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Sample records for quality factors approaching

  1. Human factors systems approach to healthcare quality and patient safety

    Science.gov (United States)

    Carayon, Pascale; Wetterneck, Tosha B.; Rivera-Rodriguez, A. Joy; Hundt, Ann Schoofs; Hoonakker, Peter; Holden, Richard; Gurses, Ayse P.

    2013-01-01

    Human factors systems approaches are critical for improving healthcare quality and patient safety. The SEIPS (Systems Engineering Initiative for Patient Safety) model of work system and patient safety is a human factors systems approach that has been successfully applied in healthcare research and practice. Several research and practical applications of the SEIPS model are described. Important implications of the SEIPS model for healthcare system and process redesign are highlighted. Principles for redesigning healthcare systems using the SEIPS model are described. Balancing the work system and encouraging the active and adaptive role of workers are key principles for improving healthcare quality and patient safety. PMID:23845724

  2. Factors influencing groundwater quality: towards an integrated management approach.

    Science.gov (United States)

    De Giglio, O; Quaranta, A; Barbuti, G; Napoli, C; Caggiano, G; Montagna, M T

    2015-01-01

    The safety of groundwater resources is a serious issue, particularly when these resources are the main source of water for drinking, irrigation and industrial use in coastal areas. In Italy, 85% of the water used by the public is of underground origin. The aim of this report is to analyze the main factors that make groundwater vulnerable. Soil characteristics and filtration capacity can promote or hinder the diffusion of environmental contaminants. Global climate change influences the prevalence and degree of groundwater contamination. Anthropic pressure causes considerable exploitation of water resources, leading to reduced water availability and the progressive deterioration of water quality. Management of water quality will require a multidisciplinary, dynamic and practical approach focused on identifying the measures necessary to reduce contamination and mitigate the risks associated with the use of contaminated water resources.

  3. Approaching Safety through Quality: Factors Influencing College Student Perceptions.

    Science.gov (United States)

    Ramaswamy, S K; Mosher, G A

    2016-04-01

    Quality management practices have been identified by previous literature as a factor that could potentially reduce the level of safety incidents and hazards in agricultural work environments. The present study used multivariate analysis to examine the effect of independent variables such as quality and safety awareness, work experience, safety and quality management experience, and the perceived importance of safety and quality on the role of quality management practices as a mitigating factor for safety hazards and incidents in agriculture. Variables were measured on a five-point scale using a survey questionnaire. Data were collected from approximately 900 undergraduates enrolled in the College of Agriculture and Life Sciences at a large land grant university in the U.S. The level of student work experience and student perceptions of the importance of quality explained a significant amount of the variance in student views of quality management practices as a mitigating factor for safety hazards and incidents. The findings of this study provide further evidence for using quality management practices as a basis for safety interventions targeted at the agricultural workforce.

  4. QUALITY MANAGEMENT IN THE SUPPLY CHAIN: ANALYTICAL APPROACHES AND FACTORS TO DETERMINE OPTIMAL QUALITY LEVELS

    OpenAIRE

    Shetty, Tushar

    2015-01-01

    Quality has been identified as an important component for each and every business, irrespective of their size and type, and hence, quality affects each and every activity of an organization crucial for their success. Therefore, since recent times, almost every organization has identified the need of perceiving quality and its management across the supply chain. There are a number of factors affecting the maintenance and management of quality across supply chain. As the topic itself his ...

  5. Electrically Small Magnetic Dipole Antennas With Quality Factors Approaching the Chu Lower Bound

    DEFF Research Database (Denmark)

    Kim, Oleksiy S.; Breinbjerg, Olav; Yaghjian, Arthur D.

    2010-01-01

    permeability yields the quality factor Q that constitutes the lower bound for a magnetic dipole antenna with a magneto-dielectric core. Furthermore, the smaller the antenna the closer its quality factor Q can approach the Chu lower bound. Simulated results for the TE10-mode multiarm spherical helix antenna......We investigate the quality factor Q for electrically small current distributions and practical antenna designs radiating the TE10 magnetic dipole field. The current distributions and the antenna designs employ electric currents on a spherical surface enclosing a magneto-dielectric material...... numerically. It is found that for a given antenna size and permittivity there is an optimum permeability that ensures the lowest possible Q, and this optimum permeability is inversely proportional to the square of the antenna electrical radius. When the relative permittivity is equal to 1, the optimum...

  6. Developing Student Housing Quality Scale in Higher Institutions of Learning: A Factor Analysis Approach

    Directory of Open Access Journals (Sweden)

    F. K. Bondinuba

    2013-01-01

    Full Text Available The researchers developed an instrument for measuring student housing quality (SHQ in Higher Institutions of Learning (HIL in Ghana. The paper sought to validate the student housing quality scale (SHOQUAL through factor analysis approach. 700 respondents were sampled from two public HIL in Ghana in a cross-sectional survey that used a self-administered structured questionnaire for data collection. Confirmatory factor fnalysis (CFA was conducted to detect the underlying latent variables that significantly determine SHQ in Ghanaian HIL. The findings indicate that four emerged SHQ dimensions relevant to the research context were labelled as follows: core facility quality, enabling facility quality, support facility quality, and cost of housing. The constructs in the derived model possess high reliability and validity. Student housing service providers could conveniently use the derived instrument items for measuring SHQ in HIL. Implications are discussed and limitations are noted. The paper contributes to the literature in the areas of models of service quality in student housing management in HIL.

  7. Modeling water quality in an urban river using hydrological factors--data driven approaches.

    Science.gov (United States)

    Chang, Fi-John; Tsai, Yu-Hsuan; Chen, Pin-An; Coynel, Alexandra; Vachaud, Georges

    2015-03-15

    Contrasting seasonal variations occur in river flow and water quality as a result of short duration, severe intensity storms and typhoons in Taiwan. Sudden changes in river flow caused by impending extreme events may impose serious degradation on river water quality and fateful impacts on ecosystems. Water quality is measured in a monthly/quarterly scale, and therefore an estimation of water quality in a daily scale would be of good help for timely river pollution management. This study proposes a systematic analysis scheme (SAS) to assess the spatio-temporal interrelation of water quality in an urban river and construct water quality estimation models using two static and one dynamic artificial neural networks (ANNs) coupled with the Gamma test (GT) based on water quality, hydrological and economic data. The Dahan River basin in Taiwan is the study area. Ammonia nitrogen (NH3-N) is considered as the representative parameter, a correlative indicator in judging the contamination level over the study. Key factors the most closely related to the representative parameter (NH3-N) are extracted by the Gamma test for modeling NH3-N concentration, and as a result, four hydrological factors (discharge, days w/o discharge, water temperature and rainfall) are identified as model inputs. The modeling results demonstrate that the nonlinear autoregressive with exogenous input (NARX) network furnished with recurrent connections can accurately estimate NH3-N concentration with a very high coefficient of efficiency value (0.926) and a low RMSE value (0.386 mg/l). Besides, the NARX network can suitably catch peak values that mainly occur in dry periods (September-April in the study area), which is particularly important to water pollution treatment. The proposed SAS suggests a promising approach to reliably modeling the spatio-temporal NH3-N concentration based solely on hydrological data, without using water quality sampling data. It is worth noticing that such estimation can be

  8. Examining the relationship between service quality and customer satisfaction: a factor specific approach

    OpenAIRE

    Azman Ismail; Ahmad Azan Ridzuan; Nur Ilyani Ranlan Rose; Muhammad Madi Bin Abdullah; Muhammad Sabbir Rahman; Sebastian K. Francis

    2013-01-01

    Purpose: This research was aimed at examining the relationship between service quality and customer satisfaction with data obtained from Malaysian soldiers who were involved in peace keeping missions in a Middle Eastern country. The results of which would enable the management to improve the quality of service accorded to peacekeeping personnel. Design/methodology/approach: The study employed a cross-sectional research design which allowed the researchers to integrate the service quality lite...

  9. Identification and Ranking of Critical Success Factors of Knowledge Management Using Fuzzy Quality Function Deployment Approach: A Case Study

    Directory of Open Access Journals (Sweden)

    Ali Mohaghar

    2014-02-01

    Based on the information accessible for the researchers, this is one of the first works which evaluates the key factors of successful knowledge management through fuzzy quality function deployment approach. It is expected that the proposed method would represent appropriate tools for enterprises which have decided to implement knowledge management because it prioritizes the critical success factors based on the knowledge management outcomes.

  10. Factors Affecting Perceived Learning, Satisfaction, and Quality in the Online MBA: A Structural Equation Modeling Approach

    Science.gov (United States)

    Sebastianelli, Rose; Swift, Caroline; Tamimi, Nabil

    2015-01-01

    The authors examined how six factors related to content and interaction affect students' perceptions of learning, satisfaction, and quality in online master of business administration (MBA) courses. They developed three scale items to measure each factor. Using survey data from MBA students at a private university, the authors estimated structural…

  11. Computation of External Quality Factors for RF Structures by Means of Model Order Reduction and a Perturbation Approach

    CERN Document Server

    Flisgen, Thomas; van Rienen, Ursula

    2016-01-01

    External quality factors are significant quantities to describe losses via waveguide ports in radio frequency resonators. The current contribution presents a novel approach to determine external quality factors by means of a two-step procedure: First, a state-space model for the lossless radio frequency structure is generated and its model order is reduced. Subsequently, a perturbation method is applied on the reduced model so that external losses are accounted for. The advantage of this approach results from the fact that the challenges in dealing with lossy systems are shifted to the reduced order model. This significantly saves computational costs. The present paper provides a short overview on existing methods to compute external quality factors. Then, the novel approach is introduced and validated in terms of accuracy and computational time by means of commercial software.

  12. Examining the relationship between service quality and customer satisfaction: A factor specific approach

    Directory of Open Access Journals (Sweden)

    Azman Ismail

    2013-06-01

    Full Text Available Purpose: This research was aimed at examining the relationship between service quality and customer satisfaction with data obtained from Malaysian soldiers who were involved in peace keeping missions in a Middle Eastern country. The results of which would enable the management to improve the quality of service accorded to peacekeeping personnel. Design/methodology/approach: The study employed a cross-sectional research design which allowed the researchers to integrate the service quality literature, the semi structured interview and the actual survey to collect and examine the data for optimum results. Findings and Originality/value: The outcome of multiple regression analysis showed that responsiveness and assurance variables reflected a high correlation with customer satisfaction. On the other hand, tangibility, reliability and empathy variables recorded an insignificant correlation with customer satisfaction. Research limitations/implications: With respect to practical contributions, the findings of this study can be used as a guideline by the management to improve the quality of peacekeeping in areas of conflict. Practical implications: For security reasons, certain information affecting customer satisfaction could not be examined in detail. Originality/value: This paper presents key results on service quality and customers satisfaction research by looking at the niche segment which was not previously studied from the Malaysian perspective.

  13. Factors associated with the quality of prenatal care: an approach to premature birth

    Directory of Open Access Journals (Sweden)

    Emiliana Cristina Melo

    2015-08-01

    Full Text Available OBJECTIVETo assess the quality of prenatal care in mothers with premature and term births and identify maternal and gestational factors associated with inadequate prenatal care.METHODCross-sectional study collecting data with the pregnant card, hospital records and interviews with mothers living in Maringa-PR. Data were collected from 576 mothers and their born alive infants who were attended in the public service from October 2013 to February 2014, using three different evaluation criteria. The association of prenatal care quality with prematurity was performed by univariate analysis and occurred only at Kessner criteria (CI=1.79;8.02.RESULTSThe indicators that contributed most to the inadequacy of prenatal care were tests of hemoglobin, urine, and fetal presentation. After logistic regression analysis, maternal and gestational variables associated to inadequate prenatal care were combined prenatal (CI=2.93;11.09, non-white skin color (CI=1.11;2.51; unplanned pregnancy (CI=1.34;3.17 and multiparity (CI=1.17;4.03.CONCLUSIONPrenatal care must follow the minimum recommended protocols, more attention is required to black and brown women, multiparous and with unplanned pregnancies to prevent preterm birth and maternal and child morbimortality.

  14. [Factors associated with the quality of prenatal care: an approach to premature birth].

    Science.gov (United States)

    Melo, Emiliana Cristina; Oliveira, Rosana Rosseto de; Mathias, Thais Aidar de Freitas

    2015-08-01

    To assess the quality of prenatal care in mothers with premature and term births and identify maternal and gestational factors associated with inadequate prenatal care. Cross-sectional study collecting data with the pregnant card, hospital records and interviews with mothers living in Maringa-PR. Data were collected from 576 mothers and their born alive infants who were attended in the public service from October 2013 to February 2014, using three different evaluation criteria. The association of prenatal care quality with prematurity was performed by univariate analysis and occurred only at Kessner criteria (CI=1.79;8.02). The indicators that contributed most to the inadequacy of prenatal care were tests of hemoglobin, urine, and fetal presentation. After logistic regression analysis, maternal and gestational variables associated to inadequate prenatal care were combined prenatal (CI=2.93;11.09), non-white skin color (CI=1.11;2.51); unplanned pregnancy (CI=1.34;3.17) and multiparity (CI=1.17;4.03). Prenatal care must follow the minimum recommended protocols, more attention is required to black and brown women, multiparous and with unplanned pregnancies to prevent preterm birth and maternal and child morbimortality.

  15. Integrative Approach to Quality Assessment of Medical Journals Using Impact Factor, Eigenfactor, and Article Influence Scores

    Science.gov (United States)

    Rizkallah, Jacques; Sin, Don D.

    2010-01-01

    Background Impact factor (IF) is a commonly used surrogate for assessing the scientific quality of journals and articles. There is growing discontent in the medical community with the use of this quality assessment tool because of its many inherent limitations. To help address such concerns, Eigenfactor (ES) and Article Influence scores (AIS) have been devised to assess scientific impact of journals. The principal aim was to compare the temporal trends in IF, ES, and AIS on the rank order of leading medical journals over time. Methods The 2001 to 2008 IF, ES, AIS, and number of citable items (CI) of 35 leading medical journals were collected from the Institute of Scientific Information (ISI) and the http://www.eigenfactor.org databases. The journals were ranked based on the published 2008 ES, AIS, and IF scores. Temporal score trends and variations were analyzed. Results In general, the AIS and IF values provided similar rank orders. Using ES values resulted in large changes in the rank orders with higher ranking being assigned to journals that publish a large volume of articles. Since 2001, the IF and AIS of most journals increased significantly; however the ES increased in only 51% of the journals in the analysis. Conversely, 26% of journals experienced a downward trend in their ES, while the rest experienced no significant changes (23%). This discordance between temporal trends in IF and ES was largely driven by temporal changes in the number of CI published by the journals. Conclusion The rank order of medical journals changes depending on whether IF, AIS or ES is used. All of these metrics are sensitive to the number of citable items published by journals. Consumers should thus consider all of these metrics rather than just IF alone in assessing the influence and importance of medical journals in their respective disciplines. PMID:20419115

  16. Wayfinding: a quality factor in human design approach to healthcare facilities.

    Science.gov (United States)

    Del Nord, R

    1999-01-01

    The specific aim of this paper is the systematic analysis of interactions and reciprocal conditions existing between the physical space of hospital buildings and the different categories of individuals that come in contact with them. The physical and environmental facilities of hospital architecture often influence the therapeutic character of space and the employees. If the values of the individual are to be safeguarded in this context, priority needs to be given to such factors as communication, privacy, etc. This would mean the involvement of other professional groups such as psychologists, sociologists, ergonomists, etc. at the hospital building planning stage. This paper will outline the result of some research conducted at the University Research Center "TESIS" of Florence to provide better understanding of design strategies applied to reduce the pathology of spaces within the healthcare environment. The case studies will highlight the parameters and the possible architectural solutions to wayfinding and the humanization of spaces, with particular emphasis on lay-outs, technologies, furniture and finishing design.

  17. Probabilistic prediction of the quality factor of micro-resonator using a stochastic thermo-mechanical multi-scale approach

    OpenAIRE

    Wu, Ling; Lucas, Vincent; Golinval, Jean-Claude; Paquay, Stéphane; Noels, Ludovic

    2016-01-01

    As the size of the device is only one or two orders of magnitude higher than the size of the grains, the structural properties, such as the thermo-elastic quality factor (Q), of micro-electro-mechanical systems (MEMS) made of poly-crystalline materials exhibit a scatter, due to the existing randomness in the grain size, grain orientation, surface roughness... In order to predict the probabilistic behavior of micro-resonators, the authors extend herein a previously developed stochastic 3-...

  18. Factors Affecting Medical Service Quality.

    OpenAIRE

    Ali Mohammad Mosadeghrad

    2014-01-01

    A better understanding of factors influencing quality of medical service can pinpoint better strategies for quality assurance in medical services. This study aimed to identify factors affecting the quality of medical services provided by Iranian physicians.Exploratory in-depth individual interviews were conducted with sixty-four physicians working in various medical institutions in Iran.Individual, organizational and environmental factors enhance or inhibit the quality of medical services. Qu...

  19. Computational fluid dynamics approaches in quality and hygienic production of semisolid low-moisture foods: a review of critical factors.

    Science.gov (United States)

    Mondal, Arpita; Buchanan, Robert L; Lo, Y Martin

    2014-10-01

    Low-moisture foods have been responsible for a number of salmonellosis outbreaks worldwide over the last few decades, with cross contamination from contaminated equipment being the most predominant source. To date, actions have been focused on stringent hygienic practices prior to production, namely periodical sanitization of the processing equipment and lines. Not only does optimum sanitization require in-depth knowledge on the type and source of contaminants, but also the heat resistance of microorganisms is unique and often dependent on the heat transfer characteristics of the low-moisture foods. Rheological properties, including viscosity, degree of turbulence, and flow characteristics (for example, Newtonian or non-Newtonian) of both liquid and semisolid foods are critical factors impacting the flow behavior that consequently interferes heat transfer and related control elements. The demand for progressively more accurate prediction of complex fluid phenomena has called for the employment of computational fluid dynamics (CFD) to model mass and heat transfer during processing of various food products, ranging from drying to baking. With the aim of improving the quality and safety of low-moisture foods, this article critically reviewed the published literature concerning microbial survival in semisolid low-moisture foods, including chocolate, honey, and peanut butter. Critical rheological properties and state-of-the-art CFD application relevant to quality production of those products were also addressed. It is anticipated that adequate prediction of specific transport properties during optimum sanitization through CFD could be used to solve current and future food safety challenges.

  20. Factors Affecting Medical Service Quality

    OpenAIRE

    Mosadeghrad, Ali Mohammad

    2014-01-01

    Abstract Background A better understanding of factors influencing quality of medical service can pinpoint better strategies for quality assurance in medical services. This study aimed to identify factors affecting the quality of medical services provided by Iranian physicians. Methods Exploratory in-depth individual interviews were conducted with sixty-four physicians working in various medical institutions in Iran. Results Individual, organizational and environmental factors enhance or inhib...

  1. Factors Influencing Healthcare Service Quality

    OpenAIRE

    Ali Mohammad Mosadeghrad

    2014-01-01

    Background The main purpose of this study was to identify factors that influence healthcare quality in the Iranian context. Methods Exploratory in-depth individual and focus group interviews were conducted with 222 healthcare stakeholders including healthcare providers, managers, policy-makers, and payers to identify factors affecting the quality of healthcare services provided in Iranian healthcare organisations. Results Quality in healthcare is a production o...

  2. Environmental factors and semen quality

    DEFF Research Database (Denmark)

    Jurewicz, Joanna; Hanke, Wojciech; Radwan, Michal

    2009-01-01

    , trihalomethanes (THMs), mobile phones) on semen quality, by reviewing most recent published literature. MATERIALS AND METHODS: Epidemiological studies focusing on exposure to environmental factors and semen quality for the last ten years were identified by a search of the Pubmed, Medline, Ebsco, Agricola...

  3. Factors Influencing Healthcare Service Quality

    Directory of Open Access Journals (Sweden)

    Ali Mohammad Mosadeghrad

    2014-07-01

    Full Text Available Background The main purpose of this study was to identify factors that influence healthcare quality in the Iranian context. Methods Exploratory in-depth individual and focus group interviews were conducted with 222 healthcare stakeholders including healthcare providers, managers, policy-makers, and payers to identify factors affecting the quality of healthcare services provided in Iranian healthcare organisations. Results Quality in healthcare is a production of cooperation between the patient and the healthcare provider in a supportive environment. Personal factors of the provider and the patient, and factors pertaining to the healthcare organisation, healthcare system, and the broader environment affect healthcare service quality. Healthcare quality can be improved by supportive visionary leadership, proper planning, education and training, availability of resources, effective management of resources, employees and processes, and collaboration and cooperation among providers. Conclusion This article contributes to healthcare theory and practice by developing a conceptual framework that provides policy-makers and managers a practical understanding of factors that affect healthcare service quality.

  4. Factors affecting dental service quality.

    Science.gov (United States)

    Bahadori, Mohammadkarim; Raadabadi, Mehdi; Ravangard, Ramin; Baldacchino, Donia

    2015-01-01

    Measuring dental clinic service quality is the first and most important factor in improving care. The quality provided plays an important role in patient satisfaction. The purpose of this paper is to identify factors affecting dental service quality from the patients' viewpoint. This cross-sectional, descriptive-analytical study was conducted in a dental clinic in Tehran between January and June 2014. A sample of 385 patients was selected from two work shifts using stratified sampling proportional to size and simple random sampling methods. The data were collected, a self-administered questionnaire designed for the purpose of the study, based on the Parasuraman and Zeithaml's model of service quality which consisted of two parts: the patients' demographic characteristics and a 30-item questionnaire to measure the five dimensions of the service quality. The collected data were analysed using SPSS 21.0 and Amos 18.0 through some descriptive statistics such as mean, standard deviation, as well as analytical methods, including confirmatory factor. Results showed that the correlation coefficients for all dimensions were higher than 0.5. In this model, assurance (regression weight=0.99) and tangibility (regression weight=0.86) had, respectively, the highest and lowest effects on dental service quality. The Parasuraman and Zeithaml's model is suitable to measure quality in dental services. The variables related to dental services quality have been made according to the model. This is a pioneering study that uses Parasuraman and Zeithaml's model and CFA in a dental setting. This study provides useful insights and guidance for dental service quality assurance.

  5. Factor selection for service quality evaluation: a hospital case study.

    Science.gov (United States)

    Ameryoun, Ahmad; Najafi, Seyedvahid; Nejati-Zarnaqi, Bayram; Khalilifar, Seyed Omid; Ajam, Mahdi; Ansarimoghadam, Ahmad

    2017-02-13

    Purpose The purpose of this paper is to develop a systematic approach to predict service quality dimension's influence on service quality using a novel analysis based on data envelopment and SERVQUAL. Design/methodology/approach To assess hospital service quality in Tehran, expectation and perception of those who received the services were evaluated using SERVQUAL. The hospital service quality dimensions were found by exploratory factor analysis (EFA). To compare customer expectation and perception, perceived service quality index (PSQI) was measured using a new method based on common weights. A novel sensitivity approach was used to test the service quality factor's impact on the PSQI. Findings A new service quality dimension named "trust in services" was found using EFA, which is not an original SERVQUAL factor. The approach was applied to assess the hospital's service quality. Since the PSQI value was 0.76 it showed that improvements are needed to meet customer expectations. The results showed the factor order that affect PSQI. "Trust in services" has the strongest influence on PSQI followed by "tangibles," "assurance," "empathy," and "responsiveness," respectively. Practical implications This work gives managers insight into service quality by following a systematic method; i.e., measuring perceived service quality from the customer viewpoint and service factors' impact on customer perception. Originality/value The procedure helps managers to select the required service quality dimensions which need improvement and predict their effects on customer perception.

  6. Product quality as a key factor of the enterprise competitiveness

    Directory of Open Access Journals (Sweden)

    Oksana Bilan

    2014-11-01

    Full Text Available The main approaches to the definition of the category "product quality" are considered in the article. The definition of product quality as the set of characteristics that reflect the necessary consumer properties of products are formulated by the author. The factors of forming of the products quality are analysed, advantages that will be got by an enterprise from improving product quality and factors that stimulate or restrain this process are defined. Main reasons of objective necessity to increase the level of quality of products (services and realization of management and providing of necessary products quality based on a continuous cycle are distinguished. Directions of improvement of product quality due to the certification of the quality management system of an enterprise in accordance with ISO 9001, improvement of raw materials quality, improvement of material and technical support of production, improvement of labour quality, the orientation of the enterprise on consumer demand and quality control are suggested

  7. Impact on quality culture of total quality management practices factors

    Directory of Open Access Journals (Sweden)

    Faihan Mosaad Saud Alotaibi

    2014-09-01

    Full Text Available This study investigated total quality management practices and quality culture of Saudi Arabian contractors. Improving the quality can be achieved through implementation of total quality management although studies and researches work regarding this improvement is still lacking. A quantitative approach using the survey method was employed. With assistance from the Saudi Arabia Ministry of Municipal and Rural Affairs, survey questionnaires were distributed to selected contractors in Saudi Arabia. The collected data were analysed using correlation, and multiple regression analyses. The key findings were the confirmation of significant relationships between all total quality management practices and quality culture and a positive relationship between quality management practices and quality culture. Furthermore, total quality management practices were found to be able to explain 68.1% of the variance in quality culture, while quality culture explained 12.5% of the variance in competitiveness. Quality culture was found to only partially mediate the relationship between total quality management practices and competitiveness.

  8. An Approach towards Software Quality Assessment

    Science.gov (United States)

    Srivastava, Praveen Ranjan; Kumar, Krishan

    Software engineer needs to determine the real purpose of the software, which is a prime point to keep in mind: The customer’s needs come first, and they include particular levels of quality, not just functionality. Thus, the software engineer has a responsibility to elicit quality requirements that may not even be explicit at the outset and to discuss their importance and the difficulty of attaining them. All processes associated with software quality (e.g. building, checking, improving quality) will be designed with these in mind and carry costs based on the design. Therefore, it is important to have in mind some of the possible attributes of quality. We start by identifying the metrics and measurement approaches that can be used to assess the quality of software product. Most of them can be measured subjectively because there is no solid statistics regarding them. Here, in this paper we propose an approach to measure the software quality statistically.

  9. APPROACHES TO QUALITY OF LIFE ANALYSISQUANTICATION

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    Larisa E. Danilina

    2015-01-01

    Full Text Available The paper reviews different approaches to quality of life measurement used in Russian and international statistics. It outlines the essence of J. Stiglitz’s recommendations on development of quality of life statistical indicators, analyses proposals and practical application of innovative approaches of quality of life measurement by the French National Institute for Statistics and Economic Studies (INSEE. The paper reviews Rosstat’s (Russian Federal State Statistics Service new research as well as an independent research in the area of quality of life research. The authors make proposals to extend the list of aspects analyzed an quality of life research and underline the importance of such a review through regional specifics. They suggest extending the system of quality of life statistical indicators by certain coefficients characterizing economic development disparity and its influence on the quality of life.

  10. Impact on quality culture of total quality management practices factors

    OpenAIRE

    Faihan Mosaad Saud Alotaibi

    2014-01-01

    This study investigated total quality management practices and quality culture of Saudi Arabian contractors. Improving the quality can be achieved through implementation of total quality management although studies and researches work regarding this improvement is still lacking. A quantitative approach using the survey method was employed. With assistance from the Saudi Arabia Ministry of Municipal and Rural Affairs, survey questionnaires were distributed to selected contractors i...

  11. APPROACHES TO QUALITY MANAGEMENT AT EUROPEAN LEVEL

    Directory of Open Access Journals (Sweden)

    Salagean Horatiu Catalin

    2013-07-01

    Full Text Available In the current economic context, quality has become a source of competitive advantage and organizations must perceive quality as something natural and human in order to achieve excellence. The proper question for the context of the internationalisation of the economy is whether the culture of the regions, states or nations affects the development in the quality management field and the quality approach. The present study tries to give a theoretical approach of how culture influences the quality approach at the European level. The study deals only with the European quality approach, beacuse at European level one could meet a great variety of models and methodologies. In the U.S.A. and Japan one could identify a specific cultural approach regarding quality. At the European level, we cannot discuss in the same terms, because each country has a different cultural specifics in terms of quality. In order to determine the cultural specificity of the countries surveyed, the study has used the most popular analysis tool of cultural dimensions, namely the Dutch Professor Geert Hofstede\\'s model. The model illustrates according to a survey, the organizational behavior of several countries and was able to identify a set of variables and fundamental dimensions, that differentiates one culture from another. An attempt was made to see if there are connections between the values of Hofestede \\'s cultural dimensions and the quality characteristics in the analysed countries. The study, describes on the one hand,the quality evolution from quality control to Total Quality Management and on the other hand, focuses on the quality approach modalities at European level. The second part of the paper is structured into two parts, addressing on the one hand the quality in countries of Western Europe, such as United Kingdom, France and Germany,because these three countries are considered to be the exponents of quality development in Western Europe. In the same time, the

  12. Quality Control Approaches for Chinese Herbal Medicines

    Institute of Scientific and Technical Information of China (English)

    YUAN Hai-long; ZHANG Tian-tian; XIAO Xiao-he

    2011-01-01

    The current official quality control approaches meet the challenges from the complexity of herbal medicines.In fact,any herbal medicines containing numerous unknown components,its curative effect usually depends on the whole of herbal medicines,so it is impossible and unnecessary to qualitatively and quantitatively study every component.By investigating the limitations of current quality control approaches for herbal medicines and the difference and similarity in the chemical substantial style as well as quality control pattern of herbal medicines,a new quality control approach for Chinese herbal medicines should be explored and designed.The combination approach of chemical analysis with bioassay is promising to be developed and employed in order to ensure the safety and efficacy of Chinese herbal medicines.

  13. Healthcare Professionals’ Perception and Related Factors About Total Quality Management

    OpenAIRE

    Tapan, Birkan; ALICI, Selin; GAYEF, Albena; YILDIRIM, Nurdan; Sezen, Adem

    2015-01-01

    Quality defined as extent of features of any product or service to meet expectations of consumers enjoying such product or service. Although it was a concept first emerged in manufacturing industry, today, it has become an important competitive factor for service institutions as well. Total Quality Management approach is drawing more and more interest as international borders start to fade out in parallel with globalization and increasing competition. Total Quality Management is a ma...

  14. Scaling up the Quality of Care Approach

    Institute of Scientific and Technical Information of China (English)

    XieZhenming

    2005-01-01

    Like the pilot project, the scaling up of the quality of care approach is also new in China and requires continued research anct explorauon, in July 2003, the National Population and Family Planning Commission (NPFPC) drew on the experience of scaling up the quality of care project and decided to launch a campaign to select and commend model counties (cities/districts) in implementing the project in order to set an example for different regions with different economies and ensure the quality of care approach is adequately applied.

  15. Biophysics of NASA radiation quality factors.

    Science.gov (United States)

    Cucinotta, Francis A

    2015-09-01

    NASA has implemented new radiation quality factors (QFs) for projecting cancer risks from space radiation exposures to astronauts. The NASA QFs are based on particle track structure concepts with parameters derived from available radiobiology data, and NASA introduces distinct QFs for solid cancer and leukaemia risk estimates. The NASA model was reviewed by the US National Research Council and approved for use by NASA for risk assessment for International Space Station missions and trade studies of future exploration missions to Mars and other destinations. A key feature of the NASA QFs is to represent the uncertainty in the QF assessments and evaluate the importance of the QF uncertainty to overall uncertainties in cancer risk projections. In this article, the biophysical basis for the probability distribution functions representing QF uncertainties was reviewed, and approaches needed to reduce uncertainties were discussed. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  16. A data-driven approach to quality risk management

    Directory of Open Access Journals (Sweden)

    Demissie Alemayehu

    2013-01-01

    Full Text Available Aim: An effective clinical trial strategy to ensure patient safety as well as trial quality and efficiency involves an integrated approach, including prospective identification of risk factors, mitigation of the risks through proper study design and execution, and assessment of quality metrics in real-time. Such an integrated quality management plan may also be enhanced by using data-driven techniques to identify risk factors that are most relevant in predicting quality issues associated with a trial. In this paper, we illustrate such an approach using data collected from actual clinical trials. Materials and Methods: Several statistical methods were employed, including the Wilcoxon rank-sum test and logistic regression, to identify the presence of association between risk factors and the occurrence of quality issues, applied to data on quality of clinical trials sponsored by Pfizer. Results: Only a subset of the risk factors had a significant association with quality issues, and included: Whether study used Placebo, whether an agent was a biologic, unusual packaging label, complex dosing, and over 25 planned procedures. Conclusion: Proper implementation of the strategy can help to optimize resource utilization without compromising trial integrity and patient safety.

  17. EVALUATION OF PROGNOSTIC FACTORS IN QUALITY OF LIFE OF PATIENTS WITH ADOLESCENT IDIOPATHIC SCOLIOSIS UNDERGOING SPINAL FUSION BY THE POSTERIOR APPROACH

    Directory of Open Access Journals (Sweden)

    FELIPE DE MORAES POMAR

    Full Text Available ABSTRACT Objective: To evaluate the prognostic factors in the treatment of patients diagnosed with adolescent idiopathic scoliosis undergoing spinal fusion by the posterior approach. Methods: The study included 48 patients with idiopathic adolescent scoliosis (43 females and 5 males who underwent spinal fusion by the posterior approach, with an average age at diagnosis of 12 years, and clinical signs of Risser between 3 and 4 at the time of surgery. Clinical and radiographic measurements were performed, the participants answered the SRS-30 questionnaire, and the analysis of the medical record data was performed in two occasions during the preoperative period and at the end of two years of follow-up. Results: All satisfaction measures showed statistically significant change after the procedure (p<0.05 with respect to the radiographic characteristics, except for the lumbar apical vertebral translation (p=0.540 and Cobb L1-L5 (p=0.225. Conclusion: In general, it was found that patients who received surgical treatment were more satisfied with their appearance than those who underwent conservative treatment.

  18. Quality factors to consider in condensate selection

    Energy Technology Data Exchange (ETDEWEB)

    Lywood, B. [Crude Quality Inc., Edmonton, AB (Canada)

    2009-07-01

    Many factors must be considered when assessing the feasibility of using condensates as a diluent for bitumen or heavy crude production blending. In addition to commercial issues, the effect of condensate quality is a key consideration. In general, condensate quality refers to density and viscosity. However, valuation decisions could be enhanced through the expansion of quality definitions and understanding. This presentation focused on the parameters that are important in choosing a diluent grade product. It also reviewed pipeline and industry specifications and provided additional information regarding general properties for bitumen and condensate compatibility; sampling and quality testing needs; and existing sources of information regarding condensate quality. tabs., figs.

  19. Quality factor of aberrated gaussian laser beams

    CSIR Research Space (South Africa)

    Mafusire, C

    2010-09-01

    Full Text Available A model is used to calculate the beam quality factor of a laser beam from Zernike coefficients. It is tested by programming aberration coefficients on a laser beam and measuring the beam quality using a Shack-Hartmann wavefront sensor. The two show...

  20. A quality by design approach for longitudinal quality attributes.

    Science.gov (United States)

    Lebrun, Pierre; Giacoletti, Katherine; Scherder, Tara; Rozet, Eric; Boulanger, Bruno

    2015-01-01

    The concept of quality by design (QbD) as published in ICH-Q8 is currently one of the most recurrent topics in the pharmaceutical literature. This guideline recommends the use of information and prior knowledge gathered during pharmaceutical development studies to provide a scientific rationale for the manufacturing process of a product and provide guarantee of future quality. This poses several challenges from a statistical standpoint and requires a shift in paradigm from traditional statistical practices. First, to provide "assurance of quality" of future lots implies the need to make predictions regarding the quality given past evidence and data. Second, the quality attributes described in the Q8 guidelines are not always a set of unique, independent measurements. In many cases, these criteria are complicated longitudinal data with successive acceptance criteria over a defined period of time. A common example is a dissolution profile for a modified or extended-release solid dosage form that must fall within acceptance limits at several time points. A Bayesian approach for longitudinal data obtained in various conditions of a design of experiment is provided to elegantly address the ICH-Q8 recommendation to provide assurance of quality and derive a scientifically sound design space.

  1. Success Factors for Quality in Product Development

    OpenAIRE

    Sajjan, Dev; Petersson, Henrik

    2014-01-01

    Background: Today’s fast-paced product development cycles and increasing complexity of automotive products require new processes, methods and tools to manage product development organizations. Besides that, reduced cost and higher product quality calls for increased product development effectiveness and efficiency since product development stands for significant part of the quality costs. This implies a need for holistic approach by sharing and creating new knowledge and faster problem solvin...

  2. Factors Influencing the Quality of Mobile Applications

    Directory of Open Access Journals (Sweden)

    Alin ZAMFIROIU

    2014-01-01

    Full Text Available Mobile applications are becoming increasingly used. Mobile devices are becoming indispensable for the user. In the material are claiming the sales of mobile devices internationally and the use of mobile applications compared to traditional internet use on desktop systems for the United States. Are presented influences the quality of mobile applications and based on these influencing factors built a model of choice for optimal application of mobile applications and traditional desktop application. At the end of the material presented methods to increase quality by tracking the influence factors during the development of mobile applications.

  3. Quality factor concept in piezoceramic transformer performance description.

    Science.gov (United States)

    Mezheritsky, Alex V

    2006-02-01

    A new general approach based on the quality factor concept to piezoceramic transformer (PT) performance description is proposed. The system's quality factor, material elastic anisotropy, and coupling factors of the input and output sections of an electrically excited and electrically loaded PT fully characterize its resonance and near-resonance behavior. The PT efficiency, transformation ratio, and input and output power were analytically analyzed and simulated as functions of the load and frequency for the simplest classical Langevin-type and Rosen-type PT designs. A new formulation of the electrical input impedance allows one to separate the power consumed by PT from the power transferred into the load. The system's PT quality factor takes into account losses in each PT "input-output-load" functional components. The loading process is changing PT input electrical impedance on the way that under loading the minimum series impedance is increasing and the maximum parallel impedance is decreasing coincidentally. The quality-factors ratio, between the states of fully loaded and nonloaded PT, is one of the best measures of PTs dynamic performance--practically, the lower the ratio is, the better PT efficiency. A simple and effective method for the loaded PT quality factor determination is proposed. As was found, a piezoceramic with low piezoelectric anisotropy is required to provide maximum PT efficiency and higher corresponding voltage gain. Limitations on the PT output voltage and power, caused by nonlinear effects in piezoceramics, were established.

  4. Factors that Predict Quality Classroom Technology Use

    Science.gov (United States)

    Hastings, Tricia A.

    2009-01-01

    Despite technological advancements intended to enhance teaching and learning in the 21st century, numerous teacher and school factors continue to impede quality classroom technology use. Determining the effectiveness of educational technology is challenging and requires a detailed understanding of multifaceted, complex, contextual relationships.…

  5. Factors that Predict Quality Classroom Technology Use

    Science.gov (United States)

    Hastings, Tricia A.

    2009-01-01

    Despite technological advancements intended to enhance teaching and learning in the 21st century, numerous teacher and school factors continue to impede quality classroom technology use. Determining the effectiveness of educational technology is challenging and requires a detailed understanding of multifaceted, complex, contextual relationships.…

  6. Theoretical Aspects and Methodological Approaches to Sales Services Quality Assessment

    Directory of Open Access Journals (Sweden)

    Tarasova EE

    2015-11-01

    Full Text Available The article defines trade service quality and proposes an object-oriented approach for its essence interpretation, according to which such components as product offering and goods quality, service forms and goods selling methods, merchandising, services and staff are singled out; a model of managing retail outlets trading service, which covers levels of strategic, tactical and operational management and is aimed at ensuring customers’ perception expectations, achieving sustainable competitive positions and increasing customers’ loyalty is worked out; a methodology of trade services quality estimation that allows to carry out a comparative assessment of cooperative retailing both in terms of general indicators and their individual components, regulate the factors affecting trade services quality and have a positive administrative action is developed and tested; the results of evaluation of the customers’ service quality in the consumer cooperative retailers, dynamics of overall and comprehensive indicators of measurement of trade service quality for selected components are given; the main directions and measures for improving trade services quality basing on quantitative values of individual indicators for each of the five selected components (product offering and goods quality, service forms and sale methods, merchandising, services, staff are stated.

  7. High quality factor indium oxide mechanical microresonators

    Energy Technology Data Exchange (ETDEWEB)

    Bartolomé, Javier, E-mail: j.bartolome@fis.ucm.es; Cremades, Ana; Piqueras, Javier [Department of Materials Physics, Faculty of Physics, Universidad Complutense de Madrid, 28040 Madrid (Spain)

    2015-11-09

    The mechanical resonance behavior of as-grown In{sub 2}O{sub 3} microrods has been studied in this work by in-situ scanning electron microscopy (SEM) electrically induced mechanical oscillations. Indium oxide microrods grown by a vapor–solid method are naturally clamped to an aluminum oxide ceramic substrate, showing a high quality factor due to reduced energy losses during mechanical vibrations. Quality factors of more than 10{sup 5} and minimum detectable forces of the order of 10{sup −16} N/Hz{sup 1/2} demonstrate their potential as mechanical microresonators for real applications. Measurements at low-vacuum using the SEM environmental operation mode were performed to study the effect of extrinsic damping on the resonators behavior. The damping coefficient has been determined as a function of pressure.

  8. A participatory sensing approach to characterize ride quality

    Science.gov (United States)

    Bridgelall, Raj

    2014-03-01

    Rough roads increase vehicle operation and road maintenance costs. Consequently, transportation agencies spend a significant portion of their budgets on ride-quality characterization to forecast maintenance needs. The ubiquity of smartphones and social media, and the emergence of a connected vehicle environment present lucrative opportunities for cost-reduction and continuous, network-wide, ride-quality characterization. However, there is a lack of models to transform inertial and position information from voluminous data flows into indices that transportation agencies currently use. This work expands on theories of the Road Impact Factor introduced in previous research. The index characterizes road roughness by aggregating connected vehicle data and reporting roughness in direct proportion to the International Roughness Index. Their theoretical relationships are developed, and a case study is presented to compare the relative data quality from an inertial profiler and a regular passenger vehicle. Results demonstrate that the approach is a viable alternative to existing models that require substantially more resources and provide less network coverage. One significant benefit of the participatory sensing approach is that transportation agencies can monitor all network facilities continuously to locate distress symptoms, such as frost heaves, that appear and disappear between ride assessment cycles. Another benefit of the approach is continuous monitoring of all high-risk intersections such as rail grade crossings to better understand the relationship between ride-quality and traffic safety.

  9. Factors influencing quality of life in asthmatics

    DEFF Research Database (Denmark)

    Al-kalemji, Abir; Petersen, Karin Dam; Sørensen, Jan

    2013-01-01

    INTRODUCTION: The quality of life (QOL) in persons with asthma is reduced and different factors such as demography, asthma severity and psychiatric comorbidity play an influential role. However, little is known about the interplay of these factors. OBJECTIVE: To describe QOL in relation to asthma...... and analyse for the relative impact of asthma severity, psychiatric comorbidity, lifestyle (smoking and obesity) and demographic determinants on QOL in persons with asthma. METHODS: One thousand one hundred sixty-one subjects from an earlier cohort with and without asthma were sent an asthma screening...... gender and smoking were associated with reduced QOL, suggesting that these factors play an independent role on lowering QOL. Depression did not inflate the relationship between asthma severity and worse QOL, suggesting that asthma severity plays an independent role on everyday life regardless...

  10. Software quality engineering a practitioner's approach

    CERN Document Server

    Suryn, Witold

    2014-01-01

    Software quality stems from two distinctive, but associated, topics in software engineering: software functional quality and software structural quality. Software Quality Engineering studies the tenets of both of these notions, which focus on the efficiency and value of a design, respectively. The text addresses engineering quality on both the application and system levels with attention to Information Systems and Embedded Systems as well as recent developments. Targeted at graduate engineering students and software quality specialists, the book analyzes the relationship between functionality

  11. Process Approach to Cost of Quality

    Directory of Open Access Journals (Sweden)

    Katarzyna Szczepańska

    2009-12-01

    Full Text Available Contemporary understanding comprehending cost of quality is connected both with the sphere of the management, as well as the operational activity. Borders of considering the category of quality costs moved beyond the technical – technological area. Trial including costs let the quality for classifying them with reference to all action carried out in the modern enterprise. Standard models of quality costs and the activity – based costing appointed new prospects of economics of the quality in the business administration.

  12. Influence of Price and Quality to Customer Satisfaction: Neuromarketing Approach

    Directory of Open Access Journals (Sweden)

    Aurimas Dapkevičius

    2011-04-01

    Full Text Available The purpose of this article is to analyze literature and find out empirical evidence on product price and quality influence on customer satisfaction through neuromarketing approach. Customers’ satisfaction on their purchase is a significant factor that leads business to success. In recent times, customer satisfaction has gained new attention within the context of the paradigm shift from transactional marketing to relationship marketing. Even it is agreed in the literature that price and quality has high effect on customer satisfaction; still there is little empirical evidence exploring this relation. Almost nothing is known about the human neural mechanisms through which it affects the decisions made by individuals. So, in this article there are reviewed two neuromarketing study cases as neuromarketing provides qualitatively different information, ostensibly better quality comparing to that obtained by traditional methods. The whole article reveals that price and quality is an important factor for customer satisfaction which leads to marketing managers’ decisions complexity nowadays as markets are becoming more and more complex and overloaded.Article in English

  13. Identifying key hospital service quality factors in online health communities.

    Science.gov (United States)

    Jung, Yuchul; Hur, Cinyoung; Jung, Dain; Kim, Minki

    2015-04-07

    The volume of health-related user-created content, especially hospital-related questions and answers in online health communities, has rapidly increased. Patients and caregivers participate in online community activities to share their experiences, exchange information, and ask about recommended or discredited hospitals. However, there is little research on how to identify hospital service quality automatically from the online communities. In the past, in-depth analysis of hospitals has used random sampling surveys. However, such surveys are becoming impractical owing to the rapidly increasing volume of online data and the diverse analysis requirements of related stakeholders. As a solution for utilizing large-scale health-related information, we propose a novel approach to identify hospital service quality factors and overtime trends automatically from online health communities, especially hospital-related questions and answers. We defined social media-based key quality factors for hospitals. In addition, we developed text mining techniques to detect such factors that frequently occur in online health communities. After detecting these factors that represent qualitative aspects of hospitals, we applied a sentiment analysis to recognize the types of recommendations in messages posted within online health communities. Korea's two biggest online portals were used to test the effectiveness of detection of social media-based key quality factors for hospitals. To evaluate the proposed text mining techniques, we performed manual evaluations on the extraction and classification results, such as hospital name, service quality factors, and recommendation types using a random sample of messages (ie, 5.44% (9450/173,748) of the total messages). Service quality factor detection and hospital name extraction achieved average F1 scores of 91% and 78%, respectively. In terms of recommendation classification, performance (ie, precision) is 78% on average. Extraction and

  14. Quality Assurance in Post-Secondary Education: Some Common Approaches

    Science.gov (United States)

    Law, Dennis Chung Sea

    2010-01-01

    Purpose: The common approaches to quality assurance (QA), as practiced by most post-secondary education institutions for internal quality monitoring and most QA authorities for external quality monitoring (EQM), have been considered by many researchers as having largely failed to address the essence of educational quality. The purpose of this…

  15. Quality Assurance in Post-Secondary Education: Some Common Approaches

    Science.gov (United States)

    Law, Dennis Chung Sea

    2010-01-01

    Purpose: The common approaches to quality assurance (QA), as practiced by most post-secondary education institutions for internal quality monitoring and most QA authorities for external quality monitoring (EQM), have been considered by many researchers as having largely failed to address the essence of educational quality. The purpose of this…

  16. APPROACH TO QUALITY ASSURANCE IN HIGHER EDUCATION

    Directory of Open Access Journals (Sweden)

    Zora Arsovski

    2007-03-01

    Full Text Available Quality assurance in higher education is streamed in two interconnected concepts: (1 quality management according to ISO 9000 and (2 Bologna process. In this paper both concepts are presented, with point on internal state and term plan activities for quality improvement in higher education in Serbia.

  17. Design optimization for cost and quality: The robust design approach

    Science.gov (United States)

    Unal, Resit

    1990-01-01

    Designing reliable, low cost, and operable space systems has become the key to future space operations. Designing high quality space systems at low cost is an economic and technological challenge to the designer. A systematic and efficient way to meet this challenge is a new method of design optimization for performance, quality, and cost, called Robust Design. Robust Design is an approach for design optimization. It consists of: making system performance insensitive to material and subsystem variation, thus allowing the use of less costly materials and components; making designs less sensitive to the variations in the operating environment, thus improving reliability and reducing operating costs; and using a new structured development process so that engineering time is used most productively. The objective in Robust Design is to select the best combination of controllable design parameters so that the system is most robust to uncontrollable noise factors. The robust design methodology uses a mathematical tool called an orthogonal array, from design of experiments theory, to study a large number of decision variables with a significantly small number of experiments. Robust design also uses a statistical measure of performance, called a signal-to-noise ratio, from electrical control theory, to evaluate the level of performance and the effect of noise factors. The purpose is to investigate the Robust Design methodology for improving quality and cost, demonstrate its application by the use of an example, and suggest its use as an integral part of space system design process.

  18. A Framework to Measure the Service Quality of Distributor with Fuzzy Graph Theoretic Approach

    Directory of Open Access Journals (Sweden)

    Tarun Kumar Gupta

    2016-01-01

    Full Text Available A combination of fuzzy logic and graph theoretic approach has been used to find the service quality of distributor in a manufacturing supply chain management. This combination is termed as the fuzzy graph theoretic (FGT approach. Initially the identified factors were grouped by SPSS (statistical package for social science software and then the digraph approach was applied. The interaction and inheritance values were calculated by fuzzy graph theory approach in terms of permanent function. Then a single numerical index was calculated by using permanent function which indicates the distributor service quality. This method can be used to compare the service quality of different distributors.

  19. QUALITY APPROACHES AND INTERVENTIONS IN GREEKSECONDARY EDUCATION

    Directory of Open Access Journals (Sweden)

    H. Prokopiou

    2007-12-01

    Full Text Available The present paper is focused on the application of quality principles in Greek Secondary Education and comprises of two interrelated parts. In the first part of this work definitions, a theoretical framework and multimodels of quality in education are introduced and discussed, in brief. Next, the initiatives applied for improving the quality of education are emphasized. Since 1996 and for more than a decade, a series of ESF interventions have been applied in Greece with measurable impact on improving the quality of Greek Secondary Education. The most important policy measures focused at Secondary Education together with their results are presented in the second part of the paper.

  20. A Review on quality by design approach (QBD for Pharmaceuticals

    Directory of Open Access Journals (Sweden)

    Vemuri Pavan Kumar

    2015-03-01

    Full Text Available Quality by Design is the modern approach for quality of pharmaceuticals. It describes use of Quality by Design to ensure quality of Pharmaceuticals. In this review, the Quality by Design is described and some of its elements identified. Process parameters and quality attributes are identified for each unit operation. Benefits, opportunities and steps involved in Quality by Design of Pharmaceutical products are described. It is based on the ICH Guidelines Q8 for pharmaceutical development, Q9 for quality risk management, Q10 for pharmaceutical quality systems. It also gives application of Quality by Design in pharmaceutical development and manufacturing of pharmaceuticals. The aim of the pharmaceutical development is to design a quality product and its manufacturing process to consistently deliver the intended performance of the product. Quality cannot be tested into products but quality should be built in by design. It includes the Quality target product profile, critical quality attributes and key aspects of Quality by Design. It also gives comparison between product quality by end product testing and product quality by Quality by Design. The foundation of Quality by Design is ICH Guidelines.

  1. Stored electromagnetic energy and quality factor of radiating structures

    Science.gov (United States)

    Capek, Miloslav; Jelinek, Lukas; Vandenbosch, Guy A. E.

    2016-04-01

    This paper deals with the old yet unsolved problem of defining and evaluating the stored electromagnetic energy-a quantity essential for calculating the quality factor, which reflects the intrinsic bandwidth of the considered electromagnetic system. A novel paradigm is proposed to determine the stored energy in the time domain leading to the method, which exhibits positive semi-definiteness and coordinate independence, i.e. two key properties actually not met by the contemporary approaches. The proposed technique is compared with an up-to-date frequency domain method that is extensively used in practice. Both concepts are discussed and compared on the basis of examples of varying complexity.

  2. EIA's approach to information quality

    Energy Technology Data Exchange (ETDEWEB)

    Freedman, S.R. (Energy Information Administration, Washington, DC (United States))

    1993-01-01

    EIA has evolved a unique approach to improving information quality in a decentralized statistical agency. The idea is to give the program offices full line responsibility for the quality of their products, but to rely on a quality assurance group to oversee their efforts. The quality assurance group assures that these efforts are effective through a systematic process of data and model evaluation, applied research to address technical problems, and administrative procedures and standards to promote improved practice. Together the program offices and the quality assurance group keep the agency's leadership fully appriased of quality concerns and actively involved in solving quality problems. After reviewing the overall approach, this article describes the kinds of evaluations that are done and the mix of administrative procedures and standards used to accomplish changes. The article concludes with a discussion of the kinds of problems that are amenable to this approach.

  3. A NEW APPROACH TO QUALITY ENHANCEMENT: A CASE STUDY

    Directory of Open Access Journals (Sweden)

    Slavko Arsovski

    2011-12-01

    Full Text Available There are a number of approaches for quality improvement that start from previously defined goal and definition of activities which lead to achievement of that goal. In this deterministic approach, risk in quality improvement has constantly been reduced by improvement activities, with relatively little increase in goal function. The basic approach is presented in the paper as well as measures and activities for decease of risk and vulnerability of quality improvement. This approach is tested in large company and part of results of model testing is presented in this paper.

  4. Approaches to quality management in hotel industry

    Directory of Open Access Journals (Sweden)

    Kateřina Ryglová

    2013-01-01

    Full Text Available The aim of the paper is to present possibilities and specifics of quality management in hotel services with the focus on the Servqual model. Servqual works on the definition of five dimensions of service quality: tangibles, reliability, responsiveness, assurance and empathy. Demonstrating the practical application of Servqual in selected hotels in the Czech Republic is also a part of the paper. Input data have been gained by force of a primary field-research with the help of a quantitative research via questionnaires and deep interviews. The results of the Servqual score for individual dimensions of service quality have also been used to calculate a total weighted score for the examined hotels and to outline benchmarking utilisation possibilities.

  5. Statistical quality control a loss minimization approach

    CERN Document Server

    Trietsch, Dan

    1999-01-01

    While many books on quality espouse the Taguchi loss function, they do not examine its impact on statistical quality control (SQC). But using the Taguchi loss function sheds new light on questions relating to SQC and calls for some changes. This book covers SQC in a way that conforms with the need to minimize loss. Subjects often not covered elsewhere include: (i) measurements, (ii) determining how many points to sample to obtain reliable control charts (for which purpose a new graphic tool, diffidence charts, is introduced), (iii) the connection between process capability and tolerances, (iv)

  6. Total quality approach at ABB Atom Nuclear Fuel - winner of the Swedish quality award 1994

    Energy Technology Data Exchange (ETDEWEB)

    Moorlin, K.; Olsson, S. [ABB Atom AB, Vaesteraas (Sweden)

    1995-12-31

    ABB Atom Nuclear Fuel Division received the Swedish Quality Award 1994. The company has since many years a reputation for high product quality and a well implemented quality assurance system. Since some years a total quality approach is applied. For ABB Atom, total quality means continuous improvement of all business processes keeping the customer in focus. This paper elaborates on the improvement tools used at the ABB Atom Nuclear Fuel Division and gives some detailed information of the experience. (author) 6 figs.

  7. Quality systems in health care: A sociotechnical approach

    NARCIS (Netherlands)

    P.P.M. Harteloh (Peter)

    2003-01-01

    textabstractIn this paper, we explore a sociotechnical approach to construct quality systems as an alternative to the traditional, ISO orientated approach. A sociotechnical approach is characterised as bottom-up, incremental, information technology facilitated and indicator driven. Its purpose is to

  8. Process Approach to Determining Quality Inspection Deployment

    Science.gov (United States)

    2015-06-08

    International Organization for Standardization, Switzerland , 2005. 4. Montgomery, D.C., Statistical Quality Control. John Wiley and Sons, Hoboken, New Jersey...set, yet they can be changed by the user. However, if they are changed, the tool will flag this change as a risk to the correctness of the conclusion...complete the study. Note that the weights are set, yet can be changed by the user. However, if they are changed, the tool will flag this change as a risk

  9. Quality Management System according to the family of Cuban Standards ISO 9000 CN Total Quality approach.

    Directory of Open Access Journals (Sweden)

    Leonel C. Alfaro Pérez

    2009-12-01

    Full Text Available In this article we develop some considerations and suggestions for organizations in Cuba who want to design and implement systems with Quality Management Total Quality approach to the family of Cuban Standards ISO 9000 CN. It makes a comparative analysis between what is a System of Quality Management, Total Quality and the European model of quality management, detailing the similarities and differences, which allow us to understand how systems can be designed and managed focuses on Total Quality. It describes in a coherent way the main activities of a quality management system which can not be absent in its design and subsequent management.

