WorldWideScience

Sample records for radiation 280-315 nm

  1. UVR-induced photosynthetic inhibition dominates over DNA damage in marine dinoflagellates exposed to fluctuating solar radiation regimes

    NARCIS (Netherlands)

    Helbling, E. Walter; Buma, Anita G. J.; van de Poll, Willem; Fernandez Zenoff, M. Veronica; Villafane, Virginia E.

    2008-01-01

    The combined effect of solar radiation (UV-B (280-315 nm), UWA (315-400 nm) and PAR (400-700 nm)) and vertical mixing (i.e., fluctuating radiation regimes) on the marine dinoflagellates Gymnodinium chlorophorum, Heterocapsa triquetra and Prorocentrum micans was investigated during the austral spring

  2. Human exposure to ultraviolet radiation

    International Nuclear Information System (INIS)

    Bernhardt, J.H.; Matthes, R.

    1987-01-01

    Ultraviolet radiation is that part of the electromagnetic spectrum located between the softest ionizing radiation and visible radiation. The lower limit of 100 nm is equivalent to photon energies of 12.4 eV, which corresponds approximately to the limit for the production of ionization in biologically important materials. A historical subdividing of the UV-region takes some of the biological effects into account. In this arrangement the range 400-315 nm, the so-called black light region, is called UV-A. In this wavelength region, fluorescence can be induced in many substances. UV-B covers the range 315-280 nm (the skin erythemal region). Most of the biologically active and potentially harmful UV from the sun reaching the surface of the earth is part of this spectral region. UV-C includes the radiation of wavelengths less than 280 nm (the germicidal region). It should be noted that this classification is somewhat arbitrary, and today it is more usual to evaluate the biological effectiveness of the whole UV-range from 200 to 400 nm

  3. Response of sugar beet plants to ultraviolet-B (280-320 nm) radiation and Cercospora leaf spot disease

    International Nuclear Information System (INIS)

    Panagopoulos, I.; Bornman, J.F.; Björn, L.O.

    1992-01-01

    Sugar beet (Beta vulgaris L.) plants injected with Cercospora beticola Sacc. as well as non-infected plants were grown under visible light with or without ultraviolet-B (UV-B, 280-320 nm) radiation for 40 days. An interaction between UV-B radiation and Cercospora leaf spot disease was observed, resulting in a large reduction in leaf chlorophyll content, dry weight of leaf laminae, petioles and storage roots. Lipid peroxidation in leaves also increased the most under the combined treatments. This was also true for ultraweak luminescence from both adaxial and abaxial leaf surfaces. However, no correlation between lipid peroxidation and ultraweak luminescence was observed. Ultraviolet-B radiation given alone appeared to have either a stimulating effect, giving an increase in dry weight of laminac and reducing lipid peroxidation, or no effect. This lack of effect was seen in the absence of change in dry weight of storage roots and chlorophyll content relative to controls. The study demonstrated a harmful interaction between UV-B radiation and Cercospora leaf spot disease on sugar beet

  4. Evaluation of DNA dosimetry to assess ozone-mediated variability of biologically harmful radiation in Antarctica

    NARCIS (Netherlands)

    George, AL; Peat, HJ; Buma, AGJ

    In this study we investigated the use of a DNA dosimeter to accurately measure changes in ultraviolet B radiation (UVBR; 280-315 nm) under Antarctic ozone hole conditions. Naked DNA solution in quartz tubes was exposed to ambient solar radiation at Rothera Research Station, Antarctica, between

  5. Ocean acidification alters the photosynthetic responses of a coccolithophorid to fluctuating ultraviolet and visible radiation.

    Science.gov (United States)

    Jin, Peng; Gao, Kunshan; Villafañe, Virginia E; Campbell, Douglas A; Helbling, E Walter

    2013-08-01

    Mixing of seawater subjects phytoplankton to fluctuations in photosynthetically active radiation (400-700 nm) and ultraviolet radiation (UVR; 280-400 nm). These irradiance fluctuations are now superimposed upon ocean acidification and thinning of the upper mixing layer through stratification, which alters mixing regimes. Therefore, we examined the photosynthetic carbon fixation and photochemical performance of a coccolithophore, Gephyrocapsa oceanica, grown under high, future (1,000 μatm) and low, current (390 μatm) CO₂ levels, under regimes of fluctuating irradiances with or without UVR. Under both CO₂ levels, fluctuating irradiances, as compared with constant irradiance, led to lower nonphotochemical quenching and less UVR-induced inhibition of carbon fixation and photosystem II electron transport. The cells grown under high CO₂ showed a lower photosynthetic carbon fixation rate but lower nonphotochemical quenching and less ultraviolet B (280-315 nm)-induced inhibition. Ultraviolet A (315-400 nm) led to less enhancement of the photosynthetic carbon fixation in the high-CO₂-grown cells under fluctuating irradiance. Our data suggest that ocean acidification and fast mixing or fluctuation of solar radiation will act synergistically to lower carbon fixation by G. oceanica, although ocean acidification may decrease ultraviolet B-related photochemical inhibition.

  6. Environment and health: 3. Ozone depletion and ultraviolet radiation

    International Nuclear Information System (INIS)

    De Gruijl, F.R.; Van der Leun, J.C.

    2000-01-01

    Ultraviolet radiation from the sun is responsible for a variety of familiar photochemical reactions, including photochemical smog, bleaching of paints and decay of plastics. Conjugated bonds in organic molecules such as proteins and DNA absorb the UV radiation, which can damage these molecules. By a fortunate evolutionary event, the oxygen produced by photosynthesis forms a filter in the outer reaches of our atmosphere that absorbs the most energetic and harmful UV radiation, with wavelengths below 240 nm (in the UVC band [wavelength 100-280 nm]). In the process, the oxygen molecules split up and recombine to form ozone (Fig. 1). This ratified ozone layer (spread out between 10 and 50 Ion in the stratosphere but only 3 mm thick were it compressed at ground level) in turn efficiently absorbs UV radiation of higher wavelengths (tip to about 310 nm). A part of the UV radiation in the UVB band (wavelength 280-315 nm) still reaches ground level and is absorbed in sufficient amounts to have deleterious effects on cells. The less energetic radiation in the UVA band (wavelength 315-400 nm, bordering the visible band [wavelength 400-800 nm]) is not absorbed by ozone and reaches ground level without much attenuation through a clear atmosphere (i.e., no clouds, no air pollution). Although not completely innocuous, the UVA radiation in sunlight is much less photochemically active and therefore generally less harmful than UVB radiation. Life on earth has adapted itself to the UV stress, particularly UVB stress, fbr example by forming protective UV-absorbing surface layers, by repairing cell damage or by replacing damaged cells entirely. Human skin shows all of these adaptive features. Our eyes are less well adapted, but dicy, are shielded by the brows and by squinting. (author)

  7. Effects of enhanced UV-B radiation on nitrogen fixation in arctic ecosystems.

    NARCIS (Netherlands)

    Solheim, B.; Zielke, M.; Bjerke, J.W.; Rozema, J.

    2006-01-01

    Recent global climate models predict a further significant loss of ozone in the next decades, with up to 50% depletion of the ozone layer over large parts of the Arctic resulting in an increase in ultraviolet-B radiation (UV-B) (280-315 nm) reaching the surface of the Earth. The percentage of total

  8. Interacciones de las radiaciones electromagnéticas y especies reactivas del oxígeno sobre la piel Interactions of electromagnetic radiations and reactive oxygen species on skin

    Directory of Open Access Journals (Sweden)

    A M Ferramola de Sancovich

    2006-06-01

    Full Text Available La energía radiante abarca todo el espectro electromagnético y proviene de la fusión en el sol, de 4 núcleos de hidrógeno en uno de helio. Las radiaciones electromagnéticas tienen características de ondas, con la velocidad de la luz (c y difieren en sus longitudes de ondas (λ. La energía lumínica es transmitida en unidades individuales o fotones: E = h c/λ así, los fotones de menores λs son los de mayor energía. Las radiaciones ultravioletas (UV (λs de 200 - 400 nm pueden dividirse: UVA (λs 315 - 400 nm; UVB (λs 280 - 315 nm y UVC (λs The energy of electromagnetic radiation is derived from the fusion in the sun of four hydrogen nuclei to form a helium nucleus. The sun radiates energy representing the entire electromagnetic spectrum. Light is a form of electromagnetic radiation. All electromagnetic radiation has wave characteristics and travels at the same speed (c: speed of light. But radiations differ in wavelength (λ. Light energy is transmitted not in a continuum stream but only in individual units or photons: E = h c/λ. Short wave light is more energetic than photons of light of longer wavelength. Ultraviolet radiations (UV (λs 200 - 400 nm can be classified in UVA (λs 315 - 400 nm.; UVB (λs 280 - 315 nm and UVC (λs < 280 nm. UVB and UVC are the most significant UV radiations to induce biological responses. Electromagnetic radiations on molecular oxygen lead to several reactive products known as Reactive Oxygen Species (ROS. High O2 content in biological systems promotes ROS synthesis. If ROS are not controlled by endogenous antioxidants, cell redox status is affected and tissue damage is produced ("oxidative stress". ROS induce lipid peroxidation, protein cross-linking, enzyme inhibition, loss of integrity and function of plasmatic and mitochondrial membranes conducing to inflammation, aging, carcinogenesis and cell death. While infra-red radiations lead to noticeable tissue temperature conducing to severe burns, UVA

  9. Ocular effects of ultraviolet radiation from 295 to 365 nm

    International Nuclear Information System (INIS)

    Pitts, D.G.; Cullen, A.P.; Hacker, P.D.

    1977-01-01

    A 5,000 watt Xe--Hg source and a double monochromator were used to produce 6.6 nm full band-pass ultraviolet (UV) radiation. Pigmented rabbit eyes were exposed to the 6.6 nm band-pass UV radiant energy in 5 nm steps from 295 to 320 nm and at random intervals above 320 nm. Corneal and lenticular damage was assessed and classified with a biomicroscope. Corneal threshold radiant exposure (Hc) rose very rapidly from 0.022 Jcm -2 at 300 nm to 10.99 Jcm -2 at 335 nm. Radiant exposures exceeding 2 x Hc resulted in irreversible corneal damage. Lenticular damage was limited to wavebands above 295 nm. The action spectrum for the lens began at 295 nm and extended to about 315 nm. Permanent lenticular damage occurred at radiant exposure levels approximately twice the threshold for lenticular radiant exposure. The importance in establishing both corneal and lenticular damage criteria is emphasized

  10. Photosynthesis, growth, and ultraviolet irradiance absorbance of Cucurbita pepo L. leaves exposed to ultraviolet-B radiation (280 to 315 nm)

    International Nuclear Information System (INIS)

    Sisson, W.B.

    1981-01-01

    Net photosynthesis, growth, and ultraviolet (uv) radiation absorbance were determined for the first leaf of Cucurbita pepo L. exposed to two levels of uv-B irradiation and a uv-B radiation-free control treatment. Absorbance by extracted flavonoid pigments and other uv-B radiation-absorbing compounds from the first leaves increased with time and level of uv-B radiation impinging on leaf surfaces. Although absorbance of uv-B radiation by extracted pigments increased substantially, uv-B radiation attenuation apparently was insufficient to protect completely the photosynthetic apparatus or leaf growth processes. Leaf expansion was repressed by daily exposure to 1365 Joules per meter per day of biologically effective uv-B radiation by not by exposure to 660 Joules per meter per day. Photosynthesis measured through ontogenesis of the first leaf was depressed by both uv-B radiation treatments. Repression of photosynthesis by uv-B radiation was especially evident during the ontogenetic period of maximum photosynthetic activity

  11. Autonomous portable solar ultraviolet spectroradiometer (APSUS) - a new CCD spectrometer system for localized, real-time solar ultraviolet (280-400 nm) radiation measurement.

    Science.gov (United States)

    Hooke, Rebecca; Pearson, Andy; O'Hagan, John

    2014-01-01

    Terrestrial solar ultraviolet (UV) radiation has significant implications for human health and increasing levels are a key concern regarding the impact of climate change. Monitoring solar UV radiation at the earth's surface is therefore of increasing importance. A new prototype portable CCD (charge-coupled device) spectrometer-based system has been developed that monitors UV radiation (280-400 nm) levels at the earth's surface. It has the ability to deliver this information to the public in real time. Since the instrument can operate autonomously, it is called the Autonomous Portable Solar Ultraviolet Spectroradiometer (APSUS). This instrument incorporates an Ocean Optics QE65000 spectrometer which is contained within a robust environmental housing. The APSUS system can gather reliable solar UV spectral data from approximately April to October inclusive (depending on ambient temperature) in the UK. In this study the new APSUS unit and APSUS system are presented. Example solar UV spectra and diurnal UV Index values as measured by the APSUS system in London and Weymouth in the UK in summer 2012 are shown. © 2014 Crown copyright. Photochemistry and Photobiology © 2014 The American Society of Photobiology. This article is published with the permission of the Controller of HMSO and the Queen's Printer for Scotland and Public Health England.

  12. In vivo activation of human immunodeficiency virus type 1 long terminal repeat by UV type A (UV-A) light plus psoralen and UV-B light in the skin of transgenic mice

    OpenAIRE

    Morrey, John D; Bourn, S M; Bunch, T D; Jackson, M K; Sidwell, R W; Barrows, L R; Daynes, R A; Rosen, C A

    1991-01-01

    UV irradiation has been shown to activate the human immunodeficiency virus type 1 (HIV-1) long terminal repeat (LTR) in cell culture; however, only limited studies have been described in vivo. UV light has been categorized as UV-A (400 to 315 nm), -B (315 to 280 nm), or -C (less than 280 nm); the longer wavelengths are less harmful but more penetrative. Highly penetrative UV-A radiation constitutes the vast majority of UV sunlight reaching the earth's surface but is normally harmless. UV-B ir...

  13. NH4+ enrichment and UV radiation interact to affect the photosynthesis and nitrogen uptake of Gracilaria lemaneiformis (Rhodophyta).

    Science.gov (United States)

    Xu, Zhiguang; Gao, Kunshan

    2012-01-01

    Solar ultraviolet radiation (UVR, 280-400 nm) is known to inhibit the photosynthesis of macroalgae, whereas nitrogen availability may alter the sensitivity of the algae to UVR. Here, we show that UV-B (280-315 nm) significantly reduced the net photosynthetic rate of Gracilaria lemaneiformis. This inhibition was alleviated by enrichment with ammonia, which also caused a decrease in dark respiration. The presence of both UV-A (315-400 nm) and UV-B stimulated the accumulation of UV-absorbing compounds. However, this stimulation was not affected by enrichment with ammonia. The content of phycoerythrin (PE) was increased by the enrichment of ammonia only in the absence of UVR. Ammonia uptake and the activity of nitrate reductase were repressed by UVR. However, exposure to UVR had an insignificant effect on the rate of nitrate uptake. In conclusion, increased PE content associated with ammonia enrichment played a protective role against UVR in this alga, and UVR differentially affected the uptake of nitrate and ammonia. Copyright © 2011 Elsevier Ltd. All rights reserved.

  14. DNA Damage and Repair in Plants under Ultraviolet and Ionizing Radiations

    Science.gov (United States)

    Gill, Sarvajeet S.; Gill, Ritu; Jha, Manoranjan; Tuteja, Narendra

    2015-01-01

    Being sessile, plants are continuously exposed to DNA-damaging agents present in the environment such as ultraviolet (UV) and ionizing radiations (IR). Sunlight acts as an energy source for photosynthetic plants; hence, avoidance of UV radiations (namely, UV-A, 315–400 nm; UV-B, 280315nm; and UV-C, important target for UV-B induced damage. On the other hand, IR causes water radiolysis, which generates highly reactive hydroxyl radicals (OH•) and causes radiogenic damage to important cellular components. However, to maintain genomic integrity under UV/IR exposure, plants make use of several DNA repair mechanisms. In the light of recent breakthrough, the current minireview (a) introduces UV/IR and overviews UV/IR-mediated DNA damage products and (b) critically discusses the biochemistry and genetics of major pathways responsible for the repair of UV/IR-accrued DNA damage. The outcome of the discussion may be helpful in devising future research in the current context. PMID:25729769

  15. Ultraviolet radiation and the snow alga Chlamydomonas nivalis (Bauer) Wille.

    Science.gov (United States)

    Gorton, Holly L; Vogelmann, Thomas C

    2003-06-01

    Aplanospores of Chlamydomonas nivalis are frequently found in high-altitude, persistent snowfields where they are photosynthetically active despite cold temperatures and high levels of visible and ultraviolet (UV) radiation. The goals of this work were to characterize the UV environment of the cells in the snow and to investigate the existence and localization of screening compounds that might prevent UV damage. UV irradiance decreased precipitously in snow, with UV radiation of wavelengths 280-315 nm and UV radiation of wavelengths 315-400 nm dropping to 50% of incident levels in the top 1 and 2 cm, respectively. Isolated cell walls exhibited UV absorbance, possibly by sporopollenin, but this absorbance was weak in images of broken or plasmolyzed cells observed through a UV microscope. The cells also contained UV-absorbing cytoplasmic compounds, with the extrachloroplastic carotenoid astaxanthin providing most of the screening. Additional screening compound(s) soluble in aqueous methanol with an absorption maximum at 335 nm played a minor role. Thus, cells are protected against potentially high levels of UV radiation by the snow itself when they live several centimeters beneath the surface, and they rely on cellular screening compounds, chiefly astaxanthin, when located near the surface where UV fluxes are high.

  16. Photolysis of butenedial at 193, 248, 280, 308, 351, 400, and 450 nm

    Science.gov (United States)

    Tang, Yongxin; Zhu, Lei

    2005-06-01

    We have studied the photolysis of butenedial at 193, 248, 280, 308, 351, 400, and 450 nm by using laser photolysis combined with cavity ring-down spectroscopy. The HCO radical is a photodissociation product at 193 and 248 nm. The corresponding HCO quantum yields are 0.55 ± 0.07 and 0.12 ± 0.01, independent of butenedial pressure and nitrogen buffer gas pressure. Absorption cross-sections of butenedial are (6.88 ± 0.39) × 10 -18 and (3.62 ± 0.69) × 10 -19 cm 2 at 193 and 248 nm. The end-products from the photolysis of butenedial at 193, 248, 308, and 351 nm were measured by FTIR. Acrolein and 3H-furan-2-one were observed and their yields have been estimated.

  17. Mitotic effects of monochromatic ultraviolet radiation at 225, 265, and 280 nm on eleven stages of the cell cycle of the grasshopper neuroblast in culture. I. Overall retardation from the stage irradiated to nuclear membrane breakdown

    International Nuclear Information System (INIS)

    Carlson, J.G.

    1976-01-01

    Neuroblasts of Chortophaga viridifasciata (DeGeer) in culture were exposed to different doses of 225, 265, or 280 nm ultraviolet radiations at 11 different stages and substages of the mitotic cycle and individually selected cells were timed to breakdown of the nuclear membrane. Comparisons of the effectiveness of different wavelengths on the different stages were based on the dose that reduced the cell progression rate to 67 percent of normal (D 67 ) and the slope of the regression line, i.e., the control to treated time (C/T) ratio change/erg/mm 2 at the D 67 level. Cells of the prereplication period (metaphase + anaphase + early telophase) and the S phase (middle and late telophase + interphase + very early prophase) are equally sensitive to uv and contrast sharply with the much lower sensitivity of those in the postreplication period (early and middle prophase). This can best be interpreted if chromosomal DNA is the chromophore for uv-induced mitotic retardation. Cells in the prereplication period at exposure show no wavelength effect. In the S phase all stages except middle telophase and all stages combined are significantly more sensitive to 265 and 280 nm than to 225 nm. Of the postreplication stages, early prophase is retarded significantly more by 280 than by 225 or 265 nm. The C/T ratio/erg/mm 2 is greater after exposure to 265 nm at all prereplication and replication stages, but exhibits no consistent wavelength pattern during the postreplication period. Evidence based on the orientation of the neuroblast with respect to the uv-source suggests that the chromophore for mitotic retardation does not reside within the centrosome and related structures, but may be present, at least partly, in the nucleolus

  18. Effects of emollients on ultraviolet-radiation-induced erythema of the skin

    International Nuclear Information System (INIS)

    Schleider, N.R.; Moskowitz, R.S.; Cort, D.H.; Horwitz, S.N.; Frost, P.

    1979-01-01

    Several commonly used emollients were studied as to their effectiveness in absorbing and filtering erythema-causing ultraviolet radiation in the 280 to 315 nm range (UVB). Planter's Peanut Oil (Standard Brands) and Mazola Corn Oil (Best Foods Inc.) had no effect; Alpha Keri Bath Oil (Westwood Pharmaceuticals), mineral oil, and Johnson's Baby Oil (Johnson and Johnson Co) had minimal effects. Vaseline Petroleum Jelly (Chesebrough-Ponds Inc.), petrolatum, and hydrophilic ointment substantially reduced the erythema that was induced by exposure to low doses of UVB radiation. Therefore, these emollients may interfere with the therapeutic effects of the ultraviolet radiation component of the Goeckerman treatment when it is administered in low doses to patients with psoriasis

  19. NH4+ enrichment and UV radiation interact to affect the photosynthesis and nitrogen uptake of Gracilaria lemaneiformis (Rhodophyta)

    International Nuclear Information System (INIS)

    Xu Zhiguang; Gao Kunshan

    2012-01-01

    Highlights: ► Inhibition induced by UVR is alleviated with the enrichment of ammonia. ► Phycoerythrin plays a key protective role against UVR at higher level of ammonia. ► Effect of UVR on the uptakes of nitrate and ammonia is different. - Abstract: Solar ultraviolet radiation (UVR, 280–400 nm) is known to inhibit the photosynthesis of macroalgae, whereas nitrogen availability may alter the sensitivity of the algae to UVR. Here, we show that UV-B (280315 nm) significantly reduced the net photosynthetic rate of Gracilaria lemaneiformis. This inhibition was alleviated by enrichment with ammonia, which also caused a decrease in dark respiration. The presence of both UV-A (315–400 nm) and UV-B stimulated the accumulation of UV-absorbing compounds. However, this stimulation was not affected by enrichment with ammonia. The content of phycoerythrin (PE) was increased by the enrichment of ammonia only in the absence of UVR. Ammonia uptake and the activity of nitrate reductase were repressed by UVR. However, exposure to UVR had an insignificant effect on the rate of nitrate uptake. In conclusion, increased PE content associated with ammonia enrichment played a protective role against UVR in this alga, and UVR differentially affected the uptake of nitrate and ammonia.

  20. Unraveling the pathogenesis of polymorphous light eruption : a comparative study in patients with polymorphous light eruption and healthy individuals

    NARCIS (Netherlands)

    Essers-Kölgen, Wendy

    2003-01-01

    Ultraviolet (UV) radiation, especially UV-B (280-315 nm), can suppress cellular immunity, thereby preventing the occurrence of a disruptive immune reaction against UV-modified organic molecules (e.g. DNA, proteins) whenever the skin is exposed to UV-B radiation. An inadequate immunosuppression could

  1. Absolute cross sections for emission of 284.7-nm (Hg II) and 479.7-nm (Hg III) radiation in electron--mercury-ion collisions

    International Nuclear Information System (INIS)

    Phaneuf, R.A.; Taylor, P.O.; Dunn, G.H.

    1976-01-01

    Crossed beams of electrons and Hg + ions have been used to measure absolute cross sections for emission of 284.7-nm radiation, resulting from excitation of a predominantly ground-state Hg + target to the 7s 2 S 1 / 2 state. Values range from 3 x 10 -17 cm 2 near threshold, where the cross section is strongly peaked, to 1.3 x 10 -18 cm 2 at 280 eV. Also reported are some measurements of emission of 479.7-nm (Hg III) radiation, resulting from electron impact on both Hg + and Hg ++ targets. Cross sections range from approximately 5 x 10 -19 to 5 x 10 -20 cm 2 , and in the case of electron-Hg ++ collisions, are more than an order of magnitude smaller than predicted by an available semiclassical binary-encounter calculation

  2. Mean Annual UV-B Irradiance

    Data.gov (United States)

    U.S. Environmental Protection Agency — Ultraviolet-B (UV-B) radiation is the most energetic part of sunlight reaching the Earth's surface (wavelength region is 280 to 315 nm), and it has been shown to...

  3. Interactions of electromagnetic radiations and reactive oxygen species on skin

    International Nuclear Information System (INIS)

    Ferramola de Sancovich, A.M.; Sancovich, H.A. . E- mail: ferramol@qb.fcen.uba.ar

    2006-01-01

    The energy of electromagnetic radiation is derived from the fusion in the sun of four hydrogen nuclei to form a helium nucleus. The sun radiates energy representing the entire electromagnetic spectrum. Light is a form of electromagnetic radiation: all electromagnetic radiation has wave characteristics and travels at the same speed (c: speed of light). But radiations differ in wavelength (λ). Light energy is transmitted not in a continuum stream but only in individual units or photons: E = h c / λ. Short wave light is more energetic than photons of light of longer wavelength. Ultraviolet radiations (UV) (λ s 200- 400 nm) can be classified in UV A (λ s 315 - 400 nm.); UV B (λ s 280 - 315 nm) and UV C (λ s 2 content in biological systems promotes ROS synthesis. If ROS are not controlled by endogenous antioxidants, cell redox status is affected and tissue damage is produced ('oxidative stress'). ROS induce lipid peroxidation, protein cross-linking, enzyme inhibition, loss of integrity and function of plasmatic and mitochondrial membranes conducing to inflammation, aging, carcinogenesis and cell death. While infra-red radiations lead to noticeable tissue temperature conducing to severe burns, UV A and UV B undercover react with skin chromophores producing photochemical alterations involved in cellular aging and cancer induction. As UV radiations can reach cellular nucleus, DNA can be damage. Human beings need protection from the damaging sunbeams. This is a very important concern of public health. While humans need to protect their skin with appropriate clothing and/or by use of skin sun blocks of broad spectrum, some bacteria that are extensively exposed to sunlight have developed genomic evolution (plasmid-encoded DNA repair system) which confers protection from the damaging effect of UV radiation. (author) [es

  4. Manipulating Sensory and Phytochemical Profiles of Greenhouse Tomatoes Using Environmentally Relevant Doses of Ultraviolet Radiation.

    Science.gov (United States)

    Dzakovich, Michael P; Ferruzzi, Mario G; Mitchell, Cary A

    2016-09-14

    Fruits harvested from off-season, greenhouse-grown tomato plants have a poor reputation compared to their in-season, garden-grown counterparts. Presently, there is a gap in knowledge with regard to the role of UV-B radiation (280-315 nm) in determining greenhouse tomato quality. Knowing that UV-B is a powerful elicitor of secondary metabolism and not transmitted through greenhouse glass and some greenhouse plastics, we tested the hypothesis that supplemental UV-B radiation in the greenhouse will impart quality attributes typically associated with garden-grown tomatoes. Environmentally relevant doses of supplemental UV-B radiation did not strongly affect antioxidant compounds of fruits, although the flavonol quercetin-3-O-rutinoside (rutin) significantly increased in response to UV-B. Physicochemical metrics of fruit quality attributes and consumer sensory panels were used to determine if any such differences altered consumer perception of tomato quality. Supplemental UV-A radiation (315-400 nm) pre-harvest treatments enhanced sensory perception of aroma, acidity, and overall approval, suggesting a compelling opportunity to environmentally enhance the flavor of greenhouse-grown tomatoes. The expression of the genes COP1 and HY5 were indicative of adaptation to UV radiation, which explains the lack of marked effects reported in these studies. To our knowledge, these studies represent the first reported use of environmentally relevant doses of UV radiation throughout the reproductive portion of the tomato plant life cycle to positively enhance the sensory and chemical properties of fruits.

  5. Sunlight suppressing rejection of 280- to 320-nm UV-radiation-induced skin tumors in mice

    International Nuclear Information System (INIS)

    Morison, W.L.; Kelley, S.P.

    1985-01-01

    Repeated exposure of female C3H/HeNCR- mice to sunlight prevented the normal immunologic rejection of a UV-induced tumor. This systemic immunologic alteration was transferred to syngeneic lethally X-irradiated animals with lymphoid cells from mice exposed to sunlight. The lymphoid cells also were able to suppress the capacity of lymphoid cells from normal animals to reject a UV-induced tumor. The 295- to 320-nm wave band appeared to be responsible for this immunosuppressive effect of sunlight because suppression was prevented by filtration of the radiation through Mylar and by application of a sunscreen containing para-aminobenzoic acid. These observations may have importance in understanding the pathogenesis of sunlight-induced skin cancer in humans

  6. UVBR-induced DNA damage in natural marine picoplankton assemblages in the tropical Atlantic Ocean

    NARCIS (Netherlands)

    Boelen, P; de Boer, MK; Kraay, GW; Veldhuis, MJW; Buma, AGJ

    2000-01-01

    UVBR (ultraviolet-B radiation: 280 to 315 nm)-induced DNA damage, measured as cyclobutane pyrimidine dimers (CPDs), was determined in size fractions of natural populations of bacterio- and phytoplankton collected in marine tropical waters. Mean biologically effective UVBR doses in the wind-mixed

  7. Solar Irradiance Changes and Phytoplankton Productivity in Earth's Ocean Following Astrophysical Ionizing Radiation Events

    Science.gov (United States)

    Neale, Patrick J.; Thomas, Brian C.

    2016-04-01

    Two atmospheric responses to simulated astrophysical ionizing radiation events significant to life on Earth are production of odd-nitrogen species, especially NO2, and subsequent depletion of stratospheric ozone. Ozone depletion increases incident short-wavelength ultraviolet radiation (UVB, 280-315 nm) and longer (>600 nm) wavelengths of photosynthetically available radiation (PAR, 400-700 nm). On the other hand, the NO2 haze decreases atmospheric transmission in the long-wavelength UVA (315-400 nm) and short-wavelength PAR. Here, we use the results of previous simulations of incident spectral irradiance following an ionizing radiation event to predict changes in terran productivity focusing on photosynthesis of marine phytoplankton. The prediction is based on a spectral model of photosynthetic response, which was developed for the dominant genera in central regions of the ocean (Synechococcus and Prochlorococcus), and on remote-sensing-based observations of spectral water transparency, temperature, wind speed, and mixed layer depth. Predicted productivity declined after a simulated ionizing event, but the effect integrated over the water column was small. For integrations taking into account the full depth range of PAR transmission (down to 0.1% of utilizable PAR), the decrease was at most 2-3% (depending on strain), with larger effects (5-7%) for integrations just to the depth of the surface mixed layer. The deeper integrations were most affected by the decreased utilizable PAR at depth due to the NO2 haze, whereas shallower integrations were most affected by the increased surface UV. Several factors tended to dampen the magnitude of productivity responses relative to increases in surface-damaging radiation, for example, most inhibition in the modeled strains is caused by UVA and PAR, and the greatest relative increase in damaging exposure is predicted to occur in the winter when UV and productivity are low.

  8. Differential response of radish plants to supplemental ultraviolet-B radiation under varying NPK levels: chlorophyll fluorescence, gas exchange and antioxidants.

    Science.gov (United States)

    Singh, Suruchi; Kumari, Rima; Agrawal, Madhoolika; Agrawal, Shashi Bhushan

    2012-07-01

    Current and projected increases in ultraviolet-B (UV-B; 280-315 nm) radiation may alter crop growth and yield by modifying the physiological and biochemical functions. This study was conducted to assess the possibility of alleviating the negative effects of supplemental UV-B (sUV-B; 7.2 kJ m⁻² day⁻¹; 280-315 nm) on radish (Raphanus sativus var Pusa Himani) by modifying soil nitrogen (N), phosphorus (P) and potassium (K) levels. The N, P and K treatments were recommended dose of N, P and K, 1.5 times recommended dose of N, P and K, 1.5 times recommended dose of N and 1.5 times recommended dose of K. Plants showed variations in their response to UV-B radiation under varying soil NPK levels. The minimum damaging effects of sUV-B on photosynthesis rate and stomatal conductance coupled with minimum reduction in chlorophyll content were recorded for plants grown at recommended dose of NPK. Flavonoids increased under sUV-B except in plants grown at 1.5 times recommended dose of N. Lipid peroxidation (LPO) also increased in response to sUV-B at all NPK levels with maximum at 1.5 times recommended dose of K and minimum at recommended dose of NPK. This study revealed that sUV-B radiation negatively affected the radish plants by reducing the photosynthetic efficiency and increasing LPO. The plants grown at 1.5 times recommended dose of NPK/N/K could not enhance antioxidative potential to the extent as recorded at recommended dose of NPK and hence showed more sensitivity to sUV-B. Copyright © Physiologia Plantarum 2012.

  9. The role of coccoliths in protecting Emiliania huxleyi against stressful light and UV radiation

    Science.gov (United States)

    Xu, Juntian; Bach, Lennart T.; Schulz, Kai G.; Zhao, Wenyan; Gao, Kunshan; Riebesell, Ulf

    2016-08-01

    Coccolithophores are a group of phytoplankton species which cover themselves with small scales (coccoliths) made of calcium carbonate (CaCO3). The reason why coccolithophores form these calcite platelets has been a matter of debate for decades but has remained elusive so far. One hypothesis is that they play a role in light or UV protection, especially in surface dwelling species like Emiliania huxleyi, which can tolerate exceptionally high levels of solar radiation. In this study, we tested this hypothesis by culturing a calcified and a naked strain under different light conditions with and without UV radiation. The coccoliths of E. huxleyi reduced the transmission of visible radiation (400-700 nm) by 7.5 %, that of UV-A (315-400 nm) by 14.1 % and that of UV-B (280-315 nm) by 18.4 %. Growth rates of the calcified strain (PML B92/11) were about 2 times higher than those of the naked strain (CCMP 2090) under indoor constant light levels in the absence of UV radiation. When exposed to outdoor conditions (fluctuating sunlight with UV radiation), growth rates of calcified cells were almost 3.5 times higher compared to naked cells. Furthermore, the relative electron transport rate was 114 % higher and non-photochemical quenching (NPQ) was 281 % higher in the calcified compared to the naked strain, implying higher energy transfer associated with higher NPQ in the presence of calcification. When exposed to natural solar radiation including UV radiation, the maximal quantum yield of photosystem II was only slightly reduced in the calcified strain but strongly reduced in the naked strain. Our results reveal an important role of coccoliths in mitigating light and UV stress in E. huxleyi.

  10. Photosynthetic Performance of the Red Alga Pyropia haitanensis During Emersion, With Special Reference to Effects of Solar UV Radiation, Dehydration and Elevated CO2 Concentration.

    Science.gov (United States)

    Xu, Juntian; Gao, Kunshan

    2015-11-01

    Macroalgae distributed in intertidal zones experience a series of environmental changes, such as periodical desiccation associated with tidal cycles, increasing CO2 concentration and solar UVB (280-315 nm) irradiance in the context of climate change. We investigated how the economic red macroalga, Pyropia haitanensis, perform its photosynthesis under elevated atmospheric CO2 concentration and in the presence of solar UV radiation (280-400 nm) during emersion. Our results showed that the elevated CO2 (800 ppmv) significantly increased the photosynthetic carbon fixation rate of P. haitanensis by about 100% when the alga was dehydrated. Solar UV radiation had insignificant effects on the net photosynthesis without desiccation stress and under low levels of sunlight, but significantly inhibited it with increased levels of desiccation and sunlight intensity, to the highest extent at the highest levels of water loss and solar radiation. Presence of UV radiation and the elevated CO2 acted synergistically to cause higher inhibition of the photosynthetic carbon fixation, which exacerbated at higher levels of desiccation and sunlight. While P. haitanensis can benefit from increasing atmospheric CO2 concentration during emersion under low and moderate levels of solar radiation, combined effects of elevated CO2 and UV radiation acted synergistically to reduce its photosynthesis under high solar radiation levels during noon periods. © 2015 The American Society of Photobiology.

  11. Variations in constitutive and inducible UV-B tolerance; dissecting photosystem II protection in Arabidopsis thaliana accessions

    NARCIS (Netherlands)

    Jansen, M.A.K.; LeMartret, B.; Koornneef, M.

    2010-01-01

    The rise in ultraviolet-B (UV-B) (280315 nm) radiation levels, that is a consequence of stratospheric ozone layer depletion, has triggered extensive research on the effects of UV-B on plants. Plants raised under natural sunlight conditions are generally well protected from the potentially harmful

  12. UV-B Radiation Contributes to Amphibian Population Declines

    Science.gov (United States)

    Blaustein, Andrew

    2007-05-01

    UV-B (280-315 nm) radiation is the most significant biologically damaging radiation at the terrestrial surface. At the organismal level, UV-B radiation can slow growth rates, cause immune dysfunction and result in sublethal damage. UV-B radiation can lead to mutations and cell death. Over evolutionary time, UV radiation has been an important stressor on living organisms. Natural events, including impacts from comets and asteroids, volcanic activity, supernova explosions and solar flares, can cause large-scale ozone depletion with accompanying increases in UV radiation. However, these natural events are transient. Moreover, the amount of ozone damage due to natural events depends upon a number of variables, including the magnitude of the event. This is different from modern-day human-induced production of chlorofluorocarbons (CFCs) and other chemicals that deplete stratospheric ozone continuously, resulting in long-term increases in UV-B radiation at the surface of the earth. We will briefly review the effects of UV-B exposure in one group of aquatic organisms_amphibians. UV-B has been implicated as a possible factor contributing to global declines and range reductions in amphibian populations.

  13. Solar UV irradiances modulate effects of ocean acidification on the coccolithophorid Emiliania huxleyi.

    Science.gov (United States)

    Xu, Kai; Gao, Kunshan

    2015-01-01

    Emiliania huxleyi, the most abundant coccolithophorid in the oceans, is naturally exposed to solar UV radiation (UVR, 280-400 nm) in addition to photosynthetically active radiation (PAR). We investigated the physiological responses of E. huxleyi to the present day and elevated CO2 (390 vs 1000 μatm; with pH(NBS) 8.20 vs 7.86) under indoor constant PAR and fluctuating solar radiation with or without UVR. Enrichment of CO2 stimulated the production rate of particulate organic carbon (POC) under constant PAR, but led to unchanged POC production under incident fluctuating solar radiation. The production rates of particulate inorganic carbon (PIC) as well as PIC/POC ratios were reduced under the elevated CO2, ocean acidification (OA) condition, regardless of PAR levels, and the presence of UVR. However, moderate levels of UVR increased PIC production rates and PIC/POC ratios. OA treatment interacted with UVR to influence the alga's physiological performance, leading to reduced specific growth rate in the presence of UVA (315-400 nm) and decreased quantum yield, along with enhanced nonphotochemical quenching, with addition of UVB (280-315 nm). The results clearly indicate that UV radiation needs to be invoked as a key stressor when considering the impacts of ocean acidification on E. huxleyi. © 2014 The American Society of Photobiology.

  14. A database of 10 min average measurements of solar radiation and meteorological variables in Ostrava, Czech Republic

    Directory of Open Access Journals (Sweden)

    M. Opálková

    2018-04-01

    Full Text Available A database containing 10 min means of solar irradiance measured on a horizontal plane in several ultraviolet and visible bands from July 2014 to December 2016 at three stations in the area of the city of Ostrava (Czech Republic is presented. The database contains time series of 10 min average irradiances or photosynthetic photon flux densities measured in the following spectral bands: 280315nm (UVB; 315–380 nm (UVA; and 400–700 nm (photosynthetically active radiation, PAR; 510–700 nm; 600–700 nm; 610–680 nm; 690–780 nm; 400–1100 nm. A series of meteorological variables including relative air humidity and air temperature at surface is also provided at the same 10 min time step at all three stations, and precipitation is provided for two stations. Air pressure, wind speed, wind direction, and concentrations of air pollutants PM10, SO2, NOx, NO, NO2 were measured at the 1 h time step at the fourth station owned by the Public Health Institute of Ostrava. The details of the experimental sites and instruments used for the measurements are given. Special attention is given to the data quality, and the original approach to the data quality which was established is described in detail. About 130 000 records for each of the three stations are available in the database. This database offers a unique ensemble of variables having a high temporal resolution and it is a reliable source for radiation in relation to environment and vegetation in highly polluted areas of industrial cities in the of northern mid-latitudes. The database has been placed on the PANGAEA repository (https://doi.org/10.1594/PANGAEA.879722 and contains individual data files for each station.

  15. A database of 10 min average measurements of solar radiation and meteorological variables in Ostrava, Czech Republic

    Science.gov (United States)

    Opálková, Marie; Navrátil, Martin; Špunda, Vladimír; Blanc, Philippe; Wald, Lucien

    2018-04-01

    A database containing 10 min means of solar irradiance measured on a horizontal plane in several ultraviolet and visible bands from July 2014 to December 2016 at three stations in the area of the city of Ostrava (Czech Republic) is presented. The database contains time series of 10 min average irradiances or photosynthetic photon flux densities measured in the following spectral bands: 280-315 nm (UVB); 315-380 nm (UVA); and 400-700 nm (photosynthetically active radiation, PAR); 510-700 nm; 600-700 nm; 610-680 nm; 690-780 nm; 400-1100 nm. A series of meteorological variables including relative air humidity and air temperature at surface is also provided at the same 10 min time step at all three stations, and precipitation is provided for two stations. Air pressure, wind speed, wind direction, and concentrations of air pollutants PM10, SO2, NOx, NO, NO2 were measured at the 1 h time step at the fourth station owned by the Public Health Institute of Ostrava. The details of the experimental sites and instruments used for the measurements are given. Special attention is given to the data quality, and the original approach to the data quality which was established is described in detail. About 130 000 records for each of the three stations are available in the database. This database offers a unique ensemble of variables having a high temporal resolution and it is a reliable source for radiation in relation to environment and vegetation in highly polluted areas of industrial cities in the of northern mid-latitudes. The database has been placed on the PANGAEA repository (https://doi.org/10.1594/PANGAEA.879722" target="_blank">https://doi.org/10.1594/PANGAEA.879722) and contains individual data files for each station.

  16. Solar ultraviolet radiation and ozone depletion-driven climate change: effects on terrestrial ecosystems.

    Science.gov (United States)

    Bornman, J F; Barnes, P W; Robinson, S A; Ballaré, C L; Flint, S D; Caldwell, M M

    2015-01-01

    In this assessment we summarise advances in our knowledge of how UV-B radiation (280-315 nm), together with other climate change factors, influence terrestrial organisms and ecosystems. We identify key uncertainties and knowledge gaps that limit our ability to fully evaluate the interactive effects of ozone depletion and climate change on these systems. We also evaluate the biological consequences of the way in which stratospheric ozone depletion has contributed to climate change in the Southern Hemisphere. Since the last assessment, several new findings or insights have emerged or been strengthened. These include: (1) the increasing recognition that UV-B radiation has specific regulatory roles in plant growth and development that in turn can have beneficial consequences for plant productivity via effects on plant hardiness, enhanced plant resistance to herbivores and pathogens, and improved quality of agricultural products with subsequent implications for food security; (2) UV-B radiation together with UV-A (315-400 nm) and visible (400-700 nm) radiation are significant drivers of decomposition of plant litter in globally important arid and semi-arid ecosystems, such as grasslands and deserts. This occurs through the process of photodegradation, which has implications for nutrient cycling and carbon storage, although considerable uncertainty exists in quantifying its regional and global biogeochemical significance; (3) UV radiation can contribute to climate change via its stimulation of volatile organic compounds from plants, plant litter and soils, although the magnitude, rates and spatial patterns of these emissions remain highly uncertain at present. UV-induced release of carbon from plant litter and soils may also contribute to global warming; and (4) depletion of ozone in the Southern Hemisphere modifies climate directly via effects on seasonal weather patterns (precipitation and wind) and these in turn have been linked to changes in the growth of plants

  17. Measurement of the irradiation of generating lamps of radiation ultraviolet type A used in tan equipment Sportarredo model Ringo 1200

    International Nuclear Information System (INIS)

    Gama T, G.

    2010-09-01

    In the last years has been developed in the cosmetology market the application of ultraviolet radiation (UV) in known equipment s as cameras or tan beds to obtain a change in the pigmentation of the skin. In Mexico, this fashion has entered without the appropriate recommendations of prevention against the risks of the adverse effects from the disproportionate exhibition to such non ionizing energy form; which is electromagnetic radiation in the interval of 400 nm to 100 nm of wave longitude, classified in near UV-A of 400 nm to 315 nm, and distant: UV-B of 315 nm to 280 nm and UV-C of 280 nm to 100 nm. Therefore, they have not been included in the national normative the necessary regulations regarding the operation parameters of the tan cameras for the E irradiation levels. The level E is defined as the incident radiation power in a receiver surface to a specific localization and relative orientation to the radiant surface expressed in units of the International System, W/m 2 or MW/cm 2 . The objective of this work is to show the measurement results for the E of a camera that contains two emitters arrangements, a first to whole body that consist of 8 lamp pairs model B17L of 160 Watts, which will have a nominal E of 358 W/m 2 (35.8 MW/cm 2 ) for UV type A and 3.3 W/m 2 (0.33 MW/cm 2 ) for UV type B; one second to face of 8 lamps model KALFASUN 630, with an E of 568 W/m 2 (56.8 MW/cm 2 ) for UV type A and 2.97 W/m 2 (0.297 MW/cm 2 ) for UV type B. The E measurements are carried out for UV-A with the body and face lamp, respectively; with two instruments: photometer mark Sportarredo, model BF01, series E009, and radiometer mark Ets without specified model. Additional the treatment time is verified with the chronometer of the digital screen of the equipment comparing it with a digital meter with resolution of 0.001 s. Conclusion: the lamps do not fulfill the E nominal values reported by the manufacturer, being minors 3.2 to 1.75 times their nominal value for the body

  18. Does ultraviolet radiation affect the xanthophyll cycle in marine phytoplankton?

    NARCIS (Netherlands)

    van de Poll, W.H.; Buma, A.G.J.

    2009-01-01

    This Perspective summarizes the state of knowledge of the impact of ultraviolet radiation on the photoprotective xanthophyll cycle in marine phytoplankton. Excess photosynthetically active radiation (PAR; 400-700 nm) and ultraviolet radiation (UVR; 280-400 nm) affect various cellular processes and

  19. The study on highly expressed proteins as a function of an elevated ultraviolet radiation in the copepod, Tigriopus japonicus

    Science.gov (United States)

    Zubrzycki, Igor Z.; Lee, Seunghan; Lee, Kanghyun; Wiacek, Magdalena; Lee, Wonchoel

    2012-06-01

    The objective of the study was to analyze constantlyhighly expressed proteins as a function of elevated midultraviolet (UVB, 280-315 nm) radiation in Tigriopus japonicus sensu lato ( T. japonicus s.l). We also analyzed associations between kinetics of radiation avoidance, measured as a covered distance per time unit, and highly expressed proteins. The obtained results indicate an increase in T. japonicus s.l. mobility between the control (no radiation) and mild UV radiation levels (15 kJ·m-2). Two-dimensional gel electrophoresis combined with MALDI-MS-MS resulted in 2D protein map comprising of 686 protein spots, of which 19 were identified as highly expressed proteins across all experimental conditions. Obtained results indicate that calpain, vitellogenin, and collagenase are housekeeping protein that are expressed at a constant level independently of environmental changes and that adoption of a locomotive system for the avoidance of a UV source may be, at least partially, supported by hepatopancreas-driven metabolism.

  20. Daily, seasonal, and latitudinal variations in solar ultraviolet A and B radiation in relation to vitamin D production and risk for skin cancer.

    Science.gov (United States)

    Grigalavicius, Mantas; Moan, Johan; Dahlback, Arne; Juzeniene, Asta

    2016-01-01

    Solar ultraviolet (UV) radiation varies with latitude, time of day, and season. Both spectral UV composition and ambient UV dose lead to different health outcomes at different latitudes. Finding the optimal time for sun exposure, whereby the positive effects of UV exposure (vitamin D) are facilitated and the negative effects (skin cancer, photoimmunosuppression) avoided are the most important consideration in modern skin cancer prevention programs. This paper focuses on the latitude dependency of UVB, UVA, vitamin D production, and skin cancer risk in Caucasians. Biologically effective UVB (280-315 nm) and UVA (315-400 nm) doses were calculated using radiative transfer models with appropriate climatologic data for selected locations. Incidences of squamous cell carcinoma (SCC) and cutaneous melanoma (CM) were retrieved from cancer registries and published articles. Annual doses of UVA radiation decrease much less with increasing latitude than annual doses of UVB. Incidences of CM also decrease less steeply with increasing latitude than incidences of SCC. As SCC is caused mainly by UVB, these observations support the assumption that UVA plays an important role in the development of CM. The variations in UVA (relevant to CM) and UVB (relevant to vitamin D production) over 1 day differ: the UVB : UVA ratio is maximal at noon. The best way to obtain a given dose of vitamin D with minimal carcinogenic risk is through a non-burning exposure in the middle of the day, rather than in the afternoon or morning. © 2015 The International Society of Dermatology.

  1. The responses to supplementary of UV radiation of some temperate meadow species

    International Nuclear Information System (INIS)

    Cooley, N.M.

    2002-01-01

    Full text: The growth and development of various meadow species was monitored while growing under enhanced UV-radiation in the natural light environment. Growth responses to supplementary ultraviolet-B (UV-B+A) and ultraviolet-A (UV-A) were compared to the ambient daylight treatment for Bellis perennis, Cardamine pratensis, Cynosurus critatus and Ranunculus ficaria. When the response of ultraviolet A (UV-A) treated plants were compared with those of the UV-B+A, differences were found which varied according to the species and parameter investigated. To further understand the growth responses of the UV-A treatment and their relationship to the UV-B responses polychromatic action spectra in the natural environment was employed B perennis had an action maximum in the UV B (280-315 nm) while C cristatus demonstrates no action in the UV-B but action in the UV-A region (315-400 nm.). To enable further explanation of the effects of elevated UV radiation on the meadow plants Arabidopsis thaliana ecotypes and mutants were investigated. A thaliana ecotypes dry weight accumulation was found to respond differently to the UV treatments. UV B+A treatment was found to inhibit dry weight accumulation in most ecotypes. When UV B+A induced inhibition was expressed in terms of ambient growth rate for each ecotype a linear relationship could be derived. The higher the growth rate the more susceptible the ecotype was to UV-B+A inhibition. The pertinence of the UV-A treatment and UV protocol is discussed. It is suggested that UV responses could alter the diversity of the meadow equilibrium

  2. UV sensitivity of planktonic net community production in ocean surface waters

    OpenAIRE

    Regaudie de Gioux, Aurore; Agustí, Susana; Duarte, Carlos M.

    2014-01-01

    The net plankton community metabolism of oceanic surface waters is particularly important as it more directly affects the partial pressure of CO2 in surface waters and thus the air-sea fluxes of CO2. Plankton communities in surface waters are exposed to high irradiance that includes significant ultraviolet blue (UVB, 280-315 nm) radiation. UVB radiation affects both photosynthetic and respiration rates, increase plankton mortality rates, and other metabolic and chemical processes. Here we tes...

  3. Ultraviolet radiation in Finland

    Energy Technology Data Exchange (ETDEWEB)

    Taalas, P; Koskela, T; Damski, J; Supperi, A [Finnish Meteorological Inst., Helsinki (Finland). Section of Ozone and UV Research; Kyroe, E [Finnish Meteorological Inst., Sodankylae (Finland). Sodankylae Observatory

    1997-12-31

    Solar ultraviolet radiation is damaging for living organisms due to its high energy pro each photon. The UV radiation is often separated into three regions according to the wavelength: UVC (200-280 nm), UVB (280-320 nm) and UVA (320-400 nm). The most hazardous part, UVC is absorbed completely in the upper atmosphere by molecular oxygen. UVB radiation is absorbed by atmospheric ozone partly, and it is reaching Earth`s surface, as UVA radiation. Besides atmospheric ozone, very important factors in determining the intensity of UVB radiation globally are the solar zenith angle and cloudiness. It may be calculated from global ozone changes that the clear-sky UVB doses may have enhanced by 10-15 % during spring and 5-10 % during summer at the latitudes of Finland, following the decrease of total ozone between 1979-90. The Finnish ozone and UV monitoring activities have become a part of international activities, especially the EU Environment and Climate Programme`s research projects. The main national level effort has been the Finnish Academy`s climatic change programme, SILMU 1990-95. This presentation summarises the scientific results reached during the SILMU project

  4. Ultraviolet radiation in Finland

    Energy Technology Data Exchange (ETDEWEB)

    Taalas, P.; Koskela, T.; Damski, J.; Supperi, A. [Finnish Meteorological Inst., Helsinki (Finland). Section of Ozone and UV Research; Kyroe, E. [Finnish Meteorological Inst., Sodankylae (Finland). Sodankylae Observatory

    1996-12-31

    Solar ultraviolet radiation is damaging for living organisms due to its high energy pro each photon. The UV radiation is often separated into three regions according to the wavelength: UVC (200-280 nm), UVB (280-320 nm) and UVA (320-400 nm). The most hazardous part, UVC is absorbed completely in the upper atmosphere by molecular oxygen. UVB radiation is absorbed by atmospheric ozone partly, and it is reaching Earth`s surface, as UVA radiation. Besides atmospheric ozone, very important factors in determining the intensity of UVB radiation globally are the solar zenith angle and cloudiness. It may be calculated from global ozone changes that the clear-sky UVB doses may have enhanced by 10-15 % during spring and 5-10 % during summer at the latitudes of Finland, following the decrease of total ozone between 1979-90. The Finnish ozone and UV monitoring activities have become a part of international activities, especially the EU Environment and Climate Programme`s research projects. The main national level effort has been the Finnish Academy`s climatic change programme, SILMU 1990-95. This presentation summarises the scientific results reached during the SILMU project

  5. Physiological responses and toxin production of Microcystis aeruginosa in short-term exposure to solar UV radiation.

    Science.gov (United States)

    Hernando, Marcelo; Minaglia, Melina Celeste Crettaz; Malanga, Gabriela; Houghton, Christian; Andrinolo, Darío; Sedan, Daniela; Rosso, Lorena; Giannuzzi, Leda

    2018-01-17

    The aim of this study was to evaluate the effects of short-term (hours) exposure to solar UV radiation (UVR, 280-400 nm) on the physiology of Microcystis aeruginosa. Three solar radiation treatments were implemented: (i) PAR (PAR, 400-700 nm), (ii) TUVA (PAR + UVAR, 315-700 nm) and (iii) TUVR (PAR + UVAR + UVBR, 280-700 nm). Differential responses of antioxidant enzymes and the reactive oxygen species (ROS) production to UVR were observed. Antioxidant enzymes were more active at high UVR doses. However, different responses were observed depending on the exposure to UVAR or UVBR and the dose level. No effects were observed on the biomass, ROS production or increased activity of superoxide dismutase (SOD) and catalase (CAT) compared to the control when UVR + PAR doses were lower than 9875 kJ m -2 . For intermediate doses, UVR + PAR doses between 9875 and 10 275 kJ m -2 , oxidative stress increased while resistance was imparted through SOD and CAT in the cells exposed to UVAR. Despite the increased antioxidant activity, biomass decrease and photosynthesis inhibition were observed, but no effects were observed with added exposure to UVBR. At the highest doses (UVR + PAR higher than 10 275 kJ m -2 ), the solar UVR caused decreased photosynthesis and biomass with only activation of CAT by UVBR and SOD and CAT by UVAR. In addition, for such doses, a significant decrease of microcystins (MCs, measured as MC-LR equivalents) was observed as a consequence of UVAR. This study facilitates our understanding of the SOD and CAT protection according to UVAR and UVBR doses and cellular damage and reinforces the importance of UVR as an environmental stressor. In addition, our results support the hypothesized antioxidant function of MCs.

  6. Genetics perspective of UV rays and new alternatives for sun protection

    International Nuclear Information System (INIS)

    Vallejo, E.O.; Vargas, N.; Martínez, L.M.; Agudelo, C.A.; Ortiz, I.C.

    2013-01-01

    Ultraviolet (UV), has three different wavelengths: UVA (315-400 nm), UVB (280-315 nm) and UVC (100-280 nm), which impact in different ways on the skin of human beings, and may be responsible of skin aging, burns and cancers. Currently we have multiple sunscreen alternatives, ranging from conventional physical methods to complex molecular mechanisms and inducers of cell repair as Polypodium leucotomos. The purpose of this review is to show the implications of ultraviolet rays on human beings exposed to sunlight and the protection alternatives that are available and show what is to come in photo protection towards the future. (authors) [es

  7. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    ... oxyradicals invoked higher activity of antioxidant enzymes like superoxide dismutase and peroxidase under ambient UV, they also imposed limitation on the photosynthetic efficiency of PSII. Exclusion of UV components (UV-B 280315 nm; UV-A 315–400 nm) translated to enhanced photosynthesis, growth and biomass.

  8. Ultraviolet-B radiation influences the abundance and distribution of phylloplane fungi on pedunculate oak (Quercus robur)

    International Nuclear Information System (INIS)

    Newsham, K.K.; Low, M.N.R.; McLeod, A.R.; Greenslade, P.D.; Emmett, B.A.

    1997-01-01

    The effects of u.v.-B radiation (280-315 nm) on the fungi occurring on the lammas leaves of pedunculate oak (Quercus robur L.) were examined using saplings that were exposed at an outdoor facility to supplemental levels of u.v.-B radiation under treatment arrays of cellulose diacetate-filtered fluorescent lamps, which also produce u.v.-A radiation (315-400 nm). Saplings were also exposed to u.v.-A radiation alone under control arrays of polyester-filtered lamps, and to ambient levels of solar radiation under arrays of unenergized lamps. The u.v.-B treatment corresponded to a 30% elevation above the ambient level of erythemally-weighted u.v.-B radiation. The fungi were examined weekly over a 4-month-period in summer and autumn 1995 using two techniques, the spore fall and leaf impression methods, which differentiated between those fungi occurring on the upper (adaxial) and lower (abaxial) surfaces of the leaves. The abundances of Aureobasidium pullulans (De Bary) Arnaud and Sporobolomyces roseus Kluy. et van Niel, two leaf yeasts which had adaxial:abaxial ratios of < 1 under ambient levels of u.v.-B radiation, were negatively correlated with increasing ambient levels of u.v.-B radiation and were significantly reduced on adaxial leaf surfaces by supplemental levels of u.v.-B. There were few effects of supplemental u.v.-B radiation on the abundances of these yeasts on abaxial leaf surfaces. The abundances of the dematiaceous hyphomycetes, Cladosporium spp. and Epicoccum nigrum Link., species with adaxial:abaxial ratios of ⩾ 1 under ambient levels of u.v.-B radiation, were not correlated with ambient levels of u.v.-B radiation, nor were they usually affected on either leaf surface by supplemental u.v.-B radiation. Alternaria spp. and Microdochium nivale (Fr.) Samuels & Hallet showed consistent responses on adaxial leaf surfaces to u.v.-A radiation applied under control and treatment arrays. Our results suggest that current levels of shortwave radiation already

  9. The influence of UV irradiation on the photoreduction of iron in the Southern Ocean

    NARCIS (Netherlands)

    Rijkenberg, M J A; Fischer, AC; Kroon, JJ; Gerringa, LJA; Timmermans, KR; Wolterbeek, HT; de Baar, H J W

    2005-01-01

    An iron enrichment experiment, EisenEx, was performed in the Atlantic sector of the Southern Ocean during the Antarctic spring of 2000. Deck incubations of open ocean water were performed to investigate the influence of ultraviolet B (UVB: 280-315 nm) and ultraviolet A (UVA: 315-400 nm) on the

  10. Radiation Failures in Intel 14nm Microprocessors

    Science.gov (United States)

    Bossev, Dobrin P.; Duncan, Adam R.; Gadlage, Matthew J.; Roach, Austin H.; Kay, Matthew J.; Szabo, Carl; Berger, Tammy J.; York, Darin A.; Williams, Aaron; LaBel, K.; hide

    2016-01-01

    In this study the 14 nm Intel Broadwell 5th generation core series 5005U-i3 and 5200U-i5 was mounted on Dell Inspiron laptops, MSI Cubi and Gigabyte Brix barebones and tested with Windows 8 and CentOS7 at idle. Heavy-ion-induced hard- and catastrophic failures do not appear to be related to the Intel 14nm Tri-Gate FinFET process. They originate from a small (9 m 140 m) area on the 32nm planar PCH die (not the CPU) as initially speculated. The hard failures seem to be due to a SEE but the exact physical mechanism has yet to be identified. Some possibilities include latch-ups, charge ion trapping or implantation, ion channels, or a combination of those (in biased conditions). The mechanism of the catastrophic failures seems related to the presence of electric power (1.05V core voltage). The 1064 nm laser mimics ionization radiation and induces soft- and hard failures as a direct result of electron-hole pair production, not heat. The 14nm FinFET processes continue to look promising for space radiation environments.

  11. Enhancing carrier injection in the active region of a 280nm emission wavelength LED using graded hole and electron blocking layers

    KAUST Repository

    Janjua, Bilal; Ng, Tien Khee; Alyamani, Ahmed Y.; El-Desouki, Munir M.; Ooi, Boon S.

    2014-01-01

    A theoretical investigation of AlGaN UV-LED with band engineering of hole and electron blocking layers (HBL and EBL, respectively) was conducted with an aim to improve injection efficiency and reduce efficiency droop in the UV LEDs. The analysis is based on energy band diagrams, carrier distribution and recombination rates (Shockley-Reed-Hall, Auger, and radiative recombination rates) in the quantum well, under equilibrium and forward bias conditions. Electron blocking layer is based on AlaGa1-aN / Al b → cGa1-b → 1-cN / AldGa 1-dN, where a < d < b < c. A graded layer sandwiched between large bandgap AlGaN materials was found to be effective in simultaneously blocking electrons and providing polarization field enhanced carrier injection. The graded interlayer reduces polarization induced band bending and mitigates the related drawback of impediment of holes injection. Similarly on the n-side, the Alx → yGa1-x → 1-yN / AlzGa 1-zN (x < z < y) barrier acts as a hole blocking layer. The reduced carrier leakage and enhanced carrier density in the active region results in significant improvement in radiative recombination rate compared to a structure with the conventional rectangular EBL layers. The improvement in device performance comes from meticulously designing the hole and electron blocking layers to increase carrier injection efficiency. The quantum well based UV-LED was designed to emit at 280nm, which is an effective wavelength for water disinfection application.

  12. Enhancing carrier injection in the active region of a 280nm emission wavelength LED using graded hole and electron blocking layers

    KAUST Repository

    Janjua, Bilal

    2014-02-27

    A theoretical investigation of AlGaN UV-LED with band engineering of hole and electron blocking layers (HBL and EBL, respectively) was conducted with an aim to improve injection efficiency and reduce efficiency droop in the UV LEDs. The analysis is based on energy band diagrams, carrier distribution and recombination rates (Shockley-Reed-Hall, Auger, and radiative recombination rates) in the quantum well, under equilibrium and forward bias conditions. Electron blocking layer is based on AlaGa1-aN / Al b → cGa1-b → 1-cN / AldGa 1-dN, where a < d < b < c. A graded layer sandwiched between large bandgap AlGaN materials was found to be effective in simultaneously blocking electrons and providing polarization field enhanced carrier injection. The graded interlayer reduces polarization induced band bending and mitigates the related drawback of impediment of holes injection. Similarly on the n-side, the Alx → yGa1-x → 1-yN / AlzGa 1-zN (x < z < y) barrier acts as a hole blocking layer. The reduced carrier leakage and enhanced carrier density in the active region results in significant improvement in radiative recombination rate compared to a structure with the conventional rectangular EBL layers. The improvement in device performance comes from meticulously designing the hole and electron blocking layers to increase carrier injection efficiency. The quantum well based UV-LED was designed to emit at 280nm, which is an effective wavelength for water disinfection application.

  13. Ultraviolet-B and photosynthetically active radiation interactively affect yield and pattern of monoterpenes in leaves of peppermint (Mentha x piperita L.).

    Science.gov (United States)

    Behn, Helen; Albert, Andreas; Marx, Friedhelm; Noga, Georg; Ulbrich, Andreas

    2010-06-23

    Solar radiation is a key environmental signal in regulation of plant secondary metabolism. Since metabolic responses to light and ultraviolet (UV) radiation exposure are known to depend on the ratio of spectral ranges (e.g., UV-B/PAR), we examined effects of different UV-B radiation (280-315 nm) and photosynthetically active radiation (PAR, 400-700 nm) levels and ratios on yield and pattern of monoterpenoid essential oil of peppermint. Experiments were performed in exposure chambers, technically equipped for realistic simulation of natural climate and radiation. The experimental design comprised four irradiation regimes created by the combination of two PAR levels including or excluding UV-B radiation. During flowering, the highest essential oil yield was achieved at high PAR (1150 micromol m(-2) s(-1)) and approximate ambient UV-B radiation (0.6 W m(-2)). Regarding the monoterpene pattern, low PAR (550 micromol m(-2) s(-1)) and the absence of UV-B radiation led to reduced menthol and increased menthone contents and thereby to a substantial decrease in oil quality. Essential oil yield could not be correlated with density or diameter of peltate glandular trichomes, the epidermal structures specialized on biosynthesis, and the accumulation of monoterpenes. The present results lead to the conclusion that production of high quality oils (fulfilling the requirements of the Pharmacopoeia Europaea) requires high levels of natural sunlight. In protected cultivation, the use of UV-B transmitting covering materials is therefore highly recommended.

