Application of QA to R ampersand D support of HLW programs

International Nuclear Information System (INIS)

Ryder, D.E.

1988-01-01

Quality has always been of primary importance in the research and development (R ampersand D) environment. An organization's ability to attract funds for new or continued research is largely dependent on the quality of past performance. However, with the possible exceptions of peer reviews for fund allocation and the referee process prior to publication, past quality assurance (QA) activities were primarily informal good practices. This resulted in standards of acceptable practice that varied from organization to organization. The increasing complexity of R ampersand D projects and the increasing need for project results to be upheld outside the scientific community (i.e., lawsuits and licensing hearings) are encouraging R ampersand D organizations and their clients to adopt more formalized methods for the scientific process and to increase control over support organizations (i.e., suppliers and subcontractors). This has become especially true for R ampersand D organizations involved in the high-level (HLW) projects for a number of years. The PNL began to implement QA program requirements within a few HLW repository preliminary studies in 1978. In 1985, PNL developed a comprehensive QA program for R ampersand D activities in support of two of the proposed repository projects. This QA program was developed by the PNL QA department with a significant amount of support assistance and guidance from PNL upper management, the Basalt Waste Isolation Project (BWIP), and the Salt Repository Program Office (SPRO). The QA program has been revised to add a three-level feature and is currently being implemented on projects sponsored by the Office of Geologic Repositories (DOE/OGR), Repository Technology Program (DOE-CH), Nevada Nuclear Waste Storage Investigation (NNWSI) Project, and other HLW projects

Review of EPRI's steam generator R and D program

International Nuclear Information System (INIS)

Millett, P.J.; Welty, C.J.

1998-01-01

EPRI has carried out an extensive R and D program on SG technology since the mid 1970's. Very early efforts under the auspices of the Steam Generator Owners Group (SGOG) focused on developing remedial actions for the critical SG corrosion issues of denting, wastage and pitting. Fundamental work was also carried out in the development of thermal hydraulic models for vibration and wear, chemical cleaning and tube repair techniques. In the late 1980's and continuing through today, the program has shifted emphasis towards management of steam generator degradation, primarily stress corrosion cracking of the SG tubes on both the primary and secondary sides. The current Steam Generator Management Program (SGMP) carries out R and D in four areas; materials, chemistry, thermal hydraulics and non-destructive testing. The strategic goals of this program and projects put in place to achieve these goals will be reviewed in detail in this paper. (author)

Guide for Conducting Benefit-Cost Evaluation of Realized Impacts of Public R&D Programs

Energy Technology Data Exchange (ETDEWEB)

Ruegg, Rosalie [TIA Consulting, Inc., Emerald Isle, NC (United States); Jordan, Gretchen B. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2011-08-01

This document provides guidance for evaluators who conduct impact assessments to determine the “realized” economic benefits and costs, energy, environmental benefits, and other impacts of the Office of Energy Efficiency and Renewable Energy’s (EERE) R&D programs. The focus of this Guide is on realized outcomes or impacts of R&D programs actually experienced by American citizens, industry, and others. Retrospective evaluations may be contrasted to prospective evaluations that reflect expected or potential outcomes only if assumptions hold. The retrospective approach described in this Guide is based on realized results only and the extent they can be attributed to the efforts of an R&D program. While it has been prepared specifically to guide retrospective benefit-cost analysis of EERE R&D Programs, this report may be used for similar analysis of other public R&D organizations.

THE R AND D PROGRAM FOR TARGETRY AT A NEUTRINO FACTORY

International Nuclear Information System (INIS)

MCDONALD, K.T.; BROWN, K.A.; FINFROCK, C.C.; GASSNER, D.M.; GREENE, G.A.; HANSON, A.L.; KAHN, S.A.; KING, B.J.; KIRK, H.G.; LUDEWIG, H.; PALMER, R.B.; PENDZICK, A.F.; PRIGL, R.; SAMULYAK, R.; SCADUTO, J.; SIMOS, N.; THIEBERGER, P.; TSANG, T.Y.F.; WANG, H.; WEGGEL, R.J.

2001-01-01

The need for intense muon beams for muon colliders [1] and for neutrino factories based on muon storage rings [2,3,4] leads to a concept of 1-4 MW proton beams incident a moving target that is inside a 20-T solenoid magnet, with a mercury jet as a preferred example. Novel technical issues for such a system include disruption of the mercury jet by the proton beam and distortion of the jet on entering the solenoid, as well as more conventional issues of materials lifetime and handling of activated materials in an intense radiation environment. As part of the R and D program [5] of the Neutrino Factory and Muon Collider Collaboration, R and D effort related to targetry is being performed within the context of BNL E951 [6], first results of which are discussed here and in other contributions to this conference

R and D program of the Spanish National Company for Radioactive Wastes management

International Nuclear Information System (INIS)

Astudillo, J.

1993-01-01

The second R+D program of the Spanish National Company for Radioactive Wastes Management (ENRESA) has a whole budget of 56 million $ for the period 1991-1995. This program is included within the Spanish Energy Plan (PEN-91) and encompasses four main areas: 1) Low and medium level radioactive wastes 2) High level radioactive wastes 3) Decommissioning and dismantling of nuclear installations 4) Radiological protection The Spanish program is coordinated with policies of international organizations: CEC,OECD and IAEA

Energy R and D in Japan; TOPICAL

International Nuclear Information System (INIS)

J.J. Dooley

1999-01-01

In 1997, the public and private sectors in Japan invested$90.3 billion in R and D. Japan is the second largest supporter of R and D after the United States. A very large percentage (79.4%) of all R and D in Japan is supported by the private sector. The prolonged economic recession that has plagued the Japanese economy for most of the 1990s has significantly reduced the scale of the Japanese R and D effort compared to what it would have been had the economy been more robust. The Japanese government has recently attempted to bring the economy out of this recession through the use of economic stimulus packages. These stimulus packages have contained significant new funding for R and D, although it is apparent that much of the funding is going to R and D programs and R and D construction projects with very near tern payoff and not to the support of longer term R and D. In 1998, the Japanese government devoted 13.7% of all public R and D funds to the support of energy R and D. The priority accorded to energy R and D in Japan is significantly higher than in any other industrialized nation. The Japanese energy R and D program, which was funded at$2.5 billion in 1997, is overwhelmingly focused on nuclear energy R and D. Nuclear energy R and D (fission and fusion) accounts for 75% of the total national energy R and D budget. The fission energy R and D effort has decreased nearly 24% since 1996 as the government attempts to refocus this program in the face of growing public opposition to the Japanese government's efforts to expand the nuclear power program. Energy efficiency R and D (8% of the total national energy R and D budget) and renewable energy R and D receive relatively modest support from the Japanese government

Matching the $D^{6}R^{4}$ interaction at two-loops

CERN Document Server

D'Hoker, Eric; Pioline, Boris; Russo, Rodolfo

2015-01-01

The coefficient of the $D^6 {\\cal R}^4$ interaction in the low energy expansion of the two-loop four-graviton amplitude in type II superstring theory is known to be proportional to the integral of the Zhang-Kawazumi (ZK) invariant over the moduli space of genus-two Riemann surfaces. We demonstrate that the ZK invariant is an eigenfunction with eigenvalue 5 of the Laplace-Beltrami operator in the interior of moduli space. Exploiting this result, we evaluate the integral of the ZK invariant explicitly, finding agreement with the value of the two-loop $D^6 {\\cal R}^4$ interaction predicted on the basis of S-duality and supersymmetry. A review of the current understanding of the $D^{2p} {\\cal R}^4$ interactions in type II superstring theory compactified on a torus $T^d$ with $p \\leq 3$ and $d \\leq 4$ is included.

US Accelerator R&D Program Toward Intensity Frontier Machines

Energy Technology Data Exchange (ETDEWEB)

Shiltsev, Vladimir [Fermilab

2016-09-15

The 2014 P5 report indicated the accelerator-based neutrino and rare decay physics research as a centerpiece of the US domestic HEP program. Operation, upgrade and development of the accelerators for the near-term and longer-term particle physics program at the Intensity Frontier face formidable challenges. Here we discuss key elements of the accelerator physics and technology R&D program toward future multi-MW proton accelerators.

Nuclear power programs and related R and D topics in Korea

International Nuclear Information System (INIS)

Kang, C. S.

2006-01-01

Full text: Nuclear power generation has assured the stable supply of energy, reduced national trade deficit, lowered electricity bill, and mitigated the air-pollution problem in Korea. As of 2005, Korea has 20 nuclear power plants in operation and 4 under construction. According to the recent 'Long-Term Electricity Supply Scheme', Korea will have 28 nuclear units in operation by 2017, which will consist of 45% of electricity generation. The 3rd 'Comprehensive Promotion Plan of Nuclear Energy' has been completed, which will constitute the national nuclear policy of Korea during the period of 2007 through 2011. According to the Plan, 1,000 MWe-sized OPRIOOO and 1,400 MWe-sized APR1400 will serve for large-scale electricity generation until 2025. Korea will commercialize 330 MWt-sized SMART for multi-use purpose such as seawater desalination, district heating, ship propulsion, and small-scale electricity generation. Korea has joined GIF and INPRO to develop advanced reactor concepts beyond the year of 2025: SFR for fast reactor program and VHTR for hydrogen production. Along with the Plan, the 'Medium and Long Term Nuclear R and D Program (2007-2011)' has been also formulated to support the Plan through systematic R and D work in the areas of: future reactor systems, nuclear safety, nuclear fuel cycles, radiation technology, and innovative nuclear power technology. The total 5-year R and D budget will be a little over 1 billion US dollars

Status of 4-cm-aperture, 17-m-long SSC dipole magnet R ampersand D program at BNL

International Nuclear Information System (INIS)

Devred, A.; Bush, T.; Coombes, R.; DiMarco, J.; Goodzeit, C.; Kuzminski, J.; Puglisi, M.; Radusewicz, P.; Sanger, P.; Schermer, R.; Spigo, G.; Tompkins, J.; Turner, J.; Wolf, Z.; Yu, Y.; Zheng, H.; Ogitsu, T.; Anarella, M.; Cottingham, J.; Ganetis, G; Garber, M.; Ghosh, A.; Greene, A.; Gupta, R.; Herrera, J.; Kahn, S.; Kelly, E.; Meade, A.; Morgan, G.; Muratore, J.; Prodell, A.; Rehak, M.; Rohrer, E.P.; Sampson, W.; Shutt, R.; Thompson, P.; Wanderer, P.; Willen, E.; Bleadon, M.; Hanft, R.; Kuchnir, M.; Mantsch, P.; Mazur, P.O.; Orris, D.; Peterson, T.; Strait, J.; Royet, J.; Scanlan, R.; Taylor, C.

1991-06-01

Over the last year-and-a-half, several 4-cm-aperture, 17-m-long dipole magnet prototypes were built by Brookhaven National Laboratory (BNL) under contract with the Superconducting Super Collider (SSC) Laboratory. These prototypes are the last phase of a half-decade-long R ampersand D program, carried out in collaboration with Fermi National Accelerator Laboratory and Lawrence Berkeley Laboratory, and aimed at demonstrating the feasibility of the SSC main ring dipole magnets. They also prepare the way of the 5-cm-aperture dipole magnet program to be started soon. In this paper, we analyze the mechanical behavior of the BNL prototypes during cool-down and excitation, and we attempt to relate this behavior to the magnet features. The data reveal that the mechanical behavior is sensitive to the vertical collar-yoke interference, and that the magnets exhibited somewhat erratic changes in coil end-loading during cool-down. 9 refs., 6 figs

R-current three-point functions in 4d $\\mathcal{N}=1$ superconformal theories arXiv

CERN Document Server

Manenti, Andrea; Vichi, Alessandro

In 4d $\\mathcal{N}=1$ superconformal field theories (SCFTs) the R-symmetry current, the stress-energy tensor, and the supersymmetry currents are grouped into a single object, the Ferrara--Zumino multiplet. In this work we study the most general form of three-point functions involving two Ferrara--Zumino multiplets and a third generic multiplet. We solve the constraints imposed by conservation in superspace and show that non-trivial solutions can only be found if the third multiplet is R-neutral and transforms in suitable Lorentz representations. In the process we give a prescription for counting independent tensor structures in superconformal three-point functions. Finally, we set the Grassmann coordinates of the Ferrara--Zumino multiplets to zero and extract all three-point functions involving two R-currents and a third conformal primary. Our results pave the way for bootstrapping the correlation function of four R-currents in 4d $\\mathcal{N}=1$ SCFTs.

94-1 R and D program annual operating plan: Fiscal Year 2003

International Nuclear Information System (INIS)

Mason, Richard E.; Dominguez, Pamela D.

2003-01-01

The Laboratory's 94-1 R and D Program is conducted in response to (1) the Defense Nuclear Facilities Safety Board (DNFSB) Recommendation 94-1, 2000-1, and (2) the DNFSB letter to T. J. Glauthier of December 6, 1999, which emphasizes that material stored in a 3013 container must be represented in the Laboratory's Materials Identification and Surveillance (MIS) program. Implementation of the 94-1 R and D Program is the responsibility of the Office of Integration and Disposition. Our program focuses on accelerating the Department of Energy's (DOE's) efforts to reduce health and safety risks to workers, the public, and the environment. Coordinating with the Albuquerque Nuclear Materials Stewardship Office, the Office of Integration of Deposition continues to direct activities under this project that involve the development of stabilization technologies. This program also maintains the viability of the 3013 standard, Section 6, which requires that materials are represented in the MIS inventory. The 94-1 R and D Program focuses on developing the technical basis for stabilizing and safely storing plutonium-bearing materials. To address these issues, we have in place a material identification and stabilization project, a surveillance and monitoring project, and a management team

Neutrino Factory and Muon Collider Collaboration R and D Program

International Nuclear Information System (INIS)

Zisman, M.S.

2000-01-01

The Neutrino Factory and Muon Collider Collaboration (MC) comprises some 140 scientists and engineers located at U.S. National Laboratories and Universities, and at a number of non-U.S. research institutions. In the past year, the MC R and D program has shifted its focus mainly toward the design issues related to the development of a Neutrino Factory based on a muon storage ring. In this paper the status of the various R and D activities is described, and future plans are outlined

Maximizing DOE R and D efforts in tru waste management learning from international programs

International Nuclear Information System (INIS)

Saxman, P.A.; Loughead, J.S.C.

1990-01-01

Through the International Technology Exchange Program, Department of Energy (DOE) technical specialists maintain a formal dialogue with research and Development (R and D) specialists from nuclear programs in other countries. The objective of these exchanges is to seek innovative waste management solutions, maximize progress for ongoing R and D activities, and minimize the development time required for implementation of transuranic (TRU) waste processing technologies and waste assay developments. Based on information provided by PNC during the exchange, DOE specialists evaluated PNC's efforts to implement technologies and techniques from their R and D program activities. This paper presents several projects with particular potential for DOE operations, and suggests several ways that these concepts could be used to advantage by DOE or commercial programs

NRCan's hydrogen storage R and D program

International Nuclear Information System (INIS)

Scepanovic, V.

2004-01-01

'Full text:' Natural Resources Canada (NRCan) has been working in partnership with industry, other government departments and academia to expedite the development of hydrogen technologies. NRCan's Hydrogen and Fuel Cell R and D Program covers all aspects of hydrogen technologies: production, storage, utilization and codes and standards. Hydrogen storage is a key enabling technology for the advancement of fuel cell power systems in transportation, stationary, and portable applications. NRCan's storage program has been focused on developing storage materials and technologies for a range of applications with the emphasis on transportation. An overview of most recent hydrogen storage projects including pressurized hydrogen, liquid hydrogen and storage in hydrides and carbon-based materials will be given. (author)

Overview of Evaluation Methods for R&D Programs. A Directory of Evaluation Methods Relevant to Technology Development Programs

Energy Technology Data Exchange (ETDEWEB)

Ruegg, Rosalie [TIA Consulting, Inc., Emeral Isle, NC (United States); Jordan, Gretchen B. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2007-03-01

This document provides guidance for evaluators who conduct impact assessments to determine the “realized” economic benefits and costs, energy, environmental benefits, and other impacts of the Office of Energy Efficiency and Renewable Energy’s (EERE) R&D programs. The focus of this Guide is on realized outcomes or impacts of R&D programs actually experienced by American citizens, industry, and others.

Thermal-hydraulic R and D infrastructure for water cooled reactors of the Indian nuclear power program

International Nuclear Information System (INIS)

Vijayan, P.K.; Jain, V.; Saha, D.; Sinha, R.K.

2009-01-01

R and D has been the critical ingredient of Indian Nuclear Power Program from the very inception. Approach to R and D infrastructure has been closely associated with the three-stage nuclear power program that was crafted on the basis of available resources and technology in the short-term and energy security in the long-term. Early R and D efforts were directed at technologies relevant to Pressurized Heavy Water Reactors (PHWRs) which are currently the mainstay of Indian nuclear power program. Lately, the R and D program has been steered towards the design and development of advanced and innovative reactors with the twin objective of utilization of abundant thorium and to meet the future challenges to nuclear power such as enhanced safety and reliability, better economy, proliferation resistance etc. Advanced Heavy Water Reactor (AHWR) is an Indian innovative reactor currently being developed to realize the above objectives. Extensive R and D infrastructure has been created to validate the system design and various passive concepts being incorporated in the AHWR. This paper provides a brief review of R and D infrastructure that has been developed at Bhabha Atomic Research Centre for thermal-hydraulic investigations for water-cooled reactors of Indian nuclear power program. (author)

The R+D radiological protection program in the European Communities

International Nuclear Information System (INIS)

Mingot Buades, F.

1993-01-01

The R+D program a radiological protection for the year 1992 has lied basically on three areas: I .- Radiological exposure of man II .- Radiation effects on man (evaluation, prevention and treatment) III.- Risks and management of radiation exposure

Development of Capacity Building Training Programs for Nuclear R and D Personnel

International Nuclear Information System (INIS)

Lee, Eui Jin; Nam, Youngmi; Hwang, Hyeseon; Jang, Eunsook; Song, Eun Ju

2016-01-01

The Nuclear Training and Education Center of the Korea Atomic Energy Research Institute has been operating technical training courses on nuclear engineering, engineering mathematics, management leadership training, out sourced practical training, legal education, etc. Strengthening nuclear R and D capacity is essential for the long-term mission and goals of the institute. Therefore, it requires a comprehensive training program to strengthen the unique capability of the institute that reflects diversity and differentiation. In this regard, the capacity building training program has developed on a modular basis, and the developed training program should be tailored to operate according to the institute needs. The capacity building training program for nuclear R and D personnel was developed to reflect the technology strengths of the institute. The developed training program will be developed into a leading branded education of the institute in the future

Development of Capacity Building Training Programs for Nuclear R and D Personnel

Energy Technology Data Exchange (ETDEWEB)

Lee, Eui Jin; Nam, Youngmi; Hwang, Hyeseon; Jang, Eunsook; Song, Eun Ju [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

2016-10-15

The Nuclear Training and Education Center of the Korea Atomic Energy Research Institute has been operating technical training courses on nuclear engineering, engineering mathematics, management leadership training, out sourced practical training, legal education, etc. Strengthening nuclear R and D capacity is essential for the long-term mission and goals of the institute. Therefore, it requires a comprehensive training program to strengthen the unique capability of the institute that reflects diversity and differentiation. In this regard, the capacity building training program has developed on a modular basis, and the developed training program should be tailored to operate according to the institute needs. The capacity building training program for nuclear R and D personnel was developed to reflect the technology strengths of the institute. The developed training program will be developed into a leading branded education of the institute in the future.

R&D Proposal for the National Muon Acccelerator Program

Energy Technology Data Exchange (ETDEWEB)

2010-02-01

This document contains a description of a multi-year national R&D program aimed at completing a Design Feasibility Study (DFS) for a Muon Collider and, with international participation, a Reference Design Report (RDR) for a muon-based Neutrino Factory. It also includes the supporting component development and experimental efforts that will inform the design studies and permit an initial down-selection of candidate technologies for the ionization cooling and acceleration systems. We intend to carry out this plan with participants from the host national laboratory (Fermilab), those from collaborating U.S. national laboratories (ANL, BNL, Jlab, LBNL, and SNAL), and those from a number of other U.S. laboratories, universities, and SBIR companies. The R&D program that we propose will provide the HEP community with detailed information on future facilities based on intense beams of muons - the Muon Collider and the Neutrino Factory. We believe that these facilities offer the promise of extraordinary physics capabilities. The Muon Collider presents a powerful option to explore the energy frontier and the Neutrino Factory gives the opportunity to perform the most sensitive neutrino oscillation experiments possible, while also opening expanded avenues for the study of new physics in the neutrino sector. The synergy between the two facilities presents the opportunity for an extremely broad physics program and a unique pathway in accelerator facilities. Our work will give clear answers to the questions of expected capabilities and performance of these muon-based facilities, and will provide defensible ranges for their cost. This information, together with the physics insights gained from the next-generation neutrino and LHC experiments, will allow the HEP community to make well-informed decisions regarding the optimal choice of new facilities. We believe that this work is a critical part of any broad strategic program in accelerator R&D and, as the P5 panel has recently

R&D PROPOSAL FOR THE NATIONAL MUON ACCELERATOR PROGRAM

Energy Technology Data Exchange (ETDEWEB)

Muon Accelerator Program; Zisman, Michael S.; Geer, Stephen

2010-02-24

This document contains a description of a multi-year national R&D program aimed at completing a Design Feasibility Study (DFS) for a Muon Collider and, with international participation, a Reference Design Report (RDR) for a muon-based Neutrino Factory. It also includes the supporting component development and experimental efforts that will inform the design studies and permit an initial down-selection of candidate technologies for the ionization cooling and acceleration systems. We intend to carry out this plan with participants from the host national laboratory (Fermilab), those from collaborating U.S. national laboratories (ANL, BNL, Jlab, LBNL, and SNAL), and those from a number of other U.S. laboratories, universities, and SBIR companies. The R&D program that we propose will provide the HEP community with detailed information on future facilities based on intense beams of muons--the Muon Collider and the Neutrino Factory. We believe that these facilities offer the promise of extraordinary physics capabilities. The Muon Collider presents a powerful option to explore the energy frontier and the Neutrino Factory gives the opportunity to perform the most sensitive neutrino oscillation experiments possible, while also opening expanded avenues for the study of new physics in the neutrino sector. The synergy between the two facilities presents the opportunity for an extremely broad physics program and a unique pathway in accelerator facilities. Our work will give clear answers to the questions of expected capabilities and performance of these muon-based facilities, and will provide defensible ranges for their cost. This information, together with the physics insights gained from the next-generation neutrino and LHC experiments, will allow the HEP community to make well-informed decisions regarding the optimal choice of new facilities. We believe that this work is a critical part of any broad strategic program in accelerator R&D and, as the P5 panel has recently

Evaluating Realized Impacts of DOE/EERE R&D Programs. Standard impact evaluation method

Energy Technology Data Exchange (ETDEWEB)

Ruegg, Rosalie [TIA Consulting, Inc. (United States); O' Connor, Alan C. [RTI International, Research Triangle Park, NC (United States); Loomis, Ross J. [RTI International, Research Triangle Park, NC (United States)

2014-08-01

This document provides guidance for evaluators who conduct impact assessments of research and development (R&D) programs for the U.S. Department of Energy’s (DOE) Office of Energy Efficiency and Renewable Energy (EERE). It is also targeted at EERE program staff responsible for initiating and managing commissioned impact studies. The guide specifies how to estimate economic benefits and costs, energy saved and installed or generated, environmental impacts, energy security impacts, and knowledge impacts of R&D investments in advanced energy technologies.

Financing R&D Projects in Southern Italy: The “Technological Vouchers and Cooperative Research” Program

Directory of Open Access Journals (Sweden)

Gianpaolo Iazzolino

2013-09-01

Full Text Available The paper deals with the evaluation and financing of research and innovation projects. The paper analyzes and discusses the “Technological Vouchers and Cooperative Research” program in the Calabria Region (Southern Italy, as a program for financing R&D projects in a geographical area far behind in development. Three real cases of R&D projects are described. The program was effective as regards the stimulus to realizing R&D activities by Calabrian SMEs and furthermore in relation to the improvement of cooperation between SMEs, research centers, universities and technological laboratories. The weak points of the program mainly regard the evaluation phase that made it impossible to get a feedback useful for policy and for driving future agenda.

Geant4-related R&D for new particle transport methods

CERN Document Server

Augelli, M; Evans, T; Gargioni, E; Hauf, S; Kim, C H; Kuster, M; Pia, M G; Filho, P Queiroz; Quintieri, L; Saracco, P; Santos, D Souza; Weidenspointner, G; Zoglauer, A

2009-01-01

A R&D project has been launched in 2009 to address fundamental methods in radiation transport simulation and revisit Geant4 kernel design to cope with new experimental requirements. The project focuses on simulation at different scales in the same experimental environment: this set of problems requires new methods across the current boundaries of condensed-random-walk and discrete transport schemes. An exploration is also foreseen about exploiting and extending already existing Geant4 features to apply Monte Carlo and deterministic transport methods in the same simulation environment. An overview of this new R&D associated with Geant4 is presented, together with the first developments in progress.

4D Art: corps réels et virtuels, une réalité augmentée

Directory of Open Access Journals (Sweden)

Michel Lemieux

2016-05-01

Full Text Available La compagnie canadienne 4D Art surprend le regard du public et interroge les sens de réalité et présence, par l’interaction scénique de corps réels et virtuels en mouvement. Pour comprendre le processus créateur des spectacles de 4D Art, on présente un entretien inédit réalisé avec les directeurs artistiques Michel Lemieux et Victor Pilon. Les motivations artistiques du jeu réel et virtuel, les procédés employés dans la création des figures virtuelles et les défis vécus par les acteurs sont exposés par les créateurs.

National/international R and D programs on uranium mill tailings

International Nuclear Information System (INIS)

Hamel, P.E.

1981-05-01

The mining and milling of uranium ores results in the production of large quantities of wastes containing low concentrations of radionuclides such as uranium, thorium, radium, radon and their daughter products. The current concern of the regulatory authorities is with the extent of the problems and the disposal methods that must be required now to ensure that an acceptable level of protection is maintained in the long term. This concern is the subject of a number of R and D programs. In Canada, the Technical Planning Group on Uranium Tailings was established to review ongoing activities and to plan a research program on the management of wastes after the mine and mill have shut down. The Group has completed its review and a report containing its conclusions and recommendations for a proposed national R and D program has been prepared. Included is a proposal for a centralized organizational structure for the coordination and managment of the total program which is to be supported jointly by the federal government, two (Ontario, Saskatchewan) provincial governments, and uranium producers. At the international level, the Nuclear Energy Agency originated, in 1979, a program to study the extent of the long-term problems of uranium mill tailings, and to develop an internationally acceptable methodology for making rational decisions regarding their long-term management taking into account the ICRP principles and system of dose limitation

Seminar on R + D work and studies on the disposal and final storage of radioactive waste

International Nuclear Information System (INIS)

1979-10-01

The Seminar had following goals: The research- and development works for safeguarding and final storage of waste are discussed and gone through with regard to their complete processing in due time. A survey on possible co-operation in R+D work is to be set up. The PTB (Physical-technical federal organisation) can normally not order any R+D work nor can it financially support them; it will, however support necessary R+D works with all possibilities it has, for example by sending letters of recommendation and agreement to ministries and other competent institutions. For special investigations relevant for the permission, there are also own means in restricted volume available. (orig./HP) 891 HP/orig.- 892 HIS [de

The middle ground of the NDE R and D spectrum

International Nuclear Information System (INIS)

Burte, H.M.; Chimenti, D.E.; Thompson, D.O.; Thompson, R.B.

1983-01-01

This keynote talk attempts to call attention to the interdisciplinary nature of NDE (nondestructive evaluation) science and technology and introduce some approaches for fostering R and D in such a situation. The objectives of DARPA, the Air Force core program for developing a science base for NDE are described. Finally, several exploratory development programs are investigated. The needs addressed by NDE include performance demands, safety, conservation, productivity with quality, and minimization of life cycle costs. The science base for electromagnetic techniques includes eddy-current flaw interactions, inversion techniques, and probe figures-of-merit. The problem of inspection reliability is addressed, and an accept-reject methodology schematicized. A methodology for approaching the middle ground of the NDE R and D spectrum is outlined. Finally, future possibilities such as the characterization of flaws in ceramics, transducer understanding, new electromagnetic probes, and thermal wave imaging are also discussed

CANDU advanced fuel R and D programs for 1997 - 2006 in Korea

International Nuclear Information System (INIS)

Suk, H.C.; Yang, M.S.; Sim, K-S.; Yoo, K.J.

1997-01-01

KAERI has a comprehensive product development program of CANFLEX and DUPIC fuels to introduce them into CANDU reactors in Korea and a clear vision of how the product will evolve over the next 10 years. CANDU reactors are not the majority of nuclear power plants in Korea, but they produce significant electricity to contribute Korea's economic growth as well as to satisfy the need for energy. The key targets of the development program are safety enhancement, reduction of spent fuel volume, and economic improvements, using the inherent characteristics and advantages of CANDU technology The CANFLEX and DUPIC R and D programs are conducted currently under the second stage of Korea's Nuclear Energy R and D Project as a national mid- and long-term program over the next 10 years from 1997 to 2006. The specific activities of the programs have taken account of the domestic and international environment concerning on non-proliferation in the Peninsula of Korea. As the first of the development products in the short-term, the CANFLEX-NU fuel will be completely developed jointly by KAERI/AECL and will be useful for the older CANDU-6 Wolsong unit 1. As the second product, the CANFLEX-0.9 % equivalent SEU fuel is expected to be completely developed within the next decade. It will be used in CANDU-6 reactors in Korea immediately after the development, if the existing RU in the world is price competitive with natural uranium. The DUPIC R and D program, as a long term program, is expected to demonstrate the possibility of use of used PWR fuel in CANDU reactors in Korea during the next 10 years. The pilot scale fabrication facility would be completed around 2010. (author)

CANDU advanced fuel R and D programs for 1997 - 2006 in Korea

Energy Technology Data Exchange (ETDEWEB)

Suk, H.C.; Yang, M.S.; Sim, K-S.; Yoo, K.J. [Korea Atomic Energy Research Inst., Yusong, Taejon (Korea, Republic of)

1997-07-01

KAERI has a comprehensive product development program of CANFLEX and DUPIC fuels to introduce them into CANDU reactors in Korea and a clear vision of how the product will evolve over the next 10 years. CANDU reactors are not the majority of nuclear power plants in Korea, but they produce significant electricity to contribute Korea's economic growth as well as to satisfy the need for energy. The key targets of the development program are safety enhancement, reduction of spent fuel volume, and economic improvements, using the inherent characteristics and advantages of CANDU technology The CANFLEX and DUPIC R and D programs are conducted currently under the second stage of Korea's Nuclear Energy R and D Project as a national mid- and long-term program over the next 10 years from 1997 to 2006. The specific activities of the programs have taken account of the domestic and international environment concerning on non-proliferation in the Peninsula of Korea. As the first of the development products in the short-term, the CANFLEX-NU fuel will be completely developed jointly by KAERI/AECL and will be useful for the older CANDU-6 Wolsong unit 1. As the second product, the CANFLEX-0.9 % equivalent SEU fuel is expected to be completely developed within the next decade. It will be used in CANDU-6 reactors in Korea immediately after the development, if the existing RU in the world is price competitive with natural uranium. The DUPIC R and D program, as a long term program, is expected to demonstrate the possibility of use of used PWR fuel in CANDU reactors in Korea during the next 10 years. The pilot scale fabrication facility would be completed around 2010. (author)

R and D PROPOSAL FOR THE NATIONAL MUON ACCELERATOR PROGRAM

International Nuclear Information System (INIS)

Zisman, Michael S.; Geer, Stephen

2010-01-01

This document contains a description of a multi-year national R and amp;D program aimed at completing a Design Feasibility Study (DFS) for a Muon Collider and, with international participation, a Reference Design Report (RDR) for a muon-based Neutrino Factory. It also includes the supporting component development and experimental efforts that will inform the design studies and permit an initial down-selection of candidate technologies for the ionization cooling and acceleration systems. We intend to carry out this plan with participants from the host national laboratory (Fermilab), those from collaborating U.S. national laboratories (ANL, BNL, Jlab, LBNL, and SNAL), and those from a number of other U.S. laboratories, universities, and SBIR companies. The R and D program that we propose will provide the HEP community with detailed information on future facilities based on intense beams of muons--the Muon Collider and the Neutrino Factory. We believe that these facilities offer the promise of extraordinary physics capabilities. The Muon Collider presents a powerful option to explore the energy frontier and the Neutrino Factory gives the opportunity to perform the most sensitive neutrino oscillation experiments possible, while also opening expanded avenues for the study of new physics in the neutrino sector. The synergy between the two facilities presents the opportunity for an extremely broad physics program and a unique pathway in accelerator facilities. Our work will give clear answers to the questions of expected capabilities and performance of these muon-based facilities, and will provide defensible ranges for their cost. This information, together with the physics insights gained from the next-generation neutrino and LHC experiments, will allow the HEP community to make well-informed decisions regarding the optimal choice of new facilities. We believe that this work is a critical part of any broad strategic program in accelerator R and D and, as the P5 panel has

R and D Proposal for the National Muon Acccelerator Program

International Nuclear Information System (INIS)

2010-01-01

This document contains a description of a multi-year national R and D program aimed at completing a Design Feasibility Study (DFS) for a Muon Collider and, with international participation, a Reference Design Report (RDR) for a muon-based Neutrino Factory. It also includes the supporting component development and experimental efforts that will inform the design studies and permit an initial down-selection of candidate technologies for the ionization cooling and acceleration systems. We intend to carry out this plan with participants from the host national laboratory (Fermilab), those from collaborating U.S. national laboratories (ANL, BNL, Jlab, LBNL, and SNAL), and those from a number of other U.S. laboratories, universities, and SBIR companies. The R and D program that we propose will provide the HEP community with detailed information on future facilities based on intense beams of muons - the Muon Collider and the Neutrino Factory. We believe that these facilities offer the promise of extraordinary physics capabilities. The Muon Collider presents a powerful option to explore the energy frontier and the Neutrino Factory gives the opportunity to perform the most sensitive neutrino oscillation experiments possible, while also opening expanded avenues for the study of new physics in the neutrino sector. The synergy between the two facilities presents the opportunity for an extremely broad physics program and a unique pathway in accelerator facilities. Our work will give clear answers to the questions of expected capabilities and performance of these muon-based facilities, and will provide defensible ranges for their cost. This information, together with the physics insights gained from the next-generation neutrino and LHC experiments, will allow the HEP community to make well-informed decisions regarding the optimal choice of new facilities. We believe that this work is a critical part of any broad strategic program in accelerator R and D and, as the P5 panel has

Overview of materials R and D for fusion and Gen-4

Energy Technology Data Exchange (ETDEWEB)

Kohyama, A. [Kyoto Univ., lnstitute of Advanced Energy (Japan); Tavassoli, F.; Carre, F.; Billot, P. [CEA Saclay, 91 - Gif sur Yvette (France); Zinide, S. [Oak Ridge National Laboratory, Materials Science and Technology Div., AK TN (United States)

2007-07-01

Full text of publication follows: In view of the growing need for energy, the risk of exhaustion of fossil fuel and the problem of global warming, the nuclear energy is receiving added attention as a realistic and viable advanced solution. International collaborations on Generation IV (Gen-IV) fission reactors and on ITER and DEMO fusion reactors are developing. This is particularly the case in the sector of materials, where they hold the key to success of these systems. The international community has recognized and planned its materials R and D work for Fusion and Gen-IV reactors with the following considerations: 1- The time allotted to materials R and D is short and may not allow development of totally new materials. 2- Activities required, to cover existing materials variations and service conditions necessary for reactor design, are very time consuming. 3- The work to be done must build upon the existing knowledge of materials and avoid duplications. Although ITER for fusion and Generation four International Forum (GIF) for Gen-IV are important international collaborative programs, they are insufficient to meet all the national energy policies of the participating countries. This paper provides an overview of the materials R and D carried out for fusion and Gen-IV reactors at international and national levels. Materials programs discussed include both cross-cutting and reactor specific actions, where major tasks can be defined as: + Cross-cutting materials tasks: - materials for high temperature service; - materials with neutron damage tolerance; - materials behavior analysis and modeling; - high temperature design methodology. + Reactor specific materials tasks: - very high temperature alloys; - carbon, high temperature ceramics and their composites; - materials compatibilities. Starting with a brief introduction of materials R and D strategies, ITER and Broader Approach (BA), overall activities for fusion and GIF for Gen-IV will be reviewed. Domestic

R and D limited partnerships (possible applications in advanced communications satellite technology experiment program)

Science.gov (United States)

1985-01-01

Typical R&D limited partnership arrangements, advantages and disadvantages of R&D limited partnership (RDLPs) and antitrust and tax implications are described. A number of typical forms of RDLPs are described that may be applicable for use in stimulating R&D and experimental programs using the advanced communications technology satellite. The ultimate goal is to increase the rate of market penetration of goods and/or services based upon advanced satellite communications technology. The conditions necessary for these RDLP forms to be advantageous are outlined.

Safety approach and R and D program for future french sodium-cooled fast reactors

International Nuclear Information System (INIS)

Beils, Stephane; Carluec, Bernard; Devictor, Nicolas; Fiorini, Gian Luigi; Sauvage, Jean Francois

2011-01-01

This paper presents briefly the safety approach as well as the R and D program that is underway to support the deployment of future French Sodium-Cooled fast Reactors (SFRs): A) Safety objectives and principles for future reactors. The content of the first section reflects the works of AREVA, CEA, and EDF concerning the safety orientations for the future reactors. The availability of such orientations and requirements for the SFRs has to allow introducing and managing the process that will lead to the detailed definition of the safety approach, to the selection of the corresponding safety options, and to the identification and motivation of the supporting R and D. B) Strategy and roadmap in support of the R and D for future SFRs. This section describes the R and D program led jointly by CEA, EDF, and AREVA, which has been developed with the objectives to be able to preliminarily define, by 2012, the safety orientations for the future SFRs, and to deduce from them the characteristics of the ASTRID prototype. (author)

R&D PROPOSAL FOR THE NATIONAL MUON ACCELERATOR PROGRAM

OpenAIRE

Zisman, Michael S.

2011-01-01

This document contains a description of a multi-year national R&D program aimed at completing a Design Feasibility Study (DFS) for a Muon Collider and, with international participation, a Reference Design Report (RDR) for a muon-based Neutrino Factory. It also includes the supporting component development and experimental efforts that will inform the design studies and permit an initial down-selection of candidate technologies for the ionization cooling and acceleration systems. We intend to ...

Programming scheme based optimization of hybrid 4T-2R OxRAM NVSRAM

Science.gov (United States)

Majumdar, Swatilekha; Kingra, Sandeep Kaur; Suri, Manan

2017-09-01

In this paper, we present a novel single-cycle programming scheme for 4T-2R NVSRAM, exploiting pulse engineered input signals. OxRAM devices based on 3 nm thick bi-layer active switching oxide and 90 nm CMOS technology node were used for all simulations. The cell design is implemented for real-time non-volatility rather than last-bit, or power-down non-volatility. Detailed analysis of the proposed single-cycle, parallel RRAM device programming scheme is presented in comparison to the two-cycle sequential RRAM programming used for similar 4T-2R NVSRAM bit-cells. The proposed single-cycle programming scheme coupled with the 4T-2R architecture leads to several benefits such as- possibility of unconventional transistor sizing, 50% lower latency, 20% improvement in SNM and ∼20× reduced energy requirements, when compared against two-cycle programming approach.

IMPLEMESTASI E-KRS PADA PROGRAM STUDI D4 TEKNIK INFORMATIKA

Directory of Open Access Journals (Sweden)

Chairul Fikri Ramadhan

2016-08-01

Full Text Available Seiring dengan kemajuan ilmu pengetahuan dan teknologi, komputer telah digunakan untuk berbagai keperluan dan menjadi bagian yang sangat penting untuk menunjang aktifitas maupun pekerjaan dalam segala hal. Pemanfaatan atau pengembangan sistem komputer ini sangat membantu pekerjaan seseorang termasuk dalam kegiatan akademik. Termasuk pula perguruan tinggi Politeknik Harapan Bersama Tegal, khususnya Program Studi D4 Teknik Informatika. Pada setiap perguruan tinggi tentunya memiliki system pengisian KRS sebagai syarat untuk mengambil matakuliah yang akan ditempuh disemester depan. Namun banyak perguruan tinggi yang masih menggunakan sistem pengisian KRS dengan cara manual termasuk pada Program Studi D4 Teknik Informatika Politeknik Harapan Bersama Tegal.Berdasarkan kondisi tersebut, maka diperlukan perencanaan sebagai langkah awal, menganalisis data yang diperlukan, merancang sistem yang ada menggunakan UML, serta penerapannya untuk mengimplementasikan  sebuah sistem E-KRS pada program studi D4 Teknik Informatika dengan tujuan untuk menghasilkan sebuah aplikasi E-KRS pada Program Studi D4 Teknik Informatika sehingga mempermudah mahasiswa dalam mengisi formulir KRS secara online. Sistem dirancang dan dibangun dengan menggunakan teknologi PHP serta Framework Code Igniter, Xampp sebagai web server, MySql sebagai database server. Dan Adobe Dreamweaver sebagai editor. Kata kunci: Tegal, E-KRS, Program Studi D4 Teknik Informatika

HLW disposal in Germany - R and D achievements and outlook

International Nuclear Information System (INIS)

Steininger, W.