  10. Learning approaches and studies of effect of environmental factors

    Directory of Open Access Journals (Sweden)

    Mirkov Snežana

    2009-01-01

    Full Text Available There is a presentation of 3P model of learning (Presage-Process-Product, which comprises learning approaches placed in a wider context of the set of variables related to personality, environment, process and outcomes of learning. Three approaches to learning - surface, deep and achievement-oriented - consist of motives and the corresponding learning strategies. There is a discussion of the findings and implications of a great deal of research using the instruments based on this model. We analyzed research findings about the effect of instruction on learning approaches acquired by pupils, and especially students. It is shown how based on learning approach employed by pupils it is possible to draw conclusions about the quality of instruction. Testing the instruments on various samples indicates that the model is applicable in different cultures. Cross-cultural research opened up the problem of relation between memorising and understanding. Further research is necessary, both empirical and theoretical, that is, development of conceptualization of these constructs, and especially their role in education. Perspectives for further research also open up in the direction of studying various factors connected with personality and their relations with learning approaches. The role of learning approaches of teachers in developing the learning approaches of pupils is yet to be examined.

  11. Standardized approach for developing probabilistic exposure factor distributions

    Energy Technology Data Exchange (ETDEWEB)

    Maddalena, Randy L.; McKone, Thomas E.; Sohn, Michael D.

    2003-03-01

    The effectiveness of a probabilistic risk assessment (PRA) depends critically on the quality of input information that is available to the risk assessor and specifically on the probabilistic exposure factor distributions that are developed and used in the exposure and risk models. Deriving probabilistic distributions for model inputs can be time consuming and subjective. The absence of a standard approach for developing these distributions can result in PRAs that are inconsistent and difficult to review by regulatory agencies. We present an approach that reduces subjectivity in the distribution development process without limiting the flexibility needed to prepare relevant PRAs. The approach requires two steps. First, we analyze data pooled at a population scale to (1) identify the most robust demographic variables within the population for a given exposure factor, (2) partition the population data into subsets based on these variables, and (3) construct archetypal distributions for each subpopulation. Second, we sample from these archetypal distributions according to site- or scenario-specific conditions to simulate exposure factor values and use these values to construct the scenario-specific input distribution. It is envisaged that the archetypal distributions from step 1 will be generally applicable so risk assessors will not have to repeatedly collect and analyze raw data for each new assessment. We demonstrate the approach for two commonly used exposure factors--body weight (BW) and exposure duration (ED)--using data for the U.S. population. For these factors we provide a first set of subpopulation based archetypal distributions along with methodology for using these distributions to construct relevant scenario-specific probabilistic exposure factor distributions.

  12. Infant metabolic screening: a total quality management approach.

    Science.gov (United States)

    Forsberg, S A

    1997-01-01

    The principles of total quality management (TQM) were used to improve the infant metabolic screening program in a large urban hospital. Three quality indicators needed improvement; unsatisfactory specimen quality, delayed delivery to the state laboratory for testing, and specimen slips missing the date of collection. A multidisciplinary team identified the root causes of the poor quality and implemented remedies. Dramatic improvement in three infant screening indicators occurred within a 4-month period. Evaluation of the three indicators continued for the following 3-year period. Quality improvement programs that involve a multidisciplinary approach benefit the patient and staff and may reduce costs.

  13. Approaches to the quality management in tourism services

    Directory of Open Access Journals (Sweden)

    Ida Vajčnerová

    2010-01-01

    Full Text Available The paper focuses on the systems of quality used in tourism services. It introduces approaches based on observing facility standards that are used in the Czech Republic in the area of accommodation and boarding services (Hotelstars, HACAP, then ISO standards of 9000 group and the systems of complex quality management. Within the frame of complex quality management it deals with the model of exceptionality EFQM (European Foundation for Quality Management and the European integrated system of quality IQM (Integrated Quality Management in more detail. The necessity to support the quality of tourism services is pointed out in the paper, as well as to create a national system of quality or possibly using already existing European systems of international character.

  14. SIX SIGMA - A NEW APPROACH OF QUALITY

    Directory of Open Access Journals (Sweden)

    Maria Nicolai, Sofia Totolici

    2005-01-01

    Full Text Available The term six sigma was elaborated by Motorola Corp, in the early ‘80s, after a visit in Japan. The method’s application with this name has reduced the fabrication deficiencies with 99,7%, thus, in 1998, Motorola Corp. was one of the first companies to receive The Quality National Award in USA,“Malcolm Baldrige”. Then the method was used by other companies as well, which have declared that using the six sigma method, the 3,4 deficiencies per million of opportunities level may beachieved, attaining not perfection, but almost perfection.

  15. A structured ecosystem-scale approach to marine water quality ...

    African Journals Online (AJOL)

    A structured ecosystem-scale approach to marine water quality management ... environmentally responsible and sustainable development practices, either ... which to design and implement environmental management programmes. ... It also aims to support and stimulate local stakeholder empowerment and involvement.

  16. Structured ecosystem-scale approach to marine water quality management

    CSIR Research Space (South Africa)

    Taljaard, Susan

    2006-10-01

    Full Text Available and implement environmental management programmes. A structured ecosystem-scale approach for the design and implementation of marine water quality management programmes developed by the CSIR (South Africa) in response to recent advances in policies...

  17. An Approach to Measuring Software Quality Perception

    Science.gov (United States)

    Hofman, Radoslaw

    Perception measuring and perception management is an emerging approach in the area of product management. Cognitive, psychological, behavioral and neurological theories, tools and methods are being employed for a better understanding of the mechanisms of a consumer's attitude and decision processes. Software is also being defined as a product, however this kind of product is significantly different from all other products. Software products are intangible and it is difficult to trace their characteristics which are strongly dependant on a dynamic context of use.

  18. A cooperative approach to ensure software product quality

    Directory of Open Access Journals (Sweden)

    M Sangeetha

    2011-07-01

    Full Text Available Quality is the process of ensuring that software developed satisfies customer requirements. Among the many software quality attributes like functionality, usability, capability, maintainability, etc., reliability is a major factor to assure quality of the software. Reliability ensures that software is failure free. In this work, we propose to ensure quality through a behavioral model that evaluates business requirements and gives priority for quality attributes. The model consists of behavioural and human perspectives in assessment. It is used for assessment of software developed.

  19. Quality Evaluation in Flexible Manufacturing Systems: A Markovian Approach

    Directory of Open Access Journals (Sweden)

    Jingshan Li

    2007-01-01

    to illustrate the applicability of the method. The results of this study suggest a possible approach to investigate the impact of flexibility on product quality and, finally, with extensions and enrichment of the model, may lead to provide production engineers and managers a better understanding of the quality implications and to summarize some general guidelines of operation management in flexible manufacturing systems.

  20. The deformed uncertainty relation and the corresponding beam quality factor

    CERN Document Server

    Li, K; Wang, S M; Li, Kang; Zhao, Dao Mu; Wang, Shao Min

    1996-01-01

    By using the theory of deformed quantum mechanics, we study the deformed light beam theoretically. The deformed beam quality factor M_q^2 is given explicitly under the case of deformed light in coherent state. When the deformation parameter q being a root of unity, the beam quality factor M_q^2 \\leq 1.

  1. Radiation quality factor of spherical antennas with material cores

    DEFF Research Database (Denmark)

    Hansen, Troels Vejle; Kim, Oleksiy S.; Breinbjerg, Olav

    2011-01-01

    This paper gives a description of the radiation quality factor and resonances of spherical antennas with material cores. Conditions for cavity and radiating resonances are given, and a theoretical description of the radiation quality factor, as well as simple expressions describing the relative...

  2. Quality- a Factor of Management in Road Transport of Goods

    Directory of Open Access Journals (Sweden)

    Livij Jakomin

    2012-10-01

    Full Text Available Providing services on a quality level is an important factorof management in the trade rivalry for the control over the market.The factors affecting quality comprise technical factors andoperational and organisational ones. The technical factors includethe choice, the due care and maintenance of the vehicle.The operational and organisational factors are the quality offer,performing the transport service, the response in case of action,and the information efficiency.The necessity to control the total quality management is theresponsibility of the management. All staff members must participatein the improvement of quality management in their particularworking environment. Improved quality managementprovides for a higher safety of business operation and jobs, resultingin enhanced social security, which is gaining importancein mutual relations.

  3. Supply Chain Quality Management in Agribusiness: An Approach of Quality Management Systems in Food Supply Chains

    OpenAIRE

    Mendes dos Reis, João,; Machado, Sivanilza,; Costa Neto, Pedro,; Monteiro, Rogério; Sacomano, José,

    2014-01-01

    Part 2: Case Studies; International audience; It is widely accepted that Quality Management Systems approach is indicated to ensure quality of products and services. Furthermore, Total Quality Management, Six Sigma, ISO Standards and Hoshin Kanri have established as important management systems for quality guarantee in many production processes. Unfortunately, these systems are not familiar to agribusiness companies. The aim of this study is to analyze the benefits of application of tradition...

  4. An approach to ensuring quality in environmental software

    Energy Technology Data Exchange (ETDEWEB)

    Gelston, G.M.; Lundgren, R.E.; McDonald, J.P.; Hoopes, B.L.

    1998-05-01

    Environmental software is often used to determine impacts to the public, workers, and the environment from environmental contamination. It is vital, therefore, that the modeling results, and the software that provides them, be scientifically defensible and capable of withstanding the most rigorous of technical reviews. The control and assurance of quality is a critical factor for the project team that develops environmental software at the Pacific Northwest National Laboratory. This document describes the philosophy, process, and activities that ensure a quality product throughout the life cycle of requirements analysis, design, programming, modification, testing, and implementation of environmental software. Environmental software developed by the project team is designed using an object-oriented approach. This software offers increased benefits, such as ease of maintenance and retention of the development and testing legacy of individual components, over traditional hard wired software. These benefits allow the design and testing of the models and future additions to be faster and less costly. This software is developed using a modular framework concept that allows a variety of models to work within a single construct. This software has two parts: an overall system framework and a set of modules. Each module has up to three components: a user interface, a scientific model, and pre/post-processors. Each of these pieces has a different set of quality criteria associated with it. However, whatever form this software might take for a particular client, standard processes apply to protect the information from inappropriate use. The information contained within this document can be applied to most environmental software to analyze risk in multiple environmental media.

  5. MULTILAYER MICROSTRIP ANTENNA QUALITY FACTOR OPTIMIZATION FOR BANDWIDTH ENHANCEMENT

    Directory of Open Access Journals (Sweden)

    M.C. SRIVASTAVA

    2012-12-01

    Full Text Available The impedance bandwidth, one of the important characteristics of microstrip patch antennas, can be significantly improved by using a multilayer dielectric configuration. In this paper the focus is on bandwidth enhancement technique of a multilayer patch antenna for X-band applications. In order to enhance the bandwidth, antenna losses are contained by controlling those quality factors which can have a significant impact on the bandwidth for a given permittivity and thickness of the substrate. This has been achieved by conformal transformation of the multidielectric microstrip antenna. For the ease of analysis Wheelers transformation is used to map the complex permittivity of a multilayer substrate to a single layer. Method of Moments and Finite Difference Time Domain approaches are used for the computation of results.

  6. Quality of life in schizophrenia: A grounded theory approach

    Directory of Open Access Journals (Sweden)

    Jackson Mike

    2003-08-01

    Full Text Available Abstract Background Research into health related quality of life (HRQoL in schizophrenia has predominantly been conducted using lengthy interviewer administered questionnaires, many of which have not been validated for use with schizophrenic samples. The present study seeks to address the dearth of qualitative research by conducting a small-scale qualitative exploration of the impact of schizophrenia on HRQoL. Method The study was conducted using the qualitative approach of grounded theory. Six individuals with a diagnosis of schizophrenia participated (3 men, 3 women. Mean age of participants was 33.3 years (range 20–55, mean length of illness was 12 years (range 2–38 years and average length of interviews was 47 minutes (range 20–70. Results Ten HRQoL domains were identified as being important: (1 barriers placed on relationships; (2 reduced control of behaviours and actions; (3 loss of opportunity to fulfil occupational roles; (4 financial constraints on activities and plans; (5 subjective experience of psychotic symptoms; (6 side effects and attitudes to medication; (7 psychological responses to living with schizophrenia; (8 labelling and attitudes from others; (9 concerns for the future and (10 positive outcomes from experiences. Conclusions Domains identified by participants encompassed a wide range of factors that may be expected to contribute generally to engaging in a positive quality of life. Participants identified that it was the loss of these things as a direct consequence of having schizophrenia that influenced their HRQoL. It would appear that in the main, factors that are secondary to the experience of schizophrenia are of most importance to participants. Suggestions are also made in the discussion for future research.

  7. Approaches in breeding for high quality protein maize

    Directory of Open Access Journals (Sweden)

    Denić Miloje

    2008-01-01

    Full Text Available Maize is the principal crop and major staple food in the most African and South American countries. The main problem in human nutrition in developing countries, and in livestock feed in developed countries, is insufficient production and poor quality of cereal proteins. In the case of maize, due to the very low content of essential amino acids lysine and tryptophan in grain endosperm, biological value is very low, which is main limiting factor of common maize in human nutrition and feeding of monogastric animals. Quality protein maize (QPM can help in solving of this problem. Maize production also faces serious constraints caused by agro-ecological conditions and poor socio-economic situation. To alleviate the effect of the constraints, selected genotypes with more desirable traits and appropriate field-plot techniques to create multiple-stress conditions, were used. It was found that, in downy mildew nursery distance up to 35 m from spreader plot is providing sufficient down load of spores for plant infection, provided that the testing breeding materials are planted towards to down-stream direction of the dominant wind. Using these breeding approaches large number of early, white and flint synthetics, composites and inbred lines were created with resistance or tolerance to downy mildew (DMR, maize streak virus (SR and drought (DT. Created genotypes exhibited very good kernel modification and yield potential under low and normal inputs. In the case of synthetics and composites, besides tolerance to multiple stress factors, they were competing in yield with local QPM and normal maize checks. In the case of created inbred lines high combining ability was exhibited both in non-conventional and conventional maize hybrids. Trial data revealed that in the most cases the best entries were over-yielding the best checks.

  8. THE FACTORS FORMING QUALITY OF GRANULATED SUGAR

    Directory of Open Access Journals (Sweden)

    N. G. Kulneva

    2015-01-01

    Full Text Available Sugar, with good taste and high caloric, is one of the most popular human food. Consumers sugar must be sure that the sugar under normal conditions of use is of high quality and is not harmful to the health of the product. One reason for the decline in the quality of sugar is bacterial contamination. This is because the sugar industry products are good targets for the development of different groups of microorganisms, e.g., Bacillus subtilis, Clostridium perfringes, Leuconostoc dextranicum, Torula alba, Pseudomonas fluorescens, Sarcina lutea and others. These organisms are affected with beets, and then with sugar beet chips and diffusion juice fall into the processing line of sugar production. Their number in the diffusion juice varies and depends on many facto rs such as the quality of raw materials, the quality of cleaning beet root colonization of transporter-washing and the supply of water to the diffusion process, the temperature of the diffusion and others. In the diffusion unit has the most favorable conditions for the development of micro-organisms. Some of them, especially resistant bacteria and thermophilic bacteria or their spores, forming a capsule which protects against external influences occur in the final product sugar. When injected into the fresh crop of product (juice, syrup, they begin to multiply rapidly, causing difficulties in the process. The higher seeding beet microorganisms, the more they decompose and emit sucrose metabolism byproducts. To reduce the negative impact of microbiological and reduce losses from decomposition of sucrose conducted research on the possibility of using chlorine-containing substances in the sugar industry. It was established experimentally that the investigated chlorinated drug has bacteriostatic action and can be recommended for use in sugar beet production.

  9. Quality management, a directive approach to patient safety.

    Science.gov (United States)

    Ayuso-Murillo, Diego; de Andrés-Gimeno, Begoña; Noriega-Matanza, Concha; López-Suárez, Rafael Jesús; Herrera-Peco, Ivan

    Nowadays the implementation of effective quality management systems and external evaluation in healthcare is a necessity to ensure not only transparency in activities related to health but also access to health and patient safety. The key to correctly implementing a quality management system is support from the managers of health facilities, since it is managers who design and communicate to health professionals the strategies of action involved in quality management systems. This article focuses on nursing managers' approach to quality management through the implementation of cycles of continuous improvement, participation of improvement groups, monitoring systems and external evaluation quality models (EFQM, ISO). The implementation of a quality management system will enable preventable adverse effects to be minimized or eliminated, and promote patient safety and safe practice by health professionals. Copyright © 2017 Elsevier España, S.L.U. All rights reserved.

  10. Therapeutic approaches for tumor necrosis factor inhibition

    Directory of Open Access Journals (Sweden)

    Maria Letícia de Castro Barbosa

    2011-09-01

    Full Text Available Tumor necrosis factor (TNF consists of an inflammatory cytokine essential for homeostasis and organism defense. Despite its physiological relevance, both increased biosynthesis and release of TNF lead to the exacerbation of inflammatory and oxidative responses, which are related to the pathogenesis of a host of diseases of an inflammatory, autoimmune and/or infectious nature. In this context, effective therapeutic approaches for the modulation of TNF have been the focus of research efforts. Approximately one million individuals worldwide have been treated with biotechnological inhibitors of this cytokine, the so-called anti-TNF biopharmaceuticals. However, given the high risk of infection and the limitations related to cost and administration routes, new therapeutic approaches aimed at biological targets that directly or indirectly modulate the production and/or activation of TNF appear promising alternatives for the discovery of new anti-inflammatory and immunomodulatory orally active drugs and are therefore discussed in this paper.O fator de necrose tumoral (do inglês, tumor necrosis factor - TNF consiste em uma citocina inflamatória essencial para a homeostase e defesa do organismo. A despeito de sua relevância fisiológica, o aumento da biossíntese e liberação do TNF conduzem à exacerbação das respostas inflamatória e oxidativa, as quais estão relacionadas à patogênese de várias doenças de natureza inflamatória, auto-imune e/ou infecciosa. A busca por abordagens terapêuticas eficientes na modulação do TNF tem sido alvo de diversos esforços de pesquisa. Aproximadamente um milhão de pessoas ao redor do mundo já foi tratado com inibidores biotecnológicos desta citocina, os chamados biofármacos anti-TNF. Entretanto, em face ao elevado risco de infecções e as limitações relacionadas ao custo e a via de administração, novas abordagens terapêuticas com foco em alvos que modulem, de forma direta ou indireta, a produ

  11. An Unified Approach for Process Quality Analysis and Control

    Directory of Open Access Journals (Sweden)

    Prof.Chandrakanth Biradar,Aruna Kawdi

    2012-09-01

    Full Text Available Abstract— The process in a company finally results in product of the company, which represents the company standard. Hence, during the process execution time quality of the process needs to be taken care before and after the work done. In this paper, an unified approach to quality analysis and control of a process development is presented. This approach gives an overview of what the task the company assigned to the employers. The process is defined as the set of action items to achieve the work completion. Quality means grade of excellence. Quality analysis of a process is an improvement of the process and making sure that all the standard procedures are followed. An unified approach designed in this paper is a combination of software cost estimation and a financial market forecasting with the support of historical data, statistical data mining technique and artificial neural networks, which helps the developers as well as investors in strategic planning and investment decision making. Therefore, the paper describes a recommended process to develop software (SW cost estimates for software managers, perform financial market forecasting to control quality of process development. As a result, the improvement and analysis of the process quality can be performed from basic level to the corporate level. By this work, we conclude that the process quality control can be made easier and efficient compared to the old graphical analytics technique.

  12. Subjective sleep quality in perimenopausal women and its related factors

    Institute of Scientific and Technical Information of China (English)

    Jianping Zhang; Fen Lia; Yongjie Lin; Qiu Sheng; Xuewen Yu; Xinwen Zhang

    2007-01-01

    Objective: To evaluate the sleep quality and its related factors among perimenopausal women. Methods: A self-designed questionnaire was administered to 506 perimenopausal women. The questionnaire included the influencing factors on the sleep quality, the Pittsburgh Sleep Quality Index (PSQI), the Zung Self-Rating Depression Scales (SDS), the Zung Self-Rating Anxiety (SAS) and the Modified Kupperman Index (KI). Data were analyzed by SPSS11.5. Results: The mean PSQI was 5.97±4.30.Twenty-four percent of perimenopausal women reported poor sleep. Age and perimenopausal symptoms were significantly correlated with sleep quality. The sleep quality of the 45~49 age group was the poorest and the 40~44 age group was the best. The women who had higher Kupperman index were more likely to be poor sleepers. There was no significant correlation between occupation and sleep quality. Night sweat, depression, anxiety, hot flash, stressful life event, and regular exercise were significantly and independently related with sleep quality. Among them, regular exercise was a protective factor of sleep quality. Conclusion:High incidence of poor sleep quality exists among perimenopausal women. Some effective interventions should be taken to improve the sleep quality of perimenopausal women.

  13. A scientific approach to quality in R and D

    Energy Technology Data Exchange (ETDEWEB)

    Kidd, G.J. Jr.

    1989-01-01

    As quality concepts are beginning to be applied to areas other than traditional manufacturing environments, we see a whole spectrum of results. So far it has been hard to predict when a quality program will succeed or fail or to understand why. This paper explains why the difficulty exists; it also presents an approach that enhances the probability that a program will be acceptable to the scientific community, an approach that is based on systems analysis and uses nomenclature and techniques already familiar to technically trained people. This approach extends some of the existing quality principles to allow more focus on processes than on products. Recognizing that much of the output of scientific effort is subjective, it proposed some alternatives for measuring and evaluating those types of results. 13 refs., 4 figs.

  14. The consistency approach for the quality control of vaccines.

    Science.gov (United States)

    Hendriksen, Coenraad; Arciniega, Juan L; Bruckner, Lukas; Chevalier, Michel; Coppens, Emmanuelle; Descamps, Johan; Duchêne, Michel; Dusek, David Michael; Halder, Marlies; Kreeftenberg, Hans; Maes, Alexandrine; Redhead, Keith; Ravetkar, Satish D; Spieser, Jean-Marc; Swam, Hanny

    2008-01-01

    Current lot release testing of conventional vaccines emphasizes quality control of the final product and is characterized by its extensive use of laboratory animals. This report, which is based on the outcome of an ECVAM (European Centre for Validation of Alternative Methods, Institute for Health and Consumer Protection, European Commission Joint Research Centre, Ispra, Italy) workshop, discusses the concept of consistency testing as an alternative approach for lot release testing. The consistency approach for the routine release of vaccines is based upon the principle that the quality of vaccines is a consequence of a quality system and of consistent production of lots with similar characteristics to those lots that have been shown to be safe and effective in humans or the target species. The report indicates why and under which circumstances this approach can be applied, the role of the different stakeholders, and the need for international harmonization. It also gives recommendations for its implementation.

  15. Quality by design approach for formulation development: a case study of dispersible tablets.

    Science.gov (United States)

    Charoo, Naseem A; Shamsher, Areeg A A; Zidan, Ahmed S; Rahman, Ziyaur

    2012-02-28

    The focus of the current investigations was to apply quality by design (QbD) approach to the development of dispersible tablets. Critical material and process parameters are linked to the critical quality attributes of the product. Variability is reduced by product and process understanding which translates into quality improvement, risk reduction and productivity enhancement. The risk management approach further leads to better understanding of the risks, ways to mitigate them and control strategy is proposed commensurate with the level of the risk. Design space in combination with pharmaceutical quality management system provide for flexible regulatory approaches with opportunity for continuous improvement that benefit patient and manufacturer alike. The development of dispersible tablet was proposed in the current study through a QbD paradigm for a better patient compliance and product quality. The quality target product profile of a model biopharmaceutical class II drug was identified. Initial risk analysis led to the identification of the critical quality attributes. Physicochemical characterization and compatibility studies of the drug with commonly used excipients were performed. Experiments were designed with focus on critical material and process attributes. Design space was identified and risk factors for all the possible failure modes were below critical levels after the implementation of control strategy. Compliance to the design space provides an opportunity to release batches in a real time. In conclusion, QbD tools together with risk and quality management tools provided an effective and efficient paradigm to build the quality into dispersible tablet.

  16. Dietary quality, lifestile factors and healthy ageing in Europe

    NARCIS (Netherlands)

    Haveman-Nies, A.

    2001-01-01

    Keywords: dietary quality, dietary patterns, lifestyle factors, smoking, physical activity, elderly, mortality, Mediterranean Diet Score, Healthy Diet Indicator, healthy ageing, self-rated health, functional status


    The contribution o

  17. PARETO ANALYSIS OF TOTAL QUALITY MANAGEMENT FACTORS CRITICAL TO SUCCESS FOR SERVICE INDUSTRIES

    OpenAIRE

    Faisal Talib; Zillur Rahman; M. N. Qureshi

    2010-01-01

    Total quality management (TQM) is an integrated management approach that aim to continuously improve the performance of products, processes, and services to achieve and surpass customer's expectations. To accomplish this objective, some key factors that contribute to the success of TQM efforts are to be identified. These key factors are often termed as critical success factors (CSFs). The purpose of the present study is to identify and propose a list of "vital few" TQM CSFs for the benefit of...

  18. A Sensitivity Analysis Approach to Identify Key Environmental Performance Factors

    Directory of Open Access Journals (Sweden)

    Xi Yu

    2014-01-01

    Full Text Available Life cycle assessment (LCA is widely used in design phase to reduce the product’s environmental impacts through the whole product life cycle (PLC during the last two decades. The traditional LCA is restricted to assessing the environmental impacts of a product and the results cannot reflect the effects of changes within the life cycle. In order to improve the quality of ecodesign, it is a growing need to develop an approach which can reflect the changes between the design parameters and product’s environmental impacts. A sensitivity analysis approach based on LCA and ecodesign is proposed in this paper. The key environmental performance factors which have significant influence on the products’ environmental impacts can be identified by analyzing the relationship between environmental impacts and the design parameters. Users without much environmental knowledge can use this approach to determine which design parameter should be first considered when (redesigning a product. A printed circuit board (PCB case study is conducted; eight design parameters are chosen to be analyzed by our approach. The result shows that the carbon dioxide emission during the PCB manufacture is highly sensitive to the area of PCB panel.

  19. A convolutional neural network approach for objective video quality assessment.

    Science.gov (United States)

    Le Callet, Patrick; Viard-Gaudin, Christian; Barba, Dominique

    2006-09-01

    This paper describes an application of neural networks in the field of objective measurement method designed to automatically assess the perceived quality of digital videos. This challenging issue aims to emulate human judgment and to replace very complex and time consuming subjective quality assessment. Several metrics have been proposed in literature to tackle this issue. They are based on a general framework that combines different stages, each of them addressing complex problems. The ambition of this paper is not to present a global perfect quality metric but rather to focus on an original way to use neural networks in such a framework in the context of reduced reference (RR) quality metric. Especially, we point out the interest of such a tool for combining features and pooling them in order to compute quality scores. The proposed approach solves some problems inherent to objective metrics that should predict subjective quality score obtained using the single stimulus continuous quality evaluation (SSCQE) method. This latter has been adopted by video quality expert group (VQEG) in its recently finalized reduced referenced and no reference (RRNR-TV) test plan. The originality of such approach compared to previous attempts to use neural networks for quality assessment, relies on the use of a convolutional neural network (CNN) that allows a continuous time scoring of the video. Objective features are extracted on a frame-by-frame basis on both the reference and the distorted sequences; they are derived from a perceptual-based representation and integrated along the temporal axis using a time-delay neural network (TDNN). Experiments conducted on different MPEG-2 videos, with bit rates ranging 2-6 Mb/s, show the effectiveness of the proposed approach to get a plausible model of temporal pooling from the human vision system (HVS) point of view. More specifically, a linear correlation criteria, between objective and subjective scoring, up to 0.92 has been obtained on

  20. Assessment of CT image quality using a Bayesian approach

    Science.gov (United States)

    Reginatto, M.; Anton, M.; Elster, C.

    2017-08-01

    One of the most promising approaches for evaluating CT image quality is task-specific quality assessment. This involves a simplified version of a clinical task, e.g. deciding whether an image belongs to the class of images that contain the signature of a lesion or not. Task-specific quality assessment can be done by model observers, which are mathematical procedures that carry out the classification task. The most widely used figure of merit for CT image quality is the area under the ROC curve (AUC), a quantity which characterizes the performance of a given model observer. In order to estimate AUC from a finite sample of images, different approaches from classical statistics have been suggested. The goal of this paper is to introduce task-specific quality assessment of CT images to metrology and to propose a novel Bayesian estimation of AUC for the channelized Hotelling observer (CHO) applied to the task of detecting a lesion at a known image location. It is assumed that signal-present and signal-absent images follow multivariate normal distributions with the same covariance matrix. The Bayesian approach results in a posterior distribution for the AUC of the CHO which provides in addition a complete characterization of the uncertainty of this figure of merit. The approach is illustrated by its application to both simulated and experimental data.

  1. Quality of life - the factor of Russia success at present and in the future

    Directory of Open Access Journals (Sweden)

    Berkalov S. V.

    2016-01-01

    Full Text Available The quality of life and human development - these concepts are substantial characteristics of contemporary approaches to the challenges of economic growth and development of society. The quality of life in contemporary quality concepts means the integrated characteristics of social-economic, political, cultural-ideologic, ecologic factors and living conditions and social status of a person. State policy in the field of regulating population’s quality of life and living standards is the basis of creating totally new work force, essential needs in material wealth, life quality and working conditions indicators. We consider the definition "quality of life" within the concept of human development to define the system of the factors influencing it. We review the modern approaches to the analysis of the quality of life. Features and aspects of quality of life are considered, its role in social and economic development of the country is analysed. The main criteria define specifics of human development and social wellbeing of the population. To evaluate the quality of life of the population we use the statistical analysis of the United Nations (UN, Human Development Index (HDI.We conclude that the level of life is an integrated social and economic category that presents the level of development of physical, immaterial and social needs which influence the quality of life and population wellbeing Index.

  2. Ecological quality of production: accounting approach on sustainable development

    Directory of Open Access Journals (Sweden)

    N.P. Syroid

    2016-12-01

    Full Text Available The specific weight of resource and power consuming technologies that is typical for Ukrainian economy, the absence of effective legal, administrative and economic mechanisms of management of nature and the low level of ecological society consciousness have led to the significant deterioration of environment state in Ukraine, excessive pollution of waters, air, and soil, accumulation of a large number of waste products. Besides, the produce as a result of such enterprises’ production affects consumers’ health badly. This causes the need to develop theory and methodology of production ecological quality accounting. The problem of quality is the most important factor of increasing of life level, economic, social and ecological security in market economy. This, the current research aims to formulate the essence of concept “ecological quality of production” The research determines that ecological quality is characterized by the following main 6 aspects: social, technical, legal, economic, aesthetic and ecological. If one of these six aspects does not work, we cannot speak about ecological quality of a certain commodity. Many various factors influence upon the level of ecological quality of products and services. According to their contents and directions, they can be united into the following main 6 groups: technical, organizational, economic and social, ecological and aesthetic and legal. The article determines the directions of production ecological quality increasing.

  3. Taking Teacher Quality Seriously: A Collaborative Approach to Teacher Evaluation

    Science.gov (United States)

    Karp, Stan

    2012-01-01

    If narrow, test-based evaluation of teachers is unfair, unreliable, and has negative effects on kids, classrooms, and curricula, what's a better approach? By demonizing teachers and unions, and sharply polarizing the education debate, the corporate reform movement has actually undermined serious efforts to improve teacher quality and evaluation.…

  4. Taking Teacher Quality Seriously: A Collaborative Approach to Teacher Evaluation

    Science.gov (United States)

    Karp, Stan

    2012-01-01

    If narrow, test-based evaluation of teachers is unfair, unreliable, and has negative effects on kids, classrooms, and curricula, what's a better approach? By demonizing teachers and unions, and sharply polarizing the education debate, the corporate reform movement has actually undermined serious efforts to improve teacher quality and evaluation.…

  5. Revisiting Cyberbullying in Schools Using the Quality Circle Approach

    Science.gov (United States)

    Paul, Simone; Smith, Peter K.; Blumberg, Herbert H.

    2012-01-01

    An earlier study reported the use of Quality Circles (QC) in a UK school in the context of understanding and reducing bullying and cyberbullying. Here, we report further work in the same school setting. The QC approach allows explorative analysis of problems in school settings, whereby students embark on a problem-solving exercise over a period of…

  6. Global approaches and opportunities for quality assesment of higher education

    OpenAIRE

    YARNYKH VERONICA; MAKAROVA NATALIA

    2016-01-01

    The global labor competition imposes on graduates fundamentally new requirements for the competence profile. Evaluation of the quality of higher education results is one of the possibilities to strengthen the competitive position of the university and its graduates in a competitive global environment. The use of international approaches in this area enables additional competitive advantage in global competition.

  7. Assessing the Learning Path Specification: a Pragmatic Quality Approach

    NARCIS (Netherlands)

    Janssen, José; Berlanga, Adriana; Heyenrath, Stef; Martens, Harrie; Vogten, Hubert; Finders, Anton; Herder, Eelco; Hermans, Henry; Melero, Javier; Schaeps, Leon; Koper, Rob

    2010-01-01

    Janssen, J., Berlanga, A. J., Heyenrath, S., Martens, H., Vogten, H., Finders, A., Herder, E., Hermans, H., Melero Gallardo, J., Schaeps, L., & Koper, R. (2010). Assessing the Learning Path Specification: a Pragmatic Quality Approach. Journal of Universal Computer Science, 16(21), 3191-3209.

  8. Revisiting Cyberbullying in Schools Using the Quality Circle Approach

    Science.gov (United States)

    Paul, Simone; Smith, Peter K.; Blumberg, Herbert H.

    2012-01-01

    An earlier study reported the use of Quality Circles (QC) in a UK school in the context of understanding and reducing bullying and cyberbullying. Here, we report further work in the same school setting. The QC approach allows explorative analysis of problems in school settings, whereby students embark on a problem-solving exercise over a period of…

  9. New approach to equipment quality evaluation method with distinct functions

    Directory of Open Access Journals (Sweden)

    Milisavljević Vladimir M.

    2016-01-01

    Full Text Available The paper presents new approach for improving method for quality evaluation and selection of equipment (devices and machinery by applying distinct functions. Quality evaluation and selection of devices and machinery is a multi-criteria problem which involves the consideration of numerous parameters of various origins. Original selection method with distinct functions is based on technical parameters with arbitrary evaluation of each parameter importance (weighting. Improvement of this method, presented in this paper, addresses the issue of weighting of parameters by using Delphi Method. Finally, two case studies are provided, which included quality evaluation of standard boilers for heating and evaluation of load-haul-dump (LHD machines, to demonstrate applicability of this approach. Analytical Hierarchical Process (AHP is used as a control method.

  10. Intelligent Systems Approaches to Product Sound Quality Analysis

    Science.gov (United States)

    Pietila, Glenn M.

    As a product market becomes more competitive, consumers become more discriminating in the way in which they differentiate between engineered products. The consumer often makes a purchasing decision based on the sound emitted from the product during operation by using the sound to judge quality or annoyance. Therefore, in recent years, many sound quality analysis tools have been developed to evaluate the consumer preference as it relates to a product sound and to quantify this preference based on objective measurements. This understanding can be used to direct a product design process in order to help differentiate the product from competitive products or to establish an impression on consumers regarding a product's quality or robustness. The sound quality process is typically a statistical tool that is used to model subjective preference, or merit score, based on objective measurements, or metrics. In this way, new product developments can be evaluated in an objective manner without the laborious process of gathering a sample population of consumers for subjective studies each time. The most common model used today is the Multiple Linear Regression (MLR), although recently non-linear Artificial Neural Network (ANN) approaches are gaining popularity. This dissertation will review publicly available published literature and present additional intelligent systems approaches that can be used to improve on the current sound quality process. The focus of this work is to address shortcomings in the current paired comparison approach to sound quality analysis. This research will propose a framework for an adaptive jury analysis approach as an alternative to the current Bradley-Terry model. The adaptive jury framework uses statistical hypothesis testing to focus on sound pairings that are most interesting and is expected to address some of the restrictions required by the Bradley-Terry model. It will also provide a more amicable framework for an intelligent systems approach

  11. Hypothesis Generation in Quality Improvement Projects: Approaches for Exploratory Studies

    NARCIS (Netherlands)

    de Mast, J.; Bergman, M.

    2006-01-01

    In quality improvement projects - such as Six Sigma projects - an exploratory phase can be discerned, during which possible causes, influence factors or variation sources are identified. In a subsequent confirmatory phase the effects of these possible causes are experimentally verified. Whereas the

  12. Block-based approach to modelling of granulated fertilizers' quality

    DEFF Research Database (Denmark)

    Kohonen, J.; Reinikainen, S. P.; Høskuldsson, Agnar

    2009-01-01

    Fertilizer manufacturing is a customer-driven industry, where the quality of a product is a key factor in order to survive the competition. However, measuring the most important feature with granulated fertilizers, flowability, is tedious, time-consuming and thus expensive. Flowability can...

  13. An Approach to Early Prediction of Software Quality

    Institute of Scientific and Technical Information of China (English)

    YAO Lan; YANG Bo

    2007-01-01

    Due to the rapid development of computers and their applications, early software quality prediction in software industry becomes more and more crucial. Software quality prediction model is very helpful for decision-makings such as the allocation of resource in module verification and validation. Nevertheless, due to the complicated situations of software development process in the early stage, the applicability and accuracy of these models are still under research. In this paper, a software quality prediction model based on a fuzzy neural network is presented, which takes into account both the internal factors and external factors of software. With hybrid-learning algorithm, the proposed model can deal with multiple forms of data as well as incomplete information, which helps identify design errors early and avoid expensive rework.

  14. DETERMINANT FACTORS OF FINANCIAL REPORTING QUALITY AND ECONOMIC CONSEQUENCES

    Directory of Open Access Journals (Sweden)

    Zaenal Fanani

    2017-03-01

    Full Text Available The aim of this research was to prove empirically the determining factors that influence the quality of financialreporting and the economic consequences, and there were influence differences of quality attributes of financialreporting to the economic consequences. The research samples were taken by purposive sampling so it obtained141 listed manufacturing businesses from 2001 to 2006. The research used four data analysis technique:auxiliary regression R2, confirmatory factor analysis, simple regression, and multiple regressions. The resultsshowed seven attributes, there were five attributes that gave contribution for financial reporting quality namelyaccrual quality, predictability, smoothness, relevance value, and conservatism while the persistence and timelinessgave small contribution. The five attributes were also different each other. From the thirteen determiningfactors, it showed nine factors that produced significant influences namely operation cycle, sales volatility,firm size, firm age, loss proportion, leverage, environmental risk, institutional ownership, market concentration,and auditor quality, while the other three, they were liquidity, managerial ownership, and investmentgrowth that were not significant. Testing results of economic consequences of quality of financial reportingshowed that the quality of factorial financial reporting influenced negatively and significantly toward informationasymmetry.

  15. Broken symmetry dielectric resonators for high quality-factor Fano metasurfaces

    CERN Document Server

    Campione, Salvatore; Basilio, Lorena I; Warne, Larry K; Langston, William L; Luk, Ting S; Wendt, Joel R; Reno, John L; Keeler, Gordon A; Brener, Igal; Sinclair, Michael B

    2016-01-01

    We present a new approach to dielectric metasurface design that relies on a single resonator per unit cell and produces robust, high quality-factor Fano resonances. Our approach utilizes symmetry breaking of highly symmetric resonator geoemetries, such as cubes, to induce couplings between the otherwise orthogonal resonator modes. In particular, we design perturbations that couple "bright" dipole modes to "dark" dipole modes whose radiative decay is suppressed by local field effects in the array. Our approach is widely scalable from the near-infrared to radio frequencies. We first unravel the Fano resonance behavior through numerical simulations of a germanium resonator-based metasurface that achieved a quality-factor of ~1300 at ~10.8 um. Then, we present two experimental demonstrations operating in the near-infrared (~1 um): a silicon-based implementation that achieved a quality-factor of ~350; and a gallium arsenide-based structure that achieves a quality-factor of ~600 - the highest near-infrared quality-...

  16. Evaluating Journal Quality: Is the H-Index a Better Measure than Impact Factors?

    Science.gov (United States)

    Hodge, David R.; Lacasse, Jeffrey R.

    2011-01-01

    Objectives: This study evaluates the utility of a new measure--the h-index--that may provide a more valid approach to evaluating journal quality in the social work profession. Method: H-index values are compared with Thomson ISI 5-year impact factors and expert opinion. Results: As hypothesized, the h-index correlates highly with ISI 5-year impact…

  17. A Strategic Approach To Managing Customer Service Quality

    Directory of Open Access Journals (Sweden)

    Nelson Barber

    2011-11-01

    Full Text Available Service quality is an essential strategy for success and survival in today's competitive environment. Earlier discussions emphasized what service quality meant to customers and how to develop strategies to meet customer expectations. More recently, the focus has shifted to understanding the impact of service quality on profit and other financial outcomes of the organization. Lowering customer defection rates can be profitable to companies, at the same time lowering employee turnover and improving their satisfaction and loyalty can also reduce customer defection and maintain or increase profits. The purpose of this paper is to put forth an argument that to measure customer service quality is not only an important strategic approach, but is a critical and intertwined link to organizational commitment, communication, and employee satisfaction by improving and maintaining high standards of consistent service quality delivery. This strategic approach pulls together many previously tested models into a single workable assessment and feedback tool, with a particular focus on employee training, by establishing a strategic and measurable benchmarking index for continual monitoring and operational improvement.

  18. The Three-Dimensional Approach of Total Quality Management, an Essential Strategic Option for Business Excellence

    Directory of Open Access Journals (Sweden)

    Armenia Androniceanu

    2017-02-01

    Full Text Available In a complex and dynamic business environment, managers widely appeal to modern methods and techniques that would help them cope with the competition and offer their customers new, attractive, good quality products and services and at competitive prices. In this context, total quality management is a viable and sustainable option that can systematically contribute to the consolidation of the capacity of organizations. The aim of this paper was to put forth a three-dimensional approach of total quality management and provide some concrete action ways through which organizations in Romania that implement total or partial quality management integrated systems would produce significant competitive advantages. The main research methods used were: the questionnaire, document analysis, applications offered by Word and Excel and the Statistical Package for Social Sciences, one of the most complete software packages with which we calculated means and standard deviations and determined and analysed correlations between variables and various quality parameters. In this research, have been identified the main key success factors, the vulnerabilities and weaknesses of the systems, their causes and the necessary changes through which the threedimensional approach of total quality management could become a preferred strategic option with a major positive impact upon business excellence. The most important results obtained are a three-dimensional approach of the Total Quality Management and a substantial number of certain proposals for the Romanian firms in order to achieve business excellence.

  19. An Algebraic Approach to Form Factors

    OpenAIRE

    Niedermaier, M. R.

    1994-01-01

    An associative $*$-algebra is introduced (containing a $TTR$-algebra as a subalgebra) that implements the form factor axioms, and hence indirectly the Wightman axioms, in the following sense: Each $T$-invariant linear functional over the algebra automatically satisfies all the form factor axioms. It is argued that this answers the question (posed in the functional Bethe ansatz) how to select the dynamically correct representations of the $TTR$-algebra. Applied to the case of integrable QFTs w...

  20. An Emerge Approach in Inter Cluster Similarity for Quality Clusters

    Directory of Open Access Journals (Sweden)

    H. Venkateswara Reddy

    2013-04-01

    Full Text Available Relationship between the datasets is one most important issue in recent years. The recent methods are based mostly on the numerical data, but these methods are not suitable for real time data such as web pages, business transactions etc., which are known as Categorical data. It is difficult to find relationship in categorical data. In this paper, a new approach is proposed for finding the relationshipbetween the categorical data, hence to find relationship between the clusters. The main aim is to identify the quality clusters based on the relationship between clusters. If there is no relationship between clusters then those clusters are treated as quality clusters.

  1. Quality Factor for the Hadronic Calorimeter in High Luminosity Conditions

    CERN Document Server

    Balabram, LE; The ATLAS collaboration; Filho, LM

    2014-01-01

    The Tile Calorimeter (TileCal) is the central section of the hadronic calorimeter of ATLAS experiment and has about 10,000 eletronic channels. An Optimal Filter (OF) has been used to estimate the energy sampled by the calorimeter and applies a Quality Factor (QF) for signal acceptance. An approach using Matched Filter (MF) has also been pursued. In order to cope with the luminosity rising foreseen for LHC operation upgrade, different algorithms have been developed. Among them, the Constrained Optimal Filter (COF) is showing good capacity in handling such luminosity rise by using a deconvolution technique, which revocers physics signals from out of time pile up. When pile up noise is low, COF switches to MF estimator for optimal performance. Currently, the OF measure for signal acceptance is implemented through a chi-square test. At a low-muninosity scenario, such QF measure has been used as a way to describe how the acquired singal is compatible to the pulse shape pattern. However, at high-luminosity conditio...

  2. High quality factor, fully switchable terahertz superconducting metasurface

    Energy Technology Data Exchange (ETDEWEB)

    Scalari, G., E-mail: scalari@phys.ethz.ch; Maissen, C.; Faist, J. [Institute of Quantum Electronics, Eidgenössische Technische Hochschule Zürich (Switzerland); Cibella, S.; Leoni, R. [Istituto di Fotonica e Nanotecnologie (IFN), CNR, via Cineto Romano 42, 00156 Rome (Italy)

    2014-12-29

    We present a complementary THz metasurface realised with Niobium thin film which displays a quality factor Q = 54 and a fully switchable behaviour as a function of the temperature. The switching behaviour and the high quality factor are due to a careful design of the metasurface aimed at maximising the ohmic losses when the Nb is above the critical temperature and minimising the radiative coupling. The superconductor allows the operation of the cavity with high Q and the use of inductive elements with a high aspect ratio. Comparison with three dimensional finite element simulations highlights the crucial role of the inductive elements and of the kinetic inductance of the Cooper pairs in achieving the high quality factor and the high field enhancement.

  3. Correlation study among water quality parameters an approach to water quality management.

    Science.gov (United States)

    Sinha, D K; Rastogi, G K; Kumar, R; Kumar, N

    2009-04-01

    To find out an approach to water quality management through correlation studies between various water quality parameters, the statistical regression analysis for six data points of underground drinking water of different hand pumps at J. P. Nagar was carried out. The comparison of estimated values with W.H.O drinking water standards revealed that water of the study area is polluted with reference to a number of physico-chemical parameters studied. Regression analysis suggests that conductivity of underground water is found to be significantly correlated with eight out of twelve water quality parameters studied. It may be suggested that the underground drinking water quality at J. P. Nagar can be checked very effectively by controlling the conductivity of water. The present study may be treated one step forward towards the water quality management.

  4. A Systems Engineering Approach to Quality Assurance for Aerospace Testing

    Science.gov (United States)

    Shepherd, Christena C.

    2015-01-01

    On the surface, it appears that AS91001 has little to say about how to apply a Quality Management System (QMS) to major aerospace test programs (or even smaller ones). It also appears that there is little in the quality engineering Body of Knowledge (BOK)2 that applies to testing, unless it is nondestructive examination (NDE), or some type of lab or bench testing associated with the manufacturing process. However, if one examines: a) how the systems engineering (SE) processes are implemented throughout a test program; and b) how these SE processes can be mapped to the requirements of AS9100, a number of areas for involvement of the quality professional are revealed. What often happens is that quality assurance during a test program is limited to inspections of the test article; what could be considered a manufacturing al fresco approach. This limits the quality professional and is a disservice to the programs and projects, since there are a number of ways that quality can enhance critical processes, and support efforts to improve risk reduction, efficiency and effectiveness.

  5. Project quality management critical success factors for buildings

    CERN Document Server

    Low, Sui Pheng

    2014-01-01

    The book presents the development of the Construction Quality Assessment System (CONQUAS), Singapore’s de facto quality performance measurement system, explains the application of the Quality Management System (QMS) to manage CONQUAS and identifies 33 critical success factors (CSFs) for achieving high CONQUAS scores. Through CONQUAS, the reader benefits from understanding how the Singapore government developed and implemented the first objective system for measuring what many building professionals have perceived to be elusive quality standards in the construction industry. The book presents both the theoretical concepts as well as the practical aspects to achieving strategic Project Quality Management that is anchored on the CSFs to building best practices. To realistically reflect the practical aspects and challenging issues faced by stakeholders in the construction industry, questionnaire surveys were conducted with building professionals to distinguish the importance level and extent of adoption of the ...

  6. A Method to Estimate Shear Quality Factor of Hard Rocks

    Science.gov (United States)

    Wang, Xin; Cai, Ming

    2017-07-01

    Attenuation has a large influence on ground motion intensity. Quality factors are used to measure wave attenuation in a medium and they are often difficult to estimate due to many factors such as the complex geology and underground mining environment. This study investigates the effect of attenuation on seismic wave propagation and ground motion using an advanced numerical tool—SPECFEM2D. A method, which uses numerical modeling and site-specific scaling laws, is proposed to estimate the shear quality factor of hard rocks in underground mines. In the numerical modeling, the seismic source is represented by a moment tensor model and the considered medium is isotropic and homogeneous. Peak particle velocities along the strongest wave motion direction are compared with that from a design scaling law. Based on the field data that were used to derive a semi-empirical design scaling law, it is demonstrated that a shear quality factor of 60 seems to be a representative for the hard rocks in deep mines to consider the attenuation effect of seismic wave propagation. Using the proposed method, reasonable shear quality factors of hard rocks can be obtained and this, in turn, will assist accurate ground motion determination for mine design.

  7. Process Approach to Determining Quality Inspection Deployment Product Overview

    Science.gov (United States)

    2015-05-07

    Manual Inspection covers10-20% of parts not covered by the machine Example ICT via Flying Probe U.S. SPACE PROGRAM MISSION ASSURANCE IMPROVEMENT...Identified part types and applications where ICT not able to capture all issues ROI • Performed study for purchasing unit vs. outsourcing • Identified...Bold – co-leads SME Team Approved Electronically by: AEROSPACE REPORT NO. TOR-2015-02542 Process Approach to Determining Quality Inspection Deployment

  8. Human Factors in Software Development Processes: Measuring System Quality

    DEFF Research Database (Denmark)

    Abrahão, Silvia; Baldassarre, Maria Teresa; Caivano, Danilo

    2016-01-01

    Software Engineering and Human-Computer Interaction look at the development process from different perspectives. They apparently use very different approaches, are inspired by different principles and address different needs. But, they definitively have the same goal: develop high quality software...

  9. Learning Approaches, Demographic Factors to Predict Academic Outcomes

    Science.gov (United States)

    Nguyen, Tuan Minh

    2016-01-01

    Purpose: The purpose of this paper is to predict academic outcome in math and math-related subjects using learning approaches and demographic factors. Design/Methodology/Approach: ASSIST was used as the instrumentation to measure learning approaches. The study was conducted in the International University of Vietnam with 616 participants. An…

  10. HSE management excellence: a Human Factors approach

    Directory of Open Access Journals (Sweden)

    Roberto Theobald

    2007-04-01

    Full Text Available Present work discusses the integration of Human Factors in Health, Safety and Enviroment(HSE Management System allowing it as a way of checking the progress obtained, therebyminimizing the efforts and maximizing the result. A bibliographical research was carried outon the theoretical elements of the theme. As a result of this work, a proposal “conceptualstructure” for the integration of “Humais Factors” with the HSE management system ofAssociation of Oil & Gas Produces was presented.

  11. [Risk factors for cesarean section: epidemiologic approach].

    Science.gov (United States)

    Trujillo Hernández, B; Tene Pérez, C E; Ríos Silva, M

    2000-07-01

    The increase in frequency of cesareans that has been noted through 70's, not diminished--like it was expected--perinatal morbidity and mortality. The most important indications to cesarean are distocias, previous cesarean and fetal stress. In 1998 frequency of cesarean deliveries in our hospital was 35% of the pregnancy attended. The claim of this study was to determine risks factors to cesarean in our hospital. A case-control study was performed, selecting 165 cases (cesareans) and 328 controls (via vaginal). It was determined OR of the risks factors and atribuible fraction. Data were analyzed by X2. The most important indications to cesarean delivery were: distocias (39%, n = 64); previous cesarean (23%, n = 41) and fetal stress (11%, n = 21). There was not significative differences in age, height and rupture membrane time in both groups. History of cesarean delivery gave major risk to another surgical intervention (OR = 12.7, p = < 0.0001, atribuible fraction 92%). Nuliparous (OR = 6.6, p < 0.00000, atribuible fraction 85%), second gestation (OR = 1.8, p = 0.002) or history of abortion (OR = 1.8, p = 0.04) were factors mainly associated to cesarean delivery. We concluded that the precise 'medications of this surgical intervention specially in nuliparous or previous cesarean delivery cases must be replanteated to diminish its elevated frequency.

  12. Neutrons in proton pencil beam scanning: parameterization of energy, quality factors and RBE

    Science.gov (United States)

    Schneider, Uwe; Hälg, Roger A.; Baiocco, Giorgio; Lomax, Tony

    2016-08-01

    The biological effectiveness of neutrons produced during proton therapy in inducing cancer is unknown, but potentially large. In particular, since neutron biological effectiveness is energy dependent, it is necessary to estimate, besides the dose, also the energy spectra, in order to obtain quantities which could be a measure of the biological effectiveness and test current models and new approaches against epidemiological studies on cancer induction after proton therapy. For patients treated with proton pencil beam scanning, this work aims to predict the spatially localized neutron energies, the effective quality factor, the weighting factor according to ICRP, and two RBE values, the first obtained from the saturation corrected dose mean lineal energy and the second from DSB cluster induction. A proton pencil beam was Monte Carlo simulated using GEANT. Based on the simulated neutron spectra for three different proton beam energies a parameterization of energy, quality factors and RBE was calculated. The pencil beam algorithm used for treatment planning at PSI has been extended using the developed parameterizations in order to calculate the spatially localized neutron energy, quality factors and RBE for each treated patient. The parameterization represents the simple quantification of neutron energy in two energy bins and the quality factors and RBE with a satisfying precision up to 85 cm away from the proton pencil beam when compared to the results based on 3D Monte Carlo simulations. The root mean square error of the energy estimate between Monte Carlo simulation based results and the parameterization is 3.9%. For the quality factors and RBE estimates it is smaller than 0.9%. The model was successfully integrated into the PSI treatment planning system. It was found that the parameterizations for neutron energy, quality factors and RBE were independent of proton energy in the investigated energy range of interest for proton therapy. The pencil beam algorithm has

  13. Simulating ensembles of source water quality using a K-nearest neighbor resampling approach.

    Science.gov (United States)

    Towler, Erin; Rajagopalan, Balaji; Seidel, Chad; Summers, R Scott

    2009-03-01

    Climatological, geological, and water management factors can cause significant variability in surface water quality. As drinking water quality standards become more stringent, the ability to quantify the variability of source water quality becomes more important for decision-making and planning in water treatment for regulatory compliance. However, paucity of long-term water quality data makes it challenging to apply traditional simulation techniques. To overcome this limitation, we have developed and applied a robust nonparametric K-nearest neighbor (K-nn) bootstrap approach utilizing the United States Environmental Protection Agency's Information Collection Rule (ICR) data. In this technique, first an appropriate "feature vector" is formed from the best available explanatory variables. The nearest neighbors to the feature vector are identified from the ICR data and are resampled using a weight function. Repetition of this results in water quality ensembles, and consequently the distribution and the quantification of the variability. The main strengths of the approach are its flexibility, simplicity, and the ability to use a large amount of spatial data with limited temporal extent to provide water quality ensembles for any given location. We demonstrate this approach by applying it to simulate monthly ensembles of total organic carbon for two utilities in the U.S. with very different watersheds and to alkalinity and bromide at two other U.S. utilities.

  14. A hybrid fuzzy MCDM approach to maintenance Quality Function Deployment

    Directory of Open Access Journals (Sweden)

    Davy George Valavi

    2015-01-01

    Full Text Available Maintenance Quality Function Deployment (MQFD is a model, which enhances the synergic power of Quality Function Deployment (QFD and Total Productive Maintenance (TPM. One of the crucial and important steps during the implementation of MQFD is the determination of the importance or weightages of the critical factors (CF and sub factors (SF. The CFs and SFs have to be compared precisely for the successful implementation of MQFD. The crisp pair-wise comparison in the conventional Analytical Hierarchy Process (AHP may be insufficient to determine the degree of weightage of CFs and SFs where vagueness and uncetainties are associated. In this paper, a modification of AHP based MQFD by incorporating fuzzy operations is proposed, which can improve the accuracy of determination of the weightages. A case study showing the applicability of this method is illustrated in this paper.

