WorldWideScience

Sample records for radar beacon forming-i

  1. 33 CFR 149.580 - What are the requirements for a radar beacon?

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false What are the requirements for a radar beacon? 149.580 Section 149.580 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Navigation Miscellaneous § 149.580 What are the requirements for a radar beacon? (a) A radar beacon (RACON...

  2. Mapping plasma structures in the high-latitude ionosphere using beacon satellite, incoherent scatter radar and ground-based magnetometer observations

    T. Neubert

    2002-06-01

    Full Text Available In the autumn of the year 2000, four radio receivers capable of tracking various beacon satellites were set up along the southwestern coast of Greenland. They are used to reconstruct images of the ionospheric plasma density distribution via the tomographic method. In order to test and validate tomographic imaging under the highly variable conditions often prevailing in the high-latitude ionosphere, a time interval was selected when the Sondrestrom incoherent scatter radar conducted measurements of the ionospheric plasma density while the radio receivers tracked a number of beacon satellites. A comparison between two-dimensional images of the plasma density distribution obtained from the radar and the satellite receivers revealed generally good agreement between radar measurements and tomographic images. Observed discrepancies can be attributed to F region plasma patches moving through the field of view with a speed of several hundred meters per second, thereby smearing out the tomographic image. A notable mismatch occurred around local magnetic midnight when a magnetospheric substorm breakup occurred in the vicinity of southwest Greenland (identified from ground-based magnetometer observations. The breakup was associated with a sudden intensification of the westward auroral electrojet which was centered at about 69 and extended up to some 73 corrected geomagnetic latitude. Ground-based magnetometer data may thus have the potential of indicating when the tomographic method is at risk and may fail. We finally outline the application of tomographic imaging, when combined with magnetic field data, to estimate ionospheric Joule heating rates.

  3. Personal Beacon

    2000-01-01

    The MicroPLB (personal locator beacon) is a search and rescue satellite-aided tracking (SARSAT) transmitter. When activated it emits a distress signal to a constellation of internationally operated satellites. The endangered person's identity and location anywhere on Earth is automatically forwarded to central monitoring stations around the world. It is accurate to within just a few meters. The user uses the device to download navigation data from a global positioning satellite receiver. After the download is complete, the MicroPLB functions as a self-locating beacon. Also, it is the only PLB to use a safe battery. In the past, other PLB devices have used batteries that have enough volatility to explode with extreme force. It was developed by Microwave Monolithic, Inc. through SBIR funding from Glenn Research Center and Goddard Space Flight Center.

  4. 75 FR 51093 - Agency Information Collection Activities: Form I-864, Form I-864A, Form I-864EZ, and Form I-864W...

    2010-08-18

    ... DEPARTMENT OF HOMELAND SECURITY U.S. Citizenship and Immigration Services Agency Information... of Homeland Security, U.S. Citizenship and Immigration Services (USCIS) will be submitting the...: Form I-864, Form I-864A, Form I-864EZ, and Form I-864W; U.S. Citizenship and Immigration Services...

  5. Molecular Beacons in Diagnostics

    Tyagi, Sanjay; Kramer, Fred Russell

    2012-01-01

    Recent technical advances have begun to realize the potential of molecular beacons to test for diverse infections in clinical diagnostic laboratories. These include the ability to test for, and quantify, multiple pathogens in the same clinical sample, and to detect antibiotic resistant strains within hours. The design principles of molecular beacons have also spawned a variety of allied technologies.

  6. Auditory evacuation beacons

    Wijngaarden, S.J. van; Bronkhorst, A.W.; Boer, L.C.

    2005-01-01

    Auditory evacuation beacons can be used to guide people to safe exits, even when vision is totally obscured by smoke. Conventional beacons make use of modulated noise signals. Controlled evacuation experiments show that such signals require explicit instructions and are often misunderstood. A new

  7. Recommendation on Transition from Primary/Secondary Radar to Secondary- Only Radar Capability

    1994-10-01

    Radar Beacon Performance Monitor RCIU Remote Control Interface Unit RCL Remote Communications Link R E&D Research, Engineering and Development RML Radar...rate. 3.1.2.5 Maintenance The current LRRs have limited remote maintenance monitoring (RMM) capabilities via the Remote Control Interface Unit ( RCIU ...1, -2 and FPS-20 radars required an upgrade of some of the radar subsystems, namely the RCIU to respond as an RMS and the CD to interface with radar

  8. 8 CFR 204.308 - Where to file Form I-800A or Form I-800.

    2010-01-01

    ... IMMIGRANT PETITIONS Intercountry Adoption of a Convention Adoptee § 204.308 Where to file Form I-800A or... adjudicate the child's application for an immigrant or nonimmigrant visa has jurisdiction to grant final.... When, and if, USCIS adopts electronic, internet-based or other digital means for filing Convention...

  9. COSPAS-SARSAT Beacon Certification Facility

    Federal Laboratory Consortium — EPG's COSPAS-SARSAT Beacon Certification Facility is one of five certification facilities in the world. Formal certifications are available for all beacon types and...

  10. 47 CFR 97.203 - Beacon station.

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Beacon station. 97.203 Section 97.203... SERVICE Special Operations § 97.203 Beacon station. (a) Any amateur station licensed to a holder of a Technician, Technician Plus, General, Advanced or Amateur Extra Class operator license may be a beacon. A...

  11. Simulation of a weather radar display for over-water airborne radar approaches

    Clary, G. R.

    1983-01-01

    Airborne radar approach (ARA) concepts are being investigated as a part of NASA's Rotorcraft All-Weather Operations Research Program on advanced guidance and navigation methods. This research is being conducted using both piloted simulations and flight test evaluations. For the piloted simulations, a mathematical model of the airborne radar was developed for over-water ARAs to offshore platforms. This simulated flight scenario requires radar simulation of point targets, such as oil rigs and ships, distributed sea clutter, and transponder beacon replies. Radar theory, weather radar characteristics, and empirical data derived from in-flight radar photographs are combined to model a civil weather/mapping radar typical of those used in offshore rotorcraft operations. The resulting radar simulation is realistic and provides the needed simulation capability for ongoing ARA research.

  12. The Radar Correlation and Interpolation (C&I) Algorithms Deployed in the ASR-9 Processor Augmentation Card (9PAC)

    Elkin, G

    2001-01-01

    .... The increased processing speed and memory size of the 9PAC hardware made it possible for new surveillance algorithms to be developed in software in order to provide improved primary radar and beacon...

  13. The ANTARES optical beacon system

    Ageron, M.; Aguilar, J.A.; Albert, A.

    2007-01-01

    ANTARES is a neutrino telescope being deployed in the Mediterranean Sea. It consists of a three-dimensional array of photomultiplier tubes that can detect the Cherenkov light induced by charged particles produced in the interactions of neutrinos with the surrounding medium. High angular resolution can be achieved, in particular, when a muon is produced, provided that the Cherenkov photons are detected with sufficient timing precision. Considerations of the intrinsic time uncertainties stemming from the transit time spread in the photomultiplier tubes and the mechanism of transmission of light in sea water lead to the conclusion that a relative time accuracy of the order of 0.5 ns is desirable. Accordingly, different time calibration systems have been developed for the ANTARES telescope. In this article, a system based on Optical Beacons, a set of external and well-controlled pulsed light sources located throughout the detector, is described. This calibration system takes into account the optical properties of sea water, which is used as the detection volume of the ANTARES telescope. The design, tests, construction and first results of the two types of beacons, LED and laser-based, are presented

  14. The ANTARES optical beacon system

    Ageron, M. [CPPM - Centre de Physique des Particules de Marseille, CNRS/IN2P3 et Universite de la Mediterranee, 163 Avenue de Luminy, Case 902, 13288 Marseille Cedex 9 (France); Aguilar, J.A. [IFIC - Instituto de Fisica Corpuscular, Edificios de Investigacion de Paterna, CSIC - Universitat de Valencia, Apdo. de Correos 22085, 46071 Valencia (Spain)]. E-mail: J.A.Aguilar@ific.uv.es; Albert, A. [GRPHE - Groupe de Recherche en Physique des Hautes Energies, Universite de Haute Alsace, 61 Rue Albert Camus, 68093 Mulhouse Cedex (France)) (and others)

    2007-08-11

    ANTARES is a neutrino telescope being deployed in the Mediterranean Sea. It consists of a three-dimensional array of photomultiplier tubes that can detect the Cherenkov light induced by charged particles produced in the interactions of neutrinos with the surrounding medium. High angular resolution can be achieved, in particular, when a muon is produced, provided that the Cherenkov photons are detected with sufficient timing precision. Considerations of the intrinsic time uncertainties stemming from the transit time spread in the photomultiplier tubes and the mechanism of transmission of light in sea water lead to the conclusion that a relative time accuracy of the order of 0.5 ns is desirable. Accordingly, different time calibration systems have been developed for the ANTARES telescope. In this article, a system based on Optical Beacons, a set of external and well-controlled pulsed light sources located throughout the detector, is described. This calibration system takes into account the optical properties of sea water, which is used as the detection volume of the ANTARES telescope. The design, tests, construction and first results of the two types of beacons, LED and laser-based, are presented.

  15. The ANTARES optical beacon system

    Ageron, M.; Aguilar, J. A.; Albert, A.; Ameli, F.; Anghinolfi, M.; Anton, G.; Anvar, S.; Ardellier-Desages, F.; Aslanides, E.; Aubert, J.-J.; Auer, R.; Barbarito, E.; Basa, S.; Battaglieri, M.; Becherini, Y.; Beltramelli, J.; Bertin, V.; Bigi, A.; Billault, M.; Blaes, R.; de Botton, N.; Bouwhuis, M. C.; Bradbury, S. M.; Bruijn, R.; Brunner, J.; Burgio, G. F.; Busto, J.; Cafagna, F.; Caillat, L.; Calzas, A.; Capone, A.; Caponetto, L.; Carmona, E.; Carr, J.; Cartwright, S. L.; Castel, D.; Castorina, E.; Cavasinni, V.; Cecchini, S.; Ceres, A.; Charvis, P.; Chauchot, P.; Chiarusi, T.; Circella, M.; Colnard, C.; Compère, C.; Coniglione, R.; Cottini, N.; Coyle, P.; Cuneo, S.; Cussatlegras, A.-S.; Damy, G.; van Dantzig, R.; de Bonis, G.; de Marzo, C.; de Vita, R.; Dekeyser, I.; Delagnes, E.; Denans, D.; Deschamps, A.; Destelle, J.-J.; Dinkespieler, B.; Distefano, C.; Donzaud, C.; Drogou, J.-F.; Druillole, F.; Durand, D.; Ernenwein, J.-P.; Escoffier, S.; Falchini, E.; Favard, S.; Fehr, F.; Feinstein, F.; Ferry, S.; Fiorello, C.; Flaminio, V.; Fratini, K.; Fuda, J.-L.; Galeotti, S.; Gallone, J.-M.; Giacomelli, G.; Girard, N.; Gojak, C.; Goret, Ph.; Graf, K.; Hallewell, G.; Harakeh, M. N.; Hartmann, B.; Heijboer, A.; Heine, E.; Hello, Y.; Hernández-Rey, J. J.; Hößl, J.; Hoffman, C.; Hogenbirk, J.; Hubbard, J. R.; Jaquet, M.; Jaspers, M.; de Jong, M.; Jouvenot, F.; Kalantar-Nayestanaki, N.; Kappes, A.; Karg, T.; Katz, U.; Keller, P.; Kok, E.; Kok, H.; Kooijman, P.; Kopper, C.; Korolkova, E. V.; Kouchner, A.; Kretschmer, W.; Kruijer, A.; Kuch, S.; Kudryavstev, V. A.; Lagier, P.; Lahmann, R.; Lamanna, G.; Lamare, P.; Lambard, G.; Languillat, J.-C.; Laschinsky, H.; Lavalle, J.; Le Guen, Y.; Le Provost, H.; Le van Suu, A.; Lefèvre, D.; Legou, T.; Lelaizant, G.; Lim, G.; Lo Presti, D.; Loehner, H.; Loucatos, S.; Louis, F.; Lucarelli, F.; Lyashuk, V.; Marcelin, M.; Margiotta, A.; Masullo, R.; Mazéas, F.; Mazure, A.; McMillan, J. E.; Megna, R.; Melissas, M.; Migneco, E.; Milovanovic, A.; Mongelli, M.; Montaruli, T.; Morganti, M.; Moscoso, L.; Musumeci, M.; Naumann-Godo, M.; Naumann, C.; Niess, V.; Noble, T.; Olivetto, C.; Ostasch, R.; Palanque-Delabrouille, N.; Payre, P.; Peek, H.; Perez, A.; Petta, C.; Piattelli, P.; Pillet, R.; Pineau, J.-P.; Poinsignon, J.; Popa, V.; Pradier, T.; Racca, C.; Randazzo, N.; van Randwijk, J.; Real, D.; van Rens, B.; Réthoré, F.; Rewiersma, P.; Riccobene, G.; Rigaud, V.; Ripani, M.; Roca, V.; Roda, C.; Rolin, J. F.; Rose, H. J.; Rostovtsev, A.; Roux, J.; Ruppi, M.; Russo, G. V.; Rusydi, G.; Salesa, F.; Salomon, K.; Sapienza, P.; Schmitt, F.; Schuller, J.-P.; Shanidze, R.; Sokalski, I.; Spona, T.; Spurio, M.; van der Steenhoven, G.; Stolarczyk, T.; Streeb, K.; Sulak, L.; Taiuti, M.; Tamburini, C.; Tao, C.; Terreni, G.; Thompson, L. F.; Urbano, F.; Valdy, P.; Valente, V.; Vallage, B.; Vaudaine, G.; Venekamp, G.; Verlaat, B.; Vernin, P.; de Vries-Uiterweerd, G.; van Wijk, R.; Wijnker, G.; de Witt Huberts, P.; Wobbe, G.; de Wolf, E.; Yao, A.-F.; Zaborov, D.; Zaccone, H.; Zornoza, J. D.; Zúñiga, J.

    2007-08-01

    ANTARES is a neutrino telescope being deployed in the Mediterranean Sea. It consists of a three-dimensional array of photomultiplier tubes that can detect the Cherenkov light induced by charged particles produced in the interactions of neutrinos with the surrounding medium. High angular resolution can be achieved, in particular, when a muon is produced, provided that the Cherenkov photons are detected with sufficient timing precision. Considerations of the intrinsic time uncertainties stemming from the transit time spread in the photomultiplier tubes and the mechanism of transmission of light in sea water lead to the conclusion that a relative time accuracy of the order of 0.5 ns is desirable. Accordingly, different time calibration systems have been developed for the ANTARES telescope. In this article, a system based on Optical Beacons, a set of external and well-controlled pulsed light sources located throughout the detector, is described. This calibration system takes into account the optical properties of sea water, which is used as the detection volume of the ANTARES telescope. The design, tests, construction and first results of the two types of beacons, LED and laser-based, are presented.

  16. Searching for Cost-Optimized Interstellar Beacons

    Benford, Gregory; Benford, James; Benford, Dominic

    2010-06-01

    What would SETI beacon transmitters be like if built by civilizations that had a variety of motives but cared about cost? In a companion paper, we presented how, for fixed power density in the far field, a cost-optimum interstellar beacon system could be built. Here, we consider how we should search for a beacon if it were produced by a civilization similar to ours. High-power transmitters could be built for a wide variety of motives other than the need for two-way communication; this would include beacons built to be seen over thousands of light-years. Extraterrestrial beacon builders would likely have to contend with economic pressures just as their terrestrial counterparts do. Cost, spectral lines near 1 GHz, and interstellar scintillation favor radiating frequencies substantially above the classic "water hole." Therefore, the transmission strategy for a distant, cost-conscious beacon would be a rapid scan of the galactic plane with the intent to cover the angular space. Such pulses would be infrequent events for the receiver. Such beacons built by distant, advanced, wealthy societies would have very different characteristics from what SETI researchers seek. Future searches should pay special attention to areas along the galactic disk where SETI searches have seen coherent signals that have not recurred on the limited listening time intervals we have used. We will need to wait for recurring events that may arriarrive in intermittent bursts. Several new SETI search strategies have emerged from these ideas. We propose a new test for beacons that is based on the Life Plane hypotheses.

  17. Beach Advisory and Closing Online Notification (BEACON) system

    U.S. Environmental Protection Agency — Beach Advisory and Closing Online Notification system (BEACON) is a colletion of state and local data reported to EPA about beach closings and advisories. BEACON is...

  18. BEACON: automated tool for Bacterial GEnome Annotation ComparisON

    Kalkatawi, Manal M.; Alam, Intikhab; Bajic, Vladimir B.

    2015-01-01

    We developed BEACON, a fast tool for an automated and a systematic comparison of different annotations of single genomes. The extended annotation assigns putative functions to many genes with unknown functions. BEACON is available under GNU General Public License version 3.0 and is accessible at: http://www.cbrc.kaust.edu.sa/BEACON/

  19. 14 CFR 171.269 - Marker beacon performance requirements.

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Marker beacon performance requirements. 171.269 Section 171.269 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Landing System (ISMLS) § 171.269 Marker beacon performance requirements. ISMLS marker beacon equipment...

  20. Doing Forensic on DTUsat-2 Using the Beacon Counter

    Fléron, René

    2016-01-01

    DTUsat-2 was launched into a Polar LEO on a Dnepr rocket out of Yasny on 19th June 2014. After the first few days of beacon recording and precise orbit determination it became apparent that all was not nominal. One notable thing was the relatively low beacon count number. The beacon count reflects...

  1. Solar powered aviation beacon/landing light

    NONE

    2001-07-01

    The objective of the work was to design, develop and test Solar Powered Aviation Landing Lights/Obstruction Beacons. The entire lighting units were to be stand alone devices capable of producing their own individual power supply. The whole process was to be documented to provide insight into the processes and decisions involved. (author)

  2. An analytical model for beaconing in VANETs

    van Eenennaam, Martijn; Remke, Anne Katharina Ingrid; Heijenk, Geert

    2012-01-01

    IEEE 802.11 CSMA/CA is generally considered to be well-understood, and many detailed models are available. However, most models focus on Unicast in small-scale W-LAN scenarios. When modelling beaconing in VANETs, the Broadcast nature and the (potentially) large number of nodes cause phenomena

  3. Quantum radar

    Lanzagorta, Marco

    2011-01-01

    This book offers a concise review of quantum radar theory. Our approach is pedagogical, making emphasis on the physics behind the operation of a hypothetical quantum radar. We concentrate our discussion on the two major models proposed to date: interferometric quantum radar and quantum illumination. In addition, this book offers some new results, including an analytical study of quantum interferometry in the X-band radar region with a variety of atmospheric conditions, a derivation of a quantum radar equation, and a discussion of quantum radar jamming.This book assumes the reader is familiar w

  4. Radar Chart

    National Oceanic and Atmospheric Administration, Department of Commerce — The Radar Chart collection is an archived product of summarized radar data. The geographic coverage is the 48 contiguous states of the United States. These hourly...

  5. 76 FR 17625 - Proposed Information Collection; Comment Request; Emergency Beacon Registrations

    2011-03-30

    ... DEPARTMENT OF COMMERCE National Oceanic and Atmospheric Administration Proposed Information Collection; Comment Request; Emergency Beacon Registrations AGENCY: National Oceanic and Atmospheric... emergency radio beacon. Persons purchasing a digital distress beacon, operating in the frequency range of...

  6. Localization with a mobile beacon in underwater acoustic sensor networks.

    Lee, Sangho; Kim, Kiseon

    2012-01-01

    Localization is one of the most important issues associated with underwater acoustic sensor networks, especially when sensor nodes are randomly deployed. Given that it is difficult to deploy beacon nodes at predetermined locations, localization schemes with a mobile beacon on the sea surface or along the planned path are inherently convenient, accurate, and energy-efficient. In this paper, we propose a new range-free Localization with a Mobile Beacon (LoMoB). The mobile beacon periodically broadcasts a beacon message containing its location. Sensor nodes are individually localized by passively receiving the beacon messages without inter-node communications. For location estimation, a set of potential locations are obtained as candidates for a node's location and then the node's location is determined through the weighted mean of all the potential locations with the weights computed based on residuals.

  7. Localization with a Mobile Beacon in Underwater Acoustic Sensor Networks

    Sangho Lee

    2012-04-01

    Full Text Available Localization is one of the most important issues associated with underwater acoustic sensor networks, especially when sensor nodes are randomly deployed. Given that it is difficult to deploy beacon nodes at predetermined locations, localization schemes with a mobile beacon on the sea surface or along the planned path are inherently convenient, accurate, and energy-efficient. In this paper, we propose a new range-free Localization with a Mobile Beacon (LoMoB. The mobile beacon periodically broadcasts a beacon message containing its location. Sensor nodes are individually localized by passively receiving the beacon messages without inter-node communications. For location estimation, a set of potential locations are obtained as candidates for a node’s location and then the node’s location is determined through the weighted mean of all the potential locations with the weights computed based on residuals.

  8. High-visibility infrared beacons for IFF and combat ID

    Pralle, Martin; Puscasu, Irina; Johnson, Edward; Loges, Peter; Melnyk, James

    2005-05-01

    A new kind of Identification Friend or Foe (IFF) infrared beacon has been demonstrated. The omni-directional beacon consists of a pyramidal array of 1W pulsIR thermal light sources. Operating at a total power of 84W, the beacon can be used to track and identify surface vehicles and personnel with a recognition range of up to 6 miles on the battlefield and in urban environments or the marine boundary layer. Advanced photonic technology enables the beacon to be seen only while using a 3-5 μm or 8-12 μm thermal imaging system. There is no visible or near-IR emission to betray the location of the beacon. The beacon is rugged and will operate from -40 to 50°C ambient temperature, 0-100% relative humidity, 0 - 10,000 ft altitude, and meets MIL-STD 810F and MIL-STD 461E.

  9. Aircraft Position Measurement Using Laser Beacon Optics.

    1981-01-01

    8217Comparison of Solar Concentrators .’ Solar Energy, Vol. 10, p. 93, 1976. 7. Winston , R., ’Light Collection Within the Framework of Goemetrical Optics ...8217 J. Optical Society of Am., Vol. 60, p. 245, 1970. 8. Welford, W. T., tics of Nonimaging Concentrators . New York, Academic Press, T978. 9. Bracewell...helicopter pilot and the flight engineer on board the YO-3A. This thesis will concentrate on the development of the laser beacon, the detector optics

  10. Radar Fundamentals, Presentation

    Jenn, David

    2008-01-01

    Topics include: introduction, radar functions, antennas basics, radar range equation, system parameters, electromagnetic waves, scattering mechanisms, radar cross section and stealth, and sample radar systems.

  11. Development of a universal RNA beacon for exogenous gene detection.

    Guo, Yuanjian; Lu, Zhongju; Cohen, Ira Stephen; Scarlata, Suzanne

    2015-05-01

    Stem cell therapy requires a nontoxic and high-throughput method to achieve a pure cell population to prevent teratomas that can occur if even one cell in the implant has not been transformed. A promising method to detect and separate cells expressing a particular gene is RNA beacon technology. However, developing a successful, specific beacon to a particular transfected gene can take months to develop and in some cases is impossible. Here, we report on an off-the-shelf universal beacon that decreases the time and cost of applying beacon technology to select any living cell population transfected with an exogenous gene. ©AlphaMed Press.

  12. Radar equations for modern radar

    Barton, David K

    2012-01-01

    Based on the classic Radar Range-Performance Analysis from 1980, this practical volume extends that work to ensure applicability of radar equations to the design and analysis of modern radars. This unique book helps you identify what information on the radar and its environment is needed to predict detection range. Moreover, it provides equations and data to improve the accuracy of range calculations. You find detailed information on propagation effects, methods of range calculation in environments that include clutter, jamming and thermal noise, as well as loss factors that reduce radar perfo

  13. Social Radar

    2012-01-01

    RTA HFM-201/RSM PAPER 3 - 1 © 2012 The MITRE Corporation. All Rights Reserved. Social Radar Barry Costa and John Boiney MITRE Corporation...defenders require an integrated set of capabilities that we refer to as a “ social radar.” Such a system would support strategic- to operational-level...situation awareness, alerting, course of action analysis, and measures of effectiveness for each action undertaken. Success of a social radar

  14. 76 FR 2917 - Agency Information Collection Activities: Canadian Border Boat Landing Permit (CBP Form I-68)

    2011-01-18

    ... 235.1(e) and Section 235 of Immigration and Nationality Act. CBP Form I-68 is accessible at http://forms.cbp.gov/pdf/CBP_Form_I68.pdf Current Actions: This submission is being made to extend the...

  15. Planetary Radar

    Neish, Catherine D.; Carter, Lynn M.

    2015-01-01

    This chapter describes the principles of planetary radar, and the primary scientific discoveries that have been made using this technique. The chapter starts by describing the different types of radar systems and how they are used to acquire images and accurate topography of planetary surfaces and probe their subsurface structure. It then explains how these products can be used to understand the properties of the target being investigated. Several examples of discoveries made with planetary radar are then summarized, covering solar system objects from Mercury to Saturn. Finally, opportunities for future discoveries in planetary radar are outlined and discussed.

  16. Beach Advisory and Closing Online Notification (BEACON) system

    Beach Advisory and Closing Online Notification system (BEACON) is a colletion of state and local data reported to EPA about beach closings and advisories. BEACON is the public-facing query of the Program tracking, Beach Advisories, Water quality standards, and Nutrients database (PRAWN) which tracks beach closing and advisory information.

  17. 78 FR 19726 - Agency Information Collection Activities: Visa Waiver Program Carrier Agreement (CBP Form I-775)

    2013-04-02

    ...: 1651-0110. Form Number: CBP Form I-775. Abstract: 8 U.S.C. 1223(a) of the Immigration and Nationality... promulgated at 8 CFR Part 233. A copy of CBP Form I-775 is accessible at: http://forms.cbp.gov/pdf/CBP_Form_I775.pdf . Current Actions: This submission is being made to extend the expiration date with no change...

  18. Recent progress in satellite radio beacon studies with particular emphasis on the ATS-6 radio beacon experiment

    Davies, K.

    1980-01-01

    In May 1974 a new era in satellite radio beacon studies of the ionosphere opened with the ATS-6 Radio Beacon Experiment. The history of radio beacon studies up to that time is reviewed briefly and the particular features of the ATS-6 beacon are discussed together with the basic theory required to interpret the measurements. The main emphasis is on the ATS-6 beacon experiment but other beacon data are discussed which provide the necessary background. The diurnal and seasonal variations of the total electron content and the plasmaspheric content are presented for the U.S.A. and Europe. In winter the plasmaspheric content over the Western Hemisphere maximizes at night while in Europe and the Pacific it appears to peak near noon. This is thought to be caused by flow of plasma from the local and conjugate ionospheres. Night maxima of total electron content are found showing that they do not arise from depletions of the plasmaspheric content. The plasmaspheric content is highly sensitive to solar-terrestrial disturbance, it reaches a minimum on the third day of a storm and may take between 10 and 20 days of partial filling and emptying to recover. Travelling disturbances in U.S.A., Europe, and India show similarities of speeds but not of direction. Beacon observations of micropulsations in total content, tropospheric fluctuations and Fresnel diffraction by intense ionospheric irregularities are discussed together with radio wave scintillations and some applications of beacon radio data to communications and navigation. (orig.)

  19. 76 FR 65216 - Beacon Medical Services, LLC, Aurora, CO; Notice of Negative Determination Regarding Application...

    2011-10-20

    ... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-80,219] Beacon Medical Services... workers and former workers of Beacon Medical Services, LLC, Aurora, Colorado (Beacon Medical Services... published in the Federal Register on July 8, 2011 (76 FR 40401). The workers of Beacon Medical Services are...

  20. 78 FR 75392 - American Beacon Funds, et al.; Notice of Application

    2013-12-11

    ... Asset Management LLC; (b) American Beacon Balanced Fund--the Manager, Barrow, Hanley, Mewhinney... Beacon Funds, et al.; Notice of Application December 5, 2013. AGENCY: Securities and Exchange Commission...) (order). Applicants: American Beacon Funds and American Beacon Select Funds (collectively, the ``Trusts...

  1. Diagnosis of Neisseria gonorrhoeae Using Molecular Beacon

    Patel, Achchhe Lal; Sonkar, Subash Chandra; Kumari, Indu; Saluja, Daman

    2015-01-01

    Neisseria gonorrhoeae is an important sexually transmitted diseases (STD) causing pathogen worldwide. Due to absence of an affordable diagnostic assay, routine screening of gonococcal infection becomes impossible in developing countries where infection rates are maximum. Treatment is given on the basis of symptoms alone which leads to spread of infection. Thus, development of a rapid, sensitive, specific, and PCR based visual diagnostic assay suitable for developing countries, required for better disease management, is aimed at in present study. Endocervical swabs were collected from patients visiting gynecology department of various hospitals in Delhi. In-house PCR based assay was developed and modified to visual assay using molecular beacon for end-point detection. It was evaluated against Roche AMPLICOR NG kit and rmp gene. Specificity of beacon was confirmed by competition experiments. Diagnostic test was 98.21% specific and 99.59% sensitive whereas negative and positive predicted value were 99.40% and 98.78%, respectively. We also observed that twice the concentration (2X) of premix was stable at 4°C for 4 months and dry swab samples gave concordant results with that of wet swabs. These features make the test best suitable for routine diagnosis of genital infections in developing countries. PMID:25802857

  2. Molecular Beacon-Based MicroRNA Imaging During Neurogenesis.

    Lee, Jonghwan; Kim, Soonhag

    2016-01-01

    The fluorescence monitoring system for examining endogenous microRNA (miRNA) activity in cellular level provides crucial information on not only understanding a critical role of miRNA involving a variety of biological processes, but also evaluating miRNA expression patterns in a noninvasive manner. In this protocol, we report the details of a new procedure for a molecular beacon-based miRNA monitoring system, which includes the illustration scheme for miRNA detection strategy, exogenous miRNA detection, and measurement of endogenous miRNA expression level during neurogenesis. The fluorescence signal of miR-124a beacon quenched by BHQ2 was gradually recovered as increasing concentration of the miR-124a in tube. The functional work of miR-124a beacon was examined in intracellular environment, allowing for the internalization of the miR-124a beacon by lipofectamine, which resulted in activated fluorescent signals of the miR-124a beacon in the HeLa cells after the addition of synthetic miR-124a. The endogenous miR-124a expression level was detected by miR-124a beacon system during neurogenesis, showing brighter fluorescence intensity in cytoplasmic area of P19 cells after induction of neuronal differentiation by retinoic acid. The molecular beacon based-miRNA detection technique could be applicable to the simultaneous visualization of a variety of miRNA expression patterns using different fluorescence dyes. For the study of examining endogenous miRNA expression level using miRNA-beacon system, if cellular differentiation step is already prepared, transfection step of miR-124a beacon into P19 cells, and acquisition of activated fluorescence signal measured by confocal microscope can be conducted approximately within 6 h.

  3. Do rufous hummingbirds (Selasphorus rufus) use visual beacons?

    Hurly, T Andrew; Franz, Simone; Healy, Susan D

    2010-03-01

    Animals are often assumed to use highly conspicuous features of a goal to head directly to that goal ('beaconing'). In the field it is generally assumed that flowers serve as beacons to guide pollinators. Artificial hummingbird feeders are coloured red to serve a similar function. However, anecdotal reports suggest that hummingbirds return to feeder locations in the absence of the feeder (and thus the beacon). Here we test these reports for the first time in the field, using the natural territories of hummingbirds and manipulating flowers on a scale that is ecologically relevant to the birds. We compared the predictions from two distinct hypotheses as to how hummingbirds might use the visual features of rewards: the distant beacon hypothesis and the local cue hypothesis. In two field experiments, we found no evidence that rufous hummingbirds used a distant visual beacon to guide them to a rewarded location. In no case did birds abandon their approach to the goal location from a distance; rather they demonstrated remarkable accuracy of navigation by approaching to within about 70 cm of a rewarded flower's original location. Proximity varied depending on the size of the training flower: birds flew closer to a previously rewarded location if it had been previously signalled with a small beacon. Additionally, when provided with a beacon at a new location, birds did not fly directly to the new beacon. Taken together, we believe these data demonstrate that these hummingbirds depend little on visual characteristics to beacon to rewarded locations, but rather that they encode surrounding landmarks in order to reach the goal and then use the visual features of the goal as confirmation that they have arrived at the correct location.

  4. Snapshot analysis for rhodium fixed incore detector using BEACON methodology

    Cha, Kyoon Ho; Choi, Yu Sun; Lee, Eun Ki; Park, Moon Ghu; Morita, Toshio; Heibel, Michael D.

    2004-01-01

    The purpose of this report is to process the rhodium detector data of the Yonggwang nuclear unit 4 cycle 5 core for the measured power distribution by using the BEACON methodology. Rhodium snapshots of the YGN 4 cycle 5 have been analyzed by both BEACON/SPINOVA and CECOR to compare the results of both codes. By analyzing a large number of snapshots obtained during normal plant operation. Reviewing the results of this analysis, the BEACON/SPNOVA can be used for the snapshot analysis of Korean Standard Nuclear Power (KSNP) plants

  5. BEACON TSM application system to the operation of PWR reactors

    Lozano, J. A.; Mildrum, C.; Serrano, J. F.

    2012-01-01

    BEACON-TSM is an advanced core monitoring system for PWR reactor cores, and also offers the possibility to perform a wide range of predictive calculation in support of reactor operation. BEACON-TSM is presently installed and licensed in the 5 Spanish PWR reactors of standard Westinghouse design. the purpose of this paper is to describe the features of this software system and to show the advantages obtainable by a nuclear power plant from its use. To illustrate the capabilities and benefits of BEACON-TSM two real case reactor operating situations are presented. (Author)

  6. Beacon-S TM: Non-uniform attenuation correction for SPECT imaging. The new medium-energy transmission device for AXIS and IRIX

    Daniel Gagnon, D.

    1999-01-01

    The paper presents new medium-energy transmission device for SPECT imaging. Beacon-S includes a 356-keV medium energy 133 Ba source with a 10.54-year half-life. Beacon-S provide high-resolution and high-contrast transmission scans. The higher energy of the gamma substantially improves the transmission contrast for larger patients by virtue of better penetration through the body

  7. Early Detection of Breast Cancer Using Molecular Beacons

    Yang, Lily

    2008-01-01

    .... We proposed to use molecular beacon technology to detect the level of expression of several biomarker genes that are highly expressed in breast cancer cells but not in normal breast epithelial cells...

  8. Evaluation of light-emitting diode beacon light fixtures.

    2009-12-01

    Rotating beacons containing filament light sources have long been used on highway maintenance trucks : to indicate the presence of the truck to other drivers. Because of advances in light-emitting diode (LED) : technologies, flashing lights containin...

  9. Evaluation of BEACON-COLSS Core Monitoring System Benefits

    Kim, Joon Sung; Park, Young Ho; Morita, Toshio; Book, Michael A.

    2005-01-01

    In Korean Standard Nuclear Power Plant COLSS (Core Operating Limit Supervisory System) is used to monitor the DNBR Power Operating Limit (DNBRPOL) and Linear Heat Rate POL (KWPFPOL). Westinghouse and KNFC have developed an upgraded core monitoring system by combining the BEACON TM core monitoring system 1 (Best Estimate Analyzer for Core Operation . Nuclear) and COLSS into an integrated product that is called BEACON-COLSS. BEACON-COLSS generates the 3-D power distribution corrected by the in-core detectors measurements. The 3-D core power distribution methodology in BEACON-COLSS is significantly better than the synthesis methodology in COLSS. BEACONCOLSS uses the CETOP-D 2 thermal hydraulic code instead of CETOP-1. CETOP-D is a multi-channel thermal hydraulics code that will provide more accurate DNBR calculations than the DNBR calculators currently used in COLSS

  10. Pedestrian hybrid beacon guide : recommendations and case study.

    2014-01-01

    A pedestrian hybrid beacon (PHB) is a traffic control : device similar to a European pedestrian signal : (PELICAN) that was imported to the US and adapted by : engineers in Arizona to increase motorists awareness of : pedestrian crossings at uncon...

  11. A heuristic evaluation of the Facebook's advertising tool beacon

    Jamal, A; Cole, M

    2009-01-01

    Interface usability is critical to the successful adoption of information systems. The aim of this study is to evaluate interface of Facebook's advertising tool Beacon by using privacy heuristics [4]. Beacon represents an interesting case study because of the negative media and user backlash it received. The findings of heuristic evaluation suggest violation of privacy heuristics [4]. Here, analysis identified concerns about user choice and consent, integrity and security of data, and awarene...

  12. Weather Radar Stations

    Department of Homeland Security — These data represent Next-Generation Radar (NEXRAD) and Terminal Doppler Weather Radar (TDWR) weather radar stations within the US. The NEXRAD radar stations are...

  13. Beacon-Colss core monitoring system application and benefits

    Boyd, W.A.; Yoon, T.Y.

    2005-01-01

    Westinghouse and KNFC are creating an upgraded core monitoring system by merging the BEACON system (best estimate analyzer for core operation-nuclear) and COLSS (core operating limit supervisory system) into an integrated product. Although both BEACON and COLSS are core monitoring systems that have been in operation at many plants for a number of years, they each have some features and capabilities that are not in the other. Therefore it has been decided to incorporate portions of COLSS into the beacon system to create an optional level to support core monitoring applications on selected combustion engineering (C-E) designed plants. This optional level in the beacon system will be called BEACON-COLSS and will allow the beacon system to monitor the LCO's and Tech Spec limits at CE plants that currently use COLSS. This paper will present the structure of the new core monitoring system and the benefits it achieves for current COLSS plants, i.e., CE plants in the US and KSNP (Korean standard nuclear power plant). (authors)

  14. 75 FR 42575 - Electronic Signature and Storage of Form I-9, Employment Eligibility Verification

    2010-07-22

    ... Electronic Signature and Storage of Form I-9, Employment Eligibility Verification AGENCY: U.S. Immigration... published an interim final rule to permit electronic signature and storage of the Form I-9. 71 FR 34510... because electronic signature and storage technologies are optional, DHS expects that small entities will...

  15. 78 FR 18457 - Definition of Form I-94 To Include Electronic Format

    2013-03-27

    ... automation of the form I-94 should be delayed, CBP retains discretion to extend implementation for an... automation will not apply to land ports of entry at this time. \\3\\ DHS intends to publish a privacy impact.... CBP anticipates expanding the automation of the Form I-94 to other methods of transportation in the...

  16. 77 FR 43345 - Agency Information Collection Activities: Sponsor's Notice of Change of Address, Form I-865...

    2012-07-24

    ...-0076] Agency Information Collection Activities: Sponsor's Notice of Change of Address, Form I-865...: Sponsor's Notice of Change of Address. (3) Agency form number, if any, and the applicable component of the.... During this 60-day period, USCIS will be evaluating whether to revise the Form I-865. Should USCIS decide...

  17. 78 FR 4858 - Agency Information Collection Activities: Immigrant Petition for Alien Workers, Form I-140...

    2013-01-23

    ...-0015] Agency Information Collection Activities: Immigrant Petition for Alien Workers, Form I-140... Approved Collection. (2) Title of the Form/Collection: Immigrant Petition for Alien Worker. (3) Agency form... other for-profit. The information furnished on Form I-140 will be used by USCIS to classify aliens under...

  18. 77 FR 65706 - Agency Information Collection Activities: Immigrant Petition for Alien Worker, Form I-140...

    2012-10-30

    ...-0015] Agency Information Collection Activities: Immigrant Petition for Alien Worker, Form I-140... Form/Collection: Immigrant Petition for Alien Worker. (3) Agency form number, if any, and the... information furnished on Form I-140 will be used by USCIS to classify aliens under sections 203(b)(1), 203(b...

  19. 75 FR 76021 - Agency Information Collection Activities: Passenger List/Crew List (CBP Form I-418)

    2010-12-07

    ... the Immigration and Nationality Act (INA). This form is filled out upon arrival of any person by water..., and 251.4. A copy of CBP Form I- 418 can be found at http://forms.cbp.gov/pdf/CBP_Form_I418.pdf...

  20. Suppressed Release of Clarithromycin from Tablets by Crystalline Phase Transition of Metastable Polymorph Form I.

    Fujiki, Sadahiro; Watanabe, Narumi; Iwao, Yasunori; Noguchi, Shuji; Mizoguchi, Midori; Iwamura, Takeru; Itai, Shigeru

    2015-08-01

    The pharmaceutical properties of clarithromycin (CAM) tablets containing the metastable form I of crystalline CAM were investigated. Although the dissolution rate of form I was higher than that of stable form II, the release of CAM from form I tablet was delayed. Disintegration test and liquid penetration test showed that the disintegration of the tablet delayed because of the slow penetration of an external solution into form I tablet. Investigation by scanning electron microscopy revealed that the surface of form I tablet was covered with fine needle-shaped crystals following an exposure to the external solution. These crystals were identified as form IV crystals by powder X-ray diffraction. The phenomenon that CAM releases from tablet was inhibited by fine crystals spontaneously formed on the tablet surface could be applied to the design of sustained-release formulation systems with high CAM contents by minimizing the amount of functional excipients. © 2015 Wiley Periodicals, Inc. and the American Pharmacists Association.

  1. Bistatic radar

    Willis, Nick

    2004-01-01

    Annotation his book is a major extension of a chapter on bistatic radar written by the author for the Radar Handbook, 2nd edition, edited by Merrill Skolnik. It provides a history of bistatic systems that points out to potential designers the applications that have worked and the dead-ends not worth pursuing. The text reviews the basic concepts and definitions, and explains the mathematical development of relationships, such as geometry, Ovals of Cassini, dynamic range, isorange and isodoppler contours, target doppler, and clutter doppler spread.Key Features * All development and analysis are

  2. Phase transitions of antibiotic clarithromycin forms I, IV and new form VII crystals.

    Ito, Masataka; Shiba, Rika; Watanabe, Miteki; Iwao, Yasunori; Itai, Shigeru; Noguchi, Shuji

    2018-06-01

    Metastable crystal form I of the antibiotic clarithromycin has a pharmaceutically valuable characteristic that its crystalline phase transition can be applied for its sustained release from tablets. The phase transition of form I was investigated in detail by single crystal and powder X-ray analyses, dynamic vapor sorption analysis and thermal analysis. The single crystal structure of form I revealed that form I was not an anhydrate crystal but contained a partially occupied water molecule in the channel-like void space. Dynamic vapor sorption (DVS) analysis demonstrated that form I crystals reversibly sorbed water molecules in two steps when the relative humidity (RH) increased and finally transited to hydrate form IV at 95% RH. DVS analysis also showed that when the RH decreased form IV crystals lost water molecules at 40% RH and transited to the newly identified anhydrate crystal form VII. Form VII reversibly transited to form IV at lower RH than form I, suggesting that form I is more suitable for manufacturing a sustained-release tablet of CAM utilizing the crystalline phase transition. Copyright © 2018 Elsevier B.V. All rights reserved.

  3. The use of BEACON monitoring in plant power uprates

    Miller, Wade

    2003-01-01

    BEACON is the core support software technology that provides Utilities with continuous 3-D core power distribution monitoring, operational analysis capability, and operations support capability. BEACON monitoring delivers quantifiable plant margins for both reload design and plant operations improvement. When linked to Plant Power Upratings, BEACON permits an improvement in fuel cycle economics through higher peaking factors, higher power levels and higher discharge burnups. Operational flexibility of Uprated Plants is enhanced through elimination of axial power shape and core power tilt specifications. Also, the number of flux maps for these plants is reduced and local power is monitored continuously, permitting faster power escalation. Integrated 3-D power distribution analysis capabilities provide core designers with historical margin data that permits a reduction in core follow requirements as well as reduced curve book data related scope. Examples of specific Uprated Plant applications will be discussed. In anticipation of future needs of Uprated Plants, plans to integrate the technology of BEACON with COLSS are being executed. Finally, the capability to monitor Crud Induced Power Shift (axial offset) is also planned for incorporation into BEACON in the near future and will be discussed

  4. 78 FR 26648 - Agency Information Collection Activities: Passenger List/Crew List (CBP Form I-418)

    2013-05-07

    ..., owners, or agents of vessels in complying with Sections 231 and 251 of the Immigration and Nationality... at http://forms.cbp.gov/pdf/CBP_Form_I418.pdf . Current Actions: This submission is being made to...

  5. 77 FR 2561 - Agency Information Collection Activities: Passenger List/Crew List (CBP Form I-418)

    2012-01-18

    ... use by masters, owners, or agents of vessels in complying with Sections 231 and 251 of the Immigration... I-418 can be found at http://forms.cbp.gov/pdf/CBP_Form_I418.pdf . Current Actions: This submission...

  6. 76 FR 9806 - Agency Information Collection Activities: Passenger List/Crew List (CBP Form I-418)

    2011-02-22

    ..., owners, or agents of vessels in complying with Sections 231 and 251 of the Immigration and Nationality... can be found at http://forms.cbp.gov/pdf/CBP_Form_I418.pdf . Current Actions: This submission is being...

  7. 14 CFR 171.321 - DME and marker beacon performance requirements.

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false DME and marker beacon performance... (MLS) § 171.321 DME and marker beacon performance requirements. (a) The DME equipment must meet the..._regulations/ibr_locations.html. (b) MLS marker beacon equipment must meet the performance requirements...

  8. 77 FR 41271 - Safety Zone; Newburgh to Beacon Swim, Newburgh, Hudson River, NY

    2012-07-13

    ... 1625-AA00 Safety Zone; Newburgh to Beacon Swim, Newburgh, Hudson River, NY AGENCY: Coast Guard, DHS... navigable waters of the Hudson River, NY in the vicinity of Newburgh, NY for the annual Newburgh Beacon Swim... Beacon Swim is an annual recurring event that has a permanent safety zone found at 33 CFR 165.160. The...

  9. Nucleic acid detection using BRET-beacons based on bioluminescent protein-DNA hybrids

    Engelen, W.; van de Wiel, K.M.; Meijer, L.H.H.; Saha, B.; Merkx, M.

    2017-01-01

    Bioluminescent molecular beacons have been developed using a modular design approach that relies on BRET between the bright luciferase NanoLuc and a Cy3 acceptor. While classical molecular beacons are hampered by background fluorescence and scattering, these BRET-beacons allow detection of low pM

  10. Information Dissemination in VANETS by Piggybacking on Beacons -- An Analysis of the Impact of Network Parameters

    Klein Wolterink, W.; Heijenk, Geert; Karagiannis, Georgios

    2011-01-01

    Piggybacking on beacons is a forwarding technique that is regularly used in vehicular ad-hoc network (VANET) research as a means to disseminate data. With this technique data is attached to and transmitted along with scheduled beacons, without changing the timing of the beacons. In this paper we

  11. Exploring the transformative potential of Bluetooth beacons in higher education

    Kieran McDonald

    2016-11-01

    Full Text Available The growing ubiquity of smartphones and tablet devices integrated into personal, social and professional life, facilitated by expansive communication networks globally, has the potential to disrupt higher education. Academics and students are considering the future possibilities of exploiting these tools and utilising networks to consolidate and expand knowledge, enhancing learning gain. Bluetooth beacon technology has been developed by both Apple and Google as a way to situate digital information within physical spaces, and this paper reflects on a beacon intervention in a contemporary art school in higher education conducted by the authors intended to develop a situated community of practice in Art & Design. The paper describes the project, including relevant theoretical foundations and background to the beacon technology, with regards to the potential of using these devices to create a connected learning community by enhancing learning and facilitating knowledge creation in a borderless learning space.

  12. Detection of thermocouple malfunction in the Beacon system

    Morita, T.; Heibel, M.D.; Congedo, T.V.

    1992-01-01

    The BEACON system uses Core Exit Thermocouples (T/C) extensively for continuous radial power distribution monitoring. The T/C's are used to adjust the reference power distribution generated by the BEACON system to match the current radial power distribution. T/C reliability, repeatability, and relative accuracy have been very satisfactory. However, it is very important to detect any T/C malfunctions during operation, since a T/C signal change caused by an undetected malfunction can lead to serious errors in the radial power distribution developed by BEACON. A simple procedure has been developed which is capable of discriminating between changes in T/C signals caused by actual changes in reactor conditions and signal changes caused by T/C malfunctions

  13. Comparison of BEACON and COMPARE reactor cavity subcompartment analyses

    Burkett, M.W.; Idar, E.S.; Gido, R.G.; Lime, J.F.; Koestel, A.

    1984-04-01

    In this study, a more advanced best-estimate containment code, BEACON-MOD3A, was ued to calculate force and moment loads resulting from a high-energy blowdown for two reactor cavity geometries previously analyzed with the licensing computer code COMPARE-MOD1A. The BEACON force and moment loads were compared with the COMPARE results to determine the safety margins provided by the COMPARE code. The forces and moments calculated by the codes were found to be different, although not in any consistent manner, for the two reactor cavity geometries studied. Therefore, generic summary statements regarding margins cannot be made because of the effects of the detailed physical configuration. However, differences in the BEACON and COMPARE calculated forces and moments can be attributed to differences in the modeling assumptions used in the codes and the analyses

  14. Some early results from the ATS-6 radio beacon experiment

    Davies, K.; Fritz, R.B.; Grubb, R.N.; Jones, J.E.

    1975-01-01

    The multifrequency satellite radio beacon enables the measurement of the columnar electron content of the ionosphere and plasmasphere along the ray path and its spatial and temporal structure. Measurements include modulation phase, Faraday rotation, and amplitude. The characteristics of the beacon transmitter and its design are presented together with the design of the Boulder receiver and antennas and the calibration procedures. A shape factor F is defined which depends on the electron density and geomagnetic field distributions. It is found that F varies by about 30 percent from day to night. It is shown that the ratio of the plasmaspheric content to total content varies from about 0.08 during the day to about 0.35 at night. Other examples which are presented to illustrate the uses of the radio beacon include sunrise effects, solar flare enhancements of total content, and the ionospheric storms of early July 1974

  15. Studying the influence of stem composition in pH-sensitive molecular beacons onto their sensing properties.

    Dembska, Anna; Kierzek, Elzbieta; Juskowiak, Bernard

    2017-10-16

    Intracellular sensing using fluorescent molecular beacons is a potentially useful strategy for real-time, in vivo monitoring of important cellular events. This work is focused on evaluation of pyrene excimer signaling molecular beacons (MBs) for the monitoring of pH changes in vitro as well as inside living cells. The recognition element in our MB called pHSO (pH-sensitive oligonucleotide) is the loop enclosing cytosine-rich fragment that is able to form i-motif structure in a specific pH range. However, alteration of a sequence of the 6 base pairs containing stem of MB allowed the design of pHSO probes that exhibited different dynamic pH range and possessed slightly different transition midpoint between i-motif and open loop configuration. Moreover, this conformational transition was accompanied by spectral changes showing developed probes different pyrene excimer-monomer emission ratio triggered by pH changes. The potential of these MBs for intracellular pH sensing is demonstrated on the example of HeLa cells line. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. BEACON: automated tool for Bacterial GEnome Annotation ComparisON.

    Kalkatawi, Manal; Alam, Intikhab; Bajic, Vladimir B

    2015-08-18

    Genome annotation is one way of summarizing the existing knowledge about genomic characteristics of an organism. There has been an increased interest during the last several decades in computer-based structural and functional genome annotation. Many methods for this purpose have been developed for eukaryotes and prokaryotes. Our study focuses on comparison of functional annotations of prokaryotic genomes. To the best of our knowledge there is no fully automated system for detailed comparison of functional genome annotations generated by different annotation methods (AMs). The presence of many AMs and development of new ones introduce needs to: a/ compare different annotations for a single genome, and b/ generate annotation by combining individual ones. To address these issues we developed an Automated Tool for Bacterial GEnome Annotation ComparisON (BEACON) that benefits both AM developers and annotation analysers. BEACON provides detailed comparison of gene function annotations of prokaryotic genomes obtained by different AMs and generates extended annotations through combination of individual ones. For the illustration of BEACON's utility, we provide a comparison analysis of multiple different annotations generated for four genomes and show on these examples that the extended annotation can increase the number of genes annotated by putative functions up to 27%, while the number of genes without any function assignment is reduced. We developed BEACON, a fast tool for an automated and a systematic comparison of different annotations of single genomes. The extended annotation assigns putative functions to many genes with unknown functions. BEACON is available under GNU General Public License version 3.0 and is accessible at: http://www.cbrc.kaust.edu.sa/BEACON/ .

