WorldWideScience

Sample records for random na send

  1. Impact of sending email reminders of the legal requirement for posting results on ClinicalTrials.gov: cohort embedded pragmatic randomized controlled trial.

    Science.gov (United States)

    Maruani, Annabel; Boutron, Isabelle; Baron, Gabriel; Ravaud, Philippe

    2014-09-19

    To evaluate the impact of sending an email to responsible parties of completed trials that do not comply with the Food and Drug Administration Amendments Act 801 legislation, to remind them of the legal requirement to post results. Cohort embedded pragmatic randomized controlled trial. Trials registered on ClinicalTrials.gov. 190 out of 379 trials randomly selected by computer generated randomization list to receive the intervention (personalized emails structured as a survey and sent by one of us to responsible parties of the trials, indirectly reminding them of the legal requirement and potential penalties for non-compliance). The primary outcome was the proportion of results posted on ClinicalTrials.gov at three months. The secondary outcome was the proportion posted at six months. In a second step, two assessors blinded to the intervention group collected the date of the first results being received on ClinicalTrials.gov. A post hoc sensitivity analysis excluding trials wrongly included was performed. Among 379 trials included, 190 were randomized to receive the email intervention. The rate of posting of results did not differ at three months between trials with or without the intervention: 36/190 (19%) v 24/189 (13%), respectively (relative risk 1.5, 95% confidence interval 0.9 to 2.4, P=0.096) but did at six months: 46/190 (24%) v 27/189 (14%), 1.7, 1.1 to 2.6, P=0.014. In the sensitivity analysis, which excluded 48/379 trials (13%), 26/190 (14%) and 22/189 (12%), respectively, results were significant at three months (relative risk 5.1, 1.1 to 22.9, P=0.02) and at six months (4.1, 1.3 to 10.6, P=0.001). Sending email reminders about the FDA's legal requirement to post results at ClinicalTrials.gov improved significantly the posting rate at six months but not at three months.Trial registration ClinicalTrials.gov NCT01658254. © Maruani et al 2014.

  2. Sending Money Like Sending E-mails: Cryptoaddresses, The Universal Decentralised Identities

    Directory of Open Access Journals (Sweden)

    Michal Zima

    2016-12-01

    Full Text Available Sending money in cryptocurrencies is majorly based on public keys or their hashed forms—"addresses." These long random-looking strings are user unfriendly for transferring by other means than via copy-and-paste or QR codes. Replacing such strings with identifiers chosen by users themselves would significantly improve usability of cryptocurrencies. Such identifiers could be memorable, easier to write on paper or to dictate over phone. Main challenge lies in designing a practically usable decentralised system for providing these identifiers. Former solutions have been built as centralised systems or come with nonnegligible limitations. Our solution is reminiscent of a prevalent e-mail system, which is an already user friendly and desirably decentralised system. It is shown that our approach is directly applicable also to other systems that use long cryptographic identifiers.

  3. Sending Scholarship Students Abroad in Ottoman Empire

    Science.gov (United States)

    Kulaç, Onur; Özgür, Hüseyin

    2017-01-01

    The implementation of sending scholarship students abroad that started in the 19th century by Sultan Selim III in Ottoman Empire continued during the period of other Sultans became a significant reference point for the abroad scholarship policy of Turkey. The students that were firstly sent abroad especially for military training, were sent to…

  4. Hochauflösende CT-Densitometrie

    Directory of Open Access Journals (Sweden)

    Patsch J

    2013-01-01

    Full Text Available Die hochauflösende periphere quantitative Computertomographie (HR-pQCT ist eine nicht-invasive Bildgebungstechnik, die in der klinischen und translationellen Knochenforschung zum Einsatz kommt. Neben der getrennten Quantifizierung von kortikaler und trabekulärer Knochenmineraldichte können auch Mikrostrukturparameter und Knochengeometrie volumetrisch erfasst werden. Dichtemessungen erscheinen stabiler gegenüber leichten Bewegungsartefakten als Strukturbestimmungen, was für die Planung von longitudinalen Studien wichtig sein kann.

  5. Sending Nudes: Sex, Self-Rated Mate Value, and Trait Machiavellianism Predict Sending Unsolicited Explicit Images

    Directory of Open Access Journals (Sweden)

    Evita March

    2017-12-01

    Full Text Available Modern dating platforms have given rise to new dating and sexual behaviors. In the current study, we examine predictors of sending unsolicited explicit images, a particularly underexplored online sexual behavior. The aim of the current study was to explore the utility of dark personality traits (i.e., narcissism, Machiavellianism, psychopathy, and sadism and self-rated mate value in predicting attitudes toward and behavior of sending unsolicited explicit images. Two hundred and forty participants (72% female; Mage = 25.96, SD = 9.79 completed an online questionnaire which included a measure of self-rated mate value, a measure of dark personality traits, and questions regarding sending unsolicited explicit images (operationalized as the explicit image scale. Men, compared to women, were found to have higher explicit image scale scores, and both self-rated mate value and trait Machiavellianism were positive predictors of explicit image scale scores. Interestingly, there were no significant interactions between sex and these variables. Further, Machiavellianism mediated all relationships between other dark traits and explicit image scale scores, indicating this behavior is best explained by the personality trait associated with behavioral strategies. In sum, these results provide support for the premise that sending unsolicited explicit images may be a tactic of a short-term mating strategy; however, future research should further explore this claim.

  6. How far can one send a photon?

    Science.gov (United States)

    Gisin, Nicolas

    2015-10-01

    The answer to the question How far can one send a photon? depends heavily on what one means by a photon and on what one intends to do with that photon. For direct quantum communication, the limit is approximately 500 km. For terrestrial quantum communication, near-future technologies based on quantum teleportation and quantum memories will soon enable quantum repeaters that will turn the development of a world-wide-quantum-web (WWQW) into a highly non-trivial engineering problem. For Device-Independent Quantum Information Processing, near-future qubit amplifiers (i.e., probabilistic heralded amplification of the probability amplitude of the presence of photonic qubits) will soon allow demonstrations over a few tens of kilometers.

  7. Special Quasirandom Structures to Study the (K0.5Na0.5)NbO3 Random Alloy

    Science.gov (United States)

    2014-07-31

    and Na on the perovskite A-site. Using these structures, local variations in Na-O interactions are suggested to be the driving force behind the R3c to...structure patterns derived from the random distribution of K and Na on the perovskite A-site. Using these structures, local variations in Na-O...representing the physical properties of the ABO3 perovskite compounds PZT [14] and BaTiO3-SrTiO3 [15,16]. Unfortunately, these approaches require extensive

  8. Sensing the sending of SMS messages: an automated test.

    Science.gov (United States)

    Sheldrake, Rupert; Avraamides, Leonidas; Novák, Matous

    2009-01-01

    The aim of this study was to carry out automated experiments to test for telepathy in connection with text messages. Subjects, aged from 11 to 72, registered online with the names and mobile telephone numbers of three senders. A computer selected a sender at random and asked him/her to send a short message service (SMS) message to the subject via the computer. The computer then asked the subject to guess the sender's name and delivered the message after receiving the guess. A test consisted of nine trials. The effects of subjects' sex and age and the effects of delay on guesses were evaluated. The main outcome measure was the proportion of correct guesses of the sender's name, compared with the 33.3% mean chance expectation. In 886 trials, there were 336 hits (37.9%), significantly above the 33.3% chance level (P = .001). The hit rate in incomplete tests was 38.4% (P = .03), showing that optional stopping could not explain the positive results. Most tests were unsupervised, which left open the possibility of cheating, but high-scoring subjects were retested under filmed conditions, where no cheating was detected, with 19 hits in 43 trials (44.2%; P = 0.09).

  9. Die posisie van die Helper in die sending

    Directory of Open Access Journals (Sweden)

    I. J. van der Walt

    1972-06-01

    Full Text Available Gedurende die aanvangsjare van die sending het die helper ’n onmisbare funksie vervul. Hulle het die onherbergsame binnelande geken, waardevolle kontakpunte vir die sendelinge geopen en hulle mense geestelik help voorlig en voorberei.

  10. DIE EINDE VAN SENDING Fases in die Sendingbedryf

    African Journals Online (AJOL)

    questions are focused on the situation in the mission work of the Dutch ..... opmerkings gemaak wat relevant is vir ons argument. ... onafhanklik sou funksioneer (“self support”), en self met die verdere sending ... (“the euthanasia of mission”).

  11. Die posisie van die Helper in die sending

    Directory of Open Access Journals (Sweden)

    I. J. van der Walt

    1972-05-01

    Full Text Available Gedurende die aanvangsjare van die sending het die helper ’n onmisbare funksie vervul. Hulle het die onherbergsame binnelande geken, waardevolle kontakpunte vir die sendelinge geopen en hulle mense geestelik help voorlig en voorberei.

  12. The Role of Altruism in Sending and Spending Remittances

    Directory of Open Access Journals (Sweden)

    Akira Shimada

    2011-06-01

    Full Text Available We investigate the effects of altruism on migrants' decisions to send money home and on their households' decisions to invest or to consume those remittances. Previous studies have devoted extensive attention to migrants' altruism toward recipients and little to recipients'altruism toward migrants. We find that the migrant sends larger remittances home when he feels more altruistic toward other household members, while he may send nothing if he feels less altruistic. We also find that other household members in the home country likely consume rather than invest remittances if they are highly altruistic toward the migrant. Our results may partially explain why countries receiving large remittances do not always make large investments, and suggest that altruism among household members does not necessarily enhance a country's development and growth through remittances.

  13. [The labor migration sending regions in the state of Zacatecas].

    Science.gov (United States)

    Tamayo, J; Lozano Ascencio, F

    1991-01-01

    "In a preliminary survey in the state of Zacatecas, [Mexico,] we identified those municipalities which contribute most to the migration of Mexican workers to the United States; later, we corroborated our findings in situ and drew up an approximation of the geographic and economic characteristics of those municipalities, which make up 'migration sending zones or regions' in the state." (SUMMARY IN ENG) excerpt

  14. Strong Laws of Large Numbers for Arrays of Rowwise NA and LNQD Random Variables

    Directory of Open Access Journals (Sweden)

    Jiangfeng Wang

    2011-01-01

    Full Text Available Some strong laws of large numbers and strong convergence properties for arrays of rowwise negatively associated and linearly negative quadrant dependent random variables are obtained. The results obtained not only generalize the result of Hu and Taylor to negatively associated and linearly negative quadrant dependent random variables, but also improve it.

  15. Cloud Instrument Powered by Solar Cell Sends Data to Pachube

    OpenAIRE

    Doru Ursutiu; Silviu Folea; Marius Ghercioiu

    2010-01-01

    Despite the economic downturn, there have been quite a few new developments in the world of remote measurements lately. Tag4M (www.tag4m.com) introduced the concept of cloud instrument where sensors connected to WiFi tags send data to off-the-shelf Access Points which are part of the WiFi infrastructure that exists in enterprises, retail outlets, factories, and warehouses. Access Points route the data to the Internet where specialized web applications receive the information for processing an...

  16. Hospitals will send an integrated nurse home with each discharge.

    Science.gov (United States)

    Morrow, Thomas

    2015-01-01

    Hospitals must adapt to the rapidly changing environment of risk by changing the health behavior of their population. There is only one way to do this efficiently and at scale; send a nurse home with every patient at the time of discharge. That nurse can ensure adherence to medication and slowly, over time, transform personal behavior to evidence based levels ... basically taking their medication as prescribed, changing eating habits, increasing exercise, getting people to throw away their cigarettes, teaching them how to cope, improving their sleep and reducing their stress. But, this approach will require a nurse to basically "live" with the patient for prolonged periods of time, as bad health behaviors are quick to start but slow to change or end. The rapid developments in artificial intelligence and natural language understanding paired with cloud based computing and integrated with a variety of data sources has led to a new marketplace comprised of cognitive technologies that can emulate even the most creative, knowledgeable and effective nurse. Termed the Virtual Health Assistant, your patients can literally talk to these agents using normal conversational language. The possibility to send a nurse home with each patient to maintain adherence and prevent readmissions has arrived. The technology is available. Who will step forward to reap the rewards first?

  17. Send and Receive fax documents using electronic mail

    CERN Multimedia

    2005-01-01

    Any CERN Staff Member can now send and receive faxes directly through email using the new fax service. To do so, you need to register and obtain your “personal” fax number using the page http://cern.ch/fax. Once you have your fax number, you can fax someone by sending an email message to the address of the form name@number.mail2fax.cern.ch, for example: Joe.Bloggs@000441719999999.mail2fax.cern.ch In the example, “000441719999999” is the fax number to call, as seen from inside CERN, in this case, in London. “Joe.Bloggs” is the name of your correspondent and it will appear on the cover page along with your name, email address, your “personal” fax number, and the subject of the email. Documentation and additional examples of fax addresses are on http://cern.ch/fax The eventual text of your email will be transmitted in the fax, followed by the optional attachments, as extra pages. Attachments can be in Acrobat (.pdf), Text (.txt), Word (.doc) , Excel (.xls) or Powerpoint (.ppt) formats. Once ...

  18. Send and Receive fax documents using electronic mail

    CERN Multimedia

    2005-01-01

    Any CERN Staff Member can now send and receive faxes directly through email using the new fax service. To do so, you need to register and obtain your “personal” fax number using the page http://cern.ch/fax. Once you have your fax number, you can fax someone by sending an email message to the address of the form name@number.mail2fax.cern.ch, for example: Joe.Bloggs@000441719999999.mail2fax.cern.ch In the example, “000441719999999” is the fax number to call, as seen from inside CERN, in this case, in London. “Joe.Bloggs” is the name of your correspondent and it will appear on the cover page along with your name, email address, your “personal” fax number, and the subject of the email. Documentation and additional examples of fax addresses are on http://cern.ch/fax The eventual text of your email will be transmitted in the fax, followed by the optional attachments, as extra pages. Attachments can be in Acrobat (.pdf), Text (.txt), Word (.doc) , Excel (.xls) or Powerpoint (.ppt) formats. Once the ...

  19. Ideologies of nationhood in sending-state transnationalism: comparing Surinam and Turkey

    NARCIS (Netherlands)

    Mügge, L.

    2013-01-01

    Why do some sending states encourage continued emigrant involvement whereas others do not? And to what extent does sending-state transnationalism lead to a redefinition of borders? Although research on sending-state transnationalism is flourishing, so far it only covers the positive cases and

  20. Send your data into the cloud and make it… vaporize

    CERN Multimedia

    Computer Security Team

    2011-01-01

    “Cloud computing” --- the term is as nebulous as real clouds.   Basically, it means storing data somewhere on the Internet. This certainly has advantages, since this data will be available anytime from anywhere. For example, the Google mailbox is available from everywhere; “Dropbox” provides a central storage for any type of files; “ZAPR” and “TeamViewer”, once installed, allow you to share your local files by just sending around links, or give third parties full remote access to your PC, respectively. In addition, there is a growing number of cloud synchronisation services (e.g. “iCloud”/”MobileMe”, “Firefox Sync”, “Dropbox”) which provide (semi-)automatic back-ups of all local files of a laptop, PC or mobile phone. But hold on. What actually is transferred into the cloud? Personal files like bank statements? Passwords, especially CE...

  1. Sending Safety Video over WiMAX in Vehicle Communications

    Directory of Open Access Journals (Sweden)

    Jun Steed Huang

    2013-10-01

    Full Text Available This paper reports on the design of an OPNET simulation platform to test the performance of sending real-time safety video over VANET (Vehicular Adhoc NETwork using the WiMAX technology. To provide a more realistic environment for streaming real-time video, a video model was created based on the study of video traffic traces captured from a realistic vehicular camera, and different design considerations were taken into account. A practical controller over real-time streaming protocol is implemented to control data traffic congestion for future road safety development. Our driving video model was then integrated with the WiMAX OPNET model along with a mobility model based on real road maps. Using this simulation platform, different mobility cases have been studied and the performance evaluated in terms of end-to-end delay, jitter and visual experience.

  2. Generic Model to Send Secure Alerts for Utility Companies

    Directory of Open Access Journals (Sweden)

    Perez–Díaz J.A.

    2010-04-01

    Full Text Available In some industries such as logistics services, bank services, and others, the use of automated systems that deliver critical business information anytime and anywhere play an important role in the decision making process. This paper introduces a "Generic model to send secure alerts and notifications", which operates as a middleware between enterprise data sources and its mobile users. This model uses Short Message Service (SMS as its main mobile messaging technology, however is open to use new types of messaging technologies. Our model is interoperable with existing information systems, it can store any kind of information about alerts or notifications at different levels of granularity, it offers different types of notifications (as analert when critical business problems occur,asanotificationina periodical basis or as 2 way query. Notification rules can be customized by final users according to their preferences. The model provides a security framework in the cases where information requires confidentiality, it is extensible to existing and new messaging technologies (like e–mail, MMS, etc. It is a platform, mobile operator and hardware independent. Currently, our solution is being used at the Comisión Federal de Electricidad (Mexico's utility company to deliver secure alerts related to critical events registered in the main power generation plants of our country.

  3. Independent Validation of the SEND-PD and Correlation with the MDS-UPDRS Part IA

    OpenAIRE

    Mayela Rodríguez-Violante; Amin Cervantes-Arriaga; Salvador Velázquez-Osuna; Rodrigo Llorens-Arenas; Humberto Calderón-Fajardo; Dan Piña-Fuentes; Pablo Martinez-Martin

    2014-01-01

    Introduction. Neuropsychiatric symptoms in Parkinson's disease can be assessed by the MDS-UPDRS part IA. The Scale for Evaluation of Neuropsychiatric Disorders in Parkinson's disease (SEND-PD) has been recently developed to assess the severity of some neuropsychiatric symptoms. The objective of this study is to compare the performance of the SEND-PD with the corresponding items of the MDS-UPDRS part IA. Methods. Patients with Parkinson's disease were evaluated using the MDS-UPDRS and the SEND...

  4. EXPECTATIONS OF PARENTS WHO ARE SENDING THEIR CHILDREN TO SWIMMING SPORTS

    OpenAIRE

    Hüseyin Öztürk; Ahmet Yılgın; Fatih Armutcu

    2017-01-01

    This study was designed to investigate the causes of families' sending their children to swimming summer schools. The working group constitutes the parents who send their children to the summer school swimming schools in Kahramanmaras. A total of 203 people, 155 female and 48 male, participated in the research. In order to determine the reasons for sending the children to the swimming schools, the scale developed by Meral (2010) was utilized. While the findings obtained in the study were eval...

  5. 29 CFR 4000.28 - What if I send a computer disk?

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false What if I send a computer disk? 4000.28 Section 4000.28... I send a computer disk? (a) In general. We determine your filing or issuance date for a computer... paragraph (b) of this section. (1) Filings. For computer-disk filings, we may treat your submission as...

  6. Sending family history questionnaires to patients before a colonoscopy improves genetic counseling for hereditary colorectal cancer

    NARCIS (Netherlands)

    Kessels, K.; Eisinger, J.D.; Letteboer, T.G.; Offerhaus, G.J.; Siersema, P.D.; Moons, L.M.

    2017-01-01

    OBJECTIVES: To investigate whether sending a family history questionnaire to patients prior to undergoing colonoscopy results in an increased availability of family history and better genetic counseling. METHODS: A questionnaire was mailed to patients before they underwent outpatient colonoscopy at

  7. Sending family history questionnaires to patients before a colonoscopy improves genetic counseling for hereditary colorectal cancer

    NARCIS (Netherlands)

    Kessels, Koen; Eisinger, Joey D; Letteboer, Tom G|info:eu-repo/dai/nl/304815837; Offerhaus, G Johan A; Siersema, Peter D|info:eu-repo/dai/nl/110603826; Moons, Leon M G

    OBJECTIVES: To investigate whether sending a family history questionnaire to patients prior to undergoing colonoscopy results in an increased availability of family history and better genetic counseling. METHODS: A questionnaire was mailed to patients before they underwent outpatient colonoscopy at

  8. Independent Validation of the SEND-PD and Correlation with the MDS-UPDRS Part IA

    Directory of Open Access Journals (Sweden)

    Mayela Rodríguez-Violante

    2014-01-01

    Full Text Available Introduction. Neuropsychiatric symptoms in Parkinson’s disease can be assessed by the MDS-UPDRS part IA. The Scale for Evaluation of Neuropsychiatric Disorders in Parkinson’s disease (SEND-PD has been recently developed to assess the severity of some neuropsychiatric symptoms. The objective of this study is to compare the performance of the SEND-PD with the corresponding items of the MDS-UPDRS part IA. Methods. Patients with Parkinson’s disease were evaluated using the MDS-UPDRS and the SEND-PD by independent raters. Partial SEND-PD and neuropsychiatric MDS-UPDRS part IA were constructed with equivalent items for comparison. Results. A total of 260 consecutive patients were included. Overall, 61.2% of the patients did not report any psychotic symptom and 83.5% did not report any ICD symptom. On the other hand, 78.5% of the patients did report at least one symptom related to apathy, depression, or anxiety. The partial SEND-PD score was 2.9±3.1 (range from 0 to 16. The neuropsychiatric MDS-UPDRS part IA score was 2.9±3 (range from 0 to 14. The correlation coefficient between corresponding items ranged from 0.67 to 0.98 and between both summary indexes was rs=0.93 (all, P<0.001. Conclusion. A high association between equivalent items of the SEND-PD and the MDS-UPDRS was found.

  9. Making sense of SEND; the Standard for Exchange of Nonclinical Data.

    Science.gov (United States)

    Briggs, Katharine

    2017-12-01

    The Standard for Exchange of Nonclinical Data (SEND) is currently the preferred submission format for nonclinical animal data by the US FDA and became a requirement on the 18th December 2016. Application of these data standards is the first step to being able to perform cross-study querying and is expected to open up opportunities for data mining and meta-analysis by the pharmaceutical industry. This paper reports on our experiences in developing a tool to allow recent SEND formatted studies to be explored alongside historical nonclinical data already gathered as part of the eTOX project. Combining SEND data with historical data will positively impact the power of any analysis performed and increase the likelihood of being able to detect rare effects. It describes the use of KNIME in generating dose group averages and incidences from individual animal level data captured in SEND. There are a number of options for opening and reading SEND files but the benefits of using KNIME are that it is a free, open source data mining framework which allows the data to be viewed in a holistic manner rather than one domain at a time. Additionally it incorporates several nodes useful for aggregating and visualising the data to more easily identify patterns and trends. Copyright © 2017 Elsevier Inc. All rights reserved.

  10. Effect of Moringa oleifera Leaf Capsules on Glycemic Control in Therapy-Naïve Type 2 Diabetes Patients: A Randomized Placebo Controlled Study

    Directory of Open Access Journals (Sweden)

    Rutchaporn Taweerutchana

    2017-01-01

    Full Text Available Background. Studies showed effects of Moringa oleifera (MO on lowering blood sugar levels in animal and diabetes patients. The aims of this study were to determine the effect of MO leaf capsules on glucose control in therapy-naïve type 2 diabetes mellitus (T2DM and to evaluate its safety. Method. This was a prospective randomized placebo controlled study. Therapy-naïve T2DM was randomly assigned to receive either 8 grams per day of MO leaf capsules (MO leaf group or placebo for 4 weeks. Clinical and laboratory characteristics were recorded at screening and at the end of 4-week study. 9-point plasma glucose was obtained before and every week during the study. Results. Thirty-two T2DM patients were enrolled. The mean age was 55 years and the mean HbA1C was 7.0%. There was no significant difference in FPG and HbA1C between groups. MO leaf group had SBP reduction by 5 mmHg as compared to baseline but this difference had no statistical significance. There were no adverse effects of MO leaf. Conclusions. Moringa oleifera leaf had no effect on glycemic control and no adverse effects in T2DM. Interestingly, this study demonstrated that MO leaf had a tendency on blood pressure reduction in T2DM, and this result needs further investigation.

  11. SENDS criteria from the diversification of MAST procedures. Implementation of preoperative simulation; SENDS-Kriterien als Entwicklungstheorem der MAST-Prozeduren. Einfuehrung praeoperativer Simulation

    Energy Technology Data Exchange (ETDEWEB)

    Rieger, B. [Universitaetsklinikum Carl Gustav Carus, Klinik und Poliklinik fuer Neurochirurgie, Dresden (Germany)

    2015-10-15

    Minimal access spinal technologies (MAST) lead to a diversification of surgical procedures, which requires careful selection of the procedure and outcome monitoring. For a rational selection of the procedure simulation, endoscopy, navigation, decompression and stabilization (SENDS) criteria can be derived from the development of the MAST procedures. Preoperative simulation has diagnostic and therapeutic values. The SENDS criteria can be verified indirectly via outcome control. Biomechanically meaningful diagnostic x-rays of the spinal segment to be surgically treated are currently carried out with the patient in inclination and reclination. Software-related preoperative simulation based on these x-ray images facilitates the selection and implementation of the MAST procedure. For preoperative simulation motion shots are needed in inclination, neutral position and reclination and the dimensions can be obtained using an x-ray ball or a computed tomography (CT) scan. The SENDS criteria are useful because established procedures based on these criteria reach a comparable outcome. Preoperative simulation appears to be a useful selection criterion. Preoperatively it is necessary to collate patient and segment information in order to provide each patient with individualized treatment. So far there is no evidence for a better outcome after preoperative simulation but a reduction of surgery time and intraoperative radiation exposure could already be demonstrated. Minimally invasive methods should be preferred if there is a comparable outcome. The establishment of new procedures has to be accompanied by the maintenance of a spine register. Minimally invasive surgical procedures should be individualized for each patient and segment. Mobility X-ray images should be prepared for use with the preoperative simulation as the information content significantly increases with respect to the MAST procedure. (orig.) [German] Die Minimal Access Spine Technology (MAST) fuehrt zur

  12. Effect of NaFeEDTA-Fortified Soy Sauce on Anemia Prevalence in China: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

    Science.gov (United States)

    Huo, Jun Sheng; Yin, Ji Yong; Sun, Jing; Huang, Jian; Lu, Zhen Xin; Regina, Moench-Pfanner; Chen, Jun Shi; Chen, Chun Ming

    2015-11-01

    To assess the effect of sodium iron ethylenediaminetetraacetate (NaFeEDTA)-fortified soy sauce on anemia prevalence in the Chinese population. A systematic review was performed to identify potential studies by searching the electronic databases of PubMed, Cochrane Library, WHO Library, HighWire, CNKI, and other sources. The selection criteria included randomized controlled trials that compared the efficacy of NaFeEDTA-fortified soy sauce with that of non-fortified soy sauce. Anemia rates and hemoglobin levels were the outcomes of interest. Inclusion decisions, quality assessment, and data extraction were performed by two reviewers independently. A total of 16 studies met the inclusion criteria for anemia rate analysis, of which 12 studies met the inclusion criteria for hemoglobin analysis. All included studies assessed the effect of NaFeEDTA-fortified soy sauce on anemia rates and hemoglobin concentrations. After the intervention, the hemoglobin concentration increased and anemia rates decreased significantly as compared with the non-fortified soy sauce groups. For anemia rates, data from 16 studies could be pooled, and the pooled estimate odds ratio was 0.25 (95% CI 0.19-0.35). For hemoglobin concentrations, data from 12 studies could be pooled, and the pooled weighted mean difference was 8.81 g/L (95% CI 5.96-11.67). NaFeEDTA-fortified soy sauce has a positive effect on anemia control and prevention in the at-risk population. Copyright © 2015 The Editorial Board of Biomedical and Environmental Sciences. Published by China CDC. All rights reserved.

  13. 'It sends a message': Liberian opinion leaders' responses to the trial of Charles Taylor

    NARCIS (Netherlands)

    Glasius, M.

    2015-01-01

    This article investigates the potential impact of an international criminal trial on a post-conflict society. It assesses the claims of legal expressivism, which conceptualizes criminal justice as a message sending mechanism that can enunciate societal condemnation of atrocities, establish an

  14. Students with Self-Identified Special Educational Needs and Disabilities (Si-SEND): Flourishing or Languishing!

    Science.gov (United States)

    Skrzypiec, Grace; Askell-Williams, Helen; Slee, Phillip; Rudzinski, Adrian

    2016-01-01

    Students' wellbeing is an essential component of their ability to function well, not only at school but also in all life domains. Many studies have investigated student wellbeing. However, empirical studies about the wellbeing of students with special educational needs and disabilities (SEND) are scarce. Furthermore, many studies have adopted a…

  15. Discovering non-random segregation of sister chromatids: The naïve treatment of a premature discovery

    Directory of Open Access Journals (Sweden)

    Karl G. Lark

    2013-02-01

    Full Text Available The discovery of non-random chromosome segregation is discussed from the perspective of what was known in1965 and1966. The distinction between daughter, parent or grandparent strands of DNA was developed in a bacterial system and led to the discovery that multiple copies of DNA elements of bacteria are not distributed randomly with respect to the age of the template strand. Experiments with higher eukaryotic cells demonstrated that during mitosis Mendel’s laws were violated; and the initial serendipitous choice of eukaryotic cell system led to the striking example of non-random segregation of parent and grand-parent DNA template strands in primary cultures of cells derived from mouse embryos. Attempts to extrapolate these findings to established TC lines demonstrated that the property could be lost. Experiments using plant root tips demonstrated that the phenomenon exists in plants and that it was, at some level, under genetic control. Despite publication in major journals and symposia (Lark et al. (1966a; Lark (1967a; 1967b; 1969, 1969a; 1969b the potential implications of these findings were ignored for several decades. Here we explore possible reasons for the pre-maturity (Stent, 1972 of this discovery.

  16. Explaining Labour Market Inactivity in Migrant-Sending Families: Housework, Hammock, or Higher Education

    OpenAIRE

    Görlich, Dennis; Omar Mahmoud, Toman; Trebesch, Christoph

    2007-01-01

    This article presents a new perspective on the impact of migration and remittances on labour market participation and time allocation in migrant-sending families. Departing from the common finding that labour market participation is lower in migrant households, we investigate whether the reasons for inactivity, i.e. leisure consumption, home production and higher education are affected by migration. Based on household survey data from Moldova, our results challenge the assertion that those wh...

  17. When Germany sends troops abroad: the case for a limited reform of the Parliamentary Participation Act

    OpenAIRE

    Brose, Ekkehard

    2013-01-01

    "The Parliamentary Participation Act has proved to be a valuable tool for ensuring the democratic legitimacy of any decision to send Bundeswehr troops abroad. Since it came into force in 2005, the German Bundestag has given its assent to more than 70 requests of the Federal Government for the deployment of German troops abroad, or the extension of such mandates, and has not rejected a single application. Nevertheless, there is a problem: Germany's partners see participation with military pers...

  18. 13 CFR 134.614 - What deadlines apply to my application for an award and where do I send it?

    Science.gov (United States)

    2010-01-01

    ... application for an award and where do I send it? 134.614 Section 134.614 Business Credit and Assistance SMALL... and where do I send it? After you have prevailed in an administrative proceeding or in a discrete... award for fees and expenses may still be filed, but it will not be considered by the ALJ until a final...

  19. 41 CFR 102-118.195 - What documents must a transportation service provider (TSP) send to receive payment for a...

    Science.gov (United States)

    2010-07-01

    ... transportation service provider (TSP) send to receive payment for a transportation billing? 102-118.195 Section... must a transportation service provider (TSP) send to receive payment for a transportation billing? For shipments bought on a TD, the TSP must submit an original properly certified GBL, PPGBL, or bill of lading...

  20. Sexting among singles in the USA: prevalence of sending, receiving, and sharing sexual messages and images.

    Science.gov (United States)

    Garcia, Justin R; Gesselman, Amanda N; Siliman, Shadia A; Perry, Brea L; Coe, Kathryn; Fisher, Helen E

    2016-07-29

    Background: The transmission of sexual images and messages via mobile phone or other electronic media (sexting) has been associated with a variety of mostly negative social and behavioural consequences. Research on sexting has focussed on youth, with limited data across demographics and with little known about the sharing of private sexual images and messages with third parties. Methods: The present study examines sexting attitudes and behaviours, including sending, receiving, and sharing of sexual messages and images, across gender, age, and sexual orientation. A total of 5805 single adults were included in the study (2830 women; 2975 men), ranging in age from 21 to 75+ years. Results: Overall, 21% of participants reported sending and 28% reported receiving sexually explicit text messages; both sending and receiving 'sexts' was most common among younger respondents. Although 73.2% of participants reported discomfort with unauthorised sharing of sexts beyond the intended recipient, of those who had received sext images, 22.9% reported sharing them with others (on average with 3.17 friends). Participants also reported concern about the potential consequences of sexting on their social lives, careers, and psychosocial wellbeing. Conclusion: Views on the impact of sexting on reputation suggest a contemporary struggle to reconcile digital eroticism with real-world consequences. These findings suggest a need for future research into negotiations of sexting motivations, risks, and rewards.

  1. Methods and participant characteristics of a randomized intervention to promote physical activity and healthy eating among brazilian high school students: the Saude na Boa project.

    Science.gov (United States)

    Nahas, Markus V; de Barros, Mauro V G; de Assis, Maria Alice A; Hallal, Pedro C; Florindo, Alex A; Konrad, Lisandra

    2009-03-01

    A cross-cultural, randomized study was proposed to observe the effects of a school-based intervention designed to promote physical activity and healthy eating among high school students in 2 cities from different regions in Brazil: Recife and Florianopolis. The objective of this article is to describe the methodology and subjects enrolled in the project. Ten schools from each region were matched and randomized into intervention and control conditions. A questionnaire and anthropometry were used to collect data in the first and last month of the 2006 school year. The sample (n=2155 at baseline; 55.7% females; 49.1% in the experimental group) included students 15 to 24 years, attending nighttime classes. The intervention focused on simple environmental/organizational changes, diet and physical activity education, and personnel training. The central aspects of the intervention have been implemented in all 10 intervention schools. Problems during the intervention included teachers' strikes in both sites and lack of involvement of the canteen owners in schools. The Saude na Boa study provides evidence that public high schools in Brazil represent an important environment for health promotion. Its design and simple measurements increase the chances of it being sustained and disseminated to similar schools in Brazil.

  2. Effectiveness of Chinese massage therapy (Tui Na) for chronic low back pain: study protocol for a randomized controlled trial.

    Science.gov (United States)

    Yang, Mingxiao; Feng, Yue; Pei, Hong; Deng, Shufang; Wang, Minyu; Xiao, Xianjun; Zheng, Hui; Lai, Zhenhong; Chen, Jiao; Li, Xiang; He, Xiaoguo; Liang, Fanrong

    2014-10-29

    Low back pain is a common, disabling musculoskeletal disorder in both developing and developed countries. Although often recommended, the potential efficacy of massage therapy in general, and Chinese massage (tuina) in particular, for relief of chronic low back pain (CLBP) has not been fully established due to inadequate sample sizes, low methodological quality, and subclinical dosing regimens of trials to date. Thus, the purpose of this randomized controlled trial (RCT) is to evaluate the comparative effectiveness of tuina massage therapy versus conventional analgesics for CLBP. The present study is a single center, two-arm, open-label RCT. A total of 150 eligible CLBP patients will be randomly assigned to either a tuina treatment group or a conventional drug control group in a 1:1 ratio. Patients in the tuina group receive a 20 minutes, 4-step treatment protocol which includes both structural and relaxation massage, administered in 20 sessions over a period of 4 weeks. Patients in the conventional drug control group are instructed to take a specific daily dose of ibuprofen. The primary outcome measure is the change from baseline back pain and function, measured by Roland-Morris Disability Questionnaire, at two months. Secondary outcome measures include the visual analogue scale, Japanese orthopedic association score (JOAS), and McGill pain questionnaire. The design and methodological rigor of this trial will allow for collection of valuable data to evaluate the efficacy of a specific tuina protocol for treating CLBP. This trial will therefore contribute to providing a solid foundation for clinical treatment of CLBP, as well as future research in massage therapy. This trial was registered with ClinicalTrials.gov of the National Institute of Health on 22 October 2013 (http://NCT01973010).

  3. Ropivacaína, articaína ou combinação de ropivacaína e articaína em anestesia peridural para cesariana: estudo randomizado, prospectivo e duplo-cego Ropivacaína, articaína o la combinación de ropivacaína y articaína en la anestesia epidural para cesárea: estudio aleatorio, prospectivo y doble ciego Ropivacaine, articaine or combination of ropivacaine and articaine for epidural anesthesia in cesarean section: a randomized, prospective, double-blinded study

    Directory of Open Access Journals (Sweden)

    Derya Arslan Yurtlu

    2013-02-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Iniciar a anestesia peridural com anestésicos locais de longa duração consome uma quantidade significativa de tempo, o que pode ser problemático em centros de anestesia obstétrica muito movimentados. Aventamos a hipótese de que uma combinação de articaína e ropivacaína proporcionaria início mais rápido e mesmo uma recuperação precoce das características do bloqueio sensório-motor. MÉTODOS: Sessenta parturientes a termo agendadas para cesariana eletiva foram randomicamente alocadas em três grupos para receber 20 mL de articaína a 2% (Grupo A, 10 mL de articaína a 2% + 10 mL de ropivacaína a 0,75% (Grupo AR ou 20 mL de ropivacaína a 0,75% (Grupo R via cateter peridural. O tempo de início do bloqueio sensorial até T10-T6 e o nível máximo de bloqueio, o tempo para a regressão de dois segmentos do nível máximo de bloqueio sensorial e o tempo de início e duração do bloqueio motor foram todos registrados. A necessidade de analgésicos adicionais, intra- e pós-operatoriamente, também foi registrada. RESULTADOS: Os dados demográficos foram semelhantes. Os tempos de início do bloqueio sensorial até os níveis T10 e T6 foram significativamente menores nos grupos A e AR, em comparação com o Grupo R (p JUSTIFICATIVA Y OBJETIVOS: Iniciar la anestesia epidural con anestésicos locales de larga duración consume una cantidad significativa de tiempo, siendo un problema en los centros de anestesia obstétrica que tienen mucho movimiento. Barajamos la hipótesis de que una combinación de articaína y ropivacaína proporcionaría un inicio más rápido e incluso una rápida recuperación de las características del bloqueo sensitivo motor. MÉTODOS: Sesenta parturientes a término que tenían cita para la cesárea electiva se ubicaron aleatoriamente en tres grupos para recibir 20 mL de articaína al 2% (Grupo A, 10 mL de articaína al 2% + 10 mL de ropivacaína al 0,75% (Grupo AR o 20 mL de ropivacaína

  4. Capsaicin on the viability of random-pattern skin flaps in rats Capsaicina na viabilidade de retalhos isquêmicos randômicos em ratos

    Directory of Open Access Journals (Sweden)

    Gustavo Roberto de Godoy

    2010-10-01

    Full Text Available PURPOSE: To evaluate the effects of capsaicin on the viability of ischemic random-pattern skin flaps in rats. METHODS:Forty EPM1-Wistar rats were randomized into two groups of 20 animals each, the capsaicin group and the control group. A random-pattern skin flap measuring 10 x 4cm was raised and a plastic barrier was placed between the flap and the donor site. After the surgical procedure, the control group was treated with an inert vehicle in the form of a cream applied uniformly to a rayon bandage which, in turn, was applied to the surface of the skin flap. The capsaicin group was treated in the same way, but in this case capsaicin was added to the cream. This procedure was repeated for two consecutive days. RESULTS: There was a significantly smaller amount of flap necrosis in the capsaicin group (35.07% than in the control group (44.75% (p=0.035. CONCLUSION:Topical administration of capsaicin improved the viability of ischemic random-pattern skin flaps in rats.OBJETIVO: Avaliar os efeitos da capsaicina na viabilidade de retalhos isquêmicos randômicos em ratos. MÉTODOS: Quarenta ratos EPM1-Wistar foram distribuídos ao acaso em dois grupos de 20 animais cada, um grupo capsaicina e um grupo controle. Um retalho isquêmico randômico medindo 10 x 4cm foi elevado e uma barreira plástica foi colocada entre o retalho e a área doadora. Após o procedimento cirúrgico, o grupo controle foi tratado com um veículo inerte sob a forma creme aplicado uniformemente sobre uma atadura de rayon, que, por sua vez, foi aplicada à superfície do retalho. O grupo capsaicina foi tratado da mesma forma, porém a capsaicina foi adicionada ao creme. Este procedimento foi repetido por dois dias consecutivos. RESULTADOS: Houve uma quantidade significativamente menor da necrose do retalho no grupo capsaicina (35,07% comparado ao grupo controle (44,75% (p=0,035. CONCLUSÃO: A administração tópica da capsaicina melhorou a viabilidade de retalhos isquêmicos rand

  5. Journal Club: Voice recognition dictation: analysis of report volume and use of the send-to-editor function.

    Science.gov (United States)

    Williams, Dennis R; Kori, Sheila K; Williams, Brenda; Sackrison, Sandra J; Kowalski, Henryk M; McLaughlin, Michael G; Kuszyk, Brian S

    2013-11-01

    The purpose of this study was to evaluate use of the send-to-editor function of a radiology voice recognition dictation system and compare study volumes of radiologists who self-edit with those of radiologists who send reports to the editor. Use of voice recognition shortcuts was also evaluated. Voice recognition dictation systems were installed in a six-hospital system, including an 800-bed tertiary care center and five community hospitals, in 2002. This became the only means of radiologist dictation in July 2005. Report volumes, use of the send-to-editor function, and use of shortcuts were tracked from October 2005 through October 2008. A subspecialty private radiology group, ranging from 37 radiologists in July 2005 to 50 radiologists in October 2008, interpreted the imaging studies. Radiologists had no financial incentives to self-edit. The percentage of radiologists using the send-to-editor function remained relatively constant at 46%, resulting in 21% of total reports sent to the editor. Radiologists who used the send-to-editor function dictated approximately 41% more reports than those who self-edited. The volume of reports generated by general radiologists reading large volumes of computed radiography cases and sending to the editor was greater than that of radiologists who self-edited (p reports than radiologists who did not, suggesting that the send-to-editor function may be useful for improving productivity among radiologists reading large volumes of computed radiography cases.

  6. The Gatekeeper Disparity: Why Do Some Medical Schools Send More Medical Students into Urology?

    Science.gov (United States)

    Kutikov, Alexander; Bonslaver, Jason; Casey, Jessica T.; Degrado, Justin; Dusseault, Beau N.; Fox, Janelle A.; Lashley-Rogers, Desri; Richardson, Ingride; Smaldone, Marc C.; Steinberg, Peter L.; Trivedi, Deep B.; Routh, Jonathan C.

    2010-01-01

    Introduction Urology continues to be a highly desirable specialty, despite decreasing exposure of students to Urology in U.S. medical schools. In this study, we set out to assess how U.S. medical schools compare to one another with regard to the number of students that each sends into Urological training and to evaluate the reasons why some medical schools consistently send more students into urology than others. Materials and Methods The authors obtained AUA Match data for the 5 Match seasons from 2005–2009. A survey of all successful participants was then performed. The survey instrument was designed to determine what aspects of the medical school experience influenced students to choose to specialize in Urology. A bivariate and multivariate analysis was then performed to assess which factors correlated with more students entering Urology from a particular medical school. Results Between 2005 and 2009, 1,149 medical students from 130 medical schools successfully participated in the Urology match. Of the 132 allopathic medical schools, 128 sent at least 1 student into Urology (mean 8.9, median 8, SD 6.5). A handful of medical schools were remarkable outliers, sending significantly more students into Urology than other institutions. Multivariate analysis revealed that a number of medical-school related variables including strong mentorship, medical school ranking, and medical school size correlated with more medical students entering Urology. Conclusion Some medical schools launch more Urologic careers than others. Although reasons for these findings are multifactorial, recruitment of Urologic talent pivots on these realities. PMID:21168862

  7. Effects of Spirulina platensis supplementation on lipid profile in HIV-infected antiretroviral naïve patients in Yaounde-Cameroon: a randomized trial study.

    Science.gov (United States)

    Ngo-Matip, Marthe-Elise; Pieme, Constant Anatole; Azabji-Kenfack, Marcel; Biapa, Prosper Cabral Nya; Germaine, Nkenfack; Heike, Englert; Moukette, Bruno Moukette; Emmanuel, Korosky; Philippe, Stefanini; Mbofung, Carl Moses; Ngogang, Jeanne Yonkeu

    2014-12-13

    Cardiovascular diseases (CVD) and metabolic alterations are among the majors public health concern that have been reported in people living with HIV infections. Factors contributing to cardio metabolic syndrome in HIV include body fat distribution, dyslipidemia, insulin resistance, cardiovascular dysfunction and inflammation. The aim of the study was to determine the effect of Spirulina platensis (Cyanobacteriaceae) supplementation versus local diet on lipid profile in HIV-infected antiretroviral-naive patients. A prospective single-blind, randomized, multicentre study was conducted from February 2010 to December 2012. A total of 320 HIV antiretroviral-naïve patients were screened and 169 were recruited in this study. Patients were randomized and received either Spirulina supplementation combined with local diet (n=82) or local diet only (n=87). Age, weight, body mass index (BMI), lipid profile, CD4 count, and local food intake variables were assessed on three separate occasions (three, six and twelve months). An average age of the patients was 35.6±9 years. The majority of participants were female 67.1%. Regarding the lipid profile, there is a significant increase in HDL-cholesterol and a significant decrease in total cholesterol, LDL-cholesterol and triglycerides in the group of patients who consumed Spirulina platensis. A change in the atherogenic index defined by the ratio CT/HDL-C substitutable by LDL-C/HDL-C and the TC/HDL decreased significantly from 10.83 at baseline to 2.22 after 12 months (p=0.21 and pSpirulina. Nutritional supplementation with Spirulina combined with a quantitative and qualitative balanced diet for at least six months can retard an exposition to lipid abnormalities in HIV-infected antiretroviral-naive patients. Further studies are recommended on a large group of people not infected with HIV and exposed to cardiovascular risk factors.

  8. Vacancy-related diffusion correlation effects in a simple cubic random alloy and on the Na-K sublattice of alkali feldspar

    Science.gov (United States)

    Wilangowski, F.; Stolwijk, N. A.

    2015-07-01

    Motivated by the need to analyse experimental data on ionic conductivity in alkali feldspar, we performed Monte Carlo (MC) simulations of vacancy diffusion in random binary systems. We employed an efficient procedure for the calculation of the vacancy correlation factor ?, which includes the computation of the associated partial correlation factors (PCFs) ? and ?. Test simulations on a simple cubic lattice show the improvements compared to previous MC data and the discrepancies with the Manning model. Vacancy correlation factors on the Na-K sublattice in the monoclinic structure of alkali feldspar proved to be dependent on crystal orientation. For the ?-direction, PCFs related to the four different jump types were calculated. We also examined the percolation behaviour for extreme ratios of the atomic jump frequencies. The results are found to agree with known data for the simple cubic lattice. In the case of feldspar, we provide the first useful estimates for the percolation threshold and the associated critical exponent using a simplified set of jump frequencies.

  9. Predictors of discontinuation of benzodiazepine prescription after sending a letter to long-term benzodiazepine users in family practice.

    NARCIS (Netherlands)

    Gorgels, W.J.M.J.; Oude Voshaar, R.C.; Mol, A.J.J.; Lisdonk, E.H. van de; Balkom, A.J.L.M. van; Breteler, M.H.M.; Hoogen, H.J.M. van den; Mulder, J.; Zitman, F.G.

    2006-01-01

    BACKGROUND: Predictors of benzodiazepine discontinuation after sending a discontinuation letter by the family practitioner have not been established sufficiently. OBJECTIVE: To identify predictors of short- and long-term discontinuation of benzodiazepine use and relapse in use after a minimal

  10. The research and application of the NDP protocol vulnerability attack and the defense technology based on SEND

    Science.gov (United States)

    Xi, Huixing

    2017-05-01

    Neighbor discovery protocol (NDP) is the underlying protocol in the IPv6 protocol, which is mainly used to solve the problem of interconnection between nodes on the same link. But with wide use of IPV6, NDP becomes the main objects of a variety of attacks due to a lack of security mechanism. The paper introduces the working principle of the NDP and methods of how the SEND protocol to enhance NDP security defense. It also analyzes and summarizes the security threats caused by the defects of the protocol itself. On the basis of the SEND protocol, the NDP data packet structure is modified to enhance the security of the SEND. An improved NDP cheating defense technology is put forward to make up the defects of the SEND protocol which can't verify the correctness of the public key and cannot bind the MAC address.

  11. A Study of Relationship between "Effective Listening" and "Understanding and Sending Messages" with Conflict Management among Managers in Ardabil Elementary Schools

    Directory of Open Access Journals (Sweden)

    Shahin Taghavinejad-Namin

    2015-08-01

    Full Text Available Background and objectives : This study has been accomplished with the aim of investigating the relationship between managers' communication skills and conflict management in elementary schools in the city of Ardabil. Material and Methods: This is a cross-sectional study. The statistical population consisted of 150 elementary school principals in Ardabil. 106 participants were selected by using Krejcie-Morgan table randomly and through stratified sampling method. Data were collected through Jerabek communication skills questionnaire and Robbins conflict management questionnaire. Questionnaire’s face validity was reviewed and confirmed by the experts. Their reliability coefficient was (0.82 for communication skills and (0.95 for conflict management by using Cronbach's alpha. Data were analyzed using analytical and descriptive statistical methods (Pearson correlation coefficient test, single-sample t-test, and multiple regression. Results: Results showed that there are positive and significant relationship between communication skills (effective listening, understanding and sending messages, regulating emotions, insight into learning process, and decisiveness in communication and conflict management strategies(denial of opposition, control, solution orientation. Conclusion: Communication skills such as effective listening can be a good predictor for solving conflicts in conflict management but understanding and sending messages cannot predict conflict management abilities of managers. ​

  12. NA-NET numerical analysis net

    Energy Technology Data Exchange (ETDEWEB)

    Dongarra, J. [Tennessee Univ., Knoxville, TN (United States). Dept. of Computer Science]|[Oak Ridge National Lab., TN (United States); Rosener, B. [Tennessee Univ., Knoxville, TN (United States). Dept. of Computer Science

    1991-12-01

    This report describes a facility called NA-NET created to allow numerical analysts (na) an easy method of communicating with one another. The main advantage of the NA-NET is uniformity of addressing. All mail is addressed to the Internet host ``na-net.ornl.gov`` at Oak Ridge National Laboratory. Hence, members of the NA-NET do not need to remember complicated addresses or even where a member is currently located. As long as moving members change their e-mail address in the NA-NET everything works smoothly. The NA-NET system is currently located at Oak Ridge National Laboratory. It is running on the same machine that serves netlib. Netlib is a separate facility that distributes mathematical software via electronic mail. For more information on netlib consult, or send the one-line message ``send index`` to netlib{at}ornl.gov. The following report describes the current NA-NET system from both a user`s perspective and from an implementation perspective. Currently, there are over 2100 members in the NA-NET. An average of 110 mail messages pass through this facility daily.

  13. NA-NET numerical analysis net

    Energy Technology Data Exchange (ETDEWEB)

    Dongarra, J. (Tennessee Univ., Knoxville, TN (United States). Dept. of Computer Science Oak Ridge National Lab., TN (United States)); Rosener, B. (Tennessee Univ., Knoxville, TN (United States). Dept. of Computer Science)

    1991-12-01

    This report describes a facility called NA-NET created to allow numerical analysts (na) an easy method of communicating with one another. The main advantage of the NA-NET is uniformity of addressing. All mail is addressed to the Internet host na-net.ornl.gov'' at Oak Ridge National Laboratory. Hence, members of the NA-NET do not need to remember complicated addresses or even where a member is currently located. As long as moving members change their e-mail address in the NA-NET everything works smoothly. The NA-NET system is currently located at Oak Ridge National Laboratory. It is running on the same machine that serves netlib. Netlib is a separate facility that distributes mathematical software via electronic mail. For more information on netlib consult, or send the one-line message send index'' to netlib{at}ornl.gov. The following report describes the current NA-NET system from both a user's perspective and from an implementation perspective. Currently, there are over 2100 members in the NA-NET. An average of 110 mail messages pass through this facility daily.

  14. Do false positive alerts in naïve clinical decision support system lead to false adoption by physicians? A randomized controlled trial.

    Science.gov (United States)

    Tsai, Chung-You; Wang, Shi-Heng; Hsu, Min-Huei; Li, Yu-Chuan Jack

    2016-08-01

    False positive alerts in patient-safety-related clinical decision support systems (CDSS) are defined as alerts which incorrectly prompt when no-risk patients are encountered. It is an unfavorable condition which may potentially mislead physicians. The aim is to investigate physician responses toward false positive (FP) and true positive (TP) alerts in CDSS for the prevention of contrast-induced nephropathy (CIN). A two-arm cluster randomized controlled trial was conducted in university hospitals. Eligible physicians were randomized to receive alert intervention or no intervention (groups 1 and 2, respectively). The alert system was embedded with a deliberately non-specific risk detection tool in order to generate TP and FP alerts. The naïve alert system would alert the physician to cancel the order regardless of the patient being at-risk or not at-risk. CIN risk was stratified as at-risk and no-risk according to a patient's pre-existing renal function. Contrast imaging order-cancellation rate was measured as primary outcome. 3802 contrast-enhanced examination orders from 66 physicians were analyzed. Demographic data and risk distributions of patients were similar and well-balanced between two groups. In the intervention group, a total of 1892 alerts were generated (332 TP alerts and 1560 FP alerts). Order-cancellation rates were 5.1% versus 1.4% in groups 1 and 2 for at-risk patients (relative risk [RR] = 3.69) from TP alerts, and 1.0% versus 1.4% for no-risk patients (RR = 0.71) from FP alerts. Using generalized linear model with generalized estimating equation, the FP alerts had no order-cancellation effect when compared to the control arm (adjusted RR = 0.69; 95%CI, 0.36-1.32). The TP alerts had a larger order-cancellation effect than that of the control arm (adjusted RR = 2.95; 95%CI, 0.94-9.27), which revealed a marginal trend toward significance. However, the effect was not statistically significant (adjusted RR = 1.24; 95%CI, 0

  15. Migration and Sexuality: A Comparison of Mexicans in Sending and Receiving Communities.

    Science.gov (United States)

    Parrado, Emilio A; Flippen, Chenoa A

    2010-03-01

    The reconstruction of sexuality after migration is a central dimension of immigrant health and an integral part of the process of adaptation and incorporation. Despite its significance there is little quantitative information measuring the changes in sexual behavior accompanying migration. This paper contributes to the literature connecting immigrant adaptation and health risks by comparing sexual practices and attitudes among Mexicans in Durham, NC and Mexican sending communities. Consistent with a social constructivist approach to sexuality we show that compared to non-migrants, Mexicans residing in the U.S. exhibit heightened exposure to risk, including casual and, among men, commercial partners. The enhanced risks associated with migration vary systematically by gender and marital status and are accompanied by variation in attitudes towards sexuality, with the U.S. context associated with higher tolerance for infidelity and biological explanations of sexuality. We discuss the implications for immigrant adaptation and health policies in the U.S. and abroad.

  16. Sequence based prediction of DNA-binding proteins based on hybrid feature selection using random forest and Gaussian naïve Bayes.

    Directory of Open Access Journals (Sweden)

    Wangchao Lou

    Full Text Available Developing an efficient method for determination of the DNA-binding proteins, due to their vital roles in gene regulation, is becoming highly desired since it would be invaluable to advance our understanding of protein functions. In this study, we proposed a new method for the prediction of the DNA-binding proteins, by performing the feature rank using random forest and the wrapper-based feature selection using forward best-first search strategy. The features comprise information from primary sequence, predicted secondary structure, predicted relative solvent accessibility, and position specific scoring matrix. The proposed method, called DBPPred, used Gaussian naïve Bayes as the underlying classifier since it outperformed five other classifiers, including decision tree, logistic regression, k-nearest neighbor, support vector machine with polynomial kernel, and support vector machine with radial basis function. As a result, the proposed DBPPred yields the highest average accuracy of 0.791 and average MCC of 0.583 according to the five-fold cross validation with ten runs on the training benchmark dataset PDB594. Subsequently, blind tests on the independent dataset PDB186 by the proposed model trained on the entire PDB594 dataset and by other five existing methods (including iDNA-Prot, DNA-Prot, DNAbinder, DNABIND and DBD-Threader were performed, resulting in that the proposed DBPPred yielded the highest accuracy of 0.769, MCC of 0.538, and AUC of 0.790. The independent tests performed by the proposed DBPPred on completely a large non-DNA binding protein dataset and two RNA binding protein datasets also showed improved or comparable quality when compared with the relevant prediction methods. Moreover, we observed that majority of the selected features by the proposed method are statistically significantly different between the mean feature values of the DNA-binding and the non DNA-binding proteins. All of the experimental results indicate that

  17. Domestic horses send signals to humans when they face with an unsolvable task.

    Science.gov (United States)

    Ringhofer, Monamie; Yamamoto, Shinya

    2017-05-01

    Some domestic animals are thought to be skilled at social communication with humans due to the process of domestication. Horses, being in close relationship with humans, similar to dogs, might be skilled at communication with humans. Previous studies have indicated that they are sensitive to bodily signals and the attentional state of humans; however, there are few studies that investigate communication with humans and responses to the knowledge state of humans. Our first question was whether and how horses send signals to their potentially helpful but ignorant caretakers in a problem-solving situation where a food item was hidden in a bucket that was accessible only to the caretakers. We then examined whether horses alter their behaviours on the basis of the caretakers' knowledge of where the food was hidden. We found that horses communicated to their caretakers using visual and tactile signals. The signalling behaviour of the horses significantly increased in conditions where the caretakers had not seen the hiding of the food. These results suggest that horses alter their communicative behaviour towards humans in accordance with humans' knowledge state.

  18. Discovery Monday - 'The hunt for the phantom particles: sending neutrinos through the Alps'

    CERN Multimedia

    2004-01-01

    Work on the decay tube for the CERN Neutrinos to Gran Sasso (CNGS) Project. Each second, billions of neutrinos bombard every square centimetre of the Earth's surface and therefore pass through our bodies, without us realising it. These phantom particles only rarely interact with matter. They provide physicists with much food for thought, as they are difficult to 'catch' in detectors. Neutrinos are all the more elusive as they are capable of metamorphosis. There are in fact three types of neutrino, the electron neutrino, the muon neutrino and the tau neutrino, and each can mutate into the other. In 2006 CERN will send a beam of muon neutrinos through the Earth's crust to the Gran Sasso National Laboratory (Italy) some 730 kilometres away, in order to better understand the metamorphoses which the neutrino undergoes. At the next Discovery Monday, light will be shed on the path that these intriguing particles will take to Gran Sasso. You will also learn about the methods physicists use to try and catch them in or...

  19. 40 CFR 1054.250 - What records must I keep and what reports must I send to EPA?

    Science.gov (United States)

    2010-07-01

    ... ENGINES AND EQUIPMENT Certifying Emission Families § 1054.250 What records must I keep and what reports... model year, you must send us a report describing information about engines you produced during the model year as follows: (1) State the total production volume for each engine family that is not subject to...

  20. 41 CFR 102-118.260 - Must my agency send all quotations, tenders, or contracts with a TSP to GSA?

