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Sample records for quadriceps muscle

  1. Abdominal muscle and quadriceps strength in chronic obstructive pulmonary disease

    OpenAIRE

    2005-01-01

    Background: Quadriceps muscle weakness is common in chronic obstructive pulmonary disease (COPD) but is not observed in a small hand muscle (adductor pollicis). Although this could be explained by reduced activity in the quadriceps, the observation could also be explained by anatomical location of the muscle or fibre type composition. However, the abdominal muscles are of a similar anatomical and fibre type distribution to the quadriceps, although they remain active in COPD. Cough gastric pre...

  2. [Reconstruction of quadriceps femoris muscle function with muscle transfer].

    Science.gov (United States)

    Fansa, H; Meric, C

    2010-08-01

    Femoral nerve palsy, mostly of iatrogen cause, leads to paresis of quadriceps muscle with complete loss of knee extension. Therapeutical options include neurolysis, nerve reconstruction or functional muscle transplantations. Another concept is the transfer of hamstring muscles as described in post polio surgery. We describe our experience of biceps femoris and semitendinosus muscle transfer for reconstruction of knee extension. From 2003 to 2007 seven patients (mean age 43) with complete loss of knee extension after femoral nerve lesion were treated. Nerve palsy was caused by direct lesion, traction, hematoma after collapse, lesion of lumbosacral plexus and an unclear muscle dystrophy. Indication for muscle transfer was due to long standing muscle paresis. All patients received a transfer of biceps femoris and semitendinosus muscle/tendon into the quadriceps tendon. Patients were immobilised in a cast for 6 weeks in extended knee position. Weight bearing started after 8 weeks. Operations went uneventfully. All patients were able to extend the knee postoperatively against gravity and were able to climb stairs without help. 4 Patients had complete knee extension, 2 had a lack of 20 degrees , one of 30 degrees. Daily routine was possible in all cases. No instability of knee joints occurred postoperatively. In a nerve lesion close to the muscle a nerve reconstruction should be aimed. If not performed or with unsuccessful outcome, muscle transfer is a good option to restore function. All recent studies describe good to excellent results with stable knees, allowing the patient to manage daily routine without assistance and to climb stairs up and down. Long term complications such as dislocation of patella or genu recurvatum were not observed in our patients. The latter results as typical complication in polio from weakening knee flexion through biceps femoris transfer, if the gastrocnemius muscle is not forceful enough. However in an isolated femoral nerve lesion this

  3. Experimental quadriceps muscle pain impairs knee joint control during walking

    DEFF Research Database (Denmark)

    Henriksen, Marius; Alkjaer, Tine; Lund, Hans

    2007-01-01

    of the quadriceps muscle, resulting in impaired knee joint control and joint instability during walking. The changes are similar to those observed in patients with knee pain. The loss of joint control during and after pain may leave the knee joint prone to injury and potentially participate in the chronicity...

  4. Functional changes of human quadriceps muscle injured by eccentric exercise

    Directory of Open Access Journals (Sweden)

    F.V. Serrão

    2003-06-01

    Full Text Available The present study evaluated functional changes of quadriceps muscle after injury induced by eccentric exercise. Maximal isometric torque of quadriceps and the surface electromyography (root mean square, RMS, and median frequency, MDF of the vastus medialis oblique (VMO and vastus lateralis (VL muscles were examined before, immediately after and during the first 7 days after injury. Serum creatine kinase (CK levels and magnetic resonance imaging (MRI were used to identify muscle injury. The subject was used as her own control and percent refers to pre-injury data. Experiments were carried out with a sedentary 23-year-old female. Injury was induced by 4 bouts of 15 maximal isokinetic eccentric contractions (angular velocity of 5º/s; range of motion from 40º to 110º of knee flexion. The isometric torque of the quadriceps (knee at 90º flexion decreased 52% immediately after eccentric exercise and recovered on the 5th day. The highest reduction of RMS occurred on the 2nd day after injury in both VL (63% and VMO (66% and only VL recovered to the pre-injury level on the 7th day. Immediately after injury, the MDF decreased by 5 and 3% (VMO and VL, respectively and recovered one day later. Serum CK levels increased by 109% on the 2nd day and were still increased by 32% on the 7th day. MRI showed large areas of injury especially in the deep region of quadriceps. In conclusion, eccentric exercise decreased the isometric torque and electromyographic signals of quadriceps muscle, which were recovered in one week, despite the muscle regeneration signals.

  5. Partial rupture of the quadriceps muscle in a child

    Directory of Open Access Journals (Sweden)

    Aydemir Gokhan

    2010-09-01

    Full Text Available Abstract Background The quadriceps femoris muscle ruptures usually occur in the middle-aged population. We present a 4-year-old patient with partial rupture of the quadriceps femoris muscle. To our knowledge, this is the youngest patient reported with a quadriceps femoris muscle rupture. Case Presentation A 4-year-old girl admitted to our clinic with left knee pain and limitation in knee movements. Her father reported that she felt pain while jumping on sofa. There was no direct trauma to thigh or knee. We located a palpable soft tissue swelling at distal anterolateral side of thigh. The history revealed that 10 days ago the patient was treated for upper tract respiratory infection with intramuscular Clindamycin for 7 days. When we consulted the patient with her previous doctor and nurse, we learnt that multiple daily injections might be injected to same side of left thigh. MRI showed a partial tear of vastus lateralis muscle matching with the injection sites. The patient treated with long leg half-casting for three weeks. Clinical examination and knee flexion had good results with conservative treatment. Conclusions Multiple intramuscular injections may contribute to damage muscles and make prone to tears with muscle contractions. Doctors and nurses must be cautious to inject from different parts of both thighs.

  6. Reliability of the Q Force; a mobile instrument for measuring isometric quadriceps muscle strength

    NARCIS (Netherlands)

    Douma, K W; Regterschot, G R H; Krijnen, W P; Slager, G E C; van der Schans, C P; Zijlstra, W

    2016-01-01

    BACKGROUND: The ability to generate muscle strength is a pre-requisite for all human movement. Decreased quadriceps muscle strength is frequently observed in older adults and is associated with a decreased performance and activity limitations. To quantify the quadriceps muscle strength and to monito

  7. Reliability of the Q Force; a mobile instrument for measuring isometric quadriceps muscle strength

    NARCIS (Netherlands)

    Douma, K.W.; Regterschot, G.R.H.; Krijnen, W.P.; Slager, G.E.C.; Schans, C.P. van der; Zijlstra, W.

    2016-01-01

    Background: The ability to generate muscle strength is a pre-requisite for all human movement. Decreased quadriceps muscle strength is frequently observed in older adults and is associated with a decreased performance and activity limitations. To quantify the quadriceps muscle strength and to monito

  8. RAPID KNEE-EXTENSIONS TO INCREASE QUADRICEPS MUSCLE ACTIVITY IN PATIENTS WITH TOTAL KNEE ARTHROPLASTY

    DEFF Research Database (Denmark)

    Husted, Rasmus Skov; Wilquin, Lousia; Jakobsen, Thomas Linding

    2017-01-01

    BACKGROUND: Inhibition of the quadriceps muscle and reduced knee-extension strength is common shortly following total knee arthroplasty (weeks to months), due to reduced voluntary activation of the quadriceps muscle. In healthy subjects, strength training with heavy loads is known to increase ago...

  9. Effects of kinesiology taping on repositioning error of the knee joint after quadriceps muscle fatigue.

    Science.gov (United States)

    Han, Jin Tae; Lee, Jung-Hoon

    2014-06-01

    [Purpose] The purpose of this study was to identify the effects of kinesiology taping on repositioning error of the knee joint after quadriceps muscle fatigue. [Subjects] Thirty healthy adults with no orthopaedic or neurological problems participated in this study. [Methods] The repositioning error of the knee joint was measured using a digital goniometer when the subjects extended their dominant-side knee to a random target angle (30°, 45°, or 60°) with their eyes closed, before and after a quadriceps muscle fatigue protocol, and after application of kinesiology tape. [Results] We found that repositioning errors of the dominant-side knee joint increased after quadriceps fatigue compared with no-fatigue conditions. However, kinesiology taping of the quadriceps muscle and patella after quadriceps fatigue significantly decreased repositioning errors of the knee joint. [Conclusion] These results suggest that quadriceps fatigue increases the repositioning error of the knee joint, whereas application of kinesiology tape decreases fatigue-induced joint repositioning error.

  10. Quadriceps muscle contraction protects the anterior cruciate ligament during anterior tibial translation.

    Science.gov (United States)

    Aune, A K; Cawley, P W; Ekeland, A

    1997-01-01

    The proposed skiing injury mechanism that suggests a quadriceps muscle contraction can contribute to anterior cruciate ligament rupture was biomechanically investigated. The effect of quadriceps muscle force on a knee specimen loaded to anterior cruciate ligament failure during anterior tibial translation was studied in a human cadaveric model. In both knees from six donors, average age 41 years (range, 31 to 65), the joint capsule and ligaments, except the anterior cruciate ligament, were cut. The quadriceps tendon, patella, patellar tendon, and menisci were left intact. One knee from each pair was randomly selected to undergo destructive testing of the anterior cruciate ligament by anterior tibial translation at a displacement rate of 30 mm/sec with a simultaneously applied 889 N quadriceps muscle force. The knee flexion during testing was 30 degrees. As a control, the contralateral knee was loaded correspondingly, but only 5 N of quadriceps muscle force was applied. The ultimate load for the knee to anterior cruciate ligament failure when tested with 889 N quadriceps muscle force was 22% +/- 18% higher than that of knees tested with 5 N of force. The linear stiffness increased by 43% +/- 30%. These results did not support the speculation that a quadriceps muscle contraction contributes to anterior cruciate ligament failure. In this model, the quadriceps muscle force protected the anterior cruciate ligament from injury during anterior tibial translation.

  11. A Novel Noninvasive Method for Measuring Fatigability of the Quadriceps Muscle in Noncooperating Healthy Subjects

    National Research Council Canada - National Science Library

    Poulsen, Jesper B; Rose, Martin H; Møller, Kirsten; Perner, Anders; Jensen, Bente R

    2015-01-01

    .... On two occasions, separated by seven days, nonvoluntary isometric contractions (twitch and tetanic) of the quadriceps femoris muscle evoked by transcutaneous electrical muscle stimulation were recorded in twelve healthy adults...

  12. Interplay between body stabilisation and quadriceps muscle activation capacity.

    Science.gov (United States)

    Bampouras, Theodoros M; Reeves, Neil D; Baltzopoulos, Vasilios; Maganaris, Constantinos N

    2017-03-22

    The study aimed to distinguish the effect of stabilisation and muscle activation on quadriceps maximal isometric voluntary contraction (MVC) torque generation. Nine subjects performed (a) an MVC with restrained leg and pelvis (Typical MVC), (b) a Typical MVC with handgrip (Handgrip MVC), (c) an MVC focusing on contracting the knee extensors only (Isolated knee extension MVC), and (d) an MVC with unrestrained leg and pelvis (Unrestrained MVC). Torque and activation capacity between conditions were compared with repeated measures ANOVA and dependent t-tests. EMG (from eleven remote muscles) was compared using Friedman's and Wilcoxon. Typical MVC (277.2±49.6Nm) and Handgrip MVC (261.0±55.4Nm) were higher than Isolated knee extension MVC (210.2±48.3Nm, pMVC (195.2±49.7Nm, pMVC (83.1±15.9%) activation was higher than Isolated knee extension MVC (68.9±24.3%, pMVC and Handgrip MVC (81.8±17.4%) were higher than Unrestrained MVC (64.9±16.2%, pMVC consistently lower than Typical MVC or Handgrip MVC. Stabilisation of the involved segments is the prime concern allowing fuller activation of the muscle, reinforcing the need for close attention to stabilisation during dynamometry-based knee joint functional assessment.

  13. Serial Changes of Quadriceps and Hamstring Muscle Strength Following Total Knee Arthroplasty: A Meta-Analysis.

    Science.gov (United States)

    Moon, Young-Wan; Kim, Hyun-Jung; Ahn, Hyeong-Sik; Lee, Dae-Hee

    2016-01-01

    This meta-analysis was performed to analyze serial changes in thigh muscles, including quadriceps and hamstring muscles, from before to one year after total knee arthroplasty (TKA). All studies sequentially comparing isokinetic quadriceps and hamstring muscle strengths between the TKA side and the contralateral uninjured limb were included in this meta-analysis. Five studies with 7 cohorts were included in this meta-analysis. The mean differences in the strengths of quadriceps and hamstring muscles between the TKA and uninjured sides were greatest three months after surgery (26.8 N∙m, 12.8 N∙m, Pstrengths relative to preoperative levels were 9.2 N∙m and 4.9 N∙m, respectively, three months postoperatively (P = 0.041), but were no longer significant after six months and one year. During the year after TKA, quadriceps and hamstring muscle strengths were lowest after 3 months, recovering to preoperative level after six months, but not reaching the muscle strength on the contralateral side. Relative to preoperative levels, the difference in muscle strength between the TKA and contralateral knees was only significant at three months. Because decrease of strength of the quadriceps was significantly greater than decrease in hamstring muscle strength at postoperative three months, early rehabilitation after TKA should focus on recovery of quadriceps muscle strength.

  14. The effect of knee injury on the number of muscle fibres in the human quadriceps femoris.

    Science.gov (United States)

    Young, A; Hughes, I; Round, J M; Edwards, R H

    1982-02-01

    By means of ultrasound scanning, bilateral measurements of the cross-sectional area of the quadriceps muscle groups were made in 14 young adults with unilateral thigh muscle wasting after knee injury. Needle biopsy specimens from the lateral mass of the muscle were used to estimate the myofibre cross-sectional area for both quadriceps of each subject. 2. The cross-sectional area of the quadriceps of each patient's injured limb was always smaller than that of the contralateral muscle. The wasting was largely localized to the quadriceps, with relative sparing of the other thigh muscles. 3. None of the biopsies showed any abnormality apart from the reduction in fibre size. In each case, the injured limb's reduced quadriceps cross-sectional area was associated with a reduced mean fibre area. 4. The ratio of the cross-sectional area of a muscle to its mean fibre area is a reduced mean fibre area. 4. The ratio of the cross-sectional area of a muscle to its mean fibre area is a function of the number of fibres it contains. The ratio varied considerably from patient to patient but there was close agreement between the values obtained for the two limbs of each patient. 5. The quadriceps wasting produced by knee injury was due to muscle fibre atrophy. There was no evidence for a change in the number of fibres in the muscle.

  15. Effects of Kinesio Tape application to quadriceps muscles on isokinetic muscle strength, gait, and functional parameters in patients with stroke.

    Science.gov (United States)

    Ekiz, Timur; Aslan, Meryem Doğan; Özgirgin, Neşe

    2015-01-01

    The aim of this study was to evaluate the effects of Kinesio Tape (KT) application to quadriceps muscles on isokinetic muscle strength, gait, and functional parameters in patients with stroke. Twenty-four patients were allocated into KT and control groups. All patients participated in the same conventional rehabilitation program 5 times/wk for 4 wk. In addition, KT was applied to quadriceps muscles bilaterally to the patients in the KT group. Compared with baseline, peak torque levels increased significantly in both groups (all p 0.05). KT application to quadriceps muscles in addition to conventional exercises for 4 wk is effective on isokinetic but not functional parameters.

  16. Acute effects of static stretching on muscle-tendon mechanics of quadriceps and plantar flexor muscles.

    Science.gov (United States)

    Bouvier, Tom; Opplert, Jules; Cometti, Carole; Babault, Nicolas

    2017-07-01

    This study aimed to determine the acute effects of static stretching on stiffness indexes of two muscle groups with a contrasting difference in muscle-tendon proportion. Eleven active males were tested on an isokinetic dynamometer during four sessions randomly presented. Two sessions were dedicated to quadriceps and the two others to triceps surae muscles. Before and immediately after the stretching procedure (5 × 30 s), gastrocnemius medialis and rectus femoris fascicle length and myotendinous junction elongation were determined using ultrasonography. Passive and maximal voluntary torques were measured. Fascicle and myotendinous junction stiffness indexes were calculated. After stretching, maximal voluntary torque similarly decreased for both muscle groups. Passive torque significantly decreased on triceps surae and remained unchanged on quadriceps muscles. Fascicle length increased similarly for both muscles. However, myotendinous junction elongation remained unchanged for gastrocnemius medialis and increased significantly for rectus femoris muscle. Fascicle stiffness index significantly decreased on medial gastrocnemius and remained unchanged on rectus femoris muscle. In contrast, myotendinous junction stiffness index similarly decreased on both muscles. Depending on the muscle considered, the present results revealed different acute stretching effects. This muscle dependency appeared to affect primarily fascicle stiffness index rather than the myotendinous junction.

  17. DEVELOPMENTS IN THE USE OF THE HAMSTRING/QUADRICEPS RATIO FOR THE ASSESSMENT OF MUSCLE BALANCE

    Directory of Open Access Journals (Sweden)

    Gerard Garbutt

    2002-09-01

    Full Text Available Isokinetic moment ratios of the hamstrings (H and quadriceps (Q muscle groups, and their implication in muscle imbalance, have been investigated for more than three decades. The conventional concentric H/Q ratio with its normative value of 0.6 has been at the forefront of the discussion. This does not account for the joint angle at which moment occurs and the type of muscle action involved. Advances towards more functional analyses have occurred such that previous protocols are being re-examined raising questions about their ability to demonstrate a relationship between thigh muscle imbalance and increased incidence or risk of knee injury. This article addresses the function of the hamstring-quadriceps ratio in the interpretation of this relationship using the ratios Hecc/Qcon (ratio of eccentric hamstring strength to concentric quadriceps strength, representative of isolated knee extension and Hcon/Qecc (ratio of concentric hamstring strength to eccentric quadriceps strength, representative of isolated knee flexion.

  18. Morphometric analyses of normal pediatric brachial biceps and quadriceps muscle tissue

    National Research Council Canada - National Science Library

    Sallum, Adriana M E; Varsani, Hemlata; Holton, Janice L; Marie, Suely K N; Wedderburn, Lucy R

    2013-01-01

    Pediatric normal brachial biceps (14 specimens) and quadriceps muscles (14 specimens) were studied by immunohistochemistry to quantify fiber-type, diameter and distribution, capillary density, presence of inflammatory cells...

  19. Functional and morphological changes in the quadriceps muscle induced by eccentric training after ACL reconstruction

    OpenAIRE

    Brasileiro,Jamilson S.; Pinto,Olga M. S. F.; Mariana A. Ávila; Tania F. Salvini

    2011-01-01

    OBJECTIVES: The purpose of this study was to investigate the contributions of functional and morphological factors in the recovery of the quadriceps muscle after anterior cruciate ligament (ACL) reconstruction. METHODS: Nine subjects (31.3±5.8 years) underwent eccentric exercise sessions twice a week for 12 weeks. Quadriceps muscle function was evaluated using an isokinetic dynamometer (isometric and eccentric peak torque) and electromyography (RMS). Morphological changes were measured using ...

  20. Neuromuscular adjustments of the quadriceps muscle after repeated cycling sprints.

    Directory of Open Access Journals (Sweden)

    Olivier Girard

    Full Text Available PURPOSE: This study investigated the supraspinal processes of fatigue of the quadriceps muscle in response to repeated cycling sprints. METHODS: Twelve active individuals performed 10 × 6-s "all-out" sprints on a cycle ergometer (recovery = 30 s, followed 6 min later by 5 × 6-s sprints (recovery = 30 s. Transcranial magnetic and electrical femoral nerve stimulations during brief (5-s and sustained (30-s isometric contractions of the knee extensors were performed before and 3 min post-exercise. RESULTS: Maximal strength of the knee extensors decreased during brief and sustained contractions (~11% and 9%, respectively; P0.05. While cortical voluntary activation declined (P 40% reduced (P<0.001 following exercise. CONCLUSION: The capacity of the motor cortex to optimally drive the knee extensors following a repeated-sprint test was shown in sustained, but not brief, maximal isometric contractions. Additionally, peripheral factors were largely involved in the exercise-induced impairment in neuromuscular function, while corticospinal excitability was well-preserved.

  1. Serial Changes of Quadriceps and Hamstring Muscle Strength Following Total Knee Arthroplasty: A Meta-Analysis.

    Directory of Open Access Journals (Sweden)

    Young-Wan Moon

    Full Text Available This meta-analysis was performed to analyze serial changes in thigh muscles, including quadriceps and hamstring muscles, from before to one year after total knee arthroplasty (TKA. All studies sequentially comparing isokinetic quadriceps and hamstring muscle strengths between the TKA side and the contralateral uninjured limb were included in this meta-analysis. Five studies with 7 cohorts were included in this meta-analysis. The mean differences in the strengths of quadriceps and hamstring muscles between the TKA and uninjured sides were greatest three months after surgery (26.8 N∙m, 12.8 N∙m, P<0.001, but were similar to preoperative level at six months (18.4 N∙m, 7.4 N∙m P<0.001 and were maintained for up to one year (15.9 N∙m, 4.1 N∙m P<0.001. The pooled mean differences in changes in quadriceps and hamstring strengths relative to preoperative levels were 9.2 N∙m and 4.9 N∙m, respectively, three months postoperatively (P = 0.041, but were no longer significant after six months and one year. During the year after TKA, quadriceps and hamstring muscle strengths were lowest after 3 months, recovering to preoperative level after six months, but not reaching the muscle strength on the contralateral side. Relative to preoperative levels, the difference in muscle strength between the TKA and contralateral knees was only significant at three months. Because decrease of strength of the quadriceps was significantly greater than decrease in hamstring muscle strength at postoperative three months, early rehabilitation after TKA should focus on recovery of quadriceps muscle strength.

  2. Contractile properties of the quadriceps muscle in individuals with spinal cord injury

    NARCIS (Netherlands)

    Gerrits, H L; De Haan, A; Hopman, M T; van Der Woude, L H; Jones, D A; Sargeant, A J

    1999-01-01

    Selected contractile properties and fatigability of the quadriceps muscle were studied in seven spinal cord-injured (SCI) and 13 able-bodied control (control) individuals. The SCI muscles demonstrated faster rates of contraction and relaxation than did control muscles and extremely large force oscil

  3. Rapid knee-extensions to increase quadriceps muscle activity in patients with total knee arthroplasty

    DEFF Research Database (Denmark)

    Husted, Rasmus Skov; Wilquin, Lousia; Jakobsen, Thomas Linding

    2017-01-01

    BACKGROUND: Inhibition of the quadriceps muscle and reduced knee-extension strength is common shortly following total knee arthroplasty (weeks to months), due to reduced voluntary activation of the quadriceps muscle. In healthy subjects, strength training with heavy loads is known to increase...... agonist muscle activity, especially if the exercise is conducted using rapid muscle contractions. PURPOSE: The purpose of this study was to examine if patients with total knee arthroplasty could perform rapid knee-extensions using a 10 RM load four to eight weeks after surgery, and the degree to which...... rapid knee-extensions were associated with greater voluntary quadriceps muscle activity during an experimental strength training session, compared to that elicited using slow knee-extensions. STUDY DESIGN: A randomized cross-over study. METHODS: Twenty-four patients (age 66.5) 4-8 weeks post total knee...

  4. Localized muscle vibration reverses quadriceps muscle hypotrophy and improves physical function: a clinical and electrophysiological study.

    Science.gov (United States)

    Benedetti, Maria Grazia; Boccia, Gennaro; Cavazzuti, Lorenzo; Magnani, Elena; Mariani, Elisabetta; Rainoldi, Alberto; Casale, Roberto

    2017-07-18

    Quadriceps weakness has been associated with knee osteoarthritis (OA). High-frequency localized muscle vibration (LMV) has been proposed recently for quadriceps strengthening in patients with knee OA. The purpose of this study was (a) to investigate the clinical effectiveness of high-frequency LMV on quadriceps muscle in patients with knee OA and (b) to disentangle, by means of surface electromyography (sEMG), the underlying mechanism. Thirty patients, aged between 40 and 65 years, and clinically diagnosed with knee OA were included in this randomized, controlled, single-blinded pilot study. Participants were randomly assigned to two groups: a study group treated with LMV, specifically set for muscle strengthening (150 Hz), by means of a commercial device VIBRA, and a control group treated with neuromuscular electrical stimulation. Clinical outcome was measured using the Western Ontario and McMaster Universities Osteoarthritis Index, Visual Analogue Scale, knee range of motion, Timed Up and Go test, and Stair climbing test. To assess changes in muscle activation and fatigue a subgroup of 20 patients was studied with the use of sEMG during a sustained isometric contraction. The LMV group showed a significant change in Western Ontario and McMaster Universities Osteoarthritis Index score, Visual Analogue Scale score, Timed Up and Go test, Stair Climbing Test, and knee flexion. These improvements were not significant in patients treated with neuromuscular electrical stimulation. sEMG analysis suggested an increased involvement of type II muscle fibers in the group treated with LMV. In conclusion, the present study supports the effectiveness of local vibration in muscle function and clinical improvement of patients with knee OA.

  5. [Amino acid composition of the rat quadriceps femoris muscle after a flight on the Kosmos-936 biosatellite].

    Science.gov (United States)

    Vlasova, T F; Miroshnikova, E B; Poliakov, V V; Murugova, T P

    1982-01-01

    The amino acid composition of the quadriceps muscle of rats flown onboard the biosatellite Cosmos-936 and exposed to the ground-based synchronous control experiment was studied. The weightless rats showed changes in the amino acid concentration in the quadriceps muscle. The centrifuged flight and synchronous rats displayed an accumulation of free amino acids in the above muscle.

  6. Progressive fibrosis of the quadriceps muscle FIBROSIS PROGRESIVA DEL CUÁDRICEPS

    OpenAIRE

    Enrique Vergara-Amador; Jorge Andrés Largo González

    2011-01-01

    Background. Fibrosis of the quadriceps in children is a frequently reported pathology which is associated with antibiotics having been injected into the thigh. This study presents a series of patients having a common background of having had a single pentavalent vaccine dose or injectable vitamin K and presenting progressive fibrosis of the quadriceps muscle. Materials and methods. Seven children were found who had progressive unilateral retraction of the knee. Six of them had a background of...

  7. The Isolated Effect of Adductor Canal Block on Quadriceps Femoris Muscle Strength After Total Knee Arthroplasty

    DEFF Research Database (Denmark)

    Sørensen, Johan Kløvgaard; Jæger, Pia; Dahl, Jørgen Berg

    2016-01-01

    BACKGROUND: Using peripheral nerve block after total knee arthroplasty (TKA), without impeding mobility, is challenging. We hypothesized that the analgesic effect of adductor canal block (ACB) could increase the maximum voluntary isometric contraction (MVIC) of the quadriceps femoris muscle after......, expressed as a percentage of postoperative preblock values. In this manner, the effect of the ACB could be isolated from the detrimental effect on muscle strength caused by the surgery. Secondary end points were differences between groups in mobility and pain scores. We planned a subgroup analysis dividing......: ACB improves quadriceps femoris muscle strength, but whether this translates into enhanced mobility is not clearly supported by this study....

  8. Quadriceps Contusion

    Science.gov (United States)

    ... are: An intramuscular contusion , which is when a muscle tears within the sheath (lining) that surrounds it. An ... it might be needed if there's a complete muscle tear or if a quadriceps contusion doesn't heal ...

  9. A novel noninvasive method for measuring fatigability of the quadriceps muscle in noncooperating healthy subjects

    DEFF Research Database (Denmark)

    Poulsen, Jesper Brøndum; Rose, Martin Høyer; Møller, Kirsten;

    2015-01-01

    Background. Critical illness is associated with muscle weakness leading to long-term functional limitations. Objectives. To assess the reliability of a novel method for evaluating fatigability of the quadriceps muscle in noncooperating healthy subjects. Methods. On two occasions, separated by sev...

  10. Restorative Effect of Vitamin D Deficiency on Knee Pain and Quadriceps Muscle Strength in Knee Osteoarthritis

    Directory of Open Access Journals (Sweden)

    Behzad Heidari

    2015-10-01

    Full Text Available Both vitamin D deficiency and quadriceps muscle weakness are associated with kneeosteoarthritis (KOA and pain. The aim of this study was to determine the restorative effect of vitamin Ddeficiency on pain and quadriceps muscle strength in knee osteoarthritis. Patients with KOA aged≥30years, the presence of knee pain for at least one month or longer and serum 25-hydroxyvitamin (25-OHDdeficiencies were recruited in the study. Participants with KOA compatible with Kellgren-Lawrence grade4, joint instability, and effusion, history of surgery or inflammatory arthropathies were excluded. Serum25-OHD was assessed by ELISA method and concentrationsQuadriceps muscle strength was measured by dynamometry method and intensity of knee pain by WesternOntario and McMaster University Osteoarthritis index scored by Likert scale and visual analog scale. Allparticipants received 50.000 IU oral cholecalciferol weekly for at least two months. The influence ofraising serum 25-OHD on quadriceps muscle strength and pain was assessed by calculation of meanchanges from baseline at the end of the treatment period using paired t-test. A total of 67 patients withmean age of 50±6.6 years of age were treated for 2 months. Serum 25-OHD reached to sufficient levels inall except one patient. At the end of the study period, serum 25-OHD and quadriceps muscle strengthincreased significantly as compared with baseline (P=0.007 and P=0.002, respectively, whereas knee paindecreased significantly based on Western Ontario and McMaster University Osteoarthritis index (P=0.001as well as visual analogue scale scores (P=0.001.These findings indicated that correction of vitamin Ddeficiency in patients with KOA exerts a significant favorable effect on quadriceps muscle strength andknee pain.

  11. Oxidative stress participates in quadriceps muscle dysfunction during the initiation of osteoarthritis in rats.

    Science.gov (United States)

    Hsu, Dur-Zong; Chu, Pei-Yi; Wu, Po-Ting; Shen, Po-Chuan; Jou, I-Ming

    2015-01-01

    Osteoarthritis is the most common form of arthritis, affecting approximately 15% of the population. Quadriceps muscle weakness is one of the risk factors of osteoarthritis development. Oxidative stress has been reported to play an important role in the pathogenesis of various muscle dysfunction; however, whether it is involved in osteoarthritis-associated quadriceps muscle weakness has never been investigated. The aim of the present study is to examine the involvement of oxidative stress in quadriceps muscle dysfunction in the initiation of osteoarthritis in rats. Rat osteoarthritis was initiated by conducting meniscectomy (MNX). Quadriceps muscle dysfunction was evaluated by assessing muscular interleukin-6, citrate synthase activity, and myosin heavy chain IIa mRNA expression levels. Muscular oxidative stress was assessed by determining lipid peroxidation, Nrf2 expression, reactive oxygen species, and circulating antioxidants. Increased muscular interleukin-6 production as well as decreased citrate synthase activity and myosin heavy chain IIa mRNA expression were observed at 7 and 14 days after MNX. Biomarkers of oxidative stress were significantly increased after MNX. Muscular free radical counts were increased while glutathione and glutathione peroxidase expression were decreased in MNX-treated rats. We conclude that oxidative stress may be involved in the pathogenesis of muscle dysfunction in MNX-induced osteoarthritis.

  12. Influence of Anterior Cruciate Ligament Tear on Thigh Muscle Strength and Hamstring-to-Quadriceps Ratio: A Meta-Analysis.

    Science.gov (United States)

    Kim, Hyun-Jung; Lee, Jin-Hyuck; Ahn, Sung-Eun; Park, Min-Ji; Lee, Dae-Hee

    2016-01-01

    Theoretical compensation after anterior cruciate ligament (ACL) tear could cause quadriceps weakness and hamstring activation, preventing anterior tibial subluxation and affecting the expected hamstring-to-quadriceps ratio. Although quadriceps weakness often occurs after ACL tears, it remains unclear whether hamstring strength and hamstring-to-quadriceps ratio increase in ACL deficient knees. This meta-analysis compared the isokinetic muscle strength of quadriceps and hamstring muscles, and the hamstring-to-quadriceps ratio, of the injured and injured limbs of patients with ACL tears. This meta-analysis included all studies comparing isokinetic thigh muscle strengths and hamstring-to-quadriceps ratio in the injured and uninjured legs of patients with ACL tear, without or before surgery. Thirteen studies were included in the meta-analysis. Quadriceps and hamstring strengths were 22.3 N∙m (95% CI: 15.2 to 29.3 N∙m; Pmuscles of patients with ACL tear, with the decrease in quadriceps strength being 3-fold greater. These uneven reductions slightly increase the hamstring-to-quadriceps ratio in ACL deficient knees.

  13. Influence of Anterior Cruciate Ligament Tear on Thigh Muscle Strength and Hamstring-to-Quadriceps Ratio: A Meta-Analysis.

    Directory of Open Access Journals (Sweden)

    Hyun-Jung Kim

    Full Text Available Theoretical compensation after anterior cruciate ligament (ACL tear could cause quadriceps weakness and hamstring activation, preventing anterior tibial subluxation and affecting the expected hamstring-to-quadriceps ratio. Although quadriceps weakness often occurs after ACL tears, it remains unclear whether hamstring strength and hamstring-to-quadriceps ratio increase in ACL deficient knees. This meta-analysis compared the isokinetic muscle strength of quadriceps and hamstring muscles, and the hamstring-to-quadriceps ratio, of the injured and injured limbs of patients with ACL tears. This meta-analysis included all studies comparing isokinetic thigh muscle strengths and hamstring-to-quadriceps ratio in the injured and uninjured legs of patients with ACL tear, without or before surgery. Thirteen studies were included in the meta-analysis. Quadriceps and hamstring strengths were 22.3 N∙m (95% CI: 15.2 to 29.3 N∙m; P<0.001 and 7.4 N∙m (95% CI: 4.3 to 10.5 N∙m; P<0.001 lower, respectively, on the injured than on the uninjured side. The mean hamstring-to-quadriceps ratio was 4% greater in ACL deficient than in uninjured limbs (95% CI: 1.7% to 6.3%; P<0.001. Conclusively, Decreases were observed in both the quadriceps and hamstring muscles of patients with ACL tear, with the decrease in quadriceps strength being 3-fold greater. These uneven reductions slightly increase the hamstring-to-quadriceps ratio in ACL deficient knees.

  14. The evaluation of muscle recovery after anatomical single-bundle ACL reconstruction using a quadriceps autograft.

    Science.gov (United States)

    Iriuchishima, Takanori; Ryu, Keinosuke; Okano, Tatsumasa; Suruga, Makoto; Aizawa, Shin; Fu, Freddie H

    2017-05-01

    The purpose of this study was to reveal the degree of muscle recovery and report the clinical results of anatomical single-bundle ACL reconstruction using a quadriceps autograft. Twenty subjects undergoing anatomical single-bundle ACL reconstruction using a quadriceps autograft were included in this study. A 5-mm-wide, 8-cm-long graft, involving the entire layer of the quadriceps tendon, was harvested without bone block. The average graft diameter was 8.1 ± 1.4 mm. An initial tension of 30 N was applied. The femoral tunnel was created from the far-medial portal. Each femoral and tibial tunnel was created close to the antero-medial bundle insertion site. For the evaluation of muscle recovery (quadriceps and hamstring), a handheld dynamometer was used. The evaluation of muscle recovery was performed pre-operatively, and at 3, 6, 9, and 12 months after surgery. Muscle recovery data were calculated as a percentage of leg strength in the non-operated leg. Anterior tibial translation (ATT), pivot shift test, and IKDC score were evaluated. The average quadriceps strength pre-operatively, and at 3, 6, 9, and 12 months after ACL reconstruction was 90.5 ± 19, 67.8 ± 21.4, 84 ± 17.5, and 85.1 ± 12.6 %, respectively. The average hamstring strength pre-operatively, and at 3, 6, 9, and 12 months after ACL reconstruction was 99.5 ± 13.7, 78.7 ± 11.4, 90.5 ± 19, and 96.7 ± 13.8 %, respectively. ATT pre-operatively and at 12 months after surgery was 5.4 ± 1.3 and 1.0 ± 0.8 mm, respectively. No subjects exhibited positive pivot shift after surgery. Within 6 months following surgery, quadriceps hypotrophy was observed in all subjects. However, the hypotrophy had recovered at 12 months following surgery. No subjects complained of donor site pain after surgery. Anatomical single-bundle ACL reconstruction using a quadriceps autograft resulted in equivalent level of muscle recovery and knee stability when compared with previously reported ACL

  15. Force enhancement during and following muscle stretch of maximal voluntarily activated human quadriceps femoris.

    Science.gov (United States)

    Hahn, Daniel; Seiberl, Wolfgang; Schwirtz, Ansgar

    2007-08-01

    Force enhancement during and following muscle stretch has been observed for electrically and voluntarily activated human muscle. However, especially for voluntary contractions, the latter observation has only been made for adductor pollicis and the ankle joint muscles, but not for large muscles like quadriceps femoris. Therefore, the aim of this study was to investigate the effects of active muscle stretch on force production for maximal voluntary contractions of in vivo human quadriceps femoris (n = 15). Peak torques during and torques at the end of stretch, torques following stretch, and passive torques following muscle deactivation were compared to the isometric torques at corresponding muscle length. In addition, muscle activation of rectus femoris, vastus medialis and vastus lateralis was obtained using surface EMG. Stretches with different amplitudes (15, 25 and 35 degrees at a velocity of 60 degrees s(-1)) were performed on the plateau region and the descending limb of the force-length relation in a random order. Data analysis showed four main results: (1) peak torques did not occur at the end of the stretch, but torques at the end of the stretch exceeded the corresponding isometric torque; (2) there was no significant force enhancement following muscle stretch, but a small significant passive force enhancement persisted for all stretch conditions; (3) forces during and following stretch were independent of stretch amplitude; (4) muscle activation during and following muscle stretch was significantly reduced. In conclusion, although our results showed passive force enhancement, we could not provide direct evidence that there is active force enhancement in voluntarily activated human quadriceps femoris.

  16. Effect of eccentric exercise-induced muscle damage on electromyographyic activity of quadriceps in untrained healthy females.

    Science.gov (United States)

    Rezaei, Mandana; Ebrahimi-Takamjani, Ismael; Jamshidi, Ali A; Vassaghi-Gharamaleki, Behnoush; Hedayatpour, Nosratollah; Havaei, Naser

    2014-01-01

    The aim of this study was to investigate muscle damage indicators and electromyography activities of quadriceps muscles at 25° of hip flexion in untrained healthy females after an eccentric exercise induced muscle fiber damage. A total of 14 healthy females participated in this pre-experimental study. The subjects performed maximal eccentric quadriceps contractions at 25˚ of hip flexion. Maximum voluntary extensor isometric and concentric moments, angle of maximum moment for concentric contractions, perceived pain intensity, and pain pressure threshold were examined before, immediately, 48 hours, 120 hours and 14 days after eccentric exercise. Additionally, electromyography of three parts of quadriceps muscle, knee flexion range of motion and thigh circumference were measured before and after eccentric exercise. Significant reductions in maximum isometric moment and maximum concentric moment were observed at angular velocity of 60˚ per sec immediately after eccentric exercise (peccentric exercise. Increased pain intensity and decreased knee joint range of motion manifested 48 hours after eccentric exercise. Pain pressure threshold for the quadriceps was higher 14 days after exercise as compared to 48 and 120 hours (p0.05). Eccentric exercise performed at 25˚ of hip flexion resulted in muscle fiber injuries within the quadriceps muscle. However, electromyography of quadriceps muscle was not significantly different than the baseline. The result indicates that hip joint position may modify the effect of eccentric exercise on muscle activation.

  17. Changes in transverse relaxation time of quadriceps femoris muscles after active recovery exercises with different intensities.

    Science.gov (United States)

    Mukaimoto, Takahiro; Semba, Syun; Inoue, Yosuke; Ohno, Makoto

    2014-01-01

    The purpose of this study was to examine the changes in the metabolic state of quadriceps femoris muscles using transverse relaxation time (T2), measured by muscle functional magnetic resonance (MR) imaging, after inactive or active recovery exercises with different intensities following high-intensity knee-extension exercise. Eight healthy men performed recovery sessions with four different conditions for 20 min after high-intensity knee-extension exercise on separate days. During the recovery session, the participants conducted a light cycle exercise for 20 min using a cycle (50%, 70% and 100% of the lactate threshold (LT), respectively: active recovery), and inactive recovery. The MR images of quadriceps femoris muscles were taken before the trial and after the recovery session every 30 min for 120 min. The percentage changes in T2 for the rectus femoris and vastus medialis muscles after the recovery session in 50% LT and 70% LT were significantly lower than those in either inactive recovery or 100% LT. There were no significant differences in those for vastus lateralis and vastus intermedius muscles among the four trials. The percentage changes in T2 of rectus femoris and vastus medialis muscles after the recovery session in 50% LT and 70% LT decreased to the values before the trial faster than those in either inactive recovery or 100% LT. Those of vastus lateralis and vastus intermedius muscles after the recovery session in 50% LT and 70% LT decreased to the values before the trial faster than those in 100% LT. Although the changes in T2 after active recovery exercises were not uniform in exercised muscles, the results of this study suggest that active recovery exercise with the intensities below LT are more effective to recover the metabolic state of quadriceps femoris muscles after intense exercise than with either intensity at LT or inactive recovery.

  18. Adductor canal block can result in motor block of the quadriceps muscle.

    Science.gov (United States)

    Chen, Junping; Lesser, Jonathan B; Hadzic, Admir; Reiss, Wojciech; Resta-Flarer, Francesco

    2014-01-01

    The block of nerves in the adductor canal is considered to cause a sensory block without a motor component. In this report, we describe a case of significant quadriceps muscle weakness after an adductor canal block (ACB). A 65-year-old female patient for ambulatory knee surgery was given an ACB for postoperative pain management. The block was performed under ultrasound guidance at the midthigh level using the transsartorial approach. Twenty milliliters of 0.5% ropivacaine was deposited adjacent to the anterior and posterior areas of the femoral artery. On discharge from the hospital, the patient realized that her thigh muscles were weak and she was unable to extend her leg at the knee. A neuromuscular examination indicated that the patient had no strength in her quadriceps muscle, along with sensory deficit in the medial-anterior lower leg and area in front of knee up to the midthigh. The weakness lasted 20 hours, and the sensory block lasted 48 hours before complete recovery. The optimal level and amount of local anesthetic for adductor canal block are currently not well defined. Proximal spread of local anesthetic and anatomical variation may explain our observation. Several studies have reported that ACB involves no motor blockade. However, our case report illustrates that the ACB can result in clinically significant quadriceps muscle paralysis. This report suggests that patients should be monitored vigilantly for this occurrence to decrease the risk of falls.