  17. Beacon communities' public health initiatives: a case study analysis.

    Massoudi, Barbara L; Marcial, Laura H; Haque, Saira; Bailey, Robert; Chester, Kelley; Cunningham, Shellery; Riley, Amanda; Soper, Paula

    2014-01-01

    The Beacon Communities for Public Health (BCPH) project was launched in 2011 to gain a better understanding of the range of activities currently being conducted in population- and public health by the Beacon Communities. The project highlighted the successes and challenges of these efforts with the aim of sharing this information broadly among the public health community. The Beacon Community Program, designed to showcase technology-enabled, community-based initiatives to improve outcomes, focused on: building and strengthening health information technology (IT) infrastructure and exchange capabilities; translating investments in health IT to measureable improvements in cost, quality, and population health; and, developing innovative approaches to performance measurement, technology, and care delivery. Four multimethod case studies were conducted based on a modified sociotechnical framework to learn more about public health initiative implementation and use in the Beacon Communities. Our methodological approach included using document review and semistructured key informant interviews. NACCHO Model Practice Program criteria were used to select the public health initiatives included in the case studies. Despite differences among the case studies, common barriers and facilitators were found to be present in all areas of the sociotechnical framework application including structure, people, technology, tasks, overarching considerations, and sustainability. Overall, there were many more facilitators (range = 7-14) present for each Beacon compared to barriers (range = 4-6). Four influential promising practices were identified through the work: forging strong and sustainable partnerships; ensuring a good task-technology fit and a flexible and iterative design; fostering technology acceptance; and, providing education and demonstrating value. A common weakness was the lack of a framework or model for the Beacon Communities evaluation work. Sharing a framework or approach

  18. Beacon Communities’ Public Health Initiatives: A Case Study Analysis

    Massoudi, Barbara L.; Marcial, Laura H.; Haque, Saira; Bailey, Robert; Chester, Kelley; Cunningham, Shellery; Riley, Amanda; Soper, Paula

    2014-01-01

    Introduction: The Beacon Communities for Public Health (BCPH) project was launched in 2011 to gain a better understanding of the range of activities currently being conducted in population- and public health by the Beacon Communities. The project highlighted the successes and challenges of these efforts with the aim of sharing this information broadly among the public health community. Background: The Beacon Community Program, designed to showcase technology-enabled, community-based initiatives to improve outcomes, focused on: building and strengthening health information technology (IT) infrastructure and exchange capabilities; translating investments in health IT to measureable improvements in cost, quality, and population health; and, developing innovative approaches to performance measurement, technology, and care delivery. Methods: Four multimethod case studies were conducted based on a modified sociotechnical framework to learn more about public health initiative implementation and use in the Beacon Communities. Our methodological approach included using document review and semistructured key informant interviews. NACCHO Model Practice Program criteria were used to select the public health initiatives included in the case studies. Findings: Despite differences among the case studies, common barriers and facilitators were found to be present in all areas of the sociotechnical framework application including structure, people, technology, tasks, overarching considerations, and sustainability. Overall, there were many more facilitators (range = 7–14) present for each Beacon compared to barriers (range = 4–6). Discussion: Four influential promising practices were identified through the work: forging strong and sustainable partnerships; ensuring a good task-technology fit and a flexible and iterative design; fostering technology acceptance; and, providing education and demonstrating value. Conclusions: A common weakness was the lack of a framework or model for

  19. Frequency Estimator Performance for a Software-Based Beacon Receiver

    Zemba, Michael J.; Morse, Jacquelynne Rose; Nessel, James A.; Miranda, Felix

    2014-01-01

    As propagation terminals have evolved, their design has trended more toward a software-based approach that facilitates convenient adjustment and customization of the receiver algorithms. One potential improvement is the implementation of a frequency estimation algorithm, through which the primary frequency component of the received signal can be estimated with a much greater resolution than with a simple peak search of the FFT spectrum. To select an estimator for usage in a QV-band beacon receiver, analysis of six frequency estimators was conducted to characterize their effectiveness as they relate to beacon receiver design.

  20. Optimalization of Beacon Selection for Localization in Wireless AD-HOC Networks

    Martin Matula

    2008-01-01

    Full Text Available In this paper we engage in optimalization of convenient beacons for localization position of a node in the ad-hoc network. An algorithm designed by us localizes position of moving or static node by RSS (Received Signal Strength method and trilateration. At first, localization of unknown node runs by combination of all beacons. Than optimalizating algorithmreduces the number of beacons (and repeats localization, while only three left. Its reduction is based on highest levels of received signal strength. It is only when signals are from the nearest beacons. Position localizating exactness is statistically interpreted from all localization by beacons combination and its repeating.

  1. RADAR PPI Scope Overlay

    National Oceanic and Atmospheric Administration, Department of Commerce — RADAR PPI Scope Overlays are used to position a RADAR image over a station at the correct resolution. The archive maintains several different RADAR resolution types,...

  2. Advances in bistatic radar

    Willis, Nick

    2007-01-01

    Advances in Bistatic Radar updates and extends bistatic and multistatic radar developments since publication of Willis' Bistatic Radar in 1991. New and recently declassified military applications are documented. Civil applications are detailed including commercial and scientific systems. Leading radar engineers provide expertise to each of these applications. Advances in Bistatic Radar consists of two major sections: Bistatic/Multistatic Radar Systems and Bistatic Clutter and Signal Processing. Starting with a history update, the first section documents the early and now declassified military

  3. Overshadowing of geometric cues by a beacon in a spatial navigation task.

    Redhead, Edward S; Hamilton, Derek A; Parker, Matthew O; Chan, Wai; Allison, Craig

    2013-06-01

    In three experiments, we examined whether overshadowing of geometric cues by a discrete landmark (beacon) is due to the relative saliences of the cues. Using a virtual water maze task, human participants were required to locate a platform marked by a beacon in a distinctively shaped pool. In Experiment 1, the beacon overshadowed geometric cues in a trapezium, but not in an isosceles triangle. The longer escape latencies during acquisition in the trapezium control group with no beacon suggest that the geometric cues in the trapezium were less salient than those in the triangle. In Experiment 2, we evaluated whether generalization decrement, caused by the removal of the beacon at test, could account for overshadowing. An additional beacon was placed in an alternative corner. For the control groups, the beacons were identical; for the overshadow groups, they were visually unique. Overshadowing was again found in the trapezium. In Experiment 3, we tested whether the absence of overshadowing in the triangle was due to the geometric cues being more salient than the beacon. Following training, the beacon was relocated to a different corner. Participants approached the beacon rather than the trained platform corner, suggesting that the beacon was more salient. These results suggest that associative processes do not fully explain cue competition in the spatial domain.

  4. Robot-Beacon Distributed Range-Only SLAM for Resource-Constrained Operation.

    Torres-González, Arturo; Martínez-de Dios, Jose Ramiro; Ollero, Anibal

    2017-04-20

    This work deals with robot-sensor network cooperation where sensor nodes (beacons) are used as landmarks for Range-Only (RO) Simultaneous Localization and Mapping (SLAM). Most existing RO-SLAM techniques consider beacons as passive devices disregarding the sensing, computational and communication capabilities with which they are actually endowed. SLAM is a resource-demanding task. Besides the technological constraints of the robot and beacons, many applications impose further resource consumption limitations. This paper presents a scalable distributed RO-SLAM scheme for resource-constrained operation. It is capable of exploiting robot-beacon cooperation in order to improve SLAM accuracy while meeting a given resource consumption bound expressed as the maximum number of measurements that are integrated in SLAM per iteration. The proposed scheme combines a Sparse Extended Information Filter (SEIF) SLAM method, in which each beacon gathers and integrates robot-beacon and inter-beacon measurements, and a distributed information-driven measurement allocation tool that dynamically selects the measurements that are integrated in SLAM, balancing uncertainty improvement and resource consumption. The scheme adopts a robot-beacon distributed approach in which each beacon participates in the selection, gathering and integration in SLAM of robot-beacon and inter-beacon measurements, resulting in significant estimation accuracies, resource-consumption efficiency and scalability. It has been integrated in an octorotor Unmanned Aerial System (UAS) and evaluated in 3D SLAM outdoor experiments. The experimental results obtained show its performance and robustness and evidence its advantages over existing methods.

  5. The BEACON on-line core monitoring system. Functional upgrades and applications

    Boyd, W.A.; Miller, R.W.

    1997-01-01

    The BEACON TM core monitor system has been in commercial operation since 1989 and was licensed by the USNRC for on-line core power distribution and thermal power limit monitoring in 1994. Since that time BEACON has been installed at 17 plants. Each of these customers has a different perspective on the use of data from BEACON and a different approach on the application of BEACON to support their plant operations. To support these varied needs and approaches the BEACON system has been divided into three operational levels to better match the system functions to the customer needs and approaches to system integration. Based on customer feedback, the BEACON system was upgraded in some areas and streamlined in other areas to better support the needs of each customer. The three operational levels of the BEACON system, the major product upgrades and system evolution that has taken place to support the needs and applications of our customers are discussed. (authors)

  6. Remarks on the observability of single beacon underwater navigation

    Jouffroy, Jerome; Ross, Andrew

    This paper contributes a simple and intuitive result in the analysis of underwater navigation using a single ranging beacon. This analysis should help with the design of small and lightweight underwater vehicles by reducing the amount of instrumentation required for accurate navigation. The concept...

  7. The Westinghouse BEACON on-line core monitoring system

    Buechel, Robert J.; Boyd, William A.; Casadei, Alberto L.

    1995-01-01

    BEACON (Best Estimate Analysis of Core Operations - Nuclear), a core monitoring and operational support package developed by Westinghouse, has been installed at many operating PWRs worldwide. The BEACON system is a real-time monitoring system which can be used in plants with both fixed and movable incore detector systems and utilizes an on-line nodal model combined with core instrumentation data to provide continuous core power distribution monitoring. In addition, accurate core-predictive capabilities utilizing a full core nodal model updated according to plant operating history can be made to provide operational support. Core history information is kept and displayed to help operators anticipate core behavior and take pro-active control actions. The BEACON system has been licensed by the U.S. Nuclear Regulatory Commission for direct, continuous monitoring of DNBR and peak linear heat rate. This allows BEACON to be integrated into the plant technical specifications to permit significant relaxation of operating limitations defined by conventional technical specifications. (author). 4 refs, 2 figs, 1 tab

  8. On the Efficiency of Secure Beaconing in VANETs

    Schoch, Elmar; Kargl, Frank

    Direct inter-vehicle communication enables numerous safety applications like intersection collision warning. Beacons - periodic one-hop link-layer broadcast messages containing, e.g., location, heading, and speed - are the basis for many such applications. For security, current work often requires

  9. Smartphone-Based Indoor Localization with Bluetooth Low Energy Beacons

    Yuan Zhuang

    2016-04-01

    Full Text Available Indoor wireless localization using Bluetooth Low Energy (BLE beacons has attracted considerable attention after the release of the BLE protocol. In this paper, we propose an algorithm that uses the combination of channel-separate polynomial regression model (PRM, channel-separate fingerprinting (FP, outlier detection and extended Kalman filtering (EKF for smartphone-based indoor localization with BLE beacons. The proposed algorithm uses FP and PRM to estimate the target’s location and the distances between the target and BLE beacons respectively. We compare the performance of distance estimation that uses separate PRM for three advertisement channels (i.e., the separate strategy with that use an aggregate PRM generated through the combination of information from all channels (i.e., the aggregate strategy. The performance of FP-based location estimation results of the separate strategy and the aggregate strategy are also compared. It was found that the separate strategy can provide higher accuracy; thus, it is preferred to adopt PRM and FP for each BLE advertisement channel separately. Furthermore, to enhance the robustness of the algorithm, a two-level outlier detection mechanism is designed. Distance and location estimates obtained from PRM and FP are passed to the first outlier detection to generate improved distance estimates for the EKF. After the EKF process, the second outlier detection algorithm based on statistical testing is further performed to remove the outliers. The proposed algorithm was evaluated by various field experiments. Results show that the proposed algorithm achieved the accuracy of <2.56 m at 90% of the time with dense deployment of BLE beacons (1 beacon per 9 m, which performs 35.82% better than <3.99 m from the Propagation Model (PM + EKF algorithm and 15.77% more accurate than <3.04 m from the FP + EKF algorithm. With sparse deployment (1 beacon per 18 m, the proposed algorithm achieves the accuracies of <3.88 m at

  10. BEACON: automated tool for Bacterial GEnome Annotation ComparisON

    Kalkatawi, Manal M.

    2015-08-18

    Background Genome annotation is one way of summarizing the existing knowledge about genomic characteristics of an organism. There has been an increased interest during the last several decades in computer-based structural and functional genome annotation. Many methods for this purpose have been developed for eukaryotes and prokaryotes. Our study focuses on comparison of functional annotations of prokaryotic genomes. To the best of our knowledge there is no fully automated system for detailed comparison of functional genome annotations generated by different annotation methods (AMs). Results The presence of many AMs and development of new ones introduce needs to: a/ compare different annotations for a single genome, and b/ generate annotation by combining individual ones. To address these issues we developed an Automated Tool for Bacterial GEnome Annotation ComparisON (BEACON) that benefits both AM developers and annotation analysers. BEACON provides detailed comparison of gene function annotations of prokaryotic genomes obtained by different AMs and generates extended annotations through combination of individual ones. For the illustration of BEACON’s utility, we provide a comparison analysis of multiple different annotations generated for four genomes and show on these examples that the extended annotation can increase the number of genes annotated by putative functions up to 27 %, while the number of genes without any function assignment is reduced. Conclusions We developed BEACON, a fast tool for an automated and a systematic comparison of different annotations of single genomes. The extended annotation assigns putative functions to many genes with unknown functions. BEACON is available under GNU General Public License version 3.0 and is accessible at: http://www.cbrc.kaust.edu.sa/BEACON/

  11. Smartphone-Based Indoor Localization with Bluetooth Low Energy Beacons.

    Zhuang, Yuan; Yang, Jun; Li, You; Qi, Longning; El-Sheimy, Naser

    2016-04-26

    Indoor wireless localization using Bluetooth Low Energy (BLE) beacons has attracted considerable attention after the release of the BLE protocol. In this paper, we propose an algorithm that uses the combination of channel-separate polynomial regression model (PRM), channel-separate fingerprinting (FP), outlier detection and extended Kalman filtering (EKF) for smartphone-based indoor localization with BLE beacons. The proposed algorithm uses FP and PRM to estimate the target's location and the distances between the target and BLE beacons respectively. We compare the performance of distance estimation that uses separate PRM for three advertisement channels (i.e., the separate strategy) with that use an aggregate PRM generated through the combination of information from all channels (i.e., the aggregate strategy). The performance of FP-based location estimation results of the separate strategy and the aggregate strategy are also compared. It was found that the separate strategy can provide higher accuracy; thus, it is preferred to adopt PRM and FP for each BLE advertisement channel separately. Furthermore, to enhance the robustness of the algorithm, a two-level outlier detection mechanism is designed. Distance and location estimates obtained from PRM and FP are passed to the first outlier detection to generate improved distance estimates for the EKF. After the EKF process, the second outlier detection algorithm based on statistical testing is further performed to remove the outliers. The proposed algorithm was evaluated by various field experiments. Results show that the proposed algorithm achieved the accuracy of EKF algorithm and 15.77% more accurate than EKF algorithm. With sparse deployment (1 beacon per 18 m), the proposed algorithm achieves the accuracies of EKF algorithm and 21.41% better than EKF algorithm. Therefore, the proposed algorithm is especially useful to improve the localization accuracy in environments with sparse beacon deployment.

  12. 8 CFR 211.3 - Expiration of immigrant visas, reentry permits, refugee travel documents, and Form I-551.

    2010-01-01

    ... permits, refugee travel documents, and Form I-551. 211.3 Section 211.3 Aliens and Nationality DEPARTMENT... Expiration of immigrant visas, reentry permits, refugee travel documents, and Form I-551. An immigrant visa, reentry permit, refugee travel document, or Form I-551 shall be regarded as unexpired if the rightful...

  13. 27 CFR 73.32 - May I electronically sign forms I submit electronically to TTB?

    2010-04-01

    ... AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY (CONTINUED) PROCEDURES AND PRACTICES ELECTRONIC SIGNATURES; ELECTRONIC SUBMISSION OF FORMS Electronic Filing of Documents with TTB § 73.32 May I electronically sign forms I submit electronically to TTB? You may electronically sign the electronic form you...

  14. 76 FR 81517 - Agency Information Collection Activities: Form I-131, Revision of an Existing Information...

    2011-12-28

    ... information collection. (2) Title of the Form/Collection: Application for Travel Document. (3) Agency form... DEPARTMENT OF HOMELAND SECURITY U.S. Citizenship and Immigration Services Agency Information...-Day Notice of Information Collection Under Review: Form I- 131, Application for Travel Document. The...

  15. 77 FR 15787 - Agency Information Collection Activities: Form I-131, Revision of an Existing Information...

    2012-03-16

    ... the Form/Collection: Application for Travel Document. (3) Agency Form Number, if any, and the... DEPARTMENT OF HOMELAND SECURITY U.S. Citizenship and Immigration Services Agency Information...-Day Notice of Information Collection Under Review: Form I- 131, Application for Travel Document. The...

  16. 78 FR 40758 - Agency Information Collection Activities: Application for Temporary Protected Status, Form I-821...

    2013-07-08

    ....dhs.gov ; or (3) Mail. Submit written comments to DHS, USCIS, Office of Policy and [[Page 40759... it determines the information may impact the privacy of an individual or is offensive. For additional... obtain supporting documents for Form I-821. The monetary costs incurred to obtain supporting documents...

  17. 77 FR 74687 - Agency Information Collection Activities: Application for Employment Authorization, Form I-765...

    2012-12-17

    ... Policy and Strategy, Chief, Regulatory Coordination Division, 20 Massachusetts Avenue NW., Washington, DC... information provided in comments from public viewing that it determines may impact the privacy of an... required to obtain supporting documents for Forms I-765 and I-765WS. The monetary costs incurred to secure...

  18. 76 FR 12751 - Agency Information Collection Activities: Form I-589, Extension of a Currently Approved...

    2011-03-08

    ... DEPARTMENT OF HOMELAND SECURITY U.S. Citizenship and Immigration Services Agency Information... Witholding of Removal; OMB Control No. 1615-0067. The Department of Homeland Security, U.S. Citizenship and... collection: Form I-589. U.S. Citizenship and Immigration Services (USCIS). (4) Affected public who will be...

  19. 75 FR 54646 - Agency Information Collection Activities: Form I-914; Extension of an Existing Information...

    2010-09-08

    ... DEPARTMENT OF HOMELAND SECURITY U.S. Citizenship and Immigration Services [OMB Control No. 1615.... 1615-0099. The Department of Homeland Security, U.S. Citizenship and Immigration Services (USCIS) will... Homeland Security sponsoring the collection: Form I-914; U.S. Citizenship and Immigration Services (USCIS...

  20. 77 FR 23270 - Agency Information Collection Activities: Form I-290B, Extension of an Existing Information...

    2012-04-18

    ... DEPARTMENT OF HOMELAND SECURITY U.S. Citizenship and Immigration Services Agency Information... Department of Homeland Security, U.S. Citizenship and Immigration Services (USCIS) will be [[Page 23271...: Form I-290B. U.S. Citizenship and Immigration Services. (4) Affected public who will be asked or...

  1. 77 FR 36285 - Agency Information Collection Activities: Form I-693, Revision of a Currently Approved...

    2012-06-18

    ... DEPARTMENT OF HOMELAND SECURITY U.S. Citizenship and Immigration Services Agency Information.... Citizenship and Immigration Services (USCIS) will be submitting the following information collection request... of the Department of Homeland Security sponsoring the collection: Form I-693. U.S. Citizenship and...

  2. 75 FR 39271 - Agency Information Collection Activities: Form I-694, Extension of a Currently Approved...

    2010-07-08

    ... DEPARTMENT OF HOMELAND SECURITY U.S. Citizenship and Immigration Services Agency Information... Department of Homeland Security, U.S. Citizenship and Immigration Services (USCIS) will be submitting the... the Department of Homeland Security sponsoring the collection: Form I-694; U.S. Citizenship and...

  3. 75 FR 47824 - Agency Information Collection Activities: Form I-643, Extension of a Currently Approved...

    2010-08-09

    ... DEPARTMENT OF HOMELAND SECURITY U.S. Citizenship and Immigration Services Agency Information... Security, U.S. Citizenship and Immigration Services (USCIS) will be submitting the following information... collection: Form I-643; U.S. Citizenship and Immigration Services (USCIS). (4) Affected public who will be...

  4. 76 FR 55081 - Agency Information Collection Activities: Form I-129S; Extension of an Existing Information...

    2011-09-06

    ... DEPARTMENT OF HOMELAND SECURITY U.S. Citizenship and Immigration Services Agency Information... Blanket L Petition. The Department Homeland Security, U.S. Citizenship and Immigration Services (USCIS... of the Department of Homeland Security sponsoring the collection: Form I-129S; U.S. Citizenship and...

  5. 77 FR 31033 - Agency Information Collection Activities: Form I-589, Extension of a Currently Approved...

    2012-05-24

    ... DEPARTMENT OF HOMELAND SECURITY U.S. Citizenship and Immigration Services Agency Information... Withholding of Removal. The Department of Homeland Security, U.S. Citizenship and Immigration Services (USCIS... collection: Form I-589. U.S. Citizenship and Immigration Services (USCIS). (4) Affected public who will be...

  6. 77 FR 34053 - Agency Information Collection Activities: Form I-590, Extension of a Currently Approved...

    2012-06-08

    ... DEPARTMENT OF HOMELAND SECURITY U.S. Citizenship and Immigration Services Agency Information... Classification as Refugee. The Department of Homeland Security, U.S. Citizenship and Immigration Services (USCIS... Security sponsoring the collection: Form I-590; U.S. Citizenship and Immigration Services (USCIS). (4...

  7. 77 FR 50710 - Agency Information Collection Activities: Employment Eligibility Verification, Form I-9, OMB...

    2012-08-22

    ... DEPARTMENT OF HOMELAND SECURITY U.S. Citizenship and Immigration Services Agency Information...), U.S. Citizenship and Immigration Services (USCIS) will be submitting the following information... sponsoring the collection: Form I-9. U.S. Citizenship and Immigration Services. (4) Affected public who will...

  8. 75 FR 6212 - Agency Information Collection Activities: Form I-129, Revision of an Existing Information...

    2010-02-08

    ... DEPARTMENT OF HOMELAND SECURITY U.S. Citizenship and Immigration Services Agency Information... Control Number 1615-0009. The Department of Homeland Security, U.S. Citizenship and Immigration Services... the Department of Homeland Security sponsoring the collection: Form I-129. U.S. Citizenship and...

  9. 77 FR 27473 - Agency Information Collection Activities: Form I-924; Extension of an Existing Information...

    2012-05-10

    ... Immigrant Investor Pilot Program. The Department of Homeland Security (DHS), U.S. Citizenship and... is published to obtain comments from the public and affected agencies. Comments are encouraged and... whether to revise the Application for Regional Center Under the Immigrant Investor Pilot Program, Form I...

  10. 77 FR 71432 - Agency Information Collection Activities: Immigrant Petition by Alien Entrepreneur, Form I-526...

    2012-11-30

    ...-0026] Agency Information Collection Activities: Immigrant Petition by Alien Entrepreneur, Form I-526.../Collection: Immigrant Petition by Alien Entrepreneur. (3) Agency form number, if any, and the applicable... abstract: Primary: Individuals or Households. This form is used by the USCIS to determine if an alien can...

  11. 76 FR 10609 - Agency Information Collection Activities: Form I-290B, Revision of an Existing Information...

    2011-02-25

    ...: 30-Day Notice of Information Collection Under Review: Form I- 290B, Notice of Appeal to the Office of Administrative Appeals (AAO); OMB Control No. 1615-0095. The Department of Homeland Security, U.S. Citizenship... submission of responses. Overview of this information collection: (1) Type of Information Collection...

  12. 77 FR 6134 - Agency Information Collection Activities: Form I-290B, Extension of an Existing Information...

    2012-02-07

    ...: 60-Day Notice of Information Collection Under Review: Form I- 290B, Notice of Appeal or Motion...., permitting electronic submission of responses. Overview of this information collection: (1) Type of...: Notice of Appeal or Motion. (3) Agency form number, if any, and the applicable component of the...

  13. 76 FR 12750 - Agency Information Collection Activities: Form I-829, Extension of an Existing Information...

    2011-03-08

    ... ACTION: 30-Day Notice of Information Collection Under Review: Form I- 829, Petition by Entrepreneur to... the Form/Collection: Petition by Entrepreneur to Remove Conditions. (3) Agency form number, if any... conditional resident alien entrepreneur who obtained such status through a qualifying investment, to apply to...

  14. 77 FR 14817 - Agency Information Collection Activities: Form I-829, Extension of a Currently Approved...

    2012-03-13

    ...-Day Notice of Information Collection Under Review: Form I- 829, Petition by Entrepreneur to Remove... existing information collection. (2) Title of the Form/Collection: Petition by Entrepreneur to Remove... households. This form is used by a conditional resident alien entrepreneur who obtained such status through a...

  15. 77 FR 33758 - Agency Information Collection Activities: Form I-829, Extension of a Currently Approved...

    2012-06-07

    ... ACTION: 60-Day Notice of Information Collection Under Review: Form I- 829, Petition by Entrepreneur to...: Extension of an existing information collection. (2) Title of the Form/Collection: Petition by Entrepreneur...: Individuals and households. This form is used by a conditional resident alien entrepreneur who obtained such...

  16. 75 FR 74070 - Agency Information Collection Activities: Form I-829, Extension of a Currently Approved...

    2010-11-30

    ... ACTION: 60-Day notice of information collection under review: Form I- 829, Petition by Entrepreneur to... existing information collection. (2) Title of the Form/Collection: Petition by Entrepreneur to Remove... households. This form is used by a conditional resident alien entrepreneur who obtained such status through a...

  17. Radar and Lidar Radar DEM

    Liskovich, Diana; Simard, Marc

    2011-01-01

    Using radar and lidar data, the aim is to improve 3D rendering of terrain, including digital elevation models (DEM) and estimates of vegetation height and biomass in a variety of forest types and terrains. The 3D mapping of vegetation structure and the analysis are useful to determine the role of forest in climate change (carbon cycle), in providing habitat and as a provider of socio-economic services. This in turn will lead to potential for development of more effective land-use management. The first part of the project was to characterize the Shuttle Radar Topography Mission DEM error with respect to ICESat/GLAS point estimates of elevation. We investigated potential trends with latitude, canopy height, signal to noise ratio (SNR), number of LiDAR waveform peaks, and maximum peak width. Scatter plots were produced for each variable and were fitted with 1st and 2nd degree polynomials. Higher order trends were visually inspected through filtering with a mean and median filter. We also assessed trends in the DEM error variance. Finally, a map showing how DEM error was geographically distributed globally was created.

  18. Minimum redundancy MIMO radars

    Chen, Chun-Yang; Vaidyanathan, P. P.

    2008-01-01

    The multiple-input multiple-output (MIMO) radar concept has drawn considerable attention recently. In the traditional single-input multiple-output (SIMO) radar system, the transmitter emits scaled versions of a single waveform. However, in the MIMO radar system, the transmitter transmits independent waveforms. It has been shown that the MIMO radar can be used to improve system performance. Most of the MIMO radar research so far has focused on the uniform array. However, i...

  19. Beacon-based tourist information system to identify visiting trends of tourists

    Akihiro Yamaguchi

    2017-11-01

    Full Text Available In this study, we propose a system that provides tourist information and obtains trends of visiting tourists using beacons and cloud service. As part of our research, we are working on the promotion of local area tourism in cooperation with a local community. A low energy Bluetooth device is used as a beacon to transmit a universally unique identifier. In addition, beacons are placed at sightseeing spots and tourist facilities. Our proposed system comprises two application programs; one is a client-side application program that provides area-specific tourist information corresponding to the detected beacon. The other is a server-side application to record time and location information of the detected beacons. In this paper, we describe the scheme of our system, and present the results of experiments conducted using the prototype system in the local tourist area. In addition, we discuss an open platform for information collection services using beacons.

  20. Solid-state NMR studies of form I of atorvastatin calcium.

    Wang, Wei David; Gao, Xudong; Strohmeier, Mark; Wang, Wei; Bai, Shi; Dybowski, Cecil

    2012-03-22

    Solid-state (13)C, (19)F, and (15)N magic angle spinning NMR studies of Form I of atorvastatin calcium are reported, including chemical shift tensors of all resolvable carbon sites and fluorine sites. The complete (13)C and (19)F chemical shift assignments are given based on an extensive analysis of (13)C-(1)H HETCOR and (13)C-(19)F HETCOR results. The solid-state NMR data indicate that the asymmetric unit of this material contains two atorvastatin molecules. A possible structure of Form I of atorvastatin calcium (ATC-I), derived from solid-state NMR data and density functional theory calculations of various structures, is proposed for this important active pharmaceutical ingredient (API).

  1. SU-E-J-257: Image Artifacts Caused by Implanted Calypso Beacons in MRI Studies

    Amro, H; Chetty, I; Gordon, J; Wen, N

    2014-01-01

    Purpose: The presence of Calypso Beacon-transponders in patients can cause artifacts during MRI imaging studies. This could be a problem for post-treatment follow up of cancer patients using MRI studies to evaluate metastasis and for functional imaging studies.This work assesses (1) the volume immediately surrounding the transponders that will not be visualized by the MRI due to the beacons, and (2) the dependence of the non-visualized volume on beacon orientation, and scanning techniques. Methods: Two phantoms were used in this study (1) water filled box, (2) and a 2300 cc block of pork meat. Calypso beacons were implanted in the phantoms both in parallel and perpendicular orientations with respect to the MR scanner magnetic field. MR image series of the phantom were obtained with on a 1.0T high field open MR-SIM with multiple pulse sequences, for example, T1-weighted fast field echo and T2-weighted turbo spin echo. Results: On average, a no-signal region with 2 cm radius and 3 cm length was measured. Image artifacts are more significant when beacons are placed parallel to scanner magnetic field; the no-signal area around the beacon was about 0.5 cm larger in orthogonal orientation. The no-signal region surrounding the beacons slightly varies in dimension for the different pulse sequences. Conclusion: The use of Calypso beacons can prohibit the use of MRI studies in post-treatment assessments, especially in the immediate region surrounding the implanted beacon. A characterization of the MR scanner by identifying the no-signal regions due to implanted beacons is essential. This may render the use of Calypso beacons useful for some cases and give the treating physician a chance to identify those patients prior to beacon implantation

  2. Q-Band (37-41 GHz) Satellite Beacon Architecture for RF Propagation Experiments

    Simmons, Rainee N.; Wintucky, Edwin G.

    2012-01-01

    In this paper, the design of a beacon transmitter that will be flown as a hosted payload on a geostationary satellite to enable propagation experiments at Q-band (37-41 GHz) frequencies is presented. The beacon uses a phased locked loop stabilized dielectric resonator oscillator and a solid-state power amplifier to achieve the desired output power. The satellite beacon antenna is configured as an offset-fed cut-paraboloidal reflector.

  3. Q-Band (37 to 41 GHz) Satellite Beacon Architecture for RF Propagation Experiments

    Simons, Rainee N.; Wintucky, Edwin G.

    2014-01-01

    In this paper, the design of a beacon transmitter that will be flown as a hosted payload on a geostationary satellite to enable propagation experiments at Q-band (37 to 41 GHz) frequencies is presented. The beacon uses a phased locked loop stabilized dielectric resonator oscillator and a solid-state power amplifier to achieve the desired output power. The satellite beacon antenna is configured as an offset-fed cutparaboloidal reflector.

  4. An Analysis of the Optimal Placement of Beacon in Bluetooth-INS Indoor Localization

    Zhao, Xinyu; Ruan, Ling; Zhang, Ling; Long, Yi; Cheng, Fei

    2018-01-01

    The placement of Bluetooth beacon has immediate impact on the accuracy and stability of indoor positioning. Affected by the shelter of building and human, Bluetooth shows uncertain spatial transmission characteristics. Therefore, the scientific deployment of the beacon nodes is closely related to the indoor space environment. In the study of positioning technology using Bluetooth, some scholars have discussed the deployment of Bluetooth beacon in different scenarios. In the principle of avoid...

  5. SU-E-J-257: Image Artifacts Caused by Implanted Calypso Beacons in MRI Studies

    Amro, H; Chetty, I; Gordon, J; Wen, N [Henry Ford Health System, Detroit, MI (United States)

    2014-06-01

    Purpose: The presence of Calypso Beacon-transponders in patients can cause artifacts during MRI imaging studies. This could be a problem for post-treatment follow up of cancer patients using MRI studies to evaluate metastasis and for functional imaging studies.This work assesses (1) the volume immediately surrounding the transponders that will not be visualized by the MRI due to the beacons, and (2) the dependence of the non-visualized volume on beacon orientation, and scanning techniques. Methods: Two phantoms were used in this study (1) water filled box, (2) and a 2300 cc block of pork meat. Calypso beacons were implanted in the phantoms both in parallel and perpendicular orientations with respect to the MR scanner magnetic field. MR image series of the phantom were obtained with on a 1.0T high field open MR-SIM with multiple pulse sequences, for example, T1-weighted fast field echo and T2-weighted turbo spin echo. Results: On average, a no-signal region with 2 cm radius and 3 cm length was measured. Image artifacts are more significant when beacons are placed parallel to scanner magnetic field; the no-signal area around the beacon was about 0.5 cm larger in orthogonal orientation. The no-signal region surrounding the beacons slightly varies in dimension for the different pulse sequences. Conclusion: The use of Calypso beacons can prohibit the use of MRI studies in post-treatment assessments, especially in the immediate region surrounding the implanted beacon. A characterization of the MR scanner by identifying the no-signal regions due to implanted beacons is essential. This may render the use of Calypso beacons useful for some cases and give the treating physician a chance to identify those patients prior to beacon implantation.

  6. Remote sensing of the ionosphere using satellite radio beacons

    Davies, Kenneth

    1991-01-01

    Since the launch of Sputnik I in 1957, satellite radio beacons have been used to measure the total electron content of the ionosphere. A review of the role of satellite beacons in studies of the vertical and spatial structure of the total electron content and on the occurrence of plasma irregularities, both of which affect transionospheric radio signals, is presented. Measurements of Faraday rotation and time of flight give information on the topside of the ionosphere and on the protonosphere. Morphological studies show that the slab thickness of the ionosphere depends on the solar index but is approximately independent of geographical location. Scintillation of amplitude, phase, polarization, and angle provide information on plasma irregularity occurrence in space and time. (author). 23 refs., 16 figs ., 4 tabs

  7. Aftermath of bustamante attack on genomic beacon service.

    Aziz, Md Momin Al; Ghasemi, Reza; Waliullah, Md; Mohammed, Noman

    2017-07-26

    With the enormous need for federated eco-system for holding global genomic and clinical data, Global Alliance for Genomic and Health (GA4GH) has created an international website called beacon service which allows a researcher to find out whether a specific dataset can be utilized to his or her research beforehand. This simple webservice is quite useful as it allows queries like whether a certain position of a target chromosome has a specific nucleotide. However, the increased integration of individuals genomic data into clinical practice and research raised serious privacy concern. Though the answer of such queries are yes or no in Bacon network, it results in serious privacy implication as demonstrated in a recent work from Shringarpure and Bustamante. In their attack model, the authors demonstrated that with a limited number of queries, presence of an individual in any dataset can be determined. We propose two lightweight algorithms (based on randomized response) which captures the efficacy while preserving the privacy of the participants in a genomic beacon service. We also elaborate the strength and weakness of the attack by explaining some of their statistical and mathematical models using real world genomic database. We extend their experimental simulations for different adversarial assumptions and parameters. We experimentally evaluated the solutions on the original attack model with different parameters for better understanding of the privacy and utility tradeoffs provided by these two methods. Also, the statistical analysis further elaborates the different aspects of the prior attack which leads to a better risk management for the participants in a beacon service. The differentially private and lightweight solutions discussed here will make the attack much difficult to succeed while maintaining the fundamental motivation of beacon database network.

  8. Radio beacon synchronization in coherent receivers for nanosatellite applications

    Camps Llorente, Daniel; Piera González, Joan

    2017-01-01

    This document presents a study about the Radio beacon synchronization in coherent receivers for nanosatellite applications. First of all, it is studied the history of these nanosatellites and their actual role in the Aerospace industry, considering their low cost compared to bigger satellites and also because of their availability for all types of companies and people (as universities). These nanosatellites have a wide range of applications, and lots of them depend on the imagination of the u...

  9. Caged molecular beacons: controlling nucleic acid hybridization with light.

    Wang, Chunming; Zhu, Zhi; Song, Yanling; Lin, Hui; Yang, Chaoyong James; Tan, Weihong

    2011-05-28

    We have constructed a novel class of light-activatable caged molecular beacons (cMBs) that are caged by locking two stems with a photo-labile biomolecular interaction or covalent bond. With the cMBs, the nucleic acid hybridization process can be easily controlled with light, which offers the possibility for a high spatiotemporal resolution study of intracellular mRNAs. © The Royal Society of Chemistry 2011

  10. Beta aerosols beacon, a truly portable continuous air monitor

    Prince, R.P.; Garber, F.W.

    1987-01-01

    The Beta Aerosols Beacon (BAB) is a portable (57 lbs) continuous air monitor designed to detect airborne radiation. Utilizing solid state detectors has eliminated the use of lead shielding usually necessary for achieving accurate readings in high background areas, making the monitor lightweight as well as portable. The size of a small suitcase, it can be carried into confined work areas, eliminating the requirement for workers to wear respirators for many maintenance tasks. This paper describes the operation and applications of the BAB

  11. Performance of MAC protocols in beaconing Mobile Adhoc Multibroadcast Networks

    Rico García, Cristina; Lehner, Andreas; Robertson, Patrick; Strang, Thomas

    2010-01-01

    The investigation of infrastructureless safety applications in dierent transportation systems is a hot research topic. The nodes in thevnetwork are designed to advertise to the rest of the nodes informationabout the current traffic situation by means of short beacon messages containing speed, direction, positions and other relevant safety information. The scheduling should be organized by the MAC layer so that the transmitted messages arrive successfully as soon as possible at the recei...

  12. Distributed Beacon Requirements for Branch Point Tolerant Laser Beam Compensation in Extended Atmospheric Turbulence

    Zetterlind, Virgil

    2002-01-01

    .... A least squares reconstructor is implemented for comparison. System performance is presented for various scenarios, including correction time-delays, wave-front sensor noise, and extended beacons...

  13. Rayleigh beacon for measuring the surface profile of a radio telescope.

    Padin, S

    2014-12-01

    Millimeter-wavelength Rayleigh scattering from water droplets in a cloud is proposed as a means of generating a bright beacon for measuring the surface profile of a radio telescope. A λ=3  mm transmitter, with an output power of a few watts, illuminating a stratiform cloud, can generate a beacon with the same flux as Mars in 10 GHz bandwidth, but the beacon has a narrow line width, so it is extremely bright. The key advantage of the beacon is that it can be used at any time, and positioned anywhere in the sky, as long as there are clouds.

  14. a Search for New Physics with the Beacon Mission

    Turyshev, Slava G.; Shao, Michael; Girerd, André; Lane, Benjamin

    The primary objective of the Beyond Einstein Advanced Coherent Optical Network (BEACON) mission is a search for new physics beyond general relativity by measuring the curvature of relativistic space-time around the Earth. This curvature is characterized by the Eddington parameter γ — the most fundamental relativistic gravity parameter and a direct measure for the presence of new physical interactions. BEACON will achieve an accuracy of 1 × 10-9 in measuring the parameter γ, thereby going a factor of 30,000 beyond the present best result involving the Cassini spacecraft. Secondary mission objectives include: (i) a direct measurement of the "frame-dragging" and geodetic precessions in the Earth's rotational gravitomagnetic field, to 0.05% and 0.03% accuracy respectively, (ii) the first measurement of gravity's nonlinear effects on light and the corresponding second order spatial metric's effects to 0.01% accuracy. BEACON will lead to robust advances in tests of fundamental physics — this mission could discover a violation or extension of general relativity and/or reveal the presence of an additional long range interaction in physics. It will provide crucial information to separate modern scalar-tensor theories of gravity from general relativity, probe possible ways for gravity quantization, and test modern theories of cosmological evolution.

  15. Adapting Mobile Beacon-Assisted Localization in Wireless Sensor Networks

    Wei Dong

    2009-04-01

    Full Text Available The ability to automatically locate sensor nodes is essential in many Wireless Sensor Network (WSN applications. To reduce the number of beacons, many mobile-assisted approaches have been proposed. Current mobile-assisted approaches for localization require special hardware or belong to centralized localization algorithms involving some deterministic approaches due to the fact that they explicitly consider the impreciseness of location estimates. In this paper, we first propose a range-free, distributed and probabilistic Mobile Beacon-assisted Localization (MBL approach for static WSNs. Then, we propose another approach based on MBL, called Adapting MBL (A-MBL, to increase the efficiency and accuracy of MBL by adapting the size of sample sets and the parameter of the dynamic model during the estimation process. Evaluation results show that the accuracy of MBL and A-MBL outperform both Mobile and Static sensor network Localization (MSL and Arrival and Departure Overlap (ADO when both of them use only a single mobile beacon for localization in static WSNs.

  16. Adapting mobile beacon-assisted localization in wireless sensor networks.

    Teng, Guodong; Zheng, Kougen; Dong, Wei

    2009-01-01

    The ability to automatically locate sensor nodes is essential in many Wireless Sensor Network (WSN) applications. To reduce the number of beacons, many mobile-assisted approaches have been proposed. Current mobile-assisted approaches for localization require special hardware or belong to centralized localization algorithms involving some deterministic approaches due to the fact that they explicitly consider the impreciseness of location estimates. In this paper, we first propose a range-free, distributed and probabilistic Mobile Beacon-assisted Localization (MBL) approach for static WSNs. Then, we propose another approach based on MBL, called Adapting MBL (A-MBL), to increase the efficiency and accuracy of MBL by adapting the size of sample sets and the parameter of the dynamic model during the estimation process. Evaluation results show that the accuracy of MBL and A-MBL outperform both Mobile and Static sensor network Localization (MSL) and Arrival and Departure Overlap (ADO) when both of them use only a single mobile beacon for localization in static WSNs.

  17. Impact of beacon wavelength on phase-compensation performance

    Enterline, Allison A.; Spencer, Mark F.; Burrell, Derek J.; Brennan, Terry J.

    2017-09-01

    This study evaluates the effects of beacon-wavelength mismatch on phase-compensation performance. In general, beacon-wavelength mismatch occurs at the system level because the beacon-illuminator laser (BIL) and high-energy laser (HEL) are often at different wavelengths. Such is the case, for example, when using an aperture sharing element to isolate the beam-control sensor suite from the blinding nature of the HEL. With that said, this study uses the WavePlex Toolbox in MATLAB® to model ideal spherical wave propagation through various atmospheric-turbulence conditions. To quantify phase-compensation performance, we also model a nominal adaptive-optics (AO) system. We achieve correction from a Shack-Hartmann wavefront sensor and continuous-face-sheet deformable mirror using a least-squares phase reconstruction algorithm in the Fried geometry and a leaky integrator control law. To this end, we plot the power in the bucket metric as a function of BIL-HEL wavelength difference. Our initial results show that positive BIL-HEL wavelength differences achieve better phase compensation performance compared to negative BIL-HEL wavelength differences (i.e., red BILs outperform blue BILs). This outcome is consistent with past results.

  18. Adaptive radar resource management

    Moo, Peter

    2015-01-01

    Radar Resource Management (RRM) is vital for optimizing the performance of modern phased array radars, which are the primary sensor for aircraft, ships, and land platforms. Adaptive Radar Resource Management gives an introduction to radar resource management (RRM), presenting a clear overview of different approaches and techniques, making it very suitable for radar practitioners and researchers in industry and universities. Coverage includes: RRM's role in optimizing the performance of modern phased array radars The advantages of adaptivity in implementing RRMThe role that modelling and

  19. Radar and ARPA manual

    Bole, A G

    2013-01-01

    Radar and ARPA Manual focuses on the theoretical and practical aspects of electronic navigation. The manual first discusses basic radar principles, including principles of range and bearing measurements and picture orientation and presentation. The text then looks at the operational principles of radar systems. Function of units; aerial, receiver, and display principles; transmitter principles; and sitting of units on board ships are discussed. The book also describes target detection, Automatic Radar Plotting Aids (ARPA), and operational controls of radar systems, and then discusses radar plo

  20. Radar Weather Observation

    National Oceanic and Atmospheric Administration, Department of Commerce — Radar Weather Observation is a set of archived historical manuscripts stored on microfiche. The primary source of these radar weather observations manuscript records...

  1. ISTEF Laser Radar Program

    Stryjewski, John

    1998-01-01

    The BMDO Innovative Science and Technology Experimentation Facility (BMDO/ISTEF) laser radar program is engaged in an ongoing program to develop and demonstrate advanced laser radar concepts for Ballistic Missile Defense (BMD...

  2. Weather Radar Impact Zones

    National Oceanic and Atmospheric Administration, Department of Commerce — These data represent an inventory of the national impacts of wind turbine interference with NEXRAD radar stations. This inventory was developed by the NOAA Radar...

  3. Novel radar techniques and applications

    Klemm, Richard; Lombardo, Pierfrancesco; Nickel, Ulrich

    2017-01-01

    Novel Radar Techniques and Applications presents the state-of-the-art in advanced radar, with emphasis on ongoing novel research and development and contributions from an international team of leading radar experts. This volume covers: Real aperture array radar; Imaging radar and Passive and multistatic radar.

  4. Principles of modern radar systems

    Carpentier, Michel H

    1988-01-01

    Introduction to random functions ; signal and noise : the ideal receiver ; performance of radar systems equipped with ideal receivers ; analysis of the operating principles of some types of radar ; behavior of real targets, fluctuation of targets ; angle measurement using radar ; data processing of radar information, radar coverage ; applications to electronic scanning antennas to radar ; introduction to Hilbert spaces.

  5. Translational vibrations between chains of hydrogen-bonded molecules in solid-state aspirin form I

    Takahashi, Masae; Ishikawa, Yoichi

    2013-06-01

    We perform dispersion-corrected first-principles calculations, and far-infrared (terahertz) spectroscopic experiments at 4 K, to examine translational vibrations between chains of hydrogen-bonded molecules in solid-state aspirin form I. The calculated frequencies and relative intensities reproduce the observed spectrum to accuracy of 11 cm-1 or less. The stronger one of the two peaks assigned to the translational mode includes the stretching vibration of the weak hydrogen bond between the acetyl groups of a neighboring one-dimensional chain. The calculation of aspirin form II performed for comparison gives the stretching vibration of the weak hydrogen bond in one-dimensional chain.

  6. Software Radar Technology

    Tang Jun

    2015-08-01

    Full Text Available In this paper, the definition and the key features of Software Radar, which is a new concept, are proposed and discussed. We consider the development of modern radar system technology to be divided into three stages: Digital Radar, Software radar and Intelligent Radar, and the second stage is just commencing now. A Software Radar system should be a combination of various modern digital modular components conformed to certain software and hardware standards. Moreover, a software radar system with an open system architecture supporting to decouple application software and low level hardware would be easy to adopt "user requirements-oriented" developing methodology instead of traditional "specific function-oriented" developing methodology. Compared with traditional Digital Radar, Software Radar system can be easily reconfigured and scaled up or down to adapt to the changes of requirements and technologies. A demonstration Software Radar signal processing system, RadarLab 2.0, which has been developed by Tsinghua University, is introduced in this paper and the suggestions for the future development of Software Radar in China are also given in the conclusion.

  7. Chimeric peptide beacons: a direct polypeptide analog of DNA molecular beacons†

    Oh, Kenneth J.; Cash, Kevin J.; Lubin, Arica A.; Plaxco, Kevin W.

    2007-01-01

    We have developed a new biosensor architecture, which is comprised of a polypeptide–peptide nucleic acid tri-block copolymer and which we have termed chimeric peptide beacons (CPB), that generates an optical output via a mechanism analogous to that employed in DNA-based molecular beacons.

  8. Weak beacon detection for air-to-ground optical wireless link establishment.

    Han, Yaoqiang; Dang, Anhong; Tang, Junxiong; Guo, Hong

    2010-02-01

    In an air-to-ground free-space optical communication system, strong background interference seriously affects the beacon detection, which makes it difficult to establish the optical link. In this paper, we propose a correlation beacon detection scheme under strong background interference conditions. As opposed to traditional beacon detection schemes, the beacon is modulated by an m-sequence at the transmitting terminal with a digital differential matched filter (DDMF) array introduced at the receiving end to detect the modulated beacon. This scheme is capable of suppressing both strong interference and noise by correlation reception of the received image sequence. In addition, the DDMF array enables each pixel of the image sensor to have its own DDMF of the same structure to process its received image sequence in parallel, thus it makes fast beacon detection possible. Theoretical analysis and an outdoor experiment have been demonstrated and show that the proposed scheme can realize fast and effective beacon detection under strong background interference conditions. Consequently, the required beacon transmission power can also be reduced dramatically.

  9. Synthesis and Characterization of a Magnetically Active 19F Molecular Beacon.

    Dempsey, Megan E; Marble, Hetal D; Shen, Tun-Li; Fawzi, Nicolas L; Darling, Eric M

    2018-02-21

    Gene expression is used extensively to describe cellular characteristics and behaviors; however, most methods of assessing gene expression are unsuitable for living samples, requiring destructive processes such as fixation or lysis. Recently, molecular beacons have become a viable tool for live-cell imaging of mRNA molecules in situ. Historically, beacon-mediated imaging has been limited to fluorescence-based approaches. We propose the design and synthesis of a novel molecular beacon for magnetic resonance detection of any desired target nucleotide sequence. The biologically compatible synthesis incorporates commonly used bioconjugation reactions in aqueous conditions and is accessible for laboratories without extensive synthesis capabilities. The resulting beacon uses fluorine ( 19 F) as a reporter, which is broadened, or turned "off", via paramagnetic relaxation enhancement from a stabilized nitroxide radical spin label when the beacon is not bound to its nucleic acid target. Therefore, the 19 F NMR signal of the beacon is quenched in its hairpin conformation when the spin label and the 19 F substituent are held in proximity, but the signal is recovered upon beacon hybridization to its specific complementary nucleotide sequence by physical separation of the radical from the 19 F reporter. This study establishes a path for magnetic resonance-based assessment of specific mRNA expression, providing new possibilities for applying molecular beacon technology in living systems.

  10. Beacon Editor: Capturing Signal Transduction Pathways Using the Systems Biology Graphical Notation Activity Flow Language.

    Elmarakeby, Haitham; Arefiyan, Mostafa; Myers, Elijah; Li, Song; Grene, Ruth; Heath, Lenwood S

    2017-12-01

    The Beacon Editor is a cross-platform desktop application for the creation and modification of signal transduction pathways using the Systems Biology Graphical Notation Activity Flow (SBGN-AF) language. Prompted by biologists' requests for enhancements, the Beacon Editor includes numerous powerful features for the benefit of creation and presentation.

  11. 46 CFR 169.555 - Emergency position indicating radio beacon (EPIRB).

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Emergency position indicating radio beacon (EPIRB). 169.555 Section 169.555 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS... Emergency position indicating radio beacon (EPIRB). (a) Each vessel certificated for exposed waters must...

  12. 46 CFR 169.831 - Emergency position indicating radio beacon (EPIRB).

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Emergency position indicating radio beacon (EPIRB). 169.831 Section 169.831 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS... radio beacon (EPIRB). The master shall ensure that— (a) The EPIRB required in § 169.555 of this...

  13. What Happened to the Beacon Schools? Policy Reform and Educational Equity

    Smith, Emma

    2015-01-01

    This paper considers the impact of the Beacon schools initiative on the social and academic characteristics of secondary schools in England. The Beacon schools programme ran from 1998 to 2004 and epitomised the (then) Labour government's focus on school improvement through diversity, collaboration and partnership. This paper looks at variation in…

  14. 46 CFR 169.744 - Emergency position indicating radio beacon (EPIRB).

