susan C Hagness Reference: Mariya Lazebnik et al 2007 Phys. Med. Biol. 52 6093-115 Discussion of the significance of the winning paper can be found on medicalphysicsweb (medicalphysicsweb.org/cws/article/research/47814). Our congratulations go to the winning authors. Steve Webb Editor-in-Chief Simon Harris Publisher

  12. Nobel Prize ceremony 2013

    CERN Document Server

    2013-01-01

    On 10 December 2013 particle physics took central stage at the Nobel ceremony in Stockholm. Among the invitees were Fabiola Gianotti, former ATLAS spokesperson, Joseph Incandela, CMS Spokesperson, and CERN theorist Luis Alvarez-Gaume. They share their feelings of the memorable day with us.   Overview of the 2013 Nobel Prize Award Ceremony at the Stockholm Concert Hall. © Nobel Media AB 2013. Photo: Alex Ljungdahl. Fabiola Gianotti and Joe Incandela, at the Nobel Banquet in the Stockholm City Hall.   "It was an honour and a thrill for us to attend such a memorable Nobel prize ceremony and we are very grateful to Peter Higgs for having included us among his invited guests. The ceremony held some special moments for the LHC. In his speech prior to the award of the Nobel prize to Francois Englert and Peter Higgs by King Carl XVI Gustaf of Sweden, Lars Brink (Chair of the Physics Nobel Prize Committee) stressed the importance of the results from the LHC exper...

  13. The 2010 Broad Prize

    Science.gov (United States)

    Education Digest: Essential Readings Condensed for Quick Review, 2011

    2011-01-01

    A new data analysis, based on data collected as part of The Broad Prize process, provides insights into which large urban school districts in the United States are doing the best job of educating traditionally disadvantaged groups: African-American, Hispanics, and low-income students. Since 2002, The Eli and Edythe Broad Foundation has awarded The…

  14. The Abel Prize

    CERN Document Server

    Holden, Helge

    2010-01-01

    Presents the winners of the first five Abel Prizes in mathematics: 2003 - Jean-Pierre Serre; 2004 - Sir Michael Atiyah and Isadore Singer; 2005 - Peter D Lax; 2006 - Lennart Carleson; and 2007 - S R Srinivasa Varadhan. This book provides an autobiography or an interview, a curriculum vitae, and a complete bibliography of each laureate

  15. 1997 Nobel Prizes

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 2; Issue 11. 1997 Nobel Prizes. Information and Announcements Volume 2 Issue 11 November 1997 pp 111-111. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/002/11/0111-0111. Resonance – Journal of ...

  16. Nobel Prize in Chemistry

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 9; Issue 4. Nobel Prize in Chemistry – 2003 The Gateway for Perfect Health. S M Srideshikan S K Srivatsa. General Article Volume 9 Issue 4 April 2004 pp 61-70. Fulltext. Click here to view fulltext PDF. Permanent link:

  17. Century of Nobel Prizes

    Indian Academy of Sciences (India)

    1859-02-19

    GENERAL I ARTICLE. Century of Nobel Prizes. 1903 Chemistry Award: Svante August Arrhenius (1859-1927). Shridhar R Gadre. Svante August Arrhenius was born at Wijk, near lake Malar, in. Sweden on February 19, 1859. His parents were Svante Gustav. Arrhenius (a town land surveyor) and Carolina Christina.

  18. EPS Young Physicist Prize - CORRECTION

    CERN Multimedia

    2009-01-01

    The original text for the article 'Prizes aplenty in Krakow' in Bulletin 30-31 assigned the award of the EPS HEPP Young Physicist Prize to Maurizio Pierini. In fact he shared the prize with Niki Saoulidou of Fermilab, who was rewarded for her contribution to neutrino physics, as the article now correctly indicates. We apologise for not having named Niki Saoulidou in the original article.

  19. IEEE Prize for Lucio Rossi

    CERN Multimedia

    IEEE Council on Superconductivity

    2007-01-01

    Lucio Rossi receives his prize from John Spargo, Chairman of the IEEE Council on Superconductivity (left), and Martin Nisenoff, Chairman of the Council on Superconductivity's Awards Committee (right).

  20. Nobel prizes: contributions to cardiology.

    Science.gov (United States)

    Mesquita, Evandro Tinoco; Marchese, Luana de Decco; Dias, Danielle Warol; Barbeito, Andressa Brasil; Gomes, Jonathan Costa; Muradas, Maria Clara Soares; Lanzieri, Pedro Gemal; Gismondi, Ronaldo Altenburg

    2015-08-01

    The Nobel Prize was created by Alfred Nobel. The first prize was awarded in 1901 and Emil Adolf von Behring was the first laureate in medicine due to his research in diphtheria serum. Regarding cardiology, Nobel Prize's history permits a global comprehension of progress in pathophysiology, diagnosis and therapeutics of various cardiac diseases in last 120 years. The objective of this study was to review the major scientific discoveries contemplated by Nobel Prizes that contributed to cardiology. In addition, we also hypothesized why Carlos Chagas, one of our most important scientists, did not win the prize in two occasions. We carried out a non-systematic review of Nobel Prize winners, selecting the main studies relevant to heart diseaseamong the laureates. In the period between 1901 and 2013, 204 researches and 104 prizes were awarded in Nobel Prize, of which 16 (15%) studies were important for cardiovascular area. There were 33 (16%) laureates, and two (6%) were women. Fourteen (42%) were American, 15 (45%) Europeans and four (13%) were from other countries. There was only one winner born in Brazil, Peter Medawar, whose career was all in England. Reviewing the history of the Nobel Prize in physiology or medicine area made possible to identify which researchers and studies had contributed to advances in the diagnosis, prevention and treatment of cardiovascular diseases. Most winners were North Americans and Europeans, and male.

  1. Autophagy Captures the Nobel Prize

    National Research Council Canada - National Science Library

    Tooze, Sharon A; Dikic, Ivan

    2016-01-01

    This year's Nobel Prize in Physiology or Medicine has been awarded to Yoshinori Ohsumi for the discovery of the molecular principles governing autophagy, an intracellular degradation pathway routed...

  2. Nobel Prizes: Contributions to Cardiology

    Directory of Open Access Journals (Sweden)

    Evandro Tinoco Mesquita

    2015-08-01

    Full Text Available The Nobel Prize was created by Alfred Nobel. The first prize was awarded in 1901 and Emil Adolf von Behring was the first laureate in medicine due to his research in diphtheria serum. Regarding cardiology, Nobel Prize’s history permits a global comprehension of progress in pathophysiology, diagnosis and therapeutics of various cardiac diseases in last 120 years. The objective of this study was to review the major scientific discoveries contemplated by Nobel Prizes that contributed to cardiology. In addition, we also hypothesized why Carlos Chagas, one of our most important scientists, did not win the prize in two occasions. We carried out a non-systematic review of Nobel Prize winners, selecting the main studies relevant to heart diseaseamong the laureates. In the period between 1901 and 2013, 204 researches and 104 prizes were awarded in Nobel Prize, of which 16 (15% studies were important for cardiovascular area. There were 33 (16% laureates, and two (6% were women. Fourteen (42% were American, 15 (45% Europeans and four (13% were from other countries. There was only one winner born in Brazil, Peter Medawar, whose career was all in England. Reviewing the history of the Nobel Prize in physiology or medicine area made possible to identify which researchers and studies had contributed to advances in the diagnosis, prevention and treatment of cardiovascular diseases. Most winners were North Americans and Europeans, and male.

  3. Nobel Prizes: Contributions to Cardiology

    Directory of Open Access Journals (Sweden)

    Evandro Tinoco Mesquita

    2015-01-01

    Full Text Available The Nobel Prize was created by Alfred Nobel. The first prize was awarded in 1901 and Emil Adolf von Behring was the first laureate in medicine due to his research in diphtheria serum. Regarding cardiology, Nobel Prize’s history permits a global comprehension of progress in pathophysiology, diagnosis and therapeutics of various cardiac diseases in last 120 years. The objective of this study was to review the major scientific discoveries contemplated by Nobel Prizes that contributed to cardiology. In addition, we also hypothesized why Carlos Chagas, one of our most important scientists, did not win the prize in two occasions. We carried out a non-systematic review of Nobel Prize winners, selecting the main studies relevant to heart diseaseamong the laureates. In the period between 1901 and 2013, 204 researches and 104 prizes were awarded in Nobel Prize, of which 16 (15% studies were important for cardiovascular area. There were 33 (16% laureates, and two (6% were women. Fourteen (42% were American, 15 (45% Europeans and four (13% were from other countries. There was only one winner born in Brazil, Peter Medawar, whose career was all in England. Reviewing the history of the Nobel Prize in physiology or medicine area made possible to identify which researchers and studies had contributed to advances in the diagnosis, prevention and treatment of cardiovascular diseases. Most winners were North Americans and Europeans, and male.

  4. Nobel Prizes: Contributions to Cardiology

    Energy Technology Data Exchange (ETDEWEB)

    Mesquita, Evandro Tinoco; Marchese, Luana de Decco; Dias, Danielle Warol; Barbeito, Andressa Brasil; Gomes, Jonathan Costa; Muradas, Maria Clara Soares; Lanzieri, Pedro Gemal; Gismondi, Ronaldo Altenburg, E-mail: ronaldo@floralia.com.br [Universidade Federal Fluminense, Niterói, RJ (Brazil)

    2015-08-15

    The Nobel Prize was created by Alfred Nobel. The first prize was awarded in 1901 and Emil Adolf von Behring was the first laureate in medicine due to his research in diphtheria serum. Regarding cardiology, Nobel Prize’s history permits a global comprehension of progress in pathophysiology, diagnosis and therapeutics of various cardiac diseases in last 120 years. The objective of this study was to review the major scientific discoveries contemplated by Nobel Prizes that contributed to cardiology. In addition, we also hypothesized why Carlos Chagas, one of our most important scientists, did not win the prize in two occasions. We carried out a non-systematic review of Nobel Prize winners, selecting the main studies relevant to heart diseaseamong the laureates. In the period between 1901 and 2013, 204 researches and 104 prizes were awarded in Nobel Prize, of which 16 (15%) studies were important for cardiovascular area. There were 33 (16%) laureates, and two (6%) were women. Fourteen (42%) were American, 15 (45%) Europeans and four (13%) were from other countries. There was only one winner born in Brazil, Peter Medawar, whose career was all in England. Reviewing the history of the Nobel Prize in physiology or medicine area made possible to identify which researchers and studies had contributed to advances in the diagnosis, prevention and treatment of cardiovascular diseases. Most winners were North Americans and Europeans, and male.

  5. Nobel Prize in Physics 20161

    Indian Academy of Sciences (India)

    The article describes the theorietical work in the field of con- densed matter physics for which the 2016 Nobel Prize in Physics was awarded. Introduction. The 2016 Nobel Prize in Physics was awarded for theoretical dis- coveries of topological phase transitions and topological phases of matter. It honours people whose ...

  6. Tensor Rank

    OpenAIRE

    Erdtman, Elias; Jönsson, Carl

    2012-01-01

    This master's thesis addresses numerical methods of computing the typical ranks of tensors over the real numbers and explores some properties of tensors over finite fields. We present three numerical methods to compute typical tensor rank. Two of these have already been published and can be used to calculate the lowest typical ranks of tensors and an approximate percentage of how many tensors have the lowest typical ranks (for some tensor formats), respectively. The third method was developed...

  7. Nobel Lecture: Topological quantum matter*

    Science.gov (United States)

    Haldane, F. Duncan M.

    2017-10-01

    Nobel Lecture, presented December 8, 2016, Aula Magna, Stockholm University. I will describe the history and background of three discoveries cited in this Nobel Prize: The "TKNN" topological formula for the integer quantum Hall effect found by David Thouless and collaborators, the Chern insulator or quantum anomalous Hall effect, and its role in the later discovery of time-reversal-invariant topological insulators, and the unexpected topological spin-liquid state of the spin-1 quantum antiferromagnetic chain, which provided an initial example of topological quantum matter. I will summarize how these early beginnings have led to the exciting, and currently extremely active, field of "topological matter."

  8. Evolution of National Nobel Prize Shares in the 20th Century

    CERN Document Server

    Schmidhuber, Juergen

    2010-01-01

    We analyze the evolution of cumulative national shares of Nobel Prizes since 1901, properly taking into account that most prizes were divided among several laureates. We rank by citizenship at the moment of the award, and by country of birth. Surprisingly, graphs of this type have not been published before, even though they powerfully illustrate the century's migration patterns (brain drains and gains) in the sciences and other fields.

  9. Rank Dynamics

    Science.gov (United States)

    Gershenson, Carlos

    Studies of rank distributions have been popular for decades, especially since the work of Zipf. For example, if we rank words of a given language by use frequency (most used word in English is 'the', rank 1; second most common word is 'of', rank 2), the distribution can be approximated roughly with a power law. The same applies for cities (most populated city in a country ranks first), earthquakes, metabolism, the Internet, and dozens of other phenomena. We recently proposed ``rank diversity'' to measure how ranks change in time, using the Google Books Ngram dataset. Studying six languages between 1800 and 2009, we found that the rank diversity curves of languages are universal, adjusted with a sigmoid on log-normal scale. We are studying several other datasets (sports, economies, social systems, urban systems, earthquakes, artificial life). Rank diversity seems to be universal, independently of the shape of the rank distribution. I will present our work in progress towards a general description of the features of rank change in time, along with simple models which reproduce it

  10. T-regulatory cells-Triumph of perseverance: The Crafoord Prize for Polyarthritis in 2017.

    Science.gov (United States)

    Wollheim, Frank A

    2018-02-01

    The Crafoord Prize in Polyarthritis ranks as one of the most prestigious prizes and can be awarded only if the Royal Swedish Academy of Sciences decides the likelihood of prize worthy progress in the field, and at most every 4th year. This has happened only four times since 1982. This year the 5th Laureates were Shimon Sakaguchi, Fred Ramsdell, and Alexander Rudensky with the motivation "for their discoveries relating to regulatory T cells, which counteract harmful immune reactions in arthritis and other autoimmune diseases". Here I review the history of their contributions and its impact in rheumatology. Copyright © 2018. Published by Elsevier Inc.

  11. ACADEMIC TRAINING LECTURES-QUESTIONNAIRE

    CERN Multimedia

    Françoise Benz

    2004-01-01

    ACADEMIC TRAINING Françoise Benz tel. 73127 academic.training@cern.ch SUGGEST AND WIN! Its time to plan the 2004-2005 lecture series. From today until March 19 you have the chance to give your contribution to planning for next year's Academic Training Lecture Series. At the web site: http://cern.ch/Academic.Training/questionnaire you will find questionnaires proposing topics in high energy physics, applied physics and science and society. Answering the questionnaire will help ensure that the selected topics are as close as possible to your interests. In particular requests and comments from students will be much appreciated. To encourage your contribution, the AT Committee will reward one lucky winner with a small prize, a 50 CHF coupon for a book purchase at the CERN bookshop.

  12. Einstein, Nobel Prize, and Accelerators

    CERN Document Server

    Jarlskog, C

    2005-01-01

    We are celebrating the year of physics thanks to Einstein’s monumental contributions a hundred years ago. Indeed, the current field of accelerator physics is also deeply indebted to him. Why did it take more than a decade and a half for him to be "crowned" in Stockholm by the Nobel Prize? Did he get the Prize for the "wrong" thing? Based on original material from the archives of the Swedish Academy of Sciences, I will discuss how Einstein got the Nobel Prize and will give a short summary of his everlasting impact on the field of accelerator physics.

  13. Europlanet Prize for Public Engagement

    Science.gov (United States)

    Fouchet, Thierry

    2016-10-01

    The Europlanet Prize for Public Engagement with Planetary Science is awarded annually. Through the Prize, Europlanet aims to recognise achievements in engaging European citizens with planetary science and to raise the profile of outreach within the scientific community. It is awarded to individuals or groups who have developed innovative practices in planetary science communication and whose efforts have significantly contributed to a wider public engagement with planetary science.

  14. Haagen-Smit Prize 2016

    Science.gov (United States)

    Singh, Hanwant

    2017-03-01

    The Executive Editors and the Publisher of Atmospheric Environment take great pleasure in announcing the 2016 "Haagen-Smit Prize", designed to recognize outstanding papers published in Atmospheric Environment. The Prize is named in honor of Prof. Arie Jan Haagen-Smit, a pioneer in the field of air pollution and one of the first editors of the International Journal of Air Pollution, a predecessor to Atmospheric Environment.

  15. Urey Prize Lecture - Planetary evolution and the origin of life

    Science.gov (United States)

    Mckay, Christopher P.

    1991-01-01

    One of the principal questions concerning planetary evolution and life's origins relates to the early-earth organic material's origination in situ, outer solar system importation, or simple irrelevance to the emergence of organisms. Additional considerations encompass the character of interstellar organic material and its relationship to outer solar system organic compounds, and the possibility of life's emergence in the early Mars. Attention is given to the essentiality of liquid water for life-forms, in the role not only of a reaction medium among molecules but that of a basis for hydrophylic and hydrophobic groups' bonding.

  16. The RSC Faraday prize lecture of 1989 on platinum.

    Science.gov (United States)

    Thomas, John Meurig

    2017-08-25

    In 1861, Michael Faraday gave one of his last Friday Evening Discourses at the Royal Institution of Great Britain, London, on platinum, which he described as "this beautiful, magnificent and valuable metal". More than a hundred and twenty years later (in 1989), the author re-enacted, at the Royal Institution, many of the demonstrations that Faraday carried out in his memorable Discourse. This article outlines many of Faraday's views on, and experiments with, platinum. It also describes the continuing importance and utilization of platinum, both as perceived in 1989 and from present perspectives.

  17. 1999 KUIPER PRIZE LECTURE. Cometary Origin of the Biosphere

    Science.gov (United States)

    Delsemme, Armand H.

    2000-08-01

    Most of the biosphere was brought on the primitive Earth by an intense bombardment of comets. This included the atmosphere, the seawater and those volatile carbon compounds needed for the emergence of life. Comets were thrown into the inner Solar System by the strong perturbation induced by the growth of the giant planets' cores. The bulk of the Earth's bombardment came from those comets that accreted in Jupiter's zone, where the original deuterium enrichment had been diminished by steam coming from the hot, inner parts of the Solar System. This steam had condensed into icy chunks before their accretion into larger cometary nuclei. In contrast, comets that accreted in the zones of the outer giant planets kept their interstellar isotopic enrichments. Those comets contributed to the Earth's bombardment for a small amount only; they were mostly ejected into the Oort cloud and are the major source of the long-period comets observed today. The short-period comets, which come from the Kuiper Belt, should also have the same interstellar enrichment. The deuterium enrichment of seawater, accurately predicted by the previous scenario, has become one of the best telltales for the cometary origin of our biosphere. This cometary origin may have far-reaching cosmological consequences, in particular for the origin of life in other planetary systems.

  18. Lars Onsager Prize Lecture: Statistical Dynamics of Disordered Systems

    Science.gov (United States)

    Fisher, Daniel S.

    2013-03-01

    The properties of many systems are strongly affected by quenched disorder that arose from their past history but is frozen on the time scales of interest. Although equilibrium phases and phase transitions in disordered materials can be very different from their counterparts in pure systems, the most striking phenomena involve non-equilibrium dynamics. The state of understanding of some of these will be reviewed including approach to equilibrium in spin glasses and the onset of motion in driven systems such as vortices in superconductors or earthquakes on geological faults. The potential for developing understanding of short-term evolutionary dynamics of microbial populations by taking advantage of the randomness of their past histories and the biological complexities will be discussed briefly.

  19. Fluid Dynamics Prize Otto Laporte Lecture:Turbulence and Aeroacoustics

    Science.gov (United States)

    Comte-Bellot, Genevieve

    2014-11-01

    Some significant advances obtained over the years for two closely related fields, Turbulence and Aeroacoustics, are presented. Particular focus is placed on experimental results and on physical mechanisms. For example, for a 2D channel flow, skewness factors of velocity fluctuations are discussed. The study of isotropic turbulence generated by grids in the «Velvet wind tunnel» of Stanley Corrsin, constitutes a masterpiece. Of particular note are the Eulerian memory times, analysed for all wavenumbers. Concerning hot-wire anemometry, the potential of the new constant voltage technique is presented. Some results obtained with Particule Image Velocimetry are also reported. Two flow control examples are illustrated: lift generation for a circular cylinder, and noise reduction for a high speed jet. Finally, the propagation of acoustic waves through turbulence is considered. Experimental data are here completed by numerical simulations showing the possible occurrence of caustics.

  20. Urey prize lecture: On the diversity of plausible planetary systems

    Science.gov (United States)

    Lissauer, J. J.

    1995-01-01

    Models of planet formation and of the orbital stability of planetary systems are used to predict the variety of planetary and satellite systems that may be present within our galaxy. A new approximate global criterion for orbital stability of planetary systems based on an extension of the local resonance overlap criterion is proposed. This criterion implies that at least some of Uranus' small inner moons are significantly less massive than predicted by estimates based on Voyager volumes and densities assumed to equal that of Miranda. Simple calculations (neglecting planetary gravity) suggest that giant planets which acrete substantial amounts of gas while their envelopes are extremely distended ultimately rotate rapidly in the prgrade direction.

  1. Andreas Acrivos Dissertation Prize Lecture: Phytoplankton in Flow

    Science.gov (United States)

    Durham, William M.

    2012-11-01

    Phytoplankton are small, unicellular organisms that form the base of the marine food web and are cumulatively responsible for half the global oxygen production. While phytoplankton live in an environment characterized by ubiquitous fluid flow, the impact of hydrodynamic conditions on their ecology remain poorly understood. In this talk, I report on two novel biophysical mechanisms based on the interaction between phytoplankton motility and fluid shear. First, I will consider ``thin phytoplankton layers,'' important hotspots of ecological activity that are found meters beneath the ocean surface and contain cell concentrations up to two orders of magnitude above ambient. Using a combination of experiments, individual-based simulations, and continuum modeling, we have shown that layers can form when the vertical migration of phytoplankton is disrupted by hydrodynamic shear. This mechanism which we call ``gyrotactic trapping'' is capable of triggering thin phytoplankton layers under hydrodynamic conditions typical of the environments that often harbor thin layers. Second, I will discuss the potential for turbulent shear to produce patchiness in the spatial distribution of motile phytoplankton. Field measurements have revealed that motile phytoplankton form aggregations at the Kolmogorov scale, whereas non-motile cells do not. We propose a new mechanism for the formation of this small-scale patchiness based on the interplay of gyrotactic motility and turbulent shear. Using laboratory experiments, an analytical model of vortical flow, and isotropic turbulence generated via Direct Numerical Simulations, we found that motile phytoplankton rapidly aggregate, whereas non-motile cells remain randomly distributed. Taken together, these two mechanisms demonstrate that the interaction of cell motility with flow plays a fundamental role in phytoplankton ecology and, as a consequence, can contribute to shape macroscale characteristics of the ocean.

  2. Oliver E. Buckley Condensed Matter Prize Lecture: Topological Insulators

    Science.gov (United States)

    Kane, Charles

    2012-02-01

    A topological insulator is a material that is an insulator on its interior, but has special conducting states on its surface. These surface states are unlike any other known two dimensional conductor. They are characterized by a unique Dirac type dispersion relation and are protected by a topological property of the material's underlying electronic band structure. In this talk we will outline our path to the theoretical discovery of this phase and describe the physical properties of the two dimensional topological insulator - also known as a quantum spin Hall insulator - as well as its three dimensional generalization. We will then go on to discuss more recent developments, including the topological classification of point and line defects in topological insulators and superconductors. The latter may provide a venue for observing Majorana fermion states and for realizing proposals for topological quantum computation.

  3. Wellcome Prize Lecture. Cell surface, ion-sensing receptors.

    Science.gov (United States)

    Riccardi, Daniela

    2002-07-01

    Changes in extracellular calcium (Ca(2+)o) concentration ([Ca2+]o) affect kidney function both under basal and hormone-stimulated conditions. The molecular identification of an extracellular Ca(2+)-sensing receptor (CaR) has confirmed a direct role of Ca(2+)o on parathyroid and kidney function (i.e. independent of calciotropic hormones) as a modulator of Ca2+ homeostasis. In addition, evidence accumulated over the last 10 years has shown that CaR is also expressed in regions outside the calcium homeostatic system where its role is largely undefined but seems to be linked to regulation of local ionic homeostasis. The parathyroid and kidney CaRs are 1081 and 1079 amino acids long, respectively, and belong to the type III family of G protein-coupled receptors (GPCRs), which includes other CaRs, metabotropic glutamate receptors and putative vomeronasal organ receptors. For the CaR, its low (millimolar) affinity for Ca2+, its positive cooperativity and its large ion-sensing extracellular domain, indicate that the receptor is more sensitive to changes in net cationic charge rather than to a specific ligand. Mg2+, trivalent cations of the lanthanide series and polyvalent cations such as spermine and aminoglycoside antibiotics can all activate the receptor in vitro with EC50 values in the micromolar range for trivalent and polyvalent cations or in the millimolar range for Ca2+ and Mg2+. In addition to true CaR agonists, CaR sensitivity to Ca(2+)o is also susceptible to allosteric modulation by ionic strength, L-amino acids and by pharmacological agents. This review will address endogenous and exogenous CaR agonists, the role of the receptor in the calcium homeostatic system and some speculation on possible role(s) of the CaR in regions not involved in mineral ion homeostasis.

  4. Pierce Prize Lecture: High Velocity Clouds: Cosmological and Galactic Weather

    Science.gov (United States)

    Sembach, K.

    2001-12-01

    The Milky Way and its surrounding environs contain gas moving at high velocities with respect to the Sun. For the past half century, most of the information available for these high velocity clouds (HVCs) has come from H I 21cm surveys. Improvements in these surveys have recently led to the idea that some of the high velocity H I clouds may be located outside the Milky Way within the Local Group. Such a hypothesis is testable by various means, but the neutral gas content of the clouds tells only half of a much more complex story. In this talk I will present new information about the ionized gas within HVCs, their impact on the gaseous atmosphere of the Galaxy, and their relevance to the cosmic web of hot gas that may contain a significant fraction of the baryonic material in the low-redshift universe.

  5. Szilard Prize Lecture: Seismic Monitoring of Nuclear Explosions

    Science.gov (United States)

    Richards, Paul

    2006-04-01

    Seismic monitoring of the more than 2000 nuclear test explosions since 1945 has been vigorously pursued, both to track the weapons development of potential adversaries, and to support initiatives in nuclear arms control, including various test ban treaties. Major funding from the US Department of Defense built up new global seismographic networks and over several decades established practical capability in monitoring nuclear explosions ``teleseismically'' (i.e. from distances more than about 1500 km), for tests that the testing nation did not attempt to conceal. What then is the capability to monitor compliance with, for example, the Comprehensive Nuclear-Test-Ban Treaty (CTBT) of 1996, particularly if evasion scenarios are considered? Note that the CTBT, though not ratified by some countries (including the US), is now being monitored by networks that include seismographic stations at ``regional'' distances (< 1500 km) from candidate explosion locations. Years of R and D have shown that regional signals can be used to monitor down to yields significantly lower than can be detected and identified teleseismically. A US National Academy of Sciences study in 2002 concluded that ``an underground nuclear explosion cannot be confidently hidden if its yield is larger than 1 or 2 kt.'' About 1000 earthquakes and chemical explosions are now detected per day, and documented via seismic data, providing plenty of challenges for nuclear explosion monitoring organizations. Explosion monitoring capability will improve in many parts of the world, due to the growth of networks that monitor even small earthquakes to study seismic hazard. But political problems can impede improved international explosion monitoring, due to national restrictions on data access.

  6. The Path of Carbon in Photosynthesis [Nobel Prize Lecture

    Science.gov (United States)

    Calvin, Melvin

    1961-12-11

    It is almost sixty years since Emil Fischer was describing on a platform such as this one some of the work which led to the basic knowledge of the structure of glucose and its relatives. Today we will be concerned with a description of the experiments which have led to a knowledge of the principal reactions by which those carbohydrate structures are created by photosynthetic organisms from carbon dioxide and water, using the energy of light. The speculations on the way in which carbohydrate was built from carbon dioxide began not long after the recognition of the basic reaction and were carried forward first by Justus von Liebig and then by Adolf von Baeyer and, finally, by Richard Wilstatter and Arthur Stoll into this century. Actually, the route by which animal organisms performed the reverse reaction, that is, the combustion of carbohydrate to carbon dioxide and water with the utilization of the energy resulting from this combination, turned out to be the first one to be successfully mapped, primarily by Otto Meyerhoi and Hans Krebs. Our own interest in the basic process of solar energy conversion by green plants began some time in the years between 1935 and 1937, during my postdoctoral studies with Professor Michael Polanyi at Manchester. It was there I first became conscious of the remarkable properties of coordinated metal compounds, particularly metalloporphyins as represented by heme and chlorophyll. A study was begun at that time, which is still continuing, on the electronic behavior of such metalloporphyrins. It was extended and generalized by the stimulus of Professor Gilbert N. Lewis upon my arrival in Berkeley. I hope these continuing studies may one day contribute to the understanding of the precise way in which chlorophyll and its relatives accomplish the primary quantum conversion into chemical potential which is used to drive the carbohydrate synthesis reaction.

  7. Bok Prize Lecture (shared) The Brown Dwarf Radial Velocity Survey

    Science.gov (United States)

    Charbonneau, Dave

    2004-03-01

    The swarm of nearby brown dwarfs and very low mass stars is an attractive sample for radial velocity monitoring. Such work is best conducted with an echelle spectrograph operating at infrared wavelengths where these objects(i) are most luminous, (ii) have a forest of molecular features, providing an excellent velocity metric, and {iii) are superimposed on the telluric spectrum, which yields the requisite wavelength calibration. I will present first results from such a survey, with a precision sufficient to detect Jupiter-mass planets with orbital periods of less than a year. Should such systems be uncovered, the planets would be amenable to direct study, due to system proximity, and the favorable contrast ratio between the planet and parent object.

  8. Lars Onsager Prize Lecture: A Random Walk Through Theoretical Physics

    Science.gov (United States)

    Affleck, Ian

    2012-02-01

    A historical account will be given of my efforts to apply conformal field theory techniques to experimentally relevant models of condensed matter. This began with a so far unsuccessful attempt to find the exact critical exponents for the localization transition in the integer quantum Hall effect, using techniques developed by field/string theorists. It was followed by a program to classify critical behavior of Heisenberg antiferromagnetic spin chains of arbitrary spin magnitude. It eventually led to a general theory of the low energy behavior of quantum impurity models including exact solutions for non-Fermi liquid critical points.

  9. Warner Prize Lecture: A New View on Planetary Orbital Dynamics

    Science.gov (United States)

    Ford, Eric B.

    2013-01-01

    Prior to the discovery of exoplanets, astronomers fine tuned theories of planet formation to explain detailed properties of the solar system. Doppler planet searches revealed that many giant planets orbit close to their host star or in highly eccentric orbits. These and subsequent observations inspired new theories of planet formation that invoke strong mutual gravitation interactions in multiple planet systems to explain the excitation of orbital eccentricities and even short-period giant planets. NASA's Kepler mission has identified over 300 systems with multiple transiting planet candidates, including many potentially rocky planets. Most of these systems include multiple planets with sizes between Earth and Neptune and closely-spaced orbits. These systems represent another new and unexpected class of planetary systems and provide an opportunity to test the theories developed to explain the properties of giant exoplanets. I will describe how transit timing observations by Kepler are characterizing the gravitational effects of mutual planetary perturbations for hundreds of planets and providing precise (but complex) constraints on planetary masses, densities and orbits, even for planetary systems with faint host stars. I will discuss early efforts to translate these observations into new constraints on the formation and orbital evolution of planetary systems with low-mass planets.

  10. Rossi Prize Lecture: Gamma Ray Bursts: Origins and Consequences

    Science.gov (United States)

    Meszaros, P.

    2000-12-01

    Some of the major stepping stones towards uncovering the mystery of gamma ray bursts will be discussed. This is an unfinished process, new observations being expected in the near future. I will review the current observational status, and discuss the present theoretical understanding of GRB, as well as the possible impact of future missions and experiments.

  11. Sakurai Prize Lecture: Thirty Years of Precision Electroweak Physics

    Science.gov (United States)

    Sirlin, Alberto

    2002-04-01

    We discuss the development of the theory of electroweak radiative corrections and its role in testing the Standard Model, predicting the top quark mass, constraining the Higgs boson mass, and searching for deviations that may signal the presence of new physics.

  12. Panofsky Prize Lecture: Evidence for Oscillation of Atmospheric Neutrinos

    Science.gov (United States)

    Totsuka, Yoji

    2002-04-01

    Atmospheric neutrinos are decay products of pions and kaons (and of their decay products muons) produced by nuclear interactions of cosmic rays with air nuclei. Though their flux is not known well, only within 20 %, physics quantities that are independent of the flux uncertainty exist. The ratio of the number of muon neutrinos to the number of electron neutrinos is estimated to be accurate within 5 %. The other quantity is the shape of the zenith-angle distribution. Kamiokande and Super-Kamiokande are water Cherenkov detectors with 3,000 ton and 50,000 ton pure water, respectively. Kamiokande was operational in 1983 - 1996, and Super-K in 1996 - 2001 and 2003 - in future. We had already noted in 1988 that the observed μ/e ratio, which represented ν_mu/ν_e, was smaller by about 40 %. Later in 1994 we noted that the zenith angle distribution of muon neutrinos was strongly distorted, namely much fewer muons observed in the upward direction, while downward-going muons were what we expected. Electrons were quite normal. In 1996 Super-Kamiokande was ready. Its fiducial volume is 22.5 kton, much larger than Kamiokande's 1.04 kton. In 1998 based on 25.5 kton years of data we presented convincing results on the small μ/e ratio which was caused by fewer number of muons in the upward direction. The essential feature of the observed anomaly was that the disappearance of muon neutrinos depended strongly on their path length and on their energies. Electrons showed no anomaly within the experimental limit. These results were quantitatively and almost uniquely explained by oscillation of muon neutrinos to tau neutrinos, thus evidence for the finite but tiny mass of neutrinos.

  13. How corticosteroids control inflammation: Quintiles Prize Lecture 2005.

    Science.gov (United States)

    Barnes, Peter J

    2006-06-01

    Corticosteroids are the most effective anti-inflammatory therapy for many chronic inflammatory diseases, such as asthma but are relatively ineffective in other diseases such as chronic obstructive pulmonary disease (COPD). Chronic inflammation is characterised by the increased expression of multiple inflammatory genes that are regulated by proinflammatory transcription factors, such as nuclear factor-kappaB and activator protein-1, that bind to and activate coactivator molecules, which then acetylate core histones to switch on gene transcription. Corticosteroids suppress the multiple inflammatory genes that are activated in chronic inflammatory diseases, such as asthma, mainly by reversing histone acetylation of activated inflammatory genes through binding of liganded glucocorticoid receptors (GR) to coactivators and recruitment of histone deacetylase-2 (HDAC2) to the activated transcription complex. At higher concentrations of corticosteroids GR homodimers also interact with DNA recognition sites to active transcription of anti-inflammatory genes and to inhibit transcription of several genes linked to corticosteroid side effects. In patients with COPD and severe asthma and in asthmatic patients who smoke HDAC2 is markedly reduced in activity and expression as a result of oxidative/nitrative stress so that inflammation becomes resistant to the anti-inflammatory actions of corticosteroids. Theophylline, by activating HDAC, may reverse this corticosteroid resistance. This research may lead to the development of novel anti-inflammatory approaches to manage severe inflammatory diseases.

  14. Kupier prize lecture: Sources of solar-system carbon

    Science.gov (United States)

    Anders, Edward; Zinner, Ernst

    1994-01-01

    We have tried to deconvolve Solar-System carbon into its sources, on the basis of C-12/C-13 ratios (equivalent to R). Interstellar SiC in meteorites, representing greater than 4.6-Ga-old stardust from carbon stars, is isotopically heavier (bar R = 38 +/- 2) than Solar-System carbon (89), implying that the latter contains an additional, light component. A likely source are massive stars, mainly Type II supernovae and Wolf-Rayet stars, which, being O-rich, eject their C largely as CO rather than carbonaceous dust. The fraction of such light C in the Solar System depends on R(sub light) in the source. For R(sub light) = 180-1025 (as in 'Group 4' meteoritic graphite spherules, which apparently came from massive stars greater than 4.6 Ga ago), the fraction of light C is 0.79-0.61. Similar results are obtained for present-day data on red giants and interstellar gas. Although both have become enriched in C-13 due to galactic evolution (to bar-R = 20 and 57), the fraction of the light component in interstellar gas again is near 0.7. (Here bar R represents the mean of a mixture calculated via atom fractions; it is not identical to the arithmetic mean R). Interstellar graphite, unlike SiC, shows a large peak at R approximately equal 90, near the solar value. Although some of the grains may be of local origin, others show anomalies in other elements and hence are exotic. Microdiamonds, with R = 93, also are exotic on the basis of their Xe and N. Apparently R approximately 90 was a fairly common composition 4.6 Ga ago, of stars as well as the ISM.

  15. Hans A. Bethe Prize Lecture: The Primordial Helium Abundance

    Science.gov (United States)

    Peimbert, Manuel

    2012-03-01

    It is generally accepted that the production of the light elements (He, D, and Li) during the early stages of the expansion of the Universe is one of the three pillars of the Big Bang theory. The main results obtained from the observational determination of the primordial helium abundance, Yp, and its comparison with the value predicted by Big Bang Nucleosynthesis will be presented, in particular: a) the recognition that galaxies form with Yp in the 0.24 to 0.26 range, b) that Yp was produced during the Big Bang, c) that Yp is fundamental as a critical test for cosmological theories and the baryonic content of the Universe, and d) that the value of Yp provides an observational constraint on the number of light neutrino species, which is smaller than four and probably equal to three. In addition, the present status of the observationally determined Yp value based on extragalactic H II regions will be discussed.

  16. Fluid Dynamics Prize Lecture: The Micromechanics of Colloidal Dispersions

    Science.gov (United States)

    Brady, John F.

    2012-11-01

    What do corn starch, swimming spermatozoa, DNA and self-assembling nanoparticles have in common? They are all (or can be modeled as) ``particles'' dispersed in a continuum suspending fluid where hydrodynamic interactions compete with thermal (Brownian) and interparticle forces to set structure and determine properties. These systems are ``soft'' as compared to molecular systems largely because their number density is much less and their time scales much longer than atomic or molecular systems. In this talk I will describe the common framework for modeling these diverse systems and the essential features that any hydrodynamic modeling must incorporate in order to capture the correct behavior. Actually computing the hydrodynamics in an accurate and efficient manner is the real challenge, and I will illustrate past successes and current efforts with examples drawn from the diffusion and rheology of colloids to the ``swimming'' of catalytic nanomotors.

  17. 2001 Tom W. Bonner Prize in Nuclear Physics Lecture

    Science.gov (United States)

    Geller, Richard

    2001-04-01

    As long as the Highly Charged Ions (HCI) were obtained with a hot cathode ion source and foil strippers the reliability of the accelerators remained poor. Therefore in 1973, I thought of an ion source based an Electron Cyclotron Resonance (ECR) plasmas trapped inside magnetic mirrors since such devices deliver stable confinement plasmas with energetic electrons and cold ions which are the main ingredients for HCI production. In addition ECR eliminates the use of hot cathodes and this improves considerably their reliability. In 1974 we transformed a voluminous and obsolete " min B fusion mirror device " into an ECR Ion Source (ECRIS) delivering excellent HCI beams. However due to its large size it used too much electrical power (3 MW). To be practical we had to launch a smaller ECRIS with permanent magnets and such an ECRIS worked in 1979 at Grenoble. Between 1980-90 we developed half a dozen of increasingly performing prototypes and many accelerator groups followed the trend. This world wide success is a clear recognition of its reliability and its ability to yield intense HCI beams. However for these very reasons one rarely speaks about ECRIS ; in addition the ECRIS is far away from the targets so it is invisible and moreover it is unsubstantial since it is just an empty cavity filled with 3 invisible components : a) rarefied gas b) microwaves c) specific magnetic field lines… These components must be tuned to create a central ECR zone (where the Larmor frequency equals the microwave frequency) to ignite the plasma inside its magnetic mirror trap ; then one has to adjust accurately the parameters a) b) c) in order to prevent the on-set of always possible plasma instabilities. A well tuned ECRIS is ready to yield intense HCI beams without interruption for weeks and months, in continuous or pulsed regimes. At present an ECRIS has become a " must " for : (i) Nuclear reactions with very small cross-sections - where one has no other solution than to increase the incident ion dose (ex : superheavies - rare isotopes, etc.). (ii) Long duration runs with extreme heavy ion energy on existing machines (ex. CERN : 33 TeV Pb ions, for gluon quark plasma). (iii) Cancer therapy with heavy ions where the physicians require extremely reproducible doses for therapy protocols. The future of ECRIS will depend on further applications : for instance the production of very short life (1+) isotope ions delivered by ISOL systems in continuous regime. For this we developed in 1995 the so called (1+/N+) ECRIS charge booster which catches the (1+) ions before they are adsorpted on the walls. Moreover for pulsed accelerators we developed in 1998 an ECRIT (ECR Ion Trap) charge booster which is simultaneously a (1+) ions accumulator and HCI beam buncher.

  18. EAS Tycho Brahe prize lecture 2011. Hipparcos: a retrospective

    Science.gov (United States)

    Perryman, Michael

    2011-10-01

    The Hipparcos satellite was launched in 1989. It was the first, and remains to date the only, attempt at performing large-scale astrometric measurements from space. Hipparcos marked a fundamentally new approach to the field of astrometry, revolutionising our knowledge of the positions, distances, and space motions of the stars in the solar neighbourhood. In this retrospective, I look back at the processes which led to the mission's acceptance, provide a short summary of the underlying measurement principles and the experiment's scientific achievements, and a conclude with a brief summary of its principal legacy—the Gaia mission.

  19. Urey Prize Lecture - Chaotic dynamics in the solar system

    Science.gov (United States)

    Wisdom, Jack

    1987-01-01

    Attention is given to solar system cases in which chaotic solutions of Newton's equations are important, as in chaotic rotation and orbital evolution. Hyperion is noted to be tumbling chaotically; chaotic orbital evolution is suggested to be of fundamental importance to an accounting for the Kirkwood gaps in asteroid distribution and for the phase space boundary of the chaotic zone at the 3/1 mean-motion commensurability with Jupiter. In addition, chaotic trajectories in the 2/1 chaotic zone reach very high eccentricities by a route that carries them to high inclinations temporarily.

  20. Aneesur Rahman Prize for Computational Physics Lecture: Addressing Dirac's Challenge

    Science.gov (United States)

    Chelikowsky, James

    2013-03-01

    After the invention of quantum mechanics, P. A. M. Dirac made the following observation: ``The underlying physical laws necessary for the mathematical theory of a large part of physics and the whole of chemistry are thus completely known, and the difficulty is only that the exact application of these laws leads to equations much too complicated to be soluble. It therefore becomes desirable that approximate practical methods of applying quantum mechanics should be developed, which can lead to an explanation of the main features of complex atomic systems...'' The creation of ``approximate practical methods'' in response to Dirac's challenge has included the one electron picture, density functional theory and the pseudopotential concept. The combination of such methods in conjunction with contemporary computational platforms and new algorithms offer the possibility of predicting properties of materials solely from knowledge of the atomic species present. I will give an overview of progress in this field with an emphasis on materials at the nanoscale. Support from the Department of Energy and the National Science Foundation is acknowledged.

  1. Online lectures.

    Science.gov (United States)

    Wink, Diane M

    2010-01-01

    In this bimonthly series, the author examines how nurse educators can use Internet and Web-based computer technologies such as search, communication, and collaborative writing tools; social networking and social bookmarking sites; virtual worlds; and Web-based teaching and learning programs. This article describes the creation of lectures that can be embedded in Web-based courses and presentations.

  2. Interview with Abel Prize Recipient Lennart Carleson

    DEFF Research Database (Denmark)

    Raussen, Martin; Skau, Christian

    2008-01-01

    Lennart Carleson was the recipient of the 2006 Abel Prize. On May 22, 2006, prior to the Abel Prize celebration in Oslo, Carleson was interviewed. The interview was later shown on Norwegian television.......Lennart Carleson was the recipient of the 2006 Abel Prize. On May 22, 2006, prior to the Abel Prize celebration in Oslo, Carleson was interviewed. The interview was later shown on Norwegian television....

  3. Safety Day Prize Competition: results and answers

    CERN Multimedia

    HSE Unit

    2014-01-01

    The three winners of the Safety Day Prize Competition are...   • 1st Prize: Fernando LEITE PEREIRA – smoke detector • 2nd Prize: Thomas DE BORTOLI – water filter jug • 3rd Prize: Matti KALLIOKOSKI – safety goggles Please see the image below for the answers to the questionnaire. If you have any questions regarding the Safety Day, please contact: safety.communication@cern.ch. And again, thank you to all the participants!