  19. Differential glucose uptake in quadriceps and other leg muscles during one-legged dynamic submaximal knee-extension exercise

    OpenAIRE

    Kari eKalliokoski; Robert eBoushel; Henning eLangberg; Celena eScheede-Bergdahl; Ann Kathrine Ryberg; Simon eDoessing; Andreas eKjaer; Michael eKjaer

    2011-01-01

    One-legged dynamic knee-extension exercise (DKE) is a widely used model to study the local cardiovascular and metabolic responses to exercise of the quadriceps muscles. In this study, we explored the extent to which different muscles of the quadriceps are activated during exercise using positron emission tomography (PET) determined uptake of [18F]-fluoro-deoxy-glucose (GU) during DKE. Five healthy male subjects performed DKE at 25 W for 35 min and both the contracting and contralateral resti...

  20. Differential glucose uptake in quadriceps and other leg muscles during one-legged dynamic submaximal knee-extension exercise

    OpenAIRE

    Kari eKalliokoski; Robert eBoushel; Henning eLangberg; Celena eScheede-Bergdahl; Ann Kathrine Ryberg; Simon eDoessing; Andreas eKjaer; Michael eKjaer

    2011-01-01

    One-legged dynamic knee-extension exercise (DKE) is a widely used model to study the local cardiovascular and metabolic responses to exercise of the quadriceps muscles. In this study, we explored the extent to which different muscles of the quadriceps are activated during exercise using positron emission tomography (PET) determined uptake of [18F]-fluoro-deoxy-glucose (GU) during DKE. Five healthy male subjects performed DKE at 25 W for 35 min and both the contracting and contralateral resti...

  1. Static vs. Dynamic Acute Stretching Effect on Quadriceps Muscle Activity during Soccer Instep Kicking

    Science.gov (United States)

    Amiri-Khorasani, Mohammadtaghi; Kellis, Eleftherios

    2013-01-01

    The purpose of this study was to compare the effects of static and dynamic stretching on quadriceps muscle activation during maximal soccer instep kicking. The kicking motion of twelve male college soccer players (body height: 174.66 ± 5.01 cm; body mass: 72.83 ± 4.83 kg; age: 18.83 ± 0.75 years) was captured using six synchronized high-speed infra-red cameras whilst electromyography (EMG) signals from vastus medialis (VM), lateralis (VL) and rectus femoris (RF) were recorded before and after static or dynamic stretching. Analysis of variance designs showed a higher increase in knee extension angular velocity (9.65% vs. −1.45%, p stretching exercises. Based on these results, it could be suggested that dynamic stretching is probably more effective in increasing quadriceps muscle activity and knee extension angular velocity during the final swing phase of a maximal soccer instep kick than static stretching. PMID:24511339

  2. Differential glucose uptake in quadriceps and other leg muscles during one-legged dynamic submaximal knee-extension exercise

    DEFF Research Database (Denmark)

    Kalliokoski, Kari K; Boushel, Robert; Langberg, Henning;

    2011-01-01

    One-legged dynamic knee-extension exercise (DKE) is a widely used model to study the local cardiovascular and metabolic responses to exercise of the quadriceps muscles. In this study, we explored the extent to which different muscles of the quadriceps are activated during exercise using positron...... in the vastus intermedius (VI) and lowest in the vastus lateralis (VL; VI vs VL, p muscles in the exercising leg was 35 ± 9%. Compared...... to mean GU in QF (=100%), GU was on average 73% in VL, 84% in rectus femoris, 115% in vastus medialis, and 142% in VI. Variable activation of hamstring muscles and muscles of the lower leg was also observed. These results show that GU of different muscles of quadriceps muscle group as well as between...

  3. Relationship between quadriceps femoris muscle volume and muscle torque after anterior cruciate ligament repair.

    Science.gov (United States)

    Konishi, Y; Ikeda, K; Nishino, A; Sunaga, M; Aihara, Y; Fukubayashi, T

    2007-12-01

    This study was performed to obtain evidence regarding bilateral hindrance of motor unit (MU) recruitment in the quadriceps femoris (QF) of patients with anterior cruciate ligament (ACL) reconstruction. The subjects included 70 patients who underwent ACL reconstruction and 35 healthy subjects. To identify the muscle torque per unit volume (MTPUV), the peak torque of each velocity of isokinetic performance was divided by muscle volume of the QF measured by a series of cross-sectional images obtained by magnetic resonance imaging scans. Tests revealed that the mean MTPUV of the uninjured (0.113+/-0.03 N m/cm3 at 60 degrees /s, 0.081+/-0.02 N m/cm3 at 180 degrees /s) and injured sides (0.109+/-0.03 N m/cm3 at 60 degrees /s, 0.079+/-0.023 N m/cm3 at 180 degrees /s) were significantly lower than those of the control group (0.144+/-0.05 N m/cm3 at 60 degrees /s, 0.096+/-0.04 N m/cm3 at 180 degrees /s). Previous studies suggested that MU recruitment in the QF of patients with ACL injury was hindered bilaterally. However, the design of their studies could not provide evidence of bilateral hindrance of MU recruitment in the QF. The results of the present study demonstrated that the MTPUV of both injured and uninjured sides of patients were significantly lower than those of the control group.

  4. CHANGES IN QUADRICEPS MUSCLE ACTIVITY DURING SUSTAINED RECREATIONAL ALPINE SKIING

    Directory of Open Access Journals (Sweden)

    Josef Kröll

    2011-03-01

    Full Text Available During a day of skiing thousands of repeated contractions take place. Previous research on prolonged recreational alpine skiing show that physiological changes occur and hence some level of fatigue is inevitable. In the present paper the effect of prolonged skiing on the recruitment and coordination of the muscle activity was investigated. Six subjects performed 24 standardized runs. Muscle activity during the first two (PREskiing and the last two (POSTskiing runs was measured from the vastus lateralis (VL and rectus femoris (RF using EMG and quantified using wavelet and principal component analysis. The frequency content of the EMG signal shifted in seven out of eight cases significantly towards lower frequencies with highest effects observed for RF on outside leg. A significant pronounced outside leg loading occurred during POSTskiing and the timing of muscle activity peaks occurred more towards turn completion. Specific EMG frequency changes were observed at certain time points throughout the time windows and not over the whole double turn. It is suggested that general muscular fatigue, where additional specific muscle fibers have to be recruited due to the reduced power output of other fibers did not occur. The EMG frequency decrease and intensity changes for RF and VL are caused by altered timing (coordination within the turn towards a most likely more uncontrolled skiing technique. Hence, these data provide evidence to suggest recreational skiers alter their skiing technique before a potential change in muscle fiber recruitment occurs

  5. An examination of cross-talk among surface mechanomyographic signals from the superficial quadriceps femoris muscles during isometric muscle actions.

    Science.gov (United States)

    Beck, Travis W; DeFreitas, Jason M; Stock, Matt S

    2010-04-01

    The purpose of this study was to examine cross-talk among the mechanomyographic (MMG) signals from the superficial quadriceps femoris muscles during submaximal to maximal isometric muscle actions of the leg extensors. Eleven healthy men (age=20.1+/-1.1yr, mean+/-SD) volunteered to randomly perform isometric muscle actions in 10% increments from 10% to 90% of the maximum voluntary contraction (MVC). During each muscle action, MMG signals were detected from the vastus lateralis, rectus femoris, and vastus medialis with three separate accelerometers. Cross-correlation was used to quantify cross-talk among the vastus lateralis, rectus femoris, and vastus medialis during each muscle action. The results showed cross-correlation coefficients that ranged from R(x,y)=.124-.714, but generally speaking, the coefficients were between .1 and .3. In addition, there were no consistent differences among the cross-talk levels for the three muscles, and the cross-correlation coefficients generally did not increase with isometric torque. Thus, MMG can be used to examine muscle function from each of the superficial quadriceps femoris muscles during isometric muscle actions.

  6. Effects of Quadriceps Muscle Fatigue on Stiff-Knee Gait in Patients with Hemiparesis

    Science.gov (United States)

    Boudarham, Julien; Roche, Nicolas; Pradon, Didier; Delouf, Eric; Bensmail, Djamel; Zory, Raphael

    2014-01-01

    The relationship between neuromuscular fatigue and locomotion has never been investigated in hemiparetic patients despite the fact that, in the clinical context, patients report to be more spastic or stiffer after walking a long distance or after a rehabilitation session. The aim of this study was to evaluate the effects of quadriceps muscle fatigue on the biomechanical gait parameters of patients with a stiff-knee gait (SKG). Thirteen patients and eleven healthy controls performed one gait analysis before a protocol of isokinetic quadriceps fatigue and two after (immediately after and after 10 minutes of rest). Spatiotemporal parameters, sagittal knee and hip kinematics, rectus femoris (RF) and vastus lateralis (VL) kinematics and electromyographic (EMG) activity were analyzed. The results showed that quadriceps muscle weakness, produced by repetitive concentric contractions of the knee extensors, induced an improvement of spatiotemporal parameters for patients and healthy subjects. For the patient group, the increase in gait velocity and step length was associated with i) an increase of sagittal hip and knee flexion during the swing phase, ii) an increase of the maximal normalized length of the RF and VL and of the maximal VL lengthening velocity during the pre-swing and swing phases, and iii) a decrease in EMG activity of the RF muscle during the initial pre-swing phase and during the latter 2/3 of the initial swing phase. These results suggest that quadriceps fatigue did not alter the gait of patients with hemiparesis walking with a SKG and that neuromuscular fatigue may play the same functional role as an anti-spastic treatment such as botulinum toxin-A injection. Strength training of knee extensors, although commonly performed in rehabilitation, does not seem to be a priority to improve gait of these patients. PMID:24718087

  7. Effects of quadriceps muscle fatigue on stiff-knee gait in patients with hemiparesis.

    Directory of Open Access Journals (Sweden)

    Julien Boudarham

    Full Text Available The relationship between neuromuscular fatigue and locomotion has never been investigated in hemiparetic patients despite the fact that, in the clinical context, patients report to be more spastic or stiffer after walking a long distance or after a rehabilitation session. The aim of this study was to evaluate the effects of quadriceps muscle fatigue on the biomechanical gait parameters of patients with a stiff-knee gait (SKG. Thirteen patients and eleven healthy controls performed one gait analysis before a protocol of isokinetic quadriceps fatigue and two after (immediately after and after 10 minutes of rest. Spatiotemporal parameters, sagittal knee and hip kinematics, rectus femoris (RF and vastus lateralis (VL kinematics and electromyographic (EMG activity were analyzed. The results showed that quadriceps muscle weakness, produced by repetitive concentric contractions of the knee extensors, induced an improvement of spatiotemporal parameters for patients and healthy subjects. For the patient group, the increase in gait velocity and step length was associated with i an increase of sagittal hip and knee flexion during the swing phase, ii an increase of the maximal normalized length of the RF and VL and of the maximal VL lengthening velocity during the pre-swing and swing phases, and iii a decrease in EMG activity of the RF muscle during the initial pre-swing phase and during the latter 2/3 of the initial swing phase. These results suggest that quadriceps fatigue did not alter the gait of patients with hemiparesis walking with a SKG and that neuromuscular fatigue may play the same functional role as an anti-spastic treatment such as botulinum toxin-A injection. Strength training of knee extensors, although commonly performed in rehabilitation, does not seem to be a priority to improve gait of these patients.

  8. Effects of quadriceps muscle fatigue on stiff-knee gait in patients with hemiparesis.

    Science.gov (United States)

    Boudarham, Julien; Roche, Nicolas; Pradon, Didier; Delouf, Eric; Bensmail, Djamel; Zory, Raphael

    2014-01-01

    The relationship between neuromuscular fatigue and locomotion has never been investigated in hemiparetic patients despite the fact that, in the clinical context, patients report to be more spastic or stiffer after walking a long distance or after a rehabilitation session. The aim of this study was to evaluate the effects of quadriceps muscle fatigue on the biomechanical gait parameters of patients with a stiff-knee gait (SKG). Thirteen patients and eleven healthy controls performed one gait analysis before a protocol of isokinetic quadriceps fatigue and two after (immediately after and after 10 minutes of rest). Spatiotemporal parameters, sagittal knee and hip kinematics, rectus femoris (RF) and vastus lateralis (VL) kinematics and electromyographic (EMG) activity were analyzed. The results showed that quadriceps muscle weakness, produced by repetitive concentric contractions of the knee extensors, induced an improvement of spatiotemporal parameters for patients and healthy subjects. For the patient group, the increase in gait velocity and step length was associated with i) an increase of sagittal hip and knee flexion during the swing phase, ii) an increase of the maximal normalized length of the RF and VL and of the maximal VL lengthening velocity during the pre-swing and swing phases, and iii) a decrease in EMG activity of the RF muscle during the initial pre-swing phase and during the latter 2/3 of the initial swing phase. These results suggest that quadriceps fatigue did not alter the gait of patients with hemiparesis walking with a SKG and that neuromuscular fatigue may play the same functional role as an anti-spastic treatment such as botulinum toxin-A injection. Strength training of knee extensors, although commonly performed in rehabilitation, does not seem to be a priority to improve gait of these patients.

  9. Quantifying Quadriceps Muscle Strength in Patients With ACL Injury, Focal Cartilage Lesions, and Degenerative Meniscus Tears

    Science.gov (United States)

    Eitzen, Ingrid; Grindem, Hege; Nilstad, Agnethe; Moksnes, Håvard; Risberg, May Arna

    2016-01-01

    Background: Reduced quadriceps strength influences knee function and increases the risk of knee osteoarthritis. Thus, it is of significant clinical relevance to precisely quantify strength deficits in patients with knee injuries. Purpose: To evaluate isokinetic concentric quadriceps muscle strength torque values, assessed both from peak torque and at specific knee flexion joint angles, in patients with anterior cruciate ligament (ACL) injury, focal cartilage lesions, and degenerative meniscus tears. Study Design: Cohort study; Level of evidence, 3. Methods: Data were synthesized from patients included in 3 previously conducted research projects: 2 prospective cohort studies and 1 randomized controlled trial. At the time of inclusion, all patients were candidates for surgery. Isokinetic concentric quadriceps muscle strength measurements (60 deg/s) were performed at baseline (preoperative status) and after a period of progressive supervised exercise therapy (length of rehabilitation period: 5 weeks for ACL injury, 12 weeks for cartilage lesions and degenerative meniscus). Outcome measures were peak torque and torque at specific knee flexion joint angles from 20° to 70°. All patients had unilateral injuries, and side-to-side deficits were calculated. For comparisons between and within groups, we utilized 1-way analysis of variance and paired t tests, respectively. Results: In total, 250 patients were included. At baseline, cartilage patients had the most severe deficit (39.7% ± 24.3%; P torque was consistently measured at 60° of knee flexion, whereas the largest mean deficits were measured at 30° at baseline and 70° at retest for the ACL group, at 70° at baseline and retest for the degenerative meniscus group, and at 60° at baseline and at 50° at retest for the cartilage group. Conclusion: This study underlines the importance of including torque at specific knee flexion joint angles from isokinetic assessments to identify the most severe quadriceps muscle

  10. Quadriceps muscle fatigue in trained and untrained boys.

    Science.gov (United States)

    Callewaert, M; Boone, J; Celie, B; De Clercq, D; Bourgois, J

    2013-01-01

    This study aimed to explore muscle oxygen extraction and muscle activation pattern during bilateral intermittent submaximal isometric knee-extensions by combining Near-infrared Spectroscopy (NIRS) and Electromyography (EMG) measurements from the M. Vastus Lateralis. A group of highly specifically trained boys (youth sailors) (n=10) and untrained matched controls (n=10) performed 12 bouts of 90 s bilateral submaximal (30-40% MVC) isometric knee-extension interspersed with 6 s recovery-periods. Patterns of deoxygenated haemoglobin and myoglobin concentration (Deoxy[Hb+Mb]) were observed during each bout and the entire protocol. Reoxygenation Index (RI) was assessed for each recovery period as the amplitude of Deoxy[Hb+Mb]-decrease relative to amplitude of Deoxy[Hb+Mb]-increase during each bout. Root Mean Square (RMS) and Mean Power Frequency (MPF) were calculated for each bout as an average of the final 60 s. Deoxy[Hb+Mb], RI, RMS and MPF were analyzed by repeated-measures ANOVA. Results indicated significantly higher Deoxy[Hb+Mb]-increase and lower RI in specifically trained boys compared to untrained controls. These differences are presumably related to the differences in EMG-measurements which demonstrated lower RMS-increase and MPF-decrease for trained compared to untrained boys. In conclusion, specifically trained boys indicate delayed onset of muscle fatigue in comparison to untrained controls, which might be associated with the different pattern of muscle O2-extraction or muscle activation pattern (i. e., a more accurate recruitment of slow-twitch fibres).

  11. Immediate Effects of Kinesiology Taping of Quadriceps on Motor Performance after Muscle Fatigued Induction.

    Science.gov (United States)

    Ahn, Ick Keun; Kim, You Lim; Bae, Young-Hyeon; Lee, Suk Min

    2015-01-01

    Objectives. The purpose of this cross-sectional single-blind study was to investigate the immediate effects of Kinesiology taping of quadriceps on motor performance after muscle fatigued induction. Design. Randomized controlled cross-sectional design. Subjects. Forty-five subjects participated in this study. Participants were divided into three groups: Kinesiology taping group, placebo taping group, and nontaping group. Methods. Subjects performed short-term exercise for muscle fatigued induction, followed by the application of each intervention. Peak torque test, one-leg single hop test, active joint position sense test, and one-leg static balance test were carried out before and after the intervention. Results. Peak torque and single-leg hopping distance were significantly increased when Kinesiology taping was applied (p Kinesiology taping is effective in restoring muscle power reduced after muscle fatigued induction. Therefore, we suggest that Kinesiology taping is beneficial for fatigued muscles.

  12. The associations between quadriceps muscle strength, power, and knee joint mechanics in knee osteoarthritis: A cross-sectional study.

    Science.gov (United States)

    Murray, Amanda M; Thomas, Abbey C; Armstrong, Charles W; Pietrosimone, Brian G; Tevald, Michael A

    2015-12-01

    Abnormal knee joint mechanics have been implicated in the pathogenesis and progression of knee osteoarthritis. Deficits in muscle function (i.e., strength and power) may contribute to abnormal knee joint loading. The associations between quadriceps strength, power and knee joint mechanics remain unclear in knee osteoarthritis. Three-dimensional motion analysis was used to collect peak knee joint angles and moments during the first 50% of stance phase of gait in 33 participants with knee osteoarthritis. Quadriceps strength and power were assessed using a knee extension machine. Strength was quantified as the one repetition maximum. Power was quantified as the peak power produced at 40-90% of the one repetition maximum. Quadriceps strength accounted for 15% of the variance in peak knee flexion angle (P=0.016). Quadriceps power accounted for 20-29% of the variance in peak knee flexion angle (Pknee adduction moment (P=0.05). These data suggest that quadriceps power explains more variance in knee flexion angle and knee adduction moment during gait in knee osteoarthritis than quadriceps strength. Additionally, quadriceps power at multiple loads is associated with knee joint mechanics and therefore should be assessed at a variety of loads. Taken together, these results indicate that quadriceps power may be a potential target for interventions aimed at changing knee joint mechanics in knee osteoarthritis. Copyright © 2015 Elsevier Ltd. All rights reserved.

  13. Differential glucose uptake in quadriceps and other leg muscles during one-legged dynamic submaximal knee-extension exercise

    Directory of Open Access Journals (Sweden)

    Kari eKalliokoski

    2011-10-01

    Full Text Available One-legged dynamic knee-extension exercise (DKE is a widely used model to study the local cardiovascular and metabolic responses to exercise of the quadriceps muscles. In this study, we explored the extent to which different muscles of the quadriceps are activated during exercise using positron emission tomography (PET determined uptake of [18F]-fluoro-deoxy-glucose (GU during DKE. Five healthy male subjects performed DKE at 25 W for 35 min and both the contracting and contralateral resting leg were scanned with PET from mid-thigh and distally. On average, exercise GU was the highest in the vastus intermedius (VI and lowest in the vastus lateralis (VL (VI vs VL, p<0.05, whereas the coefficient of variation was highest in VL (VL vs VI, p<0.05. Coefficient of variation between the mean values of the four QF muscles in the exercising leg was 35±9%. Compared to mean GU in QF (=100%, GU was on average 73% in VL, 84% in rectus femoris, 115% in vastus medialis, and 142% in VI. Variable activation of hamstring muscles and muscles of the lower leg was also observed. These results show that GU of different muscles of quadriceps muscle group as well as between individuals vary greatly during DKE, and suggests that muscle activity is not equal between quadriceps muscles in this exercise model. Furthermore, posterior thigh muscles and lower leg muscles are more active than hitherto thought even during this moderate exercise intensity.

  14. Differential glucose uptake in quadriceps and other leg muscles during one-legged dynamic submaximal knee-extension exercise.

    Science.gov (United States)

    Kalliokoski, Kari K; Boushel, Robert; Langberg, Henning; Scheede-Bergdahl, Celena; Ryberg, Ann Kathrine; Døssing, Simon; Kjær, Andreas; Kjær, Michael

    2011-01-01

    One-legged dynamic knee-extension exercise (DKE) is a widely used model to study the local cardiovascular and metabolic responses to exercise of the quadriceps muscles. In this study, we explored the extent to which different muscles of the quadriceps are activated during exercise using positron emission tomography (PET) determined uptake of [(18)F]-fluoro-deoxy-glucose (GU) during DKE. Five healthy male subjects performed DKE at 25 W for 35 min and both the contracting and contralateral resting leg were scanned with PET from mid-thigh and distally. On average, exercise GU was the highest in the vastus intermedius (VI) and lowest in the vastus lateralis (VL; VI vs VL, p muscles in the exercising leg was 35 ± 9%. Compared to mean GU in QF (=100%), GU was on average 73% in VL, 84% in rectus femoris, 115% in vastus medialis, and 142% in VI. Variable activation of hamstring muscles and muscles of the lower leg was also observed. These results show that GU of different muscles of quadriceps muscle group as well as between individuals vary greatly during DKE, and suggests that muscle activity is not equal between quadriceps muscles in this exercise model. Furthermore, posterior thigh muscles and lower leg muscles are more active than hitherto thought even during this moderate exercise intensity.

  15. Muscle metabolism during graded quadriceps exercise in man

    DEFF Research Database (Denmark)

    Helge, Jørn W; Stallknecht, Bente; Galbo, Henrik

    2007-01-01

    intensity. In conclusion, in the presence of a high blood flow and oxygen supply and only small hormonal changes, total fat oxidation in muscle increases from rest to light exercise, but then remains constant with exercise intensity up to heavy exercise. However, with increasing exercise intensity......, oxidation of plasma free fatty acids increases and accordingly oxidation of other fat sources decreases. These findings are in contrast to whole body measurements performed during graded exercise involving a large muscle mass during which fat oxidation peaks at around 60% of ........27+/-0.03, 0.48+/-0.04, 0.55+/-0.05 l min(-1)) increased (Pincreased (Pfat oxidation (19+/-6, 312+/-64, 356+/-93, 323+/-120 micromol min(-1...

  16. The twitch interpolation technique for study of fatigue of human quadriceps muscle

    DEFF Research Database (Denmark)

    Bülow, P M; Nørregaard, J; Mehlsen, J;

    1995-01-01

    technique. Then an endurance test was performed in which the subjects made repeated isometric contractions at 50% of the 'true' maximum torque for 4 s, separated by 6 s rest periods. During the test, the force response to single electrical stimulation (twitch amplitude) was measured at 50% and 25......The aim of the study was to examine if the twitch interpolation technique could be used to objectively measure fatigue in the quadriceps muscle in subjects performing submaximally. The 'true' maximum isometric quadriceps torque was determined in 21 healthy subject using the twitch interpolation......% of the estimated maximum torque. In 10 subjects, the test was repeated 2-4 weeks later. Twitch amplitudes at 50% of maximum torque declined exponentially with time in 20 of 21 subjects. The distribution of the exponential rate constant was skewed with a mean of 4.6 h-1 and range of 0.3-21.5 h-1. After...

  17. Changes in voluntary quadriceps activation predict changes in muscle strength and gait biomechanics following knee joint effusion.

    Science.gov (United States)

    Pietrosimone, Brian; Lepley, Adam S; Murray, Amanda M; Thomas, Abbey C; Bahhur, Nael O; Schwartz, Todd A

    2014-09-01

    It has been hypothesized that arthrogenic muscle inhibition is responsible for altering physical function following knee injury. The association between the onset of arthrogenic muscle inhibition, measured using voluntary quadriceps activation, and changes in muscle strength and gait biomechanics are unknown. Outcomes were collected before and following a 60 ml experimental knee effusion in eighteen healthy participants. Voluntary quadriceps activation was the predictor variable, while the criterion variable included, maximal voluntary isometric strength, peak knee flexion angle, peak internal knee extension moment, and peak vertical ground reaction forces during the first half of stance phase upon stair descent. Percent change scores (Δ) were imputed into linear regression equations to determine associations between predictor and criterion variables. The variance in Δ voluntary quadriceps activation significantly predicted 87% the variance in the Δ strength (R(2)=0.87, Pknee flexion angle, Δ voluntary quadriceps activation predicted an additional 29% (Δ R(2)=0.29, P=0.007) of the variance in the Δ knee extension moment (R(2)=0.54, P=0.003, Δ knee extension moment=-10.79+0.74Δ knee flexion angle+1.64Δ voluntary quadriceps activation) following knee effusion. Immediate quadriceps activation deficits following joint effusion result in immediate alterations in muscle strength, knee extensor moment and vertical ground reaction force during gait. Published by Elsevier Ltd.

  18. Muscle training with repetitive magnetic stimulation of the quadriceps in severe COPD patients.

    Science.gov (United States)

    Bustamante, Víctor; López de Santa María, Elena; Gorostiza, Amaia; Jiménez, Unai; Gáldiz, Juan B

    2010-02-01

    Previous studies have used electrical neuromuscular stimulation as a physical training method in patients with severe COPD. We introduce the use of the more tolerable magnetic stimulation for the same purpose, investigating the effectiveness of an eight-week protocol. Eighteen patients with severe COPD were randomly assigned to a magnetic stimulation training protocol, n=10, FEV(1)=30% (SD: 7) or to parallel clinical monitoring, control group, n=8, FEV(1)=35% (SD: 8). During eight weeks, patients were stimulated for 15min on each quadriceps femoris, three times per week. Quadriceps muscle strength and endurance measurements, quality-of-life questionnaires (SF36, SGRQ) and a six-minute walking test were all carried out before and after the training period in the stimulated and control subjects. All patients completed the training with increasing intensity of stimulation, displaying a significant improvement in voluntary quadriceps strength (17.5% of the baseline value) and exercise capacity, with a mean increase of 23m in the six-minute walking test. The questionnaire scores showed greater increases in quality-of-life scores in the trained subjects compared to the controls, particularly in the physical function areas: mean increments in SF36 in "physical function": +26, "role limitations due to physical problems": +40 and "vitality": +17.5, while +13, -4 and +1, respectively in controls. Saint George's "Activity" score improved by 19.6 points, for 11.5 in controls. In COPD patients who are limited due to dyspnoea, magnetic neuromuscular stimulation of the quadriceps constitutes a feasible training method for the lower limbs, with positive effects on the muscle function, effort capacity and perception areas.

  19. 'Serious thigh muscle strains': beware the intramuscular tendon which plays an important role in difficult hamstring and quadriceps muscle strains.

    Science.gov (United States)

    Brukner, Peter; Connell, David

    2016-02-01

    Why do some hamstring and quadriceps strains take much longer to repair than others? Which injuries are more prone to recurrence? Intramuscular tendon injuries have received little attention as an element in 'muscle strain'. In thigh muscles, such as rectus femoris and biceps femoris, the attached tendon extends for a significant distance within the muscle belly. While the pathology of most muscle injures occurs at a musculotendinous junction, at first glance the athlete appears to report pain within a muscle belly. In addition to the musculotendinous injury being a site of pathology, the intramuscular tendon itself is occasionally injured. These injuries have a variety of appearances on MRIs. There is some evidence that these injuries require a prolonged rehabilitation time and may have higher recurrence rates. Therefore, it is important to recognise the tendon component of a thigh 'muscle strain'.

  20. Size and composition of the calf and quadriceps muscles in Duchenne muscular dystrophy. A tomographic and histochemical study.

    Science.gov (United States)

    Jones, D A; Round, J M; Edwards, R H; Grindwood, S R; Tofts, P S

    1983-08-01

    Calf and quadriceps muscle size and composition have been examined in 5 control subjects and 12 boys (aged 7-18 years) with Duchenne muscular dystrophy using computed tomography (CT) and quantitative histochemistry of needle biopsy samples of muscle. In assessing the size of leg muscles it was found that in control subjects the muscle cross-sectional area was related to the cross-sectional area of the femur. The calf muscles in the patients were enlarged both relative to the quadriceps and absolutely when related to the cross-sectional area of the femur used as an index of stature. The enlargement of the calf was the result of accumulations of fat and connective tissue in the presence of relatively normal (compared to femur size) amounts of muscle tissue. Although hypertrophied muscle fibres were a feature of the biopsy samples in the calf the extent of this was insufficient to contribute appreciably to the total muscle enlargement.

  1. Quadriceps and respiratory muscle fatigue following high-intensity cycling in COPD patients.

    Directory of Open Access Journals (Sweden)

    Damien Bachasson

    Full Text Available Exercise intolerance in COPD seems to combine abnormal ventilatory mechanics, impaired O2 transport and skeletal muscle dysfunction. However their relative contribution and their influence on symptoms reported by patients remain to be clarified. In order to clarify the complex interaction between ventilatory and neuromuscular exercise limiting factors and symptoms, we evaluated respiratory muscles and quadriceps contractile fatigue, dynamic hyperinflation and symptoms induced by exhaustive high-intensity cycling in COPD patients. Fifteen gold II-III COPD patients (age = 67 ± 6 yr; BMI = 26.6 ± 4.2 kg.m(-2 performed constant-load cycling test at 80% of their peak workload until exhaustion (9.3 ± 2.4 min. Before exercise and at exhaustion, potentiated twitch quadriceps strength (Q(tw, transdiaphragmatic (P(di,tw and gastric (P(ga,tw pressures were evoked by femoral nerve, cervical and thoracic magnetic stimulation, respectively. Changes in operational lung volumes during exercise were assessed via repetitive inspiratory capacity (IC measurements. Dyspnoea and leg discomfort were measured on visual analog scale. At exhaustion, Q(tw (-33 ± 15%, >15% reduction observed in all patients but two and Pdi,tw (-20 ± 15%, >15% reduction in 6 patients were significantly reduced (P15% reduction in 3 patients. Percentage reduction in Q(tw correlated with the percentage reduction in P(di,tw (r = 0.66; P<0.05. Percentage reductions in P(di,tw and P(ga,tw negatively correlated with the reduction in IC at exhaustion (r = -0.56 and r = -0.62, respectively; P<0.05. Neither dyspnea nor leg discomfort correlated with the amount of muscle fatigue. In conclusion, high-intensity exercise induces quadriceps, diaphragm and less frequently abdominal contractile fatigue in this group of COPD patients. In addition, the rise in end-expiratory lung volume and diaphragm flattening associated with dynamic hyperinflation in COPD might limit the development of abdominal and

  2. EFFECT OF TREADMILL TRAINING ON QUADRICEPS AND HAMSTRING MUSCLES STRENGTH IN CHILDREN WITH KNEE HEAMARTHROSIS

    Directory of Open Access Journals (Sweden)

    Amira Mahmoud Abd-Elmonem,

    2014-08-01

    Full Text Available Background: Heamarthrosis is the most disabling complication of hemophilia causing pain, swelling, limited joint range, and weakness. Without appropriate treatment, chronic heamarthrosis remains a serious problem with permanent disability. The Purpose of this work was to study the effect of treadmill training on quadriceps and hamstring muscles strength in children with knee heamarthrosis. Material and methods: Thirty hemophilic male children with unilateral knee heamarthrosis, their ages ranged from 8 to 12 years. They were divided randomly into two groups in equal numbers, control (A and study (B, 15 patients each. Both groups received traditional treatment program for one hour 5 days / weak, in addition the study group received treadmill training for 15 minutes. Peak torque of quadriceps and hamstring muscles was measured by Biodex Isokinetic Dynamometer. Knee swelling was measured by tape measurement. Assessment was performed before and after three successive months of treatment. Results: The results revealed significant difference in all tested variables (p<0.05 after three months of treatment in both groups in favor to the study group. Conclusion: Treadmill training is beneficial in increasing muscle strength and reducing joint swelling in children with knee heamarthrosis.

  3. A rare case of aberrant quadriceps muscle anatomy preventing anterolateral thigh flap harvest

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    Eugene Omakobia

    2016-03-01

    Full Text Available The anterolateral thigh (ALT flap is now widely established as a versatile flap which can provide ample amounts of skin, muscle and fascia to construct a variety of defects following major head and neck surgery. However, its use remains cautious due to well documented variations in its vascular anatomy for which this flap is notorious. What is less well known is the effect of variations in quadriceps muscle anatomy on the success of flap harvest. Here, we report a unique case in which fusion of the vastus intermedius (V.I and vastus lateralis (V.L muscles precluded ALT flap harvest. We also advise on appropriate management should similar cases be encountered. To our knowledge this is the first reported case of its kind in the English language literature.

  4. Effect of Quadriceps Exercise Training on Muscle Fiber Angle in Patients With Patellofemoral Pain Syndrome

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    Honarpishe

    2015-10-01

    Full Text Available Background Imbalance between the vastus medialis oblique (VMO muscle and the vastus lateralis oblique (VTO Vastus lateralis has been thought to be a primary cause of abnormal patellar tracking, possibly leading to patellofemoral pain syndrome (PFPS. Objectives The purpose of this study was to investigate the effect of quadriceps muscle strengthening exercises on the ratio of VMO to VL oblique and longus muscle fiber angles. Patients and Methods Thirty-five subjects (23 females and 12 males, mean age 26.6 years ± 1.1 SD with PFPS were randomized into an exercise group or a control group. The exercise group performed knee extension exercises for four weeks based on the Kaya exercise program (three times per week, while the control group received no treatment. Measurements included knee extensor concentric and eccentric muscle torque using a Biodex isokinetic machine and the fiber angle of the VMO, VL oblique and longus muscles using ultrasonography, all of which were evaluated at the time of the initial examination and at the end of the four-week period. Results There were no significant differences in the muscle strength and fiber angle of the VMO, VL oblique and longus muscles after training between the control and experimental groups (P > 0.05. Conclusions The study findings indicate that short-term exercises had no significant effect on the ratio of VMO to VL muscle fiber angles in patients with PFPS.

  5. Quadriceps muscle weakness and atrophy are associated with a differential epigenetic profile in advanced COPD.

    Science.gov (United States)

    Puig-Vilanova, Ester; Martínez-Llorens, Juana; Ausin, Pilar; Roca, Josep; Gea, Joaquim; Barreiro, Esther

    2015-06-01

    Epigenetic mechanisms regulate muscle mass and function in models of muscle dysfunction and atrophy. We assessed whether quadriceps muscle weakness and atrophy are associated with a differential expression profile of epigenetic events in patients with advanced COPD (chronic obstructive pulmonary disease). In vastus lateralis (VL) of sedentary severe COPD patients (n=41), who were further subdivided into those with (n=25) and without (n=16) muscle weakness and healthy controls (n=19), expression of muscle-enriched miRNAs, histone acetyltransferases (HATs) and deacetylases (HDACs), growth and atrophy signalling markers, total protein and histone acetylation, transcription factors, small ubiquitin-related modifier (SUMO) ligases and muscle structure were explored. All subjects were clinically evaluated. Compared with controls, in VL of all COPD together and in muscle-weakness patients, expression of miR-1, miR-206 and miR-27a, levels of lysine-acetylated proteins and histones and acetylated histone 3 were increased, whereas expression of HDAC3, HDAC4, sirtuin-1 (SIRT-1), IGF-1 (insulin-like growth factor-1) were decreased, Akt (v-akt murine thymoma viral oncogene homologue 1) expression did not differ, follistatin expression was greater, whereas myostatin expression was lower, serum reponse factor (SRF) expression was increased and fibre size of fast-twitch fibres was significantly reduced. In VL of severe COPD patients with muscle weakness and atrophy, epigenetic events regulate muscle differentiation rather than proliferation and muscle growth and atrophy signalling, probably as feedback mechanisms to prevent those muscles from undergoing further atrophy. Lysine-hyperacetylation of histones may drive enhanced protein catabolism in those muscles. These findings may help design novel therapeutic strategies (enhancers of miRNAs promoting myogenesis and acetylation inhibitors) to selectively target muscle weakness and atrophy in severe COPD.

  6. [Bilateral dysfunction of the quadriceps muscle after unilateral cruciate ligament rupture with concomitant injury central activation deficit].

    Science.gov (United States)

    Urbach, D; Nebelung, W; Röpke, M; Becker, R; Awiszus, F

    2000-11-01

    The aim of the study was to investigate the ability to activate the quadriceps femoris muscle voluntarily in patients after severe knee injuries and it's influence on muscle function. 33 male patients after ACL-rupture with concomitant injuries were investigated with a twitch-interpolation-method to determine the maximal voluntary contraction force (MVC) and the ability to activate the quadriceps muscle voluntarily. The results were compared to a previously investigated group of patients after isolated ACL-rupture and to an aged-matched control group. The patients with extensive knee injuries presented a significant higher deficit of voluntary quadriceps muscle activation on the injured (78.8 +/- 2.09%, mean +/- SEM) and equally on the uninjured side (78.9 +/- 1.91%) compared to the patients after isolated ACL-rupture and to controls. A minor MVC-deficit of the patients quadriceps muscle of the uninjured side could be explained by the voluntary activation deficit alone, the major MVC deficit of the injured side by muscle atrophy and a voluntary activation deficit. The activation deficit is probably the underlying reason for persisting muscle wasting and [not readable: see text

  7. Changes in Quadriceps Muscle Thickness, Disease Severity, Nutritional Status, and C-Reactive Protein after Acute Stroke.

    Science.gov (United States)

    Nozoe, Masafumi; Kanai, Masashi; Kubo, Hiroki; Kitamura, Yuka; Yamamoto, Miho; Furuichi, Asami; Takashima, Sachie; Mase, Kyoshi; Shimada, Shinichi

    2016-10-01

    Lower leg muscle wasting is common in stroke patients; however, patient characteristics in the acute phase are rarely studied. This study aimed to examine the relationship between changes in quadriceps muscle thickness and disease severity, nutritional status, and C-reactive protein (CRP) levels after acute stroke. Thirty-one consecutive patients with acute intracerebral hemorrhage or ischemic stroke had quadriceps muscle thickness measured in the paretic and nonparetic limbs within 1 week after admission (first week) and 2 weeks after the first examination (last week) using ultrasonography. We also determined the relationship between the percentage change in muscle thickness and disease severity, nutritional status, and CRP levels on admission. There was a significant correlation between changes in muscle thickness for both paretic and nonparetic sides and National Institutes of Health Stroke Scale (NIHSS) scores (paretic limb: r = -.46, P = .01; nonparetic limb: r = -.54, P = .002, respectively); however, there was no significant correlation with nutritional status on admission. Quadriceps muscle thickness was reduced more in the CRP-positive (≥.3 mg/dL) patients than in the CRP-negative (stroke. Nutritional status on admission was not correlated with changes in quadriceps muscle thickness for these patients. Copyright © 2016 National Stroke Association. Published by Elsevier Inc. All rights reserved.

  8. Effect of endurance versus resistance training on quadriceps muscle dysfunction in COPD: a pilot study

    Directory of Open Access Journals (Sweden)

    Iepsen UW

    2016-10-01

    Full Text Available Ulrik Winning Iepsen,1 Gregers Druedal Wibe Munch,1 Mette Rugbjerg,1 Anders Rasmussen Rinnov,1 Morten Zacho,1 Stefan Peter Mortensen,1,2 Niels H Secher,3 Thomas Ringbaek,4 Bente Klarlund Pedersen,1 Ylva Hellsten,5 Peter Lange,1,4,6 Pia Thaning1,4 1The Centre of Inflammation and Metabolism and the Centre for Physical Activity Research, Rigshospitalet, University of Copenhagen, Denmark, 2Department of Cardiovascular and Renal Research, University of Southern Denmark, Odense, 3Department of Anesthesiology, University of Copenhagen, Rigshospitalet, Copenhagen, 4Department of Respiratory Medicine, University Hospital Hvidovre, Hvidovre, 5Department of Nutrition, Exercise and Sports, University of Copenhagen, 6Department of Public Health, Section of Social Medicine, University of Copenhagen, Copenhagen, Denmark Introduction: Exercise is an important countermeasure to limb muscle dysfunction in COPD. The two major training modalities in COPD rehabilitation, endurance training (ET and resistance training (RT, may both be efficient in improving muscle strength, exercise capacity, and health-related quality of life, but the effects on quadriceps muscle characteristics have not been thoroughly described.Methods: Thirty COPD patients (forced expiratory volume in 1 second: 56% of predicted, standard deviation [SD] 14 were randomized to 8 weeks of ET or RT. Vastus lateralis muscle biopsies were obtained before and after the training intervention to assess muscle morphology and metabolic and angiogenic factors. Symptom burden, exercise capacity (6-minute walking and cycle ergometer tests, and vascular function were also assessed.Results: Both training modalities improved symptom burden and exercise capacity with no difference between the two groups. The mean (SD proportion of glycolytic type IIa muscle fibers was reduced after ET (from 48% [SD 11] to 42% [SD 10], P<0.05, whereas there was no significant change in muscle fiber distribution with RT. There was

  9. A Study on the Results of Reconstructing Posterior Cruciate Ligament Using Graft from Quadriceps Muscle Tendon

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    K Nazem

    2004-06-01

    Full Text Available Background: Many of the knees affected by rupture of the posterior cruciate ligament (PCL lack their desirable function. Researchers are currently seeking surgical procedures for treating PCL rupture, which can offer a reliable degree of objective and subjective knee stability after surgery. This study assesses the results of anatomical reconstruction of PCL using graft from the tendon of the quadriceps muscle. Methods: This is a descriptive prospective study involving 14 patients with clinical diagnosis of PCL rupture. The patients complained of knee discomfort in spite of conservative treatment and many sessions of physiotherapy. Subjective symptoms of knee instability, i.e. giving way, pain after long walks and pain during climbing, as well as objective knee instability symptoms as assessed by posterior drawer test at 30° and 90° knee flexion, and neutral rotation were recorded and compared prior to and after surgery. The procedure entailed anatomical reconstruction of PCL using grafts taken from the tendon of quadriceps muscle and part of proximal patella. Results: Two patients were excluded from the study due to their failure to refer for follow-up. The patients included 11 men and 1 woman with a mean age of 23 years. The patients displayed statistically significant improvement after surgery as regards subjective symptoms, i.e. giving way, pain after long walks and pain in climbing. Objective knee instability symptoms as evaluated by posterior drawer test at 30° and 90° knee flexion and neutral rotation also showed significant improvement compared to pre-operation findings. Conclusion: Reconstruction of PCL is aimed at achieving normal knee kinematics and stability. The procedure used in this study entailed anatomical reconstruction of PCL. Given the objective and subjective results obtained, the use of this procedure is recommended by authors as the method of choice for reconstructing PCL. Keywords: Posterior Cruciate Ligament, Knee

  10. Sex differences in function and structure of the quadriceps muscle in chronic obstructive pulmonary disease patients.

