WorldWideScience

Sample records for range reported previously

  1. Substring Range Reporting

    DEFF Research Database (Denmark)

    Bille, Philip; Gørtz, Inge Li

    2014-01-01

    We revisit various string indexing problems with range reporting features, namely, position-restricted substring searching, indexing substrings with gaps, and indexing substrings with intervals. We obtain the following main results. We give efficient reductions for each of the above problems...... to a new problem, which we call substring range reporting. Hence, we unify the previous work by showing that we may restrict our attention to a single problem rather than studying each of the above problems individually. We show how to solve substring range reporting with optimal query time and little...... for substring range reporting generalize to substring range counting and substring range emptiness variants. We also obtain non-trivial time-space trade-offs for these problems. Our bounds for substring range reporting are based on a novel combination of suffix trees and range reporting data structures...

  2. Substring Range Reporting

    DEFF Research Database (Denmark)

    Bille, Philip; Gørtz, Inge Li

    2011-01-01

    We revisit various string indexing problems with range reporting features, namely, position-restricted substring searching, indexing substrings with gaps, and indexing substrings with intervals. We obtain the following main results. – We give efficient reductions for each of the above problems...... to a new problem, which we call substring range reporting. Hence, we unify the previous work by showing that we may restrict our attention to a single problem rather than studying each of the above problems individually. – We show how to solve substring range reporting with optimal query time and little...... range reporting are based on a novel combination of suffix trees and range reporting data structures. The reductions are simple and general and may apply to other combinations of string indexing with range reporting....

  3. Online Sorted Range Reporting

    DEFF Research Database (Denmark)

    Brodal, Gerth Stølting; Fagerberg, Rolf; Greve, Mark

    2009-01-01

    We study the following one-dimensional range reporting problem: On an arrayA of n elements, support queries that given two indices i ≤ j and an integerk report the k smallest elements in the subarray A[i..j] in sorted order. We present a data structure in the RAM model supporting such queries...... in optimal O(k) time. The structure uses O(n) words of space and can be constructed in O(n logn) time. The data structure can be extended to solve the online version of the problem, where the elements in A[i..j] are reported one-by-one in sorted order, in O(1) worst-case time per element. The problem...... is motivated by (and is a generalization of) a problem with applications in search engines: On a tree where leaves have associated rank values, report the highest ranked leaves in a given subtree. Finally, the problem studied generalizes the classic range minimum query (RMQ) problem on arrays....

  4. Steller sea lion sightings or recaptures of previously marked animals throughout their range, 1987-2014

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset contains information regarding the sighting and capture of previously marked Steller sea lions from 1987 to the present. Marks are seen and documented...

  5. Kenai National Moose Range : Narrative report : 1968

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This annual narrative report for Kenai National Moose Range outlines Refuge accomplishments during the 1968 calendar year. The report begins by summarizing the...

  6. Report to Congress on Sustainable Ranges

    Science.gov (United States)

    2007-07-01

    Laysan Albatrosses , and the recovery of a shoreline/littoral zone when human traffic is limited to security vehicles and personnel. This range...Requirements Module (ARRM) and feed the Installation Status C-8 July 2007 2007 SUSTAINABLE RANGES REPORT Report-Natural Infrastructure (see

  7. 2008 NASA Range Safety Annual Report

    Science.gov (United States)

    Lamoreaux, Richard W.

    2008-01-01

    Welcome to the 2008 edition of the NASA Range Safety Annual Report. Funded by NASA Headquarters, this report provides a NASA Range Safety overview for current and potential range users. This year, along with full length articles concerning various subject areas, we have provided updates to standard subjects with links back to the 2007 original article. Additionally, we present summaries from the various NASA Range Safety Program activities that took place throughout the year, as well as information on several special projects that may have a profound impact on the way we will do business in the future. The sections include a program overview and 2008 highlights of Range Safety Training; Range Safety Policy; Independent Assessments and Common Risk Analysis Tools Development; Support to Program Operations at all ranges conducting NASA launch operations; a continuing overview of emerging Range Safety-related technologies; Special Interests Items that include recent changes in the ELV Payload Safety Program and the VAS explosive siting study; and status reports from all of the NASA Centers that have Range Safety responsibilities. As is the case each year, contributors to this report are too numerous to mention, but we thank individuals from the NASA Centers, the Department of Defense, and civilian organizations for their contributions. We have made a great effort to include the most current information available. We recommend that this report be used only for guidance and that the validity and accuracy of all articles be verified for updates. This is the third year we have utilized this web-based format for the annual report. We continually receive positive feedback on the web-based edition, and we hope you enjoy this year's product as well. It has been a very busy and productive year on many fronts as you will note as you review this report. Thank you to everyone who contributed to make this year a successful one, and I look forward to working with all of you in the

  8. Optimal Static Range Reporting in One Dimension

    DEFF Research Database (Denmark)

    Alstrup, Stephen; Brodal, Gerth Stølting; Rauhe, Theis

    2001-01-01

    a query interval, we present an optimal data structure with linear space cost and with query time linear in the number of integers reported. This result holds in the unit cost RAM model with word size w and a standard instruction set. We also present a linear space data structure for approximate range...

  9. Report to Congress on Sustainable Ranges, 2011

    Science.gov (United States)

    2011-07-01

    Services (IGI&S) data proponency, Common Installation Picture, and Quality Assurance Plans ( QAPs ). Based on this guidance, all Army installations are...Sustainable Ranges Report July 2011 Support Center are defined in each layer’s geospatial data QAP . QAPs provide the definition, information about the...requirements for each of the data layers. QAPs are living documents and are maintained by the HQDA proponent with input from the installation data

  10. Report to Congress on Sustainable Ranges, 2008

    Science.gov (United States)

    2008-01-01

    Air Facility Quantico in FY2008. RAICUZ studies at Townsend Range, Chocolate Mountain Aerial Gunnery Range, and Barry M Goldwater Range-West are on...representatives from Arizona, California, Nevada, New Mexico and Utah and other interested stakeholders. Part of the working group’s tactical

  11. Report to Congress on Sustainable Ranges, 2010

    Science.gov (United States)

    2010-05-01

    Continuing to work with JIOR to provide a mobile service which can be deployed at the Urban Operations Complex ( UOC ) on Range 62. Electronic Combat...range; some means of facilitating IO play but no organic capability. NTTR continuing to work with JIOR to provide a mobile service to deploy at UOC ...no organic capability. Continuing to work with JIOR to provide a mobile service which can be deployed at the UOC . Collective Ranges Information

  12. Report to Congress on Sustainable Ranges, 2015

    Science.gov (United States)

    2015-03-01

    no organic capability. HQ NTTR continues to work with JIOR to provide a mobile service which can be deployed at the Urban Operations Complex ( UOC ...NTTR continues to work with JIOR to provide a mobile service which can be deployed at the Urban Operations Complex ( UOC ) on Range 62. Electronic... UOC ) on Range 62. Electronic Combat Support h The range lacks a complete electronic target set. EA platforms do not get real-time feedback on their

  13. Groin Problems in Male Soccer Players Are More Common Than Previously Reported.

    Science.gov (United States)

    Harøy, Joar; Clarsen, Ben; Thorborg, Kristian; Hölmich, Per; Bahr, Roald; Andersen, Thor Einar

    2017-05-01

    The majority of surveillance studies in soccer have used a time-loss injury definition, and many groin problems result from overuse, leading to gradually increasing pain and/or reduced performance without necessarily causing an absence from soccer training or match play. Thus, the magnitude of groin problems in soccer has probably been underestimated in previous studies based on traditional injury surveillance methods. To investigate the prevalence of groin problems among soccer players of both sexes and among male soccer players at different levels of play through a new surveillance method developed to capture acute and overuse problems. Descriptive epidemiology study. We registered groin problems during a 6-week period of match congestion using the Oslo Sports Trauma Research Center Overuse Injury Questionnaire. A total of 240 players from 15 teams across different levels of play and from both sexes were included, and they responded to the weekly questionnaire. We calculated the average weekly prevalence of all groin problems and substantial groin problems. Of the 240 players, 112 male players (59%) and 20 female players (45%) reported at least 1 episode of groin problems. The average weekly prevalence of any groin problem and substantial groin problem for all male players was 29% (range, 23%-32% across different levels) and 10% (7%-13%), respectively. Elite male players had an increased risk of experiencing groin problems (odds ratio: 3.1, 95% CI: 1.5-6.4, P = .03) compared with elite female players. There was no difference in the risk of experiencing groin problems among elite, subelite, and amateur male players. For substantial problems, there was no difference between elite male and elite female players or among levels of play for senior male soccer players. We found a high prevalence of groin problems among male soccer players during a period with match congestion. Time-loss definition as used in previous injury surveillance studies captured only one

  14. Arctic National Wildlife Range, Annual Narrative Report

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The Arctic National Wildlife Range (ANWR) was established by executive order in 1960 for the purpose of preserving unique wildlife, wilderness and recreational...

  15. Report to Congress on Sustainable Ranges, 2013

    Science.gov (United States)

    2013-04-01

    research, tsunami warning/verification, and seismic / earthquake monitoring. The littoral nature of Navy training ranges and the unique types of...training. `` Completed Phases 1 (Mountainside Village) and 2 (Hillside Tunnels ) of four-phase urban training complex plan. Ongoing Progress

  16. Report to Congress on Sustainable Ranges

    Science.gov (United States)

    2014-02-01

    research, climate research, tsunami warning/ verification, and seismic /earthquake monitoring. The littoral nature of Navy training ranges and the unique...Mountainside Village) and 2 (Hillside Tunnels ) of four-phase urban training complex plan. Ongoing Progress continuing into 2014. 252014 Sustainable

  17. Ovarian Sex Cord-stromal Tumors With Melanin Pigment: Report of a Previously Undescribed Phenomenon.

    Science.gov (United States)

    Taylor, Jennifer; McCluggage, W Glenn

    2017-11-14

    We report 2 ovarian sex cord-stromal tumors, a luteinized adult granulosa cell tumor and a cellular fibroma, with melanin pigment. These occurred in 44 and 61-yr-old patients, respectively. As far as we are aware, melanin pigment has not been described previously in an ovarian sex cord-stromal tumor, although it has been reported in a testicular Sertoli cell tumor. We review ovarian neoplasms containing melanin pigment.

  18. Logic of Accounting: The Case of Reporting Previous Options in Norwegian Activation Encounters

    Science.gov (United States)

    Solberg, Janne

    2017-01-01

    The article deals with the enactment of client resistance in Norwegian vocational rehabilitation encounters. More specific, a practice here called "reporting previous options" is analyzed by using the resources of ethnomethodological conversation analysis (CA) in five instances as doing some sort of accounting. In response to the…

  19. Cannabinoid hyperemesis syndrome. A report of six new cases and a summary of previous reports.

    Science.gov (United States)

    Contreras Narváez, Carla; Mola Gilbert, Montserrat; Batlle de Santiago, Enric; Bigas Farreres, Jordi; Giné Serven, Eloy; Cañete Crespillo, Josep

    2016-03-02

    Cannabinoid hyperemesis syndrome (CHS) is a medical condition which was identified for the first time in 2004 and affects chronic users of cannabis. It is characterized by cyclic episodes of uncontrollable vomiting as well as compulsive bathing in hot water. The episodes have a duration of two to four days. The vomiting is recognizable by a lack of response to regular antiemetic treatment, and subsides only with cannabis abstinence, reappearing in periods of consumption of this substance. The etiology of this syndrome is unknown. Up until June 2014, 83 cases of CHS were published worldwide, four of them in Spain.The first patient of CHS at Mataró Hospital was diagnosed in 2012. Since then, five new cases have been identified. The average duration between the onset of acute CHS episodes and diagnosis is 6.1 years, similar to that observed in previously published cases, an average of 3.1 years. This "delay" of CHS diagnosis demonstrates a lack of awareness with respect to this medical condition in the healthcare profession.With the objective of providing information concerning CHS and facilitating its timely diagnosis, a series of six new cases of CHS diagnosed in Mataró Hospital is presented along with a summary of cases published between 2004 and June 2014.

  20. Disseminated Infection Caused by Eggerthella lenta in a Previously Healthy Young Man: A Case Report

    Directory of Open Access Journals (Sweden)

    Ahmad Salameh

    2012-01-01

    Full Text Available Anaerobic bacteria are the predominant normal flora of the mucous membranes which may cause life-threatening disseminated infections and are often difficult to culture from infected sites. Eggerthella (previously known as Eubacteria species is an anaerobic, nonsporulating, nonmotile, Gram-positive rod that is found in the human colon and feces and has been isolated from various other clinical specimens. We report a case of complicated disseminated anaerobic bacterial infection with Eggerthella lenta in a healthy immunocompetent man causing multiple brain abscesses, liver abscesses, necrotizing pneumonia, and osteomyelitis of the left radial bone. He was successfully treated with empiric penicillin G and metronidazole.

  1. Eikenella corrodens endocarditis and liver abscess in a previously healthy male, a case report

    DEFF Research Database (Denmark)

    Nordholm, Anne Christine; Vøgg, Ruth Ottilia Birgitta; Permin, Henrik

    2018-01-01

    BACKGROUND: Eikenella corrodens is one of the HACEK bacteria constituting part of the normal flora of the oropharynx, however, still an uncommon pathogen. We report a case of a large Eikenella corrodens liver abscess with simultaneously endocarditis in a previously healthy male. CASE PRESENTATION...... on pneumonia treatment, a PET-CT scan was performed, which showed a large multiloculated abscess in the liver. The abscess was drained using ultrasound guidance. Culture demonstrated Eikenella corrodens. Transesophageal echocardiography revealed aortic endocarditis. The patient was treated with antibiotics...... corrodens concurrent liver abscess and endocarditis. The case report highlights that Eikenella corrodens should be considered as a cause of liver abscess. Empirical treatment of pyogenic liver abscess will most often cover Eikenella corrodens, but the recommended treatment is a third generation...

  2. Refuge narrative report : 1967 : Kenai National Moose Range

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This annual narrative report for Kenai National Moose Range outlines Refuge accomplishments during the 1967 calendar year. The report begins by summarizing the...

  3. Kenai National Moose Range : Annual narrative report : Calendar year 1966

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This annual narrative report for Kenai National Moose Range outlines Refuge accomplishments during the 1966 calendar year. The report begins by summarizing the...

  4. Kenai National Moose Range : Annual narrative report : Calendar year 1965

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This annual narrative report for Kenai National Moose Range outlines Refuge accomplishments during the 1965 calendar year. The report begins by summarizing the...

  5. National Bison Range, Ninepipe and Pablo Refuges: Narrative report - 1970

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This annual narrative report for National Bison Range, Pablo NWR, and Ninepipe NWR outlines Refuge accomplishments during the 1970 calendar year. The report begins...

  6. National Bison Range Annual narrative report: Calendar year 1991

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This annual narrative report for the National Bison Range outlines Refuge accomplishments for the 1991 calendar year. The report begins with an introduction to the...

  7. National Bison Range: Annual narrative report: Calendar year 1993

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This annual narrative report for the National Bison Range outlines Refuge accomplishments for the 1993 calendar year. The report begins with an introduction to the...

  8. National Bison Range Annual narrative report: Calendar year 1984

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This annual narrative report for the National Bison Range outlines Refuge accomplishments for the 1984 calendar year. The report begins with an introduction to the...

  9. National Bison Range : Annual narrative report: Calendar year 1985

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This annual narrative report for the National Bison Range outlines Refuge accomplishments for the 1985 calendar year. The report begins with an introduction to the...

  10. National Bison Range: Annual narrative report: Calendar year 1992

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This annual narrative report for the National Bison Range outlines Refuge accomplishments for the 1992 calendar year. The report begins with an introduction to the...

  11. National Bison Range Annual narrative report: Calendar year 1983

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This annual narrative report for the National Bison Range outlines Refuge accomplishments for the 1983 calendar year. The report begins with an introduction to the...

  12. National Bison Range Annual narrative report: Calendar year 1982

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This annual narrative report for the National Bison Range outlines Refuge accomplishments for the 1982 calendar year. The report begins with an introduction to the...

  13. National Bison Range Annual narrative report: Calendar year 1990

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This annual narrative report for the National Bison Range outlines Refuge accomplishments for the 1990 calendar year. The report begins with an introduction to the...

  14. National Bison Range Annual narrative report: Calendar year 1988

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This annual narrative report for the National Bison Range outlines Refuge accomplishments for the 1988 calendar year. The report begins with an introduction to the...

  15. National Bison Range Annual narrative report: Calendar year: 1978

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This annual narrative report for the National Bison Range outlines Refuge accomplishments for the 1978 calendar year. The report begins with an introduction to the...

  16. National Bison Range: Refuge narrative report: Calendar year 1966

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This annual narrative report for National Bison Range outlines Refuge accomplishments during the 1966 calendar year. The report begins by summarizing the weather...

  17. National Bison Range: Annual narrative report: Calendar year 1977

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This annual narrative report for the National Bison Range outlines Refuge accomplishments for the 1977 calendar year. The report begins with an introduction to the...

  18. The use of buflomedil in reduction mammaplasty for a previously irradiated breast: a case report.

    Science.gov (United States)

    Sterodimas, A; Vargas, A; Radwanski, H N; Pitanguy, I

    2008-03-01

    In recent years, lumpectomy combined with breast irradiation and chemotherapy, as a part of conservation therapy for breast cancer, has well-established results. Little has been published on reduction mammoplasty for breast-irradiated patients. These patients have increased risks of nipple necrosis, wound complications, and delayed healing. Breast reduction techniques that rely on minimum skin undermining combined with the use of buflomedil may prevent major postoperative complications in breast-irradiated patients. Buflomedil was administered intraoperatively and for 14 days after the procedure. The use of buflomedil in reduction mammaplasty for a previously irradiated breast patient has not been heretofore described. The case of a 58-year-old woman who underwent bilateral breast reduction after breast conservation therapy is reported.

  19. Previously undescribed pulpal and periodontal ligament calcifications in systemic sclerosis: a case report.

    Science.gov (United States)

    Jung, Sophie; Minoux, Maryline; Manière, Marie-Cécile; Martin, Thierry; Schmittbuhl, Matthieu

    2013-04-01

    Systemic sclerosis (SSc), a multisystem autoimmune disease characterized by widespread fibrosis, vascular alterations, autoimmunity, and inflammation, has effects on the hard and soft tissues of the orofacial region. The most common oral radiographic features correspond to widening of the periodontal ligament space and to mandibular resorption. In this report, cone-beam computerized tomography (CBCT) confirmed not only the well described periodontal features associated with SSc but also revealed previously undescribed calcifications within the periodontal ligament space of most maxillary teeth. Moreover, CBCT showed pulp calcifications in some incisors and premolars with these calcifications leading to root canal obliterations. Such manifestations (which could be linked to different major pathogenic features of SSc such as calcinosis, vasculopathy, and fibrosis) contribute to the phenotypic spectrum of the disease. Copyright © 2013 Elsevier Inc. All rights reserved.

  20. Tonopah Test Range Post-Closure Inspection Annual Report, Tonopah Test Range, Nevada, Calendar Year 2003

    Energy Technology Data Exchange (ETDEWEB)

    U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office; Bechtel Nevada

    2004-04-01

    This post-closure inspection report provides documentation of the semiannual inspection activities, maintenance and repair activities, and conclusions and recommendations for calendar year 2003 for eight corrective action units located on the Tonopah Test Range, Nevada.

  1. [Double mutant alleles in the EXT1 gene not previously reported in a teenager with hereditary multiple exostoses].

    Science.gov (United States)

    Cammarata-Scalisi, Francisco; Cozar, Mónica; Grinberg, Daniel; Balcells, Susana; Asteggiano, Carla G; Martínez-Domenech, Gustavo; Bracho, Ana; Sánchez, Yanira; Stock, Frances; Delgado-Luengo, Wilmer; Zara-Chirinos, Carmen; Chacín, José Antonio

    2015-04-01

    Hereditary forms of multiple exostoses, now called EXT1/EXT2-CDG within Congenital Disorders of Glycosylation, are the most common benign bone tumors in humans and clinical description consists of the formation of several cartilage-capped bone tumors, usually benign and localized in the juxta-epiphyseal region of long bones, although wide body dissemination in severe cases is not uncommon. Onset of the disease is variable ranging from 2-3 years up to 13-15 years with an estimated incidence ranging from 1/18,000 to 1/50,000 cases in European countries. We present a double mutant alleles in the EXT1 gene not previously reported in a teenager and her family with hereditary multiple exostoses.

  2. Eikenella corrodens endocarditis and liver abscess in a previously healthy male, a case report.

    Science.gov (United States)

    Nordholm, Anne Christine; Vøgg, Ruth Ottilia Birgitta; Permin, Henrik; Katzenstein, Terese

    2018-01-12

    Eikenella corrodens is one of the HACEK bacteria constituting part of the normal flora of the oropharynx, however, still an uncommon pathogen. We report a case of a large Eikenella corrodens liver abscess with simultaneously endocarditis in a previously healthy male. A 49-year-old Danish man was admitted because of one-month malaise, fever, cough and unintentional weight loss. On admission there was elevated white blood cell count and C-reactive protein, as well as affected liver function tests. Initially pneumonia was suspected, but due to lack of improvement on pneumonia treatment, a PET-CT scan was performed, which showed a large multiloculated abscess in the liver. The abscess was drained using ultrasound guidance. Culture demonstrated Eikenella corrodens. Transesophageal echocardiography revealed aortic endocarditis. The patient was treated with antibiotics and abscess drainage, on which he slowly improved. He was discharged after 1.5 months of hospitalisation. On follow-up 2 months later, the patient was asymptomatic with normalized biochemistry and ultrasound showed complete regression of the abscess. This is the first case of documented Eikenella corrodens concurrent liver abscess and endocarditis. The case report highlights that Eikenella corrodens should be considered as a cause of liver abscess. Empirical treatment of pyogenic liver abscess will most often cover Eikenella corrodens, but the recommended treatment is a third generation cephalosporin or a fluoroquinolon. A multiloculated liver abscess may require drainage several times during treatment. The finding of Eikenella corrodens should elicit an echocardiography to diagnose endocarditis even in patients without clinical signs of endocarditis.

  3. Infantile onset spinocerebellar ataxia 2 (SCA2): a clinical report with review of previous cases.

    Science.gov (United States)

    Singh, Ankur; Faruq, Mohammed; Mukerji, Mitali; Dwivedi, Manish Kumar; Pruthi, Sumit; Kapoor, Seema

    2014-01-01

    Autosomal dominant cerebellar ataxia type I is a heterogeneous group of spinocerebellar ataxias with variable neurologic presentations, with age of onset varying from infancy to adulthood. Autosomal dominant cerebellar ataxia type I is composed mainly of 3 prevalent spinocerebellar ataxia types with different pathogenic loci, specifically spinocerebellar ataxia 1 (6p24-p23), spinocerebellar ataxia 2 (12q24.1), and spinocerebellar ataxia 3 (14q32.1). The shared pathogenic mutational event is the expansion of the CAG repeat that results in polyglutamine extended stretches in the encoded proteins. CAG repeat disorders generally show the phenomenon of anticipation, which is more often associated with paternal transmission. In this report, we describe a patient with infantile-onset spinocerebellar ataxia type 2 (~320 CAG repeat) who inherited the disease from his father (47 CAG repeats). We have summarized the clinical, neuroimaging, electroencephalographic (EEG), and molecular data of previous cases and attempt to highlight the most consistent findings. Our intent is to help treating clinicians to suspect this disorder and to offer timely genetic counseling for a currently potentially untreatable disorder.

  4. Adenylosuccinate lyase (ADSL) and infantile autism: Absence of previously reported point mutation

    Energy Technology Data Exchange (ETDEWEB)

    Fon, E.A.; Sarrazin, J.; Rouleau, G.A. [Montreal General Hospital (Canada)] [and others

    1995-12-18

    Autism is a heterogeneous neuropsychiatric syndrome of unknown etiology. There is evidence that a deficiency in the enzyme adenylosuccinate lyase (ADSL), essential for de novo purine biosynthesis, could be involved in the pathogenesis of certain cases. A point mutation in the ADSL gene, resulting in a predicted serine-to-proline substitution and conferring structural instability to the mutant enzyme, has been reported previously in 3 affected siblings. In order to determine the prevalence of the mutation, we PCR-amplified the exon spanning the site of this mutation from the genomic DNA of patients fulfilling DSM-III-R criteria for autistic disorder. None of the 119 patients tested were found to have this mutation. Furthermore, on preliminary screening using single-strand conformation polymorphism (SSCP), no novel mutations were detected in the coding sequence of four ADSL exons, spanning approximately 50% of the cDNA. In light of these findings, it appears that mutations in the ADSL gene represent a distinctly uncommon cause of autism. 12 refs., 2 figs.

  5. Botanical studies in the Arctic National Wildlife Range: Field report

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report is a botanical study in the Arctic National Wildlife Range during 1970. Cooperative studies on flora and fauna were done on selected sites. Sites include...

  6. Improved Space Bounds for Cache-Oblivious Range Reporting

    DEFF Research Database (Denmark)

    Afshani, Peyman; Zeh, Norbert

    2011-01-01

    second main result shows that any cache-oblivious 2-d three-sided range reporting data structure with the optimal query bound has to use Ω(N logε N) space, thereby improving on a recent lower bound for the same problem. Using known transformations, the lower bound extends to 3-d dominance reporting and 3......We provide improved bounds on the size of cacheoblivious range reporting data structures that achieve the optimal query bound of O(logB N + K/B) block transfers. Our first main result is an O(N √ logN log logN)-space data structure that achieves this query bound for 3-d dominance reporting and 2-d...... three-sided range reporting. No cache-oblivious o(N log N/ log logN)-space data structure for these problems was known before, even when allowing a query bound of O(logO(1) 2 N + K/B) block transfers.1 Our result also implies improved space bounds for general 2-d and 3-d orthogonal range reporting. Our...

  7. Near-Optimal Range Reporting Structures for Categorical

    DEFF Research Database (Denmark)

    Larsen, Kasper Green; Walderveen, Freek van

    2013-01-01

    Range reporting on categorical (or colored) data is a well-studied generalization of the classical range reporting problem in which each of the N input points has an associated color (category). A query then asks to report the set of colors of the points in a given rectangular query range, which...... may be far smaller than the set of all points in the query range. We study two-dimensional categorical range reporting in both the word-RAM and I/O-model. For the I/O-model, we present two alternative data structures for three-sided queries. The first answers queries in optimal O(lgB N + K/B) I....../Os using O(N lg*N) space, where K is the number of distinct colors in the output, B is the disk block size, and lg*N is the iterated logarithm of N. Our second data structure uses linear space and answers queries in O(lg B N + lg(h) N + K/B) I/Os for any constant integer h ≥ 1. Here lg(1) N = lg N and lg...

  8. Self-reported previous knee injury and low knee function increase knee injury risk in adolescent female football

    DEFF Research Database (Denmark)

    Clausen, M B; Tang, L; Zebis, M K

    2015-01-01

    Knee injuries are common in adolescent female football. Self-reported previous knee injury and low Knee injury and Osteoarthritis Outcome Score (KOOS) are proposed to predict future knee injuries, but evidence regarding this in adolescent female football is scarce. The aim of this study...... was to investigate self-reported previous knee injury and low KOOS subscale score as risk factors for future knee injuries in adolescent female football. A sample of 326 adolescent female football players, aged 15-18, without knee injury at baseline, were included. Data on self-reported previous knee injury and KOOS...... questionnaires were collected at baseline. Time-loss knee injuries and football exposures were reported weekly by answers to standardized text-message questions, followed by injury telephone interviews. A priori, self-reported previous knee injury and low KOOS subscale scores (

  9. Use of high-resolution accurate mass spectrometry to detect reported and previously unreported cannabinomimetics in "herbal high" products.

    Science.gov (United States)

    Hudson, Simon; Ramsey, John; King, Les; Timbers, Sarah; Maynard, Steve; Dargan, Paul I; Wood, David M

    2010-06-01

    A range of "Herbal High" products were tested for synthetic cannabinoids (cannabinomimetics) to qualitatively determine and compare their individual and relative content. Liquid chromatography-high resolution accurate mass spectrometry was used to rapidly screen samples for a range of cannabinomimetics using mono-isotopic masses derived from the elemental composition of target analytes. A screening database of over 140 compounds was rapidly created. This approach, combined with further tandem mass spectrometric experiments, also facilitated the detection and identification of compounds for which reference materials were not available. Previously reported cannabinomimetics, including JWH-018 and CP47,497 and its homologues, were detected in varying relative proportions along with several tentatively identified unreported cannabinomimetics. In some countries, the decision has been made to include these substances within their drug control legislation, and other countries are considering similar action. The currently applied drug screening techniques are unlikely to be effective in providing scientific evidence to support their identification in seized products. The application of high-resolution accurate mass spectrometry offers a solution. In addition, the technology provides a relatively simple and quick method for screening products, building substance databases, and even identifying novel substances using a combination of accurate mass derived elemental composition and fragment ions combined with fragmentation prediction software.

  10. Absence of psilocybin in species of fungi previously reported to contain psilocybin and related tryptamine derivatives

    OpenAIRE

    Stijve, T.; Kuyper, Th.W.

    1988-01-01

    Seven taxa of agarics reported in literature to contain psilocybin (viz. Psathyrella candolleana, Gymnopilus spectabilis, G. fulgens, Hygrocybe psittacina var. psittacina and var. californica, Rickenella fibula, R. swartzii) have been analysed for psilocybin and related tryptamines with negative results.

  11. Absence of psilocybin in species of fungi previously reported to contain psilocybin and related tryptamine derivatives

    NARCIS (Netherlands)

    Stijve, T.; Kuyper, Th.W.

    1988-01-01

    Seven taxa of agarics reported in literature to contain psilocybin (viz. Psathyrella candolleana, Gymnopilus spectabilis, G. fulgens, Hygrocybe psittacina var. psittacina and var. californica, Rickenella fibula, R. swartzii) have been analysed for psilocybin and related tryptamines with negative

  12. A previously unreported variant of the synostotic sagittal suture: Case report and review of salient literature

    Directory of Open Access Journals (Sweden)

    Madison Budinich

    2016-12-01

    Conclusion: To our knowledge, a synostotic sagittal suture has not been reported that extended posteriorly it involve the occipital bone. Those who interpret imaging or operate on this part of the skull should consider such a variation.

  13. Giant prostatic hyperplasia: report of a previously asymptomatic man presenting with gross hematuria and hypovolemic shock

    OpenAIRE

    Wroclawski, Marcelo Langer; Carneiro, Ariê; Tristão, Rodrigo Alves; Sakuramoto, Paulo Kouiti; Youssef, Jorg Daoud Merched; Lopes Neto, Antonio Correa; Santiago, Lucila Heloísa Simardi; Pompeo, Antonio Carlos Lima

    2015-01-01

    Giant prostatic hyperplasia is a rare condition characterized by very high volume benign prostatic enlargement (>500g). Few cases have been reported so far and most of them are associated with severe lower urinary symptoms. We report the first case of asymptomatic giant prostatic hyperplasia in an elderly man who had a 720g prostate adenoma, sudden gross hematuria and hypovolemic shock. The patient was successfully treated with open transvesical prostatectomy and had an uneventful postoperati...

  14. 1993 site environmental report Tonopah Test Range, Tonopah, Nevada

    Energy Technology Data Exchange (ETDEWEB)

    Culp, T.; Howard, D.; McClellan, Y.

    1994-10-01

    This report summarizes the environmental surveillance activities conducted by Sandia National Laboratories, the US Environmental Protection Agency, and Reynolds Electrical and Engineering Company for the Tonopah Test Range operated by Sandia National Laboratories. Sandia National Laboratories` responsibility for environmental monitoring results extend to those activities performed by Sandia National Laboratories or under its direction. Results from other environmental monitoring activities are included to provide a measure of completeness in reporting. Other environmental compliance programs such as the National Environmental Policy Act of 1969, environmental permits, and environmental restoration and waste management programs are also included in this report, prepared for the US Department of Energy in compliance with DOE Order 5400.1.

  15. A general approach for cache-oblivious range reporting and approximate range counting

    DEFF Research Database (Denmark)

    Afshani, Peyman; Hamilton, Chris; Zeh, Norbert

    2010-01-01

    of points in the query range. As a corollary, we also obtain the first approximate 3-d halfspace range counting and 3-d dominance counting data structures with a worst-case query time of O(log(N/K)) in internal memory. An easy but important consequence of our main result is the existence of -space cache...... counting queries. This class includes three-sided range counting in the plane, 3-d dominance counting, and 3-d halfspace range counting. The constructed data structures use linear space and answer queries in the optimal query bound of O(logB(N/K)) block transfers in the worst case, where K is the number......-oblivious data structures with an optimal query bound of O(logBN+K/B) block transfers for the reporting versions of the above problems. Using standard reductions, these data structures allow us to obtain the first cache-oblivious data structures that use almost linear space and achieve the optimal query bound...

  16. Groin Problems in Male Soccer Players Are More Common Than Previously Reported

    DEFF Research Database (Denmark)

    Harøy, Joar; Clarsen, Ben; Thorborg, Kristian

    2017-01-01

    BACKGROUND: The majority of surveillance studies in soccer have used a time-loss injury definition, and many groin problems result from overuse, leading to gradually increasing pain and/or reduced performance without necessarily causing an absence from soccer training or match play. Thus, the mag......BACKGROUND: The majority of surveillance studies in soccer have used a time-loss injury definition, and many groin problems result from overuse, leading to gradually increasing pain and/or reduced performance without necessarily causing an absence from soccer training or match play. Thus...... surveillance method developed to capture acute and overuse problems. STUDY DESIGN: Descriptive epidemiology study. METHODS: We registered groin problems during a 6-week period of match congestion using the Oslo Sports Trauma Research Center Overuse Injury Questionnaire. A total of 240 players from 15 teams...... for senior male soccer players. CONCLUSION: We found a high prevalence of groin problems among male soccer players during a period with match congestion. Time-loss definition as used in previous injury surveillance studies captured only one-third of the male groin problems registered with the new method...

  17. [Lessons from abroad. Current and previous crisis in other countries. SESPAS report 2014].

    Science.gov (United States)

    Rivadeneyra-Sicilia, Ana; Minué Lorenzo, Sergio; Artundo Purroy, Carlos; Márquez Calderón, Soledad

    2014-06-01

    The evidence available on the impact of previous crises on health reveals different patterns attributable to study designs, the characteristics of each crisis, and other factors related to the socioeconomic and political context. There is greater consensus on the mediating role of government policy responses to financial crises. These responses may magnify or mitigate the adverse effects of crises on population health. Some studies have shown a significant deterioration in some health indicators in the context of the current crisis, mainly in relation to mental health and communicable diseases. Alcohol and tobacco use have also declined in some European countries. In addition, this crisis is being used by some governments to push reforms aimed at privatizing health services, thereby restricting the right to health and healthcare. Specifically, action is being taken on the three axes that determine health system financing: the population covered, the scope of services, and the share of the costs covered. These measures are often arbitrarily implemented based on ideological decisions rather than on the available evidence and therefore adverse consequences are to be expected in terms of financial protection, efficiency, and equity. Copyright © 2013 SESPAS. Published by Elsevier Espana. All rights reserved.

  18. Increased Symptom Reporting in Young Athletes Based on History of Previous Concussions.

    Science.gov (United States)

    Moser, Rosemarie Scolaro; Schatz, Philip

    2017-01-01

    Research documents increased symptoms in adolescents with a history of two or more concussions. This study examined baseline evaluations of 2,526 younger athletes, ages 10 to 14. Between-groups analyses examined Post Concussion Symptom Scale symptoms by concussion history group (None, One, Two+) and clusters of Physical, Cognitive, Emotional, and Sleep symptoms. Healthy younger athletes with a concussion history reported greater physical, emotional, and sleep-related symptoms than those with no history of concussion, with a greater endorsement in physical/sleep symptom clusters. Findings suggest younger athletes with a history of multiple concussions may experience residual symptoms.

  19. Preliminary data suggest rates of male military sexual trauma may be higher than previously reported.

    Science.gov (United States)

    Sheppard, Sean C; Hickling, Edward J; Earleywine, Mitch; Hoyt, Tim; Russo, Amanda R; Donati, Matthew R; Kip, Kevin E

    2015-11-01

    Stigma associated with disclosing military sexual trauma (MST) makes estimating an accurate base rate difficult. Anonymous assessment may help alleviate stigma. Although anonymous research has found higher rates of male MST, no study has evaluated whether providing anonymity sufficiently mitigates the impact of stigma on accurate reporting. This study used the unmatched count technique (UCT), a form of randomized response techniques, to gain information about the accuracy of base rate estimates of male MST derived via anonymous assessment of Operation Enduring Freedom (OEF)/Operation Iraqi Freedom (OIF) combat veterans. A cross-sectional convenience sample of 180 OEF/OIF male combat veterans, recruited via online websites for military populations, provided data about history of MST via traditional anonymous self-report and the UCT. The UCT revealed a rate of male MST more than 15 times higher than the rate derived via traditional anonymous assessment (1.1% vs. 17.2%). These data suggest that anonymity does not adequately mitigate the impact of stigma on disclosure of male MST. Results, though preliminary, suggest that published rates of male MST may substantially underestimate the true rate of this problem. The UCT has significant potential to improve base rate estimation of sensitive behaviors in the military. (c) 2015 APA, all rights reserved).

  20. Angiosarcoma in previously irradiated breast in patient with Li-Fraumeni syndrome. A case report

    Directory of Open Access Journals (Sweden)

    Oséias Vargas Barbosa

    Full Text Available CONTEXT: Li-Fraumeni syndrome is a rare disease with an autosomal dominant inheritance pattern and high penetrance that defines a 50% chance of developing cancer before the age of 30 years, including cases of breast sarcoma. Patients with this syndrome who require radiotherapy have an increased risk of developing secondary malignancies including angiosarcomas. CASE REPORT: This was a case report on a female patient with Li-Fraumeni syndrome. In October 2005, she was diagnosed with invasive ductal carcinoma of the right breast and underwent sectorectomy. She then received chemotherapy and adjuvant radiotherapy. Trastuzumab and tamoxifen were also part of the treatment. She recently sought care at our hospital, complaining of hyperemia and nodulation in the right breast, and underwent surgical resection that revealed epithelioid angiosarcoma. CONCLUSIONS: When genetic predisposition due to Li-Fraumeni syndrome is documented, the therapy should be adapted so as to minimize the risk. Thus, conservative surgical treatments should be avoided and mastectomy without radiation should be prioritized. In cases in which use of radiotherapy is justified, patients should be followed up intensively.

  1. Leiomyosarcoma of the Prostate: Case Report and Review of 54 Previously Published Cases

    Directory of Open Access Journals (Sweden)

    Gerasimos P. Vandoros

    2008-01-01

    Full Text Available Prostate leiomyosarcoma is an extremely rare and highly aggressive neoplasm that accounts for less than 0.1% of primary prostate malignancies. We present a patient with primary leiomyosarcoma of the prostate and review 54 cases reported in the literature to discuss the clinical, diagnostic and therapeutic aspects of this uncommon tumor. Median survival was estimated at 17 months (95% C.I. 20.7–43.7 months and the 1-, 3-, and 5-year actuarial survival rates were 68%, 34%, and 26%, respectively. The only factors predictive of long-term survival were negative surgical margins and absence of metastatic disease at presentation. A multidisciplinary approach is necessary for appropriate management of this dire entity.

  2. Tonopah Test Range Post-Closure Inspection Annual Report, Tonopah Test Range, Nevada, Calendar Year 2002

    Energy Technology Data Exchange (ETDEWEB)

    R. B. Jackson

    2003-08-01

    This Post-Closure Inspection Annual Report provides documentation of the semiannual inspections conducted at the following Corrective Action Units (CAU)s: CAU 400: Bomblet Pit and Five Points Landfill; CAU 404: Roller Coaster Lagoons and Trench; CAU 407: Roller Coaster RadSafe Area; CAU 424: Area 3 Landfill Complexes; CAU 426: Cactus Spring Waste Trenches; CAU 427: Septic Waste Systems 2, 6; and CAU 453: Area 9 UXO Landfill, all located at the Tonopah Test Range, Nevada. Post-closure inspections are not required at CAU 400 but are conducted to monitor vegetation and fencing at the site. Site inspections were conducted in May and November 2002. All site inspections were made after Nevada Division of Environmental Protection (NDEP) approval of the appropriate Closure Report (CR), excluding CAU 400 which did not require a CR, and were conducted in accordance with the Post-Closure Inspection Plans in the NDEP-approved CRs. Post-closure inspections conducted during 2002 identified several areas requiring maintenance/repairs. Maintenance work and proposed additional monitoring are included in the appropriate section for each CAU. This report includes copies of the Post-Closure Inspection Plans, Post-Closure Inspection Checklists, copies of the field notes, photographs, and the Post-Closure Vegetative Monitoring Report. The Post-Closure Inspection Plan for each CAU is located in Attachment A. Post-Closure Inspection Checklists are in Attachment B. Copies of the field notes from each inspection are included in Attachment C. Attachment D consists of the photographic logs and photographs of the sites. The post-closure vegetative monitoring report for calendar year 2002 is included in Attachment E.

  3. 1998 Annual Site Environmental Report Tonopah Test Range, Nevada

    Energy Technology Data Exchange (ETDEWEB)

    Duncan, D.K.; Fink, C.H.; Sanchez, R.V.

    1999-09-01

    Sandia National Laboratories (SNL) operates the Tonopah Test Range (TTR) for the Department of Energy (DOE) Weapons Ordnance Program. This annual report (calendar year 1998) summarizes the compliance status to environmental regulations applicable at the site including those statutes that govern air and water quality, waste management cleanup of contaminated areas, control of toxic substances, and adherence to requirements as related to the National Environmental Policy Act (NEPA). In compliance with DOE orders, SNL also conducts environmental surveillance for radiological and nonradiological contaminants. SNL's responsibility for environmental surveillance at TTR extends only to those areas where SNL activities are carried out. Annual radiological and nonradiological routine releases and unplanned releases (occurrences) are also summarized. This report has been prepared in accordance with DOE Order 5400.1, General Environmental Protection Program (DOE 1990a).

  4. 1997 annual site environmental report, Tonopah Test Range, Nevada

    Energy Technology Data Exchange (ETDEWEB)

    Culp, Todd; Duncan, Dianne (ed.); Forston, William; Sanchez, Rebecca (ed.)

    1998-08-01

    Sandia National Laboratories (SNL) operates the Tonopah Test Range for the Department of Energy's (DOE) Weapons Ordnance Program. Thes annual report (calendar year 1997) summarizes the compliance status to environmental regulations applicable at the site including those statutes that govern air and water quality, waste management, cleanup of contaminated areas, control of toxic substances, and adherence to requirements as related to the National Environmental Policy Act. In compliance with DOE orders, SNL also conducts environmental surveillance for radiological and nonradiological contaminants. SNL's responsibility for environmental surveillance extends only to those activities performed by SNL or under its direction. Annual radiological and nonradiological routine releases and unplanned releases (occurrences) are also summarized. This report has been prepared as required by DOE Order 5400.1, General Environmental Protection Program.

  5. 24 CFR 1710.558 - Previously accepted state filings-notice of revocation rights on property report cover page.

    Science.gov (United States)

    2010-04-01

    ... FOR HOUSING-FEDERAL HOUSING COMMISSIONER, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT (INTERSTATE LAND... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Previously accepted state filings-notice of revocation rights on property report cover page. 1710.558 Section 1710.558 Housing and Urban...

  6. A Near-Fatal Infection with Oseltamivir-Resistant Seasonal Influenza A in a Previously Healthy Child: Case Report

    Directory of Open Access Journals (Sweden)

    Jesse Papenburg

    2009-01-01

    Full Text Available A case of near-fatal oseltamivir-resistant seasonal influenza A infection in a previously healthy four-year-old boy is reported. This case highlights three important points for physicians: oseltamivir-resistant influenza A (H1N1 has recently emerged in North America; contrary to previously held beliefs, such strains are capable of causing severe disease in healthy children; and given this change in epidemiology, clinicians caring for children with severe seasonal influenza A infection should consider empiric dual therapy with oseltamivir and amantadine.

  7. Multiple Anesthetic Drug Sensitization in a Hairdresser With Previous Immediate-Type Hypersensitivity to Penicillin: A Case Report.

    Science.gov (United States)

    Petrişor, Cristina; Gherman, Nadia; Sfichi, Manuela; Mureşan, Marius; Hagău, Natalia

    2017-09-01

    Risk factors for intraoperative immediate-type hypersensitivity reactions may require allergological evaluation. We report the case of a hairdresser with a positive history of penicillin hypersensitivity and anaphylactic shock during previous general anesthesia, whose in vivo and in vitro allergy tests were positive for neuromuscular blocking agents, opioids, and midazolam. Immediate-type hypersensitivity reactions to antibiotics and professional exposure to hairdressing products might induce simultaneous cross-sensitization to multiple drugs that are commonly used during general anesthesia.

  8. Squamous cell carcinoma in association with dental implants: an assessment of previously hypothesized carcinogenic mechanisms and a case report.

    Science.gov (United States)

    Bhatavadekar, Neel B

    2012-12-01

    Although dental implants have seen tremendous clinical success over the past few decades, there are some worrying reports in literature describing squamous cell carcinoma (SCC) in close association with dental implants. This article also provides a critical assessment of the published literature relating to the presence of carcinoma in association with dental implants, analyzing the previously published and hypothesized carcinogenic responses to an implant, to try and come to a conclusion regarding the plausibility and clinical risk for cancer formation in association with dental implants. An unusual case of an SCC noted in close proximity to a dental implant is also presented. A systematic search was conducted using Medline (PubMed), Cochrane Database, and Google Scholar with the search terms "cancer," "squamous cell carcinoma," "dental implant," "SCC," "peri-implantitis," "oral cancer," and "implantology" and using multiple combinations using Boolean operators "or" and "and." The search was not limited to dental literature; orthopedic and biomedical literature was also included. The results were then hand screened to pick out the relevant articles. In total, 14 previous published reports were found, where 24 dental implants were reported to be associated with SCC. Not all the reported patients had a history of cancer, but contributory factors such as smoking were found. An analysis of the biological plausibility of previously proposed carcinogenic mechanisms, such as corrosion, metallic ion release, and particulate debris, did not support the etiologic role for dental implants in cancer development, and the standardized incidence ratio was found to be extremely low (0.00017). Peri-implantitis should be assessed cautiously in patients receiving implants who have a previous history of cancer. Dental implants are a safe treatment modality based on the published data, and any change in surgical protocol is not mandated.

  9. Root coverage of a previously restored tooth. A case report with a 7-year follow-up.

    Science.gov (United States)

    Corsair, Alexander

    2009-01-01

    This case report describes the treatment of a maxillary canine that had 4 mm of marginal gingival recession. The exposed root had been previously restored with a composite class 5 restoration. The restoration was removed and the root planed and demineralized. The root was then covered by a subepithelial connective tissue graft harvested from the palate. The flap was coronally positioned to completely cover the graft and exposed root. The healing was photographed post-operatively at one month, six months, and seven years. Root coverage increased to 100% after seven years. The zone of attached gingiva also increased.

  10. Robotic Placement of the FENIX Continence Restoration System in a Patient with Previous Radiation to the Pelvis: A Case Report.

    Science.gov (United States)

    Espinal, Mariana; DeStephano, Christopher C; Guha, Paulami; Gajarawala, Shilpa P; Chen, Anita H; Pettit, Paul D

    2017-07-17

    Fecal incontinence (FI) is a disabling problem affecting women. Conservative treatment includes dietary modification, antimotility agents, and pelvic floor physical therapy. If conservative medical management is unsuccessful, surgical intervention may be required. Surgical options include rectal sphincteroplasty, bulking agent injection, radiofrequency anal sphincter remodeling, and sacral nerve stimulation therapy. Recently, a new therapy for FI, the FENIX Continence Restoration System (Torax Medical, Inc., Shoreview, MN), has become available. The FENIX device is placed through a perineal incision; however, pelvic radiation and previous anal carcinoma are both contraindications. We report the case of a 62-year-old woman with FI after anal carcinoma. Treatment included surgery, chemotherapy, and pelvic radiation. Initially, she was treated with conservative therapy and sacral nerve stimulation, which were only partially effective. A physical examination showed perineal skin changes consistent with previous radiation, which increased the patient's risk of infection and a nonhealing wound. Therefore, a robotic approach was used to place the FENIX device and improve the patient's quality of life. Our case sets a precedent for expanding the treatment options of FI in patients with previous pelvic radiation and using a robotic approach for the placement of the FENIX device. Copyright © 2017 American Association of Gynecologic Laparoscopists. Published by Elsevier Inc. All rights reserved.

  11. Range Information Systems Management (RISM) Phase 1 Report

    Science.gov (United States)

    Bastin, Gary L.; Harris, William G.; Nelson, Richard A.

    2002-01-01

    RISM investigated alternative approaches, technologies, and communication network architectures to facilitate building the Spaceports and Ranges of the future. RISM started by document most existing US ranges and their capabilities. In parallel, RISM obtained inputs from the following: 1) NASA and NASA-contractor engineers and managers, and; 2) Aerospace leaders from Government, Academia, and Industry, participating through the Space Based Range Distributed System Working Group (SBRDSWG), many of whom are also; 3) Members of the Advanced Range Technology Working Group (ARTWG) subgroups, and; 4) Members of the Advanced Spaceport Technology Working Group (ASTWG). These diverse inputs helped to envision advanced technologies for implementing future Ranges and Range systems that builds on today s cabled and wireless legacy infrastructures while seamlessly integrating both today s emerging and tomorrow s building-block communication techniques. The fundamental key is to envision a transition to a Space Based Range Distributed Subsystem. The enabling concept is to identify the specific needs of Range users that can be solved through applying emerging communication tech

  12. Fort Peck Game Range: Narrative report: September - December 1961

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This narrative report for Fort Peck NWR and the easement refuges outlines Refuge accomplishments from September through December of 1961. The report begins by...

  13. Fort Peck Game Range: Narrative report: January - April, 1957

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This narrative report for Fort Peck NWR and the easement refuges outlines Refuge accomplishments from January through April of 1957. The report begins by summarizing...

  14. [Fort Peck Game Range: Narrative report: August-October, 1940

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This narrative report for Fort Peck NWR outlines Refuge accomplishments from August through October of 1940. The report begins by summarizing the weather conditions...

  15. Fort Peck Game Range: Narrative report: January - April 1960

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This narrative report for Fort Peck NWR and the easement refuges outlines Refuge accomplishments from January through April of 1960. The report begins by summarizing...

  16. Global history of the ancient monocot family Araceae inferred with models accounting for past continental positions and previous ranges based on fossils.

    Science.gov (United States)

    Nauheimer, Lars; Metzler, Dirk; Renner, Susanne S

    2012-09-01

    The family Araceae (3790 species, 117 genera) has one of the oldest fossil records among angiosperms. Ecologically, members of this family range from free-floating aquatics (Pistia and Lemna) to tropical epiphytes. Here, we infer some of the macroevolutionary processes that have led to the worldwide range of this family and test how the inclusion of fossil (formerly occupied) geographical ranges affects biogeographical reconstructions. Using a complete genus-level phylogeny from plastid sequences and outgroups representing the 13 other Alismatales families, we estimate divergence times by applying different clock models and reconstruct range shifts under different models of past continental connectivity, with or without the incorporation of fossil locations. Araceae began to diversify in the Early Cretaceous (when the breakup of Pangea was in its final stages), and all eight subfamilies existed before the K/T boundary. Early lineages persist in Laurasia, with several relatively recent entries into Africa, South America, South-East Asia and Australia. Water-associated habitats appear to be ancestral in the family, and DNA substitution rates are especially high in free-floating Araceae. Past distributions inferred when fossils are included differ in nontrivial ways from those without fossils. Our complete genus-level time-scale for the Araceae may prove to be useful for ecological and physiological studies. © 2012 The Authors. New Phytologist © 2012 New Phytologist Trust.

  17. 2006 Long Range Development Plan Final Environmental ImpactReport

    Energy Technology Data Exchange (ETDEWEB)

    Philliber, Jeff

    2007-01-22

    This environmental impact report (EIR) has been prepared pursuant to the applicable provisions of the California Environmental Quality Act (CEQA) and its implementing guidelines (CEQA Guidelines), and the Amended University of California Procedures for Implementation of the California Environmental Quality Act (UC CEQA Procedures). The University of California (UC or the University) is the lead agency for this EIR, which examines the overall effects of implementation of the proposed 2006 Long Range Development Plan (LRDP; also referred to herein as the 'project' for purposes of CEQA) for Lawrence Berkeley National Laboratory (LBNL; also referred to as 'Berkeley Lab,' 'the Laboratory,' or 'the Lab' in this document). An LRDP is a land use plan that guides overall development of a site. The Lab serves as a special research campus operated by the University employees, but it is owned and financed by the federal government and as such it is distinct from the UC-owned Berkeley Campus. As a campus operated by the University of California, the Laboratory is required to prepare an EIR for an LRDP when one is prepared or updated pursuant to Public Resources Code Section 21080.09. The adoption of an LRDP does not constitute a commitment to, or final decision to implement, any specific project, construction schedule, or funding priority. Rather, the proposed 2006 LRDP describes an entire development program of approximately 980,000 gross square feet of new research and support space construction and 320,000 gross square feet of demolition of existing facilities, for a total of approximately 660,000 gross square feet of net new occupiable space for the site through 2025. Specific projects will undergo CEQA review at the time proposed to determine what, if any, additional review is necessary prior to approval. As described in Section 1.4.2, below, and in Chapter 3 of this EIR (the Project Description), the size of the project has been

  18. Root coverage of a previously restored tooth. A case report with a 7-year follow-up

    Directory of Open Access Journals (Sweden)

    Alexander Corsair

    2009-06-01

    Full Text Available Alexander CorsairPrivate Practice, RockvilleCentre, NY, USAAbstract: This case report describes the treatment of a maxillary canine that had 4 mm of marginal gingival recession. The exposed root had been previously restored with a composite class 5 restoration. The restoration was removed and the root planed and demineralized. The root was then covered by a subepithelial connective tissue graft harvested from the palate. The flap was coronally positioned to completely cover the graft and exposed root. The healing was photographed post-operatively at one month, six months, and seven years. Root coverage increased to 100% after seven years. The zone of attached gingiva also increased.Keywords: coronally positioned, subepithelial, connective tissue graft, keritinized gingiva, creeping reattachment

  19. Leaching from the stratum corneum does not explain the previously reported elevated potassium ion concentration in sweat.

    Science.gov (United States)

    Buono, Michael J; Stone, Michael; Cannon, Daniel T

    2016-03-01

    The purpose of this study was to determine if K+ is leached from the stratum corneum when sweat is present on the skin's surface. The results will help address whether sweat [K+] previously reported in the literature are artifactually elevated as a result of K+ leaching. Twelve (six female, six male) healthy volunteers participated in this study. After thorough skin cleansing and preparation with isopropyl alcohol and high-performance liquid chromatography-grade distilled water, three sites were chosen and a 50 μL drop of artificial sweat was pipetted directly onto the skin. The artificial sweat had a [K+] of 4 mEq·L-1, an osmolality of 120 mosm·L-1, and a pH of 6.0. Immediately following, a clear plastic cover slip (~6 cm2) with a shallow 0.8 cm2 convex impression in the center was applied over each drop, preventing evaporation. Each sample was allowed to sit on the forearm, under the plastic cover slip, for 10 min. The mean (±SD) [K+] in 'artificial' sweat not exposed to the skin was measured to be 4.2±0.4 mEq·L-1. After 10 min of exposure to the stratum corneum of the forearm, the artificial sweat had a mean (±SD) [K+] of 3.9±0.3 mEq·L-1. There was no significant difference (p>0.05) in the [K+] between the control artificial sweat and the samples collected after 10 min of exposure to forearm skin. These results do not support the hypothesis that significant K+ leaching from the stratum corneum into standing sweat is the cause for the previously reported elevated sweat [K+].

  20. Netherlands Army Long Range Anti Armour Study - Status Report

    NARCIS (Netherlands)

    Schagen, P.A.B. van

    1989-01-01

    At the end of the nineties the munition for the TOW weapon system in use at The Netherlands army, has to be replaced. The Life of Type of The Tow carrier ends in 2005. The long range anti armour study is to gain insight into the possibilities and limitations for the Netherlands army to deploy future

  1. A RAPD based study revealing a previously unreported wide range of mesophilic and thermophilic spore formers associated with milk powders in China.

    Science.gov (United States)

    Sadiq, Faizan A; Li, Yun; Liu, TongJie; Flint, Steve; Zhang, Guohua; He, GuoQing

    2016-01-18

    Aerobic spore forming bacteria are potential milk powder contaminants and are viewed as indicators of poor quality. A total of 738 bacteria, including both mesophilic and thermophilic, isolated from twenty-five powdered milk samples representative of three types of milk powders in China were analyzed based on the random amplified polymorphic DNA (RAPD) protocol to provide insight into species diversity. Bacillus licheniformis was found to be the most prevalent bacterium with greatest diversity (~43% of the total isolates) followed by Geobacillus stearothermophilus (~21% of the total isolates). Anoxybacillus flavithermus represented only 8.5% of the total profiles. Interestingly, actinomycetes represented a major group of the isolates with the predominance of Laceyella sacchari followed by Thermoactinomyces vulgaris, altogether comprising of 7.3% of the total isolates. Out of the nineteen separate bacterial species (except five unidentified groups) recovered and identified from milk powders, twelve proved to belong to novel or previously unreported species in milk powders. Assessment and characterization of the harmful effects caused by this particular micro-flora on the quality and safety of milk powders will be worth doing in the future. Copyright © 2015 Elsevier B.V. All rights reserved.

  2. An Attempt at the Northward Extension of the Breeding Range of the Atlantic Loggerhead Turtle by Egg Transplant Progress Report #4

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The object of this study is to attempt to extend the breeding range of the Atlantic Loggerhead Turtle northward to some of its reported previous range along the...

  3. An Attempt at the Northward Extension of the Breeding Range of the Atlantic Loggerhead Turtle by Egg Transplant Progress Report #2

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The object of this study is to attempt to extend the breeding range of the Atlantic Loggerhead Turtle northward to some of its reported previous range along the...

  4. Futures/Long-Range Planning Group. Periodic Report 7,

    Science.gov (United States)

    1982-11-01

    27 interface for 21st century travelers. In a cashless , checkless society , Asimov envisages that travelers will have plastic devices (similar to...are: Antarctica, America’s aging population, divided societies , American-English, ethnotronics, and long-range planning. An introductory page presents...States can be reasonably projected for the next 50 years because projections depend on death rates and not on birth rates.󈧐 Increasingly, US society will

  5. 1995 Site environmental report Tonopah Test Range, Tonopah, Nevada

    Energy Technology Data Exchange (ETDEWEB)

    Culp, T. [Sandia National Lab., Albuquerque, NM (United States); Forston, W. [Kirk-Mayer, Inc., Tonopah, NV (United States)

    1996-09-01

    This report summarizes the environmental surveillance activities conducted by Sandia National Laboratories. Sandia National Laboratories` responsibility for environmental surveillance results extends to those activities performed by Sandia National Laboratories or under its direction. Results from other organizations environmental surveillance activities are included to provide a measure of completeness. Other environmental compliance programs such as the National Environmental Policy Act of 1969, environmental permits, and environmental restoration and waste management programs are also included in this report, prepared for the U.S. Department of Energy (DOE) in compliance with DOE Order 5400.1.

  6. Parameter-free Locality Sensitive Hashing for Spherical Range Reporting

    DEFF Research Database (Denmark)

    Ahle, Thomas Dybdahl; Pagh, Rasmus; Aumüller, Martin

    2017-01-01

    by standard LSH) and easy queries such as those where the number of points to report is a constant fraction of S, or where almost all points in S are far away from the query point. In contrast, known data structures fix LSH parameters based on certain parameters of the input alone. The algorithm has expected...

  7. 8th Annual report 1999. UN ECE convention on long-range transboundary air pollution

    Energy Technology Data Exchange (ETDEWEB)

    Kleemola, S.; Forsius, M. [eds.

    1999-07-01

    The Integrated Monitoring Programme (ICP IM) is part of the Effects Monitoring Strategy under the UN ECE Convention on Long-Range Transboundary Air Pollution. The main aim of ICP IM is to provide a framework to observe and understand the complex changes occurring in the external environment. This report summarizes the work carried out by the ICP IM Programme Centre and several collaborating institutes. The emphasis of the report is in the work done during the programme year 1998/99 including: - a short summary of previous data assessments - a short status report of the ICP IM activities, content of the IM database, and the present geographical coverage of the monitoring network - a documentation of the scientific strategies to carry out data assessment on two priority topics: - assessment of heavy metal pools and fluxes - assessment of cause-effect relationships for understorey vegetation - a description of the WATBAL-model for estimating monthly water balance components, including soil water fluxes. (orig.)