2006-01-01

The paper gives a brief overview of the status of R and D on HLW disposal. Shortly addressed is the current nuclear policy. After describing the responsibilities regarding R and D for disposing of heat-generating high-level (HLW) waste (vitrified waste and spent fuel), selected projects are mentioned to illustrate the state of knowledge in disposing of waste in rock salt. Participation in international projects and programs is described to illustrate the value for the German concepts and ideas for HLW disposal in different rock types. Finally, a condensed outlook on future activities is given. (author)

FERMILAB ACCELERATOR R&D PROGRAM TOWARDS INTENSITY FRONTIER ACCELERATORS : STATUS AND PROGRESS

Energy Technology Data Exchange (ETDEWEB)

Shiltsev, Vladimir [Fermilab

2016-11-15

The 2014 P5 report indicated the accelerator-based neutrino and rare decay physics research as a centrepiece of the US domestic HEP program at Fermilab. Operation, upgrade and development of the accelerators for the near- term and longer-term particle physics program at the Intensity Frontier face formidable challenges. Here we discuss key elements of the accelerator physics and technology R&D program toward future multi-MW proton accelerators and present its status and progress. INTENSITY FRONTIER ACCELERATORS

Nuclear R and D program in Indonesia and selection of future research reactor to support it

International Nuclear Information System (INIS)

Baiquni, A.; Subki, I.

1981-01-01

The nuclear R and D program selection decision is described as a phased program, each phase having its specific objective. The elements of each phase are identified and related with the objective, from which the activities of each element are also broadly outlined. To support the nuclear R and D program and to realize the objectives in each phase, the research facilities are also developed. A new nuclear development center housing a multipurpose reactor (MPR) and various laboratories are also described. The choice of the MPR and its criteria are also described briefly

FY2016 Advanced Batteries R&D Annual Progress Report - Part 4 of 5

Energy Technology Data Exchange (ETDEWEB)

None, None

2017-08-31

The Advanced Batteries research and development (R&D) subprogram within the DOE Vehicle Technologies Office (VTO) provides support and guidance for projects focusing on batteries for plug-in electric vehicles. Program targets focus on overcoming technical barriers to enable market success including: (1) significantly reducing battery cost, (2) increasing battery performance (power, energy, durability), (3) reducing battery weight & volume, and (4) increasing battery tolerance to abusive conditions such as short circuit, overcharge, and crush. This report describes the progress made on the research and development projects funded by the Battery subprogram in 2016. This section covers Advanced Battery Materials Research (BMR) part 1.

X-ray M4,5 Resonant Raman Scattering from La metal with final 4p hole: Calculations with 4p-4d-4f configuration interaction in the final state and comparison with the experiment

International Nuclear Information System (INIS)

Taguchi, M.; Braicovich, L.; Tagliaferri, A.; Dallera, C.; Giarda, K.; Ghiringhelli, G.; Brookes, N.B.; Borgatti, F.

2001-03-01

We consider the X-Ray Resonant Raman Scattering (RRS) in La in the whole M 4,5 region ending with a state with a 4p hole, along the sequence 3d 10 4f 0 →3d 9 4f 1 →3d 10 4p 5 4f 1 . The final state configuration mixes with that with two 4d holes i.e. 3d 10 4d 8 4f n+2 having almost the same energy. Thus RRS must be described by introducing final state Configuration Interaction (CI) between states with one 4p hole and with two 4d holes. This approach allows detailed experimental data on La-metal to be interpreted on the basis of a purely ionic approach. It is shown that the inclusion of CI is crucial and has very clear effects. The calculations with the Kramers-Heisenberg formula describe all measured spectral features appearing in the strict Raman regime i.e. dispersing with the incident photon energy. In the experiment also a nondispersive component is present when the excitation energy is greater than about 2 eV above the M 5 peak. The shape and position of this component is well accounted for by a model based on all possible partitions of the excitation energy between localised and extended states. However, the intensity of the nondispersive component is greater in the measurements, suggesting a rearrangement in the intermediate excited state. The comparison of ionic calculations with the metal measurements is legitimate, as shown by the comparison between the measurements on La-metal and on LaF 3 with M 5 excitation, giving the same spectrum within the experimental accuracy. Moreover, the experiment shows that the final lifetime broadening is much greater in the final states corresponding to lower outgoing photon energies than in the states corresponding to higher outgoing photon energies. (author)

Overview of the X-band R and D Program

International Nuclear Information System (INIS)

2002-01-01

An electron/positron linear collider with a center-of-mass energy between 0.5 and 1 TeV is recognized as an important complement to the physics program of the LHC. The Next Linear Collider (NLC) is being designed by a US collaboration (FNAL, LBNL, LLNL, and SLAC) which is working closely with the Japanese collaboration that is designing the Japanese Linear Collider (JLC). The NLC/JLC main linacs are based on normal conducting 11 GHz rf. This paper will discuss the status of the NLC design. Results from the ongoing R and D programs, including the recently uncovered high gradient damage problem, will be discussed along with changes to the optical design and collider layout which were made to enhance the collider capabilities

Heavy water production benefits of a supporting r and d program

International Nuclear Information System (INIS)

Bancroft, A.R.; Chuang, K.T.; Dalrymple, D.G.

1981-01-01

Considerable economic benefit was obtained from an active R and D program while the Canadian heavy water plants were brought to mature operation during the 1970s. The introduction to Canada of this new chemical processing industry led to unexpected process, equipment and materials problems. Having a small team of technical experts already working on heavy water processes and a much larger R and D team working in related fields allowed a rapid response to the problems that limited production. The number of engineers and scientists working on the GS process rose rapidly from a skeleton team in 1970 to 54 during 1974. Effort declined steadily as the major problems were solved and reached 22 by 1980. Cumulative effort over the decade was 264 man-years at a cost of 3.3 percent of the value of the heavy water produced. The new production benefits have lagged behind the R and D expenditure by a few years and the current spending rate is 1.2 percent of product value. Important contributions were made in the areas of process simulation, process chemistry, materials of construction, sieve trays, and mechanical equipment

The Effects of State R&D Tax Credits in Stimulating Private R&D Expenditure: A Cross-State Empirical Analysis

Science.gov (United States)

Wu, Yonghong

2005-01-01

This is a cross-state empirical study which examines the effects of state research and development (R&D) tax credits on private R&D expenditure in the states. Other explanatory variables include federal R&D subsidies, public services in higher education and R&D-targeted programs as well as other control variables. The statistical result shows that…

Magnet R and D for the US LHC Accelerator Research Program (LARP)

International Nuclear Information System (INIS)

Gourlay, S.A.; Ambrosio, G.; Andreev, N.; Anerella, M.; Barzi, E.; Bossert, R.; Caspi, S.; Dietderich, D.R.; Ferracin, P.; Gupta, R.; Ghosh, A.; Hafalia, A.R.; Hannaford, C.R.; Harrison, M.; Kashikhin, V.S.; Kashikhin, V.V.; Lietzke, A.F.; Mattafirri, S.; McInturff, A.D.; Nobrega, F.; Novitsky, I.; Sabbi, G.L.; Schmazle, J.; Stanek, R.; Turrioni, D.; Wanderer, P.; Yamada, R.; Zlobin, A.V.

2006-01-01

In 2004, the US DOE established the LHC Accelerator Research Program (LARP) with the goal of developing a technology base for future upgrades of the LHC. The focus of the magnet program, which is a collaboration of three US laboratories, BNL, FNAL and LBNL, is on development of high gradient quadrupoles using Nb 3 Sn superconductor. Other program components address issues regarding magnet design, radiation-hard materials, long magnet scale-up, quench protection, fabrication techniques and conductor and cable R and D. This paper presents an overall view of the program with emphasis on the current quadrupole project and outlines the long-term goals of the program

The Canadian R and D program targeted at CANDU reactors

International Nuclear Information System (INIS)

Moeck, E.O.

1988-01-01

CANDU reactors produce electricity cheaply and reliably, with miniscule risk to the population and minimal impact on the environment. About half of Ontario's electricity and a third of New Brunswick's are generated by CANDU power plants. Hydro Quebec and utilities in Argentina, India, Pakistan, and the Republic of Korea also successfully operate CANDU reactors. Romania will soon join their ranks. The proven record of excellent performance of CANDUs is due in part to the first objective of the vigorous R and D program: namely, to sustain and improve existing CANDU power-plant technology. The second objective is to develop improved nuclear power plants that will remain competitive compared with alternative energy supplies. The third objective is to continue to improve our understanding of the processes underlying reactor safety and develop improved technology to mitigate the consequences of upset conditions. These three objectives are addressed by individual R and D programs in the areas of CANDU fuel channels, reduced operating costs, reduced capital costs, reactor safety research, and IAEA safeguards. The work is carried out mainly at three centres of Atomic Energy of Canada Limited--the Chalk River Nuclear Laboratories, the Whiteshell Nuclear Research Establishment, and the Sheridan Park Engineering Laboratories--and at Ontario Hydro's Research Laboratories. Canadian universities, consultants, manufacturers, and suppliers also provide expertise in their areas of specialization

Environmental Assessment of R&D Programmes

DEFF Research Database (Denmark)

Lyhne, Ivar; Byriel, Inger Pihl

2013-01-01

cause severe negative environmental impacts. This paper presents an innovative environmental assessment practice on R&D programmes in Denmark. It reports on the challenges and experiences of assessing the Danish R&D programme ForskEL, which promotes R&D projects within the electricity sector......Despite their important role in shaping the technologies of the future, public research and development (R&D) programmes are rarely based on systematic assessments of the environmental effects. R&D programmes thus allocate a huge amount of financial resources to projects, which potentially may....... The programme is characterised by uncertainty about impacts and incomparable project types and technologies. A methodology for dealing with these challenges is presented, and experiences from a testing of the methodology on the 2012 programme are reflected upon. Finally the assessment is discussed in terms...

Interferência da língua falada na escrita de crianças: processos de apagamento da oclusiva dental /d/ e da vibrante final /r/ Interference of the spoken language on children's writing: cancellation processes of the dental occlusive /d/ and final vibrant /r/

Directory of Open Access Journals (Sweden)

Socorro Cláudia Tavares de Sousa

2009-01-01

Full Text Available O presente trabalho tem como objetivo investigar a influência da língua falada na escrita de crianças em relação aos fenômenos do cancelamento da dental /d/ e da vibrante final /r/. Elaboramos e aplicamos um instrumento de pesquisa em alunos do Ensino Fundamental em escolas de Fortaleza. Para a análise dos dados obtidos, utilizamos o software SPSS. Os resultados nos revelaram que o sexo masculino e as palavras polissílabas são fatores que influenciam, de forma parcial, a realização da variável dependente /no/ e que os verbos e o nível de escolaridade são elementos condicionadores para o cancelamento da vibrante final /r/.The present study aims to investigate the influence of the spoken language in children's writing in relation to the phenomena of cancellation of dental /d/ and final vibrant /r/. We elaborated and applied a research instrument to children from primary school in Fortaleza. We used the software SPSS to analyze the data. The results showed that the male sex and the words which have three or more syllable are factors that influence, in part, the realization of the dependent variable /no/ and that verbs and level of education are conditioners elements for the cancellation of the final vibrant /r/.

4D Dynamic Required Navigation Performance Final Report

Science.gov (United States)

Finkelsztein, Daniel M.; Sturdy, James L.; Alaverdi, Omeed; Hochwarth, Joachim K.

2011-01-01

New advanced four dimensional trajectory (4DT) procedures under consideration for the Next Generation Air Transportation System (NextGen) require an aircraft to precisely navigate relative to a moving reference such as another aircraft. Examples are Self-Separation for enroute operations and Interval Management for in-trail and merging operations. The current construct of Required Navigation Performance (RNP), defined for fixed-reference-frame navigation, is not sufficiently specified to be applicable to defining performance levels of such air-to-air procedures. An extension of RNP to air-to-air navigation would enable these advanced procedures to be implemented with a specified level of performance. The objective of this research effort was to propose new 4D Dynamic RNP constructs that account for the dynamic spatial and temporal nature of Interval Management and Self-Separation, develop mathematical models of the Dynamic RNP constructs, "Required Self-Separation Performance" and "Required Interval Management Performance," and to analyze the performance characteristics of these air-to-air procedures using the newly developed models. This final report summarizes the activities led by Raytheon, in collaboration with GE Aviation and SAIC, and presents the results from this research effort to expand the RNP concept to a dynamic 4D frame of reference.

Global R&D through the Intelligent Manufacturing Systems (IMS) program

Science.gov (United States)

Huray, Paul G.

1997-01-01

The industry-led, international intelligent manufacturing systems (IMS) program provides a special vehicle for joint research and development between government, industry and academia in the United States, Canada, Japan, Australia, and Europe. Since its beginning in 1989, the IMS program has progressed through a feasibility phase which demonstrated that international legal barriers, trade issues, and intellectual property problems could be overcome. The program is constructed to provide higher quality design, customized products, shorter delivery cycles and lower costs. Interactions between partner companies have led to new business opportunities for mutual profit and some claim to have learned strategic information about their international competitors. The IMS program is growing through the participation of hundreds of corporate and university partners who share responsibilities in specific projects and jointly reap benefits for their manufacturing products and processes. The logic for choosing or not choosing the IMS mechanisms will be discussed and R and D projects will be identified.

Supersymmetrization schemes of D=4 Maxwell algebra

International Nuclear Information System (INIS)

Kamimura, Kiyoshi; Lukierski, Jerzy

2012-01-01

The Maxwell algebra, an enlargement of Poincaré algebra by Abelian tensorial generators, can be obtained in arbitrary dimension D by the suitable contraction of O(D-1,1)⊕O(D-1,2) (Lorentz algebra ⊕ AdS algebra). We recall that in D=4 the Lorentz algebra O(3,1) is described by the realification Sp R (2|C) of complex algebra Sp(2|C)≃Sl(2|C) and O(3,2)≃Sp(4). We study various D=4N-extended Maxwell superalgebras obtained by the contractions of real superalgebras OSp R (2N-k;2|C)⊕OSp(k;4) (k=0,1,2,…,2N); (extended Lorentz superalgebra ⊕ extended AdS superalgebra). If N=1 (k=0,1,2) one arrives at three different versions of simple Maxwell superalgebra. For any fixed N we get 2N different superextensions of Maxwell algebra with n-extended Poincaré superalgebras (1⩽n⩽N) and the internal symmetry sectors obtained by suitable contractions of the real algebra O R (2N-k|C)⊕O(k). Finally the comments on possible applications of Maxwell superalgebras are presented.

Firm Segmentation as a Tool for R&D Policy Evaluation: Revisiting the Taxonomy of Firms Engaged in International R&D Networks

Directory of Open Access Journals (Sweden)

Bruno Brandao Fischer

2013-05-01

Full Text Available As we have addressed in an earlier article, quantitative evaluation of R&D policies often approaches the outcomes of initiatives without effectively considering differential impacts on economic agents. Our goal is to confirm the existence of “segments” of firms according to their outcomes arising from participation in a given R&D program. Data is gathered from Eureka Program’s Final Reports (2000-2005 and 2006-2008 from Spanish, Italian, French, British, and German firms. Classification focus is directed towards variables related to innovation projects’ outcomes. Log-likelihood clustering method was used. Tests for differences between clusters in terms of some variables of interest were performed. Results are consistent with the hypothesis of marked heterogeneity in firms’ outcomes. This methodology offers a valuable instrument for RTD policymakers in terms of monitoring and ex post intervention.

R&D status of linear collider technology at KEK

Science.gov (United States)

Urakawa, Junji

1992-02-01

This paper gives an outline of the Japan Linear Collider (JLC) project, especially JLC-I. The status of the various R&D works is particularly presented for the following topics: (1) electron and positron sources, (2) S-band injector linacs, (3) damping rings, (4) high power klystrons and accelerating structures, (5) the final focus system. Finally, the status of the construction and design studies for the Accelerator Test Facility (ATF) is summarized.

The USERDA transport R and D program for environment and safety

International Nuclear Information System (INIS)

Sisler, J.A.

1976-01-01

This paper describes the U.S. Energy Research and Development Administration's (ERDA) transportation environment and safety research and development program for energy fuels and wastes, including background, current activities, and future plans. It will serve as an overview and integrating factor for the several related technical papers to be presented at this meeting which will enlarge on the detail of specific projects. The transportation R and D program provides for the environmental and safety review of transport systems and procedures; standards development; and package, vehicle, and systems testing for nuclear materials transport. A primary output of the program is the collection, processing, and dissemination of transport environment and safety data, shipment statistics, and technical information. Special transport projects which do not easily fit elsewhere in ERDA are usually done as a part of this program. (author)

Openness, Growth and R&D Spillovers : Uncovering the Missing Link?

NARCIS (Netherlands)

Lejour, (Arjan Marcel); Nahuis, Richard

2000-01-01

We examine the trade-related diffusion of R&D in three steps. First, using OECD and UNESCO data we provide an overview of global R&D expenditures. Second, we estimate the relation between sectoral R&D expenditures and growth. Finally, these R&D linkages are incorporated in WorldScan: a dynamic

Lepton accelerators and radiation sources: R and D investment at BNL

International Nuclear Information System (INIS)

Ben-Zvi, I.; Fernow, R.; Gallardo, J.; Hart, M.; Hastings, J.; Johnson, E.; Krinsky, S.; Palmer, R.; Yu, L.H.

1997-03-01

Brookhaven National Laboratory (BNL) has shown its determination to remain at the forefront of accelerator based science through its continued investment in long range accelerator R and D. The laboratory has a broad program in accelerator technology development including projects such as high T c magnets at RHIC, Siberian Snakes at the AGS, brightness upgrades on the NSLS storage ring, and spallation source R and D in several departments. This report focuses on a segment of the overall program: the lepton accelerator and coherent radiation source R and D at the laboratory. These efforts are aimed at (1) development of high brightness electron beams, (2) novel acceleration techniques, (3) seeded Free Electron Laser (FEL) development, and (4) R and D for a muon collider. To pursue these objectives, BNL ha over the past decade introduced new organizational arrangements. The BNL Center for Accelerator Physics (CAP) is an interdepartmental unit dedicated to promoting R and D which, cannot be readily conducted within the programs of operating facilities. The Accelerator Test Facility (ATF) is managed by CAP and NSLS as a user facility dedicated to accelerator and beam physics problems of interest to both the High Energy Physics and Basic Energy Sciences programs of the DOE. Capitalizing on these efforts, the Source Development Laboratory (SDL) was established by the NSLS to facilitate coordinated development of sources and experiments to produce and utilize coherent sub-picosecond synchrotron radiation. This White Paper describes the programs being pursued at CAP, ATF and SDL aimed at advancing basic knowledge of lepton accelerators and picosecond radiation sources

The Italian R and D and industrial program for an accelerator driven system experimental plant

International Nuclear Information System (INIS)

Carta, M.; Gherardi, G.; Buono, S.; Cinotti, L.

2001-01-01

Accelerator Driven Systems (ADS), coupling an accelerator with a target and a sub-critical reactor, could simultaneously burn minor actinides and transmute long-lived fission products, while producing a consistent amount of electrical energy. A team of Italian R and D organizations and industries has set up a network of coordinated programs addressed to study the design issues of an 80 MW th Experimental Facility. The present memo focalizes the attention on some results obtained by the R and D activities and by the ongoing industrial short term activities aiming at the preparation of the proposed preliminary design, leaving the deal to define the details of the subsequent medium term activities to the expected common program in the European context. (author)

An R and D program for targetry and capture at a neutrino factory and muon collider source

International Nuclear Information System (INIS)

Hassenein, A.; Bernadon, A.; Beshears, D.L.; Brown, K.A.; Cates, M.C.; Fabich, A.; Fernow, R.C.; Finfrock, C.C.; Fukui, Y.; Gabriel, T.A.; Gassner, D.M.; Green, M.A.; Greene, G.A.; Haines, J.R.; Johnson, C.D.; Kahn, S.A.; King, B.J.; Kirk, H.G.; Lettry, J.; Lu, C.; Ludewig, H.; McDonald, K.T.; Miller, J.R.; Mokhov, N.V.; Palmer, R.B.; Pendzick, A.F.; Prigl, R.; Ravn, H.; Reginato, L.L.; Riemer, B.W.; Samulyak, R.; Scaduto, J.; Simos, N.; Spampinato, P.T.; Thieberger, P.; Tsai, C.-C.; Tsang, T.Y.F.; Wang, H.; Weggel, R.J.; Zeller, A.

2003-01-01

The need for intense muon beams for muon colliders and for neutrino factories based on muon storage rings leads to a concept of 1-4 MW proton beams incident on a moving target that is inside a 20-T solenoid magnet, with a mercury jet as a preferred example. Novel technical issues for such a system include disruption of the mercury jet by the proton beam and distortion of the jet on entering the solenoid, as well as more conventional issues of materials lifetime and handling of activated materials in an intense radiation environment. As part of the R and D program of the Neutrino Factory and Muon Collider Collaboration, an R and D effort related to targetry is being performed within the context of experiment E951 at Brookhaven National Laboratory, first results of which are reported here

A comparative analysis of three of ERDA's major R and D programs

International Nuclear Information System (INIS)

Weyant, J.P.

1978-01-01

The benefits attributable to alternative energy R and D programs should be evaluated in terms of how well the technologies contribute as integral elements of the total United States energy system. Thus, the present model simulates the dynamics of the evolution of the total energy system by requiring both existing and new technologies to compete for introduction on a cost-competitive basis that considers the time phasing of (1) retirement of energy conversion facilities, (2) growth in end-use demands, and (3) escalation of the costs of extracting depleting domestic energy resources. This approach contrasts with a static model used by the Energy Research and Development Administration, wherein assumptions must be made for each future year of interest for (1) maximum capacity constraints for alternative types of conversion facilities and (2) the cost of energy resources. The present model is used to compare the relative consequences and merits of the technology products from the following three of ERDA's major energy R and D programs: (1) the liquid-metal fast breeder reactor (LMFBR), (2) synthetic fuels derived from coal and oil shale, and (3) improved efficiencies for end-use devices (e.g. space heaters). (author)

Neutrino factory and muon collider collaboration R and D activities

International Nuclear Information System (INIS)

Zisman, Michael S.; Neutrino Factory and Muon Collider Collaborat

2001-01-01

The Neutrino Factory and Muon Collider Collaboration (MC) comprises about 140 U.S. and non-U.S. accelerator and particle physicists. The MC is carrying out an R and D program aimed at validating the critical design concepts required for the construction of such machines. We are committed to encouraging international cooperation and coordination of the R and D effort. Main activities of the MC include a Targetry program, a MUCOOL program, a component development program, and a theory and simulation effort. Moreover, the MC has participated in several feasibility studies for a complete Neutrino Factory facility, with the aim of identifying any additional R and D activities needed to prepare a Zeroth-order Design Report (ZDR) in about two years and a Conceptual Design report (CDR) about two years thereafter. In this paper, the R and D goals in each area will be indicated, and the present status and future plans of the R and D program will be described

Alabama DOE/EPSCoR traineeship program. Final report, September 28, 1991--September 28, 1995

Energy Technology Data Exchange (ETDEWEB)

Pruitt, K.M.; April, G.C.

1995-12-01

This report covers programmatic accomplishments of the Alabama DOE/EPSCoR Traineeship Program for the period September 28, 1991 to September 29, 1995. The Alabama DOE/EPSCoR Traineeship Program is an integral part of this state`s efforts to address barriers that inhibit the full development and substantial growth of energy-related research at the six major research institutions and at Alabama`s Historically Black Colleges and Universities (HBCUs). To overcome these barriers it was determined that the following actions were needed: Area 1: Strengthening the Research Faculty Base Area 2: Increasing the Number of Outstanding Graduate Students Area 3: Improving the Research Environment Area 4: Developing the Human Resources Base Area 5. Improving the Energy-related Infrastructure, Collaborations and Communications. Although the DOE/EPSCoR Traineeship Grant complements each of the areas listed above, its primary emphasis is the enhancement of opportunities for graduate students. The extent to which this program has met this challenge during the three year funding period constitutes the substance of this report.

Summary of findings of the R&D committee

Energy Technology Data Exchange (ETDEWEB)

Kenley, C.R. [Lockheed Martin Idaho Technologies, Idaho Falls (United States); Kokenge, B.R. [BRK Associates Inc., Farmersville, OH (United States)

1996-05-01

In March 1995, the Department of Energy`s (DOE) Nuclear Materials Stabilization Task Group (NMST) chartered a committee to formulate a research and development (R&D) plan in response to Sub-recommendation (2) of Defense Nuclear Facilities Safety Board (DNFSB) Recommendation 94-1. The NMSTG was established as an organizational unit operating under the auspices of the DOE Office of the Environmental Management. As a result of its efforts, the Research Committee concluded that, in general, the technology needs for stabilizing 94-1 nuclear materials are being adequately met by existing or planned DOE programs. At the same time, the committee, in the form of recommendations, noted specific R&D program areas that should be addressed by the NMSTG. These recommendations are documented in the R&D plan and formulated based on: (1) existing {open_quotes}gaps{close_quotes} in DOE`s R&D stabilization program, (2) the relative maturity of various technologies, and (3) other important R&D program issues that, in the judgement of the committee, should be addressed by the NMSTG. A systems engineering approach, derived form the aerospace industry, was applied to the various stabilization technologies to assess their relative maturity and availability for use in treating 94-1 nuclear materials.

CANDU Safety R&D Status, Challenges, and Prospects in Canada

Directory of Open Access Journals (Sweden)

W. Shen

2015-01-01

Full Text Available In Canada, safe operation of CANDU (CANada Deuterium Uranium; it is a registered trademark of Atomic Energy of Canada Limited reactors is supported by a full-scope program of nuclear safety research and development (R&D in key technical areas. Key nuclear R&D programs, facilities, and expertise are maintained in order to address the unique features of the CANDU as well as generic technology areas common to CANDU and LWR (light water reactor. This paper presents an overview of the CANDU safety R&D which includes background, drivers, current status, challenges, and future directions. This overview of the Canadian nuclear safety R&D programs includes those currently conducted by the COG (CANDU Owners Group, AECL (Atomic Energy of Canada Limited, Candu Energy Inc., and the CNSC (Canadian Nuclear Safety Commission and by universities via UNENE (University Network of Excellence in Nuclear Engineering sponsorship. In particular, the nuclear safety R&D program related to the emerging CANDU ageing issues is discussed. The paper concludes by identifying directions for the future nuclear safety R&D.

The dynamics of R and D in evolution from imitation to innovation: lessons from technical cooperation program

International Nuclear Information System (INIS)

Ainul Hayati Daud; Khairul Zaman Mohd Dahlan

2002-01-01

Over the last two decades, Malaysia has implemented more than 80 R and D projects valued almost USD 20 millions, under the multilateral, bilateral and regional Technical Cooperation Program (TCP). Attempts were made to examine the dynamics of R and D of the TCP focusing on radiation processing projects using the analytical frameworks such as absorptive capacity, crisis construction, dynamic learning process and technology transfer. This paper describes the contribution of TCP towards the process of technological learning and discusses the process of building technological capability in the dynamic of R and D evolution from imitation to innovation. (Author)

The GEDEON program. An R and D initiative in support of the ADS development in France

International Nuclear Information System (INIS)

Salvatores, M.; Schapira, J.P.; Mouney, H.; Carluec, B.

1999-01-01

The GEDEON initiative: R and D on basic physics issues of ADS. Also: R and D in the perspective of a 'demo' experiment. The context in France: R and D for waste management; R and D organisations have collaboration agreements with industrial partners; the French Ministry for Research has promoted a study on the relevance of an ADS 'demo'. The context in Europe: The 5th Framework Program; A tri-country initiative towards an 'ASAP demo' (at present being enlarged to other countries). GEDEON is coordinating and supporting R and D activities in this context. Four organisations are presently supporting financially GEDEON: CEA, CNRS, EdF, FRAMATOME. Workshop help to focus on issues and to start cooperative projects nuclear data, pyrochemistry, and materials for target and window. Also: some joint projects, such as the MUSE program at MASURCA. Links with ongoing R and D activities such as High Intensity Accelerators. Present R and D fields: Spallation Target physics: double differential data (analysis of SATURNE experiments), neutron multiplicities (GANIL), spallation product distribution (GSI). Nuclear Data Np-237 and Tc-99 σ c in the resonance region (GEEL), Am-242 σ f at thermal energy (ILL). Nuclear data validation with integral experiments: MA sample irradiation and Irradiated Fuel Analysis. Spallation physics and particle transport modeling: the SPARTE code. Neutronics and control of subcritical cores: the MUSE Program at MASURCA; MUSE-1, MUSE-2 (1995-96) with Cf-252 external source, MUSE-3 with commercial 14 eV n source. Future program: MASURCA cores coupling to a performing deuteron accelerator (GENEPI). System studies: scenario studies (e.g. double strata fuel cycle); use of thorium. Also reduced radiotoxicity 'at the origin'. Potential of pyrochemistry to handle highly active fuel and supports not compatible with PUREX (heterogeneous recycling targets, dedicated MA-based fuels); also: potential of the IFR concept revisited (homogeneous recycling). Potential of

KNK I Test Program, Final Report Part 1

International Nuclear Information System (INIS)

Kathol, W.

1976-01-01

The compact sodium cooled nuclear reactor KNK I of the Karlsruhe Research Center reached full power for the first time in February 1974. The goal of KNK I is to collect experience for the construction and operation of larger reactors, such as SNR 300. In order to deepen these experiences, a test program was drawn up and conducted from 1973 until 1975 within the framework of R and D work on the development of fast breeder reactors. The program included individual tasks concerning reactor design, safety instrumentation, irradiation and post-examination as well as behavior of components during operation. The performance of the tests was essentially governed by the licensing procedure imposed under the atomic energy act for the construction and operation of nuclear facilities. This report is the first part of the final report of the test program

The operation of a Research and Development (R&D) program and its significance for practice change in community pharmacy.

Science.gov (United States)

Hermansyah, Andi; Sainsbury, Erica; Krass, Ines

2017-01-01

Community pharmacy practice in Australia is changing and Research and Development (R&D) in community pharmacy plays an important role in contributing to the changes. A range of Cognitive Pharmacy Services (CPS) were developed from R&D programs, yet their implementation has been minimal indicating slow practice change within community pharmacy. Given the vital role of R&D, little is known about the operation and the extent to which it has been effective in supporting practice change in community pharmacy. In depth, semi-structured interviews were conducted with 27 key stakeholders in the pharmacy and healthcare system in Australia. All interviews were audio-recorded, transcribed ad verbatim and analysed using an inductive approach. Participants perceived that the R&D program has played an important role in the advent of CPS. Furthermore, they considered that evidence generated by the R&D projects is a critical influence on policy formulation, funding and implementation of CPS into practice. However, policy decisions and subsequent implementation are also influenced by other factors associated with context and facilitation which in turn foster or inhibit effective Knowledge Translation (KT) in the community pharmacy sector. While R&D programs have been viewed as essential for supporting changes in community pharmacy practice through development and funding of CPS, the overall impact has been small, as contemporary practice continues to be predominantly a dispensing model. Given the complexity and dynamic nature of the community pharmacy system, stakeholders must take into account the inter-relationship between context, evidence and facilitation for successful KT in community pharmacy practice.

Post-irradiation examination and R and D programs using irradiated fuels at KAERI

International Nuclear Information System (INIS)

Chun, Yong Bum; Min, Duck Kee; Kim, Eun Ka and others

2000-12-01

This report describes the Post-Irradiation Examination(PIE) and R and D programs using irradiated fuels at KAERI. The objectives of post-irradiation examination (PIE) for the PWR irradiated fuels, CANDU fuels, HANARO fuels and test fuel materials are to verify the irradiation performance and their integrity as well as to construct a fuel performance data base. The comprehensive utilization program of the KAERI's post-irradiation examination related nuclear facilities such as Post-Irradiation Examination Facility (PIEF), Irradiated Materials Examination Facility (IMEF) and HANARO is described

Post-irradiation examination and R and D programs using irradiated fuels at KAERI

International Nuclear Information System (INIS)

Chun, Yong Bum; So, Dong Sup; Lee, Byung Doo; Lee, Song Ho; Min, Duck Kee

2001-09-01

This report describes the Post-Irradiation Examination(PIE) and R and D programs using irradiated fuels at KAERI. The objectives of post-irradiation examination (PIE) for the PWR irradiated fuels, CANDU fuels, HANARO fuels and test fuel materials are to verify the irradiation performance and their integrity as well as to construct a fuel performance data base. The comprehensive utilization program of the KAERI's post-irradiation examination related nuclear facilities such as Post-Irradiation Examination Facility (PIEF), Irradiated Materials Examination Facility (IMEF) and HANARO is described

Draft program plan for TNS: The Next Step after the Tokamak Fusion Test Reactor. Part II. R and D needs assessment

International Nuclear Information System (INIS)

Roberts, M.

1977-12-01

The information contained in this document represents the brief but intensive efforts of the Oak Ridge TNS Program Team to answer the following questions: (1) Is there an adequate basis of R and D support for the TNS program as a central, ambitious goal for the fusion program. (2) What are the principal gaps in the current and projected R and D program. (3) What must be done to permit operation of TNS in the mid 1980s. The findings of our preliminary study provide these answers to the questions: (1) The physics and technology base does exist from which to start the TNS design as a central fusion program goal. (2) We have specific recommendations for new emphasis in certain physics and technology areas to minimize R and D program gaps. (3) TNS conceptual design must be started now, and a close look at organizing the fusion program around a TNS project is an essential need to support operation in the mid 1980s

2003 RIA R AND D WORKSHOP.

Energy Technology Data Exchange (ETDEWEB)

OZAKI, S.ET AL.

2003-08-26

The 2003 RIA R&D Workshop was held on August 26-28, 2003 at the Four Points Sheraton Hotel in Bethesda, Maryland. This Workshop was chaired by Satoshi Ozaki of BNL and sponsored by the Nuclear Physics Division of DOE, with the help of Oak Ridge Institute for Science and Education (ORISE). The purpose of this workshop was to understand the present status of R&D efforts for RIA, to evaluate the needs for further R&D, and to identify opportunities for international collaborations. The workshop examined and documented the current pre-conceptual design for RIA, identifying areas where decisions on technical options remain. The status of the current RIA R&D program was documented, recognizing areas where efforts were needed in light of what had been learned. The ongoing and planned R&D activities for operating and planned rare-isotope facilities were presented, enabling the workshop to be a venue to develop coordinated R&D efforts of mutual benefit to U.S. and international efforts. The scientific program for the first day (August 26, 2003) consisted mostly of invited talks presented by major research groups involved in RIA and other RI beam facilities. The talks included those covering: Science of RIA and the RIA Facility Performance Requirements; The Reference RIA Facility Pre-CDR design that was used for the NSAC cost exercise (M. Harrison Sub-Panel) in January 2001; New or latest perspectives on the RIA design at ANL & MSU; and RI Beam facility plans and overview of the R&D activities at overseas laboratories. The second day (August 27, 2003) was devoted to contributed talks on continuing R&D, including that which had been supported by DOE RIA R&D funds. The third day (August 28, 2003) began with open panel discussions in the morning, including further input from participants. The panel members discussed the present status of the RIA planning and R&D needs in a closed session for the rest of the day, and then worked on report planning and writing. This Workshop

Value engineering and the role of R and D in the neutral beam program

International Nuclear Information System (INIS)

Fink, J.

1979-01-01

Value Engineering, simply defined, is a systematic approach to getting more for your money. It has been used to reduce the cost of a wide variety of products by the D.O.D. and in principle, should be applicable to various phases of the Neutral Beam Program. With respect to R and D, the principles of Value Engineering must be used with caution. They are most effective in evaluating directed development with very specific goals, but can be misleading when considering advanced innovative work

The R and D program on geothermal energy of the commission of the European communities results and future

International Nuclear Information System (INIS)

Louwrier, K.P.; Garnish, J.D.; Staroste, E.

1992-01-01

DGXII of the Commission of the European Communities has supported research and development in the field of the geothermal energy since 1975, and has just begun the fifth, and probably final, four year program. The first program concentrated on the data collection in order to establish the geothermal potential of the Community. This work resulted in the drafting and publication of two Atlases, one dealing with sub-surface temperatures and one with geothermal resources. Three multidisciplinary studies were undertaken on three known geothermal reservoirs with different characteristics, in order to test the validity of various exploration methods. A major element in recent years has been Hot Dry Rock studies, which have evolved during the course of the various program s from laboratory experiments and work in shallow holes towards a European test site where an international team of scientists coordinates research teams from different Member States. Basic scientific support to exploitation of geothermal energy has been given by geochemistry. The present R and D program centers on HDR research and abatement of corrosion and scaling in geothermal systems. Besides the geothermal work the program also supports studies in deep reservoir geology

Japan's Sunshine Project. Solar energy R and D program

Energy Technology Data Exchange (ETDEWEB)

NONE

1981-05-01

This paper explains the Sunshine Project and its solar energy R and D program. The solar energy is poured into the earth at 1.04 x 10{sup 17} kcal per hour, while the energy consumption of the world in 1970 is equivalent to 30 minutes of the solar energy. It is infinite compared to fossil fuel and clean, with no extreme partiality by areas. Its problem in utilization, however, is the low energy density of 1 kw/m{sup 2} and unsteady supply caused by weather conditions, which raises difficulties in matching energy demand. These demerits and low competitiveness in cost must be overcome through R and D. Under the Sunshine Project, the solar energy utilization is in progress in the areas of thermal utilization in a building, solar thermal power generation, and photovoltaic power generation. The budget was 9.6 billion yen for fiscal 1980 and 8 billion yen for fiscal 1981. Since fiscal 1980, emphasis has been placed particularly on photovoltaic power generation. The experimental production of solar cells of 500 kW/year is scheduled as a target through fiscal 1981-82. Four demonstration plants and two central distributing substations for photovoltaic power generation are planned to be built by fiscal 1985. Also to be studied are 2 solar thermal power generation plants of 1,000 kWe each and a solar thermal system for industrial process heating. (NEDO)

Buildings R&D Breakthroughs. Technologies and Products Supported by the Building Technologies Program

Energy Technology Data Exchange (ETDEWEB)

none,

2012-04-01

This report identifies and characterizes commercially available products and emerging (near-commercial) technologies that benefited from the support of the Building Technologies Program (BTP) within the U.S. Department of Energy’s Office of Energy Efficiency and Renewable Energy. The investigation specifically focused on technology-oriented research and development (R&D) projects sponsored by BTP’s Emerging Technologies subprogram from 2005-2009.

R&D Personnel Career Routes: An Exploratory Study

OpenAIRE

Barbara Bigliardi; Alberto Ivo Dormio

2009-01-01

This study, aiming at investigate the alternative modes of career development for personnel belonging to R&D staff, addresses the extent to which career anchors are applicable to R&D staff and to examine the relationship among career anchors, gender and age, with the final purpose to add elements of discussion to the long-lasting debate about this matter. With this purpose in mind, we developed a questionnaire survey among 309 R&D personnel employed at firms belonging to the food machinery in...

D1/D5 systems in N=4 string theories

International Nuclear Information System (INIS)

Gava, Edi; Hammou, Amine B.; Morales, Jose F.; Narain, Kumar S.

2001-01-01

We propose CFT descriptions of the D1/D5 system in a class of freely acting Z 2 orbifolds/orientifolds of type IIB theory, with sixteen unbroken supercharges. The CFTs describing D1/D5 systems involve N=(4,4) or N=(4,0) sigma models on (R 3 xS 1 xT 4 x(T 4 ) N /S N )/Z 2 , where the action of Z 2 is diagonal and its precise nature depends on the model. We also discuss D1(D5)-brane states carrying non-trivial Kaluza-Klein charges, which correspond to excitations of two-dimensional CFTs of the type (R 3 xS 1 xT 4 ) N /S N xZ 2 N . The resulting multiplicities for two-charge bound states are shown to agree with the predictions of U-duality. We raise a puzzle concerning the multiplicities of three-charge systems, which is generically present in all vacuum configurations with sixteen unbroken supercharges studied so far, including the more familiar type IIB on K3 case: the constraints put on BPS counting formulae by U-duality are apparently in contradiction with any CFT interpretation. We argue that the presence of RR backgrounds appearing in the symmetric product CFT may provide a resolution of this puzzle. Finally, we show that the whole tower of D-instanton corrections to certain 'BPS saturated couplings' in the low energy effective actions match with the corresponding one-loop threshold corrections on the dual fundamental string side

Photonic network R and D activities in Japan

Science.gov (United States)

Kitayama, Ken-ichi; Miki, Tetsuya; Morioka, Toshio; Tsushima, Hideaki; Koga, Masafumi; Mori, Kazuyuki; Araki, Soichiro; Sato, Ken-ichi; Onaka, Hiroshi; Namiki, Shu; Aovama, Tomonori

2005-11-01

R and D activities on photonic networks in Japan are presented. First, milestones in current, ongoing R and D programs supported by Japanese government agencies are introduced, including long-distance and WDM fiber transmission, wavelength routing, optical burst switching, and control plane technology for IP backbone networks. Their goal was set to evolve a legacy telecommunications network to IP over WDM networks by introducing technologies for WDM and wavelength routing. We then discuss the perspectives of so-called PHASE II R and D programs for photonic networks over the next five years until 2010, by focusing on the report which has been recently issued by the Photonic Internet Forum (PIF), a consortium that has major carriers, telecom vendors, and Japanese academics as members. The PHASE II R and D programs should serve to establish a photonic platform to provide abundant bandwidth on demand, at any time on a real-time basis through the customer's initiative, to promote bandwidth-rich applications, such as grid computing, real-time digital-cinema streaming, medical and educational applications, and network storage in e-commerce.

R&D Personnel Career Routes: An Exploratory Study

Directory of Open Access Journals (Sweden)

Barbara Bigliardi

2009-05-01

Full Text Available This study, aiming at investigate the alternative modes of career development for personnel belonging to R&D staff, addresses the extent to which career anchors are applicable to R&D staff and to examine the relationship among career anchors, gender and age, with the final purpose to add elements of discussion to the long-lasting debate about this matter. With this purpose in mind, we developed a questionnaire survey among 309 R&D personnel employed at firms belonging to the food machinery industry in a Northern Italy district. The results obtained from the statistical analysis indicate that the R&D personnel’s career orientations is a predictor of their career routes preferences, confirming three possible career routes in R&D labs that were highlighted in previous studies.