    Science.gov (United States)

    2010-07-01

    ... quotations, tenders, or contracts with a TSP to GSA? 102-118.260 Section 102-118.260 Public Contracts and..., Tenders Or Contracts § 102-118.260 Must my agency send all quotations, tenders, or contracts with a TSP to... submitted with the tender: (1) Issuing TSP, Bureau, Agency or Conference. (2) Tender number. (3) Standard...

  1. The importance of role sending in the sensemaking of change agent roles.

    Science.gov (United States)

    Tucker, Danielle A; Hendy, Jane; Barlow, James

    2015-01-01

    The purpose of this paper is to investigate what happens when a lack of role-sending results in ambiguous change agent roles during a large scale organisational reconfiguration. The authors consider the role of sensemaking in resolving role ambiguity of middle manager change agents and the consequences of this for organisational restructuring. Data were collected from a case study analysis of significant organisational reconfiguration across a local National Health Service Trust in the UK. Data consists of 82 interviews, complemented by analysis of over 100 documents and field notes from 51 hours of observations collected over five phases covering a three year period before, during and after the reconfiguration. An inductive qualitative analysis revealed the sensemaking processes by which ambiguity in role definition was resolved. The data explains how change agents collectively make sense of a role in their own way, drawing on their own experiences and views as well as cues from other organisational members. The authors also identified the organisational outcomes which resulted from this freedom in sensemaking. This study demonstrates that by leaving too much flexibility in the definition of the role, agents developed their own sensemaking which was subsequently very difficult to manipulate. In creating new roles, management first needs to have a realistic vision of the task and roles that their agents will perform, and second, to communicate these expectations to both those responsible for recruiting these roles and to the agents themselves. Much of the focus in sensemaking research has been on the importance of change agents' sensemaking of the change but there has been little focus on how change agents sensemake their own role in the change.

  2. Childbearing among first- and second-generation Russians in Estonia against the background of the sending and host countries

    Directory of Open Access Journals (Sweden)

    Allan Puur

    2017-04-01

    Full Text Available Background: An expanding literature documents the childbearing patterns of migrants and their descendants in contemporary Europe. The existing evidence pertains mainly to the northern, western, and southern regions of the continent, while less is known about the fertility of migrants who have moved between the countries of Eastern Europe. Objective: The aim of this study is to examine the fertility patterns of first- and second-generation Russians in Estonia, relative to the sending and host populations. Methods: The study draws on the Estonian and Russian Generations and Gender Surveys. Proportional hazards models are estimated for the transitions to first, second, and third births. Results: Russian migrants in Estonia exhibit greater similarity to the sending population, with a lower propensity for having a second and third birth than the host population. This pattern extends to the descendants of migrants. However, mixed Estonian-Russian parentage, enrolment in Estonian-language schools, and residence among the host population are associated with the convergence of Russians' childbearing behaviour with the host-country patterns. The findings support the cultural maintenance and adaptation perspectives; selectivity was found to be less important. Contribution: The study focuses on a previously under-researched context and underscores the importance of contextual factors in shaping migrants' fertility patterns. It raises the possibility that, depending on the childbearing trends and levels among the sending and receiving populations, large-scale migration may reduce rather than increase aggregate fertility in the host country. With the advancement of the fertility transition in sending countries, this situation may become more common in Europe in the future.

  3. A randomized, open-label, multicenter study evaluating the efficacy of peginterferon alfa-2a versus interferon alfa-2a, in combination with ribavirin, in naïve and relapsed chronic hepatitis C patients.

    Science.gov (United States)

    Nevens, F; Van Vlierberghe, H; D'Heygere, E; Delwaide, J; Adler, M; Henrion, J; Lenaerts, A; Hendlisz, A; Michielsen, P; Bastens, B; Brenard, R; Laureys, A

    2010-01-01

    A large multicenter trial to compare the efficacy of peginterferon alfa-2a with interferon alfa-2a, in combination with ribavirin, in chronic hepatitis C patients. Efficacy data for prior relapsers are reported because treatment recommendations for this patient population are not well defined. This study was a multicenter, prospective, randomized clinical trial. The primary efficacy endpoint was sustained virologic response in naive patients (n = 348) and relapsers (n = 95). Sustained virologic response rates were similar in naïve patients and relapsers, both for non-pegylated and pegylated interferon (respectively 27 and 26% and 54 and 43%). Pegylated interferon given for 48 weeks did not improved the relapse rate: 15.9 and 27.3% for non-pegylated and 16.7 and 30.4% for pegylated interferon, naïve vs relapsers respectively. Stepwise logistic regression analysis revealed a significant association between slow response (detectable HCV RNA at week 12 and undetectable at week 24) and relapse in patients with an end-of-treatment response (55% versus 13% respectively; p = 0.02; odds ratio = 6.07). This trial confirms the value of using peginterferon alfa-2a in both naïve and relapsed patients and provides support for a more tailored approach to treatment for relapsers and particulary for patients with a slow viral response.

  4. Executing scatter operation to parallel computer nodes by repeatedly broadcasting content of send buffer partition corresponding to each node upon bitwise OR operation

    Science.gov (United States)

    Archer, Charles J [Rochester, MN; Ratterman, Joseph D [Rochester, MN

    2009-11-06

    Executing a scatter operation on a parallel computer includes: configuring a send buffer on a logical root, the send buffer having positions, each position corresponding to a ranked node in an operational group of compute nodes and for storing contents scattered to that ranked node; and repeatedly for each position in the send buffer: broadcasting, by the logical root to each of the other compute nodes on a global combining network, the contents of the current position of the send buffer using a bitwise OR operation, determining, by each compute node, whether the current position in the send buffer corresponds with the rank of that compute node, if the current position corresponds with the rank, receiving the contents and storing the contents in a reception buffer of that compute node, and if the current position does not correspond with the rank, discarding the contents.

  5. Immunological and virological changes in antiretroviral naïve human immunodeficiency virus infected patients randomized to G-CSF or placebo simultaneously with initiation of HAART

    DEFF Research Database (Denmark)

    Aladdin, H; Ullum, H; Katzenstein, T

    2000-01-01

    To determine the efficacy of combined G-CSF and highly active antiretroviral treatment (HAART), a randomized, double blind, placebo controlled study was conducted. Treatment naive human immunodeficiency virus (HIV) infected patients were randomized to receive either placebo or G-CSF (0.3 mg/ml, 3...... and CD8+ naive and memory T cells increased in response to HAART, and there was a trend towards more pronounced increases in several T-cell subpopulations in the G-CSF group. The CD56+ NK cells increased significantly more in the G-CSF group compared with placebo (P = 0. 000). All patients in the G...

  6. Alternative Therapy for Patients With Obstructive Sleep Apnea/Hypopnea Syndrome: A 1-year, Single-blind, Randomized Trial of Tui Na.

    Science.gov (United States)

    Lu, Cheng-Nan; Friedman, Michael; Lin, Hsin-Ching; Bi, Kuo-Wei; Hsueh, Tun-Pin; Chang, Hsueh-Wen; Su, Mao-Chang; Lin, Meng-Chih

    2017-07-01

    Context • Obstructive sleep apnea/hypopnea syndrome (OSAHS) is among the most prevalent of sleep-related breathing disorders. No long-term follow-up studies have documented the continued success of lifestyle changes in treatment; oral appliances have an approximate 50% success rate; compliance with continuous positive airway pressure is poor, ranging from 50% to 89%; and the success rate of upper-airway surgery is only 66.4%. Therefore, some OSAHS patients seek alternative treatments. Objectives • The study intended to examine the efficacy of traditional Chinese therapeutic massage (tui na) for patients with OSAHS. Design • The research team designed a prospective study. Setting • The study took place at the outpatient clinic of the sleep center at the Kaohsiung Chang Gung Memorial Hospital (Kaohsiung, Taiwan), an academic tertiary medical center. Participants • Participants were 31 patients with moderate to severe OSAHS. Intervention • Each participant received a tui na treatment at multiple acupoints 2 ×/wk for 10 wk for approximately 15 min/session. Outcome Measures • At baseline and 3 mo after treatment, participants completed subjective measures, including (1) quality of life using a 36-item, short-form health survey (SF-36); (2) subjective snoring intensity indicated by bed-partners using a 0-10 visual analog scale (VAS); and (3) excessive daytime sleepiness (EDS) status, using a Chinese version of the Epworth Sleepiness Scale (CESS). The research team completed objective measures, including (1) polysomnography, (2) body mass index, and (3) neck circumference. Results • Twenty patients completed the full course of treatment. The apnea/hypopnea index per hour decreased from 43.8 ± 26.9 to 37.8 ± 31.7 after the treatments, with P = .049 (paired t test). The arousal index and rapid eye movement stage of sleep improved significantly. Statistically significant improvements were observed for the SF-36 on the score for the physical component

  7. Did send-down experience benefit youth? A reevaluation of the social consequences of forced urban-rural migration during China's Cultural Revolution.

    Science.gov (United States)

    Xie, Yu; Jiang, Yang; Greenman, Emily

    2008-06-01

    During China's Cultural Revolution, a large proportion of urban youth were forced to go to the countryside as a result of the state's "send-down" policy. Past research has been ambivalent about the long-term social consequences for the Chinese youth who experienced send-down. Some scholars have suggested that the send-down experience may have yielded beneficial effects. To test this claim, we analyze data from the Survey of Family Life in Urban China, which we conducted in three large cities in 1999. Questions available in this data set allow us to ascertain the send-down experience of both the respondent and a sibling and educational attainment at the times of send-down and return. Our analyses of the new data show that the send-down experience does not seem to have benefited the affected Chinese youth. Differences in social outcomes between those who experienced send-down and those who did not are either non-existent or spurious due to other social processes.

  8. A Phase 2 Randomized, Double-Blind, Multicenter Trial of Imexon Plus Gemcitabine Versus Gemcitabine Plus Placebo in Patients With Metastatic Chemotherapy-naïve Pancreatic Adenocarcinoma.

    Science.gov (United States)

    Cohen, Steven J; Zalupski, Mark M; Conkling, Paul; Nugent, Francis; Ma, Wen Wee; Modiano, Manuel; Pascual, Rolan; Lee, Fa Chyi; Wong, Lucas; Hersh, Evan

    2015-12-24

    Imexon is a cyanoaziridine-derived iminopyrrolidone which has synergistic cytotoxicity with gemcitabine. A phase 1 study of the combination demonstrated good tolerance with encouraging clinical activity and thus we conducted this randomized phase II study. Patients with measurable, metastatic, treatment-naive pancreatic adenocarcinoma were randomized 1:1 to receive gemcitabine at 1000 mg/m days 1, 8, and 15 with either imexon, 875 mg/m or placebo days 1, 8, and 15 every 28 days. The primary endpoint was overall survival. Secondary endpoints included progression-free survival and response rate. A total of 142 patients were randomized, 72 to the imexon containing arm and 70 to the placebo arm. Patients in the imexon arm received an average of 3.6 cycles (range, 1 to 23) compared with 4.4 (range, 1 to 21) in the placebo arm. There was no increased rate of ≥grade 3 toxicity in the imexon arm. Seven patients had objective responses in the imexon arm (13.7%), whereas 9 did in the placebo arm (17%). In the imexon arm, 23 patients had ≥50% reduction in CA 19-9 from baseline (33%), whereas 22 did in the placebo arm (31.4%). The median progression-free survival was 2.8 months in the imexon arm (95% confidence interval [CI], 2.0-4.1 m) and 3.8 months in the placebo arm (95% CI, 2.2-4.7 m), P=0.504. The median overall survival time in the imexon arm was 5.2 months (95% CI, 4.2-6.7 m) as compared with 6.8 m (95% CI, 4.9-8.5 m) in the placebo arm, P=0.6822. The combination of imexon and gemcitabine does not result in improved outcome as initial therapy of metastatic pancreatic adenocarcinoma.

  9. Hand preference for sending mobile-phone text messages: associations with sex, writing hand, and throwing hand.

    Science.gov (United States)

    Lambert, Anthony; Hallett, Charlene

    2009-07-01

    Hand preference for sending mobile-phone text messages ("texting") and its relationship with hand preference for other activities were investigated in a questionnaire study with 886 participants. Overall rates of both sinistrality and dextrality were reduced for texting, in comparison with other activities, due to the substantial number of individuals who use both hands simultaneously when performing this activity. Because they both involve verbal expression, it was hypothesised that the association between hand preferences for texting and writing might be stronger than the association between either of these tasks and more spatial activities, such as throwing. This prediction was not confirmed, either in the sample as a whole or in a sub-group of individuals who reported writing and throwing with opposite hands. Females were less likely than males to use their left hand when sending text messages. Implications of these findings are discussed, in relation to theoretical views of handedness and in relation to practical aspects of mobile-phone design.

  10. Accuracy of send-out test ordering: a College of American Pathologists Q-Probes study of ordering accuracy in 97 clinical laboratories

    National Research Council Canada - National Science Library

    Valenstein, Paul N; Walsh, Molly K; Stankovic, Ana K

    2008-01-01

    .... Representatives from 97 clinical laboratories provided information about the processes they use to send tests to reference facilities and their order entry and specimen routing error rates. In aggregate, 98...

  11. Micronutrient deficiency and treatment adherence in a randomized controlled trial of micronutrient supplementation in ART-naïve persons with HIV.

    Directory of Open Access Journals (Sweden)

    Louise Balfour

    Full Text Available The MAINTAIN study is an on-going RCT comparing high-dose micronutrient and anti-oxidant supplementation versus recommended daily allowance (RDA vitamins in slowing HIV immune deficiency progression in ART-naïve people with HIV infection.We planned analysis of the first 127 participants to determine the baseline prevalence of serum micronutrient deficiencies and correlates, as well as tolerance and adherence to study interventions.Participants receive eight capsules twice daily of 1 high-dose or 2 RDA supplements for two years and are followed-up quarterly for measures of immune deficiency progression, safety and tolerability. Regression analysis was used to identify correlates of micronutrient levels at baseline. Adherence was measured by residual pill count, self-report using the General Treatment Scale (GTS and short-term recall HIV Adherence Treatment Scale (HATS.Prior micronutrient supplementation (within 30 days was 27% at screening and 10% of study population, and was not correlated with baseline micronutrient levels. Low levels were frequent for carotene (24%80% in 75% of participants.Micronutrient levels in asymptomatic HIV+ persons are in keeping with population norms, but micronutrient deficiencies are frequent. Adherence levels are high, and will permit a valid evaluation of treatment effects.ClinicalTrials.gov NCT00798772.

  12. Evaluation of the Effectiveness of a Psychoeducational Intervention in Treatment-Naïve Patients with Antidepressant Medication in Primary Care: A Randomized Controlled Trial

    Directory of Open Access Journals (Sweden)

    R. Casañas

    2015-01-01

    Full Text Available Background. There is evidence supporting the effectiveness of psychoeducation (PE in patients with symptoms of depression in primary care (PC, but very few studies have assessed this intervention in antidepressant-naïve patients. The aim of this study is to assess the effectiveness of a PE program in these patients, since the use of antidepressant (AD medication may interfere with the effects of the intervention. Methods. 106 participants were included, 50 from the PE program (12 weekly 1.5-hour sessions and 56 from the control group (CG that received the usual care. Patients were assessed at baseline and at 3, 6, and 9 months. The main outcome measures were the Beck Depression Inventory (BDI and remission based on the BDI. The analysis was carried out on an intention-to-treat basis. Results. The PE program group showed remission of symptoms of 40% (P=0.001 posttreatment and 42% (P=0.012 at 6 months. The analysis only showed significant differences in the BDI score posttreatment (P=0.008; effect size Cohen’s d′=0.55. Conclusions. The PE intervention is an effective treatment in the depressive population not treated with AD medication. Before taking an AD, psychoeducational intervention should be considered.

  13. Evaluation of the Effectiveness of a Psychoeducational Intervention in Treatment-Naïve Patients with Antidepressant Medication in Primary Care: A Randomized Controlled Trial

    Science.gov (United States)

    Casañas, R.; Catalán, R.; Penadés, R.; Real, J.; Valero, S.; Muñoz, MA.; Lalucat-Jo, LL.; Casas, M.

    2015-01-01

    Background. There is evidence supporting the effectiveness of psychoeducation (PE) in patients with symptoms of depression in primary care (PC), but very few studies have assessed this intervention in antidepressant-naïve patients. The aim of this study is to assess the effectiveness of a PE program in these patients, since the use of antidepressant (AD) medication may interfere with the effects of the intervention. Methods. 106 participants were included, 50 from the PE program (12 weekly 1.5-hour sessions) and 56 from the control group (CG) that received the usual care. Patients were assessed at baseline and at 3, 6, and 9 months. The main outcome measures were the Beck Depression Inventory (BDI) and remission based on the BDI. The analysis was carried out on an intention-to-treat basis. Results. The PE program group showed remission of symptoms of 40% (P = 0.001) posttreatment and 42% (P = 0.012) at 6 months. The analysis only showed significant differences in the BDI score posttreatment (P = 0.008; effect size Cohen's d′ = 0.55). Conclusions. The PE intervention is an effective treatment in the depressive population not treated with AD medication. Before taking an AD, psychoeducational intervention should be considered. PMID:26380366

  14. Live-attenuated Tetravalent Dengue Vaccine in Dengue-naïve Children, Adolescents, and Adults in Mexico City: Randomized Controlled Phase 1 Trial of Safety and Immunogenicity.

    Science.gov (United States)

    Poo, Jorge; Galan, Francisco; Forrat, Remi; Zambrano, Betzana; Lang, Jean; Dayan, Gustavo

    2011-01-01

    Preliminary results in healthy, young US adults showed that a tetravalent, live-attenuated dengue vaccine (TDV) was safe and immunogenic, but no data are available in children. In a multicenter, randomized, controlled, observer-blinded study in the city of Mexico, children aged 2 to 5, 6 to 11, and 12 to 17 years (36 children per age group), and adults (n = 18) aged dengue serotype was in the range 77% to 92%, compared with 85% to 94% after completion of the YF-TDV-TDV regimen. Of the 2- to 11-year-old participants, 95% were seropositive against ≥3 serotypes after 3 vaccinations. A 3-dose TDV regimen had a favorable safety profile in children and adults and elicited neutralizing antibody responses against all 4 serotypes. These findings support the continued development of this vaccine.

  15. Assessing Short-term Deterioration in Maintenance-naïve Patients with COPD Receiving Umeclidinium/Vilanterol and Tiotropium: A Pooled Analysis of Three Randomized Trials.

    Science.gov (United States)

    Maleki-Yazdi, M Reza; Singh, Dave; Anzueto, Antonio; Tombs, Lee; Fahy, William A; Naya, Ian

    2017-01-01

    Dual bronchodilator therapy is reserved as a second-line treatment in patients with chronic obstructive pulmonary disease (COPD) and provides benefits in lung function and health status versus monotherapy. The aim of this study was to determine whether early initiation of a dual bronchodilator versus monotherapy reduced the risk of deterioration in COPD. This post hoc pooled analysis investigated the efficacy and safety of umeclidinium/vilanterol (UMEC/VI) 62.5/25 mcg/day compared with tiotropium (TIO) 18 mcg/day in a maintenance-naïve (MN) subgroup of patients relative to the intent-to-treat (ITT) population from three 6-month active comparator studies (n = 1747). Other treatment arms (UMEC/VI 125/25, VI 25 and UMEC 125) comprised 850 patients in total but were not included in this analysis. The primary endpoint was trough forced expiratory volume in 1 s (FEV 1 ). St George's Respiratory Questionnaire (SGRQ) score, rescue medication use, and a novel composite endpoint of short-term clinically important deterioration (CID; ≥100 ml decrease in trough FEV 1 , ≥4-unit increase in SGRQ score, or a COPD exacerbation) were also assessed. UMEC/VI improved trough FEV 1 versus TIO at day 169 [least squares mean (95% confidence interval): MN: 146 ml (102-189) and ITT: 95 ml (71-118); both P < 0.001]. Both UMEC/VI and TIO improved SGRQ and rescue use in the two populations, with greater improvements in rescue use with UMEC/VI versus TIO. UMEC/VI reduced the risk of short-term clinically important deterioration versus TIO [hazard ratio; 95% confidence interval: MN: 0.66 (0.51-0.85); ITT: 0.62 (0.54-0.71), both P ≤ 0.001]. Adverse events were similar across both populations and treatments. Early use of dual-bronchodilator therapy has superior efficacy on lung function and may reduce the risk of short-term deterioration compared to monotherapy in symptomatic patients with COPD. GSK analysis 202066 (NCT01316900/DB2113360, NCT01316913/DB2113374, NCT01777334/ZEP

  16. A randomized, placebo-controlled trial of late Na current inhibition (ranolazine) in coronary microvascular dysfunction (CMD): impact on angina and myocardial perfusion reserve.

    Science.gov (United States)

    Bairey Merz, C Noel; Handberg, Eileen M; Shufelt, Chrisandra L; Mehta, Puja K; Minissian, Margo B; Wei, Janet; Thomson, Louise E J; Berman, Daniel S; Shaw, Leslee J; Petersen, John W; Brown, Garrett H; Anderson, R David; Shuster, Jonathan J; Cook-Wiens, Galen; Rogatko, André; Pepine, Carl J

    2016-05-14

    The mechanistic basis of the symptoms and signs of myocardial ischaemia in patients without obstructive coronary artery disease (CAD) and evidence of coronary microvascular dysfunction (CMD) is unclear. The aim of this study was to mechanistically test short-term late sodium current inhibition (ranolazine) in such subjects on angina, myocardial perfusion reserve index, and diastolic filling. Randomized, double-blind, placebo-controlled, crossover, mechanistic trial in subjects with evidence of CMD [invasive coronary reactivity testing or non-invasive cardiac magnetic resonance imaging myocardial perfusion reserve index (MPRI)]. Short-term oral ranolazine 500-1000 mg twice daily for 2 weeks vs. placebo. Angina measured by Seattle Angina Questionnaire (SAQ) and SAQ-7 (co-primaries), diary angina (secondary), stress MPRI, diastolic filling, quality of life (QoL). Of 128 (96% women) subjects, no treatment differences in the outcomes were observed. Peak heart rate was lower during pharmacological stress during ranolazine (-3.55 b.p.m., P < 0.001). The change in SAQ-7 directly correlated with the change in MPRI (correlation 0.25, P = 0.005). The change in MPRI predicted the change in SAQ QoL, adjusted for body mass index (BMI), prior myocardial infarction, and site (P = 0.0032). Low coronary flow reserve (CFR <2.5) subjects improved MPRI (P < 0.0137), SAQ angina frequency (P = 0.027), and SAQ-7 (P = 0.041). In this mechanistic trial among symptomatic subjects, no obstructive CAD, short-term late sodium current inhibition was not generally effective for SAQ angina. Angina and myocardial perfusion reserve changes were related, supporting the notion that strategies to improve ischaemia should be tested in these subjects. clinicaltrials.gov Identifier: NCT01342029. © The Author 2015. Published by Oxford University Press on behalf of the European Society of Cardiology.

  17. Sending-country violence and receiving-country discrimination: effects on the health of Colombian refugees in Ecuador.

    Science.gov (United States)

    Shedlin, Michele G; Decena, Carlos U; Noboa, Hugo; Betancourt, Óscar

    2014-02-01

    This study explored factors affecting the health and well being of recent refugees from Colombia in Ecuador. Data collection focused on how sending-country violence and structural violence in a new environment affect immigrant health vulnerability and risk behaviors. A qualitative approach included ethnographic observation, media content analysis, focus groups, and individual interviews with refugees (N = 137). The focus groups (5) provided perspectives on the research domains by sex workers; drug users; male and female refugees; and service providers. Social and economic marginalization are impacting the health and well being of this growing refugee population. Data illustrate how stigma and discrimination affect food and housing security, employment and health services, and shape vulnerabilities and health risks in a new receiving environment. Widespread discrimination in Ecuador reflects fears, misunderstanding, and stereotypes about Colombian refugees. For this displaced population, the sequelae of violence, combined with survival needs and lack of support and protections, shape new risks to health and well-being.

  18. Throughput Improvement for TCP with a Performance Enhancing Proxy Using a UDP-Like Packet Sending Policy

    Science.gov (United States)

    Wang, Hui; Nishida, Yuichi; Fukushima, Yukinobu; Yokohira, Tokumi; Wu, Zhen

    To improve TCP throughput even if the maximum receiving window size is small, a TCP performance enhancing proxy (PEP) using a UDP-like packet sending policy with error control has been proposed. The PEP operates on a router along a TCP connection. When the PEP receives a data packet from the source host, it transmits the packet to the destination host, copies the packet into the local buffer (PEP buffer) in case the packets need to be transmitted and sends a premature ACK acknowledging receipt of the packet to the source host. In the PEP, the number of prematurely acknowledged packets in the PEP buffer is limited to a fixed threshold (watermark) value to avoid network congestion. Although the watermark value should be adjusted to changes in the network conditions, watermark adjusting algorithms have not been investigated. In this paper, we propose a watermark adjusting algorithm the goal of which is to maximize the throughput of each connection as much as possible without excessively suppressing the throughputs of the other connections. In our proposed algorithm, a newly established connection uses the initial watermark value of zero to avoid drastic network congestion and increases the value as long as its throughput increases. In addition, when a new connection is established, every already-established connection halves its watermark value to allow the newly established connection to use some portion of the bandwidth and increases again as long as its throughput increases. We compare the proposed algorithm (CW method) with other methods: the FW method that uses a fixed large watermark value and the NP method that does not use the PEP. Numerical results with respect to throughput and fairness showed that the CW method is generally superior to the other two methods.

  19. Safety and Immunogenicity of the Recombinant BCG Vaccine AERAS-422 in Healthy BCG-naïve Adults: A Randomized, Active-controlled, First-in-human Phase 1 Trial.

    Science.gov (United States)

    Hoft, Daniel F; Blazevic, Azra; Selimovic, Asmir; Turan, Aldin; Tennant, Jan; Abate, Getahun; Fulkerson, John; Zak, Daniel E; Walker, Robert; McClain, Bruce; Sadoff, Jerry; Scott, Judy; Shepherd, Barbara; Ishmukhamedov, Jasur; Hokey, David A; Dheenadhayalan, Veerabadran; Shankar, Smitha; Amon, Lynn; Navarro, Garnet; Podyminogin, Rebecca; Aderem, Alan; Barker, Lew; Brennan, Michael; Wallis, Robert S; Gershon, Anne A; Gershon, Michael D; Steinberg, Sharon

    2016-05-01

    We report a first-in-human trial evaluating safety and immunogenicity of a recombinant BCG, AERAS-422, over-expressing TB antigens Ag85A, Ag85B, and Rv3407 and expressing mutant perfringolysin. This was a randomized, double-blind, dose-escalation trial in HIV-negative, healthy adult, BCG-naïve volunteers, negative for prior exposure to Mtb, at one US clinical site. Volunteers were randomized 2:1 at each dose level to receive a single intradermal dose of AERAS-422 (>10(5)-BCG (1-8×10(5)CFU). Randomization used an independently prepared randomly generated sequence of treatment assignments. The primary and secondary outcomes were safety and immunogenicity, respectively, assessed in all participants through 182days post-vaccination. ClinicalTrials.gov registration number: NCT01340820. Between Nov 2010 and Aug 2011, 24 volunteers were enrolled (AERAS-422 high dose, n=8; AERAS-422 low dose, n=8; Tice BCG, n=8); all were included in the safety and immunogenicity analyses. All 24 subjects had at least one adverse event, primarily expected local reactions. High dose AERAS-422 vaccination induced Ag85A- and Ag85B-specific lymphoproliferative responses and marked anti-mycobacterial activity in a whole blood bactericidal activity culture assay (WBA), but was associated with varicella zoster virus (VZV) reactivation in two vaccinees. These volunteers displayed high BCG-specific IFN-γ responses pre- and post-vaccination possibly predisposing them to autocrine/paracrine negative regulation of immune control of latent VZV. A systems biology transcriptomal approach identified positive correlations between post-vaccination T cell expression modules and WBA, and negative correlations between post-vaccination monocyte expression modules and WBA. The expression of one key macrophage marker (F4/80) was constitutively elevated in the two volunteers with zoster. The unexpected development of VZV in two of eight healthy adult vaccine recipients resulted in discontinuation of AERAS-422

  20. Antibioticoprofilaxia com ampicilina na rotura prematura das membranas: estudo randomizado e duplo cego Ampicillin prophylaxis in premature rupture of membranes: randomized and double-blind study

    Directory of Open Access Journals (Sweden)

    José Elias Soares da Rocha

    1999-06-01

    avoid or reduce maternal and perinatal infectious morbidity caused by premature rupture of membranes (PROM, and to extend the gestation period in those women. Methods: this was a prospective, randomized and double-blind study, carried out evaluating 121 pregnant women with PROM, randomized into two study groups. The treatment group (61 patients received ampicillin and the control group (60 patients received placebo. The placebo had the same characteristics as ampicillin (kind of packaging and color of the capsules and was used in the same time regimen. The considered parameters for maternal infection were febrile morbidity (fever index, and the presence of chorioamnionitis and/or endometritis. The studied neonatal parameters were Apgar score (1st and 5th minutes, bacterial colonization of auditory canal, and blood culture. The statistical tests performed were Fisher's exact test, Wilcoxon, and chi². Results: it was observed that ampicillin did not prolong the gestation, nor did it reduce the postpartum febrile morbidity or the rates of chorioamnionitis and/or endometritis. Ampicillin did not reduce the perinatal infectious morbidity nor improve the birth outcomes. All these results were consistent in cases of less than 72 h PROM. The limited number of cases with time of PROM greater than 72 h did not permit statistical analysis free of type II error. Conclusions: based on these results it was possible to conclude that the prophylactic use of ampicillin by pregnant women with less than 72 h PROM did not reduce either infectious maternal or perinatal morbidity. However, the presence of group B Streptococcus agalactiae in the blood culture from a neonate in the control group showed the necessity to start antibiotic treatment of pregnant women colonized by this microorganism.

  1. New insulin glargine 300 U/ml compared with glargine 100 U/ml in insulin-naïve people with type 2 diabetes on oral glucose-lowering drugs: a randomized controlled trial (EDITION 3).

    Science.gov (United States)

    Bolli, G B; Riddle, M C; Bergenstal, R M; Ziemen, M; Sestakauskas, K; Goyeau, H; Home, P D

    2015-04-01

    To compare the efficacy and safety of new insulin glargine 300 U/ml (Gla-300) with that of glargine 100 U/ml (Gla-100) in insulin-naïve people with type 2 diabetes using oral glucose-lowering drugs. The EDITION 3 study was a multicentre, open-label, parallel-group study. Participants were randomized to Gla-300 or Gla-100 once daily for 6 months, discontinuing sulphonylureas and glinides, with a dose titration aimed at achieving pre-breakfast plasma glucose concentrations of 4.4-5.6 mmol/l (80-100 mg/dl). The primary endpoint was change in glycated haemoglobin (HbA1c) from baseline to month 6. The main secondary endpoint was percentage of participants with ≥1 nocturnal confirmed [≤3.9 mmol/l (≤70 mg/dl)] or severe hypoglycaemia from week 9 to month 6. Other measures of glycaemia and hypoglycaemia, weight change and insulin dose were assessed. Randomized participants (n = 878) had a mean (standard deviation) age of 57.7 (10.1) years, diabetes duration 9.8 (6.4) years, body mass index 33.0 (6.7) kg/m(2) and HbA1c 8.54 (1.06) % [69.8 (11.6) mmol/mol]. HbA1c levels decreased by equivalent amounts with the two treatments; the least squares mean difference in change from baseline was 0.04 [95% confidence interval (CI) -0.09 to 0.17] % or 0.4 (-1.0 to 1.9) mmol/mol. Numerically fewer participants reported ≥1 nocturnal confirmed (≤3.9 mmol/l) or severe hypoglycaemia from week 9 to month 6 [relative risk (RR) 0.89 (95% CI 0.66 to 1.20)] with Gla-300 versus Gla-100; a significantly lower risk of hypoglycaemia with this definition was found over the 6-month treatment period [RR 0.76 (95% CI 0.59 to 0.99)]. No between-treatment differences in adverse events were identified. Gla-300 is as effective as Gla-100 in reducing HbA1c in insulin-naïve people with type 2 diabetes, with lower hypoglycaemia risk. © 2015 The Authors. Diabetes, Obesity and Metabolism published by John Wiley & Sons Ltd.

  2. Sending servers to Morocco

    CERN Multimedia

    Joannah Caborn Wengler

    2012-01-01

    Did you know that computer centres are like people? They breathe air in and out like a person, they have to be kept at the right temperature, and they can even be organ donors. As part of a regular cycle of equipment renewal, the CERN Computer Centre has just donated 161 retired servers to universities in Morocco.   Prof. Abdeslam Hoummada and CERN DG Rolf Heuer seeing off the servers on the beginning of their journey to Morocco. “Many people don’t realise, but the Computer Centre is like a living thing. You don’t just install equipment and it runs forever. We’re continually replacing machines, broken parts and improving things like the cooling.” Wayne Salter, Leader of the IT Computing Facilities Group, watches over the Computer Centre a bit like a nurse monitoring a patient’s temperature, especially since new international recommendations for computer centre environmental conditions were released. “A new international s...

  3. Send flere bureaukrater

    DEFF Research Database (Denmark)

    Veicherts, Nicolas Teodors

    2007-01-01

    Afghanistan. Det er ikke kun Taleban, der er fjenden. Fraværet af en markant og effektiv civil indsats for genopbygning og socioøkonomisk fremgang kan medføre, at den militære indsats viser sig Forgæves....

  4. Ensaios Clínicos Randomizados na ortopedia e traumatologia: avaliação sistemática da evidência nacional Randomized Controlled Trials in orthopedics and traumatology: systematic analysis of the national evidence

    Directory of Open Access Journals (Sweden)

    Vinícius Ynoe de Moraes

    2010-01-01

    Full Text Available OBJETIVO: Verificar se houve melhora da qualidade e quantidade dos ensaios clínicos randomizados (ECRs publicados na literatura nacional, por meio da aplicação de escores estruturados e validados na literatura. MÉTODOS: Selecionamos, eletronicamente, todas as edições das duas revistas indexadas e de escopo ortopédico da literatura nacional - Acta Ortopédica Brasileira (AOB e Revista Brasileira de Ortopedia (RBO, no período de 2000-2009, todos os ECRs publicados. Dois pesquisadores independentes identificaram e pontuaram os ECRs de acordo com as escalas de JADAD e do grupo de trauma musculoesquelético da Colaboração Cochrane. Os trabalhos selecionados foram agrupados: 1 pelo período de publicação 2000-2004 e 2004-2009; 2 periódico de publicação (AOB e RBO. RESULTADOS: Vinte e dois trabalhos foram selecionados, sendo10 da AOB e 12 da RBO. Não houve diferença entre o número proporcional (nECR/nTotal de trabalhos publicados de ensaios clínicos randomizados publicados nos dois periódicos (p = 0,458, assim como para os escores de JADAD (p = 0,722 e da Colaboração Cochrane (p = 0,630. CONCLUSÃO: A qualidade e quantidade relativa de ensaios clínicos randomizados nos periódicos analisados foi semelhante. Há uma tendência de melhora da qualidade; contudo, não há acréscimo da quantidade de ensaios clínicos randomizados nos dois períodos analisados.OBJECTIVE: To assess whether there was an improvement in the quality and quantity of randomized controlled trials (RCTs in nationally published journals through an application of standardized and validated scores. METHODS: We selected, electronically, for the period of 2000-2009, all RCTs published at the two indexed, orthopaedics-focused Brazilian journals: Acta Ortopédica Brasileira(AOB and Revista Brasileira de Ortopedia (RBO. These RCTs were identified and scored by two independent researchers according to the JADAD scale and Cochrane Bone, Joint and Muscle Trauma Group

  5. ASSESSMENT OF RIP-V1 AND OSPF-V2 PROTOCOL WITH CONSIDERATION OF CONVERGENCE CRITERIA AND SENDING PROTOCOLS TRAFFIC

    Directory of Open Access Journals (Sweden)

    Hamed Jelodar

    2014-03-01

    Full Text Available Routing Protocols are underlying principles in networks like internet, transport and mobile. Routing Protocols include a series of rules and algorithms that consider routing metric and select the best way for sending healthy data packets from origin to destination. Dynamic routing protocol compatible to topology has a changeable state. RIP and OSPF are dynamic routing protocol that we consider criteria like convergence and sending protocols traffic assessment RIP first version and OSPF second version. By the test we have done on OPNET stimulation we understood that the OSPF protocol was more efficient than RIP protocol.

  6. Effectiveness of intra-articular lidocaine injection for reduction of anterior shoulder dislocation: randomized clinical trial Efetividade da injeção intrarticular de lidocaína na redução das luxações anteriores do ombro: ensaio clínico randomizado

    Directory of Open Access Journals (Sweden)

    Marcel Jun Sugawara Tamaoki

    2012-01-01

    Full Text Available CONTEXT AND OBJECTIVE: Shoulder dislocation is the most common dislocation among the large joints. The aim here was to compare the effectiveness of reduction of acute anterior shoulder dislocation with or without articular anesthesia. DESIGN AND SETTING: Prospective randomized trial conducted in Escola Paulista de Medicina, Universidade Federal de São Paulo (EPM-Unifesp. METHODS: From March 2008 to December 2009, 42 patients with shoulder dislocation were recruited. Reductions using traction-countertraction for acute anterior shoulder dislocation with and without lidocaine articular anesthesia were compared. As the primary outcome, pain was assessed through application of a visual analogue scale before reduction, and one and five minutes after the reduction maneuver was performed. Complications were also assessed. RESULTS: Forty-two patients were included: 20 in the group without analgesia (control group and 22 in the group that received intra-articular lidocaine injection. The group that received intra-articular lidocaine had a statistically greater decrease in pain over time than shown by the control group, both in the first minute (respectively: mean 2.1 (0 to 5.0, standard deviation, SD 1.3, versus mean 4.9 (2.0 to 7.0, SD 1.5; P CONTEXTO E OBJETIVO: A luxação do ombro é a mais frequente luxação das grandes articulações. O objetivo foi comparar a efetividade da redução da luxação anterior aguda do ombro, com ou sem anestesia articular. TIPO DE ESTUDO E LOCAL: Ensaio clínico randomizado desenvolvido na Escola Paulista de Medicina - Universidade Federal de São Paulo (EPM-Unifesp. MÉTODOS: De março de 2008 a dezembro de 2009 foram recrutados 42 pacientes com luxação anterior do ombro agudas. Foi comparada a redução de tração e contra-tração com e sem anestesia intra-articular com lidocaína. Como desfecho primário, a dor foi avaliada por meio da escala visual analógica antes da redução e um e cinco minutos após a

  7. Predictors of discontinuation of benzodiazepine prescription after sending a letter to long-term benzodiazepine users in family practice.

    Science.gov (United States)

    Gorgels, W J M J; Oude Voshaar, R C; Mol, A J J; van de Lisdonk, E H; van Balkom, A J L M; Breteler, M H M; van den Hoogen, H J M; Mulder, J; Zitman, F G

    2006-02-01

    Predictors of benzodiazepine discontinuation after sending a discontinuation letter by the family practitioner have not been established sufficiently. To identify predictors of short- and long-term discontinuation of benzodiazepine use and relapse in use after a minimal intervention with a discontinuation letter followed by an offer for an evaluation consultation. Predictors of benzodiazepine discontinuation and relapse in use were studied by logistic regression analysis and survival analysis within a family practice population of long-term benzodiazepine users (n = 1707) addressed by a discontinuation letter and followed for 21 months. A lower baseline prescription, a shorter duration of use, male gender and use of an agent with a half-life time discontinuation in the short (6 months) and long term (21 months). Multiple agent use at baseline, use of antidepressants at 6 months and benzodiazepine type (anxiolytic/hypnotic) at baseline predicted relapse. Attendance at an evaluation consultation 3 months after the letter was sent was not predictive of discontinuation or relapse. Amount of baseline use and duration of use are the main determinative characteristics of successful discontinuation. The discontinuation letter intervention is suitable for use with a broad group of long-term benzodiazepine users in family practice and can be used as a first step within a stepped care approach to decrease long-term benzodiazepine use.

  8. TOD-Tree: Task-Overlapped Direct Send Tree Image Compositing for Hybrid MPI Parallelism and GPUs.

    Science.gov (United States)

    Grosset, A V Pascal; Prasad, Manasa; Christensen, Cameron; Knoll, Aaron; Hansen, Charles

    2017-06-01

    Modern supercomputers have thousands of nodes, each with CPUs and/or GPUs capable of several teraflops. However, the network connecting these nodes is relatively slow, on the order of gigabits per second. For time-critical workloads such as interactive visualization, the bottleneck is no longer computation but communication. In this paper, we present an image compositing algorithm that works on both CPU-only and GPU-accelerated supercomputers and focuses on communication avoidance and overlapping communication with computation at the expense of evenly balancing the workload. The algorithm has three stages: a parallel direct send stage, followed by a tree compositing stage and a gather stage. We compare our algorithm with radix-k and binary-swap from the IceT library in a hybrid OpenMP/MPI setting on the Stampede and Edison supercomputers, show strong scaling results and explain how we generally achieve better performance than these two algorithms. We developed a GPU-based image compositing algorithm where we use CUDA kernels for computation and GPU Direct RDMA for inter-node GPU communication. We tested the algorithm on the Piz Daint GPU-accelerated supercomputer and show that we achieve performance on par with CPUs. Last, we introduce a workflow in which both rendering and compositing are done on the GPU.

  9. Sending and Receiving Text Messages with Sexual Content: Relations with Early Sexual Activity and Borderline Personality Features in Late Adolescence.

    Science.gov (United States)

    Brinkley, Dawn Y; Ackerman, Robert A; Ehrenreich, Samuel E; Underwood, Marion K

    2017-05-01

    This research examined adolescents' written text messages with sexual content to investigate how sexting relates to sexual activity and borderline personality features. Participants (N = 181, 85 girls) completed a measure of borderline personality features prior to 10th grade and were subsequently given smartphones configured to capture the content of their text messages. Four days of text messaging were micro-coded for content related to sex. Following 12th grade, participants reported on their sexual activity and again completed a measure of borderline personality features. Results showed that engaging in sexting at age 16 was associated with reporting an early sexual debut, having sexual intercourse experience, having multiple sex partners, and engaging in drug use in combination with sexual activity two years later. Girls engaging in sex talk were more likely to have had sexual intercourse by age 18. Text messaging about hypothetical sex in grade 10 also predicted borderline personality features at age 18. These findings suggest that sending text messages with sexual content poses risks for adolescents. Programs to prevent risky sexual activity and to promote psychological health could be enhanced by teaching adolescents to use digital communication responsibly.

  10. D-SEND#2搭載カメラの検討と試験結果

    OpenAIRE

    高戸谷, 健; 平野, 義鎭; Takatoya, Takeshi; Hirano, Yoshiyasu

    2016-01-01

    ソニックブームを半減させる技術の獲得に向けて小型の無人機供試体を用いた低ソニックブーム設計概念実証プロジェクトを進め,第二回飛行試験を2015年7月24日に実施した.D-SEND#2 供試体に搭載した搭載カメラについて仕様を定め,候補を選定し,確認試験を行い搭載カメラの構成を決定した.同時に供試体のプライムメーカのFHIやJAXA内との調整を実施して,搭載カメラを載せる位置やカメラカバーの形状,作業手順などを順次決めていった.第二回飛行試験においては,放球から着地までの映像を取得することができた成果について報告する....

  11. Sending-Country Violence & Receiving-Country Discrimination: Effects on the Health of Colombian Refugees in Ecuador

    Science.gov (United States)

    Shedlin, Michele G.; Decena, Carlos U.; Noboa, Hugo; Betancourt, Óscar

    2013-01-01

    BACKGROUND This study explored factors affecting the health and well being of recent refugees from Colombia in Ecuador. Data collection focused on how sending-country violence and structural violence in a new environment affect immigrant health vulnerability and risk behaviors. METHODS A qualitative approach included ethnographic observation, media content analysis, focus groups, and individual interviews with refugees (N=137). The focus groups (5) provided perspectives on the research domains by sex workers; drug users; male and female refugees; and service providers. RESULTS Social and economic marginalization are impacting the health and well being of this growing refugee population. Data illustrate how stigma and discrimination affect food and housing security, employment and health services, and shape vulnerabilities and health risks in a new receiving environment. DISCUSSION Widespread discrimination in Ecuador reflects fears, misunderstanding, and stereotypes about Colombian refugees. For this displaced population, the sequelae of violence, combined with survival needs and lack of support and protections, shape new risks to health and well-being. PMID:23377565

  12. Circular Migration by Mexican Female Sex Workers Who are Injection Drug Users: Implications for HIV in Mexican Sending Communities

    Science.gov (United States)

    Ojeda, Victoria D.; Burgos, José Luis; Hiller, Sarah P.; Lozada, Remedios; Rangel, Gudelia; Vera, Alicia; Artamonova, Irina; Rodriguez, Carlos Magis

    2013-01-01

    Background Circular migration and injection drug use increase the risk of HIV transmission in sending communities. We describe female sex workers who are injection drug users’ (FSW-IDUs) circular migration and drug use behaviors. Methods Between 2008-2010, 258 migrant FSW-IDUs residing in Tijuana and Ciudad Juarez, Mexico responded to questionnaires. Results 24% of FSW-IDUs were circular migrants. HIV prevalence was 3.3% in circular migrants and 6.1% in non-circular migrants; 50% of circular and 82% of non-circular migrants were unaware of their HIV infection. Among circular migrants, 44% (n=27) consumed illicit drugs in their birthplace; 70% of these (n=20) injected drugs and one-half of injectors shared injection equipment in their birthplace. Women reporting active social relationships were significantly more likely to return home. Discussion Circular migrant FSW-IDUs exhibit multiple HIV risks and opportunities for bridging populations. Regular HIV testing and treatment and access to substance use services is critical for FSW-IDUs and their sexual/drug-using contacts. PMID:21833727

  13. Sodium lactate improves renal microvascular thrombosis compared to sodium bicarbonate and 0.9% NaCl in a porcine model of endotoxic shock: an experimental randomized open label controlled study.

    Science.gov (United States)

    Duburcq, Thibault; Durand, Arthur; Tournoys, Antoine; Gnemmi, Viviane; Gmyr, Valery; Pattou, François; Jourdain, Mercedes; Tamion, Fabienne; Besnier, Emmanuel; Préau, Sebastien; Parmentier-Decrucq, Erika; Mathieu, Daniel; Poissy, Julien; Favory, Raphaël

    2018-02-14

    Sodium lactate seemed to improve fluid balance and avoid fluid overload. The objective of this study was to determine if these beneficial effects can be at least partly explained by an improvement in disseminated intravascular coagulation (DIC)-associated renal microvascular thrombosis. Ancillary work of an interventional randomized open label controlled experimental study. Fifteen female "Large White" pigs (2 months old) were challenged with intravenous infusion of E. coli endotoxin. Three groups of five animals were randomly assigned to receive different fluids: a treatment group received sodium lactate 11.2% (SL group); an isotonic control group received 0.9% NaCl (NC group); a hypertonic control group, with the same amount of osmoles and sodium than SL group, received sodium bicarbonate 8.4% (SB group). Glomerular filtration rate (GFR) markers, coagulation and inflammation parameters were measured over a 5-h period. Immediately after euthanasia, kidneys were withdrawn for histological study. Statistical analysis was performed with nonparametric tests and the Dunn correction for multiple comparisons. A p < 0.05 was considered significant. The direct immunofluorescence study revealed that the percentage of capillary sections thrombosed in glomerulus were significantly lesser in SL group [5 (0-28) %] compared to NC [64 (43-79) %, p = 0.01] and SB [64 (43-79), p = 0.03] groups. Alterations in platelet count and fibrinogen level occurred earlier and were significantly more pronounced in both control groups compared to SL group (p < 0.05 at 210 and 300 min). The increase in thrombin-antithrombin complexes was significantly higher in NC [754 (367-945) μg/mL; p = 0.03] and SB [463 (249-592) μg/mL; p = 0.03] groups than in SL group [176 (37-265) μg/mL]. At the end of the experiment, creatinine clearance was significantly higher in SL group [55.46 (30.07-67.85) mL/min] compared to NC group [1.52 (0.17-27.67) mL/min, p = 0.03]. In this study, we

  14. Randomized, Noncomparative, Phase II Trial of Early Switch From Docetaxel to Cabazitaxel or Vice Versa, With Integrated Biomarker Analysis, in Men With Chemotherapy-Naïve, Metastatic, Castration-Resistant Prostate Cancer.

    Science.gov (United States)

    Antonarakis, Emmanuel S; Tagawa, Scott T; Galletti, Giuseppe; Worroll, Daniel; Ballman, Karla; Vanhuyse, Marie; Sonpavde, Guru; North, Scott; Albany, Costantine; Tsao, Che-Kai; Stewart, John; Zaher, Atef; Szatrowski, Ted; Zhou, Wei; Gjyrezi, Ada; Tasaki, Shinsuke; Portella, Luigi; Bai, Yang; Lannin, Timothy B; Suri, Shalu; Gruber, Conor N; Pratt, Erica D; Kirby, Brian J; Eisenberger, Mario A; Nanus, David M; Saad, Fred; Giannakakou, Paraskevi

    2017-10-01

    Purpose The TAXYNERGY trial ( ClinicalTrials.gov identifier: NCT01718353) evaluated clinical benefit from early taxane switch and circulating tumor cell (CTC) biomarkers to interrogate mechanisms of sensitivity or resistance to taxanes in men with chemotherapy-naïve, metastatic, castration-resistant prostate cancer. Patients and Methods Patients were randomly assigned 2:1 to docetaxel or cabazitaxel. Men who did not achieve ≥ 30% prostate-specific antigen (PSA) decline by cycle 4 (C4) switched taxane. The primary clinical endpoint was confirmed ≥ 50% PSA decline versus historical control (TAX327). The primary biomarker endpoint was analysis of post-treatment CTCs to confirm the hypothesis that clinical response was associated with taxane drug-target engagement, evidenced by decreased percent androgen receptor nuclear localization (%ARNL) and increased microtubule bundling. Results Sixty-three patients were randomly assigned to docetaxel (n = 41) or cabazitaxel (n = 22); 44.4% received prior potent androgen receptor-targeted therapy. Overall, 35 patients (55.6%) had confirmed ≥ 50% PSA responses, exceeding the historical control rate of 45.4% (TAX327). Of 61 treated patients, 33 (54.1%) had ≥ 30% PSA declines by C4 and did not switch taxane, 15 patients (24.6%) who did not achieve ≥ 30% PSA declines by C4 switched taxane, and 13 patients (21.3%) discontinued therapy before or at C4. Of patients switching taxane, 46.7% subsequently achieved ≥ 50% PSA decrease. In 26 CTC-evaluable patients, taxane-induced decrease in %ARNL (cycle 1 day 1 v cycle 1 day 8) was associated with a higher rate of ≥ 50% PSA decrease at C4 ( P = .009). Median composite progression-free survival was 9.1 months (95% CI, 4.9 to 11.7 months); median overall survival was not reached at 14 months. Common grade 3 or 4 adverse events included fatigue (13.1%) and febrile neutropenia (11.5%). Conclusion The early taxane switch strategy was associated with improved PSA response rates

  15. The effects of EPA and DHA enriched fish oil on nutritional and immunological markers of treatment naïve breast cancer patients: a randomized double-blind controlled trial.

    Science.gov (United States)

    Paixão, Elemárcia Martins da Silva; Oliveira, Ana Carolina de M; Pizato, Nathalia; Muniz-Junqueira, Maria Imaculada; Magalhães, Kelly G; Nakano, Eduardo Yoshio; Ito, Marina K

    2017-10-23

    We evaluated the effects of eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids enriched fish oil (FO) on nutritional and immunological parameters of treatment naïve breast cancer patients. In a randomized double blind controlled trial, the FO group (FG) patients were supplemented with 2 g/ day of FO concentrate containing 1.8 g of n-3 fatty acids during 30 days. The placebo group (PG) received 2 g/ day of mineral oil. At baseline and after the intervention, plasma levels of n-3 fatty acids, dietary intake, weight, body composition, biochemical and immunological markers were assessed. At the end of the intervention period, no between group differences were observed regarding anthropometric parameters. There was a significant increase in the plasma phospholipid EPA (p = 0.004), DHA (p = 0.007) of the FG patients. In FG patients the percentages of peripheral blood CD4(+) T lymphocytes and serum high sensitivity C-reactive protein (hsCRP) levels were maintained while in PG patients there was a significant increase in hsCRP (p = 0.024). We also observed a significant reduction in the percentage of CD4(+) T lymphocytes in the peripheral blood (p = 0.042) of PG patients. No changes in serum proinflammatory cytokine and prostaglandin E2 levels were observed. Supplementation of newly diagnosed breast cancer patients with EPA and DHA led to a significant change in the composition of plasma fatty acids, maintained the level of CD4(+) T cells and serum levels of hsCRP, suggestive of a beneficial effect on the immune system and less active inflammatory response. Brazilian Clinical Trials Registry (REBEC): RBR-2b2hqh. Registered 29 April 2013, retrospectively registered.

  16. Vardenafil improves sexual function and treatment satisfaction in couples affected by erectile dysfunction (ED): a randomized, double-blind, placebo-controlled trial in PDE5 inhibitor-naïve men with ED and their partners.

    Science.gov (United States)

    Edwards, David; Hackett, Geoff; Collins, Owen; Curram, John

    2006-11-01

    Erectile dysfunction (ED) is a common condition with diverse sequelae affecting men and their women partners. The FINDER study aimed to evaluate the efficacy and tolerability of the phosphodiesterase type-5 (PDE5) inhibitor, vardenafil, in a broad population of PDE5-naïve men with ED of different etiologies and severity and included their partners' assessments of treatment with vardenafil. Men with ED (N = 260) were randomized to receive either vardenafil or placebo in a multicenter, flexible-dose study. Primary efficacy variables were patients' responses to the Global Assessment Question (GAQ), and Sexual Encounter Profile questions 2 and 3 (SEP2 and SEP3). Compared with placebo, vardenafil significantly improved rates of successful "Yes" responses to SEP3 ("Did your erection last long enough for you to have successful intercourse?") (49% placebo vs. 78% vardenafil at last period carried forward [LPCF]; P < 0.0001), SEP2 ("Were you able to insert your penis into your partner's vagina?") (65% placebo vs. 85% vardenafil at LPCF; P < 0.0001), and GAQ (36% placebo vs. 83% vardenafil at last observation carried forward; P < 0.0001). In addition, patients' and their partners' Treatment Satisfaction Scale (TSS) scores were statistically significantly improved across each of the TSS domains (satisfaction with orgasm, ease with erection, confidence, pleasure, erectile function satisfaction, and satisfaction with medication) in the vardenafil group compared with the placebo group. Vardenafil improved sexual function to the extent that both patients and their partners expressed a considerable and agreed level of satisfaction with treatment.

  17. Efficacy and Safety of Once-Daily Insulin Degludec/Insulin Aspart versus Insulin Glargine (U100 for 52 Weeks in Insulin-Naïve Patients with Type 2 Diabetes: A Randomized Controlled Trial.

    Directory of Open Access Journals (Sweden)

    Ajay Kumar

    Full Text Available The efficacy and safety of insulin degludec/insulin aspart (IDegAsp once daily (OD compared with insulin glargine U100 (IGlar OD over 52 weeks in insulin-naïve adults with type 2 diabetes mellitus (T2DM was investigated.In this open-label, parallel-group treat-to-target trial, participants were randomized (1:1 to receive IDegAsp OD (breakfast, n = 266 or IGlar OD (as per label, n = 264. Participants then entered a 26-week extension phase (IDegAsp OD, n = 192; IGlar OD, n = 221. The primary endpoint was change from baseline to Week 26 in HbA1c.After 26 and 52 weeks, mean HbA1c decreased to similar levels in both groups. After 52 weeks, the mean estimated treatment difference was -0.08% (-0.26, 0.09 95%CI, confirming the non-inferiority of IDegAsp OD versus IGlar OD evaluated at Week 26. After 52 weeks, there was a similar reduction in mean fasting plasma glucose in both treatment groups. The rate of confirmed hypoglycemic episodes was 86% higher (p < 0.0001 whereas the rate of nocturnal hypoglycemia was 75% lower (p < 0.0001 for IDegAsp versus IGlar.Nocturnal-confirmed hypoglycemia was higher with IGlar whereas overall and diurnal hypoglycemia were higher with IDegAsp dosed at breakfast. These results highlight the importance of administration of IDegAsp with the main meal of the day, tailored to the individual patient's needs.ClinicalTrials.gov: NCT01045707 [core] and NCT01169766 [ext].

  18. A prospective randomized double blind placebo controlled crossover study of fluoxetine efficacy in the prophylaxis of chronic daily headache in children and adolescents Estudo randomizado prospectivo duplo-cego cruzado controlado com placebo da eficácia da fluoxetina na profilaxia da cefaléia crônica diária na infância e adolescência

    Directory of Open Access Journals (Sweden)

    José Luiz Dias Gherpelli

    2005-09-01

    Full Text Available Thirty-two children (21 female and 11 male, between 7 and 14 years old, with chronic daily headache (CDH were consecutively included in a prospective, randomized, double blind, placebo controlled crossover study. The patients were divided in group I (fluoxetine vs. placebo, with 17 patients and group II (placebo vs. fluoxetine, with 15 patients. After one month of baseline headache frequency recording, the patients received fluoxetine in dosages from 0.25 to 0.50 mg/kg for three months. A wash out period of one month was followed by another three months treatment period. Results showed a significant decrease in headache frequency in the study period [78% reduction in group I (pTrinta e duas crianças (21 feminino, 11 masculino, com idades entre 7 e 14 anos, com cefaléia crônica diária (CCD foram incluídos consecutivamente no estudo prospectivo, randomizado, duplo-cego, cruzado com placebo. Os pacientes foram divididos em grupo I (fluoxetina vs. placebo, com 17 pacientes, e grupo II (placebo vs. fluoxetina , com 15 pacientes. Após um mês de registro da freqüência da cefaléia, os pacientes receberam fluoxetina em doses de 0,25-0,5 mg/kg por três meses. Após período de interrupção da droga de um mês, seguiu-se novo período de três meses de tratamento. Os resultados mostraram diminuição estatisticamente significativa da freqüência da cefaléia [78% de redução no grupo I (p<0,025 e 45% de redução no grupo II (p<0,025]. Efeitos colaterais gastrointestinais ocorreram em 9 pacientes (29% na vigência da fluoxetina, comparado com 3 (10% com placebo. Concluímos que não houve diferença entre o efeito da fluoxetina e do placebo na profilaxia da CCD em crianças e adolescentes.