  8. Misoprostol for miscarriage management in a woman with previous five cesarean deliveries: a case report and literature review

    Directory of Open Access Journals (Sweden)

    AlSaad D

    2017-05-01

    Full Text Available Doua AlSaad,1,2 Sawsan Alobaidly,3 Palli Abdulrouf,1 Binny Thomas,4,5 Afif Ahmed,1 Moza AlHail1 1Department of Pharmacy, Women’s Hospital, Hamad Medical Corporation, Doha, Qatar; 2Public Health Program, London School of Hygiene and Tropical Medicine, University of London, UK; 3Department of Obstetrics and Gynecology, Women’s Hospital, 4Clinical Support Service Unit, Hamad Medical Corporation, Doha, Qatar; 5Pharmacy and Life Sciences Research Institute, Robert Gordon University, Aberdeen, Scotland Background: Misoprostol is an effective medical method for the management of pregnancy loss. However, data on its efficacy and safety in women with previous cesarean deliveries are limited.Case presentation: We report a 36-year-old patient, gravida 11 para 6, with a diagnosis of missed miscarriage at 15 weeks of gestation. The patient had a significant obstetric history of previous five cesarean deliveries and uterine rupture. Following patient counseling about the medical and surgical options of managing her miscarriage, the patient opted for medical method. Low-dose misoprostol of 100 µg was inserted vaginally and repeated again after 6 hours. The patient had an uneventful complete miscarriage following the second dose of misoprostol. No uterine rupture, no extra vaginal bleeding, and no blood transfusion were observed.Conclusion: We conclude that adopting a low-dose misoprostol protocol could be potentially safe and effective in managing second trimester missed miscarriage in women with repeated cesarean deliveries and/or uterine rupture history. Further studies are needed to confirm these results. Keywords: cesarean section, uterine rupture, prostaglandin E1, misoprostol, second trimester, miscarriage, abortion

  9. The magnetic properties of transition metals on triangular lattices and the crystallography of new and previously reported sulfates

    Science.gov (United States)

    West, D. Vincent

    interactions and crystal structure by probing materials that were previously reported, and by expanding horizons through the discovery of novel crystal structures. It is of particular importance that the new crystal structures are made with readily available materials under relatively simple conditions. This implies that many chemically simple systems may remain to be found. In addition, it highlights the wonderful complexity of solid state chemistry that prevents the researcher from knowing a priori what crystal structures will form with a particular stoichiometry.

  10. Cruise Report: Long-Range Ocean Acoustic Propagation EXperiment (LOAPEX)

    Science.gov (United States)

    2005-04-01

    Long-range Owan ACoustic Propagation EXpewbitent LOAPEX L ý ý . OPXSRO So0 SVLAMVLA 40 KAA 20 M0 1 10 170 IN ISO 140 30 1010 Figure 1.2. LOAPEX assets...4.64 4.65 4.66 4.67 4.68 5000 > -5000 4.6 4.61 4.62 4.63 4.64 4.65 4.66 4.67 4.68 20 0 -I -20 4.6 4.61 4.62 4.63 4.64 4.65 4.66 4.67 4.68 .• 50001 1 1 1

  11. Face identity recognition in simulated prosthetic vision is poorer than previously reported and can be improved by caricaturing.

    Science.gov (United States)

    Irons, Jessica L; Gradden, Tamara; Zhang, Angel; He, Xuming; Barnes, Nick; Scott, Adele F; McKone, Elinor

    2017-08-01

    The visual prosthesis (or "bionic eye") has become a reality but provides a low resolution view of the world. Simulating prosthetic vision in normal-vision observers, previous studies report good face recognition ability using tasks that allow recognition to be achieved on the basis of information that survives low resolution well, including basic category (sex, age) and extra-face information (hairstyle, glasses). Here, we test within-category individuation for face-only information (e.g., distinguishing between multiple Caucasian young men with hair covered). Under these conditions, recognition was poor (although above chance) even for a simulated 40×40 array with all phosphene elements assumed functional, a resolution above the upper end of current-generation prosthetic implants. This indicates that a significant challenge is to develop methods to improve face identity recognition. Inspired by "bionic ear" improvements achieved by altering signal input to match high-level perceptual (speech) requirements, we test a high-level perceptual enhancement of face images, namely face caricaturing (exaggerating identity information away from an average face). Results show caricaturing improved identity recognition in memory and/or perception (degree by which two faces look dissimilar) down to a resolution of 32×32 with 30% phosphene dropout. Findings imply caricaturing may offer benefits for patients at resolutions realistic for some current-generation or in-development implants. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. Leptomeningeal myelomatosis in previously treated high-risk kappa light chain multiple myeloma: case report and literature review

    Directory of Open Access Journals (Sweden)

    Ohanian M

    2011-09-01

    Full Text Available Maro Ohanian1, James Alaly2, Stephen Samuel3, Christian Cable1, Kathleen Halka11Department of Hematology/Oncology, 2Department of Radiology, 3Department of Hematopathology, Scott and White Healthcare, The Texas A&M Health Science Center College of Medicine, Temple, Texas, USAObjective: To describe leptomeningeal myelomatosis (LM in previously treated high-risk kappa light chain multiple myeloma (MM and to review the literature.Case report: A 71-year-old female with previously treated kappa light chain myeloma presented with right lumbosacral discomfort. Magnetic resonance imaging (MRI of spine revealed multiple intradural masses involving the cauda equina, with mass effect on adjacent nerve roots. Brain MRI was unremarkable. Cerebrospinal fluid flow cytometry confirmed an abnormal population of plasma cells with kappa restriction; CD38, CD138, and CD56 were positive. She was originally diagnosed with kappa light chain myeloma 10 months earlier while hospitalized for anemia, thrombocytopenia, renal failure, and hypercalcemia. Bone marrow revealed plasma cell myeloma approaching 100% cellularity, with 92% plasma cells, atypical plasmacytoid cells with prominent nucleoli, and significant cytogenetic abnormalities: deleted 13, c-myc rearrangements, -X, +1. Treatments consisted of seven cycles of bortezomib with weekly dexamethasone. Her last dose had been 4 months earlier. After treatment, bone marrow demonstrated a complete remission with normal cytogenetics. Her clinical course had otherwise been indolent with a good hematologic response. After diagnosis of LM, therapy included focal external beam radiation to the cauda equina, weekly bortezomib and dexamethasone, intrathecal (IT cytarabine liposomal every 2 weeks for five doses, and monthly IT cytarabine liposomal thereafter. The cerebrospinal fluid gradually cleared on serial lumbar punctures and follow-up MRI demonstrated near complete resolution of the intradural masses. Five months after

  13. Genome-wide association study of electrocardiographic parameters identifies a new association for PR interval and confirms previously reported associations.

    Science.gov (United States)

    Sano, Motoaki; Kamitsuji, Shigeo; Kamatani, Naoyuki; Hong, Kyung-Won; Han, Bok-Ghee; Kim, Yeonjung; Kim, Jong Wook; Aizawa, Yoshiyasu; Fukuda, Keiichi

    2014-12-15

    Previous reports have described several associations of PR, QRS, QT and heart rate with genomic variations by genome-wide association studies (GWASs). In the present study, we examined the association of ∼2.5 million SNPs from 2994 Japanese healthy volunteers obtained from the JPDSC database with electrocardiographic parameters. We confirmed associations of PR interval, QRS duration and QT interval in individuals of Japanese ancestry with 11 of the 45 SNPs (6 of 20 for QT, 5 of 19 for PR and 0 of 6 for QRS) observed among individuals of European, African and Asian (Indian and Korean) ancestries. Those results indicate that many of the electrocardiographic associations with genes are shared by different ethnic groups including Japanese. Possible novel associations found in this study were validated by Korean data. As a result, we identified a novel association of SNP rs4952632[G] (maps near SLC8A1, sodium-calcium exchanger) (P = 7.595 × 10(-6)) with PR interval in Japanese individuals, and replication testing among Koreans confirmed the association of the same SNP with prolonged PR interval. Meta-analysis of the Japanese and Korean datasets demonstrated highly significant associations of SNP rs4952632[G] with a 2.325-ms (95% CI, 1.693-2.957 ms) longer PR interval per minor allele copy (P = 5.598 × 10(-13)). Cell-type-specific SLC8A1 knockout mice have demonstrated a regulatory role of sodium-calcium exchanger in automaticity and conduction in sinoatrial node, atrium and atrioventricular node. Our findings support a functional role of sodium-calcium exchanger in human atrial and atrioventricular nodal conduction as suggested by genetically modified mouse models. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  14. Analysis of over 10,000 Cases finds no association between previously reported candidate polymorphisms and ovarian cancer outcome

    DEFF Research Database (Denmark)

    White, Kristin L; Vierkant, Robert A; Fogarty, Zachary C

    2013-01-01

    Ovarian cancer is a leading cause of cancer-related death among women. In an effort to understand contributors to disease outcome, we evaluated single-nucleotide polymorphisms (SNP) previously associated with ovarian cancer recurrence or survival, specifically in angiogenesis, inflammation, mitosis...

  15. Refuge Narrative Report: September to December 1948: Kenai National Moose Range

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The 1948 September to December Narrative Report for the Kenai National Moose Range. The Kenai National Moose Range was established on December 16, 1941 after the...

  16. Dust Plume Modeling from Ranges and Maneuver Areas on Fort Bliss and the White Sands Missile Range: Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Chapman, Elaine G.; Barnard, James C.; Rutz, Frederick C.; Pekour, Mikhail S.; Rishel, Jeremy P.; Shaw, William J.

    2009-05-04

    The potential for air quality impacts from heavy mechanized vehicles operating on and between the unpaved main supply routes at Fort Bliss and White Sands Missile Range was investigated. This report details efforts by the staff of Pacific Northwest National Laboratory for the Fort Bliss Directorate of Environment in this investigation. Dust emission and dispersion from typical move-out activities occurring on the installations were simulated using the atmospheric modeling system DUSTRAN. Major assumptions associated with designing the modeling scenarios are summarized and results of simulations conducted under these assumptions are presented for four representative meteorological periods.

  17. Leptotrichia endocarditis: report of two cases from the International Collaboration on Endocarditis (ICE) database and review of previous cases

    NARCIS (Netherlands)

    Caram, L. B.; Linefsky, J. P.; Read, K. M.; Murdoch, D. R.; Lalani, T.; Woods, C. W.; Reller, L. B.; Kanj, S. S.; Premru, M. M.; Ryan, S.; Al-Hegelan, M.; Donnio, P. Y.; Orezzi, C.; Paiva, M. G.; Tribouilloy, C.; Watkin, R.; Harris, O.; Eisen, D. P.; Corey, G. R.; Cabell, C. H.; Petti, C. A.; Gordon, David; Devi, Uma; Spelman, Denis; van der Meer, Jan T. M.; Kauffman, Carol; Bradley, Suzanne; Armstrong, William; Giannitsioti, Efthymia; Giamarellou, Helen; Lerakis, Stamatios; del Rio, Ana; Moreno, Asuncion; Mestres, Carlos A.; Paré, Carlos; de la Maria, Cristina Garcia; de Lazzario, Elisa; Marco, Francesc; Gatell, Jose M.; Miró, José M.; Almela, Manel; Azqueta, Manuel; Jiménez-Expósito, Maria Jesús; de Benito, Natividad; Perez, Noel; Almirante, Benito; Fernandez-Hidalgo, Nuria; de Vera, Pablo Rodriguez; Tornos, Pilar; Falcó, Vicente; Claramonte, Xavier; Armero, Yolanda; Sidani, Nisreen; Kanj-Sharara, Souha; Kanafani, Zeina; Raglio, Annibale; Goglio, Antonio; Gnecchi, Fabrizio; Suter, Fredy; Valsecchi, Grazia; Rizzi, Marco; Ravasio, Veronica; Hoen, Bruno; Chirouze, Catherine; Leroy, Joel; Plesiat, Patrick; Bernard, Yvette; Casey, Anna; Lambert, Peter; Watkin, Richard; Elliott, Tom; FRCPath, D. Sc; Patel, Mukesh; Dismukes, William; Pan, Angelo; Caros, Giampiero; Tribouilloy, Amel Brahim Mathiron Christophe; Goissen, Thomas; Delahaye, Armelle; Delahaye, Francois; Vandenesch, Francois; Vizzotti, Carla; Nacinovich, Francisco M.; Marin, Marcelo; Trivi, Marcelo; Lombardero, Martin; Cortes, Claudia; Casabé, José Horacio; Altclas, Javier; Kogan, Silvia; Clara, Liliana; Sanchez, Marisa; Commerford, Anita; Hansa, Cass; Deetlefs, Eduan; Ntsekhe, Mpiko; Commerford, Patrick; Wray, Dannah; Steed, Lisa L.; Church, Preston; Cantey, Robert; Morris, Arthur; Holland, David; Murdoch, David; Graham, Katherine; Read, Kerry; Raymond, Nigel; Bridgman, Paul; Troughton, Richard; Lang, Selwyn; Chambers, Stephen; Kotsanas, Despina; Korman, Tony M.; Peterson, Gail; Purcell, Jon; Southern, Paul M.; Shah, Manisha; Bedimo, Roger; Reddy, Arjun; Levine, Donald; Dhar, Gaurav; Hanlon-Feeney, Alanna; Hannan, Margaret; Wang, Andrew; Cabell, Christopher H.; Woods, Christopher W.; Sexton, Daniel J.; Benjamin, Danny; Corey, G. Ralph; McDonald, Jay R.; Federspiel, Jeff; Engemann, John J.; Reller, L. Barth; Drew, Laura; Stryjewski, Martin; Morpeth, Susan; Lalani, Tahaniyat; Fowler, Vance; Chu, Vivian; Mazaheri, Bahram; Neuerburg, Carl; Naber, Christoph; Athan, Eugene; Henry, Margaret; Harris, Owen; Alestig, Eric; Olaison, Lars; Wikstrom, Lotta; Snygg-Martin, Ulrika; Francis, Johnson; Venugopal, K.; Nair, Lathi; Thomas, Vinod; Chaiworramukkun, Jaruwan; Pachirat, Orathai; Chetchotisakd, Ploenchan; Suwanich, Tewan; Kamarulzaman, Adeeba; Tamin, Syahidah Syed; Mueller Premru, Manica; Logar, Mateja; Lejko-Zupanc, Tatjana; Orezzi, Christina; Klein, John; Bouza, Emilio; Moreno, Mar; Rodríguez-Créixems, Marta; Marín, Mercedes; Fernández, Miguel; Muñoz, Patricia; Fernández, Rocío; Ramallo, Victor; Raoult, Didier; Thuny, Franck; Habib, Gilbert; Casalta, Jean-Paul; Fournier, Pierre-Edouard; Chipigina, Natalia; Kirill, Ozerecky; Vinogradova, Tatiana; Kulichenko, Vadim P.; Butkevich, O. M.; Lion, Christine; Selton-Suty, Christine; Alla, Francois; Coyard, Hélène; Doco-Lecompte, Thanh; Iarussi, Diana; Durante-Mangoni, Emanuele; Tripodi, Marie Françoise; Utili, Riccardo; Kumar, A. Sampath; Sharma, Gautam; Dickerman, Stuart A.; Street, Alan; Eisen, Damon Peter; McBryde, Emma Sue; Grigg, Leeanne; Abrutyn, Elias; Michelet, Christian; Tattevin, Pierre; Donnio, Pierre Yves; Fortes, Claudio Querido; de Janeiro, Rio; Edathodu, Jameela; Al-Hegelan, Mashael; Font, Bernat; Anguera, Ignasi; Guma, Joan Raimon; Cereceda, M.; Oyonarte, Miguel J.; Mella, Rodrigo Montagna; Garcia, Patricia; Jones, Sandra Braun; de Oliveira Ramos, Auristela Isabel; Paiva, Marcelo Goulart; de Medeiros Tranchesi, Regina Aparecida; Woon, Lok Ley; Tan, Ru-San; Rees, David; Kornecny, Pam; Lawrence, Richard; Dever, Robyn; Post, Jeffrey; Jones, Phillip; Ryan, Suzanne; Harkness, John; Feneley, Michael; Rubinstein, Ethan; Strahilewitz, Jacob; Ionac, Adina; Mornos, Cristian; Dragulescu, Stefan; Forno, Davide; Cecchi, Enrico; de Rosa, Francesco; Imazio, Massimo; Trinchero, Rita; Wiesbauer, Franz; Gattringer, Rainer; Deans, Greg; Andrasevic, Arjana Tambic; Barsic, Bruno; Klinar, Igor; Vincelj, Josip; Krajinovic, Vladimir; Cabell, Christopher; Stafford, Judy; Baloch, Khaula; Pappas, Paul; Redick, Thomas; Harding, Tina; Karchmer, A. W.; Bayer, Arnie; Durack, David T.; Phil, D.; Moreillon, Phillipe; Eykyn, Susannah

    2008-01-01

    Leptotrichia species typically colonize the oral cavity and genitourinary tract. We report the first two cases of endocarditis secondary to L. goodfellowii sp. nov. Both cases were identified using 16S rRNA gene sequencing. Review of the English literature revealed only two other cases of

  18. Postoperative beta irradiation in the treatment of pterygium. [Effectiveness and previously reported complications of use of /sup 90/Sr radioapplicators

    Energy Technology Data Exchange (ETDEWEB)

    Rahman, S.M.; Chung, C.K.; Constable, W.C.

    1979-07-01

    High recurrence rates are reported after surgical treatment of ptergyia. With the use of beta irradiation, the recurrence rate drops dramatically. This paper describes technic and dosage used in a group of patients receiving postoperative beta irradiation. Two thirds of these patients, however, had at least two surgical procedures. A recurrence rate of 3.5% was observed, with no apparent morbidity.

  19. National Bison Range: Refuge narrative report: September 1 to December 31, 1960

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This narrative report for National Bison Range outlines Refuge accomplishments from September through December of 1960. The report begins by summarizing the weather...

  20. National Bison Range: Refuge narrative report: May 1 to August 31, 1950

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This narrative report for National Bison Range outlines Refuge accomplishments from May through August of 1950. The report begins by summarizing the weather...

  1. National Bison Range: Refuge narrative report: May 1 to August 31, 1947

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This narrative report for National Bison Range outlines Refuge accomplishments from May through August of 1947. The report begins by summarizing the weather...

  2. National Bison Range: Refuge narrative report: May 1 to August 31, 1951

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This narrative report for National Bison Range outlines Refuge accomplishments from May through August of 1951. The report begins by summarizing the weather...

  3. National Bison Range: Refuge narrative report: May 1 to August 31, 1943

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This narrative report for National Bison Range outlines Refuge accomplishments from May through August of 1943. The report begins by summarizing the weather...

  4. Refuge narrative report January 1 to April 30, 1963 : Clarence Rhode National Wildlife Range

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This narrative report for Clarence Rhode National Wildlife Range outlines Refuge accomplishments from January through April of 1963. The report begins by summarizing...

  5. National Bison Range: Refuge narrative report: January 1 to April 30, 1950

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This narrative report for National Bison Range outlines Refuge accomplishments from January through April of 1950. The report begins by summarizing the weather...

  6. National Bison Range: Refuge narrative report: September 1 to December 31, 1951

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This narrative report for National Bison Range outlines Refuge accomplishments from September through December of 1951. The report begins by summarizing the weather...

  7. National Bison Range: Refuge narrative report: May 1 to August 31, 1953

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This narrative report for National Bison Range outlines Refuge accomplishments from May through August of 1953. The report begins by summarizing the weather...

  8. End-Of-Life Medical Spending In Last Twelve Months Of Life Is Lower Than Previously Reported

    DEFF Research Database (Denmark)

    French, Eric; McCauley, Jeremy; Aragon, Maria

    2017-01-01

    , the United States, and the Canadian province of Quebec to measure the composition and magnitude of medical spending in the three years before death. In all nine countries, medical spending at the end of life was high relative to spending at other ages. Spending during the last twelve months of life made up...... a modest share of aggregate spending, ranging from 8.5 percent in the United States to 11.2 percent in Taiwan, but spending in the last three calendar years of life reached 24.5 percent in Taiwan. This suggests that high aggregate medical spending is due not to last-ditch efforts to save lives...

  9. Case report of electronic cigarettes possibly associated with eosinophilic pneumonitis in a previously healthy active-duty sailor.

    Science.gov (United States)

    Thota, Darshan; Latham, Emi

    2014-07-01

    Electronic cigarettes (e-cigarettes) are a technology that has been touted as a safe and effective alternative to traditional cigarettes. There is, however, a paucity of literature showing the adverse outcomes of e-cigarettes and a correlation with acute eosinophilic pneumonia (AEP). To present a possible association between e-cigarettes and AEP. A 20-year-old previously healthy man was found to develop AEP after smoking an e-cigarette. He was treated with antibiotics and steroids and his symptoms improved. Though an alternative to traditional cigarettes, e-cigarettes can have unpredictable and potentially serious adverse effects. More research needs to be conducted to determine their safety. If seeing a patient in the ED with pulmonary symptoms after use of e-cigarettes, AEP should be considered in the differential. Published by Elsevier Inc.

  10. Bulimia nervosa patient diagnosed with previously unsuspected ADHD in adulthood: clinical case report, literature review, and diagnostic challenges.

    Science.gov (United States)

    Ioannidis, Konstantinos; Serfontein, Jaco; Müller, Ulrich

    2014-05-01

    There is increasing literature suggesting a link between attention-deficit hyperactivity disorder (ADHD) and eating disorders (EDs), especially bulimia nervosa. ADHD is under-diagnosed in girls and children of high intelligence are typically missed. We identified a case of a 23-year-old woman suffering from severe bulimia nervosa and previously unsuspected ADHD in adulthood; we diagnosed and treated her with extended-release methylphenidate. We performed a literature review on the ADHD and bulimia nervosa comorbidity. We discuss the reasons why her ADHD remained undiagnosed and the difficulties in diagnosing ADHD in patients with EDs. We suggest that identifying comorbid ADHD is crucial for these patients and argue for the use of a structured interview, collateral history and investigation of onset of symptoms to establish a diagnosis of ADHD in adults with bulimia nervosa. Comorbidities and overlap of symptomatology need to be taken into account. Copyright © 2013 Wiley Periodicals, Inc.

  11. Osseointegration Implant Post Coupling With External Prosthetic Limb – Continuation of Previous Case Reports “Stage III”

    OpenAIRE

    Ronald Hillock, MD; Danny Tatum, BCP; Edward Dolegowski, PT

    2014-01-01

    An ongoing update of the progress case report for the first patient treated with the Longitude™ osseointegration prosthesis implanted in an amputated residual femur is presented. The patient was given an intensive physical therapy program of strengthening and conditioning in anticipation of coupling to the external prosthesis. A custom prosthesis was fabricated based on the Plie’ 2.0 microprocessor knee system. The patient was then successfully trained on use and care of the prosthesis for am...

  12. Comprehensive Luciferase-Based Reporter Gene Assay Reveals Previously Masked Up-Regulatory Effects of miRNAs

    Directory of Open Access Journals (Sweden)

    Danae Campos-Melo

    2014-09-01

    Full Text Available MicroRNAs (miRNAs are small non-coding RNAs that regulate the majority of the transcriptome at a post-transcriptional level. Because of this critical role, it is important to ensure that the assays used to determine their functionality are robust and reproducible. Typically, the reporter gene assay in cell-based systems has been the first-line method to study miRNA functionality. In order to overcome some of the potential errors in interpretation that can be associated with this assay, we have developed a detailed protocol for the luciferase reporter gene assay that has been modified for miRNAs. We demonstrate that normalization against the effect of the miRNA and cellular factors on the luciferase coding sequence is essential to obtain the specific impact of the miRNA on the 3'UTR (untranslated region target. Our findings suggest that there is a real possibility that the roles for miRNA in transcriptome regulation may be misreported due to inaccurate normalization of experimental data and also that up-regulatory effects of miRNAs are not uncommon in cells. We propose to establish this comprehensive method as standard for miRNA luciferase reporter assays to avoid errors and misinterpretations in the functionality of miRNAs.

  13. Enteritis cystica profunda: is trauma the etiology? Interval development in the previously normal ileum: a case report and literature review.

    Science.gov (United States)

    Chao, Jeffrey C; Lucha, Paul A

    2008-05-01

    Although well described in the colon, enteritis cystica profunda is an extremely rare lesion of the small intestine with only a few cases documented in English medical literature. It is a benign condition most often associated with Crohn's disease or Peutz-Jeghers syndrome in the adult. It has been described presenting as ileoileal intussusception in the pediatric population. We report a case of enteritis cystica profunda found incidentally on exploratory laparotomy with evidence of interval development over a 5-month period confirming trauma as the etiology.

  14. Flare-up of previously quiescent chronic osteomyelitis 20 years after childhood skeletal traction: a report of two cases.

    Science.gov (United States)

    Courvoisier, A; Grimaldi, M; Rubens-Duval, B; Chaussard, C; Saragaglia, D

    2011-12-01

    Management of lower limb fractures in children involves many approaches, spanning from conservative treatment to open reduction and internal fixation. A number of intermediate treatments have also been shown to be effective, notably skeletal traction. However, each of these techniques has its own advantages and disadvantages in terms of complications. In this report, we describe two new cases of chronic osteomyelitis that manifested (many years) after childhood skeletal traction. After analysing these two cases, we proposed measures that can be implemented to avoid such complications, along with a simple, appropriate, reproducible treatment approach. Copyright © 2011 Elsevier Masson SAS. All rights reserved.

  15. Primary hepatic lymphoma in a patient with previous rectal adenocarcinoma: a case report and discussion of etiopathogenesis and diagnostic tools.

    Science.gov (United States)

    Raimondo, Lucia; Ferrara, Idalucia; Stefano, Alfonso De; Cella, Chiara Alessandra; D'Armiento, Francesco Paolo; Ciancia, Giuseppe; Moretto, Roberto; Renzo, Amalia De; Carlomagno, Chiara

    2012-03-01

    Primary hepatic lymphoma is an extremely rare malignancy accounting for 0.016% of all cases of non-Hodgkin lymphomas. Approximately 1-4% of histologies described show a follicular pattern. We report a case of primary hepatic non-Hodgkin lymphoma that developed in a middle-aged woman 3 years after radical treatment (neoadjuvant chemoradiotherapy and surgery) for a rectal adenocarcinoma. Abdomen ultrasound showed a single nodule in the liver, which raised the issue of differential diagnosis with a metastasis from rectal cancer. After surgical removal of the nodule, histology revealed a primary B cell, stage IE follicular non-Hodgkin lymphoma, confined to the liver; indeed, no foci of lymphoma were found elsewhere in the body.

  16. Outcome of unicompartmental knee arthroplasty in octogenarians with tricompartmental osteoarthritis: A longer followup of previously published report

    Directory of Open Access Journals (Sweden)

    Sanjiv KS Marya

    2013-01-01

    Full Text Available Background: Unicompartmental knee arthroplasty (UKA has specific indications, producing excellent results. It, however, has a limited lifespan and needs eventual conversion to total knee arthroplasty (TKA. It is, therefore, a temporizing procedure in select active young patients with advanced unicompartmental osteoarthritis (UCOA. Being a less morbid procedure it is suggested as an alternative in the very elderly patients with tricompartmental osteoarthritis (TCOA. We performed UKA in a series of 45 octogenarians with TCOA predominant medial compartment osteoarthritis (MCOA and analyzed the results. Materials and Methods: Forty five octogenarian patients with TCOA predominant MCOA underwent UKA (19 bilateral from January 2002 to January 2012. All had similar preoperative work-up, surgical approach, procedure, implants and postoperative protocol. Clinicoradiological assessment was done at 3-monthly intervals for the first year, then yearly till the last followup (average 72 months, range 8-128 months. Results were evaluated using the knee society scores (KSS, satisfaction index [using the visual analogue scale (VAS] and orthogonal radiographs (for loosening, subsidence, lysis or implant wear. Resurgery for any cause was considered failure. Results: Four patients (six knees died due to medical conditions, two patients (three knees were lost to followup, and these were excluded from the final analysis. Barring two failures, all the remaining patients were pain-free and performing well at the final followup. Indications for resurgery were: medial femoral condyle fracture needing fixation subsequent conversion to TKA at 2 years (n=1 and progression of arthritis and pain leading to revision TKA at 6 years (n=1. Conclusion: UKA has shown successful outcomes with regards to pain relief and function with 96.4% implant survival and 94.9% good or excellent outcomes. Due to lower demands, early rehabilitation, less morbidity, and relative short life

  17. Robotic-Assisted Laparoscopic Treatment of Residual Ectopic Pregnancy in a Previous Cesarean Section Scar: A Case Report.

    Science.gov (United States)

    Schmitt, Andy; Crochet, Patrice; Agostini, Aubert

    To describe a technique of robotic-assisted laparoscopy of residual cesarean scar pregnancy (CSP) and uterine defect repair. Video case report, with step-by-step explanation of the procedure (Canadian Task Force classification III) SETTING: CSP may be treated by different approaches including surgery and methotrexate. Successful methotrexate treatments avoid an emergency surgical treatment. In these cases a residual CSP often remains and should be removed in women who desire to conceive. CSP is often associated with a cesarean section scar defect called an isthmocele. In case of isthmocele with important defect and desire for pregnancy, laparoscopic repair may be proposed. Diagnosis and treatment of isthmocele is usually performed in a second time after a successful treatment of CSP. In this case, a surgical treatment including the removal of the residual CSP and treatment of the isthmocele may be proposed. In this video we describe a technique for the surgical removal of residual CSP and isthmocele treatment by robotic-assisted laparoscopy. A 32-year-old patient developed a CSP treated by 2 in situ injections of methotrexate. A magnetic resonance imaging study performed 1 month after the last methotrexate injection revealed a persistent 4-cm residual CSP, associated with an isthmocele. Preoperative uterine artery embolization was performed to reduce intraoperative bleeding. After localization of the residual CSP on the left side, a temporary left uterine occlusion was performed. Residual CSP was totally removed. The residual defect and isthmocele were closed using delayed absorbable suture. Robotic-assisted laparoscopic removal of residual CSP and isthmocele treatment is a feasible and safe procedure. This procedure may be proposed in patients presenting with this condition after a methotrexate treatment of CSP. Copyright © 2016 AAGL. Published by Elsevier Inc. All rights reserved.

  18. Refuge narrative report 1972 : Kenai National Moose Range & Tuxedni National Wildlife Refuge

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This annual narrative report for Kenai National Moose Range and Tuxedni National Wildlife Refuge outlines Refuge accomplishments during the 1972 calendar year. The...

  19. Refuge narrative report 1970 : Kenai National Moose Range & Tuxedni National Wildlife Refuge

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This annual narrative report for Kenai National Moose Range and Tuxedni National Wildlife Refuge outlines Refuge accomplishments during the 1970 calendar year. The...

  20. Charles M. Russell National Wildlife Range : Narrative Report : January - December 1966

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This annual narrative report for Charles M. Russell National Wildlife Range (includes satellite refuges: Hailstone, Halfbreed, Mason, Miller, Yellow Water, War...

  1. Charles M. Russell National Wildlife Range : Narrative Report : January - December 1965

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This annual narrative report for Charles M. Russell National Wildlife Range (includes satellite refuges: Hailstone, Halfbreed, Mason, Miller, Yellow Water, War...

  2. Charles M. Russell National Wildlife Range : Narrative Report : January - December 1967

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This annual narrative report for Charles M. Russell National Wildlife Range (includes satellite refuges: Hailstone, Halfbreed, Mason, Miller, Yellow Water, War...

  3. Military Training: DOD Met Annual Reporting Requirements in Its 2016 Sustainable Ranges Report

    Science.gov (United States)

    2016-06-01

    from March 2016 to June 2016 in accordance with generally accepted government auditing standards . Those standards require that we plan and perform... internal , DOD factors and influences that constrain or have the potential to inhibit the full access or operational use of the live training and test...which the report met mandated statutory requirements and whether DOD faced challenges in preparing its report. We conducted this performance audit

  4. Post-Closure Inspection Report for the Tonopah Test Range, Nevada, For Calendar Year 2007

    Energy Technology Data Exchange (ETDEWEB)

    NSTec Environmental Restoration

    2008-06-01

    This report provides the results of the semiannual post-closure inspections conducted at the closed Corrective Action Unit (CAU) sites located on the Tonopah Test Range (TTR), Nevada. This report covers calendar year 2007 and includes inspection and repair activities completed at the following nine CAUs: (1) CAU 400: Bomblet Pit and Five Points Landfill (TTR); (2) CAU 404: Roller Coaster Lagoons and Trench (TTR); (3) CAU 407: Roller Coaster RadSafe Area (TTR); (4) CAU 423: Area 3 Underground Discharge Point, Building 0360 (TTR); (5) CAU 424: Area 3 Landfill Complexes (TTR); (6) CAU 426: Cactus Spring Waste Trenches (TTR); (7) CAU 427: Area 3 Septic Waste Systems 2, 6 (TTR); (8) CAU 453: Area 9 UXO Landfill (TTR); and (9) CAU 487: Thunderwell Site (TTR). In a letter from the Nevada Division of Environmental Protection (NDEP) dated December 5, 2006, NDEP concurred with the request to reduce the frequency of post-closure inspections of CAUs at TTR to an annual frequency. This letter is included in Attachment B. Post-closure inspections were conducted on May 15-16, 2007. All inspections were conducted according to the post-closure plans in the approved Closure Reports. The post-closure inspection plan for each CAU is included in Attachment B, with the exception of CAU 400. CAU 400 does not require post-closure inspections, but inspections of the vegetation and fencing are conducted as a best management practice. The inspection checklists for each site inspection are included in Attachment C, the field notes are included in Attachment D, and the site photographs are included in Attachment E. Vegetation monitoring of CAU 400, CAU 404, CAU 407, and CAU 426 was performed in May 2007, and the vegetation monitoring report is included in Attachment F. Maintenance and/or repairs were performed at CAU 453. Animal burrows observed during the annual inspection at CAU 453 were backfilled on August 1, 2007. At this time, the TTR post-closure site inspections should continue as

  5. Predictors of self-reported negative mood following a depressive mood induction procedure across previously depressed, currently anxious, and control individuals.

    Science.gov (United States)

    Scherrer, Martin C; Dobson, Keith S; Quigley, Leanne

    2014-09-01

    This study identified and examined a set of potential predictors of self-reported negative mood following a depressive mood induction procedure (MIP) in a sample of previously depressed, clinically anxious, and control participants. The examined predictor variables were selected on the basis of previous research and theories of depression, and included symptoms of depression and anxiety, negative and positive affect, negative and positive automatic thoughts, dysfunctional beliefs, rumination, self-concept, and occurrence and perceived unpleasantness of recent negative events. The sample consisted of 33 previously depressed, 22 currently anxious, and 26 non-clinical control participants, recruited from community sources. Participant group status was confirmed through structured diagnostic interviews. Participants completed the Velten negative self-statement MIP as well as self-report questionnaires of affective, cognitive, and psychosocial variables selected as potential predictors of mood change. Symptoms of anxiety were associated with increased self-reported negative mood shift following the MIP in previously depressed participants, but not clinically anxious or control participants. Increased occurrence of recent negative events was a marginally significant predictor of negative mood shift for the previously depressed participants only. None of the other examined variables was significant predictors of MIP response for any of the participant groups. These results identify factors that may increase susceptibility to negative mood states in previously depressed individuals, with implications for theory and prevention of relapse to depression. The findings also identify a number of affective, cognitive, and psychosocial variables that do not appear to influence mood change following a depressive MIP in previously depressed, currently anxious, and control individuals. Limitations of the study and directions for future research are discussed. Current anxiety

  6. Membranous (class V) renal disease in systemic lupus erythematosus may be more common than previously reported: results of a 6-year retrospective analysis.

    Science.gov (United States)

    Bhinder, Sumeet; Singh, Amrit; Majithia, Vikas

    2010-03-01

    The actual incidence and prevalence of the various histological classes (based on World Health Organization classification) of lupus nephritis (LN) are not known but seem to vary with sex, age, and ethnicity. We have analyzed renal biopsies in patients with systemic lupus erythematosus (SLE) at our center, and hereby report our experience. All renal biopsies performed at the University of Mississippi between January 1999 and December 2004 in patients with SLE were retrospectively analyzed. Results were validated by a detailed review of renal biopsy reports and additional records were reviewed for data specific to LN disease activity. There were 92 renal biopsies performed in patients with SLE during a 6-year period. These included 84 African Americans (72 women and 12 men), 5 whites (4 women and 1 man), and 3 unknown race (1 F, 2 M) subjects. The prevalence of LN classes in our cohort was as follows: class I (0%), class II (9.8%), class III (8.7%), class IV (36.9%), class V (40.2%), and class VI (4.3%). Prevalence of class V LN among males was high at 40%. In contrast to previous literature, isolated membranous lupus nephritis (MLN) was much more prevalent in this series-40% versus 14%. Also, no sex difference in the prevalence of MLN was seen. This biopsy cohort suggests that MLN/class V disease may be more common than previously reported especially in African American population.

  7. [Torsion of spermatic cord: can we trust a previous orchidopexy? A case report with loss of a single testis with medico-legal issue].

    Science.gov (United States)

    Van Glabeke, E; Ferhi, K; Maloum, C

    2010-10-01

    The authors report the case of a patient aged of 27 years who presented in the past a testicular torsion with loss of the ipsilateral testis and fixation of the contralateral one. Ten years later, he presented with pain on the remaining testis, which evolved to necrosis, and led to a second orchidectomy. In retrospective, it appears that the assumption that the testis had been adequately fixed ten years earlier led to the loss of the remaining testis. We thus recommend an urgent surgical exploration when facing a suspicion of spermatic cord torsion, regardless of previous history of orchidopexy. Copyright © 2010 Elsevier Masson SAS. All rights reserved.

  8. Lesser devil rays Mobula cf. hypostoma from Venezuela are almost twice their previously reported maximum size and may be a new sub-species.

    Science.gov (United States)

    Ehemann, N R; González-González, L V; Trites, A W

    2017-03-01

    Three rays opportunistically obtained near Margarita Island, Venezuela, were identified as lesser devil rays Mobula cf. hypostoma, but their disc widths were between 207 and 230 cm, which is almost double the reported maximum disc width of 120 cm for this species. These morphometric data suggest that lesser devil rays are either larger than previously recognized or that these specimens belong to an unknown sub-species of Mobula in the Caribbean Sea. Better data are needed to describe the distribution, phenotypic variation and population structure of this poorly known species. © 2017 The Fisheries Society of the British Isles.

  9. New Record of Sillago sinica (Pisces: Sillaginidae in Korean Waters, and Re-identification of Sillago parvisquamis Previously Reported from Korea as S. sinica

    Directory of Open Access Journals (Sweden)

    Seung Eun Bae

    2013-10-01

    Full Text Available A single specimen of the genus Sillago, collected from Gwangyang, Korea, in May 2009, is characterized by XI first dorsal fin spines, 3 or 4 rows of melanophore pattern along the second dorsal fin membrane, and a darkish posterior margin of the caudal fin. Our specimen was identified as Sillago sinica reported as a new species; this identification is confirmed by mitochondrial DNA cytochrome oxidase subunit I sequences, which show that our specimen corresponds to S. sinica (d=0.000 and differs from the congeneric species Sillago parvisquamis (d=0.170. Comparisons of Korean specimens previously reported as S. parvisquamis with specimens of S. sinica show that the S. parvisquamis specimens are actually S. sinica. We propose the new Korean name “buk-bang-jeom-bo-ri-myeol” for S. sinica.

  10. Orthogonal Range Reporting: Query Lower Bounds, Optimal Structures in 3-d, and Higher Dimensional Improvements

    DEFF Research Database (Denmark)

    Afshani, Peyman; Arge, Lars Allan; Larsen, Kasper Dalgaard

    2010-01-01

    , this is not the case in higher dimensions. In this paper we provide a space optimal pointer machine data structure for 3-d orthogonal range reporting that answers queries in O(log n + k) time. Thus we settle the complexity of the problem in 3-d. We use this result to obtain improved structures in higher dimensions...... data structure for the d-dimensional orthogonal range reporting problem in the pointer machine model of computation that uses S(n) space must spend Ω((log n/ log(S(n)/n))⌊d/2⌋--1) time to answer queries. Thus, if S(n)/n is poly-logarithmic, then the query time is at least Ω((log n/ log log n)⌊d/2......Orthogonal range reporting is the problem of storing a set of n points in d-dimensional space, such that the k points in an axis-orthogonal query box can be reported efficiently. While the 2-d version of the problem was completely characterized in the pointer machine model more than two decades ago...

  11. Prospective monitoring and self-report of previous falls among older women at high risk of falls and fractures: a study of comparison and agreement

    Science.gov (United States)

    Garcia, Patrícia A.; Dias, João M. D.; Silva, Silvia L. A.; Dias, Rosângela C.

    2015-01-01

    Background: The identification of the occurrence of falls is an important step for screening and for rehabilitation processes for the elderly. The methods of monitoring these events are susceptible to recording biases, and the choice of the most accurate method remains challenging. Objectives: (i) To investigate the agreement between retrospective self-reporting and prospective monitoring of methods of recording falls, and (ii) to compare the retrospective self-reporting of falls and the prospective monitoring of falls and recurrent falls over a 12-month period among older women at high risk of falls and fractures. Method: A total of 118 community-dwelling older women with low bone density were recruited. The incidence of falls was monitored prospectively in 116 older women (2 losses) via monthly phone calls over the course of a year. At the end of this monitoring period, the older women were asked about their recall of falls in the same 12-month period. The agreement between the two methods was analyzed, and the sensitivity and specificity of self-reported previous falls in relation to the prospective monitoring were calculated. Results: There was moderate agreement between the prospective monitoring and the retrospective self-reporting of falls in classifying fallers (Kappa=0.595) and recurrent fallers (Kappa=0.589). The limits of agreement were 0.35±1.66 falls. The self-reporting of prior falls had a 67.2% sensitivity and a 94.2% specificity in classifying fallers among older women and a 50% sensitivity and a 98.9% specificity in classifying recurrent fallers. Conclusion: Self-reporting of falls over a 12-month period underestimated 32.8% of falls and 50% of recurrent falls. The findings recommend caution if one is considering replacing monthly monitoring with annual retrospective questioning. PMID:26083603

  12. Prospective monitoring and self-report of previous falls among older women at high risk of falls and fractures: a study of comparison and agreement

    Directory of Open Access Journals (Sweden)

    Patrícia A. Garcia

    2015-06-01

    Full Text Available Background: The identification of the occurrence of falls is an important step for screening and for rehabilitation processes for the elderly. The methods of monitoring these events are susceptible to recording biases, and the choice of the most accurate method remains challenging. Objectives: (i To investigate the agreement between retrospective self-reporting and prospective monitoring of methods of recording falls, and (ii to compare the retrospective self-reporting of falls and the prospective monitoring of falls and recurrent falls over a 12-month period among older women at high risk of falls and fractures. Method: A total of 118 community-dwelling older women with low bone density were recruited. The incidence of falls was monitored prospectively in 116 older women (2 losses via monthly phone calls over the course of a year. At the end of this monitoring period, the older women were asked about their recall of falls in the same 12-month period. The agreement between the two methods was analyzed, and the sensitivity and specificity of self-reported previous falls in relation to the prospective monitoring were calculated. Results: There was moderate agreement between the prospective monitoring and the retrospective self-reporting of falls in classifying fallers (Kappa=0.595 and recurrent fallers (Kappa=0.589. The limits of agreement were 0.35±1.66 falls. The self-reporting of prior falls had a 67.2% sensitivity and a 94.2% specificity in classifying fallers among older women and a 50% sensitivity and a 98.9% specificity in classifying recurrent fallers. Conclusion: Self-reporting of falls over a 12-month period underestimated 32.8% of falls and 50% of recurrent falls. The findings recommend caution if one is considering replacing monthly monitoring with annual retrospective questioning.

  13. Prospective monitoring and self-report of previous falls among older women at high risk of falls and fractures: a study of comparison and agreement.

    Science.gov (United States)

    Garcia, Patrícia A; Dias, João M D; Silva, Silvia L A; Dias, Rosângela C

    2015-01-01

    The identification of the occurrence of falls is an important step for screening and for rehabilitation processes for the elderly. The methods of monitoring these events are susceptible to recording biases, and the choice of the most accurate method remains challenging. (i) To investigate the agreement between retrospective self-reporting and prospective monitoring of methods of recording falls, and (ii) to compare the retrospective self-reporting of falls and the prospective monitoring of falls and recurrent falls over a 12-month period among older women at high risk of falls and fractures. A total of 118 community-dwelling older women with low bone density were recruited. The incidence of falls was monitored prospectively in 116 older women (2 losses) via monthly phone calls over the course of a year. At the end of this monitoring period, the older women were asked about their recall of falls in the same 12-month period. The agreement between the two methods was analyzed, and the sensitivity and specificity of self-reported previous falls in relation to the prospective monitoring were calculated. There was moderate agreement between the prospective monitoring and the retrospective self-reporting of falls in classifying fallers (Kappa = 0.595) and recurrent fallers (Kappa = 0.589). The limits of agreement were 0.35 ± 1.66 falls. The self-reporting of prior falls had a 67.2% sensitivity and a 94.2% specificity in classifying fallers among older women and a 50% sensitivity and a 98.9% specificity in classifying recurrent fallers. Self-reporting of falls over a 12-month period underestimated 32.8% of falls and 50% of recurrent falls. The findings recommend caution if one is considering replacing monthly monitoring with annual retrospective questioning.

  14. Post-Closure Inspection Report for the Tonopah Test Range, Nevada, for Calendar Year 2012

    Energy Technology Data Exchange (ETDEWEB)

    NSTec Environmental Restoration

    2013-01-28

    This report provides the results of the annual post-closure inspections conducted at the closed Corrective Action Units (CAUs) located on the Tonopah Test Range (TTR), Nevada. This report covers calendar year 2012 and includes inspection and repair activities completed at the following CAUs: · CAU 400: Bomblet Pit and Five Points Landfill (TTR) · CAU 407: Roller Coaster RadSafe Area (TTR) · CAU 424: Area 3 Landfill Complexes (TTR) · CAU 453: Area 9 UXO Landfill (TTR) · CAU 487: Thunderwell Site (TTR)

  15. Post-Closure Inspection Report for the Tonopah Test Range, Nevada, For Calendar Year 2010

    Energy Technology Data Exchange (ETDEWEB)

    NSTec Environmental Restoration

    2011-03-30

    This report provides the results of the annual post-closure inspections conducted at the closed Corrective Action Units (CAUs) located on the Tonopah Test Range (TTR), Nevada. This report covers calendar year 2010 and includes inspection and repair activities completed at the following seven CAUs: · CAU 400: Bomblet Pit and Five Points Landfill (TTR) · CAU 407: Roller Coaster RadSafe Area (TTR) · CAU 424: Area 3 Landfill Complexes (TTR) · CAU 426: Cactus Spring Waste Trenches (TTR) · CAU 453: Area 9 UXO Landfill (TTR) · CAU 484: Surface Debris, Waste Sites, and Burn Area (TTR) · CAU 487: Thunderwell Site (TTR)

  16. Closure report for CAU No. 400: Bomblet Pit and Five Points Landfill, Tonopah test range

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-11-01

    This Closure Reports presents the information obtained from corrective and investigative actions performed to affirm the decision for clean closure of Corrective Action Unit No. 400 which includes the Bomblet Pit and the Five Points Landfill, two sites used for disposal of unexploded ordnance (UXO) and other solid waste at the U.S. Department of Energy`s (DOE) Tonopah Test Range, located in south-central Nevada. The first phase, or corrective action, for clean closure was performed under the Voluntary Correction Action Work Plan for Ordnance Removal from Five Disposal Sites at the Tonopah Test Range, hereafter referred to as the VCA Work Plan. The second phase consisted of collecting verification samples under the Streamlined Approach for Environmental Restoration Plan, CA U No. 400: Bomblet Pit and Five Points Landfill, Tonopah Test Range, hereafter referred to as the SAFER Plan. Results of the two phases are summarized in this document.

  17. 10-decade wide-range neutron-monitoring system. Final test report

    Energy Technology Data Exchange (ETDEWEB)

    Green, W.K.

    1970-10-01

    The objective of Project Agreement 49 was to design, fabricate, test, and evaluate under actual nuclear reactor operating conditions, one prototype counting-Campbelling wide-range type thermal neutron flux measurement channel. This report describes the basic system designed for PA 49, and describes and presents the results of tests conducted on the system. Individual module descriptions and schematics are contained in the instruction manual which was issued with the system.

  18. Three cases of donor-derived pulmonary tuberculosis in lung transplant recipients and review of 12 previously reported cases: opportunities for early diagnosis and prevention.

    Science.gov (United States)

    Mortensen, E; Hellinger, W; Keller, C; Cowan, L S; Shaw, T; Hwang, S; Pegues, D; Ahmedov, S; Salfinger, M; Bower, W A

    2014-02-01

    Solid organ transplant recipients have a higher frequency of tuberculosis (TB) than the general population, with mortality rates of approximately 30%. Although donor-derived TB is reported to account for tuberculosis infection is infrequently determined. We report 3 new cases of pulmonary TB in lung transplant recipients attributed to donor infection, and review the 12 previously reported cases to assess whether cases could have been prevented and whether any cases that might occur in the future could be detected and investigated more quickly. Specifically, we evaluate whether opportunities existed to determine TB risk on the basis of routine donor history, to expedite diagnosis through routine mycobacterial smears and cultures of respiratory specimens early post transplant, and to utilize molecular tools to investigate infection sources epidemiologically. On review, donor TB risk was present among 7 cases. Routine smears and cultures diagnosed 4 asymptomatic cases. Genotyping was used to support epidemiologic findings in 6 cases. Validated screening protocols, including microbiological testing and newer technologies (e.g., interferon-gamma release assays) to identify unrecognized M. tuberculosis infection in deceased donors, are warranted. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  19. Aqueous fullerene aggregates (nC60) generate minimal reactive oxygen species and are of low toxicity in fish: a revision of previous reports.

    Science.gov (United States)

    Henry, Theodore B; Petersen, Elijah J; Compton, Robert N

    2011-08-01

    This review aims to clarify inconsistencies in previous reports regarding the potential for aqueous aggregates of fullerenes (nC60) to generate reactive oxygen species (ROS) and cause toxicity in fish. Methods for evaluation of ROS production and toxicity of aqueous nC60 have evolved over time and limitations in initial studies have led to unintentional erroneous reports of nC60 ROS generation and toxicity. Some of these reports continue to lead to misconceptions of the environmental effects of C60. Critical review of the evidence (2007-2011) indicates that aqueous nC60 have minimal potential to produce ROS and that oxidative stress in fish is not induced by environmentally relevant exposure to nC60. Future studies should acknowledge that current evidence indicates low toxicity of nC60 and refrain from citing articles that attribute toxicity in fish to nC60 based on methods shown to be compromised by experimental artifacts. Despite low toxicity of nC60 in fish, an emerging environmental issue is that nC60 can affect environmental fate, transport, and bioavailability of co-contaminants in aquatic environments in a similar manner to that observed for other anthropogenic particulates (e.g., microplastics). Copyright © 2011 Elsevier Ltd. All rights reserved.

  20. Unexpected finding of T-cell lymphoma in a previously healthy 16-year-old patient after a thorax trauma: a case report

    DEFF Research Database (Denmark)

    Bach Okholm-Hansen, Anna; Brorson, Stig

    2014-01-01

    to describe lymphoma in relation to trauma.CASE PRESENTATION: A previously healthy 16-year-old Danish boy presented to our hospital with chest pain and accentuated protruding thoracic veins. Ten days prior to hospitalization he had suffered a blunt thoracic trauma while playing soccer. After drainage...... of an excessive amount of pleural fluid, he developed severe respiratory distress. A chest tube was inserted and he was transferred to a level 1 trauma centre. Here, a computed tomography scan unexpectedly revealed significantly swollen mediastinal and retroperitoneal lymph nodes, and he was later diagnosed...... with T-cell lymphoblastic lymphoma.CONCLUSIONS: This case emphasizes the importance of reacting to an unexplained large amount of pleural fluid after a patient suffers thoracic trauma and to consider possible underlying causes. This report is mainly addressed to emergency personnel, but it is also...

  1. Hepatocellular Carcinoma Metastasis to the Orbit in a Coinfected HIV+ HBV+ Patient Previously Treated with Orthotopic Liver Transplantation: A Case Report

    Directory of Open Access Journals (Sweden)

    S. Guerriero

    2011-01-01

    Full Text Available Hepatocellular carcinoma rarely metastasizes to the orbit. We report a 45-year-old male, HBV+, HIV+, with a past history of a liver transplant for ELSD (end-stage liver disease with hepatocellular carcinoma and recurrent HCC, who presented with proptosis and diplopia of the left eye. CT scans of the head revealed a large, irregular mass in the left orbit causing superior and lateral destruction of the orbital bone. Biopsy specimens of the orbital tumor showed features of metastatic foci of hepatocellular carcinoma. Only 16 other cases of HCC metastasis to the orbit have been described in literature, and this is the first case in a previously transplanted HIV+, HBV+ patient.

  2. Rj4, a Gene Controlling Nodulation Specificity in Soybeans, Encodes a Thaumatin-Like Protein But Not the One Previously Reported.

    Science.gov (United States)

    Tang, Fang; Yang, Shengming; Liu, Jinge; Zhu, Hongyan

    2016-01-01

    Rj4 is a dominant gene in soybeans (Glycine max) that restricts nodulation by many strains of Bradyrhizobium elkanii. The soybean-B. elkanii symbiosis has a low nitrogen-fixation efficiency, but B. elkanii strains are highly competitive for nodulation; thus, cultivars harboring an Rj4 allele are considered favorable. Cloning the Rj4 gene is the first step in understanding the molecular basis of Rj4-mediated nodulation restriction and facilitates the development of molecular tools for genetic improvement of nitrogen fixation in soybeans. We finely mapped the Rj4 locus within a small genomic region on soybean chromosome 1, and validated one of the candidate genes as Rj4 using both complementation tests and CRISPR/Cas9-based gene knockout experiments. We demonstrated that Rj4 encodes a thaumatin-like protein, for which a corresponding allele is not present in the surveyed rj4 genotypes, including the reference genome Williams 82. Our conclusion disagrees with the previous report that Rj4 is the Glyma.01G165800 gene (previously annotated as Glyma01g37060). Instead, we provide convincing evidence that Rj4 is Glyma.01g165800-D, a duplicated and unique version of Glyma.01g165800, that has evolved the ability to control symbiotic specificity. © 2016 American Society of Plant Biologists. All Rights Reserved.

  3. Prevalence of five previously reported and recurrent BRCA1 genetic rearrangement mutations in 20,000 patients from hereditary breast/ovarian cancer families.

    Science.gov (United States)

    Hendrickson, Brant C; Judkins, Thaddeus; Ward, Benjamin D; Eliason, Kristilyn; Deffenbaugh, Amie E; Burbidge, Lynn Anne; Pyne, Kristin; Leclair, Benoît; Ward, Brian E; Scholl, Thomas

    2005-07-01

    Many rearrangement mutations in the BRCA1 gene have been identified. It is becoming clear that some of these mutations are prevalent, and therefore their detection is necessary in order for clinical genetic tests to have high sensitivity. Published information on particular rearrangements is frequently limited to a single patient, small groups of patients, or patients of a particular ethnicity. The objectives of this work included characterizing the prevalence of five specific rearrangement mutations in a large North American patient population. A mutation-specific multiplex PCR assay was used for determining the prevalence of five BRCA1 rearrangement mutations that previously had been reported to occur in unrelated patients. The mutation status of these rearrangements, which came from 20,712 patients at high risk for hereditary breast and/or ovarian cancers who had submitted specimens for clinical genetic testing, is presented. The results, obtained from 2,634 mutation carriers, showed a 6-kb duplication of exon 13, identified in 53 patients (2.01%); a 26-kb deletion encompassing exons 14-20, detected in seven patients (0.27%); a 510-bp deletion of exon 22, detected in 5 patients (0.19%); and a 3.4-kb deletion of exon 13, detected in one patient (0.04%). A previously reported 7.1-kb deletion of exons 8-9 was not found. The high frequency of the exon 13 duplication makes it the fourth most prevalent mutation in these patients. These results provide an accurate picture of the prevalence of these mutations in hereditary breast/ovarian cancer patients undergoing genetic testing in North America. (c) 2005 Wiley-Liss, Inc.

  4. Temporary fusionless posterior occipitocervical fixation for a proximal junctional type II odontoid fracture after previous C2-pelvis fusion: case report, description of a new surgical technique, and review of the literature.

    Science.gov (United States)

    Theologis, Alexander A; Deviren, Vedat; Tay, Bobby

    2017-05-01

    Axial fractures in patients with a previous C2-pelvis posterior instrumented fusion are rare and may be challenging to manage. Motion preservation in the axial spine for these patients is important, as the C1-2 and Occipit-C1 joints are their only remaining mobile spinal segments. In this unique report, we present for the first time the use of a fusionless occipitocervical operation for the treatment of a type II odontoid fracture and unilateral C2 pars fracture adjacent to a previous C2-pelvis posterior instrumented fusion. Case report. Three years after proximal extension of a T3-pelvis posterior instrumented fusion to C2, the patient sustained a displaced odontoid fracture and unilateral C2 pars fracture after a mechanical fall. She underwent fracture stabilization with extension of instrumentation to the occiput. No attempt at fusion was performed. Post-operatively, she was distraught by severely limited neck range of motion, which was reflected in worsening of health-related quality of life (HRQoL) scores. The fracture healed uneventfully after which the instrumentation from the occiput and C1 were removed, which resulted in improvement of neck range of motion. Two years post-operatively, HRQoL scores showed minimal neck disability (NDI 12), no neck or arm pain (VAS 0), and outstanding general health (EQ-5D 85 out of 100, SF-36 PCS 35.3, SF-36 MCS 41.1). In this one patient, instrumentation without fusion allowed for successful and timely union of a displaced odontoid fracture in a patient with a previous C2-pelvis fusion. Axial range of motion was preserved after instrumentation removal.

  5. Incidence of and survival after subsequent cancers in carriers of pathogenic MMR variants with previous cancer: a report from the prospective Lynch syndrome database.

    Science.gov (United States)

    Møller, Pål; Seppälä, Toni; Bernstein, Inge; Holinski-Feder, Elke; Sala, Paola; Evans, D Gareth; Lindblom, Annika; Macrae, Finlay; Blanco, Ignacio; Sijmons, Rolf; Jeffries, Jacqueline; Vasen, Hans; Burn, John; Nakken, Sigve; Hovig, Eivind; Rødland, Einar Andreas; Tharmaratnam, Kukatharmini; de Vos Tot Nederveen Cappel, Wouter H; Hill, James; Wijnen, Juul; Jenkins, Mark; Green, Kate; Lalloo, Fiona; Sunde, Lone; Mints, Miriam; Bertario, Lucio; Pineda, Marta; Navarro, Matilde; Morak, Monika; Renkonen-Sinisalo, Laura; Frayling, Ian M; Plazzer, John-Paul; Pylvanainen, Kirsi; Genuardi, Maurizio; Mecklin, Jukka-Pekka; Möslein, Gabriela; Sampson, Julian R; Capella, Gabriel

    2017-09-01

    Today most patients with Lynch syndrome (LS) survive their first cancer. There is limited information on the incidences and outcome of subsequent cancers. The present study addresses three questions: (i) what is the cumulative incidence of a subsequent cancer; (ii) in which organs do subsequent cancers occur; and (iii) what is the survival following these cancers? Information was collated on prospectively organised surveillance and prospectively observed outcomes in patients with LS who had cancer prior to inclusion and analysed by age, gender and genetic variants. 1273 patients with LS from 10 countries were followed up for 7753 observation years. 318 patients (25.7%) developed 341 first subsequent cancers, including colorectal (n=147, 43%), upper GI, pancreas or bile duct (n=37, 11%) and urinary tract (n=32, 10%). The cumulative incidences for any subsequent cancer from age 40 to age 70 years were 73% for pathogenic MLH1 ( path_MLH1 ), 76% for path_MSH2 carriers and 52% for path_MSH6 carriers, and for colorectal cancer (CRC) the cumulative incidences were 46%, 48% and 23%, respectively. Crude survival after any subsequent cancer was 82% (95% CI 76% to 87%) and 10-year crude survival after CRC was 91% (95% CI 83% to 95%). Relative incidence of subsequent cancer compared with incidence of first cancer was slightly but insignificantly higher than cancer incidence in patients with LS without previous cancer (range 0.94-1.49). The favourable survival after subsequent cancers validated continued follow-up to prevent death from cancer. The interactive website http://lscarisk.org was expanded to calculate the risks by gender, genetic variant and age for subsequent cancer for any patient with LS with previous cancer. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  6. Refracture of osteoporotic vertebral body concurrent with cement fragmentation at the previously treated vertebral level after balloon kyphoplasty: a case report.

    Science.gov (United States)

    Li, Xigong; Lou, Xianfeng; Lin, Xiangjin; Du, Junhua

    2014-05-01

    Kyphoplasty has been shown to provide symptomatic relief of vertebral compression fractures refractory to medical therapy. However, few reports have focused on refracture of cemented vertebrae after kyphoplasty. The presence of cemented vertebrae refracture concurrent with cement fragmentation is an extremely rare condition. We reported an 86-year-old man with a T12 osteoporotic compression fracture undergoing the kyphoplasty treatment. The patient postoperatively continued to have back pain at the same level. The solid lumped polymethylmethacrylate (PMMA) mass and inadequate use and insufficient filling of PMMA cement were observed in postoperative radiographs and magnetic resonance image (MRI) examination. He refused to receive the surgical intervention, but had not strict compliance with oral anti-osteoporotic medications. Ten months postoperatively, refracture of osteoporotic vertebral body concurrent with cement fragmentation occurred at the previously kyphoplasty-treated vertebral level. Bone mineral analysis showed severe osteoporosis with a T-score of -4.0. The patient finally obtained therapeutic benefit of pain relief and bony union of T12 vertebral body by consistently adhering to anti-osteoporotic medication treatment. This case illustrated that patients who underwent kyphoplasty to treat osteoporotic vertebral compression fractures with intravertebral fracture should be strictly followed up and supervised in their anti-osteoporotic medication treatment. The interdigitation injection pattern of PMMA and sufficient PMMA filling with trabeculae in the kyphoplasty procedure also might prevent refracture of the cemented vertebrae concurrent with PMMA fragmentation.