High energy physics program at Texas A&M University. Final report, April 1, 1990--March 31, 1991

Energy Technology Data Exchange (ETDEWEB)

1992-12-01

The Texas A&M experimental high energy physics program has been supported since its inception by DOE Contract DE-AS05-81ER40039. During that period we established a viable experimental program at a university which before this time had no program in high energy physics. In 1990, the experimental program was augmented with a program in particle theory. In the accompanying final report, we outline the research work accomplished during the final year of this contract and the program being proposed for consideration by the Department of Energy for future grant support. Some of the particular areas covered are: Collider detector at Fermilab program; the TAMU MACRO program; SSC R&D program; SSC experimental program; and theoretical physics program.

Summary of findings of the R ampersand D committee

International Nuclear Information System (INIS)

Kenley, C.R.; Kokenge, B.R.

1996-01-01

In March 1995, the Department of Energy's (DOE) Nuclear Materials Stabilization Task Group (NMST) chartered a committee to formulate a research and development (R ampersand D) plan in response to Sub-recommendation (2) of Defense Nuclear Facilities Safety Board (DNFSB) Recommendation 94-1. The NMSTG was established as an organizational unit operating under the auspices of the DOE Office of the Environmental Management. As a result of its efforts, the Research Committee concluded that, in general, the technology needs for stabilizing 94-1 nuclear materials are being adequately met by existing or planned DOE programs. At the same time, the committee, in the form of recommendations, noted specific R ampersand D program areas that should be addressed by the NMSTG. These recommendations are documented in the R ampersand D plan and formulated based on: (1) existing open-quotes gapsclose quotes in DOE's R ampersand D stabilization program, (2) the relative maturity of various technologies, and (3) other important R ampersand D program issues that, in the judgement of the committee, should be addressed by the NMSTG. A systems engineering approach, derived form the aerospace industry, was applied to the various stabilization technologies to assess their relative maturity and availability for use in treating 94-1 nuclear materials

Expression of programmed cell death protein 4 (PDCD4) and miR-21 in urothelial carcinoma

Energy Technology Data Exchange (ETDEWEB)

Fischer, Nicolas, E-mail: simplissimus@gmx.de [Department of Urology, University of Bonn, Sigmund-Freud-Strasse 25, 53127 Bonn (Germany); Goeke, Friederike, E-mail: Friederike.goeke@ukb.uni-bonn.de [Department of Pathology, University of Bonn, Sigmund-Freud-Strasse 25, 53127 Bonn (Germany); Splittstoesser, Vera, E-mail: Veri.sp@web.de [Department of Urology, University of Bonn, Sigmund-Freud-Strasse 25, 53127 Bonn (Germany); Lankat-Buttgereit, Brigitte, E-mail: Lankatbu@staff.uni-marburg.de [Department of Internal Medicine, Philipps-University of Marburg, Baldingerstrasse, 35043 Marburg (Germany); Mueller, Stefan C., E-mail: Stefan.mueller@ukb.uni-bonn.de [Department of Urology, University of Bonn, Sigmund-Freud-Strasse 25, 53127 Bonn (Germany); Ellinger, Joerg, E-mail: Joerg.ellinger@ukb.uni-bonn.de [Department of Urology, University of Bonn, Sigmund-Freud-Strasse 25, 53127 Bonn (Germany)

2012-01-06

Highlights: Black-Right-Pointing-Pointer The tumor suppressor gene PDCD4 is down-regulated in many tumorous entities. Black-Right-Pointing-Pointer We investigate the impact of PDCD4 and its regulating factor miR-21 in urothelial carcinoma. Black-Right-Pointing-Pointer We confirm PDCD4 as a tumor suppressor gene and it could be a diagnostic marker for this tumor. -- Abstract: Background: We investigated the role of the programmed cell death 4 (PDCD4) tumor suppressor gene in specimens of transitional cell carcinoma and of healthy individuals. Methods: PDCD4 immunohistochemical expression was investigated in 294 cases in histologically proven transitional cell carcinoma in different tumorous stages (28 controls, 122 non-muscle invasive urothelial carcinoma, stages Tis-T1, 119 invasive transitional cell carcinoma stages T2-T4 and 25 metastases). MiR-21 expression, an important PDCD4 regulator, was assessed with real-time PCR analysis and showed inverse correlation to tissue PDCD4 expression. Results: Nuclear and cytoplasmatic PDCD4 immunostaining decreased significantly with histopathological progression of the tumor (p < 0001). Controls showed strong nuclear and cytoplasmatic immunohistochemical staining. MiR-21 up regulation in tissue corresponded to PDCD4 suppression. Conclusions: These data support a decisive role for PDCD4 down regulation in transitional cell carcinoma and confirm miR-21 as a negative regulator for PDCD4. Additionally, PDCD4 immunohistochemical staining turns out to be a possible diagnostic marker for transitional cell carcinoma.

Expression of programmed cell death protein 4 (PDCD4) and miR-21 in urothelial carcinoma

International Nuclear Information System (INIS)

Fischer, Nicolas; Göke, Friederike; Splittstößer, Vera; Lankat-Buttgereit, Brigitte; Müller, Stefan C.; Ellinger, Jörg

2012-01-01

Highlights: ► The tumor suppressor gene PDCD4 is down-regulated in many tumorous entities. ► We investigate the impact of PDCD4 and its regulating factor miR-21 in urothelial carcinoma. ► We confirm PDCD4 as a tumor suppressor gene and it could be a diagnostic marker for this tumor. -- Abstract: Background: We investigated the role of the programmed cell death 4 (PDCD4) tumor suppressor gene in specimens of transitional cell carcinoma and of healthy individuals. Methods: PDCD4 immunohistochemical expression was investigated in 294 cases in histologically proven transitional cell carcinoma in different tumorous stages (28 controls, 122 non-muscle invasive urothelial carcinoma, stages Tis-T1, 119 invasive transitional cell carcinoma stages T2–T4 and 25 metastases). MiR-21 expression, an important PDCD4 regulator, was assessed with real-time PCR analysis and showed inverse correlation to tissue PDCD4 expression. Results: Nuclear and cytoplasmatic PDCD4 immunostaining decreased significantly with histopathological progression of the tumor (p < 0001). Controls showed strong nuclear and cytoplasmatic immunohistochemical staining. MiR-21 up regulation in tissue corresponded to PDCD4 suppression. Conclusions: These data support a decisive role for PDCD4 down regulation in transitional cell carcinoma and confirm miR-21 as a negative regulator for PDCD4. Additionally, PDCD4 immunohistochemical staining turns out to be a possible diagnostic marker for transitional cell carcinoma.

2003 RIA R AND D WORKSHOP

International Nuclear Information System (INIS)

OZAKI, S.

2003-01-01

The 2003 RIA R and D Workshop was held on August 26-28, 2003 at the Four Points Sheraton Hotel in Bethesda, Maryland. This Workshop was chaired by Satoshi Ozaki of BNL and sponsored by the Nuclear Physics Division of DOE, with the help of Oak Ridge Institute for Science and Education (ORISE). The purpose of this workshop was to understand the present status of R and D efforts for RIA, to evaluate the needs for further R and D, and to identify opportunities for international collaborations. The workshop examined and documented the current pre-conceptual design for RIA, identifying areas where decisions on technical options remain. The status of the current RIA R and D program was documented, recognizing areas where efforts were needed in light of what had been learned. The ongoing and planned R and D activities for operating and planned rare-isotope facilities were presented, enabling the workshop to be a venue to develop coordinated R and D efforts of mutual benefit to U.S. and international efforts. The scientific program for the first day (August 26, 2003) consisted mostly of invited talks presented by major research groups involved in RIA and other RI beam facilities. The talks included those covering: Science of RIA and the RIA Facility Performance Requirements; The Reference RIA Facility Pre-CDR design that was used for the NSAC cost exercise (M. Harrison Sub-Panel) in January 2001; New or latest perspectives on the RIA design at ANL and MSU; and RI Beam facility plans and overview of the R and D activities at overseas laboratories. The second day (August 27, 2003) was devoted to contributed talks on continuing R and D, including that which had been supported by DOE RIA R and D funds. The third day (August 28, 2003) began with open panel discussions in the morning, including further input from participants. The panel members discussed the present status of the RIA planning and R and D needs in a closed session for the rest of the day, and then worked on report

R and D Developments. Research Programs on Irradiation Embrittlement of Reactor Vessel Steels

International Nuclear Information System (INIS)

Gomez Briceno, D.; Lapena, J.; Serrano, M.; Perosanz, F.

2000-01-01

Irradiation embrittlement of pressure vessel steels is a degradation mechanism time dependent that can lead to operational restrictions with adverse effects in the efficiency and life of a plant. For the last year, several research programs have been devoted to study thye evaluation of neutronic radiation effect on mechanical properties of pressure vessel steels. However, at the present, there is a growing interest on the development of new methodologies to optimize the surveillance program information, and the understanding of the irradiation damage mechanism. This paper give an overview of international research programs, and on the R+D activities carried out by the Structural Materials Project on irradiation embrittlement on pressure vessel steels. (Author)

JESS-D-16-00247 R4.pdf | forthcoming | jess | Volumes | public ...

Indian Academy of Sciences (India)

Home; public; Volumes; jess; forthcoming; JESS-D-16-00247 R4.pdf. 404! error. The page your are looking for can not be found! Please check the link or use the navigation bar at the top. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. 29th Mid-year meeting. Posted on 19 January 2018. The 29th Mid-year ...

JESS-D-16-00510 R4.pdf | forthcoming | jess | Volumes | public ...

Indian Academy of Sciences (India)

Home; public; Volumes; jess; forthcoming; JESS-D-16-00510 R4.pdf. 404! error. The page your are looking for can not be found! Please check the link or use the navigation bar at the top. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. 29th Mid-year meeting. Posted on 19 January 2018. The 29th Mid-year ...

JESS-D-16-00096 R4.pdf | forthcoming | jess | Volumes | public ...

Indian Academy of Sciences (India)

Home; public; Volumes; jess; forthcoming; JESS-D-16-00096 R4.pdf. 404! error. The page your are looking for can not be found! Please check the link or use the navigation bar at the top. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. 29th Mid-year meeting. Posted on 19 January 2018. The 29th Mid-year ...

Bridging the Gap Between Innovation and ELSA: The TA Program in the Dutch Nano-R&D Program NanoNed

NARCIS (Netherlands)

Rip, Arie; van Lente, H

2013-01-01

The Technology Assessment (TA) Program established in 2003 as part of the Dutch R&D consortium NanoNed is interesting for what it did, but also as an indication that there are changes in how new science and technology are pursued: the nanotechnologists felt it necessary to spend part of their

Cinema 4D R13 Cookbook

CERN Document Server

Szabo, Michael

2012-01-01

This book contains short recipes designed to effectively teach tools in the minimum amount of time. Each recipe hits on a topic that can be combined or incorporated with other recipes to give you the building blocks you need to start making great designs with Cinema 4D. Rather than demonstrating how to make a few specific and extensive projects, the recipes create a solid base of knowledge to help the reader understand the tools available to foster their own creativity. This book is for anyone who wants to quickly get up to speed with Cinema 4D to create 3D projects that run laps around simple

75 FR 14069 - Amendment of Using Agency for Restricted Areas R-3005A, R-3305B, R-3005C, R-3005D and R-3005E...

Science.gov (United States)

2010-03-24

...; Airspace Docket No. 10-ASO-19] RIN 2120-AA66 Amendment of Using Agency for Restricted Areas R-3005A, R-3305B, R-3005C, R-3005D and R-3005E; Fort Stewart, GA AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action changes the using agency of restricted areas R- 3005A, R-3005B...

R and D Toward a Neutrino Factory and Muon Collider

International Nuclear Information System (INIS)

Zisman, Michael S.

2011-01-01

Significant progress has been made in recent years in R and D towards a neutrino factory and muon collider. The U.S. Muon Accelerator Program (MAP) has been formed recently to expedite the R and D efforts. This paper will review the U.S. MAP R and D programs for a neutrino factory and muon collider. Muon ionization cooling research is the key element of the program. The first muon ionization cooling demonstration experiment, MICE (Muon Ionization Cooling Experiment), is under construction now at RAL (Rutherford Appleton Laboratory) in the UK. The current status of MICE will be described.

Buildings R&D Breakthroughs: Technologies and Products Supported by the Building Technologies Program

Energy Technology Data Exchange (ETDEWEB)

Weakley, Steven A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

2012-04-01

The purpose of the project described in this report is to identify and characterize commercially available products and emerging (near-commercial) technologies that benefited from the support of the Building Technologies Program (BTP) within the U.S. Department of Energy’s Office of Energy Efficiency and Renewable Energy. The investigation specifically focused on technology-oriented research and development (R&D) projects funded by BTP’s Emerging Technologies subprogram from 2005-2011.

Advanced Object-Oriented Programming in R

DEFF Research Database (Denmark)

Mailund, Thomas

2017-01-01

Learn how to write object-oriented programs in R and how to construct classes and class hierarchies in the three object-oriented systems available in R. This book gives an introduction to object-oriented programming in the R programming language and shows you how to use and apply R in an object......-oriented manner. You will then be able to use this powerful programming style in your own statistical programming projects to write flexible and extendable software. After reading Advanced Object-Oriented Programming in R, you'll come away with a practical project that you can reuse in your own analytics coding...... of data being manipulated. You will: Define and use classes and generic functions using R Work with the R class hierarchies Benefit from implementation reuse Handle operator overloading Apply the S4 and R6 classes...

Advanced Object-Oriented Programming in R

DEFF Research Database (Denmark)

Mailund, Thomas

Learn how to write object-oriented programs in R and how to construct classes and class hierarchies in the three object-oriented systems available in R. This book gives an introduction to object-oriented programming in the R programming language and shows you how to use and apply R in an object......-oriented manner. You will then be able to use this powerful programming style in your own statistical programming projects to write flexible and extendable software. After reading Advanced Object-Oriented Programming in R, you'll come away with a practical project that you can reuse in your own analytics coding...... of data being manipulated. You will: Define and use classes and generic functions using R Work with the R class hierarchies Benefit from implementation reuse Handle operator overloading Apply the S4 and R6 classes...

Fluoride removal from double four-membered ring (D4R) units in As-synthesized Ge-containing zeolites

KAUST Repository

Liu, Xiaolong

2011-11-22

Fluoride anions can be removed from the framework of as-prepared Ge-containing zeolites ITQ-13 and ITQ-17 without modification of the crystallinity and crystal habit. By contrast to all-silica ITQ-13 for which fluoride could not get out from D4R units, F is completely removed from Ge rich zeolites, even from D4R cages. This has been explained by the relaxing effect of germanium, making F less necessary for the stabilization of the small D4R units. Si/Ge ratios are similar in as-prepared and treated zeolites, indicating that the framework composition is not affected by the removal of anions. The fluoride-free zeolites possess XRD patterns similar to those of the as-made solids but their 29Si NMR spectra are significantly different, revealing the sensitivity of the method to the environment of silicon atoms in the framework. The extent of fluoride that can be removed from D4R units depends not only on the framework Ge content but also on the zeolite topology: for similar contents, F is much more easily eliminated from ITQ-17 than from ITQ-13. © 2011 American Chemical Society.

Effective Control Rights in Vertical R&D Collaboration

DEFF Research Database (Denmark)

Kloyer, Martin

2011-01-01

by allocating the so-called control rights to the supplier. These rights primarily regulate the assignment of the intellectual property rights, the control of the R&D process, and the marketing of the final products that are based on the delivered R&D results. To date, we do not have any empirical evidence......Because of increasing technological complexity of new products, the manufacturers of final products more often seek access to external sources of knowledge at the early, market-distant stages of innovation processes. However, they are confronted with a specifically high danger of moral hazard....... Traditional management instruments fail to control that danger mainly for two reasons. First, the supplier activities are not transparent. Second, market-distant R&D results are credence goods whose quality cannot be evaluated, not even ex post. It is the theory of incomplete contracts that solves the problem...

R and D directions for the development of CANDU reactors

International Nuclear Information System (INIS)

Torgerson, D.F.

1998-01-01

Full text: AECL is carrying out a comprehensive R and D programme to advance all aspects of CANDU reactor technology. These programs are focusing on three main strategic directions: improved economics, enhanced safety, and fuel cycle flexibility. R and D areas include fuel cycle development, heavy water technology, fuel channel development, safety technology, control and instrumentation, reactor chemistry, systems and components, and health and environment. In each case, the R and D programs have short, medium, and long-term goals to achieve the overall strategic directions. Most of the programs seek to further develop and exploit some of the unique characteristics of pressurized heavy water reactors. Examples of this include high neutron economy and on-power fueling which allow several different fuel cycles, the presence of large water heat sinks for enhanced safety, and modular components that can be easily replaced for plant life extension. This presentation reviews AECL's product development directions and the R and D programs that have been begun for their development

The forgotten R and D budget

International Nuclear Information System (INIS)

Hunt, R.; Mohsberg, J.

1992-01-01

The research and development budget for hydropower has dwindled in recent years. Increased R and D funding could improve hydropower's effectiveness. Of the $1.5 trillion US budget for 1992, only $1 million was devoted to research and development (R and D) for hydroelectric generation. This is because hydropower has been branded a mature technology no longer in need of R and D. Nevertheless, as the source of nearly 10 percent of all US electricity, hydropower offers the nation's best opportunity for significant increased renewable energy production in the near future. The US Department of Energy (DOE) has estimated an additional 50,000 MW of hydropower capacity is potentially developable. Of the total $3 billion R and D budget for all DOE programs in 1992, the combined R and D amount for the other primary renewable energy resources was $161.3 million. Whether mature or not, all methods of producing electricity have attendant problems and development needs that must be addressed with sufficient R and D if the US is to remain energy independent, competitive and safe as a nation. In comparing R and D budget trends for electrical generating resources during the past 10 years there are several questions to be asked: Are other mature technologies, such as coal and nuclear power, receiving budget treatment similar to hydropower? What is the intended use of the R and D funds for these mature technologies? Is any technology - medical, communications, electrical generating or other - ever so mature as to be unable to benefit from R and D? What use could the hydropower industry make of additional R and D funding? What is the commitment of the administration and Congress to developing renewable energy resources when the source of 85 percent of current renewable energy receives only $1 million for R and D of the $3 billion DOE R and D budget? This article addresses these questions

High field accelerator magnet R&D in Europe

CERN Document Server

Devred, Arnaud; Bottura, L; Chorowski, M; Fabbricatore, P; Leroy, D; den Ouden, A; Rifflet, J M; Rossi, L; Vincent-Viry, O; Volpini, G

2004-01-01

The LHC magnet R&D program has shown that the limit of NbTi technology at 1.9 K was in the 10-to-10.5-T range. Hence, to go beyond the 10-T threshold, it is necessary to change the superconducting material. Given the state of the art in HTS, the only serious candidate is Nb$_{3}$Sn. A series of dipole magnet models built at Twente University and LBNL as well as a vigorous program carried out at Fermilab have demonstrated the feasibility of Nb$_{3}$Sn magnet technology. The next step is to bring this technology to maturity, which require further conductor and conductor insulation development and a simplification of manufacturing processes. After a brief history, we review ongoing R&D programs in Europe and we present the Next European Dipole (NED) initiative promoted by the European Steering Group on Accelerator R&D (ESGARD).

The Oil Security Metrics Model: A Tool for Evaluating the Prospective Oil Security Benefits of DOE's Energy Efficiency and Renewable Energy R&D Programs

Energy Technology Data Exchange (ETDEWEB)

Greene, David L [ORNL; Leiby, Paul Newsome [ORNL

2006-05-01

Energy technology R&D is a cornerstone of U.S. energy policy. Understanding the potential for energy technology R&D to solve the nation's energy problems is critical to formulating a successful R&D program. In light of this, the U.S. Congress requested the National Research Council (NRC) to undertake both retrospective and prospective assessments of the Department of Energy's (DOE's) Energy Efficiency and Fossil Energy Research programs (NRC, 2001; NRC, 2005). ("The Congress continued to express its interest in R&D benefits assessment by providing funds for the NRC to build on the retrospective methodology to develop a methodology for assessing prospective benefits." NRC, 2005, p. ES-2) In 2004, the NRC Committee on Prospective Benefits of DOE's Energy Efficiency and Fossil Energy R&D Programs published a report recommending a new framework and principles for prospective benefits assessment. The Committee explicitly deferred the issue of estimating security benefits to future work. Recognizing the need for a rigorous framework for assessing the energy security benefits of its R&D programs, the DOE's Office of Energy Efficiency and Renewable Energy (EERE) developed a framework and approach for defining energy security metrics for R&D programs to use in gauging the energy security benefits of their programs (Lee, 2005). This report describes methods for estimating the prospective oil security benefits of EERE's R&D programs that are consistent with the methodologies of the NRC (2005) Committee and that build on Lee's (2005) framework. Its objective is to define and implement a method that makes use of the NRC's typology of prospective benefits and methodological framework, satisfies the NRC's criteria for prospective benefits evaluation, and permits measurement of that portion of the prospective energy security benefits of EERE's R&D portfolio related to oil. While the Oil Security Metrics (OSM) methodology described

Energy R and D in Germany

Energy Technology Data Exchange (ETDEWEB)

Runci, PJ

1999-11-01

Germany's total national (i.e., combined public and private sector) funding for R&D stood at $42 billion in 1997. The private sector accounted for nearly 62% ($24 billion) of the total, while the public sector accounted for approximately 38%. Since the late 1970s, when the public and private sectors each funded roughly half of Germany's R&D, the private sector has steadily assumed a larger and larger role as the dominant supporter of R&D activity, while overall government funding has remained essentially flat for much of the past two decades. In addition to declining relative to private R&D expenditures, public R&D expenditures in Germany declined by 4% in real terms between 1991 and 1997, to approximately $15 billion. The reduction in R&D investments in the public sector can be attributed in large part to the financial challenges associated with German reunification and related shifts in social priorities including efforts to address high unemployment and to rebuild basic infrastructure in the eastern states. R&D expenditures have also declined as a percentage of the total public budget, from a peak of 3.4% in 1985 to 2.7% in 1996. Energy R&D has been the hardest hit of all major socioeconomic areas of R&D expenditure funded by the German government. Between 1981 and 1997, public energy R&D fell from approximately $1.6 billion to $400 million--a 75% real decline. The $850 million reduction in Germany's fission R&D budget (which constituted two-thirds of government R&D investment in 1985) explains some 90% of the funding decline. Negative public perceptions regarding the safety and environmental impacts of nuclear energy have reduced nuclear power's viability as a long-term energy option for Germany. Discussions of a complete nuclear phaseout are now under way. At the same time, the German government has slashed its investments in fossil energy R&D by more than 90%. While energy efficiency and renewable energy technologies have fared relatively well in comparison

Financial Development, Econmic Growth and R&D Cyclical Movement

OpenAIRE

Fung, Ka Wai Terence; Lau, Chi Keung Marco

2013-01-01

This paper builds up an endogenous growth model à la Aghion and Howitt (1992) and Boucekkine et al (2005). We assume that R&D firms use only investment good as input, instead of final good as hypothesized in the above two models. We show that investment price will be a negative function of aggregate quality index; and thus decline over time. In this model, subsidy on R&D has growth-enhancing effect. Moreover, this model predicts unambiguously that R&D is procyclical.

Experiments during flow boiling of a R22 drop-in: R422D adiabatic pressure gradients

International Nuclear Information System (INIS)

Rosato, A.; Mauro, A.W.; Mastrullo, R.; Vanoli, G.P.

2009-01-01

R22, the HCFC most widely used in refrigeration and air-conditioning systems in the last years, is phasing-out. R422D, a zero ozone-depleting mixture of R125, R134a and R600a (65.1%/31.5%/3.4% by weight, respectively), has been recently proposed as a drop-in substitute. For energy consumption calculations and temperature control, it is of primary importance to estimate operating conditions after substitution. To determine pressure drop in the evaporator and piping line to the compressor, in this paper the experimental adiabatic pressure gradients during flow boiling of R422D are reported for a circular smooth horizontal tube (3.00 mm inner radius) in a range of operating conditions of interest for dry-expansion evaporators. The data are used to establish the best predictive method for calculations and its accuracy: the Moreno-Quiben and Thome method provided the best predictions for the whole database and also for the segregated data in the annular flow regime. Finally, the experimental data have been compared with the adiabatic pressure gradients of both R22 and its much used alternative R407C available in the literature.

Recent Korean R&D in Satellite Communications

Science.gov (United States)

Lee, Ho-Jin; Kim, Jae Moung; Lee, Byung-Seub; Lee, Han; Ryoo, Jang-Soo

The R&D in satellite communications in Korea has been driven mainly by KCC (Korea Communications Commission) but in a small scale compared to Korea space development program organized by MEST (Ministry of Education, Science and Technology). Public and civilian satcom sector R&D has been led mainly by ETRI with small/medium companies contrary to rare investment in private sector while military sector R&D has been orchestrated by ADD with defense industry. By the COMS (Communication, Ocean and Meteorological Satellite) experimental Ka-band payload, Korea pursues a space qualification of own technology for national infrastructure evolution as well as industrialization of space R&D results. Once COMS launched and space qualified in 2009, subsequent application experiments and new technology R&D like UHDTV will entail service and industry promotion. The payload technology is expected for the next Korean commercial satellites or for new OBP satellites. The COMS ground control system and GNSS ground station technologies are under development for COMS operation and enhanced GNSS services along with advent of Galileo respectively. Satellite broadband mobile VSAT based on DVB-S2/RCS (+M) and low profile tracking antennas have been developed for trains, ships, and planes. While APSI is developing GMR-1 based Thuraya handset functions, ETRI is designing IMT-Advanced satellite radio interface for satellite and terrestrial dual-mode handheld communication system like Japanese STICS, with universities' satellite OFDM researches. A 21GHz Ka-band higher-availability scalable HD broadcasting technology and SkyLife's hybrid satellite IPTV technology are being developed. In near term Korea will extend R&D programs to upgrade the space communication infrastructure for universal access to digital opportunity and safer daily life from disaster, and to promote space green IT industrialization, national security, and space resources sovereign. Japanese stakeholders are invited to establish

JAERI R & D on accelerator-based transmutation under OMEGA program

Energy Technology Data Exchange (ETDEWEB)

Takizuka, T.; Nishida, T.; Mizumoto, M. [Japan Atomic Energy Research Institute, Ibaraki-ken (Japan)] [and others

1995-10-01

The overview of the Japanese long-term research and development program on nuclide partitioning and transmutation, called {open_quotes}OMEGA,{close_quotes} is presented. Under this national program, major R&D activities are being carried out at JAERI, PNC, and CRIEPI. Accelerator-based transmutation study at JAERI is focused on a dedicated transmutor with a subcritical actinide-fueled subcritical core coupled with a spallation target driven by a high intensity proton accelerator. Two types of system concept, solid system and molten-salt system, are discussed. The solid system consists of sodium-cooled tungsten target and metallic actinide fuel. The molten-salt system is fueled with molten actinide chloride that acts also as a target material. The proposed plant transmutes about 250 kg of minor actinide per year, and generates enough electricity to power its own accelerator. JAERI is proposing the development of an intense proton linear accelerator ETA with 1.5 GeV-10 mA beam for engineering tests of accelerator-based transmutation. Recent achievements in the accelerator development are described.

Final report for the 'Melt-Vessel Interactions' Project. European Union R and TD Program 4th Framework. MVI project final research report

International Nuclear Information System (INIS)

Sehgal, B.R.; Dinh, T.N.; Nourgaliev, R.R.; Bui, V.A.; Green, J.; Kolb, G.; Karbojian, A.; Theerthan, S.A.; Gubaidulline, A.; Bonnet, J.M.; Rouge, S.; Narcoux, M.; Liegeois, A.; Turland, B.D.; Dobson, G.P.; Siccama, A.; Ikonen, K.; Parozzi, F.; Kolev, N.; Caira, M.

1999-04-01

The Melt Vessel Interaction (MVI) project is concerned with the consequences of the interactions that a core melt, generated during a postulated severe accident in a light water reactor, may have with the pressure vessel. In particular, the issues concerned with the failure of the vessel bottom head are the focus of the research. The specific objectives of the project are to obtain data and develop validated models, which could be applied to prototypic plants, and accident conditions, for resolution of issues related to the melt vessel interactions. The project work has been performed by nine partners having varied responsibility. The work included a large number of experiments, with simulant materials, whose observations and results are employed, respectively, to understand the physical mechanisms and to develop validated models. Applications to the prototypic geometry and conditions have also been performed. This report is volume 1 of the Final Report for the Project, in which a summary of the progress achieved in the experimental program is provided. We have, however, included some aspects of the modeling activities. Volume 2 of the Final report describes the progress achieved in the modeling program. The progress achieved in the experimental and modeling parts of the Project has led to the resolution of some of the issues of melt vessel interaction. Considerable progress was also achieved towards resolution of the remaining issues

A Goal Programming R&D (Research and Development) Project Funding Model of the U.S. Army Strategic Defense Command Using the Analytic Hierarchy Process.

Science.gov (United States)

1987-09-01

A187 899 A GOAL PROGRANNIN R&D (RESEARCH AND DEVELOPMENT) 1/2 PROJECT FUNDING MODEL 0 (U) NAVAL POSTGRADUATE SCHOOL MONTEREY CA S M ANDERSON SEP 87...PROGRAMMING R&D PROJECT FUNDING MODEL OF THE U.S. ARMY STRATEGIC DEFENSE COMMAND USING THE ANALYTIC HIERARCHY PROCESS by Steven M. Anderson September 1987...jACCESSION NO TITI E (Influde Securt ClauAIcatsrn) A Goal Programming R&D Project Funding Model of the U.S. Army Strategic Defense Command Using the

II meeting of R and D in radioactive waste management

International Nuclear Information System (INIS)

Astudillo Pastor, J.

1995-01-01

The report includes the principal features on the content and development of the Second Seminar on R+D in the Management of Radioactive Waste organised by ENRESA, the National Company responsible for waste management in Spain. More than 200 scientists working in the Second R+D Program have participated. The topical areas included low-intermediate level and high-level wastes as well as Radiation Protection and Decommissioning and Dismantling issues. During the Seminar two round tables and the official presentation of the Third R+D Program have been included. (Author)

High Field Magnet R and D in the USA

International Nuclear Information System (INIS)

Gourlay, S.A.

2003-01-01

Accelerator magnet technology is currently dominated by the use of NbTi superconductor. New and more demanding applications for superconducting accelerator magnets require the use of alternative materials. Several programs in the US are taking advantage of recent improvements in Nb 3 Sn to develop high field magnets for new applications. Highlights and challenges of the US R and D program are presented along with the status of conductor development. In addition, a new R and D focus, the US LHC Accelerator Research Program, will be discussed.

High Field Magnet R and D in the USA

International Nuclear Information System (INIS)

Gourlay, Stephen A.

2003-01-01

Accelerator magnet technology is currently dominated by the use of NbTi superconductor. New and more demanding applications for superconducting accelerator magnets require the use of alternative materials. Several programs in the US are taking advantage of recent improvements in Nb 3 Sn to develop high field magnets for new applications. Highlights and challenges of the US R and D program are presented along with the status of conductor development. In addition, a new R and D focus, the US LHC Accelerator Research Program, will be discussed

Draft report: a selection methodology for LWR safety R and D programs and proposals

International Nuclear Information System (INIS)

Husseiny, A.A.; Ritzman, R.L.

1980-03-01

The results of work done to develop a methodology for selecting LWR safety R and D programs and proposals is described. A critical survey of relevant decision analysis methods is provided including the specifics of multiattribute utility theory. This latter method forms the basis of the developed selection methodology. Details of the methodology and its use are provided along with a sample illustration of its application

Draft report: a selection methodology for LWR safety R and D programs and proposals

Energy Technology Data Exchange (ETDEWEB)

Husseiny, A. A.; Ritzman, R. L.

1980-03-01

The results of work done to develop a methodology for selecting LWR safety R and D programs and proposals is described. A critical survey of relevant decision analysis methods is provided including the specifics of multiattribute utility theory. This latter method forms the basis of the developed selection methodology. Details of the methodology and its use are provided along with a sample illustration of its application.

Impact of the Polymorphism Near MC4R (rs17782313 on Obesity- and Metabolic-Related Traits in Women Participating in an Aerobic Training Program

Directory of Open Access Journals (Sweden)

Leońska-Duniec Agata

2017-08-01

Full Text Available The C/T polymorphism (rs17782313 mapped 188 kb downstream of the melanocortin-4 receptor gene (MC4R shows a strong relationship with an increased body mass index (BMI and the risk of type 2 diabetes. However, the information on polymorphism’s potential modifying effect on obesity- and metabolic-related traits achieved through training is still unknown. Therefore, we decided to check if selected body measurements observed in physically active participants would be modulated by the genotype. The genotype distribution was examined in a group of 201 Polish women measured for chosen traits before and after the completion of a 12 week moderate-intensive aerobic training program. A statistically significant relationship between the glucose level and the genotype was identified (p = 0.046. Participants with CC and CT genotypes had a higher glucose level during the entire study period compared with the TT genotype. However, our results did not confirm the relationship between the C allele and an increased BMI or other obesity-related traits. Additionally, we did not observe a near MC4R C/T polymorphism x physical activity interaction. However, our results revealed that majority of obesity-related variables changed significantly during the 12 week training program. The effect sizes (d of these changes ranged from small to medium (d = 0.11-0.80, whereas the largest effect (d = 0.80; i.e. medium was reported for the fat mass content (FM. We found a relationship between the near MC4R C/T polymorphism and an increased glucose level, and it is thus a candidate to influence type 2 diabetes. Interestingly, after the 12 week training program, participants with the C (risk allele with fasting hyperglycemia had a normal glucose level. Although, this change was not statistically significant, it shows an important trend which needs further investigation.

FY2013 Energy Storage R&D Progress Report

Energy Technology Data Exchange (ETDEWEB)

none,

2014-02-01

The FY 2013 Progress Report for Energy Storage R&D focuses on advancing the development of batteries to enable a large market penetration of hybrid and electric vehicles. Program targets focus on overcoming technical barriers to enable market success including: (1) significantly reducing battery cost, (2) increasing battery performance (power, energy, durability), (3) reducing battery weight & volume, and (4) increasing battery tolerance to abusive conditions such as short circuit, overcharge, and crush.

AECL'S (Atomic Energy Canada Limited) R and D program in health and environmental sciences

International Nuclear Information System (INIS)

Osborne, R.V.

1996-01-01

Radiological protection is a fundamental requirement in any nuclear technology endeavour. It is also an area where public concerns are often expressed. If protection is inadequate, or is believed to be so, or if concerns are not addressed, the beneficial application of nuclear technologies is inhibited. Historically. AECL, as the driver of nuclear technology in Canada, has ensured that the growing Canadian nuclear industry and other users of the technology have a sound technical base to support, explain and confirm all aspects of radiological protection. Meeting this need has meant developing and maintaining R%D programs in environmental sciences, health physics, radiation biology, and radiological health matters in general. The programs undertaken encompass the links from sources of radiation exposure and radionuclides to potential impact on biota and on human health. The behaviours of radionuclides released to the atmosphere, surface waters, or ground waters are examined and described quantitatively to enable predictions to be made of the radiation doses received in different parts of the biosphere and by people. Radiation properties and human physiological and biokinetic processes are studied to provide quantitative links from exposure to radiation dose in tissues and organs. Biological processes involved in determining whether there are any consequences to health from small absorbed doses are identified at levels ranging from molecular level, to cells in tissue culture, and animals. Throughout the programs, required measurement technologies are developed. The results of the R%D have contributed to radiological protection programs being soundly based and, equally important, are being seen to be soundly based. (author)

Recruiting Program for the Future R and D Leader in Nuclear Science and Technology

International Nuclear Information System (INIS)

Song, Keechan; Im, Ohsoo; Cho, Changyun; Min, Hwanki; Lee, Jungkong; Jung, Sunghyun; Kim, Jungbae; Joo, Hoyoung

2013-05-01

Nuclear technology export, which is represented by a nuclear research reactor, Gen-IV nuclear system development and nuclear safety research are the current key issues in the nuclear field. In order to achieve these missions in the nuclear industry, nuclear HRD(human resource development). However, recruiting of young scientists and researchers in the nuclear field has not been sufficient for last 10 years. Moreover, many experienced persons have been retired during this period. Under these circumstances, the structure of the nuclear experts wind up with vary distorted one. As one of comprehensive countermeasures, the recruiting program for the future R and D leaders come to issues. The human network to lead future R and Ds in the nuclear science and technology is set up, and this network is persistantly maintained and expanded to recruit potential leaders in the nuclear R and D and industry. As one of these strategy and plans for recruiting competent young scientists, who are studying in the U. S., the 2 times briefing meeting were held, and human networking and expertise DB for more than 300 participants were established

R&D Incentives for Neglected Diseases

Science.gov (United States)

Dimitri, Nicola

2012-01-01

Neglected diseases are typically characterized as those for which adequate drug treatment is lacking, and the potential return on effort in research and development (R&D), to produce new therapies, is too small for companies to invest significant resources in the field. In recent years various incentives schemes to stimulate R&D by pharmaceutical firms have been considered. Broadly speaking, these can be classified either as ‘push’ or ‘pull’ programs. Hybrid options, that include push and pull incentives, have also become increasingly popular. Supporters and critics of these various incentive schemes have argued in favor of their relative merits and limitations, although the view that no mechanism is a perfect fit for all situations appears to be widely held. For this reason, the debate on the advantages and disadvantages of different approaches has been important for policy decisions, but is dispersed in a variety of sources. With this in mind, the aim of this paper is to contribute to the understanding of the economic determinants behind R&D investments for neglected diseases by comparing the relative strength of different incentive schemes within a simple economic model, based on the assumption of profit maximizing firms. The analysis suggests that co-funded push programs are generally more efficient than pure pull programs. However, by setting appropriate intermediate goals hybrid incentive schemes could further improve efficiency. PMID:23284648

R&D incentives for neglected diseases.

Directory of Open Access Journals (Sweden)

Nicola Dimitri

Full Text Available Neglected diseases are typically characterized as those for which adequate drug treatment is lacking, and the potential return on effort in research and development (R&D, to produce new therapies, is too small for companies to invest significant resources in the field. In recent years various incentives schemes to stimulate R&D by pharmaceutical firms have been considered. Broadly speaking, these can be classified either as 'push' or 'pull' programs. Hybrid options, that include push and pull incentives, have also become increasingly popular. Supporters and critics of these various incentive schemes have argued in favor of their relative merits and limitations, although the view that no mechanism is a perfect fit for all situations appears to be widely held. For this reason, the debate on the advantages and disadvantages of different approaches has been important for policy decisions, but is dispersed in a variety of sources. With this in mind, the aim of this paper is to contribute to the understanding of the economic determinants behind R&D investments for neglected diseases by comparing the relative strength of different incentive schemes within a simple economic model, based on the assumption of profit maximizing firms. The analysis suggests that co-funded push programs are generally more efficient than pure pull programs. However, by setting appropriate intermediate goals hybrid incentive schemes could further improve efficiency.

R&D incentives for neglected diseases.

Science.gov (United States)

Dimitri, Nicola

2012-01-01

Neglected diseases are typically characterized as those for which adequate drug treatment is lacking, and the potential return on effort in research and development (R&D), to produce new therapies, is too small for companies to invest significant resources in the field. In recent years various incentives schemes to stimulate R&D by pharmaceutical firms have been considered. Broadly speaking, these can be classified either as 'push' or 'pull' programs. Hybrid options, that include push and pull incentives, have also become increasingly popular. Supporters and critics of these various incentive schemes have argued in favor of their relative merits and limitations, although the view that no mechanism is a perfect fit for all situations appears to be widely held. For this reason, the debate on the advantages and disadvantages of different approaches has been important for policy decisions, but is dispersed in a variety of sources. With this in mind, the aim of this paper is to contribute to the understanding of the economic determinants behind R&D investments for neglected diseases by comparing the relative strength of different incentive schemes within a simple economic model, based on the assumption of profit maximizing firms. The analysis suggests that co-funded push programs are generally more efficient than pure pull programs. However, by setting appropriate intermediate goals hybrid incentive schemes could further improve efficiency.

[Overexpression of miR-519d-3p inhibits the proliferation of DU-145 prostate cancer cells by reducing TRAF4].

Science.gov (United States)

Li, Xiaohui; Han, Xingtao; Yang, Jinhui; Sun, Jiantao; Wei, Pengtao

2018-01-01

Objective To observe the effect of microRNA-519d-3p (miR-519d-3p) on the proliferation of prostate cancer cells and explore the possible molecular mechanism. Methods The expression level of miR-519d-3p in PC-3, DU-145, 22RV1, PC-3M, LNCaP human prostate cancer cells and RWPE-1 human normal prostate epithelial cells was detected by real-time quantitative PCR. miR-519d-3p mimics or negative control microRNAs (miR-NC) was transfected into the prostate cancer cells with the lowest level of miR-519d-3p expression. Transfection efficiency was examined. The effect of miR-519d-3p on the cell cycle of prostate cancer was detected by flow cytometry. MTT assay and plate clone formation assay were used to detect its effect on the proliferation of prostate cancer cells. Bioinformatics software was used to predict and dual luciferase reporter assay was used to validate the target gene of miR-519d-3p. Real-time quantitative PCR was used to detect the expression of miR-519d-3p target gene. Western blot analysis was used to detect the expression of target gene protein and downstream protein. Results The expression of miR-519d-3p in normal prostate epithelial cells was significantly higher than that in prostate cancer cells, and the lowest was found in DU-145 cells. After transfected with miR-519d-3p mimics, the expression level of miR-519d-3p in DU-145 cells increased significantly. Bioinformatics prediction and dual luciferase reporter gene confirmed that tumor necrosis factor receptor associated factor 4 (TRAF4) was the target gene of miR-519d-3p. Overexpression of miR-519d-3p significantly reduced the expression of TRAF4 gene and its downstream TGF-β signaling pathway proteins in the prostate cancer cells. Conclusion The expression of miR-519d-3p is down-regulated in prostate cancer cells. Overexpression of miR-519d-3p can inhibit the proliferation of prostate cancer cells. The possible mechanism is that miR-519d-3p inhibits the expression of TRAF4.

R&D cooperation versus R&D subcontracting: empirical evidence from French survey data.