  15. Muscle quality in aging: a multi-dimensional approach to muscle functioning with applications for treatment.

    Science.gov (United States)

    Fragala, Maren S; Kenny, Anne M; Kuchel, George A

    2015-05-01

    Aging is often accompanied by declines in physical functioning which impedes older adults' quality of life, sense of independence, and ability to perform daily tasks. Age-related decreases in skeletal muscle quantity, termed sarcopenia, have traditionally been blamed for these physical decrements. However, recent evidence suggests that the quality of muscle tissue may be more functionally relevant than its quantity. 'Muscle quality' has been emerging as a means to elucidate and describe the intricate intramuscular changes associated with muscle performance in the context of aging and sarcopenia. While muscle quality has most commonly been defined in terms of muscle composition or relative strength, at the core, muscle quality really describes muscle's ability to function. Skeletal muscle displays a strong structure-function relationship by which several architectural characteristics factor into its functional capacity. This review describes the structural, physiological, and functional determinants of muscle quality at the tissue and cellular level, while also introducing other novel parameters such as sarcomere spacing and integrity, circulating biomarkers, and the muscle quality index. Muscle qualitative features are described from the perspective of how physical exercise may improve muscle quality in older adults. This broad, multidimensional perspective of muscle quality in the context of aging and sarcopenia offers comprehensive insights for consideration and integration in developing improved prognostic tools for research and clinical care, while also promoting translational approaches to the design of novel targeted intervention strategies designed to maintain function and mobility into late life.

  16. Automatic tuning of quality factors for VHF CMOS filters

    NARCIS (Netherlands)

    Nauta, Bram; Seevinck, Evert

    1990-01-01

    A VHF transconductance-C filter technique with automatic tuning of the quality factors and the cutoff frequency, based on a voltage controlled oscillator (VCO), is presented. The Q-tuning circuit is very simple and contains no signal carrying nodes, resulting in a well-controlled Q up to very high f

  17. Microwave microstrip resonators tuning without quality factor deterioration

    Directory of Open Access Journals (Sweden)

    P. Y. Serhienko

    2014-04-01

    Full Text Available Stub and ring resonators with resonance frequency micromechanical tuning are presented. Benefits and main differences of micromechanical resonance frequency tuning method from other methods are shown. Normalized dependences of effective permittivity on normalized air gap values for various microstrip line electrode width to substrate height ratios are obtained. Effective permittivity analytical formulas for the case of infinitely wide electrodes are derived. Calculated and experimental dependences of resonance frequency on air gap value and stub experimental unloaded quality factor dependences are given. Air gap influence on resonance frequency value depending on substrate permittivity is shown in terms of the resonance frequency sensitivity. Error estimation for measured experimental data is presented. Adding tunable heterogeneity between the microstrip resonator signal electrode and the substrate provides not only the resonance frequency tuning but preserves unloaded quality factor. The preservation of the unloaded quality factor during the resonance frequency tuning achieved due to the metal and dielectric loss reduction. Air gap doesn’t have dissipative losses and has permittivity of one, which makes it the best solution for unloaded quality factor preservation. Another important conclusion is that insertion of the air heterogeneity reduces values of dielectric and metal losses arising when substrates with high permittivity are used. For dielectric loss reduction, it is important to maintain low ratio of microstrip line width to substrate height. In contrast to dielectric losses for metal loss reduction the ratio of microstrip line width to substrate height should be high. However, that ratio is limited by impedance permissible range.

  18. DEPENDENCE RELATIONSHIP BETWEEN THE CRITICAL QUALITY FACTORS AND SOCIAL IMPACT

    Directory of Open Access Journals (Sweden)

    José Álvarez García

    2014-10-01

    Full Text Available This paper shows the results of the empirical study conducted in 186 tourist accommodation businesses in Spain certified under the “Q for Tourist Quality”, own System Quality Management. It was raised with the purpose of analyzing the structure of the relationship between critical quality factors and results-social impact, how they operate and the level of their influence on obtaining these results within the company. Starting from a deep theoretical revision we propose a theoretical model together with the hypotheses to be tested, and we proceed to validation using the technique of Structural Equation Models. The results obtained show that companies wishing to improve their social impact should take into account that leadership is the most important factor to achieve it. Leadership indirectly affects the social impact through its influence on alliances and resources, quality policy/planning, personnel management and learning.

  19. A Novel Approach for Estimating Truck Factors

    OpenAIRE

    Avelino, Guilherme; Passos, Leonardo; Hora, Andre; Valente, Marco Tulio

    2016-01-01

    Truck Factor (TF) is a metric proposed by the agile community as a tool to identify concentration of knowledge in software development environments. It states the minimal number of developers that have to be hit by a truck (or quit) before a project is incapacitated. In other words, TF helps to measure how prepared is a project to deal with developer turnover. Despite its clear relevance, few studies explore this metric. Altogether there is no consensus about how to calculate it, and no suppo...

  20. Simultaneous measurement of quality factor and wavelength shift by phase shift microcavity ring down spectroscopy

    CERN Document Server

    Cheema, M Imran; Hayat, Ahmad A; Peter, Yves-Alain; Armani, Andrea M; Kirk, Andrew G

    2012-01-01

    Optical resonant microcavities with ultra high quality factors are widely used for biosensing. Until now, the primary method of detection has been based upon tracking the resonant wavelength shift as a function of biological events. One of the sources of noise in all resonant-wavelength shift measurements is the noise due to intensity fluctuations of the laser source. An alternative approach is to track the change in the quality factor of the optical cavity by using phase shift cavity ring down spectroscopy, a technique which is insensitive to the intensity fluctuations of the laser source. Here, using biotinylated microtoroid resonant cavities, we show simultaneous measurement of the quality factor and the wavelength shift by using phase shift cavity ring down spectroscopy. These measurements were performed for disassociation phase of biotin-streptavidin reaction. We found that the disassociation curves are in good agreement with the previously published results. Hence, we demonstrate not only the applicatio...

  1. The Quality of Life and relevant Approaches based on Capabilities and Functionalities

    Directory of Open Access Journals (Sweden)

    Matei Șimandan

    2014-12-01

    Full Text Available Recent research regarding the quality of life developed different approaches concerning the use of objective and subjective indicators, as well as the relevance of hypotheses, propositions and methods of analysis or of evaluation. Starting from the conceptual difficulties regarding the term of ‘quality of life’, this article focuses upon the contributions of Amartya Sen on the relationships between resources, liberties, capabilities, functionalities and human development. A separate section attempts to capture the shift of accent from the approaches of a quantitative type towards those of a qualitative type, founded on capabilities, functionalities, and the factors of conversion of resources into elements of quality of subjective life. The following sections are consecrated to the contributions to the development of the model proposed by Amartya Sen and to the reception of this model by a few specialists in the field, as well as to its relevance within scientific research and the foundation of public policies.

  2. Factor Analysis in Assessing the Research Methodology Quality of Systematic Reviews

    Directory of Open Access Journals (Sweden)

    Andrada Elena URDA-CÎMPEAN

    2011-12-01

    Full Text Available Introduction: Many high quality systematic reviews available from medical journals, data bases and other electronic sources differ in quality and provide different answers to the same question. The literature recommended the use of a checklist type approach, which exceeds many of the problems associated with measurements. Aim: This study proposes to identify in a checklist type approach the most commonly used factors (from a methodological point of view in assessing the quality of systematic reviews, and then mirror the actual stage of medical writing. We want to analyze the factors’ occurrence and / or their development in the text and in the abstract of systematic reviews published in 2011. Methods: The present study randomly selected only free full text systematic reviews published in 2011, systematic reviews found in Pubmed and in Cochrane Database. The most commonly used factors were identified in PRISMA statement and quality measurement tools. Results: The evaluated systematic reviews mentioned or developed several of the factors studied. Only 78% of the papers surveyed have used the correct IMRAD format and 59% of them have mentioned the sample size used. The correspondence between the content of the paper and its abstract is summarized in the proportion of 54.63% and 51.85% for the two sets of factors, and it can lead to scarce appreciation of the article provided that only abstracts are read. Conclusions: Researchers do not properly take into consideration scientific articles and assessment tools used for quality evaluation. They should place more value over methodological factors which help assess systematic review quality, while journals form the only party who can enforce quality standards in medical writing.

  3. Factors influencing quality of bowel preparation for colonoscopy.

    Science.gov (United States)

    Romero, Ronald V; Mahadeva, Sanjiv

    2013-02-16

    Recent technological advances in colonoscopy have led to improvements in both image enhancement and procedural performance. However, the utility of these technological advancements remain dependent on the quality of bowel preparation during colonoscopy. Poor bowel preparation has been shown to be associated with lower quality indicators of colonoscopy performance, such as reduced cecal intubation rates, increased patient discomfort and lower adenoma detection. The most popular bowel preparation regimes currently used are based on either Polyethylene glycol-electrolyte, a non-absorbable solution, or aqueous sodium phosphate, a low-volume hyperosmotic solution. Statements from various international societies and several reviews have suggested that the efficacy of bowel preparation regimes based on both purgatives are similar, although patients' compliance with these regimes may differ somewhat. Many studies have now shown that factors other than the type of bowel preparation regime used, can influence the quality of bowel preparation among adult patients undergoing colonoscopy. These factors can be broadly categorized as either patient-related or procedure-related. Studies from both Asia and the West have identified patient-related factors such as an increased age, male gender, presence of co-morbidity and socio-economic status of patients to be associated with poor bowel preparation among adults undergoing routine out-patient colonoscopy. Additionally, procedure-related factors such as adherence to bowel preparation instructions, timing of bowel purgative administration and appointment waiting times for colonoscopy are recognized to influence the quality of colon cleansing. Knowledge of these factors should aid clinicians in modifying bowel preparation regimes accordingly, such that the quality of colonoscopy performance and delivery of service to patients can be optimised.

  4. Management of Highway Projects in Egypt through Identifying Factors Influencing Quality Performance

    Directory of Open Access Journals (Sweden)

    Ahmed Ebrahim Abu El-Maaty

    2016-01-01

    Full Text Available While project management success focuses upon the processes and the successful accomplishments of cost and time objectives, product success deals with the quality of the final product. Recently, quality of the constructed highway has been considered highly important reason for the pavement response and its design life. The main objective of this paper is to improve the management of highway projects in Egypt by determining the most important factors influencing the quality performance of this industry. In total, 39 factors that may influence the quality of highway projects have been defined through a detailed literature review. The factors are tabulated in a questionnaire form, which is sent out to 13 owners of divided highways, 27 owners of regional roads, and 15 consultants. The analysis of the respondents’ perspectives using fuzzy triangle approach shows that the most important factors affecting the quality are availability of experienced staff in the owner’s and contractor’s teams during the project execution; efficiency of the owner’s inspection team; clarity of responsibilities and roles for each owner, consultant, and contractor; pavement which is not designed according to the regional conditions (e.g., soil type, temperature, and traffic volume; and asphalt quality and type used in the construction process.

  5. A Complex Systems Science Approach to Healthcare Costs and Quality

    CERN Document Server

    Bar-Yam, Yaneer Bar-Yam with Shlomiya; Cohen, Nancy; Gard-Murray, Alexander S; Harte, Helen P; Leykum, Luci

    2012-01-01

    There is a mounting crisis in delivering affordable healthcare in the US. For decades, key decision makers in the public and private sectors have considered cost-effectiveness in healthcare a top priority. Their actions have focused on putting a limit on fees, services, or care options. However, they have met with limited success as costs have increased rapidly while the quality isn't commensurate with the high costs. A new approach is needed. Here we provide eight scientifically-based steps for improving the healthcare system. The core of the approach is promoting the best use of resources by matching the people and organization to the tasks they are good at, and providing the right incentive structure. Harnessing costs need not mean sacrificing quality. Quality service and low costs can be achieved by making sure the right people and the right organizations deliver services. As an example, the frequent use of emergency rooms for non-emergency care demonstrates the waste of resources of highly capable indivi...

  6. A comprehensive approach to quality management of intensive care services.

    Science.gov (United States)

    Hariharan, Seetharaman; Dey, Prasanta Kumar

    2010-01-01

    The purpose of this paper is to develop a comprehensive framework for improving intensive care unit performance. The study introduces a quality management framework by combining cause and effect diagram and logical framework. An intensive care unit was identified for the study on the basis of its performance. The reasons for not achieving the desired performance were identified using a cause and effect diagram with the stakeholder involvement. A logical framework was developed using information from the cause and effect diagram and a detailed project plan was developed. The improvement projects were implemented and evaluated. Stakeholders identified various intensive care unit issues. Managerial performance, organizational processes and insufficient staff were considered major issues. A logical framework was developed to plan an improvement project to resolve issues raised by clinicians and patients. Improved infrastructure, state-of-the-art equipment, well maintained facilities, IT-based communication, motivated doctors, nurses and support staff, improved patient care and improved drug availability were considered the main project outputs for improving performance. The proposed framework is currently being used as a continuous quality improvement tool, providing a planning, implementing, monitoring and evaluating framework for the quality improvement measures on a sustainable basis. The combined cause and effect diagram and logical framework analysis is a novel and effective approach to improving intensive care performance. Similar approaches could be adopted in any intensive care unit. The paper focuses on a uniform model that can be applied to most intensive care units.

  7. Factors affecting quality and safety of fresh-cut produce.

    Science.gov (United States)

    Francis, G A; Gallone, A; Nychas, G J; Sofos, J N; Colelli, G; Amodio, M L; Spano, G

    2012-01-01

    The quality of fresh-cut fruit and vegetable products includes a combination of attributes, such as appearance, texture, and flavor, as well as nutritional and safety aspects that determine their value to the consumer. Nutritionally, fruit and vegetables represent a good source of vitamins, minerals, and dietary fiber, and fresh-cut produce satisfies consumer demand for freshly prepared, convenient, healthy food. However, fresh-cut produce deteriorates faster than corresponding intact produce, as a result of damage caused by minimal processing, which accelerates many physiological changes that lead to a reduction in produce quality and shelf-life. The symptoms of produce deterioration include discoloration, increased oxidative browning at cut surfaces, flaccidity as a result of loss of water, and decreased nutritional value. Damaged plant tissues also represent a better substrate for growth of microorganisms, including spoilage microorganisms and foodborne pathogens. The risk of pathogen contamination and growth is one of the main safety concerns associated with fresh-cut produce, as highlighted by the increasing number of produce-linked foodborne outbreaks in recent years. The pathogens of major concern in fresh-cut produce are Listeria monocytogenes, pathogenic Escherichia coli mainly O157:H7, and Salmonella spp. This article describes the quality of fresh-cut produce, factors affecting quality, and various techniques for evaluating quality. In addition, the microbiological safety of fresh-cut produce and factors affecting pathogen survival and growth on fresh-cut produce are discussed in detail.

  8. A trait based approach to defining valued mentoring qualities

    Science.gov (United States)

    Pendall, E.

    2012-12-01

    Graduate training in the sciences requires strong personal interactions among faculty, senior lab members and more junior members. Within the lab-group setting we learn to frame problems, to conduct research and to communicate findings. The result is that individual scientists are partly shaped by a few influential mentors. We have all been influenced by special relationships with mentors, and on reflection we may find that certain qualities have been especially influential in our career choices. In this presentation I will discuss favorable mentoring traits as determined from an informal survey of scientists in varying stages of careers and from diverse backgrounds. Respondents addressed questions about traits they value in their mentors in several categories: 1) personal qualities such as approachability, humor and encouragement; background including gender, ethnicity, and family status; 2) scientific qualities including discipline or specialization, perceived stature in discipline, seniority, breadth of perspective, and level of expectations; and 3) community-oriented qualities promoted by mentors, such as encouraging service contributions and peer-mentoring within the lab group. The results will be compared among respondents by gender, ethnicity, stage of career, type of work, and subdiscipline within the broadly defined Biogeoscience community. We hope to contribute to the growing discussion on building a diverse and balanced scientific workforce.

  9. Short Term Air Quality Forecast Using Data Driven Approaches

    Directory of Open Access Journals (Sweden)

    Shruti S. Tikhe

    2014-01-01

    Full Text Available Predicting air quality is a challenge, when there are uncertainties involved in the availability as well as accuracy of the desired data. Most of the developing countries including India often have no formalized forecasting approach. Little data (which may be of suspect quality and inadequate institutional structure to support data collection are the main concerns. Present study suggests a forecasting tool that is seldom used in the field of air quality forecasting; but is a proven robust technique. Thirty six models have been developed with Genetic Programming (GP and Artificial Neural Networks (ANN considering daily average concentrations of meteorological parameters as well as pollutant concentrations spanning from 2005-2008 for one of the most polluted metropolitan city of India. The models are specific to cases when all the significant input parameters ( data are not available because of various reasons. ANN is used as a benchmarking tool for estimation and prediction of air quality and the results are compared with GP .Performance of all the models has been assessed using r (correlation coefficient, RMSE (root mean square error & d (d statistics.Compared to ANN, GP models seem to work well in all cases considered because of unavailability of data and have an advantage of pollution forecasting equation generated by the model. These equations can be of help for real time forecasting.

  10. Accreditation and quality approach in operating theatre departments: the French approach.

    Science.gov (United States)

    Soudée, M

    2005-01-01

    Since 1996, French health establishments are subjected to a process of evaluating the quality of care, called "accreditation". This process was controlled by ANAES, which, after January 1st, 2005 became the Haute Autorité de Santé (HAS). The accreditation is characterized by a dual process of self-assessment and external audit, leading to four levels of accreditation. In spite of requiring a time-consuming methodology, this approach provides an important means of consolidating the development of the quality approach and re-stimulating the compliance of establishments with standards of safety and vigilance. The professional teams of many French operating theatre departments have been able to use the regulatory and restricting framework of accreditation to organize quality approaches specific to the operative system, supported by the organizational structures of the department such as the operating suite committee, departmental boards and the steering group. Based on quality guidelines including a commitment from the manager and operating suite committee, as well as a quality flow chart and a quality system, these teams describe the main procedures for running the operating theatre. They also organize the follow-up of incidents and undesirable events, along with the risks and points to watch. Audits of the operative system are planned on a regular basis. The second version of the accreditation process considerably reinforces the assessment of professional practices by evaluating the relevance, the risks and the methods of managing care for pathologies. It will make it possible to implement assessments of the health care provided by operating theatre departments and will reinforce the importance of search for quality.

  11. The study of surgical image quality evaluation system by subjective quality factor method

    Science.gov (United States)

    Zhang, Jian J.; Xuan, Jason R.; Yang, Xirong; Yu, Honggang; Koullick, Edouard

    2016-03-01

    GreenLightTM procedure is an effective and economical way of treatment of benign prostate hyperplasia (BPH); there are almost a million of patients treated with GreenLightTM worldwide. During the surgical procedure, the surgeon or physician will rely on the monitoring video system to survey and confirm the surgical progress. There are a few obstructions that could greatly affect the image quality of the monitoring video, like laser glare by the tissue and body fluid, air bubbles and debris generated by tissue evaporation, and bleeding, just to name a few. In order to improve the physician's visual experience of a laser surgical procedure, the system performance parameter related to image quality needs to be well defined. However, since image quality is the integrated set of perceptions of the overall degree of excellence of an image, or in other words, image quality is the perceptually weighted combination of significant attributes (contrast, graininess …) of an image when considered in its marketplace or application, there is no standard definition on overall image or video quality especially for the no-reference case (without a standard chart as reference). In this study, Subjective Quality Factor (SQF) and acutance are used for no-reference image quality evaluation. Basic image quality parameters, like sharpness, color accuracy, size of obstruction and transmission of obstruction, are used as subparameter to define the rating scale for image quality evaluation or comparison. Sample image groups were evaluated by human observers according to the rating scale. Surveys of physician groups were also conducted with lab generated sample videos. The study shows that human subjective perception is a trustworthy way of image quality evaluation. More systematic investigation on the relationship between video quality and image quality of each frame will be conducted as a future study.

  12. An approach to quality and security of supply for single-use bioreactors.

    Science.gov (United States)

    Barbaroux, Magali; Gerighausen, Susanne; Hackel, Heiko

    2014-01-01

    Single-use systems (also referred to as disposables) have become a huge part of the bioprocessing industry, which raised concern in the industry regarding quality and security of supply. Processes must be in place to assure the supply and control of outsourced activities and quality of purchased materials along the product life cycle. Quality and security of supply for single-use bioreactors (SUBs) are based on a multidisciplinary approach. Developing a state-of-the-art SUB-system based on quality by design (QbD) principles requires broad expertise and know-how including the cell culture application, polymer chemistry, regulatory requirements, and a deep understanding of the biopharmaceutical industry. Using standardized products reduces the complexity and strengthens the robustness of the supply chain. Well-established supplier relations including risk mitigation strategies are the basis for achieving long-term security of supply. Well-developed quality systems including change control approaches aligned with the requirements of the biopharmaceutical industry are a key factor in supporting long-term product availability. This chapter outlines the approach to security of supply for key materials used in single-use production processes for biopharmaceuticals from a supplier perspective.

  13. Factors influencing the biochemical markers for predicting mammalian oocyte quality.

    Science.gov (United States)

    Ola, Safiriyu Idowu; Sun, Qing-Yuan

    2012-01-01

    The need for accurate selection of the best oocytes for in vitro fertilization protocols and thus, production of embryos has driven the search for oocyte quality markers from morphological criteria to biochemical parameters. Current studies are focused on the biochemical constituents of the follicular fluid and gene expression profiling of the cumulus cells. These parameters are, however, affected by factors that must be considered before making a judgment of the oocyte's quality. These includes factors such as the type of hormonal stimulation protocol, age of oocyte donor and heat stress on the donor, all of which have been reported to influence the concentrations of many hormones, apolipoproteins, metabolites, fatty acids and growth factors in the follicular fluid and the expression of several genes in the cumulus cells. Another important point to note is species variation in the response to these extraneous influences, which thus calls for species targeted investigations. As reports are still scanty and investigations assumed to be very keen, we employed this review paper to bring attention of researchers and clinicians to those factors that may come to bear on the outcome of their investigations on oocyte and embryo quality.

  14. A Dynamic Bayesian Approach to Computational Laban Shape Quality Analysis

    Directory of Open Access Journals (Sweden)

    Dilip Swaminathan

    2009-01-01

    kinesiology. LMA (especially Effort/Shape emphasizes how internal feelings and intentions govern the patterning of movement throughout the whole body. As we argue, a complex understanding of intention via LMA is necessary for human-computer interaction to become embodied in ways that resemble interaction in the physical world. We thus introduce a novel, flexible Bayesian fusion approach for identifying LMA Shape qualities from raw motion capture data in real time. The method uses a dynamic Bayesian network (DBN to fuse movement features across the body and across time and as we discuss can be readily adapted for low-cost video. It has delivered excellent performance in preliminary studies comprising improvisatory movements. Our approach has been incorporated in Response, a mixed-reality environment where users interact via natural, full-body human movement and enhance their bodily-kinesthetic awareness through immersive sound and light feedback, with applications to kinesiology training, Parkinson's patient rehabilitation, interactive dance, and many other areas.

  15. Optimized Quality Factor of Graphene Oxide-Reinforced PVC Nanocomposite

    Science.gov (United States)

    Joshi, Girish M.; Deshmukh, Kalim

    2014-04-01

    Graphene oxide (GO)-reinforced polyvinyl chloride (PVC) composite films were prepared by solution blending. The homogeneity of GO dispersion with PVC was confirmed by an optical microscope. Quality factor ( Q-factor) as a function of temperature (40-150 °C) was measured within a broadband frequency range of 50-35 MHz. The controlled GO loading demonstrates a crucial impact on the optimization of the Q-factor, resonance frequency ( f 0) and wide bandwidth. This nanocomposite may be well suited for electronic applications. The further development of GO-reinforced polymer nanocomposites based on an optimized Q-factor may result in a material for electromagnetic frequency radiation shields for radar and communication towers/devices.

  16. High Quality Factor Fano-Resonant All-Dielectric Metamaterials

    CERN Document Server

    Yang, Yuanmu; Briggs, Dayrl P; Valentine, Jason

    2014-01-01

    Fano-resonant plasmonic metamaterials and nanostructures have become a major focus of the nanophotonics fields over the past several years due their ability to produce high quality factor (Q-factor) resonances. The origin of such resonances is the interference between a broad and narrow resonance, ultimately allowing suppression of radiative damping. However, Fano-resonant plasmonic structures still suffer non-radiative damping due to Ohmic loss, ultimately limiting the achievable Q-factors to values less than 10. Here, we report experimental demonstration of Fano-resonant silicon-based metamaterials that have a response that mimics the electromagnetically induced transparency (EIT) found in atomic systems. Due to extremely low absorption loss, a record-high Q-factor of 306 was experimentally observed. Furthermore, the unit cell of the metamaterial was designed with a feed-gap which results in strong local field enhancement in the surrounding medium resulting in strong light-matter interaction. This allows th...

  17. Enhanced imaging of DNA via active quality factor control

    Science.gov (United States)

    Humphris, A. D. L.; Round, A. N.; Miles, M. J.

    2001-10-01

    Adsorption processes at single molecule level are of fundamental importance for the understanding and development of biomaterials. Atomic force microscopy (AFM) has played a critical role in this field due to its high resolution and ability to image in a liquid environment. We present a method that improves the dynamic force sensitivity and the resolution of a conventional AFM. This is achieved via a positive feedback loop that enhances the effective quality factor of the cantilever in a liquid environment to values in excess of 300, compared to a nominal value of ˜1. This active quality factor enhancement has been used to image DNA and an increase in the height of the molecule observed.

  18. Generalized beam quality factor of aberrated truncated Gaussian laser beams

    CSIR Research Space (South Africa)

    Mafusire, C

    2011-07-01

    Full Text Available factor of aberrated truncated Gaussian laser beams Cosmas Mafusire1,2 and Andrew Forbes1,2,* 1Council for Scientific and Industrial Research National Laser Centre, P.O. Box 395, Pretoria, South Africa 2School of Physics, University of Kwa... is verified experimentally by implementing aberrations as digital holograms in the laboratory. ? 2011 Optical Society of America OCIS codes: 140.3295, 080.1005, 120.5050. 1. INTRODUCTION The laser beam quality factor (M2) is a useful parameter...

  19. Integrated high quality factor lithium niobate microdisk resonators

    CERN Document Server

    Wang, Cheng; Lin, Zin; Atikian, Haig A; Venkataraman, Vivek; Huang, I-Chun; Stark, Peter; Lončar, Marko

    2014-01-01

    Lithium Niobate (LN) is an important nonlinear optical material. Here we demonstrate LN microdisk resonators that feature optical quality factor ~ 100,000, realized using robust and scalable fabrication techniques, that operate over a wide wavelength range spanning visible and near infrared. Using our resonators, and leveraging LN's large second order optical nonlinearity, we demonstrate on-chip second harmonic generation with a conversion efficiency of 0.109 W-1.

  20. Area Based Approach for Three Phase Power Quality Assessment in Clarke Plane

    Directory of Open Access Journals (Sweden)

    S. CHATTOPADHYAY

    2008-03-01

    Full Text Available This paper presents an area-based approach for electric power quality analysis. Some specific reference signals have been defined and areas formed by the real power system data with the reference signal have been calculated wherefrom contributions of fundamental waveform and harmonic components have been assessed separately. Active power, reactive power and total harmonic distortion factors have been measured. Clarke transformation technique has been used for analysis in three-phase system, which has reduced the computational effort to a great extent. Distortion factors of individual phase of a three-phase system have also been assessed.

  1. Improving the Optical Quality Factor of the WGM Resonator

    Science.gov (United States)

    Savchenkov, Anatoliy; Matsko, Andrey; Iltchenko, Vladimir

    2008-01-01

    Resonators usually are characterized with two partially dependent values: finesse (F) and quality factor (Q). The finesse of an empty Fabry-Perot (FP) resonator is defined solely by the quality of its mirrors and is calculated as F=piR(exp 1/2)/(1-R). The maximum up-to-date value of reflectivity R approximately equal to 1 - 1.6 x 10(exp -6) is achieved with dielectric mirrors. An FP resonator made with the mirrors has finesse F=1.9 x 10(exp 6). Further practical increase of the finesse of FP resonators is problematic because of the absorption and the scattering of light in the mirror material through fundamental limit on the reflection losses given by the internal material losses and by thermodynamic density fluctuations on the order of parts in 109. The quality factor of a resonator depends on both its finesse and its geometrical size. A one-dimensional FP resonator has Q=2 F L/lambda, where L is the distance between the mirrors and lambda is the wavelength. It is easy to see that the quality factor of the resonator is unlimited because L is unlimited. F and Q are equally important. In some cases, finesse is technically more valuable than the quality factor. For instance, buildup of the optical power inside the resonator, as well as the Purcell factor, is proportional to finesse. Sometimes, however, the quality factor is more valuable. For example, inverse threshold power of intracavity hyperparametric oscillation is proportional to Q(exp 2) and efficiency of parametric frequency mixing is proportional to Q(exp 3). Therefore, it is important to know both the maximally achievable finesse and quality factor values of a resonator. Whispering gallery mode (WGM) resonators are capable of achieving larger finesse compared to FP resonators. For instance, fused silica resonators with finesse 2.3 x 10(exp 6) and 2.8 x 10(exp 6) have been demonstrated. Crystalline WGM resonators reveal even larger finesse values, F=6.3 x 10(exp 6), because of low attenuation of light in the

  2. A Wavelet Approach to Estimate The Quality of Ground Parts

    Directory of Open Access Journals (Sweden)

    E. Rubio

    2012-03-01

    Full Text Available The manufacturing process of metal parts is subjected to machining instabilities that can degrade the surface finish quality and the reliability of products. Some instabilities are of transient nature and traditional inspection systems are unable to adequately estimate the grade of affectation in the finished parts. Time-frequency analyses are techniques that overcome these limitations and have recently been incorporated in special industry inspection equipment to improve the quality of the manufactured parts. Grinding is a process used to get high precision and very smooth surface in flat or cylindrical parts because of the target applications such as the automotive industry where the highest standards can be found. This paper reports a technique to estimate the quality of ground parts based on timefrequency transforms that are used to enhance the defects. This makes it easier to implement the technique for surface characterization in online pass/no-pass inspection machines. The fundamentals of the methodology are revised and the technique is applied to the identification of vibration marks in cylindrical ground rods. Results show that this approach identifies adequately imperfections of transient nature and it is able to estimate the extension and amplitude of the defects on the surface of the manufactured parts.

  3. Pharmaceutical product development: A quality by design approach.

    Science.gov (United States)

    Pramod, Kannissery; Tahir, M Abu; Charoo, Naseem A; Ansari, Shahid H; Ali, Javed

    2016-01-01

    The application of quality by design (QbD) in pharmaceutical product development is now a thrust area for the regulatory authorities and the pharmaceutical industry. International Conference on Harmonization and United States Food and Drug Administration (USFDA) emphasized the principles and applications of QbD in pharmaceutical development in their guidance for the industry. QbD attributes are addressed in question-based review, developed by USFDA for chemistry, manufacturing, and controls section of abbreviated new drug applications. QbD principles, when implemented, lead to a successful product development, subsequent prompt regulatory approval, reduce exhaustive validation burden, and significantly reduce post-approval changes. The key elements of QbD viz., target product quality profile, critical quality attributes, risk assessments, design space, control strategy, product lifecycle management, and continual improvement are discussed to understand the performance of dosage forms within design space. Design of experiments, risk assessment tools, and process analytical technology are also discussed for their role in QbD. This review underlines the importance of QbD in inculcating science-based approach in pharmaceutical product development.

  4. Pharmaceutical product development: A quality by design approach

    Science.gov (United States)

    Pramod, Kannissery; Tahir, M. Abu; Charoo, Naseem A.; Ansari, Shahid H.; Ali, Javed

    2016-01-01

    The application of quality by design (QbD) in pharmaceutical product development is now a thrust area for the regulatory authorities and the pharmaceutical industry. International Conference on Harmonization and United States Food and Drug Administration (USFDA) emphasized the principles and applications of QbD in pharmaceutical development in their guidance for the industry. QbD attributes are addressed in question-based review, developed by USFDA for chemistry, manufacturing, and controls section of abbreviated new drug applications. QbD principles, when implemented, lead to a successful product development, subsequent prompt regulatory approval, reduce exhaustive validation burden, and significantly reduce post-approval changes. The key elements of QbD viz., target product quality profile, critical quality attributes, risk assessments, design space, control strategy, product lifecycle management, and continual improvement are discussed to understand the performance of dosage forms within design space. Design of experiments, risk assessment tools, and process analytical technology are also discussed for their role in QbD. This review underlines the importance of QbD in inculcating science-based approach in pharmaceutical product development. PMID:27606256

  5. Developing a customer-driven approach to quality improvement systems.

    Science.gov (United States)

    Owad, W P

    1993-01-01

    The development of a DCP in the manner presented previously has allowed for a consistent definition of customer needs and expectations within a pharmacy service. By applying this approach it has allowed the department to address the controversies associated with the identification of key customers and has also allowed a balance to be achieved between internal and external forces. From our analysis it is clear that the pharmacy department has a critical role in establishing a customer service philosophy that is key to the overall success of the institution's quality goal. It is also clear that pharmacy services cannot truly be developed without a customer service philosophy central to their design and implementation. In an era where drug expenditures represent an ever-increasing portion of corporate budgets, the pharmacy's ability to deliver goods and services that are customer and quality focused will be critical to organizational survival. The time has come to put ego aside and critically analyze whether or not a quality service is being delivered that meets a true customer need.

  6. Information quality for PPC: analysis of influence factors and diagnosis method proposal

    Directory of Open Access Journals (Sweden)

    Eduardo Belmonte Möller

    2013-03-01

    Full Text Available One of the most important problems that companies have to face for Production Planning and Control (PPC is the lack of Information Quality (IQ to support the decision making process. In this context, determining which factors affect the IQ necessary for PPC is a key issue. This paper presents a case study that analyzes the main influence factors on IQ. Furthermore, this paper proposes a method to perform diagnosis about these influence factors in companies. To analyze the IQ influence factors, a classification based on the sociotechnical approach was used and a set of matrixes that relate the IQ influence factors with the different functional areas that support the PPC were proposed. Results enable to identify which are the main factors and the functional areas and processes that can be improved to increase the IQ for PPC. This paper presents also practical results that show how to drive an IQ diagnosis.

  7. Impairment-Factor-Based Audiovisual Quality Model for IPTV: Influence of Video Resolution, Degradation Type, and Content Type

    Directory of Open Access Journals (Sweden)

    Garcia MN

    2011-01-01

    Full Text Available This paper presents an audiovisual quality model for IPTV services. The model estimates the audiovisual quality of standard and high definition video as perceived by the user. The model is developed for applications such as network planning and packet-layer quality monitoring. It mainly covers audio and video compression artifacts and impairments due to packet loss. The quality tests conducted for model development demonstrate a mutual influence of the perceived audio and video quality, and the predominance of the video quality for the overall audiovisual quality. The balance between audio quality and video quality, however, depends on the content, the video format, and the audio degradation type. The proposed model is based on impairment factors which quantify the quality-impact of the different degradations. The impairment factors are computed from parameters extracted from the bitstream or packet headers. For high definition video, the model predictions show a correlation with unknown subjective ratings of 95%. For comparison, we have developed a more classical audiovisual quality model which is based on the audio and video qualities and their interaction. Both quality- and impairment-factor-based models are further refined by taking the content-type into account. At last, the different model variants are compared with modeling approaches described in the literature.

  8. An approach for quantitative image quality analysis for CT

    Science.gov (United States)

    Rahimi, Amir; Cochran, Joe; Mooney, Doug; Regensburger, Joe

    2016-03-01

    An objective and standardized approach to assess image quality of Compute Tomography (CT) systems is required in a wide variety of imaging processes to identify CT systems appropriate for a given application. We present an overview of the framework we have developed to help standardize and to objectively assess CT image quality for different models of CT scanners used for security applications. Within this framework, we have developed methods to quantitatively measure metrics that should correlate with feature identification, detection accuracy and precision, and image registration capabilities of CT machines and to identify strengths and weaknesses in different CT imaging technologies in transportation security. To that end we have designed, developed and constructed phantoms that allow for systematic and repeatable measurements of roughly 88 image quality metrics, representing modulation transfer function, noise equivalent quanta, noise power spectra, slice sensitivity profiles, streak artifacts, CT number uniformity, CT number consistency, object length accuracy, CT number path length consistency, and object registration. Furthermore, we have developed a sophisticated MATLAB based image analysis tool kit to analyze CT generated images of phantoms and report these metrics in a format that is standardized across the considered models of CT scanners, allowing for comparative image quality analysis within a CT model or between different CT models. In addition, we have developed a modified sparse principal component analysis (SPCA) method to generate a modified set of PCA components as compared to the standard principal component analysis (PCA) with sparse loadings in conjunction with Hotelling T2 statistical analysis method to compare, qualify, and detect faults in the tested systems.

  9. THE ACADEMIC PERSONNEL MOTIVATION - A FACTOR FOR HIGH QUALITY EDUCATIONAL PRODUCT

    Directory of Open Access Journals (Sweden)

    Viara Slavianska

    2014-06-01

    Full Text Available The present paper consecutively puts an accent on 1 the quality of higher education as a national priority, 2 the qualification and motivation of the academic staff as factors for offering an educational product of high quality, 3 the strategies, policies and practices for motivating the academic personnel. The necessity of education improvement is adduced, the strategies and politics in the field of academic personnel training are presented, and the possible effects from a wrong approach to employees’ motivation in academic environment are commented.

  10. Society demands for the quality of education as a factor of modern education space forming

    Directory of Open Access Journals (Sweden)

    Ivanova Svetlana V.

    2016-01-01

    Full Text Available The authors research the problems of increasing in modern conditions society demands for qualitative characteristics of education services. The quality of education is considered as one of the determining factors of forming educational space. The paper analyzes the influence of social and economic conditions inherent in the post-industrial era on forming and transforming of education space at the modern stage of society development, shows the ways to overcome emerging contradictions. The authors pay special attention to the significance of project approach in solving the problems of improving education quality.

  11. Occupants' satisfaction toward building environmental quality: structural equation modeling approach.

    Science.gov (United States)

    Kamaruzzaman, Syahrul Nizam; Egbu, C O; Zawawi, Emma Marinie Ahmad; Karim, Saipol Bari Abd; Woon, Chen Jia

    2015-05-01

    It is accepted that occupants who are more satisfied with their workplace's building internal environment are more productive. The main objective of the study was to measure the occupants' level of satisfaction and the perceived importance of the design or refurbishment on office conditions. The study also attempted to determine the factors affecting the occupants' satisfaction with their building or office conditions. Post-occupancy evaluations were conducted using a structured questionnaire developed by the Built Environment Research Group at the University of Manchester, UK. Our questionnaires incorporate 22 factors relating to the internal environment and rate these in terms of "user satisfaction" and "degree of importance." The questions were modified to reflect the specific setting of the study and take into consideration the local conditions and climate in Malaysia. The overall mean satisfaction of the occupants toward their office environment was 5.35. The results were measured by a single item of overall liking of office conditions in general. Occupants were more satisfied with their state of health in the workplace, but they were extremely dissatisfied with the distance away from a window. The factor analysis divided the variables into three groups, namely intrusion, air quality, and office appearance. Structural equation modeling (SEM) was then used to determine which factor had the most significant influence on occupants' satisfaction: appearance. The findings from the study suggest that continuous improvement in aspects of the building's appearance needs to be supported with effective and comprehensive maintenance to sustain the occupants' satisfaction.

  12. Fuzzy set approach to quality function deployment: An investigation

    Science.gov (United States)

    Masud, Abu S. M.

    1992-01-01

    The final report of the 1992 NASA/ASEE Summer Faculty Fellowship at the Space Exploration Initiative Office (SEIO) in Langley Research Center is presented. Quality Function Deployment (QFD) is a process, focused on facilitating the integration of the customer's voice in the design and development of a product or service. Various input, in the form of judgements and evaluations, are required during the QFD analyses. All the input variables in these analyses are treated as numeric variables. The purpose of the research was to investigate how QFD analyses can be performed when some or all of the input variables are treated as linguistic variables with values expressed as fuzzy numbers. The reason for this consideration is that human judgement, perception, and cognition are often ambiguous and are better represented as fuzzy numbers. Two approaches for using fuzzy sets in QFD have been proposed. In both cases, all the input variables are considered as linguistic variables with values indicated as linguistic expressions. These expressions are then converted to fuzzy numbers. The difference between the two approaches is due to how the QFD computations are performed with these fuzzy numbers. In Approach 1, the fuzzy numbers are first converted to their equivalent crisp scores and then the QFD computations are performed using these crisp scores. As a result, the output of this approach are crisp numbers, similar to those in traditional QFD. In Approach 2, all the QFD computations are performed with the fuzzy numbers and the output are fuzzy numbers also. Both the approaches have been explained with the help of illustrative examples of QFD application. Approach 2 has also been applied in a QFD application exercise in SEIO, involving a 'mini moon rover' design. The mini moon rover is a proposed tele-operated vehicle that will traverse and perform various tasks, including autonomous operations, on the moon surface. The output of the moon rover application exercise is a

  13. Light-cone sum rule approach for Baryon form factors

    CERN Document Server

    Offen, Nils

    2016-01-01

    We present the state-of-the-art of the light-cone sum rule approach to Baryon form factors. The essence of this approach is that soft Feynman contributions are calculated in terms of small transverse distance quantities using dispersion relations and duality. The form factors are thus expressed in terms of nucleon wave functions at small transverse separations, called distribution amplitudes, without any additional parameters. The distribution amplitudes, therefore, can be extracted from the comparison with the experimental data on form factors and compared to the results of lattice QCD simulations.

  14. Light-Cone Sum Rule Approach for Baryon Form Factors

    Science.gov (United States)

    Offen, Nils

    2016-10-01

    We present the state-of-the-art of the light-cone sum rule approach to Baryon form factors. The essence of this approach is that soft Feynman contributions are calculated in terms of small transverse distance quantities using dispersion relations and duality. The form factors are thus expressed in terms of nucleon wave functions at small transverse separations, called distribution amplitudes, without any additional parameters. The distribution amplitudes, therefore, can be extracted from the comparison with the experimental data on form factors and compared to the results of lattice QCD simulations.

  15. Adaptation of a 3-factor model for the Pittsburgh Sleep Quality Index in Portuguese older adults.

    Science.gov (United States)

    Becker, Nathália Brandolim; de Neves Jesus, Saul

    2017-05-01

    The present study examined the factor structure of the Pittsburgh Sleep Quality Index (PSQI) in a sample of older Portuguese adults using a cross-validation approach. Design is a cross-sectional. A convenience sample of 204 community-dwelling older adults (M=70.05, SD=7.15) were included. The global sleep quality (GSQ) score ranged from 0 to 18 with a mean of 5.98 (SD±3.45). The distribution showed that gender and perception of oneself as healthy influences GSQ in this sample. Cronbach's α was 0.69, but increased to 0.70 if the "use of sleep medication" component was deleted. Exploratory factor analysis (EFA) demonstrated two factor model is better than one factor, and a model fit with good indices (chi-square=8.649, df=8, p=0.373). Confirmatory factor analysis (CFA) was performed on the single factor, two factor, and three factor models, with and without the "use of sleep medications" component. The best model was the 3-factor model without the "use of sleep medications" component (chi-square=1.214, df=6, GFI=0.997, AGFI=0.918, CFI=0.986, RMSEA=0.046). The adaptation of the model is similar to the original model, with the only change being the exclusion of the "use of medications to sleep" component. We suggest using that component as a complementary qualitative assessment of health. Copyright © 2017 Elsevier Ireland Ltd. All rights reserved.

  16. Methodical approaches to assessment of quality of the bank loan portfolio

    Directory of Open Access Journals (Sweden)

    Tysyachna Yunna S.

    2014-01-01

    Full Text Available The goal of the article lies in the study of basic methodical approaches to assessment of the quality of the bank loan portfolio, identification of specific features of their practical application and justification of selection of the most appropriate for the modern economic conditions. The article considers three main groups of methods of assessment of the quality of the bank loan portfolio: expert evaluation methods and statistical and analytical methods. It goes without saying that in order to obtain an objective assessment of quality of the bank loan portfolio it is necessary to apply a complex approach, however, due to some advantages and shortcomings of the studied methods, the author marks expediency of building an integral indicator, taxonomic in particular, in order to obtain a complex, objective and efficient assessment of the bank loan portfolio. Prospects of further studies in this direction are assessment of the quality of the loan portfolio of the first group banks by the size of their assets through building integral taxonomic indicators and identification, on this basis, of factors that influence the quality of the loan portfolio with the aim of improvement of the mechanism of management of the bank lending activity.

  17. PARETO ANALYSIS OF TOTAL QUALITY MANAGEMENT FACTORS CRITICAL TO SUCCESS FOR SERVICE INDUSTRIES

    Directory of Open Access Journals (Sweden)

    Faisal Talib

    2010-06-01

    Full Text Available Total quality management (TQM is an integrated management approach that aim to continuously improve the performance of products, processes, and services to achieve and surpass customer's expectations. To accomplish this objective, some key factors that contribute to the success of TQM efforts are to be identified. These key factors are often termed as critical success factors (CSFs. The purpose of the present study is to identify and propose a list of "vital few" TQM CSFs for the benefit of researchers and service industries practitioners. A quality tool "Pareto analysis" was used to sort and arrange the CSFs according to the order of criticality. A few vital CSFs were identified and reported. The results of this study will help in successful implementation of TQM program in organizations. The managerial implications, research recommendations, and scope for future research work are presented in the end.

  18. The geographical factor in the determination of audit quality

    Directory of Open Access Journals (Sweden)

    Antonio Luis Duréndez Gómez-Guillamón

    2012-12-01

    Full Text Available The aim of this research paper is to analyze the role of the spatial factor in the determination of audit quality. Concretely, we hypothesize that audit quality is influenced by location and by the existence of spill-over effects generated by two factors: (1 the specialization and reputation of auditing firms and (2 the economic and institutional development of the audit firm’s location. We developed an empirical research to test the existence of such spatial effects (location and spill-over on a representative sample of the Spanish audit market. The study includes spatial econometric techniques taking into account the auditee specific characteristics, as well as other external factors. The findings highlight the relevance of including the spatial dimension when the audit quality is being studied. The results confirm the existence of a location effect according to the highest quality values are found in the most developed Spanish areas. Furthermore, we find a spatial spill-over effect among regions, affecting audit quality values. This effect confirms that audit quality within a location spreads to its surroundings. The results support the promotion of governmental policies leading to improve audit quality considering the spill-over effect.KEYWORDS: RESUMENEl objetivo de este artículo es analizar la influencia del factor geográfico en la determinación de la calidad de la auditoría. En concreto, la hipótesis que se plantea sostiene que la calidad de la auditoría se ve afectada por la ubicación y por la existencia de efectos indirectos generados por dos factores: (1 la especialización y la reputación de las firmas de auditoría y (2 el desarrollo económico e institucional de la provincia donde se localiza la firma de auditoría. Con este objetivo hemos desarrollado un estudio empírico para probar la existencia de tales efectos espaciales (ubicación y desbordamiento en una muestra representativa del mercado de auditoría español. El

  19. Quality-of-life factors in adolescent inflammatory bowel disease.

    Science.gov (United States)

    MacPhee, M; Hoffenberg, E J; Feranchak, A

    1998-02-01

    Little is known about the specific psychosocial factors that influence quality of life in adolescents with newly diagnosed inflammatory bowel disease (IBD). We adapted a model by Garrett and Drossman to assess adolescent adjustment to recent-onset IBD. Thirty adolescent-parent pairs completed a set of standardized questionnaires. The inclusion criteria were adolescents 12-18 years of age with Crohn's disease or ulcerative colitis of life scores significantly correlated with satisfaction and degree of closeness with their social support members, such as parents. An unexpected finding was that the adolescents included more extended family than peers in their social support networks. Also of note was that parental coping styles rather than adolescent coping styles significantly correlated with adolescents' quality-of-life health scores. Severity of illness did not correlate with adolescent quality-of-life health scores. There was significant agreement between adolescent and parental quality-of-life health scores and stressful event ratings. Adolescents with recent-onset IBD rely more on family members than their peers for emotional support, and they depend more on their parents' coping skills than their own. These findings may indicate lags in normal adolescent development. Adolescents and parents do communicate and share concerns with each other. Support programs for adolescents with IBD should reinforce existing coping skills and parent-adolescent communication while promoting normative development.

  20. Quality by design approach for understanding the critical quality attributes of cyclosporine ophthalmic emulsion.

    Science.gov (United States)

    Rahman, Ziyaur; Xu, Xiaoming; Katragadda, Usha; Krishnaiah, Yellela S R; Yu, Lawrence; Khan, Mansoor A

    2014-03-03

    Restasis is an ophthalmic cyclosporine emulsion used for the treatment of dry eye syndrome. There are no generic products for this product, probably because of the limitations on establishing in vivo bioequivalence methods and lack of alternative in vitro bioequivalence testing methods. The present investigation was carried out to understand and identify the appropriate in vitro methods that can discriminate the effect of formulation and process variables on critical quality attributes (CQA) of cyclosporine microemulsion formulations having the same qualitative (Q1) and quantitative (Q2) composition as that of Restasis. Quality by design (QbD) approach was used to understand the effect of formulation and process variables on critical quality attributes (CQA) of cyclosporine microemulsion. The formulation variables chosen were mixing order method, phase volume ratio, and pH adjustment method, while the process variables were temperature of primary and raw emulsion formation, microfluidizer pressure, and number of pressure cycles. The responses selected were particle size, turbidity, zeta potential, viscosity, osmolality, surface tension, contact angle, pH, and drug diffusion. The selected independent variables showed statistically significant (p quality control or sameness of cyclosporine ophthalmic products.

  1. Innovative biological approaches for monitoring and improving water quality

    Directory of Open Access Journals (Sweden)

    Sanja eAracic

    2015-08-01

    Full Text Available Water quality is largely influenced by the abundance and diversity of indigenous microbes present within an aquatic environment. Physical, chemical and biological contaminants from anthropogenic activities can accumulate in aquatic systems causing detrimental ecological consequences. Approaches exploiting microbial processes are now being utilized for the detection, and removal or reduction of contaminants. Contaminants can be identified and quantified in situ using microbial whole-cell biosensors, negating the need for water samples to be tested off-site. Similarly, the innate biodegradative processes can be enhanced through manipulation of the composition and/or function of the indigenous microbial communities present within the contaminated environments. Biological contaminants, such as detrimental/pathogenic bacteria, can be specifically targeted and reduced in number using bacteriophages. This mini-review discusses the potential application of whole-cell microbial biosensors for the detection of contaminants, the exploitation of microbial biodegradative processes for environmental restoration and the manipulation of microbial communities using phages.

  2. AMAZON RAINFOREST COSMETICS: CHEMICAL APPROACH FOR QUALITY CONTROL

    Directory of Open Access Journals (Sweden)

    Mariko Funasaki

    2016-02-01

    Full Text Available The market for natural cosmetics featuring ingredients derived from Amazon natural resources is growing worldwide. However, there is neither enough scientific basis nor quality control of these ingredients. This paper is an account of the chemical constituents and their biological activities of fourteen Amazonian species used in cosmetic industry, including açaí (Euterpe oleracea, andiroba (Carapa guianensis, bacuri (Platonia insignis, Brazil nut (Bertholletia excelsa, buriti (Mauritia vinifera or M. flexuosa, cumaru (Dipteryx odorata, cupuaçu (Theobroma grandiflorum, guarana (Paullinia cupana, mulateiro (Calycophyllum spruceanum, murumuru (Astrocaryum murumuru, patawa (Oenocarpus bataua or Jessenia bataua, pracaxi (Pentaclethra macroloba, rosewood (Aniba rosaeodora, and ucuuba (Virola sebifera. Based on the reviewed articles, we selected chemical markers for the quality control purpose and evaluated analytical methods. Even though chromatographic and spectroscopic methods are major analytical techniques in the studies of these species, molecular approaches will also be important as used in food and medicine traceability. Only a little phytochemical study is available about most of the Amazonian species and some species such as açaí and andiroba have many reports on chemical constituents, but studies on biological activities of isolated compounds and sampling with geographical variation are limited.

  3. A Signal Detection Theory Approach to Evaluating Oculometer Data Quality

    Science.gov (United States)

    Latorella, Kara; Lynn, William, III; Barry, John S.; Kelly, Lon; Shih, Ming-Yun

    2013-01-01

    Currently, data quality is described in terms of spatial and temporal accuracy and precision [Holmqvist et al. in press]. While this approach provides precise errors in pixels, or visual angle, often experiments are more concerned with whether subjects'points of gaze can be said to be reliable with respect to experimentally-relevant areas of interest. This paper proposes a method to characterize oculometer data quality using Signal Detection Theory (SDT) [Marcum 1947]. SDT classification results in four cases: Hit (correct report of a signal), Miss (failure to report a ), False Alarm (a signal falsely reported), Correct Reject (absence of a signal correctly reported). A technique is proposed where subjects' are directed to look at points in and outside of an AOI, and the resulting Points of Gaze (POG) are classified as Hits (points known to be internal to an AOI are classified as such), Misses (AOI points are not indicated as such), False Alarms (points external to AOIs are indicated as in the AOI), or Correct Rejects (points external to the AOI are indicated as such). SDT metrics describe performance in terms of discriminability, sensitivity, and specificity. This paper presentation will provide the procedure for conducting this assessment and an example of data collected for AOIs in a simulated flightdeck environment.

  4. Health related quality of life and influencing factors among welders.

    Directory of Open Access Journals (Sweden)

    Jingxiang Qin

    Full Text Available BACKGROUND: Occupational exposure to welding fumes is a serious occupational health problem all over the world. Welders are exposed to many occupational hazards; these hazards might cause some occupational diseases. The aim of the study was to assess the health related quality of life (HRQL of electric welders in Shanghai China and explore influencing factors to HRQL of welders. METHODS: 301 male welders (without pneumoconiosis and 305 non-dust male workers in Shanghai were enrolled in this study. Short Form-36 (SF-36 health survey questionnaires were applied in this cross-sectional study. Socio-demographic, working and health factors were also collected. Multiple stepwise regress analysis was used to identify significant factors related to the eight dimension scores. RESULTS: Six dimensions including role-physical (RP, bodily pain (BP, general health (GH, validity (VT, social function (SF, and mental health (MH were significantly worse in welders compared to non-dust workers. Multiple stepwise regress analysis results show that native place, monthly income, quantity of children, drinking, sleep time, welding type, use of personal protective equipment (PPE, great events in life, and some symptoms including dizziness, discomfort of cervical vertebra, low back pain, cough and insomnia may be influencing factors for HRQL of welders. Among these factors, only sleep time and the use of PPE were salutary. CONCLUSIONS: Some dimensions of HRQL of these welders have been affected. Enterprises which employ welders should take measures to protect the health of these people and improve their HRQL.

  5. Open Economy, Institutional Quality, and Environmental Performance: A Macroeconomic Approach

    Directory of Open Access Journals (Sweden)

    Amaryllis Mavragani

    2016-06-01

    Full Text Available As the subject of how economic development affects the quality of the natural environment has gained great momentum, this paper focuses on examining the extent to which the openness of a market economy and the quality of the institution affect environmental performance. The majority of the current studies focus on the Environmental Kuznets Curve and the level of economic growth. This paper addresses this question by relating environmental (“Environmental Performance Index” to macroeconomic (Gross Domestic Product per capita, “Open Markets Index” and governance indicators (“Worldwide Governance Indicators”. The sample consists of 75 countries, including all G20 and EU members, comprising “more than 90% of global trade and investment”. Findings show that the Environmental Performance Index is positively correlated to each of the (institutional indicators, so as to confirm that the selected indices are consistent with previous studies, suggesting that environmental performance increases in line with economic development and that good governance increases a country’s levels of environmental protection. By applying factor analysis, an empirical model of the Environmental Performance Index is estimated, suggesting that there is a significant positive correlation between a country’s economic growth, the openness of an economy, high levels of effective governance, and its environmental performance.

  6. Does Satisfaction with Teaching Quality Factors Bring Conceptual Change?

    Directory of Open Access Journals (Sweden)

    Saifur Rehman Khan

    2014-05-01

    Full Text Available The purpose of this study is to explore classroom teaching quality factors that determine the satisfaction level and ultimately bring conceptual change among students. This study tests the theories of customer satisfaction in educational psychology research on a sample of 972 respondents. Overwhelmingly the results point out that male students were highly dissatisfied and have little impact on conceptual change whereas female students were reported significant level of satisfaction and conceptual change. In conclusion, detailed empirical analyses promote the theory of learning-satisfaction with classroom teaching bring conceptual change.

