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Sample records for ran domly selected

  1. Tuisland. Karin Brynard. Kaapstad: Penguin Ran- dom House Suid ...

    African Journals Online (AJOL)

    Karin Brynard. Kaapstad: Penguin Ran- dom House Suid-Afrika, 2016. 576 pp. ISBN 978-1-4152-0693-5,. ISBN 978-1-4152-0668-3,. ISBN 978-1-4125-0669-0. DOI: http://dx.doi.org/10.17159/tvl.v.54i1.29. Tuisland (2016) is oud-joernalis Karin. Brynard se derde spanningsroman. Haar debuut, Plaasmoord (2009), is met die.

  2. RAN translation at C9orf72-associated repeat expansions is selectively enhanced by the integrated stress response.

    Science.gov (United States)

    Green, Katelyn M; Glineburg, M Rebecca; Kearse, Michael G; Flores, Brittany N; Linsalata, Alexander E; Fedak, Stephen J; Goldstrohm, Aaron C; Barmada, Sami J; Todd, Peter K

    2017-12-08

    Repeat-associated non-AUG (RAN) translation allows for unconventional initiation at disease-causing repeat expansions. As RAN translation contributes to pathogenesis in multiple neurodegenerative disorders, determining its mechanistic underpinnings may inform therapeutic development. Here we analyze RAN translation at G4C2 repeat expansions that cause C9orf72-associated amyotrophic lateral sclerosis and frontotemporal dementia (C9RAN) and at CGG repeats that cause fragile X-associated tremor/ataxia syndrome. We find that C9RAN translation initiates through a cap- and eIF4A-dependent mechanism that utilizes a CUG start codon. C9RAN and CGG RAN are both selectively enhanced by integrated stress response (ISR) activation. ISR-enhanced RAN translation requires an eIF2α phosphorylation-dependent alteration in start codon fidelity. In parallel, both CGG and G4C2 repeats trigger phosphorylated-eIF2α-dependent stress granule formation and global translational suppression. These findings support a model whereby repeat expansions elicit cellular stress conditions that favor RAN translation of toxic proteins, creating a potential feed-forward loop that contributes to neurodegeneration.

  3. Selective Impairment of a Subset of Ran-GTP-binding Domains of Ran-binding Protein 2 (Ranbp2) Suffices to Recapitulate the Degeneration of the Retinal Pigment Epithelium (RPE) Triggered by Ranbp2 Ablation*

    Science.gov (United States)

    Patil, Hemangi; Saha, Arjun; Senda, Eugene; Cho, Kyoung-in; Haque, MdEmdadul; Yu, Minzhong; Qiu, Sunny; Yoon, Dosuk; Hao, Ying; Peachey, Neal S.; Ferreira, Paulo A.

    2014-01-01

    Retinal pigment epithelium (RPE) degeneration underpins diseases triggered by disparate genetic lesions, noxious insults, or both. The pleiotropic Ranbp2 controls the expression of intrinsic and extrinsic pathological stressors impinging on cellular viability. However, the physiological targets and mechanisms controlled by Ranbp2 in tissue homeostasis, such as RPE, are ill defined. We show that mice, RPE-cre::Ranbp2−/−, with selective Ranbp2 ablation in RPE develop pigmentary changes, syncytia, hypoplasia, age-dependent centrifugal and non-apoptotic degeneration of the RPE, and secondary leakage of choriocapillaris. These manifestations are accompanied by the development of F-actin clouds, metalloproteinase-11 activation, deregulation of expression or subcellular localization of critical RPE proteins, atrophic cell extrusions into the subretinal space, and compensatory proliferation of peripheral RPE. To gain mechanistic insights into what Ranbp2 activities are vital to the RPE, we performed genetic complementation analyses of transgenic lines of bacterial artificial chromosomes of Ranbp2 harboring loss of function of selective Ranbp2 domains expressed in a Ranbp2−/− background. Among the transgenic lines produced, only TgRBD2/3*-HA::RPE-cre::Ranbp2−/−-expressing mutations, which selectively impair binding of RBD2/3 (Ran-binding domains 2 and 3) of Ranbp2 to Ran-GTP, recapitulate RPE degeneration, as observed with RPE-cre::Ranbp2−/−. By contrast, TgRBD2/3*-HA expression rescues the degeneration of cone photoreceptors lacking Ranbp2. The RPE of RPE-cre::Ranbp2−/− and TgRBD2/3*-HA::RPE-cre::Ranbp2−/− share proteostatic deregulation of Ran GTPase, serotransferrin, and γ-tubulin and suppression of light-evoked electrophysiological responses. These studies unravel selective roles of Ranbp2 and its RBD2 and RBD3 in RPE survival and functions. We posit that the control of Ran GTPase by Ranbp2 emerges as a novel therapeutic target in diseases

  4. Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.

    Science.gov (United States)

    Patil, Hemangi; Saha, Arjun; Senda, Eugene; Cho, Kyoung-in; Haque, MdEmdadul; Yu, Minzhong; Qiu, Sunny; Yoon, Dosuk; Hao, Ying; Peachey, Neal S; Ferreira, Paulo A

    2014-10-24

    Retinal pigment epithelium (RPE) degeneration underpins diseases triggered by disparate genetic lesions, noxious insults, or both. The pleiotropic Ranbp2 controls the expression of intrinsic and extrinsic pathological stressors impinging on cellular viability. However, the physiological targets and mechanisms controlled by Ranbp2 in tissue homeostasis, such as RPE, are ill defined. We show that mice, RPE-cre::Ranbp2(-/-), with selective Ranbp2 ablation in RPE develop pigmentary changes, syncytia, hypoplasia, age-dependent centrifugal and non-apoptotic degeneration of the RPE, and secondary leakage of choriocapillaris. These manifestations are accompanied by the development of F-actin clouds, metalloproteinase-11 activation, deregulation of expression or subcellular localization of critical RPE proteins, atrophic cell extrusions into the subretinal space, and compensatory proliferation of peripheral RPE. To gain mechanistic insights into what Ranbp2 activities are vital to the RPE, we performed genetic complementation analyses of transgenic lines of bacterial artificial chromosomes of Ranbp2 harboring loss of function of selective Ranbp2 domains expressed in a Ranbp2(-/-) background. Among the transgenic lines produced, only Tg(RBD2/3*-HA)::RPE-cre::Ranbp2(-/-)-expressing mutations, which selectively impair binding of RBD2/3 (Ran-binding domains 2 and 3) of Ranbp2 to Ran-GTP, recapitulate RPE degeneration, as observed with RPE-cre::Ranbp2(-/-). By contrast, Tg(RBD2/3*-HA) expression rescues the degeneration of cone photoreceptors lacking Ranbp2. The RPE of RPE-cre::Ranbp2(-/-) and Tg(RBD2/3*-HA)::RPE-cre::Ranbp2(-/-) share proteostatic deregulation of Ran GTPase, serotransferrin, and γ-tubulin and suppression of light-evoked electrophysiological responses. These studies unravel selective roles of Ranbp2 and its RBD2 and RBD3 in RPE survival and functions. We posit that the control of Ran GTPase by Ranbp2 emerges as a novel therapeutic target in diseases promoting

  5. Selective incorporation of dissolved organic matter (DOM) during sea ice formation

    DEFF Research Database (Denmark)

    Müller, Susan; Vähätalo, Anssi V.; Stedmon, Colin

    2013-01-01

    as concentrations of dissolved organic carbon (DOC), dissolved organic nitrogen (DON), dissolved carbohydrates (dCHOs) and dissolved uronic acids (dUAs) were measured. Enrichment factors (EFs), calculated from salinity-normalized concentrations of DOM in bulk ice, brine and frost flowers relative to under-ice water...

  6. DOM Scripting

    CERN Document Server

    Keith, J

    2011-01-01

    In this Second Edition of the popular DOM Scripting: Web Design with JavaScript and the Document Object Model, comes a modern revision to include current best practices and guidelines. There is also full coverage of HTML5 in a new, dedicated chapter, and details on JavaScript libraries and how they can help your scripting. The book gives you everything you need to start using JavaScript and the Document Object Model to enhance your web pages with client-side dynamic effects and user-controlled animation. It shows you how JavaScript, HTML5, and Cascading Style Sheets (CSS) work together to crea

  7. Impairments in age-dependent ubiquitin proteostasis and structural integrity of selective neurons by uncoupling Ran GTPase from the Ran-binding domain 3 of Ranbp2 and identification of novel mitochondrial isoforms of ubiquitin-conjugating enzyme E2I (ubc9) and Ranbp2.

    Science.gov (United States)

    Patil, Hemangi; Yoon, Dosuk; Bhowmick, Reshma; Cai, Yunfei; Cho, Kyoung-In; Ferreira, Paulo A

    2017-09-06

    data support that Ran GTPase-dependent and independent and moonlighting roles of Ranbp2 or domains thereof and ubc9 control selectively age-dependent, neural-type and mitochondrial functions.

  8. Dom Casmurro

    Directory of Open Access Journals (Sweden)

    Agripino Grieco

    2011-12-01

    Full Text Available "Sou dos que encontram uma espécie de magnetismo suspeito em Joaquim Maria. Admiro-o resmungando contra a minha admiração. E até parece que o que mais aproxima tanta gente dele é mesmo o fato de discordar tanto dele, de se irritar tanto em dados trechos. No amor a inteligências dessas há qualquer coisa de indefinível como no vício do jogo." Foi sempre nesse tom, meio a contragosto, com raiva da sua admiração incontrolável, que Agripino Grieco escreveu sobre Machado de Assis. O autor de Dom Casmurro foi uma espécie de cachaça para esse poeta, jornalista e crítico controverso, fluminense nascido em Paraíba do Sul em 1888, às vezes tão mal humorado que se tornava divertido na sua ranzinzice. Um exemplo dessa combinação peculiar de mau humor e graça: "se pudéssemos obter a média das personagens de Machado, diríamos que sua principal criação namora viúva, lê romance francês, vai passear na Tijuca, é sovina e queima rato." Seguindo a linhagem de Sílvio Romero, que viu e recriminou em Machado o macaqueador do humorismo de Sterne, Grieco deu mais um giro no estilete romeriano, apelidando Machado de "Sterne do Cais Pharoux". Amante da frase ferina, que nem sempre vem acompanhada do julgamento justo, foi capaz de sentenciar, em pleno 1959, quando o futebol já se tornara esporte nacional e promovera grandes comoções (como a perda da Copa do Mundo para o Uruguai no Maracanã, em 1950, que "duas coisas, especificamente da zona de John Bull, não convêm absolutamente aos trópicos: o futebol e o humour." A passagem do tempo se encarregou de contradizer o crítico. Mas naqueles anos, marcados por uma verdadeira machadolatria, alimentada pelas comemorações do centenário do nascimento, em 1939, e pelas homenagens ao cinquentenário da morte, celebrados em 1958, Agripino Grieco provocou a ira de muita gente. Assim, não é de espantar o estrondo que produziram os dois livros que dedicou integralmente ao criador de Capitu

  9. RAN Translation in Huntington Disease.

    Science.gov (United States)

    Bañez-Coronel, Monica; Ayhan, Fatma; Tarabochia, Alex D; Zu, Tao; Perez, Barbara A; Tusi, Solaleh Khoramian; Pletnikova, Olga; Borchelt, David R; Ross, Christopher A; Margolis, Russell L; Yachnis, Anthony T; Troncoso, Juan C; Ranum, Laura P W

    2015-11-18

    Huntington disease (HD) is caused by a CAG ⋅ CTG expansion in the huntingtin (HTT) gene. While most research has focused on the HTT polyGln-expansion protein, we demonstrate that four additional, novel, homopolymeric expansion proteins (polyAla, polySer, polyLeu, and polyCys) accumulate in HD human brains. These sense and antisense repeat-associated non-ATG (RAN) translation proteins accumulate most abundantly in brain regions with neuronal loss, microglial activation and apoptosis, including caudate/putamen, white matter, and, in juvenile-onset cases, also the cerebellum. RAN protein accumulation and aggregation are length dependent, and individual RAN proteins are toxic to neural cells independent of RNA effects. These data suggest RAN proteins contribute to HD and that therapeutic strategies targeting both sense and antisense genes may be required for efficacy in HD patients. This is the first demonstration that RAN proteins are expressed across an expansion located in an open reading frame and suggests RAN translation may also contribute to other polyglutamine diseases. Copyright © 2015 Elsevier Inc. All rights reserved.

  10. RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism.

    Directory of Open Access Journals (Sweden)

    Azamat Aslanukov

    2006-10-01

    Full Text Available The Ran-binding protein 2 (RanBP2 is a large multimodular and pleiotropic protein. Several molecular partners with distinct functions interacting specifically with selective modules of RanBP2 have been identified. Yet, the significance of these interactions with RanBP2 and the genetic and physiological role(s of RanBP2 in a whole-animal model remain elusive. Here, we report the identification of two novel partners of RanBP2 and a novel physiological role of RanBP2 in a mouse model. RanBP2 associates in vitro and in vivo and colocalizes with the mitochondrial metallochaperone, Cox11, and the pacemaker of glycolysis, hexokinase type I (HKI via its leucine-rich domain. The leucine-rich domain of RanBP2 also exhibits strong chaperone activity toward intermediate and mature folding species of Cox11 supporting a chaperone role of RanBP2 in the cytosol during Cox11 biogenesis. Cox11 partially colocalizes with HKI, thus supporting additional and distinct roles in cell function. Cox11 is a strong inhibitor of HKI, and RanBP2 suppresses the inhibitory activity of Cox11 over HKI. To probe the physiological role of RanBP2 and its role in HKI function, a mouse model harboring a genetically disrupted RanBP2 locus was generated. RanBP2(-/- are embryonically lethal, and haploinsufficiency of RanBP2 in an inbred strain causes a pronounced decrease of HKI and ATP levels selectively in the central nervous system. Inbred RanBP2(+/- mice also exhibit deficits in growth rates and glucose catabolism without impairment of glucose uptake and gluconeogenesis. These phenotypes are accompanied by a decrease in the electrophysiological responses of photosensory and postreceptoral neurons. Hence, RanBP2 and its partners emerge as critical modulators of neuronal HKI, glucose catabolism, energy homeostasis, and targets for metabolic, aging disorders and allied neuropathies.

  11. RAN GTPase and Osteopontin in Pancreatic Cancer.

    Science.gov (United States)

    Saxena, Shivam; Gandhi, Ankit; Lim, Pei-Wen; Relles, Daniel; Sarosiek, Konrad; Kang, Christopher; Chipitsyna, Galina; Sendecki, Jocelyn; Yeo, Charles J; Arafat, Hwyda A

    2013-04-01

    Pancreatic ductal adenocarcinoma (PDA) has the worst prognosis among cancers, mainly due to the high incidence of early metastases. RAN small GTPase (RAN) is a protein that plays physiological roles in the regulation of nuclear transport and microtubule spindle assembly. RAN was recently shown to mediate the invasive functions of the prometastatic protein osteopontin (OPN) in breast cancer cells. We and others have shown previously that high levels of OPN are present in PDA. In this study, we analyzed the expression and correlation of RAN with OPN in human pancreatic lesions, and explored their regulation in PDA cell lines. Real time PCR was used to analyze RAN and OPN mRNA levels in PDA, adjacent non-malignant, and benign pancreatic tissues. Expression levels were correlated with survival and different clinicopathological parameters using different statistical methods. Transient transfection studies using OPN and RAN plasmids, and knockdown experiments using siRNA were used to examine their mutual regulation. OPN and RAN levels highly correlated with each other (pobesity, T stage, BMI, or survival. However, we found a significant association between RAN levels and perineural invasion (HR=0.79, 95% CI 0.59, 1.07; p=0.0378.). OPN and RAN colocalized in PDA tissues and cell lines. Increasing RAN expression in PDA cells induced OPN transcription and RAN silencing reduced total OPN levels. OPN did not have any significant effect on RAN transcription. The high levels of RAN in PDA and its correlation with OPN and with perineural invasion suggest that RAN may contribute to PDA metastasis and progression through the induction of OPN. RAN's role in the regulation of OPN in PDA is unique and could provide potential novel therapeutic strategies to combat PDA aggressiveness.

  12. Tackling complex turbulent flows with transient RANS

    NARCIS (Netherlands)

    Kenjeres, S.; Hanjalic, K.

    2009-01-01

    This article reviews some recent applications of the transient-Reynoldsaveraged Navier–Stokes (T-RANS) approach in simulating complex turbulent flows dominated by externally imposed body forces, primarily by thermal buoyancy and the Lorentz force. The T-RANS aims at numerical resolving unsteady

  13. The Ran pathway in Drosophila melanogaster mitosis

    Directory of Open Access Journals (Sweden)

    James G Wakefield

    2015-11-01

    Full Text Available Over the last two decades, the small GTPase Ran has emerged as a central regulator of both mitosis and meiosis, particularly in the generation, maintenance and regulation of the microtubule (MT-based bipolar spindle. Ran-regulated pathways in mitosis bear many similarities to the well-characterized functions of Ran in nuclear transport and, as with transport, the majority of these mitotic effects are mediated through affecting the physical interaction between karyopherins and Spindle Assembly Factors (SAFs - a loose term describing proteins or protein complexes involved in spindle assembly through promoting nucleation, stabilization, and/or depolymerization of MTs, through anchoring MTs to specific structures such as centrosomes, chromatin or kinetochores, or through sliding MTs along each other to generate the force required to achieve bipolarity. As such, the Ran-mediated pathway represents a crucial functional module within the wider spindle assembly landscape. Research into mitosis using the model organism Drosophila melanogaster has contributed substantially to our understanding of centrosome and spindle function. However, in comparison to mammalian systems, very little is known about the contribution of Ran-mediated pathways in Drosophila mitosis. This article sets out to summarize our understanding of the roles of the Ran pathway components in Drosophila mitosis, focusing on the syncytial blastoderm embryo, arguing that, far from being superfluous, it can provide important insights into the conserved functions on Ran during spindle formation.

  14. Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene.

    NARCIS (Netherlands)

    Fauser, S.; Aslanukov, A.; Roepman, R.; Ferreira, P.A.

    2001-01-01

    The Ran-binding protein 2 (RanBP2) is a giant scaffold and mosaic cyclophilin-related nucleoporin implicated in the Ran-GTPase cycle. There are no orthologs of the RanBP2 gene in yeast and Drosophila genomes. In humans, this bona fide gene is partially duplicated in a RanBP2 gene cluster and lies in

  15. Applicability of RANS, DES and LES in propeller flow noise

    Directory of Open Access Journals (Sweden)

    LU Li

    2017-12-01

    Full Text Available [Objectives] In order to study the applicability of different turbulence models in propeller flow noise prediction, taking the DTMB 4119 propeller as the research object, the numerical simulation method is used to calculate the frequency domain noise under the non-uniform flow field.[Methods] First, the hydrodynamic coefficient and surface pressure distribution coefficient are obtained via the RANS method and the accuracy of the flow field simulation is verified by comparing it with the experimental data. Next,the pulsating pressures obtained by RANS, DES and LES are considered as the sound source respectively, and combined with the acoustic boundary element method to predict the radiation noise.[Results] The results show that spectral noise is the main contributor to total noise; when noise on 1 BPF is predicted, the results obtained by the three methods are very similar, so we can use RANS to predict noise quickly; when noise on the high order of BPF needs to be predicted, the calculation results of LES are better.[Conclusions] In noise prediction, the appropriate turbulence simulation method can be selected according to the demand.

  16. Overexpression of Ran gene from Lepidium latifolium L. (LlaRan) renders transgenic tobacco plants hypersensitive to cold stress.

    Science.gov (United States)

    Sinha, Vimlendu Bhushan; Grover, Atul; Singh, Sadhana; Pande, Veena; Ahmed, Zakwan

    2014-09-01

    Ran is a multifunctional small GTPase involved in important cellular activities like nucleocytoplasmic transport, mitotic spindle assembly, nuclear envelope formation, etc., but is also known to be differentially expressed in response to abiotic stress, particularly low temperature. We have over-expressed Lepidium latifolium (Fam. Brassicaceae) Ran gene in tobacco to study the response of the plants to cold stress (24 h; 4 °C). Transformation of the tobacco plants was verified using PCR targeting Ran gene and co-transformed selectable marker gene nptII. Segregation in Mendelian ratios was validated in five transgenic lines by germination of T1 and T2 seeds on moist filter papers containing 150 mg/l kanamycin. Higher levels of electrolyte leakage and lipid peroxidation pointed towards hypersensitivity of plants. Similarly, lesser proline accumulation compared to wild types also indicated susceptibility of plants to death under chilling conditions. Specific activity of antioxidant enzymes superoxide dismutase and glutathione reductase was also measured under stressed and control conditions. A variation was observed across the different lines, and four out of five lines showed lesser specific activity compared to wild type plants, thus indicating reduced capability of scavenging free radicals. In totality, a strong evidence on induced hypersensitivity to cold stress has been collected which may further be helpful in designing appropriate strategies for engineering crop plants for survival under cold stress conditions.

  17. [Investigations on the influence of selected compulsory measures on clinically relevant haematological and blood-chemical parameters of racing pigeons (Columba livia f. dom.)].

    Science.gov (United States)

    Krautwald-Junghanns, M E; Bartels, T; Richter, A; Pees, M

    2006-10-01

    In the presented study the influence of stress and environmental factors on selected haematological and blood-chemical parameters in racing pigeons was examined. Blood was taken at three defined days and haematological as well as blood-chemical parameters of clinical relevance were determined. In comparison to reference values published for pigeons, the majority of the values obtained in this study were within physiological borders. The daily handling of the pigeons did not have any significant effect on the examined parameters. Also the heterophile/lymphocyte ratio did not show any changes characteristic of a stress reaction. In contrast, after change of the housing dies with pigeons originating normally from a flock, the first blood sampling should be performed after a 4 or 5-day lasting period of acclimatisation to the the individual housing conditions.

  18. Chromosomal association of Ran during meiotic and mitotic divisions.

    Science.gov (United States)

    Hinkle, Beth; Slepchenko, Boris; Rolls, Melissa M; Walther, Tobias C; Stein, Pascal A; Mehlmann, Lisa M; Ellenberg, Jan; Terasaki, Mark

    2002-12-01

    Recent studies in Xenopus egg extracts indicate that the small G protein Ran has a central role in spindle assembly and nuclear envelope reformation. We determined Ran localization and dynamics in cells during M phase. By immunofluorescence, Ran is accumulated on the chromosomes of meiosis-II-arrested Xenopus eggs. In living cells, fluorescently labeled Ran associated with the chromosomes in Xenopus and remained associated during anaphase when eggs were artificially activated. Fluorescent Ran associated with chromosomes in mouse eggs, during meiotic maturation and early embryonic divisions in starfish, and to a lesser degree during mitosis of a cultured mammalian cell line. Chromosomal Ran undergoes constant flux. From photobleach experiments in immature starfish oocytes, chromosomal Ran has a k(off) of approximately 0.06 second(-1), and binding analysis suggests that there is a single major site. The chromosomal interactions may serve to keep Ran-GTP in the vicinity of the chromosomes for spindle assembly and nuclear envelope reformation.

  19. O dom de jogar bola

    Directory of Open Access Journals (Sweden)

    Sérgio Settani Giglio

    2008-12-01

    Full Text Available Este artigo tem como objetivo investigar como a categoria dom e seus significados interagem com a construção sociocultural do fenômeno futebol. A categoria foi trabalhada a partir da sua relação com a magia e a fé, necessárias num ambiente tão supersticioso como o do futebol brasileiro. A validação do dom enquanto objeto imperativo à compreensão dos êxitos e fracassos no futebol é algo compartilhado não só pelos jogadores, como também pela imprensa esportiva e pelos torcedores. A eficácia simbólica do dom é validada em ato mágico ao ser compartilhada e aceita por seus próprios criadores e consumidores, a ponto de transformar o rico contexto de aprendizado para o futebol, vivido no Brasil, em um simples golpe da sorte: nascer ou não com o dom.This paper aims at investigating how being gifted, as a category for classifying football players, interacts with the sociocultural construction of the sporting phenomenon. The category and its meanings were analyzed in relation to magic and faith, since the Brazilian football environment is very superstitious. Football players and fans and also the press usually attribute success and failure in the sport to being gifted. The symbolic efficacy of the natural ability is validated as it is accepted and conveyed by its own creators and consumers as a magical fact. That sense causes them to signify the rich Brazilian context of learning how to play football as a matter of luck: players are either gifted or non-gifted.

  20. Evaluation of energy and cost savings in mobile Cloud RAN

    DEFF Research Database (Denmark)

    Checko, Aleksandra; Christiansen, Henrik Lehrmann; Berger, Michael Stübert

    2013-01-01

    The load in mobile networks is subject to variations during the day, due to user mobility and varying network average usage. Therefore, the traditional or Distributed Radio Access Network (D-RAN) architecture, where the BaseBand processing Units (BBUs) are assigned statically to a number of cells...... using OPNET Modeler. A real case scenario is built upon the mobile traffic forecast for year 2017, a number of recommendations on traffic models and a proposed C-RAN implementation. The results achieved show that the maximum statistical multiplexing gain for user plane traffic in C-RAN architecture is 4......, is sub optimal, comparing to a novel, cloud based architecture called Cloud Radio Access Network (C-RAN). In C-RAN a group of cells shares processing resources, and hence benefit from statistical multiplexing gain is expected. In this paper, the energy and cost savings in C-RAN are evaluated numerically...

  1. An Arabidopsis Ran-binding protein, AtRanBP1c, is a co-activator of Ran GTPase-activating protein and requires the C-terminus for its cytoplasmic localization

    Science.gov (United States)

    Kim, Soo-Hwan; Roux, Stanley J.

    2003-01-01

    Ran-binding proteins (RanBPs) are a group of proteins that bind to Ran (Ras-related nuclear small GTP-binding protein), and thus either control the GTP/GDP-bound states of Ran or help couple the Ran GTPase cycle to a cellular process. AtRanBP1c is a Ran-binding protein from Arabidopsis thaliana (L.) Heynh. that was recently shown to be critically involved in the regulation of auxin-induced mitotic progression [S.-H. Kim et al. (2001) Plant Cell 13:2619-2630]. Here we report that AtRanBP1c inhibits the EDTA-induced release of GTP from Ran and serves as a co-activator of Ran-GTPase-activating protein (RanGAP) in vitro. Transient expression of AtRanBP1c fused to a beta-glucuronidase (GUS) reporter reveals that the protein localizes primarily to the cytosol. Neither the N- nor C-terminus of AtRanBP1c, which flank the Ran-binding domain (RanBD), is necessary for the binding of PsRan1-GTP to the protein, but both are needed for the cytosolic localization of GUS-fused AtRanBP1c. These findings, together with a previous report that AtRanBP1c is critically involved in root growth and development, imply that the promotion of GTP hydrolysis by the Ran/RanGAP/AtRanBP1c complex in the cytoplasm, and the resulting concentration gradient of Ran-GDP to Ran-GTP across the nuclear membrane could be important in the regulation of auxin-induced mitotic progression in root tips of A. thaliana.

  2. The Anatomy of the RAN-Reading Relationship

    Science.gov (United States)

    Georgiou, George K.; Parrila, Rauno; Papadopoulos, Timothy C.

    2016-01-01

    The purpose of this study was to contrast three models of the RAN-reading relationship derived from the most prominent theoretical accounts of how RAN is related to reading: the phonological processing, the orthographic processing and the speed of processing accounts. Grade 4 Greek-speaking children (n = 208; 114 girls, 94 boys; mean…

  3. Principiel dom om familiesammenføring

    DEFF Research Database (Denmark)

    Storgaard, Louise Halleskov

    2017-01-01

    Blogindlæg om Østre Landsrets dom af 19. maj 2017 om tre-års-reglen i udlændingelovens § 9, stk. 1, nr. 1, litra d......Blogindlæg om Østre Landsrets dom af 19. maj 2017 om tre-års-reglen i udlændingelovens § 9, stk. 1, nr. 1, litra d...

  4. The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes.

    Science.gov (United States)

    Ritterhoff, Tobias; Das, Hrishikesh; Hofhaus, Götz; Schröder, Rasmus R; Flotho, Annette; Melchior, Frauke

    2016-05-10

    Continuous cycles of nucleocytoplasmic transport require disassembly of transport receptor/Ran-GTP complexes in the cytoplasm. A basic disassembly mechanism in all eukaryotes depends on soluble RanGAP and RanBP1. In vertebrates, a significant fraction of RanGAP1 stably interacts with the nucleoporin RanBP2 at a binding site that is flanked by FG-repeats and Ran-binding domains, and overlaps with RanBP2's SUMO E3 ligase region. Here, we show that the RanBP2/RanGAP1*SUMO1/Ubc9 complex functions as an autonomous disassembly machine with a preference for the export receptor Crm1. We describe three in vitro reconstituted disassembly intermediates, which show binding of a Crm1 export complex via two FG-repeat patches, cargo-release by RanBP2's Ran-binding domains and retention of free Crm1 at RanBP2 after Ran-GTP hydrolysis. Intriguingly, all intermediates are compatible with SUMO E3 ligase activity, suggesting that the RanBP2/RanGAP1*SUMO1/Ubc9 complex may link Crm1- and SUMO-dependent functions.

  5. The contribution of lexical access speed to RAN and reading

    DEFF Research Database (Denmark)

    Poulsen, Mads

    Purpose: The study investigated why and when rapid automatised naming is a predictor of reading. Specifically, we tested the hypotheses that (1) RAN-objects predicts reading because it is a measure of lexical (e.g. phonological) access speed, but (2) that RAN only becomes a predictor of reading...... development once a certain level of phonological recoding proficiency has been reached. Method: Forty Danish students without reading difficulties were administered tests of reading speed and accuracy, phoneme awareness, RAN-objects, timed confrontation picture naming, and visio-motor reaction time....... The students were sampled from two age groups representing two levels of recoding proficiency: Beginning readers in Grade 2-3 and proficient decoders in grade 5-6. We conducted hierarchical regression analyses on reading speed and accuracy to determine whether the relationship between RAN and reading...

  6. 5th Symposium on Hybrid RANS-LES Methods

    CERN Document Server

    Haase, Werner; Peng, Shia-Hui; Schwamborn, Dieter

    2015-01-01

    This book gathers the proceedings of the Fifth Symposium on Hybrid RANS-LES Methods, which was held on March 19-21 in College Station, Texas, USA. The different chapters, written by leading experts, reports on the most recent developments in flow physics modelling, and gives a special emphasis to industrially relevant applications of hybrid RANS-LES methods and other turbulence-resolving modelling approaches. The book addresses academic researchers, graduate students, industrial engineers, as well as industrial R&D managers and consultants dealing with turbulence modelling, simulation and measurement, and with multidisciplinary applications of computational fluid dynamics (CFD), such as flow control, aero-acoustics, aero-elasticity and CFD-based multidisciplinary optimization. It discusses in particular advanced hybrid RANS-LES methods. Further topics include wall-modelled Large Eddy Simulation (WMLES) methods, embedded LES, and a comparison of the LES methods with both hybrid RANS-LES and URANS methods. ...

  7. RanBPM, a scaffolding protein for gametogenesis.

    Science.gov (United States)

    Puverel, Sandrine; Tessarollo, Lino

    2013-01-01

    RanBPM is a multimodular scaffold protein that interacts with a great variety of molecules including nuclear, cytoplasmic, and membrane proteins. By building multiprotein complexes, RanBPM is thought to regulate various signaling pathways, especially in the immune and nervous system. However, the diversity of these interactions does not facilitate the identification of its precise mechanism of action, and therefore the physiological role of RanBPM still remains unclear. Recently, RanBPM has been shown to be critical for the fertility of both genders in mouse. Although mechanistically it is still unclear how RanBPM affects gametogenesis, the data collected so far suggest that it is a key player in this process. Here, we examine the RanBPM sterility phenotype in the context of other genetic mutations affecting mouse gametogenesis to investigate whether this scaffold protein affects the function of other known proteins whose deficiency results in similar sterility phenotypes. Copyright © 2013 Elsevier Inc. All rights reserved.

  8. Characterization of spectral responses of dissolved organic matter (DOM) for atrazine binding during the sorption process onto black soil.

    Science.gov (United States)

    Wang, Yifan; Zhang, Xinyuan; Zhang, Xing; Meng, Qingjuan; Gao, Fengjie; Zhang, Ying

    2017-08-01

    This study was aim to investigate the interaction between soil-derived dissolved organic matter (DOM) and atrazine as a kind of pesticides during the sorption process onto black soil. According to the experimental data, the adsorption capacity of Soil + DOM, Soil and DOM were 41.80, 31.45 and 9.35 mg kg(-1), separately, which indicated that DOM significantly enhanced the adsorption efficiency of atrazine by soil. Data implied that the pseudo-second-order kinetic equation could well explain the adsorption process. The adsorption isotherms (R(2) > 0.99) had a satisfactory fit in both Langmuir and Freundlich models. Three-dimensional excitation-emission matrix (3D-EEM), synchronous fluorescence, two-dimensional correlation spectroscopy (2D-COS) and Fourier transform infrared spectroscopy (FT-IR) were selected to analyze the interaction between DOM and atrazine. 3D-EEM showed that humic acid-like substances were the main component of DOM. The fluorescence of DOM samples were gradually quenched with the increased of atrazine concentrations. Synchronous fluorescence spectra showed that static fluorescence quenching was the main quenching process. 2D-COS indicated that the order of the spectral changes were as following: 336 nm > 282 nm. Furthermore, the fluorescence quenching of humic-like fraction occurred earlier than that of protein-like fraction under atrazine surroundings. FT-IR spectra indicated that main compositions of soil DOM include proteins, polysaccharides and humic substances. The findings of this study are significant to reveal DOM played an important role in the environmental fate of pesticides during sorption process onto black soil and also provide more useful information for understanding the interaction between DOM and pesticides by using spectral responses. Copyright © 2017. Published by Elsevier Ltd.

  9. Assessment of 3D-RANS models for the simulation of topographically forced shallow flows

    Directory of Open Access Journals (Sweden)

    Safarzadeh Akbar

    2016-03-01

    Full Text Available In this work the performance of Reynolds Averaged Navier-Stokes (RANS simulations to predict the flow structure developed by the presence of a sidewall obstacle in a uniform open-channel shallow flow is discussed. The tested geometry was selected due to its important role in several fluvial applications, such as the control of riverbank erosion and the creation of improved ecological conditions in river restoration applications. The results are compared against experimental laboratory velocity fields obtained after Large Scale Particle Image Velocimetry (LSPIV measurements. It is shown that the length of reattachment of the separated shear layer generated by the obstacle is well predicted by a Reynolds Stress Model, while classical two-equation models show important limitations. All the performed RANS simulations are unable to properly predict the formation of a secondary gyre region, which develops immediately downstream the obstacle.

  10. "Baltiiski dom 2008" : uvelitshitelnoje steklo / Eteri Kekelidze

    Index Scriptorium Estoniae

    Kekelidze, Eteri, 1944-

    2008-01-01

    Peterburis toimunud kaheksteistkümnenda rahvusvahelise teatrifestivali "Baltiiski dom" lavastustest - Kristian Smedsi "Tundmatu sõdur", Alvis Hermanise "Läti rong", Luk Percevali "Kaubareisija surm", Igor Konjajevi "Matke mind põrandaliistu taha" ja Andrzej Bubeni "Vene moos". Ka teater NO99 osalemisest Tiit Ojasoo lavastusega "GEP"

  11. Interactions between copper(II) and DOM in the urban stormwater runoff: modeling and characterizations.

    Science.gov (United States)

    Zhao, Chen; Wang, Chong-Chen; Li, Jun-Qi; Wang, Peng; Ou, Jia-Qi; Cui, Jing-Rui

    2018-01-01

    Dissolved organic matter (DOM) can strongly interact with both organic and inorganic contaminants to influence their transportation, transformation, bioavailability, toxicity and even their ultimate fate. Within this work, DOM was extracted from urban stormwater runoff samples collected from a regular sampling site of a typical residential area in Beijing, China. Copper(II) ions were selected as model to investigate the interactions between DOM and typical heavy metals. Both ultraviolet (UV) absorbance and fluorescence titration methods were introduced to determine the complex capacities (CL) and conditional stability constants (log KM) of bonding between DOM and copper (II) ions, which revealed that the values of CL were 85.62 and 87.23 μmol mg-1 and the log KM values were 5.37 and 5.48, respectively. The results suggested the successful complexation between DOM and copper(II) ions. Furthermore, morphology of the DOM binding to copper(II) ions was confirmed by both energy-dispersive X-ray spectroscopy (EDX) and X-ray photoelectron spectroscopy (XPS), which can facilitate to clarify the corresponding mechanism. The Cu 2p3/2 peak at 933.7 eV and the characteristic shake-up peaks of Cu-O were found in the XPS spectra, implying that copper(II) ions might coordinate with hydroxyl (aliphatic or phenolic) or carboxyl groups. With these profitable results, it can be concluded that DOM in urban stormwater runoff has a strong binding affinity with copper(II) ions, which may further lead to potentially significant influence on their migration and transformation.

  12. Molecular characterization of dissolved organic matter (DOM) in seawater

    NARCIS (Netherlands)

    van Heemst, J.D.H.

    2000-01-01

    Dissolved organic matter (DOM) plays an important role in the global carbon cycle (chapter 1). However, not much is known about the molecular composition and the origin of DOM. The study described in this thesis was conducted to gain more knowledge on the molecular composition and the origin of DOM.

  13. Antisense expression of an Arabidopsis ran binding protein renders transgenic roots hypersensitive to auxin and alters auxin-induced root growth and development by arresting mitotic progress

    Science.gov (United States)

    Kim, S. H.; Arnold, D.; Lloyd, A.; Roux, S. J.

    2001-01-01

    We cloned a cDNA encoding an Arabidopsis Ran binding protein, AtRanBP1c, and generated transgenic Arabidopsis expressing the antisense strand of the AtRanBP1c gene to understand the in vivo functions of the Ran/RanBP signal pathway. The transgenic plants showed enhanced primary root growth but suppressed growth of lateral roots. Auxin significantly increased lateral root initiation and inhibited primary root growth in the transformants at 10 pM, several orders of magnitude lower than required to induce these responses in wild-type roots. This induction was followed by a blockage of mitosis in both newly emerged lateral roots and in the primary root, ultimately resulting in the selective death of cells in the tips of both lateral and primary roots. Given the established role of Ran binding proteins in the transport of proteins into the nucleus, these findings are consistent with a model in which AtRanBP1c plays a key role in the nuclear delivery of proteins that suppress auxin action and that regulate mitotic progress in root tips.

  14. Are Discrepancies in RANS Modeled Reynolds Stresses Random?

    CERN Document Server

    Xiao, Heng; Wang, Jian-xun; Paterson, Eric G

    2016-01-01

    In the turbulence modeling community, significant efforts have been made to quantify the uncertainties in the Reynolds-Averaged Navier--Stokes (RANS) models and to improve their predictive capabilities. Of crucial importance in these efforts is the understanding of the discrepancies in the RANS modeled Reynolds stresses. However, to what extent these discrepancies can be predicted or whether they are completely random remains a fundamental open question. In this work we used a machine learning algorithm based on random forest regression to predict the discrepancies. The success of the regression--prediction procedure indicates that, to a large extent, the discrepancies in the modeled Reynolds stresses can be explained by the mean flow feature, and thus they are universal quantities that can be extrapolated from one flow to another, at least among different flows sharing the same characteristics such as separation. This finding has profound implications to the future development of RANS models, opening up new ...

  15. Progress in Hybrid RANS-LES Modelling : Papers Contributed to the 4th Symposium on Hybrid RANS-LES Methods

    CERN Document Server

    Haase, Werner; Peng, Shia-Hui; Schwamborn, Dieter

    2013-01-01

    The present book contains contributions presented at the Fourth Symposium on Hybrid RANS-LES Methods, held in Beijing, China, 28-30 September 2011, being a continuation of symposia taking place in Stockholm (Sweden, 2005), in Corfu (Greece, 2007), and Gdansk (Poland, 2009). The contributions to the last two symposia were published as NNFM, Vol. 97 and Vol. 111. At the Beijing symposium, along with seven invited keynotes, another 46 papers (plus 5 posters) were presented addressing topics on Novel turbulence-resolving simulation and modelling, Improved hybrid RANS-LES methods, Comparative studies of difference modelling methods, Modelling-related numerical issues and Industrial applications.. The present book reflects recent activities and new progress made in the development and applications of hybrid RANS-LES methods in general.

  16. Marginalia: algumas notas adicionais sobre o dom

    OpenAIRE

    Bourdieu, Pierre

    1996-01-01

    Prosseguindo a análise do dom, este artigo busca ultrapassar as visões fenomenológica, estruturalista e economicista do fenômeno. Para tanto, desloca o eixo de interrogação na direção do tempo e da incerteza ligados ao intervalo entre o dom e o contradom, do agente e da ação ligados às práticas, da economia de bens simbólicos e o habitus específico que a funda. Demonstrase assim, contra todo reducionismo (à consciência, ao cálculo inconsciente ou ao cálculo propriamente dito), que a razão do ...

  17. Cloud RAN for Mobile Networks - a Technology Overview

    DEFF Research Database (Denmark)

    Checko, Aleksandra; Christiansen, Henrik Lehrmann; Yan, Ying

    2014-01-01

    Pool for statistical multiplexing gain, while shifting the burden to the high-speed wireline transmission of In-phase and Quadrature (IQ) data. C-RAN enables energy efficient network operation and possible cost savings on base- band resources. Furthermore, it improves network capacity by performing...

  18. Envisioning Spectrum Management in Virtualised C-RAN

    DEFF Research Database (Denmark)

    Al-Samman, Imad; Artuso, Matteo; Christiansen, Henrik Lehrmann

    2017-01-01

    Cloud Radio Access Network (C-RAN) has attracted a worldwide attention in both academia and industry. This network architecture re-forming has been considered as a potential solution to meet the increasing capacity demands for future mobile data traffic. In addition, Network Virtualisation is a p...

  19. Hybrid RANS-LES using high order numerical methods

    Science.gov (United States)

    Henry de Frahan, Marc; Yellapantula, Shashank; Vijayakumar, Ganesh; Knaus, Robert; Sprague, Michael

    2017-11-01

    Understanding the impact of wind turbine wake dynamics on downstream turbines is particularly important for the design of efficient wind farms. Due to their tractable computational cost, hybrid RANS/LES models are an attractive framework for simulating separation flows such as the wake dynamics behind a wind turbine. High-order numerical methods can be computationally efficient and provide increased accuracy in simulating complex flows. In the context of LES, high-order numerical methods have shown some success in predictions of turbulent flows. However, the specifics of hybrid RANS-LES models, including the transition region between both modeling frameworks, pose unique challenges for high-order numerical methods. In this work, we study the effect of increasing the order of accuracy of the numerical scheme in simulations of canonical turbulent flows using RANS, LES, and hybrid RANS-LES models. We describe the interactions between filtering, model transition, and order of accuracy and their effect on turbulence quantities such as kinetic energy spectra, boundary layer evolution, and dissipation rate. This work was funded by the U.S. Department of Energy, Exascale Computing Project, under Contract No. DE-AC36-08-GO28308 with the National Renewable Energy Laboratory.

  20. Eye-Movement Control in RAN and Reading

    Science.gov (United States)

    Kuperman, Victor; Van Dyke, Julie A.; Henry, Regina

    2016-01-01

    The present study examined the "visual scanning hypothesis", which suggests that fluent oculomotor control is an important component underlying the predictive relationship between Rapid Automatized Naming (RAN) tasks and reading ability. Our approach was to isolate components of saccadic planning, articulation, and lexical retrieval in 3…

  1. HIV Integration Targeting: A Pathway Involving Transportin-3 and the Nuclear Pore Protein RanBP2

    Science.gov (United States)

    Huegel, Alyssa; Roth, Shoshannah L.; Schaller, Torsten; James, Leo C.; Towers, Greg J.; Young, John A. T.; Chanda, Sumit K.; König, Renate; Malani, Nirav; Berry, Charles C.; Bushman, Frederic D.

    2011-01-01

    Genome-wide siRNA screens have identified host cell factors important for efficient HIV infection, among which are nuclear pore proteins such as RanBP2/Nup358 and the karyopherin Transportin-3/TNPO3. Analysis of the roles of these proteins in the HIV replication cycle suggested that correct trafficking through the pore may facilitate the subsequent integration step. Here we present data for coupling between these steps by demonstrating that depletion of Transportin-3 or RanBP2 altered the terminal step in early HIV replication, the selection of chromosomal sites for integration. We found that depletion of Transportin-3 and RanBP2 altered integration targeting for HIV. These knockdowns reduced HIV integration frequency in gene-dense regions and near gene-associated features, a pattern that differed from that reported for depletion of the HIV integrase binding cofactor Psip1/Ledgf/p75. MLV integration was not affected by the Transportin-3 knockdown. Using siRNA knockdowns and integration targeting analysis, we also implicated several additional nuclear proteins in proper target site selection. To map viral determinants of integration targeting, we analyzed a chimeric HIV derivative containing MLV gag, and found that the gag replacement phenocopied the Transportin-3 and RanBP2 knockdowns. Thus, our data support a model in which Gag-dependent engagement of the proper transport and nuclear pore machinery mediate trafficking of HIV complexes to sites of integration. PMID:21423673

  2. HIV integration targeting: a pathway involving Transportin-3 and the nuclear pore protein RanBP2.

    Directory of Open Access Journals (Sweden)

    Karen E Ocwieja

    2011-03-01

    Full Text Available Genome-wide siRNA screens have identified host cell factors important for efficient HIV infection, among which are nuclear pore proteins such as RanBP2/Nup358 and the karyopherin Transportin-3/TNPO3. Analysis of the roles of these proteins in the HIV replication cycle suggested that correct trafficking through the pore may facilitate the subsequent integration step. Here we present data for coupling between these steps by demonstrating that depletion of Transportin-3 or RanBP2 altered the terminal step in early HIV replication, the selection of chromosomal sites for integration. We found that depletion of Transportin-3 and RanBP2 altered integration targeting for HIV. These knockdowns reduced HIV integration frequency in gene-dense regions and near gene-associated features, a pattern that differed from that reported for depletion of the HIV integrase binding cofactor Psip1/Ledgf/p75. MLV integration was not affected by the Transportin-3 knockdown. Using siRNA knockdowns and integration targeting analysis, we also implicated several additional nuclear proteins in proper target site selection. To map viral determinants of integration targeting, we analyzed a chimeric HIV derivative containing MLV gag, and found that the gag replacement phenocopied the Transportin-3 and RanBP2 knockdowns. Thus, our data support a model in which Gag-dependent engagement of the proper transport and nuclear pore machinery mediate trafficking of HIV complexes to sites of integration.

  3. Characterization of RanBPM Molecular Determinants that Control Its Subcellular Localization

    Science.gov (United States)

    Salemi, Louisa M.; Loureiro, Sandra O.; Schild-Poulter, Caroline

    2015-01-01

    RanBPM/RanBP9 is a ubiquitous, nucleocytoplasmic protein that is part of an evolutionary conserved E3 ubiquitin ligase complex whose function and targets in mammals are still unknown. RanBPM itself has been implicated in various cellular processes that involve both nuclear and cytoplasmic functions. However, to date, little is known about how RanBPM subcellular localization is regulated. We have conducted a systematic analysis of RanBPM regions that control its subcellular localization using RanBPM shRNA cells to examine ectopic RanBPM mutant subcellular localization without interference from the endogenously expressed protein. We show that several domains and motifs regulate RanBPM nuclear and cytoplasmic localization. In particular, RanBPM comprises two motifs that can confer nuclear localization, one proline/glutamine-rich motif in the extreme N-terminus which has a dominant effect on RanBPM localization, and a second motif in the C-terminus which minimally contributes to RanBPM nuclear targeting. We also identified a nuclear export signal (NES) which mutation prevented RanBPM accumulation in the cytoplasm. Likewise, deletion of the central RanBPM conserved domains (SPRY and LisH/CTLH) resulted in the relocalization of RanBPM to the nucleus, suggesting that RanBPM cytoplasmic localization is also conferred by protein-protein interactions that promote its cytoplasmic retention. Indeed we found that in the cytoplasm, RanBPM partially colocalizes with microtubules and associates with α-tubulin. Finally, in the nucleus, a significant fraction of RanBPM is associated with chromatin. Altogether, these analyses reveal that RanBPM subcellular localization results from the combined effects of several elements that either confer direct transport through the nucleocytoplasmic transport machinery or regulate it indirectly, likely through interactions with other proteins and by intramolecular folding. PMID:25659156

  4. Marginalia: algumas notas adicionais sobre o dom

    Directory of Open Access Journals (Sweden)

    Pierre Bourdieu

    1996-10-01

    Full Text Available Prosseguindo a análise do dom, este artigo busca ultrapassar as visões fenomenológica, estruturalista e economicista do fenômeno. Para tanto, desloca o eixo de interrogação na direção do tempo e da incerteza ligados ao intervalo entre o dom e o contradom, do agente e da ação ligados às práticas, da economia de bens simbólicos e o habitus específico que a funda. Demonstrase assim, contra todo reducionismo (à consciência, ao cálculo inconsciente ou ao cálculo propriamente dito, que a razão do dom só pode repousar sobre sua dupla verdade, seu caráter generoso e obrigatório. Por outro lado, demonstrase também que foi somente através de uma revolução simbólica, e não o desenvolvimento de uma suposta natureza humana, que uma economia da troca pôde, historicamente, se destacar da economia do dom, cuja possibilidade continua aberta, dependendo apenas dos investimentos coletivos que sejam efetuados em sua direção.Resuming an analysis of the gift, this article seeks to go beyond the phenomenological, structuralist, and economicist view of this phenomenon. It thereby shifts the trust of questioning towards the time and uncertainty linked with the interval between the gift and the counter-gift, the agent and the action linked to such practices, the economy of symbolic goods, and the specific habitus underlying it. It thus demonstrates against any and all reductionism (to consciousness, to unconcious calculation, and to calculation per se that the gift's reason can only lie in its double truth, its generous and obligatory nature, both disinterested and interested. The author also demonstrates historically that it is only through a symbolic revolution, and not the development of a supposed human nature, that an economy of exchange can stand out from the economy of the gift, whose possibility remains open, requiring collective investments in its direction.

  5. AVHRR GAC SST Reanalysis Version 1 (RAN1

    Directory of Open Access Journals (Sweden)

    Alexander Ignatov

    2016-04-01

    Full Text Available In response to its users’ needs, the National Oceanic and Atmospheric Administration (NOAA initiated reanalysis (RAN of the Advanced Very High Resolution Radiometer (AVHRR Global Area Coverage (GAC; 4 km sea surface temperature (SST data employing its Advanced Clear Sky Processor for Oceans (ACSPO retrieval system. Initially, AVHRR/3 data from five NOAA and two Metop satellites from 2002 to 2015 have been reprocessed. The derived SSTs have been matched up with two reference SSTs—the quality controlled in situ SSTs from the NOAA in situ Quality Monitor (iQuam and the Canadian Meteorological Centre (CMC L4 SST analysis—and analyzed in the NOAA SST Quality Monitor (SQUAM online system. The corresponding clear-sky ocean brightness temperatures (BT in AVHRR bands 3b, 4 and 5 (centered at 3.7, 11, and 12 µm, respectively have been compared with the Community Radiative Transfer Model simulations in another NOAA online system, Monitoring of Infrared Clear-sky Radiances over Ocean for SST (MICROS. For some AVHRRs, the time series of “AVHRR minus reference” SSTs and “observed minus model” BTs are unstable and inconsistent, with artifacts in the SSTs and BTs strongly correlated. In the official “Reanalysis version 1” (RAN1, data from only five platforms—two midmorning (NOAA-17 and Metop-A and three afternoon (NOAA-16, -18 and -19—were included during the most stable periods of their operations. The stability of the SST time series was further improved using variable regression SST coefficients, similarly to how it was done in the NOAA/NASA Pathfinder version 5.2 (PFV5.2 dataset. For data assimilation applications, especially those blending satellite and in situ SSTs, we recommend bias-correcting the RAN1 SSTs using the newly developed sensor-specific error statistics (SSES, which are reported in the product files. Relative performance of RAN1 and PFV5.2 SSTs is discussed. Work is underway to improve the calibration of AVHRR/3s and

  6. Understanding microbial/DOM interactions using fluorescence and flow cytometry

    Science.gov (United States)

    Fox, Bethany; Rushworth, Cathy; Attridge, John; Anesio, Alexandre; Cox, Tim; Reynolds, Darren

    2015-04-01

    The transformation and movement of dissolved organic carbon (DOC) within freshwater aquatic systems is an important factor in the global cycling of carbon. DOC within aquatic systems is known to underpin the microbial food web and therefore plays an essential role in supporting and maintaining the aquatic ecosystem. Despite this the interactions between bacteria and dissolved organic matter (DOM) are not well understood, although the literature indicates that the microbial processing of bioavailable DOM is essential during the production of autochthonous, labile, DOM. DOM can be broadly characterised by its fluorescing properties and Coble et al. (2014) define terrestrially derived DOM as exhibiting "peak C" fluorescence, whilst labile microbially derived DOM is defined as showing "peak T" fluorescence. Our work explores the microbial/DOM interactions by analysing aquatic samples using fluorescence excitation and emission matrices (EEMs) in conjunction with microbial consumption of dissolved oxygen. Environmental and synthetic water samples were subjected to fluorescence characterisation using both fluorescence spectroscopy and in situ fluorescence sensors (Chelsea Technologies Group Ltd.). PARAFAC analysis and peak picking were performed on EEMs and compared with flow cytometry data, used to quantify bacterial numbers present within samples. Synthetic samples were created using glucose, glutamic acid, nutrient-rich water and a standard bacterial seed. Synthetic samples were provided with terrestrially derived DOM via the addition of an aliquot of environmental water. Using a closed system approach, samples were incubated over time (up to a maximum of 20 days) and analysed at pre-defined intervals. The main focus of our work is to improve our understanding of microbial/DOM interactions and how these interactions affect both the DOM characteristics and microbial food web in freshwater aquatic systems. The information gained, in relation to the origin, microbial

  7. GAP Activity, but Not Subcellular Targeting, Is Required for Arabidopsis RanGAP Cellular and Developmental Functions.

    Science.gov (United States)

    Boruc, Joanna; Griffis, Anna H N; Rodrigo-Peiris, Thushani; Zhou, Xiao; Tilford, Bailey; Van Damme, Daniël; Meier, Iris

    2015-07-01

    The Ran GTPase activating protein (RanGAP) is important to Ran signaling involved in nucleocytoplasmic transport, spindle organization, and postmitotic nuclear assembly. Unlike vertebrate and yeast RanGAP, plant RanGAP has an N-terminal WPP domain, required for nuclear envelope association and several mitotic locations of Arabidopsis thaliana RanGAP1. A double null mutant of the two Arabidopsis RanGAP homologs is gametophyte lethal. Here, we created a series of mutants with various reductions in RanGAP levels by combining a RanGAP1 null allele with different RanGAP2 alleles. As RanGAP level decreases, the severity of developmental phenotypes increases, but nuclear import is unaffected. To dissect whether the GAP activity and/or the subcellular localization of RanGAP are responsible for the observed phenotypes, this series of rangap mutants were transformed with RanGAP1 variants carrying point mutations abolishing the GAP activity and/or the WPP-dependent subcellular localization. The data show that plant development is differentially affected by RanGAP mutant allele combinations of increasing severity and requires the GAP activity of RanGAP, while the subcellular positioning of RanGAP is dispensable. In addition, our results indicate that nucleocytoplasmic trafficking can tolerate both partial depletion of RanGAP and delocalization of RanGAP from the nuclear envelope. © 2015 American Society of Plant Biologists. All rights reserved.

  8. Molecular characterization of dissolved organic matter (DOM) in seawater

    NARCIS (Netherlands)

    Heemst, J.D.H. van

    2000-01-01

    Dissolved organic matter (DOM) plays an important role in the global carbon cycle (chapter 1). However, not much is known about the molecular composition and the origin of DOM. The study described in this thesis was conducted to gain more knowledge on the molecular composition and the origin of

  9. En problematisk Strasbourg-dom om beskyttelse af trossamfund

    DEFF Research Database (Denmark)

    Rytter, Jens Elo

    2016-01-01

    Artiklen analyserer og kritiserer Menneskerettighedsdomstolens dom i sagen Magyar Kereztény Mennonita Egyház v. Hungary.......Artiklen analyserer og kritiserer Menneskerettighedsdomstolens dom i sagen Magyar Kereztény Mennonita Egyház v. Hungary....

  10. Dom34 Rescues Ribosomes in 3´ Untranslated Regions

    Science.gov (United States)

    Guydosh, Nicholas R.; Green, Rachel

    2014-01-01

    SUMMARY Ribosomes that stall before completing peptide synthesis must be recycled and returned to the cytoplasmic pool. The protein Dom34 and cofactors Hbs1 and Rli1 can dissociate stalled ribosomes in vitro, but the identity of targets in the cell is unknown. Here we extend ribosome profiling methodology to reveal a high-resolution molecular characterization of Dom34 function in vivo. Dom34 removes stalled ribosomes from truncated mRNAs, but, in contrast, does not generally dissociate ribosomes on coding sequences known to trigger stalling, such as polyproline. We also show that Dom34 targets arrested ribosomes near the ends of 3´ UTRs. These ribosomes appear to gain access to the 3 UTR via a mechanism that does not require decoding of the mRNA. These results suggest that ribosomes frequently enter downstream noncoding regions and that Dom34 carries out the important task of rescuing them. PMID:24581494

  11. Entrevista a Doménico Chiappe

    Directory of Open Access Journals (Sweden)

    Nohelia Meza

    2016-09-01

    Full Text Available http://dx.doi.org/10.5007/1807-9288.2016v12n1p134 En esta entrevista, Doménico Chiappe nos habla de la estructura de sus obras, de la experiencia de narrar hilando diferentes lenguajes. El autor hace énfasis en la fusión de diversas artes en las obras multimedia y subraya la necesaria convergencia de distintos artistas para su elaboración. Chiappe profundiza en los términos: brevedad, circularidad, fragmentación, hiperfonía y retórica multimedia, al mismo tiempo que nos explica cómo estos afectan tanto el proceso creativo como las diferentes formas de lectura que de él se originan.

  12. Hybrid RANS/LES applied to complex terrain

    DEFF Research Database (Denmark)

    Bechmann, Andreas; Sørensen, Niels N.

    2011-01-01

    Large Eddy Simulation (LES) of the wind in complex terrain is limited by computational cost. The number of computational grid points required to resolve the near-ground turbulent structures (eddies) are very high. The traditional solution to the problem has been to apply a wall function...... aspect ratio in the RANS layer and thereby resolve the mean near-wall velocity profile. The method is applicable to complex terrain and the benefits of traditional LES are kept intact. Using the hybrid method, simulations of the wind over a natural complex terrain near Wellington in New Zealand...

  13. Viviendas inteligentes (Domótica

    Directory of Open Access Journals (Sweden)

    Luis Felipe Herrera Quintero

    2005-05-01

    Full Text Available En los últimos años el avance de las telecomunicaciones a través de internet permite hablar de integración a nivel de redes IP (Internet Protocol. Numerosas redes funcionan con éxito y han sido fundamentales para las diversas áreas en la medida en que la automatización de los datos permiten a investigadores y profesionales tener una visión más amplia de la producción en los más variados sectores. Desde hace mucho tiempo el control a distancia viene desarrollándose gracias a la innovación tecnológica con que se cuenta hoy en día, y con ello se van haciendo tangibles cada vez más entornos de interacción humana basados en sistemas de telecomunicaciones y control. Gracias a este desarrollo tecnológico que se presenta, se produce el solo hecho de pensar en controlar remotamente dispositivos que existen en nuestro diario vivir. Según estas nuevas actividades que pueden ser realizadas por el hombre dentro de una vivienda, como por ejemplo controlar la intensidad de iluminación desde una PDA (Asistente Personal Digital son enmarcadas dentro de una nueva área del conocimiento denominada domótica. Cuando se menciona la palabra domótica se hace referencia a la integración de las diversas áreas del conocimiento como lo son las telecomunicaciones, la electrónica, la informática y la electricidad para mejorar la calidad de vida de los seres humanos, agregando con ello pautas para el acrecentar de la sociedad colombiana.

  14. Performance evaluation of RANS-based turbulence models in simulating a honeycomb heat sink

    Science.gov (United States)

    Subasi, Abdussamet; Ozsipahi, Mustafa; Sahin, Bayram; Gunes, Hasan

    2017-07-01

    As well-known, there is not a universal turbulence model that can be used to model all engineering problems. There are specific applications for each turbulence model that make it appropriate to use, and it is vital to select an appropriate model and wall function combination that matches the physics of the problem considered. Therefore, in this study, performance of six well-known Reynolds-Averaged Navier-Stokes ( RANS) based turbulence models which are the Standard k {{-}} ɛ, the Renormalized Group k- ɛ, the Realizable k- ɛ, the Reynolds Stress Model, the k- ω and the Shear Stress Transport k- ω and accompanying wall functions which are the standard, the non-equilibrium and the enhanced are evaluated via 3D simulation of a honeycomb heat sink. The CutCell method is used to generate grid for the part including heat sink called test section while a hexahedral mesh is employed to discretize to inlet and outlet sections. A grid convergence study is conducted for verification process while experimental data and well-known correlations are used to validate the numerical results. Prediction of pressure drop along the test section, mean base plate temperature of the heat sink and temperature at the test section outlet are regarded as a measure of the performance of employed models and wall functions. The results indicate that selection of turbulence models and wall functions has a great influence on the results and, therefore, need to be selected carefully. Hydraulic and thermal characteristics of the honeycomb heat sink can be determined in a reasonable accuracy using RANS- based turbulence models provided that a suitable turbulence model and wall function combination is selected.

  15. Aggresome formation is regulated by RanBPM through an interaction with HDAC6

    Directory of Open Access Journals (Sweden)

    Louisa M. Salemi

    2014-05-01

    Full Text Available In conditions of proteasomal impairment, the build-up of damaged or misfolded proteins activates a cellular response leading to the recruitment of damaged proteins into perinuclear aggregates called aggresomes. Aggresome formation involves the retrograde transport of cargo proteins along the microtubule network and is dependent on the histone deacetylase HDAC6. Here we show that ionizing radiation (IR promotes Ran-Binding Protein M (RanBPM relocalization into discrete perinuclear foci where it co-localizes with aggresome components ubiquitin, dynein and HDAC6, suggesting that the RanBPM perinuclear clusters correspond to aggresomes. RanBPM was also recruited to aggresomes following treatment with the proteasome inhibitor MG132 and the DNA-damaging agent etoposide. Strikingly, aggresome formation by HDAC6 was markedly impaired in RanBPM shRNA cells, but was restored by re-expression of RanBPM. RanBPM was found to interact with HDAC6 and to inhibit its deacetylase activity. This interaction was abrogated by a RanBPM deletion of its LisH/CTLH domain, which also prevented aggresome formation, suggesting that RanBPM promotes aggresome formation through an association with HDAC6. Our results suggest that RanBPM regulates HDAC6 activity and is a central regulator of aggresome formation.

  16. Preferential remineralization of dissolved organic phosphorus and non-Redfield DOM dynamics in the global ocean: Impacts on marine productivity, nitrogen fixation, and carbon export

    Science.gov (United States)

    Letscher, Robert T.; Moore, J. Keith

    2015-03-01

    Selective removal of nitrogen (N) and phosphorus (P) from the marine dissolved organic matter (DOM) pool has been reported in several regional studies. Because DOM is an important advective/mixing pathway of carbon (C) export from the ocean surface layer and its non-Redfieldian stoichiometry would affect estimates of marine export production per unit N and P, we investigated the stoichiometry of marine DOM and its remineralization globally using a compiled DOM data set. Marine DOM is enriched in C and N compared to Redfield stoichiometry, averaging 317:39:1 and 810:48:1 for C:N:P within the degradable and total bulk pools, respectively. Dissolved organic phosphorus (DOP) is found to be preferentially remineralized about twice as rapidly with respect to the enriched C:N stoichiometry of marine DOM. Biogeochemical simulations with the Biogeochemical Elemental Cycling model using Redfield and variable DOM stoichiometry corroborate the need for non-Redfield dynamics to match the observed DOM stoichiometry. From our model simulations, preferential DOP remineralization is found to increase the strength of the biological pump by ~9% versus the case of Redfield DOM cycling. Global net primary productivity increases ~10% including an increase in marine nitrogen fixation of ~26% when preferential DOP remineralization and direct utilization of DOP by phytoplankton are included. The largest increases in marine nitrogen fixation, net primary productivity, and carbon export are observed within the western subtropical gyres, suggesting the lateral transfer of P in the form of DOP from the productive eastern and poleward gyre margins may be important for sustaining these processes downstream in the subtropical gyres.

  17. A Taylor-Microscale Transport Model for RANS

    Science.gov (United States)

    Israel, Daniel; Hsu, Abigail; Rudolph, Joshua

    2017-11-01

    Since the first development of complete two-equation RANS models, there have been a variety of proposals for the choice of a second scaling quantity. Some of the most popular have been a time-scale ω (Kolmogorov, 1942; Wilcox, 1998), the dissipation rate ɛ (Harlow et al., 1968), the integral length-scale L, and the product kl (Mellor et al., 1982). All of these are formally equivalent in the production and dissipation terms, and differ only in which quantity is turbulently diffused. They also all rely on an equilibrium assumption that links the dissipation rate at the small scales to the scale of the large eddies. We propose using the Taylor microscale as the second scale. This has several nice properties, and also exhibits some interesting mathematical differences from conventional models. We show results for some simple shear flows using the new model.

  18. “Wrapping” X3DOM around Web Audio API

    Directory of Open Access Journals (Sweden)

    Andreas Stamoulias

    2015-12-01

    Full Text Available Spatial sound has a conceptual role in the Web3D environments, due to highly realism scenes that can provide. Lately the efforts are concentrated on the extension of the X3D/ X3DOM through spatial sound attributes. This paper presents a novel method for the introduction of spatial sound components in the X3DOM framework, based on X3D specification and Web Audio API. The proposed method incorporates the introduction of enhanced sound nodes for X3DOM which are derived by the implementation of the X3D standard components, enriched with accessional features of Web Audio API. Moreover, several examples-scenarios developed for the evaluation of our approach. The implemented examples established the achievability of new registered nodes in X3DOM, for spatial sound characteristics in Web3D virtual worlds.

  19. Vse dorogi vedut v "Baltiiski dom" / Svetlana Jantshek

    Index Scriptorium Estoniae

    Jantshek, Svetlana

    2000-01-01

    3.-9. apr. korraldas "Baltiiski Dom" SRÜ ja Baltimaade vene teatrite teise festivali, millest võttis osa ka Vene Draamateater kahe lavastusega - Jaan Tätte "Ristumine peateega" ja S. Mrozheki "Emigrandid"

  20. How Is RAN Related to Reading Fluency? A Comprehensive Examination of the Prominent Theoretical Accounts

    Science.gov (United States)

    Papadopoulos, Timothy C.; Spanoudis, George C.; Georgiou, George K.

    2016-01-01

    We examined the prominent theoretical explanations of the RAN-reading relationship in a relatively transparent language (Greek) in a sample of children (n = 286) followed from Grade 1 to Grade 2. Specifically, we tested the fit of eight different models, as defined by the type of reading performance predicted (oral vs. silent word reading fluency), the type of RAN tasks (non-alphanumeric vs. alphanumeric), and the RAN effects (direct vs. indirect). Working memory, attention, processing speed, and motor skills were used as “common cause” variables predicting both RAN and reading fluency and phonological awareness and orthographic processing were used as mediators of RAN's effects on reading fluency. The findings of both concurrent and longitudinal analyses indicated that RAN is a unique predictor of oral reading fluency, but not silent reading fluency. Using alphanumeric or non-alphanumeric RAN did not particularly affect the RAN-reading relationship. Both phonological awareness and orthographic processing partly mediated RAN's effects on reading fluency. Theoretical implications of these findings are discussed. PMID:27605918

  1. Encephalomyocarditis virus Leader protein hinge domain is responsible for interactions with Ran GTPase

    Energy Technology Data Exchange (ETDEWEB)

    Bacot-Davis, Valjean R., E-mail: bacotdavis@wisc.edu [Institute for Molecular Virology, University of Wisconsin-Madison, R.M. Bock Laboratories, 1525 Linden Dr. Madison, WI 53706 (United States); Palmenberg, Ann C., E-mail: acpalmen@wisc.edu [Institute for Molecular Virology, University of Wisconsin-Madison, R.M. Bock Laboratories, 1525 Linden Dr. Madison, WI 53706 (United States); Department of Biochemistry, University of Wisconsin-Madison, R.M. Bock Laboratories, 1525 Linden Dr. Madison, WI 53706 (United States)

    2013-08-15

    Encephalomyocarditis virus (EMCV), a Cardiovirus, initiates its polyprotein with a short 67 amino acid Leader (L) sequence. The protein acts as a unique pathogenicity factor, with anti-host activities which include the triggering of nuclear pore complex hyperphosphorylation and direct binding inhibition of the active cellular transport protein, Ran GTPase. Chemical modifications and protein mutagenesis now map the Ran binding domain to the L hinge-linker region, and in particular, to amino acids 35–40. Large deletions affecting this region were shown previously to diminish Ran binding. New point mutations, especially K35Q, D37A and W40A, preserve the intact L structure, abolish Ran binding and are deficient for nucleoporin (Nup) hyperphosphorylation. Ran itself morphs through multiple configurations, but reacts most effectively with L when in the GDP format, preferably with an empty nucleotide binding pocket. Therefore, L:Ran binding, mediated by the linker-hinge, is a required step in L-induced nuclear transport inhibition. - Highlights: • The hinge domain provides critical residues in Cardiovirus L:Ran complex formation. • Leader prefers to bind Ran in a nucleotide free, GDP-conformation. • L-induced Nup62 phosphorylation is reduced with Ran-deficient binding mutations.

  2. How Is RAN Related to Reading Fluency? A Comprehensive Examination of the Prominent Theoretical Accounts.

    Science.gov (United States)

    Papadopoulos, Timothy C; Spanoudis, George C; Georgiou, George K

    2016-01-01

    We examined the prominent theoretical explanations of the RAN-reading relationship in a relatively transparent language (Greek) in a sample of children (n = 286) followed from Grade 1 to Grade 2. Specifically, we tested the fit of eight different models, as defined by the type of reading performance predicted (oral vs. silent word reading fluency), the type of RAN tasks (non-alphanumeric vs. alphanumeric), and the RAN effects (direct vs. indirect). Working memory, attention, processing speed, and motor skills were used as "common cause" variables predicting both RAN and reading fluency and phonological awareness and orthographic processing were used as mediators of RAN's effects on reading fluency. The findings of both concurrent and longitudinal analyses indicated that RAN is a unique predictor of oral reading fluency, but not silent reading fluency. Using alphanumeric or non-alphanumeric RAN did not particularly affect the RAN-reading relationship. Both phonological awareness and orthographic processing partly mediated RAN's effects on reading fluency. Theoretical implications of these findings are discussed.

  3. The cyst nematode SPRYSEC protein RBP-1 elicits Gpa2- and RanGAP2-dependent plant cell death.

    Directory of Open Access Journals (Sweden)

    Melanie Ann Sacco

    2009-08-01

    Full Text Available Plant NB-LRR proteins confer robust protection against microbes and metazoan parasites by recognizing pathogen-derived avirulence (Avr proteins that are delivered to the host cytoplasm. Microbial Avr proteins usually function as virulence factors in compatible interactions; however, little is known about the types of metazoan proteins recognized by NB-LRR proteins and their relationship with virulence. In this report, we demonstrate that the secreted protein RBP-1 from the potato cyst nematode Globodera pallida elicits defense responses, including cell death typical of a hypersensitive response (HR, through the NB-LRR protein Gpa2. Gp-Rbp-1 variants from G. pallida populations both virulent and avirulent to Gpa2 demonstrated a high degree of polymorphism, with positive selection detected at numerous sites. All Gp-RBP-1 protein variants from an avirulent population were recognized by Gpa2, whereas virulent populations possessed Gp-RBP-1 protein variants both recognized and non-recognized by Gpa2. Recognition of Gp-RBP-1 by Gpa2 correlated to a single amino acid polymorphism at position 187 in the Gp-RBP-1 SPRY domain. Gp-RBP-1 expressed from Potato virus X elicited Gpa2-mediated defenses that required Ran GTPase-activating protein 2 (RanGAP2, a protein known to interact with the Gpa2 N terminus. Tethering RanGAP2 and Gp-RBP-1 variants via fusion proteins resulted in an enhancement of Gpa2-mediated responses. However, activation of Gpa2 was still dependent on the recognition specificity conferred by amino acid 187 and the Gpa2 LRR domain. These results suggest a two-tiered process wherein RanGAP2 mediates an initial interaction with pathogen-delivered Gp-RBP-1 proteins but where the Gpa2 LRR determines which of these interactions will be productive.