  14. UV-A enhanced growth and UV-B induced positive effects in the recovery of photochemical yield in Gracilaria lemaneiformis (Rhodophyta).

    Science.gov (United States)

    Xu, Juntian; Gao, Kunshan

    2010-09-02

    The effects of solar UV radiation (280-400 nm) on growth, quantum yield and pigmentation in Gracilaria lemaneiformis were investigated when the thalli were cultured under solar radiation with or without UV for a period of 15 days. Presence of UV-A (315-400 nm) enhanced the relative growth rate, while UV-B (218-315 nm) inhibited it. The positive effect of UV-A and negative effect of UV-B counteracted to result in an insignificant impact of UVR on growth. During the noon period, both UV-A and UV-B resulted in the decrease of maximum quantum yield (Fv/Fm), but UV-B aided in the recovery of the yield in the late afternoon, reflecting that UV-B might be used as a signal in photorepair processes. UV induced the accumulation of UV-absorbing compounds (UVAC) to defend against the harmful UVR. However, the accumulation of UVAC took a much longer time compared to that previously reported, which was probably due to the lower levels of solar radiation and water temperature in the early spring period. Unknown UV-absorbing compounds (UVAC), which peaked at 265 nm, probably the precursor of MAAs (UVAC(325)), accumulated under moderate levels of solar radiation and were transformed to MAAs under higher solar radiation. Copyright (c) 2010 Elsevier B.V. All rights reserved.

  15. The effect of ionizing radiation on intraocular lenses

    International Nuclear Information System (INIS)

    Ellerin, Bruce E.; Nisce, Lourdes Z.; Roberts, Calvin W.; Thornell, Cliff; Sabbas, Albert; Wang Huili; Li, P. Mark; Nori, Dattatreyudu

    2001-01-01

    Background: The native crystalline lens is the principal shield against ultraviolet radiation (UV), damage to the human retina. Every year in the United States, more than one million patients undergo removal of the natural lens in the course of cataract surgery (phakectomy), at which time an intraocular lens (IOL) is placed in the lens capsule. The IOL thenceforth serves as the principal barrier to ultraviolet radiation over the life of the implant, potentially for decades. The synthetic organic molecules of which IOLs are composed offer little UV protection unless ultraviolet-absorbing chromophores are incorporated into the lens material during manufacture. However, chromophores are alkenes potentially subject to radiolytic degradation. It is unknown whether ionizing radiation at clinical doses (e.g., to the brain or in the head-and-neck region) affects the UV-absorbing capacity of chromophore-bearing IOLs and consequently exposes the retina to potentially chronic UV damage. In addition, the polymers of which IOLs are composed are themselves subject to radiation damage, which theoretically might result in optical distortion in the visible light range. Objective: To determine whether megavoltage photon ionizing radiation alters the absorption spectra of ultraviolet-shielding polymethylmethacrylate (PMMA) and organopolysiloxane (silicone) intraocular lenses (IOLs) in the UV (280 nm ≤ λ < 400 nm), visible (400 nm ≤ λ ≤ 700 nm), and low-end near-infrared (700 nm < λ ≤ 830 nm) ranges. Design: Prospective, nonrandomized trial of dose-paired IOL cohorts. Methods: Fourteen IOLs, seven of PMMA (Chiron 6842B) and seven of silicone (IOLAB L141U), were paired and examined for absorption spectra in 1-nm intervals over the range λ = 280-830 nm on a Cary 400 deuterium and quartz halogen source-lamp UV/visible spectrophotometer before and after undergoing megavoltage ionizing irradiation to doses of 2, 5, 10, 20, 40, 60, and 100 Gray, respectively. Because of

  16. Comparison of the ablation ability of nucleus pulposus after 1,064 nm Nd:YAG laser and 980 nm diode laser radiation.

    Science.gov (United States)

    Yin, Jian; Han, Zhengfeng; Guo, Baofeng; Guo, Han; Zhang, Tongtong; Zeng, Yanjun; Ren, Longxi

    2015-07-01

    To compare the ablation ability of nucleus pulposus after 1,064 nm Nd:YAG laser and 980 nm diode laser radiation. Goat spine specimen (GSS) was radiated using Nd:YAG laser and 980 nm diode laser and then divided into five groups based on the final energy--200, 400, 600, 800 and 1,000 J groups. The ablation quality of nucleus pulposus after radiation was recorded. The ablation quality of GSS was greater at higher radiation energies in both lasers. When compared at the same energy level, the ablation quality of GSS was greater in 980 nm diode laser than in 1,064 nm Nd:YAG laser. Statistical significance was observed in 200 and 400 J groups (P diode laser showed better ablation ability than 1,064 nm Nd:YAG laser.

  17. UV-B radiation and photosynthetic irradiance acclimate eggplant for outdoor exposure

    International Nuclear Information System (INIS)

    Latimer, J.G.; Mitchell, G.A.

    1987-01-01

    Treatment of greenhouse-grown eggplant (Solanum melongena L. var. esculentum Nees. 'Burpee's Black Beauty') seedlings with supplemental photosynthetically active radiation from cool-white fluorescent lamps increased growth of plants subsequently transferred outdoors relative to growth of plants that received no supplemental radiation or were shaded to 45% of solar irradiation in the greenhouse before transfer outdoors. Eggplant seedlings transferred outdoors were placed under plastic tarps either to provide relative protection from solar ultraviolet-B (UV-B) radiation (280-315 nm) using Mylar film or to allow exposure to UV-B using cellulose acetate. Protection of seedlings from UV-B radiation resulted in greater leaf expansion than for UV-B-exposed seedlings, but no change in leaf or shoot dry weight occurred after 9 days of treatment. Specific leaf weight increased in response to UV-B exposure outdoors. Exposure of eggplant to UV-B radiation from fluorescent sunlamps in the greenhouse also decreased leaf expansion and leaf and shoot dry weight gain after 5 days of treatment. However, there were no differences in leaf or shoot dry weight relative to control plants after 12 days of UV-B treatment, indicating that UV-B treated plants had acclimated to the treatment and actually had caught up with non-UV-B-irradiated plants in terms of growth

  18. Elevated UV-B radiation incident on Quercus robur leaf canopies enhances decomposition of resulting leaf litter in soil

    International Nuclear Information System (INIS)

    Newsham, K.K.; Greenslade, P.D.; Kennedy, V.H.; McLeod, A.R.

    1999-01-01

    We examined whether the exposure of Quercus robur L. to elevated UV-B radiation (280315 nm) during growth would influence leaf decomposition rate through effects on litter quality. Saplings were exposed for eight months at an outdoor facility in the UK to a 30% elevation above the ambient level of erythemally weighted UV-B radiation under UV-B treatment arrays of fluorescent lamps filtered with cellulose diacetate, which transmitted both UV-B and UV-A (315–400 nm) radiation. Saplings were exposed to elevated UV-A alone under control arrays of lamps filtered with polyester and to ambient radiation under unenergised arrays of lamps. Abscised leaves from saplings were enclosed in 1 mm2 mesh nylon bags, placed in a Quercus–Fraxinus woodland and were sampled at 0.11, 0.53, 1.10 and 1.33 years for dry weight loss, chemical composition and saprotrophic fungal colonization. At abscission, litters from UV-A control arrays had ≈ 7.5% higher lignin/nitrogen ratios than those from UV-B treatment and ambient arrays (P < 0.06). Dry weight loss of leaves treated with elevated UV-B radiation during growth was 2.5% and 5% greater than that of leaves from UV-A control arrays at 0.53 and 1.33 years, respectively. Litter samples from UV-B treatment arrays lost more nitrogen and phosphorus than samples from ambient arrays and more carbon than samples from UV-A control arrays. The annual fractional weight loss of litter from UV-B treatment arrays was 8% and 6% greater than that of litter from UV-A control and ambient arrays, respectively. Regression analyses indicated that the increased decomposition rate of UV-B treated litters was associated with enhanced colonization of leaves by basidiomycete fungi, the most active members of the soil fungal community, and that the frequency of these fungi was negatively associated with the initial lignin/nitrogen ratio of leaves. (author)

  19. Multiple Roles for UV RESISTANCE LOCUS8 in Regulating Gene Expression and Metabolite Accumulation in Arabidopsis under Solar Ultraviolet Radiation1[W][OA

    Science.gov (United States)

    Morales, Luis O.; Brosché, Mikael; Vainonen, Julia; Jenkins, Gareth I.; Wargent, Jason J.; Sipari, Nina; Strid, Åke; Lindfors, Anders V.; Tegelberg, Riitta; Aphalo, Pedro J.

    2013-01-01

    Photomorphogenic responses triggered by low fluence rates of ultraviolet B radiation (UV-B; 280315 nm) are mediated by the UV-B photoreceptor UV RESISTANCE LOCUS8 (UVR8). Beyond our understanding of the molecular mechanisms of UV-B perception by UVR8, there is still limited information on how the UVR8 pathway functions under natural sunlight. Here, wild-type Arabidopsis (Arabidopsis thaliana) and the uvr8-2 mutant were used in an experiment outdoors where UV-A (315–400 nm) and UV-B irradiances were attenuated using plastic films. Gene expression, PYRIDOXINE BIOSYNTHESIS1 (PDX1) accumulation, and leaf metabolite signatures were analyzed. The results show that UVR8 is required for transcript accumulation of genes involved in UV protection, oxidative stress, hormone signal transduction, and defense against herbivores under solar UV. Under natural UV-A irradiance, UVR8 is likely to interact with UV-A/blue light signaling pathways to moderate UV-B-driven transcript and PDX1 accumulation. UVR8 both positively and negatively affects UV-A-regulated gene expression and metabolite accumulation but is required for the UV-B induction of phenolics. Moreover, UVR8-dependent UV-B acclimation during the early stages of plant development may enhance normal growth under long-term exposure to solar UV. PMID:23250626

  20. Measurement of the irradiation of generating lamps of radiation ultraviolet type A used in tan equipment Sportarredo model Ringo 1200; Medicion de la irradiancia de lamparas generadoras de radiacion ultravioleta tipo A usadas en equipo de bronceado Sportarredo Modelo Ringo 1200

    Energy Technology Data Exchange (ETDEWEB)

    Gama T, G., E-mail: cxxi@prodigy.net.m [Calidad XXI, Zacatecas 67-007, Col. Roma, 06700 Mexico D. F. (Mexico)

    2010-09-15

    In the last years has been developed in the cosmetology market the application of ultraviolet radiation (UV) in known equipment s as cameras or tan beds to obtain a change in the pigmentation of the skin. In Mexico, this fashion has entered without the appropriate recommendations of prevention against the risks of the adverse effects from the disproportionate exhibition to such non ionizing energy form; which is electromagnetic radiation in the interval of 400 nm to 100 nm of wave longitude, classified in near UV-A of 400 nm to 315 nm, and distant: UV-B of 315 nm to 280 nm and UV-C of 280 nm to 100 nm. Therefore, they have not been included in the national normative the necessary regulations regarding the operation parameters of the tan cameras for the E irradiation levels. The level E is defined as the incident radiation power in a receiver surface to a specific localization and relative orientation to the radiant surface expressed in units of the International System, W/m{sup 2} or MW/cm{sup 2}. The objective of this work is to show the measurement results for the E of a camera that contains two emitters arrangements, a first to whole body that consist of 8 lamp pairs model B17L of 160 Watts, which will have a nominal E of 358 W/m{sup 2} (35.8 MW/cm{sup 2}) for UV type A and 3.3 W/m{sup 2} (0.33 MW/cm{sup 2}) for UV type B; one second to face of 8 lamps model KALFASUN 630, with an E of 568 W/m{sup 2} (56.8 MW/cm{sup 2}) for UV type A and 2.97 W/m{sup 2} (0.297 MW/cm{sup 2}) for UV type B. The E measurements are carried out for UV-A with the body and face lamp, respectively; with two instruments: photometer mark Sportarredo, model BF01, series E009, and radiometer mark Ets without specified model. Additional the treatment time is verified with the chronometer of the digital screen of the equipment comparing it with a digital meter with resolution of 0.001 s. Conclusion: the lamps do not fulfill the E nominal values reported by the manufacturer, being minors 3.2 to

  1. Enhancement of root growth and nitrogen fixation in Trigonella by UV-exclusion from solar radiation.

    Science.gov (United States)

    Sharma, Sonika; Guruprasad, K N

    2012-12-01

    A field experiment was conducted to study the impact of solar UV on root growth and nitrogen fixation in Trigonella foenum-graecum. Plants were grown in iron mesh cages covered with polyester filters that could specifically cut off UV-B (280-315 nm) or UV-A + B (280-400 nm) part of the solar spectrum. The control plants were grown under a polythene filter transmissible to UV. Root biomass, number of nodules and nodule fresh weight were enhanced after exclusion of solar UV. Nitrogenase activity was significantly enhanced by 120% and 80% in the UV-B and UV-A + B excluded plants respectively. Along with nitrogenase there was concomitant increase in leghemoglobin and hemechrome content in the nodules after exclusion of solar UV. These components of sunlight limits nitrogen fixation and their elimination can enhance nitrogen fixation with agricultural advantages like reduction in the use of fertilizers. Copyright © 2012 Elsevier Masson SAS. All rights reserved.

  2. Mitotic effects of monochromatic ultraviolet radiation at 225, 265, and 280 nm on eleven stages of the cell cycle of the grasshopper neuroblast in culture. II. Changes in progression rate and cell sequence between the stage irradiated and nuclear membrane breakdown

    International Nuclear Information System (INIS)

    Carlson, J.G.

    1976-01-01

    Portions of embryos of the grasshopper, Chortophaga viridifasciata (DeGeer), were cultured in hanging drops under quartz cover slips. Immediately after exposure to 225, 265, or 280 nm radiation, microscope observations at 38 0 C were begun. The morphologically identified stage and the time after treatment of selected neuroblasts were recorded at short-time intervals until prometaphase was reached. Mitotic retardation induced by irradiation of prereplication stages (metaphase, anaphase, or early telophase) or S phase (middle or late telophase, interphase, or very early prophase) is greatest in postreplication stages (early, middle, and late prophase) and absent or minimal in stages morphologically identified as parts of S phase. Ultraviolet irradiation superimposes on the normal diversity of progression rates an additional variation factor, so that cells do not necessarily reach prometaphase in the order of their sequence at the time of treatment. This suggests the need for caution in ascribing particular radiosensitivities to substages of limited duration on the basis of the order in which they attain a subsequent stage

  3. Soybean resistance to stink bugs (Nezara viridula and Piezodorus guildinii) increases with exposure to solar UV-B radiation and correlates with isoflavonoid content in pods under field conditions.

    Science.gov (United States)

    Zavala, Jorge A; Mazza, Carlos A; Dillon, Francisco M; Chludil, Hugo D; Ballaré, Carlos L

    2015-05-01

    Solar UV-B radiation (280-315nm) has a significant influence on trophic relationships in natural and managed ecosystems, affecting plant-insect interactions. We explored the effects of ambient UV-B radiation on the levels of herbivory by stink bugs (Nezara viridula and Piezodorus guildinii) in field-grown soybean crops. The experiments included two levels of UV-B radiation (ambient and attenuated UV-B) and four soybean cultivars known to differ in their content of soluble leaf phenolics. Ambient UV-B radiation increased the accumulation of the isoflavonoids daidzin and genistin in the pods of all cultivars. Soybean crops grown under attenuated UV-B had higher numbers of unfilled pods and damaged seeds than crops grown under ambient UV-B radiation. Binary choice experiments with soybean branches demonstrated that stink bugs preferred branches of the attenuated UV-B treatment. We found a positive correlation between percentage of undamaged seeds and the contents of daidzin and genistin in pods. Our results suggest that constitutive and UV-B-induced isoflavonoids increase plant resistance to stink bugs under field conditions. © 2014 John Wiley & Sons Ltd.

  4. Comparative mutagenesis and interaction between near-ultraviolet (313- to 405-nm) and far-ultraviolet (254-nm) radiation in Escherichia coli strains with differing repair capabilities

    International Nuclear Information System (INIS)

    Turner, M.A.; Webb, R.B.

    1981-01-01

    Comparative mutagenesis and possible synergistic interaction between broad-spectrum (313- to 405-nm) near-ultraviolet (black light bulb [BLB]) radiation and 254-nm radiation were studied in Escherichia coli strains WP2 (wild type), WP2s (uvrA), WP10 (recA), WP6 (polA), WP6s (polA uvrA), WP100 (uvrA recA), and WP5 (lexA). With BLB radiation, strains WP2s and WP6s demonstrated a high level of mutagenesis, whereas strains WP2, WP5, WP6, WP10, and WP100 did not demonstrate significant mutagenesis. In contrast, 254-nm radiation was mutagenic in strains WP2, WP2s, WP6, and WP6s, but strains WP5, WP10, and WP100 were not significantly mutated. The absence of mutagenesis by BLB radiation in lexA and recA strains WP10, WP5, and WP100 suggests that lex + rec + repair may play a major role in mutagenesis by both BLB and 254-nm radiation. The hypothesis that BLB radiation selectively inhibits rec + lex + repair was tested by sequential BLB-254 nm radiation. With strain WP2, a fluence of 30 J/m 2 at 254 nm induced trp + revertants at a frequency of 15 x 10 -6 . However, when 10 5 J/m 2 or more BLB radiation preceded the 254-nm exposure, no trp + revertants could be detected. A similar inhibition of 254-nm mutagenesis was observed with strain WP6 (polA). However, strains WP2s (uvrA) and WP6s (polA uvrA) showed enhanced 254-nm mutagenesis when a prior exposure to BLB radiation was given

  5. Effect of ionizing radiation on aqueous solution of insulin. [Gamma radiation

    Energy Technology Data Exchange (ETDEWEB)

    Kopoldova, J [Ceskoslovenska Akademie Ved, Prague. Isotopova Laborator Biologickych Ustavu; Nobilis, M [Vyzkumny Ustav pro Farmacii a Biochemii, Prague (Czechoslovakia)

    1977-02-01

    A 3.1x10/sup -4/ M aqueous solution of insulin was irradiated with /sup 60/Co in oxygenated, oxygen-limited, and oxygen-free atmosphere. The irradiated solutions were separated on a Sephadex G-75 column, and the eluates were determined spectrophotometrically at 280 nm. The decrease in the original content of insulin and the formation of radiation aggregates of insulin in dependence on radiation doses were studied. The total amount and molecular weights of radiation aggregates of insulin increased with increasing radiation dose while their biological activity and content of cys/2 residues decreased.

  6. Temperature dependence of UV radiation effects in Arctic and temperate isolates of three red macrophytes

    NARCIS (Netherlands)

    van de Poll, W.H.; Eggert, A.; Buma, A.G.J.; Breeman, Arno

    The temperature dependence of UV effects was studied for Arctic and temperate isolates of the red macrophytes Palmaria palmata, Coccotylus truncatus and Phycodrys rubens. The effects of daily repeated artificial ultraviolet B and A radiation (UVBR: 280-320 nm, UVAR: 320-400 nm) treatments were

  7. Arctic, Antarctic, and temperate green algae Zygnema spp. under UV-B stress: vegetative cells perform better than pre-akinetes.

    Science.gov (United States)

    Holzinger, Andreas; Albert, Andreas; Aigner, Siegfried; Uhl, Jenny; Schmitt-Kopplin, Philippe; Trumhová, Kateřina; Pichrtová, Martina

    2018-02-22

    Species of Zygnema form macroscopically visible mats in polar and temperate terrestrial habitats, where they are exposed to environmental stresses. Three previously characterized isolates (Arctic Zygnema sp. B, Antarctic Zygnema sp. C, and temperate Zygnema sp. S) were tested for their tolerance to experimental UV radiation. Samples of young vegetative cells (1 month old) and pre-akinetes (6 months old) were exposed to photosynthetically active radiation (PAR, 400-700 nm, 400 μmol photons m -2  s -1 ) in combination with experimental UV-A (315-400 nm, 5.7 W m -2 , no UV-B), designated as PA, or UV-A (10.1 W m -2 ) + UV-B (280-315 nm, 1.0 W m -2 ), designated as PAB. The experimental period lasted for 74 h; the radiation period was 16 h PAR/UV-A per day, or with additional UV-B for 14 h per day. The effective quantum yield, generally lower in pre-akinetes, was mostly reduced during the UV treatment, and recovery was significantly higher in young vegetative cells vs. pre-akinetes during the experiment. Analysis of the deepoxidation state of the xanthophyll-cycle pigments revealed a statistically significant (p UV-absorbing phenolic compounds was significantly higher (p UV-B stress than pre-akinetes.

  8. Effects of ultraviolet-B radiation on phytoplankton - zooplankton interactions = [Effecten van ultraviolet-B straling op interacties tussen fytoplankton en zooplankton

    NARCIS (Netherlands)

    Lange, de H.J.

    1999-01-01

    The decrease in stratospheric ozone concentration has received wide attention because the ozone layer protects the earth from harmful ultraviolet-B radiation (UVB, 280-320 nm). UVB radiation is harmful for organisms, and therefore scientific research into how UVB radiation affects organisms

  9. The effect of ultraviolet radiation on water-logging resistance in ...

    African Journals Online (AJOL)

    PRECIOUS

    2009-12-01

    Dec 1, 2009 ... similar defense systems to reduce cellular damages and a phenomenon ... UV-B radiation (280 - 320 nm) was provided by UV-B Lamps. (Beijing Normal .... of the experiment, water-logging led to a decrease of. SOD activity ...

  10. Ultraviolet Radiations: Skin Defense-Damage Mechanism.

    Science.gov (United States)

    Mohania, Dheeraj; Chandel, Shikha; Kumar, Parveen; Verma, Vivek; Digvijay, Kumar; Tripathi, Deepika; Choudhury, Khushboo; Mitten, Sandeep Kumar; Shah, Dilip

    2017-01-01

    UV-radiations are the invisible part of light spectra having a wavelength between visible rays and X-rays. Based on wavelength, UV rays are subdivided into UV-A (320-400 nm), UV-B (280-320 nm) and UV-C (200-280 nm). Ultraviolet rays can have both harmful and beneficial effects. UV-C has the property of ionization thus acting as a strong mutagen, which can cause immune-mediated disease and cancer in adverse cases. Numbers of genetic factors have been identified in human involved in inducing skin cancer from UV-radiations. Certain heredity diseases have been found susceptible to UV-induced skin cancer. UV radiations activate the cutaneous immune system, which led to an inflammatory response by different mechanisms. The first line of defense mechanism against UV radiation is melanin (an epidermal pigment), and UV absorbing pigment of skin, which dissipate UV radiation as heat. Cell surface death receptor (e.g. Fas) of keratinocytes responds to UV-induced injury and elicits apoptosis to avoid malignant transformation. In addition to the formation of photo-dimers in the genome, UV also can induce mutation by generating ROS and nucleotides are highly susceptible to these free radical injuries. Melanocortin 1 receptor (MC1R) has been known to be implicated in different UV-induced damages such as pigmentation, adaptive tanning, and skin cancer. UV-B induces the formation of pre-vitamin D3 in the epidermal layer of skin. UV-induced tans act as a photoprotection by providing a sun protection factor (SPF) of 3-4 and epidermal hyperplasia. There is a need to prevent the harmful effects and harness the useful effects of UV radiations.

  11. An action spectrum for UV-B radiation and the rat lens.

    Science.gov (United States)

    Merriam, J C; Löfgren, S; Michael, R; Söderberg, P; Dillon, J; Zheng, L; Ayala, M

    2000-08-01

    To determine an action spectrum for UV-B radiation and the rat lens and to show the effect of the atmosphere and the cornea on the action spectrum. One eye of young female rats was exposed to 5-nm bandwidths of UV-B radiation (290, 295, 300, 305, 310, and 315 nm). Light scattering of exposed and nonexposed lenses was measured 1 week after irradiation. A quadratic polynomial was fit to the dose-response curve for each wave band. The dose at each wave band that produced a level of light scattering greater than 95% of the nonexposed lenses was defined as the maximum acceptable dose (MAD). Transmittance of the rat cornea was measured with a fiberoptic spectrophotometer. The times to be exposed to the MAD in Stockholm (59.3 degrees N) and La Palma (28 degrees N) were compared. Significant light scattering was detected after UV-B at 295, 300, 305, 310, and 315 nm. The lens was most sensitive to UV-B at 300 nm. Correcting for corneal transmittance showed that the rat lens is at least as sensitive to UV radiation at 295 nm as at 300 nm. The times to be exposed to the MAD at each wave band were greater in Stockholm than in La Palma, and in both locations the theoretical time to be exposed to the MAD was least at 305 nm. After correcting for corneal transmittance, the biological sensitivity of the rat lens to UV-B is at least as great at 295 nm as at 300 nm. After correcting for transmittance by the atmosphere, UV-B at 305 nm is the most likely wave band to injure the rat lens in both Stockholm and La Palma.

  12. Impacts of diurnal variation of ultraviolet-B and photosynthetically active radiation on phycobiliproteins of the hot-spring cyanobacterium Nostoc sp. strain HKAR-2.

    Science.gov (United States)

    Kannaujiya, Vinod K; Sinha, Rajeshwar P

    2017-01-01

    The effects of diurnal variation of photosynthetically active radiation (PAR; 400-700 nm) and ultraviolet-B (UV-B; 280-315 nm) radiation on phycobiliproteins (PBPs) and photosynthetic pigments (PP) have been studied in the hot-spring cyanobacterium Nostoc sp. strain HKAR-2. The variations in PBPs and PP were monitored by alternating light and dark under PAR, UV-B, and PAR + UV-B radiations over a period of 25 h. There was a decline in the amount of Chl a and PBPs during light periods of UV-B and PAR + UV-B and an increase during dark periods showing a circadian rhythm by destruction and resynthesis of pigment-protein complex. However, a marked induction in carotenoids was recorded during light periods of the same radiations. Moreover, the ratio of Chl a/PE and Chl a/PC was increased in dark periods showing the resynthesis of bleached Chl a. The wavelength shift in emission fluorescence of PBPs toward shorter wavelengths further indicated the bleaching and destruction of PBPs during light periods. Oxidative damage upon exposure to PAR, UV-B, and PAR + UV-B was alleviated by induction of antioxidative enzymes such as superoxide dismutase (SOD), catalase (CAT), and ascorbate peroxidase (APX). The studied cyanobacterium exhibits a significant increase in the activities of SOD, CAT, and APX upon exposure to UV-B and PAR + UV-B radiations. The results indicate that pigment-protein composition of Nostoc sp. stain HKAR-2 was significantly altered during diurnal variation of light/radiation, which might play an important role in optimization for their productivity in a particular cyanobacterium.

  13. Confirmation of Non-Impacted Status (TA16-280 Complex)

    Energy Technology Data Exchange (ETDEWEB)

    Ruedig, Elizabeth [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-12-07

    EPC-ES finds that the materials associated with TA16-280 complex (see Figure 1) are candidates for release to the public for recycle or as sanitary/commercial waste. This finding is consistent with the requirements of DOE Order 458.1 Radiation Protection of the Public and the Environment and LANL Policy 412 Environmental Radiation Protection.

  14. Enhancement of photosynthesis in Sorghum bicolor by ultraviolet radiation

    International Nuclear Information System (INIS)

    Johnson, G.A.; Day, T.A.

    2002-01-01

    We assessed the influence of ultraviolet radiation (UV) on net photosynthetic CO 2 assimilation rate (Pn) in Sorghum bicolor, with particular attention to examining whether UV can enhance Pn via direct absorption of UV and absorption of UV-induced blue fluorescence by photosynthetic pigments. A polychromatic UV response spectrum of leaves was constructed by measuring Pn under different UV supplements using filters that had sharp transmission cut-offs from 280 to 382 nm, against a background of non-saturating visible light. When the abaxial surface was irradiated, P n averaged 4.6% higher with the UV supplement that cut-off UV at 311 nm, compared to lower and higher UV wavelength supplements. This former supplement differed from higher wavelength supplements by primarily providing more UV between 320 and 350 nm. To assess the possibility of direct absorption of UV by photosynthetic pigments, we measured the absorbance of extracted chlorophylls. Chlorophyll a had absorbance peaks at 340 and 389 nm that were 49 and 72% of that at the sorét peak. Chlorophyll b had absorbance peaks at 315 and 346 nm that were both 35% of that at the sorét peak. Since the epidermis transmits some UV, the strong UV absorbance of chlorophyll implies a potential role for irradiance beyond the bounds of the conventionally defined photosynthetically active radiation waveband (400–700 nm). To assess the role of absorption of UV-induced blue fluorescence, we measured the UV-induced fluorescence excitation and emission spectra of leaves. Abaxial excitation peaked at 328 nm, while emission peaked at 446 nm. In this analysis, we used our abaxial fluorescence excitation spectrum and the UV photosynthetic inhibition spectrum of Caldwell et al. (1986) to weight the UV irradiance with each cut-off filter, thereby estimating the potential contribution of UV-induced blue fluorescence to photosynthesis and the inhibitory effects of UV irradiance on photosynthesis, respectively. With a non

  15. Study on discrimination of oral cancer from normal using blood plasma based on fluorescence steady and excited state at excitation wavelength 280 nm

    Science.gov (United States)

    Rekha, Pachaiappan; Aruna, Prakasa Rao; Ganesan, Singaravelu

    2016-03-01

    Many research works based on fluorescence spectroscopy have proven its potential in the diagnosis of various diseases using the spectral signatures of the native key fluorophores such as tryptophan, tyrosine, collagen, NADH, FAD and porphyrin. These fluorophores distribution, concentration and their conformation may be changed depending upon the pathological and metabolic conditions of cells and tissues. In this study, we have made an attempt to characterize the blood plasma of normal subject and oral cancer patients by native fluorescence spectroscopy at 280 nm excitation. Further, the fluorescence data were analyzed by employing the multivariate statistical method - linear discriminant analyses (LDA) using leaves one out cross validation method. The results illustrate the potential of fluorescence spectroscopy technique in the diagnosis of oral cancer using blood plasma.

  16. Induction of heat shock-like proteins in Vigna sinensis seedlings growing under ultraviolet-B (280-320 nm) enhanced radiation

    International Nuclear Information System (INIS)

    Nedunchezhian, N.; Annamalainathan, K.; Kulandaivelu, G.

    1992-01-01

    The effect of ultraviolet-B (UV-B) enhanced fluorescent radiation on protein profile and protein synthesis has been investigated in Vigna sinensis L. cv. Walp seedlings growing at various temperatures. In seedlings growing at 30°C, UV-B radiation decreased the level of several proteins as seen in Coomassie brilliant blue stained gel. However, fluorography of the same gel indicates induction of three sets of proteins in the range of 70. 53 and 16 k Da. Such induction under UV-B enhanced radiation resembled that found after heat shock treatments. In seedlings at 10 and 20°C, induction of such proteins varied both qualitatively and quantitatively. At 40°C. UV-B enhanced radiation caused a cumulative effect with temperature. Strong induction of specific proteins by UV-B radiation in seedlings growing under normal temperature indicates a possible protective role

  17. Radiation-induced transient attenuation of optical fibers at 800 and 1300 nm

    International Nuclear Information System (INIS)

    Looney, L.D.; Lyons, P.B.

    1987-01-01

    Radiation-induced absorption in optical fibers has been a subject of considerable interest throughout the world. As availability and applications of fibers have evolved from ''first window'' systems operating near 850 nm to ''second window'' systems near 1300 nm, interest in wavelength dependence of radiation effects in optical fibers has similarly evolved. The present work summarizes second-window, radiation-induced transient absorption measurements in optical fibers for times shorter than 5 μs. Comparisons to first window data for these fibers are also presented. Only high purity silica fibers with low-OH concentrations were used in the present study to avoid the large OH absorption band in this region. This paper also collects first window data on several high-OH optical fibers

  18. Study of the anticorrelations between ozone and UV-B radiation using linear and exponential fits in Southern Brazil

    Science.gov (United States)

    Guarnieri, R.; Padilha, L.; Guarnieri, F.; Echer, E.; Makita, K.; Pinheiro, D.; Schuch, A.; Boeira, L.; Schuch, N.

    Ultraviolet radiation type B (UV-B 280-315nm) is well known by its damage to life on Earth, including the possibility of causing skin cancer in humans. However, the atmo- spheric ozone has absorption bands in this spectral radiation, reducing its incidence on Earth's surface. Therefore, the ozone amount is one of the parameters, besides clouds, aerosols, solar zenith angles, altitude, albedo, that determine the UV-B radia- tion intensity reaching the Earth's surface. The total ozone column, in Dobson Units, determined by TOMS spectrometer on board of a NASA satellite, and UV-B radiation measurements obtained by a UV-B radiometer model MS-210W (Eko Instruments) were correlated. The measurements were obtained at the Observatório Espacial do Sul - Instituto Nacional de Pesquisas Espaciais (OES/CRSPE/INPE-MCT) coordinates: Lat. 29.44oS, Long. 53.82oW. The correlations were made using UV-B measurements in fixed solar zenith angles and only days with clear sky were selected in a period from July 1999 to December 2001. Moreover, the mathematic behavior of correlation in dif- ferent angles was observed, and correlation coefficients were determined by linear and first order exponential fits. In both fits, high correlation coefficients values were ob- tained, and the difference between linear and exponential fit can be considered small.

  19. Use of an improved radiation amplification factor to estimate the effect of total ozone changes on action spectrum weighted irradiances and an instrument response function

    Science.gov (United States)

    Herman, Jay R.

    2010-12-01

    Multiple scattering radiative transfer results are used to calculate action spectrum weighted irradiances and fractional irradiance changes in terms of a power law in ozone Ω, U(Ω/200)-RAF, where the new radiation amplification factor (RAF) is just a function of solar zenith angle. Including Rayleigh scattering caused small differences in the estimated 30 year changes in action spectrum-weighted irradiances compared to estimates that neglect multiple scattering. The radiative transfer results are applied to several action spectra and to an instrument response function corresponding to the Solar Light 501 meter. The effect of changing ozone on two plant damage action spectra are shown for plants with high sensitivity to UVB (280-315 nm) and those with lower sensitivity, showing that the probability for plant damage for the latter has increased since 1979, especially at middle to high latitudes in the Southern Hemisphere. Similarly, there has been an increase in rates of erythemal skin damage and pre-vitamin D3 production corresponding to measured ozone decreases. An example conversion function is derived to obtain erythemal irradiances and the UV index from measurements with the Solar Light 501 instrument response function. An analytic expressions is given to convert changes in erythemal irradiances to changes in CIE vitamin-D action spectrum weighted irradiances.

  20. Ultraviolet-B radiation effects on leaf fluorescence characteristics in cultivars of soybean

    International Nuclear Information System (INIS)

    Miles, D.

    1993-01-01

    Ultraviolet-B (UV-B; 280–320 nm)–emitting lamps unavoidably emit ultraviolet-A (UV-A; 320–400 nm) and ultraviolet-C (UV-C; <280 nm) radiation. Short-wavelength–blocking filters are generally used to limit the wave bands of UV under investigation. The widespread use of such filters means that all exposures to UV-B radiation will have a significant UV-A component. Therefore, the physiological effects unique to UV-B exposure are difficult to clearly isolate. This study presents a method to remove the UV-A and UV-C “contamination” using a liquid potassium chromate (K 2 CrO 4 ) filter, thus allowing more direct assessment of the effects of UV-B exposure. Cultures of the green marine alga Dunaliella tertiolecta were grown in the absence of UV radiation. Sunlamps supplied the UV radiation for a 24 h exposure (solar radiation was not used in this study). The UV radiation was filtered either by the standard method (i.e. cellulose acetate (CA) with polyester = Mylar controls) or by a liquid filter of potassium chromate. Photosynthetic responses were compared. Major decreases in the ratio of variable to maximal fluorescence in dark-adapted cells and photosynthetic capacity were observed in CA-filtered cultures, whereas no change was observed in cells exposed to the same UV-B flux with the UV-A removed by K 2 CrO 4 . The use of a CA filter with a Mylar control does not link results unequivocally to UV-B radiation. Such results should be interpreted with caution. (author)

  1. Study on the specificity of yeast cell damage by high-intensity UV radiation (266nm)

    International Nuclear Information System (INIS)

    Burchuladze, T.G.; Frajkin, G.Ya.; Rubin, L.B.

    1981-01-01

    Peculiarities of photoreactivation and photoprotection of the Candida guilliermondii and Candida utilis yeast cells, irradiated with far and near ultraviolet radiation, are considered. New results on the study of the dependence of the cells inactivation degree on the intensity of ultraviolet radiation are presented. The impulse rate density at 266 nm reached 10 10 Ix m -2 xs -1 at the impulse duration of 10 -8 s. Survival curves of the yeast cells during their irradiation with ultraviolet radiation of 266 nm and 254 nm are given. It is shown that with the increase of the irradiation intensity of 266 nm the rates and final levels of photoreactivation decrease. Under the effect of ultraviolet irradiation of high intensity contribution of pyrimidine dimers to the cell inactivation decreases [ru

  2. Association of dopamine D(3) receptors with actin-binding protein 280 (ABP-280).

    Science.gov (United States)

    Li, Ming; Li, Chuanyu; Weingarten, Paul; Bunzow, James R; Grandy, David K; Zhou, Qun Yong

    2002-03-01

    Proteins that bind to G protein-coupled receptors have been identified as regulators of receptor localization and signaling. In our previous studies, a cytoskeletal protein, actin-binding protein 280 (ABP-280), was found to associate with the third cytoplasmic loop of dopamine D(2) receptors. In this study, we demonstrate that ABP-280 also interacts with dopamine D(3) receptors, but not with D(4) receptors. Similar to the dopamine D(2) receptor, the D(3)/ABP-280 association is of signaling importance. In human melanoma M2 cells lacking ABP-280, D(3) receptors were unable to inhibit forskolin-stimulated cyclic AMP (cAMP) production significantly. D(4) receptors, however, exhibited a similar degree of inhibition of forskolin-stimulated cAMP production in ABP-280-deficient M2 cells and ABP-280-replent M2 subclones (A7 cells). Further experiments revealed that the D(3)/ABP-280 interaction was critically dependent upon a 36 amino acid carboxyl domain of the D(3) receptor third loop, which is conserved in the D(2) receptor but not in the D(4) receptor. Our results demonstrate a subtype-specific regulation of dopamine D(2)-family receptor signaling by the cytoskeletal protein ABP-280.

  3. Effects of ultraviolet radiation on photosynthetic performance and N2 fixation in Trichodesmium erythraeum IMS 101

    Science.gov (United States)

    Cai, Xiaoni; Hutchins, David A.; Fu, Feixue; Gao, Kunshan

    2017-10-01

    Biological effects of ultraviolet radiation (UVR; 280-400 nm) on marine primary producers are of general concern, as oceanic carbon fixers that contribute to the marine biological CO2 pump are being exposed to increasing UV irradiance due to global change and ozone depletion. We investigated the effects of UV-B (280-320 nm) and UV-A (320-400 nm) on the biogeochemically critical filamentous marine N2-fixing cyanobacterium Trichodesmium (strain IMS101) using a solar simulator as well as under natural solar radiation. Short exposure to UV-B, UV-A, or integrated total UVR significantly reduced the effective quantum yield of photosystem II (PSII) and photosynthetic carbon and N2 fixation rates. Cells acclimated to low light were more sensitive to UV exposure compared to high-light-grown ones, which had more UV-absorbing compounds, most likely mycosporine-like amino acids (MAAs). After acclimation under natural sunlight, the specific growth rate was lower (by up to 44 %), MAA content was higher, and average trichome length was shorter (by up to 22 %) in the full spectrum of solar radiation with UVR, than under a photosynthetically active radiation (PAR) alone treatment (400-700 nm). These results suggest that prior shipboard experiments in UV-opaque containers may have substantially overestimated in situ nitrogen fixation rates by Trichodesmium, and that natural and anthropogenic elevation of UV radiation intensity could significantly inhibit this vital source of new nitrogen to the current and future oligotrophic oceans.

  4. Effects of reducing the ambient UV-B radiation in the high Arctic on Salix arctica and Vaccinium uliginosum

    DEFF Research Database (Denmark)

    Albert, K.R.; Ro-Poulsen, H.; Mikkelsen, Teis Nørgaard

    2005-01-01

    , transmitting λ > 400 nm) were used to reduce UV-B radiation and UV-B+A respectively. A UV transparent film (Teflon, transmitting λ > 280 nm) and no film were used as controls. Field measurements showed that the plants under Teflon, Mylar and Lexan received app. 91%, 39% and 17% of the ambient UV-B irradiance...

  5. UV radiation induced stress does not affect DMSP synthesis in the marine prymnesiophyte Emiliania huxleyi

    NARCIS (Netherlands)

    van Rijssel, M; Buma, A.G.J.

    2002-01-01

    A possible coupling between UV radiation (UVR; 280 to 400 nm) induced stress and the production of dimethylsulfoniopropionate (DMSP), the precursor of the climate-regulating gas dimethylsulfide (DMS), was investigated in the marine prymnesiophyte Emiliania huxleyi. To this end, axenic cultures of E.

  6. On the interaction of UV-B radiation (280-315 mm) with water stress in crop plants

    International Nuclear Information System (INIS)

    Balakumar, T.; Vincent, V.H.B.; Paliwal, K.

    1993-01-01

    Cowpea (Vigna unguiculata L. Walp.) seedlings (3-day-old) were subjected to 4 kinds of experimental treatments: (1) control without exposure to any stress (-D-UV), (2) moderate water stress with no UV-B irradiation (+D-UV), (3) no water stress but exposure to UV-B radiation (-D+UV), and (4) moderate water stress and exposure to UV-B (+D+UV). UV-B and drought stress in the combined form elicited beneficial effects on the morphological and growth characteristics, and a few additive inhibitory effects in some functional processes. An increase in the specific leaf weight (SLW) was observed in the combination of stresses, which could be a defence mechanism against UV-B. The combination of stresses promoted the synthesis of anthocyanins and phenolic compounds. The responses of plants to the combination of stresses indicate that during simultaneous exposure of plants to multiple stresses, one form of stress could minimize the damage by the other. The enhancement of superoxide dismutase (SOD) and catalase activities appear to serve as acclimation mechanisms to scavenge the toxic, free radicals of oxygen produced under stress conditions. However, the inhibition in nitrate metabolism was greater in the combined stresses than in either of the stresses imposed separately. The results of this study illustrate that the interaction of stresses during simultaneous multiple stress conditions brings out certain beneficial effects. (author)

  7. Solar radiation measurements at the network of six sites in the UK, January - December 2001

    Energy Technology Data Exchange (ETDEWEB)

    Driscoll, C.M.H.; Campbell, J.I.; Pearson, A.J.; Grainger, K.J.L.; Dean, S.F.; Clark, I.E

    2002-04-01

    A summary of the results from January to December 2001 of a survey of solar radiation levels at the UK network of six solar radiation measurement sites is presented. The network consists of three NRPB sites at Chilton, Leeds and (monitoring since 1988) and three Meteorological Office stations at Camborne, Kinloss and Lerwick (monitoring since 1993). Visible (400-770 nm), ultraviolet UVA radiation (320-400 nm) and erythemally weighted ultraviolet radiation UVR{sub eff} (280-400 nm) have been measured simultaneously using a three detector measurement system. Results are compared with calculated irradiances of ultraviolet radiation and published illuminance data, and with data for the measurement period from 1988 to 2000. Yearly reports have been produced for selected sites, giving the daily solar index (which is a measure of the sunburn potential for sensitive skin types) throughout the year. (author)

  8. Solar radiation measurements at the network of six sites in the UK, January - December 2001

    International Nuclear Information System (INIS)

    Driscoll, C.M.H.; Campbell, J.I.; Pearson, A.J.; Grainger, K.J.L.; Dean, S.F.; Clark, I.E.

    2002-01-01

    A summary of the results from January to December 2001 of a survey of solar radiation levels at the UK network of six solar radiation measurement sites is presented. The network consists of three NRPB sites at Chilton, Leeds and (monitoring since 1988) and three Meteorological Office stations at Camborne, Kinloss and Lerwick (monitoring since 1993). Visible (400-770 nm), ultraviolet UVA radiation (320-400 nm) and erythemally weighted ultraviolet radiation UVR eff (280-400 nm) have been measured simultaneously using a three detector measurement system. Results are compared with calculated irradiances of ultraviolet radiation and published illuminance data, and with data for the measurement period from 1988 to 2000. Yearly reports have been produced for selected sites, giving the daily solar index (which is a measure of the sunburn potential for sensitive skin types) throughout the year. (author)

  9. Near ultraviolet radiation (280-400 nm): Direct and indirect effects on microbial pathogens

    International Nuclear Information System (INIS)

    Asthana, A.

    1993-01-01

    Responses of pigmented pathogenic fungi and E. coli strains differing in DNA repair and catalase proficiency to direct and indirect effects of ultraviolet radiation were evaluated. Pigments in the four fungal pathogens of Citrus differed in their ability to protect against direct UV and damage by UV-A -mediated phototoxins of both host and non-host origin. UV-A and UV-B did not inactivate the fungal species. Differential protection in wild type strains of the two Fusarium spp. and in the wild type strains of the two Penicilium spp. against UV-C was observed. Wild type and mutants with altered coloration in Penicilium spp. protected to varying extent against both α-T and 8-MOP in the presence of UV-A. UV-B irradiation of E. coli resulted in inactivation of strains deficient in DNA excision repair. Plasmid DNA damaged in vitro by UV-B from lamp systems as well as by sunlight, and transformed in vivo into bacterial cells lacking specific nucleases showed reduced transformation in DNA excision repair strains. UV-B enriched wavelengths isolated from a solar simulator affected plasmid DNA in a similar manner as UV-B from lamp systems. Sunlight, however affected the membrane of whole cells. Concentration of foliar furanocoumarins of Citrus jambhiri decreased with UV-B irradiation. Phototoxicity to Fusarium spp. was accounted for, in part, by furanocoumarins, psoralen and bergapten (5-MOP) and others. Pure psoralen and 5-MOP affected both Fusarium spp. similarly and carotenoids protected only partially in the wild type strains. Citrus targetted the cell membrane in Fusarium spp.l and in E. coli strains; carotenoids in both of which protected against such damage. Loss in structural integrity of plasmid DNA when treated with citral and UV-A correlated with loss in transforming activity. Biological damage to membrane and DNA was due to the production of hydrogen peroxide. Fruit-rot pathogens Penicilium spp. were not affected by either furanocoumarins or citrals

  10. Ecological responses to UV radiation: interactions between the biological effects of UV on plants and on associated organisms.

    Science.gov (United States)

    Paul, Nigel D; Moore, Jason P; McPherson, Martin; Lambourne, Cathryn; Croft, Patricia; Heaton, Joanna C; Wargent, Jason J

    2012-08-01

    Solar ultraviolet (UV)-B radiation (280-315 nm) has a wide range of effects on terrestrial ecosystems, yet our understanding of how UV-B influences the complex interactions of plants with pest, pathogen and related microorganisms remains limited. Here, we report the results of a series of experiments in Lactuca sativa which aimed to characterize not only key plant responses to UV radiation in a field environment but also consequential effects for plant interactions with a sap-feeding insect, two model plant pathogens and phylloplane microorganism populations. Three spectrally modifying filters with contrasting UV transmissions were used to filter ambient sunlight, and when compared with our UV-inclusive filter, L. sativa plants grown in a zero UV-B environment showed significantly increased shoot fresh weight, reduced foliar pigment concentrations and suppressed population growth of green peach aphid (Myzus persicae). Plants grown under a filter which allowed partial transmission of UV-A radiation and negligible UV-B transmission showed increased density of leaf surface phylloplane microbes compared with the UV-inclusive treatment. Effects of UV treatment on the severity of two plant pathogens, Bremia lactucae and Botrytis cinerea, were complex as both the UV-inclusive and zero UV-B filters reduced the severity of pathogen persistence. These results are discussed with reference to known spectral responses of plants, insects and microorganisms, and contrasted with established fundamental responses of plants and other organisms to solar UV radiation, with particular emphasis on the need for future integration between different experimental approaches when investigating the effects of solar UV radiation. Copyright © Physiologia Plantarum 2011.

  11. Effects of ultraviolet radiation on photosynthetic performance and N2 fixation in Trichodesmium erythraeum IMS 101

    Directory of Open Access Journals (Sweden)

    X. Cai

    2017-10-01

    Full Text Available Biological effects of ultraviolet radiation (UVR; 280–400 nm on marine primary producers are of general concern, as oceanic carbon fixers that contribute to the marine biological CO2 pump are being exposed to increasing UV irradiance due to global change and ozone depletion. We investigated the effects of UV-B (280–320 nm and UV-A (320–400 nm on the biogeochemically critical filamentous marine N2-fixing cyanobacterium Trichodesmium (strain IMS101 using a solar simulator as well as under natural solar radiation. Short exposure to UV-B, UV-A, or integrated total UVR significantly reduced the effective quantum yield of photosystem II (PSII and photosynthetic carbon and N2 fixation rates. Cells acclimated to low light were more sensitive to UV exposure compared to high-light-grown ones, which had more UV-absorbing compounds, most likely mycosporine-like amino acids (MAAs. After acclimation under natural sunlight, the specific growth rate was lower (by up to 44 %, MAA content was higher, and average trichome length was shorter (by up to 22 % in the full spectrum of solar radiation with UVR, than under a photosynthetically active radiation (PAR alone treatment (400–700 nm. These results suggest that prior shipboard experiments in UV-opaque containers may have substantially overestimated in situ nitrogen fixation rates by Trichodesmium, and that natural and anthropogenic elevation of UV radiation intensity could significantly inhibit this vital source of new nitrogen to the current and future oligotrophic oceans.

  12. Enhanced escape rate for Hg 254 nm resonance radiation in fluorescent lamps

    International Nuclear Information System (INIS)

    Lawler, James E; Raizen, Mark G

    2013-01-01

    The potential of the low-cost MAGIS isotopic separation method to improve fluorescent lamp efficacy is explored using resonance radiation transport simulations. New Hg isotopic mixes are discovered that yield escape rates for 254 nm Hg I resonance radiation equal to 117% to 122% of the rate for a natural isotopic mix under the same lamp conditions. (paper)

  13. Antiradiation UV Vaccine: UV Radiation, Biological effects, lesions and medical management - immune-therapy and immune-protection.

    Science.gov (United States)

    Popov, Dmitri; Jones, Jeffrey; Maliev, Slava

    Key Words: Ultraviolet radiation,Standard Erythema Dose(SED), Minimal Erythema Dose(MED), Sun Burns, Solar Dermatitis, Sun Burned Disease, DNA Damage,Cell Damage, Antiradiation UV Vaccine, Immune-Prophylaxis of Sun Burned Diseases, Immune-Prophylaxis of Sun Burns, Immune-Therapy of Sun-Burned Disease and Sun Burns,Basal Cell Carcinoma (BCC), Squamous Cell Carcinoma (SCC), Toxic Epidermal Necrolysis(TEN). Introduction: High doses of UV generated by solar source and artificial sources create an exposure of mammals and other species which can lead to ultraviolet(UV)radiation- associated disease (including erythema, epilation, keratitis, etc.). UV radiation belongs to the non-ionizing part of the electromagnetic spectrum and ranges between 100 nm and 400 nm with 100 nm having been chosen arbitrarily as the boundary between non-ionizing and ionizing radiation, however EMR is a spectrum and UV can produce molecular ionization. UV radiation is conventionally categorized into 3 areas: UV-A (>315-400 nm),UV-B (>280-315 nm)and UV-C (>100-280 nm) [IARC,Working Group Reports,2005] An important consequence of stratospheric ozone depletion is the increased transmission of solar ultraviolet (UV)radiation to the Earth's lower atmosphere and surface. Stratospheric ozone levels have been falling, in certain areas, for the past several decades, so current surface ultraviolet-B (UV-B) radiation levels are thought to be close to their modern day maximum. [S.Madronich et al.1998] Overexposure of ultraviolet radiation a major cause of skin cancer including basal cell carcinoma (BCC), squamous cell carcinoma (SCC) { collectively referred to as “non-melanoma" skin cancer (NMSC) and melanoma as well, with skin cancers being the most common cancer in North America. [Armstrong et al. 1993, Gallagher et al. 2005] Methods and Experimental Design: Our experiments and testing of a novel UV “Antiradiation Vaccine” have employed a wide variety of laboratory animals which include : Chinchilla

  14. Efecto de la radiación ultravioleta B en la producción de polifenoles en la microalga marina Chlorella sp. Effect of ultraviolet B radiation on the production of polyphenols in the marine microalga Chlorella sp.

    Directory of Open Access Journals (Sweden)

    Jaime Copia

    2012-03-01

    Full Text Available Las algas marinas son una fuente importante de compuestos antioxidantes (fenoles y polifenoles, generados como mecanismos de defensa frente a factores de estrés (radiación UV, temperatura, herbívora. El objetivo de este trabajo es evaluar la estrategia de adaptación al efecto de la radiación ultravioleta B (RUV-B, 280-315 nm en la microalga marina Chlorella sp. mediante la producción de polifenoles y capacidad antioxidante total. Se expusieron cultivos de Chlorella sp. fueron expuestos a radiación UV-B (470 μW cm-2 por periodo de tiempos ascendentes. Se evaluó la capacidad antioxidante total DPPH, polifenoles totales, clorofila-a y b así como la densidad celular en cultivos expuestos y no expuestos. Los resultados indicaron que la RUV-B genera una disminución de la densidad celular en los cultivos irradiados por primera vez (1ª etapa, existiendo un aumento significativo (P Marine algae are an important source of antioxidant compounds (phenols and polyphenols, generated as defense mechanisms against stress factors (UV radiation, temperature, herbivory. The aim of this study was to evaluate the strategy of adaptation to the effect of ultraviolet B radiation (UV-B, 280-315 nm in the marine microalga Chlorella sp. through, the production of polyphenols and total antioxidant capacity. Chlorella sp. cultures were exposed to UV-B radiation (470 μW cm-2 over increasing time periods. We evaluated the total antioxidant capacity DPPH, total polyphenols, chlorophyll-a and b, and cell densities in exposed and unexposed cultures. The results indicated that UV-B caused a decrease in cell density in cultures irradiated for the first time (1st stage, with a significant increment (P < 0.05, lower than the control in the 2nd and 3rd stages only through the 4th stage (day 7, corresponding to a dose of 16,920 J m-2. The production of total phenols increased significantly (P < 0.05 for the IVth extract with respect to the control, confirming that the

  15. Beneficial effects of solar UV-B radiation on soybean yield mediated by reduced insect herbivory under field conditions.

    Science.gov (United States)

    Mazza, Carlos A; Giménez, Patricia I; Kantolic, Adriana G; Ballaré, Carlos L

    2013-03-01

    Ultraviolet-B radiation (UV-B: 280-315 nm) has damaging effects on cellular components and macromolecules. In plants, natural levels of UV-B can reduce leaf area expansion and growth, which can lead to reduced productivity and yield. UV-B can also have important effects on herbivorous insects. Owing to the successful implementation of the Montreal Protocol, current models predict that clear-sky levels of UV-B radiation will decline during this century in response to ozone recovery. However, because of climate change and changes in land use practices, future trends in UV doses are difficult to predict. In the experiments reported here, we used an exclusion approach to study the effects of solar UV-B radiation on soybean crops, which are extensively grown in many areas of the world that may be affected by future variations in UV-B radiation. In a first experiment, performed under normal management practices (which included chemical pest control), we found that natural levels of UV-B radiation reduced soybean yield. In a second experiment, where no pesticides were applied, we found that solar UV-B significantly reduced insect herbivory and, surprisingly, caused a concomitant increase in crop yield. Our data support the idea that UV-B effects on agroecosystems are the result of complex interactions involving multiple trophic levels. A better understanding of the mechanisms that mediate the anti-herbivore effect of UV-B radiation may be used to design crop varieties with improved adaptation to the cropping systems that are likely to prevail in the coming decades in response to agricultural intensification. Copyright © Physiologia Plantarum 2012.

  16. UV resistibility of a nano-ZnO/glass fibre reinforced epoxy composite

    International Nuclear Information System (INIS)

    Wong, Tsz-ting; Lau, Kin-tak; Tam, Wai-yin; Leng, Jinsong; Etches, Julie A.

    2014-01-01

    Highlights: • A GFRE composite with UV resistibility is introduced. • The bonding behaviour and UV resistibility of the composite were studied upon the addition of nano-ZnO particles. • The solvent effect in the dispersion of nano-ZnO particles was also studied. • The nano-ZnO/GFRE composite shows effective UV absorption with enhanced bonding behaviour. - Abstract: The harmfulness of ultraviolet (UV) radiation (UVR) to human health and polymer degradation has been the focus recently in all engineering industries. A polymer-based composite filled with nano-ZnO particles can enhance its UV resistibility. It has been found that the use of appropriate amount of nano-ZnO/Isopropyl alcohol solvent to prepare a UV resistant nano-ZnO/glass fibre reinforced epoxy (ZGFRE) composite can effectively block the UV transmission with negligible influence on the crystal structure of its resin system. This paper aims at investigating the interfacial bonding behaviour and UV resistibility of a ZGFRE composite. The solvent effect in relation to the dispersion properties of ZnO in the composite is also discussed. XRD results indicated that 20 wt% Isopropyl alcohol was an effective solvent for filling nano-ZnO particles into an epoxy. SEM examination also showed that the bonding behaviour between glass fibre and matrix was enhanced after filling 20 wt% nano-ZnO particles with 20 wt% Isopropyl alcohol into the composite. Samples filled with 20 wt% nano-ZnO/Isopropyl alcohol and 40 wt% nano-ZnO/Isopropyl alcohol has full absorption of UVA (315–400 nm), UVB (280315 nm) and a part of UVC (190–280 nm)

  17. 7 CFR 1205.315 - Marketing.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Marketing. 1205.315 Section 1205.315 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... Research and Promotion Order Definitions § 1205.315 Marketing. Marketing includes the sale of cotton or the...

  18. 15 CFR 280.210 - Discovery.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Discovery. 280.210 Section 280.210... STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE ACCREDITATION AND ASSESSMENT PROGRAMS FASTENER QUALITY Enforcement § 280.210 Discovery. (a) General. The parties are encouraged to engage in voluntary discovery...

  19. 21 CFR 315.2 - Definition.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Definition. 315.2 Section 315.2 Food and Drugs... DIAGNOSTIC RADIOPHARMACEUTICALS § 315.2 Definition. For purposes of this part, diagnostic radiopharmaceutical means: (a) An article that is intended for use in the diagnosis or monitoring of a disease or a...

  20. 15 CFR 315.3 - Application.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Application. 315.3 Section 315.3...-VEHICLE MANUFACTURER § 315.3 Application. Any person in the United States desiring to be determined a bona... in accordance with the instructions set forth on the form and this part. Application forms may be...

  1. 15 CFR 280.208 - Default.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Default. 280.208 Section 280.208... Enforcement § 280.208 Default. (a) General. Failure of the respondent to file an answer within the time...) Petition to set aside default—(1) Procedure. Upon petition filed by a respondent against whom a default...

  2. 15 CFR 280.219 - Settlement.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Settlement. 280.219 Section 280.219... Enforcement § 280.219 Settlement. (a) Cases may be settled before service of a charging letter. In cases in which settlement is reached before service of a charging letter, a proposed charging letter will be...

  3. The effect of exposure to enhanced UV-B radiation on the penetration of monochromatic and polychromatic UV-B radiation in leaves of Brassica napus

    International Nuclear Information System (INIS)

    Cen, Y.-P.; Bornman, J.F.

    1993-01-01

    Using quartz optical fibres, penetration of both monochromatic (310 nm) and polychromatic UV-B (280–320 nm) radiation in leaves of Brassica napus L. (cv. Ceres) was measured. Plants were grown under either visible light (750 μmol m −2 s −1 photosynthetically active radiation) or with the addition of 8. 9 KJ m −2 day −1 biologically effective UV-B (UV-B BE ) radiation. Results showed that of the 310 nm radiation that penetreated the leaf, 90% was within the intial one third of the leaf with high attenuation in the leaf epidermis, especially in UV-treated plants. Polychromatic UV-B radiation, relative to incident radiation, showed a relatively uniform spectral distribution within the leaf, except for collimated radiation. Over 30% of the UV-screening pigments in the leaf, including flavonoids, were found in the adaxial epidermal layer, making this layer less transparent to UV-B radiation than the abaxial epidermis, which contained less than 12% of the UV-screening pigments. UV-screening pigments increased by 20% in UV-treated leaves relative to control leaves. Densely arranged epicuticular wax on the adaxial leaf surface of UV-treated plants may have further decreased penetration of UV-B radiation by reflectance. An increased leaf thickness, and decreases in leaf area and leaf dry weight were also found for UV-treated plants. (author)

  4. Ultraviolet action spectra for aerobic and anaerobic inactivation of Escherichia coli strains specifically sensitive and resistant to near ultraviolet radiations

    International Nuclear Information System (INIS)

    Peak, J.G.; Peak, M.J.; Tuveson, R.W.

    1983-01-01

    Action spectra for the lethal effects of ultraviolet light (254-434 nm) irradiation delivered under aerobic or anaerobic conditions to Escherichia coli RT2 (specifically sensitive to near-UV radiation; > 320 nm) and E. coli RT4 (near-UV resistant) were prepared. Negligible oxygen dependence was observed for both strains below about 315 nm. The oxygen enhancement ratio (OER) for RT4 increased above this wavelength to the longest wavelength used, whereas for RT2 there was a greater increase in the OER to a large peak at 365 nm, then a progressive decrease at longer wavelengths. The results are consistent with the possibility that the sensitivity of strain RT2 to near-UV radiation may be due to hyperproduction of photosensitizer, operating via photodynamic type reactions involving excited species of oxygen. (author)

  5. Investigating Degradation Mechanisms in 130 nm and 90 nm Commercial CMOS Technologies Under Extreme Radiation Conditions

    Science.gov (United States)

    Ratti, Lodovico; Gaioni, Luigi; Manghisoni, Massimo; Traversi, Gianluca; Pantano, Devis

    2008-08-01

    The purpose of this paper is to study the mechanisms underlying performance degradation in 130 nm and 90 nm commercial CMOS technologies exposed to high doses of ionizing radiation. The investigation has been mainly focused on their noise properties in view of applications to the design of low-noise, low-power analog circuits to be operated in harsh environment. Experimental data support the hypothesis that charge trapping in shallow trench isolation (STI), besides degrading the static characteristics of interdigitated NMOS transistors, also affects their noise performances in a substantial fashion. The model discussed in this paper, presented in a previous work focused on CMOS devices irradiated with a 10 Mrad(SiO2) gamma -ray dose, has been applied here also to transistors exposed to much higher (up to 100 Mrad(SiO2 )) doses of X-rays. Such a model is able to account for the extent of the observed noise degradation as a function of the device polarity, dimensions and operating point.

  6. Overview of the molecular defense systems used by sea urchin embryos to cope with UV radiation.

    Science.gov (United States)

    Bonaventura, Rosa; Matranga, Valeria

    2017-07-01

    The sea urchin embryo is a well-recognized developmental biology model and its use in toxicological studies has been widely appreciated. Many studies have focused on the evaluation of the effects of chemical stressors and their mixture in marine ecosystems using sea urchin embryos. These are well equipped with defense genes used to cope with chemical stressors. Recently, ultraviolet radiation (UVR), particularly UVB (280-315 nm), received more attention as a physical stressor. Mainly in the Polar Regions, but also at temperate latitudes, the penetration of UVB into the oceans increases as a consequence of the reduction of the Earth's ozone layer. In general, UVR induces oxidative stress in marine organisms affecting molecular targets such as DNA, proteins, and lipids. Depending on the UVR dose, developing sea urchin embryos show morphological perturbations affecting mainly the skeleton formation and patterning. Nevertheless, embryos are able to protect themselves against excessive UVR, using mechanisms acting at different levels: transcriptional, translational and post-translational. In this review, we recommend the sea urchin embryo as a suitable model for testing physical stressors such as UVR and summarize the mechanisms adopted to deal with UVR. Moreover, we review UV-induced apoptotic events and the combined effects of UVR and other stressors. Copyright © 2016 Elsevier Ltd. All rights reserved.

