WorldWideScience

Sample records for range user friendly

  1. User Friendly Explosives Reactive Armour a Long term Reality

    Directory of Open Access Journals (Sweden)

    S. N. Dikshit

    1997-04-01

    Full Text Available Abstract : There is a strong need to develop explosive reactive armour (ERA for protecting battle tanks against an emerging threat of kinetic and chemical energy missiles. In this context, global trends, principle and limitations of ERA and threat perception-based types of ERA have been dwelt upon. User-friendly ERA is a long-term reality. User-friendly ERA system is thus defined to be an efficient and protective system that not only provide full protection to the tank crew, but is also harmless to the supporting infantory. The indigenously-developed ERA system is close to be termed as a user-friendly ERA.

  2. User-friendly imaging algorithms for interferometry

    Science.gov (United States)

    Young, John; Thiébaut, Éric; Duvert, Gilles; Vannier, Martin; Garcia, Paulo; Mella, Guillaume

    2016-08-01

    OPTICON currently supports a Joint Research Activity (JRA) dedicated to providing easy to use image reconstruction algorithms for optical/IR interferometric data. This JRA aims to provide state-of-the-art image reconstruction methods with a common interface and comprehensive documentation to the community. These tools will provide the capability to compare the results of using different settings and algorithms in a consistent and unified way. The JRA is also providing tutorials and sample datasets to introduce the principles of image reconstruction and illustrate how to use the software products. We describe the design of the imaging tools, in particular the interface between the graphical user interface and the image reconstruction algorithms, and summarise the current status of their implementation.

  3. Creating user-friendly databases with Microsoft Access.

    Science.gov (United States)

    Schneider, Joanne Kraenzle; Schneider, Joseph F; Lorenz, Rebecca A

    2005-01-01

    Data entry can be tedious and is fraught with potential for errors that affect study findings. Researchers can minimise entry errors and streamline data entry by using some of the popular software packages on the market. Joanne Kraenzle Schneider and colleagues describe one way to create a user-friendly database that minimises entry errors by using Microsoft (MS) Access.

  4. A user-friendly modified pore-solid fractal model

    Science.gov (United States)

    Ding, Dian-Yuan; Zhao, Ying; Feng, Hao; Si, Bing-Cheng; Hill, Robert Lee

    2016-12-01

    The primary objective of this study was to evaluate a range of calculation points on water retention curves (WRC) instead of the singularity point at air-entry suction in the pore-solid fractal (PSF) model, which additionally considered the hysteresis effect based on the PSF theory. The modified pore-solid fractal (M-PSF) model was tested using 26 soil samples from Yangling on the Loess Plateau in China and 54 soil samples from the Unsaturated Soil Hydraulic Database. The derivation results showed that the M-PSF model is user-friendly and flexible for a wide range of calculation point options. This model theoretically describes the primary differences between the soil moisture desorption and the adsorption processes by the fractal dimensions. The M-PSF model demonstrated good performance particularly at the calculation points corresponding to the suctions from 100 cm to 1000 cm. Furthermore, the M-PSF model, used the fractal dimension of the particle size distribution, exhibited an accepted performance of WRC predictions for different textured soils when the suction values were ≥100 cm. To fully understand the function of hysteresis in the PSF theory, the role of allowable and accessible pores must be examined.

  5. Easyplot: An Interactive, User-Friendly Graphics Program.

    Science.gov (United States)

    1984-09-01

    AD-Ali58 779 EASYPLOT: AN INTERACTIVE USER-FRIENDLY GRPHICS PROGRAM 1/2 (U) NAVAL POSTGRADUATE SCHOOL MONTEREY CRRNWRN SP UNCLASSIFIED F/G 9/2 N...log) ar.J thzce-dime nsional (standard) .Graph correction and a-lteraticn dre possible with a ininimu~a oZ effort. The irogram was designed for the...thr-ougi, the design irocess to produce tie desired graph. The irograx is compieteiy int=r- act Ive. it prompts the user "or all ti’e necessary i;f

  6. On user-friendly interface construction for CACSD packages

    DEFF Research Database (Denmark)

    Ravn, Ole

    1989-01-01

    Some ideas that are used in the development of user-friendly interface for a computer-aided control system design (CACSD) package are presented. The concepts presented are integration and extensibility through the use of object-oriented programming, man-machine interface and user support using...... direct manipulation, and multiple views and multiple actions on objects in different domains. The use of multiple views and actions in combination with graphics enhances the user's ability to get an overview of the system to be designed. Good support for iteration is provided, and the short time between...... action and presentation allows the user to evaluate actions quickly. Object-oriented programming has been used to provide modularity and encapsulation...

  7. User-friendly design approach for analog layout design

    Science.gov (United States)

    Li, Yongfu; Lee, Zhao Chuan; Tripathi, Vikas; Perez, Valerio; Ong, Yoong Seang; Hui, Chiu Wing

    2017-03-01

    Analog circuits are sensitives to the changes in the layout environment conditions, manufacturing processes, and variations. This paper presents analog verification flow with five types of analogfocused layout constraint checks to assist engineers in identifying any potential device mismatch and layout drawing mistakes. Compared to several solutions, our approach only requires layout design, which is sufficient to recognize all the matched devices. Our approach simplifies the data preparation and allows seamless integration into the layout environment with minimum disruption to the custom layout flow. Our user-friendly analog verification flow provides the engineer with more confident with their layouts quality.

  8. A user friendly Lidar system based on LabVIEW

    Energy Technology Data Exchange (ETDEWEB)

    Andersson, Mats; Weibring, P.

    1996-09-01

    Mobile differential absorption lidar (DIAL) systems have been used for the last two decades. The lidar group in Lund has performed many DIAL measurements with a mobile lidar system which was first described in 1987. This report describes how that system was updated with the graphical programming language LabVIEW in order to get a user friendly system. The software controls the lidar system and analyses measurement data. The measurement results are shown as maps of species concentration. New electronics to support the new lidar program have also been installed. The report describes how all supporting electronics and the program work. A user manual for the new program is also given. 19 refs, 79 figs, 23 charts

  9. GEDI: a user-friendly toolbox for analysis of large-scale gene expression data.

    Science.gov (United States)

    Fujita, André; Sato, João R; Ferreira, Carlos E; Sogayar, Mari C

    2007-11-19

    Several mathematical and statistical methods have been proposed in the last few years to analyze microarray data. Most of those methods involve complicated formulas, and software implementations that require advanced computer programming skills. Researchers from other areas may experience difficulties when they attempting to use those methods in their research. Here we present an user-friendly toolbox which allows large-scale gene expression analysis to be carried out by biomedical researchers with limited programming skills. Here, we introduce an user-friendly toolbox called GEDI (Gene Expression Data Interpreter), an extensible, open-source, and freely-available tool that we believe will be useful to a wide range of laboratories, and to researchers with no background in Mathematics and Computer Science, allowing them to analyze their own data by applying both classical and advanced approaches developed and recently published by Fujita et al. GEDI is an integrated user-friendly viewer that combines the state of the art SVR, DVAR and SVAR algorithms, previously developed by us. It facilitates the application of SVR, DVAR and SVAR, further than the mathematical formulas present in the corresponding publications, and allows one to better understand the results by means of available visualizations. Both running the statistical methods and visualizing the results are carried out within the graphical user interface, rendering these algorithms accessible to the broad community of researchers in Molecular Biology.

  10. User-friendly software for modeling collective spin wave excitations

    Science.gov (United States)

    Hahn, Steven; Peterson, Peter; Fishman, Randy; Ehlers, Georg

    There exists a great need for user-friendly, integrated software that assists in the scientific analysis of collective spin wave excitations measured with inelastic neutron scattering. SpinWaveGenie is a C + + software library that simplifies the modeling of collective spin wave excitations, allowing scientists to analyze neutron scattering data with sophisticated models fast and efficiently. Furthermore, one can calculate the four-dimensional scattering function S(Q,E) to directly compare and fit calculations to experimental measurements. Its generality has been both enhanced and verified through successful modeling of a wide array of magnetic materials. Recently, we have spent considerable effort transforming SpinWaveGenie from an early prototype to a high quality free open source software package for the scientific community. S.E.H. acknowledges support by the Laboratory's Director's fund, ORNL. Work was sponsored by the Division of Scientific User Facilities, Office of Basic Energy Sciences, US Department of Energy, under Contract No. DE-AC05-00OR22725 with UT-Battelle, LLC.

  11. Calibrated user-friendly reverse transcriptase-PCR assay

    DEFF Research Database (Denmark)

    Bor, M V; Sørensen, B S; Rammer, P

    1998-01-01

    We report a competitive reverse transcriptase-PCR (RT-PCR) assay and a calibrated user-friendly RT-PCR assay (CURT-PCR) for epidermal growth factor receptor (EGFR) mRNA. A calibrator was prepared from isolated rat liver RNA, and the amount of EGFR mRNA was determined by competitive RT-PCR. In CUR...... and to accept or reject the results according to existing rules for quality assurance....... and the corresponding RNA internal standard. Competitive RT-PCR and CURT-PCR were used for rat liver samples from 21 different animals. Comparable results were obtained by the two methods. The imprecision of the CURT-PCR method was 8% (n = 20), and the imprecision of the traditional competitive RT-PCR was 16% (n = 17......). We conclude that the CURT-PCR method developed is suitable for routine applications such as quantitation of EGFR expression in tumor biopsies. The imprecision is relatively low. Furthermore, the use of a calibration curve makes it possible to analyze a large number of samples in one analytical run...

  12. MADANALYSIS 5, a user-friendly framework for collider phenomenology

    Science.gov (United States)

    Conte, Eric; Fuks, Benjamin; Serret, Guillaume

    2013-01-01

    We present MADANALYSIS 5, a new framework for phenomenological investigations at particle colliders. Based on a C++ kernel, this program allows us to efficiently perform, in a straightforward and user-friendly fashion, sophisticated physics analyses of event files such as those generated by a large class of Monte Carlo event generators. MADANALYSIS 5 comes with two modes of running. The first one, easier to handle, uses the strengths of a powerful PYTHON interface in order to implement physics analyses by means of a set of intuitive commands. The second one requires one to implement the analyses in the C++ programming language, directly within the core of the analysis framework. This opens unlimited possibilities concerning the level of complexity which can be reached, being only limited by the programming skills and the originality of the user. Program summaryProgram title: MadAnalysis 5 Catalogue identifier: AENO_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AENO_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Permission to use, copy, modify and distribute this program is granted under the terms of the GNU General Public License. No. of lines in distributed program, including test data, etc.: 31087 No. of bytes in distributed program, including test data, etc.: 399105 Distribution format: tar.gz Programming language: PYTHON, C++. Computer: All platforms on which Python version 2.7, Root version 5.27 and the g++ compiler are available. Compatibility with newer versions of these programs is also ensured. However, the Python version must be below version 3.0. Operating system: Unix, Linux and Mac OS operating systems on which the above-mentioned versions of Python and Root, as well as g++, are available. Classification: 11.1. External routines: ROOT (http://root.cern.ch/drupal/) Nature of problem: Implementing sophisticated phenomenological analyses in high-energy physics through a

  13. A User-Friendly Dark Energy Model Generator

    CERN Document Server

    Hinton, Kyle A; Huterer, Dragan

    2015-01-01

    We provide software with a graphical user interface to calculate the phenomenology of a wide class of dark energy models featuring multiple scalar fields. The user chooses a subclass of models and, if desired, initial conditions, or else a range of initial parameters for Monte Carlo. The code calculates the energy density of components in the universe, the equation of state of dark energy, and the linear growth of density perturbations, all as a function of redshift and scale factor. The output also includes an approximate conversion into the average equation of state, as well as the common $(w_0, w_a)$ parametrization. The code is available here: http://github.com/kahinton/Dark-Energy-UI-and-MC

  14. Sensor Network-Based and User-Friendly User Location Discovery for Future Smart Homes.

    Science.gov (United States)

    Ahvar, Ehsan; Lee, Gyu Myoung; Han, Son N; Crespi, Noel; Khan, Imran

    2016-06-27

    User location is crucial context information for future smart homes where many location based services will be proposed. This location necessarily means that User Location Discovery (ULD) will play an important role in future smart homes. Concerns about privacy and the need to carry a mobile or a tag device within a smart home currently make conventional ULD systems uncomfortable for users. Future smart homes will need a ULD system to consider these challenges. This paper addresses the design of such a ULD system for context-aware services in future smart homes stressing the following challenges: (i) users' privacy; (ii) device-/tag-free; and (iii) fault tolerance and accuracy. On the other hand, emerging new technologies, such as the Internet of Things, embedded systems, intelligent devices and machine-to-machine communication, are penetrating into our daily life with more and more sensors available for use in our homes. Considering this opportunity, we propose a ULD system that is capitalizing on the prevalence of sensors for the home while satisfying the aforementioned challenges. The proposed sensor network-based and user-friendly ULD system relies on different types of inexpensive sensors, as well as a context broker with a fuzzy-based decision-maker. The context broker receives context information from different types of sensors and evaluates that data using the fuzzy set theory. We demonstrate the performance of the proposed system by illustrating a use case, utilizing both an analytical model and simulation.

  15. Sensor Network-Based and User-Friendly User Location Discovery for Future Smart Homes

    Directory of Open Access Journals (Sweden)

    Ehsan Ahvar

    2016-06-01

    Full Text Available User location is crucial context information for future smart homes where many location based services will be proposed. This location necessarily means that User Location Discovery (ULD will play an important role in future smart homes. Concerns about privacy and the need to carry a mobile or a tag device within a smart home currently make conventional ULD systems uncomfortable for users. Future smart homes will need a ULD system to consider these challenges. This paper addresses the design of such a ULD system for context-aware services in future smart homes stressing the following challenges: (i users’ privacy; (ii device-/tag-free; and (iii fault tolerance and accuracy. On the other hand, emerging new technologies, such as the Internet of Things, embedded systems, intelligent devices and machine-to-machine communication, are penetrating into our daily life with more and more sensors available for use in our homes. Considering this opportunity, we propose a ULD system that is capitalizing on the prevalence of sensors for the home while satisfying the aforementioned challenges. The proposed sensor network-based and user-friendly ULD system relies on different types of inexpensive sensors, as well as a context broker with a fuzzy-based decision-maker. The context broker receives context information from different types of sensors and evaluates that data using the fuzzy set theory. We demonstrate the performance of the proposed system by illustrating a use case, utilizing both an analytical model and simulation.

  16. Sensor Network-Based and User-Friendly User Location Discovery for Future Smart Homes

    Science.gov (United States)

    Ahvar, Ehsan; Lee, Gyu Myoung; Han, Son N.; Crespi, Noel; Khan, Imran

    2016-01-01

    User location is crucial context information for future smart homes where many location based services will be proposed. This location necessarily means that User Location Discovery (ULD) will play an important role in future smart homes. Concerns about privacy and the need to carry a mobile or a tag device within a smart home currently make conventional ULD systems uncomfortable for users. Future smart homes will need a ULD system to consider these challenges. This paper addresses the design of such a ULD system for context-aware services in future smart homes stressing the following challenges: (i) users’ privacy; (ii) device-/tag-free; and (iii) fault tolerance and accuracy. On the other hand, emerging new technologies, such as the Internet of Things, embedded systems, intelligent devices and machine-to-machine communication, are penetrating into our daily life with more and more sensors available for use in our homes. Considering this opportunity, we propose a ULD system that is capitalizing on the prevalence of sensors for the home while satisfying the aforementioned challenges. The proposed sensor network-based and user-friendly ULD system relies on different types of inexpensive sensors, as well as a context broker with a fuzzy-based decision-maker. The context broker receives context information from different types of sensors and evaluates that data using the fuzzy set theory. We demonstrate the performance of the proposed system by illustrating a use case, utilizing both an analytical model and simulation. PMID:27355951

  17. A user friendly interface for microwave tomography enhanced GPR surveys

    Science.gov (United States)

    Catapano, Ilaria; Affinito, Antonio; Soldovieri, Francesco

    2013-04-01

    Ground Penetrating Radar (GPR) systems are nowadays widely used in civil applications among which structural monitoring is one of the most critical issues due to its importance in terms of risks prevents and cost effective management of the structure itself. Despite GPR systems are assessed devices, there is a continuous interest towards their optimization, which involves both hardware and software aspects, with the common final goal to achieve accurate and highly informative images while keeping as low as possible difficulties and times involved in on field surveys. As far as data processing is concerned, one of the key aims is the development of imaging approaches capable of providing images easily interpretable by not expert users while keeping feasible the requirements in terms of computational resources. To satisfy this request or at least improve the reconstruction capabilities of data processing tools actually available in commercial GPR systems, microwave tomographic approaches based on the Born approximation have been developed and tested in several practical conditions, such as civil and archeological investigations, sub-service monitoring, security surveys and so on [1-3]. However, the adoption of these approaches is subjected to the involvement of expert workers, which have to be capable of properly managing the gathered data and their processing, which involves the solution of a linear inverse scattering problem. In order to overcome this drawback, aim of this contribution is to present an end-user friendly software interface that makes possible a simple management of the microwave tomographic approaches. In particular, the proposed interface allows us to upload both synthetic and experimental data sets saved in .txt, .dt and .dt1 formats, to perform all the steps needed to obtain tomographic images and to display raw-radargrams, intermediate and final results. By means of the interface, the users can apply time gating, back-ground removal or both to

  18. Friends

    Institute of Scientific and Technical Information of China (English)

    邝群

    2002-01-01

    A life without a friend is a life without a sun. This is no doubt a truthful saying. Everybody needs friends. Without a friend, you will feel lonely and sad. Suppose you are in trouble , whom will you turn to for help if yo have no friends ?So it is necessary for all of us to make friends.

  19. A user-friendly phytoremediation database: creating the searchable database, the users, and the broader implications.

    Science.gov (United States)

    Famulari, Stevie; Witz, Kyla

    2015-01-01

    Designers, students, teachers, gardeners, farmers, landscape architects, architects, engineers, homeowners, and others have uses for the practice of phytoremediation. This research looks at the creation of a phytoremediation database which is designed for ease of use for a non-scientific user, as well as for students in an educational setting ( http://www.steviefamulari.net/phytoremediation ). During 2012, Environmental Artist & Professor of Landscape Architecture Stevie Famulari, with assistance from Kyla Witz, a landscape architecture student, created an online searchable database designed for high public accessibility. The database is a record of research of plant species that aid in the uptake of contaminants, including metals, organic materials, biodiesels & oils, and radionuclides. The database consists of multiple interconnected indexes categorized into common and scientific plant name, contaminant name, and contaminant type. It includes photographs, hardiness zones, specific plant qualities, full citations to the original research, and other relevant information intended to aid those designing with phytoremediation search for potential plants which may be used to address their site's need. The objective of the terminology section is to remove uncertainty for more inexperienced users, and to clarify terms for a more user-friendly experience. Implications of the work, including education and ease of browsing, as well as use of the database in teaching, are discussed.

  20. PRUB: A Privacy Protection Friend Recommendation System Based on User Behavior

    Directory of Open Access Journals (Sweden)

    Wei Jiang

    2016-01-01

    Full Text Available The fast developing social network is a double-edged sword. It remains a serious problem to provide users with excellent mobile social network services as well as protecting privacy data. Most popular social applications utilize behavior of users to build connection with people having similar behavior, thus improving user experience. However, many users do not want to share their certain behavioral information to the recommendation system. In this paper, we aim to design a secure friend recommendation system based on the user behavior, called PRUB. The system proposed aims at achieving fine-grained recommendation to friends who share some same characteristics without exposing the actual user behavior. We utilized the anonymous data from a Chinese ISP, which records the user browsing behavior, for 3 months to test our system. The experiment result shows that our system can achieve a remarkable recommendation goal and, at the same time, protect the privacy of the user behavior information.

  1. SimArray: a user-friendly and user-configurable microarray design tool

    Directory of Open Access Journals (Sweden)

    Meadows Lisa A

    2006-03-01

    Full Text Available Abstract Background Microarrays were first developed to assess gene expression but are now also used to map protein-binding sites and to assess allelic variation between individuals. Regardless of the intended application, efficient production and appropriate array design are key determinants of experimental success. Inefficient production can make larger-scale studies prohibitively expensive, whereas poor array design makes normalisation and data analysis problematic. Results We have developed a user-friendly tool, SimArray, which generates a randomised spot layout, computes a maximum meta-grid area, and estimates the print time, in response to user-specified design decisions. Selected parameters include: the number of probes to be printed; the microtitre plate format; the printing pin configuration, and the achievable spot density. SimArray is compatible with all current robotic spotters that employ 96-, 384- or 1536-well microtitre plates, and can be configured to reflect most production environments. Print time and maximum meta-grid area estimates facilitate evaluation of each array design for its suitability. Randomisation of the spot layout facilitates correction of systematic biases by normalisation. Conclusion SimArray is intended to help both established researchers and those new to the microarray field to develop microarray designs with randomised spot layouts that are compatible with their specific production environment. SimArray is an open-source program and is available from http://www.flychip.org.uk/SimArray/.

  2. A user-friendly web portal for T-Coffee on supercomputers

    Directory of Open Access Journals (Sweden)

    Koetsier Jos

    2011-05-01

    Full Text Available Abstract Background Parallel T-Coffee (PTC was the first parallel implementation of the T-Coffee multiple sequence alignment tool. It is based on MPI and RMA mechanisms. Its purpose is to reduce the execution time of the large-scale sequence alignments. It can be run on distributed memory clusters allowing users to align data sets consisting of hundreds of proteins within a reasonable time. However, most of the potential users of this tool are not familiar with the use of grids or supercomputers. Results In this paper we show how PTC can be easily deployed and controlled on a super computer architecture using a web portal developed using Rapid. Rapid is a tool for efficiently generating standardized portlets for a wide range of applications and the approach described here is generic enough to be applied to other applications, or to deploy PTC on different HPC environments. Conclusions The PTC portal allows users to upload a large number of sequences to be aligned by the parallel version of TC that cannot be aligned by a single machine due to memory and execution time constraints. The web portal provides a user-friendly solution.

  3. A user-friendly web portal for T-Coffee on supercomputers.

    Science.gov (United States)

    Rius, Josep; Cores, Fernando; Solsona, Francesc; van Hemert, Jano I; Koetsier, Jos; Notredame, Cedric

    2011-05-12

    Parallel T-Coffee (PTC) was the first parallel implementation of the T-Coffee multiple sequence alignment tool. It is based on MPI and RMA mechanisms. Its purpose is to reduce the execution time of the large-scale sequence alignments. It can be run on distributed memory clusters allowing users to align data sets consisting of hundreds of proteins within a reasonable time. However, most of the potential users of this tool are not familiar with the use of grids or supercomputers. In this paper we show how PTC can be easily deployed and controlled on a super computer architecture using a web portal developed using Rapid. Rapid is a tool for efficiently generating standardized portlets for a wide range of applications and the approach described here is generic enough to be applied to other applications, or to deploy PTC on different HPC environments. The PTC portal allows users to upload a large number of sequences to be aligned by the parallel version of TC that cannot be aligned by a single machine due to memory and execution time constraints. The web portal provides a user-friendly solution.

  4. StochPy: a comprehensive, user-friendly tool for simulating stochastic biological processes.

    Directory of Open Access Journals (Sweden)

    Timo R Maarleveld

    Full Text Available Single-cell and single-molecule measurements indicate the importance of stochastic phenomena in cell biology. Stochasticity creates spontaneous differences in the copy numbers of key macromolecules and the timing of reaction events between genetically-identical cells. Mathematical models are indispensable for the study of phenotypic stochasticity in cellular decision-making and cell survival. There is a demand for versatile, stochastic modeling environments with extensive, preprogrammed statistics functions and plotting capabilities that hide the mathematics from the novice users and offers low-level programming access to the experienced user. Here we present StochPy (Stochastic modeling in Python, which is a flexible software tool for stochastic simulation in cell biology. It provides various stochastic simulation algorithms, SBML support, analyses of the probability distributions of molecule copy numbers and event waiting times, analyses of stochastic time series, and a range of additional statistical functions and plotting facilities for stochastic simulations. We illustrate the functionality of StochPy with stochastic models of gene expression, cell division, and single-molecule enzyme kinetics. StochPy has been successfully tested against the SBML stochastic test suite, passing all tests. StochPy is a comprehensive software package for stochastic simulation of the molecular control networks of living cells. It allows novice and experienced users to study stochastic phenomena in cell biology. The integration with other Python software makes StochPy both a user-friendly and easily extendible simulation tool.

  5. Creating the User-Friendly Library by Evaluating Patron Perception of Signage.

    Science.gov (United States)

    Bosman, Ellen; Rusinek, Carol

    1997-01-01

    Librarians at Indiana University Northwest Library surveyed patrons on how to make the library's collection and services more accessible by improving signage. Examines the effectiveness of signage to instruct users, reduce difficulties and fears, ameliorate negative experiences, and contribute to a user-friendly environment. (AEF)

  6. PRIDEViewer: a novel user-friendly interface to visualize PRIDE XML files.

    Science.gov (United States)

    Medina-Aunon, J Alberto; Carazo, José M; Albar, Juan Pablo

    2011-01-01

    Current standardization initiatives have greatly contributed to share the information derived by proteomics experiments. One of these initiatives is the XML-based repository PRIDE (PRoteomics IDEntification database), although an XML-based document does not appear to present a user-friendly view at the first glance. PRIDEViewer is a novel Java-based application that presents the information available in a PRIDE XML file in a user-friendly manner, facilitating the interaction among end users as well as the understanding and evaluation of the compiled information. PRIDEViewer is freely available at: http://proteo.cnb.csic.es/prideviewer/.

  7. ABSTRACTION FOCUSED SYSTEM FOR USER FRIENDLY INFORMATION HANDLING OVER WWW

    Directory of Open Access Journals (Sweden)

    Dr. Pushpa R. Suri

    2011-07-01

    Full Text Available The World Wide Web has become the medium of preference for the circulation of information by common man,teams, organizations, and social communities. Information computing is the fundamental mean by which web information is retrieved and distributed. Conventional information computing approaches continues to be the most common to search documents of potential relevance. But unfortunately these offer only an imperfect solution as many relevant documents may be missed in the crude search process. The search process is sharplyquery specific and the results blindly follow the terms entered. The proposed Abstraction Focused framework for improved information computing over web attempts to resolve this basic problem that stamps from the information needs of the diverse users from the web. It implements abstraction by defining different indicators for directing the user search interests. Results from experiments with Abstraction Focused System approve the success particularly in cases where different users have a defined boundary of the search over WWW.

  8. User-friendly chemistry takes center stage at ACS meeting

    Energy Technology Data Exchange (ETDEWEB)

    Pool, R.

    1992-09-11

    These days it seems that what chemistry needs more than anything else is a good p.r. agent. If you ask John or Joan Q. Public about the accomplishments of the chemical industry, chances are they'll mention Love Canal, CFCs destroying the ozone layer, or carcinogens in food. However, if the national meeting of the American Chemical Society in Washington, D.C., 2 weeks ago is any indication, chemists are working hard to fix the image problem. Nearly all of the two dozen press conferences held during the meeting focused on food, health topics, environment-friendly technology, or some other subject close to consumers' hearts. And the scientific talks themselves reflected the same interests, with sessions such as Environmental Successes in the Chemical Industry', Food Phytochemicals for Cancer Prevention', Chemistry of Electrophilic Metal Complexes', New Advances in Polyolefin Polymers', Zapping acid rain with microwaves.'

  9. User-Friendly Predictive Modeling of Greenhouse Gas (GHG) Fluxes and Carbon Storage in Tidal Wetlands

    Science.gov (United States)

    Ishtiaq, K. S.; Abdul-Aziz, O. I.

    2015-12-01

    We developed user-friendly empirical models to predict instantaneous fluxes of CO2 and CH4 from coastal wetlands based on a small set of dominant hydro-climatic and environmental drivers (e.g., photosynthetically active radiation, soil temperature, water depth, and soil salinity). The dominant predictor variables were systematically identified by applying a robust data-analytics framework on a wide range of possible environmental variables driving wetland greenhouse gas (GHG) fluxes. The method comprised of a multi-layered data-analytics framework, including Pearson correlation analysis, explanatory principal component and factor analyses, and partial least squares regression modeling. The identified dominant predictors were finally utilized to develop power-law based non-linear regression models to predict CO2 and CH4 fluxes under different climatic, land use (nitrogen gradient), tidal hydrology and salinity conditions. Four different tidal wetlands of Waquoit Bay, MA were considered as the case study sites to identify the dominant drivers and evaluate model performance. The study sites were dominated by native Spartina Alterniflora and characterized by frequent flooding and high saline conditions. The model estimated the potential net ecosystem carbon balance (NECB) both in gC/m2 and metric tonC/hectare by up-scaling the instantaneous predicted fluxes to the growing season and accounting for the lateral C flux exchanges between the wetlands and estuary. The entire model was presented in a single Excel spreadsheet as a user-friendly ecological engineering tool. The model can aid the development of appropriate GHG offset protocols for setting monitoring plans for tidal wetland restoration and maintenance projects. The model can also be used to estimate wetland GHG fluxes and potential carbon storage under various IPCC climate change and sea level rise scenarios; facilitating an appropriate management of carbon stocks in tidal wetlands and their incorporation into a

  10. A user-friendly forest model with a multiplicative mathematical structure: a Bayesian approach to calibration

    Directory of Open Access Journals (Sweden)

    M. Bagnara

    2014-10-01

    Full Text Available Forest models are being increasingly used to study ecosystem functioning, through the reproduction of carbon fluxes and productivity in very different forests all over the world. Over the last two decades, the need for simple and "easy to use" models for practical applications, characterized by few parameters and equations, has become clear, and some have been developed for this purpose. These models aim to represent the main drivers underlying forest ecosystem processes while being applicable to the widest possible range of forest ecosystems. Recently, it has also become clear that model performance should not be assessed only in terms of accuracy of estimations and predictions, but also in terms of estimates of model uncertainties. Therefore, the Bayesian approach has increasingly been applied to calibrate forest models, with the aim of estimating the uncertainty of their results, and of comparing their performances. Some forest models, considered to be user-friendly, rely on a multiplicative or quasi-multiplicative mathematical structure, which is known to cause problems during the calibration process, mainly due to high correlations between parameters. In a Bayesian framework using a Markov Chain Monte Carlo sampling this is likely to impair the reaching of a proper convergence of the chains and the sampling from the correct posterior distribution. Here we show two methods to reach proper convergence when using a forest model with a multiplicative structure, applying different algorithms with different number of iterations during the Markov Chain Monte Carlo or a two-steps calibration. The results showed that recently proposed algorithms for adaptive calibration do not confer a clear advantage over the Metropolis–Hastings Random Walk algorithm for the forest model used here. Moreover, the calibration remains time consuming and mathematically difficult, so advantages of using a fast and user-friendly model can be lost due to the calibration

  11. GMOseek: a user friendly tool for optimized GMO testing.

    Science.gov (United States)

    Morisset, Dany; Novak, Petra Kralj; Zupanič, Darko; Gruden, Kristina; Lavrač, Nada; Žel, Jana

    2014-08-01

    With the increasing pace of new Genetically Modified Organisms (GMOs) authorized or in pipeline for commercialization worldwide, the task of the laboratories in charge to test the compliance of food, feed or seed samples with their relevant regulations became difficult and costly. Many of them have already adopted the so called "matrix approach" to rationalize the resources and efforts used to increase their efficiency within a limited budget. Most of the time, the "matrix approach" is implemented using limited information and some proprietary (if any) computational tool to efficiently use the available data. The developed GMOseek software is designed to support decision making in all the phases of routine GMO laboratory testing, including the interpretation of wet-lab results. The tool makes use of a tabulated matrix of GM events and their genetic elements, of the laboratory analysis history and the available information about the sample at hand. The tool uses an optimization approach to suggest the most suited screening assays for the given sample. The practical GMOseek user interface allows the user to customize the search for a cost-efficient combination of screening assays to be employed on a given sample. It further guides the user to select appropriate analyses to determine the presence of individual GM events in the analyzed sample, and it helps taking a final decision regarding the GMO composition in the sample. GMOseek can also be used to evaluate new, previously unused GMO screening targets and to estimate the profitability of developing new GMO screening methods. The presented freely available software tool offers the GMO testing laboratories the possibility to select combinations of assays (e.g. quantitative real-time PCR tests) needed for their task, by allowing the expert to express his/her preferences in terms of multiplexing and cost. The utility of GMOseek is exemplified by analyzing selected food, feed and seed samples from a national reference

  12. Evaluation and comparison of classical interatomic potentials through a user-friendly interactive web-interface

    Science.gov (United States)

    Choudhary, Kamal; Congo, Faical Yannick P.; Liang, Tao; Becker, Chandler; Hennig, Richard G.; Tavazza, Francesca

    2017-01-01

    Classical empirical potentials/force-fields (FF) provide atomistic insights into material phenomena through molecular dynamics and Monte Carlo simulations. Despite their wide applicability, a systematic evaluation of materials properties using such potentials and, especially, an easy-to-use user-interface for their comparison is still lacking. To address this deficiency, we computed energetics and elastic properties of variety of materials such as metals and ceramics using a wide range of empirical potentials and compared them to density functional theory (DFT) as well as to experimental data, where available. The database currently consists of 3248 entries including energetics and elastic property calculations, and it is still increasing. We also include computational tools for convex-hull plots for DFT and FF calculations. The data covers 1471 materials and 116 force-fields. In addition, both the complete database and the software coding used in the process have been released for public use online (presently at http://www.ctcms.nist.gov/∼knc6/periodic.html) in a user-friendly way designed to enable further material design and discovery.

  13. Evaluation and comparison of classical interatomic potentials through a user-friendly interactive web-interface

    Science.gov (United States)

    Choudhary, Kamal; Congo, Faical Yannick P.; Liang, Tao; Becker, Chandler; Hennig, Richard G.; Tavazza, Francesca

    2017-01-01

    Classical empirical potentials/force-fields (FF) provide atomistic insights into material phenomena through molecular dynamics and Monte Carlo simulations. Despite their wide applicability, a systematic evaluation of materials properties using such potentials and, especially, an easy-to-use user-interface for their comparison is still lacking. To address this deficiency, we computed energetics and elastic properties of variety of materials such as metals and ceramics using a wide range of empirical potentials and compared them to density functional theory (DFT) as well as to experimental data, where available. The database currently consists of 3248 entries including energetics and elastic property calculations, and it is still increasing. We also include computational tools for convex-hull plots for DFT and FF calculations. The data covers 1471 materials and 116 force-fields. In addition, both the complete database and the software coding used in the process have been released for public use online (presently at http://www.ctcms.nist.gov/∼knc6/periodic.html) in a user-friendly way designed to enable further material design and discovery. PMID:28140407

  14. A user-friendly model for spray drying to aid pharmaceutical product development

    NARCIS (Netherlands)

    Grasmeijer, Niels; de Waard, Hans; Hinrichs, Wouter L J; Frijlink, Henderik W

    2013-01-01

    The aim of this study was to develop a user-friendly model for spray drying that can aid in the development of a pharmaceutical product, by shifting from a trial-and-error towards a quality-by-design approach. To achieve this, a spray dryer model was developed in commercial and open source spreadshe

  15. A Minicomputer Implementation of a Data Model Independent, User-Friendly Interface to Databases.

    Science.gov (United States)

    1982-12-15

    tutorial showing simple examples. The command language ia a non- procedural relational algebraic language which includes the most useful of the relational...to access and what his query is. AQERS will be a very useful, user-friendly tool. 4’ I 4 55 References 1. Cardenas , Alphonso F. Data Base Management

  16. eMODIS: A User-Friendly Data Source

    Science.gov (United States)

    Jenkerson, Calli; Maiersperger, Thomas; Schmidt, Gail

    2010-01-01

    , created daily with the most recent 7 days of acquisition, to users monitoring real-time vegetation conditions. eMODIS Alaska is not part of expedited processing, but does cover the Terra mission life (2000-present). A simple file transfer protocol (FTP) distribution site currently is enabled on the Internet for direct download of eMODIS products (ftp://emodisftp.cr.usgs.gov/eMODIS), with plans to expand into an interactive portal environment.

  17. A user-friendly modified pore-solid fractal model

    OpenAIRE

    Dian-yuan Ding; Ying Zhao; Hao Feng; Bing-cheng Si; Robert Lee Hill

    2016-01-01

    The primary objective of this study was to evaluate a range of calculation points on water retention curves (WRC) instead of the singularity point at air-entry suction in the pore-solid fractal (PSF) model, which additionally considered the hysteresis effect based on the PSF theory. The modified pore-solid fractal (M-PSF) model was tested using 26 soil samples from Yangling on the Loess Plateau in China and 54 soil samples from the Unsaturated Soil Hydraulic Database. The derivation results s...

  18. Development of a user-friendly interface version of the Salmonella source-attribution model

    DEFF Research Database (Denmark)

    Hald, Tine; Lund, Jan

    of questions, where the use of a classical quantitative risk assessment model (i.e. transmission models) would be impaired due to a lack of data and time limitations. As these models require specialist knowledge, it was requested by EFSA to develop a flexible user-friendly source attribution model for use...... with a user-manual, which is also part of this report. Users of the interface are recommended to read this report before starting using the interface to become familiar with the model principles and the mathematics behind, which is required in order to interpret the model results and assess the validity...

  19. The use of Graphic User Interface for development of a user-friendly CRS-Stack software

    Science.gov (United States)

    Sule, Rachmat; Prayudhatama, Dythia; Perkasa, Muhammad D.; Hendriyana, Andri; Fatkhan; Sardjito; Adriansyah

    2017-04-01

    The development of a user-friendly Common Reflection Surface (CRS) Stack software that has been built by implementing Graphical User Interface (GUI) is described in this paper. The original CRS-Stack software developed by WIT Consortium is compiled in the unix/linux environment, which is not a user-friendly software, so that a user must write the commands and parameters manually in a script file. Due to this limitation, the CRS-Stack become a non popular method, although applying this method is actually a promising way in order to obtain better seismic sections, which have better reflector continuity and S/N ratio. After obtaining successful results that have been tested by using several seismic data belong to oil companies in Indonesia, it comes to an idea to develop a user-friendly software in our own laboratory. Graphical User Interface (GUI) is a type of user interface that allows people to interact with computer programs in a better way. Rather than typing commands and module parameters, GUI allows the users to use computer programs in much simple and easy. Thus, GUI can transform the text-based interface into graphical icons and visual indicators. The use of complicated seismic unix shell script can be avoided. The Java Swing GUI library is used to develop this CRS-Stack GUI. Every shell script that represents each seismic process is invoked from Java environment. Besides developing interactive GUI to perform CRS-Stack processing, this CRS-Stack GUI is design to help geophysicists to manage a project with complex seismic processing procedures. The CRS-Stack GUI software is composed by input directory, operators, and output directory, which are defined as a seismic data processing workflow. The CRS-Stack processing workflow involves four steps; i.e. automatic CMP stack, initial CRS-Stack, optimized CRS-Stack, and CRS-Stack Supergather. Those operations are visualized in an informative flowchart with self explanatory system to guide the user inputting the

  20. You are Who You Know and How You Behave: Attribute Inference Attacks via Users' Social Friends and Behaviors

    CERN Document Server

    Gong, Neil Zhenqiang

    2016-01-01

    We propose new privacy attacks to infer attributes (e.g., locations, occupations, and interests) of online social network users. Our attacks leverage seemingly innocent user information that is publicly available in online social networks to infer missing attributes of targeted users. Given the increasing availability of (seemingly innocent) user information online, our results have serious implications for Internet privacy -- private attributes can be inferred from users' publicly available data unless we take steps to protect users from such inference attacks. To infer attributes of a targeted user, existing inference attacks leverage either the user's publicly available social friends or the user's behavioral records (e.g., the webpages that the user has liked on Facebook, the apps that the user has reviewed on Google Play), but not both. As we will show, such inference attacks achieve limited success rates. However, the problem becomes qualitatively different if we consider both social friends and behavio...

  1. A user-friendly model for spray drying to aid pharmaceutical product development.

    Science.gov (United States)

    Grasmeijer, Niels; de Waard, Hans; Hinrichs, Wouter L J; Frijlink, Henderik W

    2013-01-01

    The aim of this study was to develop a user-friendly model for spray drying that can aid in the development of a pharmaceutical product, by shifting from a trial-and-error towards a quality-by-design approach. To achieve this, a spray dryer model was developed in commercial and open source spreadsheet software. The output of the model was first fitted to the experimental output of a Büchi B-290 spray dryer and subsequently validated. The predicted outlet temperatures of the spray dryer model matched the experimental values very well over the entire range of spray dryer settings that were tested. Finally, the model was applied to produce glassy sugars by spray drying, an often used excipient in formulations of biopharmaceuticals. For the production of glassy sugars, the model was extended to predict the relative humidity at the outlet, which is not measured in the spray dryer by default. This extended model was then successfully used to predict whether specific settings were suitable for producing glassy trehalose and inulin by spray drying. In conclusion, a spray dryer model was developed that is able to predict the output parameters of the spray drying process. The model can aid the development of spray dried pharmaceutical products by shifting from a trial-and-error towards a quality-by-design approach.

  2. Alkahest NuclearBLAST : a user-friendly BLAST management and analysis system

    Directory of Open Access Journals (Sweden)

    Burke Mark

    2005-06-01

    Full Text Available Abstract Background - Sequencing of EST and BAC end datasets is no longer limited to large research groups. Drops in per-base pricing have made high throughput sequencing accessible to individual investigators. However, there are few options available which provide a free and user-friendly solution to the BLAST result storage and data mining needs of biologists. Results - Here we describe NuclearBLAST, a batch BLAST analysis, storage and management system designed for the biologist. It is a wrapper for NCBI BLAST which provides a user-friendly web interface which includes a request wizard and the ability to view and mine the results. All BLAST results are stored in a MySQL database which allows for more advanced data-mining through supplied command-line utilities or direct database access. NuclearBLAST can be installed on a single machine or clustered amongst a number of machines to improve analysis throughput. NuclearBLAST provides a platform which eases data-mining of multiple BLAST results. With the supplied scripts, the program can export data into a spreadsheet-friendly format, automatically assign Gene Ontology terms to sequences and provide bi-directional best hits between two datasets. Users with SQL experience can use the database to ask even more complex questions and extract any subset of data they require. Conclusion - This tool provides a user-friendly interface for requesting, viewing and mining of BLAST results which makes the management and data-mining of large sets of BLAST analyses tractable to biologists.

  3. HBV light - A user-friendly catchment-runoff-model software

    Science.gov (United States)

    Seibert, J.; Vis, M.; Käser, D.

    2012-04-01

    Conceptual models are frequently used for catchment hydrology studies. Here we present a new version of the HBV model, which has been programmed in Visual Basic .NET. This software provides a user-friendly version which is especially useful for education. Different functionalities like an automatic calibration and the possibility to perform Monte Carlo runs make the software also interesting for research projects. Furthermore, a command line version is suitable for automating modeling procedures and for coupling with software such as PEST.

  4. USTOPIA Requirements -- Thoughts on a User-friendly System for Transformation Of Programs In Abstracto

    OpenAIRE

    Boiten, Eerke Albert; van den Brand, M.G.J.; Diepen, N.W.P.; Koster, C.H.A.; Partsch, H.A.; Völker, N.

    1992-01-01

    E.A. Boiten , http://adam.fwi.uva.nl/~markvdb/ , http://www.sci.kun.nl/cgi-bin-thalia/smoelfind?medewerkers/niekd.html , http://www.sci.kun.nl/cgi-bin-thalia/smoelfind?medewerkers/kees.html , http://www.informatik.uni-ulm.de/pm/mitarbeiter/helmuth.html & http://www.fernuni-hagen.de/DVT/Mitarbeiter/voelker.html : USTOPIA Requirements - Thoughts on a User-friendly System for Transformation Of Programs In Abstracto Transformational programming is a program development method which is usually...

  5. USTOPIA Requirements -- Thoughts on a User-friendly System for Transformation Of Programs In Abstracto

    OpenAIRE

    Boiten, Eerke Albert; van den Brand, M.G.J.; Diepen, N.W.P. van; Koster, C.H.A.; Partsch, H.A.; Völker, N.

    1992-01-01

    E.A. Boiten , http://adam.fwi.uva.nl/~markvdb/ , http://www.sci.kun.nl/cgi-bin-thalia/smoelfind?medewerkers/niekd.html , http://www.sci.kun.nl/cgi-bin-thalia/smoelfind?medewerkers/kees.html , http://www.informatik.uni-ulm.de/pm/mitarbeiter/helmuth.html & http://www.fernuni-hagen.de/DVT/Mitarbeiter/voelker.html : USTOPIA Requirements - Thoughts on a User-friendly System for Transformation Of Programs In Abstracto Transformational programming is a program development method which is usually...

  6. Synesteer Final Report for "User Friendly Steering and Diagnostics for Modeling Heavy Ion Fusion Accelerators"

    Energy Technology Data Exchange (ETDEWEB)

    Stoltz, Peter; Dechow, Doug; Kruger, Scott; Granger, Brian

    2007-10-15

    The goal accomplished in this project was to improve the Synergia code by improving the integration of the Impact space charge algorithms into Synergia and improving the graphical user interface for analyzing results. We accomplished five tasks along these lines: (i) a refactoring of the Impact space charge algorithm to make it more accessible by other codes, (ii) development of the Forthon interface between Impact and Python, (iii) implementation of a Python-MPI interface to allow parallel space charge calculation, (iv) a new user-friendly interface for analyzing Synergia results, and (v) a toolkit for doing parallel analysis of Synergia results.

  7. SimWall: a practical user-friendly stereo tiled display wall system

    Institute of Scientific and Technical Information of China (English)

    XIE Li-jun; ZHENG Yao; YANG Ting-jun; GAO Wen-xuan; PAN Ning-he

    2007-01-01

    Sim Wall is a user-friendly, stereo tiled display wall system composed of 18 commodity projectors operated by a Linux graphics cluster. Collaborating together, these projectors work as a single logical display capable of giving a high-resolution show,large-scale, and passive stereo scene. In order to avoid tedious system setup and maintenance, software-based automatic geometry and photometric calibration are used. The software calibration is integrated to the system seamlessly by an on-card transform method and is transparent to users. To end-users, Sim Wall works just as a common PC, but provides super computing, rendering and displaying ability. In addition, Sim Wall has stereoscopic function that gives users a semi-immersive experience in polarized passive way. This paper presents system architecture, implementation, and other technical issues such as hardware constraints,projectors alignment, geometry and photometric calibration, implementation of passive stereo, and development of overall software environment.

  8. SKIRT: An advanced dust radiative transfer code with a user-friendly architecture

    Science.gov (United States)

    Camps, P.; Baes, M.

    2015-03-01

    We discuss the architecture and design principles that underpin the latest version of SKIRT, a state-of-the-art open source code for simulating continuum radiation transfer in dusty astrophysical systems, such as spiral galaxies and accretion disks. SKIRT employs the Monte Carlo technique to emulate the relevant physical processes including scattering, absorption and emission by the dust. The code features a wealth of built-in geometries, radiation source spectra, dust characterizations, dust grids, and detectors, in addition to various mechanisms for importing snapshots generated by hydrodynamical simulations. The configuration for a particular simulation is defined at run-time through a user-friendly interface suitable for both occasional and power users. These capabilities are enabled by careful C++ code design. The programming interfaces between components are well defined and narrow. Adding a new feature is usually as simple as adding another class; the user interface automatically adjusts to allow configuring the new options. We argue that many scientific codes, like SKIRT, can benefit from careful object-oriented design and from a friendly user interface, even if it is not a graphical user interface.

  9. A user friendly method to isolate and single spore the fungi Magnaporthe oryzae and Magnaporthe grisea obtained from diseased field samples

    Science.gov (United States)

    The fungus Magnaporthe oryzae is the causal agent for a wide range of plant diseases including diseases of rice, wheat, rye grass, turfgrass and pearl millet. A simple robust procedure for fungal isolation is not publicly available. In the present study, a user friendly method was developed to iso...

  10. EPIPOI: A user-friendly analytical tool for the extraction and visualization of temporal parameters from epidemiological time series

    Directory of Open Access Journals (Sweden)

    Alonso Wladimir J

    2012-11-01

    Full Text Available Abstract Background There is an increasing need for processing and understanding relevant information generated by the systematic collection of public health data over time. However, the analysis of those time series usually requires advanced modeling techniques, which are not necessarily mastered by staff, technicians and researchers working on public health and epidemiology. Here a user-friendly tool, EPIPOI, is presented that facilitates the exploration and extraction of parameters describing trends, seasonality and anomalies that characterize epidemiological processes. It also enables the inspection of those parameters across geographic regions. Although the visual exploration and extraction of relevant parameters from time series data is crucial in epidemiological research, until now it had been largely restricted to specialists. Methods EPIPOI is freely available software developed in Matlab (The Mathworks Inc that runs both on PC and Mac computers. Its friendly interface guides users intuitively through useful comparative analyses including the comparison of spatial patterns in temporal parameters. Results EPIPOI is able to handle complex analyses in an accessible way. A prototype has already been used to assist researchers in a variety of contexts from didactic use in public health workshops to the main analytical tool in published research. Conclusions EPIPOI can assist public health officials and students to explore time series data using a broad range of sophisticated analytical and visualization tools. It also provides an analytical environment where even advanced users can benefit by enabling a higher degree of control over model assumptions, such as those associated with detecting disease outbreaks and pandemics.

  11. DockingApp: a user friendly interface for facilitated docking simulations with AutoDock Vina

    Science.gov (United States)

    Di Muzio, Elena; Toti, Daniele; Polticelli, Fabio

    2017-02-01

    Molecular docking is a powerful technique that helps uncover the structural and energetic bases of the interaction between macromolecules and substrates, endogenous and exogenous ligands, and inhibitors. Moreover, this technique plays a pivotal role in accelerating the screening of large libraries of compounds for drug development purposes. The need to promote community-driven drug development efforts, especially as far as neglected diseases are concerned, calls for user-friendly tools to allow non-expert users to exploit the full potential of molecular docking. Along this path, here is described the implementation of DockingApp, a freely available, extremely user-friendly, platform-independent application for performing docking simulations and virtual screening tasks using AutoDock Vina. DockingApp sports an intuitive graphical user interface which greatly facilitates both the input phase and the analysis of the results, which can be visualized in graphical form using the embedded JMol applet. The application comes with the DrugBank set of more than 1400 ready-to-dock, FDA-approved drugs, to facilitate virtual screening and drug repurposing initiatives. Furthermore, other databases of compounds such as ZINC, available also in AutoDock format, can be readily and easily plugged in.

  12. DockingApp: a user friendly interface for facilitated docking simulations with AutoDock Vina.

    Science.gov (United States)

    Di Muzio, Elena; Toti, Daniele; Polticelli, Fabio

    2017-02-01

    Molecular docking is a powerful technique that helps uncover the structural and energetic bases of the interaction between macromolecules and substrates, endogenous and exogenous ligands, and inhibitors. Moreover, this technique plays a pivotal role in accelerating the screening of large libraries of compounds for drug development purposes. The need to promote community-driven drug development efforts, especially as far as neglected diseases are concerned, calls for user-friendly tools to allow non-expert users to exploit the full potential of molecular docking. Along this path, here is described the implementation of DockingApp, a freely available, extremely user-friendly, platform-independent application for performing docking simulations and virtual screening tasks using AutoDock Vina. DockingApp sports an intuitive graphical user interface which greatly facilitates both the input phase and the analysis of the results, which can be visualized in graphical form using the embedded JMol applet. The application comes with the DrugBank set of more than 1400 ready-to-dock, FDA-approved drugs, to facilitate virtual screening and drug repurposing initiatives. Furthermore, other databases of compounds such as ZINC, available also in AutoDock format, can be readily and easily plugged in.

  13. DockingApp: a user friendly interface for facilitated docking simulations with AutoDock Vina

    Science.gov (United States)

    Di Muzio, Elena; Toti, Daniele; Polticelli, Fabio

    2017-01-01

    Molecular docking is a powerful technique that helps uncover the structural and energetic bases of the interaction between macromolecules and substrates, endogenous and exogenous ligands, and inhibitors. Moreover, this technique plays a pivotal role in accelerating the screening of large libraries of compounds for drug development purposes. The need to promote community-driven drug development efforts, especially as far as neglected diseases are concerned, calls for user-friendly tools to allow non-expert users to exploit the full potential of molecular docking. Along this path, here is described the implementation of DockingApp, a freely available, extremely user-friendly, platform-independent application for performing docking simulations and virtual screening tasks using AutoDock Vina. DockingApp sports an intuitive graphical user interface which greatly facilitates both the input phase and the analysis of the results, which can be visualized in graphical form using the embedded JMol applet. The application comes with the DrugBank set of more than 1400 ready-to-dock, FDA-approved drugs, to facilitate virtual screening and drug repurposing initiatives. Furthermore, other databases of compounds such as ZINC, available also in AutoDock format, can be readily and easily plugged in.

  14. SKIRT: an Advanced Dust Radiative Transfer Code with a User-Friendly Architecture

    CERN Document Server

    Camps, Peter

    2014-01-01

    We discuss the architecture and design principles that underpin the latest version of SKIRT, a state-of-the-art open source code for simulating continuum radiation transfer in dusty astrophysical systems, such as spiral galaxies and accretion disks. SKIRT employs the Monte Carlo technique to emulate the relevant physical processes including scattering, absorption and emission by the dust. The code features a wealth of built-in geometries, radiation source spectra, dust characterizations, dust grids, and detectors, in addition to various mechanisms for importing snapshots generated by hydrodynamical simulations. The configuration for a particular simulation is defined at run-time through a user-friendly interface suitable for both occasional and power users. These capabilities are enabled by careful C++ code design. The programming interfaces between components are well defined and narrow. Adding a new feature is usually as simple as adding another class; the user interface automatically adjusts to allow confi...

  15. A Full-Featured User Friendly CO{sub 2}-EOR and Sequestration Planning Software

    Energy Technology Data Exchange (ETDEWEB)

    Savage, Bill

    2013-11-30

    A Full-Featured, User Friendly CO{sub 2}-EOR and Sequestration Planning Software This project addressed the development of an integrated software solution that includes a graphical user interface, numerical simulation, visualization tools and optimization processes for reservoir simulation modeling of CO{sub 2}-EOR. The objective was to assist the industry in the development of domestic energy resources by expanding the application of CO{sub 2}-EOR technologies, and ultimately to maximize the CO{sub 2} sequestration capacity of the U.S. The software resulted in a field-ready application for the industry to address the current CO{sub 2}-EOR technologies. The software has been made available to the public without restrictions and with user friendly operating documentation and tutorials. The software (executable only) can be downloaded from NITEC’s website at www.nitecllc.com. This integrated solution enables the design, optimization and operation of CO{sub 2}-EOR processes for small and mid-sized operators, who currently cannot afford the expensive, time intensive solutions that the major oil companies enjoy. Based on one estimate, small oil fields comprise 30% of the of total economic resource potential for the application of CO{sub 2}-EOR processes in the U.S. This corresponds to 21.7 billion barrels of incremental, technically recoverable oil using the current “best practices”, and 31.9 billion barrels using “next-generation” CO{sub 2}-EOR techniques. The project included a Case Study of a prospective CO{sub 2}-EOR candidate field in Wyoming by a small independent, Linc Energy Petroleum Wyoming, Inc. NITEC LLC has an established track record of developing innovative and user friendly software. The Principle Investigator is an experienced manager and engineer with expertise in software development, numerical techniques, and GUI applications. Unique, presently-proprietary NITEC technologies have been integrated into this application to further its ease of

  16. Scalable and user friendly user interface for time-series analytics for OpenTSDB

    OpenAIRE

    Martín Muñoz, Roberto

    2014-01-01

    OpenTSDB is a fast and reliable database used worldwide. While it has numerous advantages, its current web user interface is simplistic and not interactive, wasting the time that takes to perform a specific task . This thesis focuses on the implementation of a more reliable and interactive architecture using a Model, View, Controller architecture while considering visual analytics, NodeJS, websockets, Python, and R. The nodejs server is proposed as a solution. It has four di...

  17. User-friendly cognitive training for the elderly: a technical report.

    Science.gov (United States)

    Boquete, Luciano; Rodríguez-Ascariz, José Manuel; Amo-Usanos, Carlos; Martínez-Arribas, Alejandro; Amo-Usanos, Javier; Otón, Salvador

    2011-01-01

    This article presents a system that implements a cognitive training program in users' homes. The system comprises various applications designed to create a daily brain-fitness regime. The proposed mental training system uses television and a remote control specially designed for the elderly. This system integrates Java applications to promote brain-fitness training in three areas: arithmetic, memory, and idea association. The system comprises the following: Standard television set, simplified wireless remote control, black box (system's core hardware and software), brain-fitness games (language Java), and Wi-Fi-enabled Internet-connected router. All data from the user training sessions are monitored through a control center. This control center analyzes the evolution of the user and the proper performance of the system during the test. The implemented system has been tested by six healthy volunteers. The results for this user group demonstrated the accessibility and usability of the system in a controlled real environment. The impressions of the users were very favorable, and they reported high adaptability to the system. The mean score for usability and accessibility assigned by the users was 3.56 out of 5 points. The operation stress test (over 200 h) was successful. The proposed system was used to implement a cognitive training program in users' homes, which was developed to be a low-cost tool with a high degree of user interactivity. The results of this preliminary study indicate that this user-friendly system could be adopted as a form of cognitive training for the elderly.