  4. Adsorption and structural fractionation of dissolved organic matter (DOM) by soil mineral surfaces

    Science.gov (United States)

    Avneri, Shani; Polubesova, Tamara; Chefetz, Benny

    2015-04-01

    Dissolved organic matter (DOM) represents a small but highly reactive fraction of the soil organic matter (SOM). One of the important processes affecting the fate of DOM in soils is its interactions with mineral phases. Adsorptive fractionation of DOM by soils and minerals has been observed previously, however detailed changes in composition of DOM due to its interactions with mineral soils were not yet elucidated. In this research the adsorption and physico-chemical fractionation of DOM by soil poor with organic matter and rich with iron oxides and clay fraction was investigated. The changes in DOM structural composition were studied using separation with polymeric resins. The following fractions were obtained: hydrophobic acid (HoA), hydrophobic neutral (HoN), hydrophilic acid (HiA), hydrophilic base (HiB), and hydrophilic neutral (HiN). Two types of DOM were studied: DOM extracted from composted biosolids (compost DOM) and DOM from Suwanee River (SRNOM). Sorption affinity of DOM to soil mineral surfaces was source and chemistry dependent. SRNOM, which was characterized by higher content of aromatic and carboxylic groups demonstrated higher affinity to the studied soil than compost DOM. For both DOM samples preferential adsorption of HoA by soil (50-85% from adsorbed carbon) was observed. Desorption of both DOM types demonstrated significant hysteresis (up to 90-100% of dissolved organic carbon was retained by the soil after 3 cycles of desorption stages). This suggests that DOM desorption behavior was affected by HoA dominant adsorption to the soil mineral fraction, and not by DOM source. Results of this study indicate that interactions of different types of DOM with mineral soil may result in similar changes in composition and properties of DOM both in the supernatant as well as in the adsorbed phase. The change in DOM composition due to its interaction with soil minerals may influence the interactions of pollutants with DOM and soil particle surfaces.

  5. RAN as a predictor of reading skills, and vice versa: results from a randomised reading intervention.

    Science.gov (United States)

    Wolff, Ulrika

    2014-07-01

    Although phonemic awareness is a well-known factor predicting early reading development, there is also evidence that Rapid Automatized Naming (RAN) is an independent factor that contributes to early reading. The aim of this study is to examine phonemic awareness and RAN as predictors of reading speed, reading comprehension and spelling for children with reading difficulties. It also investigates a possible reciprocal relationship between RAN and reading skills, and the possibility of enhancing RAN by intervention. These issues are addressed by examining longitudinal data from a randomised reading intervention study carried out in Sweden for 9-year-old children with reading difficulties (N = 112). The intervention comprised three main elements: training of phonics, reading comprehension strategies and reading speed. The analysis of the data was carried out using structural equation modelling. The results demonstrated that after controlling for autoregressive effects and non-verbal IQ, RAN predicts reading speed whereas phonemic awareness predicts reading comprehension and spelling. RAN was significantly enhanced by training and a reciprocal relationship between reading speed and RAN was found. These findings contribute to support the view that both phonemic awareness and RAN independently influence early phases of reading, and that both are possible to enhance by training.

  6. RAN as a Predictor of Reading Skills, and Vice Versa: Results from a Randomised Reading Intervention

    Science.gov (United States)

    Wolff, Ulrika

    2014-01-01

    Although phonemic awareness is a well-known factor predicting early reading development, there is also evidence that Rapid Automatized Naming (RAN) is an independent factor that contributes to early reading. The aim of this study is to examine phonemic awareness and RAN as predictors of reading speed, reading comprehension and spelling for…

  7. Mesh Resolution Effect on 3D RANS Turbomachinery Flow Simulations

    CERN Document Server

    Yershov, Sergiy

    2016-01-01

    The paper presents the study of the effect of a mesh refinement on numerical results of 3D RANS computations of turbomachinery flows. The CFD solver F, which based on the second-order accurate ENO scheme, is used in this study. The simplified multigrid algorithm and local time stepping permit decreasing computational time. The flow computations are performed for a number of turbine and compressor cascades and stages. In all flow cases, the successively refined meshes of H-type with an approximate orthogonalization near the solid walls were generated. The results obtained are compared in order to estimate their both mesh convergence and ability to resolve the transonic flow pattern. It is concluded that for thorough studying the fine phenomena of the 3D turbomachinery flows, it makes sense to use the computational meshes with the number of cells from several millions up to several hundred millions per a single turbomachinery blade channel, while for industrial computations, a mesh of about or less than one mil...

  8. As vicissitudes do "ensaio sobre o dom"

    Directory of Open Access Journals (Sweden)

    Lygia Sigaud

    1999-10-01

    Full Text Available A partir dos anos 60, antropólogos de diferentes tradições nacionais passaram a convergir no sentido de considerar que o texto de Marcel Mauss, "Ensaio sobre o Dom", contivesse uma teoria da troca, que atribui à identificação entre a coisa dada e o espírito do doador o princípio de explicação das transações. Esta interpretação contrasta com a que tiveram os contemporâneos de Mauss, os quais resgataram do trabalho suas dimensões relativas ao direito, às obrigações e às prestações totais. Partindo desta constatação, o artigo problematiza o destino do ensaio e busca torná-lo inteligível. Para tanto examina as condições sociointelectuais que contribuíram para que se produzisse a inflexão na leitura e a consolidação de uma espécie de crença coletiva em relação ao trabalho. Através deste estudo de caso, a autora identifica mecanismos que operam no processo de construção de teorias, na conformação de representações acerca de textos e na sua consagração no âmbito da antropologia.From the 1960s, anthropologists of different national traditions came to share the view that Marcel Mauss’s text, "Essay on the Gift," contained a theory of exchange which takes the identification between the thing given and the spirit of the donor as the explanatory principle of transactions. This interpretation contrasts with that held by Mauss’s contemporaries, who lifted from the work aspects relating to law, obligations and total prestations. Starting from this fact, the article problematizes the essay’s fate and seeks to make it intelligible. To this end, it examines the socio-intellectual conditions which contributed to producing this inflection in the readings of the work and the consolidation of a kind of collective belief concerning it. Through this case study, the author identifies mechanisms which operate in the process of constructing theories, in the conformity found in representations of certain texts, and in the

  9. What controls DOM/POM partitioning in rivers?

    Science.gov (United States)

    Hernes, P.; Spencer, R.; Matiasek, S. J.; Dyda, R. Y.

    2016-12-01

    Dissolved and particulate organic matter (DOM and POM) in rivers are generally treated as separate pools of carbon with minimal interactions, hence infrequently studied simultaneously. While it is undoubtedly true that there are river systems in which sorption/desorption has little impact on either DOM or POM compositions, it is also undoubtedly true that partitioning is extremely important in others. For example, dissolved lignin in an agricultural catchment in California was strongly correlated to total suspended sediments, while it is well-known that organic-poor minerals eroded in the Bolivian highlands sorbs large amount of DOM upon entering the Amazon River system. This presentation will explore partitioning in rivers primarily through the lens of molecular-level lignin data. In general, POM lignin has lower acid:aldehyde ratios than DOM, lower S:V and C:V ratios, but higher carbon-normalized yields. Factors that influence the relative amount of partitioning include mineralogy, DOC:POM ratios in rivers, OM-loading of sediment entering the streams, and composition of both DOM and POM.

  10. Exploiting Statistical Methodologies and Controlled Vocabularies for Prioritized Functional Analysis of Genomic Experiments: the StRAnGER Web Application.

    Science.gov (United States)

    Chatziioannou, Aristotelis A; Moulos, Panagiotis

    2011-01-01

    StRAnGER is a web application for the automated statistical analysis of annotated gene profiling experiments, exploiting controlled biological vocabularies, like the Gene Ontology or the KEGG pathways terms. Starting from annotated lists of differentially expressed genes and gene enrichment scores, regarding the terms of each vocabulary, StRAnGER repartitions and reorders the initial distribution of terms to define a new distribution of elements. Each element pools terms holding the same enrichment score. The new distribution thus derived, is reordered in a decreasing order to the right, according to the observation score of the elements, while elements with the same score, are sorted again in a decreasing order of their enrichment scores. By applying bootstrapping techniques, a corrected measure of the statistical significance of these elements is derived, which enables the selection of terms mapped to these elements, unambiguously associated with respective significant gene sets. The selected terms are immunized against the bias infiltrating statistical enrichment analyses, producing technically very high statistical scores, due to the finite nature of the data population. Besides their high statistical score, another selection criterion for the terms is the number of their members, something that incurs a biological prioritization in line with a Systems Biology context. The output derived, represents a detailed ranked list of significant terms, which constitute a starting point for further functional analysis.

  11. Exploiting statistical methodologies and controlled vocabularies for prioritized functional analysis of genomic experiments: The StRAnGER web application

    Directory of Open Access Journals (Sweden)

    Aristotle A Chatziioannou

    2011-01-01

    Full Text Available StRAnGER is a web application for the automated statistical analysis of annotated gene profiling experiments, exploiting controlled biological vocabularies, like the Gene Ontology or the KEGG pathways terms. Starting from annotated lists of differentially expressed genes and gene enrichment scores, regarding the terms of each vocabulary, StRAnGER repartitions and reorders the initial distribution of terms to define a new distribution of elements. Each element pools terms holding the same enrichment score. The new distribution thus derived, is reordered in a decreasing order to the right, according to the observation score of the elements, while elements with the same score, are sorted again in a decreasing order of their enrichment scores. By applying bootstrapping techniques, a corrected measure of the statistical significance of these elements is derived, which enables the selection of terms mapped to these elements, unambiguously associated with respective significant gene sets. The selected terms are immunized against the bias infiltrating statistical enrichment analyses, producing technically very high statistical scores, due to the finite nature of the data population. Besides their high statistical score, another selection criterion for the terms is the number of their members, something that incurs a biological prioritization in line with a Systems Biology context. The output derived, represents a detailed ranked list of significant terms, which constitute a starting point for further functional analysis.

  12. How is RAN Related to Reading Fluency? A Comprehensive Examination of the Prominent Theoretical Accounts

    Directory of Open Access Journals (Sweden)

    TIMOTHY C PAPADOPOULOS

    2016-08-01

    Full Text Available We examined the prominent theoretical explanations of the RAN-reading relationship in a relatively transparent language (Greek in a sample of children (n= 286 followed from Grade 1 to Grade 2. Specifically, we tested the fit of eight different models, as defined by the type of reading performance predicted (oral vs. silent word reading fluency, the type of RAN tasks (non-alphanumeric vs. alphanumeric, and the RAN effects (direct vs. indirect. Working memory, attention, processing speed, and motor skills were used as common cause variables predicting both RAN and reading fluency and phonological awareness and orthographic processing were used as mediators of RAN’s effects on reading fluency. The findings of both concurrent and longitudinal analyses indicated that RAN is a unique predictor of oral reading fluency, but not silent reading fluency. Using alphanumeric or non-alphanumeric RAN did not particularly affect the RAN-reading relationship. Both phonological awareness and orthographic processing partly mediated RAN’s effects on reading fluency. Theoretical implications of these findings are discussed.

  13. Violencia doméstica en parejas homosexuales

    OpenAIRE

    Quirós Chacón, María del Camino

    2011-01-01

    La violencia doméstica dentro de las parejas homosexuales es un fenómeno apenas estudiado ya que los esfuerzos se han centrado en la violencia machista. Además, la homofobia supone una barrera importante que mantiene el maltrato en parejas del mismo sexo totalmente encubierto.

  14. Domænemodellering som grundlag for terminologier og ontologier

    DEFF Research Database (Denmark)

    Toft, Birthe

    2011-01-01

    Indlægget omhandler hvordan et sæt grundlæggende ontologiske og epistemiske kategorier, udviklet af I. Dahlberg til brug for et universelt klassifikationssystem, ICC, kan bruges som udgangspunkt for en checkliste bestående generelle spørgsmål til et givet domæne som grundlag for indledende afgræn...

  15. "Baltiiski dom" kontsa tõsjatsheletija / Eteri Kekelidze

    Index Scriptorium Estoniae

    Kekelidze, Eteri, 1944-

    1999-01-01

    Teatrifestival IX Baltiiski dom.Grand prix' võitis Moskva Taganka Teater Juri Ljubimovi lavastusega "Marat/Sade" Peter Weissi näidendi järgi, meesnäitleja preemia - Juri Itskov, lavastajapreemia - Eimuntas Nekroshius ( W. Shakespeare'i "Macbeth")

  16. "Baltiiski Dom" bez Latvii i Estonii / Boris Tuch

    Index Scriptorium Estoniae

    Tuch, Boris, 1946-

    1999-01-01

    Teatrifestival IX Baltiiski Dom.Grand prix' võitis Moskva Taganka Teater Juri Ljubimovi lavastusega "Marat/Sade" Peter Weissi näidendi järgi, meesnäitleja preemia - Juri Itskov, lavastajapreemia - Eimuntas Nekroshius ( W. Shakespeare'i "Macbeth")

  17. General and Specific Contributions of RAN to Reading and Arithmetic Fluency in First Graders: A Longitudinal Latent Variable Approach

    Directory of Open Access Journals (Sweden)

    Caroline Hornung

    2017-10-01

    Full Text Available In the present study, we opted for a longitudinal design and examined rapid automatized naming (RAN performance from two perspectives. In a first step, we examined the structure of RAN performance from a general cognitive perspective. We investigated whether rapid naming measures (e.g., digit RAN and color RAN reflect a mainly domain-general factor or domain-specific factors. In a second step, we examined how the best fitting RAN model was related to reading and arithmetic outcomes, assessed several months later. Finally in a third step we took a clinical perspective and investigated specific contributions of RAN measures to reading and arithmetic outcomes. While RAN has emerged as a promising predictor of reading, the relationship between RAN and arithmetic has been less examined in the past. Hundred and twenty-two first graders completed seven RAN tasks, each comprising visually familiar stimuli such as digits, vowels, consonants, dice, finger-numeral configurations, objects, and colors. Four months later the same children completed a range of reading and arithmetic tasks. From a general descriptive perspective, structural equation modeling supports a one-dimensional RAN factor in 6- to -7-year-old children. However, from a clinical perspective, our findings emphasize the specific contributions of RANs. Interestingly, alphanumeric RANs (i.e., vowel RAN were most promising when predicting reading skills and number-specific RANs (i.e., finger-numeral configuration RAN were most promising when predicting arithmetic fluency. The implications for clinical and educational practices will be discussed.

  18. Effect of Engine Installation on Jet Noise using a Hybrid LES/RANS Approach Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Installation effects arising from propulsion airframe interaction are known to produce substantial variations in the in-situ jet noise. A hybrid LES/RANS...

  19. Mesh Generation and Adaption for High Reynolds Number RANS Computations Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This proposal offers to provide NASA with an automatic mesh generator for the simulation of aerodynamic flows using Reynolds-Averages Navier-Stokes (RANS) models....

  20. A dynamic hybrid RANS/LES modeling methodology for turbulent/transitional flow field prediction

    Science.gov (United States)

    Alam, Mohammad Faridul

    A dynamic hybrid Reynolds-averaged Navier-Stokes (RANS)-Large Eddy Simulation (LES) modeling framework has been investigated and further developed to improve the Computational Fluid Dynamics (CFD) prediction of turbulent flow features along with laminar-to-turbulent transitional phenomena. In recent years, the use of hybrid RANS/LES (HRL) models has become more common in CFD simulations, since HRL models offer more accuracy than RANS in regions of flow separation at a reduced cost relative to LES in attached boundary layers. The first part of this research includes evaluation and validation of a dynamic HRL (DHRL) model that aims to address issues regarding the RANS-to-LES zonal transition and explicit grid dependence, both of which are inherent to most current HRL models. Simulations of two test cases---flow over a backward facing step and flow over a wing with leading-edge ice accretion---were performed to assess the potential of the DHRL model for predicting turbulent features involved in mainly unsteady separated flow. The DHRL simulation results are compared with experimental data, along with the computational results for other HRL and RANS models. In summary, these comparisons demonstrate that the DHRL framework does address many of the weaknesses inherent in most current HRL models. Although HRL models are widely used in turbulent flow simulations, they have limitations for transitional flow predictions. Most HRL models include a fully turbulent RANS component for attached boundary layer regions. The small number of HRL models that do include transition-sensitive RANS models have issues related to the RANS model itself and to the zonal transition between RANS and LES. In order to address those issues, a new transition-sensitive HRL modeling methodology has been developed that includes the DHRL methodology and a physics-based transition-sensitive RANS model. The feasibility of the transition-sensitive dynamic HRL (TDHRL) model has been investigated by

  1. Tuning a RANS k-e model for jet-in-crossflow simulations.

    Energy Technology Data Exchange (ETDEWEB)

    Lefantzi, Sophia; Ray, Jaideep; Arunajatesan, Srinivasan; DeChant, Lawrence Justin

    2013-09-01

    We develop a novel calibration approach to address the problem of predictive ke RANS simulations of jet-incrossflow. Our approach is based on the hypothesis that predictive ke parameters can be obtained by estimating them from a strongly vortical flow, specifically, flow over a square cylinder. In this study, we estimate three ke parameters, C%CE%BC, Ce2 and Ce1 by fitting 2D RANS simulations to experimental data. We use polynomial surrogates of 2D RANS for this purpose. We conduct an ensemble of 2D RANS runs using samples of (C%CE%BC;Ce2;Ce1) and regress Reynolds stresses to the samples using a simple polynomial. We then use this surrogate of the 2D RANS model to infer a joint distribution for the ke parameters by solving a Bayesian inverse problem, conditioned on the experimental data. The calibrated (C%CE%BC;Ce2;Ce1) distribution is used to seed an ensemble of 3D jet-in-crossflow simulations. We compare the ensemble's predictions of the flowfield, at two planes, to PIV measurements and estimate the predictive skill of the calibrated 3D RANS model. We also compare it against 3D RANS predictions using the nominal (uncalibrated) values of (C%CE%BC;Ce2;Ce1), and find that calibration delivers a significant improvement to the predictive skill of the 3D RANS model. We repeat the calibration using surrogate models based on kriging and find that the calibration, based on these more accurate models, is not much better that those obtained with simple polynomial surrogates. We discuss the reasons for this rather surprising outcome.

  2. An Enhanced OFDM Resource Allocation Algorithm in C-RAN Based 5G Public Safety Network

    Directory of Open Access Journals (Sweden)

    Lei Feng

    2016-01-01

    Full Text Available Public Safety Network (PSN is the network for critical communication when disaster occurs. As a key technology in 5G, Cloud-Radio Access Network (C-RAN can play an important role in PSN instead of LTE-based RAN. This paper firstly introduces C-RAN based PSN architecture and models the OFDM resource allocation problem in C-RAN based PSN as an integer quadratic programming, which allows the trade-off between expected bitrates and allocating fairness of PSN Service User (PSU. However, C-RAN based PSN needs to improve the efficiency of allocating algorithm because of a mass of PSU-RRH associations when disaster occurs. To deal with it, the resources allocating problem with integer variables is relaxed into one with continuous variables in the first step and an algorithm based on Generalized Bender’s Decomposition (GBD is proposed to solve it. Then we use Feasible Pump (FP method to get a feasible integer solution on the original OFDM resources allocation problem. The final experiments show the total throughput achieved by C-RAN based PSN is at most higher by 19.17% than the LTE-based one. And the average computational time of the proposed GBD and FP algorithm is at most lower than Barrier by 51.5% and GBD with no relaxation by 30.1%, respectively.

  3. Unraveling signatures of biogeochemical processes and the depositional setting in the molecular composition of pore water DOM across different marine environments

    Science.gov (United States)

    Schmidt, Frauke; Koch, Boris P.; Goldhammer, Tobias; Elvert, Marcus; Witt, Matthias; Lin, Yu-Shih; Wendt, Jenny; Zabel, Matthias; Heuer, Verena B.; Hinrichs, Kai-Uwe

    2017-06-01

    Dissolved organic matter (DOM) in marine sediment pore waters derives largely from decomposition of particulate organic matter and its composition is influenced by various biogeochemical and oceanographic processes in yet undetermined ways. Here, we determine the molecular inventory of pore water DOM in marine sediments of contrasting depositional regimes with ultrahigh-resolution mass spectrometry and complementary bulk chemical analyses in order to elucidate the factors that shape DOM composition. Our sample sets from the Mediterranean, Marmara and Black Seas covered different sediment depths, ages and a range of marine environments with different (i) organic matter sources, (ii) balances of organic matter production and preservation, and (iii) geochemical conditions in sediment and water column including anoxic, sulfidic and hypersaline conditions. Pore water DOM had a higher molecular formula richness than overlying water with up to 11,295 vs. 2114 different molecular formulas in the mass range of 299-600 Da and covered a broader range of element ratios (H/C = 0.35-2.19, O/C = 0.03-1.19 vs. H/C = 0.56-2.13, O/C = 0.15-1.14). Formula richness was independent of concentrations of DOC and TOC. Near-surface pore water DOM was more similar to water column DOM than to deep pore water DOM from the same core with respect to formula richness and the molecular composition, suggesting exchange at the sediment-water interface. The DOM composition in the deeper sediments was controlled by organic matter source, selective decomposition of specific DOM fractions and early diagenetic molecule transformations. Compounds in pelagic sediment pore waters were predominantly highly unsaturated and N-bearing formulas, whereas oxygen-rich CHO-formulas and aromatic compounds were more abundant in pore water DOM from terrigenous sediments. The increase of S-bearing molecular formulas in the water column and pore waters of the Black Sea and the Mediterranean Discovery Basin was

  4. Integrating empirically dissolved organic matter quality for WHAM VI using the DOM optical properties: a case study of Cu-Al-DOM interactions.

    Science.gov (United States)

    Chappaz, Anthony; Curtis, P Jeff

    2013-02-19

    Metal speciation is important for understanding the toxicity of metals in aquatic systems, and can be predicted for mixtures of metals in presence of dissolved organic matter (DOM) with thermodynamic models such as WHAM VI. The influence of the DOM source (quality) has been demonstrated, but is presently neglected in predicting Cu activity (WHAM VI). Here we determined the effect of aluminum (Al) competition on copper (Cu) complexation for four different DOMs, from a high-colored DOM (more humic) to a low-colored DOM (less humic). In presence of Al, free Cu activities (defined as free ion activity) increased, consistent with competition between Cu and Al for the same binding sites on all DOM. The apparent competition decreased with increasing DOM color. Equilibrium modeling of Cu speciation with WHAM VI explained 49% of the variance in measured Cu activity. When modified to integrate DOM quality using a new empirical coefficient F related to DOM optical properties, Cu activities predicted from WHAM VI were significantly improved to about 80% of the observed variance explained. The effects of Al on Cu activity were well predicted by WHAM VI. Subsequently, we compared the relative effects of DOM concentration, DOM quality, and Al competition with other determinants of Cu activity represented in legislation and scientific literature (pH and hardness), and qualitatively ranked them by their influence on Cu activity for normal ranges encountered in fresh waters using WHAM VI. Our experimental results indicate that DOM quality is an important variable that should be included in predictive models of ion speciation (WHAM VI) and eco-toxicological models such as the biotic ligand model (BLM).

  5. Relative control of dissolved organic matter (DOM) composition and concentration for carbon-mineral complexation

    Science.gov (United States)

    Pan, W.; Inamdar, S. P.; Sparks, D. L.; Aufdenkampe, A. K.; Yoo, K.

    2012-12-01

    Growing concern about climate change has evoked considerable interest in the soil carbon (C) pool, the second largest C-sink on the earth. C-mineral complexation formed by ligand exchange between DOM and soil is considered as the dominant mechanism for DOM sorption and stabilization in soil. Despite intensive sorption studies, our understanding of how DOM composition influences sorption is still fairly limited. The objectives of the proposed study are: (a) to investigate the relative control of DOM composition and concentration on C-mineral complexation and (b) to determine the DOM composition metrics that are associated with irreversible binding between carbon and mineral surfaces. To address these objectives, we investigated the sorption of DOM isolated and extracted from 12 different watershed sources to goethite (a-FeOOH) with batch sorption and desorption experiments. Fluorescence-EEM and UV-absorbance methods were used to characterize DOM composition through a variety of metrics. DOM composition varied considerably for the 12 DOM solutions. With all DOM solutions adjusted to a DOC concentration of 30mgC/L, humification index (HIX) value ranged from 0.18 to 0.8 and the specific UV absorbance (SUVA) ranged from 1.12 to 3.70. The increase of 2 pH units after sorption indicated ligand exchange was likely the dominant process during sorption. The aromatic and humic-like DOM substances were preferentially sorbed. Preliminary results suggest that carbon mineral complexation (OC/SSA) was influenced by both, the concentration as well as the composition of the DOM. The explanatory power of the regression equations predicting DOM sorption to goethite was increased by the including of DOM composition matrix. The sorption isotherm revealed that DOM composition has a significant influence on the shape of the isotherms.

  6. Adsorption and desorption of agricultural waste-derived DOMs in soil

    Science.gov (United States)

    Li, H. L.; Yang, G. H.; Zhu, G. Y.; Sun, Z. Q.; Yu, X. Y.

    2017-04-01

    The sorption and desorption of two forms of dissolved organic matter (DOM) extracted from agricultural wastes were studied by batch experiments. The adsorption of the two DOMs on the soil were well fitted to the Linear and Freundlich isotherms. DOM extracted from cow manure (MDOM) shows higher affinity to the soil than that extracted from wheat straw (SDOM). Significant desorption hysteresis was observed for both DOMs. Due to the desorption of some aromatic substances with larger molecular weight from the soil, the average molecular weight and aromaticity of the DOMs increased at sorption equilibrium compared with those before sorption.

  7. Determinants of Small Ubiquitin-like Modifier 1 (SUMO1) Protein Specificity, E3 Ligase, and SUMO-RanGAP1 Binding Activities of Nucleoporin RanBP2

    Energy Technology Data Exchange (ETDEWEB)

    Gareau, Jaclyn R.; Reverter, David; Lima, Christopher D. (SKI)

    2012-02-16

    The RanBP2 nucleoporin contains an internal repeat domain (IR1-M-IR2) that catalyzes E3 ligase activity and forms a stable complex with SUMO-modified RanGAP1 and UBC9 at the nuclear pore complex. RanBP2 exhibits specificity for SUMO1 as RanGAP1-SUMO1/UBC9 forms a more stable complex with RanBP2 compared with RanGAP1-SUMO2 that results in greater protection of RanGAP-SUMO1 from proteases. The IR1-M-IR2 SUMO E3 ligase activity also shows a similar preference for SUMO1. We utilized deletions and domain swap constructs in protease protection assays and automodification assays to define RanBP2 domains responsible for RanGAP1-SUMO1 protection and SUMO1-specific E3 ligase activity. Our data suggest that elements in both IR1 and IR2 exhibit specificity for SUMO1. IR1 protects RanGAP1-SUMO1/UBC9 and functions as the primary E3 ligase of RanBP2, whereas IR2 retains the ability to interact with SUMO1 to promote SUMO1-specific E3 ligase activity. To determine the structural basis for SUMO1 specificity, a hybrid IR1 construct and IR1 were used to determine three new structures for complexes containing UBC9 with RanGAP1-SUMO1/2. These structures show more extensive contacts among SUMO, UBC9, and RanBP2 in complexes containing SUMO1 compared with SUMO2 and suggest that differences in SUMO specificity may be achieved through these subtle conformational differences.

  8. Dom til fælles forældremyndighed

    DEFF Research Database (Denmark)

    Ottosen, Mai Heide; Mathilde Hansen Stage, Sofie

    de forskellige retskredse: Nogle retskredse er fx mere tilbøjelige til at idømme fælles forældremyndighed end andre. Undersøgelsen fokuserer også på, hvad der sker, når forældrene har forladt retssalen. Generelt samarbejder forældre med en dom til fælles forældremyndighed mere om barnet end dem med...... en dom om eneforældremyndighed. Alligevel kan kun halvdelen af forældrene med fælles forældremyndighed blive enige om væsentlige beslutninger vedrørende barnets forhold. Undersøgelsen bygger på et feltarbejde ved tre danske byretter, en gennemgang af alle byretssager om forældreansvar fra 2009 og en...

  9. Producción doméstica

    OpenAIRE

    Durán Heras, María Angeles

    1994-01-01

    Es un trabajo pionero que aporta una visión compleja de las economías contemporáneas que integran sistemas de producción capitalista para el mercado, sistemas de producción doméstica, sistemas de gestión por el Estado y sistemas de producción no capitalistas basados en la donación o voluntariado.

  10. Estado actual y perspectivas de la domótica

    Directory of Open Access Journals (Sweden)

    Recuero, A.

    1999-02-01

    Full Text Available An Intelligent House is the one that allows "a better quality of living through technology, a reduction of domestic tasks, an increase of the well-being and safety of dwellers, and a rationalization of the different consumers power; it includes automatized groups of equipments, usually associated by functions, which have the capacity of interactively communicate between them through an "integrated multimedia domestic bus". For this purpose, the Intelligent House foresees the execution of certain functions, depending on the information captured by measuring systems and sent through the communication network according to specific standards. This paper presents an overview of the present situation regarding these aspects, and their foreseen evolution.

    Una vivienda domótica es aquélla que, a través de la tecnología, permite "una mayor calidad de vida, una reducción del trabajo doméstico, un aumento del bienestar y la seguridad de sus habitantes, y una racionalización de los distintos consumos; en ella existen agrupaciones automatizadas de equipos, normalmente asociadas por funciones, que tienen la capacidad de comunicarse interactivamente entre ellas a través de un "bus doméstico multimedia que las integra ". Para ello, la Domótica prevé la ejecución de ciertas funciones, dependiendo de la información captada por sistemas de medida y trasmitidas a través de redes de comunicación de acuerdo con ciertos estándares. En este trabajo se revisa cuál es la situación actual de estos aspectos y cuál es su evolución previsible.

  11. Quantifying Model Form Uncertainty in RANS Simulation of Wing-Body Junction Flow

    CERN Document Server

    Wu, Jin-Long; Xiao, Heng

    2016-01-01

    Wing-body junction flows occur when a boundary layer encounters an airfoil mounted on the surface. The corner flow near the trailing edge is challenging for the linear eddy viscosity Reynolds Averaged Navier-Stokes (RANS) models, due to the interaction of two perpendicular boundary layers which leads to highly anisotropic Reynolds stress at the near wall region. Recently, Xiao et al. proposed a physics-informed Bayesian framework to quantify and reduce the model-form uncertainties in RANS simulations by utilizing sparse observation data. In this work, we extend this framework to incorporate the use of wall function in RANS simulations, and apply the extended framework to the RANS simulation of wing-body junction flow. Standard RANS simulations are performed on a 3:2 elliptic nose and NACA0020 tail cylinder joined at their maximum thickness location. Current results show that both the posterior mean velocity and the Reynolds stress anisotropy show better agreement with the experimental data at the corner regio...

  12. Rapid automatized naming (RAN) in children with ADHD: An ex-Gaussian analysis.

    Science.gov (United States)

    Ryan, Matthew; Jacobson, Lisa A; Hague, Cole; Bellows, Alison; Denckla, Martha B; Mahone, E Mark

    2017-07-01

    Children with ADHD demonstrate increased frequent "lapses" in performance on tasks in which the stimulus presentation rate is externally controlled, leading to increased variability in response times. It is less clear whether these lapses are also evident during performance on self-paced tasks, e.g., rapid automatized naming (RAN), or whether RAN inter-item pause time variability uniquely predicts reading performance. A total of 80 children aged 9 to 14 years-45 children with attention-deficit/hyperactivity disorder (ADHD) and 35 typically developing (TD) children-completed RAN and reading fluency measures. RAN responses were digitally recorded for analyses. Inter-stimulus pause time distributions (excluding between-row pauses) were analyzed using traditional (mean, standard deviation [SD], coefficient of variation [CV]) and ex-Gaussian (mu, sigma, tau) methods. Children with ADHD were found to be significantly slower than TD children (p reading fluency. RAN response time distributions were also significantly more variable (SD, tau) in children with ADHD. Hierarchical regression revealed that the exponential component (tau) of the letter-naming response time distribution uniquely predicted reading fluency in children with ADHD (p reading, ADHD symptom severity and age. The findings suggest that children with ADHD (without word-level reading difficulties) manifest slowed performance on tasks of reading fluency; however, this "slowing" may be due in part to lapses from ongoing performance that can be assessed directly using ex-Gaussian methods that capture excessively long response times.

  13. Does ability to establish sound-symbol pairings mediate the RAN reading relationship?

    DEFF Research Database (Denmark)

    Poulsen, Mads; Juul, Holger; Elbro, Carsten

    for animals in a paired associate learning task. These animals were then used in a rapid naming task. Results Preliminary results show that reading correlated with the amount of training required for learning the animal names (r=-.19, p=.06). RAN speed with the same animals did not correlate with reading......Performance on tests to rapidly name letters and digits has been shown to correlate with reading. One possible reason is that these tests probe the ability to learn and automatise symbol-sound associations. However, most studies have not controlled for the amount of experience with the RAN......-items, so it is unclear whether it is the experience or the ability to take advantage of the experience that is responsible for the correlation between RAN and reading. Paired associate learning tasks have been shown to differentiate dyslexics from controls, and to correlate with reading in unselected...

  14. Development of a Hybrid RANS/LES Method for Compressible Mixing Layer Simulations

    Science.gov (United States)

    Georgiadis, Nicholas J.; Alexander, J. Iwan D.; Reshotko, Eli

    2001-01-01

    A hybrid method has been developed for simulations of compressible turbulent mixing layers. Such mixing layers dominate the flows in exhaust systems of modem day aircraft and also those of hypersonic vehicles currently under development. The hybrid method uses a Reynolds-averaged Navier-Stokes (RANS) procedure to calculate wall bounded regions entering a mixing section, and a Large Eddy Simulation (LES) procedure to calculate the mixing dominated regions. A numerical technique was developed to enable the use of the hybrid RANS/LES method on stretched, non-Cartesian grids. The hybrid RANS/LES method is applied to a benchmark compressible mixing layer experiment. Preliminary two-dimensional calculations are used to investigate the effects of axial grid density and boundary conditions. Actual LES calculations, performed in three spatial directions, indicated an initial vortex shedding followed by rapid transition to turbulence, which is in agreement with experimental observations.

  15. Temporal Changes in Photochemically Labile DOM and Implications for Carbon Budgets in Peatland Aquatic Systems

    Science.gov (United States)

    Pickard, A.

    2015-12-01

    Aquatic systems in peatland catchments are subject to high loading of dissolved organic matter (DOM) from surrounding terrestrial environments. However the significance of photochemical transformation of DOM in peatland carbon budgets remains poorly constrained. In this study UV irradiation experiments were conducted on water samples collected over one year from two contrasting systems in Scotland: a stream draining a peatland with high levels of DOM and a reservoir draining a peat catchment with low levels of DOM. Further samples were collected from the high DOM system during two storm events. After experimental exposure, optical and chemical analyses were employed to determine photochemical lability of the DOM pool. At both sites irradiation-induced decreases in dissolved organic carbon (DOC) as a percentage of the total carbon pool were greatest in winter, suggesting that DOM was depleted in photo-reactive molecules in summer. Seasonal variability in DOC was high at the stream site and was positively correlated with CO₂ and CO photoproduction (r2 = 0.81 and 0.83, respectively; plabile DOM in headwater streams. Conservative estimates using data from this study suggest that up to 7% of the DOM pool of peatland streams can be lost (primarily as CO₂ and CO) upon exposure to 8 hours of environmentally representative UV irradiation. Further investigation in field campaigns under natural UV exposure are underway to assess the importance of photodegradation of DOM as a loss pathway of carbon based gases from aquatic systems.

  16. [DOM membrane fouling and effects on rejection behaviors of NF membranes].

    Science.gov (United States)

    Feng, Gui-Zhen; Dong, Bing-Zhi

    2013-11-01

    This work investigated membrane fouling caused by two kinds of dissolved organic matters (DOMs), i. e., Qingcaosha (QCS) DOM and Taihu lake (TH) DOM, and the effects on the rejection behaviors of two different nanofiltration (NF) membranes, i. e., HL and ESNA1-K, using carbamazepine (CBZ) as a molecular indicator. The results showed that severe membrane fouling occurred in the presence of DOM. And the CBZ removal rate was associated with the properties and characteristics of the organic matters and the membranes. It was found that the hydrophobicity of adhered DOM cake layer was responsible for the flux decline and the influence of CBZ removal. QCS DOM increased the retention of CBZ, while TH DOM decreased the rejection rate of CBZ by both membranes tested. DOMs at medium relative molecular weight (M(r) 1 500-10 000) could adhere closely to NF membranes to form cake layer, thus changed the hydrophobicity of the membranes. DOMs at low molecular weight could enter the membrane pores reducing the M(r), which influenced the CBZ removal and resulted in membrane fouling. The experiment also showed that DOM of TH contained more hydrophobic organic matters than that of QCS, the adhesion free energy and cohesion free energy of which was more negative, and the resulting membrane fouling and membrane flux decline were more severe.

  17. High-field FT-ICR mass spectrometry and NMR spectroscopy to characterize DOM removal through a nanofiltration pilot plant.

    Science.gov (United States)

    Cortés-Francisco, Nuria; Harir, Mourad; Lucio, Marianna; Ribera, Gemma; Martínez-Lladó, Xavier; Rovira, Miquel; Schmitt-Kopplin, Philipe; Hertkorn, Norbert; Caixach, Josep

    2014-12-15

    Ultrahigh resolution Fourier transform ion cyclotron mass spectrometry and nuclear magnetic resonance spectroscopy were combined to evaluate the molecular changes of dissolved organic matter (DOM) through an ultrafiltration-nanofiltration (UF-NF) pilot plant, using two dissimilar NF membranes tested in parallel. The sampling was performed on seven key locations within the pilot plant: pretreated water, UF effluent, UF effluent after addition of reagents, permeate NF 1, permeate NF 2, brine NF 1 and brine NF 2, during two sampling campaigns. The study showed that there is no significant change in the nature of DOM at molecular level, when the water was treated with UF and/or with the addition of sodium metabisulfite and antiscaling agents. However, enormous decrease of DOM concentration was observed when the water was treated on the NF membranes. The NF process preferentially removed compounds with higher oxygen and nitrogen content (more hydrophilic compounds), whereas molecules with longer pure aliphatic chains and less content of oxygen were the ones capable of passing through the membranes. Moreover, slight molecular selectivity between the two NF membranes was also observed. Copyright © 2014 Elsevier Ltd. All rights reserved.

  18. A new 3DOM Ce-Fe-Ti material for simultaneously catalytic removal of PM and NOx from diesel engines.

    Science.gov (United States)

    Cheng, Ying; Liu, Jian; Zhao, Zhen; Song, Weiyu; Wei, Yuechang

    2018-01-15

    A new 3DOM material was designed and synthesized for the simultaneous removal of PM (soot particulates) and NOx from diesel engine exhausts. The catalytic purification taking place over the material with double efficacy is cost-efficient. The contact between solid PM and catalyst active site has been process intensified by 3DOM unique structure. 3DOM Ce 0.7 Fe 0.2 Ti 0.1 O 2 catalyst possess a high SCR activity and an excellent selectivity to N 2 , giving a maximum concentration of CO 2 at 385°C for PM combustion and 100% NO conversion in the temperature range of 281-425°C. The dual redox cycles (Fe 3+ +Ce 3+ ↔Fe 2+ +Ce 4+ ,Fe 3+ +Ti 3+ ↔Fe 2+ +Ti 4+ ) and the excellent reducibility and sufficient acid sites of catalysts play key roles for the highly catalytic performance. Copyright © 2017 Elsevier B.V. All rights reserved.

  19. Elucidating the role of phenolic compounds in the effectiveness of DOM adsorption on novel tailored activated carbon.

    Science.gov (United States)

    Yan, Liang; Fitzgerald, Martha; Khov, Cindy; Schafermeyer, Amy; Kupferle, Margaret J; Sorial, George A

    2013-11-15

    Two novel tailored activated carbons (BC-41-OG and BC-41-MnN) with favorable physicochemical characteristics were successfully prepared for adsorption of dissolved natural organic matter (DOM) by applying systematically chemical and thermal treatment. This research was conducted to investigate the impact of the presence of phenolics on the adsorption capacity of DOM. Isotherm tests were performed for both humic acid (HA) and phenolics on both novel tailored activated carbons and commercial activated carbon F400. The presence of phenolics display a significant effect on hindering the adsorption of HA, however; the physicochemical characteristics of novel activated carbons (surface metal oxides and mesoporosity) can play an important role in alleviating this effect. In contrast, F400, with a relatively lower mesoporosity and surface basicity as compared to the developed adsorbents, was severely impacted by the oligomerization of phenolic compounds. The adsorption capacity of DOM in presence of phenolics was further studied in a continuous flow microcolumn system. The column results showed that both BC-41-OG and BC-41-MnN have not only higher HA adsorption capacity but also better selective adsorption ability than F400. Copyright © 2013 Elsevier B.V. All rights reserved.

  20. Model-Invariant Hybrid LES-RANS Computation of Separated Flow Past Periodic Hills

    Science.gov (United States)

    Woodruff, Stephen

    2014-01-01

    The requirement that physical quantities not vary with a hybrid LESRANS model's blending parameter imposes conditions on the computation that lead to better results across LES-RANS transitions. This promises to allow placement of those transitions so that LES is performed only where required by the physics, improving computational efficiency. The approach is applied to separated flow past periodic hills, where good predictions of separation-bubble size are seen due to the gradual, controlled, LES-RANS transition and the resulting enhanced near-wall eddy viscosity.

  1. A Cognitive Metaphorical Analysis of Selected Verses in the Glorius Qu’ran

    Directory of Open Access Journals (Sweden)

    Ahmad Abdel Tawwab Sharaf Eldin

    2015-03-01

    Full Text Available Metaphor has been generally contemplated and broke down inside the schema of verbal and written discourse, scholarly works and artistic studies. It has been identified with metaphorical language and has been viewed as quite recently a sort of aesthetic frivolity (Murray & Moon, 2006. In addition, conventional instructing of metaphors presents language as an abnormal or different method for using it (Goatly, 1997. Likewise, as Goatly has put it, scholars have needed figures of speech strictly limited to writing, talk and craftsmanship. Moreover, metaphor is viewed as something that fits in with abstract structures which is more concerned with novel or intriguing uses of words. Lakoff & Johnson (1980 presented an alternate idea and perspective of metaphor which is known as reasonable metaphorical dissection. The theory underlying this new approach is that the reasonable metaphors enter our understanding of our general surroundings and they shape our demeanor. Appropriately, as pointed out by Lakoff & Johnson (1980, metaphor is available in ordinary discourse, in every language, and is to a certain degree, has gotten to be culturally specific. Besides both contend that metaphors affect our way of viewing the meanings and are discovered widely in a significant number of our languages, contemplations and activities.

  2. Plan de negocios: soluciones domésticas de calidad

    OpenAIRE

    Mejía Rubio, Sergio

    2015-01-01

    Elaboración de un estudio de caso para obtener el grado de Maestría en Dirección y Estrategias Financieras. Para la mujer y el hombre en la actualidad se generan conflictos por el desarrollo de sus carreras y diversas actividades de índole social, atender los requerimientos de las actividades domésticas para ellos es una necesidad no satisfecha a plenitud, las razones son diversas,actividades laborales con jornadas extensas de trabajo que van de 35 a más de 48 horas (32.7% de la PEA), v...

  3. Practical JavaScript, DOM scripting and Ajax projects

    CERN Document Server

    Zammetti, Frank

    2007-01-01

    JavaScript is hugely poplar in modern web development. It has good support in modern web browsers and improved development practices, leading to much interest in topics such as Ajax and DOM Scripting.This ""learn by example"" book offers 10 complete JavaScript projects that will save web developers countless hours of development time. These projects can serve as samples to learn from and/or be adapted for use in other projects. The 10 projects all address common needs in modern web applications, including a utility library, a validation framework, a GUI widget framework, a dynamic event calend

  4. Ignacio Doménech, editor y autor culinario

    OpenAIRE

    Simón Palmer, María del Carmen

    2012-01-01

    Ignacio Doménech simboliza la modernidad en la cocina española desde finales del siglo XIX. De formación europea, comprende la importancia de transmitir los conocimientos profesionales y lo hará de tres formas: la realización práctica de menús, la enseñanza, para lo que crea la primera escuela de cocina, y la edición de textos. Como editor mantendrá durante cuarenta años la revista El Gorro Blanco, al tiempo que publica gran cantidad de libros ilustrados por los mejores dibujan...

  5. Modelling of sand transport under wave-generated sheet flows with a RANS diffusion model

    NARCIS (Netherlands)

    Hassan, Wael; Ribberink, Jan S.

    2010-01-01

    A 1DV-RANS diffusion model is used to study sand transport processes in oscillatory flat-bed/sheet flow conditions. The central aim is the verification of the model with laboratory data and to identify processes controlling the magnitude and direction (‘onshore’/‘offshore’) of the net time-averaged

  6. Computing the flow past Vortex Generators : Comparison between RANS Simulations and Experiments

    NARCIS (Netherlands)

    Manolesos, M.; Sorensen, NN; Troldborg, N.; Florentie, L.; Papadakis, G; Voutsinas, S.

    2016-01-01

    The flow around a wind turbine airfoil equipped with Vortex Generators (VGs) is examined. Predictions from three different Reynolds Averaged Navier Stokes (RANS) solvers with two different turbulence models and two different VG modelling approaches are compared between them and with experimental

  7. Computing the flow past Vortex Generators: Comparison between RANS Simulations and Experiments

    DEFF Research Database (Denmark)

    Manolesos, M.; Sørensen, Niels N.; Troldborg, Niels

    2016-01-01

    The flow around a wind turbine airfoil equipped with Vortex Generators (VGs) is examined. Predictions from three different Reynolds Averaged Navier Stokes (RANS) solvers with two different turbulence models and two different VG modelling approaches are compared between them and with experimental ...

  8. Inadequacy representation of flamelet-based RANS model for turbulent non-premixed flame

    Science.gov (United States)

    Lee, Myoungkyu; Oliver, Todd; Moser, Robert

    2017-11-01

    Stochastic representations for model inadequacy in RANS-based models of non-premixed jet flames are developed and explored. Flamelet-based RANS models are attractive for engineering applications relative to higher-fidelity methods because of their low computational costs. However, the various assumptions inherent in such models introduce errors that can significantly affect the accuracy of computed quantities of interest. In this work, we develop an approach to represent the model inadequacy of the flamelet-based RANS model. In particular, we pose a physics-based, stochastic PDE for the triple correlation of the mixture fraction. This additional uncertain state variable is then used to construct perturbations of the PDF for the instantaneous mixture fraction, which is used to obtain an uncertain perturbation of the flame temperature. A hydrogen-air non-premixed jet flame is used to demonstrate the representation of the inadequacy of the flamelet-based RANS model. This work was supported by DARPA-EQUiPS(Enabling Quantification of Uncertainty in Physical Systems) program.

  9. Optimal Assignment of Cells in C-RAN Deployments with Multiple BBU Pools

    DEFF Research Database (Denmark)

    Holm, Henrik; Checko, Aleksandra; Al-obaidi, Rami

    2015-01-01

    recommend to divide the area into multiple BBU Pools. In this paper we show how to optimally assign cells to different BBU Pools in such a scenario. By using Integer Linear Programming (ILP) method we derive engineering guidelines for minimizing the CAPital EXpenditure (CAPEX) of C-RAN deployment....

  10. Western Culture in Japanese Film: Kurosawa's "Throne of Blood" and "Ran."

    Science.gov (United States)

    Kane, Peter E.

    Akira Kurosawa, the most popular Asian film maker with audiences in the United States, has found in William Shakespeare's plays themes and plots that resonate within Japanese culture. While the translations of "Macbeth" into "Throne of Blood" and "King Lear" into "Ran" are quite direct and literal with only…

  11. Analysis of vegetation effect on waves using a vertical 2-D RANS model

    Science.gov (United States)

    A vertical two-dimensional (2-D) model has been applied in the simulation of wave propagation through vegetated water bodies. The model is based on an existing model SOLA-VOF which solves the Reynolds-Averaged Navier-Stokes (RANS) equations with the finite difference method on a staggered rectangula...

  12. Optimizing Cloud-RAN Deployments in Real-life Scenarios Using Microwave Radio

    DEFF Research Database (Denmark)

    Al-obaidi, Rami; Checko, Aleksandra; Holm, Henrik

    2015-01-01

    derive engineering guidelines for minimizing the CAPital EXpenditure (CAPEX) of C-RAN deployment. We show for which population density and span of BBU Pool coverage usage of Microwave Radio (MWR) links is viable. For larger scale deployment we recommend to divide the area into multiple BBU Pools....

  13. Ardo Ran Varres elustab härra Tartüffi / Tiit Tuumalu

    Index Scriptorium Estoniae

    Tuumalu, Tiit, 1971-

    2005-01-01

    2.-9. septembrini Pärnus, Haapsalus, Tallinnas, Viljandis ja Tartus toimuvast tummfilmi ühe olulisema lavastaja F. W. Murnau "Tartüff" filmikontserdist "Tartüff live", esitaja Varrese ansambel ARV Ensemble. Ardo Ran Varrese töödest

  14. RANS Modeling of Benchmark Shockwave / Boundary Layer Interaction Experiments

    Science.gov (United States)

    Georgiadis, Nick; Vyas, Manan; Yoder, Dennis

    2010-01-01

    This presentation summarizes the computations of a set of shock wave / turbulent boundary layer interaction (SWTBLI) test cases using the Wind-US code, as part of the 2010 American Institute of Aeronautics and Astronautics (AIAA) shock / boundary layer interaction workshop. The experiments involve supersonic flows in wind tunnels with a shock generator that directs an oblique shock wave toward the boundary layer along one of the walls of the wind tunnel. The Wind-US calculations utilized structured grid computations performed in Reynolds-averaged Navier-Stokes mode. Three turbulence models were investigated: the Spalart-Allmaras one-equation model, the Menter Shear Stress Transport wavenumber-angular frequency two-equation model, and an explicit algebraic stress wavenumber-angular frequency formulation. Effects of grid resolution and upwinding scheme were also considered. The results from the CFD calculations are compared to particle image velocimetry (PIV) data from the experiments. As expected, turbulence model effects dominated the accuracy of the solutions with upwinding scheme selection indicating minimal effects.!

  15. Effect of dissolved organic matter source and character on microbial Hg methylation in Hg–S–DOM solutions

    Science.gov (United States)

    Graham, Andrew M.; Aiken, George R.; Gilmour, Cynthia

    2013-01-01

    Dissolved organic matter (DOM) is a key component of fate and transport models for most metals, including mercury (Hg). Utilizing a suite of diverse DOM isolates, we demonstrated that DOM character, in addition to concentration, influences inorganic Hg (Hg(II)i) bioavailability to Hg-methylating bacteria. Using a model Hg-methylating bacterium, Desulfovibrio desulfuricansND132, we evaluated Hg-DOM-sulfide bioavailability in washed-cell assays at environmentally relevant Hg/DOM ratios (∼1–8 ng Hg/mg C) and sulfide concentrations (1–1000 μM). All tested DOM isolates significantly enhanced Hg methylation above DOM-free controls (from ∼2 to >20-fold for 20 mg C/L DOM solutions), but high molecular weight/highly aromatic DOM isolates and/or those with high sulfur content were particularly effective at enhancing Hg methylation. Because these experiments were conducted under conditions of predicted supersaturation with respect to metacinnabar (β-HgS(s)), we attribute the DOM-dependent enhancement of Hg(II)i bioavailability to steric and specific chemical (e.g., DOM thiols) inhibition of β-HgS(s) growth and aggregation by DOM. Experiments examining the role of DOM across a wide sulfide gradient revealed that DOM only enhances Hg methylation under fairly low sulfide conditions (≲30 μM), conditions that favor HgS nanoparticle/cluster formation relative to dissolved HgS species.

  16. Steady RANS methodology for calculating pressure drop in an in-line molten salt compact crossflow heat exchanger

    Energy Technology Data Exchange (ETDEWEB)

    Carasik, Lane B.; Shaver, Dillon R.; Hassan, Yassin A.; Haefner, Jonah B.

    2017-11-01

    The development of molten salt cooled reactors (MSR) and fluoride-salt cooled high temperature reactors (FHR) requires the use of advanced design tools for the primary heat exchanger design. Due to geometric and flow characteristics, compact (pitch to diameter ratios equal to or less than 1.25) heat exchangers with a crossflow flow arrangement can become desirable for these reactors. Unfortunately, the available experimental data is limited for compact tube bundles or banks in crossflow. Computational Fluid Dynamics can be used to alleviate the lack of experimental data in these tube banks. Previous computational efforts have been primarily focused on large S/D ratios (larger than 1.4) using unsteady Reynolds averaged Navier-Stokes and Large Eddy Simulation frameworks. These approaches are useful, but have large computational requirements that make comprehensive design studies impractical. A CFD study was conducted with steady RANS in an effort to provide a starting point for future design work. The study was performed for an in-line tube bank geometry with FLiBe (LiF-BeF2), a frequently selected molten salt, as the working fluid. Based on the estimated pressure drops, the pressure and velocity distributions in the domain, an appropriate meshing strategy was determined and presented. Periodic boundaries in the spanwise direction transverse flow were determined to be an appropriate boundary condition for reduced computational domains. The domain size was investigated and a minimum of 2-flow channels for a domain is recommended to ensure the behavior is accounted for. Lastly, the standard low Re κ-ε (Lien) turbulence model was determined to be the most appropriate for steady RANS of this case at the time of writing.

  17. ran Bonde - landsköpman och bondeseglare på 1500-talet / Bengt Eriksson

    Index Scriptorium Estoniae

    Eriksson, Bengt

    2012-01-01

    Üle Soome lahe kaubandusest 16. sajandil. Helsingi kihelkonnas tegutsenud kaupmehest Göran Bondest, kes käis aastas 5-6 korda kaubareisil Tallinnas. Tihedamad suhted sidusid Göran Bondet Tallinna kaupmehe Hemlich Fickega. "Läänemere valitsejast" Sören Norrbyst. Helsingi rajamisest Gustav I Vasa poolt vastukaaluks Tallinnale

  18. X3DOM AS CARRIER OF THE VIRTUAL HERITAGE

    Directory of Open Access Journals (Sweden)

    Y. Jung

    2012-09-01

    Full Text Available Virtual Museums (VM are a new model of communication that aims at creating a personalized, immersive, and interactive way to enhance our understanding of the world around us. The term "VM" is a short-cut that comprehends various types of digital creations. One of the carriers for the communication of the virtual heritage at future internet level as de-facto standard is browser front-ends presenting the content and assets of museums. A major driving technology for the documentation and presentation of heritage driven media is real-time 3D content, thus imposing new strategies for a web inclusion. 3D content must become a first class web media that can be created, modified, and shared in the same way as text, images, audio and video are handled on the web right now. A new integration model based on a DOM integration into the web browsers' architecture opens up new possibilities for declarative 3 D content on the web and paves the way for new application scenarios for the virtual heritage at future internet level. With special regards to the X3DOM project as enabling technology for declarative 3D in HTML, this paper describes application scenarios and analyses its technological requirements for an efficient presentation and manipulation of virtual heritage assets on the web.

  19. Characterization of DOM in landfill leachate polluted groundwater with electrospary LC-MS

    DEFF Research Database (Denmark)

    Persson, L.; Alsberg, T.; Odham, G.

    2001-01-01

    Dissolved organic matter in leachate polluted groundwater, downgradient a landfill, was analysed with electrospray mass spectrometry. The results indicate that the DOM change qualitatively in the gradient, becoming more uniform in functional groups and hydrofobicity. Those changes may affect...... the DOM facilitated transport of pollutants....

  20. Strong linkages between DOM optical properties and main clades of aquatic bacteria

    DEFF Research Database (Denmark)

    Amaral, Valentina; Graeber, Daniel; Calliari, Danilo

    2016-01-01

    Despite considerable research on the linkages between dissolved organic matter (DOM) and bacteria, it is not yet clear how the abundance of the main aquatic clades relates to DOM composition in natural aquatic systems. We evaluated this relation using PARAFAC modeling of excitation......–emission fluorescence spectroscopy and spectroscopic indexes to characterize DOM composition, and fluorescence in situ hybridization, to quantify the major bacterial groups in a subtropical lagoon. The DOM exhibited marked temporal variations in concentration, molecular weight, aromaticity, color, degree...... of humification, and freshness, and proportion of the three different fluorescent components identified. All major bacterial clades (Alphaproteobacteria, Betaproteobacteria, Gammaproteobacteria, and Cytophaga-Flavobacteria) were significantly linked to DOM concentration and/or composition, being those crucial...

  1. The Ran GTPase-activating protein (RanGAP1 is critically involved in smooth muscle cell differentiation, proliferation and migration following vascular injury: implications for neointima formation and restenosis.

    Directory of Open Access Journals (Sweden)

    Marc Vorpahl

    Full Text Available Differentiation and dedifferentiation, accompanied by proliferation play a pivotal role for the phenotypic development of vascular proliferative diseases (VPD, such as restenosis. Increasing evidence points to an essential role of regulated nucleoporin expression in the choice between differentiation and proliferation. However, whether components of the Ran GTPase cycle, which is of pivotal importance for both nucleocytoplasmic transport and for mitotic progression, are subject to similar regulation in VPD is currently unknown. Here, we show that differentiation of human coronary artery smooth muscle cell (CASMC to a contractile phenotype by stepwise serum depletion leads to significant reduction of RanGAP1 protein levels. The inverse event, dedifferentiation of cells, was assessed in the rat carotid artery balloon injury model, a well-accepted model for neointima formation and restenosis. As revealed by temporospatial analysis of RanGAP1 expression, neointima formation in rat carotid arteries was associated with a significant upregulation of RanGAP1 expression at 3 and 7 days after balloon injury. Of note, neointimal cells located at the luminal surface revealed persistent RanGAP1 expression, as opposed to cells in deeper layers of the neointima where RanGAP1 expression was less or not detectable at all. To gain first evidence for a direct influence of RanGAP1 levels on differentiation, we reduced RanGAP1 in human coronary artery smooth muscle cells by siRNA. Indeed, downregulation of the essential RanGAP1 protein by 50% induced a differentiated, spindle-like smooth muscle cell phenotype, accompanied by an upregulation of the differentiation marker desmin. Reduction of RanGAP1 levels also resulted in a reduction of mitogen induced cellular migration and proliferation as well as a significant upregulation of the cyclin-dependent kinase inhibitor p27KIP1, without evidence for cellular necrosis. These findings suggest that RanGAP1 plays a critical

  2. The Ran GTPase-activating protein (RanGAP1) is critically involved in smooth muscle cell differentiation, proliferation and migration following vascular injury: implications for neointima formation and restenosis.

    Science.gov (United States)

    Vorpahl, Marc; Schönhofer-Merl, Sabine; Michaelis, Cornelia; Flotho, Annette; Melchior, Frauke; Wessely, Rainer

    2014-01-01

    Differentiation and dedifferentiation, accompanied by proliferation play a pivotal role for the phenotypic development of vascular proliferative diseases (VPD), such as restenosis. Increasing evidence points to an essential role of regulated nucleoporin expression in the choice between differentiation and proliferation. However, whether components of the Ran GTPase cycle, which is of pivotal importance for both nucleocytoplasmic transport and for mitotic progression, are subject to similar regulation in VPD is currently unknown. Here, we show that differentiation of human coronary artery smooth muscle cell (CASMC) to a contractile phenotype by stepwise serum depletion leads to significant reduction of RanGAP1 protein levels. The inverse event, dedifferentiation of cells, was assessed in the rat carotid artery balloon injury model, a well-accepted model for neointima formation and restenosis. As revealed by temporospatial analysis of RanGAP1 expression, neointima formation in rat carotid arteries was associated with a significant upregulation of RanGAP1 expression at 3 and 7 days after balloon injury. Of note, neointimal cells located at the luminal surface revealed persistent RanGAP1 expression, as opposed to cells in deeper layers of the neointima where RanGAP1 expression was less or not detectable at all. To gain first evidence for a direct influence of RanGAP1 levels on differentiation, we reduced RanGAP1 in human coronary artery smooth muscle cells by siRNA. Indeed, downregulation of the essential RanGAP1 protein by 50% induced a differentiated, spindle-like smooth muscle cell phenotype, accompanied by an upregulation of the differentiation marker desmin. Reduction of RanGAP1 levels also resulted in a reduction of mitogen induced cellular migration and proliferation as well as a significant upregulation of the cyclin-dependent kinase inhibitor p27KIP1, without evidence for cellular necrosis. These findings suggest that RanGAP1 plays a critical role in smooth

  3. Evaluating C-RAN Fronthaul Functional Splits in Terms of Network Level Energy and Cost Savings

    DEFF Research Database (Denmark)

    Checko, Aleksandra; Popovska Avramova, Andrijana; Berger, Michael Stübert

    2016-01-01

    split in the baseband processing chain has been proposed to overcome these challenges. This paper evaluates, by mathematical and simulation methods, different splits with respect to network level energy and cost efficiency having in the mind the expected quality of service.The proposed mathematical......The placement of the complete baseband processing in a centralized pool results in high data rate requirement and inflexibility of the fronthaul network, which challenges the energy and cost effectiveness of the cloud radio access network (C-RAN). Recently, redesign of the C-RAN through functional...... model quantifies the multiplexing gains and the trade-offs between centralization and decentralization concerning the cost of the pool, fronthaul network capacity and resource utilization. The event-based simulation captures the influence of the traffic load dynamics and traffic type variation...

  4. Enhancing LTE with Cloud-RAN and Load-Controlled Parasitic Antenna Arrays

    DEFF Research Database (Denmark)

    Artuso, Matteo; Boviz, Dora; Checko, Aleksandra

    2016-01-01

    implementations of C-RANs tackle fundamental technical and economic challenges. In this article, we present an end-to-end solution for practically implementable C-RANs by providing innovative solutions to key issues such as the design of cost-effective hardware and power-effective signals for RRHs, efficient...... design and distribution of data and control traffic for coordinated communications, and conception of a flexible and elastic architecture supporting dynamic allocation of both the densely distributed RRHs and the centralized processing resources in the cloud to create virtual base stations. More...... specifically, we propose a novel antenna array architecture called load-controlled parasitic antenna array (LCPAA) where multiple antennas are fed by a single RF chain. Energy- and spectral-efficient modulation as well as signaling schemes that are easy to implement are also provided. Additionally, the design...

  5. On the use of (U)RANS and LES approaches for turbulent incompressible single phase flows in nuclear engineering applications

    Energy Technology Data Exchange (ETDEWEB)

    Benhamadouche, Sofiane, E-mail: sofiane.benhamadouche@edf.fr

    2017-02-15

    Highlights: • The paper deals with the use of (U)RANS and LES in nuclear engineering applications. • It gives some ideas and guidelines to run high quality computations. • Some perspectives are drawn concerning the development of (U)RANS and LES approaches in the future. - Abstract: The present paper gives some ideas and guidelines in order to run high quality (U)RANS or LES computations. The paper starts with (U)RANS approaches, advocating the use of Reynolds Stress Models for complex flows and recommending further work on modeling of turbulent heat fluxes, which remains today too basic in industry. The superiority of wall-resolved models vs. wall-modeled in RANS is recalled and the use of adaptive wall treatment is suggested. The concept of Unsteady RANS is finally questioned. Then, important issues around LES are raised. The mesh refinement criteria are recalled for wall-resolved LES and the use of wall models addressed. The production of DNS and wall-resolved LES calculations for flow understanding and RANS validation is encouraged.

  6. [Oceanography and King Dom Carlos I's collection of iconography].

    Science.gov (United States)

    Jardim, Maria Estela; Peres, Isabel Marília; Ré, Pedro Barcia; Costa, Fernanda Madalena

    2014-01-01

    After the Challenger expedition (1872-1878), other nations started to show interest in oceanographic research and organizing their own expeditions. As of 1885, Prince Albert I of Monaco conducted oceanographic campaigns with the collaboration of some of the best marine biologists and physical oceanographers of the day, inventing new techniques and instruments for the oceanographic work. Prince Albert's scientific activity certainly helped kindle the interest of his friend, Dom Carlos I, king of Portugal, in the study of the oceans and marine life. Both shared the need to use photography to document their studies. This article analyzes the role of scientific photography in oceanography, especially in the expeditions organized by the Portuguese monarch.

  7. Paredes de domínios em ferromagnetismo

    OpenAIRE

    Rudnei de Oliveira Ramos

    1989-01-01

    Determinamos a tensão superficial de um defeito do tipo parede de domínio, utilizando a aproximação semiclássica no contexto da teoria de campos à temperatura finita para o modelo ? (?2)2 com interação invariante por simetria O(N), obtendo em seguida a temperatura crítica Tc de transição de fase e cálculo dos expoentes críticos ? e ?, aplicando então os resultados obtidos para a descrição de um modelo fenomenológico descrevendo o ferromagnetismo. We determine the surface tension...

  8. Computing the flow past Vortex Generators: Comparison between RANS Simulations and Experiments

    Science.gov (United States)

    Manolesos, M.; Sørensen, N. N.; Troldborg, N.; Florentie, L.; Papadakis, G.; Voutsinas, S.

    2016-09-01

    The flow around a wind turbine airfoil equipped with Vortex Generators (VGs) is examined. Predictions from three different Reynolds Averaged Navier Stokes (RANS) solvers with two different turbulence models and two different VG modelling approaches are compared between them and with experimental data. The best results are obtained with the more expensive fully resolved VG approach. The cost efficient BAY model can also provide acceptable results, if grid related numerical diffusion is minimized and only force coefficient polars are considered.

  9. A comparison between Smoothed-Particle Hydrodynamics and RANS Volume of Fluid method in modelling slamming

    Directory of Open Access Journals (Sweden)

    Marcus Sasson

    2016-04-01

    Full Text Available The oil and gas industry requires complex subsea infrastructure in order to develop offshore oil and gas fields. Upon installation, these components may encounter high slamming loads, stemming from impact with the water surface. This paper utilises two different numerical methods, the mesh-free Smoothed Particle Hydrodynamics (SPH approach and Reynolds Averaged Navier–Stokes (RANS Volume of Fluid (VOF method to quantify these loads on a free-falling object. The investigation is also interested in conducting a parameter study and determining the effect of varying simulation parameters on the prediction of slamming event kinematics and forces. The surface impact of a freefalling wedge was introduced as a case study and has been simulated using SPH and RANS, with the results being compared to an experimental investigation. It was found from the SPH simulations that particle resolution and the size of the SPH particle kernel are very important, whilst the diffusion term does not play an important role. The latter is due to the very transient nature of slamming events, which do not allow sufficient time for diffusion in the fluid domain. For the RANS simulations, motion of the wedge was achieved using the overset grid technique, whereby varying the discretising time step was found to have a pronounced impact on the accuracy of the captured slamming event. Through analysing the numerical data, one can observe that the RANS results correlate slightly better with the experimental data as opposed to that obtained from the SPH modelling. However, considering the robustness and quick set up of the SPH simulations, both of these two numerical approaches are considered to be promising tools for modelling more complicated slamming problems, including those potentially involving more intricate structures.

  10. Propeller Analysis Using RANS/BEM Coupling Accounting for Blade Blockage

    Science.gov (United States)

    2015-07-04

    2000 and 2010 Gothenburg and 2005 Tokyo workshops on numerical ship hydrodynamics (Larrson et al., 2002, Larsson et al. 2013, Hino 2005). The KCS is...Workshop on Numerical Ship Hydrodynamics, Chalmers University of Technology. Larsson , L., Stern, F. and Visonneau, M. (eds.), (2013). Numerical ...B2Y 3Z7 ABSTRACT A popular method for analyzing a propeller operating behind a ship is to couple a Reynolds-averaged Navier- Stokes (RANS) solution

  11. RANS/CAA based Prediction of Jet Mixing Noise in Cruise Flight

    OpenAIRE

    Appel, Christina; Rossignol, Karl-Stéphane; Klabes, Alexander; Neifeld, Andrej; Herr, Michaela; Ewert, Roland

    2014-01-01

    Besides turbulent boundary layer induced excitation noise, jet noise is the second most important aeroacoustic source for aircraft cabin noise. A goal within the DLR project ECCO (Enhanced Cabin Comfort Computations) was to improve current cabin noise pre- diction approaches. Within the framework of the project ECCO RANS (Reynolds Averaged Navier Stokes) and CAA (Computational Aero Acoustics) computations for jet noise at cruise conditions have been carried out. Especially at h...

  12. Application of Les, Pans and Rans to a Case of Intake Channel Steady Flow Test Bench

    Directory of Open Access Journals (Sweden)

    Vítek Oldřich

    2015-12-01

    Full Text Available The paper deals with evaluation of intake channel flow properties (discharge coefficient, tumble and swirl ratio using both 3-D CFD simulation and measurement. Sensitivity of different calculation parameters was tested. The most important ones are mesh parameters and applied turbulence models (considered models: LES, PANS and RANS. Concerning the mesh, the critical parameter is a mesh configuration near a wall - a thickness of mesh boundary layer and an amount of these layers have significant impact on mass flow rate while tumble/swirl ratio is unaffected by that. Based on that, these mesh parameters can be considered as tuning constants for fine-tuning the CFD model. Regarding the mesh cell size, 2 different values were tested (0.6 and 0.3 mm. It was found out that neither mesh is fine enough to perform proper LES. Hence, PANS performance is close to RANS. Concerning the turbulence models, PANS seems to be the best one as it combines advantages of both LES and RANS. Generally speaking, mass flow rate prediction is relatively good while swirl/tumble one is more problematic as only qualitative agreement can be achieved.

  13. Accurate load prediction by BEM with airfoil data from 3D RANS simulations

    Science.gov (United States)

    Schneider, Marc S.; Nitzsche, Jens; Hennings, Holger

    2016-09-01

    In this paper, two methods for the extraction of airfoil coefficients from 3D CFD simulations of a wind turbine rotor are investigated, and these coefficients are used to improve the load prediction of a BEM code. The coefficients are extracted from a number of steady RANS simulations, using either averaging of velocities in annular sections, or an inverse BEM approach for determination of the induction factors in the rotor plane. It is shown that these 3D rotor polars are able to capture the rotational augmentation at the inner part of the blade as well as the load reduction by 3D effects close to the blade tip. They are used as input to a simple BEM code and the results of this BEM with 3D rotor polars are compared to the predictions of BEM with 2D airfoil coefficients plus common empirical corrections for stall delay and tip loss. While BEM with 2D airfoil coefficients produces a very different radial distribution of loads than the RANS simulation, the BEM with 3D rotor polars manages to reproduce the loads from RANS very accurately for a variety of load cases, as long as the blade pitch angle is not too different from the cases from which the polars were extracted.

  14. Data-free and data-driven spectral perturbations for RANS UQ

    Science.gov (United States)

    Edeling, Wouter; Mishra, Aashwin; Iaccarino, Gianluca

    2017-11-01

    Despite recent developments in high-fidelity turbulent flow simulations, RANS modeling is still vastly used by industry, due to its inherent low cost. Since accuracy is a concern in RANS modeling, model-form UQ is an essential tool for assessing the impacts of this uncertainty on quantities of interest. Applying the spectral decomposition to the modeled Reynolds-Stress Tensor (RST) allows for the introduction of decoupled perturbations into the baseline intensity (kinetic energy), shape (eigenvalues), and orientation (eigenvectors). This constitutes a natural methodology to evaluate the model form uncertainty associated to different aspects of RST modeling. In a predictive setting, one frequently encounters an absence of any relevant reference data. To make data-free predictions with quantified uncertainty we employ physical bounds to a-priori define maximum spectral perturbations. When propagated, these perturbations yield intervals of engineering utility. High-fidelity data opens up the possibility of inferring a distribution of uncertainty, by means of various data-driven machine-learning techniques. We will demonstrate our framework on a number of flow problems where RANS models are prone to failure. This research was partially supported by the Defense Advanced Research Projects Agency under the Enabling Quantification of Uncertainty in Physical Systems (EQUiPS) project (technical monitor: Dr Fariba Fahroo), and the DOE PSAAP-II program.