    Science.gov (United States)

    Ausín, Pilar; Martínez-Llorens, Juana; Sabaté-Bresco, Marina; Casadevall, Carme; Barreiro, Esther; Gea, Joaquim

    2016-12-06

    Chronic obstructive pulmonary disease (COPD) is a complex disorder with extrapulmonary manifestations. Even though there is some knowledge regarding sex differences in the lung disease, little is known about extrapulmonary manifestations. Our aim was to analyze the specific profile of muscle dysfunction, structure, and biology in COPD women. Twenty-one women and 19 men with stable COPD as well as 15 controls were included. Nutritional status, physical activity, lung and muscle function, exercise capacity, and quality of life were assessed. In addition, blood, breath condensate, and quadriceps muscle samples were tested for inflammatory markers. Moreover, fiber phenotype, signs of damage-regeneration, and the expression of key genes linked to myogenesis and inflammation were assessed in the muscle. Inflammatory markers were increased in all body compartments but no correlation was found among them. Muscle dysfunction was present in both COPD groups but was more marked in women. The opposite occurred with the increase in the percentage of type II fibers that was lower in women despite a similar level of airway obstruction as in men. Female COPD also showed higher signs of muscle damage than COPD men who, in contrast, exhibited slightly higher signs of regeneration. We conclude that sex influences muscle phenotype and function in COPD.

  11. Differential Glucose Uptake in Quadriceps and Other Leg Muscles During One-Legged Dynamic Submaximal Knee-Extension Exercise

    OpenAIRE

    Kalliokoski, Kari K.; Boushel, Robert; Langberg, Henning; Scheede-Bergdahl, Celena; Ryberg, Ann Kathrine; Døssing, Simon; Kjær, Andreas; Kjær, Michael

    2011-01-01

    One-legged dynamic knee-extension exercise (DKE) is a widely used model to study the local cardiovascular and metabolic responses to exercise of the quadriceps muscles. In this study, we explored the extent to which different muscles of the quadriceps are activated during exercise using positron emission tomography (PET) determined uptake of [18F]-fluoro-deoxy-glucose (GU) during DKE. Five healthy male subjects performed DKE at 25 W for 35 min and both the contracting and contralateral restin...

  12. Static vs. Dynamic Acute Stretching Effect on Quadriceps Muscle Activity during Soccer Instep Kicking.

    Science.gov (United States)

    Amiri-Khorasani, Mohammadtaghi; Kellis, Eleftherios

    2013-12-18

    The purpose of this study was to compare the effects of static and dynamic stretching on quadriceps muscle activation during maximal soccer instep kicking. The kicking motion of twelve male college soccer players (body height: 174.66 ± 5.01 cm; body mass: 72.83 ± 4.83 kg; age: 18.83 ± 0.75 years) was captured using six synchronized high-speed infra-red cameras whilst electromyography (EMG) signals from vastus medialis (VM), lateralis (VL) and rectus femoris (RF) were recorded before and after static or dynamic stretching. Analysis of variance designs showed a higher increase in knee extension angular velocity (9.65% vs. -1.45%, p vs. -8.33%, p vs. -12%, p vs. -6.67%, p dynamic stretching exercises. Based on these results, it could be suggested that dynamic stretching is probably more effective in increasing quadriceps muscle activity and knee extension angular velocity during the final swing phase of a maximal soccer instep kick than static stretching.

  13. Preactivation of the quadriceps muscle could limit cranial tibial translation in a cranial cruciate ligament deficient canine stifle.

    Science.gov (United States)

    Ramirez, Juan M; Lefebvre, Michael; Böhme, Beatrice; Laurent, Cédric; Balligand, Marc

    2015-02-01

    Cranial cruciate ligament (CrCL) deficiency is the leading cause of lameness of the canine stifle. Application of tension in the quadriceps muscle could trigger cranial tibial translation in case of CrCL rupture. We replaced the quadriceps muscle and the gastrocnemius muscle by load cells and turn-buckles. First, eight canine limbs were placed in a servo-hydraulic testing machine, which applied 50% of body weight (BW). In a second phase, the CrCL was transected, and the limbs were tested in a similar manner. In a third phase, a quadriceps pretension of 15% BW was applied and limbs were again tested in a similar manner. Cranial tibial translation was significantly decreased in CrCL deficient stifles (p quadriceps pretension was applied. These findings indicate that quadriceps pretension could play a role in the stability of a CrCL deficient stifle and should then be considered in rehabilitation programs and conservative treatment of CrCL rupture in dogs.

  14. Angle- and gender-specific quadriceps femoris muscle recruitment and knee extensor torque.

    Science.gov (United States)

    Pincivero, Danny M; Salfetnikov, Yuliya; Campy, Robert M; Coelho, Alan J

    2004-11-01

    The objectives were to examine knee angle-, and gender-specific knee extensor torque output and quadriceps femoris (QF) muscle recruitment during maximal effort, voluntary contractions. Fourteen young adult men and 15 young adult women performed three isometric maximal voluntary contractions (MVC), in a random order, with the knee at 0 degrees (terminal extension), 10 degrees, 30 degrees, 50 degrees, 70 degrees, and 90 degrees flexion. Knee extensor peak torque (PT), and average torque (AT) were expressed in absolute (N m), relative (N m kg(-1)) and allometric-modeled (N m kg(-n)) units. Vastus medialis (VM), vastus lateralis (VL), and rectus femoris (RF) muscle EMG signals were full-wave rectified and integrated over the middle 3 s of each contraction, averaged over the three trials at each knee angle, and normalized to the activity recorded at 0 degrees. Muscle recruitment efficiency was calculated as the ratio of the normalized EMG of each muscle to the allometric-modeled average torque (normalized to the values at 0 degrees flexion), and expressed as a percent. Men generated significantly greater knee extensor PT and AT than women in absolute, relative and allometric-modeled units. Absolute and relative PT and AT were significantly highest at 70 degrees, while allometric-modeled values were observed to increase significantly across knee joint angles 10-90 degrees. VM EMG was significantly greater than the VL and RF muscles across all angles, and followed a similar pattern to absolute knee extensor torque. Recruitment efficiency improved across knee joint angles 10-90 degrees and was highest for the VL muscle. VM recruitment efficiency improved more than the VL and RF muscles across 70-90 degrees flexion. The findings demonstrate angle-, and gender-specific responses of knee extensor torque to maximal-effort contractions, while superficial QF muscle recruitment was most efficient at 90 degrees, and less dependent on gender.

  15. Sports Mass Age Therapy on the Reduction of Delayed Onset Muscle Soreness of the Quadriceps Femoris

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    Boguszewski Dariusz

    2014-12-01

    Full Text Available Purpose. Massage therapy is one of most commonly applied treatments during athletic training. The aim of this study was to assess the effectiveness of sports massage therapy on reducing post-exercise quadriceps muscle soreness. Methods. A sample of 29 women aged 24-26 years was divided into an experimental group (n = 15 receiving classic sports massage therapy and a control group (n = 14 given no treatment. An exercise session consisting of five sets of deep squat jumps was administered after which lower limb power as assessed via the vertical jump test. Muscle soreness was assessed using the visual analogue scale (VAS and exercise intensity with the Borg Rating of Perceived Exertion Scale. Subsequent measurements of lower limb power and muscle soreness were performed 24, 48, 72 and 96 h after the exercise session. Differences between the measurements were assessed by the Friedman and least significant difference tests while between-group comparisons involved the Mann-Whitney U test. Results. The largest decrease in lower limb power was observed between the first measurement after the exercise session and 24 h later (p < 0.01. The smallest decrease in power was observed in the massage group. The highest levels of muscle soreness were noted 24 h post-exercise in the massage group and 48 h post-exercise in the control group. The experimental group showed a decrease in muscle soreness in each subsequent measurement, with the results close to zero on the VAS 96 h postexercise. Conclusions. Massage therapy quickened recovery and improved muscle efficiency post-exercise and may serve as an effective treatment of muscle soreness. The analgesic effect of massage suggests it should be widely applied in sport, physical therapy and rehabilitation.

  16. EFFECT OF SOCCER TRAINER AND ELASTIC BAND ON QUADRICEPS FEMORIS MUSCLE STRENGTH IN YOUNG HEALTHY INDIVIDUALS: A RANDOMIZED CONTROLLED TRIAL

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    Santosh Metgud

    2015-06-01

    Full Text Available Introduction: Quadriceps is one of the strongest muscle of the body that is required for knee mobility. Quadriceps plays a crucial role in many daily activities such as walking, twisting, running, jumping, and controlling the movement of knee. Since it’s a two joint muscle, they tend to become very to tight leading to imbalance, which can give rise to a number of postural problems and common musculoskeletal disorder causing pain in the knee joint. It could be acute, subacute and chronic in its clinical presentation. Hence strengthening of quadriceps femoris is necessary. Materials and Methods: a total of 90 participants within age of 21 to 29 years and BMI 19.9 to 24.9 having no neurological, cardiopulmonary and musculoskeletal disease were selected. Results: of the total 90 subjects, the mean age of the participants in group A 21.67±0.88 the mean age of participants in group B was 22.23±1.33 and the mean age of participants in the group C was 22.03±1.27. The result showed high significance in the group B. Conclusion: the study showed increase in the quadriceps muscle strength in group B.

  17. Postural response to vibration of triceps surae, but not quadriceps muscles, differs between people with and without knee osteoarthritis.

    Science.gov (United States)

    Shanahan, Camille J; Wrigley, Tim V; Farrell, Michael J; Bennell, Kim L; Hodges, Paul W

    2014-08-01

    Although proprioceptive impairments are reported in knee osteoarthritis (OA), there has been little investigation of the underlying causes. Muscle spindles make an important contribution to proprioception. This study investigated whether function of quadriceps, triceps surae, and tibialis anterior muscle spindles is altered in individuals with knee OA. Thirty individuals with knee OA (17 females, 66 ± 7 [mean ± SD] years) and 30 healthy asymptomatic controls (17 females, 65 ± 8 years) stood comfortably and blindfolded on a force plate. Mechanical vibration (60 Hz) was applied bilaterally over the quadriceps, triceps surae, or tibialis anterior muscles for the middle 15 s (Vibration) of a 45 s trial (preceded and followed by 15 s Baseline and Recovery periods). Two trials were recorded for each muscle site. Mean anterior-posterior displacement of centre of pressure was analysed. Although there were no differences between groups for trials with vibration applied to the quandriceps or tibialis anterior, participants with knee OA were initially perturbed more by triceps surae vibration and accommodated less to repeated exposure than controls. This indicates that people with knee OA have less potential to detect or compensate for disturbed input to triceps surae, possibly due to an inability to compensate using muscles spindles in the quadriceps muscle.

  18. Aerobic metabolism of human quadriceps muscle: in vivo data parallel measurements on isolated mitochondria

    DEFF Research Database (Denmark)

    Rasmussen, Ulla Fugmann; Rasmussen, Hans N.; Krustrup, Peter

    2001-01-01

    The aim of the present study was to examine whether parameters of isolated mitochondria could account for the in vivo maximum oxygen uptake ( O2 max) of human skeletal muscle. O2 max and work performance of the quadriceps muscle of six volunteers were measured in the knee extensor model (range 10......-18 mmol O2 · min 1 · kg 1 at work rates of 22-32 W/kg). Mitochondria were isolated from the same muscle at rest. Strong correlations were obtained between O2 max and a number of mitochondrial parameters (mitochondrial protein, cytochrome aa3, citrate synthase, and respiratory activities). The activities...... of citrate synthase, succinate dehydrogenase, and pyruvate dehydrogenase, measured in isolated mitochondria, corresponded to, respectively, 15, 3, and 1.1 times the rates calculated from O2 max. The respiratory chain activity also appeared sufficient. Fully coupled in vitro respiration, which is limited...

  19. The quadriceps muscle of knee joint modelling Using Hybrid Particle Swarm Optimization-Neural Network (PSO-NN)

    Science.gov (United States)

    Kamaruddin, Saadi Bin Ahmad; Marponga Tolos, Siti; Hee, Pah Chin; Ghani, Nor Azura Md; Ramli, Norazan Mohamed; Nasir, Noorhamizah Binti Mohamed; Ksm Kader, Babul Salam Bin; Saiful Huq, Mohammad

    2017-03-01

    Neural framework has for quite a while been known for its ability to handle a complex nonlinear system without a logical model and can learn refined nonlinear associations gives. Theoretically, the most surely understood computation to set up the framework is the backpropagation (BP) count which relies on upon the minimization of the mean square error (MSE). However, this algorithm is not totally efficient in the presence of outliers which usually exist in dynamic data. This paper exhibits the modelling of quadriceps muscle model by utilizing counterfeit smart procedures named consolidated backpropagation neural network nonlinear autoregressive (BPNN-NAR) and backpropagation neural network nonlinear autoregressive moving average (BPNN-NARMA) models in view of utilitarian electrical incitement (FES). We adapted particle swarm optimization (PSO) approach to enhance the performance of backpropagation algorithm. In this research, a progression of tests utilizing FES was led. The information that is gotten is utilized to build up the quadriceps muscle model. 934 preparing information, 200 testing and 200 approval information set are utilized as a part of the improvement of muscle model. It was found that both BPNN-NAR and BPNN-NARMA performed well in modelling this type of data. As a conclusion, the neural network time series models performed reasonably efficient for non-linear modelling such as active properties of the quadriceps muscle with one input, namely output namely muscle force.

  20. Influence of Isometric Exercise Training on Quadriceps Muscle Architecture and Strength in Obese Subjects with Knee Osteoarthritis

    Directory of Open Access Journals (Sweden)

    Waleed S Mahmoud

    2017-03-01

    Full Text Available Obese individuals have reduced quadriceps muscle strength relative to body mass that may increase the rate of progression of knee osteoarthritis (OA. The purpose of this study was to evaluate the effects of isometric exercise training on quadriceps muscle architecture and strength in obese subjects with knee osteoarthritis. Methods: Fortyfour obese male subjects aged 40–65 years diagnosed with knee osteoarthritis were randomly assigned into group A (n=32 and group B (n=12. Group A subjects performed a 12-week isometric exercise program. Group B subjects did not participate in any exercise program and maintained their ordinary activities for the same period. Both groups received the same conventional physical therapy program including hot packs and therapeutic ultrasonic. Muscle thickness, pennation angles and fascicle length of the vastus lateralis (VL muscle of the affected knee were measured at rest by B-mode ultrasonography. Maximal voluntary isometric knee extension torque (MVIC of the affected knee was measured using an isokinetic dynamometer. Knee pain and function were evaluated using visual analogue pain scale (VAS and Western Ontario and McMaster Universities Arthritis Index (WOMAC. All variables were evaluated before and the end of the intervention period for both groups. Results: at the end of the program, group A subjects showed significant improvements compared with group B subjects regarding MVIC and muscle architecture parameters (p<0.05. Also, there was significant improvement in post-test VAS and WOMAC scores in group A subjects compared to group B subjects (p<0.05. Conclusion: A 12-week quadriceps isometric training program improves knee pain and quadriceps muscle strength and architecture in obese subjects with knee OA. These results indicate that isometric training should be regarded as a proper exercise intervention for obese patients with knee OA.

  1. Relationship between quadriceps femoris muscle volume and muscle torque at least 18 months after anterior cruciate ligament reconstruction.

    Science.gov (United States)

    Konishi, Y; Oda, T; Tsukazaki, S; Kinugasa, R; Fukubayashi, T

    2012-12-01

    The purpose of this study was to evaluate motor unit recruitment in the quadriceps femoris (QF) after anterior cruciate ligament (ACL) rupture and repair. Subjects included 24 patients at ≥ 18 months after ACL reconstruction and 22 control subjects with no history of knee injury. A series of cross-sectional magnetic resonance images were obtained to compare the QF of patients' injured side with that of their uninjured sides and that of uninjured control subjects. Muscle torque per muscle volume was calculated as isokinetic peak torque divided by QF muscle volume (cm(3)). The mean muscle torque per unit volume of the injured side of patients was not significantly different from that of the uninjured side or control subjects (one-way ANOVA) Results of the present study were contrary to the results of a previous study that evaluated patients at ≤ 12 months after ACL reconstruction. The present study found that high-threshold motor unit recruitment was restored at ≥ 18 months after ACL reconstruction. Thus, clinicians must develop techniques that increase the recruitment of high-threshold motor units in the QF from the period immediately after the injury until approximately 18 months after ACL reconstruction.

  2. The impact of foot position on electromyographical activity of the superficial quadriceps muscles during leg extension.

    Science.gov (United States)

    Stoutenberg, Mark; Pluchino, Alessandra P; Ma, Fangchao; Hoctor, Jennifer E; Signorile, Joseph F

    2005-11-01

    This study investigated variations in electromyographic (EMG) responses of the vastus lateralis (VL), rectus femoris (RF), and vastus medialis (VM) due to foot position during leg extension. Twenty-four men and women (23.67 +/= 4.02 years) performed 8 repetitions at 70% of 8 repetition maximum with their leg medially rotated, laterally rotated, and neutral. Repeated-measures analyses of variance indicated that the highest normalized root mean square (NrmsEMG) for the VM and VL occurred with medial rotation, and the highest NrmsEMG for the RF occurred with lateral rotation. Significant NrmsEMG increases and median power frequency decreases occurred across repetitions regardless of foot position. Therefore, medial rotation produced the greatest muscle activation for the VL and VM, whereas lateral rotation produced the greatest activation in the RF. These findings are applicable to athletes or bodybuilders who are seeking to selectively increase either the size or performance of a specific muscle of the quadriceps group.

  3. Hamstrings-to-quadriceps strength and size ratios of male professional soccer players with muscle imbalance.

    Science.gov (United States)

    Denadai, Benedito Sérgio; de Oliveira, Felipe Bruno Dias; Camarda, Sérgio Ricardo de Abreu; Ribeiro, Leandro; Greco, Camila Coelho

    2016-03-01

    The aim of this study was to determine the correlation between the concentric hamstrings/quadriceps muscle strength (Hcon :Qcon ) and cross-sectional area ratios (Hcsa :Qcsa ) in professional soccer players with Hcon :Qcon imbalance. Nine male professional soccer players (25·3 ± 4·1 years) performed five maximal concentric contractions of the knee extensors (KE) and flexors (KF) at 60 s(-1) to assess Hcon :Qcon . The test was performed using the dominant (preferred kicking), and non-dominant limb with a 5-min recovery period was allowed between them. Only players with Hcon :Qcon muscle cross-sectional area (CSA) of KE and KF was determined by magnetic resonance imaging. The correlations between Hcon :Qcon and Hcsa :Qcsa in the dominant leg (r = -0·33), non-dominant leg (r = 0·19) and in the both legs combined (r = 0·28) were not statistically significant (P>0·05). Thus, the Hcon :Qcon seems not to be determined by Hcsa :Qcsa in professional soccer players with Hcon :Qcon imbalance.

  4. Kinesiology Tape does not Affect Serum Creatine Kinase Level and Quadriceps Activity during Recovery from Delayed-Onset Muscle Soreness

    Directory of Open Access Journals (Sweden)

    Naoko Aminaka

    2017-01-01

    Full Text Available Background: Delayed-onset muscle soreness (DOMS causes muscle damage and edema that can hinder performance and increase risks for secondary injuries. Kinesiology Tape (KT may be an effective modality for aiding in recovery, however, no study has investigated the effects of KT on the physiological biomarkers such as serum creatine kinase (CK level, concurrently with measures of performance and function, during recovery from DOMS. Objective: Investigate the effects of KT on serum CK level, electromyographic (EMG activity of the quadriceps muscles, and performances of countermovement jump (CMJ and triple single-leg hop for distance (HopD during recovery from DOMS. Method: Fifty-eight healthy college-age participants were randomly assigned to KT (n=15, placebo (n=19, and control (n=24 groups. Serum CK level and quadriceps EMG activity and performance during CMJ and HopD were collected at baseline, immediately after repetitive eccentric quadriceps exercise, 48 hours, and 72 hours post-exercise. The EMG recording of rectus femoris, vastus medialis, and vastus lateralis during the CMJ and HopD were normalized to the baseline maximum voluntary isometric contraction. Results: A significant main effect of time on the serum CK level, EMG activity, and performance (p0.05. Conclusion: Taping interventions did not improve the serum CK level or muscle activity and performance during recovery from DOMS. Kinesiology tape may not be the first choice of method for enhancing recovery from DOMS in otherwise healthy individuals.

  5. Effect of triceps surae and quadriceps muscle fatigue on the mechanics of landing in stepping down in ongoing gait.

    Science.gov (United States)

    Barbieri, F A; Gobbi, L T B; Lee, Y J; Pijnappels, M; van Dieën, J H

    2014-01-01

    The aim of this study was to evaluate the effects of muscle fatigue of triceps surae and quadriceps muscles in stepping down in ongoing gait. We expected that the subjects would compensate for muscle fatigue to prevent potential loss of balance in stepping down. A total of 10 young participants walked over a walkway at a self-selected velocity to step down a height difference of 10-cm halfway. Five trials were performed before and after a muscle fatigue protocol. Participants performed two fatigue protocols: one for ankle muscle fatigue and another for knee muscle fatigue. Kinematics of and ground reaction forces on the leading leg were recorded. Fatigue did not cause a change in the frequency of heel or toe landing. Our results indicate that in stepping down fatigue effects are compensated by redistributing work to unfatigued muscle groups and by gait changes aimed at enhancing balance control, which was however only partially successful.

  6. Heterogeneous recruitment of quadriceps muscle portions and fibre types during moderate intensity knee-extensor exercise: effect of thigh occlusion

    DEFF Research Database (Denmark)

    Krustrup, Peter; Söderlund, Karin; Relu, Mihai U.;

    2009-01-01

    The involvement of quadriceps femoris muscle portions and fibre type recruitment was studied during submaximal knee-extensor exercise without and with thigh occlusion (OCC) and compared with responses during intense exercise. Six healthy male subjects performed 90-s of moderate exercise without...... (MOD; 29+/-4 W) and with thigh OCC, and moderate exercise followed by 90-s of intense exercise (HI; 65+/-8 W). Temperatures were continuously measured in m. vastus lateralis (VL), vastus medialis (VM) and rectus femoris (RF) and successive muscle biopsies were obtained from VL. During MOD, muscle...

  7. The effects of gender on quadriceps muscle activation strategies during a maneuver that mimics a high ACL injury risk position.

    Science.gov (United States)

    Myer, Gregory D; Ford, Kevin R; Hewett, Timothy E

    2005-04-01

    While the increased incidence of serious knee injuries in female athletes is well established, the underlying neuromuscular mechanisms related to the elevated ACL injury rate has yet to be delineated. Video analysis of ACL injury during competitive sports play indicates a common body position associated with non-contact ACL injury; the tibia is externally rotated, the knee is close to full extension, the foot is planted and as the limb is decelerated it collapses into valgus. The purpose of the current prospective study was to evaluate gender differences in quadriceps muscle activation strategies when performing a physically challenging, but reproducible maneuver that mimics the high ACL injury risk position (in the absence of high velocity and high loads). Twenty physically active college-aged subjects (10 male and 10 female) performed multiple sets of the prescribed exercise. EMG recordings were employed to measure the ratio of activation between the medial and lateral quadriceps during the 4, 8, 12, 16, and 20th sets of exercise. Females demonstrated decreased RMS medial-to-lateral quadriceps ratios compared to males (F(1,18)=5.88, p=0.026). There was no main effect of set number on RMS quadriceps ratio (p>0.05). The results of this study suggest that females utilize neuromuscular activation strategies which may contribute to "dynamic valgus" and ACL rupture when performing high-risk maneuvers.

  8. Progressive fibrosis of the quadriceps muscle FIBROSIS PROGRESIVA DEL CUÁDRICEPS

    Directory of Open Access Journals (Sweden)

    Enrique Vergara-Amador

    2011-06-01

    Full Text Available Background. Fibrosis of the quadriceps in children is a frequently reported pathology which is associated with antibiotics having been injected into the thigh. This study presents a series of patients having a common background of having had a single pentavalent vaccine dose or injectable vitamin K and presenting progressive fibrosis of the quadriceps muscle. Materials and methods. Seven children were found who had progressive unilateral retraction of the knee. Six of them had a background of a single dose of vaccine having been given when they were four months old, suffering muscle contractions/spasms 4 to 8 weeks after the application; one child had been given vitamin K when born. Results. Magnetic resonance revealed alterations in the intermediate vastus medialis obliquus (VMO without intra-articular pathology. Average age when surgery was performed was 18 months (16-20 month range and preoperational flexion was 26° (20°-30°. The quadriceps central tendon was stretched, without quadriceplasy, flexion being improved to 90° in 1 case and 100° to 120° in the remaining ones. Minimum follow-up lasted six months, average post-operational flexion being 109° (90°-120°. Discussion. The intermediate VMO has been used for applying drugs. There is evidence that this muscular portion has poor perfusion in children. The fibrosis's physiopathology is still not exactly known. Many children are given a poor diagnosis, this being confused with articular pathologies so that they wrongly receive other types of surgery.Antecedentes. La fibrosis del cuádriceps en niños es una patología reportada con frecuencia y asociada a la aplicación de antibióticos en el muslo. Este estudio presenta una serie de pacientes que tenían como antecedente común la aplicación de una dosis única de la vacuna pentavalente o de vitamina K y presentaron fibrosis del cuádriceps progresivo. Material y métodos. Se encontraron siete niños con retracción progresiva

  9. Coordinated collagen and muscle protein synthesis in human patella tendon and quadriceps muscle after exercise

    DEFF Research Database (Denmark)

    Miller, Benjamin F; Olesen, Jens L; Hansen, Mette

    2005-01-01

    We hypothesized that an acute bout of strenuous, non-damaging exercise would increase rates of protein synthesis of collagen in tendon and skeletal muscle but these would be less than those of muscle myofibrillar and sarcoplasmic proteins. Two groups (n = 8 and 6) of healthy young men were studied...... collagen (0.077% h(-1)), muscle collagen (0.054% h(-1)), myofibrillar protein (0.121% h(-1)), and sarcoplasmic protein (0.134% h(-1))). The rates decreased toward basal values by 72 h although rates of tendon collagen and myofibrillar protein synthesis remained elevated. There was no tissue damage...... of muscle visible on histological evaluation. Neither tissue microdialysate nor serum concentrations of IGF-I and IGF binding proteins (IGFBP-3 and IGFBP-4) or procollagen type I N-terminal propeptide changed from resting values. Thus, there is a rapid increase in collagen synthesis after strenuous exercise...

  10. Effect of eccentric exercise with reduced muscle glycogen on plasma interleukin-6 and neuromuscular responses of musculus quadriceps femoris.

    Science.gov (United States)

    Gavin, James P; Myers, Stephen D; Willems, Mark E T

    2016-07-01

    Eccentric exercise can result in muscle damage and interleukin-6 (IL-6) secretion. Glycogen availability is a potent stimulator of IL-6 secretion. We examined effects of eccentric exercise in a low-glycogen state on neuromuscular function and plasma IL-6 secretion. Twelve active men (23 ± 4 yr, 179 ± 5 cm, 77 ± 10 kg, means ± SD) completed two downhill treadmill runs (gradient, -12%, 5 × 8 min; speed, 12.1 ± 1.1 km/h) with normal (NG) and reduced muscle glycogen (RG) in randomized order and at least 6 wk apart. Muscle glycogen was reduced using an established cycling protocol until exhaustion and dietary manipulation the evening before the morning run. Physiological responses were measured up to 48 h after the downhill runs. During recovery, force deficits of musculus quadriceps femoris by maximal isometric contractions were similar. Changes in low-frequency fatigue were larger with RG. Voluntary activation and plasma IL-6 levels were similar in recovery between conditions. It is concluded that unaccustomed, damaging eccentric exercise with low muscle glycogen of the m. quadriceps femoris 1) exacerbated low-frequency fatigue but 2) had no additional effect on IL-6 secretion. Neuromuscular impairment after eccentric exercise with low muscle glycogen appears to have a greater peripheral component in early recovery.

  11. The effect of anterior cruciate ligament reconstruction on hamstring and quadriceps muscle function outcome ratios in male athletes

    Directory of Open Access Journals (Sweden)

    Kadija Marko

    2016-01-01

    Full Text Available Introduction. Maximal strength ratios such as the limb symmetry index (LSI and hamstring-to-quadriceps ratio (HQ may be considered the main outcome measures in the monitoring of recovery after anterior cruciate ligament (ACL reconstruction. Although explosive strength is much more important than maximal strength, it is generally disregarded in the follow-up of muscle function recovery. Objective. The purpose of this study was to compare ratios between maximal (Fmax and explosive strength (rate of force development - RFD in individuals with ACL reconstruction. Methods. Fifteen male athletes were enrolled and had maximum voluntary isometric quadriceps and hamstring contractions tested (4.0 ± 0.1 months post reconstruction. In addition to Fmax, RFD was estimated (RFDmax, as well as RFD at 50, 100, and 200 ms from onset of contraction and LSI and HQ ratios were calculated. Results. The involved leg demonstrated significant hamstring and quadriceps deficits compared to uninvolved leg (p < 0.01. Deficits were particularly significant in the involved quadriceps, causing higher HQ ratios (average 0.63, compared to the uninvolved leg (0.44. LSI was significantly lower for RFD variables (average 55% than for Fmax (66%. Conclusion. The assessment of RFD may be considered an objective recovery parameter for one’s readiness to return to sports and should be an integral part of standard follow-up protocol for athletes after ACL reconstruction. Moreover, the combination of indices derived from maximal and explosive strength may provide better insight in muscle strength balance, as well as a clear picture of functional implications. [Projekat Ministarstva nauke Republike Srbije, br. 175012 i br. 175037

  12. Strength Training to Contraction Failure Increases Voluntary Activation of the Quadriceps Muscle Shortly After Total Knee Arthroplasty

    DEFF Research Database (Denmark)

    Mikkelsen, Elin Karin; Jakobsen, Thomas Linding; Holsgaard-Larsen, Anders;

    2016-01-01

    OBJECTIVE: The objective of this study was to investigate voluntary activation of the quadriceps muscle during one set of knee extensions performed until contraction failure in patients shortly after total knee arthroplasty. DESIGN: This was a cross-sectional study of 24 patients with total knee...... arthroplasty. One set of knee extensions was performed until contraction failure, using a predetermined 10 repetition maximum loading. In the operated leg, electromyographic (EMG) activity of the lateral and medial vastus, semitendinosus, and biceps femoris muscles was recorded during the set. Muscle activity...... (%EMGmax) and median power frequency of the EMG power spectrum were calculated for each repetition decile (10%-100% contraction failure). RESULTS: Muscle activity increased significantly over contractions from a mean of 90.0 and 93.6 %EMGmax (lateral vastus and medial vastus, respectively) at 10...

  13. Muscle Activation Profiles and Co-Activation of Quadriceps and Hamstring Muscles around Knee Joint in Indian Primary Osteoarthritis Knee Patients.

    Science.gov (United States)

    Sharma, Sanjeev Kumar; Yadav, Shiv Lal; Singh, U; Wadhwa, Sanjay

    2017-05-01

    Osteoarthritis (OA) of knee is a common joint disease. It is associated with reduced knee joint stability due to impaired quadriceps strength, pain, and an altered joint structure. There is altered muscle activation in knee OA patients, which interferes with normal load distribution around the knee and facilitates disease progression. Our primary aim was to determine activation patterns of the muscles i.e., quadriceps and hamstrings in knee OA patients during walking. We also studied co-activation of muscles around knee joint in primary OA knee patients including directed medial and lateral co-contractions. This observational study was done at Department of Physical Medicine and Rehabilitation, All India Institute of Medical Sciences, New Delhi, India. Fourty-four patients with medial compartment primary knee OA were included in study after satisfying inclusion and exclusion criteria. All the patients were assessed for mean, peak and integrated Root Mean Square (RMS), EMG values, muscle activation patterns and co-activation of muscles around knee joint by surface Electromyography (EMG) analysis of Vastus Medialis Obliques (VMO), Vastus Lateralis (VL), Semitendinosus (SMT) and Biceps Femoris (BF) muscles during gait cycle. The EMG waveform for each muscle was amplitude normalized and time normalized to 100% of gait cycle and plotted on graph. Quantitative variables were assessed for normal distribution and accordingly mean±SD or median (range), as appropriate, was computed. For primary OA knee, mean age 61±5 years, mean weight 63.7±10.1 kg, mean height 153.9±7.2 cm, and mean Body Mass Index (BMI) 26.8±3.0 kg/m(2) was found. The muscle activity of hamstrings (SMT muscle and BF) was increased during midstance, late stance and early swing phase of gait cycle as compared to quadriceps (VMO and VL) muscle activity respectively, suggesting co-contraction of opposing muscles around knee joint. Patients with knee OA walk with increased hamstring muscle activity (during

  14. THE MID - TERM EFFECT OF KINESIO TAPING ON PEAK POWER OF QUADRICEPS AND HAMSTRING MUSCLES AFTER ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION

    Directory of Open Access Journals (Sweden)

    Amel Khabazan Mahdi

    2017-01-01

    Full Text Available Purpose: The aim of this study was to assess mid- term effect of Kinesio tape on peak power of quadriceps and hamstrings muscles after ACL reconstruction 24 hours after taping. Material: Thirty six men who had undergone ACL reconstruction and completed physiotherapy periods (6 months were assigned to no taping, placebo and taping groups. Peak power was tested before and 24 hours after taping by Isokinetic dynamometry. Data was analyzed by SPSS software 19. ANOVA and post hoc test (LSD were used for interpretive analysis. Results: The results showed that the effect of Kinesio tape on peak power of quadriceps muscles at velocities of 180°/s and 300°/s was significant. In the hamstring muscles, significant effects were obtained at velocities of 60°/s, 180°/s & 300°/s. Conclusion: Positive impacts of Kinesio tape on muscular peak power among athletes who had ACL reconstruction were observed. Regardless of psychological effect and reducing re - injury fear, Kinesio - tape causes to stabilize and increase effective range of motion of the knee, so it is recommended that in the explosive training, athletes who have ACL reconstruction should use tape to reduce the probability of re-injury and increase muscle power.

  15. The comparison of quadriceps muscle strength between sprint runner and normal un-trained individuals (Determined by Kin-Com

    Directory of Open Access Journals (Sweden)

    Talebian Moghaddam S "

    2002-08-01

    Full Text Available Introduction: It is suggested that quadriceps muscle has an important role in stability & mobility of Knee joint in athletics and normal individuals; therefore, the purpose of this study was evaluation of the strength in Power Athletics (PA and Normal Un-trained Individuals (NUI groups. Methods and Materials: 31 Females (20 NUI & 11 PA participated in this study. For measuring the strength, each individual performed 5 continuous concentric-eccentric maximal contraction at angular velocities of 90°/s, 135°/s. Twenty five percent of each individual (Maximum Voluntary Isometric Contraction MVIC was determined and used as Pre-load force. Results: Averages concentric & eccentric torques were greater in PA group in comparison with NUI group. The significant difference (P<0.02 existed between PA and NUI groups. Average concentric torques of quadriceps muscle decreased (with increasing of speed from 90°/s to 135°/s and average eccentric torques increased. Average eccentric torques were greater (P<0.01 in PA & NUI groups in comparison with average concentric torques. Conclusion: PA group strength was greater in comparison with NUI group. This is possibly due to the type of muscle fibers in this group have (greater type II fibers. Accordingly, it is critical to consider the role of eccentric exercise in PA group for preventing sport injury.

  16. Altered cell metabolism in tissues of the knee joint in a rabbit model of Botulinum toxin A-induced quadriceps muscle weakness.

    Science.gov (United States)

    Leumann, A; Longino, D; Fortuna, R; Leonard, T; Vaz, M A; Hart, D A; Herzog, W

    2012-12-01

    Quadriceps muscle weakness is frequently associated with knee injuries in sports. The influence of quadriceps weakness on knee joint homeostasis remains undefined. We hypothesized that quadriceps weakness will lead to tissue-specific alterations in the cell metabolism of tissues of the knee. Quadriceps weakness was induced with repetitive injections of Botulinum toxin A in six 1-year-old New Zealand White rabbits for 6 months. Five additional animals served as controls with injections of saline/dextrose. Muscle weakness was assessed by muscle wet mass, isometric knee extensor torque, and histological morphology analysis. Cell metabolism was assessed for patellar tendon, medial and lateral collateral ligament, and medial and lateral meniscus by measuring the total RNA levels and specific mRNA levels for collagen I, collagen III, MMP-1, MMP-3, MMP-13, TGF-β, biglycan, IL-1, and bFGF by reverse transcription and polymerase chain reaction. While the total RNA levels did not change, tissue-specific mRNA levels were lower for relevant anabolic and catabolic molecules, indicating potential changes in tissue mechanical set points. Quadriceps weakness may lead to adaptations in knee joint tissue cell metabolism by altering a subset of anabolic and catabolic mRNA levels corresponding to a new functional and metabolic set point for the knee that may contribute to the high injury rate of athletes with muscle weakness.

  17. Cross-sectional area measurements versus volumetric assessment of the quadriceps femoris muscle in patients with anterior cruciate ligament reconstructions

    Energy Technology Data Exchange (ETDEWEB)

    Marcon, Magda [University Hospital Zurich, Department of Radiology, Zurich (Switzerland); University Hospital Udine, Department of Radiology, Udine (Italy); Ciritsis, Bernhard; Laux, Christoph [University Hospital Zurich, Department of Traumatology, Zurich (Switzerland); Nanz, Daniel; Nguyen-Kim, Thi Dan Linh; Fischer, Michael A.; Andreisek, Gustav; Ulbrich, Erika J. [University Hospital Zurich, Department of Radiology, Zurich (Switzerland)

    2014-10-31

    Our aim was to validate the use of cross-sectional area (CSA) measurements at multiple quadriceps muscle levels for estimating the total muscle volume (TMV), and to define the best correlating measurement level. Prospective institutional review board (IRB)-approved study with written informed patient consent. Thighs of thirty-four consecutive patients with ACL-reconstructions (men, 22; women, 12) were imaged at 1.5-T using three-dimensional (3D) spoiled dual gradient-echo sequences. CSA was measured at three levels: 15, 20, and 25 cm above the knee joint line. TMV was determined using dedicated volumetry software with semiautomatic segmentation. Pearson's correlation and regression analysis (including standard error of the estimate, SEE) was used to compare CSA and TMV. The mean ± standard deviation (SD) for the CSA was 60.6 ± 12.8 cm{sup 2} (range, 35.6-93.4 cm{sup 2}), 71.1 ± 15.1 cm{sup 2} (range, 42.5-108.9 cm{sup 2}) and 74.2 ± 17.1 cm{sup 2} (range, 40.9-115.9 cm{sup 2}) for CSA-15, CSA-20 and CSA-25, respectively. The mean ± SD quadriceps' TMV was 1949 ± 533.7 cm{sup 3} (range, 964.0-3283.0 cm{sup 3}). Pearson correlation coefficient was r = 0.835 (p < 0.01), r = 0.906 (p < 0.01), and r = 0.956 (p < 0.01) for CSA-15, CSA-20 and CSA-25, respectively. Corresponding SEE, expressed as percentage of the TMV, were 15.2 %, 11.6 % and 8.1 %, respectively. The best correlation coefficient between quadriceps CSA and TMV was found for CSA-25, but its clinical application to estimate the TMV is limited by a relatively large SEE. (orig.)

  18. Reproducibility of contractile properties of the human paralysed and non-paralysed quadriceps muscle.

    NARCIS (Netherlands)

    Gerrits, H.L.; Hopman, M.T.E.; Sargeant, A.J.; Haan, A. de

    2001-01-01

    This study assessed the reproducibility of electrically evoked, isometric quadriceps contractile properties in eight people with spinal cord injury (SCI) and eight able-bodied (AB) individuals. Over all, the pooled coefficients of variation (CVps) in the SCI group were significantly lower (ranging

  19. Synergists activation pattern of the quadriceps muscle differs when performing sustained isometric contractions with different EMG biofeedback.

    Science.gov (United States)

    Place, Nicolas; Matkowski, Boris; Martin, Alain; Lepers, Romuald

    2006-10-01

    The aims of the present study were to examine (1) endurance time and (2) activation pattern of vastus lateralis (VL), vastus medialis (VM) and rectus femoris (RF) muscles during fatiguing isometric knee extensions performed with different EMG biofeedbacks. Thirteen men (27 +/- 5 year) volunteered to participate in three experimental sessions. Each session involved a submaximal isometric contraction held until failure at an EMG level corresponding to 40% maximal voluntary contraction torque (MVC), with visual EMG biofeedback provided for either (1) RF muscle (RF task), (2) VL and VM muscles (Vasti task) or (3) the sum of the VL, VM and RF muscles (Quadriceps task). EMG activity of VL, VM and RF muscles was recorded during each of the three tasks and further analyzed. Time to task failures and MVC loss (P 0.05) between the three sessions (182 s and approximately 28%, respectively) (P > 0.05). Moreover, the magnitude of central and peripheral fatigue was not different at failure of the three tasks. Activation pattern was similar for knee extensors at the beginning of each task (P > 0.05). However, RF EMG activity decreased (P pattern for the bi-articular RF muscle compared to the mono-articular vasti muscles during fatigue.