OpenAIRE

Estelle Dhont-Peltrault; Etienne Pfister

2007-01-01

This paper uses a survey of French firms active in R&D to identify the determinants of R&D outsourcing and of the ensuing trade-off between R&D subcontracting and R&D cooperation. Internal R&D expenditures increase both the probability of outsourcing and the number of R&D partners. Investment in fundamental R&D, group belonging, and the sector’s high R&D intensity positively influences the probability of R&D outsourcing but have less impact on the number of partners. R&D subcontracting is mor...

Exact ∇{sup 4}R{sup 4} couplings and helicity supertraces

Energy Technology Data Exchange (ETDEWEB)

Bossard, Guillaume [Centre de Physique Théorique, Ecole Polytechnique, Université Paris-Saclay,91128 Palaiseau Cedex (France); Pioline, Boris [Laboratoire de Physique Théorique et Hautes Energies, CNRS UMR 7589,Université Pierre et Marie Curie,4 place Jussieu, 75252 Paris cedex 05 (France); CERN, Theoretical Physics Department,1211 Geneva 23 (Switzerland)

2017-01-12

In type II string theory compactified on a d-dimensional torus T{sup d} down to D=10−d dimensions, the R{sup 4} and ∇{sup 4}R{sup 4} four-graviton couplings are known exactly, for all values of the moduli, in terms of certain Eisenstein series of the U-duality group E{sub d}(ℤ). In the limit where one circle in the torus becomes large, these couplings are expected to reduce to their counterpart in dimension D+1, plus threshold effects and exponentially suppressed corrections corresponding to BPS black holes in dimension D+1 whose worldline winds around the circle. By combining the weak coupling and large radius limits, we determine these exponentially suppressed corrections exactly, and demonstrate that the contributions of 1/4-BPS black holes to the ∇{sup 4}R{sup 4} coupling are proportional to the appropriate helicity supertrace. Mathematically, our results provide the complete Fourier expansion of the next-to-minimal theta series of E{sub d+1}(ℤ) with respect to the maximal parabolic subgroup with Levi component E{sub d} for d≤6, and the complete Abelian part of the Fourier expansion of the same for d=7.

Risk taking and effective R&D management.

Science.gov (United States)

Banholzer, William F; Vosejpka, Laura J

2011-01-01

Several key strategies can be used to manage the risk associated with innovation to create maximum value. These include balancing the timing of investments versus cash flows, management of fads, prioritization across the company, savvy portfolio management, and a system of metrics that measure real success. Successful R&D managers will do whatever is necessary to manage the risks associated with an R&D program and stick to their long-term strategy.

Final Report

Energy Technology Data Exchange (ETDEWEB)

Webb, Robert C. [Texas A& M University; Kamon, Teruki [Texas A& M University; Toback, David [Texas A& M University; Safonov, Alexei [Texas A& M University; Dutta, Bhaskar [Texas A& M University; Dimitri, Nanopoulos [Texas A& M University; Pope, Christopher [Texas A& M University; White, James [Texas A& M University

2013-11-18

Overview The High Energy Physics Group at Texas A&M University is submitting this final report for our grant number DE-FG02-95ER40917. This grant has supported our wide range of research activities for over a decade. The reports contained here summarize the latest work done by our research team. Task A (Collider Physics Program): CMS & CDF Profs. T. Kamon, A. Safonov, and D. Toback co-lead the Texas A&M (TAMU) collider program focusing on CDF and CMS experiments. Task D: Particle Physics Theory Our particle physics theory task is the combined effort of Profs. B. Dutta, D. Nanopoulos, and C. Pope. Task E (Underground Physics): LUX & NEXT Profs. R. Webb and J. White(deceased) lead the Xenon-based underground research program consisting of two main thrusts: the first, participation in the LUX two-phase xenon dark matter search experiment and the second, detector R&D primarily aimed at developing future detectors for underground physics (e.g. NEXT and LZ).

R and D on co-working transport schemes in Geant4

Energy Technology Data Exchange (ETDEWEB)

Pia, M G; Saracco, P; Sudhakar, M [INFN Sezione di Genova, Via Dodecaneso 33, 16146 Genova (Italy); Zoglauer, A [University of California at Berkeley, Berkeley, CA 94720-7450 (United States); Augelli, M [CNES, 18 Av. Edouard Belin, 31401 Toulouse (France); Gargioni, E [University Medical Center Hamburg-Eppendorf, D-20246 Hamburg (Germany); Kim, C H [Hanyang University, 17 Haengdang-dong, Seongdong-gu, Seoul, 133-791 (Korea, Republic of); Quintieri, L [INFN Laboratori Nazionali di Frascati, Via Enrico Fermi 40, I-00044 Frascati (Italy); Filho, P P de Queiroz; Santos, D de Souza [IRD, Av. Salvador Allende, s/n. 22780-160, Rio de Janeiro, RJ (Brazil); Weidenspointner, G [MPI Halbleiterlabor, Otto-Hahn-Ring 6, D-81739 Muenchen (Germany); Begalli, M, E-mail: mariagrazia.pia@ge.infn.i [UERJ, R. Sao Francisco Xavier, 524. 20550-013, Rio de Janeiro, RJ (Brazil)

2010-04-01

A research and development (R and D) project related to the extension of the Geant4 toolkit has been recently launched to address fundamental methods in radiation transport simulation. The project focuses on simulation at different scales in the same experimental environment; this problem requires new methods across the current boundaries of condensed-random-walk and discrete transport schemes. The new developments have been motivated by experimental requirements in various domains, including nanodosimetry, astronomy and detector developments for high energy physics applications.

The Importance of International Cooperation for German R and D on Radwaste Management

International Nuclear Information System (INIS)

Steininger, W.

2006-01-01

Participation in international R and D projects and programs is of great importance for German R and D institutions. This is underlined by a lot of past and present R and D activities. These activities are embedded in the non-site specific research work funded by the Ministry of Economics and Technology (BMWi) which is the responsible ministry. The paper will focus on this R and D work. The paper addresses briefly the present status of the nuclear waste management policy in Germany, the responsibilities, and objectives of R and D related to High-Level Waste (HLW) disposal. International collaboration in projects conducted in foreign underground research laboratories (URL) and disposal programs as well as activities within the 6. Framework Program of the European Commission (EC) are described. (authors)

R&D Nuggets

Science.gov (United States)

RSS Archive Videos XML DOE R&D Accomplishments DOE R&D Accomplishments searchQuery × Find searchQuery x Find DOE R&D Acccomplishments Navigation dropdown arrow The Basics dropdown arrow Home About &D Nuggets Database dropdown arrow Search Tag Cloud Browse Reports Database Help Finding Aids

Energy R and D in Germany; TOPICAL

International Nuclear Information System (INIS)

PJ Runci

1999-01-01

Germany's total national (i.e., combined public and private sector) funding for R and D stood at$42 billion in 1997. The private sector accounted for nearly 62% ($24 billion) of the total, while the public sector accounted for approximately 38%. Since the late 1970s, when the public and private sectors each funded roughly half of Germany's R and D, the private sector has steadily assumed a larger and larger role as the dominant supporter of R and D activity, while overall government funding has remained essentially flat for much of the past two decades. In addition to declining relative to private R and D expenditures, public R and D expenditures in Germany declined by 4% in real terms between 1991 and 1997, to approximately$15 billion. The reduction in R and D investments in the public sector can be attributed in large part to the financial challenges associated with German reunification and related shifts in social priorities including efforts to address high unemployment and to rebuild basic infrastructure in the eastern states. R and D expenditures have also declined as a percentage of the total public budget, from a peak of 3.4% in 1985 to 2.7% in 1996. Energy R and D has been the hardest hit of all major socioeconomic areas of R and D expenditure funded by the German government. Between 1981 and 1997, public energy R and D fell from approximately$1.6 billion to$400 million--a 75% real decline. The$850 million reduction in Germany's fission R and D budget (which constituted two-thirds of government R and D investment in 1985) explains some 90% of the funding decline. Negative public perceptions regarding the safety and environmental impacts of nuclear energy have reduced nuclear power's viability as a long-term energy option for Germany. Discussions of a complete nuclear phaseout are now under way. At the same time, the German government has slashed its investments in fossil energy R and D by more than 90%. While energy efficiency and renewable energy

Outsourcing R&D

DEFF Research Database (Denmark)

Hsuan, Juliana; Mahnke, Volker

2011-01-01

Outsourcing R&D is an increasingly explored corporate practice. Extant research advanced our initial understanding of its increasing importance and benefits. While the associated literature has blossomed, the enthusiasm of R&D managers is tenured by an increasing realization of the possible......&D, suggest a simple, yet integrative model on the relation between outsourcing R&D and performance, and offer a research agenda that is instrumental in guiding companies’ process-management and design strategies when seeking to benefit from the outsourcing of R&D....

FY2016 Advanced Batteries R&D Annual Progress Report

Energy Technology Data Exchange (ETDEWEB)

None, None

2017-08-31

The Advanced Batteries research and development (R&D) subprogram within the DOE Vehicle Technologies Office (VTO) provides support and guidance for projects focusing on batteries for plug-in electric vehicles. Program targets focus on overcoming technical barriers to enable market success including: (1) significantly reducing battery cost, (2) increasing battery performance (power, energy, durability), (3) reducing battery weight & volume, and (4) increasing battery tolerance to abusive conditions such as short circuit, overcharge, and crush. This report describes the progress made on the research and development projects funded by the Battery subprogram in 2016. This section covers the Vehicle Technologies Office overview; the Battery subprogram R&D overview; Advanced Battery Development project summaries; and Battery Testing, Analysis, and Design project summaries. It also includes the cover and table of contents.

Effectiveness of public support for R&D and entrepreneurship

NARCIS (Netherlands)

Mohnen, P.

2017-01-01

The papers by Dortet-Bernadet and Sicsic and by Redor in this issue examine respectively the success of R&D financial support programs in stimulating private R&D and the success of subsidized start-ups for the unemployed in creating long-lasting firms. Both papers focus on small French firms. Both

Metallurgical Bonding Development of V-4Cr-4Ti Alloy for the DIII-D Radiative Divertor Program

International Nuclear Information System (INIS)

Smith, J.P.; Johnson, W.R.; Trester, P.W.

1998-01-01

General Atomics (GA), in conjunction with the Department of Energy's (DOE) DIII-D Program, is carrying out a plan to utilize a vanadium alloy in the DIII-D tokamak as part of the DIII-D Radiative Divertor (RD) upgrade. The V-4Cr-4Ti alloy has been selected in the U.S. as the leading candidate vanadium alloy for fusion applications. This alloy will be used for the divertor fabrication. Manufacturing development with the V-4Cr-4Ti alloy is a focus of the DIII-D RD Program. The RD structure, part of which will be fabricated from V-4Cr-4Ti alloy, will require many product forms and types of metal/metal bonded joints. Metallurgical bonding methods development on this vanadium alloy is therefore a key area of study by GA. Several solid state (non-fusion weld) and fusion weld joining methods are being investigated. To date, GA has been successful in producing ductile, high strength, vacuum leak tight joints by all of the methods under investigation. The solid state joining was accomplished in air, i.e., without the need for a vacuum or inert gas environment to prevent interstitial impurity contamination of the V-4Cr-4Ti alloy

ITER central solenoid manufacturing R and D

International Nuclear Information System (INIS)

Jay Jayakumar, R.; Tsuji, H.; Ohsaki, O.

2001-01-01

The International Thermonuclear Experimental Reactor (ITER) Engineering Design Activity (EDA) includes the development of high performance superconductors, high current joints between superconducting cables and insulating materials. Also in the EDA, the resulting products of this R and D are incorporated in a Central Solenoid Model Coil which utilizes full size conductors. The manufacturing of the model coil and components has led to the development of the design, materials, tooling and process which are fully applicable to the manufacture of the ITER relevant CS coil. The R and D is essentially complete and final stages of the CS Model Coil manufacturing are underway. (author)

ITER central solenoid manufacturing R and D

International Nuclear Information System (INIS)

Jayakumar, R.J.; Tsuji, H.; Ohsaki, O.

1999-01-01

The International Thermonuclear Experimental Reactor (ITER) Engineering Design Activity (EDA) includes the development of high performance superconductors, high current joints between superconducting cables and insulating materials. Also in the EDA, the resulting products of this R and D are incorporated in a Central Solenoid Model Coil which utilizes full size conductors. The manufacturing of the model coil and components has led to the development of the design, materials, tooling and process which are fully applicable to the manufacture of the ITER relevant CS coil. The R and D is essentially complete and final stages of the CS Model Coil manufacturing are underway. (author)

Final Remedial Investigation Report Area of Contamination (AOC) 57. Volume II. Appendices A through D

Science.gov (United States)

2000-06-01

2 TPHC SPLT SAMPLE RESULTS 1996 FmD PROGRAM FORT DEVENS, MAssACHUSETrS Fl~w SAMPLE OPF-SrrE ON-SrrE ISEAI EF 573106 TPHC 18300 1000 57* 2 EF573006...U ; r r ýC co .. ~ ~ 4 OO 00 ftA -tt ~ 1j ’CJ~ . V Var V AL v vv vv v v vv vv 000 0000 C𔃺 ’ 0000 - a00 a00 coC’ 00U1 00 N (D Q.0 0.0. 0.0 D . 0.0 0

The INFN-FBK pixel R&D program for HL-LHC

Science.gov (United States)

Meschini, M.; Dalla Betta, G. F.; Boscardin, M.; Calderini, G.; Darbo, G.; Giacomini, G.; Messineo, A.; Ronchin, S.

2016-09-01

We report on the ATLAS and CMS joint research activity, which is aiming at the development of new, thin silicon pixel detectors for the Large Hadron Collider Phase-2 detector upgrades. This R&D is performed under special agreement between Istituto Nazionale di Fisica Nucleare and FBK foundation (Trento, Italy). New generations of 3D and planar pixel sensors with active edges are being developed in the R&D project, and will be fabricated at FBK. A first planar pixel batch, which was produced by the end of year 2014, will be described in this paper. First clean room measurement results on planar sensors obtained before and after neutron irradiation will be presented.

The INFN-FBK pixel R&D program for HL-LHC

International Nuclear Information System (INIS)

Meschini, M.; Dalla Betta, G.F.; Boscardin, M.; Calderini, G.; Darbo, G.; Giacomini, G.; Messineo, A.; Ronchin, S.

2016-01-01

We report on the ATLAS and CMS joint research activity, which is aiming at the development of new, thin silicon pixel detectors for the Large Hadron Collider Phase-2 detector upgrades. This R&D is performed under special agreement between Istituto Nazionale di Fisica Nucleare and FBK foundation (Trento, Italy). New generations of 3D and planar pixel sensors with active edges are being developed in the R&D project, and will be fabricated at FBK. A first planar pixel batch, which was produced by the end of year 2014, will be described in this paper. First clean room measurement results on planar sensors obtained before and after neutron irradiation will be presented.

Subsidizing R&D cooperatives

NARCIS (Netherlands)

Hinloopen, J.

2001-01-01

A framework is developed with which the implementation of two commonly used R&D-stimulating policies can be evaluated: providing R&D subsidies and sustaining the formation of R&D cooperatives. Subsidized R&D cooperatives can also be analyzed. The analysis shows that providing R&D subsidies is more

A note on duplication of R&D and R&D subsidies

OpenAIRE

Sami Dakhlia; Akram Temimi; Flavio Menezes

2004-01-01

We show that the presumed incompatibility of uncoordinated R&D and competition is not fundamental, but hinges on the nature of R&D spillovers. As a consequence, R&D subsidies may be more effective than previously thought.

Dynamics, integrability and topology for some classes of Kolmogorov Hamiltonian systems in R+4

Science.gov (United States)

Llibre, Jaume; Xiao, Dongmei

2017-02-01

In this paper we first give the sufficient and necessary conditions in order that two classes of polynomial Kolmogorov systems in R+4 are Hamiltonian systems. Then we study the integrability of these Hamiltonian systems in the Liouville sense. Finally, we investigate the global dynamics of the completely integrable Lotka-Volterra Hamiltonian systems in R+4. As an application of the invariant subsets of these systems, we obtain topological classifications of the 3-submanifolds in R+4 defined by the hypersurfaces axy + bzw + cx2 y + dxy2 + ez2 w + fzw2 = h, where a , b , c , d , e , f , w and h are real constants.

China’s R&D for Energy Efficient Buildings: Insights for U.S. Cooperation with China

Energy Technology Data Exchange (ETDEWEB)

Yu, Sha; Evans, Meredydd

2010-04-01

This report includes an evaluation of China’s current activities and future direction in building energy efficiency R&D and its relevance to DOE’s R&D activities under the Building Technologies Program in the Office of Energy Efficiency and Renewable Energy. The researchers reviewed the major R&D programs in China including the so-called 973 Program, the 863 Program, and the Key Technology R&D Program1 as well as the research activities of major research institutes. The report also reviewed several relevant documents of the Chinese government, websites (including the International Energy Agency and national and local governments in China), newsletters, and financial information listed in the program documents and websites.

Mapping R&D within Multinational Networks: Evidence from the Electronics Industry

Science.gov (United States)

Urze, Paula; Manatos, Maria João

Based on the final results of the R&D.COM - Local R&D COMpetencies within Global Value Chains project, this paper aims at mapping the trajectories of delocalised R&D units within a multinational’s global strategy and designing the knowledge flows within the global value chain. This analysis was performed using typologies proposed in the theoretical framework, which help us to have an overview of the network. The methodology is grounded on one extended case study that involves a local R&D unit (Portugal), a foreign R&D unit (Netherlands) and the headquarters (Norway) - developed on a multinational from the electronics industry. This case is an example of a multinational company where R&D is developed mainly in the headquarters but it is also delocalised to some subsidiaries with a certain level of autonomy.

FY2015 Energy Storage R&D Annual Progress Report

Energy Technology Data Exchange (ETDEWEB)

None, None

2016-04-30

The Energy Storage research and development (R&D) subprogram within the DOE Vehicle Technologies Office (VTO) provides support and guidance for projects focusing on batteries for plug-in electric vehicles. Program targets focus on overcoming technical barriers to enable market success including: (1) significantly reducing battery cost, (2) increasing battery performance (power, energy, durability), (3) reducing battery weight & volume, and (4) increasing battery tolerance to abusive conditions such as short circuit, overcharge, and crush.

On backstops and boomerangs. Environmental R and D under technological uncertainty

International Nuclear Information System (INIS)

Goeschl, Timo; Perino, Grischa

2009-01-01

In areas such as climate change, the recent economic literature has been emphasizing and addressing the pervasive presence of uncertainty. This paper considers a new and salient form of uncertainty, namely uncertainty regarding the environmental characteristics of 'green' innovations. Here, R and D may generate both backstop technologies and technologies that turn out to involve a new pollution problem ('boomerangs'). In the optimum, R and D will therefore typically be undertaken more than once. Extending results from multi-stage optimal control theory, we present a tractable model with a full characterization of the optimal pollution and R and D policies and the role of uncertainty. In this setting, (i) the optimal R and D program is defined by a research trigger condition in which the decision-maker's belief about the probability of finding a backstop enters in an intuitive way; (2) a decreasing probability of finding a backstop leads to the toleration of higher pollution levels, slower R and D, a slower turnover of technologies, and an ambiguous effect on the expected number of innovations; (3) learning about the probability of a backstop is driven by failures only and leads to decreasing research incentives; and (4) small to moderate delays in the resolution of technological uncertainty do not affect the optimal policy. (author)

Persistence of monopoly, innovation, and R&D spillovers

Czech Academy of Sciences Publication Activity Database

Kováč, E.; Žigić, Krešimir

2016-01-01

Roč. 70, č. 4 (2016), s. 714-734 ISSN 1090-9443 R&D Projects: GA ČR GA15-24642S Institutional support: RVO:67985998 Keywords : dynamic duopoly * R&D spillovers * persistence of monopoly Subject RIV: AH - Economics

Energy R and D in the Netherlands

Energy Technology Data Exchange (ETDEWEB)

EEM Luiten; JJ Dooley; K Blok

1999-09-07

This report documents trends in R and D and in particular (public) energy R and D in the Netherlands. Besides quantitative information on R and D and energy R and D, the report gives an impression of changes in science and technology policy, energy policy and changes in energy research priorities (both organizational and financial). In the Netherlands, 2.09% of GDP (or $6.7 billion) was invested in R and D activities in 1995. The private sector financed 46% of all R and D in that year. A small but significant fraction (9.3%) of the research performed in the Netherlands is financed by foreign public and private sector entities. Energy R and D has been identified by the national Strategic Foresight Activity as an important area of R and D for government support in the future. This is due in part to the overall decline in public support for energy R and D that occurred from 1985 to 1995. However, recent concern over climate change and energy policy has resulted in increased budgets for energy R and D. Recent policy documents (e.g., the Memorandum on Energy R and D in April 1998) and initiatives (e.g., a recent university energy R and D program; intensification of climate policy, partly in R and D) indicate the growing interest in addressing the issue of climate change partly through energy R and D. The Dutch government believes that the liberalization of the energy market in the Netherlands justifies an active role for the government to guarantee the longer-term transformation to a sustainable energy system. In terms of climate policy, the expanded and more efficient use of natural gas is seen as a suitable transition option towards a sustainable energy system. However, energy efficiency (and in particular energy efficiency in the industrial sector) and the introduction of renewable technologies (solar energy, wind energy and biomass) are generally favored for the long term. Recently, additional funding was allocated for research on industrial &apos

A closer look at the R{sub D} and R{sub D{sup ∗}} anomalies

Energy Technology Data Exchange (ETDEWEB)

Bardhan, Debjyoti [Department of Theoretical Physics, Tata Institute of Fundamental Research, 1 Homi Bhabha Road, Mumbai 400005 (India); Byakti, Pritibhajan [Department of Theoretical Physics, Indian Association for the Cultivation of Science,2A & 2B, Raja S.C. Mullick Road, Jadavpur, Kolkata 700 032 (India); Ghosh, Diptimoy [Department of Particle Physics and Astrophysics, Weizmann Institute of Science, Rehovot 76100 (Israel)

2017-01-27

The measurement of R{sub D} (R{sub D{sup ∗}}), the ratio of the branching fraction of B̄→Dτν̄{sub τ}(B̄→D{sup ∗}τν̄{sub τ}) to that of B̄→Dlν̄{sub l}(B̄→D{sup ∗}lν̄{sub l}), shows 1.9σ(3.3σ) deviation from its Standard Model (SM) prediction. The combined deviation is at the level of 4σ according to the Heavy Flavour Averaging Group (HFAG). In this paper, we perform an effective field theory analysis (at the dimension 6 level) of these potential New Physics (NP) signals assuming SU(3){sub C}×SU(2){sub L}×U(1){sub Y} gauge invariance. We first show that, in general, R{sub D} and R{sub D{sup ∗}} are theoretically independent observables and hence, their theoretical predictions are not correlated. We identify the operators that can explain the experimental measurements of R{sub D} and R{sub D{sup ∗}} individually and also together. Motivated by the recent measurement of the τ polarisation in B̄→D{sup ∗}τν̄{sub τ} decay, P{sub τ}(D{sup ∗}) by the Belle collaboration, we study the impact of a more precise measurement of P{sub τ}(D{sup ∗}) (and a measurement of P{sub τ}(D)) on the various possible NP explanations. Furthermore, we show that the measurement of R{sub D{sup ∗}} in bins of q{sup 2}, the square of the invariant mass of the lepton-neutrino system, along with the information on τ polarisation and the forward-backward asymmetry of the τ lepton, can completely distinguish the various operator structures. We also provide the full expressions of the double differential decay widths for the individual τ helicities in the presence of all the 10 dimension-6 operators that can contribute to these decays.

FAA perspectives on historical wake turbulence R&D to recent operational implementations

Science.gov (United States)

2017-06-03

A major intent of this presentation is to delineate why the many years of wake turbulence R&D are finally yielding beneficial operational implementations. It will highlight lessons learned from past R&D and going forward for NextGen and beyond.

French reprocessing and waste management R and D

International Nuclear Information System (INIS)

Lefevre, J.; Baudin, G.; Viala, M.

1991-01-01

The R and D facilities, briefly described here, are very large in France, covering α, β and γ research on the laboratory, prototype and pilot plant scales. Thanks to these resources, many innovations have been designed for UP3, concerning the overall process: shearing, dissolution, clarification, offgas treatment, extraction cycles, acid recovery, aqueous and organic effluent treatment, in-line conditioning of process wastes and fission products, process control and analysis. The effort has not stopped with the startup of UP3. A new R and D unit, Atalante, at Marcoule, will start operating in late 1991. Innovative R and D programs have been set up to prepare for the future

Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells

DEFF Research Database (Denmark)

Frankel, Lisa; Christoffersen, Nanna R; Jacobsen, Anders

2008-01-01

growth. Using array expression analysis of MCF-7 cells depleted of miR-21, we have identified mRNA targets of mir-21 and have shown a link between miR-21 and the p53 tumor suppressor protein. We furthermore found that the tumor suppressor protein Programmed Cell Death 4 (PDCD4) is regulated by miR-21......MicroRNAs are emerging as important regulators of cancer-related processes. The miR-21 microRNA is overexpressed in a wide variety of cancers and has been causally linked to cellular proliferation, apoptosis, and migration. Inhibition of mir-21 in MCF-7 breast cancer cells causes reduced cell...... and demonstrated that PDCD4 is a functionally important target for miR-21 in breast cancer cells....

An R&D Management Framework for Eco-Technology

Directory of Open Access Journals (Sweden)

Kenji Sano

2011-08-01

Full Text Available Although research and development (R&D affects new value-added creation, including that related to environmental aspects, there is little literature dealing with the integration of R&D management and eco-value. Here, eco-value of technology is defined as the advantage of environmental competitiveness in the market. This paper proposes a framework of R&D management of eco-technology (RDMOET, consisting of: (1 future research for sustainability; (2 making an original eco-theme portfolio and roadmap; (3 gap analysis and implementation of new eco-themes; and (4 eco-value evaluation. (1 and (4 are new processes compared with conventional R&D management. Through practice at the Corporate R&D Center of Toshiba Corporation, the usefulness of the proposed framework is verified from the viewpoint of not only technological eco-innovation, but also that of organizational learning for environmental sustainability.

Energy R and D programme: energy conservation research. Survey of results (1975-1979) and compilation of selected new projects (1979-1983)

Energy Technology Data Exchange (ETDEWEB)

Zegers, P [ed.

1981-01-01

Results obtained in the European Communities Energy Conservation Research and Development (R and D) Program are presented. Energy Conservation R and D was executed in the following subsectors: improved insulation of buildings; use of heat pumps; urban transport; residual heat recovery; materials recycling; production of energy from waste; industrial processes; and storage of secondary energy. Summaries are presented for information gained from the research projects. Then, separate abstracts for all final reports (96), contract numbers, and the authors are given. (MCW)

Spanish electrical sector and Nuclear R and D

International Nuclear Information System (INIS)

Salve, R.

1994-01-01

This article presents the global situation of the R and D in Nuclear Sector. The author proposes they way to obtain the best results in the R and D area. This way is: 1.- Clear objectives 2.- Integration of R and D into the enterprise plan. 3.- More decision capacity 4.- To plan the long-term benefits

R and D status for NPP life management in Korea

Energy Technology Data Exchange (ETDEWEB)

Kim, Tae Ryong [Korea Electric Power Research Institute, Daejeon (Korea, Republic of)

2009-04-15

The economical benefits may be achieved by the plant life management (PLiM) as well as structural integrity of the critical components of NPP. Systems, structures and components (SSC) of NPP are designed to have safety margins in design stage, and being operated with operational margins. As the plant gets older and older, however, aging of SSC occurs and some of SSC may be sometimes failed due to the unexpected aging mechanisms in design stage. Most countries which have operated NPP have their own R and D programs to establish proper countermeasures against the aging and degradation of SSC, The well known program are materials reliability program (MRP) and steam generator management program (SGMP) of EPRI. In Korea, we also have our own R and D programs for the plant life management. In this paper, the present status of the R and D programs will be introduced. Long term operation of a nuclear power plant is one of the goals that the plant wants to achieve, which may be possible as long as the plant safety is maintained and the economical benefits is expected. The economical benefits may be achieved by the plant life management (PLiM) activities. Many R and D activities related to PLiM have been carried out and implemented to Korean NPP, Kori Unit 1 and Wolsong Unit 1 in particular, for the long term operation beyond their original design lives. Those activities include PLiM study, PSR, SGMP, MRP, thinned pipe management program, study on dissimilar metal welds, aging monitor etc. With the results of R and D activities, continued operation of Kori Unit 1 was successfully started from January 17, 2008 for next 10 years beyond its design life. It must be a landmark of 30 years history of nuclear power generation in Korea. Subsequently Wolsong Unit 1 is also expected to start its continued operation when the replacement of pressure tubes and feeders are completed in 2009. Many countries have plans to build new reactors or to extend the life of operating plants.

R and D status for NPP life management in Korea

International Nuclear Information System (INIS)

Kim, Tae Ryong

2009-01-01

The economical benefits may be achieved by the plant life management (PLiM) as well as structural integrity of the critical components of NPP. Systems, structures and components (SSC) of NPP are designed to have safety margins in design stage, and being operated with operational margins. As the plant gets older and older, however, aging of SSC occurs and some of SSC may be sometimes failed due to the unexpected aging mechanisms in design stage. Most countries which have operated NPP have their own R and D programs to establish proper countermeasures against the aging and degradation of SSC, The well known program are materials reliability program (MRP) and steam generator management program (SGMP) of EPRI. In Korea, we also have our own R and D programs for the plant life management. In this paper, the present status of the R and D programs will be introduced. Long term operation of a nuclear power plant is one of the goals that the plant wants to achieve, which may be possible as long as the plant safety is maintained and the economical benefits is expected. The economical benefits may be achieved by the plant life management (PLiM) activities. Many R and D activities related to PLiM have been carried out and implemented to Korean NPP, Kori Unit 1 and Wolsong Unit 1 in particular, for the long term operation beyond their original design lives. Those activities include PLiM study, PSR, SGMP, MRP, thinned pipe management program, study on dissimilar metal welds, aging monitor etc. With the results of R and D activities, continued operation of Kori Unit 1 was successfully started from January 17, 2008 for next 10 years beyond its design life. It must be a landmark of 30 years history of nuclear power generation in Korea. Subsequently Wolsong Unit 1 is also expected to start its continued operation when the replacement of pressure tubes and feeders are completed in 2009. Many countries have plans to build new reactors or to extend the life of operating plants.

Results of a Technical Review of the U.S. Climate Change Technology Program's R&D Portfolio

Energy Technology Data Exchange (ETDEWEB)

Brown, Marilyn A [ORNL

2006-07-01

The U.S. Climate Change Technology Program (CCTP) is a multi-agency planning and coordinating entity, led by the U.S. Department of Energy that aims to accelerate the development and facilitate the adoption of technologies to address climate change. In late 2005, CCTP asked Oak Ridge National Laboratory and Energetics Incorporated to organize and coordinate a review of the CCTP R&D portfolio using structured workshops. Each workshop focused on one of CCTP's six strategic goals: 1.Reduce emissions from energy end-use and infrastructure 2.Reduce emissions from energy supply 3.Capture and sequester carbon dioxide 4.Reduce emissions of non-CO2 greenhouse gases (GHG) 5.Improve capabilities to measure and monitor GHG emissions 6.Bolster basic science contributions to technology development To promote meaningful dialogue while ensuring broad coverage, a group of broadly experienced professionals with expertise in fields relevant to each CCTP goal were asked to participate in the portfolio reviews and associated workshops. A total of 75 experts participated in the workshops; 60 of these participants represented non-Federal organizations. This report summarizes the findings of the workshops and the results of the Delphi assessment of the CCTP R&D portfolio.

D$^{6}$ℛ$^{4}$ amplitudes in various dimensions

CERN Document Server

Pioline, Boris

2015-01-01

Four-graviton couplings in the low energy effective action of type II string vacua compactified on tori are strongly constrained by supersymmetry and U-duality. While the $R^4$ and $D^4 R^4$ couplings are known exactly in terms of Langlands-Eisenstein series of the U-duality group, the $D^6 R^4$ couplings are not nearly as well understood. Exploiting the coincidence of the U-duality group in $D=6$ with the T-duality group in $D=5$, we propose an exact formula for the $D^6 R^4$ couplings in type II string theory compactified on $T^4$, in terms of a genus-two modular integral plus a suitable Eisenstein series. The same modular integral computes the two-loop correction to $D^6 R^4$ in 5 dimensions, but here provides the non-perturbative completion of the known perturbative terms in $D=6$. This proposal hinges on a systematic re-analysis of the weak coupling and large radius of the $D^6 R^4$ in all dimensions $D\\geq 3$, which fills in some gaps and resolves some inconsistencies in earlier studies.

International R&D Spillovers and Marginal Social Returns on R&D

NARCIS (Netherlands)

Sterken, Elmer; Ogawa, Kazuo; Tokutsu, Ichiro

2016-01-01

We analyze the impact of international R&D spillovers on recipient countries in terms of social and private returns. We divide the aggregate R&D stock by the business, government and education sectors and examine the impact on Total Factor Productivity. We endogenize the accrual of the R&D stocks by

Andra - R and D activity report 2015

International Nuclear Information System (INIS)

2016-09-01

The National Radioactive Waste Management Agency (Andra), created in 1979 within the CEA, was established by the December 1991 Waste Act as a public body in charge of the long-term management of all radioactive waste, under the supervision of the Ministry of Ecology, Energy, Sustainable Development and the Sea (formerly the Ministry of Industry and the Ministry of Environment), and the Ministry of Research. Its 3 basic missions were extended and their funding secured through the 2006 Planning Act: - a R and D mission to propose safe long-term solution for radioactive waste without current disposal system; this mission includes long-term storage, since the 2006 Planning Act, in order to propose interim solutions while final ones are being studied, - an industrial mission concerning, on one hand, waste acceptance criteria and control and, on the other hand, siting, construction, operation, closure and monitoring of repositories, - an information mission, notably through the regular publication of the National Inventory of radioactive materials and waste. This document is the 2015 annual activity report of the Andra for the R and D mission. It presents: the 2015 R and D highlights, the R and D at the service of Andra's projects and activities (towards Cigeo's industrial development, main R and D results for a key step of the low level-long living wastes project, R and D at the service of surface facilities operation), the Andra partnership with the scientific community (mobilization, PhDs, projects investment, conference and workshops participation), and the restructuring of the scientific governance of the Andra. The patents issued by the Andra and the defended PhD Theses are listed in the appendix

R&D Project Valuation Considering Changes of Economic Environment: A Case of a Pharmaceutical R&D Project

Directory of Open Access Journals (Sweden)

Jung Ho Park

2018-03-01

Full Text Available R&D project valuation is important for effective R&D portfolio management through decision making, related to the firm’s R&D productivity, sustainable management. In particular, scholars have emphasized the necessities of capturing option value in R&D and developed methods of real option valuation. However, despite suggesting various real option models, there are few studies on simultaneously employing mean-reverting stochastic process and Markov regime switching to describe the evolution of cash flow and to reflect time-varying parameters resulting from changes of economic environment. Therefore, we suggest a mean-reverting binomial lattice model under Markov regime switching and apply it to evaluate clinical development with project cases of the pharmaceutical industry. This study finds that decision making can be different according to the regime condition, thus the suggested model can capture risks caused by the uncertainty of the economic environment, represented by regime switching. Further, this study simulates the model according to rate parameter from 0.00 to 1.00 and risk-free interest rates for regimes 1 and 2 from ( r 1 = 4%, r 2 = 2% to ( r 1 = 7%, r 2 = 5%, and confirms the rigidity of the model. Therefore, in practice, the mean-reverting binomial lattice model under Markov regime switching proposed in this study for R&D project valuation contributes to assisting company R&D project managers make effective decision making considering current economic environment and future changes.

Energy R and D. Conservation planning and management should be strengthened

International Nuclear Information System (INIS)

Hale, Richard A.; Fishkin, Christine M.B.; MacLeod, Molly W.; Davis, Alphonse R.; Crawford, John T.; Dowd, Leonard L.; Sisson, John W.; Sugimura, Richard H.

1990-07-01

Increased energy efficiency can lessen our dependence on imported oil, reduce environmental problems associated with the use of fossil fuels, and enhance the competitive position of U.S. companies internationally. Following a decade in which conservation R and D program funding declined by more than 50 percent, the Secretary of Energy has said that energy conservation will be given increased priority in DOE. Increased priority for DOE's energy efficiency R and D program would support interim DOE National Energy Strategy (NES) report findings. DOE's interim NES report said that broad public support exists for increasing energy efficiency and protecting the environment from the effects of energy production and use. In the 1970s and 1980s, the DOE conservation R and D program produced some commercially successful technologies, such as fluorescent lighting advances and low emissivity window coatings, that are providing energy savings and are expected to provide substantial savings in the future. In the early 1980s energy conservation R and D funding and staff were reduced substantially, reflecting the administration's view that conservation research should be conducted primarily by the private sector. Since the large cutback, funding has been relatively stable, it was $346 million in 1980, $152 million in 1982, and $149 million in 1990. The 1991 budget request reflects a 9-percent program reduction compared with the prior year's appropriations. Since 1983, DOE's Office of Conservation has used a long-term planning process to produce an energy conservation multi-year R and D plan. However, the plan and the planning process could be strengthened to more fully meet the needs of policy makers. For example, the plan's usefulness and credibility would be improved if it provided detailed information on individual projects. Also, the planning process does not include systematic project reviews at DOE headquarters or use a uniform project prioritization methodology to rank

The EUDET research infrastructure for detector R and D

International Nuclear Information System (INIS)

Gregor, Ingrid-Maria

2010-01-01

EUDET is an initiative supported by the European Union to improve infrastructures for detector R and D, in particular for the International Linear Collider (ILC). The project is focused on providing support for larger scale prototype experiments as well as on facilitating collaborative efforts. It encompasses developments for vertex detectors, gaseous and silicon tracking, and highly granular electromagnetic and hadron calorimeters. In total 32 European institutes participate in the project. Twenty-seven other institutes in Europe and abroad are associated members and linked to the progress and later exploitation of the infrastructures. EUDET is closely linked to the international R and D collaborations for a future ILC detector. The R and D infrastructure program is described and some results of the R and D efforts are presented.

Final report for the 'Melt-Vessel Interactions' Project. European Union R and TD Program 4th Framework. MVI project final research report

Energy Technology Data Exchange (ETDEWEB)

Sehgal, B.R.; Dinh, T.N.; Nourgaliev, R.R.; Bui, V.A.; Green, J.; Kolb, G.; Karbojian, A.; Theerthan, S.A.; Gubaidulline, A. [Royal Inst. of Tech., Stockholm (Sweden). Div. of Nuclear Power Safety; Helle, M.; Kymaelaeinen, O.; Tuomisto, H. [IVO Power Engineering Ltd., Vantaa (Finland); Bonnet, J.M.; Rouge, S.; Narcoux, M.; Liegeois, A. [CEA - Grenoble (France); Turland, B.D.; Dobson, G.P. [AEA Technology plc, Dorchester (United Kingdom); Siccama, A. [ECN Nuclear Research, Petten (Netherlands); Ikonen, K. [VTT Energy, Helsinki (Finland); Parozzi, F. [ENEL - SRI/PAM/GRA, Segrate, MI (Italy); Kolev, N. [Siemens AG, Erlangen (Germany); Caira, M. [Univ. of Roma (Italy)

1999-04-01

The Melt Vessel Interaction (MVI) project is concerned with the consequences of the interactions that a core melt, generated during a postulated severe accident in a light water reactor, may have with the pressure vessel. In particular, the issues concerned with the failure of the vessel bottom head are the focus of the research. The specific objectives of the project are to obtain data and develop validated models, which could be applied to prototypic plants, and accident conditions, for resolution of issues related to the melt vessel interactions. The project work has been performed by nine partners having varied responsibility. The work included a large number of experiments, with simulant materials, whose observations and results are employed, respectively, to understand the physical mechanisms and to develop validated models. Applications to the prototypic geometry and conditions have also been performed. This report is volume 1 of the Final Report for the Project, in which a summary of the progress achieved in the experimental program is provided. We have, however, included some aspects of the modeling activities. Volume 2 of the Final report describes the progress achieved in the modeling program. The progress achieved in the experimental and modeling parts of the Project has led to the resolution of some of the issues of melt vessel interaction. Considerable progress was also achieved towards resolution of the remaining issues.

Synthesis and physico-chemical properties of (R,S)-6-ditrideuteriomethylamino-4,4-diphenylheptan-3-one hydrochloride (methadone-d6)

International Nuclear Information System (INIS)

Gerardy, B.M.; Poupaert, J.H.; Vandervorst, D.; Dumont, P.; Declerq, J.-P.; Meerssche, M. van; Portoghese, P.S.

1985-01-01

A reaction sequence is described to synthesize (R,S)-6-ditrideuteriomethylamino-4,4-diphenylheptan-3-one hydrochloride (methado-ne-d 6 .HC1) in 10.5% overall yield starting from dimethylamine-d 6 hydrochloride. While methadone-d 6 .HC1 had rather similar physicochemical properties compared to methadone.HC1 in the solid phase, a divergent behaviour was observed in solution (pKa, chromatographic and 13 C-NMR data). A higher basicity along with a more important hydrophilicity were observed for the d 6 -derivative. A 13 C-NMR study showed significant differences in the 13 C chemical shifts, which were attributed in part to the intrinsic nature of D itself and in part to a conformational perturbation. The longer duration of antinociceptive action, along with higher tsub(1/2) and clearance, and the depression of the metabolic N-demethylation process were the only biological properties modified by the deuteration. (author)

Retrospective Benefit-Cost Evaluation of U.S. DOE Wind Energy R&D Program: Impact of Selected Energy Technology Investments

Energy Technology Data Exchange (ETDEWEB)

Pelsoci, Thomas M. [Delta Research Co., Evanston, IL (United States)

2010-06-01

This benefit-cost analysis focuses on the DOE Wind Energy Program's public sector R&D investments and returns. The analysis accounts for the program's additionality – that is, comparing what has happened as a result of the program to what would have happened without it. The analysis does not address the return on the investments of private companies ("private returns"). Public returns on the program's investments from 1976 to 2008 are identified and analyzed using retrospective analysis.