  18. Design and Implementation of a User Friendly OpenModelica Graphical Connection Editor

    OpenAIRE

    Asghar, Syed Adeel; Tariq, Sonia

    2010-01-01

    OpenModelica (www.openmodelica.org) is an open-source Modelica-based modeling and simulation environment intended for industrial as well as academic usage. Its long-term development is supported by a non-profit organization – the Open Source Modelica Consortium OSMC, where Linköping University is a member.The main reason behind this thesis was the need for a user friendly, efficient and modular OpenModelica graphical connection editor. The already existing open source editors were either text...

  19. PIVlab – Towards User-friendly, Affordable and Accurate Digital Particle Image Velocimetry in MATLAB

    Directory of Open Access Journals (Sweden)

    William Thielicke

    2014-10-01

    Full Text Available Digital particle image velocimetry (DPIV is a non-intrusive analysis technique that is very popular for mapping flows quantitatively. To get accurate results, in particular in complex flow fields, a number of challenges have to be faced and solved: The quality of the flow measurements is affected by computational details such as image pre-conditioning, sub-pixel peak estimators, data validation procedures, interpolation algorithms and smoothing methods. The accuracy of several algorithms was determined and the best performing methods were implemented in a user-friendly open-source tool for performing DPIV flow analysis in Matlab.

  20. A user-friendly tool for medical-related patent retrieval.

    Science.gov (United States)

    Pasche, Emilie; Gobeill, Julien; Teodoro, Douglas; Gaudinat, Arnaud; Vishnyakova, Dina; Lovis, Christian; Ruch, Patrick

    2012-01-01

    Health-related information retrieval is complicated by the variety of nomenclatures available to name entities, since different communities of users will use different ways to name a same entity. We present in this report the development and evaluation of a user-friendly interactive Web application aiming at facilitating health-related patent search. Our tool, called TWINC, relies on a search engine tuned during several patent retrieval competitions, enhanced with intelligent interaction modules, such as chemical query, normalization and expansion. While the functionality of related article search showed promising performances, the ad hoc search results in fairly contrasted results. Nonetheless, TWINC performed well during the PatOlympics competition and was appreciated by intellectual property experts. This result should be balanced by the limited evaluation sample. We can also assume that it can be customized to be applied in corporate search environments to process domain and company-specific vocabularies, including non-English literature and patents reports.

  1. MadAnalysis 5, a user-friendly framework for collider phenomenology

    CERN Document Server

    Conte, Eric; Serret, Guillaume

    2012-01-01

    We present MadAnalysis 5, a new framework for phenomenological investigations at particle colliders. Based on a C++ kernel, this program allows to efficiently perform, in a straightforward and user-friendly fashion, sophisticated physics analyses of event files such as those generated by a large class of Monte Carlo event generators. MadAnalysis 5 comes with two modes of running. The first one, easier to handle, uses the strengths of a powerful Python interface in order to implement physics analyses by means of a set of intuitive commands. The second one requires to implement the analyses in the C++ programming language, directly within the core of the analysis framework. This opens unlimited possibilities concerning the level of complexity which can be reached, being only limited by the programming skills and the originality of the user.

  2. UPDATED USER-FRIENDLY COMPUTER PROGRAMS FOR SOLVING SAMPLING AND STATISTICAL PROBLEMS (FOR MICROCOMPUTERS) (DATE OF COVERAGE: 1993). - SOFTWARE.

    Science.gov (United States)

    The product contains user-friendly computer programs for solving sampling and related statistical problems. All have been updated as well and more programs have been added. Specific, detailed written instructions and examples built into the programs are provided so that the user ...

  3. An integrated user-friendly ArcMAP tool for bivariate statistical modeling in geoscience applications

    Science.gov (United States)

    Jebur, M. N.; Pradhan, B.; Shafri, H. Z. M.; Yusof, Z.; Tehrany, M. S.

    2014-10-01

    Modeling and classification difficulties are fundamental issues in natural hazard assessment. A geographic information system (GIS) is a domain that requires users to use various tools to perform different types of spatial modeling. Bivariate statistical analysis (BSA) assists in hazard modeling. To perform this analysis, several calculations are required and the user has to transfer data from one format to another. Most researchers perform these calculations manually by using Microsoft Excel or other programs. This process is time consuming and carries a degree of uncertainty. The lack of proper tools to implement BSA in a GIS environment prompted this study. In this paper, a user-friendly tool, BSM (bivariate statistical modeler), for BSA technique is proposed. Three popular BSA techniques such as frequency ratio, weights-of-evidence, and evidential belief function models are applied in the newly proposed ArcMAP tool. This tool is programmed in Python and is created by a simple graphical user interface, which facilitates the improvement of model performance. The proposed tool implements BSA automatically, thus allowing numerous variables to be examined. To validate the capability and accuracy of this program, a pilot test area in Malaysia is selected and all three models are tested by using the proposed program. Area under curve is used to measure the success rate and prediction rate. Results demonstrate that the proposed program executes BSA with reasonable accuracy. The proposed BSA tool can be used in numerous applications, such as natural hazard, mineral potential, hydrological, and other engineering and environmental applications.

  4. Modular modeling system for building distributed hydrologic models with a user-friendly software package

    Science.gov (United States)

    Wi, S.; Ray, P. A.; Brown, C.

    2015-12-01

    A software package developed to facilitate building distributed hydrologic models in a modular modeling system is presented. The software package provides a user-friendly graphical user interface that eases its practical use in water resources-related research and practice. The modular modeling system organizes the options available to users when assembling models according to the stages of hydrological cycle, such as potential evapotranspiration, soil moisture accounting, and snow/glacier melting processes. The software is intended to be a comprehensive tool that simplifies the task of developing, calibrating, validating, and using hydrologic models through the inclusion of intelligent automation to minimize user effort, and reduce opportunities for error. Processes so far automated include the definition of system boundaries (i.e., watershed delineation), climate and geographical input generation, and parameter calibration. Built-in post-processing toolkits greatly improve the functionality of the software as a decision support tool for water resources system management and planning. Example post-processing toolkits enable streamflow simulation at ungauged sites with predefined model parameters, and perform climate change risk assessment by means of the decision scaling approach. The software is validated through application to watersheds representing a variety of hydrologic regimes.

  5. Data publication, documentation and user friendly landing pages - improving data discovery and reuse

    Science.gov (United States)

    Elger, Kirsten; Ulbricht, Damian; Bertelmann, Roland

    2016-04-01

    Research data are the basis for scientific research and often irreplaceable (e.g. observational data). Storage of such data in appropriate, theme specific or institutional repositories is an essential part of ensuring their long term preservation and access. The free and open access to research data for reuse and scrutiny has been identified as a key issue by the scientific community as well as by research agencies and the public. To ensure the datasets to intelligible and usable for others they must be accompanied by comprehensive data description and standardized metadata for data discovery, and ideally should be published using digital object identifier (DOI). These make datasets citable and ensure their long-term accessibility and are accepted in reference lists of journal articles (http://www.copdess.org/statement-of-commitment/). The GFZ German Research Centre for Geosciences is the national laboratory for Geosciences in Germany and part of the Helmholtz Association, Germany's largest scientific organization. The development and maintenance of data systems is a key component of 'GFZ Data Services' to support state-of-the-art research. The datasets, archived in and published by the GFZ Data Repository cover all geoscientific disciplines and range from large dynamic datasets deriving from global monitoring seismic or geodetic networks with real-time data acquisition, to remotely sensed satellite products, to automatically generated data publications from a database for data from micro meteorological stations, to various model results, to geochemical and rock mechanical analyses from various labs, and field observations. The user-friendly presentation of published datasets via a DOI landing page is as important for reuse as the storage itself, and the required information is highly specific for each scientific discipline. If dataset descriptions are too general, or require the download of a dataset before knowing its suitability, many researchers often decide

  6. Measuring fish and their physical habitats: Versatile 2D and 3D video techniques with user-friendly software

    Science.gov (United States)

    Neuswanger, Jason R.; Wipfli, Mark S.; Rosenberger, Amanda E.; Hughes, Nicholas F.

    2017-01-01

    Applications of video in fisheries research range from simple biodiversity surveys to three-dimensional (3D) measurement of complex swimming, schooling, feeding, and territorial behaviors. However, researchers lack a transparently developed, easy-to-use, general purpose tool for 3D video measurement and event logging. Thus, we developed a new measurement system, with freely available, user-friendly software, easily obtained hardware, and flexible underlying mathematical methods capable of high precision and accuracy. The software, VidSync, allows users to efficiently record, organize, and navigate complex 2D or 3D measurements of fish and their physical habitats. Laboratory tests showed submillimetre accuracy in length measurements of 50.8 mm targets at close range, with increasing errors (mostly <1%) at longer range and for longer targets. A field test on juvenile Chinook salmon (Oncorhynchus tshawytscha) feeding behavior in Alaska streams found that individuals within aggregations avoided the immediate proximity of their competitors, out to a distance of 1.0 to 2.9 body lengths. This system makes 3D video measurement a practical tool for laboratory and field studies of aquatic or terrestrial animal behavior and ecology.

  7. Bioprocess Control in Microscale: Scalable Fermentations in Disposable and User-Friendly Microfluidic Systems

    Directory of Open Access Journals (Sweden)

    Müller Carsten

    2010-11-01

    Full Text Available Abstract Background The efficiency of biotechnological production processes depends on selecting the best performing microbial strain and the optimal cultivation conditions. Thus, many experiments have to be conducted, which conflicts with the demand to speed up drug development processes. Consequently, there is a great need for high-throughput devices that allow rapid and reliable bioprocess development. This need is addressed, for example, by the fiber-optic online-monitoring system BioLector which utilizes the wells of shaken microtiter plates (MTPs as small-scale fermenters. To further improve the application of MTPs as microbioreactors, in this paper, the BioLector technology is combined with microfluidic bioprocess control in MTPs. To realize a user-friendly system for routine laboratory work, disposable microfluidic MTPs are utilized which are actuated by a user-friendly pneumatic hardware. Results This novel microfermentation system was tested in pH-controlled batch as well as in fed-batch fermentations of Escherichia coli. The pH-value in the culture broth could be kept in a narrow dead band of 0.03 around the pH-setpoint, by pneumatically dosing ammonia solution and phosphoric acid to each culture well. Furthermore, fed-batch cultivations with linear and exponential feeding of 500 g/L glucose solution were conducted. Finally, the scale-up potential of the microscale fermentations was evaluated by comparing the obtained results to that of fully controlled fermentations in a 2 L laboratory-scale fermenter (working volume of 1 L. The scale-up was realized by keeping the volumetric mass transfer coefficient kLa constant at a value of 460 1/h. The same growth behavior of the E. coli cultures could be observed on both scales. Conclusion In microfluidic MTPs, pH-controlled batch as well as fed-batch fermentations were successfully performed. The liquid dosing as well as the biomass growth kinetics of the process-controlled fermentations

  8. miRSeq: A User-Friendly Standalone Toolkit for Sequencing Quality Evaluation and miRNA Profiling

    Directory of Open Access Journals (Sweden)

    Cheng-Tsung Pan

    2014-01-01

    Full Text Available MicroRNAs (miRNAs present diverse regulatory functions in a wide range of biological activities. Studies on miRNA functions generally depend on determining miRNA expression profiles between libraries by using a next-generation sequencing (NGS platform. Currently, several online web services are developed to provide small RNA NGS data analysis. However, the submission of large amounts of NGS data, conversion of data format, and limited availability of species bring problems. In this study, we developed miRSeq to provide alternatives. To test the performance, we had small RNA NGS data from four species, including human, rat, fly, and nematode, analyzed with miRSeq. The alignments results indicate that miRSeq can precisely evaluate the sequencing quality of samples regarding percentage of self-ligation read, read length distribution, and read category. miRSeq is a user-friendly standalone toolkit featuring a graphical user interface (GUI. After a simple installation, users can easily operate miRSeq on a PC or laptop by using a mouse. Within minutes, miRSeq yields useful miRNA data, including miRNA expression profiles, 3′ end modification patterns, and isomiR forms. Moreover, miRSeq supports the analysis of up to 105 animal species, providing higher flexibility.

  9. MicroSyn: A user friendly tool for detection of microsynteny in a gene family

    Directory of Open Access Journals (Sweden)

    Yang Xiaohan

    2011-03-01

    Full Text Available Abstract Background The traditional phylogeny analysis within gene family is mainly based on DNA or amino acid sequence homologies. However, these phylogenetic tree analyses are not suitable for those "non-traditional" gene families like microRNA with very short sequences. For the normal protein-coding gene families, low bootstrap values are frequently encountered in some nodes, suggesting low confidence or likely inappropriateness of placement of those members in those nodes. Results We introduce MicroSyn software as a means of detecting microsynteny in adjacent genomic regions surrounding genes in gene families. MicroSyn searches for conserved, flanking colinear homologous gene pairs between two genomic fragments to determine the relationship between two members in a gene family. The colinearity of homologous pairs is controlled by a statistical distance function. As a result, gene duplication history can be inferred from the output independent of gene sequences. MicroSyn was designed for both experienced and non-expert users with a user-friendly graphical-user interface. MicroSyn is available from: http://fcsb.njau.edu.cn/microsyn/. Conclusions Case studies of the microRNA167 genes in plants and Xyloglucan ndotransglycosylase/Hydrolase family in Populus trichocarpa were presented to show the utility of the software. The easy using of MicroSyn in these examples suggests that the software is an additional valuable means to address the problem intrinsic in the computational methods and sequence qualities themselves in gene family analysis.

  10. The HADDOCK2.2 Web Server: User-Friendly Integrative Modeling of Biomolecular Complexes.

    Science.gov (United States)

    van Zundert, G C P; Rodrigues, J P G L M; Trellet, M; Schmitz, C; Kastritis, P L; Karaca, E; Melquiond, A S J; van Dijk, M; de Vries, S J; Bonvin, A M J J

    2016-02-22

    The prediction of the quaternary structure of biomolecular macromolecules is of paramount importance for fundamental understanding of cellular processes and drug design. In the era of integrative structural biology, one way of increasing the accuracy of modeling methods used to predict the structure of biomolecular complexes is to include as much experimental or predictive information as possible in the process. This has been at the core of our information-driven docking approach HADDOCK. We present here the updated version 2.2 of the HADDOCK portal, which offers new features such as support for mixed molecule types, additional experimental restraints and improved protocols, all of this in a user-friendly interface. With well over 6000 registered users and 108,000 jobs served, an increasing fraction of which on grid resources, we hope that this timely upgrade will help the community to solve important biological questions and further advance the field. The HADDOCK2.2 Web server is freely accessible to non-profit users at http://haddock.science.uu.nl/services/HADDOCK2.2.

  11. Quantitative lateral flow strip assays as User-Friendly Tools To Detect Biomarker Profiles For Leprosy

    Science.gov (United States)

    van Hooij, Anouk; Tjon Kon Fat, Elisa M.; Richardus, Renate; van den Eeden, Susan J. F.; Wilson, Louis; de Dood, Claudia J.; Faber, Roel; Alam, Korshed; Richardus, Jan Hendrik; Corstjens, Paul L. A. M.; Geluk, Annemieke

    2016-01-01

    Leprosy is a debilitating, infectious disease caused by Mycobacterium leprae. Despite the availability of multidrug therapy, transmission is unremitting. Thus, early identification of M. leprae infection is essential to reduce transmission. The immune response to M. leprae is determined by host genetics, resulting in paucibacillary (PB) and multibacillary (MB) leprosy associated with dominant cellular or humoral immunity, respectively. This spectral pathology of leprosy compels detection of immunity to M. leprae to be based on multiple, diverse biomarkers. In this study we have applied quantitative user friendly lateral flow assays (LFAs) for four immune markers (anti-PGL-I antibodies, IL-10, CCL4 and IP-10) for whole blood samples from a longitudinal BCG vaccination field-trial in Bangladesh. Different biomarker profiles, in contrast to single markers, distinguished M. leprae infected from non-infected test groups, patients from household contacts (HHC) and endemic controls (EC), or MB from PB patients. The test protocol presented in this study merging detection of innate, adaptive cellular as well as humoral immunity, thus provides a convenient tool to measure specific biomarker profiles for M. leprae infection and leprosy utilizing a field-friendly technology. PMID:27682181

  12. Development of HydroImage, A User Friendly Hydrogeophysical Characterization Software

    Energy Technology Data Exchange (ETDEWEB)

    Mok, Chin Man [GSI Environmental; Hubbard, Susan [Lawrence Berkeley National Laboratory; Chen, Jinsong [Lawrence Berkeley National Laboratory; Suribhatla, Raghu [AMEC E& I; Kaback, Dawn Samara [AMEC E& I

    2014-01-29

    HydroImage, user friendly software that utilizes high-resolution geophysical data for estimating hydrogeological parameters in subsurface strate, was developed under this grant. HydroImage runs on a personal computer platform to promote broad use by hydrogeologists to further understanding of subsurface processes that govern contaminant fate, transport, and remediation. The unique software provides estimates of hydrogeological properties over continuous volumes of the subsurface, whereas previous approaches only allow estimation of point locations. thus, this unique tool can be used to significantly enhance site conceptual models and improve design and operation of remediation systems. The HydroImage technical approach uses statistical models to integrate geophysical data with borehole geological data and hydrological measurements to produce hydrogeological parameter estimates as 2-D or 3-D images.

  13. Towards a user-friendly brain-computer interface: initial tests in ALS and PLS patients.

    Science.gov (United States)

    Bai, Ou; Lin, Peter; Huang, Dandan; Fei, Ding-Yu; Floeter, Mary Kay

    2010-08-01

    Patients usually require long-term training for effective EEG-based brain-computer interface (BCI) control due to fatigue caused by the demands for focused attention during prolonged BCI operation. We intended to develop a user-friendly BCI requiring minimal training and less mental load. Testing of BCI performance was investigated in three patients with amyotrophic lateral sclerosis (ALS) and three patients with primary lateral sclerosis (PLS), who had no previous BCI experience. All patients performed binary control of cursor movement. One ALS patient and one PLS patient performed four-directional cursor control in a two-dimensional domain under a BCI paradigm associated with human natural motor behavior using motor execution and motor imagery. Subjects practiced for 5-10min and then participated in a multi-session study of either binary control or four-directional control including online BCI game over 1.5-2h in a single visit. Event-related desynchronization and event-related synchronization in the beta band were observed in all patients during the production of voluntary movement either by motor execution or motor imagery. The online binary control of cursor movement was achieved with an average accuracy about 82.1+/-8.2% with motor execution and about 80% with motor imagery, whereas offline accuracy was achieved with 91.4+/-3.4% with motor execution and 83.3+/-8.9% with motor imagery after optimization. In addition, four-directional cursor control was achieved with an accuracy of 50-60% with motor execution and motor imagery. Patients with ALS or PLS may achieve BCI control without extended training, and fatigue might be reduced during operation of a BCI associated with human natural motor behavior. The development of a user-friendly BCI will promote practical BCI applications in paralyzed patients. Copyright 2010 International Federation of Clinical Neurophysiology. All rights reserved.

  14. An integrated user-friendly ArcMAP tool for bivariate statistical modelling in geoscience applications

    Science.gov (United States)

    Jebur, M. N.; Pradhan, B.; Shafri, H. Z. M.; Yusoff, Z. M.; Tehrany, M. S.

    2015-03-01

    Modelling and classification difficulties are fundamental issues in natural hazard assessment. A geographic information system (GIS) is a domain that requires users to use various tools to perform different types of spatial modelling. Bivariate statistical analysis (BSA) assists in hazard modelling. To perform this analysis, several calculations are required and the user has to transfer data from one format to another. Most researchers perform these calculations manually by using Microsoft Excel or other programs. This process is time-consuming and carries a degree of uncertainty. The lack of proper tools to implement BSA in a GIS environment prompted this study. In this paper, a user-friendly tool, bivariate statistical modeler (BSM), for BSA technique is proposed. Three popular BSA techniques, such as frequency ratio, weight-of-evidence (WoE), and evidential belief function (EBF) models, are applied in the newly proposed ArcMAP tool. This tool is programmed in Python and created by a simple graphical user interface (GUI), which facilitates the improvement of model performance. The proposed tool implements BSA automatically, thus allowing numerous variables to be examined. To validate the capability and accuracy of this program, a pilot test area in Malaysia is selected and all three models are tested by using the proposed program. Area under curve (AUC) is used to measure the success rate and prediction rate. Results demonstrate that the proposed program executes BSA with reasonable accuracy. The proposed BSA tool can be used in numerous applications, such as natural hazard, mineral potential, hydrological, and other engineering and environmental applications.

  15. GUARDD: user-friendly MATLAB software for rigorous analysis of CPMG RD NMR data.

    Science.gov (United States)

    Kleckner, Ian R; Foster, Mark P

    2012-01-01

    Molecular dynamics are essential for life, and nuclear magnetic resonance (NMR) spectroscopy has been used extensively to characterize these phenomena since the 1950s. For the past 15 years, the Carr-Purcell Meiboom-Gill relaxation dispersion (CPMG RD) NMR experiment has afforded advanced NMR labs access to kinetic, thermodynamic, and structural details of protein and RNA dynamics in the crucial μs-ms time window. However, analysis of RD data is challenging because datasets are often large and require many non-linear fitting parameters, thereby confounding assessment of accuracy. Moreover, novice CPMG experimentalists face an additional barrier because current software options lack an intuitive user interface and extensive documentation. Hence, we present the open-source software package GUARDD (Graphical User-friendly Analysis of Relaxation Dispersion Data), which is designed to organize, automate, and enhance the analytical procedures which operate on CPMG RD data ( http://code.google.com/p/guardd/). This MATLAB-based program includes a graphical user interface, permits global fitting to multi-field, multi-temperature, multi-coherence data, and implements χ (2)-mapping procedures, via grid-search and Monte Carlo methods, to enhance and assess fitting accuracy. The presentation features allow users to seamlessly traverse the large amount of results, and the RD Simulator feature can help design future experiments as well as serve as a teaching tool for those unfamiliar with RD phenomena. Based on these innovative features, we expect that GUARDD will fill a well-defined gap in service of the RD NMR community.

  16. An integrated user-friendly ArcMAP tool for bivariate statistical modeling in geoscience applications

    Directory of Open Access Journals (Sweden)

    M. N. Jebur

    2014-10-01

    Full Text Available Modeling and classification difficulties are fundamental issues in natural hazard assessment. A geographic information system (GIS is a domain that requires users to use various tools to perform different types of spatial modeling. Bivariate statistical analysis (BSA assists in hazard modeling. To perform this analysis, several calculations are required and the user has to transfer data from one format to another. Most researchers perform these calculations manually by using Microsoft Excel or other programs. This process is time consuming and carries a degree of uncertainty. The lack of proper tools to implement BSA in a GIS environment prompted this study. In this paper, a user-friendly tool, BSM (bivariate statistical modeler, for BSA technique is proposed. Three popular BSA techniques such as frequency ratio, weights-of-evidence, and evidential belief function models are applied in the newly proposed ArcMAP tool. This tool is programmed in Python and is created by a simple graphical user interface, which facilitates the improvement of model performance. The proposed tool implements BSA automatically, thus allowing numerous variables to be examined. To validate the capability and accuracy of this program, a pilot test area in Malaysia is selected and all three models are tested by using the proposed program. Area under curve is used to measure the success rate and prediction rate. Results demonstrate that the proposed program executes BSA with reasonable accuracy. The proposed BSA tool can be used in numerous applications, such as natural hazard, mineral potential, hydrological, and other engineering and environmental applications.

  17. Does this range suit me? Range satisfaction of battery electric vehicle users.

    Science.gov (United States)

    Franke, Thomas; Günther, Madlen; Trantow, Maria; Krems, Josef F

    2017-11-01

    User satisfaction is a vital design criterion for sustainable systems. The present research aimed to understand factors relating to individually perceived range satisfaction of battery electric vehicle (BEV) users. Data from a large-scale BEV field trial (N = 72) were analyzed. Apart from an initial drop in range satisfaction, increasing practical experience was related to increased range satisfaction. Classical indicators of users' mobility profiles (daily travel distances) were only weakly related to lower range satisfaction (not significant), after controlling for practical experience and preferred coverage of mobility needs. The regularity/predictability of users' mobility patterns, the percentage of journeys not coverable because of range issues, and users' individual comfortable range accounted for variance in range satisfaction. Finally, range satisfaction was related to key indicators of general BEV acceptance (e.g., purchase intentions). These results underline the complex dynamics involved in individual range satisfaction, as well as its central role for BEV acceptance. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. A user-friendly software to easily count Anopheles egg batches

    Directory of Open Access Journals (Sweden)

    Mollahosseini Ali

    2012-06-01

    Full Text Available Abstract Background Studies on malaria vector ecology and development/evaluation of vector control strategies often require measures of mosquito life history traits. Assessing the fecundity of malaria vectors can be carried out by counting eggs laid by Anopheles females. However, manually counting the eggs is time consuming, tedious, and error prone. Methods In this paper we present a newly developed software for high precision automatic egg counting. The software written in the Java programming language proposes a user-friendly interface and a complete online manual. It allows the inspection of results by the operator and includes proper tools for manual corrections. The user can in fact correct any details on the acquired results by a mouse click. Time saving is significant and errors due to loss of concentration are avoided. Results The software was tested over 16 randomly chosen images from 2 different experiments. The results show that the proposed automatic method produces results that are close to the ground truth. Conclusions The proposed approaches demonstrated a very high level of robustness. The adoption of the proposed software package will save many hours of labor to the bench scientist. The software needs no particular configuration and is freely available for download on: http://w3.ualg.pt/∼hshah/eggcounter/.

  19. Nestedness for Dummies (NeD: A User-Friendly Web Interface for Exploratory Nestedness Analysis

    Directory of Open Access Journals (Sweden)

    Giovanni Strona

    2014-08-01

    Full Text Available Recent theoretical advances in nestedness analysis have led to the introduction of several alternative metrics to overcome most of the problems biasing the use of matrix 'temperature' calculated by Atmar's Nestedness Temperature Calculator. However, all of the currently available programs for nestedness analysis lack the user friendly appeal that has made the Nestedness Temperature Calculator one of the most popular community ecology programs. The software package NeD is an intuitive open source application for nestedness analysis that can be used online or locally under different operating systems. NeD is able to automatically handle different matrix formats, has batch functionalities and produces an output that can be easily copied and pasted to a spreadsheet. In addition to numerical results, NeD provides a graphic representation of the matrix under examination and of the corresponding maximally packed matrix. NeD allows users to select among the most used nestedness metrics, and to combine them with different null models. Integrating easiness of use with the recent theoretical advances in the field, NeD provides researchers not directly involved in theoretical debates with a simple yet robust statistical tool for a more conscious performance of nestedness analysis. NeD can be accessed at http: //purl.oclc.org/ned.

  20. PuffinPlot: A versatile, user-friendly program for paleomagnetic analysis

    Science.gov (United States)

    Lurcock, P. C.; Wilson, G. S.

    2012-06-01

    PuffinPlot is a user-friendly desktop application for analysis of paleomagnetic data, offering a unique combination of features. It runs on several operating systems, including Windows, Mac OS X, and Linux; supports both discrete and long core data; and facilitates analysis of very weakly magnetic samples. As well as interactive graphical operation, PuffinPlot offers batch analysis for large volumes of data, and a Python scripting interface for programmatic control of its features. Available data displays include demagnetization/intensity, Zijderveld, equal-area (for sample, site, and suite level demagnetization data, and for magnetic susceptibility anisotropy data), a demagnetization data table, and a natural remanent magnetization intensity histogram. Analysis types include principal component analysis, Fisherian statistics, and great-circle path intersections. The results of calculations can be exported as CSV (comma-separated value) files; graphs can be printed, and can also be saved as publication-quality vector files in SVG or PDF format. PuffinPlot is free, and the program, user manual, and fully documented source code may be downloaded from http://code.google.com/p/puffinplot/.

  1. A user-friendly nano-CT image alignment and 3D reconstruction platform based on LabVIEW

    Science.gov (United States)

    Wang, Sheng-Hao; Zhang, Kai; Wang, Zhi-Li; Gao, Kun; Wu, Zhao; Zhu, Pei-Ping; Wu, Zi-Yu

    2015-01-01

    X-ray computed tomography at the nanometer scale (nano-CT) offers a wide range of applications in scientific and industrial areas. Here we describe a reliable, user-friendly, and fast software package based on LabVIEW that may allow us to perform all procedures after the acquisition of raw projection images in order to obtain the inner structure of the investigated sample. A suitable image alignment process to address misalignment problems among image series due to mechanical manufacturing errors, thermal expansion, and other external factors has been considered, together with a novel fast parallel beam 3D reconstruction procedure that was developed ad hoc to perform the tomographic reconstruction. We have obtained remarkably improved reconstruction results at the Beijing Synchrotron Radiation Facility after the image calibration, the fundamental role of this image alignment procedure was confirmed, which minimizes the unwanted blurs and additional streaking artifacts that are always present in reconstructed slices. Moreover, this nano-CT image alignment and its associated 3D reconstruction procedure are fully based on LabVIEW routines, significantly reducing the data post-processing cycle, thus making the activity of the users faster and easier during experimental runs.

  2. A user-friendly, low-cost turbidostat with versatile growth rate estimation based on an extended Kalman filter.

    Science.gov (United States)

    Hoffmann, Stefan A; Wohltat, Christian; Müller, Kristian M; Arndt, Katja M

    2017-01-01

    For various experimental applications, microbial cultures at defined, constant densities are highly advantageous over simple batch cultures. Due to high costs, however, devices for continuous culture at freely defined densities still experience limited use. We have developed a small-scale turbidostat for research purposes, which is manufactured from inexpensive components and 3D printed parts. A high degree of spatial system integration and a graphical user interface provide user-friendly operability. The used optical density feedback control allows for constant continuous culture at a wide range of densities and offers to vary culture volume and dilution rates without additional parametrization. Further, a recursive algorithm for on-line growth rate estimation has been implemented. The employed Kalman filtering approach based on a very general state model retains the flexibility of the used control type and can be easily adapted to other bioreactor designs. Within several minutes it can converge to robust, accurate growth rate estimates. This is particularly useful for directed evolution experiments or studies on metabolic challenges, as it allows direct monitoring of the population fitness.

  3. Construction and validation of a patient- and user-friendly nursing home version of the Geriatric Depression Scale

    NARCIS (Netherlands)

    Jongenelis, K.; Gerritsen, D. L.; Beekman, A. T. F.; Eisses, A. M. H.; Kluiter, H.; Ribbe, M. W.

    Objective To construct a patient- and user-friendly shortened version of the Geriatric Depression Scale (GDS) that is especially suitable for nursing home patients. Methods The study was carried out on two different data bases including 23 Dutch nursing homes. Data on the GDS (n = 410), the Mini

  4. Construction and validation of a patient- and user-friendly nursing home version of the Geriatric Depression Scale

    NARCIS (Netherlands)

    Jongenelis, K.; Gerritsen, D. L.; Beekman, A. T. F.; Eisses, A. M. H.; Kluiter, H.; Ribbe, M. W.

    2007-01-01

    Objective To construct a patient- and user-friendly shortened version of the Geriatric Depression Scale (GDS) that is especially suitable for nursing home patients. Methods The study was carried out on two different data bases including 23 Dutch nursing homes. Data on the GDS (n = 410), the Mini Men

  5. TIME Impact - a new user-friendly tuberculosis (TB) model to inform TB policy decisions.

    Science.gov (United States)

    Houben, R M G J; Lalli, M; Sumner, T; Hamilton, M; Pedrazzoli, D; Bonsu, F; Hippner, P; Pillay, Y; Kimerling, M; Ahmedov, S; Pretorius, C; White, R G

    2016-03-24

    Tuberculosis (TB) is the leading cause of death from infectious disease worldwide, predominantly affecting low- and middle-income countries (LMICs), where resources are limited. As such, countries need to be able to choose the most efficient interventions for their respective setting. Mathematical models can be valuable tools to inform rational policy decisions and improve resource allocation, but are often unavailable or inaccessible for LMICs, particularly in TB. We developed TIME Impact, a user-friendly TB model that enables local capacity building and strengthens country-specific policy discussions to inform support funding applications at the (sub-)national level (e.g. Ministry of Finance) or to international donors (e.g. the Global Fund to Fight AIDS, Tuberculosis and Malaria).TIME Impact is an epidemiological transmission model nested in TIME, a set of TB modelling tools available for free download within the widely-used Spectrum software. The TIME Impact model reflects key aspects of the natural history of TB, with additional structure for HIV/ART, drug resistance, treatment history and age. TIME Impact enables national TB programmes (NTPs) and other TB policymakers to better understand their own TB epidemic, plan their response, apply for funding and evaluate the implementation of the response.The explicit aim of TIME Impact's user-friendly interface is to enable training of local and international TB experts towards independent use. During application of TIME Impact, close involvement of the NTPs and other local partners also builds critical understanding of the modelling methods, assumptions and limitations inherent to modelling. This is essential to generate broad country-level ownership of the modelling data inputs and results. In turn, it stimulates discussions and a review of the current evidence and assumptions, strengthening the decision-making process in general.TIME Impact has been effectively applied in a variety of settings. In South Africa, it

  6. A New Way to Lemmatize Adjectives in a User-friendly Zulu–English Dictionary

    Directory of Open Access Journals (Sweden)

    Gilles-Maurice de Schryver

    2011-10-01

    Full Text Available

    Abstract: Traditionally, Zulu adjectives have been lemmatized under their stems only. In this research article, an in-depth analysis is undertaken to make a case for the lemmatization of all frequent adjectival forms with their adjective concords rather. It is shown that the supposed explosion in size of the dictionary may be contained within a corpus-driven Sinclairian framework. The advantages of such a word-like treatment far outnumber the generalizations that have hitherto characterized the lexicographic treatment of adjectives in Zulu. The study is supported by ample dictionary extracts from a Zulu–English dictionary project aimed at junior users. Comparisons with existing dictionaries and textbook data are also made.

    Keywords: LEXICOGRAPHY, LINGUISTICS, GRAMMAR, DICTIONARY, BILINGUAL,CORPUS, LEMMATIZATION, FREQUENCY, ZULU (ISIZULU, ENGLISH, ADJECTIVE,ADJECTIVE STEM, QUALIFICATIVE ADJECTIVE, COPULATIVE ADJECTIVE, USER-FRIENDLY,REAL EXAMPLE, COLLOCATION, COMBINATION, DERIVATION, IDIOMATIC USE,SEMANTIC PROSODY

    Samenvatting: Een nieuwe manier om adjectieven te lemmatiseren in eengebruiksvriendelijk Zoeloe–Engels woordenboek. Traditioneel worden adjectievenin Zoeloe enkel onder hun stam gelemmatiseerd. In dit onderzoeksartikel wordt een grondigeanalyse uitgevoerd met het oog op de invoering van een nieuwe methode waarbij alle frequenteadjectieven met hun adjectiefschakel in het woordenboek worden geplaatst. Er wordt aangetoond datde vooronderstelde explosie in grootte van het woordenboek beperkt kan worden binnen een corpusgedrevenSinclairiaans kader. De voordelen van zo een woordachtige behandeling overstijgenruimschoots de veralgemeningen die totnogtoe de lexicografische behandeling van adjectieven inZoeloe hebben gekarakteriseerd. De studie wordt ondersteund door een groot aantal passages uiteen Zoeloe–Engels woordenboekproject gericht op jonge gebruikers. Vergelijkingen met bestaandewoordenboeken, alsook handboeken

  7. Mapping mutations in plant genomes with the user-friendly web application CandiSNP.

    Science.gov (United States)

    Etherington, Graham J; Monaghan, Jacqueline; Zipfel, Cyril; MacLean, Dan

    2014-01-01

    Analysis of mutants isolated from forward-genetic screens has revealed key components of several plant signalling pathways. Mapping mutations by position, either using classical methods or whole genome high-throughput sequencing (HTS), largely relies on the analysis of genome-wide polymorphisms in F2 recombinant populations. Combining bulk segregant analysis with HTS has accelerated the identification of causative mutations and has been widely adopted in many research programmes. A major advantage of HTS is the ability to perform bulk segregant analysis after back-crossing to the parental line rather than out-crossing to a polymorphic ecotype, which reduces genetic complexity and avoids issues with phenotype penetrance in different ecotypes. Plotting the positions of homozygous polymorphisms in a mutant genome identifies areas of low recombination and is an effective way to detect molecular linkage to a phenotype of interest. We describe the use of single nucleotide polymorphism (SNP) density plots as a mapping strategy to identify and refine chromosomal positions of causative mutations from screened plant populations. We developed a web application called CandiSNP that generates density plots from user-provided SNP data obtained from HTS. Candidate causative mutations, defined as SNPs causing non-synonymous changes in annotated coding regions are highlighted on the plots and listed in a table. We use data generated from a recent mutant screen in the model plant Arabidopsis thaliana as proof-of-concept for the validity of our tool. CandiSNP is a user-friendly application that will aid in novel discoveries from forward-genetic mutant screens. It is particularly useful for analysing HTS data from bulked back-crossed mutants, which contain fewer polymorphisms than data generated from out-crosses. The web-application is freely available online at http://candisnp.tsl.ac.uk.

  8. u-CARE: user-friendly Comprehensive Antibiotic resistance Repository of Escherichia coli.

    Science.gov (United States)

    Saha, Saurav B; Uttam, Vishwas; Verma, Vivek

    2015-08-01

    Despite medical advancements, Escherichia coli-associated infections remain a major public health concern and although an abundant information about E. coli and its antibiotic resistance mechanisms is available, no effective tool exists that integrates gene and genomic data in context to drug resistance, thus raising a need to develop a repository that facilitates integration and assimilation of factors governing drug resistance in E. coli. User-friendly Comprehensive Antibiotic resistance Repository of Escherichia coli (u-CARE) is a manually curated catalogue of 52 antibiotics with reported resistance, 107 genes, transcription factors and single nucleotide polymorphism (SNPs) involved in multiple drug resistance of this pathogen. Each gene page provides detailed information about its resistance mechanisms, while antibiotic page consists of summary, chemical description and structural descriptors with links to external public databases like GO, CDD, DEG, Ecocyc, KEGG, Drug Bank, PubChem and UniProt. Moreover, the database integrates this reductive information to holistic data such as strain-specific and segment-specific pathogenic islands and operons. In addition, the database offers rich user interface for the visualisation and retrieval of information using various search criteria such as sequence, keyword, image and class search. u-CARE is aimed to cater to the needs of researchers working in the field of antimicrobial drug resistance with minimal knowledge of bioinformatics. This database is also intended as a guide book to medical practitioners to avoid use of antibiotics against which resistance has already been reported in E. coli. The database is available from: http://www.e-bioinformatics.net/ucare. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  9. BUMPER v1.0: a Bayesian user-friendly model for palaeo-environmental reconstruction

    Science.gov (United States)

    Holden, Philip B.; Birks, H. John B.; Brooks, Stephen J.; Bush, Mark B.; Hwang, Grace M.; Matthews-Bird, Frazer; Valencia, Bryan G.; van Woesik, Robert

    2017-02-01

    We describe the Bayesian user-friendly model for palaeo-environmental reconstruction (BUMPER), a Bayesian transfer function for inferring past climate and other environmental variables from microfossil assemblages. BUMPER is fully self-calibrating, straightforward to apply, and computationally fast, requiring ˜ 2 s to build a 100-taxon model from a 100-site training set on a standard personal computer. We apply the model's probabilistic framework to generate thousands of artificial training sets under ideal assumptions. We then use these to demonstrate the sensitivity of reconstructions to the characteristics of the training set, considering assemblage richness, taxon tolerances, and the number of training sites. We find that a useful guideline for the size of a training set is to provide, on average, at least 10 samples of each taxon. We demonstrate general applicability to real data, considering three different organism types (chironomids, diatoms, pollen) and different reconstructed variables. An identically configured model is used in each application, the only change being the input files that provide the training-set environment and taxon-count data. The performance of BUMPER is shown to be comparable with weighted average partial least squares (WAPLS) in each case. Additional artificial datasets are constructed with similar characteristics to the real data, and these are used to explore the reasons for the differing performances of the different training sets.

  10. BUMPER: the Bayesian User-friendly Model for Palaeo-Environmental Reconstruction

    Science.gov (United States)

    Holden, Phil; Birks, John; Brooks, Steve; Bush, Mark; Hwang, Grace; Matthews-Bird, Frazer; Valencia, Bryan; van Woesik, Robert

    2017-04-01

    We describe the Bayesian User-friendly Model for Palaeo-Environmental Reconstruction (BUMPER), a Bayesian transfer function for inferring past climate and other environmental variables from microfossil assemblages. The principal motivation for a Bayesian approach is that the palaeoenvironment is treated probabilistically, and can be updated as additional data become available. Bayesian approaches therefore provide a reconstruction-specific quantification of the uncertainty in the data and in the model parameters. BUMPER is fully self-calibrating, straightforward to apply, and computationally fast, requiring 2 seconds to build a 100-taxon model from a 100-site training-set on a standard personal computer. We apply the model's probabilistic framework to generate thousands of artificial training-sets under ideal assumptions. We then use these to demonstrate both the general applicability of the model and the sensitivity of reconstructions to the characteristics of the training-set, considering assemblage richness, taxon tolerances, and the number of training sites. We demonstrate general applicability to real data, considering three different organism types (chironomids, diatoms, pollen) and different reconstructed variables. In all of these applications an identically configured model is used, the only change being the input files that provide the training-set environment and taxon-count data.

  11. PAPST, a User Friendly and Powerful Java Platform for ChIP-Seq Peak Co-Localization Analysis and Beyond.

    Directory of Open Access Journals (Sweden)

    Paul W Bible

    Full Text Available Comparative co-localization analysis of transcription factors (TFs and epigenetic marks (EMs in specific biological contexts is one of the most critical areas of ChIP-Seq data analysis beyond peak calling. Yet there is a significant lack of user-friendly and powerful tools geared towards co-localization analysis based exploratory research. Most tools currently used for co-localization analysis are command line only and require extensive installation procedures and Linux expertise. Online tools partially address the usability issues of command line tools, but slow response times and few customization features make them unsuitable for rapid data-driven interactive exploratory research. We have developed PAPST: Peak Assignment and Profile Search Tool, a user-friendly yet powerful platform with a unique design, which integrates both gene-centric and peak-centric co-localization analysis into a single package. Most of PAPST's functions can be completed in less than five seconds, allowing quick cycles of data-driven hypothesis generation and testing. With PAPST, a researcher with or without computational expertise can perform sophisticated co-localization pattern analysis of multiple TFs and EMs, either against all known genes or a set of genomic regions obtained from public repositories or prior analysis. PAPST is a versatile, efficient, and customizable tool for genome-wide data-driven exploratory research. Creatively used, PAPST can be quickly applied to any genomic data analysis that involves a comparison of two or more sets of genomic coordinate intervals, making it a powerful tool for a wide range of exploratory genomic research. We first present PAPST's general purpose features then apply it to several public ChIP-Seq data sets to demonstrate its rapid execution and potential for cutting-edge research with a case study in enhancer analysis. To our knowledge, PAPST is the first software of its kind to provide efficient and sophisticated post

  12. PAPST, a User Friendly and Powerful Java Platform for ChIP-Seq Peak Co-Localization Analysis and Beyond.

    Science.gov (United States)

    Bible, Paul W; Kanno, Yuka; Wei, Lai; Brooks, Stephen R; O'Shea, John J; Morasso, Maria I; Loganantharaj, Rasiah; Sun, Hong-Wei

    2015-01-01

    Comparative co-localization analysis of transcription factors (TFs) and epigenetic marks (EMs) in specific biological contexts is one of the most critical areas of ChIP-Seq data analysis beyond peak calling. Yet there is a significant lack of user-friendly and powerful tools geared towards co-localization analysis based exploratory research. Most tools currently used for co-localization analysis are command line only and require extensive installation procedures and Linux expertise. Online tools partially address the usability issues of command line tools, but slow response times and few customization features make them unsuitable for rapid data-driven interactive exploratory research. We have developed PAPST: Peak Assignment and Profile Search Tool, a user-friendly yet powerful platform with a unique design, which integrates both gene-centric and peak-centric co-localization analysis into a single package. Most of PAPST's functions can be completed in less than five seconds, allowing quick cycles of data-driven hypothesis generation and testing. With PAPST, a researcher with or without computational expertise can perform sophisticated co-localization pattern analysis of multiple TFs and EMs, either against all known genes or a set of genomic regions obtained from public repositories or prior analysis. PAPST is a versatile, efficient, and customizable tool for genome-wide data-driven exploratory research. Creatively used, PAPST can be quickly applied to any genomic data analysis that involves a comparison of two or more sets of genomic coordinate intervals, making it a powerful tool for a wide range of exploratory genomic research. We first present PAPST's general purpose features then apply it to several public ChIP-Seq data sets to demonstrate its rapid execution and potential for cutting-edge research with a case study in enhancer analysis. To our knowledge, PAPST is the first software of its kind to provide efficient and sophisticated post peak-calling Ch

  13. BMPOS: a Flexible and User-Friendly Tool Sets for Microbiome Studies.

    Science.gov (United States)

    Pylro, Victor S; Morais, Daniel K; de Oliveira, Francislon S; Dos Santos, Fausto G; Lemos, Leandro N; Oliveira, Guilherme; Roesch, Luiz F W

    2016-08-01

    Recent advances in science and technology are leading to a revision and re-orientation of methodologies, addressing old and current issues under a new perspective. Advances in next generation sequencing (NGS) are allowing comparative analysis of the abundance and diversity of whole microbial communities, generating a large amount of data and findings at a systems level. The current limitation for biologists has been the increasing demand for computational power and training required for processing of NGS data. Here, we describe the deployment of the Brazilian Microbiome Project Operating System (BMPOS), a flexible and user-friendly Linux distribution dedicated to microbiome studies. The Brazilian Microbiome Project (BMP) has developed data analyses pipelines for metagenomic studies (phylogenetic marker genes), conducted using the two main high-throughput sequencing platforms (Ion Torrent and Illumina MiSeq). The BMPOS is freely available and possesses the entire requirement of bioinformatics packages and databases to perform all the pipelines suggested by the BMP team. The BMPOS may be used as a bootable live USB stick or installed in any computer with at least 1 GHz CPU and 512 MB RAM, independent of the operating system previously installed. The BMPOS has proved to be effective for sequences processing, sequences clustering, alignment, taxonomic annotation, statistical analysis, and plotting of metagenomic data. The BMPOS has been used during several metagenomic analyses courses, being valuable as a tool for training, and an excellent starting point to anyone interested in performing metagenomic studies. The BMPOS and its documentation are available at http://www.brmicrobiome.org .

  14. A Cost Effective and User Friendly Approach to Design Wireline Formation Tests

    Directory of Open Access Journals (Sweden)

    Clara Bertolini

    2009-01-01

    Full Text Available Problem statement: Wireline formation testing (also named Mini-DSTs are gaining more and more popularity as a possible alternative to conventional well testing especially where there are major environmental and economical constraints. The increased offshore exploration activity, which often implies highly risky and huge operational costs, makes the conventional well testing less attractive in favor of other technologies that can provide some of the key dynamic information about the well-reservoir system through relatively quick and less expensive operations. The design phase is recognized to be one of the most critical aspects in order to guarantee an acceptable value of information in exploration scenarios where very limited data is available. The success of any mini-DST operation can be significantly compromised if two major issues are not addressed in the design phase: possibility to clearly identify the radial flow behavior and avoidance of noise in the pressure response due to the gauge resolution. Approach: The study consisted in the development of a new tool for mini-DST design to easily identify whether this technology can be successfully applied. The tool comprises dimensionless and dimensional charts, which are of general validity because they can be applied to any lithological environment and for any type of hydrocarbon. Results: Field applications proved the reliability of the charts: First of all the test durations were optimized to collect interpretable bottomhole pressures and to obtain valid reservoir characterizations. Besides, a cost saving effectiveness was achieved avoiding the acquisition of useless extra-data affected by noise due to gauge resolution. Conclusion/Recommendations: The use of the charts is strongly suggested at the early stage of decision making for new exploration/appraisal operations; they are a user-friendly tool for assessing the feasibility of a mini-DST test. Additionally, the charts are more versatile

  15. SMARTIES: User-friendly codes for fast and accurate calculations of light scattering by spheroids

    Science.gov (United States)

    Somerville, W. R. C.; Auguié, B.; Le Ru, E. C.

    2016-05-01

    We provide a detailed user guide for SMARTIES, a suite of MATLAB codes for the calculation of the optical properties of oblate and prolate spheroidal particles, with comparable capabilities and ease-of-use as Mie theory for spheres. SMARTIES is a MATLAB implementation of an improved T-matrix algorithm for the theoretical modelling of electromagnetic scattering by particles of spheroidal shape. The theory behind the improvements in numerical accuracy and convergence is briefly summarized, with reference to the original publications. Instructions of use, and a detailed description of the code structure, its range of applicability, as well as guidelines for further developments by advanced users are discussed in separate sections of this user guide. The code may be useful to researchers seeking a fast, accurate and reliable tool to simulate the near-field and far-field optical properties of elongated particles, but will also appeal to other developers of light-scattering software seeking a reliable benchmark for non-spherical particles with a challenging aspect ratio and/or refractive index contrast.

  16. GProX, a User-Friendly Platform for Bioinformatics Analysis and Visualization of Quantitative Proteomics Data

    DEFF Research Database (Denmark)

    Rigbolt, Kristoffer T G; Vanselow, Jens T; Blagoev, Blagoy

    2011-01-01

    -friendly platform for comprehensive analysis, inspection and visualization of quantitative proteomics data we developed the Graphical Proteomics Data Explorer (GProX)(1). The program requires no special bioinformatics training, as all functions of GProX are accessible within its graphical user-friendly interface...... which will be intuitive to most users. Basic features facilitate the uncomplicated management and organization of large data sets and complex experimental setups as well as the inspection and graphical plotting of quantitative data. These are complemented by readily available high-level analysis options...... such as database querying, clustering based on abundance ratios, feature enrichment tests for e.g. GO terms and pathway analysis tools. A number of plotting options for visualization of quantitative proteomics data is available and most analysis functions in GProX create customizable high quality graphical...

  17. Flowing Hot or Cold: User-Friendly Computational Models of Terrestrial and Planetary Lava Channels and Lakes

    Science.gov (United States)

    Sakimoto, S. E. H.

    2016-12-01

    Planetary volcanism has redefined what is considered volcanism. "Magma" now may be considered to be anything from the molten rock familiar at terrestrial volcanoes to cryovolcanic ammonia-water mixes erupted on an outer solar system moon. However, even with unfamiliar compositions and source mechanisms, we find familiar landforms such as volcanic channels, lakes, flows, and domes and thus a multitude of possibilities for modeling. As on Earth, these landforms lend themselves to analysis for estimating storage, eruption and/or flow rates. This has potential pitfalls, as extension of the simplified analytic models we often use for terrestrial features into unfamiliar parameter space might yield misleading results. Our most commonly used tools for estimating flow and cooling have tended to lag significantly behind state-of-the-art; the easiest methods to use are neither realistic or accurate, but the more realistic and accurate computational methods are not simple to use. Since the latter computational tools tend to be both expensive and require a significant learning curve, there is a need for a user-friendly approach that still takes advantage of their accuracy. One method is use of the computational package for generation of a server-based tool that allows less computationally inclined users to get accurate results over their range of input parameters for a given problem geometry. A second method is to use the computational package for the generation of a polynomial empirical solution for each class of flow geometry that can be fairly easily solved by anyone with a spreadsheet. In this study, we demonstrate both approaches for several channel flow and lava lake geometries with terrestrial and extraterrestrial examples and compare their results. Specifically, we model cooling rectangular channel flow with a yield strength material, with applications to Mauna Loa, Kilauea, Venus, and Mars. This approach also shows promise with model applications to lava lakes, magma

  18. UCTM2: An updated User friendly Configurable Trigger, scaler and delay Module for nuclear and particle physics

    CERN Document Server

    Bourrion, O; Derome, L; Pignol, G

    2016-01-01

    We developed a highly integrated and versatile electronic module to equip small nuclear physics experiments and lab teaching classes: the User friendly Configurable Trigger, scaler and delay Module for nuclear and particle physics (UCTM). It is configurable through a Graphical User Interface (GUI) and provides a large number of possible trigger conditions without any Hardware Description Language (HDL) required knowledge. This new version significantly enhances the previous capabilities by providing two additional features: signal digitization and time measurements. The design, performances and a typical application are presented.

  19. UCTM2: An updated User friendly Configurable Trigger, scaler and delay Module for nuclear and particle physics

    Science.gov (United States)

    Bourrion, O.; Boyer, B.; Derome, L.; Pignol, G.

    2016-06-01

    We developed a highly integrated and versatile electronic module to equip small nuclear physics experiments and lab teaching classes: the User friendly Configurable Trigger, scaler and delay Module for nuclear and particle physics (UCTM). It is configurable through a Graphical User Interface (GUI) and provides a large number of possible trigger conditions without any Hardware Description Language (HDL) required knowledge. This new version significantly enhances the previous capabilities by providing two additional features: signal digitization and time measurements. The design, performances and a typical application are presented.

  20. UCTM2: An updated User friendly Configurable Trigger, scaler and delay Module for nuclear and particle physics

    Energy Technology Data Exchange (ETDEWEB)

    Bourrion, O., E-mail: olivier.bourrion@lpsc.in2p3.fr; Boyer, B.; Derome, L.; Pignol, G.

    2016-06-11

    We developed a highly integrated and versatile electronic module to equip small nuclear physics experiments and lab teaching classes: the User friendly Configurable Trigger, scaler and delay Module for nuclear and particle physics (UCTM). It is configurable through a Graphical User Interface (GUI) and provides a large number of possible trigger conditions without any Hardware Description Language (HDL) required knowledge. This new version significantly enhances the previous capabilities by providing two additional features: signal digitization and time measurements. The design, performances and a typical application are presented.

  1. 浅析婴儿车的人性化设计%ANALYSIS OF BABY CARRIAGE USER-FRIENDLY DESIGN

    Institute of Scientific and Technical Information of China (English)

    马广韬; 周铎

    2015-01-01

    在婴儿车的设计中,设计者往往重视婴儿车的外观造型而轻视它的人性化设计,这样导致了婴儿车的使用效果欠佳,安全性与功能合理性等方面出现严重的问题。本文以人性化设计为出发点,通过站在亲子性,启发性,安全性,功能性这四个方面来分析与研究婴儿车的人性化设计。旨在使婴儿车的设计更加以人为本,高度体现婴儿车人性化设计理念。使婴儿车的设计能更加满足使用者的情感需求,在功能上也能更合理、安全地为使用者所使用。%In baby carriage design, the designers often pay attention to the appearance molding of the baby carriage but despise the user-friendly design, causing unsatisfactory use effect and serious problem of security and function rationality. This article takes user-friendly design as a starting point, and analyzes and studies the user-friendly design of the baby carriage through the four aspects of parent-child, inspiration, security and functionality. The design is intended to make the baby carriage more people-oriented, and highly manifests the humanized design of the baby carriage, which enables the baby carriage design to satisfy user's emotion demands and makes the function more reasonable and safe for the user.

  2. FAME: Friendly Applied Modelling Environment. Version 2.2 User Manual

    NARCIS (Netherlands)

    Wortelboer FG; Aldenberg T

    1989-01-01

    FAME (Friendly Applied Modelling Environment) is een algemene modelleer omgeving, ontwikkeld voor de dynamische simulatie van waterkwaliteitsmodellen. De modellen worden beschreven als sets van differentiaalvergelijkingen, waarbij van een algemene notatie gebruik wordt gemaakt. Geen kennis van een

  3. PreP+07: improvements of a user friendly tool to preprocess and analyse microarray data

    Directory of Open Access Journals (Sweden)

    Claros M Gonzalo

    2009-01-01

    Full Text Available Abstract Background Nowadays, microarray gene expression analysis is a widely used technology that scientists handle but whose final interpretation usually requires the participation of a specialist. The need for this participation is due to the requirement of some background in statistics that most users lack or have a very vague notion of. Moreover, programming skills could also be essential to analyse these data. An interactive, easy to use application seems therefore necessary to help researchers to extract full information from data and analyse them in a simple, powerful and confident way. Results PreP+07 is a standalone Windows XP application that presents a friendly interface for spot filtration, inter- and intra-slide normalization, duplicate resolution, dye-swapping, error removal and statistical analyses. Additionally, it contains two unique implementation of the procedures – double scan and Supervised Lowess-, a complete set of graphical representations – MA plot, RG plot, QQ plot, PP plot, PN plot – and can deal with many data formats, such as tabulated text, GenePix GPR and ArrayPRO. PreP+07 performance has been compared with the equivalent functions in Bioconductor using a tomato chip with 13056 spots. The number of differentially expressed genes considering p-values coming from the PreP+07 and Bioconductor Limma packages were statistically identical when the data set was only normalized; however, a slight variability was appreciated when the data was both normalized and scaled. Conclusion PreP+07 implementation provides a high degree of freedom in selecting and organizing a small set of widely used data processing protocols, and can handle many data formats. Its reliability has been proven so that a laboratory researcher can afford a statistical pre-processing of his/her microarray results and obtain a list of differentially expressed genes using PreP+07 without any programming skills. All of this gives support to scientists

  4. GAFit: A general-purpose, user-friendly program for fitting potential energy surfaces

    Science.gov (United States)

    Rodríguez-Fernández, Roberto; Pereira, Francisco B.; Marques, Jorge M. C.; Martínez-Núñez, Emilio; Vázquez, Saulo A.