  4. ARWU vs. Alternative ARWU Ranking: What are the Consequences for Lower Ranked Universities?

    Directory of Open Access Journals (Sweden)

    Milica Maričić

    2017-05-01

    Full Text Available The ARWU ranking has been a source of academic debate since its development in 2003, but the same does not account for the Alternative ARWU ranking. Namely, the Alternative ARWU ranking attempts to reduce the influence of the prestigious indicators Alumni and Award which are based on the number of received Nobel Prizes and Fields Medals by alumni or university staff. However, the consequences of the reduction of the two indicators have not been scrutinized in detail. Therefore, we propose a statistical approach to the comparison of the two rankings and an in-depth analysis of the Alternative ARWU groups. The obtained results, which are based on the official data, can provide new insights into the nature of the Alternative ARWU ranking. The presented approach might initiate further research on the Alternative ARWU ranking and on the impact of university ranking’s list length. JEL Classification: C10, C38, I23

  5. Nobel prize awards in radiochemistry

    Energy Technology Data Exchange (ETDEWEB)

    Adloff, J.P. [Strasbourg Univ. (France)

    2012-07-01

    In 1996 the Editors of Radiochimica Acta brought out a special volume of the journal to celebrate the hundredth anniversary of the discovery of radioactivity. On the occasion of the 50{sup th} anniversary of Radiochimica Acta, which follows closely upon the centenary of Marie Curie's second Nobel Prize in 1911, the author has the privilege to informally review 'Radiochemistry and Nobel Prize Awards', including discoveries of radioelements and new fields in chemistry based on radiochemical methods. (orig.)

  6. Keeping an Eye on the Prize

    Energy Technology Data Exchange (ETDEWEB)

    Hazi, A U

    2007-02-06

    Setting performance goals is part of the business plan for almost every company. The same is true in the world of supercomputers. Ten years ago, the Department of Energy (DOE) launched the Accelerated Strategic Computing Initiative (ASCI) to help ensure the safety and reliability of the nation's nuclear weapons stockpile without nuclear testing. ASCI, which is now called the Advanced Simulation and Computing (ASC) Program and is managed by DOE's National Nuclear Security Administration (NNSA), set an initial 10-year goal to obtain computers that could process up to 100 trillion floating-point operations per second (teraflops). Many computer experts thought the goal was overly ambitious, but the program's results have proved them wrong. Last November, a Livermore-IBM team received the 2005 Gordon Bell Prize for achieving more than 100 teraflops while modeling the pressure-induced solidification of molten metal. The prestigious prize, which is named for a founding father of supercomputing, is awarded each year at the Supercomputing Conference to innovators who advance high-performance computing. Recipients for the 2005 prize included six Livermore scientists--physicists Fred Streitz, James Glosli, and Mehul Patel and computer scientists Bor Chan, Robert Yates, and Bronis de Supinski--as well as IBM researchers James Sexton and John Gunnels. This team produced the first atomic-scale model of metal solidification from the liquid phase with results that were independent of system size. The record-setting calculation used Livermore's domain decomposition molecular-dynamics (ddcMD) code running on BlueGene/L, a supercomputer developed by IBM in partnership with the ASC Program. BlueGene/L reached 280.6 teraflops on the Linpack benchmark, the industry standard used to measure computing speed. As a result, it ranks first on the list of Top500 Supercomputer Sites released in November 2005. To evaluate the performance of nuclear weapons systems, scientists

  7. Nobel Prize for Physics-2003

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 9; Issue 2. Nobel Prize for Physics–2003 - Matter Close to Absolute Zero. R Srinivasan Andal Narayanan. General Article Volume 9 Issue 2 February 2004 pp 50-63. Fulltext. Click here to view fulltext PDF. Permanent link:

  8. Madhu Sudan Receives Nevanlinna Prize

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 7; Issue 12. Madhu Sudan Receives Nevanlinna Prize. Meena Mahajan Priti Shankar. Research News Volume 7 Issue 12 December 2002 pp 84-90. Fulltext. Click here to view fulltext PDF. Permanent link:

  9. Nobel Prize in Physics-1997

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 3; Issue 2. Nobel Prize in Physics – 1997 Laser Cooling and Trapping. Vasant Natarajan R Srinivasan. General Article Volume 3 Issue 2 February 1998 pp 16-27. Fulltext. Click here to view fulltext PDF. Permanent link:

  10. Collide@CERN - public lecture

    CERN Multimedia

    2012-01-01

    CERN, the Republic and Canton of Geneva and the City of Geneva are delighted to invite you to a public lecture by Gilles Jobin, first winner of the Collide@CERN Geneva Dance and Performance Artist-in-residence Prize, and his CERN inspiration partner, Joao Pequenao. They will present their work in dance and science at the Globe of Science and Innovation on Wednesday, 23 May 2012 at 7 p.m. (doors open at 6.30 p.m.).   
                                                  Programme 19:00 Opening address by - Professor Rolf-Dieter Heuer, CERN Director-General, - Ariane Koek...

  11. Nobel prizes that changed medicine

    CERN Document Server

    2012-01-01

    This book brings together in one volume fifteen Nobel Prize-winning discoveries that have had the greatest impact upon medical science and the practice of medicine during the 20th century and up to the present time. Its overall aim is to enlighten, entertain and stimulate. This is especially so for those who are involved in or contemplating a career in medical research. Anyone interested in the particulars of a specific award or Laureate can obtain detailed information on the topic by accessing the Nobel Foundation's website. In contrast, this book aims to provide a less formal and more personal view of the science and scientists involved, by having prominent academics write a chapter each about a Nobel Prize-winning discovery in their own areas of interest and expertise.

  12. IEEE Prize for Lucio Rossi

    CERN Multimedia

    2007-01-01

    Lucio Rossi receives his prize from John Spargo, Chairman of the IEEE Council on Superconductivity (left), and Martin Nisenoff, Chairman of the Council on Superconductivity’s Awards Committee (right). (Photo: IEEE Council on Superconductivity)With the magnets installed in the tunnel and work on the interconnections almost completed, Lucio Rossi has reaped the rewards of fifteen years of work. And yet, when the physicist from Milan arrived to take charge of the group responsible for the superconducting magnets in 2001, success seemed far from assured. Endowed with surprising levels of energy, Lucio Rossi, together with his team, ensured that production of these highly complex magnets got underway. Today, that achievement earns them the recognition not only of CERN but also of the international superconducting community. It is for this achievement that Lucio Rossi was awarded the prize by the IEEE’s (Institute of Electrical an...

  13. Landau's Nobel Prize in Physics

    CERN Document Server

    Larsson, Mats

    2016-01-01

    Work of Lev Landau had a profound impact on the physics in 20th century. Landau had created the paradigms that had framed the conversations on the outstanding problems in physics for decades. He has laid the foundations for our understanding of quantum matter such as superfluidity, superconductivity and the theory of Fermi Liquid. Here we present sampled Nobel Archive data on the winning nomination that led to the Nobel Prize in Physics in 1962.

  14. Autophagy Captures the Nobel Prize.

    Science.gov (United States)

    Tooze, Sharon A; Dikic, Ivan

    2016-12-01

    This year's Nobel Prize in Physiology or Medicine has been awarded to Yoshinori Ohsumi for the discovery of the molecular principles governing autophagy, an intracellular degradation pathway routed via lysosomes or vacuoles. It is a story of a simple yet insightful yeast genetic screen that revealed the inner circuitry of one of the most powerful quality-control pathways in cells. Copyright © 2016 Elsevier Inc. All rights reserved.

  15. Patents, Inducement Prizes, and Contestant Strategy

    DEFF Research Database (Denmark)

    Davis, Jerome; Davis, Lee N.

    2006-01-01

    Debate over the merits of patents versus inducement prizes has tended to ignore the signaling roles of patents, and totally ignores the impact of patent signaling on prize contests. This paper asks: How does patent signaling affect the strategic choices of firms considering entering prize contests......? First, we consider contests that do not allow patenting, then contests that do. If patenting is not allowed, we argue, patent-holders, both internal and external to the contest, can adversely impact prize contests by claiming prize winner violation of their patents, and suing for damages. The likelihood...... of such challenges being made can deter entry, particularly in contests requiring large sunk costs. Furthermore, the firm's decisionmaking process will discriminate against entering prize contests and favor R&D projects with patentable outcomes. Together, these problems may circumscribe any future wider role...

  16. Special issue: Culham Thesis Prize winners

    Science.gov (United States)

    Ham, C. J.

    2015-01-01

    The Culham Thesis Prize is awarded annually to the nominee who has displayed an excellence in the execution of the scientific method as witnessed by the award of Doctor of Philosophy in Plasma Science from a UK or Irish university. The thesis content should exhibit significant new work and originality, clearly driven by the nominee, be well explained and demonstrate a good understanding of the subject. The prize is awarded at the Institute of Physics Plasma Physics Group Spring Conference and the prize winner gives an invited talk about their thesis work. The prize is sponsored by Culham Centre for Fusion Energy.

  17. Academic Training: Academic Training Lectures-Questionnaire

    CERN Multimedia

    2004-01-01

    ACADEMIC TRAINING Françoise Benz tel. 73127 academic.training@cern.ch SUGGEST AND WIN! Its time to plan the 2004-2005 lecture series. From today until March 19 you have the chance to give your contribution to planning for next year's Academic Training Lecture Series. At the web site: http://cern.ch/Academic.Training/questionnaire you will find questionnaires proposing topics in high energy physics, applied physics and science and society. Answering the questionnaire will help ensure that the selected topics are as close as possible to your interests. In particular requests and comments from students will be much appreciated. To encourage your contribution, the AT Committee will reward one lucky winner with a small prize, a 50 CHF coupon for a book purchase at the CERN bookshop.

  18. Interview with Abel Prize recipient Lennart Carleson

    DEFF Research Database (Denmark)

    Raussen, Martin; Skau, Christian

    2006-01-01

    The interview was conducted in Oslo on May 22nd 2006 prior to the Abel prize celebration and was later shown on Norwegian TV.......The interview was conducted in Oslo on May 22nd 2006 prior to the Abel prize celebration and was later shown on Norwegian TV....

  19. Interview with Abel Prize recipient Lennart Carleson

    DEFF Research Database (Denmark)

    Raussen, Martin; Skau, Christian

    2006-01-01

    The interview was conducted in Oslo on May 22nd 2006  prior to the Abel prize celebration and was later shown on Norwegian TV.......The interview was conducted in Oslo on May 22nd 2006  prior to the Abel prize celebration and was later shown on Norwegian TV....

  20. Interview with Abel Prize recipient Lennart Carleson

    DEFF Research Database (Denmark)

    Raussen, Martin; Skau, Christian

    2006-01-01

    The interview was conducted in Oslo on May22nd 2006 prior to the Abel prize celebration and was later shown on Norwegian TV.......The interview was conducted in Oslo on May22nd 2006 prior to the Abel prize celebration and was later shown on Norwegian TV....

  1. Interview with Abel Prize Recipient Lennart Carleson

    DEFF Research Database (Denmark)

    Raussen, Martin; Skau, Christian

    2007-01-01

    Lennart Carleson is the recipient of the 2006 Abel Prize of the Norwegian Academy of Science and Letters. On May 22, 2006, prior to the Abel Prize celebration i Oslo, Carleson was interviewed by Martin Raussen of Aalborg University and Christian Skau of the Norwegian University of Science...

  2. Broad Prize: Do the Successes Spread?

    Science.gov (United States)

    Samuels, Christina A.

    2011-01-01

    When the Broad Prize for Urban Education was created in 2002, billionaire philanthropist Eli Broad said he hoped the awards, in addition to rewarding high-performing school districts, would foster healthy competition; boost the prestige of urban education, long viewed as dysfunctional; and showcase best practices. Over the 10 years the prize has…

  3. Synthesis and the Nobel Prize in Chemistry

    Science.gov (United States)

    Seeman, Jeffrey I.

    2017-10-01

    The question often arises as to who may have deserved a Nobel Prize but was not awarded one. Rarely is this discussion extended to who should have received more than one Nobel Prize, but in the field of organic synthesis there are some compelling candidates.

  4. Ginzburg deserved Nobel prize 50 years back

    CERN Multimedia

    Golovchansky, V

    2003-01-01

    "Vitali Ginzburg deserved a Nobel prize fifty years back, Leonid Keldysh, academician of the Russian Academy of Sciences, who was Ginzburg's disciple, told Tass. "The Ginzburg-Landau phenomenal theory of superconductivity deserved a Nobel prize right upon being produced. It was a work of intransient importance" (1/2 page).

  5. Innovation Inducement Prizes: Connecting Research to Policy

    Science.gov (United States)

    Besharov, Douglas J.; Williams, Heidi

    2012-01-01

    Innovation inducement prizes have been used for centuries. In the United States, a recent federal policy change--the America COMPETES Reauthorization Act of 2010--clarified and simplified a path by which all federal agencies can offer innovation inducement prizes, thus intensifying interest in how government agencies can most effectively design…

  6. The 2009 Nobel Prize in Physics

    Indian Academy of Sciences (India)

    get these prizes. 1. Introduction. The winners of the 2009 Nobel prize in physics, shown in. Figure 1, have been recognized for two achievements in optics that have revolutionized modern life in the past few decades. The first is the ..... In Figure 4(b), we show an image of malaria- infected red blood cells trapped by a laser ...

  7. MIT professor wins major international math prize

    CERN Multimedia

    Allen, S

    2004-01-01

    Mathematicians Isadore Singer of MIT and Sir Michael Francis Atiyah of the University of Edinburgh will share an $875,000 award as winners of the second Abel Prize, which some hope will come to be seen as a Nobel Prize for math.

  8. 2014 WSEAT X-Prize

    Energy Technology Data Exchange (ETDEWEB)

    Bosiljevac, Thomas [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Kramer, Sharlotte [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Laing, John [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2014-10-01

    The 2014 WSEAT X-Prize is modeled as a double blind study to challenge the computational and material mechanics communities methodologies to develop better capabilities in modeling and experimentation to predict the failure in ductile metals. The challenge is presented as a distinct, yet relatively, simple geometry with all reported modeling predictions blind to each of the modeling teams. The experimental testing is validated by two independent test labs to confirm the experimentally observed behavior and results are unbiased and repeatable. The WSEAT X-Prize was issued to both external participants and internal participants as the Sandia Fracture Challenge 2 (SFC2) on May 30, 2014. A Challenge Supplemental Information Packet was sent to participants on August 13, 2014 to Prior years SFCs focused on the ability to predict failures under a quasi-static loading condition that focused on either a shear or tensile-dominated failure mode. This year’s challenge focuses on a geometry with a shear and/or tensile-dominated failure mode influenced by a moderate strain-rate ductile fracture in a metallic alloy.

  9. Fullerene discoverers win nobel prize

    Energy Technology Data Exchange (ETDEWEB)

    Rotman, D.

    1996-10-16

    Two Rice University (Houston) chemists, Robert F. Curl and Richard E. Smalley, and a scientist at the University of Sussex (Brighton, U.K.), Harold W. Kroto, have won the 1996 Nobel Prize in Chemistry for the joint discovery of buckminsterfullerenes - soccer ball-shaped carbon molecules. The novel form of carbon, which was initially synthesized by the scientists in 1985 as C{sub 60} and C{sub 70} has led to the development of {open_quotes}an entirely new branch of chemistry... with consequences in such diverse areas as astrochemistry, superconductivity, and material chemistry/physics,{close_quotes} according to the Swedish Academy of Sciences (Stockholm). For chemists, the structure is {open_quotes}uniquely beautiful and satisfying,{close_quotes} the academy says.

  10. Science Underlying 2008 Nobel Prizes

    Science.gov (United States)

    Caldwell, Bernadette A.

    2009-01-01

    JCE offers a wealth of materials for teaching and learning chemistry that you can explore online. In the list below, Bernadette Caldwell of the Editorial Staff suggests additional resources that are available through JCE for teaching the science behind some of the 2008 Nobel Prizes . Discovering and Applying the Chemistry of GFP The Royal Swedish Academy of Sciences awarded the 2008 Nobel Prize in Chemistry for the discovery and development of the green fluorescent protein, GFP to three scientists: Osamu Shimomura, Martin Chalfie, and Roger Y. Tsien. These scientists led the field in discovering and introducing a fluorescing protein from jellyfish into cells and genes under study, which allows researchers to witness biochemistry in action. Now tags are available that emit light in different colors, revealing myriad biological processes and their interactions simultaneously. Identifying HPV and HIV, HIV's Replication Cycle, and HIV Virus-Host Interactions The Nobel Assembly at Karolinska Institutet awarded the 2008 Nobel Prize in Medicine or Physiology for their discovery of human immunodeficiency virus (HIV) to two scientists: Françoise Barré-Sinoussi and Luc Montagnier; and for his discovery of human papilloma viruses [HPV] causing cervical cancer to one scientist, Harald zur Hausen. Diseases caused by these infectious agents significantly affect global health. While isolating and studying the virus, researchers discovered HIV is an uncommon retrovirus that infects humans and relies on the host to make its viral DNA, infecting and killing the host's white blood cells, ultimately destroying the immune systems of infected humans. Related Resources at JCE Online The Journal has published articles relating to GFP specifically, and more generally to fluorescing compounds applied to biochemistry. The Journal has also published an article and a video on protease inhibition—a strategy to suppress HIV's biological processes. With the video clips, an accompanying guide

  11. A Kiss Lajos-díj 2016. évi nyertese: dr. Póczos Rita [Winner of the 2016 Lajos Kiss Prize: Dr Rita Póczos

    Directory of Open Access Journals (Sweden)

    Hoffmann, István

    2016-12-01

    Full Text Available The Lajos Kiss Prize, awarded every two or three years since 2006, is considered to be a highly prestigious award for young onomasticians. The 2016 winner of the prize is Dr Rita Póczos, senior lecturer at the Department of Hungarian Linguistics of the University of Debrecen. She was given this award for her contribution to Hungarian Historical Onomastics, especially for her research on place names.

  12. A Kiss Lajos-díj 2014. évi nyertese: dr. Slíz Mariann [The 2014 winner of Lajos Kiss Prize: Dr Mariann Slíz

    Directory of Open Access Journals (Sweden)

    Hoffmann, István

    2014-12-01

    Full Text Available The Lajos Kiss Prize, awarded every two or three years since 2006, is considered to be a highly prestigious award for young onomasticians. The 2014 winner of the prize is Dr Mariann Slíz, senior lecturer at the Department of Hungarian Linguistics and Finno-Ugric Studies of Eötvös Loránd University, Budapest. She earned this award for her contribution to Hungarian Onomastics, especially in research on personal names.

  13. Industry Lecture 2010

    DEFF Research Database (Denmark)

    Kragh, Helge

    2010-01-01

    Sammendrag af "Industry Lecture", Norsk Kjemisk Selskap, Universitetet i Oslo, givet 15/10 2010.......Sammendrag af "Industry Lecture", Norsk Kjemisk Selskap, Universitetet i Oslo, givet 15/10 2010....

  14. A Nobel Prize in Czechoslovakia; Yaroslav Geyrovskiy

    National Research Council Canada - National Science Library

    Brabernets, Irzhi

    1960-01-01

    The notification of the awarding of a Nobel Prize to Yaroslav Geyrovskiy in the field of chemistry in l959 came to the scientist while he was at work at the Polarographic Institute of the Czechoslovak...

  15. Nobel Prize for work on broken symmetries

    CERN Multimedia

    2008-01-01

    The 2008 Nobel Prize for Physics goes to three physicists who have worked on broken symmetries in particle physics. The announcement of the 2008 Nobel Prize for physics was transmitted to the Globe of Science and Innovation via webcast on the occasion of the preview of the Nobel Accelerator exhibition.On 7 October it was announced that the Royal Swedish Academy of Sciences had awarded the 2008 Nobel Prize for physics to three particle physicists for their fundamental work on the mechanisms of broken symmetries. Half the prize was awarded to Yoichiro Nambu of Fermilab for "the discovery of the mechanism of spontaneous broken symmetry in subatomic physics". The other half is shared by Makato Kobayashi of Japan’s KEK Institute and Toshihide Maskawa of the Yukawa Institute at the University of Kyoto "for the discovery of the origin of the broken symmetry which predicts the existence of at least three families of quarks in Nature". At th...

  16. 2017 ISCB Overton Prize: Christoph Bock.

    Science.gov (United States)

    Fogg, Christiana N; Kovats, Diane E; Berger, Bonnie

    2017-01-01

    The International Society for Computational Biology (ISCB) each year recognizes the achievements of an early to mid-career scientist with the Overton Prize. This prize honors the untimely death of Dr. G. Christian Overton, an admired computational biologist and founding ISCB Board member. Winners of the Overton Prize are independent investigators who are in the early to middle phases of their careers and are selected because of their significant contributions to computational biology through research, teaching, and service. ISCB is pleased to recognize Dr. Christoph Bock, Principal Investigator at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences in Vienna, Austria, as the 2017 winner of the Overton Prize. Bock will be presenting a keynote presentation at the 2017 International Conference on Intelligent Systems for Molecular Biology/European Conference on Computational Biology (ISMB/ECCB) in Prague, Czech Republic being held during July 21-25, 2017.

  17. ACFA and IPAC announce accelerator prizes

    CERN Multimedia

    CERN Bulletin

    2010-01-01

    Steve Myers, CERN's Director for Accelerators and Technology. The Asian Committee for Future Accelerators (ACFA) has joined forces with the first International Particle Accelerator Conference, IPAC’10, to award prizes for outstanding work in the field of accelerators. The conference replaces the regional conferences of the Americas, Europe and Asia and will be hosted by the three regions on a rotational basis (see CERN Courier). The ACFA/IPAC’10 Prizes Selection Committee, chaired by Won Namkung of Pohang Accelerator Laboratory, decided on the prizes and the names of the winners at a meeting on 20 January. The awards will be made during IPAC’10, which will be held in Kyoto on 23-28 May. Jie Wei. (Courtesy Tsinghua University.) Steve Myers, Director for Accelerators and Technology at CERN, receives an Achievement Prize for Outstanding Work in the Accelerator Field with no Age Limit “for his numerous outstanding contributions to the design, construction, commissio...

  18. "Special 2005 EPS HEPP prize colloquium"

    CERN Multimedia

    Maximilien Brice

    2005-01-01

    Colloquium celebrating the awarding of the 2005 EPS High Energy Particle Physics prize to Heinrich Wahl and the NA31 collaboration which showed for the first time Direct CP Violation in the decay of neutral K mesons.

  19. Strong-force theorists scoop Noble Prize

    CERN Multimedia

    Durrani, Matin

    2004-01-01

    Three US theorists have shared the 2004 Nobel Prize in Physics "for the discovery of asymptotic freedom in the theory of the strong interaction". Their theoretical work explains why quarks behave almost as free particles at high energies (½ page)

  20. Ranking library materials

    OpenAIRE

    Lewandowski, Dirk

    2015-01-01

    Purpose: This paper discusses ranking factors suitable for library materials and shows that ranking in general is a complex process and that ranking for library materials requires a variety of techniques. Design/methodology/approach: The relevant literature is reviewed to provide a systematic overview of suitable ranking factors. The discussion is based on an overview of ranking factors used in Web search engines. Findings: While there are a wide variety of ranking factors appl...

  1. ACADEMIC TRAINING LECTURES-QUESTIONNAIRE: SUGGEST AND WIN!

    CERN Multimedia

    Françoise Benz

    2002-01-01

    Its time to plan for the 2002-2003 lecture series. From today until April 26 you have the chance to give your contribution to improved planning for next year's Academic Training Lectures Series. At the web site, you will find questionnaires concerning the following different categories: high energy physics, applied physics, science and society and post-graduate student lectures. Answering the questionnaire will help ensure that the selected topics are as close as possible to your interests. In particular requests and comments from students will be much appreciated. To encourage your contribution, the AT Committee is offering 10 prizes of a self-teach web based training course to people who provide their email address when filling in the questionnaire. The 10 winners will be chosen randomly from the replies received before the closing date.

  2. Interview with Abel Prize recipient Srinivasa Varadhan

    DEFF Research Database (Denmark)

    Raussen, Martin; Skau, Christian

    2007-01-01

    His Majesty King Harald presented the Abel Prize for 2007 to Srinivasa Varadhan at an award ceremony in the University Aula in Oslo on the 22nd May, 2007. The interview was conducted the day before the ceremony.......His Majesty King Harald presented the Abel Prize for 2007 to Srinivasa Varadhan at an award ceremony in the University Aula in Oslo on the 22nd May, 2007. The interview was conducted the day before the ceremony....

  3. Interview with Abel Prize Recipient Srinivasa Varadhan

    DEFF Research Database (Denmark)

    Raussen, Martin; Skau, Christian

    2008-01-01

    His Majesty King Harald presented the Abel Prize for 2007 to Srinivasa Varadhan at an award ceremony in the University Aula in Oslo on the 22nd May, 2007. The interview was conducted the day before the ceremony.......His Majesty King Harald presented the Abel Prize for 2007 to Srinivasa Varadhan at an award ceremony in the University Aula in Oslo on the 22nd May, 2007. The interview was conducted the day before the ceremony....

  4. College portraits, surgeons and the Archibald Prize.

    Science.gov (United States)

    Royle, John Peterson

    2005-06-01

    The Royal Australasian College of Surgeons is fortunate to have a wonderful collection of portraits, which date from William Cheselden's portrait in the mid 18th century to the latest of immediate past president, Kingsley Faulkner. Many of the portraits are of former College presidents. The presidents have often been painted by the leading artist of the day, many of whom won the Archibald Prize. There are many connections between surgeons and the Archibald Prize, the most prestigious award in Australian art.

  5. Dannie Heineman Prize for CERN theorist

    CERN Multimedia

    2003-01-01

    CERN's Gabriele Veneziano, is the recipient of the Dannie Heineman Prize for Mathematical Physics 2004, which he receives "for his pioneering discoveries in dual resonance models which, partly through his own efforts, have developed into string theory and a basis for the quantum theory of gravity". The prize was established in 1959 by the Heineman Foundation for Research, Educational, Charitable, and Scientific Purposes, and is administered jointly by the American Physical Society and the American Institute of Physics.

  6. How the 1906 Nobel Prize in Physiology or Medicine was shared between Golgi and Cajal.

    Science.gov (United States)

    Grant, Gunnar

    2007-10-01

    In 1906 the Nobel Prize in Physiology or Medicine was shared between Camillo Golgi and Ramón y Cajal in recognition of their work on the structure of the nervous system. Golgi's most impressive contribution was his method, described in 1873. This was applied in studies of the cerebellum, the olfactory bulb, hippocampus and the spinal cord. These studies together with his earlier work were included in his Opera Omnia, published in 1903. His method was highly praised by Cajal. His adherence to the reticular theory was opposed by Cajal, however, who had spelled out the neuron theory already in the late 1800s. Cajal's extraordinary contributions to the structure of the nervous system, based largely on the Golgi method and Ehrlich's methylene blue stain, were published in his Textura del Sistema Nerviosa de Hombre y de los Vertebrados, three volumes published from 1897 to 1904. Documents from the Nobel Archives reveal that Kölliker, Retzius and Fürst were the ones who proposed Golgi and Cajal for a shared prize. Golgi was nominated by Hertwig, as well. Cajal was proposed by Ziehen and Holmgren, and also by Retzius, as an alternative to a shared prize. Holmgren, who was commissioned to write the report to the Nobel Committee, found Cajal far superior to Golgi. Sundberg, asked for another evaluation, was more positive to Golgi's contributions than Holmgren. Gadelius supported Holmgren's views. The final vote gave a majority for a shared prize. The prize ceremony and the lectures were described in detail in Cajal's autobiography.

  7. Nuclear power - the glittering prizes

    Energy Technology Data Exchange (ETDEWEB)

    Horton, C.C.

    The paper on the benefits of nuclear power is based on a lecture given for the Institution of Nuclear Engineers, London, 1986. Suggestions for short term benefits include a clean environment and a cheap energy source, whereas suggestions for long term benefits include freedom from want in the world and avoidance of 'energy wars'. These benefits are discussed along with alternative energy sources, the financial savings to be saved from nuclear power, world energy wealth, depletion of world energy reserves, and risks due to radiation exposure.

  8. Nobel Prize for blue LEDs

    Science.gov (United States)

    Kraftmakher, Yaakov

    2015-05-01

    A brief review of lighting technologies is presented. Unavoidable restrictions for incandescent light bulbs caused by the Planck distribution and properties of the human eye are illustrated. The efficiency and luminous efficacy of thermal radiation are calculated for various temperatures; the results clearly show the limitations for thermal radiators. The only way to overcome these limitations is using non-thermal radiators, such as fluorescent lamps and light-emitting diodes (LEDs). Unique advantages of LEDs undoubtedly made a revolution in this field. A crucial element of this progress is the blue LEDs (Nobel Prize 2014). Some experiments with a blue and a green LED are described: (i) the luminescence triggered in a green-yellow phosphor inside a white LED by the blue LED; (ii) radiant spectra and ‘efficiency droop’ in the LEDs; (iii) modulation of the blue LED up to 4 MHz; and (iv) the h/e ratio from the turn-on voltage of the green LED. The experiments are suitable for undergraduate laboratories and usable as classroom demonstrations.

  9. Eugene Paul Wigner's Nobel Prize

    CERN Document Server

    Kim, Y S

    2016-01-01

    In 1963, Eugene Paul Wigner was awarded the Nobel Prize in Physics for his contributions to the theory of the atomic nucleus and the elementary particles, particularly through the discovery and application of fundamental symmetry principles. There are no disputes about this statement. On the other hand, there still is a question of why the statement did not mention Wigner's 1939 paper on the Lorentz group, which was regarded by Wigner and many others as his most important contribution in physics. By many physicists, this paper was regarded as a mathematical exposition having nothing to do with physics. However, it has been more than one half century since 1963, and it is of interest to see what progress has been made toward understanding physical implications of this paper and its historical role in physics. Wigner in his 1963 paper defined the subgroups of the Lorentz group whose transformations do not change the four-momentum of a given particle, and he called them the little groups. Thus, Wigner's little g...

  10. Reduced Rank Regression

    DEFF Research Database (Denmark)

    Johansen, Søren

    2008-01-01

    The reduced rank regression model is a multivariate regression model with a coefficient matrix with reduced rank. The reduced rank regression algorithm is an estimation procedure, which estimates the reduced rank regression model. It is related to canonical correlations and involves calculating e...... eigenvalues and eigenvectors. We give a number of different applications to regression and time series analysis, and show how the reduced rank regression estimator can be derived as a Gaussian maximum likelihood estimator. We briefly mention asymptotic results......The reduced rank regression model is a multivariate regression model with a coefficient matrix with reduced rank. The reduced rank regression algorithm is an estimation procedure, which estimates the reduced rank regression model. It is related to canonical correlations and involves calculating...

  11. Dannie Heineman Prize for Mathematical Physics Prize Lecture: Correlation Functions in Integrable Models: Ising Model and Monodromy Preserving Deformation

    Science.gov (United States)

    Miwa, Tetsuji

    2013-03-01

    Studies on integrable models in statistical mechanics and quantum field theory originated in the works of Bethe on the one-dimensional quantum spin chain and the work of Onsager on the two-dimensional Ising model. I will talk on the discovery in 1977 of the link between quantum field theory in the scaling limit of the two-dimensional Ising model and the theory of monodromy preserving linear ordinary differential equations. This work was the staring point of our journey with Michio Jimbo in integrable models, the journey which finally led us to the exact results on the correlation functions of quantum spin chains in 1992.

  12. Dannie Heineman Prize for Mathematical Physics Prize Lecture: Correlation Functions in Integrable Models II: The Role of Quantum Affine Symmetry

    Science.gov (United States)

    Jimbo, Michio

    2013-03-01

    Since the beginning of 1980s, hidden infinite dimensional symmetries have emerged as the origin of integrability: first in soliton theory and then in conformal field theory. Quest for symmetries in quantum integrable models has led to the discovery of quantum groups. On one hand this opened up rapid mathematical developments in representation theory, combinatorics and other fields. On the other hand it has advanced understanding of correlation functions of lattice models, leading to multiple integral formulas in integrable spin chains. We shall review these developments which continue up to the present time.

  13. A Geminoid as Lecturer

    DEFF Research Database (Denmark)

    Abildgaard, Julie Rafn; Schärfe, Henrik

    2012-01-01

    In this paper we report our findings from an experiment with the teleoperated android Geminoid-DK. The geminoid took up the role of a university lecturer and delivered a 45 minute lecture in front of 150 freshmen students at Aalborg University. While considering the role of the geminoid in this e......In this paper we report our findings from an experiment with the teleoperated android Geminoid-DK. The geminoid took up the role of a university lecturer and delivered a 45 minute lecture in front of 150 freshmen students at Aalborg University. While considering the role of the geminoid...

  14. ALICE physicists receive 2014 Lise Meitner Prize

    CERN Multimedia

    Katarina Anthony

    2014-01-01

    On Wednesday, 3 September, four ALICE physicists were presented with the European Physical Society's 2014 Lise Meitner Prize for their outstanding contributions to nuclear physics (see here).   ALICE collaboration members Johanna Stachel (Heidelberg University, Germany), Peter Braun-Munzinger (GSI, Germany), Paolo Giubellino (INFN Turin, Italy, and CERN) and Jürgen Schukraft (CERN) were presented with their awards at a private ceremony held in the Globe of Science and Innovation. In addition to members of the ALICE collaboration, the ceremony was attended by members of the CERN Management including the Director-General, Rolf Heuer, as well as the EPS Nuclear Physics Board Chair, Douglas MacGregor, and the EPS Lise Meitner Prize Committee Chair, Victor Zamfir. For more information, please see "EPS honours CERN's heavy-ion researchers".  From left to right: Douglas MacGregor (EPS); Prize recipients Jürgen Schukraft,&a...

  15. Stephen Hawking bags big new 3m physics prize

    Science.gov (United States)

    Johnston, Hamish

    2013-01-01

    A massive 3m in prize money has gone to the British cosmologist Stephen Hawking for his work on black holes, quantum gravity and the early universe. The award is one of two "special fundamental physics prizes" from the Fundamental Physics Prize Foundation, which was set up earlier this year by the Russian physicist-turned-entrepreneur Yuri Milner.

  16. 78 FR 40132 - Wave Energy Converter Prize Administration Webinar

    Science.gov (United States)

    2013-07-03

    ... alternative strategies and approaches for the prize administration. A multi stage-gate challenge structure... of Energy Efficiency and Renewable Energy Wave Energy Converter Prize Administration Webinar AGENCY... Energy Converter Prize Administration''. The Office is planning a webinar in advance of any potential FOA...

  17. 29 CFR 778.330 - Prizes or contest awards generally.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Prizes or contest awards generally. 778.330 Section 778.330 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR STATEMENTS OF GENERAL POLICY OR INTERPRETATION NOT DIRECTLY RELATED TO REGULATIONS OVERTIME COMPENSATION Special Problems Prizes As Bonuses § 778.330 Prizes...

  18. Row bubbles up over particle prize

    CERN Multimedia

    Chalmers, Matthew

    2009-01-01

    "The European Physical Society (EPS) has defended its handling of the 2009 prize for high-energy and particle physics despite complaints that the awarding committee overlooked a vital scientific contribution to the prize-winning work. The biennial award, worth SwFr 5000, was given to collaborators on the Gargamelle bubble-chamber experiment at Cern for their descovery in 1973 of the "weak neutral current" - one of the ways in which the weak nuclear force is mediated between fundamental particles" (0.75 page)

  19. Two Nobel Prize winners in two days

    CERN Multimedia

    2006-01-01

    Living legend of physics, Professor Chen Ning Yang, delivered his CERN Colloquium in the Main Auditorium on 12th October (see photo). His numerous contributions to physics include the famous Yang-Mills theory, which underlies the Standard Model of particle physics, and the prediction of parity violation in weak interactions, for which he shared the Nobel prize with T. D. Lee in 1957. The day before, another Nobel laureate, Norman Ramsey, gave a TH Exceptional Seminar in the same auditorium. Ramsey shared the Nobel Prize with Hans G. Dehmelt and Wolfgang Paul in 1989 for developments in atomic precision spectroscopy.

  20. Academic Training Lecture - Regular lecture programme

    CERN Multimedia

    PH Department

    2011-01-01

    Wednesday 28, Thursday 29 and Friday 30 September 2011 Supersymmetric Recipes by Prof. Ben Allanech / University of Cambridge, UK  from 11:00 to 12:00 (Europe/Zurich) at CERN ( Main Auditorium, Bldg. 500 ) In these lectures, I shall describe the theory of supersymmetry accessible to people with a knowledge of basic quantum field theory. The lectures will contain recipes of how to calculate which interactions (and which special relations) are in supersymmetry, without providing detailed proofs of where they come from. We shall also cover: motivation for weak-scale supersymmetry and the minimal supersymmetric standard model.

  1. Ranking Operations Management conferences

    NARCIS (Netherlands)

    Steenhuis, H.J.; de Bruijn, E.J.; Gupta, Sushil; Laptaned, U

    2007-01-01

    Several publications have appeared in the field of Operations Management which rank Operations Management related journals. Several ranking systems exist for journals based on , for example, perceived relevance and quality, citation, and author affiliation. Many academics also publish at conferences

  2. A randomized trial comparing digital and live lecture formats [ISRCTN40455708

    Directory of Open Access Journals (Sweden)

    Laird-Fick Heather S

    2004-11-01

    Full Text Available Abstract Background Medical education is increasingly being conducted in community-based teaching sites at diverse locations, making it difficult to provide a consistent curriculum. We conducted a randomized trial to assess whether students who viewed digital lectures would perform as well on a measure of cognitive knowledge as students who viewed live lectures. Students' perceptions of the digital lecture format and their opinion as whether a digital lecture format could serve as an adequate replacement for live lectures was also assessed. Methods Students were randomized to either attend a lecture series at our main campus or view digital versions of the same lectures at community-based teaching sites. Both groups completed the same examination based on the lectures, and the group viewing the digital lectures completed a feedback form on the digital format. Results There were no differences in performance as measured by means or average rank. Despite technical problems, the students who viewed the digital lectures overwhelmingly felt the digital lectures could replace live lectures. Conclusions This study provides preliminary evidence digital lectures can be a viable alternative to live lectures as a means of delivering didactic presentations in a community-based setting.

  3. Lectures on combustion theory

    Energy Technology Data Exchange (ETDEWEB)

    Burstein, S.Z.; Lax, P.D.; Sod, G.A. (eds.)

    1978-09-01

    Eleven lectures are presented on mathematical aspects of combustion: fluid dynamics, deflagrations and detonations, chemical kinetics, gas flows, combustion instability, flame spread above solids, spark ignition engines, burning rate of coal particles and hydrocarbon oxidation. Separate abstracts were prepared for three of the lectures. (DLC)

  4. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel 73127

    2001-01-01

    28, 29, 30, 31 May and 1 June REGULAR LECTURE PROGRAMME From 11:00 hrs - Main Auditorium bldg. 500 Quantum computing and Quantum cryptography T. Hey / University of Southampton, GB, and D. Ross / CERN-TH This course will give both an overview and a detailed introduction to quantum computing and quantum cryptography. The first lecture will survey the field, starting from its origins in Feyman's lecture in 1981. The next three lectures will explain in detail the relevance of Bell states and the workings of Grover's Quantum Search and Shor's quantum factorization algorithms. In addition, an explanation of quantum teleportation will be given. The last lecture will survey the recent progress towards realizing working quantum computers and quantum cryptographic systems.

  5. Venture Leaders Prize for innovative technology projects

    CERN Document Server

    2006-01-01

    In co-operation with the GEBERT RÜF FOUNDATION and the Ernest & Young Entrepreneur of the Year Award, venturelab will be presenting the Venture Leaders Prize. The Venture Leaders Prize, which is the new guise of the NETS (New Entrepreneurs in Technology and Science) Prize, will give twenty research entrepreneurs with projects to develop innovative technologies the opportunity to win the chance of participating in a programme to assist them in starting up their companies. The winners will go to spend 10 days in the Boston area (United States) where they will take part in a development programme for their project, which will include an entrepreneurship course, opportunities to meet start-up companies and financing experts, etc. This prize has already spawned many companies such as id Quantique, Selexis or ABMI which have contributed to the economic development of regions, particularly in French-speaking Switzerland. The competition is open to students and scientists from all fields, who would like to s...

  6. 2016 Nobel Prize in Chemistry1

    Indian Academy of Sciences (India)

    The Nobel Prize in Chemistry for the year 2016 was awardedto three illustrious chemists, Professors Jean-Pierre Sauvage,Sir Fraser Stoddart, and Ben Feringa. Pioneering works ofthese chemists on designing molecules, chemically synthesizingthem, and extracting a work out of such designedmoleculesopen-up a new ...

  7. Innate Immunity and the 2011 Nobel Prize

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 17; Issue 10. Innate Immunity and the 2011 Nobel Prize. Mukta Deobagkar Lele Chetana Bhaskarla Rajkumar Dhanaraju Manikandan Ponnusamy Dipankar Nandi. General Article Volume 17 Issue 10 October 2012 pp 974-995 ...

  8. L Prize Drives Technology Innovation, Energy Savings

    Energy Technology Data Exchange (ETDEWEB)

    None

    2014-04-30

    Fact sheet that provides an overview of DOE's L Prize competition, which challenges industry to develop high-quality, high-efficiency SSL products to replace 60W incandescent and PAR38 halogen light bulbs, and highlights the competition's first 60W winner from Philips Lighting North America.

  9. Information and Announcements The Breakthrough Prize

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 19; Issue 10. Breakthrough Prize. B Sury Rajaram Nityananda Dipshikha Chakravortty. Information and Announcements Volume 19 Issue 10 October 2014 pp 966-969. Fulltext. Click here to view fulltext PDF. Permanent link:

  10. Chemistry Nobel Prize 2002-Mass Spectrometry

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 8; Issue 4. Chemistry Nobel Prize 2002 - Mass Spectrometry. M Vairamani. Research News Volume 8 Issue 4 April 2003 pp 69-76. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/008/04/0069-0076 ...

  11. ALICE physicists receive 2014 Lise Meitner Prize

    CERN Multimedia

    Jeanneret, Guillaume

    2014-01-01

    September 3rd, 2014: ALICE collaboration members Johanna Stachel (Heidelberg University, Germany), Peter Braun-Munzinger (GSI, Germany), Paolo Giubellino (INFN Turin, Italy, and CERN) and Jürgen Schukraft (CERN) were presented the 2014 Lise Meitner Prize at a private ceremony held in the Globe of Science and Innovation.

  12. Nobel Prize in Physiology or Medicine 1999

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 5; Issue 5. Nobel Prize in Physiology or Medicine 1999. Utpal Tatu. Research News Volume 5 Issue 5 May 2000 pp 91-95. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/005/05/0091-0095 ...

  13. Nobel Prize in Physiology or Medicine 20161

    Indian Academy of Sciences (India)

    The Nobel Prize in Physiology or Medicine 2016 was awardedto Yoshinori Ohsumi of the Tokyo Institute of Technology,Japan, for his discoveries of mechanisms for autophagy [1]. Author Affiliations. Shekhar C Mande1 Jyoti Rao1. National Centre for Cell Science, Ganeshkhind, Pune 411 007, India. Resonance – Journal of ...

  14. Nobel Prizes and the Quantum Theory

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 4; Issue 2. Nobel Prizes and the Quantum Theory. N Mukunda. Classics Volume 4 Issue 2 February 1999 pp 91-91. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/004/02/0091-0091. Author Affiliations.

  15. Nobel Prize in Physiology or Medicine 20161

    Indian Academy of Sciences (India)

    an interest in studying. Mycobacterium tuberculosis. Jyoti Rao, a scientist at. NCCS, Pune, is a microbiologist with an interest in ecology and sociobiology, and exploring the interface of science and art. The Nobel Prize in Physiology or Medicine 2016 was awarded to Yoshinori Ohsumi of the Tokyo Institute of Technology,.

  16. The 2009 Nobel Prize in Physics

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 15; Issue 8. The 2009 Nobel Prize in Physics - Honoring Achievements in Optics that have Changed Modern Life. Vasant Natarajan. General Article Volume 15 Issue 8 August 2010 pp 723-732 ...

  17. The Nobel Prize in Physics 1999

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 5; Issue 2. The Nobel Prize in Physics 1999. Rohini M Godbole. General Article Volume 5 Issue 2 February 2000 pp 16-25. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/005/02/0016-0025 ...

  18. Nobel Prize in Physiology or Medicine

    Science.gov (United States)

    ... Privacy Policy Technical Support For Developers Copyright Follow Facebook Instagram Twitter YouTube Nobelprize.org Monthly Nobel Prize App Contact | Press | Sitemap | FAQ  | Terms Copyright © Nobel Media AB 2018 Join us: Contact E-mail Us Press Newsroom Sitemap A-Z Index ...

  19. NVVC/NHJ Durrer Prizes 2012.

    Science.gov (United States)

    van der Wall, E E; Schalij, M J; Umans, V A W M

    2013-06-01

    At the annual Spring Congress of the NVVC the Durrer prizes were awarded to the authors of the best original/review articles published in the year 2012, one paper being more basically-oriented and one paper being more clinically-oriented. This annual tradition exists already since the year 2006.

  20. NVVC/NHJ Durrer prizes 2013.

    Science.gov (United States)

    van der Wall, E E; Umans, V A W M

    2014-05-01

    At the annual Spring Congress of the NVVC, the Durrer prizes were awarded to the authors of two of the best original/review articles published in the year 2013, one paper being more basically oriented and one paper being more clinically oriented. This annual tradition has existed since the year 2006.

  1. NVVC/NHJ Durrer prizes 2015.

    Science.gov (United States)

    van der Wall, E E

    2016-05-01

    At the annual 2016 Spring Congress of the NVVC, the Durrer prizes were awarded to the authors of two of the best original articles published in the year 2015, one paper being more basically oriented and one paper being more clinically oriented. This annual tradition has existed since the year 2006.