  7. Analytical quality-by-design approach for sample treatment of BSA-containing solutions

    Institute of Scientific and Technical Information of China (English)

    Lien Taevernier; Evelien Wynendaele; Matthias D’Hondt; Bart De Spiegeleer

    2015-01-01

    The sample preparation of samples containing bovine serum albumin (BSA), e.g., as used in transdermal Franz diffusion cell (FDC) solutions, was evaluated using an analytical quality-by-design (QbD) approach. Traditional precipitation of BSA by adding an equal volume of organic solvent, often successfully used with conventional HPLC-PDA, was found insufficiently robust when novel fused-core HPLC and/or UPLC-MS methods were used. In this study, three factors (acetonitrile (%), formic acid (%) and boiling time (min)) were included in the experimental design to determine an optimal and more suitable sample treatment of BSA-containing FDC solutions. Using a QbD and Derringer desirability (D) approach, combining BSA loss, dilution factor and variability, we constructed an optimal working space with the edge of failure defined as Do0.9. The design space is modelled and is confirmed to have an ACN range of 8373%and FA content of 170.25%.

  8. Systems approach to managing educational quality in the engineering classroom

    Science.gov (United States)

    Grygoryev, Kostyantyn

    Today's competitive environment in post-secondary education requires universities to demonstrate the quality of their programs in order to attract financing, and student and academic talent. Despite significant efforts devoted to improving the quality of higher education, systematic, continuous performance measurement and management still have not reached the level where educational outputs and outcomes are actually produced---the classroom. An engineering classroom is a complex environment in which educational inputs are transformed by educational processes into educational outputs and outcomes. By treating a classroom as a system, one can apply tools such as Structural Equation Modeling, Statistical Process Control, and System Dynamics in order to discover cause-and-effect relationships among the classroom variables, control the classroom processes, and evaluate the effect of changes to the course organization, content, and delivery, on educational processes and outcomes. Quality improvement is best achieved through the continuous, systematic application of efforts and resources. Improving classroom processes and outcomes is an iterative process that starts with identifying opportunities for improvement, designing the action plan, implementing the changes, and evaluating their effects. Once the desired objectives are achieved, the quality improvement cycle may start again. The goal of this research was to improve the educational processes and outcomes in an undergraduate engineering management course taught at the University of Alberta. The author was involved with the course, first, as a teaching assistant, and, then, as a primary instructor. The data collected from the course over four years were used to create, first, a static and, then, a dynamic model of a classroom system. By using model output and qualitative feedback from students, changes to the course organization and content were introduced. These changes led to a lower perceived course workload and

  9. Quality by Design approach for studying the impact of formulation and process variables on product quality of oral disintegrating films.

    Science.gov (United States)

    Mazumder, Sonal; Pavurala, Naresh; Manda, Prashanth; Xu, Xiaoming; Cruz, Celia N; Krishnaiah, Yellela S R

    2017-07-15

    The present investigation was carried out to understand the impact of formulation and process variables on the quality of oral disintegrating films (ODF) using Quality by Design (QbD) approach. Lamotrigine (LMT) was used as a model drug. Formulation variable was plasticizer to film former ratio and process variables were drying temperature, air flow rate in the drying chamber, drying time and wet coat thickness of the film. A Definitive Screening Design of Experiments (DoE) was used to identify and classify the critical formulation and process variables impacting critical quality attributes (CQA). A total of 14 laboratory-scale DoE formulations were prepared and evaluated for mechanical properties (%elongation at break, yield stress, Young's modulus, folding endurance) and other CQA (dry thickness, disintegration time, dissolution rate, moisture content, moisture uptake, drug assay and drug content uniformity). The main factors affecting mechanical properties were plasticizer to film former ratio and drying temperature. Dissolution rate was found to be sensitive to air flow rate during drying and plasticizer to film former ratio. Data were analyzed for elucidating interactions between different variables, rank ordering the critical materials attributes (CMA) and critical process parameters (CPP), and for providing a predictive model for the process. Results suggested that plasticizer to film former ratio and process controls on drying are critical to manufacture LMT ODF with the desired CQA. Published by Elsevier B.V.

  10. Humanistic Approach and Affective Factors in Foreign Language Teaching

    Institute of Scientific and Technical Information of China (English)

    罗馨

    2010-01-01

    For a long time,Chinese EFL teaching has been following the teacher-centered model,which emphasizes the cognitive aspect but ignores the affective factors. So "emotional illiteracy" is a common phemenon and harmful to language learning and students' all-round development. This essay lays special stress on humanistic approach and analyzes the influence of some important affective factors on language learning,for the purpose of inviting teachers' attention to students' emotions in fulfilling their teaching task.

  11. Factorization approach to superintegrable systems: Formalism and applications

    Science.gov (United States)

    Ballesteros, Á.; Herranz, F. J.; Kuru, Ş.; Negro, J.

    2017-03-01

    The factorization technique for superintegrable Hamiltonian systems is revisited and applied in order to obtain additional (higher-order) constants of the motion. In particular, the factorization approach to the classical anisotropic oscillator on the Euclidean plane is reviewed, and new classical (super) integrable anisotropic oscillators on the sphere are constructed. The Tremblay-Turbiner-Winternitz system on the Euclidean plane is also studied from this viewpoint.

  12. Factorization approach to superintegrable systems: Formalism and applications

    Energy Technology Data Exchange (ETDEWEB)

    Ballesteros, Á., E-mail: angelb@ubu.es; Herranz, F. J., E-mail: fjherranz@ubu.es [Universidad de Burgos, Departamento de Física (Spain); Kuru, Ş., E-mail: kuru@science.ankara.edu.tr [Ankara University, Department of Physics, Faculty of Science (Turkey); Negro, J., E-mail: jnegro@fta.uva.es [Universidad de Valladolid, Departamento de Física Teórica, Atómica y Óptica (Spain)

    2017-03-15

    The factorization technique for superintegrable Hamiltonian systems is revisited and applied in order to obtain additional (higher-order) constants of the motion. In particular, the factorization approach to the classical anisotropic oscillator on the Euclidean plane is reviewed, and new classical (super) integrable anisotropic oscillators on the sphere are constructed. The Tremblay–Turbiner–Winternitz system on the Euclidean plane is also studied from this viewpoint.

  13. Coastal water quality estimation from Geostationary Ocean Color Imager (GOCI) satellite data using machine learning approaches

    Science.gov (United States)

    Im, Jungho; Ha, Sunghyun; Kim, Yong Hoon; Ha, Hokyung; Choi, Jongkuk; Kim, Miae

    2014-05-01

    It is important to monitor coastal water quality using key parameters such as chlorophyll-a concentration and suspended sediment to better manage coastal areas as well as to better understand the nature of biophysical processes in coastal seawater. Remote sensing technology has been commonly used to monitor coastal water quality due to its ability of covering vast areas at high temporal resolution. While it is relatively straightforward to estimate water quality in open ocean (i.e., Case I water) using remote sensing, coastal water quality estimation is still challenging as many factors can influence water quality, including various materials coming from inland water systems and tidal circulation. There are continued efforts to accurately estimate water quality parameters in coastal seawater from remote sensing data in a timely manner. In this study, two major water quality indicators, chlorophyll-a concentration and the amount of suspended sediment, were estimated using Geostationary Ocean Color Imager (GOCI) satellite data. GOCI, launched in June 2010, is the first geostationary ocean color observation satellite in the world. GOCI collects data hourly for 8 hours a day at 6 visible and 2 near-infrared bands at a 500 m resolution with 2,500 x 2,500 km square around Korean peninsula. Along with conventional statistical methods (i.e., various linear and non-linear regression), three machine learning approaches such as random forest, Cubist, and support vector regression were evaluated for coastal water quality estimation. In situ measurements (63 samples; including location, two water quality parameters, and the spectra of surface water using a hand-held spectroradiometer) collected during four days between 2011 and 2012 were used as reference data. Due to the small sample size, leave-one-out cross validation was used to assess the performance of the water quality estimation models. Atmospherically corrected radiance data and selected band-ratioed images were used

  14. Identification af explosive power factors as predictors of player quality in young female volleyball players.

    Science.gov (United States)

    Grgantov, Zoran; Milić, Mirjana; Katić, Ratko

    2013-05-01

    With the purpose of determining the factor structure of explosive power, as well as the influence of each factor on situational efficiency, 56 young female volleyball players were tested using 14 tests for assessing nonspecific and specific explosive power. By factor analysis, 4 significant factors were isolated which explained the total of over 80% of the common variability in young female volleyball players. The first factor was defined as volleyball-specific jumping, the second factor as nonspecific jumping and sprinting, the third factor as throwing explosive power, while the fourth factor was interpreted as volleyball-specific throwing and spiking speed from the ground. Results obtained by regression analysis in the latent space of explosive power indicate that the identified factors are good predictors of player quality in young female volleyball players. The fourth factor defined as throwing and spiking speed from the ground had the largest influence on player quality, followed by volleyball-specific jumping and nonspecific jumping and sprinting, and to a much lesser extent, by throwing explosive power The results obtained in this age group bring to the fore the ability of spiking and serving a ball of high speed, which hinders the opponents from playing those balls in serve reception and field defence. This ability, combined with a high standing vertical jump reach and spike approach vertical jump reach (which is the basis of the 1st varimax factor) enables successful performance of all volleyball elements by which points are won in complex 1 (spike) and complex 2 (serve and block). Even though the 2nd factor (nonspecific jumping and sprinting) has a slightly smaller impact on situational efficiency in young players, this ability provides preconditions i.e. preparation for successful realisation of all volleyball elements, so greater attention must be paid to perfecting it in young female volleyball players.

  15. The Idea of Quality in Higher Education: A Conceptual Approach

    Science.gov (United States)

    Filippakou, Ourania

    2011-01-01

    The paper suggests that the idea of quality in higher education is ideologically constructed and conducted. In a spiral of mutual reinforcements, quality regimes naturalise experience, while the theories of that practice legitimise the naturalness of "quality". I shall suggest that quality regimes provide too narrow readings of higher education.…

  16. Professional quality of life and associated factors among VHA chaplains.

    Science.gov (United States)

    Yan, Grace W; Beder, Joan

    2013-06-01

    Chaplains play a unique role in the Veterans Affairs (VA) health care systems and have numerous responsibilities. Compassion satisfaction (CS), compassion fatigue (CF), and burnout (BO) are three major phenomenons that have been documented in other helping professions, but little is known about VA Chaplains' professional quality of life. This study examines a national sample of VA Chaplains and their professional quality of life along with associated factors. Two-hundred and seventeen VA Chaplains completed an anonymous Internet survey, and regression analyses were conducted to determine which variables affect professional quality of life. On average, participants report high levels of CS and low levels of CF and BO. Gender, perceived support from VA administration, and mental health (MH) integration were significant predictors for CS. MH integration and perceived support significantly affected CF. Age, MH integration, and perceived support affected BO. Significant interaction effects were found for CF and BO. In summary, younger Chaplains and Chaplains who report low levels of collaboration with MH professionals are most likely to develop CF and BO. This supports continued support from the VA for interdisciplinary initiatives and mentorship of younger Chaplains.

  17. The Quality Factor of the Folded Cylindrical Helix

    Directory of Open Access Journals (Sweden)

    S. R. Best

    2009-12-01

    Full Text Available Any electrically small antenna can be impedance matched at any single frequency using a number of well known techniques. Once the small antenna is impedance matched, the primary characteristics of interest are its radiation efficiency, its operating bandwidth and to a lesser extent, its radiation patterns. The bandwidth of the small antenna is often quantified using the antenna's quality factor (Q since fundamental lower bounds for Q are defined in terms of the antenna's occupied volume. The lower bound on Q, also known as the Chu-limit, is defined in terms of the spherical volume occupied by the antenna. However, many small antenna designs are constrained to fit within volumes other than a sphere. To address this issue, Gustafsson et al derived lower bounds for antennas of arbitrary shape with a specific focus on cylindrical and planar shaped antennas. In this paper we consider the quality factor of the folded cylindrical helix, an antenna design that effectively utilizes the available cylindrical volume. We compare its Q to the Gustaffson limit as a function of length-to-diameter ratio, while maintaining a fixed value of ka, and show that it’s Q is at or above Gustafsson’s lower bound for cylindrical shaped antennas.

  18. A NEW APPROACH TO MANAGING APPLICATION DEVELOPMENT FROM ASPECTS OF QUALITY

    Directory of Open Access Journals (Sweden)

    Zora Arsovski

    2007-09-01

    Full Text Available Objectives and methodologies for application development are derived from the business goals and financial factors, and many include productivity, flexibility and quality goals. According to V-diagram, next steps are identification and modeling for business process, business entities and design of ICT (Information and Communication Technology infrastructure. Many of these elements completely or partly already exist in organizations. They depict existing knowledge and usage of methods in organizations, which should be performed in order to achieve effective and efficient managing application development. Long experience of authors in design on information systems and quality systems points that large overlapping exists between these development methodologies. It was the main reason that motivated authors to develop a new approach of integrated development of information systems, mainly application development, and quality management systems (QMS. This approach is tested in several organizations in the field of production. In this paper we presented a basic of a new approach for application development based on processes and QMS. Several characteristic solutions of process model and data model are presented.

  19. Pelleting of feed for broiler chickens: Factors affecting pellet quality

    Directory of Open Access Journals (Sweden)

    Daniel José Antoniol Miranda

    2011-01-01

    Full Text Available The efficiency of the pellet can be translated by the quality of the pellet which is defined as the proportion of intact pellets that come to feeders for chickens, i.e., its resistance to breakage between the feed mill and farms. The use of diets with a higher percentage of intact pellets results in better performance of birds when compared with the feed rations. The main factors that affect pellet quality are: characteristics of pelleting, the feed composition, particle size, pelleting temperature, moisture and steam injection. From a nutritional standpoint, one can consider that the smaller the particle size of food increased their contact with the digestive juices, which aids digestion and absorption of nutrients. However, finely ground lead to less stimulation and growth of intestinal ephitellium. But from the standpoint of production of feed, the larger the particle size of ingredients largest economy with energy and greater efficiency (tons / hour milling. Because of this, it is suggested that the particle sizes used vary between 500 and 700 ìm to not to cause loss of performance of the birds, nor the income from the factory. Increased energy, through the addition of oils and fats, have much influence on performance parameters of broilers and the quality of the pellet produced. The presence of oils and / or fat, depending on the amount, on its hydrophoby characteristic, causing damage to the particles aggregation acting as a lubricant between food particles and the matrix of pelleting, decreasing the pelleting pressure and its gelatinization, resulting into poor quality pellets.

  20. A quantitative approach to the traffic air quality problem: the Traffic Air Quality index.

    Science.gov (United States)

    Soliman, Ahmed S M; Jacko, Robert B

    2008-05-01

    The Traffic Air Quality (TAQ) model is a simple tool to estimate traffic fine particulate emissions on roadways (g/km) and can be used for both real-time analysis and for localized conformity analysis ("hot-spot" analysis for nonattainment areas) as defined by 40 CFR 93.123. This paper is a follow-up to a study published earlier regarding the development of the TAQ model. This paper shows how local air quality levels can be a factor in traffic management in nonattainment areas. Similar to the industrial source quotas measured in tons per year, it is proposed that road segments are to be assigned emission quotas (or TAQ indices) measured in pollutant mass emitted per road length (g/km) above which traffic-measures have to be taken to reduce the fine-particulates emissions on such road links. The TAQ model as well as traffic-rerouting measures along with the Intelligent Transportation System (ITS) protocols can be used to have a real-time control of the traffic conditions along expressways to maintain the fine-particulates emissions below the quota assigned per road link and consequently improving the over all local air quality in nonattainment areas.

  1. Improving the quality factor of microwave cavities for axion search experiments

    Science.gov (United States)

    Ahn, Saebyeok; Jung, Junu; Youn, Sungwoo; Semertzidis, Yannis

    2017-01-01

    In cavity-based axion search experiments, the quality factor (Q) of microwave resonant cavities is an important parameter to be sensitive to faint signal from the axion-to-photon conversion. One of the R&D efforts conducted at the Center for Axion and Precision Physics Research (CAPP) of the Institute for Basic Science (IBS) is to improve the quality factor of resonant cavities by employing two approaches - pure material and heat treatment. Using a 4K cryocooler and liquid helium, we measure the temperature dependence of Q value to find the effect of material purity and an optimal condition of heat treatment. The measurements are performed on Cu and Al cavities and the results are shown in this presentation.

  2. Liposomal Drug Products: A Quality by Design Approach

    Science.gov (United States)

    Xu, Xiaoming

    Quality by Design (QbD) principles has been applied to the development of two liposomal formulations, containing a hydrophilic small molecule therapeutic (Tenofovir) and a protein therapeutic (superoxide dismutase). The goal of the research is to provide critical information on 1) how to reduce the preparation variability in liposome formulations, and 2) how to increase drug encapsulation inside liposomes to reduce manufacturing cost. Most notably, an improved liposome preparation method was developed which increased the encapsulation efficiency of hydrophilic molecules. In particular, this method allows for very high encapsulation efficiency. For example, encapsulation efficiencies of up to 50% have been achieved, whereas previously only 20% or less have been reported. Another significant outcome from this research is a first principle mathematical model to predict the encapsulation efficiency of hydrophilic drugs in unilamellar liposomes. This mathematical model will be useful in: formulation development to rapidly achieve optimized formulations; comparison of drug encapsulation efficiencies of liposomes prepared using different methods; and assisting in the development of suitable process analytical technologies to achieve real-time monitoring and control of drug encapsulation during manufacturing. A novel two-stage reverse dialysis in vitro release testing method has also been developed for passively targeted liposomes, which uses the first stage to mimic the circulation of liposomes in the body and the second stage to imitate the drug release process at the target. The developed in vitro release testing method can be used to distinguish formulations with varied compositions for quality control testing purposes. This developed method may pave the way to the development of more biorelevant quality control testing methods for liposomal drug products in the future. The QbD case studies performed in this research are examples of how this approach can be used to

  3. Selective Prevention Approaches to Build Protective Factors in Early Intervention

    Science.gov (United States)

    Shapiro, Cheri J.

    2014-01-01

    Young children with disabilities may be at elevated risk for behavior problems as well as maltreatment. preventive approaches that can be infused into early intervention services are needed to support parents, build competencies among young children, and enhance protective factors that may temper risk. Two interventions--Stepping Stones Triple P,…

  4. Comparison of Different Numerical Methods for Quality Factor Calculation of Nano and Micro Photonic Cavities

    DEFF Research Database (Denmark)

    Taghizadeh, Alireza; Mørk, Jesper; Chung, Il-Sug

    2014-01-01

    Four different numerical methods for calculating the quality factor and resonance wavelength of a nano or micro photonic cavity are compared. Good agreement was found for a wide range of quality factors. Advantages and limitations of the different methods are discussed.......Four different numerical methods for calculating the quality factor and resonance wavelength of a nano or micro photonic cavity are compared. Good agreement was found for a wide range of quality factors. Advantages and limitations of the different methods are discussed....

  5. AN APPROACH TO THE QUALITY IMPROVEMENT OF A MASSIVE INVESTMENT PROJECT BY INTEGRATING ICT AND QMS

    Directory of Open Access Journals (Sweden)

    Tamara Gvozdenovic

    2007-12-01

    Full Text Available This work has presented an approach to the quality improvement of an investment project by the change in the concept of project management. Building time of the investment project is a complex factor which needs a special attention. It is well known that the PERT method has been applied with long-lasting investment projects, where a big time distance brings about significant uncertainty of future situations. Microsoft Project 2002 and Matlab: Neural Network Toolbox are the software tools used for solving the problem of investment project management.

  6. Analysis Approach to Durability Based on Material Initial Fatigue Quality and S-N Curve

    Institute of Scientific and Technical Information of China (English)

    Yang Moucun; Nie Hong

    2007-01-01

    Based on probabilistic fracture mechanics approach, a new concept of material initial fatigue quality (MIFQ) is developed. Then,the relation between S-N curve and crack propagation curve is studied. From the study, a new durability analysis method is presented. In this method, S-N curve is used to determine crack growth rate under constant amplitude.loading and evaluate the effects of different factors on durability and then the structural durability is analyzed. The tests and analyses indicate that this method has lower dependence on testing, and higher accuracy, reliability and generality and is convenient for application.

  7. Simulation-Based Fuzzy Logic Approach to Assessing the Effect of Project Quality Management on Construction Performance

    Directory of Open Access Journals (Sweden)

    Gilberto A. Corona-Suárez

    2014-01-01

    Full Text Available This paper reports the development of an approach to integrate the appropriate modeling techniques for estimating the effect of project quality management (PQM on construction performance. This modeling approach features a causal structure that depicts the interaction among the PQM factors affecting quality performance in a given construction operation. In addition, it makes use of fuzzy sets and fuzzy logic in order to incorporate the subjectivity and uncertainty implicit in the performance assessment of these PQM factors to discrete-event simulation models. The outcome is a simulation approach that allows experimenting with different performance levels of the PQM practices implemented in a construction project and obtaining the corresponding productivity estimates of the construction operations. These estimates are intended to facilitate the decision making regarding the improvement of a PQM system implemented in a construction project. A case study is used to demonstrate the usefulness of the proposed simulation approach for evaluating diverse performance improvement alternatives for a PQM system.

  8. Motivational factors as predictors of student approach to learning

    DEFF Research Database (Denmark)

    Lassesen, Berit

    for the remaining variables. Results: The results of the multiple linear regression showed that each of the motivational factors of self-efficacy, test-anxiety generally strong independent statistical significant predictors in the expected directions of students approach to learning, both when analyzed separately...... model: R2 = 0.279) and Surface approach (Final model: R2 = 0.214).Conclusion: Although successful learning largely depends on knowledge and skills, factors such as self efficacy and test anxiety play an important role as predictors of students’ learning approaches, and subsequent learning outcomes...... to obtaining them. Besides being a role model by showing enthusiasm for the subject, teachers are important moderators when it comes to building the ability and effort required for deep learning...

  9. A Cognitive Modeling Method of the Life Quality Indicators in Terms of External Factors

    Directory of Open Access Journals (Sweden)

    L. V. Massel

    2016-01-01

    Full Text Available The article discusses a potential use of the methods of cognitive modeling in the field of quality of life. The quality of life, as a universal indicator of human self-perception to feel his sense of satisfaction from various parts of his life, is difficult to assess by strictly mathematical methods, so the authors suggest using the cognitive modeling. The quality of life in his estimation for the convenience of research activity is divided into components - indicators of the quality of life. The widespread indicator "quality of life" and the complexity of the development of its assessment methods lead to high relevance of the authors-proposed method.The introduction provides an overview of current approaches to assessing the quality of life. Among all these approaches the most advantageous is an objectively subjective one. The paper gives a brief assessment of cognitive modeling methods, which are, essentially, a way of graphic and structural elements of reflection and relationships in complex systems. As a result of the analysis of existing research in this area, was found the potential for creating cognitive models of the quality of life and its indicators and was defined the place of the proposed method, among others. The paper presents the method itself, as a series of steps, and focuses on the promising opportunities for researchers of the quality of life from its using.Among the possible lines to use cognitive modeling of the life quality indicators can be three main ones: implementation of new methods to assess the quality of life; choice of the most appropriate technique for a particular study among available methods; realization of the cognitive model and numerical experiment, which allows seeing the effect of external factors on the individual indicators of the quality of life. Thus, due to the high relevance and significant benefits from the use of the proposed method, the article is of interest to researchers of the quality of life

  10. A quality metric for homology modeling: the H-factor

    Science.gov (United States)

    2011-01-01

    Background The analysis of protein structures provides fundamental insight into most biochemical functions and consequently into the cause and possible treatment of diseases. As the structures of most known proteins cannot be solved experimentally for technical or sometimes simply for time constraints, in silico protein structure prediction is expected to step in and generate a more complete picture of the protein structure universe. Molecular modeling of protein structures is a fast growing field and tremendous works have been done since the publication of the very first model. The growth of modeling techniques and more specifically of those that rely on the existing experimental knowledge of protein structures is intimately linked to the developments of high resolution, experimental techniques such as NMR, X-ray crystallography and electron microscopy. This strong connection between experimental and in silico methods is however not devoid of criticisms and concerns among modelers as well as among experimentalists. Results In this paper, we focus on homology-modeling and more specifically, we review how it is perceived by the structural biology community and what can be done to impress on the experimentalists that it can be a valuable resource to them. We review the common practices and provide a set of guidelines for building better models. For that purpose, we introduce the H-factor, a new indicator for assessing the quality of homology models, mimicking the R-factor in X-ray crystallography. The methods for computing the H-factor is fully described and validated on a series of test cases. Conclusions We have developed a web service for computing the H-factor for models of a protein structure. This service is freely accessible at http://koehllab.genomecenter.ucdavis.edu/toolkit/h-factor. PMID:21291572

  11. Examining the Factor Structure and Hierarchical Nature of the Quality of Life Construct

    Science.gov (United States)

    Wang, Mian; Schalock, Robert L.; Verdugo, Miguel A.; Jenaro, Christina

    2010-01-01

    There is considerable debate in the area of individual quality of life research regarding the factor structure and hierarchical nature of the quality of life construct. Our purpose in this study was to test via structural equation modeling an a priori quality of life model consisting of eight first-order factors and one second-order factor. Data…

  12. Interactions among Ecological Factors That Explain the Psychosocial Quality of Life of Children with Complex Needs

    Directory of Open Access Journals (Sweden)

    Sandy Thurston

    2010-01-01

    Full Text Available Purpose. To explore the associations and interactions among ecological factors and explain the psychosocial quality of life of children with complex needs. Methods. In this cross-sectional survey consenting parents were identified by the Children's Treatment Network. Families were eligible if the child from 0 to 19 years, resided in Simcoe/York, and there were multiple family needs. Regression analysis was used to explore associations and interactions. n=429. Results. Younger children, without conduct disorder, without hostile and punitive parenting and with low adverse family impact demonstrated the highest levels of psychosocial quality of life. Statistically significant interactions between processes of care and parent variables highlight the complexity of real life situations. Conclusions. It is not possible to fully understand the child's psychosocial quality of life in complex needs families by considering only simple associations between ecological factors. A multitude of factors and interactions between these factors are simultaneously present and the care of these families requires a holistic approach.

  13. Metabolomics: approaches to assessing oocyte and embryo quality.

    Science.gov (United States)

    Singh, R; Sinclair, K D

    2007-09-01

    Morphological evaluation remains the primary method of embryo assessment during IVF cycles, but its modest predictive power and inherent inter- and intra-observer variability limits its value. Low-molecular weight metabolites represent the end products of cell regulatory processes and therefore reveal the response of biological systems to a variety of genetic, nutrient or environmental influences. It follows that the non-invasive quantification of oocyte and embryo metabolism, from the analyses of follicular fluid or culture media, may be a useful predictor of pregnancy outcome following embryo transfer, a potential supported by recent clinical studies working with specific classes of metabolites such as glycolytic intermediates and amino acids. Such selective approaches, however, whilst adhering closely to known cellular processes, may fail to harness the full potential of contemporary metabolomic methodologies, which can measure a wider spectrum of metabolites. However, an important technical drawback with many existing methodologies is the limited number of metabolites that can be determined by a single analytical platform. Vibrational spectroscopy methodologies such as Fourier transform infrared and near infrared spectroscopy may overcome these limitations by generating unique spectral signatures of functional groups and bonds, but their application in embryo quality assessment remains to be fully validated. Ultimately, a combination of evaluation criteria that include morphometry with metabolomics may provide the best predictive assessment of embryo viability.

  14. A TOTAL QUALITY MANAGEMENT APPROACH TO CIVIL ENGINEERING CONSULTING

    Directory of Open Access Journals (Sweden)

    G.A.L. Ambrose

    2012-01-01

    Full Text Available

    ENGLISH ABSTRACT: The article describes the development of a framework for the implementation of a Total Quality Management (TQM approach in the civil consulting industry through the five phases of the typical civil engineering project. For any project to be successful the project team members must take collective and individual responsibility for their role in the project implementation. The organisational goal is “to make money now and in the future”. To achieve this goal the organization must provide value to its clientele. The clients are searching for the silver bullet; double the performance at half the price. TQM provides a means to achieve this goal.

    AFRIKAANSE OPSOMMING: Die artikel beskryf die ontwikkeling van 'n raamwerk vir die implementering van 'n gehaltebestuurstelsel vir die siviele raadgewende bedryf soos dit deelneem aan die vyf fases van 'n tipiese siviele ingenieursprojek. Vir die suksesvolle afhandeling van 'n projek is dit noodsaaklik dat alle projekspanlede gesamentlik en afsonderlik verantwoordelikheid moet aanvaar vir hulle eie betrokkenheid by die projekimplementering. Die organisasie se oogmerk is om “nou en in die toekoms geld te maak”. Ten einde hierdie oogmerk te bereik moet die organisasie waarde vir sy kliënte bied. 'n Gehaltebestuurstelsel voorsien die gereedskap om hierdie doelwit te bereik.

  15. QUALITY MANAGEMENT PRINCIPLES – AN APPROACH IN HEALTHCARE INSTITUTIONS

    OpenAIRE

    Kristina ZGODAVOVA; Sofia Elena COLESCA

    2007-01-01

    The problems of quality management systems development don´t seem to be interesting for healthcare institutions (HCI) at a glance. But a lot of managers and employees of HCI (including physicians) have already understood that their organizations also operate in environment, which asks for quality, performance and effectiveness. The quality management systems create a strategic framework in which every organization can meet these requirements. In case of HCI the term “quality management system...

  16. Factors associated with escalation and problematic approaches toward public figures.

    Science.gov (United States)

    Meloy, J Reid; James, David V; Mullen, Paul E; Pathé, Michele T; Farnham, Frank R; Preston, Lulu F; Darnley, Brian J

    2011-01-01

    Detailed comparison of factors associated with abnormal approach to the prominent and with escalation from communication to approach has not hitherto been undertaken. This partially reflects the failure of individual studies to adopt compatible terminologies. This study involves a careful dissection of six public figure studies, three involving U.S. politicians, two Hollywood celebrities, and one the British Royal Family. Common findings were unearthed across six headings. Approachers were significantly more likely to exhibit serious mental illness, engage in multiple means of communication, involve multiple contacts/targets, and to incorporate into their communication requests for help. They were significantly less likely to use threatening or antagonistic language in their communications, except in those cases involving security breaches. These results emphasize the importance of integrating mental health findings and preventive measures into risk management. Approach should not be regarded as a single behavioral category and has multiple motivations. Future studies should adopt standard terminology, preferably taken from the general stalking research.

  17. Psychopathology, quality of life, and related factors in children with celiac disease.

    Science.gov (United States)

    Sevinç, Eylem; Çetin, Fatih Hilmi; Coşkun, Banu Demet

    This study aimed to survey children with celiac disease (CD) for psychiatric disorders, determine the possible factors that predict psychopathology, and analyze health-related quality of life and possible factors that could affect the quality of life. In this study, all children completed the Schedule for Affective Disorders and Schizophrenia for School Age Children - Present and Lifetime Version - Turkish Version (K-SADS-PL-T), as well as the Pediatric Quality of Life Inventory (PedsQL) for the 8-12 age group, and a sentence completion test. A face-to-face interview was performed with the parents of the participants to inform them about the study. This study included 52 children with celiac disease in the age range of 8-12 years, and 40 healthy children. The mean age of the study group was 10.36±0.36 years, and 31 (59%) of them were females. The mean age of the control group was 10.35±0.46 years and 24 (60%) of them were females. The mean subscale scores of the Pediatric Quality of Life Inventory were significantly lower in children with celiac disease when compared to the control group (pceliac disease. This study has shown once more that celiac disease is associated with some psychiatric signs/diagnoses, and that it decreased quality of life. Further studies are needed to determine the factors that could reduce the psychiatric signs. It is apparent that those studies would contribute new approaches to improve diagnosis, treatment, and quality of life. Copyright © 2016 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. All rights reserved.

  18. Mie Plasmons: Modes Volumes, Quality Factors, and Coupling Strengths (Purcell Factor to a Dipolar Emitter

    Directory of Open Access Journals (Sweden)

    G. Colas des Francs

    2012-01-01

    Full Text Available Using either quasistatic approximation or exact Mie expansion, we characterize the localized surface plasmons supported by a metallic spherical nanoparticle. We estimate the quality factor Qn and define the effective volume Vn of the nth mode in such a way that coupling strength with a neighbouring dipolar emitter is proportional to the ratio Qn/Vn (Purcell factor. The role of Joule losses, far-field scattering, and mode confinement in the coupling mechanism is introduced and discussed with simple physical understanding, with particular attention paid to energy conservation.

  19. Mie plasmons: modes volumes, quality factors and coupling strengths (Purcell factor) to a dipolar emitter

    CERN Document Server

    Francs, G Colas des; Vincent, R; Bouhelier, A; Dereux, A

    2011-01-01

    Using either quasi-static approximation or exact Mie expansion, we characterize the localized surface plasmons supported by a metallic spherical nanoparticle. We estimate the quality factor $Q_n$ and define the effective volume $V_n$ of the $n^{th}$ mode in a such a way that coupling strength with a neighbouring dipolar emitter is proportional to the ratio $Q_n/V_n$ (Purcell factor). The role of Joule losses, far-field scattering and mode confinement in the coupling mechanism are introduced and discussed with simple physical understanding, with particular attention paid to energy conservation.

  20. A conceptual model of food quality management functions based on a techno-managerial approach

    NARCIS (Netherlands)

    Luning, P.A.; Marcelis, W.J.

    2007-01-01

    In agribusiness and food industry quality management problems are commonly approached by applying control systems and procedures. However, assuming predictable food systems and people following procedures seems too straightforward. This paper introduces a model of food quality management functions t

  1. A conceptual model of food quality management functions based on a techno-managerial approach

    NARCIS (Netherlands)

    Luning, P.A.; Marcelis, W.J.

    2007-01-01

    In agribusiness and food industry quality management problems are commonly approached by applying control systems and procedures. However, assuming predictable food systems and people following procedures seems too straightforward. This paper introduces a model of food quality management functions

  2. Nursing Home Care Quality: Insights from a Bayesian Network Approach

    Science.gov (United States)

    Goodson, Justin; Jang, Wooseung; Rantz, Marilyn

    2008-01-01

    Purpose: The purpose of this research is twofold. The first purpose is to utilize a new methodology (Bayesian networks) for aggregating various quality indicators to measure the overall quality of care in nursing homes. The second is to provide new insight into the relationships that exist among various measures of quality and how such measures…

  3. Service Quality in Higher Education Using an Enhanced SERVQUAL Approach

    Science.gov (United States)

    Tan, Kay C.; Kek, Sei W.

    2004-01-01

    Customer service and quality are driving forces in the business community. As higher educational institutions tussle for competitive advantage and high service quality, the evaluation of educational service quality is essential to provide motivation for and to give feedback on the effectiveness of educational plans and implementation. This…

  4. Nursing Home Care Quality: Insights from a Bayesian Network Approach

    Science.gov (United States)

    Goodson, Justin; Jang, Wooseung; Rantz, Marilyn

    2008-01-01

    Purpose: The purpose of this research is twofold. The first purpose is to utilize a new methodology (Bayesian networks) for aggregating various quality indicators to measure the overall quality of care in nursing homes. The second is to provide new insight into the relationships that exist among various measures of quality and how such measures…

  5. Quality Improvement in Virtual Higher Education: A Grounded Theory Approach

    Science.gov (United States)

    Mahdiuon, Rouhollah; Masoumi, Davoud; Farasatkhah, Maghsoud

    2017-01-01

    The article aims to explore the attributes of quality and quality improvement including the process and specific actions associated with these attributes--that contribute enhancing quality in Iranian Virtual Higher Education (VHE) institutions. A total of 16 interviews were conducted with experts and key actors in Iranian virtual higher education.…

  6. Measuring Service Quality in the Networked Environment: Approaches and Considerations.

    Science.gov (United States)

    Bertot, John Carlo

    2001-01-01

    This article offers a number of statistics and performance measures that libraries may find useful in determining the overall quality of their network-based services; identifies a number of service quality criteria; and provides a framework to assist librarians in selecting statistics and performance measures based on service quality criteria.…

  7. [Quality-of-life-related factors in adolescents].

    Science.gov (United States)

    Lima-Serrano, Marta; Martínez-Montilla, José Manuel; Guerra-Martín, María Dolores; Vargas-Martínez, Ana Magdalena; Lima-Rodríguez, Joaquín S

    2016-08-23

    To determine quality of life (QoL) and its relationship to lifestyles in adolescents in high schools. Cross-sectional, observational study with 256 students aged 12 to 17 in Seville (Spain). Multiple linear regression models were tested (p <0.05). The boys had higher scores in most of the QoL areas. The female gender was inversely related to physical, psychological, familial QoL areas and the general QoL index. Family functionality and performing physical activity were the factors most associated with better QoL in all areas. All multivariate models were statistically significant and explained from 11% of social QoL variability to 35% of the general QoL index. The findings could be useful for developing interventions to promote health in schools, with the objective of promoting healthy lifestyles and QoL. Copyright © 2016 SESPAS. Publicado por Elsevier España, S.L.U. All rights reserved.

  8. Anomalous Behavior of High Quality Factor Planar Superconducting Resonators

    Science.gov (United States)

    Megrant, Anthony; Chen, Zijun; Chiaro, Ben; Dunsworth, Andrew; Quintana, Chris; Campbell, Brooks; Kelly, Julian; Barends, Rami; Chen, Yu; Jeffrey, Evan; Mutus, Josh; Neill, Charles; O'Malley, Peter; Sank, Daniel; Vainsencher, Amit; Wenner, Jim; White, Ted; Bochmann, Jorg; Hoi, Iochun; Palmstrom, Christopher; Martinis, John; Cleland, Andrew

    2014-03-01

    Superconducting coplanar waveguide resonators have proven to be invaluable tools in studying some of the decoherence mechanisms found in superconducting qubits. Surface two-level states tend to dominate decoherence at temperatures below Tc/10 and at very low microwave powers, assuming loss through other channels (e.g. quasiparticles, vortices, and radiation loss) has been mitigated through proper shielding and design. I will present recent measurements of resonators whose behavior diverges significantly from the standard two-level state model at low temperatures and low excitation energies, resulting in startling behavior of the internal quality factor. This research was funded by the Office of the Director of National Intelligence (ODNI), Intelligence Advanced Research Projects Activity (IARPA), through the Army Research Office grant W911NF-09-1-0375.

  9. THE INSPECTION LIKE QUALITY FACTOR IN THE EDUCATIONAL SYSTEM

    Directory of Open Access Journals (Sweden)

    Joaquín Oliver Pozo

    2016-07-01

    Full Text Available The Inspection, along with other educational sectors, shapes from complementarity, coordination and communication between them, the architecture of the educational system. Each has its specificity and its own space in Education. The aim of this study is simply identify and define the location of the inspection into the education system, between educational administration and schools, and the "why" (their mission, and consistent with it, "which makes" (its functions and assignations. Mission and functions that take place in schools, at the sight of the Educational Administration and the society, through the Inspectorate as organization. Of the principles underlying this organization and of the communication, training, and technical and professional exchange that drives through their organizational structures, will depend its leadership in Education and to be seen as a quality factor.

  10. A Perfect Electromagnetic Cavity: High Quality Factor in Subwavelength Dimensions

    Science.gov (United States)

    Ginis, Vincent; Tassin, Philippe; Soukoulis, Costas M.; Veretennicoff, Irina

    2010-03-01

    Transformation optics has recently provided a new way to look at the interaction between light and matter. It uses the analogy between the macroscopic Maxwell's equations in complex dielectrics and the free-space Maxwell's equations on the background of an arbitrary metric to exploit the full potential of metamaterials, of which the most exciting examples are invisibility cloaks. In this contribution, we want to show how transformation optics can be applied to design a cavity with extraordinary properties. We have demonstrated theoretically the existence of eigenmodes whose wavelength is much larger than the characteristic dimensions of the cavity. Furthermore, our design avoids the bending losses observed in traditional microcavities, so that the quality factor is only limited by intrinsic absorption of the materials. Such a ``perfect cavity'' may be interesting for applications involving optical data storage or quantum optics, where it can be used to control the rate of spontaneous emission through the Purcell effect.

  11. Cherenkov loss factor of short relativistic bunches:general approach

    CERN Document Server

    Baturin, S S

    2013-01-01

    The interaction of short relativistic charged particle bunches with waveguides and other accelerator system components is a critical issue for the development of X-ray FELs (free electron lasers) and linear collider projects. Wakefield Cherenkov losses of short bunches have been studied previously for resistive wall, disk-loaded, corrugated and dielectric loaded waveguides. It was noted in various publications [1] that if the slowdown layer is thin, the Cherenkov loss factor of a short bunch does not depend on the guiding system material and is a constant for any given transverse cross section dimensions of the waveguides. In this paper, we consider a new approach to the analysis of loss factors for relativistic short bunches and formulate a general integral relation that allows calculation of the loss factor for a short relativistic bunch passing an arbitrary waveguide system. The loss factors calculated by this new method for various types of waveguides with arbitrary thickness slowdown layers, including in...

  12. Service Quality Robust Design by the Integration of Taguchi Experiments and SERVQUAL Approach in a Travel Agency

    Directory of Open Access Journals (Sweden)

    nassibeh janatyan

    2012-02-01

    Full Text Available The main purpose of this research is to address how robust design of service quality dimensions can be obtained. Service Quality Robust Design has been conducted by the integration of Taguchi Design of Experiments and SERVQUAL approach in Iran Travel Agency. Five basic dimensions of service quality, i.e. reliability, responsiveness, assurance, empathy, tangibles and price have been assumed as control factors. Response factor has been defined as two alternatives i the sum of customer expectations, and ii the sum of service quality gaps. In this investigation assumed that noise factor is not existed. The advantage of this paper is to improve the average and standard deviation simultaneously. Signal to noise ratio has been computed and the desired mix of the levels of service quality dimensions has been addressed. The main findings of this research includes the desired mix of the levels of service quality dimensions based on the sum of customer expectations and the desired mix of the levels of service quality dimensions based on the sum of service quality gaps. Comparing the two sets of findings helps the agency to analyze the cost of attracting new customers or retaining regular customers.

  13. Building the airplane in flight: an auditing approach to quality management system development.

    Science.gov (United States)

    Burson, M C

    2001-01-01

    In June of 2000, Maine DEP (in company with the other five New England states) found itself under EPA pressure to develop and document a quality management system by the end of the calendar year. In the frenzy that followed, the Department decided to use a private sector model for system development that called for a prospectively-focused QM plan that would be implemented through formal auditing. That is, instead of trying in advance to identify all the deficits in departmental quality management, and then assigning individuals and task groups to create structures to fill the gaps, Maine's QMP specifies the future desired system in broad terms. ME-DEP then uses its own cadre of trained auditors to assess current practice against the "condition expected" in the QMP, knowing that in many cases basic quality management practices will need to be developed. This approach assists program managers, particularly (but not exclusively) in areas sensitive to environmental data standards, in creating systems and practices that are rooted in reality, and that are perceived to add value to the Department's core work instead of just additional paperwork. Audit reports create a continuous feedback loop assuring that written procedures document actual operations. Finally, the results of auditing identify areas in which the QM system (and its plan) should be elaborated or refined, which leads to an iterative process by which quality approaches are infused in all areas of DEP operations. In the twelve months following EPA-Region I's initial approval of Maine's QMP, a total of seven audits were completed at various program levels, including two focused on critical QMP elements: Documents and Records; and Computer Hardware/Software. This paper will briefly describe the background and implementation of this approach; identify some of the factors which led to success; and describe, using selected examples, some of the early outcomes of the program.

  14. Fault Detection Observer Design for LSFDJ: A Factorization Approach

    Institute of Scientific and Technical Information of China (English)

    YANG Xiao-jun; WENG Zheng-xin; TIAN Zuo-hua

    2005-01-01

    Based on a new special co-inner-outer factorization, a factorization approach for design fault detection observer for LSFDJ was proposed. It is a simple state-space method and can deal with time-varying LSFDJ with sensor noise and sensor faults. The performance of the fault detection observer is optimized in an H∞ setting,where the ratio between the gains from disturbance and fault to residual respectively is minimized. The design parameters of the detection observer were given in terms of the solution to the Riccati differential equation with jumps.

  15. THE BILINGUAL INTERCULTURAL APPROACH AND ITS IMPACT ON THE QUALITY OF INDIGENOUS EDUCATION: CASE STUDY

    Directory of Open Access Journals (Sweden)

    José Viveros-Márquez

    2014-01-01

    Full Text Available This study presents the results of a systematic evaluation of the implementation of the Bilingual Intercultural approach (EIB in indigenous primary education and its impact on the quality of education, in the dimensions of equity, relevance, effectiveness and efficiency of education; in two indigenous regions of Mexico, with a comparative approach between the cases studied. The study is qualitative descriptive-explanatory section; the evaluation model CIPP (Context, Input, Process and Product and Shinkfield Stufflebeam (1987 was applied. It also appealed to the school ethnography, for data collection techniques of participant observation (class sessions focus group (teachers and parents, and semi-structured interview (managers and supervisors of each indigenous region. The results show that the EIB has had a limited impact on the quality of education; associated internal and external factors of each school and context; shape in the lack of effectiveness of the EIB in elementary school that significantly reduces the outcomes achieved by the indigenous teachers and education regarding bilingualism, multiculturalism and educational quality.

  16. [Factors to be considered in the production and introduction of high-quality protein foods].

    Science.gov (United States)

    Chávez, J F

    1980-03-01

    A wide variety of factors can influence the development, production and introduction of high-quality protein foods in a given country. Such factors can be grouped in three main areas: I. Factors depending upon the country itself. II. Factors related with the identity of the food and III. Factors inherent to the consumer. The role of the food industry and of the government are discussed in area I, and such aspects as improvement of staples, availability of raw materials, health programs and energy crisis are briefly commented. Area II covers product identity in relation to used ingredients. Nutritional quality and requirements as well as the danger of increasing the price of the product after being in the market are briefly discussed. The consumer's attitude, preferences and personal reactions towards the presentation of the food are covered in area III. Also marketing approach, promotion, labels and possible influence of the name are discussed. The launching of "incaparina" in Venezuela in 1964 and the reasons for its failure are commented from the different points of view covered in the above sections.

  17. Analysis of Factors Affecting the Quality of an E-commerce Website Using Factor Analysis

    Directory of Open Access Journals (Sweden)

    Saurabh Mishra

    2014-12-01

    Full Text Available The purpose of this study is to identify factors which affect the quality and effectiveness of an e commerce website which also majorly affect customer satisfaction and ultimately customer retention and loyalty. This research paper examines a set of 23 variables and integrates them into 4 factors which affect the quality of a website. An online questionnaire survey was conducted to generate statistics regarding the preferences of the e-commerce website users.The 23 variables taken from customer survey are generalized into 4 major factors using exploratory factor analysis which are content, navigation, services and interface design. The research majorly consists of the responses of students between the age group of 18-25 years and considers different B2C commercial websites. Identified variables are important with respect to the current competition in the market as service of an e-commerce website also play a major role in ensuring customer satisfaction. Further research in this domain can be done for websites’ version for mobile devices.

  18. An Integrated model for Product Quality Development—A case study on Quality functions deployment and AHP based approach

    Science.gov (United States)

    Maitra, Subrata; Banerjee, Debamalya

    2010-10-01

    Present article is based on application of the product quality and improvement of design related with the nature of failure of machineries and plant operational problems of an industrial blower fan Company. The project aims at developing the product on the basis of standardized production parameters for selling its products in the market. Special attention is also being paid to the blower fans which have been ordered directly by the customer on the basis of installed capacity of air to be provided by the fan. Application of quality function deployment is primarily a customer oriented approach. Proposed model of QFD integrated with AHP to select and rank the decision criterions on the commercial and technical factors and the measurement of the decision parameters for selection of best product in the compettitive environment. The present AHP-QFD model justifies the selection of a blower fan with the help of the group of experts' opinion by pairwise comparison of the customer's and ergonomy based technical design requirements. The steps invoved in implementation of the QFD—AHP and selection of weighted criterion may be helpful for all similar purpose industries maintaining cost and utility for competitive product.

  19. Characterization of a monoclonal antibody cell culture production process using a quality by design approach.

    Science.gov (United States)

    Horvath, Brian; Mun, Melissa; Laird, Michael W

    2010-07-01

    The goal of quality by design (QbD) in cell culture manufacturing is to develop manufacturing processes which deliver products with consistent critical quality attributes (CQAs). QbD approaches can lead to better process understanding through the use of process parameter risk ranking and statistical design of experiments (DOE). The QbD process starts with an analysis of process parameter risk with respect to CQAs and key performance indicators (KPIs). Initial DOE study designs and their factor test ranges are based on the outcomes of the process parameter risk ranking exercises. Initial DOE studies screen factors for significant influences on CQAs as well as characterize responses for process KPIs. In the case study provided here, multifactor process characterization studies using a scale-down model resulted in significant variation in charge heterogeneity of a monoclonal antibody (MAb) as measured by ion-exchange chromatography (IEC). Iterative DOE studies, using both screening and response surface designs, were used to narrow the operating parameter ranges so that charge heterogeneity could be controlled to an acceptable level. The data from the DOE studies were used to predict worst-case conditions, which were then verified by testing at those conditions. Using the approach described here, multivariate process parameter ranges were identified that yield acceptable CQA levels and that still provide operational flexibility for manufacturing.

  20. A fuzzy-logic based decision-making approach for identification of groundwater quality based on groundwater quality indices.

    Science.gov (United States)

    Vadiati, M; Asghari-Moghaddam, A; Nakhaei, M; Adamowski, J; Akbarzadeh, A H

    2016-12-15

    Due to inherent uncertainties in measurement and analysis, groundwater quality assessment is a difficult task. Artificial intelligence techniques, specifically fuzzy inference systems, have proven useful in evaluating groundwater quality in uncertain and complex hydrogeological systems. In the present study, a Mamdani fuzzy-logic-based decision-making approach was developed to assess groundwater quality based on relevant indices. In an effort to develop a set of new hybrid fuzzy indices for groundwater quality assessment, a Mamdani fuzzy inference model was developed with widely-accepted groundwater quality indices: the Groundwater Quality Index (GQI), the Water Quality Index (WQI), and the Ground Water Quality Index (GWQI). In an effort to present generalized hybrid fuzzy indices a significant effort was made to employ well-known groundwater quality index acceptability ranges as fuzzy model output ranges rather than employing expert knowledge in the fuzzification of output parameters. The proposed approach was evaluated for its ability to assess the drinking water quality of 49 samples collected seasonally from groundwater resources in Iran's Sarab Plain during 2013-2014. Input membership functions were defined as "desirable", "acceptable" and "unacceptable" based on expert knowledge and the standard and permissible limits prescribed by the World Health Organization. Output data were categorized into multiple categories based on the GQI (5 categories), WQI (5 categories), and GWQI (3 categories). Given the potential of fuzzy models to minimize uncertainties, hybrid fuzzy-based indices produce significantly more accurate assessments of groundwater quality than traditional indices. The developed models' accuracy was assessed and a comparison of the performance indices demonstrated the Fuzzy Groundwater Quality Index model to be more accurate than both the Fuzzy Water Quality Index and Fuzzy Ground Water Quality Index models. This suggests that the new hybrid fuzzy

  1. Quality control with R an ISO standards approach

    CERN Document Server

    Cano, Emilio L; Prieto Corcoba, Mariano

    2015-01-01

    Presenting a practitioner's guide to capabilities and best practices of quality control systems using the R programming language, this volume emphasizes accessibility and ease-of-use through detailed explanations of R code as well as standard statistical methodologies. In the interest of reaching the widest possible audience of quality-control professionals and statisticians, examples throughout are structured to simplify complex equations and data structures, and to demonstrate their applications to quality control processes, such as ISO standards. The volume balances its treatment of key aspects of quality control, statistics, and programming in R, making the text accessible to beginners and expert quality control professionals alike. Several appendices serve as useful references for ISO standards and common tasks performed while applying quality control with R.

  2. Advancement in modern approaches to mineral production quality control

    Science.gov (United States)

    Freidina, EV; Botvinnik, AA; Dvornikova, AN

    2017-02-01

    The natural resource potential of mineral deposits is represented by three categories: upside, attainable and investment. A modern methodology is proposed in this paper for production quality control, and its tools aimed at ensuring agreement between the product quality and the market requirements are described. The definitions of the costs of the product quality compliance and incompliance with the consumer requirements are introduced; the latter is suggested to use in evaluating resource potential of mineral deposits at a certain degree of probability.

  3. Determining organizational information needs: the Critical Success Factors approach.

    Directory of Open Access Journals (Sweden)

    2001-01-01

    Full Text Available Reports on a series of investigations in the UK and Finland, in both academic and business institutions. The Critical Success Factors approach is defined and explored as a means of determining the information needs of organizations, rather than of individuals. Concludes that such use is appropriate and productive, enabling the identification of types of information that may aid the organization in its strategic policy making to achieve competitive advantage.

  4. Shear dependent nonlinear vibration in a high quality factor single crystal silicon micromechanical resonator

    Science.gov (United States)

    Zhu, H.; Shan, G. C.; Shek, C. H.; Lee, J. E.-Y.

    2012-07-01

    The frequency response of a single crystal silicon resonator under nonlinear vibration is investigated and related to the shear property of the material. The shear stress-strain relation of bulk silicon is studied using a first-principles approach. By incorporating the calculated shear property into a device-level model, our simulation closely predicts the frequency response of the device obtained by experiments and further captures the nonlinear features. These results indicate that the observed nonlinearity stems from the material's mechanical property. Given the high quality factor (Q) of the device reported here (˜2 × 106), this makes it highly susceptible to such mechanical nonlinear effects.

  5. Factors Influencing the Quality of Encapsulation in Rock Bolting

    Science.gov (United States)

    Aziz, Naj; Craig, Peter; Mirzaghorbanali, Ali; Nemcik, Jan

    2016-08-01

    Bolt installation quality is influenced by various factors, some are well known and others are less recognised. A programme of field and laboratory studies was undertaken to examine various factors of relevance to the load transfer mechanism between the bolt, resin and rock to ensure test methods truly represent field performance. Short encapsulation tests were undertaken as part of the Australian Coal Association Research Program (ACARP) funded project (C21011) with the ultimate aim of developing standard test methods for assessing bolt encapsulation with chemical resin anchor installations. The field study consisted of a series of Short Encapsulation Pull Tests (SEPT) carried out in three mines with different geological conditions to determine the most representative and practical method of SEPT. Additional field work included installation of bolts into threaded steel tubes for subsequent removal and laboratory evaluation. A series of pull tests was carried out by installing bolts in overhead rig mounted sandstone block, cast in concrete with controlled encapsulation length. Factors of importance considered included; borehole diameter, resin annulus thickness, installation time (including bolt spin to the back and "spin at back"), the effect of gloving and hole over drill. It was found that the borehole diameter had a detrimental effect on the encapsulation bonding strength. Bolt installation time of approximately 10 s constituted an acceptable time for effective bolt installation and within the resin manufacturers recommended time of 14 s. Maintaining constant length of encapsulation was paramount for obtaining consistency and repeatability of the test results. Finally, a numerical simulation study was carried out to assess the capabilities of FLAC 2D software in simulating the pull testing of rock bolts.

  6. Quality by design approach for optimizing the formulation and physical properties of extemporaneously prepared orodispersible films.

    Science.gov (United States)

    Visser, J Carolina; Dohmen, Willem M C; Hinrichs, Wouter L J; Breitkreutz, Jörg; Frijlink, Henderik W; Woerdenbag, Herman J

    2015-05-15

    The quality by design (QbD) approach was applied for optimizing the formulation of extemporaneously prepared orodispersible films (ODFs) using Design-Expert® Software. The starting formulation was based on earlier experiments and contained the film forming agents hypromellose and carbomer 974P and the plasticizer glycerol (Visser et al., 2015). Trometamol and disodium EDTA were added to stabilize the solution. To optimize this formulation a quality target product profile was established in which critical quality attributes (CQAs) such as mechanical properties and disintegration time were defined and quantified. As critical process parameters (CPP) that were evaluated for their effect on the CQAs the percentage of hypromellose and the percentage of glycerol as well as the drying time were chosen. Response surface methodology (RMS) was used to evaluate the effects of the CPPs on the CQAs of the final product. The main factor affecting tensile strength and Young's modulus was the percentage of glycerol. Elongation at break was mainly influenced by the drying temperature. Disintegration time was found to be sensitive to the percentage of hypromellose. From the results a design space could be created. As long as the formulation and process variables remain within this design space, a product is obtained with desired characteristics and that meets all set quality requirements.

  7. Motivational factors as predictors of student approach to learning

    DEFF Research Database (Denmark)

    Lassesen, Berit Irene

    Background and aim: Research indicates that both self-efficacy and test anxiety may influence student performance. There is also evidence to suggest that students´ approach to learn, i.e. whether they adopt a deep or surface approach influence learning outcome. There is, however, little research...... exploring the possible influences of self-efficacy and test anxiety on study behavior in higher education. Increasing our knowledge about these associations could improve our understanding of the processes and mechanisms involved in learning and academic performance. Methods: 1181 undergraduate and graduate...... and multivariate hierarchical regression analyses, adjusting for the remaining variables. Results: Both self-efficacy, test-anxiety, and perception of the teaching environment appeared to be strong independent predictors of student approaches to learning even when controlling for other motivational factors...