    2017-08-01

    We have developed a software package based on a genetic algorithm that fits an analytic function to a given set of data points. The code, called GAFit, was also interfaced with the CHARMM and MOPAC programs in order to facilitate force field parameterizations and fittings of specific reaction parameters (SRP) for semiempirical Hamiltonians. The present tool may be applied to a wide range of fitting problems, though it has been especially designed to significantly reduce the hard work involved in the development of potential energy surfaces for complex systems. For this purpose, it has been equipped with several programs to help the user in the preparation of the input files. We showcase the application of the computational tool to several chemical-relevant problems: force-field parameterization, with emphasis on nonbonded energy terms or intermolecular potentials, derivation of SRP for semiempirical Hamiltonians, and fittings of generic analytical functions.

  5. Friends sharing opinions: users become co-researchers to evaluate design concepts

    NARCIS (Netherlands)

    Van Doorn, F.A.P.; Gielen, M.A.; Stappers, P.J.

    2013-01-01

    The role of users in design is diversifying and increasing. Besides product evaluations and idea-generation sessions, users can collaborate in research that aims to find requirements for design by acting as researchers themselves. Earlier studies have addressed a variety of reasons why giving users

  6. Electric-powered indoor/outdoor wheelchairs (EPIOCs): users' views of influence on family, friends and carers.

    Science.gov (United States)

    Frank, Andrew; Neophytou, Claudius; Frank, Julia; de Souza, Lorraine

    2010-01-01

    This study explored the effects of electric-powered indoor/outdoor wheelchair (EPIOC) provision to users on their family and carers. EPIOC users receiving their chairs between February and November 2002 (N = 74) were invited to participate in a telephone questionnaire/interview, and 64 agreed. This study examined the responses to the question 'Has the use of your EPIOC affected your family or friends in any way?' and related comments. Interviews were analysed using a qualitative framework approach to identify emergent themes. In addition, the proportion of individuals raising issues related to each theme was determined. Participants were interviewed 10-19 (mean = 14.3) months after chair delivery. The following themes emerged: reduced physical burden on family/friends and increased independence and freedom. However, an EPIOC does not eliminate other practical problems particularly during transportation and negotiating kerbs and slopes. Users also reported anxiety/worry in relationship to EPIOC use, e.g., weather conditions, personal safety (muggings), use of ramps and kerbs. There are considerable benefits to families and carers associated with powered wheelchair use. A reduction in the physical demand for pushing and increased freedom were identified. These benefits appear to outweigh the residual practical difficulties and worries.

  7. Head Strap Double Fluid Level Device: An Innovative and User Friendly Design to Record Natural Head Position (NHP).

    Science.gov (United States)

    John, Lijo; Jose, Nidhin Philip; Shetty, Siddarth

    2015-01-01

    Head positions can be oriented in a standardized position when the patient stands upright and focusses his/her eyes into a point in infinity. This is the natural head position. This position offers the maximum reproducibility and correlates well with the clinical picture offered to the diagnostician. This article describes an innovative and user friendly method to record natural head position using the head strap double fluid level device, a design modified from the popular fluid level device by Showfety, Vig and Matteson.

  8. A user-friendly database of coastal flooding in the United Kingdom from 1915–2014

    Science.gov (United States)

    Haigh, Ivan D.; Wadey, Matthew P.; Gallop, Shari L.; Loehr, Heiko; Nicholls, Robert J.; Horsburgh, Kevin; Brown, Jennifer M.; Bradshaw, Elizabeth

    2015-01-01

    Coastal flooding caused by extreme sea levels can be devastating, with long-lasting and diverse consequences. Historically, the UK has suffered major flooding events, and at present 2.5 million properties and £150 billion of assets are potentially exposed to coastal flooding. However, no formal system is in place to catalogue which storms and high sea level events progress to coastal flooding. Furthermore, information on the extent of flooding and associated damages is not systematically documented nationwide. Here we present a database and online tool called ‘SurgeWatch’, which provides a systematic UK-wide record of high sea level and coastal flood events over the last 100 years (1915-2014). Using records from the National Tide Gauge Network, with a dataset of exceedance probabilities and meteorological fields, SurgeWatch captures information of 96 storms during this period, the highest sea levels they produced, and the occurrence and severity of coastal flooding. The data are presented to be easily assessable and understandable to a range of users including, scientists, coastal engineers, managers and planners and concerned citizens. PMID:25984352

  9. A user-friendly database of coastal flooding in the United Kingdom from 1915-2014.

    Science.gov (United States)

    Haigh, Ivan D; Wadey, Matthew P; Gallop, Shari L; Loehr, Heiko; Nicholls, Robert J; Horsburgh, Kevin; Brown, Jennifer M; Bradshaw, Elizabeth

    2015-01-01

    Coastal flooding caused by extreme sea levels can be devastating, with long-lasting and diverse consequences. Historically, the UK has suffered major flooding events, and at present 2.5 million properties and £150 billion of assets are potentially exposed to coastal flooding. However, no formal system is in place to catalogue which storms and high sea level events progress to coastal flooding. Furthermore, information on the extent of flooding and associated damages is not systematically documented nationwide. Here we present a database and online tool called 'SurgeWatch', which provides a systematic UK-wide record of high sea level and coastal flood events over the last 100 years (1915-2014). Using records from the National Tide Gauge Network, with a dataset of exceedance probabilities and meteorological fields, SurgeWatch captures information of 96 storms during this period, the highest sea levels they produced, and the occurrence and severity of coastal flooding. The data are presented to be easily assessable and understandable to a range of users including, scientists, coastal engineers, managers and planners and concerned citizens.

  10. Tweeting the Friendly Skies: Investigating Information Exchange among Twitter Users about Airlines

    Science.gov (United States)

    Sreenivasan, Nirupama Dharmavaram; Lee, Chei Sian; Goh, Dion Hoe-Lian

    2012-01-01

    Purpose: The purpose of this study is to investigate airline users' microblog postings pertaining to their travel-related information exchange so as to assess their wants, preferences and feedback about airline products and services. Examining such real-time information exchange is important as users rely on this for various purposes such as…

  11. Wordom: a user-friendly program for the analysis of molecular structures, trajectories, and free energy surfaces.

    Science.gov (United States)

    Seeber, Michele; Felline, Angelo; Raimondi, Francesco; Muff, Stefanie; Friedman, Ran; Rao, Francesco; Caflisch, Amedeo; Fanelli, Francesca

    2011-04-30

    Wordom is a versatile, user-friendly, and efficient program for manipulation and analysis of molecular structures and dynamics. The following new analysis modules have been added since the publication of the original Wordom paper in 2007: assignment of secondary structure, calculation of solvent accessible surfaces, elastic network model, motion cross correlations, protein structure network, shortest intra-molecular and inter-molecular communication paths, kinetic grouping analysis, and calculation of mincut-based free energy profiles. In addition, an interface with the Python scripting language has been built and the overall performance and user accessibility enhanced. The source code of Wordom (in the C programming language) as well as documentation for usage and further development are available as an open source package under the GNU General Purpose License from http://wordom.sf.net.

  12. A LabVIEW based user-friendly X-ray phase-contrast imaging system software platform

    CERN Document Server

    Wang, Shenghao; Gao, Kun; Wang, Zhili; Zhang, Can; Yang, Meng; Wu, Zhao; Marcelli, Augusto; Wu, Ziyu

    2014-01-01

    X-ray phase-contrast imaging can provide greatly improved contrast over conventional absorption-based imaging for weakly absorbing samples, such as biological soft tissues and fibre composites. In this manuscript, we introduce an easy and fast way to develop a user-friendly system software platform dedicated for the newly built grating-based X-ray phase-contrast imaging setup at the National Synchrotron Radiation Laboratory, University of Science and Technology of China. Unified management and control upon 21 motorized positioning stages, an ultra-precision piezoelectric translation stage and an X-ray tube are achieved with this platform, the software also covers automatic image acquisition with a flat panel detector for phase-stepping scanning. Moreover, data post-processing module for signals retrieval and other custom features could be realized on it. With a seamless integration of all the necessary functions into an organism, this software platform greatly facilitate activity of the users during experimen...

  13. Back to BaySICS: a user-friendly program for Bayesian Statistical Inference from Coalescent Simulations.

    Science.gov (United States)

    Sandoval-Castellanos, Edson; Palkopoulou, Eleftheria; Dalén, Love

    2014-01-01

    Inference of population demographic history has vastly improved in recent years due to a number of technological and theoretical advances including the use of ancient DNA. Approximate Bayesian computation (ABC) stands among the most promising methods due to its simple theoretical fundament and exceptional flexibility. However, limited availability of user-friendly programs that perform ABC analysis renders it difficult to implement, and hence programming skills are frequently required. In addition, there is limited availability of programs able to deal with heterochronous data. Here we present the software BaySICS: Bayesian Statistical Inference of Coalescent Simulations. BaySICS provides an integrated and user-friendly platform that performs ABC analyses by means of coalescent simulations from DNA sequence data. It estimates historical demographic population parameters and performs hypothesis testing by means of Bayes factors obtained from model comparisons. Although providing specific features that improve inference from datasets with heterochronous data, BaySICS also has several capabilities making it a suitable tool for analysing contemporary genetic datasets. Those capabilities include joint analysis of independent tables, a graphical interface and the implementation of Markov-chain Monte Carlo without likelihoods.

  14. Health Reference Center™: A User-Friendly, Hypertext Information Source for Consumer Health and Patient Education

    OpenAIRE

    1990-01-01

    This demonstration shows a hypertext-linked integrated database consisting of a variety of sources of consumer health information that enables the user to retrieve and understand information more easily than consulting independent sources in the traditional fashion.

  15. QR code based user friendly online bazaar - eTradeWind

    Directory of Open Access Journals (Sweden)

    Shailja Sharma

    2014-06-01

    Full Text Available In the existing online shopping websites there is no such way where user can save the information regarding the particularproduct details. This portal includes all the existing features of online shopping website and in an addition QR (Quick Response Code exists, which generates an unique code for each and every product, by doing so it provides potential to user to scan the QR code by their smart phones and can save the information regarding their fancy product.

  16. QR code based user friendly online bazaar - eTradeWind

    Directory of Open Access Journals (Sweden)

    Shailja Sharma

    2015-11-01

    Full Text Available In the existing online shopping websites there is no such way where user can save the information regarding the particularproduct details. This portal includes all the existing features of online shopping website and in an addition QR (Quick Response Code exists, which generates an unique code for each and every product, by doing so it provides potential to user to scan the QR code by their smart phones and can save the information regarding their fancy product.

  17. Goober: a fully integrated and user-friendly microarray data management and analysis solution for core labs and bench biologists.

    Science.gov (United States)

    Luo, Wen; Gudipati, Murali; Jung, Kevin; Chen, Mao; Marschke, Keith B

    2009-08-23

    Despite the large number of software tools developed to address different areas of microarray data analysis, very few offer an all-in-one solution with little learning curve. For microarray core labs, there are even fewer software packages available to help with their routine but critical tasks, such as data quality control (QC) and inventory management. We have developed a simple-to-use web portal to allow bench biologists to analyze and query complicated microarray data and related biological pathways without prior training. Both experiment-based and gene-based analysis can be easily performed, even for the first-time user, through the intuitive multi-layer design and interactive graphic links. While being friendly to inexperienced users, most parameters in Goober can be easily adjusted via drop-down menus to allow advanced users to tailor their needs and perform more complicated analysis. Moreover, we have integrated graphic pathway analysis into the website to help users examine microarray data within the relevant biological content. Goober also contains features that cover most of the common tasks in microarray core labs, such as real time array QC, data loading, array usage and inventory tracking. Overall, Goober is a complete microarray solution to help biologists instantly discover valuable information from a microarray experiment and enhance the quality and productivity of microarray core labs. The whole package is freely available at http://sourceforge.net/projects/goober. A demo web server is available at http://www.goober-array.org.

  18. GProX, a user-friendly platform for bioinformatics analysis and visualization of quantitative proteomics data.

    Science.gov (United States)

    Rigbolt, Kristoffer T G; Vanselow, Jens T; Blagoev, Blagoy

    2011-08-01

    Recent technological advances have made it possible to identify and quantify thousands of proteins in a single proteomics experiment. As a result of these developments, the analysis of data has become the bottleneck of proteomics experiment. To provide the proteomics community with a user-friendly platform for comprehensive analysis, inspection and visualization of quantitative proteomics data we developed the Graphical Proteomics Data Explorer (GProX)(1). The program requires no special bioinformatics training, as all functions of GProX are accessible within its graphical user-friendly interface which will be intuitive to most users. Basic features facilitate the uncomplicated management and organization of large data sets and complex experimental setups as well as the inspection and graphical plotting of quantitative data. These are complemented by readily available high-level analysis options such as database querying, clustering based on abundance ratios, feature enrichment tests for e.g. GO terms and pathway analysis tools. A number of plotting options for visualization of quantitative proteomics data is available and most analysis functions in GProX create customizable high quality graphical displays in both vector and bitmap formats. The generic import requirements allow data originating from essentially all mass spectrometry platforms, quantitation strategies and software to be analyzed in the program. GProX represents a powerful approach to proteomics data analysis providing proteomics experimenters with a toolbox for bioinformatics analysis of quantitative proteomics data. The program is released as open-source and can be freely downloaded from the project webpage at http://gprox.sourceforge.net.

  19. Smart Dairy Farming in practice : design requirements for user-friendly data based services

    NARCIS (Netherlands)

    Weerdt, C.A. van der; Kort, J.; Boer, J. de; Paradies, G.L.

    2016-01-01

    Key for precision dairy farming is the management of different kinds of (sensor) data from multiple sources and its disclosure to users. The data can be used to implement services that support farmers to care for individual animals and work more effectively. Naturally, these services need to provide

  20. UCTM: A User friendly Configurable Trigger, scaler and delay Module for nuclear and particle physics

    CERN Document Server

    Bourrion, O; Derome, L

    2011-01-01

    A configurable trigger scaler and delay NIM module has been designed to equip nuclear physics experiments and lab teaching classes. It is configurable through a Graphical User Interface (GUI) and provides a large number of possible trigger conditions without any Hardware Description Language (HDL) required knowledge. The design, performances and typical applications are presented.

  1. A User-friendly Interface using Image Processing in Mobile Phones

    DEFF Research Database (Denmark)

    Lynggaard, Per; Skouby, Knud Erik

    smartphone camera that further has the advantage of being familiar to the user. By pointing the camera at a smart object it is recognized and a popup menu for operating it is displayed. However, such a system raises important questions about how to implement it on a smartphone, with respect to processing...

  2. The pursuit of user-friendly medicines : older people in the hot seat

    NARCIS (Netherlands)

    Notenboom, K.

    2017-01-01

    This thesis addresses the user-friendliness of medicines. Using medicines is a complex process during which many difficulties can be experienced, for instance with the opening of packaging, the breakability of tablets or the administration of eye drops. Such practical problems can lead to incorrect

  3. Towards user-friendly spelling with an auditory brain-computer interface: the CharStreamer paradigm.

    Directory of Open Access Journals (Sweden)

    Johannes Höhne

    Full Text Available Realizing the decoding of brain signals into control commands, brain-computer interfaces (BCI aim to establish an alternative communication pathway for locked-in patients. In contrast to most visual BCI approaches which use event-related potentials (ERP of the electroencephalogram, auditory BCI systems are challenged with ERP responses, which are less class-discriminant between attended and unattended stimuli. Furthermore, these auditory approaches have more complex interfaces which imposes a substantial workload on their users. Aiming for a maximally user-friendly spelling interface, this study introduces a novel auditory paradigm: "CharStreamer". The speller can be used with an instruction as simple as "please attend to what you want to spell". The stimuli of CharStreamer comprise 30 spoken sounds of letters and actions. As each of them is represented by the sound of itself and not by an artificial substitute, it can be selected in a one-step procedure. The mental mapping effort (sound stimuli to actions is thus minimized. Usability is further accounted for by an alphabetical stimulus presentation: contrary to random presentation orders, the user can foresee the presentation time of the target letter sound. Healthy, normal hearing users (n = 10 of the CharStreamer paradigm displayed ERP responses that systematically differed between target and non-target sounds. Class-discriminant features, however, varied individually from the typical N1-P2 complex and P3 ERP components found in control conditions with random sequences. To fully exploit the sequential presentation structure of CharStreamer, novel data analysis approaches and classification methods were introduced. The results of online spelling tests showed that a competitive spelling speed can be achieved with CharStreamer. With respect to user rating, it clearly outperforms a control setup with random presentation sequences.

  4. Towards User-Friendly Spelling with an Auditory Brain-Computer Interface: The CharStreamer Paradigm

    Science.gov (United States)

    Höhne, Johannes; Tangermann, Michael

    2014-01-01

    Realizing the decoding of brain signals into control commands, brain-computer interfaces (BCI) aim to establish an alternative communication pathway for locked-in patients. In contrast to most visual BCI approaches which use event-related potentials (ERP) of the electroencephalogram, auditory BCI systems are challenged with ERP responses, which are less class-discriminant between attended and unattended stimuli. Furthermore, these auditory approaches have more complex interfaces which imposes a substantial workload on their users. Aiming for a maximally user-friendly spelling interface, this study introduces a novel auditory paradigm: “CharStreamer”. The speller can be used with an instruction as simple as “please attend to what you want to spell”. The stimuli of CharStreamer comprise 30 spoken sounds of letters and actions. As each of them is represented by the sound of itself and not by an artificial substitute, it can be selected in a one-step procedure. The mental mapping effort (sound stimuli to actions) is thus minimized. Usability is further accounted for by an alphabetical stimulus presentation: contrary to random presentation orders, the user can foresee the presentation time of the target letter sound. Healthy, normal hearing users (n = 10) of the CharStreamer paradigm displayed ERP responses that systematically differed between target and non-target sounds. Class-discriminant features, however, varied individually from the typical N1-P2 complex and P3 ERP components found in control conditions with random sequences. To fully exploit the sequential presentation structure of CharStreamer, novel data analysis approaches and classification methods were introduced. The results of online spelling tests showed that a competitive spelling speed can be achieved with CharStreamer. With respect to user rating, it clearly outperforms a control setup with random presentation sequences. PMID:24886978

  5. A suite of user-friendly global climate models: Hysteresis experiments

    Science.gov (United States)

    Fraedrich, K.

    2012-05-01

    A hierarchy of global spectral circulation models is introduced ranging from the shallow-water system via the primitive-equation dynamical core of the atmosphere to the Planet Simulator as a Global Climate Model (GCM) of Intermediate Complexity (MIC) which can be used to run climate and paleo-climate simulations for time scales up to ten thousand years or more in an acceptable real time. The priorities in development are set to speed, easy handling and portability with a modular structure suitable for problem-dependent configuration. Adaptions exist for the planetary atmospheres of Mars and of Saturn's moon Titan and are being extended. Common coupling interfaces enable the addition of ocean, ice, vegetation models and more. An interactive mode with a Model Starter and a Graphical User Interface (GUI) is available to select a configuration from the available model suite, to set its parameters and inspect atmospheric fields while changing the models' parameters on the fly. This is especially useful for teaching, debugging and tuning of parameterizations. An updated overview of the model suite's features is presented based on the Earth-like climate model Planet Simulator with mixed-layer ocean introducing static and memory hysteresis in terms of a parameter sweep of the solar constant and CO2 concentrations. The static hysteresis experiment demonstrates that the solar constant varying by 20% reveals warm and snowball Earth climate regimes depending on the history of the system. This hysteresis subjected to a thermodynamic analysis shows the following features: i) Both climate regimes are characterized by global mean surface temperature and entropy growing with increasing solar constant. ii) The climate system's efficiency decreases (increases) with increasing solar constant in present-day warm (snowball) climate conditions. iii) Climate transitions near bifurcation points are characterized by high efficiency associated with the system's large distance from the stable

  6. A User-friendly Interface using Image Processing in Mobile Phones

    DEFF Research Database (Denmark)

    Lynggaard, Per; Skouby, Knud Erik

    Future smart homes contain internet of thing objects, or simply smart objects that are able to act pseudo intelligently, communicate and be context aware. Building a portable management system for these smart objects is non-trivial. A technically promising candidate is the use of a common...... smartphone camera that further has the advantage of being familiar to the user. By pointing the camera at a smart object it is recognized and a popup menu for operating it is displayed. However, such a system raises important questions about how to implement it on a smartphone, with respect to processing...... to implement a real time portable user interface for smart homes using a common smartphone camera and the ORB algorithm. Additionally, it has been found that the network bandwidth is at a level acceptable for most common home networks....

  7. Brainstorm: A User-Friendly Application for MEG/EEG Analysis

    Directory of Open Access Journals (Sweden)

    François Tadel

    2011-01-01

    Full Text Available Brainstorm is a collaborative open-source application dedicated to magnetoencephalography (MEG and electroencephalography (EEG data visualization and processing, with an emphasis on cortical source estimation techniques and their integration with anatomical magnetic resonance imaging (MRI data. The primary objective of the software is to connect MEG/EEG neuroscience investigators with both the best-established and cutting-edge methods through a simple and intuitive graphical user interface (GUI.

  8. Brainstorm: a user-friendly application for MEG/EEG analysis.

    Science.gov (United States)

    Tadel, François; Baillet, Sylvain; Mosher, John C; Pantazis, Dimitrios; Leahy, Richard M

    2011-01-01

    Brainstorm is a collaborative open-source application dedicated to magnetoencephalography (MEG) and electroencephalography (EEG) data visualization and processing, with an emphasis on cortical source estimation techniques and their integration with anatomical magnetic resonance imaging (MRI) data. The primary objective of the software is to connect MEG/EEG neuroscience investigators with both the best-established and cutting-edge methods through a simple and intuitive graphical user interface (GUI).

  9. STORMSeq: an open-source, user-friendly pipeline for processing personal genomics data in the cloud.

    Directory of Open Access Journals (Sweden)

    Konrad J Karczewski

    Full Text Available The increasing public availability of personal complete genome sequencing data has ushered in an era of democratized genomics. However, read mapping and variant calling software is constantly improving and individuals with personal genomic data may prefer to customize and update their variant calls. Here, we describe STORMSeq (Scalable Tools for Open-Source Read Mapping, a graphical interface cloud computing solution that does not require a parallel computing environment or extensive technical experience. This customizable and modular system performs read mapping, read cleaning, and variant calling and annotation. At present, STORMSeq costs approximately $2 and 5-10 hours to process a full exome sequence and $30 and 3-8 days to process a whole genome sequence. We provide this open-access and open-source resource as a user-friendly interface in Amazon EC2.

  10. STORMSeq: an open-source, user-friendly pipeline for processing personal genomics data in the cloud.

    Science.gov (United States)

    Karczewski, Konrad J; Fernald, Guy Haskin; Martin, Alicia R; Snyder, Michael; Tatonetti, Nicholas P; Dudley, Joel T

    2014-01-01

    The increasing public availability of personal complete genome sequencing data has ushered in an era of democratized genomics. However, read mapping and variant calling software is constantly improving and individuals with personal genomic data may prefer to customize and update their variant calls. Here, we describe STORMSeq (Scalable Tools for Open-Source Read Mapping), a graphical interface cloud computing solution that does not require a parallel computing environment or extensive technical experience. This customizable and modular system performs read mapping, read cleaning, and variant calling and annotation. At present, STORMSeq costs approximately $2 and 5-10 hours to process a full exome sequence and $30 and 3-8 days to process a whole genome sequence. We provide this open-access and open-source resource as a user-friendly interface in Amazon EC2.

  11. A LabVIEW based user-friendly nano-CT image alignment and 3D reconstruction platform

    CERN Document Server

    Wang, Shenghao; Wang, Zhili; Gao, Kun; Wu, Zhao; Zhu, Peiping; Wu, Ziyu

    2014-01-01

    X-ray nanometer computed tomography (nano-CT) offers applications and opportunities in many scientific researches and industrial areas. Here we present a user-friendly and fast LabVIEW based package running, after acquisition of the raw projection images, a procedure to obtain the inner structure of the sample under analysis. At first, a reliable image alignment procedure fixes possible misalignments among image series due to mechanical errors, thermal expansion and other external contributions, then a novel fast parallel beam 3D reconstruction performs the tomographic reconstruction. The remarkable improved reconstruction after the image calibration confirms the fundamental role of the image alignment procedure. It minimizes blurring and additional streaking artifacts present in a reconstructed slice that cause loss of information and faked structures in the observed material. The nano-CT image alignment and 3D reconstruction LabVIEW package significantly reducing the data process, makes faster and easier th...

  12. Methods of Developing User-Friendly Keys to Identify Green Sea Turtles (Chelonia mydas L. from Photographs

    Directory of Open Access Journals (Sweden)

    Jane R. Lloyd

    2012-01-01

    Full Text Available Identifying individual animals is important in understanding their ecology and behaviour, as well as providing estimates of population sizes for conservation efforts. We produce identification keys from photographs of green sea turtles to identify them while foraging in Akumal Bay, Mexico. We create three keys, which (a minimise the length of the key, (b present the most obvious differential characteristics first, and (c remove the strict dichotomy from key b. Keys were capable of identifying >99% of turtles in >2500 photographs during the six-month study period. The keys differed significantly in success rate for students to identify individual turtles, with key (c being the best with >70% success and correctly being followed further than other keys before making a mistake. User-friendly keys are, therefore, a suitable method for the photographic identification of turtles and could be used for other large marine vertebrates in conservation or behavioural studies.

  13. SP-Designer: a user-friendly program for designing species-specific primer pairs from DNA sequence alignments.

    Science.gov (United States)

    Villard, Pierre; Malausa, Thibaut

    2013-07-01

    SP-Designer is an open-source program providing a user-friendly tool for the design of specific PCR primer pairs from a DNA sequence alignment containing sequences from various taxa. SP-Designer selects PCR primer pairs for the amplification of DNA from a target species on the basis of several criteria: (i) primer specificity, as assessed by interspecific sequence polymorphism in the annealing regions, (ii) the biochemical characteristics of the primers and (iii) the intended PCR conditions. SP-Designer generates tables, detailing the primer pair and PCR characteristics, and a FASTA file locating the primer sequences in the original sequence alignment. SP-Designer is Windows-compatible and freely available from http://www2.sophia.inra.fr/urih/sophia_mart/sp_designer/info_sp_designer.php. © 2013 John Wiley & Sons Ltd.

  14. CANGS: a user-friendly utility for processing and analyzing 454 GS-FLX data in biodiversity studies

    Directory of Open Access Journals (Sweden)

    Schlötterer Christian

    2010-01-01

    Full Text Available Abstract Background Next generation sequencing (NGS technologies have substantially increased the sequence output while the costs were dramatically reduced. In addition to the use in whole genome sequencing, the 454 GS-FLX platform is becoming a widely used tool for biodiversity surveys based on amplicon sequencing. In order to use NGS for biodiversity surveys, software tools are required, which perform quality control, trimming of the sequence reads, removal of PCR primers, and generation of input files for downstream analyses. A user-friendly software utility that carries out these steps is still lacking. Findings We developed CANGS (Cleaning and Analyzing Next Generation Sequences a flexible and user-friendly integrated software utility: CANGS is designed for amplicon based biodiversity surveys using the 454 sequencing platform. CANGS filters low quality sequences, removes PCR primers, filters singletons, identifies barcodes, and generates input files for downstream analyses. The downstream analyses rely either on third party software (e.g.: rarefaction analyses or CANGS-specific scripts. The latter include modules linking 454 sequences with the name of the closest taxonomic reference retrieved from the NCBI database and the sequence divergence between them. Our software can be easily adapted to handle sequencing projects with different amplicon sizes, primer sequences, and quality thresholds, which makes this software especially useful for non-bioinformaticians. Conclusion CANGS performs PCR primer clipping, filtering of low quality sequences, links sequences to NCBI taxonomy and provides input files for common rarefaction analysis software programs. CANGS is written in Perl and runs on Mac OS X/Linux and is available at http://i122server.vu-wien.ac.at/pop/software.html

  15. User-friendly Establishment of Trust in Distributed Home Automation Networks

    DEFF Research Database (Denmark)

    Solberg Hjorth, Theis; Torbensen, Rune; Madsen, Per Printz

    2014-01-01

    Current wireless technologies use a variety of methods to locally exchange and verify credentials between devices to establish trusted relationships. Scenarios in home automation networks also require this capability over the Internet, but the necessary involvement of non-expert users to setup...... these relationships can lead to misconfiguration or breaches of security. We outline a security system for Home Automation called Trusted Domain that can establish and maintain cryptographically secure relationships between devices connected via IP-based networks and the Internet. Trust establishment is presented...

  16. User-friendly establishment of trust in distributed home automation networks

    DEFF Research Database (Denmark)

    Solberg Hjorth, Theis; Madsen, Per Printz; Torbensen, Rune Sonnich

    2012-01-01

    Current wireless technologies use a variety of methods to locally exchange and verify credentials between devices to establish trusted relationships. Scenarios in home automation networks also require this capability over the Internet, but the necessary involvement of non-expert users to setup...... these relationships can lead to misconfiguration or breaches of security. We outline a security system for Home Automation called Trusted Domain that can establish and maintain cryptographically secure relationships between devices connected via IP-based networks and the Internet. Trust establishment is presented...

  17. Grasp specific and user friendly interface design for myoelectric hand prostheses.

    Science.gov (United States)

    Mohammadi, Alireza; Lavranos, Jim; Howe, Rob; Choong, Peter; Oetomo, Denny

    2017-07-01

    This paper presents the design and characterisation of a hand prosthesis and its user interface, focusing on performing the most commonly used grasps in activities of daily living (ADLs). Since the operation of a multi-articulated powered hand prosthesis is difficult to learn and master, there is a significant rate of abandonment by amputees in preference for simpler devices. In choosing so, amputees chose to live with fewer features in their prosthesis that would more reliably perform the basic operations. In this paper, we look simultaneously at a hand prosthesis design method that aims for a small number of grasps, a low complexity user interface and an alternative method to the current use of EMG as a preshape selection method through the use of a simple button; to enable amputees to get to and execute the intended hand movements intuitively, quickly and reliably. An experiment is reported at the end of the paper comparing the speed and accuracy with which able-bodied naive subjects are able to select the intended preshapes through the use of a simplified EMG method and a simple button. It is shown that the button was significantly superior in the speed of successful task completion and marginally superior in accuracy (success of first attempt).

  18. A user-friendly menu-driven language-free laser characteristics curves graphing program

    Science.gov (United States)

    Klutz, Glenn

    1990-01-01

    In the selection of laser materials to be used as active sensors, it is essential to know how various factors of the specific material composition interact. Questions such as how does the rod size and frequency or absorption relate and how might this be affected by temperature variations must be answered before the materials are selected. A menu-driven language-free program was developed that would graph the interrelationship of many physical parameters of laser materials. This program reduced or removed the requirement that all users be competent in FORTRAN. A menu-driven language-free program was then developed that requires the use of a microcomputer to graph a two-dimensional display of data. The ability to graph more than one graph-line on the same chart was accomplished. The program is now generic in that it will take any data file whether in the data base or not. The program generates the format for the data read statement if it is not contained in the file header and the user does not know how to write them.

  19. A Student-Friendly Graphical User Interface to Extract Data from Remote Sensing Level-2 Products.

    Science.gov (United States)

    Bernardello, R.

    2016-02-01

    Remote sensing era has provided an unprecedented amount of publicly available data. The United States National Aeronautics and Space Administration Goddard Space Flight Center (NASA-GSFC) has achieved remarkable results in the distribution of these data to the scientific community through the OceanColor web page (http://oceancolor.gsfc.nasa.gov/). However, the access to these data, is not straightforward and needs a certain investment of time in learning the use of existing software. Satellite sensors acquire raw data that are processed through several steps towards a format usable by the scientific community. These products are distributed in Hierarchical Data Format (HDF) which often represents the first obstacle for students, teachers and scientists not used to deal with extensive matrices. We present here SATellite data PROcessing (SATPRO) a newly developed Graphical User Interface (GUI) designed in MATLAB environment to provide an easy, immediate yet reliable way to select and extract Level-2 data from NASA SeaWIFS and MODIS-Aqua databases for oceanic surface temperature and chlorophyll. Since no previous experience with MATLAB is required, SATPRO allows the user to explore the available dataset without investing any software-learning time. SATPRO is an ideal tool to introduce undergraduate students to the use of remote sensing data in oceanography and can also be useful for research projects at the graduate level.

  20. The VERCE Science Gateway: enabling user friendly seismic waves simulations across European HPC infrastructures

    Science.gov (United States)

    Spinuso, Alessandro; Krause, Amy; Ramos Garcia, Clàudia; Casarotti, Emanuele; Magnoni, Federica; Klampanos, Iraklis A.; Frobert, Laurent; Krischer, Lion; Trani, Luca; David, Mario; Leong, Siew Hoon; Muraleedharan, Visakh

    2014-05-01

    The EU-funded project VERCE (Virtual Earthquake and seismology Research Community in Europe) aims to deploy technologies which satisfy the HPC and data-intensive requirements of modern seismology. As a result of VERCE's official collaboration with the EU project SCI-BUS, access to computational resources, like local clusters and international infrastructures (EGI and PRACE), is made homogeneous and integrated within a dedicated science gateway based on the gUSE framework. In this presentation we give a detailed overview on the progress achieved with the developments of the VERCE Science Gateway, according to a use-case driven implementation strategy. More specifically, we show how the computational technologies and data services have been integrated within a tool for Seismic Forward Modelling, whose objective is to offer the possibility to perform simulations of seismic waves as a service to the seismological community. We will introduce the interactive components of the OGC map based web interface and how it supports the user with setting up the simulation. We will go through the selection of input data, which are either fetched from federated seismological web services, adopting community standards, or provided by the users themselves by accessing their own document data store. The HPC scientific codes can be selected from a number of waveform simulators, currently available to the seismological community as batch tools or with limited configuration capabilities in their interactive online versions. The results will be staged out from the HPC via a secure GridFTP transfer to a VERCE data layer managed by iRODS. The provenance information of the simulation will be automatically cataloged by the data layer via NoSQL techonologies. We will try to demonstrate how data access, validation and visualisation can be supported by a general purpose provenance framework which, besides common provenance concepts imported from the OPM and the W3C-PROV initiatives, also offers

  1. EDENetworks: a user-friendly software to build and analyse networks in biogeography, ecology and population genetics.

    Science.gov (United States)

    Kivelä, Mikko; Arnaud-Haond, Sophie; Saramäki, Jari

    2015-01-01

    The recent application of graph-based network theory analysis to biogeography, community ecology and population genetics has created a need for user-friendly software, which would allow a wider accessibility to and adaptation of these methods. EDENetworks aims to fill this void by providing an easy-to-use interface for the whole analysis pipeline of ecological and evolutionary networks starting from matrices of species distributions, genotypes, bacterial OTUs or populations characterized genetically. The user can choose between several different ecological distance metrics, such as Bray-Curtis or Sorensen distance, or population genetic metrics such as FST or Goldstein distances, to turn the raw data into a distance/dissimilarity matrix. This matrix is then transformed into a network by manual or automatic thresholding based on percolation theory or by building the minimum spanning tree. The networks can be visualized along with auxiliary data and analysed with various metrics such as degree, clustering coefficient, assortativity and betweenness centrality. The statistical significance of the results can be estimated either by resampling the original biological data or by null models based on permutations of the data. © 2014 John Wiley & Sons Ltd.

  2. Cube sugar-like sponge/polymer brush composites for portable and user-friendly heavy metal ion adsorbents.

    Science.gov (United States)

    Bae, Ji Young; Lee, Ha-Jin; Choi, Won San

    2016-12-15

    Portable, non-toxic, and user-friendly sponge composites decorated with polyelectrolyte (PE) brushes were developed for the fast and efficient removal of heavy metal ions from waste water or drinking water. The polyacrylamide (PAM) and polyacrylic acid (PAA) brushes were grafted onto the sponge via "grafting-from" polymerization. For the polyethyleneimine (PEI) brush, "grafting-to" polymerization was used. A polydopamine (Pdop) layer was first coated on the sponge. Then, PEI was grafted onto the Pdop-coated sponge via a Michael addition reaction. The PEI-grafted sponge exhibited the best adsorption capacity and the fastest reaction rate of all the brushes due to the numerous adsorption sites of the PEI. The adsorption performance of two different PEI-grafted sponges depended on the molecular weight (MW) of the PEI. Simply by being dipped into a glass of water, non-toxic PEI-grafted sponge instantly removed the low concentration heavy metal ions, demonstrating a practical application for individual users. Copyright © 2016 Elsevier B.V. All rights reserved.

  3. A user-friendly, open-source tool to project impact and cost of diagnostic tests for tuberculosis.

    Science.gov (United States)

    Dowdy, David W; Andrews, Jason R; Dodd, Peter J; Gilman, Robert H

    2014-06-04

    Most models of infectious diseases, including tuberculosis (TB), do not provide results customized to local conditions. We created a dynamic transmission model to project TB incidence, TB mortality, multidrug-resistant (MDR) TB prevalence, and incremental costs over 5 years after scale-up of nine alternative diagnostic strategies. A corresponding web-based interface allows users to specify local costs and epidemiology. In settings with little capacity for up-front investment, same-day microscopy had the greatest impact on TB incidence and became cost-saving within 5 years if delivered at $10/test. With greater initial investment, population-level scale-up of Xpert MTB/RIF or microcolony-based culture often averted 10 times more TB cases than narrowly-targeted strategies, at minimal incremental long-term cost. Xpert for smear-positive TB had reasonable impact on MDR-TB incidence, but at substantial price and little impact on overall TB incidence and mortality. This user-friendly modeling framework improves decision-makers' ability to evaluate the local impact of TB diagnostic strategies.

  4. USER FRIENDLY OPEN GIS TOOL FOR LARGE SCALE DATA ASSIMILATION – A CASE STUDY OF HYDROLOGICAL MODELLING

    Directory of Open Access Journals (Sweden)

    P. K. Gupta

    2012-08-01

    Full Text Available Open source software (OSS coding has tremendous advantages over proprietary software. These are primarily fuelled by high level programming languages (JAVA, C++, Python etc... and open source geospatial libraries (GDAL/OGR, GEOS, GeoTools etc.. Quantum GIS (QGIS is a popular open source GIS package, which is licensed under GNU GPL and is written in C++. It allows users to perform specialised tasks by creating plugins in C++ and Python. This research article emphasises on exploiting this capability of QGIS to build and implement plugins across multiple platforms using the easy to learn – Python programming language. In the present study, a tool has been developed to assimilate large spatio-temporal datasets such as national level gridded rainfall, temperature, topographic (digital elevation model, slope, aspect, landuse/landcover and multi-layer soil data for input into hydrological models. At present this tool has been developed for Indian sub-continent. An attempt is also made to use popular scientific and numerical libraries to create custom applications for digital inclusion. In the hydrological modelling calibration and validation are important steps which are repetitively carried out for the same study region. As such the developed tool will be user friendly and used efficiently for these repetitive processes by reducing the time required for data management and handling. Moreover, it was found that the developed tool can easily assimilate large dataset in an organised manner.

  5. Identification of minimal eukaryotic introns through GeneBase, a user-friendly tool for parsing the NCBI Gene databank.

    Science.gov (United States)

    Piovesan, Allison; Caracausi, Maria; Ricci, Marco; Strippoli, Pierluigi; Vitale, Lorenza; Pelleri, Maria Chiara

    2015-12-01

    We have developed GeneBase, a full parser of the National Center for Biotechnology Information (NCBI) Gene database, which generates a fully structured local database with an intuitive user-friendly graphic interface for personal computers. Features of all the annotated eukaryotic genes are accessible through three main software tables, including for each entry details such as the gene summary, the gene exon/intron structure and the specific Gene Ontology attributions. The structuring of the data, the creation of additional calculation fields and the integration with nucleotide sequences allow users to make many types of comparisons and calculations that are useful for data retrieval and analysis. We provide an original example analysis of the existing introns across all the available species, through which the classic biological problem of the 'minimal intron' may find a solution using available data. Based on all currently available data, we can define the shortest known eukaryotic GT-AG intron length, setting the physical limit at the 30 base pair intron belonging to the human MST1L gene. This 'model intron' will shed light on the minimal requirement elements of recognition used for conventional splicing functioning. Remarkably, this size is indeed consistent with the sum of the splicing consensus sequence lengths.

  6. A user-friendly LabVIEW software platform for grating based X-ray phase-contrast imaging.

    Science.gov (United States)

    Wang, Shenghao; Han, Huajie; Gao, Kun; Wang, Zhili; Zhang, Can; Yang, Meng; Wu, Zhao; Wu, Ziyu

    2015-01-01

    X-ray phase-contrast imaging can provide greatly improved contrast over conventional absorption-based imaging for weakly absorbing samples, such as biological soft tissues and fibre composites. In this study, we introduced an easy and fast way to develop a user-friendly software platform dedicated to the new grating-based X-ray phase-contrast imaging setup at the National Synchrotron Radiation Laboratory of the University of Science and Technology of China. The control of 21 motorized stages, of a piezoelectric stage and of an X-ray tube are achieved with this software, it also covers image acquisition with a flat panel detector for automatic phase stepping scan. Moreover, a data post-processing module for signals retrieval and other custom features are in principle available. With a seamless integration of all the necessary functions in one software package, this platform greatly facilitate users' activities during experimental runs with this grating based X-ray phase contrast imaging setup.

  7. A user-friendly SSVEP-based brain-computer interface using a time-domain classifier

    Science.gov (United States)

    Luo, An; Sullivan, Thomas J.

    2010-04-01

    We introduce a user-friendly steady-state visual evoked potential (SSVEP)-based brain-computer interface (BCI) system. Single-channel EEG is recorded using a low-noise dry electrode. Compared to traditional gel-based multi-sensor EEG systems, a dry sensor proves to be more convenient, comfortable and cost effective. A hardware system was built that displays four LED light panels flashing at different frequencies and synchronizes with EEG acquisition. The visual stimuli have been carefully designed such that potential risk to photosensitive people is minimized. We describe a novel stimulus-locked inter-trace correlation (SLIC) method for SSVEP classification using EEG time-locked to stimulus onsets. We studied how the performance of the algorithm is affected by different selection of parameters. Using the SLIC method, the average light detection rate is 75.8% with very low error rates (an 8.4% false positive rate and a 1.3% misclassification rate). Compared to a traditional frequency-domain-based method, the SLIC method is more robust (resulting in less annoyance to the users) and is also suitable for irregular stimulus patterns.

  8. A 'user friendly' geographic information system in a color interactive digital image processing system environment

    Science.gov (United States)

    Campbell, W. J.; Goldberg, M.

    1982-01-01

    NASA's Eastern Regional Remote Sensing Applications Center (ERRSAC) has recognized the need to accommodate spatial analysis techniques in its remote sensing technology transfer program. A computerized Geographic Information System to incorporate remotely sensed data, specifically Landsat, with other relevant data was considered a realistic approach to address a given resource problem. Questions arose concerning the selection of a suitable available software system to demonstrate, train, and undertake demonstration projects with ERRSAC's user community. The very specific requirements for such a system are discussed. The solution found involved the addition of geographic information processing functions to the Interactive Digital Image Manipulation System (IDIMS). Details regarding the functions of the new integrated system are examined along with the characteristics of the software.

  9. Key Elements of the User-Friendly, GFDL SKYHI General Circulation Model

    Directory of Open Access Journals (Sweden)

    Richard S. Hemler

    2000-01-01

    Full Text Available Over the past seven years, the portability of the GFDL SKYHI general circulation model has greatly increased. Modifications to the source code have allowed SKYHI to be run on the GFDL Cray Research PVP machines, the TMC CM-5 machine at Los Alamos National Laboratory, and more recently on the GFDL 40-processor Cray Research T3E system. At the same time, changes have been made to the model to make it more usable and flexible. Because of the reduction of the human resources available to manage and analyze scientific experiments, it is no longer acceptable to consider only the optimization of computer resources when producing a research code; one must also consider the availability and cost of the people necessary to maintain, modify and use the model as an investigative tool, and include these factors in defining the form of the model code. The new SKYHI model attempts to strike a balance between the optimization of the use of machine resources (CPU time, memory, disc and the optimal use of human resources (ability to understand code, ability to modify code, ability to perturb code to do experiments, ability to run code on different platforms. Two of the key features that make the new SKYHI code more usable and flexible are the archiving package and the user variable block. The archiving package is used to manage the writing of all archive files, which contain data for later analysis. The model-supplied user variable block allows the easy inclusion of any new variables needed for particular experiments.

  10. The VERCE Science Gateway: Enabling User Friendly HPC Seismic Wave Simulations.

    Science.gov (United States)

    Casarotti, E.; Spinuso, A.; Matser, J.; Leong, S. H.; Magnoni, F.; Krause, A.; Garcia, C. R.; Muraleedharan, V.; Krischer, L.; Anthes, C.

    2014-12-01

    The EU-funded project VERCE (Virtual Earthquake and seismology Research Community in Europe) aims to deploy technologies which satisfy the HPC and data-intensive requirements of modern seismology.As a result of VERCE official collaboration with the EU project SCI-BUS, access to computational resources, like local clusters and international infrastructures (EGI and PRACE), is made homogeneous and integrated within a dedicated science gateway based on the gUSE framework. In this presentation we give a detailed overview on the progress achieved with the developments of the VERCE Science Gateway, according to a use-case driven implementation strategy. More specifically, we show how the computational technologies and data services have been integrated within a tool for Seismic Forward Modelling, whose objective is to offer the possibility to performsimulations of seismic waves as a service to the seismological community.We will introduce the interactive components of the OGC map based web interface and how it supports the user with setting up the simulation. We will go through the selection of input data, which are either fetched from federated seismological web services, adopting community standards, or provided by the users themselves by accessing their own document data store. The HPC scientific codes can be selected from a number of waveform simulators, currently available to the seismological community as batch tools or with limited configuration capabilities in their interactive online versions.The results will be staged out via a secure GridFTP transfer to a VERCE data layer managed by iRODS. The provenance information of the simulation will be automatically cataloged by the data layer via NoSQL techonologies.Finally, we will show the example of how the visualisation output of the gateway could be enhanced by the connection with immersive projection technology at the Virtual Reality and Visualisation Centre of Leibniz Supercomputing Centre (LRZ).

  11. CANEapp: a user-friendly application for automated next generation transcriptomic data analysis.

    Science.gov (United States)

    Velmeshev, Dmitry; Lally, Patrick; Magistri, Marco; Faghihi, Mohammad Ali

    2016-01-13

    Next generation sequencing (NGS) technologies are indispensable for molecular biology research, but data analysis represents the bottleneck in their application. Users need to be familiar with computer terminal commands, the Linux environment, and various software tools and scripts. Analysis workflows have to be optimized and experimentally validated to extract biologically meaningful data. Moreover, as larger datasets are being generated, their analysis requires use of high-performance servers. To address these needs, we developed CANEapp (application for Comprehensive automated Analysis of Next-generation sequencing Experiments), a unique suite that combines a Graphical User Interface (GUI) and an automated server-side analysis pipeline that is platform-independent, making it suitable for any server architecture. The GUI runs on a PC or Mac and seamlessly connects to the server to provide full GUI control of RNA-sequencing (RNA-seq) project analysis. The server-side analysis pipeline contains a framework that is implemented on a Linux server through completely automated installation of software components and reference files. Analysis with CANEapp is also fully automated and performs differential gene expression analysis and novel noncoding RNA discovery through alternative workflows (Cuffdiff and R packages edgeR and DESeq2). We compared CANEapp to other similar tools, and it significantly improves on previous developments. We experimentally validated CANEapp's performance by applying it to data derived from different experimental paradigms and confirming the results with quantitative real-time PCR (qRT-PCR). CANEapp adapts to any server architecture by effectively using available resources and thus handles large amounts of data efficiently. CANEapp performance has been experimentally validated on various biological datasets. CANEapp is available free of charge at http://psychiatry.med.miami.edu/research/laboratory-of-translational-rna-genomics/CANE-app . We

  12. A user-friendly automated port placement planning system for laparoscopic robotic surgery

    Science.gov (United States)

    Torres, Luis G.; Azimian, Hamidreza; Enquobahrie, Andinet

    2014-03-01

    Laparoscopic surgery is a minimally invasive surgical approach in which surgical instruments are passed through ports placed at small incisions. This approach can benefit patients by reducing recovery times and scars. Surgeons have gained greater dexterity, accuracy, and vision through adoption of robotic surgical systems. However, in some cases a preselected set of ports cannot be accommodated by the robot; the robot's arms may cause collisions during the procedure, or the surgical targets may not be reachable through the selected ports. In this case, the surgeon must either make more incisions for more ports, or even abandon the laparoscopic approach entirely. To assist in this, we are building an easytouse system which, given a surgical task and preoperative medical images of the patient, will recommend a suitable port placement plan for the robotic surgery. This work bears two main contributions: 1) a high level user interface that assists the surgeon in operating the complicated underlying planning algorithm; and 2) an interface to assist the surgical team in implementation of the recommended plan in the operating room. We believe that such an automated port placement system would reduce setup time for robotic surgery and reduce the morbidity to patients caused by unsuitable surgical port placement.

  13. Speeding up the screening of steroids in urine: development of a user-friendly library.

    Science.gov (United States)

    Galesio, M; López-Fdez, H; Reboiro-Jato, M; Gómez-Meire, Silvana; Glez-Peña, D; Fdez-Riverola, F; Lodeiro, Carlos; Diniz, M E; Capelo, J L

    2013-12-11

    This work presents a novel database search engine - MLibrary - designed to assist the user in the detection and identification of androgenic anabolic steroids (AAS) and its metabolites by matrix assisted laser desorption/ionization (MALDI) and mass spectrometry-based strategies. The detection of the AAS in the samples was accomplished by searching (i) the mass spectrometric (MS) spectra against the library developed to identify possible positives and (ii) by comparison of the tandem mass spectrometric (MS/MS) spectra produced after fragmentation of the possible positives with a complete set of spectra that have previously been assigned to the software. The urinary screening for anabolic agents plays a major role in anti-doping laboratories as they represent the most abused drug class in sports. With the help of the MLibrary software application, the use of MALDI techniques for doping control is simplified and the time for evaluation and interpretation of the results is reduced. To do so, the search engine takes as input several MALDI-TOF-MS and MALDI-TOF-MS/MS spectra. It aids the researcher in an automatic mode by identifying possible positives in a single MS analysis and then confirming their presence in tandem MS analysis by comparing the experimental tandem mass spectrometric data with the database. Furthermore, the search engine can, potentially, be further expanded to other compounds in addition to AASs. The applicability of the MLibrary tool is shown through the analysis of spiked urine samples.

  14. MINErosion 3: A user friendly hillslope model for predicting erosion from steep post-mining landscapes in Central Queensland, Australia.

    Science.gov (United States)

    So, Hwat-Bing; Khalifa, Ashraf; Carroll, Chris; Yu, Bofu

    2010-05-01

    Open-cut coal mining in Central Queensland involves the breaking up of overburden that overlies the coal seams using explosives, followed by removal with draglines which results in the formation of extensive overburden spoil-piles with steep slopes at the angle of repose (approximately 75 % or 37o). These spoil-piles are found in long multiple rows, with heights of up to 60 or 70 m above the original landscapes. They are generally highly saline and dispersive and hence highly erosive. Legislation requires that these spoil-piles be rehabilitated into a stable self sustaining ecosystem with no off-site pollution. The first stage in the rehabilitation of these landscapes is the lowering of slopes to create a landscape that is stable against geotechnical failure and erosion. This is followed by revegetation generally with grasses as pioneer vegetation to further reduce erosion and a mixture of native shrubs and trees. Minimizing erosion and excessive on-site discharges of sediment into the working areas may result in the temporary cessation of mining operation with significant financial consequences, while off site discharges may breach the mining lease conditions. The average cost of rehabilitation is around 22,000 per ha. With more than 50,000 ha of such spoil-piles in Queensland at present, the total cost of rehabilitation facing the industry is very high. Most of this comprised the cost of reshaping the landscape, largely associated with the amount of material movement necessary to achieve the desired landscape. Since soil and spoil-piles vary greatly in their erodibilities, a reliable and accurate method is required to determine a cost effective combination of slope length, slope gradient and vegetation that will result in acceptable rates of erosion. A user friendly hillslope computer package MINErosion 3, was developed to predict potential erosion to select suitable combinations of landscape design parameters (slope gradient, slope length and vegetation cover

  15. Editorial: a scientifically rigorous and user-friendly Rangeland Ecology & Management

    Science.gov (United States)

    Rangeland Ecology and Management (REM) is the premier journal for communication of science-based knowledge and for fostering both innovation and rigor in our stewardship of the world’s rangelands. REM is critical to the mission of the Society for Range Management and has had increasing scientific im...

  16. swinger: a user-friendly computer program to establish captive breeding groups that minimize relatedness without pedigree information.

    Science.gov (United States)

    Sandoval-Castillo, Jonathan; Attard, Catherine R M; Marri, Shashikanth; Brauer, Chris J; Möller, Luciana M; Beheregaray, Luciano B

    2017-03-01

    Captive breeding programmes are often a necessity for the continued persistence of a population or species. They typically have the goal of maintaining genetic diversity and minimizing inbreeding. However, most captive breeding programmes have been based on the assumption that the founding breeders are unrelated and outbred, even though in situ anthropogenic impacts often mean these founders may have high relatedness and substantial inbreeding. In addition, polygamous group-breeding species in captivity often have uncertain pedigrees, making it difficult to select the group composition for subsequent breeding. Molecular-based estimates of relatedness and inbreeding may instead be used to select breeding groups (≥two individuals) that minimize relatedness and filter out inbred individuals. swinger constructs breeding groups based on molecular estimates of relatedness and inbreeding. The number of possible combinations of breeding groups quickly becomes intractable by hand. swinger was designed to overcome this major issue in ex situ conservation biology. The user can specify parameters within swinger to reach breeding solutions that suit the mating system of the target species and available resources. We provide evidence of the efficiency of the software with an empirical example and using simulations. The only data required are a typical molecular marker data set, such as a microsatellite or SNP data set, from which estimates of inbreeding and pairwise relatedness may be obtained. Such molecular data sets are becoming easier to gather from non-model organisms with next-generation sequencing technology. swinger is an open-source software with a user-friendly interface and is available at http://www.molecularecology.flinders.edu.au/molecular-ecology-lab/software/swinger/swinger/ and https://github.com/Yuma248/Swinger.

  17. User-Friendly End Station at the ALS for Nanostructure Characterization

    Energy Technology Data Exchange (ETDEWEB)

    F. J. Himpsel; P. Alivisatos; T. Callcott; J. Carlisle; J. D. Denlinger; D. E. Eastman; D. Ederer; Z. Hussain; L.J. Terminello; T. Van Buuren; R. S. Williams

    2006-07-05

    This is a construction project for an end station at the ALS, which is optimized for measuring NEXAFS of nanostructures with fluorescence detection. Compared to the usual electron yield detection, fluorescence is able to probe buried structures and is sensitive to dilute species, such as nanostructures supported on a substrate. Since the quantum yield for fluorescence is 10{sup -4}-10{sup -5} times smaller than for electrons in the soft x-ray regime, such an end station requires bright undulator beamlines at the ALS. In order to optimize the setup for a wide range of applications, two end stations were built: (1) A simple, mobile chamber with efficient photon detection (>10{sup 4} times the solid angle collection of fluorescence spectrographs) and a built-in magnet for MCD measurements at EPU beamlines (Fig. 1 left). It allows rapid mapping the electronic states of nanostructures (nanocrystals, nanowires, tailored magnetic materials, buried interfaces, biologically-functionalized surfaces). It was used with BL 8.0 (linear polarized undulator) and BL 4.0 (variable polarization). (2) A sophisticated, stationary end station operating at Beamline 8.0 (Fig. 1 right). It contains an array of surface characterization instruments and a micro-focus capability for scanning across graded samples (wedges for thickness variation, stoichiometry gradients, and general variations of the sample preparation conditions for optimizing nanostructures).