  15. Nuclear size is sensitive to NTF2 protein levels in a manner dependent on Ran binding

    Science.gov (United States)

    Vuković, Lidija D.; Jevtić, Predrag; Zhang, Zhaojie; Stohr, Bradley A.; Levy, Daniel L.

    2016-01-01

    ABSTRACT Altered nuclear size is associated with many cancers, and determining whether cancer-associated changes in nuclear size contribute to carcinogenesis necessitates an understanding of mechanisms of nuclear size regulation. Although nuclear import rates generally positively correlate with nuclear size, NTF2 levels negatively affect nuclear size, despite the role of NTF2 (also known as NUTF2) in nuclear recycling of the import factor Ran. We show that binding of Ran to NTF2 is required for NTF2 to inhibit nuclear expansion and import of large cargo molecules in Xenopus laevis egg and embryo extracts, consistent with our observation that NTF2 reduces the diameter of the nuclear pore complex (NPC) in a Ran-binding-dependent manner. Furthermore, we demonstrate that ectopic NTF2 expression in Xenopus embryos and mammalian tissue culture cells alters nuclear size. Finally, we show that increases in nuclear size during melanoma progression correlate with reduced NTF2 expression, and increasing NTF2 levels in melanoma cells is sufficient to reduce nuclear size. These results show a conserved capacity for NTF2 to impact on nuclear size, and we propose that NTF2 might be a new cancer biomarker. PMID:26823604

  16. Nercc1, a mammalian NIMA-family kinase, binds the Ran GTPase and regulates mitotic progression.

    Science.gov (United States)

    Roig, Joan; Mikhailov, Alexei; Belham, Christopher; Avruch, Joseph

    2002-07-01

    The protein kinase NIMA is an indispensable pleiotropic regulator of mitotic progression in Aspergillus. Although several mammalian NIMA-like kinases (Neks) are known, none appears to have the broad importance for mitotic regulation attributed to NIMA. Nercc1 is a new NIMA-like kinase that regulates chromosome alignment and segregation in mitosis. Its NIMA-like catalytic domain is followed by a noncatalytic tail containing seven repeats homologous to those of the Ran GEF, RCC1, a Ser/Thr/Pro-rich segment, and a coiled-coil domain. Nercc1 binds to another NIMA-like kinase, Nek6, and also binds specifically to the Ran GTPase through both its catalytic and its RCC1-like domains, preferring RanGDP in vivo. Nercc1 exists as a homooligomer and can autoactivate in vitro by autophosphorylation. Nercc1 is a cytoplasmic protein that is activated during mitosis and is avidly phosphorylated by active p34(Cdc2). Microinjection of anti-Nercc1 antibodies in prophase results in spindle abnormalities and/or chromosomal misalignment. In Ptk2 cells the outcome is prometaphase arrest or aberrant chromosome segregation and aneuploidy, whereas in CFPAC-1 cells prolonged arrest in prometaphase is the usual response. Nercc1 and its partner Nek6 represent a new signaling pathway that regulates mitotic progression.

  17. Studies of the DOM aqueous extracts from coastal marine sediments

    Science.gov (United States)

    Sakellariadou, F.

    2012-04-01

    Dissolved organic matter (DOM) represents a major exchangeable organic pool playing an outstanding role in the ocean carbon cycle. It has a complex chemical structure made up of a wide range of organic molecules. The composition of DOM depends on the sources proximity and the exposure to any sort of degradation mechanism. The coloured (or chromophoric) dissolved organic matter (CDOM), representing the optically active fraction of DOM, consists of aromatic rings able to absorb light in the visible and UV regions (Kirk, 1994) and fluorophoric molecules that emit light. The main fluorophoric moieties of CDOM are humic material with a blue fluorescence and protein material with an ultraviolet (UV) fluorescence (Mopper and Schultz, 1993). Dissolved organic matter interacts with pollutants either by enhancing their bioavailability or by influencing their transportation to the soluble phase. In addition, DOM affects the remineralisation of carbon and its preservation in marine sediments. Referring to its origin, it can be terrestrial, freshwater or marine one. Fluorescence spectroscopy is a technique widely applied for the identification and characterization of organic matter, being fast, simple, non-destructive and sensitive. In addition, the fluorescence analysis for the physico-chemical characterization of organic matter requires a small amount of aqueous sample at a low concentration, in comparison with the large sample volumes needed for conventional techniques. At the present study coastal sediment samples were collected from Messiniakos gulf in the south western Peloponnese in South Greece. Messiniakos gulf has a seabed dominated by very abrupt inclinations reaching depths of more than 1000m. All samples, according to their grain size, are classified as fine clayey silt. Dissolved organic matter was extracted under gentle extraction conditions (4 mM CaCl2 solution). The various classes of organic components present at the DOM aqueous extracts were characterised by

  18. Unsteady Three-Dimensional Simulation of a Shear Coaxial GO2/GH2 Rocket Injector with RANS and Hybrid-RAN-LES/DES Using Flamelet Models

    Science.gov (United States)

    Westra, Doug G.; West, Jeffrey S.; Richardson, Brian R.

    2015-01-01

    Historically, the analysis and design of liquid rocket engines (LREs) has relied on full-scale testing and one-dimensional empirical tools. The testing is extremely expensive and the one-dimensional tools are not designed to capture the highly complex, and multi-dimensional features that are inherent to LREs. Recent advances in computational fluid dynamics (CFD) tools have made it possible to predict liquid rocket engine performance, stability, to assess the effect of complex flow features, and to evaluate injector-driven thermal environments, to mitigate the cost of testing. Extensive efforts to verify and validate these CFD tools have been conducted, to provide confidence for using them during the design cycle. Previous validation efforts have documented comparisons of predicted heat flux thermal environments with test data for a single element gaseous oxygen (GO2) and gaseous hydrogen (GH2) injector. The most notable validation effort was a comprehensive validation effort conducted by Tucker et al. [1], in which a number of different groups modeled a GO2/GH2 single element configuration by Pal et al [2]. The tools used for this validation comparison employed a range of algorithms, from both steady and unsteady Reynolds Averaged Navier-Stokes (U/RANS) calculations, large-eddy simulations (LES), detached eddy simulations (DES), and various combinations. A more recent effort by Thakur et al. [3] focused on using a state-of-the-art CFD simulation tool, Loci/STREAM, on a two-dimensional grid. Loci/STREAM was chosen because it has a unique, very efficient flamelet parameterization of combustion reactions that are too computationally expensive to simulate with conventional finite-rate chemistry calculations. The current effort focuses on further advancement of validation efforts, again using the Loci/STREAM tool with the flamelet parameterization, but this time with a three-dimensional grid. Comparisons to the Pal et al. heat flux data will be made for both RANS and

  19. Spatial and temporal variations in DOM composition in ecosystems: The importance of long-term monitoring of optical properties

    Science.gov (United States)

    R. Jaffe; D. McKnight; N. Maie; R. Cory; W. H. McDowell; J.L. Campbell

    2008-01-01

    Source, transformation, and preservation mechanisms of dissolved organic matter (DOM) remain elemental questions in contemporary marine and aquatic sciences and represent a missing link in models of global elemental cycles. Although the chemical character of DOM is central to its fate in the global carbon cycle, DOM characterizations in long-term ecological research...

  20. The interaction of RNA helicase DDX3 with HIV-1 Rev-CRM1-RanGTP complex during the HIV replication cycle.

    Science.gov (United States)

    Mahboobi, Seyed Hanif; Javanpour, Alex A; Mofrad, Mohammad R K

    2015-01-01

    Molecular traffic between the nucleus and the cytoplasm is regulated by the nuclear pore complex (NPC), which acts as a highly selective channel perforating the nuclear envelope in eukaryotic cells. The human immunodeficiency virus (HIV) exploits the nucleocytoplasmic pathway to export its RNA transcripts across the NPC to the cytoplasm. Despite extensive study on the HIV life cycle and the many drugs developed to target this cycle, no current drugs have been successful in targeting the critical process of viral nuclear export, even though HIV's reliance on a single host protein, CRM1, to export its unspliced and partially spliced RNA transcripts makes it a tempting target. Due to recent findings implicating a DEAD-box helicase, DDX3, in HIV replication and a member of the export complex, it has become an appealing target for anti-HIV drug inhibition. In the present research, we have applied a hybrid computational protocol to analyze protein-protein interactions in the HIV mRNA export cycle. This method is based on molecular docking followed by molecular dynamics simulation and accompanied by approximate free energy calculation (MM/GBSA), computational alanine scanning, clustering, and evolutionary analysis. We highlight here some of the most likely binding modes and interfacial residues between DDX3 and CRM1 both in the absence and presence of RanGTP. This work shows that although DDX3 can bind to free CRM1, addition of RanGTP leads to more concentrated distribution of binding modes and stronger binding between CRM1 and RanGTP.

  1. Origin of the nucleus and Ran-dependent transport to safeguard ribosome biogenesis in a chimeric cell

    Directory of Open Access Journals (Sweden)

    Jékely Gáspár

    2008-07-01

    Full Text Available Abstract Background The origin of the nucleus is a central problem about the origin of eukaryotes. The common ancestry of nuclear pore complexes (NPC and vesicle coating complexes indicates that the nucleus evolved via the modification of a pre-existing endomembrane system. Such an autogenous scenario is cell biologically feasible, but it is not clear what were the selective or neutral mechanisms that had led to the origin of the nuclear compartment. Results A key selective force during the autogenous origin of the nucleus could have been the need to segregate ribosome factories from the cytoplasm where ribosomal proteins (RPs of the protomitochondrium were synthesized. After its uptake by an anuclear cell the protomitochondrium transferred several of its RP genes to the host genome. Alphaproteobacterial RPs and archaebacterial-type host ribosomes were consequently synthesized in the same cytoplasm. This could have led to the formation of chimeric ribosomes. I propose that the nucleus evolved when the host cell compartmentalised its ribosome factories and the tightly linked genome to reduce ribosome chimerism. This was achieved in successive stages by first evolving karyopherin and RanGTP dependent chaperoning of RPs, followed by the evolution of a membrane network to serve as a diffusion barrier, and finally a hydrogel sieve to ensure selective permeability at nuclear pores. Computer simulations show that a gradual segregation of cytoplasm and nucleoplasm via these steps can progressively reduce ribosome chimerism. Conclusion Ribosome chimerism can provide a direct link between the selective forces for and the mechanisms of evolving nuclear transport and compartmentalisation. The detailed molecular scenario presented here provides a solution to the gradual evolution of nuclear compartmentalization from an anuclear stage. Reviewers This article was reviewed by Eugene V Koonin, Martijn Huynen, Anthony M. Poole and Patrick Forterre.

  2. Nuclear-cytoplasmic trafficking of NTF2, the nuclear import receptor for the RanGTPase, is subjected to regulation

    National Research Council Canada - National Science Library

    Chafe, Shawn C; Pierce, Jacqueline B; Mangroo, Dev

    2012-01-01

    .... Treatment of mammalian cells with polysorbitan monolaurate was found to inhibit nuclear export of tRNA and proteins, which are processes dependent on RanGTP in the nucleus, but not nuclear import...

  3. Molecular characteristics of continuously released DOM during one year of root and leaf litter decomposition

    Science.gov (United States)

    Altmann, Jens; Jansen, Boris; Kalbitz, Karsten; Filley, Timothy

    2013-04-01

    Dissolved organic matter (DOM) is one of the most dynamic carbon pools linking the terrestrial with the aquatic carbon cycle. Besides the insecure contribution of terrestrial DOM to the greenhouse effect, DOM also plays an important role for the mobility and availability of heavy metals and organic pollutants in soils. These processes depend very much on the molecular characteristics of the DOM. Surprisingly the processes that determine the molecular composition of DOM are only poorly understood. DOM can originate from various sources, which influence its molecular composition. It has been recognized that DOM formation is not a static process and DOM characteristics vary not only between different carbon sources. However, molecular characteristics of DOM extracts have scarcely been studied continuously over a longer period of time. Due to constant molecular changes of the parent litter material or soil organic matter during microbial degradation, we assumed that also the molecular characteristics of litter derived DOM varies at different stages during root and needle decomposition. For this study we analyzed the chemical composition of root and leaf samples of 6 temperate tree species during one year of litter decomposition in a laboratory incubation. During this long-term experiment we measured continuously carbon and nitrogen contents of the water extracts and the remaining residues, C mineralization rates, and the chemical composition of water extracts and residues by Curie-point pyrolysis mass spectrometry with TMAH We focused on the following questions: (I) How mobile are molecules derived from plant polymers like tannin, lignin, suberin and cutin? (II) How does the composition of root and leaf derived DOM change over time in dependence on the stage of decomposition and species? Litter derived DOM was generally dominated by aromatic compounds. Substituded fatty acids as typically cutin or suberin derived were not detected in the water extracts. Fresh leaf and

  4. Violencia doméstica y exclusión social de mujeres maltratadas en Colombia

    OpenAIRE

    Giraldo Arias, Regina

    2016-01-01

    La presente investigación estudia el fenómeno de la violencia doméstica en Colombia, y propone para el estudio de la complejidad del problema, un abordaje eco-sistémico de la familia y la pareja, en relación con la exclusión social. Se plantearon dos objetivos principales. Primero, analizar los ejes y dimensiones de la exclusión social, en relación con la violencia doméstica en mujeres maltratadas por su compañero sentimental. Segundo, estudiar la relación entre violencia doméstica con perman...

  5. Seasonal changes in the optical properties of dissolved organic matter (DOM) in large Arctic rivers

    DEFF Research Database (Denmark)

    Walker, S.A.; Amon, R.M.; Stedmon, Colin

    Arctic rivers deliver over 10% of the annual global river discharge yet little is known about the seasonal fluctuations in the quantity and quality of terrigenous dissolved organic matter (tDOM). A good constraint on such fluctuations is paramount to understand the role that climate change may have...... on tDOM input to the Arctic Ocean. To understand such changes the optical properties of colored tDOM (tCDOM) were studied. Samples were collected over several seasonal cycles from the six largest Arctic Rivers as part of the PARTNERS project. This unique dataset is the first of its kind capturing...

  6. doméstico. Discusiones y estudios recientes

    Directory of Open Access Journals (Sweden)

    Patricia Arias

    2013-01-01

    Full Text Available Con base en la revisión de algunos estudios recientes que se han llevado a cabo en diver- sas comunidades rurales de las nuevas regiones migratorias, en este artículo se revisan, de manera crítica, dos interpretaciones de los estudios sobre la familia rural: la economía campesina como unidad de producción-consumo y el ciclo de desarrollo de la unidad doméstica. En las condiciones actuales la migración, interna e internacional, desem- peña un papel decisivo en las comunidades rurales. Muchos estudios han constatado la voluntad de las mujeres de salir de los grupos domésticos y sumarse a los flujos migra- torios por motivos particulares, por situaciones y demandas específicas de ellas; su salida ha contribuido al resquebrajamiento de los sistemas tradicionales de organización y re- producción de la familia campesina. Las feministas, y más tarde los estudios con la perspectiva de género, criticaron la visión de que las familias rurales constituían unidades de producción-consumo donde las decisiones correspondían a un modelo de estrategias familiares de sobrevivencia y reproducción (Hondagneu-Sotelo, 2007; Wolf, 1990. Ese modelo privilegiaba la homo- geneidad, la colectividad, la solidaridad y el consenso, es decir, suponía que en los hogares no había conflictos ni tensiones a la hora de tomar decisiones que a todos com- prometían (Ariza, 2007. La familia era una “unidad económica moral” que se susten- taba en los principios de “reciprocidad, consenso y altruismo” (Grasmuck y Pessar, 1991. Los estudios desde el enfoque de género señalaron que en las familias había relacio- nes de poder basadas en una distribución jerárquica y desigual de los derechos, recursos y autoridad que afectaban especialmente a las mujeres (Ariza, 2007; González Montes, 2002; Hondagneu-Sotelo, 2007; Wolf, 1990. Las críticas alcanzaron a los estudios migratorios: la migración no era un fenómeno exclusivamente de los hombres, las mi

  7. Beyond Rab GTPases Legionella activates the small GTPase Ran to promote microtubule polymerization, pathogen vacuole motility, and infection.

    Science.gov (United States)

    Hilbi, Hubert; Rothmeier, Eva; Hoffmann, Christine; Harrison, Christopher F

    2014-01-01

    Legionella spp. are amoebae-resistant environmental bacteria that replicate in free-living protozoa in a distinct compartment, the Legionella-containing vacuole (LCV). Upon transmission of Legionella pneumophila to the lung, the pathogens employ an evolutionarily conserved mechanism to grow in LCVs within alveolar macrophages, thus triggering a severe pneumonia termed Legionnaires' disease. LCV formation is a complex and robust process, which requires the bacterial Icm/Dot type IV secretion system and involves the amazing number of 300 different translocated effector proteins. LCVs interact with the host cell's endosomal and secretory vesicle trafficking pathway. Accordingly, in a proteomics approach as many as 12 small Rab GTPases implicated in endosomal and secretory vesicle trafficking were identified and validated as LCV components. Moreover, the small GTPase Ran and its effector protein RanBP1 have been found to decorate the pathogen vacuole. Ran regulates nucleo-cytoplasmic transport, spindle assembly, and cytokinesis, as well as the organization of non-centrosomal microtubules. In L. pneumophila-infected amoebae or macrophages, Ran and RanBP1 localize to LCVs, and the small GTPase is activated by the Icm/Dot substrate LegG1. Ran activation by LegG1 leads to microtubule stabilization and promotes intracellular pathogen vacuole motility and bacterial growth, as well as chemotaxis and migration of Legionella-infected cells.

  8. The nucleoporin MEL-28 promotes RanGTP-dependent γ-tubulin recruitment and microtubule nucleation in mitotic spindle formation.

    Science.gov (United States)

    Yokoyama, Hideki; Koch, Birgit; Walczak, Rudolf; Ciray-Duygu, Fulya; González-Sánchez, Juan Carlos; Devos, Damien P; Mattaj, Iain W; Gruss, Oliver J

    2014-01-01

    The GTP-bound form of the Ran GTPase (RanGTP), produced around chromosomes, drives nuclear envelope and nuclear pore complex (NPC) re-assembly after mitosis. The nucleoporin MEL-28/ELYS binds chromatin in a RanGTP-regulated manner and acts to seed NPC assembly. Here we show that, upon mitotic NPC disassembly, MEL-28 dissociates from chromatin and re-localizes to spindle microtubules and kinetochores. MEL-28 directly binds microtubules in a RanGTP-regulated way via its C-terminal chromatin-binding domain. Using Xenopus egg extracts, we demonstrate that MEL-28 is essential for RanGTP-dependent microtubule nucleation and spindle assembly, independent of its function in NPC assembly. Specifically, MEL-28 interacts with the γ-tubulin ring complex and recruits it to microtubule nucleation sites. Our data identify MEL-28 as a RanGTP target that functions throughout the cell cycle. Its cell cycle-dependent binding to chromatin or microtubules discriminates MEL-28 functions in interphase and mitosis, and ensures that spindle assembly occurs only after NPC breakdown.

  9. Ivan Rančić: A forgotten painter of flowers and landscapes

    Directory of Open Access Journals (Sweden)

    Marković Kamenko M.

    2014-01-01

    Full Text Available Ivan Rančić was born in the Kraljevo village, in eastern Serbia to a family of farmers on 19th, February, 1906. Very little data about him has been preserved, therefore, this paper is an attempt to make a reconstruction of his life and work. He attended primary school in his birth place, lower secondary school he finished in Knjazevac and Military Academy in Belgrade. After completing the National Academy in 1934, he was sent to Zagreb where he got his first post. He lived there with his wife and his son until the capitulation of the country in 1941. A few months after the collapse of the country, he was arrested and sent to Ljubljana and three months later to a concentration camp in Austria. He spent about fifteen months in that camp in during which time he intensively studied painting. He fled from the camp to Switzerland and stayed there until his death in 1987. According to some letters he sent to his wife in Nis, some of his paintings he created during his time in the camp, ne took to Switzerland where he eventually sold them. He did the toughest jobs there in order to survive and painted extensively. After World War II he graduated from the School of Fine Arts in Lausanne. Later on he had two exhibitions at the New Gallery of Modern Art. Ivan Rančić came a long way from an unknown beginner to a respected prominent artist. He left behind about 350 works, many of which he sold during his life, mainly landscapes and still life in oil, watercolor and pastel. He was neither concerned about styles and trends nor did he believe in the old and the new. If he came to a certain specific manner of painting, it is because at one point it was imposed on him as the only proper way of expression. The analysis of Rančić's paintings leads to the conclusion that his creation had gone through four phases. The first one (started in the concentration camp in Austria during which he painted still lifes without full sketches, previous studies, and the use

  10. İRAN VE REJİM İSTİKRARI

    Directory of Open Access Journals (Sweden)

    Özgür ÜŞENMEZ

    2015-07-01

    Full Text Available ÖZ: Bu çalışma, İran rejiminin son yıllarda Orta Doğu'yu sarsan isyanlar ve istikrarsızlıklara-Batı'daki beklentilerin aksine- geçmişten, özellikle 1979'daki devrimden miras kalan sosyal yapı ve politikaların etkisiyle direnebildiğini iddia ediyor. Tunus ve Mısır'daki halk isyanları, temel aktör olan alt sınıflar ve onların neo-liberal ekonomik politikalara muhalefetiyle yayılırken, İran’da devrim sonrası gelişen sosyal devlet mekanizması hala halk ile rejimin tamamen birbirine yabancılaşmasını önlemekte. Ancak son yıllarda ortaya çıkan yeni gerilimler ve İran'ın uyguladığı ekonomi politikaları rejimin krizini derinleştirebilir. Bu nedenledir ki Orta Doğu'yu ve özelde İran'ı anlamak için hegemonik blokların tarihsel değişimini inceleyen ucu açık bir analiz elzemdir. ABSTRACT: This article argues that contrary to the expectations of the Western World, Iranian regime successfully resisted the revolutionary tides of the Arab Spring. Most important determinant of this process for Iran was the legacy of the 1979 revolution and it's associated structures that relatively protects the most vulnerable parts of the population against the wide spread neo-liberal economic policies in the Middle East. So with that feature Iran differs from the Tunisian and the Egyptian examples. In order to understand these features further this essay adapts a historical analysis of changes in hegemonic blocs in Iran since 1979.

  11. Removal of triazine-based pollutants from water by carbon nanotubes: Impact of dissolved organic matter (DOM) and solution chemistry.

    Science.gov (United States)

    Engel, Maya; Chefetz, Benny

    2016-12-01

    Adsorption of organic pollutants by carbon nanotubes (CNTs) in the environment or removal of pollutants during water purification require deep understanding of the impacts of the presence of dissolved organic matter (DOM). DOM is an integral part of environmental systems and plays a key role affecting the behavior of organic pollutants. In this study, the effects of solution chemistry (pH and ionic strength) and the presence of DOM on the removal of atrazine and lamotrigine by single-walled CNTs (SWCNTs) was investigated. The solubility of atrazine slightly decreased (∼5%) in the presence of DOM, whereas that of lamotrigine was significantly enhanced (by up to ∼70%). Simultaneous introduction of DOM and pollutant resulted in suppression of removal of both atrazine and lamotrigine, which was attributed to DOM-pollutant competition or blockage of adsorption sites by DOM. However the decrease in removal of lamotrigine was also a result of its complexation with DOM. Pre-introduction of DOM significantly reduced pollutant adsorption by the SWCNTs, whereas introduction of DOM after the pollutant resulted in the release of adsorbed atrazine and lamotrigine from the SWCNTs. These data imply that DOM exhibits higher affinity for the adsorption sites than the triazine-based pollutants. In the absence of DOM atrazine was a more effective competitor than lamotrigine for adsorption sites in SWCNTs. However, competition between pollutants in the presence of DOM revealed lamotrigine as the better competitor. Our findings help unravel the complex DOM-organic pollutant-CNT system and will aid in CNT-implementation in water-purification technologies. Copyright © 2016 Elsevier Ltd. All rights reserved.

  12. Is DOM driver of the microbial carrying capacity in pristine porous groundwater ecosystems? - lab-scale experiments in 2D sediment flow-through microcosms

    Science.gov (United States)

    Hofmann, Roland; Griebler, Christian

    2017-04-01

    Groundwater ecosystems are an essential resource for drinking water and at the same time constitute fascinating habitats subject to increasing (anthropogenic) disturbances. In our research, we look for ways to qualitatively and quantitatively access, and predict the resistance and resilience (potential) of groundwater ecosystems in consequence of selected disturbances. As a central goal we hope to identify and quantify the underlying biological and ecological key drivers of the microbial Carrying Capacity (mCC) - an ecological concept established in macro-ecology - we assume directly connected to the ecosystem's productivity and the resistance and resilience of aquifers. We further hypothesize, that the ecosystems' mCC is a result of available energy and constitutes a promising proxy for the potential of groundwater ecosystems to withstand impacts and recover from it. In a first approach we studied the dynamics of the microbial standing stock (biomass) and growth (productivity) productivity of a natural groundwater microbial community in parallel 2-D sediment flow-through systems. Selected zones of the model aquifers were disturbed by elevated DOM concentrations. Both the 'mobile' (free floating) and 'sessile' (sediment attached) microbial components were followed over time in terms of biomass, growth, and specific activities (ATP, carbon use efficiency) and taxonomic composition. Sediment regions supplied with elevated concentrations of natural DOM showed increased biomass, activities and taxonomic richness with the sediment community, while differences in the mobile microbial were marginal. Specifically, the carbon use efficiency was significantly increased in the DOM amended sediment zones. In contrast, the microbial community that received the mainly refractory natural background DOM was able to metabolize polymers more efficiently in substrate use tests (ECOLOG), seen as an adaptation to the energy-poor subsurface. Quasi-stationary conditions were reached in

  13. Colegio de oficios domésticos. Manchester

    Directory of Open Access Journals (Sweden)

    Howitt, Leonard G.

    1965-05-01

    Full Text Available The unit closest to Wimslow Road has two storeys, interconnected. The unit closest to Wimslow Road has two storeys, and is U shaped. It is occupied by the director's office and other administrative rooms, and also by space devoted to the students social life, such as dining room, hall, and lounges. To the east, the tallest of the three buildings is taken up with the lecture rooms, laboratories, and other training faculties. Still further to the east, the third unit, which has only one storey, accommodates the tailoring and dressmaking department. On the north side a gymnasium provides sporting facilities for all the students.Ese complejo escolar consta de tres unidades principales debidamente conectadas. La unidad de dos plantas—más cercana a Wilmslow Road—, en forma de U aloja, además de los despachos de dirección y administración, las áreas dedicadas a «vida social» de los estudiantes, comedor, salón de actos, etc. Inmediatamente al E. se alza el edificio más elevado del conjunto, que contiene una serie de aulas, laboratorios, etc., en donde se desarrollan las enseñanzas de las Artes domésticas. Al E. del edificio anterior hay un bloque de una sola planta, destinado a la enseñanza de sastrería, etc.; e inmediatamente al N. se encuentra el gimnasio que sirve a los estudiantes de todos los departamentos.

  14. El consumo doméstico en comunidades migrantes

    Directory of Open Access Journals (Sweden)

    Renato Salas Alfaro

    2007-06-01

    Full Text Available En este trabajo se construye una función de consumo doméstico en una comunidad rural. Se muestra que una función tal, en este escenario recibe efectos de variables económicas como los ingresos corrientes, las remesas internacionales y la riqueza que posee el hogar (valor total de sus activos, corroborando de este modo el planteamiento teórico de la hipótesis del ciclo vital y de la teoría keynesiana. No obstante la función derivada sugiere que en una comunidad indígena, los aspectos culturales siguen teniendo un peso importante; ésta recibe con bastante intensidad efectos de la forma en que un hogar financia su migración, las hectáreas de tierra que abandona de la producción y de la propia PEA, variables que no captura ninguno de los planteamientos referidos.

  15. Dom-kommuna: Housing experiment of Russian constructivism

    Directory of Open Access Journals (Sweden)

    Bajić Tanja

    2010-01-01

    Full Text Available Dom-kommuna is original historic concept of collective social housing for whose formation is responsible comprehensive architectural research of Soviet constructivists during the 1920s and 1930s. This housing model did not only emerge as a necessary response to the great housing crisis, but as a 'new social condenser' of the era, which was supposed to contribute to the accelerated social progress of Soviet Union on the basis of Marxist ideology, according to the deep conviction of their authors. Housing commune was created as a specific spatial framework for the abolition of class antagonisms and different life forms of the bourgeoisie and the proletariat, for the encouragement of collectivization, women's emancipation and reduction of the impact of nuclear family. In this paper some of the basic elements of the creative research of Russian constructivists, with aim to establish a new housing prototype, are analyzed and abstracted. The interpretation of the creative process through simulation of its main creative phase focuses on the process of socialist transformation of the idea of living based on the vision of 'reconstruction' and the principles of functionalism. This paper is intended to indicate the rationality and the complexity of the architectural considerations of the minimum living space in constructivism, whose results, such as the F-type residential unit, can be considered as universal contribution to residential architecture and a model which deserves contemporary architectural interpretation, despite being initiated by ideological demands.

  16. OTN Transport of Baseband Radio Serial Protocols in C-RAN Architecture for Mobile Network Applications

    DEFF Research Database (Denmark)

    Checko, Aleksandra; Kardaras, Georgios; Lanzani, Christian Fabio Alessandro

    This white paper presents a proof of concept implementation of digital baseband radio data transport over Optical Transport Network (OTN) compliant to 3GPP Long Term Evolution – Advanced (LTE-A) standard enabling Cloud Radio Access Network (C-RAN) architecture. The transport between the baseband...... module and a remote radio module is compliant to Common Public Radio Interface (CPRI) and to the OBSAI reference point 3 - 01 (RP3-01) interface protocols, respectively. The purpose is to demonstrate that data integrity and clocking performance at the radio node still meets the strict standard...

  17. Investigation on hydrodynamic performance of a marine propeller in oblique flow by RANS computations

    Directory of Open Access Journals (Sweden)

    Jianxi Yao

    2015-01-01

    Full Text Available This paper presents a numerical study on investigating on hydrodynamic characteristics of a marine propeller in oblique flow. The study is achieved by RANS simulations on an open source platform - OpenFOAM. A sliding grid approach is applied to compute the rotating motion of the propeller. Total force and moment acting on blades, as well as average force distributions in one revolution on propeller disk, are obtained for 70 cases of com- binations of advance ratios and oblique angles. The computed results are compared with available experimental data and discussed.

  18. Hybrid RANS/LES method for wind flow over complex terrain

    DEFF Research Database (Denmark)

    Bechmann, Andreas; Sørensen, Niels N.

    2010-01-01

    ), and this layer acts as wall model for the outer flow handled by LES. The well-known high Reynolds number two-equation k - turbulence model is used in the RANS layer and the model automatically switches to a two-equation k - subgrid scale stress model in the LES region. The approach can be used for flow over...... the turbulent kinetic energy, whereas the new method captures the high turbulence levels well but underestimates the mean velocity. The presented results are for a relative mild configuration of complex terrain, but the proposed method can also be used for highly complex terrain where the benefits of the new...

  19. Statistical Multiplexing of Computations in C-RAN with Tradeoffs in Latency and Energy

    DEFF Research Database (Denmark)

    Kalør, Anders Ellersgaard; Agurto Agurto, Mauricio Ignacio; Pratas, Nuno

    2017-01-01

    In the Cloud Radio Access Network (C-RAN) architecture, the baseband signals from multiple remote radio heads are processed in a centralized baseband unit (BBU) pool. This architecture allows network operators to adapt the BBU’s computational resources to the aggregate access load experienced...... frame duration, then this may result in additional access latency and limit the energy savings. In this paper we investigate the tradeoff by considering two extreme time-scales for the resource multiplexing: (i) long-term, where the computational resources are adapted over periods much larger than...

  20. Synchronization challenges in packet-based Cloud-RAN fronthaul for mobile networks

    DEFF Research Database (Denmark)

    Checko, Aleksandra; Juul, Anders Christian; Christiansen, Henrik Lehrmann

    2015-01-01

    In this paper, we look at reusing existing packet-based network (e.g. Ethernet) to possibly decrease deployment costs of fronthaul Cloud Radio Access Network (C-RAN) network and cost of Baseband Unit (BBU) resources. The challenge of this solution is that it requires mobile traffic (until now...... transmitted over synchronous protocols) to traverse the asynchronous Ethernet without losing synchronization. We analyze synchronization requirements of mobile networks and present an overview of solutions that fulfill them in traditional mobile networks. Then we elaborate on challenges that packet...... bridge the gap between Ethernet and mobile network domains creating a comprehensive architectural analysis....

  1. Ran Involved in the Development and Reproduction Is a Potential Target for RNA-Interference-Based Pest Management in Nilaparvata lugens.

    Directory of Open Access Journals (Sweden)

    Kai-Long Li

    Full Text Available Ran (RanGTPase in insects participates in the 20-hydroxyecdysone signal transduction pathway in which downstream genes, FTZ-F1, Krüppel-homolog 1 (Kr-h1 and vitellogenin, are involved. A putative Ran gene (NlRan was cloned from Nilaparvata lugens, a destructive phloem-feeding pest of rice. NlRan has the typical Ran primary structure features that are conserved in insects. NlRan showed higher mRNA abundance immediately after molting and peaked in newly emerged female adults. Among the examined tissues ovary had the highest transcript level, followed by fat body, midgut and integument, and legs. Three days after dsNlRan injection the NlRan mRNA abundance in the third-, fourth-, and fifth-instar nymphs was decreased by 94.3%, 98.4% and 97.0%, respectively. NlFTZ-F1 expression levels in treated third- and fourth-instar nymphs were reduced by 89.3% and 23.8%, respectively. In contrast, NlKr-h1 mRNA levels were up-regulated by 67.5 and 1.5 folds, respectively. NlRan knockdown significantly decreased the body weights, delayed development, and killed >85% of the nymphs at day seven. Two apparent phenotypic defects were observed: (1 Extended body form, and failed to molt; (2 The cuticle at the notum was split open but cannot completely shed off. The newly emerged female adults from dsNlRan injected fifth-instar nymphs showed lower levels of NlRan and vitellogenin, lower weight gain and honeydew excretion comparing with the blank control, and no offspring. Those results suggest that NlRan encodes a functional protein that was involved in development and reproduction. The study established proof of concept that NlRan could serve as a target for dsRNA-based pesticides for N. lugens control.

  2. First results of the KM3NeT multi-PMT DOM

    Energy Technology Data Exchange (ETDEWEB)

    Michael, Tino [Nikhef - National Institute for Subatomic Physics, Science Park 105, 1098 XG Amsterdam (Netherlands); Collaboration: KM3NeT Collaboration

    2014-11-18

    The future KM3NeT neutrino telescope will consist of several thousand digital optical modules (DOMs), each of which will be equipped with 31 3-inch photo-multiplier tubes (PMTs). This design has various advantages over the use of one large PMT per optical module, e.g. concerning effective photocathode area per module, improved background suppression and directional reconstruction. Currently, the KM3NeT collaboration is testing a prototype DOM deployed on the instrumentation line of the ANTARES neutrino telescope. The DOM has been operational since mid-April 2013. First data are presented and compared to simulation results. The results are very encouraging and indicate that muon identification and a coarse direction estimation are possible event with a single DOM.

  3. Tracing dissolved organic matter (DOM) from land-based aquaculture systems in North Patagonian streams

    DEFF Research Database (Denmark)

    Nimptsch, Jorge; Woelfl, Stefan; Osorio, Sebastian

    2015-01-01

    Chile is the second largest producer of salmonids worldwide. The first step in the production of salmonids takes place in land-based aquacultures. However, the effects of the discharge from these aquacultures on stream dissolved organic matter (DOM) content, molecular composition and degradability...... and tryptophan) released from fish feces and food remains, and that ii) this DOM is highly degradable and therefore rapidly turned-over within the receiving streams. In the North Patagonian region we conducted a screening of ten land-based aquacultures and an intensive sampling campaign for one aquaculture....... This was combined with longitudinal transects and a degradation experiment in order to couple the composition of DOM exported from land-based aquacultures to its degradability in streams. We measured dissolved organic carbon (DOC) concentration by high-temperature catalytic oxidation and DOM composition...

  4. DomPep--a general method for predicting modular domain-mediated protein-protein interactions.

    Directory of Open Access Journals (Sweden)

    Lei Li

    Full Text Available Protein-protein interactions (PPIs are frequently mediated by the binding of a modular domain in one protein to a short, linear peptide motif in its partner. The advent of proteomic methods such as peptide and protein arrays has led to the accumulation of a wealth of interaction data for modular interaction domains. Although several computational programs have been developed to predict modular domain-mediated PPI events, they are often restricted to a given domain type. We describe DomPep, a method that can potentially be used to predict PPIs mediated by any modular domains. DomPep combines proteomic data with sequence information to achieve high accuracy and high coverage in PPI prediction. Proteomic binding data were employed to determine a simple yet novel parameter Ligand-Binding Similarity which, in turn, is used to calibrate Domain Sequence Identity and Position-Weighted-Matrix distance, two parameters that are used in constructing prediction models. Moreover, DomPep can be used to predict PPIs for both domains with experimental binding data and those without. Using the PDZ and SH2 domain families as test cases, we show that DomPep can predict PPIs with accuracies superior to existing methods. To evaluate DomPep as a discovery tool, we deployed DomPep to identify interactions mediated by three human PDZ domains. Subsequent in-solution binding assays validated the high accuracy of DomPep in predicting authentic PPIs at the proteome scale. Because DomPep makes use of only interaction data and the primary sequence of a domain, it can be readily expanded to include other types of modular domains.

  5. Characterization of the discriminative stimulus properties of centrally administered (-)-DOM and LSD.

    Science.gov (United States)

    Doat, Mireille M; Rabin, Richard A; Winter, Jerrold C

    2003-02-01

    Despite the plausible assumption that the effects of hallucinogens predominantly arise in the central nervous system, most studies of these drugs in intact subjects have been conducted following systemic administration. The objective of the present investigation was to characterize the stimulus effects of (-)2,5-dimethoxy-4-methylamphetamine ((-)-DOM) following intracerebroventricular administration. Chronic indwelling cannulae were implanted into the lateral ventricle of male Fischer 344 rats trained to discriminate systemically administered (-)-DOM or lysergic acid diethylamide (LSD) from saline. Time-course and dose-response relationships for (-)-DOM and LSD administered intracerebroventricularly were established. For both LSD and (-)-DOM, central administration did not change the pretreatment times required for the maximal stimulus effects to occur. However, the onset of the stimulus effect was more rapid following intracerebroventricular administration. Following pretreatment periods that maximize drug-appropriate responding, central administration of (-)-DOM and LSD was approximately 2.4- and 1.5-times more potent, respectively, than systemic administration. The results of this study are consistent with the assumption that the stimulus effects of (-)-DOM and LSD are centrally mediated.

  6. Canoe binds RanGTP to promote PinsTPR/Mud-mediated spindle orientation

    Science.gov (United States)

    Wee, Brett; Johnston, Christopher A.

    2011-01-01

    Regulated spindle orientation maintains epithelial tissue integrity and stem cell asymmetric cell division. In Drosophila melanogaster neural stem cells (neuroblasts), the scaffolding protein Canoe (Afadin/Af-6 in mammals) regulates spindle orientation, but its protein interaction partners and mechanism of action are unknown. In this paper, we use our recently developed induced cell polarity system to dissect the molecular mechanism of Canoe-mediated spindle orientation. We show that a previously uncharacterized portion of Canoe directly binds the Partner of Inscuteable (Pins) tetratricopeptide repeat (TPR) domain. The Canoe–PinsTPR interaction recruits Canoe to the cell cortex and is required for activation of the PinsTPR-Mud (nuclear mitotic apparatus in mammals) spindle orientation pathway. We show that the Canoe Ras-association (RA) domains directly bind RanGTP and that both the CanoeRA domains and RanGTP are required to recruit Mud to the cortex and activate the Pins/Mud/dynein spindle orientation pathway. PMID:22024168

  7. Comparisons of LES and RANS Computations with PIV Experiments on a Cylindrical Cavity Flow

    Directory of Open Access Journals (Sweden)

    Wen-Tao Su

    2013-01-01

    Full Text Available A comparison study on the numerical computations by large eddy simulation (LES and Reynolds-averaged Navier-Stokes (RANS methods with experiment on a cylindrical cavity flow was conducted in this paper. Numerical simulations and particle image velocimetry (PIV measurement were performed for two Reynolds numbers of the flow at a constant aspect ratio of H/R = 2.4 (R is the radius of the cylindrical cavity, and H is liquid level. The three components of velocity were extracted from 100 sequential PIV measured velocity frames with averaging, in order to illustrate the axial jet flow evolution and circulation distribution in the radial direction. The results show that LES can reproduce well the fine structure inside the swirling motions in both the meridional and the horizontal planes, as well as the distributions of velocity components and the circulation, in good agreement with experimental results, while the RANS method only provided a rough trend of inside vortex structure. Based on the analysis of velocity profiles at various locations, it indicates that LES is more suitable for predicting the complex flow characteristics inside complicated three-dimensional geometries.

  8. Validation of Heat Transfer and Film Cooling Capabilities of the 3-D RANS Code TURBO

    Science.gov (United States)

    Shyam, Vikram; Ameri, Ali; Chen, Jen-Ping

    2010-01-01

    The capabilities of the 3-D unsteady RANS code TURBO have been extended to include heat transfer and film cooling applications. The results of simulations performed with the modified code are compared to experiment and to theory, where applicable. Wilcox s k-turbulence model has been implemented to close the RANS equations. Two simulations are conducted: (1) flow over a flat plate and (2) flow over an adiabatic flat plate cooled by one hole inclined at 35 to the free stream. For (1) agreement with theory is found to be excellent for heat transfer, represented by local Nusselt number, and quite good for momentum, as represented by the local skin friction coefficient. This report compares the local skin friction coefficients and Nusselt numbers on a flat plate obtained using Wilcox's k-model with the theory of Blasius. The study looks at laminar and turbulent flows over an adiabatic flat plate and over an isothermal flat plate for two different wall temperatures. It is shown that TURBO is able to accurately predict heat transfer on a flat plate. For (2) TURBO shows good qualitative agreement with film cooling experiments performed on a flat plate with one cooling hole. Quantitatively, film effectiveness is under predicted downstream of the hole.

  9. Development of a Hybrid RANS/LES Method for Turbulent Mixing Layers

    Science.gov (United States)

    Georgiadis, Nicholas J.; Alexander, J. Iwan D.; Reshotko, Eli

    2001-01-01

    Significant research has been underway for several years in NASA Glenn Research Center's nozzle branch to develop advanced computational methods for simulating turbulent flows in exhaust nozzles. The primary efforts of this research have concentrated on improving our ability to calculate the turbulent mixing layers that dominate flows both in the exhaust systems of modern-day aircraft and in those of hypersonic vehicles under development. As part of these efforts, a hybrid numerical method was recently developed to simulate such turbulent mixing layers. The method developed here is intended for configurations in which a dominant structural feature provides an unsteady mechanism to drive the turbulent development in the mixing layer. Interest in Large Eddy Simulation (LES) methods have increased in recent years, but applying an LES method to calculate the wide range of turbulent scales from small eddies in the wall-bounded regions to large eddies in the mixing region is not yet possible with current computers. As a result, the hybrid method developed here uses a Reynolds-averaged Navier-Stokes (RANS) procedure to calculate wall-bounded regions entering a mixing section and uses a LES procedure to calculate the mixing-dominated regions. A numerical technique was developed to enable the use of the hybrid RANS-LES method on stretched, non-Cartesian grids. With this technique, closure for the RANS equations is obtained by using the Cebeci-Smith algebraic turbulence model in conjunction with the wall-function approach of Ota and Goldberg. The LES equations are closed using the Smagorinsky subgrid scale model. Although the function of the Cebeci-Smith model to replace all of the turbulent stresses is quite different from that of the Smagorinsky subgrid model, which only replaces the small subgrid turbulent stresses, both are eddy viscosity models and both are derived at least in part from mixing-length theory. The similar formulation of these two models enables the RANS

  10. Ran GTPase-activating protein 1 is a therapeutic target in diffuse large B-cell lymphoma.

    Directory of Open Access Journals (Sweden)

    Kung-Chao Chang

    Full Text Available Lymphoma-specific biomarkers contribute to therapeutic strategies and the study of tumorigenesis. Diffuse large B-cell lymphoma (DLBCL is the most common type of malignant lymphoma. However, only 50% of patients experience long-term survival after current treatment; therefore, developing novel therapeutic strategies is warranted. Comparative proteomic analysis of two DLBCL lines with a B-lymphoblastoid cell line (LCL showed differential expression of Ran GTPase-activating protein 1 (RanGAP1 between them, which was confirmed using immunoblotting. Immunostaining showed that the majority of DLBCLs (92%, 46/50 were RanGAP1(+, while reactive lymphoid hyperplasia (n = 12 was RanGAP1(+ predominantly in germinal centers. RanGAP1 was also highly expressed in other B-cell lymphomas (BCL, n = 180 with brisk mitotic activity (B-lymphoblastic lymphoma/leukemia: 93%, and Burkitt lymphoma: 95% or cell-cycle dysregulation (mantle cell lymphoma: 83%, and Hodgkin's lymphoma 91%. Interestingly, serum RanGAP1 level was higher in patients with high-grade BCL (1.71 ± 2.28 ng/mL, n = 62 than in low-grade BCL (0.75 ± 2.12 ng/mL, n = 52 and healthy controls (0.55 ± 1.58 ng/mL, n = 75 (high-grade BCL vs. low-grade BCL, p = 0.002; high-grade BCL vs. control, p < 0.001, Mann-Whitney U test. In vitro, RNA interference of RanGAP1 showed no effect on LCL but enhanced DLBCL cell death (41% vs. 60%; p = 0.035 and cell-cycle arrest (G0/G1: 39% vs. 49%, G2/M: 19.0% vs. 7.5%; p = 0.030 along with decreased expression of TPX2 and Aurora kinases, the central regulators of mitotic cell division. Furthermore, ON 01910.Na (Estybon, a multikinase inhibitor induced cell death, mitotic cell arrest, and hyperphosphorylation of RanGAP1 in DLBCL cell lines but no effects in normal B and T cells. Therefore, RanGAP1 is a promising marker and therapeutic target for aggressive B-cell lymphoma, especially DLBCL.

  11. Nuclear-cytoplasmic trafficking of NTF2, the nuclear import receptor for the RanGTPase, is subjected to regulation.

    Directory of Open Access Journals (Sweden)

    Shawn C Chafe

    Full Text Available NTF2 is a cytosolic protein responsible for nuclear import of Ran, a small Ras-like GTPase involved in a number of critical cellular processes, including cell cycle regulation, chromatin organization during mitosis, reformation of the nuclear envelope following mitosis, and controlling the directionality of nucleocytoplasmic transport. Herein, we provide evidence for the first time that translocation of the mammalian NTF2 from the nucleus to the cytoplasm to collect Ran in the GDP form is subjected to regulation. Treatment of mammalian cells with polysorbitan monolaurate was found to inhibit nuclear export of tRNA and proteins, which are processes dependent on RanGTP in the nucleus, but not nuclear import of proteins. Inhibition of the export processes by polysorbitan monolaurate is specific and reversible, and is caused by accumulation of Ran in the cytoplasm because of a block in translocation of NTF2 to the cytoplasm. Nuclear import of Ran and the nuclear export processes are restored in polysorbitan monolaurate treated cells overproducing NTF2. Moreover, increased phosphorylation of a phospho-tyrosine protein and several phospho-threonine proteins was observed in polysorbitan monolaurate treated cells. Collectively, these findings suggest that nucleocytoplasmic translocation of NTF2 is regulated in mammalian cells, and may involve a tyrosine and/or threonine kinase-dependent signal transduction mechanism(s.

  12. Pain-evoked trunk muscle activity changes during fatigue and DOMS.

    Science.gov (United States)

    Larsen, L H; Hirata, R P; Graven-Nielsen, T

    2017-05-01

    Muscle pain may reorganize trunk muscle activity but interactions with exercise-related muscle fatigue and delayed onset muscle soreness (DOMS) is to be clarified. In 19 healthy participants, the trunk muscle activity during 20 multi-directional unpredictable surface perturbations were recorded after bilateral isotonic saline injections (control) and during unilateral and bilateral hypertonic saline-induced low back pain (LBP) in conditions of back muscle fatigue (Day-1) and DOMS (Day-2). Pain intensity and distribution were assessed by visual analogue scale (VAS) scores and pain drawings. The degree of fatigue and DOMS were assessed by Likert scale scores. Root-mean-square electromyographic (RMS-EMG) signals were recorded post-perturbation from six bilateral trunk muscles and the difference from baseline conditions (Delta-RMS-EMG) was extracted and averaged across abdominal and back muscles. In DOMS, peak VAS scores were higher during bilateral control and bilateral saline-induced pain than fatigue (p fatigue (p fatigue and DOMS, the back muscle Delta-RMS-EMG increased during bilateral compared with unilateral pain and control injections (p fatigue, the post-perturbation Delta-RMS-EMG in back muscles was higher during bilateral pain and lower during unilateral pain (p muscle responses to surface perturbations in bilateral and unilateral LBP, respectively, was more expressed during exercise-induced back muscle soreness compared with fatigue. Back muscle activity decreased during unilateral and increased during bilateral pain after unpredictable surface perturbations during muscle fatigue and DOMS. Accumulation effects of DOMS on pain intensity and spreading and trunk muscle activity after pain-induction. © 2017 European Pain Federation - EFIC®.

  13. Persepsi Masyarakat terhadap Pengelolaan Sampah Padat Perkotaan di Kecamatan Dom Aleixo Kabupaten Dili-Timor Leste

    Directory of Open Access Journals (Sweden)

    João Carlos Soares

    2016-10-01

    dalam usaha pemberdayaan, penguatan dan fasilitasi masyarakat melalui pendidikan non formal, penyuluhan, pendampingan dan pengembangan program 3R (reuse, reduce dan recycling guna meningkatkan persepsi masyarakat terhadap pengelolaan sampah rumah tangganya, (b sebagai model dalam merumuskan kebijakan dan aturan daerah guna meningkatkan persepsi masyarakat terhadap pengelolaan sampah padat perkotaan, (c sebagai masukan untuk pemerintah pusat dalam menentukan intansi pengelola sampah perkotaan guna meningkatkan persepsi masyarakat terhadap kinerja Pemkot Dili, (d sebagai masukan untuk pemerintah kota Dili dalam melibatkan peranan stakeholder terhadap kegiatan pengelolaan sampah perkotaan di Kota Dili.    ABSTRACT A case study regarding to public perception of municipal solid waste management in Sub District Dom Aleixo, Dili Timor Leste with a sample of research is household in the village of Comoro and Bairopite.  This research was conducted with the aim to: (1 to assess the public perception of the government's effort to empowering, strengthening and how to facilitate public participation in managing their household waste; (2 to assess the weaknesses and problems faced by the local government of Dili city in terms of: (a formulation of policies and regulations draft about municipal solid waste management in Sub district Dom Aleixo; (b how local government to encourage mobilization of community to participate actively in the activities of the household waste management; (3 to review the institutional structure government of Dili city to reinforce the institution of delegations of urban waste management; (4 to help facilitate the involvement of stakeholders in supporting the government's program on urban waste management in the Dili district.These researches represent the researches which refer to the activity of field or survey. From existing population selected by a number of samples base on sampling technique that is by random sampling. The reason why to choice the

  14. Physics-Informed Machine Learning for Predictive Turbulence Modeling: Using Data to Improve RANS Modeled Reynolds Stresses

    CERN Document Server

    Wang, Jian-Xun; Xiao, Heng

    2016-01-01

    Turbulence modeling is a critical component in numerical simulations of industrial flows based on Reynolds-averaged Navier-Stokes (RANS) equations. However, after decades of efforts in the turbulence modeling community, universally applicable RANS models with predictive capabilities are still lacking. Recently, data-driven methods have been proposed as a promising alternative to the traditional approaches of turbulence model development. In this work we propose a data-driven, physics-informed machine learning approach for predicting discrepancies in RANS modeled Reynolds stresses. The discrepancies are formulated as functions of the mean flow features. By using a modern machine learning technique based on random forests, the discrepancy functions are first trained with benchmark flow data and then used to predict Reynolds stresses discrepancies in new flows. The method is used to predict the Reynolds stresses in the flow over periodic hills by using two training flow scenarios of increasing difficulties: (1) ...

  15. GTPase Ran strongly accumulates at the kinetochores of somatic chromosomes in the spermatogonial mitoses of Acricotopus lucidus (Diptera, Chironomidae).

    Science.gov (United States)

    Staiber, Wolfgang

    2014-07-01

    Unequal chromosome segregation and spindle formation occurs in the last gonial mitosis in the germ line of the chironomid Acricotopus lucidus. During this differential mitosis, all germ line-limited chromosomes (=Ks) migrate undivided to only one pole of the cell, while the somatic chromosomes (=Ss) first remain in the metaphase plane, and with the arrival of the Ks at the pole, they then separate equally. The evolutionarily conserved GTPase Ran plays a crucial role in many cellular processes. This includes the regulation of microtubule nucleation and stabilisation at kinetochores and of spindle assembly during mitosis, which is promoted by a RanGTP concentration gradient that forms around the mitotic chromosomes (Kalab et al. in Science 295:2452-2456, 2002, Nature 440:697-701, 2006). In the present study, a strong accumulation of Ran was detected by immunofluorescence at the kinetochores of the Ss in normal gonial and differential gonial mitoses of males of A. lucidus. In contrast, no Ran accumulation was observed at the kinetochores of the Ss in the metaphases of brain ganglia mitoses or of aberrant spermatocytes or in metaphases I and II of spermatocyte meiotic divisions. Likewise, there was no accumulation at the kinetochores of Drosophila melanogaster mitotic chromosomes from larval brains. The specific accumulation of Ran at the kinetochores of the Ss in differential gonial mitoses of A. lucidus strongly suggests that Ran is involved in a mechanism acting in this exceptional mitosis, which retains the Ss at the metaphase plane and prevents a premature separation and unequal segregation of the Ss during monopolar migration of the Ks.

  16. Rinfoform Usage As Update Request Media Articles In iRAN

    Directory of Open Access Journals (Sweden)

    Untung Rahardja

    2016-10-01

    Full Text Available Ease of access to information made public should continue to improve his knowledge of information technology. As one of the Universities in the field of computers, Perguruan Tinggi Raharja has a lot of innovation to create pembelajalan unconventional media. For that create an information media that serve as a center of tutorial every innovation in Perguruan Tinggi Raharja. iRAN (iLeraning Prog Ask And News. In the implementation one that is still seen as less is a service request in Iran. Utilization of Cloud Computing RinfoApps as media RinfoForms one of them is deemed to cover deficiencies that affect the improvements in the services provided.This research was conducted using the method of data collection, including the method of observation, and literature study method. RinfoForm expected utilization associated with Cluod Computin can give effect to the service request is in Iran.

  17. RANS-based simulation of wave-induced sheet-flow transport of graded sediments

    DEFF Research Database (Denmark)

    Calistan, Ugur; Fuhrman, David R.

    2017-01-01

    A one-dimensional vertical (1DV) turbulence-closure flow model, coupled with sediment transport capabilities,is extended to incorporate graded sediment mixtures. The hydrodynamic model solves the horizontalcomponent of the incompressible Reynolds-averaged Navier–Stokes (RANS) equations coupled...... for each grain fraction, includingeffects associated with increased exposure of larger particles within a mixture. The suspended sedimenttransport model also makes use of modified reference concentration approach, wherein reference concentrationscomputed individually for each fraction are translated...... to a common level, conveniently enabling use of asingle computational grid for the simulation of suspended sediments. Parametric study shows that these twoeffects combine to help alleviate an otherwise systematic tendency towards over- (under-) predicted transportrates for fine (coarse) sand fractions...

  18. Rans-Based Numerical Simulation of Wave-Induced Sheet-Flow Transport of Graded Sediments

    DEFF Research Database (Denmark)

    Fuhrman, David R.; Caliskan, Ugur

    An existing one-dimensional vertical (1DV) turbulence-closure flow model, coupled with sediment transport capabilities, is extended to incorporate graded sediment mixtures. The hydrodynamic model solves the horizontal component of the incompressible Reynolds-averaged Navier–Stokes (RANS) equations...... coupled with k–ω turbulence closure. In addition to standard bed and suspended load descriptions, the sediment transport model incorporates so-called high-concentration effects (turbulence damping and hindered settling velocities). The sediment transport model treats the bed and suspended load...... individually for each grain fraction within a mixture, and includes effects associated with increased exposure of larger particles within a mixture. The model also makes use of a modified reference concentration approach, with reference concentrations computed individually for each fraction...

  19. RANS-based simulation of turbulent wave boundary layer and sheet-flow sediment transport processes

    DEFF Research Database (Denmark)

    Fuhrman, David R.; Schløer, Signe; Sterner, Johanna

    2013-01-01

    A numerical model coupling the horizontal component of the incompressible Reynolds-averaged Navier–Stokes (RANS) equationswith two-equation k−ω turbulence closure is presented and used to simulate a variety of turbulent wave boundary layer processes. The hydrodynamic model is additionally coupled...... of a number of local factors important within cross-shore wave boundary layer and sediment transport dynamics. The hydrodynamic model is validated for both hydraulically smooth and rough conditions, based on wave friction factor diagrams and boundary layer streaming profiles, with the results in excellent...... agreement with experimental and/or previous numerical work. The sediment transport model is likewise validated against oscillatory tunnel experiments involving both velocity-skewed and acceleration-skewed flows, as well as against measurements beneath real progressive waves.Model capabilities are exploited...

  20. Investigation on the wake evolution of contra-rotating propeller using RANS computation and SPIV measurement

    Directory of Open Access Journals (Sweden)

    Kwang-Jun Paik

    2015-05-01

    Full Text Available The wake characteristics of Contra-Rotating Propeller (CRP were investigated using numerical simulation and flow measurement. The numerical simulation was carried out with a commercial CFD code based on a Reynolds Averaged Navier-Stokes (RANS equations solver, and the flow measurement was performed with Stereoscopic Particle Image Velocimetry (SPIV system. The simulation results were validated through the comparison with the experiment results measured around the leading edge of rudder to investigate the effect of propeller operation under the conditions without propeller, with forward propeller alone, and with both forward and aft propellers. The evolution of CRP wake was analyzed through velocity and vorticity contours on three transverse planes and one longitudinal plane based on CFD results. The trajectories of propeller tip vortex core in the cases with and without aft propeller were also compared, and larger wake contraction with CRP was confirmed.

  1. RANS simulation of cavitation and hull pressure fluctuation for marine propeller operating behind-hull condition

    Directory of Open Access Journals (Sweden)

    Kwang-Jun Paik

    2013-12-01

    Full Text Available Simulations of cavitation flow and hull pressure fluctuation for a marine propeller operating behind a hull using the unsteady Reynolds-Averaged Navier-Stokes equations (RANS are presented. A full hull body submerged under the free surface is modeled in the computational domain to simulate directly the wake field of the ship at the propeller plane. Simulations are performed in design and ballast draught conditions to study the effect of cavitation number. And two propellers with slightly different geometry are simulated to validate the detectability of the numerical simulation. All simulations are performed using a commercial CFD software FLUENT. Cavitation patterns of the simulations show good agreement with the experimental results carried out in Samsung CAvitation Tunnel (SCAT. The simulation results for the hull pressure fluctuation induced by a propeller are also compared with the experimental results showing good agreement in the tendency and amplitude, especially, for the first blade frequency.

  2. A RANS modelling approach for predicting powering performance of ships in waves

    Directory of Open Access Journals (Sweden)

    Björn Windén

    2014-06-01

    Full Text Available In this paper, a modelling technique for simulating self-propelled ships in waves is presented. The flow is modelled using a RANS solver coupled with an actuator disk model for the propeller. The motion of the ship is taken into consideration in the definition of the actuator disk region as well as the advance ratio of the propeller. The RPM of the propeller is controlled using a PID-controller with constraints added on the maximum permissible RPM increase rate. Results are presented for a freely surging model in regular waves with different constraints put on the PID-controller. The described method shows promising results and allows for the studying of several factors relating to self-propulsion. However, more validation data is needed to judge the accuracy of the model.

  3. Optimizing small cell deployment by the use of C-RANs

    DEFF Research Database (Denmark)

    Checko, Aleksandra; Holm, Henrik Laumand; Christiansen, Henrik Lehrmann

    2014-01-01

    conditions. Furthermore, based on theoretical calculations and Network simulations we present considerations on deployment scenarios to optimize green field deployments in terms of Total Cost of Ownership (TCO). This involves optimizing the mix of cells with different traffic profiles and the BBU Pool......A Cloud Radio Access Network (C-RAN) is a novel mobile network architecture that has the potential to support extremely dense mobile network deployments enhancing the network capacity while offering cost savings on baseband resources. In this work we analyze cell traffic profiles and evaluate...... the conditions that impact the statistical multiplexing gain in the Baseband Unit (BBU) Pool. We conclude on the set of parameters that maximize the statistical multiplexing gain, leading to the highest potential cost savings. We then propose a packet based architecture that can adapt to changing traffic...

  4. Galaxy evolution. Isolated compact elliptical galaxies: stellar systems that ran away.

    Science.gov (United States)

    Chilingarian, Igor; Zolotukhin, Ivan

    2015-04-24

    Compact elliptical galaxies form a rare class of stellar system (~30 presently known) characterized by high stellar densities and small sizes and often harboring metal-rich stars. They were thought to form through tidal stripping of massive progenitors, until two isolated objects were discovered where massive galaxies performing the stripping could not be identified. By mining astronomical survey data, we have now found 195 compact elliptical galaxies in all types of environment. They all share similar dynamical and stellar population properties. Dynamical analysis for nonisolated galaxies demonstrates the feasibility of their ejection from host clusters and groups by three-body encounters, which is in agreement with numerical simulations. Hence, isolated compact elliptical and isolated quiescent dwarf galaxies are tidally stripped systems that ran away from their hosts. Copyright © 2015, American Association for the Advancement of Science.

  5. Flow field analysis of a pentagonal-shaped bridge deck by unsteady RANS

    Directory of Open Access Journals (Sweden)

    Md. Naimul Haque

    2016-01-01

    Full Text Available Long-span cable-stayed bridges are susceptible to dynamic wind effects due to their inherent flexibility. The fluid flow around the bridge deck should be well understood for the efficient design of an aerodynamically stable long-span bridge system. In this work, the aerodynamic features of a pentagonal-shaped bridge deck are explored numerically. The analytical results are compared with past experimental work to assess the capability of two-dimensional unsteady RANS simulation for predicting the aerodynamic features of this type of deck. The influence of the bottom plate slope on aerodynamic response and flow features was investigated. By varying the Reynolds number (2 × 104 to 20 × 104 the aerodynamic behavior at high wind speeds is clarified.

  6. A RANS/DES Numerical Procedure for Axisymmetric Flows with and without Strong Rotation

    Energy Technology Data Exchange (ETDEWEB)

    Andrade, Andrew Jacob [Univ. of California, Davis, CA (United States)

    2007-01-01

    A RANS/DES numerical procedure with an extended Lax-Wendroff control-volume scheme and turbulence model is described for the accurate simulation of internal/external axisymmetric flow with and without strong rotation. This new procedure is an extension, from Cartesian to cylindrical coordinates, of (1) a second order accurate multi-grid, control-volume integration scheme, and (2) a k-ω turbulence model. This paper outlines both the axisymmetric corrections to the mentioned numerical schemes and the developments of techniques pertaining to numerical dissipation, multi-block connectivity, parallelization, etc. Furthermore, analytical and experimental case studies are presented to demonstrate accuracy and computational efficiency. Notes are also made toward numerical stability of highly rotational flows.

  7. A Synthesis of Hybrid RANS/LES CFD Results for F-16XL Aircraft Aerodynamics

    Science.gov (United States)

    Luckring, James M.; Park, Michael A.; Hitzel, Stephan M.; Jirasek, Adam; Lofthouse, Andrew J.; Morton, Scott A.; McDaniel, David R.; Rizzi, Arthur M.

    2015-01-01

    A synthesis is presented of recent numerical predictions for the F-16XL aircraft flow fields and aerodynamics. The computational results were all performed with hybrid RANS/LES formulations, with an emphasis on unsteady flows and subsequent aerodynamics, and results from five computational methods are included. The work was focused on one particular low-speed, high angle-of-attack flight test condition, and comparisons against flight-test data are included. This work represents the third coordinated effort using the F-16XL aircraft, and a unique flight-test data set, to advance our knowledge of slender airframe aerodynamics as well as our capability for predicting these aerodynamics with advanced CFD formulations. The prior efforts were identified as Cranked Arrow Wing Aerodynamics Project International, with the acronyms CAWAPI and CAWAPI-2. All information in this paper is in the public domain.

  8. Malaysia; Selected Issues

    OpenAIRE

    International Monetary Fund

    2014-01-01

    This Selected Issues paper on Malaysia highlights quantitative assessment of additional measures required during the medium term to achieve fiscal targets. The authorities aim to lower the budget deficit to about 3 percent of GDP by 2015, down from 4.0 percent in 2013, and to balance the budget by 2020. It suggests that ranking fiscal instruments under different fiscal policy goals can help policymakers identify the composition of fiscal adjustment based on their preferences. By combining ran...

  9. Trabajadoras domésticas nicaraguenses en Costa Rica: un camino tortuoso hacia el reconocimiento

    Directory of Open Access Journals (Sweden)

    Alexandra Bonnie

    2010-12-01

    Full Text Available El trabajo doméstico es un sector históricamente vulnerable: se considera a menudo como precario, mal retribuido, inseguro y desprotegido. Los y las trabajadores/as domésticos/as sufren discriminación, aún más cuando son mujeres y extranjeros.El presente artículo pretende estudiar las condiciones laborales de las trabajadoras domésticas en Costa Rica frente a dos importantes evoluciones jurídicas recientes: la reforma del capítulo VIII del Código de Trabajo, relativo al trabajo doméstico remunerado, en 2009, y la entrada en vigor de la nueva Ley General de Migracióny Extranjería, en 2010, que afecta a las trabajadoras domésticas migrantes. Como en otros países, las trabajadoras domésticas nacionales y migrantes se organizaron para obtener el reconocimiento de sus derechos laborales, lo que se concretó en el año 2009 con la reforma del Código de Trabajo, considerado como discriminatorio.Esto fue un gran paso para el mejoramiento de su condición, y se destaca el rol importante que tuvo la Asociación de Trabajadoras Domésticas (ASTRADOMES.Sin embargo, la modificación de la normativa no se concreta de igual manera para todas las trabajadoras domésticas. Persisten situaciones de vulnerabilidad y abusos, sobre todo en el caso de las trabajadoras migrantes nicaragüenses. Ello conduce a plantear la necesidad de implementar una política pública integral que atiende a las necesidades de las personas cualquiera sea su nacionalidad y estatus migratorio.El estudio está basado en el análisis de fuentes secundarias tanto académicas como jurídicas. Se complementó la información con entrevistas semiestructuradas a informantes clave, incluyendo a representantes de trabajadoras domésticas.

  10. RANS based CFD methodology for a real scale 217-pin wire-wrapped fuel assembly of KAERI PGSFR

    Energy Technology Data Exchange (ETDEWEB)

    Jeong, Jae-Ho, E-mail: jhjeong@kaeri.re.kr [Korea Atomic Energy Research Institute, 989-111 Daedeok-daero, Yuseoung-gu, Daejeon (Korea, Republic of); Song, Min-Seop [Department of Nuclear Engineering, Seoul National University, 559 Gwanak-ro, Gwanak-gu, Seoul (Korea, Republic of); Lee, Kwi-Lim [Korea Atomic Energy Research Institute, 989-111 Daedeok-daero, Yuseoung-gu, Daejeon (Korea, Republic of)

    2017-03-15

    Highlights: • This paper presents a suitable way for a practical RANS based CFD methodology which is applicable to real scale 217-pin wire-wrapped fuel assembly of KAERI PGSFR. • A key point of differentiation of the RANS based CFD methodology in this study is adapting an innovative grid generation method using a fortran based in-house code with a GGI function in a general-purpose commercial CFD code, CFX. • The RANS based CFD methodology is implemented with high resolution scheme and SST turbulence model in the 7-pin 37-pin, and 127-pin wire-wrapped fuel assembly of PNC and JNC. Furthermore, the RANS based CFD methodology can be successfully extended to the real scale 217-pin wire-wrapped fuel bundles of KAERI PGSFR. • Three-dimensional thermal-hydraulic characteristics have been also investigated briefly. - Abstract: This paper presents a suitable way for a practical RANS (Reynolds Averaged Navier-Stokes simulation) based CFD (Computational Fluid Dynamics) methodology which is applicable to real scale 217-pin wire-wrapped fuel assembly of KAERI (Korea Atomic Energy Research Institute) PGSFR (Prototype Gen-IV Sodium-cooled Fast Reactor). The main purpose of the current study is to support license issue for the KAERI PGSFR core safety and to elucidate thermal-hydraulic characteristics in a 217-pin wire-wrapped fuel assembly of KAERI PGSFR. A key point of differentiation of the RANS based CFD methodology in this study is adapting an innovative grid generation method using a fortran based in-house code with a GGI (General Grid Interface) function in a general-purpose commercial CFD code, CFX. The innovative grid generation method with GGI function can achieve to simulate a real wire shape with minimizing cell skewness. The RANS based CFD methodology is implemented with high resolution scheme in convection term and SST (Shear Stress Transport) turbulence model in the 7-pin 37-pin, and 127-pin wire-wrapped fuel assembly of PNC (Power reactor and Nuclear fuel

  11. Central projection of pain arising from delayed onset muscle soreness (DOMS in human subjects.

    Directory of Open Access Journals (Sweden)

    Katharina Zimmermann

    Full Text Available Delayed onset muscle soreness (DOMS is a subacute pain state arising 24-48 hours after a bout of unaccustomed eccentric muscle contractions. Functional magnetic resonance imaging (fMRI was used to examine the patterns of cortical activation arising during DOMS-related pain in the quadriceps muscle of healthy volunteers evoked by either voluntary contraction or physical stimulation. The painful movement or physical stimulation of the DOMS-affected thigh disclosed widespread activation in the primary somatosensory and motor (S1, M1 cortices, stretching far beyond the corresponding areas somatotopically related to contraction or physical stimulation of the thigh; activation also included a large area within the cingulate cortex encompassing posteroanterior regions and the cingulate motor area. Pain-related activations were also found in premotor (M2 areas, bilateral in the insular cortex and the thalamic nuclei. In contrast, movement of a DOMS-affected limb led also to activation in the ipsilateral anterior cerebellum, while DOMS-related pain evoked by physical stimulation devoid of limb movement did not.

  12. Optical properties of dissolved organic matter (DOM): Effects of biological and photolytic degradation

    Science.gov (United States)

    Hansen, Angela; Kraus, Tamara; Pellerin, Brian; Fleck, Jacob; Downing, Bryan D.; Bergamaschi, Brian

    2016-01-01

    Advances in spectroscopic techniques have led to an increase in the use of optical properties (absorbance and fluorescence) to assess dissolved organic matter (DOM) composition and infer sources and processing. However, little information is available to assess the impact of biological and photolytic processing on the optical properties of original DOM source materials. We measured changes in commonly used optical properties and indices in DOM leached from peat soil, plants, and algae following biological and photochemical degradation to determine whether they provide unique signatures that can be linked to original DOM source. Changes in individual optical parameters varied by source material and process, with biodegradation and photodegradation often causing values to shift in opposite directions. Although values for different source materials overlapped at the end of the 111-day lab experiment, multivariate statistical analyses showed that unique optical signatures could be linked to original DOM source material even after degradation, with 17 optical properties determined by discriminant analysis to be significant (poptical properties is possible when parameters are evaluated in combination even after extensive biological and photochemical alteration.

  13. Sobre a Humilhação no Cotidiano do Emprego Doméstico

    Directory of Open Access Journals (Sweden)

    Jefferson Belarmino de Freitas

    2014-03-01

    Full Text Available En este artículo, trato las situaciones de humillación como eventos intrínsecos al cotidiano del empleo doméstico en la Región Metropolitana de São Paulo (RMSP. Me centro, particularmente, en las interacciones cotidianas entre empleadoras y empleadas domésticas en lo que puede clasificarse como empleo doméstico en el que se hace todo (es decir, donde no se delimitan las tareas que ejecutarán las trabajadoras. Argumento que las situaciones de humillación que esta ocupación engendra están vinculadas, sobre todo, a la distancia social, que actúa sobre el encuentro entre contratantes y contratadas. En pocas palabras, prepondera, en el cotidiano del empleo doméstico, la humillación de la distancia social. Este artículo se basa, en primer lugar, en diez entrevistas realizadas con empleadas domésticas que viven en la RMSP; pero también se apoya en el análisis de textos periodísticos que tratan situaciones de conflicto vividas en el día a día de las personas que desempeñan esa ocupación.