  8. Motivational factors as predictors of student approach to learning

    DEFF Research Database (Denmark)

    Lassesen, Berit Irene

    Background and aim: Research indicates that both self-efficacy and test anxiety may influence student performance. There is also evidence to suggest that students´ approach to learn, i.e. whether they adopt a deep or surface approach influence learning outcome. There is, however, little research...... exploring the possible influences of self-efficacy and test anxiety on study behavior in higher education. Increasing our knowledge about these associations could improve our understanding of the processes and mechanisms involved in learning and academic performance. Methods: 1181 undergraduate and graduate...... and multivariate hierarchical regression analyses, adjusting for the remaining variables. Results: Both self-efficacy, test-anxiety, and perception of the teaching environment appeared to be strong independent predictors of student approaches to learning even when controlling for other motivational factors...

  9. The systems of certification of quality in the industry: factors that determine their implantation; Los sistemas certificados de calidad en la industria: factores que determinan su implantacion

    Energy Technology Data Exchange (ETDEWEB)

    Lopez-Rodriguez, F.; Alvarez-Martinez, P.; Guijarro-Merelles, F.; Mena-Nieto, A.

    2009-07-01

    Certified quality management systems represent one of the most competitive strategies used in industry today. Its general use, has motivated the study of the different factor that take part in their implementation. Numerous studies approach this subject but without valuing the importance of each factor. this work is focused on determining the influence of each one of the factors during the implementation of certified QMS according to norm ISO 9000. Once collected the data in order to hierarchize them, Rash's model was adopted to the present study. We observed that the internal factors, such as having a good organizational structure and having dearly defined processes, were the most significant in the certification process. On the other hand, external type factors, such as customer pressure or the quality level of the competition, were less significant to improve the certification process. (Author) 16 refs.

  10. Analytical approaches to quality assurance and quality control in rangeland monitoring data

    Science.gov (United States)

    Producing quality data to support land management decisions is the goal of every rangeland monitoring program. However, the results of quality assurance (QA) and quality control (QC) efforts to improve data quality are rarely reported. The purpose of QA and QC is to prevent and describe non-sampling...

  11. Nonrelativistic QED approach to the bound-electron g factor

    CERN Document Server

    Pachucki, K; Yerokhin, V A

    2004-01-01

    Within a systematic approach based on nonrelativistic quantum electrodynamics (NRQED), we derive the one-loop self-energy correction of order alpha (Zalpha)^4 to the bound-electron g factor. In combination with numerical data, this analytic result improves theoretical predictions for the self-energy correction for carbon and oxygen by an order of magnitude. Basing on one-loop calculations, we obtain the logarithmic two-loop contribution of order alpha^2 (Zalpha)^4 ln[(Zalpha)^-2] and the dominant part of the corresponding constant term. The results obtained improve the accuracy of the theoretical predictions for the 1S bound-electron g factor and influence the value of the electron mass determined from g factor measurements.

  12. Nonrelativistic QED Approach to the Bound-Electron g Factor

    Science.gov (United States)

    Pachucki, Krzysztof; Jentschura, Ulrich D.; Yerokhin, Vladimir A.

    2004-10-01

    Within a systematic approach based on nonrelativistic quantum electrodynamics, we derive the one-loop self-energy correction of order α(Zα)4 to the bound-electron g factor. In combination with numerical data, this analytic result improves theoretical predictions for the self-energy correction for carbon and oxygen by an order of magnitude. Basing on one-loop calculations, we obtain the logarithmic two-loop contribution of order α2(Zα)4ln([(Zα)-2] and the dominant part of the corresponding constant term. The results obtained improve the accuracy of the theoretical predictions for the 1S bound-electron g factor and influence the value of the electron mass determined from g-factor measurements.

  13. A Context-Based Approach to E-Learning Quality

    DEFF Research Database (Denmark)

    Kjærgaard, Hanne Wacher; Kjeldsen, Lars Peter

    2011-01-01

    The aim of the article is to provide new, operational knowledge concerning implementation and quality assurance of e-learning. This is done through the merging of the two models presented in Högskoleverket’s report (Högskoleverket, 2008) and the article, ”The quality of evaluation is enhanced, when...... skills required....

  14. The impact of quality on store loyalty : A contingency approach

    NARCIS (Netherlands)

    Odekerken-Schroder, G; De Wulf, K; Kasper, H; Kleijnen, M; Hoekstra, J; Commandeur, H

    2001-01-01

    This study's prime interest is to assist retail managers in deciding where they are likely to get the greatest response to their expenditures on quality improvement. An empirical test involving 287 consumers reporting on a wide array of stores assesses whether the relationship between three quality

  15. The impact of quality on store loyalty : A contingency approach

    NARCIS (Netherlands)

    Odekerken-Schroder, G; De Wulf, K; Kasper, H; Kleijnen, M; Hoekstra, J; Commandeur, H

    This study's prime interest is to assist retail managers in deciding where they are likely to get the greatest response to their expenditures on quality improvement. An empirical test involving 287 consumers reporting on a wide array of stores assesses whether the relationship between three quality

  16. Identifying Quality Indicators of SAE and FFA: A Delphi Approach

    Science.gov (United States)

    Jenkins, Charles Cordell, III; Kitchel, Tracy

    2009-01-01

    The purpose of this study was to determine quality indicators for SAE and FFA according to 36 experts across the United States. This is a part of a larger study looking at all components of the traditional three-circle model. The study utilized the Delphi technique to garner expert opinion about quality indicators in Agricultural Education. For…

  17. Framing perceived service quality and related constructs : A multilevel approach

    NARCIS (Netherlands)

    Roest, H.C.A.; Koelemeijer, K.

    1993-01-01

    Despite many publications on perceived service quality, the position of the construct relative to other key constructs in marketing/consumer behavior remains vague. This paper tries to bring conceptual clarity with regard to the relationships between perceived service quality, customer satisfaction/

  18. Artificial Intelligence Approach to Support Statistical Quality Control Teaching

    Science.gov (United States)

    Reis, Marcelo Menezes; Paladini, Edson Pacheco; Khator, Suresh; Sommer, Willy Arno

    2006-01-01

    Statistical quality control--SQC (consisting of Statistical Process Control, Process Capability Studies, Acceptance Sampling and Design of Experiments) is a very important tool to obtain, maintain and improve the Quality level of goods and services produced by an organization. Despite its importance, and the fact that it is taught in technical and…

  19. Principal Component Clustering Approach to Teaching Quality Discriminant Analysis

    Science.gov (United States)

    Xian, Sidong; Xia, Haibo; Yin, Yubo; Zhai, Zhansheng; Shang, Yan

    2016-01-01

    Teaching quality is the lifeline of the higher education. Many universities have made some effective achievement about evaluating the teaching quality. In this paper, we establish the Students' evaluation of teaching (SET) discriminant analysis model and algorithm based on principal component clustering analysis. Additionally, we classify the SET…

  20. A Novel Approach for Quality Education towards Industry Expectations

    Science.gov (United States)

    Santhiyakumari, N.; Babu, C.; Gomathi, C.; Rajesh, K.; Shenbagapriya, M.

    2014-01-01

    This paper presents a new method to improve the quality in technical education in order to meet the industry expectations. The quality of education and training being imparted in the technical education institutions varies from excellent to poor, with some institutions comparing favourably with the best in the world. Few others are suffering from…

  1. The design of quality systems : A contingency approach

    NARCIS (Netherlands)

    van der Bij, JD; Broekhuis, H

    1998-01-01

    While developing quality management, many organizations nowadays focus on the control and improvement of their work processes, the systematic use of relevant information pertaining to the performance of the work processes, and prevention. In this stage, the design of a quality system is important fo

  2. Framing perceived service quality and related constructs : A multilevel approach

    NARCIS (Netherlands)

    Roest, H.C.A.; Koelemeijer, K.

    1993-01-01

    Despite many publications on perceived service quality, the position of the construct relative to other key constructs in marketing/consumer behavior remains vague. This paper tries to bring conceptual clarity with regard to the relationships between perceived service quality, customer satisfaction/

  3. QUALITY MANAGEMENT PRINCIPLES – AN APPROACH IN HEALTHCARE INSTITUTIONS

    Directory of Open Access Journals (Sweden)

    Kristina ZGODAVOVA

    2007-01-01

    Full Text Available The problems of quality management systems development don´t seem to be interesting for healthcare institutions (HCI at a glance. But a lot of managers and employees of HCI (including physicians have already understood that their organizations also operate in environment, which asks for quality, performance and effectiveness. The quality management systems create a strategic framework in which every organization can meet these requirements. In case of HCI the term “quality management system” can be understood as a part of overall management system that is to guarantee the highest customer satisfaction in the most effective manner, especially by following functions: a assuring the highest service quality for patients; b creating environment oriented to continual improvement of processes and c doing it with the lowest expenditure.

  4. Importance of patient-centered approach in ensuring quality of post-fracture rehabilitation for working aged people

    DEFF Research Database (Denmark)

    Lindahl, Marianne Pia; Teljigovic, Sanel; Jensen, Lars Heegaard

    2016-01-01

    therapists from hospitals, municipalities and private practice were included in the study. Grounded theory was used to analyze data and develop a theory about quality in the rehabilitation process. RESULTS: Partnership was identified as the core category with continuity of rehabilitation and patient......BACKGROUND: Quality in rehabilitation is important for recovery and return to work for people at working age, who sustain fractures, but there is limited information about what constitutes quality in rehabilitation. OBJECTIVE: To identify factors that therapists and patients define as quality...... in decisions about the therapeutic methods had the same effect. CONCLUSION: Quality in rehabilitation was enhanced in all its dimensions namely structure, process and outcome when therapists used the patient-centred approach and addressed the patient’s overall situation....

  5. A feasibility study of the implementation of total quality management based on soft factor

    Directory of Open Access Journals (Sweden)

    Arash Shahin

    2011-07-01

    Full Text Available Purpose:  The aim of this paper is to examine the feasibility of implementing TQM based on soft factors, which can influence the successful implementation of TQM.Design/methodology/approach: A framework has been developed for the TQM soft factors based on literature review and respectively, questionnaires which are directly related to the addressed factors have been designed and distributed to the employees of an engineering service company as the main enablers of improving the effectiveness of TQM.Findings: The findings imply that committed leadership, closer customer relationship, benchmarking and process improvement have the most correlations amongst the TQM soft factors. Training is the only factor which is not correlated to other soft factors. Leadership has also the highest value among the soft factors.Research limitations/implications: The proposed framework is costly and time consuming due to the large number of questions it holds. In this study, it is assumed that sub factors have the same importance. But there is a possibility in which these subdivisions do not have the same relative importance weight. The study is also limited to one company and therefore, the findings should not be generalized.Practical implications: The proposed TQM soft factors framework can be useful for those organizations which consider TQM as an integrated quality management system as the major foundation for achievement of competitive advantage.Originality/value: A comprehensive framework for TQM soft factors has been presented since it involves almost all of the soft factors addressed in the literature.

  6. Broad target chemical screening approach used as tool for rapid assessment of groundwater quality

    NARCIS (Netherlands)

    ter Laak, T.L.; Puijker, L.M.; van Leerdam, J.A.; Raat, K.J.; Kolkman, A.; de Voogt, P.; van Wezel, A.P.

    2012-01-01

    The chemical water quality is often assessed by screening for a limited set of target chemicals. This ‘conventional’ target analysis approach inevitably misses chemicals present in the samples. In this study a ‘broad’ target screening approach for water quality assessment using high resolution and a

  7. Factors influencing success in quality-improvement collaboratives: development and psychometric testing of an instrument

    Directory of Open Access Journals (Sweden)

    Grol Richard PTM

    2010-10-01

    Full Text Available Abstract Background To increase the effectiveness of quality-improvement collaboratives (QICs, it is important to explore factors that potentially influence their outcomes. For this purpose, we have developed and tested the psychometric properties of an instrument that aims to identify the features that may enhance the quality and impact of collaborative quality-improvement approaches. The instrument can be used as a measurement instrument to retrospectively collect information about perceived determinants of success. In addition, it can be prospectively applied as a checklist to guide initiators, facilitators, and participants of QICs, with information about how to perform or participate in a collaborative with theoretically optimal chances of success. Such information can be used to improve collaboratives. Methods We developed an instrument with content validity based on literature and the opinions of QIC experts. We collected data from 144 healthcare professionals in 44 multidisciplinary improvement teams participating in two QICs and used exploratory factor analysis to assess the construct validity. We used Cronbach's alpha to ascertain the internal consistency. Results The 50-item instrument we developed reflected expert-opinion-based determinants of success in a QIC. We deleted nine items after item reduction. On the basis of the factor analysis results, one item was dropped, which resulted in a 40-item questionnaire. Exploratory factor analysis showed that a three-factor model provided the best fit. The components were labeled 'sufficient expert team support', 'effective multidisciplinary teamwork', and 'helpful collaborative processes'. Internal consistency reliability was excellent (alphas between .85 and .89. Conclusions This newly developed instrument seems a promising tool for providing healthcare workers and policy makers with useful information about determinants of success in QICs. The psychometric properties of the instrument are

  8. The Astro-WISE approach to quality control for astronomical data

    NARCIS (Netherlands)

    Mc Farland, John; Helmich, Ewout M.; Valentijn, Edwin A.

    2013-01-01

    We present a novel approach to quality control during the processing of astronomical data. Quality control in the Astro-WISE Information System is integral to all aspects of data handing and provides transparent access to quality estimators for all stages of data reduction from the raw image to the

  9. The Astro-WISE approach to quality control for astronomical data

    NARCIS (Netherlands)

    Mc Farland, John; Helmich, Ewout M.; Valentijn, Edwin A.

    We present a novel approach to quality control during the processing of astronomical data. Quality control in the Astro-WISE Information System is integral to all aspects of data handing and provides transparent access to quality estimators for all stages of data reduction from the raw image to the

  10. Factor Structure of Quality of Life: The Lehman Interview.

    Science.gov (United States)

    Goodman, Marianne; Hull, James W.; Terkelsen, Kenneth G.; Smith, Thomas E.; Anthony, Donna

    1997-01-01

    This study of 67 chronically mentally ill outpatients examined subjective Quality of Life Scores from A. Lehman's Quality of Life Interview. Results suggest a model of life satisfaction in which instrumental and affiliative needs comprise significant portions of life satisfaction. Implications for other quality of life and life satisfaction…

  11. Factor Structure of Quality of Life: The Lehman Interview.

    Science.gov (United States)

    Goodman, Marianne; Hull, James W.; Terkelsen, Kenneth G.; Smith, Thomas E.; Anthony, Donna

    1997-01-01

    This study of 67 chronically mentally ill outpatients examined subjective Quality of Life Scores from A. Lehman's Quality of Life Interview. Results suggest a model of life satisfaction in which instrumental and affiliative needs comprise significant portions of life satisfaction. Implications for other quality of life and life satisfaction…

  12. Factors associated with poor sleep quality in women with cancer.

    Science.gov (United States)

    Mansano-Schlosser, Thalyta Cristina; Ceolim, Maria Filomena

    2017-03-02

    to analyze the factors associated with poor sleep quality, its characteristics and components in women with breast cancer prior to surgery for removing the tumor and throughout the follow-up. longitudinal study in a teaching hospital, with a sample of 102 women. The following were used: a questionnaire for sociodemographic and clinical characterization, the Pittsburgh Sleep Quality Index; the Beck Depression Inventory; and the Herth Hope Scale. Data collection covered from prior to the surgery for removal of the tumor (T0) to T1, on average 3.2 months; T2, on average 6.1 months; and T3, on average 12.4 months. Descriptive statistics and the Generalized Estimating Equations model were used. depression and pain contributed to the increase in the score of the Pittsburgh Sleep Quality Index, and hope, to the reduction of the score - independently - throughout follow-up. Sleep disturbances were the component with the highest score throughout follow-up. the presence of depression and pain, prior to the surgery, contributed to the increase in the global score of the Pittsburgh Sleep Quality Index, which indicates worse quality of sleep throughout follow-up; greater hope, in its turn, influenced the reduction of the score of the Pittsburgh Sleep Quality Index. analizar los factores asociados a la mala calidad del sueño, sus características y componentes en mujeres con cáncer de mama, antes de la cirugía de retirada del tumor y a lo largo del seguimiento. estudio longitudinal, en hospital universitario con muestra de 102 mujeres. Fueron utilizados: un cuestionario de caracterización sociodemográfica y clínica; el Índice de Calidad del Sueño de Pittsburgh; el Inventario de Depresión de Beck; y la Escala de Esperanza de Herth. La recolección comprendió los momentos: antes de la cirugía de retirada del tumor (T0), en (T1) en promedio 3,2 meses, en (T2) en promedio 6,1 meses y en (T3) en promedio 12,4 meses. Se utilizó estadística descriptiva y el modelo de

  13. High Quality Factor Platinum Silicide Microwave Kinetic Inductance Detectors

    CERN Document Server

    Szypryt, P; Ulbricht, G; Bumble, B; Meeker, S R; Bockstiegel, C; Walter, A B

    2016-01-01

    We report on the development of Microwave Kinetic Inductance Detectors (MKIDs) using platinum silicide as the sensor material. MKIDs are an emerging superconducting detector technology, capable of measuring the arrival times of single photons to better than two microseconds and their energies to around ten percent. Previously, MKIDs have been fabricated using either sub-stoichiometric titanium nitride or aluminum, but TiN suffers from spatial inhomogeneities in the superconducting critical temperature and Al has a low kinetic inductance fraction, causing low detector sensitivity. To address these issues, we have instead fabricated PtSi microresonators with superconducting critical temperatures of 944$\\pm$12~mK and high internal quality factors ($Q_i \\gtrsim 10^6$). These devices show typical quasiparticle lifetimes of $\\tau_{qp} \\approx 30$--$40~\\mu$s and spectral resolution, $R = \\lambda / \\Delta \\lambda$, of 8 at 406.6~nm. We compare PtSi MKIDs to those fabricated with TiN and detail the substantial advanta...

  14. Implementing Composite Quality Metrics for Bipolar Disorder: Towards a More Comprehensive Approach to Quality Measurement

    Science.gov (United States)

    Kilbourne, Amy M.; Farmer, Carrie; Welsh, Deborah; Pincus, Harold Alan; Lasky, Elaine; Perron, Brian; Bauer, Mark S.

    2011-01-01

    Objective We implemented a set of processes of care measures for bipolar disorder that reflect psychosocial, patient preference, and continuum of care approaches to mental health, and examined whether veterans with bipolar disorder receive care concordant with these practices. Method Data from medical record reviews were used to assess key processes of care for 433 VA mental health outpatients with bipolar disorder. Both composite and individual processes of care measures were operationalized. Results Based on composite measures, 17% had documented assessment of psychiatric symptoms (e.g., psychotic, hallucinatory), 28% had documented patient treatment preferences (e.g., reasons for treatment discontinuation), 56% had documented substance abuse and psychiatric comorbidity assessment, and 62% had documentation of adequate cardiometabolic assessment. No-show visits were followed up 20% of the time and monitoring of weight gain was noted in only 54% of the patient charts. In multivariate analyses, history of homelessness (OR=1.61; 95% CI=1.05-2.46) and nonwhite race (OR=1.74; 95%CI=1.02-2.98) were associated with documentation of psychiatric symptoms and comorbidities, respectively. Conclusions Only half of patients diagnosed with bipolar disorder received care in accordance with clinical practice guidelines. High quality treatment of bipolar disorder includes not only adherence to treatment guidelines but also patient-centered care processes. PMID:21112457

  15. Assessing quality in software development: An agile methodology approach

    National Research Council Canada - National Science Library

    V Rodríguez-Hernández; M C Espino-Gudiño; J L González-Pérez; J Gudiño-Bazaldúa; V M Castaño

    2015-01-01

      A novel methodology, result of 10 years of in-field testing, which makes possible the convergence of different types of models and quality standards for Engineering and Computer Science Faculties, is presented...

  16. An Approach to Establishing International Quality Standards for Medical Travel

    Directory of Open Access Journals (Sweden)

    Ondřej eKácha

    2016-03-01

    Full Text Available Traveling abroad to receive a non-elective treatment is expanding each year. Such rising popularity of medical travel and the absence of clear minimum quality requirements in this area urgently calls for setting international standards to ensure good practice and patient safety. The aim of this study is to identify the key domains in medical travel where such quality standards should be established. Drawing from the evidence-based OECD framework and an extensive literature review, this study proposes three critical areas for international quality standards in medical travel: minimum standards of health care facilities and third-party agencies, financial responsibility and patient-centeredness. Several cultural challenges are subsequently introduced that may pose a barrier to the development of the guidelines and should be additionally taken into consideration. Establishing international quality standards in medical travel enhances the benefits to patients and providers, which is urgently needed given the rapid growth in this industry.

  17. Framing perceived service quality and related constructs : A multilevel approach

    OpenAIRE

    Roest, H.C.A.; Koelemeijer, K.

    1993-01-01

    Despite many publications on perceived service quality, the position of the construct relative to other key constructs in marketing/consumer behavior remains vague. This paper tries to bring conceptual clarity with regard to the relationships between perceived service quality, customer satisfaction/ dissatisfaction, attitude, and repurchase intention. An integrated framework is presented based on a review of the literature on the each of the relevant constructs. Central issue in this integrat...

  18. MODERN THEORETICAL APPROACHES CREDIT PORTFOLIO QUALITY MANAGEMENT OF COMMERCIAL BANK

    Directory of Open Access Journals (Sweden)

    Victoria Lisnic

    2016-12-01

    Full Text Available Credit portfolio management means the totality of financial and economic decisions realization aimed at achieving optimal ratio of performance indicators of loan portfolio. If low-quality loans increase, the reduction of productive assets volume and, respectively, profitability from banking lending. In extreme cases a such situation could lead to bank bankruptcy. At present bank loan portfolio quality assessment is an important component of bank management.

  19. De Factorisatione Numerorum I : An Analytic Approach to Subexponential Factoring

    CERN Document Server

    Sica, Francesco

    2009-01-01

    We introduce a novel glance at factoring. In this work, we are chiefly concerned with the asymptotic aspect of the method, as we will show that this approach \\emph{almost} allows to deterministically factor a RSA modulus $N=pq$ in $O\\bigl(\\exp({\\log^\\epsilon N})\\bigr)$ bit operations for any $\\epsilon>0$. An important feature of this approach is that any bound is absolutely proven and does not rely on any assumption. The technique broached here departs from any know (at least to the author) factoring method. It is based on the study of carefully selected multiplicative functions in order to approximate them at $N$. Using their generating functions, expressed in terms of the Riemann zeta function, together with their functional equations, we derive an analytic identity which involves the computation of a family of series, which we call the \\emph{singular series} (as they embody an arithmetic information in analytic disguise), depending "minimally" on $N$. We finally show how the approximate computation of a ma...

  20. Working toward quality in obstetric anesthesia: a business approach.

    Science.gov (United States)

    Lynde, Grant C

    2017-06-01

    Physicians are increasingly required to demonstrate that they provide quality care. How does one define quality? A significant body of literature in industries outside of health care provides guidance on how to define appropriate metrics, create teams to troubleshoot problem areas, and sustain those improvements. The modern quality movement in the United States began in response to revolutionary gains in both quality and productivity in Japanese manufacturing in the 1980's. Applying these lessons to the healthcare setting has been slow. Hospitals are only now introducing tools such as failure mode and effect analysis, Lean and Six Sigma into their quality divisions and are seeing significant cost reductions and outcomes improvements. The review will discuss the process for creating an effective quality program for an obstetric anesthesia division. Sustainable improvements in delivered care need to be based on an evaluation of service line needs, defining appropriate metrics, understanding current process flows, changing and measuring those processes, and developing mechanisms to ensure the new processes are maintained.

  1. Ranking factors affecting the quality of banking services using analytic network process

    Directory of Open Access Journals (Sweden)

    Hooman Pourmohammad

    2016-06-01

    Full Text Available This paper seeks to identify the priority of factors affecting the quality of banking services in Bank Saderat Iran for better allocation of resources to enhance the quality of its banking services. The study develops a fuzzy method to handle uncertainty associated with the data and using analytical network process (ANP ranks different factors influencing on service quality. The results have indicated that the quality of e-services (ESQ is the most important factor followed by the quality of banking services agility (ASQ, the service system quality (SSQ, and the behavioral service qualities (BSQ. Moreover, the employees’ competence and skills, the reliability of the electronic system and the reliability of the service system, an impeccability banking system integrity and accountability instruments are among other effective factors influencing on the quality of banking services.

  2. High quality factor polymeric Fabry-Perot resonators utilizing a polymer waveguide.

    Science.gov (United States)

    Tadayon, Mohammad Amin; Baylor, Martha-Elizabeth; Ashkenazi, Shai

    2014-03-10

    Optical resonators are used in a variety of applications ranging from sensors to lasers and signal routing in high volume communication networks. Achieving a high quality (Q) factor is necessary for higher sensitivity in sensing applications and for narrow linewidth light emission in most lasing applications. In this work, we propose a new approach to achieve a very high Q-factor in polymeric Fabry-Perot resonators by conquering light diffraction inside the optical cavity. This can be achieved by inducing a refractive index feature inside the optical cavity that simply creates a waveguide between the two mirrors. This approach eliminates diffraction loss from the cavity and therefore the Q-factor is only limited by mirror loss and absorption. To demonstrate this claim, a device has been fabricated consisting of two dielectric Bragg reflectors with a 100 μm layer of photosensitive polymer between them. The refractive index of this polymer can be modified utilizing standard photo-lithography processes. The measured finesse of the fabricated device was 692 and the Q-factor was 55000.

  3. Shear wave velocity versus quality factor: results from seismic noise recordings

    Science.gov (United States)

    Boxberger, Tobias; Pilz, Marco; Parolai, Stefano

    2017-08-01

    The assessment of the shear wave velocity (vs) and shear wave quality factor (Qs) for the shallow structure below a site is necessary to characterize its site response. In the past, methods based on the analysis of seismic noise have been shown to be very efficient for providing a sufficiently accurate estimation of the vs versus depth at reasonable costs for engineering seismology purposes. In addition, a slight modification of the same method has proved to be able to provide realistic Qs versus depth estimates. In this study, data sets of seismic noise recorded by microarrays of seismic stations in different geological environments of Europe and Central Asia are used to calculate both vs and Qs versus depth profiles. Analogous to the generally adopted approach in seismic hazard assessment for mapping the average shear wave velocity in the uppermost 30 m (vs30) as a proxy of the site response, this approach was also applied to the quality factor within the uppermost 30 m (Qs30). A slightly inverse correlation between both parameters is found based on a methodological consistent determination for different sites. Consequently, a combined assessment of vs and Qs by seismic noise analysis has the potential to provide a more comprehensive description of the geological structure below a site.

  4. The consistency approach for quality control of vaccines - a strategy to improve quality control and implement 3Rs.

    Science.gov (United States)

    De Mattia, Fabrizio; Chapsal, Jean-Michel; Descamps, Johan; Halder, Marlies; Jarrett, Nicholas; Kross, Imke; Mortiaux, Frederic; Ponsar, Cecile; Redhead, Keith; McKelvie, Jo; Hendriksen, Coenraad

    2011-01-01

    Current batch release testing of established vaccines emphasizes quality control of the final product and is often characterized by extensive use of animals. This report summarises the discussions of a joint ECVAM/EPAA workshop on the applicability of the consistency approach for routine release of human and veterinary vaccines and its potential to reduce animal use. The consistency approach is based upon thorough characterization of the vaccine during development and the principle that the quality of subsequent batches is the consequence of the strict application of a quality system and of a consistent production of batches. The concept of consistency of production is state-of-the-art for new-generation vaccines, where batch release is mainly based on non-animal methods. There is now the opportunity to introduce the approach into established vaccine production, where it has the potential to replace in vivo tests with non-animal tests designed to demonstrate batch quality while maintaining the highest quality standards. The report indicates how this approach may be further developed for application to established human and veterinary vaccines and emphasizes the continuing need for co-ordination and harmonization. It also gives recommendations for work to be undertaken in order to encourage acceptance and implementation of the consistency approach.

  5. QCD Factorization Approach to Cold Nuclear Matter Effects

    Science.gov (United States)

    Qiu, Jianwe

    2016-09-01

    Cold nuclear matter effects exist in all high energy collisions involving identified nucleus (or nuclei). They have been manifested in very significant ways in e-A and p-A, as well as A-A collisions, where the cold nuclear effect is a part of the initial condition which plays a critical role in determining the outcome of heavy ion collisions. In this talk, I will discuss if it is possible to consistently calculate or extract the cold nuclear effect, the advantage and limitation of QCD factorization approach, and the predictive power or the testability of the QCD calculations.

  6. Performance of non-conventional factorization approaches for neutron kinetics

    Energy Technology Data Exchange (ETDEWEB)

    Bulla, S.; Nervo, M. [Politecnico di Torino, Dipartimento Energia, Corso Duca degli Abruzzi, 24, 10129 Torino (Italy)

    2013-07-01

    The use of factorization techniques provides a interesting option for the simulation of the time-dependent behavior of nuclear systems with a reduced computational effort. While point kinetics neglects all spatial and spectral effects, quasi-statics and multipoint kinetics allow to produce results with a higher accuracy for transients involving relevant modifications of the neutron distribution. However, in some conditions these methods can not work efficiently. In this paper, we discuss some possible alternative formulations for the factorization process for neutron kinetics, leading to mathematical models of reduced complications that can allow an accurate simulation of transients involving spatial and spectral effects. The performance of these innovative approaches are compared to standard techniques for some test cases, showing the benefits and shortcomings of the method proposed. (authors)

  7. Quality assurance and benchmarking: an approach for European dental schools.

    Science.gov (United States)

    Jones, M L; Hobson, R S; Plasschaert, A J M; Gundersen, S; Dummer, P; Roger-Leroi, V; Sidlauskas, A; Hamlin, J

    2007-08-01

    This document was written by Task Force 3 of DentEd III, which is a European Union funded Thematic Network working under the auspices of the Association for Dental Education in Europe (ADEE). It provides a guide to assist in the harmonisation of Dental Education Quality Assurance (QA) systems across the European Higher Education Area (EHEA). There is reference to the work, thus far, of DentEd, DentEd Evolves, DentEd III and the ADEE as they strive to assist the convergence of standards in dental education; obviously QA and benchmarking has an important part to play in the European HE response to the Bologna Process. Definitions of Quality, Quality Assurance, Quality Management and Quality Improvement are given and put into the context of dental education. The possible process and framework for Quality Assurance are outlined and some basic guidelines/recommendations suggested. It is recognised that Quality Assurance in Dental Schools has to co-exist as part of established Quality Assurance systems within faculties and universities, and that Schools also may have to comply with existing local or national systems. Perhaps of greatest importance are the 14 'requirements' for the Quality Assurance of Dental Education in Europe. These, together with the document and its appendices, were unanimously supported by the ADEE at its General Assembly in 2006. As there must be more than one road to achieve a convergence or harmonisation standard, a number of appendices are made available on the ADEE website. These provide a series of 'toolkits' from which schools can 'pick and choose' to assist them in developing QA systems appropriate to their own environment. Validated contributions and examples continue to be most welcome from all members of the European dental community for inclusion at this website. It is realised that not all schools will be able to achieve all of these requirements immediately, by definition, successful harmonisation is a process that will take time. At

  8. A high-quality factor hybrid plasmonic nanocavity based on distributed Bragg reflectors

    Science.gov (United States)

    Tu, Linlin; Zhang, Chi; Huang, Zhong; Yau, Jason; Zhan, Peng; Wang, Zhenlin

    2016-09-01

    Herein, we propose a high-quality (Q) factor hybrid plasmonic nanocavity based on distributed Bragg reflectors (DBRs) with low propagation loss and extremely strong mode confinement. This hybrid plasmonic nanocavity is composed of a high-index cylindrical nanowire separated from a metal surface possessing shallow DBRs gratings by a sufficiently thin low-index dielectric layer. The hybrid plasmonic nanocavity possesses advantages such as a high Purcell factor (Fp) of up to nearly 20000 and a gain threshold approaching 266 cm-1 at 1550 nm, promising a greater potential in deep sub-wavelength lasing applications. Project supported by the National Key Basic Research Special Foundation of China (Grant Nos. 2012CB921501 and 2013CB632703) and the National Natural Science Foundation of China (Grant Nos. 11274160, 91221206, and 51271092).

  9. Quality Management in the New Product Development: a PPAP Approach

    Directory of Open Access Journals (Sweden)

    Johanna Hermans

    2013-12-01

    Full Text Available The purpose of this paper is to test Production Part Approval Process (PPAP as a tool to build quality into the new product and processes and ensure that it meets the customer expectations. Research method is qualitative method using so called case-study to study the suitability of PPAP as a tool for quality management by building quality right into the new product and process. The case studies have been made with three different kinds of companies. PPAP is suitable tool for quality management in NPD processes when taking into account many requirements about personnel, processes, documentation etc. The paper has some limitations such as limited sample size. The results are encouraging managers to use PPAP as a tool for managing their company’s product development processes, quality work and supply chain partnerships. The manner in which the stakeholders could use to facilitate a sense of partnerships or co-workers aiming the same goals rather than have a traditional customer-seller relationship was valued in this study.

  10. Image quality assessment using the dead leaves target: experience with the latest approach and further investigations

    Science.gov (United States)

    Artmann, Uwe

    2015-02-01

    The so-called texture loss is a critical parameter in the objective image quality assessment of todays cameras. Especially cameras build in mobile phones show significant loss of low contrast, fine details which are hard to describe using standard resolution measurement procedures. The combination of very small form factor and high pixel count leads to a high demand of noise reduction in the signal-processing pipeline of these cameras. Different work groups within ISO and IEEE are investigating methods to describe the texture loss with an objective method. The so-called dead leaves pattern has been used for quite a while in this context. Image Engineering presented a new intrinsic approach at the Electronic Imaging Conference 2014, which promises to solve the open issue of the original approach, which could be influenced by noise and artifacts. In this paper, we present our experience with the new approach for a large set of different imaging devices. We show, that some sharpening algorithm found in todays cameras can significantly influence the Spatial Frequency Response based on the Dead Leaves structure (SFRDeadLeaves) results and therefore make an objective evaluation of the perceived image quality even harder. For an objective comparison of cameras, the resulting SFR needs to be reduced to a small set of numbers, ideally a single number. The observed sharpening algorithms lead to much better numerical results, while the image quality already degrades due to strong sharpening. So the measured, high SFRDeadLeaves result is not wrong, as it reflects the artificially enhanced SFR, but the numerical result cannot be used as the only number to describe the image quality. We propose to combine the SFRDeadLeaves measurement with other SFR measurement procedures as described in ISO12233:2014. Based on the three different SFR functions using the dead leaves pattern, sinusoidal Siemens Stars and slanted edges, it is possible to obtain a much better description if the

  11. Site-specific water quality guidelines: 1. Derivation approaches based on physicochemical, ecotoxicological and ecological data.

    Science.gov (United States)

    van Dam, R A; Humphrey, C L; Harford, A J; Sinclair, A; Jones, D R; Davies, S; Storey, A W

    2014-01-01

    Generic water quality guidelines (WQGs) are developed by countries/regions as broad scale tools to assist with the protection of aquatic ecosystems from the impacts of toxicants. However, since generic WQGs cannot adequately account for the many environmental factors that may affect toxicity at a particular site, site-specific WQGs are often needed, especially for high environmental value ecosystems. The Australian and New Zealand Guidelines for Fresh and Marine Water Quality provide comprehensive guidance on methods for refining or deriving WQGs for site-specific purposes. This paper describes three such methods for deriving site-specific WQGs, namely: (1) using local reference water quality data, (2) using biological effects data from laboratory-based toxicity testing, and (3) using biological effects data from field surveys. Two case studies related to the assessment of impacts arising from mining operations in northern Australia are used to illustrate the application of these methods. Finally, the potential of several emerging methods designed to assess thresholds of ecological change from field data for deriving site-specific WQGs is discussed. Ideally, multiple lines of evidence approaches, integrating both laboratory and field data, are recommended for deriving site-specific WQGs.

  12. A sensometric approach to cod-quality measurement

    DEFF Research Database (Denmark)

    Jensen, H.S.; Jørgensen, Bo

    1997-01-01

    The quality index method was used for describing the sensory quality of thawed whole cod and raw fillet and the quality of boiled fillet was assessed by profiling analysis. These data were compared to the water holding capacity of the minced cod by principal component analysis (PCA) and partial...... least squares regression. The sensory data and the water holding capacity were correlated to an extent that made possible the prediction of high and low values of water holding capacity. Multivariate methods were also used for extracting some information about the assessor variability. This was done...... by determining the ability of the assessors to predict the water holding capacity through partial least squares regression and by examining the distances between PCA-models of profiling data from the single assessors. (C) 1997 Elsevier Science Ltd. All rights reserved....

  13. An Approach to Establishing International Quality Standards for Medical Travel.

    Science.gov (United States)

    Kácha, Ondřej; Kovács, Beáta E; McCarthy, Cormac; Schuurmans, Angela A T; Dobyns, Christopher; Haller, Elisa; Hinrichs, Saba; Ruggeri, Kai

    2016-01-01

    The number of individuals traveling abroad is increasing annually. The rising popularity of medical travel and the absence of clear minimum quality requirements in this area urgently call for the development of international standards to ensure good practice and patient safety. The aim of this study is to identify the key domains in medical travel where quality standards should be established. Drawing from the evidence-based OECD framework and an extensive literature review, this study proposes three critical areas for consideration: minimum standards of health-care facilities and third-party agencies, financial responsibility, and patient centeredness. Several cultural challenges have been introduced that may pose a barrier to development of the guidelines and should be taken into consideration. Establishing international quality standards in medical travel enhances benefits to patients and providers, which is an urgent necessity given the rapid growth in this industry.

  14. Relationship between the Water Body Chlorophyll-a and Water Quality Factors of Wetlands Baiguishan Reservoir

    Institute of Scientific and Technical Information of China (English)

    SHE Oiu-sheng; TIAN Xun; WANG Guo-zhen; JI Xiao-cun; LI Jiu-xuan; ZHAO Zhen

    2011-01-01

    [ Objective] The aim was to explore the relationship between water body Chlorophyll-a and water quality factors of wetlands Baiguishan reservoir. [ Method] Chlorophyll-a and water quality factors of water quality of Wetlands BaiGuishan Reservoir was studied, the analysis of the relationship on water quality of Wetlands Baiguishan Reservoir was made by use of trophic status indices and SPSS17.0 statistical analysis.[ Result] Total phosphorus was an irnportant factor of influence Chlorophyll-a in reservoir, water body had slight eutrophication phenomenon in reservoir of July to October in 2010. [ Conclusion] Comprehensive management should be strengthened so as to improve the water quality of Baiguishan wetland.

  15. Methodical Approach to Assessment of Quality of Labour Life of Industrial Employees Using Example of Engineering Enterprises

    Directory of Open Access Journals (Sweden)

    Stamatin Oleksandr V.

    2014-03-01

    Full Text Available The goal of the article is presentation of results of study of factors of influence upon quality of labour life of industrial employees and justification of a scorecard of its assessment at the micro-economic level with the use of statistical methods of study. The article proves that the quality of labour life is based on enterprise capabilities, which depend on economic results, identified by the use of financial, material and human resources, effectiveness of the innovation and investment activity. The article reveals main factors that influence the quality of labour life of industrial employees using example of engineering enterprises: labour remuneration, social provisions, possibility to develop personnel, progressive state of fixed assets, financial sustainability of the enterprise, and effectiveness of investing into innovation activity. The article proves expediency of use of statistical methods of study for assessment of quality of labour life of employees, namely: multi-dimensional factor analysis, neural networks and folded additive technique. Their use helped to reveal indicators that are the most sensitive to managerial impact for ensuring quality of labour life. The article justifies stages of methodical approach to assessment of the quality of labour life of industrial employees, which was applied at engineering enterprises, which proves its significance and theoretical substantiation.

  16. A simple parameterization for quality factor as a function of linear energy transfer

    Science.gov (United States)

    Townsend, Lawrence W.; Wilson, John; Cucinotta, Francis A.

    1987-01-01

    The paper presents a simple analytic approximation of the radiation quality factor (Q) as a function of linear energy transfer for use in radiation protection calculations. The paper also presents estimated quality factors in water for protons over a broad range of incident energies. It is shown that the quality factors are less than unity for all proton energies greater than 13 MeV.

  17. Reviewing Impact Factor to Evaluate the Quality of Journals

    Directory of Open Access Journals (Sweden)

    Laleh Samadi

    2011-10-01

    Full Text Available Impact Factor is one of the most important tools to evaluate journals in ISI. In this article, have been tried to extract factors increase the journals' impact factor via studying the literatures and also introduce the factors that may be effective in reducing the weaknesses. The effect of factors such as interval, national, and individual motivations to increase the impact factor of journals and also issues that should be considered when calculating the impact factor, comprised some of the contents of this paper. At the end of the study, in order to evaluate the effect of using the optimal impact factor of journals, some recommendations were presented.

  18. Assessing quality in European educational research indicators and approaches

    CERN Document Server

    Åström, Fredrik; Hansen, Antje

    2014-01-01

    Competition-based models for research policy and management have an increasing influence throughout the research process, from attracting funding to publishing results. The introduction of quality control methods utilizing various forms of performance indicators is part of this development. The authors presented in this volume deal with the following questions: What counts as ‘quality’ and how can this be assessed? What are the possible side effects of current quality control systems on research conducted in the European Research Area, especially in the social sciences and the humanities?

  19. Leadership quality: a factor important for social capital in healthcare organizations.

    Science.gov (United States)

    Strömgren, Marcus; Eriksson, Andrea; Ahlstrom, Linda; Bergman, David Kristofer; Dellve, Lotta

    2017-04-10

    Purpose The purpose of this paper is to investigate the relation between leadership and social capital and what qualities of leadership are important for social capital among employees in hospital settings over time. Design/methodology/approach A cohort of employees in hospitals answered a questionnaire at three occasions. Five small (approx. 100-bed) or mid-sized (approx. 500-bed) hospitals were included. The response rate was 54 percent at baseline ( n=865), 59 percent at one-year follow-up ( n=908) and 67 percent at two-year follow-up ( n=632). Findings Repeated measures over time showed differences between groups in levels of social capital with respect to levels of leadership quality. Relation-oriented leadership had the strongest association with social capital. There was evidence that leadership was associated with social capital over time and that different kinds of leadership qualities were associated with social capital. Research limitations/implications This study conducted and analyzed quantitative data, and therefore, there is no knowledge of managers' or employees' own perceptions in this study. However, it would be interesting to compare managers' decreased and increased leadership quality and how such differences affect social capital over time. Practical implications The findings feature the possibility for healthcare leaders to build high quality leadership as an important resource for social capital, by using different leadership orientations under different circumstances. Originality/value The paper showed that leadership was an important factor for building social capital and that different leadership qualities have different importance with respect to certain circumstances.

  20. Measuring Afterschool Program Quality Using Setting-Level Observational Approaches

    Science.gov (United States)

    Oh, Yoonkyung; Osgood, D. Wayne; Smith, Emilie P.

    2015-01-01

    The importance of afterschool hours for youth development is widely acknowledged, and afterschool settings have recently received increasing attention as an important venue for youth interventions, bringing a growing need for reliable and valid measures of afterschool quality. This study examined the extent to which the two observational tools,…

  1. A tiered analytical approach for investigating poor quality emergency contraceptives.

    Science.gov (United States)

    Monge, María Eugenia; Dwivedi, Prabha; Zhou, Manshui; Payne, Michael; Harris, Chris; House, Blaine; Juggins, Yvonne; Cizmarik, Peter; Newton, Paul N; Fernández, Facundo M; Jenkins, David

    2014-01-01

    Reproductive health has been deleteriously affected by poor quality medicines. Emergency contraceptive pills (ECPs) are an important birth control method that women can use after unprotected coitus for reducing the risk of pregnancy. In response to the detection of poor quality ECPs commercially available in the Peruvian market we developed a tiered multi-platform analytical strategy. In a survey to assess ECP medicine quality in Peru, 7 out of 25 different batches showed inadequate release of levonorgestrel by dissolution testing or improper amounts of active ingredient. One batch was found to contain a wrong active ingredient, with no detectable levonorgestrel. By combining ultrahigh performance liquid chromatography-ion mobility spectrometry-mass spectrometry (UHPLC-IMS-MS) and direct analysis in real time MS (DART-MS) the unknown compound was identified as the antibiotic sulfamethoxazole. Quantitation by UHPLC-triple quadrupole tandem MS (QqQ-MS/MS) indicated that the wrong ingredient was present in the ECP sample at levels which could have significant physiological effects. Further chemical characterization of the poor quality ECP samples included the identification of the excipients by 2D Diffusion-Ordered Nuclear Magnetic Resonance Spectroscopy (DOSY 1H NMR) indicating the presence of lactose and magnesium stearate.

  2. A tiered analytical approach for investigating poor quality emergency contraceptives.

    Directory of Open Access Journals (Sweden)

    María Eugenia Monge

    Full Text Available Reproductive health has been deleteriously affected by poor quality medicines. Emergency contraceptive pills (ECPs are an important birth control method that women can use after unprotected coitus for reducing the risk of pregnancy. In response to the detection of poor quality ECPs commercially available in the Peruvian market we developed a tiered multi-platform analytical strategy. In a survey to assess ECP medicine quality in Peru, 7 out of 25 different batches showed inadequate release of levonorgestrel by dissolution testing or improper amounts of active ingredient. One batch was found to contain a wrong active ingredient, with no detectable levonorgestrel. By combining ultrahigh performance liquid chromatography-ion mobility spectrometry-mass spectrometry (UHPLC-IMS-MS and direct analysis in real time MS (DART-MS the unknown compound was identified as the antibiotic sulfamethoxazole. Quantitation by UHPLC-triple quadrupole tandem MS (QqQ-MS/MS indicated that the wrong ingredient was present in the ECP sample at levels which could have significant physiological effects. Further chemical characterization of the poor quality ECP samples included the identification of the excipients by 2D Diffusion-Ordered Nuclear Magnetic Resonance Spectroscopy (DOSY 1H NMR indicating the presence of lactose and magnesium stearate.

  3. Quality assurance and benchmarking : An approach for European dental schools

    NARCIS (Netherlands)

    Jones, M. L.; Hobson, R. S.; Plasschaert, A. J. M.; Gundersen, S.; Dummer, P.; Roger-Leroi, V.; Sidlauskas, A.; Hamlin, J.

    2007-01-01

    This document was written by Task Force 3 of DentEd III, which is a European Union funded Thematic Network working under the auspices of the Association for Dental Education in Europe (ADEE). It provides a guide to assist in the harmonisation of Dental Education Quality Assurance (QA) systems across

  4. Quality assurance and benchmarking: an approach for European dental schools.

    NARCIS (Netherlands)

    Jones, M.L.; Hobson, R.S.; Plasschaert, A.J.M.; Gundersen, S.; Dummer, P.; Roger-Leroi, V.; Sidlauskas, A.; Hamlin, J.

    2007-01-01

    This document was written by Task Force 3 of DentEd III, which is a European Union funded Thematic Network working under the auspices of the Association for Dental Education in Europe (ADEE). It provides a guide to assist in the harmonisation of Dental Education Quality Assurance (QA) systems across

  5. Quality assurance and benchmarking : An approach for European dental schools

    NARCIS (Netherlands)

    Jones, M. L.; Hobson, R. S.; Plasschaert, A. J. M.; Gundersen, S.; Dummer, P.; Roger-Leroi, V.; Sidlauskas, A.; Hamlin, J.

    This document was written by Task Force 3 of DentEd III, which is a European Union funded Thematic Network working under the auspices of the Association for Dental Education in Europe (ADEE). It provides a guide to assist in the harmonisation of Dental Education Quality Assurance (QA) systems across

  6. STRATEGIC APPROACH TO QUALITY MANAGEMENT ENTERPRISES MARKETING ACTIVITIES

    OpenAIRE

    DATSII NADIIA VASYLIVNA

    2017-01-01

    The conceptual model of quality strategic management of marketing activities includes the following elements: strategic architecture, strategic organization, strategic audit, each is considered in terms of information, functional, methodological, organizational and economic aspects. The implementation of this model will enhance the effectiveness of strategic management of enterprise marketing activities and ensure their long-term competitiveness.Conceptual-categorical apparatus is supplemente...

  7. Quality assurance and benchmarking : An approach for European dental schools

    NARCIS (Netherlands)

    Jones, M. L.; Hobson, R. S.; Plasschaert, A. J. M.; Gundersen, S.; Dummer, P.; Roger-Leroi, V.; Sidlauskas, A.; Hamlin, J.

    2007-01-01

    This document was written by Task Force 3 of DentEd III, which is a European Union funded Thematic Network working under the auspices of the Association for Dental Education in Europe (ADEE). It provides a guide to assist in the harmonisation of Dental Education Quality Assurance (QA) systems across

  8. Quality assurance and benchmarking: an approach for European dental schools.

    NARCIS (Netherlands)

    Jones, M.L.; Hobson, R.S.; Plasschaert, A.J.M.; Gundersen, S.; Dummer, P.; Roger-Leroi, V.; Sidlauskas, A.; Hamlin, J.

    2007-01-01

    This document was written by Task Force 3 of DentEd III, which is a European Union funded Thematic Network working under the auspices of the Association for Dental Education in Europe (ADEE). It provides a guide to assist in the harmonisation of Dental Education Quality Assurance (QA) systems across

  9. Think Quality! The Deming Approach Does Work in Libraries.

    Science.gov (United States)

    Mackey, Terry; Mackey, Kitty

    1992-01-01

    Presents W. Edwards Deming's Total Quality Management method and advocates its adoption in libraries. The 14 points that form the basis of Deming's philosophy are discussed in the context of the library setting. A flow chart of the reference process and user survey questions are included. (MES)

  10. Factors influencing crime rates: an econometric analysis approach

    Science.gov (United States)

    Bothos, John M. A.; Thomopoulos, Stelios C. A.

    2016-05-01

    The scope of the present study is to research the dynamics that determine the commission of crimes in the US society. Our study is part of a model we are developing to understand urban crime dynamics and to enhance citizens' "perception of security" in large urban environments. The main targets of our research are to highlight dependence of crime rates on certain social and economic factors and basic elements of state anticrime policies. In conducting our research, we use as guides previous relevant studies on crime dependence, that have been performed with similar quantitative analyses in mind, regarding the dependence of crime on certain social and economic factors using statistics and econometric modelling. Our first approach consists of conceptual state space dynamic cross-sectional econometric models that incorporate a feedback loop that describes crime as a feedback process. In order to define dynamically the model variables, we use statistical analysis on crime records and on records about social and economic conditions and policing characteristics (like police force and policing results - crime arrests), to determine their influence as independent variables on crime, as the dependent variable of our model. The econometric models we apply in this first approach are an exponential log linear model and a logit model. In a second approach, we try to study the evolvement of violent crime through time in the US, independently as an autonomous social phenomenon, using autoregressive and moving average time-series econometric models. Our findings show that there are certain social and economic characteristics that affect the formation of crime rates in the US, either positively or negatively. Furthermore, the results of our time-series econometric modelling show that violent crime, viewed solely and independently as a social phenomenon, correlates with previous years crime rates and depends on the social and economic environment's conditions during previous years.

  11. WHAT FACTORS INFLUENCE QUALITY SERVICE IMPROVEMENT IN MONTENEGRO: EMPIRICAL ANALYSIS

    Directory of Open Access Journals (Sweden)

    Djurdjica Perovic

    2013-03-01

    Full Text Available In this paper, using an Ordinary Least Square regression (OLS, we investigate whether intangible elements influence tourist's perception about service quality. Our empirical results based on tourist survey in Montenegro, indicate that intangible elements of tourism product have positive impact on tourist's overall perception of service quality in Montenegro.

  12. Factors Influencing Perceptions of Service Quality in Cooperative Extension Workers

    Science.gov (United States)

    Anaza, Nwamaka A.; Rutherford, Brian N.; Widdows, Richard

    2012-01-01

    The authors examined the direct and indirect impact of empowerment on service quality as perceived by Extension staff. Using a sample 283 respondents, the results revealed that along with empowerment, constructs such as job satisfaction and organizational identification positively affected service quality. Undoubtedly, each of these variables…

  13. The Impact Factor: Implications of Open Access on Quality

    Science.gov (United States)

    Grozanick, Sara E.

    2010-01-01

    There has been debate about the extent to which open access affects the quality of scholarly work. At the same time, researchers have begun to look for ways to evaluate the quality of open access publications. Dating back to the growth of citation indexes during the 1960s and 1970s, citation analysis--examining citation statistics--has since been…

  14. The Impact Factor: Implications of Open Access on Quality

    Science.gov (United States)

    Grozanick, Sara E.

    2010-01-01

    There has been debate about the extent to which open access affects the quality of scholarly work. At the same time, researchers have begun to look for ways to evaluate the quality of open access publications. Dating back to the growth of citation indexes during the 1960s and 1970s, citation analysis--examining citation statistics--has since been…

  15. Factors Influencing Perceptions of Service Quality in Cooperative Extension Workers

    Science.gov (United States)

    Anaza, Nwamaka A.; Rutherford, Brian N.; Widdows, Richard

    2012-01-01

    The authors examined the direct and indirect impact of empowerment on service quality as perceived by Extension staff. Using a sample 283 respondents, the results revealed that along with empowerment, constructs such as job satisfaction and organizational identification positively affected service quality. Undoubtedly, each of these variables…

  16. Factors Determinants the Choice of Mobile Service Providers: Structural Equation Modeling Approach on Bangladeshi Consumers

    Directory of Open Access Journals (Sweden)

    Ahasanul Haque

    2010-07-01

    Full Text Available The aim of this study is to find out what were the factors that may have played significant role to select the telecommunication service providers. In general this research has an intention to develop a research framework grounded on a strong theoretical and literature review background. The survey instruments employed on Bangladeshi consumers included demographic background, price, service quality, product quality and availability and promotional offers for consumer perception. Thus the structural equation modeling approach was necessary in order to examine the variables. The data analysis was conducted using SPSS and AMOS (Analysis of Moment Structure with the software package for windows. From the result it is revealed that paths are related to the casual processes significantly. Among all the significant variables, from our result, Price is the most important among our respondents followed by Service quality, product quality and promotion. Further research should be considered to gather more information regarding the service quality and customers’ satisfaction dimensions in context of the Bangladeshi mobile phone operators. It is hoped that the findings of this study may assist mobile phone industry in Bangladesh about their services and promotion of their services. However, the findings of this study may provide needed feedback and contribute to the improvement of players’ strategy and their marketing program

  17. Modern psychometric approaches to analysis of scales for health-related quality of life

    DEFF Research Database (Denmark)

    Bjorner, Jakob Bue; Bech, Per

    2016-01-01

    In recent years, much effort has been invested in the development of new instruments for assessment of health-related quality of life (HRQOL). For many new instruments, modern psychometric methods, such as item response theory (IRT) models, have been used, either as supplemental to classical...... psychometric testing or as the primary methodological approach. We will use the term modern psychometric methods to refer to psychometric methods for multi-item scales that (1) examine the contribution of each item to the measurement properties of the overall scale and (2) recognize that items are categorical....... The models include Rasch models (Rasch 1980; Fischer and Molenaar 1995), other IRT models (Samejima 1969; van der Linden and Hambleton 1997), and factor analytic models for categorical data (Muthén 1984). “Modern” psychometric methods have actually a rather long history within psychiatric research (both...

  18. A quality by design approach to investigate the effect of mannitol and dicalcium phosphate qualities on roll compaction.

    Science.gov (United States)

    Souihi, Nabil; Dumarey, Melanie; Wikström, Håkan; Tajarobi, Pirjo; Fransson, Magnus; Svensson, Olof; Josefson, Mats; Trygg, Johan

    2013-04-15

    Roll compaction is a continuous process for solid dosage form manufacturing increasingly popular within pharmaceutical industry. Although roll compaction has become an established technique for dry granulation, the influence of material properties is still not fully understood. In this study, a quality by design (QbD) approach was utilized, not only to understand the influence of different qualities of mannitol and dicalcium phosphate (DCP), but also to predict critical quality attributes of the drug product based solely on the material properties of that filler. By describing each filler quality in terms of several representative physical properties, orthogonal projections to latent structures (OPLS) was used to understand and predict how those properties affected drug product intermediates as well as critical quality attributes of the final drug product. These models were then validated by predicting product attributes for filler qualities not used in the model construction. The results of this study confirmed that the tensile strength reduction, known to affect plastic materials when roll compacted, is not prominent when using brittle materials. Some qualities of these fillers actually demonstrated improved compactability following roll compaction. While direct compression qualities are frequently used for roll compacted drug products because of their excellent flowability and good compaction properties, this study revealed that granules from these qualities were more poor flowing than the corresponding powder blends, which was not seen for granules from traditional qualities. The QbD approach used in this study could be extended beyond fillers. Thus any new compound/ingredient would first be characterized and then suitable formulation characteristics could be determined in silico, without running any additional experiments.