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Emergency position indicating radio beacon (EPIRB). 169.744 Section 169.744 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) NAUTICAL SCHOOLS... position indicating radio beacon (EPIRB). Each EPIRB must be marked with the vessel's name. ...

  15. Detecting and Preventing Beacon Replay Attacks in Receiver-Initiated MAC Protocols for Energy Efficient WSNs

    Di Mauro, Alessio; Fafoutis, Xenofon; Mödersheim, Sebastian Alexander

    2013-01-01

    In receiver-initiated MAC protocols for Wireless Sensor Networks (WSNs), communication is initiated by the receiver of the data through beacons containing the receiver's identity. In this paper, we consider the case of a network intruder that captures and replays such beacons towards legitimate...

  16. Beacon- and Schema-Based Method for Recognizing Algorithms from Students' Source Code

    Taherkhani, Ahmad; Malmi, Lauri

    2013-01-01

    In this paper, we present a method for recognizing algorithms from students programming submissions coded in Java. The method is based on the concept of "programming schemas" and "beacons". Schemas are high-level programming knowledge with detailed knowledge abstracted out, and beacons are statements that imply specific…

  17. Crowdsourcing for Context: Regarding Privacy in Beacon Encounters via Contextual Integrity

    Bello-Ogunu Emmanuel

    2016-07-01

    Full Text Available Research shows that context is important to the privacy perceptions associated with technology. With Bluetooth Low Energy beacons, one of the latest technologies for providing proximity and indoor tracking, the current identifiers that characterize a beacon are not sufficient for ordinary users to make informed privacy decisions about the location information that could be shared. One solution would be to have standardized category and privacy labels, produced by beacon providers or an independent third-party. An alternative solution is to find an approach driven by users, for users. In this paper, we propose a novel crowdsourcing based approach to introduce elements of context in beacon encounters.We demonstrate the effectiveness of this approach through a user study, where participants use a crowd-based mobile app designed to collect beacon category and privacy information as a scavenger hunt game. Results show that our approach was effective in helping users label beacons according to the specific context of a given beacon encounter, as well as the privacy perceptions associated with it. This labeling was done with an accuracy of 92%, and with an acceptance rate of 82% of all recommended crowd labels. Lastly, we conclusively show how crowdsourcing for context can be used towards a user-centric framework for privacy management during beacon encounters.

  18. Het effect van beacons in de ByAmfi Store gemeten, geanalyseerd en ontmaskerd

    Moes, Anne; van Vliet, Harry

    2015-01-01

    Volgens meerdere marketeers zijn beacons ‘the next big thing’; en grote retailers als de Bijenkorf zetten beacons al in. Klanten kopen namelijk steeds meer via internet, en winkels zoeken daarom naar manieren om een beleving te bieden, zodat klanten naar de winkel blijven komen.

  19. 78 FR 70570 - Agency Information Collection Activities: Arrival and Departure Record (Forms I-94 and I-94W) and...

    2013-11-26

    ... information technology; and (e) the annual costs burden to respondents or record keepers from the collection... estimated time to complete ESTA or Form I-94W. There are no proposed changes to Form I-94. Type of Review... Responses: 4,387,550. Estimated Time per Response: 8 minutes. Estimated Burden Hours: 583,544. Estimated...

  20. 78 FR 24429 - Agency Information Collection Activities: Inter-Agency Alien Witness and Informant Record, Form I...

    2013-04-25

    ...-0046] Agency Information Collection Activities: Inter-Agency Alien Witness and Informant Record, Form I... the Form/Collection: Inter-Agency Alien Witness and Informant Record. (3) Agency form number, if any... Government. Form I-854 is used by law enforcement agencies to bring alien witnesses and informants to the...

  1. Understanding radar systems

    Kingsley, Simon

    1999-01-01

    What is radar? What systems are currently in use? How do they work? This book provides engineers and scientists with answers to these critical questions, focusing on actual radar systems in use today. It is a perfect resource for those just entering the field, or as a quick refresher for experienced practitioners. The book leads readers through the specialized language and calculations that comprise the complex world of radar engineering as seen in dozens of state-of-the-art radar systems. An easy to read, wide ranging guide to the world of modern radar systems.

  2. Pulse Doppler radar

    Alabaster, Clive

    2012-01-01

    This book is a practitioner's guide to all aspects of pulse Doppler radar. It concentrates on airborne military radar systems since they are the most used, most complex, and most interesting of the pulse Doppler radars; however, ground-based and non-military systems are also included. It covers the fundamental science, signal processing, hardware issues, systems design and case studies of typical systems. It will be a useful resource for engineers of all types (hardware, software and systems), academics, post-graduate students, scientists in radar and radar electronic warfare sectors and milit

  3. Uncertainty analysis for the BEACON-COLSS core monitoring system application

    Morita, T.; Boyd, W.A.; Seong, K.B.

    2005-01-01

    This paper will cover the measurement uncertainty analysis of BEACON-COLSS core monitoring system. The uncertainty evaluation is made by using a BEACON-COLSS simulation program. By simulating the BEACON on-line operation for analytically generated reactor conditions, accuracy of the 'Measured' results can be evaluated by comparing to analytically generated 'Truth'. The DNB power margin is evaluated based on the Combustion Engineering's Modified Statistical Combination of Uncertainties (MSCU) using the CETOPD code for the DNBR calculation. A BEACON-COLSS simulation program for the uncertainty evaluation function has been established for plant applications. Qualification work has been completed for two Combustion Engineering plants. Results of the BEACON-COLSS measured peaking factors and DNBR power margin are plant type dependent and are applicable to reload cores as long as the core geometry and detector layout are unchanged. (authors)

  4. Detection of DNA damage by using hairpin molecular beacon probes and graphene oxide.

    Zhou, Jie; Lu, Qian; Tong, Ying; Wei, Wei; Liu, Songqin

    2012-09-15

    A hairpin molecular beacon tagged with carboxyfluorescein in combination with graphene oxide as a quencher reagent was used to detect the DNA damage by chemical reagents. The fluorescence of molecular beacon was quenched sharply by graphene oxide; while in the presence of its complementary DNA the quenching efficiency decreased because their hybridization prevented the strong adsorbability of molecular beacon on graphene oxide. If the complementary DNA was damaged by a chemical reagent and could not form intact duplex structure with molecular beacon, more molecular beacon would adsorb on graphene oxide increasing the quenching efficiency. Thus, damaged DNA could be detected based on different quenching efficiencies afforded by damaged and intact complementary DNA. The damage effects of chlorpyrifos-methyl and three metabolites of styrene such as mandelieaeids, phenylglyoxylieaeids and epoxystyrene on DNA were studied as models. The method for detection of DNA damage was reliable, rapid and simple compared to the biological methods. Copyright © 2012 Elsevier B.V. All rights reserved.

  5. Addressing Beacon re-identification attacks: quantification and mitigation of privacy risks.

    Raisaro, Jean Louis; Tramèr, Florian; Ji, Zhanglong; Bu, Diyue; Zhao, Yongan; Carey, Knox; Lloyd, David; Sofia, Heidi; Baker, Dixie; Flicek, Paul; Shringarpure, Suyash; Bustamante, Carlos; Wang, Shuang; Jiang, Xiaoqian; Ohno-Machado, Lucila; Tang, Haixu; Wang, XiaoFeng; Hubaux, Jean-Pierre

    2017-07-01

    The Global Alliance for Genomics and Health (GA4GH) created the Beacon Project as a means of testing the willingness of data holders to share genetic data in the simplest technical context-a query for the presence of a specified nucleotide at a given position within a chromosome. Each participating site (or "beacon") is responsible for assuring that genomic data are exposed through the Beacon service only with the permission of the individual to whom the data pertains and in accordance with the GA4GH policy and standards.While recognizing the inference risks associated with large-scale data aggregation, and the fact that some beacons contain sensitive phenotypic associations that increase privacy risk, the GA4GH adjudged the risk of re-identification based on the binary yes/no allele-presence query responses as acceptable. However, recent work demonstrated that, given a beacon with specific characteristics (including relatively small sample size and an adversary who possesses an individual's whole genome sequence), the individual's membership in a beacon can be inferred through repeated queries for variants present in the individual's genome.In this paper, we propose three practical strategies for reducing re-identification risks in beacons. The first two strategies manipulate the beacon such that the presence of rare alleles is obscured; the third strategy budgets the number of accesses per user for each individual genome. Using a beacon containing data from the 1000 Genomes Project, we demonstrate that the proposed strategies can effectively reduce re-identification risk in beacon-like datasets. © The Author 2017. Published by Oxford University Press on behalf of the American Medical Informatics Association.

  6. An Interactive Real-Time Locating System Based on Bluetooth Low-Energy Beacon Network †.

    Lin, You-Wei; Lin, Chi-Yi

    2018-05-21

    The ubiquity of Bluetooth-enabled smartphones and peripherals has brought tremendous convenience to our daily life. In recent years, Bluetooth beacons have also been gaining popularity in implementing a variety of innovative location-based services such as self-guided systems in exhibition centers. However, the broadcast-based beacon technology can only provide unidirectional communication. In case smartphone users would like to respond to the beacon messages, they have to rely on their own mobile Internet connections to send the information back to the backend system. Nevertheless, mobile Internet services may not be always available or too costly. In this work, we develop a real-time locating system based only on the Bluetooth low energy (BLE) technology to support interactive communications by combining the broadcast and mesh topology options to extend the applicability of beacon solutions. Specifically, we turn the smartphone into a beacon device and augment the beacon devices with the capability of forming a mesh network. The implementation result shows that our beacon devices can detect the presence of specific users at specific locations, and then the presence state can be sent to the application server via the relay of beacon devices. Moreover, the application server can send personalized location-based messages to the users, again via the relay of beacon devices. With the capability of relaying messages between the beacon devices, it would be convenient for developers to implement a variety of interactive applications such as tracking VIP customers at the airport, or tracking an elder with Alzheimer’s disease in the neighborhood.

  7. An Interactive Real-Time Locating System Based on Bluetooth Low-Energy Beacon Network †

    You-Wei Lin

    2018-05-01

    Full Text Available The ubiquity of Bluetooth-enabled smartphones and peripherals has brought tremendous convenience to our daily life. In recent years, Bluetooth beacons have also been gaining popularity in implementing a variety of innovative location-based services such as self-guided systems in exhibition centers. However, the broadcast-based beacon technology can only provide unidirectional communication. In case smartphone users would like to respond to the beacon messages, they have to rely on their own mobile Internet connections to send the information back to the backend system. Nevertheless, mobile Internet services may not be always available or too costly. In this work, we develop a real-time locating system based only on the Bluetooth low energy (BLE technology to support interactive communications by combining the broadcast and mesh topology options to extend the applicability of beacon solutions. Specifically, we turn the smartphone into a beacon device and augment the beacon devices with the capability of forming a mesh network. The implementation result shows that our beacon devices can detect the presence of specific users at specific locations, and then the presence state can be sent to the application server via the relay of beacon devices. Moreover, the application server can send personalized location-based messages to the users, again via the relay of beacon devices. With the capability of relaying messages between the beacon devices, it would be convenient for developers to implement a variety of interactive applications such as tracking VIP customers at the airport, or tracking an elder with Alzheimer’s disease in the neighborhood.

  8. Determination of BEACON Coupling Coefficients using data from Xenon transient

    Bozic, M.; Kurincic, B.

    2007-01-01

    NEK uses BEACO TM code (BEACO TM - Westinghouse Best Estimate Analyzer for Core Operating Nuclear) for core monitoring, analysis and core behaviour prediction. Coupling Coefficients determine relationship between core response and excore instrumentation. Measured power distribution using incore moveable detectors during Xenon transient with sufficient power axial offset change is the most important data for further analysis. Classic methodology and BEACO TM Conservative methodology using established Coupling Coefficients are compared on NPP Krsko case. BEACON TM Conservative methodology with predefined Coupling Coefficients is used as a surveillance tool for verification of relationship between core and excore instrumentation during power operation. (author)

  9. Beacon-teknologi - fremtidens kundebehandling eller en trussel for personvernet?

    Jyrkinen, Anna; Kamås, Kamilla

    2016-01-01

    Smarttelefoner har blitt en naturlig del av våre liv. Alt man gjør på smarttelefonen, blir lagret som såkalte “big data”. Dette er verdifull informasjon for bedrifter, da de får mer detaljert bilde av hva forbrukere ser, eller holder på med i det virkelige liv. Det kan oppstå et dilemma ved hvor langt selskapene er villige til å strekke seg, for å samle inn informasjon om sine kunder. Beacons er en ny teknologiform og fungerer via små apparater som kommuniserer med kunder gjenn...

  10. Deep sea AUV navigation using multiple acoustic beacons

    Ji, Da-xiong; Song, Wei; Zhao, Hong-yu; Liu, Jian

    2016-04-01

    Navigation is a critical requirement for the operation of Autonomous Underwater Vehicles (AUVs). To estimate the vehicle position, we present an algorithm using an extended Kalman filter (EKF) to integrate dead-reckoning position with acoustic ranges from multiple beacons pre-deployed in the operating environment. Owing to high latency, variable sound speed multipath transmissions and unreliability in acoustic measurements, outlier recognition techniques are proposed as well. The navigation algorithm has been tested by the recorded data of deep sea AUV during field operations in a variety of environments. Our results show the improved performance over prior techniques based on position computation.

  11. Overview of on-line core monitoring system BEACON

    Dai Qing; Chen Xiaosong

    2013-01-01

    After more than 20 years of development, key technologies embedded with such system have reached a certain degree of maturity among some foreign countries. However, domestically, there is no comparable system yet. Through in-depth research and analysis on the most widely used core monitoring system in the world, BEACON, it's hope that this will provide guidance on our independent development of the first core monitoring system in China. Excore detectors, core outlet thermocouples and incore movable detectors are used to provide measure data on the status of the core for BEACON. Under the assumption of nodal homogeneity, an effective fast group model is used to solve the diffusion equation, followed by core-wise interpolation by Green's function. Finally, reconstruction of a calculated core is fitted with measured data using the surface spline function. The most significant technological advances are core monitoring during unstable core conditions, the use of nodal expansion method to improve accuracy and the adoption of single point calibration to increase the period of recalibration for the whole core. (authors)

  12. Water absorption length measurement with the ANTARES optical beacon system

    Yepes-Ramirez, Harold

    2011-01-01

    ANTARES is a neutrino telescope located in the Mediterranean Sea with the aim of detecting high energy neutrinos of extra-terrestrial origin. It consists of a three dimensional array on 12 detection lines of photomultiplier tubes (PMTs) able to detect the Cherenkov light induced by muons produced in the interaction of neutrinos with the surrounding water and seabed. To reach the best angular resolution, good time and positioning calibrations are required. The propagation of Cherenkov photons strongly depends on the optical properties of the sea water, which has an impact on the reconstruction efficiency. The determination of the optical parameters, as the absorption and scattering lengths, is crucial to calculate properly the effective area and the angular resolution of the detector. The ANTARES optical beacon system consists of pulsed and fast, well controlled light sources distributed throughout the detector to carry out in situ the relative time calibration of the detector components. In this contribution we show some results on the sea water optical properties and their stability measured with the optical beacon system.

  13. Design and implementation of Bluetooth beacon in mobile payment system

    Han, Tiantian; Ding, Lei

    2017-08-01

    The current line of payment means, mainly in the following ways, cash payment, credit card payment, WeChat Alipay sweep payment. There are many inconvenience in Cash payment, large amounts of cash inconvenience to carry, count the money to spend time and effort, true and false banknotes difficult to distinguish, ticket settlement easy to go wrong. Credit card payment is relatively time-consuming, and WeChat Alipay sweep payment need to sweep. Therefore, the design of a convenient, fast payment to meet the line to pay the demand is particularly important. Based on the characteristics of BLE Bluetooth wireless communication technology, this paper designs a kind of payment method based on Bluetooth beacon. Through the Bluetooth beacon broadcast consumption, consumers only need to open the relevant APP in the Android client, and you can get Bluetooth via mobile phone Bluetooth the amount of consumption of the standard broadcast, in accordance with the corresponding payment platform to complete the payment process, which pay less time to improve the efficiency of payment.

  14. Power-Efficient Beacon Recognition Method Based on Periodic Wake-Up for Industrial Wireless Devices.

    Song, Soonyong; Lee, Donghun; Jang, Ingook; Choi, Jinchul; Son, Youngsung

    2018-04-17

    Energy harvester-integrated wireless devices are attractive for generating semi-permanent power from wasted energy in industrial environments. The energy-harvesting wireless devices may have difficulty in their communication with access points due to insufficient power supply for beacon recognition during network initialization. In this manuscript, we propose a novel method of beacon recognition based on wake-up control to reduce instantaneous power consumption in the initialization procedure. The proposed method applies a moving window for the periodic wake-up of the wireless devices. For unsynchronized wireless devices, beacons are always located in the same positions within each beacon interval even though the starting offsets are unknown. Using these characteristics, the moving window checks the existence of the beacon associated withspecified resources in a beacon interval, checks again for neighboring resources at the next beacon interval, and so on. This method can reduce instantaneous power and generates a surplus of charging time. Thus, the proposed method alleviates the problems of power insufficiency in the network initialization. The feasibility of the proposed method is evaluated using computer simulations of power shortage in various energy-harvesting conditions.

  15. DNA aptamer beacon assay for C-telopeptide and handheld fluorometer to monitor bone resorption.

    Bruno, John Gordon; Carrillo, Maria P; Phillips, Taylor; Hanson, Douglas; Bohmann, Jonathan A

    2011-09-01

    A novel DNA aptamer beacon is described for quantification of a 26-amino acid C-telopeptide (CTx) of human type I bone collagen. One aptamer sequence and its reverse complement dominated the aptamer pool (31.6% of sequenced clones). Secondary structures of these aptamers were examined for potential binding pockets. Three-dimensional computer models which analyzed docking topologies and binding energies were in agreement with empirical fluorescence experiments used to select one candidate loop for beacon assay development. All loop structures from the aptamer finalists were end-labeled with TYE 665 and Iowa Black quencher for comparison of beacon fluorescence levels as a function of CTx concentration. The optimal beacon, designated CTx 2R-2h yielded a low ng/ml limit of detection using a commercially available handheld fluorometer. The CTx aptamer beacon bound full-length 26-amino acid CTx peptide, but not a shorter 8-amino acid segment of CTx peptide which is a common target for commercial CTx ELISA kits. The prototype assay was shown to detect CTx peptide from human urine after creatinine and urea were removed by size-exclusion chromatography to prevent nonspecific denaturing of the aptamer beacon. This work demonstrates the potential of aptamer beacons to be utilized for rapid and sensitive bone health monitoring in a handheld or point-of-care format.

  16. Pedestrian and motorists' actions at pedestrian hybrid beacon sites: findings from a pilot study.

    Pulugurtha, Srinivas S; Self, Debbie R

    2015-01-01

    This paper focuses on an analysis of pedestrian and motorists' actions at sites with pedestrian hybrid beacons and assesses their effectiveness in improving the safety of pedestrians. Descriptive and statistical analyses (one-tail two-sample T-test and two-proportion Z-test) were conducted using field data collected during morning and evening peak hours at three study sites in the city of Charlotte, NC, before and after the installation of pedestrian hybrid beacons. Further, an analysis was conducted to assess the change in pedestrian and motorists' actions over time (before the installation; 1 month, 3 months, 6 months, and 12 months after the installation). Results showed an increase in average traffic speed at one of the pedestrian hybrid beacon sites while no specific trends were observed at the other two pedestrian hybrid beacon sites. A decrease in the number of motorists not yielding to pedestrians, pedestrians trapped in the middle of the street, and pedestrian-vehicle conflicts were observed at all the three pedestrian hybrid beacon sites. The installation of pedestrian hybrid beacons did not have a negative effect on pedestrian actions at two out of the three sites. Improvements seem to be relatively more consistent 3 months after the installation of the pedestrian hybrid beacon.

  17. Phased-array radar design application of radar fundamentals

    Jeffrey, Thomas

    2009-01-01

    Phased-Array Radar Design is a text-reference designed for electrical engineering graduate students in colleges and universities as well as for corporate in-house training programs for radar design engineers, especially systems engineers and analysts who would like to gain hands-on, practical knowledge and skills in radar design fundamentals, advanced radar concepts, trade-offs for radar design and radar performance analysis.

  18. Doppler radar physiological sensing

    Lubecke, Victor M; Droitcour, Amy D; Park, Byung-Kwon; Singh, Aditya

    2016-01-01

    Presents a comprehensive description of the theory and practical implementation of Doppler radar-based physiological monitoring. This book includes an overview of current physiological monitoring techniques and explains the fundamental technology used in remote non-contact monitoring methods. Basic radio wave propagation and radar principles are introduced along with the fundamentals of physiological motion and measurement. Specific design and implementation considerations for physiological monitoring radar systems are then discussed in detail. The authors address current research and commercial development of Doppler radar based physiological monitoring for healthcare and other applications.

  19. Radar Signature Calculation Facility

    Federal Laboratory Consortium — FUNCTION: The calculation, analysis, and visualization of the spatially extended radar signatures of complex objects such as ships in a sea multipath environment and...

  20. Easy-to-Build Satellite Beacon Receiver for Propagation Experimentation at Millimeter Bands

    F. Machado

    2014-04-01

    Full Text Available This paper describes the design and development of a digital satellite beacon receiver for propagation experimentation. Satellite beacons are frequently available for pointing large antennas, but such signals can be used for measuring rain attenuation and other phenomena as, for example, tropospheric scintillation. A fairly inexpensive beacon receiver has been built using off-the-shelf parts. This instrument is not at all bulky making it suitable for easy transportation. This article analyzes the receiver specifications, describes in detail its structure and presents some operational test results.

  1. Tight Bounds for Beacon-Based Coverage in Simple Rectilinear Polygons

    Bae, Sang Won; Shin, Chan-Su; Vigneron, Antoine E.

    2016-01-01

    We establish tight bounds for beacon-based coverage problems. In particular, we show that $$\\lfloor \\frac{n}{6} \\rfloor $$⌊n6⌋ beacons are always sufficient and sometimes necessary to cover a simple rectilinear polygon P with n vertices. When P is monotone and rectilinear, we prove that this bound becomes $$\\lfloor \\frac{n+4}{8} \\rfloor $$⌊n+48⌋. We also present an optimal linear-time algorithm for computing the beacon kernel of P.

  2. Tight Bounds for Beacon-Based Coverage in Simple Rectilinear Polygons

    Bae, Sang Won

    2016-03-21

    We establish tight bounds for beacon-based coverage problems. In particular, we show that $$\\\\lfloor \\\\frac{n}{6} \\ floor $$⌊n6⌋ beacons are always sufficient and sometimes necessary to cover a simple rectilinear polygon P with n vertices. When P is monotone and rectilinear, we prove that this bound becomes $$\\\\lfloor \\\\frac{n+4}{8} \\ floor $$⌊n+48⌋. We also present an optimal linear-time algorithm for computing the beacon kernel of P.

  3. Radar Plan Position Indicator Scope

    National Oceanic and Atmospheric Administration, Department of Commerce — Radar Plan Position Indicator Scope is the collection of weather radar imagery for the period prior to the beginning of the Next Generation Radar (NEXRAD) system...

  4. Combined radar and telemetry system

    Rodenbeck, Christopher T.; Young, Derek; Chou, Tina; Hsieh, Lung-Hwa; Conover, Kurt; Heintzleman, Richard

    2017-08-01

    A combined radar and telemetry system is described. The combined radar and telemetry system includes a processing unit that executes instructions, where the instructions define a radar waveform and a telemetry waveform. The processor outputs a digital baseband signal based upon the instructions, where the digital baseband signal is based upon the radar waveform and the telemetry waveform. A radar and telemetry circuit transmits, simultaneously, a radar signal and telemetry signal based upon the digital baseband signal.

  5. Aspects of Radar Polarimetry

    LÜNEBURG, Ernst

    2002-01-01

    This contribution is a tutorial introduction to the phenomenological theory of radar polarimetry for the coherent scatter case emphasizing monostatic backscattering and forward scattering (transmission). Characteristic similarities and differences between radar polarimetry and optical polarimetry and the role of linear and antilinear operators (time-reversal) are pointed out and typical polarimetric invariants are identified.

  6. Java Radar Analysis Tool

    Zaczek, Mariusz P.

    2005-01-01

    Java Radar Analysis Tool (JRAT) is a computer program for analyzing two-dimensional (2D) scatter plots derived from radar returns showing pieces of the disintegrating Space Shuttle Columbia. JRAT can also be applied to similar plots representing radar returns showing aviation accidents, and to scatter plots in general. The 2D scatter plots include overhead map views and side altitude views. The superposition of points in these views makes searching difficult. JRAT enables three-dimensional (3D) viewing: by use of a mouse and keyboard, the user can rotate to any desired viewing angle. The 3D view can include overlaid trajectories and search footprints to enhance situational awareness in searching for pieces. JRAT also enables playback: time-tagged radar-return data can be displayed in time order and an animated 3D model can be moved through the scene to show the locations of the Columbia (or other vehicle) at the times of the corresponding radar events. The combination of overlays and playback enables the user to correlate a radar return with a position of the vehicle to determine whether the return is valid. JRAT can optionally filter single radar returns, enabling the user to selectively hide or highlight a desired radar return.

  7. Determination of radar MTF

    Chambers, D. [Lawrence Livermore National Lab., CA (United States)

    1994-11-15

    The ultimate goal of the Current Meter Array (CMA) is to be able to compare the current patterns detected with the array with radar images of the water surface. The internal wave current patterns modulate the waves on the water surface giving a detectable modulation of the radar cross-section (RCS). The function relating the RCS modulations to the current patterns is the Modulation Transfer Function (MTF). By comparing radar images directly with co-located CMA measurements the MTF can be determined. In this talk radar images and CMA measurements from a recent experiment at Loch Linnhe, Scotland, will be used to make the first direct determination of MTF for an X and S band radar at low grazing angles. The technical problems associated with comparing radar images to CMA data will be explained and the solution method discussed. The results suggest the both current and strain rate contribute equally to the radar modulation for X band. For S band, the strain rate contributes more than the current. The magnitude of the MTF and the RCS modulations are consistent with previous estimates when the wind is blowing perpendicular to the radar look direction.

  8. Design and Implementation of Distress Prevention System using a Beacon

    Lee Imsu

    2016-01-01

    Full Text Available It was proven that human accidents due to mountain climbing occupy large proportion of recently occurred man-made disasters. This paper designed and implemented an application that tells users about a variety of accidents that frequently occur in mountain and shows dynamic information about mountain climbing. It designed ‘distress prevention system using beacon’. When using beacon, it can dynamically express information without using GPS. It has advantage of supporting BLE and has little Smartphone battery consumption. The application was developed based on Android as a prototype. We expect that the application developed in this paper can contribute to the protection of precious lives by helping quick rescue in case of emergency such as distress. Manager of mountain can control data regarding the mountain climbing accident where the related functions are provided through view and user authority setup in DBMS.

  9. Beacons of discovery the worldwide science of particle physics

    International Committee for Future Accelerators (ICFA)

    2011-01-01

    To discover what our world is made of and how it works at the most fundamental level is the challenge of particle physics. The tools of particle physics—experiments at particle accelerators and underground laboratories, together with observations of space—bring opportunities for discovery never before within reach. Thousands of scientists from universities and laboratories around the world collaborate to design, build and use unique detectors and accelerators to explore the fundamental physics of matter, energy, space and time. Together, in a common world-wide program of discovery, they provide a deep understanding of the world around us and countless benefits to society. Beacons of Discovery presents a vision of the global science of particle physics at the dawn of a new light on the mystery and beauty of the universe.

  10. BEACON: An application of nodal methods for operational support

    Boyd, W.A.; Nguyen, T.Q.

    1992-01-01

    A practical application of nodal methods is on-line plant operational support. However, to enable plant personnel to take full advantage of a nodal model to support plant operations, (a) a core nodal model must always be up to date with the current core history and conditions, (b) the nodal methods must be fast enough to allow numerous core calculations to be performed in minutes to support engineering decisions, and (c) the system must be easily accessible to engineering personnel at the reactor, their offices, or any other location considered appropriate. A core operational support package developed by Westinghouse called BEACON (best estimate analysis of core operations - nuclear) has been installed at several plants. Results from these plants and numerous in-core flux maps analyzed have demonstrated the accuracy of the model and the effectiveness of the methodology

  11. Seamless Guidance System Combining GPS, BLE Beacon, and NFC Technologies

    Rung-Shiang Cheng

    2016-01-01

    Full Text Available Users rely increasingly on Location-Based Services (LBS and automated navigation/guidance systems nowadays. However, while such services are easily implemented in outdoor environments using Global Positioning System (GPS technology, a requirement still exists for accurate localization and guidance schemes in indoor settings. Accordingly, the present study proposes a system based on GPS, Bluetooth Low Energy (BLE beacons, and Near Field Communication (NFC technology. Through establishing graphic information and the design of algorithm, this study develops a guidance system for indoors and outdoors on smart phones, wishing to give user perfect smart life through this system. The proposed system is implemented on a smart phone and evaluated on a student campus environment. The experimental results confirm the ability of the proposed app to switch automatically from an outdoor mode to an indoor mode and to guide the user to requested target destination via the shortest possible route.

  12. NPP Grassland: Beacon Hill, U.K., 1972-1993, R1

    National Aeronautics and Space Administration — This data set contains two ASCII text files, one providing productivity measurements for a chalk grassland on Beacon Hill, West Sussex, U.K. (50.92 N, -0.85 W) and...

  13. Development of Aptamer Beacons for Antemortem Diagnosis of Chronic Wasting Disease

    Clinkenbeard, Kenneth D

    2005-01-01

    .... Once selected, the CWD aptamers will be configured as aptamer beacons that can act as molecular switches to turn "on" a novel and highly sensitive diagnostic technology termed amplifying fluorescing polymer...

  14. Development of Aptamer Beacons for Antemortem Diagnosis of Chronic Wasting Disease

    Clinkenbeard, Kenneth

    2004-01-01

    .... Once selected, the CWD aptamers will be configured as aptamer beacons that can act as molecular switches to turn on a novel and highly sensitive diagnostic technology termed amplifying fluorescing polymer. Objective...

  15. Evaluation of light-emitting diode beacon light fixtures : final report.

    2009-12-01

    Rotating beacons containing filament light sources have long been used on highway maintenance trucks : to indicate the presence of the truck to other drivers. Because of advances in light-emitting diode (LED) : technologies, flashing lights containin...

  16. Highly sensitive and rapid bacteria detection using molecular beacon-Au nanoparticles hybrid nanoprobes.

    Cao, Jing; Feng, Chao; Liu, Yan; Wang, Shouyu; Liu, Fei

    2014-07-15

    Since many diseases are caused by pathogenic bacterial infections, accurate and rapid detection of pathogenic bacteria is in urgent need to timely apply appropriate treatments and to reduce economic costs. To end this, we designed molecular beacon-Au nanoparticle hybrid nanoprobes to improve the bacterial detection efficiency and sensitivity. Here, we show that the designed molecular beacon modified Au nanoparticles could specifically recognize synthetic DNAs targets and can readily detect targets in clinical samples. Moreover, the hybrid nanoprobes can recognize Escherichia coli within an hour at a concentration of 10(2) cfu/ml, which is 1000-folds sensitive than using molecular beacon directly. Our results show that the molecular beacon-Au nanoparticle hybrid nanoprobes have great potential in medical and biological applications. Copyright © 2014 Elsevier B.V. All rights reserved.

  17. Multi-kW Uplink Fiber-Laser Beacon with Agile Signal Format, Phase II

    National Aeronautics and Space Administration —  Laser beacons with scalable powers are needed for ground to deep-space optical communication uplinks. They serve as absolute reference for tracking of spacecraft...

  18. Multi-kW Uplink Fiber-Laser Beacon with Agile Signal Format, Phase I

    National Aeronautics and Space Administration — Uplink Laser Beacons for deep-space communication, can benefit greatly from migration to the 1010-1030nm wavelengths, via use of Silicon-APDs on the spacecraft...

  19. High-throughput SNP genotyping: combining tag SNPs and molecular beacons

    Barreiro, LB

    2009-10-01

    Full Text Available In the last decade, molecular beacons have emerged to become a widely used tool in the multiplex typing of single nucleotide polymorphisms (SNPs). Improvements in detection technologies in instrumentation and chemistries to label these probes have...

  20. Principles of modern radar radar applications

    Scheer, James A

    2013-01-01

    Principles of Modern Radar: Radar Applications is the third of the three-volume seriesof what was originally designed to be accomplished in one volume. As the final volumeof the set, it finishes the original vision of a complete yet bounded reference for radartechnology. This volume describes fifteen different system applications or class ofapplications in more detail than can be found in Volumes I or II.As different as the applications described, there is a difference in how these topicsare treated by the authors. Whereas in Volumes I and II there is strict adherence tochapter format and leve

  1. BEACON: A Summary Framework to Overcome Potential Reimbursement Hurdles.

    Dunlop, William C N; Mullins, C Daniel; Pirk, Olaf; Goeree, Ron; Postma, Maarten J; Enstone, Ashley; Heron, Louise

    2016-10-01

    To provide a framework for addressing payers' criteria during the development of pharmaceuticals. A conceptual framework was presented to an international health economic expert panel for discussion. A structured literature search (from 2010 to May 2015), using the following databases in Ovid: Medline(®) and Medline(®) In-Process (PubMed), Embase (Ovid), EconLit (EBSCOhost) and the National Health Service Economic Evaluation Database (NHS EED), and a 'grey literature' search, were conducted to identify existing criteria from the payer perspective. The criteria assessed by existing frameworks and guidelines were collated; the most commonly reported criteria were considered for inclusion in the framework. A mnemonic was conceived as a memory aide to summarise these criteria. Overall, 41 publications were identified as potentially relevant to the objective. Following further screening, 26 were excluded upon full-text review on the basis of no framework presented (n = 13), redundancy (n = 11) or abstract only (n = 2). Frameworks that captured criteria developed for or utilised by the pharmaceutical industry (n = 5) and reimbursement guidance (n = 10) were reviewed. The most commonly identified criteria-unmet need/patient burden, safety, efficacy, quality-of-life outcomes, environment, evidence quality, budget impact and comparator-were incorporated into the summary framework. For ease of communication, the following mnemonic was developed: BEACON (Burden/target population, Environment, Affordability/value, Comparator, Outcomes, Number of studies/quality of evidence). The BEACON framework aims to capture the 'essence' of payer requirements by addressing the most commonly described criteria requested by payers regarding the introduction of a new pharmaceutical.

  2. Remote tracking of a magnetic receiver using low frequency beacons

    Sheinker, Arie; Ginzburg, Boris; Salomonski, Nizan; Frumkis, Lev; Kaplan, Ben-Zion

    2014-01-01

    Low frequency magnetic fields feature high penetration ability, which allows communication, localization, and tracking in environments where radio or acoustic waves are blocked or distorted by multipath interferences. In the present work, we propose a method for tracking a magnetic receiver using beacons of low frequency magnetic field, where the receiver includes a tri-axial search-coil magnetometer. Measuring the beacons’ magnetic fields and calculating the total-field signals enables localization without restrictions on magnetometer orientation, allowing on-the-move tracking. The total-field signals are used by a global search method, e.g., simulated annealing (SA) algorithm, to localize the receiver. The magnetic field produced by each beacon has a dipole structure and is governed by the beacon’s position and magnetic moment. We have investigated two different methods for estimating beacons’ magnetic moments prior to localization. The first method requires directional measurements, whereas for the second method the total-field signal is used. Effectiveness of these methods has been proved in numerous field tests. In the present work, we introduce a method for tracking a moving receiver by successive localizations. Using previous localization as a starting point of the search method for the next localization can reduce execution time and chances for divergence. The proposed method has been tested using numerous computer simulations. Successful system operation has been verified in field conditions. The good tracking capability together with simple implementation makes the proposed method attractive for real-time, low power field applications, such as mobile robots navigation. (paper)

  3. Improving adherence to the Epic Beacon ambulatory workflow.

    Chackunkal, Ellen; Dhanapal Vogel, Vishnuprabha; Grycki, Meredith; Kostoff, Diana

    2017-06-01

    Computerized physician order entry has been shown to significantly improve chemotherapy safety by reducing the number of prescribing errors. Epic's Beacon Oncology Information System of computerized physician order entry and electronic medication administration was implemented in Henry Ford Health System's ambulatory oncology infusion centers on 9 November 2013. Since that time, compliance to the infusion workflow had not been assessed. The objective of this study was to optimize the current workflow and improve the compliance to this workflow in the ambulatory oncology setting. This study was a retrospective, quasi-experimental study which analyzed the composite workflow compliance rate of patient encounters from 9 to 23 November 2014. Based on this analysis, an intervention was identified and implemented in February 2015 to improve workflow compliance. The primary endpoint was to compare the composite compliance rate to the Beacon workflow before and after a pharmacy-initiated intervention. The intervention, which was education of infusion center staff, was initiated by ambulatory-based, oncology pharmacists and implemented by a multi-disciplinary team of pharmacists and nurses. The composite compliance rate was then reassessed for patient encounters from 2 to 13 March 2015 in order to analyze the effects of the determined intervention on compliance. The initial analysis in November 2014 revealed a composite compliance rate of 38%, and data analysis after the intervention revealed a statistically significant increase in the composite compliance rate to 83% ( p < 0.001). This study supports a pharmacist-initiated educational intervention can improve compliance to an ambulatory, oncology infusion workflow.

  4. Perancangan Prototipe Receiver Beacon Black Box Locator Acoustic 37,5 kHz Pingers

    RUSTAMAJI RUSTAMAJI; PAULINE RAHMIATI; SARAH PERMATASARI

    2016-01-01

    ABSTRAK Ketika suatu pesawat terbang mengalami kecelakaan terjatuh ke dalam air, maka lokasi keberadaannya dapat dideteksi oleh alat yang disebut receiver beacon black box locator acoustic (pingers receiver). Pingers receiver berfungsi untuk menerima sinyal dengan frekuensi 37,5 kHz ± 1 kHz dari pingers transmitter atau Underwater Locator Beacon (ULB) yang berada pada black box pesawat. Dalam penelitian ini dibuat perancangan pingers receiver yang tersusun dari rangkaian Band Pass Filter (BPF...

  5. Saturated fatty acids and fatty acid esters promote the polymorphic transition of clarithromycin metastable form I crystal.

    Watanabe, Miteki; Mizoguchi, Midori; Aoki, Hajime; Iwao, Yasunori; Noguchi, Shuji; Itai, Shigeru

    2016-10-15

    The phase transition of active pharmaceutical ingredients should be taken into account during manufacturing, processing- and storage, because different crystal forms lead to different physical properties of formulations. The phase transition of clarithromycin (CAM) metastable form I to stable form II was investigated on heating with additives such as fatty acids or fatty acid esters. Differential scanning calorimetry analyses revealed that when form I was heated with additives, the phase transition temperature of form I decreased close to the melting points of the additives. Powder X-ray diffraction analyses indicated the tentative presence of a non-crystalline component during the transition of form I to form II on heating with additives. These observations implied that CAM form I dissolved in the melted additives on heating and the dissolved CAM crystallized to form II. Reduction of transition temperatures in the presence of additives were also observed for the crystals of nifedipine form B and carbamazepine form III. These results suggested that the phenomena can be widely applicable for simultaneous crystalline phase transition and granulation using binder additives. Copyright © 2016 Elsevier B.V. All rights reserved.

  6. Serum inverts and improves the fluorescence response of an aptamer beacon to various vitamin D analytes.

    Bruno, John G; Carrillo, Maria P; Phillips, Taylor; Edge, Allison

    2012-01-01

    A dominant aptamer loop structure from a library of nearly 100 candidate aptamer sequences developed against immobilized 25-hydroxyvitamin D(3) (calcidiol) was converted into a 5'-TYE 665 and 3'-Iowa black-labelled aptamer beacon. The aptamer beacon exhibited a mild 'lights on' reaction in buffer as a function of increasing concentrations of several vitamin D analogues and metabolites, with a limit of detection of approximately 200 ng/mL, and was not specific for any particular congener. In 10% or 50% human serum, the same aptamer beacon inverted its fluorescence behaviour to become a more intense 'lights off' reaction with an improved limit of detection in the range 4-16 ng/mL. We hypothesized that this drastic change in fluorescence behaviour was due to the presence of creatinine and urea in serum, which might destabilize the quenched beacon, causing an increase in fluorescence followed by decreasing fluorescence as a function of vitamin D concentrations that may bind and quench increasingly greater fractions of the denatured beacons. However, the results of several control experiments in the presence of physiological or greater concentrations of creatinine and urea, alone or combined in buffer, failed to produce the beacon fluorescence inversion. Other possible mechanistic hypotheses are also discussed. Copyright © 2011 John Wiley & Sons, Ltd.

  7. An adaptive scheme for robot localization and mapping with dynamically configurable inter-beacon range measurements.

    Torres-González, Arturo; Martinez-de Dios, Jose Ramiro; Ollero, Anibal

    2014-04-25

    This work is motivated by robot-sensor network cooperation techniques where sensor nodes (beacons) are used as landmarks for range-only (RO) simultaneous localization and mapping (SLAM). This paper presents a RO-SLAM scheme that actuates over the measurement gathering process using mechanisms that dynamically modify the rate and variety of measurements that are integrated in the SLAM filter. It includes a measurement gathering module that can be configured to collect direct robot-beacon and inter-beacon measurements with different inter-beacon depth levels and at different rates. It also includes a supervision module that monitors the SLAM performance and dynamically selects the measurement gathering configuration balancing SLAM accuracy and resource consumption. The proposed scheme has been applied to an extended Kalman filter SLAM with auxiliary particle filters for beacon initialization (PF-EKF SLAM) and validated with experiments performed in the CONET Integrated Testbed. It achieved lower map and robot errors (34% and 14%, respectively) than traditional methods with a lower computational burden (16%) and similar beacon energy consumption.

  8. Supporting Beacon and Event-Driven Messages in Vehicular Platoons through Token-Based Strategies.

    Balador, Ali; Uhlemann, Elisabeth; Calafate, Carlos T; Cano, Juan-Carlos

    2018-03-23

    Timely and reliable inter-vehicle communications is a critical requirement to support traffic safety applications, such as vehicle platooning. Furthermore, low-delay communications allow the platoon to react quickly to unexpected events. In this scope, having a predictable and highly effective medium access control (MAC) method is of utmost importance. However, the currently available IEEE 802.11p technology is unable to adequately address these challenges. In this paper, we propose a MAC method especially adapted to platoons, able to transmit beacons within the required time constraints, but with a higher reliability level than IEEE 802.11p, while concurrently enabling efficient dissemination of event-driven messages. The protocol circulates the token within the platoon not in a round-robin fashion, but based on beacon data age, i.e., the time that has passed since the previous collection of status information, thereby automatically offering repeated beacon transmission opportunities for increased reliability. In addition, we propose three different methods for supporting event-driven messages co-existing with beacons. Analysis and simulation results in single and multi-hop scenarios showed that, by providing non-competitive channel access and frequent retransmission opportunities, our protocol can offer beacon delivery within one beacon generation interval while fulfilling the requirements on low-delay dissemination of event-driven messages for traffic safety applications.

  9. Supporting Beacon and Event-Driven Messages in Vehicular Platoons through Token-Based Strategies

    Ali Balador

    2018-03-01

    Full Text Available Timely and reliable inter-vehicle communications is a critical requirement to support traffic safety applications, such as vehicle platooning. Furthermore, low-delay communications allow the platoon to react quickly to unexpected events. In this scope, having a predictable and highly effective medium access control (MAC method is of utmost importance. However, the currently available IEEE 802.11p technology is unable to adequately address these challenges. In this paper, we propose a MAC method especially adapted to platoons, able to transmit beacons within the required time constraints, but with a higher reliability level than IEEE 802.11p, while concurrently enabling efficient dissemination of event-driven messages. The protocol circulates the token within the platoon not in a round-robin fashion, but based on beacon data age, i.e., the time that has passed since the previous collection of status information, thereby automatically offering repeated beacon transmission opportunities for increased reliability. In addition, we propose three different methods for supporting event-driven messages co-existing with beacons. Analysis and simulation results in single and multi-hop scenarios showed that, by providing non-competitive channel access and frequent retransmission opportunities, our protocol can offer beacon delivery within one beacon generation interval while fulfilling the requirements on low-delay dissemination of event-driven messages for traffic safety applications.

  10. Accelerated Adoption of Advanced Health Information Technology in Beacon Community Health Centers.

    Jones, Emily; Wittie, Michael

    2015-01-01

    To complement national and state-level HITECH Act programs, 17 Beacon communities were funded to fuel community-wide use of health information technology to improve quality. Health centers in Beacon communities received supplemental funding. This article explores the association between participation in the Beacon program and the adoption of electronic health records. Using the 2010-2012 Uniform Data System, trends in health information technology adoption among health centers located within and outside of Beacon communities were explored using differences in mean t tests and multivariate logistic regression. Electronic health record adoption was widespread and rapidly growing in all health centers, especially quality improvement functionalities: structured data capture, order and results management, and clinical decision support. Adoption lagged for functionalities supporting patient engagement, performance measurement, care coordination, and public health. The use of advanced functionalities such as care coordination grew faster in Beacon health centers, and Beacon health centers had 1.7 times higher odds of adopting health records with basic safety and quality functionalities in 2010-2012. Three factors likely underlie these findings: technical assistance, community-wide activation supporting health information exchange, and the layering of financial incentives. Additional technical assistance and community-wide activation is needed to support the use of functionalities that are currently lagging. © Copyright 2015 by the American Board of Family Medicine.

  11. Radar-to-Radar Interference Suppression for Distributed Radar Sensor Networks

    Wen-Qin Wang

    2014-01-01

    Full Text Available Radar sensor networks, including bi- and multi-static radars, provide several operational advantages, like reduced vulnerability, good system flexibility and an increased radar cross-section. However, radar-to-radar interference suppression is a major problem in distributed radar sensor networks. In this paper, we present a cross-matched filtering-based radar-to-radar interference suppression algorithm. This algorithm first uses an iterative filtering algorithm to suppress the radar-to-radar interferences and, then, separately matched filtering for each radar. Besides the detailed algorithm derivation, extensive numerical simulation examples are performed with the down-chirp and up-chirp waveforms, partially overlapped or inverse chirp rate linearly frequency modulation (LFM waveforms and orthogonal frequency division multiplexing (ODFM chirp diverse waveforms. The effectiveness of the algorithm is verified by the simulation results.

  12. Radar remote sensing in biology

    Moore, Richard K.; Simonett, David S.

    1967-01-01

    The present status of research on discrimination of natural and cultivated vegetation using radar imaging systems is sketched. The value of multiple polarization radar in improved discrimination of vegetation types over monoscopic radars is also documented. Possible future use of multi-frequency, multi-polarization radar systems for all weather agricultural survey is noted.

  13. Novel radar techniques and applications

    Klemm, Richard; Koch, Wolfgang

    2017-01-01

    Novel Radar Techniques and Applications presents the state-of-the-art in advanced radar, with emphasis on ongoing novel research and development and contributions from an international team of leading radar experts. This volume covers: Waveform diversity and cognitive radar and Target tracking and data fusion.

  14. Radar and electronic navigation

    Sonnenberg, G J

    2013-01-01

    Radar and Electronic Navigation, Sixth Edition discusses radar in marine navigation, underwater navigational aids, direction finding, the Decca navigator system, and the Omega system. The book also describes the Loran system for position fixing, the navy navigation satellite system, and the global positioning system (GPS). It reviews the principles, operation, presentations, specifications, and uses of radar. It also describes GPS, a real time position-fixing system in three dimensions (longitude, latitude, altitude), plus velocity information with Universal Time Coordinated (UTC). It is accur

  15. Wind farm radar study

    Davies, N.G.

    1995-01-01

    This report examines the possible degradations of radar performance that may be caused by the presence of a wind turbine generator within the radar coverage area. A brief literature survey reviews the previously published work, which is mainly concerned with degradation of broadcast TV reception. Estimates are made of wind turbine generator scattering cross-sections, and of the time and Doppler characteristics of the echo signals from representative wind turbine generator. The general characteristics of radar detection and tracking methods are described, and the behaviour of such systems in the presence of strong returns from a wind turbine generator (or an array of them) is discussed. (author)

  16. Radar observations of Mercury

    Harmon, J.K.; Campbell, D.B.

    1988-01-01

    Some of the radar altimetry profiles of Mercury obtained on the basis of data from the Arecibo Observatory are presented. In these measurements, the delay-Doppler method was used to measure altitudes along the Doppler equator, rather than to map radar reflectivity. The profiles, derived from observations made over a 6-yr period, provide extensive coverage over a restricted equatorial band and permit the identification of radar signatures for features as small as 50-km diameter craters and 1-km-high arcuate scarps. The data allowed identification of large-scale topographic features such as smooth plains subsidence zones and major highland regions

  17. Radar cross section

    Knott, Gene; Tuley, Michael

    2004-01-01

    This is the second edition of the first and foremost book on this subject for self-study, training, and course work. Radar cross section (RCS) is a comparison of two radar signal strengths. One is the strength of the radar beam sweeping over a target, the other is the strength of the reflected echo sensed by the receiver. This book shows how the RCS ?gauge? can be predicted for theoretical objects and how it can be measured for real targets. Predicting RCS is not easy, even for simple objects like spheres or cylinders, but this book explains the two ?exact? forms of theory so well that even a

  18. Radar Remote Sensing

    Rosen, Paul A.

    2012-01-01

    This lecture was just a taste of radar remote sensing techniques and applications. Other important areas include Stereo radar grammetry. PolInSAR for volumetric structure mapping. Agricultural monitoring, soil moisture, ice-mapping, etc. The broad range of sensor types, frequencies of observation and availability of sensors have enabled radar sensors to make significant contributions in a wide area of earth and planetary remote sensing sciences. The range of applications, both qualitative and quantitative, continue to expand with each new generation of sensors.

  19. Wind Profiling Radar

    National Oceanic and Atmospheric Administration, Department of Commerce — Clutter present in radar return signals as used for wind profiling is substantially removed by carrying out a Daubechies wavelet transformation on a time series of...

  20. Improved Laser Vibration Radar

    Hilaire, Pierre

    1998-01-01

    .... This thesis reconfigured an existing CO2 laboratory laser radar system that is capable of measuring the frequencies of vibration of a simulated target into a more compact and rugged form for field testing...

  1. Phased-array radars

    Brookner, E.

    1985-02-01

    The operating principles, technology, and applications of phased-array radars are reviewed and illustrated with diagrams and photographs. Consideration is given to the antenna elements, circuitry for time delays, phase shifters, pulse coding and compression, and hybrid radars combining phased arrays with lenses to alter the beam characteristics. The capabilities and typical hardware of phased arrays are shown using the US military systems COBRA DANE and PAVE PAWS as examples.

  2. Radar detection of Vesta

    Ostro, S.J.; Cornell University, Ithaca, N.Y.); Campbell, D.B.; Pettengill, G.H.

    1980-01-01

    Asteroid 4 Vesta was detected on November 6, 1979 with the Arecibo Observatory's S-band (12.6-cm-wavelength) radar. The echo power spectrum, received in the circular polarization opposite to that transmitted, yields a radar cross section of (0.2 + or - 0.1)pi a-squared, for a 272 km. The data are too noisy to permit derivation of Vesta's rotation period

  3. Downhole pulse radar

    Chang, Hsi-Tien

    1987-09-28

    A borehole logging tool generates a fast rise-time, short duration, high peak-power radar pulse having broad energy distribution between 30 MHz and 300 MHz through a directional transmitting and receiving antennas having barium titanate in the electromagnetically active region to reduce the wavelength to within an order of magnitude of the diameter of the antenna. Radar returns from geological discontinuities are sampled for transmission uphole. 7 figs.