  7. Effect of UV Radiation by Projectors on 3D Printing

    Directory of Open Access Journals (Sweden)

    Kovalenko Iaroslav

    2017-01-01

    Full Text Available Polymers that solidify under light radiation are commonly used in digital light processing (DLP 3D printing. A wide range of photopolymers use photoinitiators that react to radiation in range of ultraviolet (UV wavelength. In the present study we provided measurement of radiant fluence in the UV wavelength range from 280 nm to 400 nm for two data projectors and compared effect of radiation on quality of 3D printing. One projector is commonly used DLP projector with high energy lamp. Second one is an industrial projector, in which RGB light emitting diodes (LEDs are replaced by UV LEDs with wattage at the level of 3.6 % of the first one. Achieved data confirmed uneven distribution of radiant energy on illuminated area. These results validate, that undesired heating light causes internal stress inside built models that causes defects in final products.

  8. Photosensitized inactivation of DNA by monochromatic 334-nm radiation in the presence of 2-thiouracil: genetic activity and backbone breaks

    International Nuclear Information System (INIS)

    Peak, M.J.; Ito, A.; Peak, J.G.; Foote, C.S.

    1988-01-01

    Monochromatic 334-nm radiation delivered under aerobic conditions inactivates the genetic activity (ability to transform auxotrophic recipient cells to nutritional prototrophy) of isolated transforming Bacillus subtilis DNA. The presence of superoxide dismutase (SOD), catalase, and mannitol reduces the 334-nm inactivation. The rate of inactivation of the genetic activity by 334-nm radiation is enhanced fivefold by the sensitizer 2-thiouracil (s 2 Ura). This enhancement is substantially reversed when the irradiations are performed in the presence of mannitol, and, to a lesser extent, SOD. Catalase slightly reduces the s 2 Ura enhancement of 334-nm inactivation of transforming activity. Backbone breaks induced in the same DNA by aerobic 334-nm radiation were also enhanced markedly by the presence of s 2 Ura; this enhancement was reversed by the presence of mannitol and, to a lesser extent, SOD during irradiation. Catalase had no effect upon s 2 Ura-enhanced, 334-nm-induced SSBs. Whereas DNA breakage may be responsible for a portion of the inactivation of the DNA by the photosensitized reaction between s 2 Ura and 334-nm radiation, it is not the only inactivating lesion, because the yield of SSBs per lethal hit per unit length of DNA is not constant for all the irradiation conditions studied. (author)

  9. Investigation of 207 nm UV radiation for degradation of organic dye ...

    African Journals Online (AJOL)

    The photo-degradation of organic dye C.I. Acid Red 213 (AR-213) was achieved by 207 nm UV radiation emitted from a planar KrBr* excimer lamp without addition of oxidants at varying initial pH values. Precipitates were found to be generated when the irradiated solution of initial acid pH was adjusted to alkaline pH and ...

  10. Photoluminescence emission spectra of Makrofol® DE 1-1 upon irradiation with ultraviolet radiation

    Science.gov (United States)

    El Ghazaly, M.; Aydarous, Abdulkadir

    Photoluminescence (PL) emission spectra of Makrofol® DE 1-1 (bisphenol-A based polycarbonate) upon irradiation with ultraviolet radiation of different wavelengths were investigated. The absorption-and attenuation coefficient measurements revealed that the Makrofol® DE 1-1 is characterized by high absorbance in the energy range 6.53-4.43 eV but for a lower energy than 4.43 eV, it is approximately transparent. Makrofol® DE 1-1 samples were irradiated with ultraviolet radiation of wavelength in the range from 250 (4.28 eV) to 400 (3.10 eV) nm in step of 10 nm and the corresponding photoluminescence (PL) emission spectra were measured with a spectrofluorometer. It is found that the integrated counts and the peak height of the photoluminescence emission (PL) bands are strongly correlated with the ultraviolet radiation wavelength. They are increased at the ultraviolet radiation wavelength 280 nm and have maximum at 290 nm, thereafter they decrease and diminish at 360 nm of ultraviolet wavelength. The position of the PL emission band peak was red shifted starting from 300 nm, which increased with the increase the ultraviolet radiation wavelength. The PL bandwidth increases linearly with the increase of the ultraviolet radiation wavelength. When Makrofol® DE 1-1 is irradiated with ultraviolet radiation of short wavelength (UVC), the photoluminescence emission spectra peaks also occur in the UVC but of a relatively longer wavelength. The current new findings should be considered carefully when using Makrofol® DE 1-1 in medical applications related to ultraviolet radiation.

  11. 7 CFR 58.315 - Continuous churns.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Continuous churns. 58.315 Section 58.315 Agriculture....315 Continuous churns. All product contact surfaces of the churn and related equipment shall be of..., Rubber, and Rubber-Like Materials. All product contact surfaces of the churn and related equipment shall...

  12. 31 CFR 536.315 - United States.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false United States. 536.315 Section 536.315 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF... Definitions § 536.315 United States. The term United States means the United States, its territories and...

  13. 7 CFR 1210.315 - United States.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false United States. 1210.315 Section 1210.315 Agriculture... PLAN Watermelon Research and Promotion Plan Definitions § 1210.315 United States. United States means each of the several States and the District of Columbia. [60 FR 10797, Feb. 28, 1995] National...

  14. 21 CFR 357.280 - Professional labeling.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Professional labeling. 357.280 Section 357.280 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS... Drug Products § 357.280 Professional labeling. The labeling provided to health professionals (but not...

  15. 21 CFR 333.280 - Professional labeling.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Professional labeling. 333.280 Section 333.280 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS... Drug Products § 333.280 Professional labeling. The labeling provided to health professionals (but not...

  16. 24 CFR 280.20 - Home quality.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Home quality. 280.20 Section 280.20 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF... GRANT PROGRAMS NEHEMIAH HOUSING OPPORTUNITY GRANTS PROGRAM § 280.20 Home quality. (a) Generally. Except...

  17. 40 CFR 280.102 - Trust fund.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 26 2010-07-01 2010-07-01 false Trust fund. 280.102 Section 280.102 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) TECHNICAL STANDARDS AND CORRECTIVE ACTION REQUIREMENTS FOR OWNERS AND OPERATORS OF UNDERGROUND STORAGE TANKS (UST) Financial Responsibility § 280.102 Trust...

  18. A monolithic active pixel sensor for ionizing radiation using a 180 nm HV-SOI process

    Energy Technology Data Exchange (ETDEWEB)

    Hemperek, Tomasz; Kishishita, Tetsuichi; Krueger, Hans; Wermes, Norbert [Institute of Physics, University of Bonn, Bonn (Germany)

    2016-07-01

    An improved SOI-MAPS (Silicon On Insulator Monolithic Active Pixel Sensor) for ionizing radiation based on thick-180 nm High Voltage SOI technology (HV-SOI) has been developed. Similar to existing Fully Depleted SOI-based (FD-SOI) MAPS, a buried silicon oxide inter-dielectric (BOX) layer is used to separate the CMOS electronics from the handle wafer which is used as a depleted charge collection layer. Standard FD-SOI MAPS suffer from radiation damage such as transistor threshold voltage shifts due to trapped charge in the buried oxide layer and charged interface states created at the silicon oxide boundaries (back gate effect). The X-FAB 180 nm HV-SOI technology offers an additional isolation using a deep non-depleted implant between the BOX layer and the active circuitry which mitigates this problem. Therefore we see in this technology a high potential to implement radiation-tolerant MAPS with fast charge collection. The design and measurement results from first prototypes are presented including radiation tolerance to total ionizing dose and charge collection properties of neutron irradiated samples.

  19. Radiation types and their influence on thermoluminescence of materials

    International Nuclear Information System (INIS)

    Soika, C.; Delincee, H.

    1999-01-01

    The paper reports experiments investigating pure minerals (quartz and potash feldspar) and a mixture (sand) and their luminescence under the impact of various types of radiation. The materials were exposed to the radiation types commonly used for radiation treatment of food: 5 and 10 MeV electron radiation, 6 0Co-γ radiation with applied doses of 0.2 and 5.0 kGy. After measurements, the samples were normalized by re-irradiation with 2, 5, and 10 MeV electrons as well as β radiation ( 9 0Sr), γ radiation ( 6 0Co), and UV-C light (200-280 nm), applying radiation doses of 0.25 kGy and 1.0 kGy, or 0.5 J/cm 2 , respectively. The analysis of the first and second glow curves of each material showed that the radiation type determines the glow curve. UV light was found to be inappropriate for normalisation of those samples containing only quartz as a luminescent constituent. (orig./CB) [de

  20. 47 CFR 25.280 - Inclined orbit operations.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Inclined orbit operations. 25.280 Section 25.280 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES SATELLITE COMMUNICATIONS Technical Operations § 25.280 Inclined orbit operations. (a) Satellite operators may commence...

  1. Mode-locked Ti:sapphire laser oscillators pumped by wavelength-multiplexed laser diodes

    Science.gov (United States)

    Sugiyama, Naoto; Tanaka, Hiroki; Kannari, Fumihiko

    2018-05-01

    We directly pumped a Ti:sapphire laser by combining 478 and 520 nm laser diodes to prevent the effect of absorption loss induced by the pump laser of shorter wavelengths (∼450 nm). We obtain a continuous-wave output power of 660 mW at a total incident pump power of 3.15 W. We demonstrate mode locking using a semiconductor saturable absorber mirror, and 126 fs pulses were obtained at a repetition rate of 192 MHz. At the maximum pump power, the average output power is 315 mW. Shorter mode-locked pulses of 42 and 48 fs were respectively achieved by Kerr-lens mode locking with average output powers of 280 and 360 mW at a repetition rate of 117 MHz.

  2. New silicon photodiodes for detection of the 1064nm wavelength radiation

    Science.gov (United States)

    Wegrzecki, Maciej; Piotrowski, Tadeusz; Puzewicz, Zbigniew; Bar, Jan; Czarnota, Ryszard; Dobrowolski, Rafal; Klimov, Andrii; Kulawik, Jan; Kłos, Helena; Marchewka, Michał; Nieprzecki, Marek; Panas, Andrzej; Seredyński, Bartłomiej; Sierakowski, Andrzej; Słysz, Wojciech; Synkiewicz, Beata; Szmigiel, Dariusz; Zaborowski, Michał

    2016-12-01

    In this paper a concept of a new bulk structure of p+-υ-n+ silicon photodiodes optimized for the detection of fast-changing radiation at the 1064 nm wavelength is presented. The design and technology for two types of quadrant photodiodes, the 8-segment photodiode and the 32-element linear photodiode array that were developed according to the concept are described. Electric and photoelectric parameters of the photodiodes mentioned above are presented.

  3. 20 CFR 726.315 - Contents.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Contents. 726.315 Section 726.315 Employees' Benefits EMPLOYMENT STANDARDS ADMINISTRATION, DEPARTMENT OF LABOR FEDERAL COAL MINE HEALTH AND SAFETY ACT OF 1969, AS AMENDED BLACK LUNG BENEFITS; REQUIREMENTS FOR COAL MINE OPERATOR'S INSURANCE Civil Money...

  4. 13 CFR 315.15 - Conflicts of interest.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Conflicts of interest. 315.15 Section 315.15 Business Credit and Assistance ECONOMIC DEVELOPMENT ADMINISTRATION, DEPARTMENT OF COMMERCE TRADE ADJUSTMENT ASSISTANCE FOR FIRMS Protective Provisions § 315.15 Conflicts of interest. EDA will...

  5. 15 CFR 280.201 - Violations.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Violations. 280.201 Section 280.201 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade NATIONAL INSTITUTE OF... otherwise, fasteners that are required by the applicable consensus standard or standards to bear an insignia...

  6. 7 CFR 3.15 - Liquidation of collateral.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Liquidation of collateral. 3.15 Section 3.15... and Compromise of Claims § 3.15 Liquidation of collateral. (a) In accordance with applicable statutes and regulations, agencies may liquidate security or collateral through a sale or a nonjudicial...

  7. Ion beam induced luminescence: Relevance to radiation induced bystander effects

    Energy Technology Data Exchange (ETDEWEB)

    Ahmad, S.B., E-mail: ahmad.rabilal@gmail.com [Medical Physics and Applied Radiation Sciences, University of McMaster, Hamilton, Ontario (Canada); McNeill, F.E., E-mail: fmcneill@mcmaster.ca [Medical Physics and Applied Radiation Sciences, University of McMaster, Hamilton, Ontario (Canada); Byun, S.H., E-mail: soohyun@mcmaster.ca [Medical Physics and Applied Radiation Sciences, University of McMaster, Hamilton, Ontario (Canada); Prestwich, W.V., E-mail: prestwic@mcmaster.ca [Medical Physics and Applied Radiation Sciences, University of McMaster, Hamilton, Ontario (Canada); Seymour, C., E-mail: seymouc@mcmaster.ca [Medical Physics and Applied Radiation Sciences, University of McMaster, Hamilton, Ontario (Canada); Mothersill, C.E., E-mail: mothers@mcmaster.ca [Medical Physics and Applied Radiation Sciences, University of McMaster, Hamilton, Ontario (Canada)

    2012-10-01

    The aim of this work is quantify the light emitted as a result of charged particle interaction in materials which may be of relevance to radiation induced 'bystander effects' studies. We have developed a system which employs single photon counting to measure the light emitted from samples irradiated under vacuum by a charged particle beam. The system uses a fast photomultiplier tube with a peak cathode response at 420 nm. It has been tested in a proof-of-principle experiment using polystyrene targets. Light output, as a result of irradiation, was measured. The luminescence yield appears to have a non-linear behavior with the incident ion fluence: it rises exponentially to an asymptotic value. The target was irradiated with beam energies varying from 1 to 2 MeV and showed saturation at or before an incident fluence rate of 3 Multiplication-Sign 10{sup 13} H{sup +}/cm{sup 2} s. The average saturation value for the photon output was found to be 40 Multiplication-Sign 10{sup 6} cps. Some measurements were performed using filters to study the emission at specific wavelengths. In the case of filtered light measurements, the photon output was found to saturate at 28 Multiplication-Sign 10{sup 3}, 10 Multiplication-Sign 10{sup 6}, and 35 Multiplication-Sign 10{sup 6} cps for wavelengths of 280 {+-} 5 nm, 320 {+-} 5 nm and 340 {+-} 5 nm respectively. The light output reaches a maximum value because of damage induced in the polymer. Our measurements indicate a 'damage cross section' of the order of 10{sup -14} cm{sup 2}. The average radiant intensity was found to increase at wavelengths of 280 and 320 nm when the proton energy was increased. This was not found to occur at 340 nm. In conclusion, the light emission at specific wavelengths was found to depend upon the incident proton fluence and the proton energy. The wavelengths of the emitted light measured in this study have significance for the understanding of radiation induced bystander effects.

  8. Ion beam induced luminescence: Relevance to radiation induced bystander effects

    Science.gov (United States)

    Ahmad, S. B.; McNeill, F. E.; Byun, S. H.; Prestwich, W. V.; Seymour, C.; Mothersill, C. E.

    2012-10-01

    The aim of this work is quantify the light emitted as a result of charged particle interaction in materials which may be of relevance to radiation induced "bystander effects" studies. We have developed a system which employs single photon counting to measure the light emitted from samples irradiated under vacuum by a charged particle beam. The system uses a fast photomultiplier tube with a peak cathode response at 420 nm. It has been tested in a proof-of-principle experiment using polystyrene targets. Light output, as a result of irradiation, was measured. The luminescence yield appears to have a non-linear behavior with the incident ion fluence: it rises exponentially to an asymptotic value. The target was irradiated with beam energies varying from 1 to 2 MeV and showed saturation at or before an incident fluence rate of 3 × 1013 H+/cm2 s. The average saturation value for the photon output was found to be 40 × 106 cps. Some measurements were performed using filters to study the emission at specific wavelengths. In the case of filtered light measurements, the photon output was found to saturate at 28 × 103, 10 × 106, and 35 × 106 cps for wavelengths of 280 ± 5 nm, 320 ± 5 nm and 340 ± 5 nm respectively. The light output reaches a maximum value because of damage induced in the polymer. Our measurements indicate a "damage cross section" of the order of 10-14 cm2. The average radiant intensity was found to increase at wavelengths of 280 and 320 nm when the proton energy was increased. This was not found to occur at 340 nm. In conclusion, the light emission at specific wavelengths was found to depend upon the incident proton fluence and the proton energy. The wavelengths of the emitted light measured in this study have significance for the understanding of radiation induced bystander effects.

  9. 21 CFR 315.6 - Evaluation of safety.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Evaluation of safety. 315.6 Section 315.6 Food and... USE DIAGNOSTIC RADIOPHARMACEUTICALS § 315.6 Evaluation of safety. (a) Factors considered in the safety...)(1) To establish the safety of a diagnostic radiopharmaceutical, FDA may require, among other...

  10. 46 CFR 280.6 - Calendar year accounting.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Calendar year accounting. 280.6 Section 280.6 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION REGULATIONS AFFECTING SUBSIDIZED VESSELS AND... Calendar year accounting. Except as provided in § 280.9 (relating to the final year of an ODS agreement...

  11. Photoluminescence emission spectra of Makrofol® DE 1-1 upon irradiation with ultraviolet radiation

    Directory of Open Access Journals (Sweden)

    M. El Ghazaly

    Full Text Available Photoluminescence (PL emission spectra of Makrofol® DE 1-1 (bisphenol-A based polycarbonate upon irradiation with ultraviolet radiation of different wavelengths were investigated. The absorption-and attenuation coefficient measurements revealed that the Makrofol® DE 1-1 is characterized by high absorbance in the energy range 6.53–4.43 eV but for a lower energy than 4.43 eV, it is approximately transparent. Makrofol® DE 1-1 samples were irradiated with ultraviolet radiation of wavelength in the range from 250 (4.28 eV to 400 (3.10 eV nm in step of 10 nm and the corresponding photoluminescence (PL emission spectra were measured with a spectrofluorometer. It is found that the integrated counts and the peak height of the photoluminescence emission (PL bands are strongly correlated with the ultraviolet radiation wavelength. They are increased at the ultraviolet radiation wavelength 280 nm and have maximum at 290 nm, thereafter they decrease and diminish at 360 nm of ultraviolet wavelength. The position of the PL emission band peak was red shifted starting from 300 nm, which increased with the increase the ultraviolet radiation wavelength. The PL bandwidth increases linearly with the increase of the ultraviolet radiation wavelength. When Makrofol® DE 1-1 is irradiated with ultraviolet radiation of short wavelength (UVC, the photoluminescence emission spectra peaks also occur in the UVC but of a relatively longer wavelength. The current new findings should be considered carefully when using Makrofol® DE 1-1 in medical applications related to ultraviolet radiation. Keywords: Photoluminescence spectra, Makrofol® DE 1-1, UV–vis spectrophotometry, Attenuation coefficient, Ultraviolet radiation

  12. 46 CFR 153.280 - Piping system design.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Piping system design. 153.280 Section 153.280 Shipping... BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Piping Systems and Cargo Handling Equipment § 153.280 Piping system design. (a) Each cargo piping system must meet...

  13. 21 CFR 73.315 - Corn endosperm oil.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Corn endosperm oil. 73.315 Section 73.315 Food and... ADDITIVES EXEMPT FROM CERTIFICATION Foods § 73.315 Corn endosperm oil. (a) Identity. (1) The color additive corn endosperm oil is a reddish-brown liquid composed chiefly of glycerides, fatty acids, sitosterols...

  14. 31 CFR 315.61 - Payment after death.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Payment after death. 315.61 Section 315.61 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL..., Absentees, et al. § 315.61 Payment after death. After the death of the ward, and at any time prior to the...

  15. Anthropogenic changes in the surface all-sky UV-B radiation through 1850-2005 simulated by an Earth system model

    Science.gov (United States)

    Watanabe, S.; Takemura, T.; Sudo, K.; Yokohata, T.; Kawase, H.

    2012-06-01

    The historical anthropogenic change in the surface all-sky UV-B (solar ultraviolet: 280-315 nm) radiation through 1850-2005 is evaluated using an Earth system model. Responses of UV-B dose to anthropogenic changes in ozone and aerosols are separately evaluated using a series of historical simulations including/excluding these changes. Increases in these air pollutants cause reductions in UV-B transmittance, which occur gradually/rapidly before/after 1950 in and downwind of industrial and deforestation regions. Furthermore, changes in ozone transport in the lower stratosphere, which is induced by increasing greenhouse gas concentrations, increase ozone concentration in the extratropical upper troposphere and lower stratosphere. These transient changes work to decrease the amount of UV-B reaching the Earth's surface, counteracting the well-known effect increasing UV-B due to stratospheric ozone depletion, which developed rapidly after ca. 1980. As a consequence, the surface UV-B radiation change between 1850 and 2000 is negative in the tropics and NH extratropics and positive in the SH extratropics. Comparing the contributions of ozone and aerosol changes to the UV-B change, the transient change in ozone absorption of UV-B mainly determines the total change in the surface UV-B radiation at most locations. On the other hand, the aerosol direct and indirect effects on UV-B play an equally important role to that of ozone in the NH mid-latitudes and tropics. A typical example is East Asia (25° N-60° N and 120° E-150° E), where the effect of aerosols (ca. 70%) dominates the total UV-B change.

  16. Preparation and Characterization of Bragg Fibers for Delivery of Laser Radiation at 1064 nm

    Directory of Open Access Journals (Sweden)

    V. Matejec

    2013-04-01

    Full Text Available Bragg fibers offer new performance for transmission of high laser energies over long distances. In this paper theoretical modeling, preparation and characterization of Bragg fibers for delivery laser radiation at 1064 nm are presented. Investigated Bragg fibers consist of the fiber core with a refractive index equal to that of silica which is surrounded by three pairs of circular layers. Each pair is composed of one layer with a high and one layer with a low refractive index and characterized by a refractive-index difference around 0.03. Propagation constants and radiation losses of the fundamental mode in such a structure were calculated on the basis of waveguide optics. Preforms of the Bragg fibers were prepared by the MCVD method using germanium dioxide, phosphorous pentoxide and fluorine as silica dopants. The fibers with a diameter of 170 m were drawn from the preforms. Refractive-index profiles, angular distributions of the output power and optical losses of the prepared fibers were measured. Results of testing the fibers for delivery radiation of a pulse Nd:YAG laser at 1064 nm are also shown.

  17. Generation of continuous-wave single-frequency 1.5 W 378 nm radiation by frequency doubling of a Ti:sapphire laser.

    Science.gov (United States)

    Cha, Yong-Ho; Ko, Kwang-Hoon; Lim, Gwon; Han, Jae-Min; Park, Hyun-Min; Kim, Taek-Soo; Jeong, Do-Young

    2010-03-20

    We have generated continuous-wave single-frequency 1.5 W 378 nm radiation by frequency doubling a high-power Ti:sapphire laser in an external enhancement cavity. An LBO crystal that is Brewster-cut and antireflection coated on both ends is used for a long-term stable frequency doubling. By optimizing the input coupler's reflectivity, we could generate 1.5 W 378 nm radiation from a 5 W 756 nm Ti:sapphire laser. According to our knowledge, this is the highest CW frequency-doubled power of a Ti:sapphire laser.

  18. New apparatus with high radiation energy between 320 to 460 nm: physical description and dermatological applications

    International Nuclear Information System (INIS)

    Mutzhas, M.F.; Holzle, E.; Hofmann, C.; Plewig, G.

    1981-01-01

    A new apparatus (UVASUN 5000) is presented with high radiation energy between 320 to 460 nm. The radiator is a specially developed source for high uv-A intensity, housing a quartz bulb with a mixture of argon, mercury and metal-halides. The uv-A energy in the range of 320 to 400 nm is about 84% of the total radiation energy. Effects of very high doses of uv-A on human skin were studied. Following single uv-A applications the minimal tanning dose uv-A (MTD) and the immediate pigment darkening (IPD) dose of uv-A were established. Repeated exposure to this uv-A delivering system yields long lasting dark brown skin pigmentation without any clinical or histological signs of sunburn (uv-B) damage, epidermal hyperplasia or thickening of the stratum corneum. Minimal therapeutic results were seen in the phototherapy of vitiligo and inflammatory acne

  19. 8 CFR 280.21 - Seizure of aircraft.

    Science.gov (United States)

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Seizure of aircraft. 280.21 Section 280.21... OF FINES § 280.21 Seizure of aircraft. Seizure of an aircraft under the authority of section 239 of... than the amount of the fine which may be imposed. If seizure of an aircraft for violation of section...

  20. Spectral composition of shortwave radiation reflected and deep penetrating into snow near the Barentsburg settlement (Svalbard

    Directory of Open Access Journals (Sweden)

    P. N. Svyashchennikov

    2015-01-01

    Full Text Available Data on spectral composition of shortwave radiation that is reflected from snow and penetrates deep into the snow cover obtained near the Barentsburg settlement (Svalbard are discussed in the paper. Measurements were made by the use of the spectral radiometer TriOS Ramses within the wavelength range of 280–950 nm. The results will allow more proper taking account of the anthropogenic pollution effects on the radiative properties of snow cover under conditions of industrial activity related to the coal extraction and burning in Barentsburg.

  1. Mutation induction by 365-nm radiation and far-ultraviolet light in Escherichia coli differing in near- and far-ultraviolet light sensitivity

    International Nuclear Information System (INIS)

    Leonardo, J.M.; Reynolds, P.R.; Tuveson, R.W.

    1984-01-01

    The his-4 locus derived from Escherichia coli strain AB1157 has been transduced into 4 E. coli strains that exhibit all 4 possible combinations of genes controlling sensitivity to near-ultraviolet light (nur versus nur + ) and far-ultraviolet light (uvrA6 versus uvrA + ). The 4 strains exhibited the predicted sensitivity to 254-nm radiation based on the sensitivity of the parent strains from which they were derived and the frequency of his + mutations predicted from experiments with AB1157 from which the his-4 locus was derived. When the 4 strains were treated with 365-nm radiation, they exhibited the predicted sensitivity based on the near-ultraviolet light sensitivity of the strains from which they were derived while his + mutations were undetectable with the 4 strains as well as with strain AB1157. When treated with 365-nm radiation, cells of a WP2sub(s) strain (a derivative of B/r transduced to his-4) plated on semi-enriched medium prepared with casamino acids did not yield induced mutations, whereas plating on semi-enriched medium prepared with nutrient broth did yield mutants at both the his-4 and trp loci at frequencies at least an order of magnitude lower than that observed with far-ultraviolet light. The induction of nutritionally independent mutants by 365-nm radiation is strongly dependent on the supplement used for semi-enrichment. When compared at equivalent survival levels, mutant frequencies are significantly less following 365-nm radiation when compared with far-ultraviolet radiation. (Auth.)

  2. The effect of UV-B and UV-C radiation on Hibiscus leaves determined by ultraweak luminescence and fluorescence induction [chlorophyll fluorescence induction, ultraweak luminescence

    International Nuclear Information System (INIS)

    Panagopoulos, I.; Bornman, J.F.; Björn, L.O.

    1989-01-01

    The effects of UV-C (254 nm) and UV-B (280-320 nm) on chlorophyll fluorescence induction and ultraweak luminescence (UL) in detached leaves of Hibiscus rosa-sinensis L. were investigated. UL from leaves exposed to UV-B and UV-C radiation reached a maximum 72 h after irradiation. In both cases most of the light was of a wavelength over 600 nm. An increase in the percentage of long wavelength light with time was detected. UV radiation increased peroxidase activity, which also reached a maximum 72 h after irradiation. UV-B and UV-C both reduced variable chlorophyll fluorescence. No effect on the amount of chlorophyll or UV screening pigments was observed with the short-term irradiation used in this investigation. (author)

  3. New apparatus with high radiation energy between 320-460 nm: physical description and dermatological applications

    International Nuclear Information System (INIS)

    Mutzhas, M.F.; Holzle, E.; Hofmann, C.; Plewig, G.

    1981-01-01

    A new apparatus (UVASUN 5000) is presented with high-radiation energy between 320 to 460 nm. The measureable energy below 320 nm was shown to be many orders of magnitude too low to produce erythema. The radiator is a specially developed source for high uv-A intensity, housing a quartz bulb with a mixture of argon, mercury and metal-halides. At a skin-target distance of 0.2 m the size of the irradiated area is 0.35 x 0.35 m, and the measured mean uv-A intensity is about 1400 W. m-2 (140 mW . cm-2). The uv-A energy in the range of 320 to 400 nm is about 84% of the total radiation energy. Effects of very high doses of uv-A on human skin were studied. Following single uv-a applications the minimal tanning dose uv-A (MTD) and the immediate pigment darkening (IPD) dose of uv-A were established. The calculated IPD threshold time was 1.8 min at 0.2 m. Repeated exposure to this uv-A delivering system yields long lasting dark brown skin pigmentation without any clinical or histological signs of sunburn (uv-B) damage, epidermal hyperplasia or thickening of the stratum corneum. The instrument was also successfully used for photo-patch testing and reproduction of skin lesions of polymorphous light eruption. Minimal therapeutic results were seen in the phototherapy of vitiligo and inflammatory acne

  4. The effects of UV radiation during the vegetative period on antioxidant compounds and postharvest quality of broccoli (Brassica oleracea L.).

    Science.gov (United States)

    Topcu, Yasin; Dogan, Adem; Kasimoglu, Zehra; Sahin-Nadeem, Hilal; Polat, Ersin; Erkan, Mustafa

    2015-08-01

    In this study, the effects of supplementary UV radiation during the vegetative period on antioxidant compounds, antioxidant activity and postharvest quality of broccoli heads during long term storage was studied. The broccolis were grown under three different doses of supplementary UV radiation (2.2, 8.8 and 16.4 kJ/m(2)/day) in a soilless system in a glasshouse. Harvested broccoli heads were stored at 0 °C in modified atmosphere packaging for 60 days. The supplementary UV radiation (280-315 nm) during the vegetative period significantly decreased total carotenoid, the chlorophyll a and chlorophyll b content but increased the ascorbic acid, total phenolic and flavonoid contents of broccolis. All supplementary UV treatments slightly reduced the antioxidant activity of the broccolis, however, no remarkable change was observed between 2.2 and 8.8 kJ/m(2) radiation levels. The sinigrin and glucotropaeolin contents of the broccolis were substantially increased by UV treatments. The prolonged storage period resulted in decreased ascorbic acid, total phenolic and flavonoid contents, as well as antioxidant activity. Discoloration of the heads, due to decreased chlorophyll and carotenoid contents, was also observed with prolonged storage duration. Glucosinolates levels showed an increasing tendency till the 45th day of storage, and then their levels started to decline. The weight loss of broccoli heads during storage progressively increased with storage time in all treatments. Total soluble solids, solids content and titratable acidity decreased continuously during storage. Titratable acidity was not affected by UV radiation doses during the storage time whereas soluble solids and solids content (dry matter) were significantly affected by UV doses. Supplementary UV radiation increased the lightness (L*) and chroma (C*) values of the broccoli heads. Pre-harvest UV radiation during vegetative period seems to be a promising tool for increasing the beneficial health components

  5. Reassessment of the differential effects of ultraviolet and ionizing radiation on HIV promoter: the use of cell survival as the basis for comparisons

    International Nuclear Information System (INIS)

    Beer, J.Z.; Olvey, K.M.; Lee, W.; Zmudzka, B.Z.

    1994-01-01

    Effects of different radiation treatments on the human immunodeficiency virus-1 (HIV) promoter were reassessed for exposures comparable to those encountered in clinical or cosmetic practice, using survival of the host cell as a basis for comparisons. The exposures were performed with two ultraviolet radiation sources commonly used as medical or cosmetic devices (UVASUN 2000 and FS20 lamps), a germicidal (G15T8) lamp and an X-ray machine. The UVC component of the FS20 lamp was filtered out. The emission spectra of the lamps were determined. The characteristics of these sources allowed us to discriminate among effects of UVA1 (340-400 nm), UVB + UVA2 (280-340 nm) and UVC (254 nm) radiations. Effects of irradiation were ascertained using cultures of HeLa cells stably transfected with the HIV promoter linked to a reporter-chloramphenicol acetyl transferase-gene. (Author)

  6. Mutagenicity of monoadducts and cross-links induced in Aspergillus nidulans by 8-methoxypsoralen plus 365 nm radiation

    International Nuclear Information System (INIS)

    Scott, B.R.; Maley, M.A.

    1981-01-01

    8-Methoxypsoralen plus 365 nm radiation induces mutation at the methionine supressor loci of Aspergillus inhibitor-deficient conidia at low doses of near-UV radiation with one-hit kinetics and at higher near-UV radiation doses with two-hit kinetics. These results and others suggest that both monoadducts and cross-links, formed by 8-methoxypsoralen and DNA upon exposure to UV radiation, are capable of inducing mutation. Evidence is also presented that induced furocoumarin cross-links are responsible for the inactivation of the Aspergillus conidium. (author)

  7. 48 CFR 315.372 - Preparation of negotiation memorandum.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Preparation of negotiation memorandum. 315.372 Section 315.372 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Source Selection 315.372 Preparation of negotiation memorandum. The Contracting...

  8. 40 CFR 31.5 - Effect on other issuances.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Effect on other issuances. 31.5 Section 31.5 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE... General § 31.5 Effect on other issuances. All other grants administration provisions of codified program...

  9. Comparative analysis of the effect of the GaAlAs laser irradiation in 780 nm and 660 nm in the hypersensitive dentin; Analise comparativa do efeito da irradiacao do laser de GaAlAs em 780 nm e 660 nm na hipersensibilidade dentinaria

    Energy Technology Data Exchange (ETDEWEB)

    Yuan, Sun Chien

    2003-07-01

    This study was to evaluate and compare the effects of the low intensity in laser radiation among GaAlAs 780 nm and GaAlAs 660 nm. The main proposal is to verify if there is any difference of the effects or results in low intensity laser application treatment of hypersensitive dentin, keeping the same parameters, only differing in wavelength. The samples were distributed in two groups. Group A 90 cases, treated with GaAlAs 780 nm and group B irradiated with GaAlAs 660 nm with a total of 76 cases analyzed. The results of application with GaAlAs 660 nm and GaAlAs 780 nm do not differ statistically. Which means using any one of the irradiation gives the same results. However can be noted that the response of reduction of hypersensitivity is faster with the radiation of GaAlAs 780 nm, but the results after three applications is the same for both types of radiation. (author)

  10. 7 CFR 1493.280 - Evidence of export report.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Evidence of export report. 1493.280 Section 1493.280... OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS CCC EXPORT CREDIT GUARANTEE PROGRAMS CCC Facility Guarantee Program (FGP) Operations § 1493.280 Evidence of export report. (a) Report of export. The...

  11. Multiphoton ionization and fragmentation study of acetone using 308 nm laser radiation

    Science.gov (United States)

    Liu Houxiang, Li Shutao, Han Jingcheng, Zhu Rong, Guan Yifu, Wu Cunkai

    1988-10-01

    Multiphoton ionization and fragmentation (MPI-F) of acetone molecules using 308 nm laser radiation was studied by using a molecular beam and quadrupole mass spectrometer. The ion peaks of acetone molecule appear at m/e=15 and 43, corresponding to the two fragments CH3+ and CH3CO+. It is considered that these two ions are, respectively, formed by direct (2+1) and 2-photon ionization of methyl and acetyl radicals, generated by photodissociation of acetone molecule.

  12. 31 CFR 315.1 - Official agencies.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Official agencies. 315.1 Section 315.1 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE.... Federal Reserve Bank of Kansas City, 925 Grand Avenue, Kansas City, MO 64198 Dallas, San Francisco, Kansas...

  13. Impact of increased ultraviolet-B radiation stress due to stratospheric ozone depletion on N2 fixation in traditional African commercial legumes

    International Nuclear Information System (INIS)

    Chimphango, S.B.M.; Musil, C.F.; Dakora, F.D.

    2004-01-01

    Reports of diminished nodule formation and nitroge-nase activity in some Asian tropical legumes exposed to above-ambient levels of ultraviolet-B (UV-B: 280-315nm) radiation have raised concerns as to the impact of stratospheric ozone depletion on generally poorly developed traditional African farming systems confronted by the high cost and limited availability of chemical fertilisers. These rely on N 2 -fixing legumes as the cheapest source of N for maintaining soil fertility and sustainable yields in the intrinsically infertile and heterogeneous African soils. In view of this, we examined the effects of supplemental UV-B radiation approximating 15% and 25% depletions in the total ozone column on N 2 fixation in eight traditional African commercial legume species representing crop, forest, medicinal, ornamental and pasture categories. In all categories examined, except medicinal, supplemental UV-B had no effect on root non-structural carbohydrates, antho-cyanins and flavonoids, known to signal Rhizobiaceae micro-symbionts and promote nodule formation, or on nodule mass, activity and quantities of N fixed in different plant organs and whole plants. In contrast, in the medicinal category Cyclopia maculata (Honeybush) a slow growing commercially important herbal beverage with naturally high flavonoid concentrations, displayed decreased nodule activity and quantities of N fixed in different plant organs and whole plants with increased UV-B. This study's findings conclude negligible impacts of ozone depletion on nitrogen fixation and soil fertility in most traditional African farming systems, these limited to occasional inhibition of nodule induction in some crops. (author)

  14. Fluorometric titration approach for calibration of quantity of binding site of purified monoclonal antibody recognizing epitope/hapten nonfluorescent at 340 nm.

    Science.gov (United States)

    Yang, Xiaolan; Hu, Xiaolei; Xu, Bangtian; Wang, Xin; Qin, Jialin; He, Chenxiong; Xie, Yanling; Li, Yuanli; Liu, Lin; Liao, Fei

    2014-06-17

    A fluorometric titration approach was proposed for the calibration of the quantity of monoclonal antibody (mcAb) via the quench of fluorescence of tryptophan residues. It applied to purified mcAbs recognizing tryptophan-deficient epitopes, haptens nonfluorescent at 340 nm under the excitation at 280 nm, or fluorescent haptens bearing excitation valleys nearby 280 nm and excitation peaks nearby 340 nm to serve as Förster-resonance-energy-transfer (FRET) acceptors of tryptophan. Titration probes were epitopes/haptens themselves or conjugates of nonfluorescent haptens or tryptophan-deficient epitopes with FRET acceptors of tryptophan. Under the excitation at 280 nm, titration curves were recorded as fluorescence specific for the FRET acceptors or for mcAbs at 340 nm. To quantify the binding site of a mcAb, a universal model considering both static and dynamic quench by either type of probes was proposed for fitting to the titration curve. This was easy for fitting to fluorescence specific for the FRET acceptors but encountered nonconvergence for fitting to fluorescence of mcAbs at 340 nm. As a solution, (a) the maximum of the absolute values of first-order derivatives of a titration curve as fluorescence at 340 nm was estimated from the best-fit model for a probe level of zero, and (b) molar quantity of the binding site of the mcAb was estimated via consecutive fitting to the same titration curve by utilizing such a maximum as an approximate of the slope for linear response of fluorescence at 340 nm to quantities of the mcAb. This fluorometric titration approach was proved effective with one mcAb for six-histidine and another for penicillin G.

  15. 29 CFR 99.315 - Audit findings follow-up.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Audit findings follow-up. 99.315 Section 99.315 Labor Office... § 99.315 Audit findings follow-up. (a) General. The auditee is responsible for follow-up and corrective... include the reference numbers the auditor assigns to audit findings under § 99.510(c). Since the summary...

  16. Photosensitivity of the Er/Yb-Codoped Schott IOG1 Phosphate Glass Using 248 nm, Femtosecond, and Picosecond Laser Radiation

    International Nuclear Information System (INIS)

    Pissadakis, S.; Michelakaki, I.

    2009-01-01

    The effect of 248 nm laser radiation, with pulse duration of 5 picoseconds, 500 femtosecond, and 120 femtosecond, on the optical properties and the Knoop hardness of a commercial Er/Yb-codoped phosphate glass is presented here. Refractive index changes of the order of few parts of 10-4 are correlated with optical absorption centers induced in the glass volume, using Kramers-Kroning relationship. Accordingly, substantially lower refractive index changes are measured in volume Bragg gratings inscribed in the glass, indicating that, in addition to the optical density changes, volume dilation changes of negative sign may also be associated with the 248 nm ultrafast irradiation. The Knoop hardness experimental results reveal that the glass matrix undergoes an observable initial hardening and then a reversing softening and volume dilation process for modest accumulated energy doses, where the Knoop hardness follows a nonmonotonic trend. Comparative results on the Knoop hardness trend are also presented for the case of 193 nm excimer laser radiation. The above findings denote that the positive or negative evolution of refractive index changes induced by the 248 0nm ultrafast radiation in the glass is dominated by the counteraction of the color center formation and the volume modification effects.

  17. First Results of Using a UVTron Flame Sensor to Detect Alpha-Induced Air Fluorescence in the UVC Wavelength Range

    Directory of Open Access Journals (Sweden)

    Anita J. Crompton

    2017-11-01

    Full Text Available In this work, a robust stand-off alpha detection method using the secondary effects of alpha radiation has been sought. Alpha particles ionise the surrounding atmosphere as they travel. Fluorescence photons produced as a consequence of this can be used to detect the source of the alpha emissions. This paper details experiments carried out to detect this fluorescence, with the focus on photons in the ultraviolet C (UVC wavelength range (180–280 nm. A detector, UVTron R9533 (Hamamatsu, 325-6, Sunayama-cho, Naka-ku, Hamamatsu City, Shizuoka Pref., 430-8587, Japan, designed to detect the UVC emissions from flames for fire alarm purposes, was tested in various gas atmospheres with a 210Po alpha source to determine if this could provide an avenue for stand-off alpha detection. The results of the experiments show that this detector is capable of detecting alpha-induced air fluorescence in normal indoor lighting conditions, as the interference from daylight and artificial lighting is less influential on this detection system which operates below the UVA and UVB wavelength ranges (280315 nm and 315–380 nm respectively. Assuming a standard 1 r 2 drop off in signal, the limit of detection in this configuration can be calculated to be approximately 240 mm, well beyond the range of alpha-particles in air, which indicates that this approach could have potential for stand-off alpha detection. The gas atmospheres tested produced an increase in the detector count, with xenon having the greatest effect with a measured 52% increase in the detector response in comparison to the detector response in an air atmosphere. This type of alpha detection system could be operated at a distance, where it would potentially provide a more cost effective, safer, and faster solution in comparison with traditional alpha detection methods to detect and characterise alpha contamination in nuclear decommissioning and security applications.

  18. 21 CFR 137.280 - Bolted yellow corn meal.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Bolted yellow corn meal. 137.280 Section 137.280... Flours and Related Products § 137.280 Bolted yellow corn meal. Bolted yellow corn meal conforms to the definition and standard of identity prescribed by § 137.255 for bolted white corn meal except that cleaned...

  19. Eye hazards of environmental lighting

    International Nuclear Information System (INIS)

    Sliney, D.H.

    1985-01-01

    In the 1950s and 1960s it became clear that the nuclear fireball and lasers could cause thermal retinal injury; at that time, the reference of Verhoeff, Bell, and Walker was often cited to argue that solar eclipse blindness (solar retinitis) was also a thermal retinal injury. It was not until 1975 that it became clear that a photochemical mechanism for retinal injury was possible for lengthy exposures in the primate or human eye. The potential for photochemical injury of the retina suggests the possibilities of delayed effects, and a considerable research effort has been underway over the last decade to study the implications for retinal degradation by intense light. The lens can undergo changes leading to cataract following exposure to ultraviolet radiation (UVR). Although acute UVR injury of the cornea (photokeratitis) has been recognized since the early part of this century, the link between UVR and cataract has long been a point of controversy. Today, most scientists studying optical radiation hazards conclude that UVR is a causative factor in some forms of cataract. Differences of opinion arise as to the exact wavelength range that is effective (i.e., UVA: 315-400 nm and/or UVB: 280-315 nm). Pitts and colleagues have shown that only a very narrow band of UVR wavelengths between 295 and 320 nm appear to be effective in causing acute cataract in experimental animals. Epidemiological studies of cataract incidence appear to show that UVR is a causative factor, despite the fact that at least one investigator had concluded that high ambient temperature was a more likely causative factor than UVR. This author has recently completed a study of UVR exposures in the outdoor environment that would support the epidemiologic studies of UVR induction of cataract

  20. The induction and repair of cyclobutane thymidine dimers in human skin

    International Nuclear Information System (INIS)

    Roza, L.; Erasmus Univ., Rotterdam; Vermeulen, W.; Schans, G.P. van der; Lohman, P.H.M.

    1987-01-01

    The most important detrimental effect of ultraviolet radiation (UV) on the living cell, so far known, is the induction of damage in the DNA. The major photoproducts induced in DNA by UV-C (200-280 nm) and UV-B (280-315 nm) are the cyclobutane-type pyrimidine dimers, which have been implicated in UV-induced mutagenesis and carcinogenesis. Dimer lesions in DNA of cells may be repaired in the dark by a multi-enzyme process (excision repair), or via a light dependent enzymatic reaction known as photoreactivation (phr) which is specific for pyrimidine dimers. Although phr has been found to occur in a wide range of organisms, studies on the presence of phr in mammalian cells have yielded conflicting results. To investigate repair of pyrimidine dimers in human skin cells irradiated in vivo, a specific and sensitive detection method was developed based on a monoclonal antibody directed against thymidine dimers. Application together with a fluorescent immunostaining permits the direct detection of thymidine dimers in human skin cells. The method is used in studies aimed at a better understanding of the role of these lesions in the process of carcinogenesis. A report is given on the isolation and characterization of the antibodies, and their application in a study on the induction of pyrimidine dimers in human skin and on photorepair in cultured cells. 10 refs.; 2 figs

  1. Responses of phylloplane yeasts to UV-B (290-320 nm) radiation: interspecific differences in sensitivity

    International Nuclear Information System (INIS)

    Gunasekera, T.S.; Paul, N.D.; Ayres, P.G.

    1997-01-01

    The sensitivity to UV-B (290–320 nm) radiation of common phylloplane yeasts from two contrasting UV-B environments was compared in the laboratory using mixtures of white light (PAR: 400–700 nm) and UV-B radiation from artificial lamp sources. Sporidiobolus salmonicolor, Rhodotorula mucilaginosa and Cryptococcus sp., the dominant yeasts on leaves of tea (Camellia sinensis), were isolated in Sri Lanka (SL), while Sporidiobolus sp. and Bullera alba, dominant on faba bean (Vicia faba), were isolated in the U.K. Dose responses were determined separately for each yeast. UV-B reduced colony forming units (due to cell mortality or inactivation) and colony size (due to reduced multiplication) of all yeasts. The LD 50 values and doses causing 50% reduction of cells per colony were higher for SL isolates than U.K. isolates. Results indicated that each yeast is somewhat vulnerable to UV-B doses representative of its natural habitat. The relative insensitivity of SL isolates was shown when SL and U.K. isolates were irradiated simultaneously with the same dose of UV-B. Of the two U.K. yeasts, B. alba was significantly more sensitive than Sporidiobolus sp. to UV-B. Except for R. mucilaginosa from SL, all yeasts demonstrated some photorepair in the presence of white light. White light provided relatively little protection for the U.K. isolate of Sporidiobolus sp. although it allowed increased colony size. The spectral responses of Sporidiobolus sp. (U.K.) and of B. alba (U.K.) were broadly similar. Wavelengths longer than 320 nm had no measurable effect on colony forming units. However, colony survival was significantly reduced at 310 nm and all shorter wavebands. No colonies were counted at 290 nm or below. (author)

  2. Luminescence of Ga2O3 Crystals Excited with a Runaway Electron Beam

    Science.gov (United States)

    Burachenko, A. G.; Beloplotov, D. V.; Prudaev, I. A.; Sorokin, D. A.; Tarasenko, V. F.; Tolbanov, O. P.

    2017-12-01

    The spectra and amplitude-time characteristics of the radiation of studied Sn and Fe-doped Ga2O3 crystals excited with a runaway electron beam and an excilamp with a wavelength of 222 nm were investigated. The main contribution to the luminescence of samples in the region of 280-900 nm under excitation with a beam was shown to be made by cathodoluminescence. In the Fe-doped crystal, a new cathodeand photoluminescence band was detected within a wavelength range of 650-850 nm. In the Sn-doped crystal, Vavilov-Cherenkov radiation was detected in the region of 280-300 nm using a monochromator and a photomultiplier.

  3. 24 CFR 35.315 - Risk assessment.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Risk assessment. 35.315 Section 35... Provided by a Federal Agency Other Than HUD § 35.315 Risk assessment. Each owner shall complete a risk assessment in accordance with 40 CFR 745.227(d). Each risk assessment shall be completed in accordance with...

  4. 13 CFR 315.16 - Adjustment proposal requirements.

    Science.gov (United States)

    2010-01-01

    .... 315.16 Section 315.16 Business Credit and Assistance ECONOMIC DEVELOPMENT ADMINISTRATION, DEPARTMENT... financial and other supporting documentation as EDA determines is necessary, based upon either: (1) An... generally consists of knowledge-based services such as market penetration studies, customized business...

  5. [Photodegradation of chromophoric dissolved organic matter from Jiulong River Estuary under natural solar radiation].

    Science.gov (United States)

    Guo, Wei-dong; Cheng, Yuan-yue

    2008-06-01

    Low salinity water sample collected from Jiulong River Estuary filtered using 0.2 microm Millipore filter was exposed to natural solar radiation from 10:00 to 16:00 each day during one week period in early and late May, 2005. Photodegradation of fluorescence and absorption properties of CDOM (chromophoric dissolved organic matter) was observed. The results showed that humic-like fluorescence (lambda Ex/lambda Em = 350/450 nm), tryptophan-like fluorescence (lambda Ex/lambda Em = 225/350 nm) and absorption coefficient of CDOM can be significantly photodegraded during short-term solar exposure in early summer. These photodegradation processes followed the first-order dynamic equation. The degradation half time of humic-like fluorescence, tryptophan-like fluorescence and a (280) were calculated as 3.5-5.1 d, 3.0-4.5 d and 6.3 d. The absorption loss spectra of CDOM indicated that the solar UV radiation was responsible for the photochemical degradation of CDOM. The loss of humic-like fluorescence (70%) was obviously higher than loss of a (280) (about 40%), suggesting that photobleaching ability of CDOM fluorophores were much stronger than CDOM chromophores. However, the correlation relationship between humic-like fluorescence and absorption coefficient are still kept. A250/A350 of CDOM increased till the end of radiation experiment compared with the control group, suggesting photodegradation may decrease the average molecular size of CDOM. These findings show that terrestrial CDOM can be transformed and removed by photochemical decomposition after transport into the sea, and photodegradation might be an important sink for terrestrial CDOM.

  6. On the history of phyto-photo UV science (not to be left in skoto toto and silence).

    Science.gov (United States)

    Björn, Lars Olof

    2015-08-01

    This review of the history of ultraviolet photobiology focuses on the effects of UV-B (280-315 nm) radiation on terrestrial plants. It describes the early history of ultraviolet photobiology, the discovery of DNA as a major ultraviolet target and the discovery of photoreactivation and photolyases, and the later identification of Photosystem II as another important target for damage to plants by UV-B radiation. Some experimental techniques are briefly outlined. The insight that the ozone layer was thinning spurred the interest in physiological and ecological effects of UV-B radiation and resulted in an exponential increase over time in the number of publications and citations until 1998, at which time it was realized by the research community that the Montreal Protocol regulating the pollution of the atmosphere with ozone depleting substances was effective. From then on, the publication and citation rate has continued to rise exponentially, but with an abrupt change to lower exponents. We have now entered a phase when more emphasis is put on the "positive" effects of UV-B radiation, and with more emphasis on regulation than on damage and inhibition. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  7. Null bactericidal effect of ultraviolet radiation emitted by LEDs.

    Directory of Open Access Journals (Sweden)

    Francisco Alcántara Muñoz

    2016-11-01

    Full Text Available This research has aimed to assess the bactericidal effect of ultraviolet light emitted by LEDS on the growth on Petri dishes of microorganisms whose legal limits in foods have been established. An electrically fed apparatus has been designed with precise timing and a camera to prevent light spillage, in which two ultraviolet radiation emission devices were connected by LED technology at different wavelengths: through an array of LEDS emitting at around 350nm, and a single specific emission LED at 280nm. 1000 cfu of E. Coli and S. aureus sown on PCA were used as prototypes of gram negative and positive bacteria, respectively, onto which ultraviolet light was radiated at different time intervals, by means of both devices, with the whole experiment being carried out in triplicate . In none of the three series of treatments at the two wavelengths were reductions in microbial growth observed. The series of sowings on PCA were done on unseeded plates in order to be able to discard the likelihood of subsequent recontamination.

  8. Photochemistry of acrylates at 222 nm

    International Nuclear Information System (INIS)

    Knolle, Wolfgang; Naumov, Sergej; Madani, Mohamed; Sonntag, Clemens von

    2005-01-01

    Excimer lamps as monochromatic UV sources with an intense short-wavelength emission (especially KrCl * , 222 nm) allow a photoinitiator-free initiation of the acrylate polymerisation. Laser photolysis (KrCl * excimer laser, pulse width 20 ns, up to 5 mJ per pulse) gives rise to similar transient spectra (λ max ∼ 280 nm) for all acrylates studied. As the rather unspecific spectra do not allow conclusions as to the main reaction channel, a product study has been performed by GC-MS following steady-state photolysis of acrylate solutions in acetonitrile, methanol and n-hexane. Somewhat unexpected, α-cleavage seems to be a main reaction channel, and quantum chemical calculations show that such a reaction can occur from either the excited singlet state or the unrelaxed triplet state, but not from the relaxed triplet state that is observed spectroscopically. A reaction scheme accounting for the observed products is presented

  9. 13 CFR 315.13 - Audit and examination.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Audit and examination. 315.13 Section 315.13 Business Credit and Assistance ECONOMIC DEVELOPMENT ADMINISTRATION, DEPARTMENT OF COMMERCE... books, documents, papers, and records of a Firm, TAAC or other recipient of Adjustment Assistance...

  10. Repair of near-UV (365nm or 313 nm) induced DNA strand breaks

    International Nuclear Information System (INIS)

    Miguel, A.G.

    1981-01-01

    The action of near-UV (365 nm or 313 nm) radiation in cellular inactivaton (biological measurements) and induction and repair of breaks (physical measurements) is studied in repair proficient strain and in pol A, rec A and uvr A deficient strains of Escherichia coli K-12. (M.A.C.) [pt

  11. 9 CFR 113.315 - Feline Rhinotracheitis Vaccine.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Feline Rhinotracheitis Vaccine. 113.315 Section 113.315 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT... Inspection Service and observed each day for 14 days post-challenge. The rectal temperature of each animal...

  12. 15 CFR 315.1 - Scope and purpose.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Scope and purpose. 315.1 Section 315.1 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) INTERNATIONAL... International Trade, Department of Commerce pursuant to Department of Commerce Organization Order 40-1...

  13. 37 CFR 1.315 - Delivery of patent.

    Science.gov (United States)

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Delivery of patent. 1.315 Section 1.315 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES National Processing Provisions Allowance and Issue of...

  14. Effects of ultraviolet-B radiation (UV-B) on growth and physiology of the dune grassland species Calamagrostis epigeios

    International Nuclear Information System (INIS)

    Tosserams, M.; Rozema, J.

    1995-01-01

    Seedlings of Calamagrostis epigeios were exposed to four levels of UV-B radiation (280-320 nm), simulating up to 44% reduction of stratospheric ozone concentration during summertime in The Netherlands, to determine the response of this plant species to UV-B irradiation. After six weeks of UV-B treatment, total biomass of all UV-B treated plants was higher, compared to plants that had received no UV-B radiation. The increase of biomass did not appear to be the result of a stimulation of net photosynthesis. Also, transpiration rate and water use efficiency were not altered by UV-B at any exposure level. Pigment analysis of leaf extracts showed no effect of enhanced UV-B radiation on chlorophyll content and accumulation of UV absorbing pigments. UV-B irradiance, however, did reduce the transmittance of visible light (400-700 nm) of intact attached leaves, suggesting a change in anatomical characteristics of the leaves. Additionally, the importance of including an ambient UV-B treatment in indoor experiments is discussed

  15. Radiation tolerance study of a commercial 65 nm CMOS technology for high energy physics applications

    Energy Technology Data Exchange (ETDEWEB)

    Ding, Lili, E-mail: lili03.ding@gmail.com [Department of Information Engineering, Padova University, Via Gradenigo 6/B, 35131 Padova (Italy); INFN, Padova, Via Marzolo 8, 35131 Padova (Italy); State Key Laboratory of Pulsed Radiation Simulation and Effect, Northwest Institute of Nuclear Technology, Xi' an (China); Gerardin, Simone [Department of Information Engineering, Padova University, Via Gradenigo 6/B, 35131 Padova (Italy); INFN, Padova, Via Marzolo 8, 35131 Padova (Italy); Bagatin, Marta [Department of Information Engineering, Padova University, Via Gradenigo 6/B, 35131 Padova (Italy); Bisello, Dario [Department of Physics and Astronomy, Padova University, Via Marzolo 8, 35131 Padova (Italy); INFN, Padova, Via Marzolo 8, 35131 Padova (Italy); Mattiazzo, Serena [Department of Physics and Astronomy, Padova University, Via Marzolo 8, 35131 Padova (Italy); Paccagnella, Alessandro [Department of Information Engineering, Padova University, Via Gradenigo 6/B, 35131 Padova (Italy); INFN, Padova, Via Marzolo 8, 35131 Padova (Italy)

    2016-09-21

    This paper reports the radiation tolerance study of a commercial 65 nm technology, which is a strong candidate for the Large Hadron Collider applications. After exposure to 3 MeV protons till 1 Grad dose, the 65 nm CMOS transistors, especially the pMOSFETs, showed severe long-term degradation mainly in the saturation drain currents. There were some differences between the degradation levels in the nMOSFETs and the pMOSFETs, which were likely attributed to the positive charges trapped in the gate spacers. After exposure to heavy ions till multiple strikes, the pMOSFETs did not show any sudden loss of drain currents, the degradations in the characteristics were negligible.

  16. Characterization of radiation effects in 65 nm digital circuits with the DRAD digital radiation test chip

    International Nuclear Information System (INIS)

    Casas, L.M. Jara; Ceresa, D.; Kulis, S.; Christiansen, J.; Francisco, R.; Miryala, S.; Gnani, D.

    2017-01-01

    A Digital RADiation (DRAD) test chip has been specifically designed to study the impact of Total Ionizing Dose (TID) (<1 Grad) and Single Event Upset (SEU) on digital logic gates in a 65 nm CMOS technology. Nine different versions of standard cell libraries are studied in this chip, basically differing in the device dimensions, V t flavor and layout of the device. Each library has eighteen test structures specifically designed to characterize delay degradation and power consumption of the standard cells. For SEU study, a dedicated test structure based on a shift register is designed for each library. TID results up to 500 Mrad are reported.

  17. UV sensitivity of planktonic net community production in ocean surface waters

    Science.gov (United States)

    Regaudie-de-Gioux, Aurore; Agustí, Susana; Duarte, Carlos M.

    2014-05-01

    The net plankton community metabolism of oceanic surface waters is particularly important as it more directly affects the partial pressure of CO2 in surface waters and thus the air-sea fluxes of CO2. Plankton communities in surface waters are exposed to high irradiance that includes significant ultraviolet blue (UVB, 280-315 nm) radiation. UVB radiation affects both photosynthetic and respiration rates, increase plankton mortality rates, and other metabolic and chemical processes. Here we test the sensitivity of net community production (NCP) to UVB of planktonic communities in surface waters across contrasting regions of the ocean. We observed here that UVB radiation affects net plankton community production at the ocean surface, imposing a shift in NCP by, on average, 50% relative to the values measured when excluding partly UVB. Our results show that under full solar radiation, the metabolic balance shows the prevalence of net heterotrophic community production. The demonstration of an important effect of UVB radiation on NCP in surface waters presented here is of particular relevance in relation to the increased UVB radiation derived from the erosion of the stratospheric ozone layer. Our results encourage design future research to further our understanding of UVB effects on the metabolic balance of plankton communities.

  18. Radiation induced processes in moss cells

    International Nuclear Information System (INIS)

    Doehren, R. v.

    1975-01-01

    The moss F.h. shows apical growth in the protonema cells which spread radially from the spor. Every apical daughter cell during the state of 'Caulonema' and just before in the state of 'Caulonema Primanen' initiates cell division as soon as more than twice the length of the mother cell is reached. All this allows to follow radiation effects in single cells conveniently. UV irradiation on the range of 254 nm and 280 nm delivered at different parts of the cell area delays cell division markedly may suppress it, and is able to stop the process of growing in relation to the delivered dose and to the irradiated area as well. In case of irradiation of the area next to where the membrane is just being formed - that is to say next to the phragmoplast - the new membrane will be wrongly oriented. In particular giant cells are occurring in the case of nucleus irradiation during early prophase. (orig./GSE) [de

  19. 26 CFR 1.280B-1 - Demolition of structures.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 3 2010-04-01 2010-04-01 false Demolition of structures. 1.280B-1 Section 1... (CONTINUED) INCOME TAXES Items Not Deductible § 1.280B-1 Demolition of structures. (a) In general. Section 280B provides that, in the case of the demolition of any structure, no deduction otherwise allowable...

  20. 46 CFR 280.4 - Standards governing payment of ODS.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Standards governing payment of ODS. 280.4 Section 280.4... Standards governing payment of ODS. (a) Full payment. Except to the extent otherwise provided in § 280.8, ODS shall be paid in full to the operator for vessel operations on the inbound and outbound legs of...

  1. Beneficial and Detrimental Effects of UV on Aquatic Organisms: Implications of Spectral Variation

    NARCIS (Netherlands)

    Williamson, C.E.; Neale, P.J.; Grad, G.; Lange, de H.J.; Hargreaves, B.R.

    2001-01-01

    Solar ultraviolet radiation (UVR) may have beneficial as well as detrimental effects on living systems. For example, UV-B radiation (280¿320 nm) is generally damaging, while UV-A radiation (320¿400 nm) may cause damage or stimulate beneficial photorepair of UV-B damage. The nature of both direct and

  2. Comparative analysis of the effect of the GaAlAs laser irradiation in 780 nm and 660 nm in the hypersensitive dentin

    International Nuclear Information System (INIS)

    Yuan, Sun Chien

    2003-01-01

    This study was to evaluate and compare the effects of the low intensity in laser radiation among GaAlAs 780 nm and GaAlAs 660 nm. The main proposal is to verify if there is any difference of the effects or results in low intensity laser application treatment of hypersensitive dentin, keeping the same parameters, only differing in wavelength. The samples were distributed in two groups. Group A 90 cases, treated with GaAlAs 780 nm and group B irradiated with GaAlAs 660 nm with a total of 76 cases analyzed. The results of application with GaAlAs 660 nm and GaAlAs 780 nm do not differ statistically. Which means using any one of the irradiation gives the same results. However can be noted that the response of reduction of hypersensitivity is faster with the radiation of GaAlAs 780 nm, but the results after three applications is the same for both types of radiation. (author)

  3. 38 CFR 3.315 - Basic eligibility determinations; dependents, loans, education.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Basic eligibility determinations; dependents, loans, education. 3.315 Section 3.315 Pensions, Bonuses, and Veterans' Relief... Ratings and Evaluations; Service Connection § 3.315 Basic eligibility determinations; dependents, loans...

  4. Partial inhibition of in vitro pollen germination by simulated solar ultraviolet-B radiation

    International Nuclear Information System (INIS)

    Flint, S.D.; Caldwell, M.M.

    1984-01-01

    Pollen from four temperate-latitude taxa were treated with UV radiation in a portion of the UV-B (280-320 nm) waveband during in vitro germination. Inhibition of germination was noted in this pollen compared to samples treated identically except for the exclusion of the UV-B portion of the spectrum. Levels similar to maximum solar UV-B found in temperate-latitude areas failed to inhibit pollen germination significantly, while levels similar to maximum solar UV-B found in equatorial alpine locations caused partial inhibition of germination in three of the four taxa examined

  5. Comparison of Mg-based multilayers for solar He II radiation at 30.4 nm wavelength

    Energy Technology Data Exchange (ETDEWEB)

    Zhu Jingtao; Zhou Sika; Li Haochuan; Huang Qiushi; Wang Zhanshan; Le Guen, Karine; Hu, Min-Hui; Andre, Jean-Michel; Jonnard, Philippe

    2010-07-10

    Mg-based multilayers, including SiC/Mg, Co/Mg, B4C/Mg, and Si/Mg, are investigated for solar imaging and a He II calibration lamp at a 30.4 nm wavelength. These multilayers were fabricated by a magnetron sputtering method and characterized by x-ray reflection. The reflectivities of these multilayers were measured by synchrotron radiation. Near-normal-incidence reflectivities of Co/Mg and SiC/Mg multilayer mirrors are as high as 40.3% and 44.6%, respectively, while those of B4C/Mg and Si/Mg mirrors are too low for application. The measured results suggest that SiC/Mg, Co/Mg multilayers are promising for a 30.4 nm wavelength.