  20. EFFECT OF RUSSIAN CURRENT ON QUADRICEPS MUSCLE STRENGTH IN SUBJECTS WITH PRIMARY OSTEOARTHRITIS OF KNEE: A RANDOMIZED CONTROL TRIAL

    Directory of Open Access Journals (Sweden)

    Anand B Heggannavar

    2014-06-01

    Full Text Available Relevance: OA knee is one of the most common conditions leading functional disabilities seen worldwide. There are different methods to manage osteoarthritis, conservatively, and/or surgically. Physiotherapy treatment, as a part of conservative management, involves reduction of pain, improvement of muscle strength and improvement of functional ability by various approaches like exercise therapy, electrotherapy and manual therapy techniques. Quadriceps muscle weakness is one of the main features seen in OA knee. Russian current stimulation has been successfully used to increase muscle strength in healthy athletes but its effect on quadriceps muscle strength in OA knee has not been studied. Hence the present study was undertaken to know the effect of Russian current stimulation on quadriceps muscle strength in patients with primary OA knee. Participants: 30 subjects (mean age 50.25±6.35 years diagnosed with primary OA knee were recruited from Out-Patient Department of Physiotherapy of KLES Dr. Prabhakar Kore Hospital and Medical Research Centre, Belgaum. Method: Subjects were randomly allocated into 2 groups namely Group A (n=15 who received Short Wave Diathermy (SWD and exercises and Group B (n=15 who received SWD, exercises and Russian current stimulation for 10 days. The outcome measures were Visual Analog Scale (VAS for pain, muscle strength by using Handheld dynamometer, and WOMAC osteoarthritis index for functional disability. Analysis: Within group and between group analysis after intervention was done to assess changes using paired t-test and unpaired t - tests. Result: The VAS scores for group A reduced from 6.8±1.49 (baseline to1.4±0.91 (post-intervention and for group B from 6.3±1.29 (baseline to 1±1.14 (post-intervention. The WOMAC score of group A decreased from 59.7±11.56 (baseline to 24.1±6.01 (post-intervention and of group B decreased from 50.4±22.30 (baseline to 12.5±7.54 (post-intervention. The muscle strength of group A

  1. Repeatability of maximal voluntary force and of surface EMG variables during voluntary isometric contraction of quadriceps muscles in healthy subjects.

    Science.gov (United States)

    Rainoldi, A; Bullock-Saxton, J E; Cavarretta, F; Hogan, N

    2001-12-01

    The repeatability of initial values and rate of change of EMG signal mean spectral frequency (MNF), average rectified values (ARV), muscle fiber conduction velocity (CV) and maximal voluntary contraction (MVC) was investigated in the vastus medialis obliquus (VMO) and vastus lateralis (VL) muscles of both legs of nine healthy male subjects during voluntary, isometric contractions sustained for 50 s at 50% MVC. The values of MVC were recorded for both legs three times on each day and for three subsequent days, while the EMG signals have been recorded twice a day for three subsequent days. The degree of repeatability was investigated using the Fisher test based upon the ANalysis Of VAriance (ANOVA), the Standard Error of the Mean (SEM) and the Intraclass Correlation Coefficient (ICC). Data collected showed a high level of repeatability of MVC measurement (normalized SEM from 1.1% to 6.4% of the mean). MNF and ARV initial values also showed a high level of repeatability (ICC>70% for all muscles and legs except right VMO). At 50% MVC level no relevant pattern of fatigue was observed for the VMO and VL muscles, suggesting that other portions of the quadriceps might have contributed to the generated effort. These observations seem to suggest that in the investigation of muscles belonging to a multi-muscular group at submaximal level, the more selective electrically elicited contractions should be preferred to voluntary contractions.

  2. Morphological and qualitative characteristics of the quadriceps muscle of community-dwelling older adults based on ultrasound imaging: classification using latent class analysis.

    Science.gov (United States)

    Kawai, Hisashi; Kera, Takeshi; Hirayama, Ryo; Hirano, Hirohiko; Fujiwara, Yoshinori; Ihara, Kazushige; Kojima, Motonaga; Obuchi, Shuichi

    2017-06-02

    Muscle thickness and echo intensity measured using ultrasound imaging represent both increased muscle volume and connective tissue accumulation. In combination, these ultrasound measurements can be utilized for assessing sarcopenia in community-dwelling older adults. This study aimed to determine whether morphological and qualitative characteristics classified by quadriceps muscle thickness and echo intensity measured using ultrasound are associated with muscle strength, physical function, and sarcopenia in community-dwelling older adults. Quadriceps muscle thickness and echo intensity were measured using ultrasound imaging in 1239 community-dwelling older adults. Latent class analyses were conducted to classify participants based on similarity in the subcutaneous fat thickness (FT), quadriceps muscle thickness (MT), subcutaneous fat echo intensity (FEI), and muscle echo intensity (MEI), which were assessed using ultrasound imaging. Morphological and qualitative characteristics were classified into four types as follows: (A) normal, (B) sarcopenic obesity, (C) obesity, and (D) sarcopenia type. Knee extension strength was significantly greater in A than in B and D. FT and percent body fat were greater in C than in the other types. The correlation between the ultrasound measures and knee extension strength differed among the classification types. The classification types were significantly associated with sarcopenia prevalence. Classification of the morphological and qualitative characteristics obtained from ultrasound imaging may be useful for assessing sarcopenia in community-dwelling older adults.

  3. Effect of L-Glutamine Supplementation on Electromyographic Activity of the Quadriceps Muscle Injured By Eccentric Exercise

    Directory of Open Access Journals (Sweden)

    Farhad Rahmani Nia

    2013-06-01

    Full Text Available   Objective(s: The purpose of the present study was to examine the effects of L-glutamine on electromyographic (EMG activity of the quadriceps muscle injured by eccentric exercise (EE.   Materials and Methods: Seventeen healthy men (age: 22.35±2.27 yr; body mass: 69.91±9.78 kg; height: 177.08±4.32 cm were randomly and double-blind study with subjects assigned to either an L-glutamine supplementation (n=9 or placebo (n=8 group. The subjects in two groups were asked to take three times during a week for 4 weeks. Each subject was screened for dietary habits before inclusion into the study. Participants performed 6 set to exhaustion eccentric leg extensions at 75% of 1RM and rest intervals were 3 min among sets. Pain Assessment Scale (PAS, EMG activity and range of motion (ROM measurements were taken before exercise protocol and 24 and 48 hr afterwards. Results: There was no statistically significant difference between groups in perceived muscle soreness (SOR, ROM and EMG activity (P < 0.05. Conclusion: The results indicate that L-glutamine supplementation has no significant effect on muscle injury markers in between groups, although glutamine supplementation attenuated delayed onset muscle soreness (DOMS effects in sup group.

  4. [Innervation disturbances of the quadriceps muscle in chondropathia patellae. A critical appraisal of the current concept of chondropathia].

    Science.gov (United States)

    Weh, L; Eickhoff, W

    1983-01-01

    In a group of patients with typical histories of chondropathy, but in whom no other criteria of selection were applied, evidence of neurogenic damage in the quadriceps muscle was found. Innervational damage was also found regularly in the corresponding segments of the paravertebral musculature. Only in three cases, in which horn cell damage was suspected, were there no changes in the paravertebral musculature. There were abnormal structural or functional findings in the lumbar spine in all the patients. A disequilibrium between the median and lateral vastus groups, attributable to innervation, was postulated and subsequently confirmed by electromyography. The nature of chondropathia patellae as an insertion tendopathy is discussed, taking the lack of concomitance of chondropathy and chondromalacia into consideration as well as the findings in the group of patients examined. Phenomena associated with chondropathy which have hitherto incongruous may be explained on the basis of an asymmetrical innervation disturbance.

  5. RAPID HAMSTRINGS/QUADRICEPS STRENGTH CAPACITY IN PROFESSIONAL SOCCER PLAYERS WITH DIFFERENT CONVENTIONAL ISOKINETIC MUSCLE STRENGTH RATIOS

    Directory of Open Access Journals (Sweden)

    Camila C. Greco

    2012-09-01

    Full Text Available Muscle strength imbalance can be an important factor in hamstrings muscle strain. A hamstrings/quadriceps (H/Q strength ratio based on concentric peak torque values (Hcon:Qcon has traditionally been used to describe the potential for knee-joint destabilization. Because certain standard actions in soccer are explosive, the analysis of the H/Q strength ratio based on the rate of torque development (Hrtd:Qrtd might also be useful in the evaluation of joint stability. The objective of this study was to compare the Hrtd:Qrtd between professional soccer players with heterogeneous values of Hcon:Qcon. Thirty-nine professional soccer players took part in the following procedures on different days: 1 Familiarization session with the isokinetic dynamometer, and 2 Two maximal isometric actions and five maximal concentric actions at 60°·s-1 for hamstrings (H and quadriceps (Q. Participants were ranked according to their Hcon:Qcon ratio. The median third was excluded to form a high torque group (HTG, and a low torque group (LTG. Peak isometric (H and concentric (H and Q torques and rate of torque development (H were significantly greater in the HTG group. Similarly, Hcon:Qcon (0.68 ± 0.02 vs. 0.52 ± 0.03 and Hrtd:Qrtd (0.54 ± 0.12 vs. 0.43 ± 0.16 were significantly greater in the HTG group than in the LTG group. There was no significant correlation between Hcon:Qcon and Hrtd:Qrtd. It can be concluded that Hcon:Qcon and Hrtd:Qrtd are determined, but not fully defined, by shared putative physiological mechanisms. Thus, the physiologic and clinical significance of Hcon:Qcon and Hrtd:Qrtd to an athlete's individual evaluation might be different

  6. Validity and reliability of isometric, isokinetic and isoinertial modalities for the assessment of quadriceps muscle strength in patients with total knee arthroplasty.

    Science.gov (United States)

    Lienhard, K; Lauermann, S P; Schneider, D; Item-Glatthorn, J F; Casartelli, N C; Maffiuletti, N A

    2013-12-01

    Reliability of isometric, isokinetic and isoinertial modalities for quadriceps strength evaluation, and the relation between quadriceps strength and physical function was investigated in 29 total knee arthroplasty (TKA) patients, with an average age of 63 years. Isometric maximal voluntary contraction torque, isokinetic peak torque, and isoinertial one-repetition maximum load of the involved and uninvolved quadriceps were evaluated as well as objective (walking parameters) and subjective physical function (WOMAC). Reliability was good and comparable for the isometric, isokinetic, and isoinertial strength outcomes on both sides (intraclass correlation coefficient range: 0.947-0.966; standard error of measurement range: 5.1-9.3%). Involved quadriceps strength was significantly correlated to walking speed (r range: 0.641-0.710), step length (r range: 0.685-0.820) and WOMAC function (r range: 0.575-0.663), independent from the modality (P torque (P > 0.05). In conclusion, isometric, isokinetic, and isoinertial modalities ensure valid and reliable assessment of quadriceps muscle strength in TKA patients.

  7. Range of motion and leg rotation affect EMG activation levels of the superficial quadriceps muscles during leg extension.

    Science.gov (United States)

    Signorile, Joseph F; Lew, Karen; Stoutenberg, Mark; Pluchino, Alessandra; Lewis, John E; Gao, Jinrun

    2014-06-30

    The leg extension (LE) is commonly used to strengthen the quadriceps muscles during training and rehabilitation. This study examined the effects of limb position (POS) and range of motion (ROM) on quadriceps electromyography (EMG) during 8 repetitions (REP) of LE. Twenty-four participants performed eight LE REP at their 8-repetition maximum with lower limbs medially rotated (TI), laterally rotated (TO), and neutral (NEU). Each REP EMG was averaged over the first, middle, and final 0.524 rad ROM. For vastus medialis oblique (VMO), a REP x ROM interaction was detected (p<0.02). The middle 0.524 rad produced significantly higher EMG than the initial 0.524 rad for REP 6-8 and the final 0.524 rad produced higher EMG than the initial 0.524 rad for REP 1, 2, 3, 4, 6, 8 (p<0.05). For rectus femoris (RF), EMG activity increased across REP with TO generating the greatest activity (p<0.001). For vastus lateralis (VL), EMG increased across REP (p<0.001) with NEU and TO EMG increasing linearly throughout ROM, and TI activity greatest during the middle 0.524 rad. We conclude that to target the VMO the optimal ROM is the final 1.047 rad regardless of POS, while maximum EMG for the RF is generated using TO regardless of ROM. In contrast, the VL is maximally activated using TI over the first 1.047 rad ROM or in NEU over the final 0.524 rad ROM.

  8. Range of motion and leg rotation affect electromyography activation levels of the superficial quadriceps muscles during leg extension.

    Science.gov (United States)

    Signorile, Joseph F; Lew, Karen M; Stoutenberg, Mark; Pluchino, Alessandra; Lewis, John E; Gao, Jinrun

    2014-09-01

    Leg extension (LE) is commonly used to strengthen the quadriceps muscles during training and rehabilitation. This study examined the effects of limb position (POS) and range of motion (ROM) on quadriceps electromyography (EMG) during 8 repetitions (REP) of LE. Twenty-four participants performed 8 LE REP at their 8 repetition maximum with lower limbs medially rotated (TI), laterally rotated (TO), and neutral (NEU). Each REP EMG was averaged over the first, middle, and final 0.524 rad ROM. For vastus medialis oblique (VMO), a REP × ROM interaction was detected (p < 0.02). The middle 0.524 rad produced significantly higher EMG than the initial 0.524 rad for REP 6-8 and the final 0.524 rad produced higher EMG than the initial 0.524 rad for REP 1, 2, 3, 4, 6, and 8 (p ≤ 0.05). For rectus femoris (RF), EMG activity increased across REP with TO generating the greatest activity (p < 0.001). For vastus lateralis (VL), EMG increased across REP (p < 0.001) with NEU and TO EMG increasing linearly throughout ROM and TI activity greatest during the middle 0.524 rad. We conclude that to target the VMO, the optimal ROM is the final 1.047 rad regardless of POS, while maximum EMG for the RF is generated using TO regardless of ROM. In contrast, the VL is maximally activated using TI over the first 1.047 rad ROM or in NEU over the final 0.524 rad ROM.

  9. A stochastic model of knee angle in response to electrical stimulation of the quadriceps and hamstrings muscles.

    Science.gov (United States)

    Lynch, Cheryl L; Popovic, Milos R

    2011-12-01

    A novel stochastic model of knee angle in response to stimulation of the quadriceps and hamstrings muscle groups is presented. This model includes uncertainty due to fatigue and day-to-day changes in the stimulated muscles. The model consists of a normally distributed random variable whose mean and standard deviation vary with time and is characterized using data from a complete spinal cord injuries subject. The experimental data show a significant difference between the left and right legs under certain conditions, and suggest that fatigue-related and day-to-day variation may also be important. The purpose of this model is to generate more realistic electrically stimulated knee movements. This stochastic modeling technique could be incorporated into a comprehensive model of a joint actuated with electrical stimulation, and has great potential as a tool for analyzing closed-loop performance of electrically stimulated systems. © 2011, Copyright the Authors. Artificial Organs © 2011, International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.

  10. Effect of endurance versus resistance training on quadriceps muscle dysfunction in COPD

    DEFF Research Database (Denmark)

    Iepsen, Ulrik Winning; Munch, Gregers Druedal Wibe; Rugbjerg, Mette

    2016-01-01

    INTRODUCTION: Exercise is an important countermeasure to limb muscle dysfunction in COPD. The two major training modalities in COPD rehabilitation, endurance training (ET) and resistance training (RT), may both be efficient in improving muscle strength, exercise capacity, and health-related quali...

  11. Exposure to microgravity for 30 days onboard Bion M1 caused muscle atrophy and decreased regeneration in the mouse femoral Quadriceps

    Science.gov (United States)

    Grigoryan, Eleonora; Radugina, Elena A.; Almeida, Eduardo; Blaber, Elizabeth; Poplinskaya, Valentina; Markitantova, Yulia

    Mechanical unloading of muscle during spaceflight in microgravity is known to cause muscular atrophy, changes in muscle fiber type composition, gene expression, and reductions in regenerative muscle growth. Although limited data exists for long-term effects of microgravity in human muscle, these processes have mostly been studied in rodents for short periods of time, up to two weeks of spaceflight. Here we report on how 30-day, long-term, mechanical unloading in microgravity affects mouse muscle of the femoral Quadriceps group. To conduct these studies we used muscle tissue from 6 mice from the NASA Biospecimen Sharing Program conducted in collaboration with the Institute for Biomedical Problems of the Russian Academy of Sciences, during the Russian Bion M1 biosatellite mission in 2013. Muscle morphology observed in histological sections shows signs of extensive atrophy and regenerative hypoplasia. Specifically, we observed a two-fold decrease in the number of myonuclei and low density of myofibrils, their separation and fragmentation. Despite obvious atrophy, muscle regeneration nevertheless appears to have continued after 30 days in microgravity as evidenced by thin and short newly formed muscle fibers. Many of them however showed evidence of apoptosis and degradation of synthesized fibrils, suggesting long-term unloading in microgravity affects late stages of myofiber differentiation. Ground asynchronous and vivarium control animals showed normal, well-developed tissue structure with sufficient blood and nerve supply and evidence of regenerative formation of new muscle fibers free of apoptotic nuclei. Myofiber nuclei stress responses in spaceflight animals was detected by positive nuclear immunolocalization of c-jun and c-myc proteins. Regenerative activity of satellite cells in muscle was localized with pax-7, MyoD and MCad immunostaining, and did not appear altered in microgravity. In summary, long-term spaceflight in microgravity causes significant atrophy

  12. {sup 99m}Tc-sestamibi muscle scintigraphy to assess the response to neuromuscular electrical stimulation of normal quadriceps femoris muscle

    Energy Technology Data Exchange (ETDEWEB)

    Pekindil, Y.; Sarikaya, A.; Birtane, M.; Pekindil, G.; Salan, A. [Trakya Univ., Edirne (Turkey). Hospital

    2001-08-01

    Neuromuscular electrical stimulation (NMES) is widely used for improving muscle strength by simultaneous contraction in the prevention of muscle atrophy. Although there exist many clinical methods for evaluating the therapeutic response of muscles, {sup 99m}Tc-sestamibi which is a skeletal muscle perfusion and metabolism agent has not previously been used for this purpose. The aim of our work was to ascertain whether {sup 99m}Tc-sestamibi muscle scintigraphy is useful in the monitoring of therapeutic response to NMES in healthy women. The study included 16 women aged between 21 and 45, with a mean age of 32.7{+-}6.4. Both quadriceps femoris muscles (QFM) of each patient were studied. After randomization to remove the effect of the dominant side, one QFM of each patient was subjected to the NMES procedure for a period of 20 days. NMES was performed with an alternating biphasic rectangular current, from a computed electrical stimulator daily for 23 minutes. After measurement of skinfold thickness over the thigh, pre- and post-NMES girth measurements were assessed in centimeters. Sixty minutes after injections of 555 MBq {sup 99m}Tc-sestamibi, static images of the thigh were obtained for 5 minutes. The thigh-to-knee uptake ratio was calculated by semiquantitative analysis and normalized to body surface area (NUR=normalized uptake ratio). The difference between the pre and post NMES NUR values was significant (1.76{+-}0.31 versus 2.25{+-}0.38, p=0.0000). The percentage (%) increase in NUR values also well correlated with the % increase in thigh girth measurements (r=0.89, p=0.0000). These results indicated that {sup 99m}Tc-sestamibi muscle scintigraphy as a new tool may be useful in evaluating therapeutic response to NMES. (author)

  13. RAPID KNEE-EXTENSIONS TO INCREASE QUADRICEPS MUSCLE ACTIVITY IN PATIENTS WITH TOTAL KNEE ARTHROPLASTY: A RANDOMIZED CROSS-OVER STUDY

    Science.gov (United States)

    Wilquin, Lousia; Jakobsen, Thomas Linding; Holsgaard-Larsen, Anders; Bandholm, Thomas

    2017-01-01

    Background Inhibition of the quadriceps muscle and reduced knee-extension strength is common shortly following total knee arthroplasty (weeks to months), due to reduced voluntary activation of the quadriceps muscle. In healthy subjects, strength training with heavy loads is known to increase agonist muscle activity, especially if the exercise is conducted using rapid muscle contractions. Purpose The purpose of this study was to examine if patients with total knee arthroplasty could perform rapid knee-extensions using a 10 RM load four to eight weeks after surgery, and the degree to which rapid knee-extensions were associated with greater voluntary quadriceps muscle activity during an experimental strength training session, compared to that elicited using slow knee-extensions. Study Design A randomized cross-over study. Methods Twenty-four patients (age 66.5) 4-8 weeks post total knee arthroplasty randomly performed one set of five rapid, and one set of five slow knee-extensions with the operated leg, using a load of their 10 repetition maximum, while surface electromyography recordings were obtained from the vastus medialis and lateralis of the quadriceps muscle. Results Data from 23 of the 24 included patients were analyzed. Muscle activity was significantly higher during rapid knee-extensions (120.2% [10th-90th percentile: 98.3-149.1]) compared to slow knee-extensions (106.0% [88.8-140.8]) for the vastus lateralis (pknee-extensions were performed at a median angular velocity of 19.7 degrees/sec (13.7-24.4) and 51.4 degrees/sec (28.9-63.1), respectively Conclusion Four to eight weeks after their total knee arthroplasty, the patients in the present study were able to conduct rapid knee-extensions according to the experimental protocol with an approximately doubled angular velocity compared to slow knee-extensions. This was associated with increased muscle activity in the vastus lateralis when compared to slow knee-extensions, but not in the vastus medialis. Whether

  14. Investigation of the quadriceps muscle function in healthy elderly%老年健康人股四头肌功能的调查和分析

    Institute of Scientific and Technical Information of China (English)

    巨春蓉; 陈荣昌

    2013-01-01

    目的 检测健康老年人股四头肌的功能,分析其相关因素,建立老年人股四头肌功能的正常值. 方法 60例老年人纳入研究,股四头肌功能测试包括三项指标:磁刺激股神经诱发的最大肌颤搐张力(TwQmax)、最大主动收缩力(QMVC)、耐力时间.对受试者的日常运动(PA)进行量化分析并评分,对身高、体质量、肌肉体积等进行人体学测量. 结果 股四头肌功能3项检测结果在男女组均呈正态分布.TwQmax、QMVC和耐力时间的均值及正常范围在男性组分别为[13.86(10.53~17.65)]kg、[42.06 (34.45~49.67)]kg、[81.08(58.52~103.66)]s,在女性组分别为[7.41(6.02~9.52)]kg、[29.40 (24.66~33.82)]kg、[83.44(60.81~106.67)]s.回归分析结果显示,股四头肌功能与受试者的性别、PA评分、身高、体质量及肌肉体积等因素相关. 结论 老年健康者股四头肌功能在人群中呈正态分布,其与受试者的性别、体质量等多因素有关,而肌肉运动情况是影响肌肉功能的最主要因素.%Objective Backgrounds and Objectives Skeletal muscle dysfunction is an important systemic manifestation of several diseases such as chronic obstructive pulmonary disease and chronic heart failure.Quadriceps function assessment was used in majority of the studies for assessment of peripheral skeletal muscle function as it is readily accessible and is a primary locomotor muscle.Appropriate evaluation of the prevalence and severity of quadriceps dysfunction relies on the proper control data from the age-matched normal subject.So,the present study was aimed to measure the quadriceps function in healthy elderly,to investigate the multiple factors related to quadriceps functions,and to establish the normal ranges for quadriceps functional performance in healthy elderly.Methods Sixty healthy volunteers were recruited for the study.Quadriceps function was assessed by measurement of the following 3 items:maximum of twitch tension (Tw

  15. The twitch interpolation technique for the estimation of true quadriceps muscle strength.

    Science.gov (United States)

    Nørregaard, J; Lykkegaard, J J; Bülow, P M; Danneskiold-Samsøe, B

    1997-09-01

    The aim of this study was to examine the reliability of the twitch interpolation technique when used to estimate the true isometric knee extensor muscle strength. This included an examination of whether submaximal activation causes any bias in the estimation of the true muscle strength and an examination of the precision of the method. Twenty healthy subjects completed three contraction series, in which the subjects were told to perform as if their voluntary strength was 60%, 80% or 100% of that determined by a maximal voluntary contraction (MVC). Electrical muscle stimulations were given at each of five different contraction levels in each series. At torque levels above 25% of MVC the relationship between torque and twitch size could be approximated to be linear. The true muscle strength (TMS) could therefore be estimated using linear regression of the twitch-torque relationship to the torque point of no twitch in each of the three series, termed TMS60, TMS80 and TMS100. The TMS80 was slightly lower (P estimated central activation of below 40-50% were excluded. The only moderate precision and the slightly lower estimations in subjects applying submaximal does, however, limit its usefulness.

  16. Aerobic metabolism of human quadriceps muscle: in vivo data parallel measurements on isolated mitochondria

    DEFF Research Database (Denmark)

    Rasmussen, Ulla Fugmann; Rasmussen, Hans N.; Krustrup, Peter;

    2001-01-01

    by the rate of ATP synthesis, could account for, at most, 60% of the O2 max. This might be due to systematic errors or to loose coupling of the mitochondrial respiration under intense exercise. skeletal muscles; maximal oxygen uptake; work rate; respiration; adenosine triphosphate synthesis...

  17. Dynamic {sup 31}P-MR-spectroscopy of the quadriceps muscle. Influence of sex and age on spectroscopic results; Die dynamische 31-Phosphor-Magnetresonanz-Spektroskopie des M. quadriceps. Einfluss von Geschlecht und Alter auf spektroskopische Parameter

    Energy Technology Data Exchange (ETDEWEB)

    Schunk, K.; Romaneehsen, B.; Kessler, S.; Schadmand-Fischer, S.; Thelen, M. [Mainz Univ. (Germany). Klinik und Poliklinik fuer Radiologie

    1999-05-01

    Purpose: {sup 31}P-MRS is used to assess the influence of sex and age on quadriceps muscle metabolism before and after exercise. Materials and Methods: 32 healthy volunteers (15 women, 17 men; mean age: 38{+-}17 yrs.) were examined by dynamic phosphorus-31 ({sup 31}P) magnetic resonance spectroscopy (MRS). In the magnet, the quadriceps muscle was stressed by an isometric and an isotonic form of exercise until exhaustion, respectively. Results: Resting conditions: With increasing subjects` age, the ratio {beta}-adenosine triphosphate/total phosphate decreased (r=-0.37; p=0.02). With increasing subjects` age, the ratios inorganic phosphate/phosphocreatine (r=0.79; p=5x10{sup -8}), phosphomonoester/{beta}-adenosine triphosphate (r=0.74; p=10{sup -6}) and phosphodiester/{beta}-adenosine triphosphate (r=0.62; p=10{sup -4}) increased. The pH was the only one of the evaluated spectroscopic parameters which showed a sex-dependence: Female subjects had a significantly lower pH (7.03{+-}0.02) than male subjects (7.05{+-}0.03; p=0,01). Exercise: With increasing age, the maxima of inorganic phosphate/phosphocreatine were less extreme during both of the exercises (r=-0.42; p=0.0005). Likewise, the exercise-induced acidosis was less severe with increasing age (r=0.53; p=6x10{sup -6}). After the end of the exercise, the times of half recovery of inorganic phosphate/phosphocreatine and the pH correlated neither with the subjects` age nor with sex or cross-sectional area of the quadriceps muscle. Conclusion: Sex and age of volunteers affect spectroscopic results. This influence has to be considered in the interpretation of spectroscopic studies. (orig.) [Deutsch] Ziel: Die Ueberpruefung des Einflusses von Geschlecht und Alter gesunder Probanden auf phosphorspektroskopische Ergebnisse. Material und Methodik: 32 gesunde Probanden (15 Frauen, 17 Maenner) mit einem Durchschnittsalter von 38{+-}17 Jahren wurden mit der dynamischen 31-Phosphor-Magnetresonanz-Spektroskopie (MRS

  18. Chronic eccentric cycling improves quadriceps muscle structure and maximum cycling power.

    Science.gov (United States)

    Leong, C H; McDermott, W J; Elmer, S J; Martin, J C

    2014-06-01

    An interesting finding from eccentric exercise training interventions is the presence of muscle hypertrophy without changes in maximum concentric strength and/or power. The lack of improvements in concentric strength and/or power could be due to long lasting suppressive effects on muscle force production following eccentric training. Thus, improvements in concentric strength and/or power might not be detected until muscle tissue has recovered (e. g., several weeks post-training). We evaluated alterations in muscular structure (rectus-femoris, RF, and vastus lateralis, VL, thickness and pennation angles) and maximum concentric cycling power (Pmax) 1-week following 8-weeks of eccentric cycling training (2×/week; 5-10.5 min; 20-55% of Pmax). Pmax was assessed again at 8-weeks post-training. At 1 week post-training, RF and VL thickness increased by 24±4% and 13±2%, respectively, and RF and VL pennation angles increased by 31±4% and 13±1%, respectively (all Peccentric cycling can be a time-effective intervention for improving muscular structure and function in the lower body of healthy individuals. The larger Pmax increase detected at 8-weeks post-training implies that sufficient recovery might be necessary to fully detect changes in muscular power after eccentric cycling training.

  19. Work capacity and metabolic and morphologic characteristics of the human quadriceps muscle in response to unloading

    Science.gov (United States)

    Berg, H. E.; Dudley, G. A.; Hather, B.; Tesch, P. A.

    1993-01-01

    The response of skeletal muscle to unweighting was studied in six healthy males who were subjected to four weeks of lowerlimb suspension. They performed three bouts of 30 consecutive maximal concentric knee extensions, before unloading and the day after (POST 1), 4 days after (POST 2) and 7 weeks after (REC) resumed weight-bearing. Peak torque of each contraction was recorded and work was calculated as the mean of the average peak torque for the three bouts and fatigability was measured as the decline in average peak torque over bouts. Needle biopsies were obtained from m. vastus lateralis of each limb before and at POST 1. Muscle fibre type composition and area, capillarity and the enzyme activities of citrate synthase (CS) and phosphofructokinase (PFK) were subsequently analysed. Mean average peak torque for the three bouts at POST1, POST2 and REC was reduced (P 0.05) in response to unloading. The activity of CS, but not PFK, decreased (P < 0.05) after unloading. The weight-bearing limb showed no changes in the variables measured. The results of this study suggest that this human lowerlimb suspension model produces substantial impairments of work and oxidative capacity of skeletal muscle. The performance decrements are most likely induced by lack of weight-bearing.

  20. Eccentric exercise and delayed onset muscle soreness of the quadriceps induce adjustments in agonist-antagonist activity, which are dependent on the motor task.

    Science.gov (United States)

    Vila-Chã, C; Hassanlouei, H; Farina, D; Falla, D

    2012-02-01

    This study investigates the effects of eccentric exercise and delayed onset muscle soreness (DOMS) of the quadriceps on agonist-antagonist activity during a range of motor tasks. Ten healthy volunteers (age, mean ± SD, 24.9 ± 3.2 years) performed maximum voluntary contractions (MVC) and explosive isometric contractions of the knee extensors followed by isometric contractions at 2.5, 5, 10, 15, 20, and 30% MVC at baseline, immediately after and 24 h after eccentric exercise of the quadriceps. During each task, force of the knee extensors and surface EMG of the vasti and hamstrings muscles were recorded concurrently. Rate of force development (RFD) was computed from the explosive isometric contraction, and the coefficient of variation of the force (CoV) signal was estimated from the submaximal contractions. Twenty-four hours after exercise, the subjects rated their perceived pain intensity as 4.1 ± 1.2 (score out of 10). The maximum RFD and MVC of the knee extensors was reduced immediately post- and 24 h after eccentric exercise compared to baseline (average across both time points: 19.1 ± 17.1% and 11.9 ± 9.8% lower, respectively, P eccentric exercise (up to 66% higher than baseline, P exercise during the presence of DOMS (P exercise and was accompanied by increased antagonist EMG for the explosive contraction only. On the contrary, reduced force steadiness was accompanied by a general increase in EMG amplitude of the vasti muscles and was accompanied by increased antagonist activity, but only at higher force levels (>15% MVC). This study shows that eccentric exercise and subsequent DOMS of the quadriceps reduce the maximal force, rate of force development and force steadiness of the knee extensors, and is accompanied by different adjustments of agonist and antagonist muscle activities.

  1. EFFECTIVENESS OF CONCENTRIC AND ECCENTRIC RESISTANCE TRAINING OF QUADRICEPS AND HAMSTRINGS ON MUSCLE STRENGTH, ROM, AND PAIN IN ACL RECONSTRUCTED SUBJECTS

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    G. Hari Babu

    2014-10-01

    Full Text Available Background: Ligament injury accounts for nearly 40% of all injury problems in anterior cruciate ligament injury constitute nearly 50% of all knee ligament injuries. Anterior cruciate ligament deficiency affects not only the mobility, self-confidence and lifestyle of the affected persons in short term but also causes arithmetic changes in the affected knee in the long run. Purpose of study to find the effectiveness of concentric and eccentric for post anterior cruciate ligament reconstruction subjects on muscle strength, joint range of motion and pain. Methods: 24 samples with age group of 35 years were randomly assigned to two groups Concentric and Eccentric groups. The Concentric group, performed 9 (3sets concentric contractions for knee extensors and 9 concentric contractions for knee flexor muscles. The eccentric group done 9 (3 sets eccentric contractions for knee extensors and 9 eccentric contractions for knee flexors. Results: Pain is significantly decreased in concentric group. But not significantly decreased in eccentric group (t = 2.85, P = 0.009; and t = 1.40; P = 0.17. The range of motion is significantly increased in both concentric knee extension and flexion and eccentric knee extension and flexion (t = 3.53, P = 0.0023; and t = 4.55; P < 0.001. The quadriceps muscle strength is significantly improved in both concentric and eccentric groups at 60° / sec and 90° / sec. Conclusion: The eccentric exercises are better than concentric exercises in improving the strength of hamstring and quadriceps muscles.

  2. Comparison of the electromyographic activity, quadriceps: hamstring coactivation ratio and strength changes of dominant leg muscles in collegiate football and volleyball players during different forms of exercises

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    Tanzila Taj

    2015-10-01

    Full Text Available The preliminary study was aimed to compare Electromyographic (EMG activity, Quadriceps: Hamstring coactivation (Q: H ratio and 1- Repetition maximum (RM squat changes of dominant leg muscles in collegiate football and volleyball players during different forms of exercises. Surface EMG analysis was carried out in 24 university level trained male players, football (n=12 and volleyball (n=12 while performing the following exercises: unilateral bridges, lunges, lateral step up to a 20.32 cm (8 inch platform, quadruped arm/ lower extremity lift in the first session. The EMG activities of vastus medialis obliquus (VMO and hamstrings muscles of dominant leg of the players of both groups were recorded using Power Lab EMG system (Lab Chart, AD instruments, ML-818, Australia. On the next session, 1-RM squat tests were also performed on the same players of both groups. In footballers, the lateral step-up, lunges and quadruped arm/ lower extremity lift and in volleyball players, only lunges produced EMG levels greater than 45% maximum voluntary isometric contraction (MVIC in the VMO, which suggests that they may be beneficial for strengthening that muscle. All the exercises produced EMG levels less than 45% MVIC in hamstrings in both groups of players, so they may be more beneficial for training endurance and stabilization. The study also revealed smallest Q: H coactivation ratio in all exercises in volleyball players suggesting more hamstring activity than quadriceps but in footballers, moderate Q:H coactivation ratios were obtained establishing the quadriceps dominant activation in all these exercises. The 1- RM squat testing also showed significantly greater value (p=0.00 in football players than volleyball players. The findings in this study may be used to select specific exercises to enhance a core training program depending on the individual needs of an athlete or as per the requirement of the specific sport.

  3. Voluntary activation level and muscle fiber recruitment of human quadriceps during lengthening contractions.

    Science.gov (United States)

    Beltman, J G M; Sargeant, A J; van Mechelen, W; de Haan, A

    2004-08-01

    Voluntary activation levels during lengthening, isometric, and shortening contractions (angular velocity 60 degrees/s) were investigated by using electrical stimulation of the femoral nerve (triplet, 300 Hz) superimposed on maximal efforts. Recruitment of fiber populations was investigated by using the phosphocreatine-to-creatine ratio (PCr/Cr) of single characterized muscle fibers obtained from needle biopsies at rest and immediately after a series of 10 lengthening, isometric, and shortening contractions (1 s on/1 s off). Maximal voluntary torque was significantly higher during lengthening (270 +/- 55 N.m) compared with shortening contractions (199 +/- 47 N.m, P < 0.05) but was not different from isometric contractions (252 +/- 47 N.m). Isometric torque was higher than torque during shortening (P < 0.05). Voluntary activation level during maximal attempted lengthening contractions (79 +/- 8%) was significantly lower compared with isometric (93 +/- 5%) and shortening contractions (92 +/- 3%, P < 0.05). Mean PCr/Cr values of all fibers from all subjects at rest were 2.5 +/- 0.6, 2.0 +/- 0.7, and 2.0 +/- 0.7, respectively, for type I, IIa, and IIax fibers. After 10 contractions, the mean PCr/Cr values for grouped fiber populations (regardless of fiber type) were all significantly different from rest (1.3 +/- 0.2, 0.7 +/- 0.3, and 0.8 +/- 0.6 for lengthening, isometric, and shortening contractions, respectively; P < 0.05). The cumulative distributions of individual fiber populations after either contraction mode were significantly different from rest (P < 0.05). Curves after lengthening contractions were less shifted compared with curves from isometric and shortening contractions (P < 0.05), with a smaller shift for the type IIax compared with type I fibers in the lengthening contractions. The results indicate a reduced voluntary drive during lengthening contractions. PCr/Cr values of single fibers indicated a hierarchical order of recruitment of all fiber

  4. Effect of a high intensity quadriceps fatigue protocol on knee joint mechanics and muscle activation during gait in young adults.

    Science.gov (United States)

    Murdock, Gillian Hatfield; Hubley-Kozey, Cheryl L

    2012-02-01

    The purpose of this study was to determine the effect of impaired quadriceps function on knee joint biomechanics and neuromuscular function during gait. Surface electromyograms, three-dimensional motion and ground reaction forces were collected during gait before and after 20 healthy adults completed a high intensity quadriceps fatigue protocol. Pattern recognition techniques were utilized to examine changes in amplitude and temporal characteristics of all gait variables. The fatigue protocol resulted in decreased knee extensor torque generation and quadriceps median power frequencies for 18 of 20 participants (p gait data from these 18 participants was analyzed. The knee external rotation angle increased (p knee motion and loading characteristics were altered following a high intensity fatigue protocol in a manner that may place the knee joint at greater risk for joint pathology and injury.

  5. Effects of electrical muscle stimulation early in the quadriceps and tibialis anterior muscle of critically ill patients.

    Science.gov (United States)

    Falavigna, Letícia Ferreira; Silva, Michele Gonçalves; Freitas, Amanda Lopes de Almeida; Silva, Priscila Figueiredo dos Santos; Paiva Júnior, Marçal Durval Siqueira; de Castro, Célia Maria Machado Barbosa; Andrade, Maria do Amparo; Gallindo, Marcos Antonio Cavalcanti; Ribeiro, Luana Carneiro; Ramos, Francimar Ferrari; de Andrade, Flávio Maciel Dias; de França, Eduardo Eriko Tenório

    2014-05-01

    Electrical muscle stimulation (EMS) is applied to critically ill patients in order to improve their muscle strength, thereby preventing hypotrophy and promoting functional recovery. To assess the effects of early EMS on the range of movement of the ankle joint, and on thigh and leg circumference in critically ill patients. This is a prospective randomized clinical trial comprising 11 patients undergoing mechanical ventilation. Before and after EMS the thigh and leg circumference in both lower limbs and the goniometry of the tibiotarsal joint were measured. The angle of 90° on the goniometer was taken as the standard neutral position (NP), with the arm fixed on the lateral malleolus of the ankle joint. Other measurements, namely dorsiflexion and plantar flexion, referred to as mobile arm, were taken from the NP. These recordings were obtained following an active contraction of the patients' muscles. Compared with the electrostimulated limb, a difference in dorsiflexion of the control limb was observed (96.2 ± 24.9 versus 119.9 ± 14.1°; p = 0.01). A girth of 10 cm of the leg was found in limb reduction when compared to the electrostimulated one (24.7 ± 3.1 versus 26.4 ± 4.0 cm; p = 0.03). EMS used at low current intensity and for a short duration failed to prevent muscle atrophy in critically ill patients. However, we did find a significant improvement in active dorsiflexion of the ankle joint suggesting that it could help to prevent against stance plantar flexion in these patients.

  6. Muscle activation and blood flow do not explain the muscle length-dependent variation in quadriceps isometric endurance.

    Science.gov (United States)

    Kooistra, R D; de Ruiter, C J; de Haan, A

    2005-03-01

    We investigated the role of central activation in muscle length-dependent endurance. Central activation ratio (CAR) and rectified surface electromyogram (EMG) were studied during fatigue of isometric contractions of the knee extensors at 30 and 90 degrees knee angles (full extension = 0 degree). Subjects (n = 8) were tested on a custom-built ergometer. Maximal voluntary isometric knee extension with supramaximal superimposed burst stimulation (three 100-mus pulses; 300 Hz) was performed to assess CAR and maximal torque capacity (MTC). Surface EMG signals were obtained from vastus lateralis and rectus femoris muscles. At each angle, intermittent (15 s on 6 s off) isometric exercise at 50% MTC with superimposed stimulation was performed to exhaustion. During the fatigue task, a sphygmomanometer cuff around the upper thigh ensured full occlusion (400 mmHg) of the blood supply to the knee extensors. At least 2 days separated fatigue tests. MTC was not different between knee angles (30 degrees : 229.6 +/- 39.3 N.m vs. 90 degrees: 215.7 +/- 13.2 N.m). Endurance times, however, were significantly longer (P muscle length-related differences in metabolic cost.

  7. Local architecture of the vastus intermedius is a better predictor of knee extension force than that of the other quadriceps femoris muscle heads.

    Science.gov (United States)

    Ando, Ryosuke; Saito, Akira; Umemura, Yoshihisa; Akima, Hiroshi

    2015-09-01

    The purpose of this study was to determine whether the muscle architecture of each head of the quadriceps femoris (QF) at multiple regions can be used to predict knee extension force. Muscle thickness and pennation angle were measured using sonographic images from multiple regions on each muscle of the QF with the knee flexed to 90°. The fascicle lengths of the rectus femoris (RF), vastus lateralis (VL) and vastus intermedius (VI) muscles were estimated based on sonographic images taken along the length of the thigh. The muscle architecture of the vastus intermedius was determined in two separate locations using sonographic images of the anterior (ant-VI) and lateral portions (lat-VI). The maximal voluntary contraction (MVC) was measured during isometric knee extension at a knee joint angle of 90°. The relationship between MVC force and muscle architecture was examined using a stepwise linear regression analysis with MVC force as the dependent variable. The muscle thickness of the ant-VI was selected as an independent variable in the first step of the linear regression analysis (R(2) = 0.66, Parchitecture of the VI is the best predictor of knee extension force.