  18. SigmoID: a user-friendly tool for improving bacterial genome annotation through analysis of transcription control signals

    Directory of Open Access Journals (Sweden)

    Yevgeny Nikolaichik

    2016-05-01

    Full Text Available The majority of bacterial genome annotations are currently automated and based on a ‘gene by gene’ approach. Regulatory signals and operon structures are rarely taken into account which often results in incomplete and even incorrect gene function assignments. Here we present SigmoID, a cross-platform (OS X, Linux and Windows open-source application aiming at simplifying the identification of transcription regulatory sites (promoters, transcription factor binding sites and terminators in bacterial genomes and providing assistance in correcting annotations in accordance with regulatory information. SigmoID combines a user-friendly graphical interface to well known command line tools with a genome browser for visualising regulatory elements in genomic context. Integrated access to online databases with regulatory information (RegPrecise and RegulonDB and web-based search engines speeds up genome analysis and simplifies correction of genome annotation. We demonstrate some features of SigmoID by constructing a series of regulatory protein binding site profiles for two groups of bacteria: Soft Rot Enterobacteriaceae (Pectobacterium and Dickeya spp. and Pseudomonas spp. Furthermore, we inferred over 900 transcription factor binding sites and alternative sigma factor promoters in the annotated genome of Pectobacterium atrosepticum. These regulatory signals control putative transcription units covering about 40% of the P. atrosepticum chromosome. Reviewing the annotation in cases where it didn’t fit with regulatory information allowed us to correct product and gene names for over 300 loci.

  19. Does Introducing more User-friendly Software Produce better Integrated Learning in an Undergraduate Course on Climate Modelling?

    Science.gov (United States)

    Fletcher, C. G.

    2015-12-01

    Appropriate use of technology in the classroom can help to integrate content and process learning; however, there are multiple barriers to introducing technological aids in the classroom that can reduce their effectiveness. In this pilot study we evaluate the impact on student learning from switching to more user-friendly software for lab assignments in an undergraduate course on climate modelling. Computer programming-based labs are replaced by a menu-driven modelling application called EdGCM, developed by Columbia University and the NASA Goddard Institute for Space Studies. The EdGCM tool allows students to explore and visualize a wider array of aspects of climate variability and change—and in greater depth—than was possible previously. The goals of this study are (i) to make the course material more accessible to students regardless of their computing background; and (ii) to improve the level of students' knowledge retention in core climate science concepts. The impact of the change in software is measured using a combination of class surveys and students' test scores. Differences in the level of integration between content and process learning, compared to previous iterations of the course without EdGCM, are discussed.

  20. A Mechanistically Informed User-Friendly Model to Predict Greenhouse Gas (GHG) Fluxes and Carbon Storage from Coastal Wetlands

    Science.gov (United States)

    Abdul-Aziz, O. I.; Ishtiaq, K. S.

    2015-12-01

    We present a user-friendly modeling tool on MS Excel to predict the greenhouse gas (GHG) fluxes and estimate potential carbon sequestration from the coastal wetlands. The dominant controls of wetland GHG fluxes and their relative mechanistic linkages with various hydro-climatic, sea level, biogeochemical and ecological drivers were first determined by employing a systematic data-analytics method, including Pearson correlation matrix, principal component and factor analyses, and exploratory partial least squares regressions. The mechanistic knowledge and understanding was then utilized to develop parsimonious non-linear (power-law) models to predict wetland carbon dioxide (CO2) and methane (CH4) fluxes based on a sub-set of climatic, hydrologic and environmental drivers such as the photosynthetically active radiation, soil temperature, water depth, and soil salinity. The models were tested with field data for multiple sites and seasons (2012-13) collected from the Waquoit Bay, MA. The model estimated the annual wetland carbon storage by up-scaling the instantaneous predicted fluxes to an extended growing season (e.g., May-October) and by accounting for the net annual lateral carbon fluxes between the wetlands and estuary. The Excel Spreadsheet model is a simple ecological engineering tool for coastal carbon management and their incorporation into a potential carbon market under a changing climate, sea level and environment. Specifically, the model can help to determine appropriate GHG offset protocols and monitoring plans for projects that focus on tidal wetland restoration and maintenance.

  1. SigmoID: a user-friendly tool for improving bacterial genome annotation through analysis of transcription control signals.

    Science.gov (United States)

    Nikolaichik, Yevgeny; Damienikan, Aliaksandr U

    2016-01-01

    The majority of bacterial genome annotations are currently automated and based on a 'gene by gene' approach. Regulatory signals and operon structures are rarely taken into account which often results in incomplete and even incorrect gene function assignments. Here we present SigmoID, a cross-platform (OS X, Linux and Windows) open-source application aiming at simplifying the identification of transcription regulatory sites (promoters, transcription factor binding sites and terminators) in bacterial genomes and providing assistance in correcting annotations in accordance with regulatory information. SigmoID combines a user-friendly graphical interface to well known command line tools with a genome browser for visualising regulatory elements in genomic context. Integrated access to online databases with regulatory information (RegPrecise and RegulonDB) and web-based search engines speeds up genome analysis and simplifies correction of genome annotation. We demonstrate some features of SigmoID by constructing a series of regulatory protein binding site profiles for two groups of bacteria: Soft Rot Enterobacteriaceae (Pectobacterium and Dickeya spp.) and Pseudomonas spp. Furthermore, we inferred over 900 transcription factor binding sites and alternative sigma factor promoters in the annotated genome of Pectobacterium atrosepticum. These regulatory signals control putative transcription units covering about 40% of the P. atrosepticum chromosome. Reviewing the annotation in cases where it didn't fit with regulatory information allowed us to correct product and gene names for over 300 loci.

  2. Development and Reliability of a User-Friendly Multicenter Phenotyping Application for Hemorrhagic and Ischemic Stroke.

    Science.gov (United States)

    Owolabi, Mayowa; Ogbole, Godwin; Akinyemi, Rufus; Salaam, Kehinde; Akpa, Onoja; Mongkolwat, Pattanasak; Omisore, Adeleye; Agunloye, Atinuke; Efidi, Richard; Odo, Joseph; Makanjuola, Akintomiwa; Akpalu, Albert; Sarfo, Fred; Owolabi, Lukman; Obiako, Reginald; Wahab, Kolawole; Sanya, Emmanuel; Adebayo, Philip; Komolafe, Morenikeji; Adeoye, Abiodun Moshood; Fawale, Michael B; Akinyemi, Joshua; Osaigbovo, Godwin; Sunmonu, Taofiki; Olowoyo, Paul; Chukwuonye, Innocent; Obiabo, Yahaya; Ibinaiye, Philip; Dambatta, Abdul; Mensah, Yaw; Abdul, Salaam; Olabinri, Eunice; Ikubor, Joyce; Oyinloye, Olalekan; Odunlami, Femi; Melikam, Ezinne; Saulson, Raelle; Kolo, Philip; Ogunniyi, Adesola; Ovbiagele, Bruce

    2017-07-29

    Annotation and Image Markup on ClearCanvas Enriched Stroke-phenotyping Software (ACCESS) is a novel stand-alone computer software application that allows the creation of simple standardized annotations for reporting brain images of all stroke types. We developed the ACCESS application and determined its inter-rater and intra-rater reliability in the Stroke Investigative Research and Educational Network (SIREN) study to assess its suitability for multicenter studies. One hundred randomly selected stroke imaging reports from 5 SIREN sites were re-evaluated by 4 trained independent raters to determine the inter-rater reliability of the ACCESS (version 12.0) software for stroke phenotyping. To determine intra-rater reliability, 6 raters reviewed the same cases previously reported by them after a month of interval. Ischemic stroke was classified using the Oxfordshire Community Stroke Project (OCSP), Trial of Org 10172 in Acute Stroke Treatment (TOAST), and Atherosclerosis, Small-vessel disease, Cardiac source, Other cause (ASCO) protocols, while hemorrhagic stroke was classified using the Structural lesion, Medication, Amyloid angiopathy, Systemic disease, Hypertensive angiopathy and Undetermined (SMASH-U) protocol in ACCESS. Agreement among raters was measured with Cohen's kappa statistics. For primary stroke type, inter-rater agreement was .98 (95% confidence interval [CI], .94-1.00), while intra-rater agreement was 1.00 (95% CI, 1.00). For OCSP subtypes, inter-rater agreement was .97 (95% CI, .92-1.00) for the partial anterior circulation infarcts, .92 (95% CI, .76-1.00) for the total anterior circulation infarcts, and excellent for both lacunar infarcts and posterior circulation infarcts. Intra-rater agreement was .97 (.90-1.00), while inter-rater agreement was .93 (95% CI, .84-1.00) for TOAST subtypes. Inter-rater agreement ranged between .78 (cardioembolic) and .91 (large artery atherosclerotic) for ASCO subtypes and was .80 (95% CI, .56-1.00) for SMASH-U subtypes

  3. Enhanced UWB Radio Channel Model for Short-Range Communication Scenarios Including User Dynamics

    DEFF Research Database (Denmark)

    Kovacs, Istvan Zsolt; Nguyen, Tuan Hung; Eggers, Patrick Claus F.

    2005-01-01

    In this paper we propose a SISO UWB radio channel model for short-range radio link scenarios between a fixed device and a dynamic user hand-held device. The channel model is derived based on novel experimental UWB radio propagation investigations carried out in typical indoor PAN scenarios...... including realistic device and user terminal antenna configurations. The radio channel measurements have been performed in the lower UWB frequency band of 3GHz to 5GHz with a 2x4 MIMO antenna configuration. Several environments, user scenarios and two types of user terminals have been used. The developed...

  4. User friendly packaging

    DEFF Research Database (Denmark)

    Geert Jensen, Birgitte

    2010-01-01

    Most consumers have experienced occasional problems with opening packaging. Tomato sauce from the tinned mackerel splattered all over the kitchen counter, the unrelenting pickle jar lid, and the package of sliced ham that cannot be opened without a knife or a pair of scissors. The research project...

  5. User friendly joystick

    Science.gov (United States)

    Eklund, Wayne D. (Inventor); Kerley, James J. (Inventor)

    1992-01-01

    A joystick control device having a lower U-shaped bracket, an upper U-shaped bracket, a handle attached to the upper U-shaped bracket, with the upper U-shaped bracket connected to the lower U-shaped bracket by a compliant joint allowing six degrees of freedom for the joystick. The compliant joint consists of at least one cable segment affixed between the lower U-shaped bracket and the upper U-shaped bracket. At least one input device is located between the lower U-shaped bracket and the upper U-shaped bracket.

  6. Biblio-MetReS for user-friendly mining of genes and biological processes in scientific documents

    Directory of Open Access Journals (Sweden)

    Anabel Usie

    2014-02-01

    Full Text Available One way to initiate the reconstruction of molecular circuits is by using automated text-mining techniques. Developing more efficient methods for such reconstruction is a topic of active research, and those methods are typically included by bioinformaticians in pipelines used to mine and curate large literature datasets. Nevertheless, experimental biologists have a limited number of available user-friendly tools that use text-mining for network reconstruction and require no programming skills to use. One of these tools is Biblio-MetReS. Originally, this tool permitted an on-the-fly analysis of documents contained in a number of web-based literature databases to identify co-occurrence of proteins/genes. This approach ensured results that were always up-to-date with the latest live version of the databases. However, this ‘up-to-dateness’ came at the cost of large execution times. Here we report an evolution of the application Biblio-MetReS that permits constructing co-occurrence networks for genes, GO processes, Pathways, or any combination of the three types of entities and graphically represent those entities. We show that the performance of Biblio-MetReS in identifying gene co-occurrence is as least as good as that of other comparable applications (STRING and iHOP. In addition, we also show that the identification of GO processes is on par to that reported in the latest BioCreAtIvE challenge. Finally, we also report the implementation of a new strategy that combines on-the-fly analysis of new documents with preprocessed information from documents that were encountered in previous analyses. This combination simultaneously decreases program run time and maintains ‘up-to-dateness’ of the results. Availability: http://metres.udl.cat/index.php/downloads, Contact: metres.cmb@gmail.com.

  7. Vestibular rehabilitation using the Nintendo® Wii Balance Board -- a user-friendly alternative for central nervous compensation.

    Science.gov (United States)

    Sparrer, Ingo; Duong Dinh, Thien An; Ilgner, Justus; Westhofen, Martin

    2013-03-01

    The Nintendo® Wii Balance Board is a cost-effective and user-friendly alternative to other popular frequently used systems that aid vestibular compensation, particularly in elderly patients. In addition, further treatment in the home environment is possible. This cohort study was designed to investigate the impact of the Nintendo® Wii Balance Board as a visual compensation device after acute vestibular neuritis. Subjects were randomly assigned to one of two treatment groups. Group A (n = 37) performed customized exercises with the Nintendo® Wii Balance Board. Group B (n = 34) performed only two elected exercises as a control group for comparison of the results. Both groups underwent additive therapy with steroids (intravenous) in decreasing doses (250 mg decreasing to 25 mg over 10 days). The Sensory Organization Test (SOT), Dizziness Handicap Inventory (DHI), Vertigo Symptom Scale (VSS), and Tinneti questionnaire were evaluated immediately before treatment (baseline), at the end of treatment, i.e. at day 5, and after 10 weeks. The early use of a visual feedback system in the context of the balance training supports the central nervous vestibular compensation after peripheral labyrinthine disorders. Patients in group B (without training) required a longer in-patient stay (average 2.4 days, SD 0.4) compared with patients following early Wii rehabilitation. The absence of nystagmus under Frenzel's goggles in group A was observed 2.1 days (SD 0.5) earlier than in group B. Group A showed significantly better results in the SOT, DHI, VSS, and Tinneti questionnaire at all time points measured (p < 0.05).

  8. The Effect of User-Friendly Texts vs. Impersonal and Hybrid Texts on the Reading Comprehension Ability of Iranian EFL Learners

    Directory of Open Access Journals (Sweden)

    Esmail Faghih

    2008-05-01

    Full Text Available This study focuses on the effect of user-friendly, impersonal, and hybrid texts on the reading comprehension ability of Iranian foreign language learners. Forty-five students of AlzahraUniversity were selected on the basis of their performance in a recent TOEFL. They were given three different texts (each group of 15 students was given one type describing the same area of English usage, which were all followed by a reading comprehension test. Also, a questionnaire containing two questions was given to the participants in order to tap their own personal feelings. Series of one-way ANOVA displayed that the mean differences among the three groups were significant at 0.05 level and the user-friendly group outperformed the other ones.

  9. 人性化软件界面设计的历史和原则%The History and Principles of the User-friendly Software UI Design

    Institute of Scientific and Technical Information of China (English)

    张萍

    2011-01-01

    从软件编码以及软件界面设计的发展历史入手,详述了软件界面的3种历史形态,即批处理界面、命令行用户界面、图形用户界面,指出软件界面设计应以人为本,人性化是软件界面设计的本质要求。在此基础上,进一步分析了人性化设计在软件界面的色彩、布局、交互性3个方面的应用原则,指出配色应种类适中、形象独特、色调统一、符合用户心理特征;布局应遵循简洁、顺序、规范、平衡和对比等原则;而交互性中换肤以及智能布局是人性化软件界面设计的2个重要发展方向。%From the development history of the software coding and UI (User Interface) design, three historical forms of software UI, i.e. batch interface, command line user interface and graphical user interface were described in detail. A viewpoint that the software UI design should be human-oriented and the user-friendly design being its essential requirement was proposed. On this basis, further discussion on the principles of user-friendly principle in software UI design were taken in three respects of color, layout and interactivity. And it pointed out that the color applied in software UI should be moderate, unique, uniform and coincident with the psychological characteristics of users. These principles of simplicity, sequence, normalization, balance and contrast should be followed in its layout and the skin replacement and intelligent layout in terms of the interactivity were two important development directions of user-friendly software UI design.

  10. People...Serving People; A 1977 Long-Range User Program for Nebraska Libraries.

    Science.gov (United States)

    Nebraska Library Commission, Lincoln.

    In order to design an effective long-range program for human beings, a planner must face the realization that: (1) library users are the only valid sources for evaluating services; (2) empathy for those whom the library intends to serve must be the primary concern; and (3) stated criteria for evaluating library service must be in measurable terms.…

  11. A preliminary user-friendly, digital console for the control room parameters supervision in old-generation Nuclear Plants

    Energy Technology Data Exchange (ETDEWEB)

    Memmi, F.; Falconi, L.; Cappelli, M.; Palomba, M.; Santoro, E.; Bove, R.; Sepielli, M. [UTFISST, ENEA Casaccia, via Anguillarese 301, Rome (Italy)

    2012-07-01

    aim of this work is the possibility to have a front panel available on a web interface: CompactRio acts as a remote server and it is accessible on a dedicated LAN. This supervisory system has been tested and validated on the basis of the real control console for the 1-MW TRIGA reactor RC-1 at the ENEA, Casaccia Research Center. In this paper we show some results obtained by recording each variable as the reactor reaches its maximum level of power. The choice of a research reactor for testing the developed system relies on its training and didactic importance for the education of plant operators: in this context a digital instrument can offer a better user-friendly tool for learning and training. It is worthwhile to remark that such a system does not interfere with the console instrumentation, the latter continuing to preserve the total control. (authors)

  12. Retention payoff-based cost per day open regression equations: Application in a user-friendly decision support tool for investment analysis of automated estrus detection technologies.

    Science.gov (United States)

    Dolecheck, K A; Heersche, G; Bewley, J M

    2016-12-01

    Assessing the economic implications of investing in automated estrus detection (AED) technologies can be overwhelming for dairy producers. The objectives of this study were to develop new regression equations for estimating the cost per day open (DO) and to apply the results to create a user-friendly, partial budget, decision support tool for investment analysis of AED technologies. In the resulting decision support tool, the end user can adjust herd-specific inputs regarding general management, current reproductive management strategies, and the proposed AED system. Outputs include expected DO, reproductive cull rate, net present value, and payback period for the proposed AED system. Utility of the decision support tool was demonstrated with an example dairy herd created using data from DairyMetrics (Dairy Records Management Systems, Raleigh, NC), Food and Agricultural Policy Research Institute (Columbia, MO), and published literature. Resulting herd size, rolling herd average milk production, milk price, and feed cost were 323 cows, 10,758kg, $0.41/kg, and $0.20/kg of dry matter, respectively. Automated estrus detection technologies with 2 levels of initial system cost (low: $5,000 vs. high: $10,000), tag price (low: $50 vs. high: $100), and estrus detection rate (low: 60% vs. high: 80%) were compared over a 7-yr investment period. Four scenarios were considered in a demonstration of the investment analysis tool: (1) a herd using 100% visual observation for estrus detection before adopting 100% AED, (2) a herd using 100% visual observation before adopting 75% AED and 25% visual observation, (3) a herd using 100% timed artificial insemination (TAI) before adopting 100% AED, and (4) a herd using 100% TAI before adopting 75% AED and 25% TAI. Net present value in scenarios 1 and 2 was always positive, indicating a positive investment situation. Net present value in scenarios 3 and 4 was always positive in combinations using a $50 tag price, and in scenario 4, the $5

  13. A user-friendly means to scale from the biochemistry of photosynthesis to whole crop canopies and production in time and space - development of Java WIMOVAC.

    Science.gov (United States)

    Song, Qingfeng; Chen, Dairui; Long, Stephen P; Zhu, Xin-Guang

    2017-01-01

    Windows Intuitive Model of Vegetation response to Atmosphere and Climate Change (WIMOVAC) has been used widely as a generic modular mechanistically rich model of plant production. It can predict the responses of leaf and canopy carbon balance, as well as production in different environmental conditions, in particular those relevant to global change. Here, we introduce an open source Java user-friendly version of WIMOVAC. This software is platform independent and can be easily downloaded to a laptop and used without any prior programming skills. In this article, we describe the structure, equations and user guide and illustrate some potential applications of WIMOVAC. © 2016 The Authors Plant, Cell & Environment Published by John Wiley & Sons Ltd.

  14. A user-friendly, dynamic web environment for remote data browsing and analysis of multiparametric geophysical data within the MULTIMO project

    Science.gov (United States)

    Carniel, Roberto; Di Cecca, Mauro; Jaquet, Olivier

    2006-05-01

    In the framework of the EU-funded project "Multi-disciplinary monitoring, modelling and forecasting of volcanic hazard" (MULTIMO), multiparametric data have been recorded at the MULTIMO station in Montserrat. Moreover, several other long time series, recorded at Montserrat and at other volcanoes, have been acquired in order to test stochastic and deterministic methodologies under development. Creating a general framework to handle data efficiently is a considerable task even for homogeneous data. In the case of heterogeneous data, this becomes a major issue. A need for a consistent way of browsing such a heterogeneous dataset in a user-friendly way therefore arose. Additionally, a framework for applying the calculation of the developed dynamical parameters on the data series was also needed in order to easily keep these parameters under control, e.g. for monitoring, research or forecasting purposes. The solution which we present is completely based on Open Source software, including Linux operating system, MySql database management system, Apache web server, Zope application server, Scilab math engine, Plone content management framework, Unified Modelling Language. From the user point of view the main advantage is the possibility of browsing through datasets recorded on different volcanoes, with different instruments, with different sampling frequencies, stored in different formats, all via a consistent, user- friendly interface that transparently runs queries to the database, gets the data from the main storage units, generates the graphs and produces dynamically generated web pages to interact with the user. The involvement of third parties for continuing the development in the Open Source philosophy and/or extending the application fields is now sought.

  15. CloudDOE: a user-friendly tool for deploying Hadoop clouds and analyzing high-throughput sequencing data with MapReduce.

    Science.gov (United States)

    Chung, Wei-Chun; Chen, Chien-Chih; Ho, Jan-Ming; Lin, Chung-Yen; Hsu, Wen-Lian; Wang, Yu-Chun; Lee, D T; Lai, Feipei; Huang, Chih-Wei; Chang, Yu-Jung

    2014-01-01

    Explosive growth of next-generation sequencing data has resulted in ultra-large-scale data sets and ensuing computational problems. Cloud computing provides an on-demand and scalable environment for large-scale data analysis. Using a MapReduce framework, data and workload can be distributed via a network to computers in the cloud to substantially reduce computational latency. Hadoop/MapReduce has been successfully adopted in bioinformatics for genome assembly, mapping reads to genomes, and finding single nucleotide polymorphisms. Major cloud providers offer Hadoop cloud services to their users. However, it remains technically challenging to deploy a Hadoop cloud for those who prefer to run MapReduce programs in a cluster without built-in Hadoop/MapReduce. We present CloudDOE, a platform-independent software package implemented in Java. CloudDOE encapsulates technical details behind a user-friendly graphical interface, thus liberating scientists from having to perform complicated operational procedures. Users are guided through the user interface to deploy a Hadoop cloud within in-house computing environments and to run applications specifically targeted for bioinformatics, including CloudBurst, CloudBrush, and CloudRS. One may also use CloudDOE on top of a public cloud. CloudDOE consists of three wizards, i.e., Deploy, Operate, and Extend wizards. Deploy wizard is designed to aid the system administrator to deploy a Hadoop cloud. It installs Java runtime environment version 1.6 and Hadoop version 0.20.203, and initiates the service automatically. Operate wizard allows the user to run a MapReduce application on the dashboard list. To extend the dashboard list, the administrator may install a new MapReduce application using Extend wizard. CloudDOE is a user-friendly tool for deploying a Hadoop cloud. Its smart wizards substantially reduce the complexity and costs of deployment, execution, enhancement, and management. Interested users may collaborate to improve the

  16. CloudDOE: a user-friendly tool for deploying Hadoop clouds and analyzing high-throughput sequencing data with MapReduce.

    Directory of Open Access Journals (Sweden)

    Wei-Chun Chung

    Full Text Available BACKGROUND: Explosive growth of next-generation sequencing data has resulted in ultra-large-scale data sets and ensuing computational problems. Cloud computing provides an on-demand and scalable environment for large-scale data analysis. Using a MapReduce framework, data and workload can be distributed via a network to computers in the cloud to substantially reduce computational latency. Hadoop/MapReduce has been successfully adopted in bioinformatics for genome assembly, mapping reads to genomes, and finding single nucleotide polymorphisms. Major cloud providers offer Hadoop cloud services to their users. However, it remains technically challenging to deploy a Hadoop cloud for those who prefer to run MapReduce programs in a cluster without built-in Hadoop/MapReduce. RESULTS: We present CloudDOE, a platform-independent software package implemented in Java. CloudDOE encapsulates technical details behind a user-friendly graphical interface, thus liberating scientists from having to perform complicated operational procedures. Users are guided through the user interface to deploy a Hadoop cloud within in-house computing environments and to run applications specifically targeted for bioinformatics, including CloudBurst, CloudBrush, and CloudRS. One may also use CloudDOE on top of a public cloud. CloudDOE consists of three wizards, i.e., Deploy, Operate, and Extend wizards. Deploy wizard is designed to aid the system administrator to deploy a Hadoop cloud. It installs Java runtime environment version 1.6 and Hadoop version 0.20.203, and initiates the service automatically. Operate wizard allows the user to run a MapReduce application on the dashboard list. To extend the dashboard list, the administrator may install a new MapReduce application using Extend wizard. CONCLUSIONS: CloudDOE is a user-friendly tool for deploying a Hadoop cloud. Its smart wizards substantially reduce the complexity and costs of deployment, execution, enhancement, and

  17. New user-friendly approach to obtain an Eisenberg plot and its use as a practical tool in protein sequence analysis.

    Science.gov (United States)

    Keller, Rob C A

    2011-01-01

    The Eisenberg plot or hydrophobic moment plot methodology is one of the most frequently used methods of bioinformatics. Bioinformatics is more and more recognized as a helpful tool in Life Sciences in general, and recent developments in approaches recognizing lipid binding regions in proteins are promising in this respect. In this study a bioinformatics approach specialized in identifying lipid binding helical regions in proteins was used to obtain an Eisenberg plot. The validity of the Heliquest generated hydrophobic moment plot was checked and exemplified. This study indicates that the Eisenberg plot methodology can be transferred to another hydrophobicity scale and renders a user-friendly approach which can be utilized in routine checks in protein-lipid interaction and in protein and peptide lipid binding characterization studies. A combined approach seems to be advantageous and results in a powerful tool in the search of helical lipid-binding regions in proteins and peptides. The strength and limitations of the Eisenberg plot approach itself are discussed as well. The presented approach not only leads to a better understanding of the nature of the protein-lipid interactions but also provides a user-friendly tool for the search of lipid-binding regions in proteins and peptides.

  18. Siberian Earth System Science Cluster - A web-based Geoportal to provide user-friendly Earth Observation Products for supporting NEESPI scientists

    Science.gov (United States)

    Eberle, J.; Gerlach, R.; Hese, S.; Schmullius, C.

    2012-04-01

    To provide earth observation products in the area of Siberia, the Siberian Earth System Science Cluster (SIB-ESS-C) was established as a spatial data infrastructure at the University of Jena (Germany), Department for Earth Observation. This spatial data infrastructure implements standards published by the Open Geospatial Consortium (OGC) and the International Organizsation for Standardization (ISO) for data discovery, data access, data processing and data analysis. The objective of SIB-ESS-C is to faciliate environmental research and Earth system science in Siberia. The region for this project covers the entire Asian part of the Russian Federation approximately between 58°E - 170°W and 48°N - 80°N. To provide discovery, access and analysis services a webportal was published for searching and visualisation of available data. This webportal is based on current web technologies like AJAX, Drupal Content Management System as backend software and a user-friendly surface with Drag-n-Drop and further mouse events. To have a wide range of regular updated earth observation products, some products from sensor MODIS at the satellites Aqua and Terra were processed. A direct connection to NASA archive servers makes it possible to download MODIS Level 3 and 4 products and integrate it in the SIB-ESS-C infrastructure. These data can be downloaded in a file format called Hierarchical Data Format (HDF). For visualisation and further analysis, this data is reprojected, converted to GeoTIFF and global products clipped to the project area. All these steps are implemented as an automatic process chain. If new MODIS data is available within the infrastructure this process chain is executed. With the link to a MODIS catalogue system, the system gets new data daily. With the implemented analysis processes, timeseries data can be analysed, for example to plot a trend or different time series against one another. Scientists working in this area and working with MODIS data can make use

  19. A user-friendly Matlab program and GUI for the pseudorotation analysis of saturated five-membered ring systems based on scalar coupling constants

    Directory of Open Access Journals (Sweden)

    Martins José C

    2008-10-01

    Full Text Available Abstract Background The advent of combinatorial chemistry has revived the interest in five-membered heterocyclic rings as scaffolds in pharmaceutical research. They are also the target of modifications in nucleic acid chemistry. Hence, the characterization of their conformational features is of considerable interest. This can be accomplished from the analysis of the 3JHH scalar coupling constants. Results A freely available program including an easy-to-use graphical user interface (GUI has been developed for the calculation of five-membered ring conformations from scalar coupling constant data. A variety of operational modes and parameterizations can be selected by the user, and the coupling constants and electronegativity parameters can be defined interactively. Furthermore, the possibility of generating high-quality graphical output of the conformational space accessible to the molecule under study facilitates the interpretation of the results. These features are illustrated via the conformational analysis of two 4'-thio-2'-deoxynucleoside analogs. Results are discussed and compared with those obtained using the original PSEUROT program. Conclusion A user-friendly Matlab interface has been developed and tested. This should considerably improve the accessibility of this kind of calculations to the chemical community.

  20. A User Differential Range Error Calculating Algorithm Based on Analytic Method

    Institute of Scientific and Technical Information of China (English)

    SHAO Bo; LIU Jiansheng; ZHAO Ruibin; HUANG Zhigang; LI Rui

    2011-01-01

    To enhance the integrity,an analytic method (AM) which has less execution time is proposed to calculate the user differential range error (UDRE) used by the user to detect the potential risk.An ephemeris and clock correction calculation method is introduced first.It shows that the most important thing of computing UDRE is to find the worst user location (WUL) in the service volume.Then,a UDRE algorithm using AM is described to solve this problem.By using the covariance matrix of the error vector,the searching of WUL is converted to an analytic geometry problem.The location of WUL can be obtained directly by mathematical derivation.Experiments are conducted to compare the performance between the proposed AM algorithm and the exhaustive grid search (EGS) method used in the master station.The results show that the correctness of the AM algorithm can be proved by the EGS method and the AM algorithm can reduce the calculation time by more than 90%.The computational complexity of this proposed algorithm is better than that of EGS.Thereby this algorithm is more suitable for computing UDRE at the master station.

  1. Individual-Based Modeling of Tuberculosis in a User-Friendly Interface: Understanding the Epidemiological Role of Population Heterogeneity in a City.

    Science.gov (United States)

    Prats, Clara; Montañola-Sales, Cristina; Gilabert-Navarro, Joan F; Valls, Joaquim; Casanovas-Garcia, Josep; Vilaplana, Cristina; Cardona, Pere-Joan; López, Daniel

    2015-01-01

    For millennia tuberculosis (TB) has shown a successful strategy to survive, making it one of the world's deadliest infectious diseases. This resilient behavior is based not only on remaining hidden in most of the infected population, but also by showing slow evolution in most sick people. The course of the disease within a population is highly related to its heterogeneity. Thus, classic epidemiological approaches with a top-down perspective have not succeeded in understanding its dynamics. In the past decade a few individual-based models were built, but most of them preserved a top-down view that makes it difficult to study a heterogeneous population. We propose an individual-based model developed with a bottom-up approach to studying the dynamics of pulmonary TB in a certain population, considered constant. Individuals may belong to the following classes: healthy, infected, sick, under treatment, and treated with a probability of relapse. Several variables and parameters account for their age, origin (native or immigrant), immunodeficiency, diabetes, and other risk factors (smoking and alcoholism). The time within each infection state is controlled, and sick individuals may show a cavitated disease or not that conditions infectiousness. It was implemented in NetLogo because it allows non-modelers to perform virtual experiments with a user-friendly interface. The simulation was conducted with data from Ciutat Vella, a district of Barcelona with an incidence of 67 TB cases per 100,000 inhabitants in 2013. Several virtual experiments were performed to relate the disease dynamics with the structure of the infected subpopulation (e.g., the distribution of infected times). Moreover, the short-term effect of health control policies on modifying that structure was studied. Results show that the characteristics of the population are crucial for the local epidemiology of TB. The developed user-friendly tool is ready to test control strategies of disease in any city in the

  2. Individual-based modeling of tuberculosis in a user-friendly interface: understanding the epidemiological role of population heterogeneity in a city

    Directory of Open Access Journals (Sweden)

    Clara ePrats

    2016-01-01

    Full Text Available For millennia tuberculosis has shown a successful strategy to survive, making it one of the world’s deadliest infectious diseases. This resilient behavior is based not only on remaining hidden in most of the infected population, but also by showing slow evolution in most sick people. The course of the disease within a population is highly related to its heterogeneity. Thus, classic epidemiological approaches with a top-down perspective have not succeeded in understanding its dynamics. In the past decade a few individual-based models were built, but most of them preserved a top-down view that makes it difficult to study a heterogeneous population.We propose an individual-based model developed with a bottom-up approach to studying the dynamics of pulmonary tuberculosis in a certain population, considered constant. Individuals may belong to the following classes: healthy, infected, sick, under treatment, and treated with a probability of relapse. Several variables and parameters account for their age, origin (native or immigrant, immunodeficiency, diabetes, and other risk factors (smoking and alcoholism. The time within each infection state is controlled, and sick individuals may show a cavitated disease or not that conditions infectiousness. It was implemented in NetLogo because it allows non-modelers to perform virtual experiments with a user-friendly interface.The simulation was conducted with data from Ciutat Vella, a district of Barcelona with an incidence of 67 tuberculosis cases per 100,000 inhabitants in 2013. Several virtual experiments were performed to relate the disease dynamics with the structure of the infected subpopulation (e.g., the distribution of infected times. Moreover, the short-term effect of health control policies on modifying that structure was studied. Results show that the characteristics of the population are crucial for the local epidemiology of tuberculosis. The developed user-friendly tool is ready to test control

  3. Development of a user-friendly system for image processing of electron microscopy by integrating a web browser and PIONE with Eos.

    Science.gov (United States)

    Tsukamoto, Takafumi; Yasunaga, Takuo

    2014-11-01

    Eos (Extensible object-oriented system) is one of the powerful applications for image processing of electron micrographs. In usual cases, Eos works with only character user interfaces (CUI) under the operating systems (OS) such as OS-X or Linux, not user-friendly. Thus, users of Eos need to be expert at image processing of electron micrographs, and have a little knowledge of computer science, as well. However, all the persons who require Eos does not an expert for CUI. Thus we extended Eos to a web system independent of OS with graphical user interfaces (GUI) by integrating web browser.Advantage to use web browser is not only to extend Eos with GUI, but also extend Eos to work under distributed computational environment. Using Ajax (Asynchronous JavaScript and XML) technology, we implemented more comfortable user-interface on web browser. Eos has more than 400 commands related to image processing for electron microscopy, and the usage of each command is different from each other. Since the beginning of development, Eos has managed their user-interface by using the interface definition file of "OptionControlFile" written in CSV (Comma-Separated Value) format, i.e., Each command has "OptionControlFile", which notes information for interface and its usage generation. Developed GUI system called "Zephyr" (Zone for Easy Processing of HYpermedia Resources) also accessed "OptionControlFIle" and produced a web user-interface automatically, because its mechanism is mature and convenient,The basic actions of client side system was implemented properly and can supply auto-generation of web-form, which has functions of execution, image preview, file-uploading to a web server. Thus the system can execute Eos commands with unique options for each commands, and process image analysis. There remain problems of image file format for visualization and workspace for analysis: The image file format information is useful to check whether the input/output file is correct and we also

  4. Developing a useful, user-friendly website for cancer patient follow-up: users' perspectives on ease of access and usefulness.

    Science.gov (United States)

    Bartlett, Y K; Selby, D L; Newsham, A; Keding, A; Forman, D; Brown, J; Velikova, G; Wright, P

    2012-11-01

    UK cancer survival has improved, leading to an increase in review patients and pressure on clinics. Use of the Internet for information exchange between patients and healthcare staff may provide a useful adjunct or alternative to traditional follow-up. This study aimed to develop and evaluate a website for use in follow-up cancer care in terms of usability, feasibility and acceptability. A website was developed and underwent iterative amendment following patient usability testing in focus groups. Patients on follow-up completed a Computer and Internet Usage Questionnaire. Internet users consented to a randomised crossover study to complete paper and online questionnaires, browse the website and participate in a website evaluation interview. Patient website use was tracked. Usability: Website changes were made following patient testing (n= 21). Patients would have liked a 'personalized' website with links to their clinical team, out with the scope of this study. Feasibility: The majority of participants (65%) had Internet access. Age remained a differentiating factor. Acceptability: Final evaluation (n= 103) was positive although many would like to maintain face-to-face hospital contact. User involvement in website design can ensure patient needs are met. A website model for follow-up will suit some patients but others will prefer clinical contact.

  5. CORE_TF: a user-friendly interface to identify evolutionary conserved transcription factor binding sites in sets of co-regulated genes

    Science.gov (United States)

    Hestand, Matthew S; van Galen, Michiel; Villerius, Michel P; van Ommen, Gert-Jan B; den Dunnen, Johan T; 't Hoen, Peter AC

    2008-01-01

    Background The identification of transcription factor binding sites is difficult since they are only a small number of nucleotides in size, resulting in large numbers of false positives and false negatives in current approaches. Computational methods to reduce false positives are to look for over-representation of transcription factor binding sites in a set of similarly regulated promoters or to look for conservation in orthologous promoter alignments. Results We have developed a novel tool, "CORE_TF" (Conserved and Over-REpresented Transcription Factor binding sites) that identifies common transcription factor binding sites in promoters of co-regulated genes. To improve upon existing binding site predictions, the tool searches for position weight matrices from the TRANSFACR database that are over-represented in an experimental set compared to a random set of promoters and identifies cross-species conservation of the predicted transcription factor binding sites. The algorithm has been evaluated with expression and chromatin-immunoprecipitation on microarray data. We also implement and demonstrate the importance of matching the random set of promoters to the experimental promoters by GC content, which is a unique feature of our tool. Conclusion The program CORE_TF is accessible in a user friendly web interface at . It provides a table of over-represented transcription factor binding sites in the users input genes' promoters and a graphical view of evolutionary conserved transcription factor binding sites. In our test data sets it successfully predicts target transcription factors and their binding sites. PMID:19036135

  6. A user-friendly mathematical modelling web interface to assist local decision making in the fight against drug-resistant tuberculosis.

    Science.gov (United States)

    Ragonnet, Romain; Trauer, James M; Denholm, Justin T; Marais, Ben J; McBryde, Emma S

    2017-05-30

    Multidrug-resistant and rifampicin-resistant tuberculosis (MDR/RR-TB) represent an important challenge for global tuberculosis (TB) control. The high rates of MDR/RR-TB observed among re-treatment cases can arise from diverse pathways: de novo amplification during initial treatment, inappropriate treatment of undiagnosed MDR/RR-TB, relapse despite appropriate treatment, or reinfection with MDR/RR-TB. Mathematical modelling allows quantification of the contribution made by these pathways in different settings. This information provides valuable insights for TB policy-makers, allowing better contextualised solutions. However, mathematical modelling outputs need to consider local data and be easily accessible to decision makers in order to improve their usefulness. We present a user-friendly web-based modelling interface, which can be used by people without technical knowledge. Users can input their own parameter values and produce estimates for their specific setting. This innovative tool provides easy access to mathematical modelling outputs that are highly relevant to national TB control programs. In future, the same approach could be applied to a variety of modelling applications, enhancing local decision making.

  7. A user-friendly tool to transform large scale administrative data into wide table format using a mapreduce program with a pig latin based script

    Directory of Open Access Journals (Sweden)

    Horiguchi Hiromasa

    2012-12-01

    Full Text Available Abstract Background Secondary use of large scale administrative data is increasingly popular in health services and clinical research, where a user-friendly tool for data management is in great demand. MapReduce technology such as Hadoop is a promising tool for this purpose, though its use has been limited by the lack of user-friendly functions for transforming large scale data into wide table format, where each subject is represented by one row, for use in health services and clinical research. Since the original specification of Pig provides very few functions for column field management, we have developed a novel system called GroupFilterFormat to handle the definition of field and data content based on a Pig Latin script. We have also developed, as an open-source project, several user-defined functions to transform the table format using GroupFilterFormat and to deal with processing that considers date conditions. Results Having prepared dummy discharge summary data for 2.3 million inpatients and medical activity log data for 950 million events, we used the Elastic Compute Cloud environment provided by Amazon Inc. to execute processing speed and scaling benchmarks. In the speed benchmark test, the response time was significantly reduced and a linear relationship was observed between the quantity of data and processing time in both a small and a very large dataset. The scaling benchmark test showed clear scalability. In our system, doubling the number of nodes resulted in a 47% decrease in processing time. Conclusions Our newly developed system is widely accessible as an open resource. This system is very simple and easy to use for researchers who are accustomed to using declarative command syntax for commercial statistical software and Structured Query Language. Although our system needs further sophistication to allow more flexibility in scripts and to improve efficiency in data processing, it shows promise in facilitating the application

  8. A user-friendly tool to transform large scale administrative data into wide table format using a MapReduce program with a Pig Latin based script.

    Science.gov (United States)

    Horiguchi, Hiromasa; Yasunaga, Hideo; Hashimoto, Hideki; Ohe, Kazuhiko

    2012-12-22

    Secondary use of large scale administrative data is increasingly popular in health services and clinical research, where a user-friendly tool for data management is in great demand. MapReduce technology such as Hadoop is a promising tool for this purpose, though its use has been limited by the lack of user-friendly functions for transforming large scale data into wide table format, where each subject is represented by one row, for use in health services and clinical research. Since the original specification of Pig provides very few functions for column field management, we have developed a novel system called GroupFilterFormat to handle the definition of field and data content based on a Pig Latin script. We have also developed, as an open-source project, several user-defined functions to transform the table format using GroupFilterFormat and to deal with processing that considers date conditions. Having prepared dummy discharge summary data for 2.3 million inpatients and medical activity log data for 950 million events, we used the Elastic Compute Cloud environment provided by Amazon Inc. to execute processing speed and scaling benchmarks. In the speed benchmark test, the response time was significantly reduced and a linear relationship was observed between the quantity of data and processing time in both a small and a very large dataset. The scaling benchmark test showed clear scalability. In our system, doubling the number of nodes resulted in a 47% decrease in processing time. Our newly developed system is widely accessible as an open resource. This system is very simple and easy to use for researchers who are accustomed to using declarative command syntax for commercial statistical software and Structured Query Language. Although our system needs further sophistication to allow more flexibility in scripts and to improve efficiency in data processing, it shows promise in facilitating the application of MapReduce technology to efficient data processing with

  9. FishPathogens.eu/vhsv: a user-friendly viral haemorrhagic septicaemia virus isolate and sequence database.

    Science.gov (United States)

    Jonstrup, S P; Gray, T; Kahns, S; Skall, H F; Snow, M; Olesen, N J

    2009-11-01

    A database has been created, http://www.FishPathogens.eu, with the aim of providing a single repository for collating important information on significant pathogens of aquaculture, relevant to their control and management. This database will be developed, maintained and managed as part of the European Community Reference Laboratory for Fish Diseases function. This concept has been initially developed for viral haemorrhagic septicaemia virus and will be extended in future to include information on other significant aquaculture pathogens. Information included for each isolate comprises sequence, geographical origin, host origin and useful key literature. Various search mechanisms make it easy to find specific groups of isolates. Search results can be presented in several different ways including table-based, map-based and graph-based outputs. When retrieving sequences, the user is given freedom to obtain data from any selected part of the genome of interest. The output of the sequence search can be readily retrieved as a FASTA file ready to be imported into a sequence alignment tool of choice, facilitating further molecular epidemiological study.

  10. 网络数据库用户界面的使用便利性研究%Study on User-friendly Interfaces of Web-based Databases

    Institute of Scientific and Technical Information of China (English)

    桂君; 郭依群

    2001-01-01

    Based on a comparative study of Cambridge Scientific Abstracts' Internet Database Service and OCLC's FirstSearch, this paper discusses the user-friendly interfaces of Web-based databases according to their characteristics such as database selection, search strategy formulation and reformulation, online help and result output.

  11. CORE_TF: a user-friendly interface to identify evolutionary conserved transcription factor binding sites in sets of co-regulated genes

    Directory of Open Access Journals (Sweden)

    den Dunnen Johan T

    2008-11-01

    Full Text Available Abstract Background The identification of transcription factor binding sites is difficult since they are only a small number of nucleotides in size, resulting in large numbers of false positives and false negatives in current approaches. Computational methods to reduce false positives are to look for over-representation of transcription factor binding sites in a set of similarly regulated promoters or to look for conservation in orthologous promoter alignments. Results We have developed a novel tool, "CORE_TF" (Conserved and Over-REpresented Transcription Factor binding sites that identifies common transcription factor binding sites in promoters of co-regulated genes. To improve upon existing binding site predictions, the tool searches for position weight matrices from the TRANSFACR database that are over-represented in an experimental set compared to a random set of promoters and identifies cross-species conservation of the predicted transcription factor binding sites. The algorithm has been evaluated with expression and chromatin-immunoprecipitation on microarray data. We also implement and demonstrate the importance of matching the random set of promoters to the experimental promoters by GC content, which is a unique feature of our tool. Conclusion The program CORE_TF is accessible in a user friendly web interface at http://www.LGTC.nl/CORE_TF. It provides a table of over-represented transcription factor binding sites in the users input genes' promoters and a graphical view of evolutionary conserved transcription factor binding sites. In our test data sets it successfully predicts target transcription factors and their binding sites.

  12. CO2calc: A User-Friendly Seawater Carbon Calculator for Windows, Mac OS X, and iOS (iPhone)

    Science.gov (United States)

    Robbins, L.L.; Hansen, M.E.; Kleypas, J.A.; Meylan, S.C.

    2010-01-01

    A user-friendly, stand-alone application for the calculation of carbonate system parameters was developed by the U.S. Geological Survey Florida Shelf Ecosystems Response to Climate Change Project in response to its Ocean Acidification Task. The application, by Mark Hansen and Lisa Robbins, USGS St. Petersburg, FL, Joanie Kleypas, NCAR, Boulder, CO, and Stephan Meylan, Jacobs Technology, St. Petersburg, FL, is intended as a follow-on to CO2SYS, originally developed by Lewis and Wallace (1998) and later modified for Microsoft Excel? by Denis Pierrot (Pierrot and others, 2006). Besides eliminating the need for using Microsoft Excel on the host system, CO2calc offers several improvements on CO2SYS, including: An improved graphical user interface for data entry and results Additional calculations of air-sea CO2 fluxes (for surface water calculations) The ability to tag data with sample name, comments, date, time, and latitude/longitude The ability to use the system time and date and latitude/ longitude (automatic retrieval of latitude and longitude available on iPhone? 3, 3GS, 4, and Windows? hosts with an attached National Marine Electronics Association (NMEA)-enabled GPS) The ability to process multiple files in a batch processing mode An option to save sample information, data input, and calculated results as a comma-separated value (CSV) file for use with Microsoft Excel, ArcGIS,? or other applications An option to export points with geographic coordinates as a KMZ file for viewing and editing in Google EarthTM

  13. Mendel,MD: A user-friendly open-source web tool for analyzing WES and WGS in the diagnosis of patients with Mendelian disorders.

    Science.gov (United States)

    G C C L Cardenas, Raony; D Linhares, Natália; L Ferreira, Raquel; Pena, Sérgio D J

    2017-06-01

    Whole exome and whole genome sequencing have both become widely adopted methods for investigating and diagnosing human Mendelian disorders. As pangenomic agnostic tests, they are capable of more accurate and agile diagnosis compared to traditional sequencing methods. This article describes new software called Mendel,MD, which combines multiple types of filter options and makes use of regularly updated databases to facilitate exome and genome annotation, the filtering process and the selection of candidate genes and variants for experimental validation and possible diagnosis. This tool offers a user-friendly interface, and leads clinicians through simple steps by limiting the number of candidates to achieve a final diagnosis of a medical genetics case. A useful innovation is the "1-click" method, which enables listing all the relevant variants in genes present at OMIM for perusal by clinicians. Mendel,MD was experimentally validated using clinical cases from the literature and was tested by students at the Universidade Federal de Minas Gerais, at GENE-Núcleo de Genética Médica in Brazil and at the Children's University Hospital in Dublin, Ireland. We show in this article how it can simplify and increase the speed of identifying the culprit mutation in each of the clinical cases that were received for further investigation. Mendel,MD proved to be a reliable web-based tool, being open-source and time efficient for identifying the culprit mutation in different clinical cases of patients with Mendelian Disorders. It is also freely accessible for academic users on the following URL: https://mendelmd.org.

  14. Experimental results and a user-friendly model of heat transfer from a thin film resistance temperature detector

    Energy Technology Data Exchange (ETDEWEB)

    Post, Julian W. [Smart Materials and MEMS Laboratory, Department of Applied Science, University of Arkansas at Little Rock, 2801 South University, ETAS 575, Little Rock, AR 72204-1099 (United States); Bhattacharyya, A. [Smart Materials and MEMS Laboratory, Department of Applied Science, University of Arkansas at Little Rock, 2801 South University, ETAS 575, Little Rock, AR 72204-1099 (United States)], E-mail: axbhattachar@ualr.edu; Imran, M. [Kohler Co., Sheridan, AR 72150 (United States)

    2009-01-15

    The research reported in this paper has focused on the different modes of heat transfer - conductive (to the substrate), conductive and convective (to the environment) and radiative (to the environment) - from an on-chip resistance temperature detector (RTD). The study has been carried out at various input voltages, various pressures ranging from atmospheric to vacuum, and for two classes of platforms for the device - thermal insulators (glass wool and ceramic), and a thermal conductor (aluminum block). The transient temperature-time response of the RTD under the various conditions stated above was recorded. A heat transfer model approximately accounting for all the modes of heat transfer was introduced. The calibration parameters of the model allowed us to quantify the different modes of heat transfer. The model uncovers the fact that the heat losses to the environment via conduction and convection are almost as much as the heat lost by radiation (radiative effects were unequivocally confirmed experimentally). Compared to these losses, conductive heat losses from the RTD to its underlying substructure are far more dominant (almost five times). We also give an analysis originating from the exact form of conservation of energy and demonstrate that the use of the simplified model has led to the most dominant heat transfer mode of conduction to the substrate being underestimated by no more than 7.89% (at the highest input power tested)

  15. The heat-transfer method: a versatile low-cost, label-free, fast, and user-friendly readout platform for biosensor applications.

    Science.gov (United States)

    van Grinsven, Bart; Eersels, Kasper; Peeters, Marloes; Losada-Pérez, Patricia; Vandenryt, Thijs; Cleij, Thomas J; Wagner, Patrick

    2014-08-27

    In recent years, biosensors have become increasingly important in various scientific domains including medicine, biology, and pharmacology, resulting in an increased demand for fast and effective readout techniques. In this Spotlight on Applications, we report on the recently developed heat-transfer method (HTM) and illustrate the use of the technique by zooming in on four established bio(mimetic) sensor applications: (i) mutation analysis in DNA sequences, (ii) cancer cell identification through surface-imprinted polymers, (iii) detection of neurotransmitters with molecularly imprinted polymers, and (iv) phase-transition analysis in lipid vesicle layers. The methodology is based on changes in heat-transfer resistance at a functionalized solid-liquid interface. To this extent, the device applies a temperature gradient over this interface and monitors the temperature underneath and above the functionalized chip in time. The heat-transfer resistance can be obtained by dividing this temperature gradient by the power needed to achieve a programmed temperature. The low-cost, fast, label-free and user-friendly nature of the technology in combination with a high degree of specificity, selectivity, and sensitivity makes HTM a promising sensor technology.

  16. Sex, shoulder pain, and range of motion in manual wheelchair users

    Directory of Open Access Journals (Sweden)

    Karla K. Wessels, MS, ATC

    2013-05-01

    Full Text Available Upwards of 70% of manual wheelchair users (MWUs experience shoulder pain. Pain is more prevalent among females than males. The causes of this sex discrepancy are not understood. Decreased range of motion (ROM has been suggested as a major contributor, but the interaction of sex, ROM, and shoulder pain has not been investigated, thus the purpose of this investigation. We divided 30 MWUs (18 males, 12 females; 21.93 +/– 3.77 yr into two groups based on self-reported shoulder pain: pain group (n = 14; 9 males, 5 females and no pain group (n = 16; 9 males, 7 females. We used a digital goniometer to assess ROM. Participants’ shoulder active and passive ROMs were tested bilaterally on the following joint motions: flexion, extension, abduction, adduction, internal rotation, and external rotation. We used a visual analog scale to assess shoulder pain. Of the participants, 47% reported shoulder pain. Overall, the no pain group had greater ROM than the pain group, with further analysis revealing this association was only significant in females during extension (p < 0.05. ROM impairments were only present in extension in females with shoulder pain. The mechanism underlying this sex difference is not clear.

  17. Compassionate Friends

    Science.gov (United States)

    ... The services provided by the... Help Support Compassionate Friends Rest assured, every donation we receive is used ... remembered.... Read More... Sign Up for the Compassionate Friends Newsletter Find Support Chapters To The Newly Bereaved ...

  18. iMet-Q: A User-Friendly Tool for Label-Free Metabolomics Quantitation Using Dynamic Peak-Width Determination.

    Directory of Open Access Journals (Sweden)

    Hui-Yin Chang

    Full Text Available Efficient and accurate quantitation of metabolites from LC-MS data has become an important topic. Here we present an automated tool, called iMet-Q (intelligent Metabolomic Quantitation, for label-free metabolomics quantitation from high-throughput MS1 data. By performing peak detection and peak alignment, iMet-Q provides a summary of quantitation results and reports ion abundance at both replicate level and sample level. Furthermore, it gives the charge states and isotope ratios of detected metabolite peaks to facilitate metabolite identification. An in-house standard mixture and a public Arabidopsis metabolome data set were analyzed by iMet-Q. Three public quantitation tools, including XCMS, MetAlign, and MZmine 2, were used for performance comparison. From the mixture data set, seven standard metabolites were detected by the four quantitation tools, for which iMet-Q had a smaller quantitation error of 12% in both profile and centroid data sets. Our tool also correctly determined the charge states of seven standard metabolites. By searching the mass values for those standard metabolites against Human Metabolome Database, we obtained a total of 183 metabolite candidates. With the isotope ratios calculated by iMet-Q, 49% (89 out of 183 metabolite candidates were filtered out. From the public Arabidopsis data set reported with two internal standards and 167 elucidated metabolites, iMet-Q detected all of the peaks corresponding to the internal standards and 167 metabolites. Meanwhile, our tool had small abundance variation (≤ 0.19 when quantifying the two internal standards and had higher abundance correlation (≥ 0.92 when quantifying the 167 metabolites. iMet-Q provides user-friendly interfaces and is publicly available for download at http://ms.iis.sinica.edu.tw/comics/Software_iMet-Q.html.

  19. Spectrum-Malaria: a user-friendly projection tool for health impact assessment and strategic planning by malaria control programmes in sub-Saharan Africa.

    Science.gov (United States)

    Hamilton, Matthew; Mahiane, Guy; Werst, Elric; Sanders, Rachel; Briët, Olivier; Smith, Thomas; Cibulskis, Richard; Cameron, Ewan; Bhatt, Samir; Weiss, Daniel J; Gething, Peter W; Pretorius, Carel; Korenromp, Eline L

    2017-02-10

    Scale-up of malaria prevention and treatment needs to continue but national strategies and budget allocations are not always evidence-based. This article presents a new modelling tool projecting malaria infection, cases and deaths to support impact evaluation, target setting and strategic planning. Nested in the Spectrum suite of programme planning tools, the model includes historic estimates of case incidence and deaths in groups aged up to 4, 5-14, and 15+ years, and prevalence of Plasmodium falciparum infection (PfPR) among children 2-9 years, for 43 sub-Saharan African countries and their 602 provinces, from the WHO and malaria atlas project. Impacts over 2016-2030 are projected for insecticide-treated nets (ITNs), indoor residual spraying (IRS), seasonal malaria chemoprevention (SMC), and effective management of uncomplicated cases (CMU) and severe cases (CMS), using statistical functions fitted to proportional burden reductions simulated in the P. falciparum dynamic transmission model OpenMalaria. In projections for Nigeria, ITNs, IRS, CMU, and CMS scale-up reduced health burdens in all age groups, with largest proportional and especially absolute reductions in children up to 4 years old. Impacts increased from 8 to 10 years following scale-up, reflecting dynamic effects. For scale-up of each intervention to 80% effective coverage, CMU had the largest impacts across all health outcomes, followed by ITNs and IRS; CMS and SMC conferred additional small but rapid mortality impacts. Spectrum-Malaria's user-friendly interface and intuitive display of baseline data and scenario projections holds promise to facilitate capacity building and policy dialogue in malaria programme prioritization. The module's linking to the OneHealth Tool for costing will support use of the software for strategic budget allocation. In settings with moderately low coverage levels, such as Nigeria, improving case management and achieving universal coverage with ITNs could achieve

  20. iMet-Q: A User-Friendly Tool for Label-Free Metabolomics Quantitation Using Dynamic Peak-Width Determination.