  4. Quantum dot-based molecular beacon to monitor intracellular microRNAs.

    Lee, Jonghwan; Moon, Sung Ung; Lee, Yong Seung; Ali, Bahy A; Al-Khedhairy, Abdulaziz A; Ali, Daoud; Ahmed, Javed; Al Salem, Abdullah M; Kim, Soonhag

    2015-06-02

    Fluorescence monitoring of endogenous microRNA (miRNA or miR) activity related to neuronal development using nano-sized materials provides crucial information on miRNA expression patterns in a noninvasive manner. In this study, we report a new method to monitor intracellular miRNA124a using quantum dot-based molecular beacon (R9-QD-miR124a beacon). The R9-QD-miR124a beacon was constructed using QDs and two probes, miR124a-targeting oligomer and arginine rich cell-penetrating peptide (R9 peptide). The miR124a-targeting oligomer contains a miR124a binging sequence and a black hole quencher 1 (BHQ1). In the absence of target miR124a, the R9-QD-miR124a beacon forms a partial duplex beacon and remained in quenched state because the BHQ1 quenches the fluorescence signal of the R9-QD-miR124a beacon. The binding of miR124a to the miR124a binding sequence of the miR124a-targeting oligomer triggered the separation of the BHQ1 quencher and subsequent signal-on of a red fluorescence signal. Moreover, enhanced cellular uptake was achieved by conjugation with the R9 peptide, which resulted in increased fluorescent signal of the R9-QD-miR124a beacons in P19 cells during neurogenesis due to the endogenous expression of miR124a.

  5. Quantum Dot-Based Molecular Beacon to Monitor Intracellular MicroRNAs

    Jonghwan Lee

    2015-06-01

    Full Text Available Fluorescence monitoring of endogenous microRNA (miRNA or miR activity related to neuronal development using nano-sized materials provides crucial information on miRNA expression patterns in a noninvasive manner. In this study, we report a new method to monitor intracellular miRNA124a using quantum dot-based molecular beacon (R9-QD-miR124a beacon. The R9-QD-miR124a beacon was constructed using QDs and two probes, miR124a-targeting oligomer and arginine rich cell-penetrating peptide (R9 peptide. The miR124a-targeting oligomer contains a miR124a binging sequence and a black hole quencher 1 (BHQ1. In the absence of target miR124a, the R9-QD-miR124a beacon forms a partial duplex beacon and remained in quenched state because the BHQ1 quenches the fluorescence signal of the R9-QD-miR124a beacon. The binding of miR124a to the miR124a binding sequence of the miR124a-targeting oligomer triggered the separation of the BHQ1 quencher and subsequent signal-on of a red fluorescence signal. Moreover, enhanced cellular uptake was achieved by conjugation with the R9 peptide, which resulted in increased fluorescent signal of the R9-QD-miR124a beacons in P19 cells during neurogenesis due to the endogenous expression of miR124a.

  6. 75 FR 76997 - Agency Information Collection Activities: Arrival and Departure Record (Forms I-94 and I-94W) and...

    2010-12-10

    ... DEPARTMENT OF HOMELAND SECURITY U.S. Customs and Border Protection Agency Information Collection Activities: Arrival and Departure Record (Forms I-94 and I-94W) and Electronic System for Travel Authorization AGENCY: U.S. Customs and Border Protection, Department of Homeland Security ACTION: 30-Day notice...

  7. 76 FR 44349 - Agency Information Collection Activities: Arrival and Departure Record (Forms I-94 and I-94W) and...

    2011-07-25

    ... DEPARTMENT OF HOMELAND SECURITY U.S. Customs and Border Protection Agency Information Collection Activities: Arrival and Departure Record (Forms I-94 and I-94W) and Electronic System for Travel Authorization AGENCY: U.S. Customs and Border Protection, Department of Homeland Security ACTION: 30-day notice...

  8. In Situ Monitoring and Modeling of the Solution-Mediated Polymorphic Transformation of Rifampicin: From Form II to Form I.

    Guo, Nannan; Hou, Baohong; Wang, Na; Xiao, Yan; Huang, Jingjing; Guo, Yanmei; Zong, Shuyi; Hao, Hongxun

    2018-01-01

    In this article, the solution-mediated polymorphic transformation of rifampicin was investigated and simulated in 3 solvents at 30°C. The solid-state form I and form II of rifampicin was characterized by powder X-ray diffraction, scanning electron microscopy, thermogravimetric analysis, Raman spectroscopy, and Fourier transform infrared spectroscopy (FTIR). To explore the relative stability, solubility data of form I and form II of rifampicin in butan-1-ol were determined using a dynamical method. In addition, Raman spectroscopy and focused beam reflectance measurement were used to in situ monitor the transformation of rifampicin from form II to form I. The liquid state concentration of rifampicin was measured by UV spectroscopic method. To investigate the effect of solvent on transformation, the transformation experiments were carried out in 3 solvents. Furthermore, a mathematical model was built to describe the kinetics of dissolution, nucleation, and growth processes during transformation by using experimental data. By combination of experimental and simulation results, it was found that the transformation process of rifampicin is controlled by dissolution of form II in heptane, whereas the transformation in hexane and octane was firstly controlled by dissolution of solid-state form and then controlled by growth of form I. Copyright © 2018 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.

  9. 78 FR 5477 - Agency Information Collection Activities: Inter-Agency Alien Witness and Informant Record, Form I...

    2013-01-25

    ...-0046] Agency Information Collection Activities: Inter-Agency Alien Witness and Informant Record, Form I... collection. (2) Title of the Form/Collection: Inter-Agency Alien Witness and Informant Record. (3) Agency...- 854 is used by law enforcement agencies to bring alien witnesses and informants to the United States...

  10. 77 FR 61776 - Agency Information Collection Activities: Petition for Alien Fiancé(e), Form I-129F, Revision of...

    2012-10-11

    ...-0001] Agency Information Collection Activities: Petition for Alien Fianc[eacute](e), Form I-129F.../Collection: Petition for Alien Fianc[eacute](e). (3) Agency form number, if any, and the applicable component... United States in order to petition for an alien fianc[eacute](e), spouse, or his/her children. (5) An...

  11. Practical Fingerprinting Localization for Indoor Positioning System by Using Beacons

    Santosh Subedi

    2017-01-01

    Full Text Available Recent developments in the fields of smartphones and wireless communication technologies such as beacons, Wi-Fi, and ultra-wideband have made it possible to realize indoor positioning system (IPS with a few meters of accuracy. In this paper, an improvement over traditional fingerprinting localization is proposed by combining it with weighted centroid localization (WCL. The proposed localization method reduces the total number of fingerprint reference points over the localization space, thus minimizing both the time required for reading radio frequency signals and the number of reference points needed during the fingerprinting learning process, which eventually makes the process less time-consuming. The proposed positioning has two major steps of operation. In the first step, we have realized fingerprinting that utilizes lightly populated reference points (RPs and WCL individually. Using the location estimated at the first step, WCL is run again for the final location estimation. The proposed localization technique reduces the number of required fingerprint RPs by more than 40% compared to normal fingerprinting localization method with a similar localization estimation error.

  12. Optical Fiber Nanotips Coated with Molecular Beacons for DNA Detection

    Ambra Giannetti

    2015-04-01

    Full Text Available Optical fiber sensors, thanks to their compactness, fast response and real-time measurements, have a large impact in the fields of life science research, drug discovery and medical diagnostics. In recent years, advances in nanotechnology have resulted in the development of nanotools, capable of entering the single cell, resulting in new nanobiosensors useful for the detection of biomolecules inside living cells. In this paper, we provide an application of a nanotip coupled with molecular beacons (MBs for the detection of DNA. The MBs were characterized by hybridization studies with a complementary target to prove their functionality both free in solution and immobilized onto a solid support. The solid support chosen as substrate for the immobilization of the MBs was a 30 nm tapered tip of an optical fiber, fabricated by chemical etching. With this set-up promising results were obtained and a limit of detection (LOD of 0.57 nM was reached, opening up the possibility of using the proposed nanotip to detect mRNAs inside the cytoplasm of living cells.

  13. Quencher-free molecular beacon tethering 7-hydroxycoumarin detects targets through protonation/deprotonation.

    Kashida, Hiromu; Yamaguchi, Kyohei; Hara, Yuichi; Asanuma, Hiroyuki

    2012-07-15

    In this study, we synthesized a simple but efficient quencher-free molecular beacon tethering 7-hydroxycoumarin on D-threoninol based on its pK(a) change. The pK(a) of 7-hydroxycoumarin in a single strand was determined as 8.8, whereas that intercalated in the duplex was over 10. This large pK(a) shift (more than 1.2) upon hybridization could be attributed to the anionic and hydrophobic microenvironment inside the DNA duplex. Because 7-hydroxycoumarin quenches its fluorescence upon protonation, the emission intensity of the duplex at pH 8.5 was 1/15 that of the single strand. We applied this quenching mechanism to the preparation of a quencher-free molecular beacon by introducing the dye into the middle of the stem part. In the absence of the target, the stem region formed a duplex and fluorescence was quenched. However, when the target was added, the molecular beacon opened and the dye was deprotonated. As a result, the emission intensity of the molecular beacon with the target was 10 times higher than that without the target. Accordingly, a quencher-free molecular beacon utilizing the pK(a) change was successfully developed. Copyright © 2012 Elsevier Ltd. All rights reserved.

  14. Accurate beacon positioning method for satellite-to-ground optical communication.

    Wang, Qiang; Tong, Ling; Yu, Siyuan; Tan, Liying; Ma, Jing

    2017-12-11

    In satellite laser communication systems, accurate positioning of the beacon is essential for establishing a steady laser communication link. For satellite-to-ground optical communication, the main influencing factors on the acquisition of the beacon are background noise and atmospheric turbulence. In this paper, we consider the influence of background noise and atmospheric turbulence on the beacon in satellite-to-ground optical communication, and propose a new locating algorithm for the beacon, which takes the correlation coefficient obtained by curve fitting for image data as weights. By performing a long distance laser communication experiment (11.16 km), we verified the feasibility of this method. Both simulation and experiment showed that the new algorithm can accurately obtain the position of the centroid of beacon. Furthermore, for the distortion of the light spot through atmospheric turbulence, the locating accuracy of the new algorithm was 50% higher than that of the conventional gray centroid algorithm. This new approach will be beneficial for the design of satellite-to ground optical communication systems.

  15. A spiral wave front beacon for underwater navigation: transducer prototypes and testing.

    Dzikowicz, Benjamin R; Hefner, Brian T

    2012-05-01

    Transducers for acoustic beacons which can produce outgoing signals with wave fronts whose horizontal cross sections are circular or spiral are studied experimentally. A remote hydrophone is used to determine its aspect relative to the transducers by comparing the phase of the circular signal to the phase of the spiral signal. The transducers for a "physical-spiral" beacon are made by forming a strip of 1-3 piezocomposite transducer material around either a circular or spiral backing. A "phased-spiral" beacon is made from an array of transducer elements which can be driven either in phase or staggered out of phase so as to produce signals with either a circular or spiral wave front. Measurements are made to study outgoing signals and their usefulness in determining aspect angle. Vertical beam width is also examined and phase corrections applied when the hydrophone is out of the horizontal plane of the beacon. While numerical simulations indicate that the discontinuity in the physical-spiral beacon introduces errors into the measured phase, damping observed at the ends of the piezocomposite material is a more significant source of error. This damping is also reflected in laser Doppler vibrometer measurements of the transducer's surface velocity.

  16. Adaptive Beaconing in Mobility Aware Clustering Based MAC Protocol for Safety Message Dissemination in VANET

    Nishu Gupta

    2017-01-01

    Full Text Available Majority of research contributions in wireless access in vehicular environment (WAVE/IEEE 802.11p standard focus on life critical safety-related applications. These applications require regular status update of vehicle’s position referred to as beaconing. Periodic beaconing in vehicle to vehicle communication leads to severe network congestion in the communication channel. The condition worsens under high vehicular density where it impacts reliability and upper bound latency of safety messages. In this paper, WAVE compliant enhancement to the existing IEEE 802.11p protocol is presented which targets prioritized delivery of safety messages while simultaneously provisioning the dissemination of nonsafety messages. Proposed scheme relies on dynamic generation of beacons to mitigate channel congestion and inefficient bandwidth utilization by reducing transmission frequency of beacons. Through the use of clustering mechanism, different beaconing frequencies and different data transmission rates are assigned to prioritize vehicular mobility. Through extensive simulation results, the performance of the proposed approach is evaluated in terms of a wide range of quality of service (QoS parameters for two different transmission ranges. Results show that the proposed protocol provides significant enhancement and stability of the clustered topology in vehicular ad hoc network over existing standard and other protocols with similar applications.

  17. CAMEX-4 TOGA RADAR V1

    National Aeronautics and Space Administration — The TOGA radar dataset consists of browse and radar data collected from the TOGA radar during the CAMEX-4 experiment. TOGA is a C-band linear polarized doppler radar...

  18. A Measurement Study of BLE iBeacon and Geometric Adjustment Scheme for Indoor Location-Based Mobile Applications

    Jeongyeup Paek

    2016-01-01

    Full Text Available Bluetooth Low Energy (BLE and the iBeacons have recently gained large interest for enabling various proximity-based application services. Given the ubiquitously deployed nature of Bluetooth devices including mobile smartphones, using BLE and iBeacon technologies seemed to be a promising future to come. This work started off with the belief that this was true: iBeacons could provide us with the accuracy in proximity and distance estimation to enable and simplify the development of many previously difficult applications. However, our empirical studies with three different iBeacon devices from various vendors and two types of smartphone platforms prove that this is not the case. Signal strength readings vary significantly over different iBeacon vendors, mobile platforms, environmental or deployment factors, and usage scenarios. This variability in signal strength naturally complicates the process of extracting an accurate location/proximity estimation in real environments. Our lessons on the limitations of iBeacon technique lead us to design a simple class attendance checking application by performing a simple form of geometric adjustments to compensate for the natural variations in beacon signal strength readings. We believe that the negative observations made in this work can provide future researchers with a reference on how well of a performance to expect from iBeacon devices as they enter their system design phases.

  19. Improved margin utilization through the use of beacon power distribution surveillance

    Miller, R. Wade; Boyd, William A.

    2002-01-01

    Core Operations, including fuel cycle costs, can be significantly improved when state of the art surveillance techniques are employed for core power distribution monitoring. Core power distribution monitoring and Technical Specification surveillance are major operational issues at PWR's, particularly in plants with movable in core detectors. Even plants with fixed in core detectors do not always make use of the continuous data that is available. The BEACON TM system (Best Estimate Analysis of Core Operations - Nuclear) is a core monitoring and operational support package developed by Westinghouse for use in PWR plants with fixed or movable in core detectors. BEACON is a real time core monitoring system, which uses existing core instrumentation data and an on-line neutronics model to provide continuous monitored of the core power distribution information. With this information available the BEACON system can be used to continuously monitor core power margin for the plant Tech Spec surveillance requirements and for plant operational guidance

  20. Efficient Beacon Collision Resolution Procedure for IEEE 802.15.4 /Zigbee Wireless Personal Area Networks

    Bassam A. Zafar

    2017-04-01

    Full Text Available While IEEE 802.15.4/Zigbee is a promising technology for Wireless Personal Area Networks, several transmission problems are not yet resolved. In particular, the problem of beacon transmission interferences is causing the device connection loss to the network. In order to resolve this problem, we present a new distributed and reactive procedure for beacon collision resolution. It is an extension of the alignment procedure to reorganize randomly the beacon transmission time when a collision has occurred. The detail of the proposed procedure will be fully described and analyzed. The performance of our approach is performed by simulations. The results show that our approach reduces the collision probability and the device disconnections consequently.

  1. A beacon interval shifting scheme for interference mitigation in body area networks.

    Kim, Seungku; Kim, Seokhwan; Kim, Jin-Woo; Eom, Doo-Seop

    2012-01-01

    This paper investigates the issue of interference avoidance in body area networks (BANs). IEEE 802.15 Task Group 6 presented several schemes to reduce such interference, but these schemes are still not proper solutions for BANs. We present a novel distributed TDMA-based beacon interval shifting scheme that reduces interference in the BANs. A design goal of the scheme is to avoid the wakeup period of each BAN coinciding with other networks by employing carrier sensing before a beacon transmission. We analyze the beacon interval shifting scheme and investigate the proper back-off length when the channel is busy. We compare the performance of the proposed scheme with the schemes presented in IEEE 802.15 Task Group 6 using an OMNeT++ simulation. The simulation results show that the proposed scheme has a lower packet loss, energy consumption, and delivery-latency than the schemes of IEEE 802.15 Task Group 6.

  2. Analyte-Triggered DNA-Probe Release from a Triplex Molecular Beacon for Nanopore Sensing.

    Guo, Bingyuan; Sheng, Yingying; Zhou, Ke; Liu, Quansheng; Liu, Lei; Wu, Hai-Chen

    2018-03-26

    A new nanopore sensing strategy based on triplex molecular beacon was developed for the detection of specific DNA or multivalent proteins. The sensor is composed of a triplex-forming molecular beacon and a stem-forming DNA component that is modified with a host-guest complex. Upon target DNA hybridizing with the molecular beacon loop or multivalent proteins binding to the recognition elements on the stem, the DNA probe is released and produces highly characteristic current signals when translocated through α-hemolysin. The frequency of current signatures can be used to quantify the concentrations of the target molecules. This sensing approach provides a simple, quick, and modular tool for the detection of specific macromolecules with high sensitivity and excellent selectivity. It may find useful applications in point-of-care diagnostics with a portable nanopore kit in the future. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  3. Development of satellite position location system for aircraft and boat distress beacons

    Kahle, D. R.

    1982-01-01

    An international satellite system for the detection and location of distress beacons carried on aircraft and vessels is in its technical checkout phase. User demonstration and evaluation (D&E) will start in early 1983 and continue for two years. The D&E phase and a subsequent transition period will form the basis for improved search and rescue operations for the 1980's and beyond. The system, called COSPAS/SARSAT, has international participation involving the U.S., Canada, and France as SARSAT members and joint participation with the Soviet Union's COSPAS Project. Norway and the U.K. have recently joined as investigators. Average position location error of the satellite aided processing is expected to be from 10-20KM for the existing 121.5/243 MHz distress beacons and from 2-5KM for experimental beacons transmitting in the 406 MHz band.

  4. Radar Scan Methods in Modern Multifunctional Radars

    V. N. Skosyrev

    2014-01-01

    Full Text Available Considered urgent task of organizing the review space in modern multifunctional radar systems shall review the space in a wide range of elevation angles from minus 5 to 60-80 degrees and 360 degrees azimuth. MfRLS this type should provide an overview of the zone for a limited time (2-3 sec, detecting a wide range of subtle high and low-flying targets. The latter circumstance requires the organization to select targets against the background of reflections from the underlying surface and local objects (MP. When providing an overview of the space taken into account the need to increase not only the noise immunity, and survivability.Two variants of the review of space in the elevation plane in the solid-state AESA radar. In the first case the overview space narrow beam by one beam. In the second - the transfer of DNA is formed, covering the whole sector of responsibility in elevation and at the reception beam is formed in spetsvychislitele (CB as a result of the signal processing of digitized after emitters antenna web. The estimations of the parameters specific to the multifunction radar SAM air and missile defense. It is shown that in a number of practically important cases, preference should be given clearly one of the methods described review of space.The functional scheme with AESA radar for both variants of the review. Necessary to analyze their differences. Contains the problem of increasing the cost of MfRLS with digital beamforming DNA with increasing bandwidth probing signal being processed.Noted drawbacks of MfRLS with digital beamforming beam. Including: reduced accuracy of the coordinates at low elevation angles, the complexity of the organization of thermal regime of the solid element base using quasi-continuous signal with a low duty cycle. Shows their fundamentally unavoidable in the steppe and desert areas with uneven terrain (Kazakhstan, China, the Middle East.It is shown that for MfRLS working in strong clutter, more preferably

  5. Development of an aptamer beacon for detection of interferon-gamma.

    Tuleuova, Nazgul; Jones, Caroline N; Yan, Jun; Ramanculov, Erlan; Yokobayashi, Yohei; Revzin, Alexander

    2010-03-01

    Traditional antibody-based affinity sensing strategies employ multiple reagents and washing steps and are unsuitable for real-time detection of analyte binding. Aptamers, on the other hand, may be designed to monitor binding events directly, in real-time, without the need for secondary labels. The goal of the present study was to design an aptamer beacon for fluorescence resonance energy transfer (FRET)-based detection of interferon-gamma (IFN-gamma)--an important inflammatory cytokine. Variants of DNA aptamer modified with biotin moieties and spacers were immobilized on avidin-coated surfaces and characterized by surface plasmon resonance (SPR). The SPR studies showed that immobilization of aptamer via the 3' end resulted in the best binding IFN-gamma (K(d) = 3.44 nM). This optimal aptamer variant was then used to construct a beacon by hybridizing fluorophore-labeled aptamer with an antisense oligonucleotide strand carrying a quencher. SPR studies revealed that IFN-gamma binding with an aptamer beacon occurred within 15 min of analyte introduction--suggesting dynamic replacement of the quencher-complementary strand by IFN-gamma molecules. To further highlight biosensing applications, aptamer beacon molecules were immobilized inside microfluidic channels and challenged with varying concentration of analyte. Fluorescence microscopy revealed low fluorescence in the absence of analyte and high fluorescence after introduction of IFN-gamma. Importantly, unlike traditional antibody-based immunoassays, the signal was observed directly upon binding of analyte without the need for multiple washing steps. The surface immobilized aptamer beacon had a linear range from 5 to 100 nM and a lower limit of detection of 5 nM IFN-gamma. In conclusion, we designed a FRET-based aptamer beacon for monitoring of an inflammatory cytokine-IFN-gamma. In the future, this biosensing strategy will be employed to monitor dynamics of cytokine production by the immune cells.

  6. Building and strengthening infrastructure for data exchange: lessons from the beacon communities.

    Torres, Gretchen W; Swietek, Karen; Ubri, Petry S; Singer, Rachel F; Lowell, Kristina H; Miller, Wilhelmine

    2014-01-01

    The Beacon Community Cooperative Agreement Program supports interventions, including care-delivery innovations, provider performance measurement and feedback initiatives, and tools for providers and consumers to enhance care. Using a learning health system framework, we examine the Beacon Communities' processes in building and strengthening health IT (HIT) infrastructures, specifically successes and challenges in sharing patient information to improve clinical care. In 2010, the Office of the National Coordinator for Health Information Technology (ONC) launched the three-year program, which provided $250 million to 17 Beacon Communities to invest in HIT and health information exchange (HIE) infrastructure. Beacon Communities used this funding to develop and disseminate HIT-enabled quality improvement practices found effective in particular community and practice environments. NORC conducted 7 site visits, November 2012-March 2013, selecting Communities to represent diverse program features. From August-October 2013, NORC held discussions with the remaining 10 Communities. Following each visit or discussion, NORC summarized the information gathered, including transcripts, team observations, and other documents the Community provided, to facilitate a within-Community analysis of context and stakeholders, intervention strategies, enabling factors, and challenges. Although each Community designed and implemented data-sharing strategies in a unique environment, similar challenges and enabling factors emerged across the Beacons. From a learning health system perspective, their strategies to build and strengthen data-sharing infrastructures address the following crosscutting priorities: promoting technical advances and innovations by helping providers adapt EHRs for data exchange and performance measurement with customizable IT and offering technical support to smaller, independent providers; engaging key stakeholders; and fostering transparent governance and stewardship

  7. Results from the northern New Mexico satellite-beacon radio interferometer

    Carlos, R.; Jacobson, A.; Massey, R.; Wu, G.

    1994-01-01

    An interferometer described in the Boston, 1992, meeting of the Beacon Satellite Symposium has been in full operation for over a year now. It consists of four autonomous stations; three are in a triangle 70 km on a side and one is in the center. The stations receive the VHF beacons from two geosynchronous satellites, GOES-2 and ATS-3. The phases of the beacons are tracked at each station by referring them to an extremely stable rubidium oscillator. The studies of the two satellites are virtually separate experiments. The received phase of the beacon is retarded by the increased Total-Electron-Content of the dense regions of waves in the ionosphere. By comparing the phase history at four spatially separated stations, the authors can determine the two-dimensional propagation vector of the waves. This array is optimal for wavelengths of 70--300 km (periods of 300--3,000 seconds). Since the measurement is of the phase of the signal rather than the difference between the O-mode and X-mode phases, and since the beacons are in the VHF rather than in the L-band of GPS beacons, the array is very sensitive. It has a noise level of 10 13 electrons/m 2 , or 10 -4 of the normal daytime TEC. This has been verified by operating two stations in the same location, so that they saw the same ionosphere. The first interesting results from a year's study is that the authors do not see the same TID's when looking at the two satellites. One conclusion they draw is that they do not see evidence of ionospheric winds

  8. Time-Resolved Nucleic Acid Hybridization Beacons Utilizing Unimolecular and Toehold-Mediated Strand Displacement Designs.

    Massey, Melissa; Ancona, Mario G; Medintz, Igor L; Algar, W Russ

    2015-12-01

    Nucleic acid hybridization probes are sought after for numerous assay and imaging applications. These probes are often limited by the properties of fluorescent dyes, prompting the development of new probes where dyes are paired with novel or nontraditional luminescent materials. Luminescent terbium complexes are an example of such a material, and these complexes offer several unique spectroscopic advantages. Here, we demonstrate two nonstem-loop designs for light-up nucleic acid hybridization beacons that utilize time-resolved Förster resonance energy transfer (TR-FRET) between a luminescent Lumi4-Tb cryptate (Tb) donor and a fluorescent reporter dye, where time-resolved emission from the dye provides an analytical signal. Both designs are based on probe oligonucleotides that are labeled at their opposite termini with Tb and a fluorescent reporter dye. In one design, a probe is partially blocked with a quencher dye-labeled oligonucleotide, and target hybridization is signaled through toehold-mediated strand displacement and loss of a competitive FRET pathway. In the other design, the intrinsic folding properties of an unblocked probe are utilized in combination with a temporal mechanism for signaling target hybridization. This temporal mechanism is based on a recently elucidated "sweet spot" for TR-FRET measurements and exploits distance control over FRET efficiencies to shift the Tb lifetime within or outside the time-gated detection window for measurements. Both the blocked and unblocked beacons offer nanomolar (femtomole) detection limits, response times on the order of minutes, multiplexing through the use of different reporter dyes, and detection in complex matrices such as serum and blood. The blocked beacons offer better mismatch selectivity, whereas the unblocked beacons are simpler in design. The temporal mechanism of signaling utilized with the unblocked beacons also plays a significant role with the blocked beacons and represents a new and effective

  9. Molecular beacon anchored onto a graphene oxide substrate

    Darbandi, Arash; Datta, Debopam; Patel, Krunal; Lin, Gary; Stroscio, Michael A.; Dutta, Mitra

    2017-09-01

    In this article, we report a graphene oxide-based nanosensor incorporating semiconductor quantum dots linked to DNA-aptamers that functions as a ‘turn-off’ fluorescent nanosensor for detection of low concentrations of analytes. A specific demonstration of this turn-off aptasensor is presented for the case of the detection of mercury (II) ions. In this system, ensembles of aptamer-based quantum-dot sensors are anchored onto graphene oxide (GO) flakes which provide a platform for analyte detection in the vicinity of GO. Herein, the operation of this ensemble-based nanosensor is demonstrated for mercury ions, which upon addition of mercury, quenching of the emission intensity from the quantum dots is observed due to resonance energy transfer between quantum dots and the gold nanoparticle connected via a mercury target aptamer. A key result is that the usually dominant effect of quenching of the quantum dot due to close proximity to the GO can be reduced to negligible levels by using a linker molecule in conjunctions with the aptamer-based nanosensor. The effect of ionic concentration of the background matrix on the emission intensity was also investigated. The sensor system is found to be highly selective towards mercury and exhibits a linear behavior (r 2 > 0.99) in the nanomolar concentration range. The detection limit of the sensor towards mercury with no GO present was found to be 16.5 nM. With GO attached to molecular beacon via 14 base, 35 base, and 51 base long linker DNA, the detection limit was found to be 38.4 nM, 9.45 nM, and 11.38 nM; respectively.

  10. Ground penetrating radar

    Daniels, David J

    2004-01-01

    Ground-penetrating radar has come to public attention in recent criminal investigations, but has actually been a developing and maturing remote sensing field for some time. In the light of recent expansion of the technique to a wide range of applications, the need for an up-to-date reference has become pressing. This fully revised and expanded edition of the best-selling Surface-Penetrating Radar (IEE, 1996) presents, for the non-specialist user or engineer, all the key elements of this technique, which span several disciplines including electromagnetics, geophysics and signal processing. The

  11. Systems and Methods for Radar Data Communication

    Bunch, Brian (Inventor); Szeto, Roland (Inventor); Miller, Brad (Inventor)

    2013-01-01

    A radar information processing system is operable to process high bandwidth radar information received from a radar system into low bandwidth radar information that may be communicated to a low bandwidth connection coupled to an electronic flight bag (EFB). An exemplary embodiment receives radar information from a radar system, the radar information communicated from the radar system at a first bandwidth; processes the received radar information into processed radar information, the processed radar information configured for communication over a connection operable at a second bandwidth, the second bandwidth lower than the first bandwidth; and communicates the radar information from a radar system, the radar information communicated from the radar system at a first bandwidth.

  12. Experience and evaluation of advanced on-line core monitoring system 'BEACON' at IKATA site

    Fujitsuka, Nobumichi; Tanouchi, Hideyuki; Imamura, Yasuhiro; Mizobuchil, Daisuke

    1997-01-01

    Shikoku Electric Power Company installed BEACON core monitoring system into IKATA unit 3 in May 1994. During its first cycle of core operation, various operational data were obtained including data of some anomalous reactor conditions introduced for the test objective of the plant start-up. This paper presents the evaluation of the BEACON system capability based on this experience. The system functions such as core monitoring and anomaly detection, prediction of future reactor conditions and increased efficiency of core management activities are discussed. Our future plan to utilize the system is also presented. (authors)

  13. Code Development and Analysis Program: developmental checkout of the BEACON/MOD2A code

    Ramsthaler, J.A.; Lime, J.F.; Sahota, M.S.

    1978-12-01

    A best-estimate transient containment code, BEACON, is being developed by EG and G Idaho, Inc. for the Nuclear Regulatory Commission's reactor safety research program. This is an advanced, two-dimensional fluid flow code designed to predict temperatures and pressures in a dry PWR containment during a hypothetical loss-of-coolant accident. The most recent version of the code, MOD2A, is presently in the final stages of production prior to being released to the National Energy Software Center. As part of the final code checkout, seven sample problems were selected to be run with BEACON/MOD2A

  14. Optimal placement of range-only beacons for mobile robot localisation

    Burke, Michael G

    2011-11-01

    Full Text Available of the Euclidean distance between the position estimate (x; y; z) and the largest orthogo- nal standard deviations in 3D space, and is an improvement on the GDOP metric as it considers both off-diagonal covariance terms and individual beacon noise. The beacon... is the Euclidean distance between an accessed node and a goal. This results in the shortest route to a goal being determined. The cost of traversing to a node is typically the distance between nodes. However, by replacing this cost with the uncertainty metric...

  15. Molecular beacon – tool for real time studying gene activity in stem cells

    Ilieva, Mirolyuba; Dufva, Martin

    Cells respond to their internal genetic programs and external stimuli by modulating the synthesis of specific mRNAs. Direct observation of mRNA expression in living cells can provide valuable information with regards to understanding fundamental processes such cell differentiation, regeneration...... and cancerogenesis. Molecular beacon technology is based on fluorescence resonance energy transfer (FRET) and the complementary pairing principles. These fluorescent molecular probes are highly specific and sensitive and are one important tool in in vitro diagnostics. Here molecular beacons are used to follow...

  16. Human walking estimation with radar

    Dorp, Ph. van; Groen, F.C.A.

    2003-01-01

    Radar can be used to observe humans that are obscured by objects such as walls. These humans cannot be visually observed. The radar measurements are used to animate an obscured human in virtual reality. This requires detailed information about the motion. The radar measurements give detailed

  17. Netted LPI RADARs

    2011-09-01

    CHALLENGES ............................66 1. Radar Processing Gain ........................66 2. High Sensitivity Requirement .................68 B...Relationship Between Network Space and Challenges .....................................127 Figure 42. Maneuverability................................129...virtually any kind of terrain. It has five modes: Normal, Weather, ECCM, LPI, and Very Low Clearance ( VLC ). Pictures of the LANTIRN pod aboard and F-16

  18. Geologic map of the Beacon Rock quadrangle, Skamania County, Washington

    Evarts, Russell C.; Fleck, Robert J.

    2017-06-06

    The Beacon Rock 7.5′ quadrangle is located approximately 50 km east of Portland, Oregon, on the north side of the Columbia River Gorge, a scenic canyon carved through the axis of the Cascade Range by the Columbia River. Although approximately 75,000 people live within the gorge, much of the region remains little developed and is encompassed by the 292,500-acre Columbia River Gorge National Scenic Area, managed by a consortium of government agencies “to pro­tect and provide for the enhancement of the scenic, cultural, recreational and natural resources of the Gorge and to protect and support the economy of the Columbia River Gorge area.” As the only low-elevation corridor through the Cascade Range, the gorge is a critical regional transportation and utilities corridor (Wang and Chaker, 2004). Major state and national highways and rail lines run along both shores of the Columbia River, which also provides important water access to ports in the agricultural interior of the Pacific Northwest. Transmission lines carry power from hydroelectric facilities in the gorge and farther east to the growing urban areas of western Oregon and Washington, and natural-gas pipelines transect the corridor (Wang and Chaker, 2004). These lifelines are highly vulnerable to disruption by earthquakes, landslides, and floods. A major purpose of the work described here is to identify and map geologic hazards, such as faults and landslide-prone areas, to provide more accurate assessments of the risks associated with these features.The steep canyon walls of the map area reveal exten­sive outcrops of Miocene flood-basalt flows of the Columbia River Basalt Group capped by fluvial deposits of the ances­tral Columbia River, Pliocene lavas erupted from the axis of the Cascade arc to the east, and volcanic rocks erupted from numerous local vents. The Columbia River Basalt Group unconformably rests on a sequence of late Oligocene and early Miocene rocks of the ancestral Cascade volcanic arc

  19. The use of radar for bathymetry assessment

    Aardoom, J.H.; Greidanus, H.S.F.

    1998-01-01

    The bottom topography in shallow seas can be observed by air- and spaceborne imaging radar. Bathymetric information derived from radar data is limited in accuracy, but radar has a good spatial coverage. The accuracy can be increased by assimilating the radar imagery into existing or insitu gathered bathymetric data. The paper reviews the concepts of bathymetry assessment by radar, the radar imaging mechanism, and the possibilities and limitations of the use of radar data in rapid assessment.

  20. ClassBeacons: designing distributed visualization of teachers’ physical proximity in the classroom.

    An, P.; Bakker, S.; Ordanovski, S.; Taconis, R.; Eggen, J.H.

    2018-01-01

    Pengcheng An, Saskia Bakker, Sara Ordanovski, Ruurd Taconis, Berry Eggen. 2018 (accepted at Oct 2017). ClassBeacons: designing distributed visualization of teachers’ physical proximity in the classroom. In Proceedings of Tangible and Embodied Interaction, TEI 2018, Mar 18-21, 2018,

  1. Pedestrian hybrid beacon crosswalk system (PHB) or high-intensity activated crosswalk (HAWK).

    2014-11-01

    The Pedestrian Hybrid Beacon Crosswalk (PHB) is a type of traffic control system, used to aid : pedestrians safely crossing the street and to regulate traffic flow. This study examines the : success of the first PHB installed in the state of Vermont....

  2. Beacon satellite studies and modelling of total electron contents of the ionosphere

    Tyagi, T.R.

    1990-01-01

    An attempt is made to highlight some of the beacon satellite studies, particularly those relating to total electron content (TEC) and scintillations, with special attention to Indian subcontinent observations. The modelling of TEC is described. The scope of new experiments for specific problem is indicated. (author). 78 refs., 12 figs

  3. Improved fixation quality provided by a Bessel beacon in an adaptive optics system.

    Lambert, Andrew J; Daly, Elizabeth M; Dainty, Christopher J

    2013-07-01

    We investigate whether a structured probe beam that creates the beacon for use in a retinal imaging adaptive optics system can provide useful side effects. In particular we investigate whether a Bessel beam that is seen by the subject as a set of concentric rings has a dampening effect on fixation variations of the subject under observation. This calming effect would allow longer periods of observation, particularly for patients with abnormal fixation. An experimental adaptive optics system developed for retinal imaging is used to monitor the fluctuations in aberrations for artificial and human subjects. The probe beam is alternated between a traditional beacon and one provided by a Bessel beam created by SLM. Time-frequency analysis is used to indicate the differences in power and time variation during fixation depending on whether the Bessel beam or the traditional beacon is employed. Comparison is made with the response for an artificial eye to discount systemic variations. Significant evidence is accrued to indicate the reduced fluctuations in fixation when the Bessel beam is employed to create the beacon. © 2013 The Authors Ophthalmic & Physiological Optics © 2013 The College of Optometrists.

  4. The Effects of a Rectangular Rapid-Flashing Beacon on Vehicle Speed

    VanWagner, Michelle; Van Houten, Ron; Betts, Brian

    2011-01-01

    In 2008, nearly 31% of vehicle fatalities were related to failure to adhere to safe vehicle speeds (National Highway Traffic Safety Administration [NHTSA], 2009). The current study evaluated the effect of a rectangular rapid-flashing beacon (RRFB) triggered by excessive speed on vehicle speed using a combined alternating treatments and reversal…

  5. Beacon-Based Service Publishing Framework in Multiservice Wi-Fi Hotspots

    Di Sorte Dario

    2007-01-01

    Full Text Available In an expected future multiaccess and multiservice IEEE 802.11 environment, the problem of providing users with useful service-related information to support a correct rapid network selection is expected to become a very important issue. A feasible short-term 802.11-tailored working solution, compliant with existing equipment, is to publish service information encoded within the SSID information element within beacon frames. This makes it possible for an operator to implement service publishing in 802.11 networks while waiting for a standardized mechanism. Also, this straightforward approach has allowed us to evaluate experimentally the performance of a beacon-based service publishing solution. In fact, the main focus of the paper is indeed to present a quantitative comparison of service discovery times between the legacy scenario, where the user is forced to associate and authenticate with a network point of access to check its service offer, and the enhanced scenario where the set of service-related information is broadcasted within beacons. These discovery times are obtained by processing the results of a measurement campaign performed in a multiaccess/service 802.11 environment. This analysis confirms the effectiveness of the beacon-based approach. We also show that the cost in terms of wireless bandwidth consumption of such solution is low.

  6. Application of the BEACON-TSM system to the operation of PWR reactors

    Lozano, J. A.; Mildrum, C.; Serrano, J. F.

    2011-01-01

    BEACON-TSM is an advanced system of the operation support of PWR reactors that combines the capabilities of an advanced nodal neutronic model and the measures of the instrumentation available in plant to determine, accurately and continuously, the distribution of power in the core and the available margins to the limits of the beak factors.

  7. Beacon signal in transcranial color coded ultrasound: A sign for brain death

    Mehmet Akif Topçuoğlu

    2014-04-01

    Full Text Available A widely under-recognized brain-death confirming transcranial ultrasonography pattern resembling the red-blue beacon signal was demonstrated. Familiarity to this distinct and characteristic ultrasonic pattern seems to be important in the perspective of point-of-care neurological ultrasound use and knobology.

  8. Sequential strand displacement beacon for detection of DNA coverage on functionalized gold nanoparticles.

    Paliwoda, Rebecca E; Li, Feng; Reid, Michael S; Lin, Yanwen; Le, X Chris

    2014-06-17

    Functionalizing nanomaterials for diverse analytical, biomedical, and therapeutic applications requires determination of surface coverage (or density) of DNA on nanomaterials. We describe a sequential strand displacement beacon assay that is able to quantify specific DNA sequences conjugated or coconjugated onto gold nanoparticles (AuNPs). Unlike the conventional fluorescence assay that requires the target DNA to be fluorescently labeled, the sequential strand displacement beacon method is able to quantify multiple unlabeled DNA oligonucleotides using a single (universal) strand displacement beacon. This unique feature is achieved by introducing two short unlabeled DNA probes for each specific DNA sequence and by performing sequential DNA strand displacement reactions. Varying the relative amounts of the specific DNA sequences and spacing DNA sequences during their coconjugation onto AuNPs results in different densities of the specific DNA on AuNP, ranging from 90 to 230 DNA molecules per AuNP. Results obtained from our sequential strand displacement beacon assay are consistent with those obtained from the conventional fluorescence assays. However, labeling of DNA with some fluorescent dyes, e.g., tetramethylrhodamine, alters DNA density on AuNP. The strand displacement strategy overcomes this problem by obviating direct labeling of the target DNA. This method has broad potential to facilitate more efficient design and characterization of novel multifunctional materials for diverse applications.

  9. A Beacon Transmission Power Control Algorithm Based on Wireless Channel Load Forecasting in VANETs.

    Mo, Yuanfu; Yu, Dexin; Song, Jun; Zheng, Kun; Guo, Yajuan

    2015-01-01

    In a vehicular ad hoc network (VANET), the periodic exchange of single-hop status information broadcasts (beacon frames) produces channel loading, which causes channel congestion and induces information conflict problems. To guarantee fairness in beacon transmissions from each node and maximum network connectivity, adjustment of the beacon transmission power is an effective method for reducing and preventing channel congestion. In this study, the primary factors that influence wireless channel loading are selected to construct the KF-BCLF, which is a channel load forecasting algorithm based on a recursive Kalman filter and employs multiple regression equation. By pre-adjusting the transmission power based on the forecasted channel load, the channel load was kept within a predefined range; therefore, channel congestion was prevented. Based on this method, the CLF-BTPC, which is a transmission power control algorithm, is proposed. To verify KF-BCLF algorithm, a traffic survey method that involved the collection of floating car data along a major traffic road in Changchun City is employed. By comparing this forecast with the measured channel loads, the proposed KF-BCLF algorithm was proven to be effective. In addition, the CLF-BTPC algorithm is verified by simulating a section of eight-lane highway and a signal-controlled urban intersection. The results of the two verification process indicate that this distributed CLF-BTPC algorithm can effectively control channel load, prevent channel congestion, and enhance the stability and robustness of wireless beacon transmission in a vehicular network.

  10. Some measurements of total electron content made with the ATS-6 radio beacon

    Davies, K.; Degenhardt, W.; Hartmann, G.K.

    1978-01-01

    The paper deals with some measurements made with the radio beacon on board the ATS-6 satellite in the American and European sectors. Measurements of the slant electron content, the Faraday content, and the plasmaspheric (or residual) content, made under different geographic and geomagnetic conditions, are discussed and compared

  11. A Beacon Transmission Power Control Algorithm Based on Wireless Channel Load Forecasting in VANETs.

    Yuanfu Mo

    Full Text Available In a vehicular ad hoc network (VANET, the periodic exchange of single-hop status information broadcasts (beacon frames produces channel loading, which causes channel congestion and induces information conflict problems. To guarantee fairness in beacon transmissions from each node and maximum network connectivity, adjustment of the beacon transmission power is an effective method for reducing and preventing channel congestion. In this study, the primary factors that influence wireless channel loading are selected to construct the KF-BCLF, which is a channel load forecasting algorithm based on a recursive Kalman filter and employs multiple regression equation. By pre-adjusting the transmission power based on the forecasted channel load, the channel load was kept within a predefined range; therefore, channel congestion was prevented. Based on this method, the CLF-BTPC, which is a transmission power control algorithm, is proposed. To verify KF-BCLF algorithm, a traffic survey method that involved the collection of floating car data along a major traffic road in Changchun City is employed. By comparing this forecast with the measured channel loads, the proposed KF-BCLF algorithm was proven to be effective. In addition, the CLF-BTPC algorithm is verified by simulating a section of eight-lane highway and a signal-controlled urban intersection. The results of the two verification process indicate that this distributed CLF-BTPC algorithm can effectively control channel load, prevent channel congestion, and enhance the stability and robustness of wireless beacon transmission in a vehicular network.

  12. Analysis and Enhancement of IEEE 802.15.4e DSME Beacon Scheduling Model

    Kwang-il Hwang

    2014-01-01

    Full Text Available In order to construct a successful Internet of things (IoT, reliable network construction and maintenance in a sensor domain should be supported. However, IEEE 802.15.4, which is the most representative wireless standard for IoT, still has problems in constructing a large-scale sensor network, such as beacon collision. To overcome some problems in IEEE 802.15.4, the 15.4e task group proposed various different modes of operation. Particularly, the IEEE 802.15.4e deterministic and synchronous multichannel extension (DSME mode presents a novel scheduling model to solve beacon collision problems. However, the DSME model specified in the 15.4e draft does not present a concrete design model but a conceptual abstract model. Therefore, in this paper we introduce a DSME beacon scheduling model and present a concrete design model. Furthermore, validity and performance of DSME are evaluated through experiments. Based on experiment results, we analyze the problems and limitations of DSME, present solutions step by step, and finally propose an enhanced DSME beacon scheduling model. Through additional experiments, we prove the performance superiority of enhanced DSME.

  13. Scheduled MAC in Beacon Overlay Networks for Underwater Localization and Time-Synchronization

    van Kleunen, W.A.P.; Meratnia, Nirvana; Havinga, Paul J.M.

    2011-01-01

    In this article we introduce a MAC protocol designed for underwater localization and time-synchronisation. The MAC protocol assumes a network of static reference nodes and allows blind nodes to be localized by listening-only to the beacon messages. Such a system is known to be very scalable. We show

  14. Visual detection of STAT5B gene expression in living cell using the hairpin DNA modified gold nanoparticle beacon.

    Xue, Jianpeng; Shan, Lingling; Chen, Haiyan; Li, Yang; Zhu, Hongyan; Deng, Dawei; Qian, Zhiyu; Achilefu, Samuel; Gu, Yueqing

    2013-03-15

    Signal transducer and activator of transcription 5B (STAT5B) is an important protein in JAK-STAT signaling pathway that is responsible for the metastasis and proliferation of tumor cells. Determination of the STAT5B messenger Ribonucleic Acid (mRNA) relating to the STAT5B expression provides insight into the mechanism of tumor progression. In this study, we designed and used a special hairpin deoxyribonucleic acid (DNA) for human STAT5B mRNA to functionalize gold nanoparticles, which served as a beacon for detecting human STAT5B expression. Up to 90% quenching efficiency was achieved. Upon hybridizing with the target mRNA, the hairpin DNA modified gold nanoparticle beacons (hDAuNP beacons) release the fluorophores attached at 5' end of the oligonucleotide sequence. The fluorescence properties of the beacon before and after the hybridization with the complementary DNA were confirmed in vitro. The stability of hDAuNP beacons against degradation by DNase I and GSH indicated that the prepared beacon is stable inside cells. The detected fluorescence in MCF-7 cancer cells correlates with the specific STAT5B mRNA expression, which is consistent with the result from PCR measurement. Fluorescence microscopy showed that the hDAuNP beacons internalized in cells without using transfection agents, with intracellular distribution in the cytoplasm rather than the nucleus. The results demonstrated that this beacon could directly provide quantitative measurement of the intracellular STAT5B mRNA in living cells. Compared to the previous approaches, this beacon has advantages of higher target to background ratio of detection and an increased resistance to nuclease degradation. The strategy reported in this study is a promising approach for the intracellular measurement of RNA or protein expression in living cells, and has great potential in the study of drug screening and discovery. Copyright © 2012 Elsevier B.V. All rights reserved.

  15. Supplementary Material for: BEACON: automated tool for Bacterial GEnome Annotation ComparisON

    Kalkatawi, Manal M.; Alam, Intikhab; Bajic, Vladimir B.

    2015-01-01

    Abstract Background Genome annotation is one way of summarizing the existing knowledge about genomic characteristics of an organism. There has been an increased interest during the last several decades in computer-based structural and functional genome annotation. Many methods for this purpose have been developed for eukaryotes and prokaryotes. Our study focuses on comparison of functional annotations of prokaryotic genomes. To the best of our knowledge there is no fully automated system for detailed comparison of functional genome annotations generated by different annotation methods (AMs). Results The presence of many AMs and development of new ones introduce needs to: a/ compare different annotations for a single genome, and b/ generate annotation by combining individual ones. To address these issues we developed an Automated Tool for Bacterial GEnome Annotation ComparisON (BEACON) that benefits both AM developers and annotation analysers. BEACON provides detailed comparison of gene function annotations of prokaryotic genomes obtained by different AMs and generates extended annotations through combination of individual ones. For the illustration of BEACONâ s utility, we provide a comparison analysis of multiple different annotations generated for four genomes and show on these examples that the extended annotation can increase the number of genes annotated by putative functions up to 27 %, while the number of genes without any function assignment is reduced. Conclusions We developed BEACON, a fast tool for an automated and a systematic comparison of different annotations of single genomes. The extended annotation assigns putative functions to many genes with unknown functions. BEACON is available under GNU General Public License version 3.0 and is accessible at: http://www.cbrc.kaust.edu.sa/BEACON/ .

  16. Stability hierarchy between Piracetam forms I, II, and III from experimental pressure-temperature diagrams and topological inferences.

    Toscani, Siro; Céolin, René; Minassian, Léon Ter; Barrio, Maria; Veglio, Nestor; Tamarit, Josep-Lluis; Louër, Daniel; Rietveld, Ivo B

    2016-01-30

    The trimorphism of the active pharmaceutical ingredient piracetam is a famous case of polymorphism that has been frequently revisited by many researchers. The phase relationships between forms I, II, and III were ambiguous because they seemed to depend on the heating rate of the DSC and on the history of the samples or they have not been observed at all (equilibrium II-III). In the present paper, piezo-thermal analysis and high-pressure differential thermal analysis have been used to elucidate the positions of the different solid-solid and solid-liquid equilibria. The phase diagram, involving the three solid phases, the liquid phase and the vapor phase, has been constructed. It has been shown that form III is the high-pressure, low-temperature form and the stable form at room temperature. Form II is stable under intermediary conditions and form I is the low pressure, high temperature form, which possesses a stable melting point. The present paper demonstrates the strength of the topological approach based on the Clapeyron equation and the alternation rule when combined with high-pressure measurements. Copyright © 2015 Elsevier B.V. All rights reserved.

  17. Comet radar explorer

    Farnham, Tony; Asphaug, Erik; Barucci, Antonella; Belton, Mike; Bockelee-Morvan, Dominique; Brownlee, Donald; Capria, Maria Teresa; Carter, Lynn; Chesley, Steve; Farnham, Tony; Gaskell, Robert; Gim, Young; Heggy, Essam; Herique, Alain; Klaasen, Ken; Kofman, Wlodek; Kreslavsky, Misha; Lisse, Casey; Orosei, Roberto; Plaut, Jeff; Scheeres, Dan

    The Comet Radar Explorer (CORE) is designed to perform a comprehensive and detailed exploration of the interior, surface, and inner coma structures of a scientifically impor-tant Jupiter family comet. These structures will be used to investigate the origins of cometary nuclei, their physical and geological evolution, and the mechanisms driving their spectacular activity. CORE is a high heritage spacecraft, injected by solar electric propulsion into orbit around a comet. It is capable of coherent deep radar imaging at decameter wavelengths, high resolution stereo color imaging, and near-IR imaging spectroscopy. Its primary objective is to obtain a high-resolution map of the interior structure of a comet nucleus at a resolution of ¿100 elements across the diameter. This structure shall be related to the surface geology and morphology, and to the structural details of the coma proximal to the nucleus. This is an ideal complement to the science from recent comet missions, providing insight into how comets work. Knowing the structure of the interior of a comet-what's inside-and how cometary activity works, is required before we can understand the requirements for a cryogenic sample return mission. But more than that, CORE is fundamental to understanding the origin of comets and their evolution in time. The mission is made feasible at low cost by the use of now-standard MARSIS-SHARAD reflec-tion radar imaging hardware and data processing, together with proven flight heritage of solar electric propulsion. Radar flight heritage has been demonstrated by the MARSIS radar on Mars Express (Picardi et al., Science 2005; Plaut et al., Science 2007), the SHARAD radar onboard the Mars Reconnaissance Orbiter (Seu et al., JGR 2007), and the LRS radar onboard Kaguya (Ono et al, EPS 2007). These instruments have discovered detailed subsurface structure to depths of several kilometers in a variety of terrains on Mars and the Moon. A reflection radar deployed in orbit about a comet

  18. A review of array radars

    Brookner, E.