  14. The Emperor Dom Pedro II: his convulsive seizures when a boy O imperador Dom Pedro II: as suas crises convulsivas quando menino

    Directory of Open Access Journals (Sweden)

    Marleide da Mota Gomes

    2007-12-01

    Full Text Available INTRODUCTION: Dom Pedro II, the Prince Heir and Emperor under regency, in a delicate period of the construction of the Brazilian nation, had convulsive seizures. OBJECTIVE: To investigate the convulsive seizures and related syndromes of Dom Pedro II and his family, besides the physicians in charge of the health care. METHOD: Narrative review based on primary and secondary sources. CONCLUSION: The scattered and self-limited convulsive seizures associated with physical and mental integrity favored a benign prognosis. Dom Pedro and his family presented rich history of epileptic seizures and febrile convulsion. This variety resembles the diagnosis of generalized epilepsy with febrile seizures plus that seems to be a combination of several syndromes with shared genetic susceptibility.INTRODUÇÃO: Dom Pedro, o príncipe herdeiro e imperador sob regência, em período delicado da formação da nação brasileira, apresentou crises convulsivas que geraram preocupação para o país. OBJETIVO: Investigar a história da epilepsia de Dom Pedro II e da sua família e procurar identificar quais tipos de crises epilépticas estavam presentes, além dos médicos envolvidos com os cuidados de saúde. MÉTODO: Revisão narrativa baseada em fontes primárias e secundárias. CONCLUSÃO: As crises convulsivas esparsas e auto-limitadas associadas a higidez física e mental de Dom Pedro II sugerem um prognóstico benigno. A história de epilepsia idiopática e convulsões febris no imperador e em outros membros da sua família aponta para o diagnóstico mais provável de Epilepsia Generalizada com Convulsões Febris Plus que é determinada por uma combinação de alguns tipos de manifestações epilépticas com suscetibilidade genética compartilhada.

  15. RANS / LES coupling applied to high Reynolds number turbulent flows of the nuclear industry; Application du couplage RANS / LES aux ecoulements turbulents a haut nombre de Reynolds de l'industrie nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Benarafa, Y

    2005-12-15

    The main issue to perform a computational study of high Reynolds numbered turbulent flows consists on predicting their unsteadiness without implying a tremendous computational cost. First, the main drawbacks of large-eddy simulation with standard wall model on a coarse mesh for a plane channel flow are highlighted. To correct these drawbacks two coupling RANS/LES methods have been proposed. The first one relies on a sophisticated wall model (TBLE) which consists on solving Thin Boundary Layer Equations with a RANS type turbulent closure in the near wall region. The second one consists on a RANS/LES methods have been proposed. The second one consists on a RANS/LES coupling method using a forcing term approach. These various approaches have been implemented in the TRIO-U code developed at CEA (French Atomic Center) at Grenoble, France. The studied flow configurations are the fully developed plane channel flow and a flow around a surface-mounted cubical obstacle. Both approaches provide encouraging results and allow a surface-mounted cubical obstacle. Both approaches provide encouraging results and allow unsteady simulations for a low computational cost. (author)

  16. Effects of tender point acupuncture on delayed onset muscle soreness (DOMS – a pragmatic trial

    Directory of Open Access Journals (Sweden)

    Kitakoji Hiroshi

    2008-11-01

    Full Text Available Abstract Background Acupuncture is used to reduce inflammation and decrease pain in delayed onset muscle soreness (DOMS. This study investigates the efficacy of acupuncture on the symptoms of DOMS. Methods Thirty subjects were assigned randomly to there groups, namely the control, non-tender point and tender point groups. Measurement of pain with full elbow flexion was used as indices of efficacy. Measurements were taken before and after exercise, immediately after treatment and seven days after treatment. Results Significant differences in visual analog scores for pain were found between the control group and tender point group immediately after treatment and three days after exercise (P Conclusion The results show that tender point acupuncture relieves muscle pain of DOMS.

  17. Pain-evoked trunk muscle activity changes during fatigue and DOMS

    DEFF Research Database (Denmark)

    Larsen, Lars Henrik; Hirata, Rogerio Pessoto; Graven-Nielsen, Thomas

    2017-01-01

    BACKGROUND:Muscle pain may reorganize trunk muscle activity but interactions with exercise-related muscle fatigue and delayed onset muscle soreness (DOMS) is to be clarified.METHODS:In 19 healthy participants, the trunk muscle activity during 20 multi-directional unpredictable surface perturbations...... were recorded after bilateral isotonic saline injections (control) and during unilateral and bilateral hypertonic saline-induced low back pain (LBP) in conditions of back muscle fatigue (Day-1) and DOMS (Day-2). Pain intensity and distribution were assessed by visual analogue scale (VAS) scores...... and pain drawings. The degree of fatigue and DOMS were assessed by Likert scale scores. Root-mean-square electromyographic (RMS-EMG) signals were recorded post-perturbation from six bilateral trunk muscles and the difference from baseline conditions (Delta-RMS-EMG) was extracted and averaged across...

  18. Domácí násilí z pohledu týraných žen a z pohledu personálu o ně pečujícího

    OpenAIRE

    Michalčíková, Lucie

    2010-01-01

    - 66 - ANNOTATION Author: Lucie Michalčíková Institution: Department of Social Medicine LF UK in Hradec Králové Nursing Department Title: Domestic violence from point of womens and nurses Leading tutor: PhDr. Mariana Bažantová Page count: 78 stran Attachments: 6 p íloh Year of defence: 2010 Keywords Violence, family, forms of violence, violence in family, pathological behaviour, partnership, intervention, syndrome of learned powerlessness, learned powerlessness, society, law. Anotation Bachel...

  19. Ny dom gør CFC-lovgivningen overflødig

    DEFF Research Database (Denmark)

    Winther-Sørensen, Niels

    1995-01-01

    I artiklen fokuseres på kriteriet 'ledelsens sæde'. Det anføres, at en nyligt afsagt dom, TfS 1995, 577 VLD medfører, at en lang række udenlandske datterselskaber underkastes fuld skattepligt til Danmark. Dommen, der anket til Højesteret, kritiseres.......I artiklen fokuseres på kriteriet 'ledelsens sæde'. Det anføres, at en nyligt afsagt dom, TfS 1995, 577 VLD medfører, at en lang række udenlandske datterselskaber underkastes fuld skattepligt til Danmark. Dommen, der anket til Højesteret, kritiseres....

  20. Første dom om insiderhandel - rækkevidde og konsekvenser

    DEFF Research Database (Denmark)

    Clausen, Nis Jul

    1995-01-01

    I artiklen behandles nogle af de principielle spørgsmål, som den første dom om insiderhandel - UfR 1995. 905H - berører. Der stilles en række forslag til nye regler vedr. ledelsens og medarbejderes handel med værdipapirer.......I artiklen behandles nogle af de principielle spørgsmål, som den første dom om insiderhandel - UfR 1995. 905H - berører. Der stilles en række forslag til nye regler vedr. ledelsens og medarbejderes handel med værdipapirer....

  1. Abordaje de la violencia doméstica (VD) en los servicios de urgencias (SUH)

    OpenAIRE

    Sánchez Ramón, Susana

    2007-01-01

    Los servicios de urgencias son a veces los lugares más accesibles que encuentran las mujeres víctimas de malos tratos para solicitar ayuda y así, se detectan cifras altas de violencia doméstica (VD) entre las usuarias de estos centros. Según las cifras publicadas en diferentes trabajos realizados en los Servicios de Urgencias Hospitalarias (SUH) de los Estados Unidos, de un 11.7% - 35% de las mujeres que acuden a dichos servicios lo hacen como consecuencia de la violencia doméstica, Estos est...

  2. Grupos domésticos pobres, diabetes y género: renovarse o morir

    OpenAIRE

    Laura Elena Trujillo Olivera; Austreberta Nazar Beutelspacher; Emma Zapata Martelo; Erin I.J. Estrada Lugo

    2008-01-01

    Con base en las categorías de análisis de género se propone una tipología de grupo doméstico. Se aplicó metodología cualitativa para explorar las formas en que las relaciones de género conforman interacciones generadoras de oportunidades desiguales para el autocuidado de diabetes mellitus entre mujeres y hombres. Se entrevistó en profundidad a 23 mujeres y hombres que padecen diabetes para acercarse a comprender la forma en que unas y otros, durante la cotidiana interacción doméstica...

  3. Morfologia das domácias foliares de Miconia sellowiana Naudin (Melastomataceae

    Directory of Open Access Journals (Sweden)

    Letícia Larcher

    2011-10-01

    Full Text Available http://dx.doi.org/10.5007/2175-7925.2012v25n1p1 Domácias são cavidades encontradas na superfície foliar que proporcionam condições físicas para a existência de artrópodes, caracterizando uma relação mutualística. Apesar da importância ecológica das domácias, poucos estudos descrevem sua estrutura e relação com o ambiente. Miconia sellowiana apresenta domácias na face abaxial da folha e estudos prévios sobre essa espécie, oriundas de duas fitofisionomias, indicaram a influência  dos fatores ambientais sobre a morfologia foliar. Assim, esse estudo analisou comparativamente a morfologia das domácias foliares de M. sellowiana e a influência dos fatores ambientais nestas estruturas. Folhas provenientes da Estepe-gramíneo-lenhosa e da Floresta Ombrófila Mista foram coletadas para a análise da espessura e a área das domácias, assim como a área, a massa seca e a espessura do limbo. As folhas de M. sellowiana apresentaram apenas um tipo de domácia, na face abaxial e basal da folha, com uma estrutura anatômica mais simples do que a lâmina foliar na qual estão localizadas, com ausência de estômatos e de mesofilo dorsiventral, sugerindo que a capacidade fotossintética das domácias é menor que a da lâmina foliar. A variação morfológica nas domácias entre as duas áreas/regiões ocorreu apenas no tamanho, representado pela maior área nas folhas da Estepe Gramíneo Lenhosa, indicando a influência dos fatores ambientais na seleção dos ácaros hospedeiros.

  4. A dor de um doce lar: narrativas da violência doméstica

    OpenAIRE

    Socorro Alves da Silva

    2009-01-01

    O estudo da violência doméstica é um tema de suma importância que vem despertando interesse por parte de pesquisadores das ciências humanas e sociais. Com o intuito de contribuir para o aprofundamento desta temática, esta pesquisa teve como objetivo compreender a experiência de mulheres em situação de violência doméstica e os modos como estas mulheres subjetivam esta violência. Trata-se de um trabalho que pretendeu colocar em pauta a necessidade de uma organização de serviços voltados a esta ...

  5. Pluriatividade, pobreza rural e serviço doméstico remunerado

    OpenAIRE

    Nascimento, Carlos Alves do

    2004-01-01

    Este trabalho se propôs analisar, com base nos microdados da Pesquisa Nacional por Amostra de Domicílios (PNAD) - anos 1992-1999 e 2001 -, a participação da renda do serviço doméstico remunerado entre determinados tipos de famílias rurais pobres que apresentaram taxas de crescimento negativas nos anos 90, demonstrando que, em diversos casos, a renda do serviço doméstico explica melhor a redução da pobreza rural do que as transferências governamentais (aposentadorias e pensões). Para tanto, re...

  6. 78 FR 34084 - Freeport-McMoRan Energy LLC; Application for Long-Term Authorization To Export Liquefied Natural...

    Science.gov (United States)

    2013-06-06

    ... Freeport-McMoRan Energy LLC; Application for Long-Term Authorization To Export Liquefied Natural Gas... natural gas (non-FTA countries) with which trade is not prohibited by U.S. law or policy. FME requests... Natural Gas Act (NGA), 15 U.S.C. 717b(c).\\3\\ In the current Application, FME requests both FTA and non...

  7. A comparison of RANS computations and wind tunnel tests for RMS pressures on a high-rise building model

    NARCIS (Netherlands)

    Kalkman, I.M.; Bronkhorst, A.J.; Bentum, C.A. van; Franke, J.

    2012-01-01

    Five root-mean-square (RMS) pressure models are used in combination with different turbulence models to determine whether it is possible to obtain a conservative estimate of RMS pressures on a high-rise building model from a RANS calculation. When a precursor domain is used for the generation of

  8. RANS-VOF modeling of hydrodynamics and sand transport under full-scale non-breaking and breaking waves

    NARCIS (Netherlands)

    Fernandez Mora, Maria de Los Angeles; Ribberink, Jan S.; van der Zanden, Joep; van der Werf, Jebbe J.; Jacobsen, N.G.; Lynett, P.; Lynett, Patrick

    2017-01-01

    A 2D RANS-VOF model is used to simulate the flow and sand transport for two different full-scale laboratory experiments: i) non-breaking waves over a horizontal sand bed (Schretlen et al., 2011) and ii) plunging breaking waves over a barred mobile bed profile (Van der Zanden et al., 2016). For the

  9. Dom Pedro I of Brazil and IV of Portugal epilepsy and peculiar behavior Epilepsia e comportamento peculiar de Dom Pedro I do Brasil e IV de Portugal

    Directory of Open Access Journals (Sweden)

    Marleide da Mota Gomes

    2007-09-01

    Full Text Available We present medical issues related to Dom Pedro de Alcântara Bragança e Bourbon (1798-1834, first Emperor of Brazil. This is made by means of narrative revision on historical facts starting from primary and secondary sources. Dom Pedro presented familiar incidence of epilepsy. His seizures were relatively benign and scattered, supposedly started at the age of 13: idiophatic epilepsy with generalized tonic-clonic seizures only or juvenile myoclonic epilepsy. He also had behavioral disorder characterized by hypersexuality, agitation and impulsiveness. It could have facilitated his opportunistic behavior necessary of daring to transgress the conservatism of the Portuguese crown, to create the constitutional monarchism in Brazil and in Portugal.Apresentamos aspectos médicos relacionadas a Dom Pedro de Alcântara Bragança e Bourbon (1798-1834, primeiro Imperador do Brasil. Isso é feito por meio de revisão narrativa sobre fatos históricos baseados em fontes primárias ou secundárias. Dom Pedro apresentou epilepsia de incidência familiar. Suas crises eram relativamente benignas e esparsas, de início provavelmente aos 13 anos: epilepsia idiopática generalizada com crises tônico-clônicas apenas ou epilepsia mioclônica juvenil. Ele também tinha transtorno do comportamento caracterizado por hipersexualidade, agitação e impulsividade. Isso pode ter facilitado seu comportamento oportunístico necessário para ousar a transgredir o conservadorismo da coroa portuguesa e criar o monarquismo constitucional no Brasil e em Portugal.

  10. Dom João VI's death: convulsions and coma Morte de Dom João VI: convulsões e coma

    Directory of Open Access Journals (Sweden)

    Marleide da Mota Gomes

    2007-12-01

    Full Text Available Dom João VI's death occurred in adverse political conditions that led to the regicide hypothesis. The main aim of this paper is to mention life style and conditions of the death of the king by means of narrative review based on primary and secondary sources. Dom João VI died in the way of convulsions and gastrointestinal symptoms. This could be the result of the pathological chain of genetic determination, accentuated by the inappropriate life style, obesity and sedentary habits, and/or poisoning. The finding of arsenic in high doses in his viscera favors the last hypothesis as the basic cause of death, but one can not discard the atherosclerosis predisposing risk factors for a final stroke.A morte de Dom João VI aconteceu em condições políticas adversas que conduziram à hipótese de regicídio. O objetivo principal deste artigo é mencionar o estilo de vida e condições da morte do rei por meio de revisão narrativa baseada em fontes primárias e secundárias. Dom João VI morreu apresentando convulsões e sintomas gastrointestinais. Esse poderia ser o resultado da cadeia patológica de determinação genética, acentuada pelo estilo de vida inapropriado, obesidade e/ou envenenamento. O achado de arsênico em doses altas nas suas vísceras aponta a última hipótese como a causa básica da morte, mas não se pode descartar a aterosclerose como fator de risco predisponente para um acidente vascular cerebral final.

  11. Repeat Associated Non-AUG Translation (RAN Translation Dependent on Sequence Downstream of the ATXN2 CAG Repeat.

    Directory of Open Access Journals (Sweden)

    Daniel R Scoles

    Full Text Available Spinocerebellar ataxia type 2 (SCA2 is a progressive autosomal dominant disorder caused by the expansion of a CAG tract in the ATXN2 gene. The SCA2 disease phenotype is characterized by cerebellar atrophy, gait ataxia, and slow saccades. ATXN2 mutation causes gains of toxic and normal functions of the ATXN2 gene product, ataxin-2, and abnormally slow Purkinje cell firing frequency. Previously we investigated features of ATXN2 controlling expression and noted expression differences for ATXN2 constructs with varying CAG lengths, suggestive of repeat associated non-AUG translation (RAN translation. To determine whether RAN translation occurs for ATXN2 we assembled various ATXN2 constructs with ATXN2 tagged by luciferase, HA or FLAG tags, driven by the CMV promoter or the ATXN2 promoter. Luciferase expression from ATXN2-luciferase constructs lacking the ATXN2 start codon was weak vs AUG translation, regardless of promoter type, and did not increase with longer CAG repeat lengths. RAN translation was detected on western blots by the anti-polyglutamine antibody 1C2 for constructs driven by the CMV promoter but not the ATXN2 promoter, and was weaker than AUG translation. Strong RAN translation was also observed when driving the ATXN2 sequence with the CMV promoter with ATXN2 sequence downstream of the CAG repeat truncated to 18 bp in the polyglutamine frame but not in the polyserine or polyalanine frames. Our data demonstrate that ATXN2 RAN translation is weak compared to AUG translation and is dependent on ATXN2 sequences flanking the CAG repeat.

  12. Histological Analysis Of Selected Muscles In Ostrich ( Struthio camelus var.dom.

    Directory of Open Access Journals (Sweden)

    Svätoslav Hluchý

    2013-10-01

    Full Text Available We found that the percentage of individual muscle components show statistically significant differences in all analyzed muscles. More α-red fibers were found in m. iliotibialis lateralis and m. femorotibialis externus, while abundance of white (α-white muscle fibers was very low. Unlike other species of birds (turkey, chicken, geese in all studied muscles, proportion of all red fibers (a-red and b-red greatly exceeded the proportion of white muscle fibers (a-white . Adipose tissue content in individual muscles ranged from 0.0% (m. iliotibialis lateralis to 1.67% (m gastrocnemius.

  13. Produtividade da mamona irrigada com esgoto doméstico tratado Productivity of castor bean irrigated with treated domestic sewage

    Directory of Open Access Journals (Sweden)

    Neyliane C. de Souza

    2010-05-01

    Full Text Available A mamoneira (Ricinus communis L., oleaginosa de relevante importância econômica e social no Nordeste, apresenta-se como alternativa para a produção do biodiesel. O experimento objetivou avaliar, em escala real, os aspectos produtivos da cultura da mamona irrigada com esgoto doméstico tratado. Empregou-se o sistema de microaspersão; a delimitação experimental foi de quatro repetições e quatro tratamentos: T1: água do poço e adubação recomendada; T2: esgoto doméstico tratado e adubação recomendada; T3: somente esgoto doméstico tratado e T4: esgoto doméstico tratado e metade da adubação recomendada. Verificou-se que as unidades irrigadas com esgoto tratado superaram as irrigadas com água, em quase todas as variáveis analisadas. A produtividade foi maior nos tratamentos irrigados com esgoto e adubação (T2 e (T4, alcançando produtividade de 1.986 e 1.412 kg ha-1, respectivamente. O teor de óleo contido nas sementes foi analisado e não apresentou nenhuma diferença significativa entre os tratamentos com adubação (T1, T2 e T4, sendo que o tratamento com esgoto tratado (T3 forneceu baixíssimos teores de óleo na semente.The castor bean (Ricinus communis L., an oil crop of economic and social importance for the Northeast region of Brazil, can be used for biodiesel production. The experiment aimed to evaluate, at a realistic scale, the productive aspects of the castor bean irrigated with treated sewage. Microsprinkler irrigation method was selected, and the experimental set-up consisted of four repetitions and four different treatments: well water and recommended fertilization (T1; treated wastewater and recommended fertilization (T2; treated wastewater without external recommended fertilization (T3; and treated wastewater and half of recommended fertilization (T4. It was found that units irrigated with treated sewage exceeded the ones irrigated with well water in almost all variables. The highest productivities were in the

  14. RANS Modeling of Stably Stratified Turbulent Boundary Layer Flows in OpenFOAM®

    Directory of Open Access Journals (Sweden)

    Wilson Jordan M.

    2015-01-01

    Full Text Available Quantifying mixing processes relating to the transport of heat, momentum, and scalar quantities of stably stratified turbulent geophysical flows remains a substantial task. In a stably stratified flow, such as the stable atmospheric boundary layer (SABL, buoyancy forces have a significant impact on the flow characteristics. This study investigates constant and stability-dependent turbulent Prandtl number (Prt formulations linking the turbulent viscosity (νt and diffusivity (κt for modeling applications of boundary layer flows. Numerical simulations of plane Couette flow and pressure-driven channel flow are performed using the Reynolds-averaged Navier-Stokes (RANS framework with the standard k-ε turbulence model. Results are compared with DNS data to evaluate model efficacy for predicting mean velocity and density fields. In channel flow simulations, a Prandtl number formulation for wall-bounded flows is introduced to alleviate overmixing of the mean density field. This research reveals that appropriate specification of Prt can improve predictions of stably stratified turbulent boundary layer flows.

  15. Validation of the simpleFoam (RANS solver for the atmospheric boundary layer in complex terrain

    Directory of Open Access Journals (Sweden)

    Peralta C.

    2014-01-01

    Full Text Available We validate the simpleFoam (RANS solver in OpenFOAM (version 2.1.1 for simulating neutral atmospheric boundary layer flows in complex terrain. Initial and boundary conditions are given using Richards and Hoxey proposal [1]. In order to obtain stable simulation of the ABL, modified wall functions are used to set the near-wall boundary conditions, following Blocken et al remedial measures [2]. A structured grid is generated with the new library terrainBlockMesher [3,4], based on OpenFOAM's blockMesh native mesher. The new tool is capable of adding orographic features and the forest canopy. Additionally, the mesh can be refined in regions with complex orography. We study both the classical benchmark case of Askervein hill [5] and the more recent Bolund island data set [6]. Our purpose is two-folded: to validate the performance of OpenFOAM steady state solvers, and the suitability of the new meshing tool to generate high quality structured meshes, which will be used in the future for performing more computationally intensive LES simulations in complex terrain.

  16. A Game-Theoretical Approach for Spectrum Efficiency Improvement in Cloud-RAN

    Directory of Open Access Journals (Sweden)

    Zhuofu Zhou

    2016-01-01

    Full Text Available As tremendous mobile devices access to the Internet in the future, the cells which can provide high data rate and more capacity are expected to be deployed. Specifically, in the next generation of mobile communication 5G, cloud computing is supposed to be applied to radio access network. In cloud radio access network (Cloud-RAN, the traditional base station is divided into two parts, that is, remote radio heads (RRHs and base band units (BBUs. RRHs are geographically distributed and densely deployed, so as to achieve high data rate and low latency. However, the ultradense deployment inevitably deteriorates spectrum efficiency due to the severer intercell interference among RRHs. In this paper, the downlink spectrum efficiency can be improved through the cooperative transmission based on forming the coalitions of RRHs. We formulate the problem as a coalition formation game in partition form. In the process of coalition formation, each RRH can join or leave one coalition to maximize its own individual utility while taking into account the coalition utility at the same time. Moreover, the convergence and stability of the resulting coalition structure are studied. The numeric simulation result demonstrates that the proposed approach based on coalition formation game is superior to the noncooperative method in terms of the aggregate coalition utility.

  17. RANS SIMULATION OF HYDROFOIL EFFECTS ON HYDRODYNAMIC COEFFICIENTS OF A PLANING CATAMARAN

    Directory of Open Access Journals (Sweden)

    Amin Najafi

    2016-03-01

    Full Text Available Determination of high-speed crafts’ hydrodynamic coefficients will help to analyze the dynamics of these kinds of vessels and the factors affecting their dynamic stabilities. Also, it can be useful and effective in controlling the vessel instabilities. The main purpose of this study is to determine the coefficients of longitudinal motions of a planing catamaran with and without a hydrofoil using RANS method to evaluate the foil effects on them. Determination of hydrodynamic coefficients by experimental approach is costly, and requires meticulous laboratory equipment; therefore, utilizing numerical methods and developing a virtual laboratory seems highly efficient. In the present study, the numerical results for hydrodynamic coefficients of a high-speed craft are verified against Troesch’s (1992 experimental results. In the following, after determination of hydrodynamic coefficients of a planing catamaran with and without foil, the foil effects on its hydrodynamic coefficients are evaluated. The results indicate that most of the coefficients are frequency independent especially at high frequencies.

  18. Aurora A phosphorylates MCAK to control ran-dependent spindle bipolarity.

    Science.gov (United States)

    Zhang, Xin; Ems-McClung, Stephanie C; Walczak, Claire E

    2008-07-01

    During mitosis, mitotic centromere-associated kinesin (MCAK) localizes to chromatin/kinetochores, a cytoplasmic pool, and spindle poles. Its localization and activity in the chromatin region are regulated by Aurora B kinase; however, how the cytoplasmic- and pole-localized MCAK are regulated is currently not clear. In this study, we used Xenopus egg extracts to form spindles in the absence of chromatin and centrosomes and found that MCAK localization and activity are tightly regulated by Aurora A. This regulation is important to focus microtubules at aster centers and to facilitate the transition from asters to bipolar spindles. In particular, we found that MCAK colocalized with NuMA and XMAP215 at the center of Ran asters where its activity is regulated by Aurora A-dependent phosphorylation of S196, which contributes to proper pole focusing. In addition, we found that MCAK localization at spindle poles was regulated through another Aurora A phosphorylation site (S719), which positively enhances bipolar spindle formation. This is the first study that clearly defines a role for MCAK at the spindle poles as well as identifies another key Aurora A substrate that contributes to spindle bipolarity.

  19. Simulating wind and marine hydrokinetic turbines with actuator lines in RANS and LES

    Science.gov (United States)

    Bachant, Peter; Wosnik, Martin

    2015-11-01

    As wind and marine hydrokinetic (MHK) turbine designs mature, focus is shifting towards improving turbine array layouts for maximizing overall power output, i.e., minimizing wake interference for axial-flow or horizontal-axis turbines, or taking advantage of constructive wake interaction for cross-flow or vertical-axis turbines. Towards this goal, an actuator line model (ALM) was developed to provide a computationally feasible method for simulating full turbine arrays inside Navier-Stokes models. The ALM predicts turbine loading with the blade element method combined with sub-models for dynamic stall and flow curvature. The open-source software is written as an extension library for the OpenFOAM CFD package, which allows the ALM body force to be applied to their standard RANS and LES solvers. Turbine forcing is also applied to volume of fluid (VOF) models, e.g., for predicting free surface effects on submerged MHK devices. An additional sub-model is considered for injecting turbulence model scalar quantities based on actuator line element loading. Results are presented for the simulation of performance and wake dynamics of axial- and cross-flow turbines and compared with moderate Reynolds number experiments and body-fitted mesh, blade-resolving CFD. Work supported by NSF-CBET grant 1150797.

  20. Simulation of an Isolated Tiltrotor in Hover with an Unstructured Overset-Grid RANS Solver

    Science.gov (United States)

    Lee-Rausch, Elizabeth M.; Biedron, Robert T.

    2009-01-01

    An unstructured overset-grid Reynolds Averaged Navier-Stokes (RANS) solver, FUN3D, is used to simulate an isolated tiltrotor in hover. An overview of the computational method is presented as well as the details of the overset-grid systems. Steady-state computations within a noninertial reference frame define the performance trends of the rotor across a range of the experimental collective settings. Results are presented to show the effects of off-body grid refinement and blade grid refinement. The computed performance and blade loading trends show good agreement with experimental results and previously published structured overset-grid computations. Off-body flow features indicate a significant improvement in the resolution of the first perpendicular blade vortex interaction with background grid refinement across the collective range. Considering experimental data uncertainty and effects of transition, the prediction of figure of merit on the baseline and refined grid is reasonable at the higher collective range- within 3 percent of the measured values. At the lower collective settings, the computed figure of merit is approximately 6 percent lower than the experimental data. A comparison of steady and unsteady results show that with temporal refinement, the dynamic results closely match the steady-state noninertial results which gives confidence in the accuracy of the dynamic overset-grid approach.

  1. Ras-Related Nuclear Protein Ran3B Gene Is Involved in Hormone Responses in the Embryogenic Callus of Dimocarpus longan Lour.

    Directory of Open Access Journals (Sweden)

    Qilin Tian

    2016-06-01

    Full Text Available Ras-related guanosine triphosphate (GTP-binding nuclear protein (Ran GTPases function as molecular switches and regulate diverse cellular events in eukaryotes. Our previous work suggested that DlRan3B is active during longan (Dimocarpus longan Lour. somatic embryogenesis (SE processes. Herein, subcellular localization of DlRan3B was found to be localized in the nucleus and expression profiling of DlRan3B was performed during longan SE and after exposure to plant hormones (indoleacetic acid (IAA, gibberellin A3 (GA3, salicylic acid (SA, methyl jasmonte (MeJA, and abscisic acid (ABA. We cloned and sequenced 1569 bp of 5′-flanking sequence of DlRan3B (GenBank: JQ279697. Bioinformatic analysis indicated that the promoter contained plant hormone-related regulatory elements. Deletion analysis and responses to hormones identified stimulative and repressive regulatory elements in the DlRan3B promoter. The key elements included those responding to auxin, gibberellin, SA, MeJA, and ABA. DlRan3B was located in the nucleus and accumulated in the late stage of longan SE. The expression of DlRan3B was significantly induced by IAA, GA3, and ABA, but suppressed by SA and MeJA. Promoter transcription was induced by IAA and GA3, but suppressed by SA. Thus, DlRan3B might participate in auxin, gibberellin, and ABA responses during longan late SE, and DlRan3B is involved in phytohormone responsiveness.

  2. Interoperabilidad en Sistemas Domóticos Mediante Pasarela Infrarrojos-ZigBee

    Directory of Open Access Journals (Sweden)

    Gonzalo B. Asencio

    2011-10-01

    Full Text Available Resumen: La domótica consiste en la aplicación de técnicas provenientes de la automática industrial al hogar con objeto de ofrecer servicios que aporten, entre otras cosas, confort, seguridad y eficiencia energética a los usuarios. Hasta el momento la penetración de dichas técnicas en los hogares ha sido reducida. Una de las razones fundamentales de esta lenta transposición de técnicas de control al hogar es la dificultad de integración entre los diferentes sistemas presentes en el hogar. En este artículo se presenta un desarrollo encaminado a mejorar la integración de los sistemas domóticos con aquellos dispositivos que sean controlables mediante infrarrojos. En concreto se ha desarrollado una pasarela inalámbrica que permite a una red domótica el envío de tramas de infrarrojos. De esta manera se posibilita un despliegue rápido y económico de los nodos que sean necesarios para integrar dispositivos tales como los sistemas de aire acondicionado en una red domótica. Copyright c 2011 CEA. Publicado por Elsevier España, S.L. Todos los derechos reservados. Palabras clave: Control a través de redes de comunicación, Impacto social de la automática

  3. Body fat distribution in relation to breast cancer in women participating in the DOM-project

    NARCIS (Netherlands)

    den Tonkelaar, I.; Seidell, J C; Collette, H J

    The association between body fat distribution and breast cancer risk was studied in 5923 pre- and 3568 post-menopausal women, participating in a breast cancer screening project (the DOM-project in Utrecht, the Netherlands). Cases were fifty six premenopausal women and thirty eight postmenopausal

  4. PLecDom: a program for identification and analysis of plant lectin domains.

    Science.gov (United States)

    Shridhar, Smriti; Chattopadhyay, Debasis; Yadav, Gitanjali

    2009-07-01

    PLecDom is a program for detection of Plant Lectin Domains in a polypeptide or EST sequence, followed by a classification of the identified domains into known families. The web server is a collection of plant lectin domain families represented by alignments and profile Hidden Markov Models. PLecDom was developed after a rigorous analysis of evolutionary relationships between available sequences of lectin domains with known specificities. Users can test their sequences for potential lectin domains, catalog the identified domains into broad substrate classes, estimate the extent of divergence of new domains with existing homologs, extract domain boundaries and examine flanking sequences for further analysis. The high prediction accuracy of PLecDom combined with the ease with which it handles large scale input, enabled us to apply the program to protein and EST data from 48 plant genome-sequencing projects in various stages of completion. Our results represent a significant enrichment of the currently annotated plant lectins, and highlight potential targets for biochemical characterization. The search algorithm requires input in fasta format and is designed to process simultaneous connection requests from multiple users, such that huge sets of input sequences can be scanned in a matter of seconds. PLecDom is available at http://www.nipgr.res.in/plecdom.html.

  5. Analyses of soil cadmium and copper contents on a Domérien soil ...

    African Journals Online (AJOL)

    SAM

    2014-03-19

    Mar 19, 2014 ... extracting time and extracted Cd and Cu contents from the two sites' ... And the soil samples from the Domérien soil series were ... A background correction mode was used for Cd analysis (Park et ..... tents on 5 min (2nd) and 10 min (3rd), 20 min (4th) and .... Environment and Plant Ecology (2nd edition).

  6. Machado de Assis's "Dom Casmurro" and "Soneto De Natal": The Calculated Mediocrity of a Mute Prophet

    Science.gov (United States)

    Lewis, Christopher T.

    2016-01-01

    Joaquim Maria Machado de Assis's poem "Soneto de Natal" and the chapter "Um soneto" from his novel "Dom Casmurro" exhibit striking points of intersection that describe the same process: the creation of a sonnet. In the novel, Bentinho abandons his attempt with only a first and last line. "Soneto de Natal"…

  7. Første endelige dom om insider-handel på trapperne

    DEFF Research Database (Denmark)

    Thinggaard, Frank

    1995-01-01

    Den 20. januar 1995 afsiger landsretten den første endelige dom om insider-handel. Sagen er anlagt mod den tidligere økonomichef i elektronikvirksomheden Silcon. Han står anklaget for at have solgt sine aktier i Silcon på et tidspunkt, hvor han var klar over, at selskabet havde tabt mange penge på...

  8. Den Internationale Domstols dom af 26. februar 2007 i sagen Bosnia-Herzegovina v. Yugoslavia

    DEFF Research Database (Denmark)

    Kjeldgaard-Pedersen, Astrid

    2008-01-01

    Med sin dom i Case Concerning Application of the Convention on the Prevention and Punishment of the Crime of Genocide (Bosnia-Herzegovina v. Yugoslavia) har Den Internationale Domstol i Haag1 ydet et vidtrækkende bidrag til teorien om folkedrab og fortolkningen af Folkedrabskonventionen. Efter...

  9. Size distribution of absorbing and fluorescing DOM in Beaufort Sea, Canada Basin

    Science.gov (United States)

    Gao, Zhiyuan; Guéguen, Céline

    2017-03-01

    The molecular weight (MW) of dissolved organic matter (DOM) is considered as an important factor affecting the bioavailability of organic matter and associated chemical species. Colored DOM (CDOM) MW distribution was determined, for the first time, in the Beaufort Sea (Canada Basin) by asymmetrical flow field-flow fractionation (AF4) coupled with online diode array ultra violet-visible photometer and offline fluorescence detectors. The apparent MW ranged from 1.07 to 1.45 kDa, congruent with previous studies using high performance size exclusion chromatography and tangential flow filtration. Interestingly, a minimum in MW was associated with the Pacific Summer Waters (PSW), while higher MW was associated with the Pacific Winter Waters (PWW). The Arctic Intermediate Waters (AIW) did not show any significant change in MW and fluorescence intensities distribution between stations, suggesting homogeneous DOM composition in deep waters. Three fluorescence components including two humic-like components and one protein-like component were PARAFAC-validated. With the increase of MW, protein-like fluorescence component became more dominant while the majority remained as marine/microbially derived humic-like components. Overall, it is concluded that water mass origin influenced DOM MW distribution in the Arctic Ocean.

  10. Sorption of Pyrene by Clay Minerals Coated with Dissolved Organic Matter (DOM from Landfill Leachate

    Directory of Open Access Journals (Sweden)

    Pingxiao Wu

    2015-01-01

    Full Text Available Interactions of dissolved organic matter (DOM from landfill leachate with clays could affect significantly the fate of hydrophobic organic compounds (HOCs in soils. The complexes of montmorillonite (MT and kaolinite (KL with DOM extracted from landfill leachate were prepared under controlled conditions, termed CMT and CKL, respectively. The bare clays and their complexes were characterized by powder X-ray diffraction (XRD, Fourier transform infrared (FTIR, thermogravimetry (TG, differential scanning calorimetry (DSC, and scanning electron microscopy (SEM. Batch experiments were designed to investigate the sorption behavior of pyrene onto the clays in the presence of DOM. The maximum sorption capacities of pyrene on MT, CMT, KL, and CKL were 22.18, 38.96, 42.00, and 44.99 μg·g−1, respectively, at the initial concentration of 1000 ± 150 μg·L−1. The sorption isotherms of pyrene by the bare clays followed the Henry model well, whereas the Freundlich sorption isotherm provided a better fit to the equilibrium data of the sorption by the complexes. The role of montmorillonite and kaolinite complexes with DOM in the retention of pyrene in soils was different. This may be due to the different crystal structures between montmorillonite and kaolinite.

  11. Interoperabilidad en Sistemas Domóticos Mediante Pasarela Infrarrojos-ZigBee

    National Research Council Canada - National Science Library

    Asencio, Gonzalo B; Maestre, J.M; Escaño, Juan M; Macareno, C. Martín; Molina, M.A; Camacho, E.F

    2011-01-01

    Resumen: La domótica consiste en la aplicación de técnicas provenientes de la automática industrial al hogar con objeto de ofrecer servicios que aporten, entre otras cosas, confort, seguridad y eficiencia energética a los usuarios...

  12. XVI "Baltiiski dom" : klassika v raznõhh izmerenijahh / Eteri Kekelidze

    Index Scriptorium Estoniae

    Kekelidze, Eteri, 1944-

    2006-01-01

    16. rahvusvahelisest teatrifestivalist "Baltiiski dom" Peterburis. Pikemalt vaadeldakse lavastusi : Anton Tshehhovi "Onu Vanja" (Belgia teater "Toneelhuis", lavastaja Luk Perceval), "Kolm õde" (lavastaja Rimas Tuminas), Goethe "Faust" (lavastaja Eimuntas Nekroshius), "Kosmos" (Witold Gombrowiczi romaani järgi lavastanud Jerzy Jarocki), Aleksandr Ostrovski "Mets" (Moskva Kunstiteater, lavastaja Kirill Serebrjannikov). Mainitakse, et festivalil osales ka Ugala teater Oleg Titovi lavastusega "Libahunt"

  13. Stimulus effects of ibogaine in rats trained with yohimbine, DOM, or LSD.

    Science.gov (United States)

    Palumbo, P A; Winter, J C

    1992-12-01

    The stimulus effects of ibogaine were compared with those of yohimbine, an alpha 2-adrenoceptor antagonist, 2,5-dimethoxy-4-methylamphetamine (DOM), a 5-hydroxytryptamine2 (5-HT2) agonist, and lysergic acid diethylamide (LSD), a nonspecific 5-HT agonist. Rats were trained with either yohimbine (6 mg/kg), DOM (0.6 mg/kg), or LSD (0.1 mg/kg) vs. no treatment in a two-lever discrimination task. Tests of generalization were then conducted with ibogaine. In yohimbine-trained animals, 39.7% of responses following ibogaine (15 mg/kg) were on the drug-appropriate lever, but this response level was not significantly different from no treatment-appropriate responding. A response distribution that was significantly different from responding under both drug and no treatment training conditions was observed in DOM-trained rats after administration of 15 mg/kg ibogaine. Pizotyline (BC-105) blocked all DOM-appropriate responding produced by ibogaine. In LSD-trained animals, 20 mg/kg ibogaine mimicked LSD. Pizotyline blocked LSD-appropriate responding produced by ibogaine in five of six animals. The present data suggest the involvement of 5-HT2 receptor activity, and the possibility of a 5-HT1A contribution, in the stimulus properties of ibogaine.

  14. Mucama Permitida: a identidade negra do trabalho doméstico no Brasil

    Directory of Open Access Journals (Sweden)

    Tamis Porfírio Costa Crisóstomo Ramos Nogueira

    2017-12-01

    Full Text Available O presente artigo aborda o trabalho doméstico à partir do imaginário social brasileiro, histórico e socialmente construído, oriundo de um longo período de escravidão que concebe a mulher negra em um papel de servidão e submissão análogos ao papel das mucamas, aquelas que ocupavam o âmbito doméstico e tinham como função cuidar de todo trabalho reprodutivo. Sob uma perspectiva interseccional que prioriza o três eixos de poder: raça, classe e gênero. Entende-se, neste artigo, que a condição destas trabalhadoras enquanto domésticas não escapa ao racismo, classismo e patriarcalismo tão presentes na sociedade brasileira que às confina em empregos considerados socialmente “subalternos” e não lhes dá mínimas condições de ascensão social, já que, enquanto negras, são consideradas um corpo, sem mente, capazes apenas do trabalho manual e incompetentes para o trabalho intelectual. Esta pesquisa busca explicitar a identidade do trabalho doméstico no Brasil levando em conta que este possui um perfil majoritariamente negro e uma história definida pelas relações servis de trabalho.

  15. Combined effects of DOM extracted from site soil/compost and biosurfactant on the sorption and desorption of PAHs in a soil-water system

    Energy Technology Data Exchange (ETDEWEB)

    Yu Hui, E-mail: yuhui200@uregina.ca [Environmental Systems Engineering Program, Faculty of Engineering and Applied Science, University of Regina, Regina, SK S4S 0A2 (Canada); Huang Guohe, E-mail: gordon.huang@uregina.ca [Environmental Systems Engineering Program, Faculty of Engineering and Applied Science, University of Regina, Regina, SK S4S 0A2 (Canada); An Chunjiang, E-mail: an209@uregina.ca [Environmental Systems Engineering Program, Faculty of Engineering and Applied Science, University of Regina, Regina, SK S4S 0A2 (Canada); Wei Jia, E-mail: jia.wei@iseis.org [Environmental Systems Engineering Program, Faculty of Engineering and Applied Science, University of Regina, Regina, SK S4S 0A2 (Canada)

    2011-06-15

    Highlights: {yields} The combined DOM and biosurfactant significantly enhanced desorption of PAHs. {yields} Compost DOM exhibited higher desorption enhancement capacity than the soil DOM. {yields} Competition among PAHs, DOM and biosurfactant for sorption site determined desorption of PAHs from soil. {yields} Formation of DOM-biosurfactant complex enhance desorption extent of PAHs. - Abstract: The combined effects of DOM and biosurfactant on the sorption/desorption behavior of phenanthrene (PHE) and pyrene (PYR) in soil water systems were systematically investigated. Two origins of DOMs (extracted from soil and extracted from food waste compost) and an anionic biosurfactant (rhamnolipid) were introduced. The presence of DOM in the aqueous phase could decrease the sorption of PAHs, thus influence their mobility. Desorption enhancement for both PHE and PYR in the system with compost DOM was greater than that in the soil DOM system. This is due to the differences in specific molecular structures and functional groups of two DOMs. With the co-existence of biosurfactant and DOM, partitioning is the predominant process and the desorption extent was much higher than the system with DOM or biosurfactant individually. For PHE, the desorption enhancement of combined DOM and biosurfactant was larger than the sum of DOM or biosurfactant; however desorption enhancement for PYR in the combined system was less than the additive enhancement in two individual system under low PAH concentration. This could be explained as the competition sorption among PAHs, DOM and biosurfactant. The results of this study will help to clarify the transport of petroleum pollutants in the remediation of HOCs-contaminated soils.

  16. Effect of massage on DOMS in ultramarathon runners: A pilot study.

    Science.gov (United States)

    Visconti, Lorenzo; Capra, Gianpiero; Carta, Giacomo; Forni, Corrado; Janin, Denise

    2015-07-01

    In recent years, the popularity of ultramarathons has increased. During these competitions, musculoskeletal problems are very common. Among the more frequent of those problems is the onset of muscle pain, which is defined in the literature as delayed-onset muscle soreness (DOMS). The present study aimed to collect epidemiological data regarding the onset of musculoskeletal problems during the Tor des Geants (International ultramarathon race of 330 km in length and 24,000 m in elevation difference) and to describe the effects of massage on reducing pain and overall perceived improvement in a sample of 25 athletes who complained of DOMS. Two hundred and twenty-one treatments were performed on 220 ultramarathon runners, of which 207 were males and 34 were females; the age group most represented ranged from 40 to 50 years. The most common symptom was pain, which occurred in more than 95% of cases, and the most affected area was the lower extremities (90% of subjects). In the analysed subjects, treatment with massage generated a significant (p massage, and there were no cases of worsening DOMS after massage as determined using the patient global impression of change (PGIC). The values of minimal clinically important difference (MCID) in DOMS management were calculated on the basis of the ROC curves and two other anchor-based methods in the PGIC and were 2.8-3.9 points on the NPRS. In the context analysed, massage was an effective treatment to reduce DOMS during the onset of symptoms. Copyright © 2014 Elsevier Ltd. All rights reserved.

  17. Dynamic exchanges between DOM and POM pools in coastal and inland aquatic ecosystems: A review.

    Science.gov (United States)

    He, Wei; Chen, Meilian; Schlautman, Mark A; Hur, Jin

    2016-05-01

    Dynamic exchanges between dissolved organic matter (DOM) and particulate organic matter (POM) plays a critical role in organic carbon cycling in coastal and inland aquatic ecosystems, interactions with aquatic organisms, mobility and bioavailability of pollutants, among many other ecological and geochemical phenomena. Although DOM-POM exchange processes have been widely studied from different aspects, little to no effort has been made to date to provide a comprehensive, mechanistic, and micro-spatial schema for understanding various exchange processes occurring in different aquatic ecosystems in a unified way. The phenomena occurring between DOM and POM were explained here with the homogeneous and heterogeneous mechanisms. In the homogeneous mechanism, the participating components are only organic matter (OM) constituents themselves with aggregation and dissolution involved, whereas OM is associated with other components such as minerals and particulate colloids in the heterogeneous counterpart. Besides the generally concerned processes of aggregation/dissolution and adsorption/desorption, other ecological factors such as sunlight and organisms can also participate in DOM-POM exchanges through altering the chemical nature of OM. Despite the limitation of current analytical technologies, many unknown and/or unquantified processes need to be identified to unravel the complicated exchanges of OM between its dissolved and particulate states. Based on the review of several previous mathematical models, we proposed a unified conceptual model to describe all major dynamic exchange mechanisms on the basis of exergy theory. More knowledge of dynamic DOM-POM exchanges is warranted to overcome the potential problems arising from a simple division of OM into dissolved versus particulate states and to further develop more sophisticated mathematic models. Copyright © 2016 Elsevier B.V. All rights reserved.

  18. Combined effects of DOM and biosurfactant enhanced biodegradation of polycylic armotic hydrocarbons (PAHs) in soil-water systems.

    Science.gov (United States)

    Yu, Hui; Huang, Guo-He; Xiao, Huining; Wang, Lei; Chen, Wei

    2014-09-01

    This study systematically investigated the interactive effects of dissolved organic matter (DOM) and biosurfactant (rhamnolipid) on the biodegradation of phenanthrene (PHE) and pyrene (PYR) in soil-water systems. The degradations of two polycyclic aromatic hydrocarbons (PAHs) were fitted well with first order kinetic model and the degradation rates were in proportion to the concentration of biosurfactant. In addition, the degradation enhancement of PHE was higher than that of PYR. The addition of soil DOM itself at an environmental level would inhibit the biodegradation of PAHs. However, in the system with co-existence of DOM and biosurfactant, the degradation of PAHs was higher than that in only biosurfactant addition system, which may be attributed to the formation of DOM-biosurfactant complex micelles. Furthermore, under the combined conditions, the degradation of PAH increased with the biosurfactant concentration, and the soil DOM added system showed slightly higher degradation than the compost DOM added system, indicating that the chemical structure and composition of DOM would also affect the bioavailability of PAHs. The study result may broaden knowledge of biosurfactant enhanced bioremediation of PAHs contaminated soil and groundwater.

  19. Heavy metal behavior and dissolved organic matter (DOM) characterization of vermicomposted pig manure amended with rice straw.

    Science.gov (United States)

    Zhu, Weiqin; Yao, Wu; Zhang, Zhi; Wu, Yang

    2014-11-01

    Vermicomposting is an eco-friendly method for disposing of livestock and poultry manure. In addition, dissolved organic matter (DOM) can serve as a carrier that enhances the migration and transformation of heavy metals. Here, pig manure amended with rice straw was vermicomposted with Eisenia fetida. The DOM content, molecular weight distribution, and spectroscopic properties of the amended pig manure were measured before and after vermicomposting. The Cu and Zn concentrations in the earthworms increased from 8.24 and 17.63 to 40.75 and 362.78 mg/kg separately after vermicomposting, and the earthworms also increased the heavy metal availability in the vermicompost. Relative to the DOM properties of conventional compost, the DOM molecular weight decreased and varied widely following vermicomposting, and the C/N ratio of the DOM in the vermicompost treatments decreased from 10.37 to 8.60. The Fourier transform far-infrared (FTIR) and fluorescence spectra of the DOM indicated that the amounts of oxygen-containing structures increased while the ratio of humic acid to fulvic acid decreased following vermicomposting. Accordingly, the earthworms augmented the heavy metal mitigation risk in the pig manure. This augment potentially resulted from the decreased humic acid-to-fulvic acid (HA/FA) ratio from DOM structural changes.

  20. Multivariate Analysis of Laboratory and in Situ Optical Measurements to Investigate Dom Dynamics in a Tidal Wetland

    Science.gov (United States)

    Downing, B. D.; Bergamaschi, B. A.; Fleck, J.; Kraus, T. E. C.; Fujii, R.

    2014-12-01

    The Sacramento-San Joaquin Delta (Delta) is a source of drinking water for over 30 million people in California and is an important source of carbon and nutrients for aquatic habitats in the San Francisco Estuary (SFE). The pool of dissolved organic matter (DOM) in the Delta and SFE represents a mixture of river-derived material — the integration of watershed catchment processes — and locally derived wetland DOM. Physical, biological, and chemical transformation and removal processes influence the composition of this DOM pool on timescales ranging from seconds to hours. Measuring DOM composition and concentration in estuarine environments on scales at which they are forced is impractical using traditional grab sampling and laboratory-based analysis. To better accomplish this, we deployed in-situ instrumentation to provide high frequency measurement of velocity and optically based biogeochemical proxies (absorbance, fluorescence) to investigate DOM dynamics over spring neap tidal cycles in the main slough of Brown's Island, a natural tidal wetland in the Delta. Descriptive statistics and multivariate classification of both the laboratory and in situ optical measurements (absorbance and EEMs) were obtained using parallel factor analysis (PARAFAC), principle component analysis (PCA) and linear discriminant analysis (LDA) to obtain useful high frequency optical parameters that describe DOM dynamics qualitatively and quantitatively. In this presentation we report findings from this study designed to derive and use optical indicators to continuously measure cumulative fluxes and chemical composition of wetland-derived DOM.

  1. DOM composition and transformation in boreal forest soils: The effects of temperature and organic-horizon decomposition state

    Science.gov (United States)

    O’Donnell, Jonathan A.; Aiken, George R.; Butler, Kenna D.; Guillemette, Francois; Podgorski, David C.; Spencer, Robert G. M.

    2016-01-01

    The boreal region stores large amounts of organic carbon (C) in organic-soil horizons, which are vulnerable to destabilization via warming and disturbance. Decomposition of soil organic matter (SOM) contributes to the production and turnover of dissolved organic matter (DOM). While temperature is a primary control on rates of SOM and DOM cycling, little is known about temperature effects on DOM composition in soil leachate. Here we conducted a 30 day incubation to examine the effects of temperature (20 versus 5°C) and SOM decomposition state (moss versus fibric versus amorphous horizons) on DOM composition in organic soils of interior Alaska. We characterized DOM using bulk dissolved organic C (DOC) concentration, chemical fractionation, optical properties, and ultrahigh-resolution mass spectrometry. We observed an increase in DOC concentration and DOM aromaticity in the 20°C treatment compared to the 5°C treatment. Leachate from fibric horizons had higher DOC concentration than shallow moss or deep amorphous horizons. We also observed chemical shifts in DOM leachate over time, including increases in hydrophobic organic acids, polyphenols, and condensed aromatics and decreases in low-molecular weight hydrophilic compounds and aliphatics. We compared ultrahigh-resolution mass spectrometry and optical data and observed strong correlations between polyphenols, condensed aromatics, SUVA254, and humic-like fluorescence intensities. These findings suggest that biolabile DOM was preferentially mineralized, and the magnitude of this transformation was determined by kinetics (i.e., temperature) and substrate quality (i.e., soil horizon). With future warming, our findings indicate that organic soils may release higher concentrations of aromatic DOM to aquatic ecosystems.

  2. DOM composition and transformation in boreal forest soils: The effects of temperature and organic-horizon decomposition state

    Science.gov (United States)

    O'Donnell, Jonathan A.; Aiken, George R.; Butler, Kenna D.; Guillemette, Francois; Podgorski, David C.; Spencer, Robert G. M.

    2016-10-01

    The boreal region stores large amounts of organic carbon (C) in organic-soil horizons, which are vulnerable to destabilization via warming and disturbance. Decomposition of soil organic matter (SOM) contributes to the production and turnover of dissolved organic matter (DOM). While temperature is a primary control on rates of SOM and DOM cycling, little is known about temperature effects on DOM composition in soil leachate. Here we conducted a 30 day incubation to examine the effects of temperature (20 versus 5°C) and SOM decomposition state (moss versus fibric versus amorphous horizons) on DOM composition in organic soils of interior Alaska. We characterized DOM using bulk dissolved organic C (DOC) concentration, chemical fractionation, optical properties, and ultrahigh-resolution mass spectrometry. We observed an increase in DOC concentration and DOM aromaticity in the 20°C treatment compared to the 5°C treatment. Leachate from fibric horizons had higher DOC concentration than shallow moss or deep amorphous horizons. We also observed chemical shifts in DOM leachate over time, including increases in hydrophobic organic acids, polyphenols, and condensed aromatics and decreases in low-molecular weight hydrophilic compounds and aliphatics. We compared ultrahigh-resolution mass spectrometry and optical data and observed strong correlations between polyphenols, condensed aromatics, SUVA254, and humic-like fluorescence intensities. These findings suggest that biolabile DOM was preferentially mineralized, and the magnitude of this transformation was determined by kinetics (i.e., temperature) and substrate quality (i.e., soil horizon). With future warming, our findings indicate that organic soils may release higher concentrations of aromatic DOM to aquatic ecosystems.

  3. Epileptic seizures in a descendant of Dom Pedro I Crises epilépticas em uma descendente de Dom Pedro I

    Directory of Open Access Journals (Sweden)

    Marleide da Mota Gomes

    2010-04-01

    Full Text Available Intrauterine seizure is a rare event. Genetic predisposition and trauma are possible risk factors. OBJECTIVE: To review and comment on the historical description of intrauterine events of a bastard daughter of Dom Pedro I (Maria Isabel Alcântara Brasileira - 1830-1896. METHOD: Review of historical facts about the health of Dom Pedro I's daughter according to primary and secondary historical data. RESULTS: According to historical accounts, Dom Pedro I's daughter suffered trauma during the intrauterine period that provoked intrauterine seizures. At the age of eight years, she developed self-limited and benign generalized epilepsy. Like her father, she had mood problems and also learning difficulties. CONCLUSION: Dona Maria Isabel's own report does not shown sufficient evidence to support the diagnosis of post-traumatic intrauterine seizures. Nevertheless, her family history suggests a genetic basis for her epilepsy.A convulsão intra-uterina é evento raro, sendo possíveis fatores de risco a genética e o traumatismo. OBJETIVO: Rever e comentar a descrição histórica de eventos intra-uterinas de uma filha bastarda de D. Pedro I (Maria Isabel Alcântara Brasileira - 1830-1896. MÉTODO: Revisão dos fatos históricos sobre a saúde da filha do D. Pedro I, de acordo com dados históricos primários e secundários. RESULTADOS: A filha de Dom Pedro I, de acordo com relatos históricos teria sofrido um traumatismo durante o período intra-uterino, o que provocou convulsões intra-uterinas. Na idade de oito anos a menina desenvolveu uma epilepsia generalizada limitada e benigna. Como seu pai, teve problemas do humor e, também, dificuldades de aprendizagem. CONCLUSÃO: O relato de Dona Maria Isabel não gera prova suficiente para sustentar o diagnóstico de convulsões intra-uterinas de origem traumática. Não obstante, seus antecedentes familiares sugerem uma base genética para sua epilepsia.

  4. A Priori Analysis of a Compressible Flamelet Model using RANS Data for a Dual-Mode Scramjet Combustor

    Science.gov (United States)

    Quinlan, Jesse R.; Drozda, Tomasz G.; McDaniel, James C.; Lacaze, Guilhem; Oefelein, Joseph

    2015-01-01

    In an effort to make large eddy simulation of hydrocarbon-fueled scramjet combustors more computationally accessible using realistic chemical reaction mechanisms, a compressible flamelet/progress variable (FPV) model was proposed that extends current FPV model formulations to high-speed, compressible flows. Development of this model relied on observations garnered from an a priori analysis of the Reynolds-Averaged Navier-Stokes (RANS) data obtained for the Hypersonic International Flight Research and Experimentation (HI-FiRE) dual-mode scramjet combustor. The RANS data were obtained using a reduced chemical mechanism for the combustion of a JP-7 surrogate and were validated using avail- able experimental data. These RANS data were then post-processed to obtain, in an a priori fashion, the scalar fields corresponding to an FPV-based modeling approach. In the current work, in addition to the proposed compressible flamelet model, a standard incompressible FPV model was also considered. Several candidate progress variables were investigated for their ability to recover static temperature and major and minor product species. The effects of pressure and temperature on the tabulated progress variable source term were characterized, and model coupling terms embedded in the Reynolds- averaged Navier-Stokes equations were studied. Finally, results for the novel compressible flamelet/progress variable model were presented to demonstrate the improvement attained by modeling the effects of pressure and flamelet boundary conditions on the combustion.

  5. Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis

    Science.gov (United States)

    Kim, Dong-Hyun; Kwon, Sanghoon; Byun, Sangwon; Xiao, Zhen; Park, Sean; Wu, Shwu-Yuan; Chiang, Cheng-Ming; Kemper, Byron; Kemper, Jongsook Kim

    2016-01-01

    Bile acids (BAs) are recently recognized signalling molecules that profoundly affect metabolism. Because of detergent-like toxicity, BA levels must be tightly regulated. An orphan nuclear receptor, Small Heterodimer Partner (SHP), plays a key role in this regulation, but how SHP senses the BA signal for feedback transcriptional responses is not clearly understood. We show an unexpected function of a nucleoporin, RanBP2, in maintaining BA homoeostasis through SUMOylation of SHP. Upon BA signalling, RanBP2 co-localizes with SHP at the nuclear envelope region and mediates SUMO2 modification at K68, which facilitates nuclear transport of SHP and its interaction with repressive histone modifiers to inhibit BA synthetic genes. Mice expressing a SUMO-defective K68R SHP mutant have increased liver BA levels, and upon BA- or drug-induced biliary insults, these mice exhibit exacerbated cholestatic pathologies. These results demonstrate a function of RanBP2-mediated SUMOylation of SHP in maintaining BA homoeostasis and protecting from the BA hepatotoxicity. PMID:27412403

  6. Capítulo 2. El espacio doméstico: de la vivienda al conjunto de tierras

    OpenAIRE

    Malengreau, Jacques

    2015-01-01

    El espacio en el que evoluciona y funciona la unidad doméstica tiene como eje la casa, centro doméstico de la reproducción, de la educación de sus miembros, del consumo, así como, al menos en parte, de la producción y punto de articulación de numerosas relaciones sociales y rituales en las cuales están implicados. El espacio doméstico también forma alrededor de la vivienda un archipiélago de parcelas destinadas a la agricultura o al sector pecuario que constituye un complejo conjunto de berra...

  7. MicroRNA-1301-Mediated RanGAP1 Downregulation Induces BCR-ABL Nuclear Entrapment to Enhance Imatinib Efficacy in Chronic Myeloid Leukemia Cells.

    Science.gov (United States)

    Lin, Tsung-Yao; Chen, Ku-Chung; Liu, Hsing-Jin Eugene; Liu, Ann-Jeng; Wang, Kun-Li; Shih, Chwen-Ming

    2016-01-01

    Chronic myeloid leukemia (CML) is a myeloproliferative disease. Imatinib (IM), the first line treatment for CML, is excessively expensive and induces various side effects in CML patients. Therefore, it is essential to investigate a new strategy for improving CML therapy. Our immunoblot data revealed that RanGTPase activating protein 1 (RanGAP1) protein levels increased by approximately 30-fold in K562 cells compared with those in normal cells. RanGAP1 is one of the important components of RanGTPase system, which regulates the export of nuclear protein. However, whether RanGAP1 level variation influences BCR-ABL nuclear export is still unknown. In this report, using shRNA to downregulate RanGAP1 expression level augmented K562 cell apoptosis by approximately 40% after treatment with 250 nM IM. Immunofluorescence assay also indicated that three-fold of nuclear BCR-ABL was detected. These data suggest that BCR-ABL nuclear entrapment induced by RanGAP1 downregulation can be used to improve IM efficacy. Moreover, our qRT-PCR data indicated a trend of inverse correlation between the RanGAP1 and microRNA (miR)-1301 levels in CML patients. MiR-1301, targeting the RanGAP1 3' untranslated region, decreased by approximately 100-fold in K562 cells compared with that in normal cells. RanGAP1 downregulation by miR-1301 transfection impairs BCR-ABL nuclear export to increase approximately 60% of cell death after treatment of 250 nM IM. This result was almost the same as treatment with 1000 nM IM alone. Furthermore, immunofluorescence assay demonstrated that Tyr-99 of nuclear P73 was phosphorylated accompanied with nuclear entrapment of BCR-ABL after transfection with RanGAP1 shRNA or miR-1301 in IM-treated K562 cells. Altogether, we demonstrated that RanGAP1 downregulation can mediate BCR-ABL nuclear entrapment to activate P73-dependent apoptosis pathway which is a novel strategy for improving current IM treatment for CML.

  8. Toward Radiocarbon Measurement of Individual Amino Acids in Marine Dissolved Organic Matter (DOM): Δ14C Blank Quantification for an HPLC Purification Method.

    Science.gov (United States)

    Bour, A. L.; Broek, T.; Walker, B. D.; Mccarthy, M. D.

    2014-12-01

    The presence of much of the marine dissolved organic nitrogen (DON) pool as uncharacterized, biologically recalcitrant molecules is a central mystery in the marine nitrogen cycle. Radiocarbon (Δ14C) isotopic measurements have been perhaps the most important data constraining the cycling of dissolved organic matter (DOM), but little Δ14C data specific to DON is available. Amino acids (AAs) are the major component of DON that can be isolated on a molecular level. Δ14C measurements for the operational "protein-like" fraction of DOM in the deep ocean indicate that this compound class has radiocarbon ages greater than several ocean mixing cycles, suggesting remarkable preservation of labile AAs exported from the surface. However, it is possible that the previously defined operational "protein-like" fraction may also contain non-AA material. Radiocarbon measurement of purified individual AAs would provide a more direct and reliable proxy for DON Δ14C age and cycling rate. We present here Δ14C blank characterization of an AA purification method based on HPLC, with on-line fraction collection. This method allows the recovery of unmodified AAs, but accurate measurement of small AA samples that can be extracted from DOM requires a system with extremely low Δ 14C blanks. Here we assess the impact of HPLC purification on the Δ14C age of known amino acids standards. Individual AA standards with contrasting (modern vs. dead) and well- characterized Δ14C ages were processed in a range of sample sizes. The eluted peaks were collected and dried, and measurement of their post-chromatography Δ14C content allowed for determination of the Δ14C blank by method of additions. The same protocol was applied to a mixture of six AA standards, to evaluate tailing effects in consecutive AA peaks of contrasting Δ14C age. AA standards were selected to include both Δ14C modern and dead AAs that elute both early and late in the chromatographic solvent program. We discuss implications

  9. Dissolved organic matter (DOM) export to a temperate estuary: Seasonal variations and implications of land use

    DEFF Research Database (Denmark)

    Stedmon, C. A.; Markager, S.; Søndergaard, M.

    2006-01-01

    Inputs of dissolved carbon, nitrogen, and phosphorus were assessed for an estuary and its catchment (Horsens, Denmark). Seasonal patterns in the concentrations of DOM in the freshwater supply to the estuary differed depending on the soil and drainage characteristics of the area. In streams draining......, and the percentage of catchment area used for agriculture. Colored DOM (CDOM) loading measurements were found to be a good predictor of dissolved organic carbon (DOC) loading across the different subcatchments, offering a rapid and inexpensive alternative of operationally monitoring DOC export. For all the dissolved...... nutrient inputs to the estuary, dissolved inorganic nitrogen (DIN) and dissolved organic phosphorus dominated the loadings. Although 81% of the nitrogen annually supplied to the estuary was DIN, 83% of the nitrogen exported from the estuary was dissolved organic nitrogen (DON). Results show that increasing...

  10. Violência doméstica contra o homem: de agressor a agredido

    OpenAIRE

    Dotoli, Flávia Saletti Grecco; Leão, Andreza Marques de Castro

    2016-01-01

    O presente estudo visa elucidar a existência de denúncias por parte dos homens em situação de violência doméstica, assim como, dar ênfase a negação frente às propostas de intervenções advindas no campo da saúde a partir de notificações compulsórias. Além da análise destas notificações propõe averiguar a presença ou não de políticas públicas voltadas ao acolhimento desta demanda, e de que maneira os vitimados se articularam para a legitimação de direitos no cerne da Violência Doméstica. O perc...

  11. Sistema domótico inalámbrico con portal WEB

    OpenAIRE

    Fernández Ferri, Sergio

    2017-01-01

    Memoria del TFG donde se desarrolla un sistema domótico inalámbrico con acceso a través de portal WEB mediante Arduino. El sistema permite el control de la iluminación, lectura de potencias, temperaturas y el estado de puertas. Implementa autenticación cifrada con AES128 y Diffie Hellman. Memòria del TFG on es desenvolupa un sistema domòtic sense fil amb accés a través de portal WEB mitjançant Arduino. El sistema permet el control de la il·luminació, lectura de potències, temperatures i l'...

  12. [Ultraviolet-visible (UV-Vis) and fluorescence spectral characteristics of soil dissolved organic matter (DOM) in typical agricultural watershed of Three Gorges Reservoir Region].

    Science.gov (United States)

    Wang, Qi-Lei; Jiang, Tao; Zhao, Zheng; Mu, Zhi-Jian; Wei, Shi-Qiang; Yan, Jin-Long; Liang, Jian

    2015-03-01

    As an important geo-factor to decide the environmental fate of pollutants in watershed, soil dissolved organic matter (DOM) sampled from a typical agricultural watershed in the Three Gorges Reservoir area was investigated using ultraviolet-visible (UV-Vis) and fluorescence spectroscopies, to analyze and discuss the effect of different land uses including forest, cropland, vegetable field and residence, on soil DOM geochemical characteristics. The results showed that significant differences in DOM samples amongst different land uses were observed, and DOM from forest had the highest aromaticity and humification degree, followed by DOM from cropland. Although DOM from vegetable field and residence showed the highest dissolved organic carbon (DOC) concentration (average values 0.81 g x kg(-1) and 0.89 g x kg(-1), respectively), but the aromaticity was lower indicating lower humification, which further suggested that the non-chromophoric component in these DOM samples contributed significantly to total DOM compositions. Additionally, in all DOM samples that were independent of land uses, fluorescence index (FI) values were between 1.4 (terrigenous) and 1.9 (authigenic) , evidently indicating both the allochthonous and autochthonous sources contributed to DOM characteristics. Meanwhile, r(T/C) values in most of samples were higher than 2.0, suggesting that soil DOM in this agricultural watershed was heavily affected by anthropogenic activities such as agricultural cultivation, especially, vegetable field was a good example. Additionally, sensitivities of different special spectral parameters for reflecting the differences of DOM characteristics amongst different land uses were not identical. For example, neither spectral slope ratio (S(R)) nor humification index (HIX) could clearly unveil the various geochemical characteristics of soil DOM from different sources. Thus, simple and single special spectral parameter cannot comprehensively provide the detailed information

  13. Dialogues of The Doubt: Dostoevsky's The Eternal Husband and Machado de Assis's Dom Casmurro

    Directory of Open Access Journals (Sweden)

    Andréa de Barros

    2015-10-01

    Full Text Available This article establishes a dialogic analysis of Dostoevski's The Eternal Husband (1870 and Machado de Assis's Dom Casmurro(1899, focusing on the treatment of the doubt as an aesthetic cathegory by both authors. This dialog opens room to questions related to the specificities of their prose in the context of Realism and to the signs of dialogism on the writing of the authors.

  14. Outcrop fracture characterization on suppositional planes cutting through digital outcrop models (DOMs)

    OpenAIRE

    Wang, Xin; Zou, Lejun; Ren, Yupeng; QIN, YI; Guo, Zhonghao; Shen, Xiaohua

    2017-01-01

    Conventional fracture data collection methods are usually implemented on planar surfaces or assuming they are planar; these methods may introduce sampling errors on uneven outcrop surfaces. Consequently, data collected on limited types of outcrop surfaces (mainly bedding surfaces) may not be a sufficient representation of fracture network characteristic in outcrops. Recent development of techniques that obtain DOMs from outcrops and extract the full extent of individual fractures offers the o...

  15. Los edificios de viviendas en la obra de Faustino Domínguez Coumes-Gay

    Directory of Open Access Journals (Sweden)

    Alonso Torreiro, J. Luís

    1991-12-01

    Full Text Available Not available.

    La obra del Arquitecto Faustino Domínguez Coumes-Gay, supone una de las más importantes del siglo XIX en Galicia, no tan sólo por su ingente cantidad sino también por la calidad e importancia de alguno de los edificios, junto con la variedad tipológica que presenta.

  16. Factorial analysis of the trihalomethane formation in the reaction of colloidal, hydrophobic, and transphilic fractions of DOM with free chlorine.

    Science.gov (United States)

    Platikanov, Stefan; Tauler, Roma; Rodrigues, Pedro M S M; Antunes, Maria Cristina G; Pereira, Dilson; Esteves da Silva, Joaquim C G

    2010-09-01

    This study focuses on the factors that affect trihalomethane (THMs) formation when dissolved organic matter (DOM) fractions (colloidal, hydrophobic, and transphilic fractions) in aqueous solutions were disinfected with chlorine. DOM fractions were isolated and fractionated from filtered lake water and were characterized by elemental analysis. The investigation involved a screening Placket-Burman factorial analysis design of five factors (DOM concentration, chlorine dose, temperature, pH, and bromide concentration) and a Box-Behnken design for a detailed assessment of the three most important factor effects (DOM concentration, chlorine dose, and temperature). The results showed that colloidal fraction has a relatively low contribution to THM formation; transphilic fraction was responsible for about 50% of the chloroform generation, and the hydrophobic fraction was the most important to the brominated THM formation. When colloidal and hydrophobic fraction solutions were disinfected, the most significant factors were the following: higher DOM fraction concentration led to higher THM concentration, an increase of pH corresponded to higher concentration levels of chloroform and reduced bromoform, higher levels of chlorine dose and temperature produced a rise in the total THM formation, especially of the chlorinated THMs; higher bromide concentration generates higher concentrations of brominated THMs. Moreover, linear models were implemented and response surface plots were obtained for the four THM concentrations and their total sum in the disinfection solution as a function of the DOM concentration, chlorine dose, and temperature. Overall, results indicated that THM formation models were very complex due to individual factor effects and significant interactions among the factors. In order to reduce the concentration of THMs in drinking water, DOM concentrations must be reduced in the water prior to the disinfection. Fractionation of DOM, together with an elemental

  17. Urbanization and agriculture increase exports and differentially alter elemental stoichiometry of dissolved organic matter (DOM) from tropical catchments

    DEFF Research Database (Denmark)

    Gücker, Björn; Silva, Ricky C. S.; Graeber, Daniel

    2016-01-01

    ) concentrations, but consistent effects on DOM elemental stoichiometry have not yet been reported. Here, we studied stream water DOC concentrations, catchment DOC exports, and DOM elemental stoichiometry in 20 tropical catchments at the Cerrado–Atlantic rainforest transition, dominated by natural vegetation......Many tropical biomes are threatened by rapid land-use change, but its catchment-wide biogeochemical effects are poorly understood. The few previous studies on DOM in tropical catchments suggest that deforestation and subsequent land use increase stream water dissolved organic carbon (DOC...... values in these variables throughout the year. Our results suggest that urbanization and pastoral land use exerted the strongest impacts on DOM biogeochemistry in the investigated tropical catchments and should thus be important targets for management and mitigation efforts....