  8. Total rupture of the quadriceps muscle in an adolescent Ruptura total do músculo quadríceps em um adolescente

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    Rodrigo Pires e Albuquerque

    2013-01-01

    Full Text Available The total rupture of the quadriceps muscle in an adolescent is a rare lesion. We report a case of a 13 year old boy who suffered a direct trauma to the left knee. No predisposing factors have been diagnosed. The lesion was treated with surgical repair and transosseus sutures. The aim of this study was to present a rare case of rupture of the quadriceps muscle in an adolescent and the therapy used.A ruptura total do músculo quadríceps em um adolescente é uma lesão rara. Nós relatamos um caso de um menino de 13 anos que sofreu um trauma direto no joelho esquerdo. Não foram diagnosticados fatores predisponentes. A lesão foi tratada com o reparo cirúrgico e suturas transósseas. O objetivo desta pesquisa foi apresentar um caso raro de ruptura do músculo quadríceps em um adolescente e a terapêutica adotada.

  9. The dependence between clinical condition and value of the maximum force in the quadriceps femoris muscle during MVC test in patients with knee osteoarthritis.

    Science.gov (United States)

    Nowak, Karina; Sobota, Grzegorz; Bacik, Bogdan; Hajduk, Grzegorz; Kusz, Damian

    2012-01-01

    The aim of this study was to check whether there was a correlation between the value of the maximum developed torque of the quadriceps femoris muscle and subjective evaluation of a patient's pain which is measured by the VAS. Also evaluated were changes in the muscle torque value and KSS scale over time. For examining patient's condition use was made of a KSS scale (knee score: pain, range of motion, stability of joint and limb axis) before the surgery and in weeks 6 and 12, as well as 6 months after surgery. It was found to be constantly improving in comparison with the condition before the surgery. This is confirmed by a significant statistical value difference of KSS scale. The surgery substantially increases the quality of live and function recurrence.

  10. Effect of Electromyographic Biofeedback Training on Pain, Quadriceps Muscle Strength, and Functional Ability in Juvenile Rheumatoid Arthritis.

    Science.gov (United States)

    Eid, Mohamed Ahmed Mahmoud; Aly, Sobhy M; El-Shamy, Shamekh M

    2016-12-01

    To investigate the effects of electromyographic (EMG) biofeedback training on pain, quadriceps strength, and functional ability in juvenile rheumatoid arthritis (JRA). This is a randomized controlled study; 36 children (11 boys and 25 girls) with polyarticular JRA, with ages ranging from 8 to 13 years, were selected and assigned randomly, using computer-generated random numbers, into 2 groups. The control group (n = 18) received the conventional physical therapy program, whereas the study group (n = 18) received the same program as the control group in addition to EMG biofeedback-guided isometric exercises for 3 days a week for 12 weeks. Pain, peak torque of quadriceps strength, and functional ability were evaluated before, after 6 weeks, and at the end of 12 weeks of the treatment program. By 6 weeks, significant differences were observed in the study group (P strength, and functional ability (P strength, and functional performance in JRA.

  11. Quadriceps and patellar tendon rupture.

    Science.gov (United States)

    Ramseier, L E; Werner, C M L; Heinzelmann, M

    2006-06-01

    Ruptures of the patellar and/or quadriceps tendon are rare injuries that require immediate repair to re-establish knee extensor continuity and to allow early motion. We evaluated 36 consecutive patients with quadriceps or patellar tendon rupture between 1993 and 2000. There were 37 primary ruptures, 3 reruptures, 21 quadriceps and 19 patellar tendon ruptures. Follow up examination (>24 months postoperatively) included the patient's history, assessment of risk factors, clinical examination of both knees, isometric muscle strength measurements and three specific knee scores, Hospital for Special Surgery Score, Knee Society Score and Turba Score, and a short form SF-36. We evaluated 29 patients (26 men) with 33 ruptures (16 patellar tendon, 17 quadriceps tendon). Seven patients were lost to follow up. We found no difference between the range of motion and muscle strength when the injured leg was compared to the non-injured leg. Risk factors did not influence the four scores, patient satisfaction, pain, muscle strength or range of motion. Multiple injured patients had a significant reduction in muscle strength and circumference, however patient satisfaction did not differ to the non-multiple injured patient group.

  12. The Effects of Different Stretching Techniques of the Quadriceps Muscles on Agility Performance in Female Collegiate Soccer Athletes: A Pilot Study

    Science.gov (United States)

    Gillis, C. B.; Martinez, N. J.

    2008-01-01

    Background Stretching has long been an integral component of pre-performance activities for a multitude of athletic endeavors. Previous research has demonstrated that stretching may have detrimental effects on performance. Specific knowledge of the precise effects of stretching may influence the decision to appropriately apply stretching techniques in the sport and therapeutic settings. Objective The purpose of this pilot study was to examine the effects of static stretching, proprioceptive neuromuscular facilitation (contract-relax) stretching, and no stretching of the quadriceps muscle group on agility performance. Methods Twelve healthy, female, collegiate soccer players aged 18 – 25 performed one of the three stretching protocols (static, contract-relax, no stretch) and the agility test (T-test) on three non-consecutive days. Agility times were recorded and compared based on stretching technique and day that each test was performed. Results No significant difference was found among the means of the different stretching techniques. The t-test agility performance times were as follows: control, =9.7 seconds; static stretch, =9.73 seconds; and contract-relax, =9.62 seconds. Conclusion The results of this study suggest that agility performance may be independent of stretching technique of the quadriceps performed in female collegiate soccer athletes. It is recommended that female soccer athletes about to engage in agility activity may perform either no stretch, static stretch, or contract-relax stretching according to individual preference. PMID:21509139

  13. Isokinetic quadriceps and hamstring muscle strength and knee function 5 years after anterior cruciate ligament reconstruction: comparison between bone-patellar tendon-bone and hamstring tendon autografts.

    Science.gov (United States)

    Lautamies, Riitta; Harilainen, Arsi; Kettunen, Jyrki; Sandelin, Jerker; Kujala, Urho M

    2008-11-01

    Existing clinical studies have not proven which graft is to be preferred in anterior cruciate ligament (ACL) reconstruction. In recent years, bone-patellar tendon-bone and hamstring tendons have been the most frequently used graft types. Muscle strength deficit is one of the consequences after ACL reconstruction. The aim of this study was to evaluate possible differences in hamstring and quadriceps muscle strength and knee function 5 years after ACL reconstruction between the BPTB and the STG groups. The study group consisted of 288 patients (132 women, 156 men) with a unilateral ACL rupture who had received a BPTB (175 patients) or STG (113 patients) ACL reconstruction. Lower extremity concentric isokinetic peak extension and flexion torques were assessed at the angular velocities of 60 degrees /s and 180 degrees /s. The International Knee Documentation Committee (IKDC), the Tegner activity level, the Lysholm knee and the Kujala patellofemoral scores were also collected. Isokinetic quadriceps peak torque (percentage of the contralateral side) was 3.9% higher in the STG group than in the BPTB group at the velocity of 60 degrees /s and 3.2% higher at the velocity of 180 degrees /s and the isokinetic hamstring peak torque 2% higher in the BPTB group than in the STG group at the velocity of 60 degrees /s and 2.5% higher at the velocity of 180 degrees /s. In both groups the subjects had weaker quadriceps and hamstring muscle strength in the injured extremity compared with the uninjured one. In the single-leg hop test (according to the IKDC recommendations) there was a statistically significant difference (P = 0.040) between the groups. In the STG group, 68% of the patients had the single-leg hop ratio (injured vs. uninjured extremity) > or =90%, 31% of the patients 75-89% and 1% of the patients <75%, while in the BPTB group the corresponding percentages were 72, 21 and 7%. However, no statistically significant differences in clinical outcome were found between the

  14. Nature of the coupling between neural drive and force-generating capacity in the human quadriceps muscle.

    Science.gov (United States)

    Hug, François; Goupille, Clément; Baum, Daniel; Raiteri, Brent J; Hodges, Paul W; Tucker, Kylie

    2015-11-22

    The force produced by a muscle depends on both the neural drive it receives and several biomechanical factors. When multiple muscles act on a single joint, the nature of the relationship between the neural drive and force-generating capacity of the synergistic muscles is largely unknown. This study aimed to determine the relationship between the ratio of neural drive and the ratio of muscle force-generating capacity between two synergist muscles (vastus lateralis (VL) and vastus medialis (VM)) in humans. Twenty-one participants performed isometric knee extensions at 20 and 50% of maximal voluntary contractions (MVC). Myoelectric activity (surface electromyography (EMG)) provided an index of neural drive. Physiological cross-sectional area (PCSA) was estimated from measurements of muscle volume (magnetic resonance imaging) and muscle fascicle length (three-dimensional ultrasound imaging) to represent the muscles' force-generating capacities. Neither PCSA nor neural drive was balanced between VL and VM. There was a large (r = 0.68) and moderate (r = 0.43) correlation between the ratio of VL/VM EMG amplitude and the ratio of VL/VM PCSA at 20 and 50% of MVC, respectively. This study provides evidence that neural drive is biased by muscle force-generating capacity, the greater the force-generating capacity of VL compared with VM, the stronger bias of drive to the VL.

  15. Effect of ThermaCare HeatWraps and Icy Hot Cream/Patches on Skin and Quadriceps Muscle Temperature and Blood Flow.

    Science.gov (United States)

    Petrofsky, Jerrold Scott; Laymon, Michael; Berk, Lee; Bains, Gurinder

    2016-03-01

    The purpose of this study was to compare the effects of over-the-counter treatments-ThermaCare HeatWraps (chemical reaction to produce heat above the skin), Icy Hot Patch, and Icy Hot Cream (topically applied menthol)-on skin and deep tissue temperature. This was a longitudinal crossover study. On each of 3 days, a ThermaCare HeatWrap, Icy Hot Cream, or Icy Hot Patch was applied randomly over the quadriceps muscle in 15 healthy volunteers with normal body mass. Skin and muscle temperature and blood flow were measured by laser flowmetry every 15 minutes for 2 hours. After 2 hours, mean temperature decreased by 2.1°C (7.0%; P = .02) in skin and 1.0°C (2.9%; P = .01) in muscle with Icy Hot Cream. Icy Hot Patch decreased skin and muscle temperature by 1.7°C (5.4%; P = .03) and 1.3°C (3.8%; P = .01), respectively. In contrast, ThermaCare raised skin and muscle temperature by 7.8°C (25.8%; P = .001) and 2.7°C (7.7%; P = .002), respectively; both were significantly warmer with ThermaCare vs either Icy Hot product (all P Cream: 56.7 flux [39.3%; P = .003]; Patch: 19.1 flux [16.7%; P = .045]). Muscle blood flow decreased with the Patch (6.7 flux [7.0%; P = .02]). After a period of fluctuations, Icy Hot Cream produced a net increase vs baseline of 7.0 flux (16.9%; P = .02). ThermaCare more than doubled blood flow in skin (83.3 flux [109.7%; P = .0003]) and muscle (25.1 flux [148.5%; P = .004]). In this group of 15 healthy volunteers, ThermaCare HeatWraps provided the greatest degree of tissue warming and increase in tissue blood flow.

  16. Comparison of quadriceps-sparing minimally invasive and medial parapatellar total knee arthroplasty: A 2-year follow-up study

    Directory of Open Access Journals (Sweden)

    Hongsen Chiang

    2012-12-01

    Conclusions: Patients undergoing quadriceps-sparing and standard medial parapatellar TKA had comparable outcomes for quadriceps muscle strength, hamstring–quadriceps balance, and knee function; however, the quadriceps-sparing TKA was more time consuming surgically and resulted in a less accurate prosthesis position.

  17. Exercise training induces similar elevations in the activity of oxoglutarate dehydrogenase and peak oxygen uptake in the human quadriceps muscle

    DEFF Research Database (Denmark)

    Blomstrand, Eva; Krustrup, Peter; Søndergaard, Hans

    2011-01-01

    During exercise involving a small muscle mass, peak oxygen uptake is thought to be limited by peripheral factors, such as the degree of oxygen extraction from the blood and/or mitochondrial oxidative capacity. Previously, the maximal activity of the Krebs cycle enzyme oxoglutarate dehydrogenase has...

  18. Changes in calsequestrin, TNF-α, TGF-β and MyoD levels during the progression of skeletal muscle dystrophy in mdx mice: a comparative analysis of the quadriceps, diaphragm and intrinsic laryngeal muscles.

    Science.gov (United States)

    Barros Maranhão, Juliana; de Oliveira Moreira, Drielen; Maurício, Adriana Fogagnolo; de Carvalho, Samara Camaçari; Ferretti, Renato; Pereira, Juliano Alves; Santo Neto, Humberto; Marques, Maria Julia

    2015-10-01

    In Duchenne muscular dystrophy (DMD), the search for new biomarkers to follow the evolution of the disease is of fundamental importance in the light of the evolving gene and pharmacological therapies. In addition to the lack of dystrophin, secondary events including changes in calcium levels, inflammation and fibrosis greatly contribute to DMD progression and the molecules involved in these events may represent potential biomarkers. In this study, we performed a comparative evaluation of the progression of dystrophy within muscles that are differently affected by dystrophy (diaphragm; DIA and quadriceps; QDR) or spared (intrinsic laryngeal muscles) using the mdx mice model of DMD. We assessed muscle levels of calsequestrin (calcium-related protein), tumour necrosis factor (TNF-α; pro-inflammatory cytokine), tumour growth factor (TGF-β; pro-fibrotic factor) and MyoD (muscle proliferation) vs. histopathology at early (1 and 4 months of age) and late (9 months of age) stages of dystrophy. Fibrosis was the primary feature in the DIA of mdx mice (9 months: 32% fibrosis), which was greater than in the QDR (9 months: 0.6% fibrosis). Muscle regeneration was the primary feature in the QDR (9 months: 90% of centrally nucleated fibres areas vs. 33% in the DIA). The QDR expressed higher levels of calsequestrin than the DIA. Laryngeal muscles showed normal levels of TNF-α, TGF-β and MyoD. A positive correlation between histopathology and cytokine levels was observed only in the diaphragm, suggesting that TNF-α and TGF-β serve as markers of dystrophy primarily for the diaphragm.

  19. Kinesiology Taping does not Modify Electromyographic Activity or Muscle Flexibility of Quadriceps Femoris Muscle: A Randomized, Placebo-Controlled Pilot Study in Healthy Volleyball Players.

    Science.gov (United States)

    Halski, Tomasz; Dymarek, Robert; Ptaszkowski, Kuba; Słupska, Lucyna; Rajfur, Katarzyna; Rajfur, Joanna; Pasternok, Małgorzata; Smykla, Agnieszka; Taradaj, Jakub

    2015-08-01

    Kinesiology taping (KT) is a popular method of supporting professional athletes during sports activities, traumatic injury prevention, and physiotherapeutic procedures after a wide range of musculoskeletal injuries. The effectiveness of KT in muscle strength and motor units recruitment is still uncertain. The objective of this study was to assess the effect of KT on surface electromyographic (sEMG) activity and muscle flexibility of the rectus femoris (RF), vastus lateralis (VL), and vastus medialis (VM) muscles in healthy volleyball players. Twenty-two healthy volleyball players (8 men and 14 women) were included in the study and randomly assigned to 2 comparative groups: "kinesiology taping" (KT; n=12; age: 22.30 ± 1.88 years; BMI: 22.19 ± 4.00 kg/m(2)) in which KT application over the RF muscle was used, and "placebo taping" (PT; n=10; age: 21.50 ± 2.07 years; BMI: 22.74 ± 2.67 kg/m(2)) in which adhesive nonelastic tape over the same muscle was used. All subjects were analyzed for resting sEMG activity of the VL and VM muscles, resting and functional sEMG activity of RF muscle, and muscle flexibility of RF muscle. No significant differences in muscle flexibility of the RF muscle and sEMG activity of the RF, VL, and VM muscles were registered before and after interventions in both groups, and between the KT and PT groups (p>0.05). The results show that application of the KT to the RF muscle is not useful to improve sEMG activity.

  20. The influence of patellar tendon and muscle-tendon unit stiffness on quadriceps explosive strength in man.

    Science.gov (United States)

    Massey, Garry J; Balshaw, Thomas G; Maden-Wilkinson, Thomas M; Tillin, Neale A; Folland, Jonathan P

    2017-02-15

    The influence of musculotendinous tissue stiffness on contractile rate of torque development (RTD) remains opaque. This study examined the relationships between both patellar tendon (PT) and vastus lateralis (VL) muscle-tendon unit (MTU) stiffness, and voluntary and evoked knee extension RTD. Fifty-two healthy untrained males completed duplicate laboratory sessions. Absolute and relative RTD was measured at 50 Nm/25%MVT increments from onset and sequentially during explosive voluntary and evoked octet (supramaximal stimulation: [8 pulses at 300 Hz]) isometric contractions. Isometric maximum voluntary torque (MVT) was also assessed. PT and MTU stiffness were derived from simultaneous force and ultrasound recordings of the PT and VL aponeurosis during constant RTD ramp contractions. Absolute and relative (to MVT and resting tissue length) stiffness (k) was measured over identical torque increments as RTD. Pearson's correlations tested relationships between stiffness and RTD measurements over matching absolute/relative torque increments. Absolute and relative PT k was unrelated to equivalent voluntary or evoked RTD (r = 0.020.255, P = 0.069-0.891). Absolute MTU k was unrelated to voluntary or evoked RTD (r ≤ 0.191, P ≥ 0.184), however some measures of relative MTU k were related to relative voluntary/evoked RTD (e.g. RTD25-50%MVT r = 0.374/0.353, P = 0.007/0.014). In conclusion, relative MTU k explained a small proportion of the variance in relative voluntary and evoked RTD (both ≤19%), despite no association of absolute MTU k or absolute/relative PT k with equivalent RTD measures. Therefore the muscle-aponeurosis component, but not free tendon was associated with relative RTD, although it seems an overriding influence of MVT negated any relationship of absolute MTU k and absolute RTD. This article is protected by copyright. All rights reserved.

  1. The Effect of Warm-Up and Cool-Down Exercise on Delayed Onset Muscle Soreness in the Quadriceps Muscle: a Randomized Controlled Trial

    Science.gov (United States)

    Olsen, Olav; Sjøhaug, Mona; van Beekvelt, Mireille; Mork, Paul Jarle

    2012-01-01

    The aim of the present study was to investigate the effect of warm-up and cool-down exercise on delayed onset of muscle soreness at the distal and central parts of rectus femoris following leg resistance exercise. Thirty-six volunteers (21 women, 15 men) were randomly assigned to the warm-up (20 min ergometer cycling prior to the resistance exercise), cool-down (20 min cycling after the resistance exercise), or control group performing resistance exercise only. The resistance exercise consisted of front lunges (10×5 repetitions/sets) with external loading of 40% (women) and 50% (men) of body mass. Primary outcomes were pressure pain threshold along rectus femoris and maximal isometric knee extension force. Data were recorded before the resistance exercise and on the two consecutive days. Pressure pain threshold at the central muscle belly was significantly reduced for the control group on both day 2 and 3 (p≤0.003) but not for the warm-up group (p≥0.21). For the cool-down group, pressure pain threshold at the central muscle belly was significantly reduced on day 2 (p≤0.005) and was also lower compared to the warm-up group (p=0.025). Force was significantly reduced on day 2 and 3 for all groups (p<0.001). This study indicates that aerobic warm-up exercise performed prior to resistance exercise may prevent muscle soreness at the central but not distal muscle regions, but it does not prevent loss of muscle force. PMID:23486850

  2. Relationships of quadriceps femoris muscle strength along with osteoporosis and knee osteoarthritis%股四头肌肌力及骨质疏松与膝骨关节炎的关系

    Institute of Scientific and Technical Information of China (English)

    刘康妍; 胡海澜; 陈勇; 金晶

    2016-01-01

    Objective To evaluate the relationships of quadriceps femoris muscle strength , osteoporosis, and knee osteoarthritis ( OA) through the study of quadriceps femoris muscle strength and bone mineral density (BMD) of 374 subjects.Methods From October 2013 to December, 374 patients of the Second Affiliated Hospital of Guangzhou Medical University 2015 were included.The age, weight, height of the patients were recorded .Following the weight-bearing anteroposterior radiographic examination of the knee , the patients were divided into the normal group ( 174 cases ) and the knee OA group ( 200 cases) according to the diagnostic criteria of knee osteoarthritis .(“Guide for Diagnosis Treatment of Osteoarthrits”) .The patients from knee OA group were classified into five levels according to Kellgre-Lawrence grade classification standard , and divided into the mild, the moderate, and the severe subgroups according to their clinical symptoms as well as X-ray performance .BMD was examined; the maximum strength of quadriceps femoris muscle was examined by measurement and analysis of muscle function as well as isometric dynamometer test .By comparing and analyzing different severity degrees of the knee OA group and the normal group though analysis of variance , Kruskal-Wallis test and Bonferroni method by SPSS software 13.0, the relationships of lower limb muscle attenuation , BMD, and knee OA were evaluated . Results In knee OA disease group , the patients classified with severe knee OA were associated with osteoporosis and quadriceps femoris muscle strength decrease . Data differences in hip bone BMD , quadriceps maximum muscle strength and average muscle strength of the involving limbs among the severe group, the normal group (P<0.05) and the mild knee OA group (P<0.05) were statistically significant. Conclusions The patients with degenerative joint disease are often associated with systemic osteoporosis and quadriceps femoris muscle strength declination .The severity of

  3. Reconstruction of neglected patellar tendon ruptures using the quadriceps graft.

    Science.gov (United States)

    Gomes, João Luiz Ellera; de Oliveira Alves, Jairo André; Zimmermann, José Mauro

    2014-08-01

    Several techniques using different grafts have been described for reconstruction of the patellar tendon after a neglected rupture. Retraction of the quadriceps tendon may compromise repair integrity due to progressive stretching of the graft. The authors present a surgical technique using the central one-third of the quadriceps tendon. This is supported by the fact that the resistance to traction of this segment of the quadriceps tendon equals that of a double-looped semitendinosus graft and that the harvesting of this specific graft promotes muscle inhibition, thus protecting the reconstruction during the recovery period.

  4. Partial tear of the quadriceps tendon in a child

    Energy Technology Data Exchange (ETDEWEB)

    Khanna, Geetika; El-Khoury, George [University of Iowa Hospitals and Clinics, Department of Radiology, Iowa City, IA (United States)

    2008-06-15

    We present a case of partial rupture of the quadriceps tendon in an 8-year-old girl. This is one of the youngest patients reported with a quadriceps tendon rupture, an entity seen predominantly in middle-aged people. The strength of the muscle tendon unit in a child makes tendon injuries extremely unusual as compared to apophyseal avulsions. The MR imaging findings of this unusual pediatric injury are illustrated. (orig.)

  5. Partial tear of the quadriceps tendon in a child.

    Science.gov (United States)

    Khanna, Geetika; El-Khoury, George

    2008-06-01

    We present a case of partial rupture of the quadriceps tendon in an 8-year-old girl. This is one of the youngest patients reported with a quadriceps tendon rupture, an entity seen predominantly in middle-aged people. The strength of the muscle tendon unit in a child makes tendon injuries extremely unusual as compared to apophyseal avulsions. The MR imaging findings of this unusual pediatric injury are illustrated.

  6. CONTRIBUTION OF HAMSTRING FATIGUE TO QUADRICEPS INHIBITION FOLLOWING LUMBAR EXTENSION EXERCISE

    Directory of Open Access Journals (Sweden)

    Joseph M. Hart

    2006-03-01

    Full Text Available The purpose of this study was to determine the contribution of hamstrings and quadriceps fatigue to quadriceps inhibition following lumbar extension exercise. Regression models were calculated consisting of the outcome variable: quadriceps inhibition and predictor variables: change in EMG median frequency in the quadriceps and hamstrings during lumbar fatiguing exercise. Twenty-five subjects with a history of low back pain were matched by gender, height and mass to 25 healthy controls. Subjects performed two sets of fatiguing isometric lumbar extension exercise until mild (set 1 and moderate (set 2 fatigue of the lumbar paraspinals. Quadriceps and hamstring EMG median frequency were measured while subjects performed fatiguing exercise. A burst of electrical stimuli was superimposed while subjects performed an isometric maximal quadriceps contraction to estimate quadriceps inhibition after each exercise set. Results indicate the change in hamstring median frequency explained variance in quadriceps inhibition following the exercise sets in the history of low back pain group only. Change in quadriceps median frequency explained variance in quadriceps inhibition following the first exercise set in the control group only. In conclusion, persons with a history of low back pain whose quadriceps become inhibited following lumbar paraspinal exercise may be adapting to the fatigue by using their hamstring muscles more than controls

  7. Foam Rolling of Quadriceps Decreases Biceps Femoris Activation.

    Science.gov (United States)

    Cavanaugh, Mark Tyler; Aboodarda, Saied Jalal; Hodgson, Daniel; Behm, David George

    2016-09-06

    Foam rolling has been shown to increase range of motion without subsequent performance impairments of the rolled muscle, however, there are no studies examining rolling effects on antagonist muscles. The objective of this study was to determine whether foam rolling the hamstrings and/or quadriceps would affect hamstrings and quadriceps activation in men and women. Recreationally active men (n=10, 25 ± 4.6 years, 180.1 ± 4.4 cm, 86.5 ± 15.7 kg) and women (n=8, 21.75 ± 3.2 years, 166.4 ± 8.8 cm, 58.9 ± 7.9 kg) had surface electromyographic activity analyzed in the dominant vastus lateralis (VL), vastus medialis (VM), and biceps femoris (BF) muscles upon a single leg landing from a hurdle jump under four conditions. Conditions included rolling of the hamstrings, quadriceps, both muscle groups and a control session. BF activation significantly decreased following quadriceps foam rolling (F(1,16) = 7.45, p = 0.015, -8.9%). There were no significant changes in quadriceps activation following hamstrings foam rolling. This might be attributed to the significantly greater levels of perceived pain with quadriceps rolling applications (F(1,18) = 39.067, p foam rolling for VL (F(6,30) = 1.31, p = 0.283) VM (F(6,30) = 1.203, p = 0.332) or BF (F(6,36) = 1.703, p = 0.199). Antagonist muscle activation may be altered following agonist foam rolling, however, it can be suggested that any changes in activation are likely a result of reciprocal inhibition due to increased agonist pain perception.

  8. Effect of time-dependent cryotherapy on redox balance of quadriceps injuries.

    Science.gov (United States)

    Silva, Marco Aurélio dos Santos; Carvalho, Taiara Ramos de; Cruz, Amanda Cristina Marques Barros da; Jesus, Lennon Rafael Guedine de; Silva Neto, Larissa Alexsandra da; Trajano, Eduardo Tavares Lima; Bezerra, Frank Silva

    2016-02-01

    Muscle trauma represents a high number of injuries in professional sport and recreation and may occur through several mechanisms. This study aims at analyzing time-dependent effects of cryotherapy on the redox balance in lesioned quadriceps muscles in F1 mice. Twenty male F1 mice were divided into five groups: (a) animals were not subjected to muscle lesioning or treatment (CTR); (b) quadriceps muscle was lesioned without treatment (L); (c) quadriceps muscle was lesioned and treated with cryotherapy for 5 min (LC5); (d) quadriceps muscle was lesioned and treated with cryotherapy for 20 min (LC20); and quadriceps muscle was lesioned and treated with cryotherapy for 40 min (LC40). The mice were euthanized; the quadriceps muscles were collected and subjected to analyses for levels of protein, hydroperoxides, nitrite, catalase (CAT) activity, oxidized glutathione (GSSG) and reduced glutathione (GSH). Protein levels were reduced in L (-39%; p cryotherapy does not improve the oxidative stress in lesioned muscles.

  9. [Quadriceps and patellar tendon ruptures].

    Science.gov (United States)

    Grim, C; Lorbach, O; Engelhardt, M

    2010-12-01

    Ruptures of the quadriceps or patellar tendon are uncommon but extremely relevant injuries. Early diagnosis and surgical treatment with a stable suture construction are mandatory for a good postoperative clinical outcome. The standard methods of repair for quadriceps and patellar tendon injuries include the placement of suture loops through transpatellar tunnels. Reinforcement with either a wire cerclage or a PDS cord is used in patellar tendon repair. The PDS cord can also be applied as augmentation in quadriceps tendon repair. In secondary patellar tendon repair an autologous semitendinosus graft can be used. For chronic quadriceps tendon defects a V-shaped tendon flap with a distal footing is recommended. The different methods of repair should lead to early functional postoperative treatment. The clinical outcome after surgical treatment of patellar and quadriceps tendon ruptures is mainly good.

  10. Quadriceps tendon injuries

    Directory of Open Access Journals (Sweden)

    Ristić Vladimir

    2013-01-01

    Full Text Available Introduction. The aim of study was to analyze risk factors, mechanisms of injury, symptoms and time that elapsed from injury until operation of complete quadriceps tendon ruptures. Material and Methods. This retrospective multicenter study included 30 patients operated for this injury, of whom 28 (93.3% were men. The average age was 53.7 years (18-73. Twenty-six patients had reconstruction of unilateral rupture and four of bilateral one. Results. Eighty percent of them had some risk factors for rupture of the tendon with degenerative changes. Eight patients had diabetes, seven patients were on renal dialysis, two patients had secondary hyperparathyroidism, five patients were obese and two patients had former knee operations. These injuries occurred in 80% following minor trauma caused by falls on stairs, on flat surfaces and squatting. The most frequent symptoms were: pain, swelling, lack of extension of knee and defect above patella, and three cases were initially misdiagnosed. During the first 10 days after injury, acute and chronic ruptures were reconstructed in 22 (73.3% and 8 patients, respectively. Conclusion. Quadriceps tendon injuries most often happen to male patients with predisposing conditions in their fifth and sixth decade of life due to trivial trauma. Patients on renal dialysis are the most vulnerable population group.

  11. Different Load Endurance Training Effect on Rat's Quadriceps Muscles' Nitric Oxide and Iron%不同负荷耐力训练对大鼠股四头肌一氧化氮及铁的影响

    Institute of Scientific and Technical Information of China (English)

    何敬和; 刘冠男; 常震; 姚丽

    2012-01-01

    To observe rat skeletal muscle's nitric oxide(NO) levels, changes in iron metabolism in skeletal muscle and its correlation after endurance training with different loads. To study different loads of NO in rat skeletal muscle during endurance training the regulatory mechanisms of iron metabolism. 21 male wistar rats were randomly divided into control group, moderate exercise group and strenuously exercised group. Control rats did not do exercise. Another two groups of rats were carried out in different load incremental treadmill training. After 5 weeks, the muscle quadriceps iron content,nitric oxide synthase( NOS) activity and NO content were determined. Serum NOS activity and NO content of excessive exercise group were significantly higher than those in the control group and the moderate exercise group (P<0.01) ; Quadriceps NOS activity and NO content were significantly higher than that of control group (P <0.01) ; The organization iron of excessive exercise group was significant higher than those in the control group and moderate exercise group (P<0.01) ;The NOS activity and NO content of moderate exercise group serum were significantly higher than that in control group (P<0.01) ; Quadriceps NO content was higher than those in the control group (P <0.01) ; The organization iron of moderate exercise group content was significantly higher than that in control group ( P < 0. 01). Moderate exercise - induced increase in serum and quadriceps NOS is the result of increased NO levels. NO makes intake of iron within cells increased, extracellular transport of iron reduced, and ultimately the muscle cells of the storage iron increases to ensure the needs of iron in skeletal muscle movement, so that the body can get a beneficial physiological adaptations when doing exercise.%观察大鼠不同负荷耐力训练后骨骼肌一氧化氮(NO)含量、骨骼肌铁代谢及其相关关系,研究NO对不同负荷耐力训练过程中大鼠骨骼肌铁代

  12. Identification of quadriceps-shank dynamics using randomized interpulse interval stimulation

    NARCIS (Netherlands)

    Franken, Henry M.; Veltink, Peter H.; Tijsmans, Roel; Nijmeijer, Henk; Boom, Herman B.K.

    1995-01-01

    Model structures for artificially stimulated paralyzed muscle-limb system dynamics were developed and experimentally evaluated in paraplegic patients. The examined system consisted of the quadriceps, electrically stimulated using surface electrodes, and a freely swinging shank. The interpulse interv

  13. 中国女子曲棍球运动员膝关节伸、屈肌群等速力量测试研究%Isokinetic strength of hamstring and quadriceps muscles in Chinese women hockey players

    Institute of Scientific and Technical Information of China (English)

    付颖; 闫琪

    2011-01-01

    通过对19名国家女子曲棍球队队员膝关节伸屈肌群的等速力量测试,探讨我国优秀女曲队员的下肢力量特点,为科学训练提供依据.结果表明:我国优秀女子曲棍运动员下肢屈肌力量较强,屈肌和伸肌群力量之间的比率(H/Q)比较合理;仅快速运动时(300°/s)弱侧屈膝肌群力量相对较弱,需加强该侧屈肌快速力量训练.%The isokinetic strength of hamstring and quadriceps muscles of 19 elite Chinese women hockey players were determined using Cybex 6000 system.The results indicated that the ratio of H/Q in these players was reasonable;the isokinetic strength of left knee flexors was lower at 300°/sec,and this speed strength would be enhanced.

  14. Knee flexion with quadriceps cocontraction: A new therapeutic exercise for the early stage of ACL rehabilitation.

    Science.gov (United States)

    Biscarini, Andrea; Contemori, Samuele; Busti, Daniele; Botti, Fabio M; Pettorossi, Vito E

    2016-12-08

    Quadriceps strengthening exercises designed for the early phase of anterior cruciate ligament (ACL) rehabilitation should limit the anterior tibial translation developed by quadriceps contraction near full knee extension, in order to avoid excessive strain on the healing tissue. We hypothesize that knee-flexion exercises with simultaneous voluntary contraction of quadriceps (voluntary quadriceps cocontraction) can yield considerable levels of quadriceps activation while preventing the tibia from translating forward relative to the femur. Electromyographic activity in quadriceps and hamstring muscles was measured in 20 healthy males during isometric knee-flexion exercises executed near full knee extension with maximal voluntary effort of quadriceps cocontraction and external resistance (R) ranging from 0% to 60% of the 1-repetition maximum (1RM). Biomechanical modeling was applied to derive the shear (anterior/posterior) tibiofemoral force developed in each exercise condition. Isometric knee-flexion exercises with small external resistance (R=10% 1RM) and maximal voluntary effort of quadriceps cocontraction yielded a net posterior (ACL-unloading) tibial pull (P=0.005) and levels of activation of 32%, 50%, and 45% of maximum voluntary isometric contraction, for the rectus femoris, vastus medialis, and vastus lateralis, respectively. This exercise might potentially rank as one of the most appropriate quadriceps strengthening interventions in the early phase of ACL rehabilitation. Copyright © 2016 Elsevier Ltd. All rights reserved.

  15. Correlation between Quadriceps Endurance and Adduction Moment in Medial Knee Osteoarthritis.

    Directory of Open Access Journals (Sweden)

    Soon-Hyuck Lee

    Full Text Available It is not clear whether the strength or endurance of thigh muscles (quadriceps and hamstring is positively or negatively correlated with the adduction moment of osteoarthritic knees. This study therefore assessed the relationships between the strength and endurance of the quadriceps and hamstring muscles and adduction moment in osteoarthritic knees and evaluated predictors of the adduction moment. The study cohort comprised 35 patients with unilateral medial osteoarthritis and varus deformity who were candidates for open wedge osteotomy. The maximal torque (60°/sec and total work (180°/sec of the quadriceps and hamstring muscles and knee adduction moment were evaluated using an isokinetic testing device and gait analysis system. The total work of the quadriceps (r = 0.429, P = 0.037 and hamstring (r = 0.426, P = 0.045 muscles at 180°/sec each correlated with knee adduction moment. Preoperative varus deformity was positively correlated with adduction moment (r = 0.421, P = 0.041. Multiple linear regression analysis showed that quadriceps endurance at 180°/sec was the only factor independently associated with adduction moment (β = 0.790, P = 0.032. The adduction moment of osteoarthritic knees correlated with the endurance, but not the strength, of the quadriceps muscle. However, knee adduction moment did not correlate with the strength or endurance of the hamstring muscle.

  16. EFFECTIVENESS OF DIFFERENT QUADRICEPS STRENGTHENING PROTOCOLS IN IMPROVEMENT OF EXTENSOR LAG IN OSTEOARTHRITIC KNEE JOINT

    Directory of Open Access Journals (Sweden)

    Mayank Shukla

    2010-09-01

    Full Text Available Introduction: Osteoarthritis of knee is a widespread, slowly developing disease with a high prevalence with age, with greater body weight and in post menopausal women. The main causes of functional dysfunction in osteoarthritic knee are pain and quadriceps muscle weakness. Physical rehabilitation usually includes quadriceps exercises i.e. isometric and isotonic exercises for the maintenance of joint range of motion and muscle strength. Biofeedback is a process that can be combined with it to increase the awareness about the extent of muscle work done by quadriceps muscle. The aim of the study was to compare the effectiveness of different quadriceps strengthening protocols with or without biofeedback in improvement of extensor lag in osteoarthritic knee joint. Materials & Methods: Sixty osteoarthritic knee patients with twenty patients each in three groups were randomly selected from Guru Harkrishan Hospital, Sarai Kale khan and Physical rehabilitation clinics in Delhi. Patients were randomly divided into three groups A, B and C. Research Design was Experimental study. Dependent Variables were Quardiceps Lag and Knee ROM .Independent Variables were Biofeedback and Modified Quadriceps Exercise which were introduced to the subjects. ANOVA test was applied to find out the statistical level of significance. Results: There was a great improvement of extensor lag in group C who had received Modified Quadriceps Sets with Biofeedback when compared with group B and group A. The percentage of reduction in pain was more and ROM was more increased in group C when compared with group B and A. Discussion & Conclusion: Modified quadriceps sets with biofeedback are better than the quadriceps sets and quadriceps sets with biofeedback in improvement of extensor lag in osteoarthric knee patients.

  17. The effect of high-resistance training on the strength and cross-sectional area of the human quadriceps.

    Science.gov (United States)

    Young, A; Stokes, M; Round, J M; Edwards, R H

    1983-10-01

    Seventeen volunteers performed unilateral strength-training of the quadriceps with high-resistance, low-repetition, dynamic exercise, thrice weekly for an average of 5 weeks. Both before and after the training period, bilateral measurements were made of isometric quadriceps strength, quadriceps cross-sectional area (by ultrasound scanning), and thigh circumference. There were no significant changes in the untrained thighs. The trained quadriceps increased their isometric strength by more than they changed their cross-sectional area (mean increments = 15% and 6% respectively). Quadriceps hypertrophy was underestimated by measurements of thigh circumference and could not be predicted from them. We conclude that studies of localized muscle growth require direct measurements of the size of the muscle(s) concerned. Nevertheless, these may still underestimate the improvements in strength produced by high-resistance training.

  18. Delayed presentation of compartment syndrome of the thigh secondary to quadriceps trauma and vascular injury in a soccer athlete

    Directory of Open Access Journals (Sweden)

    Moo Ing How

    2015-01-01

    Conclusion: A high index of suspicion for compartment syndrome is needed in all severe quadriceps contusion. Vascular injury can cause thigh compartment syndrome in sports trauma. MRI findings of deep thigh muscle swelling and “blow-out” tear of the vastus lateralis are strongly suggestive of severe quadriceps injury, and may be a harbinger of delayed thigh compartment syndrome.

  19. Quadriceps and hamstrings morphology is related to walking mechanics and knee cartilage MRI relaxation times in young adults.

    Science.gov (United States)

    Kumar, Deepak; Subburaj, Karupppasamy; Lin, Wilson; Karampinos, Dimitrios C; McCulloch, Charles E; Li, Xiaojuan; Link, Thomas M; Souza, Richard B; Majumdar, Sharmila

    2013-12-01

    Controlled laboratory study using a cross-sectional design. To analyze the relationship of quadriceps-hamstrings and medial-lateral quadriceps anatomical cross-sectional area (ACSA) ratios with knee loads during walking and articular and meniscal cartilage composition in young, healthy subjects. Muscle forces affect knee loading during walking, but it is not known if muscle morphology is associated with walking mechanics and cartilage composition in young subjects. Forty-two knees from 27 young, healthy, active volunteers (age, 20-35 years; body mass index, relaxation times and for quadriceps and hamstrings muscle ACSA. Frontal plane kinetics during the stance phase of walking was calculated. Generalized estimating equation models were used to identify muscle variables that predicted MRI and gait parameters. Quadriceps-hamstrings and medial-lateral quadriceps ACSA ratios were positively related to frontal plane loading (β = .21-.54, P≤.006), global articular cartilage relaxation times (β = .22-.28, P≤.041), and the medial-lateral ratio of meniscus T1rho relaxation time (β = .26-.36, P≤.049). The medial-lateral quadriceps ACSA ratio was positively related to global meniscus T1rho relaxation times (β = .30, P = .046). Higher quadriceps-hamstrings and medial-lateral quadriceps ACSA ratios were associated with higher frontal plane loading during walking and with articular and meniscal cartilage T1rho and T2 relaxation times. These findings highlight the relationships between different knee tissues and knee mechanics in young, healthy individuals.