    1981-10-01

    Achievements in the area of array radars are illustrated by such activities as the operational deployment of the large high-power, high-range-resolution Cobra Dane; the operational deployment of two all-solid-state high-power, large UHF Pave Paws radars; and the development of the SAM multifunction Patriot radar. This paper reviews the following topics: array radars steered in azimuth and elevation by phase shifting (phase-phase steered arrays); arrays steered + or - 60 deg, limited scan arrays, hemispherical coverage, and omnidirectional coverage arrays; array radars steering electronically in only one dimension, either by frequency or by phase steering; and array radar antennas which use no electronic scanning but instead use array antennas for achieving low antenna sidelobes.

  19. FMWC Radar for Breath Detection

    Suhr, Lau Frejstrup; Tafur Monroy, Idelfonso; Vegas Olmos, Juan José

    We report on the experimental demonstration of an FMCW radar operating in the 25.7 - 26.6 GHz range with a repetition rate of 500 sweeps per second. The radar is able to track the breathing rate of an adult human from a distance of 1 meter. The experiments have utilized a 50 second recording window...... to accurately track the breathing rate. The radar utilizes a saw tooth modulation format and a low latency receiver. A breath tracking radar is useful both in medical scenarios, diagnosing disorders such as sleep apnea, and for home use where the user can monitor its health. Breathing is a central part of every...... radar chip which, through the use of a simple modulation scheme, is able to measure the breathing rate of an adult human from a distance. A high frequency output makes sure that the radar cannot penetrate solid obstacles which is a wanted feature in private homes where people therefore cannot measure...

  20. Radar Image, Hokkaido, Japan

    2000-01-01

    The southeast part of the island of Hokkaido, Japan, is an area dominated by volcanoes and volcanic caldera. The active Usu Volcano is at the lower right edge of the circular Lake Toya-Ko and near the center of the image. The prominent cone above and to the left of the lake is Yotei Volcano with its summit crater. The city of Sapporo lies at the base of the mountains at the top of the image and the town of Yoichi -- the hometown of SRTM astronaut Mamoru Mohri -- is at the upper left edge. The bay of Uchiura-Wan takes up the lower center of the image. In this image, color represents elevation, from blue at the lowest elevations to white at the highest. The radar image has been overlaid to provide more details of the terrain. Due to a processing problem, an island in the center of this crater lake is missing and will be properly placed when further SRTM swaths are processed. The horizontal banding in this image is a processing artifact that will be removed when the navigation information collected by SRTM is fully calibrated. This image was acquired by the Shuttle Radar Topography Mission (SRTM) aboard the Space Shuttle Endeavour, launched on February 11, 2000. SRTM used the same radar instrument that comprised the Spaceborne Imaging Radar-C/X-Band Synthetic Aperture Radar (SIR-C/X-SAR) that flew twice on the Space Shuttle Endeavour in 1994. SRTM was designed to collect three-dimensional measurements of the Earth's surface. To collect the 3-D data, engineers added a 60-meter-long (200-foot) mast, installed additional C-band and X-band antennas, and improved tracking and navigation devices. The mission is a cooperative project between the National Aeronautics and Space Administration (NASA), the National Imagery and Mapping Agency (NIMA) of the U.S. Department of Defense (DoD), and the German and Italian space agencies. It is managed by NASA's Jet Propulsion Laboratory, Pasadena, CA, for NASA's Earth Science Enterprise, Washington, DC. Size: 100 by 150 kilometers (62

  1. Radar techniques using array antennas

    Wirth, Wulf-Dieter

    2013-01-01

    Radar Techniques Using Array Antennas is a thorough introduction to the possibilities of radar technology based on electronic steerable and active array antennas. Topics covered include array signal processing, array calibration, adaptive digital beamforming, adaptive monopulse, superresolution, pulse compression, sequential detection, target detection with long pulse series, space-time adaptive processing (STAP), moving target detection using synthetic aperture radar (SAR), target imaging, energy management and system parameter relations. The discussed methods are confirmed by simulation stud

  2. BEACON/MOD: a computer program for thermal-hydraulic analysis of nuclear reactor containments - user's manual

    Broadus, C.R.; Doyle, R.J.; James, S.W.; Lime, J.F.; Mings, W.J.

    1980-04-01

    The BEACON code is a best-estimate, advanced containment code designed to perform a best-estimate analysis of the flow of a mixture of air, water, and steam in a nuclear reactor containment system under loss-of-coolant accident conditions. The code can simulate two-component, two-phase fluid flow in complex geometries using a combination of two-dimensional, one-dimensional, and lumped-parameter representations for the various parts of the system. The current version of BEACON, which is designated BEACON/MOD3, contains mass and heat transfer models for wall film and wall conduction. It is suitable for the evaluation of short-term transients in dry-containment systems. This manual describes the models employed in BEACON/MOD3 and specifies code implementation requirements. It provides application information for input data preparation and for output data interpretation

  3. BEACON/MOD2A analysis of the Arkansas-1 reactor cavity during a hypothetical hot leg break

    Ramsthaler, J.A.

    1979-01-01

    As part of the evaluation of the new MOD2A version of the BEACON code, the Arkansas-1 reactor cavity was modeled during a hypothetical loss-of-coolant accident. Results of the BEACON analysis were compared with results obtained previously with the COMPARE containment code. Studies were also made investigating some of the BEACON interphasic, timestep control, and wall heat transfer options to assure that these models were working properly and to observe their effects on the results. Descriptions of the Arkansas-1 reactor cavity, initial assumptions during the hypothetical LOCA, and methods of modeling with BEACON are presented. Some of the problems encountered in accurately modeling the penetrations surrounding the hot and cold leg pipes are also discussed

  4. Traveling-Wave Tube Amplifier Second Harmonic as Millimeter-Wave Beacon Source for Atmospheric Propagation Studies

    Simons, Rainee N.; Wintucky, Edwin G.

    2014-01-01

    This paper presents the design and test results of a CW millimeter-wave satellite beacon source, based on the second harmonic from a traveling-wave tube amplifier and utilizes a novel waveguide multimode directional coupler. A potential application of the beacon source is for investigating the atmospheric effects on Q-band (37-42 GHz) and V/W-band (71- 76 GHz) satellite-to-ground signals.

  5. Cleavable DNA-protein hybrid molecular beacon: A novel efficient signal translator for sensitive fluorescence anisotropy bioassay.

    Hu, Pan; Yang, Bin

    2016-01-15

    Due to its unique features such as high sensitivity, homogeneous format, and independence on fluorescent intensity, fluorescence anisotropy (FA) assay has become a hotspot of study in oligonucleotide-based bioassays. However, until now most FA probes require carefully customized structure designs, and thus are neither generalizable for different sensing systems nor effective to obtain sufficient signal response. To address this issue, a cleavable DNA-protein hybrid molecular beacon was successfully engineered for signal amplified FA bioassay, via combining the unique stable structure of molecular beacon and the large molecular mass of streptavidin. Compared with single DNA strand probe or conventional molecular beacon, the DNA-protein hybrid molecular beacon exhibited a much higher FA value, which was potential to obtain high signal-background ratio in sensing process. As proof-of-principle, this novel DNA-protein hybrid molecular beacon was further applied for FA bioassay using DNAzyme-Pb(2+) as a model sensing system. This FA assay approach could selectively detect as low as 0.5nM Pb(2+) in buffer solution, and also be successful for real samples analysis with good recovery values. Compatible with most of oligonucleotide probes' designs and enzyme-based signal amplification strategies, the molecular beacon can serve as a novel signal translator to expand the application prospect of FA technology in various bioassays. Copyright © 2015 Elsevier B.V. All rights reserved.

  6. Broadview Radar Altimetry Toolbox

    Garcia-Mondejar, Albert; Escolà, Roger; Moyano, Gorka; Roca, Mònica; Terra-Homem, Miguel; Friaças, Ana; Martinho, Fernando; Schrama, Ernst; Naeije, Marc; Ambrózio, Américo; Restano, Marco; Benveniste, Jérôme

    2017-04-01

    The universal altimetry toolbox, BRAT (Broadview Radar Altimetry Toolbox) which can read all previous and current altimetry missions' data, incorporates now the capability to read the upcoming Sentinel3 L1 and L2 products. ESA endeavoured to develop and supply this capability to support the users of the future Sentinel3 SAR Altimetry Mission. BRAT is a collection of tools and tutorial documents designed to facilitate the processing of radar altimetry data. This project started in 2005 from the joint efforts of ESA (European Space Agency) and CNES (Centre National d'Etudes Spatiales), and it is freely available at http://earth.esa.int/brat. The tools enable users to interact with the most common altimetry data formats. The BratGUI is the frontend for the powerful command line tools that are part of the BRAT suite. BRAT can also be used in conjunction with MATLAB/IDL (via reading routines) or in C/C++/Fortran via a programming API, allowing the user to obtain desired data, bypassing the dataformatting hassle. BRAT can be used simply to visualise data quickly, or to translate the data into other formats such as NetCDF, ASCII text files, KML (Google Earth) and raster images (JPEG, PNG, etc.). Several kinds of computations can be done within BRAT involving combinations of data fields that the user can save for posterior reuse or using the already embedded formulas that include the standard oceanographic altimetry formulas. The Radar Altimeter Tutorial, that contains a strong introduction to altimetry, shows its applications in different fields such as Oceanography, Cryosphere, Geodesy, Hydrology among others. Included are also "use cases", with step-by-step examples, on how to use the toolbox in the different contexts. The Sentinel3 SAR Altimetry Toolbox shall benefit from the current BRAT version. While developing the toolbox we will revamp of the Graphical User Interface and provide, among other enhancements, support for reading the upcoming S3 datasets and specific

  7. Doppler radar flowmeter

    Petlevich, Walter J.; Sverdrup, Edward F.

    1978-01-01

    A Doppler radar flowmeter comprises a transceiver which produces an audio frequency output related to the Doppler shift in frequency between radio waves backscattered from particulate matter carried in a fluid and the radiated radio waves. A variable gain amplifier and low pass filter are provided for amplifying and filtering the transceiver output. A frequency counter having a variable triggering level is also provided to determine the magnitude of the Doppler shift. A calibration method is disclosed wherein the amplifier gain and frequency counter trigger level are adjusted to achieve plateaus in the output of the frequency counter and thereby allow calibration without the necessity of being able to visually observe the flow.

  8. Imaging with Synthetic Aperture Radar

    Massonnet, Didier

    2008-01-01

    Describing a field that has been transformed by the recent availability of data from a new generation of space and airborne systems, the authors offer a synthetic geometrical approach to the description of synthetic aperture radar, one that addresses physicists, radar specialists, as well as experts in image processing.  

  9. Terahertz radar cross section measurements

    Iwaszczuk, Krzysztof; Heiselberg, Henning; Jepsen, Peter Uhd

    2010-01-01

    We perform angle- and frequency-resolved radar cross section (RCS) measurements on objects at terahertz frequencies. Our RCS measurements are performed on a scale model aircraft of size 5-10 cm in polar and azimuthal configurations, and correspond closely to RCS measurements with conventional radar...

  10. Performance indicators modern surveillance radar

    Nooij, P.N.C.; Theil, A.

    2014-01-01

    Blake chart computations are widely employed to rank detection coverage capabilities of competitive search radar systems. Developed for comparable 2D radar systems with a mechanically rotating reflector antenna, it was not necessary to regard update rate and plot quality in Blake's chart. To

  11. Visually Detecting the Variation of miR-301a Expression Using Gold Nanoparticle Beacon.

    Zhang, Ying; Li, Kai; Li, Dandan; Li, Changfeng; Zhang, Bin

    2018-02-01

    It is well known that microRNA-301a plays an important role in many diseases, as well as is overexpressed in human colon cancer and affects the process of tumorigenesis. Determination of the miR-301a expression provides insight into the mechanism of tumor progression. In this study, we designed a special hairpin deoxyribonucleic acid (DNA) for miR-301a to functionalize gold nanoparticles, which served as a beacon for detecting miR-301a expression. A-quenching efficiency up to 90% was achieved. The beacon we designed in this study can monitor the precise variation of miR-301a expression in vivo. The strategy reported in this study is a promising approach for the measurement of miRNA in living cells. Moreover, it has a great potential in the study of drug screening and discovery.

  12. Multi-Band Multi-Tone Tunable Millimeter-Wave Frequency Synthesizer For Satellite Beacon Transmitter

    Simons, Rainee N.; Wintucky, Edwin G.

    2016-01-01

    This paper presents the design and test results of a multi-band multi-tone tunable millimeter-wave frequency synthesizer, based on a solid-state frequency comb generator. The intended application of the synthesizer is in a satellite beacon transmitter for radio wave propagation studies at K-band (18 to 26.5 GHz), Q-band (37 to 42 GHz), and E-band (71 to 76 GHz). In addition, the architecture for a compact beacon transmitter, which includes the multi-tone synthesizer, polarizer, horn antenna, and power/control electronics, has been investigated for a notional space-to-ground radio wave propagation experiment payload on a small satellite. The above studies would enable the design of robust high throughput multi-Gbps data rate future space-to-ground satellite communication links.

  13. Topical MMP beacon enabled fluorescence-guided resection of oral carcinoma

    Burgess, Laura; Chen, Juan; Wolter, Nikolaus E.; Wilson, Brian; Zheng, Gang

    2016-01-01

    Each year almost 300,000 individuals worldwide are diagnosed with oral cancer, more than 90% of these being oral carcinoma [N. Engl. J. Med. 328, 184 19938417385]. Surgical resection is the standard of care, but accurate delineation of the tumor boundaries is challenging, resulting in either under-resection with risk of local recurrence or over-resection with increased functional loss and negative impact on quality of life. This study evaluates, in two pre-clinical in vivo tumor models, the potential of fluorescence-guided resection using molecular beacons activated by metalloproteinases, which are frequently upregulated in human oral cancer. In both models there was rapid (beacon activation upon local application, allowing clear fluoresecence imaging in vivo and confirmed by ex vivo fluorescence microscopy and HPLC, with minimal activation in normal oral tissues. Although the tissue penetration was limited using topical application, these findings support further development of this approach towards translation to first-in-human trials. PMID:27231609

  14. Design of a K/Q-Band Beacon Receiver for the Alphasat TDP#5 Experiment

    Morse, Jacquelynne R.

    2014-01-01

    This paper describes the design and performance of a coherent KQ-band (2040 GHz) beacon receiver developed at NASA Glenn Research Center (GRC) that will be installed at the Politecnico di Milano (POLIMI) for use in the Alphasat Technology Demonstration Payload 5 (TDP5) beacon experiment. The goal of this experiment is to characterize rain fade attenuation at 40 GHz to improve the performance of existing statistical rain attenuation models in the Q-band. The ground terminal developed by NASA GRC utilizes an FFT-based frequency estimation receiver capable of characterizing total path attenuation effects due to gaseous absorption, clouds, rain, and scintillation. The receiver system has been characterized in the lab and demonstrates a system dynamic range performance of better than 58 dB at 1 Hz and better than 48 dB at 10 Hz rates.

  15. Nanosecond-level time synchronization of AERA using a beacon reference transmitter and commercial airplanes

    Huege Tim

    2017-01-01

    Full Text Available Radio detection of cosmic-ray air showers requires time synchronization of detectors on a nanosecond level, especially for advanced reconstruction algorithms based on the wavefront curvature and for interferometric analysis approaches. At the Auger Engineering Radio Array, the distributed, autonomous detector stations are time-synchronized via the Global Positioning System which, however, does not provide sufficient timing accuracy. We thus employ a dedicated beacon reference transmitter to correct for eventby-event clock drifts in our offline data analysis. In an independent cross-check of this “beacon correction” using radio pulses emitted by commercial airplanes, we have shown that the combined timing accuracy of the two methods is better than 2 nanoseconds.

  16. Nanosecond-level time synchronization of AERA using a beacon reference transmitter and commercial airplanes

    Huege, Tim

    2017-03-01

    Radio detection of cosmic-ray air showers requires time synchronization of detectors on a nanosecond level, especially for advanced reconstruction algorithms based on the wavefront curvature and for interferometric analysis approaches. At the Auger Engineering Radio Array, the distributed, autonomous detector stations are time-synchronized via the Global Positioning System which, however, does not provide sufficient timing accuracy. We thus employ a dedicated beacon reference transmitter to correct for eventby-event clock drifts in our offline data analysis. In an independent cross-check of this "beacon correction" using radio pulses emitted by commercial airplanes, we have shown that the combined timing accuracy of the two methods is better than 2 nanoseconds.

  17. Detection of Weather Radar Clutter

    Bøvith, Thomas

    2008-01-01

    classification and use a range of different techniques and input data. The first method uses external information from multispectral satellite images to detect clutter. The information in the visual, near-infrared, and infrared parts of the spectrum can be used to distinguish between cloud and cloud-free areas......Weather radars provide valuable information on precipitation in the atmosphere but due to the way radars work, not only precipitation is observed by the weather radar. Weather radar clutter, echoes from non-precipitating targets, occur frequently in the data, resulting in lowered data quality....... Especially in the application of weather radar data in quantitative precipitation estimation and forecasting a high data quality is important. Clutter detection is one of the key components in achieving this goal. This thesis presents three methods for detection of clutter. The methods use supervised...

  18. Increased dose near the skin due to electromagnetic surface beacon transponder.

    Ahn, Kang-Hyun; Manger, Ryan; Halpern, Howard J; Aydogan, Bulent

    2015-05-08

    The purpose of this study was to evaluate the increased dose near the skin from an electromagnetic surface beacon transponder, which is used for localization and tracking organ motion. The bolus effect due to the copper coil surface beacon was evaluated with radiographic film measurements and Monte Carlo simulations. Various beam incidence angles were evaluated for both 6 MV and 18 MV experimentally. We performed simulations using a general-purpose Monte Carlo code MCNPX (Monte Carlo N-Particle) to supplement the experimental data. We modeled the surface beacon geometry using the actual mass of the glass vial and copper coil placed in its L-shaped polyethylene terephthalate tubing casing. Film dosimetry measured factors of 2.2 and 3.0 enhancement in the surface dose for normally incident 6 MV and 18 MV beams, respectively. Although surface dose further increased with incidence angle, the relative contribution from the bolus effect was reduced at the oblique incidence. The enhancement factors were 1.5 and 1.8 for 6 MV and 18 MV, respectively, at an incidence angle of 60°. Monte Carlo simulation confirmed the experimental results and indicated that the epidermal skin dose can reach approximately 50% of the dose at dmax at normal incidence. The overall effect could be acceptable considering the skin dose enhancement is confined to a small area (~ 1 cm2), and can be further reduced by using an opposite beam technique. Further clinical studies are justified in order to study the dosimetric benefit versus possible cosmetic effects of the surface beacon. One such clinical situation would be intact breast radiation therapy, especially large-breasted women.

  19. Surface-attached molecular beacons light the way for DNA sequencing

    Paleček, Emil

    2004-01-01

    Roč. 22, č. 2 (2004), s. 55-58 ISSN 0167-7799 R&D Projects: GA AV ČR IBS5004355; GA ČR GA204/03/0566 Institutional research plan: CEZ:AV0Z5004920 Keywords : molecular beacon * DNA stem-loop structure * DNA sensors Subject RIV: BO - Biophysics Impact factor: 8.606, year: 2004

  20. Beaconing Performance in IEEE 802.11p Vehicular Networks: the Effect of Radio Channel Congestion

    Librino, Francesco; Renda, Maria Elena; Santi, Paolo

    2013-01-01

    In this paper, we study the performance of the beaconing mechanism underlying active safety vehicular applications in presence of different levels of channel congestion. The importance of this study lies in the fact that channel congestion is considered a major factor influencing communication performance in vehicular networks, and that ours is the first investigation of the effects of congestion based on extensive, real-world measurements. The results of our study reveal that congestion has ...

  1. 100 years of radar

    Galati, Gaspare

    2016-01-01

    This book offers fascinating insights into the key technical and scientific developments in the history of radar, from the first patent, taken out by Hülsmeyer in 1904, through to the present day. Landmark events are highlighted and fascinating insights provided into the exceptional people who made possible the progress in the field, including the scientists and technologists who worked independently and under strict secrecy in various countries across the world in the 1930s and the big businessmen who played an important role after World War II. The book encourages multiple levels of reading. The author is a leading radar researcher who is ideally placed to offer a technical/scientific perspective as well as a historical one. He has taken care to structure and write the book in such a way as to appeal to both non-specialists and experts. The book is not sponsored by any company or body, either formally or informally, and is therefore entirely unbiased. The text is enriched by approximately three hundred ima...

  2. Beacon: A three-dimensional structural analysis code for bowing history of fast breeder reactor cores

    Miki, K.

    1979-01-01

    The core elements of an LMFBR are bowed due to radial gradients of both temperature and neutron flux in the core. Since all hexagonal elements are multiply supported by adjacent elements or the restraint system, restraint forces and bending stresses are induced. In turn, these forces and stresses are relaxed by irradiation enhanced creep of the material. The analysis of the core bowing behavior requires a three-dimensional consideration of the mechanical interactions among the core elements, because the core consists of different kinds of elements and of fuel assemblies with various burnup histories. A new computational code BEACON has been developed for analyzing the bowing behavior of an LMFBR's core in three dimensions. To evaluate mechanical interactions among core elements, the code uses the analytical method of the earlier SHADOW code. BEACON analyzes the mechanical interactions in three directions, which form angles of 60 0 with one another. BEACON is applied to the 60 0 sector of a typical LMFBR's core for analyzing the bowing history during one equilibrium cycle. 120 core elements are treated, assuming the boundary condition of rotational symmetry. The application confirms that the code can be an effective tool for parametric studies as well as for detailed structural analysis of LMFBR's core. (orig.)

  3. Magnetic resonance beacon to detect intracellular microRNA during neurogenesis.

    Lee, Jonghwan; Jin, Yeon A; Ko, Hae Young; Lee, Yong Seung; Heo, Hyejung; Cho, Sujeong; Kim, Soonhag

    2015-02-01

    Magnetic resonance imaging (MRI) offers great spatial resolution for viewing deep tissues and anatomy. We developed a self-assembling signal-on magnetic fluorescence nanoparticle to visualize intracellular microRNAs (miRNAs or miRs) during neurogenesis using MRI. The self-assembling nanoparticle (miR124a MR beacon) was aggregated by the incubation of three different oligonucleotides: a 3' adaptor, a 5' adaptor, and a linker containing miR124a-binding sequences. The T2-weighted magnetic resonance (MR) signal of the self-assembled nanoparticle was quenched when miR124a was absent from test tubes or was minimally expressed in cells and tissues. When miR124a was present in test tubes or highly expressed in vitro and in vivo during P19 cell neurogenesis, it hybridized with the miR124a MR beacon, causing the linker to detach, resulting in increased signal-on MRI intensity. This MR beacon can be used as a new imaging probe to monitor the miRNA-mediated regulation of cellular processes. Copyright © 2014 Elsevier Ltd. All rights reserved.

  4. A Microfluidic Love-Wave Biosensing Device for PSA Detection Based on an Aptamer Beacon Probe.

    Zhang, Feng; Li, Shuangming; Cao, Kang; Wang, Pengjuan; Su, Yan; Zhu, Xinhua; Wan, Ying

    2015-06-11

    A label-free and selective aptamer beacon-based Love-wave biosensing device was developed for prostate specific antigen (PSA) detection. The device consists of the following parts: LiTaO3 substrate with SiO2 film as wave guide layer, two set of inter-digital transducers (IDT), gold film for immobilization of the biorecongniton layer and a polydimethylsiloxane (PDMS) microfluidic channels. DNA aptamer, or "artificial antibody", was used as the specific biorecognition probe for PSA capture. Some nucleotides were added to the 3'-end of the aptamer to form a duplex with the 3'-end, turning the aptamer into an aptamer-beacon. Taking advantage of the selective target-induced assembly changes arising from the "aptamer beacon", highly selective and specific detection of PSA was achieved. Furthermore, PDMS microfluidic channels were designed and fabricated to realize automated quantitative sample injection. After optimization of the experimental conditions, the established device showed good performance for PSA detection between 10 ng/mL to 1 μg/mL, with a detection limit of 10 ng/mL. The proposed sensor might be a promising alternative for point of care diagnostics.

  5. Sparse Localization with a Mobile Beacon Based on LU Decomposition in Wireless Sensor Networks

    Chunhui Zhao

    2015-09-01

    Full Text Available Node localization is the core in wireless sensor network. It can be solved by powerful beacons, which are equipped with global positioning system devices to know their location information. In this article, we present a novel sparse localization approach with a mobile beacon based on LU decomposition. Our scheme firstly translates node localization problem into a 1-sparse vector recovery problem by establishing sparse localization model. Then, LU decomposition pre-processing is adopted to solve the problem that measurement matrix does not meet the re¬stricted isometry property. Later, the 1-sparse vector can be exactly recovered by compressive sensing. Finally, as the 1-sparse vector is approximate sparse, weighted Cen¬troid scheme is introduced to accurately locate the node. Simulation and analysis show that our scheme has better localization performance and lower requirement for the mobile beacon than MAP+GC, MAP-M, and MAP-MN schemes. In addition, the obstacles and DOI have little effect on the novel scheme, and it has great localization performance under low SNR, thus, the scheme proposed is robust.

  6. POLCAL - POLARIMETRIC RADAR CALIBRATION

    Vanzyl, J.

    1994-01-01

    Calibration of polarimetric radar systems is a field of research in which great progress has been made over the last few years. POLCAL (Polarimetric Radar Calibration) is a software tool intended to assist in the calibration of Synthetic Aperture Radar (SAR) systems. In particular, POLCAL calibrates Stokes matrix format data produced as the standard product by the NASA/Jet Propulsion Laboratory (JPL) airborne imaging synthetic aperture radar (AIRSAR). POLCAL was designed to be used in conjunction with data collected by the NASA/JPL AIRSAR system. AIRSAR is a multifrequency (6 cm, 24 cm, and 68 cm wavelength), fully polarimetric SAR system which produces 12 x 12 km imagery at 10 m resolution. AIRSTAR was designed as a testbed for NASA's Spaceborne Imaging Radar program. While the images produced after 1991 are thought to be calibrated (phase calibrated, cross-talk removed, channel imbalance removed, and absolutely calibrated), POLCAL can and should still be used to check the accuracy of the calibration and to correct it if necessary. Version 4.0 of POLCAL is an upgrade of POLCAL version 2.0 released to AIRSAR investigators in June, 1990. New options in version 4.0 include automatic absolute calibration of 89/90 data, distributed target analysis, calibration of nearby scenes with calibration parameters from a scene with corner reflectors, altitude or roll angle corrections, and calibration of errors introduced by known topography. Many sources of error can lead to false conclusions about the nature of scatterers on the surface. Errors in the phase relationship between polarization channels result in incorrect synthesis of polarization states. Cross-talk, caused by imperfections in the radar antenna itself, can also lead to error. POLCAL reduces cross-talk and corrects phase calibration without the use of ground calibration equipment. Removing the antenna patterns during SAR processing also forms a very important part of the calibration of SAR data. Errors in the

  7. Estimation of High-Frequency Earth-Space Radio Wave Signals via Ground-Based Polarimetric Radar Observations

    Bolen, Steve; Chandrasekar, V.

    2002-01-01

    Expanding human presence in space, and enabling the commercialization of this frontier, is part of the strategic goals for NASA's Human Exploration and Development of Space (HEDS) enterprise. Future near-Earth and planetary missions will support the use of high-frequency Earth-space communication systems. Additionally, increased commercial demand on low-frequency Earth-space links in the S- and C-band spectra have led to increased interest in the use of higher frequencies in regions like Ku and Ka-band. Attenuation of high-frequency signals, due to a precipitating medium, can be quite severe and can cause considerable disruptions in a communications link that traverses such a medium. Previously, ground radar measurements were made along the Earth-space path and compared to satellite beacon data that was transmitted to a ground station. In this paper, quantitative estimation of the attenuation along the propagation path is made via inter-comparisons of radar data taken from the Tropical Rainfall Measuring Mission (TRMM) Precipitation Radar (PR) and ground-based polarimetric radar observations. Theoretical relationships between the expected specific attenuation (k) of spaceborne measurements with ground-based measurements of reflectivity (Zh) and differential propagation phase shift (Kdp) are developed for various hydrometeors that could be present along the propagation path, which are used to estimate the two-way path-integrated attenuation (PIA) on the PR return echo. Resolution volume matching and alignment of the radar systems is performed, and a direct comparison of PR return echo with ground radar attenuation estimates is made directly on a beam-by-beam basis. The technique is validated using data collected from the TExas and Florida UNderflights (TEFLUN-B) experiment and the TRMM large Biosphere-Atmosphere experiment in Amazonia (LBA) campaign. Attenuation estimation derived from this method can be used for strategiC planning of communication systems for

  8. Interception of LPI radar signals

    Lee, Jim P.

    1991-11-01

    Most current radars are designed to transmit short duration pulses with relatively high peak power. These radars can be detected easily by the use of relatively modest EW intercept receivers. Three radar functions (search, anti-ship missile (ASM) seeker, and navigation) are examined to evaluate the effectiveness of potential low probability of intercept (LPI) techniques, such as waveform coding, antenna profile control, and power management that a radar may employ against current Electronic Warfare (EW) receivers. The general conclusion is that it is possible to design a LPI radar which is effective against current intercept EW receivers. LPI operation is most easily achieved at close ranges and against a target with a large radar cross section. The general system sensitivity requirement for the detection of current and projected LPI radars is found to be on the order of -100 dBmi which cannot be met by current EW receivers. Finally, three potential LPI receiver architectures, using channelized, superhet, and acousto-optic receivers with narrow RF and video bandwidths are discussed. They have shown some potential in terms of providing the sensitivity and capability in an environment where both conventional and LPI signals are present.

  9. Radar signal analysis and processing using Matlab

    Mahafza, Bassem R

    2008-01-01

    Offering radar-related software for the analysis and design of radar waveform and signal processing, this book provides comprehensive coverage of radar signals and signal processing techniques and algorithms. It contains numerous graphical plots, common radar-related functions, table format outputs, and end-of-chapter problems. The complete set of MATLAB[registered] functions and routines are available for download online.

  10. The use of radar for bathymetry assessment

    Aardoom, J.H.; Greidanus, H.S.F.

    1998-01-01

    The bottom topography in shallow seas can be observed by air- and spaceborne imaging radar. Bathymetric information derived from radar data is limited in accuracy, but radar has a good spatial coverage. The accuracy can be increased by assimilating the radar imagery into existing or insitu gathered

  11. Radar observations of asteroids

    Ostro, S.J.

    1989-01-01

    This paper describes echoes from 33 main-belt asteroids (MBAs) and 19 near-Earth asteroids (NEAs) have provided a wealth of new information about these objects such as sizes, shapes, spin vectors, and such surface characteristics as decimeter-scale morphology, topographic relief, regolith porosity and metal concentrations. On average, small NEAs are much rougher at decimeter scales than MBAs, comets or terrestrial planets. Some of the largest MBAs (e.g., 1 Ceres and 2 Pallas ) are smoother than the moon at decimeter scales but much rougher than the Moon at some much larger scale. There is at least a five-fold variation in the radar albedos of MBAs, implying substantial variations in the surface porosities or metal concentrations of these objects. The highest MBA albedo estimate, for 16 Psyche, is consistent with a metal concentration near unity and lunar porosities

  12. Under the Radar

    Goss, WM

    2010-01-01

    This is the biography of Ruby Payne-Scott (1912 to 1981). As the first female radio astronomer (and one of the first people in the world to consider radio astronomy), she made classic contributions to solar radio physics. She also played a major role in the design of the Australian government's Council for Scientific and Industrial Research radars, which were in turn of vital importance in the Southwest Pacific Theatre in World War II and were used by Australian, US and New Zealand personnel. From a sociological perspective, her career also offers many examples of the perils of being a female academic in the first half of the 20th century. Written in an engaging style and complemented by many historical photographs this book gives a fascinating insight into the beginning of radio astronomy and the role of a pioneering woman in astronomy.

  13. Material integrity verification radar

    Koppenjan, S.K.

    1999-01-01

    The International Atomic Energy Agency (IAEA) has the need for verification of 'as-built' spent fuel-dry storage containers and other concrete structures. The IAEA has tasked the Special Technologies Laboratory (STL) to fabricate, test, and deploy a stepped-frequency Material Integrity Verification Radar (MIVR) system to nondestructively verify the internal construction of these containers. The MIVR system is based on previously deployed high-frequency, ground penetrating radar (GPR) systems that have been developed by STL for the U.S. Department of Energy (DOE). Whereas GPR technology utilizes microwave radio frequency energy to create subsurface images, MTVR is a variation for which the medium is concrete instead of soil. The purpose is to nondestructively verify the placement of concrete-reinforcing materials, pipes, inner liners, and other attributes of the internal construction. The MIVR system underwent an initial field test on CANDU reactor spent fuel storage canisters at Atomic Energy of Canada Limited (AECL), Chalk River Laboratories, Ontario, Canada, in October 1995. A second field test at the Embalse Nuclear Power Plant in Embalse, Argentina, was completed in May 1996. The DOE GPR also was demonstrated at the site. Data collection and analysis were performed for the Argentine National Board of Nuclear Regulation (ENREN). IAEA and the Brazilian-Argentine Agency for the Control and Accounting of Nuclear Material (ABACC) personnel were present as observers during the test. Reinforcing materials were evident in the color, two-dimensional images produced by the MIVR system. A continuous pattern of reinforcing bars was evident and accurate estimates on the spacing, depth, and size were made. The potential uses for safeguard applications were jointly discussed. The MIVR system, as successfully demonstrated in the two field tests, can be used as a design verification tool for IAEA safeguards. A deployment of MIVR for Design Information Questionnaire (DIQ

  14. Air and spaceborne radar systems an introduction

    Lacomme, Philippe; Hardange, Jean-Philippe; Normant, Eric

    2001-01-01

    A practical tool on radar systems that will be of major help to technicians, student engineers and engineers working in industry and in radar research and development. The many users of radar as well as systems engineers and designers will also find it highly useful. Also of interest to pilots and flight engineers and military command personnel and military contractors. """"This introduction to the field of radar is intended for actual users of radar. It focuses on the history, main principles, functions, modes, properties and specific nature of modern airborne radar. The book examines radar's

  15. Signal processing in noise waveform radar

    Kulpa, Krzysztof

    2013-01-01

    This book is devoted to the emerging technology of noise waveform radar and its signal processing aspects. It is a new kind of radar, which use noise-like waveform to illuminate the target. The book includes an introduction to basic radar theory, starting from classical pulse radar, signal compression, and wave radar. The book then discusses the properties, difficulties and potential of noise radar systems, primarily for low-power and short-range civil applications. The contribution of modern signal processing techniques to making noise radar practical are emphasized, and application examples

  16. Introduction to radar target recognition

    Tait, P

    2006-01-01

    This new text provides an overview of the radar target recognition process and covers the key techniques being developed for operational systems. It is based on the fundamental scientific principles of high resolution radar, and explains how the techniques can be used in real systems, taking into account the characteristics of practical radar system designs and component limitations. It also addresses operational aspects, such as how high resolution modes would fit in with other functions such as detection and tracking. Mathematics is kept to a minimum and the complex techniques and issues are

  17. Radar spectrum opportunities for cognitive communications transmission

    Wang, L; McGeehan, JP; Williams, C; Doufexi, A

    2008-01-01

    In relation to opportunistic access to radar spectrum, the impact of the radar on a communication system is investigated in this paper. This paper illustrates that by exploring the spatial and temporal opportunities in the radar spectrum and therefore improving the tolerance level to radar interference, a substantial increase on the throughput of a communication system is possible. Results are presented regarding the impact of swept radars on a WiMAX system. The results show the impact of SIR...

  18. Solid-state radar switchboard

    Thiebaud, P.; Cross, D. C.

    1980-07-01

    A new solid-state radar switchboard equipped with 16 input ports which will output data to 16 displays is presented. Each of the ports will handle a single two-dimensional radar input, or three ports will accommodate a three-dimensional radar input. A video switch card of the switchboard is used to switch all signals, with the exception of the IFF-mode-control lines. Each card accepts inputs from up to 16 sources and can pass a signal with bandwidth greater than 20 MHz to the display assigned to that card. The synchro amplifier of current systems has been eliminated and in the new design each PPI receives radar data via a single coaxial cable. This significant reduction in cabling is achieved by adding a serial-to-parallel interface and a digital-to-synchro converter located at the PPI.

  19. SMAP RADAR Calibration and Validation

    West, R. D.; Jaruwatanadilok, S.; Chaubel, M. J.; Spencer, M.; Chan, S. F.; Chen, C. W.; Fore, A.

    2015-12-01

    The Soil Moisture Active Passive (SMAP) mission launched on Jan 31, 2015. The mission employs L-band radar and radiometer measurements to estimate soil moisture with 4% volumetric accuracy at a resolution of 10 km, and freeze-thaw state at a resolution of 1-3 km. Immediately following launch, there was a three month instrument checkout period, followed by six months of level 1 (L1) calibration and validation. In this presentation, we will discuss the calibration and validation activities and results for the L1 radar data. Early SMAP radar data were used to check commanded timing parameters, and to work out issues in the low- and high-resolution radar processors. From April 3-13 the radar collected receive only mode data to conduct a survey of RFI sources. Analysis of the RFI environment led to a preferred operating frequency. The RFI survey data were also used to validate noise subtraction and scaling operations in the radar processors. Normal radar operations resumed on April 13. All radar data were examined closely for image quality and calibration issues which led to improvements in the radar data products for the beta release at the end of July. Radar data were used to determine and correct for small biases in the reported spacecraft attitude. Geo-location was validated against coastline positions and the known positions of corner reflectors. Residual errors at the time of the beta release are about 350 m. Intra-swath biases in the high-resolution backscatter images are reduced to less than 0.3 dB for all polarizations. Radiometric cross-calibration with Aquarius was performed using areas of the Amazon rain forest. Cross-calibration was also examined using ocean data from the low-resolution processor and comparing with the Aquarius wind model function. Using all a-priori calibration constants provided good results with co-polarized measurements matching to better than 1 dB, and cross-polarized measurements matching to about 1 dB in the beta release. During the

  20. The NASA Polarimetric Radar (NPOL)

    Petersen, Walter A.; Wolff, David B.

    2013-01-01

    Characteristics of the NASA NPOL S-band dual-polarimetric radar are presented including its operating characteristics, field configuration, scanning capabilities and calibration approaches. Examples of precipitation science data collections conducted using various scan types, and associated products, are presented for different convective system types and previous field campaign deployments. Finally, the NASA NPOL radar location is depicted in its home base configuration within the greater Wallops Flight Facility precipitation research array supporting NASA Global Precipitation Measurement Mission ground validation.

  1. Surveillance technology for HIV-1 subtype C in Ethiopia: an env-based NASBA molecular beacon assay to discriminate between subcluster C and C'

    Ayele, Workenesh; Baar, Michel P. de; Goudsmit, Jaap; Kliphuis, Aletta; Tilahun, Tesfaye; Dorigo-Zetsma, Wendelien; Wolday, Dawit; Abebe, Almaz; Mengistu, Yohannes; Pollakis, Georgios

    2005-01-01

    Forty-nine samples with known C2V3 sequences were used for the evaluation of an env-based molecular beacon assay to distinguish between the two genetic subclusters C and C' which characterize the HIV-1 epidemic in Ethiopia. Two subcluster C and two subcluster C' beacons targeting two different loci

  2. Molecular beacon probes-base multiplex NASBA Real-time for detection of HIV-1 and HCV.

    Mohammadi-Yeganeh, S; Paryan, M; Mirab Samiee, S; Kia, V; Rezvan, H

    2012-06-01

    Developed in 1991, nucleic acid sequence-based amplification (NASBA) has been introduced as a rapid molecular diagnostic technique, where it has been shown to give quicker results than PCR, and it can also be more sensitive. This paper describes the development of a molecular beacon-based multiplex NASBA assay for simultaneous detection of HIV-1 and HCV in plasma samples. A well-conserved region in the HIV-1 pol gene and 5'-NCR of HCV genome were used for primers and molecular beacon design. The performance features of HCV/HIV-1 multiplex NASBA assay including analytical sensitivity and specificity, clinical sensitivity and clinical specificity were evaluated. The analysis of scalar concentrations of the samples indicated that the limit of quantification of the assay was beacon probes detected all HCV genotypes and all major variants of HIV-1. This method may represent a relatively inexpensive isothermal method for detection of HIV-1/HCV co-infection in monitoring of patients.

  3. Phase calibration approaches for radar interferometry and imaging configurations: equatorial spread F results

    J. L. Chau

    2008-08-01

    Full Text Available In recent years, more and more radar systems with multiple-receiver antennas are being used to study the atmospheric and ionospheric irregularities with either interferometric and/or imaging configurations. In such systems, one of the major challenges is to know the phase offsets between the different receiver channels. Such phases are intrinsic to the system and are due to different cable lengths, filters, attenuators, amplifiers, antenna impedance, etc. Moreover, such phases change as function of time, on different time scales, depending on the specific installation. In this work, we present three approaches using natural targets (radio stars, meteor-head and meteor trail echoes that allow either an absolute or relative phase calibration. In addition, we present the results of using an artificial source (radio beacon for a continuous calibration that complements the previous approaches. These approaches are robust and good alternatives to other approaches, e.g. self-calibration techniques using known data features, or for multiple-receiver configurations constantly changing their receiving elements. In order to show the good performance of the proposed phase calibration techniques, we present new radar imaging results of equatorial spread F (ESF irregularities. Finally we introduce a new way to represent range-time intensity (RTI maps color coded with the Doppler information. Such modified map allows the identification and interpretation of geophysical phenomena, previously hidden in conventional RTI maps, e.g. the time and altitude of occurrence of ESF irregularities pinching off from the bottomside and their respective Doppler velocity.

  4. Creating a Connected Community: Lessons Learned from the Western New York Beacon Community

    Maloney, Nancy; Heider, Arvela R.; Rockwood, Amy; Singh, Ranjit

    2014-01-01

    Introduction: Secure exchange of clinical data among providers has the potential to improve quality, safety, efficiency, and reduce duplication. Many communities are experiencing challenges in building effective health information exchanges (HIEs). Previous studies have focused on financial and technical issues regarding HIE development. This paper describes the Western New York (WNY) HIE growth and lessons learned about accelerating progress to become a highly connected community. Methods: HEALTHeLINK, with funding from the Office of the National Coordinator for Health Information Technology (ONC) under the Beacon Community Program, expanded HIE usage in eight counties. The communitywide transformation process used three main drivers: (1) a communitywide Electronic Health Record (EHR) adoption program; (2) clinical transformation partners; and (3) HIE outreach and infrastructure development. Results: ONC Beacon Community funding allowed WNY to achieve a new level in the use of interoperable HIE. Electronic delivery of results into the EHR expanded from 23 practices in 2010 to 222 practices in 2013, a tenfold increase. There were more than 12.5 million results delivered electronically (HL7 messages) to 222 practices’ EHRs via the HIE in 2013. Use of a secure portal and Virtual Health Record (VHR) to access reports (those not delivered directly to the EHR) also increased significantly, from 13,344 report views in 2010 to over 600,000 in 2013. Discussion and Conclusion: The WNY Beacon successfully expanded the sharing of clinical information among different sources of data and providers, creating a highly connected community to improve the quality and continuity of care. Technical, organizational, and community lessons described in this paper should prove beneficial to others as they pursue efforts to create connected communities. PMID:25848618

  5. Making it local: Beacon Communities use health information technology to optimize care management.

    Allen, Amy; Des Jardins, Terrisca R; Heider, Arvela; Kanger, Chatrian R; Lobach, David F; McWilliams, Lee; Polello, Jennifer M; Rein, Alison L; Schachter, Abigail A; Singh, Ranjit; Sorondo, Barbara; Tulikangas, Megan C; Turske, Scott A

    2014-06-01

    Care management aims to provide cost-effective, coordinated, non-duplicative care to improve care quality, population health, and reduce costs. The 17 communities receiving funding from the Office of the National Coordinator for Health Information Technology through the Beacon Community Cooperative Agreement Program are leaders in building and strengthening their health information technology (health IT) infrastructure to provide more effective and efficient care management. This article profiles 6 Beacon Communities' health IT-enabled care management programs, highlighting the influence of local context on program strategy and design, and describing challenges, lessons learned, and policy implications for care delivery and payment reform. The unique needs (eg, disease burden, demographics), community partnerships, and existing resources and infrastructure all exerted significant influence on the overall priorities and design of each community's care management program. Though each Beacon Community needed to engage in a similar set of care management tasks--including patient identification, stratification, and prioritization; intervention; patient engagement; and evaluation--the contextual factors helped shape the specific strategies and tools used to carry out these tasks and achieve their objectives. Although providers across the country are striving to deliver standardized, high-quality care, the diverse contexts in which this care is delivered significantly influence the priorities, strategies, and design of community-based care management interventions. Gaps and challenges in implementing effective community-based care management programs include: optimizing allocation of care management services; lack of available technology tailored to care management needs; lack of standards and interoperability; integrating care management into care settings; evaluating impact; and funding and sustainability.

  6. A distance-dependent metal-enhanced fluorescence sensing platform based on molecular beacon design.

    Zhou, Zhenpeng; Huang, Hongduan; Chen, Yang; Liu, Feng; Huang, Cheng Zhi; Li, Na

    2014-02-15

    A new metal-enhanced fluorescence (MEF) based platform was developed on the basis of distance-dependent fluorescence quenching-enhancement effect, which combined the easiness of Ag-thiol chemistry with the MEF property of noble-metal structures as well as the molecular beacon design. For the given sized AgNPs, the fluorescence enhancement factor was found to increase with a d(6) dependency in agreement with fluorescence resonance energy transfer mechanism at shorter distance and decrease with a d(-3) dependency in agreement with plasmonic enhancement mechanism at longer distance between the fluorophore and the AgNP surface. As a proof of concept, the platform was demonstrated by a sensitive detection of mercuric ions, using thymine-containing molecular beacon to tune silver nanoparticle (AgNP)-enhanced fluorescence. Mercuric ions were detected via formation of a thymine-mercuric-thymine structure to open the hairpin, facilitating fluorescence recovery and AgNP enhancement to yield a limit of detection of 1 nM, which is well below the U.S. Environmental Protection Agency regulation of the Maximum Contaminant Level Goal (10nM) in drinking water. Since the AgNP functioned as not only a quencher to reduce the reagent blank signal but also an enhancement substrate to increase fluorescence of the open hairpin when target mercuric ions were present, the quenching-enhancement strategy can greatly improve the detection sensitivity and can in principle be a universal approach for various targets when combined with molecular beacon design. © 2013 Elsevier B.V. All rights reserved.

  7. Performance of the NASA Beacon Receiver for the Alphasat Aldo Paraboni TDP5 Propagation Experiment

    Nessel, James; Morse, Jacquelynne; Zemba, Michael; Riva, Carlo; Luini, Lorenzo

    2015-01-01

    NASA Glenn Research Center (GRC) and the Politecnico di Milano (POLIMI) have initiated a joint propagation campaign within the framework of the Alphasat propagation experiment to characterize rain attenuation, scintillation, and gaseous absorption effects of the atmosphere in the 40 gigahertz band. NASA GRC has developed and installed a K/Q-band (20/40 gigahertz) beacon receiver at the POLIMI campus in Milan, Italy, which receives the 20/40 gigahertz signals broadcast from the Alphasat Aldo Paraboni Technology Demonstration Payload (TDP) no. 5 beacon payload. The primary goal of these measurements is to develop a physical model to improve predictions of communications systems performance within the Q-band. Herein, we describe the design and preliminary performance of the NASA propagation terminal, which has been installed and operating in Milan since June 2014. The receiver is based upon a validated Fast Fourier Transform (FFT) I/Q digital design approach utilized in other operational NASA propagation terminals, but has been modified to employ power measurement via a frequency estimation technique and to coherently track and measure the amplitude of the 20/40 gigahertz beacon signals. The system consists of a 1.2-meter K-band and a 0.6-meter Q-band Cassegrain reflector employing synchronous open-loop tracking to track the inclined orbit of the Alphasat satellite. An 8 hertz sampling rate is implemented to characterize scintillation effects, with a 1-hertz measurement bandwidth dynamic range of 45 decibels. A weather station with an optical disdrometer is also installed to characterize rain drop size distribution for correlation with physical based models.

  8. Preliminary Results of the NASA Beacon Receiver for Alphasat Aldo Paraboni TDP5 Propagation Experiment

    Nessel, James; Morse, Jacquelynne; Zemba, Michael; Riva, Carlo; Luini, Lorenzo

    2014-01-01

    NASA Glenn Research Center (GRC) and the Politecnico di Milano (POLIMI) have initiated a joint propagation campaign within the framework of the Alphasat propagation experiment to characterize rain attenuation, scintillation, and gaseous absorption effects of the atmosphere in the 40 GHz band. NASA GRC has developed and installed a K/Q-band (20/40 GHz) beacon receiver at the POLIMI campus in Milan, Italy, which receives the 20/40 GHz signals broadcast from the Alphasat Aldo Paraboni TDP#5 beacon payload. The primary goal of these measurements is to develop a physical model to improve predictions of communications systems performance within the Q-band. Herein, we describe the design and preliminary performance of the NASA propagation terminal, which has been installed and operating in Milan since May 2014. The receiver is based upon a validated Fast Fourier Transform (FFT) I/Q digital design approach utilized in other operational NASA propagation terminals, but has been modified to employ power measurement via a frequency estimation technique and to coherently track and measure the amplitude of the 20/40 GHz beacon signals. The system consists of a 1.2-m K-band and a 0.6-m Qband Cassegrain reflector employing synchronous open-loop tracking to track the inclined orbit of the Alphasat satellite. An 8 Hz sampling rate is implemented to characterize scintillation effects, with a 1-Hz measurement bandwidth dynamic range of 45 dB. A weather station with an optical disdrometer is also installed to characterize rain drop size distribution for correlation with physical based models.

  9. The use of low frequency HF beacons to derive layer shape

    Heron, M.L.; Davies, K.

    1978-01-01

    The ATS-6 with its coherent multifrequency channels and various calibrations has brought the technology of beacon experiments to the point where the experimental accuracy exceeds that of some of the approximations used to derive total electron content. For example, the magnetic field term in the Faraday rotation experiment used to be given a mean value corresponding to about 50 km above the F layer peak. Another quantity that depends on profile shape is also available with present experiment, namely the refraction or second order term for carrier phase, modulation phase, or Faraday rotation. Some theoretical and experimental results are presented on these problems

  10. Developing children’s palliative care in Africa through beacon centres: lessons learnt

    2013-01-01

    Much progress has been made in the provision of palliative care across sub-Saharan Africa, however much still remains to be done, particularly in the area of children’s palliative care (CPC). The Beacon Centres programme was set up in 2009, aimed at improving access to CPC in South Africa, Uganda and Tanzania through more and better-trained health professionals and CPC clinical services of a high standard. Having identified sites in each country to develop into CPC Beacon Centres, Navigators were identified who would be the ‘champions’ for CPC in those sites and lead a programme of training, mentorship and support. Five navigators (2 in Uganda and Tanzania and 1 in South Africa) were trained between September and December 2009. Following this they undertook CPC needs assessments at the 3 centres and set up and delivered a six-month CPC training programme, providing mentorship and support to students to enable them to integrate CPC into their workplaces. To date, 188 participants have commenced the six-month course, with 80 having completed it. CPC has been integrated into the activities of the centres and a CPC virtual resource centre set up in South Africa. The achievements from the Beacon project have been great and the work of the navigators immense, but as in all projects it has not been without its challenges. Lessons learnt include issues around: the focus of the project; the length and nature of the training; assessment; accreditation; the choice of navigators; mentoring; administrative support; co-ordination; the choice of project sites; and the integration of CPC into services. The need for CPC is not going to go away and it is therefore important that models of scaling-up are found that are not only practical, feasible, affordable and sustainable, but that focus on the outcome of improved CPC for all those who need it. It is hoped that the lessons shared from the Beacon Project will help in developing and implementing such models. PMID:23419095

  11. Controlling the signal: Practical privacy protection of genomic data sharing through Beacon services.

    Wan, Zhiyu; Vorobeychik, Yevgeniy; Kantarcioglu, Murat; Malin, Bradley

    2017-07-26

    Genomic data is increasingly collected by a wide array of organizations. As such, there is a growing demand to make summary information about such collections available more widely. However, over the past decade, a series of investigations have shown that attacks, rooted in statistical inference methods, can be applied to discern the presence of a known individual's DNA sequence in the pool of subjects. Recently, it was shown that the Beacon Project of the Global Alliance for Genomics and Health, a web service for querying about the presence (or absence) of a specific allele, was vulnerable. The Integrating Data for Analysis, Anonymization, and Sharing (iDASH) Center modeled a track in their third Privacy Protection Challenge on how to mitigate the Beacon vulnerability. We developed the winning solution for this track. This paper describes our computational method to optimize the tradeoff between the utility and the privacy of the Beacon service. We generalize the genomic data sharing problem beyond that which was introduced in the iDASH Challenge to be more representative of real world scenarios to allow for a more comprehensive evaluation. We then conduct a sensitivity analysis of our method with respect to several state-of-the-art methods using a dataset of 400,000 positions in Chromosome 10 for 500 individuals from Phase 3 of the 1000 Genomes Project. All methods are evaluated for utility, privacy and efficiency. Our method achieves better performance than all state-of-the-art methods, irrespective of how key factors (e.g., the allele frequency in the population, the size of the pool and utility weights) change from the original parameters of the problem. We further illustrate that it is possible for our method to exhibit subpar performance under special cases of allele query sequences. However, we show our method can be extended to address this issue when the query sequence is fixed and known a priori to the data custodian, so that they may plan stage their

  12. The Southeastern Minnesota Beacon Project for Community-driven Health Information Technology: Origins, Achievements, and Legacy.