  2. NVVC/NHJ Durrer prizes 2014.

    Science.gov (United States)

    Wall, E E van der; Umans, V A W M

    2015-06-01

    At the annual 2015 Spring Congress of the NVVC, the Durrer prizes were awarded to the authors of two of the best original/review articles published in the year 2014, one paper being more basically oriented and one paper being more clinically oriented. This has been an annual tradition since the year 2006.

  3. The Nobel Prize in Physics-1996

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 1; Issue 12. The Nobel Prize in Physics - 1996. R Srinivasan. Research News Volume 1 Issue 12 December 1996 pp 65-68. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/001/12/0065-0068 ...

  4. Sparse structure regularized ranking

    KAUST Repository

    Wang, Jim Jing-Yan

    2014-04-17

    Learning ranking scores is critical for the multimedia database retrieval problem. In this paper, we propose a novel ranking score learning algorithm by exploring the sparse structure and using it to regularize ranking scores. To explore the sparse structure, we assume that each multimedia object could be represented as a sparse linear combination of all other objects, and combination coefficients are regarded as a similarity measure between objects and used to regularize their ranking scores. Moreover, we propose to learn the sparse combination coefficients and the ranking scores simultaneously. A unified objective function is constructed with regard to both the combination coefficients and the ranking scores, and is optimized by an iterative algorithm. Experiments on two multimedia database retrieval data sets demonstrate the significant improvements of the propose algorithm over state-of-the-art ranking score learning algorithms.

  5. ACADEMIC TRAINING LECTURES-QUESTIONNAIRE: SUGGEST AND WIN!

    CERN Multimedia

    2003-01-01

    Its time to plan for the 2003-2004 lecture series. From today until April 25 you have the chance to give your contribution to planning for next year's Academic Training Lectures Series. At the web site : http://cern.ch/Academic.Training/questionnaire you will find questionnaires proposing topics in high energy physics, applied physics and science and society. Answering the questionnaire will help ensure that the selected topics are as close as possible to your interests. In particular requests and comments from students will be much appreciated. To encourage your contribution, the AT Committee will reward one lucky winner with a small prize, a 50 CHF coupon for a book purchase at the CERN bookshop.

  6. ACADEMIC TRAINING LECTURES-QUESTIONNAIRE: SUGGEST AND WIN !

    CERN Multimedia

    2003-01-01

    Its time to plan for the 2003-2004 lecture series. From today until April 25 you have the chance to give your contribution to planning for next year's Academic Training Lectures Series. At the web site : http://cern.ch/Academic.Training/questionnaire you will find questionnaires proposing topics in high energy physics, applied physics and science and society. Answering the questionnaire will help ensure that the selected topics are as close as possible to your interests. In particular requests and comments from students will be much appreciated. To encourage your contribution, the AT Committee will reward one lucky winner with a small prize, a 50 CHF coupon for a book purchase at the CERN bookshop.

  7. ACADEMIC TRAINING LECTURE

    CERN Document Server

    Academic Training; Tel. 73127

    2001-01-01

    12, 13, 14, 15 & 16 March REGULAR LECTURE PROGRAMME From 11:00 hrs - Main Auditorium bldg. 500 Telecommunication for the future Rob Parker / CERN-IT Few fields have experienced such a high level of technical advance over the last few decades as that of telecommunications. This lecture series will track the evolution of telecommunications systems since their inception, and consider how technology is likely to advance over the next years. A personal view will also be given of the effect of these innovations on our work and leisure activities.The lecture series will be aimed at an audience with no specific technical knowledge of telecommunications.

  8. Stress and coping in lecturing, and the stability of responses across pratice

    NARCIS (Netherlands)

    Houtman, I.L.D.; Bakker, F.C.

    1991-01-01

    The central issues of the present paper are the responses to the stress of lecturing in a standardized situation, and the adaptation to this stressor across a period of real-life lecturing practice. Special attention is given to the stability of rank-order in the physiological and psychological

  9. Feynman Lectures on Computation

    CERN Document Server

    Feynman, Richard Phillips; Allen, Robin W

    1999-01-01

    "When, in 1984-86, Richard P. Feynman gave his famous course on computation at the California Institute of Technology, he asked Tony Hey to adapt his lecture notes into a book. Although led by Feynman,"

  10. Lectures on Dispersion Theory

    Science.gov (United States)

    Salam, A.

    1956-04-01

    Lectures with mathematical analysis are given on Dispersion Theory and Causality and Dispersion Relations for Pion-nucleon Scattering. The appendix includes the S-matrix in terms of Heisenberg Operators. (F. S.)

  11. First Calderón Prize

    Science.gov (United States)

    Rundell, William; Somersalo, Erkki

    2008-07-01

    The Inverse Problems International Association (IPIA) awarded the first Calderón Prize to Matti Lassas for his outstanding contributions to the field of inverse problems, especially in geometric inverse problems. The Calderón Prize is given to a researcher under the age of 40 who has made distinguished contributions to the field of inverse problems broadly defined. The first Calderón Prize Committee consisted of Professors Adrian Nachman, Lassi Päivärinta, William Rundell (chair), and Michael Vogelius. William Rundell For the Calderón Prize Committee Prize ceremony The ceremony awarding the Calderón Prize. Matti Lassas is on the left. He and William Rundell are on the right. Photos by P Stefanov. Brief Biography of Matti Lassas Matti Lassas was born in 1969 in Helsinki, Finland, and studied at the University of Helsinki. He finished his Master's studies in 1992 in three years and earned his PhD in 1996. His PhD thesis, written under the supervision of Professor Erkki Somersalo was entitled `Non-selfadjoint inverse spectral problems and their applications to random bodies'. Already in his thesis, Matti demonstrated a remarkable command of different fields of mathematics, bringing together the spectral theory of operators, geometry of Riemannian surfaces, Maxwell's equations and stochastic analysis. He has continued to develop all of these branches in the framework of inverse problems, the most remarkable results perhaps being in the field of differential geometry and inverse problems. Matti has always been a very generous researcher, sharing his ideas with his numerous collaborators. He has authored over sixty scientific articles, among which a monograph on inverse boundary spectral problems with Alexander Kachalov and Yaroslav Kurylev and over forty articles in peer reviewed journals of the highest standards. To get an idea of the wide range of Matti's interests, it is enough to say that he also has three US patents on medical imaging applications. Matti is

  12. Maximum Waring ranks of monomials

    OpenAIRE

    Holmes, Erik; Plummer, Paul; Siegert, Jeremy; Teitler, Zach

    2013-01-01

    We show that monomials and sums of pairwise coprime monomials in four or more variables have Waring rank less than the generic rank, with a short list of exceptions. We asymptotically compare their ranks with the generic rank.

  13. How to Rank Journals.

    Science.gov (United States)

    Bradshaw, Corey J A; Brook, Barry W

    2016-01-01

    There are now many methods available to assess the relative citation performance of peer-reviewed journals. Regardless of their individual faults and advantages, citation-based metrics are used by researchers to maximize the citation potential of their articles, and by employers to rank academic track records. The absolute value of any particular index is arguably meaningless unless compared to other journals, and different metrics result in divergent rankings. To provide a simple yet more objective way to rank journals within and among disciplines, we developed a κ-resampled composite journal rank incorporating five popular citation indices: Impact Factor, Immediacy Index, Source-Normalized Impact Per Paper, SCImago Journal Rank and Google 5-year h-index; this approach provides an index of relative rank uncertainty. We applied the approach to six sample sets of scientific journals from Ecology (n = 100 journals), Medicine (n = 100), Multidisciplinary (n = 50); Ecology + Multidisciplinary (n = 25), Obstetrics & Gynaecology (n = 25) and Marine Biology & Fisheries (n = 25). We then cross-compared the κ-resampled ranking for the Ecology + Multidisciplinary journal set to the results of a survey of 188 publishing ecologists who were asked to rank the same journals, and found a 0.68-0.84 Spearman's ρ correlation between the two rankings datasets. Our composite index approach therefore approximates relative journal reputation, at least for that discipline. Agglomerative and divisive clustering and multi-dimensional scaling techniques applied to the Ecology + Multidisciplinary journal set identified specific clusters of similarly ranked journals, with only Nature & Science separating out from the others. When comparing a selection of journals within or among disciplines, we recommend collecting multiple citation-based metrics for a sample of relevant and realistic journals to calculate the composite rankings and their relative uncertainty windows.

  14. PRIze{sup TM} 1.2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-10-01

    PRIze{sup TM} 1.2 is a computer program that evaluates the improved oil recovery (IOR) potential of petroleum reservoirs including the use of horizontal wells. It was created in 1992 and has since been used in over 800 reservoir evaluations. The tool provides information on the feasibility of IOR processes based on reservoir parameters. PRIze{sup TM} makes predictions for chemical, gas injection and thermal IOR processes based on both vertical and horizontal wells. The program provides a uniform data entry screen that allows the user to input 42 average values of geological parameters, fluid properties and oil production mechanism information into a data file. The data can be used to provide a production forecast, and enable the user to establish, to a first order approximation, the economic viability of a given process.

  15. Two Nobel Prizes connected to CERN

    CERN Multimedia

    2003-01-01

    The 2003 Nobel Prizes in Physics and in Physiology or Medicine, announced last week, both have connections with particle physics and CERN. Alexei Abrikosov, Vitaly Ginzburg and Anthony Leggett have received the prize in physics for their "pioneering contributions to the theory of superconductors and superfluids". The most important superconducting materials technically have proved to be those known as type II superconductors, which allow superconductivity and magnetism to exist at the same time and remain superconductive in high magnetic fields. The coils for the superconducting magnets in CERN's Large Hadron Collider are made from niobium-titanium alloy - a type II superconductor. The LHC will operate thanks to magnets made of type II superconductors. Here, superconducting cables for the LHC are on display during a VIP visit.Abrikosov, who is now at the Argonne National Laboratory, was working at the Kapitsa Institute for Physical Problems in his native Moscow when he succeeded in formula...

  16. Gustav-Hertz-Prize for CERN Physicist

    CERN Multimedia

    2004-01-01

    Klaus Blaum, of GSI Darmstadt and project leader of the ISOLTRAP experiment at CERN, will receive the 2004 Gustav-Hertz-Prize for his outstanding work on the mass determination of unstable atomic nuclei. Blaum extended the measuring capability of the ISOLTRAP experiment at the ISOLDE facility, which studies short-lived isotopes, by installing a source of carbon clusters. Using these carbon clusters as mass reference allows researchers to obtain higher-precision and absolute atomic mass measurements which are important to understand the weak interaction and the synthesis of chemical elements. The Gustav-Hertz-Prize is awarded to outstanding young physicists and is endowed with 7500 euro. It will be awarded at the Spring Conference of the German Physical Society in Munich on 24 March.

  17. EPS HEPP Prize 2013: Certificate and Medal

    CERN Multimedia

    Rao, Achintya

    2013-01-01

    The 2013 High Energy and Particle Physics Prize, for an outstanding contribution to High Energy Physics, is awarded to the ATLAS and CMS collaborations, "for the discovery of a Higgs boson, as predicted by the Brout-Englert-Higgs mechanism", and to Michel Della Negra, Peter Jenni, and Tejinder Virdee, "for their pioneering and outstanding leadership roles in the making of the ATLAS and CMS experiments".

  18. The Abel Prize 2008-2012

    CERN Document Server

    Piene, Ragni

    2014-01-01

    Covering the years 2008-2012, this book profiles the life and work of recent winners of the Abel Prize:   ·         John G. Thompson and Jacques Tits, 2008 ·         Mikhail Gromov, 2009 ·         John T. Tate Jr., 2010 ·         John W. Milnor, 2011 ·         Endre Szemerédi, 2012. The profiles feature autobiographical information as well as a description of each mathematician's work. In addition, each profile contains a complete bibliography, a curriculum vitae, as well as photos — old and new. As an added feature, interviews with the Laureates are presented on an accompanying web site (http://extras.springer.com/).   The book also presents a  history of the Abel Prize written by the historian Kim Helsvig, and includes a facsimile of a letter from Niels Henrik Abel, which is transcribed, translated into English, and placed into historical perspective by Christian Skau.    This book follows on The Abel Prize: 2003-2007, The First Five Years (Springer, 2010),...

  19. Academic rankings: an approach to a Portuguese ranking

    OpenAIRE

    Bernardino, Pedro; Marques,Rui

    2009-01-01

    The academic rankings are a controversial subject in higher education. However, despite all the criticism, academic rankings are here to stay and more and more different stakeholders use rankings to obtain information about the institutions’ performance. The two most well-known rankings, The Times and the Shanghai Jiao Tong University rankings have different methodologies. The Times ranking is based on peer review, whereas the Shanghai ranking has only quantitative indicators and is mainly ba...

  20. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    ACADEMIC TRAINING LECTURE 1, 2, 3, 4 and 5 October LECTURES FOR POSTGRADUATE STUDENTS From 10:00 hrs - Main Auditorium bldg. 500 1 Introduction to particle accelerators E.J.N. Wilson / CERN-AC , Head of the CERN Accelerator School This new series of lectures is intended for anyone with a technical or scientific background who would like to become familiar with the principles of accelerator design. It is a complement to last year's course and includes new lectures on present day accelerators, and their applications as well as colliders and neutrino factories. Beam dynamics, which was treated at length in last year's course, has been compressed into one lecture, intended as revision for those who followed earlier courses and an introduction for newcomers to the field. The course should not be missed by those who will attend the CAS Intermediate Accelerator School in Seville. 1-10 10:00 Present-day Accelerators 11:00 - Beam Dynamics 2-10 10:00 Accelerating Cavities 11:00 - Non-linear Dynamics 3-10 10:00 E...

  1. Lecture on beam instabilities

    Energy Technology Data Exchange (ETDEWEB)

    Chao, A.

    1999-12-21

    These lectures treat some of the common collective beam instability effects encountered in accelerators. In choosing the material for these lectures, it is attempted to introduce this subject with a more practical approach, instead of a more theoretical approach starting with first principles. After introducing the terminologies, emphasis will be placed on how to apply the lecture material to perform calculations and to make estimates of various instability effects. In the first half of the lectures, after briefly introducing the concepts of impedance and wake field, the authors will discuss a selected list of formulas for the impedances of various accelerator components. Detailed derivations are omitted, allowing time for the students to think through the process of how to apply the knowledge learned. The list of impedances to be covered include: space charge, resistive wall, resonator, wall roughness, and small perturbation on the vacuum chamber wall. Assuming impedances are known, the second half of the lectures addresses the question of how to calculate the power of beam heating, the growth rates, and the thresholds for a list of selected beam instability effects. Again with minimal detailed derivations, the aim is to introduce a collection of formulas, and apply them to linear as well as circular accelerators. The list of beam instability effects to be covered include: loss factor, beam break-up, BNS damping, bunch lengthening, resistive wall instability, head-tail instability, longitudinal head-tail instability, Landau damping, microwave instability, and mode coupling instability.

  2. Albert Einstein memorial lectures

    CERN Document Server

    Mechoulam, Raphael; The Israel Academy for Sciences and Humanities

    2012-01-01

    This volume consists of a selection of the Albert Einstein Memorial Lectures presented annually at the Israel Academy of Sciences and Humanities. Delivered by eminent scientists and scholars, including Nobel laureates, they cover a broad spectrum of subjects in physics, chemistry, life science, mathematics, historiography and social issues. This distinguished memorial lecture series was inaugurated by the Israel Academy of Sciences and Humanities following an international symposium held in Jerusalem in March 1979 to commemorate the centenary of Albert Einstein's birth. Considering that Einstein's interests, activities and influence were not restricted to theoretical physics but spanned broad fields affecting society and the welfare of humankind, it was felt that these memorial lectures should be addressed to scientists, scholars and erudite laypersons rather than to physicists alone.

  3. Lectures on Chevalley groups

    CERN Document Server

    Steinberg, Robert

    2016-01-01

    Robert Steinberg's Lectures on Chevalley Groups were delivered and written during the author's sabbatical visit to Yale University in the 1967-1968 academic year. The work presents the status of the theory of Chevalley groups as it was in the mid-1960s. Much of this material was instrumental in many areas of mathematics, in particular in the theory of algebraic groups and in the subsequent classification of finite groups. This posthumous edition incorporates additions and corrections prepared by the author during his retirement, including a new introductory chapter. A bibliography and editorial notes have also been added. This is a great unsurpassed introduction to the subject of Chevalley groups that influenced generations of mathematicians. I would recommend it to anybody whose interests include group theory. -Efim Zelmanov, University of California, San Diego Robert Steinberg's lectures on Chevalley groups were given at Yale University in 1967. The notes for the lectures contain a wonderful exposition of ...

  4. Lectures for CERN pensioners

    CERN Multimedia

    GS Department

    2009-01-01

    The CERN Medical Service and the Pensioners Association are pleased to invite CERN pensioners to a series of lectures given by professors and specialists from the Teaching Hospitals and the Faculty of Medicine of the University of Geneva on the following topic: PROMOTION OF OPTIMUM BRAIN AGEING The lectures will take place in the Main CERN Auditorium (Building 60) from 2.30 p.m. to 4.30 p.m. on the following dates: Thursday 15 January 2009: Diagnosing and treating Alzheimer’s disease Pr Gabriel GOLD Wednesday 25 February 2009: What is the brain reserve? Speaker’s name to be announced at a later date. The lectures will be given in French, with transparencies in English, and will be followed by a wide-ranging debate with the participants. CERN Medical Service - Pensioners Association - CERN-ESO (GAC-EPA)

  5. Lectures on functor homology

    CERN Document Server

    Touzé, Antoine

    2015-01-01

    This book features a series of lectures that explores three different fields in which functor homology (short for homological algebra in functor categories) has recently played a significant role. For each of these applications, the functor viewpoint provides both essential insights and new methods for tackling difficult mathematical problems. In the lectures by Aurélien Djament, polynomial functors appear as coefficients in the homology of infinite families of classical groups, e.g. general linear groups or symplectic groups, and their stabilization. Djament’s theorem states that this stable homology can be computed using only the homology with trivial coefficients and the manageable functor homology. The series includes an intriguing development of Scorichenko’s unpublished results. The lectures by Wilberd van der Kallen lead to the solution of the general cohomological finite generation problem, extending Hilbert’s fourteenth problem and its solution to the context of cohomology. The focus here is o...

  6. Ranking Economic History Journals

    DEFF Research Database (Denmark)

    Di Vaio, Gianfranco; Weisdorf, Jacob Louis

    This study ranks - for the first time - 12 international academic journals that have economic history as their main topic. The ranking is based on data collected for the year 2007. Journals are ranked using standard citation analysis where we adjust for age, size and self-citation of journals. We...... also compare the leading economic history journals with the leading journals in economics in order to measure the influence on economics of economic history, and vice versa. With a few exceptions, our results confirm the general idea about what economic history journals are the most influential...

  7. Ranking economic history journals

    DEFF Research Database (Denmark)

    Di Vaio, Gianfranco; Weisdorf, Jacob Louis

    2010-01-01

    This study ranks-for the first time-12 international academic journals that have economic history as their main topic. The ranking is based on data collected for the year 2007. Journals are ranked using standard citation analysis where we adjust for age, size and self-citation of journals. We also...... compare the leading economic history journals with the leading journals in economics in order to measure the influence on economics of economic history, and vice versa. With a few exceptions, our results confirm the general idea about what economic history journals are the most influential for economic...

  8. Recurrent fuzzy ranking methods

    Science.gov (United States)

    Hajjari, Tayebeh

    2012-11-01

    With the increasing development of fuzzy set theory in various scientific fields and the need to compare fuzzy numbers in different areas. Therefore, Ranking of fuzzy numbers plays a very important role in linguistic decision-making, engineering, business and some other fuzzy application systems. Several strategies have been proposed for ranking of fuzzy numbers. Each of these techniques has been shown to produce non-intuitive results in certain case. In this paper, we reviewed some recent ranking methods, which will be useful for the researchers who are interested in this area.

  9. Academic Training Lecture - Regular Programme

    CERN Multimedia

    PH Department

    2011-01-01

    Regular Lecture Programme 9 May 2011 ACT Lectures on Detectors - Inner Tracking Detectors by Pippa Wells (CERN) 10 May 2011 ACT Lectures on Detectors - Calorimeters (2/5) by Philippe Bloch (CERN) 11 May 2011 ACT Lectures on Detectors - Muon systems (3/5) by Kerstin Hoepfner (RWTH Aachen) 12 May 2011 ACT Lectures on Detectors - Particle Identification and Forward Detectors by Peter Krizan (University of Ljubljana and J. Stefan Institute, Ljubljana, Slovenia) 13 May 2011 ACT Lectures on Detectors - Trigger and Data Acquisition (5/5) by Dr. Brian Petersen (CERN) from 11:00 to 12:00 at CERN ( Bldg. 222-R-001 - Filtration Plant )

  10. Lectures in general algebra

    CERN Document Server

    Kurosh, A G; Stark, M; Ulam, S

    1965-01-01

    Lectures in General Algebra is a translation from the Russian and is based on lectures on specialized courses in general algebra at Moscow University. The book starts with the basics of algebra. The text briefly describes the theory of sets, binary relations, equivalence relations, partial ordering, minimum condition, and theorems equivalent to the axiom of choice. The text gives the definition of binary algebraic operation and the concepts of groups, groupoids, and semigroups. The book examines the parallelism between the theory of groups and the theory of rings; such examinations show the

  11. Twenty lectures on thermodynamics

    CERN Document Server

    Buchdahl, H A

    2013-01-01

    Twenty Lectures on Thermodynamics is a course of lectures, parts of which the author has given various times over the last few years. The book gives the readers a bird's eye view of phenomenological and statistical thermodynamics. The book covers many areas in thermodynamics such as states and transition; adiabatic isolation; irreversibility; the first, second, third and Zeroth laws of thermodynamics; entropy and entropy law; the idea of the application of thermodynamics; pseudo-states; the quantum-static al canonical and grand canonical ensembles; and semi-classical gaseous systems. The text

  12. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    26, 27, 28 February and 1, 2 March REGULAR LECTURE PROGRAMME From 11:00 hrs - Main Auditorium bldg. 500 Recent Results on CP Violation and B Physics P.F. HARRISON / QMW, London, UK With the advent of the asymmetric B factories in Japan and the US, exciting new results on CP Violation and B Physics are starting to be achieved. In these lectures, we review the existing experimental and phenomenological context of these measurements, we compare and contrast the new experimental facilities and discuss the implications of the recent results on our understanding. Finally we summarise the prospects for future developments.

  13. A Comparison of Three Major Academic Rankings for World Universities: From a Research Evaluation Perspective

    Directory of Open Access Journals (Sweden)

    Mu-hsuan Huang

    2011-06-01

    Full Text Available This paper introduces three current major university ranking systems. The Performance Ranking of Scientific Papers for World Universities by Higher Education Evaluation and Accreditation Council of Taiwan (HEEACT Ranking emphasizes both the quality and quantity of research and current research performance. The Academic Ranking of World Universities by Shanghai Jiao Tung University (ARWU focuses on outstanding performance of universities with indicators such as Nobel Prize winners. The QS World University Ranking (2004-2009 by Times Higher Education (THE-QS emphasizes on peer review with high weighting in evaluation. This paper compares the 2009 ranking results from the three ranking systems. Differences exist in the top 20 universities in three ranking systems except the Harvard University, which scored top one in all of the three rankings. Comparisons also revealed that the THE-QS favored UK universities. Further, obvious differences can be observed between THE-QS and the other two rankings when ranking results of some European countries (Germany, UK, Netherlands, & Switzerland and Chinese speaking regions were compared.

  14. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    1, 2, 3, 4 and 5 October LECTURES FOR POSTGRADUATE STUDENTS From 10:00 hrs - Main Auditorium bldg. 500 1 Introduction to particle accelerators E.J.N. Wilson / CERN-AC , Head of the CERN Accelerator School This new series of lectures is intended for anyone with a technical or scientific background who would like to become familiar with the principles of accelerator design. It is a complement to last year's course and includes new lectures on present day accelerators, and their applications as well as colliders and neutrino factories. Beam dynamics, which was treated at length in last year's course, has been compressed into one lecture, intended as revision for those who followed earlier courses and an introduction for newcomers to the field. The course should not be missed by those who will attend the CAS Intermediate Accelerator School in Seville. 1-10 10:00 Present-day Accelerators 11:00 - Beam Dynamics 2-10 10:00 Accelerating Cavities 11:00 - Non-linear Dynamics 3-10 10:00 Electron Dynamics 11:00 - ...

  15. Summer Student Lecture Programme

    CERN Multimedia

    2004-01-01

    Main Auditorium, bldg. 500 DATE TIME LECTURER TITLE Monday 2 August 09:15 - 10:00 P. Wells (CERN) The Higgs Saga at LEP 10:15 - 11:00 G. Cowan (Univ. of London) Introduction to Statistics (2/3) 11:15 - 12:00 G. Cowan (Univ. of London) Introduction to Statistics (3/3) DATE TIME LECTURER TITLE Tuesday 3 August 09:15 - 10:00 P. Sphicas (CERN) Trigger and Data Acquisition Systems (1/2) 10:15 - 11:00 R. Jacobsen (LBLN) From Raw Data to Physics Results (1/2) 11:15 - 12:00 R. Jacobsen (LBLN) G. Cowan (University of London) Discussion Session DATE TIME LECTURER TITLE Wednesday 4 August 09:15 - 10:00 P. Sphicas (CERN) Trigger and Data Acquisition Systems (2/2) 10:15 - 11:00 R. Jacobsen (LBLN) From Raw Data to Physics Results (2/2) 11:15 - 12:00 N. Palanque-Delabrouille (CEA) Astroparticle Physics (1/3) DATE TIME LECTURER TITLE Thursday 5 August 09:15 - 10:00 N. Palanque-Delabrouille (CEA) Astroparticle Physics (2/3) 10:15 - 11:00 N. Palanque-Delabrouille (CEA) A...

  16. When Lecturing: Teach!

    Science.gov (United States)

    Aiken, Warren R.

    1980-01-01

    Techniques that can be used to make the lecture method of teaching more effective include using pictures or objects to facilitate memory, using guided fantasies to stimulate students' imagination of processes, and the suggestopedia method for memorizing facts, principles, and vocabulary. (MSE)

  17. Organic Lecture Demonstrations.

    Science.gov (United States)

    Silversmith, Ernest F.

    1988-01-01

    Provides a listing of 35 demonstrations designed to generate interest in organic chemistry and help put points across. Topics include opening lecture; molecular structure and properties; halogenation; nucleophilic substitution, alkenes and dienes, stereochemistry, spectroscopy, alcohols and phenols, aldehydes and ketones; carboxylic acids, amines,…

  18. The Harvey lectures, Series 82

    Energy Technology Data Exchange (ETDEWEB)

    Botstein, D.; Cech, T.R.; Hille, B.; Lodish, H.F.; Majerus, P.W.

    1988-01-01

    The Harvey Lecture Series is published annually and provides reviews of research topics in the biomedical sciences. Eight lectures by investigators are included in the volume representing the most recent work in the major laboratories.

  19. Public Lecture: Human Space Exploration

    CERN Multimedia

    CERN. Geneva

    2015-01-01

    Should you wish to attend to this lecture only (and not the full colloquium), please register here: https://indico.cern.ch/event/386996/registration/ Participants to the full colloquium are automatically registered to the public lectures.

  20. Asset ranking manager (ranking index of components)

    Energy Technology Data Exchange (ETDEWEB)

    Maloney, S.M.; Engle, A.M.; Morgan, T.A. [Applied Reliability, Maracor Software and Engineering (United States)

    2004-07-01

    The Ranking Index of Components (RIC) is an Asset Reliability Manager (ARM), which itself is a Web Enabled front end where plant database information fields from several disparate databases are combined. That information is used to create a specific weighted number (Ranking Index) relating to that components health and risk to the site. The higher the number, the higher priority that any work associated with that component receives. ARM provides site Engineering, Maintenance and Work Control personnel with a composite real time - (current condition) look at the components 'risk of not working' to the plant. Information is extracted from the existing Computerized Maintenance management System (CMMS) and specific site applications and processed nightly. ARM helps to ensure that the most important work is placed into the workweeks and the non value added work is either deferred, frequency changed or deleted. This information is on the web, updated each night, and available for all employees to use. This effort assists the work management specialist when allocating limited resources to the most important work. The use of this tool has maximized resource usage, performing the most critical work with available resources. The ARM numbers are valued inputs into work scoping for the workweek managers. System and Component Engineers are using ARM to identify the components that are at 'risk of failure' and therefore should be placed into the appropriate work week schedule.

  1. Autophagy: one more Nobel Prize for yeast

    Directory of Open Access Journals (Sweden)

    Andreas Zimmermann

    2016-12-01

    Full Text Available The recent announcement of the 2016 Nobel Prize in Physiology or Medicine, awarded to Yoshinori Ohsumi for the discoveries of mechanisms governing autophagy, underscores the importance of intracellular degradation and recycling. At the same time, it further cements yeast, in which this field decisively developed, as a prolific model organism. Here we provide a quick historical overview that mirrors both the importance of autophagy as a conserved and essential process for cellular life and death as well as the crucial role of yeast in its mechanistic characterization.

  2. Autophagy: one more Nobel Prize for yeast.

    Science.gov (United States)

    Zimmermann, Andreas; Kainz, Katharina; Andryushkova, Aleksandra; Hofer, Sebastian; Madeo, Frank; Carmona-Gutierrez, Didac

    2016-12-05

    The recent announcement of the 2016 Nobel Prize in Physiology or Medicine, awarded to Yoshinori Ohsumi for the discoveries of mechanisms governing autophagy, underscores the importance of intracellular degradation and recycling. At the same time, it further cements yeast, in which this field decisively developed, as a prolific model organism. Here we provide a quick historical overview that mirrors both the importance of autophagy as a conserved and essential process for cellular life and death as well as the crucial role of yeast in its mechanistic characterization.

  3. Arthroscopy Journal Prizes Are Major Decisions.

    Science.gov (United States)

    Lubowitz, James H; Brand, Jefferson C; Provencher, Matthew T; Rossi, Michael J

    2016-01-01

    According to the Harvard Business Review, the optimal number of people in a decision-making group is no more than 8. Thus, it is no surprise that 18 Arthroscopy journal associate editors had difficulty making a major decision. In the end, 18 editors did successfully select the 2015 winner of the Best Comparative Study Prize. All studies have limitations, but from a statistical standpoint, the editors believe that the conclusions of the winning study are likely correct. Copyright © 2016 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.

  4. A Nobel Prize winner visits CERN

    CERN Multimedia

    2007-01-01

    Nobel Prize-winning astrophysicist George Smoot visited CERN on 2 February with a message for particle physicists and cosmologists alike. After a tour of ATLAS and CMS, Smoot gave a talk to a packed Council Chamber about the connections between particle physics and cosmology, and how the two disciplines can help each other to find answers to their cosmic questions. Smoot's group at Lawrence Berkeley National Laboratory is currently working on the development of the Max Planck Surveyor, the next generation of satellite to study cosmic microwave background anisotropy, which will teach us about how our universe was formed.

  5. Nobel prize awarded to pioneers in ozone research

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    This article details the achievements of the three individuals who shared the 1995 Nobel Prize in Chemistry - Paul Crutzen, Mario Molina, and F. Sherwood Rowland - for their work in atmospheric chemistry, particularly the chemical processes that deplete the ozone layer. Background information about the ozone layer is presented as well as highlights of the ozone research done by the prize winners.

  6. 2008 Nobel prize in Medicine for discoverers of HIV

    Directory of Open Access Journals (Sweden)

    Berkhout Ben

    2008-10-01

    Full Text Available Abstract Françoise Barré-Sinoussi and Luc Montagnier, codiscoverers of HIV, the causative agent of AIDS, have been awarded the 2008 Nobel Prize in Physiology or Medicine. They share this prize with Harald zur Hausen who was responsible for establishing the link between human papilloma virus infection and cervical carcinoma.

  7. Nominations sought for the 2016 Haagen-Smit Prize

    Science.gov (United States)

    2016-09-01

    We, the editors and publishers of Atmospheric Environment invite our readers to nominate papers for the 2016 "Haagen-Smit Prize". The prize is named in honor of Prof. Arie Jan Haagen-Smit, a pioneer in the field of air pollution.

  8. 2008 Nobel prize in Medicine for discoverers of HIV

    NARCIS (Netherlands)

    Lever, Andrew M. L.; Berkhout, Ben

    2008-01-01

    ABSTRACT: Francoise Barre-Sinoussi and Luc Montagnier, codiscoverers of HIV, the causative agent of AIDS, have been awarded the 2008 Nobel Prize in Physiology or Medicine. They share this prize with Harald zur Hausen who was responsible for establishing the link between human papilloma virus

  9. Briton wins Nobel physics prize for work on superfluids

    CERN Multimedia

    Connor, S

    2003-01-01

    A British born scientist, Anthony Leggett, 65, has jointly won this year's Nobel prize in physics for research into the arcane area of superfluids - when matter behaves in its lowest and most ordered state. He shares the 800,000 pounds prize with two Russian physicists who have worked in the field of superconductivity - when electrical conductors lose resistance (1/2 page).

  10. 26 CFR 1.74-1 - Prizes and awards.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 2 2010-04-01 2010-04-01 false Prizes and awards. 1.74-1 Section 1.74-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Items Specifically Included in Gross Income § 1.74-1 Prizes and awards. (a) Inclusion in gross income. (1) Section 74(a)...

  11. Multiplex PageRank.

    Directory of Open Access Journals (Sweden)

    Arda Halu

    Full Text Available Many complex systems can be described as multiplex networks in which the same nodes can interact with one another in different layers, thus forming a set of interacting and co-evolving networks. Examples of such multiplex systems are social networks where people are involved in different types of relationships and interact through various forms of communication media. The ranking of nodes in multiplex networks is one of the most pressing and challenging tasks that research on complex networks is currently facing. When pairs of nodes can be connected through multiple links and in multiple layers, the ranking of nodes should necessarily reflect the importance of nodes in one layer as well as their importance in other interdependent layers. In this paper, we draw on the idea of biased random walks to define the Multiplex PageRank centrality measure in which the effects of the interplay between networks on the centrality of nodes are directly taken into account. In particular, depending on the intensity of the interaction between layers, we define the Additive, Multiplicative, Combined, and Neutral versions of Multiplex PageRank, and show how each version reflects the extent to which the importance of a node in one layer affects the importance the node can gain in another layer. We discuss these measures and apply them to an online multiplex social network. Findings indicate that taking the multiplex nature of the network into account helps uncover the emergence of rankings of nodes that differ from the rankings obtained from one single layer. Results provide support in favor of the salience of multiplex centrality measures, like Multiplex PageRank, for assessing the prominence of nodes embedded in multiple interacting networks, and for shedding a new light on structural properties that would otherwise remain undetected if each of the interacting networks were analyzed in isolation.

  12. Multiplex PageRank.

    Science.gov (United States)

    Halu, Arda; Mondragón, Raúl J; Panzarasa, Pietro; Bianconi, Ginestra

    2013-01-01

    Many complex systems can be described as multiplex networks in which the same nodes can interact with one another in different layers, thus forming a set of interacting and co-evolving networks. Examples of such multiplex systems are social networks where people are involved in different types of relationships and interact through various forms of communication media. The ranking of nodes in multiplex networks is one of the most pressing and challenging tasks that research on complex networks is currently facing. When pairs of nodes can be connected through multiple links and in multiple layers, the ranking of nodes should necessarily reflect the importance of nodes in one layer as well as their importance in other interdependent layers. In this paper, we draw on the idea of biased random walks to define the Multiplex PageRank centrality measure in which the effects of the interplay between networks on the centrality of nodes are directly taken into account. In particular, depending on the intensity of the interaction between layers, we define the Additive, Multiplicative, Combined, and Neutral versions of Multiplex PageRank, and show how each version reflects the extent to which the importance of a node in one layer affects the importance the node can gain in another layer. We discuss these measures and apply them to an online multiplex social network. Findings indicate that taking the multiplex nature of the network into account helps uncover the emergence of rankings of nodes that differ from the rankings obtained from one single layer. Results provide support in favor of the salience of multiplex centrality measures, like Multiplex PageRank, for assessing the prominence of nodes embedded in multiple interacting networks, and for shedding a new light on structural properties that would otherwise remain undetected if each of the interacting networks were analyzed in isolation.

  13. Ranking of Rankings: Benchmarking Twenty-Five Higher Education Ranking Systems in Europe

    Science.gov (United States)

    Stolz, Ingo; Hendel, Darwin D.; Horn, Aaron S.

    2010-01-01

    The purpose of this study is to evaluate the ranking practices of 25 European higher education ranking systems (HERSs). Ranking practices were assessed with 14 quantitative measures derived from the Berlin Principles on Ranking of Higher Education Institutions (BPs). HERSs were then ranked according to their degree of congruence with the BPs.…

  14. George E. Pake Prize Lecture: CMOS Technology Roadmap: Is Scaling Ending?

    Science.gov (United States)

    Chen, Tze-Chiang (T. C.)

    The development of silicon technology has been based on the principle of physics and driven by the system needs. Traditionally, the system needs have been satisfied by the increase in transistor density and performance, as suggested by Moore's Law and guided by ''Dennard CMOS scaling theory''. As the silicon industry moves towards the 14nm node and beyond, three of the most important challenges facing Moore's Law and continued CMOS scaling are the growing standby power dissipation, the increasing variability in device characteristics and the ever increasing manufacturing cost. Actually, the first two factors are the embodiments of CMOS approaching atomistic and quantum-mechanical physics boundaries. Industry directions for addressing these challenges are also developing along three primary approaches: Extending silicon scaling through innovations in materials and device structure, expanding the level of integration through three-dimensional structures comprised of through-silicon-vias holes and chip stacking in order to enhance functionality and parallelism and exploring post-silicon CMOS innovation with new nano-devices based on distinctly different principles of physics, new materials and new processes such as spintronics, carbon nanotubes and nanowires. Hence, the infusion of new materials, innovative integration and novel device structures will continue to extend CMOS technology scaling for at least another decade.

  15. Earle K. Plyler Prize Lecture: The Three Pillars of Ultrafast Molecular Science - Time, Phase, Intensity

    Science.gov (United States)

    Stolow, Albert

    We discuss the probing and control of molecular wavepacket dynamics in the context of three main `pillars' of light-matter interaction: time, phase, intensity. Time: Using short, coherent laser pulses and perturbative matter-field interactions, we study molecular wavepackets with a focus on the ultrafast non-Born-Oppenheimer dynamics, that is, the coupling of electronic and nuclear motions. Time-Resolved Photoelectron Spectroscopy (TRPES) is a powerful ultrafast probe of these processes in polyatomic molecules because it is sensitive both electronic and vibrational dynamics. Ideally, one would like to observe these ultrafast processes from the molecule's point of view - the Molecular Frame - thereby avoiding loss of information due to orientational averaging. This can be achieved by Time-Resolved Coincidence Imaging Spectroscopy (TRCIS) which images 3D recoil vectors of both photofragments and photoelectrons, in coincidence and as a function of time, permitting direct Molecular Frame imaging of valence electronic dynamics during a molecular dynamics. Phase: Using intermediate strength non-perturbative interactions, we apply the second order (polarizability) Non-Resonant Dynamic Stark Effect (NRDSE) to control molecular dynamics without any net absorption of light. NRDSE is also the interaction underlying molecular alignment and applies to field-free 1D of linear molecules and field-free 3D alignment of general (asymmetric) molecules. Using laser alignment, we can transiently fix a molecule in space, yielding a more general approach to direct Molecular Frame imaging of valence electronic dynamics during a chemical reaction. Intensity: In strong (ionizing) laser fields, a new laser-matter physics emerges for polyatomic systems wherein both the single active electron picture and the adiabatic electron response, both implicit in the standard 3-step models, can fail dramatically. This has important consequences for all attosecond strong field spectroscopies of polyatomic molecules, including high harmonic generation (HHG). We discuss an experimental method, Channel-Resolved Above Threshold Ionization (CRATI), which directly unveils the electronic channels participating in the attosecond molecular strong field ionization response [10]. This work was supported by the National Research Council of Canada and the Natural Sciences & Engineering Research Council.

  16. Rahman Prize Lecture: Lattice Boltzmann simulation of complex states of flowing matter

    Science.gov (United States)

    Succi, Sauro

    Over the last three decades, the Lattice Boltzmann (LB) method has gained a prominent role in the numerical simulation of complex flows across an impressively broad range of scales, from fully-developed turbulence in real-life geometries, to multiphase flows in micro-fluidic devices, all the way down to biopolymer translocation in nanopores and lately, even quark-gluon plasmas. After a brief introduction to the main ideas behind the LB method and its historical developments, we shall present a few selected applications to complex flow problems at various scales of motion. Finally, we shall discuss prospects for extreme-scale LB simulations of outstanding problems in the physics of fluids and its interfaces with material sciences and biology, such as the modelling of fluid turbulence, the optimal design of nanoporous gold catalysts and protein folding/aggregation in crowded environments.

  17. W.K.H. Panofsky prize lecture: The taste of neutrinos

    Energy Technology Data Exchange (ETDEWEB)

    Sciulli, F.

    1995-04-01

    Experience is described from two decades of experiments using beams of high energy neutrinos at Fermi National Accelerator Laboratory. This program came about through the dedicated commitment of many talented people. The results, primarily measurements of neutrino cross-sections with nucleons, had impact on present knowledge of the structure of nucleons and QCD, the properties of the weak neutral current, as well as providing constraints on new properties for the neutrino and its interactions.

  18. Oliver E. Buckley Condensed Matter Prize Lecture: Topological insulators and superconductors

    Science.gov (United States)

    Zhang, Shoucheng

    2012-02-01

    In this talk I shall briefly review the basic concepts of topological insulators and superconductors, and recall the history of the discovery of the first topological insulator in nature, the HgTe material. I will then describe some striking physical properties of topological insulators and their possible applications. [4pt] X. L. Qi, S. C. Zhang, Phys. Today 63, 33 (2010). X. L. Qi, S. C. Zhang, Rev. Mod. Phys. 83, 1057 (2011).

  19. Robert Feulgen Prize Lecture 1995. New approaches to in situ detection of nucleic acids.

    Science.gov (United States)

    Thiry, M

    1995-08-01

    The present paper reviews recent results obtained by different molecular biology-based, immunocytological approaches to the localization and identification of nucleic acids in sections of biological material. Examples of sensitive, high-resolution detection methods for RNA, DNA or specialized DNA regions are presented. Special emphasis is placed on the potential values and limitations of these new methods.

  20. George E. Pake Prize Lecture: Crystalline Silicon Photovoltaics: Accelerating to Grid Parity

    Science.gov (United States)

    Pinto, Mark

    2013-03-01

    Lost in recent headlines about solar company failures, reduced government support and depressed stock valuations is the fact that photovoltaic (PV) systems continue to be installed at an extremely healthy rate - a ten-fold increase between 2007 and 2012, to a cumulative 100GWp of installations worldwide. The primary factor behind this remarkable growth has been cost reduction at the installed system level afforded by manufacturing and technology improvements to the crystalline silicon (c-Si) PV cell. In fact in the past 2 years, c-Si module cost learning curves have accelerated over their historical norms as a function of both volume and time, and as a result c-Si PV has reached parity with conventional forms of electricity in 20 + countries worldwide. In this presentation future c-Si technology paths will be reviewed along with market implications, leading to the projection that between 2015 and 2020, c-Si based PV electricity will be cost-effectively delivered to >95% of the world's population.

  1. From the Acta Prize Lecture 2014: the periodontal-systemic connection seen from a microbiological standpoint.

    Science.gov (United States)

    Olsen, Ingar

    2015-01-01

    To give an overview of the periodontal-systemic connection seen from a microbiologist. Original research papers, review articles and workshop proceedings were consulted. Periodontal bacteria can cross epithelial cells, enter the circulation, invade endothelial cells, induce endothelial cell dysfunction and activate inflammatory and immune responses. Several studies support the association between periodontitis (PD) and cardiovascular disease. Severe PD involves a risk for development of type 2 diabetes. Maternal PD is moderately associated with adverse pregnancy outcome and pre-eclampsia. Dental plaque can contain respiratory pathogens able to promote chronic obstructive pulmonary disease and pneumonia. Periodontal bacterial DNA has been detected in synovial fluid of patients with rheumatoid arthritis. Minor evidence exists for associations between PD and chronic kidney disease, obesity, cancer, metabolic syndrome and cognitive impairment. Concerns can be raised as to the interpretation of some study results due to heterogeneity in definitions used for PD, too much weight upon in vitro studies with a few selected organisms and failing recognition that the majority of the periodontal microbiota is not yet cultivated. Periodontal bacteria may participate in extra-oral infections such as CVD, diabetes, APO, pre-eclampsia, COPD, pneumonia, RA, CKD, obesity, cancer, MetS and cognitive impairment. Most knowledge is based on associations which do not necessarily imply causality. Future studies should reach consensus on the definition of PD and systemic disease outcomes, recognize the full spectrum of the microbiota in PD and bacteremia, including not-yet-cultivated organisms and delineate the clinical significance of genetic strain variations and the role of periodontopathogenic vs gut organisms within atheromatous lesions. For demonstration of causality, large, long-term clinical studies should use well-defined criteria for PD and robust disease outcomes to elucidate the importance of PD intervention and prevention.