  19. A Study of Evaluation System of Restricting Factors in Training Students' Qualities

    Institute of Scientific and Technical Information of China (English)

    MA Xiao-yan

    2002-01-01

    This paper studies evaluation system of restricting factors in training students' qualities by modern mathematical method of analysis hierarchy process and principal factor analysis, and to build up a mathematical model of evaluation system.

  20. Quality and Competitiveness: A Lean Six Sigma Approach

    Directory of Open Access Journals (Sweden)

    Irina-Virginia Drăgulănescu

    2015-11-01

    Full Text Available Originally developed to improve the quality and production efficiency, Lean Six Sigma is now widely adopted in other non-manufacturing sectors such as financial, trade, services, etc. The methodology known as Lean Six Sigma combines the Six Sigma techniques, ‒ which allow companies to reduce manufacturing defects ‒ and the Lean Manufacturing principles, ‒ which help companies benefit from faster processing for lower costs and with superior quality. As a result of the research, the authors observed that, despite growing popularity and impressive outcomes obtained by some companies, the Lean Six Sigma model does not always offer the expected results. However, the research has shown that the analysed company, operating in the field of courier services has managed to boost productivity and competitiveness by implementing measures that generated added value.

  1. Approaches to verification of two-dimensional water quality models

    Energy Technology Data Exchange (ETDEWEB)

    Butkus, S.R. (Tennessee Valley Authority, Chattanooga, TN (USA). Water Quality Dept.)

    1990-11-01

    The verification of a water quality model is the one procedure most needed by decision making evaluating a model predictions, but is often not adequate or done at all. The results of a properly conducted verification provide the decision makers with an estimate of the uncertainty associated with model predictions. Several statistical tests are available for quantifying of the performance of a model. Six methods of verification were evaluated using an application of the BETTER two-dimensional water quality model for Chickamauga reservoir. Model predictions for ten state variables were compared to observed conditions from 1989. Spatial distributions of the verification measures showed the model predictions were generally adequate, except at a few specific locations in the reservoir. The most useful statistics were the mean standard error of the residuals. Quantifiable measures of model performance should be calculated during calibration and verification of future applications of the BETTER model. 25 refs., 5 figs., 7 tabs.

  2. Quality improvement in basic histotechnology: the lean approach.

    Science.gov (United States)

    Clark, David

    2016-01-01

    Lean is a comprehensive system of management based on the Toyota production system (TPS), encompassing all the activities of an organization. It focuses management activity on creating value for the end-user by continuously improving operational effectiveness and removing waste. Lean management creates a culture of continuous quality improvement with a strong emphasis on developing the problem-solving capability of staff using the scientific method (Deming's Plan, Do, Check, Act cycle). Lean management systems have been adopted by a number of histopathology departments throughout the world to simultaneously improve quality (reducing errors and shortening turnround times) and lower costs (by increasing efficiency). This article describes the key concepts that make up a lean management system, and how these concepts have been adapted from manufacturing industry and applied to histopathology using a case study of lean implementation and evidence from the literature. It discusses the benefits, limitations, and pitfalls encountered when implementing lean management systems.

  3. A stochastic physical system approach to modeling river water quality

    Science.gov (United States)

    Curi, W. F.; Unny, T. E.; Kay, J. J.

    1995-06-01

    In this paper, concepts of network thermodynamics are applied to a river water quality model, which is based on Streeter-Phelps equations, to identify the corresponding physical components and their topology. Then, the randomness in the parameters, input coefficients and initial conditions are modeled by Gaussian white noises. From the stochastic components of the physical system description of problem and concepts of physical system theory, a set of stochastic differential equations can be automatically generated in a computer and the recent developments on the automatic formulation of the moment equations based on Ito calculus can be used. This procedure is illustrated through the solution of an example of stochastic river water quality problem and it is also shown how other related problems with different configurations can be automatically solved in a computer using just one software.

  4. Factors Affecting the Quality and Quantity of Sleep in Coronary Artery Bypass Graft Patients

    Directory of Open Access Journals (Sweden)

    H Esmaily

    2008-10-01

    Full Text Available Introduction: Sleep disturbance is common in patients undergoing Coronary Artery Bypass Graft surgery and has been recognized for more than 30 years. New literature suggests the importance of sleep and rest for restoration, protection and promotion of function and wellbeing of these patients. Because of the importance of the role of nurses in diagnosis and treatment of sleep disorders, this study was conducted to determine possible effective factors on sleep quality and sleep quantity of patients after CABG. Methods: This longitudinal, descriptive and correlational study was conducted on 91 patients admitted to Imam Reza Hospital in Mashad City in 2005-2006. Subjects were selected according to inclusion and exclusion criteria. Data was collected by interview in three stages: 24 hours before surgery, as well as 6 weeks and 10 weeks after surgery. Subjective sleep quality was measured with PSQI and sleep quantity was measured with sleep log. The first two interviews were done at the hospital clinic and the last via telephone. Data was analyzed in SPSS using student T test, Pearson correlation coefficient and General Linear Model. Results: According to Univariable analysis, variables such as age (p=0.03, aorta clamp time (p=0.003, mechanical ventilation time (p=0.01, staying time in hospital (p=0.04 can affect sleep quantity 10 weeks after surgery. Previous history of sleep disorder (p=0.005, diabetes (p=0.02, use of diuretic drugs before surgery (p=0.04 and ACEI drugs after surgery (p=0.01 can affect sleep quality 10 weeks after surgery. Conclusion: Sleep disorder history (p=0.01, use of diuretic drugs before surgery (p=0.04 and sleep quantity 6 weeks after surgery (p=0.01 have been the most effective factors on sleep quality 10 weeks after surgery, whereas quality of life 10 weeks after surgery (p=0.04 has been the most effective factor on sleep quantity 10 weeks after surgery. There is therefore a necessity for presenting approaches in order to

  5. Megacities, air quality and climate: Seamless prediction approach

    Science.gov (United States)

    Baklanov, Alexander; Molina, Luisa T.; Gauss, Michael

    2016-04-01

    The rapid urbanization and growing number of megacities and urban complexes requires new types of research and services that make best use of science and available technology. With an increasing number of humans now living in urban sprawls, there are urgent needs of examining what the rising number of megacities means for air pollution, local climate and the effects these changes have on global climate. Such integrated studies and services should assist cities in facing hazards such as storm surge, flooding, heat waves, and air pollution episodes, especially in changing climates. While important advances have been made, new interdisciplinary research studies are needed to increase our understanding of the interactions between emissions, air quality, and regional and global climates. Studies need to address both basic and applied research and bridge the spatial and temporal scales connecting local emissions and air pollution and local weather, global atmospheric chemistry and climate. This paper reviews the current status of studies of the complex interactions between climate, air quality and megacities, and identifies the main gaps in our current knowledge as well as further research needs in this important field of research. Highlights • Climate, air quality and megacities interactions: gaps in knowledge, research needs. • Urban hazards: pollution episodes, storm surge, flooding, heat waves, public health. • Global climate change affects megacities' climate, environment and comfort. • Growing urbanization requires integrated weather, environment and climate monitoring systems. • New generation of multi-scale models and seamless integrated urban services are needed. Reference Baklanov, A., L.T. Molina, M. Gauss (2016) Megacities, air quality and climate. Atmospheric Environment, 126: 235-249. doi:10.1016/j.atmosenv.2015.11.059

  6. Pharmaceutical product development: A quality by design approach

    OpenAIRE

    Pramod, Kannissery; Tahir, M. Abu; Charoo, Naseem A.; Ansari, Shahid H.; Ali, Javed

    2016-01-01

    The application of quality by design (QbD) in pharmaceutical product development is now a thrust area for the regulatory authorities and the pharmaceutical industry. International Conference on Harmonization and United States Food and Drug Administration (USFDA) emphasized the principles and applications of QbD in pharmaceutical development in their guidance for the industry. QbD attributes are addressed in question-based review, developed by USFDA for chemistry, manufacturing, and controls s...

  7. Assessing quality in software development: An agile methodology approach

    OpenAIRE

    V. Rodríguez-Hernández; M.C. Espino-Gudiño; J.L. González-Pérez; J. Gudiño-Bazaldúa; Victor Castano

    2015-01-01

    A novel methodology, result of 10 years of in-field testing, which makes possible the convergence of different types of models and quality standards for Engineering and Computer Science Faculties, is presented. Since most software-developing companies are small and medium sized, the projects developed must focuson SCRUM and Extreme Programming (XP), opposed to a RUP, which is quite heavy, as well as on Personal Software Process (PSP) and Team Software Process (TSP), which provide students wit...

  8. Pharmaceutical product development: A quality by design approach

    OpenAIRE

    Pramod, Kannissery; Tahir, M. Abu; Charoo, Naseem A.; Shahid H. Ansari; Ali, Javed

    2016-01-01

    The application of quality by design (QbD) in pharmaceutical product development is now a thrust area for the regulatory authorities and the pharmaceutical industry. International Conference on Harmonization and United States Food and Drug Administration (USFDA) emphasized the principles and applications of QbD in pharmaceutical development in their guidance for the industry. QbD attributes are addressed in question-based review, developed by USFDA for chemistry, manufacturing, and controls s...

  9. The quality analyses of olive cake fuel pellets - mathematical approach

    Directory of Open Access Journals (Sweden)

    Brlek Tea I.

    2016-01-01

    Full Text Available This article investigates the effect of processing parameters (conditioning temperature and binder content, on final quality of produced agro-pellets for heat energy generation, obtained from four different olive cultivars using different technological parameters. Technological, physical and chemical properties of pellets (carbon, hydrogen, nitrogen and sulphur content, particle density, abrasion length, moisture, ash content, higher and lower heating values, fixed carbon and volatile matter content have been determined to assess their quality. The performance of Artificial Neural Network (ANN was compared with the performance of second order polynomial (SOP model, as well as with the obtained experimental data in order to develop rapid and accurate mathematical model for prediction of final quality parameters of agro-pellets. SOP model showed high coefficients of determination (r2, between 0.692 and 0.955, while ANN model showed high prediction accuracy with r2 between 0.544 and 0.994. [Projekat Ministarstva nauke Republike Srbije, br. III 46005 i br. TR-31055

  10. Evaluating Individual Students' Perceptions of Instructional Quality: An Investigation of their Factor Structure, Measurement Invariance, and Relations to Educational Outcomes

    Science.gov (United States)

    Scherer, Ronny; Nilsen, Trude; Jansen, Malte

    2016-01-01

    Students' perceptions of instructional quality are among the most important criteria for evaluating teaching effectiveness. The present study evaluates different latent variable modeling approaches (confirmatory factor analysis, exploratory structural equation modeling, and bifactor modeling), which are used to describe these individual perceptions with respect to their factor structure, measurement invariance, and the relations to selected educational outcomes (achievement, self-concept, and motivation in mathematics). On the basis of the Programme for International Student Assessment (PISA) 2012 large-scale data sets of Australia, Canada, and the USA (N = 26,746 students), we find support for the distinction between three factors of individual students' perceptions and full measurement invariance across countries for all modeling approaches. In this regard, bifactor exploratory structural equation modeling outperformed alternative approaches with respect to model fit. Our findings reveal significant relations to the educational outcomes. This study synthesizes different modeling approaches of individual students' perceptions of instructional quality and provides insights into the nature of these perceptions from an individual differences perspective. Implications for the measurement and modeling of individually perceived instructional quality are discussed. PMID:26903917

  11. Factors influencing quality of life in patients with active tuberculosis

    Directory of Open Access Journals (Sweden)

    Cox Victoria C

    2004-10-01

    Full Text Available Abstract Background With effective treatment strategies, the focus of tuberculosis (TB management has shifted from the prevention of mortality to the avoidance of morbidity. As such, there should be an increased focus on quality of life (QoL experienced by individuals being treated for TB. The objective of our study was to identify areas of QoL that are affected by active TB using focus groups and individual interviews. Methods English, Cantonese, and Punjabi-speaking subjects with active TB who were receiving treatment were eligible for recruitment into the study. Gender-based focus group sessions were conducted for the inner city participants but individual interviews were conducted for those who came to the main TB clinic or were hospitalized. Facilitators used open-ended questions and participants were asked to discuss their experiences of being diagnosed with tuberculosis, what impact it had on their lives, issues around adherence to anti-TB medications and information pertaining to their experience with side effects to these medications. All data were audio-recorded, transcribed verbatim, and analyzed using constant comparative analysis. Results 39 patients with active TB participated. The mean age was 46.2 years (SD 18.4 and 62% were male. Most were Canadian-born being either Caucasian or Aboriginal. Four themes emerged from the focus groups and interviews. The first describes issues related to the diagnosis of tuberculosis and sub-themes were identified as 'symptoms', 'health care provision', and 'emotional impact'. The second theme discusses TB medication factors and the sub-themes identified were 'adverse effects', 'ease of administration', and 'adherence'. The third theme describes social support and functioning issues for the individuals with TB. The fourth theme describes health behavior issues for the individuals with TB and the identified sub-themes were "behavior modification" and "TB knowledge." Conclusion Despite the ability to

  12. Identifying perinatal risk factors for infant maltreatment: an ecological approach

    Directory of Open Access Journals (Sweden)

    Hallisey Elaine J

    2006-12-01

    Full Text Available Abstract Background Child maltreatment and its consequences are a persistent problem throughout the world. Public health workers, human services officials, and others are interested in new and efficient ways to determine which geographic areas to target for intervention programs and resources. To improve assessment efforts, selected perinatal factors were examined, both individually and in various combinations, to determine if they are associated with increased risk of infant maltreatment. State of Georgia birth records and abuse and neglect data were analyzed using an area-based, ecological approach with the census tract as a surrogate for the community. Cartographic visualization suggested some correlation exists between risk factors and child maltreatment, so bivariate and multivariate regression were performed. The presence of spatial autocorrelation precluded the use of traditional ordinary least squares regression, therefore a spatial regression model coupled with maximum likelihood estimation was employed. Results Results indicate that all individual factors or their combinations are significantly associated with increased risk of infant maltreatment. The set of perinatal risk factors that best predicts infant maltreatment rates are: mother smoked during pregnancy, families with three or more siblings, maternal age less than 20 years, births to unmarried mothers, Medicaid beneficiaries, and inadequate prenatal care. Conclusion This model enables public health to take a proactive stance, to reasonably predict areas where poor outcomes are likely to occur, and to therefore more efficiently allocate resources. U.S. states that routinely collect the variables the National Center for Health Statistics (NCHS defines for birth certificates can easily identify areas that are at high risk for infant maltreatment. The authors recommend that agencies charged with reducing child maltreatment target communities that demonstrate the perinatal risks

  13. Factors impacting on the microbiological quality and safety of ...

    African Journals Online (AJOL)

    hope&shola

    2010-12-06

    Dec 6, 2010 ... 1Department of Food Science and Technology, University of Namibia, P. Bag ... of water for marine fish processing plants, the treatment and the quality of the ..... Compendium of methods for the microbiological examination of.

  14. factors affecting soil quality maintenance in northern katsina state ...

    African Journals Online (AJOL)

    positive and negative changes in soil quality (Andrews, et. al. 2004). Many researchers ... ecosystem boundaries, to sustain plant and animal productiv- ity, maintain or ... of a soil body, within land use, landscape and climate boundaries, to ...

  15. Factors influencing quality decision-making: regulatory and pharmaceutical industry perspectives.

    Science.gov (United States)

    Donelan, Ronan; Walker, Stuart; Salek, Sam

    2015-03-01

    Currently, there is no qualified understanding of the influences, behaviours and other factors that impact the decision-making of individuals and organisations involved in the development of new medicines. The aim of this qualitative study was to investigate and identify the important issues that influence quality decision-making. Semi-structured interviews were carried out with 29 senior decision-makers from the pharmaceutical industry and regulatory authorities. The study participants were invited to discuss and review their perception of decision-making within their organisation, its role in drug development and the regulatory review and their awareness and use of decision-making techniques and the impact and monitoring of decisions. The analyses (using NVivo 8(©) software) resulted in the identification of 32 major and 97 sub-themes that were consolidated into 19 overarching themes. These included items such as quality and validity of data, time considerations, organisational and cultural influences, analytical and logical approach, qualification and experience, subjective and personal considerations, political influences, precedents for similar previous decisions, understanding of the decision in question, impact analyses, audit trail, education and awareness, individual versus corporate decision-making and frameworks. Relationships between themes were identified. The 19 overarching decision-making themes were integrated into a framework for quality decision-making. This study has achieved its aim of exploring decision-making from the perspective of the individual and the organisation working in drug development and the regulatory review and has identified issues and considerations relating to making good quality decisions and allowed for the generation of a framework to aid quality decision-making. Copyright © 2015 John Wiley & Sons, Ltd.

  16. Analysis Supporting Factors and Constraints LPMP Performance in Improving the Quality of Education in Jambi Province

    Science.gov (United States)

    Rosadi, Kemas Imron

    2015-01-01

    Development of education in Indonesia is based on three aspects, namely equity and expansion, quality and relevance, as well as good governance. Quality education is influenced by several factors related to quality education managerial leaders, limited funds, facilities, educational facilities, media, learning resources, tools and training…

  17. Total Quality Management (TQM) in Self-Financed Technical Institutions: A Quality Function Deployment (QFD) and Force Field Analysis Approach

    Science.gov (United States)

    Thakkar, Jitesh; Deshmukh, S. G.; Shastree, Anil

    2006-01-01

    Purpose: To explore the potential for adoption of TQM in self-financed technical institutions in the light of new demands and challenges posed by customers/students and society. Design/methodology/approach: The paper presents use of quality function deployment (QFD) which prioritizes technical requirements and correlates them with various…

  18. Total Quality Management (TQM) in Self-Financed Technical Institutions: A Quality Function Deployment (QFD) and Force Field Analysis Approach

    Science.gov (United States)

    Thakkar, Jitesh; Deshmukh, S. G.; Shastree, Anil

    2006-01-01

    Purpose: To explore the potential for adoption of TQM in self-financed technical institutions in the light of new demands and challenges posed by customers/students and society. Design/methodology/approach: The paper presents use of quality function deployment (QFD) which prioritizes technical requirements and correlates them with various…

  19. Continuous quality improvement in acute health care: creating a holistic and integrated approach.

    Science.gov (United States)

    Sewell, N

    1997-01-01

    Reviews the range of quality activity in a National Health Service hospital trust, using a staff questionnaire survey, self-assessment against the Baldrige Quality Award criteria, and the application of the SERVQUAL approach to service quality assessment. Reviews the acute health care quality programme literature. Finds that there are needs for greater integration of quality effort, to engage with patients in a more meaningful manner, and to achieve greater commitment and involvement from clinicians and managers. Identifies lack of time and resources as a major barrier to greater application of quality programmes. Explores ways of developing a more holistic and integrated programme of quality improvement. Describes the creation and implementation of a model for continuous improvement in health care quality.

  20. Memetic pool as a new approach in service quality analysis

    Directory of Open Access Journals (Sweden)

    Stepaniuk Krzysztof

    2016-12-01

    Full Text Available This paper attempts to decompose, as well as perform a quantitative and qualitative analysis of the way to externalize the perception of the accommodation service. The research material consisted of the opinions of users of accommodation facilities, located in the vicinity of the twelve selected national parks in Poland. It was assumed that the reflection of the perception of the quality of the service process is the transfer of intangible content related to the service itself, which can be externalized, among other things, through entries in social networks.

  1. Performance improvements in longwall mining using a total quality approach

    Energy Technology Data Exchange (ETDEWEB)

    Singh, R.N.; Porter, I.; Vatovec, W.R. [University of Wollongong, Wollongong, NSW (Australia). Dept. of Civil Mining and Environmental Engineering

    1998-06-01

    The paper briefly describes the production and productivity trends in coal mining in Australia. It is considered that the greatest impediment in achieving full potential from a mechanised longwall face in Australia is the lack of reliability of face equipment and inadequate gate roadways development rates resulting in discontinuity of longwall operations. In the quest for increasing roadway development rates, a new generation of development machinery are being increasingly used. Experience has shown that the application of high-tech equipment alone is unable to achieve desired development rates. Application of Total Quality Management Principles is necessary to improve the organisational behaviour of the mine and therefore, the development rates.

  2. Establishing the overall service quality of engineering education: fuzzy logic approach

    Science.gov (United States)

    Shekhar, N. Chandra; Venkatasubbaiah, K.; Kandukuria, N. R.

    2012-12-01

    Measuring overall service quality (OSQ) is gaining prominence in higher education due to the increased competition among engineering education institutions (EEIs) and growing awareness about value for money among the public. Determination of OSQ on certain institutional aspects is done by various agencies throughout the world. Each system uses a different set of weighted indicators to measure the overall service quality of institutions. Five service quality factors, namely professionalism, integrated education, facilities, responsiveness and empathy are considered in the study. Trapezoidal fuzzy numbers are used to determine the aggregate weights of the factors to handle the vagueness present in the linguistic values of the stakeholders' subjective opinions. Final weights of the factors are assessed by taking the distances of each factor between Fuzzy Positive Ideal Rating and Fuzzy Negative Ideal Rating. An illustrative study is presented to determine the OSQ of EEIs. The results help to focus on the factors which need immediate attention to enhance the quality of EEIs.

  3. The human factors of quality and QA in R D environments

    Energy Technology Data Exchange (ETDEWEB)

    Hill, S.G.

    1990-01-01

    Achieving quality is a human activity. It is therefore important to consider the human in the design, development and evaluation of work processes and environments in an effort to enhance human performance and minimize error. It is also important to allow for individual differences when considering human factors issues. Human Factors is the field of study which can provide information on integrating the human into the system. Human factors and quality are related for the customer of R D work, R D personnel who perform the work, and the quality professional who overviews the process of quality in the work. 18 refs., 1 fig.

  4. Quality factor due to roughness scattering of shear horizontal surface acoustic waves in nanoresonators

    NARCIS (Netherlands)

    Palasantzas, G.

    2008-01-01

    In this work we study the quality factor associated with dissipation due to scattering of shear horizontal surface acoustic waves by random self-affine roughness. It is shown that the quality factor is strongly influenced by both the surface roughness exponent H and the roughness amplitude w to late

  5. Development of management quality system for metallurgical enterprise based on Balanced Scorecard with limiting factors

    Directory of Open Access Journals (Sweden)

    Galina Ledneva

    2009-12-01

    Full Text Available The article considers inefficiency of the existing quality management systems (QMS based on standards ISO series 9000. The authors offer integrated QMS with limiting factors on Balanced Scorecard. The Balanced Scorecard with limiting factors helps to efficiently direct process of continuous improvement and achieve top-priority criteria in quality management domain.

  6. A quality risk management model approach for cell therapy manufacturing.

    Science.gov (United States)

    Lopez, Fabio; Di Bartolo, Chiara; Piazza, Tommaso; Passannanti, Antonino; Gerlach, Jörg C; Gridelli, Bruno; Triolo, Fabio

    2010-12-01

    International regulatory authorities view risk management as an essential production need for the development of innovative, somatic cell-based therapies in regenerative medicine. The available risk management guidelines, however, provide little guidance on specific risk analysis approaches and procedures applicable in clinical cell therapy manufacturing. This raises a number of problems. Cell manufacturing is a poorly automated process, prone to operator-introduced variations, and affected by heterogeneity of the processed organs/tissues and lot-dependent variability of reagent (e.g., collagenase) efficiency. In this study, the principal challenges faced in a cell-based product manufacturing context (i.e., high dependence on human intervention and absence of reference standards for acceptable risk levels) are identified and addressed, and a risk management model approach applicable to manufacturing of cells for clinical use is described for the first time. The use of the heuristic and pseudo-quantitative failure mode and effect analysis/failure mode and critical effect analysis risk analysis technique associated with direct estimation of severity, occurrence, and detection is, in this specific context, as effective as, but more efficient than, the analytic hierarchy process. Moreover, a severity/occurrence matrix and Pareto analysis can be successfully adopted to identify priority failure modes on which to act to mitigate risks. The application of this approach to clinical cell therapy manufacturing in regenerative medicine is also discussed.

  7. An Approach to Improve the Quality of Infrared Images of Vein-Patterns

    OpenAIRE

    Chih-Lung Lin

    2011-01-01

    This study develops an approach to improve the quality of infrared (IR) images of vein-patterns, which usually have noise, low contrast, low brightness and small objects of interest, thus requiring preprocessing to improve their quality. The main characteristics of the proposed approach are that no prior knowledge about the IR image is necessary and no parameters must be preset. Two main goals are sought: impulse noise reduction and adaptive contrast enhancement technologies. In our study, a ...

  8. Service Quality and Customers’ Patronage Decision of Healthcare Insurance Products: ?In-Depth Interview Approach

    OpenAIRE

    Muhammad Sabbir Rahman; Fadi AbdelMuniem AbdelFattah; Osman Bin Mohamad

    2014-01-01

    The purpose of this qualitative research is to explore the role of service quality on customers’ patronage decision of Malaysian health insurance products. Through a critical review of the literature about service quality and customers’ patronage intention this research proposed a relationship of service quality, customer’s satisfaction, perceived value and corporate image on customer’s patronage intention. This research applied qualitative approach (in-depth interview) from 20 participants. ...

  9. Linkages between Total Quality Management and the Outcomes-Based Approach in an Education Environment

    Science.gov (United States)

    de Jager, H. J.; Nieuwenhuis, F. J.

    2005-01-01

    South Africa has embarked on a process of education renewal by adopting outcomes-based education (OBE). This paper focuses on the linkages between total quality management (TQM) and the outcomes-based approach in an education context. Quality assurance in academic programmes in higher education in South Africa is, in some instances, based on the…

  10. Linkages between Total Quality Management and the Outcomes-Based Approach in an Education Environment

    Science.gov (United States)

    de Jager, H. J.; Nieuwenhuis, F. J.

    2005-01-01

    South Africa has embarked on a process of education renewal by adopting outcomes-based education (OBE). This paper focuses on the linkages between total quality management (TQM) and the outcomes-based approach in an education context. Quality assurance in academic programmes in higher education in South Africa is, in some instances, based on the…

  11. Creating patient value in glaucoma care : applying quality costing and care delivery value chain approaches

    NARCIS (Netherlands)

    D.F. de Korne (Dirk); J.C.A. Sol (Kees); T. Custers (Thomas); E. van Sprundel (Esther); B.M. van Ineveld (Martin); H.G. Lemij (Hans); N.S. Klazinga (Niek)

    2009-01-01

    textabstractPurpose: The purpose of this paper is to explore in a specific hospital care process the applicability in practice of the theories of quality costing and value chains. Design/methodology/approach: In a retrospective case study an in-depth evaluation of the use of a quality cost model (QC

  12. A Risk and Standards Based Approach to Quality Assurance in Australia's Diverse Higher Education Sector

    Science.gov (United States)

    Australian Government Tertiary Education Quality and Standards Agency, 2015

    2015-01-01

    The Australian Government Tertiary Education Quality and Standards Agency's (TEQSA's) role is to assure that quality standards are being met by all registered higher education providers. This paper explains how TEQSA's risk-based approach to assuring higher education standards is applied in broad terms to a diverse sector. This explanation is…

  13. Creating patient value in glaucoma care : applying quality costing and care delivery value chain approaches

    NARCIS (Netherlands)

    D.F. de Korne (Dirk); J.C.A. Sol (Kees); T. Custers (Thomas); E. van Sprundel (Esther); B.M. van Ineveld (Martin); H.G. Lemij (Hans); N.S. Klazinga (Niek)

    2009-01-01

    textabstractPurpose: The purpose of this paper is to explore in a specific hospital care process the applicability in practice of the theories of quality costing and value chains. Design/methodology/approach: In a retrospective case study an in-depth evaluation of the use of a quality cost model

  14. APPROACHES TO ANALYZE THE QUALITY OF ROMANIAN TOURISM WEB SITES

    Directory of Open Access Journals (Sweden)

    Lacurezeanu Ramona

    2013-07-01

    The purpose of our work is to analyze travel web-sites, more exactly, whether the criteria used to analyze virtual stores are also adequate for the Romanian tourism product. Following the study, we concluded that the Romanian online tourism web-sites for the Romanian market have the features that we found listed on similar web-sites of France, England, Germany, etc. In conclusion, online Romanian tourism can be considered one of the factors of economic growth.

  15. Approaches to Demonstrating Bankability and Differentiating Product Quality (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Kurtz, S.

    2014-07-01

    As the PV Industry has matured, there is increasing interest in quantifying higher quality so that customers may select products that meet their needs, and investors are demanding high confidence before committing millions of dollars. The community is developing the knowledge and standard methods needed to address these. This talk will give an overview of new developments in the last year including descriptions and status of Qualification Plus (a test protocol that goes beyond the standard qualification tests), a PV-specific version of ISO 9001 (for increased confidence in manufacturing consistency), and the Regional Test Centers (where new products can be tested to quantify performance and durability in multiple climate zones.) Development of PV system-level certification will also be described.

  16. LEAN LABORATORY APPROACHES FOR QUALITY ASSURANCE IN FOOD

    Directory of Open Access Journals (Sweden)

    Laxmana Naik

    2011-09-01

    Full Text Available A lean laboratory is one which is focused on testing products and materials to deliver results in the most efficient way in terms of cost or speed or both; primarily focused on improving measurable performance and reducing costs. The goal of a lean laboratory is to use less effort, less resources and less time to test incoming samples. Laboratories have a critical role to play in establishing and improving process capability and key performance indicator (KPI of the organization. There are inevitably many opinions as to what a lean lab actually is; here is one version fr om. Quality assurance laboratories are crucial to the success of organization and this effectiveness needs to be measurable and demonstrable. To facilitate this, a method of measuring a laboratory's progress towards complete deployment has been created by lean tools. These tools allow laboratories to conduct gap analysis and identify opportunities for improvement.

  17. Measuring the quality of MDT working: an observational approach

    Directory of Open Access Journals (Sweden)

    Taylor Cath

    2012-05-01

    Full Text Available Abstract Background Cancer multidisciplinary teams (MDTs are established in many countries but little is known about how well they function. A core activity is regular MDT meetings (MDMs where treatment recommendations are agreed. A mixed methods descriptive study was conducted to develop and test quality criteria for observational assessment of MDM performance calibrated against consensus from over 2000 MDT members about the “characteristics of an effective MDT”. Methods Eighteen of the 86 ‘Characteristics of Effective MDTs’ were considered relevant and feasible to observe. They collated to 15 aspects of MDT working covering four domains: the team (e.g. attendance, chairing, teamworking; infrastructure for meetings (venue, equipment; meeting organisation and logistics; and patient-centred clinical decision-making (patient-centredness, clarity of recommendations. Criteria for rating each characteristic from ‘very poor’ to ‘very good’ were derived from literature review, observing MDMs and expert input. Criteria were applied to 10 bowel cancer MDTs to assess acceptability and measure variation between and within teams. Feasibility and inter-rater reliability was assessed by comparing three observers. Results Observational assessment was acceptable to teams and feasible to implement. Total scores from 29 to 50 (out of 58 highlighted wide diversity in quality between teams. Eight teams were rated either ‘very good/good’ or ‘very poor/poor’ for at least three domains demonstrating some internal consistency. ‘Very good’ ratings were most likely for attendance and administrative preparation, and least likely for patient-centredness of decision-making and prioritisation of complex cases. All except two characteristics had intra-class correlations of ≥0.50. Conclusions This observational tool (MDT-OARS may contribute to the assessment of MDT performance. Further testing to confirm validity and reliability is required.

  18. Development of rapidly dissolving pellets within the Quality by Design approach.

    Science.gov (United States)

    Karatzas, A A; Politis, S N; Rekkas, D M

    2017-05-01

    The purpose of this study was the development of novel, fast disintegrating, effervescent pellets by employing the direct pelletization technique as a single step process. In line with the Quality by Design (QbD) regulatory framework, statistical experimental design was extensively applied to correlate significant formulation and process variables with the critical quality attributes of the product. Pellets were studied with regards to sphericity, size and size distribution. In contrast to the existing multiparticulate platforms, this development integrated only water-soluble excipients to facilitate the multifunctional use of the final dosage form. The application of a screening fractional factorial design augmented to a full factorial design set the roadmap for the rational selection of the composition and process parameters, revealing in parallel the positive contribution of the powder feeder on the CQAs, when the critical process and formulation factors were properly adjusted. The response surface methodology was exploited for the final process optimization phase, which allowed the construction of appropriate mathematical models connecting the input variables and the CQAs under study. The implementation of the desirability function, lead to the optimum formulation and process settings for the production of pellets with narrow size distribution and geometric mean diameter of approximately 800 μm. In conclusion, using a lean approach supported by design of experiments (DoE) techniques within the QbD framework, a novel multifunctional formulation platform has been developed.

  19. Development and evaluation of paclitaxel nanoparticles using a quality-by-design approach.

    Science.gov (United States)

    Yerlikaya, Firat; Ozgen, Aysegul; Vural, Imran; Guven, Olgun; Karaagaoglu, Ergun; Khan, Mansoor A; Capan, Yilmaz

    2013-10-01

    The aims of this study were to develop and characterize paclitaxel nanoparticles, to identify and control critical sources of variability in the process, and to understand the impact of formulation and process parameters on the critical quality attributes (CQAs) using a quality-by-design (QbD) approach. For this, a risk assessment study was performed with various formulation and process parameters to determine their impact on CQAs of nanoparticles, which were determined to be average particle size, zeta potential, and encapsulation efficiency. Potential risk factors were identified using an Ishikawa diagram and screened by Plackett-Burman design and finally nanoparticles were optimized using Box-Behnken design. The optimized formulation was further characterized by Fourier transform infrared spectroscopy, X-ray diffractometry, differential scanning calorimetry, scanning electron microscopy, atomic force microscopy, and gas chromatography. It was observed that paclitaxel transformed from crystalline state to amorphous state while totally encapsulating into the nanoparticles. The nanoparticles were spherical, smooth, and homogenous with no dichloromethane residue. In vitro cytotoxicity test showed that the developed nanoparticles are more efficient than free paclitaxel in terms of antitumor activity (more than 25%). In conclusion, this study demonstrated that understanding formulation and process parameters with the philosophy of QbD is useful for the optimization of complex drug delivery systems.

  20. A quality by design approach to understand formulation and process variability in pharmaceutical melt extrusion processes.

    Science.gov (United States)

    Patwardhan, Ketaki; Asgarzadeh, Firouz; Dassinger, Thomas; Albers, Jessica; Repka, Michael A

    2015-05-01

    In this study, the principles of quality by design (QbD) have been uniquely applied to a pharmaceutical melt extrusion process for an immediate release formulation with a low melting model drug, ibuprofen. Two qualitative risk assessment tools - Fishbone diagram and failure mode effect analysis - were utilized to strategically narrow down the most influential parameters. Selected variables were further assessed using a Plackett-Burman screening study, which was upgraded to a response surface design consisting of the critical factors to study the interactions between the study variables. In process torque, glass transition temperature (Tg ) of the extrudates, assay, dissolution and phase change were measured as responses to evaluate the critical quality attributes (CQAs) of the extrudates. The effect of each study variable on the measured responses was analysed using multiple regression for the screening design and partial least squares for the optimization design. Experimental limits for formulation and process parameters to attain optimum processing have been outlined. A design space plot describing the domain of experimental variables within which the CQAs remained unchanged was developed. A comprehensive approach for melt extrusion product development based on the QbD methodology has been demonstrated. Drug loading concentrations between 40- 48%w/w and extrusion temperature in the range of 90-130°C were found to be the most optimum. © 2015 Royal Pharmaceutical Society.

  1. Quality of life and cost factors in panic disorder.

    Science.gov (United States)

    Davidson, J R

    1996-01-01

    Quality of life encompasses domains of personal happiness, role fulfillment, and health status. Increasing attention has been paid to the relationship between quality of life and panic disorder, with accumulating evidence now available to suggest impairment in several domains among subjects with panic disorder. This review summarizes the results of community-based and treatment-seeking populations of subjects with panic disorder. Impaired personal happiness, restricted role functioning, and increased use of health services are all described. Evidence suggests that accurate diagnosis and effective treatment can significantly lessen health service utilization, resulting in substantial cost offset and also leading to increased work productivity and personal effectiveness.

  2. Current good manufacturing practices, quality control procedures, quality factors, notification requirements, and records and reports, for infant formula. Final rule.

    Science.gov (United States)

    2014-06-10

    The Food and Drug Administration (FDA or we) is issuing a final rule that adopts, with some modifications, the interim final rule (IFR) entitled "Current Good Manufacturing Practices, Quality Control Procedures, Quality Factors, Notification Requirements, and Records and Reports, for Infant Formula'' (February 10, 2014). This final rule affirms the IFR's changes to FDA's regulations and provides additional modifications and clarifications. The final rule also responds to certain comments submitted in response to the request for comments in the IFR.

  3. Transcription factor motif quality assessment requires systematic comparative analysis [version 2; referees: 2 approved

    Directory of Open Access Journals (Sweden)

    Caleb Kipkurui Kibet

    2016-03-01

    Full Text Available Transcription factor (TF binding site prediction remains a challenge in gene regulatory research due to degeneracy and potential variability in binding sites in the genome. Dozens of algorithms designed to learn binding models (motifs have generated many motifs available in research papers with a subset making it to databases like JASPAR, UniPROBE and Transfac. The presence of many versions of motifs from the various databases for a single TF and the lack of a standardized assessment technique makes it difficult for biologists to make an appropriate choice of binding model and for algorithm developers to benchmark, test and improve on their models. In this study, we review and evaluate the approaches in use, highlight differences and demonstrate the difficulty of defining a standardized motif assessment approach. We review scoring functions, motif length, test data and the type of performance metrics used in prior studies as some of the factors that influence the outcome of a motif assessment. We show that the scoring functions and statistics used in motif assessment influence ranking of motifs in a TF-specific manner. We also show that TF binding specificity can vary by source of genomic binding data. We also demonstrate that information content of a motif is not in isolation a measure of motif quality but is influenced by TF binding behaviour. We conclude that there is a need for an easy-to-use tool that presents all available evidence for a comparative analysis.

  4. A bottom-up approach of stochastic demand allocation in water quality modelling

    Directory of Open Access Journals (Sweden)

    E. J. M. Blokker

    2010-04-01

    Full Text Available An "all pipes" hydraulic model of a drinking water distribution system was constructed with two types of demand allocations. One is constructed with the conventional top-down approach, i.e. a demand multiplier pattern from the booster station is allocated to all demand nodes with a correction factor to account for the average water demand on that node. The other is constructed with a bottom-up approach of demand allocation, i.e., each individual home is represented by one demand node with its own stochastic water demand pattern. This was done for a drinking water distribution system of approximately 10 km of mains and serving ca. 1000 homes. The system was tested in a real life situation.

    The stochastic water demand patterns were constructed with the end-use model SIMDEUM on a per second basis and per individual home. Before applying the demand patterns in a network model, some temporal aggregation was done. The flow entering the test area was measured and a tracer test with sodium chloride was performed to determine travel times. The two models were validated on the total sum of demands and on travel times.

    The study showed that the bottom-up approach leads to realistic water demand patterns and travel times, without the need for any flow measurements or calibration. In the periphery of the drinking water distribution system it is not possible to calibrate models on pressure, because head losses are too low. The study shows that in the periphery it is also difficult to calibrate on water quality (e.g. with tracer measurements, as a consequence of the high variability between days. The stochastic approach of hydraulic modelling gives insight into the variability of travel times as an added feature beyond the conventional way of modelling.

  5. Sleep quality in middle-aged and elderly Chinese: distribution, associated factors and associations with cardio-metabolic risk factors

    Directory of Open Access Journals (Sweden)

    Lin Xu

    2009-05-01

    Full Text Available Abstract Background Poor sleep quality has been associated with increased risk of heart disease, diabetes and mortality. However, limited information exists on the distribution and determinants of sleep quality and its associations with cardio-metabolic risk factors in Chinese populations. We aimed to evaluate this in the current study. Methods A cross-sectional survey conducted in 2005 of 1,458 men and 1,831 women aged 50–70 years from urban and rural areas of Beijing and Shanghai. Using a questionnaire, sleep quality was measured in levels of well, common and poor. Comprehensive measures of socio-demographical and health factors and biomarkers of cardio-metabolic disease were recorded. These were evaluated in association with sleep quality using logistic regression models. Results Half of the population reported good sleep quality. After adjusting for potential confounders, women and Beijing residents had almost half the probability to report good sleep quality. Good physical and mental health (good levels of self-rated health (OR 2.48; 95%CI 2.08 to 2.96 and no depression (OR 4.05; 95%CI 3.12 to 5.26 related to an increased chance of reporting good sleep quality, whereas short sleep duration ( Conclusion Levels of good sleep quality in middle-age and elderly Chinese were low. Gender, geographical location, self-rated health, depression and sleep quantity were major factors associated with sleep quality. Prospective studies are required to distil the factors that determine sleep quality and the effects that sleep patterns exert on cardio-metabolic health.

  6. Sound Quality of Turn Indicator Sounds-Use of aMultidimensional Approach in the Automotive ProductDevelopment

    Institute of Scientific and Technical Information of China (English)

    Verena Wagner; Konrad Wolfgang Kallus

    2015-01-01

    Vehicle sounds are important factors of customer satisfaction and have a decisive influence on the product automobile andits quality impression. It becomes more and more important to connect customer requirements and technical specifications to developa vehicle sound with high quality. The turn indicator sound can be described as one sound, which gives the customer an importantfeedback of correct function performance and can be seen as one of the sounds, which play a role in the customer's perception ofvehicle quality. In a laboratory experimental study, the question was investigated, how a turn indicator sound must be designed to beperceived as pleasant and high-quality. A multidimensional approach was chosen to combine subjective customer assessments,objective psychophysiological responses of the study participants and physical parameters of the sounds. In total, 15 different tumindicator sounds were assessed by 48 subjects. The study shows how the connection of subjective and objective parameters cansupport product development. The multi-dimensional approach helps to derive recommendations for action to improve the soundquality of the product automobile. Also, the study shows a possibility to involve the human factor in a highly technical environment.

  7. Factors associated with low quality of life in schizophrenia

    Directory of Open Access Journals (Sweden)

    Cardoso Clareci Silva

    2005-01-01

    Full Text Available Interest in quality of life in mental health care has been stimulated by the deinstitutionalization of psychiatric patients as well as a parallel interest in understanding the scope of their daily lives. This study aims to investigate the socio-demographic and clinical variables related to low quality of life, using a cross-sectional design to evaluate quality of life by means of the QLS-BR scale. We interviewed a sample of 123 outpatients from a reference mental health center in Divinópolis, Minas Gerais State, Brazil, clinically diagnosed with schizophrenia. Univariate and multivariate logistic regression analyses were carried out. The results showed that low quality of life is associated with one or more of the following: male gender, single marital status, low income plus low schooling, use of three or more prescribed psychoactive drugs, psychomotor agitation during the interview, and current follow-up care. The study identifies plausible indicators for the attention and care needed to improve psychiatric patient treatment.

  8. Do Non-Economic Quality of Life Factors Drive Immigration?

    Science.gov (United States)

    Pacheco, Gail Anne; Rossouw, Stephanie; Lewer, Joshua

    2013-01-01

    This paper contributes to the immigration literature by generating two unique non-economic quality of life (QOL) indices and testing their role on recent migration patterns. Applying the generated QOL indices in conjunction with four independent welfare measures to an augmented gravity model of immigration, this paper finds an insignificant…

  9. Style and Quality in Research Supervision: The Supervisor Dependency Factor.

    Science.gov (United States)

    Kam, Booi Hon

    1997-01-01

    A survey of 250 graduate research students examined the extent of dependency on supervisors in a range of research-related tasks, and how that dependency affected the research supervision process. Results suggest appropriate research supervision has no set prescription, but interactions among quality and style of supervision, role expectations of…

  10. Cervical cancer, quality issues in early detection and prognostic factors

    NARCIS (Netherlands)

    Zaal, A.

    2014-01-01

    It is expected that cervical cancer incidence will reduce in The Netherlands over the next decades, as a result of hrHPV vaccination and hrHPV-based screening. Untill then, quality of care could need some improvements as suggested by the work described in this thesis. Novel tools are being indicated

  11. Do Non-Economic Quality of Life Factors Drive Immigration?

    Science.gov (United States)

    Pacheco, Gail Anne; Rossouw, Stephanie; Lewer, Joshua

    2013-01-01

    This paper contributes to the immigration literature by generating two unique non-economic quality of life (QOL) indices and testing their role on recent migration patterns. Applying the generated QOL indices in conjunction with four independent welfare measures to an augmented gravity model of immigration, this paper finds an insignificant…

  12. Factors Influencing Assessment Quality in Higher Vocational Education

    Science.gov (United States)

    Baartman, Liesbeth; Gulikers, Judith; Dijkstra, Asha

    2013-01-01

    The development of assessments that are fit to assess professional competence in higher vocational education requires a reconsideration of assessment methods, quality criteria and (self)evaluation. This article examines the self-evaluations of nine courses of a large higher vocational education institute. Per course, 4-11 teachers and 3-10…

  13. Factors influencing assessment quality in higher vocational education

    NARCIS (Netherlands)

    Baartman, L.; Gulikers, J.T.M.; Dijkstra, A.

    2013-01-01

    The development of assessments that are fit to assess professional competence in higher vocational education requires a reconsideration of assessment methods, quality criteria and (self)evaluation. This article examines the self-evaluations of nine courses of a large higher vocational education inst

  14. EVALUATION OF QUALITY CATERING SERVICES AS A FACTOR

    Directory of Open Access Journals (Sweden)

    Ewa Cieślik

    2014-09-01

    Full Text Available The aim of this study was to assess the impact of quality catering services on the increase of consumers’ confidence. The survey data were collected among 200 inhabitants of the district town of the province of Silesia taking into account their gender, age and occupational status. The research tool was the authoring questionnaire. The scope of the research included the quality of catering services, including customer service, and the level of customer satisfaction and know why the use of catering services. The results indicate a close correlation between the quality of catering services (cleanliness of premises, interior design, appearance / hygiene service staff and customers’ satisfaction. The majority of the respondents seldom use the food service and catering establishments; they choose affordable business premises, mostly fast food. Then, their attention is paid to their own tastes and prices, of the offered dishes. For the polled a very important criterion for choosing a place is the service staff of the establishment (manners, hygiene, appearance. The quality of catering services is very important for the customers, as it determines the choice of the catering facility and increases consumers’ loyalty in the institution.

  15. WATER QUALITY AND SOCIO-ECONOMICS FACTORS AFFECTING FISH PRODUCTION IN CIRATA RESERVOIR, WEST JAVA, INDONESIA

    OpenAIRE

    Nadia, Istiqomah

    2014-01-01

    The study was aimed to investigate socio-economics factor affecting fish production and to estimate water quality factor affecting fish production in Cirata Reservoir, West Java, Indonesia. Data were obtained from 115 farmers spread over 3 districts in the area of study. Cross section data of socio-economics factors were obtained from the farmer and examined in the study. In addition, historical data of water quality were gathered from the institution. Cobb-Douglass production function was us...

  16. Geoinformatics Approach for Groundwater Prospects and Quality Studies - A Review

    Directory of Open Access Journals (Sweden)

    Rajvir Singh

    2015-06-01

    Full Text Available Water is a prime requirement for all the living and non-living processes. On the earth, 71% is water but the availability of useable fresh water for drinking and other purposes is about 2.8%. Out of this 2.8 % fresh water, the share of groundwater is only 0.6% that makes it more pertinent to conservation, preservation, and management. The urbanization, industrialization, and intensive agricultural practices have put further pressure on the available fresh water. The modern techniques like space technology, GIS and GPS have great utility in mapping, monitoring, planning and management of water resources. The temporal satellite data in different spectral bands and on different spatial resolutions make the remote sensing satellite data highly useful for mapping and monitoring of an area. The geographical information system (GIS has the capability to store, retrieve, edit and represent the data in informative way. The global positioning system (GPS gives the real time geo-coordinates, path and altitude of desired object or terrain. Thus, the geoinformatics have huge potential for solving the problems of groundwater availability and quality, and there is a need to harness the potential of these techniques for societal benefits to provide water everyone.

  17. [The quality of cancer registry. From a methodology approach].

    Science.gov (United States)

    Fajardo-Gutiérrez, Arturo; González-Miranda, Guadalupe

    2011-01-01

    Since 1996 at the unit of epidemiological research of the "Hospital de Pediatría en Centro Medico Nacional Siglo XXI" a cancer registry in children has been done. This registry has been a pioneer with special features like be only in child population attended in Mexico City. The following paper describes the main characteristics of the registry, the strategy used to obtain the data, the quality criterion applied for selecting data like timeliness, validated and complete. A longitudinal and prolective data was obtained. There was a training period for obtaining and register the data. The data was obtained from children with neoplasm attended at the mentioned hospital above. The diagnosis of a solid neoplasm was established by histology and marrow aspirated studies. The population studied was children (0-14 years). It was calculated the incidence (per 1000 000 children/year) by age, sex, diagnosis and place of residence. The trend was evaluated by estimating the average annual percent of change.

  18. Ranking factors involved in product design using a hybrid model of Quality Function Deployment, Data Envelopment Analysis and TOPSIS technique

    Directory of Open Access Journals (Sweden)

    Davood Feiz

    2014-08-01

    Full Text Available Quality function deployment (QFD is one such extremely important quality management tool, which is useful in product design and development. Traditionally, QFD rates the design requirements (DRs with respect to customer requirements, and aggregates the rating to get relative importance score of DRs. An increasing number of studies emphasize on the need to incorporate additional factors, such as cost and environmental impact, while calculating the relative importance of DRs. However, there are different methodologies for driving the relative importance of DRs, when several additional factors are considered. TOPSIS (technique for order preferences by similarity to ideal solution is suggested for the purpose of the research. This research proposes new approach of TOPSIS for considering the rating of DRs with respect to CRs, and several additional factors, simultaneously. Proposed method is illustrated using by step-by-step procedure. The proposed methodology was applied for the Sanam Electronic Company in Iran.

  19. Quality Assurance of Cancer Study Common Data Elements Using A Post-Coordination Approach.

    Science.gov (United States)

    Jiang, Guoqian; Solbrig, Harold R; Prud'hommeaux, Eric; Tao, Cui; Weng, Chunhua; Chute, Christopher G

    2015-01-01

    Domain-specific common data elements (CDEs) are emerging as an effective approach to standards-based clinical research data storage and retrieval. A limiting factor, however, is the lack of robust automated quality assurance (QA) tools for the CDEs in clinical study domains. The objectives of the present study are to prototype and evaluate a QA tool for the study of cancer CDEs using a post-coordination approach. The study starts by integrating the NCI caDSR CDEs and The Cancer Genome Atlas (TCGA) data dictionaries in a single Resource Description Framework (RDF) data store. We designed a compositional expression pattern based on the Data Element Concept model structure informed by ISO/IEC 11179, and developed a transformation tool that converts the pattern-based compositional expressions into the Web Ontology Language (OWL) syntax. Invoking reasoning and explanation services, we tested the system utilizing the CDEs extracted from two TCGA clinical cancer study domains. The system could automatically identify duplicate CDEs, and detect CDE modeling errors. In conclusion, compositional expressions not only enable reuse of existing ontology codes to define new domain concepts, but also provide an automated mechanism for QA of terminological annotations for CDEs.

  20. Constructivist-Visual Mind Map Teaching Approach and the Quality of Students' Cognitive Structures

    Science.gov (United States)

    Dhindsa, Harkirat S.; Makarimi-Kasim; Anderson, O. Roger

    2011-01-01

    This study compared the effects of a constructivist-visual mind map teaching approach (CMA) and of a traditional teaching approach (TTA) on (a) the quality and richness of students' knowledge structures and (b) TTA and CMA students' perceptions of the extent that a constructivist learning environment (CLE) was created in their classes. The sample…

  1. A research approach for quality based design of healthy foods: Dried broccoli as a case study

    NARCIS (Netherlands)

    Oliviero, T.; Verkerk, R.; Dekker, M.

    2013-01-01

    An approach for process design based on optimization of product quality attributes is presented. Adsorption drying of broccoli with retention of its health benefits is taken as an example to illustrate the approach. Related to its content of glucosinolates, broccoli has a high potential to reduce th

  2. The Programmatic Approach; a Flexible and Complex Tool to Achieve Environmental Quality Standards

    NARCIS (Netherlands)

    M.N. Boeve; G.M. van den Broek

    2012-01-01

    This contribution focuses on the integrated or programmatic approaches at both the European and national level, which are used as a tool to attain environmental quality standards. These approaches leave much room for flexibility with respect to the choice of measures to be adopted in order to achiev

  3. A spatial-spectral approach for deriving high signal quality eigenvectors for remote sensing image transformations

    DEFF Research Database (Denmark)

    Rogge, Derek; Bachmann, Martin; Rivard, Benoit

    2014-01-01

    -line surveys, or temporal data sets as computational burden becomes significant. In this paper we present a spatial-spectral approach to deriving high signal quality eigenvectors for image transformations which possess an inherently ability to reduce the effects of noise. The approach applies a spatial...

  4. Assessment of Groundwater Quality of Ilorin Metropolis using Water Quality Index Approach

    Directory of Open Access Journals (Sweden)

    J. A. Olatunji

    2015-06-01

    Full Text Available Groundwater as a source of potable water is becoming more important in Nigeria. Therefore, the need to ascertain the continuing potability of the sources cannot be over emphasised. This study is aimed at assessing the quality of selected groundwater samples from Ilorin metropolis, Nigeria, using the water quality index (WQI method. Twenty two water samples were collected, 10 samples from boreholes and 12 samples from hand dug wells. All these were analysed for their physico – chemical properties. The parameters used for calculating the water quality index include the following: pH, total hardness, total dissolved solid, calcium, fluoride, iron, potassium, sulphate, nitrate and carbonate. The water quality index for the twenty two samples ranged from 0.66 to 756.02 with an average of 80.77. Two of the samples exceeded 100, which is the upper limit for safe drinking water. The high values of WQI from the sampling locations are observed to be due to higher values of iron and fluoride. This study reveals that the investigated groundwaters are mostly potable and can be consumed without treatment. Nonetheless, the sources identified to be unsafe should be treated before consumption.

  5. Factors that affect print quality in thermal dye transfer imaging

    Science.gov (United States)

    Harrison, Daniel J. P.; McInerney, Elizabeth

    1995-04-01

    Thermal dye transfer (TDT) imaging has established itself as the state- of-the-art process for high quality, continuous tone, nonimpact printing. Imaging quality from this process rivals conventional silver halide photography and exceeds other nonimpact printing technologies. Because this output appears to be virtually indistinguishable from photographic prints, there has been an expectation that all the quality attributes of silver halide photography are embodied in a TDT print. However, there are many significant differences that affect output quality between these two technologies. These differences are primarily in color gamut, print artifacts, Dmin, grain/sharpness, and image stability. The range of colors reproducible by a color, hard copy device, known as its color gamut, is dictated primarily by the image- forming dyes used by the device. The size and shape of a device's gamut is controlled by the spectral density distributions of these image forming dyes, the Dmin of the receiver base, the Dmax of each dye, the amount of light scatter, and the spectral distribution of the viewing illuminant. The spectral density distributions of dyes also have an impact on illuminant sensitivity, which is a predictor of how much the color balance of a print will change with a change in illuminant. By determining and then using characteristic curves for various image- forming dyes, we have been able to calculate and compare the color gamuts and illuminant sensitivity of TDT imaging with other technologies (color monitor and silver halide photography, for example). The differences we have found can have a significant impact on output quality, depending upon the application. Compared to conventional photography, thermal dye transfer prints have traditionally had inferior light stability and resistance to damage from fingerprints. In addition, thermal dye transfer prints have been aggressively attacked by plasticized polyvinyl chloride sheets and folders commonly found in

  6. Quality by design case study: an integrated multivariate approach to drug product and process development.

    Science.gov (United States)

    Huang, Jun; Kaul, Goldi; Cai, Chunsheng; Chatlapalli, Ramarao; Hernandez-Abad, Pedro; Ghosh, Krishnendu; Nagi, Arwinder

    2009-12-01

    To facilitate an in-depth process understanding, and offer opportunities for developing control strategies to ensure product quality, a combination of experimental design, optimization and multivariate techniques was integrated into the process development of a drug product. A process DOE was used to evaluate effects of the design factors on manufacturability and final product CQAs, and establish design space to ensure desired CQAs. Two types of analyses were performed to extract maximal information, DOE effect & response surface analysis and multivariate analysis (PCA and PLS). The DOE effect analysis was used to evaluate the interactions and effects of three design factors (water amount, wet massing time and lubrication time), on response variables (blend flow, compressibility and tablet dissolution). The design space was established by the combined use of DOE, optimization and multivariate analysis to ensure desired CQAs. Multivariate analysis of all variables from the DOE batches was conducted to study relationships between the variables and to evaluate the impact of material attributes/process parameters on manufacturability and final product CQAs. The integrated multivariate approach exemplifies application of QbD principles and tools to drug product and process development.