  7. Summary Report on the SAE 2016 Range Extenders for Electric Vehicles Symposium

    Energy Technology Data Exchange (ETDEWEB)

    Curran, Scott [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Wagner, Robert M. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Campbell, Russ [SRA International, Inc., Arlington, VA (United States)

    2017-03-01

    The SAE 2016 Range Extenders for Electric Vehicles Symposium was a 2-day technical meeting focused on the role of advanced internal combustion engines (ICEs) and other novel energy converter technologies for extending the range of electric vehicles (EVs). The first-of-its-kind symposium was notable for focusing solely on the range extender (REx) technologies and not the EVs. The technical program featured presentations from international leaders from industry, government, national laboratories, and academia. The opening keynote presentations covered a broad range of topics including consumer behavior, policy implications, regulatory considerations, and REx architectures as enablers for advanced technologies. The technical sessions focused on an array of REx technologies including conventional ICEs, as well as less conventional or emerging technologies such as microturbines, fuel cells, low-temperature combustion engines, and aluminum-air batteries. The symposium included two panel sessions. The trend toward increasing vehicle electrification and the changing role of ICEs and other auxiliary power unit technologies for use as REx’s is leading to new research and design development needs. The symposium captured the interest of the industry and research communities in exploring the opportunities and challenges associated with REx’s for EVs. This report includes key takeaways, summarized below, and draft notes for each presentation and panel discussion.

  8. Femoroacetabular impingement and its implications on range of motion: a case report

    Directory of Open Access Journals (Sweden)

    Bloem Rolf M

    2011-04-01

    Full Text Available Abstract Introduction Femoroacetabular impingement leads to limited hip motion, pain and progressive damage to the labrum. Assessment of the amount and location of excessive ossification can be difficult, and removal does not always lead to pain relief and an increase of function. One of the challenges ahead is to discover why certain cases have poor outcomes. Case presentation The technical and clinical results of two consecutive arthroscopic shavings of an osseous cam protrusion are described in our patient, a 50-year-old Caucasian man with complaints of femoroacetabular impingement. At 12 weeks after the first arthroscopic shaving, our patient still experienced pain. Using a range of motion simulation system based on computed tomography images the kinematics of his hip joint were analyzed. Bone that limited range of motion was removed in a second arthroscopic procedure. At six months post-operatively our patient is almost pain free and has regained a range of motion to a functional level. Conclusion This case demonstrates the relevance of range of motion simulation when the outcome of primary arthroscopic management is unsatisfactory. Such simulations may aid clinicians in determining the gain of a second operation. This claim is supported by the correlation of the simulations with clinical outcome, as shown in this case report.

  9. Post-Closure Inspection Report for the Tonopah Test Range, Nevada, For Calendar Year 2008

    Energy Technology Data Exchange (ETDEWEB)

    NSTec Environmental Restoration

    2009-03-19

    This report provides the results of the annual post-closure inspections conducted at the closed Corrective Action Unit (CAU) sites located on the Tonopah Test Range (TTR), Nevada. This report covers calendar year 2008 and includes inspection and repair activities completed at the following ten CAUs: CAU 400: Bomblet Pit and Five Points Landfill (TTR) CAU 404: Roller Coaster Lagoons and Trench (TTR) CAU 407: Roller Coaster RadSafe Area (TTR) CAU 423: Area 3 Underground Discharge Point, Building 0360 (TTR) CAU 424: Area 3 Landfill Complexes (TTR) CAU 426: Cactus Spring Waste Trenches (TTR) CAU 427: Area 3 Septic Waste Systems 2, 6 (TTR) CAU 453: Area 9 UXO Landfill (TTR) CAU 484: Surface Debris, Waste Sites, and Burn Area (TTR) CAU 487: Thunderwell Site (TTR)

  10. The Value of Motion: Patient-Reported Outcome Measures Are Correlated With Range of Motion in Total Ankle Replacement.

    Science.gov (United States)

    Dekker, Travis J; Hamid, Kamran S; Federer, Andrew E; Steele, John R; Easley, Mark E; Nunley, James A; Adams, Samuel B

    2017-12-01

    The proposed benefit of total ankle replacement (TAR) over ankle fusion is preserved ankle motion, thus we hypothesized that an increase in range of motion (ROM) is positively correlated with validated patient-reported outcome measures (PROMs) in individuals receiving TAR. Patients undergoing TAR at a single academic medical center between 2007 and 2013 were evaluated in this study. In addition to a minimum of 2-year follow-up, complete preoperative and postoperative outcome measures for the Foot and Ankle Disability Index (FADI), Short Musculoskeletal Function Assessment (SMFA) Bother and Function Indices, Visual Analog Scale (VAS), and 36-Item Short Form Health Survey (SF-36) were requisite for inclusion. Standardized weightbearing maximum dorsiflexion and plantarflexion sagittal radiographs were obtained and previously described ankle and foot measurements were performed to determine ankle ROM. Eighty-eight patients met inclusion criteria (33 INBONE, 18 Salto-Talaris, 37 STAR). Mean time to final ROM radiographs was 43.8 months (range 24-89 months). All aforementioned PROMs improved between preoperative evaluation and most recent follow-up (  P dorsiflexion was positively associated with FADI, SF-36 MCS, and SMFA Function (  P motion was positively correlated with multiple PROMs. Disease-specific and generic health-related quality of life PROMs demonstrated improvement postoperatively in all domains when evaluating final total range of motion. Patients who undergo TAR for end-stage osteoarthritis with improvement in ROM demonstrate a direct correlation with improved patient-centric metrics and outcome scores. Level III: Retrospective comparative study.

  11. Post-Closure Inspection Report for the Tonopah Test Range, Nevada, for Calendar Year 2014

    Energy Technology Data Exchange (ETDEWEB)

    Silvas, A. J. [National Security Technologies, LLC, Las Vegas, NV (United States). Nevada Test Site; Lantow, Tiffany A. [National Security Technologies, LLC, Las Vegas, NV (United States). Nevada Test Site

    2015-03-25

    This report provides the results of the annual post-closure inspections conducted at the closed Corrective Action Units (CAUs) located on the Tonopah Test Range (TTR), Nevada. This report covers calendar year 2014 and includes inspection and repair activities completed at the following CAUs; CAU 400: Bomblet Pit and Five Points Landfill (TTR); CAU 407: Roller Coaster RadSafe Area (TTR); CAU 424: Area 3 Landfill Complexes (TTR); CAU 453: Area 9 UXO Landfill (TTR); and CAU 487: Thunderwell Site (TTR) Inspections were conducted according to the post-closure plans in the approved Closure Reports and subsequent correspondence with the Nevada Division of Environmental Protection. The post-closure inspection plans and subsequent correspondence modifying the requirements for each CAU are included in Appendix B. The inspection checklists are included in Appendix C. Photographs taken during inspections are included in Appendix D. The annual post-closure inspections were conducted on May 28, 2014. Maintenance was required at CAU 407. Animal burrows were backfilled and erosion repairs were performed. Vegetation monitoring was performed at CAU 407 in June 2014. The vegetation monitoring report is included in Appendix E.

  12. "Preliminary data suggest rates of male military sexual trauma may be higher than previously reported": Retraction of Sheppard et al. (2015).

    Science.gov (United States)

    2016-02-01

    Reports the retraction of "Preliminary data suggest rates of male military sexual trauma may be higher than previously reported" by Sean C. Sheppard, Edward J. Hickling, Mitch Earleywine, Tim Hoyt, Amanda R. Russo, Matthew R. Donati and Kevin E. Kip (Psychological Services, 2015[Nov], Vol 12[4], 344-347). The following article from the November 2015 issue is being retracted. The retraction is at the request of the authors. The data analysis was flawed due to the method used to test for statistical significance which was not consistent with modern methods. This compromised the study findings. Thus, the conclusions about statistical significance drawn in the paper were not consistent with the data. The statistical testing error that occurred was unintentional and acknowledged by the authors when pointed out by external scholars. All authors of the article joined in the request for the retraction. (The following abstract of the original article appeared in record 2015-49326-002.) Stigma associated with disclosing military sexual trauma (MST) makes estimating an accurate base rate difficult. Anonymous assessment may help alleviate stigma. Although anonymous research has found higher rates of male MST, no study has evaluated whether providing anonymity sufficiently mitigates the impact of stigma on accurate reporting. This study used the unmatched count technique (UCT), a form of randomized response techniques, to gain information about the accuracy of base rate estimates of male MST derived via anonymous assessment of Operation Enduring Freedom (OEF)/Operation Iraqi Freedom (OIF) combat veterans. A cross-sectional convenience sample of 180 OEF/OIF male combat veterans, recruited via online websites for military populations, provided data about history of MST via traditional anonymous self-report and the UCT. The UCT revealed a rate of male MST more than 15 times higher than the rate derived via traditional anonymous assessment (1.1% vs. 17.2%). These data suggest that

  13. Case report of right hamate hook fracture in a patient with previous fracture history of left hamate hook: is it hamate bipartite?

    Directory of Open Access Journals (Sweden)

    Norton Sandra

    2006-10-01

    Full Text Available Abstract Background Hamate hook fracture is a common fracture in golfers and others who play sports that involve rackets or sticks such as tennis or hockey. This patient had a previous hamate fracture in the opposing wrist along with potential features of hamate bipartite. Case presentation A 19 year old male presented with a complaint of right wrist pain on the ulnar side of the wrist with no apparent mechanism of injury. The pain came on gradually one week before being seen in the office and he reported no prior care for the complaint. His history includes traumatic left hamate hook fracture with surgical excision. Conclusion The patient was found to have marked tenderness over the hamate and with a prior fracture to the other wrist, computed tomography of the wrist was ordered revealing a fracture to the hamate hook in the right wrist. He was referred for surgical evaluation and the hook of the hamate was excised. Post-surgically, the patient was able to return to normal activity within eight weeks. This case is indicative of fracture rather than hamate bipartite. This fracture should be considered in a case of ulnar sided wrist pain where marked tenderness is noted over the hamate, especially after participation in club or racket sports.

  14. Hybrids between Pseudoplatystoma corruscans and P. reticulatum (Siluriformes: Pimelodidae previously reported in the Upper Paraná River are likely escapes from aquaculture farms: evidence from microsatellite markers

    Directory of Open Access Journals (Sweden)

    Rafael A. Baggio

    2016-01-01

    Full Text Available ABSTRACT The production of hybrids of the 'pintado', Pseudoplatystoma corruscans (Spix & Agassiz, 1829 and 'cachara', Pseudoplatystoma reticulatum (Eigenmann & Eigenmann, 1889 in captivity has generated many concerns about the possibility of introduction of farmed hybrids into natural environments. In the last decade, hybrids between these species, known as 'pintachara' or 'cachapinta', were reported from different regions of the Upper Paraná River basin. Prospection of these hybrids is important in order to orient conservation programs for the species involved. Knowledge of the presence of these hybrids will direct conservation strategies towards prevention and/or mitigation of the effects of cross breeding in natural populations of P. corruscans (the native species of the genus and farmed hybrids. In this study, surveyed the larval population using molecular tools to detect the presence and assess the origin (natural hybridization or escapes from fish farms of hybrids in natural water bodies. Nine microsatellite markers were used to detect signals of hybridization and introgression of P. reticulatum in larvae and adults of P. corruscans in Upper Paraná River basin, between Itaipu Dam and Porto Primavera Dam. The specimens were sampled in the Upper Paraná channel and in tributaries where hybrids had been detected in the past, during two reproductive seasons. Despite of that, no sign of hybridization and introgression was found in the 171 larvae and 75 adults sampled, suggesting that the specimens detected in previous studies had originated from escapes of aquaculture farms.

  15. Update of the pompe disease mutation database with 60 novel GAA sequence variants and additional studies on the functional effect of 34 previously reported variants.

    Science.gov (United States)

    Kroos, Marian; Hoogeveen-Westerveld, Marianne; Michelakakis, Helen; Pomponio, Robert; Van der Ploeg, Ans; Halley, Dicky; Reuser, Arnold

    2012-08-01

    Pompe disease is an autosomal recessive lysosomal glycogen storage disorder, characterized by progressive muscle weakness. Deficiency of acid α-glucosidase (EC; 3.2.1.20/3) can be caused by numerous pathogenic variants in the GAA gene. The Pompe Disease Mutation Database at http://www.pompecenter.nl aims to list all variants and their effect. This update reports on 94 variants. We examined 35 novel and 34 known mutations by site-directed mutagenesis and transient expression in COS-7 cells or HEK293T cells. Each of these mutations was given a severity rating using a previously published system, based on the level of acid α-glucosidase activity in medium and transfected cells and on the quantity and quality of the different molecular mass species in the posttranslational modification and transport of acid α-glucosidase. This approach enabled to classify 55 missense mutations as pathogenic and 13 as likely nonpathogenic. Based on their nature and the use of in silico analysis (Alamut® software), 12 of the additional 25 novel mutations were predicted to be pathogenic including 4 splicing mutations, 6 mutations leading to frameshift, and 2 point mutations causing stop codons. Seven of the additional mutations were considered nonpathogenic (4 silent and 3 occurring in intron regions), and 6 are still under investigation. © 2012 Wiley Periodicals, Inc.

  16. Post-Closure Inspection Report for the Tonopah Test Range, Nevada, for Calendar Year 2013

    Energy Technology Data Exchange (ETDEWEB)

    Silvas, A. J.

    2014-03-03

    This report provides the results of the annual post-closure inspections conducted at the closed Corrective Action Units (CAUs) located on the Tonopah Test Range (TTR), Nevada. This report covers calendar year 2013 and includes inspection and repair activities completed at the following CAUs: • CAU 400: Bomblet Pit and Five Points Landfill (TTR) • CAU 407: Roller Coaster RadSafe Area (TTR) • CAU 424: Area 3 Landfill Complexes (TTR) • CAU 453: Area 9 UXO Landfill (TTR) • CAU 487: Thunderwell Site (TTR) Inspections were conducted according to the post-closure plans in the approved Closure Reports and subsequent correspondence with the Nevada Division of Environmental Protection. The post-closure inspection plans and subsequent correspondence modifying the requirements for each CAU are included in Appendix B. The inspection checklists are included in Appendix C. Field notes are included in Appendix D. Photographs taken during inspections are included in Appendix E. The annual post-closure inspections were conducted on May 14, 2013. Maintenance was performed at CAU 400, CAU 424, and CAU 453. At CAU 400, animal burrows were backfilled. At CAU 424, erosion repairs were completed at Landfill Cell A3-3, subsidence was repaired at Landfill Cell A3-4, and additional lava rock was placed in high-traffic areas to mark the locations of the surface grade monuments at Landfill Cell A3-3 and Landfill Cell A3-8. At CAU 453, two areas of subsidence were repaired and animal burrows were backfilled. Vegetation monitoring was performed at the CAU 400 Five Points Landfill and CAU 407 in June 2013. The vegetation monitoring report is included in Appendix F.

  17. Post-Closure Inspection Report for the Tonopah Test Range, Nevada, For Calendar Year 2011

    Energy Technology Data Exchange (ETDEWEB)

    NSTec Environmental Restoration

    2012-02-21

    This report provides the results of the annual post-closure inspections conducted at the closed Corrective Action Units (CAUs) located on the Tonopah Test Range (TTR), Nevada. This report covers calendar year 2011 and includes inspection and repair activities completed at the following CAUs: (1) CAU 400: Bomblet Pit and Five Points Landfill (TTR); (2) CAU 407: Roller Coaster RadSafe Area (TTR); (3) CAU 424: Area 3 Landfill Complexes (TTR); (4) CAU 453: Area 9 UXO Landfill (TTR); and (5) CAU 487: Thunderwell Site (TTR) Inspections were conducted according to the post-closure plans in the approved Closure Reports. The post-closure inspection plan for each CAU is included in Appendix B. The inspection checklists are included in Appendix C, field notes are included in Appendix D, and photographs taken during inspections are included in Appendix E. The annual post-closure inspections were conducted May 3 and 4, 2011. Maintenance was performed at CAU 424, CAU 453, and CAU 487. At CAU 424, two surface grade monuments at Landfill Cell A3-3 could not be located during the inspection. The two monuments were located and marked with lava rock on July 13, 2011. At CAU 453, there was evidence of animal burrowing. Animal burrows were backfilled on July 13, 2011. At CAU 487, one use restriction warning sign was missing, and wording was faded on the remaining signs. A large animal burrow was also present. The signs were replaced, and the animal burrow was backfilled on July 12, 2011. As a best management practice, the use restriction warning signs at CAU 407 were replaced with standard Federal Facility Agreement and Consent Order signs on July 13, 2011. Vegetation monitoring was performed at the CAU 400 Five Points Landfill and CAU 407 in June 2011, and the vegetation monitoring report is included in Appendix F.

  18. Preliminary report of transfrontier disease surveillance in free-ranging buffalo in the Caprivi Strip, Namibia

    Directory of Open Access Journals (Sweden)

    Massimo Scacchia

    2010-09-01

    Full Text Available A capture operation to ascertain the health status of free-ranging buffalo (Syncerus caffer from six areas in the Caprivi Strip in the north-east corner of Namibia is described. In-depth reports on buffalo capture operations and their cost, with detailed descriptions of diseases for research purposes, sampling techniques, field processing of samples and laboratory-related costs are still lacking in the literature. This paper describes materials, methods and the related costs of a disease surveillance operation conducted among buffalo in Namibia. The survey attempted to provide information designed to improve the control of infectious diseases in the Caprivi Strip, a key area bordering Angola, Zambia, Botswana and Zimbabwe.

  19. Hellsgate Big Game Winter Range Wildlife Mitigation Project : Annual Report 2008.

    Energy Technology Data Exchange (ETDEWEB)

    Whitney, Richard P.; Berger, Matthew T.; Rushing, Samuel; Peone, Cory

    2009-01-01

    The Hellsgate Big Game Winter Range Wildlife Mitigation Project (Hellsgate Project) was proposed by the Confederated Tribes of the Colville Reservation (CTCR) as partial mitigation for hydropower's share of the wildlife losses resulting from Chief Joseph and Grand Coulee Dams. At present, the Hellsgate Project protects and manages 57,418 acres (approximately 90 miles2) for the biological requirements of managed wildlife species; most are located on or near the Columbia River (Lake Rufus Woods and Lake Roosevelt) and surrounded by Tribal land. To date we have acquired about 34,597 habitat units (HUs) towards a total 35,819 HUs lost from original inundation due to hydropower development. In addition to the remaining 1,237 HUs left unmitigated, 600 HUs from the Washington Department of Fish and Wildlife that were traded to the Colville Tribes and 10 secure nesting islands are also yet to be mitigated. This annual report for 2008 describes the management activities of the Hellsgate Big Game Winter Range Wildlife Mitigation Project (Hellsgate Project) during the past year.

  20. Calendar Year 2004 annual site environmental report : Tonopah Test Range, Nevada & Kauai Test Facility, Hawaii.

    Energy Technology Data Exchange (ETDEWEB)

    Montoya, Amber L.; Wagner, Katrina; Goering, Teresa Lynn; Koss, Susan I.; Salinas, Stephanie A.

    2005-09-01

    Tonopah Test Range (TTR) in Nevada and Kauai Test Facility (KTF) in Hawaii are government-owned, contractor-operated facilities operated by Sandia Corporation, a subsidiary of Lockheed Martin Corporation. The U.S. Department of Energy (DOE), National Nuclear Security Administration (NNSA), through the Sandia Site Office (SSO), in Albuquerque, NM, manages TTR and KTF's operations. Sandia Corporation conducts operations at TTR in support of DOE/NNSA's Weapons Ordnance Program and has operated the site since 1957. Westinghouse Government Services subcontracts to Sandia Corporation in administering most of the environmental programs at TTR. Sandia Corporation operates KTF as a rocket preparation launching and tracking facility. This Annual Site Environmental Report (ASER) summarizes data and the compliance status of the environmental protection and monitoring program at TTR and KTF through Calendar Year (CY) 2004. The compliance status of environmental regulations applicable at these sites include state and federal regulations governing air emissions, wastewater effluent, waste management, terrestrial surveillance, and Environmental Restoration (ER) cleanup activities. Sandia Corporation is responsible only for those environmental program activities related to its operations. The DOE/NNSA, Nevada Site Office (NSO) retains responsibility for the cleanup and management of ER TTR sites. Currently, there are no ER Sites at KTF. Environmental monitoring and surveillance programs are required by DOE Order 450.1, Environmental Protection Program (DOE 2005) and DOE Order 231.1A, Environment, Safety, and Health Reporting (DOE 2004b).

  1. Long-range Weather Prediction and Prevention of Climate Catastrophes: A Status Report

    Science.gov (United States)

    Caldeira, K.; Caravan, G.; Govindasamy, B.; Grossman, A.; Hyde, R.; Ishikawa, M.; Ledebuhr, A.; Leith, C.; Molenkamp, C.; Teller, E.; Wood, L.

    1999-08-18

    As the human population of Earth continues to expand and to demand an ever-higher quality-of-life, requirements for ever-greater knowledge--and then control--of the future of the state of the terrestrial biosphere grow apace. Convenience of living--and, indeed, reliability of life itself--become ever more highly ''tuned'' to the future physical condition of the biosphere being knowable and not markedly different than the present one. Two years ago, we reported at a quantitative albeit conceptual level on technical ways-and-means of forestalling large-scale changes in the present climate, employing practical means of modulating insolation and/or the Earth's mean albedo. Last year, we reported on early work aimed at developing means for creating detailed, high-fidelity, all-Earth weather forecasts of two weeks duration, exploiting recent and anticipated advances in extremely high-performance digital computing and in atmosphere-observing Earth satellites bearing high-technology instrumentation. This year, we report on recent progress in both of these areas of endeavor. Preventing the commencement of large-scale changes in the current climate presently appears to be a considerably more interesting prospect than initially realized, as modest insolation reductions are model-predicted to offset the anticipated impacts of ''global warming'' surprisingly precisely, in both space and time. Also, continued study has not revealed any fundamental difficulties in any of the means proposed for insolation modulation and, indeed, applicability of some of these techniques to other planets in the inner Solar system seems promising. Implementation of the high-fidelity, long-range weather-forecasting capability presently appears substantially easier with respect to required populations of Earth satellites and atmospheric transponders and data-processing systems, and more complicated with respect to transponder lifetimes in the actual atmosphere; overall, the enterprise seems more

  2. Post-Closure Inspection Report for the Tonopah Test Range, Nevada, for Calendar Year 2009

    Energy Technology Data Exchange (ETDEWEB)

    NSTec Environmental Restoration

    2010-05-28

    This report provides the results of the annual post-closure inspections conducted at the closed Corrective Action Unit (CAU) sites located on the Tonopah Test Range (TTR), Nevada. This report covers calendar year 2009 and includes inspection and repair activities completed at the following seven CAUs: · CAU 400: Bomblet Pit and Five Points Landfill (TTR) · CAU 407: Roller Coaster RadSafe Area (TTR) · CAU 424: Area 3 Landfill Complexes (TTR) · CAU 426: Cactus Spring Waste Trenches (TTR) · CAU 453: Area 9 UXO Landfill (TTR) · CAU 484: Surface Debris, Waste Sites, and Burn Area (TTR) · CAU 487: Thunderwell Site (TTR) The annual post-closure inspections were conducted May 5–6, 2009. All inspections were conducted according to the post-closure plans in the approved Closure Reports. The post-closure inspection plan for each CAU is included in Attachment B, with the exception of CAU 400. CAU 400 does not require post-closure inspections, but inspections of the vegetation and fencing are conducted as a best management practice. The inspection checklists for each site inspection are included in Attachment C, the field notes are included in Attachment D, and the site photographs are included in Attachment E. Vegetation monitoring of CAU 400, CAU 404, CAU 407, and CAU 426 was performed in June 2009, and the vegetation monitoring report is included in Attachment F. Maintenance was performed at CAU 453. Animal burrows observed during the annual inspection were backfilled, and a depression was restored to grade on June 25, 2009. Post-closure site inspections should continue as scheduled. Vegetation survey inspections have been conducted annually at CAUs 400, 404, 407, and 426. Discontinuation of vegetation surveys is recommended at the CAU 400 Bomblet Pit and CAU 426, which have been successfully revegetated. Discontinuation of vegetation surveys is also recommended at CAU 404, which has been changed to an administrative closure with no inspections required. Vegetation

  3. Johnson Space Center's Free Range Bicycle Program.- Fall 2015 Intern Report

    Science.gov (United States)

    Lee-Stockton, Willem

    2015-01-01

    NASA's Johnson Space Center is a big place, encompassing 1,620 acres and more than a hundred buildings. Furthermore, there are reportedly 15 thousand employees, all of which have somewhere to be. To facilitate the movement of all these people JSC has historically relied on human power. Pedaling their way towards deep space, bicycles have been the go to method. Currently there are about 200 Free Range Bicycles at JSC. Free Range Bicycles belong to nobody, except NASA, and are available for anybody to use. They are not to be locked or hidden (although frequently are) and the intention is that there will always be a bike to hop on to get where you're going (although it may not be the bike you rode in on). Although not without its own shortcomings, the Free Range Bicycle Program has continued to provide low cost, simple transportation for NASA's JSC. In addition to the approximately 200 Free Range Bicycles, various larger divisions (like engineering) will often buy a few dozen bikes for their team members to use or individuals will bring their own personal bike to either commute or use on site. When these bicycles fall into disrepair or are abandoned (from retirees etc) they become a problem at JSC. They are an eye sore, create a safety hazard and make it harder to find a working bike in a time of need. The Free Range Program hopes to address this first problem by "tagging out" abandoned or out of service bicycles. A bright orange "DO NOT OPERATE" tag is placed on the bike and given a serial number for tracking purposes. See picture to the right. If the bike has an active owner with intentions to repair the bike the bottom of the tag has instructions for how to claim the abandoned bicycle. After being tagged the owner of the bicycle has 30 days to claim the bicycle and either haul it off site or get it repaired (and labeled) in accordance with Johnson's Bicycle Policy. If the abandoned bicycle is not claimed within 30 days it becomes the property of the Government. The

  4. Closure Report for Corrective Action Unit 426: Cactus Spring Waste Trenches, Tonopah Test Range, Nevada

    Energy Technology Data Exchange (ETDEWEB)

    Dave Madsen

    1998-08-01

    This Closure Report provides the documentation for closure of the Cactus Spring Waste Trenches Corrective Action Unit (CAU) 426. The site is located on the Tonopah Test Range, approximately 225 kilometers northwest of Las Vegas, NV. CAU 426 consists of one corrective action site (CAS) which is comprised of four waste trenches. The trenches were excavated to receive solid waste generated in support of Operation Roller Coaster, primary the Double Tracks Test in 1963, and were subsequently backfilled. The Double Tracks Test involved use of live animals to assess the biological hazards associated with the nonnuclear detonation of plutonium-bearing devices. The Nevada Division of Environmental Protection approved Corrective Action Plan (CAP)which proposed ''capping'' methodology. The closure activities were completed in accordance with the approved CAP and consisted of constructing an engineered cover in the area of the trenches, constructing/planting a vegetative cover, installing a perimeter fence and signs, implementing restrictions on future use, and preparing a Post-Closure Monitoring Plan.

  5. Hellsgate Winter Range Mitigation Project; Long-term Management Plan, Project Report 1993, Final Draft.

    Energy Technology Data Exchange (ETDEWEB)

    Berger, Matthew T.

    1994-01-01

    A study was conducted on the Hellsgate Winter Range Mitigation Project area, a 4,943 acre ranch purchased for mitigating some habitat losses associated with the original construction of Grand Coulee Dam and innundation of habitat by Lake Roosevelt. A Habitat Evaluation Procedure (HEP) study was used to determine habitat quality and quantity baseline data and future projections. Target species used in the study were sharp-tailed grouse (Tympanuchus phasianellus), mule deer (Odocoileus hemoinus), mink (Mustela vison), spotted sandpiper (Actiius colchicus), bobcat (Felis reufs), blue grouse (Dendragapus obscurus), and mourning dove (Zenaida macroura). From field data collected, limiting life values or HSI's (Habitat Suitability Index's) for each indicator species was determined for existing habitats on project lands. From this data a long term management plan was developed. This report is designed to provide guidance for the management of project lands in relation to the habitat cover types discussed and the indicator species used to evaluate these cover types. In addition, the plan discusses management actions, habitat enhancements, and tools that will be used to enhance, protect and restore habitats to desired conditions. Through planned management actions biodiversity and vegetative structure can be optimized over time to reduce or eliminate, limiting HSI values for selected wildlife on project lands.

  6. Closure Report for Corrective Action Unit 499: Hydrocarbon Spill Site, Tonopah Test Range, Nevada

    Energy Technology Data Exchange (ETDEWEB)

    K. B. Campbell

    2002-07-01

    This Closure Report (CR) has been prepared for Corrective Action Unit (CAU) 499: Hydrocarbon Spill Site, in accordance with the Federal Facility Agreement and Consent Order (FFACO, 1996) and the Nevada Division of Environmental Protection (NDEP)-approved Streamlined Approach for Environmental Restoration (SAFER) Plan for CAU 499: Hydrocarbon Spill Site, Tonopah Test Range (TTR), Nevada (US Department of Energy, Nevada Operations Office [DOE/NV], 2001). CAU 499 consists of one Corrective Action Site (CAS): RG-25-001-RD24: Radar 24 Diesel Spill Site which is approximately 4.0 kilometers (2.5 miles) southwest of the Area 3 Compound at the end of Avenue 24. The Hydrocarbon Spill Site is a diesel fuel release site that is assumed to have been caused by numerous small historical over-fillings, spills, and leaks from an above-ground storage tank (AST) over a period of approximately 36 years. The tank was located on the east side of Building 24-50 on the TTR.

  7. STEREOTACTIC RADIOTHERAPY FOR SPINAL INTRADURAL METASTASES DEVELOPING WITHIN OR ADJACENT TO THE PREVIOUS IRRADIATION FIELD – REPORT OF THREE CASES –

    Science.gov (United States)

    MORI, YOSHIMASA; HASHIZUME, CHISA; SHIBAMOTO, YUTA; KOBAYASHI, TATSUYA; NAKAZAWA, HISATO; HAGIWARA, MASAHIRO; TSUGAWA, TAKAHIKO

    2013-01-01

    ABSTRACT Results of stereotactic radiotherapy (SRT) for spinal intradural metastases developing inside or adjacent to the previous external-beam radiation therapy (EBRT) field are shown in 3 cases. One case of spinal intramedullary metastasis and two cases of intradural extramedullary metastases were treated using a Novalis shaped-beam SRT.  Case 1 developed an intramedullary metastatic tumor in the C1 spinal medulla inside the previous whole brain EBRT field and another lesion adjacent to the field in the C2 spinal medulla. Case 2 developed intradural extramedullary metastasis around C6-8 inside the previous EBRT field for the primary lung adenocarcinoma. Case 3 developed multiple spinal intradural extramedullary metastatic deposits after surgical resection and following whole brain EBRT for brain metastasis. We delivered 24 to 36 Gy in 5 to 12 fractions. The treated tumors were stable or decreased in size until the patients’ death from the primary cancer (10, 22, and 5 months). Neurological symptoms were stable or improved in all 3 patients. Palliative SRT using Novalis is expected to be safe and effective even if the patient develops spinal intradural metastases within or adjacent to the previous irradiation field. PMID:24640183

  8. Alkali Burn of the Ocular Surface Associated With a Commonly Used Antifog Agent for Eyewear: Two Cases and a Review of Previous Reports.

    Science.gov (United States)

    Welling, John D; Pike, Evan C; Mauger, Thomas F

    2016-02-01

    To report 2 cases of ocular chemical burns associated with the use of a swim goggle antifog agent and to review the literature for this and similar antifog products. Case reports and systematic review of the medical literature, material safety data, product safety reports, and consumer reviews. Two males, one 46 years and the other 41 years, were referred to our clinic with chemical burns of the ocular surface after using the same goggle antifog agent while swimming in a triathlon. Both sustained significant epithelial defects. Fortunately, with prompt treatment, both of our patients returned to their baseline vision within a few weeks without suffering sight-threatening complications. These are the first cases of ocular chemical burn secondary to use of an eyewear antifog agent to be reported in the medical literature. Similar reports found in consumer forums suggest that our cases are not isolated and these products may have the potential to cause vision-threatening chemical burns.

  9. National semen analysis reference range reporting: adherence to the 1999 World Health Organization guidelines 10 years later.

    Science.gov (United States)

    Penn, Heidi A; Windsperger, Andrew; Smith, Zachary; Parekattil, Sijo J; Kuang, Wayne W; Kolettis, Peter N; Nangia, Ajay K

    2011-06-01

    To determine the adherence by laboratories across the United States to the standard semen analysis guidelines and parameter reference ranges 10 years after being set by the World Health Organization (WHO) in 1999 and to compare compliance between regional laboratories vs. specialty assisted reproductive technology (ART) laboratories. Observational study. Regional clinical and reproductive endocrinology andrology laboratories. Blank or deidentified semen analysis reports were collected from laboratories through direct contact or from reports received as part of clinical care for male infertility. Adherence to semen analysis reference range reporting as recommended by the 1999 WHO guidelines. Semen analyses reports were collected from 111 laboratories from 31 different states. Of 111 laboratories, 26 (23%) reported all reference range parameters in accordance with the guidelines. Of 65 ART laboratories, 21 (32%) complied with all reference range parameters as outlined by the guidelines, vs. 5 of 46 non-ART laboratories (11%). Seventy percent of laboratories that did not report 1999 WHO parameters did so because of differences in reference values for normal morphology. Adherence to WHO 1999 semen analysis reference range guidelines has not been achieved by ART and non-ART laboratories 10 years after being introduced. Non-ART laboratories report reference ranges less accurately than ART laboratories. Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  10. Lack of in vitro constitutive activity for four previously reported TSH receptor mutations identified in patients with nonautoimmune hyperthyroidism and hot thyroid carcinomas

    OpenAIRE

    Paschke, Ralf; Jaeschke, Holger; Mueller, Sandra; Eszlinger, Markus

    2010-01-01

    Abstract Objective: Constitutively activating mutations of the TSHR are the major cause for nonautoimmune hyperthyroidism. Re-examination of constitutive activity previously determined in CHO cell lines recently demonstrated the caveats for the in vitro determination of constitutive TSHR activity, which leads to false positive conclusions regarding the molecular origin of hyperthyroidism or hot thyroid carcinomas. Design: Mutations L677V and T620I identified in hot thyroid carc...

  11. Quarterly report on wild life and activities appurtenant thereto, from July 1, 1936 to September 30, 1936: [National Bison Range

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This narrative report summarizes conditions on the National Bison Range between July and September, 1936. Wildlife, birds, grazing, fire prevention, improvement and...

  12. Narrative report FY 1977 for Charles M. Russell National Wildlife Range and Hailstone, Halfbreed, Lake Mason & War Horse Wildlife Refuges

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This narrative report for Charles M. Russell National Wildlife Range (including the satellite refuges) outlines Refuge accomplishments during the 1977 calendar year....

  13. Closure Report for Corrective Action Unit 412: Clean Slate I Plutonium Dispersion (TTR) Tonopah Test Range, Nevada, Revision 0

    Energy Technology Data Exchange (ETDEWEB)

    Matthews, Patrick [Navarro, Las Vegas, NV (United States)

    2016-08-22

    This Closure Report (CR) presents information supporting the clean closure of Corrective Action Unit (CAU) 412: Clean Slate I Plutonium Dispersion (TTR), located on the Tonopah Test Range, Nevada. CAU 412 consists of a release of radionuclides to the surrounding soil from a storage–transportation test conducted on May 25, 1963. Corrective action investigation (CAI) activities were performed in April and May 2015, as set forth in the Streamlined Approach for Environmental Restoration (SAFER) Plan for Corrective Action Unit 412: Clean Slate I Plutonium Dispersion (TTR), Tonopah Test Range, Nevada; and in accordance with the Soils Activity Quality Assurance Plan. The purpose of the CAI was to fulfill data needs as defined during the data quality objectives process. The CAU 412 dataset of investigation results was evaluated based on a data quality assessment. This assessment demonstrated the dataset is complete and acceptable for use in fulfilling the data needs identified by the data quality objectives process. This CR provides documentation and justification for the clean closure of CAU 412 under the FFACO without further corrective action. This justification is based on historical knowledge of the site, previous site investigations, implementation of the 1997 interim corrective action, and the results of the CAI. The corrective action of clean closure was confirmed as appropriate for closure of CAU 412 based on achievement of the following closure objectives: Radiological contamination at the site is less than the final action level using the ground troops exposure scenario (i.e., the radiological dose is less than the final action level): Removable alpha contamination is less than the high contamination area criterion: No potential source material is present at the site, and any impacted soil associated with potential source material has been removed so that remaining soil contains contaminants at concentrations less than the final action levels: and There is

  14. Fort Peck Game Range: Refuge narrative report: May, June, July, August 1952

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This narrative report for Fort Peck NWR and the easement refuges outlines Refuge accomplishments from May through August of 1952. The report begins by summarizing...

  15. Refuge narrative report : January - April 1963 : Aleutian Islands National Wildlife Refuge and Izembek National Wildlife Range

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This narrative report for Aleutian Islands and Izembek NWRs outlines Refuge accomplishments from January through April of 1963. The report begins by summarizing the...

  16. Refuge Narrative Report : January-April 1952 : Kenai National Moose Range

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This narrative report for Kenai National Wildlife Refuge summarizes refuge activities from January through April of 1952. The report begins with general information...

  17. Refuge Narrative Report : September-December 1950 : Kenai National Moose Range

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This narrative report for Kenai National Wildlife Refuge summarizes refuge activities from September through December of 1950. The report begins with general...

  18. Clarence Rhode National Wildlife Range : Annual Narrative Report : Calendar Year 1976

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This narrative report for Clarence Rhode National Wildlife Refuge outlines Refuge accomplishments during the 1976 calendar year. The report begins with an...

  19. Refuge Narrative Report : September-December 1963 : Kenai National Moose Range

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This narrative report for Kenai National Wildlife Refuge summarizes refuge activities from September through December of 1963. The report begins with general...

  20. Clarence Rhode National Wildlife Range : Annual Narrative Report : Calendar Year 1977

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This narrative report for Clarence Rhode National Wildlife Refuge outlines Refuge accomplishments during the 1977 calendar year. The report begins with an...

  1. Fort Peck Game Range: Refuge narrative report: September, October, November, December 1952

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This narrative report for Fort Peck NWR and the easement refuges outlines Refuge accomplishments from September through December of 1952. The report begins by...

  2. Refuge Narrative Report : May-August 1950 : Kenai National Moose Range

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This narrative report for Kenai National Wildlife Refuge summarizes refuge activities from May through August of 1950. The report begins with general information...

  3. Fort Peck Game Range: Refuge narrative report: January, February, March, April 1951

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This narrative report for Fort Peck NWR and the easement refuges outlines Refuge accomplishments from January through April of 1951. The report begins by summarizing...

  4. Narrative report of Aleutian Islands National Wildlife Refuge and Izembek National Wildlife Range : April - August, 1961

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This narrative report for Aleutian Islands and Izembek NWRs outlines Refuge accomplishments from May through August of 1961. The report begins by summarizing the...

  5. The coming revolution in particle physics: Report of the Fermilab Long Range Planning Committee

    Energy Technology Data Exchange (ETDEWEB)

    Jeff Appel et al.

    2004-06-22

    In early 2003, the Fermilab Director formed a committee (Appendix A) to examine options for the long-range future of Fermilab. Specifically, the committee was asked to respond to a charge (Appendix B), which laid out the assumptions, which were to underlie our discussions. The committee met a few times during the spring of 2003 and formulated a plan of action. It identified a number of issues that deserved attention, and a subcommittee was formed to focus on each. We agreed that in addressing these key issues, a broader participation was appropriate. The manner in which that was achieved varied from subcommittee to subcommittee to group. In some cases the expanded membership participated in all the discussions, in others, particular presentations were solicited and heard. Some subgroups met regularly over several months, others convened only for a small number of discussions. We have attempted to list participants in Appendix C. General presentations indicating the purpose of the work were given, for example at the Fermilab Users Annual Meeting. Towards the end of the summer some sense of direction developed and a series of open meetings was organized by the different subgroups. These meetings of two and more hour's duration gave the broader laboratory and user community a further chance to react to perceived directions and to make their opinions known. They were extremely well attended. In all, nearly 100 people have participated in the process including the development of initial drafts and proto-recommendations. A larger number attended the various open sessions. It is therefore likely, even expected, that the general thrusts of this report are no surprise. Nevertheless, the committee met in a number of plenary closed sessions including a two-day retreat in which all the issues were discussed and a common view was developed. The Director and Deputy Director heard and interacted with the discussions in most of these meetings. In attempting to converge, we

  6. Report of findings: Contaminant study of the environment surrounding the Cape Romanzof Long Range Radar Site

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The Cape Romanzof Long Range Radar Site (Cape Romanzof) contains many petroleum-related spills and hazardous substances. Therefore, in 1987 and 1988 a field study...

  7. Waterfowl population and habitat study, Kenai National Moose Range, Kenai, Alaska: Special report

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — During the period between May 27 and August 28, 1961, a waterfowl population and habitat study was conducted on the Kenai National Moose Range by personnel of the...

  8. Geothermal potential of the Cascade Mountain Range: exploration and development. Special report No. 10

    Energy Technology Data Exchange (ETDEWEB)

    1981-05-01

    Eighteen papers are included, one of which was previously abstracted for EDB. A separate abstract was prepared for each of the remaining seventeen papers for Energy Research Abstracts (ERA); ten of the papers are included in Energy Abstracts for Policy Analysis (EPA).

  9. The usefulness of chelation therapy for the remission of symptoms caused by previous treatment with mercury-containing pharmaceuticals: a case report

    OpenAIRE

    Corsello, Serafina; Fulgenzi,Alessandro; Vietti, Daniele; Ferrero, Maria Elena

    2009-01-01

    Introduction A great deal of data regarding the toxicology of mercury has been recently reported. Although the most common human exposures to mercury are currently mercury vapour from amalgam tooth fillings, methylmercury from seafood and ethylmercury as a preservative in vaccines, in the past mercury compounds have been used in the treatment of syphilis. Case presentation Mercury intoxication was found in a 67 year-old Italian man affected by neurological symptoms of apparently unknown origi...

  10. Field report: Exploring the Doonerak fenster of the central Brooks Range, Alaska, USA

    Directory of Open Access Journals (Sweden)

    Justin V. Strauss

    2017-07-01

    Full Text Available Arctic Alaska is a ‘suspect’ terrane that encompasses approximately 20% of Alaska, stretching from the southern Brooks Range all the way to the continental shelves of the Chukchi and Beaufort Seas. Although the origin and subsequent travels of this large crustal fragment are debated among geologists, most researchers agree upon its composite nature and exotic origin. To constrain the early geological history of this terrane, we describe a recent expedition to the Doonerak fenster of the central Brooks Range. This area has long been regarded as a key locality for understanding the structural evolution of the Mesozoic–Cenozoic Brooks Range orogen; however, our target was different: a unique sequence of volcanic and siliciclastic rocks (Apoon assemblage exposed beneath a profound pre-Mississippian unconformity, which we argue is of key importance to understanding the early Paleozoic tectonic history of northern Alaska and the greater Arctic.

  11. Four Forensic Entomology Case Studies: Records and Behavioral Observations on Seldom Reported Cadaver Fauna With Notes on Relevant Previous Occurrences and Ecology.

    Science.gov (United States)

    Lindgren, Natalie K; Sisson, Melissa S; Archambeault, Alan D; Rahlwes, Brent C; Willett, James R; Bucheli, Sibyl R

    2015-03-01

    A yearlong survey of insect taxa associated with human decomposition was conducted at the Southeast Texas Applied Forensic Science (STAFS) facility located in the Center for Biological Field Studies of Sam Houston State University in Huntsville, TX. During this study, four insect-cadaver interactions were observed that represent previously poorly documented yet forensically significant interactions: Syrphidae maggots colonized a corpse in an aquatic situation; Psychodidae adults mated and oviposited on an algal film that was present on a corpse that had been recently removed from water; several Panorpidae were the first insects to feed upon a freshly placed corpse in the autumn; and a noctuid caterpillar was found chewing and ingesting dried human skin. Baseline knowledge of insect-cadaver interactions is the foundation of forensic entomology, and unique observations have the potential to expand our understanding of decomposition ecology. © The Author 2015. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  12. Cri du chat syndrome and congenital heart disease: a review of previously reported cases and presentation of an additional 21 cases from the Pediatric Cardiac Care Consortium.

    Science.gov (United States)

    Hills, Christine; Moller, James H; Finkelstein, Marsha; Lohr, Jamie; Schimmenti, Lisa

    2006-05-01

    To analyze the cases submitted to the Pediatric Cardiac Care Consortium (PCCC) database from 1982 to 2002 to determine the frequency and distribution of congenital heart disease (CHD) found in this population, to review the literature for previously published accounts of CHD in this population, and to review current genotype-phenotype associations for cri du chat (CDC) syndrome with CHD. We performed a retrospective review of the 98422 CHD cases submitted to the PCCC between 1982 and 2002, to find patients who had a noncardiac diagnosis of CDC syndrome. A total of 21 patients (15 female and 6 male patients) were identified. Although some patients had multiple cardiac anomalies, they were categorized according to primary diagnoses on the basis of the most hemodynamically significant component. The patient groups were ventricular septal defect (n = 6), patent ductus arteriosus (n = 6), tetralogy of Fallot (n = 5), pulmonary valve atresia with ventricular septal defect (n = 2), pulmonary valve stenosis (n = 1), and double-outlet right ventricle (n = 1). Eighteen of the 21 patients underwent surgical repair of their defects. There was 1 late operative death. To determine whether the observed frequency of these cardiac defects among patients with CDC syndrome was comparable to that of the general population of patients with CHD, data for all cases submitted to the PCCC from 1982 to 2002 were used. Use of these numbers to determine expected frequencies for these defects showed significantly greater proportions of patients with these specific lesions among the patients with CDC syndrome. Currently there is no clear understanding of the genomic cause of the prevalence of these defects in the population with CDC syndrome, although CHD has been noted among patients with other deletion syndromes.

  13. Feline leprosy due to Candidatus 'Mycobacterium lepraefelis': Further clinical and molecular characterisation of eight previously reported cases and an additional 30 cases.

    Science.gov (United States)

    O'Brien, Carolyn R; Malik, Richard; Globan, Maria; Reppas, George; McCowan, Christina; Fyfe, Janet A

    2017-09-01

    This paper, the last in a series of three on 'feline leprosy', provides a detailed description of disease referable to the previously unnamed species, Candidatus 'Mycobacterium lepraefelis', a close relative of the human pathogens Mycobacterium leprae and Mycobacterium lepromatosis. Cases were sourced retrospectively and prospectively for this observational study, describing clinical, geographical and molecular microbiological data for cats definitively diagnosed with Candidatus 'M lepraefelis' infection. A total of 145 cases of feline leprosy were scrutinised; 114 'new' cases were sourced from the Victorian Infectious Diseases Reference Laboratory (VIDRL) records, veterinary pathology laboratories or veterinarians, and 31 cases were derived from six published studies. Thirty-eight cats were definitively diagnosed with Candidatus 'M lepraefelis' infection. Typically, cats tended to be middle-aged or older when first infected, with a male predilection. Affected cats typically had widespread cutaneous lesions, in some cases after initially localised disease. Advanced cases were often systemically unwell. All cats had outdoor access. The histological picture was lepromatous in the majority of patients, although two cases had tuberculoid disease. In one case that underwent necropsy, lesions were evident in the liver, spleen and lungs. Treatment was varied, although most cats received a combination of oral clarithromycin and rifampicin. Prognosis for recovery was variable, but typically poor. Candidatus 'M lepraefelis' typically causes high bacterial index (lepromatous) feline leprosy that in some cases progresses to systemic mycobacteriosis. The disease has a variable clinical course and prognosis. Many cases either died or were euthanased due to the infection. Multilocus sequence analysis reveals a heterogeneous picture and further analysis of draft genome sequencing may give clues to the taxonomy and epidemiology of this organism. Prospective treatment trials and

  14. Charles M. Russell National Wildlife Range : Narrative Report : January - December 1964

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This annual narrative report for Charles M. Russell NWR (including the satellite refuges: Hailstone, Halfbreed, Mason, Miller, Yellow Water, War Horse, and Wild...

  15. Atypical femoral fracture in a beta-thalassemia major patient with previous bisphosphonate use: case report and a review of the literature.

    Science.gov (United States)

    Lampropoulou-Adamidou, K; Tournis, S; Triantafyllopoulos, I K

    2016-03-01

    There are numerous studies presenting the beneficial effect of bisphosphonates (BPs) on bone disease of patients suffering from beta-thalassemia major (TM). Although BPs have been widely used, adverse events have been described including atypical femoral fractures (AFF). In the present case, a male adult patient suffering from TM sustained an AFF fulfilling all major and two minor criteria. Before AFF, the patient had been treated with zoledronic acid for three years and remained another one year without osteoporosis therapy. To our knowledge, this is the first reported case of AFF in a patient suffering from TM, probably due to the small sample size of patients with thalassemia. The purpose of the present case is to increase the awareness amongst haematologists, who mainly deal with TM patients, of the adverse events of BP use.

  16. Natural History of Asymptomatic and Unrepaired Vascular Rings: Is Watchful Waiting a Viable Option? A New Case and Review of Previously Reported Cases.

    Science.gov (United States)

    Loomba, Rohit S

    2016-12-21

    Vascular rings are a rare form of congenital heart disease in which abnormal aortic arch anatomy leads to encircling of the esophagus and/or trachea by the aortic vasculature. Symptoms can develop from this and prompt the need for surgery. A natural history study has been done on mildly symptomatic patients but no such study has been done on asymptomatic patients. We present a case report of three children with asymptomatic vascular rings who continue to receive follow-up without intervention and review all published cases of asymptomatic or unrepaired vascular rings. Clinical observation of asymptomatic and mildly symptomatic vascular rings, regardless of aortic arch anatomy, seems to be a safe approach. Children with mild symptoms almost invariably seem to have resolution of their symptoms by four years of age.

  17. Radiation port cutaneous metastases: Reports of two patients whose recurrent visceral cancers presented as skin lesions at the site of previous radiation and literature review

    Directory of Open Access Journals (Sweden)

    Brian Spencer Hoyt

    2014-01-01

    Full Text Available Radiation therapy is associated with a variety of complications, including the development of primary skin cancers in the radiated region. However, it is rare for patients with visceral cancers who are treated with radiation therapy to subsequently develop cutaneous metastasis within the radiation port. We describe two patients with internal malignancies who developed cutaneous metastases within their radiation ports following radiotherapy. In addition, we used PubMed to perform an extensive literature review and identify additional reports of cutaneous metastasis within a radiation port. We excluded patients who developed melanoma or primary skin cancers in the radiation port. We also excluded patients with non-solid organ malignancies. Herein, we summarize the characteristics of 23 additional patients who experienced radiation port cutaneous metastases and explore possible mechanisms for the occurrence of radiation port cutaneous metastases.

  18. A miniature powerplant for very small, very long range autonomous aircraft. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Tad McGeer

    1999-09-29

    The authors have developed a new piston engine offering unprecedented efficiency for a new generation of miniature robotic aircraft. Following Phase 1 preliminary design in 1996--97, they have gone forward in Phase 2 to complete detail design, and are nearing completion of a first batch of ten engines. A small-engine dynamometer facility has been built in preparation for the test program. Provisions have been included for supercharging, which will allow operation at ceilings in the 10,000 m range. Component tests and detailed analysis indicate that the engine will achieve brake-specific fuel consumption well below 300 gm/kWh at power levels of several hundred watts. This level of performance opens the door to development of tabletop-sized aircraft having transpacific range and multi-day endurance, which will offer extraordinary new capabilities for meteorology, geomagnetic, and a variety of applications in environmental monitoring and military operations.

  19. Distribution and Fate of Energetics on DoD Test and Training Ranges: Interim Report 5

    Science.gov (United States)

    2005-04-01

    Military Reservation (MMR) near Falmouth, MA (USA) on Cape Cod . The Training Ranges and Impact Area at Camp Edwards encompass approximately 14,000...were fired until 1997, when a moratorium on artillery and mortar firing was established by the U.S. Environmental Protection Agency (EPA). A compre...Sagamore Lens, a major groundwater recharge 102 Chapter 6 Update on Massachusetts Military Reservation area and the most productive portion of the Cape Cod

  20. Semiannual Status Report. [excitation of electromagnetic waves in the whistler frequency range

    Science.gov (United States)

    1994-01-01

    During the last six months, we have continued our study of the excitation of electromagnetic waves in the whistler frequency range and the role that these waves will play in the acceleration of electrons and ions in the auroral region. A paper entitled 'Electron Beam Excitation of Upstream Waves in the Whistler Mode Frequency Range' was listed in the Journal of Geophysical Research. In this paper, we have shown that an anisotropic electron beam (or gyrating electron beam) is capable of generating both left-hand and right-hand polarized electromagnetic waves in the whistler frequency range. Since right-hand polarized electromagnetic waves can interact with background electrons and left-hand polarized waves can interact with background ions through cyclotron resonance, it is possible that these beam generated left-hand and right-hand polarized electromagnetic waves can accelerate either ions or electrons (or both), depending on the physical parameters under consideration. We are currently carrying out a comprehensive study of the electromagnetic whistler and lower hybrid like waves observed in the auroral zone using both wave and particle data. Our first task is to identify these wave modes and compare it with particle observations. Using both the DE-1 particle and wave measurements, we can positively identify those electromagnetics lower hybrid like waves as fast magnetosonic waves and the upper cutoff of these waves is the local lower hybrid frequency. From the upper cutoff of the frequency spectrum, one can infer the particle density and the result is in very good agreement with the particle data. Since these electromagnetic lower hybrid like waves can have frequencies extended down to the local ion cyclotron frequency, it practically confirms that they are not whistler waves.

  1. Gouty tophi caused limited knee range of motion: a case report.

    Science.gov (United States)

    Kijkunasathian, Chusak; Woratanarat, Patarawan; Saengpetch, Nadhaporn

    2009-12-01

    Gout is a disease of purine metabolism characterized by monosodium urate crystal deposition. Gouty tophi can mimic many conditions such as infection or neoplasm. We descriptively presented a case of a 29-year-old male with gouty toph. Data was obtained from patient chart. This patient presented with limited knee joint range of motion after sport injury. Arthroscopic examination was performed in order to confirm the diagnosis of the meniscal injury. The result showed the synovium with white toothpaste-like chalky urate crystals in the joint cartilage. An atypical presentation of gouty tophi can sometime mislead to diagnose an internal derangement of the knee.

  2. Report on the lunar ranging at McDonald Observatory. [spark gap configuration and photomultiplier system

    Science.gov (United States)

    Silverberg, E. C.

    1977-01-01

    Range measurements to an accuracy of 5 cm were achieved following improvements in the laser oscillator configuration and the photomultiplier system. Modifications to the laser include a redesigned pockel cell mount to eliminate stressing of the cell crystal; an improved electrically triggered spark gap for sharpening the electrical pulse; the use of a brewster plate in the cavity to eliminate pre-pulsing; improved alignment for the oscillator system; and increased cavity lifetime through thin film polarizer technology. Laser calibration data are presented along with the lunar laser operations log for June to October 1977.

  3. Installation restoration program, remedial investigation/feasibility study report addendum for Indian Mountain Long Range Radar Station, Alaska. Final report, 1 August-18 December 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-01-01

    The following report is an addendum to the Indian Mountain Long Range Radar Station (LRRS) Remedial Investigation/Feasibility Study (RI/FS) report dated October 1995 (Air Force 1995a). This report and the activities described were undertaken to fulfill the goals and objectives of the Air Force Installation Restoration Program (IRP). This report includes findings from additional characterization activities conducted in August 1995 at five of 11 Indian Mountain IRP source areas and revisions to RI/FS report conclusions for those source areas.

  4. Evaluation of geothermal potential of the basin and range province of New Mexico. Technical report

    Energy Technology Data Exchange (ETDEWEB)

    Landis, G.P.; Callender, J.F.; Elston, W.E.; Jiracek, G.R.; Kudo, A.M.; Woodward, L.A.; Swanberg, C.A.

    1976-06-01

    This continuing research is designed to provide an integrated geological, geophysical, and geochemical study of the geothermal energy potential of promising thermal anomalies in the Rio Grande rift, Basin and Range province, the Mogollon--Datil volcanic field of New Mexico. Specific objectives undertaken in this study include the following: (a) reconnaissance and detailed geologic mapping (Animas Valley, Radium Springs, Alum Mountain, Truth or Consequences, Ojo Caliente, Albuquerque---Belene basin, and San Ysidro); (b) geochemical studies including reconnaissance water sampling (Animas Valley, Radium Springs and Alum Mountain); and (c) geophysical surveys using deep electric-resistivity, gravity, and magnetic techniques (Radium Springs, Animas Valley and Truth or Consequences). The results of one and one-half summer field seasons and approximately two years of analytical work, laboratory research, and development of research equipment and facilities are covered. Publications, communications, and public service resulting from the first years of U.S.G.S. and State funding are listed in Appendix A.

  5. Nephrotic-range proteinuria in an eight-year-old traveler with severe dengue: Case report and review of the literature.

    Science.gov (United States)

    Hebbal, Pooja; Darwich, Yamil; Fong, Jane; Hagmann, Stefan H F; Purswani, Murli U

    2016-01-01

    We report a case of an eight-year-old male, native of the Dominican Republic, who visited the U.S. and was admitted to a pediatric intensive care unit with severe dengue. He needed aggressive fluid management for dengue shock syndrome and developed proteinuria on the sixth day of his illness, shortly after his nadir thrombocytopenia. His proteinuria peaked on the eight day, and reduced to trace levels by the tenth day of his illness, coinciding with normalization of his platelet count. His highest random urine protein/creatinine ratio was in the nephrotic range, at 3.9 g/g. Dengue fever can cause a wide spectrum of acute kidney injury (AKI), ranging in incidence from 0.9 to 36%. Review of the literature shows that nephrotic-range proteinuria is an uncommon complication of AKI caused by dengue, reported thus far only in Southeast Asia. Immune-mediated mechanisms may explain the observed association between dengue-induced thrombocytopenia and severe proteinuria, in this case, and previously reported cases. Dengue virus infection is the commonest mosquito-borne disease in the world with substantial morbidity and mortality. Well-designed prospective studies are needed to further characterize the extent and mechanisms of AKI in populations living in countries with ongoing transmission, as well as in those with travel-associated disease. Copyright © 2016 Elsevier Ltd. All rights reserved.

  6. Varying the item format improved the range of measurement in patient-reported outcome measures assessing physical function

    DEFF Research Database (Denmark)

    Liegl, Gregor; Gandek, Barbara; Fischer, H. Felix

    2017-01-01

    Background: Physical function (PF) is a core patient-reported outcome domain in clinical trials in rheumatic diseases. Frequently used PF measures have ceiling effects, leading to large sample size requirements and low sensitivity to change. In most of these instruments, the response category...... easy, increases the range of precise measurement of self-reported PF. Methods: Three five-item PF short forms were constructed from the Patient-Reported Outcomes Measurement Information System (PROMIS®) wave 1 data. All forms included the same physical activities but varied in item stem and response...... precision between the short forms using different item formats. Results: Sufficient unidimensionality of all short-form items and the original PF item bank was supported. Compared to formats A and B, format C increased the range of reliable measurement by about 0.5 standard deviations on the positive side...

  7. 22nd annual report 2013. Convention on long-range transboundary air pollution. International cooperative programme on integrated monitoring of air pollution effects on ecosystems

    Energy Technology Data Exchange (ETDEWEB)

    Kleemola, S.; Forsius, M. (eds.)

    2013-09-01

    The Integrated Monitoring Programme (ICP IM) is part of the effect-oriented activities under the 1979 Convention on Long-range Transboundary Air Pollution, which covers the region of the United Nations Economic Commission for Europe (UNECE). The main aim of ICP IM is to provide a framework to observe and understand the complex changes occurring in natural/semi natural ecosystems. This report summarizes the work carried out by the ICP IM Programme Centre and several collaborating institutes. The emphasis of the report is in the work done during the programme year 2012/2013 including: A short summary of previous data assessments; A status report of the ICP IM activities, content of the IM database, and geographical coverage of the monitoring network; A final report on relations between vegetation changes and nitrogen Critical Load exceedance; A progress report on base line heavy metal approach, estimation of the extent of metal turnover in European forest catchments over the last decades; A final report on sulphur and nitrogen input-output budgets at ICP IM sites in Europe; National Reports on ICP IM activities are presented as annexes.