  2. Otto Laporte Lecture: Fluid Dynamics Prize Talk: Simple Models for Turbulent Flows

    Science.gov (United States)

    Pope, Stephen B.

    2009-11-01

    We focus on the modeling of two turbulent flows: dispersion from a line source in grid turbulence; and, a lifted non-premixed turbulent jet flame. Stochastic Lagrangian models and PDF methods are described, and are shown to model these flows satisfactorily. For the line source, a Lagrangian approach is taken, with the Langevin equation modeling the velocity following a fluid particle, and with a simple relaxation model for the particle temperature. Comparison with experimental data shows that the resulting model describes accurately the dispersion from single and multiple line sources. These simple stochastic Lagrangian models are then applied to the much more challenging case of a lifted non-premixed jet flame. The stochastic Lagrangian models form the basis for a particle/mesh numerical method for solving a modeled transport equation for the Eulerian joint probability density function (PDF) of velocity and composition. The PDF calculations are in excellent agreement with the experimental data, and exhibit the observed extreme sensitivity of the flame to the temperature of the co-flow. The PDF model calculations presented clearly demonstrate that simple models can be very useful, even though aspects of their behavior may be inaccurate or incomplete. The shortcomings of the Langevin equation are examined, and more advanced models (designed to overcome some of these shortcomings) are described. These include models for fluid-particle acceleration, including the effects of intermittency; models accounting for mean shear, which are correct in the rapid- distortion limit; and models designed for use in conjunction with large-eddy simulations (LES).

  3. RET/PTC activation in papillary thyroid carcinoma: European Journal of Endocrinology Prize Lecture.

    Science.gov (United States)

    Santoro, Massimo; Melillo, Rosa Marina; Fusco, Alfredo

    2006-11-01

    Papillary thyroid carcinoma (PTC) is frequently associated with RET gene rearrangements that generate the so-called RET/PTC oncogenes. In this review, we examine the data about the mechanisms of thyroid cell transformation, activation of downstream signal transduction pathways and modulation of gene expression induced by RET/PTC. These findings have advanced our understanding of the processes underlying PTC formation and provide the basis for novel therapeutic approaches to this disease.

  4. The G. L. Brown Prize Lecture. Hypoxic regulation of ion channel function and expression.

    Science.gov (United States)

    Peers, Chris

    2002-07-01

    Acute hypoxia regulates the activity of specific ion channels in a rapid and reversible manner. Such effects underlie appropriate cellular responses to hypoxia which are designed to initiate cardiorespiratory reflexes and contribute importantly to other tissue responses, all of which are designed to improve tissue O2 supply. These responses include excitation of chemoreceptors as well as pulmonary vasoconstriction and systemic vasodilatation. However, such responses may also contribute to the adverse responses to hypoxia, such as excitotoxicity in the central nervous system. Whilst numerous ion channel types are known to be modulated by acute hypoxia, the nature of the O2 sensor in most tissues remains to be identified. Prolonged (chronic) hypoxia regulates functional expression of ion channels, and so remodels excitability of various cell types. Whilst this may contribute to adaptive responses such as high-altitude acclimatization, such altered channel expression may also contribute to the onset of pathological disorders, including Alzheimer's disease. Indeed, evidence is emerging that production of pathological peptides associated with Alzheimer's disease is increased during prolonged hypoxia. Such effects may account for the known increased incidence of this disease in patients who have previously endured hypoxic episodes, such as congestive heart failure and stroke. Identification of the mechanisms coupling hypoxia to the increased production of these peptides is likely to be of therapeutic benefit.

  5. Nitric oxide and the autonomic regulation of cardiac excitability. The G.L. Brown Prize Lecture.

    Science.gov (United States)

    Paterson, D

    2001-01-01

    Cardiac sympathetic imbalance and arrhythmia; Nitric oxide-cGMP pathway and the cholinergic modulation of cardiac excitability; Nitric oxide-cGMP pathway and the sympathetic modulation of cardiac excitability; Functional significance of nitric oxide in the autonomic regulation of cardiac excitability; Summary; References. Experimental Physiology (2001) 86.1, 1-12.

  6. Julius Edgar Lilienfeld Prize Lecture: Mapping the Universe: Physics Writ Large

    Science.gov (United States)

    Geller, Margaret

    2013-03-01

    The age of mapping the universe began in earnest in the late twentieth century. I will describe the enormous strides we have made in mapping the galaxy distribution and in understanding its nature and history. I will show how techniques for measuring the (primarily dark) matter distribuion in massive systems of galaxies are an astrophysical route to tests of fundamental physics.

  7. The Abraham Pais Prize Lecture: The historical Development of the Physical Concept of Time

    Science.gov (United States)

    Jammer, Max

    2007-04-01

    The Irish physicist and mathematician John Lighton Synge once (1959) proclaimed that of all physical measurements that of time is the most fundamental and its theory ``the most basic theory of all.'' Twenty years later the Belgian physicist and chemist Ilya Prigogine declared that ``the concept of time is much more complex than we thought.'' Indeed, having studied the basic notions in physics like space, mass, force, simultaneity and written on each of them a detailed monograph, I always postponed a similar treatment of the concept of time because I realized that just by being the ``most basic'' it is also the most ``complex'' of all notions in physics and therefore a rather complicated subject of research. In fact, time, as perceived by us, is both ``flowing'' and ``enduring'' and its ``passing'' always ``lasts.'' If I venture nevertheless to offer herewith a survey of the conceptual development of the notion of time, I do so because I delimit myself to the role of time only in physics and ignore as far as possible general metaphysical, psychological or biological issues. The presentation thus ignores the history of the notion of time as conceived in the myths and religions of ancient civilizations and begins, after some brief remarks about the Pythagoreans, with the theories of time as proposed by the Pre-Socratics, Plato and Aristotle. After a critical discourse on the early proponents of an idealistic interpretation of the notion of time, like that of St. Augustine, medieval theories of time, like those which proposed the atomicity of time, are discussed. After a presentation of sixteenth century discussions of time, like that by Bruno or Gassendi, Isaac Barrow's and Isaac Newton's theories of physical time are critically analyzed. This is followed by a brief study of the conceptions of time by Locke and Berkeley and subsequently by Leibniz, who is often regarded as the first proponent of a relational or causal theory of time. Following some brief remarks about Hume's conception of time Kant's critical investigation of the notion of time is analyzed and followed by the theories of an ``arrow if time'' as a result of the existence of irreversible thermodynamic processes. After a brief discussion of Poincar'e's thesis of the conventional status of temporal metric, Einstein's interpretation of distant simultaneity and consequently his definition of time via simultaneity, as presented in his famous 1905 paper on relativity, are discussed. This is followed by some remarks on the concept of time in the general theory of relativity. A brief outline of the role of the concept of time in modern cosmology and, in particular, Hawking's notion of ``imaginary time'' conclude this essay.

  8. Polymer Physics Prize Lecture: Polyelectrolyte complexes: New routes to useful soft materials

    Science.gov (United States)

    Tirrell, Matthew

    2012-02-01

    Mixtures of oppositely charged polyelectrolytes may form precipitates (phase-separated solids) or coacervates (phase-separated fluids). Coacervates have been known for a long time to have interesting properties such as very low interfacial tension with water and a resultant ability to coat surfaces, engulf particles and invade porous media. Most prior work on coacervate complexes has been done with structurally complex (e.g., gum Arabic), biologically derived macromolecules (e.g., gelation). Our work is focusing on phase behavior and self-assembly in classes of structurally simpler polymers. Polypeptides are one such class, where we can produce anionic, cationic and neutral, water-soluble polymers all with the some backbone and varying in small side-group structures. We are able to demonstrate very general patterns in phase behavior over different members of this class of polymers. Coacervate formation is the rule rather than the exception in these materials, with such formation quite strongly peaked at balanced stoichiometry of the polyelectrolyte components. One molar salt is usually sufficient to dissolve the coacervate phases that form. Block copolymer mixtures containing oppositely charged blocks can form self-assembled structures: micelles with diblocks and hydrogels with triblocks. The structure and properties of these assemblies can be tuned based on knowledge of the bulk phase behavior response to molecular weight, stoichiometry and salt concentration. Examples of phase behavior and structure-property relationship will be discussed.

  9. Nobel Lecture: From the Big Bang to the Nobel Prize and beyond

    Science.gov (United States)

    Mather, John C.

    NASA’s Cosmic Background Explorer satellite mission, the COBE, laid the foundations for modern cosmology by measuring the spectrum and anisotropy of the cosmic microwave background radiation and discovering the cosmic infrared background radiation. I describe the history of the COBE project, its scientific context, the people who built it, and the scientific results. The COBE observed the universe on the largest scales possible by mapping the cosmic microwave and infrared background radiation fields and determining their spectra. It produced conclusive evidence that the hot Big Bang theory of the early universe is correct, showed that the early universe was very uniform but not perfectly so, and that the total luminosity of post Big Bang objects is twice as great as previously believed. The COBE concept was developed by a Mission Definition Study Team appointed by NASA in 1976, based on three competing proposals submitted in 1974. The COBE was built in-house by Goddard Space Flight Center, with a helium cryostat provided by Ball Aerospace, and was launched on a Delta rocket built by McDonnell Douglas. It is in a circular orbit 900km above the Earth, in a plane inclined 99° to the equator and roughly perpendicular to the line to the Sun. It carried three instruments, a far infrared absolute spectrophotometer (FIRAS), a differential microwave radiometer with three channels (DMR), and a diffuse infrared background experiment (DIRBE). The helium cryostat cooled the FIRAS and DIRBE for 10months until the helium was exhausted, but operations continued for a total of 4years . Subsequent observations have confirmed the COBE results and led to measurements of the main cosmological parameters with a precision of a few percent.

  10. Andreas Acrivos Dissertation Prize Lecture: Stability of inviscid flows from bifurcation diagrams exploiting a variational argument

    Science.gov (United States)

    Luzzatto-Fegiz, Paolo

    2011-11-01

    Steady fluid solutions play a special role in the dynamics of a flow: stable states may be realized in practice, while unstable ones may act as attractors. Unfortunately, determining stability is often a process far more laborious than finding steady states; indeed, even for simple vortex or wave flows, stability properties have often been the subject of debate. We consider here a stability idea originating with Lord Kelvin (1876), which involves using the second variation of the energy, δ2 E , to establish bounds on a perturbation. However, for numerically obtained flows, computing δ2 E explicitly is often not feasible. To circumvent this issue, Saffman & Szeto (1980) proposed an argument linking changes in δ2 E to turning points in a bifurcation diagram, for families of steady flows. Later work has shown that this argument is unreliable; the two key issues are associated with the absence of a formal turning-point theory, and with the inability to detect bifurcations (Dritschel 1995, and references therein). In this work, we build on ideas from bifurcation theory, and link turning points in a velocity-impulse diagram to changes in δ2 E ; in addition, this diagram delivers the direction of the change of δ2 E , thereby providing information as to whether stability is gained or lost. To detect hidden solution branches, we introduce to these fluid problems concepts from imperfection theory. The resulting approach, involving ``imperfect velocity-impulse'' diagrams, leads us to new and surprising results for a wide range of fundamental vortex and wave flows; we mention here the calculation of the first steady vortices without any symmetry, and the uncovering of the complete solution structure for vortex pairs. In addition, we find precise agreement with available results from linear stability analysis. Doctoral work advised by C.H.K. Williamson at Cornell University.

  11. Walker Prize Lecture, 1977. Choriocarcinoma: can we afford to cure cancer.

    Science.gov (United States)

    Bagshawe, K. D.

    1978-01-01

    The way the management of patients with trophoblastic tumours has depended on the acquisition of new knowledge and new drugs is demonstrated. Emphasis is put on the ability to detect early disease by biochemical markers and on the ability to define on a multifactorial basis the resistance potential of the tumours. This provides a basis for stratification of treatment and the use of prophylactic chemotherapy to prevent cerebral metastases in certain patients. Although chemotherapy is often intensive and prolonged, there has so far been little evidence of long-term effects and many women have had normal pregnancies subsequently, but the limitations of present data are discussed. The difficulties of matching available resources to society's needs in the cancer field make it necessary to consider whether such treatment is unjustifiably expensive. It is shown that for these tumours early diagnosis not only proves effective in therapeutic terms but provides substantial financial savings. It is suggested that screening programmes for cancer cannot be accepted or rejected on principle. In judging them on their individual merits it is appropriate to anticipate interaction between earlier diagnosis and more effective drug treatment. PMID:626471

  12. [Commemorative lecture of receiving Imamura Memorial Prize. I. Studies on bacteriological diagnostic methods for mycobacteria].

    Science.gov (United States)

    Abe, C

    1994-08-01

    Two systems, radiometric BACTEC and biphasic MB-Check, based on liquid media proved to be significantly better than the egg-based solid media for the isolation of mycobacteria from clinical specimens. The difference in the rates of isolation of mycobacteria between two groups of media was more remarkable with smear-negative specimens. The time to the detection of the Mycobacterium tuberculosis complex with MB- Check was shorter than that with the 3% Ogawa egg method but longer than that with BACTEC. The polymerase chain reaction (PCR) using oligonucleotides based on the repetitive sequence (IS986) of M. tuberculosis as a primer and the Gen-Probe Amplified Mycobacterium Tuberculosis Direct Test (MTD), which combines an M. tuberculosis rRNA amplification method with the hybridization protection assay format, were evaluated for detection of M. tuberculosis in clinical samples. Although the sensitivities of the PCR and MTD appeared to be similar to that of culture with the MB-Check system, the two methods based on nucleic acid amplification should be very useful for rapid detection of M. tuberculosis infections without the long time required for culture of M. tuberculosis. Epidemiological studies with techniques which allow differentiation of strains within M. tuberculosis groups are important for limiting the dissemination of the disease. We analyzed six groups of small outbreaks of M. tuberculosis infections by restriction fragment length polymorphism (RFLP) analysis. Five showed identical fingerprints within each group, but one which as also suspected to have a common source of infection showed different banding patterns, emphasizing that RFLP analysis using IS986 as a probe is useful in epidemiological studies of tuberculosis.(ABSTRACT TRUNCATED AT 250 WORDS)

  13. Herbert P. Broida Prize Lecture: Probing chemical dynamics with negative ion photodetachment

    Science.gov (United States)

    Neumark, Daniel

    2013-03-01

    Photoelectron spectroscopy and its variants have been used in our laboratory to study diverse phenomena in chemical dynamics, including transition state spectroscopy, the electronic and vibrational spectroscopy of clusters, the photodissociation of reactive free radicals, hydrated electron dynamics in clusters and liquid jets, and the ultrafast dynamics of helium nanodroplets. This talk will focus on two examples of this type of work: slow electron velocity map imaging (SEVI) of trapped and cooled negative ions, and time-resolved photoelectron spectroscopy (TRPES) of negative ions. SEVI of cold ions represents a powerful means of performing high resolution photoelectron spectroscopy on complex species. Time-resolved radiation chemistry in nucleobases will be carried out with TRPES. In this work, starting with iodide-nucleobase complexes, we inject electrons into low-lying unoccupied orbitals of the nucleobase and follow the ensuing dynamics.

  14. Robert Feulgen Prize Lecture. Grenzgänger: adult bone marrow cells populate the brain.

    Science.gov (United States)

    Priller, Josef

    2003-08-01

    While the brain has traditionally been considered a rather secluded site, recent studies suggest that adult bone marrow (BM)-derived stem cells can generate glia and neurons in rodents and humans. Macrophages and microglia are the first to appear in the murine brain after transplantation of genetically marked BM cells. Within weeks after transplantation, some authors have found astrocytes and cells expressing neuronal antigens. We detected cerebellar Purkinje neurons and interneurons, such as basket cells, expressing the green fluorescent protein (GFP) 10-15 months after transplantation of GFP-labeled BM cells. The results push the boundaries of our classic view of lineage restriction.

  15. The secretory membrane system studied in real-time. Robert Feulgen Prize Lecture, 2001.

    Science.gov (United States)

    Lippincott-Schwartz, J

    2001-08-01

    The discovery and development of green fluorescent protein (GFP) from the jellyfish, Aequorea victoria, has revolutionized studies on protein localization and dynamics by allowing direct observation of a protein's life history and pathway in living cells, previously only deduced from genetic, biochemical, or immunolabeling studies. Applied to the secretory membrane system, which regulates delivery of newly synthesized proteins and lipids to the cell surface, GFP-based studies are providing important new insights into the maintenance and biogenesis of organelles, as well as the origin, pathway, and fate of secretory transport intermediates.

  16. Urey Prize Lecture: Orbital Dynamics of Extrasolar Planets, Large and Small

    Science.gov (United States)

    Ford, Eric B.

    2012-10-01

    For centuries, planet formation theories were fine tuned to explain the details of solar system. Since 1999, the Doppler technique has discovered dozens of multiple planet systems. The diversity of architectures of systems with giant planets challenged previous theories and led to insights into planet formation, orbital migration and the excitation of orbital eccentricities and inclinations. Recently, NASA's Kepler mission has identified over 300 systems with multiple transiting planet candidates, including many potentially rocky planets. Precise measurements of the orbital period and phase constrain the significance of mutual gravitational interactions and potential orbital resonances. For systems that are tightly-packed or near an orbital resonance, measurements of transit timing variations provide a new means for confirming transiting planets and detecting non-transiting planets in multiple planet systems, even around faint target stars. Over the course of the extended mission, Kepler is poised to measure the gravitational effects of mutual planetary perturbations for 200 planets, providing precise (but complex) constraints on planetary masses, densities and orbits. I will survey the systems with multiple transiting planet candidates identified by Kepler and discuss early efforts to translate these observations into new constraints on the formation and orbital evolution of planetary systems with low-mass planets.

  17. Kuiper Prize Lecture - Present and past climates of the terrestrial planets

    Science.gov (United States)

    Pollack, James B.

    1991-01-01

    An evaluation is undertaken of the current understanding of factors shaping the current climates of Venus, Mars, and the earth, in conjunction with the ways in which these planetary climates may have been different in the past. Attention is given to modeling approaches of various levels of sophistication which both characterize current climates and elucidate prior climatic epochs; these are assessed in light of observational data in order to judge degrees of success thus far and formulate major remaining questions for future investigations. Venus is noted to offer excellent opportunities for modeling the greenhouse effect.

  18. Heinrich Wieland--prize lecture. Transport of proteins across mitochondrial membranes.

    Science.gov (United States)

    Neupert, W

    1994-03-01

    The vast majority of proteins comprising the mitochondrion are encoded by nuclear genes, synthesized on ribosomes in the cytosol, and translocated into the various mitochondrial subcompartments. During this process proteins must cross the lipid membranes of the mitochondrion without interfering with the integrity or functions of the organelle. In recent years an approach combining biochemical, molecular, genetic, and morphological methodology has provided insights into various aspects of this complex process of intracellular protein sorting. In particular, a greater understanding of the molecular specificity and mechanism of targeting of mitochondrial preproteins has been reached, as a protein complex of the outer membrane which facilitates recognition and initial membrane insertion has been identified and characterized. Furthermore, pathways and components involved in the translocation of pre-proteins across the two mitochondrial membranes are being dissected and defined. The energetics of translocation and the processes of unfolding and folding of proteins during transmembrane transfer are closely linked to the function of a host of proteins known as heat-shock proteins or molecular chaperones, present both outside and inside the mitochondrion. In addition, the analysis of the process of folding of polypeptides in the mitochondrial matrix has allowed novel and unexpected insights into general pathways of protein folding assisted by folding factors. Pathways of sorting of proteins to the four different mitochondrial subcompartments--the outer membrane (OM), intermembrane space, inner membrane (IM) and matrix--are only partly understood and reveal an amazing complexity and variation. Many additional protein factors are involved in these latter processes, a few of which have been analyzed, such as cytochrome c heme lyase and cytochrome c1 heme lyase, enzymes that catalyze the covalent addition of the heme group to cytochrome c and c1 preproteins, and the mitochondrial processing peptidase which cleaves signal sequences after import of preproteins into the matrix. Thus, the study of transport of polypeptides through the mitochondrial membranes does not only contribute to the understanding of how biological membranes facilitate the penetration of macromolecules but also provides novel insights into the structure and function of this organelle.

  19. Fluid Dynamics Prize Lecture: Homogeneous Dynamos in Planets and in the Laboratory

    Science.gov (United States)

    Busse, F. H.

    2000-11-01

    Numerical simulations of the dynamo problem of the generation of magnetic fields by convection flows in rotating spherical fluid shells have been extended to a sufficiently large parameter regime such that extrapolation to the condition of planetary cores have become feasible. Besides dipolar fields, hemispherical and quadrupolar fields are preferred in various regimes of the parameter space. In the latter two cases oscillating time dependances are always found inspite of the chaotic nature of the dynamos. Subcritical dynamo states are typical and multiple dynamo states are possible. On the experimental side the homogeneous dynamo process has recently been demonstrated without the use of ferromagnetic material in Riga and Karlsruhe. Further experiments at other laboratories are expected to realize dynamos under conditions of strong turbulence.

  20. J. J. Sakurai Prize for Theoretical Particle Physics Lecture: Particle physics after the first LHC results

    Science.gov (United States)

    Altarelli, Guido

    2012-03-01

    The LHC results released so far have very much restricted the possible range for the Standard Model Higgs boson mass. Moreover some indications for a signal at a mass around 125 GeV have been found. At the same time, no clear evidence for new physics has emerged from the LHC data. We discuss the impact of these results on our understanding of particle physics. The presently allowed window for the Higgs mass and the negative results for exotic particles are compatible with both the Standard model and its Supersymmetric extensions but imply considerable restrictions and need a substantial amount of fine tuning in all cases. We discuss the options that remain open and the perspectives for the near future.

  1. What's the host and what's the microbe? The Marjory Stephenson Prize Lecture 2015.

    Science.gov (United States)

    Weiss, Robin A

    2015-09-01

    The interchange between retroviruses and their hosts is an intimate one because retroviruses integrate proviral DNA into host chromosomal DNA as an obligate step in the replication cycle. This has resulted in the occasional transduction of host genes into retroviral genomes as oncogenes, and also led to the integration of viral genomes into the host germ line that gives rise to endogenous retroviruses. I shall reflect on the evolutionary consequences of these events for virus and host. Then, I shall discuss the emergence of non-viral infections of host origin, namely, how malignant cells can give rise to eukaryotic single cell 'parasites' that colonize new hosts and how these in turn have been colonized by host mitochondria.

  2. The Wellcome Prize Lecture. Visual signals in the retina: from photons to synapses.

    Science.gov (United States)

    Lagnado, L

    2000-01-01

    The ability to see the world around us is an immediate and striking example of the abilities of the nervous system, and perhaps for this reason, vision is one of the most intensively studied aspects of brain function (Hubel, 1995). This paper examines some of the earliest steps in vision occurring in the retina (Dowling, 1987; Rodieck, 1998).

  3. EPS Prize Lecture. Licking and liking: the assessment of hedonic responses in rodents.

    Science.gov (United States)

    Dwyer, Dominic M

    2012-01-01

    Affective processes are a key determinant of behaviour: At its simplest, liked stimuli are approached while disliked stimuli are avoided. Although assessing hedonic responses in nonverbal animals can be difficult, one relatively tractable approach relies on detailed analyses of rodents' consummatory behaviour. Rodents typically produce rhythmic sets of licks that can be grouped into clusters on the basis of the intervals between licks. The mean number of licks in a cluster (cluster size) is directly related to the concentration of palatable and unpalatable solutions. These relationships suggest that lick cluster size might be a useful index of an animal's hedonic reaction to the solution being consumed. I begin by reviewing studies of conditioned flavour preference and aversion that support the idea that lick cluster size can provide useful information about rats' hedonic reactions. I then describe how this methodology has been used to address previously intractable issues in the investigation of contrast effects as well as revealing an analogue of effort justification effects that, in humans, are commonly explained in terms of cognitive dissonance reduction. Finally, I consider how lick analysis might provide information about hedonic responses in animal models of human psychiatric disorders. In all these cases, how an animal did something was particularly informative about why it was doing it.

  4. Osterbrock Prize Lecture: The Coming to Be of the Biographical Encyclopedia of Astronomers

    Science.gov (United States)

    Hockey, Thomas A.

    2017-01-01

    The four-volume Biographical Encyclopedia of Astronomers (and cosmologists), second edition, is one of a kind: There is no discipline-specific counterpart in the physical or biological sciences. The BEA is the work of 430 authors, translators, and editors who produced biographies of approximately 1,800 persons, from the beginning of history to the beginning of the era of Big Science. How did this happen? The Editor-in-chief will give a “behind the pages” view of the construction of this first-look, first-reached-from-the-shelf reference work.

  5. Tom W. Bonner Prize in Nuclear Physics Lecture: The limits of nuclear landscape

    Science.gov (United States)

    Nazarewicz, Witold

    2012-03-01

    Understanding nuclei is a quantum many-body problem of incredible richness and diversity and studies of nuclei address some of the great challenges that are common throughout modern science. Nuclear structure research strives to build a unified and comprehensive microscopic framework in which bulk nuclear properties, nuclear excitations, and nuclear reactions can all be described. A new and exciting focus in this endeavor lies in the description of exotic and short-lived nuclei at the limits of proton-to-neutron asymmetry, mass, and angular momentum. In this talk, advances in the nuclear density functional theory will be reviewed in the context of the main scientific questions, experimental developments, and the advent of extreme-scale computing platforms.

  6. Max Delbruck Prize in Biological Physics Lecture: Single-molecule protein folding and transition paths

    Science.gov (United States)

    Eaton, William

    2012-02-01

    The transition path is the tiny fraction of an equilibrium molecular trajectory when a transition occurs by crossing the free energy barrier between two states. It is a uniquely single-molecule property, and has not yet been observed experimentally for any system in the condensed phase. The importance of the transition path in protein folding is that it contains all of the mechanistic information on how a protein folds. As a major step toward observing transition paths, we have determined the average transition-path time for a fast and a slow-folding protein from a photon-by-photon analysis of fluorescence trajectories in single-molecule FRET experiments. While the folding rate coefficients differ by 10,000-fold, surprisingly, the transition-path times differ by less than 5-fold, showing that a successful barrier crossing event takes almost the same time for a fast- and a slow-folding protein, i.e. almost the same time to fold when it actually happens.

  7. James C. McGroddy Prize for New Materials Lecture: Transformation optics shapes metamaterials

    Science.gov (United States)

    Pendry, John

    2013-03-01

    Metamaterials offer a huge range of new electromagnetic properties: negative refraction, spatial inhomogeneity to name only two. To exploit the possibilities offered in this new world we need a new design tool. Maxwell's equations are exact at the classical level but lack transparency; Snell's law is elegantly visual, an aid to the imagination, but fails to account for many vital aspects of electromagnetism. Transformation optics retains an intuitive appeal, replacing the rays of Snell's law with the field lines of Maxwell whose equations is represents exactly.

  8. Harvey Prize Lecture: The calm before the storm: the link between quiescent cavities and CMEs

    Science.gov (United States)

    Gibson, S. E.

    2005-05-01

    Coronal mass ejections (CMEs) are thought to be driven by magnetic energy, stored in twisted or sheared magnetic fields. Magnetic clouds, which are interplanetary manifestations of CMEs, are commonly modeled as flux ropes of twisted magnetic field. It has also become quite standard to model the erupting CME as a flux rope. However, the question of whether the flux rope is formed during the eruption, or whether the flux rope existed prior to the eruption, remains controversial. CMEs often possess a three-part morphology in white light observations of a bright front, followed by a relatively dark cavity, and lastly a bright core associated with an erupting prominence. The three-part structure of CMEs has been shown in a variety of models to be a consequence of a magnetic flux rope topology. The same physical reasons for the presence of the cavity system in eruption hold true in quiescence, and so it is significant that the three-part structure, in the form of helmet-streamer/cavity/prominence-core often exists quiescently in the corona. I will present an analysis of a few case studies of white light quiescent cavities as observed by the HAO Mauna Loa Solar Observatory Mk4 coronagraph. In particular I will consider the 3D structure and evolution of these cavities, and how these are related to CMEs. Finally, I will discuss the implications that these observations may have for the state of the corona just prior to a CME, and more generally for the nature of coronal MHD equilibria.

  9. Julius Edgar Lilienfeld Prize Lecture: The Higgs Boson, String Theory, and the Real World

    Science.gov (United States)

    Kane, Gordon

    2012-03-01

    In this talk I'll describe how string theory is exciting because it can address most, perhaps all, of the questions we hope to understand about our world: why quarks and leptons make up our world, what forces form our world, cosmology, parity violation, and much more. I'll explain why string theory is testable in basically the same ways as the rest of physics, and why much of what is written about that is misleading. String theory is already or soon being tested in several ways, including correctly predicting the recently observed Higgs boson properties and mass, and predictions for dark matter, LHC physics, cosmological history, and more, from work in the increasingly active subfield ``string phenomenology.''

  10. Polymer Prize Lecture: A molecular perspective on the deformation of polymer glasses

    Science.gov (United States)

    Ediger, Mark

    2015-03-01

    The mechanical properties of polymer glasses, including yield and plastic flow, are important for many applications. In contrast to the flow of polymer melts, plastic flow is poorly understood at a fundamental level. One reason for this is that the deformation of polymer glasses typically occurs in a highly nonlinear regime, e.g., doubling the strain rate has little impact on the flow stress. Eyring proposed that stress increases the rate of molecular rearrangements in solids and this is the source of nonlinearity in many models. Our group has developed an optical technique to measure molecular mobility and shown that mobility during deformation can increase by more than a factor of 1000. In this talk, I will highlight recent progress including understanding the role of deformation temperature and a comparison between molecular and mechanical relaxation times. Results from recent computer simulations and molecular theories will be discussed. Finally, some comments will be made on the deformation of polymer glasses in comparison to colloidal and metallic glasses.

  11. Twenty Years of Ablative Photodecomposition (Industrial Applications of Physics Prize Lecture)

    Science.gov (United States)

    Srinivasan, Rangaswamy

    2004-03-01

    It was a little over twenty years ago that two groups, one in the U.S. and another in Hull, U.K. working independently, reported that ultraviolet laser pulses of nanosecond duration were capable of etching organic polymer films without any need for further development.In 1982, our group at the IBM Research Center which studied this phenomenon at 193nm named the process "Ablative Photodecomposition". Dyer and his group in Hull reported similar results at 248nm and 308nm in 1983. We also showed that the process worked well in the etching of tissue and had the potential to be of use in surgery since there was no detectable heat damage around the exposed area. These reports led to a burst of activity from numerous groups all over the world which has not slowed down significantly to the present day. The driving force behind the activity was and continues to be the potential for applications in several areas of computer hardware technology as well as in corneal refractive surgery. Today these applications can be said to be firmly in place and well-accepted. Strangely, the science behind the process is still a subject for serious discussion. The reason for this is the mix of physicists, chemists, medical doctors and engineers who have stepped into the debate. The result is a true 'Babel' which will be pointed out.

  12. Robert Feulgen Prize Lecture. Laser tweezers and multiphoton microscopes in life sciences.

    Science.gov (United States)

    König, K

    2000-08-01

    Near infrared (NIR) laser microscopy enables optical micromanipulation, piconewton force determination, and sensitive fluorescence studies by laser tweezers. Otherwise, fluorescence images with high spatial and temporal resolution of living cells and tissues can be obtained via non-resonant fluorophore excitation with multiphoton NIR laser scanning microscopes. Furthermore, NIR femtosecond laser pulses at TW/cm2 intensities can be used to realize non-invasive contact-free surgery of nanometer-sized structures within living cells and tissues. Applications of these novel versatile NIR laser-based tools for the determination of motility forces, coenzyme and chlorophyll imaging, three-dimensional multigene detection, non-invasive optical sectioning of tissues ("optical biopsy"), functional protein imaging, and nanosurgery of chromosomes are described.

  13. Robert Feulgen Prize Lecture 1995. Electronic light microscopy: present capabilities and future prospects.

    Science.gov (United States)

    Shotton, D M

    1995-08-01

    Electronic light microscopy involves the combination of microscopic techniques with electronic imaging and digital image processing, resulting in dramatic improvements in image quality and ease of quantitative analysis. In this review, after a brief definition of digital images and a discussion of the sampling requirements for the accurate digital recording of optical images, I discuss the three most important imaging modalities in electronic light microscopy--video-enhanced contrast microscopy, digital fluorescence microscopy and confocal scanning microscopy--considering their capabilities, their applications, and recent developments that will increase their potential. Video-enhanced contrast microscopy permits the clear visualisation and real-time dynamic recording of minute objects such as microtubules, vesicles and colloidal gold particles, an order of magnitude smaller than the resolution limit of the light microscope. It has revolutionised the study of cellular motility, and permits the quantitative tracking of organelles and gold-labelled membrane bound proteins. In combination with the technique of optical trapping (optical tweezers), it permits exquisitely sensitive force and distance measurements to be made on motor proteins. Digital fluorescence microscopy enables low-light-level imaging of fluorescently labelled specimens. Recent progress has involved improvements in cameras, fluorescent probes and fluorescent filter sets, particularly multiple bandpass dichroic mirrors, and developments in multiparameter imaging, which is becoming particularly important for in situ hybridisation studies and automated image cytometry, fluorescence ratio imaging, and time-resolved fluorescence. As software improves and small computers become more powerful, computational techniques for out-of-focus blur deconvolution and image restoration are becoming increasingly important. Confocal microscopy permits convenient, high-resolution, non-invasive, blur-free optical sectioning and 3D image acquisition, but suffers from a number of limitations. I discuss advances in confocal techniques that address the problems of temporal resolution, spherical and chromatic aberration, wavelength flexibility and cross-talk between fluorescent channels, and describe new optics to enhance axial resolution and the use of two-photon excitation to reduce photobleaching. Finally, I consider the desirability of establishing a digital image database, the BioImage database, which would permit the archival storage of, and public Internet access to, multidimensional image data from all forms of biological microscopy. Submission of images to the BioImage database would be made in coordination with the scientific publication of research results based upon these data.(ABSTRACT TRUNCATED AT 400 WORDS)

  14. George E. Pake Prize Lecture: Pulsed Laser Deposition and the Oxide Electronics Revolution

    Science.gov (United States)

    Venkatesan, T.

    2012-02-01

    The discovery of the Pulsed Laser Deposition (PLD) Process at Bellcore was followed by a stream of advances in the epitaxial growth of oxides and a variety of heterostructures and interfaces. Today Oxide Electronics is a fascinating field with a great deal of new Science and potential for applications. Following a discussion of these events, my talk will focus on the adventure involved in creating a new company, Neocera, and, at the same time, pushing ahead in the evolving field of oxide electronics. There, electron spin, pairing, and alignment to create superconductivity and magnetism have opened up new frontiers for research and materials development.

  15. The Wellcome Prize Lecture. Genetic imprinting: the battle of the sexes rages on.

    Science.gov (United States)

    Reik, W

    1996-03-01

    Genomic imprinting in mammals is an important genetic mechanism by which genes are expressed or repressed depending on which parent they have been inherited from. Some properties of the imprinting mechanism are already established; notably, some of the effects of imprinting on mammalian development can be explained by the phenotypic effects of a number of specific imprinted genes, which include major fetal growth factors. An evolutionary explanation of imprinting has also been suggested. Some of the molecular mechanisms of imprinting are known, and these include the modification of DNA and chromosomes in the form of DNA methylation and possibly heritable chromatin structures. Loss of imprinting or altered imprinting is implicated in a large number of genetic diseases and cancers. Many important issues remain to be resolved; these include the precise molecular mechanisms and, in particular, the nature of the primary imprints that are inherited from the parental gametes, and the genes that control the imprinting process. Isolation of the majority of imprinted genes and the elucidation of their phenotypic effects and physiology are major goals for the future. These studies will provide important insights into human genetics, and will connect evolutionary understanding with physiology, genetic disease and human behaviour.

  16. Prize for Industrial Applications of Physics Lecture: A physicist in Business

    Science.gov (United States)

    Woollam, John

    2013-03-01

    In the 1980s I inherited a famous ellipsometry laboratory. To speed up data acquisition and analysis I associated myself with creative scientists and engineers. We started a company which grew. Together we rapidly improved acquisition speed, accuracy, precision, spectral range, and types of applications. Yet, a business is much more than technology. In this talk I outline how a high-tech business functions, and illustrate the role of physicists and engineers in making a company successful. It is fast-paced, exciting, and enormously gratifying to provide quality instruments for researchers and industry.

  17. [Commemorative lecture of receiving Imamura Memorial Prize. Studies on prevention and treatment of childhood tuberculosis].

    Science.gov (United States)

    Takamatsu, I

    1999-11-01

    We performed a retrospective analysis of 394 patients who were treated for active tuberculosis (TB) at our hospital from 1976 to 1997. We had started early BCG vaccination campaign in Osaka Prefecture from 1995 and the coverage of BCG vaccination in infants rose up to about 90%. From that experience, we studied the current situations and measures on prevention and treatment of childhood tuberculosis. Pulmonary TB in children is successfully treated with 6-month standard short-course chemotherapy using isoniazid, rifampin, and pyrazinamide daily for 2 months, followed by isoniazid and rifampin daily for 4 months. Prognosis of childhood tuberculous meningitis (TBM) is poor, early diagnosis and prevention of TBM is important. In order to promote TB control and eliminate childhood TB, especially in infants, the following is necessary; 1) early detection and treatment of adult TB patients, source of infection, 2) prompt and appropriate contact examination and chemoprophylaxis, 3) BCG vaccination during early infancy, 4) protection from MDR-TB are most important.

  18. Wilson Prize Lecture: The Novosibirsk Tau/Charm Factory Project: prospect/status

    Science.gov (United States)

    Skrinsky, Alexander

    2002-04-01

    For a long time at the Budker Institute of Nuclear Physics, we develop step-by-step our electron-electron and electron-positron colliders. Now, the VEPP-4M collider (total energy up to 11 GeV), with a special emphasis on Two-Photon hadron physics, is in operation. The new VEPP-2000 collider, as direct extension of our VEPP-2M collider (which finished its very productive life in 2000) to the energy up to 2 GeV total, should start its commissioning phase in 2002. But our main goal in the field (for quite a few years already) is development and construction of Tau/Charm Factory (VEPP-5 collider). There are 3 main modes of operation foreseen: Maximal luminosity - up to 1 \\cdot 10^34 cm-2 sec-1. For reaching of this ambitious goal we intend to use ``round beam'' approach. The approach will be used and studied at VEPP-2000. Longitudinally polarized collisions (proposed and proved theoretically in Novosibirsk still in 1969) with luminosity 1 \\cdot 10^33 cm-2 sec-1. High monochromaticity option (down to few 10 of keV). Now the new injector complex, which would produce intense low emittance bunches of positrons and electrons (for VEPP-5, VEPP-4M and VEPP-2000 efficient operation) is nearing completion. Fraction of the VEPP-5 tunnel is constructed. We hope, when the VEPP-5 collider would become closer to completion, to attract international collaborators to use unique features of our Tau/Charm Factory.

  19. George E. Pake Prize Lecture: Physical Sciences Research at IBM: Still at the Cutting Edge

    Science.gov (United States)

    Theis, Thomas

    2015-03-01

    The information technology revolution is in its ``build out'' phase. The foundational scientific insights and hardware inventions are now many decades old. The microelectronics industry is maturing. An increasing fraction of the total research investment is in software and services, as applications of information technology transform every business and every sector of the public and private economy. Yet IBM Research continues to make substantial investments in hardware technology and the underlying physical sciences. While some of this investment is aimed at extending the established transistor technology, an increasing fraction is aimed at longer-term and possibly disruptive research - new devices for computing, such as tunneling field-effect transistors and nanophotonic circuits, and new architectures, such as neurosynaptic systems and quantum computing. This research investment is a bet that the old foundations of information technology are ripe for reinvention. After all, today's information technology devices and systems operate far from any fundamental limits on speed and energy efficiency. But how can IBM make risky long-term research investments in an era of global competition, with financial markets focused on the short term? One important answer is partnerships. Since its early days, IBM Research has pursued innovation in information technology and innovation in the ways it conducts the business of research. By continuously evolving new models for research and development partnerships, it has extended its global reach, increased its impact on IBM's customers, and expanded the breadth and depth of its research project portfolio. Research in the physical sciences has often led the way. Currently on assignment to the Semiconductor Research Corporation.

  20. Bok Prize Lecture (shared) Towards a Physical Characterization of Extrasolar Planets

    Science.gov (United States)

    Seager, Sara

    2004-03-01

    We have entered a new era in planetary astrophysics with well over 100 giant planets now known to orbit nearby sun-like stars. Recent theoretical and observational advances have given us new constraints on the physical characteristics of extrasolar planets, while ongoing and proposed observing programs and space missions hold great promise for the future of extrasolar planet science. I will discuss the emerging understanding of the extrasolar transiting planet HD209458b, tying together several recent observational constraints as well as key upcoming measurements.I will also briefly review scientific highlights and prospects for the future detection and study of Earth-like extrasolar planets.

  1. X-ray astronomy in the Uhuru epoch and beyond /Newton Lacy Pierce Prize Lecture/

    Science.gov (United States)

    Kellogg, E. M.

    1975-01-01

    A review of results from the Uhuru satellite is presented. An intensive treatment of two subjects is given, rather than a broad review. First, Cyg X-1, a stellar X-ray source and a candidate for a black hole, is discussed; second, the X-ray source in the Perseus cluster of galaxies, which may be a cloud of hot intergalactic gas, is treated. In both cases, the train of logic used in establishing the nature of these objects is presented and evaluated. For both, while alternative explanations cannot be completely eliminated, they become more difficult to sustain when examined in detail, suggesting that the candidate explanations are more likely correct.

  2. Society News: Queen honours Fellows; The Society and legacies; Thesis prizes; Lectures on laptops; Stonehenge story

    Science.gov (United States)

    2007-08-01

    The Queen's Birthday Honours list announced on 16 June contained some familiar names from astronomy. Prof. Mark Bailey (1) of Armagh Observatory, currently a Vice-President of the RAS, was awarded an MBE and Dr Heather Couper (2), former President of the British Astronomical Association, a CBE. Prof. Nigel Mason (3) of the Open University and inaugural Director of the Milton Keynes Science Festival received an OBE. Prof. Jocelyn Bell-Burnell (4), President of the RAS from 2002-2004, was awarded a DBE - and an Honorary Doctorate from Harvard University. In addition, Prof. Lord Rees (5), Astronomer Royal, president of the Royal Society and President of the RAS from 1992-1994, was appointed to the Order of Merit.

  3. Davisson-Germer Prize in Atomic or Surface Physics Lecture: Exploring Flatland with Cold Atoms

    Science.gov (United States)

    Dalibard, Jean

    2012-06-01

    A two-dimensional Bose fluid is a remarkably rich many-body system, which allows one to revisit several features of quantum statistical physics. Firstly, the role of thermal fluctuations is enhanced compared to the 3D case, which destroys the ordered state associated with Bose-Einstein condensation. However interactions between particles can still cause a superfluid transition, thanks to the Berezinskii-Kosterlitz-Thouless mechanism. Secondly, a weakly interacting Bose fluid in 2D must be scale-invariant, a remarkable feature that manifests itself in the very simple form taken by the equation of state of the fluid. In this talk I will present recent experimental progress in the investigation of 2D atomic gases, which provide a nice illustration of the main features of low dimensional many-body physics.

  4. From rankings to mission.

    Science.gov (United States)

    Kirch, Darrell G; Prescott, John E

    2013-08-01

    Since the 1980s, school ranking systems have been a topic of discussion among leaders of higher education. Various ranking systems are based on inadequate data that fail to illustrate the complex nature and special contributions of the institutions they purport to rank, including U.S. medical schools, each of which contributes uniquely to meeting national health care needs. A study by Tancredi and colleagues in this issue of Academic Medicine illustrates the limitations of rankings specific to primary care training programs. This commentary discusses, first, how each school's mission and strengths, as well as the impact it has on the community it serves, are distinct, and, second, how these schools, which are each unique, are poorly represented by overly subjective ranking methodologies. Because academic leaders need data that are more objective to guide institutional development, the Association of American Medical Colleges (AAMC) has been developing tools to provide valid data that are applicable to each medical school. Specifically, the AAMC's Medical School Admissions Requirements and its Missions Management Tool each provide a comprehensive assessment of medical schools that leaders are using to drive institutional capacity building. This commentary affirms the importance of mission while challenging the leaders of medical schools, teaching hospitals, and universities to use reliable data to continually improve the quality of their training programs to improve the health of all.

  5. CERN exhibition wins yet another design prize

    CERN Multimedia

    Joannah Caborn Wengler

    2012-01-01

    The “Universe of Particles” exhibition in CERN’s Globe wins the silver design prize from the German direct business communications association FAMAB.   Not only do tens of thousands of people visit the “Universe of Particles” exhibition each year, but juries for design prizes are crossing its threshold more and more frequently too. In 2011 alone it claimed 8 awards, including winning outright the 2011 Annual Multimedia award, the iF Communication Design for Corporate Architecture award and the Modern Decoration Media award (the Bulletin already reported on some of these in July 2011). The FAMAB award is the latest to join the prestigious list. The jury of FAMAB’s “ADAM 2011” award was particularly impressed by the hands-on nature of the exhibition, which encourages visitors to get interested in science. They also appreciated the way that the space in the Globe is not just a container for the exhibits, but itself ...