  18. Characterization of DOM adsorption of CNTs by using excitation-emission matrix fluorescence spectroscopy and multiway analysis.

    Science.gov (United States)

    Peng, Mingguo; Li, Huajie; Li, Dongdong; Du, Erdeng; Li, Zhihong

    2017-06-01

    Carbon nanotubes (CNTs) were utilized to adsorb DOM in micro-polluted water. The characteristics of DOM adsorption on CNTs were investigated based on UV 254 , TOC, and fluorescence spectrum measurements. Based on PARAFAC (parallel factor) analysis, four fluorescent components were extracted, including one protein-like component (C4) and three humic acid-like components (C1, C2, and C3). The adsorption isotherms, kinetics, and thermodynamics of DOM adsorption on CNTs were further investigated. A Freundlich isotherm model fit the adsorption data well with high values of correlation. As a type of macro-porous and meso-porous adsorbent, CNTs preferably adsorb humic acid-like substances rather than protein-like substances. The increasing temperature will speed up the adsorption process. The self-organizing map (SOM) analysis further explains the fluorescent properties of water samples. The results provide a new insight into the adsorption behaviour of DOM fluorescent components on CNTs.

  19. Structural and functional properties of organic matters in extracellular polymeric substances (EPS) and dissolved organic matters (DOM) after heat pretreatment with waste sludge.

    Science.gov (United States)

    Sun, Jian; Guo, Liang; Li, Qianqian; Zhao, Yangguo; Gao, Mengchun; She, Zonglian; Wang, Guangce

    2016-11-01

    The effects of heat pretreatment on waste sludge hydrolysis were investigated in this study. Heat pretreatment was conducted at 65°C, 80°C, 100°C and 121°C for 5min, 10min, 15min, 20min, 25min and 30min. Not only analyzed the changes of SCOD (Soluble chemical oxygen demand), carbohydrate and protein, but also evaluated the structural and functional properties of organics in extracellular polymeric substances (EPS) and dissolved organic matters (DOM) by using three-dimensional excitation-emission matrix (3D-EEM) fluorescence spectroscopy with fluorescence regional integration (FRI) analysis. The SCOD in DOM increased with pretreated temperatures. The optimal heat hydrolysis temperature and time were selected by further studying the biodegradable and non-biodegradable components. After treated at 80°C for 25min, the fluorescence intensity and percent fluorescence response (Pi,n) of easily biodegradable soluble microbial by-product substance were higher than others, and little non-biodegradable fulvic acid-like substance was accumulated. Copyright © 2016 Elsevier Ltd. All rights reserved.

  20. Nuclear-Cytoplasmic Trafficking of NTF2, the Nuclear Import Receptor for the RanGTPase, Is Subjected to Regulation: e42501

    National Research Council Canada - National Science Library

    Shawn C Chafe; Jacqueline B Pierce; Dev Mangroo

    2012-01-01

    .... Treatment of mammalian cells with polysorbitan monolaurate was found to inhibit nuclear export of tRNA and proteins, which are processes dependent on RanGTP in the nucleus, but not nuclear import...

  1. Dissection of Dom34-Hbs1 reveals independent functions in two RNA quality control pathways.

    Science.gov (United States)

    van den Elzen, Antonia M G; Henri, Julien; Lazar, Noureddine; Gas, María Eugenia; Durand, Dominique; Lacroute, François; Nicaise, Magali; van Tilbeurgh, Herman; Séraphin, Bertrand; Graille, Marc

    2010-12-01

    Eukaryotic cells have several quality control pathways that rely on translation to detect and degrade defective RNAs. Dom34 and Hbs1 are two proteins that are related to translation termination factors and are involved in no-go decay (NGD) and nonfunctional 18S ribosomal RNA (rRNA) decay (18S NRD) pathways that eliminate RNAs that cause strong ribosomal stalls. Here we present the structure of Hbs1 with and without GDP and a low-resolution model of the Dom34-Hbs1 complex. This complex mimics complexes of the elongation factor and transfer RNA or of the translation termination factors eRF1 and eRF3, supporting the idea that it binds to the ribosomal A-site. We show that nucleotide binding by Hbs1 is essential for NGD and 18S NRD. Mutations in Hbs1 that disrupted the interaction between Dom34 and Hbs1 strongly impaired NGD but had almost no effect on 18S NRD. Hence, NGD and 18S NRD could be genetically uncoupled, suggesting that mRNA and rRNA in a stalled translation complex may not always be degraded simultaneously.

  2. Violência doméstica: um estudo bibliométrico

    Directory of Open Access Journals (Sweden)

    Fernanda Monteiro de Castro Bhona

    2011-01-01

    Full Text Available Este estudio tuvo como objetivo realizar un estudio bibliométrico sobre la violencia doméstica de los artículos indexados en bases de datos internacionales. La búsqueda electrónica se realizó en tres diferentes bases de datos (Web of Science, Psyc Info y Lilacs. Se relaciona con la expresión "violencia doméstica" por las palabras "hombre", "mujer", "niño", "adolescentes" y "ancianos". Se seleccionaron los artículos publicados entre los años 2006 y 2009, que fueron analizadas mediante la lectura de los títulos y resúmenes. De los 636 artículos recogidos en su mayor parte se publicó en 2006. Las revistas que se publicaron más: "Journal of Family Violence", "Violence Against Women" y "Journal of Interpersonal Violence". Las mujeres víctimas fueron el foco principal de los artículos, seguido por los niños, y la mayor parte de las publicaciones de la dirección sólo un tipo de víctima de violencia familiar. La identificación predominante del hombre como un practicante de la violencia doméstica.

  3. The influence of dissolved organic matter (DOM) on sodium regulation and nitrogenous waste excretion in the zebrafish (Danio rerio).

    Science.gov (United States)

    Al-Reasi, Hassan A; Smith, Scott D; Wood, Chris M

    2016-08-01

    Dissolved organic matter (DOM) is both ubiquitous and diverse in composition in natural waters, but its effects on the branchial physiology of aquatic organisms have received little attention relative to other variables (e.g. pH, hardness, salinity, alkalinity). Here, we investigated the effects of four chemically distinct DOM isolates (three natural, one commercial, ranging from autochthonous to highly allochthonous, all at ∼6 mg C l(-1)) on the physiology of gill ionoregulation and nitrogenous waste excretion in zebrafish acclimated to either circumneutral (7.0-8.0) or acidic pH (5.0). Overall, lower pH tended to increase net branchial ammonia excretion, net K(+) loss and [(3)H]PEG-4000 clearance rates (indicators of transcellular and paracellular permeability, respectively). However, unidirectional Na(+) efflux, urea excretion and drinking rates were unaffected. DOM sources tended to stimulate unidirectional Na(+) influx rate and exerted subtle effects on the concentration-dependent kinetics of Na(+) uptake, increasing maximum transport capacity. All DOM sources reduced passive Na(+) efflux rates regardless of pH, but exerted negligible effects on nitrogenous waste excretion, drinking rate, net K(+) loss or [(3)H]PEG-4000 clearance, so the mechanism of Na(+) loss reduction remains unclear. Overall, these actions appear beneficial to ionoregulatory homeostasis in zebrafish, and some may be related to physico-chemical properties of the DOM sources. They are very different from those seen in a recent parallel study on Daphnia magna using the same DOM isolates, indicating that DOM actions may be both species and DOM specific. © 2016. Published by The Company of Biologists Ltd.

  4. Spatial patterns of DOC concentration and DOM optical properties in a Brazilian tropical river-wetland system

    Science.gov (United States)

    Dalmagro, Higo J.; Johnson, Mark S.; de Musis, Carlo R.; Lathuillière, Michael J.; Graesser, Jordan; Pinto-Júnior, Osvaldo B.; Couto, Eduardo G.

    2017-08-01

    The Cerrado (savanna) and Pantanal (wetland) biomes of Central Western Brazil have experienced significant development activity in recent decades, including extensive land cover conversion from natural ecosystems to agriculture and urban expansion. The Cuiabá River transects the Cerrado biome prior to inundating large areas of the Pantanal, creating one of the largest biodiversity hot spots in the world. We measured dissolved organic carbon (DOC) and the optical absorbance and fluorescence properties of dissolved organic matter (DOM) from 40 sampling locations spanning Cerrado and Pantanal biomes during wet and dry seasons. In the upper, more agricultural region of the basin, DOC concentrations were highest in the rainy season with more aromatic and humified DOM. In contrast, DOC concentrations and DOM optical properties were more uniform for the more urbanized middle region of the basin between wet and dry seasons, as well as across sample locations. In the lower region of the basin, wet season connectivity between the river and the Pantanal floodplain led to high DOC concentrations, a fourfold increase in humification index (HIX) (an indicator of DOM humification), and a 50% reduction in the spectral slope (SR). Basin-wide, wet season values for SR, HIX, and FI (fluorescence index) indicated an increasing representation of terrestrially derived DOM that was more humified. Parallel factor analysis identified two terrestrially derived components (C1 and C2) representing 77% of total fluorescing DOM (fDOM). A third, protein-like fDOM component increased markedly during the wet season within the more urban-impacted region.

  5. Feminismo y mujeres migrantes en Costa Rica: articulaciones pendientes entorno al trabajo doméstico remunerado

    National Research Council Canada - National Science Library

    Fonseca Vindas, Karina

    2008-01-01

    ... a la que se pertenezca y la nacionalidad. Para efectos de este trabajo, cobra especial interés además, la necesidad de reconocer la labor doméstica como una ocupación homologable a los otros trabajos contemplados en la legislación laboral de Costa Rica, así como la urgencia de que las reivindicaciones asociadas al trabajo doméstico remunerado adquieran m...

  6. Feminismo y mujeres migrantes en Costa Rica. Articulaciones pendientes en torno al trabajo doméstico remunerado

    National Research Council Canada - National Science Library

    Vindas, Karina Fonseca

    2008-01-01

    ... a la que se pertenezca y la nacionalidad. Para efectos de este trabajo, cobra especial interés además, la necesidad de reconocer la labor doméstica como una ocupación homologable a los otros trabajos contemplados en la legislación laboral de Costa Rica, así como la urgencia de que las reivindicaciones asociadas al trabajo doméstico remunerado adquieran m...

  7. Feminismo y mujeres migrantes en Costa Rica. Articulaciones pendientes en torno al trabajo doméstico remunerado

    National Research Council Canada - National Science Library

    Karina Fonseca Vindas

    2008-01-01

    ... se pertenezca y la nacionalidad. Para efectos de este trabajo, cobra especial interés además, la necesidad de reconocer la labor doméstica como una ocupación homologable a los otros trabajos contemplados en la legislación laboral de Costa Rica, así como la urgencia de que las reivindicaciones asociadas al trabajo doméstico remunerado adquieran may...

  8. Enteric Neuron Imbalance and Proximal Dysmotility in Ganglionated Intestine of the Sox10Dom/+ Hirschsprung Mouse ModelSummary

    Directory of Open Access Journals (Sweden)

    Melissa A. Musser

    2015-01-01

    Full Text Available Background & Aims: In Hirschsprung disease (HSCR, neural crest-derived progenitors (NCPs fail to completely colonize the intestine so that the enteric nervous system is absent from distal bowel. Despite removal of the aganglionic region, many HSCR patients suffer from residual intestinal dysmotility. To test the hypothesis that inappropriate lineage segregation of NCPs in proximal ganglionated regions of the bowel could contribute to such postoperative disease, we investigated neural crest (NC-derived lineages and motility in ganglionated, postnatal intestine of the Sox10Dom/+ HSCR mouse model. Methods: Cre-mediated fate-mapping was applied to evaluate relative proportions of NC-derived cell types. Motility assays were performed to assess gastric emptying and small intestine motility while colonic inflammation was assessed by histopathology for Sox10Dom/+ mutants relative to wild-type controls. Results: Sox10Dom/+ mice showed regional alterations in neuron and glia proportions as well as calretinin+ and neuronal nitric oxide synthase (nNOS+ neuronal subtypes. In the colon, imbalance of enteric NC derivatives correlated with the extent of aganglionosis. All Sox10Dom/+ mice exhibited reduced small intestinal transit at 4 weeks of age; at 6 weeks of age, Sox10Dom/+ males had increased gastric emptying rates. Sox10Dom/+ mice surviving to 6 weeks of age had little or no colonic inflammation when compared with wild-type littermates, suggesting that these changes in gastrointestinal motility are neurally mediated. Conclusions: The Sox10Dom mutation disrupts the balance of NC-derived lineages and affects gastrointestinal motility in the proximal, ganglionated intestine of adult animals. This is the first report identifying alterations in enteric neuronal classes in Sox10Dom/+ mutants, which suggests a previously unrecognized role for Sox10 in neuronal subtype specification. Keywords: Aganglionosis, Enteric Nervous System, Neural Crest

  9. RanBP9 overexpression down-regulates phospho-cofilin, causes early synaptic deficits and impaired learning, and accelerates accumulation of amyloid plaques in the mouse brain.

    Science.gov (United States)

    Palavicini, Juan Pablo; Wang, Hongjie; Minond, Dmitriy; Bianchi, Elisabetta; Xu, Shaohua; Lakshmana, Madepalli K

    2014-01-01

    Loss of synaptic proteins and functional synapses in the brains of patients with Alzheimer's disease (AD) as well as transgenic mouse models expressing amyloid-β protein precursor is now well established. However, the earliest age at which such loss of synapses occurs, and whether known markers of AD progression accelerate functional deficits is completely unknown. We previously showed that RanBP9 overexpression leads to enhanced amyloid plaque burden in a mouse model of AD. In this study, we found significant reductions in the levels of synaptophysin and spinophilin, compared with wild-type controls, in both the cortex and the hippocampus of 5- and 6-month old but not 3- or 4-month old APΔE9/RanBP9 triple transgenic mice, and not in APΔE9 double transgenic mice, nor in RanBP9 single transgenic mice. Interestingly, amyloid plaque burden was also increased in the APΔE9/RanBP9 mice at 5-6 months. Consistent with these results, we found significant deficits in learning and memory in the APΔE9/RanBP9 mice at 5 and 6 month. These data suggest that increased amyloid plaques and accelerated learning and memory deficits and loss of synaptic proteins induced by RanBP9 are correlated. Most importantly, APΔE9/RanBP9 mice also showed significantly reduced levels of the phosphorylated form of cofilin in the hippocampus. Taken together these data suggest that RanBP9 overexpression down-regulates cofilin, causes early synaptic deficits and impaired learning, and accelerates accumulation of amyloid plaques in the mouse brain.

  10. Cascading influence of inorganic nitrogen sources on DOM production, composition, lability and microbial community structure in the open ocean.

    Science.gov (United States)

    Goldberg, S J; Nelson, C E; Viviani, D A; Shulse, C N; Church, M J

    2017-09-01

    Nitrogen frequently limits oceanic photosynthesis and the availability of inorganic nitrogen sources in the surface oceans is shifting with global change. We evaluated the potential for abrupt increases in inorganic N sources to induce cascading effects on dissolved organic matter (DOM) and microbial communities in the surface ocean. We collected water from 5 m depth in the central North Pacific and amended duplicate 20 liter polycarbonate carboys with nitrate or ammonium, tracking planktonic carbon fixation, DOM production, DOM composition and microbial community structure responses over 1 week relative to controls. Both nitrogen sources stimulated bulk phytoplankton, bacterial and DOM production and enriched Synechococcus and Flavobacteriaceae; ammonium enriched for oligotrophic Actinobacteria OM1 and Gammaproteobacteria KI89A clades while nitrate enriched Gammaproteobacteria SAR86, SAR92 and OM60 clades. DOM resulting from both N enrichments was more labile and stimulated growth of copiotrophic Gammaproteobacteria (Alteromonadaceae and Oceanospirillaceae) and Alphaproteobacteria (Rhodobacteraceae and Hyphomonadaceae) in weeklong dark incubations relative to controls. Our study illustrates how nitrogen pulses may have direct and cascading effects on DOM composition and microbial community dynamics in the open ocean. © 2017 Society for Applied Microbiology and John Wiley & Sons Ltd.

  11. Application of isotope dilution method for measuring bioavailability of organic contaminants sorbed to dissolved organic matter (DOM)

    Energy Technology Data Exchange (ETDEWEB)

    Delgado-Moreno, Laura, E-mail: laura.delgado@eez.csic.es; Wu, Laosheng; Gan, Jay

    2015-08-15

    Natural waters such as surface water and sediment porewater invariably contain dissolved organic matter (DOM). Association of strongly hydrophobic contaminants (HOCs) with DOM leads to decreased toxicity and bioavailability, but bioavailability of DOM-sorbed HOCs is difficult to measure. Current methods to estimate bioavailability of HOCs in water are based on only the freely dissolved concentration (C{sub free}). The ignorance of the exchangeable fraction of HOCs sorbed on DOM may result in an underestimation of the toxicity potential of HOCs to aquatic organisms. Here we explore the applicability of an isotope dilution method (IDM) to measuring the desorption fraction of DOM-sorbed pyrene and bifenthrin and determining their exchangeable pool (E) as an approximation of bioavailability. E values, expressed as percentage of the total concentration, ranged between 0.80 and 0.92% for pyrene and 0.74 and 0.85% for bifenthrin, depending primarily on the amount of chemical in the freely dissolved form. However, between 34 and 78% of the DOM-sorbed pyrene was exchangeable. This fraction ranged between 23% and 82% for bifenthrin. The ability of IDM to predict bioavailability was further shown from a significant relationship (r{sup 2} > 0.72, P < 0.0001) between E and bioaccumulation into Daphnia magna. Therefore, IDM may be used to improve the bioavailability measurement and risk assessment of HOCs in aquatic systems.

  12. Volvo ja Ikea endine tegevjuht Göran Carstedt : Tänapäevane (personali)juhtimine peab sisaldama eeskätt looduslähedast mõtteviisi / Göran Carstedt ; interv. Tiina Saar

    Index Scriptorium Estoniae

    Carstedt, Göran

    2008-01-01

    Juhtimiskonsultant ning Organisatsioonilise Õppimise Ühingu eestvedaja ja arendaja Göran Carsedt vastab küsimustele, mis puudutavad ettevõtte tegevust personali tööle pühendumise parendamiseks, ettevõtte jätkusuutlikku juhtimist ja tootlikkust, majanduslanguse mõju ettevõtete personalipoliitikale, talendijuhtimist, väikeste ettevõttete ellujäämist majanduslanguse ajal, IKEA kui hea tööandja mainet ning jätkusuutlikku personaliarendajat. Lisa: Jätkusuutlik juhtimine Rootsi moodi

  13. Reduction of exportin 6 activity leads to actin accumulation via failure of RanGTP restoration and NTF2 sequestration in the nuclei of senescent cells

    Energy Technology Data Exchange (ETDEWEB)

    Park, Su Hyun; Park, Tae Jun; Lim, In Kyoung, E-mail: iklim@ajou.ac.kr

    2011-04-15

    We have previously reported that G-actin accumulation in nuclei is a universal phenomenon of cellular senescence. By employing primary culture of human diploid fibroblast (HDF) and stress-induced premature senescence (SIPS), we explored whether the failure of actin export to cytoplasm is responsible for actin accumulation in nuclei of senescent cells. Expression of exportin 6 (Exp6) and small G-protein, Ran, was significantly reduced in the replicative senescence, but not yet in SIPS, whereas nuclear import of actin by cofilin was already increased in SIPS. After treatment of young HDF cells with H{sub 2}O{sub 2}, rapid reduction of nuclear RanGTP was observed along with cytoplasmic increase of RanGDP. Furthermore, significantly reduced interaction of Exp6 with RanGTP was found by GST-Exp6 pull-down analysis. Failure of RanGTP restoration was accompanied with inhibition of ATP synthesis and NTF2 sequestration in the nuclei along with accordant change of senescence morphology. Indeed, knockdown of Exp6 expression significantly increased actin molecule in the nuclei of young HDF cells. Therefore, actin accumulation in nuclei of senescent cells is most likely due to the failure of RanGTP restoration with ATP deficiency and NTF2 accumulation in nuclei, which result in the decrease of actin export via Exp6 inactivation, in addition to actin import by cofilin activation.

  14. Formation of a Trimeric Xpo1-Ran[GTP]-Ded1 Exportin Complex Modulates ATPase and Helicase Activities of Ded1.

    Directory of Open Access Journals (Sweden)

    Glenn Hauk

    Full Text Available The DEAD-box RNA helicase Ded1, which is essential in yeast and known as DDX3 in humans, shuttles between the nucleus and cytoplasm and takes part in several basic processes including RNA processing and translation. A key interacting partner of Ded1 is the exportin Xpo1, which together with the GTP-bound state of the small GTPase Ran, facilitates unidirectional transport of Ded1 out of the nucleus. Here we demonstrate that Xpo1 and Ran[GTP] together reduce the RNA-stimulated ATPase and helicase activities of Ded1. Binding and inhibition of Ded1 by Xpo1 depend on the affinity of the Ded1 nuclear export sequence (NES for Xpo1 and the presence of Ran[GTP]. Association with Xpo1/Ran[GTP] reduces RNA-stimulated ATPase activity of Ded1 by increasing the apparent KM for the RNA substrate. Despite the increased KM, the Ded1:Xpo1:Ran[GTP] ternary complex retains the ability to bind single stranded RNA, suggesting that Xpo1/Ran[GTP] may modulate the substrate specificity of Ded1. These results demonstrate that, in addition to transport, exportins such as Xpo1 also have the capability to alter enzymatic activities of their cargo.

  15. A PARAFAC-based long-term assessment of DOM in a multi-coagulant drinking water treatment scheme.

    Science.gov (United States)

    Sanchez, Nancy P; Skeriotis, Andrew T; Miller, Christopher M

    2014-01-01

    A parallel factor (PARAFAC) analysis approach was used to study the character and composition of dissolved organic matter (DOM) in a multicoagulant (two aluminum-based coagulants) full scale drinking water treatment plant. A three year, long-term assessment was conducted based on deconstruction of the excitation-emission matrices (EEM) of over 1000 water samples collected before and after parallel coagulation treatment basins. Two humic moieties and a protein-like group were identified in the raw and treated waters. Apportionment of fluorophores was established using a novel approach based on the overall fluorescence intensity (OFI) of PARAFAC components. Uncorrected matrix correlation (UMC) revealed minimal changes of the fluorescence moieties after treatment (UMC > 0.98), and a comparable effect of both coagulants on the structure (UMC > 0.99) and distribution of these groups. Coagulation increased the proportion of the protein-like fluorophore and preferentially removed a humic-like group irrespective of the coagulant. Preference for this moiety was supported by a coagulant-affinity factor derived from the association between PARAFAC components after treatment. The suitability of a PARAFAC-based approach for coagulant evaluation/selection was demonstrated when compared to a dissolved organic carbon (DOC)-based criterion. This paper contributes to the understanding of the behavior of PARAFAC components in water treatment processes and presents several approaches for the future monitoring and control of coagulation at full scale treatment facilities.

  16. Comparison of RANS and IDDES solutions for turbulent flow and heat transfer past a backward-facing step

    Science.gov (United States)

    Smirnov, E. M.; Smirnovsky, A. A.; Schur, N. A.; Zaitsev, D. K.; Smirnov, P. E.

    2017-10-01

    Numerical simulations were carried out under conditions of the benchmark-quality experiments of Vogel&Eaton (1985), where nominally 2D fluid dynamics and heat transfer past a backward-facing step in a channel with expansion ratio of 1.25 was investigated at the Reynolds number of 28,000 (based on the step height and the upstream centreline velocity). Comparative computations were performed using an in-house finite-volume code SINF/Flag-S and the ANSYS Fluent, running the codes with same grids. Two approaches were used for turbulence modelling. First, the Menter SST turbulence model was used to perform refined 2D and 3D RANS steady-state computations. The 3D analysis was undertaken to evaluate influence of boundary layers developing on the sidewalls of the experimental channel. The data obtained has resulted in the conclusion that the side wall effects disturbing spanwise uniformity of wall friction and heated wall temperature in the test configuration were of the same order or less than the skin friction coefficient and the Stanton number measurement errors. Then, 3D time-dependent computations were carried out using the vortex-resolving IDDES method being a hybridization of RANS and LES. The IDDES results obtained with the two codes are in a satisfactory agreement, especially for the finer grid of 17.3 million cells. Comparing with the experimental data, the IDDES approach produces the best agreement for the wall friction, whereas the RANS solutions show superiority in predictions of the local Stanton number distribution.

  17. The proliferation marker pKi-67 organizes the nucleolus during the cell cycle depending on Ran and cyclin B.

    Science.gov (United States)

    Schmidt, Mirko H H; Broll, Rainer; Bruch, Hans-Peter; Bögler, Oliver; Duchrow, Michael

    2003-01-01

    The proliferation marker pKi-67 ('Ki-67 antigen') is commonly used in clinical and research pathology to detect proliferating cells, as it is only expressed during cell-cycle progression. Despite the fact that this antigen has been known for nearly two decades, there is still no adequate understanding of its function. This study has therefore identified proteins that interact with pKi-67, using a yeast two-hybrid system. A mammalian two-hybrid system and immunoprecipitation studies were used to verify these interactions. Among other cell-cycle regulatory proteins, two binding partners associated with the small GTPase Ran were identified. In addition, DNA-structural and nucleolus-associated proteins binding to pKi-67 were found. Moreover, it was demonstrated that the N-terminal domain of pKi-67 is capable of self-binding to its own repeat region encoded by exon 13. Since RanBP, a protein involved in the transport of macromolecules over the nuclear lamina, was found to be a binding partner, a possible effect of pKi-67 on the localization of cell-cycle regulatory proteins was proposed. To test this hypothesis, a tetracycline-responsive gene expression system was used to induce the pKi-67 fragments previously used for the two-hybrid screens in HeLa cells. Subsequent immunostaining revealed the translocation of cyclin B1 from cytoplasm to nucleoli in response to this expression. It is suggested that pKi-67 is a Ran-associated protein with a role in the disintegration and reformation of the nucleolus and thereby in entry into and exit from the M-phase. Copyright 2002 John Wiley & Sons, Ltd.

  18. Optical and molecular characterization of dissolved organic matter (DOM) in the Arctic ice core and the underlying seawater (Cambridge Bay, Canada): Implication for increased autochthonous DOM during ice melting.

    Science.gov (United States)

    Retelletti Brogi, Simona; Ha, Sun-Yong; Kim, Kwanwoo; Derrien, Morgane; Lee, Yun Kyung; Hur, Jin

    2018-02-01

    Sea ice contains a large amount of dissolved organic matter (DOM), which can be released into the ocean once it melts. In this study, Arctic sea ice DOM was characterized for its optical (fluorescence) properties as well as the molecular sizes and composition via size exclusion chromatography and Fourier transformation ion cyclotron resonance mass spectrometry (FT-ICR MS). Ice cores were collected along with the underlying seawater samples in Cambridge Bay, an Arctic area experiencing seasonal ice formation. The ice core samples revealed a marked enrichment of dissolved organic carbon (DOC) compared to the seawater counterparts (up to 6.2 times greater). The accumulation can be attributed to in situ production by the autotrophic and heterotrophic communities. Fluorescence excitation emission matrices (EEMs) elaborated with parallel factor analysis (PARAFAC) evidenced the prevalence of protein-like substances in the ice cores, which likely results from in situ production followed by accumulation in the ice. Size exclusion chromatography further revealed the in situ production of all DOM size fractions, with the exception of the humic substance fraction. The majority of DOM in both the ice and seawater consists of low molecular weight compounds (<350 Da) probably derived by the microbial degradation/transformation of freshly produced DOM. Molecular characterization also supported the in situ production of DOM and highlighted the marked difference in molecular composition between sea ice and seawater. This study provides new insights into the possible role of sea ice DOM in the Arctic carbon cycle under climate change. Copyright © 2017 Elsevier B.V. All rights reserved.

  19. Surface Mechanical and Rheological Behaviors of Biocompatible Poly((D,L-lactic acid-ran-glycolic acid)-block-ethylene glycol) (PLGA-PEG) and Poly((D,L-lactic acid-ran-glycolic acid-ran-ε-caprolactone)-block-ethylene glycol) (PLGACL-PEG) Block Copolymers at the Air-Water Interface

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyun Chang; Lee, Hoyoung; Khetan, Jawahar; Won, You-Yeon [Purdue

    2016-02-01

    Air–water interfacial monolayers of poly((d,l-lactic acid-ran-glycolic acid)-block-ethylene glycol) (PLGA–PEG) exhibit an exponential increase in surface pressure under high monolayer compression. In order to understand the molecular origin of this behavior, a combined experimental and theoretical investigation (including surface pressure–area isotherm, X-ray reflectivity (XR) and interfacial rheological measurements, and a self-consistent field (SCF) theoretical analysis) was performed on air–water monolayers formed by a PLGA–PEG diblock copolymer and also by a nonglassy analogue of this diblock copolymer, poly((d,l-lactic acid-ran-glycolic acid-ran-caprolactone)-block-ethylene glycol) (PLGACL–PEG). The combined results of this study show that the two mechanisms, i.e., the glass transition of the collapsed PLGA film and the lateral repulsion of the PEG brush chains that occur simultaneously under lateral compression of the monolayer, are both responsible for the observed PLGA–PEG isotherm behavior. Upon cessation of compression, the high surface pressure of the PLGA–PEG monolayer typically relaxes over time with a stretched exponential decay, suggesting that in this diblock copolymer situation, the hydrophobic domain formed by the PLGA blocks undergoes glass transition in the high lateral compression state, analogously to the PLGA homopolymer monolayer. In the high PEG grafting density regime, the contribution of the PEG brush chains to the high monolayer surface pressure is significantly lower than what is predicted by the SCF model because of the many-body attraction among PEG segments (referred to in the literature as the “n-cluster” effects). The end-grafted PEG chains were found to be protein resistant even under the influence of the “n-cluster” effects.

  20. Surface Mechanical and Rheological Behaviors of Biocompatible Poly((D,L-lactic acid-ran-glycolic acid)-block-ethylene glycol) (PLGA-PEG) and Poly((D,L-lactic acid-ran-glycolic acid-ran-ε-caprolactone)-block-ethylene glycol) (PLGACL-PEG) Block Copolymers at the Air-Water Interface.

    Science.gov (United States)

    Kim, Hyun Chang; Lee, Hoyoung; Khetan, Jawahar; Won, You-Yeon

    2015-12-29

    Air-water interfacial monolayers of poly((D,L-lactic acid-ran-glycolic acid)-block-ethylene glycol) (PLGA-PEG) exhibit an exponential increase in surface pressure under high monolayer compression. In order to understand the molecular origin of this behavior, a combined experimental and theoretical investigation (including surface pressure-area isotherm, X-ray reflectivity (XR) and interfacial rheological measurements, and a self-consistent field (SCF) theoretical analysis) was performed on air-water monolayers formed by a PLGA-PEG diblock copolymer and also by a nonglassy analogue of this diblock copolymer, poly((D,L-lactic acid-ran-glycolic acid-ran-caprolactone)-block-ethylene glycol) (PLGACL-PEG). The combined results of this study show that the two mechanisms, i.e., the glass transition of the collapsed PLGA film and the lateral repulsion of the PEG brush chains that occur simultaneously under lateral compression of the monolayer, are both responsible for the observed PLGA-PEG isotherm behavior. Upon cessation of compression, the high surface pressure of the PLGA-PEG monolayer typically relaxes over time with a stretched exponential decay, suggesting that in this diblock copolymer situation, the hydrophobic domain formed by the PLGA blocks undergoes glass transition in the high lateral compression state, analogously to the PLGA homopolymer monolayer. In the high PEG grafting density regime, the contribution of the PEG brush chains to the high monolayer surface pressure is significantly lower than what is predicted by the SCF model because of the many-body attraction among PEG segments (referred to in the literature as the "n-cluster" effects). The end-grafted PEG chains were found to be protein resistant even under the influence of the "n-cluster" effects.

  1. Consumo de alcohol y violencia doméstica contra las mujeres: un estudio con estudiantes universitarias de México Consumo de álcool e violência doméstica contra a mulher: estudo com estudantes universitárias mexicanas Alcohol consumption and domestic violence against women: a study with university students from mexico

    Directory of Open Access Journals (Sweden)

    José Manuel Herrera Paredes

    2010-06-01

    parceiros consomem álcool, especialmente em reuniões sociais. Os resultados apontaram também que 41,1% não conhecem seus direitos em relação à violência doméstica. Dessa forma, são necessárias ações de conscientização das mulheres sobre seus direitos e possibilidades de ajuda legal em casos de violência.Domestic violence against women and alcohol consumption are considered public health problems. This descriptive study aimed at determining the occurrence of domestic violence against women enrolled in the Nursing and Midwifery Program at the University of Celaya, Mexico and its relation with alcohol consumption by their partners. A sample of 73 students was randomly selected. Data were collected using the CASIQUE-QUEJ TUN questionnaire and analyzed using SPSS. With respect to physical violence, results showed that 91.9% were not maltreated by their partners. Regarding alcohol consumption, 57.5% of the women interviewed and 67.1% of their partners drank alcohol, especially at social events. Results also showed that 41.1% of the subjects did not know about their rights in cases of domestic violence. Thus, there is a need for actions which increase women’s awareness of their rights and the possibilities of legal support in cases of violence.

  2. Burns in the domestic environment: characteristics and circumstances of accidents Quemaduras en ambiente doméstico: características y circunstancias del accidente Queimaduras em ambiente doméstico: características e circunstâncias do acidente

    Directory of Open Access Journals (Sweden)

    Tatiane Meda Vendrusculo

    2010-06-01

    Full Text Available This study characterizes burn accidents in the domestic environment and identifies the circumstances of accidents affecting children, adults or elderly people who need supervision or care. Demographic data and burn characteristics of 61 domestic environment burn victims were collected. The family members of 13 children and one aged adult, who needed supervision or special care, were selected to answer a semi-structured interview. Two thematic groups were identified: social and environmental factors that might have contributed to the burn accidents and circumstances involving the accidents. Risk factors were: low socioeconomic and educational levels of mothers and those responsible for the children at the moment of the accident, small houses considering the number of occupants and unsafe kitchen equipment. Although cases of domestic violence were not identified there was neglect from caregivers. Health professionals should be attentive and investigate the circumstances of accidents involving vulnerable individuals.Este estudio tuvo como objetivos caracterizar los accidentes por quemaduras, ocurridos en ambiente doméstico, e identificar las circunstancias de esos accidentes cuando afectaron niños, adultos o ancianos que necesitaban de supervisión. Fueron recolectados datos demográficos y sobre el trauma de 61 víctimas de quemaduras en ambiente doméstico. De esas, 13 niños y un anciano, con necesidad de supervisión o cuidado especial, tuvieron los familiares seleccionados para entrevista semiestructurada. Fueron identificados dos núcleos temáticos: factores que pueden haber contribuido para la ocurrencia de accidentes por quemaduras: sociales y ambientales y, circunstancias que envolvieron el accidente. Los factores de riesgo fueron: bajo nivel socioeconómico y de instrucción de las madres responsables por el niño en el momento del accidente, habitaciones pequeñas para el número de residentes, y, equipamientos de cocina precarios. No

  3. c9RAN translation: a potential therapeutic target for the treatment of amyotrophic lateral sclerosis and frontotemporal dementia.

    Science.gov (United States)

    Gendron, Tania F; Cosio, Danielle M; Petrucelli, Leonard

    2013-09-01

    A hexanucleotide (GGGGCC) repeat expansion within a non-coding region of the C9ORF72 gene is the most common mutation associated with both frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). Elucidating how these expanded repeats (GGGGCCexp) cause 'c9FTD/ALS' has since become an important goal of the FTD/ALS field. GGGGCCexp transcripts aggregate into discrete nuclear structures, termed RNA foci. This phenomenon, observed in various repeat expansion disorders, is associated with RNA-binding protein sequestration. Of note, recent findings show that GGGGCCexp transcripts also succumb to an alternative fate: repeat-associated non-ATG translation (RAN translation). This unconventional mode of translation, which occurs in the absence of an initiating codon, results in the production of polyGA, polyGP and polyGR peptides. Antibodies generated against these peptides detect high molecular weight, insoluble material in brain homogenates, as well as neuronal inclusions throughout the central nervous system of c9FTD/ALS cases. Given that both foci formation and RAN translation in c9FTD/ALS require the synthesis of GGGGCCexp RNA, therapeutic strategies that target these transcripts and result in their neutralization or degradation could effectively block these two potential pathogenic mechanisms and provide a much needed treatment for c9FTD/ALS.

  4. Métodos de control en sistemas domóticos: últimas tendencias en sistemas distribuidos

    Directory of Open Access Journals (Sweden)

    Moreno Navarro, I.

    1999-02-01

    Full Text Available Control systems lie amongst the most difficult issues to be tackled when it comes to designing home automation systems. Two classical tendencies may be considered to solve this problem. The first one consists of a centralised control system, whereas the second option advocates for a distributed network, where piece would take up certain responsibilities in the control of the whole system. In this paper we analyse some of the latest developments as regards programming distributed networks, focusing on home automation, specially Java and the latest Jini environments have dramatically improved the potential of such kind of distributed systems, thanks to them, it is possible to build a heterogeneous network including devices from different brands which work in collaborative systems, thus avoiding complex configurations.

    Uno de los aspectos más delicados a la hora de diseñar un sistema domótico es el que se refiere al modelo de control que deseamos establecer. Podemos considerar dos tendencias clásicas: la que trata de establecer un control centralizado del sistema y la que propone un control mucho más descentralizado, donde cada aparato seria responsable de cierta parte de la gestión del control ejercido sobre toda la red. En este articulo tratamos de profundizar en las últimas novedades aparecidas en el campo de la programación de los controladores asociados a una red domótica, en particular Java y el más reciente Jini, que aportan una serie de soluciones que facilitan la compatibilidad entre dispositivos de distintos fabricantes y apuestan claramente por una arquitectura de tipo distribuido, dotando a las redes domóticas de una flexibilidad y un potencial de crecimiento inusitados.

  5. Trabalho doméstico: desafios para o trabalho decente Domestic work: challenges for decent work

    Directory of Open Access Journals (Sweden)

    Solange Sanches

    2009-12-01

    Full Text Available Este artigo apresenta um panorama da situação das trabalhadoras domésticas e traz algumas questões relativas à sua dimensão no mundo e no Brasil, suas condições de trabalho e importância para o funcionamento geral dos mercados de trabalho e dos domicílios. Buscase mostrar a relevância que tem o conceito de trabalho decente, promovido pela Organização Internacional do Trabalho (OIT, para o trabalho doméstico e a equiparação de seus direitos no trabalho aos do conjunto das trabalhadoras e dos trabalhadores. Ressalta-se a oportunidade da discussão na próxima Conferência Internacional do Trabalho da OIT, em 2010, na qual o tema é ponto de pauta com vistas à elaboração de um instrumento internacional de proteção ao trabalho domésticoThis article presents an overview of the situation of the domestic workers and focuses on some issues related to its dimension in the world and in Brazil, to their conditions of work and its importance to the labor market and to the households. We aim to demonstrate the relevance of the concept of decent work, promoted by ILO - International Labor Organization, for the domestic work and the need to extend their rights to level them with the other workers. It also highlights the opportunity offered by the next International Labor Conference, in 2010, when one of the issues of the agenda is to discuss the crafting and adoption of international labor standards in the form of a specific convention or recommendation

  6. Diseño de un prototipo para el reciclaje de aceites domésticos

    OpenAIRE

    López Tamames, Borja

    2008-01-01

    Este proyecto, tiene como objetivo, la creación de una máquina prototipo para la recogida de aceites domésticos usados. Actualmente existen máquinas separadoras de agua y aceite, pero estas se utilizan para uso industrial. Existen también contenedores, para la recolección de aceites, pero en estos se vierten todo tipo de aceites, tanto vegetales como minerales, y no se diferencian las mezclas que se vierten en ellos, reduciendo así su efectividad. La idea de diseñar una máqu...

  7. Modeling the HTML DOM and Browser API in Static Analysis of JavaScript Web Applications

    DEFF Research Database (Denmark)

    Jensen, Simon Holm; Madsen, Magnus; Møller, Anders

    2011-01-01

    such technologies to the domain of JavaScript web applications is challenging. In this paper, we discuss the challenges, which include the dynamic aspects of JavaScript and the complex interactions between JavaScript, HTML, and the browser. From this, we present the first static analysis that is capable...... of reasoning about the flow of control and data in modern JavaScript applications that interact with the HTML DOM and browser API. One application of such a static analysis is to detect type-related and dataflow-related programming errors. We report on experiments with a range of modern web applications...

  8. La violencia doméstica infantojuvenil en la perspectiva de los agentes comunitarios de salud

    OpenAIRE

    Gebara, Carla Ferreira De Paula [UNIFESP; Lourenço, Lélio Moura; Ronzani, Telmo Mota [UNIFESP

    2013-01-01

    A presente pesquisa teve como objetivo analisar as crenças dos Agentes Comunitários de Saúde (ACSs) de um município de Minas Gerais a respeito da violência doméstica (VD) contra crianças e adolescentes. Participaram todos os trinta ACSs do município, os quais, num primeiro momento, responderam a um questionário autoaplicável, estruturado, individual e anônimo. Num segundo momento, os ACSs foram convidados a participar de um grupo focal. Os dados qualitativos foram analisados por meio da técni...

  9. ENTRE RETRATOS E MEMÓRIAS: AS ILUSTRAÇÕES DE POTY EM DOM CASMURRO

    Directory of Open Access Journals (Sweden)

    Cilene Margarete Pereira

    2010-01-01

    Full Text Available En la edición de Dom Casmurro (colección "Clásicos Brasileños", los grabados del artista Poty revelan, en parte, adhesión al discurso del narrador, puntuando la imagen dudosa de Capitu. Sin embargo, en al menos dos ilustraciones, Poty señala otra perspectiva, capaz de descubrir la visión borrosa y amargado el narrador Bento Santiago en relación con la amiga de la infancia.

  10. A violência doméstica na perspetiva de mulheres que a viveram

    OpenAIRE

    Lopes,Manuel José; Gemito, Laurência; Pinheiro, Felicia Tavares; Magalhães, Dulce; Marques,Maria de Fátima; Serra, Isaura; Zangão, Otilia

    2014-01-01

    Introdução: Sendo a violência doméstica um processo altamente complexo e intimista, uma das melhores formas de a compreender, é dar voz aqueles que a vivem, de modo a que seja possível objetivar as experiências subjetivas. Objetivo: Compreender o sofrimento das mulheres vítimas de violência. Método e Técnicas: Foi considerada uma amostra intencional com critério reputacional de 21 mulheres que estavam em casa abrigo ou na comunidade. Os dados foram recolhidos por entrevistas feitas com audio...

  11. Domótica, una nueva propuesta para ámbitos inteligentes

    OpenAIRE

    De Vincenzi, Marcelo; Cardacci, Dario; Mastriani, Mario

    2000-01-01

    En este trabajo se presenta una original aplicación de la Domótica, consistente en el control de elementos, y la administración de dispositivos desde cualquier lugar del mundo sobre el protocolo TCP/IP. En este caso particular, está orientado a la seguridad, monitoreo y confort de distintos ámbitos (oficinas, casas, hospitales, etc.). El aporte de este estudio consiste en una novel implemen-tación del control de la totalidad de las funciones llevadas a cabo en forma cotidiana en los mencio-na...

  12. Portal web de una tienda virtual de productos para animales domésticos

    OpenAIRE

    PEINADO ABAD, PABLO

    2015-01-01

    [ES] Este proyecto se basa en el desarrollo de una tienda virtual de productos para animales domésticos utilizando el framework de PHP Yii Framework y el sistema gestor de bases de datos MySQL. También, como en todo desarrollo web, se hace uso del lenguaje de marcado de hipertexto HTML y de las hojas de estilo en cascada CSS. El desarrollo contempla la gestión de un catálogo de productos, la cesta de la compra y pedidos, así como la capacidad de gestionar las cuentas de usuario...

  13. Dom Quixote e os moinhos de vento na América Latina

    OpenAIRE

    Quijano Aníbal

    2005-01-01

    NESTE TEXTO, discutem-se a formação da América Latina, seu lugar e seu papel na configuração da Colonialidade do poder como padrão de poder mundialmente dominante, e na emergência da Europa Ocidental como centro de controle desse padrão de poder. Discutem-se também o Eurocentrismo, seu modo hegemônico de produção e de controle do conhecimento, distante da e oposto à herança de Dom Quixote.

  14. Identidades y tecnologías desde el escenario doméstico

    Directory of Open Access Journals (Sweden)

    Lorena Gartner Isaza

    2010-06-01

    ciencias sociales y humanas. Este artículo reflexiona en torno a la inserción de internet en los escenarios domésticos y los impactos que ello puede tener en las identidades personales y sociales de los miembros de las familias y en las transformaciones que pueden derivarse para la comunicación cara a cara en el hábitat familiar. Finalmente, se señalan algunas posibilidades para el desarrollo de las ciencias humanas y sociales en relación con esta temática.

  15. Rodnoi dom : [luuletused] / Lydia Koidula ; lühibiograafia: S. S. [Svetlan Semenenko

    Index Scriptorium Estoniae

    Koidula, Lydia, pseud., 1843-1886

    1999-01-01

    Sisu: Rodnoi dom ; Serdtse materi / tlk. Vs. Rozhdestvenski ; Ossennije dumõ / per. M. Zamahhovskaja ; Pesn Estonii / tlk. Nora Javorskaja ; Moja Estonija - moja ljubov / tlk. Bronislav Kezhun ; Vot rodina tvoja / tlk. Pavel Zheleznov ; Dolg pesni / tlk. Nora Javorskaja ; Predsmertnoje slovo - Estonii / tlk. P. Zheleznov. Orig.: Kodu : "Meil aia-äärne tänavas..." ; Emasüda ; Sügisemõtted ; Eesti laul [et kõla sa...] ; Mu isamaa on minu arm ; See on su isamaa! ; Laulu kohus ; Enne surma Eestimaale

  16. Un uso eficiente del agua doméstica : tratamiento de las aguas grises

    OpenAIRE

    Castro Montilla, María

    2015-01-01

    El trabajo expuesto a continuación plantea la reutilización de las aguas grises como un método novedoso para conseguir un uso eficiente del agua en el ámbito doméstico, llevando consigo un ahorro del recurso para conseguir, por una parte, la reducción de los costes debido a un consumo menor del agua; y por otra, una reducción de la huella ecológica para contribuir a un progreso hacia una arquitectura más sostenible y solidaria con el medioambiente. Se desarrollarán conceptos que abarcan, d...

  17. A comparative study of the effects of infrared radiation and warm-up exercises in the management of DOMS

    Directory of Open Access Journals (Sweden)

    Ayoola I Aiyegbusi

    2016-01-01

    Full Text Available Introduction: Delayed onset muscle soreness (DOMS is associated with temporary morbidity as a result of pain, soreness, and reduced muscular performance that affects the overall performance of the individual. Several interventional modalities have been studied without a conclusive evidence of efficacy. Objective: This study was carried out as part of a continuous attempt to find an effective and quick relief for DOMS. The study investigated the comparative effects of warm-up exercises and infrared radiation in ameliorating the symptoms associated with DOMS. Materials and Methods: Sixty volunteer subjects between the age of 16 years and 35 years had DOMS induced in the left biceps brachii muscle. They were randomized into three groups with 20 subjects in each group. The groups were allocated as follows: Group A as control that received no treatment, Group B had a bout of warm-up exercises consisting of 10 sets of maximal elbow flexion and extension after which DOMS was experimentally induced, and Group C had infrared radiation for 20 min  after which DOMS was experimentally induced. Assessment for muscle soreness, pain, and joint range of motion (ROM was carried out immediately after inducing DOMS and it was repeated 24 h and 48 h later using the Numerical Pain Rating Scale (NPRS, deep palpation (DP, and goniometry, respectively. Results: The infrared group (Group C had significantly lower scores on NPRS and DP throughout the 3 days compared with the control while the significant effects of warm-up exercises were seen from day 2. There was, however, no significant difference (P > 0.05 in the range of movement (ROM scores. Compared with warm-up exercises (Group B, infrared resulted in significantly lower NPRS and DP scores and greater ROM only on day 1. Conclusion: Infrared radiation (IRR is effective in ameliorating the symptoms of DOMS immediately after treatment on day 1 while the effect of warm-up exercises is seen 24 h later. IRR, thus, has

  18. Effect of dissolved organic matter (DOM) of contrasting origins on Cu and Pb speciation and toxicity to Paracentrotus lividus larvae

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez-Marin, Paula, E-mail: paulasanchez@uvigo.es [Laboratorio de Ecoloxia Marina (LEM), Universidade de Vigo, Campus Universitario, 36310 Vigo, Galicia (Spain); Santos-Echeandia, Juan; Nieto-Cid, Mar; Alvarez-Salgado, Xose Anton [Instituto de Investigacions Marinas, Consejo Superior de Investigaciones Cientificas (CSIC), Eduardo Cabello 6, 36208 Vigo, Galicia (Spain); Beiras, Ricardo [Laboratorio de Ecoloxia Marina (LEM), Universidade de Vigo, Campus Universitario, 36310 Vigo, Galicia (Spain)

    2010-01-31

    Water samples of contrasting origin, including natural seawater, two sediment elutriates and sewage-influenced seawater, were collected and obtained to examine the effect of the dissolved organic matter (DOM) present on metal bioavailability. The carbon content (DOC) and the optical properties (absorbance and fluorescence) of the coloured DOM fraction (CDOM) of these materials were determined. Cu and Pb complexation properties were measured by anodic stripping voltammetry (ASV) and the effect of DOM on Cu and Pb bioavailability was studied by means of the Paracentrotus lividus embryo-larval bioassay. Sediment elutriates and sewage-influenced water (1) were enriched 1.4-1.7 times in DOC; (2) absorbed and reemitted more light; and (3) presented higher Cu complexation capacities (L{sub Cu}) than the natural seawater used for their preparation. L{sub Cu} varied from 0.08 {mu}M in natural seawater to 0.3 and 0.5 {mu}M in sediment elutriates and sewage-influenced water, respectively. Differences in DOC, CDOM and Cu complexation capacities were reflected in Cu toxicity. DOM enriched samples presented a Cu EC{sub 50} of 0.64 {mu}M, significantly higher than the Cu EC{sub 50} of natural and artificial seawater, which was 0.38 {mu}M. The protecting effect of DOM on Cu toxicity greatly disappeared when the samples were irradiated with high intensity UV-light. Cu toxicity could be successfully predicted considering ASV-labile Cu concentrations in the samples. Pb complexation by DOM was only detected in the DOM-enriched samples and caused little effect on Pb EC{sub 50}. This effect was contrary for both elutriates: one elutriate reduced Pb toxicity in comparison with the control artificial seawater, while the other increased it. UV irradiation of the samples caused a marked increase in Pb toxicity, which correlated with the remaining DOC concentration. DOM parameters were related to Cu speciation and toxicity: good correlations were found between DOC and Cu EC{sub 50}, while L

  19. Investigating the effect of hardness cations on coagulation: The aspect of neutralisation through Al(III)-dissolved organic matter (DOM) binding.

    Science.gov (United States)

    Zhou, Yuxuan; Yan, Mingquan; Liu, Ruiping; Wang, Dongsheng; Qu, Jiuhui

    2017-05-15

    Hardness cations are ubiquitous and abundant in source water, while the effect of hardness on the performance of coagulation for dissolved organic matter (DOM) removal in water treatment remains unclear due to the limitation of methods that can characterise the subtle interactions between DOM, coagulant and hardness cations. This work quantified the competition between coagulant Al 3+ and hardness cations to bind onto DOM using absorbance spectroscopy acquired at different Al 3+ concentrations in the absence and presence of Ca 2+ or Mg 2+ . The results indicate that, in the presence of either Mg 2+ or Ca 2+ , an increasing depression of the binding of Al 3+ -DOM could be observed in the differential spectra of DOM with the increasing of Mg 2+ or Ca 2+ at a level of 10, 100 and 1000 μM, with the observation being more significant at higher pH from 6.5 to 8.5. The results of zeta potentials of DOM indicate that the competition of hardness cations results in the negative DOM being less efficiently neutralised by Al 3+ . This study demonstrates that the removal of DOM by coagulation would significantly deteriorate with the presence of hardness cations, which would compete with coagulant Al 3+ to neutralise the unsaturated sites in DOM. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. Molecular characterization of phytoplankton dissolved organic matter (DOM) and sulfur components using high resolution Orbitrap mass spectrometry.

    Science.gov (United States)

    Mangal, Vaughn; Stock, Naomi L; Guéguen, Celine

    2016-03-01

    Orbitrap high resolution mass spectrometry (HRMS) with electrospray ionization in both positive and negative polarity was conducted on Suwannee River fulvic acid (SRFA), Pony Lake fulvic acid (PLFA) standards, and dissolved organic matter (DOM) released by freshwater phytoplankton (Scenedesmus obliquus, Euglena mutabilis, and Euglena gracilis). Three-dimensional van Krevelen diagrams expressing various oxygenation states of sulfur molecules and abundance plots of sulfur-containing species were constructed. Orbitrap HRMS analysis of SRFA found a high density of peaks in the lignin region (77 %) and low density of protein material (6.53 %), whereas for PLFA, 25 % of the total peaks were lignin related compared to 56 % of peaks in protein regions, comparable with other HRMS studies. Phytoplankton-derived DOM of S. obliquus, E. mutabilis, and E. gracilis was dominated by protein molecules at respective percentages of 36, 46, and 49 %, and is consistent with previous experiments examining phytoplankton-derived DOM composition. The normalized percentage of SO-containing compounds was determined among the three phytoplankton to be 56 % for Scenedesmus, 54 % for E. mutabilis, and 47 % for E. gracilis, suggesting variation between sulfur content in phytoplankton-derived DOM and differences in metal binding capacities. These results suggest the level of resolution by Orbitrap mass spectrometry is sufficient for preliminary characterization of phytoplankton DOM at an affordable cost relative to other HRMS techniques.

  1. Para uma nova edição crítica de «Dom Casmurro»

    Directory of Open Access Journals (Sweden)

    Manoel Mourivaldo Santiago-Almeida

    2010-12-01

    Full Text Available Resumo: Este texto tem o objetivo de propor uma edição diplomática cotejada e anotada da 2ª edição de Dom Casmurro (1900, última forma da obra dada por Machado de Assis, que faleceu em 1908. A finalidade é preparar material suficiente para uma nova edição crítica do romance.Palavras-chave: Crítica textual; edição crítica; Dom Casmurro; Machado de Assis.Résumé: Ce texte a pour objectif de proposer l’édition diplomatique confronté et annotée de la seconde édition de Dom Casmurro (1900, la dernière version de l’oeuvre écrite par Machado de Assis, décédé en 1908. Le but est de préparer le matériel suffisant pour une nouvelle édition critique du roman.Mots-clés: Critique textuelle; édition critique; Dom Casmurro; Machado de Assis.Keywords: Textual criticism; critical edition; Dom Casmurro; Machado de Assis.

  2. ExDom: an integrated database for comparative analysis of the exon-intron structures of protein domains in eukaryotes.

    Science.gov (United States)

    Bhasi, Ashwini; Philip, Philge; Manikandan, Vinu; Senapathy, Periannan

    2009-01-01

    We have developed ExDom, a unique database for the comparative analysis of the exon-intron structures of 96 680 protein domains from seven eukaryotic organisms (Homo sapiens, Mus musculus, Bos taurus, Rattus norvegicus, Danio rerio, Gallus gallus and Arabidopsis thaliana). ExDom provides integrated access to exon-domain data through a sophisticated web interface which has the following analytical capabilities: (i) intergenomic and intragenomic comparative analysis of exon-intron structure of domains; (ii) color-coded graphical display of the domain architecture of proteins correlated with their corresponding exon-intron structures; (iii) graphical analysis of multiple sequence alignments of amino acid and coding nucleotide sequences of homologous protein domains from seven organisms; (iv) comparative graphical display of exon distributions within the tertiary structures of protein domains; and (v) visualization of exon-intron structures of alternative transcripts of a gene correlated to variations in the domain architecture of corresponding protein isoforms. These novel analytical features are highly suited for detailed investigations on the exon-intron structure of domains and make ExDom a powerful tool for exploring several key questions concerning the function, origin and evolution of genes and proteins. ExDom database is freely accessible at: http://66.170.16.154/ExDom/.

  3. The Defective Nuclear Lamina in Hutchinson-Gilford Progeria Syndrome Disrupts the Nucleocytoplasmic Ran Gradient and Inhibits Nuclear Localization of Ubc9▿

    Science.gov (United States)

    Kelley, Joshua B.; Datta, Sutirtha; Snow, Chelsi J.; Chatterjee, Mandovi; Ni, Li; Spencer, Adam; Yang, Chun-Song; Cubeñas-Potts, Caelin; Matunis, Michael J.; Paschal, Bryce M.

    2011-01-01

    The mutant form of lamin A responsible for the premature aging disease Hutchinson-Gilford progeria syndrome (termed progerin) acts as a dominant negative protein that changes the structure of the nuclear lamina. How the perturbation of the nuclear lamina in progeria is transduced into cellular changes is undefined. Using patient fibroblasts and a variety of cell-based assays, we determined that progerin expression in Hutchinson-Gilford progeria syndrome inhibits the nucleocytoplasmic transport of several factors with key roles in nuclear function. We found that progerin reduces the nuclear/cytoplasmic concentration of the Ran GTPase and inhibits the nuclear localization of Ubc9, the sole E2 for SUMOylation, and of TPR, the nucleoporin that forms the basket on the nuclear side of the nuclear pore complex. Forcing the nuclear localization of Ubc9 in progerin-expressing cells rescues the Ran gradient and TPR import, indicating that these pathways are linked. Reducing nuclear SUMOylation decreases the nuclear mobility of the Ran nucleotide exchange factor RCC1 in vivo, and the addition of SUMO E1 and E2 promotes the dissociation of RCC1 and Ran from chromatin in vitro. Our data suggest that the cellular effects of progerin are transduced, at least in part, through reduced function of the Ran GTPase and SUMOylation pathways. PMID:21670151

  4. RANS simulations of wind turbine wakes: optimal tuning of turbulence closure and aerodynamic loads from LiDAR and SCADA data

    Science.gov (United States)

    Letizia, Stefano; Puccioni, Matteo; Zhan, Lu; Viola, Francesco; Camarri, Simone; Iungo, Giacomo Valerio

    2017-11-01

    Numerical simulations of wakes produced by utility-scale wind turbines still present challenges related to the variability of the atmospheric conditions and, in the most of the cases, the lack of information about the geometry and aerodynamic performance of the wind turbine blades. In order to overcome the mentioned difficulties, we propose a RANS solver for which turbine aerodynamic forcing and turbulence closure are calibrated through LiDAR and SCADA data acquired for an onshore wind farm. The wind farm under examination is located in North Texas over a relatively flat terrain. The experimental data are leveraged to maximize accuracy of the RANS predictions in terms of wake velocity field and power capture for different atmospheric stability conditions and settings of the wind turbines. The optimization of the RANS parameters is performed through an adjoint-RANS formulation and a gradient-based procedure. The optimally-tuned aerodynamic forcing and turbulence closure are then analyzed in order to investigate effects of the atmospheric stability on the evolution of wind turbine wakes and power performance. The proposed RANS solver has low computational costs comparable to those of wake engineering models, which make it a compelling tool for wind farm control and optimization. Acknowledgments: NSF I/UCRC WindSTAR IIP 1362033 and TACC.

  5. A Mobility Management Using Follow-Me Cloud-Cloudlet in Fog-Computing-Based RANs for Smart Cities.

    Science.gov (United States)

    Chen, Yuh-Shyan; Tsai, Yi-Ting

    2018-02-06

    Mobility management for supporting the location tracking and location-based service (LBS) is an important issue of smart city by providing the means for the smooth transportation of people and goods. The mobility is useful to contribute the innovation in both public and private transportation infrastructures for smart cities. With the assistance of edge/fog computing, this paper presents a fully new mobility management using the proposed follow-me cloud-cloudlet (FMCL) approach in fog-computing-based radio access networks (Fog-RANs) for smart cities. The proposed follow-me cloud-cloudlet approach is an integration strategy of follow-me cloud (FMC) and follow-me edge (FME) (or called cloudlet). A user equipment (UE) receives the data, transmitted from original cloud, into the original edge cloud before the handover operation. After the handover operation, an UE searches for a new cloud, called as a migrated cloud, and a new edge cloud, called as a migrated edge cloud near to UE, where the remaining data is migrated from the original cloud to the migrated cloud and all the remaining data are received in the new edge cloud. Existing FMC results do not have the property of the VM migration between cloudlets for the purpose of reducing the transmission latency, and existing FME results do not keep the property of the service migration between data centers for reducing the transmission latency. Our proposed FMCL approach can simultaneously keep the VM migration between cloudlets and service migration between data centers to significantly reduce the transmission latency. The new proposed mobility management using FMCL approach aims to reduce the total transmission time if some data packets are pre-scheduled and pre-stored into the cache of cloudlet if UE is switching from the previous Fog-RAN to the serving Fog-RAN. To illustrate the performance achievement, the mathematical analysis and simulation results are examined in terms of the total transmission time, the

  6. A Mobility Management Using Follow-Me Cloud-Cloudlet in Fog-Computing-Based RANs for Smart Cities

    Directory of Open Access Journals (Sweden)

    Yuh-Shyan Chen

    2018-02-01

    Full Text Available Mobility management for supporting the location tracking and location-based service (LBS is an important issue of smart city by providing the means for the smooth transportation of people and goods. The mobility is useful to contribute the innovation in both public and private transportation infrastructures for smart cities. With the assistance of edge/fog computing, this paper presents a fully new mobility management using the proposed follow-me cloud-cloudlet (FMCL approach in fog-computing-based radio access networks (Fog-RANs for smart cities. The proposed follow-me cloud-cloudlet approach is an integration strategy of follow-me cloud (FMC and follow-me edge (FME (or called cloudlet. A user equipment (UE receives the data, transmitted from original cloud, into the original edge cloud before the handover operation. After the handover operation, an UE searches for a new cloud, called as a migrated cloud, and a new edge cloud, called as a migrated edge cloud near to UE, where the remaining data is migrated from the original cloud to the migrated cloud and all the remaining data are received in the new edge cloud. Existing FMC results do not have the property of the VM migration between cloudlets for the purpose of reducing the transmission latency, and existing FME results do not keep the property of the service migration between data centers for reducing the transmission latency. Our proposed FMCL approach can simultaneously keep the VM migration between cloudlets and service migration between data centers to significantly reduce the transmission latency. The new proposed mobility management using FMCL approach aims to reduce the total transmission time if some data packets are pre-scheduled and pre-stored into the cache of cloudlet if UE is switching from the previous Fog-RAN to the serving Fog-RAN. To illustrate the performance achievement, the mathematical analysis and simulation results are examined in terms of the total transmission time

  7. Tratamiento Híbrido de agua residual gris doméstica

    Directory of Open Access Journals (Sweden)

    Pablo Paredes

    2013-07-01

    Full Text Available El reúso del agua residual gris doméstica es una práctica que también puede aplicarse en nuestro país. Este reúso ayudaria a reducir los costos de consumo de agua potable que actualmente poseen las personas de estratos medio y bajo en el país. Este estudio aplica un concepto nuevo de sistema de tratamiento híbrido para descontaminar el agua y poderla reusar para riego de jardines o para llenar el tanque de los inodoros en una vivienda. Un tratamiento de agua residual gris doméstica híbrido plantea la consecución de remociones totales de materia orgánica, sólidos suspendidos totales, coliformes fecales del 93 %, 92 % y 99,2 %, respectivamente. Este tipo de tratamiento puede tener un valor agregado al disminuir las descargas de aguas servidas a través del sistema de alcantarillado sanitario, con el abaratamiento de la infraestructura para los organismos seccionales del país.

  8. Os domínios da Tecnologia Educacional no campo da Saúde

    Directory of Open Access Journals (Sweden)

    Grasiele Nespoli

    2013-12-01

    Full Text Available Este artigo apresenta os resultados de um estudo que investigou a formação discursiva da Tecnologia Educacional e sua relação com o contexto histórico, político e social da reforma sanitária brasileira, por meio de uma análise do acervo do Núcleo de Tecnologia Educacional para a Saúde da Universidade Federal do Rio de Janeiro. Com base em noções teóricas da arqueologia de Michel Foucault, foram selecionados e analisados documentos que permitem identificar enunciados e avaliar as continuidades e descontinuidades discursivas que marcam a formação de domínios de saber acerca da Tecnologia Educacional. Conclui-se que foram constituídos três domínios de saber - instrução programada, integração ensino-serviço e educação em saúde - que colocam em disputa diferentes enunciados e possibilitam a passagem de uma visão tecnicista para uma visão crítica comprometida com a construção do Sistema Único de Saúde.

  9. Turismo doméstico en Colombia en un contexto de conflicto armado (1996-2001

    Directory of Open Access Journals (Sweden)

    Anne Marie van Broeck

    2002-11-01

    Full Text Available En Colombia las actividades que componen la oferta del turismo, tanto internacional como doméstico, han sido siempre relativamente limitados; se puede considerar el conflicto armado en este país como una causa importante para tal fenómeno. Este ensayo está enfocado al turismo doméstico desde 1996 hasta 2001 y demuestra que aunque el conflicto armado en esos años se ha intensificado, los colombianos han continuado la cultura del viaje aunque sea menos frecuente y de forma distinta.Este ensayo hace parte de una investigación más amplia y de una publicación futura sobre la actitud y el discurso del sector turístico, tanto público como privado, desde los municipios y el gobierno; quienes han continuado la promoción del turismo y han seguido desarrollando colectivamente planes y políticas, regionales y nacionales en un contexto de conflicto armado.

  10. Mujeres del servicio doméstico e intimidad familiar en Bogotá

    Directory of Open Access Journals (Sweden)

    Ana Camila García

    2013-01-01

    Full Text Available Este artículo analiza las prácticas de sujeción y subordinación a las cuales fueron sometidas las mujeres que trabajaban en el sector del servicio doméstico en Bogotá de 1950 a 1980. Primero, presento el enfoque metodológico desde el cual me acerco a la importancia que este oficio ha tenido para muchas familias de clase media en la ciudad de Bogotá. Después, discuto el control que los patrones ejercían sobre el comportamiento y la sexualidad de estas mujeres, que debían mantener su reputación. Finalmente, exploro la sexualización de la figura femenina del servicio doméstico y las contradicciones de una moralidad dual dentro del grupo familiar, en el que se oponían matrimonio a erotismo, y los roles de la señora y la criada.

  11. Freshwater DOM quantity and quality from a two-component model of UV absorbance

    Science.gov (United States)

    Carter, Heather T.; Tipping, Edward; Koprivnjak, Jean-Francois; Miller, Matthew P.; Cookson, Brenda; Hamilton-Taylor, John

    2012-01-01

    We present a model that considers UV-absorbing dissolved organic matter (DOM) to consist of two components (A and B), each with a distinct and constant spectrum. Component A absorbs UV light strongly, and is therefore presumed to possess aromatic chromophores and hydrophobic character, whereas B absorbs weakly and can be assumed hydrophilic. We parameterised the model with dissolved organic carbon concentrations [DOC] and corresponding UV spectra for c. 1700 filtered surface water samples from North America and the United Kingdom, by optimising extinction coefficients for A and B, together with a small constant concentration of non-absorbing DOM (0.80 mg DOC L-1). Good unbiased predictions of [DOC] from absorbance data at 270 and 350 nm were obtained (r2 = 0.98), the sum of squared residuals in [DOC] being reduced by 66% compared to a regression model fitted to absorbance at 270 nm alone. The parameterised model can use measured optical absorbance values at any pair of suitable wavelengths to calculate both [DOC] and the relative amounts of A and B in a water sample, i.e. measures of quantity and quality. Blind prediction of [DOC] was satisfactory for 9 of 11 independent data sets (181 of 213 individual samples).

  12. Sexualidad, embarazo y violencia doméstica: experiencias de adolescentes brasileñas

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    Rosana Santos Mota

    2014-09-01

    Full Text Available Objetivo principal: este estudio tiene como objetivo analizar la sexualidad y la experiencia de adolescentes embarazadas víctimas de violencia doméstica. Metodología: se trata de una investigación cualitativa realizada en el municipio de San Francisco del Conde, en el estado de Bahía, Brasil. La población estudiada estuvo constituida por cinco adolescentes embarazadas, con edad entre 16 y 19 años. El análisis de los datos fue realizado según la analogía de Bardin, resultando en agrupamiento de tres categorías temáticas: la primera relación sexual, el embarazo en la adolescencia y la vivencia de violencia. Resultados principales: el estudio señala la iniciación sexual precoz de las mujeres adolescentes. Destaca la necesidad de contar con políticas de salud eficaces para enfrentar la no adhesión de las adolescentes brasileñas a los métodos anticonceptivos. Conclusión principal: la vivencia de violencia doméstica fue un evento muy significativo en la vida de las adolescentes estudiadas y el patrón de las manifestaciones de violencia fue alterado con la aparición del embarazo.

  13. Dualismo e cosmologia Kaingang: o xamã e o domínio da floresta

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    Sergio Baptista da Silva

    2002-12-01

    Full Text Available Este texto enfoca as interpenetrações entre os diferentes domínios do cosmos Kaingang, discutindo, principalmente, o papel do sistema xamânico como mediador entre esses domínios. Ao mesmo tempo, constitui-se numa tentativa de compreender a construção cultural do conceito de "natureza" da sociedade Kaingang, refletindo sobre sua concepção cosmológica dualista que enfatiza a fertilidade da junção de princípios percebidos como contrários.The present article focuses on the interrelationships between the different domains of the Kaingang cosmos. In particular, this article discusses the role of the shaman system as a mediator between these cosmic domains. The present reflection also attempts to understand how the Kaingang society culturally construes its idea of "nature," based on studies of this societies' dualistic cosmological conception, which emphasizes the fertility of uniting principles held to be in opposition.

  14. Dom Casmurro começou na imprensa por José Dias

    Directory of Open Access Journals (Sweden)

    Letícia Malard

    2000-03-01

    Full Text Available O periódico República de 15/ 11/1896 estampou "Um agregado" (capítulo de um livro inédito - redação primitiva dos capítulos III,IV e V de Dom Casmurro. Ao contrário de outros romances do autor,que foram publicados na íntegra, em periódicos, e sofreram modifica ções,profundas em alguns casos, para publicação em livro, esse é o úni copré-texto do Dom Casmurro, ao que se sabe até agora. Sua importâncianão está tanto no fato do que e do como foi aproveitado nos mencionadoscapítulos, mas naquilo que foi totalmente desca rtado. Umacomparação entre textos e pré-texto tentará revelar: a mudanças de rumoque Machado quis imprimir em sua obra-prima - já iniciada ou atémesmo concluída naquele ano; b traços multiculturais motivadoresdas alterações efetuadas; c reengenharia da língua literária.

  15. Violencia doméstica: hombres versus mujeres maltratantes en la ciudad de Barranquilla

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    Leticia Elena Hundek Pichón

    2010-07-01

    Full Text Available ResumenLas víctimas son hombres a quienes las esposas descalifican, sobre todo si pierden el empleo. Reciben insultos, golpes o rasguños. Dicen que el problema no es nuevo pero recién ahora se ve.Mucho se habló y se habla sobre violencia doméstica. Las mujeres, poco a poco, aprendieron a denunciarmalos tratos por parte de sus maridos. Pero el fenómeno tiene otra cara. A veces las víctimas son ellos. No sin cierta timidez, algunos hombres empiezan a animarse a buscar ayuda cuando se sienten superados por las agresiones- físicas o psicológicas- de sus esposas.Palabras claveDoméstico, Violencia Directa, Maltratantes, Pareja, Golpeados, Chantaje EmocionalAbstractThe victims are men who their wives disallow, above all if they get out of their jobs. We have spoken a lot and often about domestic violence. Women, gradually, learn to report the cruel treatment done by their husbands. But this fact has. Another face. Sometimes, they are the victims. With a little of timidity, some men begin to look for help when they fell bad by the physical or psychological assault of their wives.Key words:Domestic, Violence, Direct, Mistreat, Couple, Beaten, Emotional Blackmail.