  19. Randomization tests

    CERN Document Server

    Edgington, Eugene

    2007-01-01

    Statistical Tests That Do Not Require Random Sampling Randomization Tests Numerical Examples Randomization Tests and Nonrandom Samples The Prevalence of Nonrandom Samples in Experiments The Irrelevance of Random Samples for the Typical Experiment Generalizing from Nonrandom Samples Intelligibility Respect for the Validity of Randomization Tests Versatility Practicality Precursors of Randomization Tests Other Applications of Permutation Tests Questions and Exercises Notes References Randomized Experiments Unique Benefits of Experiments Experimentation without Mani

  20. A phase 3, double-blind, randomized placebo-controlled efficacy and safety study of abiraterone acetate in chemotherapy-naïve patients with mCRPC in China, Malaysia, Thailand and Russia

    Directory of Open Access Journals (Sweden)

    Dingwei Ye

    2017-04-01

    Conclusion: Interim analysis confirmed favorable benefit-to-risk ratio of abiraterone in chemotherapy-naïve men with mCRPC, consistent with global study, thus supporting use of abiraterone in this patient population.

  1. A randomized, double-blind, parallel, single-site pilot trial to compare two different starting doses of methotrexate in methotrexate-naïve adult patients with rheumatoid arthritis.

    Science.gov (United States)

    Hobl, Eva-Luise; Mader, Robert M; Jilma, Bernd; Duhm, Bernhard; Mustak, Monika; Bröll, Hans; Högger, Petra; Erlacher, Ludwig

    2012-05-01

    Methotrexate (MTX) is a cornerstone in the treatment of rheumatoid arthritis. Despite its widespread use, expert opinions differ about the optimal MTX starting dosage to achieve rapid onset of action while averting increased occurrence of adverse effects. Plasma concentrations have not been assessed in previous studies that monitored clinical efficacy. This study was performed to compare the pharmacokinetic parameters and clinical response of a standard (15 mg) and an accelerated (25 mg) dosing regimen, each administered orally once a week. This randomized, controlled, double-blind, parallel, single-site study included 19 MTX-naïve patients older than 18 years with rheumatoid arthritis. Patients participated for 16 weeks. Disease activity was assessed using the Disease Activity Score in 28 joints (DAS-28) as the primary outcome parameter. Plasma MTX concentrations were measured using HPLC at weeks 1, 5, 10, and 16. Tolerability was assessed via routine blood analysis (hematology and clinical chemistry) and a patient questionnaire to monitor adverse events. Reported or observed adverse events were recorded along with information about their severity and causal relationship to the study medication. Nineteen white patients (13 women and 6 men; mean age, 56 years; and mean weight, 74 kg) participated. At study entry, mean (SD) DAS-28-4v (erythrocyte sedimentation rate) was 4.73 (1.02). Health Assessment Questionnaire scores were 1.45 (0.85); for C-reactive protein, 11.45 (10.04) mg/dL; for alkaline phosphatase, 73.58 (19.91) U/L; for aspartate aminotransferase, 23.32 (7.13) U/L; and for creatinine, 0.87 (0.22) mg/dL. Although pharmacokinetic parameters such as AUC and C(max) were significantly higher after the accelerated dosing regimen, clinical activity scores (DAS-28) and inflammation parameters (C-reactive protein) did not indicate a significant benefit of an accelerated starting regimen. Considering toxicity, no elevation in liver function enzymes and no decrease

  2. Why and How Do Parents Decide to Send Their Children to the Interdistrict School Choice Program at the Magnet Program for Math and Science

    Science.gov (United States)

    Doyle, Kevin S.

    The New Jersey Interdistrict School Choice Program allows parents to send their students to schools outside of their local school district. Determining why parents send their students to choice schools is important to school leaders who are trying to attract new students, as well as those who are trying to retain their current students. This study examined the reasons why parents decided to send their students to the Magnet Program for Math and Science (MP4M&S), a school choice program in a suburban school district in northwest New Jersey, during the 2015- 2016 school year. A large volume of research has focused on school choice programs in urban and poor communities. This study addressed the gap in the research by focusing on an affluent suburban school district. This mixed methods study focused on three areas, why parents choose to send their students to the MP4M&S, what criteria they used to make their decision, and where they got their information. Research shows that these three areas of focus can be influenced by parental level of education, socioeconomic status, geographic location, academic rigor, school quality, and school environment. Parents from different groups, based upon their out-of-district status, were interviewed. The information from the interviews was used to focus a survey that was given to the families of all 137 students in the MP4M&S during the 2015-2016 school year. The results of this study show that parents found the academic focus, academic rigor, the school environment, the original research project, the activity offerings, and the economics involved in attending the program to be important attractors. The study also found that the Information Nights, the school website, and interactions with members of the MP4M&S community to be important sources of information. Finally, the study found that there were few differences between in and out-of-district parents when assigning importance to both the attractors and the sources in the study

  3. Análises da persistência na lactação de vacas da raça Holandesa, usando produção no dia do controle e modelo de regressão aleatória Analysis of persistency in the lactation of Holstein cows using test-day yield and random regression model

    Directory of Open Access Journals (Sweden)

    Jaime Araujo Cobuci

    2004-06-01

    Full Text Available Foram utilizados 87.045 registros de produção de leite, na primeira lactação, de 11.023 vacas da raça Holandesa, obtidos nos anos de 1997 a 2001, em diferentes rebanhos distribuídos em dez núcleos do Estado de Minas Gerais. Foram avaliados seis tipos de mensuração da persistência na lactação utilizando-se os valores genéticos da produção de leite, obtidos por meio do modelo de regressão aleatória - MRA. Utilizou-se a função de Wilmink na descrição dos efeitos aleatórios e fixos, pelo MRA. As estimativas de herdabilidade e de correlação genética, para as várias mensurações da persistência na lactação, variaram em decorrência da definição da persistência. As estimativas de herdabilidade para persistência na lactação variaram de 0,11 a 0,27 e as estimativas de correlação genética entre as mensurações da persistência na lactação e produção de leite até 305 dias, de -0,31 a 0,55, indicando que a persistência na lactação é uma característica de moderada herdabilidade e pouco correlacionada com a produção de leite até 305 dias. A seleção de animais para persistência na lactação, com o objetivo de alterar a forma da curva de lactação, pode ser eficiente.A total of 87,045 milk yield records of 11,023 first-parity Holstein cows was utilized, obtained from 1997 to 2001 from different herds of 10 Minas Gerais locations. Six types of persistency measures in lactation were evaluated using milk yield breeding values, obtained by means of Random Regression Model - RRM. The Wilmink function was used to describe the random and fixed effects by RRM. Heritability estimates and genetic correlations for various persistency measures in lactation were dependent on the definition of persistency. The heritability estimates for persistency in lactation ranged from 0.11 to 0.27 and the genetic variations among persistency measures in lactation and milk yield up to d 305 ranged from -0.31 to 0.55, showing that

  4. Developing a bone mineral density test result letter to send to patients: a mixed-methods study

    Directory of Open Access Journals (Sweden)

    Edmonds SW

    2014-06-01

    Full Text Available Stephanie W Edmonds,1,2 Samantha L Solimeo,3 Xin Lu,1 Douglas W Roblin,4,8 Kenneth G Saag,5 Peter Cram6,7 1Department of Internal Medicine, 2College of Nursing, University of Iowa, Iowa City, IA, USA; 3Center for Comprehensive Access and Delivery Research and Evaluation, Iowa City Veterans Affairs Health Care System, Iowa City, IA, USA; 4Kaiser Permanente of Atlanta, Atlanta, GA, USA; 5Department of Rheumatology, University of Alabama at Birmingham, Birmingham, AL, USA; 6Faculty of Medicine, University of Toronto, Toronto, ON, Canada; 7University Health Network and Mount Sinai Hospital, Toronto, ON, Canada; 8School of Public Health, Georgia State University, Atlanta, GA, USA Purpose: To use a mixed-methods approach to develop a letter that can be used to notify patients of their bone mineral density (BMD results by mail that may activate patients in their bone-related health care. Patients and methods: A multidisciplinary team developed three versions of a letter for reporting BMD results to patients. Trained interviewers presented these letters in a random order to a convenience sample of adults, aged 50 years and older, at two different health care systems. We conducted structured interviews to examine the respondents’ preferences and comprehension among the various letters. Results: A total of 142 participants completed the interview. A majority of the participants were female (64.1% and white (76.1%. A plurality of the participants identified a specific version of the three letters as both their preferred version (45.2%; P<0.001 and as the easiest to understand (44.6%; P<0.01. A majority of participants preferred that the letters include specific next steps for improving their bone health. Conclusion: Using a mixed-methods approach, we were able to develop and optimize a printed letter for communicating a complex test result (BMD to patients. Our results may offer guidance to clinicians, administrators, and researchers who are

  5. Private randomness expansion with untrusted devices

    Energy Technology Data Exchange (ETDEWEB)

    Colbeck, Roger; Kent, Adrian, E-mail: rcolbeck@perimeterinstitute.ca, E-mail: a.p.a.kent@damtp.cam.ac.uk [Perimeter Institute for Theoretical Physics, 31 Caroline Street North, Waterloo, ON N2L 2Y5 (Canada)

    2011-03-04

    Randomness is an important resource for many applications, from gambling to secure communication. However, guaranteeing that the output from a candidate random source could not have been predicted by an outside party is a challenging task, and many supposedly random sources used today provide no such guarantee. Quantum solutions to this problem exist, for example a device which internally sends a photon through a beamsplitter and observes on which side it emerges, but, presently, such solutions require the user to trust the internal workings of the device. Here, we seek to go beyond this limitation by asking whether randomness can be generated using untrusted devices-even ones created by an adversarial agent-while providing a guarantee that no outside party (including the agent) can predict it. Since this is easily seen to be impossible unless the user has an initially private random string, the task we investigate here is private randomness expansion. We introduce a protocol for private randomness expansion with untrusted devices which is designed to take as input an initially private random string and produce as output a longer private random string. We point out that private randomness expansion protocols are generally vulnerable to attacks that can render the initial string partially insecure, even though that string is used only inside a secure laboratory; our protocol is designed to remove this previously unconsidered vulnerability by privacy amplification. We also discuss extensions of our protocol designed to generate an arbitrarily long random string from a finite initially private random string. The security of these protocols against the most general attacks is left as an open question.

  6. Efeito da caminhada em esteira na acuidade proprioceptiva do tornozelo em mulheres jovens saudáveis: ensaio clínico randomizado = Effect of treadmill walking on ankle proprioceptive acuity in healthy young women: a randomized clinical trial

    Directory of Open Access Journals (Sweden)

    Briani, Ronaldo Valdir

    2015-01-01

    Full Text Available Objetivos: Avaliar o efeito da caminhada em esteira na acuidade proprioceptiva do tornozelo de mulheres jovens saudáveis. Métodos: Para este ensaio clínico randomizado foram selecionadas 20 mulheres entre 18 e 30 anos com um nível baixo de atividade física segundo a classificação IPAQ (Questionário Internacional de Nível de Atividade Física. As participantes foram divididas em dois grupos de 10 componentes, o Grupo Exercício, que realizou 10 sessões de caminhada em esteira, e o Grupo Controle, que não foi submetido a nenhuma intervenção. A acuidade proprioceptiva do tornozelo foi avaliada pré e pós-intervenção por meio do Star Excursion Balance Test. Após ser confirmada a normalidade dos dados, foi utilizada a análise de variância com delineamento misto para comparação entre os grupos e entre as avaliações pré e pós-intervenção. Resultados: Não foram encontradas diferenças significativas na execução do Star Excursion Balance Test comparando as avaliações pré e pós-intervanção em ambos os grupos. Também não foram encontradas diferenças entre os dois grupos comparando as variações percentuais entre as duas avaliações. Conclusões: Nas condições testadas, um programa de 10 sessões de caminhada em esteira não foi capaz de promover adaptações na acuidade proprioceptiva do tornozelo em mulheres jovens saudáveis

  7. The NA62 GigaTracker

    CERN Document Server

    Perrin-Terrin, Mathieu

    2015-01-01

    The GigaTracker is an hybrid silicon pixel detector built for the NA62 experiment aiming at measuring the branching fraction of the ultra-rare kaon decay K + ! p + n ̄ n at the CERN SPS. The detector has to track particles in a beam with a flux reaching 1.3 MHz/mm 2 and provide single-hit timing with 200ps RMS resolution for a total material budget of less than 1.5 X 0 . The tracker comprises three 60.8mm 27mm stations installed in vacuum ( 10$^{-6}$ mbar) and cooled with liquid C 6 F 14 circulating through micro-channels etched inside few hundred of microns thick silicon plates. Each station is composed of a 200 m m thick silicon sensor readout by 2 x 5 cus- tom 100 m m thick ASIC, called TDCPix. Each chip contains 40 x 45 asynchronous pixels, each 300 m m x 300 m m and is instrumented with 100ps bin time-to-digital converters. In order to cope with the high rate, the TDCPix is equipped with four 3.2Gb/s serialisers sending out the data. We will describe the detector and the results from the 2014 NA62 ru...

  8. The NA62 GigaTracker

    Science.gov (United States)

    Aglieri Rinella, G.; Feito, D. Alvarez; Arcidiacono, R.; Biino, C.; Bonacini, S.; Ceccucci, A.; Chiozzi, S.; Gil, E. Cortina; Ramusino, A. Cotta; Degrange, J.; Fiorini, M.; Gamberini, E.; Gianoli, A.; Kaplon, J.; Kluge, A.; Mapelli, A.; Marchetto, F.; Minucci, E.; Morel, M.; Noël, J.; Noy, M.; Perktold, L.; Perrin-Terrin, M.; Petagna, P.; Petrucci, F.; Poltorak, K.; Romagnoli, G.; Ruggiero, G.; Velghe, B.; Wahl, H.

    2017-02-01

    The GigaTracker is a hybrid silicon pixel detector built for the NA62 experiment aiming at measuring the branching fraction of the ultra-rare kaon decay K+ →π+ ν ν bar at the CERN SPS. The detector has to track particles in a beam with a flux reaching 1.3 MHz/mm2 and provide single-hit timing with 200 ps RMS resolution for a total material budget of less than 0.5% X0 per station. The tracker comprises three 60.8 mm×27 mm stations installed in vacuum (∼10-6 mbar) and cooled with liquid C6F14 circulating through micro-channels etched inside a few hundred micron thick silicon plates. Each station is composed of a 200 μm thick silicon sensor read out by 2×5 custom 100 μm thick ASICs, called TDCPix. Each chip contains 40×45 asynchronous pixels, 300 μm×300 μm each and is instrumented with 100 ps bin time-to-digital converters. In order to cope with the high rate, the TDCPix is equipped with four 3.2 Gb/s serialisers sending out the data. We will describe the detector and the results from the 2014 and 2015 NA62 runs.

  9. Added value of sending photograph in diagnosing a medical disease declared at sea: experience of the French Tele-Medical Assistance Service.

    Science.gov (United States)

    Dehours, Emilie; Saccavini, Alexandre; Roucolle, Pierre; Roux, Patrick; Bounes, Vincent

    2017-01-01

    The maritime medical tele-consultation carried out by a doctor from the Toulouse Tele-Medical Assistance Service is currently based on tele-consultation using radiotelegraphy and the complementary transmission of data (photographs, electrocardiogram) via the Internet. In a previous article, we presented the benefits of photograph transmission for trauma management in isolated areas. Through this new series of cases, we wanted to expose the aspect of the medical pathologies and the contribution of sending photographs in their management. Case 1. Myocardial infarction. Case 2. Toxic epidermal necrolysis. Case 3. Tooth abscess. Case 4. Shingles. Case 5. Junctional tachycardia. The tele-transmission of photographs provides a real diagnostic and follow-up tool for patients suffering from medical pathologies. The constant increase in the number of tele-consultations with the exchange of photographs shows its necessity and the interest of the participants in the development of these technologies.

  10. The impact of outmigration of men on fertility and marriage in the migrant-sending states of Mexico, 1995-2000.

    Science.gov (United States)

    White, Kari; Potter, Joseph E

    2013-01-01

    Using the 2000 Mexican Census, we examined whether the level of migration was associated with total fertility and the proportion of women married in 314 municipalities from seven traditional sending states. Across these municipalities, we observe lower fertility in higher-migration areas. Municipalities in the quartile with the highest levels of migration have total fertility more than half a child lower than municipalities in the lowest migration quartile. However, there are no differences in marital fertility by level of migration, indicating that lower proportions of women married account for lower total fertility in high-migration municipalities. In municipal-level regression models, lower sex ratios are associated with a lower proportion of women married, while there is an inverse association between education and marriage. The level of migration also has an independent association with marriage, suggesting that there may be changing ideas surrounding family formation in high-migration areas.

  11. Acetylene diffusion in Na-Y zeolite

    Indian Academy of Sciences (India)

    Study of diffusivity of acetylene adsorbed in Na-Y zeolite by quasi-elastic neutron scattering (QENS) measurements at temperatures of 300, 325 and 350 K is reported. A model in which the acetylene molecules undergo random-walk diffusion characterized by a Gaussian distribution of jump lengths inside zeolite cages ...

  12. Design and implementation of the NaI (Tl)CsI (Na) detectors output signal generator

    CERN Document Server

    Zhou, Xu; Zhao, Jian-Ling; Zhang, Fei; Zhang, Yi-Fei; Li, Zheng-Wei; Zhang, Shuo; Li, Xu-Fang; Lu, Xue-Feng; Xu, Zhen-Ling; Lu, Fang-Jun

    2013-01-01

    We designed and implemented a signal generator that can simulate the output of the NaI (Tl)CsI (Na) detectors pre amplifier onboard the Hard X ray Modulation Telescope (HXMT). Using the development of FPGA (Field Programmable Gate Array) with VHDL language and adding random constituent, we have finally produced the double exponential random pulse signal generator. The statistical distribution of signal amplitude is programmable. The occurrence time intervals of adjacent signals content negative exponential distribution statistically.

  13. Avaliação da dor na histeroscopia diagnóstica por vaginoscopia utilizando-se, como meio de distensão, solução salina à temperatura corporal: Ensaio clínico randomizado Evaluation of pain in diagnostic hysteroscopy by vaginoscopy using normal saline at body temperature as distension medium: A randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Zares Maria Melo Cavalcanti de Almeida

    2008-01-01

    Full Text Available OBJETIVO: comparar a histeroscopia diagnóstica por vaginoscopia com soro fisiológico na temperatura corporal com a técnica tradicional, em relação à dor, satisfação da paciente e exeqüibilidade do procedimento. MÉTODOS: ensaio clínico randomizado, envolvendo 184 mulheres, encaminhadas entre maio e dezembro de 2006, para serem submetidas à histeroscopia diagnóstica. As participantes foram randomizadas para realizar o procedimento pela técnica proposta, com acesso por vaginoscopia, sem espéculo ou pinçamento do colo e utilizando soro fisiológico a 36ºC como meio distensor, ou pela técnica tradicional, utilizando CO2.Em ambas as técnicas, foi utilizada óptica de 2,7 mm. A dor foi avaliada pela escala visual analógica (EVA, durante e a cada cinco minutos após o procedimento. RESULTADOS: a dor, na técnica proposta, teve pontuação média de 1,60 e, na técnica tradicional, de 3,39 (pPURPOSE: to compare diagnostic hysteroscopy through vaginoscopy, using warm saline solution, with traditional technique, regarding to pain, patient satisfaction and feasibility of the procedure. METHODS: randomized clinical trial, involving 184 women, referred for diagnostic hysteroscopy, between May and December of 2006. Participants were randomized to be submitted to hysteroscopy by the proposed technique, which consisted of access through vaginoscopy using normal saline at 36ºC as distension medium, no speculum or cervical grasping, or by the traditional technique with CO2. In both techniques, a 2.7 mm hysteroscope was used. Pain was assessed by the analogical visual scale, during the procedure and every five minutes after it. RESULTS: the mean pain score was 1.60 in the proposed technique and 3.39 in the traditional technique (p<0.01. Lower pain scores were also observed after 5, 10 and 15 minutes (p<0,01 as well as after 20 minutes (p=0.056. In the proposed technique, 82.4% of the procedures were feasible, while, in the traditional technique

  14. Random thoughts

    Science.gov (United States)

    ajansen; kwhitefoot; panteltje1; edprochak; sudhakar, the

    2014-07-01

    In reply to the physicsworld.com news story “How to make a quantum random-number generator from a mobile phone” (16 May, http://ow.ly/xFiYc, see also p5), which describes a way of delivering random numbers by counting the number of photons that impinge on each of the individual pixels in the camera of a Nokia N9 smartphone.

  15. Law of iterated logarithm for NA sequences with non-identical ...

    Indian Academy of Sciences (India)

    There are many results about law of iterated logarithm for independent random variables sequences. ... As for negatively associated (NA) random variables, Joag [2] gave the following defi- nition. DEFINITION [2] ... Recently, some authors focused on the problem of limiting behavior of partial sums of. NA sequences. Su et al ...

  16. An open label, randomized, fixed-dose, crossover study comparing efficacy and safety of sildenafil citrate and saffron (Crocus sativus Linn.) for treating erectile dysfunction in men naïve to treatment.

    Science.gov (United States)

    Safarinejad, M R; Shafiei, N; Safarinejad, S

    2010-01-01

    Saffron (Crocus sativus Linn.) have been perceived by the public as a strong aphrodisiac herbal product. However, studies addressing the potential beneficial effects of saffron on erectile function (EF) in men with ED are lacking. Our aim was to evaluate the efficacy and safety of saffron administration on EF in men with ED. After a 4-week baseline assessment, 346 men with ED (mean age 46.6+/-8.4 years) were randomized to receive on-demand sildenafil for 12 weeks followed by 30 mg saffron twice daily for another 12 weeks or vice versa, separated by a 2-week washout period. To determine the type of ED, penile color duplex Doppler ultrasonography before and after intracavernosal injection with 20 microg prostaglandin E(1), pudendal nerve conduction tests and impaired sensory-evoked potential studies were performed. Subjects were assessed with an International Index of Erectile Function (IIEF) questionnaire, Sexual Encounter Profile (SEP) diary questions, patient and partner versions of the Erectile Dysfunction Inventory of Treatment Satisfaction (EDITS) questionnaire and the Global Efficacy Question (GEQ) 'Has the medication you have been taking improved your erections?' No significant improvements were observed with regard to the IIEF sexual function domains, SEP questions and EDITS scores with saffron administration. The mean changes from baseline values in IIEF-EF domain were +87.6% and +9.8% in sildenafil and placebo groups, respectively (P=0.08). We did not observe any improvement in 15 individual IIEF questions in patients while taking saffron. Treatment satisfaction as assessed by partner versions of EDITS was found to be very low in saffron patients (72.4 vs 25.4, P=0.001). Mean per patient 'yes' responses to GEQ was 91.2 and 4.2% for sildenafil and saffron, respectively (P=0.0001). These findings do not support a beneficial effect of saffron administration in men with ED.

  17. The NA62 GigaTracker

    CERN Document Server

    Aglieri Rinella, G; Arcidiacono, R; Biino, C; Bonacini, S; Ceccucci, A; Chiozzi, S; Cortina Gil, E; Cotta Ramusino, A; Degrange, J; Fiorini, M; Gamberini, E; Gianoli, A; Kaplon, J; Kluge, A; Mapelli, A; Marchetto, F; Minucci, E; Morel, M; Noël, J; Noy, M; Perktold, L; Perrin-Terrin, M; Petagna, P; Petrucci, F; Poltorak, K; Romagnoli, G; Ruggiero, G; Velghe, B; Wahl, H

    2016-01-01

    The GigaTracker is a hybrid silicon pixel detector built for the NA62 experiment aiming at measuring the branching fraction of the ultra-rare kaon decay K+→π+νν¯ at the CERN SPS. The detector has to track particles in a beam with a flux reaching 1.3 MHz/mm2 and provide single-hit timing with 200 ps RMS resolution for a total material budget of less than 0.5% X0 per station. The tracker comprises three 60.8 mm×27 mm stations installed in vacuum (∼10$^{−6}$mbar) and cooled with liquid C6F14 circulating through micro-channels etched inside a few hundred micron thick silicon plates. Each station is composed of a 200 μm thick silicon sensor read out by 2×5 custom 100 μm thick ASICs, called TDCPix. Each chip contains 40×45 asynchronous pixels, 300 μm×300 μm each and is instrumented with 100 ps bin time-to-digital converters. In order to cope with the high rate, the TDCPix is equipped with four 3.2 Gb/s serialisers sending out the data. We will describe the detector and the results from the 2014 an...

  18. Universal randomness

    Energy Technology Data Exchange (ETDEWEB)

    Dotsenko, Viktor S [Landau Institute for Theoretical Physics, Russian Academy of Sciences, Moscow (Russian Federation)

    2011-03-31

    In the last two decades, it has been established that a single universal probability distribution function, known as the Tracy-Widom (TW) distribution, in many cases provides a macroscopic-level description of the statistical properties of microscopically different systems, including both purely mathematical ones, such as increasing subsequences in random permutations, and quite physical ones, such as directed polymers in random media or polynuclear crystal growth. In the first part of this review, we use a number of models to examine this phenomenon at a simple qualitative level and then consider the exact solution for one-dimensional directed polymers in a random environment, showing that free energy fluctuations in such a system are described by the universal TW distribution. The second part provides detailed appendix material containing the necessary mathematical background for the first part. (reviews of topical problems)

  19. Testing Na+ in blood

    OpenAIRE

    Lava, Sebastiano A.G.; Bianchetti, Mario G.; Milani, Gregorio P.

    2016-01-01

    Abstract Both direct potentiometry and indirect potentiometry are currently used for Na+ testing in blood. These measurement techniques show good agreement as long as protein and lipid concentrations in blood remain normal. In severely ill patients, indirect potentiometry commonly leads to relevant errors in Na+ estimation: 25% of specimens show a disagreement between direct and indirect potentiometry, which is ?4 mmol/L (mostly spuriously elevated Na+ level due to low circulating albumin con...

  20. Random triangles

    OpenAIRE

    Matula, Dominik

    2013-01-01

    The author summarizes some previous results concerning random triangles. He describes the Gaussian triangle and random triangles whose vertices lie in a unit n-dimensional ball, in a rectangle or in a general bounded convex set. In the second part, the author deals with an inscribed triangle in a triangle - let ABC be an equilateral triangle and let M, N, O be three points, each laying on one side of the ABC. We call MNO inscribed triangle (in an equi- laterral triangle). The median triangle ...

  1. Random matrices

    CERN Document Server

    Mehta, Madan Lal

    1990-01-01

    Since the publication of Random Matrices (Academic Press, 1967) so many new results have emerged both in theory and in applications, that this edition is almost completely revised to reflect the developments. For example, the theory of matrices with quaternion elements was developed to compute certain multiple integrals, and the inverse scattering theory was used to derive asymptotic results. The discovery of Selberg's 1944 paper on a multiple integral also gave rise to hundreds of recent publications. This book presents a coherent and detailed analytical treatment of random matrices, leading

  2. VPLIV AMBROZIJE NA ZDRAVJE

    OpenAIRE

    Tramšek, Dejan

    2015-01-01

    Izhodišča: V raziskavi smo se osredotočili na opis različnih vrst ambrozije. Opisali smo tudi rastline, ki so v veliki meri podobne ambroziji. Ob vsem tem pa seveda vpliv ambrozije na zdravje ljudi, predvsem alergij. Predstavili smo posamezne alergije, opisali način preprečevanja in zdravljenja le-teh in simptome, ki alergije spremljajo. Za omejitev in zmanjšanje pojava alergij na ambrozijo pa je to rastlino potrebno odstraniti oz. zamejiti. Odločili smo se, da v diplomskem delu predstavimo ...

  3. A Multi-User Game-Theoretical Multipath Routing Protocol to Send Video-Warning Messages over Mobile Ad Hoc Networks

    Directory of Open Access Journals (Sweden)

    Ahmad Mohamad Mezher

    2015-04-01

    Full Text Available The prevention of accidents is one of the most important goals of ad hoc networks in smart cities. When an accident happens, dynamic sensors (e.g., citizens with smart phones or tablets, smart vehicles and buses, etc. could shoot a video clip of the accident and send it through the ad hoc network. With a video message, the level of seriousness of the accident could be much better evaluated by the authorities (e.g., health care units, police and ambulance drivers rather than with just a simple text message. Besides, other citizens would be rapidly aware of the incident. In this way, smart dynamic sensors could participate in reporting a situation in the city using the ad hoc network so it would be possible to have a quick reaction warning citizens and emergency units. The deployment of an efficient routing protocol to manage video-warning messages in mobile Ad hoc Networks (MANETs has important benefits by allowing a fast warning of the incident, which potentially can save lives. To contribute with this goal, we propose a multipath routing protocol to provide video-warning messages in MANETs using a novel game-theoretical approach. As a base for our work, we start from our previous work, where a 2-players game-theoretical routing protocol was proposed to provide video-streaming services over MANETs. In this article, we further generalize the analysis made for a general number of N players in the MANET. Simulations have been carried out to show the benefits of our proposal, taking into account the mobility of the nodes and the presence of interfering traffic. Finally, we also have tested our approach in a vehicular ad hoc network as an incipient start point to develop a novel proposal specifically designed for VANETs.

  4. A Multi-User Game-Theoretical Multipath Routing Protocol to Send Video-Warning Messages over Mobile Ad Hoc Networks

    Science.gov (United States)

    Mezher, Ahmad Mohamad; Igartua, Mónica Aguilar; de la Cruz Llopis, Luis J.; Segarra, Esteve Pallarès; Tripp-Barba, Carolina; Urquiza-Aguiar, Luis; Forné, Jordi; Gargallo, Emilio Sanvicente

    2015-01-01

    The prevention of accidents is one of the most important goals of ad hoc networks in smart cities. When an accident happens, dynamic sensors (e.g., citizens with smart phones or tablets, smart vehicles and buses, etc.) could shoot a video clip of the accident and send it through the ad hoc network. With a video message, the level of seriousness of the accident could be much better evaluated by the authorities (e.g., health care units, police and ambulance drivers) rather than with just a simple text message. Besides, other citizens would be rapidly aware of the incident. In this way, smart dynamic sensors could participate in reporting a situation in the city using the ad hoc network so it would be possible to have a quick reaction warning citizens and emergency units. The deployment of an efficient routing protocol to manage video-warning messages in mobile Ad hoc Networks (MANETs) has important benefits by allowing a fast warning of the incident, which potentially can save lives. To contribute with this goal, we propose a multipath routing protocol to provide video-warning messages in MANETs using a novel game-theoretical approach. As a base for our work, we start from our previous work, where a 2-players game-theoretical routing protocol was proposed to provide video-streaming services over MANETs. In this article, we further generalize the analysis made for a general number of N players in the MANET. Simulations have been carried out to show the benefits of our proposal, taking into account the mobility of the nodes and the presence of interfering traffic.Finally, we also have tested our approach in a vehicular ad hoc network as an incipient start point to develop a novel proposal specifically designed for VANETs. PMID:25897496

  5. Avaliação da persistência na lactação da raça Guzerá, utilizando modelos de regressão aleatória Evaluation of lactation persistency of Guzerat cows using random regression models

    Directory of Open Access Journals (Sweden)

    L.S. Freitas

    2010-04-01

    Full Text Available Estimaram-se a herdabilidade e as correlações genéticas e de ambiente permanente entre seis medidas de persistência da lactação de vacas da raça Guzerá, utilizando modelo de regressão aleatória. Foram considerados 8276 registros de produção de leite no dia do controle, na primeira lactação, de 1021 vacas. A regressão aleatória foi calculada pela função logarítmica de Ali e Schaeffer e pelo polinômio de Legendre, obtendo-se os coeficientes para os efeitos fixos, genético aditivo e de ambiente permanente. A função que mais se adequou aos dados foi a de Ali e Schaeffer, mas apresentou problemas de convergência. Os resultados evidenciaram que a persistência é uma característica com herdabilidade de valor moderado e de baixa correlação com o valor genético para produção de leite aos 305 dias, indicando a possibilidade de se obter resposta à seleção para mudança na curva de lactação sem afetar negativamente a produção total de leite na lactação. A medida de persistência que calcula a diferença de produção de leite entre as fases intermediária e inicial da lactação apresentou alta correlação com a produção aos 305 dias.The heritability and the genetic and permanent environment correlations were estimated among six different measures of persistency in the lactation of Guzerat cow, using the Random Regression Model. A total of 8,403 records from 1,034 first lactation cows were evaluated. The Random Regression Model was calculated by the logarithmic function of Ali and Schaeffer and Legendre polynomials to get coefficients for fixed, additive genetic and permanent environment effects. Ali and Schaeffer was the function that better fit to the data, but it had convergence problems. The results showed that persistence is a trait with moderate heritability, and low correlation with genetic value for 305-d milk production which allows to select animals in order to alter the format of the curve of production

  6. Uso de modelos de regressão aleatória para descrever a variação genética da produção de leite na raça Holandesa Random regressions models to describe the genetic variation of milk yield in Holstein breed

    Directory of Open Access Journals (Sweden)

    Cláudio Vieira de Araújo

    2006-06-01

    Full Text Available Registros de produção de leite de 68.523 controles leiteiros de 8.536 vacas da raça Holandesa, com parições nos anos de 1996 a 2001, foram utilizados na comparação entre modelos de regressão aleatória para estimação de componentes de variância. Os registros de controle leiteiro foram analisados como características múltiplas, considerando cada controle uma característica distinta. Os mesmos registros de controle leiteiro foram analisados como dados longitudinais, por meio de modelos de regressão aleatória, que diferiram entre si pela função utilizada para descrever a trajetória da curva de lactação dos animais. As funções utilizadas foram a exponencial de Wilmink, a função de Ali e Schaeffer e os polinômios de Legendre de segundo e quarto graus. A comparação entre modelos foi realizada com base nos seguintes critérios: estimativas de componentes de variância, obtidas no modelo multicaractístico e por regressão aleatória; valores da variância residual; e valores do logaritmo da função de verossimilhança. As estimativas de herdabilidade obtidas por meio dos modelos de características múltiplas variaram de 0,110 a 0,244. Para os modelos de regressão aleatória, esses valores oscilaram de 0,127 a 0,301, observando-se as maiores estimativas nos modelos com maior número de parâmetros. Verificou-se que os modelos de regressão aleatória que utilizaram os polinômios de Legendre descreveram melhor a variação genética da produção de leite.Data comprising 68,523 test day milk yield of 8,536 cows of the Holstein breed, calving from 1996 to 2001, were used to compare random regression models, for estimating variance components. Test day records (TD were analyzed as multiple traits, considering each TD as a different trait. The test day records were analyzed as longitudinal traits by different random regression models regarding the function used to describe the trajectory of the lactation curve of the animals

  7. Random walks in a random environment

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

    Abstract. Random walks as well as diffusions in random media are considered. Methods are developed that allow one to establish large deviation results for both the 'quenched' and the 'averaged' case. Keywords. Large deviations; random walks in a random environment. 1. Introduction. A random walk on Zd is a stochastic ...

  8. At NA2

    CERN Multimedia

    1977-01-01

    One of the NA2 calorimeter sections is moved in. The NA2 calorimeter was divided in two halves, to the left and the right of the beam, each half consisting of sheets of passive high Z material interleaved with blades of plastic scintillators. The photo shows on the right, the upstream 'electron' module with eleven lead plates for a total radiation length of 20.

  9. Random tensors

    CERN Document Server

    Gurau, Razvan

    2017-01-01

    Written by the creator of the modern theory of random tensors, this book is the first self-contained introductory text to this rapidly developing theory. Starting from notions familiar to the average researcher or PhD student in mathematical or theoretical physics, the book presents in detail the theory and its applications to physics. The recent detections of the Higgs boson at the LHC and gravitational waves at LIGO mark new milestones in Physics confirming long standing predictions of Quantum Field Theory and General Relativity. These two experimental results only reinforce today the need to find an underlying common framework of the two: the elusive theory of Quantum Gravity. Over the past thirty years, several alternatives have been proposed as theories of Quantum Gravity, chief among them String Theory. While these theories are yet to be tested experimentally, key lessons have already been learned. Whatever the theory of Quantum Gravity may be, it must incorporate random geometry in one form or another....

  10. Random functions and turbulence

    CERN Document Server

    Panchev, S

    1971-01-01

    International Series of Monographs in Natural Philosophy, Volume 32: Random Functions and Turbulence focuses on the use of random functions as mathematical methods. The manuscript first offers information on the elements of the theory of random functions. Topics include determination of statistical moments by characteristic functions; functional transformations of random variables; multidimensional random variables with spherical symmetry; and random variables and distribution functions. The book then discusses random processes and random fields, including stationarity and ergodicity of random

  11. Immediate effects of TENS and cryotherapy in the reflex excitability and voluntary activity in hemiparetic subjects: a randomized crossover trial Efeitos imediatos da TENS e crioterapia na excitabilidade reflexa e atividade voluntária de sujeitos hemiparéticos: um estudo controlado aleatorizado cruzado

    Directory of Open Access Journals (Sweden)

    Fábio L. Martins

    2012-08-01

    Full Text Available BACKGROUND: The disorder of reflex and motor function in patients affected by stroke causes negative impact on the performance of movement patterns and affects the functional activities. OBJECTIVES: To investigate the immediate effects of transcutaneous electrical nerve stimulation (TENS and cryotherapy interventions on the spinal reflex excitability and in the voluntary electromyography (EMG activity in people with chronic stroke. METHOD: Randomized crossover trial. The maximum H-reflex (Hmax, the H-reflex latency and the maximum motor response (Mmax of the soleus muscle and also the EMG of the tibialis muscle where evaluated before and after the application of TENS, cryotherapy and control conditions. RESULTS: The Hmax/Mmax ratio was statistically significant higher (p=0.0245 and the H-reflex latency was statistically significant lower (p=0.0375 in the soleus muscle of the affected limb. The EMG amplitude of the tibialis anterior was reduced in the compromised limb (pCONTEXTUALIZAÇÃO: O distúrbio da função motora e reflexa em pacientes acometidos por acidente vascular encefálico (AVE causa impactos negativos na realização de padrões motores, comprometendo as atividades funcionais. OBJETIVOS: Investigar os efeitos imediatos da estimulação elétrica nervosa transcutânea (TENS e da crioterapia na excitabilidade reflexa e na atividade voluntária de sujeitos vítimas de AVE. MÉTODO: Estudo Crossover. O reflexo H máximo (Hmáx, a latência do reflexo H e a resposta motora máxima (Mmáx do músculo solear e a eletromiografia (EMG do músculo tibial anterior foram avaliados antes e após a aplicação de TENS, crioterapia e em condições de controle. RESULTADOS: A razão Hmáx/Mmáx estava significativamente aumentada (p=0,0245 e a latência do reflexo H significativamente diminuída (p=0,0375 no músculo solear do membro afetado. A amplitude do sinal EMG do músculo estava significativamente reduzida no membro comprometido (p<0

  12. Random fixed points and random differential inclusions

    Directory of Open Access Journals (Sweden)

    Nikolaos S. Papageorgiou

    1988-01-01

    Full Text Available In this paper, first, we study random best approximations to random sets, using fixed point techniques, obtaining this way stochastic analogues of earlier deterministic results by Browder-Petryshyn, KyFan and Reich. Then we prove two fixed point theorems for random multifunctions with stochastic domain that satisfy certain tangential conditions. Finally we consider a random differential inclusion with upper semicontinuous orientor field and establish the existence of random solutions.

  13. Gêneros orais na escola

    OpenAIRE

    Teixeira,Lucia

    2012-01-01

    O artigo analisa a utilização da noção de gênero na escola fundamental, detendo-se sobre o ensino dos gêneros orais. Apresenta postulados teóricos de Bakhtin e incorpora a contribuição da semiótica discursiva e as sugestões metodológicas da pedagogia de ensino de línguas desenvolvida na Universidade de Genebra. Em seguida, propõe exemplo prático de aplicação do conceito ao desenvolvimento da expressão oral em sala de aula.

  14. Law of iterated logarithm for NA sequences with non-identical ...

    Indian Academy of Sciences (India)

    Based on a law of the iterated logarithm for independent random variables sequences, an iterated logarithm theorem for NA sequences with non-identical distributions is obtained. The proof is based on a Kolmogrov-type exponential inequality.

  15. At NA5

    CERN Multimedia

    1978-01-01

    The NA5 experiment is shown at the start of the setting up in beam H2 of hall EHN1. It was designed by the Bari- Cracow-Liverpool-Munich (MPI) Collaboration to study hard hadron-hadron collisions with a streamer chamber vertex spectrometer and a calorimeter trigger. The beam from target T2 enters from the left. E

  16. Riso na epilepsia

    Directory of Open Access Journals (Sweden)

    Edymar Jardim

    1967-06-01

    Full Text Available São estudados três casos de síndrome convulsiva temporal, com manifestações concomitantes de riso na sua fase inicial. As características principais foram a imotivação e á incoercibilidade do riso. Esses sintomas desapareceram com o uso de anticonvulsivantes.

  17. Biotecnologia na agricultura

    Directory of Open Access Journals (Sweden)

    Helaine Carrer

    2010-01-01

    Full Text Available A expectativa de o crescimento populacional atingir 9 bilhões de habitantes em 2050 em adição às questões da sustentabilidade e do aquecimento global nos desafiam a aumentar a oferta de alimentos. Uma metodologia alternativa que contribua para a redução do impacto desse cenário envolve a biotecnologia, que, nas últimas décadas, trouxe marcantes oportunidades tecnológicas na agricultura, resultando em relevante desenvolvimento na obtenção de novas variedades de plantas, na melhoria da qualidade de diversos alimentos e atualmente também na bioenergia. As técnicas biotecnológicas envolvendo os marcadores moleculares, a genômica e a transformação genética estão transformando a agricultura e são discutidas neste artigo.The expected population growth to reach 9 billion by 2050 in addition to issues of sustainability and global warming challenges us to increase the supply of food. An alternative approach to help reducing the impact of this scenario involves biotechnology which in recent decades has brought remarkable technological opportunities in the agriculture that resulted in relevant development in obtaining new plant varieties, improved quality of different foods, and now also in bioenergy. The biotechnology techniques involving molecular markers, genomics and genetic transformation are transforming agriculture and will be discussed in this article.

  18. At NA3

    CERN Multimedia

    1977-01-01

    The NA3 experiment was setup in beam H8 in the Hall EHN1 by the CERN-College de France-Orsay-Palaiseau-Saclay Collaboration to study the hadronic production of high pT leptons and hadrons. The photo shows in the background (centre) the electromagnetic calorimeter.

  19. [The remittances in U.S. dollars that Mexican migrants send home from the United States (a study based on data from the Survey of Migration in the Northern Frontier Region of Mexico)].

    Science.gov (United States)

    Corona Vasquez, R

    1998-01-01

    The difficulties in obtaining reliable data on remittances to Mexico by Mexican immigrants in the United States are first outlined. An analysis of such remittances is then attempted using data from a recent survey, the Encuesta sobre Migracion en la Frontera Norte. Data from this survey are used to analyze several aspects of remittances "such as the direct determination of the amount of the remittances and the identification of the immigrants that send them according to their social and demographic features, and the location of Mexican zones where the remittances arrive, [and] the variations in the amount and frequency of the remittances among the different groups of immigrants." (EXCERPT)

  20. Impacto dos exercícios na capacidade funcional e dor em pacientes com osteoartrite de joelhos: ensaio clínico randomizado Impact of exercise on the functional capacity and pain of patients with knee osteoarthritis: a randomized clinical trial

    Directory of Open Access Journals (Sweden)

    Aline Mizusaki Imoto de Oliveira

    2012-12-01

    Full Text Available INTRODUÇÃO: A fraqueza muscular, especialmente do quadríceps, é uma das principais repercussões osteomusculares da osteoartrite de joelho, e os exercícios são considerados uma das principais intervenções no tratamento conservador da doença. OBJETIVO: Avaliar o efeito do fortalecimento do quadríceps femural na capacidade funcional e nos sintomas relacionados à osteoartrite de joelho utilizando o teste Timed Up and Go (TUG, o questionário Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC e o Índice de Lequesne. MÉTODOS: Foram randomizados 100 pacientes, divididos em dois grupos: 1 Grupo Exercício (n = 50, o qual incluiu bicicleta estacionária, alongamento dos músculos isquiotibiais e fortalecimento do músculo quadríceps, e 2 Grupo Orientação (n = 50, que recebeu um manual de orientações a fim de descrever a osteoartrite de joelho e instruir os pacientes a como ajustar o dia a dia de acordo com os sintomas. Os pacientes foram informados sobre os sinais e sintomas da doença e os cuidados durante as atividades de vida diária. O manual não incluiu orientação de exercícios. RESULTADOS: O Grupo Exercício apresentou melhora estatisticamente significante no teste TUG, nos aspectos dor, função e rigidez do questionário WOMAC e no índice Lequesne, quando comparado ao Grupo Orientação. CONCLUSÃO: Exercícios para fortalecimento do quadríceps com duração de oito semanas são efetivos na melhora de dor, função e rigidez em pacientes com osteoartrite de joelho.BACKGROUND: Muscle weakness, especially of the quadriceps muscle, is one of the major musculoskeletal effects of knee osteoarthritis. Exercises are considered one of the main interventions in the conservative treatment of those patients. OBJECTIVE: To assess the effectiveness of quadriceps strengthening exercises on functional capacity and symptoms related of knee osteoarthritis by use of the Timed Up and Go test (TUG, the Western Ontario and

  1. Comparison of two methods of femoral tunnel preparation in single-bundle anterior cruciate ligament reconstruction: a prospective randomized study Comparação entre dois métodos de preparação de túnel femoral na reconstrução do ligamento cruzado anterior em feixe único: estudo prospectivo randomizado

    Directory of Open Access Journals (Sweden)

    Qiang Zhang

    2012-08-01

    Full Text Available PURPOSE: To prospectively compare therapeutic effect of femoral tunnel preparation through the tibial tunnel and the anteromedial (AM portal in single-bundle anterior cruciate ligament (ACL reconstruction. METHODS: Between June 2008 and October 2010, 76 patients underwent single-bundle ACL reconstruction by autogenous grafting of semitendinosus and gracilis tendon. All cases were randomly divided into two groups according to the method of femoral tunnel preparation: transtibial (TT group (n=38 and anteromedial (AM group (n=38. Lysholm knee score and the KT-1000 anterior laxity at 30° of pre-and post-operation were assessed for two groups. RESULTS: Sixty-five patients (TT group, 34; AM group, 31 were followed up for more than 12 months, with a follow-up rate of 86%. The Lysholm knee score and the KT-1000 anterior laxity 12 months after operation were significantly better than before reconstruction. The Lysholm knee score and the KT-1000 anterior laxity were not significantly different between the TT and AM groups after operation. CONCLUSION: Femoral tunnel preparation through tibial tunnel or the anteromedial portal in single-bundle anterior cruciate ligament reconstruction shows same therapeutic effects.OBJETIVO: Comparar prospectivamente o efeito terapêutico da preparação do túnel femoral através do túnel tibial (TT ou da porta ântero-medial(AM na reconstrução do ligamento cruzado anterior(LCA em feixe único. MÉTODOS: Entre junho de 2008 e outubro de 2010, 76 pacientes foram submetidos à reconstrução do LCA em feixe único pelo enxerto autógeno de tendão semitendíneo egrácil.Todos os casos foram divididos aleatoriamente em dois grupos de acordo como método de preparação do túnel femoral: grupo transtibial (TT (n=38 e grupo ântero-medial (AM (n=38. Foi usado o escore Lysholm para joelho. O relaxamento anterior do joelho a 30° sob força tênsil de 133,32N foi determinado com o medidor KT-1000 no pré e no p

  2. Effect of enamel matrix proteins on the treatment of intrabony defects: a split-mouth randomized controlled trial study O efeito da proteína da matriz do esmalte no tratamento de defeitos infra-ósseos: um estudo clínico controlado randomizado boca-dividida

    Directory of Open Access Journals (Sweden)

    Daniela Chambrone

    2007-09-01

    Full Text Available The objective of this split-mouth, double-blind, randomized controlled trial was to compare the clinical effect of treatment of 2- or 3-wall intrabony defects with open flap debridement (OFD combined or not with enamel matrix proteins (EMP. Thirteen volunteers were selected with one pair of or more intrabony defects and probing pocket depth (PPD > 5 mm. All individuals received instructions regarding oral hygiene and were submitted to scaling and root planing. Each participant received the two treatment modalities: test sites were treated with OFD and EMP, and control sites received only OFD. After 6 months, a significant reduction was observed in PPD for the EMP group (from 6.42 ± 1.08 mm to 2.67 ± 1.15 mm and for the OFD group (from 6.08 ± 1.00 mm to 2.00 ± 0.95 mm (p O objetivo deste estudo clínico controlado, randomizado, duplo-cego, tipo boca-dividida foi comparar o efeito clínico do tratamento de defeitos infra-ósseos de 2 ou 3 paredes com retalho de espessura total (RET associado ou não com a proteína da matriz do esmalte (PME. Treze voluntários com 1 par ou mais de defeitos infra-ósseos foram selecionados com profundidade clínica de sondagem (PCS > 5 mm. Todos receberam instruções de higiene bucal, raspagem e alisamento radicular. Cada participante recebeu os dois tipos de tratamento: o lado teste foi tratado com RET e PME, e o lado controle recebeu somente RET. Após 6 meses, foi observada uma redução significante na PCS para o grupo PME (de 6,42 ± 1,08 mm para 2,67 ± 1,15 mm e para o grupo RET (de 6,08 ± 1,00 mm para 2,00 ± 0,95 mm (p < 0,0001, mas não houve diferença significante entre os grupos (p = 0,13. Um ganho significante de nível clínico de inserção relativo (NCIR foi observado em ambos os grupos (PME: de 13,42 ± 1,88 mm para 10,75 ± 2,26 mm, p < 0,001; RET: de 12,42 ± 1,98 mm para 10,58 ± 2,23 mm, p = 0,013, mas não houve diferença significante entre os grupos (p = 0,85. A retração gengival

  3. O JORNALISTA NA PESQUISA E NA ARTE

    Directory of Open Access Journals (Sweden)

    Beatriz Marocco

    2013-06-01

    Full Text Available O jornalista tem sido objeto das artes e das ciências. Nesta incisão no tema do painel “Configurações e perspectivas da pesquisa em jornalismo no Brasil em diálogo com os estudos latinoamericanos em jornalismo”, realizado no Encontro Nacional da Sociedade Brasileira de Pesquisadores em Jornalismo/SBPJor (Curitiba, 10/11/2012, reconheci que o âmbito acadêmico projeta dois tipos de ação: em rede de pesquisadores de diferentes países e regiões do mundo, com participação de países da América Latina, na pesquisa colaborativa e em projetos de investigação com outras bases de colaboração. Ambas as modalidades dialogam com a produção do cinema e da literatura – que visibiliza a grande potência do profissional para tramas e tensões. 

  4. Efeito do azul de metileno na resposta inflamatória e hemodinâmica em pacientes submetidos à cirurgia de revascularização miocárdica com circulação extracorpórea Methylene blue use in coronary artery bypass surgery: a prospective randomized study of the hemodynamic and inflammatory responses

    Directory of Open Access Journals (Sweden)

    Nilzo Augusto Mendes Ribeiro

    2004-03-01

    Full Text Available OBJETIVO: Estudar em pacientes submetidos à cirurgia de revascularização miocárdica com circulação extracorpórea os efeitos da infusão de azul de metileno na reação inflamatória sistêmica e nas condições hemodinâmica e laboratorial. MÉTODO: Foram estudados 60 pacientes randomizados em dois grupos, utilizando-se a infusão de azul de metileno em um dos dois grupos. Amostras de sangue foram colhidas antes da indução anestésica, 3, 6, 24 e 48 horas após o término da circulação extracorpórea para dosagens dos marcadores de inflamação (IL-1b, IL-6, IL-8, IL-10, IL-12p40 e TNFa, NO, gasometria e outras dosagens de rotina. RESULTADOS: O grupo que utilizou azul de metileno mostrou, em diferentes momentos das coletas, maior resistência vascular sistêmica, menor concentração de TNFa, menor número de leucócitos e neutrófilos e menor nível de óxido nítrico. Não ocorreram efeitos adversos importantes. CONCLUSÕES: A infusão de azul de metileno não evidenciou alterações clínicas ou pulmonares adversas, mostrando uma tendência menor à resposta inflamatória sistêmica, menores níveis de óxido nítrico e melhor estabilidade hemodinâmica.OBJECTIVE: To assess the effects of methylene blue infusion on on-pump coronary artery bypass patients in relation to hemodynamic, laboratorial and systemic inflammatory response. METHOD: Sixty patients were randomized in two groups. Methylene blue was infused in one group. Blood samples were collected before the anesthesia and, 3, 6, 24 and 48 hours after the end of the extracoporeal circulation to determine the IL-1b, IL-6, IL-8, IL-10, IL-12p40, TNFa and nitric oxide levels and perform gasometry and other routine tests. RESULTS: In the methylene group we observed at different stages, higher systemic vascular resistance, lower TNFa concentrations, fewer leukocytes and neutrophils as well as lower level of nitric oxide. No adverse effects were evidenced. CONCLUSIONS: Methylene blue

  5. Frame-Based Random Access with Interference Cancellation across Frames for Massive Machine Type Communications

    Directory of Open Access Journals (Sweden)

    Minjoong Rim

    2017-01-01

    Full Text Available One of the main requirements for next generation mobile or wireless communication systems is to effectively support a large number of machine type communication devices for Internet of things applications. In order to improve the random access capability in frame-based slotted Aloha environments, coded random access techniques have been proposed, in which multiple copies of a packet are transmitted per frame and the copies are cancelled out from the received signal if any single copy is successfully received. They, however, may increase the transmission power by sending multiple copies per frame. Above all, for systems with a small number of slots per frame, they may not be able to improve the performance by readily reaching a congested state. This paper proposes a new frame-based random access scheme, which sends at most one copy of a packet per frame but uses interference cancellation to improve the performance. If a successfully received packet is a retransmitted one, the previously transmitted signals for the packet can be cancelled out from the received signals for trying to decode other received packets. The proposed scheme has different characteristics than coded random access schemes and can be also combined with them to further improve the performance.

  6. Romanskoe vlijanie na staroserbskij sintaksis

    OpenAIRE

    Pavlović Slobodan

    2010-01-01

    V nastojaščej rabote rassmatrivajutsja kontekstual'nye aspekty vlijanija romanskogo substrata i adstrata na staroserbskij sintaksis. Na sintaksis staroserbskogo razgovornogo jazyka mogli vlijat' vlašskie, dalmatinskie i ital'janskie dialekty. Na sintaksis staroserbskoj pis'mennosti (krome serbsko-slavjanskogo jazyka i romanskogo substrata) okazali vlijanie latinskij i ital'janskij jazyki, poskol'ku na territorii rasprostranenija serbskogo jazyka peresekalis' dve velikie kul'tury: Pax Sl...

  7. Preparing for NA4

    CERN Multimedia

    CERN PhotoLab

    1977-01-01

    Here, in one of the EF workshop, Albert Duchêne works on a pretty piece of mechanics. A few others await to be attended on the left. There are indications that the pipes were meant to house the carbon target (subdivided in eight sections) to be installed inside the toroid magnet of the NA4 experiment. The external strips were designed to possibly correct the magnetic field (???).

  8. Hidroma subdural na fossa posterior

    Directory of Open Access Journals (Sweden)

    José Carlos Vasques

    1970-03-01

    Full Text Available Os autores relatam um caso de hidroma subdural na fossa craniana posterior conseqüente a traumatismo na região occipital. O paciente foi operado com pleno sucesso. A raridade da localização de hidroma na fossa posterior é salientada, sendo discutidos os possíveis mecanismos etio-patogênicos.

  9. Random Shift and XOR of Unequal-sized Packets (RaSOR) to Shave off Transmission Overhead

    DEFF Research Database (Denmark)

    Taghouti, Maroua; Roetter, Daniel Enrique Lucani; Fitzek, Frank Hanns Paul

    2017-01-01

    We propose the design of a novel coding scheme of unequal-sized packets. Unlike the conventional wisdom that consists of brute-force zero-padding in Random Linear Network Coding (RLNC), we exploit this heterogeneity to shave off this trailing overhead and transmit considerably less coded packets....... distributions as well as the random choice of the shifts only. Our simulation results performed on a state-of-the-art video trace show that in average we need to send only the third of what RLNC for higher finite fields needs to transmit before decoding....

  10. The CERES / NA45 experiment

    CERN Multimedia

    Laurent Guiraud

    2000-01-01

    Ceres is one of the second generation heavy ion experiments at CERN's SPS. It is dedicated to the study of electron-positron pairs in relativistic nuclear collisions. NA45 is one of the seven experiments (NA44, NA45, NA49, NA50, NA52, WA97/NA57 and WA98) involved in CERN's Heavy Ion programme which provided evidence for the existence of a new state of matter, the quark-gluon plasma. In this state, quarks, instead of being bound up into more complex particles such as protons and neutrons, are liberated and roam freely. Theory predicts that this state must have existed at about 10 microseconds after the Big Bang, before the formation of matter as we know it today.

  11. na Perua

    Directory of Open Access Journals (Sweden)

    Jorge Carvalho

    1989-01-01

    Full Text Available Antes de se caracterizar como tentativa de ensaio ou de análise a qualquer coisa, o presente artigo tem, antes de mais nada, a pretensão de se constituir uma provocação ao debate acerca da questão do esporte na escola. A provocação parte basicamente do relato da minha experiência pessoal como Secretário da Educação do Município de Aracaju, cargo que exerci no período de 1º de janeiro de 1986 a 27 de janeiro de 1987.

  12. Random broadcast on random geometric graphs

    Energy Technology Data Exchange (ETDEWEB)

    Bradonjic, Milan [Los Alamos National Laboratory; Elsasser, Robert [UNIV OF PADERBORN; Friedrich, Tobias [ICSI/BERKELEY; Sauerwald, Tomas [ICSI/BERKELEY

    2009-01-01

    In this work, we consider the random broadcast time on random geometric graphs (RGGs). The classic random broadcast model, also known as push algorithm, is defined as: starting with one informed node, in each succeeding round every informed node chooses one of its neighbors uniformly at random and informs it. We consider the random broadcast time on RGGs, when with high probability: (i) RGG is connected, (ii) when there exists the giant component in RGG. We show that the random broadcast time is bounded by {Omicron}({radical} n + diam(component)), where diam(component) is a diameter of the entire graph, or the giant component, for the regimes (i), or (ii), respectively. In other words, for both regimes, we derive the broadcast time to be {Theta}(diam(G)), which is asymptotically optimal.

  13. Comprometimento pulmonar na leptospirose

    Directory of Open Access Journals (Sweden)

    Jorge Eduardo Manhães de Carvalho

    1992-03-01

    Full Text Available Em 23 pacientes com leptospirose apresentando comprometimento pulmonar, internados no Hospital Universitário Antônio Pedro da XJFF, Niterói, hemoptise e hemoptóicos foram observados em 21,7% e 30,4%, respectivajnente. Gasometria arterial revelou hipoxemia e hipocapnia na maioria dos casos. Radiografia de tórax em 15 pacientes mostrou comprometimento alveolar em 60%, comprometimento intersticial-reticular em 6%, padrão misto (alveolar e intersticial em20%e ausência de alterações radiológicas em 14%. A necrópsiade 13 pacientes mostrou edema, congestão e hemorragia nos pulmões em 100% dos casos. A hemorragia foi focal em 46% e difusa em 54% dos casos. Houve formação de membrana hialina em 30% e trombos de fibrina em 46% dos pulmões estudados, o que estabelece o diagnóstico da coagulação intravascular disseminada e a ocorrência da síndrome de angústia respiratória na leptospirose.