  6. Effect of variable doses of ultraviolet radiation (253.7 nm) on thermoluminescence NaCl:Ca(T) material

    International Nuclear Information System (INIS)

    Nehate, A.K.; Joshi, T.R.; Kathuria, S.P.; Joshi, R.V.

    1986-01-01

    This paper studies the thermoluminescence (TL) glow curves of NaCl:Ca(T) phosphors to various doses of 253.7-nm ultraviolet (UV) radiation at room temperature. TLD grade NaCl:Ca(T) material was obtained by crystallization from solution and was subsequently annealed at 750 degrees C for 2 h, followed by sudden quenching. We undertook measurement of the effect of variable UV radiation doses (10(2) to 10(6) J m-2) on the TL behaviour of NaCl:Ca(T) phosphors. It was observed that the phosphor exhibits a dominant peak around 167 degrees C along with a weak peak at lower temperature. The high-temperature peak (Peak II) is found to grow linearly with the increase in UV dose in the range of 10(2) to 10(6) J m-2. Since the nature of the glow curves under the influence of different doses remains more or less identical, it is believed that the phosphor does not undergo radiation damage and displays high intrinsic TL around Peak II. Examination of the system for fundamental dosimetry requirements shows that it can be used in dosimetry work at 253.7 nm

  7. Toxic effects of ultraviolet radiation on the skin

    International Nuclear Information System (INIS)

    Matsumura, Yasuhiro; Ananthaswamy, Honnavara N.

    2004-01-01

    Ultraviolet (UV) irradiation present in sunlight is an environmental human carcinogen. The toxic effects of UV from natural sunlight and therapeutic artificial lamps are a major concern for human health. The major acute effects of UV irradiation on normal human skin comprise sunburn inflammation (erythema), tanning, and local or systemic immunosuppression. At the molecular level, UV irradiation causes DNA damage such as cyclobutane pyrimidine dimers and (6-4) photoproducts, which are usually repaired by nucleotide excision repair (NER). Chronic exposure to UV irradiation leads to photoaging, immunosuppression, and ultimately photocarcinogenesis. Photocarcinogenesis involves the accumulation of genetic changes, as well as immune system modulation, and ultimately leads to the development of skin cancers. In the clinic, artificial lamps emitting UVB (280-320 nm) and UVA (320-400 nm) radiation in combination with chemical drugs are used in the therapy of many skin diseases including psoriasis and vitiligo. Although such therapy is beneficial, it is accompanied with undesirable side effects. Thus, UV radiation is like two sides of the same coin--on one side, it has detrimental effects, and on the other side, it has beneficial effects

  8. 33 CFR 159.315 - Sewage and graywater discharge record book.

    Science.gov (United States)

    2010-07-01

    ... record book. 159.315 Section 159.315 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND... by Cruise Vessel Operations § 159.315 Sewage and graywater discharge record book. (a) While operating... and Graywater Discharge Record Book with the vessel's name and official number listed on the front...

  9. Different (direct and indirect) mechanisms for the induction of DNA-protein crosslinks in human cells by far- and near-ultraviolet radiations (290 and 405 nm)

    International Nuclear Information System (INIS)

    Peak, M.J.; Peak, J.G.; Jones, C.A.

    1985-01-01

    Apparent DNA-protein crosslinking induced by monochromatic 290 and 405 nm radiations was measured in cultured human P3 teratocarcinoma cells with DNA alkaline elution techniques. The rates of the induction of crosslinks by 290 nm radiation were the same when the cells were irradiated either aerobically or anaerobically or when the cells were in an H 2 O or D 2 O aqueous environment. With 405 nm radiation, anaerobic irradiation reduced the induction of the crosslinks (dose modifying factor is about 0.2), and about twice as many crosslinks were observed when the cells were irradiated in an environment of D 2 O rather than H 2 O. The results are consistent with the hypothesis that far-UV radiation induces DNA-protein crosslinks by a direct mechanism, whereas near-UV radiation induces crosslinks via indirect photodynamic photosensitizations in which unidentified cellular endogenous photosensitizers and reactive species of oxygen are used. (author)

  10. Forecasting noise and radiation hardness of CMOS front-end electronics beyond the 100 nm frontier

    International Nuclear Information System (INIS)

    Re, V.; Gaioni, L.; Manghisoni, M.; Ratti, L.; Traversi, G.

    2010-01-01

    The progress of industrial microelectronic technologies has already overtaken the 130 nm CMOS generation that is currently the focus of IC designers for new front-end chips in LHC upgrades and other detector applications. In a broader time span, sub-100 nm CMOS processes may become appealing for the design of very compact front-end systems with advanced integrated functionalities. This is especially true in the case of pixel detectors, both for monolithic devices (MAPS) and for hybrid implementations where a high resistivity sensor is connected to a CMOS readout chip. Technologies beyond the 100 nm frontier have peculiar features, such as the evolution of the device gate material to reduce tunneling currents through the thin dielectric. These new physical device parameters may impact on functional properties such as noise and radiation hardness. On the basis of experimental data relevant to commercial devices, this work studies potential advantages and challenges associated to the design of low-noise and rad-hard analog circuits in these aggressively scaled technologies.

  11. PAR and UVBR effects on photosynthesis, viability, growth and DNA in different life stages of two coexisting Gigartinales : implications for recruitment and zonation pattern

    NARCIS (Netherlands)

    Roleda, MY; van de Poll, WH; Hanelt, D; Wiencke, C

    2004-01-01

    The effects that ultraviolet radiation (UVR, 280 to 400 nm) and photosynthetically active radiation (PAR, 400 to 700 nm) had on early life stages of Mastocarpus stellatus and Chondrus crispus were studied to determine if differences in UVR tolerance could influence their recruitment success on the

  12. Development of Radiation-hard Bandgap Reference and Temperature Sensor in CMOS 130 nm Technology

    CERN Document Server

    Kuczynska, Marika; Bugiel, Szymon; Firlej, Miroslaw; Fiutowski, Tomasz; Idzik, Marek; Michelis, Stefano; Moron, Jakub; Przyborowski, Dominik; Swientek, Krzysztof

    2015-01-01

    A stable reference voltage (or current) source is a standard component of today's microelectronics systems. In particle physics experiments such reference is needed in spite of harsh ionizing radiation conditions, i.e. doses exceeding 100 Mrads and fluences above 1e15 n/cm2. After such radiation load a bandgap reference using standard p-n junction of bipolar transistor does not work properly. Instead of using standard p-n junctions, two enclosed layout transistor (ELTMOS) structures are used to create radiation-hard diodes: the ELT bulk diode and the diode obtained using the ELTMOS as dynamic threshold transistor (DTMOS). In this paper we have described several sub-1V references based on ELTMOS bulk diode and DTMOS based diode, using CMOS 130 nm process. Voltage references the structures with additional PTAT (Proportional To Absolute Temperature) output for temperature measurements were also designed. We present and compare post-layout simulations of the developed bandgap references and temperature sensors, w...

  13. 9 CFR 93.315 - Import permit and declaration for horses.

    Science.gov (United States)

    2010-01-01

    ... horses. 93.315 Section 93.315 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE...; REQUIREMENTS FOR MEANS OF CONVEYANCE AND SHIPPING CONTAINERS Horses Canada 16 § 93.315 Import permit and declaration for horses. For all horses offered for importation from Canada, the importer or his or her agent...

  14. 29 CFR 1952.315 - Where the plan may be inspected.

    Science.gov (United States)

    2010-07-01

    ... and copied during normal business hours at the following locations: Office of State Programs... 29 Labor 9 2010-07-01 2010-07-01 false Where the plan may be inspected. 1952.315 Section 1952.315..., DEPARTMENT OF LABOR (CONTINUED) APPROVED STATE PLANS FOR ENFORCEMENT OF STATE STANDARDS Hawaii § 1952.315...

  15. 16 CFR 315.7 - Content of advertisements and other representations.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Content of advertisements and other representations. 315.7 Section 315.7 Commercial Practices FEDERAL TRADE COMMISSION REGULATIONS UNDER SPECIFIC ACTS OF CONGRESS CONTACT LENS RULE § 315.7 Content of advertisements and other representations. Any person who engages in the manufacture,...

  16. 46 CFR 280.8 - Certain ODS agreement provisions not affected.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Certain ODS agreement provisions not affected. 280.8 Section 280.8 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION REGULATIONS AFFECTING... LINER OPERATORS § 280.8 Certain ODS agreement provisions not affected. The provisions of this part are...

  17. Photoreactivation of cells and phages inactivated by UV of ecological wave-lengths

    International Nuclear Information System (INIS)

    Samojlova, K.A.; Yanovska, Eh.; Vizdalova, M.; Ceskoslovenska Akademie Ved, Brno. Biofysikalni Ustav)

    1979-01-01

    It has been found that the photoreactivity of infusoria Paramecium caudatum and bacteria Escherichia coli is high and practically similar if they are irradiated with short-wave (254 nm) and mean-wave (300-315 nm) UV radiation. The cells damaged with long-wave (315-400 nm) UV rays are not photoactivated. The latter is caused by the appearance of nonphotoreactivated damages since the phages jrradiated with the same UV rays are reactivated extremely weakly in the intact cells of bacteria (phage T7) or are not reactivated at all (phage lambdasub(c1 857))

  18. 21 CFR 172.315 - Nicotinamide-ascorbic acid complex.

    Science.gov (United States)

    2010-04-01

    ... 172.315 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION Special Dietary and Nutritional Additives § 172.315 Nicotinamide-ascorbic acid complex...

  19. 13 CFR 315.10 - Loss of certification benefits.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Loss of certification benefits. 315.10 Section 315.10 Business Credit and Assistance ECONOMIC DEVELOPMENT ADMINISTRATION, DEPARTMENT... expiration; (b) Failure to submit documentation necessary to start implementation or modify its request for...

  20. Optical Design of Porous ZnO/TiO2 Films for Highly Transparent Glasses with Broadband Ultraviolet Protection

    Directory of Open Access Journals (Sweden)

    Han Sung Song

    2017-01-01

    Full Text Available We present a design of a bilayer porous film structure on a glass substrate for the highly efficient ultraviolet (UV protection with high visible-light transparency. To effectively block UVB (280315nm and UVA (315–400 nm, titanium dioxide (TiO2 and zinc oxide (ZnO are used as absorbing layers having the appropriate coverages in different UV ranges with extinction coefficients, respectively. We show the process of refractive index (RI matching by controlling porosity (Pr. Effective RIs of porous media with TiO2 and ZnO were calculated based on volume averaging theory. Transmittances of the designed films with different effective RIs were calculated using rigorous coupled-wave analysis method. Using admittance loci method, the film thickness was optimized in center wavelengths from 450 to 550 nm. The results show that the optimal design provides high UV shielding performance at both UVA and UVB with high transparency in the visible range. We also analyze electrical field distributions in each layer and angle dependency with 3D HSV color map.

  1. Fotoprotección antioxidante no-enzimática contra el potencial daño inducido por UVBR en una diatomea antártica (Thalassiosira sp. Non-enzymatic antioxidant photoprotection against potential UVBR-induced damage in an Antarctic diatom (Thalassiosira sp.

    Directory of Open Access Journals (Sweden)

    Marcelo Hernando

    2011-11-01

    Full Text Available In January 1999, unialgal cultures of the diatom Thalassiosira sp., solate from natural phyto-plankton assemblages from Potter Cove, Antarctica, were exposed to solar ultraviolet radiation (UVR, 280400 nm in order to study the long-term acclimation of this species. Ultraviolet radiation B (UVBR, 280-315 nm inhibited the growth rate during the first and second days of exposure. No UVBR inhibition was observed on the third day. The initial content of α-tocopherol (13 pmol (10(4 cell-1 showed a marked decrease during the exponential growth phase (4 pmol (10(4 cell-1 by day 3. The initial content of β-carotene (3 pmol (10(4 cell-1 did not show significant differences over time in cells exposed to UVBR. Two mycosporine-like amino acids (MAAs were identified: porphyra-334 and shinorine. Cellular concentrations of MAAs increased significantly on days 2 and 3, and exposure of the algae to UVBR significantly enhanced this value. The relative importance of MAAs concentration was significant (P Durante enero 1999, cultivos unialgales de una diatomea Thalassiosira sp., aislada de poblaciones fitoplanctónicas naturales de Caleta Carlos Potter, Antártida, fueron expuestos a radiación solar ultravioleta (UVR, 280-400 nm con el objetivo de estudiar su aclimatación a largo plazo. La radiación ultravioleta B (UVBR, 280-315 nm inhibió la tasa de crecimiento durante el primer y segundo día de exposición. No se observó inhibición por UVBR durante el tercer día. El contenido inicial de α-tocopherol (13 pmol (10(4 cel-1 mostró una marcada disminución durante la fase de crecimiento exponencial (4 pmol (10(4 cel-1 al día 3. El contenido inicial de β-caroteno (3 pmol (10(4 cel-1 no mostró diferencias significativas entre días en células expuestas a UVBR. Se identificaron dos aminoácidos parecidos a micosporina (MAAs, porfira-334 y shinorina. Las concentraciones celulares de MAAs mostraron aumentos significativos en los días 2 y 3, que resultaron

  2. 20 CFR 628.315 - Education coordination and grants.

    Science.gov (United States)

    2010-04-01

    ... lifelong learning opportunities and services of demonstrated effectiveness, including basic education and... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Education coordination and grants. 628.315... UNDER TITLE II OF THE JOB TRAINING PARTNERSHIP ACT State Programs § 628.315 Education coordination and...

  3. 31 CFR 315.84 - Payment to certain institutions.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Payment to certain institutions. 315.84 Section 315.84 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued..., for example, “Shriners' Hospital for Crippled Children, St. Louis, MO, by William A. Smith...

  4. Gold-coated copper cone detector as a new standard detector for F2 laser radiation at 157 nm

    International Nuclear Information System (INIS)

    Kueck, Stefan; Brandt, Friedhelm; Taddeo, Mario

    2005-01-01

    A new standard detector for high-accuracy measurements of F2 laser radiation at 157 nm is presented. This gold-coated copper cone detector permits the measurement of average powers up to 2 W with an uncertainty of ∼1%. To the best of our knowledge, this is the first highly accurate standard detector for F2 laser radiation for this power level. It is fully characterized according to Guide to the Expression of Uncertainty in Measurement of the International Organization for Standardization and is connected to the calibration chain for laser radiation established by the German National Metrology Institute

  5. 31 CFR 315.56 - General instructions and liability.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false General instructions and liability. 315.56 Section 315.56 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued... and, where one is available, a corporate stamp or issuing or paying agent's stamp. (b) Liability. The...

  6. 31 CFR 315.7 - Authorized forms of registration.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Authorized forms of registration. 315.7 Section 315.7 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued...' Hospital for Crippled Children, St. Louis, MO, 12-3456789. St. Mary's Roman Catholic Church, Albany, NY, 12...

  7. Generation of 99-mW continuous-wave 285-nm radiation for magneto-optical trapping of Mg atoms

    DEFF Research Database (Denmark)

    Madsen, Dorte Nørgaard; Yu, Ping; Balslev, Søren

    2002-01-01

    We have developed a tunable intense narrow-band 285 nm light source based on frequency doubling of 570 nm light in BBO. At input powers of 840 mW (including 130 mW used for locking purposes) we generate 99 mW UV radiation with an intensity profile suitable for laser-cooling experiments. The light...... is used for laser cooling of neutral magnesium atoms in a magneto-optical trap (MOT). We capture about 5 x 10(6) atoms directly from a thermal beam and find that the major loss mechanism of the magnesium MOT is a near-resonant two-photon ionization process....

  8. 31 CFR 315.55 - Individuals authorized to certify.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Individuals authorized to certify. 315.55 Section 315.55 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued... authenticated by a legible imprint either of a corporate stamp of the institution or of the issuing or paying...

  9. 14 CFR 152.315 - Reporting on accrual basis.

    Science.gov (United States)

    2010-01-01

    ...) AIRPORTS AIRPORT AID PROGRAM Accounting and Reporting Requirements § 152.315 Reporting on accrual basis. (a... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Reporting on accrual basis. 152.315 Section... financial reports on an accrual basis. (b) If records are not maintained on an accrual basis by a sponsor or...

  10. 31 CFR 540.315 - Uranium-235 (U235).

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Uranium-235 (U235). 540.315 Section... FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY HIGHLY ENRICHED URANIUM (HEU) AGREEMENT ASSETS CONTROL REGULATIONS General Definitions § 540.315 Uranium-235 (U235). The term uranium-235 or U235 means the fissile...

  11. Nitrogen capillary plasma as a source of intense monochromatic radiation at 2.88 nm

    Energy Technology Data Exchange (ETDEWEB)

    Vrba, P., E-mail: vrbovmir@fbmi.cvut.cz [Institute of Plasma Physics, Academy of Sciences, Za Slovankou 3, Prague 8 (Czech Republic); Vrbova, M. [Faculty of Biomedical Engineering, CTU in Prague, Sitna 3105, Kladno 2 (Czech Republic); Zakharov, S.V. [EPPRA sas, Villebon/Yvette (France); Zakharov, V.S. [EPPRA sas, Villebon/Yvette (France); KIAM RAS, Moscow (Russian Federation); Jancarek, A.; Nevrkla, M. [Faculty of Nuclear Science and Physical Engineering, CTU in Prague, Brehova 7, Prague 1 (Czech Republic)

    2014-10-15

    Highlights: • Pinching capillary discharge is studied as a source of monochromatic SXR. • Modeling of the laboratory device was performed by RMHD Z* code. • Results of computer and laboratory experiments are presented. - Abstract: Capillary discharge plasma related to our laboratory device is modeled and the results are compared with experimental data. Time dependences of selected plasma quantities (e.g. plasma mass density, electron temperature and density and emission intensities) evaluated by 2D Radiation-Magneto-Hydro-Dynamic code Z* describe plasma evolution. The highest output pulse energy at 2.88 nm wavelength is achieved for nitrogen filling pressure ∼100 Pa. The estimated output energy of monochromatic radiation 5.5 mJ sr{sup −1} (∼10{sup 14} photons sr{sup −1}) corresponds properly to observe experimental value ∼3 × 10{sup 13} photons sr{sup −1}. Ray tracing inspection along the capillary axis proves an influence of radiation self-absorption for the investigated wavelength. The spectra, evaluated using the FLY code, agree to the measured ones.

  12. 20 CFR 404.280 - Recomputations.

    Science.gov (United States)

    2010-04-01

    ...- ) Computing Primary Insurance Amounts Recomputing Your Primary Insurance Amount § 404.280 Recomputations. At...) Methods of recomputing (§§ 404.283 and 404.284), (d) Automatic recomputations (§ 404.285), (e) Requesting...

  13. Picosecond laser texturization of mc-silicon for photovoltaics: A comparison between 1064 nm, 532 nm and 355 nm radiation wavelengths

    Energy Technology Data Exchange (ETDEWEB)

    Binetti, Simona [Department of Materials Science and Milano-Bicocca Solar Energy Research Center (MIB-SOLAR), University of Milano-Bicocca, Via Cozzi 55, 20125 Milano (Italy); Le Donne, Alessia, E-mail: alessia.ledonne@mater.unimib.it [Department of Materials Science and Milano-Bicocca Solar Energy Research Center (MIB-SOLAR), University of Milano-Bicocca, Via Cozzi 55, 20125 Milano (Italy); Rolfi, Andrea [Department of Materials Science and Milano-Bicocca Solar Energy Research Center (MIB-SOLAR), University of Milano-Bicocca, Via Cozzi 55, 20125 Milano (Italy); Jäggi, Beat; Neuenschwander, Beat [Bern University of Applied Sciences, Engineering and Information Technology, Institute for Applied Laser, Photonics and Surface Technologies ALPS, Pestalozzistrasse 20, CH-3400 Burgdorf (Switzerland); Busto, Chiara [ENI Spa, Via Giacomo Fauser, 4, 28100 Novara (Italy); Frigeri, Cesare [CNR-IMEM Institute, Parco Area Delle Scienze 37/A, Fontanini, 43010 Parma (Italy); Scorticati, Davide; Longoni, Luca; Pellegrino, Sergio [Laserpoint Srl, Via Della Burrona 51, 20090 Vimodrone, Milano (Italy)

    2016-05-15

    Highlights: • Self-organized surface structures were produced by picosecond laser pulses on mc-Si. • Three laser wavelengths were used which effectively reduce Si reflectivity up to 8%. • The subsurface damage induced by the three lasers was studied in detail. • μ-Raman, PL and TEM proved that UV laser provides the lowest subsurface damage. • UV laser induced damage is located above the depletion region of the p–n junction. - Abstract: Self-organized surface structures were produced by picosecond laser pulses on multi-crystalline silicon for photovoltaic applications. Three different laser wavelengths were employed (i.e. 1064 nm, 532 nm and 355 nm) and the resulting morphologies were observed to effectively reduce the reflectivity of the samples after laser irradiation. Besides, a comparative study of the laser induced subsurface damage generated by the three different wavelengths was performed by confocal micro-Raman, photoluminescence and transmission electron microscopy. The results of both the structural and optical characterization showed that the mc-Si texturing performed with the laser at 355 nm provides surface reflectivity between 11% and 8% over the spectral range from 400 nm to 1 μm, while inducing the lowest subsurface damage, located above the depletion region of the p–n junction.

  14. Absorbance detector for high performance liquid chromatography based on a deep-UV light-emitting diode at 235nm.

    Science.gov (United States)

    da Silveira Petruci, João Flavio; Liebetanz, Michael G; Cardoso, Arnaldo Alves; Hauser, Peter C

    2017-08-25

    In this communication, we describe a flow-through optical absorption detector for HPLC using for the first time a deep-UV light-emitting diode with an emission band at 235nm as light source. The detector is also comprised of a UV-sensitive photodiode positioned to enable measurement of radiation through a flow-through cuvette with round aperture of 1mm diameter and optical path length of 10mm, and a second one positioned as reference photodiode; a beam splitter and a power supply. The absorbance was measured and related to the analyte concentration by emulating the Lambert-Beer law with a log-ratio amplifier circuitry. This detector showed noise levels of 0.30mAU, which is comparable with our previous LED-based detectors employing LEDs at 280 and 255nm. The detector was coupled to a HPLC system and successfully evaluated for the determination of the anti-diabetic drugs pioglitazone and glimepiride in an isocratic separation and the benzodiazepines flurazepam, oxazepam and clobazam in a gradient elution. Good linearities (r>0.99), a precision better than 0.85% and limits of detection at sub-ppm levels were achieved. Copyright © 2017 Elsevier B.V. All rights reserved.

  15. 40 CFR 280.200 - Definitions.

    Science.gov (United States)

    2010-07-01

    ... the production of crude oil or other forms of petroleum (as defined in § 280.12) as well as the..., distillation, separation, conversion, upgrading, and finishing of refined petroleum or petroleum products. (3...

  16. A Monolithic Active Pixel Sensor for ionizing radiation using a 180 nm HV-SOI process

    Energy Technology Data Exchange (ETDEWEB)

    Hemperek, Tomasz, E-mail: hemperek@uni-bonn.de; Kishishita, Tetsuichi; Krüger, Hans; Wermes, Norbert

    2015-10-01

    An improved SOI-MAPS (Silicon On Insulator Monolithic Active Pixel Sensor) for ionizing radiation based on thick-film High Voltage SOI technology (HV-SOI) has been developed. Similar to existing Fully Depleted SOI-based (FD-SOI) MAPS, a buried silicon oxide inter-dielectric (BOX) layer is used to separate the CMOS electronics from the handle wafer which is used as a depleted charge collection layer. FD-SOI MAPS suffers from radiation damage such as transistor threshold voltage shifts due to charge traps in the oxide layers and charge states created at the silicon oxide boundaries (back gate effect). The X-FAB 180-nm HV-SOI technology offers an additional isolation by deep non-depleted implant between the BOX layer and the active circuitry which mitigates this problem. Therefore we see in this technology a high potential to implement radiation-tolerant MAPS with fast charge collection property. The design and measurement results from a first prototype are presented including charge collection in neutron irradiated samples.

  17. 15 CFR 315.4 - Determination by the Under Secretary.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Determination by the Under Secretary. 315.4 Section 315.4 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) INTERNATIONAL TRADE ADMINISTRATION, DEPARTMENT OF COMMERCE MISCELLANEOUS REGULATIONS...

  18. 46 CFR 280.3 - Standards governing award of an ODS agreement.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Standards governing award of an ODS agreement. 280.3 Section 280.3 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION REGULATIONS AFFECTING... LINER OPERATORS § 280.3 Standards governing award of an ODS agreement. No ODS agreement, including any...

  19. Biostimulation effects on wheat seeds (Triticum Aestivum L) caused by low level red laser radiation with λ = 660 nm

    International Nuclear Information System (INIS)

    Hernandez, M.; Michtchenko, A.

    2009-01-01

    The principal objective is to study the biostimulation effects caused by a semiconductor low level laser radiation with ? = 660 nm on wheat seeds (Triticum Aestivum L). Seeds were treated before sowing with this laser light source. An increase in the growth of the stem of 12% with respect to control seeds was registered for seeds radiated by an intensity of 15mW/cm 2 and an irradiation time of 60 seconds. (Author)

  20. Ozone and ultraviolet-B irradiances: experimental determination of the radiation amplification factor

    International Nuclear Information System (INIS)

    Blumthaler, M.; Salzgeber, M.; Ambach, W.

    1995-01-01

    During the period 1981-1993, measurements of solar UV irradiances were made at the High-Alpine Research Station Jungfraujoch (Switzerland, 3576 m a.s.l.) to determine the radiation amplification factor (RAF) for the Robertson-Berger sunburn meter and for the narrow-band wavelength ranges of the Eppley filter spectrometer. The Robertson-Berger sunburn meter model 500 showed a RAF of 1.07 ± 0.15 at solar elevations between 20 o and 60 o . The RAF for human erythema is 1.1 in comparison. Therefore the Robertson-Berger sunburn meter is suitable to measure the influence of total atmospheric ozone variations on the effective erythemal irradiance. In the narrow-band wavelength ranges of the Eppley filter spectrometer the RAF increases greatly at shorter wavelengths with RAF of 1.06, 1.40 and 2.35 for the optical centers 315.1 nm, 311.1 nm and 305.2 nm, evaluated at 30 o solar elevation. In order to minimize perturbations by aerosol optical depth and albedo in the evaluation of the RAF the ratios of UV irradiances to total irradiances were evaluated. (Author)

  1. Repair of 313-nm induced lesions and photoprotection in yeast Candida guilliermondii

    International Nuclear Information System (INIS)

    Fraikin, G.Y.; Pospelov, M.E.; Rubin, L.B.

    1977-01-01

    The present communication is concerned with the effects of near-UV radiation (300-380 nm) on yeast Candida guilliermondii. It was found that certain doses of 313 nm irradiation caused inactivation of the yeast which was exhibited in a way different from the lethal action of far-UV radiation. It was also found that the cells inactivated by 313 nm are capable of recovering vitality, if incubated for some time in a non-nutrient medium. The yeast inactivated by far-UV radiation also proved to be capable of recovering, though to a lesser degree. Both 334 nm radiation and non-lethal doses at 313 nm induced the photoprotective effect against far-UV damage. The effect was exhibited if there was a certain time interval (2-4 h) between the exposures to photoprotective light and subsequent far-UV radiation. Within this time interval the extent of photoprotection was dependent on temperature. (author)

  2. Radiation hardness evaluation of the commercial 150 nm CMOS process using 60Co source

    International Nuclear Information System (INIS)

    Carna, M; Havranek, M; Hejtmanek, M; Janoska, Z; Marcisovsky, M; Neue, G; Tomasek, L; Vrba, V

    2014-01-01

    We present a study of radiation effects on MOSFET transistors irradiated with a 60 Co source to a total absorbed dose of 1.5 Mrad. The transistor test structures were manufactured using a commercial 150 nm CMOS process and are composed of transistors of different types (NMOS and PMOS), dimensions and insulation from the bulk material by means of deep n-wells. We have observed a degradation of electrical characteristics of both PMOS and NMOS transistors, namely a large increase of the leakage current of the NMOS transistors after irradiation

  3. 46 CFR 169.315 - Ventilation (other than machinery spaces).

    Science.gov (United States)

    2010-10-01

    ... section is satisfied, a vessel having only a natural ventilation system must satisfy the following: V/A≥1... 46 Shipping 7 2010-10-01 2010-10-01 false Ventilation (other than machinery spaces). 169.315... SCHOOL VESSELS Construction and Arrangement Hull Structure § 169.315 Ventilation (other than machinery...

  4. Measurement of the quantum efficiency of TMAE and TEA from threshold to 120 nm

    International Nuclear Information System (INIS)

    Holroyd, R.A.; Preses, J.M.; Woody, C.L.; Johnson, R.A.

    1986-01-01

    Several existing and planned high energy physics experiments incorporate detectors which use either TMAE (tetrakis-dimethylaminoethylene) or TEA (triethylamine) as their photosensitive agent. Understanding the operation of these devices requires knowledge of the absolute photoionization quantum efficiencies and absorption lengths of TMAE and TEA. In an experiment performed at the National Synchrotron Light source at Brookhaven National Laboratory, we have measured these parameters from 120 nm to 280 nm. The quantum efficiencies were normalized to the known photoionization yields of benzene and cis-2-butene. The results of these measurements and details of the experiment are presented in this paper

  5. The use of shore wave ultraviolet radiation for disinfection in operating rooms

    International Nuclear Information System (INIS)

    Baanrud, H.; Moan, J.

    1999-01-01

    Over a number of years short wave ultraviolet radiation (UVC;200-280 nm) has been used to disinfect air and surfaces in operating rooms, patient rooms and laboratories, as well as air in ventilation ducts. Despite the well-documented effect of ultraviolet radiation on air quality, this technology has been relatively little used. One advantage of this method is that the UVC sources ensure a continuous reduction in the number of airborne microorganisms that are generated all the time. There are, however, some disadvantages with this method. Human exposure to ultraviolet C may cause keratoconjunctivitis and erythema and requires protection of the skin and the eyes of people exposed to levels above recommended exposure limits. However, by enclosing the UVC sources or by irradiation in the absence of human activity, human exposure is eliminated. These and other aspects concerning the use of short wave ultraviolet radiation as a disinfection agent in operating rooms are discussed in this article

  6. 5 CFR 315.705 - Employees serving under transitional or veterans recruitment appointments.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Employees serving under transitional or veterans recruitment appointments. 315.705 Section 315.705 Administrative Personnel OFFICE OF PERSONNEL...-Conditional Employment From Other Types of Employment § 315.705 Employees serving under transitional or...

  7. [The influence of pulsed low-intensity laser radiation of the red (635 nm) and infrared (904 nm) spectra on the human mesenchymal stem cells in vitro].

    Science.gov (United States)

    Moskvin, S V; Kliuchnikov, D Iu; Antipov, E V; Volchkov, S E; Kiseleva, O N

    2014-01-01

    Mesenchymal stem cells (MSC) have for a long time been an object of investigation with a view to elucidating the prospects for their application in clinical medicine and cosmetology. One of the approaches to the non-specific regulation of the activity of these cells at the stage of preliminary in vitro combination is the treatment with low-intensity laser radiation (LILR). The objective of the present study was to evaluate the possibility of using pulsed LILR of the infrared and red spectra for this purpose. We used the 4th passage adhesive MSC cultures based at the umbilical tissue of a donor who gave the informed consent to participate in the study. The source of illumination was a Lazmik-VLOK laser therapeutic apparatus (RU No RZN 2014/1410 dated 06.02.2014) with the matrix laser infrared radiation heads (wavelength 904 nm, light pulse length 108 ns, frequency 1500 Hz). The apparatus was operated either in the multi-frequency Lazmik regime [Moskvin S.V., 2014] with mean power density 0.05 and 0.14 mW/cm2 and the red spectrum (wavelength 635 nm, light pulse length 144 ns, frequency 1500 Hz) or in the multi-frequency Lazmik regime [Moskvin S.V., 2014] with mean power density 0.03 and 0.12. The exposition was 5 min in both regimes. The study has demonstrated that neither the morphological structure nor the viability of mesenchymal stem cells changed under the influence of energy and time parameters used in experiments. The number of cells was shown to slightly increase in comparison with control. The most pronounced effect was documented after illumination with pulse infrared (904 nm) LILR in the multi-frequency Lazmik regime. The maximum effect was observed during a period between days 1 and 3 of cultivation.

  8. Inhibition and recovery of semiconservative DNA synthesis in normal and solar UV sensitive ICR 2A frog cell lines following the induction of non-dimer DNA damage by sunlamp UV > 315 nm

    Energy Technology Data Exchange (ETDEWEB)

    Rosenstein, B.S. (Brown Univ., Providence, RI (USA). Dept. of Radiation Medicine)

    1989-08-01

    Cultures of solar UV-sensitive cell lines DRP 36 and DRP 153, and of the parental ICR 2A cell line, were exposed to 150 kJ/m{sup 2} of sunlamp UV>315nm plus photoreactivating light, resulting in the induction primarily of non-dimer DNA damage. Following either 0, 3, 6, 12 or 24 h incubation, cultures were pulse-labelled with ({sup 3}H) thymidine, and the synthesis of different size classes of replicon intermediates measured using alkaline step elution assay. For all three cell lines tested, an immediate depression of low molecular weight DNA synthesis was observed, followed by inhibition of all size classes of replicon intermediates. Within 12 h following irradiation, recovery of DNA synthesis was observed, generally most apparent for low molecular weight DNA. The ICR 2A cells exhibited a nearly full recovery in all size classes of DNA synthesized by 24 h. A much smaller recovery of continued inhibition was primarily in the synthesis of full replicon size DNA, and most pronounced for DRP 36 cells. (author).

  9. Method for evaluation of radiative properties of glass samples

    Energy Technology Data Exchange (ETDEWEB)

    Mohelnikova, Jitka [Faculty of Civil Engineering, Brno University of Technology, Veveri 95, 602 00 Brno (Czech Republic)], E-mail: mohelnikova.j@fce.vutbr.cz

    2008-04-15

    The paper presents a simple calculation method which serves for an evaluation of radiative properties of window glasses. The method is based on a computer simulation model of the energy balance of a thermally insulated box with selected glass samples. A temperature profile of the air inside of the box with a glass sample exposed to affecting radiation was determined for defined boundary conditions. The spectral range of the radiation was considered in the interval between 280 and 2500 nm. This interval is adequate to the spectral range of solar radiation affecting windows in building facades. The air temperature rise within the box was determined in a response to the affecting radiation in the time between the beginning of the radiation exposition and the time of steady-state thermal conditions. The steady state temperature inside of the insulated box serves for the evaluation of the box energy balance and determination of the glass sample radiative properties. These properties are represented by glass characteristics as mean values of transmittance, reflectance and absorptance calculated for a defined spectral range. The data of the computer simulations were compared to experimental measurements on a real model of the insulated box. Results of both the calculations and measurements are in a good compliance. The method is recommended for preliminary evaluation of window glass radiative properties which serve as data for energy evaluation of buildings.

  10. Saturable absorber Q- and gain-switched all-Yb3+ all-fiber laser at 976 and 1064 nm.

    Science.gov (United States)

    Tsai, Tzong-Yow; Fang, Yen-Cheng; Huang, Huai-Min; Tsao, Hong-Xi; Lin, Shih-Ting

    2010-11-08

    We demonstrate a novel passively pulsed all-Yb3+ all-fiber laser pumped by a continuous-wave 915-nm pump laser diode. The laser was saturable absorber Q-switched at 976 nm and gain-switched at 1064 nm, using the method of mode-field-area mismatch. With a pump power of 
105 mW, the laser iteratively produced a 976-nm pulse with an energy of 2.8 μJ and a duration of 280 ns, followed by a 1064-nm pulse with 1.1 μJ and a 430-ns duration at a repetition rate of 9 kHz. A set of rate equations was established to simulate the self-balancing mechanism and the correlation between the Q- and gain-switched photon numbers and the populations of the gain and absorber fibers.

  11. Transparent cellulose/polyhedral oligomeric silsesquioxane nanocomposites with enhanced UV-shielding properties.

    Science.gov (United States)

    Feng, Ye; Zhang, Jinming; He, Jiasong; Zhang, Jun

    2016-08-20

    The solubility of eight types of polyhedral oligomeric silsesquioxane (POSS) derivatives in an ionic liquid 1-allyl-3-methylimidazolium chloride (AmimCl) and the dispersion of POSS in cellulose matrix were examined. Only a special POSS containing both aminophenyl and nitrophenyl groups (POSS-AN, NH2:NO2=2:6) was selected to prepare nanocomposites, because of its good solubility in AmimCl and high stability during the preparation process. POSS-AN nanoparticles were uniformly dispersed in a cellulose matrix with a size of 30-40nm, and so the resultant cellulose/POSS-AN nanocomposite films were transparent. The mechanical properties of the films achieved a maximum tensile strength of 190MPa after addition of 2wt% POSS-AN. Interestingly, all of the cellulose/POSS-AN films exhibited high UV-absorbing capability. For the 15wt% cellulose/POSS-AN film, the transmittance of UVA (315-400nm) and UVB (280-315nm) was only 9.1% and nearly 0, respectively. The UV aging and shielding experiments showed that the transparent cellulose/POSS-AN nanocomposite films possessed anti-UV aging and UV shielding properties. Copyright © 2016 Elsevier Ltd. All rights reserved.

  12. 24 CFR 214.315 - Recordkeeping.

    Science.gov (United States)

    2010-04-01

    ... of clients with the same housing need. (f) Group education file. The housing counseling agency must... COUNSELING PROGRAM Program Administration § 214.315 Recordkeeping. (a) Recordkeeping system. Each participating housing counseling agency must maintain a recordkeeping system. The system must permit HUD to...

  13. 31 CFR 315.83 - Reissue or payment on dissolution of corporation or partnership.

    Science.gov (United States)

    2010-07-01

    ... corporation or partnership. 315.83 Section 315.83 Money and Finance: Treasury Regulations Relating to Money... Private Organizations (Corporations, Associations, Partnerships, etc.) and Governmental Agencies, Units and Officers § 315.83 Reissue or payment on dissolution of corporation or partnership. (a...

  14. Thermoluminescence analysis for detection of irradiated food - luminescence characteristics of minerals for different types of radiation and radiation doses

    International Nuclear Information System (INIS)

    Soika, C.; Delincée, H.

    2000-01-01

    Federal Research Centre for Nutrition, Institute of Nutritional Physiology, Haid-und-Neu-Straße 9, 76131 Karlsruhe (Germany) Thermoluminescence analysis is used to detect radiation processing of foods which are contaminated with sand or dust. Silicate minerals are isolated, their radiation-induced luminescence is measured and compared to the thermoluminescence from a second measurement after exposure to a dexned radiation dose (normalization). In the present study, the mineral mixture *sand+ and its main components feldspar and quartz were investigated for their thermoluminescence behaviour using different types of radiation, in order to determine adequate radiation sources for the purpose of normalization. The material was irradiated with types of ionizing radiation commonly used for commercial food irradiation, i.e. accelerated electrons with beam energies of 5 MeV as well as 10 MeV, and 60 Co--rays. After thermoluminescence measurements, samples were re-irradiated using either accelerated electrons with beam energies of 2 MeV, 5 MeV or 10 MeV, or 60 Co--rays, 90 Sr--rays or ultraviolet rays (200}280 nm). Evaluation of the xrst and corresponding second glow curve revealed that their shapes depend on the type of minerals in the mixture. The second radiation treatment (normalization) is satisfactory when accelerated electrons (2, 5 and 10 MeV) as well as 60 Co--rays and 90 Sr--rays are employed. Normalization with ultraviolet rays, however, has only a limited range of use

  15. Cyclobutane pyrimidine dimers are photosensitised by carprofen plus UVA in human HaCaT cells.

    Science.gov (United States)

    Robinson, K S; Traynor, N J; Moseley, H; Ferguson, J; Woods, J A

    2010-06-01

    Every year in the UK about 75,000 cases of non-melanoma skin cancer (NMSC) are registered, and about 9500 people are diagnosed with cutaneous melanoma (CM). The main risk factor for these cancers is exposure to sunlight. The effects of light on skin are wavelength dependent, with wavelengths in the UVB waveband (280-315 nm) being the most carcinogenic. UVB is directly absorbed by DNA, producing dimeric pyrimidine photoproducts including cyclobutane pyrimidine dimers (CPD) and pyrimidine (6-4) pyrimodone photoproducts (6-4PP). However UVA (315-400 nm) can also produce CPD, induce skin tumours in mice, and has been shown to be mutagenic in cell culture. Although the precise role of UVA in human skin cancer remains to be elucidated, it comprises the major portion of solar UV radiation, transmits through window glass and can be delivered in high doses from tanning lamps. Non-steroidal anti-inflammatory drugs (NSAIDs), in particular the 2-aryl propionic acid derivatives, are a well-documented group of photosensitising chemicals producing clinical phototoxic and photoallergic reactions. We have used carprofen, a model compound from this group to see if it could amplify the effects of UVA and contribute to the formation of CPD by UVA. Preliminary work has shown that carprofen combined with low doses of UVA (lambda(max): 365 nm; 5 J/cm(2)) can produce both strand breaks (SB) and CPD in human skin or blood cells. CPD were detected indirectly by both an immunofluorescence method and as T4 endonuclease V sensitive sites in the comet assay. These findings show that compounds other than fluoroquinolones and psoralen derivatives may contribute to CPD formation in skin cells in combination with UVA. Copyright 2010 Elsevier Ltd. All rights reserved.

  16. Mechanistic comparison of pulse laser induced phase separation of particulates from cellulose paper at 213 nm and 532 nm

    International Nuclear Information System (INIS)

    Arif, S.; Forster, M.; Kautek, W.; Bushuk, S.; Kouzmouk, A.; Tatur, H.; Batishche, S.

    2013-01-01

    The laser-induced phase separation of charcoal particles on additive-free cotton linters cellulose paper was investigated by electron and optical microscopy, colorimetry, and diffuse reflectance FT-IR. The fibre bundles were vaporised in depth of several 10 μm above destruction fluence thresholds using visible 532 nm radiation. This is in contrast to mid-ultraviolet 213 nm radiation, where only the top fibre bundles were modified and partially evaporated. The colorimetric lightness results generally represented the cleaning status, whereas the colorimetric yellowing data represented irreversible chemical and/or photochemical changes. Charcoal-contaminated paper treated with visible and mid-ultraviolet radiation exhibited yellowing, whereas uncontaminated did not. This suggests that the electron-rich plasma generated by the evaporation of the particles heats the adjacent substrate and also excludes oxygen. Mid-ultraviolet, in contrast to visible radiation, shows particle removal always accompanied by paper destruction. IR spectroscopy results suggest cross-linking by ether bonds near the destruction threshold, but do not prove the formation of oxidation products and double bonds as the basis of the yellowing. A ''cleaning window'' between the cleaning threshold (0.1 J/cm 2 ) and the paper destruction threshold (2.9 J/cm 2 ) with a pulse number of 2 is provided by visible 532 nm laser treatment. (orig.)

  17. Competitive interaction in plant populations exposed to supplementary ultraviolet-B radiation

    International Nuclear Information System (INIS)

    Fox, F.M.; Caldwell, M.M.; Utah State Univ., Logan

    1978-01-01

    Changes in plant growth and competitive balance between pairs of competing species were documented as a result of supplementary ultraviolet-B radiation (principally in the 290-315 nm waveband) under field conditions. This component of the terrestrial solar spectrum would be intensified if the atmospheric ozone layer were reduced. A method for calculating and statistically analyzing relative crowding coefficients was developed and used to evaluate the competitive status of the species pairs sown in a modified replacement series. The effect of the supplementary UV-B irradiance was generally detrimental to plant growth, and was reflected in decreased leaf area, biomass, height and density as well as changes competitive balance for various species. For some species, interspecific competition apparently accentuated the effect of the UV-B radiation, while more intense intraspecific competition may have had the same effect for other species. A few species when grown in a situation of more severe mutual interspecific competition exhibited enhanced growth under the UV-B radiation treatment. This, however, was usually associated with a detrimental effect of the radiation, on its competitor and thus was likely the result of its improved competitive circumstance rather than a benefical physiological effect of the radiation. (orig.) [de

  18. Radiation induced processes in moss cells. Short term and long term radiation responses of special interest after microbeam uv irradiation of the haploid moss cells of Funaria hygrometrica

    Energy Technology Data Exchange (ETDEWEB)

    Doehren, R v [Mainz Univ. (F.R. Germany). Inst. fuer Biochemie

    1975-01-01

    The moss F.h. shows apical growth in the protonema cells which spread radially from the spor. Every apical daughter cell during the state of 'Caulonema' and just before in the state of 'Caulonema Primanen' initiates cell division as soon as more than twice the length of the mother cell is reached. All this allows to follow radiation effects in single cells conveniently. UV irradiation on the range of 254 nm and 280 nm delivered at different parts of the cell area delays cell division markedly may suppress it, and is able to stop the process of growing in relation to the delivered dose and to the irradiated area as well. In case of irradiation of the area next to where the membrane is just being formed - that is to say next to the phragmoplast - the new membrane will be wrongly oriented. In particular giant cells are occurring in the case of nucleus irradiation during early prophase.

  19. 27 CFR 19.315 - Removal or destruction of distilling material.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Removal or destruction of distilling material. 19.315 Section 19.315 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND...) spirits, (2) alcoholic beverages, or (3) vinegar by the vaporizing process; or (c) for destruction. The...

  20. 21 CFR 173.280 - Solvent extraction process for citric acid.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Solvent extraction process for citric acid. 173.280... HUMAN CONSUMPTION Solvents, Lubricants, Release Agents and Related Substances § 173.280 Solvent extraction process for citric acid. A solvent extraction process for recovery of citric acid from...

  1. Correlation between cell survival and DNA single-strand break repair proficiency in the Chinese hamster ovary cell lines AA8 and EM9 irradiated with 365-nm ultraviolet-A radiation

    Energy Technology Data Exchange (ETDEWEB)

    Churchill, M.E.; Peak, J.G.; Peak, M.J. (Argonne National Lab., IL (USA))

    1991-02-01

    Cell survival parameters and the induction and repair of DNA single-strand breaks were measured in two Chinese hamster ovary cell lines after irradiation with monochromatic UVA radiation of wavelength 365 nm. The radiosensitive mutant cell line EM9 is known to repair ionizing-radiation-induced single-strand breaks (SSB) more slowly than the parent line AA8. EM9 was determined to be 1.7-fold more sensitive to killing by 365-nm radiation than AA8 at the 10% survival level, and EM9 had a smaller shoulder region on the survival curve ({alpha} = 1.76) than AA8 ({alpha} = 0.62). No significant differences were found between the cell lines in the initial yields of SSB induced either by {gamma}-radiation (as determined by alkaline sucrose gradient sedimentation) or by 365-nm UVA (as determined by alkaline elution). For measurement of initial SSB, cells were irradiated at 0.5{sup o}C to minimize DNA repair processes. Rejoining of 365-nm induced SSB was measured by irradiating cells at 0.5{sup o}C, allowing them to repair at 37{sup o}C in full culture medium, and then quantitating the remaining SSB by alkaline elution. The repair of these breaks followed biphasic kinetics in both cell lines. EM9 repaired the breaks more slowly (T{sub 1/2} values of 1.3 and 61.3 min) than did AA8 (T{sub 1/2} values of 0.9 and 53.3 min), and EM9 also left more breaks unrepaired 90 min after irradiation (24% vs 8% for AA8). Thus, the sensitivity of EM9 to 365-nm radiation correlated with its deficiency in repairing DNA lesions revealed as SSB in alkaline elution. These results suggest that DNA may be a critical target in 365-nm induced cellular lethality and that the ability of AA8 and EM9 cells to repair DNA strand breaks may be related to their ability to survive 365-nm radiation. (author).

  2. Fiber-based broadband black-light source

    OpenAIRE

    Sylvestre , Thibaut; Lee , Min Won; Ragueh , A. R.; Stiller , Birgit; Fanjoux , Gil; Barviau , B.; Mussot , A.; Kudlinski , A.

    2012-01-01

    International audience; Black-Light or Wood's lamp refers to sources that emit long-wavelength ultraviolet radiation (UV-A) from 315 nm and little visible light till 410 nm (blue). In this paper, we present a new fibre-based source of "black light", a source that emits broadband ultraviolet radiation but only small amounts of visible light and no infrared light. We made this source by pumping a specially designed silica photonic crystal fibre (PCF) with 355 nm light pulses from a Q-switched f...

  3. Generation of continuous-wave 194 nm laser for mercury ion optical frequency standard

    Science.gov (United States)

    Zou, Hongxin; Wu, Yue; Chen, Guozhu; Shen, Yong; Liu, Qu; Precision measurement; atomic clock Team

    2015-05-01

    194 nm continuous-wave (CW) laser is an essential part in mercury ion optical frequency standard. The continuous-wave tunable radiation sources in the deep ultraviolet (DUV) region of the spectrum is also serviceable in high-resolution spectroscopy with many atomic and molecular lines. We introduce a scheme to generate continuous-wave 194 nm radiation with SFM in a Beta Barium Borate (BBO) crystal here. The two source beams are at 718 nm and 266 nm, respectively. Due to the property of BBO, critical phase matching (CPM) is implemented. One bow-tie cavity is used to resonantly enhance the 718 nm beam while the 266 nm makes a single pass, which makes the configuration easy to implement. Considering the walk-off effect in CPM, the cavity mode is designed to be elliptical so that the conversion efficiency can be promoted. Since the 266 nm radiation is generated by a 532 nm laser through SHG in a BBO crystal with a large walk-off angle, the output mode is quite non-Gaussian. To improve mode matching, we shaped the 266 nm beam into Gaussian modes with a cylindrical lens and iris diaphragm. As a result, 2.05 mW 194 nm radiation can be generated. As we know, this is the highest power for 194 nm CW laser using SFM in BBO with just single resonance. The work is supported by the National Natural Science Foundation of China (Grant No. 91436103 and No. 11204374).

  4. 34 CFR 280.32 - How is priority given to applicants?

    Science.gov (United States)

    2010-07-01

    ..., the location of the magnet school within the LEA—impacts on the applicant's ability to successfully... 34 Education 1 2010-07-01 2010-07-01 false How is priority given to applicants? 280.32 Section 280.32 Education Regulations of the Offices of the Department of Education OFFICE OF ELEMENTARY AND...

  5. Radiation-Induced Short Channel (RISCE) and Narrow Channel (RINCE) Effects in 65 and 130 nm MOSFETs

    CERN Document Server

    Faccio, F; Cornale, D; Paccagnella, A; Gerardin, S

    2015-01-01

    The behavior of transistors in commercial-grade complementary metal-oxide semiconductor technologies in the 65 and 130 nm nodes has been explored up to a total ionizing dose of 1 Grad. The large dose tolerance of the thin gate oxide is confirmed, but defects in the spacer and STI oxides have a strong effect on the performance of the transistors. A radiation-induced short channel effect is traced to charge trapping in the spacers used for drain engineering, while a radiation-induced narrow channel effect is due to defect generation in the lateral isolation oxide (STI). These strongly degrade the electrical characteristics of short and narrow channel transistors at high doses, and their magnitude depends on the applied bias and temperature during irradiation in a complex way.

  6. 46 CFR 280.11 - Example of calculation and sample report.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Example of calculation and sample report. 280.11 Section... OPERATORS § 280.11 Example of calculation and sample report. (a) Example of calculation. The provisions of this part may be illustrated by the following example: Company A operates several vessels engaged in...

  7. 10 CFR 603.315 - Advantages of a fixed-support TIA.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Advantages of a fixed-support TIA. 603.315 Section 603.315... fixed-support TIA. In situations where the use of a fixed-support TIA is permissible (see §§ 603.305 and... TIA, the contracting officer can eliminate or reduce some post-award requirements that sometimes are...

  8. Mechanistic comparison of pulse laser induced phase separation of particulates from cellulose paper at 213 nm and 532 nm

    Energy Technology Data Exchange (ETDEWEB)

    Arif, S.; Forster, M.; Kautek, W. [University of Vienna, Department of Physical Chemistry, Wien (Austria); Bushuk, S.; Kouzmouk, A.; Tatur, H.; Batishche, S. [National Academy of Sciences of the Republic of Belarus, Institute of Physics, Minsk (Belarus)

    2013-02-15

    The laser-induced phase separation of charcoal particles on additive-free cotton linters cellulose paper was investigated by electron and optical microscopy, colorimetry, and diffuse reflectance FT-IR. The fibre bundles were vaporised in depth of several 10 {mu}m above destruction fluence thresholds using visible 532 nm radiation. This is in contrast to mid-ultraviolet 213 nm radiation, where only the top fibre bundles were modified and partially evaporated. The colorimetric lightness results generally represented the cleaning status, whereas the colorimetric yellowing data represented irreversible chemical and/or photochemical changes. Charcoal-contaminated paper treated with visible and mid-ultraviolet radiation exhibited yellowing, whereas uncontaminated did not. This suggests that the electron-rich plasma generated by the evaporation of the particles heats the adjacent substrate and also excludes oxygen. Mid-ultraviolet, in contrast to visible radiation, shows particle removal always accompanied by paper destruction. IR spectroscopy results suggest cross-linking by ether bonds near the destruction threshold, but do not prove the formation of oxidation products and double bonds as the basis of the yellowing. A ''cleaning window'' between the cleaning threshold (0.1 J/cm{sup 2}) and the paper destruction threshold (2.9 J/cm{sup 2}) with a pulse number of 2 is provided by visible 532 nm laser treatment. (orig.)

  9. Complementary UV-Absorption of Mycosporine-like Amino Acids and Scytonemin is Responsible for the UV-Insensitivity of Photosynthesis in Nostoc flagelliforme

    Science.gov (United States)

    Ferroni, Lorenzo; Klisch, Manfred; Pancaldi, Simonetta; Häder, Donat-Peter

    2010-01-01

    Mycosporine-like amino acids (MAAs) and scytonemin are UV-screening compounds that have presumably appeared early in the history of life and are widespread in cyanobacteria. Natural colonies of the UV-insensitive Nostoc flagelliforme were found to be especially rich in MAAs (32.1 mg g DW−1), concentrated in the glycan sheath together with scytonemin. MAAs are present in the form of oligosaccharide-linked molecules. Photosystem II activity, measured using PAM fluorescence and oxygen evolution, was used as a most sensitive physiological parameter to analyse the effectiveness of UV-protection. Laboratory experiments were performed under controlled conditions with a simulated solar radiation specifically deprived of UV-wavebands with cut-off filters (295, 305, 320, 345 and 395 nm). The UV-insensitivity of N. flagelliforme was found to cover the whole UV-A (315–400 nm) and UV-B (280–320 nm) range and is almost certainly due to the complementary UV-absorption of MAAs and scytonemin. The experimental approach used is proposed to be suitable for the comparison of the UV-protection ability in organisms that differ in their complement of UV-sunscreen compounds. Furthermore, this study performed with a genuinely terrestrial organism points to the relevance of marine photoprotective compounds for life on Earth, especially for the colonization of terrestrial environments. PMID:20161974

  10. Complementary UV-Absorption of Mycosporine-like Amino Acids and Scytonemin is Responsible for the UV-Insensitivity of Photosynthesis in Nostoc flagelliforme

    Directory of Open Access Journals (Sweden)

    Donat-Peter Häder

    2010-01-01

    Full Text Available Mycosporine-like amino acids (MAAs and scytonemin are UV-screening compounds that have presumably appeared early in the history of life and are widespread in cyanobacteria. Natural colonies of the UV-insensitive Nostoc flagelliforme were found to be especially rich in MAAs (32.1 mg g DW-1, concentrated in the glycan sheath together with scytonemin. MAAs are present in the form of oligosaccharide-linked molecules. Photosystem II activity, measured using PAM fluorescence and oxygen evolution, was used as a most sensitive physiological parameter to analyse the effectiveness of UV-protection. Laboratory experiments were performed under controlled conditions with a simulated solar radiation specifically deprived of UV-wavebands with cut-off filters (295, 305, 320, 345 and 395 nm. The UV-insensitivity of N. flagelliforme was found to cover the whole UV-A (315–400 nm and UV-B (280–320 nm range and is almost certainly due to the complementary UV-absorption of MAAs and scytonemin. The experimental approach used is proposed to be suitable for the comparison of the UV-protection ability in organisms that differ in their complement of UV-sunscreen compounds. Furthermore, this study performed with a genuinely terrestrial organism points to the relevance of marine photoprotective compounds for life on Earth, especially for the colonization of terrestrial environments.

  11. 30 CFR 280.29 - Will MMS monitor the environmental effects of my activity?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Will MMS monitor the environmental effects of my activity? 280.29 Section 280.29 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE... Obligations Under This Part Environmental Issues § 280.29 Will MMS monitor the environmental effects of my...

  12. 30 CFR 280.73 - Will MMS share data and information with coastal States?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Will MMS share data and information with coastal States? 280.73 Section 280.73 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE... Data Requirements Protections § 280.73 Will MMS share data and information with coastal States? (a) We...

  13. Effect of ultraviolet radiation in the photo-oxidation of High Density Polyethylene and Biodegradable Polyethylene films

    International Nuclear Information System (INIS)

    Martínez-Romo, A; Mota, R González; Bernal, J J Soto; Candelas, I Rosales; Reyes, C Frausto

    2015-01-01

    One of the most widely used plastics in the world is the High density polyethylene (HDPE), it is a stable material due to its carbon-carbon bonds, causing their slow degradation; which is why we are looking for alternative ways to accelerate the degradation process of this polymer. An alternative is the addition of oxidized groups in its molecular structure, which results in the development of polymers susceptible to biodegradation (PE-BIO). In this paper, HDPE and PE-BIO films were exposed to UV-B radiation (320-280 nm) at different exposure times, 0-60 days. The effects of UV radiation in samples of HDPE and PE-BIO were characterized using infrared spectroscopy with attenuated total reflectance (ATR). The results show that the exposed materials undergo changes in their molecular structure, due to the infrared bands formed which corresponds to the photo-oxidation of HDPE and PE films when submitted to UV-B radiation

  14. 30 CFR 280.27 - When may MMS cancel my permit?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false When may MMS cancel my permit? 280.27 Section... Part Interrupted Activities § 280.27 When may MMS cancel my permit? The RD may cancel a permit at any time. (a) If we cancel your permit, the RD will advise you by certified or registered mail 30 days...

  15. Disentangling the effects of solar radiation, wrack macroalgae and beach macrofauna on associated bacterial assemblages.

    Science.gov (United States)

    Rodil, Iván F; Fernandes, Joana P; Mucha, Ana P

    2015-12-01

    Wrack detritus plays a significant role in shaping community dynamics and food-webs on sandy beaches. Macroalgae is the most abundant beach wrack, and it is broken down by the combination of environmental processes, macrofauna grazing, and microbial degradation before returning to the sea as nutrients. The role of solar radiation, algal species and beach macrofauna as ecological drivers for bacterial assemblages associated to wrack was investigated by experimental manipulation of Laminaria ochroleuca and Sargassum muticum. We examined the effects of changes in solar radiation on wrack-associated bacterial assemblages by using cut-off filters: PAR + UVA + UVB (280-700 nm; PAB), PAR + UVA (320-700 nm; PA), PAR (400-700 nm; P), and a control with no filter (C). Results showed that moderate changes in UVR are capable to promote substantial differences on bacterial assemblages so that wrack patches exposed to full sunlight treatments (C and PAB) showed more similar assemblages among them than compared to patches exposed to treatments that blocked part of the solar radiation (P and PA). Our findings also suggested that specific algal nutrient quality-related variables (i.e. nitrogen, C:N ratio and phlorotannins) are main determinants of bacterial dynamics on wrack deposits. We showed a positive relationship between beach macrofauna, especially the most abundant and active wrack-users, the amphipod Talitrus saltator and the coleopteran Phaleria cadaverina, and both bacterial abundance and richness. Moderate variations in natural solar radiation and shifts in the algal species entering beach ecosystems can modify the role of wrack in the energy-flow of nearshore environments with unknown ecological implications for coastal ecosystems. Copyright © 2015 Elsevier Ltd. All rights reserved.

  16. Radiation from an equilibrium CO2-N2 plasma in the [250-850 nm] spectral region: II. Spectral modelling

    International Nuclear Information System (INIS)

    Silva, M Lino da; Vacher, D; Andre, P; Faure, G; Dudeck, M

    2008-01-01

    In the first part of this work, described in a previous paper, the thermodynamic conditions in an atmospheric pressure inductively coupled CO 2 -N 2 plasma have been determined, and the radiation emission spectrum has been measured and calibrated in the [250-850 nm] spectral region. In the second part of this work, a synthetic radiation spectrum is obtained taking into account (a) the geometry of the plasma torch and (b) the local thermodynamic conditions of the plasma. This synthetic spectrum has then been compared against the measured spectrum. The good agreement between the two spectra allows validating the spectral database of the line-by-line code SPARTAN for the simulation of the radiative emission of CO 2 -N 2 plasmas from the near-UV to the near-IR spectral region.

  17. Physical, biochemical and physiological effects of ultraviolet radiation on Brassica napus and Phaseolus vulgaris

    International Nuclear Information System (INIS)

    Cen Yan-Ping.

    1993-01-01

    In order to follow some of the changes induced by ultraviolet-B (UV-B, 280-320 nm) radiation in Phaseolus vulgaris and Brassica napus, experiments were designed to localize sites of changes in leaves and to correlate some of the physiological and biochemical changes with penetration of UV-B radiation. B.napus was exposed to 8.9 kJ m -2 day -1 biologically effective UV-B radiation (UV-B BE ). The penetration of UV-B radiation into the leaf was followed using a quartz fibre optic microprobe. Monochromatic radiation at 310 nm was decreased by ca 50 and 34% in the adaxial and abaxial epidermis, respectively, in plants not exposed to UV-B, whereas the radiation was decreased by ca 70 and 42%, respectively, in the same region in UV-treated plants. Polychromatic radiation showed a wavelength dependent change mainly for the collimated radiation. The results correlated with the distribution of phenolic compounds analysed from 40 μm paradermal leaf sections. The first adaxial section (40μm) contained 35% of the whole leaf sample flavonoid glycosides in control plants, and 66% in UV-treated plants. Hydroxycinnamic acid derivatives increased by 26% in UV-treated plants relative to controls. The ratio of quercetin to kaempferol derivatives increased from 0.11 in controls to 0.91 in leaves of UV-treated plants. The leaf epidermis protected the inner leaf tissue where most of the photosynthetic apparatus is located. P. vulgaris was subjected to 6.17 kJ m -2 day -1 UV-B BE with different levels of visible light. The largest UV-induced changes in photosynthesis, chlorophyll, carotenoids, UV-screening pigments, and surface leaf reflectance occurred under growth conditions of low levels of visible light together with UV radiation

  18. Physical, biochemical and physiological effects of ultraviolet radiation on Brassica napus and Phaseolus vulgaris

    Energy Technology Data Exchange (ETDEWEB)

    Cen Yan-Ping

    1993-12-31

    In order to follow some of the changes induced by ultraviolet-B (UV-B, 280-320 nm) radiation in Phaseolus vulgaris and Brassica napus, experiments were designed to localize sites of changes in leaves and to correlate some of the physiological and biochemical changes with penetration of UV-B radiation. B.napus was exposed to 8.9 kJ m{sup -2} day{sup -1} biologically effective UV-B radiation (UV-B{sub BE}). The penetration of UV-B radiation into the leaf was followed using a quartz fibre optic microprobe. Monochromatic radiation at 310 nm was decreased by ca 50 and 34% in the adaxial and abaxial epidermis, respectively, in plants not exposed to UV-B, whereas the radiation was decreased by ca 70 and 42%, respectively, in the same region in UV-treated plants. Polychromatic radiation showed a wavelength dependent change mainly for the collimated radiation. The results correlated with the distribution of phenolic compounds analysed from 40 {mu}m paradermal leaf sections. The first adaxial section (40{mu}m) contained 35% of the whole leaf sample flavonoid glycosides in control plants, and 66% in UV-treated plants. Hydroxycinnamic acid derivatives increased by 26% in UV-treated plants relative to controls. The ratio of quercetin to kaempferol derivatives increased from 0.11 in controls to 0.91 in leaves of UV-treated plants. The leaf epidermis protected the inner leaf tissue where most of the photosynthetic apparatus is located. P. vulgaris was subjected to 6.17 kJ m{sup -2} day{sup -1} UV-B{sub BE} with different levels of visible light. The largest UV-induced changes in photosynthesis, chlorophyll, carotenoids, UV-screening pigments, and surface leaf reflectance occurred under growth conditions of low levels of visible light together with UV radiation.