  20. Age-graded reductions in quadriceps muscle strength and peak aerobic capacity in COPD Reduções graduadas por idade na força muscular do quadríceps e no pico de consumo de oxigênio na DPOC

    Directory of Open Access Journals (Sweden)

    Martijn A. Spruit

    2012-04-01

    Full Text Available BACKGROUND: Reductions in quadriceps strength and peak aerobic capacity (VO2 in patients with chronic obstructive pulmonary disease (COPD have been studied in relatively small samples over a short period. Moreover, results were not corrected for confounding variables, such as lean muscle mass, gender, and gas transfer capacity of the lungs. OBJECTIVES: To compare quadriceps muscle strength and peak V.O2 in women and men while stratifying for age and gas transfer capacity. We then corrected for lower-limb lean muscle mass to see whether and to what extent the age-graded reduction remained evident. METHODS: Retrospectively, data of 374 women and 593 men with COPD were analyzed: lung function, current drug therapy, quadriceps strength, peak V.O2, lower-limb lean muscle mass, and gas transfer capacity. RESULTS: Quadriceps strength and peak V.O2 were lower in older women and men with a gas transfer capacity of 50% predicted. Yet, counter to our hypothesis, lower-limb lean muscle mass did not show an age-graded reduction and, in turn, could not account for the relationship of age with quadriceps strength and peak V.O2. CONCLUSIONS: It is apparent that there is an age-graded reduction in skeletal muscle function in patients with COPD. Therefore, prevention of an age-graded decline in quadriceps muscle strength and peak V.O2 may need to become an outcome of pulmonary rehabilitation of patients with COPD.CONTEXTUALIZAÇÃO: As reduções da força do quadríceps e do pico de consumo de oxigênio (V.O2 em pacientes com doença pulmonar obstrutiva crônica (DPOC são estudadas em amostras relativamente pequenas e por curto período de tempo. Além disso, os resultados não são corrigidos por variáveis confundidoras, como conteúdo de massa magra, gênero e capacidade de difusão pulmonar. OBJETIVOS: Comparar a força muscular do quadríceps e o pico de V.O2 em mulheres e homens estratificados por idade e capacidade de difusão pulmonar e, ent

  1. 髌骨肌贴对股四头肌肌力及膝关节疼痛的影响%Effect of McConnell Taping on the quadriceps muscle strength and patellofemoral pain

    Institute of Scientific and Technical Information of China (English)

    罗盛飞; 曲由; 陈建; 李萍

    2014-01-01

    BACKGROUND:There is little attention focused on the effect of isokinetic testing about the variation of angular velocity on pain and muscle strength in the evaluation of curative effect of McConnel taping. OBJECTIVE: To evaluate the changes of quadriceps muscle strength and perceived pain levels in patients with patelofemoral pain syndrome before and after corrective McConnel taping in isokinetic testing. METHODS:A total of 34 patients with patelofemoral pain syndrome were evaluated in isokinetic testing for concentric contraction muscular strength, including the maximum torque, the total work, and the average work in 60 (°)/s and 180 (°)/s angular velocity, before and after the interventions of McConnel taping. The visual analogue scale scores were recorded. RESULTS AND CONCLUSION: The visual analogue scale scores were slightly decreased in angular velocity of 60 (°)/s after obturation when compared to before obturation (P > 0.05), while the scores were significantly decreased in angular velocity of 180 (°)/s (P 0.05), while significantly increased in 180 (°)/s angular velocity (P 0.05);在180(°)/s角速度下,髌骨肌贴应用后的分值较应用前显著下降(P <0.05)。②等速向心收缩肌力:在60(°)/s角速度下,髌骨肌贴应用后的峰力矩值、平均峰力矩、总功较应用前稍增加,但差异无显著性意义;在180(°)/s角速度下,髌骨肌贴应用后的峰力矩值、平均峰力矩、总功较应用前显著增加(P <0.05)。表明髌骨肌贴可显著改善髌股关节综合征患者低负荷关节运动时的疗效。

  2. High Intensity Neuromuscular Electrical Stimulation to Enhance Quadriceps Strength after Anterior Cruciate Ligament Reconstruction

    Institute of Scientific and Technical Information of China (English)

    Joseph A.Gallo; Christopher Proulx

    2010-01-01

    @@ Despite the implementation of accelerated ACL rehabilitation and improved surgical technique,persistent quadriceps weakness continues to be reported in the literature following ACL reconstruction.[1-4]The literature suggests,that the exclusive use of multijoint CKC exercises may not be selective enough in the recruitment of the quadriceps muscle.[5,6]Ernest et al demonstrated that hip and ankle extensors may compensate for a weak quadriceps during the lateral step-up exercise in subjects status post ACL reconstruction.[3

  3. Experimental evidence against the mitochondrial theory of aging - A study of isolated human skeletal muscle mitochondria

    DEFF Research Database (Denmark)

    Rasmussen, Ulla Fugmann; Krustrup, Peter; Kjær, Michael;

    2003-01-01

    age effects, ATP formation, BSA effects, collagen content, low temperature spectroscopy, oxygen uptakes, quadriceps muscle, respiration, specific enzyme activities......age effects, ATP formation, BSA effects, collagen content, low temperature spectroscopy, oxygen uptakes, quadriceps muscle, respiration, specific enzyme activities...

  4. Experimental evidence against the mitochondrial theory of aging - A study of isolated human skeletal muscle mitochondria

    DEFF Research Database (Denmark)

    Rasmussen, Ulla Fugmann; Krustrup, Peter; Kjær, Michael

    2003-01-01

    age effects, ATP formation, BSA effects, collagen content, low temperature spectroscopy, oxygen uptakes, quadriceps muscle, respiration, specific enzyme activities......age effects, ATP formation, BSA effects, collagen content, low temperature spectroscopy, oxygen uptakes, quadriceps muscle, respiration, specific enzyme activities...

  5. Sagittal patellar tilt and concomitant quadriceps hypotrophy after tibial nailing.

    Science.gov (United States)

    Aksahin, Ertugrul; Yilmaz, Serdar; Karasoy, Ismail; Duran, Semra; Yuksel, H Yalcin; Dogan, Ozgur; Yildirim, A Ozgur; Bicimoglu, Ali

    2016-09-01

    The aim of the study was to analyse the patellofemoral alignment in the sagittal plane following tibial fracture surgery with intramedullary nailing and its relationship to parapatellar muscle status. The patellofemoral MRI results of 27 patients (15 males and 12 females) treated with locked intramedullary nailing following tibia shaft fracture were reviewed. The mean age of the patients was 41.8 (±15) years. The patella-patellar tendon angle (P-PT) and the distance between the inferior patellar pole and the tibial tubercle (DP-TT) were evaluated for both the operated extremity and the contralateral normal side. MRI assessment of the infrapatellar fat pad, quadriceps, sartorius, gracilis, semi-membranosus muscles and biceps muscles was also carried out. The correlation between the changes in skeletal muscle mass, the volume of the infrapatellar fat pad and the alterations in the DP-TT distances and P-PT angles were analysed. The quadriceps muscle cross-sectional diameter had a mean of 157.2 mm(2) (115.6/319.5) in the operated extremity, and it was 193 mm(2) (77.6/282.2) in the non-operated normal side (p = 0.001). For the Gracilis muscle, the mean was 84.4 mm(2) (19.7/171) at the operated extremity and 75.7 mm(2) (26.9/238.2) on the normal side (p = 0.05). The cross-sectional areas of the semi-membranosus, sartorius and biceps muscles in the operated and non-operated extremity were not noticeably different (n.s). The P-PT angle was 153° (129.7/156.4) in the operated extremity and 145.7° (137.6/163.4) in the non-operated normal extremity (p hypotrophy negatively correlated (r = -0.4, p = 0.02) with the P-PT angle but positively correlated with the increase in gracilis muscle volume (r = 0.4, p = 0.03). This study revealed that patellofemoral joint kinematics in the operated extremity was diminished in the sagittal plane correlating with the quadriceps muscle volume loss and gracilis muscle hypertrophy. The modalities focused on both preventing

  6. Spontaneous bilateral quadriceps tendon rupture.

    Science.gov (United States)

    Vigneswaran, N; Lee, K; Yegappan, M

    2007-11-01

    Spontaneous bilateral quadriceps tendon ruptures are uncommon. We present a 30-year-old man with end-stage renal failure, who sustained this injury, and subsequently had surgical repair of both tendons on separate occasions. He has since regained full range of movement of both knees.

  7. EFFECT OF ISOMETRIC QUADRICEPS STRENGTHENING EXERCISE AT MULTIPLE ANGLES IN KNEE JOINT AMONG NORMAL ADULTS

    Directory of Open Access Journals (Sweden)

    JibiPaul

    2014-04-01

    Full Text Available Introduction: Strengthening exercises have been routinely used in persons with orthopaedic problems and athletes to increase force production or minimize muscle imbalance and joint injuries.Many studies have reported that isometric contractions can rapidly increases strength in quadriceps muscle. Objective: Objective of the study was to find out the effect of isometric strengthening exercise on strength of quadriceps at 45 and 90 degree of knee joint and also to compare the effect of strengthening exercise on strength of quadriceps at multiple angles of knee joint among control and experimental group. Methodology: This was a ccomparative experimental study with forty female healthy subjects from physiotherapy department of KPJ Healthcare University College, Malaysia. Convenient sampling method used to select the samples. The subjects were selected by inclusion criteria and randomly divided equally in to two with 20 subjects in each group. Isometric strengthening exercise and squatting exercise were given as intervention program for eight weeks respectively for experimental and control group. Pre and post data of quadriceps muscle strength measured were collected separately at 45 and 90 degree of knee joint using goniometry during resisted extension of knee in multi gym. Result: In experimental group Pre –Post statistical analysis found significant effect in increase of quadriceps strength at 45 and 90 degree with P<0.0001.****In control group quadriceps pre-post statistical analysis found no significant effect in increase of quadriceps strength at 45 and 90 degree with P<0.083NS and P<0.055 NS respectively. Comparative study between experimental and control groups for quadriceps strength at 90 degree of knee joint found significant effect in increase of quadriceps strength with P< 0.001.*** Comparative study between experimental and control groups for quadriceps strength at 45 degree of knee joint found significant effect in increase of

  8. Selective hypertrophy of the quadriceps musculature after 14 weeks of isokinetic and conventional resistance training.

    Science.gov (United States)

    Matta, Thiago Torres; Nascimento, Francisco Xavier; Trajano, Gabriel S; Simão, Roberto; Willardson, Jeffrey Michael; Oliveira, Liliam Fernandes

    2017-03-01

    One of the fundamental adaptations observed with resistance training (RT) is muscle hypertrophy. Conventional and isokinetic machines provide different forms of mechanical stress, and it is possible that these two training modes could promote differing degrees of hypertrophic adaptations. There is a lack of data comparing the selective hypertrophy of the quadriceps musculature after training with a conventional knee extension machine versus an isokinetic machine. The purpose of this study was to evaluate the selective hypertrophy of the quadriceps musculature and knee extension maximal isometric torque after 14 weeks of conventional versus isokinetic RT. Thirty-five men were assigned to three groups: control group and training groups (conventional and isokinetic) performed three sets of unilateral knee extensions per session with a progressive loading scheme twice a week. Prior to and following the intervention, maximal isometric knee extensor torque was measured using an isokinetic dynamometer, and muscle thickness (MT) of quadriceps femoris muscles was assessed via ultrasound. The results indicated non-uniform changes in MT between the muscles that comprise the quadriceps femoris group. For the conventional group, significantly greater increases in rectus femoris thickness were evident versus all other quadriceps muscles (14%). For the isokinetic group, increases in RF thickness (11%) were significantly greater in comparison with the vastus intermedius only. Although the muscle thickness did not increase for all the quadriceps femoris muscles, the relative rectus femoris adaptation suggested a selective hypertrophy favouring this portion. © 2015 Scandinavian Society of Clinical Physiology and Nuclear Medicine. Published by John Wiley & Sons Ltd.

  9. Quadriceps bulk and strength and effect of its training in patients with moderate to severe chronic obstructive pulmonary disease

    Directory of Open Access Journals (Sweden)

    Nasr Affara

    2013-01-01

    Conclusion: We have collected evidence indicating that both bulk and strength of quadriceps muscles in particular were reduced in patients with COPD compared with normal controls and these changes can be improved with progressive training without change in pulmonary functions.

  10. Handgrip strength, quadriceps muscle power, and optimal shortening velocity roles in maintaining functional abilities in older adults living in a long-term care home: a 1-year follow-up study

    Directory of Open Access Journals (Sweden)

    Kozicka I

    2016-05-01

    Full Text Available Izabela Kozicka, Tomasz Kostka Department of Geriatrics, Medical University of Lodz, Lodz, Poland Purpose: To assess the relative role of handgrip strength (HGS, quadriceps muscle power (Pmax, and optimal shortening velocity (υopt in maintaining functional abilities (FAs in older adults living in a long-term care home over a 1-year follow-up. Subjects and methods: Forty-one inactive older institutionalized adults aged 69.8±9.0 years participated in this study. HGS, Pmax, υopt, cognitive function using the Mini-Mental State Examination, depressive symptoms using the Geriatric Depression Scale, nutritional status using the Mini Nutritional Assessment (MNA, and physical activity (PA using the Seven-Day Physical Activity Recall Questionnaire were assessed at baseline and at 1-year follow-up. FAs were assessed with activities of daily living (ADL, instrumental ADL, and Timed Up & Go test. Results: Both at baseline and at follow-up, FAs were related to age, HGS, Pmax/kg, υopt, MNA, and PA. These associations were generally similar in both sexes. As revealed in multiple regression analysis, υopt was the strongest predictor of FA, followed by Pmax/kg, PA, and MNA. FA deteriorated after 1 year as measured by ADL and Timed Up & Go test. Pmax and υopt, but not HGS, also decreased significantly after 1 year. Nevertheless, 1-year changes in FAs were not related to changes in HGS, Pmax, υopt, or PA. Conclusion: The 1-year period of physical inactivity among older institutionalized adults was found to have a negative effect on their FAs, Pmax, and υopt. The present study demonstrates that Pmax and, especially, υopt correlated with FAs of older adults more than HGS, both at baseline and at follow-up. Despite this, 1-year natural fluctuations of PA, Pmax, and υopt are not significant enough to influence FAs in inactive institutionalized older adults. Keywords: aging, handgrip strength, institutionalization, functional status, physical activity

  11. Accuracy of predicting maximal quadriceps force from submaximal effort contractions after anterior cruciate ligament injury.

    Science.gov (United States)

    Farquhar, Sara J; Chmielewski, Terese L; Snyder-Mackler, Lynn

    2005-10-01

    Weakness and failure of voluntary activation of the quadriceps femoris muscles often occur after anterior cruciate ligament (ACL) rupture. Side-to-side strength comparisons are used as a measure of progress, and are inaccurate if the quadriceps has activation failure. Burst superimposition testing is commonly used to assess quadriceps strength and activation during a maximal volitional isometric contraction (MVIC), using the central activation ratio (CAR) calculation. A recently developed mathematical model predicts the MVIC from submaximal efforts. The purpose of this study was to compare the CAR calculation to the mathematical model. We hypothesized that the model would be a more accurate predictor of strength than the CAR calculation when voluntary activation failure is present. Data from the involved and uninvolved quadriceps muscles of 100 consecutive subjects with complete, isolated ACL rupture were retrospectively evaluated. Subjects who required multiple trials to produce an MVIC with full activation (true MVIC) were used to compare the CAR calculation, the mathematical model, and this true MVIC. Subjects unable to produce a true MVIC with multiple trials were used to compare the mathematical model to the CAR calculation. Results demonstrate that both methods reliably and accurately estimate the quadriceps weakness associated with ACL rupture. We recommend use of the CAR calculation to provide estimations of true quadriceps strength to facilitate clinical decisions about progress in rehabilitation after ACL rupture.

  12. Use of adjunctive prednisolone in the management of a cat with bilateral quadriceps contracture following trauma

    Directory of Open Access Journals (Sweden)

    Penelope LC Tisdall

    2017-03-01

    Full Text Available Case summary A 6-month-old cat was successfully treated for bilateral quadriceps contracture. Conventional treatments including surgery, dynamic flexion apparatus and physical therapy along with analgesics and non-steroidal anti-inflammatory drugs resulted in temporary clinical improvement that was relapsing. The initiation of supplementary corticosteroid treatment with prednisolone coincided with an immediate and sustained clinical improvement and long-term resolution. Relevance and novel information Successful treatment of bilateral quadriceps contracture has not previously been reported in a cat. Quadriceps contracture remains a challenging condition to treat with some cases unresponsive to therapy. Systemic prednisolone treatment appeared to be of benefit in the management of this case and may have a role in some cats where muscle contracture appears relapsing in nature. Further prospective investigations in cats with muscle contracture, including muscle biopsies of affected cats, are warranted.

  13. Outcome of quadriceps tendon repair.

    Science.gov (United States)

    Puranik, Gururaj S; Faraj, Adnan

    2006-04-01

    Complete rupture of the quadriceps tendon is a well-described injury. There is a scarcity of literature relating to the outcome of patients with this injury after surgery. We undertook a retrospective analysis of patients who had surgical repair of their quadriceps tendon at our institution over a 13-year period, totalling 21 patients. Males were more commonly affected, with a male/female ratio of 4:1. The peak incidence was in the sixth decade of life. Assessment consisted of the completion of a functional knee questionnaire and a clinical examination. Symptomatic outcome following surgical repair was good with a mean symptom score generated of 19.16 out of a maximum of 25 using the Rougraff et al scoring system. Most of the patients returned to their pre-injury level of activity. Five degrees deficit and extension lag was present in three patients; these patients had the quadriceps repaired using transosseous sutures. Patients who had direct repair of the tendon using the Bunnell technique had lower Rougraff scores than the rest.

  14. Functional results after surgical repair of quadriceps tendon rupture.

    Science.gov (United States)

    De Baere, T; Geulette, B; Manche, E; Barras, L

    2002-04-01

    We present the long-term results of surgical repair of a traumatic rupture of the quadriceps tendon in a group of 24 patients with a mean age of 58 years. There were 21 male and 3 female patients. Fifteen patients were seen for clinical control after a mean follow-up of 75 months and they all presented with some quadriceps muscle atrophy. Twelve patients had normal knee mobility, three had a flexion deformity of 10 degrees and two had less than 120 degrees of knee flexion. Active knee extension was normal in all patients. Three patients experienced some decrease in stability of their knee joint. Subjectively all patients were satisfied with the result. Nine patients underwent a Cybex-test for evaluation of the isokinetic force of knee flexion and extension, with a comparison between the injured and the uninjured side. For concentric force there was a mean deficit at low speed of 36.1% for the quadriceps muscle; at high speed it was 28.2%. For the knee flexors, the deficits were 30.7% and 27.2% respectively. Regarding eccentric force, the mean deficit for knee extensors was 13.8% and 0.25% respectively and for knee flexors 6.5% and 5.5% respectively.

  15. 下肢肌肉链训练与股四头肌训练治疗膝骨关节炎的疗效对比研究%Comparative Studies on Lower Extremity Muscle Chains and Quadriceps Femoris Training for the Treatment of Knee Osteoarthritis

    Institute of Scientific and Technical Information of China (English)

    刘晓林; 林坚; 黄雄昂; 蒋天武

    2013-01-01

    Objective To evaluate clinical effects of the lower extremity muscle chains training and quadriceps femoris training on the treatment of knee osteoarthritis ( KOA ) . Methods From March 2011 to Septemper 2012, 70 patients with knee osteoarthritis were randomly and evenly divided into control group and research group according to visiting sequence. Patients in the control group were given routine quadriceps femoris training, and the research group were given lower extremity muscle chains training based on muscle chains theory. Before and after eight weeks treatment, the clinical effect was evaluated using Lysholm score and JOA score as index. Results Comparisons of Lysholm score and JOA score between two groups before treatment were not significantly different ( P > 0. 05 ); After treatment, the Lysholm score and JOA score in research group were significantly higher than those in control group ( P < 0. 05 ) . Conclusion The effect of lower extremity muscle chains training is better than the quadriceps femoris training in improving joint function for the treatment of KOA.%目的 探讨下肢肌肉链训练与股四头肌训练在膝骨关节炎(KOA)康复治疗中的临床疗效.方法 选取2011年3月-2012年9月我院收治的70例KOA患者,按就诊先后顺序随机分为对照组35例和研究组35例.对照组采用传统股四头肌训练,研究组采用基于肌肉链理论的下肢肌肉链训练,治疗前和治疗8周后使用Lysholm评分、治疗效果判定标准(JOA)评分对临床疗效进行.结果 研究组治疗前Lysholm评分、JOA评分与对照组比较,差异均无统计学意义(P>0.05);研究组治疗后Lysholm评分、JOA评分较对照组明显升高,差异均有统计学意义(P<0.05).结论 肌肉链训练疗效优于单纯股四头肌训练,对KOA功能恢复具有明显作用.

  16. Quadriceps strength assessed by magnetic stimulation of femoral nerve in patients with chronic obstructive pulmonary disease

    Institute of Scientific and Technical Information of China (English)

    JU Chun-rong; CHEN Rong-chang

    2011-01-01

    Background Skeletal muscle dysfunction is one of important systemic manifestations of chronic obstructive pulmonary disease (COPD) and is associated with mortality in patients with COPD, thus quantifying its strength is of great clinical interest and of particular value. Quadriceps maximal volitional contraction (MVC) is often used for the routine measurements of this muscle's strength; while twitch tension (TwQ) evoked by magnetic stimulation of the femoral nerve has been employed for measurement of quadriceps strength non-volitionally. We aimed to investigate the prevalence and severity of skeletal muscle dysfunction in COPD patients by measurement of quadriceps strength with volitional and non-volitional techniques, and to probe into some methodological issues. Methods We recruited 71 COPD patients and 60 control subjects. Quadriceps strength was measured with both maximality of TwQ and MVC force. The reproducibility for TwQ and MVC was investigated using within-occasion variability from three repeated maneuvers. Results Maximal TwQ was achieved in 121 participants at a mean of 90% of the stimulator's maximum output. The mean maxmality of TwQ was decrease by about 44%-47% in COPD patients as compared with controls (P<0.05), so was MVC. There was a significant correlation between quadriceps TwQ and MVC, and the mean ratio of TwQ/MVC was 0.29 in controls and 0.33 in patients. The coefficient of variation showed that TwQ yielded lower within-occasion variability than MVC in both groups. Conclusions Quadriceps strength is commonly and substantially impaired in patients with COPD, in terms of MVC as well as TwQ. The magnetic stimulation of the femoral nerve presents a higher reproducibility and is a better technique for measurement of quadriceps strength for the general population, especially for those who are too unwell to perform a full MVC; while it may not be applied to subjects who are over-weighted.

  17. An examination of possible quadriceps force at the time of anterior cruciate ligament injury during landing: A simulation study.

    Science.gov (United States)

    Domire, Zachary J; Boros, Rhonda L; Hashemi, Javad

    2011-05-17

    Anterior cruciate ligament (ACL) rupture is a common and traumatic injury. Although, identifying the mechanism of ACL injury has received considerable research attention, there are still many unanswered questions. One proposed mechanism asserts that the ACL is injured due to an aggressive quadriceps muscle contraction. However, recently it has been questioned if the magnitude of quadriceps force needed to tear the ACL is physiologically realistic under the conditions where injury occurs during landing (e.g. near full knee extension and within 50ms after impact). To answer this question, a simple simulation model was developed to examine the upper bounds of quadriceps force that can be developed under these conditions. The model included force-length, and force-velocity properties as well as activation dynamics. Model parameters were chosen to provide a high estimate for possible quadriceps force in a young healthy man. The effects of varying quadriceps pre-activation levels were also examined. When using realistic pre-activation levels, the simulated quadriceps force was less than half of what has been shown to cause ACL injury. Even when using maximum pre-activation, the quadriceps force still did not reach close to the level shown to cause injury. Therefore, we conclude that quadriceps force alone seems to be an unlikely mechanism for ACL injury.

  18. Simultaneous and spontaneous bilateral quadriceps tendons rupture.

    Science.gov (United States)

    Celik, Evrim Coşkun; Ozbaydar, Mehmet; Ofluoglu, Demet; Demircay, Emre

    2012-07-01

    Simultaneous and spontaneous bilateral quadriceps tendon rupture is an uncommon injury that is usually seen in association with multiple medical conditions and some medications. We report a case of simultaneous and spontaneous bilateral quadriceps tendon rupture that may be related to the long-term use of a statin.

  19. Combination of eccentric exercise and neuromuscular electrical stimulation to improve quadriceps function post-ACL reconstruction.

    Science.gov (United States)

    Lepley, Lindsey K; Wojtys, Edward M; Palmieri-Smith, Riann M

    2015-06-01

    Neuromuscular electrical stimulation (NMES) has been shown to reduce quadriceps activation failure (QAF), and eccentric exercise has been shown to lessen muscle atrophy post-ACL reconstruction. Given that these are two critical components of quadriceps strength, intervention combining these therapies may be effective at reinstituting quadriceps function post-reconstruction. Thus, the aim of this study was to evaluate the effectiveness of a combined NMES and eccentric exercise intervention to improve the recovery of quadriceps activation and strength post-reconstruction. Thirty-six individuals post-injury were placed into four treatment groups (N&E, NMES and eccentrics; E-only, eccentrics only; N-only, NMES-only; and STND, standard of care) and ten healthy controls participated. N&E and N-only received the NMES protocol 2× per week for the first 6 weeks post-reconstruction. N&E and E-only received the eccentric exercise protocol 2× per week beginning 6 weeks post-reconstruction. Quadriceps activation was assessed via the superimposed burst technique and quantified via the central activation ratio. Quadriceps strength was assessed via maximal voluntary isomeric contractions (Nm/kg). Data was gathered on three occasions: pre-operative, 12-weeks-post-surgery and at return-to-play. No differences in pre-operative measures existed (P>0.05). E-only recovered quadriceps activation better than N-only or STND (P0.05). Eccentric exercise was capable of restoring levels of quadriceps activation and strength that were similar to those of healthy adults and better than NMES alone. Level 3, Parallel longitudinal study. Copyright © 2014 Elsevier B.V. All rights reserved.

  20. Quadriceps tendon rupture - treatment results

    Directory of Open Access Journals (Sweden)

    Popov Iva

    2013-01-01

    Full Text Available Introduction. Quadriceps tendon rupture is a rare but rather serious injury. If this injury is not promptly recognized and early operated, it may lead to disability. This research was aimed at pointing out the results and complications of the quadriceps tendon rupture surgical treatment. Material and Methods. This retrospective multicentric study was conducted in a group of 29 patients (mostly elderly men. Lysholm knee scoring scale was used to evaluate the surgical results. The post-operative results were compared in relation to the type of tendon rupture reconstructions (acute or chronic, various surgical techniques, type of injuries (unilateral or bilateral as well as the presence or absence of comorbid risk factors in the patients. Results. The average value of a Lysholm score was 87.6. Excellent and satisfactory Lysholm score results dominated in our sample of patients. Better post-operative results were recorded in the group of patients without risk factors, in case of a bilateral injury, and in case of an acute injury. The best result was obtained after performing the reconstruction using anchors, and the worst result came after using Codivilla technique. Discussion and Conclusion. Early diagnosis and surgical treatment are an absolute imperative in management of this injury. We have not proven that a certain surgical technique has an advantage over the others. A comorbid risk factor is related to a lower Lysholm score. Despite a few cases of complications, we can conclude that the surgical treatment yields satisfactory results.

  1. Quadriceps and patellar tendon ruptures.

    Science.gov (United States)

    Lee, Dennis; Stinner, Daniel; Mir, Hassan

    2013-10-01

    The diagnosis of quadriceps and patellar tendon ruptures requires a high index of suspicion and thorough history-taking to assess for medical comorbidities that may predispose patients to tendon degeneration. Radiographic assessment with plain films supplemented by ultrasound and magnetic resonance imaging when the work-up is equivocal further aids diagnosis; however, advanced imaging is often unnecessary in patients with functional extensor mechanism deficits. Acute repair is preferred, and transpatellar bone tunnels serve as the primary form of fixation when the tendon rupture occurs at the patellar insertion, with or without augmentation depending on surgeon preference. Chronic tears and disruptions following total knee arthroplasty are special cases requiring reconstructions with allograft, synthetic mesh, or autograft. Rehabilitation protocols generally allow immediate weight-bearing with the knee locked in extension and crutch support. Limited arc motion is started early with active flexion and passive extension and then advanced progressively, followed by full active range of motion and strengthening. Complications are few but include quadriceps atrophy, knee stiffness, and rerupture. Outcomes are excellent if repair is done acutely, with poorer outcomes associated with delayed repair.

  2. Quadriceps Strength, Quadriceps Power, and Gait Speed in Older U.S. Adults with Diabetes: Results from the National Health and Nutrition Examination Survey (NHANES), 1999–2002

    Science.gov (United States)

    Kalyani, Rita Rastogi; Tra, Yolande; Yeh, Hsin-Chieh; Egan, Josephine M.; Ferrucci, Luigi; Brancati, Frederick L.

    2013-01-01

    strength and quadriceps power that is related to the presence of comorbidities. Persons with diabetes also walk slower. Future studies should investigate the relationship of hyperglycemia with subsequent declines in leg muscle function. PMID:23617584

  3. Effects of preoperative neuromuscular electrical stimulation on quadriceps strength and functional recovery in total knee arthroplasty. A pilot study.

    LENUS (Irish Health Repository)

    Walls, Raymond J

    2010-01-01

    Supervised preoperative muscle strengthening programmes (prehabilitation) can improve recovery after total joint arthroplasty but are considered resource intensive. Neuromuscular electrical stimulation (NMES) has been shown to improve quadriceps femoris muscle (QFM) strength and clinical function in subjects with knee osteoarthritis (OA) however it has not been previously investigated as a prehabilitation modality.

  4. Effect of Adductor Canal Block Versus Femoral Nerve Block on Quadriceps Strength, Mobilization, and Pain After Total Knee Arthroplasty

    DEFF Research Database (Denmark)

    Grevstad, Jens Ulrik; Mathiesen, Ole; Valentiner, Laura Risted Staun;

    2015-01-01

    BACKGROUND AND OBJECTIVES: Total knee arthroplasty (TKA) is often associated with severe pain. Different regional anesthetic techniques exist, all with varying degrees of motor blockade. We hypothesized that pain relief provided by the adductor canal block (ACB) could increase functional muscle....... CONCLUSION: Adductor canal block provides a clinically relevant and statistically significant increase in quadriceps muscle strength for patients in severe pain after TKA....

  5. Histologic analysis of ruptured quadriceps tendons.

    Science.gov (United States)

    Trobisch, Per David; Bauman, Matthias; Weise, Kuno; Stuby, Fabian; Hak, David J

    2010-01-01

    Quadriceps tendon ruptures are uncommon injuries. Degenerative changes in the tendon are felt to be an important precondition for rupture. We retrospectively reviewed 45 quadriceps tendon ruptures in 42 patients. Quadriceps tendon ruptures occurred most often in the sixth and seventh decade of life. Men were affected six times as often as women. A tissue sample from the rupture-zone was obtained in 22 cases and histologic analysis was performed. Degenerative changes were present in only 14 (64%) of the 22 samples. We observed an increasing ratio of degenerative to nondegenerative tendons with increasing patient age. Our data suggests that quadriceps tendon rupture, especially in younger patients, can occur in the absence of pathologic tendon degeneration.

  6. Quadriceps and hamstrings prelanding myoelectric activity during landing from different heights among male and female athletes.

    Science.gov (United States)

    de Britto, Morgana Alves; Carpes, Felipe P; Koutras, Georgios; Pappas, Evangelos

    2014-08-01

    ACL tear is a major concern among athletes, coaches and sports scientists. More than taking the athlete away from training and competition, ACL tear is a risk factor for early-onset of knee osteoarthritis, and, therefore addressing strategies to avoid such injury is pertinent not only for competitive athletes, but for all physically active subjects. Imbalances in the prelanding myoelectric activity of the hamstrings and quadriceps muscles have been linked to ACL injuries. We investigated the effect of landing from different heights on prelanding myoelectric activity of the hamstrings and quadriceps muscles in recreational athletes. Thirty recreational athletes (15 male and 15 female) performed three bilateral drop jumps from two different heights; 20cm and 40cm while myoelectric activity of the vastus medialis, rectus femoris, biceps femoris and medial hamstrings were collected. When increasing the height of drop landing tasks prelanding normalized myoelectric activity of the quadriceps was increased by 15-20% but no significant changes were found for the hamstrings. Female athletes exhibited higher activity of the medial hamstrings compared to their male counterparts. We concluded that increasing the height of drop landing tasks is associated with increased myoelectric activity of the quadriceps but not the hamstrings in recreational athletes. These differences in muscle activity may be related to increased risk for ACL injury when the height is increased. Female athletes demonstrated higher recruitment of the medial hamstrings. Copyright © 2014 Elsevier Ltd. All rights reserved.

  7. 按摩增强琥珀酸脱氢酶和钾—钠ATP酶活性促进兔股四头肌的损伤修复%Massage promotes repairing of injured quadriceps femoris muscle of rabbit through enhancing activity of SDH and K +-Na + -ATPase

    Institute of Scientific and Technical Information of China (English)

    侯懿烜; 郑元义; 张萍; 刘祖丽; 郜婕; 唐成林

    2011-01-01

    目的 研究按摩对骨骼肌损伤修复关键酶琥珀酸脱氢酶(SDH)、钾—钠ATP酶(K+-Na+ -ATPase)活性的影响.方法将30只雄性新西兰大白兔分为健康对照组(3只)、自然恢复组(15只)和按摩组(12只).根据损伤造模后观察时间的不同,自然恢复组分为3个时相点,即自然恢复7d组(3只)、按摩7d对照组(自然恢复14 d,6只)和按摩14 d对照组(自然恢复21 d,6只),按摩组分为按摩7、14 d组(各6只).重物打击法制作兔股四头肌急性损伤模型.HE、超声影像技术检测组织病理变化,酶组化法检测SDH酶、K+-Na+ -ATPase活性.结果组织病理检测显示按摩对照组受损肌组织肿胀、萎缩退变,按摩治疗后修复或新生肌纤维明显增多.超声影像研究显示按摩对照组受损肌纤维纹理消失、回波呈弥漫性非均匀增强,按摩组回波呈弥漫均一性增强、边缘清晰.SDH和K+-Na+ -ATPase活性研究结果进一步显示:按摩7d组(0.003 3±0.0002)vs(0.002 2±0.0002)和14 d组(0.003 9±0.000 2)vs(0.003 2±0.000 1)较对应的按摩对照组SDH活性明显增加(P<0.01),SDH深染的Ⅰ型肌纤维数量百分比高于对应的按摩对照组[7d组:(38.6±2.6)%vs(25.1±1.7)%,P<0.01;14 d组:(56.2±4.5)%vs(30.3±2.1)%,P<0.01];ATPase活性分别在按摩7d组和14 d组比对应的按摩对照组升高约47%和72% (P<0.01).结论按摩可能通过提高受损肌组织有氧代谢相关酶类活性,促进受损肌组织的修复.%Objective To investigate the role and its mechanism of massage on the recovery of damaged skeletal muscle. Methods A total of 24 adult male New Zealand rabbits were randomly divided into 3 groups, normal control (n =3) , self-repairing group (n = 15, further divided into 7, 14 and 21 d time points) , and massage group (re = 12, further divided into 7 and 14 d time points). The quadriceps femoris injured models were established by hammering the muscle with self-made lead hitter. Massage was

  8. Patellar hypomobility and the flexibility of the iliotibial band and the femoral quadriceps.

    Science.gov (United States)

    Getka, Aleksandra

    2005-12-30

    Background. The aim of our study was to determine whether or not the flexibility of the iliotibial band and femoral quadriceps have an impact on patellar hypomobility, due to their connections with the patellar stabilizers. Material and methods. We examined 62 patients (44 females, 18 males) with a median age of 15 years (range 9-19). All these patients had patellofemoral dysfunction in the tested knees (101). The medial and distal glide of the patella were tested with a manual test according to Kaltenborn's scale. Ober's test was performed to test the tightness of the iliotibial band. The flexibility of the quadriceps femoris was tested while the patient was lying prone with the tested leg on the couch and the other beside it. Results. Statistical analysis based on the c2 test (P=0.05) found no dependence between the flexibility parameters of the iliotibial band or the femoral quadriceps and the parameters of patellar hypomobility. Of the tested joints, 37.6% showed hypomobile patella and positive Ober's test, while 34.7% had hypomobile patella and a positive test for femoral quadriceps flexibility. Conclusions. The flexibility of the iliotibial band and femoral quadriceps has no direct influence on passive patellar hypomobility, but can affect the biomechanics of the patellofemoral joint and the location of the point of contact on articular surfaces during dynamic knee work. The flexibility of these muscles should be a diagnostic factor in patients with patellofemoral dysfunction.

  9. GNE mutations in an American family with quadriceps-sparing IBM and lack of mutations in s-IBM.

    Science.gov (United States)

    Vasconcelos, Olavo M; Raju, Raghavan; Dalakas, Marinos C

    2002-12-10

    Analysis for GNE mutations was performed in an American, non-Iranian Jewish, family with quadriceps-sparing inclusion body myopathy (QS-IBM) and in 11 patients with sporadic IBM (s-IBM). Two novel nonallosteric site missense mutations were found in the QS-IBM kinship. No mutations were identified in s-IBM patients. After 8 years of follow-up and severe disease progression, the quadriceps muscle in the QS-IBM patient remains strong despite subclinical involvement documented with repeat MRI and muscle biopsy.

  10. Functional and morphological changes in the quadriceps muscle induced by eccentric training after ACL reconstruction Alterações funcionais e morfológicas do quadríceps induzidas pelo treinamento excêntrico após reconstrução do LCA

    Directory of Open Access Journals (Sweden)

    Jamilson S. Brasileiro

    2011-08-01

    Full Text Available OBJECTIVES: The purpose of this study was to investigate the contributions of functional and morphological factors in the recovery of the quadriceps muscle after anterior cruciate ligament (ACL reconstruction. METHODS: Nine subjects (31.3±5.8 years underwent eccentric exercise sessions twice a week for 12 weeks. Quadriceps muscle function was evaluated using an isokinetic dynamometer (isometric and eccentric peak torque and electromyography (RMS. Morphological changes were measured using magnetic resonance imaging. RESULTS: The initial evaluation showed a significant deficit in knee extensor torque in the involved limb and significant muscle atrophy along the length of the quadriceps. EMG activity was lower in all tested situations. Eccentric training significantly increased isokinetic torque (from 199±51 to 240±63, pOBJETIVOS: O propósito deste estudo foi avaliar as contribuições dos fatores funcionais e morfológicos na recuperação da força muscular do quadríceps femoral após reconstrução do Ligamento Cruzado Anterior (LCA. MÉTODOS: Nove indivíduos (31,3±5,8 anos foram treinados por meio de contrações excêntricas máximas, duas vezes por semana, durante 12 semanas. A função do quadríceps foi avaliada pela dinamometria isocinética (pico de torque isométrico e excêntrico e pela eletromiografia (EMG. As alterações morfológicas foram mensuradas por meio de ressonância magnética (RNM. Na avaliação inicial, observou-se significativo déficit no torque extensor do joelho do membro acometido, com hipotrofia muscular de todo o quadríceps e redução na atividade EMG, quando comparado ao membro não-acometido. RESULTADOS: O treinamento excêntrico produziu aumento no torque excêntrico a 30º/s (de 199±51 Nm para 240±63 Nm, p<0,05 e no volume muscular, sendo que maiores hipertrofias ocorreram na região proximal da coxa (de 169±27 para 189±25,8 cm², p<0,01. A atividade EMG do Vasto Medial (VM aumentou nas primeiras

  11. [Lewis-Sumner syndrome presenting unilateral quadriceps amyotrophy as an initial symptom].

    Science.gov (United States)

    Fujiyama, J; Aita, T; Itoh, K; Hamano, T; Kumano, T; Kinomoto, K; Fujii, A; Yasokawa, T; Kuriyama, M

    2000-11-01

    We report a 55-year-old man with a chief complaint of wasting and weakness of the left quadriceps muscle. At age 54, he noticed difficulty in running and weakness in the left thigh, which gradually progressed. On the first admission to our hospital, based on the nerve conduction studies (NCS), the muscle biopsy findings showing neurologenic changes, and no abnormality of spinal MRI, we diagnosed as unilateral quadriceps amyotrophy, which resulted from an atypical form of spinal progressive muscular atrophy. One year later, he showed the bilateral hand weakness, conduction blocks on the right median and ulnar nerves by NCS, and the presence of serum anti-GM 1 antibody. From these findings, Lewis-Sumner syndrome was diagnosed. The therapy of high-dose intravenous immunoglobulin moderately improved his symptoms. The clinical symptoms of quadriceps amyotrophy is produced by various disorders including spinal progressive muscular atrophy, spinal extradural arachnoid cyst, rimmed vacuole myopathy, Becker dystrophy, limb-girdle dystrophy, and focal myositis. However, there have been no reports of a case of Lewis-Sumner syndrome. It is important to consider Lewis-Sumner syndrome in the differential diagnosis of quadriceps amyotrophy.

  12. Arthroscopic Quadriceps Tendon Repair: Two Case Reports

    Directory of Open Access Journals (Sweden)

    Hidetomo Saito

    2015-01-01

    Full Text Available Recently, although some studies of open repair of the tendon of the quadriceps femoris have been published, there have been no reports in the literature on primary arthroscopic repair. In our present study, we present two cases of quadriceps tendon injury arthroscopically repaired with excellent results. Case 1 involved a 68-year-old man who was injured while shifting his weight to prevent a fall. MRI showed complete rupture at the insertion of the patella of the quadriceps tendon. The rupture was arthroscopically repaired using both suture anchor and pull-out suture fixation methods via bone tunnels (hereafter, pull-out fixation. Two years after surgery, retearing was not observed on MRI and both Japan Orthopedic Association (JOA Knee and Lysholm scores had recovered to 100. Case 2 involved a 50-year-old man who was also injured when shifting his weight to prevent a fall. MRI showed incomplete superficial rupture at the insertion of the patella of the quadriceps tendon. The rupture was arthroscopically repaired using pull-out fixation of six strand sutures. One year after surgery, MRI revealed a healed tendon and his JOA and Lysholm scores were 95 and 100, respectively. Thus, arthroscopic repair may be a useful surgical method for repairing quadriceps tendon injury.

  13. Arthroscopic quadriceps tendon repair: two case reports.

    Science.gov (United States)

    Saito, Hidetomo; Shimada, Yoichi; Yamamura, Toshiaki; Yamada, Shin; Sato, Takahiro; Nozaka, Koji; Kijima, Hiroaki; Saito, Kimio

    2015-01-01

    Recently, although some studies of open repair of the tendon of the quadriceps femoris have been published, there have been no reports in the literature on primary arthroscopic repair. In our present study, we present two cases of quadriceps tendon injury arthroscopically repaired with excellent results. Case 1 involved a 68-year-old man who was injured while shifting his weight to prevent a fall. MRI showed complete rupture at the insertion of the patella of the quadriceps tendon. The rupture was arthroscopically repaired using both suture anchor and pull-out suture fixation methods via bone tunnels (hereafter, pull-out fixation). Two years after surgery, retearing was not observed on MRI and both Japan Orthopedic Association (JOA) Knee and Lysholm scores had recovered to 100. Case 2 involved a 50-year-old man who was also injured when shifting his weight to prevent a fall. MRI showed incomplete superficial rupture at the insertion of the patella of the quadriceps tendon. The rupture was arthroscopically repaired using pull-out fixation of six strand sutures. One year after surgery, MRI revealed a healed tendon and his JOA and Lysholm scores were 95 and 100, respectively. Thus, arthroscopic repair may be a useful surgical method for repairing quadriceps tendon injury.