  14. Vrapci na tlu

    Directory of Open Access Journals (Sweden)

    Ana Ille Horvat

    2017-12-01

    Full Text Available Princeze nikada ne umiru. Udaju se i žive sretno do kraja života. "Ideja će mi sinuti kad se najmanje budem nadala", kaže Alice, "uvijek je tako. Neću očajavati." Upravo sjedi na kauču držeći bilježnicu u rukama u koju je trenutak prije, velikim štampanim slovima na vrhu lista, upisala "ideje za Afonsov rođendan". Pažljivo je povukla pet strelica i svaku označila brojem. Poslije toga nije napisala više ništa. Ovo je već sedmi popis koji radi otkako je sjela. Pogleda uprta prema dnevnom boravku, oko kažiprsta lijeve ruke mota plamen jarkoplave kose, kao u lutke."Kako se to smišlja neka ideja", upita se šapatom koji je uvježbala još u mladosti, "kako?"

  15. Ergodicity of Random Walks on Random DFA

    OpenAIRE

    Balle, Borja

    2013-01-01

    Given a DFA we consider the random walk that starts at the initial state and at each time step moves to a new state by taking a random transition from the current state. This paper shows that for typical DFA this random walk induces an ergodic Markov chain. The notion of typical DFA is formalized by showing that ergodicity holds with high probability when a DFA is sampled uniformly at random from the set of all automata with a fixed number of states. We also show the same result applies to DF...

  16. Random Access for Machine-Type Communication based on Bloom Filtering

    DEFF Research Database (Denmark)

    Pratas, Nuno; Stefanovic, Cedomir; Madueño, Germán Corrales

    2016-01-01

    We present a random access method inspired on Bloom filters that is suited for Machine-Type Communications (MTC). Each accessing device sends a signature during the contention process. A signature is constructed using the Bloom filtering method and contains information on the device identity...... utilizes the system resources more efficiently and achieves similar or lower latency of connection establishment in case of synchronous arrivals, compared to the variant of the LTE-A access protocol that is optimized for MTC traffic. A dividend of the proposed method is that allows the base station (BS...

  17. Random fractional Fourier transform.

    Science.gov (United States)

    Liu, Zhengjun; Liu, Shutian

    2007-08-01

    We propose a novel random fractional Fourier transform by randomizing the transform kernel function of the conventional fractional Fourier transform. The random fractional Fourier transform inherits the excellent mathematical properties from the fractional Fourier transform and can be easily implemented in optics. As a primary application the random fractional Fourier transform can be directly used in optical image encryption and decryption. The double phase encoding image encryption schemes can thus be modeled with cascaded random fractional Fourier transformers.

  18. Rare kaon decays (NA48/2 and NA62)

    OpenAIRE

    Goudzovski, Evgueni

    2013-01-01

    The rare decay $K^\\pm\\to\\pi^\\pm\\gamma\\gamma$ has been recently measured from data samples collected by the NA48/2 and NA62 experiments at CERN. These measurements are presented, including model-independent spectrum measurements and fits to the Chiral Perturbation Theory description. The rare decay $K^\\pm\\to\\pi^\\pm\\gamma\\gamma$ has been recently measured from data samples collected by the NA48/2 and NA62 experiments at CERN. These measurements are presented, including model-independent spec...

  19. EXPERIMENTAL RESEARCHES OF ELECTRO-THERMAL RESISTIBILITY OF SEND-OFFS AND CABLES TO ACTION RATIONED ON THE INTERNATIONAL STANDARD OF IEC 62305-1-2010 OF APERIODIC IMPULSE OF CURRENT OF ARTIFICIAL LIGHTNING

    Directory of Open Access Journals (Sweden)

    M.I. Baranov

    2016-03-01

    Full Text Available Purpose. Experimental researches of electro-thermal resistibility of cable-explorer products, applied in the power electric circuits of objects of electric-power industry, to action on its copper and aluminum parts bearings a current rationed on the International Standard of IEC 62305-1-2010 aperiodic impulse 10/350 μs of current of artificial lightning. Methodology. Electrophysics bases of technique of high tensions and high pulsed currents (HPC, and also scientific and technical bases of planning of devices of high-voltage impulsive technique and measuring HPC in them. Results. Experimental a way the quantitative levels of maximal values maximum of possible and critical closenesses of aperiodic impulse 10/350 μs of current of artificial lightning with rationed on the international standard of IEC 62305-1-2010 peak-temporal parameters and admittances on them in copper (aluminum parts bearings a current of send-offs and cables with a polyethylene (PET and polyvinylchloride (PVCH isolation. Originality. First in world practice on the unique powerful high-voltage generator of HPC of artificial lightning experimental researches of resistibility to lightning of pre-production models of send-offs (cables are conducted with copper (aluminum tendons, PET and PVCH by an isolation, in-use in power electric circuits of electric-power industry objects. Practical value. The use in practice of protecting from lightning of the got results will allow substantially to promote functional and fire-prevention safety of engineering communications of objects of industrial electroenergy in the conditions of action on them of short shots of linear lightning.

  20. Synchronizing microelectrode and electronic goniometer data using a pseudo-random binary signal.

    Science.gov (United States)

    Moore, Tyler Robert; Jacobs, Rennie Underwood; Yang, Alexander Cheung; Richter, Erich Oscar

    2013-04-01

    Intra-operative investigation of the subthalamic nucleus (STN) requires concurrent measurement of microelectrode voltage, electrode depth and joint movement during deep brain stimulation (DBS) surgery. Commercial solutions to this problem exist but are more expensive. Multiple instruments from different manufacturers can collect the same data, but data from incompatible instruments are collected on disparate clocks, precluding quantitative analysis. A pseudo-random binary signal recorded simultaneously by each set of instruments allows for chronological reconciliation. A custom program collects microelectrode data while simultaneously sending a pseudo-random binary signal to instruments measuring joint movement. The record of this signal is later used to express microelectrode voltage and joint position in a single chronological frame of reference. ClockSynch was used in 15 DBS procedures. After each surgery, records of microelectrode and joint movement were successfully chronologically reconciled. In conclusion, a pseudo-random binary signal integrates disparate systems of instrumentation at a significantly decreased cost.

  1. Robotic vision system for random bin picking with dual-arm robots

    Directory of Open Access Journals (Sweden)

    Kang Sangseung

    2016-01-01

    Full Text Available Random bin picking is one of the most challenging industrial robotics applications available. It constitutes a complicated interaction between the vision system, robot, and control system. For a packaging operation requiring a pick-and-place task, the robot system utilized should be able to perform certain functions for recognizing the applicable target object from randomized objects in a bin. In this paper, we introduce a robotic vision system for bin picking using industrial dual-arm robots. The proposed system recognizes the best object from randomized target candidates based on stereo vision, and estimates the position and orientation of the object. It then sends the result to the robot control system. The system was developed for use in the packaging process of cell phone accessories using dual-arm robots.

  2. Random walks in a random environment

    Indian Academy of Sciences (India)

    Home; Journals; Proceedings – Mathematical Sciences; Volume 114; Issue 4. Random Walks in a Random Environment. S R S Varadhan. Invited Articles Volume 114 Issue ... Author Affiliations. S R S Varadhan1. Department of Mathematics, Courant Institute of Mathematical Sciences, New York University, NY 10012, USA ...

  3. Random walks on random Koch curves

    Energy Technology Data Exchange (ETDEWEB)

    Seeger, S; Hoffmann, K H [Institut fuer Physik, Technische Universitaet, D-09107 Chemnitz (Germany); Essex, C [Department of Applied Mathematics, University of Western Ontario, London, ON N6A 5B7 (Canada)

    2009-06-05

    Diffusion processes in porous materials are often modeled as random walks on fractals. In order to capture the randomness of the materials random fractals are employed, which no longer show the deterministic self-similarity of regular fractals. Finding a continuum differential equation describing the diffusion on such fractals has been a long-standing goal, and we address the question of whether the concepts developed for regular fractals are still applicable. We use the random Koch curve as a convenient example as it provides certain technical advantages by its separation of time and space features. While some of the concepts developed for regular fractals can be used unaltered, others have to be modified. Based on the concept of fibers, we introduce ensemble-averaged density functions which produce a differentiable estimate of probability explicitly and compare it to random walk data.

  4. NA48 prototype calorimeter

    CERN Multimedia

    1990-01-01

    This is a calorimeter, a detector which measures the energy of particles. When in use, it is filled with liquid krypton at -152°C. Electrons and photons passing through interact with the krypton, creating a shower of charged particles which are collected on the copper ribbons. The ribbons are aligned to an accuracy of a tenth of a millimetre. The folding at each end allows them to be kept absolutely flat. Each shower of particles also creates a signal in scintillating material embedded in the support disks. These flashes of light are transmitted to electronics by the optical fibres along the side of the detector. They give the time at which the interaction occurred. The photo shows the calorimeter at NA48, a CERN experiment which is trying to understand the lack of anti-matter in the Universe today.

  5. O real na psicose

    Directory of Open Access Journals (Sweden)

    Maurício Castejón Herrmann

    2004-06-01

    Full Text Available Este artigo discute a noção de real na psicose, a partir das formulações de Lacan sobre o tema, presentes no Seminário 3 - As Psicoses, no Seminário 20 - Mais, Ainda e no texto Televisão. Considerando-se que a concepção de real tem uma indicação clínica, a hipótese que se formula é a de que a noção de real trabalhada no Seminário 20, Mais, Ainda representa uma continuidade da concepção de real desenvolvida no Seminário 3, As Psicoses

  6. Na Cauda do Cometa

    Science.gov (United States)

    Voelzke, M. R.

    2009-01-01

    Quando viam um cometa, os antigos gregos imaginavam uma estrela com uma vasta cabeleira. Não à toa, a palavra deriva do termo koma, que significa cabelo. Constituídos por fragmentos de gelo e gases, os cometas possuem um núcleo sólido, que pode ter vários quilômetros de diâmetro, e uma cauda que sempre aponta na direção contrária ao Sol, devido aos ventos solares. Graças à aparência de pontos luminosos em movimento (ao contrário de outros astros, que parecem estáticos), esses corpos celestes foram interpretados por diferentes povos com muito misticismo, inspirando mitos tanto de boas-novas como de maus presságios. Conheça algumas dessas histórias:

  7. Athéna

    OpenAIRE

    Camps, G.

    2013-01-01

    Dès l’époque archaïque le culte d’Athéna fut important à Cyrène au point qu’on a pu se demander si cette importance ne s’expliquait pas par l’existence d’une divinité libyque qui aurait été identifiée à la déesse guerrière et industrieuse. A l’appui de cette opinion, on peut retenir plusieurs données de qualités diverses. Il faut citer en premier lieu la déesse égypto-libyque Nît, très ancienne mais particulièrement adorée durant l’époque saïte, au moment où la Basse-Egypte est soumise à une ...

  8. Comprometimento pulmonar na leptospirose

    Directory of Open Access Journals (Sweden)

    Jorge Eduardo Manhães de Carvalho

    1992-03-01

    Full Text Available Em 23 pacientes com leptospirose apresentando comprometimento pulmonar, internados no Hospital Universitário Antônio Pedro da XJFF, Niterói, hemoptise e hemoptóicos foram observados em 21,7% e 30,4%, respectivajnente. Gasometria arterial revelou hipoxemia e hipocapnia na maioria dos casos. Radiografia de tórax em 15 pacientes mostrou comprometimento alveolar em 60%, comprometimento intersticial-reticular em 6%, padrão misto (alveolar e intersticial em20%e ausência de alterações radiológicas em 14%. A necrópsiade 13 pacientes mostrou edema, congestão e hemorragia nos pulmões em 100% dos casos. A hemorragia foi focal em 46% e difusa em 54% dos casos. Houve formação de membrana hialina em 30% e trombos de fibrina em 46% dos pulmões estudados, o que estabelece o diagnóstico da coagulação intravascular disseminada e a ocorrência da síndrome de angústia respiratória na leptospirose.Tostudy thepulmonary complications in leptospirosis case records of 23 such patients admitted at the Hospital Universitário Antônio Pedro, Universidade Federal Fluminense, Niterói, Brasil, were reviewed. Hemoptysis were seen in 21.7% and sputal blood in 30.4% of patients. Arterial gasometry detected hypoxemia and hypocapnia in most cases. Thoracic radiology showed an alveolar pattern in 60% of the patients, alveolo-interstitial in 20%, interstitial in 6%, and in 14% the lungs were considered to be normal Necropsy of 13 cases showed edema, congestion and hemorrhage in the lungs in all cases. Hyaline membrane was found in 30% and fibrin thrombi in 46% of these cases, resulting in a diagnosis of adult respiratory distress syndrome and acute disseminated intravascular coagulation (consumption coagulopathy in leptospirosis.

  9. A ENGENHARIA NA ESCOLA

    Directory of Open Access Journals (Sweden)

    Valéria Pelizzer Casara

    2015-04-01

    Full Text Available Este projeto teve por objetivo principal mostrar às jovens do ensino médio, como as áreas de exatas e de engenharia podem estar inseridas em situações rotineiras por elas vivenciadas e incentivá-las para ingressarem nessas áreas. O projeto foi executado na escola de ensino Médio Nelson Horostecki na cidade de Chapecó, Santa Catarina. Mostrou-se de forma simples que as áreas de exatas e de engenharia têm aplicações práticas nas nossas vidas. No desenvolvimento do projeto, realizaram-se oficinas na escola cujo tema principal abordado foi o processo de fabricação do chocolate, visto que o mesmo é um produto muito apreciado pelas adolescentes. Dentro dessa temática, foram trabalhadas as questões que envolvem conhecimentos das áreas de exatas e de engenharia, mais especificamente a Engenharia Ambiental. O projeto auxiliou na formação cidadã e também na escolha profissional das meninas. Muitas das alunas participantes nunca haviam tido contato direto com alunos graduandos de cursos na área das exatas. Mais ainda, este projeto oportunizou a aproximação da universidade com a comunidade externa. Palavras-chave: Extensão Universitária, Ciências Exatas e Engenharia, Chocolate, Oficinas.   Engineering in the school Abstract: The main objective of this project was to show high school female students how the exact sciences and engineering can be included in their routine situations encouraging them to entering in these areas. The project was carried out at the Nelson Horostecki High School in Chapecó, Santa Catarina State, Brazil. It was showed in a simple manner how exact sciences and engineering have practical applications in our lives. Workshops were conducted in the school during the execution of the project in which the main subject was the chocolate manufacturing process, since chocolate is a product greatly appreciated by the young female people. Within this matter, the activities were performed using the knowledge of

  10. Kaon experiments at CERN: NA48 and NA62

    CERN Document Server

    INSPIRE-00293758

    2012-01-01

    Searches for violation of lepton flavour universality and lepton number conservation in kaon decays by the NA62 and NA48/2 experiments at CERN, status and future plans of the CERN kaon programme are presented. A precision measurement of the helicity-suppressed ratio $R_K$ of the $K^\\pm\\to e^\\pm\

  11. Microstructure Analyses of NA-Nanodiamond Particles

    Science.gov (United States)

    2016-08-01

    approximately 5 to 6 nm in diameter, similar to those obtained by distilled water purification . The energy dispersive analyzer from these perfectly well... searching existing data sources, gathering and maintaining the data needed, and completing and reviewing the collection of information. Send comments...NOTES 14. ABSTRACT The purification process of detonation diamond nanoparticles was perfectly accomplished using nitric acid at high

  12. Romanskoe vlijanie na staroserbskij sintaksis

    Directory of Open Access Journals (Sweden)

    Pavlović Slobodan

    2010-01-01

    Full Text Available V nastojaščej rabote rassmatrivajutsja kontekstual'nye aspekty vlijanija romanskogo substrata i adstrata na staroserbskij sintaksis. Na sintaksis staroserbskogo razgovornogo jazyka mogli vlijat' vlašskie, dalmatinskie i ital'janskie dialekty. Na sintaksis staroserbskoj pis'mennosti (krome serbsko-slavjanskogo jazyka i romanskogo substrata okazali vlijanie latinskij i ital'janskij jazyki, poskol'ku na territorii rasprostranenija serbskogo jazyka peresekalis' dve velikie kul'tury: Pax Slavia Orthodoxa i Pax Romana Catholica. Sintaksičeskoe vlijanie latinskogo i ital'janskogo jazykov na staro-serbskuju pis'mennost' osuščestvljalos' prežde vsego čerez zapadnye obrazcy delovoj perepiski. [Projekat Ministarstva nauke Republike Srbije: Istorija srpskog jezika

  13. Valores na escola

    Directory of Open Access Journals (Sweden)

    Menin Maria Suzana De Stefano

    2002-01-01

    Full Text Available Neste texto pretende-se discorrer sobre valores morais na escola e suas implicações para a formação de professores. Para tanto discutir-se-á, em primeiro lugar, e brevemente, o que são valores morais, ou éticos, e como a escola pode situar-se em relação a eles. Em seguida, serão relatadas algumas observações a respeito de valores de professores e práticas daí decorrentes. São comentados resultados de pesquisa que ilustram a transmissão de valores de forma doutrinal e a educação moral e cívica tal como realizada na ditadura militar, e, por outro lado, a posição relativista e/ou de laissez-faire que certas escolas podem adotar, metodologicamente, sobre a educação em valores. Finalmente, defender-se-á a idéia de que é necessária uma discussão sobre valores pelos diversos membros da escola e uma opção por uma metodologia para ensiná-los, seja os professores, em sua formação inicial e continuada, seja os alunos. A teoria de desenvolvimento moral de Jean Piaget será apresentada como uma referência possível para a educação em valores. Exemplos de situações escolares de conflito de valores entre direção, pais e alunos são discutidas para ilustrar como uma escola pode adotar um procedimento democrático de educação em valores, que se apresenta como um terceiro caminho possível de educação moral nas escolas, além das posições doutrinárias ou relativistas.

  14. Efeito de um programa de resistência muscular na capacidade funcional e na força muscular dos extensores do joelho em idosas pré-frágeis da comunidade: ensaio clínico aleatorizado do tipo crossover Impact of resistance exercise program on functional capacity and muscular strength of knee extensor in pre-frail community-dwelling older women: a randomized crossover trial

    Directory of Open Access Journals (Sweden)

    Lygia P. Lustosa

    2011-08-01

    Full Text Available CONTEXTUALIZAÇÃO: Na síndrome de fragilidade em idosos, há diminuição das reservas de energia e resistência aos estressores, com aumento da vulnerabilidade. OBJETIVO: Verificar o efeito do treinamento de força muscular com carga na capacidade funcional e força muscular dos extensores do joelho e sua associação, após treinamento, em idosas pré-frágeis da comunidade. MÉTODOS:Participaram 32 idosas, pré-frágeis, da comunidade. Excluíram-se aquelas com Miniexame do Estado Mental (MEEM incompatível; cirurgias ortopédicas dos membros inferiores; fraturas; doenças neurológicas; doenças inflamatórias agudas; neoplasias; atividade física regular; uso de medicamento com ação no sistema imunológico e sem marcha independente. Avaliou-se a capacidade funcional (Timed Up and Go - TUG e velocidade de marcha - TC10 e a força muscular dos extensores do joelho (Byodex System 3 Pro® nas velocidades angulares de 60 e 180(0/s. Para o fortalecimento muscular, utilizou-se carga de 75% de resistência máxima (1RM, durante dez semanas, três vezes/semana. A análise estatística foi feita pela ANOVA e Spearman (α=5%. RESULTADOS: Após o treinamento, houve melhora estatística do trabalho normalizado em 180(0/s (F=12,71, p=0,02, na potência, em 180(0/s (F=15,40, p=0,02 e na capacidade funcional (TUG, F=9,54, p=0,01; TC10, F=3,80, p=0,01. Houve boa correlação negativa significativa do TUG com as medidas de trabalho normalizado em 60 e 180(0/s (r=-0,65, p=0,01; r=-0,72, p=0,01. CONCLUSÃO: O treinamento produziu melhora da potência muscular e capacidade funcional. A melhora da potência associou-se à melhora funcional, importante variável para a qualidade de vida de idosas pré-frágeis. Artigo registrado no ISRCT register sob o número ISRCTN62824599.BACKGROUND: Frailty syndrome in elderly people is characterized by a reduction of energy reserves and also by a decreased of resistance to stressors, resulting in an increase of

  15. Random matrices, random processes and integrable systems

    CERN Document Server

    2011-01-01

    This book explores the remarkable connections between two domains that, a priori, seem unrelated: Random matrices (together with associated random processes) and integrable systems. The relations between random matrix models and the theory of classical integrable systems have long been studied. These appear mainly in the deformation theory, when parameters characterizing the measures or the domain of localization of the eigenvalues are varied. The resulting differential equations determining the partition function and correlation functions are, remarkably, of the same type as certain equations appearing in the theory of integrable systems. They may be analyzed effectively through methods based upon the Riemann-Hilbert problem of analytic function theory and by related approaches to the study of nonlinear asymptotics in the large N limit. Associated with studies of matrix models are certain stochastic processes, the "Dyson processes", and their continuum diffusion limits, which govern the spectrum in random ma...

  16. Send mixed signals : earn more, work less

    DEFF Research Database (Denmark)

    Miltersen, Peter Bro; Sheffet, Or

    2012-01-01

    Emek et al presented a model of probabilistic single-item second price auctions where an auctioneer who is informed about the type of an item for sale, broadcasts a signal about this type to uninformed bidders. They proved that finding the optimal (for the purpose of generating revenue) pure sign...

  17. Send hele det "fejlslagne" Skat i udlicitering

    DEFF Research Database (Denmark)

    Andersen, Kim Normann

    2017-01-01

    En pendant til udbetaling Danmark er løsningen på Skats problemer med at få pengene indbetalt. ... Det vil løsne de snævre bånd som de offentlige myndigheder har, når de skal købe digitale løsninger. De private kan vælge bedst og billigst med langt kortere tidshorisont og uden at gamble med...

  18. The curriculum vitae sending the right message.

    Science.gov (United States)

    Shellenbarger, Teresa; Chunta, Kristy S

    2007-01-01

    When reviewing curriculum vitae (CV), it becomes clear that some CV information provides a better reflection of work completed than others do. The authors provide a description of common CV errors, propose strategies to avoid such problems, and suggest methods for developing an accurate and clear CV that highlights accomplishments and clearly represents the work. Tips for updating CV and suggestions for electronic formats are also provided.

  19. Sending a message to the other side

    Science.gov (United States)

    2017-05-01

    A range of mechanisms have evolved for communicating information across cell membranes, but designing synthetic analogues is far from trivial. A collection of articles in this issue discuss different methods of passing chemical information across lipid bilayers using artificial systems.

  20. CERN’s surveyors send sparks flying

    CERN Multimedia

    Anaïs Schaeffer

    2013-01-01

    A few weeks ago, we published an article on the three-dimensional laser scanner technique used at CERN to produce 3D images of the LHC tunnels and experiments (see the article here). Photogrammetry is another technique in the CERN surveyors’ arsenal.   The ATLAS wheel during a photogrammetry measurement campaign. The white spots (see red arrows) dotted across the wheel are the retro-reflective "dot" targets. Used in a number of fields including topography, architecture, geology and archaeology, photogrammetry is a stereoscopy technique whereby 2D images taken from different angles can be used to reconstruct a 3D image of an object. Surveyors at CERN have been using this technique for over 15 years as a way of gaining precise information on the shape, size, deformation and position of the LHC detectors and their composite elements. The photogrammetry used at CERN is relatively “light” in terms of the equipment required, w...

  1. DIE PERSOON VAN VREDE IN DIE SENDING

    African Journals Online (AJOL)

    6. KOMMUNIKASIE VAN DIE EVANGELIE EN. SENTRALE FIGURE IN DIE GEMEENSKAP. Die kommunikasie van die evangelie in gemeenskappe word dikwels bevorder of bemoeilik deur die persoon van die sendeling en die persone tot wie hy/sy hom rig. Dit is inderdaad so dat mense 'n belangrike rol kan speel in die ...

  2. Sending Public School Students to Private Schools.

    Science.gov (United States)

    Fox, Jonathan

    1999-01-01

    Public schools often contract with private schools to meet the needs of special-education students. When disagreement exists about placement, parents can forego the Individuals with Disabilities Education Act (IDEA) placement process in exchange for private education which is only partially subsidized by the government. Vouchers would provide…

  3. Torchwood sends inspection team to CERN

    CERN Multimedia

    Sherriff, Lucy

    2007-01-01

    "Torchwood's Captain Jack has been sighted at CERN's Large Hadron Collider. Does this mean that when it is switched on it is likely to open a rift under Cardiff from whence all manner of spooky things shall spring?" (1/2 page)

  4. Die Gereformeerde ekumeniese sinode en sending 1984

    Directory of Open Access Journals (Sweden)

    H. G. van der Westhuizen

    1985-01-01

    Full Text Available The Reformed Ecumenical Synod and Mission 1984 The Afrikaner nation in South Africa is a minority in its own country. The normal strive to become and stay sovereign is blamed in the face of the world as building concentration camps! That is a lie. And if the world is not prepared to accept it as a lie we are sure that in this sense God will be on the side of the powerless. The Nederduitsch Hervormde Kerk already accommodates specific points of mission strategy as stated at the Chicago Conference. Especially the aim of independent indigenous national churches, founded on sound Biblical theology, is held in high esteem.

  5. Sending Quantum Information with Gaussian States

    Science.gov (United States)

    Holevo, Alexander S.

    Quantum information characteristics, such as quantum mutual information, loss, noise and coherent information are explicitly calculated for Bosonic attenuation/amplification channel with input Gaussian state. The coherent information is shown to be negative for the values of the attenuation coefficient k < 1sqrt 2.

  6. Sending Quantum Information with Gaussian States

    OpenAIRE

    Holevo, Alexander S.

    1998-01-01

    Quantum information characteristics, such as quantum mutual information, loss, noise and coherent information are explicitly calculated for Bosonic attenuation/amplification channel with input Gaussian state. The coherent information is shown to be negative for the values of the attenuation coefficient $k

  7. Brian Honyouti: Send in the Clowns

    Science.gov (United States)

    Pearlstone, Zena

    2012-01-01

    Hopi Brian Honyouti's "clown" sculptures stem from his personal and political views and comment on commercialism, big business, greed, over indulgence, and irresponsible and sexual behavior. This essay explores the meaning of these carvings to Honyouti, to Hopiit, and to the buying public, as well as their relationship to "tithu," the carved…

  8. O SUBLIME NA MODERNIDADE

    Directory of Open Access Journals (Sweden)

    Martha de Almeida

    2009-03-01

    Full Text Available A obra Uma investigação filosófica sobre a origem de nossas idéias do sublime e dobelo, do sensualista inglês Edmund Burke (1757, data as origens do sublime na Modernidade. Nosublime ocorre é um prazer ligado à dor, um "horror delicioso" que sentimos quando acreditamosque estamos em perigo sem que isso esteja ocorrendo realmente. Em O mundo como Vontade erepresentação Schopenhauer assume as influências que sofreu de Kant no que diz respeito à suainterpretação sobre o belo e o sublime, porém difere dele quanto à natureza dessa impressão. ParaSchopenhauer a experiência estética pressupõe a dissolução da subjetividade num movimento decontemplação das idéias livre do querer imposto pela vontade individual. As idéias deSchopenhauer influenciaram a estética do Nietzsche de O nascimento da tragédia.

  9. A aposta na filosofia

    Directory of Open Access Journals (Sweden)

    Márcio Suzuki

    2011-12-01

    Full Text Available Para Hume, filosofar é uma atividade semelhante às demais ocupações humanas. A decisão que leva à atividade filosófica é menos resultado de uma argumentação teórica do que fruto de um cálculo prático, que é entendido como uma caça ou um jogo. O objetivo deste trabalho será o de mostrar que no jogo filosófico perde quem joga sério demais. A aposta na filosofia tem que passar pelo bom humor e pela diversão: uma resposta a Pascal?For Hume, philosophy is in itself neither more nor less important than other human activities. On the contrary, it can be explained from its resemblance with game and hunting. If one chooses to dedicate himself to philosophy, his decision is not the consequence of logical reasoning, but depends on practical evaluation, which has something to do with gambling. The following text tries to show that in philosophy, like in other games, the loser will be the one who plays too earnestly. The philosophical game requires good humour and some relaxation: Is this a good answer to Pascal's pari?

  10. Misuse of randomization

    DEFF Research Database (Denmark)

    Liu, Jianping; Kjaergard, Lise Lotte; Gluud, Christian

    2002-01-01

    The quality of randomization of Chinese randomized trials on herbal medicines for hepatitis B was assessed. Search strategy and inclusion criteria were based on the published protocol. One hundred and seventy-six randomized clinical trials (RCTs) involving 20,452 patients with chronic hepatitis B....../150) of the studies were imbalanced at the 0.05 level of probability for the two treatments and 13.3% (20/150) imbalanced at the 0.01 level in the randomization. It is suggested that there may exist misunderstanding of the concept and the misuse of randomization based on the review....

  11. Exercício físico como tratamento na osteoartrite de quadril: uma revisão de ensaios clínicos aleatórios controlados Exercise therapy as a treatment in osteoarthritis of the hip: a review of randomized clinical trials

    Directory of Open Access Journals (Sweden)

    Natália Aquaroni Ricci

    2006-08-01

    Full Text Available As funções do quadril são cruciais para a independência funcional de um indivíduo, motivo da grande repercussão da osteoartrite (OA sobre as alterações nessa articulação. A OA de quadril é uma doença crônico-degenerativa e o tratamento atual detém-se em combater sua sintomatologia. Dentre os possíveis tratamentos conservadores, os exercícios têm sido indicados para a redução da dor e melhora funcional. O objetivo desta revisão sistemática é elucidar a função e efetividade dos exercícios físicos no tratamento conservador da OA de quadril. Para a realização do levantamento bibliográfico foram consultadas as bases de dados PUBMED, LILACS e MEDLINE referentes às publicações de artigos de ensaio clínico aleatório controlado dos últimos dez anos (julho/2005 - julho/1995, utilizando-se a relação entre as palavras-chave osteoarthritis, hip, exercise. Resultaram da busca, 18 artigos. Desses, dez continham os critérios para revisão na íntegra. Após análise do conteúdo dos dez estudos, foram identificadas três categorias: a exercícios específicos para OA de quadril (n=3; b exercícios para OA de quadril e joelho (n=4 e c exercícios para pré e pós-cirurgia de artroplastia decorrente de OA (n=3. Dos dez estudos analisados, três revelaram limitações dos benefícios dos exercícios nas amostras. Embora, a maioria dos estudos tenha demonstrado bons resultados com a prática de exercícios no tratamento da OA de quadril, ainda não é possível determinar o alcance deste tipo de terapêutica no quadro geral da doença e para sua progressão, tendo em vista a escassez de estudos e falta de especificidade das intervenções propostas.Functions of the hip are crucial for the functional independence of an individual, being the reason of great repercussion of Osteoarthritis (OA on the alterations in this joint. Hip OA is a chronic degenerative disease and the available treatment aims to alleviate its symptoms

  12. Efeito da rotação da cabeça na pressão intraocular em decúbito ventral: estudo randomizado Efecto de la rotación de la cabeza en la presión intraocular en decúbito ventral: estudio aleatorio The effect of head Rotation on intraocular pressure in prone position: a randomized trial

    Directory of Open Access Journals (Sweden)

    M. Nuri Deniz

    2013-04-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A elevação da pressão intraocular (PIO, que diminui a pressão de perfusão do nervo óptico, é aumentada pelo posicionamento em decúbito ventral. O objetivo de nosso estudo foi comparar o efeito da rotação lateral da cabeça a 45º em decúbito ventral no aumento da PIO de olhos posicionados para cima e olhos posicionados para baixo em pacientes submetidos à nefrolitotomia percutânea (NLPC. MÉTODOS: Quarenta e cinco pacientes foram randomicamente alocados em dois grupos. A PIO dos pacientes foi registrada bilateralmente em posição supina antes do início da operação. Os pacientes foram posicionados em decúbito ventral. A cabeça foi posicionada sobre um apoio sem compressão externa direta em ambos os olhos. Os pacientes do Grupo I foram estritamente mantidos em pronação neutra, enquanto os pacientes do Grupo II foram posicionados em pronação com rotação da cabeça a 45º para o lado direito. No fim da operação, os pacientes foram reposicionados em decúbito dorsal e a PIO foi imediatamente medida. RESULTADOS: Não houve diferença entre os dados demográficos, na duração da cirurgia, perda de sangue e reposição de líquido dos pacientes. Os valores pós-cirúrgicos da PIO em decúbito ventral aumentaram significativamente em comparação com os valores pré-operatórios em ambos os grupos (p JUSTIFICATIVA Y OBJETIVOS: La elevación de la presión intraocular (PIO, que disminuye la presión de perfusión del nervio óptico, es aumentada por el posicionamiento en decúbito ventral. El objetivo de nuestro estudio, fue comparar el efecto de la rotación lateral de la cabeza a 45o en decúbito ventral en el aumento de la PIO de ojos posicionados hacia arriba y ojos posicionados hacia abajo en pacientes sometidos a la nefrolitotomia percutánea (NLPC. MÉTODOS: Cuarenta y cinco pacientes fueron aleatoriamente divididos en dos grupos. La PIO de los pacientes fue registrada bilateralmente en posici

  13. Relationship between intracellular Na+ concentration and reduced Na+ affinity in Na+,K+-ATPase mutants causing neurological disease

    DEFF Research Database (Denmark)

    Toustrup-Jensen, Mads Schak; Einholm, Anja P.; Schack, Vivien

    2014-01-01

    The neurological disorders familial hemiplegic migraine type 2 (FHM2), alternating hemiplegia of childhood (AHC), and rapid-onset dystonia parkinsonism (RDP) are caused by mutations of Na+,K+-ATPase α2- and α3-isoforms, expressed in glial and neuronal cells, respectively. Although these disorders...... mutations that increase Na+ affinity were found to reduce [Na+]i. It is concluded that the Na+ affinity of the Na+,K+-ATPase is an important determinant of [Na+]i....

  14. Hemisferectomia na hemiplegia infantil

    Directory of Open Access Journals (Sweden)

    Rolando A. Tenuto

    1956-03-01

    Full Text Available Os autores relatam o caso de um paciente com 18 anos de idade, portador de paralisia cerebral instalada aos 4 anos de idade após moléstia febril prolongada (hemiplegia esquerda, crises convulsivas generalizadas, freqüentes e rebeldes à medicação, deficiência mental e alterações de conduta. O eletrencefalograma e o pneumencefalograma revelaram alterações graves do hemisfério direito; tendo o primeiro destes exames demonstrado a existência de perturbações propagadas ao outro hemisfério. Foi praticada a hemisferectomia direita. Durante o ato cirúrgico, por exigência técnica foram extirpados, além do hemisfério cerebral, os dois terços rostrais do núcleo caudado e o núcleo amigdalóide. No pós-operatório foi intercorrência de osteomielite e meningite, medicadas com antibióticos e seqüestrectomia. Apesar da complicação pós-operatória, instalou-se progressiva melhora em relação à conduta social; diminuiu também a espasticidade no membro inferior esquerdo e não mais se repetiram as crises convulsivas. Não foram observadas modificações quanto ao rendimento intelectual e quanto aos distúrbios sensitivos que existiam antes da intervenção cirúrgica. O exame neurocular mostrou hemianopsia homônima esquerda. Êstes resultados são concordantes com os assinalados na literatura sobre o assunto.

  15. TRGOVANJE NA IZBRANEM TRGU - FOREX

    OpenAIRE

    Ambrož, Sabina

    2012-01-01

    V delu diplomskega seminarja je obravnavana tematika trgovanja na valutnem trgu. Trgovanje z valutami je v zadnjem desetletju doseglo velik razvoj, močno pa je narasla tudi priljubljenost valutnega trga Forex, saj se zaradi enostavnega pristopa in možnosti velikih zaslužkov zanj odloča vse več posameznikov. V teoretičnem delu povzamemo ključne elemente, ki jih mora poznati začetnik na tem trgu. V empiričnem delu pa poskušamo na praktičnem primeru pokazati primer trgovanja s trendom in vstopom...

  16. Blocked Randomization with Randomly Selected Block Sizes

    Directory of Open Access Journals (Sweden)

    Jimmy Efird

    2010-12-01

    Full Text Available When planning a randomized clinical trial, careful consideration must be given to how participants are selected for various arms of a study. Selection and accidental bias may occur when participants are not assigned to study groups with equal probability. A simple random allocation scheme is a process by which each participant has equal likelihood of being assigned to treatment versus referent groups. However, by chance an unequal number of individuals may be assigned to each arm of the study and thus decrease the power to detect statistically significant differences between groups. Block randomization is a commonly used technique in clinical trial design to reduce bias and achieve balance in the allocation of participants to treatment arms, especially when the sample size is small. This method increases the probability that each arm will contain an equal number of individuals by sequencing participant assignments by block. Yet still, the allocation process may be predictable, for example, when the investigator is not blind and the block size is fixed. This paper provides an overview of blocked randomization and illustrates how to avoid selection bias by using random block sizes.

  17. Blocked randomization with randomly selected block sizes.

    Science.gov (United States)

    Efird, Jimmy

    2011-01-01

    When planning a randomized clinical trial, careful consideration must be given to how participants are selected for various arms of a study. Selection and accidental bias may occur when participants are not assigned to study groups with equal probability. A simple random allocation scheme is a process by which each participant has equal likelihood of being assigned to treatment versus referent groups. However, by chance an unequal number of individuals may be assigned to each arm of the study and thus decrease the power to detect statistically significant differences between groups. Block randomization is a commonly used technique in clinical trial design to reduce bias and achieve balance in the allocation of participants to treatment arms, especially when the sample size is small. This method increases the probability that each arm will contain an equal number of individuals by sequencing participant assignments by block. Yet still, the allocation process may be predictable, for example, when the investigator is not blind and the block size is fixed. This paper provides an overview of blocked randomization and illustrates how to avoid selection bias by using random block sizes.

  18. Results from NA61/SHINE

    Directory of Open Access Journals (Sweden)

    Unger M.

    2013-06-01

    Full Text Available In this paper we summarize recent results from NA61/SHINE relevant for heavy ion physics, neutrino oscillations and the interpretation of air showers induced by ultra-high energy cosmic rays.

  19. ŠOLANJE NA DOMU

    OpenAIRE

    Horvat, Anja

    2016-01-01

    Pravica do izobraževanja in pridobivanja (ne)formalnih veščin in spretnosti je temeljna človekova pravica in svoboščina. Dobra izobrazba človeka duhovno bogati, plemeniti in širi njegova obzorja. Šolanje oz. izobraževanje na domu je ena od možnosti za izvajanje izobraževanja na osnovnošolski ravni, ki ga v Republiki Sloveniji ureja Zakon o osnovni šoli (1996, 5. in 88. člen). Ta predpisuje obvezne učne vsebine in načine preverjanja znanja, od izvajalcev poučevanja na domu pa ne zahteva do...

  20. Beam monitoring at NA2

    CERN Multimedia

    1978-01-01

    Claus Goessling working on the beam Cerenkov counter of NA2. The muon beam enters from left the hall EHN2 and the last element of the beam transport. On background is the access door on the Jura side.

  1. Random walks, random fields, and disordered systems

    CERN Document Server

    Černý, Jiří; Kotecký, Roman

    2015-01-01

    Focusing on the mathematics that lies at the intersection of probability theory, statistical physics, combinatorics and computer science, this volume collects together lecture notes on recent developments in the area. The common ground of these subjects is perhaps best described by the three terms in the title: Random Walks, Random Fields and Disordered Systems. The specific topics covered include a study of Branching Brownian Motion from the perspective of disordered (spin-glass) systems, a detailed analysis of weakly self-avoiding random walks in four spatial dimensions via methods of field theory and the renormalization group, a study of phase transitions in disordered discrete structures using a rigorous version of the cavity method, a survey of recent work on interacting polymers in the ballisticity regime and, finally, a treatise on two-dimensional loop-soup models and their connection to conformally invariant systems and the Gaussian Free Field. The notes are aimed at early graduate students with a mod...

  2. Na via do Behemoth

    Directory of Open Access Journals (Sweden)

    Gérard Rabinovitch

    2008-06-01

    Full Text Available O momento nazista permanece um enigma impensado de que a cultura contemporânea continua cativa. O autor levanta a hipótese de que a persistência desse enigma e seus estragos duráveis se devem à insistência dos pensamentos político, sociológico e filosófico em construírem o nazismo à luz da metáfora hobbesiana do Leviatã. Propõe retomar a questão do nazismo sob a perspectiva do Behemoth, antônimo do Leviatã. Para tanto, sugere a necessidade de retornar a Freud e à psicanálise, balizas de um possível novo pensamento do político que escrutine a destrutividade nazista. Propõe ainda sondar as homologias entre nazismo, corjas e máfias, com base na figura da " heroicização da violência" que lhes seria comum. E avança um modelo " econômico" : a quimera, suscetível de capturar o caráter heterotópico e heterocrônico de sua construção criminosa.The paths of Behemoth. The Nazi moment remains as the thoughtless enigma of which contemporary culture is still captive. The author raises the hypothesis where the persistency of this enigma and its durable damages are due to the insistence of the political, social and philosophical thoughts in building the Nazism at the view of the Hobbesian metaphor of Leviathan. It is here proposed to resume the Nazism matter under Behemoth's perspective, antonym to Leviathan. For such, it is suggested a necessity to look back at Freud and the psychoanalysis, structured by a possible new political thought which scrutinizes the destructivity of the Nazism. It is also here proposed to gaze at the homologies between Nazism, mafias and gangs, with a base in the figure of " violence as a heroically act" that are their common ground. The author also advances an economical model: the chimera susceptible to capture the heterotopic and heterochronic character of its criminal construction.

  3. Random Access Performance of Distributed Sensors Attacked by Unknown Jammers.

    Science.gov (United States)

    Jeong, Dae-Kyo; Wui, Jung-Hwa; Kim, Dongwoo

    2017-11-18

    In this paper, we model and investigate the random access (RA) performance of sensor nodes (SN) in a wireless sensor network (WSN). In the WSN, a central head sensor (HS) collects the information from distributed SNs, and jammers disturb the information transmission primarily by generating interference. In this paper, two jamming attacks are considered: power and code jamming. Power jammers (if they are friendly jammers) generate noises and, as a result, degrade the quality of the signal from SNs. Power jamming is equally harmful to all the SNs that are accessing HS and simply induces denial of service (DoS) without any need to hack HS or SNs. On the other hand, code jammers mimic legitimate SNs by sending fake signals and thus need to know certain system parameters that are used by the legitimate SNs. As a result of code jamming, HS falsely allocates radio resources to SNs. The code jamming hence increases the failure probability in sending the information messages, as well as misleads the usage of radio resources. In this paper, we present the probabilities of successful preamble transmission with power ramping according to the jammer types and provide the resulting throughput and delay of information transmission by SNs, respectively. The effect of two jamming attacks on the RA performances is compared with numerical investigation. The results show that, compared to RA without jammers, power and code jamming degrade the throughput by up to 30.3% and 40.5%, respectively, while the delay performance by up to 40.1% and 65.6%, respectively.

  4. Random Access Performance of Distributed Sensors Attacked by Unknown Jammers

    Directory of Open Access Journals (Sweden)

    Dae-Kyo Jeong

    2017-11-01

    Full Text Available In this paper, we model and investigate the random access (RA performance of sensor nodes (SN in a wireless sensor network (WSN. In the WSN, a central head sensor (HS collects the information from distributed SNs, and jammers disturb the information transmission primarily by generating interference. In this paper, two jamming attacks are considered: power and code jamming. Power jammers (if they are friendly jammers generate noises and, as a result, degrade the quality of the signal from SNs. Power jamming is equally harmful to all the SNs that are accessing HS and simply induces denial of service (DoS without any need to hack HS or SNs. On the other hand, code jammers mimic legitimate SNs by sending fake signals and thus need to know certain system parameters that are used by the legitimate SNs. As a result of code jamming, HS falsely allocates radio resources to SNs. The code jamming hence increases the failure probability in sending the information messages, as well as misleads the usage of radio resources. In this paper, we present the probabilities of successful preamble transmission with power ramping according to the jammer types and provide the resulting throughput and delay of information transmission by SNs, respectively. The effect of two jamming attacks on the RA performances is compared with numerical investigation. The results show that, compared to RA without jammers, power and code jamming degrade the throughput by up to 30.3% and 40.5%, respectively, while the delay performance by up to 40.1% and 65.6%, respectively.

  5. The effect of NaCl 0.9% and NaCl 0.45% on sodium, chloride, and acid-base balance in a PICU population.

    Science.gov (United States)

    Almeida, Helena Isabel; Mascarenhas, Maria Inês; Loureiro, Helena Cristina; Abadesso, Clara S; Nunes, Pedro S; Moniz, Marta S; Machado, Maria Céu

    2015-01-01

    To study the effect of two intravenous maintenance fluids on plasma sodium (Na), and acid-base balance in pediatric intensive care patients during the first 24h of hospitalization. A prospective randomized controlled study was performed, which allocated 233 patients to groups: (A) NaCl 0.9% or (B) NaCl 0.45%. Patients were aged 1 day to 18 years, had normal electrolyte concentrations, and suffered an acute insult (medical/surgical). change in plasma sodium. Parametric tests: t-tests, ANOVA, X(2) statistical significance level was set at α=0.05. Group A (n=130): serum Na increased by 2.91 (±3.9)mmol/L at 24h (p<0.01); 2% patients had Na higher than 150 mmol/L. Mean urinary Na: 106.6 (±56.8)mmol/L. No change in pH at 0 and 24h. Group B (n=103): serum Na did not display statistically significant changes. Fifteen percent of the patients had Na<135 mmol/L at 24h. The two fluids had different effects on respiratory and post-operative situations. The use of saline 0.9% was associated with a lower incidence of electrolyte disturbances. Copyright © 2015 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. All rights reserved.

  6. The effect of NaCl 0.9% and NaCl 0.45% on sodium, chloride, and acid-base balance in a PICU population

    Directory of Open Access Journals (Sweden)

    Helena Isabel Almeida

    2015-10-01

    Full Text Available ABSTRACT OBJECTIVES: To study the effect of two intravenous maintenance fluids on plasma sodium (Na, and acid-base balance in pediatric intensive care patients during the first 24 h of hospitalization. METHODS: A prospective randomized controlled study was performed, which allocated 233 patients to groups: (A NaCl 0.9% or (B NaCl 0.45%. Patients were aged 1 day to 18 years, had normal electrolyte concentrations, and suffered an acute insult (medical/surgical. Main outcome measured: change in plasma sodium. Parametric tests: t-tests, ANOVA, X 2 statistical significance level was set at a = 0.05. RESULTS: Group A (n = 130: serum Na increased by 2.91 (±3.9 mmol/L at 24 h (p < 0.01; 2% patients had Na higher than 150 mmol/L. Mean urinary Na: 106.6 (±56.8 mmol/L. No change in pH at 0 and 24 h. Group B (n = 103: serum Na did not display statistically significant changes. Fifteen percent of the patients had Na < 135 mmol/L at 24 h. The two fluids had different effects on respiratory and post-operative situations. CONCLUSIONS: The use of saline 0.9% was associated with a lower incidence of electrolyte disturbances.

  7. Quantum random number generators

    Science.gov (United States)

    Herrero-Collantes, Miguel; Garcia-Escartin, Juan Carlos

    2017-01-01

    Random numbers are a fundamental resource in science and engineering with important applications in simulation and cryptography. The inherent randomness at the core of quantum mechanics makes quantum systems a perfect source of entropy. Quantum random number generation is one of the most mature quantum technologies with many alternative generation methods. This review discusses the different technologies in quantum random number generation from the early devices based on radioactive decay to the multiple ways to use the quantum states of light to gather entropy from a quantum origin. Randomness extraction and amplification and the notable possibility of generating trusted random numbers even with untrusted hardware using device-independent generation protocols are also discussed.

  8. Random Differential Privacy

    OpenAIRE

    Hall, Rob; Rinaldo, Alessandro; Wasserman, Larry

    2011-01-01

    We propose a relaxed privacy definition called {\\em random differential privacy} (RDP). Differential privacy requires that adding any new observation to a database will have small effect on the output of the data-release procedure. Random differential privacy requires that adding a {\\em randomly drawn new observation} to a database will have small effect on the output. We show an analog of the composition property of differentially private procedures which applies to our new definition. We sh...

  9. Home visit improves knowledge, self-care and adhesion in heart failure: randomized Clinical Trial HELEN-I Visita domiciliar mejora conocimiento, auto cuidado, adhesión en la insuficiencia cardíaca: Ensayo Clínico Aleatorizado HELEN - I Visita domiciliar melhora conhecimento, autocuidado e adesão na insuficiência cardíaca: ensaio clínico randomizado HELEN-I

    Directory of Open Access Journals (Sweden)

    Cláudia Motta Mussi

    2013-02-01

    Full Text Available OBJECTIVE: To verify the effect of an educative nursing intervention composed of home visits and phone calls on patients' knowledge about the disease, self-care and adhesion to the treatment. METHODS: Randomized clinical trial with patients with recent hospitalization caused by decompensated heart failure. There were two groups: the intervention group, which has received four home visits and four phone calls to reinforce the guidelines during six months of follow up; and the control group, which has received conventional follow up with no visits or phone calls. RESULTS: Two hundred patients were randomized (101 in the intervention group and 99 in the control group. After six months, a significant improvement was observed in self-care and knowledge about the disease in the intervention group (P=0.001 and POBJETIVO: Verificar el efecto de una intervención educativa de enfermería combinada de visita domiciliaria y contacto telefónico en pacientes con internación reciente por insuficiencia cardiaca descompensada, en el conocimiento de la enfermedad, las habilidades para el autocuidado y la adhesión al tratamiento comparado con el acompañamiento convencional de pacientes en el período de seis meses. MÉTODOS: Ensayo Clínico Aleatorizado en pacientes que fueron ingresados recientemente por insuficiencia cardiaca descompensada. El grupo intervención recibió cuatro visitas domiciliarias y cuatro contactos telefónicos para reforzar las orientaciones en seis meses de acompañamiento; el grupo control recibió acompañamiento convencional sin visitas y sin contactos telefónicos. RESULTADOS: Fueron aleatorizados doscientos pacientes (101: intervención y 99: control. Tras seis meses, se observó una mejoría significativa en el conocimiento y el autocuidado para el grupo intervención (P=0,001 y POBJETIVO: verificar o efeito de uma intervenção educativa de enfermagem combinada, caracterizada por visita domiciliar e contato telefônico, em

  10. Eletrocauterio na cesarea : complicações na ferida cirurgica

    OpenAIRE

    Cristiane Menabo Moreira

    2010-01-01

    Resumo: Objetivo: Avaliar a efetividade e segurança do uso do eletrocautério para coagulação na da ferida operatória da cesárea. Métodos: Foi realizado um ensaio clínico piloto duplo cego controlado aleatorizado. Mulheres com indicação de cesárea, com até uma cesárea prévia, que fizeram pré-natal foram aleatorizadas na hora da cirurgia para uso ou não de eletrocautério para coagulação. As 224 voluntárias que participaram foram examinadas na alta hospitalar (3o dia) e pós-alta, no 7°.ao 10° di...

  11. Random errors revisited

    DEFF Research Database (Denmark)

    Jacobsen, Finn

    2000-01-01

    the random errors of estimates of the sound intensity in, say, one-third octave bands from the power and cross power spectra of the signals from an intensity probe determined with a dual channel FFT analyser. This is not very practical, though. In this paper it is demonstrated that one can predict the random...

  12. a randomized controlled trial.

    African Journals Online (AJOL)

    milk, only an estimated one -fourth of neonates in India were breastfed within ... standard of care in India and mothers are informed about. 6 months of ... weeks postpartum. A random number sequence was generated using a com- puter program. Block randomization was used with a fixed block size of four. Concealment of ...

  13. Hashing, Randomness and Dictionaries

    DEFF Research Database (Denmark)

    Pagh, Rasmus

    time and memory space. To some extent we also consider lower bounds, i.e., we attempt to show limitations on how efficient algorithms are possible. A central theme in the thesis is randomness. Randomized algorithms play an important role, in particular through the key technique of hashing. Additionally...

  14. Random Walks and Trees

    Directory of Open Access Journals (Sweden)

    Shi Zhan

    2011-03-01

    Full Text Available These notes provide an elementary and self-contained introduction to branching random walks. Section 1 gives a brief overview of Galton–Watson trees, whereas Section 2 presents the classical law of large numbers for branching random walks. These two short sections are not exactly indispensable, but they introduce the idea of using size-biased trees, thus giving motivations and an avant-goût to the main part, Section 3, where branching random walks are studied from a deeper point of view, and are connected to the model of directed polymers on a tree. Tree-related random processes form a rich and exciting research subject. These notes cover only special topics. For a general account, we refer to the St-Flour lecture notes of Peres [47] and to the forthcoming book of Lyons and Peres [42], as well as to Duquesne and Le Gall [23] and Le Gall [37] for continuous random trees.

  15. ChPT tests at NA48 and NA62

    Directory of Open Access Journals (Sweden)

    Gonnella Francesco

    2014-01-01

    Full Text Available Final results from an analysis of about 400 K± → π±γγ rare decay candidates collected by the NA48/2 and NA62 experiments at CERN during low intensity runs with minimum bias trigger configurations are presented. The results include a model-independent decay rate measurement and fits to Chiral Perturbation Theory (ChPT description. The data support the ChPT prediction for a cusp in the di-photon invariant mass spectrum at the two pion threshold.

  16. Corpo e sexualidade na gravidez

    Directory of Open Access Journals (Sweden)

    Natalúcia Matos Araújo

    2012-06-01

    Full Text Available Estudo etnográfico que teve como objetivo compreender como as gestantes vivenciam os processos fisiológicos do seu corpo durante a gestação e a sua repercussão na sexualidade. A pesquisa envolveu sete mulheres residentes em bairro popular de São Paulo. Na coleta de dados, utilizou-se observação participante e entrevista com questões norteadoras. Os dados foram apresentados na forma de narrativa e posteriormente organizados nas categorias: Percebendo as transformações corporais; Convivendo com as mudanças no corpo; Sentimentos e sensações na vida sexual durante a gestação e imaginando o corpo e a sexualidade após a gestação. As mulheres referiram-se às transformações do corpo como desconfortos e expressaram a preocupação de que fossem definitivas. Expressaram o desejo de que, após o parto, o corpo volte a ser como era e que volte a sentir desejo sexual. O reconhecimento destes fatos constitui-se numa ferramenta primordial na adequação das práticas profissionais.

  17. All new for NA62

    CERN Multimedia

    Antonella Del Rosso

    2012-01-01

    This week sees the start of the first run of the new NA62 experiment. This will be a unique opportunity for the collaboration to test its new beam, new detectors and new data acquisition system before the physics run in 2014. Speaking to the Bulletin, the NA62 technical coordinator Ferdinand Hahn shares the many challenges that the various teams faced to be on time for beam. Ready, steady, start!   A Large Angle Veto detector (white) in place in the NA62 decay volume (blue). With components from almost all the detectors in place downstream of the decay point of the mother particles – the kaons – and of the KTAG detector that tags the kaons before they decay, NA62 is ready for its first technical run. This unique run will test all the equipment as well as the trigger and the data acquisition systems. “This year, we will have about five weeks of beam from the SPS before the long shutdown of all the CERN machines,” says Ferdinand Hahn, NA62 Technical Co-...

  18. Autonomous Byte Stream Randomizer

    Science.gov (United States)

    Paloulian, George K.; Woo, Simon S.; Chow, Edward T.

    2013-01-01

    Net-centric networking environments are often faced with limited resources and must utilize bandwidth as efficiently as possible. In networking environments that span wide areas, the data transmission has to be efficient without any redundant or exuberant metadata. The Autonomous Byte Stream Randomizer software provides an extra level of security on top of existing data encryption methods. Randomizing the data s byte stream adds an extra layer to existing data protection methods, thus making it harder for an attacker to decrypt protected data. Based on a generated crypto-graphically secure random seed, a random sequence of numbers is used to intelligently and efficiently swap the organization of bytes in data using the unbiased and memory-efficient in-place Fisher-Yates shuffle method. Swapping bytes and reorganizing the crucial structure of the byte data renders the data file unreadable and leaves the data in a deconstructed state. This deconstruction adds an extra level of security requiring the byte stream to be reconstructed with the random seed in order to be readable. Once the data byte stream has been randomized, the software enables the data to be distributed to N nodes in an environment. Each piece of the data in randomized and distributed form is a separate entity unreadable on its own right, but when combined with all N pieces, is able to be reconstructed back to one. Reconstruction requires possession of the key used for randomizing the bytes, leading to the generation of the same cryptographically secure random sequence of numbers used to randomize the data. This software is a cornerstone capability possessing the ability to generate the same cryptographically secure sequence on different machines and time intervals, thus allowing this software to be used more heavily in net-centric environments where data transfer bandwidth is limited.

  19. gigapanorama of NA 62 cavern

    CERN Multimedia

    Brice, Maximilien

    2015-01-01

    The image shows the new rare Kaon decay experiment at CERN, called NA62. The NA62 experiment is 270 metres long and includes a 120-metre-long vacuum tank, shown here, housing several of the particle detectors. (Note: the experiment axis is a straight line, the curving of the tank is an optical effect of the photo.) Kaons are particles that decay into lighter elementary particles. The kaon decay processes are mostly well known, except for some very rare decay modes. For example, NA62 is investigating a rare decay predicted by the Standard Model in which a kaon decays into one pion and two neutrinos. This process occurs only once every 10 billion decays. The understanding of such ultra-rare decays are of great importance because they test the Standard Model in energy ranges not accessible by direct measurements. They are therefore complementary to the measurements at the LHC. ultra high definition on demand (photolab@cern.ch).

  20. Alcool e drogas na esquizofrenia

    OpenAIRE

    Marilia Montoya Boscolo

    2000-01-01

    Resumo: O objetivo deste trabalho é estudar o fenômeno do uso de álcool e drogas ilícitas (maconha e cocaína) na esquizoftenia. Trata-se de estudo comparativo, casocontrole, de dois grupos de esquizoftênicos pareados para sexo e idade, que preencheram os critérios diagnósticos do DSMIV para esquizoftenia. O grupo caso é definido por esquizofrênicos que têm história de ter feito uso de álcool, pelo menos no último mês e/ ou história de ter feito uso de drogas (maconha e cocaína), pelo menos al...

  1. OGLAŠEVANJE NA FACEBOOKU

    OpenAIRE

    Renko, Katica

    2013-01-01

    V magistrskem delu smo se seznanili z oglaševanjem na Facebooku. S pregledom gradiva, ki nam je ponujeno, smo preverili pogoje, načine, oblike … oglaševanja, ki pa smo jih s pregledom situacije v praksi preverili in dopolnili. Ob zaključku dela lahko rečemo, da je oglaševanje preko FB enostavnejše, cenejše, dostopnejše, omogoča nam ažurnost in samo komunikacijo z naslovniki, ki so potencialni kupci naših ponudb. Množični mediji nam omogočajo mnogotero obliko oglaševanja. Izbrana oblika ponuja...