    Chute, Christopher G; Hart, Lacey A; Alexander, Alex K; Jensen, Daniel W

    2014-01-01

    The Southeastern (SE) Minnesota Beacon organized all the health care providers, county public health organizations, and school districts in the deployment and integration of health information exchange (HIE) and targeted health communication around childhood asthma and diabetes. The community cooperated to establish a clinical data repository for all residents in the 11-county region. Through this community of practice approach that involved traditional and nontraditional providers, the SE Minnesota Beacon was able to realize unique applications of this technology. This manuscript overviews the associated organization and infrastructure of this community collaboration. The Office of the National Coordinator for Health Information Technology (ONC), as part of the American Recovery and Reinvestment Act of 2009 (ARRA) stimulus, established 17 projects throughout the United States targeting the introduction and meaningful use of health information technology (HIT). These 17 communities were intended to serve as an example of what could be accomplished. The SE Minnesota Beacon is one of these communities. The community ultimately opted for peer-to-peer HIE, using Nationwide Health Information Network (NwHIN) Connect software. The clinical data repository was established using the infrastructure developed by the Regenstrief Institute, which operated as a trusted third party. As an extension to HIE, the consortium of county public health departments created a patient data portal for use by school nurses and parents. Childhood asthma was addressed by creating, exchanging, and maintaining an "asthma action plan" for each affected child, shared throughout the community, including through the patient portal. Diabetes management introduced patient treatment decision tools and patient quality of life measures, facilitating care. Influenza vaccination was enhanced by large-scale community reporting in partnership with the state vaccination registry. The methodology and

  13. Enzymatic Amplification of DNA/RNA Hybrid Molecular Beacon Signaling in Nucleic Acid Detection

    Jacroux, Thomas; Rieck, Daniel C.; Cui, Rong; Ouyang, Yexin; Dong, Wen-Ji

    2012-01-01

    A rapid assay operable under isothermal or non-isothermal conditions is described wherein the sensitivity of a typical molecular beacon (MB) system is improved by utilizing thermostable RNase H to enzymatically cleave an MB comprised of a DNA stem and RNA loop (R/D-MB). Upon hybridization of the R/D-MB to target DNA, there was a modest increase in fluorescence intensity (~5.7x above background) due to an opening of the probe and concomitant reduction in the Förster resonance energy transfer e...

  14. In situ exposure to non-directional beacons for air traffic control.

    Joseph, Wout; Goeminne, Francis; Vermeeren, Günter; Verloock, Leen; Martens, Luc

    2012-04-01

    In situ electromagnetic field exposure of workers and the general public due to non-directional beacons (NDB) for air traffic control is assessed and characterized. For occupational exposure, the maximal measured electric field value is 881.6 V/m and the maximal magnetic field value is 9.1 A/m. The maximum electric fields exceed the International Commission on Non-Ionizing Radiation Protection (ICNIRP) reference levels at all seven NDB sites, and the magnetic fields at two of the seven NDB sites (occupational exposure). Recommendations and compliance distances for workers and the general public are provided. © 2012 Wiley Periodicals, Inc.

  15. Observability analysis of 2D single-beacon navigation in the presence of constant currents for two classes of maneuvers

    Crasta, N.; Bayat, M.; Aguiar, A.P.; Pascoal, A.M.

    . In particular, xc = 0 represents a circular motion about the beacon with radius v ω−1. The following result characterizes set of indistinguishable states for the system (5.1)-(5.2) subject to input class Ucir. Proposition 5.6. Consider the system (5...) = npi + 0.5 (−1)n pi, n ∈ Z. Notice also that under this condition the motion is a circular motion around the beacon. The following corollary follows from propositions 5.3 and 5.6. Corollary 5.8. Consider x0 ∈ M. Then (4.1)-(4.2) is observable...

  16. Borehole radar diffraction tomography

    Cho, Seong Jun; Kim, Jung Ho; Yi, Myeong Jong; Chung, Seung Hwan; Lee, Hee Il [Korea Institute of Geology Mining and Materials, Taejon (Korea, Republic of)

    1997-12-01

    Tomography is widely used as imaging method for determining subsurface structure. Among the reconstruction algorithms for tomographic imaging, travel time tomography is almost applied to imaging subsurface. But isolated small body comparable with the wavelength could not be well recognized by travel time tomography. Other tomographic method are need to improve the imaging process. In the study of this year, diffraction tomography was investigated. The theory for diffraction tomography is based on the 1st-order Born approximation. Multisource holography, which is similar to Kirchihoff migration, is compared with diffraction tomography. To improve 1st-order Born diffraction tomography, two kinds of filter designed from multisource holography and 2-D green function, respectively, applied on the reconstructed image. The algorithm was tested for the numerical modeling data of which algorithm consists of the analytic computation of radar signal in transmitter and receiver regions and 2-D FDM scheme for the propagation of electromagnetic waves in media. The air-filled cavity model to show a typical diffraction pattern was applied to diffraction tomography imaging, and the result shows accurate location and area of cavity. But the calculated object function is not well matched the real object function, because the air-filled cavity model is not satisfied week scattered inhomogeneity for 1st born approximation, and the error term is included in estimating source wavelet from received signals. In spite of the object function error, the diffraction tomography assist for interpretation of subsurface as if conducted with travel time tomography. And the fracture model was tested, 1st born diffraction tomographic image is poor because of limited view angle coverage and violation of week scatter assumption, but the filtered image resolve the fracture somewhat better. The tested diffraction tomography image confirms effectiveness of filter for enhancing resolution. (author). 14

  17. Radar rainfall image repair techniques

    Stephen M. Wesson

    2004-01-01

    Full Text Available There are various quality problems associated with radar rainfall data viewed in images that include ground clutter, beam blocking and anomalous propagation, to name a few. To obtain the best rainfall estimate possible, techniques for removing ground clutter (non-meteorological echoes that influence radar data quality on 2-D radar rainfall image data sets are presented here. These techniques concentrate on repairing the images in both a computationally fast and accurate manner, and are nearest neighbour techniques of two sub-types: Individual Target and Border Tracing. The contaminated data is estimated through Kriging, considered the optimal technique for the spatial interpolation of Gaussian data, where the 'screening effect' that occurs with the Kriging weighting distribution around target points is exploited to ensure computational efficiency. Matrix rank reduction techniques in combination with Singular Value Decomposition (SVD are also suggested for finding an efficient solution to the Kriging Equations which can cope with near singular systems. Rainfall estimation at ground level from radar rainfall volume scan data is of interest and importance in earth bound applications such as hydrology and agriculture. As an extension of the above, Ordinary Kriging is applied to three-dimensional radar rainfall data to estimate rainfall rate at ground level. Keywords: ground clutter, data infilling, Ordinary Kriging, nearest neighbours, Singular Value Decomposition, border tracing, computation time, ground level rainfall estimation

  18. Hydrologic applications of weather radar

    Seo, Dong-Jun; Habib, Emad; Andrieu, Hervé; Morin, Efrat

    2015-12-01

    By providing high-resolution quantitative precipitation information (QPI), weather radars have revolutionized hydrology in the last two decades. With the aid of GIS technology, radar-based quantitative precipitation estimates (QPE) have enabled routine high-resolution hydrologic modeling in many parts of the world. Given the ever-increasing need for higher-resolution hydrologic and water resources information for a wide range of applications, one may expect that the use of weather radar will only grow. Despite the tremendous progress, a number of significant scientific, technological and engineering challenges remain to realize its potential. New challenges are also emerging as new areas of applications are discovered, explored and pursued. The purpose of this special issue is to provide the readership with some of the latest advances, lessons learned, experiences gained, and science issues and challenges related to hydrologic applications of weather radar. The special issue features 20 contributions on various topics which reflect the increasing diversity as well as the areas of focus in radar hydrology today. The contributions may be grouped as follows:

  19. Preliminary Statistics from the NASA Alphasat Beacon Receiver in Milan, Italy

    Nessel, James; Zemba, Michael; Morse, Jacquelynne; Luini, Lorenzo; Riva, Carlo

    2015-01-01

    NASA Glenn Research Center (GRC) and the Politecnico di Milano (POLIMI) have initiated a joint propagation campaign within the framework of the Alphasat propagation experiment to characterize rain attenuation, scintillation, and gaseous absorption effects of the atmosphere in the 40 gigahertz band. NASA GRC has developed and installed a K/Q-band (20/40 gigahertz) beacon receiver at the POLIMI campus in Milan, Italy, which receives the 20/40 gigahertz signals broadcast from the Alphasat Aldo Paraboni TDP no. 5 beacon payload. The primary goal of these measurements is to develop a physical model to improve predictions of communications systems performance within the Q-band. Herein, we provide an overview of the design and data calibration procedure, and present 6 months of preliminary statistics of the NASA propagation terminal, which has been installed and operating in Milan since May 2014. The Q-band receiver has demonstrated a dynamic range of 40 decibels at an 8-hertz sampling rate. A weather station with an optical disdrometer is also installed to characterize rain drop size distribution for correlation with physical based models.

  20. Performance Evaluation of Beacon-Enabled Mode for IEEE 802.15.4 Wireless Sensor Network

    M. Udin Harun Al Rasyid

    2013-12-01

    Full Text Available IEEE 802.15.5 standard support structure of star and peer-to-peer network formation. Strating from these, the cluster tree network can be built as a special case of peer-to-peer network to increse coverage area. In this paper, we provide an performance evaluation of beacon- enabled mode for IEEE 802.15.4 wireless sensor network on star and cluster topology in order to get the maximum result to apply the appropriate topology model as needed. We conduct analysis on each topology model by using the numbers of nodes from 10 nodes to 100 nodes to analyze throughput, delay, energy consumption, and probability success packet by using NS2 simulator. The simulation results show that the throughput and the probability of success packet of cluster topology are higher than that of star topology, and the energy consumption of cluster topology is lesser than that of star topology. However, cluster topology increases the delay more than star topology. Keywords: IEEE 802.15.4, wireless sensor network, beacon-enabled mode, topology, csma/ca

  1. Secure Utilization of Beacons and UAVs in Emergency Response Systems for Building Fire Hazard.

    Seo, Seung-Hyun; Choi, Jung-In; Song, Jinseok

    2017-09-25

    An intelligent emergency system for hazard monitoring and building evacuation is a very important application area in Internet of Things (IoT) technology. Through the use of smart sensors, such a system can provide more vital and reliable information to first-responders and also reduce the incidents of false alarms. Several smart monitoring and warning systems do already exist, though they exhibit key weaknesses such as a limited monitoring coverage and security, which have not yet been sufficiently addressed. In this paper, we propose a monitoring and emergency response method for buildings by utilizing beacons and Unmanned Aerial Vehicles (UAVs) on an IoT security platform. In order to demonstrate the practicability of our method, we also implement a proof of concept prototype, which we call the UAV-EMOR (UAV-assisted Emergency Monitoring and Response) system. Our UAV-EMOR system provides the following novel features: (1) secure communications between UAVs, smart sensors, the control server and a smartphone app for security managers; (2) enhanced coordination between smart sensors and indoor/outdoor UAVs to expand real-time monitoring coverage; and (3) beacon-aided rescue and building evacuation.

  2. Palindromic Molecule Beacon-Based Cascade Amplification for Colorimetric Detection of Cancer Genes.

    Shen, Zhi-Fa; Li, Feng; Jiang, Yi-Fan; Chen, Chang; Xu, Huo; Li, Cong-Cong; Yang, Zhe; Wu, Zai-Sheng

    2018-03-06

    A highly sensitive and selective colorimetric assay based on a multifunctional molecular beacon with palindromic tail (PMB) was proposed for the detection of target p53 gene. The PMB probe can serve as recognition element, primer, and polymerization template and contains a nicking site and a C-rich region complementary to a DNAzyme. In the presence of target DNA, the hairpin of PMB is opened, and the released palindromic tails intermolecularly hybridize with each other, triggering the autonomous polymerization/nicking/displacement cycles. Although only one type of probe is involved, the system can execute triple and continuous polymerization strand displacement amplifications, generating large amounts of G-quadruplex fragments. These G-rich fragments can bind to hemin and form the DNAzymes that possess the catalytic activity similar to horseradish peroxidase, catalyzing the oxidation of ABTS by H 2 O 2 and producing the colorimetric signal. Utilizing the newly proposed sensing system, target DNA can be detected down to 10 pM with a linear response range from 10 pM to 200 nM, and mutant target DNAs are able to be distinguished even by the naked eye. The desirable detection sensitivity, high specificity, and operation convenience without any separation step and chemical modification demonstrate that the palindromic molecular beacon holds the potential for detecting and monitoring a variety of nucleic acid-related biomarkers.

  3. A Two-Layer Method for Sedentary Behaviors Classification Using Smartphone and Bluetooth Beacons.

    Cerón, Jesús D; López, Diego M; Hofmann, Christian

    2017-01-01

    Among the factors that outline the health of populations, person's lifestyle is the more important one. This work focuses on the caracterization and prevention of sedentary lifestyles. A sedentary behavior is defined as "any waking behavior characterized by an energy expenditure of 1.5 METs (Metabolic Equivalent) or less while in a sitting or reclining posture". To propose a method for sedentary behaviors classification using a smartphone and Bluetooth beacons considering different types of classification models: personal, hybrid or impersonal. Following the CRISP-DM methodology, a method based on a two-layer approach for the classification of sedentary behaviors is proposed. Using data collected from a smartphones' accelerometer, gyroscope and barometer; the first layer classifies between performing a sedentary behavior and not. The second layer of the method classifies the specific sedentary activity performed using only the smartphone's accelerometer and barometer data, but adding indoor location data, using Bluetooth Low Energy (BLE) beacons. To improve the precision of the classification, both layers implemented the Random Forest algorithm and the personal model. This study presents the first available method for the automatic classification of specific sedentary behaviors. The layered classification approach has the potential to improve processing, memory and energy consumption of mobile devices and wearables used.

  4. Temporal change of EIA asymmetry revealed by a beacon receiver network in Southeast Asia

    Watthanasangmechai, Kornyanat; Yamamoto, Mamoru; Saito, Akinori; Maruyama, Takashi; Yokoyama, Tatsuhiro; Nishioka, Michi; Ishii, Mamoru

    2015-05-01

    To reveal the temporal change of the equatorial ionization anomaly (EIA) asymmetry, a multipoint satellite-ground beacon experiment was conducted along the meridional plane of the Thailand-Indonesia sector. The observation includes one station near the magnetic equator and four stations at off-equator latitudes. This is the first EIA asymmetry study with high spatial resolution using GNU Radio Beacon Receiver (GRBR) observations in Southeast Asia. GRBR-total electron contents (TECs) from 97 polar-orbit satellite passes in March 2012 were analyzed in this study. Successive passes captured rapid evolution of EIA asymmetry, especially during geomagnetic disturbances. The penetrating electric fields that occur during geomagnetic disturbed days are not the cause of the asymmetry. Instead, high background TEC associated with an intense electric field empowers the neutral wind to produce severe asymmetry of the EIA. Such rapid evolution of EIA asymmetry was not seen during nighttime, when meridional wind mainly controlled the asymmetric structures. Additional data are necessary to identify the source of the variations, i.e., atmospheric waves. Precisely capturing the locations of the crests and the evolution of the asymmetry enhances understanding of the temporal change of EIA asymmetry at the local scale and leads to a future local modeling for TEC prediction in Southeast Asia.

  5. Perancangan Prototipe Receiver Beacon Black Box Locator Acoustic 37,5 kHz Pingers

    RUSTAMAJI RUSTAMAJI

    2016-01-01

    When an aircraft caught in an accident and crashes into the water, its location can be detected using a device called a receiver beacon black box locator acoustic (pingers receiver. The pingers receiver functioned as a reciever signal with 37,5 kHz ± 1 kHz frequency from trnasmitter pingers or Underwater Locator Beacon (ULB which is on air plane black blox. In this research made design pingers receiver composed of a series of  Band Pass Filter (BPF, envelope detector, audio amplifier, and loud speaker. The signal of 37,5 kHz ± 1 kHz  frequency sent by pingers transmitter will bereceived by pingers receiver, after which the signal will be processed by the Band Pass Filter (BPF circuit before being detected by envelope detector for take back the signal information which like pulse signal with 10ms width and 1 second interval as pingers signal tha can  be to  be heard by human ear. Based on the  design that  was made, the signal ouput generated by the prototype has a 14 ms width with 1 second interval. Keywords: pingers receiver, band pass filter (BPF, envelope detector, loud speaker.

  6. Extended Target Recognition in Cognitive Radar Networks

    Xiqin Wang

    2010-11-01

    Full Text Available We address the problem of adaptive waveform design for extended target recognition in cognitive radar networks. A closed-loop active target recognition radar system is extended to the case of a centralized cognitive radar network, in which a generalized likelihood ratio (GLR based sequential hypothesis testing (SHT framework is employed. Using Doppler velocities measured by multiple radars, the target aspect angle for each radar is calculated. The joint probability of each target hypothesis is then updated using observations from different radar line of sights (LOS. Based on these probabilities, a minimum correlation algorithm is proposed to adaptively design the transmit waveform for each radar in an amplitude fluctuation situation. Simulation results demonstrate performance improvements due to the cognitive radar network and adaptive waveform design. Our minimum correlation algorithm outperforms the eigen-waveform solution and other non-cognitive waveform design approaches.

  7. German Radar Observation Shuttle Experiment (ROSE)

    Sleber, A. J.; Hartl, P.; Haydn, R.; Hildebrandt, G.; Konecny, G.; Muehlfeld, R.

    1984-01-01

    The success of radar sensors in several different application areas of interest depends on the knowledge of the backscatter of radar waves from the targets of interest, the variance of these interaction mechanisms with respect to changing measurement parameters, and the determination of the influence of he measuring systems on the results. The incidence-angle dependency of the radar cross section of different natural targets is derived. Problems involved by the combination of data gained with different sensors, e.g., MSS-, TM-, SPOTand SAR-images are analyzed. Radar cross-section values gained with ground-based radar spectrometers and spaceborne radar imaging, and non-imaging scatterometers and spaceborne radar images from the same areal target are correlated. The penetration of L-band radar waves into vegetated and nonvegetated surfaces is analyzed.

  8. NOAA NEXt-Generation RADar (NEXRAD) Products

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset consists of Level III weather radar products collected from Next-Generation Radar (NEXRAD) stations located in the contiguous United States, Alaska,...

  9. MST radar data-base management

    Wickwar, V. B.

    1983-01-01

    Data management for Mesospheric-Stratospheric-Tropospheric, (MST) radars is addressed. An incoherent-scatter radar data base is discussed in terms of purpose, centralization, scope, and nature of the data base management system.

  10. Design of multi-frequency CW radars

    Jankiraman, Mohinder

    2007-01-01

    This book deals with the basic theory for design and analysis of Low Probability of Intercept (LPI) radar systems. The design of one such multi-frequency high resolution LPI radar, PANDORA, is covered.

  11. Modern approach to relativity theory (radar formulation)

    Strel'tsov, V.N.

    1991-01-01

    The main peculiarities of the radar formulation of the relativity theory are presented. This formulation operates with the retarded (light) distances and relativistic or radar length introduced on their basis. 21 refs.; 1 tab

  12. Meteor detection on ST (MST) radars

    Avery, S.K.

    1987-01-01

    The ability to detect radar echoes from backscatter due to turbulent irregularities of the radio refractive index in the clear atmosphere has lead to an increasing number of established mesosphere - stratosphere - troposphere (MST or ST) radars. Humidity and temperature variations are responsible for the echo in the troposphere and stratosphere and turbulence acting on electron density gradients provides the echo in the mesosphere. The MST radar and its smaller version, the ST radar, are pulsed Doppler radars operating in the VHF - UHF frequency range. These echoes can be used to determine upper atmosphere winds at little extra cost to the ST radar configuration. In addition, the meteor echoes can supplement mesospheric data from an MST radar. The detection techniques required on the ST radar for delineating meteor echo returns are described

  13. SAR Ambiguity Study for the Cassini Radar

    Hensley, Scott; Im, Eastwood; Johnson, William T. K.

    1993-01-01

    The Cassini Radar's synthetic aperture radar (SAR) ambiguity analysis is unique with respect to other spaceborne SAR ambiguity analyses owing to the non-orbiting spacecraft trajectory, asymmetric antenna pattern, and burst mode of data collection. By properly varying the pointing, burst mode timing, and radar parameters along the trajectory this study shows that the signal-to-ambiguity ratio of better than 15 dB can be achieved for all images obtained by the Cassini Radar.

  14. Radar operation in a hostile electromagnetic environment

    Doerry, Armin Walter

    2014-03-01

    Radar ISR does not always involve cooperative or even friendly targets. An adversary has numerous techniques available to him to counter the effectiveness of a radar ISR sensor. These generally fall under the banner of jamming, spoofing, or otherwise interfering with the EM signals required by the radar sensor. Consequently mitigation techniques are prudent to retain efficacy of the radar sensor. We discuss in general terms a number of mitigation techniques.

  15. Radar reflection off extensive air showers

    Stasielak, J; Bertaina, M; Blümer, J; Chiavassa, A; Engel, R; Haungs, A; Huege, T; Kampert, K -H; Klages, H; Kleifges, M; Krömer, O; Ludwig, M; Mathys, S; Neunteufel, P; Pekala, J; Rautenberg, J; Riegel, M; Roth, M; Salamida, F; Schieler, H; Šmída, R; Unger, M; Weber, M; Werner, F; Wilczyński, H; Wochele, J

    2012-01-01

    We investigate the possibility of detecting extensive air showers by the radar technique. Considering a bistatic radar system and different shower geometries, we simulate reflection of radio waves off the static plasma produced by the shower in the air. Using the Thomson cross-section for radio wave reflection, we obtain the time evolution of the signal received by the antennas. The frequency upshift of the radar echo and the power received are studied to verify the feasibility of the radar detection technique.

  16. Compressive sensing for urban radar

    Amin, Moeness

    2014-01-01

    With the emergence of compressive sensing and sparse signal reconstruction, approaches to urban radar have shifted toward relaxed constraints on signal sampling schemes in time and space, and to effectively address logistic difficulties in data acquisition. Traditionally, these challenges have hindered high resolution imaging by restricting both bandwidth and aperture, and by imposing uniformity and bounds on sampling rates.Compressive Sensing for Urban Radar is the first book to focus on a hybrid of two key areas: compressive sensing and urban sensing. It explains how reliable imaging, tracki

  17. Wind Turbine Radar Cross Section

    David Jenn

    2012-01-01

    Full Text Available The radar cross section (RCS of a wind turbine is a figure of merit for assessing its effect on the performance of electronic systems. In this paper, the fundamental equations for estimating the wind turbine clutter signal in radar and communication systems are presented. Methods of RCS prediction are summarized, citing their advantages and disadvantages. Bistatic and monostatic RCS patterns for two wind turbine configurations, a horizontal axis three-blade design and a vertical axis helical design, are shown. The unique electromagnetic scattering features, the effect of materials, and methods of mitigating wind turbine clutter are also discussed.

  18. 75 FR 20364 - Public Buildings Service; Key Largo Beacon Annex Site; Key Largo, FL; Transfer of Property

    2010-04-19

    ... GENERAL SERVICES ADMINISTRATION [Wildlife Order 187; 4-D-FL-1218] Public Buildings Service; Key Largo Beacon Annex Site; Key Largo, FL; Transfer of Property Pursuant to section 2 of Public Law 537, 80th Congress, approved May 19, 1948 (16 U.S.C. 667c), notice is hereby given that: 1. The General...

  19. Guiding Math Students to Campus Services: An Impact Evaluation of the Beacon Program at South Texas College

    Visher, Mary; Butcher, Kristin F.; Cerna, Oscar S.

    2011-01-01

    This research rigorously evaluates whether a low-cost intervention can improve students' performance in developmental math. The "Beacon Mentoring Program" was developed at South Texas College by professors, administrators, and staff at the college. Surveys of students revealed that many did not have someone on campus whom they felt they…

  20. Beacon Charter School Needs a School: A Case of Capital Outlay of Charters in a Public District

    Wronowski, Meredith L.

    2017-01-01

    The case study presented below is a representation of a real-world, ongoing situation involving a public school district's capital outlay for charter schools within its boundaries. One particular charter, Beacon Charter School, was promised a permanent building by the public school district that also acts as its authorizer. However, recent events…

  1. A molecular-beacon-based asymmetric PCR assay for easy visualization of amplicons in the diagnosis of trichomoniasis.

    Sonkar, Subash C; Sachdev, Divya; Mishra, Prashant K; Kumar, Anita; Mittal, Pratima; Saluja, Daman

    2016-12-15

    The currently available nucleic acid amplification tests (NAATs) for trichomoniasis are accurate, quick and confirmative with superior sensitivity than traditional culture-based microbiology assays. However, these assays are associated with problems of carry over contamination, false positive results, requirement of technical expertise for performance and detection of end product. Hence, a diagnostic assay with easy visualization of the amplified product will be profitable. An in-house, rapid, sensitive, specific molecular-beacon-based PCR assay, using primers against pfoB gene of Trichomonas vaginalis, was developed and evaluated using dry ectocervical swabs (n=392) from symptomatic females with vaginal discharge. Total DNA was isolated and used as template for the PCR assays. The performance and reproducibility of PCR assay was evaluated by composite reference standard (CRS). For easy visualization of the amplified product, molecular-beacon was designed and amplicons were visualized directly using fluorescent handheld dark reader or by Micro-Plate Reader. Molecular-beacons are single-stranded hairpin shaped nucleic acid probes composed of a stem, with fluorophore/quencher pair and a loop region complementary to the desired DNA. The beacon-based PCR assay designed in the present study is highly specific as confirmed by competition experiments and extremely sensitive with detection limit of 20fg of genomic DNA (3-4 pathogens). The minimum infrastructure requirement and ease to perform the assay makes this method highly useful for resource poor countries for better disease management. Copyright © 2016 Elsevier B.V. All rights reserved.

  2. A quencher-free molecular beacon design based on pyrene excimer fluorescence using pyrene-labeled UNA (unlocked nucleic acid)

    Karlsen, Kasper Kannegård; Okholm, Anders Hauge; Kjems, Jørgen

    2013-01-01

    A quencher-free molecular beacon capable of generating pyrene excimer fluorescence has been constructed using strategically positioned pyrene-UNA monomers. Hybridization of a fully complementary RNA target was accompanied by a pyrene excimer emission increase of more than 900%, and detection of RNA...

  3. BEACON/MOD2A: a computer program for subcompartment analysis of nuclear reactor containment. A user's manual

    Wells, R.A.

    1979-03-01

    The BEACON code is a Best Estimate Advanced Containment code which being developed by EG and G, Idaho, Inc., at the Idaho National Engineering Laboratory. The program is designed to perform a best estimate analysis of the flow of a mixture of air, water, and steam in a nuclear reactor containment system under loss-of-coolant accident conditions. The code can simulate two-component, two-phase fluid flow in complex geometries using a combination of two-dimensional, one-dimensional, and lumped-parameter representations for the various parts of the system. The current version of BEACON, which is designated BEACON/MOD2A, contains mass and heat transfer models for wall film and for wall conduction. It is suitable for the evaluation of short term transients in PWR dry containment systems. This manual describes the models employed in BEACON/MOD2A and specifies code implementation requirements. It provides application information for input data preparation and for output data interpretation

  4. Principles of modern radar advanced techniques

    Melvin, William

    2012-01-01

    Principles of Modern Radar: Advanced Techniques is a professional reference for practicing engineers that provides a stepping stone to advanced practice with in-depth discussions of the most commonly used advanced techniques for radar design. It will also serve advanced radar academic and training courses with a complete set of problems for students as well as solutions for instructors.

  5. Efficient Ways to Learn Weather Radar Polarimetry

    Cao, Qing; Yeary, M. B.; Zhang, Guifu

    2012-01-01

    The U.S. weather radar network is currently being upgraded with dual-polarization capability. Weather radar polarimetry is an interdisciplinary area of engineering and meteorology. This paper presents efficient ways to learn weather radar polarimetry through several basic and practical topics. These topics include: 1) hydrometeor scattering model…

  6. Radar geomorphology of coastal and wetland environments

    Lewis, A. J.; Macdonald, H. C.

    1973-01-01

    Details regarding the collection of radar imagery over the past ten years are considered together with the geomorphic, geologic, and hydrologic data which have been extracted from radar imagery. Recent investigations were conducted of the Louisiana swamp marsh and the Oregon coast. It was found that radar imagery is a useful tool to the scientist involved in wetland research.

  7. 46 CFR 184.404 - Radars.

    2010-10-01

    ... within one mile of land must be fitted with a FCC Type Accepted general marine radar system for surface... Federal Communications Commission (FCC) type accepted general marine radar system for surface navigation... 46 Shipping 7 2010-10-01 2010-10-01 false Radars. 184.404 Section 184.404 Shipping COAST GUARD...

  8. Design and Practical Evaluation of a Family of Lightweight Protocols for Heterogeneous Sensing through BLE Beacons in IoT Telemetry Applications.

    Hernández-Rojas, Dixys L; Fernández-Caramés, Tiago M; Fraga-Lamas, Paula; Escudero, Carlos J

    2017-12-27

    The Internet of Things (IoT) involves a wide variety of heterogeneous technologies and resource-constrained devices that interact with each other. Due to such constraints, IoT devices usually require lightweight protocols that optimize the use of resources and energy consumption. Among the different commercial IoT devices, Bluetooth and Bluetooth Low Energy (BLE)-based beacons, which broadcast periodically certain data packets to notify their presence, have experienced a remarkable growth, specially due to their application in indoor positioning systems. This article proposes a family of protocols named Lightweight Protocol for Sensors (LP4S) that provides fast responses and enables plug-and-play mechanisms that allow IoT telemetry systems to discover new nodes and to describe and auto-register the sensors and actuators connected to a beacon. Thus, three protocols are defined depending on the beacon hardware characteristics: LP4S-6 (for resource-constraint beacons), LP4S-X (for more powerful beacons) and LP4S-J (for beacons able to run complex firmware). In order to demonstrate the capabilities of the designed protocols, the most restrictive (LP4S-6) is tested after implementing it for a telemetry application in a beacon based on Eddystone (Google's open beacon format). Thus, the beacon specification is extended in order to increase its ability to manage unlimited sensors in a telemetry system without interfering in its normal operation with Eddystone frames. The performed experiments show the feasibility of the proposed solution and its superiority, in terms of latency and energy consumption, with respect to approaches based on Generic Attribute Profile (GATT) when multiple users connect to a mote or in scenarios where latency is not a restriction, but where low-energy consumption is essential.

  9. Design and Practical Evaluation of a Family of Lightweight Protocols for Heterogeneous Sensing through BLE Beacons in IoT Telemetry Applications

    2017-01-01

    The Internet of Things (IoT) involves a wide variety of heterogeneous technologies and resource-constrained devices that interact with each other. Due to such constraints, IoT devices usually require lightweight protocols that optimize the use of resources and energy consumption. Among the different commercial IoT devices, Bluetooth and Bluetooth Low Energy (BLE)-based beacons, which broadcast periodically certain data packets to notify their presence, have experienced a remarkable growth, specially due to their application in indoor positioning systems. This article proposes a family of protocols named Lightweight Protocol for Sensors (LP4S) that provides fast responses and enables plug-and-play mechanisms that allow IoT telemetry systems to discover new nodes and to describe and auto-register the sensors and actuators connected to a beacon. Thus, three protocols are defined depending on the beacon hardware characteristics: LP4S-6 (for resource-constraint beacons), LP4S-X (for more powerful beacons) and LP4S-J (for beacons able to run complex firmware). In order to demonstrate the capabilities of the designed protocols, the most restrictive (LP4S-6) is tested after implementing it for a telemetry application in a beacon based on Eddystone (Google’s open beacon format). Thus, the beacon specification is extended in order to increase its ability to manage unlimited sensors in a telemetry system without interfering in its normal operation with Eddystone frames. The performed experiments show the feasibility of the proposed solution and its superiority, in terms of latency and energy consumption, with respect to approaches based on Generic Attribute Profile (GATT) when multiple users connect to a mote or in scenarios where latency is not a restriction, but where low-energy consumption is essential. PMID:29280975

  10. Design and Practical Evaluation of a Family of Lightweight Protocols for Heterogeneous Sensing through BLE Beacons in IoT Telemetry Applications

    Dixys L. Hernández-Rojas

    2017-12-01

    Full Text Available The Internet of Things (IoT involves a wide variety of heterogeneous technologies and resource-constrained devices that interact with each other. Due to such constraints, IoT devices usually require lightweight protocols that optimize the use of resources and energy consumption. Among the different commercial IoT devices, Bluetooth and Bluetooth Low Energy (BLE-based beacons, which broadcast periodically certain data packets to notify their presence, have experienced a remarkable growth, specially due to their application in indoor positioning systems. This article proposes a family of protocols named Lightweight Protocol for Sensors (LP4S that provides fast responses and enables plug-and-play mechanisms that allow IoT telemetry systems to discover new nodes and to describe and auto-register the sensors and actuators connected to a beacon. Thus, three protocols are defined depending on the beacon hardware characteristics: LP4S-6 (for resource-constraint beacons, LP4S-X (for more powerful beacons and LP4S-J (for beacons able to run complex firmware. In order to demonstrate the capabilities of the designed protocols, the most restrictive (LP4S-6 is tested after implementing it for a telemetry application in a beacon based on Eddystone (Google’s open beacon format. Thus, the beacon specification is extended in order to increase its ability to manage unlimited sensors in a telemetry system without interfering in its normal operation with Eddystone frames. The performed experiments show the feasibility of the proposed solution and its superiority, in terms of latency and energy consumption, with respect to approaches based on Generic Attribute Profile (GATT when multiple users connect to a mote or in scenarios where latency is not a restriction, but where low-energy consumption is essential.

  11. Data governance and data sharing agreements for community-wide health information exchange: lessons from the beacon communities.

    Allen, Claudia; Des Jardins, Terrisca R; Heider, Arvela; Lyman, Kristin A; McWilliams, Lee; Rein, Alison L; Schachter, Abigail A; Singh, Ranjit; Sorondo, Barbara; Topper, Joan; Turske, Scott A

    2014-01-01

    Unprecedented efforts are underway across the United States to electronically capture and exchange health information to improve health care and population health, and reduce costs. This increased collection and sharing of electronic patient data raises several governance issues, including privacy, security, liability, and market competition. Those engaged in such efforts have had to develop data sharing agreements (DSAs) among entities involved in information exchange, many of whom are "nontraditional" health care entities and/or new partners. This paper shares lessons learned based on the experiences of six federally funded communities participating in the Beacon Community Cooperative Agreement Program, and offers guidance for navigating data governance issues and developing DSAs to facilitate community-wide health information exchange. While all entities involved in electronic data sharing must address governance issues and create DSAs accordingly, until recently little formal guidance existed for doing so - particularly for community-based initiatives. Despite this lack of guidance, together the Beacon Communities' experiences highlight promising strategies for navigating complex governance issues, which may be useful to other entities or communities initiating information exchange efforts to support delivery system transformation. For the past three years, AcademyHealth has provided technical assistance to most of the 17 Beacon Communities, 6 of whom contributed to this collaborative writing effort. Though these communities varied widely in terms of their demographics, resources, and Beacon-driven priorities, common themes emerged as they described their approaches to data governance and DSA development. The 6 Beacon Communities confirmed that DSAs are necessary to satisfy legal and market-based concerns, and they identified several specific issues, many of which have been noted by others involved in network data sharing initiatives. More importantly, these

  12. [Molecular beacon based PNA-FISH method combined with fluorescence scanning for rapid detection of Listeria monocytogenes].

    Wu, Shan; Zhang, Xiaofeng; Shuai, Jiangbing; Li, Ke; Yu, Huizhen; Jin, Chenchen

    2016-07-04

    To simplify the PNA-FISH (Peptide nucleic acid-fluorescence in situ hybridization) test, molecular beacon based PNA probe combined with fluorescence scanning detection technology was applied to replace the original microscope observation to detect Listeria monocytogenes The 5′ end and 3′ end of the L. monocytogenes specific PNA probes were labeled with the fluorescent group and the quenching group respectively, to form a molecular beacon based PNA probe. When PNA probe used for fluorescence scanning and N1 treatment as the control, the false positive rate was 11.4%, and the false negative rate was 0; when N2 treatment as the control, the false positive rate decreased to 4.3%, but the false negative rate rose to 18.6%. When beacon based PNA probe used for fluorescence scanning, taken N1 treatment as blank control, the false positive rate was 8.6%, and the false negative rate was 1.4%; taken N2 treatment as blank control, the false positive rate was 5.7%, and the false negative rate was 1.4%. Compared with PNA probe, molecular beacon based PNA probe can effectively reduce false positives and false negatives. The success rates of hybridization of the two PNA probes were 83.3% and 95.2% respectively; and the rates of the two beacon based PNA probes were 91.7% and 90.5% respectively, which indicated that labeling the both ends of the PNA probe dose not decrease the hybridization rate with the target bacteria. The combination of liquid phase PNA-FISH and fluorescence scanning method, can significantly improve the detection efficiency.

  13. Beacon of Hope? Lessons Learned from Efforts to Reduce Civilian Deaths from Police Shootings in an Australian State.

    Saligari, Jessica; Evans, Richard

    2016-04-01

    In the 1990s, the police service in Victoria, Australia, faced a crisis of community confidence due to a spate of civilian deaths from police shootings. In that decade, twice as many civilians died at the hands of the police in Victoria than in every other Australian state combined. Most of those killed were mentally ill and affected by drugs and alcohol, and were rarely a serious threat except to themselves. The problem was also almost entirely an urban phenomenon. Shootings in rural communities, where mentally ill people were more likely to be personally known to local police, were (and remain) almost unknown. The large number of fatalities was recognised as a serious threat to public confidence, and Victoria Police introduced a ground-breaking training programme, Operation Beacon. Operating procedures and weapons training were fundamentally changed, to focus on de-escalation of conflict and avoiding or minimising police use of force. In the short term, Operation Beacon was successful. Shooting incidents were dramatically reduced. However, during the first decade of the new century, the number of civilians being killed again increased. This article examines Operation Beacon, both as a successful model for reducing civilian deaths at the hand of police and as a cautionary tale for police reform. We argue that the lessons of Operation Beacon have been gradually forgotten and that old habits and attitudes resurfaced. Fatal shootings of mentally ill civilians can be prevented, but if success is to be other than temporary, the Beacon philosophy must be continually reemphasised by police management.

  14. Radioprotection and radar: practical aspects

    Pepersack, J.P.

    1979-01-01

    The author, on basis of his experience in radar-radioprotection, exposes the standard and security norms and recommendations to be applied for the preventive adapation of the work-areas as well as for the follow-up of the exposed workers. (author)

  15. Synthetic aperture radar capabilities in development

    Miller, M. [Lawrence Livermore National Lab., CA (United States)

    1994-11-15

    The Imaging and Detection Program (IDP) within the Laser Program is currently developing an X-band Synthetic Aperture Radar (SAR) to support the Joint US/UK Radar Ocean Imaging Program. The radar system will be mounted in the program`s Airborne Experimental Test-Bed (AETB), where the initial mission is to image ocean surfaces and better understand the physics of low grazing angle backscatter. The Synthetic Aperture Radar presentation will discuss its overall functionality and a brief discussion on the AETB`s capabilities. Vital subsystems including radar, computer, navigation, antenna stabilization, and SAR focusing algorithms will be examined in more detail.

  16. Radar application in void and bar detection

    Amry Amin Abas; Mohamad Pauzi Ismail; Suhairy Sani

    2003-01-01

    Radar is one of the new non-destructive testing techniques for concrete and structures inspection. Radar is a non-ionizing electromagnetic wave that can penetrate deep into concrete or soil in about several tenths of meters. Method of inspection using radar enables us to perform high resolution detection, imaging and mapping of subsurface concrete and soil condition. This paper will discuss the use of radar for void and bar detection and sizing. The samples used in this paper are custom made samples and comparison will be made to validate the use of radar in detecting, locating and also size determination of voids and bars. (Author)

  17. Radar meteor rates and solar activity

    Prikryl, P.

    1983-01-01

    The short-term variation of diurnal radar meteor rates with solar activity represented by solar microwave flux Fsub(10.7), and sunspots relative number Rsub(z), is investigated. Applying the superposed-epoch analysis to the observational material of radar meteor rates from Christchurch (1960-61 and 1963-65), a decrease in the recorded radar rates is found during days of enhanced solar activity. No effect of geomagnetic activity similar to the one reported for the Swedish and Canadian radar meteor data was found by the author in the Christchurch data. A possible explanation of the absence of the geomagnetic effect on radar meteor rates from New Zealand due to a lower echo ceiling height of the Christchurch radar is suggested. The variation of the atmospheric parameters as a possible cause of the observed variation in radar meteor rates is also discussed. (author)

  18. Isothermal amplification detection of nucleic acids by a double-nicked beacon.

    Shi, Chao; Zhou, Meiling; Pan, Mei; Zhong, Guilin; Ma, Cuiping

    2016-03-01

    Isothermal and rapid amplification detection of nucleic acids is an important technology in environmental monitoring, foodborne pathogen detection, and point-of-care clinical diagnostics. Here we have developed a novel method of isothermal signal amplification for single-stranded DNA (ssDNA) detection. The ssDNA target could be used as an initiator, coupled with a double-nicked molecular beacon, to originate amplification cycles, achieving cascade signal amplification. In addition, the method showed good specificity and strong anti-jamming capability. Overall, it is a one-pot and isothermal strand displacement amplification method without the requirement of a stepwise procedure, which greatly simplifies the experimental procedure and decreases the probability of contamination of samples. With its advantages, the method would be very useful to detect nucleic acids in point-of-care or field use. Copyright © 2015 Elsevier Inc. All rights reserved.

  19. Simple fluorescence-based detection of protein kinase A activity using a molecular beacon probe.

    Ma, Changbei; Lv, Xiaoyuan; Wang, Kemin; Jin, Shunxin; Liu, Haisheng; Wu, Kefeng; Zeng, Weimin

    2017-11-02

    Protein kinase A was detected by quantifying the amount of ATP used after a protein kinase reaction. The ATP assay was performed using the T4 DNA ligase and a molecular beacon (MB). In the presence of ATP, DNA ligase catalyzed the ligation of short DNA. The ligation product then hybridized to MB, resulting in a fluorescence enhancement of the MB. This assay was capable of determining protein kinase A in the range of 12.5∼150 nM, with a detection limit of 1.25 nM. Furthermore, this assay could also be used to investigate the effect of genistein on protein kinase A. It was a universal, non-radioisotopic, and homogeneous method for assaying protein kinase A.

  20. Considerations for Community-Based mHealth Initiatives: Insights From Three Beacon Communities

    2013-01-01

    Mobile health (mHealth) is gaining widespread attention for its potential to engage patients in their health and health care in their daily lives. Emerging evidence suggests that mHealth interventions can be used effectively to support behavior change, but numerous challenges remain when implementing these programs at the community level. This paper provides an overview of considerations when implementing community-based mHealth initiatives, based on the experiences of three Beacon Communities across the United States that have launched text messaging (short message service, SMS) pilot programs aimed at diabetes risk reduction and disease management. The paper addresses lessons learned and suggests strategies to overcome challenges related to developing text message content, conducting marketing and outreach, enrolling participants, engaging providers, evaluating program effectiveness, and sustaining and scaling the programs. PMID:24128406

  1. Facile conversion of ATP-binding RNA aptamer to quencher-free molecular aptamer beacon.

    Park, Yoojin; Nim-Anussornkul, Duangrat; Vilaivan, Tirayut; Morii, Takashi; Kim, Byeang Hyean

    2018-01-15

    We have developed RNA-based quencher-free molecular aptamer beacons (RNA-based QF-MABs) for the detection of ATP, taking advantage of the conformational changes associated with ATP binding to the ATP-binding RNA aptamer. The RNA aptamer, with its well-defined structure, was readily converted to the fluorescence sensors by incorporating a fluorophore into the loop region of the hairpin structure. These RNA-based QF-MABs exhibited fluorescence signals in the presence of ATP relative to their low background signals in the absence of ATP. The fluorescence emission intensity increased upon formation of a RNA-based QF-MAB·ATP complex. Copyright © 2017 Elsevier Ltd. All rights reserved.

  2. Pyrene functionalized molecular beacon with pH-sensitive i-motif in a loop.

    Dembska, Anna; Juskowiak, Bernard

    2015-01-01

    In this work, we present a spectral characterization of pH-sensitive system, which combines the i-motif properties with the spatially sensitive fluorescence signal of pyrene molecules attached to hairpin ends. The excimer production (fluorescence max. ∼480 nm) by pyrene labels at the ends of the molecular beacon is driven by pH-dependent i-motif formation in the loop. To illustrate the performance and reversible work of our systems, we performed the experiments with repeatedly pH cycling between pH values of 7.5±0.3 and 6.5±0.3. The sensor gives analytical response in excimer-monomer switching mode in narrow pH range (1.5 pH units) and exhibits high pH resolution (0.1 pH unit). Copyright © 2015 Elsevier B.V. All rights reserved.

  3. Nanomechanical DNA origami 'single-molecule beacons' directly imaged by atomic force microscopy

    Kuzuya, Akinori; Sakai, Yusuke; Yamazaki, Takahiro; Xu, Yan; Komiyama, Makoto

    2011-01-01

    DNA origami involves the folding of long single-stranded DNA into designed structures with the aid of short staple strands; such structures may enable the development of useful nanomechanical DNA devices. Here we develop versatile sensing systems for a variety of chemical and biological targets at molecular resolution. We have designed functional nanomechanical DNA origami devices that can be used as 'single-molecule beacons', and function as pinching devices. Using 'DNA origami pliers' and 'DNA origami forceps', which consist of two levers ~170 nm long connected at a fulcrum, various single-molecule inorganic and organic targets ranging from metal ions to proteins can be visually detected using atomic force microscopy by a shape transition of the origami devices. Any detection mechanism suitable for the target of interest, pinching, zipping or unzipping, can be chosen and used orthogonally with differently shaped origami devices in the same mixture using a single platform. PMID:21863016

  4. ATS-6 radio beacon electron content measurements at Ootacamund, India, October 1975-July 1976

    Bouwer, S.D.; Davies, K.; Donnelly, R.F.; Grubb, R.N.; Jones, J.E.

    1980-03-01

    An atlas of total slant-path columnar electron content data measured between the ATS-6 satellite and Ootacamund, India, a site near the magnetic Equator is presented. Although these measurements were taken during a solar minimum, the general level of flare and geomagnetic activity that occurred during the observation period is summarized. These total content (N(T)) data were derived from the modulation phase (group delay) of a carrier signal transmitted from the geostationary satellite's Radio Beacon Experiment. This atlas contains two data sets: (1) N(T) as 2-min subsamples digitally recorded between 2 October 1975 and 28 January 1976 corrected for ATS-6 pitch maneuvers and (2) N(T) as 15-min subsamples chart recorded between 21 October 1975 and 22 July 1976 but uncorrected for changes in satellite orientation

  5. Detection of DNA damage based on metal-mediated molecular beacon and DNA strands displacement reaction

    Xiong, Yanxiang; Wei, Min; Wei, Wei; Yin, Lihong; Pu, Yuepu; Liu, Songqin

    2014-01-01

    DNA hairpin structure probes are usually designed by forming intra-molecular duplex based on Watson-Crick hydrogen bonds. In this paper, a molecular beacon based on silver ions-mediated cytosine-Ag+-cytosine base pairs was used to detect DNA. The inherent characteristic of the metal ligation facilitated the design of functional probe and the adjustment of its binding strength compared to traditional DNA hairpin structure probes, which make it be used to detect DNA in a simple, rapid and easy way with the help of DNA strands displacement reaction. The method was sensitive and also possesses the good specificity to differentiate the single base mismatched DNA from the complementary DNA. It was also successfully applied to study the damage effect of classic genotoxicity chemicals such as styrene oxide and sodium arsenite on DNA, which was significant in food science, environmental science and pharmaceutical science.

  6. Considerations for community-based mHealth initiatives: insights from three Beacon Communities.

    Abebe, Nebeyou A; Capozza, Korey L; Des Jardins, Terrisca R; Kulick, David A; Rein, Alison L; Schachter, Abigail A; Turske, Scott A

    2013-10-15

    Mobile health (mHealth) is gaining widespread attention for its potential to engage patients in their health and health care in their daily lives. Emerging evidence suggests that mHealth interventions can be used effectively to support behavior change, but numerous challenges remain when implementing these programs at the community level. This paper provides an overview of considerations when implementing community-based mHealth initiatives, based on the experiences of three Beacon Communities across the United States that have launched text messaging (short message service, SMS) pilot programs aimed at diabetes risk reduction and disease management. The paper addresses lessons learned and suggests strategies to overcome challenges related to developing text message content, conducting marketing and outreach, enrolling participants, engaging providers, evaluating program effectiveness, and sustaining and scaling the programs.

  7. Evaluation of a rectangular rapid flashing beacon system at the Belmont Ridge Road and W&OD Trail mid-block crosswalk.

    2015-05-01

    On April 8, 2013, the Virginia Department of Transportation (VDOT) installed a Rectangular Rapid Flashing Beacon : (RRFB) system at Belmont Ridge Road in Loudoun County that included two units at the Washington and Old Dominion : (W&OD) Trail crossin...

  8. Detection of Candida species in pregnant Chinese women with a molecular beacon method.

    Zhai, Yanhong; Liu, Jing; Zhou, Li; Ji, Tongzhen; Meng, Lingxin; Gao, Yang; Liu, Ran; Wang, Xiao; Li, Lin; Lu, Binghuai; Cao, Zheng

    2018-04-20

    Candida pathogens are commonly found in women and can cause vulvovaginal candidiasis (VVC), whose infection rate is further increased during pregnancy. We aimed to study the Candida prevalence and strain distribution in pregnant Chinese women with a molecular beacon assay. From March 2016 to February 2017, a total of 993 pregnant women attending routine antenatal visits at the Beijing Obstetrics and Gynecology Hospital were enrolled. For Candida detection and identification, a unique molecular beacon assay was presented and compared with a traditional phenotypic method. Antifungal susceptibility was tested with the following agents: 5-flucytosine, amphotericin B, fluconazole, itraconazole and voriconazole. The prevalence of Candida was found to be 21.8 % when using the molecular method and 15.0 % when using the phenotypic method. The distribution of the Candida spp. was listed in order of decreasing prevalence: Candida albicans (79.8 %), Candida glabrata (13.5 %), Candida parapsilosis (3.7 %), Candida krusei (2.2 %) and Candida tropicalis (1.1 %). We found that 90.7 % of the Candida detection results were consistent between the molecular and the phenotypic methods. In the cases where the sequencing analyses for the Candida isolates resulted in inconsistent identification, the molecular method showed higher sensitivity than the phenotypic method (96.0 vs 64.6 %). C. albicans, C. glabrata and C. parapsilosis were essentially susceptible to all five antifungal agents tested, whereas C. tropicalis and C. krusei were susceptible to voriconazole and amphotericin B. By exhibiting good sensitivity and specificity, the molecular assay may offer a fast and accurate Candida screening platform for pregnant women.