  16. Dom casmurro - romance, trágico, romântico ou realista

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    Kathrin H. Rosenfield

    2001-03-01

    Full Text Available Dom Casmurro é freqüentemente apresentado como um romance que desenvolve a temática da infidelidade. Outras abordagens otratam como um romance “trágico”, comparável a Em busca do tempo perdido, porém demunido do consolo metafísico que fornece a obra deProust. Propomos aqui uma leitura que mostra como Machado se inscreve na dissolução das estruturas trágicas, segundo a tradição narrativa de Flaubert e de Maupassant. Em vez de focalizar um “antes” idílico, idade de ouro perdida “depois” da descoberta da suposta infidelidade, procuramos mostrar que o “Mal” machadiano se prepara nas constelações da timidez, da moleza dos sentidos e do espírito. Nessa perspectiva, Dom Casmurro é uma versão moderna da temida acedia melancólica e Machado desenha, com um misto de ironia e de ternura, a fisionomía moderna do vício que Dürer fixou na sua famosa litografia “A Melancolia”. No acanhamento tímido desaparece a transgressão positiva ou passional, e no lugar de uma ação fatal surge a entrega passiva ao que é dado – o gosto indulgente da repetição e o ressentimento.

  17. Dissolved Organic Matter (DOM) From Different Composts: Comparative Study Of Properties And Allelochemical Effects On Horticultural Plants

    Science.gov (United States)

    Traversa, A.; Loffredo, E.; Gattullo, C. E.; Senesi, N.

    2009-04-01

    Dissolved organic matter (DOM) from compost has a major role in numerous chemical and biological processes occurring in the bulk substrate or compost amended soil, and can exert allelochemical effects on plant germination and growth. The objectives of this study were: (i) to investigate comparatively the main properties of three DOM fractions isolated from a green compost (DOMGC), a mixed compost (DOMMC) and a green coffee compost (DOMGCC), and (ii) to evaluate their allelochemical effects on the germination and early growth of two horticultural plants of worldwide interest such as tomato and lettuce. The DOM was extracted from each compost with distilled water (1/10 w/v) under mechanical shaking for 15 min. The suspension was then centrifuged at 6000 rpm for 15 min and filtered sequentially through filters with decreasing particle size retention (from 11 to 0.45 μm). Each DOM sample was characterized by means of pH, electrical conductivity, total organic carbon (TOC), E4/E6 ratio, fluorescence and FT IR spectroscopies and HPLC analysis. Comparative evaluation of the three DOM samples indicated the occurrence of significant differences among them. In particular, the pH value was similar and close to neutrality for DOMMC and DOMGC, whereas it resulted alkaline (pH 8.3) for DOMGCC. The EC values were also similar (about 3.2 mS/cm) for DOMMC and DOMGC and almost half value for DOMGCC. The TOC content, the E4/E6 ratio, the ɛ280 value and the humification index followed the same order: DOMGCC>DOMMC>DOMGC. The fluorescence analysis of the three DOM samples showed the presence of a common fluorophore unit associated to simple aromatic units such as phenolic-like, hydroxy-substituted benzoic and cinnamic acid derivatives. The peak wavelengths observed in the fluorescence emission, excitation and synchronous scan spectra of DOMGCC were generally higher than those of the two other DOM samples, which can be ascribed to a more extended aromatic system of the former. The FT

  18. In vivo FRET imaging revealed a regulatory role of RanGTP in kinetochore-microtubule attachments via Aurora B kinase.

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    Yoke-Peng Lee

    Full Text Available Under the fluctuating circumstances provided by the innate dynamics of microtubules and opposing tensions resulted from microtubule-associated motors, it is vital to ensure stable kinetochore-microtubule attachments for accurate segregation. However, a comprehensive understanding of how this regulation is mechanistically achieved remains elusive. Using our newly designed live cell FRET time-lapse imaging, we found that post-metaphase RanGTP is crucial in the maintenance of stable kinetochore-microtubule attachments by regulating Aurora B kinase via the NES-bearing Mst1. More importantly, our study demonstrates that by ensuring stable alignment of metaphase chromosomes prior to segregation, RanGTP is indispensible in governing the genomic integrity and the fidelity of cell cycle progression. Our findings suggest an additional role of RanGTP beyond its known function in mitotic spindle assembly during the prometaphase-metaphase transition.

  19. The effect of dissolved organic matter (DOM) on sodium transport and nitrogenous waste excretion of the freshwater cladoceran (Daphnia magna) at circumneutral and low pH.

    Science.gov (United States)

    Al-Reasi, Hassan A; Yusuf, Usman; Smith, D Scott; Wood, Chris M

    2013-11-01

    Dissolved organic matter (DOM), a heterogeneous substance found in all natural waters, has many documented abiotic roles, but recently, several possible direct influences of DOM on organism physiology have been reported. However, most studies have been carried out with a limited number of natural DOM isolates or were restricted to the use of commercial or artificial humic substances. We therefore employed three previously characterized, chemically-distinct natural DOMs, as well as a commercially available humic acid (Aldrich, AHA), at circumneutral (7-8) and acidic pH (~5), to examine DOM effects on whole-body Na(+) concentration, unidirectional influx and efflux rates of Na(+), and ammonia and urea excretion rates in Daphnia magna. Whole-body Na(+) concentration, Na(+) influx, and Na(+) efflux rates were all unaffected regardless of pH, suggesting no influence of the various natural DOMs on active uptake and passive diffusion of Na(+) in this organism. Ammonia and urea excretion rates were both increased by low pH. Ammonia excretion rates were reduced at circumneutral pH by the most highly colored, allochthonous DOM, and at low pH by all three natural DOMs, as well as by the commercial AHA. Urea excretion rates were not influenced by the presence of the various DOMs in circumneutral solutions, but were attenuated by the presence of two allochthonous DOM sources (isolated from Bannister Lake and Luther Marsh) at acidic pH. The observed reductions may be attributed partially to the higher buffering capacities of natural DOM sources, as well as their ability to interact with biological membranes as estimated by a new measure calculated from their acid-base titration characteristics, the Proton Binding Index (PBI). © 2013.

  20. [FTIR and 13C NMR Analysis of Dissolved Organic Matter (DOM) in the Treatment Process of Tannery Wastewater].

    Science.gov (United States)

    Fan, Chun-hui; Zhang, Ying-chao; Tang, Ze-heng; Wang, Jia-hong

    2015-05-01

    Nowadays, the wastewater quantity discharged yearly from tannery industry is around 0. 2 billion t in China. The contaminants of tannery wastewater include macromolecular organic matters, such as grease, fur scraps and collagen, and the alkaline wastewater appears to be of high content of salt and COD. The quality of tannery wastewater is monitored strictly among all kinds of industry wastewater. In the treatment process of tannery wastewater, the quality of inlet and outlet water is generally analyzed. In fact, the transformation behavior of contaminants should be additionally checked to optimize the treatment conditions. Dissolved organic matter (DOM) is commonly existed in water-bodies and helpful to understand the physicochemical characteristics, while the related work should be further studied on tannery wastewater. The approaches of elemental analysis, thermal gravimetric analysis (TG), Fourier infrared spectroscopy (FTIR) and 13C nuclear magnetic resonance (13C NMR) were used to reveal the characteristics of DOM in the treatment process of tannery wastewater. The results showed the carbon content of DOM samples increased gradually, atomic ratios of H/C increased firstly and then decreased, indicating the organic matters were decomposed into chain structures firstly, finally forming the component hard to degraded. The pyrolysis process of DOM mainly proceeded in the regions of 110~530 °C (aliphatic compound, protein, etc. ) and 530~800 °C (aromatic ring, single bond of C-C, etc. ). The functional groups of DOM included -OH, -NH2, C=O and so on, and the aromatic substances were detected, shown from FTIR figures, in the later period of the reaction, caused by the metabolism effect of micro-organism. The content of alkoxy-C increased to the maximum in the second biochemical pond, and the minimum content of aromatic-C appeared in the second biochemical pond, suggesting the transformation behavior of carbon functional groups. The investigation on DOM in tannery

  1. Book Review: A History of the Czechoslovak Ocean Shipping Company, 1948–1989: How a Small, Landlocked Country Ran Maritime Business During the Cold War

    DEFF Research Database (Denmark)

    Taudal Poulsen, René

    2016-01-01

    Review of: Lenka Krátká: A History of the Czechoslovak Ocean Shipping Company, 1948–1989: How a Small, Landlocked Country Ran Maritime Business During the Cold War. Stuttgart: Ibidem Verlag, 2015. x + 271 pp., tables, notes, bibliography. ISBN: 978-3-8382-0666-0, £23.90 (pbk).......Review of: Lenka Krátká: A History of the Czechoslovak Ocean Shipping Company, 1948–1989: How a Small, Landlocked Country Ran Maritime Business During the Cold War. Stuttgart: Ibidem Verlag, 2015. x + 271 pp., tables, notes, bibliography. ISBN: 978-3-8382-0666-0, £23.90 (pbk)....

  2. Reduction of DOM fractions and their trihalomethane formation potential in surface river water by in-line coagulation with ceramic membrane filtration.

    Science.gov (United States)

    Rakruam, Pharkphum; Wattanachira, Suraphong

    2014-03-01

    This research was aimed at investigating the reduction of DOM fractions and their trihalomethane formation potential (THMFP) by in-line coagulation with 0.1 μm ceramic membrane filtration. The combination of ceramic membrane filtration with a coagulation process is an alternative technology which can be applied to enhance conventional coagulation processes in the field of water treatment and drinking water production. The Ping River water (high turbidity water) was selected as the raw surface water because it is currently the main raw water source for water supply production in the urban and rural areas of Chiang Mai Province. From the investigation, the results showed that the highest percent reductions of DOC, UV-254, and THMFP (47.6%, 71.0%, and 67.4%, respectively) were achieved from in-line coagulation with ceramic membrane filtration at polyaluminum chloride dosage 40 mg/L. Resin adsorption techniques were employed to characterize the DOM in raw surface water and filtered water. The results showed that the use of a ceramic membrane with in-line coagulation was able to most efficiently reduce the hydrophobic fraction (HPOA) (68.5%), which was then followed by the hydrophilic fraction (HPIA) (49.3%). The greater mass DOC reduction of these two fractions provided the highest THMFP reductions (55.1% and 37.2%, respectively). Furthermore, the in-line coagulation with ceramic membrane filtration was able to reduce the hydrophobic (HPOB) fraction which is characterized by high reactivity toward THM formation. The percent reduction of mass DOC and THMFP of HPOB by in-line coagulation with ceramic membrane filtration was 45.9% and 48.0%, respectively. Copyright © 2014 The Research Centre for Eco-Environmental Sciences, Chinese Academy of Sciences. Published by Elsevier B.V. All rights reserved.

  3. Predicting reactivity of model DOM compounds towards chlorine with mediated electrochemical oxidation.

    Science.gov (United States)

    de Vera, Glen Andrew; Gernjak, Wolfgang; Radjenovic, Jelena

    2017-05-01

    Chlorine demand of a water sample depends on the characteristics of dissolved organic matter (DOM). It is an important parameter for water utilities used to assess oxidant and/or disinfectant consumption of source waters during treatment and distribution. In this study, model compounds namely resorcinol, tannic acid, vanillin, cysteine, tyrosine, and tryptophan were used to represent the reactive moieties of complex DOM mixtures. The reactivity of these compounds was evaluated in terms of Cl2 demand and electron donating capacity (EDC). The EDC was determined by mediated electrochemical oxidation (MEO) which involves the use of 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) as an electron shuttle. The Cl2 demand of readily oxidizable compounds (resorcinol, tannic acid, vanillin, and cysteine) was found to correlate well with EDC (R2 = 0.98). The EDC values (mol e-/mol C) of the model compounds are as follows: 1.18 (cysteine) > 0.77 (resorcinol) > 0.59 (vanillin) > 0.52 (tannic acid) > 0.36 (tryptophan) > 0.19 (tyrosine). To determine the effect of pre-oxidation on EDC, ozone was added (0.1 mol O3/mol C) into each model compound solution. Ozonation caused a general decrease in EDC (10-40%), chlorine demand (10-30%), and UV absorbance (10-40%), except for tyrosine which showed both increased UV275 and EDC. Before and after ozonation, 24 h disinfection byproduct (DBP) formation potential tests (Cl2 residual = 1.5 mg/L) were conducted to evaluate the use of EDC for DBP formation prediction. The results indicate that there was no significant correlation between the EDC of the model compounds and the formation potentials of adsorbable organic chlorine, trichloromethane, and trichloroacetic acid. This suggests that while EDC correlates with Cl2 demand, chlorine consumption may not directly translate to DBP formation because oxidation reactions may dominate over substitution reactions. Overall, this study provides useful insights on the

  4. Export of pre-aged, labile DOM from a central California coastal upwelling system: Insights from D/L amino acids and Δ14C signatures

    Science.gov (United States)

    Walker, B. D.; Shen, Y.; Benner, R. H.; Druffel, E. R. M.

    2014-12-01

    Coastal upwelling zones are among the most productive regions in the world and play a major role in global carbon and nitrogen cycles. Recent research suggests that a substantial fraction of newly fixed organic matter is exported offshore in the form of dissolved organic matter (DOM). However, to date only a few studies have examined DOM composition in the context of production and export from upwelling systems. The ultimate fate and geochemical impact of coastal DOM exported to offshore and mesopelagic ecosystems also remains largely unknown. Between 2007-2009 we conducted a high-resolution biogeochemical time series at the Granite Canyon Marine Pollution Studies Lab in part to evaluate the seasonal production and export of DOM from the Central CA coast. Our previous work demonstrated substantial, albeit disparate, seasonal production of dissolved organic carbon and nitrogen (DOC, DON) - with high DON (and low C:N ratios) produced during upwelling and high DOC produced during summer/fall water column stratification (Walker and McCarthy, 2012). Here we present new total dissolved D/L amino acid (TDAA) and UV-oxidizable DOC radiocarbon (Δ14C) data with the goal of determining the relative sources (heterotrophic vs. autotrophic), bioavailability, microbial processing and 14C-ages of C-rich vs. N-rich DOM exported from this upwelling system. Our results suggest that C-rich DOM produced during water column stratification carries a large microbial signature (i.e. high D/L AA ratios and non-protein AA abundance), whereas N-rich DOM produced during upwelling appears to be fresh, autotrophic DOM (i.e. lowest D/L AA ratios and highest TDAA abundance). DOM Δ14C signatures also did not approximate in situ dissolved inorganic carbon (DIC), and instead were far more negative and highly correlated to water mass density. Together our results indicate a previously unrecognized source of highly labile yet pre-aged DOM potentially impacting offshore and mesopelagic ecosystems.

  5. Preparation and high catalytic performance of Au/3DOM Mn2O3 for the oxidation of carbon monoxide and toluene.

    Science.gov (United States)

    Xie, Shaohua; Dai, Hongxing; Deng, Jiguang; Yang, Huanggen; Han, Wen; Arandiyan, Hamidreza; Guo, Guangsheng

    2014-08-30

    Three-dimensionally ordered macroporous (3DOM) Mn2O3 and its supported gold (xAu/3DOM Mn2O3, x=1.9-7.5wt%) nanocatalysts were prepared using the polymethyl methacrylate-templating and polyvinyl alcohol-protected reduction methods, respectively. The 3DOM Mn2O3 and xAu/3DOM Mn2O3 samples exhibited a surface area of 34-38m(2)/g. The Au nanoparticles (NPs) with a size of 3.0-3.5nm were uniformly dispersed on the skeletons of 3DOM Mn2O3. The 5.8Au/3DOM Mn2O3 sample performed the best, giving the T90% (the temperature required for a conversion of 90%) of -15°C at space velocity (SV)=20,000mL/(gh) for CO oxidation and 244°C at SV=40,000mL/(gh) for toluene oxidation. The apparent activation energies (30 and 54kJ/mol) over 5.8Au/3DOM Mn2O3 were much lower than those (80 and 95kJ/mol) over 3DOM Mn2O3 for CO and toluene oxidation, respectively. The effects of SV, water vapor, CO2, and SO2 on catalytic activity were also examined. It is concluded that the excellent catalytic performance of 5.8Au/3DOM Mn2O3 was associated with its high oxygen adspecies concentration, good low-temperature reducibility, and strong interaction between Au NPs and 3DOM Mn2O3 as well as high-quality porous architecture. Copyright © 2014 Elsevier B.V. All rights reserved.

  6. Género, trabajo doméstico y extradoméstico en México. Una estimación del valor económico del trabajo doméstico

    Directory of Open Access Journals (Sweden)

    Mercedes Pedrero Nieto

    2004-01-01

    Full Text Available La discusión sobre la importancia del trabajo doméstico no remunerado tiene ya varios decenios, así como sus efectos sobre la participación en el trabajo extradoméstico, particularmente porque frena a las mujeres para realizar actividades destinadas al mercado. Sin embargo, fue apenas en la última década cuando en el contexto internacional comenzaron a realizarse esfuerzos sistemáticos para hacer visible y medir el trabajo doméstico y registrarlo en las estadísticas oficiales. Las fronteras entre lo que se considera doméstico y extradoméstico no han sido estáticas, lo cual obliga a hacer una revisión conceptual permanente y a diseñar metodologías que permitan cuantificar la valoración económica del trabajo doméstico. En este artículo se emprende, primero, un recorrido conceptual, para finalizar con la presentación de algunos resultados obtenidos para México por la Encuesta Nacional sobre Uso del Tiempo de 2002. Se muestra la participación diferencial de hombres y mujeres en los dos tipos de trabajo, y se destaca sobre todo las discrepancias en el tiempo dedicado al trabajo doméstico por los hombres y por las mujeres. Finalmente se presenta un ejercicio de medición para demostrar que no se trata de una contribución marginal, pues su valor supera al de varios sectores económicos.

  7. Apprehending Dom Casmurro through Criticism Posed to Novel and Television Micro-Series

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    Alexandre de Assis Monteiro

    2016-09-01

    Full Text Available This paper aims to identify modalities of dialogue between the television series Capitu by Luis Fernando Carvalho and the novel Dom Casmurro by Machado de Assis. It is based on the theory of narratology, mainly on Gerard Genette's contributions. In order to consolidate the study on the nature of narratives, we propose that the texts be read based on the available scrutiny of the two pieces. Moreover, we intend to apprehend the meanings of image and time related to the television show, the process of adaptation, and the modern artistic movements that are found in the process of transmutation of the narrative from a support based on verbal code to a support based on audio-visual-verbal code.

  8. Exploring pluralism in oral health care: Dom informal dentists in northern Lebanon.

    Science.gov (United States)

    Bochi, Giovanni

    2015-03-01

    This article describes a pluralistic regime of oral health provision in a rural part of northern Lebanon, where dental care came from two main sources: professionally trained dentists and "informal" Dom dentists with Syrian nationality. Relying on a combination of interviews and ethnography, I offer a multivocal view of oral health services that incorporates data from patients and formal and informal providers. I argue that informal dentistry constituted an interstitial and translocal mode of dental care. In the northern Lebanese Biqa Valley, close to the Syrian border, the local articulation of neoliberal health governance created opportunities for heterodox practices in oral health. The organization of informality was predicated on the presence of the open border between Syria and Lebanon, which favored patterns of flexible cross-border mobility. In this context, informal dentistry was not alternative, but supplementary and lateral in relation to official forms of oral health provision. © 2014 by the American Anthropological Association.

  9. Mujeres de Guadalajara y violencia doméstica: resultados de un estudio piloto

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    Ramírez Rodríguez Juan Carlos

    1996-01-01

    Full Text Available La violencia doméstica contra la mujer es un problema médico social que continúa soslayado por las instituciones, no sólo de salud, sino en general por la sociedad mexicana. Existen incipientes investigaciones que muestran la magnitud de este fenómeno. Se realizó una encuesta piloto en 57 mujeres de Guadalajara, México, seleccionadas mediante un muestreo polietápico. Se encontró que el 46% de las mujeres habían sufrido de violencia. El perpetrador más frecuente fue el compañero/esposo (73%. De las mujeres que han sufrido de violencia por parte del esposo, la violencia emocional se identificó en el 33%, la violencia física con 19% y la sexual con 12%.

  10. Cultivo de mudas de eucalipto irrigadas com esgoto doméstico tratado

    OpenAIRE

    Robson José Silva; Savia Gavazza; Lourdinha Florencio; Clístenes Williams Araujo Nascimento; Mario Takayuki Kato

    2015-01-01

    Avaliou-se o cultivo de mudas de eucalipto da espécie urograndisirrigadas com esgoto doméstico tratado em estação com reator anaeróbio e lagoa de polimento. A irrigação das mudas, em vaso e com base na capacidade de pote (CP) para o solo, foi efetuada em experimento com seis tratamentos (T), com quatro repetições cada. Em T1, T2, T3 e T4, a irrigação com esgoto foi com lâmina a 100, 80, 60 e 40% do índice CP, respectivamente; em T5 e T6, a irrigação foi com água a 80% de CP. Apenas T5 teve ad...

  11. Rasgos del temperamento de los perros domésticos (Canis familiaris: evaluaciones conductuales

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    ADRIANA JAKOVCEVIC

    2009-01-01

    Full Text Available Los rasgos del temperamento se definen como tendencias conductuales estables entre situaciones similares y a lo largo del tiempo. En el presente trabajo se revisan las pruebas conductuales diseñadas para la evaluación de rasgos aislados del temperamento en los perros domésticos. Para cada dimensión se describen los estímulos empleados, las respuestas evaluadas y el correlato psiológico de las mismas. Los rasgos más estudiados fueron la temerosidad, la agresividad y la sociabilidad. Sin embargo, sólo la primera cuenta con correlatos psiológicos bien establecidos. Finalmente, las evaluaciones conductuales resultan de suma importancia para la selección de los perros para las distintas funciones que cumplen en la sociedad humana: detección de drogas, compañía, guardia, rescate de personas, etc.

  12. Trabalho doméstico e Bem Viver: um desafio para narrativas de publicidade

    Directory of Open Access Journals (Sweden)

    Mariángeles Camusso

    2017-04-01

    Full Text Available As noções de estereótipo, sexismo e violência simbólica não são apenas categorizações habituais em trabalhos de análise de anúncios e campanhas, mas graças ao esforço militante de muitas organizações e iniciativas pedagógicas, elas começaram a fazer parte da doxa mediática e da linguagem cotidiana. Neste trabalho, pretende-se dar conta das observações realizadas nos quase dez anos de existência do Observatório Publicitário sobre Sexismo do Bacharelado em Publicidade da UAI Universidad Abierta Interamericana, atendendo as constantes transformações em torno da representação do trabalho doméstico.

  13. Mujeres de Guadalajara y violencia doméstica: resultados de un estudio piloto

    Directory of Open Access Journals (Sweden)

    Juan Carlos Ramírez Rodríguez

    1996-09-01

    Full Text Available La violencia doméstica contra la mujer es un problema médico social que continúa soslayado por las instituciones, no sólo de salud, sino en general por la sociedad mexicana. Existen incipientes investigaciones que muestran la magnitud de este fenómeno. Se realizó una encuesta piloto en 57 mujeres de Guadalajara, México, seleccionadas mediante un muestreo polietápico. Se encontró que el 46% de las mujeres habían sufrido de violencia. El perpetrador más frecuente fue el compañero/esposo (73%. De las mujeres que han sufrido de violencia por parte del esposo, la violencia emocional se identificó en el 33%, la violencia física con 19% y la sexual con 12%.

  14. [The qualitative analysis method of the dissolved organic matter (DOM) for ABS wastewater].

    Science.gov (United States)

    Lai, Bo; Zhou, Yue-xi; Song, Yu-dong; Xi, Hong-bo; Sun, Li-dong; Chen, Jia-yun

    2011-03-01

    The dissolved organic matter (DOM) of acrylonitrile-butadiene-styrene (ABS) resin wastewater was qualitatively analysed by gas chromatography with mass spectrometry(GC-MS), Fourier transform infrared spectrometer(FTIR) and three-dimensional excitation-emission matrix (EEM) fluorescence spectroscopy. The detected results shows that the GC-MS qualitatively analysed 21 dissolved organic pollutants, such as acetophenone, styrene, alpha, alpha-dimethyl-benzenemethanol, 3,3'oxybis-propanenitrile, 3, 3'-iminobis-propanenitrile, 3,3'-thiobis-propanenitrile, 3-(dimethylamino)-propanenitrile and 2-propenenitrile. The results of Fourier transform infrared spectrometer (FTIR) and three-dimensional excitation-emission matrix (EEM) fluorescence spectroscopy could examine and certify the accuracy and integrity for the qualitative analysis of GC-MS. The results of this study provides an important guiding role for the development of wastewater treatment process.

  15. Hypertension and breast cancer risk in a 19-year foIlow-up study (the DOM cohort)

    NARCIS (Netherlands)

    Peeters, PHM; van Noord, PAH; Hoes, AW; Fracheboud, J; Gimbrere, CHF; Grobbee, DE

    Background To investigate whether hypertension and the use of anti-hypertensive drugs are associated with breast cancer risk. Methods This was a prospective study of 11 011 women living in Utrecht, the Netherlands, aged 50-65 years at enrolment in a breast cancer screening project (DOM cohort).

  16. Fiktioner- Sø- og Handelsrettens dom af 8. november 2011 om køb af kopivarer til privat brug

    DEFF Research Database (Denmark)

    Petersen, Clement Salung; Riis, Thomas; Schovsbo, Jens Hemmingsen

    2012-01-01

    I artiklen diskuteres Sø- og Handelsrettens dom af 8. november 2011, som fastslår, at et Rolex-kopiur, som en dansk forbruger havde forsøgt at importere fra Hongkong, var blevet retmæssigt tilbageholdt af SKAT og skulle afstås til statskassen uden erstatning, selv om importen ikke udgjorde en...

  17. Organic Fe speciation in the Eurasian Basins of the Arctic Ocean and its relation to terrestrial DOM

    DEFF Research Database (Denmark)

    Slagter, H. A.; Reader, H. E.; Rijkenberg, M. J.A.

    2017-01-01

    are subject to rapid changes in the catchments of the main contributing rivers. Here we report concentrations and binding strengths of Fe-binding organic ligands in relation to spectral properties of Dissolved Organic Matter (DOM) and concentrations of humic substances. Full-depth profiles of Fe and Fe...

  18. Diseño de una instalación domótica con tecnología LONWORKS

    OpenAIRE

    Guerrero Meseguer, José Antonio

    2010-01-01

    Utilizando la tecnología LONWORKS, diseñar, optimizar, implementar y probar una red domótica para una vivienda unifamiliar. Todos los equipos Hardware serán instalados en un panel para que facilite la visualización y manejo de los mismos. Escuela Técnica Superior de Ingeniería Industrial

  19. Obesity and fat distribution in relation to hot flashes in Dutch women from the DOM-project

    NARCIS (Netherlands)

    den Tonkelaar, I.; Seidell, J C; van Noord, P.A.H.

    The authors studied obesity and fat distribution in relation to the occurrence of hot flashes in a population-based study comprising 2904 women aged 40-44 and 569 women aged 54-69 presenting for mammographic screening (the DOM-project). Women aged 40-44 in the upper tertiles of Quetelet's index and

  20. The relationship between fat distribution and some chronic diseases in 11,825 women participating in the DOM-project

    NARCIS (Netherlands)

    van Noord, P.A.H.; Seidell, J C; den Tonkelaar, I.; Baanders-van Halewijn, E A; Ouwehand, I J

    The prevalence of reported chronic diseases was studied in quintiles of waist/hip ratio and Quetelet index in 11,825 women aged 40-73 presenting for mammographic screening in the DOM-project. After adjustment for age and Quetelet index, increased waist/hip ratio was found to be associated with an

  1. Obesity and subcutaneous fat patterning in relation to survival of postmenopausal breast cancer patients participating in the DOM-project

    NARCIS (Netherlands)

    den Tonkelaar, I.; de Waard van de Spek, FB; Seidell, J C; Fracheboud, J

    1995-01-01

    The effect of obesity and fat distribution on survival of breast cancer patients was studied prospectively in 241 women with a natural menopause who participated in a breast cancer screening project, the DOM-project in Utrecht, The Netherlands. Mean follow-up time was 9.1 years and endpoint of

  2. Components of adult height and height loss. Secular trend and effects of aging in women in the DOM project

    NARCIS (Netherlands)

    van Leer, E M; van Noord, P.A.H.; Seidell, J C

    Between 1984 and 1987, adult height, sitting height, arm span, and iliac crest height were measured in 13,386 women of the DOM project. Combined effects of secular trends between cohorts born in 1911 to 1945 and aging between ages 40 to 74 years showed a decrease in stature of 4.9 +/- 0.3 cm (mean

  3. HYDROXYL RADICAL/OZONE RATIOS DURING OZONATION PROCESSES. II. THE EFFECT OF TEMPERATURE, PH, ALKALINITY, AND DOM PROPERTIES

    Science.gov (United States)

    The influence of temperature, pH, alkalinity, and type and concentration of the dissolved organic matter (DOM) on the rate of ozone (O3) decomposition, O3-exposure, .OH-exposure and the ratio Rct of the concentrations of .OH and O3 has been studied. For a standardized single ozon...

  4. RanBP9 overexpression accelerates loss of pre and postsynaptic proteins in the APΔE9 transgenic mouse brain.

    Science.gov (United States)

    Wang, Hongjie; Wang, Ruizhi; Xu, Shaohua; Lakshmana, Madepalli K

    2014-01-01

    There is now compelling evidence that the neurodegenerative process in Alzheimer's disease (AD) begins in synapses. Loss of synaptic proteins and functional synapses in the amyloid precursor protein (APP) transgenic mouse models of AD is well established. However, what is the earliest age at which such loss of synapses occurs, and whether known markers of AD progression accelerate functional deficits is completely unknown. We previously showed that RanBP9 overexpression leads to robustly increased amyloid β peptide (Aβ) generation leading to enhanced amyloid plaque burden in a mouse model of AD. In this study we compared synaptic protein levels among four genotypes of mice, i.e., RanBP9 single transgenic (Ran), APΔE9 double transgenic (Dbl), APΔE9/RanBP9 triple transgenic (Tpl) and wild-type (WT) controls. We found significant reductions in the levels of synaptic proteins in both cortex and hippocampus of 5- and 6-months-old but not 3- or 4-months-old mice. Specifically, at 5-months of age, rab3A was reduced in the triple transgenic mice only in the cortex by 25% (pproteins in the mouse brain.

  5. Study of laminar separation bubble on low Reynolds number operating airfoils: RANS modelling by means of an high-accuracy solver and experimental verification

    Science.gov (United States)

    Crivellini, A.; D'Alessandro, V.; Di Benedetto, D.; Montelpare, S.; Ricci, R.

    2014-04-01

    This work is devoted to the Computational Fluid-Dynamics (CFD) simulation of laminar separation bubble (LSB) on low Reynolds number operating airfoils. This phenomenon is of large interest in several fields, such as wind energy, and it is characterised by slow recirculating flow at an almost constant pressure. Presently Reynolds Averaged Navier-Stokes (RANS) methods, due to their limited computational requests, are the more efficient and feasible CFD simulation tool for complex engineering applications involving LSBs. However adopting RANS methods for LSB prediction is very challenging since widely used models assume a fully turbulent regime. For this reason several transitional models for RANS equations based on further Partial Differential Equations (PDE) have been recently introduced in literature. Nevertheless in some cases they show questionable results. In this work RANS equations and the standard Spalart-Allmaras (SA) turbulence model are used to deal with LSB problems obtaining promising results. This innovative result is related to: (i) a particular behaviour of the SA equation; (ii) a particular implementation of SA equation; (iii) the use of a high-order discontinuous Galerkin (DG) solver. The effectiveness of the proposed approach is tested on different airfoils at several angles of attack and Reynolds numbers. Numerical results were verified with both experimental measurements performed at the open circuit subsonic wind tunnel of Università Politecnica delle Marche (UNIVPM) and literature data.

  6. Ozsvath, Zsuzsanna: "When the Danube Ran Red"; Mandel, Eva Marika: "Le Livre de Mana"; Roth, Marika: "All the Pretty Shoes; A Memoir of Survival and the Feminine Spirit".

    Directory of Open Access Journals (Sweden)

    Evi Blaikie

    2011-01-01

    Full Text Available Ozsvath, Zsuzsanna. When the Danube Ran Red. Syracuse University Press, 2010,171 pp., Illus.Mandel, Eva Marika. Le Livre de Mana. Paris, Glyphe 2009, 231 pp., Illus.Roth, Marika. All the Pretty Shoes; A Memoir of Survival and the Feminine SpiritWyatt McKenzy 2010, 254 pp., Illus.Reviewed by Evi Blaikie, Freelance Writer.

  7. Americanismo y criollismo en la Cornucopia de Hernando Domínguez Camargo

    Directory of Open Access Journals (Sweden)

    Kathryn Mayers

    2005-12-01

    Full Text Available This work studies the literary topos of the Cornucopia in a Colombian national patrimony monument - the Heroic Poem to San Ignacio de Loyola from the Jesuit Creole Hernando Domínguez Camargo - This epic-hagiographic poem display a few death natures of natural abundance that shows a veiled reference to the marginalized ethnic groups that composed the colonial society. This study identifies the specific Creole character of this representation, showing that these scenes celebrate on the one hand the pre-Columbian native and by the other deny the rights and powers of their descendents in the seventieth century, which offers a cultural synthesis model that, prefigure certain discrimination politics that still continues today in Colombia.//Este trabajo examina el topos literario de la Cornucopia en un monumento del patrimonio nacional de Colombia — el Poema Heroico a San Ignacio de Loyola del jesuita criollo Hernando Domínguez Camargo —. Este poema épico-hagiográfico despliega una serie de naturalezas muertas de abundancia natural que hacen referencia velada a grupos étnicos marginados que componían la sociedad colonial. El presente estudio identifica el carácter específicamente criollo de esta representación, mostrando que estas escenas celebran al indígena precolombino a la ver que niegan los derechos y poderes de sus descendientes en el siglo XVII lo cual ofrece un modelo de síntesis cultural que prefigura cierta política de discriminación que continúa en Colombia hoy en día.

  8. Atividade reflexiva com mulheres que sofreram violência doméstica

    Directory of Open Access Journals (Sweden)

    Maria Eduarda Ramos

    Full Text Available Este trabalho está baseado em uma atividade reflexiva de grupo com mulheres que sofreram violência doméstica. Esse grupo teve como objetivos: promover discussões que propiciassem a reflexão das mulheres sobre novas formas de enfrentamento das situações de violência ou das consequências desta e formar uma rede social de apoio às mulheres e oportunizar vivências de interação entre as participantes para gerar aprendizagem, desenvolvendo mudanças na sua realidade social. Para isso, foram utilizadas reflexões de ensino-aprendizagem baseadas nas teorias de Paulo Freire, nas quais todos(as ensinam e aprendem. O grupo proporcionou a aprendizagem de novas formas de agir e pensar por meio da interação entre suas participantes. As mudanças foram percebidas através dos relatos sobre a forma pela qual conseguiam buscar seus direitos de igualdade de gênero, ou ainda, como estavam agindo, não se submetendo às agressões físicas e psicológicas de seus companheiros, repensando suas atitudes em relação a eles. Identificou-se, por meio deste trabalho, que, quanto mais agentes multiplicadores se mobilizarem para fazer algo, mais se promove uma sociedade que reflita sobre os papéis estabelecidos para mulheres e homens, sobre a desigualdade de gênero, os direitos humanos e a violência doméstica.

  9. Prevalencia de violencia doméstica en la ciudad de Durango

    Directory of Open Access Journals (Sweden)

    Alvarado-Zaldívar Gloria

    1998-01-01

    Full Text Available Objetivo. Caracterizar y determinar, desde un enfoque de género, la prevalencia de los diferentes tipos de violencia que se presentan en la ciudad de Durango, Dgo., México. Material y métodos. Con un diseño transversal se entrevistaron 384 mujeres casadas, o bien, unidas al momento del estudio o alguna vez, residentes de la ciudad de Durango. El tamaño de la muestra se distribuyó en forma proporcional en seis sectores de la ciudad, seleccionados al azar y representativos de los niveles socioeconómicos alto, medio y bajo. En cada sector se realizaron 64 entrevistas. El instrumento de medición fue un cuestionario con 184 preguntas cerradas y 22 abiertas, que incluía datos de identificación, sociodemográficos y reproductivos, así como reactivos específicos para la violencia física, emocional y sexual. Resultados. La mediana de edad del grupo estudiado fue de 41.5 años, con un rango de 12 a 48 años. La prevalencia de violencia doméstica fue: alguna forma de violencia sexual, 42%; física, 40%, y emocional, 39%. Conclusiones. Se reconoce que el problema de la violencia, en sus diferentes formas, es un hecho altamente prevalente que pone en peligro el bienestar del núcleo familiar. Se observó una mayor prevalencia de violencia doméstica en presencia de factores tales como: antecedente de violencia, alcoholismo y/o consumo de drogas en algún miembro de la familia.

  10. Effects of alfa-hydroxy-isocaproic acid on body composition, DOMS and performance in athletes

    Directory of Open Access Journals (Sweden)

    Karila Tuomo AM

    2010-01-01

    Full Text Available Abstract Background Alfa-Hydroxy-isocaproic acid (HICA is an end product of leucine metabolism in human tissues such as muscle and connective tissue. According to the clinical and experimental studies, HICA can be considered as an anti-catabolic substance. The present study investigated the effects of HICA supplementation on body composition, delayed onset of muscle soreness (DOMS and physical performance of athletes during a training period. Methods Fifteen healthy male soccer players (age 22.1+/-3.9 yr volunteered for the 4-week double-blind study during an intensive training period. The subjects in the group HICA (n = 8 received 583 mg of sodium salt of HICA (corresponding 500 mg of HICA mixed with liquid three times a day for 4 weeks, and those in the group PLACEBO (n = 7 received 650 mg of maltodextrin mixed with liquid three times a day for the same period. According to a weekly training schedule, they practiced soccer 3 - 4 times a week, had strength training 1 - 2 times a week, and had one soccer game during the study. The subjects were required to keep diaries on training, nutrition, and symptoms of DOMS. Body composition was evaluated with a dual-energy X-ray absorptiometry (DXA before and after the 4-week period. Muscle strength and running velocity were measured with field tests. Results As compared to placebo, the HICA supplementation increased significantly body weight (p th week of the treatment (p Conclusion Already a 4-week HICA supplementation of 1.5 g a day leads to small increases in muscle mass during an intensive training period in soccer athletes.

  11. Importancia médica de los alergenos de ácaros domésticos

    Directory of Open Access Journals (Sweden)

    Liliana Moreno

    1995-06-01

    Full Text Available En la actualidad, los trastornos respiratorios están entre los problemas de salud más frecuentes y, entre ellos, el asma aparece como una entidad muy común en niños y adultos. El asma alérgica es una enfermedad multifactorial. El componente ambiental es de gran importancia, lo cual ha sido ampliamente documentado gracias a los avances científicos que en los últimos años se han dado en el campo de la alergología experimental. Los ácaros domésticos son la principal fuente de alergenos en el polvo casero; dichos alergenos son considerados, hoy en día, como los principales inductores de las manifestaciones alérgicas respiratorias. Estos animales son artrópodos de distribución mundial, siendo Dermatophagoides pteronyssinus y Blomia tropicalis los que más frecuentemente se encuentran en el ambiente doméstico. Las mencionadas especies ejercen un gran impacto clínico porque la mayoría de la población asmática y rinítica presenta altos niveles de IgE contra sus alergenos lo cual, sin duda, influye en la patogénesis de la inflamación crónica que caracteriza a esas enfermedades. La presente revisión describe la biología, epidemiología y aspectos moleculares de los alergenos de Dermatophagoides pteronyssinus y Blomia tropicalis, como una información muy útil para los médicos y demás integrantes del equipo de salud que tengan el interés y la oportunidad de efectuar un manejo integral de estos problemas.

  12. A lentiviral sponge for miR-101 regulates RanBP9 expression and amyloid precursor protein metabolism in hippocampal neurons

    Directory of Open Access Journals (Sweden)

    Christian eBarbato

    2014-02-01

    Full Text Available Neurodegeneration associated with amyloid β (Aβ peptide accumulation, synaptic loss, and memory impairment are pathophysiological features of Alzheimer's disease (AD. Numerous microRNAs regulate amyloid precursor protein (APP expression and metabolism. We previously reported that miR-101 is a negative regulator of APP expression in cultured hippocampal neurons. In this study, a search for predicted APP metabolism-associated miR-101 targets led to the identification of a conserved miR-101 binding site within the 3’ untranslated region (UTR of the mRNA encoding Ran-binding protein 9 (RanBP9. RanBP9 increases APP processing by β-amyloid converting enzyme 1 (BACE1, secretion of soluble APPβ (sAPPβ, and generation of Aβ. MiR-101 significantly reduced reporter gene expression when co-transfected with a RanBP9 3'-UTR reporter construct, while site-directed mutagenesis of the predicted miR-101 target site eliminated the reporter response. To investigate the effect of stable inhibition of miR-101 both in vitro and in vivo, a microRNA sponge was developed to bind miR-101 and derepress its targets. Four tandem bulged miR-101 responsive elements (REs, located downstream of the enhanced green fluorescence protein (EGFP open reading frame and driven by the synapsin promoter, were placed in a lentiviral vector to create the pLSyn-miR-101 sponge. Delivery of the sponge to primary hippocampal neurons significantly increased both APP and RanBP9 expression, as well as sAPPβ levels in the conditioned medium. Importantly, silencing of endogenous RanBP9 reduced sAPPβ levels in miR-101 sponge-containing hippocampal cultures, indicating that miR-101 inhibition may increase amyloidogenic processing of APP by RanBP9. Lastly, the impact of miR-101 on its targets was demonstrated in vivo by intrahippocampal injection of the pLSyn-miR-101 sponge into C57BL6 mice. This study thus provides the basis for studying the consequences of long-term miR-101 inhibition on

  13. Comprehensive Approaches to Multiphase Flows in Geophysics - Application to nonisothermal, nonhomogenous, unsteady, large-scale, turbulent dusty clouds I. Hydrodynamic and Thermodynamic RANS and LES Models

    Energy Technology Data Exchange (ETDEWEB)

    S. Dartevelle

    2005-09-05

    The objective of this manuscript is to fully derive a geophysical multiphase model able to ''accommodate'' different multiphase turbulence approaches; viz., the Reynolds Averaged Navier-Stokes (RANS), the Large Eddy Simulation (LES), or hybrid RANSLES. This manuscript is the first part of a larger geophysical multiphase project--lead by LANL--that aims to develop comprehensive modeling tools for large-scale, atmospheric, transient-buoyancy dusty jets and plume (e.g., plinian clouds, nuclear ''mushrooms'', ''supercell'' forest fire plumes) and for boundary-dominated geophysical multiphase gravity currents (e.g., dusty surges, diluted pyroclastic flows, dusty gravity currents in street canyons). LES is a partially deterministic approach constructed on either a spatial- or a temporal-separation between the large and small scales of the flow, whereas RANS is an entirely probabilistic approach constructed on a statistical separation between an ensemble-averaged mean and higher-order statistical moments (the so-called ''fluctuating parts''). Within this specific multiphase context, both turbulence approaches are built up upon the same phasic binary-valued ''function of presence''. This function of presence formally describes the occurrence--or not--of any phase at a given position and time and, therefore, allows to derive the same basic multiphase Navier-Stokes model for either the RANS or the LES frameworks. The only differences between these turbulence frameworks are the closures for the various ''turbulence'' terms involving the unknown variables from the fluctuating (RANS) or from the subgrid (LES) parts. Even though the hydrodynamic and thermodynamic models for RANS and LES have the same set of Partial Differential Equations, the physical interpretations of these PDEs cannot be the same, i.e., RANS models an averaged field, while LES simulates a

  14. from the Kruger National Park, South Africa

    African Journals Online (AJOL)

    DRFTMUSL utilises the population size, mutation rate and selection coefficients as parameters to simulate the combined effect of ran- dom genetic drift, mutation and natural selection. The selection coefficients as well as the initial allele frequencies of the B-allele are specified in SELECTIN. Selection coefficients (a) were ...

  15. Investigation of Synthetic Jets Efficiency to Control Cavity Flotation with Subsonic External Flow by High-Resolution RANS / ILES Method

    Directory of Open Access Journals (Sweden)

    D. A. Lyubimov

    2015-01-01

    Full Text Available Cavities often found in airplanes: a niche for the landing gear, various weapons, etc. Reducing fluctuations of pressure and temperature in the cavity is a relevant practical problem. The article presents simulation results of external subsonic flow around the cavity (M = 0.85, T = 300K. . Calculations were performed using the high-resolution RANS/ILES (Reynolds Averaged Navier-Stokes - RANS, Implicit Large Eddy Simulation - ILES method. To control flow the authors propose to use synthetic jets. Synthetic jets are produced by periodic ejection and suction of fluid from a slot induced by the movement of a diaphragm (generator of synthetic jets inside a cavity. They are compact and efficient and do not require a special working body and the ways for its supply. Instead of calculating the flow in the synthetic jet generator was used the modified boundary condition on the wall where the output slots was positioned. Under consideration there were two variants of slots for synthetic jets output: in front of the cavity and inside the cavity on the front wall. The frequency and amplitude values of the synthetic jet specified a mode of each jet. For a jet inside the cavity two modes have been reviewed, namely: 100 Hz and 50m/s, 200Hz and 50m/s. For jet in front of the cavity three modes have been reviewed, specifically: 20Hz and 20m/s, 100Hz and 50m/s, 200Hz and 50m/s. Analysis of calculation results showed that for all modes under examination, the synthetic jets reduced fluctuation of static pressure and temperature on the bottom and back walls of the cavity. The mode with parameters 200Hz, 50 m/s and synthetic jet located in front of the cavity was the most efficient. Furthermore, we compared the results of calculations for two-and three-dimensional cavities, which have the same length and depth. Research has shown that the simplified quasi-two-dimensional calculations cannot be used to evaluate the pressure and temperature fluctuations. This is due to

  16. The communities of harvestmen (Opilionida of floodplain forest in the Ranšpurk National Nature Reserve and their fluctuations

    Directory of Open Access Journals (Sweden)

    Hana Šejnohová

    2005-01-01

    Full Text Available During the years 1993–2001 the monitoring of the soil surface fauna was carried out in a floodplain fo- rest in the Ranšpurk National Nature Reserve (south Moravia. The harvestmen assemblages fluctuation is described in detail in this paper. The method of pitfall traps was used. A total of 3174 individuals of seven harvestmen species were collected. The species composition was very similar to other research results from the southern Moravian floodplain forest. Only the dominance values differ from the values in the other localities. All of the registered species prefer moisture and shadow places. The highest abundance was observed in Astrobunus laevipes (Canestrini, 1872, Nemastoma lugubre (Müller, 1776, Oligolophus tridens (C. L. Koch, 1936 and Rilaena triangularis (Herbst, 1799. The dynamics of harvestmen occurrence during the year had a different development than in other groups of invertebrates. Harvestmen mostly occurred in pitfall traps in autumn and winter months. The highest abundance of harvestmen in traps was observed in December and January. In July 1997, disastrous flood affected all groups of invertebrates. The flood had a minimal impact on the abundance of harvestmen in pitfall traps.

  17. Proactive monitoring of an onshore wind farm through lidar measurements, SCADA data and a data-driven RANS solver

    Science.gov (United States)

    Iungo, Giacomo Valerio; Camarri, Simone; Ciri, Umberto; El-Asha, Said; Leonardi, Stefano; Rotea, Mario A.; Santhanagopalan, Vignesh; Viola, Francesco; Zhan, Lu

    2016-11-01

    Site conditions, such as topography and local climate, as well as wind farm layout strongly affect performance of a wind power plant. Therefore, predictions of wake interactions and their effects on power production still remain a great challenge in wind energy. For this study, an onshore wind turbine array was monitored through lidar measurements, SCADA and met-tower data. Power losses due to wake interactions were estimated to be approximately 4% and 2% of the total power production under stable and convective conditions, respectively. This dataset was then leveraged for the calibration of a data driven RANS (DDRANS) solver, which is a compelling tool for prediction of wind turbine wakes and power production. DDRANS is characterized by a computational cost as low as that for engineering wake models, and adequate accuracy achieved through data-driven tuning of the turbulence closure model. DDRANS is based on a parabolic formulation, axisymmetry and boundary layer approximations, which allow achieving low computational costs. The turbulence closure model consists in a mixing length model, which is optimally calibrated with the experimental dataset. Assessment of DDRANS is then performed through lidar and SCADA data for different atmospheric conditions. This material is based upon work supported by the National Science Foundation under the I/UCRC WindSTAR, NSF Award IIP 1362033.

  18. Análise numérica de evaporadores do tipo Roll-Bond usados em refrigeradores domésticos

    OpenAIRE

    Suguimoto, Fábio Kenji [UNESP

    2011-01-01

    Neste trabalho apresenta-se um modelo numérico para a simulação do escoamento e da transferência de calor, nos regimes permanente e transiente, ao longo de um evaporador do tipo roll-bond instalado no interior do gabinete de um refrigerador doméstico. Evaporadores roll- bond são amplamente utilizados na maioria dos refrigeradores domésticos no Brasil. A análise desse tipo de evaporador é de fundamental importância para a indústria de refrigeradores domésticos, uma vez que melhora o entendimen...

  19. Does DOM properties or the amount of DOC induces iron reduction in topsoil porewater?

    Science.gov (United States)

    Szalai, Zoltán; Ringer, Marianna; Kiss, Klaudia; Perényi, Katalin; Jakab, Gergely

    2017-04-01

    Iron content of porewater in hydromorphic soils shows high temporal variability. This usually correlates with dissolved organic carbon (DOC) content, but the correlation can be weak in some cases. Some studies suggest that ferrous iron stabilizes organic carbon in dissolved state. On the contrary, other papers report about dissolved iron stabilization by dissolved organic matter (DOM). Present study focuses on this apparent contradiction and on the interaction of organic carbon and iron in hydromorphic soils. Studied gleyic Phaeozems (3 profiles) and mollic Gleysols (3 profiles) are located in Geresdi-dombság (Hungary) and in Danube-Tisza Interfluve (Hungary) respectively. Dynamics of porewater pH, EH, have been recorded by field stations at 20, 40 and 100 cm depth during the growing season with 10 min temporal resolution. Porewater occasionally have also been sampled in each depth. The presence of ferrous iron was detected by dipyridil field test. DOC, dissolved nitrogen (DN) and iron were measured by TOC analyser and fl-AAS. Molecular size and molecular weight were measured by photon correlation spectroscope (DLS and SLS). Textural and mineralogical properties of studied soils were also determined. Relationships among studied parameters were tested by Spearman's rank correlation. The seasonal dynamics of redox potential is primarily controlled by saturation, but spatial differences are also driven by vegetation. The environment is usually reductive for iron oxides between March and July, but intensive daily redox fluctuations could be measured in June and July in some topsoils. Short term temporal variability of redox conditions is depended on the physiological activity of plants. Most of the papers published a range between +100 and +50 mV for iron reduction in aquatic systems. Topsoil porewater measurements show three redox ranges where concentration of dissolved iron has been increased: +320 to +200, +80 to +20 and below-160 mV. These ranges were identified

  20. DomSign: a top-down annotation pipeline to enlarge enzyme space in the protein universe.

    Science.gov (United States)

    Wang, Tianmin; Mori, Hiroshi; Zhang, Chong; Kurokawa, Ken; Xing, Xin-Hui; Yamada, Takuji

    2015-03-21

    Computational predictions of catalytic function are vital for in-depth understanding of enzymes. Because several novel approaches performing better than the common BLAST tool are rarely applied in research, we hypothesized that there is a large gap between the number of known annotated enzymes and the actual number in the protein universe, which significantly limits our ability to extract additional biologically relevant functional information from the available sequencing data. To reliably expand the enzyme space, we developed DomSign, a highly accurate domain signature-based enzyme functional prediction tool to assign Enzyme Commission (EC) digits. DomSign is a top-down prediction engine that yields results comparable, or superior, to those from many benchmark EC number prediction tools, including BLASTP, when a homolog with an identity >30% is not available in the database. Performance tests showed that DomSign is a highly reliable enzyme EC number annotation tool. After multiple tests, the accuracy is thought to be greater than 90%. Thus, DomSign can be applied to large-scale datasets, with the goal of expanding the enzyme space with high fidelity. Using DomSign, we successfully increased the percentage of EC-tagged enzymes from 12% to 30% in UniProt-TrEMBL. In the Kyoto Encyclopedia of Genes and Genomes bacterial database, the percentage of EC-tagged enzymes for each bacterial genome could be increased from 26.0% to 33.2% on average. Metagenomic mining was also efficient, as exemplified by the application of DomSign to the Human Microbiome Project dataset, recovering nearly one million new EC-labeled enzymes. Our results offer preliminarily confirmation of the existence of the hypothesized huge number of "hidden enzymes" in the protein universe, the identification of which could substantially further our understanding of the metabolisms of diverse organisms and also facilitate bioengineering by providing a richer enzyme resource. Furthermore, our results

  1. Biosystematic studies on Dactylis L. 2. Original research. 2.1. Morphological differentiation and occurrence of representatives of the genus Dactylis in Poland. 2.1.2. Distribution of Dactylis glomerata subsp. slovenica (Dom. Dom. in Poland and adjacent regions

    Directory of Open Access Journals (Sweden)

    Marta Mizianty

    2014-01-01

    Full Text Available This paper presents the results of analysis of herbarium materials from Poland, Czechoslovakia, the USSR, East Germany and belonging to the author, as well as data from literature dealing with the distribution of D. glomerata subsp. slovenica (Dom. Dom. in Poland and adjacent regions. It was found that D.g. subsp. slovenica occurs in 33 localities (30 herbarium and 3 literature in Poland. The distribution of this subspecies is presented for the first time for Poland. All the localities of D.g. subsp. slovenica were found in the mountainous parts of Poland (Sudety Mts. and the Carpathians. In territories adjacent to Poland, D.g. subsp. slovenica was found in the Czech Massif and in many stands in the Western and Eastern Carpathians and also in Roztocze Upland.

  2. Gato doméstico: futuro desafio para controle da raiva em áreas urbanas?

    Directory of Open Access Journals (Sweden)

    Gelson Genaro

    2010-02-01

    Full Text Available O objetivo deste artigo foi introduzir debate a respeito da presente e, possivelmente, da futura relevância crescente do gato doméstico, no que se refere à saúde pública, com ênfase para a raiva (animal/urbana. A literatura científica que trata do papel específico do gato em relação às zoonoses ainda é reduzida. Essa espécie está se tornando o mais popular animal de companhia no mundo ocidental urbano, particularmente devido ao estilo de vida adotado pelas pessoas, com reduzido espaço residencial e pouco tempo disponível para se dedicarem aos animais de companhia, o que prejudica especialmente o cão, animal, até então, preferencial. A predominância do gato ainda não é observada no Brasil, contudo, se, em breve, ela for aqui reproduzida ter-se-á que rever as estratégias adotadas, particularmente nas campanhas de vacinação antirrábica. E as características etológicas do felino doméstico deverão ser consideradas para se estabelecer estratégias mais adequadas para que se vacine o número de animais recomendado.This article aims to promote a debate over the actual and (possibly future increasing relevance of the domestic cat concerning public health, with emphasis on rabies (animal/urban control. Scientific literature on the specific role played by cats, especially with respect to zoonoses is scarce. This species is becoming the most popular pet in the western urban context. This is particularly because of the lifestyle adopted by the population, who live in smaller houses and have little time available for pet care, relegating dogs to a less preferential position. Cats do not predominate as domestic animals in Brazil yet, but if these animals soon become the preferential pets in our country, strategies adopted during anti-rabies vaccination campaigns will need to be reviewed. Furthermore, the ethological features of the domestic felid will have to be considered, so that a more suitable approach for the vaccination of

  3. Enhancing SAMOS Data Access in DOMS via a Neo4j Property Graph Database.

    Science.gov (United States)

    Stallard, A. P.; Smith, S. R.; Elya, J. L.

    2016-12-01

    The Shipboard Automated Meteorological and Oceanographic System (SAMOS) initiative provides routine access to high-quality marine meteorological and near-surface oceanographic observations from research vessels. The Distributed Oceanographic Match-Up Service (DOMS) under development is a centralized service that allows researchers to easily match in situ and satellite oceanographic data from distributed sources to facilitate satellite calibration, validation, and retrieval algorithm development. The service currently uses Apache Solr as a backend search engine on each node in the distributed network. While Solr is a high-performance solution that facilitates creation and maintenance of indexed data, it is limited in the sense that its schema is fixed. The property graph model escapes this limitation by creating relationships between data objects. The authors will present the development of the SAMOS Neo4j property graph database including new search possibilities that take advantage of the property graph model, performance comparisons with Apache Solr, and a vision for graph databases as a storage tool for oceanographic data. The integration of the SAMOS Neo4j graph into DOMS will also be described. Currently, Neo4j contains spatial and temporal records from SAMOS which are modeled into a time tree and r-tree using Graph Aware and Spatial plugin tools for Neo4j. These extensions provide callable Java procedures within CYPHER (Neo4j's query language) that generate in-graph structures. Once generated, these structures can be queried using procedures from these libraries, or directly via CYPHER statements. Neo4j excels at performing relationship and path-based queries, which challenge relational-SQL databases because they require memory intensive joins due to the limitation of their design. Consider a user who wants to find records over several years, but only for specific months. If a traditional database only stores timestamps, this type of query would be complex

  4. Joint Mode Selection and Resource Allocation for Downlink Fog Radio Access Networks Supported D2D

    Directory of Open Access Journals (Sweden)

    Xiang Hongyu

    2015-09-01

    Full Text Available Presented as an innovative paradigm incorporating the cloud computing into radio access network, Cloud radio access networks (C-RANs have been shown advantageous in curtailing the capital and operating expenditures as well as providing better services to the customers. However, heavy burden on the non-ideal fronthaul limits performances of CRANs. Here we focus on the alleviation of burden on the fronthaul via the edge devices’ caches and propose a fog computing based RAN (F-RAN architecture with three candidate transmission modes: device to device, local distributed coordination, and global C-RAN. Followed by the proposed simple mode selection scheme, the average energy efficiency (EE of systems optimization problem considering congestion control is presented. Under the Lyapunov framework, the problem is reformulated as a joint mode selection and resource allocation problem, which can be solved by block coordinate descent method. The mathematical analysis and simulation results validate the benefits of F-RAN and an EE-delay tradeoff can be achieved by the proposed algorithm.

  5. Desenvolvendo tecnologia para prevenção e tratamento de emergências domésticas para cegos

    OpenAIRE

    Lorita Marlena Freitag Pagliuca; Estevânia Martins Costa; Nágela Maria Costa; Kelly Monte Sousa

    1996-01-01

    O aprimoramento do desenvolvimento dos órgãos dos sentidos se dá pela percepção de estímulos do meio, o que leva o homem à apreensão do conhecimento. A pessoa privada da visão conta com seus sentidos remanescentes para sua relação com o que a rodeia. O cego está sujeito a emergências domésticas, comuns a todas as pessoas, mas tem dificuldades de acesso a processos educativos que abordem a prevenção e tratamento destas emergências. Em um Curso de Prevenção e Tratamento de Emergências Doméstica...

  6. Fragilidad financiera y fuga doméstica de capitales en el sector productivo colombiano. (1970-1984

    Directory of Open Access Journals (Sweden)

    Alberto Melo

    1989-07-01

    Full Text Available Se examina la crisis financiera que padeció Colombia en 1982 y sus repercusiones en la economía del país, a partir de una premisa básica: las crisis financieras tienen como cusa fundamental el comportamiento financiero de las empresas productivas y de dos hipótesis centrales: la primera señala que entre 1970 y 1982 la economía colombiana pasó de una estructura financiera relativamente fuerte a una cada vez más frágil y la segunda plantea que, en el periodo de análisis, el comportamiento financiero de las empresas no financieras condujo a una fuga doméstica de capital (respecto a sus usos productivos y hacia circuitos financieros domésticos.

  7. Familia y empoderamiento femenino: ingresos, trabajo doméstico y libertad de movimiento de mujeres chontales de Nacajuca, Tabasco

    Directory of Open Access Journals (Sweden)

    María de los Ángeles Pérez Villar

    2009-01-01

    tres aspectos de dicha dimensión: la posibilidad de manejar ingresos propios; la capacidad de negociación de la carga de trabajo doméstico; la libertad de movimiento fuera de casa para realizar actividades extradomésticas. Para lograr este objetivo, se efectuaron entrevistas a profundidad con 27 mujeres indígenas que conforman el Fondo Re gional de Mujeres Chontales de Tabasco (FRMCh. Se construyó una tipología de familias para analizar estos tres aspectos de acuerdo con la composición y ciclo de vida de cada fa milia. Los resultados evidenciaron la capacidad de las mujeres para negociar cambios en el manejo de ingresos y en la libertad de movimiento, pero no en la redistribución del trabajo doméstico. En las conclusiones se reflexiona sobre estos hallazgos a partir de los resultados obtenidos en trabajos similares.

  8. Determinando patrones geográficos del consumo de agua doméstica en Hermosillo, Sonora

    Directory of Open Access Journals (Sweden)

    Arturo Ojeda De La Cruz

    2015-12-01

    Full Text Available En este artículo se presenta un análisis urbano del consumo de agua doméstica identificando su distribución espacial, aplicando la técnica del Análisis Exploratorio de Datos Espaciales (ESDA por sus siglas en inglés y utilizando el sistema GeoDa. Dicho análisis y metodología es aplicado al caso de estudio de la ciudad de Hermosillo, Sonora, México, para determinar los patrones espaciales del consumo de agua, innovando un proceso para la integración de los consumos de agua doméstica a nivel de Colonia y de Área Geoestadística Básica (AGEB aceptable para ciudades en desarrollo en donde prevalece el crecimiento urbano horizontal.

  9. Proactive monitoring of a wind turbine array with lidar measurements, SCADA data and a data-driven RANS solver

    Science.gov (United States)

    Iungo, G.; Said, E. A.; Santhanagopalan, V.; Zhan, L.

    2016-12-01

    Power production of a wind farm and durability of wind turbines are strongly dependent on non-linear wake interactions occurring within a turbine array. Wake dynamics are highly affected by the specific site conditions, such as topography and local atmospheric conditions. Furthermore, contingencies through the life of a wind farm, such as turbine ageing and off-design operations, make prediction of wake interactions and power performance a great challenge in wind energy. In this work, operations of an onshore wind turbine array were monitored through lidar measurements, SCADA and met-tower data. The atmospheric wind field investing the wind farm was estimated by using synergistically the available data through five different methods, which are characterized by different confidence levels. By combining SCADA data and the lidar measurements, it was possible to estimate power losses connected with wake interactions. For this specific array, power losses were estimated to be 4% and 2% of the total power production for stable and convective atmospheric regimes, respectively. The entire dataset was then leveraged for the calibration of a data-driven RANS (DDRANS) solver for prediction of wind turbine wakes and power production. The DDRANS is based on a parabolic formulation of the Navier-Stokes equations with axisymmetry and boundary layer approximations, which allow achieving very low computational costs. Accuracy in prediction of wind turbine wakes and power production is achieved through an optimal tuning of the turbulence closure model. The latter is based on a mixing length model, which was developed based on previous wind turbine wake studies carried out through large eddy simulations and wind tunnel experiments. Several operative conditions of the wind farm under examination were reproduced through DDRANS for different stability regimes, wind directions and wind velocity. The results show that DDRANS is capable of achieving a good level of accuracy in prediction

  10. Homenaje al Profesor Académico Juan Di Doménico.

    Directory of Open Access Journals (Sweden)

    Roberto Vergara Támara

    2004-03-01

    Full Text Available

    Sesión solemne del 25 de septiembre de 2003

    Todos hemos sido, en una u otra forma sus discipulos, por lo que todos sentimos este dia, en el fondo del corazón como de especial regocijo, de expresión de una simpatía que sin duda se ha ganado el
    Profesor Di Doménico a lo largo de su vida, por su manera de ser, por su gentileza, por su severidad cuando fue necesario y por la excelente manera de estimular novedades que ha tenido siempre.

    Juan Mendoza-Vega
    "Una leyenda o un mito"


    Es para mí motivo de especial complacencia festejar los 90 años del Profesor Juan Di Doménico Di Ruggiero, por una generosa designación de la Junta Directiva.
    Cuando el señor Académico Germán Peña me notificó la significativa distinción empecé a rebuscar
    en mi memoria antigua la vida y la obra del Profesor Juan Di Doménico y se me llenaron de exuberancias la antigua y la joven. Irrumpió en mi mente la frase paradigmática: "los árboles no dejan ver el bosque", y al poco andar, con el sable campeón del maestro fui desbrozando esa riqueza vital, ese terremoto humano, ese polifacético personaje universal que fue puliendo sus múltiples facetas con el buril de un escultor de almas y de hombres. Con mucha astucia, con mucho método haremos la sinopsis de este insólito e inverosimil personaje.

    Hubiera querido tener el talento, la inteligencia, la astucia y la donosura del verbo, necesarios para pergeñar tan siquiera un bosquejo de lo que veremos ante esta Honorable Academia y poder orgulloso decir el elogio sísmico de este terremoto humano que ya es leyenda y mito.

    Nació en Panamá en 1913. Sus padres eran italianos: Francisco Di Doménico y María Di Ruggiero. Sus
    primeros estudios los realizó en la Escuela Ricaurte y el Colegio Gimnasio Moderno. Luego se trasladó a

  11. Ontologias de domínio: um estudo das relações conceituais

    Directory of Open Access Journals (Sweden)

    Luana Farias Sales

    Full Text Available No âmbito da elaboração de Ontologias, uma problemática que tem se colocado é a ausência de um padrão teórico-metodológico. Propõe-se então uma sistematização das relações apresentadas nas literaturas da Ciência da Informação, da Terminologia, da Ciência da Computação. A sistematização realizada busca unir as duplas de categorias (relações categoriais com as relações potenciais entre elas (relações formais. A partir da seleção de um corpus da Gene Ontology, foi feita uma análise das definições a fim de identificar as relações já mencionadas na literatura ou descobrir a existência de novas relações. Conclui-se que relações diferentes podem surgir em diferentes domínios e que definições sistematizadas são indispensáveis para o estabelecimento seguro de relações formais.

  12. Seguimento farmacoterapêutico direcionado aos animais domésticos: seria viável?

    Directory of Open Access Journals (Sweden)

    Maria Aparecida NICOLETTI

    2014-12-01

    Full Text Available A atuação global na área da saúde humana tem direcionado seu foco ao cuidado do paciente, tendo o medicamento como segundo plano. Neste sentido, em humanos o seguimento farmacoterapêutico (que faz parte da Atenção Farmacêutica vem sendo uma ferramenta de grande auxílio para a detecção de Problemas Relacionados a Medicamentos (PRM para que possam ser evitados ou identificados visando impedir/minimizar o aparecimento de Resultados Negativos relacionados a Medicamentos (RNM. Considerando a necessidade do sucesso terapêutico como o resultado a ser obtido no cuidado à saúde, o presente trabalho apresenta uma reflexão sobre a possibilidade do modelo de seguimento farmacoterapêutico (Dáder modificado ser adaptado e aplicado à área animal, particularmente, em animais domésticos que fazem uso crônico de medicamentos.

  13. Factores de riesgo relacionados con los accidentes domésticos

    Directory of Open Access Journals (Sweden)

    Nereida Pacios Alfonso

    1998-10-01

    Full Text Available Se realiza observación de los factores de riesgo en 176 hogares durante 12 meses. Se clasifican los apartamentos en 3 grupos según el número de factores detectados. Se visitan trimestralmente y se observan las características de los accidentes domésticos ocurridos. En el 30% de los hogares se concentra el 63% de los accidentes, la morbilidad mayor se concentra en los hogares en que hay mayor número de factores de riesgo, lo que nos hace pensar que el trabajo educativo debe ser planificado y diferenciado, especialmente dirigido a modificar conductas en los hogares de alto riesgo para hacer más efectiva la prevención del fenómenoRisk factors are observed at 176 homes during 12 months. Apartments are classified into 3 groups according to the number of factors. Homes are quarterly visited and the characteristics of the accidents occurred are analyzed. 63 % of the accidents are detected in 30 % of the houses. The highest morbidity is concentrated on those houses having more risk factors, which makes us think that the educative work must be planned and differentiated, specially directed to modify conducts at high risk houses in order to make the prevention of the phenomenon more effective

  14. Reuso de aguas residuales domésticas en agricultura. Una revisión

    Directory of Open Access Journals (Sweden)

    Silva Jorge

    2008-08-01

    Full Text Available

    Las aguas residuales son una importante fuente adicional para satisfacer la demanda del recurso, a causa de la disponibilidad limitada de agua potable para cubrir los requerimientos de las poblaciones, los bajos costos, los beneficios para los suelos agrícolas y la disminución del impacto sobre el ambiente. Sin embargo, el predominio del uso de aguas residuales crudas o diluidas con aguas superficiales y el bajo porcentaje de aguas residuales tratadas en Colombia y en los países de América Latina, en general, generan riesgos en la salud pública, en especial cuando se utilizan para riego de cultivos para consumo directo. Para el reuso de aguas residuales se aconseja realizar siempre un tratamiento preliminar y primario; el tratamiento secundario, además de remover de manera eficiente materia orgánica y sólidos suspendidos, influye directamente sobre la estructura de algunos compuestos, como los de nitrógeno, siendo importante tener en cuenta los requerimientos del cultivo a irrigar y el tipo de suelo. Este artículo propone el uso de aguas residuales domésticas como un recurso alternativo, siempre que se traten y manejen apropiadamente para hacerlo de manera segura en actividades agrícolas, privilegiando el riego de cultivos que sufrirán una transformación industrial posterior.

  15. Comunicación entre perros domésticos (Canis familiaris y hombres

    Directory of Open Access Journals (Sweden)

    Mariana Bentosela

    2007-01-01

    Full Text Available Los perros domésticos (Canis familiaris tienen una serie de habilidades cognitivas que le permiten responder exitosamente a diferentes señales dadas por humanos. Se revisan estudios de cognición social en perros poniendo énfasis en aquellos sobre emisión y comprensión de señales entre ambas especies y en los de aprendizaje por observación de modelos humanos. Las evidencias muestran que esta capacidad es mayor a la que tienen otros cánidos y a la de especies estrechamente emparentadas genéticamente al hombre pero que no convivieron con él; parecen ser producto del proceso de domesticación; por otra parte, los procesos de aprendizaje permiten desarrollarlas al máximo. Es necesario integrar los estudios etológicos con los de la psicología experimental para llegar a comprender este fenómeno.

  16. Efectos psicopatológicos del maltrato doméstico

    Directory of Open Access Journals (Sweden)

    Paulina Paz Rincón

    2004-01-01

    Full Text Available El maltrato doméstico es una situación aversiva que puede provocar un intenso malestarpsicológico. Tradicionalmente, se ha estudiado su repercusión en la adaptación a la vida cotidianay en la salud mental de las víctimas. En este artículo se evalúan sus consecuencias psicológicas en una muestra de 70 mujeres maltratadas. Los resultados apoyan los datos de investigaciones previasacerca de la sintomatología postraumática, encontrándose un porcentaje importante de Trastorno deEstrés Postraumático y de Subsíndrome de Estrés Postraumático. Asimismo, se encontró laexistencia de comorbilidad con depresión. Sin embargo, el porcentaje de mujeres que presentabaalgún otro trastorno de ansiedad fue inferior al señalado en trabajos anteriores, y ninguna de ellaspresentó problemas de abuso de alcohol o drogas. Se describe la presencia de determinadas variablesconcomitantes, destacándose el nivel de inadaptación general y la baja autoestima. Se apuntanconsideraciones de cara al tratamiento a partir de la sintomatología específica encontrada.