  7. Feedstock Quality Factor Calibration and Data Model Development

    Energy Technology Data Exchange (ETDEWEB)

    Richard D. Boardman; Tyler L. Westover; Garold L. Gresham

    2010-05-01

    The goal of the feedstock assembly operation is to deliver uniform, quality-assured feedstock materials that will enhance downstream system performance by avoiding problems in the conversion equipment. In order to achieve this goal, there is a need for rapid screening tools and methodologies for assessing the thermochemical quality characteristics of biomass feedstock through the assembly process. Laser-induced breakdown spectroscopy (LIBS) has been identified as potential technique that could allow rapid elemental analyses of the inorganic content of biomass feedstocks; and consequently, would complement the carbohydrate data provided by near-infrared spectrometry (NIRS). These constituents, including Si, K, Ca, Na, S, P, Cl, Mg, Fe and Al, create a number of downstream problems in thermochemical processes. In particular, they reduce the energy content of the feedstock, influence reaction pathways, contribute to fouling and corrosion within systems, poison catalysts, and impact waste streams.

  8. Certifying leaders? high-quality management practices and healthy organisations: an ISO-9000 based standardisation approach.

    Science.gov (United States)

    Montano, Diego

    2016-08-05

    The present study proposes a set of quality requirements to management practices by taking into account the empirical evidence on their potential effects on health, the systemic nature of social organisations, and the current conceptualisations of management functions within the framework of comprehensive quality management systems. Systematic reviews and meta-analyses focusing on the associations between leadership and/or supervision and health in occupational settings are evaluated, and the core elements of an ISO 9001 standardisation approach are presented. Six major occupational health requirements to high-quality management practices are identified pertaining to communication processes, organisational justice, role clarity, decision making, social influence processes and management support. It is concluded that the quality of management practices may be improved by developing a quality management system of management practices that ensures not only conformity to product but also to occupational safety and health requirements. Further research may evaluate the practicability of the proposed approach.

  9. Space Station Freedom - Configuration management approach to supporting concurrent engineering and total quality management. [for NASA Space Station Freedom Program

    Science.gov (United States)

    Gavert, Raymond B.

    1990-01-01

    Some experiences of NASA configuration management in providing concurrent engineering support to the Space Station Freedom program for the achievement of life cycle benefits and total quality are discussed. Three change decision experiences involving tracing requirements and automated information systems of the electrical power system are described. The potential benefits of concurrent engineering and total quality management include improved operational effectiveness, reduced logistics and support requirements, prevention of schedule slippages, and life cycle cost savings. It is shown how configuration management can influence the benefits attained through disciplined approaches and innovations that compel consideration of all the technical elements of engineering and quality factors that apply to the program development, transition to operations and in operations. Configuration management experiences involving the Space Station program's tiered management structure, the work package contractors, international partners, and the participating NASA centers are discussed.

  10. Space Station Freedom - Configuration management approach to supporting concurrent engineering and total quality management. [for NASA Space Station Freedom Program

    Science.gov (United States)

    Gavert, Raymond B.

    1990-01-01

    Some experiences of NASA configuration management in providing concurrent engineering support to the Space Station Freedom program for the achievement of life cycle benefits and total quality are discussed. Three change decision experiences involving tracing requirements and automated information systems of the electrical power system are described. The potential benefits of concurrent engineering and total quality management include improved operational effectiveness, reduced logistics and support requirements, prevention of schedule slippages, and life cycle cost savings. It is shown how configuration management can influence the benefits attained through disciplined approaches and innovations that compel consideration of all the technical elements of engineering and quality factors that apply to the program development, transition to operations and in operations. Configuration management experiences involving the Space Station program's tiered management structure, the work package contractors, international partners, and the participating NASA centers are discussed.

  11. Quality attributes and socio-demographic factors affecting channel choices

    OpenAIRE

    Lupin, Beatriz; Rodriguez, Elsa M.

    2012-01-01

    Potato is an important staple food and horticultural crop for Argentina and it is included in almost every meal prepared by households. The annual average per capita consumption of potatoes is 40 kg. Despite the rapid rise of supermarkets, small fruit and vegetable shops still dominate horticultural retail in Argentina. The fresh potato quality is a wide and subjective notion that deals with different kinds of attributes e.g., colour, flavor, nutritional contents, added substances during the ...

  12. Factors influencing quality of life in patients with active tuberculosis

    OpenAIRE

    Cox Victoria C; Marra Fawziah; Marra Carlo A; Palepu Anita; FitzGerald J Mark

    2004-01-01

    Abstract Background With effective treatment strategies, the focus of tuberculosis (TB) management has shifted from the prevention of mortality to the avoidance of morbidity. As such, there should be an increased focus on quality of life (QoL) experienced by individuals being treated for TB. The objective of our study was to identify areas of QoL that are affected by active TB using focus groups and individual interviews. Methods English, Cantonese, and Punjabi-speaking subjects with active T...

  13. Considerations on nonclinical approaches to modeling risk factors of suicidal ideation and behavior.

    Science.gov (United States)

    Goody, S M G; Cannon, K E; Liu, M; Kallman, M J; Martinolle, J P; Mazelin-Winum, L; Giarola, A; Ardayfio, P; Moyer, J A; Teuns, G; Hudzik, T J

    2017-10-01

    Given the serious nature of suicidal ideation and behavior (SIB) and the possibility of treatment-emergent SIB, pharmaceutical companies are now applying more proactive approaches in clinical trials and are considering the value of nonclinical models to predict SIB. The current review summarizes nonclinical approaches to modeling three common risk factors associated with SIB: aggression, impulsivity, and anhedonia. For each risk factor, a general description, advantages and disadvantages, species considerations, nonclinical to clinical translation, and pharmacological validation with respect to treatments associated with SIB are summarized. From this review, several gaps were identified that need to be addressed before use of these nonclinical models can be considered a viable option to predict the relative risk for SIB. Other future directions that may compliment these nonclinical approaches, including the use of selectively-bred or genetically-modified rodent models, transgenic models, gene expression profiling, and biomarker analysis, are discussed. This article was developed with the support of the DruSafe Leadership Group of the International Consortium for Innovation and Quality in Pharmaceutical Development (IQ, www.iqconsortium.org). Copyright © 2017 Elsevier Inc. All rights reserved.

  14. Factors influencing the surface quality of polished tool steels

    Science.gov (United States)

    Rebeggiani, S.; Rosén, B.-G.

    2014-09-01

    Today’s demands on surface quality of moulds for injection moulding of plastic components involve no/low defect contents and roughness levels in the nm-range for high gloss applications. Material properties as well as operating conditions influence the mould finish, and thus the final surface of moulded products. This paper focuses on how particle content and different polishing strategies influence final surface qualities of moulds. Visual estimations of polished tool steel samples were combined with non-contact 3D-surface texture analysis in order to correlate traditional assessments to more quantitative methods, and to be able to analyse the surfaces at nanometre-level. It was found that steels with a lower proportion of particles, like carbides and oxides, gave rise to smoother polished surfaces. In a comparative study of polishers from different polishing shops, it was found that while different surface preparation strategies can lead to similar final roughness, similar preparation techniques can produce high-quality surfaces from different steel grades. However, the non-contact 3D-surface texture analysis showed that not all smooth polished surfaces have desirable functional topographies for injection moulding of glossy plastic components.

  15. Quality assurance and risk management: Perspectives on Human Factors Certification of Advanced Aviation Systems

    Science.gov (United States)

    Taylor, Robert M.; Macleod, Iain S.

    1994-01-01

    This paper is based on the experience of engineering psychologists advising the U.K. Ministry of Defense (MoD) on the procurement of advanced aviation systems that conform to good human engineering (HE) practice. Traditional approaches to HE in systems procurement focus on the physical nature of the human-machine interface. Advanced aviation systems present increasingly complex design requirements for human functional integration, information processing, and cognitive task performance effectiveness. These developing requirements present new challenges for HE quality assurance (QA) and risk management, requiring focus on design processes as well as on design content or product. A new approach to the application of HE, recently adopted by NATO, provides more systematic ordering and control of HE processes and activities to meet the challenges of advanced aircrew systems design. This systematic approach to HE has been applied by MoD to the procurement of mission systems for the Royal Navy Merlin helicopter. In MoD procurement, certification is a judicial function, essentially independent of the service customer and industry contractor. Certification decisions are based on advice from MoD's appointed Acceptance Agency. Test and evaluation (T&E) conducted by the contractor and by the Acceptance Agency provide evidence for certification. Certification identifies limitations of systems upon release to the service. Evidence of compliance with HE standards traditionally forms the main basis of HE certification and significant non-compliance could restrict release. The systems HE approach shows concern for the quality of processes as well as for the content of the product. Human factors certification should be concerned with the quality of HE processes as well as products. Certification should require proof of process as well as proof of content and performance. QA criteria such as completeness, consistency, timeliness, and compatibility provide generic guidelines for

  16. Halitosis: a review of associated factors and therapeutic approach.

    Science.gov (United States)

    Cortelli, José Roberto; Barbosa, Mônica Dourado Silva; Westphal, Miriam Ardigó

    2008-01-01

    Halitosis or bad breath is an oral health condition characterized by unpleasant odors emanating consistently from the oral cavity. The origin of halitosis may be related both to systemic and oral conditions, but a large percentage of cases, about 85%, are generally related to an oral cause. Causes include certain foods, poor oral health care, improper cleaning of dentures, dry mouth, tobacco products and medical conditions. Oral causes are related to deep carious lesions, periodontal disease, oral infections, peri-implant disease, pericoronitis, mucosal ulcerations, impacted food or debris and, mainly, tongue coating. Thus, the aim of the present review was to describe the etiological factors, prevalence data and the therapeutic mechanical and chemical approaches related to halitosis. In general, halitosis most often results from the microbial degradation of oral organic substrates including volatile sulfur compounds (VSC). So far, there are few studies evaluating the prevalence of oral malodor in the world population. These studies reported rates ranging from 22% to more than 50%. The mechanical and chemical treatment of halitosis has been addressed by several studies in the past four decades. Many authors agree that the solution of halitosis problems must include the reduction of the intraoral bacterial load and/or the conversion of VSC to nonvolatile substrates. This could be achieved by therapy procedures that reduce the amount of microorganisms and substrates, especially on the tongue.

  17. Halitosis: a review of associated factors and therapeutic approach

    Directory of Open Access Journals (Sweden)

    José Roberto Cortelli

    2008-08-01

    Full Text Available Halitosis or bad breath is an oral health condition characterized by unpleasant odors emanating consistently from the oral cavity. The origin of halitosis may be related both to systemic and oral conditions, but a large percentage of cases, about 85%, are generally related to an oral cause. Causes include certain foods, poor oral health care, improper cleaning of dentures, dry mouth, tobacco products and medical conditions. Oral causes are related to deep carious lesions, periodontal disease, oral infections, peri-implant disease, pericoronitis, mucosal ulcerations, impacted food or debris and, mainly, tongue coating. Thus, the aim of the present review was to describe the etiological factors, prevalence data and the therapeutic mechanical and chemical approaches related to halitosis. In general, halitosis most often results from the microbial degradation of oral organic substrates including volatile sulfur compounds (VSC. So far, there are few studies evaluating the prevalence of oral malodor in the world population. These studies reported rates ranging from 22% to more than 50%. The mechanical and chemical treatment of halitosis has been addressed by several studies in the past four decades. Many authors agree that the solution of halitosis problems must include the reduction of the intraoral bacterial load and/or the conversion of VSC to nonvolatile substrates. This could be achieved by therapy procedures that reduce the amount of microorganisms and substrates, especially on the tongue.

  18. A Quality by Design Approach to Developing and Manufacturing Polymeric Nanoparticle Drug Products.

    Science.gov (United States)

    Troiano, Greg; Nolan, Jim; Parsons, Donald; Van Geen Hoven, Christina; Zale, Stephen

    2016-11-01

    The translation of nanomedicines from concepts to commercial products has not reached its full potential, in part because of the technical and regulatory challenges associated with chemistry, manufacturing, and controls (CMC) development of such complex products. It is critical to take a quality by design (QbD) approach to developing nanomedicines-using a risk-based approach to identifying and classifying product attributes and process parameters and ultimately developing a deep understanding of the products, processes, and platform. This article exemplifies a QbD approach used by BIND Therapeutics, Inc., to industrialize a polymeric targeted nanoparticle drug delivery platform. The focus of the approach is on CMC affairs but consideration is also given to preclinical, clinical, and regulatory aspects of pharmaceutical development. Processes are described for developing a quality target product profile and designing supporting preclinical studies, defining critical quality attributes and process parameters, building a process knowledge map, and employing QbD to support outsourced manufacturing.

  19. Key Factors of Quality in the Sector of Tourism Services Providers: Case Study: Czech Republic

    Directory of Open Access Journals (Sweden)

    Ida Vajčnerová

    2014-01-01

    Full Text Available The paper summarizes main results of partial research aimed at detection of the key factors affecting quality in the sector of tourism services providers, namely tour operators and travel agencies. A primary questionnaire survey was conducted; the researched factors were distributed in the context of service quality dimensions (Grönroos model; the dimensions were tested in relation to sex, age and education of the respondents (ANOVA; Brown-Forsythe test. Assurance was identified as the most important dimension. The output of the study is determining the significance of individual quality factors from the perspective of a potential customer when selecting a service provider.

  20. Cluster and factor analyses using water quality data in the Sapkyo reservoir watershed

    Energy Technology Data Exchange (ETDEWEB)

    Rim, Chang-Soo [Chungwoon University, Hongsung(Korea); Shin, Jae-Ki [Inje University, Kimhae(Korea)

    2002-04-30

    The monthly water quality data measured at 19 stations located in the Sapkyo reservoir watershed were clustered into 2 to 7 clusters and factor analysis was conducted to characterize the water quality, using the information obtained from cluster analysis. The result of cluster analysis shows that Sapkyo reservoir and each stream (Sapkyo stream, Muhan stream and Kokkyo stream) in Sapkyo reservoir watershed have their own water quality characteristics. The result of water quality analysis indicates that the concentration of suspended solids from Sapkyo reservoir is much higher than those of other streams, and which is probably because of increment of phytoplankton biomass with rich nutrient flowing into Sapkyo reservoir from the upper stream of watershed. Furthermore, the concentrations of biochemical oxygen demand and chemical oxygen demand were 3.5 to 4.8 times and 1.7 to 2.5 times those of other streams, respectively. The overall water quality of Sapkyo reservoir watershed was considered to exceed eutrophic condition. Based on factor analysis, the water quality characteristics of Sapkyo stream and Muhan stream were closely related with farm land and residence. The water quality of Kokkyo stream was influenced by superabundant organic matter flowing from Chonan city and district wastewater treatment plant located in the upper stream of Kokkyo stream. The water quality factor influencing Sapkyo reservoir was closely related with water quality factors of other three streams. (author). 20 refs., 6 tabs., 3 figs.

  1. Quality of synthetic speech perceptual dimensions, influencing factors, and instrumental assessment

    CERN Document Server

    Hinterleitner, Florian

    2017-01-01

    This book reviews research towards perceptual quality dimensions of synthetic speech, compares these findings with the state of the art, and derives a set of five universal perceptual quality dimensions for TTS signals. They are: (i) naturalness of voice, (ii) prosodic quality, (iii) fluency and intelligibility, (iv) absence of disturbances, and (v) calmness. Moreover, a test protocol for the efficient indentification of those dimensions in a listening test is introduced. Furthermore, several factors influencing these dimensions are examined. In addition, different techniques for the instrumental quality assessment of TTS signals are introduced, reviewed and tested. Finally, the requirements for the integration of an instrumental quality measure into a concatenative TTS system are examined.

  2. Vibration factors impact analysis on aerial film camera imaging quality

    Science.gov (United States)

    Xie, Jun; Han, Wei; Xu, Zhonglin; Tan, Haifeng; Yang, Mingquan

    2017-08-01

    Aerial film camera can acquire ground target image information advantageous, but meanwhile the change of aircraft attitude, the film features and the work of camera inside system could result in a vibration which could depress the image quality greatly. This paper presented a design basis of vibration mitigation stabilized platform based on the vibration characteristic of the aerial film camera and indicated the application analysis that stabilized platform could support aerial camera to realize the shoot demand of multi-angle and large scale. According to the technique characteristics of stabilized platform, the development direction are high precision, more agility, miniaturization and low power.

  3. Pediatric Coccidioidomycosis Patients: Perceptions, Quality of Life and Psychosocial Factors

    Directory of Open Access Journals (Sweden)

    Erin Mary Gaab

    2015-08-01

    Full Text Available Research investigating the effects of coccidioidomycosis (valley fever on children and the psychosocial implications of this disease in general is lacking. This study reviews what is known about pediatric coccidioidomycosis patients. It documents the psychological functioning, quality of life, and illness perceptions of a sample of coccidioidomycosis patient families. Primary caregivers of pediatric patients and patients from a major hospital in the San Joaquin Valley of California were interviewed regarding their perceptions of disease detection, access to care and the patient/family experience.

  4. Pediatric Coccidioidomycosis Patients: Perceptions, Quality of Life and Psychosocial Factors

    Science.gov (United States)

    Gaab, Erin Mary; Naeem, Fouzia

    2015-01-01

    Research investigating the effects of coccidioidomycosis (valley fever) on children and the psychosocial implications of this disease in general is lacking. This study reviews what is known about pediatric coccidioidomycosis patients. It documents the psychological functioning, quality of life, and illness perceptions of a sample of coccidioidomycosis patient families. Primary caregivers of pediatric patients and patients from a major hospital in the San Joaquin Valley of California were interviewed regarding their perceptions of disease detection, access to care and the patient/family experience. PMID:27417796

  5. Identifying approaches for assessing methodological and reporting quality of systematic reviews

    DEFF Research Database (Denmark)

    Pussegoda, Kusala; Turner, Lucy; Garritty, Chantelle

    2017-01-01

    there are potential gaps in research best-practice guidance materials. The aims of this study are to identify reports assessing the methodological quality (MQ) and/or reporting quality (RQ) of a cohort of SRs and to assess their number, general characteristics, and approaches to 'quality' assessment over time......BACKGROUND: The methodological quality and completeness of reporting of the systematic reviews (SRs) is fundamental to optimal implementation of evidence-based health care and the reduction of research waste. Methods exist to appraise SRs yet little is known about how they are used in SRs or where....... CONCLUSIONS: The methods used to assess quality of SRs are diverse, and none has become universally accepted. The most commonly used quality assessment tools are AMSTAR, OQAQ, and PRISMA. As new tools and guidelines are developed to improve both the MQ and RQ of SRs, authors of methodological studies...

  6. Factors affecting health-related quality of life in patients after femoral neck fracture.

    Science.gov (United States)

    Valavičienė, Rasa; Smailys, Alfredas; Macijauskienė, Jūratė; Hommel, Ami

    2010-01-01

    Quality of life in patients with femoral neck fracture is an issue frequently discussed in the literature. There is ongoing research on identifying factors that have an impact on quality of life in this particular group of patients. A great variety of factors affecting quality of life and lack of information on their importance encouraged us to perform a systematic literature review analyzing quality of life of patients who sustained femoral neck fracture. The search was performed in the PubMed and Medline databases according to the selected key words. In our systematic review, we included clinical and clinical randomized trials investigating patients with femoral neck fracture and their quality of life. Our analysis showed that treatment of femoral neck fracture with hip replacement was superior to osteosynthesis with regard to patients' quality of life. The data regarding the impact of different rehabilitation programs on quality of life were controversial; a few reports showed that special rehabilitation programs were associated with better health-related quality life. However, other studies did not report any differences in patients' quality of life when different rehabilitation programs were applied. Patient's nutrition may be an important factor affecting the quality of life in patients with femoral neck fractures; however, data supporting this fact are insufficient.

  7. Quality management and safety culture in medicine - Do standard quality reports provide insights into the human factor of patient safety?

    Science.gov (United States)

    Wischet, Werner; Schusterschitz, Claudia

    2009-12-15

    In 1999 the Institute of Medicine (IOM) published the landmark report "To err is human: building a safer healthcare system" highlighting critical deficiencies within the area of patient safety. As a consequence, safety culture evolved as a core component of quality management in medicine. Purpose of the investigation at hand was to find out to what extent this is reflected in standard quality reports issued by German hospitals providing maximum medical care. Reports issued for the year 2006 were analysed with respect to the appearance of indicators for the presence of a safety culture. Results suggest that despite the huge awareness for patient safety caused by the IOM report, the topic of safety culture does not get the anticipated attention within the quality reports. This may indicate that the current requirements for the quality reports do not facilitate transparency when it comes to the human factor of patient safety.

  8. A Survey on Socio-Economic Factors in Relation to Quality of Life

    Directory of Open Access Journals (Sweden)

    Habib Ahmadi

    2009-10-01

    Full Text Available AbstractThis study has been performed by quantitative approach, survey method, and questionnaire technique.The theoretical framework has been synthesized from Maslow's theory of hierarchical needs, and humanecological-systems theory. Based on the main concepts of the theories, and regarding the populationcharacteristics, some indicators have been extracted. Data have been collected from 400 samples, calculatedby Cochran' formulae, residing in Birjand city at the age of 15-65 years old with multistage cluster samplingmethod. Our basic assumption is that the intensity and direction of Quality of Life is subjective-objectiveand in turn, it is influenced and determined by subjective-objective factors. On this basis, by SPSS programand statistics such as analysis of variance and univariate regression, the relationships between Quality ofLife and nine independent variables were analyzed. These variables include: social origin, employmentposition, level of education, occupational rating, level of income, benefitting from networks of socialsupport, socialization manner in family, using mass media, and modern/traditional attitudes. The resultsshow that all of these nine relationships have been significant and positive. Additionally, in multivariateregression the five variables –level of education, socialization manner in family, level of using mass media,level of benefitting from social support networks, and occupational rating— have been included in theequation, and they have collectively explained 44 percent of variances of dependent variable.

  9. Improvement of the indoor air quality. An integral approach; Verbetering van de luchtkwaliteit. Een integrale benadering

    Energy Technology Data Exchange (ETDEWEB)

    Bluyssen, Ph. M. [TNO Bouw en Ondergrond, Delft (Netherlands)

    2009-10-15

    There seems to be a discrepancy between current Indoor Air Quality standards and end-users wishes and demands. Indoor air quality can be approached from three points of view: (1) the human, (2) the indoor air of the space and (3) the sources contributing to indoor air pollution. Standards currently in use mainly address the indoor air of the space. Other or additional recommendations and guidelines are required to improve indoor air quality. Even though we do not fully understand the mechanisms behind the physical, chemical, physiological and psychological processes, it is still possible to identify the different ways to be taken: regulatory, political and social (awareness), technical (process and product) and scientific. Besides the fact that there is an urgent need to involve medicine and neuropsychology in research to investigate the mechanisms behind dose-response, health effects and interactions between and with the other factors and parameters of the indoor environment and the human body and mind, a holistic approach is required including the sources, the air and last but not least the human beings (occupants) themselves. This paper mainly focuses on the European situation. [Dutch] Er lijkt een discrepantie te bestaan tussen de huidige richtlijnen voor binnenluchtkwaliteit en de wensen en eisen van eindgebruikers. Binnenluchtkwaliteit kan op drie manieren worden benaderd: vanuit de mens, de binnenlucht in de ruimte en vanuit de bronnen die aan de binnenluchtverontreiniging bijdragen. Huidige richtlijnen adresseren vooral de binnenlucht in een ruimte. Andere of extra aanbevelingen en richtlijnen zijn nodig om de binnenluchtkwaliteit te verbeteren. Ondanks dat we de mechanismen achter de fysieke, chemische, fysiologische en psychologische processen niet volledig begrijpen, is het toch mogelijk, om de verschillende wegen (regelgeving, politiek-sociale (besef/bewustzijn), technisch (proces en product) en wetenschappelijk), die bewandeld kunnen worden uit te

  10. Factor Analysis 01- Healthcare Service Quality In Medan Government Hospital

    OpenAIRE

    Lubis, Arlina Nurbaity; Lumbanraja, Prihatin; Lubis, Rahmawaty; Hasibuan, Beby Kendida

    2016-01-01

    Service sector increases rapidly especially in Indonesia. This can be seen from the distribution of the percentage of Product Domestic Bruto (PDB) based on job vacancy showing that the service sector contribution approaches 50%. One of the service/care industries with rapid growth is healthcare service. It can be seen from the government plan year 2015-2016 to do healthcare reinforcement. Generally, healthcare is identically related to hospital. A hospital is a professional healthcare institu...

  11. Bs → f0(980) Transition Form Factors Within the kT Factorization Approach

    Institute of Scientific and Technical Information of China (English)

    ZENG Dai-Min; FANG Zhen-Yun

    2013-01-01

    In the paper,we apply the kT factorization approach to deal with the Bs → f0(980) transition form factors in the large recoil regions,i.e.the small q2 regions.For the purpose,we adopt the B-meson wave-functions ΨB,ψ B and δ that include the three-Fock states contributions to do our discussion.Although the scalar meson f0(980) is widely perceived as the 4-quark bound state (scenario 2),but the distribution amplitudes of 4-quark states are still unknown to us,so we adopt 2-quark model (scenario 1) for scalar meson f0(980) in our discussion.By varying the B-meson wave-function parameters within their reasonable regions,we obtain F0(0) =F+(0) =0.20 ± 0.02,FT(0) =0.24 ± 0.02.Our present results for these form factors are consistent with the light-cone sum rule results obtained in the literature.

  12. The Impact of Soft Factors on Quality Improvement in Manufacturing Industry

    Science.gov (United States)

    Chan, Shiau Wei; Fauzi Ahmad, Md; Kong, Mei Wan

    2017-08-01

    Nowadays, soft factors have become the key factors of success in quality improvement of an organisation. Many organisations have neglected the importance of soft factors, this may influence the organisational performance. Hence, the purpose of this research is to examine the impact of soft factors on quality improvement in manufacturing industries. Six hypotheses were examined while considering six dimensions of soft factors including management commitment, customer focus, supplier relationship, employee involvement, training and education, and reward and recognition that have a positive impact on quality improvement. In this study, eighty one managers from the quality department were randomly selected in the manufacturing industry in Batu Pahat, Johor. The questionnaires were distributed to them. The researcher analysed the quantitatively collected data using descriptive analysis and correlation analysis. The findings of this study revealed that all soft factors are correlated to the quality improvement in an organisation with a high significant value but the regression analysis shows that the supplier relationship and employee involvement has more significant impact on quality improvement as compared to other soft factors which contributes of this study.

  13. Assessing the quality of risk factor survey data: lessons from the WHO MONICA Project.

    Science.gov (United States)

    Tolonen, Hanna; Dobson, Annette; Kulathinal, Sangita

    2006-02-01

    Survey data quality is a combination of the representativeness of the sample, the accuracy and precision of measurements, data processing and management with several subcomponents in each. The purpose of this paper is to show how, in the final risk factor surveys of the WHO MONICA Project, information on data quality were obtained, quantified, and used in the analysis. In the WHO MONICA (Multinational MONItoring of trends and determinants in CArdiovascular disease) Project, the information about the data quality components was documented in retrospective quality assessment reports. On the basis of the documented information and the survey data, the quality of each data component was assessed and summarized using quality scores. The quality scores were used in sensitivity testing of the results both by excluding populations with low quality scores and by weighting the data by its quality scores. Detailed documentation of all survey procedures with standardized protocols, training, and quality control are steps towards optimizing data quality. Quantifying data quality is a further step. Methods used in the WHO MONICA Project could be adopted to improve quality in other health surveys.

  14. Modelling nutrient concentration to determine the environmental factors influencing grass quality

    CSIR Research Space (South Africa)

    Dudeni-Tlhone, N

    2010-10-01

    Full Text Available This paper uses the spatial and the least squares (Analysis of Covariance-ANCOVA) regression methods to evaluate the important environmental factors in estimating quality grass for grazing (based on the nitrogen (N) content in grass...

  15. Monolithic distributed Bragg reflector cavities in Al2O3 with quality factors exceeding one million

    NARCIS (Netherlands)

    Bernhardi, Edward; van Wolferen, Hendricus A.G.M.; Worhoff, Kerstin; de Ridder, R.M.; Pollnau, Markus

    Monolithic distributed Bragg reflector (DBR) cavities with quality factors exceeding one million have been realized in aluminum oxide channel waveguides. This technology enabled the successful demonstration of the first DBR laser in this waveguide platform.

  16. Fabricating centimeter-scale high quality factor two-dimensional periodic photonic crystal slabs.

    Science.gov (United States)

    Lee, Jeongwon; Zhen, Bo; Chua, Song-Liang; Shapira, Ofer; Soljačić, Marin

    2014-02-10

    We present a fabrication route for centimeter-scale two-dimensional defect-free photonic crystal slabs with quality factors bigger than 10,000 in the visible, together with a unique way to quantify their quality factors. We fabricate Si(3)N(4) photonic crystal slabs, and perform an angle-resolved reflection measurement. This measurement data is used to retrieve the quality factors of the slabs by fitting it to a model based on temporal coupled-mode theory. The macroscopic nature of the structure and the high quality factors of their resonances could open up new opportunities for realizing efficient macroscale optoelectronic devices such as sensors, lasers, and energy harvesting systems.

  17. Implementing composite quality metrics for bipolar disorder: towards a more comprehensive approach to quality measurement

    OpenAIRE

    Kilbourne, Amy M.; Farmer Teh, Carrie; Welsh, Deborah; Pincus, Harold Alan; Lasky, Elaine; Perron, Brian; Bauer, Mark S

    2010-01-01

    Objective We implemented a set of processes of care measures for bipolar disorder that reflect psychosocial, patient preference, and continuum of care approaches to mental health, and examined whether veterans with bipolar disorder receive care concordant with these practices. Method Data from medical record reviews were used to assess key processes of care for 433 VA mental health outpatients with bipolar disorder. Both composite and individual processes of care measures were ope...

  18. Change in Quality of Life after Rehabilitation: Prognostic Factors for Visually Impaired Adults

    Science.gov (United States)

    Langelaan, Maaike; de Boer, Michiel R.; van Nispen, Ruth M. A.; Wouters, Bill; Moll, Annette C.; van Rens, Ger H. M. B.

    2009-01-01

    The overall aim of rehabilitation for visually impaired adults is to improve the quality of life and (societal) participation. The objectives of this study were to obtain the short-term and long-term outcome of a comprehensive rehabilitation programme on quality of life for visually impaired adults, and prognostic baseline factors responsible for…

  19. Bloch-Wave Engineered Submicron Diameter Micropillars with Quality Factors Exceeding 10,000

    DEFF Research Database (Denmark)

    Hofling, S.; Lermer, M.; Gregersen, Niels;

    2011-01-01

    Adiabatic design submicron diameter quantum-dot micropillars have been designed and implemented for cavity quantum electrodynamics experiments. Ultra-high experimental quality factors (>10,000) are obtained for submicron diameters and strong light-matter interaction is observed.......Adiabatic design submicron diameter quantum-dot micropillars have been designed and implemented for cavity quantum electrodynamics experiments. Ultra-high experimental quality factors (>10,000) are obtained for submicron diameters and strong light-matter interaction is observed....

  20. On the potential impact of the newly proposed quality factors on space radiation protection

    Science.gov (United States)

    Wilson, John W.; Townsend, Lawrence W.; Cucinotta, Francis A.

    1987-01-01

    The recently proposed changes in the defined quality factor hold great potential for easing some of the protection requirements from electrons and protons in the near-Earth environment. At the same time, the high Linear Energy Transfer (LET) components play an even more important role which must be further evaluated. Several recommendations are made which need to be addressed before these new quality factors can be implemented into space radiation potection practice.

  1. QUALITY OF NATIONAL ECONOMIC GROWTH: FACTORS AND DETERMINANTS

    Directory of Open Access Journals (Sweden)

    Nikolaj I. Komkov

    2015-01-01

    Full Text Available The subject / topic: TThe theme of this article is very relevant in the light of changes in the global geo-economic structure and changing the role and place ofRussiain world economic and geopolitical relations. The article deals with the basic aspects of national economic growth, which slowed down in the last three years. The main reason for slowing national economic growth is associated with the depletion of the reserves of the traditional export-oriented development of the Russian economy, as well as problems with sluggish innovative transformation. In this paper, based on a systematic analysis of economic processes and the interpretation of analytical data, addresses the general theoretical and methodological aspects of the quality of economic development, as well as practical guidelines and recommendations related to sustainable national socio-economic development in the context of external constraints.The purpose / objectives: The aim of the article is to analyze the theoretical and methodological aspects of the quality of economic development of the Russian economy, which happened in the face of economic sanctions. Objectives of the article: justify practical directions and recommendations related to sustainable national socio-economic development in the context of external constraints, determine the prospects for the economy of theRussian Federationin the conditions of the introduction of sectoral sanctions by Western countries. Methodology:Methodological basis of this article are the comparative and economic-statistical methods of analysis.The Results: The study revealed that the harsh environment (sanctions, depreciation of the ruble, and others. Require surgical intervention and adjustments not only the current socio-economic plans, but also to take urgent measures to ensure the development prospects. The most important decision is the degree of support advanced scientific and technical programs and the creation of new domestic

  2. Improvement of the quality factor of single crystal diamond mechanical resonators

    Science.gov (United States)

    Liao, Meiyong; Toda, Masaya; Sang, Liwen; Teraji, Tokuyuki; Imura, Masataka; Koide, Yasuo

    2017-02-01

    Single-crystal diamond (SCD) has the potential to boost microelectromechanical system (MEMS) with unprecedented performance in terms of its intrinsic mechanical, chemical, and electronic properties, especially in the applications under extreme conditions. On the basis of the analysis of the energy dissipation in diamond mechanical resonators, the authors report on the marked improvement of the quality factor of SCD-MEMS resonators. Ion implantation assisted lift-off technique (IAL) is utilized to fabricate the SCD resonators. The quality factor of the resonator fabricated from the ion-damaged SCD layer alone is as low as 100-300 owing to the bulk or surface defects. The growth of homoepitaxial layers on the ion-implanted SCD substrates significantly improves the quality factor by more than 100 times. Cantilevers made of SCD epilayers of different thicknesses are examined. It is found that the quality factor increases with increasing the epilayer thickness. The maximum quality factor of the SCD cantilevers fabricated by the IAL technique reaches 3.9 × 104. A bilayer model is proposed to describe the variation of the quality factor.

  3. A Factor Analytic Approach to Symptom Patterns in Dementia

    Directory of Open Access Journals (Sweden)

    Lars Gustafson

    2011-01-01

    Full Text Available Previous publications have shown a high diagnostic sensitivity and specificity of three short clinical rating scales for Alzheimer's disease (AD, frontotemporal dementia (FTD, and vascular dementia (VaD validated against neuropathological (NP diagnoses. In this study, the aim was to perform an exploratory factor analysis of the items in these clinical rating scales. The study included 190 patients with postmortem diagnoses of AD (n=74, VaD (n=33, mixed AD/VaD (n=31, or FTD (n=52. The factor analysis produced three strong factors. Factor 1 contained items describing cerebrovascular disease, similar to the Hachinski Ischemic Score. Factor 2 enclosed major clinical characteristics of FTD, and factor 3 showed a striking similarity to the AD scale. A fourth symptom cluster was described by perception and expression of emotions. The factor analyses strongly support the construct validity of the diagnostic rating scales.

  4. Identifying Items to Assess Methodological Quality in Physical Therapy Trials: A Factor Analysis

    Science.gov (United States)

    Cummings, Greta G.; Fuentes, Jorge; Saltaji, Humam; Ha, Christine; Chisholm, Annabritt; Pasichnyk, Dion; Rogers, Todd

    2014-01-01

    Background Numerous tools and individual items have been proposed to assess the methodological quality of randomized controlled trials (RCTs). The frequency of use of these items varies according to health area, which suggests a lack of agreement regarding their relevance to trial quality or risk of bias. Objective The objectives of this study were: (1) to identify the underlying component structure of items and (2) to determine relevant items to evaluate the quality and risk of bias of trials in physical therapy by using an exploratory factor analysis (EFA). Design A methodological research design was used, and an EFA was performed. Methods Randomized controlled trials used for this study were randomly selected from searches of the Cochrane Database of Systematic Reviews. Two reviewers used 45 items gathered from 7 different quality tools to assess the methodological quality of the RCTs. An exploratory factor analysis was conducted using the principal axis factoring (PAF) method followed by varimax rotation. Results Principal axis factoring identified 34 items loaded on 9 common factors: (1) selection bias; (2) performance and detection bias; (3) eligibility, intervention details, and description of outcome measures; (4) psychometric properties of the main outcome; (5) contamination and adherence to treatment; (6) attrition bias; (7) data analysis; (8) sample size; and (9) control and placebo adequacy. Limitation Because of the exploratory nature of the results, a confirmatory factor analysis is needed to validate this model. Conclusions To the authors' knowledge, this is the first factor analysis to explore the underlying component items used to evaluate the methodological quality or risk of bias of RCTs in physical therapy. The items and factors represent a starting point for evaluating the methodological quality and risk of bias in physical therapy trials. Empirical evidence of the association among these items with treatment effects and a confirmatory factor

  5. Identifying items to assess methodological quality in physical therapy trials: a factor analysis.

    Science.gov (United States)

    Armijo-Olivo, Susan; Cummings, Greta G; Fuentes, Jorge; Saltaji, Humam; Ha, Christine; Chisholm, Annabritt; Pasichnyk, Dion; Rogers, Todd

    2014-09-01

    Numerous tools and individual items have been proposed to assess the methodological quality of randomized controlled trials (RCTs). The frequency of use of these items varies according to health area, which suggests a lack of agreement regarding their relevance to trial quality or risk of bias. The objectives of this study were: (1) to identify the underlying component structure of items and (2) to determine relevant items to evaluate the quality and risk of bias of trials in physical therapy by using an exploratory factor analysis (EFA). A methodological research design was used, and an EFA was performed. Randomized controlled trials used for this study were randomly selected from searches of the Cochrane Database of Systematic Reviews. Two reviewers used 45 items gathered from 7 different quality tools to assess the methodological quality of the RCTs. An exploratory factor analysis was conducted using the principal axis factoring (PAF) method followed by varimax rotation. Principal axis factoring identified 34 items loaded on 9 common factors: (1) selection bias; (2) performance and detection bias; (3) eligibility, intervention details, and description of outcome measures; (4) psychometric properties of the main outcome; (5) contamination and adherence to treatment; (6) attrition bias; (7) data analysis; (8) sample size; and (9) control and placebo adequacy. Because of the exploratory nature of the results, a confirmatory factor analysis is needed to validate this model. To the authors' knowledge, this is the first factor analysis to explore the underlying component items used to evaluate the methodological quality or risk of bias of RCTs in physical therapy. The items and factors represent a starting point for evaluating the methodological quality and risk of bias in physical therapy trials. Empirical evidence of the association among these items with treatment effects and a confirmatory factor analysis of these results are needed to validate these items.

  6. Omic approaches to quality biomarkers for stored platelets: are we there yet?

    Science.gov (United States)

    Kulkarni, Sandhya; Kannan, Meganathan; Atreya, Chintamani D

    2010-07-01

    At present, there is no single biomarker that serves as the "gold standard" predictive of the quality of stored platelets used for transfusion. Some of the measurable features of platelets such as morphology, biochemical status, physiologic response to osmotic stress and agonist-induced changes, and measurement of process-associated activation indicators of platelets are considered useful in assessing the in vitro quality of stored platelets. Such in vitro measurements combined with in vivo survival estimations using radiolabeled platelets in healthy volunteers provide reasonable estimates of in vivo platelet function after transfusion. Thus, the current practice of estimating the quality and functional aspects of ex vivo stored platelets involves utilization of a battery of tests that dates back to pre-omic era. On the other hand, during the last decade, seminal discoveries have been made in platelet molecular and cell biology by using "omic"-based approaches such as proteomics, genomics, and transcriptomics. Can we mobilize some of these discoveries toward developing reliable quality biomarkers for stored platelets? To address this topic, we briefly review current practices and provide insights into some of the omic approaches that could be helpful in identifying quality storage biomarkers of platelets in the near future. We also briefly discuss here some of the challenges in using proteomic approaches and advantages of using one of the transcriptomics approaches toward platelet biomarker development.

  7. Market-Based Approaches to Quality Assessment and Management of Higher Education in the Republic of Kazakhstan

    Science.gov (United States)

    Valikhanova, Zarina

    2015-01-01

    This article considers the problems of the definition of quality in the educational sphere. Alternative approaches to the concept of quality of education and its evaluation are determined given the different approaches of scientists and experts. The most important criteria in assessing the quality is distinguished and formed in the matrix for…

  8. Nutrition myths - the factor influencing the quality of children's diets

    Directory of Open Access Journals (Sweden)

    Slávka Mrosková

    2016-03-01

    Full Text Available Aim: To analyse the influence of parents' belief in nutrition myths on the frequency of their serving certain foods to their children. Design: Cross-sectional study. Methods: Survey carried out with 297 respondents - parents of children aged 5-18 years. The data collection took place between September 2013 and December 2014. The questionnaire focussed on 14 nutrition myths related to selected foods (milk, dairy products, meat, offal, fruit, vegetables, eggs, fish, legumes, soya, and flour dishes. At the same time, the parents reported the frequency of their serving the monitored foods to their children. In the statistical analysis, Spearman's rank correlation coefficient was used. Results: For nine nutrition myths we found significant negative coefficients between a certain nutrition myth and the frequency of the serving of the food. The nutrition myths related to the consumption of fish (r = -0.328, eggs (r = -0.203, soya (r = -0.301; -0.290, offal (r = -0.155, meat (r = -0.128, milk (r = -0.272; -0.254, and fruit/vegetables (r = -0.104. Conclusion: The belief in nutrition myths appears to be a determinant modifying parental behaviour and subsequently the quality of children's diets.

  9. Groundwater quality assessment of one former industrial site in Belgium using a TRIAD-like approach

    Energy Technology Data Exchange (ETDEWEB)

    Crevecoeur, Sophie [Aquapole, Laboratory of Animal Ecology and Ecotoxicology (LEAE), University of Liege, Allee du 6 Aout 15, 4000 Liege (Belgium); Debacker, Virginie, E-mail: Virginie.Debacker@ulg.ac.be [Aquapole, Laboratory of Animal Ecology and Ecotoxicology (LEAE), University of Liege, Allee du 6 Aout 15, 4000 Liege (Belgium); Joaquim-Justo, Celia [Aquapole, Laboratory of Animal Ecology and Ecotoxicology (LEAE), University of Liege, Allee du 6 Aout 15, 4000 Liege (Belgium); Gobert, Sylvie [Laboratory of Oceanology, University of Liege, Allee du 6 Aout 15, 4000 Liege (Belgium); Scippo, Marie-Louise [Laboratory of Food Analysis, University of Liege, Boulevard de Colonster 20, 4000 Liege (Belgium); Dejonghe, Winnie [Separation and Conversion Technology, Flemish Institute for Technological Research (VITO), Industriezone Vlasmeer 7, 2400 Mol (Belgium); Martin, Patrick [Royal Belgian Institute of Natural Sciences (RBINSc), Rue Vautier 29, 1000 Bruxelles (Belgium); Thome, Jean-Pierre [Aquapole, Laboratory of Animal Ecology and Ecotoxicology (LEAE), University of Liege, Allee du 6 Aout 15, 4000 Liege (Belgium)

    2011-10-15

    Contaminated industrial sites are important sources of pollution and may result in ecotoxicological effects on terrestrial, aquatic and groundwater ecosystems. An effect-based approach to evaluate and assess pollution-induced degradation due to contaminated groundwater was carried out in this study. The new concept, referred to as 'Groundwater Quality TRIAD-like' (GwQT) approach, is adapted from classical TRIAD approaches. GwQT is based on measurements of chemical concentrations, laboratory toxicity tests and physico-chemical analyses. These components are combined in the GwQT using qualitative and quantitative (using zero to one subindices) integration approaches. The TRIAD approach is applied for the first time on groundwater from one former industrial site located in Belgium. This approach will allow the classification of sites into categories according to the degree of contaminant-induced degradation. This new concept is a starting point for groundwater characterization and is open for improvement and adjustment. - Highlights: > This study presents the first application of the TRIAD approach on groundwater system. > Groundwater Quality TRIAD-like approach is based on measurements of chemical concentrations, laboratory toxicity tests and physico-chemical analyses. > None of the three TRIAD components could reliably predict the other one. - This study presents the first application of the TRIAD approach on groundwater system. None of the TRIAD components (chemistry, physico-chemistry and ecotoxicity) could reliably predict the other one.

  10. A General Approach of Quality Cost Management Suitable for Effective Implementation in Software Systems

    Directory of Open Access Journals (Sweden)

    Stelian BRAD

    2010-01-01

    Full Text Available Investments in quality are best quantified by implementing and managing quality cost systems. A review of various opinions coming from practitioners and researchers about the existent quality cost models reveals a set of drawbacks (e.g. too theoretical and too close to ideal cases; too academic, with less practical impact; too much personalized to particular business processes, with difficulties in extrapolating to other cases; not comprising all dimensions of a business system. Using concepts and tools in quality management theory and practice and algorithms of innovative problem solving, this paper formulates a novel approach to improve practical usability, comprehensiveness, flexibility and customizability of a quality cost management system (QCMS when implementing it in a specific software application. Conclusions arising from the implementation in real industrial cases are also highlighted.

  11. A survey of pedagogical approaches and quality mechanisms used in education programs for mental health professionals.

    Science.gov (United States)

    McCann, Edward; Higgins, Agnes; Maguire, Gerry; Alexander, Jane; Watts, Mike; Creaner, Mary; Rani, Shobha

    2012-09-01

    The provision of high-quality education and training that is responsive, relevant, accessible and evidence based is critical if the vision for quality mental health services presented in recent policy initiatives in Ireland is to be fulfilled. This paper reports the findings related to pedagogical approaches and quality assurance mechanisms utilized within mental health education. The study involved canvassing all Higher Education Institutions in Ireland. A total of 227 courses in 31 educational institutes were identified and 149 questionnaires were returned from 129 Course Coordinators. Various quality processes were identified in existing programs; however, formal feedback from service providers, service users and carers was seldom reported. Ongoing evaluation and quality assurance strategies are a key element of governance and there is a need to develop strategies that explore the impact of education programs on mental health education and health outcomes. Recommendations are made in terms of future interprofessional mental health education and practice.

  12. Blind image quality assessment: a natural scene statistics approach in the DCT domain.

    Science.gov (United States)

    Saad, Michele A; Bovik, Alan C; Charrier, Christophe

    2012-08-01

    We develop an efficient, general-purpose, blind/noreference image quality assessment (NR-IQA) algorithm using a natural scene statistics (NSS) model of discrete cosine transform (DCT) coefficients. The algorithm is computationally appealing, given the availability of platforms optimized for DCT computation. The approach relies on a simple Bayesian inference model to predict image quality scores given certain extracted features. The features are based on an NSS model of the image DCT coefficients. The estimated parameters of the model are utilized to form features that are indicative of perceptual quality. These features are used in a simple Bayesian inference approach to predict quality scores. The resulting algorithm, which we name BLIINDS-II, requires minimal training and adopts a simple probabilistic model for score prediction. Given the extracted features from a test image, the quality score that maximizes the probability of the empirically determined inference model is chosen as the predicted quality score of that image. When tested on the LIVE IQA database, BLIINDS-II is shown to correlate highly with human judgments of quality, at a level that is competitive with the popular SSIM index.

  13. Integration of environmental approaches to strategy of production enterprises - environmentally oriented quality of production

    Directory of Open Access Journals (Sweden)

    Michalíková Františka

    2001-12-01

    Full Text Available In the paper there are presented system approaches, applied in Slovak transformed production enterprises, which solve questions of closing the so called industrial cycle from the side of the wastes' producers. The production quality is connected not only with the technological chain itself and with outputs from it - the utility product, but also with the load of the life environment.The presented possibilities of the liquidation of solid energetic waste – fly ashes – represent a an overview of forms and methods of its utilization. By combusting one kind of coal in various boilers, fly ashes with different physical, chemical, and mineralogical properties originate, with the combustion temperature as a dominant factor. The fly ashes are directly (without influencing its composition applied in civil engineering, mining, metallurgy, waste water cleaning, etc. Their utilization after a separation removal of unwanted components is an economically difficult process. Such a unvaluable component is coal combustion residue, evaluated by the annealing loss (carbon-in-ash loss in fly ashes used for special procedures in civil enginering, e.g. in mortars (maximally 4% of c.a.s. loss or in the porous concrete (4-7% of c.a.s. loss. The building industry processes about 20% of solid energetic waste.

  14. Factors of Quality Improvement of the Foreign Language Teaching in Technical University

    Directory of Open Access Journals (Sweden)

    Ira R. Agasieva

    2017-03-01

    Full Text Available In the article the problem of quality of teaching and knowledge of the English language has been considered. The factors that influence the improvement of the quality of teaching and knowledge of the English language in a technical college, the use of various methods of enhancing the quality of teaching and knowledge of the English language has been analyzed. It has been distinguished the necessity of taking into account the factors such as emotional maturity of the student, the desire for success, student cognitive style, its consistency and independence.

  15. Quality of life and its related factors in infertile couples.

    Science.gov (United States)

    Keramat, Afsaneh; Masoomi, Seyyedeh Zahra; Mousavi, Seyed Abbas; Poorolajal, Jalal; Shobeiri, Fatemeh; Hazavhei, Seyyed Mohammad Mehdi

    2014-01-01

    Health related quality of life (QoL) has now been considered as a main tool for outcome measurement in infertility. The present study aimed to determine the association between general and specified QoL with different psychological aspects of self-esteem, social support, sexual satisfaction, and marital satisfaction in a sample of Iranian infertile couples. This cross-sectional study was conducted on 385 infertile couples referred to the Fatemieh Hospital in Hamadan City, western Iran in 2012.To measure the self-esteem, the Iseng test was used. The social support scaling developed by Cassidy and Long was used for assessment of social support. The sexual satisfaction was also assessed by the Lindaberg questionnaire. For assessing the general QoL state, the WHO-QoL-BREF and FertiQoL tools were employed. Self-esteem scores were lower in the couples with longer infertility duration. The social support mean score was lower in low income couples. Those with higher educational level, shorter infertility duration, and higher income were more satisfied from their marital relationships. Besides, we revealed that the previous failed efforts for treatment of infertility were adversely associated with the lower social support and sexual satisfaction. The higher educational level, higher monthly income, living in urban area, shorter duration of marriage and infertility, and male gender were associated with better. QoL status in the most components.Associations between QoL and self-esteem, social support, sexual satisfaction, and marital satisfaction were significant (Pself-esteem, social support, sexual satisfaction, and marital satisfaction.

  16. [Improvement approaches in the hospital setting: From total quality management to Lean].

    Science.gov (United States)

    Curatolo, N; Lamouri, S; Huet, J-C; Rieutord, A

    2015-07-01

    Hospitals have to deal strong with economic constraints and increasing requirements in terms of quality and safety of care. To address these constraints, one solution could be the adoption of approaches from the industry sector. Following the decree of April 6, 2011 on the quality management of the medication use process, some of these approaches, such as risk management, are now part of the everyday work of healthcare professionals. However, other approaches, such as business process improvement, are still poorly developed in the hospital setting. In this general review, we discuss the main approaches of business process improvements that have been used in hospitals by focusing specifically on one of the newest and most currently used: Lean.

  17. Lessons learned from different approaches towards classifying personal factors.

    Science.gov (United States)

    Müller, Rachel; Geyh, Szilvia

    2015-01-01

    To examine and compare existing suggestions towards a classification of Personal Factors (PF) of the International Classification of Functioning, Disability and Health (ICF). Qualitative and quantitative content analyses of available categorizations of PF are conducted. While the eight categorizations greatly differ in their background and structure, the broad content areas covered seem to be similar and reflect the ICF definition of PF. They cover to various degrees 12 broad content areas: socio-demographic factors, behavioral and lifestyle factors, cognitive psychological factors, social relationships, experiences and biography, coping, emotional factors, satisfaction, other health conditions, biological/physiological factors, personality, motives/motivation. In comparing these categorizations, a common core of content issues for a potential ICF PF classification could be identified and valuable lessons learned. This can contribute to future classification development activities in relation to PF.

  18. Assessment of Near-Bottom Water Quality of Southwestern Coast of Sarawak, Borneo, Malaysia: A Multivariate Statistical Approach

    Directory of Open Access Journals (Sweden)

    Chen-Lin Soo

    2017-01-01

    Full Text Available The study on Sarawak coastal water quality is scarce, not to mention the application of the multivariate statistical approach to investigate the spatial variation of water quality and to identify the pollution source in Sarawak coastal water. Hence, the present study aimed to evaluate the spatial variation of water quality along the coastline of the southwestern region of Sarawak using multivariate statistical techniques. Seventeen physicochemical parameters were measured at 11 stations along the coastline with approximately 225 km length. The coastal water quality showed spatial heterogeneity where the cluster analysis grouped the 11 stations into four different clusters. Deterioration in coastal water quality has been observed in different regions of Sarawak corresponding to land use patterns in the region. Nevertheless, nitrate-nitrogen exceeded the guideline value at all sampling stations along the coastline. The principal component analysis (PCA has determined a reduced number of five principal components that explained 89.0% of the data set variance. The first PC indicated that the nutrients were the dominant polluting factors, which is attributed to the domestic, agricultural, and aquaculture activities, followed by the suspended solids in the second PC which are related to the logging activities.

  19. Evaluating risk factor assumptions: a simulation-based approach

    Directory of Open Access Journals (Sweden)

    Miglioretti Diana L

    2011-09-01

    Full Text Available Abstract Background Microsimulation models are an important tool for estimating the comparative effectiveness of interventions through prediction of individual-level disease outcomes for a hypothetical population. To estimate the effectiveness of interventions targeted toward high risk groups, the mechanism by which risk factors influence the natural history of disease must be specified. We propose a method for evaluating these risk factor assumptions as part of model-building. Methods We used simulation studies to examine the impact of risk factor assumptions on the relative rate (RR of colorectal cancer (CRC incidence and mortality for a cohort with a risk factor compared to a cohort without the risk factor using an extension of the CRC-SPIN model for colorectal cancer. We also compared the impact of changing age at initiation of screening colonoscopy for different risk mechanisms. Results Across CRC-specific risk factor mechanisms, the RR of CRC incidence and mortality decreased (towards one with increasing age. The rate of change in RRs across age groups depended on both the risk factor mechanism and the strength of the risk factor effect. Increased non-CRC mortality attenuated the effect of CRC-specific risk factors on the RR of CRC when both were present. For each risk factor mechanism, earlier initiation of screening resulted in more life years gained, though the magnitude of life years gained varied across risk mechanisms. Conclusions Simulation studies can provide insight into both the effect of risk factor assumptions on model predictions and the type of data needed to calibrate risk factor models.

  20. Approaches to ensuring and improving quality in the context of health system strengthening: a cross-site analysis of the five African Health Initiative Partnership programs.

    Science.gov (United States)

    Hirschhorn, Lisa R; Baynes, Colin; Sherr, Kenneth; Chintu, Namwinga; Awoonor-Williams, John Koku; Finnegan, Karen; Philips, James F; Anatole, Manzi; Bawah, Ayaga A; Basinga, Paulin

    2013-01-01

    Integrated into the work in health systems strengthening (HSS) is a growing focus on the importance of ensuring quality of the services delivered and systems which support them. Understanding how to define and measure quality in the different key World Health Organization building blocks is critical to providing the information needed to address gaps and identify models for replication. We describe the approaches to defining and improving quality across the five country programs funded through the Doris Duke Charitable Foundation African Health Initiative. While each program has independently developed and implemented country-specific approaches to strengthening health systems, they all included quality of services and systems as a core principle. We describe the differences and similarities across the programs in defining and improving quality as an embedded process essential for HSS to achieve the goal of improved population health. The programs measured quality across most or all of the six WHO building blocks, with specific areas of overlap in improving quality falling into four main categories: 1) defining and measuring quality; 2) ensuring data quality, and building capacity for data use for decision making and response to quality measurements; 3) strengthened supportive supervision and/or mentoring; and 4) operational research to understand the factors associated with observed variation in quality. Learning the value and challenges of these approaches to measuring and improving quality across the key components of HSS as the projects continue their work will help inform similar efforts both now and in the future to ensure quality across the critical components of a health system and the impact on population health.