    Science.gov (United States)

    Chang, Hui-Yin; Chen, Ching-Tai; Lih, T Mamie; Lynn, Ke-Shiuan; Juo, Chiun-Gung; Hsu, Wen-Lian; Sung, Ting-Yi

    2016-01-01

    Efficient and accurate quantitation of metabolites from LC-MS data has become an important topic. Here we present an automated tool, called iMet-Q (intelligent Metabolomic Quantitation), for label-free metabolomics quantitation from high-throughput MS1 data. By performing peak detection and peak alignment, iMet-Q provides a summary of quantitation results and reports ion abundance at both replicate level and sample level. Furthermore, it gives the charge states and isotope ratios of detected metabolite peaks to facilitate metabolite identification. An in-house standard mixture and a public Arabidopsis metabolome data set were analyzed by iMet-Q. Three public quantitation tools, including XCMS, MetAlign, and MZmine 2, were used for performance comparison. From the mixture data set, seven standard metabolites were detected by the four quantitation tools, for which iMet-Q had a smaller quantitation error of 12% in both profile and centroid data sets. Our tool also correctly determined the charge states of seven standard metabolites. By searching the mass values for those standard metabolites against Human Metabolome Database, we obtained a total of 183 metabolite candidates. With the isotope ratios calculated by iMet-Q, 49% (89 out of 183) metabolite candidates were filtered out. From the public Arabidopsis data set reported with two internal standards and 167 elucidated metabolites, iMet-Q detected all of the peaks corresponding to the internal standards and 167 metabolites. Meanwhile, our tool had small abundance variation (≤ 0.19) when quantifying the two internal standards and had higher abundance correlation (≥ 0.92) when quantifying the 167 metabolites. iMet-Q provides user-friendly interfaces and is publicly available for download at http://ms.iis.sinica.edu.tw/comics/Software_iMet-Q.html.

  1. QDD version 3.1: a user-friendly computer program for microsatellite selection and primer design revisited: experimental validation of variables determining genotyping success rate.

    Science.gov (United States)

    Meglécz, Emese; Pech, Nicolas; Gilles, André; Dubut, Vincent; Hingamp, Pascal; Trilles, Aurélie; Grenier, Rémi; Martin, Jean-François

    2014-11-01

    Microsatellite marker development has been greatly simplified by the use of high-throughput sequencing followed by in silico microsatellite detection and primer design. However, the selection of markers designed by the existing pipelines depends either on arbitrary criteria, or older studies on PCR success. Based on wet laboratory experiments, we have identified the following factors that are most likely to influence genotyping success rate: alignment score between the primers and the amplicon; the distance between primers and microsatellites; the length of the PCR product; target region complexity and the number of reads underlying the sequence. The QDD pipeline has been modified to include these most pertinent factors in the output to help the selection of markers. Furthermore, new features are also included in the present version: (i) not only raw sequencing reads are accepted as input, but also contigs, allowing the analysis of assembled high-coverage data; (ii) input data can be both in fasta and fastq format to facilitate the use of Illumina and IonTorrent reads; (iii) A comparison to known transposable elements allows their detection; (iv) A contamination check can be carried out by BLASTing potential markers against the nucleotide (nt) database of NCBI; (v) QDD3 is now also available imbedded into a virtual machine making installation easier and operating system independent. It can be used both on command-line version as well as integrated into a Galaxy server, providing a user-friendly interface, as well as the possibility to utilize a large variety of NGS tools. © 2014 John Wiley & Sons Ltd.

  2. 人性化设计在家居装饰设计中的应用分析%User-friendly Design in Home Decoration Design Analysis

    Institute of Scientific and Technical Information of China (English)

    向舒

    2015-01-01

    从当代社会的发展趋势看,人性化设计越来越受到重视,提倡“以人为本”,人的思想已成为设计主流。居家环境的人性化设计是现代家居装饰设计的发展趋势,因此,在家居装饰设计中进行人性化设计的研究具有重要的现实意义。通过阐述人性化设计的内涵,对其在家居装饰设计中存在的差异进行研究,进一步分析人性化设计存在的意义,并且通过案例分析,使人性化设计观念更具表现性。%From the development trend of contemporary society, the human design more and more attention, to promote“people-oriented”, the human mind has become the mainstream design. Humanized design the home environment is the development trend of modern home decoration design, therefore, studies of human design in home decoration design has important practical significance. Through elaborate the meaning of human design, home decoration design their differences that exist to study further analyzes the significance of the presence of user-friendly design, and case analysis, design concept makes sex more expressive.

  3. Friends' Discovery Camp

    Science.gov (United States)

    Seymour, Seth

    2008-01-01

    This article features Friends' Discovery Camp, a program that allows children with and without autism spectrum disorder to learn and play together. In Friends' Discovery Camp, campers take part in sensory-rich experiences, ranging from hands-on activities and performing arts to science experiments and stories teaching social skills. Now in its 7th…

  4. Modelling surface hydrology with DR2-SAGA 1.0: development of a user-friendly interface for hillslope water balance assessments

    Science.gov (United States)

    López-Montero, Teresa; López-Vicente, Manuel; Navas, Ana

    2013-04-01

    Soil moisture variability and the depth of water stored in the arable layer of the soil are important topics in agricultural research and rangeland management. Additionally, runoff triggers soil detachment and sediment delivery, and thus is one of the most important factors in the soil erosion dynamic. Overland flow generation and accumulation are non-linear and scale-dependent processes and the development of prediction models helps researchers evaluate different scenarios at different temporal and spatial scales. In this study, we present the DR2-SAGA 1.0 module to the scientific community. The DR2 (Distributed Rainfall-Runoff) water balance model computes the depth of water stored within the soil profile (Waa) distinguishing five scenarios of the upslope contributing area, infiltration processes and climatic parameters, and assesses the soil moisture status (SMS) throughout the year for an average monthly rainfall event. The SAGA program is a free Geographical Information System (GIS) with support for vector and, specially, raster data. Its foundation is its Application Programming Interface (API), which provides data object models and basic definitions for the programming of scientific modules. Module libraries contain the scientific methods and are developed using C++ code. The new module was run in a medium size mountain Mediterranean catchment (246 ha; Spanish Central Pre-Pyrenees) at high spatial resolution (5 x 5 meters of cell size). The Estaña Lakes Catchment is affected by karstic processes which explain the presence of 15 endorheic sub-catchments and three fresh-water lakes. Additionally, this area is ungauged and offers the opportunity to test the performance of the new module in a non-conventional landscape. DR2-SAGA 1.0 demands 16 inputs and generates monthly and annual maps of initial and effective runoff depth, Waa and SMS. One user-friendly tab was created with SAGA 2.0.8 for each input and output file. The new module also includes a water

  5. Applying the Training Range Environmental Evaluation and Characterization System (TREECS) (User Guide)

    Science.gov (United States)

    2012-08-01

    site is included with the TREECS™ install along with the Web site for Visual MINTEQ , which is a user-added Web site also included with the install...MIDAS is maintained by the Defense Ammunition Center (DAC). Visual MINTEQ is software for chemical equilibrium speciation modeling and could be...helpful for estimating solubility for various inorganic constituents, such as metals. The use of Visual MINTEQ for estimating the solubility of lead and

  6. HBIM and augmented information: towards a wider user community of image and range-based reconstructions

    Science.gov (United States)

    Barazzetti, L.; Banfi, F.; Brumana, R.; Oreni, D.; Previtali, M.; Roncoroni, F.

    2015-08-01

    This paper describes a procedure for the generation of a detailed HBIM which is then turned into a model for mobile apps based on augmented and virtual reality. Starting from laser point clouds, photogrammetric data and additional information, a geometric reconstruction with a high level of detail can be carried out by considering the basic requirements of BIM projects (parametric modelling, object relations, attributes). The work aims at demonstrating that a complex HBIM can be managed in portable devices to extract useful information not only for expert operators, but also towards a wider user community interested in cultural tourism.

  7. SAFARI: Seismo-Acoustic Fast Field Algorithm for Range-Independent Environments. User’s Guide

    Science.gov (United States)

    1988-09-01

    as func- tion of range. - 98 - SiACLANTW"N $74lS 7- Running SAFARI-FIP * 7.3.5. SAFARI-FIP case 5: Beam propagation In this laIt example it is...195. [6] PEKERIS, C.L. Theory of propagation of explosive sound in shallow water. Memoirs , Geological Society of America, 27, 1948. [71 JARDETZKY, W.S

  8. A Wide-range Survey on Recall-Based Graphical User Authentications Algorithms Based on ISO and Attack Patterns

    Directory of Open Access Journals (Sweden)

    Arash Habibi Lashkari

    2009-12-01

    Full Text Available Nowadays, user authentication is one of the important topics in information security. Text-based strong password schemes could provide with certain degree of security. However, the fact that strong passwords being difficult to memorize often leads their owners to write them down on papers or even save them in a computer file. Graphical user authentication (GUA has been proposed as a possible alternative solution to text-based authentication, motivated particularly by the fact that humans can remember images better than text. In recent years, many networks, computer systems and Internet-based environments try used GUA technique for their user’s authentication. All of GUA algorithms have two different aspects which are usability and security. Unfortunately, none of graphical algorithms were being able to cover both of these aspects at the same time. This paper presents a wide-range survey on the pure and cued recall-based algorithms in GUA, based on ISO standards for usability and attack patterns standards for security. After explain usability ISO standards and attack patterns international standards, we try to collect the major attributes of usability and security in GUA. Finally, try to make comparison tables among all recall-based algorithms based on usability attributes and attack patterns those we found. Keywords - Recall-Based Graphical User Authentication; Graphical Password; Usability and security; ISO 9241-11; ISO 9126, ISO 13407; Attack Patterns; Brute force, Dictionary attacks; Guessing; Spyware; Shoulder surfing; Social engineering (description.

  9. Cooperative multi-user detection and ranging based on pseudo-random codes

    Science.gov (United States)

    Morhart, C.; Biebl, E. M.

    2009-05-01

    We present an improved approach for a Round Trip Time of Flight distance measurement system. The system is intended for the usage in a cooperative localisation system for automotive applications. Therefore, it is designed to address a large number of communication partners per measurement cycle. By using coded signals in a time divison multiple access order, we can detect a large number of pedestrian sensors with just one car sensor. We achieve this by using very short transmit bursts in combination with a real time correlation algorithm. Futhermore, the correlation approach offers real time data, concerning the time of arrival, that can serve as a trigger impulse for other comunication systems. The distance accuracy of the correlation result was further increased by adding a fourier interpolation filter. The system performance was checked with a prototype at 2.4 GHz. We reached a distance measurement accuracy of 12 cm at a range up to 450 m.

  10. Cooperative multi-user detection and ranging based on pseudo-random codes

    Directory of Open Access Journals (Sweden)

    C. Morhart

    2009-05-01

    Full Text Available We present an improved approach for a Round Trip Time of Flight distance measurement system. The system is intended for the usage in a cooperative localisation system for automotive applications. Therefore, it is designed to address a large number of communication partners per measurement cycle. By using coded signals in a time divison multiple access order, we can detect a large number of pedestrian sensors with just one car sensor. We achieve this by using very short transmit bursts in combination with a real time correlation algorithm. Futhermore, the correlation approach offers real time data, concerning the time of arrival, that can serve as a trigger impulse for other comunication systems. The distance accuracy of the correlation result was further increased by adding a fourier interpolation filter. The system performance was checked with a prototype at 2.4 GHz. We reached a distance measurement accuracy of 12 cm at a range up to 450 m.

  11. Friendly competition.

    Science.gov (United States)

    Chambers, David W

    2006-01-01

    Competition that is characterized by rules, often informal, agreed among mutually accepted participants, and that gives the competitors a special, advantageous status with others is called friendly competition. Dentists have engaged in it deeply and it is good for the profession. Friendly competition offers the advantages of spillover of commonly useful information and technologies, stimulation of innovation, a united and convenient face to customers and suppliers, and standards that promote growth. Friendly competition increases the size of the pie, regardless of market share. Paradoxically, this is even true for the little guy in the shadow of the giant. If carried to extremes, unfriendly competition leads to destroying competitors, the confusion of multiple rules, and encouragement of disruptive change.

  12. Close Friends

    Institute of Scientific and Technical Information of China (English)

    ChappellSargent

    2004-01-01

    As my friends ambled out the front door, I ran to the window, called good-bye, and stuck my tongue out at her. She spun around and returned the gesture, and we gave each other a final wave before parting

  13. Cyber Friendly Fire

    Energy Technology Data Exchange (ETDEWEB)

    Greitzer, Frank L.; Carroll, Thomas E.; Roberts, Adam D.

    2011-09-01

    Cyber friendly fire (FF) is a new concept that has been brought to the attention of Department of Defense (DoD) stakeholders through two workshops that were planned and conducted by the Air Force Research Laboratory (AFRL) and research conducted for AFRL by the Pacific Northwest National Laboratory. With this previous work in mind, we offer a definition of cyber FF as intentional offensive or defensive cyber/electronic actions intended to protect cyber systems against enemy forces or to attack enemy cyber systems, which unintentionally harms the mission effectiveness of friendly or neutral forces. Just as with combat friendly fire, a fundamental need in avoiding cyber FF is to maintain situation awareness (SA). We suggest that cyber SA concerns knowledge of a system's topology (connectedness and relationships of the nodes in a system), and critical knowledge elements such as the characteristics and vulnerabilities of the components that comprise the system (and that populate the nodes), the nature of the activities or work performed, and the available defensive (and offensive) countermeasures that may be applied to thwart network attacks. A training implication is to raise awareness and understanding of these critical knowledge units; an approach to decision aids and/or visualizations is to focus on supporting these critical knowledge units. To study cyber FF, we developed an unclassified security test range comprising a combination of virtual and physical devices that present a closed network for testing, simulation, and evaluation. This network offers services found on a production network without the associated costs of a real production network. Containing enough detail to appear realistic, this virtual and physical environment can be customized to represent different configurations. For our purposes, the test range was configured to appear as an Internet-connected Managed Service Provider (MSP) offering specialized web applications to the general public

  14. Automatic genomics: a user-friendly program for the automatic designing and plate loading of medium-throughput qPCR experiments.

    Science.gov (United States)

    Callejas, Sergio; Alvarez, Rebeca; Dopazo, Ana

    2011-01-01

    Quantitative PCR (qPCR) remains the method of choice for gene and microRNA (miRNA) expression studies. Many laboratories wish to automate some or all of the steps of medium-throughput qPCR experiments through the use of various types of liquid handling robots. However, it is not uncommon to find cases in which scripts provided by the robot supplier are too rigid for user-specific applications, do not include all the desired options, or are too complicated to be modified by a nonprofessional programmer. Here, we present Automatic Genomics, a program that allows users with a limited programming background to automate medium-throughput qPCR experiments by using commercially available liquid-handling robots. The user is able to optimize the plate design in terms of number of genes, number of samples, and controls.

  15. ECOMS-UDG. A User-friendly Data access Gateway to seasonal forecast datasets allowing R-based remote data access, visualization-validation, bias correction and downscaling

    Science.gov (United States)

    Santiago Cofiño, Antonio; Gutiérrez, José Manuel; Fernández, Jesús; Bedia, Joaquín; Vega, Manuel; Herrera, Sixto; Frías, María Dolores; Iturbide, Maialen; Magariño, Maria Eugenia; Manzanas, Rodrigo

    2016-04-01

    Seasonal forecasting data from state-or-the-art forecasting systems (e.g. NCEP/CFSv2 or ECMWF/System4) can be obtained directly from the data providers, but the resulting formats, aggregations and vocabularies may not be homogeneous across datasets, requiring some post processing. Moreover, different data policies hold for the various datasets - which are freely available only in some cases - and therefore data access may not be straightforward. Thus, obtaining seasonal climate forecast data is typically a time consuming task. The ECOMS-UDG (User Data Gateway for the ECOMS initiative) has been developed building in the ​User Data Gateway (UDG, http://meteo.unican.es/udg-wiki) in order to facilitate seasonal (re)forecast data access to end users. The required variables have been downloaded from data providers and stored locally in a THREDDS data server implementing fine-grained user authorization. Thus, users can efficiently retrieve the subsets that best suits their particular research aims (typically surface variables for certain regions, periods and/or ensemble members) from a large volume of information. Moreover, an interface layer developed in R allows remote data exploration, access (including homogenization, collocation and sub-setting) and the integration of ECOMS-UDG with a number of R packages developed in the framework of ECOMS for forecast visualization, validation, bias correction and downscaling. This unique framework oriented to climate services allows users from different sectors to easily access seasonal forecasting data (typically surface variables), calibrating and/or downscaling (using upper air information from large scale predictors) this data at local level and validating the different results (using observations). The documentation delivered with the packages includes worked examples showing that the whole visualization, bias correction and/or downscaling tasks requires only a few lines of code and are fully reproducible and adaptable to

  16. A user-friendly, menu-driven, language-free laser characteristics curves graphing program for desk-top IBM PC compatible computers

    Science.gov (United States)

    Klutz, Glenn

    1989-01-01

    A facility was established that uses collected data and feeds it into mathematical models that generate improved data arrays by correcting for various losses, base line drift, and conversion to unity scaling. These developed data arrays have headers and other identifying information affixed and are subsequently stored in a Laser Materials and Characteristics data base which is accessible to various users. The two part data base: absorption - emission spectra and tabulated data, is developed around twelve laser models. The tabulated section of the data base is divided into several parts: crystalline, optical, mechanical, and thermal properties; aborption and emission spectra information; chemical name and formulas; and miscellaneous. A menu-driven, language-free graphing program will reduce and/or remove the requirement that users become competent FORTRAN programmers and the concomitant requirement that they also spend several days to a few weeks becoming conversant with the GEOGRAF library and sequence of calls and the continual refreshers of both. The work included becoming thoroughly conversant with or at least very familiar with GEOGRAF by GEOCOMP Corp. The development of the graphing program involved trial runs of the various callable library routines on dummy data in order to become familiar with actual implementation and sequencing. This was followed by trial runs with actual data base files and some additional data from current research that was not in the data base but currently needed graphs. After successful runs, with dummy and real data, using actual FORTRAN instructions steps were undertaken to develop the menu-driven language-free implementation of a program which would require the user only know how to use microcomputers. The user would simply be responding to items displayed on the video screen. To assist the user in arriving at the optimum values needed for a specific graph, a paper, and pencil check list was made available to use on the trial runs.

  17. Dynamo: a flexible, user-friendly development tool for subtomogram averaging of cryo-EM data in high-performance computing environments.

    Science.gov (United States)

    Castaño-Díez, Daniel; Kudryashev, Mikhail; Arheit, Marcel; Stahlberg, Henning

    2012-05-01

    Dynamo is a new software package for subtomogram averaging of cryo Electron Tomography (cryo-ET) data with three main goals: first, Dynamo allows user-transparent adaptation to a variety of high-performance computing platforms such as GPUs or CPU clusters. Second, Dynamo implements user-friendliness through GUI interfaces and scripting resources. Third, Dynamo offers user-flexibility through a plugin API. Besides the alignment and averaging procedures, Dynamo includes native tools for visualization and analysis of results and data, as well as support for third party visualization software, such as Chimera UCSF or EMAN2. As a demonstration of these functionalities, we studied bacterial flagellar motors and showed automatically detected classes with absent and present C-rings. Subtomogram averaging is a common task in current cryo-ET pipelines, which requires extensive computational resources and follows a well-established workflow. However, due to the data diversity, many existing packages offer slight variations of the same algorithm to improve results. One of the main purposes behind Dynamo is to provide explicit tools to allow the user the insertion of custom designed procedures - or plugins - to replace or complement the native algorithms in the different steps of the processing pipeline for subtomogram averaging without the burden of handling parallelization. Custom scripts that implement new approaches devised by the user are integrated into the Dynamo data management system, so that they can be controlled by the GUI or the scripting capacities. Dynamo executables do not require licenses for third party commercial software. Sources, executables and documentation are freely distributed on http://www.dynamo-em.org.

  18. My Friends

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    学生习作: I have three friends. They is1 Jack, Gina and Kate. Jack’s favorite subject is P.E.. He likes it because it is interested2. He has P.E. on Monday. Gina’s favorite subject is music. She thinks it is very much3 relaxing. She likes to listen4 music after class. She has music on

  19. Franklin: User Experiences

    Energy Technology Data Exchange (ETDEWEB)

    National Energy Research Supercomputing Center; He, Yun (Helen); Kramer, William T.C.; Carter, Jonathan; Cardo, Nicholas

    2008-05-07

    The newest workhorse of the National Energy Research Scientific Computing Center is a Cray XT4 with 9,736 dual core nodes. This paper summarizes Franklin user experiences from friendly early user period to production period. Selected successful user stories along with top issues affecting user experiences are presented.

  20. Microarray Я US: a user-friendly graphical interface to Bioconductor tools that enables accurate microarray data analysis and expedites comprehensive functional analysis of microarray results

    Directory of Open Access Journals (Sweden)

    Dai Yilin

    2012-06-01

    Full Text Available Abstract Background Microarray data analysis presents a significant challenge to researchers who are unable to use the powerful Bioconductor and its numerous tools due to their lack of knowledge of R language. Among the few existing software programs that offer a graphic user interface to Bioconductor packages, none have implemented a comprehensive strategy to address the accuracy and reliability issue of microarray data analysis due to the well known probe design problems associated with many widely used microarray chips. There is also a lack of tools that would expedite the functional analysis of microarray results. Findings We present Microarray Я US, an R-based graphical user interface that implements over a dozen popular Bioconductor packages to offer researchers a streamlined workflow for routine differential microarray expression data analysis without the need to learn R language. In order to enable a more accurate analysis and interpretation of microarray data, we incorporated the latest custom probe re-definition and re-annotation for Affymetrix and Illumina chips. A versatile microarray results output utility tool was also implemented for easy and fast generation of input files for over 20 of the most widely used functional analysis software programs. Conclusion Coupled with a well-designed user interface, Microarray Я US leverages cutting edge Bioconductor packages for researchers with no knowledge in R language. It also enables a more reliable and accurate microarray data analysis and expedites downstream functional analysis of microarray results.

  1. Privacy-Preserving and Efficient Friend Recommendation in Online Social Networks

    Directory of Open Access Journals (Sweden)

    Bharath K. Samanthula

    2015-08-01

    Full Text Available The popularity of online social networks (OSNs is on constant rise due to various advantages, including online communication and sharing information of interest among friends. It is often that users want to make new friends to expand their social connections as well as to obtain information from a broad range of people. Friend recommendation is a very important application in many OSNs and has been studied extensively in the recent past. However,with the growing concerns about user privacy, there is a strong need to develop privacy-preserving friend recommendation methods for social networks. In this paper, we propose two novel methods to recommend friends for a given user by using the common neighbors proximity measure in a privacy-preserving manner. The first method is based on the properties of an additive homomorphic encryption scheme and also utilizes a universal hash function for efficiency purpose. The second method utilizes the concept of protecting the source privacy through anonymousmessage routing and recommends friends accurately and efficiently. In addition, we empirically compare the efficiency and accuracy of the proposed protocols, and address the implementation details of the two methods in practice. The proposed protocols provide a trade-off among security, accuracy, and efficiency; thus, users or the network provider can choose between these two protocols depending on the underlying requirements.

  2. User-Friendly Data-Sharing Practices for Fostering Collaboration within a Research Network: Roles of a Vanguard Center for a Community-Based Study.

    Science.gov (United States)

    Lee, Jae Eun; Sung, Jung Hye; Barnett, M Edwina; Norris, Keith

    2015-12-22

    Although various attempts have been made to build collaborative cultures for data sharing, their effectiveness is still questionable. The Jackson Heart Study (JHS) Vanguard Center (JHSVC) at the NIH-funded Research Centers in Minority Institutions (RCMI) Translational Research Network (RTRN) Data Coordinating Center (DCC) may be a new concept in that the data are being shared with a research network where a plethora of scientists/researchers are working together to achieve their common goal. This study describes the current practices to share the JHS data through the mechanism of JHSVC. The JHS is the largest single-site cohort study to prospectively investigate the determinants of cardiovascular disease among African-Americans. It has adopted a formal screened access method through a formalized JHSVC mechanism, in which only a qualified scientist(s) can access the data. The role of the DCC was to help RTRN researchers explore hypothesis-driven ideas to enhance the output and impact of JHS data through customized services, such as feasibility tests, data querying, manuscript proposal development and data analyses for publication. DCC has implemented these various programs to facilitate data utility. A total of 300 investigators attended workshops and/or received training booklets. DCC provided two online and five onsite workshops and developed/distributed more than 250 copies of the booklet to help potential data users understand the structure of and access to the data. Information on data use was also provided through the RTRN website. The DCC efforts led to the production of five active manuscript proposals, seven completed publications, 11 presentations and four NIH grant proposals. These outcomes resulted from activities during the first four years; over the last couple of years, there were few new requests. Our study suggested that DCC-customized services enhanced the accessibility of JHS data and their utility by RTRN researchers and helped to achieve the

  3. Environmentally friendly and biobased lubricants

    Science.gov (United States)

    Biobased and environmentally friendly lubricants are finding applications in many areas ranging from hydraulic fluids to grease. They offer excellent biodegradability and very low ecotoxicity; high viscosity index; improved tribological properties; lower volatility and flash points relative to petro...

  4. User-Friendly Data-Sharing Practices for Fostering Collaboration within a Research Network: Roles of a Vanguard Center for a Community-Based Study

    Directory of Open Access Journals (Sweden)

    Jae Eun Lee

    2015-12-01

    Full Text Available Although various attempts have been made to build collaborative cultures for data sharing, their effectiveness is still questionable. The Jackson Heart Study (JHS Vanguard Center (JHSVC at the NIH-funded Research Centers in Minority Institutions (RCMI Translational Research Network (RTRN Data Coordinating Center (DCC may be a new concept in that the data are being shared with a research network where a plethora of scientists/researchers are working together to achieve their common goal. This study describes the current practices to share the JHS data through the mechanism of JHSVC. The JHS is the largest single-site cohort study to prospectively investigate the determinants of cardiovascular disease among African-Americans. It has adopted a formal screened access method through a formalized JHSVC mechanism, in which only a qualified scientist(s can access the data. The role of the DCC was to help RTRN researchers explore hypothesis-driven ideas to enhance the output and impact of JHS data through customized services, such as feasibility tests, data querying, manuscript proposal development and data analyses for publication. DCC has implemented these various programs to facilitate data utility. A total of 300 investigators attended workshops and/or received training booklets. DCC provided two online and five onsite workshops and developed/distributed more than 250 copies of the booklet to help potential data users understand the structure of and access to the data. Information on data use was also provided through the RTRN website. The DCC efforts led to the production of five active manuscript proposals, seven completed publications, 11 presentations and four NIH grant proposals. These outcomes resulted from activities during the first four years; over the last couple of years, there were few new requests. Our study suggested that DCC-customized services enhanced the accessibility of JHS data and their utility by RTRN researchers and helped to

  5. Climate-friendly Default Rules

    DEFF Research Database (Denmark)

    Sunstein, Cass R.; Reisch, Lucia A.

    . The underlying reasons include the power of suggestion; inertia and procrastination; and loss aversion. If well-chosen, climate-friendly defaults are likely to have large effects in reducing the economic and environmental harms associated with various products and activities. In deciding whether to establish...... between climate-friendly products or services and alternatives that are potentially damaging to the climate but less expensive? The answer may well depend on the default rule. Indeed, climate-friendly default rules may well be a more effective tool for altering outcomes than large economic incentives...... climate-friendly defaults, choice architects (subject to legal constraints) should consider both consumer welfare and a wide range of other costs and benefits. Sometimes that assessment will argue strongly in favor of climate-friendly defaults, particularly when both economic and environmental...

  6. More user-friendly phosphines? Molecular structure of methylphosphine and its adduct with borane, studied by gas-phase electron diffraction and quantum chemical calculations

    OpenAIRE

    2008-01-01

    The molecular structures of methylphosphine (CH3PH2) and methylphosphine-borane (CH3PH2·BH3) have been determined from gas-phase electron diffraction data and rotational constants, employing the SARACEN method. The experimental geometric parameters generally showed a good agreement with those obtained using ab initio calculations and previous microwave spectroscopy studies. In order to assess the accuracy of the calculated structures a range of ab initio methods were used, including the CCSD(...

  7. The Puerto Rico Seismic Network Broadcast System: A user friendly GUI to broadcast earthquake messages, to generate shakemaps and to update catalogues

    Science.gov (United States)

    Velez, J.; Huerfano, V.; von Hillebrandt, C.

    2007-12-01

    estimation, and communication of earthquake information to the public. We develop a tool to help the PRSN personnel on duty with the generation of ShakeMaps for the felt events in Puerto Rico and the Virgin Islands. Automatic or reviewed locations came from different sources and the user can select the method to broadcast the message using several ways like direct email trough service lists, a server/client tool to push messages to a remote display client, generate shakemap web pages and update the catalogues.

  8. AG-NGS: a powerful and user-friendly computing application for the semi-automated preparation of next-generation sequencing libraries using open liquid handling platforms.

    Science.gov (United States)

    Callejas, Sergio; Álvarez, Rebeca; Benguria, Alberto; Dopazo, Ana

    2014-01-01

    Next-generation sequencing (NGS) is becoming one of the most widely used technologies in the field of genomics. Library preparation is one of the most critical, hands-on, and time-consuming steps in the NGS workflow. Each library must be prepared in an independent well, increasing the number of hours required for a sequencing run and the risk of human-introduced error. Automation of library preparation is the best option to avoid these problems. With this in mind, we have developed automatic genomics NGS (AG-NGS), a computing application that allows an open liquid handling platform to be transformed into a library preparation station without losing the potential of an open platform. Implementation of AG-NGS does not require programming experience, and the application has also been designed to minimize implementation costs. Automated library preparation with AG-NGS generated high-quality libraries from different samples, demonstrating its efficiency, and all quality control parameters fell within the range of optimal values.

  9. A Location Privacy Aware Friend Locator

    DEFF Research Database (Denmark)

    Siksnys, Laurynas; Thomsen, Jeppe Rishede; Saltenis, Simonas

    2009-01-01

    to trade their location privacy for quality of service, limiting the attractiveness of the services. The challenge is to develop a communication-efficient solution such that (i) it detects proximity between a user and the user’s friends, (ii) any other party is not allowed to infer the location of the user...

  10. Reflective writing: a user-friendly guide.

    Science.gov (United States)

    Hamilton, Stephen

    2016-09-08

    Stephen Hamilton, Nurse Education Consultant, Business Services Organisation. In this piece, he outlines the nature of the process of reflection to allay concerns that registered nurses may have about the process, as well as dispel any myths surrounding the purpose of reflection.

  11. The user-friendly industrial design

    Institute of Scientific and Technical Information of China (English)

    王洪超

    2015-01-01

    As people material needs are met, people start to lay claim to spiritual needs. Therefore, humanized design gradually become a trend in today’s design, products to use and easy to use, practical as the main reference point of design. Humanized design not only satisfied people experience of beauty in form, more satisfy the functional characteristics of the functional requirement of people, let people no longer strange to the product.

  12. Development of User-Friendly Credit Report

    Science.gov (United States)

    1990-12-01

    8217- 4 0 7 10ZI, $ 0 I * N153 STUDENT LOAN-PAYMENT DEFERRED TR SLMA LSC: K EL 03/8- $ £500 0 S / 88 1 8:𔄁OO 145-94 00000000 0 U s18:9 $ .5uu MO0LK30 A...Z_;540 C59 1 3K $ 7C I : N153 STUDENT LOAN-PAYMENT DEFERRED TR USAA FEDERAL Bb 06/86 $ 2.500 ti3/39 35 Z’ 00000Cl0100 1. 00001:35- 000i)00i)0 1 04/59...MO0I5 A : 5859400C8710 1 $ 0 I : N153 STUDENT LOAN - PAYMENT DEFERRED TR SEARS DC: 01/84 $ 1962 6 1 : 906DCOOOZ9 (.10000000 i 04/89 $ 1947 A * 8 91

  13. User-friendly LSB dictionary outside matter

    DEFF Research Database (Denmark)

    Møller, Bernt Carsten

    1994-01-01

    De dele af en ordbog, der omgiver ordlisten, gøres ud fra en funtionel betragtning til genstand for en tilrådet standard. Denne lægger vægten på indholdet og placeringen af de ordbogsdele, der har meta-karakter i forhold til ordlisten, især den uomgængelige Varedeklaration samt den mere tradition...

  14. NIH Loses a Friend

    Science.gov (United States)

    ... page please turn Javascript on. NIH Loses a Friend Past Issues / Fall 2009 Table of Contents Donald ... changingthefaceofmedicine/ . Sincerely, Donald West King, M.D., Chairman Friends of the National Library of Medicine Let Us ...

  15. Broad host range ProUSER vectors enable fast characterization of inducible promoters and optimization of p-coumaric acid production in Pseudomonas putida KT2440

    DEFF Research Database (Denmark)

    Calero Valdayo, Patricia; Ingemann Jensen, Sheila; Nielsen, Alex Toftgaard

    2016-01-01

    of ProUSER-reporter vectors was further created to characterize different inducible promoters. The PrhaB and Pm promoters were orthogonal and showed titratable, high, and homogeneous expression. To optimize the production of p-coumaric acid, P. putida was engineered to prevent degradation of tyrosine...... and p-coumaric acid. Pm and PrhaB were used to control the expression of a tyrosine ammonia lyase or AroG* and TyrA* involved in tyrosine production, respectively. Pathway expression was optimized by modulating inductions, resulting in small-scale p-coumaric acid production of 1.2 mM, the highest...... achieved in Pseudomonads under comparable conditions. With broad-host-range compatibility, the ProUSER vectors will serve as useful tools for optimizing gene expression in a variety of bacteria....

  16. User friendly analysis of MR investigations of the cerebral perfusion: Windows {sup trademark} -based image processing; Benutzerfreundliche Auswertung von MR-Untersuchungen der zerebralen Perfusion: Windows {sup trademark} -basierte Bildverarbeitung

    Energy Technology Data Exchange (ETDEWEB)

    Wittsack, H.J.; Moedder, U. [Inst. fuer Diagnostische Radiologie, Univ. Duesseldorf (Germany); Ritzl, A. [Inst. fuer Medizin, Forschungszentrum Juelich (Germany)

    2002-06-01

    Purpose: Quick and user-friendly analysis of perfusion and diffusion weighted MRI by means of interactive computer software. Method: A Windows {sup trademark} -based software was developed for analysis of perfusion (PWI) and diffusion (DWI) MR imaging. The computer program was developed in the programming language C++ using optimized algorithms, so that a high computing speed on Win95/98/NT systems is achieved. The established SVD algorithms of Oestergaard et al. for quantitative perfusion analysis were implemented. Results: Perfusion parameter maps of the cerebral blood flow (rCBF), the mean transit time (MTT) and the cerebral blood volume (rCBV) in consideration of the arterial input function (AIF) can be calculated and visualized using color tables. Additionally, the calculation of ''time-to-peak'' maps (TTP) and of maps of the percentage change in signal intensity (PC) is possible. The analysis of n = 10 normal persons shows perfusion values that agree with those found in the literature. Discussion: With the computer program developed here color-coded perfusion parameter maps can be calculated easily. Because of the high computing speed it is possible to get information about tissue perfusion on the basis of the large MR data sets even in acute investigations. (orig.) [German] Ziel: Schnelle und bedienerfreundliche Auswertung von perfusions- und diffusions-gewichteten MRT-Daten mittels interaktiver Auswertesoftware. Methoden: Eine Windows {sup trademark} -basierte Software zur Auswertung von Perfusions- (PWI) und Diffusions-MRT (DWI) wurde entwickelt. Das Computerprogramm wurde in der Programmiersprache C++ unter Verwendung optimierter Algorithmen entwickelt, so dass eine hohe Rechengeschwindigkeit auf Win95/98/NT-Systemen erreicht wird. Die etablierten SVD-Algorithmen von Oestergaard zur quantitativen Perfusions-Auswertung wurden implementiert. Ergebnisse: Perfusions-Parameterbilder des zerebralen Blutflusses (rCBF), der mittleren

  17. Safety, efficacy and pharmacokinetic evaluations of a new coated chloroquine tablet in a single-arm open-label non-comparative trial in Brazil: a step towards a user-friendly malaria vivax treatment.

    Science.gov (United States)

    Pereira, Dhelio; Daher, André; Zanini, Graziela; Maia, Ivan; Fonseca, Lais; Pitta, Luciana; Ruffato, Rosilene; Marchesini, Paola; Fontes, Cor Jesus

    2016-09-17

    Malaria remains a major public health problem, with half the world population at risk of contracting malaria. The effects of Plasmodium vivax on prosperity and longevity have been highlighted in several recent clinical case reports. The first line of vivax treatment drugs has seen no radical innovation for more than 60 years. This study introduces a subtle incremental innovation to vivax treatment: a chloroquine and primaquine co-blister. The co-blister includes a new chloroquine formulation incorporating coated tablets to mask the drug's bitter taste and user-friendly packaging containing tablets of each drug, which may improve patient adherence and facilitate the appropriate use of the drugs. This new formulation will replace the non-coated chloroquine distributed in Brazil. Patients were orally treated with 150 mg coated chloroquine tablets for 3 days: an initial 450 mg dose, followed by two 300 mg doses. The patients were treated concomitantly with two 15 mg primaquine tablets for 7-9 days, according to their weight. The primary objective of this study was to prove parasitological and clinical cure rates above 90 % by day 28. This single-arm open-label non-comparative trial was conducted according to the WHO recommended methodology for the surveillance of anti-malarial drug efficacy in the Brazilian Amazon. On day 28, the parasitological and clinical response was adequate in 98.8 % of patients (CI 95 % 93.4-100 %). The success rate on day 3 was 100 %, and the cumulative success rate by day 28 was 98.8 % (CI 95 % 91.7-99.8 %). There were no serious adverse events, with most adverse events classified as mild. The pharmacokinetic parameters of chloroquine analysed in whole blood dry spot samples showed mean (coefficient of variation) Cmax and AUC0-t values of 374.44 (0.35) and 3700.43 (0.36) ng/mL, respectively. This study reports an appropriate safety and efficacy profile of a new formulation of coated chloroquine tablets for vivax malaria

  18. Optimizing battery sizes of plug-in hybrid and extended range electric vehicles for different user types

    OpenAIRE

    REDELBACH Martin; Özdemir, Enver Doruk; Friedrich, Horst E.

    2014-01-01

    There are ambitious greenhouse gas emissions (GHG) targets for the manufacturers of light duty vehicles. To reduce the GHG emissions, plug-in hybrid electric vehicle (PHEV) and extended range electric vehicle (EREV) are promising powertrain technologies. However, the battery is still a very critical component due to the high production cost and heavy weight. This paper introduces a holistic approach for the optimization of the battery size of PHEVs and EREVs under German market conditions. Th...

  19. Caffeine: Friend or Foe?

    Science.gov (United States)

    Doepker, Candace; Lieberman, Harris R; Smith, Andrew Paul; Peck, Jennifer D; El-Sohemy, Ahmed; Welsh, Brian T

    2016-01-01

    The debate on the safety of and regulatory approaches for caffeine continues among various stakeholders and regulatory authorities. This decision-making process comes with significant challenges, particularly when considering the complexities of the available scientific data, making the formulation of clear science-based regulatory guidance more difficult. To allow for discussions of a number of key issues, the North American Branch of the International Life Sciences Institute (ILSI) convened a panel of subject matter experts for a caffeine-focused session entitled "Caffeine: Friend or Foe?," which was held during the 2015 ILSI Annual Meeting. The panelists' expertise covered topics ranging from the natural occurrence of caffeine in plants and interindividual metabolism of caffeine in humans to specific behavioral, reproductive, and cardiovascular effects related to caffeine consumption. Each presentation highlighted the potential risks, benefits, and challenges that inform whether caffeine exposure warrants concern. This paper aims to summarize the key topics discussed during the session.

  20. Students' Facebook "Friends": Public and Private Spheres

    Science.gov (United States)

    West, Anne; Lewis, Jane; Currie, Peter

    2009-01-01

    Friendship is highly significant during the university years. Facebook, widely used by students, is designed to facilitate communication with different groups of "friends". This exploratory study involved interviewing a sample of student users of Facebook: it focuses on the extent to which older adults, especially parents, are accepted as Facebook…

  1. Characterizing environment friendly tourists

    OpenAIRE

    Reinsberg, Cicilie; Vinje, Linn Therese

    2010-01-01

    The central aim of sustainable tourism research today is to find tourists that have a low environmental impact on destinations, which can also be defined as environment friendly tourists. The majority of earlier studies on this topic have focused on characteristics of ecotourists, assuming that these are the only tourists that are environment friendly. Few have tried to identify characteristics of environment friendly tourists using a sample from the general tourist population....

  2. "Friends" of Anglican Cathedrals: Norms and Values. Befriending, Friending or Misnomer?

    Science.gov (United States)

    Muskett, Judith A.

    2013-01-01

    Loyal supporters of Anglican cathedrals first subscribed to "Friends" associations in the late 1920s. Yet, in 1937, a journalist in "The Times" portrayed cathedrals as a "queer thing to be a friend of." Drawing on theories of friendship from a range of disciplines, and surveys of what has been proclaimed in the public…

  3. Environmentally Friendly Machining

    CERN Document Server

    Dixit, U S; Davim, J Paulo

    2012-01-01

    Environment-Friendly Machining provides an in-depth overview of environmentally-friendly machining processes, covering numerous different types of machining in order to identify which practice is the most environmentally sustainable. The book discusses three systems at length: machining with minimal cutting fluid, air-cooled machining and dry machining. Also covered is a way to conserve energy during machining processes, along with useful data and detailed descriptions for developing and utilizing the most efficient modern machining tools. Researchers and engineers looking for sustainable machining solutions will find Environment-Friendly Machining to be a useful volume.

  4. Friendly units for coldness

    CERN Document Server

    Fraundorf, P

    2006-01-01

    Measures of temperature that center around human experience get lots of use. Of course thermal physics insights of the last century have shown that reciprocal temperature (1/kT) has applications that temperature addresses less well. In addition to taking on negative absolute values under population inversion (e.g. of magnetic spins), bits and bytes turn 1/kT into an informatic measure of the thermal ambient for developing correlations within any complex system. We show here that, in the human-friendly units of bytes and food Calories, water freezes when 1/kT ~200 ZB/Cal or kT ~5 Cal/YB. Casting familiar benchmarks into these terms shows that habitable human space requires coldness values (part of the time, at least) between 0 and 40 ZB/Cal with respect body temperature ~100 degrees F, a range in kT of ~1 Cal/YB. Insight into these physical quantities underlying thermal equilibration may prove useful for budding scientists, as well as the general public, in years ahead.

  5. My Best Friend

    Institute of Scientific and Technical Information of China (English)

    刘清华; 郭克晴

    2002-01-01

    I am a middle school student,study in Yaoxia Middle School. I have a lot of good friends in this school. One of them, Li Kelong is my best friend. We are both fourteen years old. He has a round face and two big bright eyes. He is much stronger than me, but I am taller than him. I often call him Kelong for short.

  6. Deconstructing Female Friends

    Directory of Open Access Journals (Sweden)

    Adela MATEI

    2014-12-01

    Full Text Available One of Fay Weldon’s early novels, Female Friends (1975, published at the peak of her feminist ’phase’, deconstructs female and feminine stereotypes in order to present the writer’s own views on feminism. It speaks for a generation of women, who struggle to find their place in a male-dominated world, through three protagonists, who are neither happy, nor perfect. Narrated by the character Chloe, the novel revolves around her and her friends, Grace and Marjorie, with an aim at depicting the falsehood and hypocrisy that surround female friendship. It is precisely where Weldon’s specificity as a feminist writer lies: in her rendering the imperfections of women’s characters and relationships. This paper attempts to trace such elements of ‘fayminism’ in Female Friends by resorting to the tools of the feminist critic.

  7. ‘Dementia-friendly communities’ and being dementia friendly in healthcare settings

    Science.gov (United States)

    Lin, Shih-Yin

    2017-01-01

    Purpose of review This review discusses the concept of ‘dementia-friendly communities’ and summarizes the latest research and practice around such communities. This review also highlights important topic areas to be considered to promote dementia friendliness in healthcare settings. Recent findings Definitions of ‘dementia-friendly communities’ reflect the contemporary thinking of living with dementia (e.g., dementia as a disability, equal human rights, a sense of meaning). Existing research has covered a wide range of topic areas relevant to ‘dementia-friendly communities’. However, these studies remain qualitative and exploratory by nature and do not evaluate how dementia-friendly communities impact health and quality of life of people living with dementia and their caregivers. In healthcare settings, being dementia friendly can mean the inclusion of people with dementia in treatment discussion and decision-making, as well as the provision of first, adequate and appropriate service to people with dementia at an equivalent standard of any patient, second, person-centered care, and third, a physical environment following dementia-friendly design guidelines. Summary Research incorporating more robust study designs to evaluate dementia-friendly communities is needed. Being dementia-friendly in healthcare settings requires improvement in multiple areas – some may be achieved by environmental modifications while others may be improved by staff education. PMID:27997454

  8. The LOLITA User-Definable Template Interface

    OpenAIRE

    Košmelj, Katarina

    2001-01-01

    The development of user-definable templates interfaces which allow the user to design new templates definitions in a user-friendly way is a new issue in the field of information extraction. The LOLITA user-definable templates interface allows the user to define new templates using sentences in natural language text with a few restrictions and formal elements. This approach is rather different from previous approaches to information extraction which require developers to code the template defi...

  9. Nonverbal Communication in "Friends"

    Science.gov (United States)

    Chang, Yanrong

    2006-01-01

    This activity uses video clips from a popular sitcom, "Friends," to help students grasp the relational, rule-governed, and culture-specific nature of nonverbal communication. It opens students' eyes to nonverbal behaviors that are happening on a daily basis so that they not only master the knowledge but are able to apply it. While other popular…

  10. In Canada: Friendly Fire

    Science.gov (United States)

    Robertson, Heather-jane

    2004-01-01

    One of Canada's more frequently quoted political malapropisms is attributed to Robert Thompson, who sternly reminded his fellow parliamentarians in 1973 that "the Americans are our best friends, whether we like it or not." This cross-border friendship is partly expedient, partly geographic, partly genuine, sometimes one-sided, and almost always…

  11. My Beautiful Friend

    Institute of Scientific and Technical Information of China (English)

    雷全

    2004-01-01

    I have many toys in my room.Al-though they can’t speak,I treat them asmy friends.I like playing with them.Among them,my favorite is the beautiful girl-Barbiedoll.Her name is Kelly,same as my English name.She cameto my family a year ago as my birthday gift.

  12. Our Readers and Friends

    Institute of Scientific and Technical Information of China (English)

    1999-01-01

    In Shanghai,a rapidly-developing modern metropolisthere are a lot of foreign women who have moved with theirfamilies to live and work there.During their leisure time theytake sightseeing trips and study Chinese culture,so theybecome readers and friends of our magazine.Recently,at ourReaders Forum in Shanghai,women from the UK,Belgium,the

  13. Nonverbal Communication in "Friends"

    Science.gov (United States)

    Chang, Yanrong

    2006-01-01

    This activity uses video clips from a popular sitcom, "Friends," to help students grasp the relational, rule-governed, and culture-specific nature of nonverbal communication. It opens students' eyes to nonverbal behaviors that are happening on a daily basis so that they not only master the knowledge but are able to apply it. While other popular…

  14. My Good Friend

    Institute of Scientific and Technical Information of China (English)

    王雨航

    2008-01-01

    @@ I have a good friend. My mother even says that he is a member of our family. His name is Peter. He has two bright eyes, a small nose, a big mouth and a long tail. He is very lovely and looks like a white flowers. He likes drinking milk and eating meat.

  15. Feedback quality and environmentally friendly use of domestic central heating systems.

    Science.gov (United States)

    Sauer, J; Schmeink, C; Wastell, D G

    2007-06-01

    The study examined the influence of system-embedded feedback on user behaviour during the environmentally friendly operation of a central heating system. A PC-based simulation, called CHESS, was developed to model the critical features of a central heating system. After having received 30 min of training on the simulation task, 60 participants worked on a series of operational scenarios under different levels of system feedback. In addition to the collection of various performance measures (e.g. energy consumption, energy wastage), a range of user variables was collected (e.g. environmental concern). As hypothesized, the results showed that increased feedback resulted in improved environmentally friendly performance and, more importantly, the specific feedback indicator influenced the type of strategy used to improve human - machine system performance. A major implication is that system designers need to develop feedback indicators that are chiefly influenced by user behaviour and are largely immune to factors that are beyond the user's control (e.g. weather conditions).

  16. Photoshop with friends: A synchronous learning community for graphic design

    OpenAIRE

    Kim, Juho; Malley, Benjamin; Brandt, Joel; Dontcheva, Mira; Joseph, Diana; Gajos, Krzysztof Z.; Miller, Robert C

    2012-01-01

    Photoshop with Friends is an online community of learners exchanging just-in-time help on graphic design tasks. The system attempts to provide an interactive, visual, context-aware, and personalized mode of learning. Developed as a Facebook application, Photoshop with Friends allows users to help each other in live sessions, with built-in screen sharing, recording, and voice chat support. Major design decisions are guided by two laboratory studies that identified challenges in learning graphi...

  17. Friendly network robotics; Friendly network robotics

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    This paper summarizes the research results on the friendly network robotics in fiscal 1996. This research assumes an android robot as an ultimate robot and the future robot system utilizing computer network technology. The robot aiming at human daily work activities in factories or under extreme environments is required to work under usual human work environments. The human robot with similar size, shape and functions to human being is desirable. Such robot having a head with two eyes, two ears and mouth can hold a conversation with human being, can walk with two legs by autonomous adaptive control, and has a behavior intelligence. Remote operation of such robot is also possible through high-speed computer network. As a key technology to use this robot under coexistence with human being, establishment of human coexistent robotics was studied. As network based robotics, use of robots connected with computer networks was also studied. In addition, the R-cube (R{sup 3}) plan (realtime remote control robot technology) was proposed. 82 refs., 86 figs., 12 tabs.

  18. Letter from the Friends Chairman

    Science.gov (United States)

    ... Home Current Issue Past Issues Letter from the Friends Chairman Past Issues / Fall 2006 Table of Contents ... FNLM Chairman Paul Rogers converse at a recent Friends function at the National Library of Medicine. Photo ...

  19. Books Are Good Friends

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    正Books are our friends because they are bridges to knowledge.Knowledge is valuable because it enriches our life and brings us happiness.Almost all great men in the history of mankind loved books.We have every reason to believe it is the knowledge in books that led them to success.There is no genius without books.Because books give them knowledge and knowledge gives them

  20. TIA Software User's Manual

    Science.gov (United States)

    Cramer, K. Elliott; Syed, Hazari I.

    1995-01-01

    This user's manual describes the installation and operation of TIA, the Thermal-Imaging acquisition and processing Application, developed by the Nondestructive Evaluation Sciences Branch at NASA Langley Research Center, Hampton, Virginia. TIA is a user friendly graphical interface application for the Macintosh 2 and higher series computers. The software has been developed to interface with the Perceptics/Westinghouse Pixelpipe(TM) and PixelStore(TM) NuBus cards and the GW Instruments MacADIOS(TM) input-output (I/O) card for the Macintosh for imaging thermal data. The software is also capable of performing generic image-processing functions.

  1. Developing indicators for evaluation of age-friendly communities in Canada: process and results

    Directory of Open Access Journals (Sweden)

    H. Orpana

    2016-10-01

    Full Text Available Introduction: In 2006, the World Health Organization launched the Global Age-Friendly Cities Project to support active aging. Canada has a large number of age-friendly initiatives; however, little is known about the effectiveness and outcomes of age-friendly community (AFC initiatives. In addition, stakeholders report that they lack the capacity and tools to develop and conduct evaluations of their AFC initiatives. In order to address these gaps, the Public Health Agency of Canada developed indicators to support the evaluation of AFC initiatives relevant to a wide range of Canadian communities. These indicators meet the varied needs of communities, but are not designed to evaluate collective impact or enable cross-community comparisons. Methods: An evidence-based, iterative consultation approach was used to develop indicators for AFCs. This involved a literature review and an environmental scan. Two rounds of key expert and stakeholder consultations were conducted to rate potential indicators according to their importance, actionability and feasibility. A final list of indicators and potential measures were developed based on results from these consultations, as well as key policy considerations. Results: Thirty-nine indicators emerged across eight AFC domains plus four indicators related to long-term health and social outcomes. All meet the intended purpose of evaluating AFC initiatives at the community level. A user-friendly guide is available to support and share this work. Conclusion: The AFC indicators can help communities evaluate age-friendly initiatives, which is the final step in completing a cycle of the Pan-Canadian AFC milestones. Communities are encouraged to use the evaluation results to improve their AFC initiatives, thereby benefiting a broad range of Canadians.

  2. Climate friendly dietary guidelines

    DEFF Research Database (Denmark)

    Trolle, Ellen; Mogensen, Lisbeth; Thorsen, Anne Vibeke

    2014-01-01

    The aim of this study was to investigate how the present Danish diet could be changed in a climate friendly direction that follows the recommendations of a healthy diet. The carbon footprint (CF) of an average Danish diet was calculated and compared to CF of a recommended healthy diet by 1......%, if the healthy diet was eaten instead of the average current diet. However, if the diet was climate optimized by choosing foods with a low CF within the food groups; meat, vegetables and fruit, CF of this diet may be reduced by 23 % compared to CF of the average diet....

  3. Chimpanzees Trust Their Friends.

    Science.gov (United States)

    Engelmann, Jan M; Herrmann, Esther

    2016-01-25

    The identification and recruitment of trustworthy partners represents an important adaptive challenge for any species that relies heavily on cooperation [1, 2]. From an evolutionary perspective, trust is difficult to account for as it involves, by definition, a risk of non-reciprocation and defection by cheaters [3, 4]. One solution for this problem is to form close emotional bonds, i.e., friendships, which enable trust even in contexts where cheating would be profitable [5]. Little is known about the evolutionary origins of the human tendency to form close social bonds to overcome the trust problem. Studying chimpanzees (Pan troglodytes), one of our closest living relatives, is one way of identifying these origins. While a growing body of research indicates that at least some of the properties of close human relationships find parallels in the social bonds of chimpanzees [6-10] and that chimpanzees extend favors preferentially toward selected individuals [11-14], it is unclear whether such interactions are based on trust. To fill this gap in knowledge, we observed the social interactions of a group of chimpanzees and established dyadic friendship relations. We then presented chimpanzees with a modified, non-verbal version of the human trust game and found that chimpanzees trust their friends significantly more frequently than their non-friends. These results suggest that trust within closely bonded dyads is not unique to humans but rather has its evolutionary roots in the social relationships of our closest primate relatives.

  4. Three friendly walkers

    Science.gov (United States)

    Jensen, Iwan

    2017-01-01

    More than 15 years ago Guttmann and Vöge (2002 J. Stat. Plan. Inference 101 107), introduced a model of friendly walkers. Since then it has remained unsolved. In this paper we provide the exact solution to a closely allied model which essentially only differs in the boundary conditions. The exact solution is expressed in terms of the reciprocal of the generating function for vicious walkers which is a D-finite function. However, ratios of D-finite functions are inherently not D-finite and in this case we prove that the friendly walkers generating function is the solution to a non-linear differential equation with polynomial coefficients, it is in other words D-algebraic. We find using numerically exact calculations a conjectured expression for the generating function of the original model as a ratio of a D-finite function and the generating function for vicious walkers. We obtain an expression for this D-finite function in terms of a {{}2}{{F}1} hypergeometric function with a rational pullback and its first and second derivatives. Dedicated to Tony Guttmann on the occasion of his 70th birthday.

  5. Network-Friendly Gossiping

    Science.gov (United States)

    Serbu, Sabina; Rivière, Étienne; Felber, Pascal

    The emergence of large-scale distributed applications based on many-to-many communication models, e.g., broadcast and decentralized group communication, has an important impact on the underlying layers, notably the Internet routing infrastructure. To make an effective use of network resources, protocols should both limit the stress (amount of messages) on each infrastructure entity like routers and links, and balance as much as possible the load in the network. Most protocols use application-level metrics such as delays to improve efficiency of content dissemination or routing, but the extend to which such application-centric optimizations help reduce and balance the load imposed to the infrastructure is unclear. In this paper, we elaborate on the design of such network-friendly protocols and associated metrics. More specifically, we investigate random-based gossip dissemination. We propose and evaluate different ways of making this representative protocol network-friendly while keeping its desirable properties (robustness and low delays). Simulations of the proposed methods using synthetic and real network topologies convey and compare their abilities to reduce and balance the load while keeping good performance.

  6. Quora.com: Another Place for Users to Ask Questions

    Science.gov (United States)

    Ovadia, Steven

    2011-01-01

    Quora (www.quora.com) is a contemporary, web-based take on reference. Users post questions within Quora and other users answer the questions. Users can vote for and against answers (or not vote at all). It is users asking questions of friends and strangers and then sorting through the results. If the model sounds familiar, it's because it is.…

  7. Pedestrian Friendly Outdoor Lighting

    Energy Technology Data Exchange (ETDEWEB)

    Miller, Naomi J.; Koltai, Rita; McGowan, Terry

    2013-12-31

    This GATEWAY report discusses the problems of pedestrian lighting that occur with all technologies with a focus on the unique optical options and opportunities offered by LEDs through the findings from two pedestrian-focused projects, one at Stanford University in California, and one at the Chautauqua Institution in upstate New York. Incorporating user feedback this report reviews the tradeoffs that must be weighed among visual comfort, color, visibility, efficacy and other factors to stimulate discussion among specifiers, users, energy specialists, and in industry in hopes that new approaches, metrics, and standards can be developed to support pedestrian-focused communities, while reducing energy use.