  14. Bilateral rectus femoris intramuscular haematoma following simultaneous quadriceps strain in an athlete: a case report

    Directory of Open Access Journals (Sweden)

    Papathanasiou Efthymia

    2010-02-01

    Full Text Available Abstract Introduction Bilateral rectus femoris haematoma following a simultaneous strain of the quadriceps muscles is a very rare condition. Case presentation We report the case of a 21-year-old Greek Caucasian female rowing athlete who was injured on both thighs. She complained of pain and inability to walk. Physical examination revealed tenderness over the thighs and restriction of knee movement. The result of a roentgenogram was normal, and there was no evidence of fracture or patella displacement. Magnetic resonance imaging revealed haematoma formation in both the rectus femoris muscles. The diameters of the left and right haematomas within the muscles were 6 cm and 5 cm, respectively. Therapeutic approaches included compression bandages, ice application, rest, elevation, and administration of muscle relaxant drugs. Active stretching and isometric exercises were performed after three days. The patient was able to walk using crutches two days after the initiation of treatment. On the seventh day, she had regained her full ability to walk without crutches. Non-steroidal anti-inflammatory drugs were administered on the fifth day and continued for one week. Six weeks later, she had pain-free function and the result of magnetic resonance imaging was normal. She was able to resume her training programme and two weeks later, she returned to her previous sport activities and competitions. Conclusion There are references in the literature regarding the occurrence of unilateral quadriceps haematomas following strain and bilateral quadriceps tendon rupture in athletes. Simultaneous bilateral rectus femoris haematomas after a muscle strain is a rare condition. It must be diagnosed early. The three phases of treatment are rest, knee mobilization, and restoration of quadriceps function.

  15. Atraumatic quadriceps tendon tear associated with calcific tendonitis.

    Science.gov (United States)

    Abram, Simon G F; Sharma, Akash D; Arvind, Chinnakonda

    2012-11-27

    Calcific tendonitis of the quadriceps tendon is an uncommon condition. We present the first case of a quadriceps tendon tear associated with calcific tendonitis. In this case, the patient presented with symptoms mimicking a rupture of the quadriceps tendon. This case illustrates that although calcific tendonitis of the quadriceps is a rare condition it is not benign and should be considered when investigating acute symptoms associated with the extensor mechanism of the knee.

  16. Effect of transcutaneous electrical muscle stimulation on muscle volume in patients with septic shock

    DEFF Research Database (Denmark)

    Poulsen, Jesper Brøndum; Møller, Kirsten; Jensen, Claus V

    2011-01-01

    Objective: Intensive care unit admission is associated with muscle wasting and impaired physical function. We investigated the effect of early transcutaneous electrical muscle stimulation on quadriceps muscle volume in patients with septic shock. Design: Randomized interventional study using...... randomization of the quadriceps muscles, transcutaneous electrical muscle stimulation was applied on the intervention side for 7 consecutive days and for 60 mins per day. All patients underwent computed tomographic scans of both thighs immediately before and after the 7-day treatment period. The quadriceps...... (interquartile range, 20–29), respectively. During the 7-day study period, the volume of the quadriceps muscle on the control thigh decreased by 16% (4–21%, p = .03) corresponding to a rate of 2.3% per day. The volume of the stimulated muscle decreased by 20% (3–25%, p = .04) corresponding to a rate of 2.9% per...

  17. Quadriceps tendon rupture through a superolateral bipartite patella.

    Science.gov (United States)

    Woods, G William; O'Connor, Daniel P; Elkousy, Hussein A

    2007-10-01

    We report a case of a quadriceps tendon rupture through a bipartite patella. Although quadriceps tendon ruptures and patella fractures are common, rupture through a bipartite patella fragment is rare. This case was managed similar to a quadriceps rupture with an excellent result.

  18. Experimental knee joint pain during strength training and muscle strength gain in healthy subjects

    DEFF Research Database (Denmark)

    Sørensen, T J; Langberg, Henning; Hodges, P W

    2012-01-01

    Knee joint pain and reduced quadriceps strength are cardinal symptoms in many knee pathologies. In people with painful knee pathologies, quadriceps exercise reduces pain, improves physical function, and increases muscle strength. A general assumption is that pain compromises muscle function...... and thus may prevent effective rehabilitation. This study evaluated the effects of experimental knee joint pain during quadriceps strength training on muscle strength gain in healthy individuals....

  19. Muscle slowness in a family with nemaline myopathy.

    NARCIS (Netherlands)

    Gommans, I.M.P.; Gerrits, K.H.; Haan, A. de; Engelen, B.G.M. van

    2006-01-01

    All patients of a large family with nemaline myopathy complained of slowness in movement. We confirmed this clinical complaint physiologically by showing lower contractile speed in quadriceps muscle. Electrically evoked contractions of the quadriceps muscle elicited a lower rate of relaxation and a

  20. Facilitation of quadriceps activation is impaired following eccentric exercise.

    Science.gov (United States)

    Hedayatpour, N; Arendt-Nielsen, L; Falla, D

    2014-04-01

    Contracting the knee flexor muscles immediately before a maximum voluntary contraction (MVC) of knee extension increases the maximal force that the extensor muscles can exert. It is hypothesized that this phenomenon can be impaired by muscle fiber damage following eccentric exercise [delayed onset muscle soreness (DOMS)]. This study investigates the effect of eccentric exercise and DOMS on knee extension MVC immediately following a reciprocal-resisted knee flexion contraction. Electromyography (EMG) was recorded from the knee extensors and flexors of 12 healthy men during knee extension MVCs performed in a reciprocal (maximal knee extension preceded by resisted knee flexion), and nonreciprocal condition (preceded by relaxation of the knee flexors). At baseline, knee extension MVC force was greater during the reciprocal condition (P eccentric exercise, the MVC force was not different between conditions. Similarly, at baseline, the EMG amplitude of the quadriceps during the MVC was larger for the reciprocal condition (P eccentric exercise abolished the facilitation of force production for the knee extensors, which normally occurs when maximum knee extension is preceded by activation of the knee flexors.

  1. Detection of deletion in the dystrophin gene of a patient with quadriceps myopathy.

    Directory of Open Access Journals (Sweden)

    Kumari D

    2000-01-01

    Full Text Available A 43 year old male presented with slowly progressive weakness of limbs and hypertrophy of triceps, brachioradialis and calf muscles for four years. There was thinning of quadriceps muscles in both thighs. Histological study was compatible with Becker muscular dystrophy (BMD. Genomic DNA analysis showed a deletion of the Hind III fragments, spanning exons 45-47. A junction fragment of 11.0 kb was observed along with a deletion of a 3.4 kb PstI fragment containing exon 51 in the patient, and in one of his two sisters. The clinical and laboratory characteristics in this patient are in keeping with what has been described ′quadriceps myopathy′ and fall within the phenotypic variants of BMD as has been shown by others.

  2. Bilateral synchronous rupture of the quadriceps tendon.

    LENUS (Irish Health Repository)

    Ellanti, P

    2012-09-01

    Bilateral simultaneous rupture of the quadriceps tendon is a rare entity. They are often associated with degenerative changes of the tendons and predisposing conditions such as diabetes or excessive steroid use. They most commonly tend to occur in patients of 40 years of age or older.

  3. Proprioceptive neuromuscular facilitation and strength training to gain muscle strength in elderly women

    National Research Council Canada - National Science Library

    Cesário, Denise Ferreira; Mendes, Geovânia Barbosa da Silva; Uchôa, Érica Patrícia Borba Lira; Veiga, Paulo Henrique Altran

    2014-01-01

    ...: To perform comparative analyze of results of proprioceptive neuromuscular facilitation (PNF) techniques and strength training to gain muscle strength of biceps and quadriceps and grip in the elderly...

  4. Quadriceps Strength and Endurance After Posterior Cruciate Ligament Tears Versus Matched Group With Anterior Cruciate Ligament Tears.

    Science.gov (United States)

    Lee, Dae-Hee; Han, Seung-Beom; Lee, Jin-Hyuck; Lee, Seok-Joo; Suh, Dong-Won; Jeong, Hye-Jin

    2015-06-01

    This study was designed to compare the preoperative strengths and endurances of the quadriceps and hamstring muscles in patients with anterior cruciate ligament (ACL) versus posterior cruciate ligament (PCL) tears. Quadriceps and hamstring muscle strength and endurance were compared between 20 prospectively enrolled patients with isolated PCL tears and a retrospective, matched control group of 20 patients with isolated ACL tears. The maximal torque (60°/s) and total work (180°/s) of the quadriceps and hamstring were evaluated with an isokinetic testing device. Total work (1,094.4 ± 505.8 J v 797.5 ± 332.7 J, P = .035) and peak torque (129.9 ± 56.2 N ∙ m v 98.2 ± 37.4 N ∙ m, P = .046) of the quadriceps muscle on the involved side were higher in the PCL tear group than in the ACL tear group. However, there were no significant differences between the PCL tear group and ACL tear group in hamstring muscle strength (45.8 ± 42.3 N ∙ m and 46.0 ± 24.4 N ∙ m, respectively; P = .940) and endurance (429.3 ± 238.9 J and 382.4 ± 256.1 J, respectively; P = .574) on the involved side. The strength and endurance of the quadriceps muscle of the injured limb were greater after PCL tears than after ACL tears. However, there were no significant between-group differences in hamstring muscle strength and endurance on the involved side. Level III, retrospective comparative study. Copyright © 2015 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.

  5. Multi-parametric MR imaging of quadriceps musculature in the setting of clinical frailty syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Melville, David M.; Sharma, Puneet; Taljanovic, Mihra S. [University of Arizona College of Medicine, Department of Medical Imaging, 1501 N. Campbell Ave., P.O. Box 245067, Tucson, AZ (United States); Mohler, Jane; Fain, Mindy; Muchna, Amy E. [University of Arizona College of Medicine, Arizona Center on Aging, Tucson, AZ (United States); Krupinski, Elizabeth [University of Arizona College of Medicine, Department of Medical Imaging, 1501 N. Campbell Ave., P.O. Box 245067, Tucson, AZ (United States); Emory University, Department of Radiology and Imaging Services, Atlanta, GA (United States)

    2016-05-15

    Frailty is a common geriatric syndrome associated with loss of skeletal muscle mass (sarcopenia) conferring an increased risk of rapid decline in health and function with increased vulnerability to adverse outcomes. The purpose of this study was to investigate the correlation between diffusion tensor, T2 and intramuscular fat content values of the quadriceps muscle group and clinical frailty status using diffusion tensor MR imaging. Subjects were recruited from the Arizona Frailty cohort composed of all females with frailty status based on the Fried criteria, including 6 non-frail and 10 pre-frail/frail adults, as well as a community sample of 11 young, healthy controls. Axial images of both thighs were obtained on a 3-T magnet with T1, T2 and diffusion tensor imaging as well as intramuscular fat analysis. Diffusion tensor and T2 values were determined by region-of-interest measurements at the proximal, mid and distal thirds of both thighs. Data were evaluated to determine differences between measured values and frailty status. The mean fractional anisotropy (FA) values in the bilateral quadriceps muscles demonstrated significant differences (F = 7.558, p = 0.0030) between the control and pre-frail/frail and non-frail and pre-frail/frail groups. There was a significant difference in mean T2 (F = 21.675, p < 0.0001) and lipid content (F = 19.266, p < 0.0001) among all three groups in the total quadriceps muscle group. The quadriceps musculature of pre-frail/frail adults demonstrated increased FA compared to young controls and non-frail adults with increasing T2 and intramuscular fat among the control, non-frail and pre-frail/frail categories. (orig.)

  6. Effect of a Periodized Power Training Program on the Functional Performances and Contractile Properties of the Quadriceps in Sprinters

    Science.gov (United States)

    Kamandulis, Sigitas; Skurvydas, Albertas; Brazaitis, Marius; Stanislovaitis, Aleksas; Duchateau, Jacques; Stanislovaitiene, Jurate

    2012-01-01

    Our purpose was to compare the effect of a periodized preparation consisting of power endurance training and high-intensity power training on the contractile properties of the quadriceps muscle and functional performances in well trained male sprinters (n = 7). After 4 weeks of high-intensity power training, 60-m sprint running time improved by an…

  7. Identifying Dosage Effect of Light-Emitting Diode Therapy on Muscular Fatigue in Quadriceps.

    Science.gov (United States)

    Hemmings, Thomas J; Kendall, Kristina L; Dobson, John L

    2017-02-01

    Hemmings, TJ, Kendall, KL, and Dobson, JL. Identifying dosage effect of light-emitting diode therapy on muscular fatigue in quadriceps. J Strength Cond Res 31(2): 395-402, 2017-The purpose of this study was to compare the effects of various dosages of light-emitting diode therapy (LEDT) on muscle fatigue while performing a single-leg extension to exhaustion. A total of 34 recreationally resistance-trained athletes between the ages of 18 and 26 participated in 4 trials. Each trial included pre-exercise/postexercise blood lactate measurements and 2 sets of 3 maximal voluntary isometric contractions (MVICs), followed by LEDT on 6 points across the superficial quadriceps. Each randomized trial consisted of a placebo, 30, 60, or 120 seconds on each point on the quadriceps. Three minutes after LEDT, the participants performed an eccentric leg extension with 120% of MVIC until fatigue. There was significant increase in the number of repetitions performed between the placebo treatment and 60 seconds (p = 0.023), as well as placebo and 120 seconds (p = 0.004) of irradiation on each point. There were no significant differences in blood lactate levels between any of the 4 trials. In conclusion, LEDT had a positive effect on performance when irradiating 6 points on the superficial quadriceps for 60 and 120 seconds before an eccentric leg extension.

  8. Relation between body mass index percentile and muscle strength and endurance

    Directory of Open Access Journals (Sweden)

    Noha Abdel Kader Abdel Kader Hasan

    2016-10-01

    Conclusion: The study shows that the BMI of children had a positive correlation with the muscle strength of quadriceps, triceps, and abdominal muscles while a negative correlation with the endurance time of these muscles.

  9. Muscle size, neuromuscular activation, and rapid force characteristics in elderly men and women

    DEFF Research Database (Denmark)

    Suetta, C; Aagaard, P; Magnusson, S P

    2007-01-01

    quadriceps muscle cross-sectional area (LCSA), contractile rate of force development (RFD, Delta force/Delta time), impulse (integral force dt), muscle activation deficit (interpolated twitch technique), maximal neuromuscular activity [electromyogram (EMG)], and antagonist muscle coactivation in elderly men...

  10. Reduced Quadriceps Motor-Evoked Potentials in an Individual with Unilateral Knee Osteoarthritis: A Case Report

    Directory of Open Access Journals (Sweden)

    Michael A. Hunt

    2011-01-01

    Full Text Available One male with unilateral osteoarthritis (OA of the knee underwent testing of corticospinal (CS excitability (as quantified from motor-evoked potentials (MEPs in the rectus femoris (RF using transcranial magnetic stimulation and quadriceps muscle strength. Baseline data indicated reduced MEP amplitudes in the RF of the affected limb compared to the unaffected limb. Increases in RF MEP amplitudes from both limbs were observed immediately following a 30-minute exercise session focusing on muscle strengthening. Following an 8-week muscle strengthening intervention, the participant exhibited increased MEP amplitudes and muscle strength in the affected limb. These findings suggest that alterations in peripheral muscle function found in patients with knee OA may have an origin centrally within the motor cortex and that interlimb differences may be evident in those with unilateral disease. These findings also suggest that CS excitability may be improved following a muscle strengthening intervention.

  11. Dynamic in vivo 3-dimensional moment arms of the individual quadriceps components.

    Science.gov (United States)

    Wilson, Nicole A; Sheehan, Frances T

    2009-08-25

    The purpose of this study was to provide the first in vivo 3-dimensional (3D) measures of knee extensor moment arms, measured during dynamic volitional activity. The hypothesis was that the vastus lateralis (VL) and vastus medialis (VM) have significant off-axis moment arms compared to the central quadriceps components. After obtaining informed consent, three 3D dynamic cine phase contrast (PC) MRI sets (x,y,z velocity and anatomic images) were acquired from 22 subjects during active knee flexion and extension. Using a sagittal-oblique and two coronal-oblique imaging planes, the origins and insertions of each quadriceps muscle were identified and tracked through each time frame by integrating the cine-PC velocity data. The moment arm (MA) and relative moment (RM, defined as the cross product of the tendon line-of-action and a line connecting the line-of-action with the patellar center of mass) were calculated for each quadriceps component. The tendencies of the VM and VL to produce patellar tilt were evenly balanced. Interestingly, the magnitude of RM-P(Spin) for the VM and VL is approximately four times greater than the magnitude of RM-P(Tilt) for the same muscles suggesting that patellar spin may play a more important role in patellofemoral kinematics than previously thought. Thus, a force imbalance that leads to excessive lateral tilt, such as VM weakness in patellofemoral pain syndrome, would produce excessive negative spin (positive spin: superior patellar pole rotates laterally) and to a much greater degree. This would explain the increased negative spin found in recent studies of patellar maltracking. Assessing the contribution of each quadriceps component in three dimensions provides a more complete understanding of muscle functionality.

  12. Delayed reconstruction of a quadriceps tendon.

    Science.gov (United States)

    Pocock, C A J; Trikha, S P; Bell, J S P

    2008-01-01

    Rupture of the quadriceps tendon is an uncommon injury and rapid diagnosis is important because delay in surgical repair generally is believed to adversely affect outcome. One study of 20 patients suggests repair should be done during the first 48 to 72 hours postinjury to achieve a successful outcome and late repair led to unsatisfactory recovery. Cases of delayed tendon repair have been reported, the longest to our knowledge being 11 months before surgical intervention. We present a case of successful outcome of a quadriceps tendon rupture reconstructed at least 8 years after occurrence and a review of the literature of delayed reconstructions. We show that successful restoration of extensor mechanism function can be achieved several years after tendon rupture.

  13. Effect of Acupoint Injection of Mouse Nerve Growth Factor to Improvement of the mMuscular Tension of the Quadriceps Femoris Muscle of Child with Spastic Cerebral Palsy%鼠神经生长因子穴位注射对痉挛型脑瘫患儿股四头肌肌力的影响

    Institute of Scientific and Technical Information of China (English)

    徐成娥; 武光丽; 邓欣云

    2015-01-01

    目的:观察鼠神经生长因子穴位注射对痉挛型脑瘫患儿股四头肌肌力的影响.方法:将64例患者随机分为治疗组32例与对照组32例.分别在治疗前、治疗后1M、2M、3M进行肌电测试.治疗组鼠神经生长因子穴位注射配合康复训练.对照组生理盐水穴位注射配合康复训练.肌电信号采集应用加拿大ThoughtTechnology公司生产的表面肌电仪及Ag/Agcl表面电极.结果:治疗1M初次经行肌电测试时,2组患者股四头肌肌电无统计学意义(P>0.05).治疗2M测试时,治疗组的股四头肌肌电较对照组出现差异(P<0.05).治疗3M股四头肌肌电较对照组均出现显著差异,且2组差异增大.结论:鼠神经生长因子穴位注射对痉挛型脑瘫患儿股四头肌肌力的提高生理盐水穴位注射配合康复训练效果显著.%Objective: To observe the effect of acupoint injection of MouseNerveGrowthFactor (MNGF) to improvement of the muscular tension of the quadriceps femoris muscle of children with spastic cerebral palsy.Methods:64 cases of infantile cerebral palsy children were divided into treating group(32 cases) and control group(32 cases).The treatment group was given acupoint injection with MNGF accompanied by normal rehabilitation training.The control group was given acupoints infection with saline accompanied by normal rehabilitation training.The electromyogram (EMG) was tested pre- and post treatment (one month,two months and three months after treatment respectively);To test surface EMG (sEMG),surface EMG instrument and Ag/Agcl surface electrode produced by Thought Technology Company were used.Results:No significant difference was found between the two groups when the sEMG was compared between pre- and post treatment for one month.Significant difference was found between the two groups after two months treatment(P<0.05).Significant difference was found between the two groups after three months treatment After Three months treatment

  14. Light microscopic histology of quadriceps tendon ruptures.

    Science.gov (United States)

    Maffulli, Nicola; Del Buono, Angelo; Spiezia, Filippo; Longo, Umile Giuseppe; Denaro, Vincenzo

    2012-11-01

    To assess histological changes and possible differences in the quadriceps of patients undergoing open repair of the tendon after spontaneous rupture, and subjects with no history of tendon pathology. Biopsies were harvested from the quadriceps tendon of 46 patients (34 men, 12 women) who had reported unilateral atraumatic quadriceps tendon rupture and had undergone surgical repair of the tendon. Samples were also harvested from both the tendons in 11 (N = 11 × 2) patients, nine males and two females, dying from cardiovascular disorders. For each tendon, three slides were randomly selected and examined under light microscopy, and assessed using a semiquantitative grading scale (range 0-21) which considers fibre structure, fibre arrangement, rounding of the nuclei, regional variations in cellularity, increased vascularity, decreased collagen stainability, and hyalinisation. The pathological sum-score averaged 19.2 ± 3.7 in ruptured tendons and 5.6 ± 2.0 in controls, and all variables considered were significantly different between the two groups, showing an association between tendon abnormalities and rupture (0.05 tendons increases the risk of rupture.

  15. Rapid hamstring/quadriceps force capacity in male vs. female elite soccer players.

    Science.gov (United States)

    Zebis, Mette K; Andersen, Lars L; Ellingsgaard, Helga; Aagaard, Per

    2011-07-01

    Knee joint injuries are a serious issue in soccer. The ability to protect the knee from injury depends largely on the strength of the hamstring relatively to the quadriceps, that is, a low hamstring/quadriceps (H/Q) strength ratio is suggested as a risk factor. Although maximal muscle strength (MVC) has often been used to evaluate the H/Q ratio, the ability to rapidly develop force (rate of force development [RFD]) is more relevant in relation to fast dynamic movements. The aim of this study was to introduce and investigate a rapid RFD H/Q strength ratio compared with the traditional MVC H/Q strength ratio in elite soccer players. Twenty-three elite soccer players (11 women, 12 men) performed maximal voluntary static contraction for the hamstring and quadriceps in an isokinetic dynamometer, from which the maximal muscles strength (MVC) and RFD were extracted. Test-retest reliability for the RFD H/Q ratio was high (intraclass correlation coefficient = 0.664-0.933). The initial contraction phase up to 50 milliseconds from the onset of contraction showed a low RFD H/Q ratio compared to the MVC H/Q ratio (p rupture at a later occasion. The high reliability of the new RFD H/Q strength ratio indicates that the method is a relevant tool in standardized clinical evaluation of the knee joint agonist-antagonist relationship.

  16. A Study on the Differences of Quadriceps Femoris Activities by Knee Alignment during Isometric Contraction.

    Science.gov (United States)

    Park, Seol; Ko, Yu-Min; Jang, Gwon-Uk; Hwang, Yoon-Tae; Park, Ji-Won

    2014-11-01

    [Purpose] This study attempted to identify how genu varum or valgum affects the electromyographic activities of the vastus medialis, vastus lateralis, and rectus femoris during knee isometric contraction. [Subjects] Fifty-two healthy young adults were enrolled in this study. They were enrolled and classified into three groups by knee alignment conditions: the genu varum, genu valgum, and control groups. [Methods] The electromyographic activity ratio of the vastus medialis to the vastus lateralis and rectus femoris were calculated using the percentage of maximum voluntary contraction. The participants contracted their quadriceps during isometric contraction at 30 and 60° of knee flexion. [Results] The genu varum group had more activity in the vastus medialis than in the vastus lateralis and rectus femoris, whereas the genu valgum group had more activity in the vastus lateralis and rectus femoris than in the vastus medialis. There was a significant difference in the muscle activity ratio between the vastus medialis and vastus lateralis by angle of knee flexion degree only in the genu valgum. There were no significant differences in any of the three groups in terms of the muscle activity ratio of the vastus medialis to the rectus femoris by angle of knee flexion. [Conclusion] The quadriceps femoris was used for different strategies according to knee alignment during isometric contraction at 30 and 60°. This study suggests that rehabilitation training programs used to strengthen the quadriceps should consider the knee alignment conditions of the target subjects.

  17. Acute effects of static stretching on peak torque and the hamstrings-to-quadriceps conventional and functional ratios.

    Science.gov (United States)

    Costa, P B; Ryan, E D; Herda, T J; Walter, A A; Defreitas, J M; Stout, J R; Cramer, J T

    2013-02-01

    Recent evidence has shown acute static stretching may decrease hamstring-to-quadriceps (H:Q) ratios. However, the effects of static stretching on the functional H:Q ratio, which uses eccentric hamstrings muscle actions, have not been investigated. This study examined the acute effects of hamstrings and quadriceps static stretching on leg extensor and flexor concentric peak torque (PT), leg flexor eccentric PT, and the conventional and functional H:Q ratios. Twenty-two women (mean ± SD age=20.6 ± 1.9 years; body mass=64.6 ± 9.1 kg; height=164.5 ± 6.4 cm) performed three maximal voluntary unilateral isokinetic leg extension, flexion, and eccentric hamstring muscle actions at the angular velocities of 60 and 180°/s before and after a bout of hamstrings, quadriceps, and combined hamstrings and quadriceps static stretching, and a control condition. Two-way repeated measures ANOVAs (time × condition) were used to analyze the leg extension, flexion, and eccentric PT as well as the conventional and functional H:Q ratios. Results indicated that when collapsed across velocity, hamstrings-only stretching decreased the conventional ratios (Pratios (Pratios.

  18. High-Velocity Quadriceps Exercises Compared to Slow-Velocity Quadriceps Exercises Following Total Knee Arthroplasty: A Randomized Clinical Study.

    Science.gov (United States)

    Doerfler, Deborah; Gurney, Burke; Mermier, Christine; Rauh, Mitchell; Black, Liza; Andrews, Ron

    2016-01-01

    Despite improvement in pain and perceived function in older adults following total knee arthroplasty (TKA), objective outcome measures of muscular impairment and ambulatory function demonstrate significant deficits. Evidence suggests that quadriceps power may play a greater role in ambulatory function than measures of strength alone following TKA. The purpose of this study was to compare the effect of high-velocity (HV) quadriceps exercises with that of slow-velocity (SV) quadriceps exercises on functional outcomes and quadriceps power following TKA. This study was a randomized clinical study conducted in an outpatient physical therapy clinic. Twenty-one participants who were 4 to 6 weeks post unilateral TKA were randomly assigned to an HV or SV group. Participants performed an evidence-based standardized progressive resistance exercise program in addition to HV quadriceps exercises or SV quadriceps exercises. Participants attended 2 sessions per week for 8 weeks. Before and after the 8-week exercise intervention, participants completed a functional questionnaire, health survey, functional testing, and underwent quadriceps strength and power testing. Both groups demonstrated improvements in ambulatory outcome measures, strength, speed, and power. The HV group demonstrated significantly greater improvements in distance walked and quadriceps strength than the SV group. These data should be considered preliminary because of a small sample size. HV quadriceps exercises may be an effective rehabilitation strategy in conjunction with a standardized progressive resistance exercise program beginning 4 to 6 weeks after TKA.

  19. A dynamic warm-up model increases quadriceps strength and hamstring flexibility.

    Science.gov (United States)

    Aguilar, Alain J; DiStefano, Lindsay J; Brown, Cathleen N; Herman, Daniel C; Guskiewicz, Kevin M; Padua, Darin A

    2012-04-01

    Research suggests that static stretching can negatively influence muscle strength and power and may result in decreased functional performance. The dynamic warm-up (DWU) is a common alternative to static stretching before physical activity, but there is limited research investigating the effects of a DWU. The purpose of this study was to compare the acute effects of a DWU and static stretching warm-up (SWU) on muscle flexibility, strength, and vertical jump using a randomized controlled trial design. Forty-five volunteers were randomly assigned into a control (CON), SWU, or DWU group. All participants rode a stationary bicycle for 5 minutes and completed a 10-minute warm-up protocol. During this protocol, the DWU group performed dynamic stretching and running, the SWU group performed static stretching, and the CON group rested. Dependent variables were measured immediately before and after the warm-up protocol. A digital inclinometer measured flexibility (degrees) for the hamstrings, quadriceps, and hip flexor muscles. An isokinetic dynamometer measured concentric and eccentric peak torque (N·m/kg) for the hamstrings and quadriceps. A force plate was used to measure vertical jump height (meters) and power (watts). In the DWU group, there was a significant increase in hamstring flexibility (pretest: 26.4 ± 13.5°, posttest: 16.9 ± 9.4°; p 0.05). The DWU significantly improved eccentric quadriceps strength and hamstrings flexibility, whereas the SWU did not facilitate any positive or negative changes in muscle flexibility, strength, power, or vertical jump. Therefore, the DWU may be a better preactivity warm-up choice than an SWU.

  20. Gastrocnemius myotendinous flap for patellar or quadriceps tendon repair, or both.

    Science.gov (United States)

    Rhomberg, M; Schwabegger, A H; Ninkovic, M; Bauer, T; Ninkovic, M

    2000-08-01

    The authors' experience with simultaneous reconstruction of the quadriceps femoris or patellar tendon or both and soft tissue defect using a musculotendinous unit of the gastrocnemius muscle is presented. Five patients with a partial or complete defect of the quadriceps or patellar tendon or both and additional large soft tissue defects underwent reconstruction applying this technique as a one-stage surgical procedure in different variations. In cases with a partial defect of the tendon or loss of tendon thickness, the thick aponeurosis from the deeper aspect of the gastrocnemius was dissected and transferred as a pedicled tendon flap to reconstruct the tendon defect. In cases with a complete defect of the tendon, the superficial layer of the Achilles tendon together with the deep aponeurotic layer of the gastrocnemius muscle served to reconstruct the tendon. In both procedures the gastrocnemius muscle belly provided soft tissue coverage and was covered with a split thickness skin graft. One patient had a marginal deep necrosis develop that had to be covered with the other gastrocnemius muscle in a second operation. One patient with chronic polyarthritis and infection of his knee prosthesis declined additional reconstruction surgery and had the leg amputated. The average followup was 3.5 years. All patients achieved good results in active extension of the knee with an extension deficit of only 5 degrees to 15 degrees. The range of flexion was at least 90 degrees. The surgical technique described in this report provides functional tendon reconstruction and adequate soft tissue repair simultaneously.

  1. Understanding and Treating Arthrogenic Muscle Inhibition

    Institute of Scientific and Technical Information of China (English)

    Brian G. Pietrosimone; M. Ed, ATC

    2009-01-01

    @@ Quadriceps muscle weakness and dysfunction are common consequences of knee joint injury or effusion.[1-7] Deficits in quadriceps muscle function have been reported following various knee joint pathologies including anterior knee pain, [8-11] anterior cruciate ligament injury, [6,7,12-22] knee joint osteoarthritis,[2,23,24] and meniscus injury.[5,25] Muscle strengthening is regularly the focus of rehabilita-tion regimens,yet,full quadriceps strength is often not re-gained following discharge from formal physical therapy sessions. [19] Additionally some evidence suggests that quadriceps weakness persists long after acute knee joint injury[21] and may be a contributing factor to the onset of osteoarthritis.

  2. Osteoarthritis of knee joint - role of quadriceps exercises

    Directory of Open Access Journals (Sweden)

    M.A.Q. Ansari

    2014-08-01

    Conclusions: There is relationship between age, sex and quadriceps exercise with osteoarthritis of knee. Moderate quadriceps exercise is a safe and effective prevention and therapy for Osteoarthritis of knee. [Int J Res Med Sci 2014; 2(4.000: 1652-1654

  3. Quadriceps Strength and Executive Functions in Older Women

    NARCIS (Netherlands)

    Scherder, E. J. A.; Eggermont, L. H. P.; Geuze, R. H.; Vis, J.; Verkerke, G. J.

    2010-01-01

    Objective: The aim of this study is to answer the question whether the strength of the knee extensor musculus quadriceps (m. quadriceps), in particular, is related to specific executive functions and whether this relationship is independent of aerobic fitness. The clinical relevance of this question

  4. Effects of preoperative neuromuscular electrical stimulation on quadriceps strength and functional recovery in total knee arthroplasty. A pilot study

    Directory of Open Access Journals (Sweden)

    O'Gorman Donal J

    2010-06-01

    Full Text Available Abstract Background Supervised preoperative muscle strengthening programmes (prehabilitation can improve recovery after total joint arthroplasty but are considered resource intensive. Neuromuscular electrical stimulation (NMES has been shown to improve quadriceps femoris muscle (QFM strength and clinical function in subjects with knee osteoarthritis (OA however it has not been previously investigated as a prehabilitation modality. Methods This pilot study assessed the compliance of a home-based, NMES prehabilitation programme in patients undergoing total knee arthroplasty (TKA. We evaluated its effect on preoperative and postoperative isometric quadriceps femoris muscle (QFM strength, QFM cross-sectional area (CSA and clinical function (subjective and objective. Seventeen subjects were recruited with 14 completing the study (NMES group n = 9; Control group n = 5. Results Overall compliance with the programme was excellent (99%. Preoperative QFM strength increased by 28% (p > 0.05 with associated gains in walk, stair-climb and chair-rise times (p 0.05 at 12 weeks postoperatively compared to baseline. There were only limited associations found between objective and subjective functional outcome instruments. Conclusions This pilot study has shown that preoperative NMES may improve recovery of quadriceps muscle strength and expedite a return to normal activities in patients undergoing TKA for OA. Recommendations for appropriate outcome instruments in future studies of prehabilitation in TKA have been provided.

  5. 髌股疼痛综合征患者股四头肌失衡程度评估及其与Q角的相关分析%Correlation analysis on the imbalance of quadriceps muscle and Q angle in patients with PFPS

    Institute of Scientific and Technical Information of China (English)

    缪萍; 王楚怀; 潘翠环; 于瑞

    2012-01-01

    Objective To assess the imbalance of quadriceps muscle in the patients with PFPS by sEMG and investigate the possible relationship with Q angles. Methods 30 patients with PFPS and 30 healthy subjects were enrolled as the study group and the control group. Q angles were measured in all subjects. Bilateral VL and VMO activities were recorded with sEMG during double-leg semisquat (DLSS). Results In the study group, the differences of the time domain indexes (ZCR, RMS, IEMG) between VL and VMO were significant in the test of DLSS (P < 0.05). There was no significant relationship between Q angle and the VL/ VMO myoelectricity ratio (P < 0.05). Conclusions VL had higher degree of activation and motor unit recruitment than VMO in PFPS. It was not conclusive whether the Q angle is related to the occurrence or the severity of PFPS.%目的:利用表面肌电图对髌股疼痛综合征(PFPS)患者股四头肌失衡程度进行评估,并对其与Q角的关系进行分析.方法:PFPS病例组及正常对照组各30人,分别进行Q角测量,同时在双足半蹲动作时检测股外侧肌(VL)及股内斜肌(VMO)表面肌电图(sEMG),分析股内、外侧肌时域指标,对Q角与VL/VMO肌电比值进行相关分析.结果:病例组VL、VMP时域指标ZCR、RMS、IEMG差异有统计学意义(P<0.05),且VL较VMO高.Q角与VL/VMO肌电比值之间进行线性相关分析,Pearson相关系数为0.149(P> 0.05).结论:PFPS患者VL运动单位募集数量、活化程度要高于VMO.股四头肌失衡程度与Q角大小无明显相关.

  6. Fatigue affects peak joint torque angle in hamstrings but not in quadriceps.

    Science.gov (United States)

    Coratella, Giuseppe; Bellin, Giuseppe; Beato, Marco; Schena, Federico

    2015-01-01

    Primary aim of this study was to investigate peak joint torque angle (i.e. the angle of peak torque) changes recorded during an isokinetic test before and after a fatiguing soccer match simulation. Secondarily we want to investigate functional Hecc:Qconc and conventional Hconc:Qconc ratio changes due to fatigue. Before and after a standardised soccer match simulation, twenty-two healthy male amateur soccer players performed maximal isokinetic strength tests both for hamstrings and for quadriceps muscles at 1.05 rad · s(‒1), 3.14 rad · s(‒1) and 5.24 rad · s(‒1). Peak joint torque angle, peak torque and both functional Hecc:Qconc and conventional Hconc:Qconc ratios were examined. Both dominant and non-dominant limbs were tested. Peak joint torque angle significantly increased only in knee flexors. Both eccentric and concentric contractions resulted in such increment, which occurred in both limbs. No changes were found in quadriceps peak joint torque angle. Participants experienced a significant decrease in torque both in hamstrings and in quadriceps. Functional Hecc:Qconc ratio was lower only in dominant limb at higher velocities, while Hconc:Qconc did not change. This study showed after specific fatiguing task changes in hamstrings only torque/angle relationship. Hamstrings injury risk could depend on altered torque when knee is close to extension, coupled with a greater peak torque decrement compared to quadriceps. These results suggest the use eccentric based training to prevent hamstrings shift towards shorter length.

  7. THE EFFECTS OF VARIED TENSIONS OF KINESIOLOGY TAPING ON QUADRICEPS STRENGTH AND LOWER LIMB FUNCTION.

    Science.gov (United States)

    de Jesus, Julio Fernandes; Franco, Yuri Rafael Dos Santos; Nannini, Stella Bispo; Nakaoka, Gustavo Bezerra; Dos Reis, Amir Curcio; Bryk, Flavio Fernandes

    2017-02-01

    Kinesiology Taping (KT) may promote changes in muscle strength and motor performance, topics of great interest in the sports-medicine sciences. These characteristics are purported to be associated with the tension generated by the KT on the skin. However, the most suitable tension for the attainment of these strength and performance effects has not yet been confirmed. The purpose of the present study was to analyze the effects of different tensions of KT on the isometric contraction of the quadriceps and lower limb function of healthy individuals over a period of seven days. Blind, randomized, clinical trial. One hundred and thirty healthy individuals were distributed into the following five groups: control (without KT); KT0 (KT without tension); KT50; KT75 and KT100 (approximately 50%, 75% and 100% tension applied to the tape, respectively). Assessments of isometric quadriceps strength were conducted using a hand held dynamometer. Lower limb function was assessed through Single Hop Test for Distance, with five measurement periods: baseline; immediately after KT application; three days after KT; five days after KT; and 72h after KT removal (follow-up). There were no statistically significant differences (p > 0.05) at any of the studied periods on participants' quadriceps strength nor in the function of the lower dominant limb, based on comparisons between the control group and the experimental groups. KT applied with different tensions did not produce modulations, in short or long-term, on quadriceps' strength or lower limb function of healthy individuals. Therefore, this type of KT application, when seeking these objectives, should be reconsidered. 1b.

  8. The Effect of NeuroMuscular Electrical Stimulation on Quadriceps Strength and Knee Function in Professional Soccer Players: Return to Sport after ACL Reconstruction

    Directory of Open Access Journals (Sweden)

    J. Taradaj

    2013-01-01

    Full Text Available The aim of this study was to assess the clinical efficacy and safety of NMES program applied in male soccer players (after ACL reconstruction on the quadriceps muscle. The 80 participants (NMES = 40, control = 40 received an exercise program, including three sessions weekly. The individuals in NMES group additionally received neuromuscular electrical stimulation procedures on both right and left quadriceps (biphasic symmetric rectangular pulses, frequency of impulses: 2500 Hz, and train of pulses frequency: 50 Hz three times daily (3 hours of break between treatments, 3 days a week, for one month. The tensometry, muscle circumference, and goniometry pendulum test (follow-up after 1 and 3 months were applied. The results of this study show that NMES (in presented parameters in experiment is useful for strengthening the quadriceps muscle in soccer athletes. There is an evidence of the benefit of the NMES in restoring quadriceps muscle mass and strength of soccer players. In our study the neuromuscular electrical stimulation appeared to be safe for biomechanics of knee joint. The pathological changes in knee function were not observed. This trial is registered with Australian and New Zealand Clinical Trials Registry ACTRN12613001168741.

  9. The effect of neuromuscular electrical stimulation on quadriceps strength and knee function in professional soccer players: return to sport after ACL reconstruction.

    Science.gov (United States)

    Taradaj, J; Halski, T; Kucharzewski, M; Walewicz, K; Smykla, A; Ozon, M; Slupska, L; Dymarek, R; Ptaszkowski, K; Rajfur, J; Pasternok, M

    2013-01-01

    The aim of this study was to assess the clinical efficacy and safety of NMES program applied in male soccer players (after ACL reconstruction) on the quadriceps muscle. The 80 participants (NMES = 40, control = 40) received an exercise program, including three sessions weekly. The individuals in NMES group additionally received neuromuscular electrical stimulation procedures on both right and left quadriceps (biphasic symmetric rectangular pulses, frequency of impulses: 2500 Hz, and train of pulses frequency: 50 Hz) three times daily (3 hours of break between treatments), 3 days a week, for one month. The tensometry, muscle circumference, and goniometry pendulum test (follow-up after 1 and 3 months) were applied. The results of this study show that NMES (in presented parameters in experiment) is useful for strengthening the quadriceps muscle in soccer athletes. There is an evidence of the benefit of the NMES in restoring quadriceps muscle mass and strength of soccer players. In our study the neuromuscular electrical stimulation appeared to be safe for biomechanics of knee joint. The pathological changes in knee function were not observed. This trial is registered with Australian and New Zealand Clinical Trials Registry ACTRN12613001168741.

  10. Altered mitochondrial regulation in quadriceps muscles of patients with COPD

    DEFF Research Database (Denmark)

    Naimi, Ashley I; Bourbeau, Jean; Perrault, Helene

    2011-01-01

    to complex I (COPD 38·28 ± 3·58 versus control 42·85 ± 3·10 pmol s(-1) mg tissue(-1) ), but O(2) flux with addition of succinate was lower in COPD patients (COPD 63·72 ± 6·33 versus control 95·73 ± 6·53 pmol s(-1) mg tissue(-1) ); (iii) excess capacity of cytochrome c oxidase in COPD patients was only ~50...

  11. The Relationship between Lean Mass and Contractile Properties of the Quadriceps in Elderly and Young Adults.

    Science.gov (United States)

    Mau-Moeller, Anett; Bruhn, Sven; Bader, Rainer; Behrens, Martin

    2015-01-01

    Aging is associated with a loss of muscle mass (sarcopenia) and function. The twitch torque evoked by supramaximal electrical stimulation of peripheral nerves has been frequently used to analyse age-related modulations at the skeletal muscle level, such as changes in muscle mass. However, only one study has investigated the association between twitch contractile properties and skeletal muscle mass. A significant positive correlation between cross-sectional area and twitch parameters was found for the plantar flexors in young adults when using supramaximal doublet stimulation. It remains unclear whether this relationship exists for the quadriceps in elderly and young subjects when using single and doublet stimulation. The aim of the present study was to investigate the relationship between the lean mass of the thigh and evoked twitch properties of the quadriceps using single and doublet stimulation in two age groups. Fifteen young (aged 25.3 ± 3.6 years) and 15 elderly (aged 69.6 ± 3.1 years) subjects were recruited to participate in this study. The lean mass of the thigh was measured by dual-energy X-ray absorptiometry. Supramaximal single and doublet electrical stimulation was used to assess the contractile properties of the quadriceps. We observed no significant associations between lean mass and contractile properties when using single stimulation. Significant positive correlations were shown between lean mass and peak twitch torque evoked by doublet stimulation in young (r = 0.56; p = 0.030) and elderly (r = 0.54; p = 0.040) subjects. The analysis of twitch time and slope parameters demonstrated no significant correlations with lean mass. The peak twitch torque evoked by doublet electrical stimulation seems to be an appropriate measure to assess modulations in muscle mass in elderly and young subjects. The use of supramaximal single stimulation and the analysis of time and slope parameters may not be recommended for estimating changes in muscle mass

  12. EXERCISES THAT FACILITATE OPTIMAL HAMSTRING AND QUADRICEPS CO-ACTIVATION TO HELP DECREASE ACL INJURY RISK IN HEALTHY FEMALES: A SYSTEMATIC REVIEW OF THE LITERATURE.