  8. Oclusión espontánea de malformación arteriovenosa cerebral parcialmente embolizada: reporte de dos casos Spontaneous occlusion of previously cerebral embolized residual arteriovenous malformation: report of two cases

    Directory of Open Access Journals (Sweden)

    T. Alejandro Torrico

    2006-09-01

    Full Text Available OBJETIVO: Mostrar dos casos de oclusión espontánea de remanente malformativo previamente embolizado y analizar sus probables causas. MÉTODO: Revisión retrospectiva de pacientes con malformaciones arteriovenosas cerebrales (MAV embolizadas entre Enero de 1999 y Agosto de 2005 en nuestra institución y análisis de dos casos de oclusión de MAV remanentes. RESULTADOS: Se presentan dos casos de MAV tratadas por vía endovascular, con remanentes del nido malformativo post-embolización, que posteriormente en controles angiográficos presentan desaparición completa de las lesiones sin mediar otro tratamiento. CONCLUSIÓN: La oclusión espontánea de un remanente arteriovenoso es un hecho infrecuente. Se discuten diversos mecanismos relacionados.OBJECTIVE: To report two cases of spontaneous occlusion of residual malformations that had previously been embolized and to analyze their probable causes. METHOD: Retrospective review of patients with embolized arteriovenous malformations (AVMs between January 1999 and August 2005 in our institution and analysis of two cases of occlusion in residual AVMs. RESULTS: Two cases of AVMs that received endovascular treatment and had post-embolization residual nidus malformation, which in later angiographic controls showed a complete disappearance of the lesions without other treatment. CONCLUSION: The spontaneous occlusion of residual arteriovenous malformations is an infrequent occurrence. Several related mechanisms are discussed.

  9. Range 8C Rehabilitation Demonstration Project, Hohenfels Training Area, Germany: Final report

    Energy Technology Data Exchange (ETDEWEB)

    Zellmer, S.D.; Hinchman, R.R.; Johnson, D.O. (Argonne National Lab., IL (United States). Energy Systems Div.); Severinghaus, W.D. (Corps of Engineers, Champaign, IL (United States)); Brent, J.J. (Army Construction Engineering Research Lab., Champaign, IL (United States))

    1991-11-01

    More than 30 years of intensive and continual tactical training has caused extensive environmental damage at the US Army Hohenfels Training Area in Germany. The Range 8C Rehabilitation Demonstration Project, followed by a three-year monitoring effort, was conducted to develop and evaluate the environmental and economic effectiveness of seven revegetation and four erosion control prescriptions implemented at a 16-ha site. The point-intercept method was used to measure the types and amounts of vegetation established and the changes in the vegetative community during three years of military use on the seven areas treated with revegetation prescriptions. Field observations were made to determine the suitability and durability of four types of erosion control structures. Soil fertility and a source of seed appeared to be the most limiting factors in establishing vegetation, while seedbed preparation had only a minor influence. Grasses appeared to be more resistant to vehicle traffic than did other types of vegetation. Because grassed waterways were used as roads by military vehicles and a system of graded terraces was expensive, these erosion control prescriptions were unsuitable and uneconomical for use on training areas. Low-cost riprap waterbars and porous check dams slowed the velocity of runoff, trapped sediments, and were durable. Recommendations were formulated to improve the environmental and economic effectiveness of future rehabilitation efforts on tactical training areas.

  10. A roadmap to defining the clinical reportable ranges of chemistry analytes: Increasing automation efficiency and decreasing manual dilutions.

    Science.gov (United States)

    Lo, Sheng-Ying; Baird, Geoffrey S; Greene, Dina N

    2015-12-07

    Proper utilization of resources is an important operational objective for clinical laboratories. To reduce unnecessary manual interventions on automated instruments, we conducted a workflow analysis that optimized dilution parameters and reporting of abnormally high chemistry results for the Beckman AU series of chemistry analyzers while maintaining clinically acceptable reportable ranges. Workflow analysis for the Beckman AU680/5812 and DxC800 chemistry analyzers was performed using historical data. Clinical reportable ranges for 53 chemistry analytes were evaluated. Optimized dilution parameters and upper limit of reportable ranges for the AU680/5812 instruments were derived and validated to meet these reportable ranges. The number of specimens that required manual dilutions before and after optimization was determined for both the AU680/5812 and DxC800, with the DxC800 serving as the reference instrument. Retrospective data analysis revealed that 7700 specimens required manual dilutions on the DxC over a 2-y period. Using our optimized AU-specific dilution and reporting parameters, the data-driven simulation analysis showed a 61% reduction in manual dilutions. For the specimens that required manual dilutions on the AU680/5812, we developed standardized dilution procedures to further streamline workflow. We provide a data-driven, practical outline for clinical laboratories to efficiently optimize their use of automated chemistry analyzers. The outcomes can be used to assist laboratories wishing to improve their existing procedures or to facilitate transitioning into a new line of instrumentation, regardless of the instrument model or manufacturer. Copyright © 2015 Elsevier B.V. All rights reserved.

  11. INTRODUCTION Previous reports have documented a high ...

    African Journals Online (AJOL)

    2002; 81(1):58-. 63. 4. Marin C, Segura-Egea JJ, Martinez-Sahuquillo Á and Bullon P. Correlation between infant birth weight and mother's periodontal status. J Clin. Periodontol 2005; 299-304. 5. Jin LJ, Chiu GKC and Corbet EF. Are periodontal diseases risk factors for certain systemic disorders? - What matters to medical.

  12. INTRODUCTION Previous reports have documented a high ...

    African Journals Online (AJOL)

    Assessment of periodontal knowledge and periodontal status of an adult population in Jordan. Int J Dent Hygiene. 2004; 132–136. 12. Machuca G, Khoshfiez O, Lacalle JR, Machuca. C and Bullon P. The influence of general health and socio-cultural variables on the periodontal condition of pregnant women. J Periodontol.

  13. Occurrence of Belonolaimus in Sinaloa, Northwestern Mexico: A New Report on Distribution and Host Range.

    Science.gov (United States)

    Mundo-Ocampo, Manuel; Baldwin, J G; Pereira, T J; Camacho-Baez, J R; Armenta-Bojorquez, A D; Camacho-Haro, M; Becker, J O

    2017-03-01

    The present study reports the occurrence of the genus Belonolaimus in the state of Sinaloa, Mexico, associated with native plants (i.e., Ziziphus amole and Stenocereus alamosensis) in a natural coastal ecosystem. Both morphological and molecular approaches were employed to characterize the Sinaloa population. Notwithstanding of some morphological and morphometric variation between Belonolaimus from Sinaloa and other valid species, the characterization indicates that this population might belong to the Belonolaimus longicaudatus species complex. Molecular analyses based on the 28S gene and ITS1-5.8S-ITS2 regions of the ribosomal RNA (rRNA) identified four major clades within Belonolaimus; however, none of the species including B. longicaudatus, B. gracilis, and B. euthychilus were supported as monophyletic; yet monophyly is argued to be a basic requirement of species status. Sequence divergence among different Belonolaimus populations and species varied according to the rRNA dataset (i.e., ITS1-5.8S-ITS2 > 28S > 18S) used, thus showing the importance of using genes with different rates of evolution to estimate species relationships. The fact that Belonolaimus has not been found in other cultivated (including on suitable hosts) areas in Sinaloa and that this population is relatively distant from the common B. longicaudatus groups (i.e., clades A and B) suggests that its appearance was not due to a recent introduction associated with the local agriculture.

  14. Closure Report for Corrective Action Unit 486: Double Tracks RADSAFE Area Nellis Air Force Range, Nevada

    Energy Technology Data Exchange (ETDEWEB)

    D. H. Cox

    2000-12-01

    The Double Tracks Radiological Safety Area (DTRSA), Corrective Action Unit (CAU) 486, was clean-closed following the approved Corrective Action Decision Document closure alternative and in accordance with the Federal Facility Agreement and Consent Order. The CAU consists of a single Corrective Action Site, 71-23-001-71DT. The DTRSA was used during May 1963 to decontaminate vehicles, equipment, personnel and animals from the Double Tracks Test. Double Tracks was one of four storage-transportation tests. The Double Tracks test was conducted in Stonewall Flat, approximately 32 kilometers (20 miles) east of Goldfield, Nevada, on the Nellis Air Force Range. The Double Tracks Test used a single device containing plutonium and depleted uranium and was designed to investigate the characteristics of plutonium-bearing particulate material formed by the non-nuclear detonation of a nuclear weapon. All facilities associated with the DTRSA operation were removed. Based on available information, the areas of concern at the DTRSA consisted of a decon facility (vehicle decon pad and decon sump) in the southern half of the DTRSA, and a burial pit and former loading/unloading area located in the northern half of the DTRSA. Based on the results of the Corrective Action Investigation, radiological field screening detected elevated gamma and alpha readings on excavated plastic debris. Swipe surveys taken on the plastic debris detected removable alpha. No contaminants were detected above preliminary action levels in soil samples. The debris excavated during the corrective action investigation was not characterized. The clean-closure corrective action consisted of excavation, disposal, verification sampling, backfilling, and regrading. Field activities began on May 1, 2000, and ended on May 10, 2000. Soil that was associated with the radiologically contaminated man-made debris was placed into B-25 bins, moved to the designated waste management area where it was scanned, and hauled off

  15. 20th annual report 2011. Convention on long-range transboundary air pollution. International cooperative programme on integrated monitoring of air pollution effects on ecosystems

    Energy Technology Data Exchange (ETDEWEB)

    Kleemola, S.; Forsius, M. (eds.)

    2011-07-01

    The Integrated Monitoring Programme (ICP IM) is part of the effect-oriented activities under the 1979 Convention on Long-range Transboundary Air Pollution, which covers the region of the United Nations Economic Commission for Europe (UNECE). The main aim of ICP IM is to provide a framework to observe and understand the complex changes occurring in natural/semi natural ecosystems. This report summarizes the work carried out by the ICP IM Programme Centre and several collaborating institutes. The emphasis of the report is in the work done during the programme year 2010/2011 including: A short summary of previous data assessments, a status report of the ICP IM activities, content of the IM database, and geographical coverage of the monitoring network, a review of published vegetation results from ICP IM and preliminary analyses of collected vegetation data, a report on updated heavy metal budgets and critical loads at ICP IM sites, report on benefits of LTER collaboration (Long Term Ecological Research network, www.lter-europe.net), National Reports on ICP IM activities are presented as annexes. (orig.)

  16. Archaeological Survey at Fort Hood, Texas Fiscal Year 1987: The MCA range Construction, Pidcoke Land Exchange, and Phantom Range Projects. Archeological Resource Management Series Research Report Number 23

    Science.gov (United States)

    1991-01-01

    iron pocket knife and a brass razor head (1899+). This site is reported to be in good condition, with 25% of the surface area affected by military...glaze bowl - rim with gold decoration with molded/ gilded rim 41BL0951 050-0012 1 Lavender glass bottle lip/neck improved tooled (1880--1915) 41BL0951...body with undecorated decoration (1900--1988) 41BL0951 050-0025 1 Iron pocket knife 41BL0951 050-0026 1 Brass razor head (1899--1988) 41BL0952 050

  17. Successful adalimumab treatment of a psoriasis vulgaris patient with hemodialysis for renal failure: A case report and a review of the previous reports on biologic treatments for psoriasis patients with hemodialysis for renal failure.

    Science.gov (United States)

    Kusakari, Yoshiyuki; Yamasaki, Kenshi; Takahashi, Toshiya; Tsuchiyama, Kenichiro; Shimada-Omori, Ryoko; Nasu-Tamabuchi, Mei; Aiba, Setsuya

    2015-07-01

    The efficacy and safety of biologic treatments have been established in patients with moderate to severe psoriasis, but there are few reports on biologic therapy for patients with psoriasis complicated by end-stage renal failure on hemodialysis (HD). In this report, we demonstrated the efficacy and safety of adalimumab for patients with severe psoriasis on HD. A 46-year-old Japanese man with a 14-year history of psoriasis was referred to our clinic in September 2009. He had developed hypertension and renal failure during a 7-year history of cyclosporin treatment. With the infliximab treatment, he achieved 75% improvement of the Psoriasis Area and Severity Index (PASI) score within 3 months from the PASI of 42.3 before the treatment. However, his renal failure gradually deteriorated, and HD was initiated at 1 year after the introduction of infliximab. Because of hydration during the i.v. injection of infliximab, he developed pulmonary edema with every infliximab treatment after starting HD. We switched to ustekinumab treatment, but his psoriasis was not improved. Then, we switched to adalimumab and achieved a PASI-100 response within 2 months. The patient received adalimumab treatment for more than a year without any adverse effects. In addition to our case, five articles reported cases of psoriasis patients with renal failure on HD who were treated with biologics. The psoriatic lesions were improved by biologics in these cases, and no severe adverse effects on the renal function were reported. Thus, biologics are a reasonable treatment option for patients with severe psoriasis with renal failure on HD. © 2015 Japanese Dermatological Association.

  18. 2013 Annual Site Environmental Report for Sandia National Laboratories Tonopah Test Range Nevada & Kauai Test Facility Hawaii

    Energy Technology Data Exchange (ETDEWEB)

    Griffith, Stacy Rene [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Agogino, Karen [National Nuclear Security Administration (NNSA), Washington, DC (United States); Li, Jun [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); White, Nancy [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Minitrez, Alexandra [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Avery, Penny [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Bailey-White, Brenda [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Bonaguidi, Joseph [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Catechis, Christopher [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); duMond, Michael [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Eckstein, Joanna [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Evelo, Stacie [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Forston, William [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Herring, III, Allen [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Lantow, Tiffany [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Martinez, Reuben [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Mauser, Joseph [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Miller, Amy [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Miller, Mark [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Payne, Jennifer [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Peek, Dennis [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Reiser, Anita [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Ricketson, Sherry [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Roma, Charles [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Salinas, Stephanie [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Ullrich, Rebecca [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States)

    2014-08-01

    Tonopah Test Range (TTR) in Nevada and Kauai Test Facility (KTF) in Hawaii are government-owned, contractor-operated facilities managed and operated by Sandia Corporation (Sandia), a wholly owned subsidiary of Lockheed Martin Corporation. The U.S. Department of Energy (DOE), National Nuclear Security Administration (NNSA), through the Sandia Field Office (SFO), in Albuquerque, New Mexico, administers the contract and oversees contractor operations at TTR and KTF. Sandia manages and conducts operations at TTR in support of the DOE/NNSA’s Weapons Ordnance Program and has operated the site since 1957. Navarro Research and Engineering subcontracts to Sandia in administering most of the environmental programs at TTR. Sandia operates KTF as a rocket preparation launching and tracking facility. This Annual Site Environmental Report summarizes data and the compliance status of the sustainability, environmental protection, and monitoring program at TTR and KTF through Calendar Year 2013. The compliance status of environmental regulations applicable at these sites include state and federal regulations governing air emissions, wastewater effluent, waste management, terrestrial surveillance, Environmental Restoration (ER) cleanup activities, and the National Environmental Policy Act. Sandia is responsible only for those environmental program activities related to its operations. The DOE/NNSA/Nevada Field Office retains responsibility for the cleanup and management of TTR ER sites. Environmental monitoring and surveillance programs are required by DOE Order 231.1B, Environment, Safety, and Health Reporting (DOE 2012).

  19. Calendar year 2002 annual site environmental report for Tonopah Test Range, Nevada and Kauai Test Facility, Hawaii.

    Energy Technology Data Exchange (ETDEWEB)

    Wagner, Katrina; Sanchez, Rebecca V.; Mayeux, Lucie; Koss, Susan I.; Salinas, Stephanie A.

    2003-09-01

    Tonopah Test Range (TTR) in Nevada and Kauai Test Facility (KTF) in Hawaii are government-owned, contractor-operated facilities operated by Sandia Corporation, a subsidiary of Lockheed Martin Corporation. The U.S. Department of Energy (DOE), National Nuclear Security Administration (NNSA), through the Sandia Site Office (SSO), in Albuquerque, NM, oversees TTR and KTF's operations. Sandia Corporation conducts operations at TTR in support of DOE/NNSA's Weapons Ordnance Program and has operated the site since 1957. Westinghouse Government Services subcontracts to Sandia Corporation in administering most of the environmental programs at TTR. Sandia Corporation operates KTF as a rocket preparation launching and tracking facility. This Annual Site Environmental Report (ASER) summarizes data and the compliance status of the environmental protection and monitoring program at TTR and KTF through Calendar Year (CY) 2002. The compliance status of environmental regulations applicable at these sites include state and federal regulations governing air emissions, wastewater effluent, waste management, terrestrial surveillance, and Environmental Restoration (ER) cleanup activities. Sandia Corporation is responsible only for those environmental program activities related to its operations. The DOE/NNSA, Nevada Site Office (NSO) retains responsibility for the cleanup and management of ER TTR sites. Currently, there are no ER Sites at KTF. Environmental monitoring and surveillance programs are required by DOE Order 5400.1, General Environmental Protection Program (DOE 1990) and DOE Order 231.1, Environment, Safety, and Health Reporting (DOE 1996).

  20. Calendar year 2003 : annual site enviromental report for Tonopah Test Range, Nevada and Kauai Test Facility, Hawaii.

    Energy Technology Data Exchange (ETDEWEB)

    Wagner, Katrina; Sanchez, Rebecca V.; Mayeux, Lucie; Koss, Susan I.; Salinas, Stephanie A.

    2004-09-01

    Tonopah Test Range (TTR) in Nevada and Kauai Test Facility (KTF) in Hawaii are government-owned, contractor-operated facilities operated by Sandia Corporation, a subsidiary of Lockheed Martin Corporation. The U.S. Department of Energy (DOE), National Nuclear Security Administration (NNSA), through the Sandia Site Office (SSO), in Albuquerque, NM, manages TTR and KTF's operations. Sandia Corporation conducts operations at TTR in support of DOE/NNSA's Weapons Ordnance Program and has operated the site since 1957. Westinghouse Government Services subcontracts to Sandia Corporation in administering most of the environmental programs at TTR. Sandia Corporation operates KTF as a rocket preparation launching and tracking facility. This Annual Site Environmental Report (ASER) summarizes data and the compliance status of the environmental protection and monitoring program at TTR and KTF through Calendar Year (CY) 2003. The compliance status of environmental regulations applicable at these sites include state and federal regulations governing air emissions, wastewater effluent, waste management, terrestrial surveillance, and Environmental Restoration (ER) cleanup activities. Sandia Corporation is responsible only for those environmental program activities related to its operations. The DOE/NNSA, Nevada Site Office (NSO) retains responsibility for the cleanup and management of ER TTR sites. Currently, there are no ER Sites at KTF. Environmental monitoring and surveillance programs are required by DOE Order 450.1, Environmental Protection Program (DOE 2003) and DOE Order 231.1 Chg 2., Environment, Safety, and Health Reporting (DOE 1996).

  1. Calendar year 2007 annual site environmental report for Tonopah Test Range, Nevada and Kauai Test Facility, Hawaii,

    Energy Technology Data Exchange (ETDEWEB)

    Agogino, Karen [Department of Energy, Albuquerque, NM (United States). National Nuclear Security Administration (NNSA); Sanchez, Rebecca [Sandia Corp., Albuquerque, NM (United States)

    2008-09-30

    Tonopah Test Range (TTR) in Nevada and Kauai Test Facility (KTF) in Hawaii are government-owned, contractor-operated facilities operated by Sandia Corporation (Sandia), a wholly owned subsidiary of Lockheed Martin Corporation. The U.S. Department of Energy (DOE)/National Nuclear Security Administration (NNSA), through the Sandia Site Offi ce (SSO), in Albuquerque, NM, administers the contract and oversees contractor operations at TTR and KTF. Sandia manages and conducts operations at TTR in support of the DOE/NNSA’s Weapons Ordnance Program and has operated the site since 1957. Washington Group International subcontracts to Sandia in administering most of the environmental programs at TTR. Sandia operates KTF as a rocket preparation launching and tracking facility. This Annual Site Environmental Report (ASER) summarizes data and the compliance status of the environmental protection and monitoring program at TTR and KTF through Calendar Year (CY) 2007. The compliance status of environmental regulations applicable at these sites include state and federal regulations governing air emissions, wastewater effluent, waste management, terrestrial surveillance, and Environmental Restoration (ER) cleanup activities. Sandia is responsible only for those environmental program activities related to its operations. The DOE/NNSA/Nevada Site Offi ce (NSO) retains responsibility for the cleanup and management of ER TTR sites. Currently, there are no ER Sites at KTF. Environmental monitoring and surveillance programs are required by DOE Order 450.1, Environmental Protection Program (DOE 2007a) and DOE Manual 231.1-1A, Environment, Safety, and Health Reporting Manual (DOE 2007).

  2. Post-Closure Inspection Report for the Tonopah Test Range, Nevada. For Calendar Year 2015, Revision 0

    Energy Technology Data Exchange (ETDEWEB)

    Matthews, Patrick [Navarro, Las Vegas, NV (United States); Petrello, Jaclyn [Navarro, Las Vegas, NV (United States)

    2016-03-01

    This report provides the results of the annual post-closure inspections conducted at the closed corrective action units (CAUs) located on the Tonopah Test Range (TTR), Nevada. This report covers calendar year 2015 and includes inspection and repair activities completed at the following CAUs; CAU 400: Bomblet Pit and Five Points Landfill (TTR); CAU 407: Roller Coaster RadSafe Area (TTR); CAU 424: Area 3 Landfill Complexes (TTR); CAU 453: Area 9 UXO Landfill (TTR); and CAU 487: Thunderwell Site (TTR) Inspections were conducted according to the post-closure plans in the approved closure reports and subsequent correspondence with the Nevada Division of Environmental Protection. The post-closure inspection plans and subsequent correspondence modifying the requirements for each CAU are included in Appendix B. The inspection checklists are included in Appendix C. Field notes are included in Appendix D. The annual post-closure inspections were conducted on May 12, 2015. Maintenance was required at CAU 453. Cracking along the north trench was repaired. One monument is missing at CAU 424; it will be replaced in 2016. Postings at CAUs 407, 424, 453, and 487 contain contact information for TTR Security. It was noted that protocols may not be in place to ensure that the U.S. Department of Energy, National Nuclear Security Administration Nevada Field Office (NNSA/NFO) is notified if access is needed at these sites. NNSA/NFO is working with the U.S. Air Force and Sandia to determine whether more appropriate contact information or new protocols are warranted for each CAU. Based on these inspections, there has not been a significant change in vegetation, and vegetation monitoring was not recommended at CAU 400 or CAU 407 in 2015.

  3. HIV risk perception and testing behaviours among men having sex with men (MSM reporting potential transmission risks in the previous 12 months from a large online sample of MSM living in Germany

    Directory of Open Access Journals (Sweden)

    Ulrich Marcus

    2016-10-01

    Full Text Available Abstract Background HIV testing and serostatus awareness are essential to implement biomedical strategies (treatment as prevention; oral chemoprophylaxis, and for effective serostatus-based behaviours (HIV serosorting; strategic positioning. The analysis focuses on the associations between reported sexual risks, the perceived risk for HIV infection, and HIV testing behaviour in order to identify the most relevant barriers for HIV test uptake among MSM living in Germany. Methods MSM were recruited to a nationwide anonymous online-survey in 2013 on MSM social networking/dating sites. Questions covered testing behaviours, reasons for testing decisions, and HIV risk perception (5-point scale. Additional questions addressed arguments in favour of home/ home collection testing (HT. Using descriptive statistics and logistic regression we compared men reporting recent HIV testing (RT; previous 12 month with men never tested (NT in a subsample not previously diagnosed with HIV and reporting ≥2 episodes of condomless anal intercourse (CLAI with a non-steady partner of unknown HIV serostatus in the previous 12 months. Results The subsample consisted of 775 RT (13 % of RT and 396 NT (7 % of NT. The number of CLAI episodes in the last 12 months with non-steady partners of unknown HIV status did not differ significantly between the groups, but RT reported significantly higher numbers of partners (>5 AI partners: 65 vs. 44 %. While perceived risks regarding last AI were comparable between the groups, 49vs. 30 % NT were <30 years, lived more often in towns/villages <100,000 residents (60 vs. 39 %, were less out-particularly towards care providers-about being attracted to men (aOR 10.1; 6.9–14.8, more often identified as bisexual (aOR 3.5; 2.5–4.8, and reported lower testing intentions (aOR 0.08; 0.06–0.11. Perceived risks (67 % and routine testing (49 % were the most common testing reasons for RT, while the strong belief not to be infected

  4. Isokinetic trunk strength and lumbosacral range of motion in elite female field hockey players reporting low back pain.

    Science.gov (United States)

    Fenety, A; Kumar, S

    1992-01-01

    This study was funded, in part, by a Small Faculties Grant from the University of Alberta. Physical therapists have reported an increased incidence of low back pain (LBP) in female field hockey (FH) players, commonly accompanied by decreased trunk range of motion (ROM) and strength. The purpose of this study was to compare lumbosacral sagittal ROM and isokinetic trunk strength in three groups of women: 1) FH athletes with a history of chronic LBP, 2) pain-free FH athletes, and 3) an age-matched, healthy nonathletic control group. Photographs (35 mm) of subjects wearing spinal motion markers were used to determine the limits of lumbosacral saggital ROM in standing. Eccentric and concentric isokinetic trunk flexion and extension torques were measured in sitting through 60 degrees of trunk movement using a Kin-Com dynamometer set at 60 degrees /sec. The ANOVA showed that the pain group had 12 degrees and 18 degrees less extension (p pain-free and control groups, respectively. Only peak (p pain group than in the nonathletic control group. These results suggest that physical therapists should perform preseason screening of trunk strength and lumbosacral ROM. In-season trunk extension stretching and strengthening is needed in the training regimes of these athletes. J Orthop Sports Phys Ther 1992;16(3):129-135.

  5. Range and trend of expected toxicity level (ETL) in standard A + B designs: a report from the Children's Oncology Group.

    Science.gov (United States)

    Chen, Zhengjia; Krailo, Mark D; Sun, Junfeng; Azen, Stanley P

    2009-03-01

    The traditional algorithm-based 3+3 designs are most widely used for their practical simplicity in phase I clinical trials. At early stage, a common belief was that the expected toxicity level (ETL) at the maximum tolerated dose (MTD) should be 33% [Storer, B. Design and analysis of phase I clinical trials. Biometrics 1989;45;925-937, Gorden, N., Willson, J. Using toxicity grades in the design and analysis of cancer phase I clinical trials. Statistics in Medicine 1992; 11: 2063-2075, Mick, R. Phase I Clinical Trial Design. In Schilsky, R., Milano, G., Ratain, M., eds. Principles of Antineoplastic Drug Development and Pharmacology New York, NY: Marcel Dekker, 1996; 29-36]. Recently, Kang and Ahn [Kang, S., Ahn, C. The expected toxicity rate at the maximum tolerated dose in the standard phase I cancer clinical trial design. Drug Information Journal 2001; 35:1189-1199, Kang, S., Ahn, C. An investigation of the traditional algorithm-based designs for phase I cancer clinical trials. Drug Information Journal 2002; 36:865-873] found that the ETL is between 17% and 21% and He et al [He, W., Liu, J., Binkowitz, B., Quan, H. A model-based approach in the estimation of the maximum tolerated dose in phase I cancer clinical trials. Statistics in Medicine 2006; 25(12):2027-42] further reported that the ETL ranges from 19% to 24%. However they only investigated designs where the number of dose levels was at most 20. It has practical significance in designing and conducting phase I clinical trial to definitely assess the full range and trend of ETL by all possible number of tested dose levels in traditional algorithm-based A+B designs, especially 3+3 designs. In this simulation study, we originally find that the ETL decreases monotonically from about 30% to 0% as the number of dose levels increase from 3 to infinity, which will correct the inaccuracy in the common belief among phase I trial investigators. To help better design and conduct phase I trials, we create a table as a

  6. A revised geographical range for Liolaemus elongates Koslowsky, 1896 (Squamata: Liolaemini in Argentina: review of reported and new-data based distribution with new localities

    Directory of Open Access Journals (Sweden)

    Ignacio Minoli

    2013-12-01

    Full Text Available Estimating the effective geographical ranges of species is central to species-oriented conservation and management. In this paper, we review the geographical distribution of Liolaemus elongatus Koslowsky, 1896 with three new records for northern Chubut and southern Río Negro provinces, Argentina. Based on detailed locality records pooled from multiple data sources, including new records obtained for this study, we revise the range of L. elongatus sensu stricto and provide geographical distribution maps comparing the previously recognized range to that proposed herein. Our results show that L. elongatus possesses a much more limited geographic distribution than previously thought, being restricted to areas south of 38°S latitude; the newly proposed range is merely half the species formerly recognized geographical distribution.

  7. Closure Report for Corrective Action Unit 408: Bomblet Target Area Tonopah Test Range (TTR), Nevada, Revision 0

    Energy Technology Data Exchange (ETDEWEB)

    Mark Krauss

    2010-09-01

    This Closure Report (CR) presents information supporting the closure of Corrective Action Unit (CAU) 408: Bomblet Target Area (TTR), Tonopah Test Range, Nevada. This CR complies with the requirements of the Federal Facility Agreement and Consent Order that was agreed to by the State of Nevada; U.S. Department of Energy (DOE), Environmental Management; U.S. Department of Defense; and DOE, Legacy Management. Corrective Action Unit 408 is located at the Tonopah Test Range, Nevada, and consists of Corrective Action Site (CAS) TA-55-002-TAB2, Bomblet Target Areas. This CAS includes the following seven target areas: • Mid Target • Flightline Bomblet Location • Strategic Air Command (SAC) Target Location 1 • SAC Target Location 2 • South Antelope Lake • Tomahawk Location 1 • Tomahawk Location 2 The purpose of this CR is to provide documentation supporting the completed corrective actions and data confirming that the closure objectives for the CAS within CAU 408 were met. To achieve this, the following actions were performed: • Review the current site conditions, including the concentration and extent of contamination. • Implement any corrective actions necessary to protect human health and the environment. • Properly dispose of corrective action and investigation wastes. • Document Notice of Completion and closure of CAU 408 issued by the Nevada Division of Environmental Protection. From July 2009 through August 2010, closure activities were performed as set forth in the Streamlined Approach for Environmental Restoration Plan for CAU 408: Bomblet Target Area, Tonopah Test Range (TTR), Nevada. The purposes of the activities as defined during the data quality objectives process were as follows: • Identify and remove munitions of explosive concern (MEC) associated with DOE activities. • Investigate potential disposal pit locations. • Remove depleted uranium-contaminated fragments and soil. • Determine whether contaminants of concern (COCs) are

  8. Quarterly report on reservation wild life and activities appurtenant thereto, from July 1, 1934 to September 30, 1934 inclusive: [National Bison Range

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This narrative report summarizes conditions on the National Bison Range between July and September, 1934. Wildlife, birds, grazing, fire prevention, improvement and...

  9. Narrative report: Calendar year 1976: Charles M. Russell National Wildlife Range and Hailstone, Halfbreed, Lake Mason & War Horse National Wildlife Refuges

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This narrative report for Charles M. Russell National Wildlife Range (including the satellite refuges) outlines Refuge accomplishments during the 1976 calendar year....

  10. Cryptococcus neoformans granuloma in the lung and spinal cord of a free-ranging cheetah (Acinonyx jubatus. A clinical report and literature review : clinical communication

    Directory of Open Access Journals (Sweden)

    I.R. Millward

    2005-06-01

    Full Text Available A 6-year-old, male, wild-born, free-ranging cheetah (Acinonyx jubatus was evaluated for acute onset of progressive lameness in the right hind limb. Survey radiographs were unrewarding and myelography indicated an intramedullary compressive mass at the L3-L4 region. A fine needle aspirate of the lesion indicated the presence of Cryptococcus organisms. Necropsy confirmed the presence of granulomas (cryptococcoma in the lung and the spinal cord (meningomyelitis caused by Cryptococcus neoformans var. gattii. Cryptococcus neoformans is a yeast-like organism that is a potential pathogen to many species. Initial infection is thought to be of respiratory origin and then it commonly disseminates systemically from the nasal cavity or lungs to the skin, eyes and central nervous system in particular. The cheetah tested negative for both feline leukaemia virus (FeLV and feline immunodeficiency virus (FIV, as have all the previously reported cheetah cases. C. neoformans is a non-contagious, opportunistic organism and is the most common systemic mycoses in domestic cats and the cheetah.

  11. Narrative report 1970: Charles M. Russell National Wildlife Range and Hailstone, Halfbreed, Mason, Yellow Water, War Horse & Wild Horse

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This annual narrative report for Charles M. Russell NWR (including the satellite refuges) outlines Refuge accomplishments during the 1970 calendar year. The report...

  12. Narrative report FY 1975: Charles M. Russell National Wildlife Range and Hailstone, Halfbreed, Lake Mason & War Horse Wildlife Refuges

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This annual narrative report for Charles M. Russell NWR (including the satellite refuges) outlines Refuge accomplishments during the 1975 fiscal year. The report...

  13. Narrative report FY 1974: Charles M. Russell National Wildlife Range and Hailstone, Halfbreed, Lake Mason & War Horse Wildlife Refuges

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This annual narrative report for Charles M. Russell NWR (including the satellite refuges) outlines Refuge accomplishments during the 1974 fiscal year. The report...

  14. A novel vaporization-enucleation technique for benign prostate hyperplasia using 120-W HPS GreenLight™ laser: Seoul technique II in comparison with vaporization and previously reported modified vaporization-resection technique.

    Science.gov (United States)

    Yoo, Sangjun; Park, Juhyun; Cho, Sung Yong; Cho, Min Chul; Jeong, Hyeon; Son, Hwancheol

    2017-12-01

    We developed a novel vaporization-enucleation technique (Seoul II), which consists of vaporization-enucleation of the prostate using 120-W HPS GreenLight laser, and enucleated prostate resection using bipolar devices for tissue removal. We compared the outcomes of the Seoul II with vaporization and a previously reported modified vaporization-resection technique (Seoul I). Among patients with benign prostate hyperplasia who underwent transurethral surgery using GreenLight laser at our institute, 347 patients with prostate volume ≥ 40 ml were included. The impact of surgical techniques on efficacy and postoperative functional outcomes was compared. No difference was found in baseline characteristics, although the prostate volume was marginally greater in Seoul II (p = 0.051). Prostate volume reduction per operation time (p techniques. In multivariate analysis, postoperative 12-month I-PSS for Seoul II was significantly superior to vaporization (p vaporization (p = 0.014) and Seoul I (p = 0.048). Seoul II showed improved efficacy and voiding functional maintenance over postoperative 12 months in patients with prostate volume ≥ 40 ml compared with vaporization and Seoul I. This technique could be easily accepted by clinicians who are familiar with GreenLight lasers and add flexibility to surgery without additional equipment.

  15. Functional Outcomes and Health-Related Quality of Life After Surgical Repair of Full-Thickness Rotator Cuff Tears Using a Mini-Open Technique: A Concise 10-Year Follow-up of a Previous Report.

    Science.gov (United States)

    Saraswat, Manoj K; Styles-Tripp, Fiona; Beaupre, Lauren A; Luciak-Corea, Charlene; Otto, David; Lalani, Aleem; Balyk, Robert A

    2015-11-01

    Although good short-term and midterm outcomes are reported for mini-open rotator cuff repair, few prospective studies have investigated long-term results. Function and health-related quality of life (HRQL) outcomes would be maintained 10 years after mini-open rotator cuff repair. Cohort study; Level of evidence, 2. Patients with a confirmed full-thickness rotator cuff tear who underwent mini-open repair between April 1997 and July 2000 were evaluated preoperatively as well as 1 year and 10 years postoperatively for (1) pain, function, and HRQL using the American Shoulder and Elbow Surgeons (ASES) score and Western Ontario Rotator Cuff Index (WORC) score; (2) active shoulder range of motion (ROM) using goniometry; and (3) satisfaction by an independent evaluator. Changes in function, HRQL, and ROM over time were analyzed using repeated-measures analysis of variance. A total of 84 patients were enrolled, of which 61 (73%) were men; the mean (±SD) age was 53.0 ± 9.9 years. At 10 years, 4 (5%) patients were deceased, and 4 (5%) had symptomatic retears. Fifty-nine (74%) patients were evaluated, composed of 43 (73%) men; 26 (44%) were younger than 60 years. Function and HRQL significantly improved over the course of follow-up (P .06). Postoperative improvements in function and HRQL after mini-open rotator cuff repair were retained at 10 years. © 2015 The Author(s).

  16. Classification of organisms previously reported as the SP and Stewart-Letscher groups, with descriptions of Necropsobacter gen. nov. and of Necropsobacter rosorum sp. nov. for organisms of the SP group.

    Science.gov (United States)

    Christensen, H; Korczak, B M; Bojesen, A M; Kuhnert, P; Frederiksen, W; Bisgaard, M

    2011-08-01

    To allow classification of bacteria previously reported as the SP group and the Stewart-Letscher group, 35 isolates from rodents (21), rabbits (eight), a dog and humans (five) were phenotypically and genotypically characterized. Comparison of partial rpoB sequences showed that 34 of the isolates were closely related, demonstrating at least 97.4 % similarity. 16S rRNA gene sequence comparison of 20 selected isolates confirmed the monophyly of the SP group and revealed 98.5 %-100 % similarity between isolates. A blast search using the 16S rRNA gene sequences showed that the highest similarity outside the SP group was 95.5 % to an unclassified rat isolate. The single strain, P625, representing the Stewart-Letscher group showed the highest 16S rRNA gene similarity (94.9-95.5 %) to members of the SP group. recN gene sequence analysis of 11 representative strains resulted in similarities of 97-100 % among the SP group strains, which showed 80 % sequence similarity to the Stewart-Letscher group strain. Sequence similarity values based on the recN gene, indicative for whole genome similarity, showed the SP group being clearly separated from established genera, whereas the Stewart-Letscher group strain was associated with the SP group. A new genus, Necropsobacter gen. nov., with only one species, Necropsobacter rosorum sp. nov., is proposed to include all members of the SP group. The new genus can be separated from existing genera of the family Pasteurellaceae by at least three phenotypic characters. The most characteristic properties of the new genus are that haemolysis is not observed on bovine blood agar, positive reactions are observed in the porphyrin test, acid is produced from (+)-L-arabinose, (+)-D-xylose, dulcitol, (+)-D-galactose, (+)-D-mannose, maltose and melibiose, and negative reactions are observed for symbiotic growth, urease, ornithine decarboxylase and indole. Previous publications have documented that both ubiquinones and demethylmenaquinone were

  17. Current Practices of Measuring and Reference Range Reporting of Free and Total Testosterone in the United States.

    Science.gov (United States)

    Le, Margaret; Flores, David; May, Danica; Gourley, Eric; Nangia, Ajay K

    2016-05-01

    The evaluation and management of male hypogonadism should be based on symptoms and on serum testosterone levels. Diagnostically this relies on accurate testing and reference values. Our objective was to define the distribution of reference values and assays for free and total testosterone by clinical laboratories in the United States. Upper and lower reference values, assay methodology and source of published reference ranges were obtained from laboratories across the country. A standardized survey was reviewed with laboratory staff via telephone. Descriptive statistics were used to tabulate results. We surveyed a total of 120 laboratories in 47 states. Total testosterone was measured in house at 73% of laboratories. At the remaining laboratories studies were sent to larger centralized reference facilities. The mean ± SD lower reference value of total testosterone was 231 ± 46 ng/dl (range 160 to 300) and the mean upper limit was 850 ± 141 ng/dl (range 726 to 1,130). Only 9% of laboratories where in-house total testosterone testing was performed created a reference range unique to their region. Others validated the instrument recommended reference values in a small number of internal test samples. For free testosterone 82% of laboratories sent testing to larger centralized reference laboratories where equilibrium dialysis and/or liquid chromatography with mass spectrometry was done. The remaining laboratories used published algorithms to calculate serum free testosterone. Reference ranges for testosterone assays vary significantly among laboratories. The ranges are predominantly defined by limited population studies of men with unknown medical and reproductive histories. These poorly defined and variable reference values, especially the lower limit, affect how clinicians determine treatment. Copyright © 2016 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

  18. The effects of mobilization with movement on dorsiflexion range of motion, dynamic balance, and self-reported function in individuals with chronic ankle instability.

    Science.gov (United States)

    Gilbreath, Julie P; Gaven, Stacey L; Van Lunen, L; Hoch, Matthew C

    2014-04-01

    Previous studies have examined the effectiveness of a manual therapy intervention known as Mobilization with Movement (MWM) to increase dorsiflexion range of motion (ROM) in individuals with chronic ankle instability (CAI). While a single talocrural MWM treatment has increased dorsiflexion ROM in these individuals, examining the effects of multiple treatments on dorsiflexion ROM, dynamic balance, and self-reported function would enhance the clinical application of this intervention. This study sought to determine if three treatment sessions of talocrural MWM would improve dorsiflexion ROM, Star Excursion Balance Test (SEBT) reach distances, and self-reported function using the Foot and Ankle Ability Measure (FAAM) in individuals with CAI. Eleven participants with CAI (5 Males, 6 Females, age: 21.5 ± 2.2 years, weight: 83.9 ± 15.6 kg, height: 177.7 ± 10.9 cm, Cumberland Ankle Instability Tool: 17.5 ± 4.2) volunteered in this repeated-measures study. Subjects received three MWM treatments over one week. Weight-bearing dorsiflexion ROM (cm), normalized SEBT reach distances (%), and self-reported function (%) were assessed one week before the intervention (baseline), prior to the first MWM treatment (pre-intervention), and 24–48 h following the final treatment (post-intervention). No significant changes were identified in dorsiflexion ROM, SEBT reach distances, or the FAAM-Activities of Daily Living scale (p > 0.05). Significant changes were identified on the FAAM-Sport (p = 0.01). FAAM-Sport scores were significantly greater post-intervention (86.82 ± 9.18%) compared to baseline (77.27 ± 11.09%; p = 0.01) and pre-intervention (79.82 ± 13.45%; p = 0.04). These results indicate the MWM intervention did not improve dorsiflexion ROM, dynamic balance, or patient-centered measures of activities of daily living. However, MWM did improve patient-centered measures of sport-related activities in individuals with CAI.

  19. Rebound Of Previously Compressed O-Ring

    Science.gov (United States)

    Moore, Carleton J.

    1988-01-01

    Report presents theoretical and experimental analysis of relaxation characteristics of O-ring of vinylidene fluoride/hexafluoropropylene copolymer of same composition used in solid rocket boosters on Space Shuttle flight 51-L. Study covers range of temperatures from 10 to 120 degree F. Presents one-dimensional mathematical model of response provided for both elastic response and creep.

  20. Report on the Development of a Close Range Photogrammetry (CRP) Educational Technician Program (Museum and Archive Use).

    Science.gov (United States)

    Kobelin, Joel

    A close range photogrammetry (CRP) technician training program was developed at Miami-Dade Community College and used to teach the technology to 16 students. Although the results of the study show that it is possible to teach CRP in a two-year program, the technology is too new in the United States to support a sustaining educational program. The…

  1. Associations of self-report measures with gait, range of motion and proprioception in patients with lumbar spinal stenosis.

    Science.gov (United States)

    Conrad, Bryan P; Shokat, Maximilian S; Abbasi, Abdullah Z; Vincent, Heather K; Seay, Amanda; Kennedy, David J

    2013-09-01

    Spinal stenosis is defined as neurogenic claudication due to narrowing of the spinal canal lumen diameter. As the disease progresses, ambulation and gait may be impaired. Self-report measures are routinely used in the clinical setting to capture data related to lumbar pain symptoms, function and perceived disability. The associations between self-report measures and objective measures of physical function in patients with lumbar spinal stenosis are not well characterized. The purpose of this study was to determine the correlation between self-reported assessments of function with objective biomechanical measures of function. 25 subjects were enrolled in this study. Subjects completed self-report questionnaires and biomechanical assessments of gait analysis, lumbar 3D ROM and lumbar proprioception. Correlations were determined between self-report measures and biomechanical data. The Oswestry Disability Index (ODI) was strongly correlated with stride length and gait velocity and weakly correlated with base of support. ODI was also weakly correlated with left lateral bending proprioception but not right lateral bending. The SF12 was not significantly correlated with any of the biomechanical measurements. Pain scores were weakly correlated with velocity, and base of support, and had no correlation any of the other biomechanical measures. There is a strong correlation between gait parameters and functional disability as measured with the ODI. Quantified gait analysis can be a useful tool to evaluate patients with lumbar spinal stenosis and to assess the outcomes of treatments on this group of patients. Copyright © 2013 Elsevier B.V. All rights reserved.

  2. Bilateral orbital infarction and retinal detachment in a previously ...

    African Journals Online (AJOL)

    Bone infarction involving the orbit in sickle cell disease is not common. Bilateral orbital infarction in a previously undiagnosed sickle cell hemoglobinopathy has not been previously reported. In this report, we present a case of an 11‑year‑old previously undiagnosed sickle cell disease Nigerian girl with severe acute bilateral ...

  3. European Union emission inventory report 1990-2008 : under the UNECE Convention on Long-range Transboundary Air Pollution (LRTAP)

    Science.gov (United States)

    2010-07-01

    This report describes the EU27 emission trends for : a number of air pollutants for the period 19902008. : An improved gap-filling methodology used in : compiling this year's EU27 emission inventory : means that for the first time a complete...

  4. Quality of life with palbociclib plus fulvestrant in previously treated hormone receptor-positive, HER2-negative metastatic breast cancer: patient-reported outcomes from the PALOMA-3 trial.

    Science.gov (United States)

    Harbeck, N; Iyer, S; Turner, N; Cristofanilli, M; Ro, J; André, F; Loi, S; Verma, S; Iwata, H; Bhattacharyya, H; Puyana Theall, K; Bartlett, C H; Loibl, S

    2016-06-01

    In the PALOMA-3 study, palbociclib plus fulvestrant demonstrated improved progression-free survival compared with fulvestrant plus placebo in hormone receptor-positive, HER2- endocrine-resistant metastatic breast cancer (MBC). This analysis compared patient-reported outcomes (PROs) between the two treatment groups. Patients were randomized 2 : 1 to receive palbociclib 125 mg/day orally for 3 weeks followed by 1 week off (n = 347) plus fulvestrant (500 mg i.m. per standard of care) or placebo plus fulvestrant (n = 174). PROs were assessed on day 1 of cycles 1-4 and of every other subsequent cycle starting with cycle 6 using the EORTC QLQ-C30 and its breast cancer module, QLQ-BR23. High scores (range 0-100) could indicate better functioning/quality of life (QoL) or worse symptom severity. Repeated-measures mixed-effect analyses were carried out to compare on-treatment overall scores and changes from baseline between treatment groups while controlling for baseline. Between-group comparisons of time to deterioration in global QoL and pain were made using an unstratified log-rank test and Cox proportional hazards model. Questionnaire completion rates were high at baseline and during treatment (from baseline to cycle 14, ≥95.8% in each group completed ≥1 question on the EORTC QLQ-C30). On treatment, estimated overall global QoL scores significantly favored the palbociclib plus fulvestrant group [66.1, 95% confidence interval (CI) 64.5-67.7 versus 63.0, 95% CI 60.6-65.3; P = 0.0313]. Significantly greater improvement from baseline in pain was also observed in this group (-3.3, 95% CI -5.1 to -1.5 versus 2.0, 95% CI -0.6 to 4.6; P = 0.0011). No significant differences were observed for other QLQ-BR23 functioning domains, breast or arm symptoms. Treatment with palbociclib plus fulvestrant significantly delayed deterioration in global QoL (P Palbociclib plus fulvestrant allowed patients to maintain good QoL in the endocrine resistance setting while experiencing

  5. Installation restoration program (irp) remedial investigation/feasibility study, Kotzebue Long Range Radar Station, Alaska. Human health and ecological risk assessment. Final baseline report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-07-01

    The purpose of the Baseline Human Health and Ecological Risk Assessment Report is to provide an assessment of the risk to human and ecological receptors from exposure to contaminants measured during the 1994 Remedial Investigation at Kotzebue Long Range Radar Station, Alaska.

  6. Combining short- and long-range fluorescence reporters with simulations to explore the intramolecular dynamics of an intrinsically disordered protein

    Science.gov (United States)

    Zosel, Franziska; Haenni, Dominik; Soranno, Andrea; Nettels, Daniel; Schuler, Benjamin

    2017-10-01

    Intrinsically disordered proteins (IDPs) are increasingly recognized as a class of molecules that can exert essential biological functions even in the absence of a well-defined three-dimensional structure. Understanding the conformational distributions and dynamics of these highly flexible proteins is thus essential for explaining the molecular mechanisms underlying their function. Single-molecule fluorescence spectroscopy in combination with Förster resonance energy transfer (FRET) is a powerful tool for probing intramolecular distances and the rapid long-range distance dynamics in IDPs. To complement the information from FRET, we combine it with photoinduced electron transfer (PET) quenching to monitor local loop-closure kinetics at the same time and in the same molecule. Here we employed this combination to investigate the intrinsically disordered N-terminal domain of HIV-1 integrase. The results show that both long-range dynamics and loop closure kinetics on the sub-microsecond time scale can be obtained reliably from a single set of measurements by the analysis with a comprehensive model of the underlying photon statistics including both FRET and PET. A more detailed molecular interpretation of the results is enabled by direct comparison with a recent extensive atomistic molecular dynamics simulation of integrase. The simulations are in good agreement with experiment and can explain the deviation from simple models of chain dynamics by the formation of persistent local secondary structure. The results illustrate the power of a close combination of single-molecule spectroscopy and simulations for advancing our understanding of the dynamics and detailed mechanisms in unfolded and intrinsically disordered proteins.

  7. Large Bowel Obstruction Caused by Adhesions without Previous ...

    African Journals Online (AJOL)

    Background: Large bowel obstruction is rarely caused by adhesions. To our knowledge, the few cases reported in literature are secondary to previous abdomino-pelvic surgery, and are in female patients. Case Reports: We report two cases of large bowel obstruction due to adhesions in males with no previous abdominal ...

  8. Closure Report for Corrective Action Unit 428: Area 3 Septic Waste Systems 1 and 5 Tonopah Test Range, Nevada

    Energy Technology Data Exchange (ETDEWEB)

    D. H. Cox

    2001-06-01

    The following site closure activities were performed at the CAU 428 site located at the TTR and are documented in this report: Preplanning and site preparation; Excavating and removing impacted soil; Removing septic tank contents; Closing septic tanks by filling them with clean soil; Collecting verification samples to verify that COCs have been removed to approved levels; Backfilling the excavations to surface grade with clean soil; Disposal of excavated materials following applicable federal, state, and DOE/NV regulations in accordance with Section 2.3 of the CAP (DOE/NV, 2000); and Decontamination of equipment as necessary. Closure was accomplished following the approved CAP (DOE/NV, 2000). Verification sample data demonstrate that all COCs were removed to the remediation standards. Therefore, the site is clean-closed.

  9. Assessment of Re-sighting Rates of Previously Dart-Tagged False Killer Whales and Short-Finned Pilot Whales in Hawai’i: A Preliminary Report Taking into Account Re-sighting of Social Groups

    Science.gov (United States)

    2011-10-14

    PSRG-2011-18   1  Assessment of re-sighting rates of previously dart-tagged false killer whales and short- finned pilot whales in Hawai‘i: a...98501 2Wild Whale Research Foundation, Box 139, Holualoa, HI 96725 3NOAA Southeast Fisheries Science Center, 101 Pivers Island Road, Beaufort, NC...Research, we are conducting follow-up studies on tagged whales to assess the effects of tagging on survival and reproduction. These studies are

  10. Range profiles of low energy (100 to 1500 eV) implanted /sup 3/He and /sup 4/He in tungsten. II. Analysis and discussion. Materials Science Center Report No. 4108

    Energy Technology Data Exchange (ETDEWEB)

    Amano, J; Wagner, A; Seidman, D N

    1980-08-01

    The identifiable sources of possible systematic error in the measurement of the mean range (x bar) and the straggling (..delta..x) of the /sup 3/He and /sup 4/He range profiles, reported on in a previous paper were modeled mathematically and the resulting expressions numerically evaluated. The evaluations showed that these possible sources of systematic error were not of significant magnitude to affect the range parameters x bar and ..delta..x. The role of the transfer of energy, either indirectly or directly, from the incoming beam of He ions to those He atoms that had already been implanted was also considered as a possible source of systematic error. It was shown that there was a possibility of radiation-induced diffusion or the simple collisional displacement of He atoms at an implantation energy of 100 eV and a dose of 4 x 10/sup 15/ cm/sup -2/. It was also demonstrated that for the sample sizes employed in the experimental work (Part I) the integral profiles were characterized with a reasonable degree of statistical significance. The experimental results presented in Part I were compared with the calculated results of Biersack's and Haggmark's TRIM simulation program. There was qualitative agreement between the experimental and calculated values of the range parameters but not quantitative. In general, the experimental values of the dimensionless range parameters were greater then the calculated values. The possible sources of this discrepancy were attributed to: the use of the Moliere interatomic potential in the TRIM program; and possible low-energy channeling effects along the (110) direction of W. Simple expressions were given for the experimental range-energy data and the effective stopping powers of both /sup 3/He and /sup 4/He in W in the energy range 100 to 1500 eV.

  11. A case report of percutaneous endoscopic gastrostomy left-side gastropexy to resolve a recurrent gastric dilatation in a dog previously treated with right-side gastropexy for gastric dilatation volvulus.

    Science.gov (United States)

    Spinella, Giuseppe; Cinti, Filippo; Pietra, Marco; Capitani, Ombretta; Valentini, Simona

    2014-12-01

    A 6-year-old, large-breed, female dog was evaluated for gastric dilatation (GD). The dog was affected by GD volvulus, which had been surgically treated with gastric derotation and right incisional gastropexy. Recurrence of GD appeared 36 hours after surgery. The dilatation was immediately treated with an orogastric probe but still recurred 4 times. Therefore, a left-side gastropexy by percutaneous endoscopic gastrostomy (PEG) was performed to prevent intermittent GD. After PEG tube placement, the patient recovered rapidly without side effects. Several techniques of gastropexy have been described as a prophylactic method for gastric dilatation volvulus, but to the authors' knowledge, this is the first report of left-sided PEG gastropexy performed in a case of canine GD recurrence after an incisional right gastropexy. Copyright © 2015 Elsevier Inc. All rights reserved.

  12. Use of a novel cell-based fusion reporter assay to explore the host range of human respiratory syncytial virus F protein

    Directory of Open Access Journals (Sweden)

    Sarisky Robert T

    2005-07-01

    Full Text Available Abstract Human respiratory syncytial virus (HRSV is an important respiratory pathogen primarily affecting infants, young children, transplant recipients and the elderly. The F protein is the only virion envelope protein necessary and sufficient for virus replication and fusion of the viral envelope membrane with the target host cell. During natural infection, HRSV replication is limited to respiratory epithelial cells with disseminated infection rarely, if ever, occurring even in immunocompromised patients. However, in vitro infection of multiple human and non-human cell types other than those of pulmonary tract origin has been reported. To better define host cell surface molecules that mediate viral entry and dissect the factors controlling permissivity for HRSV, we explored the host range of HRSV F protein mediated fusion. Using a novel recombinant reporter gene based fusion assay, HRSV F protein was shown to mediate fusion with cells derived from a wide range of vertebrate species including human, feline, equine, canine, bat, rodent, avian, porcine and even amphibian (Xenopus. That finding was extended using a recombinant HRSV engineered to express green fluorescent protein (GFP, to confirm that viral mRNA expression is limited in several cell types. These findings suggest that HRSV F protein interacts with either highly conserved host cell surface molecules or can use multiple mechanisms to enter cells, and that the primary determinants of HRSV host range are at steps post-entry.

  13. Post-Closure Inspection Report for Corrective Action Unit 426: Cactus Spring Waste Trenches Tonopah Test Range, Nevada Calendar Year 2000

    Energy Technology Data Exchange (ETDEWEB)

    K. B. Campbell

    2001-06-01

    Post-closure monitoring requirements for the Cactus Spring Waste Trenches (Corrective Action Unit [CAW 426]) (Figure 1) are described in Closure Report for corrective Action Unit 426, Cactus Spring Waste Trenches. Tonopah Test Range, Nevada, report number DOE/NV--226. The Closure Report (CR) was submitted to the Nevada Division of Environmental Protection (NDEP) on August 14, 1998. Permeability results of soils adjacent to the engineered cover and a request for closure of CAU 404 were transmitted to the NDEP on April 29, 1999. The CR (containing the Post-Closure Monitoring Plan) was approved by the NDEP on May 13, 1999. Post-closure monitoring at CAU 426 consists of the following: (1) Site inspections done twice a year to evaluate the condition of the unit; (2) Verification that the site is secure; (3) Notice of any subsidence or deficiencies that may compromise the integrity of the unit; (4) Remedy of any deficiencies within 90 days of discovery; and (5) Preparation and submittal of an annual report. Site inspections were conducted on June 19, 2000, and November 21, 2000. All inspections were made after NDEP approval of the CR, and were conducted in accordance with the Post-Closure Monitoring Plan in the NDEP-approved CR. This report includes copies of the inspection checklists, photographs, recommendations, and conclusions. The Post-Closure Inspection Checklists are found in Attachment A, a copy of the field notes is found in Attachment B, and copies of the inspection photographs are found in Attachment C.

  14. Regional Operations Research Program for Commercialization of Geothermal Energy in the Rocky Mountain Basin and Range. Final Technical Report, January 1980--March 1981

    Energy Technology Data Exchange (ETDEWEB)

    None

    1981-07-01

    This report describes the work accomplished from January 1980 to March 1981 in the Regional Operations Research efforts for the Rocky Mountain Basin and Range Geothermal Commercialization Program. The scope of work is as described in New Mexico State University Proposal 80-20-207. The work included continued data acquisition and extension of the data base, enhancement and refinement of the economic models for electric and direct use applications, site-specific and aggregated analyses in support of the state teams, special analyses in support of several federal agencies, and marketing assistance to the state commercialization teams.

  15. Corrective Action Decision Document/Closure Report for Corrective Action Unit 410: Waste Disposal Trenches, Tonopah Test Range, Nevada: Revision No. 0

    Energy Technology Data Exchange (ETDEWEB)

    U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office

    2003-12-22

    This Corrective Action Decision Document/Closure Report (CADD/CR) has been prepared for Corrective Action Unit (CAU) 410: Waste Disposal Trenches, Tonopah Test Range, Nevada, in accordance with the Federal Facility Agreement and Consent Order. Corrective Action Unit 410 consists of five Corrective Action Sites (CASs): TA-21-003-TANL; 09-21-001-TA09; TA-19-002-TAB2; TA-21-002-TAAL; and 03-19-001. The CADD and CR have been combined into one report because no further action is recommended for this CAU. The corrective action alternative recommended for CAU 410 is Clean Closure; therefore, no corrective action or corrective action plan is required. No use restrictions are required to be placed on this CAU because the investigation showed no evidence of remaining soil contamination or remaining debris/waste upon completion of all investigation activities.

  16. Melanoma diagnosed in lesions previously treated by laser therapy.

    Science.gov (United States)

    Delker, Sarah; Livingstone, Elisabeth; Schimming, Tobias; Schadendorf, Dirk; Griewank, Klaus G

    2017-01-01

    Laser therapy has become a routine procedure in dermatological practice and is frequently also used for pigmented lesions. Few reports exist of melanomas diagnosed in lesions previously treated by laser therapy. Between 2007 and 2014, we identified 11 patients who presented to our department with a melanoma diagnosed in a region previously treated by laser therapy. The course of events until the diagnosis of melanoma was assessed as well as patient outcome including treatment for disease progression. No histological assessment had been performed prior to laser therapy in nine of 11 (82%) cases. Benign melanocytic lesions had been diagnosed by biopsy prior to laser therapy in the other two cases. Time from laser therapy to diagnosis of melanoma ranged from less than 1 to 10 years. Stage of disease at diagnosis varied from stage IA to IIIC. Four patients progressed to stage IV disease, of whom at least one died of melanoma. We conclude that laser treatment of pigmented lesions can complicate the diagnosis of melanoma and lead to diagnosis delay with potentially fatal consequences. Considering this risk, we believe laser therapy for pigmented lesions should either be avoided entirely or at a minimum performed only after prior histological assessment. © 2016 Japanese Dermatological Association.

  17. Does previous healthcare experience increase success in physician assistant training?

    Science.gov (United States)

    Hegmann, Theresa; Iverson, Katie

    2016-06-01

    Healthcare experience is used by many physician assistant (PA) programs to rank applicants. Despite a large healthcare literature base evaluating admissions factors, little information is available on the relationship of healthcare experience and educational outcomes. We aimed to test whether previous healthcare experience is associated with increased success during the clinical portion of the PA educational process. Hours of direct healthcare experience reported on Central Application Service for Physician Assistants applications for 124 students in the classes of 2009 through 2013 were associated with a calculated average preceptor evaluation score for each student and with average standardized-patient examination scores for a subset of students. Average student age was 28.7 years and median healthcare experience was 2,257 hours (range 390-16,400). Previous healthcare experience was not significantly correlated with preceptor evaluations or standardized-patient examination scores. This 5-year single institution pilot study did not support the hypothesis that healthcare experience is associated with improved clinical year outcomes.

  18. Medium-Range Order in Amorphous Silicon Measured by Fluctuation Electron Microscopy: Final Report, 23 June 1999--23 August 2002

    Energy Technology Data Exchange (ETDEWEB)

    Voyles, P. M.; Abelson, J. R.