  17. Cascading influence of inorganic nitrogen sources on DOM production, composition, lability and microbial community structure in the open ocean

    OpenAIRE

    Goldberg, SJ; Nelson, CE; Viviani, DA; Shulse, CN; Church, MJ

    2017-01-01

    © 2017 Society for Applied Microbiology and John Wiley & Sons Ltd Nitrogen frequently limits oceanic photosynthesis and the availability of inorganic nitrogen sources in the surface oceans is shifting with global change. We evaluated the potential for abrupt increases in inorganic N sources to induce cascading effects on dissolved organic matter (DOM) and microbial communities in the surface ocean. We collected water from 5 m depth in the central North Pacific and amended duplicate 20 liter...

  18. Feminismo y mujeres migrantes en Costa Rica. Articulaciones pendientes en torno al trabajo doméstico remunerado

    Directory of Open Access Journals (Sweden)

    Karina Fonseca Vindas

    2008-08-01

    Full Text Available ESTE ARTÍCULO PROPONE UN ACERCAMIENTO CRÍTICO A LA SITUACIÓN QUE enfrentan miles de mujeres trabajadoras domésticas en Costa Rica, principalmente las difíciles condiciones laborales que deben soportar mujeres migrantes nicaragüenses al ser contratadas en casas de habitación costarricenses. Ellas son quienes sufrenlos mayores atropellos y suelen experimentar un grado más alto de desprotección respecto de las nacionales.Las vivencias de las trabajadoras domésticas evidencian los serios conflictos que rodean los esfuerzos orientados a la concreción de articulaciones teóricas y prácticas entre la condición de ser mujer, la clase social a la que se pertenezca y la nacionalidad. Para efectos de este trabajo, cobra especial interés además, lanecesidad de reconocer la labor doméstica como una ocupación homologable a los otros trabajos contemplados en la legislación laboral de Costa Rica, así como la urgencia de que las reivindicaciones asociadas al trabajo doméstico remuneradoadquieran mayor protagonismo en las agendas derivadas de la conciencia feminista dominante.Si bien las organizaciones de mujeres han abierto significativas rutas hacia la reducción de la desigualdad histórica entre hombres y mujeres, es indispensable reconocer que las mujeres no son un grupo homogéneo, sino que experimentan tensiones y contradicciones a lo interno de su condición, que vuelve sumamente compleja la justificada búsqueda de una real equidad de género.

  19. O ensaio sobre o dom de Marcel Mauss: um texto pioneiro da crítica decolonial

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    Paulo Henrique Martins

    2014-08-01

    Full Text Available O objetivo deste artigo é mostrar que Marcel Mauss, em seu Ensaio sobre o dom, publicado em 1924, desenvolve uma reflexão pós-colonial avant la lettre que estrutura toda a sua crítica antiutilitarista do ocidentalismo e que pode esclarecer uma série de aspectos da crítica decolonial, especialmente em suas relações atuais com o pensamento antiutilitarista desenvolvido na Europa.

  20. Deconstrucción del discurso bélico en el Poema Heroico de Hernando Domínguez

    Directory of Open Access Journals (Sweden)

    Ana Carolina Ochoa Roa

    2016-12-01

    Full Text Available El propósito de este análisis es demostrar la manera en la cual el escritor neogranadino Hernando Domínguez Camargo deconstruye, a través de sus octavas, la visión bélica que exalta la Conquista española, por medio de un análisis meticuloso de algunos momentos de su obra magna: el Poema Heroico.

  1. Effects of dissolved organic matters (DOMs) on membrane fouling in anaerobic ceramic membrane bioreactors (AnCMBRs) treating domestic wastewater.

    Science.gov (United States)

    Yue, Xiaodi; Koh, Yoong Keat Kelvin; Ng, How Yong

    2015-12-01

    Anaerobic membrane bioreactors (AnMBRs) have been regarded as a potential solution to achieve energy neutrality in the future wastewater treatment plants. Coupling ceramic membranes into AnMBRs offers great potential as ceramic membranes are resistant to corrosive chemicals such as cleaning reagents and harsh environmental conditions such as high temperature. In this study, ceramic membranes with pore sizes of 80, 200 and 300 nm were individually mounted in three anaerobic ceramic membrane bioreactors (AnCMBRs) treating real domestic wastewater to examine the treatment efficiencies and to elucidate the effects of dissolved organic matters (DOMs) on fouling behaviours. The average overall chemical oxygen demands (COD) removal efficiencies could reach around 86-88%. Although CH4 productions were around 0.3 L/g CODutilised, about 67% of CH4 generated was dissolved in the liquid phase and lost in the permeate. When filtering mixed liquor of similar properties, smaller pore-sized membranes fouled slower in long-term operations due to lower occurrence of pore blockages. However, total organic removal efficiencies could not explain the fouling behaviours. Liquid chromatography-organic carbon detection, fluorescence spectrophotometer and high performance liquid chromatography coupled with fluorescence and ultra-violet detectors were used to analyse the DOMs in detail. The major foulants were identified to be biopolymers that were produced in microbial activities. One of the main components of biopolymers--proteins--led to different fouling behaviours. It is postulated that the proteins could pass through porous cake layers to create pore blockages in membranes. Hence, concentrations of the DOMs in the soluble fraction of mixed liquor (SML) could not predict membrane fouling because different components in the DOMs might have different interactions with membranes. Copyright © 2015 Elsevier Ltd. All rights reserved.

  2. Trabajo doméstico y migraciones latinoamericanas. Desde Argentina, hallazgos y reflexiones frente a los destinos extrarregionales

    Directory of Open Access Journals (Sweden)

    Carolina Rosas

    2015-01-01

    Full Text Available Con el fin de contribuir al debate en torno a la participación de las mujeres migrantes en el trabajo doméstico remunerado, el objetivo de este artículo es analizar dos aspectos en los que Argentina (principal destino intrarregional presenta contrastes con Estados Unidos y España (principales destinos extrarregionales. Mediante el análisis de encues - ta se estudia la composición del sector doméstico en la última década según la condición migratoria de las ocupadas; posteriormente, por medio de un análisis jurídico, se descri - ben las legislaciones que regulan dicha relación laboral. Entre los principales resultados se encuentra que el sector del trabajo doméstico está conformado principalmente por mujeres argentinas no migrantes, y que depende cada vez menos de la fuerza de trabajo migrante interna. A diferencia de lo que ocurre en los destinos extrarregionales, dicho sector no depende de la fuerza de trabajo extranjera. Se demuestra además que esa composición varía según la región/aglomerado considerado. Por último, se observa que los tres países considerados han realizado avances legislativos en los últimos años, y que en aspectos específicos la ley argentina otorga mayor protección

  3. Mercados de trabajo secundarios e inmigración: el servicio doméstico en Estados Unidos

    Directory of Open Access Journals (Sweden)

    Marina Ariza

    2011-01-01

    Full Text Available El servicio doméstico figura entre los mercados de trabajo secundarios que han cobrado vigencia en el contexto de la globalización. Su dinamismo se relaciona con la demanda de fuerza de trabajo femenina barata para satisfacer necesidades de atención en la esfera de la reproducción doméstica. La caracterización del mercado de trabajo del servicio doméstico en Estados Unidos a principios del siglo XXI con base en datos de encuesta muestra que -ahora como antaño- su crecimiento descansa principalmente en la afluencia de fuerza de trabajo inmigrante, que en nuestros días es principalmente latinoamericana. El nivel de pobreza que acusan y su baja escolaridad, corroboran que el crecimiento de este mercado de trabajo en las sociedades desarrolladas es una más de las secuelas regresivas del mundo del trabajo en el contexto de la globalización.

  4. La importancia del trabajo doméstico desde una óptica regional y de género

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    Myrna Limas Hernández

    2005-01-01

    Full Text Available La compleja naturaleza de las estadísticas de género dificulta utilizarlas según la metodología tradicional. Los reportes oficiales de corte nacional e internacional adolecen de vacíos estadísticos singulares. Partiendo de esta referencia, el presente artículo se orienta a revisar la forma en que el trabajo doméstico y extradoméstico, protagonizado por las mujeres, puede integrarse en las estadísticas macroeconómicas. En particular se aborda el caso de Ciudad Juárez, Chihuahua (México para hacer el análisis. Específicamente la revisión se centra en detectar si los ejercicios cotidianos domésticos y extradomésticos contribuyen y bajo qué posibilidades al bienestar regional. Por último se exponen los Indicadores de Progreso Auténtico que constituyen un proyecto de reciente construcción con el que se busca revalorar el entorno sectorial de las localidades, incluyendo la esfera doméstica, de tal forma que el diseño de políticas públicas sea más acertado.

  5. Retos para mujeres inmigrantes sobrevivientes de violencia doméstica en nuevos destinos migratorios en Estados Unidos

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    Elithet SILVA-MARTÍNEZ

    2012-01-01

    Full Text Available En las últimas décadas se ha observado un flujo de inmigrantes latinoamericanos/as hacia Estados Unidos, particularmente a las áreas urbanas. Investigaciones sociológicas han evidenciado un cambio en los patrones migratorios hacia destinos nuevos en ese país, particularmente hacia zonas rurales del medio oeste. Estos cambios tienen implicaciones en sectores de población que experimentan múltiples opresiones, como lo son las mujeres inmigrantes. En este artículo se utiliza una perspectiva mujerista y feminista chicana para examinar factores relacionados con la vio lencia doméstica en comunidades de inmigrantes en el estado de Iowa. El objetivo es promover el activismo para proteger los derechos de las mujeres que sufren violencia doméstica y son revictimizadas por ser latinas, mujeres, inmigrantes e hispanohablantes. Este análisis se basó en literatura sobre género y violencia en Estados Unidos y se enmarcó en un estudio etnográfico realizado con mujeres inmigrantes me xi canas sobrevivientes de violencia doméstica.

  6. Improved CO Oxidation Activity of 3DOM Pr-Doped Ceria Catalysts: Something Other Than an Ordered Macroporous Structure

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    Arantxa Davó-Quiñonero

    2017-02-01

    Full Text Available It is demonstrated that the synthesis procedure for preparing three-dimensionally ordered macroporous (3DOM Pr-doped ceria catalysts using a polymethylmethacrylate (PMMA template not only affects the porous structure, but also the chemistry of the ceria surface. The PMMA template does not affect the crystalline features (type of phases, crystallite size, and cell parameter of Pr-doped ceria, Ce and Pr location into the particles, and the bulk reduction of the Ce-Pr mixed oxide catalysts. On the contrary, the utilization of the PMMA template improves both the porosity and surface redox properties. 3DOM Ce-Pr mixed oxide catalysts combine micro, meso, and macropores, the most area being in the macropore range, while a reference unshaped catalyst presents poor porosity in all ranges. However, the catalyzed CO oxidation rates do not correlate with the surface area of the catalysts (neither micro nor meso/macro. The Ce-Pr-3DOM catalyst also presents improved surface reducibility with regards to the counterpart reference material prepared without the template, and improved redox behavior under reaction conditions; that is, it has a higher area and this area is reduced and reoxidized more easily. X-ray photoelectron spectroscopy analysis evidences that this is mainly attributed to praseodymium cations, which accomplish redox cycles more easily than cerium cations.

  7. The decline of Dom Pedro II's empire and health: neurophatogenic implications O declínio do império e da saúde de Dom Pedro II: implicações neuropatogênicas

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    Marleide da Mota Gomes

    2007-12-01

    Full Text Available The main objective of this paper is to know the medical doctors of the Emperor, the preconized treatment, and the knowledge about diabetes at that time, its repercussions on the Emperor's nervous system, and the related political implications. A narrative revision was made, based on primary and secondary sources. Dom Pedro II was examined by the aristocracy of the medicine at the time, especially Jean-Martin Charcot, amongst the doctors of international reputation, and Cláudio Velho da Motta Maia, amongst the Brazilian doctors. Charcot diagnosed in the Monarch: mental stress, diabetic neuropathy, and a cerebral vascular lesion, probably a stroke, that he differentiated from other vascular obliterations elsewhere. He demonstrated his knowledge about diabetic neuropathy, possible topographical alternatives to justify the urinary incontinence, and Dom Pedro's weakness in the legs. Throughout his illness, Dom Pedro II presented others manifestations that contributed to his physical fragility, and that, certainly too, to his political decline, deposition and the proclamation of the Brazilian Republic.O objetivo principal deste artigo é conhecer os médicos do Imperador, o tratamento preconizado e o conhecimento da ocasião sobre o diabetes, principalmente sobre suas repercussões no sistema nervoso do imperador e suas implicações políticas. Isso foi feito por uma revisão narrativa, baseado em fontes primárias e secundárias. Dom Pedro II foi examinado na ocasião pela aristocracia da medicina, a ressaltar Jean-Martin Charcot, dentre os médicos de reputação internacional, e Cláudio Velho da Motta Maia, dentre os brasileiros. Charcot diagnosticou no Monarca, além de tensão mental, neuropatia diabética e quadro vascular cerebral que ele diferenciou de outras obliterações vasculares em localizações diversas. Ele demonstrou o seu conhecimento sobre a neuropatia diabética, possíveis alternativas topográficas para justificar a incontin

  8. Analysis of multiuser mixed RF/FSO relay networks for performance improvements in Cloud Computing-Based Radio Access Networks (CC-RANs)

    Science.gov (United States)

    Alimi, Isiaka A.; Monteiro, Paulo P.; Teixeira, António L.

    2017-11-01

    The key paths toward the fifth generation (5G) network requirements are towards centralized processing and small-cell densification systems that are implemented on the cloud computing-based radio access networks (CC-RANs). The increasing recognitions of the CC-RANs can be attributed to their valuable features regarding system performance optimization and cost-effectiveness. Nevertheless, realization of the stringent requirements of the fronthaul that connects the network elements is highly demanding. In this paper, considering the small-cell network architectures, we present multiuser mixed radio-frequency/free-space optical (RF/FSO) relay networks as feasible technologies for the alleviation of the stringent requirements in the CC-RANs. In this study, we use the end-to-end (e2e) outage probability, average symbol error probability (ASEP), and ergodic channel capacity as the performance metrics in our analysis. Simulation results show the suitability of deployment of mixed RF/FSO schemes in the real-life scenarios.

  9. Numerical investigation of the vortex-induced vibration of an elastically mounted circular cylinder at high Reynolds number (Re = 104 and low mass ratio using the RANS code.

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    Niaz Bahadur Khan

    Full Text Available This study numerically investigates the vortex-induced vibration (VIV of an elastically mounted rigid cylinder by using Reynolds-averaged Navier-Stokes (RANS equations with computational fluid dynamic (CFD tools. CFD analysis is performed for a fixed-cylinder case with Reynolds number (Re = 104 and for a cylinder that is free to oscillate in the transverse direction and possesses a low mass-damping ratio and Re = 104. Previously, similar studies have been performed with 3-dimensional and comparatively expensive turbulent models. In the current study, the capability and accuracy of the RANS model are validated, and the results of this model are compared with those of detached eddy simulation, direct numerical simulation, and large eddy simulation models. All three response branches and the maximum amplitude are well captured. The 2-dimensional case with the RANS shear-stress transport k-w model, which involves minimal computational cost, is reliable and appropriate for analyzing the characteristics of VIV.

  10. Seasonal variation in the nature of DOM in a river and drinking water reservoir of a closed catchment.

    Science.gov (United States)

    Awad, John; van Leeuwen, John; Chow, Christopher W K; Smernik, Ronald J; Anderson, Sharolyn J; Cox, Jim W

    2017-01-01

    Dissolved organic matter (DOM) in surface waters used for drinking purposes can vary markedly in character depending on its source within catchments and the timing and intensity of rainfall events. Here we report the findings of a study on the character and concentration of DOM in waters collected during different seasons from Myponga River and Reservoir, South Australia. The character of DOM was assessed in terms of its treatability by enhanced coagulation and potential for disinfection by-product i.e. trihalomethane (THM) formation. During the wet seasons (winter and spring), water samples from the river had higher DOC concentrations (X¯: 21 mg/L) and DOM of higher average molecular weight (AMW: 1526 Da) than waters collected during the dry seasons (summer and autumn: DOC: 13 mg/L; AMW: 1385 Da). Even though these features led to an increase in the percentage removal of organics by coagulation with alum (64% for wet compared with 53% for dry season samples) and a lower alum dose rate (10 versus 15 mg alum/mg DOC removal), there was a higher THM formation potential (THMFP) from wet season waters (treated waters: 217 μg/L vs 172 μg/L). For reservoir waters, samples collected during the wet seasons had an average DOC concentration (X¯: 15 mg/L), percentage removal of organics by alum (54%), alum dose rates (13 mg/mg DOC) and THMFP (treated waters: 207 μg/L) that were similar to samples collected during the dry seasons (mean DOC: 15 mg/L; removal of organics: 52%; alum dose rate: 13 mg/mg DOC; THMFP: 212 μg/L for treated waters). These results show that DOM present in river waters and treatability by alum are highly impacted by seasonal environmental variations. However these in reservoir waters exhibit less seasonal variability. Storage of large volumes of water in the reservoir enables mixing of influent waters and stabilization of water quality. Crown Copyright © 2016. Published by Elsevier Ltd. All rights reserved.

  11. Mujeres de Guadalajara y violencia doméstica: resultados de un estudio piloto Women from Guadalajara and domestic violence: a pilot study

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    Juan Carlos Ramírez Rodríguez

    1996-09-01

    Full Text Available La violencia doméstica contra la mujer es un problema médico social que continúa soslayado por las instituciones, no sólo de salud, sino en general por la sociedad mexicana. Existen incipientes investigaciones que muestran la magnitud de este fenómeno. Se realizó una encuesta piloto en 57 mujeres de Guadalajara, México, seleccionadas mediante un muestreo polietápico. Se encontró que el 46% de las mujeres habían sufrido de violencia. El perpetrador más frecuente fue el compañero/esposo (73%. De las mujeres que han sufrido de violencia por parte del esposo, la violencia emocional se identificó en el 33%, la violencia física con 19% y la sexual con 12%.Domestic violence against women is a sociomedical problem that continues to be overlooked by health institutions specifically and Mexican society as a whole. There are a handful of initial studies on this issue that report on the problem in specific areas of the country. This is a pilot study on 57 women from Guadalajara, Mexico, selected through a multi-stage random sample. Some 46% of the women had suffered domestic violence. The partner was identified as the perpetrator in 73% of these cases. Among these women, 33% had been emotionally abused, 19% physically abused, and 12% sexually abused.

  12. Teor de macronutrientes em girassol ornamental sob doses de esterco e efluente doméstico

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    Eric Mateus Soares Dias

    2017-07-01

    Full Text Available Os estercos são subprodutos da pecuária por vezes descartados, mesmo sendo potencialmente adubos orgânicos. A água residuária também é considerada outro subproduto de potencial para reuso na agricultura. Objetivou-se avaliar o teor de nitrogênio, fósforo e potássio em plantas de girassol ornamental (Helianthus annuus L., cv. Sol Noturno adubadas com esterco bovino e irrigadas com efluente doméstico tratado. Os fatores estudados foram 2 tipos de água de irrigação (abastecimento e efluente doméstico e 4 doses de esterco bovino (5, 10, 15 e 20%, com base em peso. Aos 60 dias depois do plantio (DAP, as plantas de girassol foram colhidas e fez-se a preparação das amostras de parte das plantas (raízes, caules, folhas e flor, as quais foram secadas em estufa com ventilação forçada a 62 °C, durante 72 horas e em seguida, realizou-se a determinação dos teores de nitrogênio (N, fósforo (P e potássio (K em uma amostra composta de diferentes partes. O teor de N foi influenciado positivamente pelas doses de 10, 15 e 20% de esterco bovino, sem diferença entre elas e, embora não significativamente, a água residuária proporcionou os maiores teores em todos os macronutrientes avaliados.Macronutrients content in ornamental sunflower under bovine Manure and WastewaterAbstract: The manures are byproducts of cattle, sometimes discarded, even though potentially organic fertilizers. Similarly, the wastewater should be considered another potential byproduct of reuse in agriculture. The objective of this work was to evaluate the content of nitrogen, phosphorus and potassium in ornamental sunflower plants (Helianthus annuus L., cv. Sol Not urno fertilized with cattle manure and irrigated with wastewater. The factors two types of water (supply and wastewater and four levels of bovine manure (5, 10, 15 and 20%, based on weight of soil were used. At 60 days after sowing (DAS, plants were harvested and divided into plant parts (roots, stems

  13. Pluriatividade, pobreza rural e serviço doméstico remunerado

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    Carlos Alves do Nascimento

    2004-06-01

    Full Text Available Este trabalho se propôs analisar, com base nos microdados da Pesquisa Nacional por Amostra de Domicílios (PNAD - anos 1992-1999 e 2001 -, a participação da renda do serviço doméstico remunerado entre determinados tipos de famílias rurais pobres que apresentaram taxas de crescimento negativas nos anos 90, demonstrando que, em diversos casos, a renda do serviço doméstico explica melhor a redução da pobreza rural do que as transferências governamentais (aposentadorias e pensões. Para tanto, realizamos uma breve análise da evolução dos diferentes tipos de famílias extensas rurais (e pobres nos anos 90, além de uma análise comparativa entre as Grandes Regiões do país no tocante às rendas média e per capita dos diferentes tipos de famílias rurais adotando como referência o ano de 2001. Além disso, procuramos mostrar que a redução de famílias pobres agrícolas se deve, neste caso, também ao fato destas estarem se tornando famílias de não-ocupados, residentes no meio rural, e não somente em virtude de êxodos agrícola (substituição de atividades agrícolas por atividades não-agrícolas e/ou rural-urbano. Para testar estas hipóteses, adotamos como referência a linha de pobreza construída por Takagi et al (2001 - de U$ 1,08 - e a nova tipologia de famílias extensas desenvolvida pelo Projeto Rurbano.This paper tries to analyze, based on the micro data of the Pesquisa Nacional por Amostra de Domicílios (PNDA - years 1992-1999 and 2001 - the share of the paid domestic service income between some types of poor rural families that presented negative growing taxes in the 90s, showing that in different cases, the paid domestic service income better explains the reduction of rural poverty than governmental transferences (retirements and pensions. We made a brief analysis of the evolution of different types of rural extensive families (and poor in the 90s, besides a comparative analysis among the big regions of the country

  14. Uso del suelo como tratamiento secundario de aguas residuales domésticas

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    Wilber J. Perez-FLores

    2017-03-01

    Full Text Available El propósito del estudio es evaluar la eficiencia de remoción de contaminantes de aguas residuales domésticas (ARD usando el suelo como tratamiento, para utilizarlo como una alternativa al alcance de poblaciones sin acceso a sistemas de alcantarillado y tratamiento de ARD. Se construyó un sistema piloto de tratamiento de ARD compuesto por una fosa séptica y zanjas de infiltración, el cual funciona por percolación en el subsuelo, donde el agua atraviesa una capa de piedrín y luego se percola en el suelo. El estudio se realizó en la planta experimental de tratamiento de ARD en la ciudad de Guatemala, durante octubre 2014 a mayo del 2015. Se tomaron como parámetros los indicados en el Reglamento de descargas y reúsos de las aguas residuales y la disposición de lodos. Los análisis se realizaron en el Laboratorio Unificado de Química y Microbiología Sanitaria, a excepción de los metales pesados, aceites y grasas. La evaluación del rendimiento del sistema piloto de tratamiento de ARD demostró una eficiente remoción de contaminantes, con resultados en sólidos suspendidos de 99%, color 95%, DBO5de 99%, DQO de 98%, fósforo de 87% y coliformes fecales de 93%. Respecto al nitrógeno se eliminaron los resultados extremos, obteniéndose una eficiencia de remoción de 23%. Se comprobó que el suelo es capaz de remover con eficacia la mayoría de contaminantes de las ARD a excepción del nitrógeno, el cual requiere un estudio más detallado para entender su comportamiento en el proceso.

  15. Radiografia intraoral e convencional da hemiarcada superior direita de gatos domésticos

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    A.C. Nepomuceno

    2013-02-01

    Full Text Available A proposta com este trabalho foi avaliar a hemiarcada superior direita de gatos domésticos por meio de técnicas radiográficas odontológicas do paralelismo, empregando-se filmes intraorais aos posicionadores de Han Shin. As imagens obtidas por essa metodologia foram correlacionadas com as técnicas radiográficas convencionais (extraorais, com o intuito de se estabelecerem vantagens ou desvantagens para detectar possíveis afecções dentais e periodontais. Foram utilizados 30 gatos, sem raça definida, 17 machos e 13 fêmeas, faixa etária entre um e três anos, confinados em gatis do Departamento de Zootecnia da Universidade Federal de Lavras/MG. Com os animais sob anestesia geral, foram realizadas radiografias da hemiarcada superior direita, incluindo três incisivos, um canino, três pré-molares e um molar em radiografias intraorais e extraorais. As imagens radiográficas foram analisadas e efetuaram-se comparações qualitativas entre pares intraorais e convencionais dos mesmos animais. Para se estabelecer a técnica radiográfica dental mais bem adaptada, foram realizadas análises estatísticas pelo teste de McNemar (qui-quadrado modificado. A técnica intraoral mostrou ser superior à extraoral (P<0,05, para achados referentes a espaço periodontal aumentado, canal radicular amplo e arredondamento de ápice, e também para a avaliação mais bem detalhada de dentes caninos, pré-molares e molares em gatos.

  16. Spectroscopic characterization of DOM and the nitrogen removal mechanism during wastewater reclamation plant

    Science.gov (United States)

    Wang, Lei; Li, Ying-Jun; Xiong, Ying; Tan, Wen-Bing; Zhang, Lie-Yu; Li, Xiang; Wang, Xiao-Shu; Xu, Jian-feng; Li, Tong-Tong; Wang, Jin-Sheng; Cai, Ming-Xuan; Xi, Bei-Dou; Wang, Di-Hua

    2017-01-01

    The performance of the Sha-he wastewater reclamation plant was evaluated in this study. To remove residual nitrogen after Anaerobic-Anoxic-Oxic (A2O) treatment, three multistage Anoxic-Oxic (A/O) were added to investigate the nitrogen removal efficiency and its mechanism. In addition, the constituents and evolution of dissolved organic matter (DOM) during wastewater reclamation was also investigated using a method combining fluorescence spectroscopy with fluorescence regional integration (FRI). The results suggested that multistage A/O treatment can effectively improve the nitrogen removal ability under low concentrations of carbon sources. The total nitrogen (TN) exhibits significantly positive correlation with fulvic acid-like materials and humic acid-like materials. The correlation coefficient for TN and fulvic acid-like substances (R2 = 0.810, P < 0.01) removal was greater than that of humic acid-like substances (R2 = 0.636, P < 0.05). The results indicate that nitrogen removal may be achieved with the fulvic-like and humic-like substances, and the removal effects were higher by fulvic acid-like substances than humic-like substances, mostly due to that the latter were relatively more difficult to be utilized as carbon source during the nitrogen removal process. The effluent water quality of biological treatment reached the first grade A standard of “Cities sewage treatment plant pollutant discharge standard” (GB18918-2002). In addition, the effluent from the membrane bioreactor reached the “Standards of reclaimed water quality” (SL368-2006). PMID:29149172

  17. Tuberculose em felinos domésticos (Felis catus no sul do Rio Grande do Sul

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    Daniel M. Alves

    Full Text Available RESUMO: Descrevem-se os aspectos clínico patológicos de quatro casos de tuberculose em felinos domésticos no Sul do Rio Grande do sul. Foi realizado um estudo retrospectivo dos casos diagnosticados como tuberculose em gatos necropsiados no Laboratório Regional de Diagnóstico da Universidade Federal de Pelotas (LRD/UFPel no período de janeiro de 2000 a dezembro de 2014. Em dois casos a amplificação da sequência genética IS6110 específica para Mycobacterium tuberculosis demonstrou que a doença era de origem humana. Os outros dois foram positivos para Mycobacterium spp. Os sinais clínicos caracterizaram-se por emagrecimento progressivo, anorexia e dispneia. As alterações macroscópicas evidenciadas eram de caquexia, aumento de volume dos linfonodos submandibulares com áreas focais de aspecto caseoso ao corte. Nos pulmões havia áreas multifocais a coalescentes amareladas de aspecto caseoso, discretamente elevadas e firmes na superfície pleural. Histologicamente havia broncopneumonia e linfadenite granulomatosas. A coloração de Ziehl-Neelsen evidenciou a presença de bacilos álcool-ácidos resistentes. Houve imunomarcação positiva para micobactéria pela técnica de imuno-histoquímica. Alerta-se para a importância da tuberculose felina como um problema de saúde pública pois gatos infectados podem servir de fonte para a disseminação das micobactérias no ambiente, além de serem sentinelas para a ocorrência da enfermidade em seres humanos.

  18. Mulheres que sofrem violência doméstica: contribuições da psicanálise

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    Gabriela Quadros de Lima

    2011-12-01

    Full Text Available Este estudo busca compreender a influência da história de vida na escolha conjugal de mulheres que sofrem violência doméstica e os fatores que levam à admissão e/ou tolerância da repetição de um comportamento inadmissível. Participaram 12 mulheres, maiores de 18 anos de diferentes raças e níveis socioeconômicos e de escolaridade que sofreram violência doméstica perpetrada pelo parceiro íntimo, localizadas em dois Centros de Referência às Vítimas de Violência de Porto Alegre. As participantes preencheram uma Ficha de dados pessoais e sociodemográficos e responderam a uma entrevista semiestruturada. As entrevistas foram analisadas e categorizadas através da técnica de análise de conteúdo, e para a interpretação dos dados lançou-se mão da teoria psicanalítica. Os aspectos abordados permitem compreender a violência doméstica como resultante de uma história de vida marcada por vivências traumáticas que move estas mulheres, através da compulsão à repetição, à realização de escolhas conjugais que propiciam um cenário violento.

  19. Adsorptive removal of dissolved organic matter (DOM) in landfill leachate by iron oxide nanoparticles (FeONPs)

    Science.gov (United States)

    Ghani, Zaidi Ab; Yusoff, Mohd Suffian; Zaman, Nastaein Qamaruz; Andas, Jeyashelly; Aziz, Hamidi Abdul

    2017-10-01

    A study was conducted to investigate the efficiency of iron oxide nanoparticle (FeONPs) adsorption for removing of DOM in landfill leachate. FeONPs was directly prepared via sodium borohydride (KBH4) reduction method. Adsorption kinetics, isotherm and thermodynamic studies were developed to design the model for DOM removal. Pseudo first-order and pseudo second-order model have been studied to fit the experimental data. The regression results showed that the adsorption kinetics were more accurately represented by a pseudo second-order model. The Weber-Morris intraparticle diffusion model was used to analyze the adsorption kinetics data. The plot of qt versus t1/2 represents multi linearity, which showed that the adsorption processes occurred in more than one step. Adsorption isotherms were analyzed by Langmuir, Freundlich, Tempkin and Dubinin-Radushkevich, isotherms model. Equilibrium data were well fitted to the Dubinin- Radushkevich isotherm model. Maximum monolayer adsorption based on Langmuir was calculated to be 21.74 mg/g. Thermodynamic parameters such as free energy changes (ΔG°), enthalpy (ΔH°) and entropy (ΔS°) were evaluated between temperatures of 25 °C and 40 °C. The ΔG° was noticed progressively decrease from -9.620 -9.820 -10.021, and -10.222 kJ/mol as the temperature increase. The ΔH° and ΔS° values were found to be 2.350 kJ/mol and 40.165 J/mol.K respectively. The results showed that the overall adsorption process was endothermic and spontaneous. The results from this study suggested that FeNPs could be a viable adsorbent in managing higher DOM problems associated with landfill leachate.

  20. Aspectos morfométricos do timo em gatos domésticos (Felis domesticus

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    Camila E. Barroso

    2012-12-01

    Full Text Available O timo é um órgão linfático primário que desenvolve sua atividade em organismos jovens. Apesar de sua função ser responsável por mecanismos fundamentais na aquisição das defesas e conseqüentes respostas orgânicas, ela ainda não está totalmente esclarecida, nem tampouco as bases morfológicas que respondem por tais funções, como o processo de desenvolvimento e involução do órgão. Objetivou-se analisar e caracterizar os aspectos morfológicos do timo, tais como seu tamanho e volume, e aspectos histológicos do timo em gatos, correlacionando o sexo e o desenvolvimento etário. Doze timos provenientes de fetos de gatos domésticos (Felis domesticus sem raça definida (SRD, machos e fêmeas, separados em três grupos etários. O timo apresentou-se com uma coloração rosa-pálida e com duas porções, a torácica e a cervical, sendo que cada uma delas possuía um lobo direito e um lobo esquerdo em sua maioria. A porção torácica localizava-se em região de mediastino cranial, entre os pulmões e à base do coração. E a porção cervical estendia-se além das costelas em sentido cranial, estando localizada ventralmente à traqueia. A estrutura celular do timo demonstrou-se organizada com a presença de agregados concêntricos, os chamados corpúsculos tímicos, formados por células epiteliais, sustentada por uma cápsula de tecido conjuntivo de onde partiam septos que ao penetrar no órgão dividia-o em lóbulos. Ocorreram variações significativas quanto à lobação e as dimensões do timo entre indivíduos da mesma faixa etária, e entre sexos diferentes. Os valores relativos ao comprimento, espessura e largura, de maneira geral, apresentaram aumento, em conformidade ao desenvolvimento dos animais, mas com diferenças entre os sexos.

  1. Eficacia de cinco desinfectantes para la reducción bacteriana doméstica

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    Julián Stambullian

    2011-06-01

    Full Text Available El uso adecuado de hipoclorito de sodio, sales de amonio cuaternario y triclosán ha demostrado ser eficaz para eliminar gérmenes dentro del hogar. Nuestro objetivo fue evaluar la eficacia inmediata, a la semana y al mes del uso controlado de cinco productos con estos componentes, comparados con otros productos de uso habitual. Se incluyeron 32 hogares de clase media de la Ciudad de Buenos Aires y la periferia en un estudio con intervención, abierto, aleatorizado, y de grupos paralelos, durante 6 meses. La mitad de los hogares fue seleccionada para usar hipoclorito de sodio, sales de amonio cuaternario y triclosán en la cocina y el baño durante un mes. El grupo control mantuvo prácticas habituales de limpieza doméstica. Se tomaron muestras para recuento y tipificación bacteriana de los sitios estudiados: muestras basales (sin discriminación de grupo en cocina, que presentaron recuento bacteriano promedio de 66.0 UFC/cm²; baño: 40.1 UFC/cm². Las muestras inmediatas a la limpieza (sin discriminación de grupo: en cocina: 0.8 UFC/cm²; baño: <1 UFC/cm². A la semana (grupo intervenido vs. grupo control: cocina 18.0 vs. 32.5 UFC/cm²; baño 12.7 vs. 7.7 UFC/cm². Al mes (intervenido vs. control: cocina: 60.1 vs. 62.1 UFC/cm²; baño: 37.0 vs. 42.0 UFC/cm². Se observó una notable disminución de la carga bacteriana en ambos grupos, lo que sugiere que no sólo la calidad de los productos sino también la educación en el uso desempeñan un papel clave en la desinfección del hogar. Este enfoque podría ser una herramienta importante para prevenir infecciones transmitidas por alimentos, dado que los coliformes fecales predominaron ampliamente en todas las muestras tipificadas.

  2. Connecting tropical river DOM and POM to the landscape with lignin

    Science.gov (United States)

    Hernes, Peter J.; Dyda, Rachael Y.; McDowell, William H.

    2017-12-01

    Tropical rivers account for two thirds of global fluxes of terrigenous organic matter to the oceans, yet because of their remote locations relative to most industrialized countries, they are poorly studied compared to temperate and even Arctic rivers. Further, most tropical river research has focused on large rivers like the Amazon or Congo, yet more than half of organic matter fluxes from tropical rivers comes from much smaller rivers. This study focuses on two such rivers in the Luquillo Experimental Forest of Puerto Rico, namely the Rio Mameyes and Rio Icacos, and uses time-series measurements of lignin biomarkers to put them in context with much bigger tropical rivers in the literature. Although lignin concentrations and carbon-normalized yields offer some distinction between mountainous vs. floodplain tropical river reaches, compositional differences appear to offer greater potential, including S:V vs. C:V plots that may capture the poorly-studied influence of palm trees, and (Ad:Al)s vs. (Ad:Al)v plots that may reflect differences in underlying mineralogy and degradation in soils. Even though dissolved and particulate lignin ultimately come from the same vegetation sources, comparison of dissolved and particulate lignin parameters within the two Puerto Rican rivers indicate that the pathways by which they end up in the same parcel of river water are largely decoupled. Across several particulate lignin studies in tropical rivers, mineral composition and concentration appears to exert a strong control on particulate lignin compositions and concentrations. Finally, the time-series nature of this study allows for new ways of analyzing dissolved lignin endmember compositions and degradation within the catchment. Plots of dissolved lignin parameters vs. lignin concentration reveal both the composition of "fresh" DOM that is likely mobilized from organic-rich soil surface layers along with the extent and trajectory of degradation of that signature that is possible

  3. Limnological changes in Dom Helvécio Lake (South-East Brazil: natural and anthropogenic causes

    Directory of Open Access Journals (Sweden)

    PM. Maia-Barbosa

    Full Text Available In order to verify changes in physical, chemical and biological features of Dom Helvécio Lake (South-East Brazil, this study compares previous and recent data obtained from limnological investigations over three decades. Plankton species composition and density together with environmental data from 1978, 1983, and during 1999 to 2006 showed changes driven by seasonal climatic forces or by anthropogenic causes. Changes in diversity are shown as a consequence of alternation of rainy and dry periods and introduction of exotic fish species. Finally, suggestions are made for improving conservation efforts in the area, through planned actions and monitoring programmes.

  4. Factores que afectan la demanda de agua para uso doméstico en México

    Directory of Open Access Journals (Sweden)

    Alejandro Salazar Adams

    2010-01-01

    Full Text Available En el presente estudio se calcula la demanda de agua para uso doméstico en la república mexicana, con bases de datos agregados a escala local. Resultaron significativos factores como la elasticidad precio estimada, de -0.33, y la elasticidad ingreso, de 0.2, entre otros asociados a la demanda, por lo que deben ser considerados en la planeación y administración de los servicios de agua potable en México.

  5. Estratégias multimídia de incentivo à leitura: estudo do caso Dom Casmurro

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    Fátima Cristina Regis Martins de Oliveira

    2015-05-01

    Full Text Available O objetivo deste artigo é apresentar estratégias de recursos multimidiáticos para promover o hábito e o prazer à leitura. Para isso, é feita a análise do caso da obra Dom Casmurro, de Machado de Assis, divulgada em diversos produtos e suportes (mashup de livros, seriados, audiolivro, livroclip, que exploram múltiplas sensorialidades, linguagens e formas de narrativa. Diante da dificuldade do ensino tradicional com o tema, almeja-se atrair os jovens para a leitura da obra original.

  6. Murcutt, Pawson, Lacaton & Vassal: Intenciones y estrategias en la fotografía del espacio doméstico

    OpenAIRE

    Jerez-Abajo, E. (Enrique)

    2016-01-01

    Glenn Murcutt, John Pawson y Anne Lacaton & Jean Philippe Vassal escenifican 3 concepciones diversas de la arquitectura actual. Una parte importante de su trabajo se ha volcado hacia el ámbito doméstico, y concretamente hacia la vivienda unifamiliar. Las casas de campo de Murcutt, de metal y madera, son respetuosas con la naturaleza y simultáneamente vernáculas y contemporáneas gracias a la inclusión de principios energéticos pasivos presentes en la arquitectura popular. Las vi...

  7. Diego Domínguez Caballero y algunas cuestiones nucleares de la filosofía en Panamá

    OpenAIRE

    Rodríguez, Abdiel

    2014-01-01

    En este ensayo, el autor realiza una reseña histórica sobre el trabajo de Diego Domínguez Caballero, renombrado filósofo y docente panameño. Además, se abordal el rol crítico que desempeñó Dominguez en la enseñanza de la filosofía en al educación superior panameña, la coceptualización de la filosofía panaméña y la búsqueda de lo panameño.

  8. Estudio sobre la aplicación de la Ley Contra la Violencia Doméstica.

    OpenAIRE

    Molina Blanco, Leticia

    2015-01-01

    Este trabajo es un estudio, que presenta una óptica de la promulgación legislativa sobre violencia doméstica de un país Latinoamericano, Costa Rica, preocupado por tratar de dar contenido normativo de contención a uno de los males que más afectan a la humanidad: la agresión dentro del hogar. Se trata de una normativa, relativamente joven, que ha encontrado una serie de limitaciones para su buena y correcta aplicación, y encierra situaciones del diario vivir que trascienden los estrados judici...

  9. "Sirvienta", "chica", "doméstica" : Su representación en la construcción del discurso social

    OpenAIRE

    Hovhannessian, M. M; Serna, M. Alcira

    2014-01-01

    El rol de la mujer a principios del S XX se vio modificado por su ingreso definitivo al campo laboral como consecuencia de la industrialización que primero las conduce a las fábricas y que en este período se extiende en la “profesionalización” como mucama. El tema del trabajo, en general, y del ejercido por “la doméstica”, en particular, fue crucial tanto en la vida de las mujeres de las clases populares como de las inmigrantes. Este servicio constituyó “un refugio” para este amplio sector qu...

  10. Acute, fatal Sarcocystis calchasi-associated hepatitis in Roller pigeons (Columba livia f. dom.) at Philadelphia Zoo.

    Science.gov (United States)

    Trupkiewicz, J G; Calero-Bernal, R; Verma, S K; Mowery, J; Davison, S; Habecker, P; Georoff, T A; Ialeggio, D M; Dubey, J P

    2016-01-30

    Four Roller pigeons (Columba livia f. dom.) at the Philadelphia Zoo died suddenly. Necropsy examination revealed macroscopic hepatitis. Microscopically, the predominant lesions were in liver, characterized with necrosis and mixed cell inflammatory response. Sarcocystis calchasi-like schizonts and free merozoites were identified in liver. Transmission electron microscopy confirmed that schizonts were in hepatocytes. A few schizonts were in spleen. PCR using S. calchasi-specific primers confirmed the diagnosis. Neither lesions nor protozoa were found in brain and muscles. This is the first report of acute visceral S. calchasi-associated sarcocystosis in naturally infected avian hosts. Published by Elsevier B.V.

  11. Masculinidades no juizado de violência doméstica e familiar contra a mulher: performances em cena

    OpenAIRE

    Chagas Barboza Brasilino, Jullyane

    2010-01-01

    Como são performadas masculinidades e negociados posicionamentos em audiências de um Juizado de Violência Doméstica e Familiar contra a Mulher? foi a pergunta de pesquisa que orientou este trabalho. O Juizado foi instituído pela Lei 11.340/2006 (Maria da Penha), em cujo texto se destaca que as medidas integradas de prevenção devem ter, entre suas diretrizes, o respeito dos valores éticos e sociais da pessoa e da família, de forma a coibir os papéis estereotipados que legitimem ou exacerbem ...

  12. Etologia, Antropologia e cinema: uma etnografia da violência em Sob o Domínio do Medo

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    Mauricio Rodrigues de Souza

    2009-12-01

    Full Text Available Este artigo aparece como uma tentativa de compreensão do fenômeno da agressão em seus múltiplos aspectos, tarefa para a qual contaremos com os referenciais teóricos advindos da Etologia e da Antropologia Social. Para melhor expressar as idéias aqui expostas utilizaremos o cinema como recurso etnográfico. Neste sentido, destacaremos alguns trechos do filme Sob o Domínio do Medo (1971, os quais serão trabalhados em maiores detalhes.

  13. Implantación de un sistema domótico en el Palacio de Hielo de Itaroa

    OpenAIRE

    Vital García, David

    2010-01-01

    El control de dispositivos ha sido un problema estudiado por el hombre con el objetivo de automatizar ciertas tareas. Se entiende por domótica al conjunto de sistemas capaces de automatizar una vivienda. Para los edificios, el sector maneja la palabra inmótica. La inmótica, aporta servicios de gestión energética, seguridad, bienestar, confort, comunicación. Se podría definir como la integración de la tecnología en el diseño inteligente de un recinto. En este proyecto fin de carrer...

  14. Prediction of dosage-based parameters from the puff dispersion of airborne materials in urban environments using the CFD-RANS methodology

    Science.gov (United States)

    Efthimiou, G. C.; Andronopoulos, S.; Bartzis, J. G.

    2018-02-01

    One of the key issues of recent research on the dispersion inside complex urban environments is the ability to predict dosage-based parameters from the puff release of an airborne material from a point source in the atmospheric boundary layer inside the built-up area. The present work addresses the question of whether the computational fluid dynamics (CFD)-Reynolds-averaged Navier-Stokes (RANS) methodology can be used to predict ensemble-average dosage-based parameters that are related with the puff dispersion. RANS simulations with the ADREA-HF code were, therefore, performed, where a single puff was released in each case. The present method is validated against the data sets from two wind-tunnel experiments. In each experiment, more than 200 puffs were released from which ensemble-averaged dosage-based parameters were calculated and compared to the model's predictions. The performance of the model was evaluated using scatter plots and three validation metrics: fractional bias, normalized mean square error, and factor of two. The model presented a better performance for the temporal parameters (i.e., ensemble-average times of puff arrival, peak, leaving, duration, ascent, and descent) than for the ensemble-average dosage and peak concentration. The majority of the obtained values of validation metrics were inside established acceptance limits. Based on the obtained model performance indices, the CFD-RANS methodology as implemented in the code ADREA-HF is able to predict the ensemble-average temporal quantities related to transient emissions of airborne material in urban areas within the range of the model performance acceptance criteria established in the literature. The CFD-RANS methodology as implemented in the code ADREA-HF is also able to predict the ensemble-average dosage, but the dosage results should be treated with some caution; as in one case, the observed ensemble-average dosage was under-estimated slightly more than the acceptance criteria. Ensemble

  15. Prediction of dosage-based parameters from the puff dispersion of airborne materials in urban environments using the CFD-RANS methodology

    Science.gov (United States)

    Efthimiou, G. C.; Andronopoulos, S.; Bartzis, J. G.

    2017-02-01

    One of the key issues of recent research on the dispersion inside complex urban environments is the ability to predict dosage-based parameters from the puff release of an airborne material from a point source in the atmospheric boundary layer inside the built-up area. The present work addresses the question of whether the computational fluid dynamics (CFD)-Reynolds-averaged Navier-Stokes (RANS) methodology can be used to predict ensemble-average dosage-based parameters that are related with the puff dispersion. RANS simulations with the ADREA-HF code were, therefore, performed, where a single puff was released in each case. The present method is validated against the data sets from two wind-tunnel experiments. In each experiment, more than 200 puffs were released from which ensemble-averaged dosage-based parameters were calculated and compared to the model's predictions. The performance of the model was evaluated using scatter plots and three validation metrics: fractional bias, normalized mean square error, and factor of two. The model presented a better performance for the temporal parameters (i.e., ensemble-average times of puff arrival, peak, leaving, duration, ascent, and descent) than for the ensemble-average dosage and peak concentration. The majority of the obtained values of validation metrics were inside established acceptance limits. Based on the obtained model performance indices, the CFD-RANS methodology as implemented in the code ADREA-HF is able to predict the ensemble-average temporal quantities related to transient emissions of airborne material in urban areas within the range of the model performance acceptance criteria established in the literature. The CFD-RANS methodology as implemented in the code ADREA-HF is also able to predict the ensemble-average dosage, but the dosage results should be treated with some caution; as in one case, the observed ensemble-average dosage was under-estimated slightly more than the acceptance criteria. Ensemble

  16. Enhanced catalytic performance for methane combustion of 3DOM CoFe2O4 by co-loading MnOx and Pd-Pt alloy nanoparticles

    Science.gov (United States)

    Li, Xiangyu; Liu, Yuxi; Deng, Jiguang; Xie, Shaohua; Zhao, Xingtian; Zhang, Yang; Zhang, Kunfeng; Arandiyan, Hamidreza; Guo, Guangsheng; Dai, Hongxing

    2017-05-01

    Three-dimensionally ordered macroporous (3DOM) CoFe2O4, zMnOx/3DOM CoFe2O4 (z = 4.99-12.30 wt%), and yPd-Pt/6.70 wt% MnOx/3DOM CoFe2O4 (y = 0.44-1.81 wt%; Pd/Pt molar ratio = 2.1-2.2) have been prepared using the polymethyl methacrylate microspheres-templating, incipient wetness impregnation, and bubble-assisted polyvinyl alcohol-protected reduction strategies, respectively. All of the samples were characterized by means of various techniques. Catalytic performance of the samples was measured for methane combustion. It is shown that the as-prepared samples exhibited a high-quality 3DOM structure (103 ± 20 nm in pore size) and a surface area of 19-28 m2/g, and the noble metal or alloy nanoparticles (NPs) with a size of 2.2-3.0 nm were uniformly dispersed on the macropore wall surface of 3DOM CoFe2O4. The loading of MnOx on CoFe2O4 gave rise to a slight increase in activity, however, the dispersion of Pd-Pt NPs on 6.70MnOx/3DOM CoFe2O4 significantly enhanced the catalytic performance, with the 1.81Pd2.1Pt/6.70MnOx/3DOM CoFe2O4 sample showing the highest activity (T10% = 255 °C, T50% = 301 °C, and T90% = 372 °C at a space velocity of 20,000 mL/(g h)). We believe that the excellent catalytic activity of 1.81Pd2.1Pt/6.70MnOx/3DOM CoFe2O4 was related to its well-dispersed Pd-Pt alloy NPs, high adsorbed oxygen species concentration, good low-temperature reducibility, and strong interaction between MnOx or Pd-Pt NPs and 3DOM CoFe2O4.

  17. Diseño e implementación de un sistema domótico de radiofrecuencia para brindar gestión de networking, seguridad y confort usando los protocolos z-wave y zigbee

    OpenAIRE

    Intriago Velasquez, Gabriel Andres

    2015-01-01

    El presente proyecto desarrolla e implementa un sistema domótico de radiofrecuencia. De manera general, se escogió la domótica de radiofrecuencia, ya que es menos costosa y más fácil de implementar que la domótica cableada, a parte, que en los últimos años ha ganado confiabilidad de operación y comunicación entre sus dispositivos. Los protocolos de radiofrecuencia usados en el sistema domótico fueron Z-Wave y Zigbee, debido a su bajo consumo de potencia, funcionamiento de red en modo de malla...

  18. Aborto provocado e violência doméstica entre mulheres atendidas em uma maternidade pública de Salvador-BA

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    Normélia Maria Freire Diniz

    2011-12-01

    Full Text Available Estudo quantitativo, com o objetivo de estudar a violência doméstica em mulheres em situação de aborto provocado. Foram entrevistas 147 mulheres internadas por aborto provocado numa maternidade pública, na cidade de Salvador-BA. Os sujeitos foram, na maioria, mulheres jovens, negras, com baixa escolaridade, dependentes economicamente dos cônjuges, que vivenciam violência psicológica, física e sexual cometida pelos cônjuges. Quase metade das mulheres vivenciou violência doméstica durante a gravidez atual, sendo este o motivo do aborto para 67% delas. Conclui-se que existe uma associação entre a vivência de violência doméstica e o aborto provocado. Isso repercute na saúde mental das mulheres, que desenvolvem sintomas do transtorno de estresse pós-traumático. Necessita-se, portanto, de um olhar por parte dos profissionais de saúde de modo a identificar a violência doméstica enquanto agravo e associá-la ao aborto provocado, o que requer transformação no modelo de formação, incorporando a violência doméstica como objeto da saúde.

  19. Hurto, consumo y género en el servicio doméstico (Mar del Plata, 1950-1980

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    Inés Pérez

    2016-12-01

    Full Text Available Las ciencias sociales han discutido largamente sobre el papel del intercambio de bienes, valores culturales y pautas de consumo en el marco del servicio doméstico. En ese contexto, los hurtos de las trabajadoras domésticas a sus empleadores han sido leídos como parte de formas de resistencia hacia las desigualdades experimentadas en el marco de su trabajo. Retomando esos aportes, este artículo se centra en los objetos hurtados, muchas veces de escaso valor monetario pero de un alto valor simbólico, asociados a la feminidad. A partir del análisis de diecinueve expedientes de hurto, se sostiene que el hecho de que este tipo de objetos estuvieran involucrados de manera recurrente en casos de robo responde a una forma particular de definir la justicia, anclada en el acceso a ciertos bienes. La centralidad de estos bienes muestra, además, la circulación de distintos modelos de feminidad entre trabajadoras y empleadoras.

  20. Terminologia da Enfermagem caracterizadora da violência doméstica contra crianças e adolescentes

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    Lêda Maria Albuquerque

    2015-06-01

    Full Text Available RESUMOObjetivo:identificar termos relacionados à prática de enfermagem direcionada à criança e ao adolescente em situação de violência doméstica.Método:pesquisa descritiva bibliográfica, que selecionou 40 artigos na base da Biblioteca Virtual em Saúde, no tema da violência doméstica contra a criança e o adolescente, suas manifestações, causas e consequências, articulado com as práticas de enfermagem para enfrentamento e prevenção; e extraiu termos com uso de ferramenta computacional.Resultados:Foram extraídos 17.365 termos que após a normalização e adequação, resultou numa lista de 915 termos.Conclusão:Os termos selecionados focalizam o nexo biopsíquico individual e a face histórica do fenômeno foi, em parte, identificada em termos de menor frequência de aparição nos artigos, explicitando a contradição entre a lógica formal de identificação dos termos e a lógica dialética que reconhece as raízes históricas e a dinamicidade dos fenômenos.

  1. Early UV emission from disc-originated matter (DOM) in Type Ia supernovae in the double-degenerate scenario

    Science.gov (United States)

    Levanon, Naveh; Soker, Noam

    2017-09-01

    We show that the blue and UV excess emission in the first few days of some Type Ia supernovae (SNe Ia) can be accounted in the double-degenerate (DD) scenario by the collision of the SN ejecta with circumstellar matter that was blown by the accretion disc formed during the merger process of the two white dwarfs (WDs). We assume that in cases of excess early light, the disc blows the circumstellar matter, that we term disc-originated matter (DOM), hours to days before explosion. To perform our analysis, we first provide a model-based definition for early excess light, replacing the definition of excess light relative to a power-law fit to the rising luminosity. We then examine the light curves of the SNe Ia iPTF14atg and SN 2012cg, and find that the collision of the ejecta with a DOM in the frame of the DD scenario can account for their early excess emission. Thus, early excess light does not necessarily imply the presence of a stellar companion in the frame of the single-degenerate scenario. Our findings further increase the variety of phenomena that the DD scenario can account for, and emphasize the need to consider all different SN Ia scenarios when interpreting observations.

  2. Estudo do tempo de excreção renal pela cintilografia em felinos domésticos

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    Georgea Bignardi Jarretta

    2010-02-01

    Full Text Available Na rotina clínica de felinos domésticos, algumas modalidades de diagnóstico por imagem, como a ultrassonografia, radiografia simples e urografia excretora, já são amplamente utilizadas. A cintilografia é uma técnica não invasiva, capaz de oferecer informações funcionais de rins individualmente, porém é considerada uma modalidade menos usual. O objetivo deste estudo foi verificar o tempo de excreção renal de felinos domésticos por meio da cintilografia, em animais com parâmetros ultrassonográficos e radiográficos dentro dos limites da normalidade. Foram utilizados 15 animais, nove machos e seis fêmeas, e estes foram divididos em grupos de animais não submetidos à anestesia e anestesiados. Foi estabelecido o tempo para o radiofármaco obter acúmulo máximo em cada um dos rins e o tempo para este acúmulo máximo ser reduzido à metade. Não houve diferença estatística entre os valores dos animais não-anestesiados e anestesiados, nem entre os rins esquerdo e direito, tampouco entre machos e fêmeas.

  3. Desarrollo de la justicia restaurativa en el ámbito de la violencia doméstica

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    Karla Annett Cynthia Sáenz López

    2016-08-01

    Full Text Available El desarrollo que ha tomado la justicia restaurativa en los últimos años es gracias a los beneficios comprobables de ofrecer una alternativa de resolución orientada a la reparación, desjudizialización y dialogo entre los directamente involucrados en el conflicto. A pesar de que la mayor parte de dicha aplicación se ha dado sobre todo dentro de los procesos en el ámbito de la justicia penal, especialmente en los sistemas de justicia penal para adolescentes en diferentes países, este tipo de justicia ha logrado permear su filosofía a otras problemáticas sociales como es la violencia doméstica o contra la mujer. El contar con una visión internacional sobre los procesos de Justicia Restaurativa aplicados en otros países del mundo a casos de violencia doméstica o mujeres víctimas de violencia, brinda la oportunidad a nuestro país de contar con un marco de referencia para optimizar los esfuerzos enfocados a proporcionar a las víctimas, victimarios y comunidad, procesos de impartición de justicia de calidad y sobre todo enfocados a buscar una restauración integral para todos.

  4. Poderosa ignorancia: celos y pretensión de verdad en Dom Casmurro de Machado de Assis

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    Rubén A. Sánchez-Godoy

    2014-01-01

    Full Text Available Este ensayo explora cómo las sospechas no comprobadas del protagonista de Dom Casmurro se articulan en un monólogo que pretende probar la infidelidad de su amada. Con base en el concepto de ideología de Žižek, proponemos que esta articulación es posible a partir de la construcción de una prueba que permite al narrador producir a su amada como objeto de deseo ambiguo, fascinante y poco confiable a la vez. Al reconstruir literariamente esta prueba, que convierte la incertidumbre y la sospecha en formas de empoderamiento epistemológico y moral, Machado expone e ironiza una perspectiva masculina que busca proteger privilegios de género en una sociedad con creciente movilidad femenina. This essay explores the way in which the unproven suspicions of the main character of Dom Casmurro become a monologue that aims to prove the infidelity of his beloved. Using Žižek’s concept of ideology, I propose that this monologue is possible on the basis of the elaboration of an argument that allows to the narrator to produce his object of desire as an ambiguous one, fascinating and unreliable at the same time. Through the literary reconstruction of this argument, that transforms incertitude and suspicion in possibilities of epistemological and moral empowering, Machado discusses and ironizes a masculine perspective that tries to maintain its gender related privileges in a society with increasing feminine mobility.

  5. El reparto desigual del trabajo doméstico y sus efectos sobre la estabilidad de los proyectos conyugales

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    GERARDO MEIL LANDWERLIN

    2005-01-01

    Full Text Available El cambio familiar ha dado lugar a la emergencia de un "nuevo pacto conyugal" caracterizado por la negociabilidad de los términos de la convivencia, tanto en la forma en la que se inicia como en la que se desarrolla y eventualmente puede terminarse. Sobre la base de una encuesta realizada en la Comunidad de Madrid en 2003 entre las que hemos denominado "nuevas familias", se analizan los potenciales efectos que el reparto desigual del trabajo doméstico y del cuidado de los niños tiene sobre la satisfacción con la dinámica de pareja y con el riesgo de ruptura del proyecto de vida en común. Aplicando un análisis de regresión logística, la razón de probabilidades de haber pensado así como de haber hablado seriamente de la ruptura del proyecto de vida en común está condicionada, entre otras variables, tanto por los términos del reparto del trabajo doméstico como por la satisfacción con los términos del mismo y la potencial conflictividad que puede generar. A menor desigualdad en el reparto, mayor satisfacción con el mismo, y a menor conflictividad, menor riesgo de ruptura, controlados los efectos de la conflictividad general de la pareja.

  6. Triangular público, doméstico y privado, o ¿cómo negociar en pareja?

    Directory of Open Access Journals (Sweden)

    MARTA GUTIÉRREZ SASTRE

    2002-01-01

    Full Text Available Se afronta el tema de las posibilidades de negociar e iniciar cambios en la pareja, cuestionando los principios de la negociación liberal e introduciendo los matices que nos permitan establecer el tipo de intercambio que se puede producir entre dos personas situadas en posiciones distintas. Se introduce el término de lo privado, que lejos de connotaciones intimistas, se entiende como la interacción que en lo interpersonal establece la pareja en relación al medio social, económico y político. La triangulación de las facetas pública, doméstica y privada constituye la clave para entender las posibilidades de negociar dentro de la pareja. Se advierte la omnipresencia de la faceta pública y el declive de la doméstica en favor de la privada. Se establece, por úlitmo, una tipología de cuatro tipos de parejas en función de cómo interactúen los tres ámbitos mencionados.

  7. A stable chemical SUMO1-Ubc9 conjugate specifically binds as a thioester mimic to the RanBP2-E3 ligase complex.

    Science.gov (United States)

    Sommer, Stefanie; Ritterhoff, Tobias; Melchior, Frauke; Mootz, Henning D

    2015-05-26

    Ubiquitin and ubiquitin-like (Ubl) modifiers such as SUMO are conjugated to substrate proteins by E1, E2, and E3 enzymes. In the presence of an E3 ligase, the E2∼Ubl thioester intermediate becomes highly activated and is prone to chemical decomposition, thus making biochemical and structural studies difficult. Here we explored a stable chemical conjugate of the E2 enzyme from the SUMO pathway, Ubc9, with its modifier SUMO1 as a structural analogue of the Ubc9∼SUMO1 thioester intermediate, by introducing a triazole linkage by biorthogonal click chemistry. The chemical conjugate proved stable against proteolytic cleavage, in contrast to a Ubc9-SUMO1 isopeptide analogue obtained by auto-SUMOylation. Triazole-linked Ubc9-SUMO1 bound specifically to the preassembled E3 ligase complex RanBP2/RanGAP1*SUMO1/Ubc9, thus suggesting that it is a suitable thioester mimic. We anticipate interesting prospects for its use as a research tool to study protein complexes involving E2 and E3 enzymes. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. Protocolo de evaluación de niños y adolescentes víctimas de la violencia doméstica

    OpenAIRE

    Olaya Guzmán, Beatriz

    2008-01-01

    Se sintetizan las áreas principales de evaluación psicológica en niños y adolescentes expuestos a violencia doméstica. Las características de la situación vivida (violencia doméstica), los efectos de la misma sobre la salud mental y el funcionamiento cotidiano de los niños y adolescentes y las variables mediadoras de carácter individual, familiar y social son objeto de atención en el proceso de evaluación. Se remarca la importancia de considerar a los niños expuestos a violencia doméstica en ...

  9. Controle de vida, interseccionalidade e política de empoderamento: as organizações políticas das trabalhadoras domésticas no Brasil

    Directory of Open Access Journals (Sweden)

    Joaze Bernardino Costa

    2013-12-01

    Full Text Available Motivado pelas recentes discussões legais em torno do trabalho doméstico no Brasil, este artigo propõe-se destacar o protagonismo das organizações políticas das trabalhadoras domésticas na conquista dos direitos da categoria profissional. Baseado em entrevistas realizadas com trabalhadoras domésticas sindicalizadas em diversas cidades brasileiras, o artigo estrutura seu argumento a partir do conceito de interseccionalidade, demonstrando como, ao longo dos últimos 80 anos, as organizações políticas dessas trabalhadoras têm se articulado com o movimento classista-sindical, negro e feminista, o que tem sido fundamental para desenvolver uma política de empoderamento e de autocontrole da vida.

  10. Bioavailability and radiocarbon age of fluvial dissolved organic matter (DOM) from a northern peatland-dominated catchment: effect of land-use change

    DEFF Research Database (Denmark)

    Hulatt, C.J.; Kaartokallio, H.; Asmala, E.

    2014-01-01

    The radiocarbon age and biodegradability of dissolved organic matter (DOM) from a northern peat-dominated river system was studied and the effects of land-use were compared. Samples were obtained from streams and ditches comprising sub-catchments of the Kiiminki River, Northern Finland. Sample...... identified release of modern (mean 6-13 year old) DOM from natural sites, and material aged up to 1,553 years from disturbed sites. The proportion of biodegradable DOC ranged from 4.1 to 17.9 %, and bacterial DOC removal was modelled using twin-pool and reactivity-continuum (beta distribution) approaches....... Bacterial growth efficiency ranged from 0.11 to 0.26 between areas of different land use, and these relatively low values reflect the humic-rich DOM released from boreal peatland. Despite the range of land-use types studied, including intensive peatland excavation areas, there was no detectable relationship...

  11. Influence of DOM and redox potential on the leaching of As and Cr from coal fly ash

    Science.gov (United States)

    Deonarine, A.; Kolker, A.; Huggins, F.; Foster, A. L.

    2012-12-01

    Coal ash, a byproduct of coal-fired power plants, contains toxic trace elements such as arsenic (As) and chromium (Cr). Coal ash has recently been scrutinized as a potential source of toxic trace elements to aquatic systems and potable water sources, and the legislation pertinent to coal ash management is currently under revision. Coal ash is currently stored in surface impoundments and landfills that are poorly regulated and at risk of failure. Impoundment failure can result in the mobilization of coal ash and leachates into aquatic systems and potable water-sources. The current understanding of the environmental fate (i.e., transformation, toxicity and mobility) of As and Cr in coal ash is largely limited to leaching protocols that are not environmentally relevant, as they exclude parameters such as redox potential and dissolved organic matter (DOM) that are prevalent in aquatic systems. Furthermore, the relationship between coal-ash particle size and the speciation and leaching behavior of As and Cr has not been well investigated. The size of host particles may influence the speciation and coordination environment of trace elements, and may be a critical factor in the leaching/dissolution behavior of As and Cr from coal ash into solution. In this study, coal ash samples from three different coal-fired power plants using different coal sources and different combustion processes were segregated into size fractions (fractions were examined using synchrotron x-ray absorption spectroscopy (XANES/ EXAFS) to determine whether there were any differences in As and Cr concentration and speciation/coordination environment as a function of particle size. Coal-ash size fractions were also exposed to a buffered solution (pH ~7) with varying DOM concentration (1 to 30 mg/L) and redox potential (reducing, oxic). Dissolved concentrations of As and Cr were quantified over time to determine how DOM and redox potential influence the leaching of As and Cr from coal ash into the

  12. The pain threshold of high-threshold mechanosensitive receptors subsequent to maximal eccentric exercise is a potential marker in the prediction of DOMS associated impairment

    Science.gov (United States)

    Simon, Perikles; König, Matthias; Vogt, Lutz; Banzer, Winfried

    2017-01-01

    Background Delayed-onset muscle soreness (DOMS) refers to dull pain and discomfort in people after participating in exercise, sport or recreational physical activities. The aim of this study was to detect underlying mechanical thresholds in an experimental model of DOMS. Methods Randomised study to detect mechanical pain thresholds in a randomised order following experimentally induced DOMS of the non-dominant arm in healthy participants. Main outcome was the detection of the pressure pain threshold (PPT), secondary thresholds included mechanical detection (MDT) and pain thresholds (MPT), pain intensity, pain perceptions and the maximum isometric voluntary force (MIVF). Results Twenty volunteers (9 female and 11 male, age 25.2 ± 3.2 years, weight 70.5 ± 10.8 kg, height 177.4 ± 9.4 cm) participated in the study. DOMS reduced the PPT (at baseline 5.9 ± 0.4 kg/cm2) by a maximum of 1.5 ± 1.4 kg/cm2 (-24%) at 48 hours (p < 0.001). This correlated with the decrease in MIVF (r = -0.48, p = 0.033). Whereas subjective pain was an indicator of the early 48 hours, the PPT was still present after 72 hours (r = 0.48, p = 0.036). Other mechanical thresholds altered significantly due to DOMS, but did show no clinically or physiologically remarkable changes. Conclusions Functional impairment following DOMS seems related to the increased excitability of high-threshold mechanosensitive nociceptors. The PPT was the most valid mechanical threshold to quantify the extent of dysfunction. Thus PPT rather than pain intensity should be considered a possible marker indicating the athletes’ potential risk of injury. PMID:28985238

  13. The Upside to Hg-DOM Associations for Water Quality: Removal of Hg from Solution Using Coagulaion with Metal-Based Salts

    Science.gov (United States)

    Henneberry, Y.; Kraus, T. E.; Fleck, J.; Krabbenhoft, D. P.; Horwath, W. R.

    2011-12-01

    This study assessed the potential use of metal-based coagulants to remove dissolved mercury (Hg) from natural waters and provides information regarding the importance of Hg associations with the dissolved organic matter (DOM) fraction and metal hydroxides. Previous research indicated coagulants were not effective at removing Hg from solution; however those studies used high concentrations of Hg, which did not reflect naturally occurring concentrations of Hg. Filtered water collected from an agricultural drain in the Sacramento-San Joaquin Delta (Delta) was treated with three industrial-grade coagulants (ferric chloride, ferric sulfate, and polyaluminum chloride) to determine their efficacy in removing both inroganic (IHg) and methylmercury (MeHg) from the water column. The Delta suffers from elevated surface water Hg concentrations and as a result is listed as an imparied water body. Coagulants removed up to 85% of DOM from solution. In the absence of DOM, all three coagulants released IHg into solution, however in the presence of DOM the coagulants removed up to 97% of IHg and 80% of MeHg. Results suggest that the removal of Hg is mediated by DOM-coagulant interactions. There was a preferential association of IHg with the more aromatic, higher molecular weight fraction of DOM but no such relationship was found for MeHg. This study offers new fundamental insights regarding large-scale removal of Hg at environmentally relevant concentrations. Research using isotopically labeled Hg is providing insight into whether coagulation can remove recently added Hg (e.g. atmospheric deposition) from solution and whether once formed, the floc can remove additional Hg from the water column.

  14. The pain threshold of high-threshold mechanosensitive receptors subsequent to maximal eccentric exercise is a potential marker in the prediction of DOMS associated impairment.

    Directory of Open Access Journals (Sweden)

    Johannes Fleckenstein

    Full Text Available Delayed-onset muscle soreness (DOMS refers to dull pain and discomfort in people after participating in exercise, sport or recreational physical activities. The aim of this study was to detect underlying mechanical thresholds in an experimental model of DOMS.Randomised study to detect mechanical pain thresholds in a randomised order following experimentally induced DOMS of the non-dominant arm in healthy participants. Main outcome was the detection of the pressure pain threshold (PPT, secondary thresholds included mechanical detection (MDT and pain thresholds (MPT, pain intensity, pain perceptions and the maximum isometric voluntary force (MIVF.Twenty volunteers (9 female and 11 male, age 25.2 ± 3.2 years, weight 70.5 ± 10.8 kg, height 177.4 ± 9.4 cm participated in the study. DOMS reduced the PPT (at baseline 5.9 ± 0.4 kg/cm2 by a maximum of 1.5 ± 1.4 kg/cm2 (-24% at 48 hours (p < 0.001. This correlated with the decrease in MIVF (r = -0.48, p = 0.033. Whereas subjective pain was an indicator of the early 48 hours, the PPT was still present after 72 hours (r = 0.48, p = 0.036. Other mechanical thresholds altered significantly due to DOMS, but did show no clinically or physiologically remarkable changes.Functional impairment following DOMS seems related to the increased excitability of high-threshold mechanosensitive nociceptors. The PPT was the most valid mechanical threshold to quantify the extent of dysfunction. Thus PPT rather than pain intensity should be considered a possible marker indicating the athletes' potential risk of injury.

  15. Differences in DOM of rewetted and natural peatlands - Results from high-field FT-ICR-MS and bulk optical parameters.

    Science.gov (United States)

    Herzsprung, Peter; Osterloh, Katja; von Tümpling, Wolf; Harir, Mourad; Hertkorn, Norbert; Schmitt-Kopplin, Philippe; Meissner, Ralph; Bernsdorf, Sabine; Friese, Kurt

    2017-05-15

    Peatlands can be a potential source of dissolved organic matter (DOM) in fresh water catchment areas. The quantity and quality of DOM can differ between pristine, degraded and rewetted peatlands. Due to the large scale and continuing losses of peatlands, their conservation and restoration has been increasingly emphasized. Mostly rewetting measures are required to improve the hydrology of damaged peatlands, which is a precondition for the resettlement of peat-forming plant species. Thus, in term of DOM, there is a special need to understand how rewetting measures affect DOM characteristics and concentrations. To estimate the potential leaching of humic substances from rewetted areas two natural sites were compared with four artificially rewetted sites in a peatland area of the Harz Mountains National Park, Germany. This was done with regards to DOM quality by combining the results from Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR-MS, measured at one time in Spring) and excitation-emission-matrix fluorescence spectroscopy (EEMF, measured monthly for the period of one year). The DOM quality was significantly less variable in the pristine peatland soil water compared to the rewetted peatland soil waters, from both a spatial and a seasonal perspective. The soil water from the rewetted peatland sites showed a higher degree of humification compared to pristine peatland. DOC concentration was mostly consistent in the pristine peatland over the year. The rewetted peatlands showed higher DOC levels in Summer months and lower DOC in Winter months compared to the pristine peatland. It can be concluded that the rewetting of peatlands is coupled with high concentrations of DOC in soil water and its quality is highly aromatic (as reflected by the observed values from the humification index) during times with elevated temperature. The results may have a significant input for dynamic catchment area studies with regards to rewetting peatland sites. Copyright

  16. A new approach for evaluating transformations of dissolved organic matter (DOM) via high-resolution mass spectrometry and relating it to bacterial activity.