  19. Prototyping the HPDP Chip on STM 65 NM Process

    Science.gov (United States)

    Papadas, C.; Dramitinos, G.; Syed, M.; Helfers, T.; Dedes, G.; Schoellkopf, J.-P.; Dugoujon, L.

    2011-08-01

    Currently Astrium GmbH is involved in the of the High Performance Data Processor (HPDP) development programme for telecommunication applications under a DLR contract. The HPDP project targets the implementation of the commercially available reconfigurable array processor IP (XPP from the company PACT XPP Technologies) in a radiation hardened technology.In the current complementary development phase funded under the Greek Industry Incentive scheme, it is planned to prototype the HPDP chip in commercial STM 65 nm technology. In addition it is also planned to utilise the preliminary radiation hardened components of this library wherever possible.This abstract gives an overview of the HPDP chip architecture, the basic details of the STM 65 nm process and the design flow foreseen for the prototyping. The paper will discuss the development and integration issues involved in using the STM 65 nm process (also including the available preliminary radiation hardened components) for designs targeted to be used in space applications.

  20. The Effects of UV Radiation on Chloroplast Clumping and Photosynthesis in the Seagrass Halophila stipulacea Grown under High-PAR Conditions

    Directory of Open Access Journals (Sweden)

    Yoni Sharon

    2011-01-01

    Full Text Available Since potentially harmful ultraviolet radiation (UVR, 280–400 nm and high photosynthetically active radiation (PAR, 400–700 nm are present in the shallow waters of the Gulf of Aqaba where part of the seagrass Halophila stipulacea's population thrives, we examined the effects of high PAR with and without UVR on its photosynthesis and midday chloroplast “clumping phenomenon” (Sharon and Beer 2008. It was found that midday clumping occurred only under high PAR in the presence of UVR, which resulted in a 44% reduction in the absorption cross section (or absorption factor, AF of the leaves and, accordingly, a parallel lowering of midday electron transport rates (ETR. In addition, UVR had a direct effect on the photosynthetic apparatus by lowering quantum yields and, thus, ETRs, while pigment relations remained unaltered. We conclude that the potentially harmful effects of UVR and high PAR on the photosynthetic apparatus of Halophila stipulacea are mitigated by their activation of chloroplast clumping, which functions as a means of protecting most chloroplasts from high irradiances, including UVR.

  1. 49 CFR 385.315 - Where will the safety audit be conducted?

    Science.gov (United States)

    2010-10-01

    ... SAFETY FITNESS PROCEDURES New Entrant Safety Assurance Program § 385.315 Where will the safety audit be conducted? The safety audit will generally be conducted at the new entrant's business premises. ... 49 Transportation 5 2010-10-01 2010-10-01 false Where will the safety audit be conducted? 385.315...

  2. Animal model for evaluation of topical photoprotection against ultraviolet A (320-380 nm) radiation

    International Nuclear Information System (INIS)

    Chew, S.; DeLeo, V.A.; Harber, L.C.

    1987-01-01

    Recent studies reporting UVA (ultraviolet A radiation 320-380 nm) as an integral part of the cumulative sun-induced damage in human skin have prompted an interest in developing effective UVA photoprotective agents. The development of such compounds has been impeded by the absence of a clinically relevant animal model for evaluating their efficacy. This report describes the development and use of such a laboratory animal system. Selected concentrations of oxybenzone (2-hydroxy-4-methoxybenzophenone) in vehicle (0.1% to 6%) or vehicle alone were applied to the depilated dorsal skin of 30 Hartley strain female albino guinea pigs. The skin was irradiated with solar simulated UVA from a xenon light source. Acute radiation-induced damage was assayed by erythema grading and inhibition of [ 3 H]thymidine incorporation into epidermal DNA. Data from erythema grading studies indicated that a significant degree of photoprotection was achieved with 6%, 3%, and 1% solutions of benzophenone compared with the control vehicle; the 6% solution was significantly more photoprotective than the 3% and 1% solutions. A 6% solution afforded significant photoprotection when assayed by [ 3 H]thymidine incorporation

  3. 34 CFR 280.1 - What is the Magnet Schools Assistance Program?

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false What is the Magnet Schools Assistance Program? 280.1... SECONDARY EDUCATION, DEPARTMENT OF EDUCATION MAGNET SCHOOLS ASSISTANCE PROGRAM General § 280.1 What is the Magnet Schools Assistance Program? The Magnet Schools Assistance Program provides grants to eligible...

  4. Thermoluminescent behavior of diamond thin films exposed to ultraviolet radiation

    International Nuclear Information System (INIS)

    Barboza F, M.; Gastelum, S.; Melendrez, R.; Chernov, V.; Bernal, R.; Cruz V, C.; Brown, F.

    2002-01-01

    In this work the thermoluminescent properties of diamond thin films are discussed which are grown up through the chemical vapor method exposed to ultraviolet radiation of 200-280 nm. The films with thickness 3, 6, 9, 12, 180 and 500 microns were grown up using a precursor gas formed of H 2 -CH 4 -CO excited through microwave energy or hot filament.The structure and morphology of the films were examined through scanning electron microscopy, indicating the formation of different diamond polycrystal structures which depend on the type of heating of the precursor gas used as well as the film dimensions. In general, the brilliance curve depends on the sample and the wavelength of the irradiation ultraviolet light, however it presents clearly thermoluminescence bands in 148, 160, 272, 304, 320 and 324 C degrees. The maximum of the thermoluminescence efficiency is obtained for the case of sample exposure with light of 214 nm. The sample of 500 microns is what exhibits greater thermoluminescent efficiency of those studied samples. The thermoluminescent behavior in function of radiation dose presents regions of linearity and supra linearity for higher and small doses respectively. The disappearance of the thermoluminescent signal depends on the characteristics of the film and it can reach until a 30 % of loss before to reach the stability. (Author)

  5. 32 CFR 37.315 - What are the advantages of using a fixed-support TIA?

    Science.gov (United States)

    2010-07-01

    ... TIA? 37.315 Section 37.315 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE...-Support Technology Investment Agreements § 37.315 What are the advantages of using a fixed-support TIA? In situations where the use of fixed-support TIAs is permissible (see §§ 37.305 and 37.310), their use may...

  6. Colour centres in LiF for measurement of abssorbed doses up to 100 MGy

    International Nuclear Information System (INIS)

    McLaughlin, W.L.

    1996-01-01

    Radiation damage studies on electronic components, polymers, composites, ceramics, metals and insulating materials exposed to very large doses of ionising photons and particles (i.e. electrons, protons, and neutrons) require reproducible and accurate passive dosimetry. Absorbed doses in the range 10 2 -2 x 10 6 Gy have previously been measured with optical quality, undoped LiF by spectrophotometry of radiation-induced absorption bands of stable colour centres. These include the relatively stable F centre (247 nm), M centre (443 nm), R 1 centre (315 nm), R 2 centre (374 nm), and N 2 centre (547 nm). It is now possible to extend this range to 10 8 Gy by spectrophotometry of the N 1 centre (517 nm) and an 'X' centre (785 nm). These dosemeters can be used from cryogenic (4 K) to relatively high radiation temperatures (up to 500 K). The radiation-induced coloration can be bleached for re-use of the dosemeters by a two hour thermal annealing treatment at 830 K. (Author)

  7. Lethal effect of short-wave (254 nm) UV-radiation on cells of Chlamidomonas reinhardii strains with different carotenoid content

    International Nuclear Information System (INIS)

    Kamchatova, I.E.; Chunaev, A.S.; Bronnikov, V.A.

    1987-01-01

    In experiments on related Chlamidomonas reinhardii strains of similar mating type a study was made of sensitivity of cells with different carotenoid content to UV-radiation of 254 nm. Mutants having a lower, as opposed to the wild type strain, content of carotenoids exhibited an increased radiosensitivity. A carotenoid-free mutant was found to possess a higher sensitivity to UV-radiation which was typical of the strain with the impaired excision repair system. The studied subclone of the UV-radiosensitive strain CC-888 was unable to photoreactivate the UV-induced damages which was typical of the wild-type strain. The content of carotenoids in cells of this subnuclone exceeded that in cells of mutants with the reduced pigmentation

  8. Fabrication of biosynthetic vascular prostheses by 193-nm excimer laser radiation

    Science.gov (United States)

    Husinsky, Wolfgang; Csek, Ch.; Bartel, A.; Grabenwoeger, M.; Fitzal, F.; Wolner, Ernst

    1998-05-01

    This study was undertaken to investigate the feasibility of transmural capillary ingrowth into the inner surface of biosynthetic vascular prostheses (OmniflowTM) through perforations created by an excimer-laser, thus inducing an endothelial cell coverage. The biosynthetic vascular prostheses (10 cm length, 6 mm (phi) ) were perforated with an excimer laser ((phi) of the holes 50 - 100 micrometer, distance 4 mm) and implanted into the carotid arteries of 8 sheep. The laser tissue interaction process of 193 nm radiation ensures minimal thermal damage to the prostheses. They were compared to untreated OmniflowTM prostheses implanted at the contralateral side. Three months after implantation the prostheses were explanted and evaluated by gross morphology, histological examination and scanning electron microscopy. Scanning electron microscopy showed endothelial cells in the midgraft portion of all perforated prostheses, whereas collagen fibers, fibrin meshwork and activated platelets formed the inner layer in 6 out of 8 untreated OmniflowTM prostheses. It can be concluded, that spontaneous endothelialization of biosynthetic vascular prostheses can be achieved by transmural capillary ingrowth through perforations in the wall of the prostheses in an experimental sheep model.

  9. Animal and human responses to UVA and UVB

    International Nuclear Information System (INIS)

    Saunders, R.; Cridland, N.; Kowalczuk, C.

    1997-12-01

    Ultraviolet radiation (UVR) comprises the most energetic region of the optical radiation spectrum and is able to induce photochemical changes in the superficial tissues of animals and people which can lead to various acute or chronic adverse health effects. The evidence concerning experimental studies of animals and, where available, volunteers of the effects of occupationally relevant wavelengths (principally UVB, 280-315 rim, and UVA, 315-400 nm) has been reviewed. Experimental studies on animals indicate that exposure to UVR elicits transient (acute) and long-lasting (chronic) effects in the skin and the eye, the severity of which increases in proportion to the exposure. Transient responses have also been investigated in human volunteers and these include adaptive changes such as immediate pigment darkening, melanogenesis and epidermal hyperplasia, and inflammatory responses such as erythema in the skin and keratitis and conjunctivitis in the eye. Irreversible, long-lasting changes also occur following exposure; these include photoageing of the skin, and the development of cataracts in the lens of the eye. Animal studies show that UVR can act either as a complete carcinogen, capable of inducing tumours when applied by itself, or as a co-carcinogen acting in combination with tumour initiators and promoters. The interaction of UVR with the immune system is complex. Exposure to UVR affects the immune system, depressing certain types of cell-mediated antigen-specific responses. Variable immunosuppressive effects have also been reported in humans. In addition, exogenous chemical sensitisers can initiate phototoxic or photoallergic responses in humans and animals; these can precede the development of more persistent idiopathic photodermatoses in which the sensitiser may be an endogenous chemical or antigen. Recommendations for further research are made. (author)

  10. 41 CFR 102-117.280 - What aspects of the TSP's performance are important to measure?

    Science.gov (United States)

    2010-07-01

    ...'s performance are important to measure? 102-117.280 Section 102-117.280 Public Contracts and... § 102-117.280 What aspects of the TSP's performance are important to measure? Important TSP performance...) Percentage of customer satisfaction reports on carrier performance. ...

  11. Sex-dependent effects of ultraviolet radiation on the marine amphipod Ampithoe valida (Ampithoidae).

    Science.gov (United States)

    Valiñas, Macarena S; Helbling, E Walter

    2015-06-01

    The combined effects of solar radiation and diet on the marine amphipod Ampithoe valida were investigated exposing individuals to two solar radiation treatments: PAB (>280 nm, PAR+UV-A+UV-B) and P (>400 nm, only PAR), and three diets: poor (Ulva rigida) and rich (Porphyra columbina) in UV-absorbing compounds (UVAC), and mixed diet: (U. rigida+P. columbina). Females of A. valida showed higher food consumption rates when diets contained P. columbina, and preferred this macroalgae rather than U. rigida, resulting in a higher content of UVAC in their bodies. Moreover, the content of UVAC increased in the PAB treatment, thus suggesting the existence of a mechanism to accumulate these compounds under UVR. Although UVR affected the survival, the highest mortality rates were found in those females fed with poor-UVAC diets, which evidence that UVAC provided partial protection against UVR. Males preferred mixed diet, and did not show preference for any particular macroalgae. No differences in mortality were observed between radiation treatments, indicating that UVR did not affect the survival of males, independently if they accumulated UVAC or not. The vulnerability of females to UVR would be partially determined by the type of food consumed, which in turn would be closely related to the macroalgae composition of the intertidal they inhabiting. These effects could be even more pronounced under a global change scenario. Copyright © 2015 Elsevier B.V. All rights reserved.

  12. 48 CFR 315.371 - Contract preparation and award.

    Science.gov (United States)

    2010-10-01

    ... CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Source Selection 315.371 Contract... the contract until the finance office certifies that the funds are available for obligation. ...

  13. 14 CFR 61.315 - What are the privileges and limits of my sport pilot certificate?

    Science.gov (United States)

    2010-01-01

    ... sport pilot certificate? 61.315 Section 61.315 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... INSTRUCTORS Sport Pilots § 61.315 What are the privileges and limits of my sport pilot certificate? (a) If you hold a sport pilot certificate you may act as pilot in command of a light-sport aircraft, except as...

  14. Visible optical radiation generates bactericidal effect applicable for inactivation of health care associated germs demonstrated by inactivation of E. coli and B. subtilis using 405-nm and 460-nm light emitting diodes

    Science.gov (United States)

    Hönes, Katharina; Stangl, Felix; Sift, Michael; Hessling, Martin

    2015-07-01

    The Ulm University of Applied Sciences is investigating a technique using visible optical radiation (405 nm and 460 nm) to inactivate health-hazardous bacteria in water. A conceivable application could be point-of-use disinfection implementations in developing countries for safe drinking water supply. Another possible application field could be to provide sterile water in medical institutions like hospitals or dental surgeries where contaminated pipework or long-term disuse often results in higher germ concentrations. Optical radiation for disinfection is presently mostly used in UV wavelength ranges but the possibility of bacterial inactivation with visible light was so far generally disregarded. One of the advantages of visible light is, that instead of mercury arc lamps, light emitting diodes could be used, which are commercially available and therefore cost-efficient concerning the visible light spectrum. Furthermore they inherit a considerable longer life span than UV-C LEDs and are non-hazardous in contrast to mercury arc lamps. Above all there are specific germs, like Bacillus subtilis, which show an inactivation resistance to UV-C wavelengths. Due to the totally different deactivation mechanism even higher disinfection rates are reached, compared to Escherichia coli as a standard laboratory germ. By 460 nm a reduction of three log-levels appeared with Bacillus subtilis and a half log-level with Escherichia coli both at a dose of about 300 J/cm². By the more efficient wavelength of 405 nm four and a half log-levels are reached with Bacillus subtilis and one and a half log-level with Escherichia coli also both at a dose of about 300 J/cm². In addition the employed optical setup, which delivered a homogeneous illumination and skirts the need of a stirring technique to compensate irregularities, was an important improvement compared to previous published setups. Evaluated by optical simulation in ZEMAX® the designed optical element provided proven

  15. A long term study of the relations between erythemal UV-B irradiance, total ozone column, and aerosol optical depth at central Argentina

    Science.gov (United States)

    Palancar, Gustavo G.; Olcese, Luis E.; Achad, Mariana; López, María Laura; Toselli, Beatriz M.

    2017-09-01

    Global ultraviolet-B irradiance (UV-B, 280-315 nm) measurements made at the campus of the University of Córdoba, Argentina were analyzed to quantify the effects of ozone and aerosols on surface UV-B erythemal irradiance (UVER). The measurements have been carried out with a YES Pyranometer during the period 2000-2013. The effect of ozone and aerosols has been quantified by means of the Radiation Amplification Factor (RAF) and by an aerosol factor (AF, analogous to RAF), respectively. The overall mean RAF under cloudless conditions was (1.2 ± 0.3) %, ranging from 0.67 to 2.10% depending on solar zenith angle (SZA) and on Aerosol Optical Depth (AOD). The RAF increased with the SZA with a clear trend. Similarly, the aerosol effect under almost-constant ozone and SZA showed that, on average, a 1% increase in AOD forced a decrease of (0.15 ± 0.04) % in the UVER, with a range of 0.06 to 0.27 and no defined trend as a function of the SZA. To analyze the effect of absorbing aerosols, an effective single scattering albedo (SSA) was determined by comparing the experimental UVER with calculations carried out with the TUV radiative transfer model.

  16. Multi-directional radiation detector using photographic film

    International Nuclear Information System (INIS)

    Junet, L K; Majid, Z A Abdul; Sapuan, A H; Sayed, I S; Pauzi, N F

    2014-01-01

    Ionising radiation has always been part of our surrounding and people are continuously exposed to it. Ionising radiation is harmful to human health, thus it is vital to monitor the radiation. To monitor radiation, there are three main points that should be observed cautiously, which are energy, quantity, and direction of the radiation sources. A three dimensional (3D) dosimeter is an example of a radiation detector that provide these three main points. This dosimeter is able to record the radiation dose distribution in 3D. Applying the concept of dose detection distribution, study has been done to design a multi-directional radiation detector of different filter thicknesses. This is obtained by designing a cylinder shaped aluminum filter with several layers of different thickness. Black and white photographic material is used as a radiation-sensitive material and a PVC material has been used as the enclosure. The device is then exposed to a radiation source with different exposure factors. For exposure factor 70 kVp, 16 mAs; the results have shown that optical density (OD) value at 135° is 1.86 higher compared with an OD value at 315° which is 0.71 as the 135° area received more radiation compare to 315° region. Furthermore, with an evidence of different angle of film give different value of OD shows that this device has a multidirectional ability. Materials used to develop this device are widely available in the market, thus reducing the cost of development and making it suitable for commercialisation

  17. Epidermal transmittance and phenolic composition in leaves of atrazine-tolerant and atrazine-sensitive cultivars of Brassica napus grown under enhanced UV-B radiation

    International Nuclear Information System (INIS)

    Olsson, L.C.; Veit, M.; Bornman, J.F.

    1999-01-01

    Experiments were conducted on the atrazine-tolerant mutant Stallion and the atrazine-sensitive cv. Paroll of Brassica napus L., which were grown under either visible light or with the addition of UV-B radiation (280–320 nm) for 15 days. The mutant has been shown to be sensitive to high levels of visible light as compared to the atrazine-sensitive cultivar and therefore we wished to determine plant response to UV-B radiation with respect to potential pigment changes, certain anatomical features, radiation penetration and partial photosynthesis. With regard to pigment changes, we were particularly interested in whether the compositional shift in flavonol pigments under enhanced UV-B radiation, previously suggested to favour increased antioxidant activity, is confined to the adaxial epidermis, which generally receives most UV-B radiation or whether the pigment shift is also inducible in the abaxial epidermis.As was to be expected, the penetration of UV-B radiation (310 nm) was lower in the UV-B-exposed plants, which was correlated with an increased amount of UV-screening pigments in the adaxial and abaxial epidermal layers. The main flavonoid glycosides showed the largest shift from kaempferol to quercetin as aglycone moiety in the adaxial epidermal layer. However, in the abaxial epidermal layer the hydroxycinnamic acid (HCA) derivatives and kaempferol glycosides were predominant. Penetration of 430 nm light was higher after UV-B exposure, and probably contributed to the fact that photosynthetic efficiency of photosystem II was unchanged or higher after UV-B exposure. UV-B radiation decreased leaf area in the atrazine-tolerant mutant only. Both cultivars showed an increased leaf thickness after UV-B exposure due to cell elongation mainly of the palisade tissue. This was especially evident in the mutant

  18. Photosensitivity mechanism of undoped poly(methyl methacrylate) under UV radiation at 325 nm and its spatial resolution limit

    DEFF Research Database (Denmark)

    Sáez-Rodríguez, D.; Nielsen, Kristian; Bang, Ole

    2014-01-01

    that increasing strain during photo-inscription leads to an increased photosensitivity, which is evidence of photodegradation. Likewise, refractive index change in the fiber was measured to be positive, which provides evidence for further polymerization of the material. Finally, we relate the data obtained......In this Letter, we provide evidence suggesting that the main photosensitive mechanism of an undoped poly(methyl methacrylate)-based microstructured optical fiber under UV radiation at 325 nm is a competitive process of both photodegradation and polymerization. We found experimentally...

  19. 9 CFR 3.15 - Primary conveyances (motor vehicle, rail, air, and marine).

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Primary conveyances (motor vehicle, rail, air, and marine). 3.15 Section 3.15 Animals and Animal Products ANIMAL AND PLANT HEALTH... conveyances (motor vehicle, rail, air, and marine). (a) The animal cargo space of primary conveyances used to...

  20. 308nm Excimer Laser in Dermatology

    Science.gov (United States)

    Mehraban, Shadi

    2014-01-01

    308nm xenon-chloride excimer laser, a novel mode of phototherapy, is an ultraviolet B radiation system consisting of a noble gas and halide. The aim of this systematic review was to investigate the literature and summarize all the experiments, clinical trials and case reports on 308-nm excimer laser in dermatological disorders. 308-nm excimer laser has currently a verified efficacy in treating skin conditions such as vitiligo, psoriasis, atopic dermatitis, alopecia areata, allergic rhinitis, folliculitis, granuloma annulare, lichen planus, mycosis fungoides, palmoplantar pustulosis, pityriasis alba, CD30+ lympho proliferative disorder, leukoderma, prurigo nodularis, localized scleroderma and genital lichen sclerosus. Although the 308-nm excimer laser appears to act as a promising treatment modality in dermatology, further large-scale studies should be undertaken in order to fully affirm its safety profile considering the potential risk, however minimal, of malignancy, it may impose. PMID:25606333

  1. 20 CFR 655.315 - State plans.

    Science.gov (United States)

    2010-04-01

    ... other health professionals to become nurses, such as: setting up home study programs with State... monetary grants or long-term loans to persons preparing to become nurses. (6) Steps may be taken to... Nurses § 655.315 State plans. A State may submit an annual plan for the recruitment and retention of U.S...

  2. Atmospheric radionuclide transport model with radon postprocessor and SBG module. Model description version 2.8.0; ARTM. Atmosphaerisches Radionuklid-Transport-Modell mit Radon Postprozessor und SBG-Modul. Modellbeschreibung zu Version 2.8.0

    Energy Technology Data Exchange (ETDEWEB)

    Richter, Cornelia; Sogalla, Martin; Thielen, Harald; Martens, Reinhard

    2015-04-20

    The study on the atmospheric radionuclide transport model with radon postprocessor and SBG module (model description version 2.8.0) covers the following issues: determination of emissions, radioactive decay, atmospheric dispersion calculation for radioactive gases, atmospheric dispersion calculation for radioactive dusts, determination of the gamma cloud radiation (gamma submersion), terrain roughness, effective source height, calculation area and model points, geographic reference systems and coordinate transformations, meteorological data, use of invalid meteorological data sets, consideration of statistical uncertainties, consideration of housings, consideration of bumpiness, consideration of terrain roughness, use of frequency distributions of the hourly dispersion situation, consideration of the vegetation period (summer), the radon post processor radon.exe, the SBG module, modeling of wind fields, shading settings.

  3. Mathematical simulation of the amplification of 1790-nm laser radiation in a nuclear-excited He - Ar plasma containing nanoclusters of uranium compounds

    Science.gov (United States)

    Kosarev, V. A.; Kuznetsova, E. E.

    2014-02-01

    The possibility of applying dusty active media in nuclearpumped lasers has been considered. The amplification of 1790-nm radiation in a nuclear-excited dusty He - Ar plasma is studied by mathematical simulation. The influence of nanoclusters on the component composition of the medium and the kinetics of the processes occurring in it is analysed using a specially developed kinetic model, including 72 components and more than 400 reactions. An analysis of the results indicates that amplification can in principle be implemented in an active laser He - Ar medium containing 10-nm nanoclusters of metallic uranium and uranium dioxide.

  4. Ultraviolet radiation

    International Nuclear Information System (INIS)

    Faber, M.

    1982-01-01

    Penetration of the human body by shorter-wavelength UV is restricted to the epidermis. Penetration is somewhat deeper at longer wavelengths and in non-pigmented subjects, where there is some penetration into the dermis, especially at wavelengths greater than 300 nm. The same is true for the eye. Most of the UV will be absorbed by the cornea. The lens and the tissues in the anterior part of the eye may, however, be exposed to UV at wavelengths above 295 nm. The final absorption takes place in the lens, and the retina can be exposed only under special circumstances. The penetration of different wavelengths into the eye is given in Table 1. Some doubt exists, however as to the high transmission given for the vitreous humour at the longer wavelengths. The absorption of UV depends on the wavelength. The absorption spectrum describes this relationship. Proteins and nucleic acids are the most important biological absorbers. Nucleic acids have their main absorption peak close to 265 nm, due to the pyrimidine structure. The aromatic amino-acids are the absorbing sites in protein, with tyrosine at 275 nm and tryptophane at 280 nm

  5. Protection against ultraviolet-B radiation-induced local and systemic suppression of contact hypersensitivity and edema responses in C3H/HeN mice by green tea polyphenols

    International Nuclear Information System (INIS)

    Katiyar, S.K.; Elmets, C.A.; Agarwal, Rajesh; Mukhtar, Hasan

    1995-01-01

    Exposure of skin to UV radiation can cause diverse biological effects, including induction of inflammation, alteration in cutaneous immune cells and impairment of contact hypersensitivity (CHS) responses. Our laboratory has demonstrated that oral feeding as well as topical application of a polyphenolic fraction isolated from green tea (GTP) affords protection against the carcinogenic effects of UVB (280-320 nm) radiation. In this study, we investigated whether GTP could protect against UVB-induced immunosuppression and cutaneous inflammatory responses in C3H mice. Immunosuppression was assessed by contact sensitization with 2,4-dinitrofluorobenzene applied to UVB-irradiated skin (local suppression) or to a distant site (systemic suppression), while double skin-fold swelling was used as the measure of UVB-induced inflammation. (author)

  6. 33 CFR 127.315 - Preliminary transfer inspection.

    Science.gov (United States)

    2010-07-01

    ... (CONTINUED) WATERFRONT FACILITIES WATERFRONT FACILITIES HANDLING LIQUEFIED NATURAL GAS AND LIQUEFIED HAZARDOUS GAS Waterfront Facilities Handling Liquefied Natural Gas Operations § 127.315 Preliminary transfer... parts; (b) For each of the vessel's cargo tanks from which cargo will be transferred, note the pressure...

  7. Impacts of varying light regimes on phycobiliproteins of Nostoc sp. HKAR-2 and Nostoc sp. HKAR-11 isolated from diverse habitats.

    Science.gov (United States)

    Kannaujiya, Vinod K; Sinha, Rajeshwar P

    2015-11-01

    The adaptability of cyanobacteria in diverse habitats is an important factor to withstand harsh conditions. In the present investigation, the impacts of photosynthetically active radiation (PAR; 400-700 nm), ultraviolet-B (UV-B; 280-315 nm), and PAR + UV-B radiations on two cyanobacteria viz., Nostoc sp. HKAR-2 and Nostoc sp. HKAR-11 inhabiting diverse habitats such as hot springs and rice fields, respectively, were studied. Cell viability was about 14 % in Nostoc sp. HKAR-2 and Nostoc sp. HKAR-11 after 48 h of UV-B exposure. PAR had negligible negative impact on the survival of both cyanobacteria. The continuous exposure of UV-B and PAR + UV-B showed rapid uncoupling, bleaching, fragmentation, and degradation in both phycocyanin (C-PC) and phycoerythrin (C-PE) subunits of phycobiliproteins (PBPs). Remarkable bleaching effect of C-PE and C-PC was not only observed with UV-B or PAR + UV-B radiation, but longer period (24-48 h) of exposure with PAR alone also showed noticeable negative impact. The C-PE and C-PC subunits of the rice field isolate Nostoc sp. HKAR-11 were severely damaged in comparison to the hot spring isolate Nostoc sp. HKAR-2 with rapid wavelength shifting toward shorter wavelengths denoting the bleaching of both the accessory light harvesting pigments. The results indicate that PBPs of the hot spring isolate Nostoc sp. HKAR-2 were more stable under various light regimes in comparison to the rice field isolate Nostoc sp. HKAR-11 that could serve as a good source of valuable pigments to be used in various biomedical and biotechnological applications.

  8. Evidence for Radiative Recombination of O+ Ions as a Significant Source of O 844.6 nm Emission Excitation

    Science.gov (United States)

    Waldrop, L.; Kerr, R. B.; Huang, Y.

    2018-04-01

    Photoelectron (PE) impact on ground-state O(3P) atoms is well known as a major source of twilight 844.6 nm emission in the midlatitude thermosphere. Knowledge of the PE flux can be used to infer thermospheric oxygen density, [O], from photometric measurements of 844.6 nm airglow, provided that PE impact is the dominant process generating the observed emission. During several spring observational campaigns at Arecibo Observatory, however, we have observed significant 844.6 nm emission throughout the night, which is unlikely to arise from PE impact excitation which requires solar illumination of either the local or geomagnetically conjugate thermosphere. Here we show that radiative recombination (RR) of O+ ions is likely responsible for the observed nighttime emission, based on model predictions of electron and O+ ion density and temperature by the Incoherent Scatter Radar Ionosphere Model. The calculated emission brightness produced by O + RR exhibits good agreement with the airglow data, in that both decay approximately monotonically throughout the night at similar rates. We conclude that the conventional assumption of a pure PE impact source is most likely to be invalid during dusk twilight, when RR-generated emission is most significant. Estimation of [O] from measurements of 844.6 nm emission demands isolation of the PE impact source via coincident estimation of the RR source, and the effective cross section for RR-generated emission is found here to be consistent with optically thin conditions.

  9. PILOT STUDY: Report on the CCPR Pilot Comparison: Spectral Responsivity 10 nm to 20 nm

    Science.gov (United States)

    Scholze, Frank; Vest, Robert; Saito, Terubumi

    2010-01-01

    The CCPR Pilot Comparison on spectral responsivity in the 10 nm to 20 nm spectral range was carried out within the framework of the CIPM Mutual Recognition Arrangement by three laboratories: PTB (Germany), NIST (USA), and NMIJ/AIST (Japan) with PTB acting as the central and reporting laboratory. All participating laboratories used monochromatized synchrotron radiation. PTB and NIST used a cryogenic radiometer as the primary standard detector and NMIJ, an ionization chamber with extrapolation by a wavelength-independent detector. The aim of the pilot comparison was to check the accuracy of the radiometric scale of spectral responsivity in the short wavelength EUV spectral range which has recently gained in technological importance. The wavelengths of measurement were from 11.5 nm to 20 nm in 0.5 nm steps and additionally 12.2 nm. The comparison was carried out through the calibration of a group of transfer standard detectors. Two sets of three diodes of types AXUV and SXUV from International Radiation Detectors, Inc. were used for the comparison. The comparison had the form of a star comparison: Pilot-lab A-pilot-lab B-pilot, PTB acting as the pilot laboratory. All results were communicated directly to the pilot laboratory. The report describes in detail the measurements made at PTB and summarizes the reports submitted by the participants. Measurements carried out by the pilot laboratory before and after the circulation of the detectors proved that the stability of the detectors was sufficient for the comparison. For the type AXUV detectors, however, changes in their responsivity contributed to the uncertainty of the comparison. Measurement results from participants and their associated uncertainties were analyzed in this report according to the Guidelines for CCPR Comparison Report Preparation. The uncertainty contributions were separated, as to whether they are wavelength dependent or not. All bilateral DoE are well within the respective k = 2 expanded uncertainty

  10. Microstructural, Raman and XPS properties of single-crystalline Bi3.15Nd0.85Ti3O12 nanorods

    International Nuclear Information System (INIS)

    Hu Zhenglong; Gu Haoshuang; Hu Yongming; Zou Yanan; Zhou Di

    2009-01-01

    Bi 3.15 Nd 0.85 Ti 3 O 12 (BNT) nanorods were successfully synthesized first time by hydrothermal method. The nanorods are uniform along their length, and are composed of single-crystalline BNT with orthorhombic structure. The diameters of BNT nanorods are about 30-120 nm and growth along the [1 0 4] direction, which are promising candidate for nanoscale ferroelectric sensors. Ten Raman active modes were observed for orthorhombic phase BNT nanorods, which are overdamped and highly shifted compare to that of Bi 4 Ti 3 O 12 (BIT) powders. The chemical composition of the samples and the valence states of elements were determined by X-ray photoelectron spectroscopy

  11. Effects of ultraviolet radiation on the lower levels of the planktonic food web in Antarctica

    International Nuclear Information System (INIS)

    Ferreyra, Gustavo A.; Schloss, Irene; Tosonotto, Gabriela; Calvino, Eduardo; Rodriguez, Silvia; Cantoni, Leonardo; Gonzalez, Oscar; Ulrich, Alejandro; Hernando, Marcelo; Hernandez, Edgardo; Oyarbide, Fabricio

    2004-01-01

    Full text: Most of the studies that investigated the effects of ultraviolet radiation (UVR, 280-400 NM) on the first levels of the marine food web used experimental approaches (in situ incubations, micro and mesocosms). However, research on the responses to UVR of the micro community in their natural environment is scarce. A time series study including most of the oceanographic parameters described as controlling bacteria and phytoplankton dynamics was carried out (PAR, tidal mixing, turbulent mixing by winds and currents, nutrient stress). In this case, however, the effects of ultraviolet A and B (UVB, 280-320 nm and UVA, 320-400 nm, respectively) were added as forcing parameters. Fieldwork was done in the vicinity of Melchior Station (64 degrees 20' S, 62 degrees 59' W, Observatory Island). It involved the automated measurement of physical variables (currents, tides and meteorological data), as well as discrete sampling of physical (salinity, temperature), chemical (macro nutrients) and biological variables (bacterial and phytoplankton abundance and production, PSI I system, photo protective compounds). Sub-surface sampling (0.5 m depth) was conducted with 5 L Niskin bottles at a fixed station (sampling every 6/12 h centered at local noon during the whole study period), and vertical profiles at 6 fixed depths (0, 5, 10, 20, 30 and 50 m) were done every four days. The whole study lasted for one month, from February 11 to March 12 2002. Average upper mixed layer (UML) was around 20 m and the depth of the euphotic zone (1% of incident radiation) for UVB and UVA was respectively 17 and 32 m, suggesting a strong influence of UVR on cells within the UML. PSII activity showed a significant inverse correlation with UVB, phased with irradiance oscillations. Bacterio plankton and phytoplankton biomass and production of both presented a similar response, but minimum values were lagged by 4-6 h from UVR maxima. Mycosporin like aminoacids (MAA's) were also phased and directly

  12. Fabrication and characterization of UV-emitting nanoparticles as novel radiation sensitizers targeting hypoxic tumor cells

    Science.gov (United States)

    Squillante, Michael R.; Jüstel, Thomas; Anderson, R. Rox; Brecher, Charles; Chartier, Daniel; Christian, James F.; Cicchetti, Nicholas; Espinoza, Sara; McAdams, Daniel R.; Müller, Matthias; Tornifoglio, Brooke; Wang, Yimin; Purschke, Martin

    2018-06-01

    Radiation therapy is one of the primary therapeutic techniques for treating cancer, administered to nearly two-thirds of all cancer patients. Although largely effective in killing cancer cells, radiation therapy, like other forms of cancer treatment, has difficulty dealing with hypoxic regions within solid tumors. The incomplete killing of cancer cells can lead to recurrence and relapse. The research presented here is investigating the enhancement of the efficacy of radiation therapy by using scintillating nanoparticles that emit UV photons. UV photons, with wavelengths between 230 nm and 280 nm, are able to inactivate cells due to their direct interaction with DNA, causing a variety of forms of damage. UV-emitting nanoparticles will enhance the treatment in two ways: first by generating UV photons in the immediate vicinity of cancer cells, leading to direct and oxygen-independent DNA damage, and second by down-converting the applied higher energy X-rays into softer X-rays and particles that are more efficiently absorbed in the targeted tumor region. The end result will be nanoparticles with a higher efficacy in the treatment of hypoxic cells in the tumor, filling an important, unmet clinical need. Our preliminary experiments show an increase in cell death using scintillating LuPO4:Pr nanoparticles over that achieved by the primary radiation alone. This work describes the fabrication of the nanoparticles, their physical characterization, and the spectroscopic characterization of the UV emission. The work also presents in vitro results that demonstrate an enhanced efficacy of cell killing with x-rays and a low unspecific toxicity of the nanoparticles.

  13. Identification of actin binding protein, ABP-280, as a binding partner of human Lnk adaptor protein.

    Science.gov (United States)

    He, X; Li, Y; Schembri-King, J; Jakes, S; Hayashi, J

    2000-08-01

    Human Lnk (hLnk) is an adaptor protein with multiple functional domains that regulates T cell activation signaling. In order to identify cellular Lnk binding partners, a yeast two-hybrid screening of human spleen cDNA library was carried out using human hLnk as bait. A polypeptide sequence identical to the C-terminal segment of the actin binding protein (ABP-280) was identified as a hLnk binding protein. The expressed hLnk and the FLAG tagged C-terminal 673 amino acid residues of ABP-280 or the endogenous ABP-280 in COS-7 cells could be co-immunoprecipitated using antibodies either to hLnk, FLAG or ABP-280, respectively. Furthermore, immunofluorescence confocal microscope showed that hLnk and ABP-280 co-localized at the plasma membrane and at juxtanuclear region of COS-7 cells. In Jurkat cells, the endogenous hLnk also associates with the endogenous ABP-280 indicating that the association of these two proteins is physiological. The interacting domains of both proteins were mapped using yeast two-hybrid assays. Our results indicate that hLnk binds to the residues 2006-2454 (repeats 19-23C) of ABP-280. The domain in hLnk that associates with ABP-280 was mapped to an interdomain region of 56 amino acids between pleckstrin homology and Src homology 2 domains. These results suggest that hLnk may exert its regulatory role through its association with ABP-280.

  14. 7 CFR 51.315 - Fairly well formed.

    Science.gov (United States)

    2010-01-01

    ... Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946... Standards for Grades of Apples Definitions § 51.315 Fairly well formed. “Fairly well formed” means that the...

  15. 36 CFR 223.280 - Waiver of fees and/or fair market value.

    Science.gov (United States)

    2010-07-01

    ... fees and/or fair market value. The Forest Service waives the collection of fees otherwise required... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Waiver of fees and/or fair market value. 223.280 Section 223.280 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF...

  16. Allogeneic stem cell transplantation for patients harboring T315I BCR-ABL mutated leukemias

    DEFF Research Database (Denmark)

    Nicolini, Franck Emmanuel; Basak, Grzegorz W; Soverini, Simona

    2011-01-01

    T315I(+) Philadelphia chromosome-positive leukemias are inherently resistant to all licensed tyrosine kinase inhibitors, and therapeutic options remain limited. We report the outcome of allogeneic stem cell transplantation in 64 patients with documented BCR-ABL(T315I) mutations. Median follow......) as unfavorable factors. We conclude that allogeneic stem cell transplantation represents a valuable therapeutic tool for eligible patients with BCR-ABL(T315I) mutation, a tool that may or may not be replaced by third-generation tyrosine kinase inhibitors....

  17. The action of NIR (808nm) laser radiation and gold nanorods labeled with IgA and IgG human antibodies on methicillin-resistant and methicillin sensitive strains of Staphylococcus aureus

    Science.gov (United States)

    Tuchina, Elena S.; Petrov, Pavel O.; Ratto, Fulvio; Centi, Sonia; Pini, Roberto; Tuchin, Valery V.

    2015-03-01

    The effect of NIR laser radiation (808 nm) on methicillin-sensitive and methicillin resistant strains of Staphylococcus aureus incubated with gold nanorods is studied. Nanorods having length of 44 (± 4) nm and diameter of 10 (± 3) nm with the absorption maximum in the NIR (800 nm), functionalized with human immunoglobulins IgA and IgG, were synthesized and used in the studies. The killing ability up to 97% of the microorganism populations by using this nanotechnology was shown.

  18. Investigation of the use of Ishiagu Galena Concrete in E-M Radiation Sheilding

    Directory of Open Access Journals (Sweden)

    Gabriel Ndubisi EGWUONWU

    2012-08-01

    Full Text Available Galena samples, collected from Ishiagu, south-eastern Nigeria, were used to make concretes for experimental radiation shielding. The concretes were moulded into cylindrical tablets of various densities in order to ascertain their attenuation capability to some electromagnetic radiations. Blue visible light and gamma-ray (455-500 nm sourced from cobolt-60, were transmitted through the concretes and detected with the aid of Op-Amp and digital Geiger-Muller Counter respectively. The absorption coefficients of the samples of thicknesses in the range of 1.00 mm – 5.00 cm were determined. Results obtained show that a typical Ishiagu galena concrete of about 2.80 g/cm3 has the capacity of shielding visible blue light with about 2.51 mm TVL and 0.81 mm HVL. It also shows that the concrete of similar density can optimally shield gamma radiation with about 5.06 cm TVL and 1.53 cm HVL. The results of the investigation however, suggest the shielding and engineering properties of the galena sourced from Ishiagu. A database of shielding strength for the insitu galena was established hence, can serve as suitable platform for quality and quantity control in radiation shielding technology and can be used in high voltage radiotherapy rooms and nuclear reactors.

  19. Detailed conformation dynamics and activation process of wild type c-Abl and T315I mutant

    Science.gov (United States)

    Yang, Li-Jun; Zhao, Wen-Hua; Liu, Qian

    2014-10-01

    Bcr-Abl is an important target for therapy against chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL). The synergistic effect between myristyl pocket and the ATP pocket has been found. But its detailed information based on molecular level still has not been achieved. In this study, conventional molecular dynamics (CMD) and target molecular dynamics (TMD) simulations were performed to explore the effect of T315I mutation on dynamics and activation process of Abl containing the N-terminal cap (Ncap). The CMD simulation results reveal the increasing flexibility of ATP pocket in kinase domain (KD) after T315I mutation which confirms the disability of ATP-pocket inhibitors to the Abl-T315I mutant. On the contrary, the T315I mutation decreased the flexibility of remote helix αI which suggests the synergistic effect between them. The mobility of farther regions containing Ncap, SH3, SH2 and SH2-KD linker were not affected by T315I mutation. The TMD simulation results show that the activation process of wild type Abl and Abl-T315I mutant experienced global conformation change. Their differences were elucidated by the activation motion of subsegments including A-loop, P-loop and Ncap. Besides, the T315I mutation caused decreasing energy barrier and increasing intermediate number in activation process, which results easier activation process. The TMD and CMD results indicate that a drug targeting only the ATP pocket is not enough to inhibit the Abl-T315I mutant. An effective way to inhibit the abnormal activity of Abl-T315I mutant is to combine the ATP-pocket inhibitors with inhibitors binding at non-ATP pockets mainly related to Ncap, SH2-KD linker and myristyl pocket.

  20. High and Low LET Radiation Differentially Induce Normal Tissue Damage Signals

    International Nuclear Information System (INIS)

    Niemantsverdriet, Maarten; Goethem, Marc-Jan van; Bron, Reinier; Hogewerf, Wytse; Brandenburg, Sytze; Langendijk, Johannes A.; Luijk, Peter van; Coppes, Robert P.

    2012-01-01

    Purpose: Radiotherapy using high linear energy transfer (LET) radiation is aimed at efficiently killing tumor cells while minimizing dose (biological effective) to normal tissues to prevent toxicity. It is well established that high LET radiation results in lower cell survival per absorbed dose than low LET radiation. However, whether various mechanisms involved in the development of normal tissue damage may be regulated differentially is not known. Therefore the aim of this study was to investigate whether two actions related to normal tissue toxicity, p53-induced apoptosis and expression of the profibrotic gene PAI-1 (plasminogen activator inhibitor 1), are differentially induced by high and low LET radiation. Methods and Materials: Cells were irradiated with high LET carbon ions or low LET photons. Cell survival assays were performed, profibrotic PAI-1 expression was monitored by quantitative polymerase chain reaction, and apoptosis was assayed by annexin V staining. Activation of p53 by phosphorylation at serine 315 and serine 37 was monitored by Western blotting. Transfections of plasmids expressing p53 mutated at serines 315 and 37 were used to test the requirement of these residues for apoptosis and expression of PAI-1. Results: As expected, cell survival was lower and induction of apoptosis was higher in high -LET irradiated cells. Interestingly, induction of the profibrotic PAI-1 gene was similar with high and low LET radiation. In agreement with this finding, phosphorylation of p53 at serine 315 involved in PAI-1 expression was similar with high and low LET radiation, whereas phosphorylation of p53 at serine 37, involved in apoptosis induction, was much higher after high LET irradiation. Conclusions: Our results indicate that diverse mechanisms involved in the development of normal tissue damage may be differentially affected by high and low LET radiation. This may have consequences for the development and manifestation of normal tissue damage.

  1. 9 CFR 315.2 - Carcasses and parts passed for cooking; utilization for food purposes after cooking.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Carcasses and parts passed for cooking; utilization for food purposes after cooking. 315.2 Section 315.2 Animals and Animal Products FOOD SAFETY AND... PARTS PASSED FOR COOKING § 315.2 Carcasses and parts passed for cooking; utilization for food purposes...

  2. 46 CFR 280.9 - Special rules for last year of ODS agreement.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Special rules for last year of ODS agreement. 280.9... LINER OPERATORS § 280.9 Special rules for last year of ODS agreement. (a) Reduction in payment of ODS. ODS payable during the last year of any ODS agreement shall be reduced, as provided in paragraph (b...

  3. 40 CFR 280.99 - Letter of credit.

    Science.gov (United States)

    2010-07-01

    ... (UST) Financial Responsibility § 280.99 Letter of credit. (a) An owner or operator may satisfy the... brackets are to be replaced with the relevant information and the brackets deleted: Irrevocable Standby.... We certify that the wording of this letter of credit is identical to the wording specified in 40 CFR...

  4. Mammalian cell biology

    International Nuclear Information System (INIS)

    Anon.

    1976-01-01

    Progress is reported on studies of the molecular biology and functional changes in cultured mammalian cells following exposure to x radiation, uv radiation, fission neutrons, or various chemical environmental pollutants alone or in combinations. Emphasis was placed on the separate and combined effects of polycyclic aromatic hydrocarbons released during combustion of fossil fuels and ionizing and nonionizing radiations. Sun lamps, which emit a continuous spectrum of near ultraviolet light of 290 nm to 315 nm were used for studies of predictive cell killing due to sunlight. Results showed that exposure to uv light (254 nm) may not be adequate to predict effects produced by sunlight. Data are included from studies on single-strand breaks and repair in DNA of cultured hamster cells exposed to uv or nearultraviolet light. The possible interactions of the polycyclic aromatic hydrocarbon 7,12-dimethylbenz(a)-anthracene (DmBA) alone or combined with exposure to x radiation, uv radiation (254 nm) or near ultraviolet simulating sunlight were compared for effects on cell survival

  5. Comparison of UV action spectra for lethality and mutation in Salmonella typhimurium using a broad band source and monochromatic radiations

    International Nuclear Information System (INIS)

    Calkins, John; Selby, Christopher; Enoch, H.G.

    1987-01-01

    The UV-B region (280-320 nm) is thought to be primarily responsible for the mutagenic, lethal, and carcinogenic effects of solar radiation. We have conducted UV-B action spectroscopy for mutagenesis and survival of Ames' Salmonella typhimurium strain TA98 (uvrB, pKM101) using both monochromatic radiation from a dye laser and broader bandwidth radiation emitted from FS-20 sunlamps. A series of optical filters having different transmission cut-offs together with the sunlamp source provided bandwidths having successively less short wavelength components from which a ''broad band'' action spectrum was deduced. The two sets of action spectra differed both qualitatively and quantitatively: in comparison to the monochromatic action spectra, the ''broad band'' spectra showed up to a 200-fold reduced efficiency for both mutation induction and lethality by UV-B wavelengths. These results suggest a large protective effect of the background UV-A and/or visible radiations which were present during the broad spectrum irradiations and which are also present in solar radiation. Additional experiments show that to the extent tested this protective effect is not due to photo-reactivation or irradiance (dose rate) effects. (author)

  6. The effect of UV radiation on photosynthesis in an Antarctic diatom (Thalassiosira sp.): does vertical mixing matter?

    International Nuclear Information System (INIS)

    Hernando, Marcelo P.; Ferreyra, Gustavo A.

    2004-01-01

    Full text: The reduction of the Antarctic stratospheric ozone resulted in significant increases in ultraviolet B radiation (UVBR, 280-320 nm) reaching the surface of the ocean. A series of laboratory and field experiments were conducted at Potter Cove (25 de Mayo Is., South Shetland Is., Antarctica) to study the effects of UVBR on photosynthesis of a typical Antarctic bloom forming diatom (Thalassiosira sp.) in fixed and moving incubations. There were three irradiance treatments: PART (with only photosynthetic active radiation, PAR, 400- 700 nm), UVAT (with PAR and ultraviolet A radiation, UVAR, 320-400 nm) and UVBT (with PAR, UVAR and UVBR). The three treatments were incubated in the field and laboratory with a solar simulator (SOLSI) in fixed frames at 0.5 and 5 m depth (S fix and B fix , respectively), while for the moving incubations were done within 6 h cycles (Mix). Considering the field and laboratory pooled data, results suggest an overall 45-50 % photosynthesis inhibition of S fix incubations in relation with Mix ones. During SOLSI experiments no significant differences were found between irradiance treatments under normal and medium ozone concentrations. Under low ozone conditions, a 40 % reduction in photosynthesis was observed in the UVBT for S fix . In contrast, no significant differences were observed between the irradiance treatments for Mix. Field experiment showed results similar to the laboratory ones, but in this case not only S fix but Mix incubations presented a significant reduction in photosynthesis under low ozone. The differences between laboratory and field experiments are discussed in terms of the relative significance of UVBR dose and dose rate on both types of experiments. (author)

  7. Building blocks for future detectors: Silicon test masses and 1550 nm laser light

    International Nuclear Information System (INIS)

    Schnabel, R; Britzger, M; Burmeister, O; Danzmann, K; Duck, J; Eberle, T; Friedrich, D; Luck, H; Mehmet, M; Steinlechner, S; Willke, B; Brueckner, F; Nawrodt, R

    2010-01-01

    Current interferometric gravitational wave detectors use the combination of quasi-monochromatic, continuous-wave laser light at 1064 nm and fused silica test masses at room temperature. Detectors of the third generation, such as the Einstein-Telescope, will involve a considerable sensitivity increase. The combination of 1550 nm laser radiation and crystalline silicon test masses at low temperatures might be important ingredients in order to achieve the sensitivity goal. Here we compare some properties of the fused silica and silicon test mass materials relevant for decreasing the thermal noise in future detectors as well as the recent technology achievements in the preparation of laser radiation at 1064 nm and 1550 nm relevant for decreasing the quantum noise. We conclude that silicon test masses and 1550 nm laser light have the potential to form the future building blocks of gravitational wave detection.

  8. UV-Induced Cell Death in Plants

    Science.gov (United States)

    Nawkar, Ganesh M.; Maibam, Punyakishore; Park, Jung Hoon; Sahi, Vaidurya Pratap; Lee, Sang Yeol; Kang, Chang Ho

    2013-01-01

    Plants are photosynthetic organisms that depend on sunlight for energy. Plants respond to light through different photoreceptors and show photomorphogenic development. Apart from Photosynthetically Active Radiation (PAR; 400–700 nm), plants are exposed to UV light, which is comprised of UV-C (below 280 nm), UV-B (280–320 nm) and UV-A (320–390 nm). The atmospheric ozone layer protects UV-C radiation from reaching earth while the UVR8 protein acts as a receptor for UV-B radiation. Low levels of UV-B exposure initiate signaling through UVR8 and induce secondary metabolite genes involved in protection against UV while higher dosages are very detrimental to plants. It has also been reported that genes involved in MAPK cascade help the plant in providing tolerance against UV radiation. The important targets of UV radiation in plant cells are DNA, lipids and proteins and also vital processes such as photosynthesis. Recent studies showed that, in response to UV radiation, mitochondria and chloroplasts produce a reactive oxygen species (ROS). Arabidopsis metacaspase-8 (AtMC8) is induced in response to oxidative stress caused by ROS, which acts downstream of the radical induced cell death (AtRCD1) gene making plants vulnerable to cell death. The studies on salicylic and jasmonic acid signaling mutants revealed that SA and JA regulate the ROS level and antagonize ROS mediated cell death. Recently, molecular studies have revealed genes involved in response to UV exposure, with respect to programmed cell death (PCD). PMID:23344059

  9. Mutagenic action of non-ionizing radiations: its implication in radiation protection

    International Nuclear Information System (INIS)

    Madhvanath, U.; Subrahmanyam, P.; Sankaranarayanan, N.; Singh, D.R.

    1977-01-01

    Mutagenic effects of non-ionizing radiations except in the ultraviolet and near ultraviolet region are just not known. Results of the investigation carried out using a sensitive diploid yeast system, are presented. The arginine requiring mutant yeast strain BZ34 reverts to prototrophy following exposure to ionizing radiation. Reversion frequencies were determined following exposure to UV (254 nm), near ultraviolet (313, 353 nm) visible region (480 nm), neodymium laser (1.01 μm) and microwave (2450 MHz) radiations. An Aminco - Bowman Spectrophotofluorimeter was used to obtain wavelengths from UV to visible region. Yeast suspensions (concentration of 10 7 cells/ml) were irradiated to doses ranging from 10 7 to 10 9 erg/cm 3 as determined with potassium ferri-oxalate system. Exposure to laser pulses and microwave radiation ranged up to 45 J/cm 2 and 60 mW-h/cm 2 respectively. Results showed that the reversion induction efficiency decreased by six orders of magnitude from ionizing radiations to ultraviolet for the same absorbed dose and this efficiency has further decreased by a factor of fifteen when the wavelength is increased from 254 nm to 313 nm. Although killing could be effected with laser beams (45 J/cm 2 for 50% survival) no increase in the reversion was observed than the background level. It is concluded that radiation of wavelengths higher than 450 nm up to 12 cm studied is not mutagenic and with sufficient intensities of these radiations only killing of cells is possible due to thermal effects. This finding is compared with other known functional and morphological effects at cellular level due to low-level exposures of non-ionizing radiations

  10. T315 Decreases Acute Myeloid Leukemia Cell Viability through a Combination of Apoptosis Induction and Autophagic Cell Death

    Directory of Open Access Journals (Sweden)

    Chang-Fang Chiu

    2016-08-01

    Full Text Available T315, an integrin-linked kinase (ILK inhibitor, has been shown to suppress the proliferation of breast cancer, stomach cancer and chronic lymphocytic leukemia cells. Here we demonstrate that T315 decreases cell viability of acute myeloid leukemia (AML cell lines (HL-60 and THP-1 and primary leukemia cells from AML patients in a dose-responsive manner. Normal human bone marrow cells are less sensitive than leukemia cells to T315. T315 down regulates protein kinase B (Akt and p-Akt and induces caspase activation, poly-ADP-ribose polymerase (PARP cleavage, apoptosis and autophagy through an ILK-independent manner. Interestingly, pretreatment with autophagy inhibitors rescues cells from apoptosis and concomitant PARP cleavage, which implicates a key role of autophagic cell death in T315-mediated cytotoxicity. T315 also demonstrates efficacy in vivo, suppressing the growth of THP-1 xenograft tumors in athymic nude mice when administered intraperitoneally. This study shows that autophagic cell death and apoptosis cooperatively contribute to the anticancer activity of T315 in AML cells. In conclusion, the complementary roles of apoptotic and autophagic cell death should be considered in the future assessment of the translational value of T315 in AML therapy.

  11. Researchers lack data on trends in UV radiation at Earth's surface

    International Nuclear Information System (INIS)

    Zurer, P.S.

    1993-01-01

    Current anxiety about depletion of stratospheric ozone stems from the expected resulting increase in biologically damaging ultraviolet (UV) radiation at Earth's surface. Atmospheric ozone absorbs sunlight with wavelengths shorter than 320 nm--the highest-energy UV-B wavelengths (280-320 nm) that can damage DNA in living systems. But surprisingly, despite firm evidence the ozone layer is being eroded by chlorine and bromine from man-made compounds, very little information exists on how UV light intensity is changing. Solid data from Antarctica reveal that UV radiation soars under the ozone hole, where fully half of the atmospheric ozone is destroyed each spring. But elsewhere on the globe, where ozone has been thinning at a rate of a few percent per decade, the corresponding trends in UV intensity are not at all clear. In the late 1970s and early 1980s the problem of ozone depletion seemed solved. The US had banned the use of chlorofluorocarbons (CFCs) in aerosols. Model calculations were predicting CFCs would cause only a small loss of ozone by the second half of the 21st century. Costly monitoring of UV radiation commanded little attention. Attitudes began to change with the 1985 discovery of the Antarctic ozone hole. The National Science Foundation (NSF) established UV monitoring stations in the Antarctic in 1988, adding an Alaskan station in 1990. Both the Department of Agriculture (USDA) and the Environmental Protection Agency (EPA) have programs in the works that will eventually place monitoring stations across the US, but it will be many years before researchers have access to the kind of extensive database necessary to reliably evaluation long-term trends in UV intensity

  12. Downhole Upgrading of Orinoco Basin Extra-Heavy Crude Oil Using Hydrogen Donors under Steam Injection Conditions. Effect of the Presence of Iron Nanocatalysts

    Directory of Open Access Journals (Sweden)

    Cesar Ovalles

    2015-03-01

    Full Text Available An extra-heavy crude oil underground upgrading concept and laboratory experiments are presented which involve the addition of a hydrogen donor (tetralin to an Orinoco Basin extra-heavy crude oil under steam injection conditions (280315 °C and residence times of at least 24-h. Three iron-containing nanocatalysts (20 nm, 60 nm and 90 nm were used and the results showed increases of up to 8° in API gravity, 26% desulfurization and 27% reduction in the asphaltene content of the upgraded product in comparison to the control reaction using inert sand. The iron nanocatalysts were characterized by SEM, XPS, EDAX, and Mössbauer spectroscopy before and after the upgrading reactions. The results indicated the presence of hematite (Fe2O3 as the predominant iron phase. The data showed that the catalysts were deactivating by particle sintering (~20% increase in particle size and also by carbon deposition. Probable mechanisms of reactions are proposed.

  13. Cross-linking of lens crystallin proteins induced by tryptophan metabolites and metal ions

    DEFF Research Database (Denmark)

    Tweeddale, Helen J; Hawkins, Clare Louise; Janmie, Joane F

    2016-01-01

    Long-wavelength solar UV radiation is implicated in photodamage to the human eye. The human lens contains multiple tryptophan-derived compounds that have significant absorbance bands in the UVA region (λ 315-400 nm) that act as efficient physical filters for these wavelengths. The concentrations...

  14. Quasi-three level Nd:YLF fundamental and Raman laser operating under 872-nm and 880-nm direct diode pumping

    Science.gov (United States)

    Wetter, Niklaus U.; Bereczki, Allan; Paes, João. Pedro Fonseca

    2018-02-01

    Nd:YLiF4 is the gain material of choice whenever outstanding beam quality or a birefringent gain material is necessary such as in certain applications for terahertz radiation or dual-frequency mode-locking. However, for high power CW applications the material is hampered by a low thermal fracture threshold. This problem can be mitigated by special 2D pump set-ups or by keeping the quantum defect to a minimum. Direct pumping into the upper laser level of Nd:YLiF4 is usually performed at 880 nm. For quasi-three level laser emission at 908 nm, direct pumping at this wavelength provides a high quantum defect of 0.97, which allows for very high CW pump powers. Although the direct pumping transition to the upper laser state at 872 nm has a slightly smaller quantum defect of 0.96, its pump absorption cross section along the c-axis is 50% higher than at 880 nm, leading to a higher absorption efficiency. In this work we explore, for the first time to our knowledge, 908 nm lasing under 872 nm diode pumping and compare the results with 880 nm pumping for quasicw and cw operation. By inserting a KGW crystal in the cavity, Raman lines at 990 nm and 972 nm were obtained for the first time from a directly pumped 908 nm Nd:YLF fundamental laser for both quasi-cw and cw conditions.

  15. First studies of 500-nm Cherenkov radiation from 255-MeV electrons in a diamond crystal

    Energy Technology Data Exchange (ETDEWEB)

    Takabayashi, Y., E-mail: takabayashi@saga-ls.jp [SAGA Light Source, 8-7 Yayoigaoka, Tosu, Saga 841-0005 (Japan); Fiks, E.I. [National Research Tomsk Polytechnic University, 634050 Tomsk (Russian Federation); Pivovarov, Yu.L. [National Research Tomsk Polytechnic University, 634050 Tomsk (Russian Federation); National Research Tomsk State University, 634050 Tomsk (Russian Federation)

    2015-06-12

    The first experiment on Cherenkov light from 255-MeV electrons passing through a 50-μm-thick diamond crystal in a special geometry allowing extraction of 500-nm Cherenkov light at a right angle with respect to the electron beam direction has been performed at the injector linac of SAGA Light Source accelerator facility. The dependence of 500-nm Cherenkov light intensity (separated by a band-pass filter) on the crystal rotation angle was measured by a CCD detector. The experimentally obtained rocking curve with an intense maximum is theoretically explained as the projector effect of Cherenkov light deflected by the exit surface of the crystal. The width of the rocking curve is explained by the convolution of the standard Tamm–Frank angular distribution of Cherenkov radiation with chromatic aberration, the multiple scattering of electrons in a crystal, and initial electron beam angular divergence. In addition, it is found that the Cherenkov light intensity did not change under the (220) planar channeling condition, which is consistent with a recent theory. - Highlights: • Cherenkov light from 255-MeV electrons in a diamond crystal has been investigated. • The Cherenkov light from channeled electrons has been observed for the first time. • The experimental results are in good agreement with theory.

  16. Ferric ion mediated photochemical decomposition of perfluorooctanoic acid (PFOA) by 254 nm UV light

    International Nuclear Information System (INIS)

    Wang Yuan; Zhang Pengyi; Pan Gang; Chen Hao

    2008-01-01

    The great enhancement of ferric ion on the photochemical decomposition of environmentally persistent perfluorooctanoic acid (PFOA) under 254 nm UV light was reported. In the presence of 10 μM ferric ion, 47.3% of initial PFOA (48 μM) was decomposed and the defluorination ratio reached 15.4% within 4 h reaction time. While the degradation and defluorination ratio greatly increased to 80.2% and 47.8%, respectively, when ferric ion concentration increased to 80 μM, and the corresponding half-life was shortened to 103 min. Though the decomposition rate was significantly lowered under nitrogen atmosphere, PFOA was efficiently decomposed too. Other metal ions like Cu 2+ and Zn 2+ also slightly improved the photochemical decomposition of PFOA under irradiation of 254 nm UV light. Besides fluoride ion, other intermediates during PFOA decomposition including formic acid and five shorter-chain perfluorinated carboxylic acids (PFCAs) with C7, C6, C5, C4 and C3, respectively, were identified and quantified by IC or LC/MS. The mixture of PFOA and ferric ion had strong absorption around 280 nm. It is proposed that PFOA coordinates with ferric ion to form a complex, and its excitation by 254 nm UV light leads to the decomposition of PFOA in a stepwise way

  17. Mutagenic interactions between near-ultraviolet (365 nm) radiation and alkylating agents in Escherichia coli

    International Nuclear Information System (INIS)

    Moraes, E.C. de; Tyrell, R.M.

    1981-01-01

    The mutagenic interaction between near-ultrviolet (365 nm) radiation and the alkylting agents ehtyl methanesulponate (EMS) and methyl methanesulphonate (MMS) was studied in a repair-component and an excision-deficient stram of Escherichia coli. Near-UV raditation modified the metabolic response of of exposure to these chemicals and either reduced or increased their mutagenic efficiency. Based on these results, an experimental model was formulated to explain the mutagenic interactions that occur between near-UV and various agents that induce prototrophic reverants cia error-prone repair of DNA. According to this model, low doses of near-UV provoke conditions for mutation frequency decline (MFI) and lead to a mutagenic antagonism. With increasing near-Uv doses, damage to constitutive error-free repairs system increases, favouring the error-prone system and inhibiting the MFD. Under these conditions there will be a progressive decrease in antagonism until at high doses an enhancement of mutation frequency (positive interaction) will occur. (orig.)