Status of beryllium R and D in Japan

International Nuclear Information System (INIS)

Kawamura, H.; Ishida, K.

2004-01-01

Recently, several R and D program of beryllium for fusion are being promoted in Japan and community of beryllium study is growing up. In the R and D area of beryllium for solid breeding blanket, major subjects are beryllide application for prototype reactor, lifetime evaluation of neutron multiplier, impurity effect of beryllium and recycling of irradiated beryllium. Especially, the study of beryllide application has significant progress in these two years. The basic properties such as tritium inventory, oxidation behavior, steam interaction for stoichiometric Be 12 Ti fabricated by HIP (Hot Isostatic Pressing) have been studied and some advantages against beryllium were made clear. For manufacturing technology development, phase diagram and ductility improvement have been studied. And, Be 12 Ti pebbles with the improved microstructure were successfully fabricated by Rotating Electrode Process. In order to enhance the R and D activities, the R and D network consisted of industries, universities and laboratories in all Japan have been organized. Many collaboration and information exchange strongly promotes the R and D and some projects for commercial application have been launched form these activities. Also international collaborative project such as IEA and ISTC have been launched or planned. Recent result of R and D in Japan is described on this paper. (author)

Roadmapping - A Tool for Strategic Planning and Leveraging R and D completed by other Agencies

International Nuclear Information System (INIS)

Collins, J. W.

2002-01-01

The Department of Energy (DOE) is responsible for management of the environmental legacy of the nation's nuclear weapons and research program. This is the largest, most complex environmental cleanup program in the world. The issues and problems encountered in this program create the need to develop many scientific and technological solutions. To be effective, the process used to create these solutions must be well coordinated through DOE's Environmental Management program, the rest of DOE, and other Federal agencies. Roadmapping is one strategic planning tool to provide the needed coordination. Past roadmapping accomplishments include: (1) Issuance of the Draft EM Roadmapping Guidance; (2) Issuance of the EM R and D Program Plan and Strategic Plan which established the direction for Roadmapping; (3) Issuance of the OST Management Plan which calls out Roadmapping as a key tool in EM Research and Development (R and D) Strategic Planning; (4) Completion of or progress on key EM Roadmaps, i.e., Savannah River High Level Waste (HLW) Salt Dispositioning Roadmaps, Hanford Groundwater/Vadose Zone Roadmap, Robotics and Intelligent Machines Critical Technology Roadmap, Complex-Wide Vadose Zone Roadmap, Long-Term Stewardship Preliminary Roadmap, Hydrogen Gas Generation R and D Plan (Roadmap), Idaho National Engineering and Environmental Laboratory (INEEL) Sodium Bearing Waste Dispositioning Roadmap, INEEL Voluntary Consent Order Tanks Characterization Roadmap, INEEL Vadose Zone/Groundwater Roadmap, Calcine Treatment Alternatives Roadmap. These efforts represent a great start; however, there is more to be accomplished in using Roadmapping as a tool for planning strategic initiatives and in coordinating the R and D performed by multiple federal agencies

R and D on seismic emergency information system

International Nuclear Information System (INIS)

2001-06-01

After the Great Hansin-Awaji Earthquake Disaster occurred in 1995, the Science and Technology Agency commenced 'Frontier Research Program on Earthquake' in FY1996. As a part of this research program, four-year program on 'Research on Real-time Earthquake Information Transmission' has been carried out at JAERI since FY1997. Through the experience of the above earthquake disaster, the importance of accurate and prompt seismic information transmission immediately after the occurrence of the earthquake has been recognized from the viewpoint of disaster mitigation. Under this circumstance, the main activity in Real-time Earthquake Information Transmission Research at JAERI has been placed on the development of a seismic emergency information system. In order to respond to the above R and D, Seismic Emergency Information System Research Team was organized in JAERI in FY1998. In the meantime, a part of this R and D program is performed under the coordinated research between JAERI and NIED (National Research Institute for Earth Science and Disaster Prevention). This report summarizes the results of four years program from FY1997 to FY2000 on the above R and D. The R and D has been conducted involving the latest progress in earthquake engineering with regard to estimation techniques on the hypocenter, fault and earthquake motion parameters and in Information Technologies. The R and D was divided into two parts, i.e., development of the basic system and application system. In the basic system, earthquake information with 500 m square mesh in a local area can be estimated and transmitted in a few minutes. In the application system, the concept of the disaster management system which consists of user site and disaster information center and is capable of mutual information transmission has been established. A prototype of the application system, which include the basic system in the disaster information center, has been developed. Test operation of the basic system in being

New effective coupled F((4)R, φ) modified gravity from f((5)R) gravity in five dimensions

International Nuclear Information System (INIS)

Madriz Aguilar, Jose Edgar

2015-01-01

Using some ideas of the Wesson induced matter theory, we obtain a new kind of F( (4) R, φ) modified gravity theory as an effective four-dimensional (4D) theory derived from f( (5) R) gravity in five dimensions (5D). This new theory exhibits a different matter coupling than the one in BBHL theory. We show that the field equations of the Wesson induced matter theory and of some brane-world scenarios can be obtained as maximally symmetric solutions of the same f( (5) R) theory. We found criteria for the Dolgov-Kawasaki instabilities for both the f( (5) R) and the F( (4) R, φ) theories. We demonstrate that under certain conditions imposed on the 5D geometry it is possible to interpret the F( (4) R, φ) theory as a modified gravity theory with dynamical coefficients, making this new theory a viable candidate to address the present accelerating cosmic expansion issue. Matter sources in the F( (4) R, φ) case appear induced by the 5D geometry without the necessity of the introduction of matter sources in 5D. (orig.)

Neutral beam injection status and R and D needs for TNS

International Nuclear Information System (INIS)

Becraft, W.R.

1978-01-01

The Next Step (TNS) Program, established by DOE at ORNL in early 1976, has as one of its key objectives to provide a means of focusing the R and D efforts in the National Fusion Program toward the achievement of economically viable tokamak fusion reactors. One part of a draft program plan issued in December, 1977, specifically addressed the R and D needs of each of the major subsystems of a tokamak fusion device that would be extrapolatable to a reactor. Included as a major subsystem was plasma heating. It is the purpose of the effort reported here to continue the assessment started and to update and expand its findings. The goal continues to be to define, justify and order the required R and D programs that would ensure neutral injection systems for heating tokamak plasmas to be available for a TNS-type machine operation start assumed to be in 1990. Particle injection is covered here. Wave heating is being addressed in a separate, parallel effort

R&D 100 Awards | NREL

Science.gov (United States)

R&D 100 Awards R&D 100 Awards NREL has won 61 R&D 100 Awards. Widely recognized as the Oscars of Invention, the R&D 100 Awards are presented by R&D Magazine to identify and celebrate the top technological advances of the year. Recent R&D 100 Awards 2016 NREL engineers Chuck Booten

The Need for an R&D and Upgrade Program for CMS Software and Computing

CERN Document Server

Elmer, Peter; Stenson, Kevin; Wittich, Peter

2013-01-01

Over the next ten years, the physics reach of the Large Hadron Collider (LHC) at the European Organization for Nuclear Research (CERN) will be greatly extended through increases in the instantaneous luminosity of the accelerator and large increases in the amount of collected data. Due to changes in the way Moore's Law computing performance gains have been realized in the past decade, an aggressive program of R&D is needed to ensure that the computing capability of CMS will be up to the task of collecting and analyzing this data.

Multi-technology option strategy for long term R and D programs on plutonium technologies. Minimizing proliferation risks and preparing for the future

International Nuclear Information System (INIS)

Suzuki, Tatsujiro

1997-01-01

Plutonium programs worldwide are now facing major economic, political and technical challenges. New strategies need to address two distinctive global concerns: minimizing proliferation risks associated with plutonium use, and keeping the options alive to prepare for uncertain energy future. In order to meet those challenges, this paper proposes the introduction of 'multi-technology option strategy'. Such strategy is designed to keep so-called 'technological readiness' state of plutonium technologies worldwide without committing to a fixed technology option and exploring more innovative various technology options. This paper also suggests that such R and D programs can be coordinated and shared among nations that are interested in future plutonium use, and such cooperation can improve transparency of sensitive R and D programs. (author)

Status of the French R/D program on the severe accident issue to develop Gen IV SFRs - 15373

International Nuclear Information System (INIS)

Serre, F.; Bertrand, F.; Journeau, C.; Suteau, C.; Verwaede, D.; Schmitt, D.; Farges, B.

2015-01-01

The ASTRID reactor (Advanced Sodium Technological Reactor for Industrial Demonstration) is a technological demonstrator designed by the CEA with its industrial partners, with very high levels of requirements. In the ASTRID project, the safety objectives are to prevent core melting, in particular by the development of an innovative core with complementary safety prevention devices, and to enhance the reactor resistance to severe accident by design. To mitigate the consequences of hypothetical core melting situations, specific dispositions or mitigation devices will be added to the core and to the reactor. It is also required to provide a robust safety demonstration (with high level of confidence). Therefore a new approach for severe accident issue has been defined: to the well-known 'lines of defense' method, a 'lines of mitigation' method is added. To meet these ASTRID, or future SFR, requirements, a large R/D program was launched in the Severe Accident domain, with a large number of partners. This paper will present the status of the CEA R/D related to the SFR Severe Accident issue, the collaboration framework (with industrial partners and R/D foreign organizations), and the future R/D plans to support the ASTRID project and possible developments for future Gen IV commercial SFR. (authors)

IL-1R and MyD88 signalling in CD4+ T cells promote Th17 immunity and atherosclerosis.

Science.gov (United States)

Engelbertsen, Daniel; Rattik, Sara; Wigren, Maria; Vallejo, Jenifer; Marinkovic, Goran; Schiopu, Alexandru; Björkbacka, Harry; Nilsson, Jan; Bengtsson, Eva

2018-01-01

The role of CD4+ T cells in atherosclerosis has been shown to be dependent on cytokine cues that regulate lineage commitment into mature T helper sub-sets. In this study, we tested the roles of IL-1R1 and MyD88 signalling in CD4+ T cells in atherosclerosis. We transferred apoe-/-myd88+/+ or apoe-/-myd88-/- CD4+ T cells to T- and B-cell-deficient rag1-/-apoe-/- mice fed high fat diet. Mice given apoe-/-myd88-/- CD4+ T cells exhibited reduced atherosclerosis compared with mice given apoe-/-myd88+/+ CD4+ T cells. CD4+ T cells from apoe-/-myd88-/- produced less IL-17 but similar levels of IFN-γ. Treatment of human CD4+ T cells with a MyD88 inhibitor inhibited IL-17 secretion in vitro. Transfer of il1r1-/- CD4+ T cells recapitulated the phenotype seen by transfer of myd88-/- CD4+ T cells with reduced lesion development and a reduction in Th17 and IL-17 production compared with wild type CD4+ T cell recipients. Relative collagen content of lesions was reduced in mice receiving il1r1-/- CD4+ T cells. We demonstrate that both IL1R and MyD88 signalling in CD4+ T cells promote Th17 immunity, plaque growth and may regulate plaque collagen levels. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2017. For permissions please email: journals.permissions@oup.com.

ITER technology R and D during the EDA

International Nuclear Information System (INIS)

Mizoguchi, T.

2001-01-01

A short overview of the ITER technology R and D achievements is presented. It includes R and D programme in the area of superconducting magnets, L-1 central solenoid model coil, L-2 toroidal field model coil, L-3 vacuum vessel sector, L-4 blanket module, L-5 divertor cassette, L-6 blanket and L-7 divertor remote handling systems. In addition to the seven large R and D projects, development of components for fuelling, pumping, tritium processing, heating/current drive, power supplies and plasma diagnostics, as well as safety-related R and D have significantly progressed

Schumpeterian growth theory and nuclear R and D

International Nuclear Information System (INIS)

Jeong, H. S.; Yun, S. W.

2001-01-01

The Schumpeterian growth theory with technology innovation and the 4th generation R and D system to build the efficient R and D system are analyzed and some important factors to do practice in the current nuclear R and D are summarized. The factors are asserted to be mentioned in this paper are twofold: first, the necessity of current nuclear R and D system improvement and of national innovation system are described in macroscopic point of view; and second, the necessity of dominant technology and technology diffusion and internal architecturing and forming capability are described in microscopic point of view

Offshoring R&D

DEFF Research Database (Denmark)

Hansen, Zaza Nadja Lee; Rasmussen, Lauge Baungaard

2010-01-01

Companies are increasingly offshoring R&D activities. Many firms, however, experience difficulties related to virtual teamwork across cultures and time zones. The research question is: How does increasing R&D offshoring impact transparency of communication structures and knowledge sharing? Using...... case studies from Danish multinational corporations with R&D activities in China, India or Eastern Europe this paper analyses the impact observed in these companies in regard to communication structures and knowledge sharing in management of offshored R&D activities. The findings show that companies...... attempt to increase transparency through formalisation of knowledge and clear communication structures. However, the influence of tacit knowledge, horizontal communication and culture seem largely overlooked. Therefore the authors suggest a context based approach to transparency accustomed...

Establishing a framework to implement 4D XCAT Phantom for 4D radiotherapy research

Directory of Open Access Journals (Sweden)

Raj K Panta

2012-01-01

Conclusions: An integrated computer program has been developed to generate, review, analyse, process, and export the 4D XCAT images. A framework has been established to implement the 4D XCAT phantom for 4D RT research.

Project X Accelerator R and D Plan

International Nuclear Information System (INIS)

2008-01-01

Project X is a high intensity proton facility conceived to support a world-leading program in neutrino and flavor physics over the next two decades at Fermilab. Project X is an integral part of the Fermilab Roadmap as described in the Fermilab Steering Group Report. Project X is based on an 8 GeV superconducting H-linac, paired with the existing (but modified) Main Injector and Recycler Ring, to provide in excess of 2 MW of beam power throughout the energy range 60-120 GeV, simultaneous with at least 100 kW of beam power at 8 GeV. The linac utilizes technology in common with the ILC over the energy range 0.6-8.0 GeV. Beam current parameters can be made identical to ILC resulting in identical rf generation and distribution systems. This alignment of ILC and Project X technologies allows for a shared development effort. The initial 0.6 GeV of the linac draws heavily on technology developed by Argonne National Laboratory for a facility for rare isotope beams. It is anticipated that the exact configuration and operating parameters of the linac will be defined through the R and D program and will retain alignment with the ILC plan as it evolves over this period. Utilization of the Recycler Ring as an H - stripper and accumulator ring is the key element that provides the flexibility to operate the linac with the same beam parameters as the ILC. The linac operates at 5 Hz with a total of 5.6 x 10 13 H - ions delivered per pulse. H - are stripped at injection into the Recycler in a manner that 'paints' the beam both transversely and longitudinally to reduce space charge forces. Following the 1 ms injection, the orbit moves off the stripping foil and circulates for 200 msec, awaiting the next injection. Following three such injections a total of 1.7 x 10 14 protons are transferred in a single turn to the Main Injector. These protons are then accelerated to 120 GeV and fast extracted to a neutrino target. The Main Injector cycle takes 1.4 seconds, producing approximately 2

CERN openlab: Engaging industry for innovation in the LHC Run 3-4 R&D programme

Science.gov (United States)

Girone, M.; Purcell, A.; Di Meglio, A.; Rademakers, F.; Gunne, K.; Pachou, M.; Pavlou, S.

2017-10-01

LHC Run3 and Run4 represent an unprecedented challenge for HEP computing in terms of both data volume and complexity. New approaches are needed for how data is collected and filtered, processed, moved, stored and analysed if these challenges are to be met with a realistic budget. To develop innovative techniques we are fostering relationships with industry leaders. CERN openlab is a unique resource for public-private partnership between CERN and leading Information Communication and Technology (ICT) companies. Its mission is to accelerate the development of cutting-edge solutions to be used by the worldwide HEP community. In 2015, CERN openlab started its phase V with a strong focus on tackling the upcoming LHC challenges. Several R&D programs are ongoing in the areas of data acquisition, networks and connectivity, data storage architectures, computing provisioning, computing platforms and code optimisation and data analytics. This paper gives an overview of the various innovative technologies that are currently being explored by CERN openlab V and discusses the long-term strategies that are pursued by the LHC communities with the help of industry in closing the technological gap in processing and storage needs expected in Run3 and Run4.

A Methodology for Collective Evaluation and Selection of Industrial R&D Projects

OpenAIRE

Muhittin Oral; Ossama Kettani; Pascal Lang

1991-01-01

This paper proposes a methodology for evaluating and selecting R&D projects in a collective decision setting, especially useful at sectorial and national levels. It consists of two major phases: Evaluation and Selection. The evaluation process repeatedly uses mathematical programming models to determine the "relative values" of a given R&D project from the viewpoint of the other R&D projects. The selection process of R&D projects is based on these "relative values" and is done through a model...

R&D for Collider Beauty Physics at the LHC

CERN Multimedia

2002-01-01

We propose an R&D program for the development of a Beauty trigger and innovative elements of the associated spectrometer. The program builds on the success of the recent S$\\bar{p}$pS collider run of the P238 Collaboration, in which clean signals from beam-beam interactions were observed in a large silicon strip microvertex detector running 1.5~mm from the circulating beams. A continuing successful R&D program of the type proposed could ultimately lead to a collider experiment at the LHC to study CP-violation and rare B decays. \\\\ \\\\ We request a fixed target run during late 1992 in order to demonstrate the effectiveness of a heavy flavour trigger which uses real time digital calculations on silicon strip data, implemented with a data driven processor.

Cast Metals Coalition Technology Transfer and Program Management Final Report

Energy Technology Data Exchange (ETDEWEB)

Gwyn, Mike

2009-03-31

The Cast Metals Coalition (CMC) partnership program was funded to ensure that the results of the Department of Energy's (DOE) metalcasting research and development (R&D) projects are successfully deployed into industry. Specifically, the CMC program coordinated the transfer and deployment of energy saving technologies and process improvements developed under separately funded DOE programs and projects into industry. The transition of these technologies and process improvements is a critical step in the path to realizing actual energy savings. At full deployment, DOE funded metalcasting R&D results are projected to save 55% of the energy used by the industry in 1998. This closely aligns with DOE's current goal of driving a 25% reduction in industrial energy intensity by 2017. In addition to benefiting DOE, these energy savings provide metalcasters with a significant economic advantage. Deployment of already completed R&D project results and those still underway is estimated to return over 500% of the original DOE and industry investment. Energy savings estimates through December 2008 from the Energy-Saving Melting and Revert Reduction Technology (E-SMARRT) portfolio of projects alone are 12 x 1012 BTUs, with a projection of over 50 x 1012 BTUs ten years after program completion. These energy savings and process improvements have been made possible through the unique collaborative structure of the CMC partnership. The CMC team consists of DOE's Office of Industrial Technology, the three leading metalcasting technical societies in the U.S: the American Foundry Society; the North American Die Casting Association; and the Steel Founders Society of America; and the Advanced Technology Institute (ATI), a recognized leader in distributed technology management. CMC provides collaborative leadership to a complex industry composed of approximately 2,100 companies, 80% of which employ less than 100 people, and only 4% of which employ more than 250 people

Recruiting program for the future R and D leader in nuclear science and technology

International Nuclear Information System (INIS)

Kim, Wonho; Kim, Inchul; Min, Hwanki; Park, Jungseung; Jung, Sung Hyon; Jeong, Bitna; Choi, Myound Jong

2012-04-01

The national projects of advanced nuclear system development are underway, however, there was little in their need for human resources in the development of nuclear industry and in the nuclear R and D program for the last 10 years. At the same time, a large portion of well-experienced expert in the national research institute and the industry, are getting old and retired, drastically. They faced an unbalanced situation in their supply and demand of human resources in the field of nuclear science and technology. Bring up the experts such as scientists and engineers in nuclear technology makes an important issue as a national agenda. Regardless of the economically stagnated situation in the country, KAERI(Korea Atomic Energy Research Institute) has hired young nuclear scientists and engineers continuously since 2006 last, in order to substitute the increasing retired experts. However, they need more well-brought-up nuclear scientists and engineers in the near future, as a leader of nuclear science and technology. Through this project, we try to recruit a leader of nuclear science and technology, who can create and carry out the world top class R and D programme

Final results for the excitation function and angular distributions of the 3H(d,n)4He reaction

International Nuclear Information System (INIS)

Tang Hongqing; Zhou Zuying; Qi Bujia; Zhou Chenwei; Du Yanfeng; Xia Haihong; Chen Zemin; Chen Zhenpeng; Chen Yingtang

1998-01-01

The final relative excitation function of the 3 H(d,n) 4 He rection at 0 degree is shown out. For comparison, a curve calculated from Drosg's HI-13 tandem is in progressplotted. The angular distributions of the 3 H(d,n) 4 He reaction at E d =13.36, 16.50 and 19.50 Mev in the center-of-mass system are shown out. A comparison of the legendre polynomial coefficients obtained from the present angular distribution data with Drosg's evaluation are reported

78 FR 70255 - West Virginia: Final Authorization of State Hazardous Waste Management Program Revisions

Science.gov (United States)

2013-11-25

... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 271 [EPA-R03-RCRA-2013-0571; FRL-9903-07-Region 3] West Virginia: Final Authorization of State Hazardous Waste Management Program Revisions AGENCY... final authorization of revisions to its hazardous waste program under the Resource Conservation and...

Photonic Network R&D Activities in Japan-Current Activities and Future Perspectives

Science.gov (United States)

Kitayama, Ken-Ichi; Miki, Tetsuya; Morioka, Toshio; Tsushima, Hideaki; Koga, Masafumi; Mori, Kazuyuki; Araki, Soichiro; Sato, Ken-Ichi; Onaka, Hiroshi; Namiki, Shu; Aoyama, Tomonori

2005-10-01

R&D activities on photonic networks in Japan are presented. First, milestones in current ongoing R&D programs supported by Japanese government agencies are introduced, including long-distance and wavelength division multiplexing (WDM) fiber transmission, wavelength routing, optical burst switching (OBS), and control-plane technology for IP backbone networks. Their goal was set to evolve a legacy telecommunications network to IP-over-WDM networks by introducing technologies for WDM and wavelength routing. We then discuss the perspectives of so-called PHASE II R&D programs for photonic networks over the next 5 years until 2010, by focusing on the report that has been recently issued by the Photonic Internet Forum (PIF), a consortium that has major carriers, telecom vendors, and Japanese academics as members. The PHASE II R&D programs should serve to establish a photonic platform to provide abundant bandwidth on demand, at any time on a real-time basis, through the customer's initiative to promote bandwidth-rich applications, such as grid computing, real-time digital-cinema streaming, medical and educational applications, and network storage in e-commerce.

Two-Way 4D Printing: A Review on the Reversibility of 3D-Printed Shape Memory Materials

Directory of Open Access Journals (Sweden)

Amelia Yilin Lee

2017-10-01

Full Text Available The rapid development of additive manufacturing and advances in shape memory materials have fueled the progress of four-dimensional (4D printing. With the right external stimulus, the need for human interaction, sensors, and batteries will be eliminated, and by using additive manufacturing, more complex devices and parts can be produced. With the current understanding of shape memory mechanisms and with improved design for additive manufacturing, reversibility in 4D printing has recently been proven to be feasible. Conventional one-way 4D printing requires human interaction in the programming (or shape-setting phase, but reversible 4D printing, or two-way 4D printing, will fully eliminate the need for human interference, as the programming stage is replaced with another stimulus. This allows reversible 4D printed parts to be fully dependent on external stimuli; parts can also be potentially reused after every recovery, or even used in continuous cycles—an aspect that carries industrial appeal. This paper presents a review on the mechanisms of shape memory materials that have led to 4D printing, current findings regarding 4D printing in alloys and polymers, and their respective limitations. The reversibility of shape memory materials and their feasibility to be fabricated using three-dimensional (3D printing are summarized and critically analyzed. For reversible 4D printing, the methods of 3D printing, mechanisms used for actuation, and strategies to achieve reversibility are also highlighted. Finally, prospective future research directions in reversible 4D printing are suggested.

U.S. FUEL CYCLE TECHNOLOGIES R&D PROGRAM FOR NEXT GENERATION NUCLEAR MATERIALS MANAGEMENT

Directory of Open Access Journals (Sweden)

M.C. MILLER

2013-11-01

Full Text Available The U.S. Department of Energy's Fuel Cycle Technologies R&D program under the Office of Nuclear Energy is working to advance technologies to enhance both the existing and future fuel cycles. One thrust area is in developing enabling technologies for next generation nuclear materials management under the Materials Protection, Accounting and Control Technologies (MPACT Campaign where advanced instrumentation, analysis and assessment methods, and security approaches are being developed under a framework of Safeguards and Security by Design. An overview of the MPACT campaign's activities and recent accomplishments is presented along with future plans.

Andra - R and D activity report 2016

International Nuclear Information System (INIS)

2017-07-01

The National Radioactive Waste Management Agency (Andra), created in 1979 within the CEA, was established by the December 1991 Waste Act as a public body in charge of the long-term management of all radioactive waste, under the supervision of the Ministry of Ecology, Energy, Sustainable Development and the Sea (formerly the Ministry of Industry and the Ministry of Environment), and the Ministry of Research. Its 3 basic missions were extended and their funding secured through the 2006 Planning Act: - a R and D mission to propose safe long-term solution for radioactive waste without current disposal system; this mission includes long-term storage, since the 2006 Planning Act, in order to propose interim solutions while final ones are being studied, - an industrial mission concerning, on one hand, waste acceptance criteria and control and, on the other hand, siting, construction, operation, closure and monitoring of repositories, - an information mission, notably through the regular publication of the National Inventory of radioactive materials and waste. This document is the 2016 annual activity report of the Andra for the R and D mission. It presents: the 2016 R and D highlights, the R and D at the service of Andra's projects and activities, the Andra partnership with the scientific community, and the scientific governance of the Andra. The patents issued by the Andra and the PhD Theses defended and in progress are listed in the appendix

M4D: a powerful tool for structured programming at assembly level for MODCOMP computers

International Nuclear Information System (INIS)

Shah, R.R.; Basso, R.A.J.

1984-04-01

Structured programming techniques offer numerous benefits for software designers and form the basis of the current high level languages. However, these techniques are generally not available to assembly programmers. The M4D package was therefore developed for a large project to enable the use of structured programming constructs such as DO.WHILE-ENDDO and IF-ORIF-ORIF...-ELSE-ENDIF in the assembly code for MODCOMP computers. Programs can thus be produced that have clear semantics and are considerably easier to read than normal assembly code, resulting in reduced program development and testing effort, and in improved long-term maintainability of the code. This paper describes the M4D structured programming tool as implemented for MODCOMP'S MAX III and MAX IV assemblers, and illustrates the use of the facility with a number of examples

WIPP R and D in situ test program

International Nuclear Information System (INIS)

Tyler, L.D.

1987-01-01

The Waste Isolation Pilot Plant (WIPP) is a Department of Energy (DOE) RandD Facility for the purpose of developing the technology needed for the safe disposal of the United States' defense-related radioactive waste. The in situ test program focus is to provide the models and data to demonstrate the facility performance for isolation of waste at WIPP. The program is defined for the WIPP sealing system, thermal-structural interactions and waste package performance. A number of integrated large-scale underground tests have been operational since 1983 and are ongoing. The tests address the issues of both systems design and long-term isolation performance of the WIPP repository

Report of the review committee on the Fermilab HGQ R and D program

International Nuclear Information System (INIS)

Devred, A.; Anerella, M.; Leroy, D.; Ostojic, R.; Schermer, R.; Vedrine, P.

1999-04-01

This document is the report of the committee which met at Fermi National Accelerator Laboratory on 18 and 19 March 1999 to review the Fermilab R and D program on High Gradient Quadrupole magnets for the Large Hadron Collider Insertion Regions. The promising results of model magnet HGQ05 constitute a significant step forward and provide a solid basis upon which to base the magnet program. Although, the quench performance of magnet HGQ05 shows good progress, it is not yet fully satisfactory and can still be improved. The committee recommends that particular attention be paid to the first training quenches at 1.9 K and that more analyses be carried out to find possible correlations between quench start localization and specific mechanical features. In particular, the committee recommends analyzing in detail collar deflection data that seem to indicate that the first training quenches at 1.9 K may have originated in a region of low azimuthal coil pre-compression. The relative success of magnet HGQ05 and a detailed understanding of the reason behind it should help focus the magnet program on a limited number of clearly identified issues. The magnet program should be revised immediately to incorporate the lessons learned from magnet HGQ05 and to address the most outstanding issues. (authors)

FY 2000 report on the results of the regional consortium R and D project - Regional consortium energy R and D field. First year report. R and D of new composite polymer electrolyte for battery; 2000 nendo chiiki consortium kenkyu kaihatsu jigyo - chiiki consortium energy kenkyu kaihatsu bun'ya. Denchiyo shinki fukugo polymer kei denkaishitsu no kenkyu kaihatsu (dai 1 nendo) seika hokokusho

Energy Technology Data Exchange (ETDEWEB)

NONE

2001-03-01

The development was proceeded with of new composite polymer electrolyte for Li secondary battery. The ultimate target of the development using this electrolyte is to get Li secondary battery markedly improved in safety/reliability which works at low temperature and controls thermal runaway. The composite polymer base electrolyte is composed of high molecular weight polyethylene oxide copolymer, ethylene oxide oligomer and Li salt, and it is finally cross-linked by heat or light. Studies were made in the following 6 fields: 1) R and D of the creation and optimization of new composite polymer electrolyte; 2) R and D of the commercialization of composite polymer electrolyte battery; 3) R and D on the safety of composite polymer electrolyte; 4) study of the synthesis of new electrolyte and catalytic activity of electrolyte-electrode interface; 5) R and D on polymer/oligomer composite electrolyte; and 6) comprehensive investigational research. (NEDO)

NCSU reactor sharing program. Final technical report

International Nuclear Information System (INIS)

Perez, P.B.

1997-01-01

The Nuclear Reactor Program at North Carolina State University provides the PULSTAR Research Reactor and associated facilities to eligible institutions with support, in part, from the Department of Energy Reactor Sharing Program. Participation in the NCSU Reactor Sharing Program continues to increase steadily with visitors ranging from advance high school physics and chemistry students to Ph.D. level research from neighboring universities. This report is the Final Technical Report for the DOE award reference number DE-FG05-95NE38136 which covers the period September 30, 1995 through September 30, 1996

TRIPOLI-4R Version 8 User Guide

International Nuclear Information System (INIS)

Brun, Emeric; Damian, Frederic; Dumonteil, Eric; Hugot, Francois-Xavier; Lee, Yi-Kang; Malvagi, Fausto; Mazzolo, Alain; Petit, Odile; Trama, Jean-Christophe; Visonneau, Thierry; Zoia, Andrea

2013-02-01

TRIPOLI-4 R solves the linear Boltzmann equation for neutrons, photons, electrons and positrons, with the Monte Carlo method, in any 3D geometry. The code uses ENDF format continuous energy cross-sections, from various international evaluations including JEFF-3.1.1, ENDF/B-VII.0, JENDL4 and FENDL2.1. Its official nuclear data library for applications, named CEAV5.1.1, is mainly based on the European evaluation JEFF-3.1.1. TRIPOLI-4 R solves fixed source as well as eigenvalue problems. It has advanced variance reduction methods to address deep penetration issues. Thanks to its robust and efficient parallelism capability, calculations are easily performed on multi-core single units, heterogeneous networks of workstations and massively parallel machines. Additional productivity tools, graphical as well as algorithmic, allow the user to efficiently set its input decks. With its large V and V data base, TRIPOLI-4 R is used as a reference code for industrial purposes, as well as a R and D and teaching tool, for radiation protection and shielding, core physics, nuclear criticality-safety and nuclear instrumentation. TRIPOLI-4 R is a registered trademark of CEA. (authors)

Transforming CyberSecurity R&D within the Department of Energy: Getting Ahead of The Threat

Energy Technology Data Exchange (ETDEWEB)

Frincke, Deborah A.; Catlett, Charlie; Siebenlist, Frank; Strelitz, Richard; Talbot, Ed; Worley, Brian

2008-01-01

This report outlines a preliminary response from DOE researchers to the following three questions: a) what are the key priorities w.r.t. cybersecurity R&D over the next decade? b) what would we recommend, in terms of a program, to address those priorities c) how would a DOE Office of Science program in this area complement other cybersecurity R&D initiatives such as NSF's or other agency programs?

The R.E.D. tools: advances in RESP and ESP charge derivation and force field library building.

Science.gov (United States)

Dupradeau, François-Yves; Pigache, Adrien; Zaffran, Thomas; Savineau, Corentin; Lelong, Rodolphe; Grivel, Nicolas; Lelong, Dimitri; Rosanski, Wilfried; Cieplak, Piotr

2010-07-28

Deriving atomic charges and building a force field library for a new molecule are key steps when developing a force field required for conducting structural and energy-based analysis using molecular mechanics. Derivation of popular RESP charges for a set of residues is a complex and error prone procedure because it depends on numerous input parameters. To overcome these problems, the R.E.D. Tools (RESP and ESP charge Derive, ) have been developed to perform charge derivation in an automatic and straightforward way. The R.E.D. program handles chemical elements up to bromine in the periodic table. It interfaces different quantum mechanical programs employed for geometry optimization and computing molecular electrostatic potential(s), and performs charge fitting using the RESP program. By defining tight optimization criteria and by controlling the molecular orientation of each optimized geometry, charge values are reproduced at any computer platform with an accuracy of 0.0001 e. The charges can be fitted using multiple conformations, making them suitable for molecular dynamics simulations. R.E.D. allows also for defining charge constraints during multiple molecule charge fitting, which are used to derive charges for molecular fragments. Finally, R.E.D. incorporates charges into a force field library, readily usable in molecular dynamics computer packages. For complex cases, such as a set of homologous molecules belonging to a common family, an entire force field topology database is generated. Currently, the atomic charges and force field libraries have been developed for more than fifty model systems and stored in the RESP ESP charge DDataBase. Selected results related to non-polarizable charge models are presented and discussed.

Development of total quality management technology for the establishment of better-quality R and D system

International Nuclear Information System (INIS)

Lee, Young Keun; Lim, Kap Soon; Chang, Ho Il; Kim, Sung Ki; Kim, Jong Suk; Nam, Ji Hee; Kwon, Hyuk Il; Lim, Nam Jin; Cho, Moon Sung; Choi, Se Jin

1996-01-01

The existing total quality management technology(TGMT) has been surveyed to establish R and D quality system by upgrading such TGMT and deploying the concept of quality management. However, there has been a variety of differences on the quality management environments between R and D institutes in advanced countries and KAERI. So the case studies of quality management in advanced countries and those in domestic corporations have been analyzed. Finally, based on this analysis, the questionnaire for all KAERI staff-members has been drawn up for applying TQM to KAERI. 4 tabs., 13 figs., 21 refs. (Author)

Energy technology R&D portfolio management: Modeling uncertain returns and market diffusion

International Nuclear Information System (INIS)

Bistline, John E.

2016-01-01

Highlights: • Analyzes energy R&D decisions with uncertainty in research outcomes and markets. • R&D is shown to be more valuable in second-best planning and policy environments. • Deterministic R&D approaches likely undervalue the optionality of technologies. - Abstract: The allocation of research and development (R&D) funds across a portfolio of programs must simultaneously consider uncertainty from research outcomes and from market acceptance of the resulting technologies. We introduce a stochastic R&D portfolio management framework for addressing both sources of uncertainty and present numerical results for energy technology R&D strategy under uncertainties in climate policy and natural gas prices. Numerical experiments indicate that R&D may be more valuable in second-best planning environments where decision-makers use expected-value approaches, and recourse investments occur after R&D has reduced costs. We also find that deterministic R&D valuation approaches likely overestimate the expected value of R&D success but undervalue the optionality and hedging potential of technologies relative to sequential decision-making approaches under uncertainty. The results also highlight the role of R&D in second-best policy environments.

Efficient production of (R-2-hydroxy-4-phenylbutyric acid by using a coupled reconstructed D-lactate dehydrogenase and formate dehydrogenase system.

Directory of Open Access Journals (Sweden)

Binbin Sheng

Full Text Available (R-2-hydroxy-4-phenylbutyric acid [(R-HPBA] is a key precursor for the production of angiotensin-converting enzyme inhibitors. However, the product yield and concentration of reported (R-HPBA synthetic processes remain unsatisfactory.The Y52L/F299Y mutant of NAD-dependent D-lactate dehydrogenase (D-nLDH in Lactobacillus bulgaricus ATCC 11842 was found to have high bio-reduction activity toward 2-oxo-4-phenylbutyric acid (OPBA. The mutant D-nLDHY52L/F299Y was then coexpressed with formate dehydrogenase in Escherichia coli BL21 (DE3 to construct a novel biocatalyst E. coli DF. Thus, a novel bio-reduction process utilizing whole cells of E. coli DF as the biocatalyst and formate as the co-substrate for cofactor regeneration was developed for the production of (R-HPBA from OPBA. The biocatalysis conditions were then optimized.Under the optimum conditions, 73.4 mM OPBA was reduced to 71.8 mM (R-HPBA in 90 min. Given its high product enantiomeric excess (>99% and productivity (47.9 mM h(-1, the constructed coupling biocatalysis system is a promising alternative for (R-HPBA production.

MAJORANA Neutrinoless Double-Beta Decay DUSEL R and D. Final report

International Nuclear Information System (INIS)

Wilkerson, John F.

2009-01-01

The Majorana research and development is addressing key issues and risks related to the collaboration's goal of undertaking a search for neutrinoless double-beta decay (0νββ) in 76 Ge using an array of hyper-pure Ge-diodes (HPGe). The observation of this decay would provide critical insight into our understanding of neutrinos, yielding definitive evidence that neutrinos are Majorana particles and providing information on the absolute mass of neutrinos. Achieving sensitivities to 0νββ decay half-lives on the order of 10 26 years requires ultra-low backgrounds in the 2039 keV region where a 0νββ decay peak would be observed. The goal of our R and D program has been to demonstrate the feasibility of all components of Majorana and to provide an integrated evaluation framework, allowing for optimization of these components in terms of background, background suppression, and signal detection efficiency and acceptance. This report covers work carried out by Majorana collaboration members at the University of Washington as part of the overall Majorana collaboration activities. Specifically the Majorana group at the University of Washington was involved in moving forward on demonstrating technology for clean large-scale cryostats and mounting the HPGe crystals in low-mass holders. The UW activities included assistance in the procurement and assembly of an electroforming system for large size cryostats, and design and fabrication of prototype crystal mounting hardware.

D R Choudhari

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education. D R Choudhari. Articles written in Resonance – Journal of Science Education. Volume 3 Issue 11 November 1998 pp 94-95 Book Review. Linear Algebra · D R Choudhari · More Details Fulltext PDF ...

Synthesis of carbon-14 labelled cis-malonato [(4R,5R)-4,5-bis(aminomethyl)-2-isopropyl-1,3-dioxolane] platinum(II) (SKI 2053R)

International Nuclear Information System (INIS)

Kim, Dae-Kee; Kim, Youngseok; Rim, Jonggill; Kim, Ganghyeok; Gam, Jongsik; Song, Sungkun; Yoo, Kwanghee; Kim, Key H.

1994-01-01

The synthesis of 14 C-labelled cis-malonato[(4R,5R)-4,5-bis(aminomethyl)-2-isopropyl-1,3-dioxolan e]platinum(II) from [1,4- 14 C] D-tartaric acid is described. The overall radiochemical yield of the product in a eight-step sequence was 23.8% and radiochemical purity was 98.5%. (author)

Internationalisation of R&D

DEFF Research Database (Denmark)

Haakonsson, Stine Jessen; Ujjual, Vandana

2015-01-01

study of a global firm from the most globalised industry in terms of R&D, biotechnology. The article investigates dynamics of internationalisation of R&D in global networks by looking at: 1) the strategic drivers of location, either as a large potential market or as a pool of competencies; and 2......) the evolution of the company and its R&D activities into emerging market locations: India, China and Brazil. Together, these two dimensions constitute the drivers of R&D internationalisation and contribute to the construction of global innovation networks through knowledge augmenting and exploiting strategies....... The article shows how multinational enterprises can use a combination of augmenting and exploiting strategies in emerging markets and hence demonstrates that international R&D activities not always evolve in a sequential and ordered trajectory....

The role of R and D in the nuclear infrastructure

International Nuclear Information System (INIS)

Boulton, J.

1986-04-01

A solid R and D base is an essential component of the nuclear infrastructure, particularly so when a significant degree of self-sufficiency in the nuclear power program is expected. The R and D base can be formed in a number of ways, as centres of excellence in academic institutions, in industrial or utility associations or in national institutions but, as a minimum, a national nuclear research and development laboratory should be in place. The role played by the R and D organizations is a broad one. Some aspects which will be discussed are: (a) to provide a training ground for the scientists and engineers required in an expanding nuclear program, bridging the gap from the academic world of the universities to the industrialized environment, (b) to provide the expertise necessary, at least initially, to adequately receive and absorb the technology which will have to be transferred during the early stages of development of the nuclear power program; this is particularly important for fuel cycle technology, (c) to provide ongoing support during the construction and operation of the nuclear power plants, (d) to establish credibility and seek acceptance in the world-wide research and development community so that the nation can keep abreast with ongoing technological development. (author)

U. S. Fuel Cycle Technologies R and D Program for Next Generation Nuclear Materials Management

International Nuclear Information System (INIS)

Miller, M. C.; Vega, D. A.