    2003-10-01

    Despite occasional experimental hints, medium-range structural order in covalently bonded amorphous semiconductors had largely escaped detection until the advent of fluctuation electron microscopy (FEM) in 1996. Using FEM, we find that every sample of amorphous silicon and germanium we have investigated, regardless of deposition method or hydrogen content, is rich in medium-range order. The paracrystalline structural model, which consists of small, topologically ordered grains in an amorphous matrix, is consistent with the FEM data; but due to strain effects, materials with a paracrystalline structure appear to be amorphous in diffraction measurements. We present measurements on hydrogenated amorphous silicon deposited by different methods, some of which are reported to have greater stability against the Staebler-Wronski effect. FEM reveals that the matrix material of these samples is relatively similar, but the order changes in different ways upon both light soaking and thermal annealing. Some materials are inhomogeneous, with either nanocrystalline inclusions or large area-to-area variation in the medium-range order. We cite recent calculations that electronic states in the conduction band tail are preferentially located around the boundaries of the nm-scale paracrystalline regions that we have identified. This is new evidence in support of spatially inhomogeneous conduction mechanisms in a-Si. The key discovery in our work is that all samples of amorphous silicon must be described as having nm-scale topological crystalline order. This strongly modifies the long-standing model of a covalent random network. Our new understanding of medium-range order must be considered in all future models of electronic properties and the Staebler-Wronski effect.

  19. 7th annual report 1998. UN ECE convention on long-range transboundary air pollution. International cooperative programme on integrated monitoring of air pollution effects on ecosystems

    Energy Technology Data Exchange (ETDEWEB)

    Kleemola, S.; Forsius, M. [eds.

    1998-11-01

    The Integrated Monitoring Programme (ICP IM) is part of the Effects Monitoring Strategy under the UN ECE Long-Range Transboundary Air Pollution Convention. The main aim of ICP IM is to provide a framework to observe and understand the complex changes occurring in the external environment. The monitoring and prediction of complex ecosystem effects on undisturbed reference areas require a continuous effort to improve the collection and assessment of data on the international scale. At the 1997 Task Force meeting it was decided that future annual reports from ICP IM would have a more technical character. The report could include some scientific material but also short technical descriptions of recent national activities and publications. Scientific articles should preferably be published in recognised scientific journals. The responsibility for producing annual reports would still lie on the Programme Centre, but more contributions from National Focal Points were welcomed. The content of the present Annual Report reflects the decisions of the Task Force meeting. The report gives a general overview of the ICP IM activities, the present content of the ICP IM database, and presents results from assessment activities carried out by several collaborating institutes and the ICP IM Programme Centre during the programme year 1997/98. The resources of the Programme Centre have been targeted to the revision of the Programme Manual and the EU/LIFE-project `Development of Assessment and Monitoring Techniques at Integrated Monitoring Sites in Europe`, which has limited the possibilities to carry out additional evaluations of ICP IM data. Section 1 is a short status report of the ICP IM activities, content of the IM database, including the contents of the GIS database, and the present geographical coverage of the monitoring network. Section 2 contains a report on multivariate gradient analysis applied to relate chemical and biological observations (prepared by D. de Zwart, RIVM

  20. Post-Closure Inspection Report for Corrective Action Unit 404: Roller Coaster Sewage Lagoons and North Disposal Trench Tonopah Test Range, Nevada, Calendar Year 2000

    Energy Technology Data Exchange (ETDEWEB)

    K. B. Campbell

    2001-06-01

    Post-closure monitoring requirements for the Roller Coaster Sewage Lagoons and North Disposal Trench (Corrective Action Unit [CAW 404]) (Figure 1) are described in Closure Report for Corrective Action Unit 404, Roller Coaster Sewage Lagoons and North Disposal Trench, Tonopah Test Range, Nevada, report number DOE/NV--187. The Closure Report (CR) was submitted to the Nevada Division of Environmental Protection (NDEP) on September 11, 1998. Permeability results of soils adjacent to the engineered cover and a request for closure of CAU 404 were transmitted to the NDEP on April 29, 1999. The CR (containing the Post-Closure Monitoring Plan) was approved by the NDEP on May 18, 1999. Post-closure monitoring at CAU 404 consists of the following: (1) Site inspections done twice a year to evaluate the condition of the unit; (2) Verification that the site is secure; (3) Notice of any subsidence or deficiencies that may compromise the integrity of the unit; (4) Remedy of any deficiencies within 90 days of discovery; and (5) Preparation and submittal of an annual report. Site inspections were conducted on June 19, 2000, and November 21, 2000. The site inspections were conducted after completion of the revegetation activities (October 30, 1997) and NDEP approval of the CR (May 18, 1999). All site inspections were conducted in accordance with the Post-Closure Monitoring Plan in the NDEP-approved CR. This report includes copies of inspection checklists, photographs, recommendations, and conclusions. The Post-Closure Inspection Checklists are found in Attachment A, a copy of the field notes is found in Attachment B, and copies of the inspection photographs are found in Attachment C.

  1. Disability progression in multiple sclerosis is slower than previously reported.

    Science.gov (United States)

    Tremlett, Helen; Paty, Donald; Devonshire, Virginia

    2006-01-24

    To investigate disease progression and risk factors in a large geographically based population with multiple sclerosis (MS), using two different inception points--clinical onset and date of birth. The authors reviewed a database of subjects with definite MS and symptom onset prior to July 1988. The main outcome was sustained progression to Expanded Disability Status Scale (EDSS) 6 (requires a cane), using the date of birth and date of MS onset as inception points in separate analyses. Risk factors examined were sex, relapsing vs primary progressive course, onset age, and onset symptoms. The study included 2,837 patients, followed prospectively for 22,723 patient years. The median time to EDSS 6 was 27.9 years, 15 years after onset; only 21% reached EDSS 6, and by age 50, 28% required a cane. Men progressed 38% more quickly than women from onset (p men and 60.1 for women (p = 0.082). A younger onset age predicted a slower progression, but those older at onset were consistently older when reaching EDSS 6. A primary progressive course predicted a more rapid progression from both onset (p multiple sclerosis (MS) accrued more slowly than found in earlier longitudinal studies. The authors also challenged two fundamental concepts in MS, demonstrating that neither male sex nor older onset age was associated with worse disease outcome.

  2. Production of Short-Rotation Woody Crops Grown with a Range of Nutrient and Water Availability: Establishment Report and First-Year Responses

    Energy Technology Data Exchange (ETDEWEB)

    D.R. Coyle; J. Blake; K. Britton; M.; R.G. Campbell; J. Cox; B. Cregg; D. Daniels; M. Jacobson; K. Johnsen; T. McDonald; K. McLeod; E.; D. Robison; R. Rummer; F. Sanchez; J.; B. Stokes; C. Trettin; J. Tuskan; L. Wright; S. Wullschleger

    2003-12-31

    Coleman, M.D., et. al. 2003. Production of Short-Rotation Woody Crops Grown with a Range of Nutrient and Water Availability: Establishment Report and First-Year Responses. Report. USDA Forest Service, Savannah River, Aiken, SC. 26 pp. Abstract: Many researchers have studied the productivity potential of intensively managed forest plantations. However, we need to learn more about the effects of fundamental growth processes on forest productivity; especially the influence of aboveground and belowground resource acquisition and allocation. This report presents installation, establishment, and first-year results of four tree species (two cottonwood clones, sycamore, sweetgum, and loblolly pine) grown with fertilizer and irrigation treatments. At this early stage of development, irrigation and fertilization were additive only in cottonwood clone ST66 and sweetgum. Leaf area development was directly related to stem growth, but root production was not always consistent with shoot responses, suggesting that allocation of resources varies among treatments. We will evaluate the consequences of these early responses on resource availability in subsequent growing seasons. This information will be used to: (1) optimize fiber and bioenergy production; (2) understand carbon sequestration; and (3) develop innovative applications such as phytoremediation; municipal, industrial, and agricultural wastes management; and protection of soil, air, and water resources.

  3. Closure Report for Corrective Action Unit 404: Roller Coaster Sewage Lagoons and North Disposal Trench, Tonopah Test Range, Nevada with ROTC 1, Revision 0

    Energy Technology Data Exchange (ETDEWEB)

    Lynn Kidman

    1998-09-01

    This Closure Report provides the documentation for closure of the Roller Coaster Sewage Lagoons and North Disposal Trench Comective Action Unit (CAU) 404. CAU 404 consists of the Roller Coaster Sewage Lagoons (Corrective Action Site [CAS] TA-03-O01-TA-RC) and the North Disposal Trench (CAS TA-21-001-TA-RC). The site is located on the Tonopah Test Range, approximately 225 kilometers (km) (140 miles [mi]) northwest ofLas Vegas, Nevada. . The sewage lagoons received ~quid sanitary waste horn the Operation Roller Coaster Man Camp in 1963 and debris from subsequent range and construction cleanup activities. The debris and ordnance was subsequently removed and properly dispos~, however, pesticides were detected in soil samples born the bottom of the lagoons above the U,S. Environmental Protection Agency Region IX Prelimimuy Remediation Goals (EPA 1996). . The North Disposal Trench was excavated in 1963. Debris from the man camp and subsequent range and construction cleanup activities was placed in the trench. Investigation results indicated that no constituents of concern were detected in soil samples collected from the trench. Remedial alternative proposed in the Comctive Action Decision Document (CADD) fm the site was “Covering” (DOE, 1997a). The Nevada Division of”Enviromnental Protection (NDEP)-approved Correction Action Plan (CAP) proposed the “Covering” niethodology (1997b). The closure activities were completed in accorhce with the approwil CAP and consisted of baclctllling the sewage lagoons and disposal trench, constructing/planting an engineered/vegetative cover in the area of the sewage lagoons and dikposal trencQ installing a perimeter fence and signs, implementing restrictions on fi~e use, and preparing a Post-Closure Monitoring Plan. “ Since closure activities. for CAU 404 have been completed in accordance with the Nevada Division of Environmental Protection-approved CAP (DOE, 1997b) as documented in this Closure Report, the U.S. Department of

  4. 77 FR 70176 - Previous Participation Certification

    Science.gov (United States)

    2012-11-23

    ... URBAN DEVELOPMENT Previous Participation Certification AGENCY: Office of the Chief Information Officer... digital submission of all data and certifications is available via HUD's secure Internet systems. However...: Previous Participation Certification. OMB Approval Number: 2502-0118. Form Numbers: HUD-2530 . Description...

  5. Corrective Action Decision Document/Closure Report for Corrective Action 405: Area 3 Septic Systems, Tonopah Test Range, Nevada Rev. No.: 0, April 2002

    Energy Technology Data Exchange (ETDEWEB)

    IT Coroporation, Las Vegas, NV

    2002-04-17

    This Corrective Action Decision Document/Closure Report (CADD/CR) has been prepared for Corrective Action Unit (CAU) 405, Area 3 Septic Systems, in accordance with the Federal Facility Agreement and Consent Order. Located on the Tonopah Test Range (TTR) approximately 235 miles north of Las Vegas, Nevada, CAU 405 consists of three Corrective Action Sites (CASs): 03-05-002-SW03, Septic Waste System (aka: Septic Waste System [SWS] 3); 03-05-002-SW04, Septic Waste System (aka: SWS 4); 03-05-002-SW07, Septic Waste System (aka: SWS 7). The CADD and CR have been combined into one report because no further action is recommended for this CAU, and this report provides specific information necessary to support this recommendation. The CAU consists of three leachfields and associated collection systems that were installed in or near Area 3 for wastewater disposal. These systems were used until a consolidated sewer system was installed in 1990. Historically, operations within various buildin gs in and near Area 3 of the TTR generated sanitary and industrial wastewaters. There is a potential that contaminants of concern (COCs) were present in the wastewaters and were disposed of in septic tanks and leachfields. The justification for closure of this CAU without further action is based on process knowledge and the results of the investigative activities. Closure activities were performed at these CASs between January 14 and February 2, 2002, and included the removal and proper disposal of media containing regulated constituents and proper closure of septic tanks. No further action is appropriate because all necessary activities have been completed. No use restrictions are required to be imposed for these sites since the investigation showed no evidence of COCs identified in the soil for CAU 405.

  6. Ranging Behaviour of Commercial Free-Range Laying Hens

    Science.gov (United States)

    Chielo, Leonard Ikenna; Pike, Tom; Cooper, Jonathan

    2016-01-01

    Simple Summary Commercial free-range production has become a significant sector of the fresh egg market due to legislation banning conventional cages and consumer preference for products perceived as welfare friendly, as access to outdoor range can lead to welfare benefits such as greater freedom of movement and enhanced behavioural opportunities. This study investigated dispersal patterns, feather condition and activity of laying hens in three distinct zones of the range area; the apron area near shed; enriched zone 10–50 m from shed; and outer range beyond 50 m, in six flocks of laying hens under commercial free-range conditions varying in size between 4000 and 24,000 hens. Each flock was visited for four days to record number of hens in each zone, their behaviour, feather condition and nearest neighbour distances (NND), as well as record temperature and relative humidity during the visit. Temperature and relative humidity varied across the study period in line with seasonal variations and influenced the use of range with fewer hens out of shed as temperature fell or relative humidity rose. On average, 12.5% of the hens were observed on the range and most of these hens were recorded in the apron zone as hen density decreased rapidly with increasing distance from the shed. Larger flocks appeared to have a lower proportion of hens on range. The hens used the range more in the early morning followed by a progressive decrease through to early afternoon. The NND was greatest in the outer range and decreased towards the shed. Feather condition was generally good and hens observed in the outer range had the best overall feather condition. Standing, pecking, walking and foraging were the most commonly recorded behaviours and of these, standing occurred most in the apron whereas walking and foraging behaviours were recorded most in the outer range. This study supported the findings of previous studies that reported few hens in the range and greater use of areas closer

  7. 2016 Annual Site Environmental report Sandia National Laboratories Tonopah Test Range Nevada & Kaua'i Test Facility Hawai'i.

    Energy Technology Data Exchange (ETDEWEB)

    Salas, Angela Maria [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Griffith, Stacy R. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-07-01

    Sandia National Laboratories (SNL) is a multimission laboratory managed and operated by National Technology & Engineering Solutions of Sandia, LLC, a wholly owned subsidiary of Honeywell International Inc., for the U.S. Department of Energy’s (DOE’s), National Nuclear Security Administration (NNSA) under contract DE-NA0003525. The DOE/NNSA Sandia Field Office administers the contract and oversees contractor operations at the SNL, Tonopah Test Range (SNL/TTR) in Nevada and the SNL, Kaua‘i Test Facility (SNL/KTF) in Hawai‘i. SNL personnel manage and conduct operations at SNL/TTR in support of the DOE/NNSA’s Weapons Ordnance Program and have operated the site since 1957. Navarro Research and Engineering personnel perform most of the environmental programs activities at SNL/TTR. The DOE/NNSA/Nevada Field Office retains responsibility for cleanup and management of SNL/TTR Environmental Restoration sites. SNL personnel operate SNL/KTF as a rocket preparation launching and tracking facility. This Annual Site Environmental Report (ASER) summarizes data and the compliance status of sustainability, environmental protection, and monitoring programs at SNL/TTR and SNL/KTF during calendar year 2016. Major environmental programs include air quality, water quality, groundwater protection, terrestrial and biological surveillance, waste management, pollution prevention, environmental restoration, oil and chemical spill prevention, and implementation of the National Environmental Policy Act. This ASER is prepared in accordance with and as required by DOE O 231.1B, Admin Change 1, Environment, Safety, and Health Reporting.

  8. 6th Annual Report 1997. UN ECE convention on long-range transboundary air pollution. International cooperative programme on integrated monitoring of air pollution effects on ecosystems

    Energy Technology Data Exchange (ETDEWEB)

    Kleemola, S.; Forsius, M. [eds.

    1997-12-31

    The Integrated Monitoring Programme (IC P IM) is part of the Effects Monitoring Strategy under the UN ECE Convention on Long-Range Transboundary Air Pollution. The main aim of ICP IM is to provide a framework to observe and understand the complex changes occurring in the external environment. The monitoring and prediction of complex ecosystem effects on undisturbed reference areas require a continuous effort to improve the collection and assessment of data on the international scale. This report presents results from assessment activities carried out by the ICP IM Programme Centre and collaborating institutes during the programme year 1996/97 including (1) a summary of the present monitoring activities and the content of the ICP IM database as well as a description of the development of a GIS database, (2) comparison and assessment of the use of steady-state techniques vs. dynamic modelling for the calculation of critical loads, (3) results from a trend analysis of ICP IM data on bulk and throughfall deposition ant runoff water chemistry, (4) demonstration of the use of ICP IM data for advanced hydrological modelling (SVAT model). (orig.) 10 refs.

  9. Empowerment perceptions of educational managers from previously ...

    African Journals Online (AJOL)

    The perceptions of educational manag ers from previously disadvantaged primary and high schools in the Nelson Mandela Metropole regarding the issue of empowerment are outlined and the perceptions of educational managers in terms of various aspects of empowerment at different levels reflected. A literature study ...

  10. Knowledge and Previous Contraceptive Use by Pregnant ...

    African Journals Online (AJOL)

    Information obtained included demographic characteristics, knowledge of and previous use of contraception. Results: Respondents displayed a high level of contraceptive knowledge, as 277 (91.7%) were aware of it. The condom and the combined oral pill were the two contraceptive methods most commonly known, by 254 ...

  11. Subsequent pregnancy outcome after previous foetal death

    NARCIS (Netherlands)

    Nijkamp, J. W.; Korteweg, F. J.; Holm, J. P.; Timmer, A.; Erwich, J. J. H. M.; van Pampus, M. G.

    Objective: A history of foetal death is a risk factor for complications and foetal death in subsequent pregnancies as most previous risk factors remain present and an underlying cause of death may recur. The purpose of this study was to evaluate subsequent pregnancy outcome after foetal death and to

  12. Laboratory Grouping Based on Previous Courses.

    Science.gov (United States)

    Doemling, Donald B.; Bowman, Douglas C.

    1981-01-01

    In a five-year study, second-year human physiology students were grouped for laboratory according to previous physiology and laboratory experience. No significant differences in course or board examination performance were found, though correlations were found between predental grade-point averages and grouping. (MSE)

  13. Geology and geothermal resources of the Santiam Pass area of the Oregon Cascade Range, Deschutes, Jefferson and Linn Counties, Oregon. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Hill, B.E. [ed.

    1992-10-01

    This open-file report presents the results of the Santiam Pass drilling program. The first phase of this program was to compile all available geological, geophysical and geothermal data for the Santiam Pass area and select a drill site on the basis of these data (see Priest and others, 1987a), A summary of the drilling operations and costs associated with the project are presented in chapter 1 by Hill and Benoit. An Overview of the geology of the Santiam Pass area is presented by Hill and Priest in chapter 2. Geologic mapping and isotopic age determinations in the Santiam Pass-Mount Jefferson area completed since 1987 are summarized in chapter 2. One of the more important conclusions reached in chapter 2 is that a minimum of 2 km vertical displacement has occurred in the High Cascade graben in the Santiam Pass area. The petrology of the Santiam Pass drill core is presented by Hill in chapter 3. Most of the major volcanic units in the core have been analyzed for major, minor, and trace element abundances and have been studied petrographically. Three K-Ar ages are interpreted in conjunction with the magnetostratigraphy of the core to show that the oldest rocks in the core are approximately 1.8 Ma. Geothermal and geophysical data collected from the Santiam Pass well are presented by Blackwell in chapter 4. The Santiam Pass well failed to penetrate beneath the zone of lateral groundwater flow associated with highly permeable Quaternary volcanic rocks. Calculated geothermal gradients range from about 50{degree}C/km at depth 700-900 m, to roughly 110{degree}C/km from 900 m to the bottom of the well at 929 m. Heat-flow values for the bottom part of the hole bracket the regional average for the High Cascades. Blackwell concludes that heat flow along the High Cascades axis is equal to or higher than along the western edge of the High Cascades.

  14. Ranging Behaviour of Commercial Free-Range Broiler Chickens 1: Factors Related to Flock Variability.

    Science.gov (United States)

    Taylor, Peta S; Hemsworth, Paul H; Groves, Peter J; Gebhardt-Henrich, Sabine G; Rault, Jean-Loup

    2017-07-20

    Little is known about the ranging behaviour of chickens. Understanding ranging behaviour is required to improve management and shed and range design to ensure optimal ranging opportunities. Using Radio Frequency Identification technology, we tracked 300 individual broiler chickens in each of four mixed sex ROSS 308 flocks on one commercial farm across two seasons. Ranging behaviour was tracked from the first day of range access (21 days of age) until 35 days of age in winter and 44 days of age in summer. Range use was higher than previously reported from scan sampling studies. More chickens accessed the range in summer (81%) than winter (32%; p < 0.05). On average, daily frequency and duration of range use was greater in summer flocks (4.4 ± 0.1 visits for a total of 26.3 ± 0.8 min/day) than winter flocks (3.2 ± 0.2 visits for a total of 7.9 ± 1.0 min/day). Seasonal differences were only marginally explained by weather conditions and may reflect the reduction in range exposure between seasons (number of days, hours per day, and time of day). Specific times of the day (p < 0.01) and pop-holes were favoured (p < 0.05). We provide evidence of relationships between ranging and external factors that may explain ranging preferences.

  15. Previously undiagnosed hemophilia patient with intracerebral hemorrhage

    Directory of Open Access Journals (Sweden)

    Eray Atalay

    2015-09-01

    Full Text Available Intracranial bleeding in hemophilia patients is a rare but a mortal complication. Diagnosis of hemophilia in adulthood is an uncommon occurrence. In this case report an adult patient with intracranial hemorrhage is presented.

  16. Narrative report 1969: Charles M. Russell National Wildlife Range and Hailstone, Halfbreed, Mason, Yellow Water, War Horse & Wild Horse National Wildlife Refuges

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This annual narrative report for Charles M. Russell NWR (including the satellite refuges) outlines Refuge accomplishments during the 1969 calendar year. The report...

  17. Narrative report 1968: Charles M. Russell National Wildlife Range and Hailstone*, Halfbreed*, Mason*, Miller*, Yellow Water*, War Horse*, & Wild Horse* National Wildlife Refuges

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This annual narrative report for Charles M. Russell NWR (including the satellite refuges) outlines Refuge accomplishments during the 1968 calendar year. The report...

  18. Narrative report 1972: Charles M. Russell National Wildlife Range and Hailstone, Halfbreed, Lake Mason, Yellow Water, War Horse, & Wild Horse Wildlife Refuges

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This annual narrative report for Charles M. Russell NWR (including the satellite refuges) outlines Refuge accomplishments during the 1972 calendar year. The report...

  19. Haemophilus influenzae type f meningitis in a previously healthy boy

    DEFF Research Database (Denmark)

    Ronit, Andreas; Berg, Ronan M G; Bruunsgaard, Helle

    2013-01-01

    Non-serotype b strains of Haemophilus influenzae are extremely rare causes of acute bacterial meningitis in immunocompetent individuals. We report a case of acute bacterial meningitis in a 14-year-old boy, who was previously healthy and had been immunised against H influenzae serotype b (Hib...

  20. Final quality assurance project plan, installation restoration program remedial investigation/feasibility study, Kotzebue Long Range Radar Station, Alaska. Volume 1. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-10-01

    This quality assurance project plan describes relevant quality assurance/quality control (QA/QC) procedures to be used by Analytical Resources, Inc. for the installation restoration program at Kotzebue Long Range Radar Station, Alaska.

  1. Final quality assurance project plan, installation restoration program remedial investigation/feasibility study, Kotzebue Long Range Radar Station, Alaska. Volume 2. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-10-01

    This quality assurance project plan describes relevant quality assurance/quality control (QA/QC) procedures to be used by Analytical Resources, Inc. for the installation restoration program at Kotzebue Long Range Radar Station, Alaska.

  2. Anisometropia magnitude and visual deficits in previously untreated anisometropic amblyopia

    Directory of Open Access Journals (Sweden)

    Bin-Bin Chen

    2013-10-01

    Full Text Available AIM:To assess the quantitative association between anisometropia magnitude and the losses of resolution and contrast sensitivity; and to exemplify how the function of fusion and stereopsis vary with anisometropia magnitude (AM in previously untreated anisometropic amblyopes.METHODS:A total of 57 patients with previously untreated anisometropic amblyopia without strabismus (range:8-35 years, were measured refractive error, best corrected visual acuity (BCVA, fusion and stereopsis, and 48 patients have completed contrast sensitivity function test. AM was determined by dioptric vector addition model, and the amblyopia depth was determined by the difference of BCVA in logMAR units between the amblyopic and fellow eyes.RESULTS: AM was significantly correlated with both amblyopia depth (Pearson R=0.728, PPPCONCLUSION: In the patients with previously untreated anisometropia amblyopia, higher degree of anisometropia is significantly associated with deeper amblyopia, worse contrast sensitivity, fusion and stereopsis functions.

  3. Intravitreal ranibizumab for diabetic macular oedema in previously vitrectomized eyes

    DEFF Research Database (Denmark)

    Laugesen, Caroline Schmidt; Ostri, Christoffer; Brynskov, Troels

    2017-01-01

    PURPOSE: There is little information about the efficacy of intravitreal vascular endothelial growth factor (VEGF) inhibition in vitrectomized eyes. This study aimed to evaluate the efficacy of anti-VEGF (ranibizumab) on diabetic macular oedema in previously vitrectomized eyes. METHODS: A nationwide...... retrospective review of medical records from 2010 to 2013. RESULTS: We identified 33 previously vitrectomized eyes in 28 patients treated with ranibizumab injections for diabetic macular oedema. Median follow-up was 323 days (interquartile range 72-1404 days). Baseline mean visual acuity was 0.57 logMAR (95% CI......). The mean reduction in CFT was 14% (95% CI 4-24%, p = 0.01). Sixteen eyes (48.5%) became devoid of oedema on the last OCT scan. Despite the significant reduction in CFT, the visual acuity remained unchanged. CONCLUSION: Intravitreal ranibizumab can be effective in previously vitrectomized eyes with diabetic...

  4. Books average previous decade of economic misery.

    Science.gov (United States)

    Bentley, R Alexander; Acerbi, Alberto; Ormerod, Paul; Lampos, Vasileios

    2014-01-01

    For the 20(th) century since the Depression, we find a strong correlation between a 'literary misery index' derived from English language books and a moving average of the previous decade of the annual U.S. economic misery index, which is the sum of inflation and unemployment rates. We find a peak in the goodness of fit at 11 years for the moving average. The fit between the two misery indices holds when using different techniques to measure the literary misery index, and this fit is significantly better than other possible correlations with different emotion indices. To check the robustness of the results, we also analysed books written in German language and obtained very similar correlations with the German economic misery index. The results suggest that millions of books published every year average the authors' shared economic experiences over the past decade.

  5. Induced vaginal birth after previous caesarean section

    Directory of Open Access Journals (Sweden)

    Akylbek Tussupkaliyev

    2016-11-01

    Full Text Available Introduction The rate of operative birth by Caesarean section is constantly rising. In Kazakhstan, it reaches 27 per cent. Research data confirm that the percentage of successful vaginal births after previous Caesarean section is 50–70 per cent. How safe the induction of vaginal birth after Caesarean (VBAC remains unclear. Methodology The studied techniques of labour induction were amniotomy of the foetal bladder with the vulsellum ramus, intravaginal administration of E1 prostaglandin (Misoprostol, and intravenous infusion of Oxytocin-Richter. The assessment of rediness of parturient canals was conducted by Bishop’s score; the labour course was assessed by a partogram. The effectiveness of labour induction techniques was assessed by the number of administered doses, the time of onset of regular labour, the course of labour and the postpartum period and the presence of complications, and the course of the early neonatal period, which implied the assessment of the child’s condition, described in the newborn development record. The foetus was assessed by medical ultrasound and antenatal and intranatal cardiotocography (CTG. Obtained results were analysed with SAS statistical processing software. Results The overall percentage of successful births with intravaginal administration of Misoprostol was 93 per cent (83 of cases. This percentage was higher than in the amniotomy group (relative risk (RR 11.7 and was similar to the oxytocin group (RR 0.83. Amniotomy was effective in 54 per cent (39 of cases, when it induced regular labour. Intravenous oxytocin infusion was effective in 94 per cent (89 of cases. This percentage was higher than that with amniotomy (RR 12.5. Conclusions The success of vaginal delivery after previous Caesarean section can be achieved in almost 70 per cent of cases. At that, labour induction does not decrease this indicator and remains within population boundaries.

  6. Previous Experience a Model of Practice UNAE

    OpenAIRE

    Ruiz, Ormary Barberi; Pesántez Palacios, María Dolores

    2017-01-01

    The statements presented in this article represents a preliminary version of the proposed model of pre-professional practices (PPP) of the National University of Education (UNAE) of Ecuador, an urgent institutional necessity is revealed in the descriptive analyzes conducted from technical support - administrative (reports, interviews, testimonials), pedagogical foundations of UNAE (curricular directionality, transverse axes in practice, career plan, approach and diagnostic examination as subj...

  7. Hypoparathyroidism after total thyroidectomy in patients with previous gastric bypass.

    Science.gov (United States)

    Droeser, Raoul A; Ottosson, Johan; Muth, Andreas; Hultin, Hella; Lindwall-Åhlander, Karin; Bergenfelz, Anders; Almquist, Martin

    2017-03-01

    Case reports suggest that patients with previous gastric bypass have an increased risk of severe hypocalcemia after total thyroidectomy, but there are no population-based studies. The prevalence of gastric bypass before thyroidectomy and the risk of hypocalcemia after thyroidectomy in patients with previous gastric bypass were investigated. By cross-linking The Scandinavian Quality Registry for Thyroid, Parathyroid and Adrenal Surgery with the Scandinavian Obesity Surgery Registry patients operated with total thyroidectomy without concurrent or previous surgery for hyperparathyroidism were identified and grouped according to previous gastric bypass. The risk of treatment with intravenous calcium during hospital stay, and with oral calcium and vitamin D at 6 weeks and 6 months postoperatively was calculated by using multiple logistic regression in the overall cohort and in a 1:1 nested case-control analysis. We identified 6115 patients treated with total thyroidectomy. Out of these, 25 (0.4 %) had undergone previous gastric bypass surgery. In logistic regression, previous gastric bypass was not associated with treatment with i.v. calcium (OR 2.05, 95 % CI 0.48-8.74), or calcium and/or vitamin D at 6 weeks (1.14 (0.39-3.35), 1.31 (0.39-4.42)) or 6 months after total thyroidectomy (1.71 (0.40-7.32), 2.28 (0.53-9.75)). In the nested case-control analysis, rates of treatment for hypocalcemia were similar in patients with and without previous gastric bypass. Previous gastric bypass surgery was infrequent in patients undergoing total thyroidectomy and was not associated with an increased risk of postoperative hypocalcemia.

  8. Surgery of intracranial aneurysms previously treated endovascularly.

    Science.gov (United States)

    Tirakotai, Wuttipong; Sure, Ulrich; Yin, Yuhua; Benes, Ludwig; Schulte, Dirk Michael; Bien, Siegfried; Bertalanffy, Helmut

    2007-11-01

    To perform a retrospective study on the patients who underwent aneurysmal surgery following endovascular treatment. We performed a retrospective study on eight patients who underwent aneurysmal surgery following endovascular treatment (-attempts) with gugliemi detachable coils (GDCs). The indications for surgery, surgical techniques and clinical outcomes were analyzed. The indications for surgical treatment after GDC coiling of aneurysm were classified into three groups. First group: surgery of incompletely coiled aneurysms (n=4). Second group: surgery of mass effect on the neural structures due to coil compaction or rebleeding (n=2). Third group: surgery of vascular complications after endovascular procedure due to parent artery occlusion or thrombus propagation from aneurysm (n=2). Aneurysm obliterations could be performed in all cases confirmed by postoperative angiography. Six patients had an excellent outcome and returned to their profession. Patient's visual acuity was improved. One individual experienced right hemiparesis (grade IV/V) and hemihypesthesia. Microsurgical clipping is rarely necessary for previously coiled aneurysms. Surgical treatment is uncommonly required when an acute complication arises during endovascular treatment, or when there is a dynamic change of a residual aneurysm configuration over time that is considered to be insecure.

  9. The effect of previous traumatic injury on homicide risk.

    Science.gov (United States)

    Griffin, Russell L; Davis, Gregory G; Levitan, Emily B; MacLennan, Paul A; Redden, David T; McGwin, Gerald

    2014-07-01

    Research has reported that a strong risk factor for traumatic injury is having a previous injury (i.e., recidivism). To date, the only study examining the relationship between recidivism and homicide reported strong associations, but was limited by possible selection bias. The current matched case-control study utilized coroner's data from 2004 to 2008. Subjects were linked to trauma registry data to determine whether the person had a previous traumatic injury. Conditional logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (95% CIs) for the association between homicide and recidivism. Homicide risk was increased for those having a previous traumatic injury (OR 1.81, 95% CI 1.09-2.99) or a previous intentional injury (OR 2.53, 95% CI 1.24-5.17). These results suggest an association between homicide and injury recidivism, and that trauma centers may be an effective setting for screening individuals for secondary prevention efforts of homicide through violence prevention programs. © 2014 American Academy of Forensic Sciences.

  10. Antenatal diagnosis of Patau syndrome with previous anomalous baby

    OpenAIRE

    Keerthi Kocherla; Vasantha Kocherla

    2014-01-01

    Patau syndrome is the least common and most severe of the viable autosomal trisomies with median survival of fewer than 3 days was first identified as a cytogenetic syndrome in 1960. Patau syndrome is caused by an extra copy of chromosome 13. In this case report, we present antenatal imaging findings and gross foetal specimen correlation of foetus with Patau syndrome confirmed by karyotyping in third gravida who had significant previous obstetric history of gastrochisis in monochorionic and...

  11. Atrial fibrillation after taser exposure in a previously healthy adolescent.

    Science.gov (United States)

    Multerer, Sara; Berkenbosch, John W; Das, Bibhuti; Johnsrude, Christopher

    2009-12-01

    We are reporting a previously healthy adolescent who developed atrial fibrillation after being tased. He has a structurally normal heart on echocardiogram, normal electrolyte level and thyroid function test results, and a urine toxicology screen positive for marijuana. The patient ultimately required external defibrillation to convert his cardiac rhythm to normal sinus rhythm and has had no recurrent arrhythmias since hospital discharge (approximately 1 year). This is the first reported case of atrial fibrillation developing after a Taser shot, occurring in an adolescent without other risk factors. This case illustrates the arrhythmogenic potential of a Taser in otherwise healthy young individuals, and further study of occurrence of Taser-induced arrhythmias is warranted.

  12. Secondary recurrent miscarriage is associated with previous male birth.

    LENUS (Irish Health Repository)

    Ooi, Poh Veh

    2012-01-31

    Secondary recurrent miscarriage (RM) is defined as three or more consecutive pregnancy losses after delivery of a viable infant. Previous reports suggest that a firstborn male child is associated with less favourable subsequent reproductive potential, possibly due to maternal immunisation against male-specific minor histocompatibility antigens. In a retrospective cohort study of 85 cases of secondary RM we aimed to determine if secondary RM was associated with (i) gender of previous child, maternal age, or duration of miscarriage history, and (ii) increased risk of pregnancy complications. Fifty-three women (62.0%; 53\\/85) gave birth to a male child prior to RM compared to 32 (38.0%; 32\\/85) who gave birth to a female child (p=0.002). The majority (91.7%; 78\\/85) had uncomplicated, term deliveries and normal birth weight neonates, with one quarter of the women previously delivered by Caesarean section. All had routine RM investigations and 19.0% (16\\/85) had an abnormal result. Fifty-seven women conceived again and 33.3% (19\\/57) miscarried, but there was no significant difference in failure rates between those with a previous male or female child (13\\/32 vs. 6\\/25, p=0.2). When patients with abnormal results were excluded, or when women with only one previous child were considered, there was still no difference in these rates. A previous male birth may be associated with an increased risk of secondary RM but numbers preclude concluding whether this increases recurrence risk. The suggested association with previous male birth provides a basis for further investigations at a molecular level.

  13. Secondary recurrent miscarriage is associated with previous male birth.

    LENUS (Irish Health Repository)

    Ooi, Poh Veh

    2011-01-01

    Secondary recurrent miscarriage (RM) is defined as three or more consecutive pregnancy losses after delivery of a viable infant. Previous reports suggest that a firstborn male child is associated with less favourable subsequent reproductive potential, possibly due to maternal immunisation against male-specific minor histocompatibility antigens. In a retrospective cohort study of 85 cases of secondary RM we aimed to determine if secondary RM was associated with (i) gender of previous child, maternal age, or duration of miscarriage history, and (ii) increased risk of pregnancy complications. Fifty-three women (62.0%; 53\\/85) gave birth to a male child prior to RM compared to 32 (38.0%; 32\\/85) who gave birth to a female child (p=0.002). The majority (91.7%; 78\\/85) had uncomplicated, term deliveries and normal birth weight neonates, with one quarter of the women previously delivered by Caesarean section. All had routine RM investigations and 19.0% (16\\/85) had an abnormal result. Fifty-seven women conceived again and 33.3% (19\\/57) miscarried, but there was no significant difference in failure rates between those with a previous male or female child (13\\/32 vs. 6\\/25, p=0.2). When patients with abnormal results were excluded, or when women with only one previous child were considered, there was still no difference in these rates. A previous male birth may be associated with an increased risk of secondary RM but numbers preclude concluding whether this increases recurrence risk. The suggested association with previous male birth provides a basis for further investigations at a molecular level.

  14. Summary Report of Depleted Uranium (DU) Survey Actions at Nevada Test and Training Range (NTTR), Airspace Region 63B, Active Target Complex 10 (63-10)

    Science.gov (United States)

    2016-09-15

    consulting, ionizing radiation protection, exposure, isotope, contamination, health physics, health risk assessment, USAF School of Aerospace... compiled the results of historical reports and data: a. The October 1992 air monitoring results indicated DU contamination remained localized to...suspect of DU munitions contamination be granted to conduct a health risk assessment. d. Based upon 2006 to 2010 scoping surveys of NTTR 63-10

  15. Production of Short-Rotation Woody Crops Grown with a Range of Nutrient and Water Availability: Establishment Report and First-Year Responses

    Science.gov (United States)

    Mark D. Coleman; David R. Coyle; J. Blake; Kerry O. Britton; M. Buford; R.G. Campbell; J. Cox; B. Cregg; D. Daniels; M. Jacobson; Kurt Johnsen; Timothy McDonald; K. McLeod; E. Nelson; D. Robison; R. Rummer; F. Sanchez; John A. Stanturf; B. Stokes; Carl Trettin; J. Tuskan; L. Wright; S. Wullschleger

    2004-01-01

    Many researchers have studied the productivity potential of intensively managed forest plantations. However, we need to learn more about the effects of fundamental growth processes on forest productivity; especially the influence of above- and belowground resource acquisition and allocation. This report presents installation, establishment, and first-year results of...

  16. Installation restoration program, remedial investigation/feasibility study work plan for Indian Mountain long range radar station. Final report, 29 March 1994-15 July 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-07-22

    The remedial investigation (RI)/feasibility study (FS) will investigate sources at both the Upper Camp and Lower Camp, as well as assess the potential for migration of contaminants from the sources. Media to be sampled include surface water, surface soil, subsurface soil, sediment, and groundwater. Field screening techniques will be used, as well as the services of offsite laboratory following completion of the RI, data will be evaluated, an RI/FS report and decision documents will be prepared.

  17. Addendum to the Closure Report for Corrective Action Unit 411: Double Tracks Plutonium Dispersion (Nellis), Nevada Test and Training Range, Nevada, Revision 0

    Energy Technology Data Exchange (ETDEWEB)

    Burmeister, Mark [Navarro, Las Vegas, NV (United States)

    2016-11-01

    The Corrective Action Unit (CAU) 411 Closure Report (CR) was published in June 2016 (NNSA/NFO, 2016). The purpose of this addendum is to clarify language in the CR relating to the field instrument for the detection of low-energy radiation (FIDLER), provide the waste disposal documentation for waste generated during the corrective action investigation (CAI), and reference a letter from the U.S. Air Force (USAF) regarding the closure of CAU 411.

  18. Outcome after arthroscopic labral surgery in patients previously treated with periacetabular osteotomy: a follow-up study of 43 patients

    OpenAIRE

    Hartig-Andreasen, Charlotte; Nielsen, Torsten G.; Lund, Bent; S?balle, Kjeld; Lind, Martin

    2017-01-01

    Abstract To identify factors predicting failure after hip arthroscopy in patients with previous periacetabular osteotomy (PAO) defined as a conversion to total hip replacement (THR) and to evaluate the patient reported outcome scores. Of 55 hips treated with hip arthroscopy after PAO from Aug 2008 to 2012 at Aarhus University Hospital, 43 hips were included (median age: 36.1 yrs, range 16.3?56.9 yrs). Indications were unacceptable pain, a positive FABER and impingement test and signs of labra...

  19. Suicidal imagery in a previously depressed community sample.

    Science.gov (United States)

    Crane, Catherine; Shah, Dhruvi; Barnhofer, Thorsten; Holmes, Emily A

    2012-01-01

    This study sought to replicate previous findings of vivid suicide-related imagery in previously suicidal patients in a community sample of adults with a history of depression. Twenty-seven participants were interviewed regarding suicidal imagery. Seventeen participants reported prior suicidal ideation or behaviour in the clinical assessment, and the vast majority of these also reported experiencing suicide-related imagery when at their most depressed and despairing, in many cases in the form of flash-forwards to imagined future suicidal acts. Interestingly, five of the 10 participants who did not report suicidal ideation or behaviour in the clinical interview also described prominent imagery related to themes of death and suicide, but in several cases, these images were associated with meanings that seemed to act to reduce the likelihood of subsequent suicidal acts. Severity of prior suicidality was associated with lower levels of imagery-related distress and higher levels of imagery-related comfort. These findings support the idea that suicide-related imagery is an important component in the phenomenology of depression and despair and hint at potentially important differences in the meaning associated with such imagery between those individuals who report experiencing suicidal ideation or behaviour when depressed and those who do not. The findings are consistent with Joiner's model of acquired capability for suicide through habituation to pain and fear of suicide and suggest that it may be useful to tackle such imagery directly in the treatment of suicidal patients. Copyright © 2011 John Wiley & Sons, Ltd.

  20. Implants placed in sites of previously failed implants: a systematic review.

    Science.gov (United States)

    Quaranta, Alessandro; Perrotti, Vittoria; Piattelli, Adriano; Piemontese, Matteo; Procaccini, Maurizio

    2014-06-01

    The aim of this study was to systematically review the literature on implant placement in sites of previously failed implants and to assess survival and success rates of the replacement implants to investigate the effectiveness of the procedure. MEDLINE and Cochrane Oral Health Group databases were used to identify articles published between 1985 and 2011. Six articles were selected for a total of 334 patients (338 implants). The survival rate ranged from 71% to 100%. The survival rate for implants placed for the second time (third attempt) in the sites of previously failed implants was 83.75%. No studies included in this review reported the cumulative success rate except for the prospective one, which reported a 93.7% success rate. The main limitations of the present systematic review have been the scarce number of patients and implants in the analyzed studies and the lack of large well-designed case-control long-term trials. Survival rates of implants placed in the areas of previously failed implants are low, although they should not discourage clinicians from a second or even a third attempt.

  1. Baltazor KGRA and vicinity, Nevada: geothermal reservoir assessment case study, northern Basin and Range province. Final report, 1 October 1978-31 January 1983

    Energy Technology Data Exchange (ETDEWEB)

    Wright, T.C.

    1983-01-01

    The Baltazor KGRA and McGee/Painted Hills geothermal prospects are located in northern Humboldt County, Nevada along the northwestern margin of the Basin and Range province. Exploration work other than drilling has included groundwater sampling, a microearthquake study, a geologic literature search and photogeologic mapping, compilation of aeromagnetic and gravity mapping, soil mercury surveying, electrical resistivity and self-potential surveys and detailed hydrothermal alteration mapping. Exploration drilling included 27 shallow temperature gradient holes, four intermediate-depth gradient wells and one 3703-foot deep test, Baltazor 45-14. The deep test penetrated Miocene rhyolite, andesite, basalt and andesitic basalt flows before excessive hold deviation forced an end to drilling and completion as a deep temperature observation well. A temperature survey two weeks after completion obtained a 119.7/sup 0/C (247.4/sup 0/F) reading at survey total depth, 1110 m (3640 feet).

  2. The role of active and ancient geothermal processes in the generation, migration, and entrapment of oil in the basin and Range Province, western USA. Final technical report

    Energy Technology Data Exchange (ETDEWEB)

    Hulen, J.B.; Collister, J.W.; Curtiss, D.K. [and others

    1997-06-01

    The Basin and Range (B&R) physiographic province of the western USA is famous not only for its geothermal and precious-metal wealth, but also for its thirteen oil fields, small but in some cases highly productive. The Grant Canyon field in Railroad Valley, for example, for years boasted production of more than 6000 barrels of oil (BO) per day from just two wells; aggregate current production from the Blackburn field in Pine Valley commonly exceeds 1000 BO per day. These two and several other Nevada oil fields are unusually hot at reservoir depth--up to 130{degrees}C at depths as shallow as 1.1 km, up to three times the value expected from the prevailing regional geothermal gradient.

  3. Rectal prolapse associated with a healed pelvic fracture in a pregnant free-ranging African black rhinoceros (Diceros bicornis. Part 2 : surgery and necropsy : case report

    Directory of Open Access Journals (Sweden)

    A. Olivier

    2001-07-01

    Full Text Available The oedematous and traumatised protruding section of the rectal tissue of an adult free-ranging female African black rhinoceros (Diceros bicornis was surgically amputated. Immediately before completion of surgery, the rhinoceros died of anaesthetic-related cardiac arrest. At necropsy a deformed pelvis and sacrum associated with a healed fracture of the left ileal wing were noted. New bone formation in and around the left ventral sacral foramina may have resulted in neuropathy of particularly the 3rd and 4th left ventral sacral nerves, which (in the horse supply the majority of the nerve fibres innervating the caudal rectum and anus. The cause of the injury is not known, although back injuries, presumably sustained during mating by bulls, have been recorded in white rhinoceros. An encounter with elephants could also have been responsible for the injury in this case.

  4. Rapid Response Initiative Underground Storage Tank Investigations. Site Assessment for Underground Storage Tank Closure Report for Hardwood Range Site, Wisconsin Air National Guard, Volk Field, Camp Douglas, Wisconsin

    Science.gov (United States)

    1994-03-01

    Reactive SW7.3 SW7.3 Density SM271OF SM271OF Flashpoint, Closed Cup SW1010 SW1010 Flashpoint. Open Cup ASTMD4206 ASTMD4206 Fluoride 340.2 Hardness, Total...Cup ASTMD4206 ASTMD4206 Fluoride 340.23Hardness, Total 130.1_ _ Nitrogen, Ammonia 350.2 350.2 Nitrogen, Nitrate 353.2 - Nitrogen, Nitrite 353.2...Measu- Derformed on nitric preserved bottle. 7181-0013 pH (upon receipt) G14 - 1easuI _rforml on nitric Preserved bottle. I I RL = Reporting Limit Ckd : WI

  5. Monitoring of long-range transported air pollutants, Annual report for 2011; Overvaaking av langtransportert forurenset luft og nedboer. Atmosfaeriske tilfoersler, 2011

    Energy Technology Data Exchange (ETDEWEB)

    Aas, Wenche; Solberg, Sverre; Manoe, Stein; Yttri, Karl Espen

    2012-07-01

    This report presents the 2011 monitoring results from the rural air- and precipitation chemistry monitoring network in Norway. In 2011, main components in precipitation were measured at 15 sites. Trace elements were determined at four sites. Air concentrations of sulphur and nitrogen compounds were measured at six sites, and ozone concentrations at eight sites. Persistent organic pollutants and heavy metals in air are determined at three sites. Measurements of PM10 and PM2.5 mass are also determined at three sites, including measurements of organic and elemental carbon (OC and EC). An overview of the measurement programme is given in Appendix B2. (Author)

  6. Rates of induced abortion in Denmark according to age, previous births and previous abortions

    Directory of Open Access Journals (Sweden)

    Marie-Louise H. Hansen

    2009-11-01

    Full Text Available Background: Whereas the effects of various socio-demographic determinants on a woman's risk of having an abortion are relatively well-documented, less attention has been given to the effect of previous abortions and births. Objective: To study the effect of previous abortions and births on Danish women's risk of an abortion, in addition to a number of demographic and personal characteristics. Data and methods: From the Fertility of Women and Couples Dataset we obtained data on the number of live births and induced abortions by year (1981-2001, age (16-39, county of residence and marital status. Logistic regression analysis was used to estimate the influence of the explanatory variables on the probability of having an abortion in a relevant year. Main findings and conclusion: A woman's risk of having an abortion increases with the number of previous births and previous abortions. Some interactions were was found in the way a woman's risk of abortion varies with calendar year, age and parity. The risk of an abortion for women with no children decreases while the risk of an abortion for women with children increases over time. Furthermore, the risk of an abortion decreases with age, but relatively more so for women with children compared to childless women. Trends for teenagers are discussed in a separate section.

  7. High prostate cancer gene 3 (PCA3) scores are associated with elevated Prostate Imaging Reporting and Data System (PI-RADS) grade and biopsy Gleason score, at magnetic resonance imaging/ultrasonography fusion software-based targeted prostate biopsy after a previous negative standard biopsy.

    Science.gov (United States)

    De Luca, Stefano; Passera, Roberto; Cattaneo, Giovanni; Manfredi, Matteo; Mele, Fabrizio; Fiori, Cristian; Bollito, Enrico; Cirillo, Stefano; Porpiglia, Francesco

    2016-11-01

    To determine the association among prostate cancer gene 3 (PCA3) score, Prostate Imaging Reporting and Data System (PI-RADS) grade and Gleason score, in a cohort of patients with elevated prostate-specific antigen (PSA), undergoing magnetic resonance imaging/ultrasonography fusion software-based targeted prostate biopsy (TBx) after a previous negative randomised 'standard' biopsy (SBx). In all, 282 patients who underwent TBx after previous negative SBx and a PCA3 urine assay, were enrolled. The associations between PCA3 score/PI-RADS and PCA3 score/Gleason score were investigated by K-means clustering, a receiver operating characteristic analysis and binary logistic regression. The PCA3 score difference for the negative vs positive TBx cohorts was highly statistically significant. A 1-unit increase in the PCA3 score was associated to a 2.4% increased risk of having a positive TBx result. A PCA3 score of >80 and a PI-RADS grade of ≥4 were independent predictors of a positive TBx. The association between the PCA3 score and PI-RADS grade was statistically significant (the median PCA3 score for PI-RADS grade groups 3, 4, and 5 was 58, 104, and 146, respectively; P = 0.006). A similar pattern was detected for the relationship between the PCA3 score and Gleason score; an increasing PCA3 score was associated with a worsening Gleason score (median PCA3 score equal to 62, 105, 132, 153, 203, and 322 for Gleason Score 3+4, 4+3, 4+4, 4+5, 5+4, and 5+5, respectively; P PI-RADS grade: notably, in the 'indeterminate' PI-RADS grade 3 subgroup. © 2016 The Authors BJU International © 2016 BJU International Published by John Wiley & Sons Ltd.

  8. Evaluation of geothermal potential of Rio Grande rift and Basin and Range province, New Mexico. Final technical report, January 1, 1977-May 31, 1978

    Energy Technology Data Exchange (ETDEWEB)

    Callender, J.F.

    1985-04-01

    A study was made of the geological, geochemical and geophysical characteristics of potential geothermal areas in the Rio Grande rift and Basin and Range province of New Mexico. Both regional and site-specific information is presented. Data was collected by: (1) reconnaissance and detailed geologic mapping, emphasizing Neogene stratigraphy and structure; (2) petrologic studies of Neogene igneous rocks; (3) radiometric age-dating; (4) geochemical surveying, including regional and site-specific water chemistry, stable isotopic analyses of thermal waters, whole-rock and mineral isotopic studies, and whole-rock chemical analyses; and (5) detailed geophysical surveys, using electrical, gravity and magnetic techniques, with electrical resistivity playing a major role. Regional geochemical water studies were conducted for the whole state. Integrated site-specific studies included the Animas Valley, Las Cruces area (Radium Springs and Las Alturas Estates), Truth or Consequences region, the Albuquerque basin, the San Ysidro area, and the Abiquiu-Ojo Caliente region. The Animas Valley and Las Cruces areas have the most significant geothermal potential of the areas studied. The Truth or Consequences and Albuquerque areas need further study. The San Ysidro and Abiquiu-Ojo Caliente regions have less significant geothermal potential. 78 figs., 16 tabs.

  9. Preliminary report of an ongoing phase I/II dose range, safety and efficacy study of iodine-123-phenylpentadecanoic acid for the identification of viable myocardium.

    Science.gov (United States)

    Hansen, C L

    1994-04-01

    An agent that can accurately and cost-effectively identify viable myocardium is needed to select the patients most likely to benefit from myocardial revascularization. Iodine-123-phenylpentadecanoic acid (IPPA) is a synthetic radiolabeled fatty acid that has shown promise in evaluating patients with coronary artery disease (CAD). IPPA has unique metabolic properties that may make it superior to other single-photon agents used for this task. A Phase I/II study is underway to evaluate safety, dose range and efficacy of IPPA in assessing viability and predicting functional recovery after revascularization. Patients between the ages of 21 and 75 with angiographically documented CAD, who were being referred for coronary revascularization, were recruited. The patients were randomized to receive 2, 4 or 6 mCi of IPPA and then underwent sequential SPECT imaging at 4, 12, 20, 28 and 36 min after injection. Radionuclide ventriculography and perfusion imaging were performed before and again 8 wk after revascularization. Myocardial metabolic activity of IPPA was analyzed and compared to the preinjection and postejection fractions. There were no significant adverse effects from the administration of IPPA. Image quality was dose-dependent; the 2-mCi dose was not consistently acceptable for quantitative analysis. These preliminary data show that IPPA is safe and can produce myocardial images of good quality when 4 mCi or more are used. Early results are encouraging but more experience will be needed to define the role of IPPA in identifying myocardial viability.

  10. Design and development of Stirling engines for stationary-power-generation applications in the 500- to 3000-hp range. Phase I final report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-10-01

    The first phase of the design and development of Stirling engines for stationary power generation applications in the 373 kW (500 hp) to 2237 kW (3000 hp) range was completed. The tasks in Phase I include conceptual designs of large Stirling cycle stationary engines and program plan for implementing Phases II through V. Four different heater head designs and five different machine designs were prepared in sufficient detail to select a design recommended for development in the near future. A second order analysis was developed for examining the various loss mechanisms in the Stirling engine and for predicting the thermodynamic performance of these engines. The predicted engine thermal brake efficiency excluding combustion efficiency is approximately 42% which exceeds the design objective of 40%. The combustion system designs were prepared for both a clean fuel combustion system and a two-stage atmospheric fluidized bed combustion system. The calculated combustion efficiency of the former is 90% and of the latter is 80%. Heat transport systems, i.e., a heat exchanger for the clean fuel combustion system and a sodium heat pipe system for coal and other nonclean fuel combustion systems were selected. The cost analysis showed that for clean fuels combustion the proposed 2237 kW (3000 hp) system production cost is $478,242 or $214/kW ($159/hp) which is approximately 1.86 times the cost of a comparable size diesel engine. For solid coal combustion the proposed 2237 kW (3000 hp) system production cost is approximately $2,246,242 which corresponds to a cost to power capacity ratio of $1004/kW ($749/hp). The two-stage atmospheric fluidized bed combustion system represents 81% of the total cost; the engine represents 14% depending on the future price differential between coal and conventional clean fuels, a short payback period of the proposed Stirling cycle engine/FBC system may justify the initial cost. (LCL)

  11. Design and development of Stirling engines for stationary power generation applications in the 500 to 3000 horsepower range. First quarterly report

    Energy Technology Data Exchange (ETDEWEB)

    ,

    1980-01-07

    This project is Phase I of a multi-phased program for the design and development of Stirling engines for stationary power generation applications in the 500 to 3000 horsepower range. Phase I comprises the conceptual design and associated cost estimates of a stationary Stirling engine capable of being fueled by a variety of heat sources, with emphasis on coal firing, followed by the preparation of a plan for implementing the design, fabrication and testing of a demonstration engine by 1985. The main effort in Phase I is the generation of state-of-the-art conceptual designs having greatest potential for prototype testing in 1985. The conceptual designs include a heat transport system for integrating the engine heater head with such energy sources as conventional oil/gas combustors, fluidized bed and other coal combustors, and combustors using coal-derived liquid fuels, and low/medium BTU gases. The heat transport systems being investigated include forced convection with gases or liquids, heat pipes, and direct firing. Currently, the leading choice for the solid fuel combustion system is the atmospheric fluidized bed, with low BTU gasification still a viable alternative. Both systems will continue to be evaluated further, but with greater emphasis on FBC. To date, there appears no clear choice among the heat pipe, forced convection gas loop, or direct firing as the prime candidate for the heat transport sub-system. Conceptual design and analysis will continue on all three sub-systems. Scale-up of United Stirling's P-75 engine to serve as the conceptual design of the 500 HP engine module is continuing. (LCL)

  12. Range data reported to the requirements of the IAS 12 and impact of the IFRS adoption for tax purposes in the tax collection of the Czech Republic

    Directory of Open Access Journals (Sweden)

    Simona Jirásková

    2013-01-01

    Full Text Available An issue of relationship between corporate income tax and accounting is one of the most discussed at present. Until recently the tax base was derived from the accounting profit defined in the Czech accounting law. But from 2004 there are companies which have to use IFRS in bookkeeping and financial reporting and from the perspective of the Czech accounting law they do not care about Czech accounting regulation. On the other hand Czech tax regulation has not accepted this change in the field of European accounting harmonization and still directs to pay tax on the basis of Czech accounting regulation for all entities. Fear of adverse change in tax collection is one of the main reasons why the Czech Tax Administration does not allow to pay income tax under profit or loss patterned on IFRS. The most important goal of this work is to characterize the relationship between accounting profit or loss under IFRS and the tax base of income and to find out the impact of taxation under profit in accordance with IFRS in total tax collection. Basic sample of all analyses consists of 35 accounting entities which mandatorily use IFRS and this sample was also confronted with a list of 106 major payers of income tax published yearly by the Ministry of Finance of the Czech Republic for the needs characterization of the relationship of profit under IFRS and the tax base of income.

  13. Cutaneous protothecosis in a patient with previously undiagnosed HIV infection.

    Science.gov (United States)

    Fong, Kenneth; Tee, Shang-Ian; Ho, Madeline S L; Pan, Jiun Yit

    2015-08-01

    Protothecosis is an uncommon condition resulting from infection by achlorophyllous algae of the Prototheca species. Immunocompromised individuals are generally most susceptible to protothecal infection and tend to develop severe and disseminated disease. However, the association between protothecosis and HIV-induced immunosuppression is not clear, with only a handful of cases having been described to date. Here we report a case of cutaneous protothecosis in a Chinese man with previously undiagnosed HIV infection that responded well to oral itraconazole. © 2014 The Australasian College of Dermatologists.

  14. Risk for surgical complications after previous stereotactic body radiotherapy of the spine.

    Science.gov (United States)

    Roesch, Johannes; Cho, John B C; Fahim, Daniel K; Gerszten, Peter C; Flickinger, John C; Grills, Inga S; Jawad, Maha; Kersh, Ronald; Letourneau, Daniel; Mantel, Frederick; Sahgal, Arjun; Shin, John H; Winey, Brian; Guckenberger, Matthias

    2017-09-11

    Stereotactic body radiotherapy (SBRT) for vertebral metastases has emerged as a promising technique, offering high rates of symptom relief and local control combined with low risk of toxicity. Nonetheless, local failure or vertebral instability may occur after spine SBRT, generating the need for subsequent surgery in the irradiated region. This study evaluated whether there is an increased incidence of surgical complications in patients previously treated with SBRT at the index level. Based upon a retrospective international database of 704 cases treated with SBRT for vertebral metastases, 30 patients treated at 6 different institutions were identified who underwent surgery in a region previously treated with SBRT. Thirty patients, median age 59 years (range 27-84 years) underwent SBRT for 32 vertebral metastases followed by surgery at the same vertebra. Median follow-up time from SBRT was 17 months. In 17 cases, conventional radiotherapy had been delivered prior to SBRT at a median dose of 30 Gy in median 10 fractions. SBRT was administered with a median prescription dose of 19.3 Gy (range 15-65 Gy) delivered in median 1 fraction (range 1-17) (median EQD2/10 = 44 Gy). The median time interval between SBRT and surgical salvage therapy was 6 months (range 1-39 months). Reasons for subsequent surgery were pain (n = 28), neurological deterioration (n = 15) or fracture of the vertebral body (n = 13). Open surgical decompression (n = 24) and/or stabilization (n = 18) were most frequently performed; Five patients (6 vertebrae) were treated without complications with vertebroplasty only. Increased fibrosis complicating the surgical procedure was explicitly stated in one surgical report. Two durotomies occurred which were closed during the operation, associated with a neurological deficit in one patient. Median blood loss was 500 ml, but five patients had a blood loss of more than 1 l during the procedure. Delayed wound healing was reported in two

  15. Report to Congress on Sustainable Ranges, 2009

    Science.gov (United States)

    2009-05-01

    Islands National Marine Sanctuary, designation of new state marine protected areas around San Nicolas Island, proposed liquefied natural gas...restrictions on new activities in the Channel Islands National Marine Sanctuary, designation of new state marine protected areas around San Nicolas Island...Species/Critical Habitat Strategic Attack A proposal to establish Marine Protected Areas (MPAs) or Monuments in the northern Gulf of Mexico has the

  16. Report to Congress on Sustainable Ranges, 2012

    Science.gov (United States)

    2012-05-01

    Plans ( QAPs ) in August 2008 to improve consistency and coordination of all installation geospatial data. All Army installations are required to...Center) are defined in each layer’s geospatial data QAP . QAPs provide the definition, information about the functional and organizational proponent...layers. QAPs are living documents and are maintained by the HQDA proponent with input from the installation data stewards and other stakeholders

  17. High-Grade Leiomyosarcoma Arising in a Previously Replanted Limb

    Directory of Open Access Journals (Sweden)

    Tiffany J. Pan

    2015-01-01

    Full Text Available Sarcoma development has been associated with genetics, irradiation, viral infections, and immunodeficiency. Reports of sarcomas arising in the setting of prior trauma, as in burn scars or fracture sites, are rare. We report a case of a leiomyosarcoma arising in an arm that had previously been replanted at the level of the elbow joint following traumatic amputation when the patient was eight years old. He presented twenty-four years later with a 10.8 cm mass in the replanted arm located on the volar forearm. The tumor was completely resected and pathology examination showed a high-grade, subfascial spindle cell sarcoma diagnosed as a grade 3 leiomyosarcoma with stage pT2bNxMx. The patient underwent treatment with brachytherapy, reconstruction with a free flap, and subsequently chemotherapy. To the best of our knowledge, this is the first case report of leiomyosarcoma developing in a replanted extremity. Development of leiomyosarcoma in this case could be related to revascularization, scar formation, or chronic injury after replantation. The patient remains healthy without signs of recurrence at three-year follow-up.