  18. 48 CFR 315.605 - Content of unsolicited proposals.

    Science.gov (United States)

    2010-10-01

    ... CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Unsolicited Proposals 315.605 Content of... prepared under Government supervision; (b) The methods and approaches stated in the proposal were developed... Title (This certification shall be signed by a responsible management official of the proposing...

  19. 24 CFR 888.315 - Restrictions on retroactive payments.

    Science.gov (United States)

    2010-04-01

    ... PROGRAM, SECTION 202 SUPPORTIVE HOUSING FOR THE ELDERLY PROGRAM AND SECTION 811 SUPPORTIVE HOUSING FOR PERSONS WITH DISABILITIES PROGRAM) SECTION 8 HOUSING ASSISTANCE PAYMENTS PROGRAM-FAIR MARKET RENTS AND... Elderly or Handicapped, and Special Allocations Projects § 888.315 Restrictions on retroactive payments...

  20. A garlic extract protects from ultraviolet B (280-320 nm) radiation-induced suppression of contact hypersensitivity

    International Nuclear Information System (INIS)

    Reeve, V.E.; Bosnic, M.; Rozinova, E.; Boehm-Wilcox, C.

    1993-01-01

    Lyophilized aged garlic extract has been incorporated at concentrations of 0.1%, 1% and 4% by weight into semi purified powdered diets and fed to hairless mice. Under moderate UVB exposure conditions resulting in 58% suppression of the systemic contact hypersensitivity response in control-fed mice, a dose-responsive protection was observed in the garlic-fed mice; contact hypersensitivity in the UVB-exposed mice fed 4% garlic extract was suppressed by only 19%. If the UVB exposure was replaced by topical application of one of a series of lotions containing increasing concentrations of cis-urocanic acid, a dose-responsive suppression of contact hypersensitivity was demonstrated in control-fed mice (urocanic acid at 25, 50, 100 and 200 micrograms per mouse resulting in 22-46% suppression). Mice fed a diet containing 1% aged garlic extract were partially protected from cis-urocanic acid-induced suppression of contact hypersensitivity, with greater protection from the lower concentrations of urocanic acid. Mice fed a diet containing 4% aged garlic extract were protected from all concentrations of urocanic acid. The results indicate that aged garlic extract contains ingredient(s) that protect from UVB-induced suppression of contact hypersensitivity and suggest that the mechanism of protection is by antagonism of the cis-urocanic acid mediation of this form of immunosuppression

  1. 31 CFR 315.64 - Payment, reinvestment, or exchange-voluntary guardian of an incapacitated person.

    Science.gov (United States)

    2010-07-01

    ...-voluntary guardian of an incapacitated person. 315.64 Section 315.64 Money and Finance: Treasury Regulations... exchange—voluntary guardian of an incapacitated person. (a) Payment of bonds. When an adult owner of bonds... an application for recognition as voluntary guardian for the purpose of redeeming the owner's bonds...

  2. Lanthanum (III) regulates the nitrogen assimilation in soybean seedlings under ultraviolet-B radiation.

    Science.gov (United States)

    Huang, Guangrong; Wang, Lihong; Zhou, Qing

    2013-01-01

    Ultraviolet-B (UV-B, 280-320 nm) radiation has seriously affected the growth of plants. Finding the technology/method to alleviate the damage of UV-B radiation has become a frontal topic in the field of environmental science. The pretreatment with rare earth elements (REEs) is an effective method, but the regulation mechanism of REEs is unknown. Here, the regulation effects of lanthanum (La(III)) on nitrogen assimilation in soybean seedlings (Glycine max L.) under ultraviolet-B radiation were investigated to elucidate the regulation mechanism of REEs on plants under UV-B radiation. UV-B radiation led to the inhibition in the activities of the key enzymes (nitrate reductase, glutamine synthetase, glutamate synthase) in the nitrogen assimilation, the decrease in the contents of nitrate and soluble proteins, as well as the increase in the content of amino acid in soybean seedlings. The change degree of UV-B radiation at the high level (0.45 W m(-2)) was higher than that of UV-B radiation at the low level (0.15 W m(-2)). The pretreatment with 20 mg L(-1) La(III) could alleviate the effects of UV-B radiation on the activities of nitrate reductase, glutamine synthetase, glutamate synthase, and glutamate dehydrogenase, promoting amino acid conversion and protein synthesis in soybean seedlings. The regulation effect of La(III) under UV-B radiation at the low level was better than that of UV-B radiation at the high level. The results indicated that the pretreatment with 20 mg L(-1) La(III) could alleviate the inhibition of UV-B radiation on nitrogen assimilation in soybean seedlings.

  3. UVR-induced photoinhibition of summer marine phytoplankton communities from Patagonia

    NARCIS (Netherlands)

    Villafane, Virginia E.; Janknegt, Paul J.; de Graaff, Marco; Visser, Ronald J. W.; de Poll, Willem H. van; Buma, Anita G. J.; Helbling, E. Walter

    During austral summer 2006, experiments were carried out to evaluate the effects of ultraviolet radiation (UVR, 280-400 nm) on carbon fixation of natural phytoplankton assemblages from Patagonia (Argentina). Surface water samples were collected (ca. 100 m offshore) at mid morning using an

  4. 29 CFR 778.315 - Payment for all hours worked in overtime workweek is required.

    Science.gov (United States)

    2010-07-01

    ... OVERTIME COMPENSATION Special Problems Effect of Failure to Count Or Pay for Certain Working Hours § 778... 29 Labor 3 2010-07-01 2010-07-01 false Payment for all hours worked in overtime workweek is required. 778.315 Section 778.315 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION...

  5. Role of cadmium and ultraviolet-B radiation in plants. Influence on photosynthesis and element content in two species of Brassicaceae

    Energy Technology Data Exchange (ETDEWEB)

    Larsson Joensson, Helene

    2001-02-01

    Plants are exposed to many different stress factors during their lifetime. often more than one factor at a time. which highlights the importance of research regarding interaction among stress factors. Cadmium and ultraviolet-B radiation (MB, 280-315 mm) are two potential stress factors in the environment, which have gained increased interest due to atmospheric pollution. In this work the interaction between Cd and UV-B radiation was investigated in two species of Brassicaceae; Brassica napus and Arabidopsis thaliana, the latter including the wild type and phytochelatin-deficient cad1-3. In both species photosynthetic parameters and element content were studied after the plants were exposed to Cd and supplemental UV-B radiation for 14 days. A separate Cd uptake study was carried out on Arabidopsis thaliana to investigate the effect of different Cd pretreatments on Cd uptake. The experiments showed that Cd was the dominant factor, but in Brassica napus, Cd+UV-B showed some interaction effects on energy dissipation and chlorophyll ratios. Generally, Cd decreased the chlorophyll content and influenced photosynthesis by altering oxygen evolution, non-photochemical quenching and the quantum yield. Cadmium had large effects on the content of essential elements, particularly in roots, that may be due to competition during uptake. The Cd uptake study showed that the wild type contained much higher amounts of Cd than the phytochelatin-deficient cad1-3, although Cd uptake is expected to be independent of phytochelatin content. Phytochelatins chelate and transport Cd to the vacuole, thus removing Cd from the cytosol. This compartmentation may disrupt a possible feedback mechanism in the cytosol.

  6. Schoolyard Shade and Sun Exposure: Assessment of Personal Monitoring During Children's Physical Activity.

    Science.gov (United States)

    Vanos, Jennifer K; McKercher, Grant R; Naughton, Kylie; Lochbaum, Marc

    2017-07-01

    Childhood exposure to ultraviolet radiation (UVR) is a major risk factor for the development of melanoma later in life. However, it is challenging to accurately determine personal outdoor exposure to UVR, specifically erythemally weighted UVR (UV E ry ), due to technological constraints, variable time-activity patterns, and the influence of outdoor environmental design. To address this challenge, this study utilized mobile and stationary techniques to examine the UV E ry exposures of 14 children in a schoolyard in Lubbock, TX, in spring 2016. The aims of the study were to examine the influence of artificial shade on personal UV E ry exposures and to assess full sun exposure ratios (ERs) within the same playground microenvironment. On average, personal wrist dosimeters worn during play in the sun measured 18% of the total onsite UV E ry measured by a stationary UV pyranometer. Shade was found to significantly reduce the personal UV E ry exposures by 55%, UVB 280-315 nm exposures by 91%, and the overall solar radiation by 84%. Substantial benefits can be garnered through focused design of children's recreational space to utilize shade-both natural and artificial-to reduce UVR exposures during play, and to extend safe outdoor stays. Finally, although the wrist is a practical location for a dosimeter, it often underestimates full exposures, particularly during physical activity. © 2017 The American Society of Photobiology.

  7. The oncolytic peptide LTX-315 induces cell death and DAMP release by mitochondria distortion in human melanoma cells

    Science.gov (United States)

    Eike, Liv-Marie; Yang, Nannan; Rekdal, Øystein; Sveinbjørnsson, Baldur

    2015-01-01

    Host defense peptides (HDPs) are naturally occurring molecules found in most species, in which they play a significant role in the first line defense against intruding pathogens, and several HDPs have been shown to possess anticancer activity. Structure-activity relationship studies on the HDP bovine lactoferricin revealed a de novo design of a nonamer peptide LTX-315, with oncolytic properties. In the present study, we investigated the oncolytic activity of LTX-315 in human melanoma cells (A375). LTX-315 induced a rapid plasma membrane disruption and cell death within 2 hours. At a low concentration, fluorescence-labeled LTX-315 was internalized and accumulated in cytoplasmic vacuoles in close proximity to the mitochondria. The mitochondrial membrane potential was shown to depolarize as a consequence of LTX-315 treatment and at ultrastructural level, the mitochondria morphology was significantly altered. Release of danger signals (DAMPs) such as ATP, Cytochrome C and HMGB1 into the cell supernatant of cultured cells was evident minutes after peptide treatment. The oncolytic effect of LTX-315 involving perturbation of both the cell membrane and the mitochondria with subsequent release of DAMPs may highlight the ability of LTX-315 to induce complete regression and long-term protective immune responses as previously reported in experimental animal models. PMID:26472184

  8. Assessment of impact noise at 31.5Hz

    NARCIS (Netherlands)

    Lentzen, S.S.K.; Koopman, A.; Salomons, E.M.

    2011-01-01

    Due to the increasing popularity of lightweight building methods, vibrations and low frequency noise have become a greater challenge. This work deals with the assessment of impact noise at the 31.5 Hz octave band. Three possible impact sound sources to determine the sound insulation have been tested

  9. 38 CFR 41.315 - Audit findings follow-up.

    Science.gov (United States)

    2010-07-01

    ... include audit findings from multiple years, it shall include the fiscal year in which the finding... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Audit findings follow-up... (CONTINUED) AUDITS OF STATES, LOCAL GOVERNMENTS, AND NON-PROFIT ORGANIZATIONS Auditees § 41.315 Audit...

  10. An investigation into the inhibitory effect of ultraviolet radiation on Trichophyton rubrum.

    Science.gov (United States)

    Cronin, Leah J; Mildren, Richard P; Moffitt, Michelle; Lauto, Antonio; Morton, C Oliver; Stack, Colin M

    2014-01-01

    Fungal infection of nails, onychomycosis, is predominantly caused by Trichophyton rubrum. This infection is an important public health concern due to its persistent nature and high recurrence rates. Alternative treatments are urgently required. One such alternative is phototherapy involving the action of photothermal or photochemical processes. The aim of this novel study was to assess which wavelengths within the ultraviolet (UV) spectrum were inhibitory and equally important nail transmissible. Initial irradiations of T. rubrum spore suspensions were carried out using a tunable wavelength lamp system (fluence ≤3.1 J/cm(2)) at wavelengths between 280 and 400 nm (UVC to UVA) to evaluate which wavelengths prevented fungal growth. Light-emitting diodes (LEDs) of defined wavelengths were subsequently chosen with a view to evaluate and potentially implement this technology as a low-cost "in-home" treatment. Our experiments demonstrated that exposure at 280 nm using an LED with a fluence as low as 0.5 J/cm(2) was inhibitory, i.e., no growth following a 2-week incubation (p < 0.05; one-way ANOVA), while exposure to longer wavelengths was not. A key requirement for the use of phototherapy in the treatment of onychomycosis is that it must be nail transmissible. Our results indicate that the treatment with UVC is not feasible given that there is no overlap between the antifungal activity observed at 280 nm and transmission through the nail plate. However, a potential indirect application of this technology could be the decontamination of reservoirs of infection such as the shoes of infected individuals, thus preventing reinfection.

  11. First Results from Contamination Monitoring with the WFC3 UVIS G280 Grism

    Science.gov (United States)

    Rothberg, B.; Pirzkal, N.; Baggett, S.

    2011-11-01

    The presence of contaminants within the optical light path of the instrument or telescope can alter photometric zeropoints and the observed flux levels of imaging and spectra, particularly at UV wavelengths. Regular monitoring of a spectro-photometric standard star using photometric filters has been used in the past to monitor the presence of contaminants and (when necessary) re-calibrate zeropoints. However, the use of the WFC3 UVIS Grism mode (G280 filter) may provide a more robust early alert detection system for the presence of contaminants, in particular, those that are photo-polymerized from the bright Earth. These contaminants may collect on surfaces in the optical light path of the telescope. The G280 grism is sensitive to light at wavelengths below the cutoff of the bluest UV filter (F218W). In this ISR, we present: 1) the first results from G280 monitoring for the period of 2010-November through 2011-August; 2) the discovery of an anomaly in the WCS header information of sub-array exposures; and 3) an outline for reducing standard G280 grism observations and the specialized case of observations obtained in sub-array mode.

  12. A novel mouse model for multiple myeloma (MOPC315.BM that allows noninvasive spatiotemporal detection of osteolytic disease.

    Directory of Open Access Journals (Sweden)

    Peter O Hofgaard

    Full Text Available Multiple myeloma (MM is a lethal human cancer characterized by a clonal expansion of malignant plasma cells in bone marrow. Mouse models of human MM are technically challenging and do not always recapitulate human disease. Therefore, new mouse models for MM are needed. Mineral-oil induced plasmacytomas (MOPC develop in the peritoneal cavity of oil-injected BALB/c mice. However, MOPC typically grow extramedullary and are considered poor models of human MM. Here we describe an in vivo-selected MOPC315 variant, called MOPC315.BM, which can be maintained in vitro. When injected i.v. into BALB/c mice, MOPC315.BM cells exhibit tropism for bone marrow. As few as 10(4 MOPC315.BM cells injected i.v. induced paraplegia, a sign of spinal cord compression, in all mice within 3-4 weeks. MOPC315.BM cells were stably transfected with either firefly luciferase (MOPC315.BM.Luc or DsRed (MOPC315.BM.DsRed for studies using noninvasive imaging. MOPC315.BM.Luc cells were detected in the tibiofemoral region already 1 hour after i.v. injection. Bone foci developed progressively, and as of day 5, MM cells were detected in multiple sites in the axial skeleton. Additionally, the spleen (a hematopoietic organ in the mouse was invariably affected. Luminescent signals correlated with serum myeloma protein concentration, allowing for easy tracking of tumor load with noninvasive imaging. Affected mice developed osteolytic lesions. The MOPC315.BM model employs a common strain of immunocompetent mice (BALB/c and replicates many characteristics of human MM. The model should be suitable for studies of bone marrow tropism, development of osteolytic lesions, drug testing, and immunotherapy in MM.

  13. The cause of spatial structure in solar He I 1083 nm multiplet images

    Science.gov (United States)

    Leenaarts, Jorrit; Golding, Thomas; Carlsson, Mats; Libbrecht, Tine; Joshi, Jayant

    2016-10-01

    Context. The He I 1083 nm is a powerful diagnostic for inferring properties of the upper solar chromosphere, in particular for the magnetic field. The basic formation of the line in one-dimensional models is well understood, but the influence of the complex three-dimensional structure of the chromosphere and corona has however never been investigated. This structure must play an essential role because images taken in He I 1083 nm show structures with widths down to 100 km. Aims: We aim to understand the effect of the three-dimensional temperature and density structure in the solar atmosphere on the formation of the He I 1083 nm line. Methods: We solved the non-LTE radiative transfer problem assuming statistical equilibrium for a simple nine-level helium atom that nevertheless captures all essential physics. As a model atmosphere we used a snapshot from a 3D radiation-MHD simulation computed with the Bifrost code. Ionising radiation from the corona was self-consistently taken into account. Results: The emergent intensity in the He I 1083 nm is set by the source function and the opacity in the upper chromosphere. The former is dominated by scattering of photospheric radiation and does not vary much with spatial location. The latter is determined by the photonionisation rate in the He I ground state continuum, as well as the electron density in the chromosphere. The spatial variation of the flux of ionising radiation is caused by the spatially-structured emissivity of the ionising photons from material at T ≈ 100 kK in the transition region. The hotter coronal material produces more ionising photons, but the resulting radiation field is smooth and does not lead to small-scale variation of the UV flux. The corrugation of the transition region further increases the spatial variation of the amount of UV radiation in the chromosphere. Finally we find that variations in the chromospheric electron density also cause strong variation in He I 1083 nm opacity. We compare our

  14. 20 CFR 405.315 - Time and place for a hearing before an administrative law judge.

    Science.gov (United States)

    2010-04-01

    ... administrative law judge will decide whether to have that person appear in person or by video teleconference... administrative law judge. 405.315 Section 405.315 Employees' Benefits SOCIAL SECURITY ADMINISTRATION ADMINISTRATIVE REVIEW PROCESS FOR ADJUDICATING INITIAL DISABILITY CLAIMS Administrative Law Judge Hearing § 405...

  15. 40 CFR 265.315 - Special requirements for containers.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Special requirements for containers..., STORAGE, AND DISPOSAL FACILITIES Landfills § 265.315 Special requirements for containers. Unless they are very small, such as an ampule, containers must be either: (a) At least 90 percent full when placed in...

  16. 40 CFR 264.315 - Special requirements for containers.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Special requirements for containers... FACILITIES Landfills § 264.315 Special requirements for containers. Unless they are very small, such as an ampule, containers must be either: (a) At least 90 percent full when placed in the landfill; or (b...

  17. The effect of the operation modes of a gas discharge low-pressure amalgam lamp on the intensity of generation of 185 nm UV vacuum radiation

    Energy Technology Data Exchange (ETDEWEB)

    Vasilyak, L. M., E-mail: vasilyak@ihed.ras.ru [Russian Academy of Sciences, Joint Institute of High Temperatures (Russian Federation); Drozdov, L. A., E-mail: lit@npo.lit.ru; Kostyuchenko, S. V.; Sokolov, D. V. [ZAO LIT (Russian Federation); Kudryavtsev, N. N.; Sobur, D. A., E-mail: soburda@gmail.com [Moscow Institute for Physics and Technology (Russian Federation)

    2011-12-15

    The effect of the discharge current, mercury vapor pressure, and the inert gas pressure on the intensity and efficiency of the 185 nm line generation are considered. The spectra of the UV radiation (vacuum ultraviolet) transmission by protective coatings from the oxides of rare earth metals and aluminum are investigated.

  18. Ultraviolet-B (280-320 nm) absorbing pigments in the leaves of Silene vulgaris: their role in UV-B tolerance

    Energy Technology Data Exchange (ETDEWEB)

    Staaij, J.W.M. van de; Ernst, W. H.O.; Hakvoort, H. W.J.; Rozema, J. [Vrije Univ., Amsterdam (Netherlands)

    1995-07-01

    The UV-B radiation tolerant perennial herb Silene vulgaris was tested on the influence of incident UV-B fluxes during growth on the synthesis of UV-B absorbing pigments in the leaves. Analysis of methanolic leaf extracts showed a stimulating effect of UV-B on the absorbing ability of leaf extracts. HPLC analysis made clear that UV-B radiation stimulated extractable flavonoid concentrations in leaves, but that UV-B absorption could only be partly attributed to these flavonoids. The contribution of flavonoids to UV-B absorption diminishes if plants mature. Other possible functions of flavonoids in plants growing under elevated UV-B conditions are discussed. (author)

  19. Ultraviolet-B (280-320 nm) absorbing pigments in the leaves of Silene vulgaris: their role in UV-B tolerance

    International Nuclear Information System (INIS)

    Staaij, J.W.M. van de; Ernst, W.H.O.; Hakvoort, H.W.J.; Rozema, J.

    1995-01-01

    The UV-B radiation tolerant perennial herb Silene vulgaris was tested on the influence of incident UV-B fluxes during growth on the synthesis of UV-B absorbing pigments in the leaves. Analysis of methanolic leaf extracts showed a stimulating effect of UV-B on the absorbing ability of leaf extracts. HPLC analysis made clear that UV-B radiation stimulated extractable flavonoid concentrations in leaves, but that UV-B absorption could only be partly attributed to these flavonoids. The contribution of flavonoids to UV-B absorption diminishes if plants mature. Other possible functions of flavonoids in plants growing under elevated UV-B conditions are discussed. (author)

  20. Effect of ultraviolet radiation, smoking and nutrition on hair.

    Science.gov (United States)

    Trüeb, Ralph M

    2015-01-01

    Similar to the rest of the skin, the hair is exposed to noxious environmental factors. While ultraviolet radiation (UVR) and smoking are well appreciated as major factors contributing to the extrinsic aging of the skin, their effects on the condition of hair have only lately attracted the attention of the medical community. Terrestrial solar UVR ranges from approximately 290 to 400 nm; UV-B (290-315 nm) reaches only the upper dermis, while the penetration of UV-A (315-400 nm) into the dermis increases with wavelength. The two most important chronic effects of UVR on the skin and bald scalp are photocarcinogenesis and solar elastosis; however, the effects of UVR on hair have largely been ignored. As a consequence of increased leisure time and a growing popularity of outdoor activities and holidays in the sun, the awareness of sun protection of the skin has become important and should also apply to the hair. Besides being the single-most preventable cause of significant cardiovascular and pulmonary morbidity and an important cause of death, the association of tobacco smoking with various adverse effects on the skin and hair has also been recognized. Increasing public awareness of the association between smoking and hair loss seems to offer a good opportunity for the prevention or cessation of smoking, since the appearance of hair plays an important role in the overall physical appearance and self-perception of people. Finally, the quantity and quality of hair are closely related to the nutritional state of an individual. Normal supply, uptake, and transport of proteins, calories, trace elements, and vitamins are of fundamental importance in tissues with high biosynthetic activity, such as the hair follicle. In instances of protein and calorie malnutrition as well as essential amino acid, trace element, and vitamin deficiencies, hair growth and pigmentation may be impaired. Ultimately, important commercial interest lies in the question of whether increasing the

  1. Generation of 14  W at 589  nm by frequency doubling of high-power CW linearly polarized Raman fiber laser radiation in MgO:sPPLT crystal.

    Science.gov (United States)

    Surin, A A; Borisenko, T E; Larin, S V

    2016-06-01

    We introduce an efficient, single-mode, linearly polarized continuous wave (CW) Raman fiber laser (RFL), operating at 1178 nm, with 65 W maximum output power and a narrow linewidth of 0.1 nm. Single-pass second-harmonic generation was demonstrated using a 20 mm long MgO-doped stoichiometric periodically polled lithium tantalate (MgO:sPPLT) crystal pumped by RFL radiation. Output power of 14 W at 589 nm with 22% conversion efficiency was achieved. The possibility of further power scaling is considered, as no crystal degradation was observed at these power levels.

  2. Super ACO FEL oscillation at 300 nm

    CERN Document Server

    Nutarelli, D; Renault, E; Nahon, L; Couprie, Marie Emmanuelle

    2000-01-01

    Some recent improvements, involving both the optical cavity mirrors and the positron beam dynamics in the storage ring, have allowed us to achieve a laser oscillation at 300 nm on the Super ACO Storage Ring FEL. The Super ACO storage ring is operated at 800 MeV which is the nominal energy for the usual synchrotron radiation users, and the highest energy for a storage ring FEL. The lasing at 300 nm could be kept during 2 h per injection, with a stored current ranging between 30 and 60 mA. The FEL characteristics are presented here. The longitudinal stability and the FEL optics behaviour are also discussed.

  3. A tunable integrated system to simulate colder stellar radiation

    Science.gov (United States)

    Erculiani, Marco S.; Claudi, Riccardo; Barbisan, Diego; Giro, Enrico; Bonato, Matteo; Cocola, Lorenzo; Farisato, Giancarlo; Meneghini, Metteo; Poletto, Luca; Salasnich, Bernardo; Trivellin, Nicola

    2015-09-01

    In the last years, a lot of extrasolar planets have been discovered in any direction of the Galaxy. More interesting, some of them have been found in the habitable zone of their host stars. A large diversity of spectral type, from early types (A) to colder ones (M), is covered by the planetary system host stars. A lot of efforts are done in order to find habitable planets around M stars and indeed some habitable super earths were found. In this framework, "Atmosphere in a Test Tube", a project started at Astronomical observatory of Padua, simulates planetary environmental condition in order to understand how and how much the behavior of photosynthetic bacteria in different planetary/star scenarios can modify the planet atmosphere. The particular case of an habitable planet orbiting a M dwarf star is under study for the time being. The irradiation of an M star, due to its lower surface temperature is very different in quality and quantity by the irradiation of a star like our Sun. We would like to describe the study of feasibility of a new kind of tunable led stellarlight simulator capable to recreate the radiation spectrum of M type stars (but with the potential to be expanded even to F, G, K star spectra types) incident on the planet. The radiation source is a multiple LED matrix cooled by means of air fan technology. In order to endow it with modularity this device will be composed by a mosaic of circuit boards arranged in a pie-chart shape, on the surface of which will be welded the LEDs. This concept is a smart way in order to replace blown out pieces instead of changing the entire platform as well as implement the device with new modules suitable to reproduce other type of stars. The device can be driven by a PC to raise or lower the intensity of both each LED and the lamp, in order to simulate as close as possible a portion of the star spectrum. The wavelength intervals overlap the limits of photosynthetic pigment absorption range (280-850 nm), while the

  4. The response of bean plants to UV-B radiation under different irradiances of background visible light

    International Nuclear Information System (INIS)

    Cen, Y.P.; Bornman, J.F.

    1990-01-01

    Plants of Phaseolus vulgaris L. (cv. Stella) were grown in controlled conditions under three different irradiances of visible light with or without UV-B (280–320nm) radiation. The biologically effective UV-B radiation (UV-BBE) was 6.17 kJ m −2 d −1 , and simulated a c. 5% decrease in stratospheric ozone at 55.7°N, 13.4°E. The photon flux densities of the photosynthetically active radiation (PAR, 400–700 nm) were either 700 μmol m −2−1 (HL), 500, μmol m −2 s −1 (ML) or 230 μmol m −2 s −1 PAR (LL). Under high light (HL) conditions plus UV-B radiation, bean plants appeared most resistant to the enhanced levels of UV-B radiation, and responded only by increasing leaf thickness by c. 18%. A small increase in UV screening pigments was also observed. Both the lower irradiances (ML and LL) increased the sensitivity of the plants to UV-B radiation. Changes in leaf structure were also observed. Photosystem II was inhibited under ML and LL together with UV-B radiation, as determined by Chi fluorescence induction and calculation of the fluorescence half-rise times. Leaf reflectivity measurements showed that the amount of PAR able to penetrate leaves of UV-B treated plants was reduced, and that a possible correlation may exist between the reduced PAR levels, loss of Chi and lowered photosynthetic activity, especially for LL +UV-B grown plants, where surface reflection from leaves was highest. Changes in leaf chlorophyll content were mostly confined to plants grown under LL + UV-B, where a decrease of c. 20% was found. With regard to protective pigments (the carotenoids and UV screening pigments) plants subjected to different visible light conditions responded differently. Among the growth parameters measured, there was a substantial decrease in leaf area, particularly under LL + UV-B (c. 47% relative to controls), where leaf dry weight was also reduced by c. 25%. (author)

  5. The in vitro photolysis of whole rat lenses using focused 290nm laser radiation

    International Nuclear Information System (INIS)

    Hibbard, L.B.; Kirk, N.J.; Borkman, R.F.

    1985-01-01

    Whole rat lenses have been irradiated with a UV laser at 290 or 298 nm focused to a 0.08 mm diameter spot. The irradiated spot was analyzed using fluorescence spectroscopy and it was observed that the intensity of fluorescence fell as the irradiation proceeded. These observations were interpreted in terms of a model which postulates photolysis of tryptophan, primarily present as residues in lens proteins, and formation of photoproducts which absorb the UV laser radiation to an ever-increasing extent as the irradiation proceeds. Evidence is also presented which indicates that an observed fast component of the tryptophan fluorescence decay results from local heating of the lens tissues due to energy dissipation by the laser. Tryptophan residues can be photolyzed by UV light in the whole lens, in vitro, in a fashion entirely analogous to that reported previously only for lens protein solutions. The photochemical behavior of lens protein solutions is relevant to whole lens photolysis and no special protective mechanism appears to be operative in the intact organ. (author)

  6. Effects of ultraviolet-B radiation on plants during mild water stress, 4: The insensitivity of soybean internal water relations to ultraviolet-B radiation

    International Nuclear Information System (INIS)

    Teramura, A.H.; Forseth, I.N.; Lydon, J.

    1984-01-01

    The combined effects of ultraviolet-B (UV-B, 280–320 nm) radiation and water stress were investigated on the water relations of greenhouse grown soybean [Glycine max (L.) Merr. cv. Essex]. On a weighted (Caldwell 1971), total daily dose basis, plants received either 0 or 3 000 effective J m 2 UV-B BE supplied by filtered FS-40 sunlamps. The latter dose simulated the solar UV-B radiation anticipated at College Park, Maryland, U.S.A. (39°N latitude) in the event that the global stratospheric ozone column is reduced by 25%. Plants were either well-watered or preconditioned by drought stress cycles. Diurnal measurements of water potential and stomatal conductance were made on the youngest fully expanded leaf. Various internal water relations parameters were determined for detached leaves. Plants were monitored before, during and after water stress. There were no significant differences in leaf water potential or stomatal conductance between treatments before plants were preconditioned to water stress. However, drought stress resulted in significantly lower midday and afternoon leaf water potentials and lower leaf conductances as compared to well-watered plants. UV-B radiation had no additional effect on leaf water potential; however, UV did result in lower leaf conductances in plants preconditioned to water stress. Turgid weight:dry weight ratio, elastic modulus, bound water and relative water content were unaffected by UV-B radiation. Osmotic potentials at full and zero turgor were significantly lower in the drought stressed treatments as compared to well-watered plants. (author)

  7. 31 CFR 594.315 - United States person; U.S. person.

    Science.gov (United States)

    2010-07-01

    ... (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY GLOBAL TERRORISM SANCTIONS REGULATIONS General Definitions § 594.315 United States person; U.S. person. The term United States person or...

  8. UV-induced cell damage is species-specific among aquatic phagotrophic protists

    NARCIS (Netherlands)

    Sommaruga, R; Buma, AGJ

    2000-01-01

    The sensitivity to ultraviolet radiation (UVR, 280-400 nm) of ten species of freshwater and marine phagotrophic protists was assessed in short-term (4 h) laboratory experiments. Changes in the motility and morphology of the cells, as well as direct quantification of DNA damage, were evaluated. The

  9. Vitamin D production after UVB exposure - a comparison of exposed skin regions.

    Science.gov (United States)

    Osmancevic, Amra; Sandström, Katarina; Gillstedt, Martin; Landin-Wilhelmsen, Kerstin; Larkö, Olle; Wennberg Larkö, Ann-Marie; F Holick, Michael; Krogstad, Anne-Lene

    2015-02-01

    Cholecalciferol is an essential steroid produced in the skin by solar ultraviolet B radiation (UVB 290-315nm). Skin production of cholecalciferol depends on factors affecting UVB flux, age and exposed skin area. Serum cholecalciferol and 25-hydroxyvitamin D3 [25(OH)D3] concentrations were measured after UVB irradiation of 3 different skin areas to compare the skin capacity to produce vitamin D in different anatomic sites in the same individuals. Ten voluntary Caucasians (skin photo type II & III, aged 48±12years (±SD)) were exposed to broadband UVB (280-320nm) between February and April. Hands and face, upper body and whole body were exposed to a suberythemic dose of UVB (median 101mJ/cm(2) (min 66, max 143)) (for 3 subsequent days 24h apart with a wash out period of about 3weeks (median 18days (min 11, max 25)) between the exposures of respective area. Serum concentrations of cholecalciferol and 25(OH)D3, were measured immediately before the first and 24h after the last dose of radiation. There was a significantly higher increase in serum cholecalciferol after UVB exposure of the two larger skin areas compared to face and hands, but no difference in increase was found between upper body and whole body exposures. Exposure of a larger skin area was superior to small areas and gave greater increase in both serum cholecalciferol and serum 25(OH)D3 concentrations. However, exposure of face and hands, i.e. only 5% of the body surface area, was capable of increasing serum concentrations of 25(OH)D3. Copyright © 2015 Elsevier B.V. All rights reserved.

  10. 45 CFR 149.315 - Reimbursement conditioned upon available funds.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Reimbursement conditioned upon available funds... TO HEALTH CARE ACCESS REQUIREMENTS FOR THE EARLY RETIREE REINSURANCE PROGRAM Reimbursement Methods § 149.315 Reimbursement conditioned upon available funds. Notwithstanding a sponsor's compliance with...

  11. 31 CFR 595.315 - United States person; U.S. person.

    Science.gov (United States)

    2010-07-01

    ... (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY TERRORISM SANCTIONS REGULATIONS General Definitions § 595.315 United States person; U.S. person. The term United States person or U.S...

  12. 48 CFR 315.606-1 - Receipt and initial review.

    Science.gov (United States)

    2010-10-01

    ... CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Unsolicited Proposals 315.606-1 Receipt and initial review. (d) OPDIVs shall not refuse consideration of an unsolicited proposal because an organization initially submitted it as a grant application. However, OPDIVs shall not award contracts based on...

  13. The effect of solar ultraviolet radiation (UVR on induction of skin cancers

    Directory of Open Access Journals (Sweden)

    Marta Pacholczyk

    2016-04-01

    Full Text Available Ultraviolet radiation is a physical mutagenic and cancerogenic factor. About 95% of ultraviolet A (UVA (320–400 nm and 5% of UVB (280–320 nm reach the Earth’s surface. Melanin is a natural skin protective factor against UV radiation. Skin cancers associated with long-term exposure to UV radiation are: basal cell carcinoma (BCC, squamous cell carcinoma (SCC and cutaneous malignant melanoma (CMM. The high risk of BCC development is related to acute and repeated exposure to UV causing sunburn. Molecular studies of BBC demonstrated disorders in sonic hedgehog (SHH cell signaling regulation pathway, associated with the suppressor protein patched homolog 1 gene (PTCH1 mutations. The risk of the BCC development is related to the polymorphism of melanokortin-1 receptor gene (MC1R. Tumor P53 gene mutations observed in BCC cells has been classified as secondary genetic changes. In SCC cells UV-induced mutations were mostly related to P53 gene. Increased expression of cyclooxigenase- 2 gene (COX-2 plays a significant role in the development of SCC. Other pathogenetic factors include intensification of the synthesis of pro-inflammatory cytokines (tumor necrosis factor α (TNF-α, interleukin-1 α (IL-1α, IL-1β and IL-6. Currently, the role of UVB has been recognized in the pathogenesis of CMM. In CMM cells the following gene mutations were noted: cyclindependent kinase inhibitor 2A INK4A (p16INK4A, cyclin-dependent kinase 4 (CDK4, Ras, phosphatase and tensin homolog deleted on chromosome 10 (PTEN and proto-oncogene B-Raf (BRAF. The BRAF gene mutations were observed in ~50% of CMM cases. Mutations of P53 gene are not characteristic of CMM cells. Med Pr 2016;67(2:255–266

  14. 1090 nm infrared radiation at close to threshold dose induces cataract with a time delay.

    Science.gov (United States)

    Yu, Zhaohua; Schulmeister, Karl; Talebizadeh, Nooshin; Kronschläger, Martin; Söderberg, Per G

    2015-03-01

    To investigate whether infrared radiation (IRR)-induced cataract is instant or is associated with a time delay between the exposure and the onset of lens light scattering after an exposure to just above threshold dose. Six-weeks-old albino Sprague-Dawley female rats were unilaterally exposed to 197 W/cm2 IRR at 1090 nm within the dilated pupil. In the first experiment, the animals were exposed with four exposure times of 5, 8, 13 and 20 second, respectively. At 24 hr after exposure, the light scattering in both exposed and contralateral not exposed lenses was measured. Based on the first experiment, four postexposure time groups were exposed unilaterally to 1090 nm IRR of 197 W/cm2 for 8 second. At 6, 18, 55 and 168 hr after exposure, the light scattering in both lenses was measured. A 197 W/cm2 IRR-induced light scattering in the lens with exposures of at least 8 second. Further, after exposure to IRR of 197 W/cm2 for 8 second, the light-scattering increase in the lens was delayed approximately 16 hr after the exposure. There is a time delay between the exposure and the onset of cataract after exposure to close to threshold dose implicating that either near IRR cataract is photochemical or there is a time delay in the biological expression of thermally induced damage. © 2014 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

  15. 8 CFR 280.53 - Civil monetary penalties inflation adjustment.

    Science.gov (United States)

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Civil monetary penalties inflation... REGULATIONS IMPOSITION AND COLLECTION OF FINES § 280.53 Civil monetary penalties inflation adjustment. (a) In general. In accordance with the requirements of the Federal Civil Penalties Inflation Adjustment Act of...

  16. 41 CFR 102-75.280 - What information concerning a proposed disposal must a disposal agency provide to the Attorney...

    Science.gov (United States)

    2010-07-01

    ... applicability of antitrust laws? 102-75.280 Section 102-75.280 Public Contracts and Property Management Federal... PROPERTY DISPOSAL Surplus Real Property Disposal Applicability of Antitrust Laws § 102-75.280 What... the applicability of antitrust laws? The disposal agency must promptly provide the Attorney General...

  17. 40 CFR 280.42 - Requirements for hazardous substance UST systems.

    Science.gov (United States)

    2010-07-01

    ... automatic line leak detector in accordance with § 280.44(a). (5) Other methods of release detection may be...-water intrusion with the ability to contain or detect a release of regulated substances; and (iii...

  18. 31 CFR 315.36 - Payment during life of sole owner.

    Science.gov (United States)

    2010-07-01

    ...) FISCAL SERVICE, DEPARTMENT OF THE TREASURY BUREAU OF THE PUBLIC DEBT REGULATIONS GOVERNING U.S. SAVINGS... § 315.36 Payment during life of sole owner. A savings bond registered in single ownership form (i.e...

  19. Solar UVR-induced DNA damage and inhibition of photosynthesis in phytoplankton from Andean lakes of Argentina

    NARCIS (Netherlands)

    Villafane, VE; Buma, AGJ; Boelen, P; Helbling, EW

    2004-01-01

    During January 1999, studies were carried out in temperate lakes of the Andean region of Argentina (41degreesS, 71degreesW) to determine the short-term effects of solar ultraviolet radiation (UVR, 280-400 nm) upon natural phytoplankton assemblages. Organisms from one 'clear' (Lake Moreno) and two

  20. Impact of UV Radiation on Genome Stability and Human Health.

    Science.gov (United States)

    Roy, Sujit

    2017-01-01

    Gradual depletion of the atmospheric ozone layer during the past few years has increased the incidence of solar UV radiation specifically the UV-C on earth's surface is one of the major environmental concerns because of the harmful effects of this radiation in all forms of life. The solar UV radiation including the harmful wavelength range of UV-B (280-320 nm) represents a significant climatic stress for both animals and plants, causing damage to the fundamental biomolecules such as DNA, proteins and lipids, thus activating genotoxic stress and induces genome instability. When DNA absorbs UV-B light, energy from the photon causes covalent linkages to form between adjacent pyrimidine bases, creating photoproducts, primarily cyclobutane pyrimidine dimers (CPDs) and pyrimidine-6,4-pyrimidinone photoproduct (6,4PPs). Pyrimidine dimers create distortions in the DNA strands and therefore can inhibit DNA replication as well transcription. Lack of efficient repair of UV-induced DNA damage may induce the formation of DNA double stand breaks (DSBs), one of the serious forms of damage in DNA double helix, as well as oxidative damage. Unrepaired DSBs in the actively dividing somatic cells severely affect cell growth and development, finally results in loss of cell viability and development of various diseases, such as cancer in man.This chapter mainly highlights the incidence of solar UV-radiation on earth's surface along with the formation of major types of UV-induced DNA damage and the associated repair mechanisms as well as methods of detecting DNA damage and finally our present understanding on the impact on solar UV radiation on human health.

  1. 41 CFR 102-38.315 - Are we required to use Alternative Disputes Resolution for sales contracts?

    Science.gov (United States)

    2010-07-01

    ... Alternative Disputes Resolution for sales contracts? 102-38.315 Section 102-38.315 Public Contracts and... required to use Alternative Disputes Resolution for sales contracts? No, you are not required to use Alternative Disputes Resolution (ADR) for sales contracts. However, you are encouraged to use ADR procedures...

  2. Increase of the photosensitivity of undoped poly(methylmethacrylate) under UV radiation at 325 nm

    DEFF Research Database (Denmark)

    Sáez-Rodríguez, D.; Nielsen, Kristian; Bang, Ole

    2014-01-01

    in undoped PMMA mPOFs with a hexagonal structure of three rings in the inner cladding. Two sets of FBGs were inscribed at two different resonant wavelengths (827 nm and 1562 nm) at different strains using an UV He-Cd laser at 325 nm focused by a lens and scanned over the fibre. We observed an increase...

  3. 13 CFR 315.6 - Firm eligibility for Adjustment Assistance.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Firm eligibility for Adjustment..., DEPARTMENT OF COMMERCE TRADE ADJUSTMENT ASSISTANCE FOR FIRMS General Provisions § 315.6 Firm eligibility for Adjustment Assistance. (a) Firms participate in the Trade Adjustment Assistance for Firms program in...

  4. Creation and investigation of powerful EUV sources (λ ∼ 13.5 nm)

    International Nuclear Information System (INIS)

    Borisov, V. M.; Borisova, G. N.; Vinokhodov, A. Yu.; Ivanov, A. S.; Kiryukhin, Yu. B.; Mishchenko, V. A.; Prokofiev, A. V.; Khristoforov, O. B.

    2010-01-01

    Results are presented from experimental studies of repetitively pulsed EUV (λ = 13.5 ± 0.135 nm) sources based on a laser-initiated discharge in tin vapor between rotating disk electrodes. Radiative characteristics of two sources with different systems of tin supply onto the electrode surface and different types of power supply have been compared. A number of new effects have been revealed at pulse repetition rates as high as ∼4000 Hz. A mean radiation power of 520 W into the 2π solid angle has been achieved in the spectral band 13.5 ± 0.135 nm at a deposited electrical power of 24 kW.

  5. Creation and investigation of powerful EUV sources (λ ≈ 13.5 nm)

    Science.gov (United States)

    Borisov, V. M.; Borisova, G. N.; Vinokhodov, A. Yu.; Ivanov, A. S.; Kiryukhin, Yu. B.; Mishchenko, V. A.; Prokofiev, A. V.; Khristoforov, O. B.

    2010-03-01

    Results are presented from experimental studies of repetitively pulsed EUV (λ = 13.5 ± 0.135 nm) sources based on a laser-initiated discharge in tin vapor between rotating disk electrodes. Radiative characteristics of two sources with different systems of tin supply onto the electrode surface and different types of power supply have been compared. A number of new effects have been revealed at pulse repetition rates as high as ˜4000 Hz. A mean radiation power of 520 W into the 2π solid angle has been achieved in the spectral band 13.5 ± 0.135 nm at a deposited electrical power of 24 kW.

  6. 40 CFR 280.112 - Drawing on financial assurance mechanisms.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 26 2010-07-01 2010-07-01 false Drawing on financial assurance... OF UNDERGROUND STORAGE TANKS (UST) Financial Responsibility § 280.112 Drawing on financial assurance... agency may draw on a standby trust fund when: (1) The Director makes a final determination that a release...

  7. Effects of lanthanum(III) on nitrogen metabolism of soybean seedlings under elevated UV-B radiation.

    Science.gov (United States)

    Cao, Rui; Huang, Xiao-hua; Zhou, Qing; Cheng, Xiao-ying

    2007-01-01

    The hydroponic culture experiments of soybean bean seedlings were conducted to investigate the effect of lanthanum (La) on nitrogen metabolism under two different levels of elevated UV-B radiation (UV-B, 280-320 nm). The whole process of nitrogen metabolism involves uptake and transport of nitrate, nitrate assimilation, ammonium assimilation, amino acid biosynthesis, and protein synthesis. Compared with the control, UV-B radiation with the intensity of low level 0.15 W/m2 and high level 0.45 W/m2 significantly affected the whole nitrogen metabolism in soybean seedlings (p nitrogen-metabolism-related enzymes, such as: nitrate reductase (NR) to the nitrate reduction, glutamine systhetase (GS) and glutamine synthase (GOGAT) to the ammonia assimilation, while it increased the content of free amino acids and decreased that of soluble protein as well. The damage effect of high level of UV-B radiation on nitrogen metabolism was greater than that of low level. And UV-B radiation promoted the activity of the anti-adversity enzyme glutamate dehydrogenase (GDH), which reduced the toxicity of excess ammonia in plant. After pretreatment with the optimum concentration of La (20 mg/L), La could increase the activity of NR, GS, GOGAT, and GDH, and ammonia assimilation, but decrease nitrate and ammonia accumulation. In conclusion, La could relieve the damage effect of UV-B radiation on plant by regulating nitrogen metabolism process, and its alleviating effect under low level was better than that under the high one.

  8. Modification of genetic effects of gamma radiation by laser radiation

    International Nuclear Information System (INIS)

    Khotyljova, L.V.; Khokhlova, S.A.; Khokhlov, I.V.

    1988-01-01

    Full text: Mutants obtained by means of ionizing radiation and chemical mutagens often show low viability and productivity that makes their use in plant breeding difficult. Methods reducing the destructive mutagen action on important functions of plant organism and increasing quality and practical value of induced mutants would be interesting. We believe that one method for increasing efficiency of experimental mutagenesis in plants is the application of laser radiation as a modificator of genetic effects of ionizing radiation and chemical mutagens. Combined exposure of wheat seedlings to a gamma radiation dose of 2 kR and to laser radiation with the wave length of 632.8 nm (power density - 20 mVt/cm 2 , exposure - 30 min.) resulted in reducing the chromosomal aberration percentage from 30.5% in the gamma version to 16.3% in the combined treatment version. A radiosensibilizing effect was observed at additional exposure of gamma irradiated wheat seeds to laser light with the wave length of 441.6 nm where chromosomal aberration percentage increased from 22% in the gamma-irradiation version to 31% in the combined treatment version. By laser radiation it is also possible to normalize mitotic cell activity suppressed by gamma irradiation. Additional seedling irradiation with the light of helium-neon laser (632.8 nm) resulted in recovery of mitotic cell activity from 21% to 62% and increasing the average content of DNA per nucleus by 10%. The influence of only laser radiation on plant variability was also studied and it was shown that irradiation of wheat seeds and seedlings with pulsed and continuous laser light of visible spectrum resulted in phenotypically altered forms in M 2 . Their frequencies was dependent upon power density, dose and radiation wave length. Number of altered forms increased in going from long-wave to short-wave spectrum region. In comparing efficiency of different laser types of pulsed and continuous exposure (dose - 180 J/cm 2 ) 2% of altered

  9. 26 CFR 1.280C-1 - Disallowance of certain deductions for wage or salary expenses.

    Science.gov (United States)

    2010-04-01

    ... salary expenses. 1.280C-1 Section 1.280C-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE... certain deductions for wage or salary expenses. If an employer elects to claim the targeted jobs credit... deduction for wage or salary expenses paid or incurred in the year the credit is earned by the amount...

  10. Lyman-alpha detector designed for rocket measurements of the direct solar radiation at 121.5 nm

    International Nuclear Information System (INIS)

    Guineva, V.; Tashev, V.; Witt, G.; Gumbel, J.; Khaplanov, M.

    2007-01-01

    Rocket measurements of the direct Lyman-alpha radiation penetrating in the atmosphere were planned during the HotPay I rocket experiment, June 2006, Project ASLAF (Attenuation of the Solar Lyman-Alpha Flux), Andoya Rocket Range (ARR), Norway. The basic goal of ASLAF project was the study of the processes in the summer mesosphere and thermosphere (up to 110 km), at high latitudes using the Lyman-alpha measurements. The resonance transition 2 P- 2 S of the atomic hydrogen (Lyman-alpha emission) is the strongest and most conspicuous feature in the solar EUV spectrum. Due to the favourable circumstance, that the Lyman-alpha wavelength (121.5 nm) coincides with a minimum of the O 2 absorption spectrum, the direct Lyman-alpha radiation penetrates well in the mesosphere. The Lyman-alpha radiation is the basic agent of the NO molecules ionization, thus generating the ionospheric D-layer, and of the water vapour photolysis, being one of the main H 2 O loss processes. The Lyman-alpha radiation transfer depends on the resonance scattering from the hydrogen atoms in the atmosphere and on the O 2 absorption. Since the Lyman-alpha extinction in the atmosphere is a measure for the column density of the oxygen molecules, the atmospheric temperature profile can be calculated thereof. The detector of solar Lyman-alpha radiation was manufactured in the Stara Zagora Department of the Solar-Terrestrial Influences Laboratory (STIL). Its basic part is an ionization chamber, filled in with NO. A 60 V power supply is applied to the chamber. The produced photoelectric current from the sensor is fed to a 2-channels amplifier, providing an analogue signal. The characteristics of the Lyman-alpha detector were studied. It passed successfully all tests and the results showed that the instrument could be used in rocket experiments to measure the Lyman-alpha flux. From the measurements of the detector, the Lyman-alpha vertical profile can be obtained. The forthcoming scientific data analysis will

  11. A morphological and cytological study of Petunia hybrida exposed to UV-B radiation

    International Nuclear Information System (INIS)

    Staxén, I.; Bornmann, J.F.

    1994-01-01

    The aim of this study was to investigate whether the cytoskeleton, and in particular the microtubular system, is affected by enhanced levels of ultraviolet-B (280–320 nm, 9 kJ m −2 day −1 biologically effective UV-B radiation) radiation in epidermal cells of Petunia x hybrida Vilm, isolated from leaves of plants grown under UV-B radiation and visible light. In addition, morphological changes during development were monitored. In a previous study microtubules were depolymerized and delays in the different stages of the cell cycle were found when protoplasts of Petunia were irradiated with UV-B radiation (Staxén et al. 1993. Protoplasma 173: 70–76). Thus it was of interest to ascertain whether the cytoskeleton would be similarly affected in an intact system. Assuming an effect of UV-B radiation on the microtubular system, we wished to determine whether this could be correlated to concomitant changes in leaf morphology. Plants of Petunia hybrida were grown in greenhouse conditions in the presence or absence of UV-B radiation. During the course of the experiment, samples were taken from young, expanding leaves and from older, fully expanded leaves and prepared for localization and analysis of microtubules from the adaxial epidermal cells. Morphology rather than the cytoskeleton was affected by UV radiation, despite the fact that the epidermal cytoskeleton would most likely be affected, since it is located in the cells which form the first intercepting layer for incident radiation. Morphological changes under UV-B radiation, as compared to those under control conditions, were reflected in earlier flowering and an increase in leaf number. Cell division was thus stimulated as was also evidenced from the increased leaf area. Our results indicate that the number of stomata differentiated on a leaf area basis was not altered although the number of stomata per epidermal cell was reduced. (author)

  12. Course for monitored education at distance: 'Introduction to basic aspects of radiation physics in NM'

    International Nuclear Information System (INIS)

    Lopez, Adlin; Palau, Aley; Petrirena, Gregorio; Cardenas, Ana Ivis

    2008-01-01

    Full text: Nuclear Medicine became a multimodality speciality, related with a lot of personnel not specialized in NM techniques: who have not training in radiation aspects. These projects try to evaluate the use of specialized multimedia product for a monitored education at distance of personnel who start to be related with Nuclear Medicine Techniques like nurses, surgeons, rheumatologists, etc. The multimedia product included two items: Introduction to Nuclear Medicine Techniques and Basic aspects of radiation physics. Each item contents an audio-visual conference (Power Point) and a charter (PDF): with theoretic aspects, understand verification questions and self-evaluation activities. The product need only a PC compatible with window 98 (or more advanced version), and 130MBy of memory spaced for archive. In order to verify the effectiveness of the distance course, we tested it in 10 students: 1 nurse, 1 radio-pharmacist, 1 cardiologist, 1 neurologist, 6 technologists. After consult and clarify their doubts, a final test was applied in order to check the knowledge acquired. With 100 point of maximum store and 60 point minimum to pass, the test contented 2 types of questions: true or false choice (with 50 aspects to verify 1.5 point/ correct answer) and many correct choices (5 questions, 5 point/correct answer). The average result was 85.6 points/ students: 6 -Excellent (90-100 points) , 3 -Very good (80-89 points) and 1 -Good (70-79 points). The course was polled about the quality of the material and their comprehension degree, asking the student to make suggestions if were needed. The average evaluation was 94 points (91-95 points). The suggestions made were: increase the number of examples and practical sequences, the understand verification questions and include monitored practical exercise. Conclusion: the product can be useful for a monitored education at distance of personnel who start to be related with Nuclear Medicine Techniques. Recommendation: The

  13. 26 CFR 1.280F-2T - Limitations on recovery deductions and the investment tax credit for certain passenger...

    Science.gov (United States)

    2010-04-01

    ... investment tax credit for certain passenger automobiles (temporary). 1.280F-2T Section 1.280F-2T Internal... TAXES Items Not Deductible § 1.280F-2T Limitations on recovery deductions and the investment tax credit for certain passenger automobiles (temporary). (a) Limitation on amount of investment tax credit—(1...

  14. 30 CFR 280.21 - What must I do in conducting G&G prospecting or scientific research?

    Science.gov (United States)

    2010-07-01

    ... scientific research? 280.21 Section 280.21 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE... prospecting or scientific research? While conducting G&G prospecting or scientific research activities under a... you are prospecting or conducting scientific research activities. (b) Consult and coordinate your G&G...

  15. Effect of solar radiation (UV and visible) at high altitude on CAM-cycling and phenolic compound biosynthesis in Sedum album

    International Nuclear Information System (INIS)

    Bachereau, F.; Marigo, G.; Asta, J.

    1998-01-01

    The field experiment was carried out in order to compare the response of a CAM plant, Sedum album L., to solar radiation at a high altitude (2 100 m) with that at a low altitude location with respect to CAM and phenolic content. Treatment sites included (1) sun-exposed, low altitude, (2) sun-exposed, high altitude with different light treatments, including UV-B and UV-B + A screening, and (3) shade at high altitude. After a 70-day treatment period, CAM-cycling and phenolic compound content were analysed, and high altitude treatments were compared to the low altitude control. The sun-exposed low altitude control was characterized by CAM-cycling and a low phenolic compound content during the experiment. In plants transplanted to the high altitude, only the shaded group maintained a CAM-cycling and a phenolic compound content similar to those of the sun-exposed low altitude control. Samples under UV-B and UV-B + A filters showed similar responses, suggesting the absence of a specific UV-A radiation effect. The screening of UV-B or UV-B + A radiation allowed plants to partially maintain a CAM-cycling and induced a decrease in phenolic compound content. These responses under UV filters were, however, intermediate between those observed in sun-exposed and shaded groups. These results demonstrate a specific effect of radiation from both visible (400–800 nm) and UV-B (280–320 nm) bands on both CAM-cycling and phenolic biosynthesis in S. album L. plants. These light-dependent effects are discussed on a physiological basis and a possible interaction between CAM-cycling and phenolic metabolism is suggested. (author)

  16. Diode-pumped quasi-three-level Nd:GdV O4–Nd:YAG sum-frequency laser at 464 nm

    International Nuclear Information System (INIS)

    Lu, Jie

    2014-01-01

    We report a laser architecture to obtain continuous-wave (cw) blue radiation at 464 nm. A 808 nm diode pumped a Nd:GdV O 4 crystal emitting at 912 nm. A part of the pump power was then absorbed by the Nd:GdV O 4 crystal. The remainder was used to pump a Nd:YAG crystal emitting at 946 nm. Intracavity sum-frequency mixing at 912 and 946 nm was then realized in a LiB 3 O 5 (LBO) crystal to produce blue radiation. We obtained a cw output power of 1.52 W at 464 nm with a pump laser diode emitting 18.4 W at 808 nm. (letter)

  17. 76 FR 81360 - Special Conditions: Gulfstream Aerospace LP (GALP) Model G280 Airplane, Operation Without Normal...

    Science.gov (United States)

    2011-12-28

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 25 [Docket No. FAA-2011-1172: Special Conditions No. 25-453-SC] Special Conditions: Gulfstream Aerospace LP (GALP) Model G280... Aerospace LP (GALP) Model G280 airplane. This airplane will have a novel or unusual design feature...

  18. 40 CFR 280.95 - Financial test of self-insurance.

    Science.gov (United States)

    2010-07-01

    ... least $10 million? ___ 8. Is line 6 at least 10 times line 3? ___ 9. Have financial statements for the.... (f) The Director of the implementing agency may require reports of financial condition at any time... 40 Protection of Environment 26 2010-07-01 2010-07-01 false Financial test of self-insurance. 280...

  19. Photodissociation of acrylonitrile at 193 nm: A photofragment translational spectroscopy study using synchrotron radiation for product photoionization

    International Nuclear Information System (INIS)

    Blank, D.A.; Suits, A.G.; Lee, Y.T.; North, S.W.; Hall, G.E.

    1998-01-01

    We have investigated the photodissociation of acrylonitrile (H 2 CCHCN) at 193 nm using the technique of photofragment translational spectroscopy. The experiments were performed at the Chemical Dynamics Beamline at the Advanced Light Source and used tunable vacuum ultraviolet synchrotron radiation for product photoionization. We have identified four primary dissociation channels including atomic and molecular hydrogen elimination, HCN elimination, and CN elimination. There is significant evidence that all of the dissociation channels occur on the ground electronic surface following internal conversion from the initially optically prepared state. The product translational energy distributions reflect near statistical simple bond rupture for the radical dissociation channels, while substantial recombination barriers mediate the translational energy release for the two molecular elimination channels. Photoionization onsets have provided additional insight into the chemical identities of the products and their internal energy content. copyright 1998 American Institute of Physics

  20. A large area transition radiation detector for the NOMAD experiment

    Science.gov (United States)

    Bassompierre, G.; Bermond, M.; Berthet, M.; Bertozzi, T.; Détraz, C.; Dubois, J.-M.; Dumps, L.; Engster, C.; Fazio, T.; Gaillard, G.; Gaillard, J.-M.; Gouanère, M.; Manola-Poggioli, E.; Mossuz, L.; Mendiburu, J.-P.; Nédélec, P.; Palazzini, E.; Pessard, H.; Petit, P.; Petitpas, P.; Placci, A.; Sillou, D.; Sottile, R.; Valuev, V.; Verkindt, D.; Vey, H.; Wachnik, M.

    1998-02-01

    A transition radiation detector to identify electrons at 90% efficiency with a rejection factor against pions of 10 3 on an area of 2.85 × 2.85 m 2 has been constructed for the NOMAD experiment. Each of its 9 modules includes a 315 plastic foil radiator and a detector plane of 176 vertical straw tubes filled with a xenon-methane gas mixture. Details of the design, construction and operation of the detector are given.

  1. A large area transition radiation detector for the NOMAD experiment

    CERN Document Server

    Bassompierre, Gabriel; Berthet, M; Bertozzi, T; Détraz, C; Dubois, J M; Dumps, Ludwig; Engster, Claude; Fazio, T; Gaillard, G; Gaillard, Jean-Marc; Gouanère, M; Manola-Poggioli, E; Mossuz, L; Mendiburu, J P; Nédélec, P; Palazzini, E; Pessard, H; Petit, P; Petitpas, P; Placci, Alfredo; Sillou, D; Sottile, R; Valuev, V Yu; Verkindt, D; Vey, H; Wachnik, M

    1997-01-01

    A transition radiation detector to identify electrons at 90% efficiency with a rejection factor against pions of 10 3 on an area of 2.85 × 2.85 m 2 has been constructed for the NOMAD experiment. Each of its 9 modules includes a 315 plastic foil radiator and a detector plane of 176 vertical straw tubes filled with a xenon-methane gas mixture. Details of the design, construction and operation of the detector are given.

  2. 76 FR 66660 - Special Conditions: Gulfstream Aerospace LP (GALP) Model G280 Airplane, Operation Without Normal...

    Science.gov (United States)

    2011-10-27

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 25 [Docket No. FAA-2011-1172: Notice No. 25-11-17-SC] Special Conditions: Gulfstream Aerospace LP (GALP) Model G280 Airplane... Aerospace LP (GALP) Model G280 airplane. This airplane will have a novel or unusual design feature...

  3. Serious complications in experiments in which UV doses are effected by using different lamp heights.

    Science.gov (United States)

    Flint, Stephan D; Ryel, Ronald J; Hudelson, Timothy J; Caldwell, Martyn M

    2009-10-06

    Many experiments examining plant responses to enhanced ultraviolet-B radiation (280-315nm) simply compare an enhanced UV-B treatment with ambient UV-B (or no UV-B radiation in most greenhouse and controlled-environment studies). Some more detailed experiments utilize multiple levels of UV-B radiation. A number of different techniques have been used to adjust the UV dose. One common technique is to place racks of fluorescent UV-emitting lamps at different heights above the plant canopy. However, the lamps and associated support structure cast shadows on the plant bed below. We calculated one example of the sequence of shade intervals for two common heights of lamp racks and show the patterns and duration of shade which the plants receive is distributed differently over the course of the day for different heights of the lamp racks. We also conducted a greenhouse experiment with plants (canola, sunflower and maize) grown under unenergized lamp racks suspended at the same two heights above the canopy. Growth characteristics differed in unpredictable ways between plants grown under the two heights of lamp racks. These differences could enhance or obscure potential UV-B effects. Also, differences in leaf mass per unit foliage area, which were observed in this experiment, could contribute to differences in plant UV-B sensitivity. We recommend the use of other techniques for achieving multiple doses of UV-B radiation. These range from simple and inexpensive approaches (e.g., wrapping individual fluorescent tubes in layers of a neutral-density filter such as cheese cloth) to more technical and expensive alternatives (e.g., electronically modulated lamp control systems). These choices should be determined according to the goals of the particular experiment.

  4. Combined radiation damage, annealing, and ageing studies of InGaAsP /InP 1310 nm lasers for the CMS tracker optical links

    CERN Document Server

    Gill, K; Troska, Jan K; Vasey, F

    2002-01-01

    A summary is presented of the combined effects of radiation damage, accelerated annealing and accelerated ageing in 1310 nm InGaAsP/InP multi-quantum-well lasers, the type chosen for use in the CMS Tracker optical links. The radiation damage effects are compared for a variety of radiation sources: /sup 60/Co-gamma, 0.8 MeV (average energy) neutrons, 20 MeV (average energy) neutrons and 300 MeV/c pions that represent important parts of the spectrum of particles that will be encountered in the CMS Tracker. The relative damage factors of the various sources are calculated by comparing the laser threshold current increase due to radiation damage giving approximately=0 : 0.12 : 0.53 : 1 for /sup 60/Co-gamma, approximately =0.8 MeV neutrons, approximately=20 MeV neutrons with respect to 300 MeV/c pions. The effects of bias current and temperature on the annealing were measured and, in all cases, the annealing is proportional to log(annealing time). A bias current of 60 mA increases the annealing, in terms of the ti...

  5. 34 CFR 280.3 - What regulations apply to this program?

    Science.gov (United States)

    2010-07-01

    ... SECONDARY EDUCATION, DEPARTMENT OF EDUCATION MAGNET SCHOOLS ASSISTANCE PROGRAM General § 280.3 What regulations apply to this program? The following regulations apply to the Magnet Schools Assistance Program: (a) The Education Department General Administrative Regulations (EDGAR), 34 CFR parts 75 (Direct...

  6. Fracture Mechanics Testing of Titanium 6AL-4V in AF-M315E

    Science.gov (United States)

    Sampson, J. W.; Martinez, J.; McLean, C.