2013-01-01

The U. S. Department of Energy's Fuel Cycle Technologies R and D program under the Office of Nuclear Energy is working to advance technologies to enhance both the existing and future fuel cycles. One thrust area is in developing enabling technologies for next generation nuclear materials management under the Materials Protection, Accounting and Control Technologies (MPACT) Campaign where advanced instrumentation, analysis and assessment methods, and security approaches are being developed under a framework of Safeguards and Security by Design. An overview of the MPACT campaign's activities and recent accomplishments is presented along with future plans

Search for Higgs boson production in trilepton and like-charge electron-muon final states with the D0 detector

Czech Academy of Sciences Publication Activity Database

Abazov, V. M.; Abbott, B.; Acharya, B.S.; Kupčo, Alexander; Lokajíček, Miloš

2013-01-01

Roč. 88, č. 5 (2013), "052009-1"-"052009-14" ISSN 1550-7998 R&D Projects: GA MŠk(CZ) LG12006 Institutional support: RVO:68378271 Keywords : anti-p p * interaction * neutral particle * Higgs particle * coupling * electron * muon * dilepton * same sign * final state * D0 * Fermilab Subject RIV: BG - Nuclear, Atomic and Molecular Physics, Colliders Impact factor: 4.864, year: 2013

Structural and thermodynamic properties of new pyrazolo[3,4-d]pyridazinones

Energy Technology Data Exchange (ETDEWEB)

Frizzo, Clarissa P., E-mail: clarissa.frizzo@yahoo.com.br [Núcleo de Química de Heterociclos (NUQUIMHE), Department of Chemistry, Federal University of Santa Maria, UFSM, CEP: 97105-900 Santa Maria, RS (Brazil); Villetti, Marcos A. [Department of Physics, Federal University of Santa Maria, UFSM, CEP: 97105-900 Santa Maria, RS (Brazil); Tier, Aniele Z.; Gindri, Izabelle M.; Buriol, Lilian; Rosa, Fernanda A. [Núcleo de Química de Heterociclos (NUQUIMHE), Department of Chemistry, Federal University of Santa Maria, UFSM, CEP: 97105-900 Santa Maria, RS (Brazil); Claramunt, Rosa M.; Sanz, Dionisia [Departamento de Química Orgánica y Bio-Orgánica, Facultad de Ciencias, UNED, Senda del Rey 9, E-28040 Madrid (Spain); Martins, Marcos A.P. [Núcleo de Química de Heterociclos (NUQUIMHE), Department of Chemistry, Federal University of Santa Maria, UFSM, CEP: 97105-900 Santa Maria, RS (Brazil)

2013-12-20

Highlights: • New 4-substituted-pyrazolo[3,4-d]pyridazinones were synthesized. • Kinetic parameters were determined by Friedmam and Ozawa–Flynn–Wall (OFW) methods. • Compound 2a was more stable than the 2d independent of the model used. • Degradation reaction of 2a and 2d occurs in a single-step. • Amorphous content of 2a and 2d was 48% and 74%, respectively. - Abstract: This work describes the synthesis of new 4-substituted-pyrazolo[3,4-d]pyridazinones (R = C{sub 6}H{sub 5}, 4-F-C{sub 6}H{sub 4}, benzofur-2-yl, CF{sub 3}, 4-NO{sub 2}-C{sub 6}H{sub 4}) from the reaction of dicarbonylpyrazoles with hydrazine hydrate. Solid and solution-state NMR were used to unequivocally assign the structure and identification of the byproduct formed when R = 4-NO{sub 2}-C{sub 6}H{sub 4}. Geometrical features and the intermolecular interactions of compounds were described using single crystal X-ray diffraction. The thermal behavior of the compounds was studied using differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA). Kinetic parameters, such as the activation energy (E{sub a}) and pre-exponential factor (A), were determined as a function of the conversion degree for the thermal decomposition of two compounds, by using the isoconversional methods of Friedman and Ozawa–Flynn–Wall (OFW). The results showed that the E{sub a} for thermal decomposition of compound with R = CF{sub 3} is always higher than for compound with R = C{sub 6}H{sub 5}, independent of the model used (Friedman or OFW), indicating that the former is more stable than the latter. Furthermore, the E{sub a} values for compounds with R = C{sub 6}H{sub 5} and CF{sub 3} are practically constant for all α values from 0.1 to 0.9, indicating the existence of a single-step degradation reaction. The kinetics results also reveal the linear dependence of E{sub a} on the pre-exponential factor. In addition, the 4-substituted-pyrazolo[3,4-d]pyridazinones studied have two types of thermal

Domestic R&D and Offshoring

DEFF Research Database (Denmark)

Junge, Martin; Sørensen, Anders

2017-01-01

survey and register data. No evidence is found for a lower probability of own R&D after offshoring takes place compared to before. Moreover, offshoring does not lead to lower R&D intensity in general. However, firms that offshore R&D activity have larger R&D intensity after offshoring has taken place...

Progress of R and D on seismic emergency information system

International Nuclear Information System (INIS)

2000-09-01

After the Great Hansin-Awaji Earthquake Disaster occurred in 1995, the Science and Technology Agency commenced 'Frontier Research Program on Earthquake' in FY1996. As a part of this research program, four-year program on 'Research on Real-time Earthquake Information Transmission' has been carried out at JAERI since FY1997. Through the experience of the above earthquake disaster, the importance of accurate and prompt seismic information transmission immediately after the occurrence of the earthquake has been recognized from the viewpoint of disaster mitigation. Under this circumstance, the main activity in Real-time Earthquake Information Transmission Research at JAERI has been placed on the development of a seismic emergency information system. In order to respond to the above R and D, Seismic Emergency Information System Research Team was organized in JAERI in FY1998. In the meantime a part of this R and D program is performed under the coordinated research between JAERI and NIED(National Research Institute for Science and Disaster Prevention). This report describes the recent progress of R and D until FY1999. In the R and D, estimation techniques of hypocenter, fault and earthquake motion parameters, in which the latest results in the field of earthquake engineering were involved, were developed. Until the end of FY1999, the main part of the system, in which the above estimation techniques are introduced, is completed. By this system the seismic information is being transmitted using E-mail and homepage through the inter-net. In addition the databases on the estimated earthquake motion parameter distribution under scenario earthquakes and the surface soil amplification function around JAERI-Tokai site are prepared to examine the applicability of the system. (author)

DOE/OE Load as a Resource R&D Overview

Energy Technology Data Exchange (ETDEWEB)

Ton, Dan T. [U.S. Dept. of Energy, Washington, DC (United States)

2011-10-25

DOE R&D and OE’s PSA and ISER programs support OE’s mission to modernize electric grid, enhance energy infrastructure security and reliability, and facilitate recovery from energy supply disruptions.

Lead-based Fast Reactor Development Plan and R&D Status in China

International Nuclear Information System (INIS)

Wu Yican

2013-01-01

• Lead-based fast reactors have good potential for waste transmutation, fuel breeding and energy production, which has been selected by CAS as the advanced reactor development emphasis with the support of ADS program and MFE program. Sharing of technologies R&D is possible among GIF/ADS/Fusion. • The concepts and test strategy of series China lead-based fast reactors (CLEAR) have been developed. The preliminary engineering design and safety analysis of CLEAR-I are underway. • Technology R&D on CLEAR with series lead alloy loops and accelerator-based neutron generator have been constructed or under construction. • CLEAR series reactor design and construction have big challenges, widely international cooperation on reactor design and technology R&D is welcome

Assessing the Impact of the Three-Year Ohio Teen B.R.I.D.G.E.S. AmeriCorps Program.

Science.gov (United States)

Safrit, R. Dale; Schmiesing, Ryan; King, Jeffrey E.; Villard, Judy; Wells, Betty

2003-01-01

Ohio Teen B.R.I.D.G.E.S (Building Responsibility In teen Drivers through Growth in self-Esteem and Safety) was evaluated using 12 focus groups. Program impacts included heightened awareness of vehicular safety issues among teens and communities, enhanced public speaking for youth volunteers, and meaningful leadership and volunteer opportunities…

DOE R and D data tracking base

International Nuclear Information System (INIS)

Horpedahl, L.; Brooks, M.

2000-01-01

This document consists of DOE R and D tracking information for the following topics: Stockpile Readiness Program; Stockpile Reduction Program; Enduring Stockpile Program; Future Stockpile Program; Archiving; Nuclear Component Assessment; Advanced Application; Validation and Verification; Distance and Distributed Computing; DOD Munitions; Performance Assessment; Physics; Los Alamos Meson Physics Facility/Los Alamos Neutron Science Center; Advanced Hydrodynamic Radiography; Systems Engineering; Advanced Manufacturing; Chemistry and Materials; High Explosives; Special Nuclear Mateirals; Tritium; Collaboration with ASCI; Numeric Environment for Weapons Simulation; Target Physics; Theory and Modeling; Target Development; Fabrication and Handling; Other ICF Activities; Development of Predictive Capabilities--Nuclear; Development of Diagnostic Tools--Nuclear; Process Development; and IPPD/Agile Manufacturing

R & D for Indian coal industry - the new agenda

Energy Technology Data Exchange (ETDEWEB)

Ghose, A.K. [Bengal Engineering College, Howrah (India). Dept. of Mining and Geology

1996-07-01

In this paper, an outline of and the R & D agenda for the Indian coal industry, highlighting the national priorities, is suggested. To prepare a viable R & D activity for the coal industry it is necessary to examine, through a priority analysis, the attractiveness and feasibility of research areas which could make significant contributions to the future of Indian coal industry. While meaningful measures per se are difficult to identify, the following criteria may form the basis of such a screening procedure: (1)level of maturity of the existing technology; (2) cost-benefit ratio of R & D; (3) impact on productivity due to incremental changes arising from R & D efforts; and (4) technological maturity of the industry to apply, adopt or adapt the results of R & D. In assessing the overall objectives of any specific portfolio of R & D projects, the costs, time-frame, and benefits will be the prime determinants of the attractiveness. It is necessary to consider both the potential beneficial impacts of a successful R & D programme and also the probability of success within a reasonable time-frame.

Prioritization of R and D programs on probabilistic reactor safety

International Nuclear Information System (INIS)

Husseiny, A.A.

1982-01-01

An interactive computer code based on the multiattribute utility theory has been developed with graphic capabilities to use in selection of probabilistic reactor safety RandD programs. Utility values and proper graphic representation are made through lottery games on the computer terminal. The code is applied to prioritize a set of RandD programs on LWR safety based on attributes including regulatory issues, institutional issues and operation problems. The methodology is described here in detail with its applications. Some of the input includes statistical distributions and subjective judgments on institutional issues. The flexibility of the approach provides a tool for decision makers whether on individual or group level to assess LWR safety priorities and continuously update their strategies

Materials R&D-student internships

Energy Technology Data Exchange (ETDEWEB)

Thompson, R.B.; Jiles, D.C.; Chumbley, L.S. [Iowa State Univ., Ames, IA (United States)

1995-05-01

This program has as an objective the conduct of programmatic research for the Advanced Industrial Concepts Materials Program while training minority graduate students in the process. Well-known demographics indicate that minorities will constitute an increasing fraction of our future work force. Consequently, efforts have been initiated to increase the fraction of minorities and women who choose technical career paths. Included are a wide ranging set of programs beginning with pre-school education, progressing through efforts to retain students in technical paths in grades K-12 and undergraduate education, and ending with encouraging graduate education. The Materials R & D - Student Internships is a unique approach in the latter category. Here, we have focused on a particular area of applied materials research, the Advanced Industrial Concepts Materials Program. Our goal, then, is to educate minority graduate students in the context of this program. The Ames Laboratory was selected as a site for this pilot project since it is a DOE national laboratory, located on the campus of a major research university, which includes in its research interests programs with a strong technological flavor.

Service-sector Competition, Innovation and R&D

DEFF Research Database (Denmark)

Tingvall, Patrick Gustavsson; Karpaty, Patrik

2011-01-01

The central prediction of the Aghion, Bloom, Blundell and Howitt model is an inverted U-shaped relationship between innovation and competition. The model is built on the assumption of a product market and has not yet been tested on the service sector. Using detailed firm-level data on Swedish...... service-sector firms, we find evidence of an inverse U-shaped relationship for exporting service-sector firms. A further breakdown of innovation expenditures shows that the inverse U-shaped pattern holds for intramural R&D and training, but not for extramural R&D. Finally, the results indicate...... that as competition increases, small firms tend to seek strategic alliances with competitors, whereas large firms tend to reduce collaboration with competitors. The behavior of large firms can partly be due to their superior capacity to handle innovation projects internally, which will become more important...

New effective coupled F({sup (4)}R, φ) modified gravity from f({sup (5)}R) gravity in five dimensions

Energy Technology Data Exchange (ETDEWEB)

Madriz Aguilar, Jose Edgar [Centro Universitario de Ciencias Exactas e ingenierias (CUCEI), Universidad de Guadalajara (UdG), Departamento de Matematicas, Guadalajara, Jalisco (Mexico)

2015-12-15

Using some ideas of the Wesson induced matter theory, we obtain a new kind of F({sup (4)}R, φ) modified gravity theory as an effective four-dimensional (4D) theory derived from f({sup (5)}R) gravity in five dimensions (5D). This new theory exhibits a different matter coupling than the one in BBHL theory. We show that the field equations of the Wesson induced matter theory and of some brane-world scenarios can be obtained as maximally symmetric solutions of the same f({sup (5)}R) theory. We found criteria for the Dolgov-Kawasaki instabilities for both the f({sup (5)}R) and the F({sup (4)}R, φ) theories. We demonstrate that under certain conditions imposed on the 5D geometry it is possible to interpret the F({sup (4)}R, φ) theory as a modified gravity theory with dynamical coefficients, making this new theory a viable candidate to address the present accelerating cosmic expansion issue. Matter sources in the F({sup (4)}R, φ) case appear induced by the 5D geometry without the necessity of the introduction of matter sources in 5D. (orig.)

On $R^4$ terms and MHV amplitudes in N = 5,6 supergravity vacua of Type II superstrings

CERN Document Server

Bianchi, Massimo

2011-01-01

We compute one-loop threshold corrections to $R^4$ terms in N= 5,6 supergravity vacua of Type II superstrings. We then discuss non-perturbative corrections generated by asymmetric D-brane instantons. Finally we derive generating functions for MHV amplitudes at tree level in N = 5, 6 supergravities.

R&D INVESTMENTS AND SPILLOVERS UNDER ENDOGENOUS ABSORPTIVE CAPACITY: COMPETITIVE R&D CANNOT TAKE FULL-ADVANTAGE OF COMPLEMENTARITY IN ABSORPTIVE CAPACITY WHILE COOPERATIVE R&D CAN

Directory of Open Access Journals (Sweden)

Mário A.P.M. Da Silva

2018-03-01

Full Text Available We show that the setting up of general conditions on complementarity in absorptive capacity gives rise to different, if not opposite Nash equilibrium outcomes to those found when absorptive capacity is assumed to be determined only by the similarity of R&D orientations. Firms that cooperate in R&D can take full-advantage of complementarity in R&D by adopting firm-specific R&D paths, which appears to contradict findings and predictions of existing theoretical literature on R&D and spillovers. Oddly, firms competing in R&D cannot gain the most from the potential of complementarity in knowledge by not choosing firm-specific R&D approaches in equilibrium under even milder conditions, which is contrary to another prediction of existing related models.

78 FR 28953 - William D. Ford Federal Direct Loan Program

Science.gov (United States)

2013-05-16

.... Ford Federal Direct Loan Program; Interim Final Rule #0;#0;Federal Register / Vol. 78, No. 95... [Docket ID ED-2013-OPE-0066] RIN 1840-AD13 William D. Ford Federal Direct Loan Program AGENCY: Office of... Secretary amends the William D. Ford Federal Direct Loan Program (Direct Loan Program) regulations to...

R & D STRATEGIC INVESTMENT IN AN ASYMMETRICAL CASE

Institute of Scientific and Technical Information of China (English)

Minggao XUE; Pu GONG

2006-01-01

This article analyzes R & D investment decisions in an asymmetrical case. The investment decisions share three important characteristics. First, the investment is completely irreversible. Second,there are two kinds of uncertainties over the future returns from the investment and over technology in R & D process, respectively. Third, there is strategic competition in the asymmetrical case. This article presents the optimal investment threshold values and the optimal investment rule of high-efficient firm (leader), and shows that the investment threshold values are reduced by competition of two firms.Finally, the mixed investment strategies for two firms, the probability that each firm separately exercises the option to invest, and the probability that two firms simultaneously exercise the option are given in the paper.

Cooperative program on DIII-D

International Nuclear Information System (INIS)

Fowler, T.K.

1991-01-01

The main contribution of the Berkeley group to data has concerned ion temperature profile data reduction and transport analysis using this data. In addition, our graduate students have worked on fundamental aspects of transport theory, under the guidance of the Principal Investigator, to prepare them for productive participation in the D3-D program. One of these students, Q. Nguyen, has written a paper with Drs. Stambaugh and Fowler on divertor design, a subject of increasing urgency for ITER and an area of increasing importance in the D3-D program. Finally, work has been completed on determining upper bounds on fluctuation levels and growth constants, relevant to core plasma transport calculations, using thermodynamic methods. This report contains a brief summary of this work, with emphasis on the accomplishments during the past year

R and D-program ''Watercourse operation''. FoU-Programmet sup V assdragsdrift sup. ; Status report 1988/89

Energy Technology Data Exchange (ETDEWEB)

Berg, G; Faugli, E

1990-10-15

The R and D-program ''watercourse management'' has had two field season, 1988 and 1989. This publication provides status reports for the separate project which constitute the program. The work has been concentrated on raising the level of our knowledge within several fields which are of prime importance for public administration, such as soil water, glaciology, fluvial conditions, problems associated with the working of regulation regimes, consequences of reservoir releases, flood problems, water planning analyses and watercource management. All the projects are briefly described and some include a provisional discussion of results. Where scientific reports have been published, these are referred to. 11 figs., 1 tab., 16 refs.

The UK safeguards R and D support program

International Nuclear Information System (INIS)

Patrick, B.H.; Andrew, G.; Tuley, J.N.

1991-01-01

The UK Safeguards R and D Programme in support of IAEA safeguards was formally initiated in 1981. Funding is provided by HM Government through the Department of Energy, responsibility for managing and carrying out the work being placed in the hands of the UK Atomic Energy Authority The programme covers safeguards in a variety of areas, including reprocessing and enrichment plants, nuclear materials in waste, authentication of facility computer systems, training courses for safeguards inspectors, containment and surveillance, destructive and non-destructive assay techniques and techniques for assessing diversion path analysis. In this paper an overview of the work is presented

Trends & Indicators: NE Universities Still R&D Powerhouses

Science.gov (United States)

Harney, John O.

2011-01-01

New England universities performed more than $4 billion worth of research and development (R&D) in 2009, but the region's share of total R&D performed by all U.S. universities remained at 7.3%, down from more than 10% in the 1980s. The region's university research labs have been world-famous for ideas that breed companies and whole…

Complete genomic sequences for hepatitis C virus subtypes 4b, 4c, 4d, 4g, 4k, 4l, 4m, 4n, 4o, 4p, 4q, 4r and 4t.

Science.gov (United States)

Li, Chunhua; Lu, Ling; Wu, Xianghong; Wang, Chuanxi; Bennett, Phil; Lu, Teng; Murphy, Donald

2009-08-01

In this study, we characterized the full-length genomic sequences of 13 distinct hepatitis C virus (HCV) genotype 4 isolates/subtypes: QC264/4b, QC381/4c, QC382/4d, QC193/4g, QC383/4k, QC274/4l, QC249/4m, QC97/4n, QC93/4o, QC139/4p, QC262/4q, QC384/4r and QC155/4t. These were amplified, using RT-PCR, from the sera of patients now residing in Canada, 11 of which were African immigrants. The resulting genomes varied between 9421 and 9475 nt in length and each contains a single ORF of 9018-9069 nt. The sequences showed nucleotide similarities of 77.3-84.3 % in comparison with subtypes 4a (GenBank accession no. Y11604) and 4f (EF589160) and 70.6-72.8 % in comparison with genotype 1 (M62321/1a, M58335/1b, D14853/1c, and 1?/AJ851228) reference sequences. These similarities were often higher than those currently defined by HCV classification criteria for subtype (75.0-80.0 %) and genotype (67.0-70.0 %) division, respectively. Further analyses of the complete and partial E1 and partial NS5B sequences confirmed these 13 'provisionally assigned subtypes'.

Selective and interactive effects of D2 receptor antagonism and positive allosteric mGluR4 modulation on waiting impulsivity.

Science.gov (United States)

Isherwood, Sarah N; Robbins, Trevor W; Nicholson, Janet R; Dalley, Jeffrey W; Pekcec, Anton

2017-09-01

Metabotropic glutamate receptor 4 (mGluR4) and dopamine D 2 receptors are specifically expressed within the indirect pathway neurons of the striato-pallidal-subthalamic pathway. This unique expression profile suggests that mGluR4 and D 2 receptors may play a cooperative role in the regulation and inhibitory control of behaviour. We investigated this possibility by testing the effects of a functionally-characterised positive allosteric mGluR4 modulator, 4-((E)-styryl)-pyrimidin-2-ylamine (Cpd11), both alone and in combination with the D 2 receptor antagonist eticlopride, on two distinct forms of impulsivity. Rats were trained on the five-choice serial reaction time task (5-CSRTT) of sustained visual attention and segregated according to low, mid, and high levels of motor impulsivity (LI, MI and HI, respectively), with unscreened rats used as an additional control group. A separate group of rats was trained on a delay discounting task (DDT) to assess choice impulsivity. Systemic administration of Cpd11 dose-dependently increased motor impulsivity and impaired attentional accuracy on the 5-CSRTT in all groups tested. Eticlopride selectively attenuated the increase in impulsivity induced by Cpd11, but not the accompanying attentional impairment, at doses that had no significant effect on behavioural performance when administered alone. Cpd11 also decreased choice impulsivity on the DDT (i.e. increased preference for the large, delayed reward) and decreased locomotor activity. These findings demonstrate that mGluR4s, in conjunction with D 2 receptors, affect motor- and choice-based measures of impulsivity, and therefore may be novel targets to modulate impulsive behaviour associated with a number of neuropsychiatric syndromes. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

Feasibility study on the application of quality assurance in R and D

Energy Technology Data Exchange (ETDEWEB)

Kwon, Hyuk Il; Yang, Seung Yung; Im, Nam Jin; Cho, Moon Sung; Won, Byung Chool; Yoon, Hyung Moh; Hong, Kyung Sik; Yang, Kwang Suk [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

1994-12-01

Feasibility study for application of quality assurance system was performed as a part of a plan to maximize research productivity and quality. Examples of foreign institutes, such as CRNL, ORNL, BNL, and B and W which obtained good results through application of QA in R and D were studied. As an attempt to improve researcher`s perception of research quality, `Forum for Improvement of Research Quality` and `Seminar on QA in R and D` were held and a survey was performed to investigate researcher`s understanding about QA in R and D. Besides, quality characteristics for each research project were studied and defined to find systematic measures for application of QA in R and D. Basic QA program for R and D (draft) was established and, in 1995, several projects will be selected for model application. Next year, further research on this subject will be performed aiming at the harmonious settlement of QA system in R and D field. 3 figs, 11 tabs, 19 refs. (Author).

Upgrade of The Cyber R and D Platform

Energy Technology Data Exchange (ETDEWEB)

Ko, Chang Seong; Lee, Kyung Jong; Yang, Tae Chun; Kim, Tae Sung; Hong, Hyun Joo [Kyungsung Univ., Seoul (Korea, Republic of)

2007-02-15

Recently, it is necessary to demonstrate the program and experience the safety of radiation disposal by themselves. The objective of this research is to develop a cyber-based performance assessment program for the radiation disposal which is fit for Korean environment. This research covers the following four areas: - Development of Java-based MDPSA pre-processor - Linking MDPSA code to pre and post-processor. - Linking MDPSA code to Cyber R and D platform - Modification of the Cyber R and D platform. The results of this research can be used as a PR database for the central and local government. Using the web-based system, any person or interest group can plug in the system and experience the safety and clarity of the atomic energy and radiation disposal. Also, within the KAERI, research-related knowledge can be stored as a structured format. This enables the sharing, reusability, transparency, reliability and transferability of research results, and promotes the efficiency of research efforts within and outside of research team.

Upgrade of The Cyber R and D Platform

International Nuclear Information System (INIS)

Ko, Chang Seong; Lee, Kyung Jong; Yang, Tae Chun; Kim, Tae Sung; Hong, Hyun Joo

2007-02-01

Recently, it is necessary to demonstrate the program and experience the safety of radiation disposal by themselves. The objective of this research is to develop a cyber-based performance assessment program for the radiation disposal which is fit for Korean environment. This research covers the following four areas: - Development of Java-based MDPSA pre-processor - Linking MDPSA code to pre and post-processor. - Linking MDPSA code to Cyber R and D platform - Modification of the Cyber R and D platform. The results of this research can be used as a PR database for the central and local government. Using the web-based system, any person or interest group can plug in the system and experience the safety and clarity of the atomic energy and radiation disposal. Also, within the KAERI, research-related knowledge can be stored as a structured format. This enables the sharing, reusability, transparency, reliability and transferability of research results, and promotes the efficiency of research efforts within and outside of research team

Fluoride removal from double four-membered ring (D4R) units in As-synthesized Ge-containing zeolites

KAUST Repository

Liu, Xiaolong; Ravon, Ugo; Tuel, Alain

2011-01-01

Fluoride anions can be removed from the framework of as-prepared Ge-containing zeolites ITQ-13 and ITQ-17 without modification of the crystallinity and crystal habit. By contrast to all-silica ITQ-13 for which fluoride could not get out from D4R

R data analysis without programming

CERN Document Server

Gerbing, David W

2013-01-01

This book prepares readers to analyze data and interpret statistical results using R more quickly than other texts. R is a challenging program to learn because code must be created to get started. To alleviate that challenge, Professor Gerbing developed lessR. LessR extensions remove the need to program. By introducing R through less R, readers learn how to organize data for analysis, read the data into R, and produce output without performing numerous functions and programming exercises first. With lessR, readers can select the necessary procedure and change the relevant variables without pro

Cinema 4D R14 cookbook

CERN Document Server

Russell, Simon

2013-01-01

This book is written in a Cookbook style with short recipes designed to effectively teach tools in the minimum amount of time. Each recipe hits on a topic that can be combined or incorporated with other recipes to give you the building blocks you need to start making great designs with Cinema 4D. Rather than demonstrating how to make a few specific and extensive projects, the recipes create a solid base of knowledge to help the reader understand the tools available to foster their own creativity.This book is for professional artists working in architecture, design, production, or games and wan

In-depth analysis on R and D investment and strategy on PV in South Korea

International Nuclear Information System (INIS)

Park, Noeon; Lee, Ki Jong; Lee, Kyong Jae; Lee, Yun Jie; Lee, Kyoungmi; Lee, Sang Hyon

2013-01-01

Photovoltaics (PV) is an eco-friendly and green technology, as a renewable energy source, with the aim of minimizing carbon dioxide emission into the atmosphere. The Korean government has financed various domestic installations as well as research and development (R and D) programs to enter and develop a lead in the worldwide PV market. In this study, R and D investments in the area of PV are analyzed in terms of the respective ministry, performer, research characteristics, PV materials and output levels in detail. The Korean government in the Fiscal year (FY) 2010 provided $178 million dollars from R and D funds for PV development. 74% of the R and D funds in the context of PV has been invested by the Ministry of Knowledge Economy (MKE). Expenditures for R and D programs in terms of PV are mainly funded by small-medium companies (40%), and the portion of the R and D investment in crystalline silicon solar cells is the highest in terms of materials. In spite of the high levels of R and D investment in PV, the output for commercialization was relatively lower compared to the R and D input in FY 2009–2010. With these results, we suggested to develop various solutions to improve the R and D investment efficiency for PV technology in Korea

Handling Uncertainties within R&D Modules of a developing Technology

DEFF Research Database (Denmark)

Pedersen, Jørgen Lindgaard; Perunovic, Zoran

2004-01-01

. Third, the modules that have had always been present in the insulin's R&D, enabled companies to develop mechanism for internal learning and are able to master that part of the process. Finally, in the R&D, outsourcing is related to the whole knowledge acquisition while it seems that minor uncertainties...... and an interview conducted have generated following. First, the further along the process train a module is, it accumulates uncertainties from previous modules. Second, with the growth of complexity, uncertainties grew as well, resulting in the necessity for companies to seek for knowledge on them externally...

The vanishing volume of D = 4 superspace

Energy Technology Data Exchange (ETDEWEB)

Bossard, Guillaume, E-mail: bossard@cpht.polytechnique.f [Ecole Polytechnique (CNRS), Palaiseau Cedex (France). Centre de Physique Theorique; Howe, P.S., E-mail: paul.howe@kcl.ac.u [University of London (United Kingdom). King' s College. Dept. of Mathematics; Stelle, K.S., E-mail: stelle@imperial.ac.u [Imperial College London (United Kingdom). Theoretical Physics Group; Vanhove, Pierre, E-mail: pierre.vanhove@cea.f [University of California, Santa Barbara, CA (United States). Kavli Inst. for Theoretical Physics

2011-07-01

The volume of on-shell D = 4, N = 8 superspace is shown to vanish. Despite this, it is shown that there is a fully supersymmetric and duality-invariant candidate {nabla}{sup 8}R{sup 4} counterterm corresponding to an anticipated seven-loop logarithmic divergence in D = 4. We construct this counterterm explicitly and also give the complete nonlinear extension of the 1=8-BPS {nabla}{sup 6}R{sup 4} invariant. Similar results are derived for N = 4; 5 and 6. (author)

77 FR 47797 - Arkansas: Final Authorization of State Hazardous Waste Management Program Revisions

Science.gov (United States)

2012-08-10

... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 271 [EPA-R06-RCRA-2010-0307; FRL-9713-2] Arkansas: Final Authorization of State Hazardous Waste Management Program Revisions AGENCY: Environmental... authorization of the changes to its hazardous waste program under the Resource Conservation and Recovery Act...

76 FR 19004 - Oklahoma: Final Authorization of State Hazardous Waste Management Program Revisions

Science.gov (United States)

2011-04-06

... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 271 [EPA-R06-RCRA-2010-0307; FRL-9290-9] Oklahoma: Final Authorization of State Hazardous Waste Management Program Revisions AGENCY: Environmental... authorization of the changes to its hazardous waste program under the Resource Conservation and Recovery Act...

78 FR 32223 - Oklahoma: Final Authorization of State Hazardous Waste Management Program Revisions

Science.gov (United States)

2013-05-29

... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 271 [EPA-R06-RCRA-2012-0821; 9817-5] Oklahoma: Final Authorization of State Hazardous Waste Management Program Revisions AGENCY: Environmental Protection Agency (EPA... changes to its hazardous waste program under the Resource Conservation and Recovery Act (RCRA). EPA...

77 FR 38566 - Louisiana: Final Authorization of State Hazardous Waste Management Program Revisions

Science.gov (United States)

2012-06-28

... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 271 [EPA--R06-RCRA-2012-0367; FRL-9692-6] Louisiana: Final Authorization of State Hazardous Waste Management Program Revisions AGENCY: Environmental... authorization of the changes to its hazardous waste program under the Resource Conservation and Recovery Act...

78 FR 54200 - Virginia: Final Authorization of State Hazardous Waste Management Program Revisions

Science.gov (United States)

2013-09-03

... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 271 [EPA-R03-RCRA-2012-0294; FRL-9900-37-Region3] Virginia: Final Authorization of State Hazardous Waste Management Program Revisions AGENCY: Environmental... of revisions to its hazardous waste program under the Resource Conservation and Recovery Act (RCRA...

76 FR 37048 - Louisiana; Final Authorization of State Hazardous Waste Management Program Revisions

Science.gov (United States)

2011-06-24

... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 271 [EPA-R06-RCRA-2010-0307; FRL-9323-8] Louisiana; Final Authorization of State Hazardous Waste Management Program Revisions AGENCY: Environmental... authorization of the changes to its hazardous waste program under the Resource Conservation and Recovery Act...

77 FR 15343 - Oklahoma: Final Authorization of State Hazardous Waste Management Program Revisions

Science.gov (United States)

2012-03-15

... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 271 [EPA-R06-RCRA-2012-0054; FRL-9647-8] Oklahoma: Final Authorization of State Hazardous Waste Management Program Revisions AGENCY: Environmental... authorization of the changes to its hazardous waste program under the Resource Conservation and Recovery Act...

Determinants of Firm R&D

DEFF Research Database (Denmark)

Tingvall, Patrick Gustavsson; Poldahl, Andreas

2012-01-01

Research and Development (R&D) is a key component behind technological development and economic growth; therefore, understanding the drivers of R&D is crucial. An interesting question is the role of technology spillovers, transferred by trade, and their impact on firm R&D. Here we analyze not only...

Economics and the evaluation of publicly funded energy R and D

Energy Technology Data Exchange (ETDEWEB)

Jones, D.W.; Paik, I.K.

1998-10-19

There are three major areas in which economics can contribute to the evaluation of federal R and D: assessment of net benefits, ex ante expected as well as ex post realized; tailoring of R and D portfolios to policy goals; and guiding the contractual organization of R and D production. Additionally, evaluation of R and D and scientific activity tend to be distinctly retrospective, principally because of the long lags between the initial production activity and the observability of consequences. Extending the purview of economic evaluation of R and D, they find ample opportunity for evaluation that can inform current R and D management practice. The conduct of R and D is organized through a series of explicit and implicit contracts designed to elicit long-term commitments by some agents while attempting to limit the commitment by others. It is natural to consider the efficiency with which R and D is conducted as a subject for economic inquiry, although in practice such inquiries generally are restricted to accounting exercises. In evaluating the efficiency with which R and D is done, the current ordinary practice is to look at labor rates and equipment and materials prices while considering quantities of those items as the principal instrument variables in an optimization problem (the authors conceptualization, not that of the typical review of an R and D project). The authors recommend the contractual structure and other elements of the incentive structure (pay and promotion) of R and D production as prime focal points for managerially useful economic evaluation. Non-economic motivations for funding public R and D, including energy R and D, are well known. The US will consider spending several billion dollars on an international space station, partly if not largely, to fund the peaceful employment of scientists from the Former Soviet Union. Nonetheless, it will be useful to understand the economics of the R and D programs even if other considerations play important

Measurement of the {ital D}{sup +}{sub {ital s}}{r_arrow}{eta}l{sup +}{nu} and {ital D}{sup +}{sub {ital s}}{r_arrow}{eta}{prime}l{sup +}{nu} branching ratios

Energy Technology Data Exchange (ETDEWEB)

Brandenburg, G.; Cinabro, D.; Liu, T.; Saulnier, M.; Wilson, R.; Yamamoto, H.; Bergfeld, T.; Eisenstein, B.I.; Ernst, J.; Gladding, G.E.; Gollin, G.D.; Palmer, M.; Selen, M.; Thaler, J.J.; Edwards, K.W.; McLean, K.W.; Ogg, M.; Bellerive, A.; Britton, D.I.; Hyatt, E.R.F.; Janicek, R.; MacFarlane, D.B.; Patel, P.M.; Spaan, B.; Sadoff, A.J.; Ammar, R.; Baringer, P.; Bean, A.; Besson, D.; Coppage, D.; Copty, N.; Davis, R.; Hancock, N.; Kotov, S.; Kravchenko, I.; Kwak, N.; Kubota, Y.; Lattery, M.; Momayezi, M.; Nelson, J.K.; Patton, S.; Poling, R.; Savinov, V.; Schrenk, S.; Wang, R.; Alam, M.S.; Kim, I.J.; Ling, Z.; Mahmood, A.H.; O`Neill, J.J.; Severini, H.; Sun, C.R.; Wappler, F.; Crawford, G.; Duboscq, J.E.; Fulton, R.; Fujino, D.; Gan, K.K.; Honscheid, K.; Kagan, H.; Kass, R.; Lee, J.; Sung, M.; White, C.; Wolf, A.; Zoeller, M.M.; Fu, X.; Nemati, B.; Ross, W.R.; Skubic, P.; Wood, M.; Bishai, M.; Fast, J.; Gerndt, E.; Hinson, J.W.; Miao, T.; Miller, D.H.; Modesitt, M.; Shibata, E.I.; Shipsey, I.P.J.; Wang, P.N.; Gibbons, L.; Johnson, S.D.; Kwon, Y.; Roberts, S.; Thorndike, E.H.; Coan, T.E.; Dominick, J.; Fadeyev, V.; Korolkov, I.; Lambrecht, M.; Sanghera, S.; Shelkov, V.; Skwarnicki, T.; Stroynowski, R.; Volobouev, I.; Wei, G.; Artuso, M.; Gao, M.; Goldberg, M.; He, D.; Horwitz, N.; Kopp, S.; Moneti, G.C.; Mountain, R.; Muheim, F.; Mukhin, Y.; Playfer, S.; Stone, S.; Xing, X.; Bartelt, J.; Csorna, S.E.; Jain, V.; Marka, S.; Gibaut, D.; Kinoshita, K.; Pomianowski, P.; Barish, B.; Chadha, M.; Chan, S.; Cowen, D.F.; Eigen, G.; Miller, J.S.; O`Grady, C.; Urheim, J.; Weinstein, A.J.; Wuerthwein, F.; Asner, D.M.; Athanas, M.; Bliss, D.W.; Brower, W.S.; Masek, G.; Paar, H.P.; Gronberg, J.; Korte, C.M.; Kutschke, R.; Menary, S.; Morrison, R.J.; Nakanishi, S.; Nelson, H.N.; Nelson, T.K.; Qiao, C.; Richman, J.D.; Roberts, D.; Ryd, A.; Tajima, H.; Witherell, M.S.; Balest, R.; Cho, K.; Ford, W.T.; Lohner, M.; Park, H.; Rankin, P.; Smith, J.G.; Alexander, J.P.; (CLEO Collaborat...

1995-11-20

Using the CLEO II detector we measure {ital B}({ital D}{sup +}{sub {ital s}}{r_arrow}{eta}{ital e}{sup +}{nu})/{ital B}({ital D}{sup +}{sub {ital s}}{r_arrow}{phi}{ital e}{sup +}{nu}) =1.24{plus_minus}0.12{plus_minus}0.15, {ital B}({ital D}{sup +}{sub {ital s}}{r_arrow}{eta}{prime}{ital e}{sup +}{nu})/{ital B} ({ital D}{sup +}{sub {ital s}}{r_arrow}{phi}{ital e}{sup +}{nu})=0.43{plus_minus}0.11{plus_minus}0.07, and {ital B}({ital D}{sup +}{sub {ital s}}{r_arrow}{eta}{prime}{ital e}{sup +}{nu})/{ital B} ({ital D}{sup +}{sub {ital s}}{r_arrow}{eta}{ital e}{sup +}{nu})=0.35{plus_minus}0.09{plus_minus}0.07. We find the ratio of vector to pseudoscalar final states, {ital B}{bold (}{ital D}{sup +}{sub {ital s}}{r_arrow}{phi}{ital e}{sup +}{nu})/{ital B} ({ital D}{sup +}{sub {ital s}}{r_arrow}({eta}+{eta}{prime}){ital e}{sup +}{nu}{bold )}=0.60{plus_minus}0.06{plus_minus}0.06, which is similar to the ratio found in nonstrange {ital D} decays. {copyright} {ital 1995} {ital The} {ital American} {ital Physical} {ital Society}.

Optimizing the Level of Renewable Electric R&D Expenditures Using Real Options Analysis

Energy Technology Data Exchange (ETDEWEB)

Davis, G.; Owens, B.

2003-02-01

One of the primary objectives of the United States' federal non-hydro renewable electric R&D program is to promote the development of technologies that have the potential to provide consumers with stable and secure energy supplies. In order to quantify the benefits provided by continued federal renewable electric R&D, this paper uses ''real option'' pricing techniques to estimate the value of renewable electric technologies in the face of uncertain fossil fuel prices. Within the real options analysis framework, the current value of expected future supply from renewable electric technologies, net of federal R&D expenditures, is estimated to be $30.6 billion. Of this value, 86% can be attributed to past federal R&D efforts, and 14% can be attributed to future federal R&D efforts, assuming continued federal R&D funding at $300 million/year. In addition, real options analysis shows that the value of renewable electric technologies increases as current and future R&D funding levels increase. This indicates that the current level of federal renewable electric R&D funding is sub-optimal low.

SuperB R&D computing program: HTTP direct access to distributed resources

Science.gov (United States)

Fella, A.; Bianchi, F.; Ciaschini, V.; Corvo, M.; Delprete, D.; Diacono, D.; Di Simone, A.; Franchini, P.; Donvito, G.; Giacomini, F.; Gianoli, A.; Longo, S.; Luitz, S.; Luppi, E.; Manzali, M.; Pardi, S.; Perez, A.; Rama, M.; Russo, G.; Santeramo, B.; Stroili, R.; Tomassetti, L.

2012-12-01

The SuperB asymmetric energy e+e- collider and detector to be built at the newly founded Nicola Cabibbo Lab will provide a uniquely sensitive probe of New Physics in the flavor sector of the Standard Model. Studying minute effects in the heavy quark and heavy lepton sectors requires a data sample of 75 ab-1 and a luminosity target of 1036cm-2s-1. The increasing network performance also in the Wide Area Network environment and the capability to read data remotely with good efficiency are providing new possibilities and opening new scenarios in the data access field. Subjects like data access and data availability in a distributed environment are key points in the definition of the computing model for an HEP experiment like SuperB. R&D efforts in such a field have been brought on during the last year in order to release the Computing Technical Design Report within 2013. WAN direct access to data has been identified as one of the more interesting viable option; robust and reliable protocols as HTTP/WebDAV and xrootd are the subjects of a specific R&D line in a mid-term scenario. In this work we present the R&D results obtained in the study of new data access technologies for typical HEP use cases, focusing on specific protocols such as HTTP and WebDAV in Wide Area Network scenarios. Reports on efficiency, performance and reliability tests performed in a data analysis context have been described. Future R&D plan includes HTTP and xrootd protocols comparison tests, in terms of performance, efficiency, security and features available.

Oil and Gas R&D Programs

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-03-01

This publication describes the major components of the research and development programs of the Department of Energy`s Office of Natural Gas and Petroleum Technology. These programs are commonly referred to collectively as the `Oil and Gas Program.` This document provides customers with a single source of information describing the details of the individual technology program components. This document reflects the results of a planning cycle that began in early 1996 with the development of a scenario analysis for the programs, followed by the development of the coordinated strategic plan. The technology program plans, which are the most recent products of the planning cycle, expand on the program descriptions presented in the coordinated strategic plan, and represent an initial effort to coordinate the Oil and Gas Program exploration and production programs and budgets. Each technology program plan includes a `roadmap` that summarizes the progress of the program to the present and indicates its future direction. The roadmaps describe the program drivers, vision, mission, strategies, and measures of success. Both the individual technology program plans and the strategic plan are dynamic and are intended to be updated regularly.