  18. Range management visual impacts

    Science.gov (United States)

    Bruce R. Brown; David Kissel

    1979-01-01

    Historical overgrazing of western public rangelands has resulted in the passage of the Public Rangeland Improvement Act of 1978. The main purpose of this Act is to improve unsatisfactory range conditions. A contributing factor to unfavorable range conditions is adverse visual impacts. These visual impacts can be identified in three categories of range management: range...

  19. HEART TRANSPLANTATION IN PATIENTS WITH PREVIOUS OPEN HEART SURGERY

    Directory of Open Access Journals (Sweden)

    R. Sh. Saitgareev

    2016-01-01

    cited in the review may have important clinical applications, because they outline the range of problems and possible solutions in the performance of the HTx in recipients previously operated on open heart. This knowledge can facilitate the decision making process with regard to the opportunities and risks of the implementation of HTx. Given the uniqueness of each of the recipient and the donor, it is required to make a personalized approach to the question of the possible risks and to the preventive measures to reduce those risks in any given clinical situation. 

  20. Malignant tumor formation in dogs previously irradiated for acanthomatous epulis.

    Science.gov (United States)

    McEntee, Margaret C; Page, Rodney L; Théon, Alain; Erb, Hollis N; Thrall, Donald E

    2004-01-01

    In this retrospective study of 57 dogs irradiated for oral acanthomatous epulis, 2 (3.5%) dogs developed a second tumor (sarcoma, osteosarcoma) in the radiation treatment field at 5.2 and 8.7 years after the end of radiation therapy. As opposed to previous reports, no second epithelial tumors developed in the radiation treatment field. There is a risk of radiation-induced carcinogenesis, but it appears that it is a relatively low risk and an event that occurs years after radiation therapy. Radiation-induced tumors are of more concern in younger dogs that undergo radiation therapy for tumors that are radioresponsive, such as acanthomatous epulis, where long-term survival is expected. The only statistically significant variable in the survival analysis was age, with dogs less than 8.3 years old having a significantly longer median overall survival (2322 days) than dogs older than 8.3 years (1106 days; P<0.0001).

  1. Ranging Behaviour of Commercial Free-Range Laying Hens

    Directory of Open Access Journals (Sweden)

    Leonard Ikenna Chielo

    2016-04-01

    Full Text Available In this study, the range use and behaviour of laying hens in commercial free-range flocks was explored. Six flocks were each visited on four separate days and data collected from their outdoor area (divided into zones based on distance from shed and available resources. These were: apron (0–10 m from shed normally without cover or other enrichments; enriched belt (10–50 m from shed where resources such as manmade cover, saplings and dust baths were provided; and outer range (beyond 50 m from shed with no cover and mainly grass pasture. Data collection consisted of counting the number of hens in each zone and recording behaviour, feather condition and nearest neighbour distance (NND of 20 birds per zone on each visit day. In addition, we used techniques derived from ecological surveys to establish four transects perpendicular to the shed, running through the apron, enriched belt and outer range. Number of hens in each 10 m × 10 m quadrat was recorded four times per day as was the temperature and relative humidity of the outer range. On average, 12.5% of hens were found outside. Of these, 5.4% were found in the apron; 4.3% in the enriched zone; and 2.8% were in the outer range. This pattern was supported by data from quadrats, where the density of hens sharply dropped with increasing distance from shed. Consequently, NND was greatest in the outer range, least in the apron and intermediate in the enriched belt. Hens sampled in outer range and enriched belts had better feather condition than those from the apron. Standing, ground pecking, walking and foraging were the most commonly recorded activities with standing and pecking most likely to occur in the apron, and walking and foraging more common in the outer range. Use of the outer range declined with lower temperatures and increasing relative humidity, though use of apron and enriched belt was not affected by variation in these measures. These data support previous findings that outer range

  2. Ranging Behaviour of Commercial Free-Range Laying Hens.

    Science.gov (United States)

    Chielo, Leonard Ikenna; Pike, Tom; Cooper, Jonathan

    2016-04-26

    In this study, the range use and behaviour of laying hens in commercial free-range flocks was explored. Six flocks were each visited on four separate days and data collected from their outdoor area (divided into zones based on distance from shed and available resources). These were: apron (0-10 m from shed normally without cover or other enrichments); enriched belt (10-50 m from shed where resources such as manmade cover, saplings and dust baths were provided); and outer range (beyond 50 m from shed with no cover and mainly grass pasture). Data collection consisted of counting the number of hens in each zone and recording behaviour, feather condition and nearest neighbour distance (NND) of 20 birds per zone on each visit day. In addition, we used techniques derived from ecological surveys to establish four transects perpendicular to the shed, running through the apron, enriched belt and outer range. Number of hens in each 10 m × 10 m quadrat was recorded four times per day as was the temperature and relative humidity of the outer range. On average, 12.5% of hens were found outside. Of these, 5.4% were found in the apron; 4.3% in the enriched zone; and 2.8% were in the outer range. This pattern was supported by data from quadrats, where the density of hens sharply dropped with increasing distance from shed. Consequently, NND was greatest in the outer range, least in the apron and intermediate in the enriched belt. Hens sampled in outer range and enriched belts had better feather condition than those from the apron. Standing, ground pecking, walking and foraging were the most commonly recorded activities with standing and pecking most likely to occur in the apron, and walking and foraging more common in the outer range. Use of the outer range declined with lower temperatures and increasing relative humidity, though use of apron and enriched belt was not affected by variation in these measures. These data support previous findings that outer range areas tend to be

  3. Report on AFRIMETS supplementary comparison: platinum resistance thermometer and digital thermometer calibrations against ITS-90 over the range -50 °C to 450 °C (AFRIMETS.T-S1)

    Science.gov (United States)

    Liedberg, Hans; Abdelaziz, Yasser; Tesfaye, Fitsum; Egadwa, Wilson; Norranim, Uthai; Rwashana, Simon; Kagoma, Alphonce; Ziagi, Adam; Kwong, Christian Ng Ha; Madeleine, Gilbert

    2017-01-01

    A Regional Metrology Organization (RMO) supplementary comparison of platinum resistance thermometer and digital thermometer (AFRIMETS.T-S1) was carried out by the National Metrology Institute of South Africa (NMISA), National Institute for Standards Egypt (NIS), National Metrology Institute of Ethiopia (NMIE), Kenya Bureau of Standards (KEBS), National Institute of Metrology Thailand (NIMT), Uganda National Bureau of Standards (UNBS), Tanzania Bureau of Standards (TBS), Mauritius Standards Bureau (MSB) and Seychelles Bureau of Standards (SBS) between March 2008 and October 2010. The temperature range of the inter comparison is -50 °C to 450 °C. The results of this comparison are reported here, along with descriptions of the Artefacts and devices used during measurement. This report also presents the uncertainty budget. The results are analysed and normalized error (En) values are reported. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCT, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

  4. Colored Range Searching in Linear Space

    DEFF Research Database (Denmark)

    Grossi, Roberto; Vind, Søren Juhl

    2014-01-01

    In colored range searching, we are given a set of n colored points in d ≥ 2 dimensions to store, and want to support orthogonal range queries taking colors into account. In the colored range counting problem, a query must report the number of distinct colors found in the query range, while...... an answer to the colored range reporting problem must report the distinct colors in the query range. We give the first linear space data structure for both problems in two dimensions (d = 2) with o(n) worst case query time. We also give the first data structure obtaining almost-linear space usage and o...

  5. Twelve previously unknown phage genera are ubiquitous in global oceans.

    Science.gov (United States)

    Holmfeldt, Karin; Solonenko, Natalie; Shah, Manesh; Corrier, Kristen; Riemann, Lasse; Verberkmoes, Nathan C; Sullivan, Matthew B

    2013-07-30

    Viruses are fundamental to ecosystems ranging from oceans to humans, yet our ability to study them is bottlenecked by the lack of ecologically relevant isolates, resulting in "unknowns" dominating culture-independent surveys. Here we present genomes from 31 phages infecting multiple strains of the aquatic bacterium Cellulophaga baltica (Bacteroidetes) to provide data for an underrepresented and environmentally abundant bacterial lineage. Comparative genomics delineated 12 phage groups that (i) each represent a new genus, and (ii) represent one novel and four well-known viral families. This diversity contrasts the few well-studied marine phage systems, but parallels the diversity of phages infecting human-associated bacteria. Although all 12 Cellulophaga phages represent new genera, the podoviruses and icosahedral, nontailed ssDNA phages were exceptional, with genomes up to twice as large as those previously observed for each phage type. Structural novelty was also substantial, requiring experimental phage proteomics to identify 83% of the structural proteins. The presence of uncommon nucleotide metabolism genes in four genera likely underscores the importance of scavenging nutrient-rich molecules as previously seen for phages in marine environments. Metagenomic recruitment analyses suggest that these particular Cellulophaga phages are rare and may represent a first glimpse into the phage side of the rare biosphere. However, these analyses also revealed that these phage genera are widespread, occurring in 94% of 137 investigated metagenomes. Together, this diverse and novel collection of phages identifies a small but ubiquitous fraction of unknown marine viral diversity and provides numerous environmentally relevant phage-host systems for experimental hypothesis testing.

  6. Minnesota Pheasant Range

    Data.gov (United States)

    Minnesota Department of Natural Resources — This dataset delineates the spatial range of wild pheasant populations in Minnesota as of 2002 by dividing the MN state boundary into 2 units: pheasant range and...

  7. Measles Outbreak among Previously Immunized Adult Healthcare Workers, China, 2015

    Directory of Open Access Journals (Sweden)

    Zhengyi Zhang

    2016-01-01

    Full Text Available Measles is caused by measles virus belonging to genus Morbillivirus of the family Paramyxoviridae. Vaccination has played a critical role in controlling measles infection worldwide. However, in the recent years, outbreaks of measles infection still occur in many developing countries. Here, we report an outbreak of measles among healthcare workers and among the 60 measles infected patients 50 were healthcare workers including doctors, nurses, staff, and medics. Fifty-one patients (85% tested positive for IgM antibodies against the measles virus and 50 patients (83.3% tested positive for measles virus RNA. Surprisingly, 73.3% of the infected individuals had been previously immunized against measles. Since there is no infection division in our hospital, the fever clinics are located in the Emergency Division. In addition, the fever and rash were not recognized as measles symptoms at the beginning of the outbreak. These factors result in delay in isolation and early confirmation of the suspected patients and eventually a measles outbreak in the hospital. Our report highlights the importance of following a two-dose measles vaccine program in people including the healthcare workers. In addition, vigilant attention should be paid to medical staff with clinical fever and rash symptoms to avoid a possible nosocomial transmission of measles infection.

  8. Cerebral Metastasis from a Previously Undiagnosed Appendiceal Adenocarcinoma

    Directory of Open Access Journals (Sweden)

    Antonio Biroli

    2012-01-01

    Full Text Available Brain metastases arise in 10%–40% of all cancer patients. Up to one third of the patients do not have previous cancer history. We report a case of a 67-years-old male patient who presented with confusion, tremor, and apraxia. A brain MRI revealed an isolated right temporal lobe lesion. A thorax-abdomen-pelvis CT scan showed no primary lesion. The patient underwent a craniotomy with gross-total resection. Histopathology revealed an intestinal-type adenocarcinoma. A colonoscopy found no primary lesion, but a PET-CT scan showed elevated FDG uptake in the appendiceal nodule. A right hemicolectomy was performed, and the specimen showed a moderately differentiated mucinous appendiceal adenocarcinoma. Whole brain radiotherapy was administrated. A subsequent thorax-abdomen CT scan revealed multiple lung and hepatic metastasis. Seven months later, the patient died of disease progression. In cases of undiagnosed primary lesions, patients present in better general condition, but overall survival does not change. Eventual identification of the primary tumor does not affect survival. PET/CT might be a helpful tool in detecting lesions of the appendiceal region. To the best of our knowledge, such a case was never reported in the literature, and an appendiceal malignancy should be suspected in patients with brain metastasis from an undiagnosed primary tumor.

  9. Gastrointestinal tolerability with ibandronate after previous weekly bisphosphonate treatment

    Directory of Open Access Journals (Sweden)

    Richard Derman

    2009-09-01

    Full Text Available Richard Derman1, Joseph D Kohles2, Ann Babbitt31Department of Obstetrics and Gynecology, Christiana Hospital, Newark, DE, USA; 2Roche, Nutley, NJ, USA; 3Greater Portland Bone and Joint Specialists, Portland, ME, USAAbstract: Data from two open-label trials (PRIOR and CURRENT of women with postmenopausal osteoporosis or osteopenia were evaluated to assess whether monthly oral and quarterly intravenous (IV ibandronate dosing improved self-reported gastrointestinal (GI tolerability for patients who had previously experienced GI irritation with bisphosphonate (BP use. In PRIOR, women who had discontinued daily or weekly BP treatment due to GI intolerance received monthly oral or quarterly IV ibandronate for 12 months. The CURRENT subanalysis included women receiving weekly BP treatment who switched to monthly oral ibandronate for six months. GI symptom severity and frequency were assessed using the Osteoporosis Patient Satisfaction Questionnaire™. In PRIOR, mean GI tolerability scores increased significantly at month 1 from screening for both treatment groups (oral: 79.3 versus 54.1; IV: 84.4 versus 51.0; p < 0.001 for both. Most patients reported improvement in GI symptom severity and frequency from baseline at all post-screening assessments (>90% at Month 10. In the CURRENT subanalysis >60% of patients reported improvements in heartburn or acid reflux and >70% indicated improvement in other stomach upset at month 6. Postmenopausal women with GI irritability with daily or weekly BPs experienced improvement in symptoms with extended dosing monthly or quarterly ibandronate compared with baseline.Keywords: ibandronate, osteoporosis, bisphosphonate, gastrointestinal

  10. Final report of key comparison AFRIMETS.AUV.A-K5: primary pressure calibration of LS1P microphones according to IEC 61094-2, over the frequency range 2 Hz to 10 kHz.

    Science.gov (United States)

    Nel, R.; Avison, J.; Harris, P.; Blabla, M.; Hämäläinen, J.

    2017-01-01

    The degrees of equivalence of the AFRIMETS.AUV.A-K5 regional key comparison are reported here as the final report. The scope of the comparison covered the complex pressure sensitivities of two LS1P microphones over the frequency range 2 Hz to 10 kHz in accordance with IEC 61094-2: 2009. Four national metrology institutes from two different regional metrology organisations participated in the comparison. Two LS1P microphones were circulated simultaneously to all the participants in a circular configuration. One of the microphones sensitivity shifted and all results associated with this microphone were subsequently excluded from further analysis and linking. The AFRIMETS.AUV.A-K5 comparison results were linked to the CCAUV.A-K5 comparison results via dual participation in the CCAUV.A-K5 and AFRIMETS.AUV.A-K5 comparisons. The degrees of equivalence, linked to the CCAUV.A-K5 comparison, were calculated for all participants of this comparison. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCAUV, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

  11. Optimal temperature for malaria transmission is dramaticallylower than previously predicted

    Science.gov (United States)

    Mordecai, Eerin A.; Paaijmans, Krijin P.; Johnson, Leah R.; Balzer, Christian; Ben-Horin, Tal; de Moor, Emily; McNally, Amy; Pawar, Samraat; Ryan, Sadie J.; Smith, Thomas C.; Lafferty, Kevin D.

    2013-01-01

    The ecology of mosquito vectors and malaria parasites affect the incidence, seasonal transmission and geographical range of malaria. Most malaria models to date assume constant or linear responses of mosquito and parasite life-history traits to temperature, predicting optimal transmission at 31 °C. These models are at odds with field observations of transmission dating back nearly a century. We build a model with more realistic ecological assumptions about the thermal physiology of insects. Our model, which includes empirically derived nonlinear thermal responses, predicts optimal malaria transmission at 25 °C (6 °C lower than previous models). Moreover, the model predicts that transmission decreases dramatically at temperatures > 28 °C, altering predictions about how climate change will affect malaria. A large data set on malaria transmission risk in Africa validates both the 25 °C optimum and the decline above 28 °C. Using these more accurate nonlinear thermal-response models will aid in understanding the effects of current and future temperature regimes on disease transmission.

  12. Improved Range Searching Lower Bounds

    DEFF Research Database (Denmark)

    Larsen, Kasper Green; Nguyen, Huy L.

    2012-01-01

    by constructing a hard input set and query set, and then invoking Chazelle and Rosenberg's [CGTA'96] general theorem on the complexity of navigation in the pointer machine. For the group model, we show that input sets and query sets that are hard for range reporting in the pointer machine (i.e. by Chazelle...

  13. Endoscopic sinus surgery for chronic rhinosinusitis in patients previously treated for sinonasal malignancy.

    Science.gov (United States)

    Gray, Stacey T; Sadow, Peter M; Lin, Derrick T; Sedaghat, Ahmad R

    2016-02-01

    Patients with a history of sinonasal malignancy can develop chronic rhinosinusitis (CRS) as a consequence of their oncologic treatment. Some patients will fail medical management and require endoscopic sinus surgery (ESS). This study reviews the use of ESS in the management of CRS in patients previously treated for sinonasal malignancy. Retrospective review. All patients with a history of sinonasal malignancy who developed CRS and underwent ESS were reviewed. Preoperative and postoperative imaging and symptoms were collected. Major complications (bleeding, orbital injury, and cerebrospinal fluid leak) and minor complications (adhesion formation) and postoperative healing were reviewed. Eighteen patients were identified. All patients presented with symptoms of CRS and sinonasal crusting. Additionally, five patients presented with recurrent facial cellulitis, and six patients had mucoceles. No major complications were encountered. Postoperatively, all patients reported a subjective improvement in their sinonasal symptoms. Comparison of pre- and post-ESS imaging revealed a significant improvement in Lund-Mackay scores after ESS (P < 0.001) from 12.8 (range 5-22) to 7 (range). Despite symptomatic improvement, all patients continued to have nasal crusting. All patients who initially presented with recurrent facial cellulitis had no further episodes after ESS. None of the endoscopically drained mucoceles recurred. For patients previously treated for sinonasal malignancy with refractory CRS, ESS appears to be a safe and effective treatment option. ESS in these patients results in subjective improvement in sinonasal symptoms as well as objective improvement in radiographic CRS disease burden, although sinonasal crusting will likely not resolve. 4. © 2015 The American Laryngological, Rhinological and Otological Society, Inc.

  14. Is the Universe More Transparent to Gamma Rays than Previously Thought?

    Science.gov (United States)

    Stecker, Floyd W.; Scully, Sean T.

    2009-01-01

    The MAGIC collaboration has recently reported the detection of the strong gamma-ray blazar 3C279 during a 1-2 day flare. They have used their spectral observations to draw conclusions regarding upper limits on the opacity of the Universe to high energy gamma-rays and, by implication, upper limits on the extragalactic mid-infrared background radiation. In this paper we examine the effect of gamma-ray absorption by the extragalactic infrared radiation on intrinsic spectra for this blazar and compare our results with the observational data on 3C279. We find agreement with our previous results, contrary to the recent assertion of the MAGIC group that the Universe is more transparent to gamma-rays than our calculations indicate. Our analysis indicates that in the energy range between approx. 80 and approx. 500 GeV, 3C279 has a best-fit intrinsic spectrum with a spectral index approx. 1.78 using our fast evolution model and approx. 2.19 using our baseline model. However, we also find that spectral indices in the range of 1.0 to 3.0 are almost as equally acceptable as the best fit spectral indices. Assuming the same intrinsic spectral index for this flare as for the 1991 flare from 3C279 observed by EGRET, viz., 2.02, which lies between our best fit indeces, we estimate that the MAGIC flare was approx.3 times brighter than the EGRET flare observed 15 years earlier.

  15. 22 CFR 40.91 - Certain aliens previously removed.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Certain aliens previously removed. 40.91... IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Aliens Previously Removed § 40.91 Certain aliens previously removed. (a) 5-year bar. An alien who has been found inadmissible, whether as a result...

  16. Compact Antenna Range

    Data.gov (United States)

    Federal Laboratory Consortium — Facility consists of a folded compact antenna range including a computer controlled three axis position table, parabolic reflector and RF sources for the measurement...

  17. Dryden Aeronautical Test Range

    Data.gov (United States)

    Federal Laboratory Consortium — Recently redesignated to honor Dr. Hugh L. Dryden, NASA's Dryden Aeronautical Test Range (DATR) supports aerospace flight research and technology integration, space...

  18. Pleomorphic dermal sarcoma: a more aggressive neoplasm than previously estimated.

    Science.gov (United States)

    Tardío, Juan C; Pinedo, Fernando; Aramburu, José A; Suárez-Massa, Dolores; Pampín, Ana; Requena, Luis; Santonja, Carlos

    2016-02-01

    Pleomorphic dermal sarcoma (PDS) is a rare neoplasm sharing pathological features with atypical fibroxanthoma, but adding tumor necrosis, invasion beyond superficial subcutis or vascular or perineural infiltration. Although its metastatic risk has been estimated to be less than 5%, its real outcome is presently uncertain because of its rarity and to the lack of homogeneous criteria used in reported cases. Retrospective clinicopathological study of 18 cases of PDS. The lesions presented as tumors or plaques (size: 7-70 mm) on the head of elderly patients (median: 81 years), without a gender predominance. Histopathologically, they consisted of spindle cells arranged in a fascicular pattern, containing pleomorphic epithelioid and giant multinucleated cells in varying proportions, and usually exhibiting numerous mitotic figures and infiltrative tumor margins. No immunoexpression for cytokeratins, S100 protein, desmin or CD34 was observed. Necrosis and venous invasion were found in three tumors each (17%). Follow-up was available in 15 cases (median: 33 months). Three patients (20%) had local recurrences, all with incomplete primary surgical resections. Three patients (20%) developed distant metastases in the skin, regional lymph nodes and/or lungs and died from the disease. Our data suggest that PDS may be a more aggressive neoplasm than previously estimated. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  19. On Range of Skill

    DEFF Research Database (Denmark)

    Hansen, Thomas Dueholm; Miltersen, Peter Bro; Sørensen, Troels Bjerre

    2008-01-01

    size (and doubly exponential in its depth). We also provide techniques that yield concrete bounds for unbalanced game trees and apply these to estimate the Range of Skill of Tic-Tac-Toe and Heads-Up Limit Texas Hold'em Poker. In particular, we show that the Range of Skill of Tic-Tac-Toe is more than...

  20. Range Scheduling Aid (RSA)

    Science.gov (United States)

    Logan, J. R.; Pulvermacher, M. K.

    1991-01-01

    Range Scheduling Aid (RSA) is presented in the form of the viewgraphs. The following subject areas are covered: satellite control network; current and new approaches to range scheduling; MITRE tasking; RSA features; RSA display; constraint based analytic capability; RSA architecture; and RSA benefits.

  1. Final report on the key comparison, CCM.P-K15 in the pressure range from 1.0 × 10-4 Pa to 1.0 Pa

    Science.gov (United States)

    Wuethrich, Christian; Arai, Kenta; Bergoglio, Mercede; Fedchak, James A.; Jousten, Karl; Hong, Seung Soo; Torres Guzman, Jorge

    2017-01-01

    The comparison CCM.P-K15 is a key comparison in pressure involving six laboratories in three regional metrological organizations (RMO). The measurand of the comparison is the accommodation coefficient of two spinning rotating gauge characterized in nitrogen from 0.1 mPa up to 1.0 Pa. The two transfer standards were circulated from November 2009 until March 2011. The circulation consisted of three loops, one for each RMO, and a new calibration by the pilot be-tween each loop. The stability of one of the transfer standards was poor and was worse than expected based on the previous history of the transfer standard while the other transfer standard demonstrated good stability while circulated in Europe and America and a fair stability while circulated in Asia. All the participants demonstrated equivalence to the definition of pressure in their respective primary standards. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

  2. Home range and travels

    Science.gov (United States)

    Stickel, L.F.; King, John A.

    1968-01-01

    The concept of home range was expressed by Seton (1909) in the term 'home region,' which Burr (1940, 1943) clarified with a definition of home range and exemplified in a definitive study of Peromyscus in the field. Burt pointed out the ever-changing characteristics of home-range area and the consequent absence of boundaries in the usual sense--a finding verified by investigators thereafter. In the studies summarized in this paper, sizes of home ranges of Peromyscus varied within two magnitudes, approximately from 0.1 acre to ten acres, in 34 studies conducted in a variety of habitats from the seaside dunes of Florida to the Alaskan forests. Variation in sizes of home ranges was correlated with both environmental and physiological factors; with habitat it was conspicuous, both in the same and different regions. Food supply also was related to size of home range, both seasonally and in relation to habitat. Home ranges generally were smallest in winter and largest in spring, at the onset of the breeding season. Activity and size also were affected by changes in weather. Activity was least when temperatures were low and nights were bright. Effects of rainfall were variable. Sizes varied according to sex and age; young mice remained in the parents' range until they approached maturity, when they began to travel more widely. Adult males commonly had larger home ranges than females, although there were a number of exceptions. An inverse relationship between population density and size of home range was shown in several studies and probably is the usual relationship. A basic need for activity and exploration also appeared to influence size of home range. Behavior within the home range was discussed in terms of travel patterns, travels in relation to home sites and refuges, territory, and stability of size of home range. Travels within the home range consisted of repeated use of well-worn trails to sites of food, shelter, and refuge, plus more random exploratory travels

  3. Adolescents previously involved in Satanism experiencing mental health problems

    OpenAIRE

    H. Heathcote

    1999-01-01

    No research has previously been done regarding the phenomenon of adolescents who have previously been involved in Satanism and who experience obstacles in their strive for mental health. Adolescents previously involved in Satanism present behavioral problems like aggressive outbursts, depression, “ psychosis” or suicide attempts, that could lead to suicide. In the phenomenonanalysis semi-structured, phenomenological interviews were performed with the respondents and their parents. The respond...

  4. Long range image enhancement

    CSIR Research Space (South Africa)

    Duvenhage, B

    2015-11-01

    Full Text Available and Vision Computing, Auckland, New Zealand, 23-24 November 2015 Long Range Image Enhancement Bernardt Duvenhage Council for Scientific and Industrial Research South Africa Email: bduvenhage@csir.co.za Abstract Turbulent pockets of air...

  5. SNOWY RANGE WILDERNESS, WYOMING.

    Science.gov (United States)

    Houston, Robert S.; Bigsby, Philip R.

    1984-01-01

    A mineral survey of the Snowy Range Wilderness in Wyoming was undertaken and was followed up with more detailed geologic and geochemical surveys, culminating in diamond drilling of one hole in the Snowy Range Wilderness. No mineral deposits were identified in the Snowy Range Wilderness, but inasmuch as low-grade uranium and associated gold resources were identified in rocks similar to those of the northern Snowy Range Wilderness in an area about 5 mi northeast of the wilderness boundary, the authors conclude that the northern half of the wilderness has a probable-resource potential for uranium and gold. Closely spaced drilling would be required to completely evaluate this mineral potential. The geologic terrane precludes the occurrence of fossil fuels.

  6. Atlantic Test Range (ATR)

    Data.gov (United States)

    Federal Laboratory Consortium — ATR controls fully-instrumented and integrated test ranges that provide full-service support for cradle-to-grave testing. Airspace and surface target areas are used...

  7. Light Detection And Ranging

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — LiDAR (Light Detection and Ranging) discrete-return point cloud data are available in the American Society for Photogrammetry and Remote Sensing (ASPRS) LAS format....

  8. On Range of Skill

    DEFF Research Database (Denmark)

    Hansen, Thomas Dueholm; Miltersen, Peter Bro; Sørensen, Troels Bjerre

    2008-01-01

    is a small number, but only gave heuristic arguments for this. In this paper, we provide the first methods for rigorously estimating the Range of Skill of a given game. We provide some general, asymptotic bounds that imply that the Range of Skill of a perfectly balanced game tree is almost exponential in its......At AAAI'07, Zinkevich, Bowling and Burch introduced the Range of Skill measure of a two-player game and used it as a parameter in the analysis of the running time of an algorithm for finding approximate solutions to such games. They suggested that the Range of Skill of a typical natural game...... size (and doubly exponential in its depth). We also provide techniques that yield concrete bounds for unbalanced game trees and apply these to estimate the Range of Skill of Tic-Tac-Toe and Heads-Up Limit Texas Hold'em Poker. In particular, we show that the Range of Skill of Tic-Tac-Toe is more than...

  9. Direct measurement of additional Ar-H2O vibration-rotation-tunneling bands in the millimeter-submillimeter range

    Science.gov (United States)

    Zou, Luyao; Widicus Weaver, Susanna L.

    2016-06-01

    Three new weak bands of the Ar-H2O vibration-rotation-tunneling spectrum have been measured in the millimeter wavelength range. These bands were predicted from combination differences based on previously measured bands in the submillimeter region. Two previously reported submillimeter bands were also remeasured with higher frequency resolution. These new measurements allow us to obtain accurate information on the Coriolis interaction between the 101 and 110 states. Here we report these results and the associated improved molecular constants.

  10. 14 CFR 47.33 - Aircraft not previously registered anywhere.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Aircraft not previously registered anywhere... TRANSPORTATION AIRCRAFT AIRCRAFT REGISTRATION Certificates of Aircraft Registration § 47.33 Aircraft not previously registered anywhere. (a) A person who is the owner of an aircraft that has not been registered...

  11. 2 CFR 220.40 - Relationship to previous issuance.

    Science.gov (United States)

    2010-01-01

    ... 2 Grants and Agreements 1 2010-01-01 2010-01-01 false Relationship to previous issuance. 220.40 Section 220.40 Grants and Agreements OFFICE OF MANAGEMENT AND BUDGET CIRCULARS AND GUIDANCE Reserved COST PRINCIPLES FOR EDUCATIONAL INSTITUTIONS (OMB CIRCULAR A-21) § 220.40 Relationship to previous issuance. (a...

  12. 2 CFR 230.45 - Relationship to previous issuance.

    Science.gov (United States)

    2010-01-01

    ... 2 Grants and Agreements 1 2010-01-01 2010-01-01 false Relationship to previous issuance. 230.45 Section 230.45 Grants and Agreements OFFICE OF MANAGEMENT AND BUDGET CIRCULARS AND GUIDANCE Reserved COST PRINCIPLES FOR NON-PROFIT ORGANIZATIONS (OMB CIRCULAR A-122) § 230.45 Relationship to previous issuance. (a...

  13. 2 CFR 1.215 - Relationship to previous issuances.

    Science.gov (United States)

    2010-01-01

    ... 2 Grants and Agreements 1 2010-01-01 2010-01-01 false Relationship to previous issuances. 1.215 Section 1.215 Grants and Agreements ABOUT TITLE 2 OF THE CODE OF FEDERAL REGULATIONS AND SUBTITLE A Introduction toSubtitle A § 1.215 Relationship to previous issuances. Although some of the guidance was...

  14. 75 FR 76056 - FEDERAL REGISTER CITATION OF PREVIOUS ANNOUNCEMENT:

    Science.gov (United States)

    2010-12-07

    ... From the Federal Register Online via the Government Publishing Office SECURITIES AND EXCHANGE COMMISSION Sunshine Act Meeting FEDERAL REGISTER CITATION OF PREVIOUS ANNOUNCEMENT: STATUS: Closed meeting. PLACE: 100 F Street, NE., Washington, DC. DATE AND TIME OF PREVIOUSLY ANNOUNCED MEETING: Thursday...

  15. Detection of a second novel gammaherpesvirus in a free-ranging koala (Phascolarctos cinereus).

    Science.gov (United States)

    Vaz, Paola; Whiteley, Pam L; Wilks, Colin R; Browning, Glenn F; Gilkerson, James R; Ficorilli, Nino; Devlin, Joanne M

    2012-01-01

    A second novel gammaherpesvirus was detected in a free-ranging koala (Phascolarctos cinereus) shown previously to be infected with phascolarctid herpesvirus 1. Analysis of the DNA polymerase gene showed that the virus was genetically distinct from all known gammaherpesviruses. This is the first reported dual gammaherpesvirus infection in an Australian marsupial.

  16. Spectroscopy of asteroid pairs - new observations support previous conclusions

    Science.gov (United States)

    Polishook, David; Oszkiewicz, Dagmara Anna; None Kwiatkowski, Tomasz

    2015-08-01

    Asteroid pairs were split due to fast rotation of a strengthless body. Study them can reveal fundamental principles in asteroid interiors and evolution. We continue our spectroscopic survey of asteroid pairs in the near-IR range (IRTF) and work on completing the spectral coverage in the visible wavelength (SALT, NOT).Our new observations support our previous conclusions (Polishook et al. 2014):1. Primary and secondary members have very similar reflectance spectra supporting the claim that every pair originated from a single progenitor. We measured 2 more pairs that present the same taxonomy (4905-7813, 15107-291188). This increases to 22 the number of asteroid pairs with spectral similarities and supports the claim of a single progenitor for each pair to a significance of over 5 sigma.2. Rotational fission is not a function of the asteroid composition rather the asteroid’s structure. We present new reflectance spectra of S- and C-complex pairs that differ in their composition.3. Some asteroid pairs present spectral parameters that imply a fresh, non-weathered surface. This includes spectral slope, and a deep and wide absorption band at 1 micron. Among these, the asteroid 8306 can now be re-classified as a Q-type asteroid, a common class in the near-Earth environment, but rare in the main belt. 8306 is the 4th Q-type discovered within asteroid pairs (all locate in the main belt).4. A secondary member of an asteroid pair composed of ordinary chondrite (S-complex) might present a reflectance spectrum with lower spectral slope compared to its primary member. This is seen in the new measured reflectance spectrum of secondary 291188). This result supports the theory of Jacobson & Scheeres (2011) of continuous disintegration of the secondaries while still in the vicinity of their primaries.5. With time, the fresh surface becomes weathered. Dynamical calculations limit the disintegration time of the progenitor of the pair 4905-7813 to 1.65 millions years ago, what makes

  17. Global patterns of geographic range size in birds.

    Directory of Open Access Journals (Sweden)

    C David L Orme

    2006-07-01

    Full Text Available Large-scale patterns of spatial variation in species geographic range size are central to many fundamental questions in macroecology and conservation biology. However, the global nature of these patterns has remained contentious, since previous studies have been geographically restricted and/or based on small taxonomic groups. Here, using a database on the breeding distributions of birds, we report the first (to our knowledge global maps of variation in species range sizes for an entire taxonomic class. We show that range area does not follow a simple latitudinal pattern. Instead, the smallest range areas are attained on islands, in mountainous areas, and largely in the southern hemisphere. In contrast, bird species richness peaks around the equator, and towards higher latitudes. Despite these profoundly different latitudinal patterns, spatially explicit models reveal a weak tendency for areas with high species richness to house species with significantly smaller median range area. Taken together, these results show that for birds many spatial patterns in range size described in geographically restricted analyses do not reflect global rules. It remains to be discovered whether global patterns in geographic range size are best interpreted in terms of geographical variation in species assemblage packing, or in the rates of speciation, extinction, and dispersal that ultimately underlie biodiversity.

  18. Radio pill antenna range test

    Science.gov (United States)

    Cummins, W. F.; Kane, R. J.

    1992-05-01

    In order to investigate the potential of a proposed 'radio pill' beacon transmitter, a range test experiment was devised and carried out in the VHF frequency range. Calculations and previous work indicated that optimum sensitivity and, thus, distance would be obtained in this frequency range provided body radio-frequency (RF) absorption was not too great. A ferrite-core loop antenna is compatible with a pill geometry and has better radiation efficiency than an air core loop. The ferrite core may be a hollow cylinder with the electronics and batteries placed inside. However, this range test was only concerned with experimentally developing test range data on the ferrite core antenna itself. A one turn strap loop was placed around a 9.5 mm diameter by 18.3 mm long stack of ferrite cores. This was coupled to a 50 Omega transmission line by 76 mm of twisted pair line and a capacitive matching section. This assembly was excited by a signal generator at output levels of -10 to +10 dBm. Signals were received on a VHF receiver and tape recorder coupled to a 14 element, circularly polarized Yagi antenna at a height of 2.5 m. Field strength measurements taken at ranges of 440, 1100, and 1714 m. Maximum field strengths referenced to 0 dBm transmitter level were -107 to -110 dB at 440 m, -124 to -127 dBm at 1100 m, and -116 to -119 dBm at 1714 m when the antenna cylinder was horizontal. Field strengths with a vertical antenna were about 6 dB below these values. The latter transmit site was elevated and had a clear line-of-site path to the receiving site. The performance of this test antenna was better than that expected from method-of-moment field calculations. When this performance data is scaled to a narrow bandwidth receiving system, ground level receiving ranges of a few to 10 km can be expected. Clear line-of-sight ranges where either or both the transmitter and receiver are elevated could vary from several km to 100 km.

  19. Additions to generating capacity 1978--1987 for the contiguous United States: as projected by the Regional Electric Reliability Councils in their April 1, 1978 long-range coordinated planning reports to the Department of Energy

    Energy Technology Data Exchange (ETDEWEB)

    1978-09-15

    Comparison of the 1978 projections of the Reliability Councils with those made the previous year indicates three major changes in electric utility planning: (1) a reduction in total capacity additions for the 10-year planning period, (2) a significant decrease in nuclear additions, and (3) a shift from oil and gas to coal as a source of primary energy. Nuclear capacity continues to far overshadow fossil-fuel capacity in the unit-size range 1000 MW and up, with the reverse true for unit sizes less than 1000 MW. Although the total 10-year new-unit capacity drops from 326,624 MW (1977 to 1986) to 308,017 (1978 to 1987), new capacity planned that would use coal as a primary energy source increases from 136,763 MW to 146,206 MW. Nuclear capacity, in terms of total new units projected for the two 10-year periods, decreases from 130,532 MW to 116,177 MW, and capacity with oil as the primary source drops from 32,837 MW to 21,072 MW. For 1977 to 1986, no capacity was planned with oil as a primary source and coal as an alternate fuel but for 1978 to 1987, 1220 MW of such capacity is projected. Therefore, the total new capacity projected that could use coal as a fuel (primary or alternate) is 147,426 MW. In addition, one 700-MW unit is planned for which the primary fuel will be a blend of coal and refuse. There is a decrease in the capacity planned that would use natural gas a a primary source, from 2,089 MW in 1977 to 1986 to 502 MW in 1978 to 1987.

  20. Range Selection and Median

    DEFF Research Database (Denmark)

    Jørgensen, Allan Grønlund; Larsen, Kasper Green

    2011-01-01

    that supports queries in constant time, needs n1+ (1) space. For data structures that uses n logO(1) n space this matches the best known upper bound. Additionally, we present a linear space data structure that supports range selection queries in O(log k= log log n + log log n) time. Finally, we prove that any...

  1. Electric vehicles: Driving range

    Science.gov (United States)

    Kempton, Willett

    2016-09-01

    For uptake of electric vehicles to increase, consumers' driving-range needs must be fulfilled. Analysis of the driving patterns of personal vehicles in the US now shows that today's electric vehicles can meet all travel needs on almost 90% of days from a single overnight charge.

  2. Induction of labour in women with one previous caesarean section.

    Science.gov (United States)

    Gupta, P; Elmardi, A; Bathula, U; Chandru, S; Charlesworth, D

    2011-01-01

    We conducted a postal survey of NHS obstetric consultants working in England regarding their own practice and views on induction of labour in women with one previous caesarean section. Out of 480 consultant obstetricians across England, 322 replied, giving a response rate of 67%. Our survey has revealed a wide variation in practice of consultants across England, regarding induction of labour at term or post-term in women with one previous caesarean section. Hence, we feel that there is a need for a national audit of induction of labour in women with one previous caesarean section, with uterine rupture following induction of labour in such women as an auditable standard.

  3. Adolescents previously involved in Satanism experiencing mental health problems

    Directory of Open Access Journals (Sweden)

    H Heathcote

    1999-09-01

    Full Text Available No research has previously been done regarding the phenomenon of adolescents who have previously been involved in Satanism and who experience obstacles in their strive for mental health. Adolescents previously involved in Satanism present behavioral problems like aggressive outbursts, depression, “ psychosis” or suicide attempts, that could lead to suicide. In the phenomenonanalysis semi-structured, phenomenological interviews were performed with the respondents and their parents. The respondents were requested to write a naïve sketch about their life. After completion of the data-control, guidelines for nursing staff were set.

  4. GRB Flares: A New Detection Algorithm, Previously Undetected Flares, and Implications on GRB Physics

    Science.gov (United States)

    Swenson, Craig A.; Roming, P.

    2013-04-01

    Flares in GRB light curves have been observed since shortly after the discovery of the first GRB afterglow. However, it was not until the launch of the Swift satellite that it was realized how common flares are, appearing in nearly 50% of all X-ray afterglows as observed by the XRT instrument. The majority of these observed X-ray flares are easily distinguishable by eye and have been measured to have up to as much fluence as the original prompt emission. Through studying large numbers of these X-ray flares it has been determined that they likely result from a distinct emission source different than that powering the GRB afterglow. These findings could be confirmed if similar results were found using flares in other energy ranges. However, until now, the UVOT instrument on Swift seemed to have observed far fewer flares in the uv/optical than were seen in the X-ray. This was primarily due to poor sampling and data being spread across multiple filters, but a new optimal co-addition and normalization of the UVOT data has allowed us to search for flares in the uv/optical that have previously gone undetected. Using a flare finding algorithm based on the Bayesian Information Criterion, we have analyzed the light curves in the Second UVOT GRB Catalog and present the finding of at least 118 unique flares detected in 68 GRB afterglows. We have also analyzed the XRT observed afterglows from the same time period using the flare finding algorithm, in an attempt to find smaller, previously unreported X-ray flares. Here we report our initial findings of this analysis on the X-ray afterglows and the number of flares detected. The cross-correlation of these two flare catalogs will better constrain the precise origin of flares, and also lead to a better understanding of the nature of the central engine, one of the likely origin candidates.

  5. Ulcerative colitis may not necessarily be rare as previously thought ...

    African Journals Online (AJOL)

    Ulcerative colitis may not necessarily be rare as previously thought in tropical and subtropical Africa. With increasing westernized life style, greater utilization and accessibility to modern medical practice,availability of tertiary level health care di.

  6. Influence of previous participation in physical activity on its ...

    African Journals Online (AJOL)

    ... participation can influence perceptions of PA among the students. Physical activity promotion programmes should consider the role of these factors which should be emphasised from childhood. Keywords: physical activity, students, perceived benefits, perceived barriers, previous participation, sedentary lifestyle, Rwanda

  7. Is Previous Respiratory Disease a Risk Factor for Lung Cancer?

    NARCIS (Netherlands)

    Denholm, Rachel; Schüz, Joachim; Straif, Kurt; Stücker, Isabelle; Jöckel, Karl-Heinz; Brenner, Darren R; De Matteis, Sara; Boffetta, Paolo; Guida, Florence; Brüske, Irene; Wichmann, Heinz-Erich; Landi, Maria Teresa; Caporaso, Neil; Siemiatycki, Jack; Ahrens, Wolfgang; Pohlabeln, Hermann; Zaridze, David; Field, John K; McLaughlin, John; Demers, Paul; Szeszenia-Dabrowska, Neonila; Lissowska, Jolanta; Rudnai, Peter; Fabianova, Eleonora; Dumitru, Rodica Stanescu; Bencko, Vladimir; Foretova, Lenka; Janout, Vladimir; Kendzia, Benjamin; Peters, Susan; Behrens, Thomas; Vermeulen, Roel; Brüning, Thomas; Kromhout, Hans; Olsson, Ann

    2014-01-01

    Rationale: Previous respiratory diseases have been associated with increased risk of lung cancer. Respiratory conditions often co-occur and few studies have investigated multiple conditions simultaneously. Objectives: Investigate lung cancer risk associated with chronic bronchitis, emphysema,

  8. Tubal anastomosis after previous sterilization: a systematic review.

    Science.gov (United States)

    van Seeters, Jacoba A H; Chua, Su Jen; Mol, Ben W J; Koks, Carolien A M

    2017-05-01

    Female sterilization is one of the most common contraceptive methods. A small number of women, however, opt for reversal of sterilization procedures after they experience regret. Procedures can be performed by laparotomy or laparoscopy, with or without robotic assistance. Another commonly utilized alternative is IVF. The choice between surgery and IVF is often influenced by reimbursement politics for that particular geographic location. We evaluated the fertility outcomes of different surgical methods available for the reversal of female sterilization, compared these to IVF and assessed the prognostic factors for success. Two search strategies were employed. Firstly, we searched for randomized and non-randomized clinical studies presenting fertility outcomes of sterilization reversal up to July 2016. Data on the following outcomes were collected: pregnancy rate, ectopic pregnancy rate, cost of the procedure and operative time. Eligible study designs included prospective or retrospective studies, randomized controlled trials, cohort studies, case-control studies and case series. No age restriction was applied. Exclusion criteria were patients suffering from tubal infertility from any other reason (e.g. infection, endometriosis and adhesions from previous surgery) and studies including sterilization reversal procedures were then evaluated: female age, BMI and duration and method of sterilization. Secondly, we searched for randomized and non-randomized clinical studies that compared reversal of sterilization to IVF and evaluated them for pregnancy outcomes and cost effectiveness. We included 37 studies that investigated a total of 10 689 women. No randomized controlled trials were found. Most studies were retrospective cohort studies of a moderate quality. The pooled pregnancy rate after sterilization reversal was 42-69%, with heterogeneity seen from the different methods utilized. The reported ectopic pregnancy rate was 4-8%. The only prognostic factor affecting the

  9. [Surgery for bronchial carcinoma after treatment of a previous cancer].

    Science.gov (United States)

    Mordant, P; Pages, P-B; Foucault, C; Badia, A; Fabre, E; Dujon, A; Le Pimpec Barthes, F; Riquet, M

    2013-05-01

    The increase in the number of cancer survivors, together with the improvement of their follow-up, lead to the frequent diagnosis of resectable non-small cell lung cancer (NSCLC) in patients with history of previous malignancy. We sought to analyse the outcomes of these patients. Patients undergoing surgical resection for NSCLC between January 1980 and December 2009 were retrospectively reviewed. For each patient, the presence of previous malignancy was noted, and classified into five groups: oro-pharyngeal cancer, lung cancer, haematopoietic malignancy, other organ malignancy, and more than two cancers. The overall population included 5846 patients. Among them, 1243 (21%) had a history of previous malignancy, of whom 383 (31%) presented with synchronous cancer. Patients with history of previous malignancy were more often female, older, with more adenocarcinomas, more limited disease, less pneumonectomies, but higher postoperative morbidity and mortality. Overall survival was worse in patients with a history of previous malignancy than in patients without (median, 5 and 10 year: 33 months, 34.3%, 17.8% versus 47 months, 44.6%, 28.8%). A history of previous malignancy impacted significantly the prognosis of patients operated on for limited NSCLC. However, only surgical resection led to improved long-term survival at 5 years. Copyright © 2013 SPLF. Published by Elsevier Masson SAS. All rights reserved.

  10. Long-term follow-up of patients with previous myocarditis using radionuclide ventriculography.

    Science.gov (United States)

    Das, S K; Colfer, H T; Pitt, B

    1985-01-01

    A prospective long-term follow-up study is reported of 18 of 19 patients who survived a bout of presumed myocarditis 6-136 months (average 54 months) previously. The study included 14 males and four females, ranging from 27 to 63 years of age (mean, 44 years). Chest X-ray, ECG, echocardiogram, and resting and exercise radionuclide ventricular ejection fraction (RNVEF) for assessment of ventricular function were evaluated at follow-up. Resting and exercise RNVEF from seven control subjects were evaluated for comparison. Residual abnormalities were noted in chest X-ray (16%), echocardiogram (30%), and ECG (55%) in these predominantly asymptomatic patients (17/18 or 95%). The resting RNVEF (mean +/- SD) for the myocarditis group versus controls were 0.57 +/- 0.1 and 0.65 +/- 0.1 (P = NS), respectively. The exercise RNVED for the myocarditis group versus controls were 0.56 +/- 0.1 and 0.74 +/- 0.05 (P less than 0.01), respectively. Abnormal resting RNVEF was noted in six (33%) and exercise RNVEF in 14 (77%) patients in the myocarditis group. Two patients with abnormal exercise RNVEF subsequently developed findings consistent with dilated cardiomyopathy. It is unclear as to whether the abnormal ventricular function may serve as a marker for future development of dilated cardiomyopathy.

  11. Persistence of mercury-induced motor and sensory neurotoxicity: systematic review of workers previously exposed to mercury vapor.

    Science.gov (United States)

    Fields, Cheryl A; Borak, Jonathan; Louis, Elan D

    2017-11-01

    Elemental mercury (Hg0) is a well-recognized neurotoxicant, but it is uncertain whether and for how long its neurotoxicity persists. Among studies that evaluated previously-exposed workers, only one examined workers during and also years after exposure had ceased. The objective of this review is to create a series of 'synthetic' longitudinal studies to address the question of persistence of Hg0 neurotoxicity in occupationally exposed workers. We systematically reviewed studies describing objective motor and sensory effects in previously-exposed mercury workers. Data from physical examination (PE), neurobehavioral (NB) tests, and electrophysiological studies (EPS) were extracted into structured tables and examined for their consistency and dose-relatedness and then compared with the corresponding results from studies of currently exposed workers. We identified six cohorts that described neurological findings in 1299 workers, examined an average of 4.8-30 years after the cessation of exposure. Historical group mean UHg levels ranged from 23 to >500 μg/L, with UHg levels >6000 μg/L in some individuals. Overall, few findings were significant; most were inconsistent across the previous-exposure studies, and in comparisons between studies of previously and currently exposed workers. The results of this systematic review indicate that Hg0-related neurotoxic effects detectable on PE, NB testing, and EPS are substantially reversed over time. To the extent that such effects do persist, they are reported principally in workers who have had very high-dose exposures. In addition, based on the limited available data, those effects reported to persist have been described as having little or no functional significance.

  12. Prevalence and Correlates of Drinking Behaviors of Previously Deployed Military Personnel and Matched Civilian Population

    Science.gov (United States)

    Ramchand, Rajeev; Miles, Jeremy; Schell, Terry; Jaycox, Lisa; Marshall, Grant N.; Tanielian, Terri

    2011-01-01

    We examined drinking behaviors (frequency of use, quantity of use, and frequency of binge drinking) and correlates of frequency of use and binge drinking in a representative sample of previously deployed personnel from the US military (n = 1887). Drinking behaviors were compared with a matched sample of adults in U.S. households (n = 17,533). Comparable patterns of alcohol consumption were reported in both samples: 70% of previously deployed personnel and 69% of US adults reported drinking alcohol in the past 30 days though, civilians drank on average more drinks on the days that they drank than did previously deployed military personnel. Regression analyses indicated that among previously deployed military personnel, deployment-related experiences (e.g., combat-related traumas) and psychological distress (e.g., symptoms associated with posttraumatic stress disorder) were associated with frequency of drinking behaviors. We discuss the implication of our findings for developing interventions to modify drinking behaviors for military personnel. PMID:25324594

  13. Dapsone-induced methemoglobinemia in renal transplant recipients: more prevalent than previously thought.

    Science.gov (United States)

    Mitsides, N; Green, D; Middleton, R; New, D; Lamerton, E; Allen, J; Redshaw, J; Chadwick, P R; Subudhi, C P K; Wood, G

    2014-02-01

    After an outbreak of Pneumocystis pneumonia (PCP) in our nephrology unit, dapsone was used as the second-line chemoprophylactic agent. Dapsone is the most common cause of drug-induced methemoglobinemia (MHb). Its prevalence is poorly described in the renal transplant population. Because dapsone is excreted by the kidneys, we hypothesized that the rate of MHb in these patients would be higher than previously reported. We aimed to describe the demographics, risk factors, and presenting features of MHb in these renal transplant patients. Twenty-six transplant recipients commenced on dapsone for chemoprophylaxis against PCP from February to September 2011. All patients had normal glucose-6-phosphate dehydrogenase levels before treatment. Characteristics of patients with MHb were compared with those of the rest of the cohort to determine potential risk factors. Twelve (46%) patients developed MHb (levels 6.4 ± 4.1%). Six (50%) of the patients with MHb were asymptomatic on presentation. Cases had a mean drop in hemoglobin of 19 ± 7%. MHb led to five admissions (median length of stay 5 days, range 1-10 days). MHb level showed a strong correlation with the length of stay (correlation coefficient 0.762, P = 0.002). This is the highest reported prevalence of MHb, to our knowledge, in patients receiving dapsone, and its use led to significant hospitalization in this population. This study raises concerns about the use of dapsone as chemoprophylaxis in renal transplant recipients. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  14. Coma after greater occipital nerve blockade in a patient with previous posterior fossa surgery.

    Science.gov (United States)

    Sprenger, Till; Seifert, Christian L

    2013-03-01

    We here report the case of a patient who previously underwent posterior fossa surgery and was later treated with greater occipital nerve blockade for unilateral facial pain. The patient went into coma immediately post-injection but made a full recovery without sequelae after intensive care treatment. Physicians should be aware of the risks of greater occipital nerve blockade after previous posterior fossa craniotomy. © 2012 American Headache Society.

  15. Cache-Oblivious Planar Orthogonal Range Searching and Counting

    DEFF Research Database (Denmark)

    Arge, Lars; Brodal, Gerth Stølting; Fagerberg, Rolf

    2005-01-01

    present the first cache-oblivious data structure for planar orthogonal range counting, and improve on previous results for cache-oblivious planar orthogonal range searching. Our range counting structure uses O(Nlog2 N) space and answers queries using O(logB N) memory transfers, where B is the block...... size of any memory level in a multilevel memory hierarchy. Using bit manipulation techniques, the space can be further reduced to O(N). The structure can also be modified to support more general semigroup range sum queries in O(logB N) memory transfers, using O(Nlog2 N) space for three-sided queries...... and O(Nlog22 N/log2log2 N) space for four-sided queries. Based on the O(Nlog N) space range counting structure, we develop a data structure that uses O(Nlog2 N) space and answers three-sided range queries in O(logB N+T/B) memory transfers, where T is the number of reported points. Based...

  16. Frequency and clinical significance of previously undetected incidental findings detected on computed tomography simulation scans for breast cancer patients.

    Science.gov (United States)

    Nakamura, Naoki; Tsunoda, Hiroko; Takahashi, Osamu; Kikuchi, Mari; Honda, Satoshi; Shikama, Naoto; Akahane, Keiko; Sekiguchi, Kenji

    2012-11-01

    To determine the frequency and clinical significance of previously undetected incidental findings found on computed tomography (CT) simulation images for breast cancer patients. All CT simulation images were first interpreted prospectively by radiation oncologists and then double-checked by diagnostic radiologists. The official reports of CT simulation images for 881 consecutive postoperative breast cancer patients from 2009 to 2010 were retrospectively reviewed. Potentially important incidental findings (PIIFs) were defined as any previously undetected benign or malignancy-related findings requiring further medical follow-up or investigation. For all patients in whom a PIIF was detected, we reviewed the clinical records to determine the clinical significance of the PIIF. If the findings from the additional studies prompted by a PIIF required a change in management, the PIIF was also recorded as a clinically important incidental finding (CIIF). There were a total of 57 (6%) PIIFs. The 57 patients in whom a PIIF was detected were followed for a median of 17 months (range, 3-26). Six cases of CIIFs (0.7% of total) were detected. Of the six CIIFs, three (50%) cases had not been noted by the radiation oncologist until the diagnostic radiologist detected the finding. On multivariate analysis, previous CT examination was an independent predictor for PIIF (p = 0.04). Patients who had not previously received chest CT examinations within 1 year had a statistically significantly higher risk of PIIF than those who had received CT examinations within 6 months (odds ratio, 3.54; 95% confidence interval, 1.32-9.50; p = 0.01). The rate of incidental findings prompting a change in management was low. However, radiation oncologists appear to have some difficulty in detecting incidental findings that require a change in management. Considering cost, it may be reasonable that routine interpretations are given to those who have not received previous chest CT examinations within 1 year

  17. Corneal biomechanical properties in eyes with no previous surgery, with previous penetrating keratoplasty and with deep anterior lamellar keratoplasty.

    Science.gov (United States)

    Acar, Banu Torun; Akdemir, Mehmet Orcun; Acar, Suphi

    2013-01-01

    To compare the biomechanical properties of the cornea in eyes with no previous surgery, with keratoconus with previous penetrating keratoplasty (PK) and with keratoconus with previous deep anterior lamellar keratoplasty (DALK) using the Reichert Ocular Response Analyzer (ORA). One hundred twenty eyes of 120 patients were included in this prospective comparative study. Forty eyes were with no previous ocular surgery (group 1), 40 eyes were with previous PK for keratoconus (group 2), and 40 eyes were with previous DALK for keratoconus (group 3). Corneal hysteresis (CH) and the corneal resistance factor (CRF) were measured with ORA. The CH and CRF values in group 2 were significantly lower than in group 1 and group 3 (p = 0.001). The CH and CRF values were similar in group 1 and group 3. There was no statistically significant difference between group 1 and 3. Although the post-PK keratoconus cornea has weaker biomechanical properties, post-DALK keratoconus cornea is similar to normal cornea. A cornea weakened by keratoconus can be strengthened with lamellar keratoplasty.

  18. Long-range antigravity

    Energy Technology Data Exchange (ETDEWEB)

    Macrae, K.I.; Riegert, R.J. (Maryland Univ., College Park (USA). Center for Theoretical Physics)

    1984-10-01

    We consider a theory in which fermionic matter interacts via long-range scalar, vector and tensor fields. In order not to be in conflict with experiment, the scalar and vector couplings for a given fermion must be equal, as is natural in a dimensionally reduced model. Assuming that the Sun is not approximately neutral with respect to these new scalar-vector charges, and if the couplings saturate the experimental bounds, then their strength can be comparable to that of gravity. Scalar-vector fields of this strength can compensate for a solar quadrupole moment contribution to Mercury's anomalous perihelion precession.

  19. Combination treatment with mirabegron and solifenacin in patients with overactive bladder: exploratory responder analyses of efficacy and evaluation of patient-reported outcomes from a randomized, double-blind, factorial, dose-ranging, Phase II study (SYMPHONY).

    Science.gov (United States)

    Abrams, P; Kelleher, C; Staskin, D; Kay, R; Martan, A; Mincik, I; Newgreen, D; Ridder, A; Paireddy, A; van Maanen, R

    2017-05-01

    This large dose-ranging study explored the benefits of different combinations of mirabegron and solifenacin on health-related quality of life (HRQoL), based on patient-reported outcomes (PROs), and patients ('responders') achieving clinically meaningful improvements in efficacy and HRQoL. SYMPHONY (NCT01340027) was a Phase II, placebo- and monotherapy-controlled, dose-ranging, 12-week trial. Adult patients with overactive bladder (OAB) for ≥3 months were randomized to 1 of 12 groups: 6 combination (solifenacin 2.5/5/10 mg + mirabegron 25/50 mg), 5 monotherapy (solifenacin 2.5/5/10 mg, or mirabegron 25/50 mg), or placebo. Change from baseline to end of treatment was assessed, versus placebo and solifenacin 5 mg in: PROs (OAB-q [Symptom Bother/total HRQoL] and Patient Perception of Bladder Condition score), and responders achieving minimally important differences (MIDs) in PROs and predetermined clinically meaningful improvements in efficacy (e.g. <8 micturitions/24 h). Changes in PROs and responders were analysed using an ANCOVA model and logistic regression, respectively. The Full Analysis Set included 1278 patients. Combination therapy of solifenacin 5/10 mg + mirabegron 25/50 mg significantly improved PROs versus solifenacin 5 mg and placebo, and significantly more responders achieved MIDs in PROs and efficacy. Micturition frequency normalization was approximately twofold greater with 10 + 25 mg (OR 2.06 [95 % CI 1.11, 3.84; p = 0.023]) and 5 + 50 mg (OR 1.91 [95 % CI 1.14, 3.21; p = 0.015]) versus solifenacin 5 mg. Combining mirabegron 25/50 mg and solifenacin 5/10 mg improves objective and subjective efficacy outcomes compared with placebo or solifenacin 5 mg.