    2016-01-01

    The Green Propellant Infusion Mission (GPIM) will demonstrate the performance of AF-M315E monopropellant on orbit. Flight certification requires a safe-life analysis of the titanium alloy fuel tank to ensure inherent processing flaws will not cause failure during the design life of the tank. Material property inputs for this analysis require testing to determine the stress intensity factor for environment-assisted cracking (KEAC) of Ti 6Al-4V in combination with the AF-M315E monopropellant. Testing of single-edge notched, or SE(B), specimens representing the bulk tank membrane and weld material were performed in accordance with ASTM E1681. Specimens with fatigue pre-cracks were loaded into test fixtures so that the crack tips were exposed to AF-M315E at 50 C for a duration of 1,000 hours. Specimens that did not fail during exposure were opened to inspect the crack surfaces for evidence of crack growth. The threshold stress intensity value, KEAC, is the highest applied stress intensity that produced neither a failure of the specimen during the exposure nor showed evidence of crack growth. The threshold stress intensity factor for environment-assisted cracking of the Ti 6Al-4V forged tank material was found to be at least 22 ksivin and at least 31 ksivin for the weld material when exposed to AF-M315E monopropellant.

  7. 36 CFR 3.15 - What is the maximum noise level for the operation of a vessel?

    Science.gov (United States)

    2010-07-01

    ... level for the operation of a vessel? 3.15 Section 3.15 Parks, Forests, and Public Property NATIONAL PARK... level for the operation of a vessel? (a) A person may not operate a vessel at a noise level exceeding... vessel is being operated in excess of the noise levels established in paragraph (a) of this section may...

  8. Improving the accuracy of S02 column densities and emission rates obtained from upward-looking UV-spectroscopic measurements of volcanic plumes by taking realistic radiative transfer into account

    Science.gov (United States)

    Kern, Christoph; Deutschmann, Tim; Werner, Cynthia; Sutton, A. Jeff; Elias, Tamar; Kelly, Peter J.

    2012-01-01

    Sulfur dioxide (SO2) is monitored using ultraviolet (UV) absorption spectroscopy at numerous volcanoes around the world due to its importance as a measure of volcanic activity and a tracer for other gaseous species. Recent studies have shown that failure to take realistic radiative transfer into account during the spectral retrieval of the collected data often leads to large errors in the calculated emission rates. Here, the framework for a new evaluation method which couples a radiative transfer model to the spectral retrieval is described. In it, absorption spectra are simulated, and atmospheric parameters are iteratively updated in the model until a best match to the measurement data is achieved. The evaluation algorithm is applied to two example Differential Optical Absorption Spectroscopy (DOAS) measurements conducted at Kilauea volcano (Hawaii). The resulting emission rates were 20 and 90% higher than those obtained with a conventional DOAS retrieval performed between 305 and 315 nm, respectively, depending on the different SO2 and aerosol loads present in the volcanic plume. The internal consistency of the method was validated by measuring and modeling SO2 absorption features in a separate wavelength region around 375 nm and comparing the results. Although additional information about the measurement geometry and atmospheric conditions is needed in addition to the acquired spectral data, this method for the first time provides a means of taking realistic three-dimensional radiative transfer into account when analyzing UV-spectral absorption measurements of volcanic SO2 plumes.

  9. 13 CFR 120.315 - Interest rate and loan limit.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Interest rate and loan limit. 120... Special Purpose Loans Disabled Assistance Loan Program (dal) § 120.315 Interest rate and loan limit. The interest rate on direct DAL loans is three percent. There is an administrative limit of $150,000 on a...

  10. 27 CFR 28.315 - Loss of wine in transit.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Loss of wine in transit..., DEPARTMENT OF THE TREASURY LIQUORS EXPORTATION OF ALCOHOL Losses Wine § 28.315 Loss of wine in transit. The tax on wine withdrawn without payment of tax under this part and which is lost during transportation...

  11. Time-resolved x-ray diffraction studies on the intensity changes of the 5.9 and 5.1 nm actin layer lines from frog skeletal muscle during an isometric tetanus using synchrotron radiation

    International Nuclear Information System (INIS)

    Wakabayashi, K.; Tanaka, H.; Amemiya, Y.; Fujishima, A.; Kobayashi, T.; Hamanaka, T.; Sugi, H.; Mitsui, T.

    1985-01-01

    Time-resolved x-ray diffraction studies have been made on the 5.9- and 5.1-nm actin layer lines from frog skeletal muscles during an isometric tetanus at 6 degrees C, using synchrotron radiation. The integrated intensities of these actin layer lines were found to increase during a tetanus by 30-50% for the 5.9-nm reflection and approximately 70% for the 5.1-nm reflection of the resting values. The intensity increase of both reflections was greater than that taking place in the transition from rest to rigor state. The intensity change of the 5.9-nm reflection preceded those of the myosin 42.9-nm off-meridional reflection and of the equatorial reflections, as well as the isometric tension development. The intensity profile of the 5.9-nm layer line during contraction was found to be different from that observed in the rigor state

  12. Medición y predicción de la radiación solar global UV-B bajo cielos claros y sin nubes

    Directory of Open Access Journals (Sweden)

    Jaime Wright Gilmore

    2016-03-01

    Full Text Available Se presentan mediciones experimentales de la radiación solar ultravioleta en el rango B del espectro solar (UV-B y la radiación ultravioleta en el rango total RUV (UV-A+UV-B en días claros y sin nubes en Heredia, Costa Rica. Se utilizó una radiómetro UV-B, que mide la radiación solar en el rango espectral 280-315 nm, y un radiómetro RUV, que mide la radiación solar en el rango espectral 280-385 nm. La dependencia entre entre UV-B y RUV también fue investigada, y se encontró un excelente grado de asociación entre ambas. Además se detalló que UV-B representa solamente un 5,4% de RUV, a pesar de que UV-B es mil veces más potente que UV-A. Los valores de UV-B medidos in situ fueron comparados con los valores predichos por un modelo atmosférico espectral, el cual utiliza como datos de entrada: la hora del día, la latitud, la altitud, el albedo superficial, la distancia Tierra-Sol, la turbiedad atmosférica y el ozono atmosférico. La comparación entre los valores medidos y predichos dio resultados satisfactorios.

  13. Effects of UV-B radiation on wax biosynthesis

    International Nuclear Information System (INIS)

    Barnes, J.; Paul, N.; Percy, K.; Broadbent, P.; McLaughlin, C.; Mullineaux, P.; Creissen, G.; Wellburn, A.

    1994-01-01

    Two genotypes of tobacco (Nicotiana tabacum L.) were exposed in controlled environment chambers to three levels of biologically effective ultraviolet-B radiation (UV-B BE ; 280-320nm): 0, 4.54 (ambient) and 5.66 (∼ 25% enhancement) kJ m -2 d -1 . After 28 days, the quantity of wax deposited on leaf surfaces was determined gravimetrically; epicuticular wax chemical composition was determined by capillary gas chromatography with homologue assignments confirmed by gas chromatography-mass spectrometry. Leaf wettability was assessed by measuring the contact angle of water droplets placed on leaf surfaces. Tobacco wax consisted of three major hydrocarbon classes: Straight-chain alkanes (C 27 -C 33 ) which comprised ∼ 59% of the hydrocarbon fraction, containing a predominance of odd-chain alkanes with C 31 as the most abundant homologue; branched-chain alkanes (C 25 -C 32 ) which comprised ∼38% of the hydrocarbon fraction with anteiso 3-methyltriacontane (C 30 ) as the predominant homologue; and fatty acids (C 14 -C 18 ) which comprised ∼ 3% of the wax. Exposure to enhanced UV-B radiation reduced the quantity of wax on the adaxial surface of the transgenic mutant, and resulted in marked changes in the chemical composition of the wax on the exposed leaf surface. Enhanced UV-B decreased the quantity of straight-chain alkanes, increased the quantity of branched-chain alkanes and fatty acids, and resulted in shifts toward shorter straight-chain lengths. Furthermore, UV-B-induced changes in wax composition were associated with increased wettability of tobacco leaf surfaces. Overall, the data are consistent with the view that UV-B radiation has a direct and fundamental effect on wax biosynthesis. Relationships between the physico-chemical nature of the leaf surface and sensitivity to UV-B radiation are discussed. (orig.)

  14. UV radiation and primary production in the Antarctic waters

    Digital Repository Service at National Institute of Oceanography (India)

    LokaBharathi, P.A.; Krishnakumari, L.; Bhattathiri, P.M.A.; Chandramohan, D.

    at 683 nm), scalar irradiance (photosynthetically active radiation (PAR), computed primary production (pp), diffuse attenuation coefficient, and UVB (308 and 320 nm) and UVA (340 and 380 nm) radiation and ocean temperature all measured as a function...

  15. Ionizing Radiation Effects on the Noise of 65 nm CMOS Transistors for Pixel Sensor Readout at Extreme Total Dose Levels

    CERN Document Server

    Re, V.; Manghisoni, M.; Riceputi, E.; Traversi, G.; Ratti, L.

    2018-01-01

    This paper is focused on the study of the noise performance of 65 nm CMOS transistors at extremely high total ionizing dose (TID) levels of the order of several hundreds of Mrad(SiO2). Noise measurements are reported and discussed, analyzing radiation effects on 1/ f noise and channel thermal noise. In nMOSFETs, up to 10 Mrad(SiO2), the experimental behavior is consistent with a damage mechanism mainly associ- ated with lateral isolation oxides, and can be modeled by parasitic transistors turning on after irradiation and contributing to the total noise of the device. At very high dose, these parasitic transistors tend to be turned off by negative charge accumulating in interface states and compensating radiation-induced positive charge building up inside thick isolation oxides. Effects associated with ionization and hydrogen transport in spacer oxides may become dominant at 600 Mrad(SiO2) and may explain the observed noise behavior at extremely high TID. The results of this analysis provide an understanding o...

  16. 40 CFR 280.97 - Insurance and risk retention group coverage.

    Science.gov (United States)

    2010-07-01

    ... UNDERGROUND STORAGE TANKS (UST) Financial Responsibility § 280.97 Insurance and risk retention group coverage... information and the brackets deleted: (1) Endorsement Name: [name of each covered location] Address: [address... liability, and exclusions of the policy.] I hereby certify that the wording of this instrument is identical...

  17. Studies on nanosecond 532nm and 355nm and ultrafast 515nm and 532nm laser cutting super-hard materials

    Science.gov (United States)

    Zhang, Jie; Tao, Sha; Wang, Brian; Zhao, Jay

    2017-02-01

    In this paper, micro-processing of three kinds of super-hard materials of poly-crystal diamond (PCD)/tungsten-carbide (WC), CVD-diamond and cubic boron nitride (CNB) has been systematically studied using nanosecond laser (532nm and 355nm), and ultrafast laser (532nm and 515nm). Our purpose is to investigate a full laser micro-cutting solution to achieve a ready-to-use cutting tool insert (CTI). The results show a clean cut with little burns and recasting at edge. The cutting speed of 2-10mm/min depending on thickness was obtained. The laser ablation process was also studied by varying laser parameters (wavelength, pulse width, pulse energy, repetition rate) and tool path to improve cutting speed. Also, studies on material removal efficiency (MRE) of PCD/WC with 355nm-ns and 515nm-fs laser as a function of laser fluence show that 355nm-ns laser is able to achieve higher MRE for PCD and WC. Thus, ultrafast laser is not necessarily used for superhard material cutting. Instead, post-polishing with ultrafast laser can be used to clean cutting surface and improve smoothness.

  18. Photomorphogenic effects of UV-B radiation on plants: consequences for light competition

    International Nuclear Information System (INIS)

    Barnes, P.W.; Ballaré, C.L.; Caldwell, M.M.

    1996-01-01

    A combination of field and labotatory studies were conducted to explore the nature of photomorphogenic effects of ultraviolet-B radiation (UV-B; 280–320 nm) on plant morphology and to evaluate the ecological consequences of these alterations in morphology for interspecific competition. Under laboratory conditions, seedlings of cucumber (Cucumis sativus L.) and tomato (Lycopersicon esculentum Mill.) exhibited appreciable (ca. 50%) and rapid (< 3h) inhibition in hypocotyl elongation in response to UV-B exposure. In cucumber, this inhibition was reversible, occurred without any associated changes in dry matter production and was caused by UV-B incident on the cotyledons and not the stem or growing tip. Inhibition of stem elongation in etiolated tomato seedlings occurred at least 3 h prior to the onset of accumulation of UV-absorbing pigments and monochromatic UV supplied against a background of visible radiation revealed maximum effectiveness in inhibition around 300 nm. Collectively, these findings suggest that a specific, but yet unidentified, UV-B photoreceptor is involved in mediating certain morphological responses to UV-B. For mixtures of wheat (Triticum aestivum L.) and wild oat (Avena fatua L.), a common weedy competitor, supplemental UV-B irradiation in the field differentially altered shoot morphology which resulted in changes in canopy structure, light interception and calculated stand photosynthesis. It is argued that, because of its asymmetrical nature, competition for light can potentially amplify the effects of UV-B on shoot morphology and may, therefore, be an important mechanism by which changes in the solar UV-B spectrum associated with stratospheric ozone reduction could alter the composition and character of terrestrial vegetation

  19. [Chromophoric dissolved organic matter absorption characteristics with relation to fluorescence in typical macrophyte, algae lake zones of Lake Taihu].

    Science.gov (United States)

    Zhang, Yun-lin; Qin, Bo-qiang; Ma, Rong-hua; Zhu, Guang-wei; Zhang, Lu; Chen, Wei-min

    2005-03-01

    Chromophoric dissolved organic matter (CDOM) represents one of the primary light-absorbing species in natural waters and plays a critical in determining the aquatic light field. CDOM shows a featureless absorption spectrum that increases exponentially with decreasing wavelength, which limits the penetration of biologically damaging UV-B radiation (wavelength from 280 to 320 nm) in the water column, thus shielding aquatic organisms. CDOM absorption measurements and their relationship with dissolved organic carbon (DOC), and fluorescence are presented in typical macrophyte and algae lake zone of Lake Taihu based on a field investigation in April in 2004 and lab analysis. Absorption spectral of CDOM was measured from 240 to 800 nm using a Shimadzu UV-2401PC UV-Vis recording spectrophotometer. Fluorescence with an excitation wavelength of 355 nm, an emission wavelength of 450 nm is measured using a Shimadzu 5301 spectrofluorometer. Concentrations of DOC ranged from 6.3 to 17.2 mg/L with an average of 9.08 +/- 2.66 mg/L. CDOM absorption coefficients at 280 nm and 355 nm were in the range of 11.2 - 32.6 m(-1) (average 17.46m(-1) +/- 5.75 m(-1) and 2.4 - 8.3 m(-1) (average 4.17m(-1) +/- 1.47 m(-l)), respectively. The values of the DOC-specific absorption coefficient at 355 nm ranged from 0.31 to 0.64 L x (mg x m)-1. Fluorescence emission at 450 nm, excited at 355 nm, had a mean value of 1.32nm(-1) +/- 0.84 nm(-1). A significant lake zone difference is found in DOC concentration, CDOM absorption coefficient and fluorescence, but not in DOC-specific absorption coefficient and spectral slope coefficient. This regional distribution pattern is in agreement with the location of sources of yellow substance: highest concentrations close to river mouth under the influence of river inflow, lower values in East Lake Taihu. The values of algae lake zone are obvious larger than those of macrophyte lake zone. In Meiliang Bay, CDOM absorption, DOC concentration and fluorescence tend to

  20. Verification Survey of the Building 315 Zero Power Reactor-6 Facility, Argonne National Laboratory-East, Argonne, Illinois

    International Nuclear Information System (INIS)

    W. C. Adams

    2007-01-01

    status surveys (FSS) on Cell 5 that formerly contained the ZPR-6. For the FSS, ANL is following the guidance presented in Draft NUREG/CR-5849, 'Manual for Conducting Radiological Surveys in Support of License Termination', and portions of NUREG-1575, 'Multi-Agency Radiation Survey and Site Investigation Manual (MARSSIM)', as appropriate and DOE Order 5400.5, 'Radiation Protection of the Public and Environment'. (NRC 1992 and 2000 and DOE 1993 and 1995). At the time of the FSS, all contaminated systems and associated components within the scope of the surveyed areas had been removed (ANL 2006). DOE's Argonne Site Office (ASO) is responsible for oversight of the Building 315, Zero Power Reactor-6 remedial action and FSS activities. It is the policy of the DOE to perform independent (third party) verification of FSS activities (DOE 2006). The purpose of these independent verifications (IV) is to confirm that remedial actions have been effective in meeting established and site-specific guidelines and that the documentation accurately and adequately describes the radiological conditions at the site. The Oak Ridge Institute for Science and Education (ORISE) has been designated by the DOE as the organization responsible for this task at ANL, and has been requested to verify the final radiological status of the cleanup activities associated with the Building 315, ZPR-6 Decontamination and Decommissioning Project (ZPR6DDP) at ANL-E

  1. 46 CFR 199.280 - Survival craft embarkation and launching arrangements.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Survival craft embarkation and launching arrangements... Cargo Vessels § 199.280 Survival craft embarkation and launching arrangements. (a) Each lifeboat must be.... (d) All survival craft required for abandonment by the total number of persons on board must be...

  2. Analytical modeling of worldwide medical radiation use

    International Nuclear Information System (INIS)

    Mettler, F.A. Jr.; Davis, M.; Kelsey, C.A.; Rosenberg, R.; Williams, A.

    1987-01-01

    An analytical model was developed to estimate the availability and frequency of medical radiation use on a worldwide basis. This model includes medical and dental x-ray, nuclear medicine, and radiation therapy. The development of an analytical model is necessary as the first step in estimating the radiation dose to the world's population from this source. Since there is no data about the frequency of medical radiation use in more than half the countries in the world and only fragmentary data in an additional one-fourth of the world's countries, such a model can be used to predict the uses of medical radiation in these countries. The model indicates that there are approximately 400,000 medical x-ray machines worldwide and that approximately 1.2 billion diagnostic medical x-ray examinations are performed annually. Dental x-ray examinations are estimated at 315 million annually and approximately 22 million in-vivo diagnostic nuclear medicine examinations. Approximately 4 million radiation therapy procedures or courses of treatment are undertaken annually

  3. Detection of UV Pulse from Insulators and Application in Estimating the Conditions of Insulators

    Science.gov (United States)

    Wang, Jingang; Chong, Junlong; Yang, Jie

    2014-10-01

    Solar radiation in the band of 240-280 nm is absorbed by the ozone layer in the atmosphere, and corona discharges from high-voltage apparatus emit in air mainly in the 230-405 nm range of ultraviolet (UV), so the band of 240-280 nm is called UV Solar Blind Band. When the insulators in a string deteriorate or are contaminated, the voltage distribution along the string will change, which causes the electric fields in the vicinity of insulators change and corona discharge intensifies. An UV pulse detection method to check the conditions of insulators is presented based on detecting the UV pulse among the corona discharge, then it can be confirmed that whether there exist faulty insulators and whether the surface contamination of insulators is severe for the safe operation of power systems. An UV-I Insulator Detector has been developed, and both laboratory tests and field tests have been carried out which demonstrates the practical viability of UV-I Insulator Detector for online monitoring.

  4. Absorption spectrum of DNA for wavelengths greater than 300 nm

    International Nuclear Information System (INIS)

    Sutherland, J.C.; Griffin, K.P.

    1981-01-01

    Although DNA absorption at wavelengths greater than 300 nm is much weaker than that at shorter wavelengths, this absorption seems to be responsible for much of the biological damage caused by solar radiation of wavelengths less than 320 nm. Accurate measurement of the absorption spectrum of DNA above 300 nm is complicated by turbidity characteristic of concentrated solutions of DNA. We have measured the absorption spectra of DNA from calf thymus, Clostridium perfringens, Escherichia coli, Micrococcus luteus, salmon testis, and human placenta using procedures which separate optical density due to true absorption from that due to turbidity. Above 300 nm, the relative absorption of DNA increases as a function of guanine-cytosine content, presumably because the absorption of guanine is much greater than the absorption of adenine at these wavelengths. This result suggests that the photophysical processes which follow absorption of a long-wavelength photon may, on the average, differ from those induced by shorter-wavelength photons. It may also explain the lower quantum yield for the killing of cells by wavelengths above 300 nm compared to that by shorter wavelengths

  5. Magnetic Nature of Light Transmission through a 5-nm Gap.

    Science.gov (United States)

    Yang, Hyosim; Kim, Dai-Sik; Kim, Richard H Joon-Yeon; Ahn, Jae Sung; Kang, Taehee; Jeong, Jeeyoon; Lee, Dukhyung

    2018-02-09

    Slot antennas have been exploited as important building blocks of optical magnetism because their radiations are invoked by the magnetic fields along the axes, as vectorial Babinet principle predicts. However, optical magnetism of a few-nanometer-width slit, for which fascinating applications are found due to the colossal field enhancement but Babinet principle fails due to the nonnegligible thickness, has not been investigated. In this paper, we demonstrated that the magnetic field plays a dominant role in light transmission through a 5-nm slit on a 150-nm-thick gold film. The 5-nm slit was fabricated by atomic layer lithography, and the transmission was investigated for various incident angles by experiment and simulation at 785-nm wavelength. We found that, due to the deep subwavelength gap width, the transmission has the same incident angle dependence as the tangential magnetic field on the metal surface and this magnetic nature of a nanogap holds up to ~100-nm width. Our analysis establishes conditions for nanogap optical magnetism and suggests new possibilities in realizing magnetic-field-driven optical nonlinearities.

  6. 14 CFR 139.315 - Aircraft rescue and firefighting: Index determination.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Aircraft rescue and firefighting: Index... CERTIFICATION OF AIRPORTS Operations § 139.315 Aircraft rescue and firefighting: Index determination. (a) An index is required by paragraph (c) of this section for each certificate holder. The Index is determined...

  7. Alterations in expression of Cat-315 epitope of perineuronal nets during normal ageing, and its modulation by an open-channel NMDA receptor blocker, memantine.

    Science.gov (United States)

    Yamada, Jun; Ohgomori, Tomohiro; Jinno, Shozo

    2017-06-15

    The perineuronal net (PNN), a specialized aggregate of the extracellular matrix, is involved in neuroprotection against oxidative stress, which is now recognized as a major contributor to age-related decline in brain functions. In this study, we investigated the age-related molecular changes of PNNs using monoclonal antibody Cat-315, which recognizes human natural killer-1 (HNK-1) glycan on aggrecan-based PNNs. Western blot analysis showed that the expression levels of Cat-315 epitope in the hippocampus were higher in middle-aged (MA, 12-month-old) mice than in young adult (YA, 2-month-old) mice. Although there were no differences in the expression levels of Cat-315 epitope between old age (OA, 20-month-old) and MA mice, Cat-315 immunoreactivity was also detected in astrocytes of OA mice. To focus on Cat-315 epitope in PNNs, we used YA and MA mice in the following experiments. Optical disector analysis showed that there were no differences in the numbers of Cat-315-positive (Cat-315 + ) PNNs between YA and MA mice. Fluorescence intensity analysis indicated that Cat-315 immunoreactivity in PNNs increased with age in the dorsal hippocampus, which is mainly involved in cognitive functions. Administration of an open-channel blocker of NMDA receptor, memantine, reduced the expression levels of Cat-315 epitope in the hippocampus. Furthermore, the numbers of glutamatergic and GABAergic terminals colocalized with Cat-315 epitope around parvalbumin-positive neurons were decreased by memantine. These findings provide novel insight into the involvement of PNNs in normal brain ageing, and suggest that memantine may counteract the age-related alterations in expression levels of Cat-315 epitope via regulation of its subcellular localization. © 2017 Wiley Periodicals, Inc.

  8. Optical breakdown threshold investigation of 1064 nm laser induced air plasmas

    International Nuclear Information System (INIS)

    Thiyagarajan, Magesh; Thompson, Shane

    2012-01-01

    We present the theoretical and experimental measurements and analysis of the optical breakdown threshold for dry air by 1064 nm infrared laser radiation and the significance of the multiphoton and collisional cascade ionization process on the breakdown threshold measurements over pressures range from 10 to 2000 Torr. Theoretical estimates of the breakdown threshold laser intensities and electric fields are obtained using two distinct theories namely multiphoton and collisional cascade ionization theories. The theoretical estimates are validated by experimental measurements and analysis of laser induced breakdown processes in dry air at a wavelength of 1064 nm by focusing 450 mJ max, 6 ns, 75 MW max high-power 1064 nm IR laser radiation onto a 20 μm radius spot size that produces laser intensities up to 3 - 6 TW/cm 2 , sufficient for air ionization over the pressures of interest ranging from 10 to 2000 Torr. Analysis of the measured breakdown threshold laser intensities and electric fields are carried out in relation with classical and quantum theoretical ionization processes, operating pressures. Comparative analysis of the laser air breakdown results at 1064 nm with corresponding results of a shorter laser wavelength (193 nm) [M. Thiyagarajan and J. E. Scharer, IEEE Trans. Plasma Sci. 36, 2512 (2008)] and a longer microwave wavelength (10 8 nm) [A. D. MacDonald, Microwave Breakdown in Gases (Wiley, New York, 1966)]. A universal scaling analysis of the breakdown threshold measurements provided a direct comparison of breakdown threshold values over a wide range of frequencies ranging from microwave to ultraviolet frequencies. Comparison of 1064 nm laser induced effective field intensities for air breakdown measurements with data calculated based on the collisional cascade and multiphoton breakdown theories is used successfully to determine the scaled collisional microwave portion. The measured breakdown threshold of 1064 nm laser intensities are then scaled to

  9. Improvement in reduced-mode (REM) diodes enable 315 W from 105-μm 0.15-NA fiber-coupled modules

    Science.gov (United States)

    Kanskar, M.; Bao, L.; Chen, Z.; Dawson, D.; DeVito, M.; Dong, W.; Grimshaw, M.; Guan, X.; Hemenway, M.; Martinsen, R.; Urbanek, W.; Zhang, S.

    2018-02-01

    High-power, high-brightness diode lasers have been pursued for many applications including fiber laser pumping, materials processing, solid-state laser pumping, and consumer electronics manufacturing. In particular, 915 nm - and 976 nm diodes are of interest as diode pumps for the kilowatt CW fiber lasers. As a result, there have been many technical thrusts for driving the diode lasers to have both high power and high brightness to achieve high-performance and reduced manufacturing costs. This paper presents our continued progress in the development of high brightness fiber-coupled product platform, nLIGHT element®. In the past decade, the power coupled into a single 105 μm and 0.15 NA fiber has increased by over a factor of ten through improved diode laser brightness and the development of techniques for efficiently coupling multiple emitters. In this paper, we demonstrate further brightness improvement and power-scaling enabled by both the rise in chip brightness/power and the increase in number of chips coupled into a given numerical aperture. We report a new chip technology using x-REM design with brightness as high as 4.3 W/mm-mrad at a BPP of 3 mm-mrad. We also report record 315 W output from a 2×12 nLIGHT element with 105 μm diameter fiber using x-REM diodes and these diodes will allow next generation of fiber-coupled product capable of 250W output power from 105 μm/0.15 NA beam at 915 nm.

  10. Theoretical search for optimal pump parameters for observing spontaneous radiation amplification on the λ=41.8-nm transition of Xe IX in plasma

    International Nuclear Information System (INIS)

    Ivanova, E P; Ivanov, Arkadii L

    2004-01-01

    Based on a collisional-radiative model, an atomic-kinetic calculation of the gains on the 41.8-nm transitions of Pd-like xenon was performed for the plasma produced due to the interaction of a femtosecond laser pulse with gaseous xenon. The gains g(z,τ) averaged over the spatial and temporal coordinates were compared with the known gains which had been measured experimentally in Xe 8+ . The amplification was shown to occur under the conditions of ionisation of the working ions, and the time of output radiation saturation depends on the time of Xe 8+ transformation to higher-ionised ions. Our theoretical investigation enables determining the optimal pump parameters, at which the product of the gain g by the active medium length L is about 20, which exceeds the experimental gL value. (active media)

  11. 40 CFR 280.94 - Allowable mechanisms and combinations of mechanisms.

    Science.gov (United States)

    2010-07-01

    ... requirements of the financial test under this rule, the financial statements of the owner or operator are not consolidated with the financial statements of the guarantor. [53 FR 43370, Oct. 26, 1988, as amended at 58 FR... OPERATORS OF UNDERGROUND STORAGE TANKS (UST) Financial Responsibility § 280.94 Allowable mechanisms and...

  12. Row orientation effect on UV-B, UV-A and PAR solar irradiation components in vineyards at Tuscany, Italy

    Science.gov (United States)

    Grifoni, D.; Carreras, G.; Zipoli, G.; Sabatini, F.; Dalla Marta, A.; Orlandini, S.

    2008-11-01

    Besides playing an essential role in plant photosynthesis, solar radiation is also involved in many other important biological processes. In particular, it has been demonstrated that ultraviolet (UV) solar radiation plays a relevant role in grapevines ( Vitis vinifera) in the production of certain important chemical compounds directly responsible for yield and wine quality. Moreover, the exposure to UV-B radiation (280-320 nm) can affect plant-disease interaction by influencing the behaviour of both pathogen and host. The main objective of this research was to characterise the solar radiative regime of a vineyard, in terms of photosynthetically active radiation (PAR) and UV components. In this analysis, solar spectral UV irradiance components, broadband UV (280-400 nm), spectral UV-B and UV-A (320-400 nm), the biological effective UVBE, as well as the PAR (400-700 nm) component, were all considered. The diurnal patterns of these quantities and the UV-B/PAR and UV-B/UV-A ratios were analysed to investigate the effect of row orientation of the vineyard in combination with solar azimuth and elevation angles. The distribution of PAR and UV irradiance at various heights of the vertical sides of the rows was also studied. The results showed that the highest portion of plants received higher levels of daily radiation, especially the UV-B component. Row orientation of the vines had a pronounced effect on the global PAR received by the two sides of the rows and, to a lesser extent, UV-A and UV-B. When only the diffused component was considered, this geometrical effect was greatly attenuated. UV-B/PAR and UV-A/PAR ratios were also affected, with potential consequences on physiological processes. Because of the high diffusive capacity of the UV-B radiation, the UV-B/PAR ratio was significantly lower on the plant portions exposed to full sunlight than on those in the shade.

  13. 78 FR 49470 - Adrian Jesus Reyna, Inmate Number #80629-280, FCI Bastrop, Federal Correctional Institution, P.O...

    Science.gov (United States)

    2013-08-14

    ... DEPARTMENT OF COMMERCE Bureau of Industry and Security Adrian Jesus Reyna, Inmate Number 80629-280... Privileges On January 27, 2012, in the U.S. District Court, Western District of Texas, Adrian Jesus Reyna.... Until January 27, 2022, Adrian Jesus Reyna, with a last known address at: Inmate Number 80629-280, FCI...

  14. Irradiation behavior of developed radiation resistance optical-fibers and observed optical radiation from their SiO2 cores under reactor irradiation

    International Nuclear Information System (INIS)

    Shikama, Tatsuo; Narui, Minoru; Kayano, Hideo; Kakuta, Tsunemi; Sagawa, Tsutomu; Sanada, Kazuo; Shamoto, Naoki; Uramoto, Toshimasa.

    1994-01-01

    Two kinds of optical fibers were irradiated in a fission reactor, JMTR(Japan Materials Testing Reactor), up to a 1.55x10 19 n/cm 2 fast neutron fluence and a 3.3x10 9 Gy ionizing dose at 370K. Optical transmission spectra were measured in the wavelength range of 450-1750nm, in-situ. Growth of strong optical absorption bands were observed in the range of wavelength shorter than 750nm. In the meantime, the fibers showed good radiation-resistance in the range of wavelength longer than 750nm. Optical radiations were observed from SiO 2 optical fibers under irradiation. A major part of the observed optical radiations is thought to be composed of broad optical radiation in the whole wavelength range studied in the present experiment. This broad optical radiation will be generated by the process of so-called Cerenkov radiation. Also, a sharp optical radiation peak was found at 1270nm on a F-doped fiber. This peak is thought to relate with doped Fluorine ions and ionizing gamma-ray irradiation. (author)

  15. Sudden Exposure to Solar UV-B Radiation Reduces Net CO2 Uptake and Photosystem I Efficiency in Shade-Acclimated Tropical Tree Seedlings1

    Science.gov (United States)

    Krause, G. Heinrich; Grube, Esther; Virgo, Aurelio; Winter, Klaus

    2003-01-01

    Tree seedlings developing in the understory of the tropical forest have to endure short periods of high-light stress when tree-fall gaps are formed, and direct solar radiation, including substantial UV light, reaches the leaves. In experiments simulating the opening of a tree-fall gap, the response of photosynthesis in leaves of shade-acclimated seedlings (Anacardium excelsum, Virola surinamensis, and Calophyllum longifolium) to exposure to direct sunlight (for 20–50 min) was investigated in Panama (9°N). To assess the effects of solar UV-B radiation (280–320 nm), the sunlight was filtered through plastic films that selectively absorbed UV-B or transmitted the complete spectrum. The results document a strong inhibition of CO2 assimilation by sun exposure. Light-limited and light-saturated rates of photosynthetic CO2 uptake by the leaves were affected, which apparently occurred independently of a simultaneous inhibition of potential photosystem (PS) II efficiency. The ambient UV-B light substantially contributed to these effects. The photochemical capacity of PSI, measured as absorbance change at 810 nm in saturating far-red light, was not significantly affected by sun exposure of the seedlings. However, a decrease in the efficiency of P700 photooxidation by far-red light was observed, which was strongly promoted by solar UV-B radiation. The decrease in PSI efficiency may result from enhanced charge recombination in the reaction center, which might represent an incipient inactivation of PSI, but contributes to thermal dissipation of excessive light energy and thereby to photoprotection. PMID:12586898

  16. Characteristics and mutation analysis of Ph-positive leukemia patients with T315I mutation receiving tyrosine kinase inhibitors

    Directory of Open Access Journals (Sweden)

    Xu PP

    2017-09-01

    Full Text Available Peipei Xu,1 Dan Guo,2 Xiaoyan Shao,1 Miaoxin Peng,1 Bing Chen2 1Department of Hematology, Drum Tower Hospital, School of Medicine, Nanjing University, 2Department of Hematology, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, People’s Republic of China Background: TKIs are the first-line treatment for patients with Ph-positive (Ph+ leukemia. However, drug resistance is frequently observed, mainly due to mutations within the breakpoint cluster region-Abelson leukemia virus (BCR-ABL kinase domain. The T315I substitution confers complete resistance to TKIs. The aim of this study was to analyze the clinical characteristics of 17 patients with T315I mutation after TKI treatment and provide a basis for prognosis.Patients and methods: The clinical data of 17 TKI-resistant Ph+ leukemia patients who were found to have a ABL kinase domain mutation from September 2008 to January 2017 were collected. Karyotypes and BCR-ABL fusion gene were analyzed by R-banding and fluorescence in situ hybridization, respectively. Total RNA was extracted by TRIzol reagent, and the ABL kinase domain mutation was detected by direct sequencing.Results: A total of 17 patients reached effective remission including major molecular response and complete cytogenetic response. However, all the patients subsequently developed a T315I mutation after treatment with TKIs. The rate of the BCR-ABL fusion gene in most of the patients who developed the T315I mutation was significantly higher than that before the mutation. At initial diagnosis, patients average platelet count was 149.7×109/L, whereas the average platelet count was only 53.88×109/L after the T315I mutation (P<0.01. The results also showed that the survival time of patients with a high proportion of blast cells or a high number of white blood cells was obviously shortened.Conclusion: Patients platelet count decreased when detected with the T315I mutation compared with the initial

  17. All-fiber femtosecond Cherenkov radiation source

    DEFF Research Database (Denmark)

    Liu, Xiaomin; Lægsgaard, Jesper; Møller, Uffe

    2012-01-01

    -conversion medium, we demonstrate milliwatt-level, stable, and tunable Cherenkov radiation at visible wavelengths 580–630 nm, with pulse duration of sub-160-fs, and the 3 dB spectral bandwidth not exceeding 36 nm. Such an all-fiber Cherenkov radiation source is promising for practical applications in biophotonics...

  18. Effects of solar UVB radiation on growth, flowering and yield of central and southern European maize cultivars (Zea mays L.)

    International Nuclear Information System (INIS)

    Mark, U.; Saile-Mark, M.; Tevini, M.

    1996-01-01

    Different cultivars of maize (Zea mays L.) originating from Central and South Europe were grown from June to September 1994 for 16 weeks in two greenhouses covered with different UVB-absorbing (280-320 nm) plastic foils. Using the ambient UVB radiation level of a southern location (Portugal, 38.7 o N) in one of the greenhouses as an enhanced radiation compared to the reduced radiation in the second greenhouse, an increase of about 12% of UVB was simulated. Six of the eight cultivars examined showed significant reductions in height of up to 18.9% at all developmental stages under increased UVB. In contrast to this, the fresh and dry weight as well as the leaf area was reduced under UVB only at early developmental stages, but with ongoing development the UVB stressed plants caught up. The total content of absorbing compounds of the maize cultivars was completely unaffected by UVB. A flowering delay up to a maximum of 5 days was observed under higher UVB in several cultivars. Probably due to this delay in the cob development the yield decreased to 27.7% under higher UVB at the first harvest after 12 and 14 weeks, whereas at the second harvest after 14 and 16 weeks yield reduction levelled off. (Author)

  19. A monolithic 180 nm CMOS dosimeter for In Vivo Dosimetry medical application

    International Nuclear Information System (INIS)

    Villani, E.G.; Crepaldi, M.; DeMarchi, D.; Gabrielli, A.; Khan, A.; Pikhay, E.; Roizin, Y.; Rosenfeld, A.; Zhang, Z.

    2014-01-01

    The design and development of a monolithic system-on-chip dosimeter fabricated in a standard 180 nm CMOS technology is described. The device is intended for real time In Vivo measurement of dose of radiation during radiotherapy sessions. Owing to its proposed small size, of approximately 1 mm 3 , such solution could be made in-body implantable and, as such, provide a much-enhanced high-resolution, real-time dose measurement for quality assurance in radiation therapy. The device transmits the related information on dose of radiation wirelessly to an external receiver operating in the MICS band. The various phases of this two years project, started in 2011, including the design and development of radiation sensors and integrated RF to perform the readout, will be described. - Highlights: • A novel monolithic CMOS dosimeter of size of 1 mm 3 has been proposed. • Three different fabrications using a CMOS 180 nm technology have been carried out. • Radiation tests results showed a sensitivity of 1 cGy with accuracy better than 3%. • Preliminary RF tests showed that an RF signal is detectable in free air

  20. 21 CFR 173.315 - Chemicals used in washing or to assist in the peeling of fruits and vegetables.

    Science.gov (United States)

    2010-04-01

    ... peeling of fruits and vegetables. 173.315 Section 173.315 Food and Drugs FOOD AND DRUG ADMINISTRATION... used in washing or to assist in the peeling of fruits and vegetables. Chemicals may be safely used to wash or to assist in the peeling of fruits and vegetables in accordance with the following conditions...

  1. Spectral dependence of some UV-B and UV-C responses of Tetrahymena pyriformis irradiated with dye laser generated UV

    International Nuclear Information System (INIS)

    Calkins, John; Colley, Ed; Wheeler, John; Kentucky Univ., Lexington

    1987-01-01

    We have generated UV-B and UV-C radiations using a flashlamp driven tunable dye laser combined with frequency doubling crystals. Using this novel UV source, we have investigated lethality and its modification by growth phase, photoreactivation and caffeine in Tetrahymena pyriformis at 254 nm and from 260-315 nm in 5 nm steps. From the observed responses we have constructed action spectra for lethality, with or without caffeine (a repair inhibitor) and under conditions of photoreactivation. We have also estimated quantum efficiencies for these responses. Our observations suggest that complex changes in response occur at several wavelengths over the UV-C and UV-B regions. (author)

  2. Dose-dependent hepatic transcriptional responses in Atlantic salmon (Salmo salar) exposed to sublethal doses of gamma radiation

    Energy Technology Data Exchange (ETDEWEB)

    Song, You, E-mail: you.song@niva.no [Norwegian University of Life Sciences (NMBU), Faculty of Environmental Science and Technology, Department of Environmental Sciences (IMV), Centre for Environmental Radioactivity - CERAD, P.O. Box 5003, N-1432 Ås (Norway); Norwegian Institute for Water Research (NIVA), Gaustadalléen 21, N-0349 Oslo (Norway); Salbu, Brit; Teien, Hans-Christian; Heier, Lene Sørlie [Norwegian University of Life Sciences (NMBU), Faculty of Environmental Science and Technology, Department of Environmental Sciences (IMV), Centre for Environmental Radioactivity - CERAD, P.O. Box 5003, N-1432 Ås (Norway); Rosseland, Bjørn Olav [Norwegian University of Life Sciences (NMBU), Faculty of Environmental Science and Technology, Department of Environmental Sciences (IMV), Centre for Environmental Radioactivity - CERAD, P.O. Box 5003, N-1432 Ås (Norway); Norwegian University of Life Sciences (NMBU), Department of Ecology and Natural Resource Management, P.O. Box 5003, N-1432 Ås (Norway); Tollefsen, Knut Erik [Norwegian University of Life Sciences (NMBU), Faculty of Environmental Science and Technology, Department of Environmental Sciences (IMV), Centre for Environmental Radioactivity - CERAD, P.O. Box 5003, N-1432 Ås (Norway); Norwegian Institute for Water Research (NIVA), Gaustadalléen 21, N-0349 Oslo (Norway)

    2014-11-15

    Highlights: • First study on early stress responses in salmon exposed to low-dose gamma radiation. • Dramatic dose-dependent transcriptional responses characterized. • Multiple modes of action proposed for gamma radiation. - Abstract: Due to the production of free radicals, gamma radiation may pose a hazard to living organisms. The high-dose radiation effects have been extensively studied, whereas the ecotoxicity data on low-dose gamma radiation is still limited. The present study was therefore performed using Atlantic salmon (Salmo salar) to characterize effects of low-dose (15, 70 and 280 mGy) gamma radiation after short-term (48 h) exposure. Global transcriptional changes were studied using a combination of high-density oligonucleotide microarrays and quantitative real-time reverse transcription polymerase chain reaction (qPCR). Differentially expressed genes (DEGs; in this article the phrase gene expression is taken as a synonym of gene transcription, although it is acknowledged that gene expression can also be regulated, e.g., at protein stability and translational level) were determined and linked to their biological meanings predicted using both Gene Ontology (GO) and mammalian ortholog-based functional analyses. The plasma glucose level was also measured as a general stress biomarker at the organism level. Results from the microarray analysis revealed a dose-dependent pattern of global transcriptional responses, with 222, 495 and 909 DEGs regulated by 15, 70 and 280 mGy gamma radiation, respectively. Among these DEGs, only 34 were commonly regulated by all radiation doses, whereas the majority of differences were dose-specific. No GO functions were identified at low or medium doses, but repression of DEGs associated with GO functions such as DNA replication, cell cycle regulation and response to reactive oxygen species (ROS) were observed after 280 mGy gamma exposure. Ortholog-based toxicity pathway analysis further showed that 15 mGy radiation

  3. Sunbeds (invited paper)

    Energy Technology Data Exchange (ETDEWEB)

    Hawk, J.L.M

    2000-07-01

    Ultraviolet radiation (UVR)-emitting sunbeds for self-tanning purposes have been available for around two decades. Originally claimed to be safe by commercial interests, because new technology enabled the emission of mostly UVA (315-400 nm) radiation, rather than the more profuse UVB (280-315 nm) present with UVA in midday summer or tropical sunlight, these devices have now been demonstrated to have similar deleterious cutaneous effects. However, such effects have taken time to define, and sunbed operators have continued to advocate their equipment as safe, with a tendency to tan without the sunburn characteristic of sunlight exposure; now that it indeed appears that sunbed UVA, along with not inconsiderable amounts of UVB usually also emitted, is similarly damaging to sunlight, a recent move has been to produce lamps emitting truly sunlight-like radiation instead. UVB and UVA both apparently exert their effects mainly through cutaneous cellular DNA damage, probably particularly in the germinative basal cell layer, UVB very likely through direct absorption and UVA more through secondary photosensitisation effects. As a result, sunburn, a tissue repair process, is initiated, along with an immediate tanning effect in those who tan readily; the former reaction, which may vary from subclinical to severe, sometimes leads in excessive instances to a persisting cutaneous hypersensitivity, or very rarely in extreme cases a fatal outcome. Delayed tanning also occurs after UVR exposure, again as a result of cutaneous DNA damage, the latter more marked in the fair-skinned who are perhaps more likely to use sunbeds in the first place. In addition, a sunbed tan usually only mildly protects the skin against later sunlight-induced damage, while irregular patchy tanning, dryness and itching of the skin are also common outcomes, and induction of the unsightly, pruritic polymorphic light eruption and more severe potentially debilitating disorders such as lupus erythematosus are

  4. Sunbeds (invited paper)

    International Nuclear Information System (INIS)

    Hawk, J.L.M.

    2000-01-01

    Ultraviolet radiation (UVR)-emitting sunbeds for self-tanning purposes have been available for around two decades. Originally claimed to be safe by commercial interests, because new technology enabled the emission of mostly UVA (315-400 nm) radiation, rather than the more profuse UVB (280-315 nm) present with UVA in midday summer or tropical sunlight, these devices have now been demonstrated to have similar deleterious cutaneous effects. However, such effects have taken time to define, and sunbed operators have continued to advocate their equipment as safe, with a tendency to tan without the sunburn characteristic of sunlight exposure; now that it indeed appears that sunbed UVA, along with not inconsiderable amounts of UVB usually also emitted, is similarly damaging to sunlight, a recent move has been to produce lamps emitting truly sunlight-like radiation instead. UVB and UVA both apparently exert their effects mainly through cutaneous cellular DNA damage, probably particularly in the germinative basal cell layer, UVB very likely through direct absorption and UVA more through secondary photosensitisation effects. As a result, sunburn, a tissue repair process, is initiated, along with an immediate tanning effect in those who tan readily; the former reaction, which may vary from subclinical to severe, sometimes leads in excessive instances to a persisting cutaneous hypersensitivity, or very rarely in extreme cases a fatal outcome. Delayed tanning also occurs after UVR exposure, again as a result of cutaneous DNA damage, the latter more marked in the fair-skinned who are perhaps more likely to use sunbeds in the first place. In addition, a sunbed tan usually only mildly protects the skin against later sunlight-induced damage, while irregular patchy tanning, dryness and itching of the skin are also common outcomes, and induction of the unsightly, pruritic polymorphic light eruption and more severe potentially debilitating disorders such as lupus erythematosus are

  5. [Influence of cold spot temperature on 253.7 nm resonance spectra line of electrodeless discharge lamps].

    Science.gov (United States)

    Dong, Jin-yang; Zhang, Gui-xin; Wang, Chang-quan

    2012-01-01

    As a kind of new electric light source, electrodeless discharge lamps are of long life, low mercury and non-stroboscopic light. The lighting effect of electrodeless discharge lamps depends on the radiation efficiency of 253.7 nm resonance spectra line to a large extent. The influence of cold temperature on 253.7 nm resonance spectra line has been studied experimentally by atomic emission spectral analysis. It was found that the radiation efficiency of 253.7 nm resonance spectra line is distributed in a nearly normal fashion with the variation of cold spot temperature, in other words, there is an optimum cold spot temperature for an electrodeless discharge lamp. At last, the results of experiments were analyzed through gas discharge theory, which offers guidance to the improvement of lighting effect for electrodeless discharge lamps.

  6. 40 CFR 280.220 - Ownership of an underground storage tank or underground storage tank system or facility or...

    Science.gov (United States)

    2010-07-01

    ... tank or underground storage tank system or facility or property on which an underground storage tank or underground storage tank system is located. 280.220 Section 280.220 Protection of Environment ENVIRONMENTAL... underground storage tank or underground storage tank system or facility or property on which an underground...

  7. Radiation induction of cancer of the skin

    International Nuclear Information System (INIS)

    Fry, R.J.M.; Storer, J.B.; Burns, F.J.

    1985-01-01

    The induction of epidermal tumors was studied using exposures to 25 kV x-rays with or without subsequent exposures to 12-0-tetradeconyl phorbol-13 acetate (TPA) or ultraviolet radiation (uvr) 280-400 nm. Fractionation regimens and total exposure up to 4000R produced no squamous cell carcinomas. When these regimes were followed by TPA an incidence of about 80% was obtained, and incidence of 60% when uvr exposures followed the x-irradiation. A dose-dependent increase in fibrosarcomas was found when x-irradiation was followed by 24 weeks of topical treatment with TPA. These results support the contention that uvr can enhance the expression of cells initiated by x-rays. The experimental evidence is compared with the data from the tinea capitis patients treated with x-rays. In C3HF/He male mice exposed to 50, 100, 150 and 200 rads 137 Cs gamma rays the induction rate for fibrosarcomas was 2.9 x 10 -4 per cGy/per mouse. This result compares with 2.5 x 10 -6 transformations per surviving cell per cGy with 10T1/2 cells that are fibroblasts derived from C3H mice. 16 refs., 1 fig., 1 tab

  8. In Pursuit of Vitamin D in Plants.

    Science.gov (United States)

    Black, Lucinda J; Lucas, Robyn M; Sherriff, Jill L; Björn, Lars Olof; Bornman, Janet F

    2017-02-13

    Vitamin D deficiency is a global concern. Much research has concentrated on the endogenous synthesis of vitamin D in human skin following exposure to ultraviolet-B radiation (UV-B, 280-315 nm). In many regions of the world there is insufficient UV-B radiation during winter months for adequate vitamin D production, and even when there is sufficient UV-B radiation, lifestyles and concerns about the risks of sun exposure may lead to insufficient exposure and to vitamin D deficiency. In these situations, dietary intake of vitamin D from foods or supplements is important for maintaining optimal vitamin D status. Some foods, such as fatty fish and fish liveroils, certain meats, eggs, mushrooms, dairy, and fortified foods, can provide significant amounts of vitamin D when considered cumulatively across the diet. However, little research has focussed on assessing edible plant foods for potential vitamin D content. The biosynthesis of vitamin D in animals, fungi and yeasts is well established; it is less well known that vitamin D is also biosynthesised in plants. Research dates back to the early 1900s, beginning with in vivo experiments showing the anti-rachitic activity of plants consumed by animals with induced rickets, and in vitro experiments using analytical methods with limited sensitivity. The most sensitive, specific and reliable method for measuring vitamin D and its metabolites is by liquid chromatography tandem mass spectrometry (LC-MS/MS). These assays have only recently been customised to allow measurement in foods, including plant materials. This commentary focuses on the current knowledge and research gaps around vitamin D in plants, and the potential of edible plants as an additional source of vitamin D for humans.

  9. Detection of UVR-induced DNA damage in mouse epidermis in vivo using alkaline elution

    International Nuclear Information System (INIS)

    Kinley, J.S.; Moan, J.; Brunborg, G.

    1995-01-01

    Alkaline elution has been used to detect ultraviolet radiation (UVR)-induced DNA damage in the epidermis of C3H/Tif hr/hr mice. This technique detects DNA damage in the form of single-strand breaks and alkali-labile sites (SSB) formed directly by UVA (320-400 nm) or indirectly by UVB (280-320 nm). The latter induces DNA damage such as cyclobutane pyrimidine dimers and pyrimidine-pyrimidone (6-4)-photoproducts, which are then converted into transient SSB by cellular endonucleases, during nucleotide excision repair (NER). (Author)

  10. Status and initial commissioning of a high gain 800 nm SASE FEL

    CERN Document Server

    Tremaine, Aaron M; Murokh, A; Musumeci, P; Pellegrini, C; Rosenzweig, J; Babzien, M; Ben-Zvi, I; Johnson, E; Malone, R; Rakowsky, G; Skaritka, J; Wang, X J; Yu, L H; Van Bibber, K A; Hill, J M; Le Sage, G P; Carr, R; Cornacchia, M; Nuhn, H D; Ruland, R; Nguyen, D C

    2000-01-01

    We describe the status and initial commissioning of the Visible to Infrared SASE Amplifier (VISA) experiment. VISA uses a strong focusing 4 m undulator, the Brookhaven National Laboratory ATF linac with an energy of 72 MeV, and a photoinjector electron source. The VISA fundamental radiation wavelength is near 800 nm and the power expected at saturation is near 60 MW. Power, angular and spectral measurements are planned for the VISA radiation and these results will be analyzed and compared with SASE FEL theory and computer simulation. In addition, the induced electron beam micro-bunching will be measured using coherent transition radiation.

  11. Status and initial commissioning of a high gain 800 nm SASE FEL

    International Nuclear Information System (INIS)

    Tremaine, A.; Frigola, P.; Murokh, A.; Musumeci, P.; Pellegrini, C.; Rosenzweig, J.; Babzien, M.; Ben-Zvi, I.; Johnson, E.; Malone, R.; Rakowsky, G.; Skaritka, J.; Wang, X.J.; Yu, L.H.; Van Bibber, K.A.; Hill, J.M.; Le Sage, G.P.; Carr, R.; Cornacchia, M.; Nuhn, H.-D.; Ruland, R.; Nguyen, D.C.

    2000-01-01

    We describe the status and initial commissioning of the Visible to Infrared SASE Amplifier (VISA) experiment. VISA uses a strong focusing 4 m undulator, the Brookhaven National Laboratory ATF linac with an energy of 72 MeV, and a photoinjector electron source. The VISA fundamental radiation wavelength is near 800 nm and the power expected at saturation is near 60 MW. Power, angular and spectral measurements are planned for the VISA radiation and these results will be analyzed and compared with SASE FEL theory and computer simulation. In addition, the induced electron beam micro-bunching will be measured using coherent transition radiation

  12. Identification of two novel mutations, PSEN1 E280K and PRNP G127S, in a Malaysian family

    Directory of Open Access Journals (Sweden)

    Ch’ng GS

    2015-09-01

    Full Text Available Gaik-Siew Ch’ng,1,* Seong Soo A An,2,* Sun Oh Bae,2 Eva Bagyinszky,2 SangYun Kim3,41Department of Genetics, Kuala Lumpur Hospital, Malaysia; 2Department of Bionano Technology, Gachon University, 3Department of Neurology, Seoul National University College of Medicine, 4Seoul National University Bundang Hospital, South Korea*These authors contributed equally to this workAbstract: Alzheimer’s disease (AD is the most common form of dementia, which can be categorized into two main forms: early onset AD and late onset AD. The genetic background of early onset AD is well understood, and three genes, the APP, PSEN1, and PSEN2 have been identified as causative genes. In the current study, we tested three siblings from Malaysia who were diagnosed with early onset dementia, as well as their available family members. The family history was positive as their deceased father was similarly affected. Patients were tested for mutations in APP, PSEN1, PSEN2, and PRNP. A novel variant, E280K, was discovered in exon 8 of PSEN1 in the three siblings. In silico analyses with SIFT, SNAP, and PolyPhen2 prediction tools and three-dimensional modeling were performed, and the results suggested that the mutation is probably a pathogenic variant. Two additional pathogenic mutations were previously been described for codon 280, E280A, and E280G, which could support the importance of the E280 residue in the PS1 protein contributing to the pathogenic nature of E280K. Additional ten family members were screened for the E280K mutation, and all of them were negative. Six of them presented with a variety of neuropsychiatric symptoms, including learning disabilities, epilepsy, and schizophrenia, while four family members were asymptomatic. A novel PRNP G127S mutation was found in a step-niece of the three siblings harboring the PSEN1 E280K mutation. In silico predictions for PRNP G127S mutation suggested that this might be possibly a damaging variant. Additional studies to

  13. 283-E, 283-W, and 315 [water treatment plant] hazards assessment

    International Nuclear Information System (INIS)

    Sutton, L.N.

    1998-01-01

    This document establishes the technical basis in support of Emergency Planning activities for the 283E and 283W and 315 Chlorine Facilities on the Hanford Site. Through this document, the technical basis for the development of facility specific Emergency Action Levels and the Emergency Planning Zone is demonstrated

  14. Superluminescence of cadmium sulfide crystals under pulse X-ray radiation

    International Nuclear Information System (INIS)

    Pavlovskaya, N.G.; Tarasov, M.D.; Balakin, V.A.; Varava, V.P.; Lobov, S.I.; Surskij, O.K.; Tsukerman, V.A.

    1977-01-01

    Studies were made to elucidate luminescence properties of CdS crystal radiated by short pulses of braking x-ray radiation. Such a radiation causes the appearance of superluminescence. The radiation was carried out at 295 and 170 K, the radiation dose being changed from 3600 to 1600 r/pulse. At the temperature of 295 K light luminescence was registered at the wave length of 528 nm and half-width of 15 nm. While the temperature lowers, the radiation shifts to the range of shorter wave lengths, and a decrease of the spectrum half-width is observed. With the increase of radiation dose the decrease of radiation spectrum half-width is observed. Approximate calculations show that to achieve the spectrum narrowing to 1 nm at room temperature it is necessary to increase radiation dose per pulse 5-6 times

  15. SGR-76 gamma radiation level indicator

    International Nuclear Information System (INIS)

    Chubinskij-Nadezhdin, I.V.

    1978-01-01

    The design of a gamma-radiation level indicator is described; the instrument is part of a mobile radiometric laboratory (MRL). The design of the instrument permits gamma-radiation dose rates recording at 0.2-200 R/hr, and signals on gamma-background levels. The instrument has two separate threshold levels of signalling actuation. The light signalling at the first level is precautionary, and the sound signalling at the second level indicates the necessity of taking a decision as to whether or not the MRL can remain in the gamma-radiation field. Halogenic counters operating in a current mode are used as detectors. The basic error in recording the dose rate amounts to +-25%. Overall dimensions of the instrument 150x280x100 mm; weight less than 2.5 kg

  16. Microbial raw data for UV-C LED disinfection study

    Data.gov (United States)

    U.S. Environmental Protection Agency — This study evaluated ultraviolet (UV) light emitting diodes (LEDs) emitting at 260 nm, 280 nm, and the combination of 260|280 nm together for their efficacy at...

  17. Occupational radiation exposure in nuclear medicine department in Kuwait

    Science.gov (United States)

    Alnaaimi, M.; Alkhorayef, M.; Omar, M.; Abughaith, N.; Alduaij, M.; Salahudin, T.; Alkandri, F.; Sulieman, A.; Bradley, D. A.

    2017-11-01

    Ionizing radiation exposure is associated with eye lens opacities and cataracts. Radiation workers with heavy workloads and poor protection measures are at risk for vision impairment or cataracts if suitable protection measures are not implemented. The aim of this study was to measure and evaluate the occupational radiation exposure in a nuclear medicine (NM) department. The annual average effective doses (Hp[10] and Hp[0.07]) were measured using calibrated thermos-luminescent dosimeters (TLDs; MCP-N [LiF:Mg,Cu,P]). Five categories of staff (hot lab staff, PET physicians, NM physicians, technologists, and nurses) were included. The average annual eye dose (Hp[3]) for NM staff, based on measurements for a typical yearly workload of >7000 patients, was 4.5 mSv. The annual whole body radiation (Hp[10]) and skin doses (Hp[0.07]) were 4.0 and 120 mSv, respectively. The measured Hp(3), Hp(10), and Hp(0.07) doses for all NM staff categories were below the dose limits described in ICRP 2014 in light of the current practice. The results provide baseline data for staff exposure in NM in Kuwait. Radiation dose optimization measures are recommended to reduce NM staff exposure to its minimal value.

  18. Role of DNA damage in ultraviolet (313 nm) inactivation of yeasts Saccharomyces cerevisial

    International Nuclear Information System (INIS)

    Pospelov, M.E.; Ivanova, Eh.V.; Frajkin, G.Ya.

    1984-01-01

    Relative contribution of photoinhibition of cell respiration and DNA damage to lethal effect, caused by ultraviolet (UV) radiation of 313 m in certain yeast strains Saccharomyces cerevisiae, has been studied. It is shown that cell inactivation is mainly conditioned by DNA photodamage. When studying photoreactivation it has been established, that dimers of pyrimidine bases are the main lethal photoproducts, formed in DNA Under the effect of UV-radiation of 313 nm

  19. Measurements of total cross sections between 23 and 280 GeV/c

    International Nuclear Information System (INIS)

    Koehler, P.F.M.

    1975-01-01

    The high precision measurements of the total cross sections for π/sup +-/, K/sup +-/, p, and anti p scattering from H 2 and D 2 were continued with an extension of the energy range from 23 to 280 GeV/c

  20. Comparison of UV-LED and low pressure UV for water disinfection: Photoreactivation and dark repair of Escherichia coli.

    Science.gov (United States)

    Li, Guo-Qiang; Wang, Wen-Long; Huo, Zheng-Yang; Lu, Yun; Hu, Hong-Ying

    2017-12-01

    Studies on ultraviolet light-emitting diode (UV-LED) water disinfection have shown advantages, such as safety, flexible design, and lower starting voltages. However, information about reactivation after UV-LED disinfection is limited, which is an important issue of UV light-based technology. In this study, the photoreactivation and dark repair of Escherichia coli after UV-LEDs and low pressure (LP) UV disinfection were compared. Four UV-LED units, 265 nm, 280 nm, the combination of 265 + 280 (50%), and 265 + 280 (75%) were tested. 265 nm LEDs was more effective than 280 nm LEDs and LP UV lamps for E. coli inactivation. No synergic effect for disinfection was observed from the combination of 265 and 280 nm LEDs. 265 nm LEDs had no different reactivation performances with that of LP UV, while 280 nm LEDs could significantly repress photoreactivation and dark repair at a low irradiation intensity of 6.9 mJ/cm 2 . Furthermore, the UV-induced damage of 280 nm LEDs was less repaired which was determined by endonuclease sensitive site (ESS) assay. The impaired protein activities by 280 nm LEDs might be one of the reasons that inhibited reactivation. A new reactivation rate constant, K max , was introduced into the logistic model to simulate the reactivation data, which showed positive relationship with the maximum survival ratio and was more reasonable to interpret the results of photoreactivation and dark repair. This study revealed the distinct roles of different UV lights in disinfection and reactivation, which is helpful for the future design of UV-LED equipment. Copyright © 2017 Elsevier Ltd. All rights reserved.

  1. Two-photon-excited fluorescence spectroscopy of atomic fluorine at 170 nm

    Science.gov (United States)

    Herring, G. C.; Dyer, Mark J.; Jusinski, Leonard E.; Bischel, William K.

    1988-01-01

    Two-photon-excited fluorescence spectroscopy of atomic fluorine is reported. A doubled dye laser at 286-nm is Raman shifted in H2 to 170 nm (sixth anti-Stokes order) to excite ground-state 2P(0)J fluorine atoms to the 2D(0)J level. The fluorine atoms are detected by one of two methods: observing the fluorescence decay to the 2PJ level or observing F(+) production through the absorption of an additional photon by the excited atoms. Relative two-photon absorption cross sections to and the radiative lifetimes of the 2D(0)J states are measured.

  2. Benefits from the BESSY FEL Higher Harmonic Radiation

    CERN Document Server

    Goldammer, K

    2005-01-01

    In the FEL process, bunching and coherent radiation is produced at the fundamental frequency as well as its higher harmonics. BESSY proposes a linac-based cascaded High-Gain Harmonic-Generation (HGHG) free electron laser (FEL) multi-user facility. The BESSY soft X-ray FEL will be seeded by three lasers spanning the spectral range of 230nm to 460nm. Two to four HGHG stages downconvert the seed wavelength to the desired radiation range of 1.24nm to 51nm using higher harmonic bunching. As a surplus, higher harmonic radiation is intrinsically produced in each FEL stage. Radiation on a higher harmonic of the FEL frequency is of high interest because it yields the possibility to reduce the number of FEL stages. This paper details extensive studies of the higher harmonic content of the BESSY FEL radiation. Important aspects of FEL interaction on higher harmonics as resulting from theory and from numerical simulations are discussed. For the case of the BESSY FEL, methods for improving the harmonic content are present...

  3. Climatic zones of solar radiation of Galicia; Zonas climaticas de radiacion solar de Galicia

    Energy Technology Data Exchange (ETDEWEB)

    Vazquez, M.; Izquierdo, P.; Pose, M.; Prado, M. T.; Santos, J.

    2008-07-01

    The paper shows the results of a research on the solar radiation received in Galicia that allows assigning each one of the 315 Galician municipalities to one of the Climatic Zones of solar radiation, defined in the Spanish Building Technical Code (BTC). It is proposed to complete the assignment of climatic Zones in the BTC with a new zone, named Climatic Zone 0, with the objective to differentiate the geographical areas in Galicia with less than 3.4 kWh/m{sup 2}.day of yearly daily average solar radiation. The study is completed with the realization of a map of the Climate Zones of solar radiation of Galicia. (Author)

  4. Analyses of Alpha-Alpha Elastic Scattering Data in the Energy Range 140 - 280 MeV

    Energy Technology Data Exchange (ETDEWEB)

    Shehadeh, Zuhair F. [Taif University, Taif (Saudi Arabia)

    2017-01-15

    The differential and the reaction cross-sections for 4He-4He elastic scattering data have been nicely obtained at four energies ranging from 140 MeV to 280 MeV (lab system), namely, 140, 160, 198 and 280 MeV, by using a new optical potential with a short-range repulsive core. The treatment has been handled relativistically as υ/c > 0.25 for the two lower energies and υ/c > 0.31 for the two higher ones. In addition to explaining the elastic angular distributions, the adopted potentials accounted for the structure that may exist at angles close to 90◦ , especially for the 198 and the 280-MeV incident energies. No renormalization has been used, and all our potential parameters are new. The necessity of including a short-range repulsive potential term in our real nuclear potential part has been demonstrated. Our results contribute to solving a long-standing problem concerning the nature of the alpha-alpha potential. This is very beneficial in explaining unknown alpha-nucleus and nucleus-nucleus relativistic reactions by using the cluster formalism.