  8. The closer the relationship, the more the interaction on facebook? Investigating the case of Taiwan users.

    Science.gov (United States)

    Hsu, Chiung-Wen Julia; Wang, Ching-Chan; Tai, Yi-Ting

    2011-01-01

    This study argues for the necessity of applying offline contexts to social networking site research and the importance of distinguishing the relationship types of users' counterparts when studying Facebook users' behaviors. In an attempt to examine the relationship among users' behaviors, their counterparts' relationship types, and the users' perceived acquaintanceships after using Facebook, this study first investigated users' frequently used tools when interacting with different types of friends. Users tended to use less time- and effort-consuming and less privacy-concerned tools with newly acquired friends. This study further examined users' behaviors in terms of their closeness and intimacy and their perceived acquaintanceships toward four different types of friends. The study found that users gained more perceived acquaintanceships from less close friends with whom users have more frequent interaction but less intimate behaviors. As for closer friends, users tended to use more intimate activities to interact with them. However, these activities did not necessarily occur more frequently than the activities they employed with their less close friends. It was found that perceived acquaintanceships with closer friends were significantly lower than those with less close friends. This implies that Facebook is a mechanism for new friends, rather than close friends, to become more acquainted.

  9. Thinking with friends:

    DEFF Research Database (Denmark)

    Emmeche, Claus

    2017-01-01

    Can research in situated and embodied cognition inform the study of interpersonal relations like friendship? And conversely, can friendship studies from disciplinary and interdisciplinary perspectives inspire research in cognitive science? These are the guiding questions for this chapter. Compared...... cognitive phenomenon, and bringing together observations and concepts from interdisciplinary studies of interpersonal relationships allows for a notion of relational attention to be developed. At least for some forms of friendships, the agents not merely attend to common interests; their perception...... is shared, mediated by the very relationship as an embodied activity of distributed cognition. An important example of this is collaboration in science and art, as when friends or colleagues work close together to solve problems or develop new forms of creative expression....

  10. My Nepalese Friends

    Institute of Scientific and Technical Information of China (English)

    1996-01-01

    NEPAL and China are good neighbors. In the 1980s many Chinese technicians went to Nepal to help build roads and other projects. As an interpreter with a Chinese construction cooperative, I worked there from 1993 to 1994. During my stay in Nepal, I met many different Nepalese women who impressed me deeply. My landlady Sumiyala, was the first Nepalese woman to come into my life. She was over 40 years old, a healthy and good-humored housewife. Whenever Ⅰ had time, I liked to chat with her and gradually we became friends. I remember my landlady was busy in and out of her house all day long— cleaning, cooking and taking care of her grandchildren and her parents-in-laws.

  11. Environmentally friendly road construction

    Directory of Open Access Journals (Sweden)

    A.I. Essawy

    2013-06-01

    Full Text Available Environmental pollution is a major problem in developing countries like Egypt. Reuse of waste polymers is considered an attractive solution for environmental white pollution and reducing of the costs of road pavement and maintenance. This research aims to prepare environmentally friendly hot mix asphalt (HMA for paving using some industrial wastes as polypropylene and polyester fibers. The solid materials in the mix include normal and highly porous aggregates. 5% and 10% of waste polymers by weight of the asphalt were used to prepare special binders. The samples were tested for their physical properties, chemical properties, aging, scanning electron microscopy (SEM and thermo-gravimetric analysis (TGA. The results revealed that the prepared HMA using 5% of waste polymer had high performance as compared to the ordinary one and the waste polymer could be used in road construction.

  12. Do Friends Share and Communicate More than Non-Friends?

    Science.gov (United States)

    Sharabany, Ruth; Hertz-Lazarowitz, Rachel

    1981-01-01

    Observed the social communication and task relevant behaviors of 80 kindergarten and first-grade children, each of whom was assigned to do a task with either a friend or a nonfriend. Results showed that friends exhibited less sharing and communicative behaviors and more task relevant behaviors. An explanatory model is suggested to account for…

  13. Solar walls in tsbi3 user`s guide

    Energy Technology Data Exchange (ETDEWEB)

    Wittchen, K.B.

    1997-12-01

    Tsbi3 is a user-friendly and flexible computer program, which provides support to the design team in the analysis of the indoor climate and the energy performance of buildings. The solar wall module gives tsbi3 the capability of simulating solar walls and their interaction with the building. This version, C, of tsbi3 is capable of simulating five types of solar walls say: mass-walls, Trombe-walls, double Trombe-walls, internally ventilated walls and solar walls for preheating ventilation air. The user`s guide gives a description of the capabilities and how to simulate solar walls in tsbi3. (au)

  14. My Good Friend and I

    Institute of Scientific and Technical Information of China (English)

    郑志阳; 罗美珍

    2011-01-01

    I have many friends. But I like Sunny best. He is my good friend. Sunny is ten years old. He has two small eyes. He is thin and tall. He like reading picture books, watching TV, and he also likes playing computergames.

  15. Friends of science

    Science.gov (United States)

    Ten members of Congress have been presented with the Friends of Science Award by the National Coalition for Science and Technology (NCST). The awards, honoring significant contributions to science, engineering, and science education, are made every 2 years at the end of the congressional session. The recipients this year are Sen. Pete V. Domenici (R-N.M.), Rep. Joseph D. Early (D-Mass.), Rep. Bill Frenzel (R-Minn.), Rep. Albert Gore, Jr. (D-Tenn.), Rep. Judd Gregg (R-N.H.), Sen. Daniel K. Inouye (D-Hawaii), Rep. Stan Lundine (D-N.Y.), Sen. Sam Nunn (D-Ga.), Rep. Henry Waxman (D-Calif.), and Rep. Ed Zschau (R-Calif).Except for Sen. Inouye, whose term expires in 1986, all of this year's recipients were up for reelection in the national elections held November 6. All were successful in securing another term in Congress. In addition, Albert Gore was successful in his bid for a Senate seat, filling the vacancy left by the retiring Senate Majority Leader Howard H. Baker (R-Tenn.)

  16. Environmental friendly nitrogen fertilization

    Institute of Scientific and Technical Information of China (English)

    Avi; Shaviv

    2005-01-01

    With the huge intensification of agriculture and the increasing awareness to human health and natural resources sustainability, there was a shift towards the development of environmental friendly N application approaches that support sustainable use of land and sustain food production.The effectiveness of such approaches depends on their ability to synchronize plant nitrogen demand with its supply and the ability to apply favored compositions and dosages of N-species.They are also influenced by farming scale and its sophistication, and include the following key concepts: (i) Improved application modes such as split or localized ("depot") application; (ii) use of bio-amendments like nitrification and urease inhibitors and combinations of (i) and (ii); (iii) use of controlled and slow release fertilizers; (iv) Fertigation-fertilization via irrigation systems including fully automated and controlled systems; and (v) precision fertilization in large scale farming systems. The paper describes the approaches and their action mechanisms and examines their agronomic and environmental significance. The relevance of the approaches for different farming scales, levels of agronomic intensification and agro-technical sophistication is examined as well.

  17. User interface design considerations

    DEFF Research Database (Denmark)

    Andersen, Simon Engedal; Jakobsen, Arne; Rasmussen, Bjarne D.

    1999-01-01

    When designing a user interface for a simulation model there are several important issues to consider: Who is the target user group, and which a priori information can be expected. What questions do the users want answers to and what questions are answered using a specific model?When developing...... the user interface of EESCoolTools these issues led to a series of simulation tools each with a specific purpose and a carefully selected set of input and output variables. To allow a more wide range of questions to be answered by the same model, the user can change between different sets of input...... and output variables. This feature requires special attention when designing the user interface and a special approach for controlling the user selection of input and output variables are developed. To obtain a consistent system description the different input variables are grouped corresponding...

  18. ELEFANT: a user-friendly multipurpose geodynamics code

    Directory of Open Access Journals (Sweden)

    C. Thieulot

    2014-07-01

    Full Text Available A new finite element code for the solution of the Stokes and heat transport equations is presented. It has purposely been designed to address geological flow problems in two and three dimensions at crustal and lithospheric scales. The code relies on the Marker-in-Cell technique and Lagrangian markers are used to track materials in the simulation domain which allows recording of the integrated history of deformation; their (number density is variable and dynamically adapted. A variety of rheologies has been implemented including nonlinear thermally activated dislocation and diffusion creep and brittle (or plastic frictional models. The code is built on the Arbitrary Lagrangian Eulerian kinematic description: the computational grid deforms vertically and allows for a true free surface while the computational domain remains of constant width in the horizontal direction. The solution to the large system of algebraic equations resulting from the finite element discretisation and linearisation of the set of coupled partial differential equations to be solved is obtained by means of the efficient parallel direct solver MUMPS whose performance is thoroughly tested, or by means of the WISMP and AGMG iterative solvers. The code accuracy is assessed by means of many geodynamically relevant benchmark experiments which highlight specific features or algorithms, e.g., the implementation of the free surface stabilisation algorithm, the (visco-plastic rheology implementation, the temperature advection, the capacity of the code to handle large viscosity contrasts. A two-dimensional application to salt tectonics presented as case study illustrates the potential of the code to model large scale high resolution thermo-mechanically coupled free surface flows.

  19. 10 Web Tools to Create User-Friendly Sites

    Science.gov (United States)

    Pretlow, Cassi

    2008-01-01

    Surprisingly, many tools exist on the web that can help sites become more inviting and easier to use. By now, many are probably familiar with the free tools offered by Flickr, del.icio.us, or YouTube for embedding images, tags, and videos on webpages. This article presents a comprehensive list of some perhaps lesser-known but equally useful tools…

  20. A user-friendly web content management system for scouts

    OpenAIRE

    Štrajhar, Andrej

    2012-01-01

    The work describes content managment systems, their advantages and disadvantages. I described the three most commonly used systems: WordPress, Drupal and Joomla. These systems were comparedThe main part of the work is the description of the content management system SkavtČAROVNIK, which was developed in 2010 and 2011 by the SkavtNET team. I have described the functionalities and technologies used for application development and implementation of comments. Implementation of the comments is ...

  1. RADIATION PROTECTION OF LINAC BUNKERS. A USER-FRIENDLY APPROACH

    DEFF Research Database (Denmark)

    Holten Sørensen, Thyge; Olsen, Kjeld Jørgen; Behrens, Claus Flensted

    2015-01-01

    A well-known but complex formalism for the calculation of the leakage dose at the entrance of the linac maze was considered and simplified. These simplifications were based partly on the literature and partly on the authors' own measurements. The authors have included photon scatter originating f...... from the irradiated patient in the formalism. A formalism for two different types of bunkers was developed, and the authors have obtained simple formulas to calculate the dose at the maze entrance for both bunker types....

  2. A User-Friendly Code to Diagnose Chromospheric Plasmas

    OpenAIRE

    2007-01-01

    The physical interpretation of spectropolarimetric observations of lines of neutral helium, such as those of the 10830 A multiplet, represents an excellent opportunity for investigating the magnetism of plasma structures in the solar chromosphere. Here we present a powerful forward modeling and inversion code that permits either to calculate the emergent intensity and polarization for any given magnetic field vector or to infer the dynamical and magnetic properties from the observed Stokes pr...

  3. GMOseek: a user friendly tool for optimized GMO testing

    OpenAIRE

    Morisset, Dany; Novak, Petra Kralj; Zupanič, Darko; Gruden, Kristina; Lavrač, Nada; Žel, Jana

    2014-01-01

    Background With the increasing pace of new Genetically Modified Organisms (GMOs) authorized or in pipeline for commercialization worldwide, the task of the laboratories in charge to test the compliance of food, feed or seed samples with their relevant regulations became difficult and costly. Many of them have already adopted the so called "matrix approach" to rationalize the resources and efforts used to increase their efficiency within a limited budget. Most of the time, the "matrix approach...

  4. GMOseek: a user friendly tool for optimized GMO testing

    National Research Council Canada - National Science Library

    Morisset, Dany; Novak, Petra Kralj; Zupanič, Darko; Gruden, Kristina; Lavrač, Nada; Žel, Jana

    2014-01-01

    ...) computational tool to efficiently use the available data. The developed GMOseek software is designed to support decision making in all the phases of routine GMO laboratory testing, including the interpretation...

  5. A User-Friendly Method for Teaching Restriction Enzyme Mapping.

    Science.gov (United States)

    Ehrman, Patrick

    1990-01-01

    Presented is a teaching progression that enhances learning through low-cost, manipulative transparencies. Discussed is instruction about restriction enzymes, plasmids, cutting plasmids, plasmid maps, recording data, and mapping restriction sites. Mapping wheels for student use is included. (CW)

  6. Tougher: A user-friendly graphical interface for TOUGHREACT

    Science.gov (United States)

    Li, You; Niewiadomski, Marcin; Trujillo, Edward; Sunkavalli, Surya Prakash

    2011-06-01

    TOUGHREACT is a powerful simulator for multiphase fluid, heat, and chemical transport, but has a steep learning curve and the creation of the input files is time intensive, particularly for heterogeneous and complex geometries such as those in mining rock pile formations. TOUGHER is an application developed by the acid rock drainage research group of the Department of Chemical Engineering at the University of Utah in order to develop TOUGHREACT models rapidly for two-dimensional problems and to be able to visualize the simulation results in an intuitive way. It also reduces errors when creating complex layered 2D models and makes debugging easier. The software is currently limited to 2D rectangular grids with constant spatial sizes. The application is written in C++ and can be used on any computer with a Windows or Linux operating system. This paper will describe the overall structure of the application and give some examples of how it interfaces with the TOUGHREACT program. In particular, it will be shown how the application can generate a grid system for a rock pile containing several distinct geological layers, how the properties of each layer are set, and how the input sections (ELEM and CONNE) for TOUGHREACT are generated automatically. In addition, visualizing the flow and chemical output files generated by TOUGHREACT for a particular rock pile will be demonstrated. This includes transient vector as well as transient scalar data. At the end of the paper, two case studies, one with a simplified geometry and another with more complex layered rock geometry, will be presented.

  7. FEWDATA--A User-Friendly Viewdata System.

    Science.gov (United States)

    Fallon, Graham; Jones, Catherine

    1988-01-01

    Describes FEWDATA, a Welsh viewdata system serving colleges and schools throughout Wales. Discusses how to use the system and examines its features, including (1) on-screen tutorials and systems update; (2) existing data screens; (3) information screens on education in Wales; and (4) data concerning Welsh counties and elections. (GEA)

  8. A "User-Friendly" Program for Vapor-Liquid Equilibrium.

    Science.gov (United States)

    Da Silva, Francisco A.; And Others

    1991-01-01

    Described is a computer software package suitable for teaching and research in the area of multicomponent vapor-liquid equilibrium. This program, which has a complete database, can accomplish phase-equilibrium calculations using various models and graph the results. (KR)

  9. The User-friendly On-Line Diffusion Chamber

    CERN Document Server

    Aviles Acosta, Jaime

    2015-01-01

    The On-Line Diffusion Chamber is a stand-alone apparatus built to carry out short-live radiotracer diffusion studies. The availability of the on-demand production of isotopes in the ISOLDE facility, and the design of the apparatus to streamline the implantation process, annealing treatment, ion gun ablation with a tape transport system, and radiation intensity measurement with a Ge gamma detector all in the same apparatus, gives the On-Line Diffusion Chamber a unique ability to studies with short-lived radioisotopes or isomer states that are not possible in any other facility in the world.

  10. A User-Friendly Code to Diagnose Chromospheric Plasmas

    CERN Document Server

    Ramos, A Asensio

    2007-01-01

    The physical interpretation of spectropolarimetric observations of lines of neutral helium, such as those of the 10830 A multiplet, represents an excellent opportunity for investigating the magnetism of plasma structures in the solar chromosphere. Here we present a powerful forward modeling and inversion code that permits either to calculate the emergent intensity and polarization for any given magnetic field vector or to infer the dynamical and magnetic properties from the observed Stokes profiles. This diagnostic tool is based on the quantum theory of spectral line polarization, which self-consistently accounts for the Hanle and Zeeman effects in the most general case of the incomplete Paschen-Back effect regime. We also take into account radiative transfer effects. An efficient numerical scheme based on global optimization methods has been applied. Our Stokes inversion code permits a fast and reliable determination of the global minimum.

  11. A User-Friendly Code to Diagnose Chromospheric Plasmas

    Science.gov (United States)

    Asensio Ramos, A.; Trujillo Bueno, J.

    2007-05-01

    The physical interpretation of spectropolarimetric observations of lines of neutral helium, such as those of the 10830 Å multiplet, represents an excellent opportunity for investigating the magnetism of plasma structures in the solar chromosphere. Here we present a powerful forward modeling and inversion code that permits either to calculate the emergent intensity and polarization for any given magnetic field vector or to infer the dynamical and magnetic properties from the observed Stokes profiles. This diagnostic tool is based on the quantum theory of spectral line polarization, which self-consistently accounts for the Hanle and Zeeman effects in the most general case of the incomplete Paschen-Back effect regime. We also take into account radiative transfer effects. An efficient numerical scheme based on global optimization methods has been applied. Our Stokes inversion code permits a fast and reliable determination of the global minimum.

  12. User-friendly Tool for Power Flow Analysis and Distributed ...

    African Journals Online (AJOL)

    Akorede

    an efficient and reliable manner – with minimal energy loss cost. ... recent renewed global interest in DG since the conventional ... 1Department of Electrical & Electronic Engineering, Universiti Putra Malaysia, ... in increase in the power frequency beyond the preset upper ...... New Jersey, USA, Pearson Education, Inc.,.

  13. User-Friendly Tools for Random Matrices: An Introduction

    Science.gov (United States)

    2012-12-03

    The set of positive-semidefinite matrices with size d forms a closed, convex cone in the real- linear space of Hermitian matrices of dimension d...valued function h on matrices that is concave or convex. The expectation of a random matrix can be viewed as a convex combination, and the cone of...hope shatters when we subject it to interrogation. It is not hard to find the reason that (3.3.2) fails. Note that the identity (3.3.1) depends on the

  14. Latex and friends

    CERN Document Server

    Dongen, M R C van

    2012-01-01

    LaTeX is a free, automated state-of-the-art typesetting system. This book teaches all the ins and outs of LaTeX which are needed to write an article, report, thesis, or book. The book teaches by example, giving many worked out examples showing input and output side by side. The book presents the most recent techniques for presenting data plots, complex graphics, and computer presentations, but does not require previous knowledge. However, it is also a reference for the more seasoned user, with pointers to modern techniques and packages. Recurring themes in the book are consistent and effective

  15. Environmentally-friendly practices in hotels

    Directory of Open Access Journals (Sweden)

    Miriam Mbasera

    2016-03-01

    Full Text Available Orientation: There has been a growing concern for a ‘green’ hotel in the view of customers as they experience an increased awareness of environmental damage and excessive consumption of goods, energy and water.Research purpose: To determine the environmentally-friendly practices in hotels in Zimbabwe and South Africa and establish the contribution that hotels are making towards mitigation of the negative environmental effects.Motivation for the study: Currently, the world is facing environmental issues, which include global climate change, ozone depletion, pollution, high consumption of resources and increasing amounts of solid waste. Hotels, as part of the tourism industry, exert a significant impact on the environment. While the extent and range of the impact that hotels exert on the environment suggest an urgent need to address this problem, the question that arises is whether hoteliers appreciate the need for environmentally-friendly initiatives in their establishments.Research design, approach and method: A qualitative research was carried out in eight hotels that employ the strategy of the case study in the aforementioned countries. Main findings: Currently, no policies for green management exist, although some hotels do engage in some environmentally-friendly practices. Some hotel managers do not implement green management initiatives to mitigate the environmental problems emanating from their hotel operations.Practical and/or managerial implications: This indicates that a gap exists between managers’ awareness of appropriate environmentally-friendly practices for hotels, implying a need for training and increased awareness of green management.Contribution and/or value-add: The results could guide managers in the implementation of environmentally-friendly practices in an effort to mitigate environmental problems facing the present generation.

  16. Learning from Your Network of Friends: A Trajectory Representation Learning Model Based on Online Social Ties

    KAUST Repository

    Alharbi, Basma Mohammed

    2017-02-07

    Location-Based Social Networks (LBSNs) capture individuals whereabouts for a large portion of the population. To utilize this data for user (location)-similarity based tasks, one must map the raw data into a low-dimensional uniform feature space. However, due to the nature of LBSNs, many users have sparse and incomplete check-ins. In this work, we propose to overcome this issue by leveraging the network of friends, when learning the new feature space. We first analyze the impact of friends on individuals\\'s mobility, and show that individuals trajectories are correlated with thoseof their friends and friends of friends (2-hop friends) in an online setting. Based on our observation, we propose a mixed-membership model that infers global mobility patterns from users\\' check-ins and their network of friends, without impairing the model\\'s complexity. Our proposed model infers global patterns and learns new representations for both usersand locations simultaneously. We evaluate the inferred patterns and compare the quality of the new user representation against baseline methods on a social link prediction problem.

  17. Exploring User Navigation during Online Health Information Seeking

    OpenAIRE

    Graham, Laurel; Tse, Tony; Keselman, Alla

    2006-01-01

    Understanding online user behavior is essential for designing user-friendly consumer health Web sites. Transaction log analysis (TLA) provides a way to extract aggregate data about online behavior. This paper describes prevalent user navigation trends using TLA methods at ClinicalTrials.gov. Preliminary results suggest that users typically access low-level pages directly from Web-based search engines and consumer health sites/portals. A pilot user study is presented to illustrate a complement...

  18. User 2020

    DEFF Research Database (Denmark)

    Porras, Jari; Heikkinen, Kari; Kinnula, Marianne

    2014-01-01

    and environment, and each has had its effect on the development of technology. The closer we come to the current generation, the bigger is the effect of technology on the characteristics of that generation. User needs guide the technology and the technology shapes the users. This WWRF Outlook analyses......The User 2020 vision is of the changing needs and habits of a user in the future digital world. In order to understand the needs of the future users, we need to look at how users and technology have changed during recent years. The different generations of users are products of their own time...... determined by the era in which they were born. This is due to the fact that digital natives, born in an already “fully” digitalized world with a plethora of ICT services, have a much closer relationship to these solutions than generations before them. This has also shaped the users perspectives and had...

  19. Understanding users

    DEFF Research Database (Denmark)

    Johannsen, Carl Gustav Viggo

    2014-01-01

    Segmentation of users can help libraries in the process of understanding user similarities and differences. Segmentation can also form the basis for selecting segments of target users and for developing tailored services for specific target segments. Several approaches and techniques have been...... segmentation project using computer-generated clusters. Compared to traditional marketing texts, this article also tries to identify user segments or images or metaphors by the library profession itself....

  20. Understanding users

    DEFF Research Database (Denmark)

    Johannsen, Carl Gustav Viggo

    2014-01-01

    Segmentation of users can help libraries in the process of understanding user similarities and differences. Segmentation can also form the basis for selecting segments of target users and for developing tailored services for specific target segments. Several approaches and techniques have been te...... segmentation project using computer-generated clusters. Compared to traditional marketing texts, this article also tries to identify user segments or images or metaphors by the library profession itself....

  1. The patient-friendly practice.

    Science.gov (United States)

    Dooley, Sharon Kay

    2006-01-01

    In today's medical marketplace, patients see themselves as consumers of healthcare with certain customer-service expectations. The medical practice that is indifferent or resistant to these changes is at risk. Having a good understanding of patient-friendly changes can help a practice survive in a changing environment. A patient-friendly office will continue to meet the needs of the patient by adopting this new practice style.

  2. Web-Based Family Life Education: Spotlight on User Experience

    Science.gov (United States)

    Doty, Jennifer; Doty, Matthew; Dwrokin, Jodi

    2011-01-01

    Family Life Education (FLE) websites can benefit from the field of user experience, which makes technology easy to use. A heuristic evaluation of five FLE sites was performed using Neilson's heuristics, guidelines for making sites user friendly. Greater site complexity resulted in more potential user problems. Sites most frequently had problems…

  3. Web-Based Family Life Education: Spotlight on User Experience

    Science.gov (United States)

    Doty, Jennifer; Doty, Matthew; Dwrokin, Jodi

    2011-01-01

    Family Life Education (FLE) websites can benefit from the field of user experience, which makes technology easy to use. A heuristic evaluation of five FLE sites was performed using Neilson's heuristics, guidelines for making sites user friendly. Greater site complexity resulted in more potential user problems. Sites most frequently had problems…

  4. Comparing Text-based and Graphic User Interfaces for novice and expert users.

    Science.gov (United States)

    Chen, Jung-Wei; Zhang, Jiajie

    2007-10-11

    Graphic User Interface (GUI) is commonly considered to be superior to Text-based User Interface (TUI). This study compares GUI and TUI in an electronic dental record system. Several usability analysis techniques compared the relative effectiveness of a GUI and a TUI. Expert users and novice users were evaluated in time required and steps needed to complete the task. A within-subject design was used to evaluate if the experience with either interface will affect task performance. The results show that the GUI interface was not better than the TUI for expert users. GUI interface was better for novice users. For novice users there was a learning transfer effect from TUI to GUI. This means a user interface is user-friendly or not depending on the mapping between the user interface and tasks. GUI by itself may or may not be better than TUI.

  5. DIRAC: Secure web user interface

    Energy Technology Data Exchange (ETDEWEB)

    Casajus Ramo, A [University of Barcelona, Diagonal 647, ES-08028 Barcelona (Spain); Sapunov, M, E-mail: sapunov@in2p3.f [Centre de Physique des Particules de Marseille, 163 Av de Luminy Case 902 13288 Marseille (France)

    2010-04-01

    Traditionally the interaction between users and the Grid is done with command line tools. However, these tools are difficult to use by non-expert users providing minimal help and generating outputs not always easy to understand especially in case of errors. Graphical User Interfaces are typically limited to providing access to the monitoring or accounting information and concentrate on some particular aspects failing to cover the full spectrum of grid control tasks. To make the Grid more user friendly more complete graphical interfaces are needed. Within the DIRAC project we have attempted to construct a Web based User Interface that provides means not only for monitoring the system behavior but also allows to steer the main user activities on the grid. Using DIRAC's web interface a user can easily track jobs and data. It provides access to job information and allows performing actions on jobs such as killing or deleting. Data managers can define and monitor file transfer activity as well as check requests set by jobs. Production managers can define and follow large data productions and react if necessary by stopping or starting them. The Web Portal is build following all the grid security standards and using modern Web 2.0 technologies which allow to achieve the user experience similar to the desktop applications. Details of the DIRAC Web Portal architecture and User Interface will be presented and discussed.

  6. Multi-Output Recommender: Items, Groups and Friends, and Their Mutual Contributing Effects

    CERN Document Server

    Zeng, Wei

    2012-01-01

    Up to now, more and more online sites have started to allow their users to build the social relationships. Take the Last.fm for example, users could not only add each other as friends, but also join interest groups that include people with common tastes. Therefore, in this environment, users might be interested in not only receiving item recommendations, but also getting suggestion of friends whom they might put in the contact list, and recommendation of interest groups that they could consider to join. To support such needs, in this paper, we propose a generalized framework that provides three different types of recommendation in a single system: recommending items, recommending groups and recommending friends. For each type of recommendation, we in depth investigate the respective roles of other two information resources (e.g., user-item preferences and friendship for recommending groups), along with their combined effect. The experiment reveals the ideal fusion mechanism for the multi-output recommendation...

  7. Testing of environmentally friendly lubricants for sheet metal forming

    DEFF Research Database (Denmark)

    Bay, Niels; Olsson, David Dam; Andreasen, Jan Lasson

    2005-01-01

    the authors have especially been involved in the development of a system of test methods for sheet metal forming and in testing of friction and limits of lubrication of new, environmentally friendly lubricants. An overview of the developed tests is presented together with selected results....... Kingdom, Finland, Poland, Slovenia, Spain and Denmark. Partners in the programmes represent lubricant developers, testing experts and industrial end users as well as numerical modelling experts simulating fundamental lubrication mechanisms and computing basic process parameters. In these programmes...

  8. Mobile Tracking Application for Locating Friends using LBS

    Directory of Open Access Journals (Sweden)

    R.K.Nadesh,

    2011-06-01

    Full Text Available Now-a-days Location based services are becoming more important to mobile users. LBS are the mobile service which uses the user location information which consists of X and Y coordinates generated by GPS which is a mostly used positioning technique. This paper presents a mobile location tracking application in a cellular mobile networkbased on Location based service that describes tracking system called mobile tracker using GPS as a location provider through the geographic positions of a mobile network. This implements a client server system that helps the users to locate their friends and receive alerts whenever they are nearby. It enables the user, basing on the radius around the mobile device defined by the administrator. MYSQL database is used to update the location information and track the location. Further enhancement can be done by increasing the radius capacity to communicate more deliberately.

  9. User design

    CERN Document Server

    Carr-Chellman, Alison A

    2012-01-01

    User Design offers a fresh perspective on how front-line learners (users) can participate in the design of learning environments. The author challenges the universal assumption that front-line users must be relegated to the role of offering input, and that the actual design activity of learning systems must still be conducted only by experts. The book presents a new set of methods and strategies that show how the tools of professional designers can be effectively shared with broad groups of users and other participants in the process of creating their own learning. Drawing

  10. An Invitation to Friendly Testing

    Institute of Scientific and Technical Information of China (English)

    DaviddeFrutos-Escring; LuisLlana-Diaz; 等

    1998-01-01

    We present a new testing semantics,called friendly testing,whose main property is that the induced preorder between processes Contain in fr is consistent with the conformance relation,and so we have,for instance,a+b Contain in fr a Contain in fr a+b .The new theory is strongly based on De Nicola & Hennessy's work on testing.Friendly tests are defined exactly as in their work,except that internal actions are not allowed.However,in order to obtain the desired notion of friendly testing this restriction is not enough and we also have to relax the conditions to pass a test. Thus we obtain a new testing semantics and a new preorder between processes which is strictly weaker than the relation Contain in must.Moreover,we present an altrnative characterization of our new testing semantics by defining a modification of acceptance sets.

  11. "Friends" Raping Friends. Could It Happen to You?

    Science.gov (United States)

    Hughes, Jean O'Gorman; Sandler, Bernice R.

    This publication concerning rape committed by acquaintances and "friends" is designed to provide information and support for college students. The early warning signs and how to react to potential "acquaintance" or "date" rape are addressed. Consideration is given to why this type of rape occurs and information is provided on how to avoid date…

  12. Our Brain Enjoys Making Friends

    OpenAIRE

    Gleichgerrcht, Ezequiel; Salvarezza, Florencia; Manes, Facundo

    2013-01-01

    Is it important to have friends? Why do we enjoy spending time with them? Do we learn differently around our friends? Neuroscience research is helping us to answer some of these questions by looking at the way our brain allows us to, and benefits from, interacting with other humans. Part of the reason why human brains are so complex is that our interactions with others are so complex; we are social creatures and have been living in groups for thousands of years. Our brain has developed the ab...

  13. User-centric networking future perspectives

    CERN Document Server

    Aldini, Alessandro

    2014-01-01

    This work represents a milestone for the? 'ULOOP User-centric Wireless Local Loop' project funded by the EU IST Seventh Framework Programme.ULOOP is focused on the robust, secure, and autonomic deployment of user-centric wireless networks. Contributions by ULOOP partners as well as invited tutorials by international experts in the field. The expected impact is to increase awareness to user-centric networking in terms, e.g., of business opportunities and quality of experience, and to present adequate technology to sustain the growth of user-friendly wireless architectures.Throughout the last 3

  14. You Don't De-Friend the Dead: An Analysis of Grief Communication by College Students through Facebook Profiles

    Science.gov (United States)

    Pennington, Natalie

    2013-01-01

    This research examined how various members of a social network interact with the Facebook (FB) profile page of a friend who has died. From 43 in-depth qualitative interviews, FB friends of deceased FB users maintained their FB connection with the deceased. Most participants who visited the profile found it helpful to look at pictures; a few wrote…

  15. Adolescent friend similarity on alcohol abuse as a function of participation in romantic relationships: Sometimes a new love comes between old friends.

    Science.gov (United States)

    DeLay, Dawn; Laursen, Brett; Bukowski, William M; Kerr, Margaret; Stattin, Håkan

    2016-01-01

    This study tests the hypothesis that adolescents with romantic partners are less similar to their friends on rates of alcohol abuse than adolescents without romantic partners. Participants (662 girls, 574 boys) ranging in age from 12 to 19 years nominated friends and romantic partners, and completed a measure of alcohol abuse. In hierarchical linear models, friends with romantic partners were less similar on rates of alcohol abuse than friends without romantic partners, especially if they were older and less accepted. Follow-up longitudinal analyses were conducted on a subsample (266 boys, 374 girls) of adolescents who reported friendships that were stable across 2 consecutive years. Associations between friend reports of alcohol abuse declined after adolescents became involved in a romantic relationship, to the point at which they became more similar to their romantic partners than to their friends. (PsycINFO Database Record

  16. Free Our Friends in Learning

    Science.gov (United States)

    Stidham, Sue

    2007-01-01

    Many secrets can be told by the physical surroundings of library media centers. Whether the center is kid-friendly is one of the first obvious tell-tale signs. When a library center has Arthur & D.W., Clifford, Pooh & Eeyore, shells, special rocks, etc. hidden by the circulation center or in the back in boxes, it's time to revolt. The movie Free…

  17. My stepfather,My friend

    Institute of Scientific and Technical Information of China (English)

    杨武

    2005-01-01

    Nine years ago, after Leo had died, people said to me, ""I never knew he was your stepfa-ther."" You see, I never called .him that. At first, he was no one special in my life. Then he became my friend. In time, I felt he was my fa-ther too.

  18. Adolescent Friend Similarity on Alcohol Abuse as a Function of Participation in Romantic Relationships: Sometimes a New Love Comes between Old Friends

    Science.gov (United States)

    DeLay, Dawn; Laursen, Brett; Bukowski, William M.; Kerr, Margaret; Stattin, Håkan

    2016-01-01

    This study tests the hypothesis that adolescents with romantic partners are less similar to their friends on rates of alcohol abuse than adolescents without romantic partners. Participants (662 girls, 574 boys) ranging in age from 12 to 19 years nominated friends and romantic partners, and completed a measure of alcohol abuse. In hierarchical…

  19. Adolescent Friend Similarity on Alcohol Abuse as a Function of Participation in Romantic Relationships: Sometimes a New Love Comes between Old Friends

    Science.gov (United States)

    DeLay, Dawn; Laursen, Brett; Bukowski, William M.; Kerr, Margaret; Stattin, Håkan

    2016-01-01

    This study tests the hypothesis that adolescents with romantic partners are less similar to their friends on rates of alcohol abuse than adolescents without romantic partners. Participants (662 girls, 574 boys) ranging in age from 12 to 19 years nominated friends and romantic partners, and completed a measure of alcohol abuse. In hierarchical…

  20. Game user experience evaluation

    CERN Document Server

    Bernhaupt, Regina

    2015-01-01

    Evaluating interactive systems for their user experience (UX) is a standard approach in industry and research today. This book explores the areas of game design and development and Human Computer Interaction (HCI) as ways to understand the various contributing aspects of the overall gaming experience. Fully updated, extended and revised this book is based upon the original publication Evaluating User Experience in Games, and provides updated methods and approaches ranging from user- orientated methods to game specific approaches. New and emerging methods and areas explored include physiologi

  1. Intermediate peer contexts and educational outcomes: Do the friends of students' friends matter?

    Science.gov (United States)

    Carbonaro, William; Workman, Joseph

    2016-07-01

    Sociologists of education have long been interested in the effects of peer relations on educational outcomes. Recent theory and research on adolescence suggest that peers on the boundaries of students' friendship networks may play an important role in shaping behaviors and educational outcomes. In this study, we examine the importance of a key "intermediate peer context" for students' outcomes: the friends of a student's friends. Our findings indicate both friends' and friends' friends' characteristics independently predict students' college expectations and their risk of dropping out of high school (although only friends' characteristics predict GPA). Our models suggest the magnitude of students' friends-of-friends' characteristics are at least as large their friends' characteristics. Together, the association between the peer context and students outcomes is considerably larger when accounting for both the characteristics of students' friends and the friends of their friends.

  2. A user friendly spreadsheet program for calibration using weighted regression. User's Guide

    NARCIS (Netherlands)

    Gort SM; Hoogerbrugge R; LOC

    1995-01-01

    Een gebruiksvriendelijke computer spreadsheet voor calibratie doeleinden is beschreven. Deze spreadsheet (ontwikkeld met behulp van Microsoft Excel) stelt niet-statistici, zoals analytische chemici, in de gelegenheid om gewogen lineaire regressie toe te passen. Verschillende calibratiefuncties en

  3. Solar walls in tsbi3 user's guide

    DEFF Research Database (Denmark)

    Wittchen, K.B.

    tsbi3 is a user-friendly and flexible computer program, which provides support to the design team in the analysis of the indoor climate and the energy performance of buildings. The solar wall module gives tsbi3 the capability of simulating solar walls and their interaction with the building. This...

  4. Microbiota, immunoregulatory old friends and psychiatric disorders.

    Science.gov (United States)

    Rook, Graham A W; Raison, Charles L; Lowry, Christopher A

    2014-01-01

    Regulation of the immune system is an important function of the gut microbiota. Increasing evidence suggests that modern living conditions cause the gut microbiota to deviate from the form it took during human evolution. Contributing factors include loss of helminth infections, encountering less microbial biodiversity, and modulation of the microbiota composition by diet and antibiotic use. Thus the gut microbiota is a major mediator of the hygiene hypothesis (or as we prefer, "Old Friends" mechanism), which describes the role of organisms with which we co-evolved, and that needed to be tolerated, as crucial inducers of immunoregulation. At least partly as a consequence of reduced exposure to immunoregulatory Old Friends, many but not all of which resided in the gut, high-income countries are undergoing large increases in a wide range of chronic inflammatory disorders including allergies, autoimmunity and inflammatory bowel diseases. Depression, anxiety and reduced stress resilience are comorbid with these conditions, or can occur in individuals with persistently raised circulating levels of biomarkers of inflammation in the absence of clinically apparent peripheral inflammatory disease. Moreover poorly regulated inflammation during pregnancy might contribute to brain developmental abnormalities that underlie some cases of autism spectrum disorders and schizophrenia. In this chapter we explain how the gut microbiota drives immunoregulation, how faulty immunoregulation and inflammation predispose to psychiatric disease, and how psychological stress drives further inflammation via pathways that involve the gut and microbiota. We also outline how this two-way relationship between the brain and inflammation implicates the microbiota, Old Friends and immunoregulation in the control of stress resilience.

  5. Jobs and Economic Development Impact (JEDI) Model Geothermal User Reference Guide

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, C.; Augustine, C.; Goldberg, M.

    2012-09-01

    The Geothermal Jobs and Economic Development Impact (JEDI) model, developed through the National Renewable Energy Laboratory (NREL), is an Excel-based user-friendly tools that estimates the economic impacts of constructing and operating hydrothermal and Enhanced Geothermal System (EGS) power generation projects at the local level for a range of conventional and renewable energy technologies. The JEDI Model Geothermal User Reference Guide was developed to assist users in using and understanding the model. This guide provides information on the model's underlying methodology, as well as the parameters and references used to develop the cost data utilized in the model. This guide also provides basic instruction on model add-in features, operation of the model, and a discussion of how the results should be interpreted.

  6. Friends of the National Library of Medicine

    Science.gov (United States)

    Skip Navigation Bar Home Current Issue Past Issues Friends of the National Library of Medicine Past Issues / ... Javascript on. The Hon. Paul G. Rogers Chairman, Friends of the National Library of Medicine and former ...

  7. Organic and Other Environmentally Friendly Foods

    Science.gov (United States)

    ... Loss Surgery? A Week of Healthy Breakfasts Shyness Organic and Other Environmentally Friendly Foods KidsHealth > For Teens > ... in organic and other environmentally friendly foods. Defining "Organic" If a food is labeled "organic," what does ...

  8. Making Friends While Making Deals

    Institute of Scientific and Technical Information of China (English)

    LII; HAIBO

    2006-01-01

    The China-U.S. relationship is one of the most important bilateral relationships in the world today, and the trade and economic ties between the two countries constitute the most essential part of that relationship. We believe that the China-U.S. relationship is by and large a friendly one, a fact that is ignored or denied by some observers. There are two supporting points here. First, as trade expands and

  9. Genetic Algorithm and Graph Theory Based Matrix Factorization Method for Online Friend Recommendation

    Directory of Open Access Journals (Sweden)

    Qu Li

    2014-01-01

    Full Text Available Online friend recommendation is a fast developing topic in web mining. In this paper, we used SVD matrix factorization to model user and item feature vector and used stochastic gradient descent to amend parameter and improve accuracy. To tackle cold start problem and data sparsity, we used KNN model to influence user feature vector. At the same time, we used graph theory to partition communities with fairly low time and space complexity. What is more, matrix factorization can combine online and offline recommendation. Experiments showed that the hybrid recommendation algorithm is able to recommend online friends with good accuracy.

  10. Be Safe with Your Internet Friends

    Institute of Scientific and Technical Information of China (English)

    康海燕

    2006-01-01

    You can have lots of friends on the Internet.But you must pay attention to your safety. 1.Do not tell your Internet friends your real name,address,phone number, ID card number and so on. 2.Do not send your photos to your Internet friends.

  11. How Friends Influence Adolescents' Adjustment to School.

    Science.gov (United States)

    Berndt, Thomas J.; Keefe, Keunho

    A short-term longitudinal study investigated theoretical perspectives on friends' influences and compared the influence of a student's closest friend with that of several close friends. Participants were 297 seventh and eighth graders in junior high schools in small towns or rural areas adjacent to a medium-sized city. Measures obtained in the…

  12. Convergent spray process for environmentally friendly coatings

    Science.gov (United States)

    Scarpa, Jack

    1995-01-01

    Conventional spray application processes have poor transfer efficiencies, resulting in an exorbitant loss in materials, solvents, and time. Also, with ever tightening Environmental Protection Agency (EPA) regulations and Occupational Safety and Health Administration requirements, the low transfer efficiencies have a significant impact on the quantities of materials and solvents that are released into the environment. High solids spray processes are also limited by material viscosities, thus requiring many passes over the surface to achieve a thickness in the 0.125 -inch range. This results in high application costs and a negative impact on the environment. Until recently, requirements for a 100 percent solid sprayable, environmentally friendly, lightweight thermal protection system that can be applied in a thick (greater than 0.125 inch) single-pass operation exceeded the capability of existing systems. Such coatings must be applied by hand lay-up techniques, especially for thermal and/or fire protection systems. The current formulation of these coatings has presented many problems such as worker safety, environmental hazards, waste, high cost, and application constraints. A system which can apply coatings without using hazardous materials would alleviate many of these problems. Potential applications include the aerospace thermal protective specialty coatings, chemical and petroleum industries that require fire-protection coatings that resist impact, chemicals, and weather. These markets can be penetrated by offering customized coatings applied by automated processes that are environmentally friendly.

  13. Adolescent Boys' Intentions of Seeking Help from Male Friends and Female Friends

    Science.gov (United States)

    Sears, Heather A.; Graham, Joanna; Campbell, Anna

    2009-01-01

    This study examined adolescent boys' intentions of seeking help from male friends and female friends. We evaluated mean differences in boys' help-seeking intentions; assessed whether boys' individual characteristics predicted their intentions; and examined perceived support from male friends and female friends as mediators of these relationships.…

  14. Classroom Friends and Very Best Friends: A Short-Term Longitudinal Analysis of Relationship Quality

    Science.gov (United States)

    McChristian, Chrystal L.; Ray, Glen E.; Tidwell, Pamela S.; LoBello, Steven G.

    2012-01-01

    Second-, third-, fifth-, and sixth-grade children evaluated relationship qualities of a self-nominated friend and a self-nominated very best friend over a 6-month school year period. Results demonstrated that 76% of the friend relationships and 50% of the very best friend relationships were maintained over the course of the study. Children in…

  15. A fast algorithm for identifying Friends-of-Friends halos

    CERN Document Server

    Feng, Yu

    2016-01-01

    We describe a simple and fast algorithm for identifying friends-of-friends clusters and prove its correctness. The algorithm avoids unnecessary expensive neighbor queries, uses minimal memory overhead, and rejects slowdown in high over-density regions. We define our algorithm formally based on pair enumeration, a problem that has been heavily studied in fast 2-point correlation codes and our reference implementation employs a dual KD-tree correlation function code. We construct halos in a hierarchical merger tree, and use a splay operation to reduce the average cost of identifying the root of a cluster from $O[\\log L]$ to $O[1]$ ($L$ is the size of a cluster) without additional memory costs. This reduces the overall time complexity of merging trees form $O[L\\log L]$ to $O[L]$, reducing the number of operations per by orders of magnitude. We next introduce a pruning operation that skips pair enumeration between two fully self-connected KD-tree nodes. This improves the robustness of the algorithm, reducing cost...

  16. Friendly-Sharing: Improving the Performance of City Sensoring through Contact-Based Messaging Applications.

    Science.gov (United States)

    Herrera-Tapia, Jorge; Hernández-Orallo, Enrique; Tomás, Andrés; Manzoni, Pietro; Tavares Calafate, Carlos; Cano, Juan-Carlos

    2016-09-18

    Regular citizens equipped with smart devices are being increasingly used as "sensors" by Smart Cities applications. Using contacts among users, data in the form of messages is obtained and shared. Contact-based messaging applications are based on establishing a short-range communication directly between mobile devices, and on storing the messages in these devices for subsequent delivery to cloud-based services. An effective way to increase the number of messages that can be shared is to increase the contact duration. We thus introduce the Friendly-Sharing diffusion approach, where, during a contact, the users are aware of the time needed to interchange the messages stored in their buffers, and they can thus decide to wait more time in order to increase the message sharing probability. The performance of this approach is anyway closely related to the size of the buffer in the device. We therefore compare various policies either for the message selection at forwarding times and for message dropping when the buffer is full. We evaluate our proposal with a modified version of the Opportunistic Networking Environment (ONE) simulator and using real human mobility traces.

  17. Friendly-Sharing: Improving the Performance of City Sensoring through Contact-Based Messaging Applications

    Directory of Open Access Journals (Sweden)

    Jorge Herrera-Tapia

    2016-09-01

    Full Text Available Regular citizens equipped with smart devices are being increasingly used as “sensors” by Smart Cities applications. Using contacts among users, data in the form of messages is obtained and shared. Contact-based messaging applications are based on establishing a short-range communication directly between mobile devices, and on storing the messages in these devices for subsequent delivery to cloud-based services. An effective way to increase the number of messages that can be shared is to increase the contact duration. We thus introduce the Friendly-Sharing diffusion approach, where, during a contact, the users are aware of the time needed to interchange the messages stored in their buffers, and they can thus decide to wait more time in order to increase the message sharing probability. The performance of this approach is anyway closely related to the size of the buffer in the device. We therefore compare various policies either for the message selection at forwarding times and for message dropping when the buffer is full. We evaluate our proposal with a modified version of the Opportunistic Networking Environment (ONE simulator and using real human mobility traces.

  18. Friendly-Sharing: Improving the Performance of City Sensoring through Contact-Based Messaging Applications

    Science.gov (United States)

    Herrera-Tapia, Jorge; Hernández-Orallo, Enrique; Tomás, Andrés; Manzoni, Pietro; Tavares Calafate, Carlos; Cano, Juan-Carlos

    2016-01-01

    Regular citizens equipped with smart devices are being increasingly used as “sensors” by Smart Cities applications. Using contacts among users, data in the form of messages is obtained and shared. Contact-based messaging applications are based on establishing a short-range communication directly between mobile devices, and on storing the messages in these devices for subsequent delivery to cloud-based services. An effective way to increase the number of messages that can be shared is to increase the contact duration. We thus introduce the Friendly-Sharing diffusion approach, where, during a contact, the users are aware of the time needed to interchange the messages stored in their buffers, and they can thus decide to wait more time in order to increase the message sharing probability. The performance of this approach is anyway closely related to the size of the buffer in the device. We therefore compare various policies either for the message selection at forwarding times and for message dropping when the buffer is full. We evaluate our proposal with a modified version of the Opportunistic Networking Environment (ONE) simulator and using real human mobility traces. PMID:27649209

  19. Are Friends Overrated?: A Study for the Social Aggregator Digg.com

    NARCIS (Netherlands)

    Doerr, C.; Tang, S.; Blenn, N.; Van Mieghem, P.

    2011-01-01

    The key feature of online social networks is the ability of users to become active, make friends and interact with those around them. Such interaction is typically perceived as critical to these platforms; therefore, a significant share of research has investigated the characteristics of social link

  20. Synchronous identification of friendly targets

    Science.gov (United States)

    Telle, John M.; Roger, Stutz A.

    1998-01-01

    A synchronous communication targeting system for use in battle. The present invention includes a transceiver having a stabilizing oscillator, a synchronous amplifier and an omnidirectional receiver, all in electrical communication with each other. A remotely located beacon is attached to a blackbody radiation source and has an amplitude modulator in electrical communication with a optical source. The beacon's amplitude modulator is set so that the optical source transmits radiation frequency at approximately the same or lower amplitude than that of the blackbody radiation source to which the beacon is attached. The receiver from the transceiver is adapted to receive frequencies approximately at or below blackbody radiation signals and sends such signals to the synchronous amplifier. The synchronous amplifier then rectifies and amplifies those signals which correspond to the predetermined frequency to therefore identify whether the blackbody radiation source is friendly or not.

  1. Language as friend and foe

    DEFF Research Database (Denmark)

    Glaveanu, Vlad Petre

    If the limits of our language are the limits of our world, in the famous Wittgensteinian formulation, we can confidently add that they are also the limits of our theories and methodologies. The terms we use to conceptualise psychological and social phenomena often reify and dichotomise realities...... that are otherwise both integrated and dynamic. How can we use language in research that captures both content and process, both meaning and action, both the conscious and the subconscious, both the individual and the social (and the list can continue...)? Illustrations of the _dangers_ of terminology...... will be offered from the field of creativity studies. A collective creative exercise will be set in place in order to overcome these barriers in our thinking and, consequently, in our acting in and on the world. Linguistic creativity, will be argued, should be the _best friend_ of researchers engaged...

  2. Towards tooth friendly soft drinks.

    Science.gov (United States)

    Kolahi, Jafar; Fazilati, Mohamad; Kadivar, Mahdi

    2009-10-01

    Most soft drinks contain high concentration of simple carbohydrates and have a pH of 3 or even lower. Therefore, they are harmful for tooth structure. A tooth friendly soft drink (T.F.S.D) should have the following characteristics and elements; fluoride (approximately 1 ppm), casein phosphopeptide-amorphous calcium phosphate (2%), xylitol (4-6g/serving), tea polyphenols (2-4 mg/ml), cranberry extract (250 mg/ml of the flavonoids quercetin and myricetin), sugar free, pH close to 5.5 and super oxygenation (240,000 ppm) vs. carbonation. T.F.S.D can be packaged in a container which gaseous oxygen is dissolved in a liquid in the form of bubbles. However, looking at opportunities for so-called sophisticated soft drinks, T.F.S.D will be an example for a functional and health oriented soft drink.

  3. You Don't De-Friend the Dead: An Analysis of Grief Communication by College Students through Facebook Profiles

    Science.gov (United States)

    Pennington, Natalie

    2013-01-01

    This research examined how various members of a social network interact with the Facebook (FB) profile page of a friend who has died. From 43 in-depth qualitative interviews, FB friends of deceased FB users maintained their FB connection with the deceased. Most participants who visited the profile found it helpful to look at pictures; a few wrote…

  4. Friends don't let friends eat cookies: effects of restrictive eating norms on consumption among friends.

    Science.gov (United States)

    Howland, Maryhope; Hunger, Jeffrey M; Mann, Traci

    2012-10-01

    Social norms are thought to be a strong influence over eating, but this hypothesis has only been experimentally tested with groups of strangers, and correlational studies using actual friends lack important controls. We manipulate an eating norm in the laboratory and explore its influence within established friendships. In two studies we randomly assigned groups of three friends to a restrictive norm condition, in which two of the friends were secretly instructed to restrict their intake of appetizing foods, or a control condition, in which the friends were not instructed to restrict their eating. The third friend's consumption was measured while eating with the other two friends and while eating alone. In both studies, participants consumed less food when eating with friends who had been given restricting instructions compared to those who had not been given those instructions. In Study 2, participants who ate with restricting friends also continued to restrict their eating when alone. Experimentally manipulating social norms within established friendships is possible, and these norms can influence consumption in those social groups and carry over into non-social eating situations. These findings may suggest mechanisms through which eating behaviors may spread through social networks, as well as an environmental factor that may be amenable to change.

  5. Metadata: A user`s view

    Energy Technology Data Exchange (ETDEWEB)

    Bretherton, F.P. [Univ. of Wisconsin, Madison, WI (United States); Singley, P.T. [Oak Ridge National Lab., TN (United States)

    1994-12-31

    An analysis is presented of the uses of metadata from four aspects of database operations: (1) search, query, retrieval, (2) ingest, quality control, processing, (3) application to application transfer; (4) storage, archive. Typical degrees of database functionality ranging from simple file retrieval to interdisciplinary global query with metadatabase-user dialog and involving many distributed autonomous databases, are ranked in approximate order of increasing sophistication of the required knowledge representation. An architecture is outlined for implementing such functionality in many different disciplinary domains utilizing a variety of off the shelf database management subsystems and processor software, each specialized to a different abstract data model.

  6. Developing a Child Friendly Text-to-Speech System

    Directory of Open Access Journals (Sweden)

    Agnes Jacob

    2008-01-01

    Full Text Available This paper discusses the implementation details of a child friendly, good quality, English text-to-speech (TTS system that is phoneme-based, concatenative, easy to set up and use with little memory. Direct waveform concatenation and linear prediction coding (LPC are used. Most existing TTS systems are unit-selection based, which use standard speech databases available in neutral adult voices. Here reduced memory is achieved by the concatenation of phonemes and by replacing phonetic wave files with their LPC coefficients. Linguistic analysis was used to reduce the algorithmic complexity instead of signal processing techniques. Sufficient degree of customization and generalization catering to the needs of the child user had been included through the provision for vocabulary and voice selection to suit the requisites of the child. Prosody had also been incorporated. This inexpensive TTS system was implemented in MATLAB, with the synthesis presented by means of a graphical user interface (GUI, thus making it child friendly. This can be used not only as an interesting language learning aid for the normal child but it also serves as a speech aid to the vocally disabled child. The quality of the synthesized speech was evaluated using the mean opinion score (MOS.

  7. Phil Friend julgustab riske võtma / Phil Friend ; interv. Harda Roosna

    Index Scriptorium Estoniae

    Friend, Phil

    2003-01-01

    Suurbritannia koolitus- ja konsultatsioonifirma Churchill & Friend juhataja Phil Friend vastab küsimustele oma firma missiooni kohta Hiiumaal, puuetega inimeste elu erinevuste kohta Hiiumaal ja Suurbritannias. Vt. samas: Phil Friend julgustas tööandjaid puuetega inimesi tööle võtma

  8. Phil Friend julgustab riske võtma / Phil Friend ; interv. Harda Roosna

    Index Scriptorium Estoniae

    Friend, Phil

    2003-01-01

    Suurbritannia koolitus- ja konsultatsioonifirma Churchill & Friend juhataja Phil Friend vastab küsimustele oma firma missiooni kohta Hiiumaal, puuetega inimeste elu erinevuste kohta Hiiumaal ja Suurbritannias. Vt. samas: Phil Friend julgustas tööandjaid puuetega inimesi tööle võtma

  9. Best Friend Networks of Children across Settings.

    Science.gov (United States)

    Ray, Glen E.; And Others

    1995-01-01

    Investigated children's classroom sociometry and size of their best-friend networks. For both classroom and playground settings, popular children had the most reciprocal best friends, while rejected children had the fewest, but had more on the playground than in the classroom. Results suggest that constraints and opportunities of different…

  10. User-based and Cognitive Approaches to Knowledge Organization

    DEFF Research Database (Denmark)

    Hjørland, Birger

    2013-01-01

    In the 1970s and 1980s, forms of user-based and cognitive approaches to knowledge organization came to the forefront as part of the overall development in library and information science and in the broader society. The specific nature of userbased approaches is their basis in the empirical studies...... of users or the principle that users need to be involved in the construction of knowledge organization systems. It might seem obvious that user-friendly systems should be designed on user studies or user involvement, but extremely successful systems such as Apple’s iPhone, Dialog’s search system and Google......’s PageRank are not based on the empirical studies of users. In knowledge organization, the Book House System is one example of a system based on user studies. In cognitive science the important WordNet database is claimed to be based on psychological research. This article considers such examples...