  6. Robert Aymar awarded Global Energy prize

    CERN Multimedia

    2006-01-01

    CERN Director-General Robert Aymar was recently named one of three laureates of the 2006 Global Energy International Prize for 'the development of scientific and engineering foundation for the ITER project.' ITER is an experiment planned to be built in Europe at Cadarache (South of France) and designed to show the scientific and technological feasibility of a full-scale fusion power reactor. The other two laureates, who worked with Aymar on the project, are former President of the ITER Council, Russian Academician Evgeny Velikhov, and Japan's Dr Masaji Yoshikawa, ITER's former Vice President. Aymar headed ITER from 1994 to 2003. 'This prize is not only a great honour for me and my friends and colleagues of many years at ITER, Evgeny Velikhov and Masaji Yoshikawa,' Aymar said. 'It is above all a recognition of the effort of all those who have been involved with the ITER project and worked over the years to ensure the first step in proving that fusion will provide a new sustainable energy source for the plane...

  7. Public Lectures | Events | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Public and special lectures. Academy Public Lectures · Public and special lectures in Mid-Year and Annual Meetings · Platinum Jubilee Lectures. Academy's annual and mid-year meetings include a special lecture by a senior Fellow in the morning of each meeting day and one public lecture by an eminent person, from ...

  8. Dynamic Matrix Rank

    DEFF Research Database (Denmark)

    Frandsen, Gudmund Skovbjerg; Frandsen, Peter Frands

    2009-01-01

    We consider maintaining information about the rank of a matrix under changes of the entries. For n×n matrices, we show an upper bound of O(n1.575) arithmetic operations and a lower bound of Ω(n) arithmetic operations per element change. The upper bound is valid when changing up to O(n0.575) entries...... in a single column of the matrix. We also give an algorithm that maintains the rank using O(n2) arithmetic operations per rank one update. These bounds appear to be the first nontrivial bounds for the problem. The upper bounds are valid for arbitrary fields, whereas the lower bound is valid for algebraically...... closed fields. The upper bound for element updates uses fast rectangular matrix multiplication, and the lower bound involves further development of an earlier technique for proving lower bounds for dynamic computation of rational functions....

  9. Lectures on Quantum Gravity

    CERN Document Server

    Gomberoff, Andres

    2006-01-01

    The 2002 Pan-American Advanced Studies Institute School on Quantum Gravity was held at the Centro de Estudios Cientificos (CECS),Valdivia, Chile, January 4-14, 2002. The school featured lectures by ten speakers, and was attended by nearly 70 students from over 14 countries. A primary goal was to foster interaction and communication between participants from different cultures, both in the layman’s sense of the term and in terms of approaches to quantum gravity. We hope that the links formed by students and the school will persist throughout their professional lives, continuing to promote interaction and the essential exchange of ideas that drives research forward. This volume contains improved and updated versions of the lectures given at the School. It has been prepared both as a reminder for the participants, and so that these pedagogical introductions can be made available to others who were unable to attend. We expect them to serve students of all ages well.

  10. Lecture 2: Software Security

    CERN Multimedia

    CERN. Geneva

    2013-01-01

    Computer security has been an increasing concern for IT professionals for a number of years, yet despite all the efforts, computer systems and networks remain highly vulnerable to attacks of different kinds. Design flaws and security bugs in the underlying software are among the main reasons for this. This lecture addresses the following question: how to create secure software? The lecture starts with a definition of computer security and an explanation of why it is so difficult to achieve. It then introduces the main security principles (like least-privilege, or defense-in-depth) and discusses security in different phases of the software development cycle. The emphasis is put on the implementation part: most common pitfalls and security bugs are listed, followed by advice on best practice for security development, testing and deployment. Sebastian Lopienski is CERN’s deputy Computer Security Officer. He works on security strategy and policies; offers internal consultancy and audit services; develops and ...

  11. Globe: Lecture series

    CERN Multimedia

    2007-01-01

    The LHC: an accelerator of science This series of lectures is all about understanding the scientific and technological challenges of the phenomenal LHC project and assessing its innovations through their everyday applications. Come and take a sneak preview of the LHC! Communicate: the Grid, a computer of global dimensions François Grey, head of communication in CERN’s Information Technology Department How will it be possible for the 15 million billion bytes of data generated by the LHC every year to be handled and stored by a computer that doesn’t have to be the size of a skyscraper? The computer scientists have the answer: the Grid, which will harness the power of tens of thousands of computers all over the world by creating a network of computers and making them operate as one. >>> Lectures are free and require no specialist knowledge. In french. 
 >>> By reservation only: tel. +41 (0)22 767 76 76

  12. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    23, 24, 25, 26 and 27 April REGULAR LECTURE PROGRAMME From 11:00 hrs - Main Auditorium bldg. 500, on 23 April from 11:15 to 12:15 hrs Searches for Dark Matter F. Feinstein / CPPM, Marseille, F The fact that the mass of the visible stars could not account for the gravitational cohesion of the galaxy clusters was the first manifestation of non-radiating matter in the Universe. Since then, many observations imply that most of the matter is indeed dark. Its nature is still unknown and likely to have several contributions. Recent results indicate that most of it may not be composed of normal matter. These lectures will review the experimental methods, which have been developed to unravel this 70-year long mystery and confront their results with the current theoretical framework of cosmology.

  13. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Françoise Benz

    2002-01-01

    18, 19, 20, 21, 22 November LECTURE FOR POSTGRADUATE STUDENTS From 11:00 hrs - Main Auditorium bldg. 500 Telling the Truth with Statistics R. Barlow / Univ. of Manchester, UK This course of lectures will cover probability, distributions, fitting, errors and confidence levels, for practising High Energy Physicists who need to use Statistical techniques to express their results. Concentrating on these appropriate specialist techniques means that they can be covered in appropriate depth, while assuming only the knowledge and experience of a typical Particle Physicist. The different definitions of probability will be explained, and it will be appear why this basic subject is so controversial; there are several viewpoints and it is important to understand them all, rather than abusing the adherents of different beliefs. Distributions will be covered: the situations they arise in, their useful properties, and the amazing result of the Central Limit Theorem. Fitting a parametrisation to a set of data is one of the m...

  14. Schnabel Engineering Lecture

    OpenAIRE

    Cording, Edward

    2014-01-01

    Schnabel Engineering is pleased to bring you Dr. Edward J. Cording as our eighth lecturer of this series. Dr. Cording is Professor Emeritus of Civil and Environmental Engineering at the University of Illinois at Urbana-Champaign where he has taught and performed research in geotechnical engineering, focusing on rock mechanics, soil-structure interaction, and underground construction. The field has been his laboratory, on engineering projects; beginning in the 1960's with large deep caverns ...

  15. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    9, 10 and 11 May REGULAR LECTURE PROGRAMME From 10:00 to 12:00 hrs on 9 and 10 May and on 11 May from 11:00 to 12:00 hrs - Main Auditorium bldg. 500 Cosmology and Particle Physics K. Olive / CERN-TH A general overview of the standard big bang model will be presented with special emphasis on astro-particle physics. Specific topics will include: Inflation, Baryoogenesis, Nucleosynthesis and Dark Matter.

  16. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    2, 3, 4, 5 and 6 April REGULAR LECTURE PROGRAMME From 11:00 hrs - Main Auditorium bldg. 500 New Developments in Supersymmetry S. Raby / CERN-TH Introduction to supersymmetric grand unified theories. An introduction to the MSSM and different mechanisms for supersymmetry breaking. Then the details of SU(5) and SO(10) unification, the new gauge sector beyond the standard model, representations of quarks and leptons. Gauge and Yukawa coupling unification and some predictions.

  17. The video lecture

    OpenAIRE

    Crook, Charles; Schofield, Louise

    2017-01-01

    Vocabulary for describing the structures, roles, and relationships characteristic of traditional, or ‘offline’, education has been seamlessly applied to the designs of ‘online’ education. One example is the lecture, delivered as a video recording. The purpose of this research is to consider the concept of ‘lecture’ as realised in both offline and online contexts. We explore how media differences entail different student experiences and how these differences relate to design decisions associat...

  18. Lectures on LHC physics

    CERN Document Server

    Plehn, Tilman

    2012-01-01

    When we try to advance from a solid knowledge of field theory to LHC physics we usually encounter a frustrating problem: in particular Higgs physics and QCD techniques appear as a impenetrable granite block of phenomenological know-how, common lores, and historically grown intuition what works and what does not. I hope this lecture can drill a few holes into the rock and put you into a position to digest advanced writeups as well as some first research papers on the topic.

  19. B.Gregory Lecture

    CERN Multimedia

    Jacob,M

    1987-01-01

    Troisième série de "Gregory lectures" en mémoire de B.Gregory (1919-1977),DG de 1965 à 1970. La première conférence B.Gregory a été donné par le Prof.V.Weisskopf, son prédécesseur. Chris Greeg (?)de Berkley prend aussi la parole

  20. Two lectures on technicolor

    Energy Technology Data Exchange (ETDEWEB)

    Lane, K. [Fermi National Accelerator Lab., Batavia, IL (United States)]|[Boston Univ., MA (United States). Dept. of Physics

    2002-07-01

    These two lectures on technicolor and extended technicolor (ETC) were presented at l'Ecole de GIF at LAPP, Annecy-le-Vieux, France, in September 2001. In Lecture I, the motivation and structure of this theory of dynamical breaking of electroweak and flavor symmetries is summarized. The main phenomenological obstacles to this picture flavor-changing neutral currents, precision electroweak measurements, and the large top-quark mass-are reviewed. Then, their proposed resolutions-walking technicolor and top-color-assisted technicolor are discussed. In Lecture II, a scenario for CP violation is presented based on vacuum alignment for technifermions and quarks. It has the novel feature of CP violating phases that are rational multiples of {pi} to better than one part in 10{sup 10} without fine-tuning of parameters. The scheme thereby avoids light axions and a massless up quark. The mix ng of neutral mesons, the mechanism of top-quark mass generation, and the CP-violating parameters {epsilon} and sin(2{beta}) strongly constrain the form of ETC-generated quark mass matrices. (author)

  1. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    5, 6, 7, 8 and 9 March REGULAR LECTURE PROGRAMME From 11:00 hrs - Main Auditorium bldg. 500 Tracking at the LHC K. Safarik / CERN-EP The lecture will start with a short history of particle tracking in high-energy physics. Then we will concentrate on tracking in the LHC experiments. We will discuss various tracking devices proposed for these experiments, dividing them into two large groups: solid state detectors and gas detectors. Their characteristics, as well as their behaviour in different external conditions (i.e. magnetic field, radiation) will be compared. Furthermore, we will turn to the question: how to design a tracker using these various technologies, what are the essential parameters to be taken into account and we will apply these considerations to the proposed the LHC detectors. The last part of the lecture will be devoted to tracking software. We will mention simulation and concentrate on track finding and reconstruction, reviewing different algorithms prototyped for the LHC experiments. We will ...

  2. Most recent Web Lectures

    CERN Multimedia

    Steven Goldfarb

    Web Archives of ATLAS Plenary Sessions, Workshops, Meetings, and Tutorials recorded over the past two years are available via the University of Michigan portal here. Most recent additions include the ROOT Workshop held at CERN on March 26-27, the Physics Analysis Tools Workshop held in Bergen, Norway on April 23-27, and the CTEQ Workshop: "Physics at the LHC: Early Challenges" held at Michigan State University on May 14-15. Viewing requires a standard web browser with RealPlayer plug-in (included in most browsers automatically) and works on any major platform. Lectures can be viewed directly over the web or downloaded locally. In addition, you will find access to a variety of general tutorials and events via the portal. Suggestions for events or tutorials to record in 2007, as well as feedback on existing archives is always welcome. Please contact us at wlap@umich.edu. Thank you and enjoy the lectures! The Michigan Web Lecture Team Tushar Bhatnagar, Steven Goldfarb, Jeremy Herr, Mitch McLachlan, Homer A....

  3. Lectures for CERN pensioners

    CERN Multimedia

    SC Unit

    2008-01-01

    The CERN Medical Service and the Pensioners Association are pleased to invite CERN pensioners to a series of lectures given by professors and specialists from the Teaching Hospitals and the Faculty of Medicine of the University of Geneva on the following topic: PROMOTION OF OPTIMUM BRAIN AGEING The lectures will take place in the Main CERN Auditorium (Building 60) from 2.30 p.m. to 4.30 p.m. on the following dates: Wednesday 12 November 2008: Assessing the extent of brain ageing Dr Dina ZEKRY Friday 12 December 2008: Can memory decline be prevented? Pr Jean-Pierre MICHEL Thursday 15 January 2009: Diagnosing and treating Alzheimer’s disease Pr Gabriel GOLD Wednesday 25 February 2009: What is the brain reserve? Speaker’s name to be announced at a later date The lectures will be given in French, with transparencies in English, and will be followed by a wide-ranging debate with the participants. CERN Medical Service - Pensioners Association - CERN-ESO (GAC-EPA)

  4. Summer Student Lecture Programme

    CERN Multimedia

    2004-01-01

    Main Auditorium, bldg. 500 More Information DATE TIME LECTURER TITLE Wednesday 7 July 09:15 - 10:00 L. Fayard, O. Ullaland, D. Heagerty (CERN) Programme Presentation Workshops presentation Information on Computing Rules 10:15 - 11:00 R. Aymar (CERN) Introduction to CERN (1/2) 11:15 - 12:00 J. Engelen (CERN) Introduction to CERN (2/2) 15:00 - 16:30 H. Menzel (CERN) An Introduction to Radiation Protection DATE TIME LECTURER TITLE Thursday 8 july 09:15 - 10:00 L. Di Lella (CERN) Introduction to Particle Physics (1/4) 10:15 - 11:00 L. Di Lella (CERN) Introduction to Particle Physics (2/4) 11:15 - 12:00 P. Chomaz (GANIL / CERN) Fundamental questions in modern nuclear physics: The challenge of exotic nuclei (1/2) DATE TIME LECTURER TITLE Friday 9 July 09:15 - 10:00 L. Di Lella (CERN) Introduction to Particle Physics (3/4) 10:15 - 11:00 P. Chomaz (GANIL / CERN) Fundamental questions in modern nuclear physics: The challenge of exotic nuclei (2/2) 11:15 - 12:00 P....

  5. Diversifying customer review rankings.

    Science.gov (United States)

    Krestel, Ralf; Dokoohaki, Nima

    2015-06-01

    E-commerce Web sites owe much of their popularity to consumer reviews accompanying product descriptions. On-line customers spend hours and hours going through heaps of textual reviews to decide which products to buy. At the same time, each popular product has thousands of user-generated reviews, making it impossible for a buyer to read everything. Current approaches to display reviews to users or recommend an individual review for a product are based on the recency or helpfulness of each review. In this paper, we present a framework to rank product reviews by optimizing the coverage of the ranking with respect to sentiment or aspects, or by summarizing all reviews with the top-K reviews in the ranking. To accomplish this, we make use of the assigned star rating for a product as an indicator for a review's sentiment polarity and compare bag-of-words (language model) with topic models (latent Dirichlet allocation) as a mean to represent aspects. Our evaluation on manually annotated review data from a commercial review Web site demonstrates the effectiveness of our approach, outperforming plain recency ranking by 30% and obtaining best results by combining language and topic model representations. Copyright © 2015 Elsevier Ltd. All rights reserved.

  6. OutRank

    DEFF Research Database (Denmark)

    Müller, Emmanuel; Assent, Ira; Steinhausen, Uwe

    2008-01-01

    Outlier detection is an important data mining task for consistency checks, fraud detection, etc. Binary decision making on whether or not an object is an outlier is not appropriate in many applications and moreover hard to parametrize. Thus, recently, methods for outlier ranking have been proposed...

  7. Who can get the next Nobel Prize in infectious diseases?

    Directory of Open Access Journals (Sweden)

    Onder Ergonul

    2016-04-01

    Full Text Available The aim of this paper is to deliver a perspective on future Nobel prizes by reviewing the features of Nobel prizes awarded in the infectious diseases-related (IDR field over the last 115 years. Thirty-three out of 106 Nobel prizes (31% in Physiology or Medicine have been awarded for IDR topics. Out of 58 Nobel laureates for IDR topics, two have been female; 67% have been medical doctors. The median age of Nobel laureates in Physiology or Medicine was found to be lower than the median age of laureates in Literature (p < 0.001. Since the Second World War, US-affiliated scientists have dominated the Nobel prizes (53%; however before 1945, German scientists did so (p = 0.005. The new antimicrobials received Nobel prizes until 1960; however no treatment study was awarded the Prize until the discovery of artemisinin and ivermectin, for which the Nobel Prize was awarded in 2015. Collaborative works have increasingly been appreciated. In the future, more female laureates would be expected in the IDR field. Medical graduates and scientists involved in multi-institutional and multidisciplinary collaborative efforts seem to have an advantage.

  8. Prize level and debt size: impact on gambling behaviour.

    Science.gov (United States)

    Crewe-Brown, Courtney; Blaszczynski, Alex; Russell, Alex

    2014-09-01

    No studies to date have specifically determined the relationship between prize levels, debt size, and impulsivity on reported gambling behaviour on Electronic Gaming Machines (EGM). The present study reports the findings of a pilot study designed to investigate whether or not the likelihood of increasing the size of a bet was related to the level of prize offered and personal debt. The sample consisted of 171 first year psychology students (61 males and 120 females). Participants completed a series of gambling vignettes designed to elicit data on reported bet size according to different prize levels and debt sizes; the Eysenck Impulsivity Scale (Eysenck and Eysenck 1977); the Canadian Problem Gambling Index; and an author-constructed questionnaire eliciting data on demographic and gambling behaviours. Results indicated that as prize levels increase the odds (relative risk) of an individual placing a bet on an EGM and the amount of money reportedly bet tends to increase. A negative relationship between debt size and reported gambling behaviour moderated by prize level was found. No differences were found in the odds of placing a bet according to impulsivity. It was concluded that prize and debt sizes do influence propensities to gamble and level of bets. The findings have implications for restricting jackpot and general prize levels as a responsible gambling strategy designed to reduce motivations to gamble.

  9. The Ripple Effect: Citation Chain Reactions of a Nobel Prize

    DEFF Research Database (Denmark)

    Faber Frandsen, Tove; Nicolaisen, Jeppe

    2013-01-01

    This paper explores the possible citation chain reactions of a Nobel Prize using the mathematician Robert J. Aumann as a case example. The results show that the award of the Nobel Prize in 2005 affected not only the citations to his work, but also affected the citations to the references in his...... scientific oeuvre. The results indicate that the spillover effect is almost as powerful as the effect itself. We are consequently able to document a ripple effect in which the awarding of the Nobel Prize ignites a citation chain reaction to Aumann's scientific ouvre and to the references in its nearest...

  10. Improving Ranking Using Quantum Probability

    OpenAIRE

    Melucci, Massimo

    2011-01-01

    The paper shows that ranking information units by quantum probability differs from ranking them by classical probability provided the same data used for parameter estimation. As probability of detection (also known as recall or power) and probability of false alarm (also known as fallout or size) measure the quality of ranking, we point out and show that ranking by quantum probability yields higher probability of detection than ranking by classical probability provided a given probability of ...

  11. Conductive concrete wins Popular Science prize

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1997-06-01

    A conductive concrete developed by a research team at IRC (Institute for Research in Construction, National Research Council of Canada) has won a prize in the home technology category because of its possible use in heating homes. Following the award, there have been a number of inquiries regarding possible applications for the concrete. Greatest interests in the concrete have been in its potential to heat buildings by using it as flooring. Other possible applications included de-icing pavements to building warming pads for parking aircraft. Essentially, carbon fibres and conductive particles are added to a concrete mix in such a quantity that they form a network within the mix, ensuring high electrical conductivity. A demonstration project is underway to build a 20 by 80 foot conductive concrete pad to test the material`s capability as a snow removal and de-icing tool.

  12. Impact of abbreviated lecture with interactive mini-cases vs traditional lecture on student performance in the large classroom.

    Science.gov (United States)

    Marshall, Leisa L; Nykamp, Diane L; Momary, Kathryn M

    2014-12-15

    To compare the impact of 2 different teaching and learning methods on student mastery of learning objectives in a pharmacotherapy module in the large classroom setting. Two teaching and learning methods were implemented and compared in a required pharmacotherapy module for 2 years. The first year, multiple interactive mini-cases with inclass individual assessment and an abbreviated lecture were used to teach osteoarthritis; a traditional lecture with 1 inclass case discussion was used to teach gout. In the second year, the same topics were used but the methods were flipped. Student performance on pre/post individual readiness assessment tests (iRATs), case questions, and subsequent examinations were compared each year by the teaching and learning method and then between years by topic for each method. Students also voluntarily completed a 20-item evaluation of the teaching and learning methods. Postpresentation iRATs were significantly higher than prepresentation iRATs for each topic each year with the interactive mini-cases; there was no significant difference in iRATs before and after traditional lecture. For osteoarthritis, postpresentation iRATs after interactive mini-cases in year 1 were significantly higher than postpresentation iRATs after traditional lecture in year 2; the difference in iRATs for gout per learning method was not significant. The difference between examination performance for osteoarthritis and gout was not significant when the teaching and learning methods were compared. On the student evaluations, 2 items were significant both years when answers were compared by teaching and learning method. Each year, students ranked their class participation higher with interactive cases than with traditional lecture, but both years they reported enjoying the traditional lecture format more. Multiple interactive mini-cases with an abbreviated lecture improved immediate mastery of learning objectives compared to a traditional lecture format, regardless of

  13. Fractional cointegration rank estimation

    DEFF Research Database (Denmark)

    Lasak, Katarzyna; Velasco, Carlos

    We consider cointegration rank estimation for a p-dimensional Fractional Vector Error Correction Model. We propose a new two-step procedure which allows testing for further long-run equilibrium relations with possibly different persistence levels. The fi…rst step consists in estimating the parame......We consider cointegration rank estimation for a p-dimensional Fractional Vector Error Correction Model. We propose a new two-step procedure which allows testing for further long-run equilibrium relations with possibly different persistence levels. The fi…rst step consists in estimating...... to control for stochastic trend estimation effects from the first step. The critical values of the tests proposed depend only on the number of common trends under the null, p - r, and on the interval of the cointegration degrees b allowed, but not on the true cointegration degree b0. Hence, no additional...

  14. Lectures in Micro Meteorology

    DEFF Research Database (Denmark)

    Larsen, Søren Ejling

    This report contains the notes from my lectures on Micro scale meteorology at the Geophysics Department of the Niels Bohr Institute of Copenhagen University. In the period 1993-2012, I was responsible for this course at the University. At the start of the course, I decided that the text books...... available in meteorology at that time did not include enough of the special flavor of micro meteorology that characterized the work of the meteorology group at Risø (presently of the Institute of wind energy of the Danish Technical University). This work was focused on Boundary layer flows and turbulence...

  15. Joseph Mountin Lecture

    Centers for Disease Control (CDC) Podcasts

    2009-10-26

    In this podcast, William H. Foege, MD, MPH delivers the 29th Annual Joseph W. Mountin Lecture. Dr. Foege was a key leader in the smallpox effort and worked as an epidemiologist in the successful eradication campaign in the 1970s. Dr. Foege became chief of the Smallpox Eradication Program at CDC, and was appointed director of CDC in 1977.  Created: 10/26/2009 by Centers for Disease Control and Prevention (CDC).   Date Released: 10/29/2009.

  16. Lectures on electromagnetism

    CERN Document Server

    Das, Ashok

    2013-01-01

    These lecture notes on electromagnetism have evolved from graduate and undergraduate EM theory courses given by the author at the University of Rochester, with the basics presented with clarity and his characteristic attention to detail. The thirteen chapters cover, in logical sequence, topics ranging from electrostatics, magnetostatics and Maxwell's equations to plasmas and radiation. Boundary value problems are treated extensively, as are wave guides, electromagnetic interactions and fields. This second edition comprises many of the topics expanded with more details on the derivation of vari

  17. Lectures in particle physics

    CERN Document Server

    Green, Dan

    1994-01-01

    The aim of this book on particle physics is to present the theory in a simple way. The style and organization of the material is unique in that intuition is employed, not formal theory or the Monte Carlo method. This volume attempts to be more physical and less abstract than other texts without degenerating into a presentation of data without interpretation.This book is based on four courses of lectures conducted at Fermilab. It should prove very useful to advanced undergraduates and graduate students.

  18. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    26, 27, 28, 29 and 30 March REGULAR LECTURE PROGRAMME From 11:00 hrs - Main Auditorium bldg. 500 Introduction to General Relativity and Black Holes T. Damour / IHES, Bures-sur-Yvette, F. Conceptual foundations of General Relativity (GR). Uniqueness of GR. Mathematical framework: tensor calculus, Riemannian geometry, connection, 'spin' connection, curvature, Cartan's form calculus. Hilbert-Einstein action, Einstein equations. Weak gravitational fields. Post Newtonian Approximation. Gravitanional Waves. Exact solutions. Killing vectors. Experimental tests. Black Holes: extensions of the Schwarzschild solution; Kerr-Newman holes; no-hair theorems; energtics of black holes; the membrane approach; quantum mechanics of black holes; Bekenstein entropy; Hawking temperature; black holes and string theory.

  19. Lectures in scattering theory

    CERN Document Server

    Sitenko, A G

    1971-01-01

    Lectures in Scattering Theory discusses problems in quantum mechanics and the principles of the non-relativistic theory of potential scattering. This book describes in detail the properties of the scattering matrix and its connection with physically observable quantities. This text presents a stationary formulation of the scattering problem and the wave functions of a particle found in an external field. This book also examines the analytic properties of the scattering matrix, dispersion relations, complex angular moments, as well as the separable representation of the scattering amplitude. Th

  20. The Oskar Klein memorial lectures

    CERN Document Server

    1994-01-01

    The series of Oskar Klein Memorial Lectures is a must-read for those keenly involved or simply interested in exploring the many fascinating aspects of Physics. This volume presents two landmark lectures given by Hans Bethe in October 1990 and Alan H. Guth in June 1991 under the series of Oskar Klein Memorial Lectures. Hans Bethe's lectures dealt with two themes: the astrophysical importance of neutrinos in supernova outbursts and a theoretical account of neutrinos through observations of the neutrino flux from the centre of the sun. Anyone interested in understanding the processes involved in

  1. QUALITY LEADERS - LEARNING FROM THE DEMING PRIZE WINNERS IN INDIA

    Directory of Open Access Journals (Sweden)

    Jagadeesh Rajashekharaiah

    2014-09-01

    Full Text Available Different governments and professional agencies have set up a number of awards to recognize and reward quality initiatives. Deming Prize is one such award and ever since it was open for companies from outside Japan, maximum number of winning companies are from India, with 20 companies winning the Deming Prize and four among them also winning the Deming Grand Prize. This paper traces the path taken by these companies to know how these companies embarked a journey of Total Quality Management (TQM and reached their goal of winning the prestigious Deming Prize. The common working principles of these companies and the various tools and techniques used by them are described in a concise manner in this paper. Further, the paper highlights the lessons from these companies to inspire others. The data taken from the respective websites of the companies has been used to list out the objectives, methodologies, and the benefits accrued by the companies.

  2. Nobel Prize in Physics 2006-Cosmic Background Radiation and ...

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 12; Issue 2. Nobel Prize in Physics 2006 - Cosmic Background Radiation and Precision Cosmology. T Padmanabhan. General Article Volume 12 Issue 2 February 2007 pp 4-16 ...

  3. Recipients of 2013 EPS High Energy & Particle Physics Prize

    CERN Multimedia

    ATLAS, Experiment

    2014-01-01

    (From left) Joe Incandela, Peter Higgs, Francois Englert, Tejinder Virdee, Dave Charlton, and Peter Jenni. Higgs and Englert gave the prizes to the recipients of the 2013 European Physical Society's High Energy and Particle Physics Prize, for an outstanding contribution to high energy physics. "For the discovery of a Higgs boson, as predicted by the Brout-Englert-Higgs mechanism," the prize was awarded to the ATLAS and CMS collaborations. Spokesperson for CMS, Incandela, and Spokesperson for ATLAS, Charlton, accepted the awards on their collaborations' behalf. "For their pioneering and outstanding leadership roles in the making of the ATLAS and CMS experiments," the prize was awarded to Jenni, Virdee, and Michel Della Negra (not present). Image: ATLAS

  4. Iranian PhD student wins human-rights prize

    Science.gov (United States)

    Cartwright, Jon

    2013-11-01

    A physicist imprisoned in Iran while on a break from his PhD studies in the US has been awarded a human-rights prize. Omid Kokabee, who had been based at the University of Texas in Austin, has been given the Andrei Sakharov Prize from the American Physical Society (APS) for "his courage in refusing to use his physics knowledge to work on projects that he deemed harmful to humanity, in the face of extreme physical and psychological pressure".

  5. Lectures on Lie groups

    CERN Document Server

    Hsiang, Wu-Yi

    2017-01-01

    This volume consists of nine lectures on selected topics of Lie group theory. We provide the readers a concise introduction as well as a comprehensive 'tour of revisiting' the remarkable achievements of S Lie, W Killing, É Cartan and H Weyl on structural and classification theory of semi-simple Lie groups, Lie algebras and their representations; and also the wonderful duet of Cartans' theory on Lie groups and symmetric spaces.With the benefit of retrospective hindsight, mainly inspired by the outstanding contribution of H Weyl in the special case of compact connected Lie groups, we develop the above theory via a route quite different from the original methods engaged by most other books.We begin our revisiting with the compact theory which is much simpler than that of the general semi-simple Lie theory; mainly due to the well fittings between the Frobenius-Schur character theory and the maximal tori theorem of É Cartan together with Weyl's reduction (cf. Lectures 1-4). It is a wonderful reality of the Lie t...

  6. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    14, 15 and 16 May REGULAR LECTURE PROGRAMME 14, 15 May from 10:00 to 12:00 hrs - Main Auditorium bldg. 500 16 May from 11:00 to 12:00 hrs - Council Chamber, bldg 503 Modern Signal Processing: Wavelets vs. Fourier M. Vetterli / EPFL, Lausanne, CH and UC Berkeley Wavelets have established themselves as an important tool in modern signal processing as well as in applied mathematics. This is linked to several facts, among others: New theoretical advances have been achieved, like new forms of 4 time-frequency bases for signal analysis. Efficient computational algorithms are available. Many applications either used similar ideas, like for example the concept of multiresolution, or took advantage of the unified framework provided by wavelets. This combination of elegant theory, efficient algorithms, and successful applications makes the field of wavelets and signal processing quite exciting. It is the purpose of these lectures to establish the theory necessary to understand wavelets and related constructions. A...

  7. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    14, 15 and 16 May REGULAR LECTURE PROGRAMME 14, 15 May from 10:00 to 12:00 hrs - Main Auditorium bldg. 500 16 May from 11:00 to 12:00 hrs - Council Chamber, bldg 503 Modern Signal Processing: Wavelets vs. Fourier M. Vetterli / EPFL, Lausanne, CH and UC Berkeley Wavelets have established themselves as an important tool in modern signal processing as well as in applied mathematics. This is linked to several facts, among others: i. New theoretical advances have been achieved, like new forms of 4 time-frequency bases for signal analysis. ii. Efficient computational algorithms are available. iii. Many applications either used similar ideas, like for example the concept of multiresolution, or took advantage of the unified framework provided by wavelets. This combination of elegant theory, efficient algorithms, and successful applications makes the field of wavelets and signal processing quite exciting. It is the purpose of these lectures to establish the theory necessary to understand wavelets and related construct...

  8. SUMMER STUDENT LECTURE PROGRAMME

    CERN Multimedia

    Françoise Benz

    2002-01-01

    SUMMER STUDENT LECTURE PROGRAMME Main Auditorium, bldg. 500   DATE TIME LECTURER TITLE Monday 29 July 09:15 - 10:00 R. RATTAZZI Beyond the Standard Model (3/3) 10:15 - 11:00 P. WELLS Experimental test of the SM - LEP (3/3) 11:15 - 12:00 P. WELLS Discussion Session 14:00 - 16:00 R. ASSMANN The CLIC Concept for a Future Particle Collider at the Energy Frontier Tuesday 30 July 09:15 - 10:00 F. ANTINORI Heavy Ions (1/2) 10:15 - 12:00 F. DYDAK Neutrino Physics (1&2/4) Wednesday 31 July  09:15 - 10:00 F. ANTINORI Heavy Ions (2/2) 10:15 - 11:00 F. DYDAK Neutrino Physics (3/4) 11:15 - 12:00 F. DYDAK / F. ANTINORI Discussion Session Thursday 1 August 09:15 - 10:00 T. NAKADA CP Violation (1/4) 10:15 - 11:00 F. DYDAK Neutrino Physics (4/4) 11:15 - 12:00 F. BEDESCHI Experimental test of the SM Tevatron (1/2) Friday 2 August 09:15 - 10:00 T. NAKADA CP Violation (2/4) 10:15 ? 11:00 F. BEDESCHI Experimental test of the SM Tevatron (2/2) 11:15 ? 12:00 F. BEDESCHI / T. NAKADA Di...

  9. SUMMER STUDENT LECTURE PROGRAMME

    CERN Multimedia

    Françoise Benz

    2002-01-01

    Main Auditorium, bldg. 500   DATE TIME LECTURER TITLE Monday 5 August 09:15-10:00 F. GIANOTTI LHC Physics (1/3) 10:15-12:00 T. NAKADA CP Violation (3&4/4) Tuesday 6 August 09:15-10:00 F. GIANOTTI LHC Physics (2/3) 10:15-11:00 R. JACOBSEN From Raw Data to Physics Results (1/3) 11:15-12:00 R. JACOBSEN / T. NAKADA Discussion Session Wednesday 7 August 09:15-10:00 F. GIANOTTI LHC Physics (3/3) 10:15-11:00 R. JACOBSEN From Raw Data to Physics Results (2/3) 11:15-12:00 J. LESGOURDES Cosmology (1/4) 14:00-16:00 C. BENVENUTI Basic Science, Society, and Technological Innovation (Council Chamber, bldg. 503) Thursday 8 August 09:15-10:00 J. LESGOURDES Cosmology (2/4) 10:15-11:00 R. JACOBSEN From Raw Data to Physics Results (3/3) 11:15-12:00 J. CARR / J. LESGOURDES Discussion Session Friday 9 August 09:15-11:00 J. LESGOURDES Cosmology (3&4/4) 11:15-12:00 C. JARLSKOG Historic Lecture 14:00-16:00 Course Review Monday 12 August 09:15-12:00 Students Sessi...

  10. Lectures on Quantum Mechanics

    CERN Document Server

    Basdevant, Jean-Louis

    2007-01-01

    Beautifully illustrated and engagingly written, Lectures on Quantum Mechanics presents theoretical physics with a breathtaking array of examples and anecdotes. Basdevant's style is clear and stimulating, in the manner of a brisk classroom lecture that students can follow with ease and enjoyment. Here is a sample of the book's style, from the opening of Chapter 1: "If one were to ask a passer-by to quote a great formula of physics, chances are that the answer would be 'E = mc2'. Nevertheless, the formula 'E=hV' which was written in the same year 1905 by the same Albert Einstein, and which started quantum theory, concerns their daily life considerably more. In fact, of the three watershed years for physics toward the beginning of the 20th century - 1905: the Special Relativity of Einstein, Lorentz and Poincaré; 1915: the General Relativity of Einstein, with its extraordinary reflections on gravitation, space and time; and 1925: the full development of Quantum Mechanics - it is surely the last which has the mos...

  11. Volatility, house edge and prize structure of gambling games.

    Science.gov (United States)

    Turner, Nigel E

    2011-12-01

    This study used simulations to examine the effect of prize structure on the outcome volatility and the number of winners of various game configurations. The two most common prize structures found in gambling games are even money payoff games (bet $1; win $2) found on most table games and multilevel prizes structures found in gambling machine games. Simulations were set up to examine the effect of prize structure on the long-term outcomes of these games. Eight different prize structures were compared in terms of the number of winners and volatility. It was found that the standard table game and commercial gambling machines produced fairly high numbers of short term winners (1 h), but few long term winners (50 h). It was found that the typical even money game set up produced the lowest level of volatility. Of the multilevel prize structures examined, the three simulations based on commercial gambling machines were the least volatile. The results are examined in terms of the pragmatics of game design.

  12. Alfred Nobel and His Prizes: From Dynamite to DNA.

    Science.gov (United States)

    Lichtman, Marshall A

    2017-07-01

    Alfred Nobel was one of the most successful chemists, inventors, entrepreneurs, and businessmen of the late nineteenth century. In a decision later in life, he rewrote his will to leave virtually all his fortune to establish prizes for persons of any nationality who made the most compelling achievement for the benefit of mankind in the fields of chemistry, physics, physiology or medicine, literature, and peace among nations. The prizes were first awarded in 1901, five years after his death. In considering his choice of prizes, it may be pertinent that he used the principles of chemistry and physics in his inventions and he had a lifelong devotion to science, he suffered and died from severe coronary and cerebral atherosclerosis, and he was a bibliophile, an author, and mingled with the literati of Paris. His interest in harmony among nations may have derived from the effects of the applications of his inventions in warfare ("merchant of death") and his friendship with a leader in the movement to bring peace to nations of Europe. After some controversy, including Nobel's citizenship, the mechanisms to choose the laureates and make four of the awards were developed by a foundation established in Stockholm; the choice of the laureate for promoting harmony among nations was assigned to the Norwegian Storting, another controversy. The Nobel Prizes after 115 years remain the most prestigious of awards. This review describes the man, his foundation, and the prizes with a special commentary on the Nobel Prize in Physiology or Medicine.

  13. Chandra Telescope Designer Wins 2002 Rossi Prize

    Science.gov (United States)

    2002-01-01

    Leon Van Speybroeck of the Harvard-Smithsonian Center for Astrophysics in Cambridge, Massachusetts has been awarded the 2002 Bruno Rossi Prize of the High Energy Astrophysics Division of the American Astronomical Society. The Rossi Prize recognizes significant contributions in high-energy astrophysics. It is awarded annually in honor of the late Massachusetts Institute of Technology Professor Bruno Rossi, an authority on cosmic ray physics and a pioneer in the field of X-ray astronomy. The prize also includes an engraved certificate and a $1,500 award. Van Speybroeck, who led the effort to design and make the X-ray mirrors for NASA's premier X­ray observatory, the Chandra X-ray Observatory, was recognized for a career of stellar achievements in designing precision X-ray optics. As Telescope Scientist for Chandra, he has worked for more than 20 years with a team that includes scientists and engineers from the Harvard-Smithsonian, NASA's Marshall Space Flight Center, TRW, Inc., Hughes-Danbury (now B.F. Goodrich Aerospace), Optical Coating Laboratories, Inc., and Eastman-Kodak on all aspects of the X-ray mirror assembly that is the heart of the observatory. "Leon is one of the master mirror designers of our time," said Harvey Tananbaum, director of the Chandra X-ray Center. "His contributions were crucial to the spectacular success of the Chandra mission." The Chandra mirrors are the most precise mirrors ever made, smooth with tolerances of a few atoms. If the state of Colorado had the same relative smoothness as the surface of the Chandra X-ray Observatory mirrors, Pike's Peak would be less than an inch tall. The smoothness and alignment of the Chandra's mirrors are enabling scientists to make new discoveries about black holes, neutron stars, and galactic explosions. "Many, many other people made essential contributions to the Chandra program, and hopefully some of them will receive proper recognition," said Van Speybroeck. "In the meantime, I am thoroughly enjoying

  14. Banting Lecture 2009: An Unfinished Journey: Molecular Pathogenesis to Prevention of Type 1A Diabetes

    Science.gov (United States)

    Eisenbarth, George S.

    2010-01-01

    The Banting Medal for Scientific Achievement Award is the American Diabetes Association's highest scientific award and honors an individual who has made significant, long-term contributions to the understanding of diabetes, its treatment, and/or prevention. The award is named after Nobel Prize winner Sir Frederick Banting, who codiscovered insulin treatment for diabetes. Dr. Eisenbarth received the American Diabetes Association's Banting Medal for Scientific Achievement at the Association's 69th Scientific Sessions, June 5–9, 2009, in New Orleans, Louisiana. He presented the Banting Lecture, An Unfinished Journey—Type 1 Diabetes—Molecular Pathogenesis to Prevention, on Sunday, June 7, 2009. PMID:20350969

  15. Can College Rankings Be Believed?

    Directory of Open Access Journals (Sweden)

    Meredith Davis

    Full Text Available The article summarizes literature on college and university rankings worldwide and the strategies used by various ranking organizations, including those of government and popular media. It traces the history of national and global rankings, indicators used by ranking systems, and the effect of rankings on academic programs and their institutions. Although ranking systems employ diverse criteria and most weight certain indicators over others, there is considerable skepticism that most actually measure educational quality. At the same time, students and their families increasingly consult these evaluations when making college decisions, and sponsors of faculty research consider reputation when forming academic partnerships. While there are serious concerns regarding the validity of ranking institutions when so little data can support differences between one institution and another, college rankings appear to be here to stay.

  16. Ranking Baltic States Researchers

    Directory of Open Access Journals (Sweden)

    Gyula Mester

    2017-10-01

    Full Text Available In this article, using the h-index and the total number of citations, the best 10 Lithuanian, Latvian and Estonian researchers from several disciplines are ranked. The list may be formed based on the h-index and the total number of citations, given in Web of Science, Scopus, Publish or Perish Program and Google Scholar database. Data for the first 10 researchers are presented. Google Scholar is the most complete. Therefore, to define a single indicator, h-index calculated by Google Scholar may be a good and simple one. The author chooses the Google Scholar database as it is the broadest one.

  17. Sync-rank: Robust Ranking, Constrained Ranking and Rank Aggregation via Eigenvector and SDP Synchronization

    Science.gov (United States)

    2015-04-28

    eigenvector of the associated Laplacian matrix (i.e., the Fiedler vector) matches that of the variables. In other words, this approach (reminiscent of...S1), i.e., Dii = ∑n j=1Gi,j is the degree of node i in the measurement graph G. 3: Compute the Fiedler vector of S (eigenvector corresponding to the...smallest nonzero eigenvalue of LS). 4: Output the ranking induced by sorting the Fiedler vector of S, with the global ordering (increasing or decreasing

  18. Measuring revolutionary biomedical science 1992-2006 using Nobel prizes, Lasker (clinical medicine) awards and Gairdner awards (NLG metric).

    Science.gov (United States)

    Charlton, Bruce G

    2007-01-01

    The Nobel prize for medicine or physiology, the Lasker award for clinical medicine, and the Gairdner international award are given to individuals for their role in developing theories, technologies and discoveries which have changed the direction of biomedical science. These distinctions have been used to develop an NLG metric to measure research performance and trends in 'revolutionary' biomedical science with the aim of identifying the premier revolutionary science research institutions and nations from 1992-2006. I have previously argued that the number of Nobel laureates in the biomedical field should be expanded to about nine per year and the NLG metric attempts to predict the possible results of such an expansion. One hundred and nineteen NLG prizes and awards were made during the past fifteen years (about eight per year) when overlapping awards had been removed. Eighty-five were won by the USA, revealing a massive domination in revolutionary biomedical science by this nation; the UK was second with sixteen awards; Canada had five, Australia four and Germany three. The USA had twelve elite centres of revolutionary biomedical science, with University of Washington at Seattle and MIT in first position with six awards and prizes each; Rockefeller University and Caltech were jointly second placed with five. Surprisingly, Harvard University--which many people rank as the premier world research centre--failed to reach the threshold of three prizes and awards, and was not included in the elite list. The University of Oxford, UK, was the only institution outside of the USA which featured as a significant centre of revolutionary biomedical science. Long-term success at the highest level of revolutionary biomedical science (and probably other sciences) probably requires a sufficiently large number of individually-successful large institutions in open competition with one another--as in the USA. If this model cannot be replicated within smaller nations, then it implies

  19. ESP Methodology for Science Lecturers.

    Science.gov (United States)

    Rogers, Angela; Mulyana, Cukup

    A program designed to teach university science lecturers in Indonesia how to design and teach one-semester courses in English for special purposes (ESP) is described. The program provided lecturers with training in language teaching methodology and course design. The piloting of the teacher training course, focusing on physics instruction, is…

  20. Ranking the dermatology programs based on measurements of academic achievement.

    Science.gov (United States)

    Wu, Jashin J; Ramirez, Claudia C; Alonso, Carol A; Berman, Brian; Tyring, Stephen K

    2007-07-13

    The only dermatology rankings in the past were based on National Institutes of Health (NIH) funding and journal citations. To determine the highest ranking academic dermatology programs based on 5 outcome measures and on an overall ranking scale. To the best of our knowledge, this is the first report to rank the dermatology programs on 4 of the following outcome measures of academic achievement and with an overall ranking. We collected extensive 2001 to 2004 data ranging from total publications to grant funding on 107 U.S. dermatology programs and their full-time faculty. Data from part-time and volunteer faculty were not used. Publications in 2001 to 2004; NIH funding in 2004; Dermatology Foundation grants in 2001 to 2004; faculty lectures in 2004 delivered at national conferences; number of full-time faculty members who were on the editorial boards of the top 3 U.S. dermatology journals and the top 4 subspecialty journals We used the 5 outcome measures to tabulate the highest ranking programs in each category. Using a weighted ranking system, we also tabulated the overall top 30 dermatology programs based on these 5 outcome measures. We were not able to determine the total amount of NIH funding in dollars of the dermatology divisions. The impact factors of the journal in which these publications appeared was not factored into our calculations. Since faculty members may collaborate on the same publication, some publications may have been double-counted. In descending order, the 5 highest ranked academic programs are the University of Pennsylvania; University of California, San Francisco; Yale-New Haven Medical Center; New York University; and University of Michigan. This ranking system may allow residents and faculty to improve the academic achievements at their respective programs.