  2. HERKUL NA BRAČU

    OpenAIRE

    Cambi, Nenad

    2013-01-01

    U radu se raspravlja o reljefu Herkula uklesanom u litici pred ulazom u kamenolomu Rasohe. Figure uklesane u stijeni su kultni reljefi božanstva koje se časti u prirodnom okruženju. Herkulov reljef je kultna slika na ulazu u kamenolom pred kojim su se prinosile žrtve na kamenom žrtveniku. Također se raspravlja o natpisu sa žrtvenika posvećenom Herkulu iz kamenoloma Stražišće i donosi ispravak pogrešnog čitanja natpisa. Donose se i drugi nalazi iz kamenoloma Dalmcije koji ...

  3. Random maintenance policies

    CERN Document Server

    Nakagawa, Toshio

    2014-01-01

    Exploring random maintenance models, this book provides an introduction to the implementation of random maintenance, and it is one of the first books to be written on this subject.  It aims to help readers learn new techniques for applying random policies to actual reliability models, and it provides new theoretical analyses of various models including classical replacement, preventive maintenance and inspection policies. These policies are applied to scheduling problems, backup policies of database systems, maintenance policies of cumulative damage models, and reliability of random redundant systems. Reliability theory is a major concern for engineers and managers, and in light of Japan’s recent earthquake, the reliability of large-scale systems has increased in importance. This also highlights the need for a new notion of maintenance and reliability theory, and how this can practically be applied to systems. Providing an essential guide for engineers and managers specializing in reliability maintenance a...

  4. Drawing a random number

    DEFF Research Database (Denmark)

    Wanscher, Jørgen Bundgaard; Sørensen, Majken Vildrik

    2006-01-01

    highly uniform multidimensional draws, which are highly relevant for todays traffic models. This paper shows among others combined shuffling and scrambling seems needless, that scrambling gives the lowest correlation and that there are detectable differences between random numbers, dependent...

  5. Theory of random sets

    CERN Document Server

    Molchanov, Ilya

    2017-01-01

    This monograph, now in a thoroughly revised second edition, offers the latest research on random sets. It has been extended to include substantial developments achieved since 2005, some of them motivated by applications of random sets to econometrics and finance. The present volume builds on the foundations laid by Matheron and others, including the vast advances in stochastic geometry, probability theory, set-valued analysis, and statistical inference. It shows the various interdisciplinary relationships of random set theory within other parts of mathematics, and at the same time fixes terminology and notation that often vary in the literature, establishing it as a natural part of modern probability theory and providing a platform for future development. It is completely self-contained, systematic and exhaustive, with the full proofs that are necessary to gain insight. Aimed at research level, Theory of Random Sets will be an invaluable reference for probabilists; mathematicians working in convex and integ...

  6. NA60 frees the quarks

    CERN Multimedia

    2003-01-01

    Fitted with new state-of-the-art silicon detectors, NA60 is prepared to study the phase transition from confined hadronic matter to a deconfined (free) quark-gluon plasma, a state of matter which probably existed an instant after the Big Bang.

  7. NA62: Hidden Sector Physics

    CERN Document Server

    Cesarotti, Carissa Joyce

    2016-01-01

    Modern experimental physics is often probing for new physics by either finding deviations from predictions on extremely precise measurements, or by looking for a new signal that cannot be explained with existing models. The NA62 experiment at CERN does the former by measuring the ultra-rare decay $K^+ \\rightarrow \\pi^+ \

  8. EMC anténa

    OpenAIRE

    Tenora, Jan

    2016-01-01

    Cílem této diplomové práce bylo navrhnout anténu pracující ve frekvenčním pásmu 30 MHz až 1 GHz. Navržená bikónická anténa vyžaduje ke správné funkci symetrické napájení, proto bylo dále nutné navrhnout vhodný symetrizační člen sestavený z diskrétních součástek. Navržená anténa byla také zkonstruována a měřením byl ověřen její činitel odrazu na vstupu, zisk a směrové charakteristiky. Tato diplomová práce dále obsahuje seznámení čtenáře s principy měření úrovně rušivých signálů v oblasti EMC p...

  9. Quasiclassical Random Matrix Theory

    OpenAIRE

    Prange, R. E.

    1996-01-01

    We directly combine ideas of the quasiclassical approximation with random matrix theory and apply them to the study of the spectrum, in particular to the two-level correlator. Bogomolny's transfer operator T, quasiclassically an NxN unitary matrix, is considered to be a random matrix. Rather than rejecting all knowledge of the system, except for its symmetry, [as with Dyson's circular unitary ensemble], we choose an ensemble which incorporates the knowledge of the shortest periodic orbits, th...

  10. Quantum randomness and unpredictability

    Energy Technology Data Exchange (ETDEWEB)

    Jaeger, Gregg [Quantum Communication and Measurement Laboratory, Department of Electrical and Computer Engineering and Division of Natural Science and Mathematics, Boston University, Boston, MA (United States)

    2017-06-15

    Quantum mechanics is a physical theory supplying probabilities corresponding to expectation values for measurement outcomes. Indeed, its formalism can be constructed with measurement as a fundamental process, as was done by Schwinger, provided that individual measurements outcomes occur in a random way. The randomness appearing in quantum mechanics, as with other forms of randomness, has often been considered equivalent to a form of indeterminism. Here, it is argued that quantum randomness should instead be understood as a form of unpredictability because, amongst other things, indeterminism is not a necessary condition for randomness. For concreteness, an explication of the randomness of quantum mechanics as the unpredictability of quantum measurement outcomes is provided. Finally, it is shown how this view can be combined with the recently introduced view that the very appearance of individual quantum measurement outcomes can be grounded in the Plenitude principle of Leibniz, a principle variants of which have been utilized in physics by Dirac and Gell-Mann in relation to the fundamental processes. This move provides further support to Schwinger's ''symbolic'' derivation of quantum mechanics from measurement. (copyright 2016 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  11. Effects of NaCl stress on seed germination, early seedling growth ...

    African Journals Online (AJOL)

    Effects of salt stress on seed germination, early seedling growth and some physiological characteristics were evaluated for four cauliflower species in seven treatments of salinity including 0 (control), 34, 68, 102, 136, 170 and 204 mM NaCl in a three replicated randomized completely block design (RCBD). This result shows ...

  12. Enzalutamide in Men with Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer

    DEFF Research Database (Denmark)

    Beer, Tomasz M; Armstrong, Andrew J; Rathkopf, Dana

    2017-01-01

    Enzalutamide significantly improved radiographic progression-free survival (rPFS) and overall survival (OS) among men with chemotherapy-naïve metastatic castration-resistant prostate cancer at the prespecified interim analysis of PREVAIL, a phase 3, double-blind, randomized study. We evaluated...

  13. Never Send an Infantryman Where You Can Send an Artillery Shell.

    Science.gov (United States)

    1980-06-01

    for his own plane to take the division commander to either London or Paris. Upon his return the division commander told Simpson that he had not... Palatinate region south of the Moselle and to crossing the Rhine in his sector, Simpson continued to make ready for PLUNDER. 77 On the other side of the

  14. Photodesorption of Na atoms from rough Na surfaces

    DEFF Research Database (Denmark)

    Balzer, Frank; Gerlach, R.; Manson, J.R.

    1997-01-01

    We investigate the desorption of Na atoms from large Na clusters deposited on dielectric surfaces. High-resolution translational energy distributions of the desorbing atoms are determined by three independent methods, two-photon laser-induced fluorescence, as well as single-photon and resonance......-enhanced two-photon ionization techniques. Upon variation of surface temperature and for different substrates (mica vs lithium fluoride) clear non-Maxwellian time-of-flight distributions are observed with a cos θ angular dependence and most probable kinetic energies below that expected of atoms desorbing from...... atoms are scattered by surface vibrations. Recent experiments providing time constants for the decay of the optical excitations in the clusters support this model. The excellent agreement between experiment and theory indicates the importance of both absorption of the laser photons via direct excitation...

  15. Economia na consulta de Endodontia

    OpenAIRE

    Pinto, Diogo Filipe Cardoso

    2016-01-01

    Introdução: Em Portugal a realidade actual, clínica e financeira do exercício da Medicina Dentária é bem distinta da do final do séc. XX devido à pletora de Médicos Dentistas e à baixa de honorários por acto Médico registada nos últimos anos. Objectivos: Este trabalho teve como objectivo perceber um pouco sobre os detalhes a ter em consideração aquando da abertura de uma clínica centrada na realização de tratamentos na área da Endodontia, e como publicitá-la de forma legal e apelativa. Pre...

  16. ULIČNA LUTKOVNA PREDSTAVA

    OpenAIRE

    Novak, Natalija

    2016-01-01

    V diplomski nalogi z naslovom Ulična lutkovna predstava je predstavljena priprava in izvedba gledališko-lutkovne predstave, ki smo jo izvedli v okviru programa Šole uličnega gledališča, pod vodstvom gledališča Ane Monro. V teoretičnem delu smo na podlagi strokovne literature predstavili dejavnost uličnega gledališča, njegove zvrsti, vlogo prostora in publike v uličnem gledališču ter kratko zgodovino le-tega. Predstavili smo tudi gledališče Ane Monro, ki je glavni organizator Šole uličnega ...

  17. Carne suína

    OpenAIRE

    Ortigara, Claudino

    2000-01-01

    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. A carne suína é a fonte de proteína animal mais consumida no mundo. No entanto, em muitos países e em especial no Brasil o consumo per capita é muito baixo. Como conseqüência disso, limita-se o crescimento do segmento produtivo e uma série de benefícios socioeconômicos que são gerados pela atividade suinocultura.Com esse trabalho, buscamos uma explicação para entender a resistência da população ao consum...

  18. NA64 Status Report 2017

    CERN Document Server

    Gninenko, Sergei

    2017-01-01

    The experiment NA64 is aimed at a direct search for invisible decays of sub-GeV dark photons (A′). The main goal in 2016 was to probe a region of the A′ parameter space, particularly interesting for the explanation of the muon g − 2 anomaly. The status and results from two NA64 runs in July and October 2016, obtained, respectively, with 2.75×109 and 4×1010 accumulated electron on target are reported. A feasibility study of the search for the X → e+e− decay of a new light X boson, which could explain a recently observed excess of e+e− events from excited 8Be transitions is also presented.

  19. Survey Email Scheduling and Monitoring in eRCTs (SESAMe): A Digital Tool to Improve Data Collection in Randomized Controlled Clinical Trials.

    Science.gov (United States)

    Skonnord, Trygve; Steen, Finn; Skjeie, Holgeir; Fetveit, Arne; Brekke, Mette; Klovning, Atle

    2016-11-22

    Electronic questionnaires can ease data collection in randomized controlled trials (RCTs) in clinical practice. We found no existing software that could automate the sending of emails to participants enrolled into an RCT at different study participant inclusion time points. Our aim was to develop suitable software to facilitate data collection in an ongoing multicenter RCT of low back pain (the Acuback study). For the Acuback study, we determined that we would need to send a total of 5130 emails to 270 patients recruited at different centers and at 19 different time points. The first version of the software was tested in a pilot study in November 2013 but was unable to deliver multiuser or Web-based access. We resolved these shortcomings in the next version, which we tested on the Web in February 2014. Our new version was able to schedule and send the required emails in the full-scale Acuback trial that started in March 2014. The system architecture evolved through an iterative, inductive process between the project study leader and the software programmer. The program was tested and updated when errors occurred. To evaluate the development of the software, we used a logbook, a research assistant dialogue, and Acuback trial participant queries. We have developed a Web-based app, Survey Email Scheduling and Monitoring in eRCTs (SESAMe), that monitors responses in electronic surveys and sends reminders by emails or text messages (short message service, SMS) to participants. The overall response rate for the 19 surveys in the Acuback study increased from 76.4% (655/857) before we introduced reminders to 93.11% (1149/1234) after the new function (Pstorage. The SESAMe software facilitates consecutive patient data collection in RCTs and can be used to increase response rates and quality of research, both in general practice and in other clinical trial settings.

  20. Perseveración en la tarea de generación aleatoria de números para niños = Perseveração na tarefa geração aleatória de números para crianças = Perseveration in random number generation task for children

    Directory of Open Access Journals (Sweden)

    Wilson, Maximiliano A.

    2014-01-01

    Full Text Available Observam-se déficits inibitórios em vários quadros neurológicos e psiquiátricos, podendo aumentar a frequência de respostas perseverativas. Não há uma padronização dos critérios para avaliar a perseveração. O estudo 1 visou a obter dados preliminares de até quantas casas a repetição de um número pode ser considerada uma perseveração na tarefa Geração Aleatória de Números (GAN. O potencial discriminativo dos pontos de corte foi investigado pela comparação entre TDAH e saudáveis (Estudo 2. Os instrumentos foram: questionário de dados sociodemográficos e de saúde, Questionário Abreviado de Conners, Matrizes Progressivas Coloridas de Raven e o GAN. Participaram crianças com idades de 6 a 12 anos (Estudo 1: n= 60; Estudo 2: transtorno de déficit de atenção/hiperatividade (TDAH, n=9 e controles, n=18. As crianças levaram em média 4,97 (dp=1,78 caselas para repetir um número. O critério que considera perseveração como a repetição de um número até cinco caselas após a sua última evocação diferenciou TDAH de controles. Portanto, esse parece ser o critério mais sensível para avaliar a perseveração

  1. Coded Random Access

    DEFF Research Database (Denmark)

    Paolini, Enrico; Stefanovic, Cedomir; Liva, Gianluigi

    2015-01-01

    , in which the structure of the access protocol can be mapped to a structure of an erasure-correcting code defined on graph. This opens the possibility to use coding theory and tools for designing efficient random access protocols, offering markedly better performance than ALOHA. Several instances of coded......The rise of machine-to-machine communications has rekindled the interest in random access protocols as a support for a massive number of uncoordinatedly transmitting devices. The legacy ALOHA approach is developed under a collision model, where slots containing collided packets are considered...... as waste. However, if the common receiver (e.g., base station) is capable to store the collision slots and use them in a transmission recovery process based on successive interference cancellation, the design space for access protocols is radically expanded. We present the paradigm of coded random access...

  2. Persistência na lactação para vacas da raça Holandesa criadas no Estado do Rio Grande do Sul via modelos de regressão aleatória Lactation persistency for Holstein cows raised in the State of Rio Grande do Sul using a random regression model

    Directory of Open Access Journals (Sweden)

    Cristian Kelen Pinto Dorneles

    2009-08-01

    Full Text Available Foram utilizados 21.702 registros de produção de leite no dia do controle de 2.429 vacas primíparas da raça Holandesa, filhas de 233 touros, coletados em 33 rebanhos do Estado do Rio Grande do Sul, entre 1992 e 2003, para estimar parâmetros genéticos, para três medidas de persistência (PS1, PS2 e PS3 e para a produção de leite até 305 dias (P305 de lactação. Os modelos de regressão aleatória ajustados aos controles leiteiros entre o sexto e o 300o dia de lactação incluíram o efeito de rebanho-ano-mês do controle, a idade da vaca ao parto e os parâmetros do polinômio de Legendre de ordem quatro, para modelar a curva média da produção de leite da população e os parâmetros do mesmo polinômio, para modelar os efeitos aleatórios genético-aditivo direto e de ambiente permanente. As estimativas de herdabilidade obtidas foram 0,05, 0,08 e 0,19, respectivamente, para PS1, PS2 e PS3 e 0,25, para P305 sugerindo a possibilidade de ganho genético por meio da seleção para PS3 e para P305. As correlações genéticas entre as três medidas de persistência e P305, variaram de -0,05 a 0,07, indicando serem persistência e produção, características determinadas por grupos de genes diferentes. Assim, consequentemente, a seleção para P305, geralmente praticada, não promove progresso genético para a persistência.There were used 21,702 test day milk yields from 2,429 first parity Holstein breed cows, daughters of 2,031 dams and 233 sires, distributed over 33 herds in the state of Rio Grande do Sul, from 1992 to 2003. Genetic parameters for three measures of lactation persistency (PS1, PS2 e PS3 and for milk production to 305 days (P305 were evaluated. A random regression model adjusted by fourth order Legendre polynomial was used. The random regression model adjusted to test day between the sixth and the 305th lactation day included the herd-year-season of the test day, the age of the cow at the parturition effects and the

  3. NA

    OpenAIRE

    Gleeson, David A.

    1998-01-01

    With advancements in the fields of propulsion, aerodynamics, structures, materials and controls, the routine exploration of hypersonic, atmospheric flight has become a more feasible concept. Thus, there is a need for efficient and effective hypersonic configurations. Current studies in configuration efficiency and effectiveness seem to be concentrated in aircraft subsystem design, especially propulsion systems, rather than at the conceptual aircraft system design level. This thesis attempts t...

  4. Sequential Phase 1 and Phase 2 randomized, controlled trials of the safety, immunogenicity and efficacy of combined pre-erythrocytic vaccine antigens RTS,S and TRAP formulated with AS02 Adjuvant System in healthy, malaria naïve adults.

    Science.gov (United States)

    Kester, Kent E; Gray Heppner, D; Moris, Philippe; Ofori-Anyinam, Opokua; Krzych, Urszula; Tornieporth, Nadia; McKinney, Denise; Delchambre, Martine; Ockenhouse, Christian F; Voss, Gerald; Holland, Carolyn; Beckey, Jolie Palensky; Ballou, W Ripley; Cohen, Joe

    2014-11-20

    In an attempt to improve the efficacy of the candidate malaria vaccine RTS,S/AS02, two studies were conducted in 1999 in healthy volunteers of RTS,S/AS02 in combination with recombinant Plasmodium falciparum thrombospondin-related anonymous protein (TRAP). In a Phase 1 safety and immunogenicity study, volunteers were randomized to receive TRAP/AS02 (N=10), RTS,S/AS02 (N=10), or RTS,S+TRAP/AS02 (N=20) at 0, 1 and 6-months. In a Phase 2 challenge study, subjects were randomized to receive either RTS,S+TRAP/AS02 (N=25) or TRAP/AS02 (N=10) at 0 and 1-month, or to a challenge control group (N=8). In both studies, the combination vaccine had an acceptable safety profile and was acceptably tolerated. Antigen-specific antibodies, lymphoproliferative responses, and IFN-γ production by ELISPOT assay elicited with the combination vaccine were qualitatively similar to those generated by the single component vaccines. However, post-dose 2 anti-CS antibodies in the RTS,S+TRAP/AS02 vaccine recipients were lower than in the RTS,S/AS02 vaccine recipients. After challenge, 10 of 11 RTS,S+TRAP/AS02 vaccinees, 5 of 5 TRAP/AS02 vaccinees, and 8 of 8 infectivity controls developed parasitemia, with median pre-patent periods of 13.0, 11.0, and 12.0 days, respectively. The absence of any prevention or delay of parasitemia by TRAP/AS02 suggests no apparent added value of TRAP/AS02 as a candidate vaccine. The absence of significant protection or delay of parasitemia in the 11 RTS,S+TRAP/AS02 vaccine recipients contrasts with previous 2 dose studies of RTS,S/AS02. The small sample size did not permit identifying statistically significant differences between the study arms. However, we speculate, within the constraints of the challenge study, that the presence of the TRAP antigen may have interfered with the vaccine efficacy previously observed with this regimen of RTS,S/AS02, and that any future TRAP-based vaccines should consider employing alternative vaccine platforms. Copyright © 2014

  5. A discrete fractional random transform

    OpenAIRE

    Liu, Zhengjun; Zhao, Haifa; Liu, Shutian

    2006-01-01

    We propose a discrete fractional random transform based on a generalization of the discrete fractional Fourier transform with an intrinsic randomness. Such discrete fractional random transform inheres excellent mathematical properties of the fractional Fourier transform along with some fantastic features of its own. As a primary application, the discrete fractional random transform has been used for image encryption and decryption.

  6. Diffusion of propylene adsorbed in Na-Y and Na-ZSM5 zeolites ...

    Indian Academy of Sciences (India)

    Here we report the quasielastic neutron scattering and FTIR studies on the dynamics of propylene adsorbed in Na-Y and Na-ZSM5 zeolites. QENS data show that although the mechanism of translational motion of propylene is jump diffusion in both the cases of Na-Y and Na-ZSM5 zeolites, the diffusivity is affected by the ...

  7. Diffusion of propylene adsorbed in Na-Y and Na-ZSM5 zeolites ...

    Indian Academy of Sciences (India)

    Abstract. Here we report the quasielastic neutron scattering and FTIR studies on the dynamics of propylene adsorbed in Na-Y and Na-ZSM5 zeolites. QENS data show that although the mechanism of translational motion of propylene is jump diffusion in both the cases of Na-Y and Na-ZSM5 zeolites, the diffusivity is affected ...

  8. Na+,K+-ATPase Na+ affinity in rat skeletal muscle fiber types

    DEFF Research Database (Denmark)

    Kristensen, Michael; Juel, Carsten

    2010-01-01

    Previous studies in expression systems have found different ion activation of the Na(+)/K(+)-ATPase isozymes, which suggest that different muscles have different ion affinities. The rate of ATP hydrolysis was used to quantify Na(+),K(+)-ATPase activity, and the Na(+) affinity of Na(+),K(+)-ATPase...

  9. Alkalinizing effect of NaHCO₃ with and without glucose when administered orally to euhydrated neonatal dairy calves.

    Science.gov (United States)

    Grünberg, W; Hartmann, H; Arlt, S; Burfeind, O; Staufenbiel, R

    2013-06-01

    The use of oral rehydration solutions (ORS) is well established as an effective treatment to correct water-, electrolyte-, and acid-base balance in diarrheic calves. The main ingredients of a commercial ORS are Na, glucose, and alkalinizing agents, such as NaHCO3. Particular importance is attributed to the combination of glucose and Na at a specific ratio to optimize intestinal sodium, and thereby water uptake, through the sodium-glucose co-transport. Enhancing intestinal Na absorption by combining glucose and Na in an ORS has the potential to improve the alkalinizing effect of an ORS according the strong ion theory. The objective of this study was to investigate the effect of glucose on the alkalinizing effect of NaHCO3 when administered orally. Nine healthy neonatal Holstein-Friesian calves underwent 3 oral treatments with 2-L solutions of NaHCO3 (150 mmol/L), glucose (300 mmol/L), and glucose + NaHCO3 (300 mmol/L + 150 mmol/L, respectively) in randomized order. Arterial and venous blood was obtained before treatment and in 30-min intervals thereafter for blood gas analysis and determination of plasma protein and electrolyte concentrations. Urine was collected volumetrically to determine urine volume, osmolality, pH, net acid excretion, and renal Na excretion after treatment. Plasma volume changes were extrapolated from plasma protein concentration changes. Treatment and time effects were tested with repeated measures ANOVA. Only subtle differences between oral administration of NaHCO3, with and without glucose, were observed for the change of the standard HCO3 concentration relative to baseline. No differences in plasma Na, plasma volume expansion, renal Na, net base excretion, urine volume, or pH could be identified between animals treated orally with NaHCO3 with and without glucose. Similarly, no differences in blood glucose concentration, plasma volume expansion, urine volume, or renal glucose excretion were observed in the 8h after treatment when comparing

  10. Identification of binding domains in the sodium channel Na(V)1.8 intracellular N-terminal region and annexin II light chain p11.

    Science.gov (United States)

    Poon, W-Y Louisa; Malik-Hall, Misbah; Wood, John N; Okuse, Kenji

    2004-01-30

    The interaction of p11 (annexin II light chain) with the N-terminal domain of Na(V)1.8, a tetrodotoxin-resistant sodium channel, is essential for the functional expression of the channel. Here we show that p11 binds to Na(V)1.8 but not to sodium channel isoforms Na(V)1.2, 1.5, 1.7 or Na(V)1.9. The binding of amino acids 74-103 of Na(V)1.8 to p11 residues 33-78 occurs in a random coiled region flanked by two EF hand motifs whose crystal structure has been established. As Na(V)1.8 channel expression is associated with pain pathways, drugs that disrupt the Na(V)1.8-p11 interaction and down-regulate channel expression may have analgesic activity.

  11. Dijagnostičko-terapijski pristup pacijentu sa sumnjom na alergiju na penicilin

    OpenAIRE

    Stanić Benić, Mirjana; Vlahović-Palčvevski, Vera

    2016-01-01

    Iako se ne zna točna učestalost alergije na lijekove, pripisuje joj se oko 1/10 svih neželjenih reakcija na lijekove. Neželjene reakcije na penicilin javljaju se u 0,7 – 10 % ljudi koji primaju penicilin. Stvarna učestalost alergije na penicilin još je manja, budući da su se u prošlosti mnoge nealergijske nuspojave antibiotika pripisivale alergiji. U pacijenata kod kojih postoji sumnja na alergiju na penicilin važno je utvrditi alergološki status. Nepotrebno izbjegavanje upotrebe penicilina, ...

  12. Crowdsourcing: impactos na performance na venda de produtos

    OpenAIRE

    Alves, Milton Ruiz Rodrigues

    2015-01-01

    Vivemos num momento em que as expectativas de pensadores como Lévy (1998), se concretizaram. O consumidor mudou, passou a exigir um diálogo entre a empresa e a sociedade. Esse novo cenário cobrou da tecnologia formas de aperfeiçoar e agilizar este processo de comunicação, plataformas baseadas na internet que propiciem e incentivam a troca de informações. Nesta esfera surgiu o crowdsourcing, com a disponibilização do capital intelectual das massas, que acabou por mudar a form...

  13. As atitudes do terapeuta na teoria centrada na pessoa

    OpenAIRE

    Carreteiro, Tereza Cristina Othenio Cordeiro

    1981-01-01

    Este trabalho procede a um exame arqueológico das atitudes terapêuticas ao longo do desenvolvimento da teoria Rogeriana. Estuda-se o processo evolutivo que compõe o referido corpo teórico. Inicialmente, é feita uma breve apresentação de Carl Rogers, precursor da Abordagem Centrada na Pessoa. São discorridos aspectos pessoais e profissionais do autor assim como suas principais contribuições no campo da Psicologia clínica. A teoria é decomposta em três fases principais: pré história da empat...

  14. Priklop perifernih naprav na Raspberry Pi

    OpenAIRE

    Fabčič, Simon

    2015-01-01

    Moje diplomsko delo obravnava povezovanje perifernih naprav na Raspberry Pi. Najprej je predstavljena oprema, ki sem jo potreboval pri pisanju. Kot glavno strojno opremo sem uporabil enoploščni računalnik Raspberry Pi (model B) in nanj namestil operacijski sistem Raspbian. Na njem je bilo že pred naloženo razvojno okolje za programski jezik Python, ki sem ga tudi uporabljal. Nato sem prikazal, kako na Raspberry Pi na različne načine in prek raznih protokolov povežemo periferne naprave ter dig...

  15. Upravnopravna regulacija prava na pristup informacijama

    OpenAIRE

    Basta, Đurđica

    2016-01-01

    Pravo na pristup informacijama čini jedan od ključnih elemenata informacijskoga upravnog prava. U većini zemalja, uključujući Hrvatsku, pravo na pristup informacijama javnog sektora relativno je novo pravo. Uz Ustav RH kao temeljni dokument, od ožujka 2013. na snazi je novi, drugi hrvatski Zakon o pravu na pristup informacijama. Kritike na račun pravnog okvira kao i institucionalne podrške njegovoj provedbi doveli su do izmjena Zakona 2010. odnosno 2011., a 2013. i do donošenja...

  16. Random regression models

    African Journals Online (AJOL)

    zlukovi

    modelled as a quadratic regression, nested within parity. The previous lactation length was ... This proportion was mainly covered by linear and quadratic coefficients. Results suggest that RRM could .... The multiple trait models in scalar notation are presented by equations (1, 2), while equation. (3) represents the random ...

  17. Randomized response methods

    NARCIS (Netherlands)

    van der Heijden, P.G.M.; Cruyff, Maarten; Bockenholt, U.

    2014-01-01

    In survey research it is often problematic to ask people sensitive questions because they may refuse to answer or they may provide a socially desirable answer that does not reveal their true status on the sensitive question. To solve this problem Warner (1965) proposed randomized response (RR). Here

  18. Random eigenvalue problems revisited

    Indian Academy of Sciences (India)

    The description of real-life engineering structural systems is associated with some amount of uncertainty in specifying material properties, geometric parameters, boundary conditions and applied loads. In the context of structural dynamics it is necessary to consider random eigenvalue problems in order to account for these ...

  19. absolutely regular random sequences

    Directory of Open Access Journals (Sweden)

    Michel Harel

    1996-01-01

    Full Text Available In this paper, the central limit theorems for the density estimator and for the integrated square error are proved for the case when the underlying sequence of random variables is nonstationary. Applications to Markov processes and ARMA processes are provided.

  20. A random matrix analysis

    Indian Academy of Sciences (India)

    chaos to galaxies. We demonstrate the applicability of random matrix theory for networks by pro- viding a new dimension to complex systems research. We show that in spite of huge differences ... as mentioned earlier, different types of networks can be constructed based on the nature of connections. For example,.

  1. Random eigenvalue problems revisited

    Indian Academy of Sciences (India)

    Several studies have been conducted on this topic since the mid-sixties. The. A list of .... Random eigenvalue problems revisited. 297 and various elements of Hij ,i ≤ j are statistically independent and Gaussian. The pdf of H can be expressed as, ...... Generality of this result however remains to be verified in future studies.

  2. On Randomness and Probability

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 1; Issue 2. On Randomness and Probability How to Mathematically Model Uncertain Events ... Author Affiliations. Rajeeva L Karandikar1. Statistics and Mathematics Unit, Indian Statistical Institute, 7 S J S Sansanwal Marg, New Delhi 110 016, India.

  3. Suboptimal feedback control of TCP flows in computer network using random early discard (RED mechanism

    Directory of Open Access Journals (Sweden)

    Ahmed N. U.

    2005-01-01

    Full Text Available We consider a dynamic model that simulates the interaction of TCP sources with active queue management system (AQM. We propose a modified version of an earlier dynamic model called RED. This is governed by a system of stochastic differential equations driven by a doubly stochastic point process with intensity as the control. The feedback control law proposed observes the router (queue status and controls the intensity by sending congestion signals (warnings to the sources for adjustment of their transmission rates. The (feedback control laws used are of polynomial type (including linear with adjustable coefficients. They are optimized by use of genetic algorithm (GA and random recursive search (RRS technique. The numerical results demonstrate that the proposed model and the method can improve the system performance significantly.

  4. Variability in Measures of Exhaled Breath Na, Influence of pulmonary Blood Flow and salivary Na

    Directory of Open Access Journals (Sweden)

    Courtney M. Wheatley

    2010-04-01

    Full Text Available The assessment of inflammatory markers and ions in exhaled breath condensate (EBC is being utilized more frequently in diseases such as asthma and cystic fibrosis with marked variability in EBC measures, including those of exhaled Na + . We sought to determine if variability in exhaled Na + was due to differences in pulmonary blood flow (PBF or Na + in the mouth (salivary Na + . We measured exhaled Na + three times with coinciding sampling of salivary Na + and assessment of PBF (using acetylene rebreathing in 13 healthy subjects (54% female, age = 27 ± 7 yrs., ht. = 172 ± 10 cm, wt. = 70 ± 21 kg, BMI = 22 ± 7 kg/m 2 mean ± SD. Exhaled Na + averaged 2.7 ± 1.2 mmol/l, and salivary Na + averaged 5.51 ± 4.58 mmol/l. The coefficients of variation across all three measures in all 13 subjects averaged 30% for exhaled Na + and 83% for salivary Na + , within subjects the variability across the three measures averaged 30% for exhaled Na + and 38% for salivary Na + . Across all three measures in all 13 subjects the relationship between PBF and exhaled Na + averaged 0.027 ( P = 0.87, and the relationship between salivary Na + and exhaled Na + concentrations averaged 0.59 ( P = 0.001. Also, we sought to determine the relationship between exhaled Na + and serum Na + in an addition 20 subjects. There was a moderate and significant relationship between serum Na + and exhaled Na + (r = 0.37, P = 0.04. These findings suggest there that the variability in exhaled Na + is caused, at least in part, by droplet formation from within the mouth as turbulent air passes through and that there is a flux of ions from the pulmonary blood into the airways.

  5. Istraživanje uticaja nekih parametara na osetljivost eksplozivnih materija na toplotni impuls

    OpenAIRE

    Jeremić Radun

    2002-01-01

    Ispitivana je osetljivost nekoliko vrsta eksplozivnih materija na toplotni impuls merenjem vremena zadrške u zavisnosti od temperature. Na osnovu eksperimentalnih rezultata određene su vrednosti energije aktivacije i predeksponencijalni faktori u jednačini Semjonova. Istraživan je i uticaj mase ispitivanog uzorka, granulacije i veličine kristala eksploziva na osetljivost na toplotni impuls. Pokazano je da ovi parametri imaju značajan uticaj na osetljivost eksplozivnih materija, pa je neophodn...

  6. Alzheimer random walk

    Science.gov (United States)

    Odagaki, Takashi; Kasuya, Keisuke

    2017-09-01

    Using the Monte Carlo simulation, we investigate a memory-impaired self-avoiding walk on a square lattice in which a random walker marks each of sites visited with a given probability p and makes a random walk avoiding the marked sites. Namely, p = 0 and p = 1 correspond to the simple random walk and the self-avoiding walk, respectively. When p> 0, there is a finite probability that the walker is trapped. We show that the trap time distribution can well be fitted by Stacy's Weibull distribution b(a/b){a+1}/{b}[Γ({a+1}/{b})]-1x^a\\exp(-a/bx^b)} where a and b are fitting parameters depending on p. We also find that the mean trap time diverges at p = 0 as p- α with α = 1.89. In order to produce sufficient number of long walks, we exploit the pivot algorithm and obtain the mean square displacement and its Flory exponent ν(p) as functions of p. We find that the exponent determined for 1000 step walks interpolates both limits ν(0) for the simple random walk and ν(1) for the self-avoiding walk as [ ν(p) - ν(0) ] / [ ν(1) - ν(0) ] = pβ with β = 0.388 when p ≪ 0.1 and β = 0.0822 when p ≫ 0.1. Contribution to the Topical Issue "Continuous Time Random Walk Still Trendy: Fifty-year History, Current State and Outlook", edited by Ryszard Kutner and Jaume Masoliver.

  7. Silicene for Na-ion battery applications

    KAUST Repository

    Zhu, Jiajie

    2016-08-19

    Na-ion batteries are promising candidates to replace Li-ion batteries in large scale applications because of the advantages in natural abundance and cost of Na. Silicene has potential as the anode in Li-ion batteries but so far has not received attention with respect to Na-ion batteries. In this context, freestanding silicene, a graphene-silicene-graphene heterostructure, and a graphene-silicene superlattice are investigated for possible application in Na-ion batteries, using first-principles calculations. The calculated Na capacities of 954mAh/g for freestanding silicene and 730mAh/g for the graphenesilicene superlattice (10% biaxial tensile strain) are highly competitive and potentials of >0.3 V against the Na/Na potential exceed the corresponding value of graphite. In addition, the diffusion barriers are predicted to be <0.3 eV.

  8. VPLIV VODENJA NA RAZVOJ ORGANIZACIJE

    OpenAIRE

    Rauš, Ivo

    2010-01-01

    Ključno vlogo pri razvoju človeških potencialov in sproščanju posameznikovih notranjih zmožnosti imajo njihovi neposredni vodje. Le ti naj bi skrbeli za ustvarjanje takega delovnega okolja, ki bo spodbujalo ustvarjalne dosežke, inovativnost, izvirnost idej, pripadnost in timsko sodelovanje. Vodenje zavzema prvo mesto na lestvici ključnih managerskih izzivov sedanjosti in srednjeročne prihodnosti, o čemer govorijo tudi številne zadnje raziskave ameriških in evropskih strokovnjakov za razvoj...

  9. Chiaroscuro: a luz na sombra

    OpenAIRE

    Flamínio Jallageas de Lima Cardoso

    2015-01-01

    Este ensaio objetiva refletir sobre minha série fotográfica Chiaroscuro, na qual trabalho constrastes entre luz e sombra e as consequentes representações de vazio e memória. Para tanto, elejo os teóricos da antropologia da imagem Jacques Rancière, Georges Didi-Huberman, Victor Stoichita e Hans Belting como meus interlocutores. Uma vez que um dos propósitos deste trabalho abrange observar possíveis inter-relações entre a série e alguns artistas contemporâneos, estabeleço reflexões acerca da pr...

  10. Na alvorada de um sport

    OpenAIRE

    Sartori, Carina

    2013-01-01

    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Filosofia e Ciências Humanas, Programa de Pós-graduação em História, Florianópolis, 2013 Em Florianópolis, a primeira Sociedade de Regatas organizada, meados do século XIX, contaria com a participação dos Coronéis da Marinha e da Escola de Menores e Marinheiros da Canhoneira. Na virada do século, a fundação do Clube 29 de Abril permitiria que as atividades relacionadas ao Remo fossem oferecidas a todos que se associ...

  11. A virtude na psicologia positiva

    OpenAIRE

    Cardoso, José Augusto Rento

    2014-01-01

    O presente trabalho de psicologia teórica trata-se de um estudo crítico do conceito de virtude na Psicologia Positiva. Definida como movimento por alguns e como um novo campo por outros, a Psicologia Positiva reúne sob um mesmo “guarda-chuva” diversos estudos, passados e presentes, de várias áreas da Psicologia, como a Psicologia da Personalidade, a Psicologia Social, a Psicologia do Desenvolvimento e a Psicologia Moral. No presente trabalho, a mesma é compreendida como uma perspectiva e um m...

  12. Tortura : na atividade policial investigativa

    OpenAIRE

    Giudice de Argollo, Helvécio

    2003-01-01

    Este trabalho versa sobre o fenômeno social da tortura; do seu sentido polissêmico, do seu aspecto multifacetado e dos desafios que engendra, notadamente da sua perseverança nas sociedades, a despeito do banimento pelos textos legais, tanto no plano do direito transnacional quanto na maioria dos ordenamentos jurídicos do mundo ocidental. A tortura tem uma história que se confunde com a história da própria humanidade e, nesse sentido, o seu estudo desafia um périplo histórico...

  13. The NA62 RICH detector

    Energy Technology Data Exchange (ETDEWEB)

    Lenti, Massimo, E-mail: lenti@fi.infn.i [Sezione dell' INFN di Firenze, I-50019 Sesto Fiorentino (Italy)

    2011-05-21

    The NA62 RICH must separate charged pions from muons in a 15-35 GeV/c momentum range. The detector will have a 17 m long, 4 m wide cylindrical vessel, filled with neon at an atmospheric pressure. A mosaic of 20 mirrors, with 17 m focal length will be placed at the downstream end of the vessel while 2000 single anode photomultipliers will be placed at the upstream part. Two test beams were held at CERN in 2007 and 2009 with a RICH prototype. A muon suppression factor greater than 100 was validated.

  14. New results from NA49

    CERN Document Server

    Afanasiev, S V; Bächler, J; Barna, D; Barnby, L S; Bartke, Jerzy; Barton, R A; Behler, M; Betev, L; Bialkowska, H; Billmeier, A; Blume, C; Blyth, C O; Boimska, B; Botje, M; Bracinik, J; Brady, F P; Bramm, R; Brun, R; Buncic, P; Carr, L; Cebra, D; Cerny, V; Cooper, G E; Cramer, J G; Csató, P; Dinkelaker, P; Eckardt, V; Eckhardt, F; Ferenc, D; Filip, P; Fischer, H G; Foder, Z; Foka, P Y; Freund, P; Friese, V; Gál, J; Ganz, R E; Gazdzicki, M; Georgopoulos, G; Gladysz-Dziadus, E; Harris, J W; Hegyi, S; Höhne, C; Igo, G; Jacobs, P; Jones, P G; Kadija, K; Kolesnikov, V I; Kollegger, T; Kowalski, M; Kraus, I; Kreps, M; Lasiuk, B; Van Leeuwen, M; Lévai, Peter; Malakhov, A I; Margetis, S; Markert, C; Mayes, B W; Melkumov, G L; Mischke, A; Molnár, J; Nelson, J M; Odyniec, Grazyna Janina; Oldenburg, M; Pálla, G; Panagiotou, A D; Perl, K; Petridis, A; Pikna, M; Pinsky, L; Poskanzer, A M; Prindle, D J; Pühlhofer, F; Putschke, J; Reid, J G; Renfordt, A; Retyk, W; Ritter, H G; Röhrich, D; Roland, C; Roland, G; Rybicki, A; Sammer, T; Sann, H; Schäfer, E; Schmitz, N; Seyboth, P; Siklér, F; Sitár, B; Skrzypczak, E; Snellings, R; Squier, G T A; Stock, Reinhard; Ströbele, H; Susa, T; Szentpétery, I; Sziklai, J; Toy, M; Trainor, T A; Trentalange, S; Ullrich, T S; Varga, D; Vassiliou, Maria; Veres, G I; Vesztergombi, G; Voloshin, S A; Vranic, D; Wang, F; Weerasundara, D D; Wenig, S; Wetzler, A; Whitten, C; Xu, N; Yates, T A; Koo, I K; Zaranek, J; Zimányi, J

    2002-01-01

    Recent results of the NA49 experiment are presented. These cover first results on pion and kaon production, HBT, and charge fluctuations from Pb+Pb reactions at 40 AGeV and their comparison to 158 AGeV beam energy. Furthermore a study on baryon number transfer in p+p, centrality selected p+Pb and Pb+Pb collisions at 158 AGeV and new results on the system size dependence of kaon yields, including C+C and Si+Si data, are presented. Additionally, a first result on Lambda Lambda correlations is shown. (11 refs).

  15. Treament and prevention of anemia with ferrous sulfate plus folic acid in children attending daycare centers in Goiânia, Goiás State, Brazil: a randomized controlled trial Resposta terapêutica e profilática com ferro e ácido fólico na anemia em crianças de creches públicas em Goiânia, Goiás, Brasil: ensaio clínico randomizado

    Directory of Open Access Journals (Sweden)

    Maria Claret Costa Monteiro Hadler

    2008-01-01

    Full Text Available The objective of this study was to assess the prevalence of anemia and the therapeutic and prophylactic response to ferrous sulfate and folic acid. A double-blind, randomized, controlled clinical trial was conducted with 196 children 6 to 24 months of age enrolled in municipal daycare centers in Goiânia, Goiás State, Brazil. The children were assigned to two treatment groups that received a daily dose (5 times a week of either 4.2mg/kg/day of ferrous sulfate + folic acid (50µg or 4.2mg/kg/day of ferrous sulfate + folic acid placebo. One of the prevention groups received 1.4mg/kg/day of ferrous sulfate + folic acid (50µg/day and the other 1.4mg/kg/day of ferrous sulfate + folic acid placebo. Supplementation lasted approximately three months. Baseline anemia prevalence was 56.1% (95%CI: 48.9-63.1. After treatment, anemia prevalence in the folic acid group (14% was lower than in the placebo group (34.9% (p = 0.02. After prophylaxis in the non-anemic children, the incidence of anemia did not differ between the groups, but there was an increase in hemoglobin level in the folic acid group (p = 0.003. Iron plus folic acid was effective for the treatment of anemia and improvement of hemoglobin level in non-anemic children.Avaliar a prevalência de anemia e a resposta terapêutica e profilática do sulfato ferroso e ácido fólico. Realizou-se um ensaio clínico controlado randomizado, duplo-cego, com 196 crianças de 6 a 24 meses, dos Centros Municipais de Educação Infantil de Goiânia, Goiás, Brasil. As crianças foram alocadas em dois grupos de tratamento que receberam dose diária (5x/semana com 4,2mg/kg/dia de sulfato ferroso + ácido fólico (50µg ou 4,2mg/kg/dia de sulfato ferroso + placebo de ácido fólico. Um dos grupos de prevenção recebeu 1,4 mg/kg/dia de sulfato ferroso + ácido fólico (50µg/dia e o outro 1,4mg/kg/dia de sulfato ferroso + placebo de ácido fólico. A suplementação durou cerca de três meses. A prevalência de

  16. Random vibrations theory and practice

    CERN Document Server

    Wirsching, Paul H; Ortiz, Keith

    1995-01-01

    Random Vibrations: Theory and Practice covers the theory and analysis of mechanical and structural systems undergoing random oscillations due to any number of phenomena— from engine noise, turbulent flow, and acoustic noise to wind, ocean waves, earthquakes, and rough pavement. For systems operating in such environments, a random vibration analysis is essential to the safety and reliability of the system. By far the most comprehensive text available on random vibrations, Random Vibrations: Theory and Practice is designed for readers who are new to the subject as well as those who are familiar with the fundamentals and wish to study a particular topic or use the text as an authoritative reference. It is divided into three major sections: fundamental background, random vibration development and applications to design, and random signal analysis. Introductory chapters cover topics in probability, statistics, and random processes that prepare the reader for the development of the theory of random vibrations a...

  17. Random Raman lasing

    CERN Document Server

    Hokr, Brett H; Mason, John D; Beier, Hope T; Rockwll, Benjamin A; Thomas, Robert J; Noojin, Gary D; Petrov, Georgi I; Golovan, Leonid A; Yakovlev, Vladislav V

    2013-01-01

    Propagation of light in a highly scattering medium is among the most fascinating optical effect that everyone experiences on an everyday basis and possesses a number of fundamental problems which have yet to be solved. Conventional wisdom suggests that non-linear effects do not play a significant role because the diffusive nature of scattering acts to spread the intensity, dramatically weakening these effects. We demonstrate the first experimental evidence of lasing on a Raman transition in a bulk three-dimensional random media. From a practical standpoint, Raman transitions allow for spectroscopic analysis of the chemical makeup of the sample. A random Raman laser could serve as a bright Raman source allowing for remote, chemically specific, identification of powders and aerosols. Fundamentally, the first demonstration of this new light source opens up an entire new field of study into non-linear light propagation in turbid media, with the most notable application related to non-invasive biomedical imaging.

  18. On fairness and randomness

    DEFF Research Database (Denmark)

    Jaeger, Manfred

    2009-01-01

    We investigate the relation between the behavior of non-deterministic systems under fairness constraints, and the behavior of probabilistic systems. To this end, first a framework based on computable stopping strategies is developed that provides a common foundation for describing both fair...... and probabilistic behavior. On the basis of stopping strategies it is then shown that fair behavior corresponds in a precise sense to random behavior in the sense of Martin-Löf's definition of randomness. We view probabilistic systems as concrete implementations of more abstract non-deterministic systems. Under...... this perspective the question is investigated what probabilistic properties are needed in such an implementation to guarantee (with probability one) certain required fairness properties in the behavior of the probabilistic system. Generalizing earlier concepts of ε -bounded transition probabilities, we introduce...

  19. Free random variables

    CERN Document Server

    Voiculescu, Dan; Nica, Alexandru

    1992-01-01

    This book presents the first comprehensive introduction to free probability theory, a highly noncommutative probability theory with independence based on free products instead of tensor products. Basic examples of this kind of theory are provided by convolution operators on free groups and by the asymptotic behavior of large Gaussian random matrices. The probabilistic approach to free products has led to a recent surge of new results on the von Neumann algebras of free groups. The book is ideally suited as a textbook for an advanced graduate course and could also provide material for a seminar. In addition to researchers and graduate students in mathematics, this book will be of interest to physicists and others who use random matrices.

  20. Intravaginal stimulation randomized trial.

    Science.gov (United States)

    Smith, J J

    1996-01-01

    The effectiveness of intravaginal electrical stimulation was compared to standard therapy in the treatment of genuine stress urinary incontinence and detrusor instability. A total of 57 women with urinary incontinence was evaluated with video urodynamics and voiding diaries before and after treatment. Of the women 18 with stress urinary incontinence were randomized to electrical stimulation or Kegel exercise and 38 with detrusor instability were randomized to anticholinergic therapy or electrical stimulation. Of patients using electrical stimulation in the stress urinary incontinence group 66% improved and 72% of the patients with detrusor instability treated with electrical stimulation improved. These rates were not statistically significant when compared to traditional therapy. Electrical stimulation is safe and at least as effective as properly performed Kegel and anticholinergic therapy in the treatment of stress urinary incontinence and detrusor instability.

  1. Certified randomness in quantum physics.

    Science.gov (United States)

    Acín, Antonio; Masanes, Lluis

    2016-12-07

    The concept of randomness plays an important part in many disciplines. On the one hand, the question of whether random processes exist is fundamental for our understanding of nature. On the other, randomness is a resource for cryptography, algorithms and simulations. Standard methods for generating randomness rely on assumptions about the devices that are often not valid in practice. However, quantum technologies enable new methods for generating certified randomness, based on the violation of Bell inequalities. These methods are referred to as device-independent because they do not rely on any modelling of the devices. Here we review efforts to design device-independent randomness generators and the associated challenges.

  2. Certified randomness in quantum physics

    Science.gov (United States)

    Acín, Antonio; Masanes, Lluis

    2016-12-01

    The concept of randomness plays an important part in many disciplines. On the one hand, the question of whether random processes exist is fundamental for our understanding of nature. On the other, randomness is a resource for cryptography, algorithms and simulations. Standard methods for generating randomness rely on assumptions about the devices that are often not valid in practice. However, quantum technologies enable new methods for generating certified randomness, based on the violation of Bell inequalities. These methods are referred to as device-independent because they do not rely on any modelling of the devices. Here we review efforts to design device-independent randomness generators and the associated challenges.

  3. O ATLETISMO NA PERSPECTIVA EDUCACIONAL

    Directory of Open Access Journals (Sweden)

    Leandro Araujo de Sousa

    2017-06-01

    Full Text Available A educação física escolar deve proporcionar experiências aos alunos para o seu desenvolvimento integral. As aulas muitas vezes são reduzidas ao ensino de esportes tradicionais, o que limita o repertório de movimentos dos alunos. Dessa forma o presente estudo de revisão objetiva problematizar o atletismo no ambiente escolar e propor possibilidades pedagógicas para seu ensino. Nesta pesquisa propomos tratar o ensino do atletismo na escola, caracterizando-o pelo seu repertório de movimentos que são naturais ao ser humano, como correr, saltar e lançar, o que possibilita maior praticidade em sua aplicação pedagógica, porém essas possibilidades não são consideradas no ambiente educacional. Diante dos dados encontrados, sugerimos que esse esporte seja abordado de forma multidimensional no ambiente escolar contextualizando-o à visão de algumas correntes teóricas. Nessa perspectiva do esporte educacional, o atletismo pode, assim como deve ser trabalhado nas aulas de educação física como instrumento pedagógico de ensino e auxiliar na formação do aluno de forma global.

  4. Identidades Homossexuais na Territorialidade Tradicionalista

    Directory of Open Access Journals (Sweden)

    Edipo Djavan dos Reis Göergen

    2015-12-01

    Full Text Available Este artigo apresenta o debate teórico que sustenta a pesquisa de mestrado desenvolvida pelo autor. Tendo por base suas vivências em contextos de tradicionalismo gaúcho, o autor deste trabalho tem percebido a grande quantidade de homossexuais, ou indivíduos que se auto-denominam não-heterossexuais, integrando as atividades artísticas do Movimento Tradicionalista Gaúcho, ou a territorialidade tradicionalista. Interessado em investigar tal fenômeno, o autor tem desenvolvido o projeto de pesquisa “Os Espaços Paradoxais de Relações Homoeróticas na Territorialidade Tradicionalista”, sob orientação do prof. Dr. Benhur Pinós da Costa, no Programa de Pós-Graduação em Geografia (UFSM. Para que essa pesquisa seja realizada, levam-se em conta as relações de gênero e de sexualidade que estão envolvidas no tema. Dessa forma, por ainda se tratarem de temáticas tidas como insignificantes na sociedade em geral e marginalizadas no campo científico, para que o presente trabalho fosse empreendido, buscou-se amparo teórico nas geografias feministas e queer, segmentos contemporâneos da ciência geográfica.

  5. Hydrochlorothiazide in intensive care unit-acquired hypernatremia: A randomized controlled trial.

    Science.gov (United States)

    van IJzendoorn, Marjolein M C O; Buter, Hanneke; Kingma, W Peter; Koopmans, Matty; Navis, Gerjan; Boerma, E Christiaan

    2017-04-01

    Thiazides are suggested as a treatment for intensive care unit (ICU)-acquired hypernatremia (IAH). The primary aim of the study was reducing serum sodium concentration (sNa) in patients with IAH with hydrochlorothiazide (HCT) in comparison to placebo. Secondary end points were a difference in urine sodium concentration (uNa) and duration of severe IAH. A monocentric, double-blind, placebo-controlled trial was conducted in 50 patients with IAH and urine potassium + uNa less than sNa in a spot urine sample. Patients were randomized to HCT 25 mg or placebo 1 qd for maximal 7 days. Patients on renal replacement therapy, on medication inducing diabetes insipidus, or with recent use of diuretics were excluded. IAH was defined as sNa of at least 143 mmol/L. At baseline, sNa and uNa were comparable between groups. During the study period, sNa decreased significantly with median 4 mmol/L in both groups, with no significant difference between groups (P=.32). Median uNa increased significantly in both groups (46 [16-86] mmol/L in the HCT-group; 20 [10-66]mmol/L in the placebo group), with no difference between groups (P=.34). Median duration of sNa of at least 145 mmol/L was 3 days in both groups (P=.91). HCT 25 mg 1 qd did not significantly affect sNa or uNa in patients with IAH. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

  6. NSAID Use after Bariatric Surgery: a Randomized Controlled Intervention Study.

    Science.gov (United States)

    Yska, Jan Peter; Gertsen, Sanneke; Flapper, Gerbrich; Emous, Marloes; Wilffert, Bob; van Roon, Eric N

    2016-12-01

    Use of nonsteroidal anti-inflammatory drugs (NSAIDs) should be avoided in bariatric surgery patients. If use of an NSAID is inevitable, a proton pump inhibitor (PPI) should also be used. To determine the effect of an, compared to care-as-usual, additional intervention to reduce NSAID use in patients who underwent bariatric surgery, and to determine the use of PPIs in patients who use NSAIDs after bariatric surgery. A randomized controlled intervention study in patients after bariatric surgery. Patients were randomized to an intervention or a control group. The intervention consisted of sending a letter to patients and their general practitioners on the risks of use of NSAIDs after bariatric surgery and the importance of avoiding NSAID use. The control group received care-as-usual. Dispensing data of NSAIDs and PPIs were collected from patients' pharmacies: from a period of 6 months before and from 3 until 9 months after the intervention. Two hundred forty-eight patients were included (intervention group: 124; control group: 124). The number of users of NSAIDs decreased from 22 to 18 % in the intervention group and increased from 20 to 21 % in the control group (NS). The use of a PPI with an NSAID rose from 52 to 55 % in the intervention group, and from 52 to 69 % in the control group (NS). Informing patients and their general practitioners by letter, in addition to care-as-usual, is not an effective intervention to reduce the use of NSAIDs after bariatric surgery (trial number NTR3665).

  7. Micotoxinas e Micotoxicoses na Avicultura

    Directory of Open Access Journals (Sweden)

    Santurio JM

    2000-01-01

    Full Text Available Esta revisão tem como objetivo principal mostrar, baseado em dezenas de pesquisas realizadas, os efeitos tóxicos das micotoxinas aflatoxinas, tricotecenos, zealenona e fumonisinas sobre o desempenho das aves. O descobrimento das propriedades hepatotóxicas e hepatocarcinogênicas de algumas linhagens de Aspergillus flavus e A. parasiticus em perus, na Inglaterra, no início da década de 1960, seguida pela elucidação da estrutura de seus metabólitos tóxicos, as aflatoxinas, deu novo enfoque e prioridade para a pesquisa sobre micotoxinas. Análises de aflatoxinas realizadas no Laboratório de Análises Micotoxicológicas (LAMIC da Universidade Fedaral de Santa Maria, entre os anos de 1986 e janeiro de 2000, em 15.600 amostras de alimentos destinados principalmente ao consumo animal, demonstram que no milho analisado, 41,9% das amostras estavam contaminadas por aflatoxinas. Em surtos de aflatoxicose no campo, uma das características mais marcantes é a má absorção que se manifesta como partículas de ração mal digeridas na excreta das aves. Também observa-se, em frangos e poedeiras que recebem AFL, extrema palidez das mucosas e pernas. Dietas deficientes em riboflavina ou colecalciferol (vit. D tornaram frangos sensíveis, nos índices de desenvolvimento corporal, a concentrações muito baixas de AFL. O efeito aflatoxina nos frangos é maior na fase inicial de crescimento, ou seja, quando as aves ingeriram aflatoxina nos primeiros 21 dias de vida, e quanto maior o nível de stress do lote, menor a quantidade de AFL para afetar negativamente seu desempenho, seja na produção de carne ou de ovos. As principais micotoxinas do grupo dos tricotecenos são: toxina T-2; deoxynivalenol (DON; diacetoxyscirpenol (DAS, todas produzidas através de diversas espécies de fungos do gênero Fusarium. Além dos tricotecenos, o fusarium também pode produzir zearalenona e fumonisinas. Dessas fusarium-toxinas, somente toxina T-2 gera patologias s

  8. Evaluation of FcγRIIIB-NA1/NA2 Polymorphism in Visceral Leishmaniasis.

    Science.gov (United States)

    Abasi, Mohammad; Lotfi, Pegah; Bazmani, Ahad; Matini, Mohamad; Hajilooi, Mehrdad

    2014-04-01

    Several lines of evidence demonstrating that innate and adaptive immunity play important roles in the defense against visceral leishmaniasis (VL). A polymorphism within the FcγRIIIB gene can lead to the expression of three variants of NA1, NA2, and the combined one (NA1/NA2) which alters affinity of IgG to its receptor. The main aim of this study was to evaluate the FcγRIIIB-NA1/NA2 polymorphism in the FcγRIIIB gene of VL patients in comparison to healthy controls. In this cross-sectional study, three groups; 54 seropositive patients with clinical presentation of VL (group 1), 104 seropositive patients without clinical presentation (group 2), and 104 healthy controls (group 3) were evaluated with respect to the FcγRIIIB-NA1/NA2 polymorphism using a PCR-SSP method. The titration of anti-leishmania antibodies was analyzed using an immunoflorescence technique. Our results indicated that polymorphisms within the FcγRIIIB gene (that lead to the expression of the NA1/NA2 isoforms) are significantly associated with VL. The results demonstrated that the genotype heterozygotic for FcγRIIIB-NA1/NA2 expression was significantly increased in VL patients, group 1 when compared to groups 2 and 3. Conversely, there is a decrease in homozygous NA1 and NA2 genotypes in VL patients; however, the overall frequency of NA1 and NA2 alleles appear similar across the three cohorts examined. According to our results, it is likely that the increased frequency of the FcγRIIIB-NA1/NA2 genotype is associated with impaired immune responses against VL and its subsequent clearance from the patient.