  20. Nuclear-spin-independent short-range three-body physics in ultracold atoms.

    Science.gov (United States)

    Gross, Noam; Shotan, Zav; Kokkelmans, Servaas; Khaykovich, Lev

    2010-09-03

    We investigate three-body recombination loss across a Feshbach resonance in a gas of ultracold 7Li atoms prepared in the absolute ground state and perform a comparison with previously reported results of a different nuclear-spin state [N. Gross, Phys. Rev. Lett. 103, 163202 (2009)]. We extend the previously reported universality in three-body recombination loss across a Feshbach resonance to the absolute ground state. We show that the positions and widths of recombination minima and Efimov resonances are identical for both states which indicates that the short-range physics is nuclear-spin independent.

  1. Ranging Behaviour of Commercial Free-Range Broiler Chickens 2: Individual Variation.

    Science.gov (United States)

    Taylor, Peta S; Hemsworth, Paul H; Groves, Peter J; Gebhardt-Henrich, Sabine G; Rault, Jean-Loup

    2017-07-20

    Little is known about broiler chicken ranging behaviour. Previous studies have monitored ranging behaviour at flock level but whether individual ranging behaviour varies within a flock is unknown. Using Radio Frequency Identification technology, we tracked 1200 individual ROSS 308 broiler chickens across four mixed sex flocks in two seasons on one commercial farm. Ranging behaviour was tracked from first day of range access (21 days of age) until 35 days of age in winter flocks and 44 days of age in summer flocks. We identified groups of chickens that differed in frequency of range visits: chickens that never accessed the range (13 to 67% of tagged chickens), low ranging chickens (15 to 44% of tagged chickens) that accounted for <15% of all range visits and included chickens that used the range only once (6 to 12% of tagged chickens), and high ranging chickens (3 to 9% of tagged chickens) that accounted for 33 to 50% of all range visits. Males spent longer on the range than females in winter (p < 0.05). Identifying the causes of inter-individual variation in ranging behaviour may help optimise ranging opportunities in free-range systems and is important to elucidate the potential welfare implications of ranging.

  2. High prevalence of previously unknown subclinical hypothyroidism in obese patients referred to a sleep clinic for sleep disordered breathing.

    Science.gov (United States)

    Resta, O; Pannacciulli, N; Di Gioia, G; Stefàno, A; Barbaro, M P Foschino; De Pergola, G

    2004-10-01

    To evaluate the prevalence of previously unknown hypothyroidism in adult male and female patients with a wide range of body mass index (BMI) values, referred to a Sleep Clinic because of sleep disordered breathing (SDB). Serum concentrations of thyroid stimulating hormone (TSH) and free thyroxin (fT4), as well as forced vital capacity (FVC), PaO2, PaCO2, the Epworth sleepiness scale (ESS), respiratory disturbance index (RDI), loud snoring, and the percentage of total sleep time (TST) with obese adult subjects with no previous diagnosis of hypothyroidism (age: 18-72 years). The prevalence of previously undiagnosed subclinical hypothyroidism in the population as a whole was 11.5%. BMI, TSH and ESS were significantly higher in the hypothyroid than the euthyroid subjects, but there was no significant between-group difference in RDI, TST(saO2hypothyroid individuals, BMI, neck circumference, ESS, RDI and TST(Sao2hypothyroidism than that commonly reported in overweight and obese individuals referred to a Sleep Clinic for polysomnography because of SDB, thus suggesting that thyroid function should be evaluated in all obese patients suffering from SDB despite economic concerns.

  3. Rapid fish stock depletion in previously unexploited seamounts: the ...

    African Journals Online (AJOL)

    Rapid fish stock depletion in previously unexploited seamounts: the case of Beryx splendens from the Sierra Leone Rise (Gulf of Guinea). F Salmerón, J.C. Báez, D Macías, L Fernandez-Peralta, A Ramos ...

  4. Choice of contraception after previous operative delivery at a family ...

    African Journals Online (AJOL)

    Context: Effective contraceptive use is important after a caesarean or operative delivery because of the possible risks a woman may face in subsequent pregnancies. Objectives: The objective of the present study was to determine the uptake and choices of contraception among women with previous operative delivery.

  5. 2 CFR 225.45 - Relationship to previous issuance.

    Science.gov (United States)

    2010-01-01

    ... 2 Grants and Agreements 1 2010-01-01 2010-01-01 false Relationship to previous issuance. 225.45 Section 225.45 Grants and Agreements OFFICE OF MANAGEMENT AND BUDGET CIRCULARS AND GUIDANCE Reserved COST PRINCIPLES FOR STATE, LOCAL, AND INDIAN TRIBAL GOVERNMENTS (OMB CIRCULAR A-87) § 225.45 Relationship to...

  6. Recovery of Previously Uncultured Bacterial Genera from Three Mediterranean Sponges

    NARCIS (Netherlands)

    Versluis, Dennis; McPherson, Kyle; Passel, van Mark W.J.; Smidt, Hauke; Sipkema, Detmer

    2017-01-01

    Sponges often harbour a dense and diverse microbial community. Presently, a large discrepancy exists between the cultivable bacterial fraction from sponges and the community in its natural environment. Here, we aimed to acquire additional insights into cultivability of (previously uncultured)

  7. Snowfall in coastal West Antarctica much greater than previously assumed

    NARCIS (Netherlands)

    van den Broeke, M.R.|info:eu-repo/dai/nl/073765643; van de Berg, W.J.|info:eu-repo/dai/nl/304831611; van Meijgaard, E.

    2006-01-01

    A new Antarctic accumulation distribution, based on regional model output calibrated with 1900 in-situ observations, is used to re-assess accumulation in 24 Antarctic ice drainage basins. When compared to the previous compilation, good agreement is found for 19 of the 24 basins, representing 93% of

  8. 5 CFR 9701.352 - Use of highest previous rate.

    Science.gov (United States)

    2010-01-01

    ... HUMAN RESOURCES MANAGEMENT SYSTEM Pay and Pay Administration Pay Administration § 9701.352 Use of... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Use of highest previous rate. 9701.352 Section 9701.352 Administrative Personnel DEPARTMENT OF HOMELAND SECURITY HUMAN RESOURCES MANAGEMENT...

  9. Suburethral sling procedures after previous surgery for urinary ...

    African Journals Online (AJOL)

    Objective. To compare the outcome of suburethral sling procedures (tension-free vaginal tape (TVT), obturator tape (Ob-tape)) for stress urinary incontinence (SUI) in women with previous surgery for SUI or pelvic organ prolapse (POP). Methods. A comparative, descriptive, retrospective study was done using information ...

  10. 24 CFR 1710.552 - Previously accepted state filings.

    Science.gov (United States)

    2010-04-01

    ... HOUSING AND URBAN DEVELOPMENT (INTERSTATE LAND SALES REGISTRATION PROGRAM) LAND REGISTRATION Certification... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Previously accepted state filings. 1710.552 Section 1710.552 Housing and Urban Development Regulations Relating to Housing and Urban...

  11. Cryptococcal meningitis in a previously healthy child | Chimowa ...

    African Journals Online (AJOL)

    An 8-year-old previously healthy female presented with a 3 weeks history of headache, neck stiffness, deafness, fever and vomiting and was diagnosed with cryptococcal meningitis. She had documented hearing loss and was referred to tertiary-level care after treatment with fluconazole did not improve her neurological ...

  12. The impact of previous knowledge and experience on the ...

    African Journals Online (AJOL)

    The impact of previous knowledge and experience on the entrepreneurial attitudes of Grade 12 learners. ... The PDF file you selected should load here if your Web browser has a PDF reader plug-in installed (for example, a recent version of Adobe Acrobat Reader). If you would like more information about how to print, save, ...

  13. Abiraterone in metastatic prostate cancer without previous chemotherapy

    NARCIS (Netherlands)

    Ryan, C.J.; Smith, M.R.; Bono, J. De; Molina, A.; Logothetis, C.J.; Souza, P. de; Fizazi, K.; Mainwaring, P.; Piulats, J.M.; Ng, S.; Carles, J.; Mulders, P.F.A.; Basch, E.; Small, E.J.; Saad, F.; Schrijvers, D.; Poppel, H. van; Mukherjee, S.D.; Suttmann, H.; Gerritsen, W.R.; Flaig, T.W.; George, D.J.; Yu, E.Y.; Efstathiou, E.; Pantuck, A.; Winquist, E.; Higano, C.S.; Taplin, M.E.; Park, Y.; Kheoh, T.; Griffin, T.; Scher, H.I.; Rathkopf, D.E.

    2013-01-01

    BACKGROUND: Abiraterone acetate, an androgen biosynthesis inhibitor, improves overall survival in patients with metastatic castration-resistant prostate cancer after chemotherapy. We evaluated this agent in patients who had not received previous chemotherapy. METHODS: In this double-blind study, we

  14. Outcome Of Pregnancy Following A Previous Lower Segment ...

    African Journals Online (AJOL)

    Background: A previous ceasarean section is an important variable that influences patient management in subsequent pregnancies. A trial of vaginal delivery in such patients is a feasible alternative to a secondary section, thus aiding to reduce the ceasarean section rate and its associated co-morbidities. Objective: To ...

  15. A previously undescribed coronavirus associated with respiratory disease in humans.

    NARCIS (Netherlands)

    R.A.M. Fouchier (Ron); N.G. Hartwig (Nico); T.M. Bestebroer (Theo); B. Niemeyer (Berend); J.H. Simon (James); A.D.M.E. Osterhaus (Albert); J.C. de Jong (Jan)

    2004-01-01

    textabstractThe etiology of acute respiratory tract illnesses is sometimes unclear due to limitations of diagnostic tests or the existence of as-yet-unidentified pathogens. Here we describe the identification and characterization of a not previously recognized coronavirus obtained from an 8-mo-old

  16. 31 CFR 202.5 - Previously designated depositaries.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Previously designated depositaries. 202.5 Section 202.5 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE DEPOSITARIES AND FINANCIAL AGENTS...

  17. The job satisfaction of principals of previously disadvantaged schools

    African Journals Online (AJOL)

    The aim of this study was to identify influences on the job satisfaction of previously disadvantaged school principals in North-West Province. Evans's theory of job satis- faction, morale and motivation was useful as a conceptual framework. A mixed- methods explanatory research design was important in discovering issues ...

  18. The job satisfaction of principals of previously disadvantaged schools

    African Journals Online (AJOL)

    The aim of this study was to identify influences on the job satisfaction of previously disadvantaged school principals in North-West Province. Evans's theory of job satisfaction, morale and motivation was useful as a conceptual framework. A mixedmethods explanatory research design was important in discovering issues with ...

  19. Report

    Directory of Open Access Journals (Sweden)

    Akin Aydogan

    2012-01-01

    Full Text Available Introduction. Gossypiboma (GP is a term used to express the mass resulting from forgotten cotton sponge in operations. Rarely, a transmural migration may occur into the gastrointestinal lumen without creating any defect by GP. Laparotomy or endoscopic removal may be required, by the way it can be taken out of the body itself by intestinal ways. In this study, we reported a case of mechanical intestinal obstruction causing GP. Case. The fifty-one-year-old female patient admitted to the emergency department with the complaints of mechanical intestinal obstruction and had a history of open cholecystectomy 20 years ago. There were the findings of intestinal obstruction in abdominal plain radiography and computerized tomography. The sponge that obstructed the lumen completely 40 cm proximal to the ileocecal valve was identified in the laparotomy with the diagnosis of brid ileus. The small intestine was closed over double-fold after removal of sponge. Transmural migration of abdominal-remained sponge was thought to be occurred without creating a defect after cholecystectomy. Postoperatively, the patient was discharged without having any problems at 4th day of hospitalization. Conclusion. Although it is a rare situation in routine clinical practice, GP should be considered as a differential diagnosis in the patients who had a diagnosis of mechanical intestinal obstruction, and laparotomy was applied before. As GP may lead to situations which cause mortality, all precautions should be taken to prevent it.

  20. The pathogenicity of genetic variants previously associated with left ventricular non-compaction

    DEFF Research Database (Denmark)

    Abbasi, Yeganeh; Jabbari, Javad; Jabbari, Reza

    2016-01-01

    an updated list of previously reported LVNC-associated variants with biologic description and investigate the prevalence of LVNC variants in healthy general population to find false-positive LVNC-associated variants. METHODS AND RESULTS: The Human Gene Mutation Database and PubMed were systematically...... searched to identify all previously reported LVNC-associated variants. Thereafter, the Exome Sequencing Project (ESP) and the Exome Aggregation Consortium (ExAC), that both represent the background population, was searched for all variants. Four in silico prediction tools were assessed to determine...

  1. Lightning detection and ranging

    Science.gov (United States)

    Lennon, C. L.; Poehler, H. A.

    1982-01-01

    A lightning detector and ranging (LDAR) system developed at the Kennedy Space Center and recently transferred to Wallops Island is described. The system detects pulsed VHF signals due to electrical discharges occurring in a thunderstorm by means of 56-75 MHz receivers located at the hub and at the tips of 8 km radial lines. Incoming signals are transmitted by wideband links to a central computing facility which processes the times of arrival, using two independent calculations to determine position in order to guard against false data. The results are plotted on a CRT display, and an example of a thunderstorm lightning strike detection near Kennedy Space Center is outlined. The LDAR correctly identified potential ground strike zones and additionally provided a high correlation between updrafts and ground strikes.

  2. Range ecosystem management for natural areas

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report describes methods for managing range ecosystems in natural areas. Preserved natural areas on rangeland may, in a short time, be only those which received...

  3. A theoretical explanation for previously infertile mothers' vulnerability to depression.

    Science.gov (United States)

    Olshansky, Ellen

    2003-01-01

    To present a theoretical approach to understanding the potential vulnerability to depression in previously infertile new mothers. This approach was developed by synthesizing results of a series of grounded theory studies of experiences of infertility and pregnancy and of parenting after infertility. These results were further synthesized with the relational cultural theory (RCT). Previously infertile new mothers have experienced repeated and sustained interferences with significant relationships over the course of their infertility, which could lead to depression. Implications of this theoretical perspective include: (a) it is a new approach to understanding a significant and sometimes minimized issue in women's health; (b) it is a basis for designing an intervention for women coping with infertility and its aftermath; and (c) it might be applied to other women's health issues.

  4. Robotic Assisted Laparoscopic Prostatectomy Performed after Previous Suprapubic Prostatectomy.

    Science.gov (United States)

    Tsui, Johnson F; Feuerstein, Michael; Jazayeri, Seyed Behzad; Samadi, David B

    2016-01-01

    Operative management of prostate cancer in a patient who has undergone previous open suprapubic simple prostatectomy poses a unique surgical challenge. Herein, we describe a case of intermediate risk prostate cancer in a man who had undergone simple prostatectomy ten years prior to presentation. The patient was found to have Gleason 7 prostate cancer on MRI fusion biopsy of the prostate for elevated PSA and underwent an uncomplicated robot assisted laparoscopic radical prostatectomy.

  5. Robotic Assisted Laparoscopic Prostatectomy Performed after Previous Suprapubic Prostatectomy

    Directory of Open Access Journals (Sweden)

    Johnson F. Tsui

    2016-01-01

    Full Text Available Operative management of prostate cancer in a patient who has undergone previous open suprapubic simple prostatectomy poses a unique surgical challenge. Herein, we describe a case of intermediate risk prostate cancer in a man who had undergone simple prostatectomy ten years prior to presentation. The patient was found to have Gleason 7 prostate cancer on MRI fusion biopsy of the prostate for elevated PSA and underwent an uncomplicated robot assisted laparoscopic radical prostatectomy.

  6. A previously unidentified host protein protects retroviral DNA from autointegration

    OpenAIRE

    Lee, Myung Soo; Craigie, Robert

    1998-01-01

    Integration of a DNA copy of the viral genome into a host chromosome is an essential step in the retrovirus life cycle. The machinery that carries out the integration reaction is a nucleoprotein complex derived from the core of the infecting virion. To successfully integrate into host DNA, the viral DNA within this complex must avoid self-destructive integration into itself, a reaction termed autointegration. We have previously shown [Lee, M. S. and Craigie, R. (1994) Proc. Natl. Acad. Sci. U...

  7. An algorithm for segmenting range imagery

    Energy Technology Data Exchange (ETDEWEB)

    Roberts, R.S.

    1997-03-01

    This report describes the technical accomplishments of the FY96 Cross Cutting and Advanced Technology (CC&AT) project at Los Alamos National Laboratory. The project focused on developing algorithms for segmenting range images. The image segmentation algorithm developed during the project is described here. In addition to segmenting range images, the algorithm can fuse multiple range images thereby providing true 3D scene models. The algorithm has been incorporated into the Rapid World Modelling System at Sandia National Laboratory.

  8. The encoding complexity of two dimensional range minimum data structures

    DEFF Research Database (Denmark)

    Brodal, Gerth Stølting; Brodnik, Andrej; Davoodi, Pooya

    2013-01-01

    of the encoding variant of the problem where queries have access to the constructed data structure but can not access the input matrix A, i.e. all information must be encoded in the data structure. Previously it was known how to solve the problem with space O(mn min {m,logn}) bits (and with constant query time......In the two-dimensional range minimum query problem an input matrix A of dimension m ×n, m ≤ n, has to be preprocessed into a data structure such that given a query rectangle within the matrix, the position of a minimum element within the query range can be reported. We consider the space complexity...

  9. New data structures for orthogonal range searching

    DEFF Research Database (Denmark)

    Alstrup, Stephen; Brodal, Gerth Stølting; Rauhe, Theis

    2000-01-01

    We present new general techniques for static orthogonal range searching problems in two and higher dimensions. For the general range reporting problem in R3, we achieve query time O(log n+k) using space O(n log1+ε n), where n denotes the number of stored points and k the number of points to be re...

  10. Previous Violent Events and Mental Health Outcomes in Guatemala

    Science.gov (United States)

    Puac-Polanco, Victor D.; Lopez-Soto, Victor A.; Kohn, Robert; Xie, Dawei; Richmond, Therese S.

    2015-01-01

    Objectives. We analyzed a probability sample of Guatemalans to determine if a relationship exists between previous violent events and development of mental health outcomes in various sociodemographic groups, as well as during and after the Guatemalan Civil War. Methods. We used regression modeling, an interaction test, and complex survey design adjustments to estimate prevalences and test potential relationships between previous violent events and mental health. Results. Many (20.6%) participants experienced at least 1 previous serious violent event. Witnessing someone severely injured or killed was the most common event. Depression was experienced by 4.2% of participants, with 6.5% experiencing anxiety, 6.4% an alcohol-related disorder, and 1.9% posttraumatic stress disorder (PTSD). Persons who experienced violence during the war had 4.3 times the adjusted odds of alcohol-related disorders (P < .05) and 4.0 times the adjusted odds of PTSD (P < .05) compared with the postwar period. Women, indigenous Maya, and urban dwellers had greater odds of experiencing postviolence mental health outcomes. Conclusions. Violence that began during the civil war and continues today has had a significant effect on the mental health of Guatemalans. However, mental health outcomes resulting from violent events decreased in the postwar period, suggesting a nation in recovery. PMID:25713973

  11. Evaluation of cleansing methods for previously worn prostheses.

    Science.gov (United States)

    Glass, R Thomas; Conrad, Robert S; Bullard, James W; Goodson, Leigh B; Mehta, Naresh; Lech, Stanley J; Loewy, Zvi G

    2011-04-01

    Although there are many product claims that address the issue of denture sanitization, controlled scientific studies on previously worn dentures have not been performed. The purpose of this study was to evaluate procedures directed at sanitizing previously worn contaminated dentures from two regions of the United States. This study examined 51 previously worn dentures from two regions. An established method of denture retrieval, sectioning, and culturing was used, including isolation of anaerobes. Evaluation of microbial contamination posttreatment was used to determine the effects of soaking dentures in Polident (US and European formulations) for varying periods of times/temperatures, microwaving dentures with varying temperatures, sonicating dentures, and immersing the dentures while using a vacuum. A combination of analysis of variance (ANOVA) and general linear model (GLM) of the SPSS was used to analyze the data with P sanitization rather than sterilization. Denture-borne microorganisms can be significantly reduced by using a Polident solution for 8 hours at room temperature or for 5 minutes at 65 degrees C. Microwaving, sonication, and use of a vacuum were less effective. ClLINICAL IMPLICATIONS The importance of daily use of Polident solution for 8 hours or for 5 minutes at 65 degrees C to sanitize worn prostheses must be stressed.

  12. Subsequent pregnancy outcomes in women previously diagnosed with subclinical hypothyroidism.

    Science.gov (United States)

    Nelson, David B; Casey, Brian M; McIntire, Donald D; Cunningham, F Gary

    2014-01-01

    To evaluate subsequent pregnancy outcomes in women previously identified during an index pregnancy to have subclinical hypothyroidism (SCH). From 2000 to 2003, thyroid analytes were measured in 17,298 women. Using their index pregnancy thyroid-analyte classification, pregnancy outcomes were compared between the returning cohorts. There were 6,985 women previously screened and subsequently delivered at our hospital though 2011 with 230 (3.3%) designated to have SCH and 6,645 (95.1%) euthyroid. Significant differences between the two cohorts included risk for diabetes (odds ratio [OR] 1.8, 95% confidence interval [CI] 1.2 to 2.7, p = 0.005), gestational diabetes (OR 1.74, 95% CI 1.13 to 2.69, p = 0.015), and stillbirth (OR 3.5, 95% CI 1.05 to 11.68, p = 0.042). After adjustment, the increased likelihood of diabetes (adjusted OR 1.58, 95% CI 1.04 to 2.40, p = 0.032) and stillbirth (adjusted OR 3.41, 95% CI 1.01 to 11.49, p = 0.048) persisted. Women identified during a previous pregnancy with SCH are at increased risk for some adverse perinatal outcomes during a subsequent pregnancy. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  13. African Journal of Range and Forage Science

    African Journals Online (AJOL)

    The African Journal of Range & Forage Science (previously known as Proceedings of the Grassland Society of Southern Africa and Journal of the Grassland Society of Southern Africa) is the leading rangeland and pastoral journal in Africa, and serves as an important reference for anyone interested in the management and ...

  14. Previous toothache, dental visits and caries presence among ...

    African Journals Online (AJOL)

    Background: Dental pain is an ache or soreness within or around a tooth. It has a wide range of etiology, the commonest being dental caries. Dental pain is one of the main reasons for seeking dental care. Objectives: To assess the relationship between experiences of toothache, dental visits and caries experience among ...

  15. Extra-Gastrointestinal Manifestations of Inflammatory Bowel Disease May Be Less Common Than Previously Reported.

    Science.gov (United States)

    Card, Timothy R; Langan, Sinéad M; Chu, Thomas P C

    2016-09-01

    Extra-intestinal manifestations are well recognized in inflammatory bowel disease (IBD). To what extent the commonly recognized extra-intestinal manifestations seen in IBD patients are attributable to IBD is, however, not clear due to the limited number of controlled studies published. We have conducted a study of these manifestations using electronic primary care records. We have identified extra-intestinal manifestations in IBD and non-IBD patients and derived odds ratios (ORs) using conditional logistic regression. A total of 56,097 IBD patients (32.5 % Crohn's disease, 48.3 % ulcerative colitis (UC) and 19.2 % not classified) were matched to 280,382 non-IBD controls. We found records of pyoderma gangrenosum (OR = 29.24), erythema nodosum (OR = 5.95), primary sclerosing cholangitis (OR = 188.25), uveitis (OR = 2.81), ankylosing spondylitis (OR = 7.07), sacroiliitis (OR = 2.79) and non-rheumatoid inflammatory arthritides (OR = 2.66) to be associated with IBD. One or more of these was recorded in 8.1 % of IBD patients and 2.3 % of controls. Non-specific arthritides were present in many more patients, affecting 30 % of IBD patients and 23.8 % of controls overall. We also found weaker associations with a number of conditions not generally considered to be extra-intestinal manifestations including psoriasis, ischemic heart disease, multiple sclerosis and hay fever. Although "classical" extra-intestinal manifestations are strongly associated with IBD, most IBD patients remain unaffected. Arthropathies, perceived to be the commonest extra-intestinal manifestation, are not strongly associated with IBD, and the proportion of arthropathies attributable to IBD is likely to be small.

  16. Extra-Gastrointestinal Manifestations of Inflammatory Bowel Disease May Be Less Common Than Previously Reported.

    OpenAIRE

    Card, TR; Langan, SM; Chu, TP

    2016-01-01

    Extra-intestinal manifestations are well recognized in inflammatory bowel disease (IBD). To what extent the commonly recognized extra-intestinal manifestations seen in IBD patients are attributable to IBD is, however, not clear due to the limited number of controlled studies published. We have conducted a study of these manifestations using electronic primary care records. We have identified extra-intestinal manifestations in IBD and non-IBD patients and derived odds ratios (ORs) using condit...

  17. Vapor pressures of substituted polycarboxylic acids are much lower than previously reported

    Directory of Open Access Journals (Sweden)

    A. J. Huisman

    2013-07-01

    Full Text Available The partitioning of compounds between the aerosol and gas phase is a primary focus in the study of the formation and fate of secondary organic aerosol. We present measurements of the vapor pressure of 2-methylmalonic (isosuccinic acid, 2-hydroxymalonic (tartronic acid, 2-methylglutaric acid, 3-hydroxy-3-carboxy-glutaric (citric acid and DL-2,3-dihydroxysuccinic (DL-tartaric acid, which were obtained from the evaporation rate of supersaturated liquid particles levitated in an electrodynamic balance. Our measurements indicate that the pure component liquid vapor pressures at 298.15 K for tartronic, citric and tartaric acids are much lower than the same quantity that was derived from solid state measurements in the only other room temperature measurement of these materials (made by Booth et al., 2010. This strongly suggests that empirical correction terms in a recent vapor pressure estimation model to account for the inexplicably high vapor pressures of these and similar compounds should be revisited, and that due caution should be used when the estimated vapor pressures of these and similar compounds are used as inputs for other studies.

  18. Pulmonary carcinosarcoma initially presenting as invasive aspergillosis: a case report of previously unreported combination

    Directory of Open Access Journals (Sweden)

    Van Thien

    2010-01-01

    Full Text Available Abstract Carcinosarcoma of the lung is a malignant tumor composed of a mixture of carcinoma and sarcoma elements. The carcinomatous component is most commonly squamous followed by adenocarcinoma. The sarcomatous component commonly comprises the bulk of the tumor and shows poorly differentiated spindle cell features. Foci of differentiated sarcomatous elements such as chondrosarcoma and osteosarcoma may be seen. Aspergillus pneumonia is the most common form of invasive aspergillosis and occurs mainly in patients with malignancy, immunocompromizing or debilitating diseases. Patients with Aspergillus pneumonia present with fever, cough, chest pain and occasionally hemoptysis. Tissue examination is the most reliable method for diagnosis, and mortality rate is high. We describe a case of primary carcinosarcoma of the lung concurrently occurring with invasive pulmonary aspergillosis in a 66-year old patient.

  19. Non-detection of Previously Reported Transits of HD 97658b with MOST Photometry

    DEFF Research Database (Denmark)

    Dragomir, Diana; Matthews, Jaymie M.; Howard, Andrew W.

    2012-01-01

    The radial velocity-discovered exoplanet HD 97658b was recently announced to transit, with a derived planetary radius of 2.93 ± 0.28 R ⊕. As a transiting super-Earth orbiting a bright star, this planet would make an attractive candidate for additional observations, including studies of its atmosp...

  20. Internal carotid occlusion in a patient with previous history of periodontitis: case report.

    Science.gov (United States)

    Puhar, Ivan; Lovrencić-Huzjan, Arijana; Plancak, Darije; Sodec-Simicević, Darja; Strineka, Maja; Demarin, Vida

    2012-09-01

    Although inflammatory periodontal disease has been proven to be related to carotid intima media thickness, it has been recently suggested that even an alteration of carotid hemodynamics might contribute to atherosclerosis in patients with periodontal disease. A 52-year-old female patient was referred to periodontology department due to painful alveolar mucosa. On the basis of dental history, we concluded that the patient had a severe form of generalized aggressive periodontitis that led to complete edentulism. The patient was advised to undergo ultrasonography of carotid arteries with arterial stiffness measurements at neurology department. A diagnosis of the right internal carotid artery occlusion was established. Inflammatory periodontal disease may affect arterial hemodynamics and even lead to artery occlusion. It is advisable that patients with a severe form of periodontitis should be referred for carotid artery ultrasonography.

  1. Previously undiagnosed hereditary spherocytosis in a patient with jaundice and pyelonephritis: a case report.

    Science.gov (United States)

    Tateno, Yuki; Suzuki, Ryoji; Kitamura, Yukihiro

    2016-12-01

    Hereditary spherocytosis is autosomal dominant inherited extravascular hemolytic disorder and is the commonest cause of inherited hemolysis in northern Europe and the United States. The classical clinical features of hereditary spherocytosis are anemia, jaundice, and splenomegaly. However, all of these classical features are not always revealed in the case of mild hemolysis or when hemolysis is well compensated. Patients with hereditary spherocytosis may remain undiagnosed for years if their hemolysis is mild. A 42-year-old Asian woman presented to our clinic with a sudden onset of high fever with shaking chills and jaundice, suggesting septicemia; however, following detailed investigation, the patient was diagnosed with pyelonephritis and accelerated hemolysis of hereditary spherocytosis due to infection. It is important to note that transient anemia or jaundice can sometimes be the only initial presenting symptoms in cases of undiagnosed latent hereditary spherocytosis. This case also highlights the fact that physicians should consider concomitant hemolytic disease in patients in whom jaundice and infections that rarely cause jaundice coexist.

  2. Amount of polyhydramnios attributable to diabetes may be less than previously reported.

    Science.gov (United States)

    Moore, Lisa E

    2017-01-15

    To evaluate the frequency and the quantity of polyhydramnios attributable to diabetes in pregnancy. The charts of patients with a four-quadrant amniotic fluid index (AFI) ≥ 20 cm and either a diagnosis of diabetes or a diabetes screening test during the index pregnancy were retrospectively reviewed. AFI was stratified into 5 categories and the frequency of diabetes was evaluated for each group. The frequency of polyhydramnios attributable to diabetes was compared to the frequency of polyhydramnios in the setting of fetal anomalies or no known cause. One thousand five hundred and forty-five patients were included in the study. Eight point five percent ( n = 131) had diabetes and no other cause for polyhydramnios. Eleven point two percent (173) had antenatally diagnosed anomalies. For all categories of AFI except the largest (> 40.9 cm) the most common cause of polyhydramnios was idiopathic. In patients with diabetes the AFI was most likely to be between 26 cm and 35.9 cm. The rate of polyhydramnios in this study is 8.5%. Patients with diabetes most commonly have mild polyhydramnios between 26 and 35.9 cm of fluid on a four-quadrant AFI.

  3. Amount of polyhydramnios attributable to diabetes may be less than previously reported

    OpenAIRE

    Moore, Lisa E

    2017-01-01

    AIM To evaluate the frequency and the quantity of polyhydramnios attributable to diabetes in pregnancy. METHODS The charts of patients with a four-quadrant amniotic fluid index (AFI) ? 20 cm and either a diagnosis of diabetes or a diabetes screening test during the index pregnancy were retrospectively reviewed. AFI was stratified into 5 categories and the frequency of diabetes was evaluated for each group. The frequency of polyhydramnios attributable to diabetes was compared to the frequency ...

  4. Malignant Triton Tumor of the Kidney. New Location Not Previously Reported.

    Science.gov (United States)

    Gallego, Angel; Pontones, Jose Luis; Ramos, David; Boronat, Francisco

    2017-01-01

    Malignant triton tumor (MTT) is a variant of the peripheral nerve sheath tumor. It is very uncommon but shows an aggressive course and limited survival. Half of the cases present symptoms related to neurofibromatosis type 1 disease. There is no standardized treatment, but multimodal approach is the best option. We present the case of a primary MTT located in the kidney, in a 43-year-old woman who received neoadjuvant chemotherapy as first-line treatment followed by surgical resection and adjuvant chemotherapy. © 2015 S. Karger AG, Basel.

  5. A case of squamous cell carcinoma caused by previous irradiation to the giant pigmented nevus

    Energy Technology Data Exchange (ETDEWEB)

    Hoashi, Toshihiko; Kakinuma, Takashi; Idetsuki, Takeo; Kawabata, Yasuhiro; Imakado, Sumihisa; Tamaki, Kunihiko [Tokyo Univ. (Japan). Faculty of Medicine

    1999-02-01

    We report a case of squamous cell carcinoma of the left leg caused by previous irradiation to the giant pigmented nevus. In treating skin cancers originated from radiation dermatitis, we think it is important to resect surrounding radiation dermatitis lesions as well as tumor itself. (author)

  6. Possible pulmonary Rhizopus oryzae infection in a previously healthy child after a near-drowning incident.

    Science.gov (United States)

    Gerlach, Magdalena M; Lippmann, Norman; Kobelt, Louise; Petzold-Quinque, Stefanie; Ritter, Lutz; Kiess, Wieland; Siekmeyer, Manuela

    2016-06-01

    This article reports on a previously healthy 17-month-old boy who developed pulmonary mucormycosis after a near-drowning incident in a goose pond. The patient survived without neurological sequelae and recovered, under treatment with amphotericin B, from the rare and often invasive fungal infection with Rhizopus spp., usually occurring in immunodeficient patients.

  7. Incidence of cancer in adolescent idiopathic scoliosis patients treated 25 years previously

    DEFF Research Database (Denmark)

    Simony, Ane; Hansen, Emil Jesper; Christensen, Steen Bach

    2016-01-01

    PURPOSE: To report the incidence of cancer in a cohort of adolescent idiopathic scoliosis (AIS) patients treated 25 years previously. METHODS: 215 consecutive AIS patients treated between 1983 and 1990 were identified and requested to return for clinical and radiographic examination. The incidence...

  8. Do previous experience and geographic proximity matter? Possible predictors for diagnosing Adjustment disorder vs. PTSD.

    Science.gov (United States)

    Mahat-Shamir, Michal; Ring, Lia; Hamama-Raz, Yaira; Ben-Ezra, Menachem; Pitcho-Prelorentzos, Shani; David, Udi Y; Zaken, Adi; Lavenda, Osnat

    2017-12-01

    The minority of people who have experienced a traumatic event and were diagnosed as either suffering from PTSD or from Adjustment disorder, may suggest that victims of a traumatic event vary in risk factors for the disorders. The current research aimed at examining the association between reports of Adjustment disorder and PTSD symptoms (In accordance with the proposed revisions of the ICD-11) and several vulnerability variables: previous traumatic event, previous stressful event and physical proximity to the terror attack. Using an online survey, 379 adult participants were recruited, and filled out Adjustment disorder, PTSD symptomatology scales, as well as a previous exposure, magnitude of exposure and death anxiety scales. Findings revealed that previous experience of traumatic events was a significant predictor associated with both PTSD and Adjustment disorder symptoms. Previous experience of stressful events was a significant predictor associated with Adjustment disorder alone. Physical proximity to the site of the attack was a significant predictor associated with PTSD symptoms but not Adjustment disorder symptoms. The importance of previous traumatic events, previous stressful events and physical proximity to the terror attack as factors which are associated with Adjustment disorder and PTSD symptomatology is discussed. Copyright © 2017 Elsevier B.V. All rights reserved.

  9. Women with previous stress fractures show reduced bone material strength.

    Science.gov (United States)

    Duarte Sosa, Daysi; Fink Eriksen, Erik

    2016-12-01

    Background and purpose - Bone fragility is determined by bone mass, bone architecture, and the material properties of bone. Microindentation has been introduced as a measurement method that reflects bone material properties. The pathogenesis of underlying stress fractures, in particular the role of impaired bone material properties, is still poorly understood. Based on the hypothesis that impaired bone material strength might play a role in the development of stress fractures, we used microindentation in patients with stress fractures and in controls. Patients and methods - We measured bone material strength index (BMSi) by microindentation in 30 women with previous stress fractures and in 30 normal controls. Bone mineral density by DXA and levels of the bone markers C-terminal cross-linking telopeptide of type-1 collagen (CTX) and N-terminal propeptide of type-1 procollagen (P1NP) were also determined. Results - Mean BMSi in stress fracture patients was significantly lower than in the controls (SD 72 (8.7) vs. 77 (7.2); p = 0.02). The fracture subjects also had a significantly lower mean bone mineral density (BMD) than the controls (0.9 (0.02) vs. 1.0 (0.06); p = 0.03). Bone turnover-as reflected in serum levels of the bone marker CTX-was similar in both groups, while P1NP levels were significantly higher in the women with stress fractures (55 μg/L vs. 42 μg/L; p = 0.03). There was no correlation between BMSi and BMD or bone turnover. Interpretation - BMSi was inferior in patients with previous stress fracture, but was unrelated to BMD and bone turnover. The lower values of BMSi in patients with previous stress fracture combined with a lower BMD may contribute to the increased propensity to develop stress fractures in these patients.

  10. Sofosbuvir, Velpatasvir, and Voxilaprevir for Previously Treated HCV Infection.

    Science.gov (United States)

    Bourlière, Marc; Gordon, Stuart C; Flamm, Steven L; Cooper, Curtis L; Ramji, Alnoor; Tong, Myron; Ravendhran, Natarajan; Vierling, John M; Tran, Tram T; Pianko, Stephen; Bansal, Meena B; de Lédinghen, Victor; Hyland, Robert H; Stamm, Luisa M; Dvory-Sobol, Hadas; Svarovskaia, Evguenia; Zhang, Jie; Huang, K C; Subramanian, G Mani; Brainard, Diana M; McHutchison, John G; Verna, Elizabeth C; Buggisch, Peter; Landis, Charles S; Younes, Ziad H; Curry, Michael P; Strasser, Simone I; Schiff, Eugene R; Reddy, K Rajender; Manns, Michael P; Kowdley, Kris V; Zeuzem, Stefan

    2017-06-01

    Patients who are chronically infected with hepatitis C virus (HCV) and who do not have a sustained virologic response after treatment with regimens containing direct-acting antiviral agents (DAAs) have limited retreatment options. We conducted two phase 3 trials involving patients who had been previously treated with a DAA-containing regimen. In POLARIS-1, patients with HCV genotype 1 infection who had previously received a regimen containing an NS5A inhibitor were randomly assigned in a 1:1 ratio to receive either the nucleotide polymerase inhibitor sofosbuvir, the NS5A inhibitor velpatasvir, and the protease inhibitor voxilaprevir (150 patients) or matching placebo (150 patients) once daily for 12 weeks. Patients who were infected with HCV of other genotypes (114 patients) were enrolled in the sofosbuvir-velpatasvir-voxilaprevir group. In POLARIS-4, patients with HCV genotype 1, 2, or 3 infection who had previously received a DAA regimen but not an NS5A inhibitor were randomly assigned in a 1:1 ratio to receive sofosbuvir-velpatasvir-voxilaprevir (163 patients) or sofosbuvir-velpatasvir (151 patients) for 12 weeks. An additional 19 patients with HCV genotype 4 infection were enrolled in the sofosbuvir-velpatasvir-voxilaprevir group. In the three active-treatment groups, 46% of the patients had compensated cirrhosis. In POLARIS-1, the rate of sustained virologic response was 96% with sofosbuvir-velpatasvir-voxilaprevir, as compared with 0% with placebo. In POLARIS-4, the rate of response was 98% with sofosbuvir-velpatasvir-voxilaprevir and 90% with sofosbuvir-velpatasvir. The most common adverse events were headache, fatigue, diarrhea, and nausea. In the active-treatment groups in both trials, the percentage of patients who discontinued treatment owing to adverse events was 1% or lower. Sofosbuvir-velpatasvir-voxilaprevir taken for 12 weeks provided high rates of sustained virologic response among patients across HCV genotypes in whom treatment with a DAA regimen

  11. Moyamoya disease in a child with previous acute necrotizing encephalopathy

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Taik-Kun; Cha, Sang Hoon; Chung, Kyoo Byung; Kim, Jung Hyuck; Kim, Baek Hyun; Chung, Hwan Hoon [Department of Diagnostic Radiology, Korea University College of Medicine, Ansan Hospital, 516 Kojan-Dong, Ansan City, Kyungki-Do 425-020 (Korea); Eun, Baik-Lin [Department of Pediatrics, Korea University College of Medicine, Seoul (Korea)

    2003-09-01

    A previously healthy 24-day-old boy presented with a 2-day history of fever and had a convulsion on the day of admission. MRI showed abnormal signal in the thalami, caudate nuclei and central white matter. Acute necrotising encephalopathy was diagnosed, other causes having been excluded after biochemical and haematological analysis of blood, urine and CSF. He recovered, but with spastic quadriparesis. At the age of 28 months, he suffered sudden deterioration of consciousness and motor weakness of his right limbs. MRI was consistent with an acute cerebrovascular accident. Angiography showed bilateral middle cerebral artery stenosis or frank occlusion with numerous lenticulostriate collateral vessels consistent with moyamoya disease. (orig.)

  12. Fulminant Pneumococcal Pericarditis in a Previously Healthy Patient.

    Science.gov (United States)

    Trpkov, Cvetan; Nath, Ermin; Moon, Michael; Windram, Jonathan; Graham, Michelle M

    2017-04-01

    Purulent pericarditis is a rare acutely life-threatening condition. Initial symptoms, signs, and investigations can be nonspecific. Echocardiography is invaluable for establishing the diagnosis and initial management. We present a case of a previously healthy patient with purulent pericarditis caused by Streptococcus pneumoniae in the absence of a primary focus of infection. The patient deteriorated rapidly with cardiac tamponade and septic shock and was managed successfully by a combined medical and surgical approach. Copyright © 2016 Canadian Cardiovascular Society. Published by Elsevier Inc. All rights reserved.

  13. Kidnapping Detection and Recognition in Previous Unknown Environment

    Directory of Open Access Journals (Sweden)

    Yang Tian

    2017-01-01

    Full Text Available An unaware event referred to as kidnapping makes the estimation result of localization incorrect. In a previous unknown environment, incorrect localization result causes incorrect mapping result in Simultaneous Localization and Mapping (SLAM by kidnapping. In this situation, the explored area and unexplored area are divided to make the kidnapping recovery difficult. To provide sufficient information on kidnapping, a framework to judge whether kidnapping has occurred and to identify the type of kidnapping with filter-based SLAM is proposed. The framework is called double kidnapping detection and recognition (DKDR by performing two checks before and after the “update” process with different metrics in real time. To explain one of the principles of DKDR, we describe a property of filter-based SLAM that corrects the mapping result of the environment using the current observations after the “update” process. Two classical filter-based SLAM algorithms, Extend Kalman Filter (EKF SLAM and Particle Filter (PF SLAM, are modified to show that DKDR can be simply and widely applied in existing filter-based SLAM algorithms. Furthermore, a technique to determine the adapted thresholds of metrics in real time without previous data is presented. Both simulated and experimental results demonstrate the validity and accuracy of the proposed method.

  14. Are previous suicide attempts a risk factor for completed suicide?

    Science.gov (United States)

    Goñi-Sarriés, Adriana; Blanco, Miriam; Azcárate, Leire; Peinado, Rubén; López-Goñi, José J

    2018-02-01

    A previous suicide attempt is a clinically relevant factor for completed suicide. In this paper people who committed suicide on their first attempt are compared with those who did so after previous attempts. A review of the Computerised Clinical Histories in the Navarro Health Service-Osasunbidea (2010-2013) in Spain. Of the 166 cases, 31.9% (n = 53) presented at least one prior attempt. Of these 53, 65.3% modified the method of suicide. Women presented significantly more attempts (χ2 = 14.3; df = 3; p = .002). Three sub-samples were identified according to the attempts and diagnoses. The diagnoses of personality disorders (90.9%; n = 10) and women under 51 years of age with a diagnosis of affective, anxiety, or substance abuse disorders (82.4%; n = 14) presented the highest numbers of attempts. People without a psychiatric diagnosis and with psychotic or organic mental disorders presented the smallest proportion of attempts (13.2%; n = 10) together with people over 51 years of age diagnosed with affective, anxiety, or substance abuse disorders (22.5%; n = 9). Prior attempts are suicide risk factors only in specific clinical sub-samples. Prevention and intervention programs should consider these results.

  15. Incidence of Acneform Lesions in Previously Chemically Damaged Persons-2004

    Directory of Open Access Journals (Sweden)

    N Dabiri

    2008-04-01

    Full Text Available ABSTRACT: Introduction & Objective: Chemical gas weapons especially nitrogen mustard which was used in Iraq-Iran war against Iranian troops have several harmful effects on skin. Some other chemical agents also can cause acne form lesions on skin. The purpose of this study was to compare the incidence of acneform in previously chemically damaged soldiers and non chemically damaged persons. Materials & Methods: In this descriptive and analytical study, 180 chemically damaged soldiers, who have been referred to dermatology clinic between 2000 – 2004, and forty non-chemically damaged people, were chosen randomly and examined for acneform lesions. SPSS software was used for statistic analysis of the data. Results: The mean age of the experimental group was 37.5 ± 5.2 and that of the control group was 38.7 ± 5.9 years. The mean percentage of chemical damage in cases was 31 percent and the time after the chemical damage was 15.2 ± 1.1 years. Ninety seven cases (53.9 percent of the subjects and 19 people (47.5 percent of the control group had some degree of acne. No significant correlation was found in incidence, degree of lesions, site of lesions and age of subjects between two groups. No significant correlation was noted between percentage of chemical damage and incidence and degree of lesions in case group. Conclusion: Incidence of acneform lesions among previously chemically injured peoples was not higher than the normal cases.

  16. Paternity after vasectomy with two previous semen analyses without spermatozoa

    OpenAIRE

    Lucon, Marcos; Lucon, Antonio Marmo; Pasqualoto, Fabio Firmbach; Srougi, Miguel

    2007-01-01

    CONTEXT: The risk of paternity after vasectomy is rare but still exists. Overall failure to achieve sterility after vasectomy occurs in 0.2 to 5.3% of patients due to technical failure or recanalization. The objective of this report was to describe a rare but notable case of proven paternity in which the semen analyses had not given evidence of spermatozoa. CASE REPORT: A 44-year-old vasectomized man whose semen analyses had shown azoospermia became a father four years after sterilization. Bl...

  17. Revised tephra volumes for Cascade Range volcanoes

    Science.gov (United States)

    Nathenson, Manuel

    2017-01-01

    Isopach maps from tephra eruptions from Mount St. Helens were reported in Carey et al. (1995) and for tephra eruptions from Glacier Peak in Gardner et al. (1998). For exponential thinning, the isopach data only define a single slope on a log thickness versus square root of area plot. Carey et al. (1995) proposed a model that was used to estimate a second slope, and volumes were presented in both studies using this model. A study by Sulpizio (2005) for estimating the second slope and square root of area where the lines intersect involves a systematic analysis of many eruptions to provide correlation equations. The purpose of this paper is to recalculate the volumes of Cascades eruptions and compare results from the two methods. In order to gain some perspective on the methods for estimating the second slope, we use data for thickness versus distance beyond the last isopach that are available for some of the larger eruptions in the Cascades. The thickness versus square root of area method is extended to thickness versus distance by developing an approximate relation between the two assuming elliptical isopachs with the source at one of the foci. Based on the comparisons made between the Carey et al. (1995) and Sulpizio (2005) methods, it is felt that the later method provides a better estimate of the second slope. For Mount St. Helens, the estimates of total volume using the Sulpizio (2005) method are generally smaller than those using the Carey et al. (1995) method. For the volume estimates of Carey et al. (1995), the volume of the May 18, 1980, eruption of Mount St. Helens is smaller than six of the eight previous eruptions. With the new volumes using the Sulpizio (2005) method, the 1980 eruption is smaller in volume than the upper end of the range for only three of the layers (Wn, Ye, and Yn) and is the same size as layer We. Thus the 1980 eruption becomes representative of the mid-range of volumes rather than being in the lower range.

  18. Previous Second Trimester Abortion: A risk factor for third trimester ...

    African Journals Online (AJOL)

    Literature on spontaneous rupture of the uterus is scanty but cases occurring after hysteroscopic metroplasty, resectroscopy for Asherman´s syndrome, hysteroscopic fundal perforation, and voluntary termination of pregnancy and in a primiparous woman are reported. Spontaneous uterine rupture though rare should always ...

  19. Metastatic papillary carcinoma of the thyroid in a patient previously ...

    African Journals Online (AJOL)

    Incidental papillary carcinoma of the thyroid in patients treated surgically for benign thyroid diseases including Graves' disease is a known phenomenon. However, the management of these patients remains an issue of concern and controversy for those who care for them. We report a case of metastatic paillary carcinoma of ...

  20. Nocardia osteomyelitis in the setting of previously unknown HIV infection

    Energy Technology Data Exchange (ETDEWEB)

    Moore, Sandra Leigh [NYU Medical Center, Department of Radiology, New York, New York (United States); Jones, Sian; Lee, Julia L. [Mount Sinai Medical Center, Department of Radiology, New York, New York (United States)

    2005-01-01

    We present a case of primary Nocardia osteomyelitis in the setting of HIV infection. The clinical and radiographic manifestations of musculoskeletal nocardiosis are nonspecific and resemble those of Mycobacterium tuberculosis infection. To our knowledge no other cases of Nocardia osteomyelitis have been reported in the radiology literature. (orig.)

  1. Elijah Watt Sells Award: A Study of Previous Winners

    Science.gov (United States)

    Husted, Susan; Pinto, Joann; Romero, Silvia

    2013-01-01

    This paper reports the results of a survey of winners of the Elijah Watt Sells award. We ask them about the determinants of their success, which might be useful to other students preparing for the CPA exam. The winners graduated from different universities, not necessarily the ones ranked top, and almost all of them participated in a review…

  2. Speech and voice range profiles of adults with untrained normal voices: methodological implications.

    Science.gov (United States)

    Sanchez, Katherine; Oates, Jennifer; Dacakis, Georgia; Holmberg, Eva B

    2014-07-01

    Automatic recordings were made of speech and voice range profiles for 63 vocally healthy Australian men and women without voice training (30 males and 33 females aged 21 to 65 years). Test-retest reliability, evaluated for a subgroup, was high. Speech range profile results were consistent with results reported by others. However, voice range profiles were larger than shown in several previous studies. Nevertheless, voice range profiles were consistent with results reported for a recent study that used a similar elicitation and recording protocol and similar equipment. Results are discussed with reference to methodological issues important for reliable phonetogram recordings. The data may also be clinically useful for comparisons between disordered and healthy voices if similar equipment and elicitation and recording protocols are used.

  3. Nivolumab in previously untreated melanoma without BRAF mutation.

    Science.gov (United States)

    Robert, Caroline; Long, Georgina V; Brady, Benjamin; Dutriaux, Caroline; Maio, Michele; Mortier, Laurent; Hassel, Jessica C; Rutkowski, Piotr; McNeil, Catriona; Kalinka-Warzocha, Ewa; Savage, Kerry J; Hernberg, Micaela M; Lebbé, Celeste; Charles, Julie; Mihalcioiu, Catalin; Chiarion-Sileni, Vanna; Mauch, Cornelia; Cognetti, Francesco; Arance, Ana; Schmidt, Henrik; Schadendorf, Dirk; Gogas, Helen; Lundgren-Eriksson, Lotta; Horak, Christine; Sharkey, Brian; Waxman, Ian M; Atkinson, Victoria; Ascierto, Paolo A

    2015-01-22

    Nivolumab was associated with higher rates of objective response than chemotherapy in a phase 3 study involving patients with ipilimumab-refractory metastatic melanoma. The use of nivolumab in previously untreated patients with advanced melanoma has not been tested in a phase 3 controlled study. We randomly assigned 418 previously untreated patients who had metastatic melanoma without a BRAF mutation to receive nivolumab (at a dose of 3 mg per kilogram of body weight every 2 weeks and dacarbazine-matched placebo every 3 weeks) or dacarbazine (at a dose of 1000 mg per square meter of body-surface area every 3 weeks and nivolumab-matched placebo every 2 weeks). The primary end point was overall survival. At 1 year, the overall rate of survival was 72.9% (95% confidence interval [CI], 65.5 to 78.9) in the nivolumab group, as compared with 42.1% (95% CI, 33.0 to 50.9) in the dacarbazine group (hazard ratio for death, 0.42; 99.79% CI, 0.25 to 0.73; Psurvival was 5.1 months in the nivolumab group versus 2.2 months in the dacarbazine group (hazard ratio for death or progression of disease, 0.43; 95% CI, 0.34 to 0.56; Psurvival benefit with nivolumab versus dacarbazine was observed across prespecified subgroups, including subgroups defined by status regarding the programmed death ligand 1 (PD-L1). Common adverse events associated with nivolumab included fatigue, pruritus, and nausea. Drug-related adverse events of grade 3 or 4 occurred in 11.7% of the patients treated with nivolumab and 17.6% of those treated with dacarbazine. Nivolumab was associated with significant improvements in overall survival and progression-free survival, as compared with dacarbazine, among previously untreated patients who had metastatic melanoma without a BRAF mutation. (Funded by Bristol-Myers Squibb; CheckMate 066 ClinicalTrials.gov number, NCT01721772.).

  4. The long-term consequences of previous hyperthyroidism

    DEFF Research Database (Denmark)

    Hjelm Brandt Kristensen, Frans

    2015-01-01

    vascular state. While it is biologically plausible that these changes may induce long-term consequences, the insight into morbidity as well as mortality in patients with previous hyperthyroidism is limited. The reasons for this are a combination of inadequately powered studies, varying definitions......,400 non-hyperthyroid control individuals (matched for age and sex), all identified from a random 5% sample of the Danish background population (n=339,481). In the second study population, 625 same-sex twin pairs, discordant for hyperthyroidism, were included. For each individual, the degree of co......-up (>10 years) as well as control for co-morbidity and genetic confounding. The results provide a number of interesting insights into the long-term consequences of hyperthyroidism. Firstly, hyperthyroidism is associated with an approximately 30% increased all-cause mortality. The all-cause mortality does...

  5. MISSE Thermal Control Materials with Comparison to Previous Flight Experiments

    Science.gov (United States)

    Finckenor, Miria; Pippin, H. Gary; Frey, George

    2008-01-01

    Many different passive thermal control materials were flown as part of the Materials on International Space Station Experiment (MISSE), including inorganic coatings, anodized aluminum, and multi-layer insulation materials. These and other material samples were exposed to the low Earth orbital environment of atomic oxygen, ultraviolet radiation, thermal cycling, and hard vacuum, though atomic oxygen exposure was limited for some samples. Materials flown on MISSE-1 and MISSE-2 were exposed to the space environment for nearly four years. Materials flown on MISSE-3, MISSE-4, and MISSE-5 were exposed to the space environment for one year. Solar absorptance, infrared emittance, and mass measurements indicate the durability of these materials to withstand the space environment. Effects of short duration versus long duration exposure on ISS are explored, as well as comparable data from previous flight experiments, such as the Passive Optical Sample Assembly (POSA), Optical Properties Monitor (OPM), and Long Duration Exposure Facility (LDEF).

  6. Lessons from Previous Expeditions for the Human Exploration of Mars

    Science.gov (United States)

    Stuster, J.

    Anecdotal comparisons frequently are made between expeditions of the past and future space missions. From an engineering perspective, the differences between future and past expeditions are considerable. Spacecraft are far more complex than sailing ships, and one of the factors that drives the complexity is the requirement to support the crew in the hostile environment of space. The technological differences are significant, but from a behavioral perspective, are the differences really that great between confinement in a small wooden ship locked in the polar ice cap and confinement in a small high-technology ship hurtling through interplanetary space? The psychological differences probably are few. This paper discusses some of the most salient behavioral and technical lessons from previous expeditions that can be applied to facilitate the human explora- tion of Mars.

  7. Effect of previous induced abortions on postabortion contraception selection.

    Science.gov (United States)

    Keene, Melissa; Roston, Alicia; Keith, Louis; Patel, Ashlesha

    2015-05-01

    The objective was to compare contraceptive method selection in women undergoing their first pregnancy termination versus women undergoing repeat pregnancy termination in an urban abortion clinic. We hypothesized that women undergoing repeat abortions will select highly effective contraceptives (intrauterine device, subdermal implant, tubal ligation) more often than patients undergoing their first abortion. We conducted a retrospective analysis of all women undergoing first-trimester surgical abortion at John H. Stroger, Jr., Hospital of Cook County from October 1, 2009, to October 31, 2011. We compared contraceptive method selection in the postabortion period after receipt of contraceptive counseling for 7466 women, stratifying women by history of no prior abortion versus one or more abortions. Of the 7466 women, 48.6% (3625) had no history of previous abortion. After controlling for age, race and number of living children, women with a history of abortion were more likely to select a highly effective method [odds ratio (OR) 1.19, 95% confidence interval (CI) 1.06-1.33]. Most significantly, having living children was the strongest predictor of a highly effective method with an OR of 3.17 (95% CI 2.69-3.75). In women having a first-trimester abortion, the factors most predictive of selecting a highly effective method for postabortion contraception include history of previous abortion and having living children. The latter holds true independent of abortion history. This paper is unique in its ability to demonstrate the high interest in highly effective contraceptive selection in high-risk, low-income women with prior abortion history. Efforts to integrate provision of highly effective methods of contraception for postabortion care are essential for the reduction of future unintended pregnancies. Copyright © 2015 Elsevier Inc. All rights reserved.

  8. Typing DNA profiles from previously enhanced fingerprints using direct PCR.

    Science.gov (United States)

    Templeton, Jennifer E L; Taylor, Duncan; Handt, Oliva; Linacre, Adrian

    2017-07-01

    Fingermarks are a source of human identification both through the ridge patterns and DNA profiling. Typing nuclear STR DNA markers from previously enhanced fingermarks provides an alternative method of utilising the limited fingermark deposit that can be left behind during a criminal act. Dusting with fingerprint powders is a standard method used in classical fingermark enhancement and can affect DNA data. The ability to generate informative DNA profiles from powdered fingerprints using direct PCR swabs was investigated. Direct PCR was used as the opportunity to generate usable DNA profiles after performing any of the standard DNA extraction processes is minimal. Omitting the extraction step will, for many samples, be the key to success if there is limited sample DNA. DNA profiles were generated by direct PCR from 160 fingermarks after treatment with one of the following dactyloscopic fingerprint powders: white hadonite; silver aluminium; HiFi Volcano silk black; or black magnetic fingerprint powder. This was achieved by a combination of an optimised double-swabbing technique and swab media, omission of the extraction step to minimise loss of critical low-template DNA, and additional AmpliTaq Gold(®) DNA polymerase to boost the PCR. Ninety eight out of 160 samples (61%) were considered 'up-loadable' to the Australian National Criminal Investigation DNA Database (NCIDD). The method described required a minimum of working steps, equipment and reagents, and was completed within 4h. Direct PCR allows the generation of DNA profiles from enhanced prints without the need to increase PCR cycle numbers beyond manufacturer's recommendations. Particular emphasis was placed on preventing contamination by applying strict protocols and avoiding the use of previously used fingerprint brushes. Based on this extensive survey, the data provided indicate minimal effects of any of these four powders on the chance of obtaining DNA profiles from enhanced fingermarks. Copyright © 2017

  9. Is Previous Respiratory Disease a Risk Factor for Lung Cancer?

    Science.gov (United States)

    Denholm, Rachel; Schüz, Joachim; Straif, Kurt; Stücker, Isabelle; Jöckel, Karl-Heinz; Brenner, Darren R.; De Matteis, Sara; Boffetta, Paolo; Guida, Florence; Brüske, Irene; Wichmann, Heinz-Erich; Landi, Maria Teresa; Caporaso, Neil; Siemiatycki, Jack; Ahrens, Wolfgang; Pohlabeln, Hermann; Zaridze, David; Field, John K.; McLaughlin, John; Demers, Paul; Szeszenia-Dabrowska, Neonila; Lissowska, Jolanta; Rudnai, Peter; Fabianova, Eleonora; Dumitru, Rodica Stanescu; Bencko, Vladimir; Foretova, Lenka; Janout, Vladimir; Kendzia, Benjamin; Peters, Susan; Behrens, Thomas; Vermeulen, Roel; Brüning, Thomas; Kromhout, Hans

    2014-01-01

    Rationale: Previous respiratory diseases have been associated with increased risk of lung cancer. Respiratory conditions often co-occur and few studies have investigated multiple conditions simultaneously. Objectives: Investigate lung cancer risk associated with chronic bronchitis, emphysema, tuberculosis, pneumonia, and asthma. Methods: The SYNERGY project pooled information on previous respiratory diseases from 12,739 case subjects and 14,945 control subjects from 7 case–control studies conducted in Europe and Canada. Multivariate logistic regression models were used to investigate the relationship between individual diseases adjusting for co-occurring conditions, and patterns of respiratory disease diagnoses and lung cancer. Analyses were stratified by sex, and adjusted for age, center, ever-employed in a high-risk occupation, education, smoking status, cigarette pack-years, and time since quitting smoking. Measurements and Main Results: Chronic bronchitis and emphysema were positively associated with lung cancer, after accounting for other respiratory diseases and smoking (e.g., in men: odds ratio [OR], 1.33; 95% confidence interval [CI], 1.20–1.48 and OR, 1.50; 95% CI, 1.21–1.87, respectively). A positive relationship was observed between lung cancer and pneumonia diagnosed 2 years or less before lung cancer (OR, 3.31; 95% CI, 2.33–4.70 for men), but not longer. Co-occurrence of chronic bronchitis and emphysema and/or pneumonia had a stronger positive association with lung cancer than chronic bronchitis “only.” Asthma had an inverse association with lung cancer, the association being stronger with an asthma diagnosis 5 years or more before lung cancer compared with shorter. Conclusions: Findings from this large international case–control consortium indicate that after accounting for co-occurring respiratory diseases, chronic bronchitis and emphysema continue to have a positive association with lung cancer. PMID:25054566

  10. Surgical treatment of breast cancer in previously augmented patients.

    Science.gov (United States)

    Karanas, Yvonne L; Leong, Darren S; Da Lio, Andrew; Waldron, Kathleen; Watson, James P; Chang, Helena; Shaw, William W

    2003-03-01

    The incidence of breast cancer is increasing each year. Concomitantly, cosmetic breast augmentation has become the second most often performed cosmetic surgical procedure. As the augmented patient population ages, an increasing number of breast cancer cases among previously augmented women can be anticipated. The surgical treatment of these patients is controversial, with several questions remaining unanswered. Is breast conservation therapy feasible in this patient population and can these patients retain their implants? A retrospective review of all breast cancer patients with a history of previous augmentation mammaplasty who were treated at the Revlon/UCLA Breast Center between 1991 and 2001 was performed. During the study period, 58 patients were treated. Thirty patients (52 percent) were treated with a modified radical mastectomy with implant removal. Twenty-eight patients (48 percent) underwent breast conservation therapy, which consisted of lumpectomy, axillary lymph node dissection, and radiotherapy. Twenty-two of the patients who underwent breast conservation therapy initially retained their implants. Eleven of those 22 patients (50 percent) ultimately required completion mastectomies with implant removal because of implant complications (two patients), local recurrences (five patients), or the inability to obtain negative margins (four patients). Nine additional patients experienced complications resulting from their implants, including contracture, erosion, pain, and rupture. The data illustrate that breast conservation therapy with maintenance of the implant is not ideal for the majority of augmented patients. Breast conservation therapy with explantation and mastopexy might be appropriate for rare patients with large volumes of native breast tissue. Mastectomy with immediate reconstruction might be a more suitable choice for these patients.