  1. Rankings from Fuzzy Pairwise Comparisons

    NARCIS (Netherlands)

    van den Broek, P.M.; Noppen, J.A.R.; Mohammadian, M.

    2006-01-01

    We propose a new method for deriving rankings from fuzzy pairwise comparisons. It is based on the observation that quantification of the uncertainty of the pairwise comparisons should be used to obtain a better crisp ranking, instead of a fuzzified version of the ranking obtained from crisp pairwise

  2. PageRank (II): Mathematics

    African Journals Online (AJOL)

    maths/stats

    INTRODUCTION. PageRank is Google's system for ranking web pages. A page with a higher PageRank is deemed more important and is more likely to be listed above a ... Felix U. Ogban, Department of Mathematics/Statistics and Computer Science, Faculty of Science, University of ..... probability, 2004, 41, (3): 721-734.

  3. University Rankings and Social Science

    Science.gov (United States)

    Marginson, Simon

    2014-01-01

    University rankings widely affect the behaviours of prospective students and their families, university executive leaders, academic faculty, governments and investors in higher education. Yet the social science foundations of global rankings receive little scrutiny. Rankings that simply recycle reputation without any necessary connection to real…

  4. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    8, 9, 10, 11 and 12 October LECTURES FOR POSTGRADUATE STUDENTS From 10:00 hrs - Main Auditorium bldg. 500 Introduction to Field Theory R. Kleiss / University of Nijmegen, NL Starting from the notion of path integrals as developed by Feynman, we discuss field theory in zero spacetime dimensions. The concepts of perturbation expansions, connected amplitudes, Feynman diagrams, classical solutions, renormalization and the effective action are developed. The model is extended to four spacetime dimensions, and the full Feynman rules for relativisitc scalar theory derived. The S matrix and the concept of unitarity are discussed, leading to the amputation rules for S matrix elements from considerations of unitarity. The rules are extended to include particles with spin-1/2 and spin-1. The high-energy behaviour of the theory is discussed as a method to derive the gauge symmetry of the various models.

  5. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    11, 12, 13, 14 and 15 June REGULAR LECTURE PROGRAMME From 11:00 hrs - Main Auditorium bldg. 500 What have we learned from LEP J. Ellis / CERN-TH The basic formalism of the Standard Model will be reviewed, and the limited state of our knowledge before the start-up of LEP will be recalled. Neutrino counting at LEP will be compared with astrophysical and cosmological constraints. The interpretation of precision electroweak data will be discussed, including their predictions for the top quark and the Higgs boson, and the hints they offer for the future direction beyond the Standard Model: probably a weakly-interacting theory that may be extrapolated up to a grand unification scale. Topics in QCD and heavy-flavour physics will be discussed briefly, and topics in W physics at greater length. Direct LEP searches for the Higgs boson and supersymmetric particles will be discussed, and the prospects for their discoveries at future accelerators will be previewed.

  6. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    19, 20, 21, 22 and 23 February REGULAR LECTURE PROGRAMME From 11:00 hrs - 19, 20 and 21 February Main Auditorium bldg. 500, 22 and 23 February Council Chamber, bldg 503 Introduction to Cryogenic Engineering J.G. Weisend / SLAC, Stanford, USA Cryogenic engineering is an important speciality at CERN. With the construction of LHC, this technology will have an even greater impact on machine operations. The goal of the course is to give people not working in cryogenics an appreciation of the basic principals and problems associated with the field. The course will also provide a foundation for future learning in cryogenics. Topics to be covered will include: properties of cryogenic fluids and materials, refrigeration, cryostat design, instrumentation, safety and propertiesof He II. Examples of working cryogenic systems, many of them from high energy physics, will be presented.

  7. Lectures on LHC physics

    CERN Document Server

    Plehn, Tilman

    2015-01-01

    With the discovery of the Higgs boson, the LHC experiments have closed the most important gap in our understanding of fundamental interactions, confirming that such interactions between elementary particles can be described by quantum field theory, more specifically by a renormalizable gauge theory. This theory is a priori valid for arbitrarily high energy scales and does not require an ultraviolet completion. Yet, when trying to apply the concrete knowledge of quantum field theory to actual LHC physics - in particular to the Higgs sector and certain regimes of QCD - one inevitably encounters an intricate maze of phenomenological know-how, common lore and other, often historically developed intuitions about what works and what doesn’t. These lectures cover three aspects to help understand LHC results in the Higgs sector and in searches for physics beyond the Standard Model: they discuss the many facets of Higgs physics, which is at the core of this significantly expanded second edition; then QCD, to the deg...

  8. Lectures on algebraic statistics

    CERN Document Server

    Drton, Mathias; Sullivant, Seth

    2009-01-01

    How does an algebraic geometer studying secant varieties further the understanding of hypothesis tests in statistics? Why would a statistician working on factor analysis raise open problems about determinantal varieties? Connections of this type are at the heart of the new field of "algebraic statistics". In this field, mathematicians and statisticians come together to solve statistical inference problems using concepts from algebraic geometry as well as related computational and combinatorial techniques. The goal of these lectures is to introduce newcomers from the different camps to algebraic statistics. The introduction will be centered around the following three observations: many important statistical models correspond to algebraic or semi-algebraic sets of parameters; the geometry of these parameter spaces determines the behaviour of widely used statistical inference procedures; computational algebraic geometry can be used to study parameter spaces and other features of statistical models.

  9. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    21, 22, 23 November LECTURES FOR POSTGRADUATE STUDENTS From 11:00 hrs - Council Chamber bldg. 503 on 21 November Auditorium, bldg 500 on 22, 23 November Introduction to symmetry breaking phenomena in physics E. Brezin / ENS, Paris, F. The notion of broken symmetries started slowly to emerge in the 19th century. The early studies of Pasteur on the parity asymmetry of life, the studies of Curie on piezoelectricity and on the symmetries of effects versus the symmetry of causes (which clearly excluded spontaneous symmetry breaking), are important historical landmarks. However the possibility of spontaneous symmetry breaking within the usual principles of statistical mechanics, waited for the work of Peierls and Onsager. The whole theory of phase transitions and critical phenomena, as well as the construction of field theoretic models as long distance limit of yet unknown physics, relies nowadays on the concept of criticality associated to spontaneous symmetry breaking. The phenomena of Goldstone bosons, of Meissn...

  10. Göttingen Lectures

    CERN Document Server

    Woyczyński, Wojbor A

    1998-01-01

    These lecture notes are woven around the subject of Burgers' turbulence/KPZ model of interface growth, a study of the nonlinear parabolic equation with random initial data. The analysis is conducted mostly in the space-time domain, with less attention paid to the frequency-domain picture. However, the bibliography contains a more complete information about other directions in the field which over the last decade enjoyed a vigorous expansion. The notes are addressed to a diverse audience, including mathematicians, statisticians, physicists, fluid dynamicists and engineers, and contain both rigorous and heuristic arguments. Because of the multidisciplinary audience, the notes also include a concise exposition of some classical topics in probability theory, such as Brownian motion, Wiener polynomial chaos, etc.

  11. Sequential rank agreement methods for comparison of ranked lists

    DEFF Research Database (Denmark)

    Ekstrøm, Claus Thorn; Gerds, Thomas Alexander; Jensen, Andreas Kryger

    2015-01-01

    The comparison of alternative rankings of a set of items is a general and prominent task in applied statistics. Predictor variables are ranked according to magnitude of association with an outcome, prediction models rank subjects according to the personalized risk of an event, and genetic studies...... are illustrated using gene rankings, and using data from two Danish ovarian cancer studies where we assess the within and between agreement of different statistical classification methods.......The comparison of alternative rankings of a set of items is a general and prominent task in applied statistics. Predictor variables are ranked according to magnitude of association with an outcome, prediction models rank subjects according to the personalized risk of an event, and genetic studies...

  12. An X-prize for transport airships

    Energy Technology Data Exchange (ETDEWEB)

    Hochstetler, R. [SAIC Canada, Ottawa, ON (Canada); Prentice, B.E. [Manitoba Univ., Winnipeg, MB (Canada). Transport Inst.

    2007-07-01

    Domestic air freight in the United States is expected to increase by at least 3 per cent every year for the next decade, while international demand will increase at twice that rate. As such, a new type of airship will be the most promising technological advance for the twenty-first century. Congestion in built up areas and demand for transport in remote areas has stimulated a resurgence of market interest in the potential value of lighter-than-air (LTA) vehicles for transport. Although most technical challenges have been addressed, the greatest challenge facing shippers is a lack of business confidence and policy directions to support investment in technology. Shippers are reluctant to commit the initial development funds needed to construct operational prototypes for testing. In 2004 and 2005, SAIC Canada conducted studies on airship technologies for the United States Army, and for use in the construction of oil and gas pipelines in remote regions. This paper presented a literature review of LTA technology as well as a brief market assessment. The criterion for an airship X-prize was then proposed as a challenge to stimulate the development of a transport airship capable of year round operations. It was concluded that transport airships offer a more benign system of transport that reduce greenhouse gases and provide a means of mitigating the damages done by existing transport services. 5 refs.

  13. Physics GRE Scores of Prize Postdoctoral Fellows in Astronomy

    CERN Document Server

    Levesque, Emily M; Tremblay, Grant R

    2015-01-01

    The Physics GRE is currently a required element of the graduate admissions process in nearly all U.S. astronomy programs; however, its predictive power and utility as a means of selecting "successful" applicants has never been examined. We circulated a short questionnaire to 271 people who have held U.S. prize postdoctoral fellowships in astrophysics between 2010-2015, asking them to report their Physics GRE scores (this should not in any way be interpreted as a belief that a prize fellowship is the best or only metric of "success" in astronomy). The response rate was 64%, and the responding sample is unbiased with respect to the overall gender distribution of prize fellows. The responses reveal that the Physics GRE scores of prize fellows do not adhere to any minimum percentile score and show no statistically significant correlation with the number of first author papers published. As an example, a Physics GRE percentile cutoff of 60% would have eliminated 44% of 2010-2015 U.S. prize postdoctoral fellows, in...

  14. Pomeranchuk Prize awarded to André Martin

    CERN Multimedia

    Jordan Juras

    2010-01-01

    Professor André Martin has been awarded the I.Ya.Pomeranchuk Prize 2010, alongside Professor Valentine Zakharov.   André Martin, CERN theorist, pictured at the ceremony held in honour of his 80th birthday (August 2009). Established by the Institute of Theoretical and Experimental Physics (ITEP) in memory of an outstanding scientist Isaak Yakovlevich Pomeranchuk, the prize is awarded for the study of analytic properties of the scattering amplitude; which lead to the Froissart—Martin bound on the cross section growth with energy. The prize comes as a great honor for Martin, who was in fact a good friend of Mr. Pomeranchuk, "I am surprised and delighted to learn that I will be receiving the 2010 Pomeranchuk Prize. I was an admirer of Pomeranchuk and we shared a great friendship. I met with him for the last time in Erevan (Armenia) in 1965. As a good-bye, he told me, 'Analyticity exists'. This is precisely what I proved to earn the prize"....

  15. Ranking nodes in growing networks: When PageRank fails.

    Science.gov (United States)

    Mariani, Manuel Sebastian; Medo, Matúš; Zhang, Yi-Cheng

    2015-11-10

    PageRank is arguably the most popular ranking algorithm which is being applied in real systems ranging from information to biological and infrastructure networks. Despite its outstanding popularity and broad use in different areas of science, the relation between the algorithm's efficacy and properties of the network on which it acts has not yet been fully understood. We study here PageRank's performance on a network model supported by real data, and show that realistic temporal effects make PageRank fail in individuating the most valuable nodes for a broad range of model parameters. Results on real data are in qualitative agreement with our model-based findings. This failure of PageRank reveals that the static approach to information filtering is inappropriate for a broad class of growing systems, and suggest that time-dependent algorithms that are based on the temporal linking patterns of these systems are needed to better rank the nodes.

  16. Ecosystems Vulnerability Challenge and Prize Competition

    Science.gov (United States)

    Smith, J. H.; Frame, M. T.; Ferriter, O.; Recker, J.

    2014-12-01

    Stimulating innovation and private sector entrepreneurship is an important way to advance the preparedness of communities, businesses and individuals for the impacts of climate change on certain aspects of ecosystems, such as: fire regimes; water availability; carbon sequestration; biodiversity conservation; weather-related hazards, and the spread of invasive species. The creation of tools is critical to help communities and natural resource managers better understand the impacts of climate change on ecosystems and the potential resulting implications for ecosystem services and conservation efforts. The Department of the Interior is leading an interagency effort to develop the Ecosystems Vulnerability theme as part of the President's Climate Action Plan. This effort will provide seamless access to relevant datasets that can help address such issues as: risk of wildfires to local communities and federal lands; water sensitivity to climate change; and understanding the role of ecosystems in a changing climate. This session will provide an overview of the proposed Ecosystem Vulnerability Challenge and Prize Competition, outlining the intended audience, scope, goals, and overall timeline. The session will provide an opportunity for participants to offer new ideas. Through the Challenge, access will be made available to critical datasets for software developers, engineers, scientists, students, and researchers to develop and submit applications addressing critical science issues facing our Nation today. Application submission criteria and guidelines will also be discussed. The Challenge will be open to all sectors and organizations (i.e. federal, non-federal, private sector, non-profits, and universities) within the United States. It is anticipated the Challenge will run from early January 2015 until spring of 2015.

  17. Neophilia Ranking of Scientific Journals

    Science.gov (United States)

    Packalen, Mikko; Bhattacharya, Jay

    2017-01-01

    The ranking of scientific journals is important because of the signal it sends to scientists about what is considered most vital for scientific progress. Existing ranking systems focus on measuring the influence of a scientific paper (citations)—these rankings do not reward journals for publishing innovative work that builds on new ideas. We propose an alternative ranking based on the proclivity of journals to publish papers that build on new ideas, and we implement this ranking via a text-based analysis of all published biomedical papers dating back to 1946. In addition, we compare our neophilia ranking to citation-based (impact factor) rankings; this comparison shows that the two ranking approaches are distinct. Prior theoretical work suggests an active role for our neophilia index in science policy. Absent an explicit incentive to pursue novel science, scientists underinvest in innovative work because of a coordination problem: for work on a new idea to flourish, many scientists must decide to adopt it in their work. Rankings that are based purely on influence thus do not provide sufficient incentives for publishing innovative work. By contrast, adoption of the neophilia index as part of journal-ranking procedures by funding agencies and university administrators would provide an explicit incentive for journals to publish innovative work and thus help solve the coordination problem by increasing scientists' incentives to pursue innovative work. PMID:28713181

  18. John Adams Lecture

    CERN Multimedia

    PH Department

    2010-01-01

    13 December 2010 14:30 - Council Chamber, Bldg.503-1-001 Accelerator Breakthroughs, Achievements and Lessons from the Tevatron Collider V. Shiltsev / Fermilab’s Accelerator Physics Centre This year we celebrate the 25th anniversary of the first proton-antiproton collisions in the Tevatron. For two and a half decades the Tevatron at Fermilab (Batavia, IL, USA) was a centerpiece of the US and world’s High Energy Physics as the world’s highest energy particle collider at 1.8 TeV center of mass energy. While funding agencies are deciding on a 3-year extension of the Collider Run II operation through 2014, we – in this 2010 John Adams Lecture - will take a look in exciting story of the Tevatron: the story of long preparations, great expectations, numerous difficulties, years of “blood and sweat”, continuous upgrades, exceeding original goals (by a factor of 400) and high emotions. An accelerator scientist prospective will be given on a wide spectrum o...

  19. SUMMER STUDENT LECTURE PROGRAMME

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    Main Auditorium bldg. 500 Date Time Lecturer Title Monday 30 July 9:15 10:15 11:15 G. Guidice / CERN T. Nakada / CERN P. Wells / CERN Beyond the Standard Model (1/3) Violation of Particle Anti-particle Symmetry (3/3) LEP Physics (3/4) Tuesday 31 July 9:15 10:15 11:15 G. Guidice / CERN F. Dydak / CERN P. Wells / CERN P. Lebrun / CERN P. Lebrun / CERN Beyond the Standard Model (2/3) Neutrino Physics (1/4) LEP Physics (4/4) Superconducting Technology for particle accelerators (1/2) Superconducting Technology for particle accelerators (2/2) Wednesday 1 August 9:15 10:15 11:15 G. Guidice / CERN F. Dydak / CERN G. Guidice; P. Wells G. Guidice in main auditorium, P. Wells in TH auditorium) O. Grobner / CERN O. Grobner / CERN Beyond the Standard Model (3/3) Neutrino Physics (2/4) Discussion Session Ultra High Vacuum Technology (1/2) Ultra High Vacuum Technology (2/2) Thursday 2 August 9:15 10:15 11:15 F. Antinori / CERN F. Dydak / CERN J. Aysto / CERN Heavy Ions (1/2) Neutrino Physics (3/4) Isolde Physics O...

  20. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel. 73127

    2002-01-01

    14, 15, 16, 17, 18 January LECTURE SERIES From 11:00 hrs - Auditorium, bldg 500 Superconducting materials suitable for magnets D.C. Larbalestier / Univ. of Wisconsin, USA The range of materials available for superconducting magnets is steadily expanding, even as the choice of material becomes potentially more complex. When virtually all magnets were cooled by helium at ~2-5 K it was easy to separate the domain of Nb-Ti from those of Nb3Sn applications and very little surprise that more than 90% of all magnets are still made from Nb-Ti. But the development of useful conductors of the Bi-Sr-Ca-Cu-O and YBa2Cu3Ox high temperature superconductors, coupled to the recent discovery of the 39 K superconductor MgB2 and the developing availability of cryocoolers suggests that new classes of higher temperature, medium field magnets based on other than Nb-based conductors could become available in the next 5-10 years. My talks will discuss the essential physics and materials science of these 5 classes of material - Nb-Ti...

  1. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    14, 15, 16, 17, 18 January LECTURES FOR POSTGRADUATE STUDENTS From 11:00 hrs - Auditorium, bldg 500 Superconducting materials suitable for magnets D.C. Larbalestier / Univ. of Wisconsin, USA The range of materials available for superconducting magnets is steadily expanding, even as the choice of material becomes potentially more complex. When virtually all magnets were cooled by helium at ~2-5 K it was easy to separate the domain of Nb-Ti from those of Nb3Sn applications and very little surprise that more than 90% of all magnets are still made from Nb-Ti. But the development of useful conductors of the Bi-Sr-Ca-Cu-O and YBa2Cu3Ox high temperature superconductors, coupled to the recent discovery of the 39 K superconductor MgB2 and the developing availability of cryocoolers suggests that new classes of higher temperature, medium field magnets based on other than Nb-based conductors could become available in the next 5-10 years. My talks will discuss the essential physics and materials science of these 5 classes...

  2. ACADEMIC TRAINING LECTURE

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    27, 28, 29 June and 2, 3 July REGULAR LECTURE PROGRAMME From 11:00 hrs - Council Chamber bldg. 503 on 27, 28, 29 June and Auditorium, bldg 500 on 2, 3 July Particle Identification at the LHC P. Eerola / Lund University, SE The LHC experiments will explore new frontiers of particle physics. To maximize the physics potential of LHC, we need identification of leptons, hadrons, photons and 'invisible' particles. This is realized through reconstruction of electrons and muons, charged particle tracking and identification, b- and tau-tagging, and jet reconstruction. In addition, missing energy has to be measured in order to look for signatures of invisible particles. The experimental conditions posed by the collider, which will be operating at higher energy and luminosity than the present ones, are demanding. A large dynamical range is required in order to measure energies and momenta ranging from below one GeV to several TeVs. The detectors should be able to cope with the 40 MHz collision rate, with a large number ...

  3. SUMMER STUDENT LECTURE PROGRAMME

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    Main Auditorium bldg. 500 Date Time Lecturer Title Wednesday 4 July 9:15 10:15 11:15 14:00 15:00 15:45 L. Maiani / CERN L. Maiani / CERN M. Franklin / CERN G. Stevenson M. Diemoz O. Ullaland Introduction to CERN & Particle Physics (1/2) Introduction to CERN & Particle Physics (2/2) Classic Experiments (1/3) CERN Radiation Protection CERN Information on Activities CERN Intro to workshops Thursday 5 July 9:15 10:15 11:15 14:00 15:00 16:30 M. Franklin / CERN M. Franklin / CERN M. Franklin / CERN F. Close F. Close   Classic Experiments (2/3) Classic Experiments (3/3) Discussion session Particle Physics (for non-physics students) (1/4) Particle Physics (for non-physics students) (2/4) Welcome Drink Friday 6 July 9:15 10:15 F. Close F. Close Particle Physics (for non-physics students) (3/4) Particle Physics (for non-physics students) (4/4) Monday 9 July 9:15 10:15 11:15 R. Kleiss / CERN L. Rolandi / CERN L. Rolandi / CERN Fundamental Concepts of Particle Physics (1/6) Big Experime...

  4. SUMMER STUDENT LECTURE PROGRAMME

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    Main Auditorium bldg. 500 Date Time Lecturer Title Monday 9 July 9:15 10:15 11:15 R. Kleiss / CERN L. Rolandi / CERN L. Rolandi / CERN Fundamental Concepts of Particle Physics (1/6) Big Experiments Discussion Session Tuesday 10 July 9:15 10:15 11:15 R. Kleiss / CERN R. Kleiss / CERN C. Joram Fundamental Concepts of Particle Physics (2/6) Fundamental Concepts of Particle Physics (3/6) Particle Detectors (1/5) Wednesday 11 July 9:15 10:15 11:15 R. Kleiss / CERN C. Joram / CERN R. Kleiss / C. Joram Fundamental Concepts of Particle Physics (4/6) Particle Detectors (2/5) Discussion Session Thursday 12 July 9:15 10:15 11:15 R. Kleiss / CERN C. Joram / CERN C. Joram / CERN Fundamental Concepts of Particle Physics (5/6) Particle Detectors (3/5) Particle Detectors (4/5) Friday 13 July 9:15 10:15 11:15 R. Kleiss / CERN C. Joram / CERN R. Kleiss / C. Joram Fundamental Concepts of Particle Physics (6/6) Particle Detectors (5/5) Discussion Session Monday 16 July 9:15 10:15 11:15 A. Pich O. Brüning C...

  5. SUMMER STUDENT LECTURE PROGRAMME

    CERN Multimedia

    Françoise Benz

    2002-01-01

    Main Auditorium, bldg. 500   DATE TIME LECTURER TITLE Monday 22 July 09:15 - 10:00 A. PICH Standard Model (6/8) 10:15 - 11:00 J. CARR  Astroparticles (1/3) 11:15 - 12:00 J. SHIERS Computing (1/3) Tuesday 23 July 09:15 - 10:00 A. PICH Standard Model (7/8) 10:15 - 11:00 J. CARR  Astroparticles (2/3) 11:15 - 12:00 J. SHIERS Computing (2/3) Wednesday 24July 09:15 - 10:00 A. PICH Standard Model (8/8) 10:15 - 11:00 J. CARR  Astroparticles (3/3) 11:15 - 12:00 Discussion Session 14:00 - 16:00 O. GROBNER UHV Technology Thursday 25 July (Theory Auditorium) 09:15 - 10:00 R. RATTAZZI Beyond the Standard Model (1/3) (TH) 10:15 - 11:00 P. WELLS Experimental test of the SM - LEP (1/3) (TH) 11:15 - 12:00 J. SHIERS Computing (3/3) (TH) Friday 26 July 09:15 - 10:00 R. RATTAZZI Beyond the Standard Model (2/3) 10:15 - 11:00 P. WELLS Experimental test of the SM - LEP (2/3) 11:15 - 12:00 Discussion Session Monday 29 July 09:15 - 10:00  R...

  6. SUMMER STUDENT LECTURE PROGRAMME

    CERN Multimedia

    Academic Training; Tel. 73127

    2001-01-01

    Main Auditorium bldg. 500 Date Time Lecturer Title Monday 6 August 9:15 10:15 11:15 F. Gianotti / CERN J. Carr / CERN E. Copeland / Centre for Theoretical Physics University of Sussex, UK LHC Physics (1/3) Astroparticle Physics (1/3) Introduction to Cosmology (1/2) Tuesday 7 August 9:15 10:15 11:15 14:00 15:00 F. Gianotti / CERN J. Carr / CERN E. Copeland / Centre for Theoretical Physics University of Sussex, UK LHC Physics (2/3) Astroparticle Physics (2/3) Introduction to Cosmology (2/2) Wednesday 8 August 9:15 10:15 11:15 14:00 15:00 F. Gianotti / CERN J. Carr / CERN J. Carr; F. Gianotti J. Carr in main auditorium F. Gianotti in TH auditorium LHC Physics (2/3) Astroparticle Physics (2/3) Discussion Session Thursday 9 August 9:15 10:15 11:15 G. Veneziano / CERN G. Veneziano; E. Copeland G. Veneziano in main auditorium E. Copeland in TH auditorium Dreams of a Finite Theory (1/2) Student Session (1/3) Discussion Session Friday 10 August 9:15 10:15 11:15 G. Veneziano / CERN L. Okun / CERN Student Se...

  7. Lectures on general relativity

    CERN Document Server

    Papapetrou, Achille

    1974-01-01

    This book is an elaboration of lecture notes for the graduate course on General Rela­ tivity given by the author at Boston University in the spring semester of 1972. It is an introduction to the subject only, as the time available for the course was limited. The author of an introduction to General Relativity is faced from the beginning with the difficult task of choosing which material to include. A general criterion as­ sisting in this choice is provided by the didactic character of the book: Those chapters have to be included in priority, which will be most useful to the reader in enabling him to understand the methods used in General Relativity, the results obtained so far and possibly the problems still to be solved. This criterion is not sufficient to ensure a unique choice. General Relativity has developed to such a degree, that it is impossible to include in an introductory textbook of a reasonable length even a very condensed treatment of all important problems which have been discussed unt...

  8. 77 FR 58114 - SunShot Prize: Race to the Rooftop

    Science.gov (United States)

    2012-09-19

    ...This notice announces the release of the SunShot Prize: Race to the Rooftop competition. This competition offers $10 million in prizes to those who can lower the non-hardware installation cost of rooftop solar energy systems.

  9. 77 FR 56697 - Culturally Significant Objects Imported for Exhibition Determinations: “The English Prize: The...

    Science.gov (United States)

    2012-09-13

    ... for Exhibition Determinations: ``The English Prize: The Capture of the Westmorland, an Episode of the..., 2003), I hereby determine that the objects to be included in the exhibition ``The English Prize: The...

  10. Stakeholder Perspectives on Citation and Peer-Based Rankings of Higher Education Journals

    Science.gov (United States)

    Wilkins, Stephen; Huisman, Jeroen

    2015-01-01

    The purpose of this article is to identify and discuss the possible uses of higher education journal rankings, and the associated advantages and disadvantages of using them. The research involved 40 individuals--lecturers, university managers, journal editors and publishers--who represented a range of stakeholders involved with research into…

  11. W K H Panofsky prize awarded for CP violation

    CERN Multimedia

    2006-01-01

    Italo Mannelli (left) et Heinrich Wahl (right) at CERN after the announcement of the prize. The American Physical Society has recently announced its 2007 winners of the W K H Panofsky prize to CERN's Heinrich Wahl (now at the University of Ferrara), Italo Mannelli from Scuola Normale Superiore di Pisa and Bruce Winstein of University of Chicago. These three physicists led experiments that resulted in a multitude of precision measurements of properties of neutral kaons, most notably the discovery of direct CP violation. The W K H Panofsky prize recognizes outstanding achievements in experimental particle physics. Wahl and Mannelli's important work at CERN with CP violation and neutral kaons in the 1970s paved the way for the NA31 experiment in the 1980s. This experiment, of which Wahl was the spokesperson, focused on and found the first evidence for direct CP violation. Mannelli played a leading role, particularly in implementing his knowledge of calorimetry using liquefied noble gases, a technique originally...

  12. Club of Bologna International Best PhD Prize 2012

    Directory of Open Access Journals (Sweden)

    Marco Fiala

    2012-06-01

    Full Text Available The Club of Bologna, in collaboration with UNACOMA, will be awarding a prize for the best PhD theses on subjects related to agricultural machinery design and development. Up to ten theses will be selected and the best five of these will have the chance of being presented during the annual Club of Bologna meeting that will be held from 9 to 10 November 2012, on occasion of the EIMA. The authors of the best three PhD theses will also receive a cash prize. The winners will be guests in Bologna of UNACOMA who will cover travelling expenses and hotel accommodation for 2 nights. They will also meet farm machinery manufacturers attending the international trade fair. The winners of the Club of Bologna Prize 2012 will be announced here. Application forms and further information can be downloaded from the Club of Bologna website (http://www.clubofbologna.org/.

  13. Romanians and the Nobel Prizes for Science and Literature

    Directory of Open Access Journals (Sweden)

    Vasilica Sirbu

    2012-08-01

    Full Text Available There is much to be said about the Nobel Prizes. Numerous pages are written each year to promote, describe, analyze and criticize the prizes, their initiator and their evolution since 1901. The purpose of this study is to bring back to light from the dust of the archives information about those Romanians who were ahead of their times through their outstanding thinking and understanding of the world. Little has been written about those nominated, since it has been considered more relevant to focus on the winners. There were plentiful creative minds who only needed an opportunity to be known to the world. Famous Romanian names show up from the archives and the nomination database provided by the Nobel Institution and enable us to get a broad perspective of the nominators and the nominees. Ironically, as in the case of the Nobel Peace Prize, most of those who genuinely had a chance to win were never nominated.

  14. Wikipedia ranking of world universities

    Science.gov (United States)

    Lages, José; Patt, Antoine; Shepelyansky, Dima L.

    2016-03-01

    We use the directed networks between articles of 24 Wikipedia language editions for producing the wikipedia ranking of world Universities (WRWU) using PageRank, 2DRank and CheiRank algorithms. This approach allows to incorporate various cultural views on world universities using the mathematical statistical analysis independent of cultural preferences. The Wikipedia ranking of top 100 universities provides about 60% overlap with the Shanghai university ranking demonstrating the reliable features of this approach. At the same time WRWU incorporates all knowledge accumulated at 24 Wikipedia editions giving stronger highlights for historically important universities leading to a different estimation of efficiency of world countries in university education. The historical development of university ranking is analyzed during ten centuries of their history.

  15. Low-rank coal research

    Energy Technology Data Exchange (ETDEWEB)

    Weber, G. F.; Laudal, D. L.

    1989-01-01

    This work is a compilation of reports on ongoing research at the University of North Dakota. Topics include: Control Technology and Coal Preparation Research (SO{sub x}/NO{sub x} control, waste management), Advanced Research and Technology Development (turbine combustion phenomena, combustion inorganic transformation, coal/char reactivity, liquefaction reactivity of low-rank coals, gasification ash and slag characterization, fine particulate emissions), Combustion Research (fluidized bed combustion, beneficiation of low-rank coals, combustion characterization of low-rank coal fuels, diesel utilization of low-rank coals), Liquefaction Research (low-rank coal direct liquefaction), and Gasification Research (hydrogen production from low-rank coals, advanced wastewater treatment, mild gasification, color and residual COD removal from Synfuel wastewaters, Great Plains Gasification Plant, gasifier optimization).

  16. Posters of the 2013 Nobel Prize in Physics available from the Library

    CERN Multimedia

    CERN Library

    2014-01-01

    The Royal Swedish Academy of Sciences produces three posters annually, each of which explains the motivation for the award of the Nobel prizes in Physics, Chemistry and Economics.   The files of the posters are available here: http://www.kva.se/en/Prizes/Nobel-prizes/Nobel-Posters/ The good news is that the CERN Library has got a stock of posters of the 2013 Nobel Prize in Physics. They are available free from the Library (52-1-052).

  17. Alfred Nobel and His Prizes: From Dynamite to DNA

    Directory of Open Access Journals (Sweden)

    Marshall A. Lichtman

    2017-07-01

    Full Text Available Alfred Nobel was one of the most successful chemists, inventors, entrepreneurs, and businessmen of the late nineteenth century. In a decision later in life, he rewrote his will to leave virtually all his fortune to establish prizes for persons of any nationality who made the most compelling achievement for the benefit of mankind in the fields of chemistry, physics, physiology or medicine, literature, and peace among nations. The prizes were first awarded in 1901, five years after his death. In considering his choice of prizes, it may be pertinent that he used the principles of chemistry and physics in his inventions and he had a lifelong devotion to science, he suffered and died from severe coronary and cerebral atherosclerosis, and he was a bibliophile, an author, and mingled with the literati of Paris. His interest in harmony among nations may have derived from the effects of the applications of his inventions in warfare (“merchant of death” and his friendship with a leader in the movement to bring peace to nations of Europe. After some controversy, including Nobel’s citizenship, the mechanisms to choose the laureates and make four of the awards were developed by a foundation established in Stockholm; the choice of the laureate for promoting harmony among nations was assigned to the Norwegian Storting, another controversy. The Nobel Prizes after 115 years remain the most prestigious of awards. This review describes the man, his foundation, and the prizes with a special commentary on the Nobel Prize in Physiology or Medicine.

  18. Public Lectures | Events | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Public and special lectures in Mid-Year and Annual Meetings. Academy Public Lectures · Public and special lectures in Mid-Year and Annual Meetings · Platinum Jubilee Lectures. Single molecule spectroscopy of a single live cell. Kankan Bhattacharyya Pune, 8 November 2015 (81st Annual Meeting). Pulse to planet: ...

  19. Statistical methods for ranking data

    CERN Document Server

    Alvo, Mayer

    2014-01-01

    This book introduces advanced undergraduate, graduate students and practitioners to statistical methods for ranking data. An important aspect of nonparametric statistics is oriented towards the use of ranking data. Rank correlation is defined through the notion of distance functions and the notion of compatibility is introduced to deal with incomplete data. Ranking data are also modeled using a variety of modern tools such as CART, MCMC, EM algorithm and factor analysis. This book deals with statistical methods used for analyzing such data and provides a novel and unifying approach for hypotheses testing. The techniques described in the book are illustrated with examples and the statistical software is provided on the authors’ website.

  20. Recognizing mid-career productivity: the 2008 Retrovirology Prize, call for nomination

    Directory of Open Access Journals (Sweden)

    Jeang Kuan-Teh

    2008-09-01

    Full Text Available Abstract A recent analysis suggested a narrow age range for productivity of innovative work by researchers. The Retrovirology Prize seeks to recognize the research of a mid-career retrovirologist between the ages of 45 and 60. The 2007 Retrovirology Prize was awarded to Dr. Karen Beemon. Nominations are being solicited for the 2008 prize.

  1. 77 FR 36272 - SunShot Prize: America's Most Affordable Rooftop

    Science.gov (United States)

    2012-06-18

    ...The Department of Energy (DOE) announces in this notice the release of the SunShot Prize: America's Most Affordable Rooftop Solar for public comment. Interested persons are encouraged to learn about the SunShot Prize: America's Most Affordable Rooftop rules at eere.energy.gov/solar/sunshot/prize.html.

  2. The Nobel Prize Award Ceremony 1984 at the Stockholm Concert Hall, Sweden, 10 December

    CERN Multimedia

    TV1 Fakta, Stockholm

    1984-01-01

    The Nobel Prizes in Physics, Chemistry, Physiology or Medicine and Literature as well as the Economics Prize are awarded on 10 December at the Stockholm Concert Hall in Sweden. Organized by the Nobel Foundation, the Nobel Prize Award Ceremony is the highlight of the Nobel Week celebrating the Nobel Laureates and their work.

  3. The Nobel Prize Award Ceremony 1992 at the Stockholm Concert Hall, Sweden, 10 December

    CERN Multimedia

    Eurovision / TF1

    1992-01-01

    The Nobel Prizes in Physics, Chemistry, Physiology or Medicine and Literature as well as the Economics Prize are awarded on 10 December at the Stockholm Concert Hall in Sweden. Organized by the Nobel Foundation, the Nobel Prize Award Ceremony is the highlight of the Nobel Week – celebrating the Nobel Laureates and their work.

  4. The world made by Noble prize : chemistry volume I

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-06-15

    This book contains two parts about items by chemistry. The first part introduces Alfred Bernhard Nodel, Pioneers without Nobel Prize, Garbage Bag, Non-sticky Frying Pan, Nylon Stockings, Plastic Electricity, Synthetic Dyestuff, Gin and Tonic, Soccer Ball, Fertilizer, DDT, Dentifrice, Kimchi, Makgeolli, Ice cream, Anodyne and Firefly. The second part lists PET-MRI, Color photo, Holography, Art diamond Incandescent lamp and Neon Sign, Imitation work, Alchemy, Nuclear Power plant, Synthetic Oil and Sugar, Freon gas, Water Car, Estate agency Mars, and winners of Nobel prize in physics.

  5. [Lecturing--an enduring teaching method].

    Science.gov (United States)

    Eika, Berit; Wichmann-Hansen, Gitte; Høyer, Christian S; Mørcke, Anne Mette

    2008-10-27

    Lecturing is one of the oldest forms of teaching. The lecture is as effective as other teaching formats for transmitting information. One of the major defects of the lecture method is that it tends to induce passive learning. In order to lecture effectively, the lecturer must gain and hold the attention of the audience. Also, the audience should be given a chance to elaborate on the information presented. The list of expedient lecturing skills is long. In this paper we focus on how to effectively open and close a lecture. In addition, we give suggestions to how an audience may be actively engaged.

  6. Ranking nodes in growing networks: When PageRank fails

    Science.gov (United States)

    Mariani, Manuel Sebastian; Medo, Matúš; Zhang, Yi-Cheng

    2015-11-01

    PageRank is arguably the most popular ranking algorithm which is being applied in real systems ranging from information to biological and infrastructure networks. Despite its outstanding popularity and broad use in different areas of science, the relation between the algorithm’s efficacy and properties of the network on which it acts has not yet been fully understood. We study here PageRank’s performance on a network model supported by real data, and show that realistic temporal effects make PageRank fail in individuating the most valuable nodes for a broad range of model parameters. Results on real data are in qualitative agreement with our model-based findings. This failure of PageRank reveals that the static approach to information filtering is inappropriate for a broad class of growing systems, and suggest that time-dependent algorithms that are based on the temporal linking patterns of these systems are needed to better rank the nodes.

  7. University Rankings in Critical Perspective

    Science.gov (United States)

    Pusser, Brian; Marginson, Simon

    2013-01-01

    This article addresses global postsecondary ranking systems by using critical-theoretical perspectives on power. This research suggests rankings are at once a useful lens for studying power in higher education and an important instrument for the exercise of power in service of dominant norms in global higher education. (Contains 1 table and 1…

  8. University Ranking as Social Exclusion

    Science.gov (United States)

    Amsler, Sarah S.; Bolsmann, Chris

    2012-01-01

    In this article we explore the dual role of global university rankings in the creation of a new, knowledge-identified, transnational capitalist class and in facilitating new forms of social exclusion. We examine how and why the practice of ranking universities has become widely defined by national and international organisations as an important…

  9. Exploring medical student decisions regarding attending live lectures and using recorded lectures.

    Science.gov (United States)

    Gupta, Anmol; Saks, Norma Susswein

    2013-09-01

    Student decisions about lecture attendance are based on anticipated effect on learning. Factors involved in decision-making, the use of recorded lectures and their effect on lecture attendance, all warrant investigation. This study was designed to identify factors in student decisions to attend live lectures, ways in which students use recorded lectures, and if their use affects live lecture attendance. A total of 213 first (M1) and second year (M2) medical students completed a survey about lecture attendance, and rated factors related to decisions to attend live lectures and to utilize recorded lectures. Responses were analyzed overall and by class year and gender. M1 attended a higher percentage of live lectures than M2, while both classes used the same percentage of recorded lectures. Females attended more live lectures, and used a smaller percentage of recorded lectures. The lecturer was a key in attendance decisions. Also considered were the subject and availability of other learning materials. Students use recorded lectures as replacement for live lectures and as supplement to them. Lectures, both live and recorded, are important for student learning. Decisions about lecture placement in the curriculum need to be based on course content and lecturer quality.

  10. PageRank tracker: from ranking to tracking.

    Science.gov (United States)

    Gong, Chen; Fu, Keren; Loza, Artur; Wu, Qiang; Liu, Jia; Yang, Jie

    2014-06-01

    Video object tracking is widely used in many real-world applications, and it has been extensively studied for over two decades. However, tracking robustness is still an issue in most existing methods, due to the difficulties with adaptation to environmental or target changes. In order to improve adaptability, this paper formulates the tracking process as a ranking problem, and the PageRank algorithm, which is a well-known webpage ranking algorithm used by Google, is applied. Labeled and unlabeled samples in tracking application are analogous to query webpages and the webpages to be ranked, respectively. Therefore, determining the target is equivalent to finding the unlabeled sample that is the most associated with existing labeled set. We modify the conventional PageRank algorithm in three aspects for tracking application, including graph construction, PageRank vector acquisition and target filtering. Our simulations with the use of various challenging public-domain video sequences reveal that the proposed PageRank tracker outperforms mean-shift tracker, co-tracker, semiboosting and beyond semiboosting trackers in terms of accuracy, robustness and stability.

  11. The Progressive Insurance Automotive X PRIZE Education Program

    Energy Technology Data Exchange (ETDEWEB)

    Robyn Ready

    2011-12-31

    The Progressive Insurance Automotive X PRIZE Education Program conducted education and outreach activities and used the competition's technical goals and vehicle demonstrations as a means of attracting students and the public to learn more about advanced vehicle technologies, energy efficiency, climate change, alternative fuels, and the science and math behind efficient vehicle development. The Progressive Insurance Automotive X PRIZE Education Program comprised three integrated components that were designed to educate the general public and create a multi-tiered initiative to engage students and showcase the 21st century skills students will need to compete in our global economy: teamwork, creativity, strong literacy, math and science skills, and innovative thinking. The elements included an Online Experience, a National Student Contest, and in person education events and activites. The project leveraged online connections, strategic partnerships, in-classroom, and beyond-the-classroom initiatives, as well as mainstream media. This education program supported by the U.S. Department of Energy (DOE) also funded the specification of vehicle telemetry and the full development and operation of an interactive online experience that allowed internet users to follow the Progressive Insurance Automotive X PRIZE vehicles as they performed in real-time during the Progressive Insurance Automotive X PRIZE competition events.

  12. Information and Announcements Prize for Innovation in Alternative ...

    Indian Academy of Sciences (India)

    IAS Admin

    George A Olah and G K Surya Prakash of the University of Southern California for their work on the methanol economy have been awarded the 2013 Eric and Sheila Samson Prime Minister's Prize for Innovation in Alternative Fuels for Transportation by the State of Israel. This is the first ever and the largest (US $1 million) ...

  13. Whose Big Prize? A Response to Hall and Gunter

    Science.gov (United States)

    Furlong, John

    2009-01-01

    This article presents the author's response to Hall and Gunter who accuse the author of trying to mount "a stout defence" of New Labour's reforms of the teaching profession. Hall and Gunter go further and accuse the author of "triumphalism" in his use of the title "Tony Blair's big prize". Their second and more…

  14. Supporting Military Veteran Students: Early Lessons from Kohlberg Prize Recipients

    Science.gov (United States)

    Karp, Melinda Mechur; Klempin, Serena

    2016-01-01

    Postsecondary education participation is critical for military-connected individuals as they transition back to civilian life. The Kisco Foundation's Kohlberg Prize, a competitive grant awarded in 2015 and 2016, is aimed at making community colleges more welcoming and better able to meet the needs of veteran students. This review details the early…

  15. Student Intern Lands Top Prize in National Science Competition | Poster

    Science.gov (United States)

    By Ashley DeVine, Staff Writer Student intern Sam Pritt’s interest in improving geolocation led him to develop a project that won a top regional prize at the Siemens Competition in Math, Science, and Technology in November. Pritt was awarded a $3,000 college scholarship, and he competed in the national competition in early December.

  16. Eppur Si Muove! The 2013 Nobel Prize in Chemistry

    Energy Technology Data Exchange (ETDEWEB)

    Smith, Jeremy C. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Univ. of Tennessee, Knoxville, TN (United States); Roux, Benoit [Univ. of Chicago, Chicago, IL (United States)

    2013-12-03

    The 2013 Nobel Prize in Chemistry has been awarded to Martin Karplus, Michael Levitt, and Arieh Warshel for their work on developing computational methods to study complex chemical systems. Hence, their work has led to mechanistic critical insights into chemical systems both large and small and has enabled progress in a number of different fields, including structural biology.

  17. The 2010 Chemistry Nobel Prize: Pd (0)-Catalyzed Organic Synthesis

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 16; Issue 2. The 2010 Chemistry Nobel Prize: Pd(O)-Catalyzed Organic Synthesis. Gopalpur Nagendrappa Y C Sunil Kumar. General Article Volume 16 Issue 2 February 2011 pp 152-164 ...