  11. Spillover of environment-friendly consumer behaviour

    DEFF Research Database (Denmark)

    Thøgersen, John; Ølander, Carl Folke

    2003-01-01

    of structural equation modelling and other techniques. Cases of transfer of environment-friendly conduct between behavioural categories are found, but only in a few of the possible instances and only of a modest size. The panel analysis also identifies a few negative cross-lagged effects. Such effects may......This paper contributes empirical input to current reasoning about consumers' propensity to behave in an environmentally friendly way in different domains. Spe-cifically, we investigate whether environmentally friendly behaviours spread to more and more areas of the consumption pattern in a virtuous...... indicate that the performance of an environmentally friendly behaviour reduces the propensity to behave environmentally friendly in other areas. However, they may also be the result of the two involved behaviours correlating positively from the out-set. Multigroup SEM analyses indicate that the likelihood...

  12. Transmission Line Jobs and Economic Development Impact (JEDI) Model User Reference Guide

    Energy Technology Data Exchange (ETDEWEB)

    Goldberg, M.; Keyser, D.

    2013-10-01

    The Jobs and Economic Development Impact (JEDI) models, developed through the National Renewable Energy Laboratory (NREL), are freely available, user-friendly tools that estimate the potential economic impacts of constructing and operating power generation projects for a range of conventional and renewable energy technologies. The Transmission Line JEDI model can be used to field questions about the economic impacts of transmission lines in a given state, region, or local community. This Transmission Line JEDI User Reference Guide was developed to provide basic instruction on operating the model and understanding the results. This guide also provides information on the model's underlying methodology, as well as the parameters and references used to develop the cost data contained in the model.

  13. Addressing Earth Science Data Access Challenges through User Experience Research

    Science.gov (United States)

    Hemmings, S. N.; Banks, B.; Kendall, J.; Lee, C. M.; Irwin, D.; Toll, D. L.; Searby, N. D.

    2013-12-01

    The NASA Capacity Building Program (Earth Science Division, Applied Sciences Program) works to enhance end-user capabilities to employ Earth observation and Earth science (EO/ES) data in decision-making. Open data access and user-tailored data delivery strategies are critical elements towards this end. User Experience (UX) and User Interface (UI) research methods can offer important contributions towards addressing data access challenges, particularly at the interface of science application/product development and product transition to end-users. This presentation focuses on developing nation contexts and describes methods, results, and lessons learned from two recent UX/UI efforts conducted in collaboration with NASA: the SERVIRglobal.net redesign project and the U.S. Water Partnership (USWP) Portal development effort. SERVIR, a collaborative venture among NASA, USAID, and global partners, seeks to improve environmental management and climate change response by helping governments and other stakeholders integrate EO and geospatial technologies into decision-making. The USWP, a collaboration among U.S. public and private sectors, harnesses U.S.-based resources and expertise to address water challenges in developing nations. SERVIR's study, conducted from 2010-2012, assessed and tested user needs, preferences, and online experiences to generate a more user-friendly online data portal at SERVIRglobal.net. The portal provides a central access interface to data and products from SERVIR's network of hubs in East Africa, the Hindu Kush Himalayas, and Mesoamerica. The second study, conducted by the USWP Secretariat and funded by the U.S. Department of State, seeks to match U.S.-based water information resources with developing nation stakeholder needs. The USWP study utilizes a multi-pronged approach to identify key design requirements and to understand the existing water data portal landscape. Adopting UX methods allows data distributors to design customized UIs that

  14. Design and implementation of a computational processing system for off-line digital close-range photogrammetry

    Science.gov (United States)

    Fraser, Clive S.; Edmundson, Kenneth L.

    Through the adoption of recent innovations in automation in vision metrology, it can be demonstrated that rigorous, yet user-friendly digital photogrammetric processes of calibration and orientation/triangulation can be incorporated into a computational scheme which is on the one hand capable of meeting the demands of high metric quality, while on the other offering the facilities necessary to support wider application by non-specialist users. The software system Australis, developed for image mensuration and restitution of off-line close-range photogrammetric networks, is featured to illustrate these processes and procedures. By describing the structure and components of Australis, the authors aim to demonstrate that many processes which have on occasion been viewed to be the exclusive province of automated, high-precision vision metrology are indeed suited to more general application across a broad range of fields which involve 3D object recording via close-range imagery.

  15. Justine user`s manual

    Energy Technology Data Exchange (ETDEWEB)

    Lee, S.R.

    1995-10-01

    Justine is the graphical user interface to the Los Alamos Radiation Modeling Interactive Environment (LARAMIE). It provides LARAMIE customers with a powerful, robust, easy-to-use, WYSIWYG interface that facilitates geometry construction and problem specification. It is assumed that the reader is familiar with LARAMIE, and the transport codes available, i.e., MCNPTM and DANTSYSTM. No attempt is made in this manual to describe these codes in detail. Information about LARAMIE, DANTSYS, and MCNP are available elsewhere. It i also assumed that the reader is familiar with the Unix operating system and with Motif widgets and their look and feel. However, a brief description of Motif and how one interacts with it can be found in Appendix A.

  16. Second Language Users and Emerging English Designs

    Science.gov (United States)

    Jordan, Jay

    2009-01-01

    As English spreads as an international language, it evolves through diverse users' writing and speaking. However, traditional views of ESL users focus on their distance from fairly static notions of English-language competence. This research uses a grounded theory approach to describe a range of competencies that emerge in ESL users' interactions…

  17. Stochastic Models Predict User Behavior in Social Media

    CERN Document Server

    Hogg, Tad; Smith, Laura M

    2013-01-01

    User response to contributed content in online social media depends on many factors. These include how the site lays out new content, how frequently the user visits the site, how many friends the user follows, how active these friends are, as well as how interesting or useful the content is to the user. We present a stochastic modeling framework that relates a user's behavior to details of the site's user interface and user activity and describe a procedure for estimating model parameters from available data. We apply the model to study discussions of controversial topics on Twitter, specifically, to predict how followers of an advocate for a topic respond to the advocate's posts. We show that a model of user behavior that explicitly accounts for a user transitioning through a series of states before responding to an advocate's post better predicts response than models that fail to take these states into account. We demonstrate other benefits of stochastic models, such as their ability to identify users who a...

  18. Agriculture, forest, and range

    Science.gov (United States)

    1975-01-01

    The findings and recommendations of the panel for developing a satellite remote-sensing global information system in the next decade are reported. User requirements were identified in five categories: (1) cultivated crops, (2) land resources, (3)water resources, (4)forest management, and (5) range management. The benefits from the applications of satellite data are discussed.

  19. Nordic Analysis of Climate Friendly Buildings

    DEFF Research Database (Denmark)

    Andresen, Inger; Thomsen, Kirsten Engelund; Wahlstrøm, Åsa;

    This report summarizes the findings of the work conducted within the project “Nordic Analysis of Climate Friendly Buildings”, financed by the Nordic Council of Ministers. The main goal of the project was to establish a knowledge and decision base for a Nordic innovation program that will promote...... the development and demonstration of low energy and climate friendly buildings. The innovation program should support a development that brings the Nordic countries to an international forefront with respect to business strongholds and market penetration of low energy and climate friendly buildings....

  20. The Users Office turns 20

    CERN Multimedia

    2009-01-01

    20 years ago, in the summer of 1989, an office was created to assist the thousands of users who come to CERN each year, working over the broad range of projects and collaborations. Chris Onions (right), head of the Users’ Office, with Bryan Pattison (left), the Office’s founder.Before the inception of the Users Office, it was common for users to spend at least an entire day moving from office to office in search of necessary documentation and information in order to make their stay official. "Though the Office has undergone various changes throughout its lifetime, it has persisted in being a welcoming bridge to facilitate the installation of visitors coming from all over the world", says Chris Onions, head of the Users Office. This September, the Office will celebrate its 20-year anniversary with a drink offered to representatives of the User community, the CERN management and staff members from the services with whom the Office is involved. &...

  1. SILMUSCEN and CLIGEN User`s Guide

    Energy Technology Data Exchange (ETDEWEB)

    Carter, T.; Tuomenvirta, H. [Finnish Meteorological Inst., Helsinki (Finland); Posch, M. [Water and Environment Research Inst., Helsinki (Finland)

    1995-12-31

    This User`s Guide has been prepared to provide recommendations for the selection and application of climatic scenarios in the Finnish Research Programme on Climate Change (SILMU). These scenarios are required for conducting impact studies in SILMU. They should reflect the current range of estimates of future climate in the Finnish region. In addition, they should be consistent with other projections of importance in impact studies, such as future atmospheric composition and sea level. Section 2 provides some background information about the types of scenarios required in SILMU and Section 3 offers a general description of the scenarios. In Section 4 there is some advice on applying sensitivity studies to complement the use of scenarios. Section 5 explains the installation of the SILMUSCEN program and Section 6 guides the user through some examples to illustrate how SILMUSCEN can be used. Section 7 offers some recommendations on which scenarios to adopt for different impact assessments. In order to ensure some compatibility between impact studies in SILMU, it is very important that the recommendations in this section are followed as far as possible. Section 8 addresses important omissions from the computer program and suggests procedures to adopt in their absence. Section 9 explores alternative methods of specifying the baseline climate, and shows how scenario adjustments to the baseline can be made. in Section 10, the stochastic weather generator, CLIGEN, is described and its use illustrated by means of examples. Finally, possible refinements of the programs are outlined in Section 11, along with contact names and addresses for obtaining further information. (36 refs.)

  2. Romantic Partners, Friends, Friends with Benefits, and Casual Acquaintances As Sexual Partners

    Science.gov (United States)

    Furman, Wyndol; Shaffer, Laura

    2011-01-01

    The purpose of the present study was to provide a detailed examination of sexual behavior with different types of partners. A sample of 163 young adults reported on their light nongenital, heavy nongenital, and genital sexual activity with romantic partners, friends, and casual acquaintances. They described their sexual activity with “friends with benefits” as well as with friends in general. Young adults were most likely to engage in sexual behavior with romantic partners, but sexual behavior also often occurred with some type of nonromantic partner. More young adults engaged in some form of sexual behavior with casual acquaintances than with friends with benefits. The frequencies of sexual behavior, however, were greater with friends with benefits than with friends or casual acquaintances. Interview and questionnaire data revealed that friends with benefits were typically friends, but not necessarily. Nonsexual activities were also less common with friends with benefits than other friends. Taken together, the findings illustrate the value of differentiating among different types of nonromantic partners and different levels of sexual behavior. PMID:21128155

  3. Dynamic Bridge Response for a Bridge-friendly Truck

    Directory of Open Access Journals (Sweden)

    V. Šmilauer

    2004-01-01

    Full Text Available A truck with controlled semi-active suspensions traversing a bridge is examined for benefits to the bridge structure. The original concept of a road-friendly truck was extended to a bridge-friendly vehicle, using the same optimization tools. A half-car model with two independently driven axles is coupled with simply supported bridges (beam, slab model with the span range from 5 m to 50 m. Surface profile of the bridge deck is either stochastic or in the shape of a bump or a pot in the mid-span. Numerical integration in the MATLAB/SIMULINK environment solves coupled dynamic equations of motion with optimized truck suspensions. The rear axle generates the prevailing load and to a great extent determines the bridge response. A significant decrease in contact road-tire forces is observed and the mid-span bridge deflections are on average smaller, when compared to commercial passive suspensions. 

  4. A process evaluation of the scale up of a youth-friendly health services initiative in northern Tanzania

    Directory of Open Access Journals (Sweden)

    Renju Jenny

    2010-08-01

    Full Text Available Abstract Background While there are a number of examples of successful small-scale, youth-friendly services interventions aimed at improving reproductive health service provision for young people, these projects are often short term and have low coverage. In order to have a significant, long-term impact, these initiatives must be implemented over a sustained period and on a large scale. We conducted a process evaluation of the 10-fold scale up of an evaluated youth-friendly services intervention in Mwanza Region, Tanzania, in order to identify key facilitating and inhibitory factors from both user and provider perspectives. Methods The intervention was scaled up in two training rounds lasting six and 10 months. This process was evaluated through the triangulation of multiple methods: (i a simulated patient study; (ii focus group discussions and semi-structured interviews with health workers and trainers; (iii training observations; and (iv pre- and post-training questionnaires. These methods were used to compare pre- and post-intervention groups and assess differences between the two training rounds. Results Between 2004 and 2007, local government officials trained 429 health workers. The training was well implemented and over time, trainers' confidence and ability to lead sessions improved. The district-led training significantly improved knowledge relating to HIV/AIDS and puberty (RR ranged from 1.06 to 2.0, attitudes towards condoms, confidentiality and young people's right to treatment (RR range: 1.23-1.36. Intervention health units scored higher in the family planning and condom request simulated patient scenarios, but lower in the sexually transmitted infection scenario than the control health units. The scale up faced challenges in the selection and retention of trained health workers and was limited by various contextual factors and structural constraints. Conclusions Youth-friendly services interventions can remain well delivered, even

  5. User interface design for iOS camera application : project: designing gif video camera application

    OpenAIRE

    Kim, Erika

    2016-01-01

    The objective of this thesis was to examine the fundamentals and basic principles of great user experience and user interface design. The focus was on laying out theoretical foundations and applying them into a practical end result – a camera application with a simple and user friendly graphical interface. In order to set up the foundations of the thesis, a comprehensive research into the many different factors that, as a whole, make up a good user experience was conducted. Throughout section...

  6. My Friend Is Talking about Suicide

    Science.gov (United States)

    ... Healthy Breakfasts Shyness My Friend Is Talking About Suicide. What Should I Do? KidsHealth > For Teens > My ... sobre suicidio. ¿Qué debo hacer? Warning Signs of Suicide Everyone feels sad, depressed, or angry sometimes — especially ...

  7. Spillover of environment-friendly consumer behaviour

    DEFF Research Database (Denmark)

    Thøgersen, John; Ølander, Carl Folke

    2003-01-01

    This paper contributes empirical input to current reasoning about consumers' propensity to behave in an environmentally friendly way in different domains. Spe-cifically, we investigate whether environmentally friendly behaviours spread to more and more areas of the consumption pattern in a virtuous...... circle and whether it is a necessary prerequisite for a virtuous circle to emerge and to continue to work that the individual possesses certain general values or ethical norms. The data material is a three-wave panel study with a large random sample of Danish consumers. The data were analysed by means...... indicate that the performance of an environmentally friendly behaviour reduces the propensity to behave environmentally friendly in other areas. However, they may also be the result of the two involved behaviours correlating positively from the out-set. Multigroup SEM analyses indicate that the likelihood...

  8. My Friend Is Talking about Suicide

    Science.gov (United States)

    ... for You Shyness My Friend Is Talking About Suicide. What Should I Do? KidsHealth > For Teens > My ... sobre suicidio. ¿Qué debo hacer? Warning Signs of Suicide Everyone feels sad, depressed, or angry sometimes — especially ...

  9. Korean Friend Receiving Title of Friendship Ambassador

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    The CPAFFC held a ceremony on October 8, 2003 to confer the title of Friendship Ambassador upon Korean friend Lee Ik Soon in recognition of his outstanding contributions to the cause of Sino-Korean friendship.

  10. "The Friendly Clergy": Characteristics and Referral.

    Science.gov (United States)

    Faiver, Christopher M.; O'Brien, Eugene M.; McNally, Christopher J.

    1998-01-01

    Among the recommendations possible in assessment of clients' religious beliefs is that of referral to the "friendly clergy." Delineates guidelines for referral as well as ideal characteristics of that spiritual profession. (Author)

  11. Offering Spiritual Support for Family or Friends

    Science.gov (United States)

    Offering Spiritual Support for Family or Friends People who are very ill often ask spiritual questions, in seeking comfort, meaning and hope. While clergy, chaplains and other spiritual leaders may play an important role in spiritual ...

  12. Diabetes-Friendly Meal Everyone Can Enjoy

    Science.gov (United States)

    ... of this page please turn Javascript on. Feature: Diabetes A Diabetes-Friendly Meal Everyone Can Enjoy Past Issues / Fall 2009 Table of Contents From the National Diabetes Education Program (NDEP) Knowing what to serve and ...

  13. User centered integration of Internet of Things devices

    Science.gov (United States)

    Manione, Roberto

    2017-06-01

    This paper discusses an IoT framework which allows rapid and easy setup and customization of end-to-end solutions for field data collection and presentation; it is effective in the development of both informative and transactional applications for a wide range of application fields, such as home, industry and environment. On the "far-end" of the chain are the IoT devices gathering the signals; they are developed used a full Model Based approach, where programming is not required: the TaskScript technology is used to this purpose, which supports a choice of physical boards and boxes equipped with a range of Input and Output interfaces, and with a Tcp/Ip interface. The development of the needed specific IoT devices takes advantage of the available "standard" hardware; the software development of the algorithms for sampling, conditioning and uploading signals to the Cloud is supported by a graphical-only IDE. On the "near-end" of the chain is the presentation Interface, through which users can browse through the information provided by their IoT devices; it is implemented in a Conversational way, using the Bot paradigm: Bots are conversational automatons, to whom users can "chat". They are accessed via mainstream Messenger programs, such as Telegram(C), Skype(C) or others, available on smartphones, tablets or desktops; unlike apps, bots do not need installation on the user device. A message Broker has been implemented, to mediate among the far-end and the near-end of the chain, providing the needed services; its behavior is driven by a set of rules provided on a per-device basis, at configuration level; the Broker is able to store messages received from the devices, process and forward them to the specified recipient(s) according to the provided rules; finally, finally is it is able to send transactional commands, from users back to the requested device, to implement not only field observation but also field control. IoT solutions implemented with the proposed

  14. Friends of the National Library of Medicine - Letter from Friends of the NLM Chairman Paul G. Rogers

    Science.gov (United States)

    ... Bar Home Current Issue Past Issues Letter from Friends of the NLM Chairman Paul G. Rogers Past ... and recommend medlineplus.gov to your family and friends. On behalf of the Friends of the National ...

  15. Mobile-friendly web design and development

    OpenAIRE

    Heyiredin, Daniel

    2013-01-01

    This study deals with the current technology how to optimized mobile friendly web design and development. The conception of this thesis idea Mobile-friendly web design and development was conceived by a colleague during a visit to Nokia Company. The purpose of this paper is to show how to build compelling easy to use website which is optimized to today’s mobile devices. Web application developers and companies who wants to optimize their products for mobile devices could also benefit ...

  16. Independence-friendly cylindric set algebras

    CERN Document Server

    Mann, Allen L

    2007-01-01

    Independence-friendly logic is a conservative extension of first-order logic that has the same expressive power as existential second-order logic. In her Ph.D. thesis, Dechesne introduces a variant of independence-friendly logic called IFG logic. We attempt to algebraize IFG logic in the same way that Boolean algebra is the algebra of propositional logic and cylindric algebra is the algebra of first-order logic. We define independence-friendly cylindric set algebras and prove two main results. First, every independence-friendly cylindric set algebra over a structure has an underlying Kleene algebra. Moreover, the class of such underlying Kleene algebras generates the variety of all Kleene algebras. Hence the equational theory of the class of Kleene algebras that underly an independence-friendly cylindric set algebra is finitely axiomatizable. Second, every one-dimensional independence-friendly cylindric set algebra over a structure has an underlying monadic Kleene algebra. However, the class of such underlyin...

  17. FRIEND Engine Framework: A real time neurofeedback client-server system for neuroimaging studies

    Directory of Open Access Journals (Sweden)

    Rodrigo eBasilio

    2015-01-01

    Full Text Available In this methods article, we present a new implementation of a recently reported FSL-integrated neurofeedback tool, the standalone version of Functional Real-time Interactive Endogenous Modulation and Decoding (FRIEND. We will refer to this new implementation as the FRIEND Engine Framework. The framework comprises a client-server cross-platform solution for real time fMRI and fMRI/EEG neurofeedback studies, enabling flexible customization or integration of graphical interfaces, devices and data processing. This implementation allows a fast setup of novel plug-ins and frontends, which can be shared with the user community at large. The FRIEND Engine Framework is freely distributed for non-commercial, research purposes.

  18. User-Based Information Search across Multiple Social Media

    OpenAIRE

    Gåre, Marte Lise

    2015-01-01

    Most of todays Internet users are registered to one or more social media applications. As so many are registered to multiple application, it has become difficult to locate friends, former colleagues, peers and acquaintances. Reasons for this include private profiles, name collisions, multiple usernames, lack of profile attributes and profile picture. The system designed and implemented in this thesis enable automatic user-based information search across multiple social media without relyi...

  19. Friend or foe: Personal use and friends' use of protective behavioral strategies and spring break drinking.

    Science.gov (United States)

    Lewis, Melissa A; Sheng, Elisa; Geisner, Irene M; Rhew, Isaac C; Patrick, Megan E; Lee, Christine M

    2015-11-01

    The present study examined associations between use of protective behavioral strategies (PBS) by college students and their friends and drinking-related outcomes during Spring Break (SB). Moreover, this study examined the influence of friends' own PBS use on participants' PBS use during SB. Participants included college students (N = 694) and their nominated friends (N = 131) who were part of a larger study of SB drinking. Data were collected via web-based surveys that participants and friends took after SB, which assessed SB PBS, drinking, and related negative consequences. Results indicated that higher levels of Serious Harm Reduction (SHR) strategies and Limiting/Stopping (LS) strategies were associated with increased consumption, higher likelihood of experiencing any consequences, and an increased number of consequences. A different pattern emerged for Manner of Drinking (MD) strategy use; participants utilizing higher levels of MD strategies drank less and had fewer consequences. LS and MD strategies used by the participant's friends appeared to have less of an impact on the participant's drinking outcomes. However, greater friends' use of SHR strategies was associated with increased alcohol use by the participant, but not with consequences. Greater friends' use of SHR strategies was associated with greater SHR strategy use by the participant. Friends' LS and MD strategies were not associated with participant drinking, consequences, or PBS. These findings highlight the potential utility of interventions that focus on drinking behaviors on specific high-risk occasions for those at risk as well as for their friends.

  20. An Eco-friendly, Scaled-down Gram Stain Protocol

    Directory of Open Access Journals (Sweden)

    Ruth A. Gyure

    2010-04-01

    Full Text Available Currently, flushing large volumes of Gram stain reagents into sanitary sewage systems is no longer acceptable. These chemical wastes are highly regulated and must be collected, labeled, and disposed of in a responsible manner, usually by paying a commercial service to remove them to an authorized off-site facility. Such services are costly and, as expected, costs are proportional to volume of collected waste. This “old” method of Gram staining, even if effluent is collected, generates a high volume of liquid waste which is unnecessarily diluted with additional large volumes of water from the rinsing steps. The purpose of using this scaled-down and eco-friendly protocol is to dramatically reduce the amount of liquid waste produced without sacrificing quality of results. This protocol is flexible, practical, and easy to implement. It does not require students to work at a bench sink, reduces user cost, and lowers environmental impact overall.

  1. Collaborative User Network Embedding for Social Recommender Systems

    KAUST Repository

    Zhang, Chuxu

    2017-06-09

    To address the issue of data sparsity and cold-start in recommender system, social information (e.g., user-user trust links) has been introduced to complement rating data for improving the performances of traditional model-based recommendation techniques such as matrix factorization (MF) and Bayesian personalized ranking (BPR). Although effective, the utilization of the explicit user-user relationships extracted directly from such social information has three main limitations. First, it is difficult to obtain explicit and reliable social links. Only a small portion of users indicate explicitly their trusted friends in recommender systems. Second, the “cold-start” users are “cold” not only on rating but also on socializing. There is no significant amount of explicit social information that can be useful for “cold-start” users. Third, an active user can be socially connected with others who have different taste/preference. Direct usage of explicit social links may mislead recommendation. To address these issues, we propose to extract implicit and reliable social information from user feedbacks and identify top-k semantic friends for each user. We incorporate the top-k semantic friends information into MF and BPR frameworks to solve the problems of ratings prediction and items ranking, respectively. The experimental results on three real-world datasets show that our proposed approaches achieve better results than the state-of-the-art MF with explicit social links (with 3.0% improvement on RMSE), and social BPR (with 9.1% improvement on AUC).

  2. Achieving People Friendly Accessibility. Key Concepts and a Case Study Overview

    Directory of Open Access Journals (Sweden)

    Michela Tiboni

    2014-05-01

    Full Text Available The present paper stems from the evidence that one of the reasons of the “crisis” of today's cities probably depend on mobility issues.   But what should be done to confront all the negative impacts of passenger transportation, without curbing mobility? Can Urban Engineering be applied to promote a friendlier mobility, that should be not only environment and climate friendly, but user friendly as well? And how? A "people friendly" accessibility approach is presented and conceived as a solution to better integrate land uses with the transport system, satisfying people's expectations (especially those of vulnerable users to easily reach the opportunities they wish to engage with.  The case study of Amsterdam, as walkable and cycle friendly city, is briefly presented and reveal good practices in the field of urban and mobility planning.  Finally, an isochronical accessibility analysis of Amsterdam is applied: it represent catchment areas of railways stations and of supermarkets, and it highlights how much the structure of the city supports bicycle use.

  3. The more friends, the less political talk? Predictors of Facebook discussions among college students.

    Science.gov (United States)

    Jang, S Mo; Lee, Hoon; Park, Yong Jin

    2014-05-01

    Although previous research has indicated that Facebook users, especially young adults, can cultivate their civic values by talking about public matters with their Facebook friends, little research has examined the predictors of political discussion on Facebook. Using survey data from 442 college students in the United States, this study finds that individual characteristics and network size influence college students' expressive behavior on Facebook related to two controversial topics: gay rights issues and politics. In line with previous studies about offline political discussion, the results show that conflict avoidance and ambivalence about target issues are negatively associated with Facebook discussions. Perhaps the most interesting finding is that users who have a large number of Facebook friends are less likely to talk about politics and gay rights issues on Facebook despite having access to increasing human and information resources. Theoretical implications of these findings and future directions are addressed.

  4. Student Attitudes toward Intimacy with Persons Who Are Wheelchair Users

    Science.gov (United States)

    Marini, Irmo; Chan, Roy; Feist, Amber; Flores-Torres, Lelia

    2011-01-01

    The present study explored whether students would be attracted to having an intimate relationship with a wheelchair user if participants were able to first see a head shot photo and later read a short biography of the person. Four hundred and eight undergraduate students were surveyed regarding their interest in potentially being friends, dating…

  5. User`s guide and physics manual for the SCATPlus circuit code

    Energy Technology Data Exchange (ETDEWEB)

    Yapuncich, M.L.; Deninger, W.J.; Gribble, R.F.

    1994-05-09

    ScatPlus is a user friendly circuit code and an expandable library of circuit models for electrical components and devices; it can be used to predict the transient behavior in electric circuits. The heart of ScatPlus is the transient circuit solver SCAT written in 1986 by R.F. Gribble. This manual includes system requirements, physics manual, ScatPlus component library, tutorial, ScatPlus screen, menus and toolbar, ScatPlus tool bar, procedures.

  6. Network user`s guide

    Energy Technology Data Exchange (ETDEWEB)

    McGrady, P.W.

    1994-12-01

    NETWORK is a FORTRAN code used to model process flow systems in the gaseous diffusion plants at Portsmouth, Ohio and Paducah, Kentucky, operated by the United States Enrichment Corporation. It can handle a wide range of components and several different types of controllers. NETWORK can be run in either a steady-state mode or a transient mode. In the transient mode many different types of perturbations may be modeled. It is currently being used to model taking a cell off-stream in a gaseous diffusion plant. A brief description of the code is given, and process equipment models and input data are discussed.

  7. User Interface Program for secure electronic tags

    Energy Technology Data Exchange (ETDEWEB)

    Cai, Y.; Koehl, E.R.; Carlson, R.D.; Raptis, A.C.

    1995-05-01

    This report summarizes and documents the efforts of Argonne National Laboratory (ANL) in developing a secure tag communication user interface program comprising a tag monitor and a communication tool. This program can perform the same functions as the software that was developed at the Lawrence Livermore National Laboratory (LLNL), but it is enhanced with a user-friendly screen. It represents the first step in updating the TRANSCOM Tracking System (TRANSCOM) by incorporating a tag communication screen menu into the main menu of the TRANSCOM user program. A working version of TRANSCOM, enhanced with ANL secure-tag graphics, will strongly support the Department of Energy Warhead Dismantlement/Special Nuclear Materials Control initiatives. It will allow commercial satellite tracking of the movements and operational activities of treaty-limited items and transportation vehicles throughout Europe and the former USSR, as well as the continental US.

  8. Petroleum Refinery Jobs and Economic Development Impact (JEDI) Model User Reference Guide

    Energy Technology Data Exchange (ETDEWEB)

    Goldberg, M.

    2013-12-31

    The Jobs and Economic Development Impact (JEDI) models, developed through the National Renewable Energy Laboratory (NREL), are user-friendly tools utilized to estimate the economic impacts at the local level of constructing and operating fuel and power generation projects for a range of conventional and renewable energy technologies. The JEDI Petroleum Refinery Model User Reference Guide was developed to assist users in employing and understanding the model. This guide provides information on the model's underlying methodology, as well as the parameters and references used to develop the cost data utilized in the model. This guide also provides basic instruction on model add-in features, operation of the model, and a discussion of how the results should be interpreted. Based on project-specific inputs from the user, the model estimates job creation, earning and output (total economic activity) for a given petroleum refinery. This includes the direct, indirect and induced economic impacts to the local economy associated with the refinery's construction and operation phases. Project cost and job data used in the model are derived from the most current cost estimations available. Local direct and indirect economic impacts are estimated using economic multipliers derived from IMPLAN software. By determining the regional economic impacts and job creation for a proposed refinery, the JEDI Petroleum Refinery model can be used to field questions about the added value refineries may bring to the local community.

  9. How to Make Financial Aid "Freshman-Friendly"

    Science.gov (United States)

    Pugh, Susan L.; Johnson, David B.

    2011-01-01

    Ultimately, making financial aid "freshman friendly" also makes financial aid "sophomore friendly," "junior friendly," and "senior friendly." Indiana University has in place an Office of Enrollment Management (OEM) model that includes focused financial aid packaging strategies complemented by unique contact services and communication interventions…

  10. Socialization of emotion regulation strategies through friends.

    Science.gov (United States)

    Reindl, Marion; Gniewosz, Burkhard; Reinders, Heinz

    2016-06-01

    This study examines the effects of best friends' emotion regulation strategies (regarding the emotions anger, fear, and sadness) on the development of adolescents' emotion regulation strategies and subsequent depressive symptoms. Based on a two-wave longitudinal sample of 238 German adolescents, true change analyses showed positive effects of best friends' adaptive strategies (T1) on the change of adolescents' adaptive strategies (T2 - T1) for anger and fear. Best friends' adaptive strategies (T1) indirectly influence the development of maladaptive strategies (T2 - T1) through the change of adaptive strategies (T2 - T1) and, in turn, the development of depressive symptoms (T2 - T1; two-step mediation). Best friends' adaptive strategies for sadness did not have an effect on adolescents' adaptive strategies. In contrast to adaptive strategies, none of the friends' maladaptive strategies affected adolescents' maladaptive strategies. The results are discussed in terms of peer influences on the development of emotion regulation strategies and psychosocial adjustment.

  11. [Fostering LGBT-friendly healthcare services].

    Science.gov (United States)

    Wei, Han-Ting; Chen, Mu-Hong; Ku, Wen-Wei

    2015-02-01

    LGBT (lesbian, gay, bisexual, transgender) patients suffer from stigma and discrimination when seeking healthcare. A large LGBT healthcare survey revealed that 56% of gay patients and 70% of transgender patients suffered some type of discrimination while seeking healthcare in 2014. The fostering of LGBT-friendly healthcare services is not just an advanced step of gender mainstreaming but also a fulfillment of health equality and equity. Additionally, LGBT-friendly healthcare services are expected to provide new opportunities for healthcare workers. Therefore, proactive government policies, education, research, and clinical practice should all encourage the development of these healthcare services. We look forward to a well-developed LGBT-friendly healthcare system in Taiwan.

  12. [Mother-friendly childbirth practices and breastfeeding].

    Science.gov (United States)

    Lin, Ya-Wen; Tzeng, Ya-Ling; Yang, Ya-Ling

    2013-02-01

    Childbirth, connecting the stages of pregnancy and postpartum, deeply affects maternal motivation with regard to initiating and continuing postnatal breastfeeding and ultimate breastfeeding success. Although promoting breastfeeding is a strategy critical to achieving wellbeing in both mothers and infants, there remains a lack of professional attention and related research into the effect of childbirth on breastfeeding. Promoting successful breastfeeding is a central component of childbirth-friendly nursing care. Therefore, this paper introduces the origin and concepts of mother-and-infant-friendly childbirth, then analyzes the influences on breastfeeding of medicalized birth practices and suggests how to implement childbirth-friendly interventions. This paper was written to help nurses better understand how the childbirth process affects breastfeeding and provide a reference for creating conditions during childbirth that encourage successful breastfeeding practices.

  13. User Evaluation of Neonatology Ward Design.

    Science.gov (United States)

    Trujillo, Juan Luis Higuera; Aviñó, Antoni Montañana I; Millán, Carmen Llinares

    2017-01-01

    The object of this article is to identify the set of affective and emotional factors behind users' assessments of a space in a neonatology unit and to propose design guidelines based on these. The importance of the neonatology service and the variety of users place great demands on the space at all levels. Despite the repercussions, the emotional aspects of the environment have received less attention. To avoid incurring limitations in the user mental scheme, this study uses two complementary methodologies: focus group and semantic differential. The (qualitative) focus group methodology provides exploratory information and concepts. The (quantitative) semantic differential methodology then uses these concepts to extract the conceptual structures that users employ in their assessment of the space. Of the total 175 subjects, 31 took part in focus groups and 144 in semantic differential. Five independent concepts were identified: privacy, functionality and professional nature, spaciousness, lighting, and cleanliness. In relation to the importance of the overall positive assessment of the space, the perception of privacy and sensations of dominance and pleasure are fundamental. Six relevant design aspects were also identified: provide spacious surroundings, facilitate sufficient separation between the different posts or cots, use different colors from those usually found in health-care centers, as some aversion was found to white and especially green, design areas with childhood themes, use warm artificial light, and choose user-friendly equipment. Results provide design recommendations of interest and show the possibilities offered by combining both systems to analyze user response.

  14. The Concept of Environmentally Friendly Individual Mobility in the Future

    Directory of Open Access Journals (Sweden)

    Jasna Golubić

    2012-10-01

    Full Text Available The European cities are faced today by the phenomenon ofexpanding everyday activities, affecting directly the traffic development.Physical expansion, the growing number of cars androad networks explain the increase in car utilisation in all typesof travelling in the range of 75 to 90%.Due to the adverse effects on the environment caused bysuch growing motorisation, the efforts are made in order to establishenvironmentally friendlier traffic. The paper considersthe concept of environmentally friendly individual trafficthrough MCC (Micro Compact Car and MCC- mobility .systemwhich will provide its linking with other traffic participants,which may have a long-term positive influence on the quality ofurban life.

  15. Environmentally friendly pavements: Results from noise measurements 2005-2008

    OpenAIRE

    Berge, Truls Svenn; Haukland, Frode; Ustad, Asbjørn

    2009-01-01

    CPX-measurements (tyre A) have been performed on a wide range of ordinary dense Norwegian road pavements and special test pavements, as part of the R&D project “Environmental friendly pavements” initiated by the Norwegian Public Roads Administration. The following conclusions can be made from the investigation:- New dense asphalt concrete pavements can give a tyre/road noise level (CPX) of 4-8 dB(A) lower noise level, compared to a chosen reference level for a pavement of type AC 0/11 and SMA...

  16. Oxides gets environmentally-friendly

    DEFF Research Database (Denmark)

    Pryds, Nini

    A large amount of thermal energy is available from the waste heat associated with many industrial and social activities of mankind. However, it is difficult to reclaim this heat due to the dispersed nature and relative smallness of its sources. Thermoelectric conversion offers a very promising...... be stable at high temperatures and be composed of nontoxic and low-cost elements, and must be able to be processed and shaped cheaply. Oxides are among the strongest candidate materials for this purpose. This talk provides an overview of the development on such materials at DTU Energy Conversion. In order...... in realizing cooling devices with high efficiency and low global warming potentials, which are highly desirable for a broad range of applications. The technology relies on the magnetocaloric effect in a solid refrigerant rather than the temperature change that occurs when a gas is compressed. This talk...

  17. Oxides gets environmentally-friendly

    DEFF Research Database (Denmark)

    Pryds, Nini

    method to overcome these difficulties by converting heat directly into electricity at the source. However, the requirements for the materials are not easily satisfied even by current state-of-the-art thermoelectric materials. Not only must they possess high thermoelectric performance, they must also...... necessary to demonstrate a working oxide module and develop stable interconnects with low contact resistance as well as mechanical and the chemical stability. In this presentation I will also show our latest results on the performance of oxide module made of ZnO doped Al (n-type) and CaCoO 349 (p-type) [1...... in realizing cooling devices with high efficiency and low global warming potentials, which are highly desirable for a broad range of applications. The technology relies on the magnetocaloric effect in a solid refrigerant rather than the temperature change that occurs when a gas is compressed. This talk...

  18. Usability Testing, User-Centered Design, and LibGuides Subject Guides: A Case Study

    Science.gov (United States)

    Sonsteby, Alec; DeJonghe, Jennifer

    2013-01-01

    Usability testing has become a routine way for many libraries to ensure that their Web presence is user-friendly and accessible. At the same time, popular subject guide creation systems, such as LibGuides, decentralize Web content creation and put authorship into the hands of librarians who may not be trained in user-centered design principles. At…

  19. Family health program user: knowledge and satisfaction about user embracement

    Directory of Open Access Journals (Sweden)

    Saulo Lacerda Borges de Sá

    2012-06-01

    Full Text Available Objective: To assess the knowledge and satisfaction of users of a Basic Health Unit about the strategy of embracement. Methods: Descriptive study with qualitative approach, carried out in a Basic Health Unit, Fortaleza, Brazil, where practical activities of the Education Program of Work for Health of the University of Fortaleza were performed. Fifty eight service users were involved, following inclusion criteria: being present during the data collection, age over 18, regardless of sex, and voluntary participation. Data collection occurred in December 2009, through semi-structured interview. The data associated with the identification of users were processed in Microsoft Office Excel 2007, being organizedstatistically in table. Data related to qualitative aspects were analyzed according to the technique of content analysis. Results: 56 (97% were women, with ages ranging between 21 and 40 years, 34 (59% were married and 53 (91% are literate. On family income, 55 (95%received less than two minimum salaries per month. In order to facilitate understanding the speech of users, these were evaluated from the perspective of two categories: knowledge about embracement and satisfaction with embracement. Conclusion: Users have a limited view of the significance and magnitude of the embracement to provide the care. Although satisfied with the service, respondents report as negative aspects: the shortage of professionals, the professional relationship with user impaired due to constant delays of the professional, and the dehumanization of care.

  20. JEDI Marine and Hydrokinetic Model: User Reference Guide

    Energy Technology Data Exchange (ETDEWEB)

    Goldberg, M.; Previsic, M.

    2011-04-01

    The Jobs and Economic Development Impact Model (JEDI) for Marine and Hydrokinetics (MHK) is a user-friendly spreadsheet-based tool designed to demonstrate the economic impacts associated with developing and operating MHK power systems in the United States. The JEDI MHK User Reference Guide was developed to assist users in using and understanding the model. This guide provides information on the model's underlying methodology, as well as the sources and parameters used to develop the cost data utilized in the model. This guide also provides basic instruction on model add-in features, operation of the model, and a discussion of how the results should be interpreted.

  1. Cross-National User Priorities for Housing Provision and Accessibility — Findings from the European innovAge Project

    Directory of Open Access Journals (Sweden)

    Maria Haak

    2015-03-01

    Full Text Available To develop an innovative information and communication technology (ICT tool intended to help older people in their search for optimal housing solutions, a first step in the development process is to gain knowledge from the intended users. Thus the aim of this study was to deepen the knowledge about needs and expectations about housing options as expressed and prioritized by older people, people ageing with disabilities and professionals. A participatory design focus was adopted; 26 people with a range of functional limitations representing the user perspective and 15 professionals with a variety of backgrounds, participated in research circles that were conducted in four European countries. An additional 20 experts were invited as guests to the different research circle meetings. Three themes illustrating cross-national user priorities for housing provision and accessibility were identified: “Information barrier: accessible housing”, “Information barrier: housing adaptation benefits”, and “Cost barrier: housing adaptations”. In conclusion, early user involvement and identification of cross-national differences in priorities and housing options will strengthen the development of a user-friendly ICT tool that can empower older people and people with disabilities to be more active consumers regarding housing provision.

  2. Cross-national user priorities for housing provision and accessibility--findings from the European innovAge Project.

    Science.gov (United States)

    Haak, Maria; Slaug, Björn; Oswald, Frank; Schmidt, Steven M; Rimland, Joseph M; Tomsone, Signe; Ladö, Thomas; Svensson, Torbjörn; Iwarsson, Susanne

    2015-03-02

    To develop an innovative information and communication technology (ICT) tool intended to help older people in their search for optimal housing solutions, a first step in the development process is to gain knowledge from the intended users. Thus the aim of this study was to deepen the knowledge about needs and expectations about housing options as expressed and prioritized by older people, people ageing with disabilities and professionals. A participatory design focus was adopted; 26 people with a range of functional limitations representing the user perspective and 15 professionals with a variety of backgrounds, participated in research circles that were conducted in four European countries. An additional 20 experts were invited as guests to the different research circle meetings. Three themes illustrating cross-national user priorities for housing provision and accessibility were identified: "Information barrier: accessible housing", "Information barrier: housing adaptation benefits", and "Cost barrier: housing adaptations". In conclusion, early user involvement and identification of cross-national differences in priorities and housing options will strengthen the development of a user-friendly ICT tool that can empower older people and people with disabilities to be more active consumers regarding housing provision.

  3. GEOSTATISTICS FOR WASTE MANAGEMENT: A USER'S MANUAL FOR THE GEOPACK (VERSION 1.0) GEOSTATISTICAL SOFTWARE SYSTEM

    Science.gov (United States)

    GEOPACK, a comprehensive user-friendly geostatistical software system, was developed to help in the analysis of spatially correlated data. The software system was developed to be used by scientists, engineers, regulators, etc., with little experience in geostatistical techniques...

  4. The User Experience

    Science.gov (United States)

    Schmidt, Aaron

    2010-01-01

    User experience (UX) is about arranging the elements of a product or service to optimize how people will interact with it. In this article, the author talks about the importance of user experience and discusses the design of user experiences in libraries. He first looks at what UX is. Then he describes three kinds of user experience design: (1)…

  5. User Innovation Management

    DEFF Research Database (Denmark)

    Kanstrup, Anne Marie; Bertelsen, Pernille

    User Innovation Management (UIM) is a method for fo-opereation with users in innovation projects. The UIM method emphasizes the practice of a participatorty attitude.......User Innovation Management (UIM) is a method for fo-opereation with users in innovation projects. The UIM method emphasizes the practice of a participatorty attitude....

  6. User Behavior Analytics

    Energy Technology Data Exchange (ETDEWEB)

    Turcotte, Melissa [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Moore, Juston Shane [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-02-28

    User Behaviour Analytics is the tracking, collecting and assessing of user data and activities. The goal is to detect misuse of user credentials by developing models for the normal behaviour of user credentials within a computer network and detect outliers with respect to their baseline.

  7. The User Experience

    Science.gov (United States)

    Schmidt, Aaron

    2010-01-01

    User experience (UX) is about arranging the elements of a product or service to optimize how people will interact with it. In this article, the author talks about the importance of user experience and discusses the design of user experiences in libraries. He first looks at what UX is. Then he describes three kinds of user experience design: (1)…

  8. Lung hyperinflation: foe or friend?

    Science.gov (United States)

    Eichinger, M; Walterspacher, S; Scholz, T; Tetzlaff, K; Röcker, K; Muth, C-M; Puderbach, M; Kauczor, H-U; Sorichter, S

    2008-10-01

    Breath-hold divers employ glossopharyngeal insufflation (GI) in order to prevent the lungs from compressing at great depth and to increase intrapulmonary oxygen stores, thus increasing breath-hold time. The presented case study shows the physiological data and dynamic magnetic resonance imaging (dMRI) findings of acute hyperinflation, deliberately induced by GI, in a breath-hold diver and discusses the current state of knowledge regarding the associated hazards of this unique competitive sport. Static and dynamic lung volumes and expiratory flows were within the normal range, with vital capacity and peak expiratory flow being higher than the predicted values. Airway resistance and diffusing capacity of the lung for carbon monoxide were normal. Static compliance was normal and increased five-fold with hyperinflation. dMRI revealed a preserved shape of the thorax and diaphragm with hyperinflation. A herniation of the lung beneath the sternum and enlargement of the costodiaphragmatic angle were additional findings during the GI manoeuvre. After expiration, complete resolution to baseline was demonstrated. Hyperinflation can be physiological and even protective under abnormal physical conditions in the sense of acute adaptation to deep breath-hold diving. Dynamic magnetic resonance imaging is adequate for visualisation of the sequence of the glossopharyngeal insufflation manoeuvre and the complete reversibility of deliberate hyperinflation.

  9. Electricity storage: Friend or foe of the networks?

    Science.gov (United States)

    Jamasb, Tooraj

    2017-06-01

    As storage technology progresses it offers a range of solutions and services to users and the electricity industry. A new study explores whether or not this will eventually lead to self-sufficient consumers and spell the end of the networks as we know them.

  10. Eye tracking in user experience design

    CERN Document Server

    Romano Bergstorm, Jennifer

    2014-01-01

    Eye Tracking for User Experience Design explores the many applications of eye tracking to better understand how users view and interact with technology. Ten leading experts in eye tracking discuss how they have taken advantage of this new technology to understand, design, and evaluate user experience. Real-world stories are included from these experts who have used eye tracking during the design and development of products ranging from information websites to immersive games. They also explore recent advances in the technology which tracks how users interact with mobile devices, large-screen displays and video game consoles. Methods for combining eye tracking with other research techniques for a more holistic understanding of the user experience are discussed. This is an invaluable resource to those who want to learn how eye tracking can be used to better understand and design for their users. * Includes highly relevant examples and information for those who perform user research and design interactive experi...

  11. Foreign Friends Join Spring Tea Picking

    Institute of Scientific and Technical Information of China (English)

    Rong; You

    2013-01-01

    <正>Foreign Friends Picking Spring Tea, one of the activities of the Fourth China Tea Festival, was held in Pujiang County, Sichuan Province on March 17. Pang Te Cheng, Singaporean Consul General in Chengdu, Komate Kamalanavin, Thai Consul General in Chengdu, and Claudia Spahl, German

  12. Participants in "Friends with Benefits" Relationships

    Science.gov (United States)

    Puentes, Jennifer; Knox, David; Zusman, Marty E.

    2008-01-01

    Analysis of survey data from 1013 undergraduates at a large southeastern university revealed that over half (51%) reported experience in a "friends with benefits" relationship. In comparing the background characteristics of participants with nonpartipants in a FWBR, ten statistically significant findings emerged. Findings included that…

  13. The Importance of Friends in Autobiographical Memory

    DEFF Research Database (Denmark)

    Antalikova, Radka; Hansen, Tia G. B.; Gulbrandsen, Knut Arild;

    Relatedness is a complex issue and it has been argued that developmental perspectives should complement cross-cultural comparisons. We noticed that cross-cultural studies of autobiographical memories tend to focus on early childhood and thus family, leaving the role of friends and school less exp...

  14. Friend Influence on Achievement during Middle Childhood

    Science.gov (United States)

    DeLay, Dawn

    2013-01-01

    This study was designed to investigate friend influence on academic achievement and task avoidance during middle childhood in a sample of 794 participants in 397 stable same-sex friendship dyads (205 girl dyads and 192 boy dyads) from four municipalities in Finland: two in Central Finland, one in Western Finland, and one in Eastern Finland.…

  15. Friend Flips: A Story Activity about Relationships

    Science.gov (United States)

    Szucs, Leigh; Reyes, Jovanni V.; Farmer, Jennifer; Wilson, Kelly L.; McNeill, Elisa Beth

    2015-01-01

    Adolescents are influenced by the type, length and quality of the connections shared with different people throughout their lifespan. Relationships with peers, friends, and adults help to shape knowledge, attitudes, and beliefs related to health. Recognizing healthy or unhealthy characteristics allow youth to strengthen relationships and…

  16. Friends of NSFC in Obama's Cabinet

    Institute of Scientific and Technical Information of China (English)

    Yuan Youxin

    2008-01-01

    @@ On 15 December,2008,the US President-Elect Obama Picked Steven Chu for Energy Secretary.Steven Chu is an old friend of NSFC.On May 4,1998,he attended a reception of Nobel Prize winners in Beijing hosted by the National Natural Science Foundation of China.The following photos were taken at the meeting.

  17. The most common friend first immunization

    Science.gov (United States)

    Nian, Fu-Zhong; Hu, Cha-Sheng

    2016-12-01

    In this paper, a standard susceptible-infected-recovered-susceptible(SIRS) epidemic model based on the Watts-Strogatz (WS) small-world network model and the Barabsi-Albert (BA) scale-free network model is established, and a new immunization scheme — “the most common friend first immunization” is proposed, in which the most common friend’s node is described as being the first immune on the second layer protection of complex networks. The propagation situations of three different immunization schemes — random immunization, high-risk immunization, and the most common friend first immunization are studied. At the same time, the dynamic behaviors are also studied on the WS small-world and the BA scale-free network. Moreover, the analytic and simulated results indicate that the immune effect of the most common friend first immunization is better than random immunization, but slightly worse than high-risk immunization. However, high-risk immunization still has some limitations. For example, it is difficult to accurately define who a direct neighbor in the life is. Compared with the traditional immunization strategies having some shortcomings, the most common friend first immunization is effective, and it is nicely consistent with the actual situation. Project supported by the National Natural Science Foundation of China (Grant No. 61263019), the Program for International Science and Technology Cooperation Projects of Gansu Province, China (Grant No. 144WCGA166), and the Program for Longyuan Young Innovation Talents and the Doctoral Foundation of Lanzhou University of Technology, China.

  18. LET BOOKS BE OUR GOOD FRIENDS

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    Books are our friends because they are bridges to knowledge. Knowledge isvaluable because it enriches our life and brings us happiness.Almost all great men in the history of mankind loved books. We have every reason to believe it is the knowledge in books that led them to success.

  19. Chinese Friendly Personages’ Delegation Visits Vietnam

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    <正>A 50-member "Meeting at Uncle Ho’s Hometown" Chinese friendly personages’delegation led by Wang Yunze, vice president of the China-Vietnam Friendship Association (CVFA), paid a visit to Vietnam from May 15 to 23. Nguyen Minh Triet, Vietnamese president;

  20. Interactive and Symbolic Data Dependence AnalysisBased on Ranges of Expressions

    Institute of Scientific and Technical Information of China (English)

    杨博; 郑丰宙; 王鼎兴; 郑纬民

    2002-01-01

    Traditional data dependence testing algorithms have become very accurate and efficient for simple subscript expressions, but they cannot handle symbolic expressions because of the complexity of data-flow and lack of the semantic information of variables in programs. In this paper, a range-based testing and query approach, called DDTQ, is proposed to eliminate data dependence between array references with symbolic subscripts. DDTQ firstly extracts data dependence information from the symbolic subscripts, a testing algorithm is then used to disprove the dependence based on the ranges of expressions. The assumed dependence that cannot be handled by the disprover will be converted into simple questions by a question engine so that the compiler can solve them by user interaction in a friendly way. The experiment on perfect benchmarks indicates that DDTQ is effective in improving the parallelizing capability of the compiler.

  1. Designing end-user interfaces

    CERN Document Server

    Heaton, N

    1988-01-01

    Designing End-User Interfaces: State of the Art Report focuses on the field of human/computer interaction (HCI) that reviews the design of end-user interfaces.This compilation is divided into two parts. Part I examines specific aspects of the problem in HCI that range from basic definitions of the problem, evaluation of how to look at the problem domain, and fundamental work aimed at introducing human factors into all aspects of the design cycle. Part II consists of six main topics-definition of the problem, psychological and social factors, principles of interface design, computer intelligenc

  2. Attempt on construction of human friendly man-machine interface. Study and apply about human communication; Human friendly na man machine interface kochiku no kokoromi. Ningen no communication no kento to sono oyo

    Energy Technology Data Exchange (ETDEWEB)

    Tatsuno, J. [Tokyo University of Agriculture, Tokyo (Japan); Kokubo, Y.; Matsumura, I.; Kobayashi, H. [Hosei University, Tokyo (Japan)

    1998-04-01

    This paper describes an attempt on a construction way of human friendly man-machine interface. At first, we do a simple experiment to find out the characteristic of human verbal communication. From the experimental results, we get some rules in case in human verbal communication. We construct the man-machine interface which is based on these rules. Through teaching process, we examine our verbal communication interface comparing with conventional interfaces. From this comparison, we recognize that the verbal communication interface is valid to construct the user-friendly man-machine interface. 12 refs., 9 figs., 2 tabs.

  3. Approaches for user profile Investigation in Orkut Social Network

    CERN Document Server

    Singh, Rajni Ranjan

    2009-01-01

    Internet becomes a large and rich repository of information about us as individually. Any thing form user profile information to friends links the user subscribes to are reflection of social interactions as user has in real worlds. Social networking has created new ways to communicate and share information. Social networking websites are being used regularly by millions of people, and it now seems that social networking will be an enduring part of everyday life. Social networks such as Orkut, Bebo, MySpace, Flickr, Facebook, Friendster and LinkedIn, have attracted millions of internet user who are involved in bogging, participatory book reviewing, personal networking and photo sharing. Social network services are increasingly being used in legal and criminal investigations. Information posted on sites such as Orkut and Facebook has been used by police, probation, and university officials to prosecute users of said sites. In some situations, content posted on web social network has been used in court. In the p...

  4. Real-time fMRI pattern decoding and neurofeedback using FRIEND: an FSL-integrated BCI toolbox.

    Directory of Open Access Journals (Sweden)

    João R Sato

    Full Text Available The demonstration that humans can learn to modulate their own brain activity based on feedback of neurophysiological signals opened up exciting opportunities for fundamental and applied neuroscience. Although EEG-based neurofeedback has been long employed both in experimental and clinical investigation, functional MRI (fMRI-based neurofeedback emerged as a promising method, given its superior spatial resolution and ability to gauge deep cortical and subcortical brain regions. In combination with improved computational approaches, such as pattern recognition analysis (e.g., Support Vector Machines, SVM, fMRI neurofeedback and brain decoding represent key innovations in the field of neuromodulation and functional plasticity. Expansion in this field and its applications critically depend on the existence of freely available, integrated and user-friendly tools for the neuroimaging research community. Here, we introduce FRIEND, a graphic-oriented user-friendly interface package for fMRI neurofeedback and real-time multivoxel pattern decoding. The package integrates routines for image preprocessing in real-time, ROI-based feedback (single-ROI BOLD level and functional connectivity and brain decoding-based feedback using SVM. FRIEND delivers an intuitive graphic interface with flexible processing pipelines involving optimized procedures embedding widely validated packages, such as FSL and libSVM. In addition, a user-defined visual neurofeedback module allows users to easily design and run fMRI neurofeedback experiments using ROI-based or multivariate classification approaches. FRIEND is open-source and free for non-commercial use. Processing tutorials and extensive documentation are available.

  5. User evaluation in practice

    DEFF Research Database (Denmark)

    Krogstrup, Hanne Kathrine

    2004-01-01

    The BIKVA-model (brugerinddragelse i kvalitetsvurdering) or in english UPQA (User Participation in Quality Assessment) are presented......The BIKVA-model (brugerinddragelse i kvalitetsvurdering) or in english UPQA (User Participation in Quality Assessment) are presented...

  6. User Privacy and Empowerment:

    DEFF Research Database (Denmark)

    Dhotre, Prashant Shantaram; Olesen, Henning; Khajuria, Samant

    2017-01-01

    of personal information and its manage-ment. Thus, empowering users and enhancing awareness are essential to compre-hending the value of secrecy. This paper also introduced latest advances in the domain of privacy issues like User Managed Access (UMA) can state suitable requirements for user empowerment...... and will cater to redefine the trustworthy relationship between service providers and users. Subsequently, this paper con-cludes with suggestions for providing empowerment to the user and developing user-centric, transparent business models.......Today, the service providers are capable of assembling a huge measure of user information using Big data techniques. For service providers, user infor-mation has become a vital asset. The present business models are attentive to collect extensive users’ information to extract useful knowledge...

  7. Environment-friendly drilling operation technology

    Science.gov (United States)

    Luo, Huaidong; Jing, Ning; Zhang, Yanna; Huang, Hongjun; Wei, Jun

    2017-01-01

    Under the circumstance that international safety and environmental standards being more and more stringent, drilling engineering is facing unprecedented challenges, the extensive traditional process flow is no longer accepted, the new safe and environment-friendly process is more suitable to the healthy development of the industry. In 2015, CNPCIC adopted environment-friendly drilling technology for the first time in the Chad region, ensured the safety of well control, at the same time increased the environmental protection measure, reduced the risk of environmental pollution what obtain the ratification from local government. This technology carries out recovery and disposal of crude oil, cuttings and mud without falling on the ground. The final products are used in road and well site construction, which realizes the reutilization of drilling waste, reduces the operating cost, and provides a strong technical support for cost-cutting and performance-increase of drilling engineering under low oil price.