  9. Growth of binary organic NLO crystals: m.NA-p.NA and m.NA-CNA system

    Science.gov (United States)

    Singh, N. B.; Henningsen, T.; Hopkins, R. H.; Mazelsky, R.

    1993-01-01

    Experiments were carried out to grow 3.Nitroaniline (m.NA) crystals doped with 4.Nitroaniline (p.NA) and 2.chloro 4.Nitroaniline (CNA). The measured undercooling for m.NA, p.NA, and CNA were 0.21 tm K, 0.23 tm K, and 0.35 tm K respectively, where tm represents the melting temperature of the pure component. Because of the crystals' large heat of fusion and large undercooling, it was not possible to grow good quality crystals with low thermal gradients. In the conventional two-zone Bridgman furnace we had to raise the temperature of the hot zone above the decomposition temperature of CNA, p.NA, and m.NA to achieve the desired thermal gradient. To avoid decomposition, we used an unconventional Bridgman furnace. Two immiscible liquids, silicone oil and ethylene glycol, were used to build a special two-zone Bridgman furnace. A temperature gradient of 18 K/cm was achieved without exceeding the decomposition temperature of the crystal. The binary crystals, m.NA-p.NA and m.NA-CNA, were grown in centimeter size in this furnace. X-ray and optical characterization showed good optical quality.

  10. Fotografia na Imprensa: conflitos na câmara escura

    Directory of Open Access Journals (Sweden)

    José Lúcio da Silva Menezes

    2014-07-01

    Full Text Available Este artigo recupera o teor ideológico do discurso que a Revista Veja elaborou sobre a classe trabalhadora que emergiu no cenário brasileiro, no final da década de 1970. O destaque dado aos trabalhadores como temática central resgatada, deve-se aos movimentos grevistas por eles encetados, após anos de ocultamento de sua resistência sob a repressão da ditadura civil-militar (1964-1985. Com a rebeldia operária, as matérias a respeito deste grupo, na Revista,foram se tornando mais constantes e visíveis, pois já não era mais possível, para a Revista Veja, ignorar a existência da classe operária que, com a força insurgente das greves, ocupava as ruas do Brasil.

  11. Relative contributions of Na+/H+ exchange and Na+/HCO3- cotransport to ischemic Na-i(+) overload in isolated rat hearts

    NARCIS (Netherlands)

    Ten Hove, M; Nederhoff, MGJ; Van Echteld, CJA

    The Na+/H+ exchanger (NHE) and/or the Na+/HCO3- cotransporter (NBC) were blocked during ischemia in isolated rat hearts. Intracellular Na+ concentration ([Na+](i)), intracellular pH (pH(i)), and energy-related phosphates were measured by using simultaneous Na-23 and P-31 NMR spectroscopy. Hearts

  12. O Tempo e o Cuidado na velhice

    Directory of Open Access Journals (Sweden)

    Wanda Pereira Patrocinio

    2016-01-01

    Full Text Available Os temas deste Volume Temático da Revista Kairós Gerontologia versam sobre o multifacetado tema do “Cuidar” na velhice, em diferentes contextos e dentro de uma abordagem multidisciplinar. Com isso, espera-se que os textos aqui apresentados possam contribuir para o campo da pesquisa e da prática na área da Gerontologia, auxiliando profissionais e familiares na complexa tarefa de cuidar de idosos.  

  13. NaLS–ascorbic acid sys

    Indian Academy of Sciences (India)

    Unknown

    Abstract. The photogalvanic effect has been studied in three systems using photogalvanic cells and. NaLS–ascorbic acid–azur A, NaLS–ascorbic acid–azur B, NaLS–ascorbic acid–azur C systems. The pho- topotential and photocurrent generated by these systems are 770⋅0, 971⋅0, 623⋅0 mV and 160⋅0, 185⋅0,. 145⋅0 ...

  14. Effect of NaFeEDTA-fortified soy sauce on zinc absorption in children.

    Science.gov (United States)

    Li, Min; Wu, Jinghuan; Ren, Tongxiang; Wang, Rui; Li, Weidong; Piao, Jianhua; Wang, Jun; Yang, Xiaoguang

    2015-03-01

    NaFeEDTA has been applied in many foods as an iron fortificant and is used to prevent iron deficiency in Fe-depleted populations. In China, soy sauce is fortified with NaFeEDTA to control iron deficiency. However, it is unclear whether Fe-fortified soy sauce affects zinc absorption. To investigate whether NaFeEDTA-fortified soy sauce affects zinc absorption in children, sixty children were enrolled in this study and randomly assigned to three groups (10 male children and 10 female children in each group). All children received daily 3 mg of (67)Zn and 1.2 mg of dysprosium orally, while the children in the three groups were supplemented with NaFeEDTA-fortified soy sauce (6 mg Fe, NaFeEDTA group), FeSO₄-fortified soy sauce (6 mg Fe, FeSO₄ group), and no iron-fortified soy sauce (control group), respectively. Fecal samples were collected during the experimental period and analyzed for the Zn content, (67)Zn isotope ratio and dysprosium content. The Fe intake from NaFeEDTA-fortified and FeSO₄-fortified groups was significantly higher than that in the control group (P sauce does not affect Zn bioavailability in children.

  15. Random recursive trees and the elephant random walk

    Science.gov (United States)

    Kürsten, Rüdiger

    2016-03-01

    One class of random walks with infinite memory, so-called elephant random walks, are simple models describing anomalous diffusion. We present a surprising connection between these models and bond percolation on random recursive trees. We use a coupling between the two models to translate results from elephant random walks to the percolation process. We calculate, besides other quantities, exact expressions for the first and the second moment of the root cluster size and of the number of nodes in child clusters of the first generation. We further introduce another model, the skew elephant random walk, and calculate the first and second moment of this process.

  16. VPLIV GRADBENIH DEJAVNIKOV NA EKONOMIKO FOTONAPETOSTNIH SISTEMOV

    OpenAIRE

    Vrečič, Nuša

    2013-01-01

    Relavantne raziskave kažejo, da fotovoltaika postaja konkurenčna preostalim konvencionalnim virom, da bo v prihodnosti bistveno vplivala na proizvodnjo energije v Evropi ter pomembno vpliva na zamnjšanje emisij toplogrednih plinov. V teoretičnem delu so zajete tehnične zasnove in delovanje fotovoltaičnih elektrarn. Pri tehničnih zasnovah so opisani materiali in njihove lastnosti, obremenitve ter načrtovanje in montaža fotonapetostnih sistemov. V nadaljevanju spoznamo osnove fotovoltaike ...

  17. OGLAŠEVANJE NA FACEBOOKU V SLOVENIJI

    OpenAIRE

    Dobnik, Monja

    2013-01-01

    Danes so zahvaljujoč napredni mobilni tehnologiji družbena omrežja z nami na vsakem koraku. Facebook (FB) se po priljubljenosti uvršča v sam vrh družbenih omrežij in glede na to, da ga uporablja že več kot milijarda zemljanov, ponuja tudi odlične trg za oglaševanje. To so ugotovili tudi slovenski podjetniki. V diplomski nalogi je predstavljeno, kako na FB oglašujejo nekatera slovenska podjetja, s pomočjo spletnega vprašalnika pa je ugotovljeno tudi, kaj o oglasih na FB menijo njegovi uporabni...

  18. Fabrication of implanted $^{22}$Na targets

    CERN Multimedia

    2002-01-01

    A knowledge of the $^{22}$Na(p,$\\gamma$)$^{23}$ Mg reaction rate is of significant astrophysical interest. In order to complete previous studies of this reaction, radioactive $^{22}$Na targets of high purity are required. We ask for support to fabricate these targets via the implantation technique at ISOLDE GPS (off—line mode) using $^{22}$Na nuclides in an Al matrix produced in Nov. 1990 at the PSI (Zürich). The $^{22}$Na nuclides are released and ionized in a surface ionisation source, mass-analyzed at ISOLDE GPS, and implanted in a Ni-Ta backing and a C—foil in a special implantation setup.

  19. Strong Decomposition of Random Variables

    DEFF Research Database (Denmark)

    Hoffmann-Jørgensen, Jørgen; Kagan, Abram M.; Pitt, Loren D.

    2007-01-01

    A random variable X is stongly decomposable if X=Y+Z where Y=Φ(X) and Z=X-Φ(X) are independent non-degenerated random variables (called the components). It is shown that at least one of the components is singular, and we derive a necessary and sufficient condition for strong decomposability...... of a discrete random variable....

  20. Random Numbers and Quantum Computers

    Science.gov (United States)

    McCartney, Mark; Glass, David

    2002-01-01

    The topic of random numbers is investigated in such a way as to illustrate links between mathematics, physics and computer science. First, the generation of random numbers by a classical computer using the linear congruential generator and logistic map is considered. It is noted that these procedures yield only pseudo-random numbers since…

  1. Investigating the Randomness of Numbers

    Science.gov (United States)

    Pendleton, Kenn L.

    2009-01-01

    The use of random numbers is pervasive in today's world. Random numbers have practical applications in such far-flung arenas as computer simulations, cryptography, gambling, the legal system, statistical sampling, and even the war on terrorism. Evaluating the randomness of extremely large samples is a complex, intricate process. However, the…

  2. O consumo na vida digital

    Directory of Open Access Journals (Sweden)

    Iuri Yudi Furukita Baptista

    2016-02-01

    Full Text Available O modelo de consumo não possui as mesmas características sempre: suas relações, motivações, formatos, espaços, interesses e atividades são construções sociais que se modificam atreladas ao cenário econômico, político e tecnológico. O presente trabalho repassa o surgimento da sociedade do consumidor para então conjecturar sobre as propriedades distintivas do consumo na vida digital. O que se defende ao final é que o consumidor já não se restringe ao papel de consumir.

  3. Dynamic randomization and a randomization model for clinical trials data.

    Science.gov (United States)

    Kaiser, Lee D

    2012-12-20

    Randomization models are useful in supporting the validity of linear model analyses applied to data from a clinical trial that employed randomization via permuted blocks. Here, a randomization model for clinical trials data with arbitrary randomization methodology is developed, with treatment effect estimators and standard error estimators valid from a randomization perspective. A central limit theorem for the treatment effect estimator is also derived. As with permuted-blocks randomization, a typical linear model analysis provides results similar to the randomization model results when, roughly, unit effects display no pattern over time. A key requirement for the randomization inference is that the unconditional probability that any patient receives active treatment is constant across patients; when this probability condition is violated, the treatment effect estimator is biased from a randomization perspective. Most randomization methods for balanced, 1 to 1, treatment allocation satisfy this condition. However, many dynamic randomization methods for planned unbalanced treatment allocation, like 2 to 1, do not satisfy this constant probability condition, and these methods should be avoided. Copyright © 2012 John Wiley & Sons, Ltd.

  4. Surgical anatomy of the maxillary nerve in the zygomatic region Anatomia cirúrgica do nervo maxilar na região zigomática

    Directory of Open Access Journals (Sweden)

    Elizandra Paccola Moretto

    2005-06-01

    Full Text Available Anatomic knowledge on the zygomatic fossa is of primary importance to improve the regional anesthetic technique of the maxillary nerve. Few reports in the literature have addressed the trajectory of the maxillary nerve and its branches in this region; thus, this study aimed at presenting information about the trajectory of these nerves. Thirty human half-heads of both genders were fixed in 10% formalin and demineralized in 5% nitric acid, and the maxillary nerve was dissected since its origin on the pterygopalatine fossa until penetration into the inferior orbital fissure. It was observed that the maxillary nerve sends one to three posterior superior alveolar branches and tuberal descendent branches, which supply the soft tissue structures of the region. The posterior superior alveolar nerves are inferiorly oriented near the maxillary tuberosity, where they penetrate the alveolar canals with the posterior superior alveolar artery and send small nerve branches that continue in an extraosseous trajectory. This study found that nearly 2/3 of the trajectory of the maxillary nerve is located in the zygomatic region, with a short segment (1/3 in the pterygopalatine fossa.O conhecimento anátomo-cirúrgico da região zigomática é fundamental para o aprimoramento de técnicas anestésicas tronculares do nervo maxilar. A literatura pouco se refere à trajetória do nervo maxilar e seus ramos nessa região, portanto, o presente estudo tem como objetivo esclarecer o percurso desses nervos. Foram dissecadas ao microscópio cirúrgico MC900 (D.F.Vasconcelos, 30 hemicabeças humanas, de ambos os sexos, que foram previamente formolizadas a 10% e desmineralizadas em ácido nítrico a 5%. Observou-se que o nervo maxilar, desde sua origem na fossa pterigopalatina até penetrar na fissura orbital inferior, emite de um a três ramos alveolares superiores posteriores e ramos tuberais descendentes que vão para estruturas moles da região. Os nervos alveolares

  5. Odpowiedź na pytanie

    Directory of Open Access Journals (Sweden)

    Michel Foucault

    2016-12-01

    Full Text Available Prezentowany artykuł Michela Foucaulta został opublikowany w 1963 roku. Foucault rozwija w nim koncepcję archeologii wiedzy – metody analizy historycznych dyskursów, którą zaprezentuje w sześć lat później w książce o tym właśnie tytule. Artykuł powstał na kanwie pytania wybranego przez autora spośród zadanych mu przez redakcję „Esprit”, które dotyczyło możliwości pojęciowego opracowania przymusu systemu dyskursywnego przy jednoczesnym zaakcentowaniu nieciągłości w jego obrębie a tym samym możliwości twórczego działania w historii ducha. A także, czy tak sformułowana aporia zakładałaby z konieczności zgodę na przymus systemu lub afirmację siły zdolnej do przekształcenia go za pomocą zewnętrznej przemocy? Tekst jest wprawką do sformułowania dojrzałej teorii dyskursu, rodzajem autoanalizy, która pozwala Foucaultowi powiązać własną metodę historyczną z „progresywistyczną polityką” myśli i rozwiązać w ten sposób dylemat pełnej determinacji i wolnego sprawstwa obecny w rozważaniach wielu strukturalistów.

  6. Optimizing antibiotics in residents of nursing homes: protocol of a randomized trial

    Directory of Open Access Journals (Sweden)

    Simor Andrew

    2002-09-01

    Full Text Available Abstract Background Antibiotics are frequently prescribed for older adults who reside in long-term care facilities. A substantial proportion of antibiotic use in this setting is inappropriate. Antibiotics are often prescribed for asymptomatic bacteriuria, a condition for which randomized trials of antibiotic therapy indicate no benefit and in fact harm. This proposal describes a randomized trial of diagnostic and therapeutic algorithms to reduce the use of antibiotics in residents of long-term care facilities. Methods In this on-going study, 22 nursing homes have been randomized to either use of algorithms (11 nursing homes or to usual practise (11 nursing homes. The algorithms describe signs and symptoms for which it would be appropriate to send urine cultures or to prescribe antibiotics. The algorithms are introduced by inservicing nursing staff and by conducting one-on-one sessions for physicians using case-scenarios. The primary outcome of the study is courses of antibiotics per 1000 resident days. Secondary outcomes include urine cultures sent and antibiotic courses for urinary indications. Focus groups and semi-structured interviews with key informants will be used to assess the process of implementation and to identify key factors for sustainability.

  7. Random Projection Trees Revisited

    OpenAIRE

    Dhesi, Aman; Kar, Purushottam

    2010-01-01

    The Random Projection Tree structures proposed in [Freund-Dasgupta STOC08] are space partitioning data structures that automatically adapt to various notions of intrinsic dimensionality of data. We prove new results for both the RPTreeMax and the RPTreeMean data structures. Our result for RPTreeMax gives a near-optimal bound on the number of levels required by this data structure to reduce the size of its cells by a factor $s \\geq 2$. We also prove a packing lemma for this data structure. Our...

  8. Random matrix theory

    CERN Document Server

    Deift, Percy

    2009-01-01

    This book features a unified derivation of the mathematical theory of the three classical types of invariant random matrix ensembles-orthogonal, unitary, and symplectic. The authors follow the approach of Tracy and Widom, but the exposition here contains a substantial amount of additional material, in particular, facts from functional analysis and the theory of Pfaffians. The main result in the book is a proof of universality for orthogonal and symplectic ensembles corresponding to generalized Gaussian type weights following the authors' prior work. New, quantitative error estimates are derive

  9. Random Cell Identifiers Assignment

    Directory of Open Access Journals (Sweden)

    Robert Bestak

    2012-01-01

    Full Text Available Despite integration of advanced functions that enable Femto Access Points (FAPs to be deployed in a plug-and-play manner, the femtocell concept still cause several opened issues to be resolved. One of them represents an assignment of Physical Cell Identifiers (PCIs to FAPs. This paper analyses a random based assignment algorithm in LTE systems operating in diverse femtocell scenarios. The performance of the algorithm is evaluated by comparing the number of confusions for various femtocell densities, PCI ranges and knowledge of vicinity. Simulation results show that better knowledge of vicinity can significantly reduce the number of confusions events.

  10. Random Constraint Satisfaction Problems

    Directory of Open Access Journals (Sweden)

    Amin Coja-Oghlan

    2009-11-01

    Full Text Available Random instances of constraint satisfaction problems such as k-SAT provide challenging benchmarks. If there are m constraints over n variables there is typically a large range of densities r=m/n where solutions are known to exist with probability close to one due to non-constructive arguments. However, no algorithms are known to find solutions efficiently with a non-vanishing probability at even much lower densities. This fact appears to be related to a phase transition in the set of all solutions. The goal of this extended abstract is to provide a perspective on this phenomenon, and on the computational challenge that it poses.

  11. Implementation of a discontinuation letter to reduce long-term benzodiazepine use--a cluster randomized trial.

    Science.gov (United States)

    van de Steeg-van Gompel, Caroline H P A; Wensing, Michel; De Smet, Peter A G M

    2009-01-01

    Although it is recommended to restrict long-term use of benzodiazepines, and considerable attention has been paid to this, long-term use continues to be a problem. An informative discontinuation letter for patients has been shown to reduce long-term benzodiazepine use in general practice. However, little is known about its wide scale implementation in primary care. To determine the effectiveness of an intensive support programme for community pharmacies to send discontinuation letters to patients in cooperation with GPs. In a cluster randomized trial, 43 control pharmacies received a written manual and 47 experimental pharmacies received an intensive support programme. Primary outcome measures were the percentage of GPs who reviewed and returned lists of eligible patients and the percentage of long-term users who were sent a discontinuation letter within 4 months. The outcomes did not differ for the experimental versus control groups: 38% and 31% of the GPs, respectively, returned the patient lists; 14% and 10% of all long-term users in the two groups, respectively, received the discontinuation letter within 4 months. Substantially more pharmacies in the experimental group than in the control group finally managed to send discontinuation letters (70% vs. 40%). About one third of the pharmacies in the control group and two thirds of the pharmacies in the intervention group finally implemented the discontinuation letter. However, this difference was not apparent in the primary outcome measures. It seems crucial to involve GPs more effectively in implementation of the discontinuation letter.

  12. Analiza utjecaja stabilizatora na određivanje elemenata vanjske orijentacije kamere na bespilotnoj letjelici

    OpenAIRE

    Gašparović, Mateo; Gajski, Dubravko

    2016-01-01

    U radu su prikazani i interpretirani rezultati analize utjecaja stabilizatora kamere na određivanje elemenata vanjske orijentacije na bespilotnim letjelicama. Riječ je o 3-osnom stabilizatoru baziranom na elektromotorima bez četkica. Prikazan je i objašnjen koncept rada stabilizatora kamera na bespilotnim letjelicama. Za potrebe rada stabilizator je unaprijeđen upotrebom drugog inercijalnog mjernog uređaja (IMU). Provedena su dva testiranja stabilizatora upotrebom jednog i dva inercijalna mje...

  13. UTJECAJ SAMOOTKRIVANJA NA FACEBOOKU NA SMANJENJE NESIGURNOSTI, SVIĐANJE I SOCIJALNU ATRAKTIVNOST

    OpenAIRE

    Vuletić, Ana

    2016-01-01

    Cilj ovog istraživanja bio je ispitati utjecaj samootkrivanja na Facebooku na smanjenje nesigurnosti, sviđanje i socijalnu atraktivnost prilikom inicijalnog kontakta. Istraživanje je provedeno na uzorku od 196 studenata u dobi od 18 do 25 godina koji su bili raspoređeni u tri eksperimentalne situacije. Svaka situacija razlikovala se po razini samootkrivanja na Facebook profilu (niska, srednja, visoka). Sudionici su procjene vlastite nesigurnosti, sviđanja i socijalne atraktivnosti prezentiran...

  14. Quincke random walkers

    Science.gov (United States)

    Pradillo, Gerardo; Heintz, Aneesh; Vlahovska, Petia

    2017-11-01

    The spontaneous rotation of a sphere in an applied uniform DC electric field (Quincke effect) has been utilized to engineer self-propelled particles: if the sphere is initially resting on a surface, it rolls. The Quincke rollers have been widely used as a model system to study collective behavior in ``active'' suspensions. If the applied field is DC, an isolated Quincke roller follows a straight line trajectory. In this talk, we discuss the design of a Quincke roller that executes a random-walk-like behavior. We utilize AC field - upon reversal of the field direction a fluctuation in the axis of rotation (which is degenerate in the plane perpendicular to the field and parallel to the surface) introduces randomness in the direction of motion. The MSD of an isolated Quincke walker depends on frequency, amplitude, and waveform of the electric field. Experiment and theory are compared. We also investigate the collective behavior of Quincke walkers,the transport of inert particles in a bath of Quincke walkers, and the spontaneous motion of a drop containing Quincke active particle. supported by NSF Grant CBET 1437545.

  15. Lectures on random interfaces

    CERN Document Server

    Funaki, Tadahisa

    2016-01-01

    Interfaces are created to separate two distinct phases in a situation in which phase coexistence occurs. This book discusses randomly fluctuating interfaces in several different settings and from several points of view: discrete/continuum, microscopic/macroscopic, and static/dynamic theories. The following four topics in particular are dealt with in the book. Assuming that the interface is represented as a height function measured from a fixed-reference discretized hyperplane, the system is governed by the Hamiltonian of gradient of the height functions. This is a kind of effective interface model called ∇φ-interface model. The scaling limits are studied for Gaussian (or non-Gaussian) random fields with a pinning effect under a situation in which the rate functional of the corresponding large deviation principle has non-unique minimizers. Young diagrams determine decreasing interfaces, and their dynamics are introduced. The large-scale behavior of such dynamics is studied from the points of view of the hyd...

  16. Random-walk enzymes

    Science.gov (United States)

    Mak, Chi H.; Pham, Phuong; Afif, Samir A.; Goodman, Myron F.

    2015-09-01

    Enzymes that rely on random walk to search for substrate targets in a heterogeneously dispersed medium can leave behind complex spatial profiles of their catalyzed conversions. The catalytic signatures of these random-walk enzymes are the result of two coupled stochastic processes: scanning and catalysis. Here we develop analytical models to understand the conversion profiles produced by these enzymes, comparing an intrusive model, in which scanning and catalysis are tightly coupled, against a loosely coupled passive model. Diagrammatic theory and path-integral solutions of these models revealed clearly distinct predictions. Comparison to experimental data from catalyzed deaminations deposited on single-stranded DNA by the enzyme activation-induced deoxycytidine deaminase (AID) demonstrates that catalysis and diffusion are strongly intertwined, where the chemical conversions give rise to new stochastic trajectories that were absent if the substrate DNA was homogeneous. The C →U deamination profiles in both analytical predictions and experiments exhibit a strong contextual dependence, where the conversion rate of each target site is strongly contingent on the identities of other surrounding targets, with the intrusive model showing an excellent fit to the data. These methods can be applied to deduce sequence-dependent catalytic signatures of other DNA modification enzymes, with potential applications to cancer, gene regulation, and epigenetics.

  17. Capsazepine, a synthetic vanilloid that converts the Na,K-ATPase to Na-ATPase

    DEFF Research Database (Denmark)

    Mahmmoud, Yasser Ahmed

    2008-01-01

    Capsazepine (CPZ), a synthetic capsaicin analogue, inhibits ATP hydrolysis by Na,K-ATPase in the presence, but not in the absence of K+. Studies with purified membranes revealed that CPZ reduced Na+-dependent phosphorylation by interference with Na+ binding from the intracellular side of the memb...

  18. Interaction between Na+/K+-pump and Na+/Ca2+-exchanger modulates intercellular communication

    DEFF Research Database (Denmark)

    Matchkov, Vladimir; Gustafsson, Helena; Rahman, Awahan

    2007-01-01

    Ouabain, a specific inhibitor of the Na(+)/K(+)-pump, has previously been shown to interfere with intercellular communication. Here we test the hypothesis that the communication between vascular smooth muscle cells is regulated through an interaction between the Na(+)/K(+)-pump and the Na(+)/Ca(2...

  19. Regeneration of plantlets under NaCl stress from NaN3 treated ...

    African Journals Online (AJOL)

    use

    2011-11-16

    Nov 16, 2011 ... plant regeneration under NaCl stressed conditions was assessed in some sugarcane (Saccharum officinarum L.) cultivars ... cell is a useful work for the establishment of pure form of species. It can facilitate .... Sub-cultures of NaN3 treated explants on different NaCl stressed cultures a. Callus proliferation ...

  20. Solid-State Random Lasers

    CERN Document Server

    Noginov, Mikhail A

    2005-01-01

    Random lasers are the simplest sources of stimulated emission without cavity, with the feedback provided by scattering in a gain medium. First proposed in the late 60’s, random lasers have grown to a large research field. This book reviews the history and the state of the art of random lasers, provides an outline of the basic models describing their behavior, and describes the recent advances in the field. The major focus of the book is on solid-state random lasers. However, it also briefly describes random lasers based on liquid dyes with scatterers. The chapters of the book are almost independent of each other. So, the scientists or engineers interested in any particular aspect of random lasers can read directly the relevant section. Researchers entering the field of random lasers will find in the book an overview of the field of study. Scientists working in the field can use the book as a reference source.

  1. Efficacy of Souvenaid in mild Alzheimer's disease: results from a randomized, controlled trial

    NARCIS (Netherlands)

    Scheltens, P.; Twisk, J.W.; Blesa, R.; Scarpini, E.; von Arnim, C.A.F.; Bongers, A.; Harrison, J.; Swinkels, S.H.N.; Stam, C.J.; de Waal, H.; Wurtman, R.J.; Wieggers, R.L.; Vellas, B.; Kamphuis, P.J.G.H.

    2012-01-01

    Souvenaid aims to improve synapse formation and function. An earlier study in patients with Alzheimer's disease (AD) showed that Souvenaid increased memory performance after 12 weeks in drug-naïve patients with mild AD. The Souvenir II study was a 24-week, randomized, controlled, double-blind,

  2. Effect of dexamethasone on skeletal muscle Na+,K+ pump subunit specific expression and K+ homeostasis during exercise in humans

    DEFF Research Database (Denmark)

    Nordsborg, Nikolai; Ovesen, Jakob; Thomassen, Martin

    2008-01-01

    The effect of dexamethasone on Na(+),K(+) pump subunit expression and muscle exchange of K(+) during exercise in humans was investigated. Nine healthy male subjects completed a randomized double blind placebo controlled protocol, with ingestion of dexamethasone (Dex: 2 x 2 mg per day) or placebo...

  3. Structure of Liquid Na-K Alloys

    NARCIS (Netherlands)

    Alblas, B.P.; Lugt, W. van der; Valk, H.J.L. van der; Hosson, J.Th.M. De; Dijk, C. van

    1980-01-01

    X-ray and neutron diffraction data are presented for a number of liquid Na-K alloys covering the whole composition range. Additionally, for the composition 50 at.% Na - 50 at.% K, a computer experiment in molecular dynamics has been carried out. An attempt is made to analyze the results in terms of

  4. Razvitak naselja na kvarnerskim otocima - primjer Dobrinja

    Directory of Open Access Journals (Sweden)

    Marijan Bradanović

    2012-12-01

    Full Text Available Na dosad slabo poznatom i sa stajališta povijesti umjetnosti još posve neobrađenom primjeru Dobrinja na otoku Krku, raspravlja se o razvitku naselja na kvarnerskim otocima. Uz isticanje štetnosti dosad prevladavajućih uopćavanja, karakteristični položaj i razvitak Dobrinja tumače se u širem, komparativnom kontekstu. Analiziraju se prostiranje i obilježja pojedinih dijelova ovog naselja, a naglasak je na vremenu kasnog srednjeg i ranijeg novog vijeka. Tada je najuži dio povijesnog središta Dobrinja poprimio čvrstu, na tlorisnoj osnovi i danas, usprkos opsežnim pregradnjama i arhitektonskim preinakama, jasno uočljivu, urbanu fizionomiju.

  5. Regulation of Na+ fluxes in plants

    Directory of Open Access Journals (Sweden)

    Frans eMaathuis

    2014-09-01

    Full Text Available When exposed to salt, every plant takes up Na+ from the environment. Once in the symplast, Na+ is distributed within cells and between different tissues and organs. There it can help to lower the cellular water potential but also exert potentially toxic effects. Control of Na+ fluxes is therefore crucial and indeed, research shows that the divergence between salt tolerant and salt sensitive plants is not due to a variation in transporter types but rather originates in the control of uptake and internal Na+ fluxes. A number of regulatory mechanisms has been identified based on signalling of Ca2+, cyclic nucleotides, reactive oxygen species, hormones, or on transcriptional and post translational changes of gene and protein expression. This review will give an overview of intra- and intercellular movement of Na+ in plants and will summarise our current ideas of how these fluxes are controlled and regulated in the early stages of salt stress.

  6. Bullying na Escola: um sofrimento

    Directory of Open Access Journals (Sweden)

    Marlene Silva Sardinha Gurpilhares

    2014-07-01

    Full Text Available O bullying é uma forma de violência presente nas escolas e o termo é utilizado para caracterizar todas as formas de agressões repetitivas psicológicas e físicas, direta ou indiretamente. Esta violência causa sofrimentos, intimidação e medo, sempre numa relação de poder entre pares. Esta pesquisa trata de um estudo do bullying escolar: o que é, como surgiu, como identificá-lo e sua caracterização, conseqüências, causas, o papel da escola, de professores e pais e uma proposta prática que pode ser adotada para sua prevenção e contenção. O objetivo é organizar materiais para leitura dos atores educacionais para uma possível reflexão, através de pesquisas bibliográficas. Esta violência é grave e deveria ser tratada como saúde pública, devido às conseqüências que traz, como queda na aprendizagem, na autoestima e em casos mais graves, até o suicido e outras tragédias. A escola necessita atentar para esse tipo de violência, revendo suas ações em todos os momentos, tendo um olhar integral e diferenciado em relação aos alunos. É fundamental que o bullying não seja tratado como brincadeira de criança e para ser identificado e combatido é necessária uma ação entre a família e todos da escola, que pode ser desenvolvida através de projetos que ajudem a apontar caminhos para a solução do problema. Tais ações devem ser pautadas por constantes debates e reflexões, nas quais o aluno se torne o protagonista. Não existem fórmulas prontas, pois a intervenção deve ser feita através da realidade de cada escola.

  7. Clues to NaCN formation ⋆

    Science.gov (United States)

    Quintana-Lacaci, G.; Cernicharo, J.; Velilla Prieto, L.; Agúndez, M.; Castro-Carrizo, A.; Fonfría, J.P.; Massalkhi, S.; Pardo, J.R.

    2017-01-01

    Context ALMA is providing us essential information on where certain molecules form. Observing where these molecules emission arises from, the physical conditions of the gas, and how this relates with the presence of other species allows us to understand the formation of many species, and to significantly improve our knowledge of the chemistry that occurs in the space. Aims We studied the molecular distribution of NaCN around IRC +10216, a molecule detected previously, but whose origin is not clear. High angular resolution maps allow us to model the abundance distribution of this molecule and check suggested formation paths. Methods We modeled the emission of NaCN assuming local thermal equilibrium (LTE) conditions. These profiles were fitted to azimuthal averaged intensity profiles to obtain an abundance distribution of NaCN. Results We found that the presence of NaCN seems compatible with the presence of CN, probably as a result of the photodissociation of HCN, in the inner layers of the ejecta of IRC +10216. However, similar as for CH3CN, current photochemical models fail to reproduce this CN reservoir. We also found that the abundance peak of NaCN appears at a radius of 3 × 1015cm, approximately where the abundance of NaCl, suggested to be the parent species, starts to decay. However, the abundance ratio shows that the NaCl abundance is lower than that obtained for NaCN. We expect that the LTE assumption might result in NaCN abundances higher than the real ones. Updated photochemical models, collisional rates, and reaction rates are essential to determine the possible paths of the NaCN formation.

  8. Načrtovanje prodaje za potrebe uvajanja pametnega avtomata za izdajo artiklov na slovenski trg

    OpenAIRE

    Grdiša, Miha

    2016-01-01

    Diplomsko delo z naslovom Načrtovanje prodaje za potrebe uvajanja pametnega avtomata za izdajo artiklov na slovenski trg je razdeljeno na dva dela, teoretični in praktični del. V prvem delu smo predstavili teoretična spoznanja oziroma izhodišča domačih in tujih avtorjev, ki govorijo o uspešnosti in načrtovanju prodaje, o vlogi prodaje nasploh in o tem, kakšno vlogo ima pri tem management prodaje. V drugem delu naloge smo predstavili podjetje Haberkorn, GMBH, ki deluje v Avstriji, in slo...

  9. Gossip in Random Networks

    Science.gov (United States)

    Malarz, K.; Szvetelszky, Z.; Szekf, B.; Kulakowski, K.

    2006-11-01

    We consider the average probability X of being informed on a gossip in a given social network. The network is modeled within the random graph theory of Erd{õ}s and Rényi. In this theory, a network is characterized by two parameters: the size N and the link probability p. Our experimental data suggest three levels of social inclusion of friendship. The critical value pc, for which half of agents are informed, scales with the system size as N-gamma with gamma approx 0.68. Computer simulations show that the probability X varies with p as a sigmoidal curve. Influence of the correlations between neighbors is also evaluated: with increasing clustering coefficient C, X decreases.

  10. Investments in random environments

    Science.gov (United States)

    Navarro-Barrientos, Jesús Emeterio; Cantero-Álvarez, Rubén; Matias Rodrigues, João F.; Schweitzer, Frank

    2008-03-01

    We present analytical investigations of a multiplicative stochastic process that models a simple investor dynamics in a random environment. The dynamics of the investor's budget, x(t) , depends on the stochasticity of the return on investment, r(t) , for which different model assumptions are discussed. The fat-tail distribution of the budget is investigated and compared with theoretical predictions. We are mainly interested in the most probable value xmp of the budget that reaches a constant value over time. Based on an analytical investigation of the dynamics, we are able to predict xmpstat . We find a scaling law that relates the most probable value to the characteristic parameters describing the stochastic process. Our analytical results are confirmed by stochastic computer simulations that show a very good agreement with the predictions.

  11. Tailored Random Graph Ensembles

    Science.gov (United States)

    Roberts, E. S.; Annibale, A.; Coolen, A. C. C.

    2013-02-01

    Tailored graph ensembles are a developing bridge between biological networks and statistical mechanics. The aim is to use this concept to generate a suite of rigorous tools that can be used to quantify and compare the topology of cellular signalling networks, such as protein-protein interaction networks and gene regulation networks. We calculate exact and explicit formulae for the leading orders in the system size of the Shannon entropies of random graph ensembles constrained with degree distribution and degree-degree correlation. We also construct an ergodic detailed balance Markov chain with non-trivial acceptance probabilities which converges to a strictly uniform measure and is based on edge swaps that conserve all degrees. The acceptance probabilities can be generalized to define Markov chains that target any alternative desired measure on the space of directed or undirected graphs, in order to generate graphs with more sophisticated topological features.

  12. The random projection method

    CERN Document Server

    Vempala, Santosh S

    2005-01-01

    Random projection is a simple geometric technique for reducing the dimensionality of a set of points in Euclidean space while preserving pairwise distances approximately. The technique plays a key role in several breakthrough developments in the field of algorithms. In other cases, it provides elegant alternative proofs. The book begins with an elementary description of the technique and its basic properties. Then it develops the method in the context of applications, which are divided into three groups. The first group consists of combinatorial optimization problems such as maxcut, graph coloring, minimum multicut, graph bandwidth and VLSI layout. Presented in this context is the theory of Euclidean embeddings of graphs. The next group is machine learning problems, specifically, learning intersections of halfspaces and learning large margin hypotheses. The projection method is further refined for the latter application. The last set consists of problems inspired by information retrieval, namely, nearest neig...

  13. Kuingiliana kwa Lugha ya Kiswahili na Kiingereza: Uswahilishaji wa ...

    African Journals Online (AJOL)

    Historia ya kukua na kuenea kwa lugha ya Kiswahili inaonyesha kuwa, lugha ya Kiswahili imeingilina na lugha nyingi. Kwanza kabisa Kiswahili kiliingiliana na lugha ya Kiarabu, katika karne ya 12 wakati Waarabu walipoingia nchini kwa madhumuni ya kuendesha biashara.Baadae ikaingiliana na lugha ya Kijerumani na ...

  14. Barroco: A tempestade na Biblioteca

    Directory of Open Access Journals (Sweden)

    Diego Cervelin

    2008-10-01

    Full Text Available http://dx.doi.org/10.5007/1984-784x.2008v8n12p167 Desde que Heinrich Wölfflin, nos últimos vinte anos do século XIX, se interessou por trazer à tona as formas arquitetônicas do século XVII conferindo-lhes caráter autônomo de estilo histórico determinável, não é nenhuma novidade que os estudos sobre o barroco pudessem polarizar – quase sempre em um tom colérico – os pesquisadores da arte e da cultura. Em terras do Brasil, não chega a ser de todo descabido recordar a severíssima crítica operada por Sérgio Buarque de Holanda em Raízes do Brasil. O livro, que pretende detectar a avalanche de equívocos que teria povoado o passado nacional com as vistas voltadas para a concretização de um projeto de emancipação e progresso na linha da história brasileira, apresenta em seu quarto capítulo uma impugnação explícita ao passado colonial.

  15. Barroco: A tempestade na Biblioteca

    Directory of Open Access Journals (Sweden)

    Diego Cervelin

    2008-12-01

    Full Text Available Desde que Heinrich Wölfflin, nos últimos vinte anos do século XIX, se interessou por trazer à tona as formas arquitetônicas do século XVII conferindo-lhes caráter autônomo de estilo histórico determinável, não é nenhuma novidade que os estudos sobre o barroco pudessem polarizar – quase sempre em um tom colérico – os pesquisadores da arte e da cultura. Em terras do Brasil, não chega a ser de todo descabido recordar a severíssima crítica operada por Sérgio Buarque de Holanda em Raízes do Brasil. O livro, que pretende detectar a avalanche de equívocos que teria povoado o passado nacional com as vistas voltadas para a concretização de um projeto de emancipação e progresso na linha da história brasileira, apresenta em seu quarto capítulo uma impugnação explícita ao passado colonial.

  16. Terapia de linguagem na afasia

    Directory of Open Access Journals (Sweden)

    Mauro Spinelli

    1977-12-01

    Full Text Available A terapia da linguagem na afasia foi estudada em 15 pacientes, 8 do sexo masculino e 7 do sexo feminino; a idade variou de menos de 10 anos a mais de 50 anos; em 11 casos a afasia era sequela de acidente vascular cerebral e, em 4, de traumatismo crânio-encefálico. Quanto ao tipo de afasia, 5 pacientes apresentavam déficits predominantemente de expressão e 10 apresentavam déficits receptivos e expressivos em graus equiparáveis. Em 6 casos a terapia foi iniciada dentro dos 3 primeiros meses de instalação do quadro; nos restantes foi iniciada mais tardiamente. Dos 15 pacientes, 11 apresentaram evolução satisfatória, a qual não depndeu do grau de afasia, do tipo de afasia, da idade do paciente, do tipo de patologia e do intervalo entre a instalação do quadro afásico e o início da terapia. A terapia da linguagem no paciente afásico é efetiva, o prognóstico não pode ser feito a priori. Somente a evolução do caso com sua retestagem criteriosa poderá dar dados realmente úteis para se falar em evolução.

  17. Random discrete Schroedinger operators from random matrix theory

    Energy Technology Data Exchange (ETDEWEB)

    Breuer, Jonathan [Institute of Mathematics, Hebrew University of Jerusalem, Jerusalem 91904 (Israel); Forrester, Peter J [Department of Mathematics and Statistics, University of Melbourne, Parkville, Vic 3010 (Australia); Smilansky, Uzy [Department of Physics of Complex Systems, Weizmann Institute, Rehovot 76100 (Israel)

    2007-02-02

    We investigate random, discrete Schroedinger operators which arise naturally in the theory of random matrices, and depend parametrically on Dyson's Coulomb gas inverse temperature {beta}. They are similar to the class of 'critical' random Schroedinger operators with random potentials which diminish as vertical bar x vertical bar{sup -1/2}. We show that as a function of {beta} they undergo a transition from a regime of (power-law) localized eigenstates with a pure point spectrum for {beta} < 2 to a regime of extended states with a singular continuous spectrum for {beta} {>=} 2. (fast track communication)

  18. Extracellular Na+ levels regulate formation and activity of the NaX/alpha1-Na+/K+-ATPase complex in neuronal cells.

    Directory of Open Access Journals (Sweden)

    Emmanuelle eBerret

    2014-12-01

    Full Text Available MnPO neurons play a critical role in hydromineral homeostasis regulation by acting as sensors of extracellular sodium concentration ([Na+]out. The mechanism underlying Na+-sensing involves Na+-flow through the NaX channel, directly regulated by the Na+/K+-ATPase α1-isoform which controls Na+-influx by modulating channel permeability. Together, these two partners form a complex involved in the regulation of intracellular sodium ([Na+]in. Here we aim to determine whether environmental changes in Na+ could actively modulate the NaX/Na+/K+-ATPase complex activity.We investigated the complex activity using patch-clamp recordings from rat MnPO neurons and Neuro2a cells. When the rats were fed with a high-salt-diet, or the [Na+] in the culture medium was increased, the activity of the complex was up-regulated. In contrast, drop in environmental [Na+] decreased the activity of the complex. Interestingly under hypernatremic condition, the colocalization rate and protein level of both partners were up-regulated. Under hyponatremic condition, only NaX protein expression was increased and the level of NaX/Na+/K+-ATPase remained unaltered. This unbalance between NaX and Na+/K+-ATPase pump proportion would induce a bigger portion of Na+/K+-ATPase-control-free NaX channel. Thus we suggest that hypernatremic environment increases NaX/Na+/K+-ATPase α1-isoform activity by increasing the number of both partners and their colocalization rate, whereas hyponatremic environment down-regulates complex activity via a decrease in the relative number of NaX channels controlled by the pump.

  19. Modeling neutron events in MoNA-LISA using MCNPX

    Science.gov (United States)

    Elliston, Margaret; Peters, Alexander; Stryker, Kristen; Stephenson, Sharon; MoNA Collaboration

    2011-10-01

    The MoNA-LISA collaboration uses time-of-flight techniques and charged particle detectors to determine the structure of exotic nuclei such as 24 O and 12 Be . To determine the decay energy in particular, a neutron that hits the Modular Neutron Array and the Large multi-Institutional Scintillator Array has its energy, position and angle of incidence recorded if and only if the charged particle detector system detects an appropriate charged-particle fragment. However, the analysis uses only the first neutron to hit the detector array even in the case of 2n events, since the data acquisition system cannot distinguish between simultaneous but random 2n events and events due to 2n reactions. We are using MCNPX to model the reaction channels possible in the MoNA-LISA detector system in an effort to better improve the resolution on decay energy spectra for events with multiple neutrons. This work was supported in part by US National Science Foundation Award 0922335.

  20. When are cellular automata random?

    Science.gov (United States)

    Coe, J. B.; Ahnert, S. E.; Fink, T. M. A.

    2008-12-01

    A random cellular automaton is one in which a cell's behaviour is independent of its previous states. We derive analytical conditions which must be satisfied by random cellular automata and find deterministic and probabilistic cellular automata that satisfy these conditions. Many random cellular automata are seen to have a flow as they are updated through time. We define a correlation current that describes this flow and develop an analytical expression for its size. We compare results from this analytical expression with those from simulation. The randomness in a cell comes from randomness in adjacent cells or from the stochastic nature of update rules. We give an expression for how much randomness comes from each of these two sources.

  1. Methods and analysis of realizing randomized grouping.

    Science.gov (United States)

    Hu, Liang-Ping; Bao, Xiao-Lei; Wang, Qi

    2011-07-01

    Randomization is one of the four basic principles of research design. The meaning of randomization includes two aspects: one is to randomly select samples from the population, which is known as random sampling; the other is to randomly group all the samples, which is called randomized grouping. Randomized grouping can be subdivided into three categories: completely, stratified and dynamically randomized grouping. This article mainly introduces the steps of complete randomization, the definition of dynamic randomization and the realization of random sampling and grouping by SAS software.

  2. [Controlled randomized clinical trials].

    Science.gov (United States)

    Jaillon, Patrice

    2007-01-01

    It is generally agreed that the first comparative clinical trial in history was done by James Lind in 1747, in the treatment of scurvy. The general bases of modern experimental medicine were published by Claude Bernard in 1865. However, it is the development of new drugs and the evolution of methodological concepts that led to the first randomized controlled clinical trial, in 1948, which showed that the effects of streptomycin on pulmonary tuberculosis were significantly different from those of a placebo. Today, "evidence-based" medicine aims to rationalize the medical decision-making process by taking into account, first and foremost, the results of controlled randomized clinical trials, which provide the highest level of evidence. In the second half of the 20th century it became clear that different kinds of clinical trials might not provide the same level of evidence. Practitioners' intimate convictions must be challenged by the results of controlled clinical trials. Take the CAST trial for example, which, in 1989, tested antiarrhythmic drugs versus placebo in patients with myocardial infarction. It was well known that ventricular arrhythmias were a factor of poor prognosis in coronary heart disease, and it was therefore considered self-evident that drug suppression of these ventricular arrhythmias would reduce the mortality rate. In the event, the CAST trial showed the exact opposite, with an almost 3-fold increase in total mortality among patients with coronary heart disease who were treated with antiarrhythmic drugs. These results had a profound impact on the use of antiarrythmic drugs, which became contraindicated after myocardial infarction. A clinical trial has to fulfill certain methodological standards to be accepted as evidence-based medicine. First, a working hypothesis has to be formulated, and then the primary outcome measure must be chosen before beginning the study. An appropriate major endpoint for efficacy must be selected, in keeping with the

  3. Fractional random walk lattice dynamics

    Science.gov (United States)

    Michelitsch, T. M.; Collet, B. A.; Riascos, A. P.; Nowakowski, A. F.; Nicolleau, F. C. G. A.

    2017-02-01

    We analyze time-discrete and time-continuous ‘fractional’ random walks on undirected regular networks with special focus on cubic periodic lattices in n  =  1, 2, 3,.. dimensions. The fractional random walk dynamics is governed by a master equation involving fractional powers of Laplacian matrices {{L}\\fracα{2}}} where α =2 recovers the normal walk. First we demonstrate that the interval 0<α ≤slant 2 is admissible for the fractional random walk. We derive analytical expressions for the transition matrix of the fractional random walk and closely related the average return probabilities. We further obtain the fundamental matrix {{Z}(α )} , and the mean relaxation time (Kemeny constant) for the fractional random walk. The representation for the fundamental matrix {{Z}(α )} relates fractional random walks with normal random walks. We show that the matrix elements of the transition matrix of the fractional random walk exihibit for large cubic n-dimensional lattices a power law decay of an n-dimensional infinite space Riesz fractional derivative type indicating emergence of Lévy flights. As a further footprint of Lévy flights in the n-dimensional space, the transition matrix and return probabilities of the fractional random walk are dominated for large times t by slowly relaxing long-wave modes leading to a characteristic {{t}-\\frac{n{α}} -decay. It can be concluded that, due to long range moves of fractional random walk, a small world property is emerging increasing the efficiency to explore the lattice when instead of a normal random walk a fractional random walk is chosen.

  4. Octonions in random matrix theory

    OpenAIRE

    Forrester, Peter J.

    2016-01-01

    The octonions are one of the four normed division algebras, together with the real, complex and quaternion number systems. The latter three hold a primary place in random matrix theory, where in applications to quantum physics they are determined as the entries of ensembles of Hermitian random by symmetry considerations. Only for $N=2$ is there an existing analytic theory of Hermitian random matrices with octonion entries. We use a Jordan algebra viewpoint to provide an analytic theory for $N...

  5. Random Numbers from Astronomical Imaging

    OpenAIRE

    Pimbblet, Kevin A.; Bulmer, Michael

    2004-01-01

    This article describes a method to turn astronomical imaging into a random number generator by using the positions of incident cosmic rays and hot pixels to generate bit streams. We subject the resultant bit streams to a battery of standard benchmark statistical tests for randomness and show that these bit streams are statistically the same as a perfect random bit stream. Strategies for improving and building upon this method are outlined.

  6. Pretpostavke za valorizaciju zapisa na elektronskim medijima

    OpenAIRE

    Eržišnik, Davorin

    1999-01-01

    U napisu se raspravlja o razlozima za valorizaciju zapisa na elektronskim medijima. Oni su ujedno i pretpostavke za tu valorizaciju, jer da bi ona uoće provodila, moraju postojati i razlozi. Istraživanje se bazira na usporedbi izmedju tih zapisa s jedne strane te klasičnih dokumenata i mikrofilmskih zapisa, s druge. Zaključuje se da u odnosu na tu drugu stranu, elektronski zapisi moraju imati i neke dodatne prednosti i kvalitete. U protivnom, ni ta valorizacija ne bi imala smisla.

  7. Nalaz tombusvirusa na vrsti Erigeron canadensis L.

    OpenAIRE

    Jeknić, Zoran; Erić, Živojin; Grbelja, Julijana

    1988-01-01

    Iz listova zaraženih primjeraka korovne biljke Erigeron canadensis L. koji su rasli na nekoliko lokaliteta u Sarajevu izoliran je virus iz skupine tombusvirusi. Identifikacija virusa izvršena je na osnovi reakcije pokusnih biljaka, analize ultratankih presjeka kroz zaraženo tkivo, morfologije i veličine virusnih čestica, te na osnovi seroloških reakcija metodom dvostruke imunodifuzije u agarskom gelu i čvrsto fazne imunoelektronske mikroskopije (SPIEM). U serološkim pokusima upotrijebljen je ...

  8. Racismo e Movimentos Instituintes na Escola

    OpenAIRE

    Eugenia da Luz Silva Foster

    2004-01-01

    Apesar da eloqüência dos discursos proclamados tanto na sociedade, como na escola, afirmando a democracia, a luta contra as desigualdades e o respeito às diferenças, somos confrontados com uma realidade de reprodução do racismo, cotidianamente. Constatando essa realidade, entendemos que o racismo se alimenta de múltiplas dimensões. Dentre tantas, ressaltamos nesta tese as mais sutis, que se alojam nos afetos, nas emoções, no imaginário político, cultural constituindo e expressando-se na...

  9. Importance of randomness in biological networks: A random matrix ...

    Indian Academy of Sciences (India)

    2015-01-29

    Jan 29, 2015 ... We show that in spite of huge differences these interaction networks, representing real-world systems, posses from random matrix models, the spectral properties of the underlying matrices of these networks follow random matrix theory bringing them into the same universality class. We further demonstrate ...

  10. NaCl as a physiological modulator of proline metabolism and antioxidant potential in Phyllanthus amarus.

    Science.gov (United States)

    Jaleel, Cheruth Abdul; Manivannan, Paramasivam; Lakshmanan, Ganapathy Murugan Alagu; Sridharan, Ramalingam; Panneerselvam, Rajaram

    2007-11-01

    Some medicinal plants need to be cultivated commercially in order to meet the ever-increasing demand for medicinal plants for the indigenous systems of medicine as well as for the pharmaceutical industry; in this regard, it seems significant to test the important medicinal plants for their salt-tolerance capacity, with a view to exploiting the saline lands for medicinal plant cultivation. Phyllanthus amarus plants were grown in the presence of NaCl in order to study the effect of NaCl (80 mM NaCl) in the induction of oxidative stress in terms of lipid peroxidation (TBARS content), H2O2 content, osmolyte concentration, proline(PRO)-metabolizing enzymes, and antioxidant enzyme activities. Groundwater was used for irrigation of control plants. Plants were uprooted randomly on 90 days after sowing (DAS). NaCl-stressed plants showed increased TBARS, H2O2, glycine betaine (GB), and PRO contents, whereas NaCl uptake decreased proline oxidase (PROX) activity and increased gamma-glutamyl kinase (gamma-GK) activity when compared to control. The antioxidant enzymes superoxide dismutase (SOD), peroxidase (POX) and catalase (CAT) were increased under salinity.

  11. Pseudo-random number generator based on asymptotic deterministic randomness

    Energy Technology Data Exchange (ETDEWEB)

    Wang Kai [Department of Radio Engineering, Southeast University, Nanjing (China)], E-mail: kaiwang@seu.edu.cn; Pei Wenjiang; Xia Haishan [Department of Radio Engineering, Southeast University, Nanjing (China); Cheung Yiuming [Department of Computer Science, Hong Kong Baptist University, Hong Kong (China)

    2008-06-09

    A novel approach to generate the pseudorandom-bit sequence from the asymptotic deterministic randomness system is proposed in this Letter. We study the characteristic of multi-value correspondence of the asymptotic deterministic randomness constructed by the piecewise linear map and the noninvertible nonlinearity transform, and then give the discretized systems in the finite digitized state space. The statistic characteristics of the asymptotic deterministic randomness are investigated numerically, such as stationary probability density function and random-like behavior. Furthermore, we analyze the dynamics of the symbolic sequence. Both theoretical and experimental results show that the symbolic sequence of the asymptotic deterministic randomness possesses very good cryptographic properties, which improve the security of chaos based PRBGs and increase the resistance against entropy attacks and symbolic dynamics attacks.

  12. Hypotonic versus isotonic maintenance fluids in critically ill pediatric patients: a randomized controlled trial.

    Science.gov (United States)

    Jorro Barón, Facundo A; Meregalli, Claudia N; Rombolá, Valeria A; Bolasell, Cecilia; Pigliapoco, Vilma E; Bartoletti, Silvia E; Debaisi, Gustavo E

    2013-01-01

    Hypotonic fluids have been associated with the development of iatrogenic hyponatremia. To assess variations in serum sodium (sNa) following the intravenous administration of isotonic maintenance fluids (0.9% NaCl/5% dextrose) compared to hypotonic maintenance fluids (0.45% NaCl/5% dextrose). Randomized, controlled, double-blind clinical trial. Pediatric patients with an expected length of stay in the intensive care unit of more than 24 hours were enrolled, with normal serum Na, and IV fluids >80% of total maintenance fluids. Serum Na level was measured before administering maintenance fluids and when reducing the administration to hypotonic (n= 32) or isotonic (n= 31) maintenance fluids. Baseline characteristics were similar in both groups. There were no differences in terms of volume of fluid administered (hypotonic group: 865 ± 853 mL; isotonic group: 778 ± 649 mL; p= 0.654) or infusion duration (hypotonic group: 24 ± 10.8 hours; isotonic group: 27.6 ± 12.8 hours; p= 0.231). A difference was found in the serum Na following the administration of maintenance fluids (hypotonic group: 137.8 ± 4.3 mmol/L; isotonic group: 140.0 ± 4.1 mmol/L, p= 0.04). None of these two maintenance fluids increased the risk of hyponatremia (Na 145 mmol/L). Neither hypotonic nor isotonic maintenance fluids increased the risk of developing iatrogenic hyponatremia with the 24 hour infusion.

  13. Ionic dependence of active Na-K transport: clamping of cellular Na/sup +/ with monensin

    Energy Technology Data Exchange (ETDEWEB)

    Haber, R.S.; Pressley, T.A.; Loeb, J.N.; Ismail-Beigi, F.

    1987-07-01

    The Na/sup +/ ionophore monensin was used to study the Na/sup +/- and K/sup +/-dependence of ouabain-inhibitable /sup 86/Rb/sup +/ uptake in ARL 15 cells, a rat liver cell line. Graded concentrations of monensin rapidly induced incremental elevations of cellular Na/sup +/ that were stable for up to 2 h. In experiments in which cellular Na/sup +/ was thus clamped at various levels, the activation curve for ouabain-inhibitable /sup 86/Rb/sup +/ uptake as a function of intracellular Na/sup +/ was found to be steepest near basal Na/sup +/ levels (Hill coefficient /congruent/ 2.4), indicating that these cells can respond to relatively large changes in passive Na/sup +/ entry by increasing the rate of Na-K pump function with only minimal increases in cellular Na/sup +/. Exposure of cells to monensin also permitted examination of the extracellular-K/sup +/ dependence of ouabain inhibitable /sup 86/Rb/sup +/ uptake in presence of saturating intracellular Na/sup +/ and yielded a Hill coefficient of approx. 1.5. The rate of ATP hydrolysis calculated from measurements of the maximal rate of ouabain-inhibitable /sup 86/Rb/sup +/ uptake in intact cells was similar to the enzymatic V/sub max/ of the Na/sup +/-K/sup +/-ATPase in cell lysates, suggesting that the Na/sup +/-K/sup +/-ATPase activity in these broken-cell preparations closely reflects the functional transport capacity of the Na-K pump.

  14. Asymmetric evolving random networks

    Science.gov (United States)

    Coulomb, S.; Bauer, M.

    2003-10-01

    We generalize the Poissonian evolving random graph model of M. Bauer and D. Bernard (2003), to deal with arbitrary degree distributions. The motivation comes from biological networks, which are well-known to exhibit non Poissonian degree distributions. A node is added at each time step and is connected to the rest of the graph by oriented edges emerging from older nodes. This leads to a statistical asymmetry between incoming and outgoing edges. The law for the number of new edges at each time step is fixed but arbitrary. Thermodynamical behavior is expected when this law has a large time limit. Although (by construction) the incoming degree distributions depend on this law, this is not the case for most qualitative features concerning the size distribution of connected components, as long as the law has a finite variance. As the variance grows above 1/4, the average being < 1/2, a giant component emerges, which connects a finite fraction of the vertices. Below this threshold, the distribution of component sizes decreases algebraically with a continuously varying exponent. The transition is of infinite order, in sharp contrast with the case of static graphs. The local-in-time profiles for the components of finite size allow to give a refined description of the system.

  15. Molecular Dynamics Simulation of a Palmitoyl-Oleoyl Phosphatidylserine Bilayer with Na + Counterions and NaCl

    National Research Council Canada - National Science Library

    Mukhopadhyay, Parag; Monticelli, Luca; Tieleman, D. Peter

    2004-01-01

    ...) lipid bilayer in the liquid crystalline phase with Na(+) counterions and NaCl were carried out to investigate the structure of the negatively charged lipid bilayer and the effect of salt (NaCl...

  16. Random selection of Borel sets

    Directory of Open Access Journals (Sweden)

    Bernd Günther

    2010-10-01

    Full Text Available A theory of random Borel sets is presented, based on dyadic resolutions of compact metric spaces. The conditional expectation of the intersection of two independent random Borel sets is investigated. An example based on an embedding of Sierpinski’s universal curve into the space of Borel sets is given.