  18. Defining Excellence: Lessons from the 2013 Aspen Prize Finalists

    Science.gov (United States)

    Aspen Institute, 2013

    2013-01-01

    In many respects, one couldn't find a group of 10 schools more diverse than the finalists for the 2013 Aspen Prize for Community College Excellence. One community college serves 1,500 students, another 56,000. There are institutions devoted primarily--even solely--to technical degrees, and ones devoted mainly to preparing students for further…

  19. The 2013 Aspen Prize for Community College Excellence

    Science.gov (United States)

    Perlstein, Linda

    2013-01-01

    For millions of Americans, community colleges provide an essential pathway to well-paying jobs and continuing higher education. The Aspen Prize for Community College Excellence honors those institutions that strive for and achieve exceptional levels of success for all students, while they are in college and after they graduate. Community colleges…

  20. SunShot Catalyst Prize Competition Fact Sheet

    Energy Technology Data Exchange (ETDEWEB)

    Solar Energy Technologies Office

    2015-04-01

    This fact sheet is an overview of the Catalyst Energy Innovation Prize, an open innovation program launched in 2014 by the U.S. Department of Energy SunShot Initiative. This program aims to catalyze the rapid creation and development of products and solutions that address near-term challenges in the U.S. solar energy marketplace.

  1. The Competition "First Step to Nobel Prize in Physics"

    Science.gov (United States)

    Gorzkowski, W.; Surya, Y; Zuberek, R

    2011-01-01

    This paper presents the history of the competition First Step to Nobel Prize in Physics organized by Poland, its development from a national workshop in 1991/92 to an international competition nowadays and its organization, as well as the results obtained by the participants. (Contains 1 table.)

  2. Harry Smith — recipient of the 2008 Molecular Ecology Prize

    Science.gov (United States)

    Harry Smith is a scholar, mentor, internationally renowned researcher, eloquent speaker and author, pioneering journal editor and highly valued colleague who has contributed greatly in multiple ways to plant science and the community. He richly deserves the honour of the Molecular Ecology Prize....

  3. The Nobel Prize in Physiology or Medicine 2001

    Indian Academy of Sciences (India)

    The Nobel Prize in Physiology or Medicine 2001 - From Yeast Genetics to Cancer Biology. Trupti Kawli. General Article Volume 7 Issue 2 February 2002 pp 46-54 ... Author Affiliations. Trupti Kawli1. Department of Molecular Reproduction, Development and Genetics Indian Institute of Science Bangalore 560 012, India.

  4. The 2015 Nobel Prize in Physiology or Medicine

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 21; Issue 4. The 2015 Nobel Prize in Physiology or Medicine: A Soil Bacterium and a Chinese Herb Steal the Show. Pundi N Rangarajan. General Article Volume 21 Issue 4 April 2016 pp 315-326 ...

  5. ATLAS Collaboration Reaction to 2013 Physics Nobel Prize Announcement

    CERN Multimedia

    Abdeslam Hoummada

    2013-01-01

    Physicists from ATLAS took a brief time out from their collaboration week in Marrakech, Morocco to watch the announcement of the Nobel Prize in Physics for 2013. To their delight, it was awarded to Francois Englert and Peter Higgs for their pioneering work on the electroweak-symmetry-breaking mechanism in 1964.

  6. Cracker Jacks: "Finding the Prize" inside Each Adolescent Learner

    Science.gov (United States)

    Ellerbrock, Cheryl; DiCicco, Michael; Denmon, Jennifer M.; Parke, Erin; Mead, Sarah

    2017-01-01

    The purpose of this manuscript is to highlight several practical classroom examples of asset-driven acts of reciprocal care and content-driven community builders and icebreakers that highlight ways to "find the prize" inside each student by fostering an adolescent-centered community of care that is committed to both relationships and…

  7. The 1995 Nobel Prize in Physiology or Medicine

    Indian Academy of Sciences (India)

    The Nobel Prize in Biology (correctly stated, in Physiology or Medicine) for 1995 was award- ed jointly to Edward B Lewis (77 years old) of the California In~stitute of Technology,. Christiane Nusslein-Volhard (52) of the Max. Planck Institute for Developmental Biology in Tubingen and Eric Wieschaus (48) of. Princeton ...

  8. "Not Censorship but Selection": Censorship and/as Prizing

    Science.gov (United States)

    Kidd, Kenneth

    2009-01-01

    This essay calls for a fresh critical approach to the topic of censorship, suggesting that anticensorship efforts, while important and necessary, function much like literary prizing. The analysis draws especially on James English's recent study "The Economy of Prestige." There are two central arguments: first, that the librarian ethic of…

  9. Templeton Prize winner defends Christianity's credibility in a scientific age

    CERN Multimedia

    Heffern, Rich

    2002-01-01

    The 2002 Templeton Prize has gone to the Rev. John C. Polkinghome, a British mathematical physicist and Anglican priest, and a key spokesperson for belief in God in an age of science, defending the ideal that faith is not against science but inconcert with it

  10. Physics GRE Scores of Prize Postdoctoral Fellows in Astronomy

    Science.gov (United States)

    Levesque, Emily M.; Bezanson, Rachel; Tremblay, Grant

    2017-01-01

    The Physics GRE has long been a required element of the graduate admissions process in many U.S. astronomy programs; however, its predictive power and utility as a means of selection "successful" applicants had not been quantitatively examined until recently. In the fall of 2015 we circulated a short questionnaire to 271 people who have held U.S. prize postdoctoral fellowships in astrophysics between 2010-2015, asking them to report their Physics GRE scores. The response rate was 64%, and the responding sample was unbiased with respect to the overall gender distribution of prize fellows. The responses revealed that the Physics GRE scores of prize fellows do not adhere to any minimum percentile score and show no statistically significant correlation with the number of first author papers published. As an example, a Physics GRE percentile cutoff of 60% would have eliminated 44% of 2010-2015 U.S. prize postdoctoral fellows, including 60% of the female fellows. From these data, we found no evidence that the Physics GRE could be used as an effective predictor of "success" either in or beyond graduate school. Following this work and last year's official recommendation from the AAS, several astronomy departments have recently decided to eliminate the Physics GRE as a requirement for graduate applicants.

  11. The 2001 Nobel Prize in Physics-Bose–Einstein Condensation

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 7; Issue 1. The 2001 Nobel Prize in Physics - Bose–Einstein Condensation. Vasant Natarajan. General Article Volume 7 Issue 1 January 2002 pp 23-30. Fulltext. Click here to view fulltext PDF. Permanent link:

  12. Physics Nobel Prize 2000 goes to Semiconductor Pioneers

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 6; Issue 1. Physics Nobel Prize 2000 goes to Semiconductor Pioneers. V Venkataraman. Research News Volume 6 Issue 1 January 2001 pp 79-83. Fulltext. Click here to view fulltext PDF. Permanent link:

  13. The Ribosome and the 2009 Nobel Prize in Chemistry

    Indian Academy of Sciences (India)

    Permanent link: http://www.ias.ac.in/article/fulltext/reso/015/06/0526-0537. Keywords. Protein synthesis; tRNA; mRNA; decoding; peptide bond formation; antibiotic resistance; Nobel Prize in Chemistry 2009. Author Affiliations. Laasya Samhita1 Umesh Varshney1. Department of Microbiology and Cell Biology, Indian Institute ...

  14. Message by Fabiola Gianotti on receipt of Tomassoni Prize 2017

    CERN Multimedia

    2017-01-01

    Thank you message by Fabiola Gianotti on the award of the 2017 Tomassoni Prize to her with the following motivation "For the innumerable contributions to particle physics, that led her to play a leading role in discovering the Higgs boson as spokesperson of the ATLAS experiment and in the orientation of current and future research as Director General of CERN.”

  15. Giving Back — IDRC photo contest winner shares prize with ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    The winner of IDRC's “Expose Urban Solutions” photo contest, Baker shared his CA$2 500 prize with the two people who made his photo possible. ... exhibition booth at WUF3 — the week-long third World Urban Forum held in Vancouver in June 2006 which drew some 10 000 participants to debate the potentials and perils ...

  16. How Robert A. Millikan Got the Physics Nobel Prize

    Science.gov (United States)

    Panusch, Martin; Heering, Peter; Singh, Rajinder

    2010-01-01

    In 1923, R.A. Millikan was awarded the Nobel Prize in Physics for his work on the elementary charge of electricity and on the photoelectric effect. Recently, historical research had a focus on Millikan's publication practice, as well as on the role of his assistant, Harvey Fletcher. Several studies have raised doubts on whether Millikan can…

  17. Tight Focus on Instruction Wins Texas District Prize

    Science.gov (United States)

    Maxwell, Lesli A.

    2009-01-01

    It took a while for four-time finalist Aldine, Texas, to win the Broad Prize for Urban Education. But it took even longer to craft the system that ultimately put the district over the top. Educators in Aldine district have been working for more than a decade to refine their "managed instruction" system. Reviewers examined how the school…

  18. Reclaiming "Lost Prizes": An Interview with Ken McCluskey

    Science.gov (United States)

    Van Bockern, Steve

    2012-01-01

    This article presents an interview with Dr. Ken McCluskey, Dean and Professor of Education at the University of Winnipeg. He is known internationally for his work in several areas including: (1) mentoring; (2) attention-deficit hyperactivity disorder; (3) at-risk children and youth (where his "Lost Prizes" and related projects serve as…

  19. Modular Curriculum: English, American Nobel Prize Winners in Literature.

    Science.gov (United States)

    Phillips, James A.

    This independent study module treats those Americans who have been awarded the Nobel Prize in Literature. They include Sinclair Lewis, Eugene O'Neill, T. S. Eliot, William Faulkner, Ernest Hemingway, John Steinbeck, and Pearl Buck. Selections from the writings of these authors are included. Their works represent many literary genres and also…

  20. Pennies from heaven? Conceptions and earmarking of lottery prize money.

    Science.gov (United States)

    Hedenus, Anna

    2014-06-01

    The source of money has been shown to be important for how money is spent. In addition, sudden wealth is often associated with social and psychological risks. This article investigates if conceptions of lottery prize money--as a special kind of money--imply restrictions on how it can be spent. Analysis of interviews with lottery winners shows that interviewees use earmarking of the prize money as a strategy for avoiding the pitfalls associated with a lottery win. Conceptions of lottery prize money as 'a lot' or as 'a little', as shared or personal, and as an opportunity or a risk, influences the ends for which it is earmarked: for self-serving spending, a 'normal' living standard, paying off loans, saving for designated purposes, or for economic security and independence. Clearly defining and earmarking lottery prize money thus helps lottery winners construe their sudden wealth, not as a risk, but as 'pennies from heaven.' © London School of Economics and Political Science 2014.

  1. Berners-Lee wins inaugural Millennium Technology prize

    CERN Multimedia

    2004-01-01

    "World Wide Web inventor Tim Berners-Lee today was named recipient of the first-ever Millennium Technology Prize. The honor, which is accompanied by one million euros, is bestowed by the Finnish Technology Award Foundation as an international acknowledgement of outstanding technological innovation aimed at promoting quality of life and sustainable economic and societal development" (1 page)

  2. Computer science students win grand prize for 3-D competition

    OpenAIRE

    Mackay, Steven D.

    2010-01-01

    A group of doctoral students in the Virginia Tech College of Engineering's computer science department, led by associate professor Doug Bowman, recently won first place in the 3-D UI Grand Prize competition at the 2010 Institute of Electrical and Electronics Engineers (IEEE) Symposium on 3-D User Interfaces.

  3. Former IDRC grantee Daniel Hillel wins World Food Prize | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2016-05-26

    May 26, 2016 ... Daniel Hillel, who pioneered an innovative way of bringing water to crops in arid and dry-land regions, was named the winner of the 2012 World Food Prize. The announcement was made in Washington where US Secretary of State Hillary Clinton described Hillel as understanding "the critical role water ...

  4. Practical strategies for effective lectures.

    Science.gov (United States)

    Lenz, Peter H; McCallister, Jennifer W; Luks, Andrew M; Le, Tao T; Fessler, Henry E

    2015-04-01

    Lecturing is an essential teaching skill for scientists and health care professionals in pulmonary, critical care, and sleep medicine. However, few medical or scientific educators have received training in contemporary techniques or technology for large audience presentation. Interactive lecturing outperforms traditional, passive-style lecturing in educational outcomes, and is being increasingly incorporated into large group presentations. Evidence-based techniques range from the very simple, such as inserting pauses for audience discussion, to more technologically advanced approaches such as electronic audience response systems. Alternative software platforms such as Prezi can overcome some of the visual limits that the ubiquitous PowerPoint imposes on complex scientific narratives, and newer technology formats can help foster the interactive learning environment. Regardless of the technology, adherence to good principles of instructional design, multimedia learning, visualization of quantitative data, and informational public speaking can improve any lecture. The storyline must be clear, logical, and simplified compared with how it might be prepared for scientific publication. Succinct outline and summary slides can provide a roadmap for the audience. Changes of pace, and summaries or other cognitive breaks inserted every 15-20 minutes can renew attention. Graphics that emphasize clear, digestible data graphs or images over tables, and simple, focused tables over text slides, are more readily absorbed. Text slides should minimize words, using simple fonts in colors that contrast to a plain background. Adherence to these well-established principles and addition of some new approaches and technologies will yield an engaging lecture worth attending.

  5. Religiosity and value system of young lecturers: qualitative research data

    Directory of Open Access Journals (Sweden)

    Pavenkov Oleg Vladimirovich

    2016-12-01

    Full Text Available This article analyses the Orthodox religion as a factor of formation of spiritual and value system of young teachers. Young lecturers belong to the socio-demographic group of 20 to 35 years involved mainly in teaching and research activities. The article presents the results of a qualitative study of value system of 23 informants. The study showed that the system of values of informants is characterized by syncretism. Almost all the informants are religious, but religiosity is differently ranked in their value system. Religiosity is often in a latent form.

  6. CFN lectures on functional nanostructures

    CERN Document Server

    Vojta, Matthias; Schön, Gerd

    2011-01-01

    This series of books contains selected and edited lectures from summer schools organized by the Center for Functional nanostructures (C.F.N.) at the University of Karlsruhe. The mission of the C.F.N. is to carry out research in the following areas: nanophotonics, nanoelectronics, molecular nanostructures and nanostructured materials. The aim of the summer schools is mainly to exchange new ideas and illustrate emerging research methodologies through a series of topical, introductory lectures. This is reflected by both the selection of topics addressed in the present volume, nanoelectronics, as well as the tutorial aspect of the contributions.

  7. PageRank of integers

    Science.gov (United States)

    Frahm, K. M.; Chepelianskii, A. D.; Shepelyansky, D. L.

    2012-10-01

    We up a directed network tracing links from a given integer to its divisors and analyze the properties of the Google matrix of this network. The PageRank vector of this matrix is computed numerically and it is shown that its probability is approximately inversely proportional to the PageRank index thus being similar to the Zipf law and the dependence established for the World Wide Web. The spectrum of the Google matrix of integers is characterized by a large gap and a relatively small number of nonzero eigenvalues. A simple semi-analytical expression for the PageRank of integers is derived that allows us to find this vector for matrices of billion size. This network provides a new PageRank order of integers.

  8. Ranking in evolving complex networks

    Science.gov (United States)

    Liao, Hao; Mariani, Manuel Sebastian; Medo, Matúš; Zhang, Yi-Cheng; Zhou, Ming-Yang

    2017-05-01

    Complex networks have emerged as a simple yet powerful framework to represent and analyze a wide range of complex systems. The problem of ranking the nodes and the edges in complex networks is critical for a broad range of real-world problems because it affects how we access online information and products, how success and talent are evaluated in human activities, and how scarce resources are allocated by companies and policymakers, among others. This calls for a deep understanding of how existing ranking algorithms perform, and which are their possible biases that may impair their effectiveness. Many popular ranking algorithms (such as Google's PageRank) are static in nature and, as a consequence, they exhibit important shortcomings when applied to real networks that rapidly evolve in time. At the same time, recent advances in the understanding and modeling of evolving networks have enabled the development of a wide and diverse range of ranking algorithms that take the temporal dimension into account. The aim of this review is to survey the existing ranking algorithms, both static and time-aware, and their applications to evolving networks. We emphasize both the impact of network evolution on well-established static algorithms and the benefits from including the temporal dimension for tasks such as prediction of network traffic, prediction of future links, and identification of significant nodes.

  9. BACTERIAL BIOFILMS AND INFECTION (LECTURE

    Directory of Open Access Journals (Sweden)

    Chernjavsky VI

    2013-03-01

    Full Text Available The lecture presents published data on the biofilm – a special from of organization of the microflora of the human body, the role of microbial biofilms in the genesis and development of many common diseases. Different mechanisms of antimicrobial resistance development in biofilm are reviewed in the article

  10. Tata lectures on overlap fermions

    CERN Document Server

    Narayanan, R

    2011-01-01

    Overlap formalism deals with the construction of chiral gauge theories on the lattice. These set of lectures provide a pedagogical introduction to the subject with emphasis on chiral anomalies and gauge field topology. Subtleties associated with the generating functional for gauge theories coupled to chiral fermions are discussed.

  11. Lectures on algebraic model theory

    CERN Document Server

    Hart, Bradd

    2001-01-01

    In recent years, model theory has had remarkable success in solving important problems as well as in shedding new light on our understanding of them. The three lectures collected here present recent developments in three such areas: Anand Pillay on differential fields, Patrick Speissegger on o-minimality and Matthias Clasen and Matthew Valeriote on tame congruence theory.

  12. The Oskar Klein memorial lectures

    CERN Document Server

    Bergström, Lars

    1991-01-01

    This is an invaluable collection of colloquium-type lectures given by some of the most prominent theoretical physicists of today. In a form accessible to the interested general physicist, it covers topics ranging from the use of field-theoretical methods in different contexts via duality symmetries between various field theories, to the Ads/CFT correspondence and cosmology.

  13. Teaching Idioms: Video or Lecture.

    Science.gov (United States)

    Kenyon, Patricia; Daly, Kimberly

    1991-01-01

    A study evaluated the effectiveness of video instruction in teaching the meanings and uses of idioms to 20 deaf adolescents. Students improved their knowledge and use of idioms more when exposed to the video/discussion approach than to the lecture/discussion approach. (DB)

  14. Applied Fluid Mechanics. Lecture Notes.

    Science.gov (United States)

    Gregg, Newton D.

    This set of lecture notes is used as a supplemental text for the teaching of fluid dynamics, as one component of a thermodynamics course for engineering technologists. The major text for the course covered basic fluids concepts such as pressure, mass flow, and specific weight. The objective of this document was to present additional fluids…

  15. Public Lecture: The Odyssey of Voyager

    CERN Multimedia

    CERN. Geneva

    2015-01-01

    Should you wish to attend to this lecture only (and not the full colloquium), please register here: https://indico.cern.ch/event/387001/registration/ Participants to the full colloquium are automatically registered to the public lectures.

  16. RANK and RANK ligand expression in primary human osteosarcoma

    Directory of Open Access Journals (Sweden)

    Daniel Branstetter

    2015-09-01

    Our results demonstrate RANKL expression was observed in the tumor element in 68% of human OS using IHC. However, the staining intensity was relatively low and only 37% (29/79 of samples exhibited≥10% RANKL positive tumor cells. RANK expression was not observed in OS tumor cells. In contrast, RANK expression was clearly observed in other cells within OS samples, including the myeloid osteoclast precursor compartment, osteoclasts and in giant osteoclast cells. The intensity and frequency of RANKL and RANK staining in OS samples were substantially less than that observed in GCTB samples. The observation that RANKL is expressed in OS cells themselves suggests that these tumors may mediate an osteoclastic response, and anti-RANKL therapy may potentially be protective against bone pathologies in OS. However, the absence of RANK expression in primary human OS cells suggests that any autocrine RANKL/RANK signaling in human OS tumor cells is not operative, and anti-RANKL therapy would not directly affect the tumor.

  17. Ranking structures and Rank-Rank Correlations of Countries. The FIFA and UEFA cases

    CERN Document Server

    Ausloos, Marcel; Gadomski, Adam; Vitanov, Nikolay K

    2014-01-01

    Ranking of agents competing with each other in complex systems may lead to paradoxes according to the pre-chosen different measures. A discussion is presented on such rank-rank, similar or not, correlations based on the case of European countries ranked by UEFA and FIFA from different soccer competitions. The first question to be answered is whether an empirical and simple law is obtained for such (self-) organizations of complex sociological systems with such different measuring schemes. It is found that the power law form is not the best description contrary to many modern expectations. The stretched exponential is much more adequate. Moreover, it is found that the measuring rules lead to some inner structures, in both cases.

  18. Ranking structures and rank-rank correlations of countries: The FIFA and UEFA cases

    Science.gov (United States)

    Ausloos, Marcel; Cloots, Rudi; Gadomski, Adam; Vitanov, Nikolay K.

    2014-04-01

    Ranking of agents competing with each other in complex systems may lead to paradoxes according to the pre-chosen different measures. A discussion is presented on such rank-rank, similar or not, correlations based on the case of European countries ranked by UEFA and FIFA from different soccer competitions. The first question to be answered is whether an empirical and simple law is obtained for such (self-) organizations of complex sociological systems with such different measuring schemes. It is found that the power law form is not the best description contrary to many modern expectations. The stretched exponential is much more adequate. Moreover, it is found that the measuring rules lead to some inner structures in both cases.

  19. How We Think and Learn. Lecture Series.

    Science.gov (United States)

    National Learning Center, Washington, DC.

    A lecture series was conducted in 1989 to present information on learning theories by learning theorists. This document contains short texts of the lectures; full texts are available on request. In lecture 1, Robert Chase discusses educational reform and Bonnie Guiton examines educational goals from the perspective of White House policy. In…

  20. The Lecture-Discussion Format Revisited.

    Science.gov (United States)

    Bowman, James S.

    1979-01-01

    A new look at the standard lecture/discussion format for the large introductory college course is offered, along with suggestions to upgrade its quality. Foci for improvement include organization of lecture material, teacher-student interaction, lecture delivery, feedback, discussion group supervision, and course evaluation. (JMD)

  1. Tim Berners-Lee receives the Millennium Technology Prize

    CERN Multimedia

    2004-01-01

    On 15 April, for his invention of the Web, Tim Berners-Lee was awarded the first ever Millennium Technology Prize by the Finnish Technology Award Foundation, which recognises technological innovations of lasting benefit to society. "Tim Berners-Lee's invention perfectly encapsulates the spirit of the Prize. The Web is encouraging new types of social networks, contributing to transparency and democracy, and opening up new avenues for information management and business development," underlined Pekka Tarjanne, chairman of the jury and former Secretary-General of the International Telecommunication Union (ITU). Tim Berners-Lee is congratulated by Jukka Valtasaari, Finland's Ambassador to the United States. Tim Berners-Lee created the first server, browser and editor, the HTML code, the URL address and the HTTP transmission protocol at CERN in 1990. CERN released the Web into the public domain in 1993. Tim Berners-Lee is currently head of the World Wide Web Consortium, managed by ERCIM (Europe...

  2. Nobel Prize winner visits CERN’s superconductors

    CERN Multimedia

    2008-01-01

    On Wednesday 23 April Georg Bednorz, who won the Nobel Prize for physics in 1987, visited CERN along with 44 of his colleagues from the IBM Zurich Research Laboratory. Georg Bednorz (second from right) with colleagues from the IBM Zurich Research Laboratory in the LHC tunnel. On their arrival, Jos Engelen, the Chief Scientific Officer, gave the IBM group an introduction to CERN. Bednorz came to CERN only recently for the Open Days to give a seminar, but unfortunately did not have time to visit the experiments, so this trip was organised instead. Along with Alex Müller, Bednorz was awarded the Noble Prize for his discovery of superconductivity for the so-called high temperature superconductors, essentially copper-oxide-based compounds showing superconductivity at temperatures much higher than had previously been thought possible. The LHC magnets are built with low-temperature superconductors but many current leads that supply power to the LHC cryostats are made with...

  3. Pierre Darriulat is awarded the André Lagarrigue Prize

    CERN Multimedia

    2009-01-01

    Pierre Darriulat at the VATLY Laboratory in Hanoï. Former CERN Research Director, Pierre Darriulat, who is now Professor of Physics at VATLY in Hanoi (Vietnam), has won the 2008 André Lagarrigue Prize. This prize, instituted by the Linear Accelerator Laboratory (LAL) at Orsay under the aegis of the French Physical Society, is awarded to front-line researchers who have had responsibility for machine/detector construction and derived maximum scientific benefit from such projects, performed in a French laboratory or in close collaboration with French groups. Pierre Darriulat has received the award in recognition of his outstanding career at the CEA, at LBL (Berkeley) and at CERN from 1964 onwards. At CERN he managed the experiments at the Intersecting Storage Rings (ISR) before taking charge of the UA2 collaboration from 1980 to 1986, which participated in decisive discoveries at the ppbar collider. In particular, in 1982, the UA2 experiment began observing high trans...

  4. How citation boosts promote scientific paradigm shifts and Nobel Prizes

    CERN Document Server

    Mazloumian, Amin; Helbing, Dirk; Lozano, Sergi; Fortunato, Santo; 10.1371/journal.pone.0018975

    2011-01-01

    Nobel Prizes are commonly seen to be among the most prestigious achievements of our times. Based on mining several million citations, we quantitatively analyze the processes driving paradigm shifts in science. We find that groundbreaking discoveries of Nobel Prize Laureates and other famous scientists are not only acknowledged by many citations of their landmark papers. Surprisingly, they also boost the citation rates of their previous publications. Given that innovations must outcompete the rich-gets-richer effect for scientific citations, it turns out that they can make their way only through citation cascades. A quantitative analysis reveals how and why they happen. Science appears to behave like a self-organized critical system, in which citation cascades of all sizes occur, from continuous scientific progress all the way up to scientific revolutions, which change the way we see our world. Measuring the "boosting effect" of landmark papers, our analysis reveals how new ideas and new players can make their...

  5. 2014 Nuclear Fusion Prize Acceptance Speech 2014 Nuclear Fusion Prize Acceptance Speech

    Science.gov (United States)

    Snyder, P. B.

    2015-01-01

    It is a great honor to receive the 2014 Nuclear Fusion Prize, here at the 25th IAEA Fusion Energy Conference. On behalf of everyone involved in this work, I would like to thank the IAEA, the Nuclear Fusion journal team, the IOP, and specifically Mitsuru Kikuchi, for their support of this important award. I would also like to acknowledge the many important contributions made by the other ten papers nominated for this prize. Our paper investigates the physics of the H-mode pedestal in tokamaks, specifically the development of a predictive understanding of the pedestal structure based on electromagnetic instabilities which constrain it, and the testing of the resulting theoretical model (EPED) against detailed observations on multiple devices. In addition to making pedestal predictions for existing devices, the paper also presents predictions for ITER, including methods for optimizing its pedestal height and fusion performance. What made this work possible, and indeed a pleasure to be involved with, was an extensive set of collaborations, including theory-experiment, multi-institutional, and international collaborations. Many of these collaborations have gone on for over a decade, and have been fostered in part by the ITPA Pedestal Group. The eight authors of this paper, from five institutions, all made important contributions. Rich Groebner, Tom Osborne and Tony Leonard carried out dedicated experiments and data analysis on the DIII-D tokamak, testing the EPED model over a very wide range of parameters. Jerry Hughes led dedicated experiments on Alcator C-Mod which tested the model at high magnetic field and pedestal pressure. Marc Beurskens carried out experiments and data analysis on the JET tokamak, testing the model at large scale. Xueqiao Xu conducted two-fluid studies of diamagnetic stabilization, which enabled a more accurate treatment of this important effect. Finally, Howard Wilson and I have been working together for many years to develop analytic formalism

  6. University Ranking Systems; Criteria and Critiques

    OpenAIRE

    Saka, Yavuz; YAMAN, Süleyman

    2011-01-01

    The purpose of this paper is to explore international university ranking systems. As a compilation study this paper provides specific criteria that each ranking system uses and main critiques regarding these ranking systems. Since there are many ranking systems in this area of research, this study focused on only most cited and referred ranking systems. As there is no consensus in terms of the criteria that these systems use, this paper has no intention of identifying the best ranking system ...

  7. "Highly qualified loser"? Harvey Cushing and the Nobel Prize.

    Science.gov (United States)

    Hansson, Nils; Schlich, Thomas

    2015-04-01

    Neurosurgery, in particular surgery of the brain, was recognized as one of the most spectacular transgressions of the traditional limits of surgical work. With their audacious, technically demanding, laboratory-based, and highly promising new interventions, prominent neurosurgeons were primary candidates for the Nobel Prize. Accordingly, neurosurgical pioneers such as Victor Horsley and, in particular, Harvey Cushing continued to be nominated for the prize. However, only António Egas Moniz was eventually awarded the prestigious award in 1949 for the introduction of frontal lobotomy, an intervention that would no longer be prize-worthy from today's perspective. Horsley and Cushing, who were arguably the most important proponents of early neurosurgery, remained "highly qualified losers," as such cases have been called. This paper examines the nominations, reviews, and discussions kept in the Nobel Archives to understand the reasons for this remarkable choice. At a more general level, the authors use the example of neurosurgery to explore the mechanisms of scientific recognition and what could be called the enacting of excellence in science and medicine.

  8. Nobel prize-winner Heinrich Rohrer visits CERN

    CERN Multimedia

    2008-01-01

    The Nobel prize-winner Heinrich Rohrer met young scientists on a recent visit to the Laboratory. From left to right: Xavier Gréhant (CERN Openlab), Ewa Stanecka (ATLAS), Magda Kowalska (ISOLDE), Heinrich Rohrer, Stéphanie Beauceron (CMS) and Ana Gago Da Silva (UNOSAT).Heinrich Rohrer, who shared the 1986 Nobel prize for physics with Gerd Binnig for the design of the scanning tunnelling microscope, visited CERN on 25 June. Welcomed by the Director-General, Robert Aymar, he visited the ATLAS cavern and control room, the Computer Centre, the Unosat project, the Antimatter Decelerator and ISOLDE. At the end of his visit, he voiced his admiration for CERN and its personnel. As a renowned Nobel prize-winner Heinrich Rohrer has the opportunity to pass on his experience and enthusiasm to young scientists. During the evening meal, at which he met five young physicists and computer scientists, who were delighted with the chance to talk to him, he stressed the importance for re...

  9. Use of a simulation of the ventilator-patient interaction as an active learning exercise: comparison with traditional lecture.

    Science.gov (United States)

    Keegan, Robert D; Brown, Gary R; Gordon, Aifang

    2012-01-01

    Research suggests that simulation technology has potential to enhance student achievement, particularly for students having a preference for hands-on learning. The aim of this study was to compare ventilation learning outcomes in students attending traditional lecture versus students using an active learning ventilation simulation. A computer simulation was developed to advance students' learning of mechanical ventilation. Forty-one students were divided into upper and lower strata based on performance rankings and were then randomly assigned to first complete a simulation scenario or view a lecture. Two distinct ventilation topics, controls and clinical, were developed for each instructional method. Students completed examinations three weeks following each respective instructional intervention (lecture or simulation scenarios) as well as one long-term examination and survey six weeks following the second examination. Upper-ranking students who learned the clinical topic through the simulation scenarios outperformed students who learned by traditional lecture. In addition, upper-ranking students scored higher than lower-ranking students in both the clinical and long-term composite examinations. No differences in student scores attributed to instructional method or class rank were identified for the controls topic. Survey results indicated that students were more engaged as learners when using the simulation and wished to have the simulation available during their clinical intensive care unit (ICU) rotations. Use of the simulation was associated with improved performance of upper-ranking students on the clinical-topic exam and was equivalent to lecture as an instructional intervention on the controls-topic exam. The simulation was perceived as an engaging, desirable tool providing immediate feedback.

  10. Integrated lecturing within clerkship course, a new learning method in nurse-anesthesia teaching

    Directory of Open Access Journals (Sweden)

    Mahmood Akhlaghi

    2015-06-01

    Full Text Available Background and purpose: Traditional lecture-based teaching has been long used to transit theoretical knowledge to the participants. Due to some problems of this didactic approach, some believe that integration within an active method is more valuable in nursing education. In this study, we hypothesized that integrating lecture-based teaching within clerkship course would enhance nurse-anesthesia students’ knowledge.Methods: A prospective randomized study was conducted. Twenty four students of two-year nurse-anesthesia participated in the study. All of the students received either didactic lectures or integrated lectures within clerkship course during a four-month semester of their educational curriculum. Their knowledge of anesthesia course was assessed at the end of the course using Wilcoxon Rank test.Results: The integrated method improved students’ final scores at the end of the semester (p=0.004. Moreover, their scores was much better when taxonomy-2 questions were compared (p=0.001.Conclusion: Incorporating didactic lecture within anesthesia clerkship course improves participants’ knowledge of anesthesia course.Keywords:  Anesthesia, Lecture, Knowledge, Anesthesia course, Clerkship course

  11. [The 69th Congress-urologists nominated for the Nobel Prize : Not everyone got a prize: four biographical sketches].

    Science.gov (United States)

    Moll, F H; Halling, T; Krischel, M; Hansson, N; Fangerau, H

    2017-09-01

    Our research group has reconstructed why the board certified urologists Werner Forssmann (1904-1979) and Charles Huggins (1901-1997) received the Nobel Prize in physiology or medicine (1956, and 1966, respectively). But the history of "Urology and the Nobel Prize" is in fact more multifaceted than the success stories of these two laureates suggest. James Israel (1848-1926), Berlin, Félix Guyon (1831-1920), Paris, Peter J. Freyer (1852-1921), London and Edwin Beer (1876-1938), New York were nominated for the award during the first three decades of the 20th century. Their candidacies mirror trends among leading urologists during the time when urology became a specialty in its own right.

  12. Ranking species in mutualistic networks.

    Science.gov (United States)

    Domínguez-García, Virginia; Muñoz, Miguel A

    2015-02-02

    Understanding the architectural subtleties of ecological networks, believed to confer them enhanced stability and robustness, is a subject of outmost relevance. Mutualistic interactions have been profusely studied and their corresponding bipartite networks, such as plant-pollinator networks, have been reported to exhibit a characteristic "nested" structure. Assessing the importance of any given species in mutualistic networks is a key task when evaluating extinction risks and possible cascade effects. Inspired in a recently introduced algorithm--similar in spirit to Google's PageRank but with a built-in non-linearity--here we propose a method which--by exploiting their nested architecture--allows us to derive a sound ranking of species importance in mutualistic networks. This method clearly outperforms other existing ranking schemes and can become very useful for ecosystem management and biodiversity preservation, where decisions on what aspects of ecosystems to explicitly protect need to be made.

  13. University rankings in computer science

    DEFF Research Database (Denmark)

    Ehret, Philip; Zuccala, Alesia Ann; Gipp, Bela

    2017-01-01

    This is a research-in-progress paper concerning two types of institutional rankings, the Leiden and QS World ranking, and their relationship to a list of universities’ ‘geo-based’ impact scores, and Computing Research and Education Conference (CORE) participation scores in the field of computer...... science. A ‘geo-based’ impact measure examines the geographical distribution of incoming citations to a particular university’s journal articles for a specific period of time. It takes into account both the number of citations and the geographical variability in these citations. The CORE participation...... score is calculated on the basis of the number of weighted proceedings papers that a university has contributed to either an A*, A, B, or C conference as ranked by the Computing Research and Education Association of Australasia. In addition to calculating the correlations between the distinct university...

  14. Performance in the Duke–Elder ophthalmology undergraduate prize examination and future careers in ophthalmology

    Science.gov (United States)

    Joshi, L; Shanmuganathan, V A; Kneebone, R L; Amoaku, W

    2011-01-01

    Aims Cognitive factors (eg, academic achievement) have had a significant role in selecting postgraduate surgical trainees in the past. This project sought to determine the role of a national undergraduate ophthalmology prize examination (Duke–Elder examination) in the selection of postgraduate ophthalmology trainees. This would also serve as a quality assurance exercise for the assessment, in which the ultimate aim is to encourage trainees into ophthalmology. Methods A retrospective analysis of the top 20 ranked candidates in the Duke–Elder examination from 1989 to 2005 (except 1995) was carried out to determine which of them subsequently entered the ophthalmic training and General Medical Council Specialist Registers. Results Out of the top 20 candidates in the exam, 29.5% went into specialist training in ophthalmology. Some appeared in the top 20 more than once, with 56% of them going into ophthalmic training, but they had a similar median time to enter training as those who appeared in the top 20 once. There was no significant evidence to suggest that the overall median ranking scores between the UK medical schools differed (P=0.23; Kruskal–Wallis test). However, there was a marked difference in frequency of top 20 candidates from each medical school, which could not be explained by the size of the medical school alone. Conclusion It is difficult to conclude from these findings the importance that the Duke–Elder examination has in the selection of trainees into ophthalmology. The role of cognitive factors in selection into postgraduate medical/surgical training is discussed, along with the potential academic criteria, which may influence interview scores. PMID:21587276

  15. Lectures on matrix field theory

    CERN Document Server

    Ydri, Badis

    2017-01-01

    These lecture notes provide a systematic introduction to matrix models of quantum field theories with non-commutative and fuzzy geometries. The book initially focuses on the matrix formulation of non-commutative and fuzzy spaces, followed by a description of the non-perturbative treatment of the corresponding field theories. As an example, the phase structure of non-commutative phi-four theory is treated in great detail, with a separate chapter on the multitrace approach. The last chapter offers a general introduction to non-commutative gauge theories, while two appendices round out the text. Primarily written as a self-study guide for postgraduate students – with the aim of pedagogically introducing them to key analytical and numerical tools, as well as useful physical models in applications – these lecture notes will also benefit experienced researchers by providing a reference guide to the fundamentals of non-commutative field theory with an emphasis on matrix models and fuzzy geometries.

  16. La lecture par le jeu

    OpenAIRE

    Gaudin Roy, Marion; Tièche Christinat, Chantal

    2012-01-01

    En tant que maîtresse de classe développement itinérante, je me suis demandé s’il était possible d’apprendre la lecture en jouant. Puis d’autre questions ont suivi : qu’est-ce que la lecture ? Qu’est-ce que le jeu ? Le jeu est perçu comme un loisir voire comme une activité oisive. Il est donc en opposition à l’apprentissage qui est perçu comme difficile et demandant des efforts. Comment se situer en tant qu’enseignante ? A travers ce mémoire, j’ai pu répondre à ces interrogations. Pour...

  17. Student perceptions of gamified audience response system interactions in large group lectures and via lecture capture technology.

    Science.gov (United States)

    Pettit, Robin K; McCoy, Lise; Kinney, Marjorie; Schwartz, Frederic N

    2015-05-22

    Higher education students have positive attitudes about the use of audience response systems (ARS), but even technology-enhanced lessons can become tiresome if the pedagogical approach is exactly the same with each implementation. Gamification is the notion that gaming mechanics can be applied to routine activities. In this study, TurningPoint (TP) ARS interactions were gamified and implemented in 22 large group medical microbiology lectures throughout an integrated year 1 osteopathic medical school curriculum. A 32-item questionnaire was used to measure students' perceptions of the gamified TP interactions at the end of their first year. The survey instrument generated both Likert scale and open-ended response data that addressed game design and variety, engagement and learning features, use of TP questions after class, and any value of lecture capture technology for reviewing these interactive presentations. The Chi Square Test was used to analyze grouped responses to Likert scale questions. Responses to open-ended prompts were categorized using open-coding. Ninety-one students out of 106 (86 %) responded to the survey. A significant majority of the respondents agreed or strongly agreed that the games were engaging, and an effective learning tool. The questionnaire investigated the degree to which specific features of these interactions were engaging (nine items) and promoted learning (seven items). The most highly ranked engagement aspects were peer competition and focus on the activity (tied for highest ranking), and the most highly ranked learning aspect was applying theoretical knowledge to clinical scenarios. Another notable item was the variety of interactions, which ranked in the top three in both the engagement and learning categories. Open-ended comments shed light on how students use TP questions for exam preparation, and revealed engaging and non-engaging attributes of these interactive sessions for students who review them via lecture capture

  18. Lecture Notes in Lie Groups

    OpenAIRE

    Ivancevic, Vladimir G.; Ivancevic, Tijana T.

    2011-01-01

    These lecture notes in Lie Groups are designed for a 1--semester third year or graduate course in mathematics, physics, engineering, chemistry or biology. This landmark theory of the 20th Century mathematics and physics gives a rigorous foundation to modern dynamics, as well as field and gauge theories in physics, engineering and biomechanics. We give both physical and medical examples of Lie groups. The only necessary background for comprehensive reading of these notes are advanced calculus ...

  19. Lectures in Complex Systems (1991)

    Science.gov (United States)

    1992-08-05

    Grossberg, S., and J. Pepe. "Schizophrenia: Possible Dependence of Associ- ational Span, Bowing, and Primacy vs. Recency on Spiking Threshold." Be...Parameters, Broken Symmetry, and Topology James P. Sethna 243 Meissner Effects and Constraints James P. Sethna 267 1991 Lectures in Complex Systems, SR...two eyes segregate from each other to form layers or columns? The first clues came from the pioneering studies of Hubel and Wiesel on the effects of

  20. Video of Christian Skau and Martin Raussen's interview with the Abel Prize Winner John Milnor

    DEFF Research Database (Denmark)

    Skau, Christian

    2011-01-01

    The television interview with Abel Laureate John Milnor that was broadcasted on Norwegian television in June is now available on the Abel Prize multimedia page. John Milnor received the Abel Prize «for pioneering discoveries in topology, geometry and algebra» to quote the Abel Committee. King...... Harald presented the Abel Prize to John Milnor at the award ceremony in Oslo, Norway on 24 May. Before the interview there is a short presentation of the award ceremony. John Milnor is interviewed by Martin Raussen and Christian Skau. The Abel Prize that carries a cash award of NOK 6 million (about EUR...

  1. Rank distributions: Frequency vs. magnitude.

    Science.gov (United States)

    Velarde, Carlos; Robledo, Alberto

    2017-01-01

    We examine the relationship between two different types of ranked data, frequencies and magnitudes. We consider data that can be sorted out either way, through numbers of occurrences or size of the measures, as it is the case, say, of moon craters, earthquakes, billionaires, etc. We indicate that these two types of distributions are functional inverses of each other, and specify this link, first in terms of the assumed parent probability distribution that generates the data samples, and then in terms of an analog (deterministic) nonlinear iterated map that reproduces them. For the particular case of hyperbolic decay with rank the distributions are identical, that is, the classical Zipf plot, a pure power law. But their difference is largest when one displays logarithmic decay and its counterpart shows the inverse exponential decay, as it is the case of Benford law, or viceversa. For all intermediate decay rates generic differences appear not only between the power-law exponents for the midway rank decline but also for small and large rank. We extend the theoretical framework to include thermodynamic and statistical-mechanical concepts, such as entropies and configuration.

  2. Rankings Methodology Hurts Public Institutions

    Science.gov (United States)

    Van Der Werf, Martin

    2007-01-01

    In the 1980s, when the "U.S. News & World Report" rankings of colleges were based solely on reputation, the nation's public universities were well represented at the top. However, as soon as the magazine began including its "measures of excellence," statistics intended to define quality, public universities nearly disappeared from the top. As the…

  3. Let Us Rank Journalism Programs

    Science.gov (United States)

    Weber, Joseph

    2014-01-01

    Unlike law, business, and medical schools, as well as universities in general, journalism schools and journalism programs have rarely been ranked. Publishers such as "U.S. News & World Report," "Forbes," "Bloomberg Businessweek," and "Washington Monthly" do not pay them much mind. What is the best…

  4. Multiple graph regularized protein domain ranking

    Directory of Open Access Journals (Sweden)

    Wang Jim

    2012-11-01

    Full Text Available Abstract Background Protein domain ranking is a fundamental task in structural biology. Most protein domain ranking methods rely on the pairwise comparison of protein domains while neglecting the global manifold structure of the protein domain database. Recently, graph regularized ranking that exploits the global structure of the graph defined by the pairwise similarities has been proposed. However, the existing graph regularized ranking methods are very sensitive to the choice of the graph model and parameters, and this remains a difficult problem for most of the protein domain ranking methods. Results To tackle this problem, we have developed the Multiple Graph regularized Ranking algorithm, MultiG-Rank. Instead of using a single graph to regularize the ranking scores, MultiG-Rank approximates the intrinsic manifold of protein domain distribution by combining multiple initial graphs for the regularization. Graph weights are learned with ranking scores jointly and automatically, by alternately minimizing an objective function in an iterative algorithm. Experimental results on a subset of the ASTRAL SCOP protein domain database demonstrate that MultiG-Rank achieves a better ranking performance than single graph regularized ranking methods and pairwise similarity based ranking methods. Conclusion The problem of graph model and parameter selection in graph regularized protein domain ranking can be solved effectively by combining multiple graphs. This aspect of generalization introduces a new frontier in applying multiple graphs to solving protein domain ranking applications.

  5. Multiple graph regularized protein domain ranking

    KAUST Repository

    Wang, Jim Jing-Yan

    2012-11-19

    Background: Protein domain ranking is a fundamental task in structural biology. Most protein domain ranking methods rely on the pairwise comparison of protein domains while neglecting the global manifold structure of the protein domain database. Recently, graph regularized ranking that exploits the global structure of the graph defined by the pairwise similarities has been proposed. However, the existing graph regularized ranking methods are very sensitive to the choice of the graph model and parameters, and this remains a difficult problem for most of the protein domain ranking methods.Results: To tackle this problem, we have developed the Multiple Graph regularized Ranking algorithm, MultiG-Rank. Instead of using a single graph to regularize the ranking scores, MultiG-Rank approximates the intrinsic manifold of protein domain distribution by combining multiple initial graphs for the regularization. Graph weights are learned with ranking scores jointly and automatically, by alternately minimizing an objective function in an iterative algorithm. Experimental results on a subset of the ASTRAL SCOP protein domain database demonstrate that MultiG-Rank achieves a better ranking performance than single graph regularized ranking methods and pairwise similarity based ranking methods.Conclusion: The problem of graph model and parameter selection in graph regularized protein domain ranking can be solved effectively by combining multiple graphs. This aspect of generalization introduces a new frontier in applying multiple graphs to solving protein domain ranking applications. 2012 Wang et al; licensee BioMed Central Ltd.