  8. Creating an Asthma-Friendly School

    Centers for Disease Control (CDC) Podcasts

    2007-11-08

    This podcast features real-life success stories of students with asthma who, thanks to their schools' implementation of asthma-friendly policies and programs, now have their asthma under control.  Created: 11/8/2007 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP), Division of Adolescent and School Health (DASH).   Date Released: 5/20/2008.

  9. Environmentally-friendly practices in hotels

    OpenAIRE

    Miriam Mbasera; Engelina Du Plessis; Melville Saayman; Martinette Kruger

    2016-01-01

    Orientation: There has been a growing concern for a ‘green’ hotel in the view of customers as they experience an increased awareness of environmental damage and excessive consumption of goods, energy and water.Research purpose: To determine the environmentally-friendly practices in hotels in Zimbabwe and South Africa and establish the contribution that hotels are making towards mitigation of the negative environmental effects.Motivation for the study: Currently, the world is facing environmen...

  10. CAD Instructor Designs Eco-Friendly Shed

    Science.gov (United States)

    Schwendau, Mark

    2013-01-01

    Dissatisfied with the options offered by big box stores--and wanting to save some money and go as green as possible--the author puts his design and construction skills to good use. In this article, he shares how he designed and built an eco-friendly shed. He says he is very pleased with the results of working with his own design, reducing waste,…

  11. Eco-friendly location of small hydropower

    OpenAIRE

    O'Hanley, J.R.

    2016-01-01

    We address the problem of locating small hydropower dams in an environmentally friendly manner. We propose the use of a multi-objective optimization model to maximize total hydropower production, while limiting negative impacts on river connectivity. Critically, we consider the so called “backwater effects” that dams have on power generation at nearby upstream sites via changes in water surface profiles. We further account for the likelihood that migratory fish and other aquatic species can s...

  12. CAD Instructor Designs Eco-Friendly Shed

    Science.gov (United States)

    Schwendau, Mark

    2013-01-01

    Dissatisfied with the options offered by big box stores--and wanting to save some money and go as green as possible--the author puts his design and construction skills to good use. In this article, he shares how he designed and built an eco-friendly shed. He says he is very pleased with the results of working with his own design, reducing waste,…

  13. Transparent User Authentication

    CERN Document Server

    Clarke, Nathan

    2011-01-01

    This groundbreaking text examines the problem of user authentication from a completely new viewpoint. Rather than describing the requirements, technologies and implementation issues of designing point-of-entry authentication, the book introduces and investigates the technological requirements of implementing transparent user authentication -- where authentication credentials are captured during a user's normal interaction with a system. This approach would transform user authentication from a binary point-of-entry decision to a continuous identity confidence measure. Topics and features: discu

  14. Disaster-friendly sundanese traditional building construction

    Science.gov (United States)

    Maknun, J.; Busono, T.; Nuryanto

    2016-04-01

    Indonesia is one country that is highly prone to earthquakes because it is located at the juncture of four tectonic plates, namely the Asian continental shelf, the continental shelf of Australia, the Indian Ocean plate and the Pacific plate. In the southern and eastern parts of Indonesia there is a volcanic belt that extends from the island of Sumatra, Java and Nusa south eastern Sulawesi, the sides in the form of old volcanic mountains and the lowlands are mostly dominated by swamps. The condition of potential and proneness to disasters such as volcanic eruptions, earthquakes, tsunamis, floods, and landslides. Indonesian society have a local knowledge for facing disasters. Local communities in particular areas have local knowledge for facing disasters. Such knowledge is commonly kept by members of the communities and applied to their environments, including houses. This research aims to describe disaster-friendly Sundanese traditional building construction. It employs the evaluation method, by comparing Sundanese traditional house construction to the standards of disaster-friendly construction. The results indicate that the Sundanese traditional building constructions have been qualified as disaster-friendly buildings.

  15. A novel R-package graphic user interface for the analysis of metabonomic profiles

    Directory of Open Access Journals (Sweden)

    Villa Palmira

    2009-10-01

    Full Text Available Abstract Background Analysis of the plethora of metabolites found in the NMR spectra of biological fluids or tissues requires data complexity to be simplified. We present a graphical user interface (GUI for NMR-based metabonomic analysis. The "Metabonomic Package" has been developed for metabonomics research as open-source software and uses the R statistical libraries. Results The package offers the following options: Raw 1-dimensional spectra processing: phase, baseline correction and normalization. Importing processed spectra. Including/excluding spectral ranges, optional binning and bucketing, detection and alignment of peaks. Sorting of metabolites based on their ability to discriminate, metabolite selection, and outlier identification. Multivariate unsupervised analysis: principal components analysis (PCA. Multivariate supervised analysis: partial least squares (PLS, linear discriminant analysis (LDA, k-nearest neighbor classification. Neural networks. Visualization and overlapping of spectra. Plot values of the chemical shift position for different samples. Furthermore, the "Metabonomic" GUI includes a console to enable other kinds of analyses and to take advantage of all R statistical tools. Conclusion We made complex multivariate analysis user-friendly for both experienced and novice users, which could help to expand the use of NMR-based metabonomics.

  16. User Requirements for Wireless

    DEFF Research Database (Denmark)

    technologies or software has been developed. A variety of user requirements are provided illustrating the effect of changing the targeted user group with respect to age,; to the context and the different technologies or software as well as to the difference in viewpoint on ways of involving users...

  17. User Demographics for Embodiment Customization

    Energy Technology Data Exchange (ETDEWEB)

    Cowell, Andrew J.; Stanney, Kay M.

    2002-11-15

    Attempts at interface agent personalization are usually aimed at helping the user perform a task or service. For example,scheduling of appointments, inspection of messages, discovering items of interest and different forms of negotiation. While this is very noble undertaking, it makes assumptions about the level of trust and credibility a user may place in such an agent in a realworld setting. If Microsoft's experiments in social user interfaces teach us anything, it is that a ''one size fits all'' solution does not truly engage the user and encourage reuse. This ''relationship management'' between the user and the character begins when the two first meet. As with human-human relationships, first impressions are essential. Instead of looking at the functional aspects of the relationship, we believe the characters embodiment is the best place to start the personalization process. We describe a study in which participants from several different age ranges,genders and ethnic groups were asked their preference of anthropomorphic character, based on a cooperative computer task. We found that participants generally selected characters from the same ethic group as themselves and that almost all participants selected a young character (instead of a middle aged or elderly character). No significant preference was found for character gender.

  18. CaMath user`s guide

    Energy Technology Data Exchange (ETDEWEB)

    Cha, Ben-chin; Daly, B.

    1994-07-13

    CaMath is an external Mathematica package which can be loaded into Mathematica by a user. CaMath consists of a special set of channel access functions which provides the Mathematica users with easy and flexible access of channel information across the IOC networks. It also provides a complete set of process variable event monitoring functions. The available functions for CaMath, their functionality, and their syntax are described herein. This document also gives examples how a Mathematica user can interface to channel access devices. It is assumed that the user is already familiar with using Mathematica. Few examples of Mathematica module of using CaMath functions are also given in this document.

  19. More Colleges Are Adding Family-Friendly Benefits

    Science.gov (United States)

    Wilson, Robin

    2008-01-01

    Results of a new survey of family-friendly benefits by the Center for the Education of Women at the University of Michigan at Ann Arbor show that stopping the tenure clock has become the most common family-friendly benefit in higher education, following paid maternity leave. Other family-friendly policies that top the list in academe allow…

  20. Ethnic Differences among Friend Networks Later in Life

    Science.gov (United States)

    Kang, Hyunsook; Hebert, Corie

    2014-01-01

    This study seeks to broaden the understanding of friend relationships in older adults and the differences in those friend relationships among various ethnic groups. Secondary data from the National Social Life, Health and Aging Project (NSHAP) was analyzed to test the hypothesis that Caucasian older adults have stronger friend networks than older…

  1. Maternal Affection Moderates Friend Influence on Schoolwork Engagement

    Science.gov (United States)

    Marion, Donna; Laursen, Brett; Kiuru, Noona; Nurmi, Jari-Erik; Salmela-Aro, Katariina

    2014-01-01

    This study investigated friend influence over adolescent schoolwork engagement in 160 same-sex friend dyads (94 female dyads and 66 male dyads). Participants were approximately 16 years of age at the outset. Each friend described his or her own schoolwork engagement, school burnout, and perceptions of maternal affection. The results revealed that…

  2. Friends of Survivors: The Community Impact of Unwanted Sexual Experiences

    Science.gov (United States)

    Banyard, Victoria L.; Moynihan, Mary M.; Walsh, Wendy A.; Cohn, Ellen S.; Ward, Sally

    2010-01-01

    Since sexual assault survivors are most likely to disclose their experiences to a friend; prevention efforts increasingly focus on friends as informal helpers. The current study examined friends' perceptions of the disclosure experience. Undergraduates (N = 1,241) at the University of New Hampshire completed a shortened version of the Ahrens and…

  3. Associations between friends' disordered eating and muscle-enhancing behaviors.

    Science.gov (United States)

    Eisenberg, Marla E; Wall, Melanie; Shim, Jin Joo; Bruening, Meg; Loth, Katie; Neumark-Sztainer, Dianne

    2012-12-01

    Dieting, unhealthy weight control and muscle-enhancing behaviors are common among adolescents: friends are a probable source of influence on these behaviors. The present study uses data provided by nominated friends to examine associations between friends' disordered eating and muscle-enhancing behaviors and participants' own behaviors in a diverse sample of American youth. Male and female adolescents (mean age = 14.4) completed surveys and identified their friends from a class roster; friends' survey data were then linked to each participant. Participants (N = 2126) who had at least one nominated friend were included in the analytic sample. Independent variables were created using the same weight control and muscle-enhancing behaviors reported by nominated friends, and were used in logistic regression models to test associations between participants' and their friends' behaviors, stratified by gender. Results indicated that dieting, disordered eating and muscle-enhancing behaviors were common in this sample, and selected friends' behaviors were associated with the same behaviors in participants. For example, girls whose friends reported extreme weight control behaviors had significantly greater odds of using these behaviors than girls whose friends did not report these same behaviors (OR = 2.39). This research suggests that friends' weight- and shape-related behaviors are a feature of social relationships, and is the first report demonstrating these associations for muscle-enhancing behaviors. Capitalizing on the social element may be important to the development of increasingly effective intervention and prevention programs.

  4. Constraints in the Adoption of Eco Friendly Conservation Practices

    Directory of Open Access Journals (Sweden)

    L. Murali Krishnan

    2016-05-01

    Insect pest and diseases management, Lack of awareness of agro environmental problems and farmer’s attitude towards the Eco Friendly Conservation Practices are the major constraints in the adoption of Eco Friendly Conservation Practices.The study suggests educational, extension & training strategies for fostering the adopted of ECO friendly Conservation Practices.

  5. DOSFAC2 user`s guide

    Energy Technology Data Exchange (ETDEWEB)

    Young, M.L.; Chanin, D.

    1997-12-01

    This document describes the DOSFAC2 code, which is used for generating dose-to-source conversion factors for the MACCS2 code. DOSFAC2 is a revised and updated version of the DOSFAC code that was distributed with version 1.5.11 of the MACCS code. included are (1) an overview and background of DOSFAC2, (2) a summary of two new functional capabilities, and (3) a user`s guide. 20 refs., 5 tabs.

  6. eProject User Experience: The Reality

    Directory of Open Access Journals (Sweden)

    John Sandler

    2010-11-01

    Full Text Available Corporate eProjects have become fast-paced and increasingly demanding. More often than not, problems and challenges readily surface within technology projects. These can often stem from poor usability and user experience aspects of the development process, together with lack of adequate communications plans and strategies. Successful forward planning and succinct on-going communication of development and testing processes is critical. Clear communications across the range of impacted user work groups, together with the project team, ensuring an understanding of all roles in the development process is vital. Understanding the need to engage expert users and representatives from the impacted user groups is also critical. This paper and associated presentation will look at what can happen in the real world, when even highly detailed project planning can be undermined by a lack of communications, understanding and unsatisfactory project team user experience. In effect, the user experience of project teams.

  7. Range Tracing

    OpenAIRE

    Jenke, Philipp; Huhle, Benjamin

    2010-01-01

    In this report, we tackle the problem of merging an arbitrary number of range scans (depth images) into a single surface mesh. The mesh-based representation is superior to point-based approaches since it contains important connectivity information. Most previous mesh-based merge methods, however, lose surface details by using simplifying intermediate surface representations (e.g.\\ implicit functions). Such details are essential for further processing steps, especially for feature-preserving r...

  8. Information processing speed in ecstasy (MDMA) users.

    Science.gov (United States)

    Wareing, Michelle; Fisk, John E; Montgomery, Catharine; Murphy, Philip N; Chandler, Martin D

    2007-03-01

    Previous research draws parallels between ecstasy-related and age-related deficits in cognitive functioning. Age-related impairments in working memory have been attributed to a slow down in information processing speed. The present study compared 29 current ecstasy users, 10 previous users and 46 non-users on two tests measuring information processing speed and a computation span task measuring working memory. Results showed that ecstasy users performed worse than non-ecstasy users in the letter comparison task although the overall difference was not significant (p=0.089). Results from the pattern recognition task showed that current ecstasy users produced significantly more errors than the other two groups (pecstasy users produced significantly more errors than non-ecstasy users (pecstasy using groups performing significantly worse than non-users on the computation span measure (pmechanism responsible for impairments in the computation span measure is not the same as that in elderly adults where processing speed generally removes most of the age-related variance. Also of relevance is the fact that the ecstasy users reported here had used a range of other drugs making it difficult to unambiguously attribute the results obtained to ecstasy use.

  9. Best friends: the role of confidantes in older women's health.

    Science.gov (United States)

    Moremen, Robin D

    2008-01-01

    This article explores personal, network, and community contexts in older women's friendships and health. Twenty-six older women (mean age, 67; range 55-85 years) in San Francisco were asked to choose the one individual to whom they felt the closest and then discuss how this individual contributed to their health. Their choices were numerous, diverse, contextual, and circumstantial. Other women were chosen most often; however, this belies the complexity of their choices. Confidants were chosen primarily for expressive reasons, but instrumental reasons proved important too, particularly for lower class women. Older women called upon their closest ties with physical, social, and emotional problems; they were less likely to call upon them with mental, financial, or spiritual concerns. Family members were preferred to friends for direct caregiving; however, some older women felt they would call upon their friends as well. Confidants kept older women healthy by offering advice and encouragement about diet and exercise; by providing meals and transportation; by laughing, talking, and joking with them; by keeping them happy and feeling good about themselves; and, on rare occasions, by offering spiritual guidance. Practical and policy considerations of their choices were discussed.

  10. International user studies

    DEFF Research Database (Denmark)

    Nielsen, Lene; Madsen, Sabine; Jensen, Iben;

    in Sydhavnen, and it is funded by InfinIT. Based on a qualitative interview study with 15 user researchers from 11 different companies, we have investigated how companies collect and present data about users on international markets. Key findings are: Companies do not collect data about end users in all....../region. The preferred data collection method is field studies. If possible, user researchers choose to go to the field themselves to gain rich insights and to control the data collection process. The main insights companies gain from international user studies are (1) that there are many similarities among end users...... across nationalities and (2) that it often is more important to focus on and take differences in market conditions into account than national culture per se. Companies are in the process of finding out how best to present the insights about international end users to their employees. However, so far...

  11. The overdensity and masses of the friends-of-friends halos and universality of the halo mass function

    CERN Document Server

    More, Surhud; Dalal, Neal; Gottlöber, Stefan

    2011-01-01

    The friends-of-friends algorithm (hereafter, FOF) is a percolation algorithm which is routinely used to identify dark matter halos from N-body simulations. We use results from percolation theory to show that the boundary of FOF halos does not correspond to a single density threshold but to a range of densities close to a critical value that depends upon the linking length parameter, b. We show that for the commonly used choice of b = 0.2, this critical density is equal to 81.62 times the mean matter density. Consequently, halos identified by the FOF algorithm enclose an average overdensity which depends on their density profile (concentration) and therefore changes with halo mass contrary to the popular belief that the average overdensity is ~180. We derive an analytical expression for the overdensity as a function of the linking length parameter b and the concentration of the halo. Results of tests carried out using simulated and actual FOF halos identified in cosmological simulations show excellent agreemen...

  12. Influence of friends on children's physical activity: a review.

    Science.gov (United States)

    Maturo, Claire C; Cunningham, Solveig A

    2013-07-01

    We examined evidence for friendship influences on children's physical activity (PA) through systematic searches of online databases in May 2012. We identified 106 studies (25 qualitative) published in English since 2000 that analyzed indicators of friendship influences (e.g., communication about PA, friends' PA, and PA with friends) among persons younger than 19 years. Children's PA was positively associated with encouragement from friends (43 of 55 studies indicating a positive relationship), friends' own PA (30/35), and engagement with friends in PA (9/10). These findings are consistent with friends influencing PA, but most studies did not isolate influence from other factors that could explain similarity. Understanding friendship influences in childhood can facilitate the promotion of lifelong healthy habits. PA with friends should be considered in health promotion programs.

  13. To José Pereira Lages, our friend and colleague

    CERN Multimedia

    2005-01-01

    It was with great sadness that we learnt of the accidental demise of our colleague, José Pereira Lages, whilst he was transporting equipment for the LHC. José was the team leader for the LHC's general services at points 1 and 8, working on behalf of the firm DBS Transports. Determined and receptive, always ready to help those around him, he always did his best in his work. His smile, his kindness and his professionalism made him somebody who was unanimously appreciated, whether it was by his colleagues at DBS, his colleagues at CERN or any of the CERN users that he encountered. He leaves behind a large gap in our midst and we will all miss him. We will be reminded of his smile in this picture from the last issue of the Bulletin, taken to celebrate his win in the French Championships for fork-lift truck unloading. It was only a few days ago that we were so happy and proud of him, looking forward, in our minds, to the future competitions that lay ahead. We share the grief of his family and all his friend...

  14. Bio-inspired color sketch for eco-friendly printing

    Science.gov (United States)

    Safonov, Ilia V.; Tolstaya, Ekaterina V.; Rychagov, Michael N.; Lee, Hokeun; Kim, Sang Ho; Choi, Donchul

    2012-01-01

    Saving of toner/ink consumption is an important task in modern printing devices. It has a positive ecological and social impact. We propose technique for converting print-job pictures to a recognizable and pleasant color sketches. Drawing a "pencil sketch" from a photo relates to a special area in image processing and computer graphics - non-photorealistic rendering. We describe a new approach for automatic sketch generation which allows to create well-recognizable sketches and to preserve partly colors of the initial picture. Our sketches contain significantly less color dots then initial images and this helps to save toner/ink. Our bio-inspired approach is based on sophisticated edge detection technique for a mask creation and multiplication of source image with increased contrast by this mask. To construct the mask we use DoG edge detection, which is a result of blending of initial image with its blurred copy through the alpha-channel, which is created from Saliency Map according to Pre-attentive Human Vision model. Measurement of percentage of saved toner and user study proves effectiveness of proposed technique for toner saving in eco-friendly printing mode.

  15. DEEP WEB USERS DEANONIMIZATION SYSTEM

    OpenAIRE

    AVDOSHIN S.M.; LAZARENKO A.V.

    2016-01-01

    Privacy enhancing technologies (PETs) are ubiquitous nowadays. They are beneficial for a wide range of users: for businesses, journalists, bloggers, etc. However, PETs are not always used for legal activity. There a lot of anonymous networks and technologies which grants anonymous access to digital resources. The most popular anonymous networks nowadays is Tor. Tor is a valuable tool for hackers, drug and gun dealers. The present paper is focused on Tor users’ deanonimization using out-of-the...

  16. GPS User Equipment Performance Evaluation.

    Science.gov (United States)

    1979-11-01

    simulation of range dynamics of the satellite/user paths. The JGA provides four CW signals aid a I’N modulated RF signal so as to simulate up to 5 jummers...VN e (PN) 4 VE e (PE) ViH e (PCT) VN e (PE) - VE e (PN) e (VAT)= VN e (VN) 4 VE e (VE) VH e (VCT)= V e (V) - VE e (VN) V H For the true North (TN

  17. Can we be (and stay) friends? Remaining friends after dissolution of a romantic relationship.

    Science.gov (United States)

    Bullock, Melinda; Hackathorn, Jana; Clark, Eddie M; Mattingly, Brent A

    2011-01-01

    Although many individuals report being friends with their ex-romantic partners (Wilmot, Carbaugh, & Baxter, 1985), the literature regarding post-romantic friendships is very limited. We investigated whether satisfaction in the dissolved romantic relationship could predict post-romantic friendships and friendship maintenance. We found that the more satisfied individuals were during the dissolved romance, the more likely they were to remain friends and the more likely they were to engage in friendship maintenance behaviors. We also found that friendship maintenance fully mediated the association between past romantic satisfaction and current friendship satisfaction.

  18. Befriending Risky Peers: Factors Driving Adolescents' Selection of Friends with Similar Marijuana Use.

    Science.gov (United States)

    de la Haye, Kayla; Green, Harold D; Pollard, Michael S; Kennedy, David P; Tucker, Joan S

    2015-10-01

    Adolescents often befriend peers who are similar to themselves on a range of demographic, behavioral, and social characteristics, including substance use. Similarities in lifetime history of marijuana use have even been found to predict adolescent friendships, and we examine whether this finding is explained by youth's selection of friends who are similar on a range of more proximate, observable characteristics that are risk factors for marijuana use. Using two waves of individual and social network data from two high schools that participated in Add Health (N = 1,612; 52.7% male), we apply longitudinal models for social networks to test whether or not several observable risky attributes (psychological, behavioral, and social) predict adolescent friendship choices, and if these preferences explain friend's similarities on lifetime marijuana use. Findings show that similarities on several risk factors predict friendship choices, however controlling for this, the preference to befriend peers with a similar history of marijuana use largely persists. The results highlight the range of social selection processes that lead to similarities in marijuana use among friends and larger peer groups, and that also give rise to friendship groups whose members share similar risk factors for substance use. Friends with high "collective risk" are likely to be important targets for preventing the onset and social diffusion of substance use in adolescents.

  19. Being Fat and Friendly is Not Enough

    CERN Document Server

    Har-Peled, Sariel

    2009-01-01

    We show that there is no $(1+\\eps)$-approximation algorithm for the problem of covering points in the plane by minimum number of fat triangles of similar size (with the minimum angle of the triangles being close to 45 degrees). Here, the available triangles are prespecified in advance. Since a constant factor approximation algorithm is known for this problem \\cite{cv-iaags-07}, this settles the approximability of this problem. We also investigate some related problems, including cover by friendly fat shapes, and independent set of triangles in three dimensions.

  20. A customer-friendly Space Station

    Science.gov (United States)

    Pivirotto, D. S.

    1984-01-01

    This paper discusses the relationship of customers to the Space Station Program currently being defined by NASA. Emphasis is on definition of the Program such that the Space Station will be conducive to use by customers, that is by people who utilize the services provided by the Space Station and its associated platforms and vehicles. Potential types of customers are identified. Scenarios are developed for ways in which different types of customers can utilize the Space Station. Both management and technical issues involved in making the Station 'customer friendly' are discussed.

  1. Pragmatic Analysis on Verbal Humor in Friends

    Institute of Scientific and Technical Information of China (English)

    王芳

    2009-01-01

    As a nature of humanity, humor is a way of communication peculiar to human beings. Verbal humor is a cate-gory of humor which is used to express humorist ideas through language, and siteom as a unique comedy performance is an important carrier of humor. This paper applies some basic pragnmtic theories, such as Cooperative Principles (CP) and Relevance Theory(RT), to analyze the verbal humor in American popular situational comedy Friends, aiming to explore the generation mechanism of English humor. And then a better understanding and appreciation of English humor for English learners can be achieved.

  2. Characteristics of Hostile and Friendly Takeover Targets

    OpenAIRE

    Randall Morck; Andrei Shleifer; Vishny, Robert W.

    1987-01-01

    Compared to an average Fortune 500 firm, a target of a hostile takeover is smaller, older, has a lower Tobin's Q, invests less of its income, and is growing more slowly. The low Q seems to be an industry-specific rather than a firm-specific effect. In addition, a hostile target is less likely to be run by a member of the founding family, and has lower officer ownership, than the average firm. In contrast, a target of a friendly acquisitions is smaller and younger than an average Fortune 500 f...

  3. Synthesis of Environmentally Friendly Magnesium Linoleate Detergent

    Institute of Scientific and Technical Information of China (English)

    Wang Yonglei; Li Haiyun; Fang Hongxia; Ni Zhifei; Zhao Lele

    2014-01-01

    This paper mainly covers a method for preparing a highly alkaline magnesium linoleate solution with a total base number (TBN) value of 328 mg KOH/g using linoleic acid as the biodegradable raw material, which can substitute for traditional lubricant detergents as an environmentally friendly detergent. Reaction conditions, including the molar ratio of magnesium oxide to linoleic acid, the molar ratio of methanol to magnesium oxide, the carbonation temperature, the molar ratio of water to magnesium oxide, the lfow rate of CO2 gas and the duration for injection of CO2 to magnesium oxide sys-tem, were optimized.

  4. How to win friends and influence people

    CERN Document Server

    Carnegie, Dale

    2010-01-01

    For more than sixty years the rock-solid, time-tested advice in this book has carried thousands of now famous people up the ladder of success in their business and personal lives. With more than fifteen million copies sold, How to Win Friends and Influence People is one of the best known motivational books in history, with proven advice for achieving success in life. You’ll learn: three fundamental techniques in handling people; six ways to make people like you; twelve ways to win people to you way of thinking; nine ways to change people without arousing resentment; and much, much more!

  5. The Gemini Science User Support Department: A community-centered approach to user support

    Science.gov (United States)

    Chené, André-Nicolas; Thomas-Osip, Joanna

    2016-01-01

    The Gemini Science User Support Department (SUSD) was formed a little more than a year ago to create a collaborative community of users and staff and to consolidate existing post-observing support throughout the observatory for more efficient use of resources as well as better visibility amongst our user community. This poster is an opportunity to exchange ideas about how Gemini can improve your experience while working with the Observatory and present details about new avenues of post-observing support coming soon. We encourage your feedback at any time.Shortly after its creation, the SUSD conducted a complete revision of the communication cycle between Gemini and its community of researchers. The cycle was then revisited from the perspective of an astronomer interested in using Gemini for their research. This exercise led to a series of proposed changes that are currently under development, and the implementation of a sub-selection is expected in 2016, including the following. (1) Email notifications: Gemini users will receive new forms of email communications that are more instructive and tailored to their program. The objective is to direct the users more efficiently toward the useful links and documentation all along the lifecycle of the program, from phaseII to after the data are completely reduced. (2) HelpDesk system: The HelpDesk will become more user-friendly and transparent. (3) Webpages: The organization of the Gemini webpages will be redesigned to optimize navigation; especially for anything regarding more critical periods likes phaseIs and phaseIIs. (4) Data Reduction User Forum: Following recommendations from Gemini users, new capabilities were added to the forum, like email notifications, and a voting system, in order to make it more practical. This forum's objective is to bring the Gemini community together to exchange their ideas, thoughts, questions and solutions about data reduction, a sort of Reddit, StackOverflow or Slashdot for Gemini data.

  6. User-friendly websites in the eyes of young and old people

    NARCIS (Netherlands)

    Loos, E.F.; Mante-Meijer, E.A.

    2009-01-01

    Do elderly people really navigate websites in a different way than younger people do? Or are the differences within this group (such as those due to gender, education, computer experience and cultural background) bigger then differences between younger and older people? This paper first discusses us

  7. User-Friendly, Syntax Directed Input to a Computer Aided Design System.

    Science.gov (United States)

    1983-06-01

    indepen- dern-. oblems arise in both compu:er aided design and in software development as a result of multipla types cf computz , mUtiple languages...Base CONLAN. Ease CONLAN is defined cy three i- ms , a set of object types and cperations, syntax, and a comPuta-IoL model. It is defined with Primitive...ycsjum on Computer Hardware= DescrT:--c-: -Lanquaqes. ~ p. =-3’EEET73 28. H1Il, F. J., and Petezzcn, J. R., DjZt4- S Lt-= Ms : Hardware O~gan iza,,i.n cand

  8. PySCIs: a user friendly Python tool to quickly applying Small Circle methods

    Science.gov (United States)

    Calvín, Pablo; José Villalaín, Juan; Casas, Antonio; Torres, Sara

    2017-04-01

    Small Circle (SC) methods are common tools in paleomagnetic working on synfolding paleomagnetic components. These methods have a twofold applicability. On one hand, the Small Circle Intersection (SCI) method allows obtaining the local remagnetization direction and on the other the SCs can be used to restitute the attitude of the sedimentary beds at the moment of the remagnetization acquisition. The bases of the SCI method are as follows. (i) The paleomagnetic direction for each site follows a path which draws a SC under progressive untinting of the beds; this SC links the paleomagnetic direction before and after the tectonic correction. (ii) Considering that the beds have been deformed only by tilting around the bedding strike, the remagnetization direction is placed upon the small circle of each site. (iii) The acquisition of the remagnetization was simultaneous for the analyzed rocks. Therefore, the remagnetization direction must to be placed upon the small circle for all sites and hence the all small circle must to intersect in one direction which corresponds with the remagnetization direction. Actually the method looks for the direction in the space closest to the set of SCs by means of A/n parameter (this is the sum of the angular distances between one direction and each SC normalized by the number of sites). Once the remagnetization direction is known, it is possible to calculate the paleomagnetic direction upon each SC closest to the calculated remagnetization direction, called as Best Fit Direction (BFD). After that the paleodip of the bed (i.e. the dip of the bed at the moment of the remagnetization event) can be calculated for each site (the paleodip is the angle measured over the SC between the BFD and the paleomagnetic direction after the complete bedding correction) and perform a palinspastic reconstruction of a region. We present pySCIs, a new python tool which allows applying this methodology in an easy way. The program has two different modules, pySCIs_calc.py and pySCIs_draw.py. The first one performs all calculations whereas the second one provides a graphical output. The input data are a comma delimited text file with the name of the sites, the in situ paleomagnetic directions and the attitude beds. After perform the calculations, pySCIs_calc.py export four text files: (i) one of them with all information regarding the paleomagnetic direction and the paleodip, (i) other with the calculated remagnetization direction, (iii) a third one with the direction of the intersections between the small circles and (iv) the last one with a one degree grid with the values of A/n. The graphical output consist in four equal area projections, three of them with the SCs and the paleomagnetic direction in different stages (before and after the bedding correction and the BFD) and the last one is a contour plot of A/n and the intersection between the SCs.

  9. Merging Geospatial Data into a User-Friendly Application to Support Sustainable Development Project

    Data.gov (United States)

    National Aeronautics and Space Administration — An economic development tool, for use at SSC, was developed to generate portfolios coupling standard descriptors about potential sites with maps and location...

  10. Early Intervention Evaluation Reports: Guidelines for Writing User-Friendly and Strength-Based Assessments

    Science.gov (United States)

    Towle, Patricia; Farrell, Anne F.; Vitalone-Raccaro, Nancy

    2008-01-01

    Assessment and evaluation activities are an integral part of early intervention services. These activities culminate in written evaluation reports that include information such as observations of skills and deficits, diagnosis, and recommendations for intervention. However, few guidelines exist to help guide early intervention providers in writing…

  11. Quantitative lateral flow strip assays as user-friendly tools to detect biomarker profiles for leprosy

    NARCIS (Netherlands)

    Van Hooij, A. (Anouk); Tjon Kon Fat, E.M. (Elisa M.); R. Richardus (Renate); S.J.F. van den Eeden (Susan); L. Wilson (Lindsay); De Dood, C.J. (Claudia J.); R. Faber (Roel); Alam, K. (Korshed); J.H. Richardus (Jan Hendrik); Corstjens, P.L.A.M. (Paul L. A. M.); A. Geluk (Annemieke)

    2016-01-01

    textabstractLeprosy is a debilitating, infectious disease caused by Mycobacterium leprae. Despite the availability of multidrug therapy, transmission is unremitting. Thus, early identification of M. leprae infection is essential to reduce transmission. The immune response to M. leprae is determined

  12. Reproducible analysis of sequencing-based RNA structure probing data with user-friendly tools

    DEFF Research Database (Denmark)

    Kielpinski, Lukasz Jan; Sidiropoulos, Nikos; Vinther, Jeppe

    2015-01-01

    coordinates and vice versa. The collection is implemented as functions in the R statistical environment and as tools in the Galaxy platform, making them easily accessible for the scientific community. We demonstrate the usefulness of the collection by applying it to the analysis of sequencing-based hydroxyl......, we have made a collection of tools, which allow raw sequencing reads to be converted to normalized probing values using different published strategies. In addition, we also provide tools for visualization of the probing data in the UCSC Genome Browser and for converting RNA coordinates to genomic...

  13. StochPy: A Comprehensive, User-Friendly Tool for Simulating Stochastic Biological Processes

    NARCIS (Netherlands)

    Maarleveld, T.R.; Olivier, B.G.; Bruggeman, F.J.

    2013-01-01

    Single-cell and single-molecule measurements indicate the importance of stochastic phenomena in cell biology. Stochasticity creates spontaneous differences in the copy numbers of key macromolecules and the timing of reaction events between genetically-identical cells. Mathematical models are indispe

  14. A user-friendly database of coastal flooding in the United Kingdom from 1915–2014

    OpenAIRE

    Haigh, Ivan D.; Wadey, Matthew P.; Gallop, Shari L.; Loehr, Heiko; Nicholls, Robert J.; Horsburgh, Kevin; Jennifer M Brown; Bradshaw, Elizabeth

    2015-01-01

    Coastal flooding caused by extreme sea levels can be devastating, with long-lasting and diverse consequences. Historically, the UK has suffered major flooding events, and at present 2.5 million properties and £150 billion of assets are potentially exposed to coastal flooding. However, no formal system is in place to catalogue which storms and high sea level events progress to coastal flooding. Furthermore, information on the extent of flooding and associated damages is not systematically docu...

  15. WebCT: Will the Future of Online Education be User-friendly?

    Directory of Open Access Journals (Sweden)

    Tama Leaver

    2003-01-01

    Full Text Available In 2004, the Faculty of Arts, Humanities and Social Sciences at the University of Western Australia will cease using The Forum, an in-house developed online education delivery system, and will shift to the popular corporate American online courseware package, or Managed Learning Environment, WebCT (Web Course Tools. The process of migrating to a new online education environment is an ideal moment to ask some important questions about WebCT and the implications this delivery platform holds for online education in a more general sense. I stress that this paper is not intended as an exhaustive critique or how-to guide for WebCT course creation. Rather, this paper narrates the two levels of engagement I have experienced thus far with WebCT. Firstly, I describe my initial reactions to the WebCT suite itself as it is set up at the University of Western Australia. This engagement includes concerns about both the structure of the program, and the underlying architecture of student and teacher interaction. Secondly, I analyse WebCT as a corporate entity and discuss issues raised from a close reading of elements of the WebCT homepage, the marketing strategy, and the directions WebCT as courseware package is heading according to their "white paper" on future developments. In the course of this analysis, I offer a framework to consider whether WebCT is an ideal technological partner in the teaching process, or whether it unavoidably closes avenues of learning.

  16. Compact and user-friendly ultrasound acquisition systems optimized for field recording

    Directory of Open Access Journals (Sweden)

    Specht Raimund

    2004-01-01

    Full Text Available A compact and rugged hardware interface for laptop-based ultrasound recording in the field has been developed. The versatile devices overcome the limitations and drawbacks of previously available solutions. The accompanying recording software enables flexible hard disk recording for both manual and automated operation.

  17. A Design Analysis and Implementation of a User-Friendly Interface for the UNIX Operating System.

    Science.gov (United States)

    1984-06-01

    cr.e icrd or short ;hrase of x.lanaticn for the =,-,and. e.,:. -JW Delete n worls . Two fa toar s af fe:t Ing the des i.-r rust te ccnsidered: space and...is sient epttin,. simrle menus, and tr.eir associated selecti n moiiules on the screen and runnint. A program or #rahi:s editor shoula be atle tc

  18. Baryscan: a sensitive and user-friendly alternative to Z scan for weak nonlinearities measurements.

    Science.gov (United States)

    Godin, Thomas; Fromager, Michael; Cagniot, Emmanuel; Moncorgé, Richard; Aït-Ameur, Kamel

    2011-04-15

    A new and efficient technique for measuring weak optical nonlinearities is reported. Like Z scan, its implementation is basic, both experimentally and theoretically, but leads to an improved sensitivity of λ/5.10⁴, which represents, to date, one of the highest observed enhancements. With this technique, which is based upon the use of a position sensitive detector, nonlinear properties are deduced by monitoring the barycentric position of a truncated pump-probe laser beam as the sample is moved along the optical axis. The technique is experimentally validated by measuring the pump-induced refractive index change and the underlying polarizability variation resulting from the excitation of the Cr(3+) ions in ruby.

  19. Algorithmic complexity for psychology: a user-friendly implementation of the coding theorem method.

    Science.gov (United States)

    Gauvrit, Nicolas; Singmann, Henrik; Soler-Toscano, Fernando; Zenil, Hector

    2016-03-01

    Kolmogorov-Chaitin complexity has long been believed to be impossible to approximate when it comes to short sequences (e.g. of length 5-50). However, with the newly developed coding theorem method the complexity of strings of length 2-11 can now be numerically estimated. We present the theoretical basis of algorithmic complexity for short strings (ACSS) and describe an R-package providing functions based on ACSS that will cover psychologists' needs and improve upon previous methods in three ways: (1) ACSS is now available not only for binary strings, but for strings based on up to 9 different symbols, (2) ACSS no longer requires time-consuming computing, and (3) a new approach based on ACSS gives access to an estimation of the complexity of strings of any length. Finally, three illustrative examples show how these tools can be applied to psychology.

  20. Short and user-friendly: The development and validation of the Mini-DBQ

    DEFF Research Database (Denmark)

    Martinussen, Laila Marianne; Lajunen, Timo; Møller, Mette

    2013-01-01

    The Driver Behavior Questionnaire (DBQ) is used to measure aberrant driver behavior by asking drivers how often they engage in various aberrant driver behaviors. Since the development of the original DBQ, several modified versions have been developed. The difference between the various versions...... by reducing the 27-item original DBQ to the shortest possible DBQ version. A second aim was to explore the feasibility of a second-order structure within the data, which means that violations, errors and lapses factors load on a higher-order aberrant driver behavior factor. The presence of a second...... for the DBQ. The results indicated a nine-item Mini-DBQ. In addition, a second-order structure was established in the data. These findings indicate that the Mini-DBQ is a valid and useful short measure of aberrant driver behavior....

  1. Short and user-friendly: the development and validation of the Mini-DBQ

    DEFF Research Database (Denmark)

    Martinussen, Laila Marianne; Lajunen, Timo; Møller, Mette

    The Driver Behavior Questionnaire (DBQ) is used to measure aberrant driver behavior by asking drivers how often they engage in various aberrant driver behaviors. Since the development of the original DBQ, several modified versions have been developed. The difference between the various versions...... by reducing the 27-item original DBQ to the shortest possible DBQ version. A second aim was to explore the feasibility of a second-order structure within the data, which means that violations, errors and lapses factors load on a higher-order aberrant driver behavior factor. The presence of a second...... for the DBQ. The results identified a nine-item Mini-DBQ. In addition, a second-order structure was established in the data. These findings indicate that the Mini-DBQ is a valid and useful short measure of aberrant driver behavior....

  2. Global Least-cost User-friendly CLEWs Open-Source Exploratory (GLUCOSE) Model

    Science.gov (United States)

    Taliotis, Constantinos; Roehrl, Richard Alexander; Howells, Mark

    2016-04-01

    A changing climate will force us to consider broad resource management questions. Land, energy and water are some of our most precious resources. The systems that provide them are highly interlinked, vulnerable and contribute to climate change. The UN recognizes the need for integrated assessment of the food-water-energy nexus in international negotiations; highlighted by the inclusion of the Climate, Land-use, Energy and Water (CLEW) nexus in the upcoming Global Sustainable Development Report. This effort provides a toolkit to assist in the formulation of climate change mitigation and adaptation strategies. Building on initial CLEW assessments, we propose the formulation of a fully integrated CLEW modelling tool to enable resource assessments, a global CLEW model, and focusing on scenarios with particular relevance to the climate change and sustainable development discourse. The aim of the overall effort is to create a transparent tool to act as a simplified testing ground for policies and allow the visualisation and assessment of different policy pathways in regards to sustainable development on a global scale. This tool will allow for the identification of potential trade-offs and synergies between sectors in CLEWs and material industry. It should be highlighted that we refrain from implying that this model will be characterized by a high predictive capacity; on the contrary, its main purpose is to provide an initial set of communicable insights and indications to facilitate decision-making on potential plans and strategies.

  3. Three Applications of Automated Test Assembly within a User-Friendly Modeling Environment

    Directory of Open Access Journals (Sweden)

    Ken Cor

    2009-06-01

    Full Text Available While linear programming is a common tool in business and industry, there have not been many applications in educational assessment and only a handful of individuals have been actively involved in conducting psychometric research in this area. Perhaps this is due, at least in part, to the complexity of existing software packages. This article presents three applications of linear programming to automate test assembly using an add-in to Microsoft Excel 2007. These increasingly complex examples permit the reader to readily see and manipulate the programming objectives and constraints within a familiar modeling environment. A spreadsheet used in this demonstration is available for downloading.

  4. Lattice and momentum space approach to bound states and excitonic condensation via user friendly interfaces

    Science.gov (United States)

    Jamell, Christopher Ray

    In this thesis, we focus on two broad categories of problems, exciton condensation and bound states, and two complimentary approaches, real and momentum space, to solve these problems. In chapter 2 we begin by developing the self-consistent mean field equations, in momentum space, used to calculate exciton condensation in semiconductor heterostructures/double quantum wells and graphene. In the double quantum well case, where we have one layer containing electrons and the other layer with holes separated by a distance d, we extend the analytical solution to the two dimensional hydrogen atom in order to provide a semi-quantitative measure of when a system of excitons can be considered dilute. Next we focus on the problem of electron-electron screening, using the random phase approximation, in double layer graphene. The literature contains calculations showing that when screening is not taken into account the temperature at which excitons in double layer graphene condense is approximately room temperature. Also in the literature is a calculation showing that under certain assumptions the transition temperature is approximately mK. The essential result is that the condensate is exponentially suppressed by the number of electron species in the system. Our mean field calculations show that the condensate, is in fact, not exponentially suppressed. Next, in chapter 3, we show the use of momentum space to solve the Schrodinger equation for a class of potentials that are not usually a part of a quantum mechanics courses. Our approach avoids the typical pitfalls that exist when one tries to discretize the real space Schrodinger equation. This technique widens the number of problems that can presented in an introductory quantum mechanics course while at the same time, because of the ease of its implementation, provides a simple introduction to numerical techniques and programming in general to students. We have furthered this idea by creating a modular program that allows students to choose the potential they wish to solve for while abstracting away the details of how the solution is found. In chapter 4 we revisit the single exciton and exciton condensation in double layer graphene problems through the use of real space lattice models. In the first section, we once again develop the equations needed to solve the problem of exciton condensation in a double layer graphene system. In addition to this we show that by using this technique, we find that for a non-interacting system with a finite non-zero tunneling between the layers that the on-site exciton density is proportional to the tunneling amplitude. The second section returns to the single exciton problem. In agreement with our momentum space calculations, we find that as the layer separation distance is increased the bound state wave function broadens. Finally, an interesting consequence of the lattice model is explored briefly. We show that for a system containing an electron in a periodic potential, there exists a bound state for both an attractive as well as repulsive potential. The bound state for the repulsive potential has as its energy -E0 where E0 is the ground state energy of the attractive potential with the same strength.

  5. DCHAIN: A user-friendly computer program for radioactive decay and reaction chain calculations

    Energy Technology Data Exchange (ETDEWEB)

    East, L.V.

    1994-05-01

    A computer program for calculating the time-dependent daughter populations in radioactive decay and nuclear reaction chains is described. Chain members can have non-zero initial populations and be produced from the preceding chain member as the result of radioactive decay, a nuclear reaction, or both. As presently implemented, chains can contain up to 15 members. Program input can be supplied interactively or read from ASCII data files. Time units for half-lives, etc. can be specified during data entry. Input values are verified and can be modified if necessary, before used in calculations. Output results can be saved in ASCII files in a format suitable for including in reports or other documents. The calculational method, described in some detail, utilizes a generalized form of the Bateman equations. The program is written in the C language in conformance with current ANSI standards and can be used on multiple hardware platforms.

  6. A user-friendly web portal for analyzing conformational changes in structures of Mycobacterium tuberculosis.

    Science.gov (United States)

    Hassan, Sameer; Thangam, Manonanthini; Vasudevan, Praveen; Kumar, G Ramesh; Unni, Rahul; Devi, P K Gayathri; Hanna, Luke Elizabeth

    2015-10-01

    Initiation of the Tuberculosis Structural Consortium has resulted in the expansion of the Mycobacterium tuberculosis (MTB) protein structural database. Currently, 969 experimentally solved structures are available for 354 MTB proteins. This includes multiple crystal structures for a given protein under different functional conditions, such as the presence of different ligands or mutations. In depth analysis of the multiple structures reveal that subtle differences exist in conformations of a given protein under varied conditions. Therefore, it is immensely important to understand the conformational differences between the multiple structures of a given protein in order to select the most suitable structure for molecular docking and structure-based drug designing. Here, we introduce a web portal ( http://bmi.icmr.org.in/mtbsd/torsion.php ) that we developed to provide comparative data on the ensemble of available structures of MTB proteins, such as Cα root means square deviation (RMSD), sequence identity, presence of mutations and torsion angles. Additionally, torsion angles were used to perform principal component analysis (PCA) to identify the conformational differences between the structures. Additionally, we present a few case studies to demonstrate this database. Graphical Abstract Conformational changes seen in the structures of the enoyl-ACP reductase protein encoded by the Mycobacterial gene inhA.

  7. User-Friendly Communication Skills in the Teaching and Learning of Business English.

    Science.gov (United States)

    de Beaugrande, Robert

    2000-01-01

    Reports on a pilot project in teaching and learning business English at the University of Botswana, where English is the language of instruction and, for most learners, a second language. The project was tailored to the prevailing social and academic context as described from the standpoint of discourse analysis. (Author/VWL)

  8. QualitySNPng: a user-friendly SNP detection and visualization tool

    NARCIS (Netherlands)

    Nijveen, H.; Kaauwen, van M.P.W.; Esselink, G.; Hoegen, B.; Vosman, B.

    2013-01-01

    QualitySNPng is a new software tool for the detection and interactive visualization of single-nucleotide polymorphisms (SNPs). It uses a haplotype-based strategy to identify reliable SNPs; it is optimized for the analysis of current RNA-seq data; but it can also be used on genomic DNA sequences deri

  9. A 'User-Friendly' Approach to the Dynamical Equations of Non-Holonomic Systems

    Directory of Open Access Journals (Sweden)

    Sergio Benenti

    2007-03-01

    Full Text Available Two effective methods for writing the dynamical equations for non-holonomic systems are illustrated. They are based on the two types of representation of the constraints: by parametric equations or by implicit equations. They can be applied to linear as well as to non-linear constraints. Only the basic notions of vector calculus on Euclidean 3-space and on tangent bundles are needed. Elementary examples are illustrated.

  10. Cluster Flow: A user-friendly bioinformatics workflow tool [version 1; referees: 3 approved

    Directory of Open Access Journals (Sweden)

    Philip Ewels

    2016-12-01

    Full Text Available Pipeline tools are becoming increasingly important within the field of bioinformatics. Using a pipeline manager to manage and run workflows comprised of multiple tools reduces workload and makes analysis results more reproducible. Existing tools require significant work to install and get running, typically needing pipeline scripts to be written from scratch before running any analysis. We present Cluster Flow, a simple and flexible bioinformatics pipeline tool designed to be quick and easy to install. Cluster Flow comes with 40 modules for common NGS processing steps, ready to work out of the box. Pipelines are assembled using these modules with a simple syntax that can be easily modified as required. Core helper functions automate many common NGS procedures, making running pipelines simple. Cluster Flow is available with an GNU GPLv3 license on GitHub. Documentation, examples and an online demo are available at http://clusterflow.io.

  11. PIVlab – Towards User-friendly, Affordable and Accurate Digital Particle Image Velocimetry in MATLAB

    NARCIS (Netherlands)

    Stamhuis, Eize; Thielicke, William

    2014-01-01

    Digital particle image velocimetry (DPIV) is a non-intrusive analysis technique that is very popular for mapping flows quantitatively. To get accurate results, in particular in complex flow fields, a number of challenges have to be faced and solved: The quality of the flow measurements is affected b

  12. PIVlab – Towards User-friendly, Affordable and Accurate Digital Particle Image Velocimetry in MATLAB

    NARCIS (Netherlands)

    Stamhuis, Eize; Thielicke, William

    2014-01-01

    Digital particle image velocimetry (DPIV) is a non-intrusive analysis technique that is very popular for mapping flows quantitatively. To get accurate results, in particular in complex flow fields, a number of challenges have to be faced and solved: The quality of the flow measurements is affected

  13. A user-friendly approach to cost accounting in laboratory animal facilities.

    Science.gov (United States)

    Baker, David G

    2011-08-19

    Cost accounting is an essential management activity for laboratory animal facility management. In this report, the author describes basic principles of cost accounting and outlines steps for carrying out cost accounting in laboratory animal facilities. Methods of post hoc cost accounting analysis for maximizing the efficiency of facility operations are also described.

  14. DNAseq Workflow in a Diagnostic Context and an Example of a User Friendly Implementation

    Directory of Open Access Journals (Sweden)

    Beat Wolf

    2015-01-01

    Full Text Available Over recent years next generation sequencing (NGS technologies evolved from costly tools used by very few, to a much more accessible and economically viable technology. Through this recently gained popularity, its use-cases expanded from research environments into clinical settings. But the technical know-how and infrastructure required to analyze the data remain an obstacle for a wider adoption of this technology, especially in smaller laboratories. We present GensearchNGS, a commercial DNAseq software suite distributed by Phenosystems SA. The focus of GensearchNGS is the optimal usage of already existing infrastructure, while keeping its use simple. This is achieved through the integration of existing tools in a comprehensive software environment, as well as custom algorithms developed with the restrictions of limited infrastructures in mind. This includes the possibility to connect multiple computers to speed up computing intensive parts of the analysis such as sequence alignments. We present a typical DNAseq workflow for NGS data analysis and the approach GensearchNGS takes to implement it. The presented workflow goes from raw data quality control to the final variant report. This includes features such as gene panels and the integration of online databases, like Ensembl for annotations or Cafe Variome for variant sharing.

  15. In-vehicle human factors for integrated multi-function systems: Making ITS user-friendly

    Energy Technology Data Exchange (ETDEWEB)

    Spelt, P.F.; Scott, S.

    1998-04-01

    As more and more Intelligent Transportation System in-vehicle equipment enters the general consumer market, the authors are about to find out how different design engineers are from ordinary drivers. Driver information systems are being developed and installed in vehicles at an ever-increasing rate. These systems provide information on diverse topics of concern and convenience to the driver, such as routing and navigation, emergency and collision warnings, and a variety of motorists services, or yellow pages functions. Most of these systems are being developed and installed in isolation from each other, with separate means of gathering the information and of displaying it to the driver. The current lack of coordination among on-board systems threatens to create a situation in which different messages on separate displays will be competing with each other for the drivers attention. Urgent messages may go unnoticed, and the number of messages may distract the driver from the most critical task of controlling the vehicle. Thus, without good human factors design and engineering for integrating multiple systems in the vehicle, consumers may find ITS systems confusing and frustrating to use. The current state of the art in human factors research and design for in-vehicle systems has a number of fundamental gaps. Some of these gaps were identified during the Intelligent Vehicle Initiative Human Factors Technology Workshop, sponsored by the US Department of Transportation, in Troy, Michigan, December 10--11, 1997. One task for workshop participants was to identify needed research areas or topics relating to in-vehicle human factors. The top ten unmet research needs from this workshop are presented. Many of these gaps in human factors research knowledge indicate the need for standardization in the functioning of interfaces for safety-related devices such as collision avoidance systems (CAS) and adaptive cruise controls (ACC). Such standards and guidelines will serve to make the safety-critical aspects of these systems consistent across different manufacturers, thereby reducing the likelihood of driver surprise. A second area to emerge from the Workshop concerns research into techniques for integrating multiple devices in vehicles. This type of research is needed to support the development and validation of standards and guidelines, and is discussed in the second section. The majority of the top ten research types identified in the Workshop fall under the need for a Science of Driving, which is discussed in the last section of this paper.

  16. Development of User-Friendly Software to Design Dairy Heat Exchanger and Performance Evaluation

    Directory of Open Access Journals (Sweden)

    DipankarMandal

    2015-02-01

    Full Text Available The paper proposes a calculation algorithm and development of a software in Visual Basic(Visual Studio 2012 Express Desktop used in heat transfer studies when different heat exchangers are involved (e.g. Helical Type Triple Tube Heat Exchanger , Plate Type Heat Exchanger.It includes the easy calculation of heat transfer coefficient and followed by the design and simulation of heat exchanger design parameter by inputting general known parameters of a heat exchanger into the developed software—-―DAIRY –HE ―. A parametric study is conducted using the software interface to determine the length of tubes or dimensions of heat exchanger.

  17. DivStat: a user-friendly tool for single nucleotide polymorphism analysis of genomic diversity.

    Directory of Open Access Journals (Sweden)

    Inês Soares

    Full Text Available Recent developments have led to an enormous increase of publicly available large genomic data, including complete genomes. The 1000 Genomes Project was a major contributor, releasing the results of sequencing a large number of individual genomes, and allowing for a myriad of large scale studies on human genetic variation. However, the tools currently available are insufficient when the goal concerns some analyses of data sets encompassing more than hundreds of base pairs and when considering haplotype sequences of single nucleotide polymorphisms (SNPs. Here, we present a new and potent tool to deal with large data sets allowing the computation of a variety of summary statistics of population genetic data, increasing the speed of data analysis.

  18. IllinoisGRMHD: an open-source, user-friendly GRMHD code for dynamical spacetimes

    Science.gov (United States)

    Etienne, Zachariah B.; Paschalidis, Vasileios; Haas, Roland; Mösta, Philipp; Shapiro, Stuart L.

    2015-09-01

    In the extreme violence of merger and mass accretion, compact objects like black holes and neutron stars are thought to launch some of the most luminous outbursts of electromagnetic and gravitational wave energy in the Universe. Modeling these systems realistically is a central problem in theoretical astrophysics, but has proven extremely challenging, requiring the development of numerical relativity codes that solve Einstein's equations for the spacetime, coupled to the equations of general relativistic (ideal) magnetohydrodynamics (GRMHD) for the magnetized fluids. Over the past decade, the Illinois numerical relativity (ILNR) group's dynamical spacetime GRMHD code has proven itself as a robust and reliable tool for theoretical modeling of such GRMHD phenomena. However, the code was written ‘by experts and for experts’ of the code, with a steep learning curve that would severely hinder community adoption if it were open-sourced. Here we present IllinoisGRMHD, which is an open-source, highly extensible rewrite of the original closed-source GRMHD code of the ILNR group. Reducing the learning curve was the primary focus of this rewrite, with the goal of facilitating community involvement in the code's use and development, as well as the minimization of human effort in generating new science. IllinoisGRMHD also saves computer time, generating roundoff-precision identical output to the original code on adaptive-mesh grids, but nearly twice as fast at scales of hundreds to thousands of cores.

  19. IllinoisGRMHD: An Open-Source, User-Friendly GRMHD Code for Dynamical Spacetimes

    CERN Document Server

    Etienne, Zachariah B; Haas, Roland; Moesta, Philipp; Shapiro, Stuart L

    2015-01-01

    In the extreme violence of merger and mass accretion, compact objects like black holes and neutron stars are thought to launch some of the most luminous outbursts of electromagnetic and gravitational wave energy in the Universe. Modeling these systems realistically is a central problem in theoretical astrophysics, but has proven extremely challenging, requiring the development of numerical relativity codes that solve Einstein's equations for the spacetime, coupled to the equations of general relativistic (ideal) magnetohydrodynamics (GRMHD) for the magnetized fluids. Over the past decade, the Illinois Numerical Relativity (ILNR) Group's dynamical spacetime, GRMHD code has proven itself as one of the most robust and reliable tools for theoretical modeling of such GRMHD phenomena. Despite the code's outstanding reputation, it was written "by experts and for experts" of the code, with a steep learning curve that would severely hinder community adoption if it were open-sourced. Here we present IllinoisGRMHD, whic...

  20. A study of user authentication using mobile phone

    OpenAIRE

    Hallsteinsen, Steffen Gullikstad

    2007-01-01

    The number of different identities and credentials used for authentication towards services on the Internet has increased beyond the manageable. Still, the most common authentication scheme is based on usernames and passwords which are neither secure nor user-friendly. Hence, better solutions for simplified, yet secure authentication, is required in the future. This thesis present an authentication scheme based on a One-Time Password (OTP) MIDlet running on a mobile phone for unified authenti...