    Science.gov (United States)

    Kamjunke, Norbert; von Tümpling, Wolf; Hertkorn, Norbert; Harir, Mourad; Schmitt-Kopplin, Philippe; Norf, Helge; Weitere, Markus; Herzsprung, Peter

    2017-10-15

    Streams are important sites of transformation of dissolved organic matter (DOM). The molecular characterization of DOM-quality changes requires sophisticated analytical evaluation techniques. The goal of our study was to link molecular DOM transformation with bacterial activity. We measured the degradation of leaf leachate over a gradient of bacterial production obtained by different rates of percolation of sediments in seven experimental flumes on five sampling dates. We developed a new strategy for evaluating molecular formula data sets obtained by ultra-high resolution Fourier transform ion cyclotron resonance mass spectrometry (FTICR MS), in which the time-dependent change of component abundance was fitted by a linear regression model after normalization of mass peak intensities. All components were categorized by calculating the slope (change of percent intensity per day) in each of the seven flumes. These slopes were then related to cumulative bacterial production. The concentration of DOM decreased quickly in all flumes. Bacterial activity was higher in flumes with percolated sediment than in those without percolation, whereas plankton bacterial activity was higher in flumes without percolation or without sediment. There were no differences in molecular-DOM characteristics between flumes, but there were distinct changes over time. Positive slopes, i.e. increasing intensities over time, were found for small molecules (MW < 450 Da) and high O/C ratios, whereas decreasing intensities were observed less often and only for large molecules and low O/C ratios. The positive slopes of produced components showed a positive relationship to bacterial production for small and for oxygen-rich components. The negative slopes of degraded components were negatively related to bacterial production for large and for oxygen-deficient molecules. Overall, the approach provided new insights into the transformation of specific molecular DOM components. Copyright © 2017 Elsevier

  17. El trabajo reproductivo o doméstico Reproductiva or domestic work

    Directory of Open Access Journals (Sweden)

    Isabel Larrañaga

    2004-05-01

    Full Text Available El objetivo de este artículo es describir la evolución del trabajo reproductivo y analizar los factores relacionados con su reparto. Para ello, se han analizado los datos de las Encuestas sobre Usos del Tiempo (1993, 1996, 2001 del Instituto de la Mujer y las encuestas autonómicas de Andalucía, País Vasco, Madrid y la Región Metropolitana de Barcelona. En el período 1993-2001, en España los hombres aumentaron su dedicación al trabajo doméstico en un 35%, mientras que las mujeres la redujeron en casi un 5%. En 2001 la dedicación de las mujeres duplica la de los hombres (7,22 y 3,1 h diarias, respectivamente, aunque las diferencias son menores entre los más jóvenes. La formación del hogar y su aumento de tamaño incrementan las exigencias familiares a las mujeres, acentuándose las diferencias de género. No obstante, tener empleo y un mayor nivel de estudios o ingresos reduce la dedicación femenina y las diferencias de género. El trabajo reproductivo sigue siendo una responsabilidad eminentemente femenina, a pesar del aumento en la participación de los hombres. Los cambios legales, sociales y culturales de los últimos años no han conseguido eliminar el modelo tradicional de adscripción del trabajo reproductivo.The objective of this article is to describe the evolution of reproductive work and to analyse those factors related to its distribution. The analysis has been based on data from various Time-use Surveys (Women Institute 1993, 1996, 2001 as well as on data from different regional surveys: Andalusia, the Basque Country, Madrid and the metropolitan area of Barcelona. In the period 1993-2001, the amount of time devoted by men to housekeeping in Spain increased by 35% while women's time declined by 5%. Yet, in 2001 women's dedication to housekeeping was twice that of men's (7.2 vs 3.1 h daily. However, the imbalance in sharing of housework declined among younger people. Union formation and growing family size increase women

  18. Disseny de la instal·lació domòtica i elèctrica d'una vivenda unifamiliar

    OpenAIRE

    Busqué Trabalón, Joan

    2010-01-01

    En el present projecte es fa el disseny de la instal·lació domòtica d’una casa unifamiliar, tractant d’assegurar en tot moment els quatre grans eixos que ofereix la domòtica: la seguretat (en front de les intrusions i les alarmes tècniques), el confort (en aspectes de climatització, d’il·luminació, en aspectes quotidians diversos, etc.), l’estalvi econòmic (amb la facturació del consum d’aigua per la recollida de les aigües pluvials i el seu posterior aprofitament, amb la regul...

  19. Violência doméstica e risco para problemas de saúde mental em crianças e adolescentes

    OpenAIRE

    Hildebrand, Natália Amaral; Celeri, Eloisa Helena Rubello Valler; Morcillo, André Moreno; Zanolli, Maria de Lurdes

    2015-01-01

    A literatura demonstra que sofrer violência doméstica na infância e juventude é um risco para o desenvolvimento das psicopatologias. Este estudo utilizou o Strenghts and Difficulties Questionnarie (SDQ) e encontrou prevalência de 65,5% de possibilidades de problemas de saúde mental em crianças e adolescentes (4-16 anos), vítimas de violência doméstica, acompanhados em Serviços de Referência, todos residentes em um município brasileiro. O resultado encontrado foi considerado elevado, se compar...

  20. Diseño de un prototipo para el ensayo de domóticas con tecnología EIB

    OpenAIRE

    Giménez Sánchez, Miguel Ángel

    2009-01-01

    [ESP]Actualmente la domótica esta experimentando un gran desarrollo y se está introduciendo cada vez mas en la vida cotidiana, y su proyección es indudable. Por lo tanto su estudio y comprensión es cada día más importante. Con este proyecto se pretende obtener una herramienta útil para el estudio de una instalación domótica bajo el sistema EIB-KNX, mediante un prototipo de instalación con el que se podrá interactuar y realizar todas las conexiones y programaciones necesarias. La idea es re...

  1. Aptidão aeróbia e amplitude dos domínios de intensidade de exercício no ciclismo

    Directory of Open Access Journals (Sweden)

    Renato Aparecido Corrêa Caritá

    2013-08-01

    Full Text Available INTRODUÇÃO: A determinação dos domínios de intensidade de exercício tem importantes implicações na prescrição do treino aeróbio e na elaboração de delineamentos experimentais. OBJETIVO: Analisar os efeitos do nível de aptidão aeróbia sobre a amplitude dos domínios de intensidade de exercício durante o ciclismo. MÉTODOS: Doze ciclistas (CIC, 11 corredores (COR e oito indivíduos não treinados (NT foram submetidos aos seguintes protocolos em diferentes dias: 1 teste progressivo para determinação do limiar de lactato (LL, consumo máximo de oxigênio (VO2máx e sua respectiva intensidade (IVO2máx; 2 três testes de carga constante até a exaustão a 95, 100 e 110% IVO2máx para a determinação da potência crítica (PC; 3 testes até a exaustão para determinar a intensidade superior do domínio severo (Isup. As amplitudes dos domínios (moderado pesado severo < Isup foram expressas como percentual da Isup (VO2. RESULTADOS: A amplitude do domínio moderado foi similar entre CIC (52 ± 8% e COR (47 ± 4% e significantemente maior no CIC em relação ao NT (41 ± 7%. O domínio pesado foi significantemente menor no CIC (17 ± 6% em relação ao COR (27 ± 6% e NT (27 ± 9%. Em relação ao domínio severo não foram encontradas diferenças significantes entre os CIC (31 ± 7%, COR (26 ± 5% e NT (31 ± 7%. CONCLUSÃO: O domínio pesado de exercício é mais sensível a mudanças determinadas pelo nível de aptidão aeróbia, existindo a necessidade de que se atenda ao princípio da especificidade do movimento, quando se pretende obter um elevado grau de adaptação fisiológica.

  2. Violência, ética e direito: implicações para o reconhecimento da violência doméstica contra crianças

    OpenAIRE

    Rosa,Edinete Maria; Tassara,Eda Terezinha de Oliveira

    2004-01-01

    Os conceitos de violência desenvolvidos por Hannah Arendt e Marilena Chauí levam-nos a refletir a respeito da violência doméstica contra crianças, ampliando seu significado e possibilitando questionar determinados sentidos a ela atribuídos. A justificativa e a aplicação do Direito quanto ao que caracteriza um ato violento não conseguem abarcar situações como a violência doméstica e a violência institucional. Essas modalidades de violência parecem manter estreita ligação, pois ambas são coloca...

  3. Distintas o iguales: las diferencias en el trabajo doméstico de las parejas de doble ingreso entre las uniones libres y los matrimonios

    OpenAIRE

    Landy Sánchez Peña; Julieta Pérez Amador

    2016-01-01

    La brecha de género en el trabajo doméstico ha sido ampliamente estudiada en México, mostrando gradientes por nivel socioeconómico y diferencias asociadas a la participación de las mujeres en el trabajo extradoméstico. En este artículo indagamos en qué medida ambos procesos dan forma al reparto del trabajo doméstico entre parejas de doble provee - dor que difieren por tipo de unión. Basamos el análisis empírico en la ENIGH 2010 utilizando modelos de regresión. Nuestros resultados sugieren...

  4. Guía técnica de prevención de riesgos laborales para trabajos en domótica e inmótica

    OpenAIRE

    Tommasino Juncal, Florencia

    2011-01-01

    La normalización del sector de la domótica no ha hecho más que comenzar y existen diversas iniciativas que esperan ver la luz en los próximos años, en forma de normas que faciliten la interoperabilidad entre sistemas y sobre todo, ayuden a extender la información necesaria entre todos los agentes implicados para que el sector comience a asentarse. Para llegar a la concepción de una Guía Técnica en Prevención de Riesgos Laborales para Trabajos en Domótica e ...

  5. Significados de cuidado para crianças e adolescentes vítimas da violência doméstica

    OpenAIRE

    Alcione Leite da Silva; Cristina Vogel; Mirela Schmidt Virgílio

    2001-01-01

    Trata-se de um estudo fenomenológico hermenêutico, que teve como objetivo desvelar os significados de cuidado a partir da experiencia vivida por crianças e adolescentes vítimas da violencia doméstica. Foi desenvolvido em duas Casas-Lares, em Florianópolis, que funcionam em regime de abrigo temporário e excepcional, para crianças e adolescentes do sexo masculino e feminino vítimas da violencia doméstica. As descrições, obtidas nas respostas e desenhos de dezoito crianças e adolescentes do sexo...

  6. Impactos de la violencia doméstica en sociedades tradicionales: La muerte de Antonia Isabel Sánchez, quince años después

    Directory of Open Access Journals (Sweden)

    Tomás A. Mantecón Movellán

    2013-12-01

    Full Text Available Considerando la historiografía sobre las doctrinas que justificaban la construcción de una estructura de poder y autoridad dentro del espacio doméstico en la Europa de los siglos de la Edad Moderna, este artículo profundiza en el análisis de los valores sobre los que se explicaba la producción de violencia doméstica, así como sus concreciones, y evalúa los enfoques para conocer sus impactos en las sociedades tradicionales, enfatizando el aporte que ha significa-do la microhistoria en este campo de investigación.

  7. The effect of d-lysergic acid diethylamide (LSD), 2,5-dimethoxy-4-methylamphetamine (DOM), pentobarbital and methaqualone on punished responding in control and 5,7-dihydroxytryptamine-treated rats.

    Science.gov (United States)

    Commissaris, R L; Lyness, W H; Rech, R H

    1981-05-01

    The purpose of the present study was to determine the role of central 5-hydroxytryptamine (5-HT) neuronal systems in the effects of d-lysergic acid diethylamide (LSD), 2,5-methoxy-4-methylamphetamine (DOM), pentobarbital (PB) and methaqualone (MQ) on punished responding in rats. Water-deprived rats were trained to drink from a tube that was electrified at intervals (variable interval 21 sec; 0.03 mA current intensity), electrification being signalled by a tone. In daily 10-min control sessions, these animals accepted a relatively constant number of shocks; water consumption was also quite stable. At maximally effective doses PB, and to a lesser extent MQ, produced large (400-600 percent of control) increases in punished responding with little decrease in water intake. Higher doses of these agents produced a significant depression of unpunished responding (water intake). The hallucinogens, on the other hand, produced only moderate (125-175 percent of control) increases in the number of shock received, yet a similar depression of unpunished responding. Selective destruction of 5-HT neurons by intracerebroventricular administration of the neurotoxin 5,7-dihydroxytryptamine per se produced little change in the number of shocks received or water consumed in controls sessions. This destruction of 5-HT neurons failed to alter the effects of PB or MQ on punished or unpunished responding. The increase in punished responding produced by the hallucinogens, however, was blocked by this destruction of 5-HT neurons. Furthermore, the capacity of the hallucinogens to decrease water intake was significantly potentiated by the neurotoxin pretreatment. These data demonstrate that the effects of the hallucinogens LSD and DOM on conditioned suppression are quite different from those of PB and MQ, and that this difference may be due to the extent of 5-HT involvement in the effects of these agents.

  8. Exploiting Hidden Layer Responses of Deep Neural Networks for Language Recognition

    Science.gov (United States)

    2016-09-08

    American Spanish, Brazilian Portuguese All the experimental results shown in this paper are per- formed on primary condition of NIST LRE 2015. The...UBM is trained on the balanced training set in 5 iterations (up to 15 hours of ran- domly selected training utterances per language). The dimen

  9. "La casa delle donne. Sulla storia della traduzione italiana di Dom kobiet di Zofia Nałkowska" [La casa delle donne. The history of the Italian translation of Dom kobiet by Zofia Nałkowska

    Directory of Open Access Journals (Sweden)

    Anita Kłos

    2015-12-01

    Full Text Available "In 1930 Sibilla Aleramo translated the play Dom kobiet by Polish writer Zofia Nałkowska into Italian. This three-act drama, probably the first play with only female characters in the history of theatre, was set in Warsaw the same year and was suddenly a huge success in Poland. Aleramo’s translation has remained unpublished and has been preserved (as a manuscript and a typescript draft in the author’s archive belonging to the Fondazione Istituto Gramsci in Rome. The paper focuses on the history of this text, based mainly on the analysis of Nałkowska’s diary and unpublished letters and documents from Aleramo’s archive."

  10. Domestic violence surveillance system: a model Sistema de vigilancia de violencia doméstica: un modelo

    Directory of Open Access Journals (Sweden)

    Rafael Espinosa

    2008-01-01

    Full Text Available OBJECTIVE: To develop a domestic violence surveillance system. MATERIAL AND METHODS: The strategies included implementation of a standard digitalized reporting and analysis system along with advocacy with community decision makers, strengthening inter-institutional attention networks, consultation for constructing internal flow charts, sensitizing and training network teams in charge of providing health care in cases of domestic violence and supporting improved public policy prevention initiatives. RESULTS: A total of 6 893 cases were observed using 2004 and 2005 surveillance system data. The system reports that 80% of the affected were women, followed by 36% children under 14 years. The identified aggressors were mainly females' partners. The system was useful for improving victim services. CONCLUSIONS: Findings indicate that significant gains were made in facilitating the attention and treatment of victims of domestic violence, improving the procedural response process and enhancing the quality of information provided to policy-making bodies.OBJETIVO: Desarrollar un sistema de vigilancia sobre violencia doméstica. MATERIAL Y MÉTODOS: Las estrategias incluyeron la implementación de un sistema de análisis y reporte digitalizado estándar, a la par de hacer conciencia entre los tomadores de decisiones a nivel comunitario, fortalecer redes de atención interinstitucionales, consultoría para el diseño de diagramas de flujo internos, equipos de sensibilización y entrenamiento a cargo de proveer cuidados de salud en casos de violencia doméstica y de dar a poyo a iniciativas de prevención como parte de políticas públicas mejoradas. RESULTADOS: Se observó un total de 6893 casos a partir de datos de 2004 y 2005 de un sistema de vigilancia. El sistema informa que 80% de las víctimas fueron mujeres, seguidas de 36% de niños menores de 14 años. Los agresores identificados fueron principalmente los compañeros de las mujeres. El sistema

  11. From DNS to RANS: A Multi-model workflow to understand the Influence of Hurricanes on Generating Turbidity Currents in the Gulf of Mexico

    Science.gov (United States)

    Syvitski, J. P.; Arango, H.; Harris, C. K.; Meiburg, E. H.; Jenkins, C. J.; Auad, G.; Hutton, E.; Kniskern, T. A.; Radhakrishnan, S.

    2016-12-01

    A loosely coupled numerical workflow is developed to address land-sea pathways for sediment routing from terrestrial and coastal sources, across the continental shelf and ultimately down the continental slope canyon system of the northern Gulf of Mexico (GOM). Model simulations represent a range of environmental conditions that might lead to the generation of turbidity-currents. The workflow comprises: 1) A simulator for the water and sediment discharged from rivers into the GOM with WMBsedv2 with calibration using USGS and USACE gauged river data; 2) Domain grids and bathymetry (ETOPO2) for the ocean models and realistic seabed sediment texture grids (dbSEABED) for the sediment transport models; 3) A spectral wave action simulator (10 km resolution) (WaveWatch III) driven by GFDL - GFS winds; 4) A simulator for ocean dynamics (ROMS) forced with ECMWF ERA winds; 5) A simulator for seafloor resuspension and transport (CSTMS); 6) Simulators (HurriSlip) of seafloor failure and flow ignition locations for boundary input to a turbidity current model; and 7) A RANS turbidity current model (TURBINS) to route sediment flows down GOM canyons, providing estimates of bottom shear stresses. TURBINS was developed first as a DNS model and then converted to an LES model wherein a dynamic turbulence closure scheme was employed. Like most DNS to LES model comparisons (these being done by the UCSB team), turbulence scaling allowed for higher Re applications but were found still not capable of simulating field scale (GOM continental canyons) environments. The LES model was next converted to a non-hydrostatic RANS model capable of field scale applications but only with a daisy-chain approach to multiple model runs along the simulated canyon floor. These model adaptations allowed the workflow to be tested for the year 1-Oct-2007 to 30-Sep-2008 that included two domain Hurricanes (Ike and Gustav). The RANS-TURBINS employed further boundary simplifications on both sediment erosion and

  12. Marmaras espacios inteligentes proyecto orientado a la viabilidad de construir vivienda Domótica en Cundinamarca

    OpenAIRE

    Barrera Sogamoso, Jazmín Alexandra; Malagón Rayo, Reinaldo; Porras Alarcón, Diana Marcela

    2013-01-01

    En la actualidad el avance de la tecnología ofrece día tras día la posibilidad de mejorar las condiciones de vida ya sea en el trabajo o en el hogar, La Domótica hace referencia a la puesta en marcha de diversos sistemas capaces de integrarse entre sí con el fin de generar espacios más seguros, ahorradores y confortables. En países como Estados Unidos, Japón y algunos de la Comunidad Europea, estas tendencias son cada vez más frecuentes, sin embargo en países como Colombia se desconocen algun...

  13. Estado contemporâneo e intervenção no domínio econômico

    Directory of Open Access Journals (Sweden)

    Marlene Kempfer

    2012-12-01

    Full Text Available Sob uma perspectiva semântico-pragmática, este artigo estipula uma definição jurídico-positiva de “intervenção do Estado sobre o domínio econômico” como a atuação do Estado sobre atividades econômicas em sentido estrito, no campo de titularidade da iniciativa privada, como também sobre os serviços públicos não essenciais, chamados impróprios. Essa intervenção do Estado pode ocorrer por participação direta (art.173, CF/88 ou na condição de agente normativo e regulador(art. 174, CF/88, exercendo as funções de fiscalização, incentivo e planejamento.

  14. Asalto rápido, ataque preventivo. El teatro doméstico de la guerra y las nuevas disidencias

    Directory of Open Access Journals (Sweden)

    Mary Louise Pratt

    2003-10-01

    Full Text Available Las tácticas para reprimir la disidencia en el escenario doméstico en EE.UU son las mismas que aprovechan las acciones militares en el exterior: asalto rápido y ataque preventivo. La derecha opera por medio de entrelazadas que sin embargo no logran reinterpelar la ciudadanía de manera consistente o satisfactoria. L a derechización actual en EE.UU tiene antecedentes en el macartismo y la Primera Guerra Mundial, y orígenes en un nuevo activismo desarrollado a partir de 1968 y ayudado por la monopolización de los medios. Sin embargo, el internet ofrece un poderoso apoyo a las prácticas opositoras, y crea un nuevo agente político, el público global.

  15. La unidad doméstica en la ciudad de Buenos Aires a mediados del siglo XVIII.

    Directory of Open Access Journals (Sweden)

    Maximiliano Camarda

    2011-08-01

    Full Text Available A partir de datos censales, el artículo analiza la  dinámica económica, composición y características de las unidades domésticas en el Buenos Aires del siglo XVIII. De manera específica, el trabajo busca identificar los patrones que guiaban a los dueños a alquilar a determinadas personas los cuartos de sus casas, tanto en la que habitaban como también otras. Mediante el acercamiento a esta problemática localizada, el trabajo busca aproximarse a un problema histórico de mayor amplitud, cual es, los patrones de sociabilidad bonaerenses en el período estudiado.

  16. Planos individuais de segurança para vítimas de violência doméstica

    OpenAIRE

    Ferreira, Diogo Romeu Raposo

    2017-01-01

    A presente investigação centra-se nos Planos Individuais de Segurança, introduzidos no ordenamento jurídico nacional no ano de 2015, através da Lei n.º 129/2015, de 3 de setembro (Assembleia da República [AR], 2015b), que fixa o regime jurídico da prevenção da violência doméstica e da proteção e assistência das suas vítimas. Um Plano Individual de Segurança consiste na elaboração de um conjunto de conselhos, recomendações e medidas de proteção pessoal, a definir individualmente com cada ví...

  17. Análisis de biodiesel preparado a partir de residuos de aceite doméstico, mediante RMN.

    OpenAIRE

    Cedron, Torres, Juan Carlos; Universidad de Ingeniería y Tecnología - UTEC; Perú; Cedron, Torres, Juan Carlos

    2014-01-01

    Publicado en Revista Sociedad Química del Perú el 14/02/2014 Se preparó biodiesel a partir de residuos de aceite doméstico, mediante la reacción de transesterificación usando etanol. El rendimiento de la reacción fue del 78%, y el producto obtenido fue caracterizado por sus propiedades fisicoquímicas. Un análisis detallado del espectro de 1H-RMN permitió calcular que la conversión de triglicéridos en ésteres monoalquilados fue del 98,82%, lo cual indica que el biodiesel tiene la calidad re...

  18. Desenvolvimento de um novo método RANS-based para a aeroacústica computacional de jatos de alta velocidade.

    OpenAIRE

    Carlos Roberto Ilário da Silva

    2011-01-01

    Uma nova ferramenta de aeroacústica computacional baseada em simulações RANS (Reynolds Averaged Navier-Stokes) foi desenvolvida para a predição do ruído gerado pelo escoamento tri-dimensional de jatos complexos. O método é denominado de LRT o qual surgiu da combinação da analogia acústica de Lighthill com o método de acústica geométrica Ray-Tracing. A grande vantagem da utilização do método LRT para predições de ruído é que este determina não apenas as fontes sonoras presentes...

  19. Distintas o iguales: las diferencias en el trabajo doméstico de las parejas de doble ingreso entre las uniones libres y los matrimonios

    Directory of Open Access Journals (Sweden)

    Landy Sánchez Peña

    2016-01-01

    Full Text Available La brecha de género en el trabajo doméstico ha sido ampliamente estudiada en México, mostrando gradientes por nivel socioeconómico y diferencias asociadas a la participación de las mujeres en el trabajo extradoméstico. En este artículo indagamos en qué medida ambos procesos dan forma al reparto del trabajo doméstico entre parejas de doble provee - dor que difieren por tipo de unión. Basamos el análisis empírico en la ENIGH 2010 utilizando modelos de regresión. Nuestros resultados sugieren que la brecha de género en el trabajo doméstico es menor en las parejas en unión libre en comparación con las pa - rejas casadas, aun tomando en cuenta efectos de selección. Entre las primeras, la brecha se reduce mayormente conforme aumenta el ingreso, de modo que las parejas en unión libre y de alto ingreso representan el arreglo más equitativo en la división sexual del trabajo no remunerado. Ello se debe a que las mujeres en unión libre dedican menos tiempo al trabajo doméstico que las casadas, mientras que entre los varones no observamos diferencias.

  20. BounceBack™ capsules for reduction of DOMS after eccentric exercise: a randomized, double-blind, placebo-controlled, crossover pilot study

    Directory of Open Access Journals (Sweden)

    Singh Betsy B

    2009-06-01

    Full Text Available Abstract Background Delayed onset muscle soreness (DOMS is muscle pain and discomfort experienced approximately one to three days after exercise. DOMS is thought to be a result of microscopic muscle fiber tears that occur more commonly after eccentric exercise rather than concentric exercise. This study sought to test the efficacy of a proprietary dietary supplement, BounceBack™, to alleviate the severity of DOMS after standardized eccentric exercise. Methods The study was a randomized, double-blind, placebo-controlled, crossover study. Ten healthy community-dwelling untrained subjects, ranging in age from 18–45 years, were enrolled. Mean differences within and between groups were assessed inferentially at each data collection time-point using t-tests for all outcome measures. Results In this controlled pilot study, intake of BounceBack™ capsules for 30 days resulted in a significant reduction in standardized measures of pain and tenderness post-eccentric exercise compared to the placebo group. There were trends towards reductions in plasma indicators of inflammation (high sensitivity C-reactive protein and muscle damage (creatine phosphokinase and myoglobin. Conclusion BounceBack™ capsules were able to significantly reduce standardized measures of pain and tenderness at several post-eccentric exercise time points in comparison to placebo. The differences in the serological markers of DOMS, while not statistically significant, appear to support the clinical findings. The product appears to have a good safety profile and further study with a larger sample size is warranted based on the current results.

  1. A prospective study on obesity and subcutaneous fat patterning in relation to breast cancer in post-menopausal women participating in the DOM project

    NARCIS (Netherlands)

    den Tonkelaar, I.; Seidell, J C; Collette, H J; de Waard van de Spek, FB

    The associations of body fat and body fat distribution with breast cancer risk were examined in a prospective study in 9,746 post-menopausal women with a natural menopause, aged 49-66 at intake, participating in a breast cancer screening project (the DOM project in Utrecht). During a follow-up

  2. Violência doméstica, álcool e outros fatores associados: uma análise bibliométrica

    Directory of Open Access Journals (Sweden)

    Aline Gomes Martins

    2017-01-01

    Full Text Available El presente estudio tiene como objetivo realizar una investigación bibliométrica acerca de la relación entre violencia doméstica y alcohol a partir de revistas disponi - bles en la página de la CAPES entre 2003 y 2013. Los resultados muestran que las principales víctimas son mujeres y niños y el principal agresor el hombre, seguido de la mujer. El tipo de violencia más frecuente entre los sujetos que se analizaron es la física, con predominio de la sexual en situaciones de violencia en contra de niños y adolescentes. En lo que se refiere al consumo de alcohol, el hombre es el princi - pal usuario. Otros factores más allá del alcohol son apuntados como asociados a la violencia doméstica como escolaridad, pobreza, historia familiar de violencia, entre otros. Algunos puntos no fueron suficientemente contemplados por los artículos con - siderados, como la violencia conyugal homosexual, violencia doméstica en el campo, violencia doméstica en contra de ancianos y discapacitados. Esos temas aparecen como lagunas con las que los investigadores deben tener especial atención.

  3. Importância e domínios de avaliação psicológica: um estudo com alunos de Psicologia

    Directory of Open Access Journals (Sweden)

    Ana Paula Porto Noronha

    2007-08-01

    Full Text Available Essa pesquisa investigou a importância conferida e a percepção de domínio de estudantes de Psicologia quanto a competências de avaliação psicológica. Participaram do estudo 112 estudantes, predominantemente do sexo feminino e da região Centro-Oeste, de todos os períodos do curso. Foi utilizado um questionário baseado nas definições das competências essenciais apontadas pela American Psychological Association, em que constaram 20 itens que foram respondidos separadamente para o domínio e importância, abordando temas como o conhecimento de construtos psicológicos, saber usar e interpretar testes, entre outros. Os itens considerados menos importantes foram ter noções de estatística e ter conhecimento de ampla gama de testes. Algumas contradições foram observadas ao comparar a importância e o domínio, a exemplo das noções de estatística. A análise de diferenças de média revelou poucas diferenças ao observar os itens de importância entre os diferentes anos do curso, porém os de domínio, em sua maioria, apresentaram diferenças significativas.

  4. Kritiskās domāšanas stratēģijas latviešu valodas pamatprasmju attīstīšanai.

    OpenAIRE

    Stepanova, Ināra

    2006-01-01

    Pētījuma „Kritiskās domāšanas stratēģijas latviešu valodas pamatprasmju attīstīšanai 1.- 4. klasē” mērķis ir pētīt un analizēt kritiskās domāšanas stratēģiju ietekmi uz 1.- 4. klašu skolēnu latviešu valodas pamatprasmju attīstīšanu. Diplomdarbā autore analizē teorētisko literatūru par kritisko domāšanu pedagoģiskajā procesā, pēta un analizē jaunākā skolas vecuma bērnu valodas pamatprasmju attīstīšanas pedagoģiski psiholoģiskos līdzekļus, veic pedagoģisko eksperimentu par kritiskās domāšanas s...

  5. Microbial use of low molecular weight DOM in filtered and unfiltered freshwater: Role of ultra-small microorganisms and implications for water quality monitoring.

    Science.gov (United States)

    Brailsford, F L; Glanville, H C; Marshall, M R; Golyshin, P N; Johnes, P J; Yates, C A; Owen, A T; Jones, D L

    2017-11-15

    Dissolved organic matter (DOM) plays a central role in regulating productivity and nutrient cycling in freshwaters. It is therefore vital that we can representatively sample and preserve DOM in freshwaters for subsequent analysis. Here we investigated the effect of filtration, temperature (5 and 25°C) and acidification (HCl) on the persistence of low molecular weight (MW) dissolved organic carbon (DOC), nitrogen (DON) and orthophosphate in oligotrophic and eutrophic freshwater environments. Our results showed the rapid loss of isotopically-labelled glucose and amino acids from both filtered (0.22 and 0.45μm) and unfiltered waters. We ascribe this substrate depletion in filtered samples to the activity of ultra-small (<0.45μm) microorganisms (bacteria and archaea) present in the water. As expected, the rate of C, N and P loss was much greater at higher temperatures and was repressed by the addition of HCl. Based on our results and an evaluation of the protocols used in recently published studies, we conclude that current techniques used to sample water for low MW DOM characterisation are frequently inadequate and lack proper validation. In contrast to the high degree of analytical precision and rigorous statistical analysis of most studies, we argue that insufficient consideration is still given to the presence of ultra-small microorganisms and potential changes that can occur in the low MW fraction of DOM prior to analysis. Copyright © 2017 Elsevier B.V. All rights reserved.

  6. Desenvolvendo tecnologia para prevenção e tratamento de emergências domésticas para cegos

    Directory of Open Access Journals (Sweden)

    Lorita Marlena Freitag Pagliuca

    1996-03-01

    Full Text Available O aprimoramento do desenvolvimento dos órgãos dos sentidos se dá pela percepção de estímulos do meio, o que leva o homem à apreensão do conhecimento. A pessoa privada da visão conta com seus sentidos remanescentes para sua relação com o que a rodeia. O cego está sujeito a emergências domésticas, comuns a todas as pessoas, mas tem dificuldades de acesso a processos educativos que abordem a prevenção e tratamento destas emergências. Em um Curso de Prevenção e Tratamento de Emergências Domésticas para Cegos, desenvolveu-se tecnologia pedagógica abordando anatomia e fisiologia dos sistemas esquelético, circulatório e pulmonar, além da prevenção e tratamento para desobstrução das vias aéreas, parada cardio-pulmonar, queimaduras, choque elétrico, traumas, hemorragias, envenenamentos, desmaios, convulsões e uso de medicação oral. Utilizou-se esqueleto humano, manequim, moldes, papéis, tubos de plástico e borracha e, principalmente, comunicação verbal e táctil. Os conteúdos transmitidos foram aplicados em situações simuladas. A tecnologia mostrou-se eficaz pela capacidade demonstrada pelos cegos através da verbalização e repetição dos procedimentos.

  7. PERCEPÇÃO AMBIENTAL DOS VISITANTES DO PARQUE MUNICIPAL DOM NIVALDO MONTE EM NATAL/RN

    Directory of Open Access Journals (Sweden)

    Maria Agripina Rebouças

    2015-07-01

    Full Text Available O presente artigo apresenta a percepção ambiental dos visitantes do Parque Dom Nivaldo Monte, também conhecido Parque da Cidade, em Natal/RN. A metodologia foi determinada por entrevistas semiestruturadas com auxílio de formulários aplicados a 50 visitantes do parque, em dias e horários diversificados no período de outubro a dezembro de 2012. Constatou-se que os visitantes do Parque Dom Nivaldo Monte utilizam o espaço para desenvolver atividades físicas ou para simples admiração paisagística, além de considerá-lo um espaço de lazer para a família e um ambiente que transmite paz e qualidade de vida. Independentemente do nível de escolaridade os visitantes do parque, apresentaram considerável grau de valorização do espaço, por demonstrarem interesse em conservar os recursos naturais para garantir a sustentabilidade do local. Constatou-se também que é de interesse dos visitantes a participação em projetos de Educação Ambiental nas dependências do parque, a fim de serem envolvidos em ações de conservação das espécies endêmicas de fauna e flora, além de salvaguardar as nascentes de corpos d’água nos limites do parque, e anda, falta de comprometimento das autoridades para assegurar a integridade física do parque.

  8. Chemical characteristics of dissolved organic matter (DOM) in relation to heavy metal concentrations in soil water from boreal peatlands after clear-cut harvesting

    Science.gov (United States)

    Kiikkilä, O.; Nieminen, T.; Starr, M.; Ukonmaanaho, L.

    2012-04-01

    Boreal peatlands form an important terrestrial carbon reserve and are a major source of dissolved organic matter (DOM) to surface waters, particularly when disturbed through forestry practices such as draining or timber harvesting. Heavy metals show a strong affinity to organic matter and so, along with DOM, heavy metals can be mobilized and transported from the soil to surface waters and sediments where they may become toxic to aquatic organisms and pass up the food chain. The complexation of heavy metals with DOM can be expected to be related and determined by the chemical characteristics of DOM and oxidation/reducing conditions in the peat. We extracted interstitial water from peat samples and determined the concentrations of dissolved organic carbon (DOC), dissolved organic nitrogen (DON) and Al, Cu, Zn and Fe in various fractions of DOM isolated by adsorption properties (XAD-8 fractionation) and molecular-weight (ultrafiltration). The peat samples were taken from 0-30 and 30-50 cm depth in drained peatland catchments two years after whole-tree or stem-only clear-cut harvesting (Scots pine or Norway spruce) had been carried out. The samples from the upper layer had been subject to alternating saturation/aeration conditions while the deeper layer had been continuously under the water table. The fractionation of DOC and DON according to both adsorption properties and molecular-weight fractions clearly differed between the upper and lower peat layers. While the hydrophobic acid fraction contained proportionally more DOC and DON than the hydrophilic acid fraction in the upper peat layer the results were vice versa in the lower peat layer. High-molecular-weight compounds (> 100 kDa) were proportionally more abundant in the upper and low-molecular-weight compounds (free metal ions in solution. There were no clear differences in the chemical characteristics of DOC or DON or heavy metal concentrations between the two harvesting treatments.

  9. Sistema de grupos sanguíneos AB em felídeos neotropicais e compatibilidade com gatos domésticos

    Directory of Open Access Journals (Sweden)

    T.D.P. Silva

    Full Text Available RESUMO O principal sistema de grupos sanguíneos reconhecido para gatos é o AB. Os felinos apresentam anticorpos naturais contra o antígeno do tipo sanguíneo a que não pertencem, o que torna os testes de compatibilidade e as tipagens sanguíneas importantes na prevenção de reações transfusionais. O objetivo deste estudo foi realizar a tipagem sanguínea de oito gatos-mouriscos (Puma yagouaroundi, oito jaguatiricas (Leopardus pardalis, sete gatos-palheiros (Leopardus colocolo, sete gatos domésticos (Felis catus da raça Persa e oito gatos domésticos sem raça definida (SRD, bem como realizar testes de compatibilidade entre os tipos sanguíneos iguais das diferentes espécies, para avaliar a possibilidade de transfusões interespecíficas. A técnica empregada para a tipagem foi a hemaglutinação em tubos de ensaio. A ocorrência do tipo sanguíneo tipo A foi de 100% entre as jaguatiricas, os gatos-palheiros e os gatos Persas e de 85,72% entre os gatos SRD. A ocorrência do tipo B foi de 100% nos gatos-mouriscos e de 14,28% nos gatos SRD. Considerando os testes de compatibilidade sanguínea, 87,5% (n=4 das jaguatiricas foram incompatíveis com os gatos domésticos, 100% (n= 6 dos gatos-palheiros foram compatíveis com os gatos domésticos e 100% (n= 4 dos gatos-mouriscos foram incompatíveis com os gatos domésticos do tipo B.

  10. The response of water quality variation in Poyang Lake (Jiangxi, People's Republic of China) to hydrological changes using historical data and DOM fluorescence.

    Science.gov (United States)

    Yao, Xin; Wang, Shengrui; Ni, Zhaokui; Jiao, Lixin

    2015-02-01

    Poyang Lake is a unique wetland system that has evolved in response to natural seasonal fluctuations in water levels. To better characterize the response of water quality to hydrological variation, historical data were analyzed in combination with dissolved organic matter (DOM) fluorescence samplings conducted in situ. Historical data showed that long-term changes in water quality are mainly controlled by the sewage inputs to Poyang Lake. Monthly changes in water quality recorded during 2008 and 2012 suggest that water level may be the most important factor for water quality during a hydrological year. DOM fluorescence samples were identified as three humic-like components (C1, C2, and C3) and a protein-like component (C4). These obvious compositional changes in DOM fluorescence were considered to be related to the hydrodynamic differences controlled by water regimen. Principal component analysis (PCA) showed higher C1 and C2 signals during a normal season than the wet season, whereas C3 was lower, and C4 was higher in the dry season than in the wet or normal seasons. From the open lake to the Yangtze River mouth, increased C3 component carried by backflows of the Yangtze River to the lake resulted in these unique variations of PCA factor 2 scores during September. These obvious compositional changes in DOM fluorescence were considered to be related to the hydrodynamic differences controlled by water regimen. DOM fluorescence could be a proxy for capturing rapid changes in water quality and thereby provide an early warning signal for the quality of water supply.

  11. Biogeochemical and Remote Sensing Approaches to Evaluating the Sources and Fates of DOM and Particles in the U.S. Middle Atlantic Bight

    Science.gov (United States)

    Mannino, A.; Russ, M. E.; Hooker, S. B.

    2007-12-01

    Estuaries and the coastal ocean experience a high degree of variability in the composition and concentration of particulate and dissolved organic matter (DOM) as a consequence of riverine/estuarine fluxes of terrigenous DOM, sediments, detritus and nutrients into coastal waters and associated phytoplankton blooms. Our approach integrates biogeochemical measurements (elemental content, stable isotopes and molecular analyses), optical properties (absorbance) and remote sensing to examine the sources and fates of organic matter in the U.S. Middle Atlantic Bight (MAB). Remote sensing of chromophoric DOM (CDOM) is applied to track terrigenous DOM and quantify dissolved organic carbon (DOC) within the coastal ocean. Satellite validation analyses demonstrate successful retrieval of particulate organic carbon (POC), DOC, and CDOM absorption coefficient (aCDOM) for coastal ocean waters using the MODIS-Aqua and SeaWiFS satellite sensors with absolute percent differences between satellite and field measurements of 8±6.4% for DOC, 18±15% for aCDOM(355 nm) and 25±17% for POC. The seasonal processes that influence CDOM distributions in the MAB include freshwater discharge, photooxidation, and wind-induced vertical mixing in autumn and winter. DOC and POC distributions are driven primarily by river/estuary discharge, net ecosystem production, and the ocean circulation pattern along the shelf and continental slope. Satellite data analysis of aCDOM can be used to quantify photooxidation rates, track the inputs of terrigenous DOM from rivers or estuaries into the coastal ocean and beyond, and trace water masses with different CDOM signatures. Satellite-derived DOC and POC can be applied to quantify the fluxes of DOC and POC entering the coastal ocean and exported from the continental margin to the open ocean, estimate net C production, and assess the standing stocks of DOC and POC.

  12. [Using ultraviolet-visible ( UV-Vis) absorption spectrum to estimate the dissolved organic matter (DOM) concentration in water, soils and sediments of typical water-level fluctuation zones of the Three Gorges Reservoir areas].

    Science.gov (United States)

    Li, Lu-lu; Jiang, Tao; Lu, Song; Yan, Jin-long; Gao, Jie; Wei, Shi-qiang; Wang, Ding-yong; Guo, Nian; Zhao, Zhena

    2014-09-01

    Dissolved organic matter (DOM) is a very important component in terrestrial ecosystem. Chromophoric dissolved organic matter (CDOM) is a significant constituent of DOM, which can be measured by ultraviolet-visible (UV-Vis) absorption spectrum. Thus the relationship between CDOM and DOM was investigated and established by several types of models including single-wavelength model, double-wavelength model, absorption spectrum slope (S value) model and three-wavelength model, based on the UV-Vis absorption coefficients of soil and sediment samples (sampled in July of 2012) and water samples (sampled in November of 2012) respectively. The results suggested that the three-wavelength model was the best for fitting, and the determination coefficients of water, soil and sediment data were 0. 788, 0. 933 and 0. 856, respectively. Meanwhile, the nominal best model was validated with the UV-Vis data of 32 soil samples and 36 water samples randomly collected in 2013, showing the RRMSE and MRE were 16. 5% and 16. 9% respectively for soil DOM samples, 10. 32% and 9. 06% respectively for water DOM samples, which further suggested the prediction accuracy was higher in water DOM samples as compared with that in soil DOM samples.

  13. Controlo inteligente de percurso para encaminhamento inter-domínio

    OpenAIRE

    Fonte, Alexandre José Pereira Duro da

    2011-01-01

    Tese de doutoramento em em Engenharia Informática, apresentada à Faculdade de Ciências e Tecnologia da Universidade de Coimbra The Internet is being increasingly criticized for the poor Quality of Service (QoS) guarantees it provides across the boundaries of Autonomous Systems (AS). The Border Gateway Protocol (BGP) protocol lies at the root of this problem, because its route discovery and path selection mechanisms are agnostic with regard to any performance or QoS metrics. Underlyin...

  14. Ticks on domestic animals in Pernambuco, Northeastern Brazil Carrapatos em animais domésticos em Pernambuco, Nordeste do Brasil

    Directory of Open Access Journals (Sweden)

    Filipe Dantas-Torres

    2009-09-01

    Full Text Available The objective of this article was to discuss some aspects of ticks associated with domestic animals in the State of Pernambuco, northeastern Brazil, based on a literature review and present new data obtained from recent tick collections carried out in this northeastern Brazilian state. From August 2007 to June 2008, 1,405 ticks were collected and five species were identified: Amblyomma cajennense (Fabricius, 1787, Amblyomma ovale Koch, 1844, Dermacentornitens Neumann, 1897, Rhipicephalus (Boophilus microplus (Canestrini, 1887, and Rhipicephalus sanguineus (Latreille,1806. Dogs from urban areas were found exclusively infested by R. sanguineus, whereas dogs from rural areas were found infested by A. cajennense, A. ovale, R. (B. microplus, and R. sanguineus. The only tick species found on cattle and goats was R. (B. microplus. Horses were found infested by D. nitens and at a lesser extent by A. cajennense and R. (B. microplus. The only tick species found on donkeys was D. nitens. This study confirms the presence of A. cajennense inPernambuco and describes for the first time the presence of A. ovale in this state. The medical and veterinary relevance and control of ticks associated with domestic animals in Pernambuco are also briefly discussed.O objetivo desse artigo é discutir alguns aspectos relacionados aos carrapatos que parasitam animais domésticos no Estado de Pernambuco com base numa revisão da literatura e apresentar novos dados obtidos a partir de recentes coletas de carrapatos realizadas nesse estado do nordeste brasileiro. De agosto de 2007 a junho de 2008, 1.405 carrapatos foram coletados e cinco espécies foram identificadas: Amblyomma cajennense (Fabricius, 1787, Amblyomma ovale Koch, 1844, Dermacentor nitens Neumann, 1897, Rhipicephalus (Boophilus microplus (Canestrini, 1887 e Rhipicephalus sanguineus (Latreille, 1806. Cães de áreas urbanas foram encontrados infestados exclusivamente por R. sanguineus ao passo que cães de

  15. Violência doméstica infantil: abordagem da enfermagem = Domestic violence child: approach to nursing

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    Fernanda Lise

    2012-01-01

    Full Text Available Este estudo visa aprofundar a discussão sobre a violência doméstica contra crianças e adolescentes. Trata-se de uma revisão sistemática da literatura na perspectiva de caracterizar a produção do conhecimento e identificar os fatores de vulnerabilidade para maus-tratos infantis, bem como conhecer quais são as estratégias utilizadas pelo enfermeiro (a na consulta de Enfermagem à família em situação de violência infantil. Através da bibliografia consultada, verificou-se que crianças e adolescentes do sexo feminino são submetidas a situações de violência com maior freqüência quando comparadas as do sexo masculino; elas ainda apresentam maior risco para o infanticídio, abuso sexual, violência física e nutricional, negligência bem como, para a prostituição forçada. A literatura nacional não permitiu identificar as estratégias utilizadas pelo enfermeiro (a na consulta ao familiar da criança e adolescente vítima de violência doméstica pela ausência de publicações a respeito desta temática, conforme a metodologia utilizada neste estudo.This study aims to deepen the discussion about domestic violence against children and adolescents. This is a systematic review of literature from the perspective of characterizing the production of knowledge and identify the factors of vulnerability to abuse from children and know what are the strategies employed by nurses in Nursing consultation to family under situation of child abuse. Through the literature, we found that children and adolescent girls are submitted to situations of violence more frequently when compared to males; they still have a higher risk for infanticide, sexual abuse, physical and nutritional violence, and negligence as well as for forced prostitution. The national literature failed to identify the strategies used by nurses when consulting the family of the child and adolescent victims of domestic violence by the absence of publications on this subject

  16. Memória urbana da avenida Dom Severino: análise das edificações

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    Juliana Lopes Aragão

    2015-12-01

    Full Text Available Essa é uma pesquisa PIBIC/CNPq realizada pelo Departamento de Construção Civil e Arquitetura da Universidade Federal do Piauí (UFPI. Tal trabalho teve início no ano de 2010, após a observação das transformações ocorridas em uma importante via da zona leste da cidade. No momento, esse trabalho tem a participação de três bolsistas, que dividem suas ações em campos distintos para o levantamento de dados. O objetivo desse trabalho é analisar o impacto provocado pela construção da ponte estaiada no cenário urbano da Avenida Dom Severino. A Avenida teve seu uso e suas dimensões alteradas sem um planejamento prévio, provocando assim um problema urbano. A primeira etapa consistiu na delimitação da área a ser analisada, que foi o trecho da Avenida Dom Severino, localizado entre as Avenidas Nossa Senhora de Fátima e Homero Castelo Branco. Estabelecida essa área, partimos para a confecção de um perfil layout das fachadas. A segunda etapa tratou do levantamento nos órgãos da prefeitura e da SDU-Leste (Superintendência de Desenvolvimento Urbano, responsável pelas informações dos imóveis dessa via, dados sobre os tipos de uso das edificações. E a etapa final foi a confecção de um banco de dados para a inserção das informações sobre os imóveis, quanto à existência ou não de reformas, e a dimensão dessas reformas. Buscou-se informações sobre a posse dos imóveis, e as posteriores negociações que transformaram uso residencial em comercial. Paralelamente pesquisou-se as informações sobre a ponte estaiada e o processo de desocupação dos terrenos que eram de propriedade privada e que após a construção da ponte teve que ser negociada para se incorporar à mesma.

  17. Prevalencia de helmintos intestinales en gatos domésticos del departamento del Quindío, Colombia

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    Diana Marcela Echeverry

    2012-05-01

    Full Text Available Introducción. Las enfermedades producidas por helmintos están ampliamente distribuidas en elmundo y muchas de ellas se consideran zoonosis. Los animales de compañía cumplen un papeltrascendental en la transmisión a los humanos. Objetivo. Determinar la prevalencia de helmintos intestinales en gatos del departamento del Quindío. Materiales y métodos. Se estudiaron 121 gatos domésticos del departamento del Quindío, delos cuales se registraron los datos de sexo, edad y condición corporal. Se recolectaron heces y seprocesaron mediante las técnicas de Ritchie modificada y de Kato-Katz. Resultados. De los 121 gatos, 42,14 % (IC95%: 33,35-50,94 y 45,45 % (IC95%: 36,58-54,32 resultaronparasitados con alguna especie de helminto adulto según la presencia de huevos en sus heces,mediante las técnicas de Ritchie y de Kato-Katz, respectivamente. Toxocara cati fue el parásito másprevalente (Ritchie: 37,2 %; Kato-Katz: 43 %, seguido por Ancylostoma spp. (Ritchie: 7,43 %; Kato-Katz: 5,78 % y Aelurostrongylus abstrusus (Ritchie: 0,82 %.Sesenta y cinco (53,71 % gatos eran hembras y 56 (46,28 % eran machos; la prevalencia de infecciónfue similar en ambos sexos. Los felinos mayores de 4 años de edad presentaron mayor prevalenciade parásitos (81,8 %, seguidos por los de 1 a 4 años (48,8 % y, por último, por los menores de unaño (28,6 %. Se encontró una buena condición corporal en 77,68 % y este grupo presentó menorfrecuencia de helmintos intestinales. Conclusión. La prevalencia de helmintos intestinales en gatos domésticos del departamento delQuindío fue de 43,8 %, lo que hace necesario establecer programas de vigilancia y prevención en lapoblación humana y felina.   doi: http://dx.doi.org/10.7705/biomedica.v32i3.439

  18. Revisão crítica sobre o atendimento a homens autores de violência doméstica e familiar contra as mulheres

    OpenAIRE

    Lima,Daniel Costa; Büchele,Fátima

    2011-01-01

    Este artigo representa uma revisão crítica sobre intervenções com homens autores de violência (HAV) doméstica e familiar contra a mulher, tendo como base a revisão de literatura nacional e estrangeira sobre o tema. Somado a esta revisão, o artigo traz resultados de um estudo de caso com abordagem qualitativa sobre um programa governamental de prevenção e atenção à violência doméstica e familiar do Sul do Brasil. Além do trabalho desenvolvido com mulheres em situação de violência, esse program...

  19. Status efter nye klagenævnsafgørelser og dom om gyldigheden af tilladelser til vindmølleparker og SMV-direktivets retsvirkning

    DEFF Research Database (Denmark)

    Pagh-Rasmussen, Peter

    2017-01-01

    Som en del læsere af Tidsskrift for Miljø nok er bekendt med, betød EU-domstolen dom i oktober 2016 i sag C-290/15, at der blev rejst tvivl om gyldigheden af den danske vindmøllebekendtgørelse, fordi bekendtgørelsen var vedtaget uden forudgående miljøvurdering og offentlig høring efter reglerne i...... begrunde opsættende virkning af klager over tilladelser til vindmølleparker. Endvidere har byretten i dom af 9. oktober 2017 i retssag anlagt af naboer mod Natur- og Miljøklagenævnet om en af nævnet stadfæstet tilladelse til vindmøllepark ved Varde afvist, at klagenævnet er rette sagsøgte for sådanne...

  20. Introducción al estudio de los baños domésticos de tradición fenicio-púnica

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    Iván Fumadó Ortega

    2007-01-01

    Full Text Available Quisiera llamar la atención sobre el desatendido estudio de la higiene en la Antigüedad y su estrecha conexión con el urbanismo. Nuevos datos de excavación en yacimientos fenicio-pánicos permiten presentar un mímero de ejemplos de baños domésticos que evidle neian un patrón espacial claramente di/erenciable del que se da en otros ámbitos culturales. Pura subrayar la distribución del cuarto de baño en el interior de la casa empleo el sistema de representación espacial habitual en los estudios de space syntax. Finalizo con una reinterpretación de las estructuras domésticas presentes en el patio ele la casa mauritana hallada en la Ladera Sur de Lixus (Larache, Marruecos.

  1. Memória e filmes domésticos em Super 8: a família Assis em Juiz de Fora - MG

    OpenAIRE

    Musse, Christina Ferraz; Santos, Ana Clara Campos dos

    2017-01-01

    Neste trabalho abordamos a memória como objeto de estudo, a película cinematográfica Super 8 e os filmes domésticos. No embasamento teórico, utilizamos autores como Andreas Huyssen e Pierre Nora (memória), Roger Odin e Lila Foster (filmes domésticos). Nosso objetivo é apresentar os filmes em Super 8 feitos pelo fotógrafo Márcio Assis na década de 1970, a fim de verificar as relações entre sua narrativa oral atual por meio da gravação em áudio de seus comentários do filme, em comparação a sua ...

  2. Violência doméstica e institucional em serviços de saúde: experiências de mulheres

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    Normélia Maria Freire Diniz

    2004-06-01

    Full Text Available Desenvolvido nas capitais Recife, Salvador e Aracaju, em três maternidades públicas, este estudo quantitativo objetivou identificar as manifestações da violência doméstica e institucional na mulher assistida em sub-programas do Programa de Assistência Integral à Saúde da Mulher. Para coleta dos dados, foi utilizado um formulário semi-estruturado. A amostra caracterizou-se por mulheres jovens, domésticas, dependentes economicamente dos companheiros. A maioria das mulheres vivencia a violência conjugal, sendo a dependência financeira o motivo mais mencionado para suportá-la. A falta de vagas caracterizou a violência institucional por omissão. A pesquisa demonstrou que a vivência destas violências traz problemas de saúde para as mulheres, ou os agrava.

  3. Epidemiologia das intoxicações por plantas em herbívoros domésticos na região metropolitana de Curitiba-PR

    OpenAIRE

    Skalski, Juliana

    2015-01-01

    Orientador : Prof. Dr. João Ricardo Dittrich Título da capa : Epidemiologia das intoxicações por plantas de herbívoros domésticos na região metropolitana de Curitiba-PR Título da falsa folha de rosto : Epidemiologia das intoxicações por plantas em herbívoros domésticos na região metropolitana de Curitiba-PR Dissertação (mestrado) - Universidade Federal do Paraná, Setor de Ciências Agrárias, Programa de Pós-Graduação em Ciências Veterinárias. Defesa: Curitiba, 27/03/2015 Inclui ref...

  4. L’humor de Cristòfor de Domènec. Sobre la publicació de Brand, Carnet d’un heterodox (1926)

    OpenAIRE

    Casanovas, Pompeu

    2014-01-01

    L’humor de Cristòfor de Domènec és àcid i pertany a la literatura pamfletària i de combat. Brand, Carnet d’un heterodox és el llibre on el filòsof va recollir els articles publicats sota aquest títol a Justícia Social (1923-1926). Joan Sallarès el va editar a Sabadell, a la impremta Sallent, el 1926. Aquest article analitza l’estil i el contingut del pensament polític de Domènec, la dura crítica a la religió i les seves relacions amb la Colla de Sabadell, les avantguardes i el simbolism...

  5. Tramas e dramas de gênero e de cor: a violência doméstica e familiar contra mulheres negras

    OpenAIRE

    Bruna Cristina Jaquetto Pereira

    2013-01-01

    A presente dissertação tem por tema a violência doméstica e familiar contra mulheres negras. Promovo uma interlocução entre formulações teóricas e pesquisas empíricas consagradas sobre a violência doméstica e familiar contra as mulheres, inscritas no campo das ciências sociais, e o material recolhido em trabalho de campo, bem como busco reconstruir e perscrutar os cenários construídos pelas narrativas das informantes, com vistas a identificar práticas, dinâmicas, representações, sentidos e si...

  6. Subalternidade de gênero: refletindo sobre a vulnerabilidade para violência doméstica contra a mulher

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    Laura Christina Macedo Piosiadlo

    2014-12-01

    Full Text Available Objetivo: Este artigo tem o objetivo de refletir sobre a violência de gênero praticada contra a mulher no espaço intrafamiliar, sobretudo, a relação entre a subalternidade de gênero no âmbito familiar e a vulnerabilidade para este tipo de violência. Resultados: A subalternidade de gênero e a violência contra mulher apresentam-se entrelaçadas na história e, conformam-se por meio da construção de gênero nas sociedades. As mulheres formam um grupo que é violentado, constantemente, e de diversas maneiras, como, agressões e abusos físicos, verbais e sexuais cometidos por parceiros ou ex-parceiros, familiares, amigos, desconhecidos, por instituições públicas ou pelo Estado. Conclusão: Para que os serviços de saúde possam se antecipar às doenças e agravos decorrentes da violência doméstica é essencial compreender os aspectos relacionados à vulnerabilidade da mulher para a violência, como um indicador da iniquidade e da desigualdade social que supera o conceito probabilístico de risco.

  7. Trabajo remunerado, trabajo doméstico y salud: las diferencias cualitativas y cuantitativas entre mujeres y varones

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    Adriana Cecilia Cruz

    2003-08-01

    Full Text Available En este artículo se plantea la relación entre trabajo remunerado, trabajo doméstico y salud, desde la perspectiva de género. La relación entre ambos tipos de trabajo determina las características y el significado de la vida cotidiana. La metodología utilizada conjuntó técnicas cuantitativas y cualitativas. Se aplicó un cuestionario individual a 256 trabajadores y 121 trabajadoras (n = 377 de una moderna industria farmacéutica en México. También se hicieron siete entrevistas en profundidad entre trabajadores seleccionados por conveniencia. Los hallazgos principales muestran que a pesar de las enormes similitudes encontradas en el trabajo asalariado entre mujeres y varones, las diferencias pueden resumirse en dos conjuntos: por un lado, las distintas formas de segregación de género en el mercado de trabajo y, por el otro, en las formas de enfrentar la vida cotidiana. Se puede decir que los determinantes sociales que han cobijado esta desigual situación son resultado de la complejidad de las relaciones de género y dan lugar a diferentes perfiles patológicos y concepciones sobre la salud.

  8. La sala doméstica en santa fe de Bogotá, siglo XIX. El decorado: La sala barroca.

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    Patricica Lara Betancourt.

    2000-12-01

    Full Text Available Las transformaciones en la sala doméstica del grupo social de elite de Santa Fe de Bogotá fueron constantes a lo largo del siglo XIX. Su primera gran transformación correspondió a la sala barroca que remplazó al estrado. Surgida alrededor de 1780, tomó su modelo de las tendencias revolucionarias provenientes de Francia e Inglaterra. Los cambios en la decoración, muebles y objetos del ámbito social fueron el resultado del nacimiento de una nueva sociabilidad que propiciaba el acercamiento y la discusión de ideas y conocimientos ilustrados. El estrado, que había perdurado por casi tres siglos, desapareció con su tarima, alfombra, cojines y muebles ratones. Con ellos también se eliminó la separación tradicional del salón en sectores femenino y masculino. El artículo presenta la reconstrucción de la sala barroca santafereña con base en documentos notariales. Entre sus principales características se encuentran el mayor número de muebles de sentarse, la difusión del canapé, la importancia de los objetos religiosos y los espejos, el adorno de cortinas y colgaduras -rezago del estrado, la alfombra central y las mesas de variadas funciones. El diseño de los muebles responde al estilo barroco.

  9. Aspectos morfológicos do ciclo testicular anual de codorna doméstica (Coturnix coturnix da variedade italiana

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    Antonio Marcos Orsi

    2005-06-01

    Full Text Available A estrutura histológica do epitélio tubular seminífero e os valores do índice gonadossomático de codorna doméstica da variedade italiana, analisados em todas as estações do ano, permitiram caracterizar que a espermatocitogênese nesta ave tem ritmo constante durante a primavera, a fase mais ativa do ciclo testicular anual, o qual, aparentemente, não cessa durante o inverno e o verão. Por outro lado, uma fase quiescente do ciclo observou-se nos períodos inicial e médio do outono, quando a espermiogênese não se completava, levando à não formação de espermatozóides. Os eventos morfológicos testiculares observados parecem se repetir anualmente, durante as estações, sendo bem típica a quiescência outonal, o que permitiu caracterizar na codorna um padrão testicular cíclico circanual, em termos do ritmo da cinética da espermatogênese.

  10. Aplicaciones y experiencias en instalaciones domóticas de viviendas y pequeños establecimientos hoteleros

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    Toledano, José Carlos

    2004-12-01

    Full Text Available In this article we present different samples of housings and small hotels, realised in Spain by Iberdrola company, with installations and equipment from “todo eléctrico’’ housings, domotically conducted. The purpose of this company is to show to Prescriptors, Promoters, Constructors and Fitters, through different visits to the buildings, the advantages that those management systems are bringing to this sector.En este artículo se presentan varios ejemplos de viviendas y pequeños hoteles, realizados en España por la empresa Iberdrola, con instalación y equipamiento de viviendas “todo eléctrico” gestionadas domóticamente. La intención de la empresa era demostrar a los Prescriptores, Promotores, Constructores e Instaladores mediante visitas a los edificios las ventajas aportadas por estos sistema de gestión en el sector.

  11. Residentes de pediatria diante da violência doméstica contra crianças e adolescentes

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    Maria Lúcia de Moraes Bourroul

    2008-12-01

    Full Text Available Buscou-se compreender as percepções de residentes de pediatria diante da violência doméstica contra crianças e adolescentes (VDCA. Realizou-se estudo qualitativo, com 67 residentes, inseridos em nove dos 15 programas existentes no município de São Paulo, com questionários semi-estruturados e entrevistas em profundidade com nove sujeitos. A quase totalidade expressou medo e caracterizou a formação como insuficiente. As falas dos sujeitos sugerem discriminação e estranhamento diante do outro, caracterizando situação onde sociedades diferentes aparecem como ameaçadoras. Diagnosticar VDCA foi a atribuição do pediatra mais reconhecida pelos entrevistados; embora metade deles tenha citado a notificação, poucos notificariam com relatório médico. Há etapas do atendimento da criança sob risco de violência a ser mais bem entendidas. Questões do residente, como o medo, devem ser consideradas para que ele possa reconhecer a criança na sua alteridade e desempenhar melhor seu papel.

  12. Residentes de pediatria diante da violência doméstica contra crianças e adolescentes

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    Maria Lúcia de Moraes Bourroul

    Full Text Available Buscou-se compreender as percepções de residentes de pediatria diante da violência doméstica contra crianças e adolescentes (VDCA. Realizou-se estudo qualitativo, com 67 residentes, inseridos em nove dos 15 programas existentes no município de São Paulo, com questionários semi-estruturados e entrevistas em profundidade com nove sujeitos. A quase totalidade expressou medo e caracterizou a formação como insuficiente. As falas dos sujeitos sugerem discriminação e estranhamento diante do outro, caracterizando situação onde sociedades diferentes aparecem como ameaçadoras. Diagnosticar VDCA foi a atribuição do pediatra mais reconhecida pelos entrevistados; embora metade deles tenha citado a notificação, poucos notificariam com relatório médico. Há etapas do atendimento da criança sob risco de violência a ser mais bem entendidas. Questões do residente, como o medo, devem ser consideradas para que ele possa reconhecer a criança na sua alteridade e desempenhar melhor seu papel.

  13. A divisão de tarefas domésticas entre homens e mulheres no cotidiano do casamento*

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    Bernardo Jablonski

    Full Text Available O presente trabalho visa a investigar como se dá a negociação de tarefas dentro do lar face às novas demandas impostas a reboque do movimento de emancipação feminina e do ingresso maciço das mulheres no mercado de trabalho. Procuramos avaliar atitudes e comportamentos acerca de diversos tópicos relativos ao cotidiano da vida em comum entrevistando 20 membros de casais heterossexuais de classe média, com idades entre 30 e 40 anos, com pelo menos 5 anos de união e ao menos um filho. Entre os principais resultados, destacamos que, apesar da existência de uma dupla jornada de trabalho e das dificuldades demonstradas pelos homens em compartilhar de forma igualitária as tarefas domésticas - recaindo sobre a mulher o peso maior (cuidar da casa e das crianças, fazer compras, arrumar, lavar e passar, etc. - não observamos, como seria esperado, um aumento considerável de conflitos na relação marital.

  14. Writing and social behavior: Dom Obá II in the pages of Rio de Janeiro 19th century newspapers

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    Lilian do Rocio Borba

    2015-02-01

    Full Text Available This article aims to focus on the writings of Candido da Fonseca Galvão (1845-1890, Dom Obá II d’África, as a strategy for visibility and social mobility. Galvão was a free black man during slavery Brazil. Son of a free African of Yoruba origin, he published a series of articles in newspapers of Rio de Janeiro in the late nineteenth century. This case study is theoretically based on historical sociolinguistics in dialogue with studies related to social history, a historiographic trend that uses evidence from various aspects of the diverse agents of everyday history, especially those participating in subordinate roles in history, the so-called “history from below”. The social meaning assigned to the writings by Cândido Galvão is an important element to discuss the use of language as a social behavior (Labov, 2008 [1972], especially the desire for social mobility. The writings of this individual of the nineteenth century witnessed a social behavior deeply connected with the values related to the written practices of the society of that time. By means of participation in writing practices, the historical subject of this research imposed himself as a citizen, constituting the identity of a writing subject.

  15. O caso Hope: sensualidade feminina na vida doméstica e na vida pública

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    Ligia Campos de Cerqueira Lana

    2013-12-01

    Full Text Available No final de 2011, uma campanha publicitária de lingerie, protagonizada por Gisele Bündchen, tornou-se um acontecimento ao ser denunciada pelo governo por contribuir para a manutenção das desigualdades entre homens e mulheres. No enredo da propaganda, a modelo resolve seus problemas domésticos através da sensualidade. Este artigo analisa a estrutura do acontecimento gerado pela denúncia governamental com base em textos veiculados na mídia. O objetivo não é avaliar a campanha publicitária, mas identificar em diversos textos midiáticos a maneira como a sensualidade feminina foi observada na experiência pública. A análise mostra que a condenação da ação do governo se sobrepõe ao debate das questões que envolvem a legitimidade da participação das mulheres na vida pública. Apesar da constante exaltação cultural da sensualidade feminina no Brasil, o caso pouco mobilizou o tema.

  16. Sobre el control convencional en la praxis penal internacional y doméstica de los Derechos Fundamentales

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    Duvi Teixidor

    2013-12-01

    Full Text Available Se trata de una aproximación a la dogmática penal internacional, en el ámbito interamericano y europeo, con especial énfasis en el paradigma normativo asumido en la praxis de derechos humanos. El enfoque discurre desde el principio transversal de imparcialidad a la justificación y aplicación del Derecho Penal Internacional de Derechos humanos, mediante la adopción del espiral hermenéutico. En este plano analítico relacional, se arriba al examen de la teoría del caso asumida en distintos ejemplos que consolidan una jurisprudencia principialista, para la efectiva realización de los derechos fundamentales aquí y ahora (Dasein. A partir de esa expresión de sentido, se hace hincapié en las fases del control de convencionalidad a nivel jurisdiccional doméstico e internacional.

  17. Lithologies, structure and basement-cover relationships in the schist belt of the Dom Feliciano Belt in Uruguay

    Directory of Open Access Journals (Sweden)

    Henri Masquelin

    Full Text Available ABSTRACT: This work is the result of a multiyear effort to use field geology to describe lithologies, to establish contact relationships and to create a sketch of the tectonic evolution of the Meso- to Neoproterozoic metasedimentary successions within the Schist Belt of the Dom Feliciano Belt. This low-grade metamorphic cover rests on the high-grade metamorphic basement of the La China and Las Tetas complexes. This basement is Archean-Paleoproterozoic in age. The Schist Belt is overlapped unconformably by the Barriga Negra formation. The Lavalleja complex and the Barriga Negra formation both deformed together during the D2 deformation event (~ 570 -540 Ma, but the Barriga Negra only partially recorded the D2 transpressive event, whereas the Lavalleja complex was affected by both the D1 tangential event and the D2 event. Event D1 would have developed a fold nappe with vergence to the south. This hypothesis is supported by different structures: (i recumbent and upright folds oriented E-W, (ii subhorizontal mylonitic foliation in marbles (calc-schists, (iii stretching lineations plunging towards the SW in metaconglomerates of the Las Tetas Complex, and (iv a reworking of the subhorizontal foliation parallel to the Sarandí del Yí strike-slip shear zone.

  18. Wave breaking in the surf zone and deep-water in a non-hydrostatic RANS model. Part 2: Turbulence and mean circulation

    Science.gov (United States)

    Derakhti, Morteza; Kirby, James T.; Shi, Fengyan; Ma, Gangfeng

    2016-11-01

    Field-scale modeling of wave-breaking-induced turbulence and mean circulation is still challenging. Although Boussinesq-type models have been successfully used to study field-scale wave transformation and wave-breaking-driven circulation, they cannot provide turbulence or the vertical structure of the velocity field. In addition, the applicability of such models is limited to shallow water. In Part 1 (Derakhti et al., 2016b) of this study, we showed that the non-hydrostatic σ-coordinate RANS model NHWAVE, as described by Derakhti et al. (2016a), accurately predicts organized wave motions and total wave-breaking-induced energy dissipation from deep-water up to the swash zone using a few vertical σ-layers. In this paper, our goal is to examine what level of detail of wave-breaking-induced turbulence and mean circulation, both in depth- and steepness-limited breaking waves, can be reproduced by NHWAVE. Further, effects of modeled turbulent eddy viscosity on the predicted time-averaged velocity distribution is discussed. We establish that NHWAVE is capable of predicting the structure of the mean velocity and vorticity fields including large-scale breaking-induced coherent vortices in deep-water breaking events; where the absence of turbulence-induced eddy viscosity results in the overprediction of the velocity and vorticity field in the breaking region. We show that NHWAVE reduces the required CPU time up to two orders of magnitude in comparison with a comparable VOF-based simulation.

  19. Dependence of solvent quality on the composition of copolymers: experiment and theory for solutions of P(MMA-ran-t-BMA) in toluene and in chloroform.

    Science.gov (United States)

    Bercea, Maria; Wolf, Bernhard A

    2015-01-21

    The interaction of toluene with P(MMA-ran-t-BMA) and with the corresponding homopolymers was determined via vapor pressure measurements at 30, 50 and 70 °C. A unified thermodynamic approach served for the modeling of the results. It is capable of describing the behavior of the different solutions by means of two adjustable parameters, one representing the effective number of solvent segments and the other accounting for the interactions between the components. The solvent quality of toluene passes a maximum, a minimum and another maximum upon an increase of the t-BMA content of the copolymer at all temperatures. A similar behavior is discernable from vapor pressure data of chloroform published for the same copolymers. The heats of mixing for toluene depend strongly on temperature; at 50 °C they are all endothermal with the exception of PMMA, for which the value obtained from vapor pressures at 30 °C agrees very well with published caloric data.

  20. Diplomacia e política doméstica: a lógica dos jogos de dois níveis

    Directory of Open Access Journals (Sweden)

    Robert D. Putnam

    2010-06-01

    Full Text Available A política doméstica e as relações internacionais com freqüência são inextricavelmente vinculadas; todavia, as teorias existentes (particularmente as estatocêntricas não levam adequadamente em considerações tais vínculos. Quando os líderes nacionais devem obter as ratificações (formais ou informais dos membros de seus parlamentos para um acordo internacional, seus comportamentos em negociações refletem os imperativos simultâneos tanto de um jogo de política doméstica quanto de um jogo de política internacional. Usando exemplos de cúpulas econômicas ocidentais, das negociações do Canal do Panamá e do Tratado de Versalhes, dos programas de estabilização do Fundo Monetário Internacional, da Comunidade Européia e de muitos outros contextos diplomáticos, o artigo oferece uma teoria da ratificação. Ele enfatiza o papel das preferências, coalizões, instituições e práticas domésticas, das estratégias e táticas dos negociadores, da incerteza, das reverberações domésticas das pressões externas e o papel dos interesses do negociador-chefe. Essa teoria de "jogos de dois níveis" também pode ser aplicável a muitos outros fenômenos políticos, tais como a dependência, os comitês legislativos e as coalizões multipartidárias.