  6. The Globalization of College and University Rankings

    Science.gov (United States)

    Altbach, Philip G.

    2012-01-01

    In the era of globalization, accountability, and benchmarking, university rankings have achieved a kind of iconic status. The major ones--the Academic Ranking of World Universities (ARWU, or the "Shanghai rankings"), the QS (Quacquarelli Symonds Limited) World University Rankings, and the "Times Higher Education" World…

  7. Colworth prize lecture 2016: exploiting new biological targets from a whole-cell phenotypic screening campaign for TB drug discovery.

    Science.gov (United States)

    Moynihan, Patrick Joseph; Besra, Gurdyal S

    2017-10-01

    Mycobacterium tuberculosis is the aetiological agent of tuberculosis (TB) and is the leading bacterial cause of mortality and morbidity in the world. One third of the world's population is infected with TB, and in conjunction with HIV represents a serious problem that urgently needs addressing. TB is a disease of poverty and mostly affects young adults in their productive years, primarily in the developing world. The most recent report from the World Health Organisation states that 8 million new cases of TB were reported and that ~1.5 million people died from TB. The efficacy of treatment is threatened by the emergence of multi-drug and extensively drug-resistant strains of M. tuberculosis. It can be argued that, globally, M. tuberculosis is the single most important infectious agent affecting mankind. Our research aims to establish an academic-industrial partnership with the goal of discovering new drug targets and hit-to-lead new chemical entities for TB drug discovery.

  8. Elizabeth Warrington Prize Lecture. Seeing why they cannot see: understanding the syndrome and causes of posterior cortical atrophy.

    Science.gov (United States)

    Crutch, Sebastian J

    2014-09-01

    Posterior cortical atrophy (PCA) is a syndrome defined by focal neurodegeneration of the parietal, occipital, and occipito-temporal cortices and associated with progressive dysfunction of visual processing, praxis, numeracy and reading. The condition is most commonly caused by (and viewed as an atypical presentation of) Alzheimer's disease, although can also be caused by other degenerative diseases. The current paper examines the relationship of PCA to other degenerative syndromes, and considers what comparisons of these syndromes and disease phenotypes can tell us about underlying disease mechanisms. The focus then turns to neuropsychological investigations of the cognitive basis of symptoms which, although unusual in the broader context of a dementia clinic, are particularly characteristic of the PCA syndrome, before exploring implications for clinical management and patient and carer support. © 2013 The British Psychological Society.

  9. [Commemorative lecture of receiving Imamura Memorial Prize. Characterization of immunosuppressive macrophages induced in mice infected with Mycobacterium intracellulare].

    Science.gov (United States)

    Tomioka, H

    1993-12-01

    Functional changes in T lymphocytes and macrophages (M phi s) in host mice during the course of Mycobacterium intracellulare infection were studied. In both strains of mice, BALB/c or C57BL/6 (susceptible to M. avium complex) and CBA/JN or C3H/He (resistant to M. avium complex), the smooth, opaque and dome-shaped colonial (SmD) variants of M. intracellulare were easily eliminated from the sites after week 2 of infection. In contrast, the smooth, transparent and irregularly shaped colonial (SmT) variants showed steady growth in the former strains of mice and persisted for long time even in the latter strains of mice. No difference was found between persistence of the organisms in euthymic (+/+) and athymic (nu/nu) BALB/c mice during the first 4 weeks after infection. Thereafter, more rapid growth was seen in the spleens and lungs of nu/nu mice. Thus, matured T cells may be important for the prevention of the progression of M. intracellulare infection to the terminal state. Next, the profiles of generation and characteristics of splenic M phi s which suppress the Con A mitogenic response of splenic T cells in host CBA/JN or BALB/c mice during the course of M. intracellulare infection were investigated. In M. intracellulare--infected mice, reduction in some cellular functions of host splenic T cells, such as the Con A mitogenic response and mixed leucocyte reaction, were seen around 2 weeks after infection, and this was accompanied by appearance of immunosuppressive M phi s in spleen cells (SPCs).(ABSTRACT TRUNCATED AT 250 WORDS)

  10. The Wellcome Prize Lecture. A map of auditory space in the mammalian brain: neural computation and development.

    Science.gov (United States)

    King, A J

    1993-09-01

    The experiments described in this review have demonstrated that the SC contains a two-dimensional map of auditory space, which is synthesized within the brain using a combination of monaural and binaural localization cues. There is also an adaptive fusion of auditory and visual space in this midbrain nucleus, providing for a common access to the motor pathways that control orientation behaviour. This necessitates a highly plastic relationship between the visual and auditory systems, both during postnatal development and in adult life. Because of the independent mobility of difference sense organs, gating mechanisms are incorporated into the auditory representation to provide up-to-date information about the spatial orientation of the eyes and ears. The SC therefore provides a valuable model system for studying a number of important issues in brain function, including the neural coding of sound location, the co-ordination of spatial information between different sensory systems, and the integration of sensory signals with motor outputs.

  11. Evolution of Long-Term Adjuvant Anti-hormone Therapy: Consequences and Opportunities. The St. Gallen Prize Lecture

    Science.gov (United States)

    Jordan, V. Craig; Obiorah, Ifeyinwa; Fan, Ping; Kim, Helen R.; Ariazi, Eric; Cunliffe, Heather; Brauch, Hiltrud

    2012-01-01

    The successful translation of the scientific principles of targeting the breast tumour oestrogen receptor (ER) with the nonsteroidal anti-oestrogen tamoxifen and using extended durations (at least 5-years) of adjuvant therapy, dramatically increased patient survivorship and significantly enhanced a drop in national mortality rates from breast cancer. The principles are the same for the validation of aromatase inhibitors to treat post-menopausal patients but tamoxifen remains a cheap, life-saving medicine for the pre-menopausal patient. Results from the Oxford Overview Analysis illustrate the scientific principle of “longer is better” for adjuvant therapy in pre-menopausal patients. One-year of adjuvant therapy is ineffective at preventing disease recurrence or reducing mortality, whereas five-years of adjuvant tamoxifen reduces recurrence by 50% which is maintained for a further ten-years after treatment stops. Mortality is reduced but the magnitude continues to increase to 30% over a 15-year period. With this clinical database, it is now possible to implement simple solutions to enhance survivorship. Compliance with long-term anti-hormone adjuvant therapy is critical. In this regard, the use of selective serotonin reuptake inhibitors (SSRIs) to reduce severe menopausal side effects may be inappropriate. It is known that SSRIs block the CYP2D6 enzyme that metabolically activates tamoxifen to its potent anti-oestrogenic metabolite, endoxifen. The selective nor-epinephrine reuptake inhibitor, venlafaxine, does not block CYP2D6, and may be a better choice. Nevertheless, even with perfect compliance, the relentless drive of the breast cancer cell to acquire resistance to therapy persists. The clinical application of long-term anti-hormonal therapy for the early treatment and prevention of breast cancer, focused laboratory research on the discovery of mechanisms involved in acquired anti-hormone resistance. Decades of laboratory study to reproduce clinical experience described not only the unique mechanism of SERM-stimulated breast cancer growth, but also a new apoptotic biology of oestradiol action in breast cancer, following 5-years of anti-hormonal treatment. Oestradiol-induced apoptotic therapy is currently shown to be successful for the short-term treatment of metastatic ER positive breast cancer following exhaustive treatment with anti-hormones. The “oestrogen purge” concept is now being integrated into trials of long-term adjuvant anti-hormone therapy. The Study of Letrazole Extension (SOLE) trial employs “anti-hormonal drug holidays” so that a woman’s own oestrogen may periodically purge and kill the nascent sensitized breast cancer cells that are developing. This is the translation of an idea first proposed at the 1992 St. Gallen Conference. Although tamoxifen is the first successful targeted therapy in cancer, the pioneering medicine is more than that. A study of the pharmacology of tamoxifen opened the door for a pioneering application in cancer chemoprevention and created a new drug group: the Selective ER Modulators (SERMs) with group members (raloxifene and lasofoxifene) approved for the treatment and prevention of osteoporosis with a simultaneous reduction of breast cancer risk. Thus, the combined strategies of long-term anti-hormone adjuvant therapy, targeted to the breast tumour ER, coupled with the expanding use of SERMs to prevent osteoporosis and prevent breast cancer as a beneficial side effect have advanced patient survivorship significantly and promises to reduce breast cancer incidence. PMID:22015273

  12. Earle K. Plyler Prize for Molecular Spectroscopy and Dynamics Lecture: 2D IR Spectroscopy of Peptide Conformation

    Science.gov (United States)

    Tokmakoff, Andrei

    2012-02-01

    Descriptions of protein and peptide conformation are colored by the methods we use to study them. Protein x-ray and NMR structures often lead to impressions of rigid or well-defined conformations, even though these are dynamic molecules. The conformational fluctuations and disorder of proteins and peptides is more difficult to quantify. This presentation will describe an approach toward characterizing and quantifying structural heterogeneity and disorder in peptides using 2D IR spectroscopy. Using amide I vibrational spectroscopy, isotope labeling strategies, and computational modeling based on molecular dynamics simulations and Markov state models allows us to characterize distinct peptide conformers and conformational variation. The examples illustrated include the beta-hairpin tripzip2 and elastin-like peptides.

  13. Aneesur Rahman Prize for Computational Physics Lecture: Photonic Crystals and Genetic Algorithms: Adventures of a Computational Physicist

    Science.gov (United States)

    Ho, Kai Ming

    2012-02-01

    I will review some of our work in the computation of photonic crystals, focusing on our discovery of the photonic band gap in diamond structures. I will also describe our conception of the cut-and-paste genetic algorithm in materials discovery structure search and discuss applications of the algorithm from early studies of atomic clusters geometries to more recent applications for structures of surfaces, interfaces, nanowires, and bulk crystals.

  14. Irving Langmuir Prize in Chemical Physics Lecture: The Inner Machinery of Single Molecules: resolving the unresolved with the STM

    Science.gov (United States)

    Ho, Wilson

    2013-03-01

    The scanning tunneling microscope (STM) is a unique instrument that can probe and induce changes in a molecule with atomic scale resolution. Its operation is based on the current that flows between the tip and the substrate with the molecule sandwiched in between. Therefore, the STM can be used to understand the coupling of electrons to the different states and excitations in the molecule and to investigate the influence on them by its environment. From the spatial and energy dependences of the coupling to the charge, spin, and nuclear motions in the molecule, verification of and new insights into the quantum mechanical properties of molecules can be obtained, including the discovery of new conduction and energy transfer mechanisms. This understanding of electron-molecule interactions with the STM enables rational ways to control chemistry and the exploration of novel physical technologies based on molecules.

  15. Prize for a Faculty Member for Research in an Undergraduate Institution Lecture: Research (Teaching) with Bose-Einstein Condensates

    Science.gov (United States)

    Hall, David

    2012-06-01

    Bose-Einstein condensation in dilute gases, with its myriad ramifications in fields as diverse as atomic, condensed-matter, cosmological, fluid, quantum, and statistical physics, offers unique possibilities for the synthesis of research and pedagogy. The highly visual nature of the experiments can make Bose-Einstein condensates a particularly compelling teaching instrument, particularly for those encountering these topics for the first time. The associated technological challenges provide copious opportunities for development of fundamental research skills while retaining the intimate context of tabletop research. Our program at Amherst College pursues studies of multicomponent condensates, tunable ultracold collisions (i.e., Feshbach resonances), and topological defects (e.g., vortices). In this talk I will describe our experimental efforts in these three principal directions, taken singly and in combination, with a nod to the peculiarities and opportunities inherent to an essentially undergraduate research program.

  16. New Frontiers/Hale Prize Lecture: Coronal Mass Ejections, the Most Powerful Drivers of the Sun-Earth System

    Science.gov (United States)

    Antiochos, S. K.

    2005-05-01

    A large Coronal Mass Ejection (CME) can consist of billions of tonnes of matter, along with entangled magnetic field, erupting from the Sun at speeds well over 1,000 km/s. These giant disruptions of the solar atmosphere drive the most destructive space weather at Earth and throughout the solar system. Furthermore, CMEs are the most dramatic example of how slowly-evolving processes on the Sun can conspire to produce explosive activity. Understanding their origin has long been a central objective for space physics research. This talk will present some of the latest observations and theories for CMEs and discuss the outstanding challenges to modeling and predicting their initiation. This work was supported in part by NASA and ONR.

  17. Andreas Acrivos Dissertation Prize Lecture: Quantum Mechanics meets Fluid Dynamics: Visualization of Vortex Reconnection in Superfluid Helium

    Science.gov (United States)

    Paoletti, Matthew

    2010-11-01

    Long-range quantum order underlies a number of related physical phenomena including superfluidity, superconductivity and Bose-Einstein condensation. While superfluidity in helium-4 was one of the earliest discovered, it is not the best understood, owing to the strong interactions present (making theoretical progress difficult) and the lack of local experimental probes. Quantum fluids, such as superfluid helium-4, are typically described as a mixture of two interpenetrating fluids with distinct velocity fields: a viscous normal fluid akin to water and an inviscid superfluid exhibiting long-range quantum order. In this "two-fluid model," there is no conventional viscous dissipation in the superfluid component and vorticity is confined to atomically-thin vortices with quantized circulation. Turbulence may occur in either fluid component with turbulence in the superfluid exhibiting a complex tangle of quantized vortices, as first envisioned by Feynman. Approximately five years ago, our group discovered that micron-sized hydrogen particles may be used for flow visualization in superfluid helium-4. The particles can trace the motions of the normal fluid or be trapped by the quantized vortices, which enables one to characterize the dynamics of both the normal fluid and superfluid components for the first time. By directly observing and tracking these particles, we have directly confirmed the two-fluid model, observed vortex rings and quantized vortex reconnection, characterized thermal counterflows, and observed the very peculiar nature of quantum turbulence. One of many surprising observations is the existence of power-law tails in the probability distribution of velocities in quantum turbulence, which are in stark contrast to the Gaussian distributions typical of classical fluid turbulence.

  18. Earle K. Plyler Prize for Molecular Spectroscopy & Dynamics Lecture: Broadband Rotational Spectroscopy for Chemical Kinetics, Molecular Structure, and Analytical Chemistry

    Science.gov (United States)

    Pate, Brooks

    2013-03-01

    Advances in high-speed digital electronics have enabled a new generation of molecular rotational spectroscopy techniques that provide instantaneous broadband spectral coverage. These techniques use a chirped excitation pulse to coherently excite the molecular sample over a spectral bandwidth of 10 GHz or larger through rapid passage. The subsequent time-domain emission is recorded using high-speed digitizers (up to 100 Gigasample/s) and the frequency domain spectrum is produced by fast Fourier transformation. The chirped-pulse Fourier transform (CP-FT) method has been implemented in the microwave frequency range (2-40 GHz) for studies of cold samples in pulsed jet sources and in the mm-wave/terahertz (THz) frequency range for studies of samples at room-temperature. The method has opened new applications for molecular rotational spectroscopy in the area of chemical kinetics where dynamic rotational spectroscopy is used to measure the rates of unimolecular isomerization reactions in highly excited molecules prepared by pulsed infrared laser excitation. In these applications, the isomerization rate is obtained from an analysis of the overall line shapes which are modified by chemical exchange leading to coalescence behavior similar to the effect in NMR spectroscopy. The sensitivity of the method and the ability to extend it to low frequency (2-8 GHz) have significantly increased the size range of molecules and molecular clusters for structure determination using isotopic substitution to build up the 3D molecular structures atom-by-atom. Application to the structure of water clusters with up to 15 water molecules will be presented. When coupled with advances in solid-state mm-wave/THz devices, this method provides a direct digital technique for analytical chemistry of room-temperature gases based on molecular rotational spectroscopy. These high-throughput methods can analyze complex sample mixtures with unmatched chemical selectivity and short analysis times. Work Supported by the NSF MRI Program.

  19. Will Allis Prize for the Study of Ionized Gases Lecture: Electron and Photon Collisions with Atoms and Molecules

    Science.gov (United States)

    Burke, Philip G.

    2012-06-01

    After a brief historical introduction this talk will review the broad range of collision processes involving electron and photon collisions with atoms and molecules that are now being considered. Their application in the analysis of astronomical spectra, atmospheric observations and laboratory plasmas will be considered. The talk will review the R-matrix computational method which has been widely used by international collaborations and by other scientists in the field to obtain accurate scattering amplitudes and cross sections of importance in these applications. Results of some recent calculations of electron and photon collisions with atoms and molecules will be presented. In conclusion some challenges for future research will be briefly discussed.

  20. Oliver E. Buckley Condensed Matter Prize Lecture: S-d Exchange, Spin Accumulation, And The Roots Of Spintronics

    Science.gov (United States)

    Berger, Luc

    2013-03-01

    The success of spintronics in metals such as nickel, cobalt, Ni-Fe and Ni-Co is based on the existence of high-mobility spin-up 4s electrons at the Fermi level, which carry most of the current. The spin-up Fermi level is located above the top of the 3d band. This basic fact, first recognized by Mott in 1936, was confirmed by the Hall-effect measurements of Pugh et al. (1950-1965), and by data of deviation from Matthiessen's rule by Campbell, Fert and Jaoul (1967-1977). In order to explain giant magnetoresistance and the existence of the spin-transfer torque, an interaction is needed which couples 4s conduction electrons to magnetic 3d electrons. This is the s-d exchange interaction, introduced by Vonsovskii in 1946 and Zener in 1951. Theories of Gilbert damping, based on s-d exchange, were soon developed (Turov (1955), Mitchell (1957)). But a serious problem was caused by the existence of a momentum gap between spin-up and spin-down Fermi surfaces, which prevents spin switching from happening at low T. The problem can be solved if local defects exist which act as extra sources of momentum. One such source is spin-flip scattering (Turov (1961), Heinrich, Freitova and Kambersky (1967)). A second one is the presence of an interface (Slonczewski (1996), Berger (1996)). Spin accumulation is another concept of importance to spintronics. It represents an imbalance between spin-up and spin-down Fermi levels. Introduced by Aronov in 1976, it was developed by Johnson and Silsbee (1985-1993) and by Valet and Fert (1993). It is the hidden agent through which the current ``pumps'' energy into many spintronics devices. In semiconductor lasers, the same role is played by the difference between conduction-band and valence-band Fermi levels. A momentum gap problem also exists in lasers made of indirect-gap semiconductors, and it is solved similarly.

  1. Lilienfeld Prize Lecture: Life, The Universe, and Nothing: Life and Death in an Ever-Expanding Universe

    Science.gov (United States)

    Krauss, Lawrence M.

    2001-04-01

    In this talk, I will ruminate on the future of the Universe, and also on the future of life within it, using as my starting point recent observations in cosmology that have changed the way we think about the Universe on large scales. I will briefly review these observations and then discuss why the Universe we appear to inhabit may be the worst of all possible universes, as far as the long-term quality and quantity of life is concerned. Then, I will describe how fundamental aspects of the way in which we teach cosmology, in particular the relation between geometry and destiny, have been altered by the recognition that the cosmological constant may be zero. Finally, I will introduce the fascinating, if somewhat academic question of whether life can be eternal in an eternally expanding universe. Surprisingly, perhaps, the answer to this question appears to hinge on issues of basic physics, in particular on issues of quantum mechanics and computation, which may determine whether life is ultimately analogue or digital.

  2. [Commemorative lecture of receiving Imamura Memorial Prize. NK cell in pulmonary tuberculosis from basic and clinical point of view].

    Science.gov (United States)

    Yoneda, T

    1996-11-01

    Although natural killer (NK) cells, which lyse certain tumors in vitro, have been shown to provide early defense mechanism against cancer growth and viral infection, possible role in the host defense against pulmonary tuberculosis remains undefined. A series of my studies have recently provided several evidence supporting the involvement of NK cells in the immunopathology of pulmonary tuberculosis. NK cell activity in patients with active pulmonary tuberculosis was significantly augmented compared with that in age-, sex- matched healthy controls, which suggests NK cells are activated in vivo in pulmonary tuberculosis. Lung NK cells from BCG-infected mice also are shown to be activated. Asialo GM 1 was demonstrated to be a novel surface marker of mice NK cells, which inhibited activation of NK cells by interferon. Chronic intractable tuberculosis was classified with a combination of NK cell activity and delayed-type hypersensitivity reaction to 2, 4-dinitrochrolbenzene. Subgroup defined with high NK cell activity and normal delayed-type hypersensitivity was characterized with moderate radiographical lesions and stable clinical course, suggesting the immune-spectrum classification was associated with clinical manifestations. Malnutrition has been suggested to be a risk factor associated with the development and reactivation of pulmonary tuberculosis. NK cell activity was significantly correlated with visceral proteins. IL-2 producing capability was significantly decreased in patients with serum albumin less than 3.5 g/dl. More recently, I established an in vitro system evaluating quantitative capability for intracellular killing by human monocytes, in which monocyte phagocytize Mycobacterium tuberculosis and subsequently inhibit intracellular replication of the organisms by adding some cytokines or cells. Purified NK cells by using discontinuous gradient centrifugation and magnetic separation technique were added to M. tuberculosis-infected monocytes monolayer. Purified NK cells inhibit intracellular replication within monocytes in dose response manner.

  3. [Commemorative lecture of receiving Imamura Memorial Prize. II. Mode of action of oligonucleotide fraction extracted from Mycobacterium bovis BCG].

    Science.gov (United States)

    Yamamoto, S

    1994-09-01

    A fraction extracted from Mycobacterium bovis BCG was found to exhibit strong antitumor activity. This fraction, which was designated MY-1, caused some animal tumors to regress and/or prevent metastasis very effectively. MY-1 after digestion with DNase had almost completely reduced activity, while MY-1 digested with RNase did not. MY-1 also augmented natural killer (NK) cell activity of mouse spleen cells in vitro, and produced factors which showed anti-viral activity and rendered macrophages cytotoxic towards tumor cells. The function of the factor to activate macrophages was destroyed by treatment with anti-interferon (IFN)-gamma antibody, while the anti-viral activity was destroyed by treatment with anti-INF alpha/beta antibody. The oligonucleotides contained in MY-1 distributed in a broad range of molecular size, and peaked at 45 nucleotides. We synthesized 13 kinds of 45-mer nucleotides with sequence present in the known cDNA encoding various BCG proteins. Six out of these oligonucleotides, which contained one or more hexameric palindromic structures, showed strong antitumor activity, while the other without palindrome did not. These active oligonucleotides possessed the capability to induce IFN and to augment NK cell activity of mouse spleen cells by coincubation in vitro. When a portion of the sequence of the inactive oligonucleotides was substituted with either palindromic sequence of GACGTC, AGCGCT or AACGTT, the oligonucleotide acquired the ability to augment NK activity. In contrast, the oligonucleotides substituted with another palindromic sequence such as ACCGGT was without effect. Furthermore, exchange of two neighboring mononucleotides within, but not outside, the active palindromic sequence destroyed the ability of the oligonucleotide to augment NK activity.(ABSTRACT TRUNCATED AT 250 WORDS)

  4. [Commemorative lecture of receiving Imamura Memorial Prize. III. Estimating the year of eradication of tuberculosis in Japan].

    Science.gov (United States)

    Ohmori, M

    1994-09-01

    The year by which tuberculosis could be eradicated, has been discussed for several foreign countries, and based on those results, new strategic plans and goals have been elaborated. Therefore, in Japan too, it was desired to estimate the point at which eradication of tuberculosis would be achieved. The author estimated the year of eradication of tuberculosis, according to the criterion proposed by Dr. Styblo that "tuberculosis is eradicated when the prevalence of tuberculosis infection in the general population has fallen below 1% and continues to decrease". If the risk of infection is changing at a regular rate, it is possible to estimate the risk of infection at any particular time. Once the risk of infection is determined, it is also possible to calculate the age-specific prevalence of infection and the proportion of the population infected with tubercle bacilli at any given time. In Japan, the risk of infection before World War II was assumed to be around 4%; since then, it has declined on average, by 10 to 11% annually. The incidence rate in Japan also has declined, on average, by 10 to 11% annually. However, since late 1970s, the annual speed of decline of the incidence rate has slowed down. Therefore, I assumed that the recent trend of the infection risk is the same as the trend of the recent incidence rate among the 0-29 year age-group. The size of the effect of age on the risk of infection has been discussed. The author also considered age-effects in the model.(ABSTRACT TRUNCATED AT 250 WORDS)

  5. Robert R. Wilson Prize for Achievement in the Physics of Particle Accelerators Lecture: Frontiers of FEL Physics and Technology

    Science.gov (United States)

    Madey, John M. J.

    2012-03-01

    For much of the past 40 years, efforts to advance the capabilities of FELs have focussed on the frontiers of operation at high average power and short wavelengths with impressive and gratifying results. But a number of potentially important additional frontiers remain to be explored. I will briefly describe several of the new areas in which we have worked relating to the exploitation of boundary conditions to enhance oscillator phase coherence and stability, the exploitation of phase coherence to reduce the quantum fluctuations in amplitude of the coherent harmonics, the elucidation of the classical Wheeler-Feynman coherent radiation reaction force in single pass radiation sources, the development of the precision, robust high peak and average power optical elements needed for the reliable operation of these sources and the application of these advances to the development of optimized inverse-Compton x-ray and gamma ray sources.

  6. Robert Feulgen Prize Lecture 1993. The journey of the insulin receptor into the cell: from cellular biology to pathophysiology.

    Science.gov (United States)

    Carpentier, J L

    1993-09-01

    The data that we have reviewed indicate that insulin binds to a specific cell-surface receptor. The complex then becomes involved in a series of steps which lead the insulin-receptor complex to be internalized and rapidly delivered to endosomes. From this sorting station, the hormone is targeted to lysosomes to be degraded while the receptor is recycled back to the cell surface. This sequence of events presents two degrees of ligand specificity: (a) The first step is ligand-dependent and requires insulin-induced receptor phosphorylation of specific tyrosine residues. It consists in the surface redistribution of the receptor from microvilli where it preferentially localizes in its unoccupied form. (b) The second step is more general and consists in the association with clathrin-coated pits which represents the internalization gate common to many receptors. This sequence of events participates in the regulation of the biological action of the hormone and can thus be implicated in the pathophysiology of diabetes mellitus and various extreme insulin resistance syndromes, including type A extreme insulin resistance, leprechaunism, and Rabson-Mendehall syndrome. Alterations of the internalization process can result either from intrinsic abnormalities of the receptor or from more general alteration of the plasma membrane or of the cell metabolism. Type I diabetes is an example of the latter possibility, since general impairment of endocytosis could contribute to extracellular matrix accumulation and to an increase in blood cholesterol. Thus, better characterization of the molecular and cellular biology of the insulin receptor and of its journey inside the cell definitely leads to better understanding of disease states, including diabetes.

  7. The St. Gallen Prize Lecture 2011: evolution of long-term adjuvant anti-hormone therapy: consequences and opportunities.

    Science.gov (United States)

    Jordan, V Craig; Obiorah, Ifeyinwa; Fan, Ping; Kim, Helen R; Ariazi, Eric; Cunliffe, Heather; Brauch, Hiltrud

    2011-10-01

    The successful translation of the scientific principles of targeting the breast tumour oestrogen receptor (ER) with the nonsteroidal anti-oestrogen tamoxifen and using extended durations (at least 5 years) of adjuvant therapy, dramatically increased patient survivorship and significantly enhanced a drop in national mortality rates from breast cancer. The principles are the same for the validation of aromatase inhibitors to treat post-menopausal patients but tamoxifen remains a cheap, life-saving medicine for the pre-menopausal patient. Results from the Oxford Overview Analysis illustrate the scientific principle of "longer is better" for adjuvant therapy in pre-menopausal patients. One year of adjuvant therapy is ineffective at preventing disease recurrence or reducing mortality, whereas five years of adjuvant tamoxifen reduces recurrence by 50% which is maintained for a further ten years after treatment stops. Mortality is reduced but the magnitude continues to increase to 30% over a 15-year period. With this clinical database, it is now possible to implement simple solutions to enhance survivorship. Compliance with long-term anti-hormone adjuvant therapy is critical. In this regard, the use of selective serotonin reuptake inhibitors (SSRIs) to reduce severe menopausal side effects may be inappropriate. It is known that SSRIs block the CYP2D6 enzyme that metabolically activates tamoxifen to its potent anti-oestrogenic metabolite, endoxifen. The selective norepinephrine reuptake inhibitor, venlafaxine, does not block CYP2D6, and may be a better choice. Nevertheless, even with perfect compliance, the relentless drive of the breast cancer cell to acquire resistance to therapy persists. The clinical application of long-term anti-hormonal therapy for the early treatment and prevention of breast cancer, focused laboratory research on the discovery of mechanisms involved in acquired anti-hormone resistance. Decades of laboratory study to reproduce clinical experience described not only the unique mechanism of selective ER modulator (SERM)-stimulated breast cancer growth, but also a new apoptotic biology of oestradiol action in breast cancer, following 5 years of anti-hormonal treatment. Oestradiol-induced apoptotic therapy is currently shown to be successful for the short-term treatment of metastatic ER positive breast cancer following exhaustive treatment with anti-hormones. The "oestrogen purge" concept is now being integrated into trials of long-term adjuvant anti-hormone therapy. The Study of Letrazole Extension (SOLE) trial employs "anti-hormonal drug holidays" so that a woman's own oestrogen may periodically purge and kill the nascent sensitized breast cancer cells that are developing. This is the translation of an idea first proposed at the 1992 St. Gallen Conference. Although tamoxifen is the first successful targeted therapy in cancer, the pioneering medicine is more than that. A study of the pharmacology of tamoxifen opened the door for a pioneering application in cancer chemoprevention and created a new drug group: the SERMs, with group members (raloxifene and lasofoxifene) approved for the treatment and prevention of osteoporosis with a simultaneous reduction of breast cancer risk. Thus, the combined strategies of long-term anti-hormone adjuvant therapy, targeted to the breast tumour ER, coupled with the expanding use of SERMs to prevent osteoporosis and prevent breast cancer as a beneficial side effect, have advanced patient survivorship significantly and promise to reduce breast cancer incidence. Copyright © 2011 Elsevier Ltd. All rights reserved.

  8. J. J. Sakurai Prize for Theoretical Particle Physics Lecture: Some QCD aspects of physics beyond the standard model

    Science.gov (United States)

    Sjostrand, Torbjorn

    2012-03-01

    The nature of observable events at the LHC is mainly determined by QCD physics, i.e. strong interactions. The search for new physics obviously implies a desire to go beyond QCD. Nevertheless, also in cases where non-QCD processes are studied, new aspects of QCD physics may enter the back door. We here give three examples: decays with R-parity violation in SUSY, the formation of long-lived R-hadrons in SUSY, and parton showers and hadronization in Hidden Valley scenarios. These three possibilities have been implemented in the general-purpose PYTHIA event generator, so that detailed studies of consequences can be performed.

  9. 1991 Urey Prize Lecture: Physical evolution in the solar system - Present observations as a key to the past

    Science.gov (United States)

    Binzel, Richard P.

    1992-01-01

    The present evaluation of the use of new observational methods for exploring solar system evolutionary processes gives attention to illustrative cases from the constraining of near-earth asteroid sources and the discovery of main-belt asteroid fragments which indicate Vesta to be a source of basaltic achondrite meteorites. The coupling of observational constraints with numerical models clarifies cratering and collisional evolution for both main-belt and Trojan asteroids.

  10. Oliver E. Buckley Condensed Matter Prize Lecture: Transfer of spin momentum between magnets: its genesis and prospect

    Science.gov (United States)

    Slonczewski, John

    2013-03-01

    Consider two nanoscopic monodomain magnets connected by a spacer that is composed of a non-magnetic metal or a tunnel barrier. Any externally applied electric current flowing through these three layers contributes tiny pseudo-torques to both magnetic moments (J . S . 1989). Such a weak spin-transfer torque (STT) may counteract and overcome a comparably small torque caused by viscous dissipation (L. Berger1996; J . S . 1996). Any initial motion (e. g. excited by ambient temperature) of one moment (or both), may grow in amplitude and culminate in steady precession or a transient switch to a new direction of static equilibrium. In a memory element, the STT effect writes 0 or 1 in a magnetic-tunnel junction. Indeed, world-wide developments of memory arrays and radio-frequency oscillators utilizing current-driven STT today enjoy a nine-digit dollar commitment. But the fact that transfer of each half-unit of spin momentum h/4 π through a barrier requires the transfer of at least one unit of electric charge limits its efficiency. Arguably, STT should also arise from the flow of external heat, in either direction, between an insulating magnet, of ferrite or garnet (e. g. YIG) composition, and a metallic spacer (J . S . 2010). Whenever s-d exchange annihilates a hot magnon at the insulator/metal-spacer interface, it transfers one unit h/2 π of spin momentum to the spacer. Conduction electrons within the spacer will transport this spin momentum to the second magnet without requiring an electric current. Such a thermagnonicmethod, modestly powered by a Joule-effect heater, can substantially increase the efficiency of STT. Support for this prediction comes from (1) an estimate of the sd-exchange coefficient from data on spin relaxation in magnetically dilute (Cu,Ag,Au):Mn alloys; (2) a DFT computation (J. Xiao et al 2010); and (3) most persuasively, data from spin pumping driven across a YIG/Au interface by ferromagnetic resonance (B. Heinrich et al 2011; C. Burrowes et al 2012).

  11. Robert Feulgen Prize Lecture. Distribution and role of gap junctions in normal myocardium and human ischaemic heart disease.

    Science.gov (United States)

    Green, C R; Severs, N J

    1993-02-01

    In the heart, individual cardiac muscle cells are linked by gap junctions. These junctions form low resistance pathways along which the electrical impulse flows rapidly and repeatedly between all the cells of the myocardium, ensuring their synchronous contraction. To obtain probes for mapping the distribution of gap junctions in cardiac tissue, polyclonal antisera were raised to three synthetic peptides, each matching different cytoplasmically exposed portions of the sequence of connexin43, the major gap-junctional protein reported in the heart. The specificity of each antiserum for the peptide to which it was raised was established by dot blotting. New methods were developed for isolating enriched fractions of gap junctions from whole heart and from dissociated adult myocytes, in which detergent-treatment and raising the temperature (potentially damaging steps in previously described techniques) are avoided. Analysis of these fractions by SDS-polyacrylamide gel electrophoresis revealed major bands at 43 kDa (matching the molecular mass of connexin43) and at 70 kDa. Western blot experiments using our antisera indicated that both the 43-kDa and the 70-kDa bands represent cardiac gap-junctional proteins. Pre-embedding immunogold labelling of isolated gap junctions and post-embedding immunogold labelling of Lowicryl-embedded whole tissue demonstrated the specific binding of the antibodies to ultrastructurally defined gap junctions. One antiserum (raised to residues 131-142) was found to be particularly effective for cytochemical labelling. Using this antiserum for immunofluorescence labelling in combination with confocal scanning laser microscopy enabled highly sensitive detection and three-dimensional mapping of gap junctions through thick slices of cardiac tissue. By means of the serial optical sectioning ability of the confocal microscope, images of the entire gap junction population of complete en face-viewed disks were reconstructed. These reconstructions reveal the presence of large junctions arranged as a peripheral ring around the disk, with smaller junctions in an interior zone: an arrangement that may facilitate efficient intercellular transfer of current. By applying our immunolabelling techniques to tissue from hearts removed from transplant patients with advanced ischaemic heart disease, we have demonstrated that gap junction distribution between myocytes at the border zone of healed infarcts is markedly disordered. This abnormality may contribute to the genesis of reentrant arrhythmias in ischaemic heart disease.

  12. James C. McGroddy Prize for New Materials Lecture: New Superconductors and other Research in New Materials

    Science.gov (United States)

    Cava, Robert

    2012-02-01

    Superconductors and other electronic materials can often display subtle relationships between their structural characteristics and their electronic properties. Though the primary interest in these relationships is within the condensed matter physics community, often at their foundation are the concepts of bonding and structure familiar to inorganic and solid state chemists. Thus a hybridized view, combining physics and chemistry, is one way of approaching the discovery and characterization of new materials. In this talk I will describe some of our research in this context and comment on some broader aspects of interdisciplinary research in new materials.

  13. Davisson-Germer Prize in Atomic or Surface Physics Lecture: Line 'Em All Up: Macromolecular Assembly at Liquid Interfaces

    Science.gov (United States)

    Richmond, Geraldine

    2013-03-01

    Advances in our molecular level understanding of the ubiquitous fluid interface comprised of a hydrophobic fluid medium, and an aqueous solution of soluble ions and solutes has been slow until recently. This more recent upsurge in interest and progress comes from advances in both experimental and computational techniques as well as the increasingly important role that this interface is playing in such areas as green chemistry, nanoparticle synthesis, improved oil and mineral recovery and water purification. The presentation will focus on our most recent efforts in understanding (1) the molecular structure of the interface between two immiscible liquids, (2) the penetration of aqueous phase ions into the interfacial region and their effect on its properties, and (3) the structure and dynamics of the adsorption of surfactants, polymers and nanoparticles at this interface. To gain insights into these processes we use a combination of vibrational sum frequency spectroscopy, surface tension measurements using the pendant drop method, and molecular dynamics simulations. The results demonstrate that weak interactions between interfacial oil and water molecules create an interface that exhibits a high degree of molecular structuring and ordering, and with properties quite different than what is observed at the air-water interface. As a consequence of these interfacial oil-water interactions, the interface provides a unique environment for the adsorption and assembly of ions, polymers and nanoparticles that are drawn to its inner-most regions. Examples of our studies that provide new insights into the unique nature of adsorption, adsorption dynamics and macromolecular assembly at this interface will be provided.

  14. Abraham Pais Prize for History of Physics Lecture: Big, Bigger, Too Big? From Los Alamos to Fermilab and the SSC

    Science.gov (United States)

    Hoddeson, Lillian

    2012-03-01

    The modern era of big science emerged during World War II. Oppenheimer's Los Alamos laboratory offered the quintessential model of a government-funded, mission-oriented facility directed by a strong charismatic leader. The postwar beneficiaries of this model included the increasingly ambitious large laboratories that participated in particle physics--in particular, Brookhaven, SLAC, and Fermilab. They carried the big science they practiced into a new realm where experiments eventually became as large and costly as entire laboratories had been. Meanwhile the available funding grew more limited causing the physics research to be concentrated into fewer and bigger experiments that appeared never to end. The next phase in American high-energy physics was the Superconducting Super Collider, the most costly pure physics project ever attempted. The SSC's termination was a tragedy for American science, but for historians it offers an opportunity to understand what made the success of earlier large high-energy physics laboratories possible, and what made the continuation of the SSC impossible. The most obvious reason for the SSC's failure was its enormous and escalating budget, which Congress would no longer support. Other factors need to be recognized however: no leader could be found with directing skills as strong as those of Wilson, Panofsky, Lederman, or Richter; the scale of the project subjected it to uncomfortable public and Congressional scrutiny; and the DOE's enforcement of management procedures of the military-industrial complex that clashed with those typical of the scientific community led to the alienation and withdrawal of many of the most creative scientists, and to the perception and the reality of poor management. These factors, exacerbated by negative pressure from scientists in other fields and a post-Cold War climate in which physicists had little of their earlier cultural prestige, discouraged efforts to gain international support. They made the SSC crucially different from its predecessors and sealed its doom.

  15. Time evolution of Wikipedia network ranking

    Science.gov (United States)

    Eom, Young-Ho; Frahm, Klaus M.; Benczúr, András; Shepelyansky, Dima L.

    2013-12-01

    We study the time evolution of ranking and spectral properties of the Google matrix of English Wikipedia hyperlink network during years 2003-2011. The statistical properties of ranking of Wikipedia articles via PageRank and CheiRank probabilities, as well as the matrix spectrum, are shown to be stabilized for 2007-2011. A special emphasis is done on ranking of Wikipedia personalities and universities. We show that PageRank selection is dominated by politicians while 2DRank, which combines PageRank and CheiRank, gives more accent on personalities of arts. The Wikipedia PageRank of universities recovers 80% of top universities of Shanghai ranking during the considered time period.

  16. Lectures

    OpenAIRE

    Ceccaldi, Sylviane; Leménager, Nathalie; Thévenot, Magali

    2010-01-01

    Accès à l’emploi et insertion L'insertion professionnelle des travailleurs handicapés. En France, de 1987 à nos jours Blanc Alain (Dir.)Grenoble, PUG, 2009, 311 p.Collection « Handicap, Vieillissement, Société » Élaboré dans l'entre-deux-guerres, le dispositif d'insertion professionnelle dédié aux travailleurs handicapés a peu évolué : il se caractérise toujours par le triple processus de définition des bénéficiaires, de mise en œuvre d'actions de médiations leur permettant d'accéder à l'empl...

  17. Remark on receiving encouraging prize; Shoreisho jusho shokan

    Energy Technology Data Exchange (ETDEWEB)

    Mizutani, Tomichika [Meji University, Tokyo (Japan)

    1999-07-31

    The 1998 fiscal year Japan Solar Energy Soc. encouraging prize is received this time, and it is really sure of thank you and this winning prize for future research activity with large encouragement, while research activity in the university becomes in the good commemoration. This study also put environmental problem in visual field oil crisis energy resource worldwide new, and it was noticed in the wave energy which was one of the natural energy, it was started. That the wave energy was noticed, when the research of various natural energy was advanced, Over 10 years, it is the idea which was produced by the process in which the mechanics laboratory studies the vibration problem, and it is regarded as connecting with present winning prize as a summing-up of research result kept since the front. In the keyword of 'new{exclamation_point}' it began to leave Mr.Taichi Matsuoka and cooperation of the science graduate student as a partner of the graduation thesis the research the present it was a start from the nothing as a thing of this type. It is negative to advance this study in which the failure was always given here, when the new work began, of Mr.Matsuoka of the passion for the research. Away from the research of the wave power generation, solar light and wind power generation are noticed a little, and I aim at the hybridization of the wave power generation, and the research is advanced. Therefore, the vibration-proof stage for installing sun and wind energy conversion system on the wave-power device at present has been designed. At the end, the gratitude is shown to the everybody who received the enthusiastic guidance for this study. (translated by NEDO)

  18. Lecture Notes on Multigrid Methods

    Energy Technology Data Exchange (ETDEWEB)

    Vassilevski, P S

    2010-06-28

    The Lecture Notes are primarily based on a sequence of lectures given by the author while been a Fulbright scholar at 'St. Kliment Ohridski' University of Sofia, Sofia, Bulgaria during the winter semester of 2009-2010 academic year. The notes are somewhat expanded version of the actual one semester class he taught there. The material covered is slightly modified and adapted version of similar topics covered in the author's monograph 'Multilevel Block-Factorization Preconditioners' published in 2008 by Springer. The author tried to keep the notes as self-contained as possible. That is why the lecture notes begin with some basic introductory matrix-vector linear algebra, numerical PDEs (finite element) facts emphasizing the relations between functions in finite dimensional spaces and their coefficient vectors and respective norms. Then, some additional facts on the implementation of finite elements based on relation tables using the popular compressed sparse row (CSR) format are given. Also, typical condition number estimates of stiffness and mass matrices, the global matrix assembly from local element matrices are given as well. Finally, some basic introductory facts about stationary iterative methods, such as Gauss-Seidel and its symmetrized version are presented. The introductory material ends up with the smoothing property of the classical iterative methods and the main definition of two-grid iterative methods. From here on, the second part of the notes begins which deals with the various aspects of the principal TG and the numerous versions of the MG cycles. At the end, in part III, we briefly introduce algebraic versions of MG referred to as AMG, focusing on classes of AMG specialized for finite element matrices.

  19. Google Science Fair 2012 : Grand Prize Winner Brittany Wenger

    CERN Multimedia

    Maximilien Brice

    2012-01-01

    17-18 age category AND Grand Prize Winner: Brittany Wenger (USA)—“Global Neural Network Cloud Service for Breast Cancer.” Brittany’s project harnesses the power of the cloud to help doctors accurately diagnose breast cancer. Brittany built an application that compares individual test results to an extensive dataset stored in the cloud, allowing doctors to assess tumors using a minimally-invasive procedure. Brittany Michelle Wenger, and her mother, passed through the CERN Control Centre accompanied by Mike Lamont, CERN Beams Department, Operation Group Leader.

  20. Chronobiology --2017 Nobel Prize in Physiology or Medicine.

    Science.gov (United States)

    Yuan, Li; Li, Yi-Rou; Xu, Xiao-Dong

    2018-01-20

    Chronobiology is a field of biology that examines the generation of biological rhythms in various creatures and in many parts of body, and their adaptive fitness to solar- and lunar-related periodic phenomena. The synchronization of internal circadian clocks with external timing signals confers accurate phase response and tissue homeostasis. Herein we state a series of studies on circadian rhythms and introduce the brief history of chronobiology. We also present a detailed timeline of the discoveries on molecular mechanisms controlling circadian rhythm in Drosophila, which was awarded the 2017 Nobel Prize in Physiology or Medicine. The latest findings and new perspectives are further summarized to indicate the significance of circadian research.