  17. Students' Misconceptions about Random Variables

    Science.gov (United States)

    Kachapova, Farida; Kachapov, Ilias

    2012-01-01

    This article describes some misconceptions about random variables and related counter-examples, and makes suggestions about teaching initial topics on random variables in general form instead of doing it separately for discrete and continuous cases. The focus is on post-calculus probability courses. (Contains 2 figures.)

  18. Forecasting Using Random Subspace Methods

    NARCIS (Netherlands)

    T. Boot (Tom); D. Nibbering (Didier)

    2016-01-01

    textabstractRandom subspace methods are a novel approach to obtain accurate forecasts in high-dimensional regression settings. We provide a theoretical justification of the use of random subspace methods and show their usefulness when forecasting monthly macroeconomic variables. We focus on two

  19. Developments in Random Matrix Theory

    OpenAIRE

    Snaith, N. C.; Forrester, P. J.; Verbaarschot, J. J. M.

    2003-01-01

    In this preface to the Journal of Physics A, Special Edition on Random Matrix Theory, we give a review of the main historical developments of random matrix theory. A short summary of the papers that appear in this special edition is also given.

  20. QCD and random matrix theory

    Energy Technology Data Exchange (ETDEWEB)

    Jackson, A.D. [Niels Bohr Inst., Copenhagen (Denmark)

    1998-08-10

    Chiral random matrix theory has recently been shown to provide a tool useful for both modeling chiral symmetry restoration in QCD and for providing analytic descriptions of the microscopic spectral content of lattice gauge simulations. The basic ideas of chiral random matrix theory and some recent results are discussed. (orig.) 24 refs.

  1. Perfil nutricional na artrite reumatoide

    Directory of Open Access Journals (Sweden)

    Rachel Simone Maccarini Zarpellon

    2014-01-01

    Full Text Available Objetivo: Estudar o perfil nutricional de pacientes com artrite reumatoide (AR. Métodos: Estudo transversal observacional de 102 pacientes com AR. Os pacientes foram estudados para dados clínicos, demográficos, sorológicos, atividade de doença e perfil nutricional. Neste último incluiu-se a medida do índice de massa corporal (IMC, relação quadril/cintura, pregas cutâneas bicipitais (PCB e sua adequação; prega cutânea tricipital (PCT e sua adequação e circunferência muscular do braço (CMB e sua adequação. Estudos de associação foram feitos usando os testes de Fisher e qui-quadrado para dados nominais e teste t não pareado e Mann Whitney para dados numéricos. Para cálculo de correlação usou-se o teste de Spearman. Resultado: Na amostra existiam 14/102 homens e 88/102 mulheres com idade média de 52,1 ± 11,5 anos e duração média de doença de 10,6 ± 7,4 anos. A relação cintura/quadril média era de 0,92 ± 0,07. De acordo com IMC, 30,3% tinham peso normal e 65,5% tinham peso acima do normal. De acordo com PCB, 74,5% eram normais e 25,5% tinham depleção; de acordo com a PCT, 83,3% eram normais e 16,7% tinham depleção. Associação de variáveis nutricionais com gênero, fator reumatoide, nódulos e atividade da doença não mostraram diferenças (p = NS exceto, por uma relação cintura/quadril menor em indivíduos com nódulos (p = 0,02 e uma correlação modesta da PCT com a duração de doença (p = 0,02; R = 0,22; 95% IC = 0,01-0,40. Conclusão: Existe uma alta prevalência de sobrepeso e obesidade em artrite reumatoide e uma pequena frequência de depleção muscular.

  2. RAZVOJ APLIKACIJE KINOTEKA NA MOBILNI PLATFORMI ANDROID

    OpenAIRE

    Cepec, Žiga

    2011-01-01

    Pametni mobilni telefoni in operacijski sistemi zanje so v zadnjih treh letih doživeli razcvet na področju mobilne telefonije. Operacijski sistem Android pridobiva na popularnosti in počasi prevzema vlogo vodilnega operacijskega sistema za mobilne naprave. Cilj diplomskega dela je spoznati platformo Android in razviti aplikacijo za operacijski sistem Android. V prvem delu diplomskega dela tako predstavljamo platformo Android, sam razvoj, sestavne elemente in tudi arhitekturo operacijskega sis...

  3. Sodium sulfur technology program NaSTEC

    Science.gov (United States)

    Highley, Bob; Somerville, W. Andrew

    The NaSTEC program focuses on developing currently available sodium sulfur cells for use in space applications and investigating the operational parameters of the cells. The specific goals of the program are to determine the operational parameters and verify safety limits of Na/S technology battery cells; test long term zero-g operation; and create a life test database. The program approach and ground and flight test objectives are described in textual and graphic form.

  4. a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    MS Yıldırım

    2016-02-01

    Full Text Available The aim of this study was to compare the effects of static stretching, proprioceptive neuromuscular facilitation (PNF stretching and Mulligan technique on hip flexion range of motion (ROM in subjects with bilateral hamstring tightness. A total of 40 students (mean age: 21.5±1.3 years, mean body height: 172.8±8.2 cm, mean body mass index: 21.9±3.0 kg • m-2 with bilateral hamstring tightness were enrolled in this randomized trial, of whom 26 completed the study. Subjects were divided into 4 groups performing (I typical static stretching, (II PNF stretching, (III Mulligan traction straight leg raise (TSLR technique, (IV no intervention. Hip flexion ROM was measured using a digital goniometer with the passive straight leg raise test before and after 4 weeks by two physiotherapists blinded to the groups. 52 extremities of 26 subjects were analyzed. Hip flexion ROM increased in all three intervention groups (p<0.05 but not in the no-intervention group after 4 weeks. A statistically significant change in initial–final assessment differences of hip flexion ROM was found between groups (p<0.001 in favour of PNF stretching and Mulligan TSLR technique in comparison to typical static stretching (p=0.016 and p=0.02, respectively. No significant difference was found between Mulligan TSLR technique and PNF stretching (p=0.920. The initial–final assessment difference of hip flexion ROM was similar in typical static stretching and no intervention (p=0.491. A 4-week stretching intervention is beneficial for increasing hip flexion ROM in bilateral hamstring tightness. However, PNF stretching and Mulligan TSLR technique are superior to typical static stretching. These two interventions can be alternatively used for stretching in hamstring tightness.

  5. Excess Enthalpies of Mixing of Binary Mixtures of NaCl, KCl, NaBr ...

    African Journals Online (AJOL)

    NJD

    2004-07-01

    Jul 1, 2004 ... bDepartment of Chemical Engineering, Yonsei University, Seoul 120-749, Korea. ... interactions play a key role in the solution chemistry of solutes.1–6 ..... I = 1.000 mol kg–1. KBr (1) + KCl (2). NaBr (1) + NaCl (2). KBr (1) + NaCl (2). 0.1093. 22. 0.1208. 10. 0.1128. 19. 0.1582. 36. 0.2118. 14. 0.1818. 28.

  6. Quasi-Random Rumor Spreading: Reducing Randomness Can Be Costly

    OpenAIRE

    Doerr, Benjamin; Fouz, Mahmoud

    2010-01-01

    We give a time-randomness tradeoff for the quasi-random rumor spreading protocol proposed by Doerr, Friedrich and Sauerwald [SODA 2008] on complete graphs. In this protocol, the goal is to spread a piece of information originating from one vertex throughout the network. Each vertex is assumed to have a (cyclic) list of its neighbors. Once a vertex is informed by one of its neighbors, it chooses a position in its list uniformly at random and then informs its neighbors starting from that positi...

  7. Respiratorni simptomi u radnica na preradi riba na obali Jadrana u Hrvatskoj

    OpenAIRE

    Žuškin, Eugenija; Kern, Josipa; Mustajbegović, Jadranka; Pucarin-Cvetković, Jasna; Doko-Jelinić, Jagoda; Bradić, Tihomir

    2012-01-01

    Cilj je ovoga istraživanja bio ispitati respiratorne simptome i plućnu funkciju radnica zaposlenih na preradi riba u industriji na obali Jadranskog mora u Hrvatskoj. U istraživanje je uključeno 98 radnica zaposlenih na preradi riba i 95 žena neizložene kontrolne skupine. Ispitivani su kronični i akutni respiratorni simptomi koji se razvijaju tijekom radne smjene. Mjerena je plućna funkcija registriranjem forsiranoga vitalnog kapaciteta (FVC), forsiranoga ekspiracijskog volumena u prvoj sekund...

  8. Humanismo de Funcionamento Pleno: tendência formativa na abordagem centrada na pessoa

    OpenAIRE

    Gonçalves, Bruno; Faculdade Anhanguera de Jundiaí

    2012-01-01

    O livro Humanismo de Funcionamento Pleno: Tendência Formativa na Abordagem Centrada na Pessoa - ACP, é uma coletânea de textos organizados por Francisco Silva Cavalcante Junior e André Feitosa de Souza, que integra a coleção literária Humanismo e Salutogênese trazendo a proposta, de re-humanizar a psicologia, conforme menciona Poland (2008) na introdução do volume e avançar na discussão sobre Tendência Formativa e suas expressões, preenchendo o vazio deixado por muitos anos de esquecimento da...

  9. Clues to NaCN formation

    Science.gov (United States)

    Quintana-Lacaci, G.; Cernicharo, J.; Velilla Prieto, L.; Agúndez, M.; Castro-Carrizo, A.; Fonfría, J. P.; Massalkhi, S.; Pardo, J. R.

    2017-11-01

    Context. ALMA is providing us essential information on where certain molecules form. Observing where these molecules emission arises from, the physical conditions of the gas, and how this relates with the presence of other species allows us to understand the formation of many species, and to significantly improve our knowledge of the chemistry that occurs in the space. Aims: We studied the molecular distribution of NaCN around IRC +10216, a molecule detected previously, but whose origin is not clear. High angular resolution maps allow us to model the abundance distribution of this molecule and check suggested formation paths. Methods: We modeled the emission of NaCN assuming local thermal equilibrium (LTE) conditions. These profiles were fitted to azimuthal averaged intensity profiles to obtain an abundance distribution of NaCN. Results: We found that the presence of NaCN seems compatible with the presence of CN, probably as a result of the photodissociation of HCN, in the inner layers of the ejecta of IRC +10216. However, similar as for CH3CN, current photochemical models fail to reproduce this CN reservoir. We also found that the abundance peak of NaCN appears at a radius of 3 × 1015 cm, approximately where the abundance of NaCl, suggested to be the parent species, starts to decay. However, the abundance ratio shows that the NaCl abundance is lower than that obtained for NaCN. We expect that the LTE assumption might result in NaCN abundances higher than the real ones. Updated photochemical models, collisional rates, and reaction rates are essential to determine the possible paths of the NaCN formation. Based on observations carried out with ALMA and the IRAM 30 m Telescope. ALMA is a partnership of ESO (representing its member states), NSF (USA) and NINS (Japan), together with NRC (Canada) and NSC and ASIAA (Taiwan), in cooperation with the Republic of Chile. The Joint ALMA Observatory is operated by ESO, AUI/NRAO and NAOJ. IRAM is supported by INSU/CNRS (France

  10. Influence of sodium halides (NaF, NaCl, NaBr, NaI) on the photocatalytic performance of hydrothermally synthesized hematite photoanodes.

    Science.gov (United States)

    Wang, Tsinghai; Huang, Mao-Chia; Hsieh, Yi-Kong; Chang, Wen-Sheng; Lin, Jing-Chie; Lee, Chih-Hao; Wang, Chu-Fang

    2013-08-28

    It has been suggested that a high concentration of Fe(3+) in solution, a low pH, and noncomplexing ions of high ionic strength are all essential for developing a high-quality hematite array. Our curiosity was piqued regarding the role of the electrolyte ions in the hydrothermal synthesis of hematite photoanodes. In this study, we prepared hematite photoanodes hydrothermally from precursor solutions of 0.1 M FeCl3 at pH 1.55 with a background electrolyte of 1.0 M sodium halide (NaF, NaCl, NaBr, or NaI). We compared the structures and properties of the as-obtained hematite photoanodes with those of the material prepared in 1.0 M NaNO3, the most widely adopted electrolyte in previous studies. Among our studied systems, we found that the hematite photoanode prepared in NaCl solution was the only one possessing properties similar to those of the sample obtained from the NaNO3 solution-most importantly in terms of photoelectrochemical performance (ca. 0.2 mA/cm(2) with +0.4 V vs SCE). The hematites obtained from the NaF, NaBr, and NaI solutions exhibited much lower (by approximately 2 orders of magnitude) photocurrent densities under the same conditions, possibly because of their relatively less ordered crystallinity and the absence of rodlike morphologies. Because the synthetic protocol was identical in each case, we believe that these two distinct features reflect the environments in which these hematite photoanodes were formed. Consistent with the latest studies reported in the literature of the X-ray photoelectron spectra of fast-frozen hematite colloids in aqueous solutions, it appears that the degree of surface ion loading at the electrolyte-hematite interface (Stern layer) is critical during the development of hematite photoanodes. We suspect that a lower ion surface loading benefits the hematite developing relatively higher-order and a rodlike texture, thereby improving the photoelectrochemical activity.

  11. Thermodynamics of random number generation

    Science.gov (United States)

    Aghamohammadi, Cina; Crutchfield, James P.

    2017-06-01

    We analyze the thermodynamic costs of the three main approaches to generating random numbers via the recently introduced Information Processing Second Law. Given access to a specified source of randomness, a random number generator (RNG) produces samples from a desired target probability distribution. This differs from pseudorandom number generators (PRNGs) that use wholly deterministic algorithms and from true random number generators (TRNGs) in which the randomness source is a physical system. For each class, we analyze the thermodynamics of generators based on algorithms implemented as finite-state machines, as these allow for direct bounds on the required physical resources. This establishes bounds on heat dissipation and work consumption during the operation of three main classes of RNG algorithms—including those of von Neumann, Knuth, and Yao and Roche and Hoshi—and for PRNG methods. We introduce a general TRNG and determine its thermodynamic costs exactly for arbitrary target distributions. The results highlight the significant differences between the three main approaches to random number generation: One is work producing, one is work consuming, and the other is potentially dissipation neutral. Notably, TRNGs can both generate random numbers and convert thermal energy to stored work. These thermodynamic costs on information creation complement Landauer's limit on the irreducible costs of information destruction.

  12. An introduction to random sets

    CERN Document Server

    Nguyen, Hung T

    2006-01-01

    The study of random sets is a large and rapidly growing area with connections to many areas of mathematics and applications in widely varying disciplines, from economics and decision theory to biostatistics and image analysis. The drawback to such diversity is that the research reports are scattered throughout the literature, with the result that in science and engineering, and even in the statistics community, the topic is not well known and much of the enormous potential of random sets remains untapped.An Introduction to Random Sets provides a friendly but solid initiation into the theory of random sets. It builds the foundation for studying random set data, which, viewed as imprecise or incomplete observations, are ubiquitous in today''s technological society. The author, widely known for his best-selling A First Course in Fuzzy Logic text as well as his pioneering work in random sets, explores motivations, such as coarse data analysis and uncertainty analysis in intelligent systems, for studying random s...

  13. True Randomness from Big Data

    Science.gov (United States)

    Papakonstantinou, Periklis A.; Woodruff, David P.; Yang, Guang

    2016-09-01

    Generating random bits is a difficult task, which is important for physical systems simulation, cryptography, and many applications that rely on high-quality random bits. Our contribution is to show how to generate provably random bits from uncertain events whose outcomes are routinely recorded in the form of massive data sets. These include scientific data sets, such as in astronomics, genomics, as well as data produced by individuals, such as internet search logs, sensor networks, and social network feeds. We view the generation of such data as the sampling process from a big source, which is a random variable of size at least a few gigabytes. Our view initiates the study of big sources in the randomness extraction literature. Previous approaches for big sources rely on statistical assumptions about the samples. We introduce a general method that provably extracts almost-uniform random bits from big sources and extensively validate it empirically on real data sets. The experimental findings indicate that our method is efficient enough to handle large enough sources, while previous extractor constructions are not efficient enough to be practical. Quality-wise, our method at least matches quantum randomness expanders and classical world empirical extractors as measured by standardized tests.

  14. Quasi-solid state rechargeable Na-CO2 batteries with reduced graphene oxide Na anodes.

    Science.gov (United States)

    Hu, Xiaofei; Li, Zifan; Zhao, Yaran; Sun, Jianchao; Zhao, Qing; Wang, Jianbin; Tao, Zhanliang; Chen, Jun

    2017-02-01

    Na-CO2 batteries using earth-abundant Na and greenhouse gas CO2 are promising tools for mobile and stationary energy storage, but they still pose safety risks from leakage of liquid electrolyte and instability of the Na metal anode. These issues result in extremely harsh operating conditions of Na-CO2 batteries and increase the difficulty of scaling up this technology. We report the development of quasi-solid state Na-CO2 batteries with high safety using composite polymer electrolyte (CPE) and reduced graphene oxide (rGO) Na anodes. The CPE of PVDF-HFP [poly(vinylidene fluoride-co-hexafluoropropylene)]-4% SiO2/NaClO4-TEGDME (tetraethylene glycol dimethyl ether) has high ion conductivity (1.0 mS cm(-1)), robust toughness, a nonflammable matrix, and strong electrolyte-locking ability. In addition, the rGO-Na anode presents fast and nondendritic Na(+) plating/stripping (5.7 to 16.5 mA cm(-2)). The improved kinetics and safety enable the constructed rGO-Na/CPE/CO2 batteries to successfully cycle in wide CO2 partial pressure window (5 to 100%, simulated car exhaust) and especially to run for 400 cycles at 500 mA g(-1) with a fixed capacity of 1000 mA·hour g(-1) in pure CO2. Furthermore, we scaled up the reversible capacity to 1.1 A·hour in pouch-type batteries (20 × 20 cm, 10 g, 232 Wh kg(-1)). This study makes quasi-solid state Na-CO2 batteries an attractive prospect.

  15. Combined 18F-NaF and 18F-FDG PET/CT in the Evaluation of Sarcoma Patients.

    Science.gov (United States)

    Jackson, Tatianie; Mosci, Camila; von Eyben, Rie; Mittra, Erik; Ganjoo, Kristen; Biswal, Sandip; Gambhir, Sanjiv Sam; Iagaru, Andrei

    2015-09-01

    The combined administration of F-NaF and F-FDG in a single PET/CT scan has the potential to improve patient convenience and cancer detection. Here we report the use of this approach for patients with sarcomas. This is a retrospective review of 21 patients (12 men, 9 women; age, 19-66 years) with biopsy-proven sarcomas who had separate F-NaF PET/CT, F-FDG PET/CT, and combined F-NaF/F-FDG PET/CT scans for evaluation of malignancy. Two board-certified nuclear medicine physicians and 1 board-certified musculoskeletal radiologist were randomly assigned to review the scans. Results were analyzed for sensitivity and specificity, using linear regression and receiver operating characteristics. A total of 13 patients had metastatic disease on F-NaF PET/CT, F-FDG PET/CT, and combined F-NaF/F-FDG PET/CT. Skeletal disease was more extensive on the F-NaF PET/CT scan than on the F-FDG PET/CT in 3 patients, whereas in 1 patient, F-FDG PET/CT showed skeletal disease and the F-NaF PET/CT was negative. Extraskeletal lesions were detected on both F-FDG and combined F-NaF/F-FDG PET/CT in 20 patients, with 1 discordant finding in the lung. The combined F-NaF/F-FDG PET/CT scan allows for accurate evaluation of sarcoma patients. Further evaluation of this proposed imaging modality is warranted to identify the most suitable clinical scenarios, including initial treatment strategy and evaluation of response to therapy.

  16. Random processes in nuclear reactors

    CERN Document Server

    Williams, M M R

    1974-01-01

    Random Processes in Nuclear Reactors describes the problems that a nuclear engineer may meet which involve random fluctuations and sets out in detail how they may be interpreted in terms of various models of the reactor system. Chapters set out to discuss topics on the origins of random processes and sources; the general technique to zero-power problems and bring out the basic effect of fission, and fluctuations in the lifetime of neutrons, on the measured response; the interpretation of power reactor noise; and associated problems connected with mechanical, hydraulic and thermal noise sources

  17. Characterization of nonstationary random processes

    Energy Technology Data Exchange (ETDEWEB)

    Paez, T.L.

    1985-01-01

    Current methods for shock test specification and shock testing treat the shock environment as a deterministic source. The present study proposes to treat shock sources as nonstationary random processes. A model for a realistic nonstationary random process shock source is specified, and the effect of variation of parameters in the shock source is shown. A method for estimating the parameters of the random process is established, and some numerical examples show that the method yields reasonable results. The use of this model in shock testing is discussed.

  18. Symmetrization of binary random variables

    OpenAIRE

    Kagan, Abram; Mallows, Colin L.; Shepp, Larry A.; Vanderbei, Robert J.; Vardi, Yehuda

    1999-01-01

    A random variable [math] is called an independent symmetrizer of a given random variable [math] if (a) it is independent of [math] and (b) the distribution of [math] is symmetric about [math] . In cases where the distribution of [math] is symmetric about its mean, it is easy to see that the constant random variable [math] is a minimum-variance independent symmetrizer. Taking [math] to have the same distribution as [math] clearly produces a symmetric sum, but it may not be of minimum variance....

  19. Upravljanje proizvodnom jedinicom spojenom na mrežu tijekom nesimetričnih napona na mreži temeljeno na kliznom režimu

    OpenAIRE

    Mahdi Rezaei, Mohammad; Soltani, Jafar

    2016-01-01

    Povećanje udjela distribuiranih proizvodnih jedinica povezanih na mrežu frekvencijskim pretvaračima zahtjeva metode upravljanja koje dobro djeluju tijekom normalnih uvjeta na mreži kao i u nesimetričnim uvjetima. Najčešći tip nesimetričnog napona na distribuiranoj jedinici je nesimetrična amplituda trofaznog napona na fundamentalnoj frekvenciji. To se događa privremeno zbog kvarova ili trajno zbog nejednake distribucije nesimetričnih tereta na tri faze distribuirane proizvodne jedinice. U ovo...

  20. O Passeio Público do Rio de Janeiro na Literatura, na Pintura e na Fotografia do Século XIX

    Directory of Open Access Journals (Sweden)

    Solange de Aragão

    2012-06-01

    Full Text Available Este artigo tem como objetivo geral e mais amplo chamar a atenção dos pesquisadores para a importância da literatura, da pintura e da fotografia como fontes documentais para a construção da História do Paisagismo no Brasil por meio de um estudo de caso muito particular: o Passeio Público do Rio de Janeiro no século XIX. São objetivos específicos apresentar e analisar o modo como esse espaço livre público aparece na literatura, na pintura e na fotografia desse período, considerando suas transformações paisagísticas.

  1. Mabadiliko Ya Kifonolojia Na Kimofolojia Wakati Wa Utohozi Wa ...

    African Journals Online (AJOL)

    Mwingiliano wa lugha ya Kiswahili na Kiarabu una historia ndefu kidogo. Inasemekana Waarabu walianza muwasala na 'Waswahili' tangu karne ya kwanza (BK) (Polome 1967:9). Kutokana na muwasala huo wa muda mrefu, lugha hizi mbili (Kiarabu na Kiswahili) zimeathiriana sana. Lakini kuna maoni kwamba Kiarabu ...

  2. Ujanibishaji wa Office 2003 na Windows XP kwa Kiswahili Sanifu ...

    African Journals Online (AJOL)

    Mradi wa ujanibishaji wa Office 2003 na Windows XP kwa Kiswahili sanifu ulitekelezwa katika kipindi 2004-2005. Malengo ya mradi yalikuwa: (1) kuandaa istilahi za kompyuta kwa Kiingereza-Kiswahili, na (2) kutafsiri programu nne za kawaida za Office (Outlook, Excel, Word na PowerPoint) na Windows XP. Makala hii ina ...

  3. Crescimento da base craniana nos diferentes tipos faciais nos relacionamentos maxilomandibulares ortopédicos de Classe I, II e III: Parte 2 (Crescimento médio de Ba-Na, CC-Na e CC-Ba Cranial base growth in different facial types in Class I, II and III orthopedic maxillomandibular relationship: Part 2 (Mean growth of Ba-Na, CC-Na and CC-Ba

    Directory of Open Access Journals (Sweden)

    Lucelma Vilela Pieri

    2007-04-01

    Full Text Available OBJETIVO: este estudo retrospectivo avaliou o crescimento médio da base craniana nos diferentes tipos faciais e de relacionamentos maxilomandibulares ortopédicos.METODOLOGIA: uma amostra aleatória de 300 pacientes brasileiros leucodermas (131 do gênero masculino, 169 do gênero feminino, com idade média inicial de 10 anos e 2 meses (dentadura mista e final de 14 anos e 8 meses (segundos molares em oclusão e tempo médio de observação de 4 anos e 5 meses, foi selecionada em uma clínica particular, em São Paulo, Brasil. Havia 118 Classe I, 151 Classe II e 31 Classe III. Todas as 600 radiografias cefalométricas laterais foram obtidas no mesmo aparelho de raios-x. As análises de Ricketts e Schwarz modificadas por Faltin foram usadas. As medidas lineares (Ba-Na, CC-Na e CC-Ba foram feitas manualmente pelo mesmo examinador em T1 e T2. Os relacionamentos foram estudados juntos e separadamente, considerando tipo facial e gênero. O teste t-pareado e ANOVA foram aplicados. RESULTADOS E CONCLUSÕES: o tipo facial retrovertido cresceu significantemente mais em CC-Na na Classe II, sendo a sua correção desfavorável no gênero feminino; com tendência favorável na Classe III e crescimento dentro do esperado na Classe I. O neutrovertido cresceu significantemente mais em CC-Na nas Classes I e II, sendo desfavorável na Classe II; com crescimento eqüitativo de CC-Na e CC-Ba na Classe III e levemente acima do esperado na Classe I. O provertido teve crescimento eqüitativo em todas as Classes, sendo significantemente favorável na Classe II mandibular; com tendência favorável na Classe III e crescimento médio acima do esperado na Classe I.AIM: This retrospective study evaluated the cranial base mean growth in different facial types and orthopedic maxillomandibular relationship. METHODS: A random sample of 300 Brazilian Caucasian patients (131 males, 169 females, initial and final mean age (10 years 2 months-mixed dentition; 14 years 8 months

  4. Glutamate Water Gates in the Ion Binding Pocket of Na(+) Bound Na(+), K(+)-ATPase

    DEFF Research Database (Denmark)

    Han, Minwoo; Kopec, Wojciech; Solov'yov, Ilia A

    2017-01-01

    The dynamically changing protonation states of the six acidic amino acid residues in the ion binding pocket of the Na(+), K(+) -ATPase (NKA) during the ion transport cycle are proposed to drive ion binding, release and possibly determine Na(+) or K(+) selectivity. We use molecular dynamics (MD) a...

  5. A coprecipitation technique to prepare NaNbO3 and NaTaO3

    Indian Academy of Sciences (India)

    Unknown

    the more successful wet-chemical techniques for synthe- sizing ultrafine ceramic powders having narrow particle size distribution (Dhage et al 2003; Gaikwad et al 2004,. 2005a, b). The purpose of this study was to prepare ultra- fine NaNbO3 and NaTaO3 powders using the co-preci- pitation technique from simple water ...

  6. Excess Enthalpies of Mixing of Binary Mixtures of NaCl, KCl, NaBr ...

    African Journals Online (AJOL)

    NJD

    2004-07-01

    Jul 1, 2004 ... Excess enthalpies of mixing for six possible binary combinations of solutions of NaCl, KCl, NaBr and KBr in mixed ternary solvents composed of ... practical interest for industrial and geochemical applications. Interest in ... Pitzer,11–16 where the excess Gibbs energy of the system is repre- sented by a ...

  7. Electromagnetic scattering from random media

    CERN Document Server

    Field, Timothy R

    2009-01-01

    - ;The book develops the dynamical theory of scattering from random media from first principles. Its key findings are to characterize the time evolution of the scattered field in terms of stochastic differential equations, and to illustrate this framework

  8. Random walks on reductive groups

    CERN Document Server

    Benoist, Yves

    2016-01-01

    The classical theory of Random Walks describes the asymptotic behavior of sums of independent identically distributed random real variables. This book explains the generalization of this theory to products of independent identically distributed random matrices with real coefficients. Under the assumption that the action of the matrices is semisimple – or, equivalently, that the Zariski closure of the group generated by these matrices is reductive - and under suitable moment assumptions, it is shown that the norm of the products of such random matrices satisfies a number of classical probabilistic laws. This book includes necessary background on the theory of reductive algebraic groups, probability theory and operator theory, thereby providing a modern introduction to the topic.

  9. Octonions in random matrix theory

    Science.gov (United States)

    Forrester, Peter J.

    2017-04-01

    The octonions are one of the four normed division algebras, together with the real, complex and quaternion number systems. The latter three hold a primary place in random matrix theory, where in applications to quantum physics they are determined as the entries of ensembles of Hermitian random matrices by symmetry considerations. Only for N=2 is there an existing analytic theory of Hermitian random matrices with octonion entries. We use a Jordan algebra viewpoint to provide an analytic theory for N=3. We then proceed to consider the matrix structure X†X, when X has random octonion entries. Analytic results are obtained from N=2, but are observed to break down in the 3×3 case.

  10. Cluster randomization and political philosophy.

    Science.gov (United States)

    Chwang, Eric

    2012-11-01

    In this paper, I will argue that, while the ethical issues raised by cluster randomization can be challenging, they are not new. My thesis divides neatly into two parts. In the first, easier part I argue that many of the ethical challenges posed by cluster randomized human subjects research are clearly present in other types of human subjects research, and so are not novel. In the second, more difficult part I discuss the thorniest ethical challenge for cluster randomized research--cases where consent is genuinely impractical to obtain. I argue that once again these cases require no new analytic insight; instead, we should look to political philosophy for guidance. In other words, the most serious ethical problem that arises in cluster randomized research also arises in political philosophy. © 2011 Blackwell Publishing Ltd.

  11. Quantifying randomness in real networks

    Science.gov (United States)

    Orsini, Chiara; Dankulov, Marija M.; Colomer-de-Simón, Pol; Jamakovic, Almerima; Mahadevan, Priya; Vahdat, Amin; Bassler, Kevin E.; Toroczkai, Zoltán; Boguñá, Marián; Caldarelli, Guido; Fortunato, Santo; Krioukov, Dmitri

    2015-10-01

    Represented as graphs, real networks are intricate combinations of order and disorder. Fixing some of the structural properties of network models to their values observed in real networks, many other properties appear as statistical consequences of these fixed observables, plus randomness in other respects. Here we employ the dk-series, a complete set of basic characteristics of the network structure, to study the statistical dependencies between different network properties. We consider six real networks--the Internet, US airport network, human protein interactions, technosocial web of trust, English word network, and an fMRI map of the human brain--and find that many important local and global structural properties of these networks are closely reproduced by dk-random graphs whose degree distributions, degree correlations and clustering are as in the corresponding real network. We discuss important conceptual, methodological, and practical implications of this evaluation of network randomness, and release software to generate dk-random graphs.

  12. Na/K pump inactivation, subsarcolemmal Na measurements, and cytoplasmic ion turnover kinetics contradict restricted Na spaces in murine cardiac myocytes.

    Science.gov (United States)

    Lu, Fang-Min; Hilgemann, Donald W

    2017-07-03

    Decades ago, it was proposed that Na transport in cardiac myocytes is modulated by large changes in cytoplasmic Na concentration within restricted subsarcolemmal spaces. Here, we probe this hypothesis for Na/K pumps by generating constitutive transsarcolemmal Na flux with the Na channel opener veratridine in whole-cell patch-clamp recordings. Using 25 mM Na in the patch pipette, pump currents decay strongly during continuous activation by extracellular K (τ, ∼2 s). In contradiction to depletion hypotheses, the decay becomes stronger when pump currents are decreased by hyperpolarization. Na channel currents are nearly unchanged by pump activity in these conditions, and conversely, continuous Na currents up to 0.5 nA in magnitude have negligible effects on pump currents. These outcomes are even more pronounced using 50 mM Li as a cytoplasmic Na congener. Thus, the Na/K pump current decay reflects mostly an inactivation mechanism that immobilizes Na/K pump charge movements, not cytoplasmic Na depletion. When channel currents are increased beyond 1 nA, models with unrestricted subsarcolemmal diffusion accurately predict current decay (τ ∼15 s) and reversal potential shifts observed for Na, Li, and K currents through Na channels opened by veratridine, as well as for Na, K, Cs, Li, and Cl currents recorded in nystatin-permeabilized myocytes. Ion concentrations in the pipette tip (i.e., access conductance) track without appreciable delay the current changes caused by sarcolemmal ion flux. Importantly, cytoplasmic mixing volumes, calculated from current decay kinetics, increase and decrease as expected with osmolarity changes (τ >30 s). Na/K pump current run-down over 20 min reflects a failure of pumps to recover from inactivation. Simulations reveal that pump inactivation coupled with Na-activated recovery enhances the rapidity and effectivity of Na homeostasis in cardiac myocytes. In conclusion, an autoregulatory mechanism enhances cardiac Na/K pump activity when

  13. Random sequential adsorption of cubes.

    Science.gov (United States)

    Cieśla, Michał; Kubala, Piotr

    2018-01-14

    Random packings built of cubes are studied numerically using a random sequential adsorption algorithm. To compare the obtained results with previous reports, three different models of cube orientation sampling were used. Also, three different cube-cube intersection algorithms were tested to find the most efficient one. The study focuses on the mean saturated packing fraction as well as kinetics of packing growth. Microstructural properties of packings were analyzed using density autocorrelation function.

  14. Growing random networks with fitness

    OpenAIRE

    Ergun, G.; Rodgers, GJ

    2001-01-01

    Three models of growing random networks with fitness dependent growth rates are analysed using the rate equations for the distribution of their connectivities. In the first model (A), a network is built by connecting incoming nodes to nodes of connectivity $k$ and random additive fitness $\\eta$, with rate $(k-1)+ \\eta $. For $\\eta >0$ we find the connectivity distribution is power law with exponent $\\gamma=+2$. In the second model (B), the network is built by connecting nodes to nodes of conn...

  15. Large Deviations for Random Trees.

    Science.gov (United States)

    Bakhtin, Yuri; Heitsch, Christine

    2008-08-01

    We consider large random trees under Gibbs distributions and prove a Large Deviation Principle (LDP) for the distribution of degrees of vertices of the tree. The LDP rate function is given explicitly. An immediate consequence is a Law of Large Numbers for the distribution of vertex degrees in a large random tree. Our motivation for this study comes from the analysis of RNA secondary structures.

  16. Randomness in Contemporary Graphic Art

    OpenAIRE

    Zavřelová, Veronika

    2016-01-01

    Veronika Zavřelová Bachelor thesis Charles University in Prague, Faculty of Education, Department of Art Education Randomness in contemporary graphic art imaginative picture card game ANNOTATION This (bachelor) thesis concerns itself with a connection between verbal and visual character system within the topic of Randomness in contemporary graphic art - imaginative picture card game. The thesis is mainly based on the practical part - exclusively created card game Piktim. The card game uses as...

  17. Influencia dos hormonios tireoidianos na densidade ossea e na periodontite : estudo em ratos

    OpenAIRE

    Daniela da Silva Feitosa

    2009-01-01

    Resumo: Os hormônios tireoidianos desempenham um papel crítico no metabolismo ósseo. Entretanto, dados relacionados ao efeito das alterações nos níveis destes hormônios na densidade mineral óssea mandibular e na progressão da doença periodontal são limitados. O objetivo do presente estudo foi avaliar, em ratos, a influência de diferentes níveis séricos dos hormônios tireoidianos: (1) na densidade radiográfica e na proporção dos componentes cortical e medular na mandíbula em comparação com a t...

  18. Summer sudden Na number density enhancements measured with the ALOMAR Weber Na Lidar

    Directory of Open Access Journals (Sweden)

    D. Heinrich

    2008-05-01

    Full Text Available We present summer Na-densities and atmospheric temperatures measured 80 to 110 km above the Arctic Lidar Observatory for Middle Atmosphere Research (ALOMAR. The Weber Na Lidar is part of ALOMAR, located at 69° N in Norway, 150 km north of the Arctic Circle. The sun does not set here during the summer months, and measurements require a narrowband Faraday Anomalous Dispersion Optical Filter (FADOF.

    We discuss an observed sudden enhancement in the Na number density around 22:00 UT on 1 to 2 June 2006. We compare this observation with previous summer measurements and find a frequent appearance of Na number density enhancements near local midnight. We describe the time of appearance, the altitude distribution, the duration and the strength of these enhancements and compare them to winter observations. We investigate possible formation mechanisms and, as others before, we find a strong link between these Na number density enhancements and sporadic E layers.

  19. Summer sudden Na number density enhancements measured with the ALOMAR Weber Na Lidar

    Directory of Open Access Journals (Sweden)

    D. Heinrich

    2008-05-01

    Full Text Available We present summer Na-densities and atmospheric temperatures measured 80 to 110 km above the Arctic Lidar Observatory for Middle Atmosphere Research (ALOMAR. The Weber Na Lidar is part of ALOMAR, located at 69° N in Norway, 150 km north of the Arctic Circle. The sun does not set here during the summer months, and measurements require a narrowband Faraday Anomalous Dispersion Optical Filter (FADOF. We discuss an observed sudden enhancement in the Na number density around 22:00 UT on 1 to 2 June 2006. We compare this observation with previous summer measurements and find a frequent appearance of Na number density enhancements near local midnight. We describe the time of appearance, the altitude distribution, the duration and the strength of these enhancements and compare them to winter observations. We investigate possible formation mechanisms and, as others before, we find a strong link between these Na number density enhancements and sporadic E layers.

  20. Metallic Na formation in NaCl crystals with irradiation of electron or vacuum ultraviolet photon

    Energy Technology Data Exchange (ETDEWEB)

    Owaki, Shigehiro [Osaka Prefecture Univ., Sakai, Osaka (Japan). Coll. of Integrated Arts and Sciences; Koyama, Shigeko; Takahashi, Masao; Kamada, Masao; Suzuki, Ryouichi

    1997-03-01

    Metallic Na was formed in NaCl single crystals with irradiation of a variety of radiation sources and analyzed the physical states with several methods. In the case of irradiation of 21 MeV electron pulses to the crystal blocks, the optical absorption and lifetime measurement of positron annihilation indicated appearance of Na clusters inside. Radiation effects of electron beam of 30 keV to the crystals in vacuum showed the appearance of not only metallic Na but atomic one during irradiation with Auger electron spectroscopy. Intense photon fluxes in vacuum ultraviolet region of synchrotron radiation were used as another source and an analyzing method of ultraviolet photoelectron spectroscopy. The results showed the metallic Na layered so thick that bulk plasmon can exist. (author)

  1. Hydrolysis of Rice Straw Pretreated by Na2SO3 Over Fe-resin/NaCl

    Directory of Open Access Journals (Sweden)

    YANG Hui

    2017-05-01

    Full Text Available To increase the conversion of rice straw(RS and the yield of products, we employed three methods, which were ultrasonic wave, steam explosion and Na2SO3 pretreatment to pretreat RS(the treated RS noted as CS-RS, ZQ-RS and Na2SO3-RS, respectively and found that Na2SO3 treatment was the best pretreatment method based on XRD, SEM, elemental analysis and content of cellulose, hemicellulose and lignin. The conversion of Na2SO3-RS and the yield of total reducing sugar(TRS and levulinic acid(LA were 97.3%, 29.6% and 13.5%, respectively by 10% Fe-resin in 3.3% NaCl solution under 200 ℃.

  2. Changes in Intracellular Na+ following Enhancement of Late Na+ Current in Virtual Human Ventricular Myocytes

    Science.gov (United States)

    Giles, Wayne R.

    2016-01-01

    The slowly inactivating or late Na+ current, INa-L, can contribute to the initiation of both atrial and ventricular rhythm disturbances in the human heart. However, the cellular and molecular mechanisms that underlie these pro-arrhythmic influences are not fully understood. At present, the major working hypothesis is that the Na+ influx corresponding to INa-L significantly increases intracellular Na+, [Na+]i; and the resulting reduction in the electrochemical driving force for Na+ reduces and (may reverse) Na+/Ca2+ exchange. These changes increase intracellular Ca2+, [Ca2+]i; which may further enhance INa-L due to calmodulin-dependent phosphorylation of the Na+ channels. This paper is based on mathematical simulations using the O’Hara et al (2011) model of baseline or healthy human ventricular action potential waveforms(s) and its [Ca2+]i homeostasis mechanisms. Somewhat surprisingly, our results reveal only very small changes (≤ 1.5 mM) in [Na+]i even when INa-L is increased 5-fold and steady-state stimulation rate is approximately 2 times the normal human heart rate (i.e. 2 Hz). Previous work done using well-established models of the rabbit and human ventricular action potential in heart failure settings also reported little or no change in [Na+]i when INa-L was increased. Based on our simulations, the major short-term effect of markedly augmenting INa-L is a significant prolongation of the action potential and an associated increase in the likelihood of reactivation of the L-type Ca2+ current, ICa-L. Furthermore, this action potential prolongation does not contribute to [Na+]i increase. PMID:27875582

  3. Functional coupling of renal K+ and Na+ handling causes high blood pressure in Na+ replete mice.

    Science.gov (United States)

    Vitzthum, Helga; Seniuk, Anika; Schulte, Laura Helene; Müller, Maxie Luise; Hetz, Hannah; Ehmke, Heimo

    2014-03-01

    A network of kinases, including WNKs, SPAK and Sgk1, is critical for the independent regulation of K+ and Na+ transport in the distal nephron. Angiotensin II is thought to act as a key hormone in orchestrating these kinases to switch from K+ secretion during hyperkalaemia to Na+ reabsorption during intravascular volume depletion, thus keeping disturbances in electrolyte and blood pressure homeostasis at a minimum. It remains unclear, however, how K+ and Na+ transport are regulated during a high Na+ intake, which is associated with suppressed angiotensin II levels and a high distal tubular Na+ load. We therefore investigated the integrated blood pressure, renal, hormonal and gene and protein expression responses to large changes of K+ intake in Na+ replete mice. Both low and high K+ intake increased blood pressure and caused Na+ retention. Low K+ intake was accompanied by an upregulation of the sodium-chloride cotransporter (NCC) and its activating kinase SPAK, and inhibition of NCC normalized blood pressure. Renal responses were unaffected by angiotensin AT1 receptor antagonism, indicating that low K+ intake activates the distal nephron by an angiotensin-independent mode of action. High K+ intake was associated with elevated plasma aldosterone concentrations and an upregulation of the epithelial sodium channel (ENaC) and its activating kinase Sgk1. Surprisingly, high K+ intake increased blood pressure even during ENaC or mineralocorticoid receptor antagonism, suggesting the contribution of aldosterone-independent mechanisms. These findings show that in a Na+ replete state, changes in K+ intake induce specific molecular and functional adaptations in the distal nephron that cause a functional coupling of renal K+ and Na+ handling, resulting in Na+ retention and high blood pressure when K+ intake is either restricted or excessively increased.

  4. Eletrencefalograma na síndrome parkinsoniana

    Directory of Open Access Journals (Sweden)

    José Geraldo Camargo Lima

    1973-09-01

    Full Text Available Foram estudados os eletrencefalogramas de 50 pacientes parkinsonianos livres de qualquer antecedente convulsivo, sendo registrados traçados anormais em 40% dos casos. A incidência de traçados anormais foi maior na síndrome parkinsoniana bilateral do que na unilateral (52% e 25%, respectivamente. Entre as anormalidades assinaladas foram as paroxísticas as mais freqüentes (65% dos casos, caracterizando-se predominantemente por surtos de ondas teta. O registro de anormalidades paroxísticas do tipo irritativo encontrado em três casos é salientado. Alterações da atividade de base foram assinaladas em 35% dos pacientes. A idade dos pacientes não parece ter tido importante papel na gênese das anormalidades eletrencefalográficas.

  5. Hidroginástica na terceira idade

    OpenAIRE

    Karla Campos de Paula; Débora Campos de Paula

    1998-01-01

    O processo de envelhecimento no indivíduo saudável está relacionado com inúmeras alterações psicológicas e físicas que interferem na área motora, concorrendo para a inatividade e contribuindo para o aparecimento e agravamento de determinadas doenças, além de influenciar negativamente a realização das atividades de vida diária. Portanto, a prática de atividade física é fundamental para o idoso, não só na prevenção de doenças como na reabilitação de suas habilidades motoras, promovendo um estil...

  6. UTJECAJ GMO NA EKOLOŠKU POLJOPRIVREDU

    OpenAIRE

    Fagan, John

    2008-01-01

    Gotovo svi znanstvenici se slažu da su danas uobičajene metode za ugradnju novog gena u genom biljke putem genetičkog inženjerstva (genetičke modifikacije): (1) neprecizne i slučajne, (2) pa je njihov utjecaj na biološke funkcije biljke nepredvidiv, (3) a neželjeni učinci GMO na zdravlje konzumenta i na okoliš mogući. Korištenje GMO u ekološkoj poljoprivredi je zabranjeno, stoga potrošač vjeruje da oznaka “ekološki” zakonski štiti od prisustva GMO u hrani. Međutim, povećano korištenje GMO u k...

  7. Estatuto do Audiovisual de TV na Internet

    Directory of Open Access Journals (Sweden)

    KILPP, Suzana

    2012-08-01

    Full Text Available O artigo é um relato parcial da pesquisa Audiovisualidades Digitais que realizamos de 2009 a 2011. Fazemos uma rápida incursão em alguns sites de emissoras de TV na Internet para autenticar os tipos de postagens de vídeo (e suas características imagéticas na circunvizinhança de outras postagens que participam do design de interface das homes e das watchpages dos mesmos, e assim tecer considerações preliminares sobre o estatuto do audiovisual de TV na Internet. Tais considerações são tensionadas por conceitos de Benjamin, Bergson, Bolter e Grusin, Derrida, Flusser, Kilpp, Manovich, e McLuhan, e inscrevem-se numa ecologia audiovisual que vimos perseguindo em nossas pesquisas.

  8. Recent results from MoNA-LISA

    Science.gov (United States)

    Spyrou, Artemisia

    2012-03-01

    Studies of the nuclear properties of nuclei close and even beyond the limits of stability have revealed exotic modes of decay and new structural characteristics. The MoNA-LISA array is used at the National Superconducting Cyclotron Laboratory at Michigan State University to study nuclei along the neutron dripline. In a typical experiment, a radioactive beam is employed to produce the neutron-unbound state of interest. This state/resonance immediately decay into a neutron, which is detected by MoNA-LISA and a remaining charged nucleus detected by the sweeper magnet detector suite. In this talk, new exciting findings from recent MoNA-LISA experiments will be presented. These include the first observation of a dineutron decay from ^16Be, the exploration of the ``south shore'' of the Island of Inversion and the first evidence of the decay of the troubling nucleus ^26O.

  9. Random integral equations on time scales

    Directory of Open Access Journals (Sweden)

    Vasile Lupulescu

    2013-01-01

    Full Text Available In this paper, we present the existence and uniqueness of random solution of a random integral equation of Volterra type on time scales. We also study the asymptotic properties of the unique random solution.

  10. Targeting voltage gated sodium channels NaV1.7, Na V1.8, and Na V1.9 for treatment of pathological cough.

    Science.gov (United States)

    Muroi, Yukiko; Undem, Bradley J

    2014-02-01

    Recent advances in our understanding of voltage-gated sodium channels (NaVs) lead to the rational hypothesis that drugs capable of selective blockade of NaV subtypes may be a safe and effective strategy for the treatment of unwanted cough. Among the nine NaV subtypes (NaV1.1-NaV1.9), the afferent nerves involved in initiating cough, in common with nociceptive neurons in the somatosensory system, express mainly NaV1.7, NaV1.8, and NaV1.9. Although knowledge about the effect of selectively blocking these channels on the cough reflex is limited, their biophysical properties indicate that each may contribute to the hypertussive and allotussive state that typifies subacute and chronic nonproductive cough.

  11. Phase Transitions on Random Lattices: How Random is Topological Disorder?

    Science.gov (United States)

    Barghathi, Hatem; Vojta, Thomas

    2015-03-01

    We study the effects of topological (connectivity) disorder on phase transitions. We identify a broad class of random lattices whose disorder fluctuations decay much faster with increasing length scale than those of generic random systems, yielding a wandering exponent of ω = (d - 1) / (2 d) in d dimensions. The stability of clean critical points is thus governed by the criterion (d + 1) ν > 2 rather than the usual Harris criterion dν > 2 , making topological disorder less relevant than generic randomness. The Imry-Ma criterion is also modified, allowing first-order transitions to survive in all dimensions d > 1 . These results explain a host of puzzling violations of the original criteria for equilibrium and nonequilibrium phase transitions on random lattices. We discuss applications, and we illustrate our theory by computer simulations of random Voronoi and other lattices. This work was supported by the NSF under Grant Nos. DMR-1205803 and PHYS-1066293. We acknowledge the hospitality of the Aspen Center for Physics.

  12. MEDGENERACIJSKI PRENOS ZNANJA NA DELOVNEM MESTU

    OpenAIRE

    Movern, Tina

    2015-01-01

    Prenos znanja med ljudmi igra ključno vlogo pri razvoju ter napredku človeštva. Nekaterih najbolj kompleksnih znanj kot so jeziki in kulturne norme, so lahko naučena oziroma priučena od drugih ljudi, ti pa so jih pridobili od prejšnjih generacij. Kot glavno gonilno silo razvoja neke organizacije bi prav lahko vzeli količino, kvaliteto in možnost upravljanja prenosa znanj v sami organizaciji, kar je tudi glavni predmet naše raziskave. Diplomska naloga je razdeljena na teoretični in empiri...

  13. Recent results and prospects from NA62

    Directory of Open Access Journals (Sweden)

    Bizzeti Andrea

    2016-01-01

    K+ → π+ vv̄ is a theoretically very clean decay where indirect effects of new physics may be detectable. The NA62 apparatus has been significantly upgraded between 2008 and 2014 in order to measure the branching ratio of this decay with 10% precision. The NA62 experiment took data with the new setup in pilot runs in 2014 and 2015, reaching the design beam intensity. Results of first data quality studies in view of the 2016-2017 physics runs are presented.

  14. ŽENSKE NA PODEŽELJU

    OpenAIRE

    Planko, Polonca

    2014-01-01

    V diplomskem delu so obravnavane razlike in podobnosti v vsakodnevnem delovanju kmečkih in nekmečkih žensk. Pri tem sem se osredotočila na vrsto dnevnih opravil, koliko časa porabijo zanje in kje jih opravljajo. Med vsakodnevna opravila sem uvrstila delovne, oskrbovalne, rekreacijske, izobraževalne ter komunikacijske navade. S tem sem spoznala akcijski prostor anketiranih žensk. Za raziskovalni vzorec sem izbrala deset žensk, ki živijo na podeželju, pet kmečkih in pet nekmečkih žensk. Vse žen...

  15. UTJECAJ KALCIZACIJE NA PRINOS SIJENA LUCERNE

    OpenAIRE

    Svetislav POPOVIĆ; Marijana TUCAK; Tihomir ČUPIĆ; Kovačević, Vlado

    2009-01-01

    Lucerna je najznačajnija krmna leguminoza na oranicama u Republici Hrvatskoj (zasijana je na oko 45000 ha – stanje 2003.). U jesen 2004. godine postavljen je poljski pokus s četiri doze (0, 10, 20, 30 i 40 tha-1) vapna (Agrovapno MgO: 56% CaO and 40% MgO). Pokus je postavljen po shemi slučajnoga bloknoga rasporeda u četiri ponavljanja. U proljeće 2005. godine zasijana je lucerna (Osječanka 88, sorta Poljoprivrednog Instituta Osijek). Ostvarena su po četiri otkosa u svakoj godini istraživanja....

  16. ANALIZA IZGUB NA OSLABLJENEM PRENAPETOSTNEM ODVODNIKU

    OpenAIRE

    Ajdnik, Miran

    2011-01-01

    Diplomska naloga obravnava problematiko izgub električne energije na oslabljenem prenapetostnem odvodniku na transformatorski postaji Kot-Makej (0,95/0,4 kV) in neozemljenem izvoru. Omenjena transformatorska postaja se napaja iz razdelilne transformatorske postaje Ravne (RTP RAVNE) preko 20 kV daljnovoda Mežica in transformatorske postaje Kot (20/0,95/0,4 kV). Rešitev je predstavljena s programskim orodjem MATLAB/Simulink iz knjižnice PowerSystem, s katerim je izvedena simulacija pri oslablje...

  17. Status for 2017, CERN NA63

    CERN Document Server

    Uggerhoej, UI

    2017-01-01

    In the NA63 experiment of May-June 2017 the purpose was to look for the effect of classical radiation reaction as described in \\cite{DiPiazza20171} but for 50 GeV positrons aligned to the (110) plane of silicon crystals of varying thicknesses in the range 1-6 mm. The data which was taken during the run shows promising results, but the final verdict awaits accurate calculations of the theoretically expected spectra, and a final analysis. For the 2016 results on quantum radiation reaction obtained by CERN NA63, we have submitted a manuscript, which is presently under refereeing \\cite{Wist17}.

  18. AVTOMATIZIRANE TRGOVALNE STRATEGIJE NA FOREX TRGU

    OpenAIRE

    Kresnik, Jan

    2014-01-01

    Trgovanja brez točno določene strategije skoraj ni mogoče objektivno oceniti. Vsak trgovalec ima svojo predstavo o trgu in lahko iz enakih informacij naredi drugačne zaključke kot nek drug trgovalec. Zaradi tega je danes vse bolj v veljavi trgovanje na osnovi algoritmov, ki vedno sprejmejo enako odločitev, in sicer glede na parametre, ki jih trgovalec želi vstaviti v strategijo. Prav tako lahko rezultate ene strategije primerjamo z rezultati druge strategije, saj vemo, da je končni rezultat p...

  19. Sociokulturni aspekti amaterske pornografije na internetu

    OpenAIRE

    Filipović, Branislav

    2016-01-01

    Savremeni diskurs amaterske pornografije na internetu izmiče tradicionalnim interpretativnim shemama koje i “kućne” seks snimke povezuju sa delovanjem seks-industrije.Predmet istraživanja su internet stranice na kojima su dostupni pornografski sadržaji amaterske produkcije. U centru naučne pažnje rada nalaze se pornografski materijali i prakse “običnih ljudi” u virtuelnom domenu kiberprostora.Istraživanje polazi od stanovišta da je amaterska pornografija specifi...

  20. ANALIZA KONKURENCE NA TRGU KINEMATOGRAFOV V SLOVENIJI

    OpenAIRE

    Lipovčić, Vesna

    2009-01-01

    Trg kinematografov v Sloveniji doživlja zadnjih nekaj let pomembne spremembe. Gradnja multipleksov je pomenila velik prelom v navadah obiskovanja kinematografov, drugačen način preživljanja prostega časa in višjo vrednost storitve za obiskovalce. Razvoj tehnologije je povzročil nastanek posredne konkurence, ki nudi danes možnost ogleda filmov preko interneta, avdiovizualnih medijev in televizije. Na tako konkurenčnem trgu imajo možnost preživeti samo tisti, ki dovolj dobro poznajo trg in svoj...

  1. ARTE E TRANSGRESSÃO NA MODERNIDADE

    OpenAIRE

    Cascelli Farinasso, Gabriela

    2014-01-01

    O presente artigo busca explorar a arte como ferramenta para mudanças sociais na modernidade relacionando-a com os conceitos apresentados por Nicolas Bourriaud em seu livro Estética Relacional. A Street Art é apresentada como recorte dentre os movimentos artísticos, ressaltando-se sua importância e suas características do ponto de vista espacial e temporal e na criação de “lugares de pausa” no meio urbano, que levam o observador a refletir sobre a obra e o desviam do seu percurso. A transgres...

  2. A Imagem como Ruína

    Directory of Open Access Journals (Sweden)

    Míriam Volpe

    2001-12-01

    Full Text Available O dialogismo ente o filme Citizen Kane, de Orson Welles, e o poema “Kubla Khan”, de S.T. Coleridgé, é analisado, sendo evidenciados não só o tema em comum – o mito do Paraíso perdido – como também a similariedade na organização do disurso na justaposição das images, como fragmentos da memória a serem preservados.

  3. Europlanet-2020 NA1 Exchange Program

    Science.gov (United States)

    Genzer, M.; Szego, K.; Haukka, H.; Harri, A.-M.

    2017-09-01

    The task of Exchange Program of NA1 is to support the activities of EPN2020 with experts and scientific exchange whenever it is needed. Short visits (up to 1 week) with the goal of improving infrastructure facilities and services offered to the scientific community are supported from this task. Since the start of the EPN2020 in September 2015 we have received and approved 14 applications for exchange program travel. More general and specifically targeted calls are planned for the future. The calls are announced on Europlanet-2020 NA1 web site.

  4. Alterações cognitivas na esquizofrenia

    OpenAIRE

    THEIL, Ruth Bonow

    2003-01-01

    Este estudo é uma revisão da literatura sobre o comprometimento cognitivo na esquizofrenia. Objetivou-se a análise da natureza e do padrão desse comprometimento, o estabelecimento de associações entre as variáveis clínicas e o desempenho neuropsicológico, e a determinação das correlações entre os déficits cognitivos na esquizofrenia e seus substratos neurais subjacentes. Foram inicialmente revistos os conceitos de esquizofrenia e sua evolução histórica, aspectos clínicos, cl...

  5. Vzroki za nastanek napak na robovih obdelovancev

    OpenAIRE

    Rakovec, Majda

    2014-01-01

    V proizvodnji nastajajo napake različnih vrst in imajo številne vzroke. V podjetju Alples d.d. je velik problem kakovosti robov samih obdelovancev, po ugotovitvah in izračunih je neskladnosti v zvezi z robovi kar 20,8 %. Vzroke za odstopanje iščemo v sami proizvodnji, kar pa ni vedno upravičeno. Na osnovi analize obstoječega stanja kakovosti smo ugotovili, da je vzroke za odstopanja treba iskati tudi v sami organizaciji proizvodnje. Seveda pa so lahko vzroki tudi drugje, na primer: obraba oro...

  6. A morte da culpa na responsabilidade contratual

    OpenAIRE

    Marcos Jorge Catalan

    2011-01-01

    Esta pesquisa tem, por hipótese, a morte da culpa na responsabilidade contratual e, por objeto, aferir se o aludido elemento subjetivo pode (ou não) ser suprimido da arquitetura jurídica da responsabilidade contratual. Vale resgatar que, se é certo não sem vozes em sentido oposto que, em muitos momentos, o direito contratual não reservou papel algum à culpa, em outros tantos instantes, na visão da doutrina majoritária, ela continua a brilhar como em seus momentos de maior esplendor. A tese ...

  7. O problema do conhecimento verdadeiro na epidemiologia

    Directory of Open Access Journals (Sweden)

    Ayres José Ricardo de Carvalho Mesquita

    1992-01-01

    Full Text Available São examinadas as bases filosóficas da validação do conhecimento científico, com o intuito de estabelecer uma visão crítica a respeito da adoção das proposições de Popper na epidemiologia. Ressalta-se o caráter conservador que resulta das limitações técnicas implicadas na sua adoção, não obstante o evidente aumento da racionalidade e da criatividade heurística que propicia.