  5. 30 CFR 280.31 - Whom will MMS notify about environmental issues?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Whom will MMS notify about environmental issues... Obligations Under This Part Environmental Issues § 280.31 Whom will MMS notify about environmental issues? (a... submission for approval. (b) In cases where an environmental assessment is to be prepared, the Director will...

  6. 8 CFR 280.12 - Answer and request or order for interview.

    Science.gov (United States)

    2010-01-01

    ... any argument made. If a personal interview is requested, the evidence in opposition to the imposition... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Answer and request or order for interview... IMPOSITION AND COLLECTION OF FINES § 280.12 Answer and request or order for interview. Within 30 days...

  7. Understanding radiation damage on sub-cellular scale using RADAMOL simulation tool

    Czech Academy of Sciences Publication Activity Database

    Štěpán, Václav; Davídková, Marie

    2016-01-01

    Roč. 128, NOV (2016), s. 11-17 ISSN 0969-806X R&D Projects: GA ČR(CZ) GBP108/12/G108; GA MŠk LD12008 Grant - others:GA MŠk(CZ) LM2010005 Institutional support: RVO:61389005 Keywords : charged particles * DNA * proteins * radiation damage * radical attack * water radiolysis Subject RIV: BO - Biophysics Impact factor: 1.315, year: 2016

  8. Lead extraction by selective operation of a nanosecond-pulsed 355nm laser

    Science.gov (United States)

    Herzog, Amir; Bogdan, Stefan; Glikson, Michael; Ishaaya, Amiel A.; Love, Charles

    2016-03-01

    Lead extraction (LE) is necessary for patients who are suffering from a related infection, or in opening venous occlusions that prevent the insertion of additional lead. In severe cases of fibrous encapsulation of the lead within a vein, laser-based cardiac LE has become one of the foremost methods of removal. In cases where the laser radiation (typically at 308 nm wavelength) interacts with the vein wall rather than with the fibrotic lesion, severe injury and subsequent bleeding may occur. Selective tissue ablation was previously demonstrated by a laser operating in the UV regime; however, it requires the use of sensitizers (e.g.: tetracycline). In this study, we present a preliminary examination of efficacy and safety aspects in the use of a nanosecond-pulsed solid-state laser radiation, at 355 nm wavelength, guided in a catheter consisting of optical fibers, in LE. Specifically, we demonstrate a correlation between the tissue elasticity and the catheter advancement rate, in ex-vivo experiments. Our results indicate a selectivity property for specific parameters of the laser radiation and catheter design. The selectivity is attributed to differences in the mechanical properties of the fibrotic tissue and a normal vein wall, leading to a different photomechanical response of the tissue's extracellular matrix. Furthermore, we performed successful in-vivo animal trials, providing a basic proof of concept for using the suggested scheme in LE. Selective operation using a 355 nm laser may reduce the risk of blood vessel perforation as well as the incidence of major adverse events.

  9. Phase-shifted Bragg grating inscription in PMMA microstructured POF using 248 nm UV radiation

    OpenAIRE

    Pereira, L.; Pospori, A.; Antunes, Paulo; Domingues, Maria Fatima; Marques, S.; Bang, Ole; Webb, David J.; Marques, Carlos A.F.

    2017-01-01

    In this work we experimentally validate and characterize the first phase-shifted polymer optical fiber Bragg gratings (PS-POFBGs) produced using a single pulse from a 248 nm krypton fluoride laser. A single-mode poly (methyl methacrylate) optical fiber with a core doped with benzyl dimethyl ketal for photosensitivity improvement was used. A uniform phase mask customized for 850 nm grating inscription was used to inscribe these Bragg structures. The phase shift defect was created directly duri...

  10. Markarian 315: A test case for the active galactic nucleus-merger hypothesis?

    Science.gov (United States)

    Mackenty, John W.; Simkin, Susan M.; Griffiths, Richard E.; Ulvestad, James S.; Wilson, Andrew S.

    1994-01-01

    Using the Hubble Space Telescope (HST) Wide Field/Planetary Camera, (WF/PC) we have detected a diffuse continuum knot in the inner regions of the Seyfert galaxy Markarian 315. This knot may be a remnant nucleus. It is associated with a complex, ringlike structure in both the continuum and ionized gas emission. We have measured the kinematics of the ionized gas in two position angles and find velocities which are consistent with a nonaxisymmetric gravitational disturbance. The galaxy is associated with an extended ionized filament, or tidal tail, and our measurements show that the ionized gas in this feature is redshifted by up to 500 km/s in the line of sight relative to the Seyfert nucleus. This combination of morphological and kinematic features suggests that Mrk 315 has suffered a disruptive, tidal interaction which has significantly influenced regions within 1 kpc of its nucleus.

  11. Epidemiologic study on survival of chronic myeloid leukemia and Ph(+) acute lymphoblastic leukemia patients with BCR-ABL T315I mutation

    DEFF Research Database (Denmark)

    Nicolini, Franck E; Mauro, Michael J; Martinelli, Giovanni

    2009-01-01

    The BCR-ABL T315I mutation represents a major mechanism of resistance to tyrosine kinase inhibitors (TKIs). The objectives of this retrospective observational study were to estimate overall and progression-free survival for chronic myeloid leukemia in chronic-phase (CP), accelerated-phase (AP......), or blastic-phase (BP) and Philadelphia chromosome-positive (Ph)(+) acute lymphoblastic leukemia (ALL) patients with T315I mutation. Medical records of 222 patients from 9 countries were reviewed; data were analyzed using log-rank tests and Cox proportional hazard models. Median age at T315I mutation...

  12. Pixel front-end development in 65 nm CMOS technology

    International Nuclear Information System (INIS)

    Havránek, M; Hemperek, T; Kishishita, T; Krüger, H; Wermes, N

    2014-01-01

    Luminosity upgrade of the LHC (HL-LHC) imposes severe constraints on the detector tracking systems in terms of radiation hardness and capability to cope with higher hit rates. One possible way of keeping track with increasing luminosity is the usage of more advanced technologies. Ultra deep sub-micron CMOS technologies allow a design of complex and high speed electronics with high integration density. In addition, these technologies are inherently radiation hard. We present a prototype of analog pixel front-end integrated circuit designed in 65 nm CMOS technology with applications oriented towards the ATLAS Pixel Detector upgrade. The aspects of ultra deep sub-micron design and performance of the analog pixel front-end circuits will be discussed

  13. Generation of polypeptide-templated gold nanoparticles using ionizing radiation.

    Science.gov (United States)

    Walker, Candace Rae; Pushpavanam, Karthik; Nair, Divya Geetha; Potta, Thrimoorthy; Sutiyoso, Caesario; Kodibagkar, Vikram D; Sapareto, Stephen; Chang, John; Rege, Kaushal

    2013-08-13

    Ionizing radiation, including γ rays and X-rays, are high-energy electromagnetic radiation with diverse applications in nuclear energy, astrophysics, and medicine. In this work, we describe the use of ionizing radiation and cysteine-containing elastin-like polypeptides (C(n)ELPs, where n = 2 or 12 cysteines in the polypeptide sequence) for the generation of gold nanoparticles. In the presence of C(n)ELPs, ionizing radiation doses higher than 175 Gy resulted in the formation of maroon-colored gold nanoparticle dispersions, with maximal absorbance at 520 nm, from colorless metal salts. Visible color changes were not observed in any of the control systems, indicating that ionizing radiation, gold salt solution, and C(n)ELPs were all required for nanoparticle formation. The hydrodynamic diameters of nanoparticles, determined using dynamic light scattering, were in the range of 80-150 nm, while TEM imaging indicated the formation of gold cores 10-20 nm in diameter. Interestingly, C2ELPs formed 1-2 nm diameter gold nanoparticles in the absence of radiation. Our results describe a facile method of nanoparticle formation in which nanoparticle size can be tailored based on radiation dose and C(n)ELP type. Further improvements in these polypeptide-based systems can lead to colorimetric detection of ionizing radiation in a variety of applications.

  14. Absorption of ultraviolet radiation by antarctic phytoplankton

    Energy Technology Data Exchange (ETDEWEB)

    Vernet, M.; Mitchell, B.G. (Univ. of California-San Diego, La Jolla (United States))

    1990-01-09

    Antarctic phytoplankton contain UV-absorbing compounds that may block damaging radiation. Compounds that absorb from 320-340 nm were observed in spectral absorption of both particulates and in methanol extracts of the particulates. The decrease in the total concentration of these UV compounds with respect to chlorophyll a, as measured by the ratio of in vitro absorption at 335 nm to absorption at 665 nm is variable and decreases with depth. We observed up to 5-fold decrease in this ratio for samples within the physically mixes surface layer. The absorption of UV radiation in methanol extracts, which peaks from 320 to 340 nm, may be composed of several compounds. Shifts in peak absorption with depth (for example, from 331 nm at surface to 321 nm at 75 m), may be interpreted as a change in composition. Ratios of protective yellow xanthophylls (diadinoxanthin + diatoxanthin) to photosynthetic fucoxanthin-like pigments have highest values in surface waters. As these pigments also absorb in the near UV, their function might extend to protection as well as utilization of UV radiation for photosynthesis. We document strong absorption in the UV from 320-330 nm for Antarctic marine particulates. Below this region of the solar energy spectrum, absolute energy levels of incident radiation drop off dramatically. Only wavelengths shorter than about 320 nm will be significantly enhanced due to ozone depletion. If the absorption we observed serves a protective role for phytoplankton photosynthesis, it appears the peak band is in the region where solar energy increases rapidly, and not in the region where depletion would cause significant variations in absolute flux.

  15. Soft errors in 10-nm-scale magnetic tunnel junctions exposed to high-energy heavy-ion radiation

    Science.gov (United States)

    Kobayashi, Daisuke; Hirose, Kazuyuki; Makino, Takahiro; Onoda, Shinobu; Ohshima, Takeshi; Ikeda, Shoji; Sato, Hideo; Inocencio Enobio, Eli Christopher; Endoh, Tetsuo; Ohno, Hideo

    2017-08-01

    The influences of various types of high-energy heavy-ion radiation on 10-nm-scale CoFeB-MgO magnetic tunnel junctions with a perpendicular easy axis have been investigated. In addition to possible latent damage, which has already been pointed out in previous studies, high-energy heavy-ion bombardments demonstrated that the magnetic tunnel junctions may exhibit clear flips between their high- and low-resistance states designed for a digital bit 1 or 0. It was also demonstrated that flipped magnetic tunnel junctions still may provide proper memory functions such as read, write, and hold capabilities. These two findings proved that high-energy heavy ions can produce recoverable bit flips in magnetic tunnel junctions, i.e., soft errors. Data analyses suggested that the resistance flips stem from magnetization reversals of the ferromagnetic layers and that each of them is caused by a single strike of heavy ions. It was concurrently found that an ion strike does not always result in a flip, suggesting a stochastic process behind the flip. Experimental data also showed that the flip phenomenon is dependent on the device and heavy-ion characteristics. Among them, the diameter of the device and the linear energy transfer of the heavy ions were revealed as the key parameters. From their dependences, the physical mechanism behind the flip was discussed. It is likely that a 10-nm-scale ferromagnetic disk loses its magnetization due to a local temperature increase induced by a single strike of heavy ions; this demagnetization is followed by a cooling period associated with a possible stochastic recovery process. On the basis of this hypothesis, a simple analytical model was developed, and it was found that the model accounts for the results reasonably well. This model also predicted that magnetic tunnel junctions provide sufficiently high soft-error reliability for use in space, highlighting their advantage over their counterpart conventional semiconductor memories.

  16. Solar Electromagnetic Radiation Study for Solar Cycle 22: Solar Ultraviolet Irradiance, 120 to 300 NM: Report of Working Groups 2 and 3 of SOLERS 22

    Science.gov (United States)

    Rottman, G. J.; Cebula, R. P.; Gillotay, D.; Simon, P. A.

    1996-01-01

    This report summarizes the activities of Working Group 2 and Working Group 3 of the SOLax Electromagnetic Radiation Study for Solar Cycle 22 (SOLERS22) Program. The international (SOLERS22) is Project 1.2 of the Solar-Terrestrial Energy Program (STEP) sponsored by SCOSTEP, a committee of the International Council of Scientific Unions). SOLERS22 is comprised of five Working Groups, each concentrating on a specific wave-length range: WG-1 - visible and infrared, WG-2 - mid-ultraviolet (200 < A < 300 nm), WG-3 - Far-ultraviolet (lambda greater than 100 and lambda less than 200 nanometers), WG-4 - extreme-ultraviolet (lambda greater than 10 and lambda less than 100 nm), and WG-5 - X-ray (lambda greater than 1 and lambda less than 10 nano meters). The overarching goals of SOLERS22 are to: 1) establish daily solar irradiance values in the specified wavelength ranges, 2) consider the evolving solar structures as the cause of temporal variations, and 3) understand the underlying physical processes driving these changes.

  17. Does a leaf absorb radiation in the near infrared (780-900 nm) region? A new approach to quantifying optical reflection, absorption and transmission of leaves.

    Science.gov (United States)

    Merzlyak, Mark N; Chivkunova, Olga B; Melø, T B; Naqvi, K Razi

    2002-01-01

    The following question is addressed here: do healthy leaves absorb, as the spectra published over the last 50 years indicate, some 5-20% of incident radiation in the 780-900 nm region? The answer is found to be negative, and previous findings result from incomplete collection of the transmitted light by the detection system (even when the leaf is placed next to, but outside, the entrance port of an integrating sphere). A simple remedy for this inherent flaw in the experimental arrangement is applied successfully to leaves (of 10 unrelated species) differing in thickness, age and pigment content. The study has shown that, from an optical standpoint, a leaf tissue is a highly scattering material, and the infinite reflectance of a leaf is exceedingly sensitive to trace amounts of absorbing components. It is shown that water contributes, in a thick leaf (Kalanchoe blossfeldiana), an easily detectable signal even in the 780-900 nm region. The practical benefits resulting from improved measurements of leaf spectra are pointed out.

  18. Radiation effects on radiation-hardened KU and KS-4V optical fibres

    International Nuclear Information System (INIS)

    Ivanov, A.A.; Tugarinov, S.N.; Kaschuck, Y.A.; Krasilnikov, A.V.; Bender, S.E.

    1999-01-01

    The aim of this work was to test the un-pretreated and the hardened (H 2 -loaded and pre-irradiated) KS-4V and KU optical fibres in reactor environment by in-situ measurements of both the radiation-induced loss and the luminescence in the visible spectral region. Both the radio-luminescent and the transmission spectra were in-situ detected during irradiation by charge-coupled-device (CCD) linear detector in the visible spectral region of 400 to 700 nm. The radiation induced loss spectra at the fast neutron fluence of 2*10 6 n/cm 2 shows the hardened, H 2 -loading and pre-irradiating effects in the both KU and KS-4V fibres. KU un-pretreated fibre shows a big radiation absorption band of non-bridging oxygen centered at the wavelength of 630 nm. It appears that the KS-4V hardened fibre has a specific point in the loss spectrum in the vicinity of 460 nm. Other measurements were performed, particularly after reactor shutdown and at 3 different neutron fluences with constant neutron flux after restarting

  19. 21 CFR 111.315 - What are the requirements for laboratory control processes?

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What are the requirements for laboratory control... MANUFACTURING, PACKAGING, LABELING, OR HOLDING OPERATIONS FOR DIETARY SUPPLEMENTS Production and Process Control System: Requirements for Laboratory Operations § 111.315 What are the requirements for laboratory control...

  20. Wild-type and A315T mutant TDP-43 exert differential neurotoxicity in a Drosophila model of ALS

    Science.gov (United States)

    Estes, Patricia S.; Boehringer, Ashley; Zwick, Rebecca; Tang, Jonathan E.; Grigsby, Brianna; Zarnescu, Daniela C.

    2011-01-01

    The RNA-binding protein TDP-43 has been linked to amyotrophic lateral sclerosis (ALS) both as a causative locus and as a marker of pathology. With several missense mutations being identified within TDP-43, efforts have been directed towards generating animal models of ALS in mouse, zebrafish, Drosophila and worms. Previous loss of function and overexpression studies have shown that alterations in TDP-43 dosage recapitulate hallmark features of ALS pathology, including neuronal loss and locomotor dysfunction. Here we report a direct in vivo comparison between wild-type and A315T mutant TDP-43 overexpression in Drosophila neurons. We found that when expressed at comparable levels, wild-type TDP-43 exerts more severe effects on neuromuscular junction architecture, viability and motor neuron loss compared with the A315T allele. A subset of these differences can be compensated by higher levels of A315T expression, indicating a direct correlation between dosage and neurotoxic phenotypes. Interestingly, larval locomotion is the sole parameter that is more affected by the A315T allele than wild-type TDP-43. RNA interference and genetic interaction experiments indicate that TDP-43 overexpression mimics a loss-of-function phenotype and suggest a dominant-negative effect. Furthermore, we show that neuronal apoptosis does not require the cytoplasmic localization of TDP-43 and that its neurotoxicity is modulated by the proteasome, the HSP70 chaperone and the apoptosis pathway. Taken together, our findings provide novel insights into the phenotypic consequences of the A315T TDP-43 missense mutation and suggest that studies of individual mutations are critical for elucidating the molecular mechanisms of ALS and related neurodegenerative disorders. PMID:21441568

  1. 308-nm excimer laser for the treatment of alopecia areata.

    Science.gov (United States)

    Al-Mutairi, Nawaf

    2007-12-01

    Alopecia areata is loss of hair from localized or diffuse areas of hair-bearing area of the skin. Recently there are reports of efficacy of the 308-nm excimer radiation for this condition. To study the effect of the 308-nm excimer laser in the treatment of alopecia areata. Eighteen patients with 42 recalcitrant patches (including 1 adult with alopecia totalis) were enrolled in this study. The lesions were treated with the 308-nm excimer laser twice a week for a period of 12 weeks; one lesion on each patient was left as a control for comparison. There were 7 males and 11 females in this study. Regrowth of hair was observed in 17 (41.5%) patches. Thirteen of the 18 lesions in scalp showed a complete regrowth of hair. The extremity regions failed to show a response. Atopic diatheses had an unfavorable effect on the outcome in our patients. The 308-nm excimer laser is an effective therapeutic option for patchy alopecia areata of the scalp and for some cases with patchy alopecia areata of the beard area. It does not work for patchy alopecia areata of the extremities.

  2. Oxidative damage in response to natural levels of UV-B radiation in larvae of the tropical sea urchin Tripneustes gratilla.

    Science.gov (United States)

    Lister, Kathryn Naomi; Lamare, Miles D; Burritt, David J

    2010-01-01

    To assess the effects of UV radiation (280-400nm) on development, oxidative damage and antioxidant defence in larvae of the tropical sea urchin Tripneustes gratilla, a field experiment was conducted at two depths in Aitutaki, Cook Islands (18.85°S, 159.75°E) in May 2008. Compared with field controls (larvae shielded from UV-R but exposed to VIS-radiation), UV-B exposure resulted in developmental abnormality and increases in oxidative damage to proteins (but not lipids) in embryos of T. gratilla held at 1m depth. Results also indicated that larvae had the capacity to increase the activities of protective antioxidant enzymes when exposed to UV-B. The same trends in oxidative damage and antioxidant defence were observed for embryos held at 4m, although the differences were smaller and more variable. In contrast to UV-B exposure, larvae exposed to UV-A only showed no significant increases in abnormality or oxidative damage to lipids and proteins compared with field controls. This was true at both experimental depths. Furthermore, exposure to UV-A did not cause a significant increase in the activities of antioxidants. This study indicates that oxidative stress is an important response of tropical sea urchin larvae to exposure to UV radiation. © 2010 The Authors. Journal Compilation. The American Society of Photobiology.

  3. Broadband terahertz generation using the semiconductor-metal transition in VO2

    Directory of Open Access Journals (Sweden)

    Nicholas A. Charipar

    2016-01-01

    Full Text Available We report the design, fabrication, and characterization of broadband terahertz emitters based on the semiconductor-metal transition in thin film VO2 (vanadium dioxide. With the appropriate geometry, picosecond electrical pulses are generated by illuminating 120 nm thick VO2 with 280 fs pulses from a femtosecond laser. These ultrafast electrical pulses are used to drive a simple dipole antenna, generating broadband terahertz radiation.

  4. Phosphorylation of actin-binding protein (ABP-280; filamin) by tyrosine kinase p56lck modulates actin filament cross-linking.

    Science.gov (United States)

    Pal Sharma, C; Goldmann, Wolfgang H

    2004-01-01

    Actin-binding protein (ABP-280; filamin) is a phosphoprotein present in the periphery of the cytoplasm where it can cross-link actin filaments, associate with lipid membranes, and bind to membrane surface receptors. Given its function and localization in the cell, we decided to investigate the possibility of whether it serves as substrate for p56lck, a lymphocyte-specific member of the src family of protein tyrosine kinases associated with cell surface glycoproteins. The interaction of p56lck with membrane glycoproteins is important for cell development and functional activation. Here, we show that purified p56lck interacts and catalyzes in vitro kinase reactions. Tyrosine phosphorylation by p56lck is restricted to a single peptide of labeled ABP-280 shown by protease digest. The addition of phorbol ester to cells results in the inhibition of phosphorylation of ABP-280 by p56lck. These results show a decrease in phosphorylation suggesting conformationally induced regulation. Dynamic light scattering confirmed increased actin filament cross-linking due to phosphorylation of ABP-280 by p56lck.

  5. The UV-B Photoreceptor UVR8: From Structure to Physiology

    Science.gov (United States)

    Jenkins, Gareth I.

    2014-01-01

    Low doses of UV-B light (280 to 315 nm) elicit photomorphogenic responses in plants that modify biochemical composition, photosynthetic competence, morphogenesis, and defense. UV RESISTANCE LOCUS8 (UVR8) mediates photomorphogenic responses to UV-B by regulating transcription of a set of target genes. UVR8 differs from other known photoreceptors in that it uses specific Trp amino acids instead of a prosthetic chromophore for light absorption during UV-B photoreception. Absorption of UV-B dissociates the UVR8 dimer into monomers, initiating signal transduction through interaction with CONSTITUTIVELY PHOTOMORPHOGENIC1. However, much remains to be learned about the physiological role of UVR8 and its interaction with other signaling pathways, the molecular mechanism of UVR8 photoreception, how the UVR8 protein initiates signaling, how it is regulated, and how UVR8 regulates transcription of its target genes. PMID:24481075

  6. Microstructural characterisation of Ni75Al25 and Ni31.5Al68.5 powder particles produced by gas atomisation

    International Nuclear Information System (INIS)

    García-Escorial, A.; Lieblich, M.

    2014-01-01

    Highlight: ► Successful production of gas atomised Ni75Al25 and Ni31.5Al68.5 powder particles. ► Characterization of the as-solidified microstructure of 75 Al 25 and Ni 31.5 Al 68.5 at.% powder particles below 100 μm in size have been studied. The gas atomised Ni 75 Al 25 powder particles are mainly spherical. The solidification of this alloy is very fast, and its microstructure consists of a dendrite and lamellar structure of partially ordered γ-(Ni), γ′-Ni 3 Al L1 2 phase, and β-NiAl phase. The order increases with the powder particle size. The gas atomised Ni 31.5 Al 68.5 powder particles are also spherical in shape. The microstructure consists of Ni 2 Al 3 dendrites with interdendritic peritectic NiAl 3 and eutectic NiAl 3 + α-Al. The amount of the Ni 2 Al 3 increases as the cooling rate increases. NiAl phase is absent in the gas atomised Ni 31.5 Al 68.5 powder

  7. Development of radiation detection and measurement system - Development of scintillation radiation sensor

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Hee Dong; Kim, Wan [Kyungpook National University, Taegu (Korea); Kim, Do Sung [Taegu University, Taegu (Korea)

    2000-03-01

    We have been fabricated CsI(Tl) scintillation crystals and plastic scintillators for radiation-based measuring equipment. CsI (Tl) single crystals doped with thallium as an activator were grown using the Czochralski method. The crystal structure of grown CsI(Tl) was bcc, and it was confirmed that its lattice constant was 4,568 A. The spectral range of luminescence of CsI(Tl) was 350 {approx} 700 nm independent of thallium concentration, and the fast component of the luminescence was decreased with increasing thallium concentration. The energy resolution of CsI(Tl) scintillator doped with 0.1 mole% thallium was about 9% for 137 Cs {gamma}-rays. The relation formula of {gamma}-ray energy versus energy resolution was ln(FWHM%)=-0.705ln({epsilon})+6.75. The radiation damage of CsI(Tl) increased in proportion to thallium concentration and radiation damage of CsI(Tl) increased in proportion to thallium concentration and radiation dosage, and the irradiated crystals were colored reddish. The radiation induced absorption bands appeared around 355, 425, 520 and 555 nm, and their energy level were about 3.50, 2.88, 2.39 and 2.21 eV. Plastic scintillators were fabricated thermal polymerization method. Those were polymerizing at 120 deg. C, during 72 hours, and annealing at 75 deg. C, during 24 hours. When the concentration of 1st solute was 1.5 wt% and concentration of 2nd solute was 0.01 wt%, the characteristics of scintillation were very excellent. Also 3.0 wt% tetraphenyl lead were loaded to improve the detection efficiency of {gamma}-ray. The range of emission spectrum was 400 {approx} 450nm, and the central peak was 415 nm. The radiation damage was not appear under 1*10{sup 3}Gy, but the color of plastic scintillator was changed to brown, over 1*10{sup 4}Gy exposured. 84 refs., 39 figs. (Author)

  8. 280 GHz Gyro-BWO design study: Final report

    International Nuclear Information System (INIS)

    1988-07-01

    This report summarizes the results of a design study of a 280 GHz Gyro-BWO tunable source. The purpose of this study is to identify and propose viable design alternatives for any significant technological risk associated with building an operational BWO system. The tunable Gyro-BWO system will have three major components: a Gyro-BWO microwave tube, a superconducting magnet, and a power supply/modulator. The design tasks for this study in order of decreasing importance are: design and specification of the superconducting magnet; preliminary design and layout of a Gyro-BWO microwave tube; and specification for the power supply/modulator. 2 refs., 4 figs

  9. Dust Explosion Characteristics of Agglomerated 35 nm and 100 nm Aluminum Particles

    Directory of Open Access Journals (Sweden)

    Hong-Chun Wu

    2010-01-01

    Full Text Available In the experiment, nanoparticles of 35 nm Al and 100 nm Al powders, respectively, formed particles with average sizes of 161 nm and 167 nm in agglomeration. The characteristics of dust cloud explosions with the two powder sizes, 35 nm and 100 nm, revealed considerable differences, as shown here: (dp/dtmax-35 nm = 1254 bar/s, (dp/dtmax-100 nm = 1105 bar/s; Pmax-35 nm = 7.5 bar, Pmax-100 nm = 12.3 bar, and MEC-35 nm = 40 g/m3, MEC-100 nm = 50 g/m3. The reason of Pmax-35 nm value is smaller than Pmax-100 nm may be due to agglomeration. From an analysis of the explosive residue, the study found that nanoparticles of 35 nm Al powder became filamentous strands after an explosion, where most of 100 nm Al nanoparticles maintained a spherical structure, This may be because the initial melting temperature of 35 nm Al is 435.71°C, while that for 100 nm Al is 523.58°C, higher by 87.87°C. This study discovered that explosive property between the 35 nm Al and 100 nm Al powders after agglomeration were different.

  10. Harmonic Content of the BESSY FEL Radiation

    CERN Document Server

    Meseck, Atoosa

    2005-01-01

    BESSY proposes a linac-based cascaded High-Gain Harmonic-Generation (HGHG) free electron laser (FEL) multi-user facility. The BESSY soft X-ray FEL will consist of three undulator lines. The associated tunable lasers will cover the spectral range of 230nm to 460nm. Two to four HGHG stages reduce the seed wavelength to the desired radiation range of 1.24nm < λ < 51nm. The harmonic content of the high-intensity radiator output can be used to reduce the number of necessary HGHG stages. Moreover the higher harmonic content of the final output extends the offered spectral range and thus is of high interest for the user community. In this paper, the higher harmonic content of the final output as well as of the output of several radiators are investigated. The main parameters such as output power, pulse duration and bandwidth as well as their suitability for seeding are discussed.

  11. The BCR-ABLT315I mutation compromises survival in chronic phase chronic myelogenous leukemia patients resistant to tyrosine kinase inhibitors, in a matched pair analysis

    DEFF Research Database (Denmark)

    Nicolini, Franck E; Ibrahim, Amr R; Soverini, Simona

    2013-01-01

    The BCR-ABL T315I mutation confers resistance to currently licensed tyrosine kinase inhibitors in chronic myelogenous leukemia. However, the impact of this mutation on survival in early stages of disease, in chronic phase, has never been detailed. Using matched pair analysis, a cohort of 64...... patients with chronic phase chronic myelogenous leukemia harboring a T315I mutation and resistant to imatinib mesylate was compared to a similar cohort of 53 chronic phase patients resistant to imatinib, but with no detectable T315I mutation, in the pre-ponatinib era. These patients were matched according...... to age at diagnosis, interval between disease diagnosis and start of imatinib treatment, and duration of imatinib therapy. Kaplan-Meier survival analyses demonstrated the significant negative impact of the presence of the T315I mutation on overall survival (since imatinib-resistance: 48.4 months for T315...

  12. Phase-shifted Bragg grating inscription in PMMA microstructured POF using 248 nm UV radiation

    DEFF Research Database (Denmark)

    Pereira, L.; Pospori, A.; Antunes, Paulo

    2017-01-01

    In this work we experimentally validate and characterize the first phase-shifted polymer optical fiber Bragg gratings (PS-POFBGs) produced using a single pulse from a 248 nm krypton fluoride laser. A single-mode poly (methyl methacrylate) optical fiber with a core doped with benzyl dimethyl ketal...... for photosensitivity improvement was used. A uniform phase mask customized for 850 nm grating inscription was used to inscribe these Bragg structures. The phase shift defect was created directly during the grating inscription process by placing a narrow blocking aperture in the center of the UV beam. The produced high...

  13. The Cd 5 3P0 state in the cadmium-photosensitized reaction and the quenching of the resonance radiation at 326.1 nm by nitrogen, carbon monoxide, and carbon dioxide

    International Nuclear Information System (INIS)

    Yamamoto, Shunzo; Takaoka, Motoaki; Tsunashima, Shigeru; Sato, Shin

    1975-01-01

    The emission of the resonance line at 326.1 nm (5 3 P 1 →5 1 S 0 ) and the absorptions of Cd ( 3 P 0 ) at 340.4 nm (5 3 P 0 →5 3 D 1 ) and of Cd ( 3 P 1 ) at 346.6 nm (5 3 P 1 →5 3 D 2 ) have been measured as functions of the pressure of foreign gases at 250 0 C. At the pressures higher than 1 Torr of any rare gas, an equilibrium was established between 5 3 P 1 and 5 3 P 0 states. The efficiency of nitrogen in producing the 5 3 P 0 state from the 5 3 P 1 state was found to be more than 10 3 times those of rare gases. The quenching efficiencies of nitrogen, carbon monoxide, and carbon dioxide for the resonance radiation at 326.1 nm were also measured by using argon as the diluent gas. The half-quenching pressures obtained were 73+-3, 0.47+-0.01, and 0.096+-0.003 Torr for nitrogen, carbon monoxide, and carbon dioxide respectively. (auth.)

  14. Expression of placental protein 14 by the new endometrial cancer cell line MFE-280 in vitro and by endometrial carcinomas in vivo.

    Science.gov (United States)

    Hackenberg, R; Loos, S; Nia, A H; Kunzmann, R; Schulz, K D

    1998-01-01

    MFE-280 endometrial cancer cells express PP14 (placental protein 14) in vitro. PP14 is normally found in the secretory endometrium and in placental tissue. MFE-280 cells, which are tumorigenic in nude mice, were derived from a recurrent, poorly differentiated endometrial carcinoma. The cells were initially grown in suspension culture and later transferred to monolayer cultures. Karyotyping revealed near-diploidy with a complex heterogeneous aberration pattern. MFE-280 cells were positive for the cytokeratins 7, 8, 18 and 19 as well as for vimentin. The expression of PP14 in MFE-280 cells was demonstrated by immunochemistry and reverse transcriptase--polymerase chain reaction. PP14-mRNA was also detected in one out of five endometrial cancer specimen. In tumor tissue the expression of PP14 was not dependent on progestins.

  15. Interactive Effects of Temperature and UV Radiation on Photosynthesis of Chlorella Strains from Polar, Temperate and Tropical Environments: Differential Impacts on Damage and Repair

    Science.gov (United States)

    Wong, Chiew-Yen; Teoh, Ming-Li; Phang, Siew-Moi; Lim, Phaik-Eem; Beardall, John

    2015-01-01

    Global warming and ozone depletion, and the resulting increase of ultraviolet radiation (UVR), have far-reaching impacts on biota, especially affecting the algae that form the basis of the food webs in aquatic ecosystems. The aim of the present study was to investigate the interactive effects of temperature and UVR by comparing the photosynthetic responses of similar taxa of Chlorella from Antarctic (Chlorella UMACC 237), temperate (Chlorella vulgaris UMACC 248) and tropical (Chlorella vulgaris UMACC 001) environments. The cultures were exposed to three different treatments: photosynthetically active radiation (PAR; 400–700 nm), PAR plus ultraviolet-A (320–400 nm) radiation (PAR + UV-A) and PAR plus UV-A and ultraviolet-B (280–320 nm) radiation (PAR + UV-A + UV-B) for one hour in incubators set at different temperatures. The Antarctic Chlorella was exposed to 4, 14 and 20°C. The temperate Chlorella was exposed to 11, 18 and 25°C while the tropical Chlorella was exposed to 24, 28 and 30°C. A pulse-amplitude modulated (PAM) fluorometer was used to assess the photosynthetic response of microalgae. Parameters such as the photoadaptive index (Ek) and light harvesting efficiency (α) were determined from rapid light curves. The damage (k) and repair (r) rates were calculated from the decrease in ΦPSIIeff over time during exposure response curves where cells were exposed to the various combinations of PAR and UVR, and fitting the data to the Kok model. The results showed that UV-A caused much lower inhibition than UV-B in photosynthesis in all Chlorella isolates. The three isolates of Chlorella from different regions showed different trends in their photosynthesis responses under the combined effects of UVR (PAR + UV-A + UV-B) and temperature. In accordance with the noted strain-specific characteristics, we can conclude that the repair (r) mechanisms at higher temperatures were not sufficient to overcome damage caused by UVR in the Antarctic Chlorella strain

  16. Interactive Effects of Temperature and UV Radiation on Photosynthesis of Chlorella Strains from Polar, Temperate and Tropical Environments: Differential Impacts on Damage and Repair.

    Directory of Open Access Journals (Sweden)

    Chiew-Yen Wong

    Full Text Available Global warming and ozone depletion, and the resulting increase of ultraviolet radiation (UVR, have far-reaching impacts on biota, especially affecting the algae that form the basis of the food webs in aquatic ecosystems. The aim of the present study was to investigate the interactive effects of temperature and UVR by comparing the photosynthetic responses of similar taxa of Chlorella from Antarctic (Chlorella UMACC 237, temperate (Chlorella vulgaris UMACC 248 and tropical (Chlorella vulgaris UMACC 001 environments. The cultures were exposed to three different treatments: photosynthetically active radiation (PAR; 400-700 nm, PAR plus ultraviolet-A (320-400 nm radiation (PAR + UV-A and PAR plus UV-A and ultraviolet-B (280-320 nm radiation (PAR + UV-A + UV-B for one hour in incubators set at different temperatures. The Antarctic Chlorella was exposed to 4, 14 and 20°C. The temperate Chlorella was exposed to 11, 18 and 25°C while the tropical Chlorella was exposed to 24, 28 and 30°C. A pulse-amplitude modulated (PAM fluorometer was used to assess the photosynthetic response of microalgae. Parameters such as the photoadaptive index (Ek and light harvesting efficiency (α were determined from rapid light curves. The damage (k and repair (r rates were calculated from the decrease in ΦPSIIeff over time during exposure response curves where cells were exposed to the various combinations of PAR and UVR, and fitting the data to the Kok model. The results showed that UV-A caused much lower inhibition than UV-B in photosynthesis in all Chlorella isolates. The three isolates of Chlorella from different regions showed different trends in their photosynthesis responses under the combined effects of UVR (PAR + UV-A + UV-B and temperature. In accordance with the noted strain-specific characteristics, we can conclude that the repair (r mechanisms at higher temperatures were not sufficient to overcome damage caused by UVR in the Antarctic Chlorella strain

  17. Electron irradiated liquid encapsulated Czochralski grown undoped gallium antimonide studied by positron lifetime spectroscopy and photoluminescence

    International Nuclear Information System (INIS)

    Ma, S K; Lui, M K; Ling, C C; Fung, S; Beling, C D; Li, K F; Cheah, K W; Gong, M; Hang, H S; Weng, H M

    2004-01-01

    Electron irradiated undoped liquid encapsulated Czochralski (LEC) grown GaSb samples were studied by positron lifetime spectroscopy (PLS) and photoluminescence (PL). In addition to the 315 ps component reported in the previous studies, another defect with a lifetime of 280 ps was also identified in the present electron irradiated samples. The bulk lifetime of the GaSb material was found to be 258 ps. The V Ga,280ps and the V Ga,315ps defects were associated with two independent Ga vacancy related defects having different microstructures. The well known 777 meV PL signal (usually band A) was also observed in the electron irradiated undoped GaSb samples. The band A intensity decreases with increasing electron irradiation dosage and it disappears after the 300 deg. C annealing regardless of the irradiation dosage. The origin of the band A signal is also discussed

  18. Evaluating UV-C LED disinfection performance and ...

    Science.gov (United States)

    This study evaluated ultraviolet (UV) light emitting diodes (LEDs) emitting at 260 nm, 280 nm, and the combination of 260|280 nm together for their efficacy at inactivating Escherichia. coli, MS2 coliphage, human adenovirus type 2 (HAdV2), and Bacillus pumilus spores; research included an evaluation of genomic damage. Inactivation by the LEDs was compared with the efficacy of conventional UV sources, the low-pressure (LP) and medium-pressure (MP) mercury vapor lamps. The work also calculated the electrical energy per order of reduction of the microorganisms by the five UV sources.For E. coli, all five UV sources yielded similar inactivation rates. For MS2 coliphage, the 260 nm LED was most effective. For HAdV2 and B. pumilus, the MP UV lamp was significantly more effective than the LP UV and UVC LED sources. When considering electrical energy per order of reduction, the LP UV lamp was the most efficient for E. coli and MS2, and the MPUV and LPUV were equally efficient for HAdV2 and B. pumilus spores. Among the UVC LEDs, the 280 nm LED unit required the least energy per log reduction of E. coli and HAdV2. The 280 nm and 260|280 nm LED units were equally efficient per log reduction of B. pumilus spores, and the 260 nm LED unit required the lowest energy per order of reduction of MS2 coliphage. The combination of the 260 nm and 280 nm UV LED wavelengths was also evaluated for potential synergistic effects. No dual-wavelength synergy was detected for inactivation of

  19. Effectiveness of eye drops protective against ultraviolet radiation.

    Science.gov (United States)

    Daxer, A; Blumthaler, M; Schreder, J; Ettl, A

    1998-01-01

    To test the effectiveness of commercially available ultraviolet (UV)-protective eye drops (8-hydroxy-1-methylchinolinium methylsulphate) which are recommended for protection against both solar and artificial UV radiation. The spectral transmission in the wavelength range from 250 to 500 nm was investigated in 1-nm steps using a high-resolution double monochromator with holographic gratings of 2,400 lines/mm and a 1,000-watt halogen lamp as light source. The transmission spectrum was measured for different values of the layer thickness. The transmission of a liquid layer of about 10 microns, which corresponds to the thickness of the human tear film, shows a cut-off at 290 nm with a transmission of about 25-50% at shorter wavelengths. For wavelengths longer than 290 nm the transmission is higher than 90%. The threshold time ratio for keratitis formation with and without eye drops is above 0.93 considering solar radiation on the earth's surface and above 0.65 considering radiation from arc-welding, respectively. The transmission spectrum of the eye drops under realistic conditions does not show a protective effect against solar UV radiation. However, there exists reduction of UVC radiation in the spectral range typical of artificial UV sources such as arc-welding. We cannot recommend the application of these eye drops as an UV-protective aid against eye damage by solar UV radiation.

  20. Cytogenetic findings from inhabitants of different ages in high background radiation areas of Yangjiang

    International Nuclear Information System (INIS)

    Chen Deqing; Yao Suyan; Zhang Chaoyang

    1997-01-01

    Objective: To explore the relationship between high background radiation and injurious effect on inhabitants. Method: Peripheral blood samples were collected from the inhabitants of 10, 40, 55 and 70 years old in high background radiation areas (HBRA) of Yangjiang, Chromosome preparations were carried out with conventional whole-blood microculture. Results: The percentage of dicentric chromosome with fragments in inhabitants of HBRA was significantly higher than that in control areas (CA) (0.469% vs. 0.315%, P<0.01), and there was an increase in the aberration frequencies with age (or accumulated doses). Conclusion: Chromosome aberration is an extremely sensitive indicator of radiation damage and a good radio-biodosimeter

  1. Interaction of sigma factor sigmaN with Escherichia coli RNA polymerase core enzyme.

    Science.gov (United States)

    Scott, D J; Ferguson, A L; Gallegos, M T; Pitt, M; Buck, M; Hoggett, J G

    2000-12-01

    The equilibrium binding and kinetics of assembly of the DNA-dependent RNA polymerase (RNAP) sigma(N)-holoenzyme has been investigated using biosynthetically labelled 7-azatryptophyl- (7AW)sigma(N). The spectroscopic properties of such 7AW proteins allows their absorbance and fluorescence to be monitored selectively, even in the presence of high concentrations of other tryptophan-containing proteins. The 7AWsigma(N) retained its biological activity in stimulating transcription from sigma(N)-specific promoters, and in in vitro gel electrophoresis assays of binding to core RNAP from Escherichia coli. Furthermore, five Trp-->Ala single mutants of sigma(N) were shown to support growth under conditions of nitrogen limitation, and showed comparable efficiency in activating the sigma(N)-dependent nifH promoter in vivo, indicating that none of the tryptophan residues were essential for activity. The equilibrium binding of 7AWsigma(N) to core RNAP was examined by analytical ultracentrifugation. In sedimentation equilibrium experiments, absorbance data at 315 nm (which reports selectively on the distribution of free and bound 7AWsigma(N)) established that a 1:1 complex was formed, with a dissociation constant lower than 2 microM. The kinetics of the interaction between 7AWsigma(N) and core RNAP was investigated using stopped-flow spectrofluorimetry. A biphasic decrease in fluorescence intensity was observed when samples were excited at 280 nm, whereas only the slower of the two phases was observed at 315 nm. The kinetic data were analysed in terms of a mechanism in which a fast bimolecular association of sigma(N) with core RNAP is followed by a relatively slow isomerization step. The consequences of these findings on the competition between sigma(N) and the major sigma factor, sigma(70), in Escherichia coli are discussed.

  2. Infrared Radiative Properties of Food Materials

    Science.gov (United States)

    Precisely, infrared radiation is electromagnetic radiation whose wavelength is longer than that of visible light, but shorter than that of terahertz radiation and microwaves. The infrared portion of the electromagnetic spectrum spans roughly three orders of magnitude (750 nm to 100 µm) and has been...

  3. Evaluating UV-C LED disinfection performance and investigating potential dual-wavelength synergy

    Science.gov (United States)

    This study evaluated ultraviolet (UV) light emitting diodes (LEDs) emitting at 260 nm, 280 nm, and the combination of 260|280 nm together for their efficacy at inactivating Escherichia. coli, MS2 coliphage, human adenovirus type 2 (HAdV2), and Bacillus pumilus spores; research in...

  4. In Pursuit of Vitamin D in Plants

    Directory of Open Access Journals (Sweden)

    Lucinda J. Black

    2017-02-01

    Full Text Available Vitamin D deficiency is a global concern. Much research has concentrated on the endogenous synthesis of vitamin D in human skin following exposure to ultraviolet‐B radiation (UV‐B, 280315 nm. In many regions of the world there is insufficient UV‐B radiation during winter months for adequate vitamin D production, and even when there is sufficient UV‐B radiation, lifestyles and concerns about the risks of sun exposure may lead to insufficient exposure and to vitamin D deficiency. In these situations, dietary intake of vitamin D from foods or supplements is important for maintaining optimal vitamin D status. Some foods, such as fatty fish and fish liveroils, certain meats, eggs, mushrooms, dairy, and fortified foods, can provide significant amounts of vitamin D when considered cumulatively across the diet. However, little research has focussed on assessing edible plant foods for potential vitamin D content. The biosynthesis of vitamin D in animals, fungi and yeasts is well established; it is less well known that vitamin D is also biosynthesised in plants. Research dates back to the early 1900s, beginning with in vivo experiments showing the anti‐rachitic activity of plants consumed by animals with induced rickets, and in vitro experiments using analytical methods with limited sensitivity. The most sensitive, specific and reliable method for measuring vitamin D and its metabolites is by liquid chromatography tandem mass spectrometry (LC‐MS/MS. These assays have only recently been customised to allow measurement in foods, including plant materials. This commentary focuses on the current knowledge and research gaps around vitamin D in plants, and the potential of edible plants as an additional source of vitamin D for humans.

  5. Four-wave-mixing and nonlinear cavity dumping of 280 picosecond 2nd Stokes pulse at 1.3 μm from Nd:SrMoO4 self-Raman laser

    International Nuclear Information System (INIS)

    Smetanin, S N; Ivleva, L I; Jelínek, M Jr; Kubeček, V; Jelínková, H; Shurygin, A S

    2016-01-01

    The 280 picosecond 2nd Stokes Raman pulses at 1.3 μm were generated directly from the miniature diode-pumped Nd:SrMoO 4 self-Raman laser. Using the 90° phase matching insensitive to the angular mismatch, the self-Raman laser allowed for the achievement of the four-wave-mixing generation of the 2nd Stokes Raman pulse directly in the active Nd:SrMoO 4 crystal at stimulated Raman scattering (SRS) self-conversion of the laser radiation. The passive Cr:YAG Q-switching and nonlinear cavity dumping was used without any phase locking device. (letter)

  6. The System of Nanosecond 280-KeV He+ Pulsed Beam

    International Nuclear Information System (INIS)

    Junphong, P.; Ano, V.; Lekprasert, B.; Suwannakachorn, D.; Thongnopparat, N.; Vilaithong, T.; Chiang Mai U.; Wiedemann, H.; SLAC/SLAC, SSRL

    2006-01-01

    At Fast Neutron Research Facility, the 150 kV-pulses neutron generator is being upgraded to a 280-kV-pulsed-He beam for time-of-flight Rutherford backscattering spectrometry. It involves replacing the existing beam line elements by a multicusp ion source, a 400-kV accelerating tube, 45-double focusing dipole magnet and quadrupole lens. The multicusp ion source is a compact filament-driven of 2.6 cm in diameter and 8 cm in length. The current extracted is 20.4 μ A with 13 kV of extraction voltage and 8.8 kV of Einzel lens voltage. The beam emittance has found to vary between 6-12 mm mrad. The beam transport system has to be redesigned based on the new elements. The important part of a good pulsed beam depends on the pulsing system. The two main parts are the chopper and buncher. An optimized geometry for the 280 keV pulsed helium ion beam will be presented and discussed. The PARMELA code has been used to optimize the space charge effect, resulting in pulse width of less than 2 ns at a target. The calculated distance from a buncher to the target is 4.6 m. Effects of energy spread and phase angle between chopper and buncher have been included in the optimization of the bunch length

  7. 40 CFR 280.108 - Substitution of financial assurance mechanisms by owner or operator.

    Science.gov (United States)

    2010-07-01

    ... alternate financial assurance mechanisms as specified in this subpart, provided that at all times he... 40 Protection of Environment 26 2010-07-01 2010-07-01 false Substitution of financial assurance... OWNERS AND OPERATORS OF UNDERGROUND STORAGE TANKS (UST) Financial Responsibility § 280.108 Substitution...

  8. Temporal variation of optimal UV exposure time over Korea: risks and benefits of surface UV radiation

    Science.gov (United States)

    Lee, Y. G.; Koo, J. H.

    2015-12-01

    Solar UV radiation in a wavelength range between 280 to 400 nm has both positive and negative influences on human body. Surface UV radiation is the main natural source of vitamin D, providing the promotion of bone and musculoskeletal health and reducing the risk of a number of cancers and other medical conditions. However, overexposure to surface UV radiation is significantly related with the majority of skin cancer, in addition other negative health effects such as sunburn, skin aging, and some forms of eye cataracts. Therefore, it is important to estimate the optimal UV exposure time, representing a balance between reducing negative health effects and maximizing sufficient vitamin D production. Previous studies calculated erythemal UV and vitamin-D UV from the measured and modelled spectral irradiances, respectively, by weighting CIE Erythema and Vitamin D3 generation functions (Kazantzidis et al., 2009; Fioletov et al., 2010). In particular, McKenzie et al. (2009) suggested the algorithm to estimate vitamin-D production UV from erythemal UV (or UV index) and determined the optimum conditions of UV exposure based on skin type Ⅱ according to the Fitzpatrick (1988). Recently, there are various demands for risks and benefits of surface UV radiation on public health over Korea, thus it is necessary to estimate optimal UV exposure time suitable to skin type of East Asians. This study examined the relationship between erythemally weighted UV (UVEry) and vitamin D weighted UV (UVVitD) over Korea during 2004-2012. The temporal variations of the ratio (UVVitD/UVEry) were also analyzed and the ratio as a function of UV index was applied in estimating the optimal UV exposure time. In summer with high surface UV radiation, short exposure time leaded to sufficient vitamin D and erythema and vice versa in winter. Thus, the balancing time in winter was enough to maximize UV benefits and minimize UV risks.

  9. Photo-TL in CaSO4:Dy: high exposure dosimetry

    International Nuclear Information System (INIS)

    Caldas, L.V.E.; Mayhugh, M.R.

    1974-01-01

    CaSO 4 :Dy exposed to 10 3 to 10 8 R then annealed in the range 280 to 400 0 C displays little TL in the major dosimetry peak near 200 0 C. Subsequent illumination with 250 nm light reinduces the 200 0 C TL. This radiation-enabled photo-TL is roughly proportional to the square root of the enabling exposure at least to 10 8 R. (auth)

  10. DNA damage in cultured human skin fibroblasts exposed to excimer laser radiation

    Energy Technology Data Exchange (ETDEWEB)

    Rimoldi, D.; Miller, A.C.; Freeman, S.E.; Samid, D. (Department of Pathology, Uniformed Services University of the Health Sciences, Bethesda, MD (USA))

    1991-06-01

    Ultraviolet excimer lasers are being considered for use in a variety of refractive and therapeutic procedures, the long-term biologic consequences of which are unknown. The effect of sublethal doses of 193-nm laser radiation on cellular DNA was examined in cultured human skin fibroblasts. In contrast to 248 nm, treatments with the 193-nm laser radiation below 70 J/m2 did not cause significant pyrimidine dimer formation in the skin cells. This was indicated by the lack of excision repair activities (unscheduled DNA synthesis assay), and further demonstrated by direct analysis of pyrimidine dimers in DNA from irradiated cells. However, a low level of unscheduled DNA synthesis could be detected following irradiation at 193 nm with 70 J/m2. Both the 193-nm and 248-nm radiation were able to induce chromosomal aberrations, as indicated by a micronucleus assay. A dose-dependent increase in micronuclei frequency was observed 48 and 72 h after laser irradiation. These results indicate that exposure of actively replicating human skin fibroblasts to sublethal doses of either 193- or 248-nm laser radiation can result in genotoxicity.

  11. Nitrogen deficiency detection using reflected shortwave radiation from irrigated corn canopies

    International Nuclear Information System (INIS)

    Blackmer, T.M.; Schepers, J.S.; Varvel, G.E.; Walter-Shea, E.A.

    1996-01-01

    Techniques that measure the N status of corn (Zea mays L.) can aid in management decisions that have economic and environmental implications. This study was conducted to identify reflected electromagnetic wavelengths most sensitive to detecting N deficiencies in a corn canopy with the possibility for use as a management tool. Reflected shortwave radiation was measured from an irrigated corn N response trial with four hybrids and five N rates at 0, 40, 80, 120, and 160 kg N ha -1 in 1992 and 0, 50, 100, 150, and 200 kg N ha -1 in 1993. A portable spectroradiometer was used to measure reflected radiation (400-1100 nm in 1992, 350-1050 nm in 1993) from corn canopies at approximately the R5 growth stage. Regression analyses revealed that reflected radiation near 550 and 710 nm was superior to reflected radiation near 450 or 650 nm for detecting N deficiencies. The ratio of light reflectance between 550 and 600 nm to light reflectance between 800 and 900 nm also provided sensitive detection of N stress. In 1993, an inexpensive photometric cell, which has peak sensitivity to light centered at 550 nm, was also used to measure reflected radiation from a corn canopy. Photometric cell readings correlated with relative grain yield (P < 0.001, r 2 = 0.74), but more research will be required to develop procedures to account for varying daylight conditions. These results provide information needed for the development of variable-rate fertilizer N application technology. (author)

  12. Evaluating Ultraviolet Radiation Exposures Determined from TOMS Satellite Data at Sites of Amphibian Declines in Central and South America

    Science.gov (United States)

    Middleton, Elizabeth M.; Smith, David E. (Technical Monitor)

    2000-01-01

    Many amphibian species have experienced substantial population declines, or have disappeared altogether, during the last several decades at a number of amphibian census sites in Central and South America. This study addresses the use of satellite-derived trends in solar ultraviolet-B (UV-B; 280-320 nm) radiation exposures at these sites over the last two decades, and is intended to demonstrate a role for satellite observations in determining whether UV-B radiation is a contributing factor in amphibian declines. UV-B radiation levels at the Earth's surface were derived from the Total Ozone Mapping Spectrometer (TOMS) satellite data, typically acquired daily since 1979. These data were used to calculate the daily erythemal (sunburning) UV-B, or UV-B(sub ery), exposures at the latitude, longitude, and elevation of each of 20 census sites. The annually averaged UV-B(sub ery) dose, as well as the maximum values, have been increasing in both Central and South America, with higher levels received at the Central American sites. The annually averaged UV-B(sub ery) exposures increased significantly from 1979-1998 at all 11 Central American sites examined (r(exp 2) = 0.60 - 0.79; P= 6750 J/sq m*d) to the annual UV-B(sub ery) total has increased from approx. 5% to approx. 15% in Central America over the 19 year period, but actual daily exposures for each species are unknown. Synergy among UV-B radiation and other factors, especially those associated with alterations of water chemistry (e.g., acidification) in aqueous habitats is discussed. These findings justify further research concerning whether UV-B(sub ery) radiation plays a role in amphibian population declines and extinctions.

  13. Photocatalytic ROS production and phototoxicity of titanium dioxide nanoparticles is dependent on solar UV radiation spectrum

    Science.gov (United States)

    Generation of reactive oxygen species (ROS) by titanium dioxide nanoparticles (nano-TiO2) and its consequent phototoxicity to Daphnia magna were measured under different solar UV radiation spectrum by applying a series of optical filters in a solar simulator. Removing UVB (280-32...

  14. Q-switched Nd:YAG/V:YAG microchip 1338 nm laser for laser-induced breakdown spectroscopy

    Science.gov (United States)

    Šulc, Jan; Jelínková, Helena; Nejezchleb, Karel; Škoda, Václav

    2017-12-01

    Q-switched microchip laser emitting radiation at wavelength 1338nm was tested as a radiation source for laser induced breakdown spectroscopy (LIBS). This laser used sandwich crystal which combined in one piece the cooling part (undoped YAG crystal 4mm long), the active laser part (Nd:YAG crystal 12mm long), and the saturable absorber (V:YAG crystal 0.7mm long). The diameter of this crystal was 5 mm. The microchip resonator consisted of dielectric mirrors directly deposited on the monolith crystal surfaces. The pump mirror (HT @ 808 nm, HR @ 1.3 ¹m) was placed on the undoped YAG part. The output coupler (R = 90% @ 1338 nm) was placed on the V:YAG part. The fibre-coupled 808nm pumping laser diode was operating in pulsed regime (rep. rate 250 Hz, pulse width 300 ¹s, pulse energy 6 mJ). Using this pumping, stable and high reproducible Q-switched pulses were generated at wavelength 1338 nm. Pulse length was 6.2 ns (FWHM) and the mean output power was 33mW. The single pulse energy and peak power was 0.13mJ and 21kW, respectively. Laser was operating in fundamental TEM00 mode. The laser radiation was focused on a tested sample using single plano-convex lens (focal length 75 mm). The focal spot radius was 40 ¹m. The corresponding peak-power density was 0.83GW/cm2. The laser induced break-down was successfully reached and corresponding laser-induced plasma spectra were recorded for set of metallic elements (Cu, Ag, Au, In, Zn, Al, Fe, Ni, Cr) and alloys (Sn-Pb solder, duralumin, stainless-steel, brass). To record the spectra, StellarNet BLACK-Comet concave grating CCD-based spectrometer was used without any special collimation optics. Thanks to used laser wavelength far from the detector sensitivity, no special filtering was needed to overcome the CCD dazzling. The constructed laser could significantly improve repletion-rate of up-to-date LIBS devices.

  15. Radiation-induced defects and their recombination processes in the x-ray storage phosphor BaBr2:Eu2+

    International Nuclear Information System (INIS)

    Secu, M; Schweizer, S; Rogulis, U; Spaeth, J-M

    2003-01-01

    The recombination processes in the x-ray storage phosphor BaBr 2 :Eu 2+ were investigated by optical and magneto-optical methods. A structure-sensitive investigation of the defects involved in the recombination processes was performed by detecting the microwave-induced changes in the recombination luminescence in a high magnetic field. F centres as well as V K hole centres are created after x-irradiation at low temperatures. The low-energy recombination band peaking at about 460 nm is due to F-V K centre recombinations, whereas the two high energy bands at 282 and 315 nm are probably due to recombinations of self-trapped excitons

  16. 403 nm cavity ring-down measurements of brown carbon aerosol

    Science.gov (United States)

    Kwon, D.; Grassian, V. H.; Kleiber, P.; Young, M. A.

    2017-12-01

    Atmospheric aerosol influences Earth's climate by absorbing and scattering incoming solar radiation and outgoing terrestrial radiation. One class of secondary organic aerosol (SOA), called brown carbon (BrC), has attracted attention for its wavelength dependent light absorbing properties with absorption coefficients that generally increase from the visible (Vis) to ultraviolet (UV) regions. Here we report results from our investigation of the optical properties of BrC aerosol products from the aqueous phase reaction of ammonium sulfate (AS) with methylglyoxal (MG) using cavity ring-down spectroscopy (CRDS) at 403 nm wavelength. We have measured the optical constants of BrC SOA from the AS/MG reaction as a function of reaction time. Under dry flow conditions, we observed no apparent variation in the BrC refractive index with aging over the course of 22 days. The retrieved BrC optical constants are similar to those of AS with n = 1.52 for the real component. Despite significant UV absorption observed from the bulk BrC solution, the imaginary index value at 403 nm is below our minimum detection limit which puts an upper bound of k as 0.03. These observations are in agreement with results from our recent studies of the light scattering properties of this BrC aerosol.

  17. Fracture Growth Testing of Titanium 6AL-4V in AF-M315E

    Science.gov (United States)

    Sampson, Jeffrey W.; Martinez, Jonathan; McLean, Christopher

    2015-01-01

    The Green Propellant Infusion Mission (GPIM) will demonstrate the performance of AF-M315E monopropellant in orbit. Flight certification requires a safe-life analysis of the titanium alloy fuel tank to ensure inherent flaws will not cause failure during the design life. Material property inputs for this analysis require testing to determine the stress intensity factor for environmentally-assisted cracking (K (sub EAC)) of Ti 6Al-4V in combination with the AF-M315E monopropellant. Testing of single-edge notched specimens SE(B) representing the bulk tank membrane and weld material were performed in accordance with ASTM E1681. Specimens with fatigue pre-cracks were loaded into test fixtures so that the crack tips were exposed to the monopropellant at 50 degrees Centigrade for a duration of 1,000 hours. Specimens that did not fail during exposure were opened to inspect the crack surfaces for evidence of crack growth. The threshold stress intensity value, KEAC, is the highest applied stress intensity that produced neither a failure of the specimen during the exposure nor showed evidence of crack growth. The threshold stress intensity factor of the Ti 6Al-4V forged tank material when exposed to AF-M315E monopropellant was found to be at least 22.0 kilopounds per square inch. The stress intensity factor of the weld material was at least 31.3 kilopounds per square inch.

  18. The development needs of nuclear medicine (NM) in Finland in 1980-84

    International Nuclear Information System (INIS)

    Vauramo, E.; Ahonen, A.; Korkola, O.; Liewendahl, K.; Laensimies, E.; Nyyssoenen, O.; Pietilae, P.; Tervo-Pellikka, R.; Wendelin, H.

    1980-01-01

    In autumn 1978, a task group was set up by the Finnish Hospital League to investigate the development needs of nuclear medicine (NM) in Finland. Clinical chemistry, clinical physiology, diagnostic radiology and hospital physics were represented on the working group. The National Board of Health, the Institute of Radiation Protection and the Finnish Hospital League were also represented. The views of other fields were considered by asking for statements from hospitals, research institutes and medical associations. This report deals with NM procedures on patients. Sample studies (in vitro) belong to the clinical laboratory and they were dealt with only to a minor extent. (orig.) [de

  19. 375-nm ultraviolet-laser based non-line-of-sight underwater optical communication

    KAUST Repository

    Sun, Xiaobin

    2018-05-04

    For circumventing the alignment requirement of line-of-sight (LOS) underwater wireless optical communication (UWOC), we demonstrated a non-line-of-sight (NLOS) UWOC link adequately enhanced using ultraviolet (UV) 375-nm laser. Path loss was chosen as a figure-of-merit for link performance in this investigation, which considers the effects of geometries, water turbidity, and transmission wavelength. The experiments suggest that path loss decreases with smaller azimuth angles, higher water turbidity, and shorter wavelength due in part to enhanced scattering utilizing 375-nm radiation. We highlighted that it is feasible to extend the current findings for long distance NLOS UWOC link in turbid water, such as harbor water.

  20. 65 nm LP/GP mix low cost platform for multi-media wireless and consumer applications

    Science.gov (United States)

    Tavel, B.; Duriez, B.; Gwoziecki, R.; Basso, M. T.; Julien, C.; Ortolland, C.; Laplanche, Y.; Fox, R.; Sabouret, E.; Detcheverry, C.; Boeuf, F.; Morin, P.; Barge, D.; Bidaud, M.; Biénacel, J.; Garnier, P.; Cooper, K.; Chapon, J. D.; Trouiller, Y.; Belledent, J.; Broekaart, M.; Gouraud, P.; Denais, M.; Huard, V.; Rochereau, K.; Difrenza, R.; Planes, N.; Marin, M.; Boret, S.; Gloria, D.; Vanbergue, S.; Abramowitz, P.; Vishnubhotla, L.; Reber, D.; Stolk, P.; Woo, M.; Arnaud, F.

    2006-04-01

    A complete 65 nm CMOS platform, called LP/GP Mix, has been developed employing thick oxide transistor (IO), Low Power (LP) and General Purpose (GP) devices on the same chip. Dedicated to wireless multi-media and consumer applications, this new triple gate oxide platform is low cost (+1mask only) and saves over 35% of dynamic power with the use of the low operating voltage GP. The LP/GP mix shows competitive digital performance with a ring oscillator (FO = 1) speed equal to 7 ps per stage (GP) and 6T-SRAM static power lower than 10 pA/cell (LP). Compatible with mixed-signal design requirements, transistors show high voltage gain, low mismatch factor and low flicker noise. Moreover, to address mobile phone demands, excellent RF performance has been achieved with FT = 160 GHz for LP and 280 GHz for GP nMOS transistors.