  1. Influence of stress factors and socio-demographic characteristics on the sleep quality of nursing students

    Directory of Open Access Journals (Sweden)

    Sonia Betzabeth Ticona Benavente

    2014-06-01

    Full Text Available Objective:To analyze the influence of stress factors and socio-demographic characteristics on the sleep quality of nursing students. Method: An analytical cross-sectional and quantitative study, conducted with 151 nursing students in São Paulo between March and April of 2012. A form for socio-demographic characteristics, the Instrument to Evaluate Stress in Nursing Students and the Pittsburgh Sleep Index were applied. Results: High levels of stress was predominant for Time Management (27.8% and Professional Training (30.5% and low sleep quality (78.8%. The Professional Communication, Professional Training and Theoretical Activity are positively correlated to sleep quality. Work activity, academic year and time for daily studies contributed to a low quality of sleep. Conclusion: Few stress factors from the academic environment and some socio-demographic characteristics contributed to the reduction of sleep quality in students.

  2. Association between socioeconomic factors and sleep quality in an urban population-based sample in Germany

    DEFF Research Database (Denmark)

    Anders, Markus P; Breckenkamp, Jürgen; Blettner, Maria

    2014-01-01

    BACKGROUND: Good sleep quality is essential for recovery. The risk factors of sleep disorders have been extensively investigated, but there is sparse information on the association of socioeconomic factors with a person's sleep quality. The aim of the present analysis is to investigate...... from the baseline survey taken in 2004. Sleep quality for the same participants was measured with in-depth personal interviews in 2006 using the Pittsburgh Sleep Quality Index, together with other relevant characteristics (e.g. anxiety, depression and health status). Multiple logistic regression...... analyses were performed. RESULTS: People living in an urban environment with a high or medium SES have a greater probability of good sleep quality (odds ratio 1.65, 95% confidence interval 1.27-2.14; odds ratio 1.40, 95% confidence interval 1.16-1.69) than persons with a low SES. Anxiety and depression...

  3. Beam quality M 2 factor matrix for non-circular symmetric laser beams

    Science.gov (United States)

    Du, Yongzhao; Fu, Yuqing; Zheng, Chaoying

    2017-02-01

    It is standard to use Mx2 and My2 to characterize the beam quality of a non-circular symmetrical beam on its x-axis and y-axis orientation. However, we knew that the values of Mx2 and My2 are inconsistent if one selects a different coordinate system or measures beam quality with different experimental conditionals, even when analyzing the same beam. To overcome this, a new beam quality characterization method, the M 2 factor matrix, is developed. It not only contains the beam quality terms, Mx2 and My2 , to characterize the beam quality along x-axis and y-axis orientation for the non-symmetric beam, but also introduces two additional cross terms, M xy and M yx , which are used to characterize the location relationship between the principal axis of the test beam and coordinate system in experiment. Moreover, M 2 factor matrix can be measured with a similar procedure to the traditional M 2 factor whose measurement instructions are described in ISO11146 by adding some additional image and signal processing procedure. The measurement principle and method is present and the experiment system for beam quality M 2 factor matrix is built to demonstrate the performance of M 2 factor matrix with real experiments.

  4. Nanotube mechanical resonators with quality factors of up to 5 million

    Science.gov (United States)

    Moser, J.; Eichler, A.; Güttinger, J.; Dykman, M. I.; Bachtold, A.

    2014-12-01

    Carbon nanotube mechanical resonators have attracted considerable interest because of their small mass, the high quality of their surfaces, and the pristine electronic states they host. However, their small dimensions result in fragile vibrational states that are difficult to measure. Here, we observe quality factors Q as high as 5 × 106 in ultra-clean nanotube resonators at a cryostat temperature of 30 mK, where we define Q as the ratio of the resonant frequency over the linewidth. Measuring such high quality factors requires the use of an ultra-low-noise method to rapidly detect minuscule vibrations, as well as careful reduction of the noise of the electrostatic environment. We observe that the measured quality factors fluctuate because of fluctuations of the resonant frequency. We measure record-high quality factors, which are comparable to the highest Q values reported in mechanical resonators of much larger size, a remarkable result considering that reducing the size of resonators is usually concomitant with decreasing quality factors. The combination of ultra-low mass and very large Q offers new opportunities for ultra-sensitive detection schemes and quantum optomechanical experiments.

  5. Planar ring-shaped phononic crystal anchoring boundaries for enhancing the quality factor of Lamb mode resonators

    Science.gov (United States)

    Binci, L.; Tu, C.; Zhu, H.; Lee, J. E.-Y.

    2016-11-01

    We report the use of planar ring-shaped phononic crystals (PnCs) as anchor boundaries of very-high-frequency band piezoelectric-on-silicon Lamb mode resonators for the purpose of enhancing their quality factor (Q). Here, we exploit the acoustic bandgap associated with the PnC anchoring boundaries to reduce acoustic energy leakage out of the micromechanical resonator. The proposed approach provides greater mechanical robustness (by merit of interlocking the cells in a matrix) and the possibility of electrical routing through the PnC cells. We experimentally show enhancements in Q by a factor of three using the proposed approach of hybridizing planar ring-shaped PnCs with micromechanical resonators. The effect of these PnCs on resonator Q is further corroborated by their effects in suppressing transmission when incorporated into a delay line.

  6. Not So Fast: Inflation in Impact Factors Contributes to Apparent Improvements in Journal Quality

    Science.gov (United States)

    Neff, Bryan D.; Olden, Julian D.

    2010-01-01

    The Institute for Scientific Information (ISI) impact factor has become an important standard for assessing journal quality. Here we propose that impact factors may be subject to inflation analogous to changes in monetary prices in economics. The possibility of inflation came to light as a result of the observation that papers published today tend…

  7. Association between socioeconomic factors and sleep quality in an urban population-based sample in Germany.

    Science.gov (United States)

    Anders, Markus P; Breckenkamp, Jürgen; Blettner, Maria; Schlehofer, Brigitte; Berg-Beckhoff, Gabriele

    2014-12-01

    Good sleep quality is essential for recovery. The risk factors of sleep disorders have been extensively investigated, but there is sparse information on the association of socioeconomic factors with a person's sleep quality. The aim of the present analysis is to investigate this association, taking particularly the effect of health confounders into consideration. The data were extracted from the cross-sectional QUEBEB Study. In total, the study sample consisted of 3281 participants (1817 women and 1464 men, aged 16-72 years). Here socioeconomic status (SES) was collected from the baseline survey taken in 2004. Sleep quality for the same participants was measured with in-depth personal interviews in 2006 using the Pittsburgh Sleep Quality Index, together with other relevant characteristics (e.g. anxiety, depression and health status). Multiple logistic regression analyses were performed. People living in an urban environment with a high or medium SES have a greater probability of good sleep quality (odds ratio 1.65, 95% confidence interval 1.27-2.14; odds ratio 1.40, 95% confidence interval 1.16-1.69) than persons with a low SES. Anxiety and depression, but also health status, are also associated with sleep quality and can influence in part the socioeconomic levels seen in sleep quality. SES and sleep quality are associated. However, there are important additional determinants that influence the level of association between SES and sleep quality. Several factors, such as anxiety, depression and health status, are associated with poorer sleep quality, but at the same time, these factors occur more often within lower social classes. © The Author 2013. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved.

  8. THE QUALITY OF HUMAN RESOURCES – A REQUEST FOR HOTEL INDUSTRY DEVELOPMENT. A THEORETICAL APPROACH

    Directory of Open Access Journals (Sweden)

    Aruștei Carmen Claudia

    2013-04-01

    Full Text Available In this article we focus on the importance of human resource quality from hotel industry in obtaining quality services and further more in obtaining hotel industry development. We address this issue due to the fact that, usually, when talking about tourism or hotel industry development, the literature in the field offers macro solutions like, infrastructure development, service/product development and/or improving service quality. We consider that a micro approach is also important and from this perspective, we emphasis the role of human resource quality for industry development. The quality of human resources, as a dimension of service quality was not detailed extensively by the literature in the field but we found it relevant for hotel industry development, as this industry it is a service industry, and as Ritz-Carlton Company’s motto say “service comes only from people”. In this article we focus on the importance of human resource quality from hotel industry in obtaining quality services and further more in obtaining hotel industry development. We address this issue due to the fact that, usually, when talking about tourism or hotel industry development, the literature in the field offers macro solutions like, infrastructure development, service/product development and/or improving service quality. We consider that a micro approach is also important and from this perspective, we emphasis the role of human resource quality for industry development. The quality of human resources, as a dimension of service quality was not detailed extensively by the literature in the field but we found it relevant for hotel industry development, as this industry it is a service industry, and as Ritz-Carlton Company’s motto say “service comes only from people”. In this article we focus on the importance of human resource quality from hotel industry in obtaining quality services and further more in obtaining hotel industry development. We address this

  9. Design of psychosocial factors questionnaires: a systematic measurement approach.

    Science.gov (United States)

    Villalobos, Gloria H; Vargas, Angélica M; Rondón, Martin A; Felknor, Sarah A

    2013-01-01

    Evaluation of psychosocial factors requires instruments that measure dynamic complexities. This study explains the design of a set of questionnaires to evaluate work and non-work psychosocial risk factors for stress-related illnesses. The measurement model was based on a review of literature. Content validity was performed by experts and cognitive interviews. Pilot testing was carried out with a convenience sample of 132 workers. Cronbach's alpha evaluated internal consistency and concurrent validity was estimated by Spearman correlation coefficients. Three questionnaires were constructed to evaluate exposure to work and non-work risk factors. Content validity improved the questionnaires coherence with the measurement model. Internal consistency was adequate (α = 0.85-0.95). Concurrent validity resulted in moderate correlations of psychosocial factors with stress symptoms. Questionnaires' content reflected a wide spectrum of psychosocial factors sources. Cognitive interviews improved understanding of questions and dimensions. The structure of the measurement model was confirmed. Copyright © 2012 Wiley Periodicals, Inc.

  10. Assessing the Quality of Life in Elderly People and Related Factors in Tabriz, Iran

    Directory of Open Access Journals (Sweden)

    Yaser Khaje-Bishak

    2014-12-01

    Full Text Available Introduction: Elderly people may suffer from the multiple health disorders due to the vulnerability for many physical and mental disturbances. Quality of life in elderly population can be affected by many environmental factors. The aim of this study was aimed to examine the quality of life in elderly people in Tabriz, Iran in 2012. Methods: This cross-sectional study was carried out on 184 elderly people (male=97; female=87 with age ≥ 60 years. The participants surveyed in this study were elderly people who were living in the community and come voluntarily to the daily care centers. Validated Persian self-reported version of World Health Organization Quality of Life-BRIEF (WHOQOL-BRIEF questionnaire including 26 broad and comprehensive questions were used to determine the quality of life in elderly people. Independent t-test and Pearson correlation were used to compare differences and correlation between the total score of quality of life and influential factors. Results: Total score the quality of life in both genders was 90.75 (13.37 (range between 26-130. Male elderly had slightly high score in the quality of life; however, these differences were not significant. A significant difference was observed between having cardiovascular diseases, respiratory and gastrointestinal diseases, hearing and visual impairments with total score in the quality of life. Also, there was no significant difference between gender and age variables with total score in the quality of life. Conclusion: Policies and programs should be considered for improving the quality of life. Future studies are needed for assessing other influential factors on the quality of life in elderly population.

  11. Analytical Quality by Design Approach to Test Method Development and Validation in Drug Substance Manufacturing

    Directory of Open Access Journals (Sweden)

    N. V. V. S. S. Raman

    2015-01-01

    Full Text Available Pharmaceutical industry has been emerging rapidly for the last decade by focusing on product Quality, Safety, and Efficacy. Pharmaceutical firms increased the number of product development by using scientific tools such as QbD (Quality by Design and PAT (Process Analytical Technology. ICH guidelines Q8 to Q11 have discussed QbD implementation in API synthetic process and formulation development. ICH Q11 guidelines clearly discussed QbD approach for API synthesis with examples. Generic companies are implementing QbD approach in formulation development and even it is mandatory for USFDA perspective. As of now there is no specific requirements for AQbD (Analytical Quality by Design and PAT in analytical development from all regulatory agencies. In this review, authors have discussed the implementation of QbD and AQbD simultaneously for API synthetic process and analytical methods development. AQbD key tools are identification of ATP (Analytical Target Profile, CQA (Critical Quality Attributes with risk assessment, Method Optimization and Development with DoE, MODR (method operable design region, Control Strategy, AQbD Method Validation, and Continuous Method Monitoring (CMM. Simultaneous implementation of QbD activities in synthetic and analytical development will provide the highest quality product by minimizing the risks and even it is very good input for PAT approach.

  12. Application of Scientific Approaches for Evaluation of Quality of Learning Objects in eQNet Project

    Science.gov (United States)

    Kurilovas, Eugenijus; Serikoviene, Silvija

    The paper is aimed to analyse the application of several scientific approaches, methods, and principles for evaluation of quality of learning objects for Mathematics subject. The authors analyse the following approaches to minimise subjectivity level in expert evaluation of the quality of learning objects, namely: (1) principles of multiple criteria decision analysis for identification of quality criteria, (2) technological quality criteria classification principle, (3) fuzzy group decision making theory to obtain evaluation measures, (4) normalisation requirement for criteria weights, and (5) scalarisation method for learning objects quality optimisation. Another aim of the paper is to outline the central role of social tagging to describe usage, attention, and other aspects of the context; as well as to help to exploit context data towards making learning object repositories more useful, and thus enhance the reuse. The applied approaches have been used practically for evaluation of learning objects and metadata tagging while implementing European eQNet and te@ch.us projects in Lithuanian comprehensive schools in 2010.

  13. Quality by design approach for optimizing the formulation and physical properties of extemporaneously prepared orodispersible films

    NARCIS (Netherlands)

    Visser, J. Caroline; Dohmen, Willem M. C.; Hinrichs, Wouter L. J.; Breitkreutz, Joerg; Frijlink, Henderik W.; Woerdenbag, Herman J.

    2015-01-01

    The quality by design (QbD) approach was applied for optimizing the formulation of extemporaneously prepared orodispersible films (ODFs) using Design-Expert Software. The starting formulation was based on earlier experiments and contained the film forming agents hypromellose and carbomer 974P and th

  14. Exercising Quality Control in Interdisciplinary Education: Toward an Epistemologically Responsible Approach

    Science.gov (United States)

    Stein, Zachary; Connell, Michael; Gardner, Howard

    2008-01-01

    This article argues that certain philosophically devised quality control parameters should guide approaches to interdisciplinary education. We sketch the kind of reflections we think are necessary in order to produce epistemologically responsible curricula. We suggest that the two overarching epistemic dimensions of levels of analysis and basic…

  15. Antecedents and Consequences of Service Quality in a Higher Education Context: A Qualitative Research Approach

    Science.gov (United States)

    Sultan, Parves; Wong, Ho Yin

    2013-01-01

    Purpose: The purpose of the paper is to report on the perception of students in regard to critical antecedents, dimensions and consequences of service quality with an aim to develop a theoretical model in the context of a university in Australia. Design/methodology/approach: This research used focus group discussions with 19 students who had been…

  16. Unmasking the Teaching Quality of Higher Education: Students' Course Experience and Approaches to Learning in China

    Science.gov (United States)

    Yin, Hongbiao; Lu, Genshu; Wang, Wenyan

    2014-01-01

    The quality of teaching in higher education is a topic which has generated heated debate in China, though there has been a remarkable paucity of empirical research into the characteristics of teaching and learning in Chinese universities. This study examined Chinese university students' course experience and its influence on their approaches to…

  17. Education Quality in Kazakhstan in the Context of Competence-Based Approach

    Science.gov (United States)

    Nabi, Yskak; Zhaxylykova, Nuriya Ermuhametovna; Kenbaeva, Gulmira Kaparbaevna; Tolbayev, Abdikerim; Bekbaeva, Zeinep Nusipovna

    2016-01-01

    The background of this paper is to present how education system of Kazakhstan evolved during the last 24 years of independence, highlighting the contemporary transformational processes. We defined the aim to identify the education quality in the context of competence-based approach. Methods: Analysis of references, interviewing, experimental work.…

  18. User involvement in measuring service quality of local authority occupational therapy services: a new approach.

    NARCIS (Netherlands)

    Sixma, H.J.; Calnan, S.; Calnan, M.; Groenewegen, P.P.

    2001-01-01

    The aim of this paper is two-fold: (i) to describe the development of a new measuring instrument for quality of care from the perspective of the users of local authority Occupational Therapy (OT) services, and (ii) to evaluate the potential of the new instrument as a standardized approach for the

  19. Translating Quality in Higher Education: US Approaches to Accreditation of Institutions from around the World

    Science.gov (United States)

    Blanco Ramírez, Gerardo

    2015-01-01

    This article reports on findings from a sociolinguistic qualitative study exploring inter-discursive relations manifested in the approaches and strategies that regional accrediting agencies in the United States utilise when recognising foreign universities. Even as most countries have developed national quality assurance systems and whilst…

  20. Antecedents and Consequences of Service Quality in a Higher Education Context: A Qualitative Research Approach

    Science.gov (United States)

    Sultan, Parves; Wong, Ho Yin

    2013-01-01

    Purpose: The purpose of the paper is to report on the perception of students in regard to critical antecedents, dimensions and consequences of service quality with an aim to develop a theoretical model in the context of a university in Australia. Design/methodology/approach: This research used focus group discussions with 19 students who had been…

  1. New approaches for identification factors of cost management

    Directory of Open Access Journals (Sweden)

    Kholkin Anatolii

    2017-01-01

    Full Text Available This article deals with determination and classification factors, that affect the costs and whose changes are result of management decisions. The modern condition of scientific researches in this field of economic science is analyzed. The classification of impact factors is made for machine building industry. Also is given new costs classification according to impact factors. New cost classification includes three classes and eighteen groups of cost. Every class and group is described. The need of this classification for purposes of cost management is defined. Also the practical significance from the use of new costs classification in management decisions and control is described

  2. The DPSIR Framework and a Pressure-Oriented Water Quality Monitoring Approach to Ecological River Restoration

    Directory of Open Access Journals (Sweden)

    Björn Frostell

    2012-09-01

    Full Text Available Without monitoring anthropogenic pressures on the water environment, it is difficult to set realistic river restoration targets in relation to water quality. Therefore a more holistic approach is needed to systematically explore the links between socio-economic drivers and observed water quality-related impacts on river ecosystems. Using the DPSIR (Drivers-Pressures-State of the Environment-Impacts-Responses framework, this study linked ecological river restoration with the socio-economic sector, with the focus on promoting a pressure-oriented water quality monitoring system. Based on the European Water Framework Directive (WFD and relevant literature, it was found that most water quality-related indicators employed today are state/impacts-oriented, while very few are pressure-oriented. As a response, we call for more attention to a DPR (Drivers-Pressures-Responses framework in developing an industrial ecology-based pressure-oriented water quality monitoring system for aiding ecological river restoration planning. This approach is characterized in general by accounting for material-related flows throughout the socio-economic sector in relation to river ecosystem degradation. Then the obtained information would help decision makers take appropriate measures to alleviate various significant human-induced wastes and emissions at their sources. We believe that such a pressure-oriented monitoring system will substantially complement traditional state/impacts-oriented environmental and ecological monitoring and help develop more proactive planning and decision-making processes for specific river restoration projects and general water quality management.

  3. Sleep quality and some factors affecting sleep quality in the students living in the residence hall of a university

    Directory of Open Access Journals (Sweden)

    Ozge Yavuz Sari

    2015-04-01

    Full Text Available AIM: Sleep disorders are remarkable public health problems as they adversely affect physical, mental and social health and may cause accidents and decline in academic performance and labor productivity. Aim of the study is assessing sleep quality and determining some factors affecting sleep quality in the students living in the residence hall of a university. METHOD: It is a cross sectional study conducted with 277 students, 180 of whom are female. Data were collected via a questionnaire including Pittsburgh Sleep Quality Index (PSQI, Epworth Sleepiness Scale (ESS and socio-demographic characteristics query. RESULTS: According to PSQI, 41.1% of students have bad sleep quality. Sleep quality of male students and students who are overweight/obese or living in more crowded rooms in the hall of residence is worse than other students and #8217;. Prevalence of bad sleep quality is higher in medication users, participants thinking that they have problems in sleeping or falling asleep and had stressful experience in the last month. The differences between groups were statistically significant. In logistic regression analyzes, using medication (OR=2.54, having problems in sleep (OR=12.75, having problems in falling asleep (OR=8.83 and bad experiences in the last month (OR=2.66 have effects on sleep quality. CONCLUSIONS: Interventions about sleep disorders are important due to their preventable characteristics. Developing healthy life habits, improving physical conditions and coping with stress will be effective on preventing and treating sleep disorders. [TAF Prev Med Bull 2015; 14(2.000: 93-100

  4. Design of video quality metrics with multi-way data analysis a data driven approach

    CERN Document Server

    Keimel, Christian

    2016-01-01

    This book proposes a data-driven methodology using multi-way data analysis for the design of video-quality metrics. It also enables video- quality metrics to be created using arbitrary features. This data- driven design approach not only requires no detailed knowledge of the human visual system, but also allows a proper consideration of the temporal nature of video using a three-way prediction model, corresponding to the three-way structure of video. Using two simple example metrics, the author demonstrates not only that this purely data- driven approach outperforms state-of-the-art video-quality metrics, which are often optimized for specific properties of the human visual system, but also that multi-way data analysis methods outperform the combination of two-way data analysis methods and temporal pooling. .

  5. Factual Approach in Decision Making - the Prerequisite of Success in Quality Management

    Science.gov (United States)

    Kučerová, Marta; Škůrková Lestyánszka, Katarína

    2013-12-01

    In quality management system as well as in other managerial systems, effective decisions must be always based on the data and information analysis, i.e. based on facts, in accordance with the factual approach principle in quality management. It is therefore necessary to measure and collect the data and information about processes. The article presents the results of a conducted survey, which was focused on application of factual approach in decision making. It also offers suggestions for improvements of application of the principle in business practice. This article was prepared using the research results of VEGA project No. 1/0229/08 "Perspectives of the quality management development in relation to the requirements of market in the Slovak Republic".

  6. Algebraic approach to form factors in the complex sinh-Gordon theory

    CERN Document Server

    Lashkevich, Michael

    2016-01-01

    We study form factors of the quantum complex sinh-Gordon theory in the algebraic approach. In the case of exponential fields the form factors can be obtained from the known form factors of the $Z_N$-symmetric Ising model. The algebraic construction also provides an Ansatz for form factors of descendant operators. We obtain generating functions of such form factors and establish their main properties: the cluster factorization and reflection equations.

  7. Algebraic approach to form factors in the complex sinh-Gordon theory

    Science.gov (United States)

    Lashkevich, Michael; Pugai, Yaroslav

    2017-01-01

    We study form factors of the quantum complex sinh-Gordon theory in the algebraic approach. In the case of exponential fields the form factors can be obtained from the known form factors of the ZN-symmetric Ising model. The algebraic construction also provides an Ansatz for form factors of descendant operators. We obtain generating functions of such form factors and establish their main properties: the cluster factorization and reflection equations.

  8. Air quality perception of pedestrians in an urban outdoor Mediterranean environment: A field survey approach.

    Science.gov (United States)

    Pantavou, Katerina; Lykoudis, Spyridon; Psiloglou, Basil

    2017-01-01

    Perception plays a significant role on people's response to preventive measures. In the view of public awareness, the aim of this study was to explore factors that affect air quality perception and to reveal its potential patterns. Air quality perception of individuals, in terms of dust and overall air quality, was examined in relation to air pollutants concentrations, meteorological variables, personal characteristics as well as their thermal sensation and health condition. The data used were obtained from environmental measurements, in situ and from stations, and questionnaire surveys conducted in an outdoor urban Mediterranean area, Athens, Greece. The participants were asked to report their air quality perception and thermal sensation based on predefined scales. A thermal index, Physiological Equivalent Temperature (PET), was estimated to obtain an objective measure of thermal sensation. Particulate matter (PM10) and nitrogen oxide (NO) were associated with dust perception. Nitrogen oxides (NOx) and carbon monoxide (CO) were associated to air quality perception. Age, area of residence, health symptoms and thermal sensation also affected the perception of air quality. Dusty or poor air quality conditions were more likely to be reported when pollutants' concentrations were increased. Younger people, participants residing in the city center, experiencing health symptoms or warm thermal sensation showed a trend towards reporting more unfavorable air quality conditions. Copyright © 2016 Elsevier B.V. All rights reserved.

  9. Electromagnetic form factors of baryons in an algebraic approach

    Energy Technology Data Exchange (ETDEWEB)

    Bijker, R. [Instituto de Ciencias Nucleares, Universidad Nacional Autonoma de Mexico, Apartado Postal 70-543, 04510 Mexico D.F. (Mexico); Leviatan, A. [Racah Institute of Physics, The Hebrew University, Jerusalem 91904 (Israel)

    1999-07-01

    We present a simultaneous analysis of elastic and transition form factors of the nucleon. The calculations are performed in the framework of an algebraic model of baryons. Effects of meson cloud couplings are considered. (Author)

  10. Electromagnetic form factors of baryons in an algebraic approach

    CERN Document Server

    Bijker, R

    1999-01-01

    We present a simultaneous analysis of elastic and transition form factors of the nucleon. The calculations are performed in the framework of an algebraic model of baryons. Effects of meson cloud couplings are considered.

  11. Globalization and Income Distribution: A Specific Factors Continuum Approach

    OpenAIRE

    Anderson, James E.

    2009-01-01

    Does globalization widen inequality or increase income risk? In the specific factors continuum model of this paper, globalization widens inequality, amplifying the positive (negative) premia for export (import- competing) sectors. Globalization amplifies the risk from idiosyncratic relative productivity shocks but reduces risk from aggregate shocks to absolute advantage, relative endowments and transfers. Aggregate-shock-induced income risk bears most heavily on the poorest specific factors, ...

  12. Factors Affecting Quality of Life and Fatigue in Gynaecologic Cancer Patients

    Directory of Open Access Journals (Sweden)

    Güngör İ

    2017-06-01

    Full Text Available Background: Cancer-related fatigue (CRF is the most commonly reported and most distressing symptom in cancer patients. Health-related quality of life (QOL is an important outcome in cancer management, the authors sought to better understand its determinants. Aim: This study aims to identify quality of life and fatigue levels and the affecting factors in gynaecologic cancer patients. Method: This descriptive and cross-sectional study was conducted with 154 volunteer women with gynaecologic cancer. The data were collected through the interview form, functional assessment of cancer therapy-general (FACT-G Quality of Life Scale, and Piper Fatigue Scale. Results: The mean score of total quality of life in gynaecologic cancer patients was low, 53.4 ± 15.4. Physical and emotional states were found to be the mostly affected states in the quality of life. According to the Piper Fatigue Scale, the total fatigue score was mild, 3.5 ± 2.4. Total fatigue scores were found to be high in metastatic cancers. Multivariate analyses indicate that the most important factor affecting the quality of life is economic condition, and the most important variables affecting fatigue are the level of activity and use of medicine. Conclusion: This study found that quality of life dimensions in women with gynaecologic cancer was affected by factors such as cancer type, time of diagnosis, and stage and spread of the cancer.

  13. What Factors Influence States' Capacity to Report Children's Health Care Quality Measures? A Multiple-Case Study.

    Science.gov (United States)

    Christensen, Anna L; Petersen, Dana M; Burton, Rachel A; Forsberg, Vanessa C; Devers, Kelly J

    2017-01-01

    Objectives The objective of this study was to describe factors that influence the ability of state Medicaid agencies to report the Centers for Medicare & Medicaid Services' (CMS) core set of children's health care quality measures (Child Core Set). Methods We conducted a multiple-case study of four high-performing states participating in the Children's Health Insurance Program Reauthorization Act (CHIPRA) Quality Demonstration Grant Program: Illinois, Maine, Pennsylvania, and Oregon. Cases were purposively selected for their diverse measurement approaches and used data from 2010 to 2015, including 154 interviews, semiannual grant progress reports, and annual public reports on Child Core Set measures. We followed Yin's multiple-case study methodology to describe how and why each state increased the number of measures reported to CMS. Results All four states increased the number of Child Core Set measures reported to CMS during the grant period. Each took a different approach to reporting, depending on the available technical, organizational, and behavioral inputs in the state. Reporting capacity was influenced by a state's Medicaid data availability, ability to link to other state data systems, past experience with quality measurement, staff time and technical expertise, and demand for the measures. These factors were enhanced by CHIPRA Quality Demonstration grant funding and other federal capacity building activities, as hypothesized in our conceptual framework. These and other states have made progress reporting the Child Core Set since 2010. Conclusion With financial support and investment in state data systems and organizational factors, states can overcome challenges to reporting most of the Child Core Set measures.

  14. The impact of psychological and clinical factors on quality of life in individuals with atopic dermatitis.

    Science.gov (United States)

    Wittkowski, Anja; Richards, Helen L; Griffiths, Christopher E M; Main, Chris J

    2004-08-01

    The aim of the study was to assess the influence of general and dermatitis-specific psychological and clinical factors on quality of life in adults with atopic dermatitis (AD). A total of 125 adults recruited through the National Eczema Society of U.K. (NES) completed a number of psychological and dermatological questionnaires, including the Dermatology Life Quality Index (DLQI), the Stigmatisation and Eczema Questionnaire (SEQ), the Hospital Anxiety and Depression Scale (HADS), the Fear of Negative Evaluation Scale (FNE) and the Rosenberg Self-Esteem Scale (RSE). Pearson's correlational analyses suggested that perceptions of stigma were significantly associated with psychological factors as well as quality of life (Ps<.01). An association was also found between perceived stigma and disease severity (-.28, P<.01). Almost 46% of participants were identified as having probable mood disorder. Regression analysis indicated that perceptions of stigma and depression accounted for 44.5% of the variance in quality of life in this sample [F(3,121)=34.18, P<.001], when disease severity was controlled for. Psychological factors and disease severity were strong predictors of quality of life in adults with AD. AD-related perceptions of stigma were of particular importance in predicting AD-related quality of life over and above more general psychological factors, such as depression. These findings have important implications for the psychological and clinical management of AD.

  15. COMPETITIVENESS AND QUALITY OF AGRIFOOD PRODUCTS - KEY FACTORS FOR THE SUCCESS OF EXPORT PROMOTION

    Directory of Open Access Journals (Sweden)

    Aurelia LITVIN

    2014-10-01

    Full Text Available Article reflects the competitiveness and quality management from the perspective of enunciated historical and methodological approaches. They are listed by management functions and show interrelation between quality and profit, thus addressing the economic entity as the core of acting for promotion of exports. Also, we set the calculation of indicators of competitiveness of agri-food exports from the Republic of Moldova and establish the priorities and the necessary conclusions.

  16. A kaizen approach to food safety quality management in the value chain from wheat to bread

    CERN Document Server

    Hill, Victoria

    2014-01-01

    This book provides a Management Science approach to quality management in food production. Aspects of food quality, product conformance and reliability/food safety are examined, starting with wheat and ending with its value chain transformation into bread. Protein qualities that influence glycemic index levels in bread are used to compare the value chains of France and the US. With Kaizen models the book shows how changes in these characteristics are the result of management decisions made by the wheat growers in response to government policy and industry strategy. Lastly, it provides step-by-step instructions on how to apply kaizen methodology and Deming's work on quality improvement to make the HACCPs (Hazard Analysis and Critical Control Points) in food safety systems more robust.

  17. Mobile 3D quality of experience evaluation: a hybrid data collection and analysis approach

    Science.gov (United States)

    Utriainen, Timo; Häyrynen, Jyrki; Jumisko-Pyykkö, Satu; Boev, Atanas; Gotchev, Atanas; Hannuksela, Miska M.

    2011-02-01

    The paper presents a hybrid approach to study the user's experienced quality of 3D visual content on mobile autostereoscopic displays. It combines extensive subjective tests with collection and objective analysis of eye-tracked data. 3D cues which are significant for mobiles are simulated in the generated 3D test content. The methodology for conducting subjective quality evaluation includes hybrid data-collection of quantitative quality preferences, qualitative impressions, and binocular eye-tracking. We present early results of the subjective tests along with eye movement reaction times, areas of interest and heatmaps obtained from raw eye-tracked data after statistical analysis. The study contributes to the question what is important to be visualized on portable auto-stereoscopic displays and how to maintain and visually enhance the quality of 3D content for such displays.

  18. Multi-criteria decision making approaches for quality control of genome-wide association studies.

    Science.gov (United States)

    Malovini, Alberto; Rognoni, Carla; Puca, Annibale; Bellazzi, Riccardo

    2009-03-01

    Experimental errors in the genotyping phases of a Genome-Wide Association Study (GWAS) can lead to false positive findings and to spurious associations. An appropriate quality control phase could minimize the effects of this kind of errors. Several filtering criteria can be used to perform quality control. Currently, no formal methods have been proposed for taking into account at the same time these criteria and the experimenter's preferences. In this paper we propose two strategies for setting appropriate genotyping rate thresholds for GWAS quality control. These two approaches are based on the Multi-Criteria Decision Making theory. We have applied our method on a real dataset composed by 734 individuals affected by Arterial Hypertension (AH) and 486 nonagenarians without history of AH. The proposed strategies appear to deal with GWAS quality control in a sound way, as they lead to rationalize and make explicit the experimenter's choices thus providing more reproducible results.

  19. Environmental Quality Assessment of Bizerte Lagoon (Tunisia) Using Living Foraminifera Assemblages and a Multiproxy Approach: e0137250

    National Research Council Canada - National Science Library

    Maria Virgínia Alves Martins; Noureddine Zaaboub; Lotfi Aleya; Fabrizio Frontalini; Egberto Pereira; Paulo Miranda; Miguel Mane; Fernando Rocha; Lazaro Laut; Monia El Bour

    2015-01-01

      This study investigated the environmental quality of the Bizerte Lagoon (Tunisia) through an integrated approach that combined environmental, biogeochemical, and living benthic foraminiferal analyses...

  20. Predictive and Prognostic Factors in Colorectal Cancer: A Personalized Approach

    Directory of Open Access Journals (Sweden)

    Timothy A. Rockall

    2011-03-01

    Full Text Available It is an exciting time for all those engaged in the treatment of colorectal cancer. The advent of new therapies presents the opportunity for a personalized approach to the patient. This approach considers the complex genetic mechanisms involved in tumorigenesis in addition to classical clinicopathological staging. The potential predictive and prognostic biomarkers which have stemmed from the study of the genetic basis of colorectal cancer and therapeutics are discussed with a focus on mismatch repair status, KRAS, BRAF, 18qLOH, CIMP and TGF-β.

  1. Identification and assessment of potential water quality impact factors for drinking-water reservoirs.

    Science.gov (United States)

    Gu, Qing; Deng, Jinsong; Wang, Ke; Lin, Yi; Li, Jun; Gan, Muye; Ma, Ligang; Hong, Yang

    2014-06-10

    Various reservoirs have been serving as the most important drinking water sources in Zhejiang Province, China, due to the uneven distribution of precipitation and severe river pollution. Unfortunately, rapid urbanization and industrialization have been continuously challenging the water quality of the drinking-water reservoirs. The identification and assessment of potential impacts is indispensable in water resource management and protection. This study investigates the drinking water reservoirs in Zhejiang Province to better understand the potential impact on water quality. Altogether seventy-three typical drinking reservoirs in Zhejiang Province encompassing various water storage levels were selected and evaluated. Using fifty-two reservoirs as training samples, the classification and regression tree (CART) method and sixteen comprehensive variables, including six sub-sets (land use, population, socio-economy, geographical features, inherent characteristics, and climate), were adopted to establish a decision-making model for identifying and assessing their potential impacts on drinking-water quality. The water quality class of the remaining twenty-one reservoirs was then predicted and tested based on the decision-making model, resulting in a water quality class attribution accuracy of 81.0%. Based on the decision rules and quantitative importance of the independent variables, industrial emissions was identified as the most important factor influencing the water quality of reservoirs; land use and human habitation also had a substantial impact on water quality. The results of this study provide insights into the factors impacting the water quality of reservoirs as well as basic information for protecting reservoir water resources.

  2. Psychosocial factors and health as determinants of quality of life in community-dwelling older adults.

    Science.gov (United States)

    Brett, Caroline E; Gow, Alan J; Corley, Janie; Pattie, Alison; Starr, John M; Deary, Ian J

    2012-04-01

    It is important to understand the determinants of differences in quality of life in old age and to include a wide range of possible predictors. The present study investigated the determinants of quality of life in two groups of older adults for whom there was an unusually informative set of possible predictor variables. Participants were members of the Lothian Birth Cohorts of 1921 (n = 550) or 1936 (n = 1,091). Four facets of quality of life (QoL) and general QoL were measured using the WHOQOL-BREF. Possible determinants included personality traits, measured with the International Personality Item Pool (IPIP) scales; childhood and old age general cognitive ability, measured with the Moray House Test; minor psychological symptoms, measured with the Hospital Anxiety and Depression Scale (HADS); physical health, assessed by grip strength and cardiovascular disease history; and sociodemographic factors, assessed by interview. Linear regression analyses revealed that HADS depression had the greatest influence on quality of life. Personality traits, most notably Emotional Stability, also predicted quality of life to varying degrees, along with factors reflecting current life circumstances. There were differences between the two cohorts in the variables which predicted quality of life. There were different, conceptually relevant, contributions to the different QoL facets. Personality traits and minor depressive symptoms have an important influence on self-reported quality of life in old age. Quality of life may be influenced more by current than past circumstances, and this relationship may change with age.

  3. Quality by design approach for development of suspension nasal spray products: a case study on budesonide nasal suspension.

    Science.gov (United States)

    Chudiwal, Swapnil Sharadkumar; Dehghan, Mohamed Hassan G

    2016-10-01

    The objective of this study was to provide quality by design (QbD) approach for development of suspension type nasal spray products. Quality target product profile (QTPP) of test product budesonide nasal suspension (B-NS) was defined and critical quality attributes (CQAs) were identified. Critical formulation, process and delivery device variables were recognized. Risk assessment was performed by using failure mode and effect analysis (FMEA) methodology. Selected variables were further assessed using a Plackett Burman screening study. A response surface design consisting of the critical factors was used to study the interactions between the study variables. Formulation variable X2: median particle size of budesonide (D50) (µ) has strikingly influenced dissolution (%) (Y1), while D50 droplet size distribution (µm) (Y2) was significantly impacted by formulation variable X1: Avicel RC 591 (%) and process variable X4: homogenization speed (rpm). A design space plot within which the CQAs remained unchanged was established at lab scale. A comprehensive approach for development of B-NS product based on the QbD methodology has been demonstrated. The accuracy and robustness of the model were confirmed by comparability of the predicted value generated by model with the observed value.

  4. Multivariate statistical approach for the assessment of groundwater quality in Ujjain City, India.

    Science.gov (United States)

    Vishwakarma, Vikas; Thakur, Lokendra Singh

    2012-10-01

    Groundwater quality assessment is an essential study which plays important role in the rational development and utilization of groundwater. Groundwater quality greatly influences the health of local people. The variations of water quality are essentially the combination of both anthropogenic and natural contributions. In order to understand the underlying physical and chemical processes this study analyzes 8 chemical and physical-chemical water quality parameters, viz. pH, turbidity, electrical conductivity, total dissolved solids, total alkalinity, total hardness, chloride and fluoride recorded at the 54 sampling stations during summer season of 2011 by using multivariate statistical techniques. Hierarchical clustering analysis (CA) is first applied to distinguish groundwater quality patterns among the stations, followed by the use of principle component analysis (PCA) and factor analysis (FA) to extract and recognize the major underlying factors contributing to the variations among the water quality measures. The first three components were chosen for interpretation of the data, which accounts for 72.502% of the total variance in the data set. The maximum number of variables, i.e. turbidity, EC, TDS and chloride were characterized by first component, while second and third were characterized by total alkalinity, total hardness, fluoride and pH respectively. This shows that hydro chemical constituents of the groundwater are mainly controlled by EC, TDS, and fluoride. The findings of the cluster analysis are presented in the form of dendrogram of the sampling stations (cases) as well as hydro chemical variables, which produced four major groupings, suggest that groundwater monitoring can be consolidated.

  5. Design of psychosocial factors questionnaires: a systematic measurement approach

    Science.gov (United States)

    Vargas, Angélica; Felknor, Sarah A

    2012-01-01

    Background Evaluation of psychosocial factors requires instruments that measure dynamic complexities. This study explains the design of a set of questionnaires to evaluate work and non-work psychosocial risk factors for stress-related illnesses. Methods The measurement model was based on a review of literature. Content validity was performed by experts and cognitive interviews. Pilot testing was carried out with a convenience sample of 132 workers. Cronbach’s alpha evaluated internal consistency and concurrent validity was estimated by Spearman correlation coefficients. Results Three questionnaires were constructed to evaluate exposure to work and non-work risk factors. Content validity improved the questionnaires coherence with the measurement model. Internal consistency was adequate (α=0.85–0.95). Concurrent validity resulted in moderate correlations of psychosocial factors with stress symptoms. Conclusions Questionnaires´ content reflected a wide spectrum of psychosocial factors sources. Cognitive interviews improved understanding of questions and dimensions. The structure of the measurement model was confirmed. PMID:22628068

  6. A combined structural dynamics approach identifies a putative switch in factor VIIa employed by tissue factor to initiate blood coagulation

    DEFF Research Database (Denmark)

    Olsen, Ole H; Rand, Kasper D; Østergaard, Henrik;

    2007-01-01

    Coagulation factor VIIa (FVIIa) requires tissue factor (TF) to attain full catalytic competency and to initiate blood coagulation. In this study, the mechanism by which TF allosterically activates FVIIa is investigated by a structural dynamics approach that combines molecular dynamics (MD...

  7. Burnout, quality of life, motivation, and academic achievement among medical students: A person-oriented approach.

    Science.gov (United States)

    Lyndon, Mataroria P; Henning, Marcus A; Alyami, Hussain; Krishna, Sanjeev; Zeng, Irene; Yu, Tzu-Chieh; Hill, Andrew G

    2017-04-01

    The aim of this study was to identify burnout and quality of life profiles of medical students and determine their associations with academic motivation and achievement on progress tests using a person-oriented approach. Medical students (n = 670) in Year 3 to Year 5 at the University of Auckland were classified into three different profiles as derived from a two-step cluster analysis using World Health Organization Quality of Life-BREF scores and Copenhagen Burnout Inventory scores. The profiles were used as independent variables to assess differences in academic motivation and achievement on progress tests using a multivariate analysis of co-variance and repeated measures analysis of co-variance methods. The response rate was 47%. Three clusters were obtained: Higher Burnout Lower Quality of Life (n = 62, 20%), Moderate Burnout Moderate Quality of Life (n = 131, 41%), and Lower Burnout Higher Quality of Life (n = 124, 39%). After controlling for gender and year level, Higher Burnout Lower Quality of Life students had significantly higher test anxiety (p Burnout and Quality of Life profiles of medical students are associated with differences in academic motivation and achievement over time.

  8. On the Quality of Global Emission Inventories : Approaches, Methodologies, Input Data and Uncertainties

    NARCIS (Netherlands)

    Olivier, Johannes Gerardus Jozef

    2002-01-01

    This thesis deals with methodological and practical aspects of compiling global emission inventories in relation to their use. The first part of the thesis describes quality aspects from the perspective of the user: i.e. definition, determining factors, practical applications and quantitative

  9. The Assessment of Mangrove Sediment Quality in Mengkabong Lagoon: An Index Analysis Approach

    Science.gov (United States)

    Praveena, Sarva M.; Radojevic, Miroslav; Abdullah, Mohd H.

    2007-01-01

    The objectives of this study are to use different types of indexes to assess the current pollution status in Mengkabong lagoon and select the best index to describe the Mengkabong sediment quality. The indexes used in this study were Enrichment Factor (EF), Geo-accumulation Index (Igeo), Pollution Load Index (PLI) and Marine Sediment Pollution…

  10. [Application of risk-based approach for determination of critical factors in technology transfer of production of medicinal products].

    Science.gov (United States)

    Beregovykh, V V; Spitskiy, O R

    2014-01-01

    Risk-based approach is used for examination of impact of different factors on quality of medicinal products in technology transfer. A general diagram is offered for risk analysis execution in technology transfer from pharmaceutical development to production. When transferring technology to full- scale commercial production it is necessary to investigate and simulate production process application beforehand in new real conditions. The manufacturing process is the core factorfor risk analysis having the most impact on quality attributes of a medicinal product. Further importantfactors are linked to materials and products to be handled and manufacturing environmental conditions such as premises, equipment and personnel. Usage of risk-based approach in designing of multipurpose production facility of medicinal products is shown where quantitative risk analysis tool RAMM (Risk Analysis and Mitigation Matrix) was applied.

  11. Improving the quality of health care in the United States of America: the need for a multi-level approach.

    Science.gov (United States)

    Mechanic, David

    2002-07-01

    Serious efforts to address quality require coordinated, multi-faceted, multi-level strategies that address the organisational environments and cultures that affect how care is provided. Most efforts over the past 50 years to improve the care provided by physicians and other clinicians have been individually rather than system based. Such individual interventions to modify physician behaviour typically have only modest effects whether considering the recognition and treatment of depression in primary care, following established practice guidelines, carrying out preventive interventions, monitoring and managing chronic illness appropriately, or managing pain and end-of-life care. It is increasingly recognised that quality of care is a property of health systems. Internal efforts to shape clinical routines, such as performance incentives and disease-management approaches, and external inducements and constraints that shape how clinical contexts are organised and function are equally relevant. Internal factors include the skills training of clinical personnel, organisational procedures and mechanisms to coordinate care and prevent errors, implementation of best practices, effective use of informational technologies and appropriate incentives. External factors include broader financial and reimbursement mechanisms, regulatory arrangements that protect access and patient rights in situations of vulnerability and performance-based contracts. The mobilisation of effective advocacy, independent and non-profit statutory watchdog organisations, and good consumer information can facilitate and reinforce quality efforts. System integration is admittedly difficult, and always incomplete, but movement toward this goal is an essential strategic objective.

  12. Quality indicators for colorectal cancer surgery and care according to patient-, tumor-, and hospital-related factors

    Directory of Open Access Journals (Sweden)

    Mathoulin-Pélissier Simone

    2012-07-01

    Full Text Available Abstract Background Colorectal cancer (CRC care has improved considerably, particularly since the implementation of a quality of care program centered on national evidence-based guidelines. Formal quality assessment is however still needed. The aim of this research was to identify factors associated with practice variation in CRC patient care. Methods CRC patients identified from all cancer centers in South-West France were included. We investigated variations in practices (from diagnosis to surgery, and compliance with recommended guidelines for colon and rectal cancer. We identified factors associated with three colon cancer practice variations potentially linked to better survival: examination of ≥12 lymph nodes (LN, non-use and use of adjuvant chemotherapy for stage II and stage III patients, respectively. Results We included 1,206 patients, 825 (68% with colon and 381 (32% with rectal cancer, from 53 hospitals. Compliance was high for resection, pathology report, LN examination, and chemotherapy use for stage III patients. In colon cancer, 26% of stage II patients received adjuvant chemotherapy and 71% of stage III patients. 84% of stage US T3T4 rectal cancer patients received pre-operative radiotherapy. In colon cancer, factors associated with examination of ≥12 LNs were: lower ECOG score, advanced stage and larger hospital volume; factors negatively associated were: left sided tumor location and one hospital district. Use of chemotherapy in stage II patients was associated with younger age, advanced stage, emergency setting and care structure (private and location; whereas under-use in stage III patients was associated with advanced age, presence of comorbidities and private hospitals. Conclusions Although some changes in practices may have occurred since this observational study, these findings represent the most recent report on practices in CRC in this region, and offer a useful methodological approach for assessing quality of care

  13. An immunologic approach to induction of epidermal growth factor deficiency

    DEFF Research Database (Denmark)

    Raaberg, Lasse; Nexø, Ebba; Poulsen, Steen Seier;

    1995-01-01

    Epidermal growth factor (EGF) in pharmacologic doses is able to induce growth and development in the fetus and the newborn. To investigate the opposite situation, the effects of insufficient amounts of EGF during development, we wanted to establish an in vivo model with a state of EGF deficiency......(-9) mol/L. The antibodies recognized purified EGF from the submandibular glands (6 kD) and from urine (45 kD) and further native EGF in saliva and urine. The cross-reactivity toward transforming growth factor-alpha was below 3%. Binding of EGF by antibodies inhibited its binding to the EGF...

  14. Replicating hedge fund returns: A factor model approach

    OpenAIRE

    Naser, Omar

    2007-01-01

    Growth in the Hedge Fund industry mirrors the growth in the Mutual Fund industry. This raises the possibility of creating a passive strategy that replicates Hedge Fund returns at lower cost using liquid, exchange-traded instruments. Using monthly returns for the period 1991-2005 on thirteen Hedge Fund strategies, I build a linear factor models (“clones”) that replicate Hedge Fund returns. I use six common factors to determine the amount of expected return and variation in returns that can be ...

  15. Headspace screening: A novel approach for fast quality assessment of the essential oil from culinary sage.

    Science.gov (United States)

    Cvetkovikj, Ivana; Stefkov, Gjoshe; Acevska, Jelena; Karapandzova, Marija; Dimitrovska, Aneta; Kulevanova, Svetlana

    2016-07-01

    Quality assessment of essential oil (EO) from culinary sage (Salvia officinalis L., Lamiaceae) is limited by the long pharmacopoeial procedure. The aim of this study was to employ headspace (HS) sampling in the quality assessment of sage EO. Different populations (30) of culinary sage were assessed using GC/FID/MS analysis of the hydrodistilled EO (pharmacopoeial method) and HS sampling directly from leaves. Compound profiles from both procedures were evaluated according to ISO 9909 and GDC standards for sage EO quality, revealing compliance for only 10 populations. Factors to convert HS values, for the target ISO and GDC components, into theoretical EO values were calculated. Statistical analysis revealed a significant relationship between HS and EO values for seven target components. Consequently, HS sampling could be used as a complementary extraction technique for rapid screening in quality assessment of sage EOs.

  16. Inverse Problem of Air Filtration of Nanoparticles: Optimal Quality Factors of Fibrous Filters

    Directory of Open Access Journals (Sweden)

    Dahua Shou

    2015-01-01

    Full Text Available Application of nanofibers has become an emerging approach to enhance filtration efficiency, but questions arise about the decrease in Quality factor (QF for certain particles due to the rapidly increasing pressure drop. In this paper, we theoretically investigate the QF of dual-layer filters for filtration of monodisperse and polydisperse nanoparticles. The inverse problem of air filtration, as defined in this work, consists in determining the optimal construction of the two-layer fibrous filter with the maximum QF. In comparison to a single-layer substrate, improved QF values for dual-layer filters are found when a second layer with proper structural parameters is added. The influences of solidity, fiber diameter, filter thickness, face velocity, and particle size on the optimization of QF are studied. The maximum QF values for realistic polydisperse particles with a lognormal size distribution are also found. Furthermore, we propose a modified QF (MQF accounting for the effects of energy cost and flow velocity, which are significant in certain operations. The optimal MQF of the dual-layer filter is found to be over twice that of the first layer. This work provides a quick tool for designing and optimizing fibrous structures with better performance for the air filtration of specific nanoparticles.

  17. The Association Between Sleep Quality and Metabolic Factors and Anthropometric Measurements

    Directory of Open Access Journals (Sweden)

    Khorasani

    2016-08-01

    Full Text Available Background Several studies have shown that sleep disorders may lead to metabolic or endocrine changes including insulin resistance, diabetes, obesity, cardiovascular disease and stroke. Objectives The aim of this study was to investigate the association between sleep quality and metabolic factors and anthropometric measurements among personnel of a central petrochemical company in Tehran. Methods This cross-sectional study was conducted on 400 personnel of a central petrochemical company in Tehran, during year 2015. Demographic information including age, gender, educational status, employment duration, working hours per day, marital status, smoking, medical history for disease and drug use, were collected by a questionnaire. Systolic and diastolic blood pressure and also height and weight were measured by standard methods and body mass index (BMI was calculated. Pittsburg sleep quality index (PSQI was performed to assess participants’ sleep quality. Serum concentrations of fasting glucose and lipid profiles were measured by the related biochemical kits. Logistic regression analysis was used for multivariate adjusting of factors associated with sleep quality. Results The mean score for participants’ Pittsburgh sleep quality index (PSQI was 4.77 ± 2.62. About 30% of participants had had bad sleep quality. A high body mass index (BMI (P < 0.001 and high waist circumference (P = 0.016 were inversely associated with sleep quality. Serum concentration of very-low-density lipoprotein (VLDL (P = 0.004 and triglyceride (P = 0.001 were statistically higher in participants with lower sleep quality than with those with higher sleep quality. The group with a good sleep quality had a higher serum high density lipoprotein-cholesterol (HDL-c than those with a poor sleep quality (P = 0.034. Being female increased the risk of poor sleep quality by 2.5 folds, and with increasing BMI (OR = 1.17 and serum triglyceride (OR = 1.02 the risk of poor sleep quality

  18. Water Quality Criteria for Copper Based on the BLM Approach in the Freshwater in China

    Science.gov (United States)

    Zhang, Yahui; Zang, Wenchao; Qin, Lumei; Zheng, Lei; Cao, Ying; Yan, Zhenguang; Yi, Xianliang; Zeng, Honghu; Liu, Zhengtao

    2017-01-01

    The bioavailability and toxicity of metals to aquatic organisms are highly dependent on water quality parameters in freshwaters. The biotic ligand model (BLM) for copper is an approach to generate the water quality criteria (WQC) with water chemistry in the ambient environment. However, few studies were carried out on the WQCs for copper based on the BLM approach in China. In the present study, the toxicity for copper to native Chinese aquatic organisms was conducted and the published toxicity data with water quality parameters to Chinese aquatic species were collected to derive the WQCs for copper by the BLM approach. The BLM-based WQCs (the criterion maximum criteria (CMC) and the criterion continuous concentration (CCC)) for copper in the freshwater for the nation and in the Taihu Lake were obtained. The CMC and CCC values for copper in China were derived to be 1.391 μg/L and 0.495 μg/L, respectively, and the CMC and CCC in the Taihu Lake were 32.194 μg/L and 9.697 μg/L. The high concentration of dissolved organic carbon might be a main reason which resulted in the higher WQC values in the Taihu Lake. The WQC of copper in the freshwater would provide a scientific foundation for water quality standards and the environment risk assessment in China. PMID:28166229

  19. Automated quality control methods for sensor data: a novel observatory approach

    Directory of Open Access Journals (Sweden)

    J. R. Taylor

    2012-12-01

    Full Text Available National and international networks and observatories of terrestrial-based sensors are emerging rapidly. As such, there is demand for a standardized approach to data quality control, as well as interoperability of data among sensor networks. The National Ecological Observatory Network (NEON has begun constructing their first terrestrial observing sites with 60 locations expected to be distributed across the US by 2017. This will result in over 14 000 automated sensors recording more than > 100 Tb of data per year. These data are then used to create other datasets and subsequent "higher-level" data products. In anticipation of this challenge, an overall data quality assurance plan has been developed and the first suite of data quality control measures defined. This data-driven approach focuses on automated methods for defining a suite of plausibility test parameter thresholds. Specifically, these plausibility tests scrutinize data range, persistence, and stochasticity on each measurement type by employing a suite of binary checks. The statistical basis for each of these tests is developed and the methods for calculating test parameter thresholds are explored here. While these tests have been used elsewhere, we apply them in a novel approach by calculating their relevant test parameter thresholds. Finally, implementing automated quality control is demonstrated with preliminary data from a NEON prototype site.

  20. Automated quality control methods for sensor data: a novel observatory approach

    Directory of Open Access Journals (Sweden)

    J. R. Taylor

    2013-07-01

    Full Text Available National and international networks and observatories of terrestrial-based sensors are emerging rapidly. As such, there is demand for a standardized approach to data quality control, as well as interoperability of data among sensor networks. The National Ecological Observatory Network (NEON has begun constructing their first terrestrial observing sites, with 60 locations expected to be distributed across the US by 2017. This will result in over 14 000 automated sensors recording more than > 100 Tb of data per year. These data are then used to create other datasets and subsequent "higher-level" data products. In anticipation of this challenge, an overall data quality assurance plan has been developed and the first suite of data quality control measures defined. This data-driven approach focuses on automated methods for defining a suite of plausibility test parameter thresholds. Specifically, these plausibility tests scrutinize the data range and variance of each measurement type by employing a suite of binary checks. The statistical basis for each of these tests is developed, and the methods for calculating test parameter thresholds are explored here. While these tests have been used elsewhere, we apply them in a novel approach by calculating their relevant test parameter thresholds. Finally, implementing automated quality control is demonstrated with preliminary data from a NEON prototype site.