  8. Analysis of Naïve Bayes Algorithm for Email Spam Filtering across Multiple Datasets

    Science.gov (United States)

    Fitriah Rusland, Nurul; Wahid, Norfaradilla; Kasim, Shahreen; Hafit, Hanayanti

    2017-08-01

    E-mail spam continues to become a problem on the Internet. Spammed e-mail may contain many copies of the same message, commercial advertisement or other irrelevant posts like pornographic content. In previous research, different filtering techniques are used to detect these e-mails such as using Random Forest, Naïve Bayesian, Support Vector Machine (SVM) and Neutral Network. In this research, we test Naïve Bayes algorithm for e-mail spam filtering on two datasets and test its performance, i.e., Spam Data and SPAMBASE datasets [8]. The performance of the datasets is evaluated based on their accuracy, recall, precision and F-measure. Our research use WEKA tool for the evaluation of Naïve Bayes algorithm for e-mail spam filtering on both datasets. The result shows that the type of email and the number of instances of the dataset has an influence towards the performance of Naïve Bayes.

  9. Mondrian Forests: Efficient Online Random Forests

    OpenAIRE

    Lakshminarayanan, Balaji; Roy, Daniel M.; Teh, Yee Whye

    2014-01-01

    Ensembles of randomized decision trees, usually referred to as random forests, are widely used for classification and regression tasks in machine learning and statistics. Random forests achieve competitive predictive performance and are computationally efficient to train and test, making them excellent candidates for real-world prediction tasks. The most popular random forest variants (such as Breiman's random forest and extremely randomized trees) operate on batches of training data. Online ...

  10. Wave propagation and scattering in random media

    CERN Document Server

    Ishimaru, Akira

    1978-01-01

    Wave Propagation and Scattering in Random Media, Volume 2, presents the fundamental formulations of wave propagation and scattering in random media in a unified and systematic manner. The topics covered in this book may be grouped into three categories: waves in random scatterers, waves in random continua, and rough surface scattering. Random scatterers are random distributions of many particles. Examples are rain, fog, smog, hail, ocean particles, red blood cells, polymers, and other particles in a state of Brownian motion. Random continua are the media whose characteristics vary randomly an

  11. Random operator equations in mathematical physics. I

    Science.gov (United States)

    Adomian, G.

    1970-01-01

    Stochastic differential equations objectives, limitations and restrictive assumptions in physical problems, discussing electromagnetic wave propagation in random continuum or random dAlembertian operator

  12. The parabolic Anderson model random walk in random potential

    CERN Document Server

    König, Wolfgang

    2016-01-01

    This is a comprehensive survey on the research on the parabolic Anderson model – the heat equation with random potential or the random walk in random potential – of the years 1990 – 2015. The investigation of this model requires a combination of tools from probability (large deviations, extreme-value theory, e.g.) and analysis (spectral theory for the Laplace operator with potential, variational analysis, e.g.). We explain the background, the applications, the questions and the connections with other models and formulate the most relevant results on the long-time behavior of the solution, like quenched and annealed asymptotics for the total mass, intermittency, confinement and concentration properties and mass flow. Furthermore, we explain the most successful proof methods and give a list of open research problems. Proofs are not detailed, but concisely outlined and commented; the formulations of some theorems are slightly simplified for better comprehension.

  13. Localization transition of biased random walks on random networks.

    Science.gov (United States)

    Sood, Vishal; Grassberger, Peter

    2007-08-31

    We study random walks on large random graphs that are biased towards a randomly chosen but fixed target node. We show that a critical bias strength bc exists such that most walks find the target within a finite time when b > bc. For b infinity before hitting the target. The phase transition at b=bc is a critical point in the sense that quantities such as the return probability P(t) show power laws, but finite-size behavior is complex and does not obey the usual finite-size scaling ansatz. By extending rigorous results for biased walks on Galton-Watson trees, we give the exact analytical value for bc and verify it by large scale simulations.

  14. Evaluation of NaCl Salinity Stress Using Three Different Laboratory Methods

    Directory of Open Access Journals (Sweden)

    S Laleh

    2012-02-01

    Full Text Available To investigate the effects of different salinity levels of NaCl on germination of safflower (cv. Esfahan 24 seeds under three different incubation methods, a factorial experiment was carried out based on a complete randomize design with three replications. Salinity levels were 0, 5, 10, 15 and 20 dSm-1 (NaCl and incubation methods were sandwich method, and using petri dishes with open or closed doors. The results showed that among investigated traits, including germination percentage and rate, length, fresh and dry weight of root and shoot, salinity had the highest negative correlation with germination percentage. There was not a significant difference in germination percentage between 5 dSm-1 and control, but increasing salinity levels to 10, 15 and 20 dSm-1 led to 13, 23.50 and 39.74 % reduction in germination percentage, respectively, compared to control (P

  15. Advances in randomized parallel computing

    CERN Document Server

    Rajasekaran, Sanguthevar

    1999-01-01

    The technique of randomization has been employed to solve numerous prob­ lems of computing both sequentially and in parallel. Examples of randomized algorithms that are asymptotically better than their deterministic counterparts in solving various fundamental problems abound. Randomized algorithms have the advantages of simplicity and better performance both in theory and often in practice. This book is a collection of articles written by renowned experts in the area of randomized parallel computing. A brief introduction to randomized algorithms In the aflalysis of algorithms, at least three different measures of performance can be used: the best case, the worst case, and the average case. Often, the average case run time of an algorithm is much smaller than the worst case. 2 For instance, the worst case run time of Hoare's quicksort is O(n ), whereas its average case run time is only O( n log n). The average case analysis is conducted with an assumption on the input space. The assumption made to arrive at t...

  16. Utjecaj načina dodavanja spora Penicillium candidum na svojstva kozjeg sira "Blanka"

    OpenAIRE

    Škorput, Dubravko

    1991-01-01

    Pretpostavka da u postupku proizvodnje sira s plijesnima na površini način primjene spora utječe na sastav i svojstva sira provjerena je u pokusu postavljenom u industrijskim, uvjetima proizvodnje. Tri su skupine uzoraka kozjeg sira "Blanka" proizvedene u po deset dnevnih proizvodnji i za svaku je proizvodnju utrošeno po 2.000 litara miješanog kozjeg i kravljeg mlijeka (omjer I -.1). Vodena suspenzija spora Penicillium candidum dodavana je: a) u mlijeko prije dodavanja sirila, h) raspršivanje...

  17. TEHNIČNA ANALIZA IN NJENA UPORABA NA DELNIŠKIH IN VALUTNIH TRGIH

    OpenAIRE

    Grobelnik, Klemen

    2010-01-01

    Z razvojem informacijske tehnologije ter pojavom vedno več preprostih trgovalnih platform, ki jih ponujajo razne investicijske družbe ter banke, se vedno več posameznikov odloča za samostojno trgovanje, ki naj bi prineslo velike dobičke. Posamezniki se velikokrat premalo zavedajo tveganja, ki je s samostojnim vstopom na delniške, valutne trge prisotno. Vlagatelji potrebujejo za trgovanje na podlagi tehničnih dejavnikov ogromno teoretičnega znanja in predhodnih izkušenj, zato tehnična analiza ...

  18. Presoja notranjih kontrol pri obračunu davka na dodano vrednost na primeru "Podjetja x"

    OpenAIRE

    Majcen, Borut

    2016-01-01

    Poslovanje podjetja si je ob odsotnosti notranjih kontrol nemogoče predstavljati. Podjetja so podvržena raznim tveganjem, še posebej v današnjih razmerah globalnega poslovanja, ko se podjetja soočajo z vedno novimi izzivi, kar prinaša tudi nova tveganja. Najučinkovitejši ukrep za obvladovanje tveganj predstavlja vzpostavitev sistema notranjih kontrol. Obvladovanje tveganj pa ne poteka samo na ravni podjetja kot celote, ampak je prisotno na vseh področjih delovanja podjetja, torej tudi na p...

  19. Fitoterápicos na odontologia: estudo etnobotânico na cidade de Manaus

    OpenAIRE

    Evangelista,S. S.; Sampaio,F.C.; Parente,R.C.; Bandeira,M. F. C. L.

    2013-01-01

    O reconhecimento oficial da fitoterapia na odontologia no Brasil veio acompanhado de diversas lacunas na pesquisa científica e na utilização de plantas medicinais, especificamente para espécies vegetais com aplicação nas doenças da cavidade oral. O estado do Amazonas, especificamente a cidade de Manaus, não possui um diagnóstico da aplicabilidade de plantas medicinais nos serviços de atenção Odontológica. Esse estudo propôs realizar um estudo do tipo quali-quantitativo, descritivo e explorató...

  20. Study of deconfinement in NA50

    Indian Academy of Sciences (India)

    Corrado Cicalo

    The anomalous J/ψ pattern suppression observed in NA50 experiment is a clear evidence of the transition to a deconfined state of matter. Acknowledgements. This work was partially supported by Fundaç˜ao para a Ciência e a Tecnologia, by INTAS grant 96-0231 and by the Russian Foundation for Fundamental Research, ...

  1. NA48: Wiring up for Change

    CERN Multimedia

    2001-01-01

    The NA48 Collaboration is rebuilding its drift chambers ready for the experiment to start up again this coming July. An intricate task involving the soldering of over 24,000 wires! The future of the NA48 experiment is coming right down to the wire, that is, the wires which the Collaboration is installing in the clean room of Hall 887 on the Prévessin site. Six days a week, technicians are working in shifts to rebuild the experiment's drift chambers. The original chambers were damaged when a section of a vacuum tube imploded at the end of 1999. A year ago, CERN gave the green light for this essential part of the spectrometer to be rebuilt, so the NA48 experiment, which studies CP violation (see box), still has a bright future ahead of it. Three years of data-taking ahead The NA48 experiment aims to penetrate the secrets of CP (Charge Parity) violation. Charge and parity are two parameters which distinguish a particle from an antiparticle. In other words, an electron possesses a negative electric ...

  2. NA62 experiment at CERN SPS

    CERN Document Server

    INSPIRE-00169974

    2014-01-01

    The NA62 experiment at SPS is a continuation of the long standing CERN kaon physics program. The high statistics and the unprecedent precision allow to probe the Standard Model and test the description of the strong interactions at low energy. The final results on the the lepton universality test by measuring the ratio $R_K = \\Gamma(K^{+}\\to e^{+}\

  3. Mwaka Kogwa Na Changamoto Zake | Mohamed | Kiswahili

    African Journals Online (AJOL)

    Kila jamii ina jadi yake ambayo inaweza kutumika katika kuitofautisha jamii hiyo na jamii zingine, za karibu au za mbali. Makunduchi ni miongoni mwa maeneo yanamozungumzwa lahaja za Kiswahili. Lahaja inayozungumzwa katika eneo hili inaitwa Kimakunduchi. Miongoni mwa matukio muhimu ya kijadi yanayofanyika ...

  4. Stark broadening parameter tables for Na X

    Directory of Open Access Journals (Sweden)

    Dimitrijević M.S.

    1998-01-01

    Full Text Available Using a semiclassical approach, we have calculated electron−, proton−, and He III−impact line widths and shifts for 57 Na X multiplets as a function of temperature (200 000 K - 5 000 000 K and perturber density (1017cm−3 - 1024cm−3.

  5. NA49: lead-lead collision

    CERN Multimedia

    1996-01-01

    This is an image of an actual lead ion collision taken from tracking detectors on the NA49 experiment, part of the heavy ion project at CERN. These collisions produce a very complicated array of hadrons as the heavy ions break up. It is hoped that one of these collisions will eventually create a new state of matter known as quark-gluon plasma.

  6. Habitus professoral na sala de aula virtual

    Directory of Open Access Journals (Sweden)

    Alexandre Marinho Pimenta

    2014-09-01

    Full Text Available Entendendo que a indiferença na ação pedagógica contribui para a reprodução das desigualdades no sistema de ensino, o presente artigo busca captar, a partir de entrevistas semiestruturadas, traços do habitus de professores supervisores de disciplinas do curso de Licenciatura em Pedagogia na modalidade a distância na Universidade de Brasília - UnB no âmbito do Sistema Universidade Aberta do Brasil - UAB. As orientações metodológicas de Bourdieu (2007 foram um dos elementos orientadores na análise das entrevistas, considerando ainda o uso heurístico do conceito de habitus. Conclui-se que o habitus professoral envolve esforços voluntários em busca de uma ação pedagógica diferenciada. No entanto, ele é ambíguo e condescendente frente aos limites do modelo de EaD no âmbito da UAB. Ao fim, os dados analisados permitem fornecer elementos para reorientação político-pedagógica que vise a um novo modelo de EaD nacional.

  7. Pijn tijdens of na de wortelkanaalbehandeling

    NARCIS (Netherlands)

    Wesselink, P.R.

    2012-01-01

    Een wortelkanaalbehandeling kan pijn veroorzaken tijdens en/of na de behandeling. Tijdens de behandeling moet dan onderscheid worden gemaakt tussen pijn bij een pulpitis en pijn bij een necrotische pulpa. In beide gevallen kan die pijn effectief worden bestreden, afhankelijk van de toestand waarin

  8. Concentratie gewasbeschermingsmiddelen na verhitting dompelbad bloembollen

    NARCIS (Netherlands)

    Bulle, A.A.E.; Lans, van der A.M.; Aanholt, van J.T.M.

    2014-01-01

    De meest gebruikte methode van ontsmetting van bloembollen en –knollen is een dompeling in een mix van fungiciden. In het proces van bolontsmetting worden partijen bollen na elkaar ontsmet in hetzelfde dompelbad. Met een partij bollen kan een dompelbad behoorlijk vervuild raken met bijvoorbeeld

  9. DIE EINDE VAN SENDING Fases in die Sendingbedryf

    African Journals Online (AJOL)

    ontwikkeling vir die verskeie rasse woonagtig in Suid-Afrika, beter bekend as die beleid van apartheid. (Inderdaad was hierdie gewraakte gedagtes nogal 'n integrale deel van die Kerk se Sendingbeleid soos wat dit in die vroeë 20ste eeu ontwikkel is.) Maar terwyl hierdie kritiek in feitlik alle opsigte toegegee kan word, is dit ...

  10. Learning between projects: More than sending messages in bottles

    OpenAIRE

    Hartmann, Andreas; Dorée, André

    2015-01-01

    Although learning from projects has gained much importance in research and practice, progress in understanding and improving inter-project learning appears to be slight. We argue that the adoption of a sender/receiver approach limits the learning effectiveness in project-based organisations. Drawing upon the notion of learning as a social activity embedded in an organisational context, we develop the argument that learning from projects takes place within projects rooted in the historical, or...

  11. The Readiness is All: Here Am I. Send Me.

    Directory of Open Access Journals (Sweden)

    Janet Tipton Hindman

    2016-06-01

    Full Text Available The article uses contextual biography to examine the psychological and existential dimensions of “an internal environment that interacts with the other contexts in which the [author] evolves (Vidal, F., 2003, p. 73. Through a network of enterprises (Gruber, 1980 as a key aspect of that internal environment, this contextual autobiography conceptualizes a slice of the author’s life through the integration of particular literary and life contexts and her position within these background experiences. By using a unique and creative narrative of personal experiences, the author posits the universal or ontological problem of understanding the “all” of readiness for one of Shakespeare’s central characters with the juxtaposition of her own life as undertaken through the literary contexts examined. A catastrophic spinal injury coupled with the loss of her beloved father serve as prime catalysts for extreme life changes for the author creating questions of self-doubt and self-awareness, and whether the readiness for her was indeed, all. The article purposively adds to our understanding of how the internal environment and network of enterprises within an individual’s life experiences juxtaposed with literary contexts may profoundly inspire others to live unique lives of action and readiness.  Findings of the study present the participant’s joyful journey of discovery and personal renewal with the most important lesson learned being that education is the ticket to a life of freedom and personal success.

  12. Who Sends the Email? Using Electronic Surveys in Violence Research

    Directory of Open Access Journals (Sweden)

    Melissa A Sutherland

    2013-08-01

    Full Text Available Introduction: Students aged 16–24 years are at greatest risk for interpersonal violence and the resulting short and long-term health consequences. Electronic survey methodology is well suited for research related to interpersonal violence. Yet methodological questions remain about best practices in using electronic surveys. While researchers often indicate that potential participants receive multiple emails as reminders to complete the survey, little mention is made of the sender of the recruitment email. The purpose of this analysis is to describe the response rates from three violence-focused research studies when the recruitment emails are sent from a campus office, researcher or survey sampling firm. Methods: Three violence-focused studies were conducted about interpersonal violence among college students in the United States. Seven universities and a survey sampling firm were used to recruit potential participants to complete an electronic survey. The sender of the recruitment emails varied within and across the each of the studies depending on institutional review boards and university protocols.Results: An overall response rate of 30% was noted for the 3 studies. Universities in which researcher initiated recruitment emails were used had higher response rates compared to universities where campus officials sent the recruitment emails. Researchers found lower response rates to electronic surveys at Historically Black Colleges or Universities and that other methods were needed to improve response rates.Conclusion: The sender of recruitment emails for electronic surveys may be an important factor in response rates for violence-focused research. For researchers identification of best practices for survey methodology is needed to promote accurate disclosure and increase response rates. [West J Emerg Med. 2013;14(4:363–369.

  13. Sending the Right Signals | Center for Cancer Research

    Science.gov (United States)

    Diffuse large B-cell lymphomas (DLBCL), the most common type of non-Hodgkin’s lymphoma, causes about 10,000 deaths every year in the United States, even though about half of all patients are cured with current regimens. There are different subtypes of DLBCL that vary biologically and have significantly different rates of patient survival following chemotherapy, with the activated B cell-like (ABC) subtype being the least responsive to current therapies. So Louis M. Staudt M.D., Ph.D., Head of the Molecular Biology of Lymphoid Malignancies Section at CCR, and his team set out to find why patients with this subtype have such unfavorable outcomes and how treatment of this disease can be improved.

  14. Sending Signals Into Space: Is it Really a Bad Idea?

    Science.gov (United States)

    Shostak, S.

    We dispute the proposed policy of restricting certain categories of transmissions towards the sky, made in the interest of reducing danger to our planet from unknown beings. Those who favor such restrictions argue that by minimizing signals, or subjecting such transmissions to review, we would also lessen the possibility of a hostile response. However, we demonstrate that any putative extraterrestrials who are in possession of technology that would allow them to threaten our world, will also be able to detect the unintentional leakage signals that humans have been pouring into space since the Second World War, thus vitiating the effectiveness of the proposed restrictions. Furthermore, international consultation about transmission content ­ suggested as a defense against interstellar offense ­ is an uncertain policy at best. In addition, restrictions on strong signals would be an unacceptable, and unending, brake on human technical development.

  15. Where should I send it? Optimizing the submission decision process.

    Science.gov (United States)

    Salinas, Santiago; Munch, Stephan B

    2015-01-01

    How do scientists decide where to submit manuscripts? Many factors influence this decision, including prestige, acceptance probability, turnaround time, target audience, fit, and impact factor. Here, we present a framework for evaluating where to submit a manuscript based on the theory of Markov decision processes. We derive two models, one in which an author is trying to optimally maximize citations and another in which that goal is balanced by either minimizing the number of resubmissions or the total time in review. We parameterize the models with data on acceptance probability, submission-to-decision times, and impact factors for 61 ecology journals. We find that submission sequences beginning with Ecology Letters, Ecological Monographs, or PLOS ONE could be optimal depending on the importance given to time to acceptance or number of resubmissions. This analysis provides some guidance on where to submit a manuscript given the individual-specific values assigned to these disparate objectives.

  16. Where should I send it? Optimizing the submission decision process.

    Directory of Open Access Journals (Sweden)

    Santiago Salinas

    Full Text Available How do scientists decide where to submit manuscripts? Many factors influence this decision, including prestige, acceptance probability, turnaround time, target audience, fit, and impact factor. Here, we present a framework for evaluating where to submit a manuscript based on the theory of Markov decision processes. We derive two models, one in which an author is trying to optimally maximize citations and another in which that goal is balanced by either minimizing the number of resubmissions or the total time in review. We parameterize the models with data on acceptance probability, submission-to-decision times, and impact factors for 61 ecology journals. We find that submission sequences beginning with Ecology Letters, Ecological Monographs, or PLOS ONE could be optimal depending on the importance given to time to acceptance or number of resubmissions. This analysis provides some guidance on where to submit a manuscript given the individual-specific values assigned to these disparate objectives.

  17. Where Should I Send It? Optimizing the Submission Decision Process

    OpenAIRE

    Salinas, Santiago; Munch, Stephan B.

    2015-01-01

    How do scientists decide where to submit manuscripts? Many factors influence this decision, including prestige, acceptance probability, turnaround time, target audience, fit, and impact factor. Here, we present a framework for evaluating where to submit a manuscript based on the theory of Markov decision processes. We derive two models, one in which an author is trying to optimally maximize citations and another in which that goal is balanced by either minimizing the number of resubmissions o...

  18. Possible euro delay sends tremor throuhg Latvian government

    Index Scriptorium Estoniae

    2005-01-01

    Euroopa Keskpanga presidendi Jean-Claude Trichet' sõnul võib uute riikide liitumine eurotsooniga ilma nende majandust enamarenenud riikidega kooskõlastamata kutsuda esile probleeme EL-i majanduses. Ajalehe Telegraf andmeil võib Brüssel Läti liitmise eurotsooni riikide sekka paari aasta võrra edasi lükata

  19. Migration Flows from the Perspective of Sending and Receiving Countries

    DEFF Research Database (Denmark)

    Pytlikova, Mariola

    There are two specific phenomena that have had a large influence on the development in international migration during the last decades. First, while labor migration flows were dominating in the past, refugee immigrants and family reunion migrants from less developed non-Western countries have been......, the former communist countries have become a relatively new and large source of immigration. In my PhD thesis I analyze the recent developments in international migration by using a rich dataset, which I collected myself by contacting national statistical offices. I use state-of-art econometric tools in my...... empirical analyses. The thesis consists of an introduction/summary and 4 main chapters, and one of them is written with two co-authors. Concerning the phenomenon of changing composition of the international migration, one chapter of the thesis analyzes the determinants and selectivity in international...

  20. Learning between projects: More than sending messages in bottles

    NARCIS (Netherlands)

    Hartmann, Andreas; Dorée, André

    2015-01-01

    Although learning from projects has gained much importance in research and practice, progress in understanding and improving inter-project learning appears to be slight. We argue that the adoption of a sender/receiver approach limits the learning effectiveness in project-based organisations. Drawing

  1. Die Gereformeerde Ekumeniese Sinode en Sending 1984 | van der ...

    African Journals Online (AJOL)

    The Reformed Ecumenical Synod and Mission 1984. The Afrikaner nation in South Africa is a minority in its own country. The normal strive to become and stay sovereign is blamed in the face of the world as building concentration camps! That is a lie. And if the world is not prepared to accept it as a lie we are sure that in this ...

  2. Sending policies in dynamic wireless mesh using network coding

    DEFF Research Database (Denmark)

    Pandi, Sreekrishna; Fitzek, Frank; Pihl, Jeppe

    2015-01-01

    This paper demonstrates the quick prototyping capabilities of the Python-Kodo library for network coding based performance evaluation and investigates the problem of data redundancy in a network coded wireless mesh with opportunistic overhearing. By means of several wireless meshed architectures...... simulated on the constructed test-bed, the advantage of network coding over state of the art routing schemes and the challenges of this new technology are shown. By providing maximum control of the network coding parameters and the simulation environment to the user, the test-bed facilitates quick...... construction of simulation setups on top of it. The paper highlights the problem of redundant transmission of data by the overhearing nodes in a wireless mesh and by means of three simple simulation setups that are built on top of the test-bed, the paper provides a brief insight into the selection...

  3. Send Student Interest Skyward!: Soaring Teaches Aeronautics Basics

    Science.gov (United States)

    Scarcella, Joe; Wallace, Art

    2011-01-01

    Gliders and sailplanes provide a great launching platform for teaching about technology and scientific principles. Soaring is technological innovation in action, using earth's natural resources for energy and endurance during flight. This article focuses on the basics of soaring, which educators can use to increase excitement and interest in the…

  4. Send Student Interest Skyward! Soaring Teaches Aeronautics Basics

    Science.gov (United States)

    Scarcella, Joe; Wallace, Art

    2011-01-01

    Gliders and sailplanes provide a great launching platform for teaching about technology and scientific principles. Soaring is technological innovation in action, using earth's natural resources for energy and endurance during flight. This article focuses on the basics of soaring, which educators can use to increase excitement and interest in the…

  5. ‘It Sends a Cold Shiver down My Spine’

    DEFF Research Database (Denmark)

    Pors, Justine Grønbæk

    2016-01-01

    This paper offers new theoretical and empirical understanding of interruptions to strategy implementation by drawing attention to their ghostly nature. The paper proposes a theoretical framework for thinking about the ghostly by combining Freud’s concept of the uncanny with theorizing in cultural...... breaks down and middle managers come into contact with the broader social and political stakes of their work....

  6. Sending the right message : forty years of BBC Radio News

    NARCIS (Netherlands)

    Luscombe-Serlie, J.C.

    2012-01-01

    Radio is, compared to television and newspapers, an under-researched area in media studies. This research has looked at BBC Radio News in the period 1966-2008; it is a case study into the views of 43 (former) writers of the BBC Radio Newsroom and BBC Radio One. Interviews were conducted with

  7. THE DETERMINATION OF SALINITY AND NUTRITION (NaH2PO4 PROFILE IN Nannochloropsis oculata CULTIVATION TO GAIN MAXIMUM LIPID

    Directory of Open Access Journals (Sweden)

    Elida Purba

    2012-11-01

    Full Text Available The determination of salinity and nutrition (NaH2PO4 profile in Nannochloropsis oculata cultivationto gain maximum lipid was investigated. The purpose of this research was to determine the optimumsalinity and nutrition (NaH2PO4 to gain maximum lipid in Nannochloropsis oculata. Phosphor canbe obtained by adding NaH2PO4 and a salinity enhancement can be applied by adding NaCl to theculture. This research was run by matching each variable of salinity (33, 34, 35, and 36 ppt to eachvariable of NaH2PO4 (5, 10 and 15 ppm randomly. The results show that the percentage of maximumlipid in Nannochloropsis oculata was obtained at 35 ppt and 5 ppm NaH2PO4 (37.68 %. Neverthelessthe maximum lipid percentage is low and it can be caused by some factors, such as the dryingtemperature for preparing the dry microalgae to extract, the cell disruption method and the extractionsolvent used. By seeing the results, salinity can affect the total lipid in Nannochloropsis oculata. Thegreater the salinity in culture the greater the lipid content in Nannochloropsis oculata. Otherwise adifferent response was obtained by adding NaH2PO4. If NaH2PO4 concentration is greater, the lipidcontained Nannochloropsis oculata will be lower Penentuan profilsalinitas dan nutrisi (NaH2PO4 pada pembiakan Nannochloropsis oculata untuk memperoleh lipidmaksimum diteliti. Tujuan penelitian ini adalah untuk menentukan salinitas dan nutrisi (NaH2PO4optimum untuk memperoleh lipid maksimum pada Nannochloropsis oculata. Fosfor dapat diperolehdengan menambahkan NaH2PO4 pada kultur dan peningkatan salinitas dapat dilakukan denganmenambahkan NaCl pada kultur. Penelitian ini dijalankan dengan mencocokkan setiap variabelsalinitas (33, 34, 35, dan 36 ppt dengan setiap variabel NaH2PO4 (5, 10 dan 15 ppm secara acak.Hasil menunjukkan bahwa persentase lipid maksimum pada Nannochloropsis oculata diperoleh padasalinitas 35 ppt dan 5 ppm NaH2PO4 (37,68 %. Walaupun demikian, persentase lipid maksimummasih

  8. Biossegurança na odontologia

    Directory of Open Access Journals (Sweden)

    André Luiz Dantas Bezerra

    2014-04-01

    Full Text Available Introdução: As atividades laborais, de modo geral, expõem os trabalhadores a riscos ocupacionais dos mais variados. Esses riscos incluem agentes físicos, químicos, ergonômicos, de acidentes e biológicos. O contato rotineiro com esses últimos deve ser motivo de reflexão e intervenção. Objetivo: Descrever os aspectos da biossegurança na odontologia. Métodos: Foi realizada uma revisão do estado da arte, adotando-se critérios para análise dos trabalhos mais diretamente relacionados à prática odontológica. A partir dos descritores controlados (DeCS "biossegurança" e "odontologia", procederam-se a busca na Literatura Latino-Americana e do Caribe em Ciências da Saúde, na Scientific Electronic Library Online, na National Library of Medicine e na Biblioteca Cochrane. Resultados: Com a associação entre os DeCS, chegou-se a 66 artigos, porém, após refinamento foram incluídos nesta revisão 12 artigos. Nos resultados foi evidenciado que a produção científica sobre biossegurança é vasta, bem como é ampla na odontologia, contudo, quando da concentração de trabalhos contempladores da associação dos termos biossegurança e odontologia, a quantidade de estudos diminui consideravelmente. Não obstante, as pesquisas foram, em sua maioria, desenvolvidas por estudiosos nacionais, da região nordeste e evidenciaram que o conhecimento e a adoção de medidas de segurança biológica na área ainda são insuficientes para garantir a proteção da equipe e dos pacientes qualitativamente. Conclusão: Sugere-se que as normas de precaução padrão sejam seguidas rigidamente e que ações de educação sejam promovidas entre os profissionais.

  9. Acetylene diffusion in Na-Y zeolite

    Indian Academy of Sciences (India)

    elastic neu- tron scattering (QENS) measurements at temperatures of 300, 325 and 350 K is reported. A model in which the acetylene molecules undergo random-walk diffusion characterized by a Gaussian distribution of jump lengths inside zeolite ...

  10. Triangulation in Random Refractive Distortions.

    Science.gov (United States)

    Alterman, Marina; Schechner, Yoav Y; Swirski, Yohay

    2017-03-01

    Random refraction occurs in turbulence and through a wavy water-air interface. It creates distortion that changes in space, time and with viewpoint. Localizing objects in three dimensions (3D) despite this random distortion is important to some predators and also to submariners avoiding the salient use of periscopes. We take a multiview approach to this task. Refracted distortion statistics induce a probabilistic relation between any pixel location and a line of sight in space. Measurements of an object's random projection from multiple views and times lead to a likelihood function of the object's 3D location. The likelihood leads to estimates of the 3D location and its uncertainty. Furthermore, multiview images acquired simultaneously in a wide stereo baseline have uncorrelated distortions. This helps reduce the acquisition time needed for localization. The method is demonstrated in stereoscopic video sequences, both in a lab and a swimming pool.

  11. Black holes and random matrices

    Science.gov (United States)

    Cotler, Jordan S.; Gur-Ari, Guy; Hanada, Masanori; Polchinski, Joseph; Saad, Phil; Shenker, Stephen H.; Stanford, Douglas; Streicher, Alexandre; Tezuka, Masaki

    2017-05-01

    We argue that the late time behavior of horizon fluctuations in large anti-de Sitter (AdS) black holes is governed by the random matrix dynamics characteristic of quantum chaotic systems. Our main tool is the Sachdev-Ye-Kitaev (SYK) model, which we use as a simple model of a black hole. We use an analytically continued partition function | Z( β + it)|2 as well as correlation functions as diagnostics. Using numerical techniques we establish random matrix behavior at late times. We determine the early time behavior exactly in a double scaling limit, giving us a plausible estimate for the crossover time to random matrix behavior. We use these ideas to formulate a conjecture about general large AdS black holes, like those dual to 4D super-Yang-Mills theory, giving a provisional estimate of the crossover time. We make some preliminary comments about challenges to understanding the late time dynamics from a bulk point of view.

  12. Generating random networks and graphs

    CERN Document Server

    Coolen, Ton; Roberts, Ekaterina

    2017-01-01

    This book supports researchers who need to generate random networks, or who are interested in the theoretical study of random graphs. The coverage includes exponential random graphs (where the targeted probability of each network appearing in the ensemble is specified), growth algorithms (i.e. preferential attachment and the stub-joining configuration model), special constructions (e.g. geometric graphs and Watts Strogatz models) and graphs on structured spaces (e.g. multiplex networks). The presentation aims to be a complete starting point, including details of both theory and implementation, as well as discussions of the main strengths and weaknesses of each approach. It includes extensive references for readers wishing to go further. The material is carefully structured to be accessible to researchers from all disciplines while also containing rigorous mathematical analysis (largely based on the techniques of statistical mechanics) to support those wishing to further develop or implement the theory of rand...

  13. Free probability and random matrices

    CERN Document Server

    Mingo, James A

    2017-01-01

    This volume opens the world of free probability to a wide variety of readers. From its roots in the theory of operator algebras, free probability has intertwined with non-crossing partitions, random matrices, applications in wireless communications, representation theory of large groups, quantum groups, the invariant subspace problem, large deviations, subfactors, and beyond. This book puts a special emphasis on the relation of free probability to random matrices, but also touches upon the operator algebraic, combinatorial, and analytic aspects of the theory. The book serves as a combination textbook/research monograph, with self-contained chapters, exercises scattered throughout the text, and coverage of important ongoing progress of the theory. It will appeal to graduate students and all mathematicians interested in random matrices and free probability from the point of view of operator algebras, combinatorics, analytic functions, or applications in engineering and statistical physics.

  14. Cluster-randomized trial of a German leisure-based alcohol peer education measure

    OpenAIRE

    B?hler, Anneke; Thrul, Johannes; Str?ber, Evelin; Orth, Boris

    2015-01-01

    Because of scarce research, the effectiveness of substance abuse prevention in leisure settings remains unclear. In this study, we evaluated the effectiveness of a peer-led educational prevention measure with adolescent groups in unstructured leisure settings, which is a component of the complex German nationwide ?Na Toll!? campaign. Using a cluster-randomized two-group post-test-only design, we tested whether the measure influenced component-specific goals, namely risk and protective factors...

  15. Well-Loved Music Robustly Relieves Pain: A Randomized, Controlled Trial

    OpenAIRE

    Christine Hsieh; Jian Kong; Irving Kirsch; Robert R. Edwards; Karin B Jensen; Kaptchuk, Ted J.; Gollub, Randy L.

    2014-01-01

    Music has pain-relieving effects, but its mechanisms remain unclear. We sought to verify previously studied analgesic components and further elucidate the underpinnings of music analgesia. Using a well-characterized conditioning-enhanced placebo model, we examined whether boosting expectations would enhance or interfere with analgesia from strongly preferred music. A two-session experiment was performed with 48 healthy, pain experiment-naïve participants. In a first cohort, 36 were randomized...

  16. Cross over of recurrence networks to random graphs and random ...

    Indian Academy of Sciences (India)

    2017-01-27

    Jan 27, 2017 ... analysis based on net theoretic measures has developed into a major field, .... with the value of the scaling index γ falling between 2 and 3. To compute the network measures, we first construct an ensemble of synthetic networks, both random and ... higher k values are present to maintain the same γ. In both.

  17. Effect of NaCl salinity and soil waterlogging on growth characteristics of forage corn in greenhouse conditions

    OpenAIRE

    N. Najafi; E. Sarhangzadeh

    2012-01-01

    Salinity and waterlogging are two important abiotic stresses to plants growth and yield in the world. These two stresses can occur simultaneously and have additive effects on plants, including corn, growth. In a greenhouse experiment, the effects of NaCl salinity and waterlogging and their interactive effect on the growth characteristics of forage corn (Zea mays cv. single cross 704) were studied. A factorial experiment on the basis of completely randomized design with three replications was ...

  18. Bose condensation in (random traps

    Directory of Open Access Journals (Sweden)

    V.A. Zagrebnov

    2009-01-01

    Full Text Available We study a non-interacting (perfect Bose-gas in random external potentials (traps. It is shown that a generalized Bose-Einstein condensation in the random eigenstates manifests if and only if the same occurs in the one-particle kinetic-energy eigenstates, which corresponds to the generalized condensation of the free Bose-gas. Moreover, we prove that the amounts of both condensate densities are equal. This statement is relevant for justification of the Bogoliubov approximation} in the theory of disordered boson systems.

  19. Random organization and plastic depinning

    Energy Technology Data Exchange (ETDEWEB)

    Reichhardt, Charles [Los Alamos National Laboratory; Reichhardt, Cynthia [Los Alamos National Laboratory

    2008-01-01

    We provide evidence that the general phenomenon of plastic depinning can be described as an absorbing phase transition, and shows the same features as the random organization which was recently studied in periodically driven particle systems [L. Corte, Nature Phys. 4, 420 (2008)]. In the plastic flow system, the pinned regime corresponds to the absorbing state and the moving state corresponds to the fluctuating state. When an external force is suddenly applied, the system eventually organizes into one of these two states with a time scale that diverges as a power law at a nonequilibrium transition. We propose a simple experiment to test for this transition in systems with random disorder.

  20. Neutron transport in random media

    Energy Technology Data Exchange (ETDEWEB)

    Makai, M. [KFKI Atomic Energy Research Institute, Budapest (Hungary)

    1996-08-01

    The survey reviews the methods available in the literature which allow a discussion of corium recriticality after a severe accident and a characterization of the corium. It appears that to date no one has considered the eigenvalue problem, though for the source problem several approaches have been proposed. The mathematical formulation of a random medium may be approached in different ways. Based on the review of the literature, we can draw three basic conclusions. The problem of static, random perturbations has been solved. The static case is tractable by the Monte Carlo method. There is a specific time dependent case for which the average flux is given as a series expansion.

  1. Algebraic polynomials with random coefficients

    Directory of Open Access Journals (Sweden)

    K. Farahmand

    2002-01-01

    Full Text Available This paper provides an asymptotic value for the mathematical expected number of points of inflections of a random polynomial of the form a0(ω+a1(ω(n11/2x+a2(ω(n21/2x2+…an(ω(nn1/2xn when n is large. The coefficients {aj(w}j=0n, w∈Ω are assumed to be a sequence of independent normally distributed random variables with means zero and variance one, each defined on a fixed probability space (A,Ω,Pr. A special case of dependent coefficients is also studied.

  2. Composite continuous time random walks

    Science.gov (United States)

    Hilfer, Rudolf

    2017-12-01

    Random walks in composite continuous time are introduced. Composite time flow is the product of translational time flow and fractional time flow [see Chem. Phys. 84, 399 (2002)]. The continuum limit of composite continuous time random walks gives a diffusion equation where the infinitesimal generator of time flow is the sum of a first order and a fractional time derivative. The latter is specified as a generalized Riemann-Liouville derivative. Generalized and binomial Mittag-Leffler functions are found as the exact results for waiting time density and mean square displacement.

  3. Effects of non-uniform root zone salinity on water use, Na+ recirculation, and Na+ and H+ flux in cotton.

    Science.gov (United States)

    Kong, Xiangqiang; Luo, Zhen; Dong, Hezhong; Eneji, A Egrinya; Li, Weijiang

    2012-03-01

    A new split-root system was established through grafting to study cotton response to non-uniform salinity. Each root half was treated with either uniform (100/100 mM) or non-uniform NaCl concentrations (0/200 and 50/150 mM). In contrast to uniform control, non-uniform salinity treatment improved plant growth and water use, with more water absorbed from the non- and low salinity side. Non-uniform treatments decreased Na(+) concentrations in leaves. The [Na(+)] in the '0' side roots of the 0/200 treatment was significantly higher than that in either side of the 0/0 control, but greatly decreased when the '0' side phloem was girdled, suggesting that the increased [Na(+)] in the '0' side roots was possibly due to transportation of foliar Na(+) to roots through phloem. Plants under non-uniform salinity extruded more Na(+) from the root than those under uniform salinity. Root Na(+) efflux in the low salinity side was greatly enhanced by the higher salinity side. NaCl-induced Na(+) efflux and H(+) influx were inhibited by amiloride and sodium orthovanadate, suggesting that root Na(+) extrusion was probably due to active Na(+)/H(+) antiport across the plasma membrane. Improved plant growth under non-uniform salinity was thus attributed to increased water use, reduced leaf Na(+) concentration, transport of excessive foliar Na(+) to the low salinity side, and enhanced Na(+) efflux from the low salinity root.

  4. Synthesis of Na-A and/or Na-X zeolite/porous carbon composites from carbonized rice husk

    Science.gov (United States)

    Katsuki, Hiroaki; Komarneni, Sridhar

    2009-07-01

    Na-A and/or Na-X zeolite/porous carbon composites were prepared under hydrothermal conditions by NaOH dissolution of silica first from carbonized rice husk followed by addition of NaAlO 2 and in situ crystallization of zeolites i.e., using a two-step process. When a one-step process was used, both Na-A and Na-X zeolites crystallized on the surface of carbon. Na-A or Na-X zeolite crystals were prepared on the porous carbonized rice husk at 90 °C for 2-6 h by changing the SiO 2/Al 2O 3, H 2O/Na 2O and Na 2O/SiO 2 molar ratios of precursors in the two-step process. The surface area and NH 4+-cation exchange capacity (CEC) of Na-A zeolite/porous carbon were found to be 171 m 2/g and 506 meq/100 g, respectively, while those of Na-X zeolite/porous carbon composites were 676 m 2/g and 317 meq/100 g, respectively. Na-A and Na-X zeolites are well-known microporous and hydrophilic materials while carbonized rice husk was found to be mesoporous (pores of ˜3.9 nm) and hydrophobic. These hybrid microporous-mesoporous and hydrophilic-hydrophobic composites are expected to be useful for decontamination of metal cations as well as organic contaminants simultaneously.

  5. Random Tensor Theory: Extending Random Matrix Theory to Mixtures of Random Product States

    Science.gov (United States)

    Ambainis, Andris; Harrow, Aram W.; Hastings, Matthew B.

    2012-02-01

    We consider a problem in random matrix theory that is inspired by quantum information theory: determining the largest eigenvalue of a sum of p random product states in {(mathbb {C}^d)^{⊗ k}}, where k and p/ d k are fixed while d → ∞. When k = 1, the Marčenko-Pastur law determines (up to small corrections) not only the largest eigenvalue ({(1+sqrt{p/d^k})^2}) but the smallest eigenvalue {(min(0,1-sqrt{p/d^k})^2)} and the spectral density in between. We use the method of moments to show that for k > 1 the largest eigenvalue is still approximately {(1+sqrt{p/d^k})^2} and the spectral density approaches that of the Marčenko-Pastur law, generalizing the random matrix theory result to the random tensor case. Our bound on the largest eigenvalue has implications both for sampling from a particular heavy-tailed distribution and for a recently proposed quantum data-hiding and correlation-locking scheme due to Leung and Winter. Since the matrices we consider have neither independent entries nor unitary invariance, we need to develop new techniques for their analysis. The main contribution of this paper is to give three different methods for analyzing mixtures of random product states: a diagrammatic approach based on Gaussian integrals, a combinatorial method that looks at the cycle decompositions of permutations and a recursive method that uses a variant of the Schwinger-Dyson equations.

  6. Muscle K+, Na+, and Cl- disturbances and Na+-K+ pump inactivation: implications for fatigue

    DEFF Research Database (Denmark)

    McKenna, Michael J; Bangsbo, Jens; Renaud, Jean-Marc

    2008-01-01

    Membrane excitability is a critical regulatory step in skeletal muscle contraction and is modulated by local ionic concentrations, conductances, ion transporter activities, temperature, and humoral factors. Intense fatiguing contractions induce cellular K(+) efflux and Na(+) and Cl(-) influx......, these ionic changes depolarize sarcolemmal and t-tubular membranes to depress tetanic force and are thus likely to contribute to fatigue. Interestingly, less severe local ionic changes can also augment subtetanic force, suggesting that they may potentiate muscle contractility early in exercise. Increased Na......(+)-K(+)-ATPase activity during exercise stabilizes Na(+) and K(+) concentration gradients and membrane excitability and thus protects against fatigue. However, during intense contraction some Na(+)-K(+) pumps are inactivated and together with further ionic disturbances, likely precipitate muscle fatigue....

  7. Rare kaon decay measurements with NA48/NA62 minumum bias data

    Energy Technology Data Exchange (ETDEWEB)

    Cassese, Antonio, E-mail: cassese@fi.infn.it [INFN Sez. di Firenze, Via G. Sansone 1, 50019 Sesto Fiorentino (Italy); Università degli Studi di Firenze, Dipartimento di Fisica, Via G. Sansone 1, 50019 Sesto Fiorentino (Italy)

    2013-01-15

    The NA62 and NA48/2 experiments at CERN collected a large sample of charged kaon decays with a low intensity beam and minimum bias trigger conditions in 2004 (NA48/2) and 2007 (NA62). This allowed measurements of a number of rare decays that are difficult to address in conventional high intensity experiments with highly selective trigger conditions. In particular, large samples of K{sup ±}→π{sup ±}γγ and K{sup ±}→e{sup ±{sup ({sup −{sup −{sup )}}}}}νγ decays have been collected, allowing precision tests of the Chiral Perturbation Theory. The status and first results of these analyses are presented.

  8. Regulation of cardiac myocyte contractility by phospholemman: Na+/Ca2+ exchange versus Na+ -K+ -ATPase.

    Science.gov (United States)

    Song, Jianliang; Zhang, Xue-Qian; Wang, JuFang; Cheskis, Ellina; Chan, Tung O; Feldman, Arthur M; Tucker, Amy L; Cheung, Joseph Y

    2008-10-01

    Phospholemman (PLM) regulates cardiac Na(+)/Ca(2+) exchanger (NCX1) and Na(+)-K(+)-ATPase in cardiac myocytes. PLM, when phosphorylated at Ser(68), disinhibits Na(+)-K(+)-ATPase but inhibits NCX1. PLM regulates cardiac contractility by modulating Na(+)-K(+)-ATPase and/or NCX1. In this study, we first demonstrated that adult mouse cardiac myocytes cultured for 48 h had normal surface membrane areas, t-tubules, and NCX1 and sarco(endo)plasmic reticulum Ca(2+)-ATPase levels, and retained near normal contractility, but alpha(1)-subunit of Na(+)-K(+)-ATPase was slightly decreased. Differences in contractility between myocytes isolated from wild-type (WT) and PLM knockout (KO) hearts were preserved after 48 h of culture. Infection with adenovirus expressing green fluorescent protein (GFP) did not affect contractility at 48 h. When WT PLM was overexpressed in PLM KO myocytes, contractility and cytosolic Ca(2+) concentration ([Ca(2+)](i)) transients reverted back to those observed in cultured WT myocytes. Both Na(+)-K(+)-ATPase current (I(pump)) and Na(+)/Ca(2+) exchange current (I(NaCa)) in PLM KO myocytes rescued with WT PLM were depressed compared with PLM KO myocytes. Overexpressing the PLMS68E mutant (phosphomimetic) in PLM KO myocytes resulted in the suppression of I(NaCa) but had no effect on I(pump). Contractility, [Ca(2+)](i) transient amplitudes, and sarcoplasmic reticulum Ca(2+) contents in PLM KO myocytes overexpressing the PLMS68E mutant were depressed compared with PLM KO myocytes overexpressing GFP. Overexpressing the PLMS68A mutant (mimicking unphosphorylated PLM) in PLM KO myocytes had no effect on I(NaCa) but decreased I(pump). Contractility, [Ca(2+)](i) transient amplitudes, and sarcoplasmic reticulum Ca(2+) contents in PLM KO myocytes overexpressing the S68A mutant were similar to PLM KO myocytes overexpressing GFP. We conclude that at the single-myocyte level, PLM affects cardiac contractility and [Ca(2+)](i) homeostasis primarily by its direct

  9. A Mixed Effects Randomized Item Response Model

    Science.gov (United States)

    Fox, J.-P.; Wyrick, Cheryl

    2008-01-01

    The randomized response technique ensures that individual item responses, denoted as true item responses, are randomized before observing them and so-called randomized item responses are observed. A relationship is specified between randomized item response data and true item response data. True item response data are modeled with a (non)linear…

  10. Evaluating the efficacy of Tui Na in treatment of childhood anorexia: a meta-analysis.

    Science.gov (United States)

    Xia, Qiao Cui; Feng, Zhang Xin; Ping, Cai Xiao

    2014-01-01

    Medical practitioners are now seeing more children younger than 15 y who are developing childhood anorexia. Hua Tuo chiropractic treatments are an ancient and practical massage therapy and are a type of Tui Na therapy, which has been used for curing childhood anorexia for thousands of years in China. Research literature suggests that chiropractic care produces outcomes at least comparable with alternative treatments. The research team intended to perform a systematic review to identify and synthesize evidence on the efficacy of Tui Na for treatment of childhood anorexia. Systematic searches were conducted for studies evaluating Tui Na therapy in electronic databases MEDLINE, EMBASE, PsychINFO, the Cochrane Library, the Cumulative Index to Nursing and Allied Health Literature, the Midwives Information and Resource Service, the Health Management Information Consortium, the Health Management and Information Service, PubMed, the Chinese National Knowledge Infrastructure (CNKI), the Chinese Biomedical Literature Database (CBM), the Chinese Scientific Journal Database VIP, the Cumulative Index to Nursing and Allied Health Literature (CINAHL), and the Chinese Clinical Trial Register-from inception to November 2011. The research team hand-searched reference lists and journals, extracted data from the papers, and assessed the quality of the research. Participants of the reviewed studies were infants and children younger than 15 y. Of the 109 papers identified, 3 papers reported on randomized, controlled trials (RCTs) involving 332 patients; 45 covered cohort or quasi-experimental studies; and 61 discussed nonintervention studies. Meta-analysis results from the 3 RCTs showed that Tui Na can improve the curative effect compared with oral medicine that is used for infants and young children with anorexia and can also increase a child's weight. The level of evidence reported was mixed, but given the available evidence, the research team concluded that Tui Na therapy was a

  11. Role of Na+ conductance, Na+-H+ exchange, and Na+-K+-2Cl− symport in the regulatory volume increase of rat hepatocytes

    Science.gov (United States)

    Wehner, Frank; Tinel, Hanna

    1998-01-01

    In rat hepatocytes under hypertonic stress, the entry of Na+ (which is thereafter exchanged for K+ via Na+-K+-ATPase) plays the key role in regulatory volume increase (RVI).In the present study, the contributions of Na+ conductance, Na+-H+ exchange and Na+-K+-2Cl− symport to this process were quantified in confluent primary cultures by means of intracellular microelectrodes and cable analysis, microfluorometric determinations of cell pH and buffer capacity, and measurements of frusemide (furosemide)/bumetanide-sensitive 86Rb+ uptake, respectively. Osmolarity was increased from 300 to 400 mosmol l−1 by addition of sucrose.The experiments indicate a relative contribution of approximately 4:1:1 to hypertonicity-induced Na+ entry for the above-mentioned transporters and the overall Na+ yield equalled 51 mmol l−1 (10 min)−1.This Na+ gain is in good agreement with the stimulation of Na+ extrusion via Na+-K+-ATPase plus the actual increase in cell Na+, namely 55 mmol l−1 (10 min)−1, as was determined on the basis of ouabain-sensitive 86Rb+ uptake and by means of Na+-sensitive microelectrodes, respectively.The overall increase in Na+ and K+ activity plus the expected concomitant increase in cell Cl− equalled 68 mmol l−1, which fits well with the increase in osmotic activity expected to occur from an initial cell shrinkage to 87.5 % and a RVI to 92.6 % of control, namely 53 mosmol l−1.The prominent role of Na+ conductance in the RVI of rat hepatocytes could be confirmed on the basis of the pharmacological profile of this process, which was characterized by means of confocal laser-scanning microscopy. PMID:9481677

  12. Bupivacaína racêmica, levobupivacaína e ropivacaína em anestesia loco-regional para oftalmologia: um estudo comparativo Racemic bupivacaine, levobupi vacaine and ropivacaine in regional anesthesia for ophtalmology: a comparative study

    Directory of Open Access Journals (Sweden)

    Edno Magalhães

    2004-04-01

    Full Text Available OBJETIVO: A bupivacaína racêmica, utilizada largamente em anestesia peribulbar devido à boa qualidade de bloqueio motor, apresenta menor margem de segurança para cardiotoxicidade em relação a ropivacaína e bupivacaína levógira. O objetivo deste estudo foi comparar o grau de bloqueio motor e alteração da pressão intra-ocular (PIO em anestesia peribulbar produzida pela bupivacaína racêmica, levobupivacaína e ropivacaína. MÉTODOS: Noventa e sete pacientes, estado físico I e II da classificação da Sociedade Americana de Anestesiologistas, submetidos a anestesia peribulbar, foram divididos em três grupos: grupo A-(n=16 bupivacaína racêmica 0,75% com adrenalina 1:200.000; grupo B -(n=16 bupivacaína levógira 0,75% com adrenalina 1:200.000; grupo C -(n=15 ropivacaína 0,75%. Utilizou-se 7ml da solução anestésica com 280 UI de hialuronidase, em punção única no rebordo orbital inferior. Foram registrados a PIO e grau de bloqueio motor 5 minutos antes da punção e 1, 2, 3, 4, 5 e 10 minutos após a punção. O bloqueio motor foi avaliado pela escala de Nicoll. Para a análise estatística, foram utilizados os testes de Wilcoxon, análise de freqüência simples e t de Student. Foi considerado significativo pBACKGROUND AND OBJECTIVE: Racemic bupivacaine, used in peribulbar anesthesia owing to its high potential to promote motor blockade, presents a smaller safety margin for cardiotoxicity in relation to ropivacaine and levobupivacaine. The objective of this study was to compare the degree of motor blockade and alteration of intraocular pressure (IOP produced by racemic bupivacaine, levobupivacaine and ropivacaine in peribulbar block. METHOD: Ninety seven patients, ASA physical status I and II, submitted to peribulbar anesthesia, were randomly allocated into three groups: group A-(n=16 receiving racemic bupivacaine 0.75% with epinephrine 1:200.000; group B -(n=16 levobupivacaine 0.75% with epinephrine 1:200.000; group C -(n=15

  13. Hidroginástica na terceira idade

    Directory of Open Access Journals (Sweden)

    Karla Campos de Paula

    1998-02-01

    Full Text Available O processo de envelhecimento no indivíduo saudável está relacionado com inúmeras alterações psicológicas e físicas que interferem na área motora, concorrendo para a inatividade e contribuindo para o aparecimento e agravamento de determinadas doenças, além de influenciar negativamente a realização das atividades de vida diária. Portanto, a prática de atividade física é fundamental para o idoso, não só na prevenção de doenças como na reabilitação de suas habilidades motoras, promovendo um estilo de vida saudável que é fator preponderante para a melhoria da qualidade de vida. Contudo, algumas precauções devem ser adotadas na prescrição da atividade direcionada para o idoso, a fim de que esta seja segura e prazerosa. Dentre os exercícios mais adequados aos idosos estão a caminhada, o ciclismo, a natação e a hidroginástica. Devido a sua grande procura, a hidroginástica vem aumentando o número de adeptos na terceira idade. Ela propicia ao idoso o aumento de sua capacidade aeróbia, força muscular, flexibilidade articular e o treinamento de habilidades específicas como equilíbrio e coordenação motora. Soma-se ainda o fato de esta atividade oferecer ambiente de relaxamento e incentivo ao contato social, atuando no combate ao estresse, depressão, na melhoria da autopercepção corporal e da auto-estima. Devemos, então, estar atentos às particularidades da hidroginástica, a fim de aproveitar todas as vantagens que esta oferece para o programa de exercícios direcionado para a terceira idade.

  14. Asymptotics of weighted random sums

    DEFF Research Database (Denmark)

    Corcuera, José Manuel; Nualart, David; Podolskij, Mark

    2014-01-01

    In this paper we study the asymptotic behaviour of weighted random sums when the sum process converges stably in law to a Brownian motion and the weight process has continuous trajectories, more regular than that of a Brownian motion. We show that these sums converge in law to the integral...

  15. Privacy preserving randomized gossip algorithms

    KAUST Repository

    Hanzely, Filip

    2017-06-23

    In this work we present three different randomized gossip algorithms for solving the average consensus problem while at the same time protecting the information about the initial private values stored at the nodes. We give iteration complexity bounds for all methods, and perform extensive numerical experiments.

  16. Common Randomness Principles of Secrecy

    Science.gov (United States)

    Tyagi, Himanshu

    2013-01-01

    This dissertation concerns the secure processing of distributed data by multiple terminals, using interactive public communication among themselves, in order to accomplish a given computational task. In the setting of a probabilistic multiterminal source model in which several terminals observe correlated random signals, we analyze secure…

  17. Supersymmetry in Random Matrix Theory

    OpenAIRE

    Guhr, Thomas

    2010-01-01

    Supersymmetry is nowadays indispensable for many problems in Random Matrix Theory. It is presented here with an emphasis on conceptual and structural issues. An introduction to supermathematics is given. The Hubbard-Stratonovich transformation as well as its generalization and superbosonization are explained. The supersymmetric non-linear sigma model, Brownian motion in superspace and the color-flavor transformation are discussed.

  18. Chaos, complexity, and random matrices

    Science.gov (United States)

    Cotler, Jordan; Hunter-Jones, Nicholas; Liu, Junyu; Yoshida, Beni

    2017-11-01

    Chaos and complexity entail an entropic and computational obstruction to describing a system, and thus are intrinsically difficult to characterize. In this paper, we consider time evolution by Gaussian Unitary Ensemble (GUE) Hamiltonians and analytically compute out-of-time-ordered correlation functions (OTOCs) and frame potentials to quantify scrambling, Haar-randomness, and circuit complexity. While our random matrix analysis gives a qualitatively correct prediction of the late-time behavior of chaotic systems, we find unphysical behavior at early times including an O(1) scrambling time and the apparent breakdown of spatial and temporal locality. The salient feature of GUE Hamiltonians which gives us computational traction is the Haar-invariance of the ensemble, meaning that the ensemble-averaged dynamics look the same in any basis. Motivated by this property of the GUE, we introduce k-invariance as a precise definition of what it means for the dynamics of a quantum system to be described by random matrix theory. We envision that the dynamical onset of approximate k-invariance will be a useful tool for capturing the transition from early-time chaos, as seen by OTOCs, to late-time chaos, as seen by random matrix theory.

  19. Fatigue Reliability under Random Loads

    DEFF Research Database (Denmark)

    Talreja, R.

    1979-01-01

    We consider the problem of estimating the probability of survival (non-failure) and the probability of safe operation (strength greater than a limiting value) of structures subjected to random loads. These probabilities are formulated in terms of the probability distributions of the loads and the...... propagation stage. The consequences of this behaviour on the fatigue reliability are discussed....

  20. Stalled ERP at Random Textiles

    Science.gov (United States)

    Brumberg, Robert; Kops, Eric; Little, Elizabeth; Gamble, George; Underbakke, Jesse; Havelka, Douglas

    2016-01-01

    Andre Raymond, Executive Vice President of Sales and Marketing for Random Textiles Co. Inc. (RTC), stood in front of the podium to address his team of 70 sales consultants in Las Vegas, NV. The organization had increased market share and achieved record sales over the past three years; however, in the shadow of this success lurked an obstacle that…