Effects of disturbance on ecosystem dynamics of tundra and riparian vegetation: A project in the R4D program. Final report

Energy Technology Data Exchange (ETDEWEB)

Reynolds, J.F.

1995-12-31

Models were proposed as research tools to test the basic understanding of the structure and function of arctic ecosystems, as a means for providing initial management assessments of potential response to energy-related development, and as a vehicle for extrapolation of research results to other arctic sites and landscapes. This final summary report reviews progress made on models at a variety of scales from nutrient uptake by individual roots to nutrient availability within arctic landscapes, and examines potentials and critical limitations of these models for providing insight on patch and landscape level function in tundra regions.

Energy efficiency in the industry: obstacles and R and D needs

International Nuclear Information System (INIS)

Jacquelin, Louis-Marie

2012-05-01

In 2011 ADEME, the French Environment and Energy Management Agency, and TOTAL asked ENEA, a consulting firm specialised in energy and the environment for the industrial sector, to carry out a study. The goal was to update the relevance of their shared program to fund and promote R and D in the Energy Efficiency sector. This survey gathered, in a neutral manner, the opinions of different actors about the need of the industry, the innovation obstacles or the processes of the ADEME TOTAL program. The results of the study have been implemented in the Seventh call for proposal of the program, published at the end of 2011. A report synthesizing the main results of the study has been written to contribute to the promotion of the R and D effort in the Energy Efficiency sector

R.4. Innovative concept for plutonium finishing facility

International Nuclear Information System (INIS)

Bertolotti, G.; Laguerie, I.V. de; Richter, R.; Gillet, B.

1998-01-01

After complete shutdown of the units of the previous UP2 plant, the new R4 facility will ensure the purification of Plutonium of the UP2-800 plant for the whole range of fuel to be reprocessed in the years to come. This facility features four main units: - Purification of plutonium nitrate; - Conversion into plutonium oxide; - PuO 2 conditioning into cans; Acid recovery. An extensive R and D program resulted in significant innovations. From a technological aspect the centrifugal extractor and the sub-critical tube bundle tank contributed to the reduction of the building dimensions. The extensive use of on-line analyses enables a more efficient follow-up of the process while minimizing the effluent production. On the other hand, the organization of the building which consists in grouping the rooms presenting the same risk of dispersal of nuclear materials also contributed to reduce the active zone volume. This facility, as any other facilities on the LA HAGUE site, will be remotely operated. (author)

Safety management of a complex R&D ground operating system

Science.gov (United States)

Connors, J.; Mauer, R. A.

1975-01-01

Report discusses safety program implementation for large R&D operating system. Analytical techniques are defined and suggested as tools for identifying potential hazards and determining means to effectively control or eliminate hazards.

Prospects for Russian Military R&D.

Science.gov (United States)

1996-01-01

conflicts with a self-defeating desire to close the West out, fueled by nationalistic re- sentment of Russia’s underdog position and a distinctly Cold War...increasingly inte- grated. Until Russia succeeds in creating its brand of market econ- omy and achieves widespread economic prosperity, a process that could...defense spending in 1996 would focus on " brand new weapons and equipment" and that spending for defense R&D programs would remain at this year’s

R&D program benefits estimation: DOE Office of Electricity Delivery and Energy Reliability

Energy Technology Data Exchange (ETDEWEB)

None, None

2006-12-04

The overall mission of the U.S. Department of Energy’s Office of Electricity Delivery and Energy Reliability (OE) is to lead national efforts to modernize the electric grid, enhance the security and reliability of the energy infrastructure, and facilitate recovery from disruptions to the energy supply. In support of this mission, OE conducts a portfolio of research and development (R&D) activities to advance technologies to enhance electric power delivery. Multiple benefits are anticipated to result from the deployment of these technologies, including higher quality and more reliable power, energy savings, and lower cost electricity. In addition, OE engages State and local government decision-makers and the private sector to address issues related to the reliability and security of the grid, including responding to national emergencies that affect energy delivery. The OE R&D activities are comprised of four R&D lines: High Temperature Superconductivity (HTS), Visualization and Controls (V&C), Energy Storage and Power Electronics (ES&PE), and Distributed Systems Integration (DSI).

Federal role in resource recovery will focus on waste-to-energy R and D

Energy Technology Data Exchange (ETDEWEB)

Dawson, R.A.

1981-05-01

Virtually all of the federal programs created in recent years to sponsor resource recovery R and D have been slated for budget cuts or termination by the administration of President Ronald Reagan. The only programs that will survive revised fiscal budgets will be waste-to-energy R and D studies sponsored by DOE and EPA. Differing reactions to such cuts are apparent: the affected agencies are protesting, while private industry welcomes this hands-off policy.

Guide on Project Web Access of SFR R and D and Technology Monitoring System

International Nuclear Information System (INIS)

Lee, Dong Uk; Won, Byung Chool; Lee, Yong Bum; Kim, Young In; Hahn, Do Hee

2008-09-01

The SFR R and D and technology monitoring system based on the MS enterprise project management is developed for systematic effective management of 'Development of Basic Key Technologies for Gen IV SFR' project which was performed under the Mid- and Long-term Nuclear R and D Program sponsored by the Ministry of Education, Science and Technology. This system is a tool for project management based on web access. Therefore this manual is a detailed guide for Project Web Access(PWA). Section 1 describes the common guide for using of system functions such as project server 2007 client connection setting, additional outlook function setting etc. The section 2 describes the guide for system administrator. It is described the guide for project management in section 3, 4

Guide on Project Web Access of SFR R and D and Technology Monitoring System

Energy Technology Data Exchange (ETDEWEB)

Lee, Dong Uk; Won, Byung Chool; Lee, Yong Bum; Kim, Young In; Hahn, Do Hee

2008-09-15

The SFR R and D and technology monitoring system based on the MS enterprise project management is developed for systematic effective management of 'Development of Basic Key Technologies for Gen IV SFR' project which was performed under the Mid- and Long-term Nuclear R and D Program sponsored by the Ministry of Education, Science and Technology. This system is a tool for project management based on web access. Therefore this manual is a detailed guide for Project Web Access(PWA). Section 1 describes the common guide for using of system functions such as project server 2007 client connection setting, additional outlook function setting etc. The section 2 describes the guide for system administrator. It is described the guide for project management in section 3, 4.

R object-oriented programming

CERN Document Server

Black, Kelly

2014-01-01

This book is designed for people with some experience in basic programming practices. It is also assumed that they have some basic experience using R and are familiar using the command line in an R environment. Our primary goal is to raise a beginner to a more advanced level to make him/her more comfortable creating programs and extending R to solve common problems.

Motors of Change for R&D and Innovation towards Sustainable Energy in Turkey

Directory of Open Access Journals (Sweden)

Şiir Kılkış

2014-04-01

Full Text Available There is a revival of mission-oriented R&D and innovation programs in prioritized areas that serve the aim of decoupling economic growth from environmental pressures. This paper analyzes the governance process in activating the innovation actors in the area of energy technologies in Turkey. This process that was coordinated by TÜBİTAK led to the National Energy R&D and Innovation Strategy for 2011-2016. The three main phases of this process are mapped to be strategy-building, prioritization, and implementation involving six different participatory approaches. The Strategy is based on the strategic aims of mission-oriented R&D projects, capacity advancement, commercialization, and governance. Two new, call-based grant programs launched with eleven energy calls in the first year are overviewed. These programs were key to activating a phase known as “motors of change” for the innovation system. The second year led to the selection of the topic of “Energy Efficiency” for a pilot technology roadmap process, which involved a separate, multi-actor governance process. The paper concludes with the key role of R&D and innovation in allowing energy to contribute to the sustainable development of Turkey by utilizing energy resources effectively and efficiently.

Status and Update of the RaDIATE Collaboration R&D Program

Energy Technology Data Exchange (ETDEWEB)

Ammigan, K. [Fermilab; Hurh, P. [Fermilab

2017-07-01

The Radiation Damage In Accelerator Target Environments (RaDIATE) collaboration was founded in 2012 and currently consists of over 50 participants and 11 institutions globally. Due to the increasing power of future proton accelerator sources in target facilities, there is a critical need to further understand the physical and thermo-mechanical radiation response of target facility materials. Thus, the primary objective of the RaDIATE collaboration is to draw on existing expertise in the nuclear materials and accelerator targets fields to generate new and useful materials data for application within the accelerator and fission/fusion communities. Current research activities of the collaboration include post irradiation examination (PIE) of decommissioned components from existing beamlines such as the NuMI beryllium beam window and graphite NT-02 target material. PIE of these components includes advanced microstructural analyses (SEM/TEM, EBSD, EDS) and micro-mechanics technique such as nano-indentation, to help characterize any microstructural radiation damage incurred during operation. New irradiation campaigns of various candidate materials at both low and high energy beam facilities are also being pursued. Beryllium helium implantation studies at the University of Surrey as well as high energy proton irradiation of various materials at Brookhaven National Laboratory’s BLIP facility have been initiated. The program also extends to beam-induced thermal shock experiments using high intensity beam pulses at CERN’s HiRadMat facility, followed by advanced PIE activities to evaluate thermal shock resistance of the materials. Preliminary results from ongoing research activities, as well as the future plans of the RaDIATE collaboration R&D program will be discussed.

The Progress of SBIR Supported R and D of Solid State Pulse Modulators

International Nuclear Information System (INIS)

Koontz, R

2004-01-01

The Small Business Innovative Research (SBIR) grant program funded by the US Department of Energy makes a number of awards each year for R and D in the field of accelerator technology including high power pulse modulators and their components. This paper outlines program requirements, and reviews some of the awards made in the last three years in support of high power modulator systems and solid state switching. A number of award recipients are presenting the results of their SBIR R and D at this workshop

ATLAS Cloud R&D

CERN Document Server

Panitkin, S; The ATLAS collaboration; Caballero Bejar, J; Benjamin, D; DiGirolamo, A; Gable, I; Hendrix, V; Hover, J; Kucharczuk, K; Medrano LLamas, R; Love, P; Ohman, H; Paterson, M; Sobie, R; Taylor, R; Walker, R; Zaytsev, A

2014-01-01

The computing model of the ATLAS experiment was designed around the concept of grid computing and, since the start of data taking, this model has proven very successful. However, new cloud computing technologies bring attractive features to improve the operations and elasticity of scientific distributed computing. ATLAS sees grid and cloud computing as complementary technologies that will coexist at different levels of resource abstraction, and two years ago created an R&D working group to investigate the different integration scenarios. The ATLAS Cloud Computing R&D has been able to demonstrate the feasibility of offloading work from grid to cloud sites and, as of today, is able to integrate transparently various cloud resources into the PanDA workload management system. The ATLAS Cloud Computing R&D is operating various PanDA queues on private and public resources and has provided several hundred thousand CPU days to the experiment. As a result, the ATLAS Cloud Computing R&D group has gained...

Posttreatment with group II metabotropic glutamate receptor agonist 2R,4R-4-aminopyrrolidine-2,4-dicarboxylate is only weakly effective on seizures in immature rats

Czech Academy of Sciences Publication Activity Database

Folbergrová, Jaroslava; Druga, Rastislav; Tsenov, Grygoriy; Haugvicová, Renata; Otáhal, Jakub

2009-01-01

Roč. 1273, - (2009), s. 144-154 ISSN 0006-8993 R&D Projects: GA ČR(CZ) GA309/05/2015; GA ČR GA309/08/0292; GA ČR(CZ) GA304/07/1137 Institutional research plan: CEZ:AV0Z50110509; CEZ:AV0Z50200510 Keywords : DL-homocysteic acid-induced seizures * posttreatment with 2R * 4R-APDC * partial protection Subject RIV: FH - Neuro logy Impact factor: 2.463, year: 2009

77 FR 76414 - William D. Ford Federal Direct Loan Program

Science.gov (United States)

2012-12-28

... Federal Direct Loan Program AGENCY: Department of Education. ACTION: Final regulations; correction... Loan (Perkins Loan) Program; the Federal Family Education Loan (FFEL) Program; and the William D. Ford Federal Direct Loan (Direct Loan) Program, including the Public Service Loan Forgiveness (PSLF) Program...

4D Joint Stratigraphic Inversion of Prestack Seismic Data: Application to the CO2 Storage Reservoir (Utsira Sand Formation at Sleipner Site Inversion stratigraphique jointe 4D de données sismiques avant sommation : application au réservoir de stockage de CO2 (Formation Utsira du site de Sleipner

Directory of Open Access Journals (Sweden)

Labat K.

2012-04-01

Full Text Available Seismic monitoring is commonly used in the oil industry to follow the evolution of reservoir properties during production. We present a methodology of time-lapse (or 4D stratigraphic inversion, which is able to provide an estimation of P- and S-wave impedance variations in the reservoir by inverting prestack time-lapse seismic data. The 4D inversion is implemented in the time domain and requires a time scaling law for each repeated seismic dataset in order to adjust the arrival times of homologous events observed in the so-called reference and monitor datasets. This operation is often referred to as the warping problem. The 4D inversion is a 3-step methodology. The first step consists in inverting each seismic vintage independently, thus providing as many P- and S-wave impedance distributions as datasets considered. The second step uses the available P-wave impedance information to solve the warping problem which is crucial to the third and final step: the joint inversion of all available seismic vintages. This 4D inversion sequence was applied to seismic datasets recorded on the Norwegian CO2 storage reservoir of Sleipner field located in the North Sea. The latter is becoming a reference industrial site for the long-term storage of carbon dioxide (CO2 in a saline aquifer, the Utsira sand formation. We focused our 4D inversion study on the 1994 and 2006 vintages acquired two years before and ten years after the beginning of CO2 injection, respectively. The warping correction resulted in a time-scaling law with a maximum pushdown effect of about 45 ms at the base of the Utsira aquifer. The joint 4D inversion results show more consistency than the single 3D inversion results: the 4D inversion notably provides P-wave impedances for the CO2 -saturated sandstones which are close to the values derived from rock physics studies. Le monitoring sismique est couramment utilisé dans l'industrie pétrolière pour suivre l'évolution des propriétés des r

Bacillus cereus Fnr binds a [4Fe-4S] cluster and forms a ternary complex with ResD and PlcR

Directory of Open Access Journals (Sweden)

Esbelin Julia

2012-06-01

Full Text Available Abstract Background Bacillus cereus is a facultative anaerobe that causes diarrheal disease in humans. Diarrheal syndrome may result from the secretion of various virulence factors including hemolysin BL and nonhemolytic enterotoxin Nhe. Expression of genes encoding Hbl and Nhe is regulated by the two redox systems, ResDE and Fnr, and the virulence regulator PlcR. B. cereus Fnr is a member of the Crp/Fnr family of iron-sulfur (Fe-S proteins. Only its apo-form has so far been studied. A major goal in deciphering the Fnr-dependent regulation of enterotoxin genes is thus to obtain and characterize holoFnr. Results Fnr has been subjected to in vitro Fe-S cluster reconstitution under anoxic conditions. UV-visible and EPR spectroscopic analyses together with the chemical estimation of the iron content indicated that Fnr binds one [4Fe-4S]2+ cluster per monomer. Atmospheric O2 causes disassembly of the Fe-S cluster, which exhibited a half-life of 15 min in air. Holo- and apoFnr have similar affinities for the nhe and hbl promoter regions, while holoFnr has a higher affinity for fnr promoter region than apoFnr. Both the apo- and holo-form of Fnr interact with ResD and PlcR to form a ternary complex. Conclusions Overall, this work shows that incorporation of the [4Fe-4S]2+ cluster is not required for DNA binding of Fnr to promoter regions of hbl and nhe enterotoxin genes or for the formation of a ternary complex with ResD and PlcR. This points to some new unusual properties of Fnr that may have physiological relevance in the redox regulation of enterotoxin gene regulation.

Fiscal 1998 research report. Survey on the current trend of private R and D efforts; 1998 nendo chosa hokokusho. Minkan no kenkyu kaihatsu doko no jittai ni kansuru chosa

Energy Technology Data Exchange (ETDEWEB)

NONE

1999-03-01

For promotion of the R and D system of technologies creating new industries, this survey collected the basic data and information on the trend of private R and D efforts and industries, and arranged every data and information obtained. The data on United States, Germany, France and U.K. in addition to Japan were collected. Survey was made first on the administrative support system for private R and D efforts. The R and D-related budget, R and D support program and private R and D-related fund of Japan, United States and U.K. are mainly outlined. Survey was made next on private R and D activities. The R and D-related fund, researcher and patent of main countries are outlined in international comparison. Survey was also made on the current state of various industries. The industry scale and structure of every Japanese manufacturing industry are outlined. Finally, the industrial statistics are given concerning Japanese 'chemical industry,' 'communication-electronics-electric measuring instrument industry' and 'automobile industry' with a high rate of R and D-related expenditures. (NEDO)

Selection methodology for LWR safety R and D programs and proposals. Volume III. User's manual for the multi-attribute utility package (MAUP)

International Nuclear Information System (INIS)

Hale, M.; Turnage, J.J.; Husseiny, A.A.; Ritzman, R.L.

1981-02-01

The computer program which was developed to apply the multi-attribute utility (MAU) methodology to the selection of LWR safety R and D programs and proposals is described. An overview of the MAU method is presented, followed by a description of the steps incorporated in developing individual modules for use in the multi-attribute utility package (MAUP). Each module is described complete with usage information and an example of computer output

FY2014 Energy Storage R&D Annual Progress Report

Energy Technology Data Exchange (ETDEWEB)

none,

2015-03-01

The Energy Storage research and development (R&D) subprogram within the DOE Vehicle Technologies Office (VTO) provides support and guidance for projects focusing on batteries for plug-in electric vehicles. Program targets focus on overcoming technical barriers to enable market success including: (1) significantly reducing battery cost, (2) increasing battery performance (power, energy, durability), (3) reducing battery weight & volume, and (4) increasing battery tolerance to abusive conditions such as short circuit, overcharge, and crush. This report describes the progress made on the research and development projects funded by the Energy Storage subprogram in 2014. You can download individual sections at the following website, http://energy.gov/eere/vehicles/downloads/vehicle-technologies-office-2014-energy-storage-rd-annual-report.

CHOICE Internal report I-4: The current status of ICT R&D&I for Chinese Eco-Cities

OpenAIRE

Owens, TJ; Itagaki, T

2015-01-01

This report attempts to give a flavour of the current of status of ICT R&D&I for Chinese Eco-cities and thereby provide some insights into the potential of China’s emerging market for Eco-city solutions for EU- China collaborative ICT R&D&I. It addresses Eco-city standards development in China. Evaluation Centres for Eco-City software solutions, the context into which ICT for Chinese Eco-cities fits, Chinese ICT R&D in smart cities, EU-China collaboration in ICT R&D smart cities, EU Member st...

78 FR 24985 - Amendment of Restricted Areas R-6703A, B, C, D; and Establishment of Restricted Areas R-6703E, F...

Science.gov (United States)

2013-04-29

...-0371; Airspace Docket No. 12-ANM-14] RIN 2120-AA66 Amendment of Restricted Areas R-6703A, B, C, D; and Establishment of Restricted Areas R-6703E, F, G, H, I, and J; WA AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action modifies the internal boundaries of R-6703 by further...

AN EXCEL-BASED DECISION SUPPORT SYSTEM FOR SCORING AND RANKING PROPOSED R&D PROJECTS

OpenAIRE

ANNE DE PIANTE HENRIKSEN; SUSAN W. PALOCSAY

2008-01-01

One of the most challenging aspects of technology management is the selection of research and development (R&D) projects from among a group of proposals. This paper introduces an interactive, user-friendly decision support system for evaluating and ranking R&D projects and demonstrates its application on an example R&D program. It employs the scoring methodology developed by Henriksen and Traynor to provide a practical technique that considers both project merit and project cost in the evalua...

Windows and Envelope R&D Opportunities Workshop

Energy Technology Data Exchange (ETDEWEB)

Building Technologies Office

2018-02-01

BTO's Emerging Technologies program held a two-day workshop on “Windows and Envelope R&D Opportunities” on May 31 and June 1, 2017 at the Illinois Institute of Technology in Chicago, Illinois. A broad range of about 100 experts from industry, academia, national laboratories, and government participated, contributing their ideas, insights, and perspectives. Their feedback is intended to help inform and augment BTO’s research and development activities.

IEA Hydrogen Implementing Agreement's Second Generation R and D and the Hydrogen Economy

Energy Technology Data Exchange (ETDEWEB)

Beck, N.; Garcia-Conde, A. G.; Riis, T. U.; Luzzi, A.; Valladares, M. R. de

2005-07-01

Since its creation by the International Energy Agency in the late 1970's, the IEA Hydrogen Implementing Agreement (HIA) has been at the forefront of collaborative international hydrogen research and development (R and D) (http://www.ieahia.org. ) The collective body of HIA hydrogen R and D will contribute to definition of the hydrogen economy. The five-year [2004-2009) mission of the IEA HIA is to advance the adoption of a Hydrogen Economy through strategic implementation of collaborative R and D and outreach programs that address key issues and barriers. The three goals for the Second Generation HIA are: Advancement of science and technology via pre-commercial collaborative RD and D programs; Assessment of market environment, including the non-energy sector; and Implementation of outreach program, aimed at community acceptance and support. The HIA launched its Second Generation of hydrogen R and D in the latter part of 2004. The HIA's anniversary report: In Pursuit of the Future: 25 Years of IEA Research towards the realization of Hydrogen Energy Systems (http://ieahia.org/pdfs/IEA_AnniversaryReport_HIA.pdf) chronicles its contributions to hydrogen R and D. As the hydrogen economy takes shape, the HIA is pleased to share highlights of its R and D history together with progress on planned activities and its six current annexes, listed below: Task 15 Photobiological Production of Hydrogen Task 16 Hydrogen from Carbon-Containing Materials Task 17 Solid and Liquid Storage Task 18 Integrated Systems Evaluation Task 19 Safety Task 20 Hydrogen from Waterphotolysis Planned successor annexes in storage and photobiological hydrogen production will also be discussed, along with a task on high temperature hydrogen production that is now in the definition phase. Over 250 experts from the sixteen member HIA countries and the European Union contribute to this portfolio of cutting edge hydrogen R and D and analysis activities. Several other countries are expected to

Neutrino Factory R and D in the U.S

International Nuclear Information System (INIS)

Zisman, Michael S.

2003-01-01

We report here on the technical progress and R andD plans of the U.S. Neutrino Factory and Muon Collider Collaboration. Programs in targetry, cooling, acceleration, and simulations are covered. U.S. activities in support of the international Muon Ionization Cooling Experiment (MICE) are also described

Using iPods[R] and iPads[R] in Teaching Programs for Individuals with Developmental Disabilities: A Systematic Review

Science.gov (United States)

Kagohara, Debora M.; van der Meer, Larah; Ramdoss, Sathiyaprakash; O'Reilly, Mark F.; Lancioni, Giulio E.; Davis, Tonya N.; Rispoli, Mandy; Lang, Russell; Marschik, Peter B.; Sutherland, Dean; Green, Vanessa A.; Sigafoos, Jeff

2013-01-01

We conducted a systematic review of studies that involved iPods[R], iPads[R], and related devices (e.g., iPhones[R]) in teaching programs for individuals with developmental disabilities. The search yielded 15 studies covering five domains: (a) academic, (b) communication, (c) employment, (d) leisure, and (e) transitioning across school settings.…

The ARCHER project (Advanced High-Temperature Reactors for Cogeneration of Heat and Electricity R&D)

Energy Technology Data Exchange (ETDEWEB)

Knol, S., E-mail: knol@nrg.eu [Nuclear Research and consultancy Group (NRG), PO Box 25, NL-1755 ZG Petten (Netherlands); Fütterer, M.A. [Joint Research Centre, Institute for Energy, Petten (Netherlands); Roelofs, F. [Nuclear Research and consultancy Group (NRG), PO Box 25, NL-1755 ZG Petten (Netherlands); Kohtz, N. [TÜV Rheinland, Köln (Germany); Laurie, M. [Joint Research Centre, Institute for Transuranium elements, Karlsruhe (Germany); Buckthorpe, D. [UMAN, University of Manchester, Manchester (United Kingdom); Scheuermann, W. [IKE, Stuttgart University, Stuttgart (Germany)

2016-09-15

The European HTR R&D project ARCHER (Advanced High-Temperature Reactors for Cogeneration of Heat and Electricity R&D) builds on a solid HTR technology foundation in Europe, established through former national UK and German HTR programs and in European framework programs. ARCHER runs from 2011 to 2015 and targets selected HTR R&D subjects that would specifically support demonstration, with a focus on experimental effort. In line with the R&D and deployment strategy of the European Sustainable Nuclear Energy Technology Platform (SNETP) ARCHER contributes to maintaining, strengthening and expanding the HTR knowledge base in Europe to lay the foundations for demonstration of nuclear cogeneration with HTR systems. The project consortium encompasses conventional and nuclear industry, utilities, Technical Support Organizations, R&D organizations and academia. ARCHER shares results with international partners in the Generation IV International Forum and collaborates directly with related projects in the US, China, Japan, the Republic of Korea and South Africa. The ARCHER project has finished, and the paper comprises an overview of the achievements of the project.

The Development of Productivity Practical Management Model at Automotive Mechanical Technology Skill Program in Semarang Vocational Schools, Indonesia

Science.gov (United States)

Hadromi; Rachman, Maman; Soesanto; Kartana, Tri Jaka

2015-01-01

The purpose of this research is to develop automotive Mechanical Technology Skill Program (TMO) in Vocational School. The Research and Development (R&D) object was done in SMK 1, 4 and 7 Semarang, Indonesia. The result was achieved productivity Practical Management Final Model at TMO skill Program in Vocational school named momanticproter.…

Radiosynthesis of 3-{l_brace}[4-(4-[{sup 18}F]fluorobenzyl)]piperazin-1-yl{r_brace}methyl-1H-pyrrolo[2,3-b]pyridine: A potential dopamine D{sub 4} receptor imaging agent

Energy Technology Data Exchange (ETDEWEB)

Haibin Tian; Duanzhi Yin; Junling Li; Lan Zhang; Cunfu Zhang; Yongxian Wang; Wei Zhou [Radiopharmaceutical Research Center, Shanghai Inst. of Nuclear Research, The Chinese Academy of Sciences, Shanghai, SH (China)

2003-07-01

The dopamine D{sub 4} receptor (D{sub 4}R) is expressed in low density in various extrastriatal brain regions. This receptor subtype is discussed in relation to the pathophysiology and treatment of schizophrenia but to date no selective positron emission tomography (PET) ligand is available to study its distribution in vivo. The 7-azaindole derivative 3-([4-(4-iodophenyl)piperazin-1-yl]-methyl)-1H-pyrrolo [2,3-b]pyridine (L-750,667) is a novel, high-affinity (K{sub i}=0.51nM) and selective D{sub 4}R ligand. L-750,667 analogue 3-[4-(4-[{sup 18}F]fluorobenzyl)]piperazin-1-yl methyl-1H-pyrrolo[2,3-b]-pyridine was prepared by reacting 3-(piperazin-1-yl)-methyl-1H-pyrrolo[2,3-b]pyridine with 4-[ 18F]fluorobenzaldehyde, which was labeled with no carrier added [ 18F]fluoride. The radiochemical yield of 3-[4-(4-[{sup 18}F]fluorobenzyl)]piperazin-1-yl methyl-1H-pyrrolo[2,3-b]pyridine was 12.0% at end of synthesis (EOS), and the synthesis time was 73min. The labeled benzaldehydes may be useful precursors for the radiosyntheses of other complex radiotracers for PET.

R&D ERL: Beam dynamics, parameters, and physics to be learned

Energy Technology Data Exchange (ETDEWEB)

Kayran, D.

2010-02-01

The R&D ERL facility at BNL aims to demonstrate CW operation of ERL with average beam current in the range of 0.1-1 ampere, combined with very high efficiency of energy recovery. The ERL is being installed in one of the spacious bays in Bldg. 912 of the RHIC/AGS complex (Fig. 1). The bay is equipped with an overhead crane. The facility has a control room, two service rooms and a shielded ERL cave. The control room is located outside of the bay in a separate building. The single story house is used for a high voltage power supply for 1 MW klystron. The two-story unit houses a laser room, the CW 1 MW klystron with its accessories, most of the power supplies and electronics. The ERL R&D program has been started by the Collider Accelerator Department (C-AD) at BNL as an important stepping-stone for 10-fold increase of the luminosity of the Relativistic Heavy Ion Collider (RHIC) using relativistic electron cooling of gold ion beams with energy of 100 GeV per nucleon. Furthermore, the ERL R&D program extends toward a possibility of using 10-20 GeV ERL for future electron-hadron/heavy ion collider, MeRHIC/eRHIC. These projects are the driving force behind the development of ampere-class ERL technology, which will find many applications including light sources and FELs. The intensive R&D program geared towards the construction of the prototype ERL is under way: from development of high efficiency photo-cathodes to the development of new merging system compatible with emittance compensation.

miR-21 promotes fibrogenic epithelial-to-mesenchymal transition of epicardial mesothelial cells involving Programmed Cell Death 4 and Sprouty-1

DEFF Research Database (Denmark)

Brønnum, Hasse; Andersen, Ditte C; Schneider, Mikael

2013-01-01

and miR-21-dependent targeting of Programmed Cell Death 4 (PDCD4) and Sprouty Homolog 1 (SPRY1) significantly contributed to the development of a fibroblastoid phenotype. However, PDCD4- and SPRY1-targeting was not entirely ascribable to all phenotypic effects from miR-21, underscoring the pleiotropic......, especially TGF-β, promoted EMT progression in EMC cultures, which resulted in differential expression of numerous miRNAs, especially the pleiotropic miR-21. Accordingly, ectopic expression of miR-21 substantially promoted the fibroblast-like phenotype arising from fibrogenic EMT, whereas an antagonist...... that targeted miR-21 blocked this effect, as assessed on the E-cadherin/α-smooth muscle actin balance, cell viability, matrix activity, and cell motility, thus making miR-21 a relevant target of EMC-derived fibrosis. Several mRNA targets of miR-21 was differentially regulated during fibrogenic EMT of EMCs...

Differentiation of Forebrain and Hippocampal Dopamine 1-Class Receptors, D1R and D5R, in Spatial Learning and Memory

Science.gov (United States)

Sariñana, Joshua; Tonegawa, Susumu

2017-01-01

Activation of prefrontal cortical (PFC), striatal, and hippocampal dopamine 1-class receptors (D1R and D5R) is necessary for normal spatial information processing. Yet the precise role of the D1R versus the D5R in the aforementioned structures, and their specific contribution to the water-maze spatial learning task remains unknown. D1R- and D5R- specific in situ hybridization probes showed that forebrain restricted D1R and D5R KO mice (F-D1R/D5R KO) displayed D1R mRNA deletion in the medial (m)PFC, dorsal and ventral striatum, and the dentate gyrus (DG) of the hippocampus. D5R mRNA deletion was limited to the mPFC, the CA1 and DG hippocampal subregions. F-D1R/D5R KO mice were given water-maze training and displayed subtle spatial latency differences between genotypes and spatial memory deficits during both regular and reversal training. To differentiate forebrain D1R from D5R activation, forebrain restricted D1R KO (F-D1R KO) and D5R KO (F-D5R KO) mice were trained on the water-maze task. F-D1R KO animals exhibited escape latency deficits throughout regular and reversal training as well as spatial memory deficits during reversal training. F-D1R KO mice also showed perseverative behavior during the reversal spatial memory probe test. In contrast, F-D5R KO animals did not present observable deficits on the water-maze task. Because F-D1R KO mice showed water-maze deficits we tested the necessity of hippocampal D1R activation for spatial learning and memory. We trained DG restricted D1R KO (DG-D1R KO) mice on the water-maze task. DG-D1R KO mice did not present detectable spatial memory deficit, but did show subtle deficits during specific days of training. Our data provides evidence that forebrain D5R activation plays a unique role in spatial learning and memory in conjunction with D1R activation. Moreover, these data suggest that mPFC and striatal, but not DG D1R activation are essential for spatial learning and memory. PMID:26174222

78 FR 15338 - New York: Final Authorization of State Hazardous Waste Management Program Revisions

Science.gov (United States)

2013-03-11

... authorization of changes to its hazardous waste program under the Solid Waste Disposal Act, as amended, commonly... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 271 [EPA-R02-RCRA-2013-0144; FRL-9693-3] New York: Final Authorization of State Hazardous Waste Management Program Revisions AGENCY: Environmental...

R

Directory of Open Access Journals (Sweden)

Prokop Jacek

2015-06-01

Full Text Available This paper analyzes the impact of R&D activities in an oligopoly on consumer surplus and social welfare. We use a two-stage model to analyze the behavior of duopolists at the research level, and in the final-product market, under the assumption of linear and quadratic cost functions. Three options for firm competition are considered: 1 Cournot competition at both stages; 2 cooperation at the R&D stage and Cournot competition in the final-product market; and 3 cooperation at both stages. Numerical simulations for various levels of R&D spillovers are conducted to analyze the welfare effects of firm decisions. We conclude that for high levels of technological spillovers, total welfare is highest when firms engage in cooperation at the R&D stage, and compete in the final product market, independent of the shape of cost functions. However, the functional form of production costs has a qualitative impact on welfare when firms fully compete.

Petroleum R and D collaboration

International Nuclear Information System (INIS)

Kerr, R.

1995-01-01

Conditions for collaboration in research and development (R and D) were developed based on a decision-tree analysis. A key requirement for effective R and D collaboration was stated to be the company's ability to internalize a significant portion of the benefits. This was seen as the principal factor that determined good collaborators and good industries for collaboration. It was noted that collaboration benefits can also be improved through R and D exchanges in collaborative associations. Simple decision-tree analysis tended to understate the advantages of collaboration. Portfolio risk reduction and inter-project synergies were significant additional advantages. Collaborative R and D was said to be the preferred route for the development of a broad base of petroleum-related technologies. 5 tabs., 2 figs

Synthesis of (3R)-3-(4-fluorophenylsulfonamido)-1,2,3,4-tetra-hydro-9-[4-3H] carbazolepropanoic acid

International Nuclear Information System (INIS)

Pleiss, Ulrich; Radtke, Martin; Schmitt, Peter

1990-01-01

(3R)-3-(4-Fluorophenylsulfonamido)-1,2,3,4-tetrahydro-9-[4- 3 H]carbazolepropanoic acid ( [ 3 H]BAY u 3405) (5) was synthesized by catalytic reduction of (3R)-3-(4-fluorophenylsulfonamido)-4-oxo-1,2,3,4-tetrahydro-9-carbazolepropanoic acid (4) with tritium. The precursor (4) was prepared by esterification and following oxidation of BAY u 3405 with 2,3-dichloro-5,6-dicyano-p-benzoquinone. 3 H NMR analysis of the final product showed the formation of [4α- 3 H]BAY us 3405 and [4β- 3 H]BAY u 3405 in a ratio of 1:1. (author)

76 FR 18624 - Research, Technical Assistance and Training Programs: Notice of Final Circular

Science.gov (United States)

2011-04-04

... to FTA Circular 6100.1D, Research and Technical Assistance Training Program: Application Instructions... DEPARTMENT OF TRANSPORTATION Federal Transit Administration Research, Technical Assistance and Training Programs: Notice of Final Circular AGENCY: Federal Transit Administration (FTA), DOT. ACTION...

Development Plan and R and D Status of China Lead-based Reactor

Energy Technology Data Exchange (ETDEWEB)

Wu, Yican; Bai, Yunqing; Song, Yong; Li, Yazhou; Team, FDS [Institute of Nuclear Energy Safety Technology, Beijing (Switzerland)

2013-07-01

Chinese Academy of Sciences (CAS) launched an engineering project to develop ADS system and lead-based reactors named China LEAd-based Reactor (CLEAR) series. The Institute of Nuclear Energy Safety Technology (INEST) will be responsible for the CLEAR design and R and D. In this project, CAS plans to develop the lead-based reactors through 3 phases which are 10MWth lead based research reactor (CLEAR-I), 100MWth lead-based experimental reactor (CLEAR-II), 1000MWth lead-based demonstration reactor (CLEAR-III). As a pre-testing facility, a lead-based zero-power reactor (CLEAR-0) is required to be built before CLEAR-I construction and operation. The new conceptual design of lead-based reactors, including hydrogen production, tritium production for fusion energy and thorium utilization, is also on-going. Lead-lithium cooled fusion reactor blanket design and lead-lithium experimental loops have been developed more than 10 years. CLEAR series reactor conceptual design has been finished and detailed engineering design for CLEAR-I is underway. The R and D activities for CLEAR reactor including design and safety software, key components, structural materials, lead-based experimental loops and neutronics experimental platform are developing. Series of liquid lead-based experimental loops named DRAGON (Lead-Lithium) and KYLIN (Lead-Bismuth) have already been built or on constructing to performed experiments investigating the structure material corrosion issues and the thermal-hydraulic properties of lead-based coolant. The Highly Intensified D-T Neutron Generator HINEG for neutron experiment and software validation will be constructed. Series advanced reactor design software and nuclear library have been developed for lead-alloy cooled reactor, including CAD based Multi-Functional 4D Neutronics Simulation System (Visual Bus), Monte Carlo Automatic Modeling Program for Radiation Transport Simulation (MCAM), Super Monte Carlo Simulation Program (SuperMC), Nuclear Radiation

Development Plan and R and D Status of China Lead-based Reactor

International Nuclear Information System (INIS)

Wu, Yican; Bai, Yunqing; Song, Yong; Li, Yazhou; Team, FDS

2013-01-01

Chinese Academy of Sciences (CAS) launched an engineering project to develop ADS system and lead-based reactors named China LEAd-based Reactor (CLEAR) series. The Institute of Nuclear Energy Safety Technology (INEST) will be responsible for the CLEAR design and R and D. In this project, CAS plans to develop the lead-based reactors through 3 phases which are 10MWth lead based research reactor (CLEAR-I), 100MWth lead-based experimental reactor (CLEAR-II), 1000MWth lead-based demonstration reactor (CLEAR-III). As a pre-testing facility, a lead-based zero-power reactor (CLEAR-0) is required to be built before CLEAR-I construction and operation. The new conceptual design of lead-based reactors, including hydrogen production, tritium production for fusion energy and thorium utilization, is also on-going. Lead-lithium cooled fusion reactor blanket design and lead-lithium experimental loops have been developed more than 10 years. CLEAR series reactor conceptual design has been finished and detailed engineering design for CLEAR-I is underway. The R and D activities for CLEAR reactor including design and safety software, key components, structural materials, lead-based experimental loops and neutronics experimental platform are developing. Series of liquid lead-based experimental loops named DRAGON (Lead-Lithium) and KYLIN (Lead-Bismuth) have already been built or on constructing to performed experiments investigating the structure material corrosion issues and the thermal-hydraulic properties of lead-based coolant. The Highly Intensified D-T Neutron Generator HINEG for neutron experiment and software validation will be constructed. Series advanced reactor design software and nuclear library have been developed for lead-alloy cooled reactor, including CAD based Multi-Functional 4D Neutronics Simulation System (Visual Bus), Monte Carlo Automatic Modeling Program for Radiation Transport Simulation (MCAM), Super Monte Carlo Simulation Program (SuperMC), Nuclear Radiation

How Do R&D Programs Funded by the Dg Xii (Science, Research and Development Directorate of the European Commission Impact the Upstream Oil and Gas Industry in Europe? Comment les programmes de R&D financés par la DG XII de la Commission européenne influencent-ils l'industrie pétrolière amont en Europe ?

Directory of Open Access Journals (Sweden)

Forbes P.

2006-12-01

Full Text Available This paper provides an overview of the direct and indirect impact which DG XII funding for research and development has on the oil and gas exploration and production industry in Europe. Despite the relatively low level of funding, the impact is quite significant. These impacts are presented using a bottom-up analysis, starting with the impact of technology on industry and society, the impact of research on technology, and the impact of DG XII funding on both research and technology for the exploration and production of oil and gas. The different aspects that are discussed include the direct impact, the impact on R&D organization and management, and the impact due to the Commission demonstration program for oil and gas (Thermie. Examples are provided from current and past project results. The future impact on the industry, and Commission policy toward the oil and gas sector are suggestedIn the near future, it is expected that there will be greater impact on production technologies, on the contribution of oil and gas companies to long-term R&D, and on the transfer of results to the Commission demonstration program. L'article apporte une vue d'ensemble sur la manière dont les financements de la DG XII pour la recherche et le développement (R&D ont une influence, directe ou indirecte, sur l'exploration et la production dans l'industrie du pétrole et du gaz en Europe. Le niveau de ces financements est présenté comme relativement faible de façon à mettre en évidence que, comparativement, leur répercution est très significative. L'impact de ces financements est abordé en couvrant successivement les effets sur la société, l'industrie, la technologie et finalement la recherche elle-même. Nous décrivons ici les influences de la technologie sur l'industrie et sur la société, puis les influences de la recherche sur la technologie et enfin celles des financements de la DG XII sur la recherche et la technologie en exploration-production. Diff

Leadership Under Challenge: Information Technology R&D in a Competitive World. An Assessment of the Federal Networking and Information Technology R&D Program

National Research Council Canada - National Science Library

Marburger, John H; Kvamme, E. F; Scalise, George; Reed, Daniel A

2007-01-01

...).That leadership is essential to U.S. economic prosperity, security, and quality of life. This report presents a formal assessment of the Federal Networking and Information Technology R&D (NITRD...

The returns to foreign R&D

NARCIS (Netherlands)

Belderbos, R.A.; Lokshin, B.; Sadowski, B.