  9. Energy optimization for upstream data transfer in 802.15.4 beacon-enabled star formulation

    Liu, Hua; Krishnamachari, Bhaskar

    2008-08-01

    Energy saving is one of the major concerns for low rate personal area networks. This paper models energy consumption for beacon-enabled time-slotted media accessing control cooperated with sleeping scheduling in a star network formulation for IEEE 802.15.4 standard. We investigate two different upstream (data transfer from devices to a network coordinator) strategies: a) tracking strategy: the devices wake up and check status (track the beacon) in each time slot; b) non-tracking strategy: nodes only wake-up upon data arriving and stay awake till data transmitted to the coordinator. We consider the tradeoff between energy cost and average data transmission delay for both strategies. Both scenarios are formulated as optimization problems and the optimal solutions are discussed. Our results show that different data arrival rate and system parameters (such as contention access period interval, upstream speed etc.) result in different strategies in terms of energy optimization with maximum delay constraints. Hence, according to different applications and system settings, different strategies might be chosen by each node to achieve energy optimization for both self-interested view and system view. We give the relation among the tunable parameters by formulas and plots to illustrate which strategy is better under corresponding parameters. There are two main points emphasized in our results with delay constraints: on one hand, when the system setting is fixed by coordinator, nodes in the network can intelligently change their strategies according to corresponding application data arrival rate; on the other hand, when the nodes' applications are known by the coordinator, the coordinator can tune the system parameters to achieve optimal system energy consumption.

  10. MO-FG-BRA-06: Electromagnetic Beacon Insertion in Lung Cancer Patients and Resultant Surrogacy Errors for Dynamic MLC Tumour Tracking

    Hardcastle, N; Booth, J; Caillet, V; Haddad, C; Crasta, C [Royal North Shore Hospital, St. Leonards, NSW (Australia); O’Brien, R; Keall, P [University of Sydney, Sydney, NSW (Australia); Szymura, K [Royal North Shore Hospital, Sydney, NSW (Australia)

    2016-06-15

    Purpose: To assess endo-bronchial electromagnetic beacon insertion and to quantify the geometric accuracy of using beacons as a surrogate for tumour motion in real-time multileaf collimator (MLC) tracking of lung tumours. Methods: The LIGHT SABR trial is a world-first clinical trial in which the MLC leaves move with lung tumours in real time on a standard linear accelerator. Tracking is performed based on implanted electromagnetic beacons (CalypsoTM, Varian Medical Systems, USA) as a surrogate for tumour motion. Five patients have been treated and have each had three beacons implanted endo-bronchially under fluoroscopic guidance. The centre of mass (C.O.M) has been used to adapt the MLC in real-time. The geometric error in using the beacon C.O.M as a surrogate for tumour motion was measured by measuring the tumour and beacon C.O.M in all phases of the respiratory cycle of a 4DCT. The surrogacy error was defined as the difference in beacon and tumour C.O.M relative to the reference phase (maximum exhale). Results: All five patients have had three beacons successfully implanted with no migration between simulation and end of treatment. Beacon placement relative to tumour C.O.M varied from 14 to 74 mm and in one patient spanned two lobes. Surrogacy error was measured in each patient on the simulation 4DCT and ranged from 0 to 3 mm. Surrogacy error as measured on 4DCT was subject to artefacts in mid-ventilation phases. Surrogacy error was a function of breathing phase and was typically larger at maximum inhale. Conclusion: Beacon placement and thus surrogacy error is a major component of geometric uncertainty in MLC tracking of lung tumours. Surrogacy error must be measured on each patient and incorporated into margin calculation. Reduction of surrogacy error is limited by airway anatomy, however should be taken into consideration when performing beacon insertion and planning. This research is funded by Varian Medical Systems via a collaborative research agreement.

  11. MO-FG-BRA-06: Electromagnetic Beacon Insertion in Lung Cancer Patients and Resultant Surrogacy Errors for Dynamic MLC Tumour Tracking

    Hardcastle, N; Booth, J; Caillet, V; Haddad, C; Crasta, C; O’Brien, R; Keall, P; Szymura, K

    2016-01-01

    Purpose: To assess endo-bronchial electromagnetic beacon insertion and to quantify the geometric accuracy of using beacons as a surrogate for tumour motion in real-time multileaf collimator (MLC) tracking of lung tumours. Methods: The LIGHT SABR trial is a world-first clinical trial in which the MLC leaves move with lung tumours in real time on a standard linear accelerator. Tracking is performed based on implanted electromagnetic beacons (CalypsoTM, Varian Medical Systems, USA) as a surrogate for tumour motion. Five patients have been treated and have each had three beacons implanted endo-bronchially under fluoroscopic guidance. The centre of mass (C.O.M) has been used to adapt the MLC in real-time. The geometric error in using the beacon C.O.M as a surrogate for tumour motion was measured by measuring the tumour and beacon C.O.M in all phases of the respiratory cycle of a 4DCT. The surrogacy error was defined as the difference in beacon and tumour C.O.M relative to the reference phase (maximum exhale). Results: All five patients have had three beacons successfully implanted with no migration between simulation and end of treatment. Beacon placement relative to tumour C.O.M varied from 14 to 74 mm and in one patient spanned two lobes. Surrogacy error was measured in each patient on the simulation 4DCT and ranged from 0 to 3 mm. Surrogacy error as measured on 4DCT was subject to artefacts in mid-ventilation phases. Surrogacy error was a function of breathing phase and was typically larger at maximum inhale. Conclusion: Beacon placement and thus surrogacy error is a major component of geometric uncertainty in MLC tracking of lung tumours. Surrogacy error must be measured on each patient and incorporated into margin calculation. Reduction of surrogacy error is limited by airway anatomy, however should be taken into consideration when performing beacon insertion and planning. This research is funded by Varian Medical Systems via a collaborative research agreement.

  12. Penn State Radar Systems: Implementation and Observations

    Urbina, J. V.; Seal, R.; Sorbello, R.; Kuyeng, K.; Dyrud, L. P.

    2014-12-01

    Software Defined Radio/Radar (SDR) platforms have become increasingly popular as researchers, hobbyists, and military seek more efficient and cost-effective means for radar construction and operation. SDR platforms, by definition, utilize a software-based interface for configuration in contrast to traditional, hard-wired platforms. In an effort to provide new and improved radar sensing capabilities, Penn State has been developing advanced instruments and technologies for future radars, with primary objectives of making such instruments more capable, portable, and more cost effective. This paper will describe the design and implementation of two low-cost radar systems and their deployment in ionospheric research at both low and mid-latitudes. One radar has been installed near Penn State campus, University Park, Pennsylvania (77.97°W, 40.70°N), to make continuous meteor observations and mid-latitude plasma irregularities. The second radar is being installed in Huancayo (12.05°S, -75.33°E), Peru, which is capable of detecting E and F region plasma irregularities as well as meteor reflections. In this paper, we examine and compare the diurnal and seasonal variability of specular, non- specular, and head-echoes collected with these two new radar systems and discuss sampling biases of each meteor observation technique. We report our current efforts to validate and calibrate these radar systems with other VHF radars such as Jicamarca and SOUSY. We also present the general characteristics of continuous measurements of E-region and F-region coherent echoes using these modern radar systems and compare them with coherent radar events observed at other geographic mid-latitude radar stations.

  13. Radar observations of Comet Halley

    Campbell, D.B.; Harmon, J.K.; Shapiro, I.I.

    1989-01-01

    Five nights of Arecibo radar observations of Comet Halley are reported which reveal a feature in the overall average spectrum which, though weak, seems consistent with being an echo from the comet. The large radar cross section and large bandwidth of the feature suggest that the echo is predominantly from large grains which have been ejected from the nucleus. Extrapolation of the dust particle size distribution to large grain sizes gives a sufficient number of grains to account for the echo. The lack of a detectable echo from the nucleus, combined with estimates of its size and rotation rate from spacecraft encounters and other data, indicate that the nucleus has a surface of relatively high porosity. 33 references

  14. Terahertz radar cross section measurements.

    Iwaszczuk, Krzysztof; Heiselberg, Henning; Jepsen, Peter Uhd

    2010-12-06

    We perform angle- and frequency-resolved radar cross section (RCS) measurements on objects at terahertz frequencies. Our RCS measurements are performed on a scale model aircraft of size 5-10 cm in polar and azimuthal configurations, and correspond closely to RCS measurements with conventional radar on full-size objects. The measurements are performed in a terahertz time-domain system with freely propagating terahertz pulses generated by tilted pulse front excitation of lithium niobate crystals and measured with sub-picosecond time resolution. The application of a time domain system provides ranging information and also allows for identification of scattering points such as weaponry attached to the aircraft. The shapes of the models and positions of reflecting parts are retrieved by the filtered back projection algorithm.

  15. Radar Control Optimal Resource Allocation

    2015-07-13

    Dartmouth, Nova Scotia, Canada by the McMaster University Intelligent PIXel (IPIX) X-band Polarimetric Coherent Radar during the OHGR - Dartmouth...following coefficients [ q2, 4p22q, 12p12q, 12p11q, 12|P | ] (26) for A4 and [ q2, 4p22q, 4q(3 p12 + r22), 12(p11q + p22r22 − qr12), 12(|P |+ 2r22p12

  16. Radar channel balancing with commutation

    Doerry, Armin Walter

    2014-02-01

    When multiple channels are employed in a pulse-Doppler radar, achieving and maintaining balance between the channels is problematic. In some circumstances the channels may be commutated to achieve adequate balance. Commutation is the switching, trading, toggling, or multiplexing of the channels between signal paths. Commutation allows modulating the imbalance energy away from the balanced energy in Doppler, where it can be mitigated with filtering.

  17. Radar-based hail detection

    Skripniková, Kateřina; Řezáčová, Daniela

    2014-01-01

    Roč. 144, č. 1 (2014), s. 175-185 ISSN 0169-8095 R&D Projects: GA ČR(CZ) GAP209/11/2045; GA MŠk LD11044 Institutional support: RVO:68378289 Keywords : hail detection * weather radar * hail damage risk Subject RIV: DG - Athmosphere Sciences, Meteorology Impact factor: 2.844, year: 2014 http://www.sciencedirect.com/science/article/pii/S0169809513001804

  18. Radar-eddy current GPR

    A. O. Abramovych

    2014-01-01

    Introduction. At present there are many electrical schematic metal detectors (the most common kind of ground penetrating radar), which are differ in purpose. Each scheme has its own advantages and disadvantages compared to other schemes. Designing metal detector problem of optimal selection of functional units most schemes can only work with a narrow range of special purpose units. Functional units used in circuits can be replaced by better ones, but specialization schemes do not provide such...

  19. Detecting and classifying low probability of intercept radar

    Pace, Philip E

    2008-01-01

    This revised and expanded second edition brings you to the cutting edge with new chapters on LPI radar design, including over-the-horizon radar, random noise radar, and netted LPI radar. You also discover critical LPI detection techniques, parameter extraction signal processing techniques, and anti-radiation missile design strategies to counter LPI radar.

  20. Improving Weather Radar Precipitation Estimates by Combining two Types of Radars

    Nielsen, Jesper Ellerbæk; Thorndahl, Søren Liedtke; Rasmussen, Michael R.

    2014-01-01

    This paper presents a demonstration of how Local Area Weather Radar (LAWR) X-band measurements can be combined with meteorological C–band measurements into a single radar product. For this purpose, a blending method has been developed which combines the strengths of the two radar systems. Combining...... the two radar types achieves a radar product with both long range and high temporal resolution. It is validated that the blended radar product performs better than the individual radars based on ground observations from laser disdrometers. However, the data combination is challenged by lower performance...... of the LAWR. Although both radars benefits from the data combination, it is also found that advection based temporal interpolation is a more favourable method for increasing the temporal resolution of meteorological C–band measurements....

  1. Radar probing of the auroral plasma

    Brekke, A.

    1977-01-01

    The European Incoherent Scatter Radar in the Auroral Zone (EISCAT) is an intereuropean organization planning to install an incoherent scatter radar system in Northern Scandinavia. It is supported by Finland, France, Norway, Great Britain, Sweden and West Germany, and its headquarters is in Kiruna, Sweden. The radar is planned to be operating in 1979. In order to introduce students and young scientists to the incoherent scatter radar technique, a summer school was held in Tromsoe, from 5th to 13th June 1975. In these proceedings an introduction to the basic theory of fluctuations in a plasma is given. Some of the present incoherent scatter radars now in use are presented and special considerations with respect to the planned EISACT facility are discussed. Reviews of some recent results and scientific problems relevant to EISCAT are also presented and finally a presentation of some observational techniques complementary to incoherent scatter radars is included. (Ed.)

  2. The Comet Radar Explorer Mission

    Asphaug, Erik; Belton, Mike; Bockelee-Morvan, Dominique; Chesley, Steve; Delbo, Marco; Farnham, Tony; Gim, Yonggyu; Grimm, Robert; Herique, Alain; Kofman, Wlodek; Oberst, Juergen; Orosei, Roberto; Piqueux, Sylvain; Plaut, Jeff; Robinson, Mark; Sava, Paul; Heggy, Essam; Kurth, William; Scheeres, Dan; Denevi, Brett; Turtle, Elizabeth; Weissman, Paul

    2014-11-01

    Missions to cometary nuclei have revealed major geological surprises: (1) Global scale layers - do these persist through to the interior? Are they a record of primary accretion? (2) Smooth regions - are they landslides originating on the surface? Are they cryovolcanic? (3) Pits - are they impact craters or sublimation pits, or rooted in the interior? Unambiguous answers to these and other questions can be obtained by high definition 3D radar reflection imaging (RRI) of internal structure. RRI can answer many of the great unknowns in planetary science: How do primitive bodies accrete? Are cometary nuclei mostly ice? What drives their spectacular activity and evolution? The Comet Radar Explorer (CORE) mission will image the detailed internal structure of the nucleus of 10P/Tempel 2. This ~16 x 8 x 7 km Jupiter Family Comet (JFC), or its parent body, originated in the outer planets region possibly millions of years before planet formation. CORE arrives post-perihelion and observes the comet’s waning activity from safe distance. Once the nucleus is largely dormant, the spacecraft enters a ~20-km dedicated Radar Mapping Orbit (RMO). The exacting design of the RRI experiment and the precise navigation of RMO will achieve a highly focused 3D radar reflection image of internal structure, to tens of meters resolution, and tomographic images of velocity and attenuation to hundreds of meters resolution, tied to the gravity model and shape. Visible imagers will produce maps of the surface morphology, albedo, color, texture, and photometric response, and images for navigation and shape determination. The cameras will also monitor the structure and dynamics of the coma, and its dusty jets, allowing their correlation in 3D with deep interior structures and surface features. Repeated global high-resolution thermal images will probe the near-surface layers heated by the Sun. Derived maps of thermal inertia will be correlated with the radar boundary response, and photometry and

  3. Radar imaging of Saturn's rings

    Nicholson, Philip D.; French, Richard G.; Campbell, Donald B.; Margot, Jean-Luc; Nolan, Michael C.; Black, Gregory J.; Salo, Heikki J.

    2005-09-01

    We present delay-Doppler images of Saturn's rings based on radar observations made at Arecibo Observatory between 1999 and 2003, at a wavelength of 12.6 cm and at ring opening angles of 20.1°⩽|B|⩽26.7°. The average radar cross-section of the A ring is ˜77% relative to that of the B ring, while a stringent upper limit of 3% is placed on the cross-section of the C ring and 9% on that of the Cassini Division. These results are consistent with those obtained by Ostro et al. [1982, Icarus 49, 367-381] from radar observations at |B|=21.4°, but provide higher resolution maps of the rings' reflectivity profile. The average cross-section of the A and B rings, normalized by their projected unblocked area, is found to have decreased from 1.25±0.31 to 0.74±0.19 as the rings have opened up, while the circular polarization ratio has increased from 0.64±0.06 to 0.77±0.06. The steep decrease in cross-section is at variance with previous radar measurements [Ostro et al., 1980, Icarus 41, 381-388], and neither this nor the polarization variations are easily understood within the framework of either classical, many-particle-thick or monolayer ring models. One possible explanation involves vertical size segregation in the rings, whereby observations at larger elevation angles which see deeper into the rings preferentially see the larger particles concentrated near the rings' mid-plane. These larger particles may be less reflective and/or rougher and thus more depolarizing than the smaller ones. Images from all four years show a strong m=2 azimuthal asymmetry in the reflectivity of the A ring, with an amplitude of ±20% and minima at longitudes of 67±4° and 247±4° from the sub-Earth point. We attribute the asymmetry to the presence of gravitational wakes in the A ring as invoked by Colombo et al. [1976, Nature 264, 344-345] to explain the similar asymmetry long seen at optical wavelengths. A simple radiative transfer model suggests that the enhancement of the azimuthal

  4. Design of a K/Q-Band Beacon Receiver for the Alphasat Technology Demonstration Payload (TDP) #5 Experiment

    Morse, Jacquelynne R.

    2014-01-01

    This paper describes the design and performance of a coherent KQ-band (2040 GHz) beacon receiver developed at NASA Glenn Research Center (GRC) that will be installed at the Politecnico di Milano (POLIMI) for use in the Alphasat Technology Demonstration Payload 5 (TDP5) beacon experiment. The goal of this experiment is to characterize rain fade attenuation at 40 GHz to improve the performance of existing statistical rain attenuation models in the Q-band. The ground terminal developed by NASA GRC utilizes an FFT-based frequency estimation receiver capable of characterizing total path attenuation effects due to gaseous absorption, clouds, rain, and scintillation. The receiver system has been characterized in the lab and demonstrates a system dynamic range performance of better than 58 dB at 1 Hz and better than 48 dB at 10 Hz rates.

  5. Textural features for radar image analysis

    Shanmugan, K. S.; Narayanan, V.; Frost, V. S.; Stiles, J. A.; Holtzman, J. C.

    1981-01-01

    Texture is seen as an important spatial feature useful for identifying objects or regions of interest in an image. While textural features have been widely used in analyzing a variety of photographic images, they have not been used in processing radar images. A procedure for extracting a set of textural features for characterizing small areas in radar images is presented, and it is shown that these features can be used in classifying segments of radar images corresponding to different geological formations.

  6. Signal compression in radar using FPGA

    Escamilla Hemández, Enrique; Kravchenko, Víctor; Ponomaryov, Volodymyr; Duchen Sánchez, Gonzalo; Hernández Sánchez, David

    2010-01-01

    We present the hardware implementation of radar real time processing procedures using a simple, fast technique based on FPGA (Field Programmable Gate Array) architecture. This processing includes different window procedures during pulse compression in synthetic aperture radar (SAR). The radar signal compression processing is realized using matched filter, and classical and novel window functions, where we focus on better solution for minimum values of sidelobes. The proposed architecture expl...

  7. Pedestrian recognition using automotive radar sensors

    A. Bartsch; F. Fitzek; R. H. Rasshofer

    2012-01-01

    The application of modern series production automotive radar sensors to pedestrian recognition is an important topic in research on future driver assistance systems. The aim of this paper is to understand the potential and limits of such sensors in pedestrian recognition. This knowledge could be used to develop next generation radar sensors with improved pedestrian recognition capabilities. A new raw radar data signal processing algorithm is proposed that allows deep insight...

  8. Hardware Implementation of A Non-RLL Soft-decoding Beacon-based Visible Light Communication Receiver

    Nguyen, Duc-Phuc; Le, Dinh-Dung; Tran, Thi-Hong; Huynh, Huu-Thuan; Nakashima, Yasuhiko

    2018-01-01

    Visible light communication (VLC)-based beacon systems, which usually transmit identification (ID) information in small-size data frames are applied widely in indoor localization applications. There is one fact that flicker of LED light should be avoid in any VLC systems. Current flicker mitigation solutions based on run-length limited (RLL) codes suffer from reduced code rates, or are limited to hard-decoding forward error correction (FEC) decoders. Recently, soft-decoding techniques of RLL-...

  9. Radar reflection off extensive air showers

    Werner F.

    2013-06-01

    Full Text Available We investigate the possibility of detecting extensive air showers by the radar technique. Considering a bistatic radar system and different shower geometries, we simulate reflection of radio waves off the static plasma produced by the shower in the air. Using the Thomson cross-section for radio wave reflection, we obtain the time evolution of the signal received by the antennas. The frequency upshift of the radar echo and the power received are studied to verify the feasibility of the radar detection technique.

  10. A case study of pediatric asthma alerts from the beacon community program in cincinnati: technology is just the first step.

    Trudnak, Tara; Mansour, Mona; Mandel, Keith; Sauers, Hadley; Pandzik, Gerry; Donisi, Carl; Fairbrother, Gerry

    2014-01-01

    The Beacon Community in Cincinnati, Ohio was an innovative, community-wide initiative to use technology to transform care. One important feature was the development of regional alerts to notify practices when patients were hospitalized or seen in the emergency department. The purpose of this paper is to describe the way in which technology engages the improvement process, and to describe the early stages of learning how to use technology to enhance quality improvement. We interviewed key Beacon leaders as well as providers and office staff in selected practices. We also collected preliminary data from practices that reflected handling of alerts, including the number of asthma related alerts received and followed up. Regional alerts, supplied by the community-wide health information exchange, were a significant addition to the quality improvement effort in that they enabled practices to identify and follow up with additional children at risk. An important finding was the substantial effort at the practice level to integrate technology into ongoing patient care. Developing the technology for community wide alerts represented a significant endeavor in the Cincinnati Beacon Community. However, the technology was just the first step. Despite extra effort and time required on the part of individual practices, they reported that the value of having alerts was high. Hospital and ED visits represent some of the most costly aspects of care, and an efficient process for intervening with children using these costly services was seen as of significant value.

  11. Radar network communication through sensing of frequency hopping

    Dowla, Farid; Nekoogar, Faranak

    2013-05-28

    In one embodiment, a radar communication system includes a plurality of radars having a communication range and being capable of operating at a sensing frequency and a reporting frequency, wherein the reporting frequency is different than the sensing frequency, each radar is adapted for operating at the sensing frequency until an event is detected, each radar in the plurality of radars has an identification/location frequency for reporting information different from the sensing frequency, a first radar of the radars which senses the event sends a reporting frequency corresponding to its identification/location frequency when the event is detected, and all other radars in the plurality of radars switch their reporting frequencies to match the reporting frequency of the first radar upon detecting the reporting frequency switch of a radar within the communication range. In another embodiment, a method is presented for communicating information in a radar system.

  12. The NASA radar entomology program at Wallops Flight Center

    Vaughn, C. R.

    1979-01-01

    NASA contribution to radar entomology is presented. Wallops Flight Center is described in terms of its radar systems. Radar tracking of birds and insects was recorded from helicopters for airspeed and vertical speed.

  13. Method for radar detection of persons wearing wires

    Fox, William P.

    2014-01-01

    8,730,098 B1 Methods are described for radar detection of persons wearing wires using radar spectra data including the vertical polarization (VV) radar cross section and the horizontal polarization (HH) radar cross section for a person. In one embodiment, the ratio of the vertical polarization (VV) radar cross section to the horizontal polarization (HH) radar cross section for a person is compared to a detection threshold to determine whether the person is wearing wire...

  14. First observations of large-scale wave structure and equatorial spread F using CERTO radio beacon on the C/NOFS satellite

    Thampi, S.; Yamamoto, M.; Tsunoda, R. T.; Otsuka, Y.; Tsugawa, T.; Uemoto, J.; Ishii, M.

    2009-12-01

    Equatorial spread F (ESF) is a generic name, which refers to the presence of a wide spectrum of field-aligned irregularities in the equatorial nighttime F-region that can extend over nearly seven orders of magnitude. Recently, a large-scale wave structure (LSWS) in the F-layer electron density is identified as a reliable precursor to ESF. The LSWS can be identified as a quasi-periodic modulation in the altitude of isoelectron density contours in the bottomside F-region, superimposed on a mean slope that increases in altitude from west to east. First observations of large-scale wave structure (LSWS) and the subsequent development of equatorial spread F (ESF), using total electron content (TEC) derived from the ground based reception of Coherent Electromagnetic Radio Tomography (CETRO) radio beacon signals on board the C/NOFS (Communications/Navigation Outage Forecasting System) satellite will be presented. For this study the TEC observations from Bac Lieu, Vietnam (9.2°N, 105.6°E geographic, 1.7°N magnetic dip latitude), Phukhet (7.8°N, 98.38°E, 0.4°S dip lat) and Kototabang, Indonesia (0.20°S, 100.32°E, 10.36°S dip lat) are analyzed along with ionosonde observations from Bac Lieu, Chumphon (10.7°N, 99.4°E, 3.3° dip lat) and 30.8 MHz VHF radar observations from Kototabang. It should also be mentioned here that LSWS is not easily detectable with overhead measurements using a sensor at a fixed location, at least not during its early growth phase, mainly because initially it grows in amplitude without significant zonal drift. The results indicate (1) LSWS appears to play a more important role in the development of ESF than the post-sunset rise (PSSR) of the F-layer, and (2) LSWS can appear well before E-region sunset. Other findings, that LSWS does not have significant zonal drift in the initial stages of growth, and can have zonal wavelengths of several hundred kilometers, corroborate earlier reports.

  15. The KUT meteor radar: An educational low cost meteor observation system by radio forward scattering

    Madkour, W.; Yamamoto, M.

    2016-01-01

    The Kochi University of Technology (KUT) meteor radar is an educational low cost observation system built at Kochi, Japan by successive graduate students since 2004. The system takes advantage of the continuous VHF- band beacon signal emitted from Fukui National College of Technology (FNCT) for scientific usage all over Japan by receiving the forward scattered signals. The system uses the classical forward scattering setup similar to the setup described by the international meteor organization (IMO), gradually developed from the most basic single antenna setup to the multi-site meteor path determination setup. The primary objective is to automate the observation of the meteor parameters continuously to provide amounts of data sufficient for statistical analysis. The developed software system automates the observation of the astronomical meteor parameters such as meteor direction, velocity and trajectory. Also, automated counting of meteor echoes and their durations are used to observe mesospheric ozone concentration by analyzing the duration distribution of different meteor showers. The meteor parameters observed and the methodology used for each are briefly summarized.

  16. Full Polarimetric Synthetic Aperture Radar (SAR) Data for ionosphere observation - A comparative study

    Mohanty, S.; Singh, G.

    2017-12-01

    Ionosphere, predominantly, govern the propagation of radio waves, especially at L-band and lower frequencies. Small-scale, rapid fluctuations in the electron density, termed as scintillation phenomenon, cause rapid variations in signal amplitude and phase. Scintillation studies have been done using ground-based radio transmitter and beacon GPS signals. In this work, attempt has been made to utilize full polarimetric synthetic aperture radar (SAR) satellite signal at L-band (1.27 GHz) to develop a new measurement index for SAR signal intensity fluctuation. Datasets acquired from Japan's latest Advanced Land Observation Satellite (ALOS)-2 over the Indian subcontinent on two different dates, with varying ionospheric activities, have been utilized to compare the index. A 20% increase in the index values for a scintillation-affected day has been observed. The result coincides with the nature of ionospheric scintillation pattern typically observed over the equatorial belt. Total electron content values, for the two dates of acquisition, obtained from freely available Ionosphere Exchange (IONEX) data have been used to validate the varying ionospheric activities as well as the trend in index results. Another interesting finding of the paper is the demarcation of the equatorial anomaly belt. The index values are comparatively higher at these latitudes on a scintillation-affected day. Furthermore, the SAR signal intensity fluctuation index has great potential in being used as a preliminary measurement index to identify low frequency SAR data affected by ionospheric scintillation.

  17. A quantum dot-aptamer beacon using a DNA intercalating dye as the FRET reporter: application to label-free thrombin detection.

    Chi, Chun-Wei; Lao, Yeh-Hsing; Li, Yi-Shan; Chen, Lin-Chi

    2011-03-15

    A new quantum dot (QD)-aptamer (apt) beacon that acts by folding-induced dissociation of a DNA intercalating dye, BOBO-3(B), is demonstrated with label-free thrombin detection. The beacon, denoted as QD-apt:B, is constructed by (1) coupling of a single-stranded thrombin aptamer to Qdot 565 via EDC/Sulfo-NHS chemistry and (2) staining the duplex regions of the aptamer on QD with excess BOBO-3 before thrombin binding. When mixing a thrombin sample with QD-apt:B, BOBO-3 is competed away from the beacon due to target-induced aptamer folding, which then causes a decrease in QD fluorescence resonance energy transfer (FRET)-mediated BOBO-3 emission and achieves thrombin quantitation. In this work, the effects of Mg(2+), coupling time, and aptamer type on the beacon's performances are investigated and discussed thoroughly with various methods, including transmission electron microscopy (TEM), dynamic light scattering (DLS), and two-color differential gel electrophoresis. Using the best aptamer beacon (HTQ37), we attain highly specific and wide-range detection (from nM to μM) of thrombin in buffer, and the beacon can sense nM-range thrombin in 15% diluted serum. Compared to the reported QD aptamer assays, our method is advantageous from the aspect of using a simple sensory unit design without losing the detection sensitivity. Therefore, we consider the QD-apt:B beacon a potential alternative to immuno-reagents and an effective tool to study nucleic acid folding on QD as well. Copyright © 2011 Elsevier B.V. All rights reserved.

  18. Array-Based Ultrawideband through-Wall Radar: Prediction and Assessment of Real Radar Abilities

    Nadia Maaref

    2013-01-01

    Full Text Available This paper deals with a new through-the-wall (TTW radar demonstrator for the detection and the localisation of people in a room (in a noncooperative way with the radar situated outside but in the vicinity of the first wall. After modelling the propagation through various walls and quantifying the backscattering by the human body, an analysis of the technical considerations which aims at defining the radar design is presented. Finally, an ultrawideband (UWB frequency modulated continuous wave (FMCW radar is proposed, designed, and implemented. Some representative trials show that this radar is able to localise and track moving people behind a wall in real time.

  19. Pocket radar guide key facts, equations, and data

    Curry, G Richard

    2010-01-01

    ThePocket Radar Guideis a concise collection of key radar facts and important radar data that provides you with necessary radar information when you are away from your office or references. It includes statements and comments on radar design, operation, and performance; equations describing the characteristics and performance of radar systems and their components; and tables with data on radar characteristics and key performance issues.It is intended to supplement other radar information sources by providing a pocket companion to refresh memory and provide details whenever you need them such a

  20. Customizable Digital Receivers for Radar

    Moller, Delwyn; Heavey, Brandon; Sadowy, Gregory

    2008-01-01

    Compact, highly customizable digital receivers are being developed for the system described in 'Radar Interferometer for Topographic Mapping of Glaciers and Ice Sheets' (NPO-43962), NASA Tech Briefs, Vol. 31, No. 7 (August 2007), page 72. The receivers are required to operate in unison, sampling radar returns received by the antenna elements in a digital beam-forming (DBF) mode. The design of these receivers could also be adapted to commercial radar systems. At the time of reporting the information for this article, there were no commercially available digital receivers capable of satisfying all of the operational requirements and compact enough to be mounted directly on the antenna elements. A provided figure depicts the overall system of which the digital receivers are parts. Each digital receiver includes an analog-to-digital converter (ADC), a demultiplexer (DMUX), and a field-programmable gate array (FPGA). The ADC effects 10-bit band-pass sampling of input signals having frequencies up to 3.5 GHz. The input samples are demultiplexed at a user-selectable rate of 1:2 or 1:4, then buffered in part of the FPGA that functions as a first-in/first-out (FIFO) memory. Another part of the FPGA serves as a controller for the ADC, DMUX, and FIFO memory and as an interface between (1) the rest of the receiver and (2) a front-panel data port (FPDP) bus, which is an industry-standard parallel data bus that has a high data-rate capability and multichannel configuration suitable for DBF. Still other parts of the FPGA in each receiver perform signal-processing functions. The digital receivers can be configured to operate in a stand-alone mode, or in a multichannel mode as needed for DBF. The customizability of the receiver makes it applicable to a broad range of system architectures. The capability for operation of receivers in either a stand-alone or a DBF mode enables the use of the receivers in an unprecedentedly wide variety of radar systems.

  1. Visual Attention to Radar Displays

    Moray, N.; Richards, M.; Brophy, C.

    1984-01-01

    A model is described which predicts the allocation of attention to the features of a radar display. It uses the growth of uncertainty and the probability of near collision to call the eye to a feature of the display. The main source of uncertainty is forgetting following a fixation, which is modelled as a two dimensional diffusion process. The model was used to predict information overload in intercept controllers, and preliminary validation obtained by recording eye movements of intercept controllers in simulated and live (practice) interception.

  2. Radar Methods in Urban Environments

    2016-10-26

    and A. Nehorai, "A low-complexity multi-target tracking algorithm in urban environments using sparse modeling ,’’ Signal Processing, Vol. 92, pp. 2199...AFRL-AFOSR-VA-TR-2016-0344 Radar Methods in Urban Environments Arye Nehorai WASHINGTON UNIVERSITY THE Final Report 10/26/2016 DISTRIBUTION A...of information   if it does not display a currently valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ORGANIZATION . 1. REPORT DATE

  3. Ultra-wideband radar sensors and networks

    Leach, Jr., Richard R; Nekoogar, Faranak; Haugen, Peter C

    2013-08-06

    Ultra wideband radar motion sensors strategically placed in an area of interest communicate with a wireless ad hoc network to provide remote area surveillance. Swept range impulse radar and a heart and respiration monitor combined with the motion sensor further improves discrimination.

  4. Weather radar rainfall data in urban hydrology

    Thorndahl, Søren; Einfalt, Thomas; Willems, Patrick; Ellerbæk Nielsen, Jesper; ten Veldhuis, J.A.E.; Arnbjerg-Nielsen, Karsten; Rasmussen, Michael R.; Molnar, Peter

    2017-01-01

    Application of weather radar data in urban hydrological applications has evolved significantly during the past decade as an alternative to traditional rainfall observations with rain gauges. Advances in radar hardware, data processing, numerical models, and emerging fields within urban hydrology

  5. High-precision positioning of radar scatterers

    Dheenathayalan, P.; Small, D.; Schubert, A.; Hanssen, R.F.

    2016-01-01

    Remote sensing radar satellites cover wide areas and provide spatially dense measurements, with millions of scatterers. Knowledge of the precise position of each radar scatterer is essential to identify the corresponding object and interpret the estimated deformation. The absolute position accuracy

  6. A Scanning Microwave Radar and Radiometer

    Skou, Niels

    1995-01-01

    The Scanning Microwave Radar and Radiometer (SMRR) is a line scanner featuring a combined radar and radiometer system operating around 35 and 94 GHz. The layout of the SMRR is shown. The 2 offset antenna parabolas scan in synchronism, the receiver antenna has the highest gain in order to ensure...

  7. Incidence angle normalization of radar backscatter data

    NASA’s Soil Moisture Passive Active (SMAP) satellite (~2014) will include a radar system that will provide L-band multi-polarization backscatter at a constant incidence angle of 40º. During the pre-launch phase of the project there is a need for observations that will support the radar-based soil mo...

  8. Synthetic aperture radar: principles and applications

    Khan, N.A.; Yahya, K.M.

    2003-01-01

    In this paper an introduction to synthetic aperture radar is presented. Synthetic aperture radar is a relatively new remote sensing platform and the technology has matured a lot in the last two decades. This paper introduces the concepts behind SAR principles as well as the major areas where this new technology has shown additional information. (author)

  9. Wind energy applications of synthetic aperture radar

    Badger, Merete

    Synthetic aperture radars (SAR), mounted on satellites or aircraft, have proven useful for ocean wind mapping. Wind speeds at the height 10 m may be retrieved from measurements of radar backscatter using empirical model functions. The resulting windfields are valuable in offshore wind energy plan...

  10. Classification of Agricultural Crops in Radar Images

    Hoogeboom, P.

    1983-01-01

    For the past few years an accurate X-band SLAR system with digital recording has been available in The Netherlands. The images of this system are corrected to indicate radar backscatter coefficients (gamma) instead of arbitrary greytones. In 1980 a radar measurement campaign was organized in the

  11. Classification of radar echoes using fractal geometry

    Azzaz, Nafissa; Haddad, Boualem

    2017-01-01

    Highlights: • Implementation of two concepts of fractal geometry to classify two types of meteorological radar echoes. • A new approach, called a multi-scale fractal dimension is used for classification between fixed echoes and rain echoes. • An Automatic identification system of meteorological radar echoes was proposed using fractal geometry. - Abstract: This paper deals with the discrimination between the precipitation echoes and the ground echoes in meteorological radar images using fractal geometry. This study aims to improve the measurement of precipitations by weather radars. For this, we considered three radar sites: Bordeaux (France), Dakar (Senegal) and Me lbourne (USA). We showed that the fractal dimension based on contourlet and the fractal lacunarity are pertinent to discriminate between ground and precipitation echoes. We also demonstrated that the ground echoes have a multifractal structure but the precipitations are more homogeneous than ground echoes whatever the prevailing climate. Thereby, we developed an automatic classification system of radar using a graphic interface. This interface, based on the fractal geometry makes possible the identification of radar echoes type in real time. This system can be inserted in weather radar for the improvement of precipitation estimations.

  12. Millimeter wave radars raise weapon IQ

    Lerner, E. J.

    1985-02-01

    The problems encountered by laser and IR homing devices for guided munitions may be tractable with warhead-mounted mm-wave radars. Operating at about 100 GHz and having several kilometers range, mm-wave radars see through darkness, fog, rain and smoke. The radar must be coupled with an analyzer that discerns moving and stationary targets and higher priority targets. The target lock-on can include shut-off of the transmitter and reception of naturally-generated mm-waves bouncing off the target when in the terminal phase of the flight. Monopulse transmitters have simplified the radar design, although mass production of finline small radar units has yet to be accomplished, particularly in combining GaAs, ferrites and other materials on one monolithic chip.

  13. Weather radar rainfall data in urban hydrology

    Thorndahl, Søren; Einfalt, Thomas; Willems, Patrick

    2017-01-01

    Application of weather radar data in urban hydrological applications has evolved significantly during the past decade as an alternative to traditional rainfall observations with rain gauges. Advances in radar hardware, data processing, numerical models, and emerging fields within urban hydrology...... necessitate an updated review of the state of the art in such radar rainfall data and applications. Three key areas with significant advances over the past decade have been identified: (1) temporal and spatial resolution of rainfall data required for different types of hydrological applications, (2) rainfall...... estimation, radar data adjustment and data quality, and (3) nowcasting of radar rainfall and real-time applications. Based on these three fields of research, the paper provides recommendations based on an updated overview of shortcomings, gains, and novel developments in relation to urban hydrological...

  14. Weather radar rainfall data in urban hydrology

    Thorndahl, Søren; Einfalt, Thomas; Willems, Patrick

    2017-01-01

    estimation, radar data adjustment and data quality, and (3) nowcasting of radar rainfall and real-time applications. Based on these three fields of research, the paper provides recommendations based on an updated overview of shortcomings, gains, and novel developments in relation to urban hydrological...... applications. The paper also reviews how the focus in urban hydrology research has shifted over the last decade to fields such as climate change impacts, resilience of urban areas to hydrological extremes, and online prediction/warning systems. It is discussed how radar rainfall data can add value......Application of weather radar data in urban hydrological applications has evolved significantly during the past decade as an alternative to traditional rainfall observations with rain gauges. Advances in radar hardware, data processing, numerical models, and emerging fields within urban hydrology...

  15. Remote sensing with laser spectrum radar

    Wang, Tianhe; Zhou, Tao; Jia, Xiaodong

    2016-10-01

    The unmanned airborne (UAV) laser spectrum radar has played a leading role in remote sensing because the transmitter and the receiver are together at laser spectrum radar. The advantages of the integrated transceiver laser spectrum radar is that it can be used in the oil and gas pipeline leak detection patrol line which needs the non-contact reflective detection. The UAV laser spectrum radar can patrol the line and specially detect the swept the area are now in no man's land because most of the oil and gas pipelines are in no man's land. It can save labor costs compared to the manned aircraft and ensure the safety of the pilots. The UAV laser spectrum radar can be also applied in the post disaster relief which detects the gas composition before the firefighters entering the scene of the rescue.

  16. Meteor observation by the Kyoto meteor radar

    Kato, S.; Tsuda, T.

    1987-01-01

    The Kyoto Meteor Radar is a monostatic coherent pulsed Doppler radar operating on the frequency of 31.57 MH. The system is computer controlled and uses radio interferometry for echo height determination. The antenna, an improvement, can be directed either to the north or the east. The system has been continuously collecting data on winds at meteor heights by radar observation. The meteor echo rate was also measured, the echo rate distribution with height and the daily variation in height integrated echo rate are discussed. Investigations of atmospheric tides are being pursued by cooperative observations. A novel approach to the study of gravity waves was attempted using the meteor radar which is able to detect the horizontal propagation of the waves by observing the changing phase through the region illuminated by the radar

  17. Space Weather Operation at KASI With Van Allen Probes Beacon Signals

    Lee, Jongkil; Kim, Kyung-Chan; Giuseppe, Romeo; Ukhorskiy, Sasha; Sibeck, David; Kessel, Ramona; Mauk, Barry; Giles, Barbara; Gu, Bon-Jun; Lee, Hyesook; Park, Young-Deuk; Lee, Jaejin

    2018-02-01

    The Van Allen Probes (VAPs) are the only modern National Aeronautics and Space Administration (NASA) spacecraft broadcasting real-time data on the Earth's radiation belts for space weather operations. Since 2012, the Korea Astronomy and Space Science Institute (KASI) has contributed to the receipt of these data via a 7 m satellite-tracking antenna and used these beacon data for space weather operations. An approximately 15 min period is required from measurement to acquisition of Level-1 data. In this paper, we demonstrate the use of VAP data for monitoring space weather conditions at geostationary orbit (GEO) by highlighting the Saint Patrick's Day storm of 2015. During that storm, Probe-A observed a significant increase in the relativistic electron flux at 3 RE. Those electrons diffused outward resulting in a large increase of the electron flux >2 MeV at GEO, which potentially threatened satellite operations. Based on this study, we conclude that the combination of VAP data and National Oceanic and Atmospheric Administration-Geostationary Operational Environmental Satellite (NOAA-GOES) data can provide improved space environment information to geostationary satellite operators. In addition, the findings obtained indicate that more data-receiving sites would be necessary and data connections improved if this or a similar system were to be used as an operational data service.

  18. The Inversion of Ionospheric/plasmaspheric Electron Density From GPS Beacon Observations

    Zou, Y. H.; Xu, J. S.; Ma, S. Y.

    It is a space-time 4-D tomography to reconstruct ionospheric/ plasmaspheric elec- tron density, Ne, from ground-based GPS beacon measurements. The mathematical foundation of such inversion is studied in this paper and some simulation results of reconstruction for GPS network observation are presented. Assuming reasonably a power law dependence of NE on time with an index number of 1-3 during one ob- servational time of GPS (60-90min.), 4-D inversion in consideration is reduced to a 3-D cone-beam tomography with incomplete projections. To see clearly the effects of the incompleteness on the quality of reconstruction for 3-D condition, we deduced theoretically the formulae of 3-D parallel-beam tomography. After establishing the mathematical basis, we adopt linear temporal dependence of NE and voxel elemental functions to perform simulation of NE reconstruction with the help of IRI90 model. Reasonable time-dependent 3-D images of ionosphere/ plasmasphere electron density distributions are obtained when taking proper layout of the GPS network and allowing variable resolutions in vertical.

  19. A molecular beacon microarray based on a quantum dot label for detecting single nucleotide polymorphisms.

    Guo, Qingsheng; Bai, Zhixiong; Liu, Yuqian; Sun, Qingjiang

    2016-03-15

    In this work, we report the application of streptavidin-coated quantum dot (strAV-QD) in molecular beacon (MB) microarray assays by using the strAV-QD to label the immobilized MB, avoiding target labeling and meanwhile obviating the use of amplification. The MBs are stem-loop structured oligodeoxynucleotides, modified with a thiol and a biotin at two terminals of the stem. With the strAV-QD labeling an "opened" MB rather than a "closed" MB via streptavidin-biotin reaction, a sensitive and specific detection of label-free target DNA sequence is demonstrated by the MB microarray, with a signal-to-background ratio of 8. The immobilized MBs can be perfectly regenerated, allowing the reuse of the microarray. The MB microarray also is able to detect single nucleotide polymorphisms, exhibiting genotype-dependent fluorescence signals. It is demonstrated that the MB microarray can perform as a 4-to-2 encoder, compressing the genotype information into two outputs. Copyright © 2015 Elsevier B.V. All rights reserved.

  20. Learning from Health Information Exchange Technical Architecture and Implementation in Seven Beacon Communities

    McCarthy, Douglas B.; Propp, Karen; Cohen, Alexander; Sabharwal, Raj; Schachter, Abigail A.; Rein, Alison L.

    2014-01-01

    As health care providers adopt and make “meaningful use” of health information technology (health IT), communities and delivery systems must set up the infrastructure to facilitate health information exchange (HIE) between providers and numerous other stakeholders who have a role in supporting health and care. By facilitating better communication and coordination between providers, HIE has the potential to improve clinical decision-making and continuity of care, while reducing unnecessary use of services. When implemented as part of a broader strategy for health care delivery system and payment reform, HIE capability also can enable the use of analytic tools needed for population health management, patient engagement in care, and continuous learning and improvement. The diverse experiences of seven communities that participated in the three-year federal Beacon Community Program offer practical insight into factors influencing the technical architecture of exchange infrastructure and its role in supporting improved care, reduced cost, and a healthier population. The case studies also document challenges faced by the communities, such as significant time and resources required to harmonize variations in the interpretation of data standards. Findings indicate that their progress developing community-based HIE strategies, while driven by local needs and objectives, is also influenced by broader legal, policy, and market conditions. PMID:25848591

  1. The Keys to Governance and Stakeholder Engagement: The Southeast Michigan Beacon Community Case Study

    Des Jardins, Terrisca R.

    2014-01-01

    Community-based health information exchanges (HIEs) and efforts to consolidate and house data are growing, given the advent of Accountable Care Organizations (ACOs) under the Affordable Care Act and other similar population health focused initiatives. The Southeast Michigan Beacon Community (SEMBC) can be looked to as one case study that offers lessons learned, insights on challenges faced and accompanying workarounds related to governance and stakeholder engagement. The SEMBC case study employs an established Data Warehouse Governance Framework to identify and explain the necessary governance and stakeholder engagement components, particularly as they relate to community-wide data sharing and data warehouses or repositories. Perhaps the biggest lesson learned through the SEMBC experience is that community-based work is hard. It requires a great deal of community leadership, collaboration and resources. SEMBC found that organizational structure and guiding principles needed to be continually revisited and nurtured in order to build the relationships and trust needed among stakeholder organizations. SEMBC also found that risks and risk mitigation tactics presented challenges and opportunities at the outset and through the duration of the three year pilot period. Other communities across the country embarking on similar efforts need to consider realistic expectations about community data sharing infrastructures and the accompanying and necessary governance and stakeholder engagement fundamentals. PMID:25848612

  2. Theranostic properties of a survivin-directed molecular beacon in human melanoma cells.

    Sara Carpi

    Full Text Available Survivin is an inhibitor of apoptosis overexpressed in different types of tumors and undetectable in most terminally differentiated normal tissues. In the current study, we sought to evaluate the in vitro theranostic properties of a molecular beacon-oligodeoxynucleotide (MB that targets survivin mRNA. We used laser scanning confocal microscopy to study MB delivery in living cells and real-time PCR and western blot to assess selective survivin-targeting in human malignant melanoma cells. We further assess the pro-apoptotic effect of MB by measuring internucleosomal DNA fragmentation, dissipation of mitochondrial membrane potential (MMP and changes in nuclear morphology. Transfection of MB into A375 and 501 Mel cells generated high signal intensity from the cytoplasm, while no signal was detected in the extracellular environment and in survivin-negative cells (i.e., human melanocytes and monocytes. MB time dependently decreased survivin mRNA and protein expression in melanoma cells with the maximum effect reached at 72 h. Treatment of melanoma cells with MB induced apoptosis by significant changes in MMP, accumulation of histone-complexed DNA fragments in the cytoplasm and nuclear condensation. MB also enhanced the pro-apoptotic effect of standard chemotherapeutic drugs tested at clinically relevant concentrations. The MB tested in the current study conjugates the ability of imaging with the pharmacological silencing activity against survivin mRNA in human melanoma cells and may represent an innovative approach for cancer diagnosis and treatment.

  3. Modified beacon probe assisted dual signal amplification for visual detection of microRNA.

    Sun, Xiuwei; Ying, Na; Ju, Chuanjing; Li, Zhongyi; Xu, Na; Qu, Guijuan; Liu, Wensen; Wan, Jiayu

    2018-04-21

    In a recent study, we reported a novel assay for the detection of microRNA-21 based on duplex-specific nuclease (DSN)-assisted isothermal cleavage and hybridization chain reaction (HCR) dual signal amplification. The Fam modified double-stranded DNA products were generated after the HCR, another biotin modified probe was digested by DSN and released from the magnetic beads after the addition of the target miRNA. The released sequence was then combined with HCR products to form a double-tagging dsDNA, which can be recognized by the lateral flow strips. In this study, we introduced a 2-OMethyl-RNA modified beacon probe (2-OMe-MB) to make some improvements based on the previous study. Firstly, the substitution of modified probe combined on magnetic beads avoids the fussy washing steps for the separation of un-reacted probes. Furthermore, the modification of 2-OMe on the stem of the probe avoided the unnecessary cleavage by DSN, which greatly reduce the background signal. Compared to the previous work, these improvements save us a lot of steps but possess the comparable sensitivity and selectivity. Copyright © 2018 Elsevier Inc. All rights reserved.

  4. Observations of inner plasmasphere irregularities with a satellite-beacon radio-interferometer array

    Jacobson, A.R.; Hoogeveen, G.; Carlos, R.C.; Wu, G.; Fejer, B.G.; Kelley, M.C.

    1996-01-01

    A radio-interferometer array illuminated by 136-MHz beacons of several geosynchronous satellites has been used to study small (≥10 13 m -2 ) transient disturbances in the total electron content along the lines of sight to the satellites. High-frequency (f>3 mHz) electron content oscillations are persistently observed, particularly during night and particularly during geomagnetically disturbed periods. The oscillations move across the array plane at speeds in the range 200 endash 2000 m/s, with propagation azimuths that are strongly peaked in lobes toward the western half-plane. Detailed analysis of this azimuth behavior, involving comparison between observations on various satellite positions, indicates compellingly that the phase oscillations originate in radio refraction due to geomagnetically aligned plasma density perturbations in the inner plasmasphere. The motion of the phase perturbations across the array plane is caused by EXB drift of the plasma medium in which the irregularities are embedded. We review the statistics of 2.5 years of around-the-clock data on the local time, magnetic disturbance, seasonal, and line-of-sight variations of these observed irregularities. We compare the irregularities close-quote inferred electrodynamic drifts to what is known about midlatitude plasma drift from incoherent scatter. Finally, we show in detail how the observation of these irregularities provides a unique and complementary monitor of inner plasmasphere irregularity incidence and zonal drift.copyright 1996 American Geophysical Union

  5. Outage Probability Analysis in Power-Beacon Assisted Energy Harvesting Cognitive Relay Wireless Networks

    Ngoc Phuc Le

    2017-01-01

    Full Text Available We study the performance of the secondary relay system in a power-beacon (PB assisted energy harvesting cognitive relay wireless network. In our system model, a secondary source node and a relay node first harvest energy from distributed PBs. Then, the source node transmits its data to the destination node with the help of the relay node. Also, fading coefficients of the links from the PBs to the source node and relay node are assumed independent but not necessarily identically distributed (i.n.i.d Nakagami-m random variables. We derive exact expressions for the power outage probability and the channel outage probability. Based on that, we analyze the total outage probability of the secondary relay system. Asymptotic analysis is also performed, which provides insights into the system behavior. Moreover, we evaluate impacts of the primary network on the performance of the secondary network with respect to the tolerant interference threshold at the primary receiver as well as the interference introduced by the primary transmitter at the secondary source and relay nodes. Simulation results are provided to validate the analysis.