  11. Somatic Cough Syndrome (Previously Referred to as Psychogenic Cough) and Tic Cough (Previously Referred to as Habit Cough) in Adults and Children: CHEST Guideline and Expert Panel Report.

    Science.gov (United States)

    Vertigan, Anne E; Murad, Mohammad H; Pringsheim, Tamara; Feinstein, Anthony; Chang, Anne B; Newcombe, Peter A; Rubin, Bruce K; McGarvey, Lorcan P; Weir, Kelly; Altman, Kenneth W; Weinberger, Miles; Irwin, Richard S; Adams, Todd M; Altman, Kenneth W; Barker, Alan F; Birring, Surinder S; Blackhall, Fiona; Bolser, Donald C; Boulet, Louis-Philippe; Braman, Sidney S; Brightling, Christopher; Callahan-Lyon, Priscilla; Canning, Brendan J; Chang, Anne B; Coeytaux, Remy; Cowley, Terrie; Davenport, Paul; Diekemper, Rebecca L; Ebihara, Satoru; El Solh, Ali A; Escalante, Patricio; Feinstein, Anthony; Field, Stephen K; Fisher, Dina; French, Cynthia T; Gibson, Peter; Gold, Philip; Gould, Michael K; Grant, Cameron; Harding, Susan M; Harnden, Anthony; Hill, Adam T; Irwin, Richard S; Kahrilas, Peter J; Keogh, Karina A; Lane, Andrew P; Lim, Kaiser; Malesker, Mark A; Mazzone, Peter; Mazzone, Stuart; McCrory, Douglas C; McGarvey, Lorcan; Molasiotis, Alex; Murad, M Hassan; Newcombe, Peter; Nguyen, Huong Q; Oppenheimer, John; Prezant, David; Pringsheim, Tamara; Restrepo, Marcos I; Rosen, Mark; Rubin, Bruce; Ryu, Jay H; Smith, Jaclyn; Tarlo, Susan M; Vertigan, Anne E; Wang, Gang; Weinberger, Miles; Weir, Kelly; Wiener, Renda Soylemez

    2015-07-01

    We conducted a systematic review on the management of psychogenic cough, habit cough, and tic cough to update the recommendations and suggestions of the 2006 guideline on this topic. We followed the American College of Chest Physicians (CHEST) methodologic guidelines and the Grading of Recommendations, Assessment, Development, and Evaluation framework. The Expert Cough Panel based their recommendations on data from the systematic review, patients' values and preferences, and the clinical context. Final grading was reached by consensus according to Delphi methodology. The results of the systematic review revealed only low-quality evidence to support how to define or diagnose psychogenic or habit cough with no validated diagnostic criteria. With respect to treatment, low-quality evidence allowed the committee to only suggest therapy for children believed to have psychogenic cough. Such therapy might consist of nonpharmacologic trials of hypnosis or suggestion therapy, or combinations of reassurance, counseling, and referral to a psychologist, psychotherapy, and appropriate psychotropic medications. Based on multiple resources and contemporary psychologic, psychiatric, and neurologic criteria (Diagnostic and Statistical Manual of Mental Disorders, 5th edition and tic disorder guidelines), the committee suggests that the terms psychogenic and habit cough are out of date and inaccurate. Compared with the 2006 CHEST Cough Guidelines, the major change in suggestions is that the terms psychogenic and habit cough be abandoned in favor of somatic cough syndrome and tic cough, respectively, even though the evidence to do so at this time is of low quality.

  12. Integrating Women into Previously All Male Air Force Units.

    Science.gov (United States)

    1980-05-31

    scales. Table 4 reports correlations of values for three different types of measures. Cadet conceptions of their masculinity and feminity are included as...essentially masculine traits? Tables 10 and 11 contain scores on the Bem masculinity and feminity scales for both the first and last years at the Academy...changes in cadet conceptions of masculinity and feminity at West Point are different than at the Air Force Academy. For example, both males and females

  13. Previous abortion and risk of pre-term birth: a population study.

    Science.gov (United States)

    Freak-Poli, Rosanne; Chan, Annabelle; Tucker, Graeme; Street, Jackie

    2009-01-01

    This population study was undertaken to determine whether previous abortion is an independent risk factor for pre-term birth and to calculate population-attributable risks for risk factors. All South Australian first singleton births in 1998-2003 (n = 42 269) were included in a multivariable logistic regression analysis, comparing pre-term births with term births. Risk factors for pre-term birth were found to be: being indigenous, single, a smoker [adjusted odds ratio (AOR) 1.28, 95% confidence interval 1.17-1.41], age 40 years or older, reproductive technology assistance, threatened miscarriage, antepartum haemorrhage, urinary tract infection, pregnancy hypertension and suspected intra-uterine growth restriction. A previous spontaneous abortion was of borderline statistical significance, whereas a previous induced abortion (AOR 1.25, 1.13-1.40) was an independent risk factor. A dose-response relationship was found with increasing number of previous spontaneous or induced abortions. Population-attributable risks were highest for pregnancy hypertension (12.4%) and antepartum haemorrhage (9.2%). Smoking and previous induced abortion had risks of 4.7% and 2.7%, respectively. Among indigenous women, 51% of whom smoked, 16.4% of pre-term birth could be attributed to smoking. A previous induced abortion and smoking during pregnancy (particularly among indigenous women) are preventable risk factors for pre-term birth. Their population-attributable risks are likely to be under-estimates from under-reporting.

  14. Combined Nivolumab and Ipilimumab or Monotherapy in Previously Untreated Melanoma

    Science.gov (United States)

    Larkin, James; Chiarion-Sileni, Vanna; Gonzalez, Rene; Grob, Jean Jacques; Cowey, C. Lance; Lao, Christopher D.; Schadendorf, Dirk; Dummer, Reinhard; Smylie, Michael; Rutkowski, Piotr; Ferrucci, Pier Francesco; Hill, Andrew; Wagstaff, John; Carlino, Matteo S.; Haanen, John B.; Maio, Michele; Marquez-Rodas, Ivan; McArthur, Grant A.; Ascierto, Paolo A.; Long, Georgina V.; Callahan, Margaret K.; Postow, Michael A.; Grossmann, Kenneth; Sznol, Mario; Dreno, Brigitte; Bastholt, Lars; Yang, Arvin; Rollin, Linda M.; Horak, Christine; Hodi, F. Stephen; Wolchok, Jedd D.

    2017-01-01

    Background The results of phase 1 and phase 2 studies suggest that nivolumab (a PD-1 checkpoint inhibitor) and ipilimumab (a CTLA-4 checkpoint inhibitor) have complementary activity in metastatic melanoma. In this randomized, double-blind, phase 3 study, nivolumab alone or nivolumab combined with ipilimumab versus ipilimumab alone were evaluated in patients with metastatic melanoma. Methods We randomly assigned 945 previously untreated patients with unresectable stage III or IV melanoma, in 1:1:1 ratio, to nivolumab alone (3 mg per kilogram of body weight every 2 weeks), or to nivolumab (at a dose of 1 mg per kilogram) plus ipilimumab (at a dose of 3 mg per kilogram) every 3 weeks for 4 doses followed by nivolumab (3 mg per kilogram every 2 weeks), or to ipilimumab alone (3 mg per kilogram every 3 weeks for 4 doses). Progression-free and overall survival were co-primary end points. Patients continue to be followed for overall survival. Results Median progression-free survival was 11.5 months (95% confidence interval [CI], 8.9 to 16.7) for nivolumab plus ipilimumab as compared with 2.9 months (95% CI, 2.8 to 3.4) for ipilimumab alone (hazard ratio, 0.42; 95% CI, 0.31 to 0.57; Pnivolumab alone (hazard ratio in the comparison with ipilimumab alone, 0.57; 95% CI, 0.43 to 0.76; Pnivolumab plus ipilimumab and nivolumab alone groups, but in PD-L1-negative patients, progression-free survival was longer with the combination as compared with nivolumab alone (11.2 months [95% CI, 8.0 to not reached] versus 5.3 months [95% CI, 2.8 to 7.1]). Grade 3–4 drug-related adverse events occurred in 16.3%, 55.0%, and 27.3% of patients in the nivolumab, nivolumab plus ipilimumab, and ipilimumab alone groups, with 1, 0, and 1 drug-related deaths, respectively. Conclusions Nivolumab alone or combined with ipilimumab significantly improved progression-free survival, as compared with ipilimumab, among previously untreated patients with metastatic melanoma. Results with the combination

  15. 76 FR 6525 - Airworthiness Directives; Cessna Aircraft Company (Type Certificate Previously Held by Columbia...

    Science.gov (United States)

    2011-02-07

    ... Company (Type Certificate Previously Held by Columbia Aircraft Manufacturing (Previously the Lancair... Aircraft Company (Type Certificate Previously Held by Columbia Aircraft Manufacturing (Previously The... Aircraft Company (type certificate previously held by Columbia Aircraft Manufacturing (previously The...

  16. Telangiectatic oncocytoma: a previously undescribed variant of renal oncocytoma.

    Science.gov (United States)

    Xiao, Guang-Qian; Ko, Huai-Bin Mabel; Unger, Pamela

    2013-07-01

    To identify, describe, and investigate the clinical, radiologic, and pathologic features of 8 cases of telangiectatic oncocytoma. Fifty-three consecutive renal oncocytomas were reviewed for the telangiectatic pathologic features that were subsequently correlated with the demographic, clinical, and radiographic findings. Telangiectatic oncocytoma accounted for 15% of the 53 renal oncocytomas collected in the past 7 years in our institution. On radiology, almost all presented as an enhancing mass and were suspicious for or consistent with a renal malignant tumor. Grossly, the tumors ranged from 2.4 to 6.0 cm (mean, 3.5 cm) and macroscopically were hemorrhagic spongy or multicystic masses without a central stellate scar. Microscopically, they were characterized by variably sized blood-distended spaces (oncocytoma cells and without evidence of degenerative changes. With its unique radiologic and pathologic presentations in comparison with classic renal oncocytoma, it is important to recognize this new variant of renal oncocytoma.

  17. Is previous hyperthyroidism associated with long-term cognitive dysfunction?

    DEFF Research Database (Denmark)

    Lillevang-Johansen, Mads; Petersen, Inge; Christensen, Kaare

    2014-01-01

    OBJECTIVE: Hyperthyroidism has been suggested to adversely affect cognitive function. However, this association could also be caused by genetic and environmental factors affecting both the development of hyperthyroidism and cognitive functioning. By investigating twin pairs discordant...... for hyperthyroidism, this potential confounding can be minimized. The aim of the study was to examine if hyperthyroidism is associated with long-term cognitive dysfunction. DESIGN: Twin case-control study. PATIENTS: Twin pairs discordant for hyperthyroidism were identified by record-linkage between The Danish...... tests. Based on five of the tests a composite cognitive score was calculated. RESULTS: 55 out of 3036 twin pairs were discordant for hyperthyroidism. The mean time from diagnosis until survey participation was 7.3 years (range: 0-24.1 years). In both the intra-pair and individual level analyses...

  18. MEMS variable capacitance devices utilizing the substrate: I. Novel devices with a customizable tuning range

    KAUST Repository

    Elshurafa, Amro M.

    2010-03-22

    This paper, the first in a series of two, presents a paradigm shift in the design of MEMS parallel plate PolyMUMPS variable capacitance devices by proposing two structures that utilize the substrate and are able to provide predetermined, customizable, tuning ranges and/or ratios. The proposed structures can provide theoretical tuning ranges anywhere from 4.9 to 35 and from 3.4 to 26 respectively with a simple, yet effective, layout modification as opposed to the previously reported devices where the tuning range is fixed and cannot be varied. Theoretical analysis is carried out and verified with measurements of fabricated devices. The first proposed device possessed initially a tuning range of 4.4. Two variations of the structure having tuning ranges of 3 and 3.4, all at 1 GHz, were also successfully developed and tested. The second proposed variable capacitance device behaved as a switch. © 2010 IOP Publishing Ltd.

  19. Multispecies Coevolution Particle Swarm Optimization Based on Previous Search History

    Directory of Open Access Journals (Sweden)

    Danping Wang

    2017-01-01

    Full Text Available A hybrid coevolution particle swarm optimization algorithm with dynamic multispecies strategy based on K-means clustering and nonrevisit strategy based on Binary Space Partitioning fitness tree (called MCPSO-PSH is proposed. Previous search history memorized into the Binary Space Partitioning fitness tree can effectively restrain the individuals’ revisit phenomenon. The whole population is partitioned into several subspecies and cooperative coevolution is realized by an information communication mechanism between subspecies, which can enhance the global search ability of particles and avoid premature convergence to local optimum. To demonstrate the power of the method, comparisons between the proposed algorithm and state-of-the-art algorithms are grouped into two categories: 10 basic benchmark functions (10-dimensional and 30-dimensional, 10 CEC2005 benchmark functions (30-dimensional, and a real-world problem (multilevel image segmentation problems. Experimental results show that MCPSO-PSH displays a competitive performance compared to the other swarm-based or evolutionary algorithms in terms of solution accuracy and statistical tests.

  20. Use of robotic colonoscopy in patients with previous incomplete colonoscopy.

    Science.gov (United States)

    Tumino, E; Parisi, G; Bertoni, M; Bertini, M; Metrangolo, S; Ierardi, E; Cervelli, R; Bresci, G; Sacco, R

    2017-02-01

    Conventional colonoscopy (CC) is the gold standard to diagnostic and therapeutic approach to colon. However, in few cases, cecal intubation could fail due to colon anatomy, patient compliance and physician expertise. Endotics robotic colonoscopy is a novel, safe, mini-invasive modality to explore the entire colon. Our aim was to assess, in a retrospective study, Endotics ability of cecal intubation in all cases in which CC failed. Between January 2008 and December 2012, 276 Endotics robotic colonscopy examinations were performed at the Gastroenterology and Metabolic Diseases Unit of Pisa University Hospital, Pisa, Italy, in a series of consecutive patients who had undergone CC and failed cecal intubation. We assessed the cecal intubation rate in 102 patients addressed to Endotics after previous incomplete CC. Overall, endotics system was successful in 93.1% of the incomplete conventional colonoscopy cases (95% performance). Whenever the intended exploration of the entire colon with CC failed, the endotics robotic endoscopy represented a useful tool as it helped examine the entire colon in almost all cases.

  1. Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins.

    Directory of Open Access Journals (Sweden)

    Pingzhao Hu

    2009-04-01

    Full Text Available One-third of the 4,225 protein-coding genes of Escherichia coli K-12 remain functionally unannotated (orphans. Many map to distant clades such as Archaea, suggesting involvement in basic prokaryotic traits, whereas others appear restricted to E. coli, including pathogenic strains. To elucidate the orphans' biological roles, we performed an extensive proteomic survey using affinity-tagged E. coli strains and generated comprehensive genomic context inferences to derive a high-confidence compendium for virtually the entire proteome consisting of 5,993 putative physical interactions and 74,776 putative functional associations, most of which are novel. Clustering of the respective probabilistic networks revealed putative orphan membership in discrete multiprotein complexes and functional modules together with annotated gene products, whereas a machine-learning strategy based on network integration implicated the orphans in specific biological processes. We provide additional experimental evidence supporting orphan participation in protein synthesis, amino acid metabolism, biofilm formation, motility, and assembly of the bacterial cell envelope. This resource provides a "systems-wide" functional blueprint of a model microbe, with insights into the biological and evolutionary significance of previously uncharacterized proteins.

  2. Motivational activities based on previous knowledge of students

    Science.gov (United States)

    García, J. A.; Gómez-Robledo, L.; Huertas, R.; Perales, F. J.

    2014-07-01

    Academic results depend strongly on the individual circumstances of students: background, motivation and aptitude. We think that academic activities conducted to increase motivation must be tuned to the special situation of the students. Main goal of this work is analyze the students in the first year of the Degree in Optics and Optometry in the University of Granada and the suitability of an activity designed for those students. Initial data were obtained from a survey inquiring about the reasons to choose this degree, their knowledge of it, and previous academic backgrounds. Results show that: 1) the group is quite heterogeneous, since students have very different background. 2) Reasons to choose the Degree in Optics and Optometry are also very different, and in many cases were selected as a second option. 3) Knowledge and motivations about the Degree are in general quite low. Trying to increase the motivation of the students we designed an academic activity in which we show different topics studied in the Degree. Results show that students that have been involved in this activity are the most motivated and most satisfied with their election of the degree.

  3. Abiraterone in metastatic prostate cancer without previous chemotherapy.

    Science.gov (United States)

    Ryan, Charles J; Smith, Matthew R; de Bono, Johann S; Molina, Arturo; Logothetis, Christopher J; de Souza, Paul; Fizazi, Karim; Mainwaring, Paul; Piulats, Josep M; Ng, Siobhan; Carles, Joan; Mulders, Peter F A; Basch, Ethan; Small, Eric J; Saad, Fred; Schrijvers, Dirk; Van Poppel, Hendrik; Mukherjee, Som D; Suttmann, Henrik; Gerritsen, Winald R; Flaig, Thomas W; George, Daniel J; Yu, Evan Y; Efstathiou, Eleni; Pantuck, Allan; Winquist, Eric; Higano, Celestia S; Taplin, Mary-Ellen; Park, Youn; Kheoh, Thian; Griffin, Thomas; Scher, Howard I; Rathkopf, Dana E

    2013-01-10

    Abiraterone acetate, an androgen biosynthesis inhibitor, improves overall survival in patients with metastatic castration-resistant prostate cancer after chemotherapy. We evaluated this agent in patients who had not received previous chemotherapy. In this double-blind study, we randomly assigned 1088 patients to receive abiraterone acetate (1000 mg) plus prednisone (5 mg twice daily) or placebo plus prednisone. The coprimary end points were radiographic progression-free survival and overall survival. The study was unblinded after a planned interim analysis that was performed after 43% of the expected deaths had occurred. The median radiographic progression-free survival was 16.5 months with abiraterone-prednisone and 8.3 months with prednisone alone (hazard ratio for abiraterone-prednisone vs. prednisone alone, 0.53; 95% confidence interval [CI], 0.45 to 0.62; Pchemotherapy, opiate use for cancer-related pain, prostate-specific antigen progression, and decline in performance status. Grade 3 or 4 mineralocorticoid-related adverse events and abnormalities on liver-function testing were more common with abiraterone-prednisone. Abiraterone improved radiographic progression-free survival, showed a trend toward improved overall survival, and significantly delayed clinical decline and initiation of chemotherapy in patients with metastatic castration-resistant prostate cancer. (Funded by Janssen Research and Development, formerly Cougar Biotechnology; ClinicalTrials.gov number, NCT00887198.).

  4. Influence of Previous Knowledge in Torrance Tests of Creative Thinking

    Directory of Open Access Journals (Sweden)

    María Aranguren

    2015-07-01

    Full Text Available The aim of this work is to analyze the influence of study field, expertise and recreational activities participation in Torrance Tests of Creative Thinking (TTCT, 1974 performance. Several hypotheses were postulated to explore the possible effects of previous knowledge in TTCT verbal and TTCT figural university students’ outcomes. Participants in this study included 418 students from five study fields: Psychology;Philosophy and Literature, Music; Engineering; and Journalism and Advertising (Communication Sciences. Results found in this research seem to indicate that there in none influence of the study field, expertise and recreational activities participation in neither of the TTCT tests. Instead, the findings seem to suggest some kind of interaction between certain skills needed to succeed in specific studies fields and performance on creativity tests, such as the TTCT. These results imply that TTCT is a useful and valid instrument to measure creativity and that some cognitive process involved in innovative thinking can be promoted using different intervention programs in schools and universities regardless the students study field.

  5. Optimization and limits of electrostatic sorting by bi-polar charge of mineral mixtures in the fine grain size range. Final report. Optimierung und Grenzen der elektrostatischen Sortierung durch bipolare Aufladung von Mineralgemischen im Feinkornbereich. Schlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    1988-01-01

    In this work, the charge distribution in mineral mixtures and the electrostatic sorting according to tribo-charging is examined on R-10 fractions in the particle size range of 50-200 {mu}m. The purpose of the investigations was combinations of pairs from quartz, calcite, heavy spar, river spar and the pairing anthracite/quartz. Separation experiments were also carried out for the quartz/calcite pair in the particle size range of 20-50 {mu}m. After a survey of the literature and the electrical processes in the contact of two materials, some theoretical considerations procede the investigations, which are concerned with the maximum surface charge density on particles, the electrostatic agglomeration and the calculation of particle track curves in an homogeneous electrical field. It is shown that in principle, electrostatic agglomerates can always be separated in an electrical field. (orig.).

  6. Rosiglitazone and myocardial infarction in patients previously prescribed metformin.

    Directory of Open Access Journals (Sweden)

    Colin R Dormuth

    Full Text Available OBJECTIVE: Rosiglitazone was found associated with approximately a 43% increase in risk of acute myocardial infarction (AMI in a two meta-analyses of clinical trials. Our objective is to estimate the magnitude of the association in real-world patients previously treated with metformin. RESEARCH DESIGN AND METHODS: We conducted a nested case control study in British Columbia using health care databases on 4.3 million people. Our cohort consisted of 158,578 patients with Type 2 diabetes who used metformin as first-line drug treatment. We matched 2,244 cases of myocardial infarction (AMI with up to 4 controls. Conditional logistic regression models were used to estimate matched odds ratios for AMI associated with treatment with rosiglitazone, pioglitazone and sulfonylureas. RESULTS: In our cohort of prior metformin users, adding rosiglitazone for up to 6 months was not associated with an increased risk of AMI compared to adding a sulfonylurea (odds ratio [OR] 1.38; 95% confidence interval [CI], 0.91-2.10, or compared to adding pioglitazone (OR for rosi versus pio 1.41; 95% CI, 0.74-2.66. There were also no significant differences between rosiglitazone, pioglitazone and sulfonylureas for longer durations of treatment. Though not significantly different from sulfonylureas, there was a transient increase in AMI risk associated with the first 6 months of treatment with a glitazone compared to not using the treatment (OR 1.53; 95% CI, 1.13-2.07 CONCLUSIONS: In our British Columbia cohort of patients who received metformin as first-line pharmacotherapy for Type 2 diabetes mellitus, further treatment with rosiglitazone did not increase the risk of AMI compared to patients who were treated with pioglitazone or a sulfonylurea. Though not statistically significantly different compared from each other, an increased risk of AMI observed after starting rosiglitazone or sulfonylureas is a matter of concern that requires more research.

  7. Repeat immigration: A previously unobserved source of heterogeneity?

    Science.gov (United States)

    Aradhya, Siddartha; Scott, Kirk; Smith, Christopher D

    2017-07-01

    Register data allow for nuanced analyses of heterogeneities between sub-groups which are not observable in other data sources. One heterogeneity for which register data is particularly useful is in identifying unique migration histories of immigrant populations, a group of interest across disciplines. Years since migration is a commonly used measure of integration in studies seeking to understand the outcomes of immigrants. This study constructs detailed migration histories to test whether misclassified migrations may mask important heterogeneities. In doing so, we identify a previously understudied group of migrants called repeat immigrants, and show that they differ systematically from permanent immigrants. In addition, we quantify the degree to which migration information is misreported in the registers. The analysis is carried out in two steps. First, we estimate income trajectories for repeat immigrants and permanent immigrants to understand the degree to which they differ. Second, we test data validity by cross-referencing migration information with changes in income to determine whether there are inconsistencies indicating misreporting. From the first part of the analysis, the results indicate that repeat immigrants systematically differ from permanent immigrants in terms of income trajectories. Furthermore, income trajectories differ based on the way in which years since migration is calculated. The second part of the analysis suggests that misreported migration events, while present, are negligible. Repeat immigrants differ in terms of income trajectories, and may differ in terms of other outcomes as well. Furthermore, this study underlines that Swedish registers provide a reliable data source to analyze groups which are unidentifiable in other data sources.

  8. Previously unidentified morbidity in patients with intellectual disability

    Science.gov (United States)

    Baxter, Helen; Lowe, Kathy; Houston, Helen; Jones, Glyn; Felce, David; Kerr, Michael

    2006-01-01

    Background Adults with a learning disability frequently have unmet health needs. The cause for this is complex and may be related to difficulties in accessing usual primary care services. Health checks have been widely recommended as a solution to this need. Aim To determine the likelihood that a structured health check by the primary care team supported by appropriate education would identify and treat previously unrecognised morbidity in adults with an intellectual disability. Design of study Individuals were identified within primary care teams and a structured health check performed by the primary care team. This process was supported by an educational resource. Face-to-face audit with the team was performed 3 months following the check. Setting Forty general practices within three health authorities in south and mid-Wales participated. They had a combined registered patient population of 354 000. Method Health checks were conducted for 190 (60%) of 318 identified individuals; 128 people moved, died, withdrew from the study, or refused to participate. Results Complete data were available on 181 health checks; 51% had new needs recognised, of whom 63% had one health need, 25% two health needs, and 12% more than two. Sixteen patients (9%) had serious new morbidity discovered. Management had been initiated for 93% of the identified health needs by the time of audit. This study is the first to identify new disease findings in a primary care population and the likelihood that such disease will be treated. Conclusions The findings reflect a concern that current care delivery leaves adults with an intellectual disability at risk of both severe and milder illness going unrecognised. Health checks present one mechanism for identifying and treating such illness in primary care. PMID:16464321

  9. Sacrococcygeal pilonidal disease: analysis of previously proposed risk factors

    Directory of Open Access Journals (Sweden)

    Ali Harlak

    2010-01-01

    Full Text Available PURPOSE: Sacrococcygeal pilonidal disease is a source of one of the most common surgical problems among young adults. While male gender, obesity, occupations requiring sitting, deep natal clefts, excessive body hair, poor body hygiene and excessive sweating are described as the main risk factors for this disease, most of these need to be verified with a clinical trial. The present study aimed to evaluate the value and effect of these factors on pilonidal disease. METHOD: Previously proposed main risk factors were evaluated in a prospective case control study that included 587 patients with pilonidal disease and 2,780 healthy control patients. RESULTS: Stiffness of body hair, number of baths and time spent seated per day were the three most predictive risk factors. Adjusted odds ratios were 9.23, 6.33 and 4.03, respectively (p<0.001. With an adjusted odds ratio of 1.3 (p<.001, body mass index was another risk factor. Family history was not statistically different between the groups and there was no specific occupation associated with the disease. CONCLUSIONS: Hairy people who sit down for more than six hours a day and those who take a bath two or less times per week are at a 219-fold increased risk for sacrococcygeal pilonidal disease than those without these risk factors. For people with a great deal of hair, there is a greater need for them to clean their intergluteal sulcus. People who engage in work that requires sitting in a seat for long periods of time should choose more comfortable seats and should also try to stand whenever possible.

  10. Total knee arthroplasty in patients with a previous patellectomy.

    Science.gov (United States)

    Maslow, Jed; Zuckerman, Joseph D; Immerman, Igor

    2013-01-01

    Post-patellectomy patients represent a specific subgroup of patients that may develop arthritis and persistent knee pain and potentially require treatment with total knee arthroplasty. This article reviews the treatment and functional outcomes following total knee arthroplasty in patients with prior patellectomy. A case report is presented as an example of the clinical management of a post-patellectomy patient with significant knee pain and disability treated with total knee arthroplasty. Emphasis will be placed in decision- making, specifically with the use of a posterior stabilized implant. In addition, postoperative strengthening of the quadriceps is essential to compensate for the lack of the patella and increase the success of total knee arthroplasty in this subgroup of patients.

  11. [Granulomatosis with polyangiitis (previously Wegener's granulomatosis) mimicking malingering].

    Science.gov (United States)

    Ene, N; Bélénotti, P; Benyamine, A; Sovaila, S; Ben Sahla Talet, M H; Kaminsky, P; Serratrice, J; Weiller, P-J

    2014-08-01

    ANCA vasculitis may involve the skin and develop slowly without specific histology, and without autoantibodies. We report a 50-year-old woman who experienced bilateral mastectomy because of ulcero-necrotic, non-specific inflammatory cutaneous lesions of the breasts. First considered by others as a malinger patient, she developed oto-neurological lesions leading to the diagnosis of Wegener's granulomatosis. Five years later, specific antibodies of the disease were present. Cutaneous involvement by ANCA vasculitis can be isolated for a long time. Physicians must have a high degree of suspicion to avoid diagnostic delay of ANCA vasculitis. Copyright © 2013 Société nationale française de médecine interne (SNFMI). Published by Elsevier SAS. All rights reserved.

  12. Current trends in trachoma in a previously Hyperendemic area

    Directory of Open Access Journals (Sweden)

    Study Group The Trachoma

    1998-01-01

    Full Text Available In response to reports of an excessive number of cases of trachoma at the end of 1995 from the western parts of the North Indian state of Uttar Pradesh, 837 children in the age-group 1-10 years were examined in three villages from where the maximum number of cases hailed. Clinically, the prevalence of trachoma was found to be 8.5% (71. The prevalence was significantly higher in males as compared to females (p < 0.05; and was observed to increase with age. 85.9% (61 of the clinically diagnosed children were active infective cases. 54.9% (39 of the clinically diagnosed cases showed the presence of antigen in the upper tarsal conjunctival scraping from the affected eye, using the Chlamydia trachomatis direct specimen kit (Syva MicroTrak, UK. It was concluded that ophthalmologists must be reoriented to the clinical diagnosis of trachoma to prevent overdiagnosis.

  13. Recurrent severe invasive pneumococcal disease in an adult with previously unknown hyposplenia

    DEFF Research Database (Denmark)

    Ballegaard, Vibe C; Schejbel, Lone; Hoffmann, Steen

    2015-01-01

    of meningitis and developed sufficient levels of pneumococcal antibodies. The pneumococcal strains isolated were serotype 7 F and 17 F. To our knowledge, there has been no previously reported case of recurrent invasive pneumococcal disease in a pneumococcal vaccinated adult with hyposplenia and apparently...... was found. Despite immunization against S. pneumoniae and measurement of what was interpreted as protective levels of serotype-specific IgG antibodies after vaccination, the patient suffered from a third episode of IPD. CONCLUSIONS: Individuals with predisposing medical conditions or a history of severe......BACKGROUND: The risk of life-threatening and invasive infections with encapsulated bacteria is increased in patients with hyposplenia or asplenia. We report a case of recurrent invasive pneumococcal meningitis in a woman with previous unknown hyposplenia. She was vaccinated after the first episode...

  14. Echinocandin Failure Case Due to a Previously Unreported FKS1 Mutation in Candida krusei

    DEFF Research Database (Denmark)

    Jensen, Rasmus Hare; Justesen, Ulrik Stenz; Rewes, Annika

    2014-01-01

    Echinocandins are the preferred therapy for invasive infections due to Candida krusei. We present here a case of clinical failure involving C. krusei with a characteristic FKS1 hot spot mutation not previously reported in C. krusei that was isolated after 14 days of treatment. Anidulafungin MICs ...... were elevated by ≥5 dilution steps above the clinical breakpoint but by only 1 step for a Candida albicans isolate harboring the corresponding mutation, suggesting a notable species-specific difference in the MIC increase conferred by this mutation.......Echinocandins are the preferred therapy for invasive infections due to Candida krusei. We present here a case of clinical failure involving C. krusei with a characteristic FKS1 hot spot mutation not previously reported in C. krusei that was isolated after 14 days of treatment. Anidulafungin MICs...

  15. Electrophile-Integrating Smiles Rearrangement Provides Previously Inaccessible C4?-O-Alkyl Heptamethine Cyanine Fluorophores

    OpenAIRE

    Nani, Roger R.; Shaum, James B.; Gorka, Alexander P.; Schnermann, Martin J.

    2015-01-01

    New synthetic methods to rapidly access useful fluorophores are needed to advance modern molecular imaging techniques. A new variant of the classical Smiles rearrangement is reported that enables the efficient synthesis of previously inaccessible C4?-O-alkyl heptamethine cyanines. The key reaction involves N- to O- transposition with selective electrophile incorporation on nitrogen. A representative fluorophore exhibits excellent resistance to thiol nucleophiles, undergoes productive bioconju...

  16. Electrophile-integrating Smiles rearrangement provides previously inaccessible C4'-O-alkyl heptamethine cyanine fluorophores.

    Science.gov (United States)

    Nani, Roger R; Shaum, James B; Gorka, Alexander P; Schnermann, Martin J

    2015-01-16

    New synthetic methods to rapidly access useful fluorophores are needed to advance modern molecular imaging techniques. A new variant of the classical Smiles rearrangement is reported that enables the efficient synthesis of previously inaccessible C4'-O-alkyl heptamethine cyanines. The key reaction involves N- to O-transposition with selective electrophile incorporation on nitrogen. A representative fluorophore exhibits excellent resistance to thiol nucleophiles, undergoes productive bioconjugation, and can be used in near-IR fluorescence imaging applications.

  17. Outpatient parenteral antimicrobial therapy for surgery patients: A comparison with previous standard of care

    OpenAIRE

    Anjie Yang; Ron Fung; James Brunton; Linda Dresser

    2013-01-01

    BACKGROUND: Current literature reports that outpatient parenteral antimicrobial therapy (OPAT) programs improve cure rates, and reduce length of hospitalization and costs. OPAT programs are still relatively new in Canada.OBJECTIVE: To evaluate the benefits of an OPAT program initiated at a multispecialty tertiary care facility in Toronto, Ontario, compared with the previous standard of care.METHODS: The present retrospective observational study was conducted using data from a group of surgica...

  18. Pulmonary Aspergillosis in a Previously Healthy 13-Year-Old Boy

    Directory of Open Access Journals (Sweden)

    Jonathan H. Rayment

    2016-01-01

    Full Text Available Chronic granulomatous disease (CGD is a rare, polygenic primary immunodeficiency. In this case report, we describe a previously healthy 13-year-old boy who presented with multifocal pulmonary aspergillosis and was subsequently diagnosed with an autosomal recessive form of chronic granulomatous disease. CGD has a variable natural history and age of presentation and should be considered when investigating a patient with recurrent or severe infections with catalase-positive organisms.

  19. Reduced infection in mosquitoes exposed to blood meals containing previously frozen flaviviruses

    OpenAIRE

    Richards, Stephanie L.; Pesko, Kendra; Barry W Alto; Mores, Christopher N.

    2007-01-01

    The increased difficulty and expense of using live animals for delivering infectious blood meals in arthropod-borne virus vector competence experiments has resulted in an increase in the use of artificial feeding systems. Compared to live hosts, artificial systems require higher viral titers to attain mosquito infection, thereby limiting the utility of such systems with low or moderate titer virus stocks. Based on the report that freshly propagated virus is more infectious than previously fro...

  20. The Yellowstone magma reservoir is 50% larger than previously imaged

    Science.gov (United States)

    Farrell, J.; Smith, R. B.; Husen, S.

    2013-12-01

    Earlier tomographic studies of the Yellowstone crustal magma system have revealed a low P-wave crustal anomaly beneath the 0.64 Ma Yellowstone caldera that has been interpreted to be the magma reservoir of partial melt that provides the thermal energy for Yellowstone's youthful volcanic and hydrothermal systems. The Yellowstone seismic network has evolved over the last decade into a modern real-time volcano monitoring system that consists of 36 short-period, broadband, and borehole seismometers that cover the entire Yellowstone volcanic field and surrounding tectonic areas. Until recently, limited seismograph coverage did not provide for adequate resolution of the velocity structure northeast of the caldera, an area of the largest negative Bouguer gravity field of -60 mGal whose 3D density model reveals a shallow, low density body that extends ~20 km northeast of the caldera. Recent upgrades to the Yellowstone Seismic Network (YSN), including the addition of nine 3-component and broadband seismic stations providing much better ray coverage of the entire Yellowstone area with greater bandwidth data. This allows much-expanded and improved resolution coverage of the Yellowstone crustal velocity structure. We have compiled waveforms for the Yellowstone earthquake catalog from 1984-2011 with 45,643 earthquakes and 1,159,724 waveforms to analyze P-wave arrival times with an automatic picker based on an adaptive high-fidelity human mimicking algorithm. Our analysis reduced the data to the 4,520 best-located earthquakes with 48,622 P-wave arrival times to invert for the velocity structure. The resulting 3D P-wave model reveals a low Vp body (up to -7% ΔVp) that is interpreted to be the Yellowstone crustal magma reservoir and is ~50% larger than previously imaged. It extends as an oblong shaped anomalous body ~90 km NE-SW, ~20 km NE of the 0.64 Ma caldera, and up to 30 km wide and markedly shallowing from 15 km depth beneath the caldera to less than ~2 km deep northeast of

  1. Listeria monocytogenes meningoencephalitis in an immunocompetent, previously healthy 20-month old female child

    Directory of Open Access Journals (Sweden)

    Peer M

    2010-01-01

    Full Text Available Invasive listeriosis predominantly affects pregnant women, neonates, elderly and people with a compromised immune function. For more than 80 years since the discovery of Listeria in 1924, only a few reports of invasive listeriosis in humans have emerged from India, with all of them in patients having an underlying predisposition. We, however, report Listeria monocytogenes meningoencephalitis in an immunocompetent, previously healthy, 20-month-old female child with no underlying predisposition. The patient showed poor response to empirical treatment with vancomycin and ceftriaxone but improved dramatically after substitution with ampicillin and amikacin. She had a complete recovery other than left lateral rectus palsy that persisted.

  2. Listeria monocytogenes meningoencephalitis in an immunocompetent, previously healthy 20-month old female child.

    Science.gov (United States)

    Peer, M A; Nasir, R A; Kakru, D K; Fomda, B A; Wani, M A; Hakeem, Q N

    2010-01-01

    Invasive listeriosis predominantly affects pregnant women, neonates, elderly and people with a compromised immune function. For more than 80 years since the discovery of Listeria in 1924, only a few reports of invasive listeriosis in humans have emerged from India, with all of them in patients having an underlying predisposition. We, however, report Listeria monocytogenes meningoencephalitis in an immunocompetent, previously healthy, 20-month-old female child with no underlying predisposition. The patient showed poor response to empirical treatment with vancomycin and ceftriaxone but improved dramatically after substitution with ampicillin and amikacin. She had a complete recovery other than left lateral rectus palsy that persisted.

  3. Anaesthetic management for caesarean section in a case of previously operated with residual pituitary tumour

    Directory of Open Access Journals (Sweden)

    Prerana N Shah

    2011-01-01

    Full Text Available Successful anaesthetic management for caesarean section in a case with previous pituitary tumour resection, with residual tumour, is reported. The pituitary gland undergoes global hyperplasia during pregnancy. Functional pituitary tumours may exhibit symptomatic enlargement during pregnancy. Growth hormone secreting tumour is associated with acromegaly which has associated anaesthetic implications of difficult airway, systemic hypertension, and diabetes and electrolyte imbalance. Intracranial space occupying lesions can increase intra cranial pressure and compromise cerebral perfusion or cause herniation. We report management of this case.

  4. Final report: Bilateral key comparison SIM.T-K6.3 on humidity standards in the dew/frost-point temperature range from -30°C to 20°C

    Science.gov (United States)

    Huang, Peter; Meyer, Christopher; Brionizio, Julio D.

    2015-01-01

    A Regional Metrology Organization (RMO) Key Comparison of dew/frost point temperatures was carried out by the National Institute of Standards and Technology (NIST, USA) and the Instituto Nacional de Metrologia, Qualidade e Tecnologia (INMETRO, Brazil) between October 2009 and March 2010. The results of this comparison are reported here, along with descriptions of the humidity laboratory standards for NIST and INMETRO and the uncertainty budget for these standards. This report also describes the protocol for the comparison and presents the data acquired. The results are analyzed, determining degree of equivalence between the dew/frost-point standards of NIST and INMETRO. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCT, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

  5. Corrective Action Decision Document/Closure Report for Corrective Action Unit 541: Small Boy Nevada National Security Site and Nevada Test and Training Range, Nevada, Revision 0 with ROTC-1

    Energy Technology Data Exchange (ETDEWEB)

    Kidman, Raymond [Navarro, Las Vegas, NV (United States); Matthews, Patrick [Navarro, Las Vegas, NV (United States)

    2016-08-01

    The purpose of this Corrective Action Decision Document/Closure Report is to provide justification and documentation supporting the recommendation that no further corrective action is needed for CAU 541 based on the no further action alternative listed in Table ES-1.

  6. Report to the DOE nuclear data committee. [EV RANGE 10-100; CROSS SECTIONS; PHOTONEUTRONS; NEUTRONS; GAMMA RADIATION; COUPLED CHANNEL THEORY; DIFFERENTIAL CROSS SECTIONS; MEV RANGE 01-10; ; CAPTURE; GAMMA SPECTRA; THERMAL NEUTRONS; COMPUTER CALCULATIONS; DECAY; FISSION PRODUCTS; FISSION YIELD; SHELL MODELS; NUCLEAR DATA COLLECTIONS

    Energy Technology Data Exchange (ETDEWEB)

    Struble, G.L.; Haight, R.C.

    1981-03-01

    Topics covered include: studies of (n, charged particle) reactions with 14 to 15 MeV neutrons; photoneutron cross sections for /sup 15/N; neutron radiative capture; Lane-model analysis of (p,p) and (n,n) scattering on the even tin isotopes; neutron scattering cross sections for /sup 181/Ta, /sup 197/Au, /sup 209/Bi, /sup 232/Th, and /sup 238/U inferred from proton scattering and charge exchange cross sections; neutron-induced fission cross sections of /sup 245/Cm and /sup 242/Am; fission neutron multiplicities for /sup 245/Cm and /sup 242/Am; the transport of 14 MeV neutrons through heavy materials 150 < A < 208; /sup 249/Cm energy levels from measurement of thermal neutron capture gamma rays; /sup 231/Th energy levels from neutron capture gamma ray and conversion electron spectroscopy; new measurements of conversion electron binding energies in berkelium and californium; nuclear level densities; relative importance of statistical vs. valence neutron capture in the mass-90 region; determination of properties of short-lived fission products; fission yield of /sup 87/Br and /sup 137/I from 15 nuclei ranging from /sup 232/Th to /sup 249/Cf; evaluation of charged particle data for the ECPL library; evaluation of secondary charged-particle energy and angular distributions for ENDL; and evaluated nuclear structure libraries derived from the table of isotopes. (GHT)

  7. Do emotional intelligence and previous caring experience influence student nurse performance? A comparative analysis.

    Science.gov (United States)

    Stenhouse, Rosie; Snowden, Austyn; Young, Jenny; Carver, Fiona; Carver, Hannah; Brown, Norrie

    2016-08-01

    Reports of poor nursing care have focused attention on values based selection of candidates onto nursing programmes. Values based selection lacks clarity and valid measures. Previous caring experience might lead to better care. Emotional intelligence (EI) might be associated with performance, is conceptualised and measurable. To examine the impact of 1) previous caring experience, 2) emotional intelligence 3) social connection scores on performance and retention in a cohort of first year nursing and midwifery students in Scotland. A longitudinal, quasi experimental design. Adult and mental health nursing, and midwifery programmes in a Scottish University. Adult, mental health and midwifery students (n=598) completed the Trait Emotional Intelligence Questionnaire-short form and Schutte's Emotional Intelligence Scale on entry to their programmes at a Scottish University, alongside demographic and previous caring experience data. Social connection was calculated from a subset of questions identified within the TEIQue-SF in a prior factor and Rasch analysis. Student performance was calculated as the mean mark across the year. Withdrawal data were gathered. 598 students completed baseline measures. 315 students declared previous caring experience, 277 not. An independent-samples t-test identified that those without previous caring experience scored higher on performance (57.33±11.38) than those with previous caring experience (54.87±11.19), a statistically significant difference of 2.47 (95% CI, 0.54 to 4.38), t(533)=2.52, p=.012. Emotional intelligence scores were not associated with performance. Social connection scores for those withdrawing (mean rank=249) and those remaining (mean rank=304.75) were statistically significantly different, U=15,300, z=-2.61, p$_amp_$lt;0.009. Previous caring experience led to worse performance in this cohort. Emotional intelligence was not a useful indicator of performance. Lower scores on the social connection factor were associated

  8. Patients previously treated for nonfunctioning pituitary macroadenomas have disturbed sleep characteristics, circadian movement rhythm, and subjective sleep quality.

    Science.gov (United States)

    Biermasz, N R; Joustra, S D; Donga, E; Pereira, A M; van Duinen, N; van Dijk, M; van der Klaauw, A A; Corssmit, E P M; Lammers, G J; van Kralingen, K W; van Dijk, J G; Romijn, J A

    2011-05-01

    Fatigue and excessive sleepiness have been reported after treatment of nonfunctioning pituitary macroadenomas (NFMA). Because these complaints may be caused by disturbed nocturnal sleep, we evaluated objective sleep characteristics in patients treated for NFMA. We conducted a controlled cross-sectional study. We studied 17 patients (8 women; mean age, 54 yr) in remission of NFMA during long-term follow-up (8 yr; range, 1-18 yr) after surgery (n = 17) and additional radiotherapy (n = 5) without comorbidity except for hypopituitarism and 17 controls matched for age, gender, and body mass index. Sleep was assessed by nocturnal polysomnography, sleep and diurnal movement patterns by actigraphy, and quality of life and subjective sleep characteristics by questionnaires. Compared to controls, patients had reduced sleep efficiency, less rapid eye movement sleep, more N1 sleep, and more awakenings in the absence of excessive apnea or periodic limb movements. Actigraphy revealed a longer sleep duration and profound disturbances in diurnal movement patterns, with more awakenings at night and less activity during the day. Patients scored higher on fatigue and reported impaired quality of life. Patients previously treated for NFMA suffer from decreased subjective sleep quality, disturbed distribution of sleep stages, and disturbed circadian movement rhythm. These observations indicate that altered sleep characteristics may be a factor contributing to impaired quality of life and increased fatigue in patients treated for NFMA.

  9. Cementless total hip arthroplasty for patients previously treated with femoral osteotomy for hip dysplasia: the incidence of periprosthetic fracture

    National Research Council Canada - National Science Library

    Ohishi, Masanobu; Nakashima, Yasuharu; Yamamoto, Takuaki; Motomura, Goro; Fukushi, Jun-ichi; Hamai, Satoshi; Kohno, Yusuke; Iwamoto, Yukihide

    2016-01-01

    Femur deformities can make stem fixation difficult in total hip arthroplasty (THA). We report the clinical results of cementless THA using a press-fit stem in patients who had previously undergone femoral osteotomy for hip...

  10. Final report on the key comparison, CCM.P-K15 in the pressure range from 1.0 × 10-4 Pa to 1.0 Pa.

    Science.gov (United States)

    Wuethrich, Christian; Arai, Kenta; Bergoglio, Mercede; Fedchak, James A; Jousten, Karl; Hong, Seung Soo; Guzman, Jorge Torres

    2017-01-01

    The comparison CCM.P-K15 is a key comparison in pressure involving six laboratories in three regional metrological organizations (RMO). The measurand of the comparison is the accommodation coefficient of two spinning rotating gauge characterized in nitrogen from 0.1 mPa up to 1.0 Pa. The two transfer standards were circulated from November 2009 until March 2011. The circulation consisted of three loops, one for each RMO, and a new calibration by the pilot between each loop. The stability of one of the transfer standards was poor and was worse than expected based on the previous history of the transfer standard while the other transfer standard demonstrated good stability while circulated in Europe and America and a fair stability while circulated in Asia. All the participants demonstrated equivalence to the definition of pressure in their respective primary standards.

  11. Final report on the key comparison, CCM.P-K15 in the pressure range from 1.0 × 10−4 Pa to 1.0 Pa

    Science.gov (United States)

    Wuethrich, Christian; Arai, Kenta; Bergoglio, Mercede; Fedchak, James A.; Jousten, Karl; Hong, Seung Soo; Guzman, Jorge Torres

    2017-01-01

    The comparison CCM.P-K15 is a key comparison in pressure involving six laboratories in three regional metrological organizations (RMO). The measurand of the comparison is the accommodation coefficient of two spinning rotating gauge characterized in nitrogen from 0.1 mPa up to 1.0 Pa. The two transfer standards were circulated from November 2009 until March 2011. The circulation consisted of three loops, one for each RMO, and a new calibration by the pilot between each loop. The stability of one of the transfer standards was poor and was worse than expected based on the previous history of the transfer standard while the other transfer standard demonstrated good stability while circulated in Europe and America and a fair stability while circulated in Asia. All the participants demonstrated equivalence to the definition of pressure in their respective primary standards. PMID:28736459

  12. Biochemical effectiveness of allopurinol and allopurinol-probenecid in previously benzbromarone-treated gout patients.

    Science.gov (United States)

    Reinders, Mattheus K; van Roon, Eric N; Houtman, Pieternella M; Brouwers, Jacobus R B J; Jansen, Tim L Th A

    2007-09-01

    In 2003, the uricosuric drug benzbromarone was withdrawn from the market. The first alternative drug of choice was the xanthine oxidase inhibitor allopurinol. The purpose was to (1) investigate the efficacy of allopurinol (standard dosage) compared with previous treatment with benzbromarone; and (2) investigate the combination therapy allopurinol-probenecid as an effective alternative treatment compared with previous benzbromarone treatment. A prospective, open study was carried out in a cohort of 51 gout patients who discontinued benzbromarone therapy because of market withdrawal. Patients were given 200-300 mg allopurinol (stage 1). When allopurinol failed to attain the target serum urate (sUr) levels probenecid 1,000 mg/day was added (stage 2). Treatment with benzbromarone monotherapy (range: 100-200 mg/day; mean 138 mg/day) resulted in 92% of patients reaching target levels sUr probenecid combination therapy, which resulted in 86% of patients attaining target sUr levels (after failure on allopurinol monotherapy), which was comparable to previous treatment with benzbromarone (p = 0.81). Decrease in sUr levels was 53[9]% (CI 95%: 48-58%), which was a non-significant difference compared to previous treatment with benzbromarone (p = 0.23). Benzbromarone is a very effective antihyperuricemic drug with 91% success in attainment of target sUr levels probenecid proves to be an effective treatment strategy for attaining sUr target levels (86% success).

  13. Rational Design of a New Trypanosoma rangeli Trans-Sialidase for Efficient Sialylation of Glycans

    DEFF Research Database (Denmark)

    Jers, Carsten; Michalak, Malwina; Larsen, Dorte Møller

    2014-01-01

    This paper reports rational engineering of Trypanosoma rangeli sialidase to develop an effective enzyme for a potentially important type of reactivity: production of sialylated prebiotic glycans. The Trypanosoma cruzi trans-sialidase and the homologous T. rangeli sialidase has previously been used...... to investigate the structural requirements for trans-sialidase activity. We observed that the T. cruzi trans-sialidase has a seven-amino-acid motif (197–203) at the border of the substrate binding cleft. The motif differs substantially in chemical properties and substitution probability from the homologous...

  14. Vulnerability factors for disaster-induced child post-traumatic stress disorder: the case for low family resilience and previous mental illness.

    Science.gov (United States)

    McDermott, Brett M; Cobham, Vanessa E; Berry, Helen; Stallman, Helen M

    2010-04-01

    The aim of the present study was to investigate whether parent report of family resilience predicted children's disaster-induced post-traumatic stress disorder (PTSD) and general emotional symptoms, independent of a broad range of variables including event-related factors, previous child mental illness and social connectedness. A total of 568 children (mean age = 10.2 years, SD = 1.3) who attended public primary schools, were screened 3 months after Cyclone Larry devastated the Innisfail region of North Queensland. Measures included parent report on the Family Resilience Measure and Strengths and Difficulties Questionnaire (SDQ)-emotional subscale and child report on the PTSD Reaction Index, measures of event exposure and social connectedness. Sixty-four students (11.3%) were in the severe-very severe PTSD category and 53 families (28.6%) scored in the poor family resilience range. A lower family resilience score was associated with child emotional problems on the SDQ and longer duration of previous child mental health difficulties, but not disaster-induced child PTSD or child threat perception on either bivariate analysis, or as a main or moderator variable on multivariate analysis (main effect: adjusted odds ratio (OR(adj)) = 0.57, 95% confidence interval (CI) = 0.13-2.44). Similarly, previous mental illness was not a significant predictor of child PTSD in the multivariate model (OR(adj) = 0.75, 95%CI = 0.16-3.61). In this post-disaster sample children with existing mental health problems and those of low-resilience families were not at elevated risk of PTSD. The possibility that the aetiological model of disaster-induced child PTSD may differ from usual child and adolescent conceptualizations is discussed.

  15. 75 FR 66009 - Airworthiness Directives; Cessna Aircraft Company (Type Certificate Previously Held by Columbia...

    Science.gov (United States)

    2010-10-27

    ... Company (Type Certificate Previously Held by Columbia Aircraft Manufacturing (Previously the Lancair... directive (AD): Cessna Aircraft Company (Type Certificate Previously Held by Columbia Aircraft Manufacturing... Company (type certificate previously held by Columbia Aircraft Manufacturing (previously The Lancair...

  16. Enthalpy measurement of coal-derived liquids. Technical progress report, August-January 1982. [Isobars of 517. 1, 689. 5, 1034. 2, 1379. 1, and 10342. 5 kPa temperature range of 340 to 664/sup 0/K

    Energy Technology Data Exchange (ETDEWEB)

    Kidnay, A.J.; Yesavage, V.F.

    1982-04-01

    The compound quinoline is discussed. Process flow in the flow calorimeter, operational problems, and equipment modifications are described. Procedural modifications, including a new sample purification procedure, are described. Quinoline enthalpy data are presented along the isobars of 517.1, 689.5, 1034.2, 1379.0, 3799.1, and 10342.5 kPa over a temperature range of 340 to 664/sup 0/K. Experimental enthalpy values and thermodynamic properties derived from this data are compared to corresponding values found in the literature, and to values predicted using computer aided calculations involving three correlations. The three correlations are: the SRK equation of state, and two modifications of the BWR equation of state by Kesler et al. and Starling, respectively. In general, the correlations do not accurately predict the thermodynamic behavior of quinoline. However, the experimental data compare well with available literature data for quinoline vapor pressures.

  17. Drug metabolism and genetic polymorphism in subjects with previous halothane hepatitis

    DEFF Research Database (Denmark)

    Ranek, L; Dalhoff, K; Poulsen, H E

    1993-01-01

    To test the hypothesis that halothane hepatitis is caused by a combination of altered drug metabolism and an immunoallergic disposition, the metabolism of antipyrine, metronidazole, sparteine, phenytoin, and racemic R- and S-mephenytoin was investigated in seven subjects with previous halothane...... hepatitis. The HLA tissue types and the complement C3 phenotypes were also determined. The metabolism of antipyrine and metronidazole was within normal range in all subjects, and they were all fast or extensive metabolizers of sparteine, mephenytoin, and phenytoin. HLA tissue types were unremarkable. Five...

  18. The contribution of previous episodes of pain, pain intensity, physical impairment, and pain-related fear to disability in patients with chronic mechanical neck pain.

    Science.gov (United States)

    Saavedra-Hernández, Manuel; Castro-Sánchez, Adelaida M; Cuesta-Vargas, Antonio I; Cleland, Joshua A; Fernández-de-las-Peñas, César; Arroyo-Morales, Manuel

    2012-12-01

    The influence of physical and psychosocial variables on self-rated disability in patients with chronic mechanical neck pain has not been fully determined. This study examined the relationship of pain, physical impairment, and pain-related fear to disability in individuals with chronic mechanical neck pain. A cross-sectional study was conducted. Ninety-seven (n = 97) subjects (28 men, 69 women; mean age, 39.3 yrs) with chronic mechanical neck pain were prospectively recruited. Demographic information, duration of pain symptoms, pain intensity, pain-related fear, and cervical range of motion were collected on all subjects. Self-reported disability was measured with the Neck Disability Index. Correlation and regression analyses were performed to determine the association among the variables and to determine the proportions of explained variance in disability. Significant positive correlations existed between disability and previous history of neck pain (r = 0.45; P pain intensity (r = 0.32, P = 0.01), and disability and kinesiophobia (r = 0.23, P = 0.02). In addition, a significant negative correlation existed between disability and cervical extension range of motion (r = -0.18, P = 0.04). Stepwise regression analyses revealed that previous neck pain episodes, intensity of neck pain, kinesiophobia, and cervical extension range of motion were significant predictors of disability (r = 0.400; r adjusted = 0.372; F = 14.64; P neck pain, pain intensity, pain-related fear, and cervical extension range of motion explained 37.2% of the variability of self-report disability. Future longitudinal studies will help to determine the clinical implications of these findings.

  19. High Precision Ranging and Range-Rate Measurements over Free-Space-Laser Communication Link

    Science.gov (United States)

    Yang, Guangning; Lu, Wei; Krainak, Michael; Sun, Xiaoli

    2016-01-01

    We present a high-precision ranging and range-rate measurement system via an optical-ranging or combined ranging-communication link. A complete bench-top optical communication system was built. It included a ground terminal and a space terminal. Ranging and range rate tests were conducted in two configurations. In the communication configuration with 622 data rate, we achieved a two-way range-rate error of 2 microns/s, or a modified Allan deviation of 9 x 10 (exp -15) with 10 second averaging time. Ranging and range-rate as a function of Bit Error Rate of the communication link is reported. They are not sensitive to the link error rate. In the single-frequency amplitude modulation mode, we report a two-way range rate error of 0.8 microns/s, or a modified Allan deviation of 2.6 x 10 (exp -15) with 10 second averaging time. We identified the major noise sources in the current system as the transmitter modulation injected noise and receiver electronics generated noise. A new improved system will be constructed to further improve the system performance for both operating modes.

  20. Natural course of sensitization to hen's egg in children not previously exposed to egg ingestion.

    Science.gov (United States)

    de Boissieu, D; Dupont, C

    2006-04-01

    Clinical adverse reactions to egg may occur in infants or children who have never eaten egg. They may be sensitized or even react at first egg ingestion. Few studies are available concerning the reality of egg white allergy in such sensitized children, the natural evolution of this condition and the appropriate decisions to make. To analyze the actuality and natural course of egg allergy in children sensitized without previous of hen's egg ingestion. We set up a clinical decision tree based on clinical history and specific egg white IgE to manage patients who had never ingested egg but were sensitized as demonstrated by a positive SPT and report a cohort of 30 such children The mean level of egg white specific IgE at first analysis, i.e. before 12 months, was high, 28.3 KU(A) /L, with a large range, from 0.6 to >100 KU(A) /L, below 6 KU(A) /L in only 8 patients. In 6 children ("no challenge" group), IgE values remained >8 KU(A) /L by the end of the survey and the oral challenge with egg was always denied. Their mean + SD IgE level was at 51.7 + 38 KU(A) /L at 1 year and 19.7 + 13 KU(A) /L at a mean age of 34 + 5 months. All had an associated anaphylactic reaction with milk and 5 were still allergic to milk by the end of the survey. In the remaining 24 infants, egg was given for the first time at a mean age of 30 + 9 months, by error in 4 cases, all exhibiting an immediate reaction, and in a hospital setting in 20, among whom 14 reacted. Among those 18, with a specific IgE level at 9.1 + 10 KU(A) /L at 28 + 9 months, 4 became tolerant between 3 and 4 years, with specific IgE levels below 1.3 KU(A) /L and a 5th one with specific IgE >100 KU(A) /L at 6 months tolerated scrambled eggs at age 7 year, with specific IgE at 2.6 KU(A) /L. In the 6 others, labeled "non allergic", egg white specific IgE levels were significantly lower, whatever the age, than in the "no challenge" group. The age at challenge was 35 + 8 months, with a mean specific IgE level at 1.0 + 0.9 KU