2015-01-01

Extant research on R&D internationalization has not examined how effective foreign R&D investments are in generating positive returns for the investing firms, in particular in comparison and conjunction with the effects of domestic R&D investments. We examine the effectiveness of international

Captive R&D Offshoring

DEFF Research Database (Denmark)

Søberg, Peder Veng

This PhD thesis includes four journal papers and one book chapter, which investigate how newly established foreign-invested R&D units in emerging markets become able to carry out their mandates. In particular, the author investigates how the employees of such units acquire R&D home base knowledge...... Scandinavia and now operating in Scandinavia, China, and India. The thesis questions an assumption in the Uppsala model, which implies that different business activities can be internationalized in the same way. The findings point to the importance of socialization across the R&D home base and newly...... that the local talent in China and India is particularly suited to improving existing products and processes. However, due to a lack of social initiative, it is more difficult to use this talent to identify and solve entirely new problems. The thesis also investigates how local sources of knowledge are engaged...

Crowdsourced 'R&D' and medical research.

Science.gov (United States)

Callaghan, Christian William

2015-09-01

Crowdsourced R&D, a research methodology increasingly applied to medical research, has properties well suited to large-scale medical data collection and analysis, as well as enabling rapid research responses to crises such as disease outbreaks. Multidisciplinary literature offers diverse perspectives of crowdsourced R&D as a useful large-scale medical data collection and research problem-solving methodology. Crowdsourced R&D has demonstrated 'proof of concept' in a host of different biomedical research applications. A wide range of quality and ethical issues relate to crowdsourced R&D. The rapid growth in applications of crowdsourced R&D in medical research is predicted by an increasing body of multidisciplinary theory. Further research in areas such as artificial intelligence may allow better coordination and management of the high volumes of medical data and problem-solving inputs generated by the crowdsourced R&D process. © The Author 2015. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

A decade of DIII-D research. Final report for the period of work, October 1, 1989--September 30, 1998

Energy Technology Data Exchange (ETDEWEB)

NONE

1999-03-01

During the ten-year DIII-D tokamak operating period of 1989 through 1998, major scientific advances and discoveries were made and facility upgrades and improvements were implemented. Each year, annual reports as well as journal and international conference proceedings document the year-by-year advances (summarized in Section 7). This final contract report, provides a summary of these historical accomplishments. Section 2 encapsulates the 1998 status of DIII-D Fusion Science research. Section 3 summarizes the DIII-D facility operations. Section 4 describes the major upgrades to the DIII-D facility during this period. During the ten-year period, DIII-D has grown from predominantly a General Atomics program to a national center for fusion science with participants from over 50 collaborating institutions and 300 users who spend more than one week annually at DIII-D to carry out experiments or data analysis. In varying degrees, these collaborators participate in formulating the research program directions. The major collaborating institution programs are described in Section 6.

A decade of DIII-D research. Final report for the period of work, October 1, 1989--September 30, 1998

International Nuclear Information System (INIS)

1999-03-01

During the ten-year DIII-D tokamak operating period of 1989 through 1998, major scientific advances and discoveries were made and facility upgrades and improvements were implemented. Each year, annual reports as well as journal and international conference proceedings document the year-by-year advances (summarized in Section 7). This final contract report, provides a summary of these historical accomplishments. Section 2 encapsulates the 1998 status of DIII-D Fusion Science research. Section 3 summarizes the DIII-D facility operations. Section 4 describes the major upgrades to the DIII-D facility during this period. During the ten-year period, DIII-D has grown from predominantly a General Atomics program to a national center for fusion science with participants from over 50 collaborating institutions and 300 users who spend more than one week annually at DIII-D to carry out experiments or data analysis. In varying degrees, these collaborators participate in formulating the research program directions. The major collaborating institution programs are described in Section 6

Final report on the IAEA research contracts No. 1194/RB, 1194/R1/RB and 1194/R2/RB

International Nuclear Information System (INIS)

Zobor, E.; Janosy, J.S.; Szentgali, A.

1980-09-01

The final report summarizes the research activities made in the framework of the IAEA Research Contracts No. 1194/RB, 1194/R1/RB and 1194/R2/RB. A multilevel hierarchical control system is treated which uses weakly-coupled low dimensional subsystems under the supervision of a dynamic coordinator program. This self-organizing adaptive control system was checked by a 5 MW research reactor. As an example the paper describes the experimental computer control system of the 5 MW WWR-SM research reactor, where the reactor power and outlet temperature have been controlled on the basis of the treated control concept since 1978. (author)

IM-GEO: Impact of R and D on cost of geothermal power: Documentation of Model Version 2. 09

Energy Technology Data Exchange (ETDEWEB)

Petty, S.; Entingh, D.; Livesay, B.J.

1988-02-01

IM-GEO is an analysis used to estimate the impact of technology improvements on the relative cost of hydrothermal power. The analysis is available in a tutorial program for use on personal computers. It is designed for use by R and D program managers to evaluate R and D options. Only the potential impact of technologies is considered with all economic factors being held constant. This analysis has one unique feature. The economic impact of reducing risk by improving reservoir characterization is included using a strategy currently employed by financial institutions. This report describes the basis of the calculations, documents the code, and describes the operational procedures. Application of the code to study potential cost reductions due to R and D success will be done by R and D managers to evaluate and direct their own programs.

R&D+ i Strategic Management in a Public Company in the Brazilian Electric Sector

Directory of Open Access Journals (Sweden)

Ruy De Quadros Carvalho

2013-05-01

Full Text Available The purpose of this paper is - by reporting an experience of structuring processes and tools related to the strategic management of R&D in the electricity sector – to show the conditions and potential for improved efficiency, efficacy, and effectiveness in the R&D program set by ANEEL. The methodology is action research. This is because the proposed and tested model is the result of reflection and resolution of critical organizational issues, applied in a public company in the electric power sector. Act No. 9,991 of July 24, 2000 provides for the obligation on the part of concessionaires, permittees, and licensees in the electric power sector to invest part of their operating revenue in research and development (R&D. For the effective implementation of these legal obligations, companies prepare their annual R&D programs, comprising projects that aim at developing innovative solutions for their processes and increasing business efficiency. However, the urgency to comply with the contractual provisions, coupled with the small amount of experience most companies have when it comes to carrying out R&D activities and projects, has led to the gradual formation of a mode of R&D implementation and management that does not favor its optimization and alignment with the goals the utility companies and the sector’s own technological development . The approach proposed in this paper consists of structuring the processes and tools related to the management of R&D driven by innovation (R&D+i and aligned with with the business strategy. These processes include the adoption of procedures and tools to manage structured, integrated decision-making flows involved in the innovation process, aiming at full alignment with business goals and objectives.

R and D study on on-line criticality surveillance system (V)

International Nuclear Information System (INIS)

Yamada, Sumasu

2001-02-01

In view of necessity and importance of criticality surveillance systems for ensuring the safety of nuclear fuel manufacturing and reprocessing plants, 5-year basic studies and 4 year R and D studies on an on-line criticality surveillance system were carried out since 1991. This report is a summary of these series of studies. Noticing that the signal from a neutron detector is random in principle, these series of studies aimed to accumulate knowledge for developing an inexpensive criticality surveillance system with quick response based on the Auto-Regressive Moving Average (ARMA) model identification algorithm. During five-year basic studies on criticality surveillance system since 1991, we obtained knowledge required for developing a criticality surveillance system based on the ARMA model identification algorithm through 1) studies on recursive ARMA model identification algorithms most appropriate for estimating subcriticality form time series data under a steady state condition, 2) studies on pre-processing of signal from neutron detectors, 3) developing a new recursive ARMA model identification algorithm with small time delay to estimate time-dependent subcriticality, 4) proposing a basic concept for the elements required for an on-line criticality surveillance system, and 5) numerical analysis of data from the DCA experiments. During next four-year R and D studies on a criticality surveillance system since 1996, we 1) proposed modules required for a no-line criticality surveillance system, 2) revealed effectiveness of a adaptive digital filter (ADF) algorithm, as an important redundancy to the recursive ARMA model identification algorithm to be used in the signal processing module through numerical analysis of real data, 3) proposed a module of the Feynman-α method over γ ray signal and a fast signal processing module for γ ray signal, 4) developed a line-noise removal filter(Notch filter) and revealed its effectiveness for the DCA data corrupted with power

Managing R&D and New Product Development

NARCIS (Netherlands)

von Zedtwitz, Maximilian; Friesike, Sascha; Gassmann, Oliver; Dodgson, Mark; Gann, David M.; Phillips, Nelson

2014-01-01

This article examines the importance of R&D and new product development and explores their management. It describes three central aspects of managing R&D and new product development in firms: the product development funnel, R&D portfolio management, and R&D organization. Concepts such as the ‘fuzzy

Solid-State Lighting R&D Plan - 2016

Energy Technology Data Exchange (ETDEWEB)

None, None

2016-06-30

The SSL R&D Plan provides analysis and direction for ongoing R&D activities to advance SSL technology and increase energy savings. The R&D Plan also reviews SSL technology status and trends for both LEDs and OLEDs and offers an overview of the current DOE SSL R&D project portfolio.

R&D Challenges for SFR Design and Safety Analysis – Opportunities for International Cooperations

International Nuclear Information System (INIS)

Devictor, Nicolas

2013-01-01

Examples of R&D challenges related to safety have been presented. For any domain, R&D activities includes modelling, codes development and their V&V process, with the support of experimental programs. The success in the R&D will help the safety case and the acceptability of SFR. Some of these activities are relevant for international cooperation especially benchmarks and sharing of experimental facilities. This last point could take benefit of recent catalogues experimental facilities (already operational or in project), for example from the TAREF Task Force of OECD/NEA and the European project ADRIANA

High field accelerator magnet R&D in Europe

NARCIS (Netherlands)

Devred, A.; Baynham, D.E.; Bottura, L.; Chorowski, M; Fabbricatore, P.; Leroy, D.; den Ouden, A.; Rifflet, J.M.; Rossi, L.; Vincent-Viry, O.; Volpini, G.

2004-01-01

The LHC magnet R&D Program has shown that the limit of NbTi technology at 1.8 K was in the range 10 to 10.5 T. Hence, to go beyond the 10-T threshold, it is necessary to change of superconducting material. Given the state of the art in HTS, the only serious candidate is Nb/sub 3/Sn. A series of

Recent R and D around the Monte-Carlo code Tripoli-4 for criticality calculation

International Nuclear Information System (INIS)

Hugot, F.X.; Lee, Y.K.; Malvagi, F.

2008-01-01

TRIPOLI-4 [1] is the fourth generation of the TRIPOLI family of Monte Carlo codes developed from the 60's by CEA. It simulates the 3D transport of neutrons, photons, electrons and positrons as well as coupled neutron-photon propagation and electron-photons cascade showers. The code addresses radiation protection and shielding problems, as well as criticality and reactor physics problems through both critical and subcritical neutronics calculations. It uses full pointwise as well as multigroup cross-sections. The code has been validated through several hundred benchmarks as well as measurement campaigns. It is used as a reference tool by CEA as well as its industrial and institutional partners, and in the NURESIM [2] European project. Section 2 reviews its main features, with emphasis on the latest developments. Section 3 presents some recent R and D for criticality calculations. Fission matrix, Eigen-values and eigenvectors computations will be exposed. Corrections on the standard deviation estimator in the case of correlations between generation steps will be detailed. Section 4 presents some preliminary results obtained by the new mesh tally feature. The last section presents the interest of using XML format output files. (authors)

77 FR 1656 - Proposed Establishment of Restricted Areas R-5402, R-5403A, R-5403B, R-5403C, R-5403D, R-5403E, R...

Science.gov (United States)

2012-01-11

...-0117; Airspace Docket No. 09-AGL-31] RIN 2120-AI92 Proposed Establishment of Restricted Areas R-5402, R-5403A, R- 5403B, R-5403C, R-5403D, R-5403E, R-5403F; Devils Lake, ND AGENCY: Federal Aviation... Restricted Areas R-5402, R-5403A, R-5403B, R- 5403C, R-5403D, R-5403E, R-5403F; Devils Lake, ND (76 FR 72869...

77 FR 36907 - Establishment of Restricted Areas R-5402, R-5403A, R-5403B, R-5403C, R-5403D, R-5403E, and R...

Science.gov (United States)

2012-06-20

...; Airspace Docket No. 09-AGL-31] Establishment of Restricted Areas R-5402, R-5403A, R-5403B, R- 5403C, R-5403D, R-5403E, and R-5403F; Devils Lake, ND AGENCY: Federal Aviation Administration (FAA), DOT. ACTION... establish Restricted Areas R- 5402, R-5403A, R-5403B, R-5403C, R-5403D, R-5403E, and R-5403F in the vicinity...

Vertically integrated ZnO-Based 1D1R structure for resistive switching

International Nuclear Information System (INIS)

Zhang Yang; Duan Ziqing; Li Rui; Ku, Chieh-Jen; Reyes, Pavel I; Ashrafi, Almamun; Zhong Jian; Lu Yicheng

2013-01-01

We report a ZnO-based 1D1R structure, which is formed by a vertical integration of a FeZnO/MgO switching resistor (1R) and an Ag/MgZnO Schottky diode (1D). The multifunctional ZnO and its compounds are grown through MOCVD with in situ doping. For the R element, the current ratio of the high-resistance state (HRS) over the low-resistance state (LRS) at 1 V is 2.4 × 10 6 . The conduction mechanisms of the HRS and LRS are Poole–Frenkel emission and resistive conduction, respectively. The D element shows the forward/reverse current ratio at ±1 V to be 2.4 × 10 7 . This 1D1R structure exhibits high R HRS /R LRS ratio, excellent rectifying characteristics and robust retention. (paper)

Digit ratio (2D:4D) in primary brain tumor patients: A case-control study.

Science.gov (United States)

Bunevicius, Adomas; Tamasauskas, Sarunas; Deltuva, Vytenis Pranas; Tamasauskas, Arimantas; Sliauzys, Albertas; Bunevicius, Robertas

2016-12-01

The second-to-fourth digit ratio (2D:4D) reflects prenatal estrogen and testosterone exposure, and is established in utero. Sex steroids are implicated in development and progression of primary brain tumors. To investigate whether there is a link between 2D:4D ratio and primary brain tumors, and age at presentation. Digital images of the right and left palms of 85 primary brain tumor patients (age 56.96±13.68years; 71% women) and 106 (age 54.31±13.68years; 68% women) gender and age matched controls were obtained. The most common brain tumor diagnoses were meningioma (41%), glioblastoma (20%) and pituitary adenoma (16%). Right and left 2D:4D ratios, and right minus left 2D:4D (D r-l ) were compared between patients and controls, and were correlated with age. Right and left 2D:4D ratios were significantly lower in primary brain tumor patients relative to controls (t=-4.28, pbrain tumor patients and controls (p=0.27). In meningioma and glioma patients, age at presentation correlated negatively with left 2D:4D ratio (rho=-0.42, p=0.01 and rho=-0.36, p=0.02, respectively) and positively with D r-l (rho=0.45, p=0.009 and rho=0.65, p=0.04, respectively). Right and left hand 2D:4D ratios are lower in primary brain tumor patients relative to healthy individuals suggesting greater prenatal testosterone and lower prenatal estrogen exposure in brain tumor patients. Greater age at presentation is associated with greater D r-l and with lower left 2D:4D ratio of meningioma and glioma patients. Due to small sample size our results should be considered preliminary and interpreted with caution. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

4-D OCT in Developmental Cardiology

Science.gov (United States)

Jenkins, Michael W.; Rollins, Andrew M.

Although strong evidence exists to suggest that altered cardiac function can lead to CHDs, few studies have investigated the influential role of cardiac function and biophysical forces on the development of the cardiovascular system due to a lack of proper in vivo imaging tools. 4-D imaging is needed to decipher the complex spatial and temporal patterns of biomechanical forces acting upon the heart. Numerous solutions over the past several years have demonstrated 4-D OCT imaging of the developing cardiovascular system. This chapter will focus on these solutions and explain their context in the evolution of 4-D OCT imaging. The first sections describe the relevant techniques (prospective gating, direct 4-D imaging, retrospective gating), while later sections focus on 4-D Doppler imaging and measurements of force implementing 4-D OCT Doppler. Finally, the techniques are summarized, and some possible future directions are discussed.

miR-181b functions as an oncomiR in colorectal cancer by targeting PDCD4

Directory of Open Access Journals (Sweden)

Yanqing Liu

2016-09-01

Full Text Available Abstract Programmed cell death 4 (PDCD4 is a RNA-binding protein that acts as a tumor suppressor in many cancer types, including colorectal cancer (CRC. During CRC carcinogenesis, PDCD4 protein levels remarkably decrease, but the underlying molecular mechanism for decreased PDCD4 expression is not fully understood. In this study, we performed bioinformatics analysis to identify miRNAs that potentially target PDCD4. We demonstrated miR-181b as a direct regulator of PDCD4. We further showed that activation of IL6/STAT3 signaling pathway increased miR-181b expression and consequently resulted in downregulation of PDCD4 in CRC cells. In addition, we investigated the biological effects of PDCD4 inhibition by miR-181b both in vitro and in vivo and found that miR-181b could promote cell proliferation and migration and suppress apoptosis in CRC cells and accelerate tumor growth in xenograft mice, potentially through targeting PDCD4. Taken together, this study highlights an oncomiR role for miR-181b in regulating PDCD4 in CRC and suggests that miR-181b may be a novel molecular therapeutic target for CRC.

ATLAS Cloud R&D

Science.gov (United States)

Panitkin, Sergey; Barreiro Megino, Fernando; Caballero Bejar, Jose; Benjamin, Doug; Di Girolamo, Alessandro; Gable, Ian; Hendrix, Val; Hover, John; Kucharczyk, Katarzyna; Medrano Llamas, Ramon; Love, Peter; Ohman, Henrik; Paterson, Michael; Sobie, Randall; Taylor, Ryan; Walker, Rodney; Zaytsev, Alexander; Atlas Collaboration

2014-06-01

The computing model of the ATLAS experiment was designed around the concept of grid computing and, since the start of data taking, this model has proven very successful. However, new cloud computing technologies bring attractive features to improve the operations and elasticity of scientific distributed computing. ATLAS sees grid and cloud computing as complementary technologies that will coexist at different levels of resource abstraction, and two years ago created an R&D working group to investigate the different integration scenarios. The ATLAS Cloud Computing R&D has been able to demonstrate the feasibility of offloading work from grid to cloud sites and, as of today, is able to integrate transparently various cloud resources into the PanDA workload management system. The ATLAS Cloud Computing R&D is operating various PanDA queues on private and public resources and has provided several hundred thousand CPU days to the experiment. As a result, the ATLAS Cloud Computing R&D group has gained a significant insight into the cloud computing landscape and has identified points that still need to be addressed in order to fully utilize this technology. This contribution will explain the cloud integration models that are being evaluated and will discuss ATLAS' learning during the collaboration with leading commercial and academic cloud providers.

Metholology for the selection of LWR safety R and D projects. Phase I, status report

International Nuclear Information System (INIS)

El-Sheikh, K.A.

1980-03-01

The objective of the LWR R and D Selection Methodology Program is to develop and demonstrate an R and D selection methodology appropriate for LWR safety technology. This report documents the development work from the program beginning in April, 1979 to the end of Fiscal Year 1979. The scope of work for this period included three tasks; methodology review (Task 1), measures development (Task 2), and methodology development for the first phase of application (Task 3). The accomplishments of these tasks are presented

Functional Programming in R

DEFF Research Database (Denmark)

Mailund, Thomas

Master functions and discover how to write functional programs in R. In this book, you'll make your functions pure by avoiding side-effects; you’ll write functions that manipulate other functions, and you’ll construct complex functions using simpler functions as building blocks. In Functional...... Programming in R, you’ll see how we can replace loops, which can have side-effects, with recursive functions that can more easily avoid them. In addition, the book covers why you shouldn't use recursion when loops are more efficient and how you can get the best of both worlds. Functional programming...... is a style of programming, like object-oriented programming, but one that focuses on data transformations and calculations rather than objects and state. Where in object-oriented programming you model your programs by describing which states an object can be in and how methods will reveal or modify...

Functional Programming in R

DEFF Research Database (Denmark)

Mailund, Thomas

2017-01-01

Master functions and discover how to write functional programs in R. In this book, you'll make your functions pure by avoiding side-effects; you’ll write functions that manipulate other functions, and you’ll construct complex functions using simpler functions as building blocks. In Functional...... Programming in R, you’ll see how we can replace loops, which can have side-effects, with recursive functions that can more easily avoid them. In addition, the book covers why you shouldn't use recursion when loops are more efficient and how you can get the best of both worlds. Functional programming...... is a style of programming, like object-oriented programming, but one that focuses on data transformations and calculations rather than objects and state. Where in object-oriented programming you model your programs by describing which states an object can be in and how methods will reveal or modify...

Overview of TBM R and D activities in India

Energy Technology Data Exchange (ETDEWEB)

Rajendra Kumar, E., E-mail: rajendrakumare@gmail.com [Institute for Plasma Research, Bhat, Gandhinagar 382428 (India); Jayakumar, T. [Indira Gandhi Centre for Atomic Research, Kalpakkam 603102 (India); Suri, A.K. [Materials Group, Bhabha Atomic Research Centre, Mumbai 400085 (India)

2012-08-15

In India, development of Lead-Lithium Ceramic Breeder (LLCB) blanket is being performed as the primary candidate of Test Blanket Module (TBM) towards DEMO reactor. The LLCB TBM will be tested from the first phase of ITER operation (H-H phase) in one-half of an ITER port no. 2. The Indian TBM R and D program is focused on the development of blanket materials and critical technologies: structural material (IN-RAFMS), breeding materials (Pb-Li, Li{sub 2}TiO{sub 3}), development of technologies for Lead-Lithium cooling system (LLCS), helium cooling system (HCS), tritium extraction system (TES) and TBM related fabrication technologies. This paper will provide an overview of LLCB TBM R and D activities under progress in India.

A top-down analysis: Determining photovoltaics R and D investments from patent analysis and R and D headcount

International Nuclear Information System (INIS)

Breyer, Christian; Birkner, Christian; Meiss, Jan; Goldschmidt, Jan Christoph; Riede, Moritz

2013-01-01

For alternative energy technologies like photovoltaics (PV), the analysis of Research and Development (R and D) expenses is important to observe and understand market dynamics. This is, in turn, essential for policymakers. However, the quantitative evaluation of global corporate R and D investments is a challenging task due to unavailability or high scatter of precise data. Here we present a top-down approach to estimate the current and global historic cumulated PV R and D investments based on international PV patent applications. High growth rates of PV-related patents and R and D headcount accompany growth and development of the PV market and are an excellent indicator to analyze R and D investments. With this approach, current annual corporate PV R and D investments are found to be about 6000 m€ and show a rapidly increasing trend on a global scale. - Highlights: • Global corporate and public photovoltaic R and D spendings are presented and quantified. • Instead of company reports or governmental reports, alternative metrics are developed. • Basis for quantification are photovoltaic patent applications and research headcounts. • Patents are analyzed regarding their country of origin, year of filing, type of technology. • Ethical and political implications of energy R and D are discussed

Gauged R-symmetry and its anomalies in 4D N=1 supergravity and phenomenological implications

CERN Document Server

Antoniadis, I.; Knoops, R.

2015-01-01

We consider a class of models with gauged U(1)_R symmetry in 4D N=1 supergravity that have, at the classical level, a metastable ground state, an infinitesimally small (tunable) positive cosmological constant and a TeV gravitino mass. We analyse if these properties are maintained under the addition of visible sector (MSSM-like) and hidden sector state(s), where the latter may be needed for quantum consistency. We then discuss the anomaly cancellation conditions in supergravity as derived by Freedman, Elvang and K\\"ors and apply their results to the special case of a U(1)_R symmetry, in the presence of the Fayet-Iliopoulos term ($\\xi$) and Green-Schwarz mechanism(s). We investigate the relation of these anomaly cancellation conditions to the "naive" field theory approach in global SUSY, in which case U(1)_R cannot even be gauged. We show the two approaches give similar conditions. Their induced constraints at the phenomenological level, on the above models, remain strong even if one lifted the GUT-like conditi...

Network configuration of global R&D networks

DEFF Research Database (Denmark)

Hansen, Zaza Nadja Lee; Srai, Jagjit Singh

2011-01-01

, network configuration of global R&D has tended to focus on strategic elements with limited attention given operational effectiveness, or to interfaces with downstream manufacturing operations. Within OM literature, the drivers of configuration of global networks within, engineering, production, supply...... to R&D networks emerged, e.g. product features were more prominent in R&D networks. Furthermore, the study has shown extensive interaction with other operations, including many downstream manufacturing operations. By extending the OM configuration concepts to the configuration of R&D networks......Companies are increasingly globalising their R&D activities, both within the firms and with external partners, with consequent implications for their interaction with manufacturing operations. Previous research in R&D networks has focused on coordination, governance and support elements. However...

76 FR 19899 - National D.A.R.E. Day, 2011

Science.gov (United States)

2011-04-11

..., and neighbors also have roles to play in helping adolescents understand the dangers of alcohol and... often a critical partner in implementing community-based drug abuse prevention strategies. The Drug Abuse Resistance Education (D.A.R.E.) program, in addition to many other prevention efforts across our...

planSOEC. R and D and commercialization roadmap for SOEC electrolysis. R and D of SOEC stacks with improved durability. Project report

Energy Technology Data Exchange (ETDEWEB)

Richter, A.; Friis Pedersen, C.; Nielsen, Jens Ulrik [Topsoe Fuel Cells A/S, Kgs. Lyngby (Denmark); Mogensen, M.; Hoejgaard Jensen, S.; Ming Chen [Technical Univ. of Denmark. Fuel Cells and Solid State Chemistry Div., DTU Risoe Campus, Roskilde (Denmark); Sloth, M. [H2 Logic A/S, Herning (Denmark)

2011-05-15

The project has been divided into two parts: PART 1: Formulation of a R and D and commercialization roadmap for SOEC electrolysis. PART 2: Conducting R and D of SOEC stacks with improved durability. The purpose of Part 1 has been to develop a R and D and commercialisation roadmap for hydrogen and CO production plants based on the solid oxide electrolysis cell (SOEC) technology. SOEC technology is still on an early R and D stage but years of extensive R and D within SOFC technology provides a strong platform for an accelerated commercialisation. However, in order to guide the future SOEC R and D activities towards reaching commercial market requirements a detailed roadmap is necessary. An overall strategy for R and D of various electrolysis technologies in Denmark already exists{sup 2}, formulated in the Hydrogen Production working group in the Danish Hydrogen and Fuel Cell Partnership. The SOEC roadmap developed as part of the planSOEC project supplements the overall strategy, by conducting an updated analysis of state-of-the-art. Also planSOEC provides a detailed analysis of requirements for different market applications for SOEC, which enables formulation of precise and detailed R and D targets. The objectives of Part 2 in this project were multiple: 1) To investigate durability of solid oxide cells (SOCs) and stack components under industrially relevant (''harsh'') electrolysis operating conditions; 2) to investigate performance of standard TOFC (Topsoe Fuel Cell A/S) SOC stacks (based on state-of-the-art solid oxide cells) under mild electrolysis operating conditions ({<=}0.75 A/cm{sup 2}); 3) to further develop SOEC stack computer models available at Riso DTU and TOFC. Accordingly four lines of work were carried out in the here reported project: 1) Investigation of corrosion resistance of interconnect alloys. 2) Cell and stack element testing. 3) SOEC stack testing. 4) SOEC stack modeling. (LN)

Analysis of various types of single-polypeptide-chain (sc) heterodimeric A{sub 2A}R/D{sub 2}R complexes and their allosteric receptor–receptor interactions

Energy Technology Data Exchange (ETDEWEB)

Kamiya, Toshio, E-mail: kamiya@z2.keio.jp [Department of Molecular Cell Signaling, Tokyo Metropolitan Institute for Neuroscience, 2-6 Musashidai, Fuchu, Tokyo 183-8526 (Japan); Department of Neurology, Tokyo Metropolitan Institute for Neuroscience, 2-6 Musashidai, Fuchu, Tokyo 183-8526 (Japan); Cell Biology Laboratory, School of Pharmaceutical Sciences, Kinki University, 3-4-1 Kowakae, Higashi-Osaka, Osaka 577-8502 (Japan); Yoshioka, Kazuaki; Nakata, Hiroyasu [Department of Molecular Cell Signaling, Tokyo Metropolitan Institute for Neuroscience, 2-6 Musashidai, Fuchu, Tokyo 183-8526 (Japan)

2015-01-09

Highlights: • Various scA{sub 2A}R/D{sub 2}R constructs, with spacers between the two receptors, were created. • Using whole cell binding assay, constructs were examined for their binding activity. • Although the apparent ratio of A{sub 2A}R to D{sub 2}R binding sites should be 1, neither was 1. • Counter agonist-independent binding cooperativity occurred in context of scA{sub 2A}R/D{sub 2}R. - Abstract: Adenosine A{sub 2A} receptor (A{sub 2A}R) heteromerizes with dopamine D{sub 2} receptor (D{sub 2}R). However, these class A G protein-coupled receptor (GPCR) dimers are not fully formed, but depend on the equilibrium between monomer and dimer. In order to stimulate the heteromerization, we have previously shown a successful design for a fusion receptor, single-polypeptide-chain (sc) heterodimeric A{sub 2A}R/D{sub 2}R complex. Here, using whole cell binding assay, six more different scA{sub 2A}R/D{sub 2}R constructs were examined. Not only in scA{sub 2A}R/D{sub 2}R ‘liberated’ with longer spacers between the two receptors, which confer the same configuration as the prototype, the A{sub 2A}R-odr4TM-D{sub 2L}R, but differ in size (Forms 1–3), but also in scA{sub 2A}R/D{sub 2L}R (Form 6) fused with a transmembrane (TM) of another type II TM protein, instead of odr4TM, neither of their fixed stoichiometry (the apparent ratios of A{sub 2A}R to D{sub 2}R binding sites) was 1, suggesting their compact folding. This suggests that type II TM, either odr4 or another, facilitates the equilibrial process of the dimer formation between A{sub 2A}R and D{sub 2L}R, resulting in the higher-order oligomer formation from monomer of scA{sub 2A}R/D{sub 2L}R itself. Also, in the reverse type scA{sub 2A}R/D{sub 2L}R, i.e., the D{sub 2L}R-odr4TM-A{sub 2A}R, counter agonist-independent binding cooperativity (cooperative folding) was found to occur (Forms 4 and 5). In this way, the scA{sub 2A}R/D{sub 2L}R system has unveiled the cellular phenomenon as a snapshot of the

The R-matrix of the Uq(d4(3)) algebra and g2(1) affine Toda field theory

International Nuclear Information System (INIS)

Takacs, G.

1997-01-01

The R-matrix of the U q (d 4 (3) ) algebra is constructed in the 8-dimensional fundamental representation. Using this result, an exact S-matrix is conjectured for the imaginary coupled g 2 (1) affine Toda field theory, the structure of which is found to be very similar to the previously investigated S-matrix of d 4 (3) Toda theory. It is shown that this S-matrix is consistent with the results for the case of real coupling using the breather-particle correspondence. For q a root of unity it is argued that the theory can be restricted to yield Φ(11 vertical stroke 12) perturbations of WA 2 minimal models. (orig.)

US Department of Energy investments in natural gas R ampersand D: An analysis of the gas industry proposal

International Nuclear Information System (INIS)

Sutherland, R.J.

1992-01-01

The natural gas industry has proposed an increase in the DOE gas R ampersand D budget from about $100 million to about $250 million per year for each of the next 10 years. The proposal includes four programs: natural gas supplies, fuel cells, natural gas vehicles and stationary combustion systems. This paper is a qualitative assessment of the gas industry proposal and recommends a natural gas R ampersand D strategy for the DOE. The methodology is a conceptual framework based on an analysis of market failures and the energy policy objectives of the DOE's (1991) National Energy Strategy. This framework would assist the DOE in constructing an R ampersand D portfolio that achieves energy policy objectives. The natural gas supply program is recommended to the extent that it contributes to energy price stability. Stationary combustion programs are supported on grounds of economic efficiency and environmental quality. The fuel cell program is supported on grounds of environmental quality. The natural gas vehicle program may potentially contribute to environmental quality and energy price stability. The R ampersand D programs in natural gas vehicles and in fuel cells should be complemented with policies that encourage the commercialization and use of the technology, not merely its development

R and D contract management systems in the USA (Attachment); Beikoku ni okeru R and D contract kanri system (tenpu shiryohen)

Energy Technology Data Exchange (ETDEWEB)

NONE

2001-02-01

Presented herein is the attachment for 'R and D contract management systems in the USA'. The major contents include regulations governing the R and D contracts, procedures for the R and D contracts, financial procedures for the R and D contracts, procedures for the alternative R and D contracts, financial management of the R and D contracts, and activities for the management of the contract processes by electronic systems. (NEDO)

Research and development on super heat pump energy accumulation system. Final report

Energy Technology Data Exchange (ETDEWEB)

NONE

1993-06-01

This is the final report on research and development of super heat pump energy accumulation system, which has been carried out from FY 1985 to 1992. It describes outline of the research and development program, R and D results, final evaluation methodology, evaluation of the R and D, proposals for the commercialization, and so on. The super high performance compression heat pumps are technically evaluated for highly efficient type (for heating, and cooling and heating), high temperature type (utilizing high temperature heat source, and low temperature heat source), working fluids (alcohol-based and nonalcohol-based), stainless steel plate fin type heat exchanger, EHD heat exchanger, and so on. The other techniques evaluated include those for chemical heat storage, combined systems, plant simulation, and systemization. The evaluation works are also directed to the economic and environmental aspects. Finally, the R and D themes are proposed to leap over various hurdles, e.g., reliability and economic viability, for the eventual commercialization of the energy accumulation system. (NEDO)

Programming Graphical User Interfaces in R

CERN Document Server

Verzani, John

2012-01-01

Programming Graphical User Interfaces with R introduces each of the major R packages for GUI programming: RGtk2, qtbase, Tcl/Tk, and gWidgets. With examples woven through the text as well as stand-alone demonstrations of simple yet reasonably complete applications, the book features topics especially relevant to statisticians who aim to provide a practical interface to functionality implemented in R. The book offers: A how-to guide for developing GUIs within R The fundamentals for users with limited knowledge of programming within R and other languages GUI design for specific functions or as l

New Measurement of {ital B} {r_arrow} {ital D}{sup {asterisk}}{ital {pi}} Branching Fractions

Energy Technology Data Exchange (ETDEWEB)

Brandenburg, G.; Briere, R.A.; Gao, Y.S.; Kim, D.Y.; Wilson, R.; Yamamoto, H. [Harvard University, Cambridge, Massachusetts 02138 (United States); Browder, T.E.; Li, F.; Li, Y.; Rodriguez, J.L. [University of Hawaii at Manoa, Honolulu, Hawaii 96822 (United States); Bergfeld, T.; Eisenstein, B.I.; Ernst, J.; Gladding, G.E.; Gollin, G.D.; Hans, R.M.; Johnson, E.; Karliner, I.; Marsh, M.A.; Palmer, M.; Selen, M.; Thaler, J.J. [University of Illinois, Champaign-Urbana, Illinois 61801 (United States); Edwards, K.W.; Edwards, K.W. [the Institute of Particle Physics (Canada); Bellerive, A.; Bellerive, A.; Janicek, R.; Janicek, R.; MacFarlane, D.B.; MacFarlane, D.B.; McLean, K.W.; McLean, K.W.; Patel, P.M.; Patel, P.M. [the Institute of Particle Physics (Canada); Sadoff, A.J. [Ithaca College, Ithaca, New York 14850 (United States); Ammar, R.; Baringer, P.; Bean, A.; Besson, D.; Coppage, D.; Darling, C.; Davis, R.; Hancock, N.; Kotov, S.; Kravchenko, I.; Kwak, N. [University of Kansas, Lawrence, Kansas 66045 (United States); Anderson, S.; Kubota, Y.; Lattery, M.; Lee, S.J.; ONeill, J.J.; Patton, S.; Poling, R.; Riehle, T.; Savinov, V.; Smith, A. [University of Minnesota, Minneapolis, Minnesota 55455 (United States); Alam, M.S.; Athar, S.B.; Ling, Z.; Mahmood, A.H.; Severini, H.; Timm, S.; Wappler, F. [State University of New York at Albany, Albany, New York 12222 (United States); Anastassov, A.; Blinov, S.; Duboscq, J.E.; Fisher, K.D.; Fujino, D.; Fulton, R.; Gan, K.K.; Hart, T.; Honscheid, K.; Kagan, H.; Kass, R.; Lee, J.; Spencer, M.B.; Sung, M.; Undrus, A.; Wanke, R.; Wolf, A.; Zoeller, M.M. [Ohio State University, Columbus, Ohio 43210 (United States); Nemati, B.; Richichi, S.J.; Ross, W.R.; Skubic, P.; Wood, M. [University of Oklahoma, Norman, Oklahoma 73019 (United States); Bishai, M.; Fast, J.; Gerndt, E.; Hinson, J.W.; Menon, N.; Miller, D.H.; Shibata, E.I.; Shipsey, I.P.; Yurko, M. [Purdue University, West Lafayette, Indiana 47907 (United States)

1998-03-01

The decays {Upsilon}(4S){r_arrow}B{ovr B} , followed by B{r_arrow}D{sup {asterisk}}{pi} and D{sup {asterisk}}{r_arrow}D{pi} , permit reconstruction of all kinematic quantities that describe the sequence without reconstruction of the D , with reasonably low backgrounds. Using an integrated e{sup +}e{sup {minus}} luminosity of 3.1 fb{sup {minus}1} accumulated at the {Upsilon}(4S) by the CLEO-II detector, we report measurements of B({ovr B}{sup 0}{r_arrow} D{sup {asterisk}+}{pi}{sup {minus}})=(2.81{plus_minus} 0.11{plus_minus}0.21{plus_minus}0.05){times}10{sup {minus}3} and B(B{sup {minus}}{r_arrow}D{sup {asterisk}0}{pi}{sup {minus}})=(4.34{plus_minus}0.33{plus_minus}0.34{plus_minus}0.1 8){times}10{sup {minus}3} . {copyright} {ital 1998} {ital The American Physical Society}

R and D contract management systems in the USA (Attachment); Beikoku ni okeru R and D contract kanri system (tenpu shiryohen)

Energy Technology Data Exchange (ETDEWEB)

NONE

2001-02-01

Presented herein is the attachment for 'R and D contract management systems in the USA'. The major contents include regulations governing the R and D contracts, procedures for the R and D contracts, financial procedures for the R and D contracts, procedures for the alternative R and D contracts, financial management of the R and D contracts, and activities for the management of the contract processes by electronic systems. (NEDO)

R and D ekes out an increase in FY 2015 budget request

Energy Technology Data Exchange (ETDEWEB)

Kramer, David

2014-05-01

With spending caps in place, President Obama proposes an off-budget fund to support additional R and D. NASA would ground a flying observatory, and DOE would sharply curtail its nonproliferation programs.

Strategic management of government-sponsored R&D portfolios

OpenAIRE

Barry Bozeman; Juan Rogers

2001-01-01

Although strategic management of R&D portfolios is common practice in private sector R&D, government R&D management tends to be more discrete and ad hoc, focusing on generating maximum output from individual projects. Often, there is no clear notion of the desired public sector output. Whereas private sector R&D evaluation is generally straightforward, with the function of R&D being measured in terms of a company's internal return on investment, the benefits of public-sponsored R&D tend to be...

ECG-based 4D-dose reconstruction of cardiac arrhythmia ablation with carbon ion beams: application in a porcine model

Science.gov (United States)

Richter, Daniel; Immo Lehmann, H.; Eichhorn, Anna; Constantinescu, Anna M.; Kaderka, Robert; Prall, Matthias; Lugenbiel, Patrick; Takami, Mitsuru; Thomas, Dierk; Bert, Christoph; Durante, Marco; Packer, Douglas L.; Graeff, Christian

2017-09-01

Noninvasive ablation of cardiac arrhythmia by scanned particle radiotherapy is highly promising, but especially challenging due to cardiac and respiratory motion. Irradiations for catheter-free ablation in intact pigs were carried out at the GSI Helmholtz Center in Darmstadt using scanned carbon ions. Here, we present real-time electrocardiogram (ECG) data to estimate time-resolved (4D) delivered dose. For 11 animals, surface ECGs and temporal structure of beam delivery were acquired during irradiation. R waves were automatically detected from surface ECGs. Pre-treatment ECG-triggered 4D-CT phases were synchronized to the R-R interval. 4D-dose calculation was performed using GSI’s in-house 4D treatment planning system. Resulting dose distributions were assessed with respect to coverage (D95 and V95), heterogeneity (HI  =  D5-D95) and normal tissue exposure. Final results shown here were performed offline, but first calculations were started shortly after irradiation The D95 for TV and PTV was above 95% for 10 and 8 out of 11 animals, respectively. HI was reduced for PTV versus TV volumes, especially for some of the animals targeted at the atrioventricular junction, indicating residual interplay effects due to cardiac motion. Risk structure exposure was comparable to static and 4D treatment planning simulations. ECG-based 4D-dose reconstruction is technically feasible in a patient treatment-like setting. Further development of the presented approach, such as real-time dose calculation, may contribute to safe, successful treatments using scanned ion beams for cardiac arrhythmia ablation.

Evaluating firms' R&D performance using best worst method.

Science.gov (United States)

Salimi, Negin; Rezaei, Jafar

2018-02-01

Since research and development (R&D) is the most critical determinant of the productivity, growth and competitive advantage of firms, measuring R&D performance has become the core of attention of R&D managers, and an extensive body of literature has examined and identified different R&D measurements and determinants of R&D performance. However, measuring R&D performance and assigning the same level of importance to different R&D measures, which is the common approach in existing studies, can oversimplify the R&D measuring process, which may result in misinterpretation of the performance and consequently fallacy R&D strategies. The aim of this study is to measure R&D performance taking into account the different levels of importance of R&D measures, using a multi-criteria decision-making method called Best Worst Method (BWM) to identify the weights (importance) of R&D measures and measure the R&D performance of 50 high-tech SMEs in the Netherlands using the data gathered in a survey among SMEs and from R&D experts. The results show how assigning different weights to different R&D measures (in contrast to simple mean) results in a different ranking of the firms and allow R&D managers to formulate more effective strategies to improve their firm's R&D performance by applying knowledge regarding the importance of different R&D measures. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.