  6. Recognition of dual targets by a molecular beacon-based sensor: subtyping of influenza A virus.

    Lee, Chun-Ching; Liao, Yu-Chieh; Lai, Yu-Hsuan; Lee, Chang-Chun David; Chuang, Min-Chieh

    2015-01-01

    A molecular beacon (MB)-based sensor to offer a decisive answer in combination with information originated from dual-target inputs is designed. The system harnesses an assistant strand and thermodynamically favored designation of unpaired nucleotides (UNs) to process the binary targets in "AND-gate" format and report fluorescence in "off-on" mechanism via a formation of a DNA four-way junction (4WJ). By manipulating composition of the UNs, the dynamic fluorescence difference between the binary targets-coexisting circumstance and any other scenario was maximized. Characteristic equilibrium constant (K), change of entropy (ΔS), and association rate constant (k) between the association ("on") and dissociation ("off") states of the 4WJ were evaluated to understand unfolding behavior of MB in connection to its sensing capability. Favorable MB and UNs were furthermore designed toward analysis of genuine genetic sequences of hemagglutinin (HA) and neuraminidase (NA) in an influenza A H5N2 isolate. The MB-based sensor was demonstrated to yield a linear calibration range from 1.2 to 240 nM and detection limit of 120 pM. Furthermore, high-fidelity subtyping of influenza virus was implemented in a sample of unpurified amplicons. The strategy opens an alternative avenue of MB-based sensors for dual targets toward applications in clinical diagnosis.

  7. Learning from health information exchange technical architecture and implementation in seven beacon communities.

    McCarthy, Douglas B; Propp, Karen; Cohen, Alexander; Sabharwal, Raj; Schachter, Abigail A; Rein, Alison L

    2014-01-01

    As health care providers adopt and make "meaningful use" of health information technology (health IT), communities and delivery systems must set up the infrastructure to facilitate health information exchange (HIE) between providers and numerous other stakeholders who have a role in supporting health and care. By facilitating better communication and coordination between providers, HIE has the potential to improve clinical decision-making and continuity of care, while reducing unnecessary use of services. When implemented as part of a broader strategy for health care delivery system and payment reform, HIE capability also can enable the use of analytic tools needed for population health management, patient engagement in care, and continuous learning and improvement. The diverse experiences of seven communities that participated in the three-year federal Beacon Community Program offer practical insight into factors influencing the technical architecture of exchange infrastructure and its role in supporting improved care, reduced cost, and a healthier population. The case studies also document challenges faced by the communities, such as significant time and resources required to harmonize variations in the interpretation of data standards. Findings indicate that their progress developing community-based HIE strategies, while driven by local needs and objectives, is also influenced by broader legal, policy, and market conditions.

  8. Quantum Dot-Fullerene Based Molecular Beacon Nanosensors for Rapid, Highly Sensitive Nucleic Acid Detection.

    Liu, Ye; Kannegulla, Akash; Wu, Bo; Cheng, Li-Jing

    2018-05-15

    Spherical fullerene (C 60 ) can quench the fluorescence of a quantum dot (QD) through energy transfer and charge transfer processes, with the quenching efficiency regulated by the number of proximate C 60 on each QD. With the quenching property and its small size compared with other nanoparticle-based quenchers, it is advantageous to group a QD reporter and multiple C 60 -labeled oligonucleotide probes to construct a molecular beacon (MB) probe for sensitive, robust nucleic acid detection. We demonstrated a rapid, high-sensitivity DNA detection method using the nanosensors composed of QD-C 60 based MBs carried by magnetic nanoparticles (MNPs). The assay was accelerated by first dispersing the nanosensors in analytes for highly efficient DNA capture resulting from short-distance 3-dimensional diffusion of targets to the sensor surface and then concentrating the nanosensors to a substrate by magnetic force to amplify the fluorescence signal for target quantification. The enhanced mass transport enabled a rapid detection (< 10 min) with a small sample volume (1-10 µl). The high signal-to-noise ratio produced by the QD-C 60 pairs and magnetic concentration yielded a detection limit of 100 fM (~106 target DNA copies for a 10 µl analyte). The rapid, sensitive, label-free detection method will benefit the applications in point-of-care molecular diagnostic technologies.

  9. The keys to governance and stakeholder engagement: the southeast michigan beacon community case study.

    Des Jardins, Terrisca R

    2014-01-01

    Community-based health information exchanges (HIEs) and efforts to consolidate and house data are growing, given the advent of Accountable Care Organizations (ACOs) under the Affordable Care Act and other similar population health focused initiatives. The Southeast Michigan Beacon Community (SEMBC) can be looked to as one case study that offers lessons learned, insights on challenges faced and accompanying workarounds related to governance and stakeholder engagement. The SEMBC case study employs an established Data Warehouse Governance Framework to identify and explain the necessary governance and stakeholder engagement components, particularly as they relate to community-wide data sharing and data warehouses or repositories. Perhaps the biggest lesson learned through the SEMBC experience is that community-based work is hard. It requires a great deal of community leadership, collaboration and resources. SEMBC found that organizational structure and guiding principles needed to be continually revisited and nurtured in order to build the relationships and trust needed among stakeholder organizations. SEMBC also found that risks and risk mitigation tactics presented challenges and opportunities at the outset and through the duration of the three year pilot period. Other communities across the country embarking on similar efforts need to consider realistic expectations about community data sharing infrastructures and the accompanying and necessary governance and stakeholder engagement fundamentals.

  10. VLC-beacon detection with an under-sampled ambient light sensor

    Green, Jacob; Pérez-Olivas, Huetzin; Martínez-Díaz, Saúl; García-Márquez, Jorge; Domínguez-González, Carlos; Santiago-Montero, Raúl; Guan, Hongyu; Rozenblat, Marc; Topsu, Suat

    2017-08-01

    LEDs will replace in a near future the current worldwide lighting mainly due to their low production-cost and energy-saving assets. Visible light communications (VLC) will turn gradually the existing lighting network into a communication network. Nowadays VLC transceivers can be found in some commercial centres in Europe; some of them broadcast continuously an identification tag that contains its coordinate position. In such a case, the transceiver acts as a geolocation beacon. Nevertheless, mobile transceivers represent a challenge in the VLC communication chain, as smartphones have not integrated yet a VLC customized detection stage. In order to make current smartphones capable to detect VLC broadcasted signals, their Ambient Light Sensor (ALS) is adapted as a VLC detector. For this to be achieved, lighting transceivers need to adapt their modulation scheme. For instance, frequencies representing start bit, 1, and 0 logic values can be set to avoid flicker from illumination and to permit detecting the under-sampled signal. Decoding the signal requires a multiple steps real-time signal processing as shown here.

  11. Space Radar Image of Bahia

    1994-01-01

    This is a color composite image of southern Bahia, Brazil, centered at 15.22 degree south latitude and 39.07 degrees west longitude. The image was acquired by the Spaceborne Imaging Radar-C/X-band Synthetic Aperture Radar aboard the space shuttle Endeavour on its 38th orbit of Earth on October 2, 1994. The image covers an area centered over the Una Biological Reserve, one the largest protected areas in northeastern Brazil. The 7,000-hectare reserve is administered by the Brazilian Institute for the Environment and is part of the larger Atlantic coastal forest, a narrow band of rain forest extending along the eastern coast of Brazil. The Atlantic coastal forest of southern Bahia is one of the world's most threatened and diverse ecosystems. Due to widespread settlement, only 2 to 5 percent of the original forest cover remains. Yet the region still contains an astounding variety of plants and animals, including a large number of endemic species. More than half of the region's tree species and 80 percent of its animal species are indigenous and found nowhere else on Earth. The Una Reserve is also the only federally protected habitat for the golden-headed lion tamarin, the yellow-breasted capuchin monkey and many other endangered species. In the past few years, scientists from Brazilian and international conservation organizations have coordinated efforts to study the biological diversity of this region and to develop practical and economically viable options for preserving the remaining primary forests in southern Bahia. The shuttle imaging radar is used in this study to identify various land uses and vegetation types, including remaining patches of primary forest, cabruca forest (cacao planted in the understory of the native forest), secondary forest, pasture and coastal mangrove. Standard remote-sensing technology that relies on light reflected from the forest canopy cannot accurately distinguish between cabruca and undisturbed forest. Optical remote sensing is also

  12. Progress in coherent laser radar

    Vaughan, J. M.

    1986-01-01

    Considerable progress with coherent laser radar has been made over the last few years, most notably perhaps in the available range of high performance devices and components and the confidence with which systems may now be taken into the field for prolonged periods of operation. Some of this increasing maturity was evident at the 3rd Topical Meeting on Coherent Laser Radar: Technology and Applications. Topics included in discussions were: mesoscale wind fields, nocturnal valley drainage and clear air down bursts; airborne Doppler lidar studies and comparison of ground and airborne wind measurement; wind measurement over the sea for comparison with satellite borne microwave sensors; transport of wake vortices at airfield; coherent DIAL methods; a newly assembled Nd-YAG coherent lidar system; backscatter profiles in the atmosphere and wavelength dependence over the 9 to 11 micrometer region; beam propagation; rock and soil classification with an airborne 4-laser system; technology of a global wind profiling system; target calibration; ranging and imaging with coherent pulsed and CW system; signal fluctuations and speckle. Some of these activities are briefly reviewed.

  13. BALTRAD Advanced Weather Radar Networking

    Daniel Michelson

    2018-03-01

    Full Text Available BALTRAD software exchanges weather-radar data internationally, operationally, and in real-time, and it processes the data using a common toolbox of algorithms available to every node in the decentralized radar network. This approach enables each node to access and process its own and international data to meet its local needs. The software system is developed collaboratively by the BALTRAD partnership, mostly comprising the national Meteorological and Hydrological institutes in the European Union’s Baltic Sea Region. The most important sub-systems are for data exchange, data management, scheduling and event handling, and data processing. C, Java, and Python languages are used depending on the sub-system, and sub-systems communicate using well-defined interfaces. Software is available from a dedicated Git server. BALTRAD software has been deployed throughout Europe and more recently in Canada. Funding statement: From 2009–2014, the BALTRAD and BALTRAD+ projects were part-financed by the European Union (European Regional Development Fund and European Neighbourhood and Partnership Instrument, with project numbers #009 and #101, respectively.

  14. Space Radar Image of Chernobyl

    1994-01-01

    This is an image of the Chernobyl nuclear power plant and its surroundings, centered at 51.17 north latitude and 30.15 west longitude. The image was acquired by the Spaceborne Imaging Radar-C and X-band Synthetic Aperture Radar aboard the space shuttle Endeavour on its 16th orbit on October 1, 1994. The area is located on the northern border of the Ukraine Republic and was produced by using the L-band (horizontally transmitted and received) polarization. The differences in the intensity are due to differences in vegetation cover, with brighter areas being indicative of more vegetation. These data were acquired as part of a collaboration between NASA and the National Space Agency of Ukraine in Remote Sensing and Earth Sciences. NASA has included several sites provided by the Ukrainian space agency as targets of opportunity during the second flight of SIR-C/X-SAR. The Ukrainian space agency also plans to conduct airborne surveys of these sites during the mission. The Chernobyl nuclear power plant is located toward the top of the image near the Pripyat River. The 12-kilometer (7.44-mile)-long cooling pond is easily distinguishable as an elongated dark shape in the center near the top of the image. The reactor complex is visible as the bright area to the extreme left of the cooling pond and the city of Chernobyl is the bright area just below the cooling pond next to the Pripyat River. The large dark area in the bottom right of the image is the Kiev Reservoir just north of Kiev. Also visible is the Dnieper River, which feeds into the Kiev Reservoir from the top of the image. The Soviet government evacuated 116,000 people within 30 kilometers (18.6 miles) of the Chernobyl reactor after the explosion and fire on April 26, 1986. Spaceborne Imaging Radar-C and X-band Synthetic Aperture Radar (SIR-C/X-SAR) is part of NASA's Mission to Planet Earth. The radars illuminate Earth with microwaves, allowing detailed observations at any time, regardless of weather or sunlight

  15. Gold nanoparticle-based beacon to detect STAT5b mRNA expression in living cells: a case optimized by bioinformatics screen.

    Deng, Dawei; Li, Yang; Xue, Jianpeng; Wang, Jie; Ai, Guanhua; Li, Xin; Gu, Yueqing

    2015-01-01

    Messenger RNA (mRNA), a single-strand ribonucleic acid with functional gene information is usually abnormally expressed in cancer cells and has become a promising biomarker for the study of tumor progress. Hairpin DNA-coated gold nanoparticle (hDAuNP) beacon containing a bare gold nanoparticle (AuNP) as fluorescence quencher and thiol-terminated fluorescently labeled stem-loop-stem oligonucleotide sequences attached by Au-S bond is currently a new nanoscale biodiagnostic platform capable of mRNA detection, in which the design of the loop region sequence is crucial for hybridizing with the target mRNA. Hence, in this study, to improve the sensitivity and selectivity of hDAuNP beacon simultaneously, the loop region of hairpin DNA was screened by bioinformatics strategy. Here, signal transducer and activator of transcription 5b (STAT5b) mRNA was selected and used as a practical example. The results from the combined characterizations using optical techniques, flow cytometry assay, and cell microscopic imaging showed that after optimization, the as-prepared hDAuNP beacon had higher selectivity and sensitivity for the detection of STAT5b mRNA in living cells, as compared with our previous beacon. Thus, the bioinformatics method may be a promising new strategy for assisting in the designing of the hDAuNP beacon, extending its application in the detection of mRNA expression and the resultant mRNA-based biological processes and disease pathogenesis.

  16. Radar

    Nielsen, Tom

    2009-01-01

    Bidrag til arkitektens opgørelse (baseret på en række forskellige indlæg) over hvor dansk arkitektur står, med korte bud på spørgsmålene: Kan man ud over stedsanknytningen tale om en særlig dansk arkitektur?, Hvad er dansk arkitekturs største kvalitet, vores vigtigste force? og Hvad er dansk arki...

  17. Cloning of regions required for contact hemolysis and entry into LLC-MK2 cells from Shigella sonnei form I plasmid: virF is a positive regulator gene for these phenotypes.

    Kato, J; Ito, K; Nakamura, A; Watanabe, H

    1989-01-01

    Two distinct regions required for both contact hemolysis and entry into LLC-MK2 cells were cloned into Escherichia coli from the Shigella sonnei form I plasmid, pSS120. The first region was cloned into an E. coli HB101 strain containing noninvasive Tn1 insertion mutants of the form I plasmid, and expression of ipa (invasion plasmid antigen) gene products was restored. The plasmid carrying the first region was then transformed into E. coli lacking the form I plasmid, and additional DNA fragmen...

  18. Survey of Ultra-wideband Radar

    Mokole, Eric L.; Hansen, Pete

    The development of UWB radar over the last four decades is very briefly summarized. A discussion of the meaning of UWB is followed by a short history of UWB radar developments and discussions of key supporting technologies and current UWB radars. Selected UWB radars and the associated applications are highlighted. Applications include detecting and imaging buried mines, detecting and mapping underground utilities, detecting and imaging objects obscured by foliage, through-wall detection in urban areas, short-range detection of suicide bombs, and the characterization of the impulse responses of various artificial and naturally occurring scattering objects. In particular, the Naval Research Laboratory's experimental, low-power, dual-polarized, short-pulse, ultra-high resolution radar is used to discuss applications and issues of UWB radar. Some crucial issues that are problematic to UWB radar are spectral availability, electromagnetic interference and compatibility, difficulties with waveform control/shaping, hardware limitations in the transmission chain, and the unreliability of high-power sources for sustained use above 2 GHz.

  19. New look at radar auroral motions

    Greenwald, R.A.; Ecklund, W.L.

    1975-01-01

    During October 1974, three modifications were temporarily added to the NOAA radar auroral backscatter facility located at Anchorage, Alaska. These modifications included (1) a multiple azimuth antenna system. (2) an on-line computer for processing amplitude and mean Doppler profiles of the radar backscatter, and (3) a 13-baud Barker coder. In combination with the radar these modifications provided data relevant to understanding both the microscopic and the macroscopic nature of the radar aurora. Appreciable structure was often found in the Doppler velocity profiles of radar auroral irregularities. Doppler velocities of nearly 2000 m/s were observed. By combining scatter amplitude profiles and mean Doppler profiles from the five azimuths we have produced contour maps of the scatter intensity and the Doppler velocity. The scatter intensity maps often indicate appreciable temporal and spatial structure in the radar auroral irregularities, corroborating the results of Tsunoda et al. (1974). The mean Doppler contour maps indicate that there is also appreciable temporal and spatial structure in the flow velocities of radar auroral irregularities. At those times when there appears to be large-scale uniformity in the irregularity flow, the Doppler velocity varies with azimuth in a manner that is consistent with a cosine-dependent azimuthal variation

  20. Condor equatorial electrojet campaign: Radar results

    Kudeki, E.; Fejer, B.G.; Farley, D.T.; Hanuise, C.

    1987-01-01

    A review of the experimental and theoretical background to the Condor equatorial electrojet compaign is followed by the presentation and discussion of VHF radar interferometer and HF radar backscatter data taken concurrently with two rocket in situ experiments reported in companion papers (Pfaff et al., this issue (a, b). Both experiments were conducted in strongly driven periods with the on-line radar interferometer displaying signatures of what has been interpreted in earlier radar work (Kudeki et al., 1982) as kilometer scale gradient drift waves. Low-frequency density fluctuations detected by in situ rocket sensors confirm the earlier interpretation. VHF radar/rocket data comparisons also indicate the existence of a turbulent layer in the upper portion of the daytime electrojet at about 108 km altitude driven purely by the two-stream instability. Nonlinear mode coupling of linearly growing two-stream waves to linearly damped 3-m vertical modes could account for the radar echoes scattered from this layer, which showed no indication of large-scale gradient drift waves. Nonlinear mode coupling may therefore compete with the wave-induced anomalous diffusion mechanism proposed recently by Sudan (1983) for the saturation of directly excited two-stream waves. Nighttime radar data show a bifurcated layer with the two parts having comparable echo strength but oppositely directed zonal drift velocities. The lower layer shows narrow backscatter spectra; the upper layer is characterized by kilometer scale waves and vertically propagating type 1 waves

  1. Using phase for radar scatterer classification

    Moore, Linda J.; Rigling, Brian D.; Penno, Robert P.; Zelnio, Edmund G.

    2017-04-01

    Traditional synthetic aperture radar (SAR) systems tend to discard phase information of formed complex radar imagery prior to automatic target recognition (ATR). This practice has historically been driven by available hardware storage, processing capabilities, and data link capacity. Recent advances in high performance computing (HPC) have enabled extremely dense storage and processing solutions. Therefore, previous motives for discarding radar phase information in ATR applications have been mitigated. First, we characterize the value of phase in one-dimensional (1-D) radar range profiles with respect to the ability to correctly estimate target features, which are currently employed in ATR algorithms for target discrimination. These features correspond to physical characteristics of targets through radio frequency (RF) scattering phenomenology. Physics-based electromagnetic scattering models developed from the geometrical theory of diffraction are utilized for the information analysis presented here. Information is quantified by the error of target parameter estimates from noisy radar signals when phase is either retained or discarded. Operating conditions (OCs) of signal-tonoise ratio (SNR) and bandwidth are considered. Second, we investigate the value of phase in 1-D radar returns with respect to the ability to correctly classify canonical targets. Classification performance is evaluated via logistic regression for three targets (sphere, plate, tophat). Phase information is demonstrated to improve radar target classification rates, particularly at low SNRs and low bandwidths.

  2. Pedestrian recognition using automotive radar sensors

    Bartsch, A.; Fitzek, F.; Rasshofer, R. H.

    2012-09-01

    The application of modern series production automotive radar sensors to pedestrian recognition is an important topic in research on future driver assistance systems. The aim of this paper is to understand the potential and limits of such sensors in pedestrian recognition. This knowledge could be used to develop next generation radar sensors with improved pedestrian recognition capabilities. A new raw radar data signal processing algorithm is proposed that allows deep insights into the object classification process. The impact of raw radar data properties can be directly observed in every layer of the classification system by avoiding machine learning and tracking. This gives information on the limiting factors of raw radar data in terms of classification decision making. To accomplish the very challenging distinction between pedestrians and static objects, five significant and stable object features from the spatial distribution and Doppler information are found. Experimental results with data from a 77 GHz automotive radar sensor show that over 95% of pedestrians can be classified correctly under optimal conditions, which is compareable to modern machine learning systems. The impact of the pedestrian's direction of movement, occlusion, antenna beam elevation angle, linear vehicle movement, and other factors are investigated and discussed. The results show that under real life conditions, radar only based pedestrian recognition is limited due to insufficient Doppler frequency and spatial resolution as well as antenna side lobe effects.

  3. Foliage penetration radar detection and characterization of objects under trees

    Davis, Mark

    2011-01-01

    This book covers all aspects of foliage penetration (FOPEN) radar, concentrating on both airborne military radar systems as well as earth resource mapping radars. It is the first concise and thorough treatment of FOPEN, covering the results of a decade-long investment by DARPA in characterizing foliage and earth surface with ultrawideband UHF and VHF synthetic aperture radar (SAR).

  4. The use of radar for bathymetry in shallow seas

    Greidanus, H.

    1997-01-01

    The bottom topography in shallow seas can be observed by air- and space borne radar. The paper reviews the radar imaging mechanism, and discusses the possibilities and limitations for practical use of radar in bathymetric applications, including the types of radar instruments available for this

  5. Radar ornithology and the conservation of migratory birds

    Sidney A. Gauthreaux; Carroll G. Belser

    2005-01-01

    It is possible to study with surveillance radar the movements of migrating birds in the atmosphere at different spatial scales. At a spatial scale within a range of 6 kilometers, high-resolution, 3-centimeter wavelength surveillance radar (e.g. BIRDRAD) can detect the departure of migrants from different types of habitat within a few kilometers of the radar. The radar...

  6. Application of a molecular beacon based real-time isothermal amplification (MBRTIA) technology for simultaneous detection of Bacillus cereus and Staphylococcus aureus.

    Mandappa, I M; Joglekar, Prasanna; Manonmani, H K

    2015-07-01

    A multiplex real-time isothermal amplification assay was developed using molecular beacons for the detection of Bacillus cereus and Staphylococcus aureus by targeting four important virulence genes. A correlation between targeting highly accessible DNA sequences and isothermal amplification based molecular beacon efficiency and sensitivity was demonstrated using phi(Φ)29 DNA polymerase at a constant isothermal temperature of 30 °C. It was very selective and consistently detected down to 10(1) copies of DNA. The specificity and sensitivity of this assay, when tested with pure culture were high, surpassing those of currently used PCR assays for the detection of these organisms. The molecular beacon based real-time isothermal amplification (MBRTIA) assay could be carried out entirely in 96 well plates or well strips, enabling a rapid and high-throughput detection of food borne pathogens.

  7. Radar Exploration of Cometary Nuclei

    Gim, Yonggyu; Heggy, E.; Belton, M.; Weissman, P.; Asphaug, E.

    2012-10-01

    We have developed a mission formulation, based on the use of previously flown planetary radar sounding techniques, to image the 3D internal structure of the nucleus of a Jupiter-family comet (JFC). Believed to originate in the outer solar system and to be delivered recently to the inner solar system from the Kuiper Belt, JFCs are among the most primitive bodies accessible by spacecraft, and are indicated in the 2010 Decadal Survey as primary targets for primitive bodies sample return. We consider a sounder design operating at dual frequencies, 5 and 15 MHz center frequencies with 1 and 10 MHz bandwidths, respectively. Operating from close orbit about the nucleus of a spinning comet nucleus, CORE obtains a dense network of echoes that are used to image its interior structure to 10 m and to map the dielectric properties inside the nucleus to better than 200 m throughout. Clear images of internal structure and dielectric composition will reveal how the nucleus was formed and how it has evolved. Radiometric tracking of the spacecraft orbit will provide an interior mass distribution that constrains the radar-based models of interior composition. High-resolution visible and infrared color images provide surface and exterior boundary conditions for interior models and hypotheses. They present the geology and morphology of the nucleus surface at meter-scales, and the time-evolving activity, structure, and composition of the inner coma. By making global yet detailed connections from interior to exterior, the data from CORE will provide answers to fundamental questions about the earliest stages of planetesimal evolution and planet formation, will be an important complement to the Rosetta mission science, and will lay the foundation for comet nucleus sample return.

  8. Radar, sonar, and holography an introduction

    Kock, Winston E

    1974-01-01

    Radar, Sonar, and Holography: An Introduction provides an introduction to the technology of radar and sonar. Because the new science of holography is affecting both these fields quite strongly, the book includes an explanation of the fundamental principles underlying this new art (including the subjects of wave coherence, interference, and diffraction) and of the hologram process itself. Finally, numerous examples are discussed which show how holography is providing new horizons to radar and sonar systems. The book thus also provides a simple approach to the new technology of holography. The

  9. New Vacuum Electronic Devices for Radar

    Hu Yinfu

    2016-08-01

    Full Text Available Vacuum Electronic Devices (VEDs which are considered as the heart of a radar system, play an important role in their development. VEDs and radar systems supplement and promote each other. Some new trends in VEDs have been observed with advancements in the simulation tools for designing VEDs, new materials, new fabrication techniques. Recently, the performance of VEDs has greatly improved. In addition, new devices have been invented, which have laid the foundation for the developments of radar detection technology. This study introduces the recent development trends and research results of VEDs from microwave and millimeter wave devices and power modules, integrated VEDs, terahertz VEDs, and high power VEDs.

  10. Image Registration Methode in Radar Interferometry

    S. Chelbi

    2015-08-01

    Full Text Available This article presents a methodology for the determination of the registration of an Interferometric Synthetic radar (InSAR pair images with half pixel precision. Using the two superposed radar images Single Look complexes (SLC [1-4], we developed an iterative process to superpose these two images according to their correlation coefficient with a high coherence area. This work concerns the exploitation of ERS Tandem pair of radar images SLC of the Algiers area acquired on 03 January and 04 January 1994. The former is taken as a master image and the latter as a slave image.

  11. Radar signal processing and its applications

    Hummel, Robert; Stoica, Petre; Zelnio, Edmund

    2003-01-01

    Radar Signal Processing and Its Applications brings together in one place important contributions and up-to-date research results in this fast-moving area. In twelve selected chapters, it describes the latest advances in architectures, design methods, and applications of radar signal processing. The contributors to this work were selected from the leading researchers and practitioners in the field. This work, originally published as Volume 14, Numbers 1-3 of the journal, Multidimensional Systems and Signal Processing, will be valuable to anyone working or researching in the field of radar signal processing. It serves as an excellent reference, providing insight into some of the most challenging issues being examined today.

  12. Signal compression in radar using FPGA

    Enrique Escamilla Hemández; Víctor Kravchenko; Volodymyr Ponomaryov; Gonzalo Duchen Sánchez; David Hernández Sánchez

    2010-01-01

    El presente artículo muestra la puesta en práctica de hardware para realizar el procesamiento en tiempo real de la señal de radar usando una técnica simple, rápida basada en arquitectura de FPGA (Field Programmable Gate Array). El proceso incluye diversos procedimientos de enventanado durante la compresión del pulso del radar de apertura sintética (SAR). El proceso de compresión de la señal de radar se hace con un filtro acoplado. que aplica funciones clásicas y nuevas de enventanado, donde n...

  13. Radar orthogonality and radar length in Finsler and metric spacetime geometry

    Pfeifer, Christian

    2014-09-01

    The radar experiment connects the geometry of spacetime with an observers measurement of spatial length. We investigate the radar experiment on Finsler spacetimes which leads to a general definition of radar orthogonality and radar length. The directions radar orthogonal to an observer form the spatial equal time surface an observer experiences and the radar length is the physical length the observer associates to spatial objects. We demonstrate these concepts on a forth order polynomial Finsler spacetime geometry which may emerge from area metric or premetric linear electrodynamics or in quantum gravity phenomenology. In an explicit generalization of Minkowski spacetime geometry we derive the deviation from the Euclidean spatial length measure in an observers rest frame explicitly.

  14. Gold nanoparticle-based beacon to detect STAT5b mRNA expression in living cells: a case optimized by bioinformatics screen

    Deng D

    2015-04-01

    Full Text Available Dawei Deng,* Yang Li,* Jianpeng Xue, Jie Wang, Guanhua Ai, Xin Li, Yueqing GuDepartment of Biomedical Engineering, China Pharmaceutical University, Nanjing, People’s Republic of China*These authors contributed equally to this workAbstract: Messenger RNA (mRNA, a single-strand ribonucleic acid with functional gene information is usually abnormally expressed in cancer cells and has become a promising biomarker for the study of tumor progress. Hairpin DNA-coated gold nanoparticle (hDAuNP beacon containing a bare gold nanoparticle (AuNP as fluorescence quencher and thiol-terminated fluorescently labeled stem–loop–stem oligonucleotide sequences attached by Au–S bond is currently a new nanoscale biodiagnostic platform capable of mRNA detection, in which the design of the loop region sequence is crucial for hybridizing with the target mRNA. Hence, in this study, to improve the sensitivity and selectivity of hDAuNP beacon simultaneously, the loop region of hairpin DNA was screened by bioinformatics strategy. Here, signal transducer and activator of transcription 5b (STAT5b mRNA was selected and used as a practical example. The results from the combined characterizations using optical techniques, flow cytometry assay, and cell microscopic imaging showed that after optimization, the as-prepared hDAuNP beacon had higher selectivity and sensitivity for the detection of STAT5b mRNA in living cells, as compared with our previous beacon. Thus, the bioinformatics method may be a promising new strategy for assisting in the designing of the hDAuNP beacon, extending its application in the detection of mRNA expression and the resultant mRNA-based biological processes and disease pathogenesis.Keywords: molecular beacon, bioinformatics, gold nanoparticle, STAT5b mRNA, visual detection

  15. Theragnosis-based combined cancer therapy using doxorubicin-conjugated microRNA-221 molecular beacon.

    Lee, Jonghwan; Choi, Kyung-Ju; Moon, Sung Ung; Kim, Soonhag

    2016-01-01

    Recently, microRNA (miRNA or miR) has emerged as a new cancer biomarker because of its high expression level in various cancer types and its role in the control of tumor suppressor genes. In cancer studies, molecular imaging and treatment based on target cancer markers have been combined to facilitate simultaneous cancer diagnosis and therapy. In this study, for combined therapy with diagnosis of cancer, we developed a doxorubicin-conjugated miR-221 molecular beacon (miR-221 DOXO MB) in a single platform composed of three different nucleotides: miR-221 binding sequence, black hole quencher 1 (BHQ1), and doxorubicin binding site. Imaging of endogenous miR-221 was achieved by specific hybridization between miR-221 and the miR-221 binding site in miR-221 DOXO MB. The presence of miR-221 triggered detachment of the quencher oligo and subsequent activation of a fluorescent signal of miR-221 DOXO MB. Simultaneous cancer therapy in C6 astrocytoma cells and nude mice was achieved by inhibition of miRNA-221 function that downregulates tumor suppressor genes. The detection of miR-221 expression and inhibition of miR-221 function by miR-221 DOXO MB provide the feasibility as a cancer theragnostic probe. Furthermore, a cytotoxic effect was induced by unloading of doxorubicin intercalated into miR-221 DOXO MB inside cells. Loss of miR-221 function and cytotoxicity induced by the miR-221 DOXO MB provides combined therapeutic efficacy against cancers. This method could be used as a new theragnostic probe with enhanced therapy to detect and inhibit many cancer-related miRNAs. Copyright © 2015 Elsevier Ltd. All rights reserved.

  16. Detection of Naja atra Cardiotoxin Using Adenosine-Based Molecular Beacon.

    Shi, Yi-Jun; Chen, Ying-Jung; Hu, Wan-Ping; Chang, Long-Sen

    2017-01-07

    This study presents an adenosine (A)-based molecular beacon (MB) for selective detection of Naja atra cardiotoxin (CTX) that functions by utilizing the competitive binding between CTX and the poly(A) stem of MB to coralyne. The 5'- and 3'-end of MB were labeled with a reporter fluorophore and a non-fluorescent quencher, respectively. Coralyne induced formation of the stem-loop MB structure through A₂-coralyne-A₂ coordination, causing fluorescence signal turn-off due to fluorescence resonance energy transfer between the fluorophore and quencher. CTX3 could bind to coralyne. Moreover, CTX3 alone induced the folding of MB structure and quenching of MB fluorescence. Unlike that of snake venom α-neurotoxins, the fluorescence signal of coralyne-MB complexes produced a bell-shaped concentration-dependent curve in the presence of CTX3 and CTX isotoxins; a turn-on fluorescence signal was noted when CTX concentration was ≤80 nM, while a turn-off fluorescence signal was noted with a further increase in toxin concentrations. The fluorescence signal of coralyne-MB complexes yielded a bell-shaped curve in response to varying concentrations of N. atra crude venom but not those of Bungarus multicinctus and Protobothrops mucrosquamatus venoms. Moreover, N. nigricollis venom also functioned as N. atra venom to yield a bell-shaped concentration-dependent curve of MB fluorescence signal, again supporting that the hairpin-shaped MB could detect crude venoms containing CTXs. Taken together, our data validate that a platform composed of coralyne-induced stem-loop MB structure selectively detects CTXs.

  17. G-Quadruplex DNAzyme Molecular Beacon for Amplified Colorimetric Biosensing of Pseudostellaria heterophylla

    Juan Hu

    2013-01-01

    Full Text Available With an internal transcribed spacer of 18 S, 5.8 S and 26 S nuclear ribosomal DNA (nrDNA ITS as DNA marker, we report a colorimetric approach for authentication of Pseudostellaria heterophylla (PH and its counterfeit species based on the differentiation of the nrDNA ITS sequence. The assay possesses an unlabelled G-quadruplex DNAzyme molecular beacon (MB probe, employing complementary sequence as biorecognition element and 1:1:1:1 split G-quadruplex halves as reporter. In the absence of target DNA (T-DNA, the probe can shape intermolecular G-quadruplex structures capable of binding hemin to form G-quadruplex-hemin DNAzyme and catalyze the oxidation of ABTS2− to blue-green ABTS•− by H2O2. In the presence of T-DNA, T-DNA can hybridize with the complementary sequence to form a duplex structure, hindering the formation of the G-quadruplex structure and resulting in the loss of the catalytic activity. Consequently, a UV-Vis absorption signal decrease is observed in the ABTS2−-H2O2 system. The “turn-off” assay allows the detection of T-DNA from 1.0 × 10−9 to 3.0 × 10−7 mol·L−1 (R2 = 0.9906, with a low detection limit of 3.1 × 10−10 mol·L−1. The present study provides a sensitive and selective method and may serve as a foundation of utilizing the DNAzyme MB sensor for identifying traditional Chinese medicines.

  18. The journey of primary care practices to meaningful use: a Colorado Beacon Consortium study.

    Fernald, Douglas H; Wearner, Robyn; Dickinson, W Perry

    2013-01-01

    The Health Information Technology for Economic and Clinical Health Act of 2009 provides for incentive payments through Medicare and Medicaid for clinicians who implement electronic health records (EHRs) and use this technology meaningfully to improve patient care. There are few comprehensive descriptions of how primary care practices achieve the meaningful use of clinical data, including the formal stage 1 meaningful use requirements. Evaluation of the Colorado Beacon Consortium project included iterative qualitative analysis of practice narratives, provider and staff interviews, and separate focus groups with quality improvement (QI) advisors and staff from the regional health information exchange (HIE). Most practices described significant realignment of practice priorities and aims, which often required substantial education and training of physicians and staff. Re-engineering office processes, data collection protocols, EHRs, staff roles, and practice culture comprised the primary effort and commitment to attest to stage 1 meaningful use and subsequent meaningful use of clinical data. While realizing important benefits, practices bore a significant burden in learning the true capabilities of their EHRs with little effective support from vendors. Attestation was an important initial milestone in the process, but practices faced substantial ongoing work to use their data meaningfully for patient care and QI. Key resources were instrumental to these practices: local technical EHR expertise; collaborative learning mechanisms; and regular contact and support from QI advisors. Meeting the stage 1 requirements for incentives under Medicare and Medicaid meaningful use criteria is the first waypoint in a longer journey by primary care practices to the meaningful use of electronic data to continuously improve the care and health of their patients. The intensive re-engineering effort for stage 1 yielded practice changes consistent with larger practice aims and goals

  19. A Biofunctional Molecular Beacon for Detecting Single Base Mutations in Cancer Cells

    Haiyan Dong

    2016-01-01

    Full Text Available The development of a convenient and sensitive biosensing system to detect specific DNA sequences is an important issue in the field of genetic disease therapy. As a classic DNA detection technique, molecular beacon (MB is often used in the biosensing system. However, it has intrinsic drawbacks, including high assay cost, complicated chemical modification, and operational complexity. In this study, we developed a simple and cost-effective label-free multifunctional MB (LMMB by integrating elements of polymerization primer, template, target recognition, and G-quadruplex into one entity to detect target DNA. The core technique was accomplished by introducing a G-hairpin that features fragments of both G-quadruplex and target DNA recognition in the G-hairpin stem. Hybridization between LMMB and target DNA triggered conformational change between the G-hairpin and the common C-hairpin, resulting in significant SYBR-green signal amplification. The hybridization continues to the isothermal circular strand-displacement polymerization and accumulation of the double-stranded fragments, causing the uninterrupted extension of the LMMB without a need of chemical modification and other assistant DNA sequences. The novel and programmable LMMB could detect target DNA with sensitivity at 250 pmol/l with a linear range from 2 to 100 nmol/l and the relative standard deviation of 7.98%. The LMMB could sense a single base mutation from the normal DNA, and polymerase chain reaction (PCR amplicons of the mutant-type cell line from the wild-type one. The total time required for preparation and assaying was only 25 minutes. Apparently, the LMMB shows great potential for detecting DNA and its mutations in biosamples, and therefore it opens up a new prospect for genetic disease therapy.

  20. Experimental Analysis of Sublimation Dynamics for Buried Glacier Ice in Beacon Valley, Antarctica

    Ehrenfeucht, S.; Dennis, D. P.; Marchant, D. R.

    2017-12-01

    The age of the oldest known buried ice in Beacon Valley, McMurdo Dry Valleys (MDV) Antarctica is a topic of active debate due to its implications for the stability of the East Antarctic Ice Sheet. Published age estimates range from as young as 300 ka to as old as 8.1 Ma. In the upland MDV, ablation occurs predominantly via sublimation. The relict ice in question (ancient ice from Taylor Glacier) lies buried beneath a thin ( 30-70 cm) layer of sublimation till, which forms as a lag deposit as underlying debris-rich ice sublimes. As the ice sublimates, the debris held within the ice accumulates slowly on the surface, creating a porous boundary between the buried-ice surface and the atmosphere, which in turn influences gas exchange between the ice and the atmosphere. Additionally, englacial debris adds several salt species that are ultimately concentrated on the ice surface. It is well documented the rate of ice sublimation varies as a function of overlying till thickness. However, the rate-limiting dynamics under varying environmental conditions, including the threshold thicknesses at which sublimation is strongly retarded, are not yet defined. To better understand the relationships between sublimation rate, till thickness, and long-term surface evolution, we build on previous studies by Lamp and Marchant (2017) and evaluate the role of till thickness as a control on ice loss in an environmental chamber capable of replicating the extreme cold desert conditions observed in the MDV. Previous work has shown that this relationship exhibits exponential decay behavior, with sublimation rate significantly dampened under less than 10 cm of till. In our experiments we pay particular attention to the effect of the first several cm of till in order to quantify the dynamics that govern the transition from bare ice to debris-covered ice. We also examine this transition for various forms of glacier ice, including ice with various salt species.

  1. Potential effects of the introduction of the discrete address beacon system data link on air/ground information transfer problems

    Grayson, R. L.

    1981-01-01

    This study of Aviation Safety Reporting System reports suggests that benefits should accure from implementation of discrete address beacon system data link. The phase enhanced terminal information system service is expected to provide better terminal information than present systems by improving currency and accuracy. In the exchange of air traffic control messages, discrete address insures that only the intended recipient receives and acts on a specific message. Visual displays and printer copy of messages should mitigate many of the reported problems associated with voice communications. The problems that remain unaffected include error in addressing the intended recipient and messages whose content is wrong but are otherwise correct as to format and reasonableness.

  2. Development Of Signal Detection For Radar Navigation System

    Theingi Win Hlaing; Hla Myo Tun; Zaw Min Naing; Win Khaing Moe

    2017-01-01

    This paper aims to evaluate the performance of target detection in the presence of sea clutter. Radar detection of a background of unwanted clutter due to echoes from sea clutter or land is a problem of interest in the radar field. Radar detector has been developed by assuming the radar clutter is Gaussian distributed. However as technology emerges the radar distribution is seen to deviates from the Gaussian assumption. Thus detectors designs based on Gaussian assumption are no longer optimum...

  3. Radar Polarimetry and Interferometry (La polarimetrie et l'interferometrie radar) (CD-ROM)

    Keydel, W; Boerner, W. M; Pottier, E; Lee, J. S; Ferro-Famil, L; Hellmann, M; Cloude, S. R

    2005-01-01

    ...: Scientists and engineers already engaged in the fields of radar surveillance, reconnaissance and scattering measurements, for instance, generally gain their specialist knowledge in both polarimetry...

  4. Synthetic impulse and aperture radar (SIAR) a novel multi-frequency MIMO radar

    Chen, Baixiao

    2014-01-01

    Analyzes and discusses the operating principle, signal processing method, and experimental results of this advanced radar technology This book systematically discusses the operating principle, signal processing method, target measurement technology, and experimental results of a new kind of radar called synthetic impulse and aperture radar (SIAR). The purpose is to help readers acquire an insight into the concept and principle of the SIAR, to know its operation mode, signal processing method, the difference between the traditional radar and itself, the designing ideals, and the developing me

  5. Greenland Radar Ice Sheet Thickness Measurements

    National Aeronautics and Space Administration — Two 150-MHz coherent radar depth sounders were developed and flown over the Greenland ice sheet to obtain ice thickness measurements in support of PARCA...

  6. Identifying structural damage with ground penetrating radar

    Van Schoor, Abraham M

    2008-07-01

    Full Text Available Ground penetrating radar (GPR) and electrical resistance tomography (ERT) surveys were conducted in an urban environment in an attempt to identify the cause of severe structural damage to a historically significant residential property...

  7. Simulating lightning tests to radar system

    Blaj, M.A.; Buesink, Frederik Johannes Karel; Leferink, Frank Bernardus Johannes

    2010-01-01

    The risk of destruction due to lightning makes simulating the effects of lightning strikes a necessity. We modeled a radar enclosure and simulated the effect of a lightning strike. The results have been validated using full threat lightning current tests.

  8. Airborne Radar Search for Diesel Submarines (ARSDS)

    Pilnick, Steven E; Landa, Jose

    2005-01-01

    .... In this research, a detection rate model is developed to analyze the effectiveness of an airborne radar search for a diesel submarine assumed to be intermittently operating with periscopes or masts...

  9. Airborne Radar Search for Diesel Submarines

    Pilnick, Steven E; Landa, Jose

    2005-01-01

    .... In this research, a detection rate model is developed to analyze the effectiveness of airborne radar search for a diesel submarine assumed to be intermittently operating with periscopes or masts...

  10. A radar-echo model for Mars

    Thompson, T.W.; Moore, H.J.

    1990-01-01

    Researchers developed a radar-echo model for Mars based on 12.6 cm continuous wave radio transmissions backscattered from the planet. The model broadly matches the variations in depolarized and polarized total radar cross sections with longitude observed by Goldstone in 1986 along 7 degrees S. and yields echo spectra that are generally similiar to the observed spectra. Radar map units in the model include an extensive cratered uplands unit with weak depolarized echo cross sections, average thermal inertias, moderate normal refelectivities, and moderate rms slopes; the volcanic units of Tharsis, Elysium, and Amazonis regions with strong depolarized echo cross sections, low thermal inertia, low normal reflectivities, and large rms slopes; and the northern planes units with moderate to strong depolarized echo cross sections, moderate to very high thermal inertias, moderate to large normal reflectivities, and moderate rms slopes. The relevance of the model to the interpretation of radar echoes from Mars is discussed

  11. UWB Sampler for Wireless Communications and Radar

    Han, Jeongwoo; Nguyen, Cam

    2005-01-01

    An ultra wideband (UWB) sampler, realized using step recovery and Schottky diodes on coplanar waveguide, coplanar strips and slotlines, has been developed for UWB wireless communications and radar systems...

  12. VERTICAL ACTIVITY ESTIMATION USING 2D RADAR

    hennie

    estimates on aircraft vertical behaviour from a single 2D radar track. ... Fortunately, the problem of detecting relative vertical motion using a single 2D ..... awareness tools in scenarios where aerial activity sensing is typically limited to 2D.

  13. Physical working principles of medical radar.

    Aardal, Øyvind; Paichard, Yoann; Brovoll, Sverre; Berger, Tor; Lande, Tor Sverre; Hamran, Svein-Erik

    2013-04-01

    There has been research interest in using radar for contactless measurements of the human heartbeat for several years. While many systems have been demonstrated, not much attention have been given to the actual physical causes of why this work. The consensus seems to be that the radar senses small body movements correlated with heartbeats, but whether only the movements of the body surface or reflections from internal organs are also monitored have not been answered definitely. There has recently been proposed another theory that blood perfusion in the skin could be the main reason radars are able to detect heartbeats. In this paper, an experimental approach is given to determine the physical causes. The measurement results show that it is the body surface reflections that dominate radar measurements of human heartbeats.

  14. Radar Training Facility Local Area Network -

    Department of Transportation — The RTF LAN system provides a progressive training environment for initial and refresher radar training qualification for new and re-hired FAA employees. Its purpose...

  15. Investigating nearby exoplanets via interstellar radar

    Scheffer, Louis K.

    2014-01-01

    Interstellar radar is a potential intermediate step between passive observation of exoplanets and interstellar exploratory missions. Compared with passive observation, it has the traditional advantages of radar astronomy. It can measure surface characteristics, determine spin rates and axes, provide extremely accurate ranges, construct maps of planets, distinguish liquid from solid surfaces, find rings and moons, and penetrate clouds. It can do this even for planets close to the parent star. Compared with interstellar travel or probes, it also offers significant advantages. The technology required to build such a radar already exists, radar can return results within a human lifetime, and a single facility can investigate thousands of planetary systems. The cost, although too high for current implementation, is within the reach of Earth's economy.

  16. Snowballing and flying under the radar

    Pötz, Katharina Anna; Hjortsø, Carsten Nico Portefée

    2013-01-01

    management and venture development paths. More specifically, flying under radar in terms of operating under lower institutional requirements, and slowly accumulating resources (snowballing) are major leveraging strategies. We integrate our results into a hypothesized framework for resource management in East...

  17. Architecture for a 1-GHz Digital RADAR

    Mallik, Udayan

    2011-01-01

    An architecture for a Direct RF-digitization Type Digital Mode RADAR was developed at GSFC in 2008. Two variations of a basic architecture were developed for use on RADAR imaging missions using aircraft and spacecraft. Both systems can operate with a pulse repetition rate up to 10 MHz with 8 received RF samples per pulse repetition interval, or at up to 19 kHz with 4K received RF samples per pulse repetition interval. The first design describes a computer architecture for a Continuous Mode RADAR transceiver with a real-time signal processing and display architecture. The architecture can operate at a high pulse repetition rate without interruption for an infinite amount of time. The second design describes a smaller and less costly burst mode RADAR that can transceive high pulse repetition rate RF signals without interruption for up to 37 seconds. The burst-mode RADAR was designed to operate on an off-line signal processing paradigm. The temporal distribution of RF samples acquired and reported to the RADAR processor remains uniform and free of distortion in both proposed architectures. The majority of the RADAR's electronics is implemented in digital CMOS (complementary metal oxide semiconductor), and analog circuits are restricted to signal amplification operations and analog to digital conversion. An implementation of the proposed systems will create a 1-GHz, Direct RF-digitization Type, L-Band Digital RADAR--the highest band achievable for Nyquist Rate, Direct RF-digitization Systems that do not implement an electronic IF downsample stage (after the receiver signal amplification stage), using commercially available off-the-shelf integrated circuits.

  18. Radar Location Equipment Development Program: Phase I

    Sandness, G.A.; Davis, K.C.

    1985-06-01

    The work described in this report represents the first phase of a planned three-phase project designed to develop a radar system for monitoring waste canisters stored in a thick layer of bedded salt at the Waste Isolation Pilot Plant near Carlsbad, New Mexico. The canisters will be contained in holes drilled into the floor of the underground waste storage facility. It is hoped that these measurements can be made to accuracies of +-5 cm and +-2/sup 0/, respectively. The initial phase of this project was primarily a feasibility study. Its principal objective was to evaluate the potential effectiveness of the radar method in the planned canister monitoring application. Its scope included an investigation of the characteristics of radar signals backscattered from waste canisters, a test of preliminary data analysis methods, an assessment of the effects of salt and bentonite (a proposed backfill material) on the propagation of the radar signals, and a review of current ground-penetrating radar technology. A laboratory experiment was performed in which radar signals were backscattered from simulated waste canisters. The radar data were recorded by a digital data acquisition system and were subsequently analyzed by three different computer-based methods to extract estimates of canister location and tilt. Each of these methods yielded results that were accurate within a few centimeters in canister location and within 1/sup 0/ in canister tilt. Measurements were also made to determine the signal propagation velocities in salt and bentonite (actually a bentonite/sand mixture) and to estimate the signal attenuation rate in the bentonite. Finally, a product survey and a literature search were made to identify available ground-penetrating radar systems and alternative antenna designs that may be particularly suitable for this unique application. 10 refs., 21 figs., 4 tabs.

  19. Radar Location Equipment Development Program: Phase I

    Sandness, G.A.; Davis, K.C.

    1985-06-01

    The work described in this report represents the first phase of a planned three-phase project designed to develop a radar system for monitoring waste canisters stored in a thick layer of bedded salt at the Waste Isolation Pilot Plant near Carlsbad, New Mexico. The canisters will be contained in holes drilled into the floor of the underground waste storage facility. It is hoped that these measurements can be made to accuracies of +-5 cm and +-2 0 , respectively. The initial phase of this project was primarily a feasibility study. Its principal objective was to evaluate the potential effectiveness of the radar method in the planned canister monitoring application. Its scope included an investigation of the characteristics of radar signals backscattered from waste canisters, a test of preliminary data analysis methods, an assessment of the effects of salt and bentonite (a proposed backfill material) on the propagation of the radar signals, and a review of current ground-penetrating radar technology. A laboratory experiment was performed in which radar signals were backscattered from simulated waste canisters. The radar data were recorded by a digital data acquisition system and were subsequently analyzed by three different computer-based methods to extract estimates of canister location and tilt. Each of these methods yielded results that were accurate within a few centimeters in canister location and within 1 0 in canister tilt. Measurements were also made to determine the signal propagation velocities in salt and bentonite (actually a bentonite/sand mixture) and to estimate the signal attenuation rate in the bentonite. Finally, a product survey and a literature search were made to identify available ground-penetrating radar systems and alternative antenna designs that may be particularly suitable for this unique application. 10 refs., 21 figs., 4 tabs

  20. Single Bit Radar Systems for Digital Integration

    Bjørndal, Øystein

    2017-01-01

    Small, low cost, radar systems have exciting applications in monitoring and imaging for the industrial, healthcare and Internet of Things (IoT) sectors. We here explore, and show the feasibility of, several single bit square wave radar architectures; that benefits from the continuous improvement in digital technologies for system-on-chip digital integration. By analysis, simulation and measurements we explore novel and harmonic-rich continuous wave (CW), stepped-frequency CW (SFCW) and freque...