    Science.gov (United States)

    Dedinsky, Rachel; Baker, Lindsey; Imbus, Samuel; Bowman, Melissa

    2017-01-01

    Background Anterior cruciate ligament (ACL) injury is common among females due to many anatomic, hormonal, and neuromuscular risk factors. One modifiable risk factor that places females at increased risk of ACL injury is a poor hamstrings: quadriceps (H:Q) co-activation ratio, which should be 0.6 or greater in order to decrease the stress placed on the ACL. Exercises that produce more quadriceps dominant muscle activation can add to the tension placed upon the ACL, potentially increasing the risk of ACL injury. Hypothesis/Purpose The purpose of this systematic review was to compare quadriceps and hamstring muscle activation during common closed kinetic chain therapeutic exercises in healthy female knees to determine what exercises are able to produce adequate H:Q co-activation ratios. Study Design Systematic Review Methods Multiple online databases were systematically searched and screened for inclusion. Eight articles were identified for inclusion. Data on mean electromyography (EMG) activation of both quadriceps and hamstring muscles, % maximal voluntary isometric contraction (MVIC), and H:Q co-activation ratios were extracted from the studies. Quality assessment was performed on all included studies. Results Exercises analyzed in the studies included variations of the double leg squat, variations of the single leg squat, lateral step-up, Fitter, Stairmaster® (Core Health and Fitness, Vancouver, WA), and slide board. All exercises, except the squat machine with posterior support at the level of the scapula and feet placed 50 cm in front of the hips, produced higher quadriceps muscle activation compared to hamstring muscle activation. Conclusion Overall, two leg squats demonstrate poor H:Q co-activation ratios. Single leg exercises, when performed between 30 and 90 degrees of knee flexion, produce adequate H:Q ratios, thereby potentially reducing the risk of tensile stress on the ACL and ACL injury. Level of Evidence 2a- Systematic Review of Cohort Studies PMID

  13. Late quadriceps tendon rupture at the donor site following cruciate ligament reconstruction using central quadriceps tendon graft.

    Science.gov (United States)

    Pandey, Vivek; Madi, Sandesh; Joseph, Amy; Acharya, Kiran

    2015-10-16

    Central quadriceps tendon (CQT) graft has been successfully used as a viable autograft option in cruciate ligament reconstruction of the knee. The prime emphasis in the majority of the literature is given to surgical details of quadriceps graft harvesting and outcome of cruciate ligament reconstruction. There is less discussion about donor site morbidity in CQT graft, and it is less frequent as compared to that in bone patellar tendon bone graft. We report an extremely unusual case of late quadriceps tendon rupture at the donor site following anterior cruciate ligament reconstruction using CQT graft.

  14. Complications in Brief: Quadriceps and Patellar Tendon Tears

    National Research Council Canada - National Science Library

    Volk, W Robert; Yagnik, Gautam P; Uribe, John W

    2014-01-01

    .... In particular, inappropriate surgical timing (especially late surgery), misplaced patellar drill holes, and failure to address concomitant injuries can result in complications seen when repairing a patellar or quadriceps tendon tear...

  15. Motor adaptations to unilateral quadriceps fatigue during a bilateral pedaling task.

    Science.gov (United States)

    Brøchner Nielsen, N-P; Hug, F; Guével, A; Fohanno, V; Lardy, J; Dorel, S

    2016-12-20

    This study was designed to investigate how motor coordination adapts to unilateral fatigue of the quadriceps during a constant-load bilateral pedaling task. We first hypothesized that this local fatigue would not be compensated within the fatigued muscles leading to a decreased knee extension power. Then, we aimed to determine whether this decrease would be compensated by between-joints compensations within the ipsilateral leg and/or an increased contribution of the contralateral leg. Fifteen healthy volunteers were tested during pedaling at 350 W before and after a fatigue protocol consisting of 15 minutes of electromyostimulation on the quadriceps muscle. Motor coordination was assessed from myoelectrical activity (22 muscles) and joint powers calculated through inverse dynamics. Maximal knee extension torque decreased by 28.3%±6.8% (P<.0005) immediately after electromyostimulation. A decreased knee extension power produced by the ipsilateral leg was observed during pedaling (-22.8±12.3 W, -17.0%±9.4%; P<.0005). To maintain the task goal, participants primarily increased the power produced by the non-fatigued contralateral leg during the flexion phase. This was achieved by an increase in hip flexion power confirmed by a higher activation of the tensor fascia latae. These results suggest no adjustment of neural drive to the fatigued muscles and demonstrate no concurrent ipsilateral compensation by the non-fatigued muscles involved in the extension pedaling phase. Although interindividual variability was observed, findings provide evidence that participants predominantly adapted by compensating with the contralateral leg during its flexion phase. Both neural (between legs) and mechanical (between pedals) couplings and the minimization of cost functions might explain these results.

  16. Ultrasound Diagnosis of Bilateral Quadriceps Tendon Rupture After Statin Use

    Directory of Open Access Journals (Sweden)

    Nesselroade, Ryan D

    2010-09-01

    Full Text Available Simultaneous bilateral quadriceps tendon rupture is a rare injury. We report the case of bilateral quadriceps tendon rupture sustained with minimal force while refereeing a football game. The injury was suspected to be associated with statin use as the patient had no other identifiable risk factors.The diagnosis was confirmed using bedside ultrasound. [West J Emerg Med. 2010; 11(4:306-309.

  17. [Simultaneous rupture of a patellar tendon and contralateral quadriceps tendon].

    Science.gov (United States)

    Horas, U; Ernst, S; Meyer, C; Halbsguth, A; Herbst, U

    2006-09-01

    The simultaneous bilateral rupture of the quadriceps tendon is a rare injury; only occasional reports exist about the bilateral simultaneous rupture of the patellar tendon. Degenerative changes of the tendon due to drugs or diseases lead to the rupture. We describe two cases of simultaneous rupture of the patellar and contralateral quadriceps tendons; only one patient had special risks. We report the management of therapy and the functional results using the Lysholm score and Knee Rating Scale.

  18. Knee extension and flexion muscle power after anterior cruciate ligament reconstruction with patellar tendon graft or hamstring tendons graft: a cross-sectional comparison 3 years post surgery

    DEFF Research Database (Denmark)

    Ageberg, Eva; Roos, Harald; Silbernagel, Karin

    2008-01-01

    to 2 years post surgery, but not later. In these studies, isokinetic muscle torque was used. However, muscle power has been suggested to be a more sensitive and sport-specific measures of strength. The aim was to study quadriceps and hamstring muscle power in patients with ACL injury treated...... for at least 4 months, were assessed with reliable, valid, and responsive tests of quadriceps and hamstring muscle power at 3 years (SD 0.9, range 2-5) after surgery. The mean difference between legs (injured minus uninjured), the hamstring to quadriceps (H:Q, hamstring divided by quadriceps) ratio....... The lower hamstring muscle power, and the lower hamstring to quadriceps ratio in the HT graft group than in the PT graft group 3 years (range 2-5) after ACL reconstruction, reflect imbalance of knee muscles after reconstruction with HT graft that may have a negative effect on dynamic knee...

  19. Physiological alterations of maximal voluntary quadriceps activation by changes of knee joint angle.

    Science.gov (United States)

    Becker, R; Awiszus, F

    2001-05-01

    The purpose of this study was to investigate the influence of different angles of the knee joint on voluntary activation of the quadriceps muscle, estimating the ability of a subject to activate a muscle maximally by means of voluntary contraction. Isometric torque measurement was performed on 6 healthy subjects in 5 degrees intervals between 30 degrees and 90 degrees of knee joint flexion. Superimposed twitches at maximal voluntary contraction (MVC) and at a level of 60% and 40% of the MVC were applied and the voluntary activation estimated. At between 30 degrees and 75 degrees of knee flexion, the maximal extension torque increased at an average rate of 2.67 +/- 0.6 Nm/degree, followed by a decline with further flexion. However, throughout the joint-angle range tested, voluntary activation increased on average by 0.37%/degree with a maximum at 90 degrees of flexion. Due to the influence of joint position it is not possible to generalize results obtained at the knee joint angle of 90 degrees of flexion, which is usually used for the quadriceps twitch-interpolation technique. Consequently, it is useful to investigate voluntary activation deficits in knee joint disorders at a range of knee joint angles that includes, in particular, the more extended joint angles used frequently during daily activity.

  20. Identification of electrically stimulated quadriceps - lower leg dynamics - the use of accelerometers for estimating knee joint acceleration and quadriceps torque

    NARCIS (Netherlands)

    Veltink, Peter H.; Tijsmans, Roel; Franken, Henry M.; Boom, Herman B.K.

    1992-01-01

    Knee joiiit acceleration aid quadriceps torque call be estbated from the signals of two tangentially yliiced accelerometers. This euables the ideutificatiou of qundriceps dynamics, loaded with a freely swiugiug lower leg, during electrical stimulation.

  1. Kinesio Taping Does Not Alter Quadriceps Isokinetic Strength and Power in Healthy Nonathletic Men: A Prospective Crossover Study

    Directory of Open Access Journals (Sweden)

    Paweł Korman

    2015-01-01

    Full Text Available Objectives. The effects of Kinesio Taping (KT on muscular performance remain largely unclear. This study aimed to investigate the acute effects of KT on the maximum concentric and eccentric quadriceps isokinetic strength. Study Design. This is a single-blinded, placebo crossover, repeated measures study. Methods. Maximum isokinetic concentric/eccentric extension torque, work, and power were assessed by an isokinetic dynamometer without taping (NT and with KT or placebo taping (PT in 17 healthy young men. Repeated measures one-way analysis of variance (ANOVA was used for statistical analyses. Results. Testing concentric contractions at 60°/s or 180°/s isokinetic speed, no significant differences in peak torque (Nm, total work (J, or mean power (W were noted among the application modes under different conditions. Testing eccentric contractions at 30°/s or 60°/s isokinetic speed, no significant differences in mentioned parameters were noted, respectively. KT on the quadriceps neither decreased nor increased muscle strength in the participants. Conclusion. KT application onto the skin overlying the quadriceps muscle does not enhance the strength or power of knee extensors in healthy men.

  2. Clinical thresholds for quadriceps assessment after anterior cruciate ligament reconstruction.

    Science.gov (United States)

    Kuenze, Christopher; Hertel, Jay; Saliba, Susan; Diduch, David R; Weltman, Arthur; Hart, Joseph M

    2015-02-01

    Normal, symmetrical quadriceps strength is a common clinical goal after anterior cruciate ligament reconstruction (ACLR). Currently, the clinical thresholds for acceptable unilateral quadriceps function and symmetry associated with positive outcomes after return to activity are unclear. To establish quadriceps-activation and knee-extension-torque cutoffs for clinical assessment after return to activity after ACLR. Descriptive laboratory study. Laboratory. 22 (10 female, 12 male; age = 22.5 ± 5.0 y, height = 172.9 ± 7.1 cm, mass = 74.1 ± 15.5 kg, months since surgery = 31.5 ± 23.5) recreationally active persons with a history of unilateral, primary ACLR at least 6 months prior and 24 (12 female/12 male, age = 21.7 ± 3.6 y, height = 168.0 ± 8.8 cm, mass = 69.3 ± 13.6 kg) recreationally active healthy participants. Patient-reported measures of pain, knee-related function, and physical activity level were recorded for all participants. Normalized knee-extension maximum-voluntary-isometric-contraction (MVIC) torque (Nm/kg) and quadriceps central-activation ratio (CAR, %) were measured bilaterally in all participants. Receiver-operator-characteristic (ROC) curves were used to establish thresholds for unilateral measures of normalized knee-extension MVIC torque and quadriceps CAR, as well as limb-symmetry indices (LSI). ROC curves then established clinical thresholds for normalized knee-extension MVIC torque and quadriceps CAR LSIs associated with healthy knee-related function. Involved-quadriceps CAR above 89.3% was the strongest unilateral indicator of healthy-group membership, while quadriceps CAR LSI above 0.996 and knee-extension MVIC torque above 0.940 were the strongest overall indicators. Unilateral normalized knee-extension MVIC torque above 3.00 Nm/kg and quadriceps CAR LSI above 0.992 were the best indicators of good patient-reported knee-related outcomes. Threshold values established in this study may provide a guide for clinicians when making return

  3. Treatment of knee arthrofibrosis and quadriceps insufficiency after patellar tendon repair: a case report including use of the graston technique.

    Science.gov (United States)

    Black, Douglass W

    2010-06-23

    Arthrofibrosis of the knee is a surgical complication that can limit range of motion, inhibit muscle activity, and decrease patient function. Optimal conservative treatment has not been well established in the literature, leaving a clinician with limited evidence for treatment planning. Described here is part of the rehabilitative course of care for a patient with arthrofibrotic limitations after a mid-substance patellar tendon repair with augmentation. Marked limitations in knee flexion range of motion and quadriceps activity were addressed using the Graston Technique to deal with soft-tissue adhesions; traditional physical therapy care was also provided. Clear improvement in range of motion and quadriceps activity and function was noted over the course of 5 treatments during 1 month. Treatment process and clinical reasoning are offered to promote understanding and to facilitate future inquiry.

  4. Quadriceps femoris electromyogram during concentric, isometric and eccentric phases of fatiguing dynamic knee extensions.

    Science.gov (United States)

    Pincivero, Danny M; Gandhi, Varsha; Timmons, Mark K; Coelho, Alan J

    2006-01-01

    The objective of this study was to examine the superficial quadriceps femoris (QF) muscle electromyogram (EMG) during fatiguing knee extensions. Thirty young adults were evaluated for their one-repetition maximum (1RM) during a seated, right-leg, inertial knee extension. All subjects then completed a single set of repeated knee extensions at 50% 1RM, to failure. Subjects performed a knee extension (concentric phase), held the weight with the knee extended for 2s (isometric phase), and lowered the weight in a controlled manner (eccentric phase). Raw EMG of the vastus medialis (VM), vastus lateralis (VL) and rectus femoris (RF) muscles were full-wave rectified, integrated and normalized to the 1RM EMG, for each respective phase and repetition. The EMG median frequency (f(med)) was computed during the isometric phase. An increase in QF muscle EMG was observed during the concentric phase across the exercise duration. VL EMG was greater than the VM and RF muscles during the isometric phase, in which no significant changes occurred in any of the muscles across the exercise duration. A significant decrease in EMG across the exercise duration was observed during the eccentric phase, with the VL EMG greater than the VM and RF muscles. A greater decrease in VL and RF muscle f(med) during the isometric phase, than the VM muscle, was observed with no gender differences. The findings demonstrated differential recruitment of the superficial QF muscle, depending on the contraction mode during dynamic knee extension exercise, where VL muscle dominance appears to manifest across the concentric-isometric-eccentric transition.

  5. Single cell morphology of muscle in patients with chronic muscle pain

    DEFF Research Database (Denmark)

    Jacobsen, Søren; Bartels, E M; Danneskiold-Samsøe, B

    1991-01-01

    In 119 patients referred with suspected fibromyalgia, biopsies from the quadriceps muscle were analyzed for "rubber band" morphology, and isokinetic quadriceps strength was measured. Eighty-four fulfilled the criteria for fibromyalgia, 26 had chronic myofascial pain (CMP) and 9 had other diseases...... to the biopsy score. "Rubber band" morphology is seen more often in fibromyalgia patients than in CMP patients. The exact genesis of this phenomenon is still unknown but theories connected with the possible pathogenesis of the syndrome are presented....

  6. Effects of Static and Dynamic Stretching on the Isokinetic Peak Torques and Electromyographic Activities of the Antagonist Muscles.

    Science.gov (United States)

    Serefoglu, Abdullah; Sekir, Ufuk; Gür, Hakan; Akova, Bedrettin

    2017-03-01

    The aim of this study was to investigate if static and dynamic stretching exercises of the knee muscles (quadriceps and hamstring muscles) have any effects on concentric and eccentric isokinetic peak torques and electromyographic amplitudes (EMG) of the antagonist muscles. Twenty healthy male athletes (age between 18-30 years) voluntarily participated in this study. All of the subjects visited the laboratory to complete the following intervention in a randomized order on 5 separate days; (a) non-stretching (control), (b) static stretching of the quadriceps muscles, (c) static stretching of the hamstring muscles, (d) dynamic stretching of the quadriceps muscles, and (e) dynamic stretching of the hamstring muscles. Static stretching exercises either for the quadriceps or the hamstring muscles were carried out at the standing and sitting positions. Subjects performed four successive repetitions of each stretching exercises for 30 seconds in both stretching positions. Similar to static stretching exercises two different stretching modes were designed for dynamic stretching exercises. Concentric and eccentric isokinetic peak torque for the non-stretched antagonist quadriceps or hamstring muscles at angular velocities of 60°/sec and 240°/sec and their concurrent electromyographic (EMG) activities were measured before and immediately after the intervention. Isokinetic peak torques of the non-stretched agonist hamstring and quadriceps muscles did not represent any significant (p > 0.05) differences following static and dynamic stretching of the antagonist quadriceps and hamstring muscles, respectively. Similarly, the EMG activities of the agonist muscles exhibited no significant alterations (p > 0.05) following both stretching exercises of the antagonist muscles. According to the results of the present study it is possible to state that antagonist stretching exercises either in the static or dynamic modes do not affect the isokinetic peak torques and the EMG activities

  7. Twitch interpolation technique in testing of maximal muscle strength

    DEFF Research Database (Denmark)

    Bülow, P M; Nørregaard, J; Danneskiold-Samsøe, B

    1993-01-01

    The aim was to study the methodological aspects of the muscle twitch interpolation technique in estimating the maximal force of contraction in the quadriceps muscle utilizing commercial muscle testing equipment. Six healthy subjects participated in seven sets of experiments testing the effects on...

  8. Dynamics of corticospinal changes during and after high-intensity quadriceps exercise.

    Science.gov (United States)

    Gruet, Mathieu; Temesi, John; Rupp, Thomas; Levy, Patrick; Verges, Samuel; Millet, Guillaume Y

    2014-08-01

    This study tested the hypothesis that during fatiguing quadriceps exercise, supraspinal fatigue develops late, is associated with both increased corticospinal excitability and inhibition and recovers quickly. Eight subjects performed 20 s contractions [15 s at 50% maximal voluntary contraction (MVC) followed by 5 s MVC] separated by a 10 s rest period until task failure. Transcranial magnetic stimulation (TMS) and electrical femoral nerve stimulation (PNS) were delivered ∼ 2 s apart during 50% MVC, during MVC and after MVC in relaxed muscle. Voluntary activation was assessed by TMS (VATMS) immediately before and after exercise and then three times over a 6 min recovery period. During exercise, MVC and twitch force evoked by PNS in relaxed muscle decreased progressively to 48 ± 8 and 36 ± 16% of control values, respectively (both P MVC were observed during the last quarter of exercise only (from 96.4 ± 1.7 to 86 ± 13%, P = 0.03 and from 0.76 ± 0.8 to 4.9 ± 4.7% MVC, P = 0.02, from baseline to task failure, respectively). The TMS-induced silent period increased linearly during both MVC (by ∼ 79 ms) and 50% MVC (by ∼ 63 ms; both P MVC and twitch force evoked by PNS in relaxed muscle recovered to only 84 ± 9 and 73 ± 17% of control values 6 min after exercise, respectively. In conclusion, high-intensity single-joint quadriceps exercise induces supraspinal fatigue near task failure, with increased intracortical inhibition and, in contrast to previous upper-limb results, unchanged corticospinal excitability. These changes recover rapidly after task failure, emphasizing the need to measure corticospinal adaptations immediately at task failure to avoid underestimation of exercise-induced corticospinal changes.

  9. [Neglected ipsilateral simultaneous ruptures of patellar and quadriceps tendon].

    Science.gov (United States)

    Karahasanoğlu, İlker; Yoloğlu, Osman; Kerimoğlu, Servet; Turhan, Ahmet Uğur

    2015-01-01

    Neglected patellar and quadriceps tendon rupture is a rare injury, but ipsilateral simultaneous patellar and quadriceps tendon rupture was not described in the literature to our knowledge. In this article, we report a 40-year-old healthy male patient with neglected ipsilateral patellar and quadriceps tendon ruptures treated by peroneus longus tendon autograft. Patient had received some conservative and surgical treatments for patellar fracture before applying to our clinic. After our treatment using peroneus longus autograft and interference nails, patient was immobilized for six weeks in cylindrical cast. Flexion exercises and full weight bearing were started after cast removal. Patient had no complaint at postoperative second year. Patient was a neglected case. Surgical repair and early rehabilitation enabled us to achieve a satisfactory outcome.

  10. [Quadriceps tendon insufficiency and rupture : Treatment options in total knee arthroplasty].

    Science.gov (United States)

    Thiele, K; von Roth, P; Pfitzner, T; Preininger, B; Perka, C

    2016-05-01

    Quadriceps tendon injuries and insufficiencies in total knee arthroplasty are rare, but are followed by a devastating complication that left untreated leads to a complete loss of function of the knee. This review article summarizes the functional anatomy, risk factors, and the prevalence and diagnosis of quadriceps tendon injuries, in addition to the possible management options for partial and complete ruptures. The treatment options are adapted according to the extent of the loss of function (partial, complete) and the duration of the injury (acute vs chronic). Furthermore, the choice of treatment should take into account the quality and availability of primary tissue, the patient's general health, along with their likely functional requirements. Conservative treatment is often justified in partial ruptures with good results. Complete ruptures require surgical intervention and multiple operative techniques are described. Treatment options for acute ruptures include direct primary repair with autogenous or synthetic tissue augmentation. In the case of chronic insufficiency and a lack of soft-tissue surroundings, reconstruction with the aid of a muscle flap or allograft tissue can be considered. All surgical intervention techniques used so far have been fraught with complications and rarely lead to satisfactory results. A new surgical approach to the reconstruction and augmentation of the extensor mechanism consists of the use of a synthetic mesh. The technique is described here in detail.

  11. Percutaneous quadriceps tendon pie-crusting release of extension contracture of the knee

    National Research Council Canada - National Science Library

    Liu, H X; Wen, H; Hu, Y Z; Yu, H C; Pan, X Y

    2014-01-01

    ...: percutaneous quadriceps tendon pie-crusting release. Percutaneous pie-crusting release was performed using an 18-gauge needle to puncture the stiff fibrous band of the distal and lateral quadriceps tendon under maximum knee flexion...

  12. The effect of local skin cooling before a sustained, submaximal isometric contraction on fatigue and isometric quadriceps femoris performance: A randomized controlled trial.

    Science.gov (United States)

    Hohenauer, Erich; Cescon, Corrado; Deliens, Tom; Clarys, Peter; Clijsen, Ron

    2017-04-01

    The central- and peripheral mechanisms by which heat strain limits physical performance are not fully elucidated. Nevertheless, pre-cooling is often used in an attempt to improve subsequent performance. This study compared the effects of pre-cooling vs. a pre-thermoneutral application on central- and peripheral fatigue during 60% of isometric maximum voluntary contraction (MVC) of the right quadriceps femoris muscle. Furthermore, the effects between a pre-cooling and a pre-thermoneutral application on isometric MVC of the right quadriceps femoris muscle and subjective ratings of perceived exertion (RPE) were investigated. In this randomized controlled trial, 18 healthy adults voluntarily participated. The participants received either a cold (experimental) application (+8°C) or a thermoneutral (control) application (+32°C) for 20min on their right thigh (one cuff). After the application, central (fractal dimension - FD) and peripheral (muscle fiber conduction velocity - CV) fatigue was estimated using sEMG parameters during 60% of isometric MVC. Surface EMG signals were detected from the vastus medialis and lateralis using bidimensional arrays. Immediately after the submaximal contraction, isometric MVC and RPE were assessed. Participants receiving the cold application were able to maintain a 60% isometric MVC significantly longer when compared to the thermoneutral group (mean time: 78 vs. 46s; p=0.04). The thermoneutral application had no significant impact on central fatigue (p>0.05) compared to the cold application (p=0.03). However, signs of peripheral fatigue were significantly higher in the cold group compared to the thermoneutral group (p=0.008). Pre-cooling had no effect on isometric MVC of the right quadriceps muscle and ratings of perceived exertion. Pre-cooling attenuated central fatigue and led to significantly longer submaximal contraction times compared to the pre-thermoneutral application. These findings support the use of pre-cooling procedures

  13. [Damage to large tendons: Achilles, patellar and quadriceps tendons].

    Science.gov (United States)

    Amlang, M H; Zwipp, H

    2006-07-01

    The etiology and mechanisms of Achilles, patellar and quadriceps tendon ruptures are very similar. Age dependent changes in tendon structure and disorders such gout, diabetes, rheumatic diseases and chronic renal failure are associated causes. The main mechanism of rupture is indirect trauma. Although clinical diagnosis is easy, ruptures are still frequently missed. Sonography is the main standard diagnostic tool. MRI is indicated only in special cases. Open operative repair is the most common treatment for quadriceps and patellar tendon ruptures. Treatment of Achilles tendon ruptures is moving towards an individualized choice of therapy. Percutaneous and other "minimally invasive" techniques will play an increasingly important role.

  14. Delayed presentation of compartment syndrome of the thigh secondary to quadriceps trauma and vascular injury in a soccer athlete.

    Science.gov (United States)

    How, Moo Ing; Lee, Puah Ken; Wei, Tan See; Chong, Chua Tai

    2015-01-01

    Compartment syndrome isolated to the anterior thigh is a rare complication of soccer injury. Previous reports in the English literature on sports trauma-related compartment syndrome of the thigh are vague in their description of the response of thigh musculature to blunt trauma, magnetic resonance imaging (MRI) findings of high-risk features of compartment syndrome, vascular injury in quadriceps trauma, and the role of vascular study in blunt thigh injury. We present herein the rare case of a 30-year-old man who developed thigh compartment syndrome 8 days after soccer injury due to severe edema of vastus intermedius and large thigh hematoma secondary to rupture of the profunda femoris vein. MRI revealed "blow-out" rupture of the vastus lateralis. Decompressive fasciotomy and vein repair performed with subsequent split-skin grafting of the wound defect resulted in a good functional outcome at 2-years follow-up. A high index of suspicion for compartment syndrome is needed in all severe quadriceps contusion. Vascular injury can cause thigh compartment syndrome in sports trauma. MRI findings of deep thigh muscle swelling and "blow-out" tear of the vastus lateralis are strongly suggestive of severe quadriceps injury, and may be a harbinger of delayed thigh compartment syndrome. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

  15. Reconstrução do ligamento cruzado anterior com o terço central do tendão do músculo quadríceps: análise de resultados após 10 anos Reconstruction of the anterior cruciate ligament with the central third of the quadriceps muscle tendon: analysis of 10-year results

    Directory of Open Access Journals (Sweden)

    Marcus Valladares Guimarães

    2009-01-01

    articulação femoropatelar.OBJECTIVE: Assess clinical results using two different protocols, 10 years after ACL reconstruction surgery with the central third of quadriceps muscle tendon (QT. METHOD: Between November /1997 and April/1998, 25 patients were submitted to 25 ACL reconstructions with QT by transtibial technique. The bone portion of the graft was fixated on femoral tunnel with interference screw and the tendinous portion of tibial tunnel with screw with washer. Two patients injured the new when playing soccer. Six patients were not available for follow-up (24%. Seventeen patients were evaluated, 15 men and two women, with mean age at surgery time of 28.53 ± 6.64 years. All patients were examined at six months, one year, and ten years after surgery. Clinical evaluation was made by the Lysholm scale, and the knee evaluation, with the Hospital for Special Surgery scale. RESULTS: The patients had their injuries operated after 9.87 ± 14.42 months of the accident. According to Lysholm scale, the results at the end of the first year were 98.71 ± 2.47 and, after 10 years, 97.35 ± 3.12. Using the Hospital for Special Surgery scale, the mean score was 95.07 ± 5.23 in one year, and 94.87 ± 4.16 in 10 years. All patients returned to their professional activities with the same previous status. Fifteen (88.24% patients were able to return to their sports activities, one by modifying the practice, while another one switched to another sport. No patient complained of pain on the donor area in the medium and long term. The sports return rate was excellent, and no changes were found on the femoropatellar joint.

  16. Impaired voluntary neuromuscular activation limits muscle power in mobility-limited older adults

    Science.gov (United States)

    Background. Age-related alterations of neuromuscular activation may contribute to deficits in muscle power and mobility function. This study assesses whether impaired activation of the agonist quadriceps and antagonist hamstrings, including amplitude- and velocity-dependent characteristics of activa...

  17. Do early quadriceps exercises affect the outcome of ACL reconstruction? A randomised controlled trial.

    Science.gov (United States)

    Shaw, Triston; Williams, Marie T; Chipchase, Lucy S

    2005-01-01

    A prospective, blinded, randomised controlled trial investigated the effectiveness of quadriceps exercises following anterior cruciate ligament reconstruction. A treatment group (Quadriceps exercise group) performed straight leg raises and isometric quadriceps contractions throughout the first two postoperative weeks, and a second group (No quadriceps exercise group) did not. A battery of outcome measures assessed subjects postoperatively at day one, two weeks, and one, three and six months. A total of 103 patients (Quadriceps exercise n = 48, No quadriceps exercise n = 55) commenced the study with 91 subjects available at final follow up (Quadriceps exercise n = 47, No quadriceps exercise n = 44). Performance of quadriceps exercises significantly improved a number of knee flexion and extension range of motion measurements (p = 0.01 to 0.04). No significant differences were found between the two groups at any postoperative period for quadriceps lag (p = 0.36), functional hop testing (p = 0.49 to 0.51), isokinetic quadriceps strength (p = 0.70 to 0.72), the majority of numerical analogue scores (p = 0.1 to 0.94) and Cincinnati scores (p = 0.10 to 0.84). Subjects performing quadriceps exercises reported significantly higher pain scores with exercise on the first postoperative day (p = 0.02). At six months postoperatively, the Quadriceps exercise subjects reported significantly more favourable Cincinnati scores for symptoms (p = 0.005) and problems with sport (p = 0.05). While average knee laxity was not significantly different between treatment groups over time (p = 0.27 to 0.94), quadriceps exercise performance was associated with a significantly lower incidence of abnormal knee laxity. Isometric quadriceps exercises and straight leg raises can be safely prescribed during the first two postoperative weeks and confer advantages for faster recovery of knee range of motion and stability. It remains to be proven whether the magnitude of differences between groups is

  18. THE EFFECTS OF KNEE JOINT EFFUSION ON QUADRICEPS ELECTROMYOGRAPHY DURING JOGGING

    Directory of Open Access Journals (Sweden)

    William I. Sterett

    2005-03-01

    Full Text Available To investigate and describe the influence of intra-articular effusion on knee joint kinematics and electromyographic (EMG profiles during jogging. Thirteen individuals underwent a 20 cc 0.9% saline insufflation of the knee joint capsule and completed 8 jogging trials. Stance phase, sagittal plane knee joint kinematics and thigh muscular EMG profiles were compared pre- and post-insufflation utilizing a paired t-test (p = 0.05. Mild knee effusion caused a reduction in vastus medialis (p = 0.005 and lateralis (p = 0.006 EMG activity. The rectus femoris, biceps femoris and medial hamstring muscles did not exhibit changes due to this protocol. There were no changes in the sagittal plane knee joint kinematic pattern. Twenty cc effusion can cause quadriceps inhibition in the vastus medialis and the vastus lateralis in otherwise healthy individuals during jogging. This study provides baseline data for the effects of mild knee joint effusion on thigh musculature during jogging.

  19. Adductor Canal Block versus Femoral Nerve Block and Quadriceps Strength

    DEFF Research Database (Denmark)

    Jæger, Pia Therese; Nielsen, Zbigniew Jerzy Koscielniak; Henningsen, Lene Marianne;

    2013-01-01

    : The authors hypothesized that the adductor canal block (ACB), a predominant sensory blockade, reduces quadriceps strength compared with placebo (primary endpoint, area under the curve, 0.5-6 h), but less than the femoral nerve block (FNB; secondary endpoint). Other secondary endpoints were...

  20. The determination of isokinetic performance values of knee joint and Hamstring (flexor/Quadriceps (extensor ratios differences in Volleyball players’

    Directory of Open Access Journals (Sweden)

    Özlem Yenigün

    2008-06-01

    Full Text Available The aim of this study was to determined the values of isokinetic performance in knee joint and the ratios of hamstring/quadriceps (H/Q between volleyball players and controls. 30 male volleyball players (age: 19,46±2,1 and 30 male controls (age: 19,66±2,0 were participated in this study. This study investigated hamstring and quadriceps muscles strength ratio obtained during concentric muscle contraction. The ratio of H/Q muscle strength which was an indicator of normal balance between the knee flexors and extensor and it is important to estimate of the capacity for stabilization of knee joint and the preventation of disability. Knee flexion and extension measurements were tested on biodex system–3 dynamometer in %60, %180 and %300 deg/sec test protocols. The range of motion of knee Joint was evaluated by biodex system–3 dynamometer. There was no statistical difference in the ROM of the knee joint between volleyball players and controls (p>0,05. The isokinetic values of volleyball players were significantly higher than controls (p<0,05. H/Q values must be determined to prevent disability. For the aim of get ready for the season and supply the continuity of performance level increases, preseason isokinetic testing of athletes may be helpful to test for strength imbalance and to determine the correct exercises which is suitable for remove the H/Q disproportion.

  1. Muscle breakdown and repair in polymyositis: a case study.

    Science.gov (United States)

    Edwards, R H; Wiles, C M; Round, J M; Jackson, M J; Young, A

    1979-01-01

    Muscle breakdown and repair were measured by metabolic balance techniques in a patient with polymyositis who was being treated with prednisolone and azathioprine. Changes in body muscle mass that had been estimated from nitrogen and phosphorus balances correlated with antropometric assessments of thigh muscle mass and quadriceps strength. Decline in muscle strength was associated with a net rate of muscle breakdown of 148 g/day. Recovery was associated with a net rate of muscle repair of up to 100 g/day. Early reduction in corticosteroid treatment appeared to enhance the rate of repair. Changes in the isometric contraction force of the quadriceps muscle (but not in clinical symptoms, plasma creatine kinase [CK] or erythrocyte sedimentation rate [ESR] were found to reliably indicate whether the muscle was in a state of breakdown or repair. Treatment of the individual patient may be quantitatively monitored by metabolic balance studies or, more simply, by measurement of muscle strength.

  2. Nitric oxide and voluntary exercise together promote quadriceps hypertrophy and increase vascular density in female 18-mo-old mice.

    Science.gov (United States)

    Leiter, Jeff R S; Upadhaya, Ritika; Anderson, Judy E

    2012-05-01

    Age-related sarcopenia reduces the size, strength, and function of muscle, and the diameter of muscle fibers. It also disrupts the dystrophin-glycoprotein complex, dislocating nitric oxide synthase 1 (NOS-1) and reducing sarcolemmal integrity. This study of quadriceps muscle in 18-mo-old mice showed that NO-donor treatment with isosorbide dinitrate (I) for 6 wk, in combination with voluntary exercise for 3 wk, increased muscle mass by 25% and stimulated cell proliferation. The resulting fiber hypertrophy was accompanied by a lower ratio of protein:DNA, consistent with myogenic-cell hyperplasia. Treatment enhanced the ratio of NOS-1:β-dystroglycan in correlation with fiber diameter, improved sarcolemmal integrity, and increased vascular density after an increase in vascular endothelial growth factor protein at 3 wk. Results demonstrate that age-related muscle refractoriness to exercise can be overcome with NO-donor treatment. Since activation of muscle stem cells and vascular perfusion are limiting factors in the maintenance, regeneration, and growth of aged muscle, results suggest the feasibility of using NO-donor drugs to combat atrophy and muscle ischemia. Improved function and quality of life from the NO-amplified effects of exercise may be useful in aging and other conditions such as disuse, insulin resistance, or microgravity.

  3. Dry needling: Effects on activation and passive mechanical properties of the quadriceps, pain and range during late stage rehabilitation of ACL reconstructed patients.

    Science.gov (United States)

    Ortega-Cebrian, Silvia; Luchini, Nicolleta; Whiteley, Rodney

    2016-09-01

    Dry needling (DN) is reported to decrease pain and improve functional movements yet the mechanisms remain unclear. Changes in muscle tone and other mechanical properties after DN could contribute to these findings but have not been investigated. Examine EMG and passive mechanical properties of the quadriceps muscle before and after DN. EMG, MyotonPro and clinical measurements were taken pre and post DN. Rehabilitation department at Aspetar Sports Medicine Hospital, Qatar. 20 subjects reporting pain and quadriceps muscle tension. Pain (VAS, measured during a single leg step down), knee flexion range, and passive mechanical properties of the superficial quadriceps were measured using the MyotonPro device. Pain decreased (p  0.11, ES = 0.13). Passive mechanical properties were not significantly different in rectus femoris (RF) and VL. Decrement and Resistance of the Vastus Medialis (VM) were significantly decreased (p0.19). DN resulted in small reductions in: pain, resting activation (EMG of VL), decrement and resistance (of VM). Copyright © 2016 Elsevier Ltd. All rights reserved.

  4. Effect of transcutaneous electrical muscle stimulation on postoperative muscle mass and protein synthesis

    DEFF Research Database (Denmark)

    Vinge, O; Edvardsen, L; Jensen, F

    1996-01-01

    In an experimental study, 13 patients undergoing major elective abdominal surgery were given postoperative transcutaneous electrical muscle stimulation (TEMS) to the quadriceps femoris muscle on one leg; the opposite leg served as control. Changes in cross-sectional area (CSA) and muscle protein...... muscle protein synthesis and muscle mass after abdominal surgery and should be evaluated in other catabolic states with muscle wasting....... synthesis were assessed by computed tomography and ribosome analysis of percutaneous muscle biopsies before surgery and on the sixth postoperative day. The percentage of polyribosomes in the ribosome suspension decreased significantly (P

  5. Efeitos na medida do ângulo Q com a contração isométrica voluntária máxima do músculo quadricipital Efectos en la medida del ángulo Q con la contracción isométrica voluntária máxima del musculo cuadricipital Effects in the Q angle measurement with maximal voluntary isometric contraction of the quadriceps muscle

    Directory of Open Access Journals (Sweden)

    A.C.G. Belchior

    2006-02-01

    examination situations, having the quadriceps relaxed and in a maximal voluntary isometric contraction (MVIC through radiographic measurement, aiming to contribute to the assessment and treatment of patients with patelofemoral disorder (PFD. Through the standard radiological method twenty 21 years old mean women (40 knees were assessed. All individuals were positioned supine using a U-podalic stabilizer, having their lower limbs relaxed, using a plumb film on the anterior tuberosity of the tibia. For the statistical analysis, the averages for the asymptomatic and symptomatic groups in a relaxed and MVIC status, as well as the Student's t-test with p < 0.05 significance level were used. The mean values to the Q angle compared to the asymptomatic group were 17.15º on relaxation, and 14.5º on MVIC, while the asymptomatic group presented 21.45º, and 15.8º, respectively. The results in the equality analysis between the symptomatic and asymptomatic groups on the relaxed status attained a p = 0.004, and to the maximal voluntary isometric contraction, p = 0.29. Considering the data attained in the present study, it can be verified that in a relaxing status, there is a difference between the value of the Q angle among symptomatic and asymptomatic individuals, being found a higher value in the FPD bearers, while in a maximal isometric contraction of the quadriceps muscle no statistical difference was found in the present study, with a reduction in the angle in both groups.

  6. Angle-specific hamstring-to-quadriceps ratio: a comparison of football players and recreationally active males.

    Science.gov (United States)

    Evangelidis, Pavlos Eleftherios; Pain, Matthew Thomas Gerard; Folland, Jonathan

    2015-01-01

    It is currently unclear how football participation affects knee-joint muscle balance, which is widely considered a risk factor for hamstrings injury. This study compared the angle-specific functional hamstring-to-quadriceps (H:Q) ratio (hamstrings eccentric torque as a ratio of quadriceps concentric torque at the same knee-joint angle) of football players with recreationally active controls. Ten male footballers and 14 controls performed maximal voluntary isometric and isovelocity concentric and eccentric contractions (60, 240 and 400° s(-1)) of the knee extensors and flexors. Gaussian fitting to the raw torque values was used to interpolate torque values for knee-joint angles of 100-160° (60° s(-1)), 105-160° (240° s(-1)) and 115-145° (400° s(-1)). The angle-specific functional H:Q ratio was calculated from the knee flexors eccentric and knee extensors concentric torque at the same velocity and angle. No differences were found for the angle-specific functional H:Q ratio between groups, at any velocity. Quadriceps and hamstrings strength relative to body mass of footballers and controls was similar for all velocities, except concentric knee flexor strength at 400° s(-1) (footballers +40%; P < 0.01). In previously uninjured football players, there was no intrinsic muscle imbalance and therefore the high rate of hamstring injuries seen in this sport may be due to other risk factors and/or simply regular exposure to a high-risk activity.

  7. Quadriceps tendon injuries in national football league players.

    Science.gov (United States)

    Boublik, Martin; Schlegel, Theodore F; Koonce, Ryan C; Genuario, James W; Kinkartz, Jason D

    2013-08-01

    Distal quadriceps tendon tears are uncommon injuries that typically occur in patients older than 40 years of age, and they have a guarded prognosis. Predisposing factors, prodromal findings, mechanisms of injury, treatment guidelines, and recovery expectations are not well described in high-level athletes. Professional American football players with an isolated tear of the quadriceps tendon treated with timely surgical repair will return to their sport. Case series; Level of evidence, 4. Fourteen unilateral distal quadriceps tendon tears were identified in National Football League (NFL) players from 1994 to 2004. Team physicians retrospectively reviewed training room and clinic records, operative notes, and imaging studies for each of these players. Data on each player were analyzed to identify variables predicting return to play. A successful outcome was defined as returning to play in regular-season NFL games. Eccentric contraction of the quadriceps was the most common mechanism of injury, occurring in 10 players. Only 1 player had antecedent ipsilateral extensor mechanism symptoms. Eleven players had a complete rupture of the quadriceps tendon, and 3 had partial tears. There were no associated knee injuries. All ruptures were treated with surgical repair, 1 of which was delayed after failure of nonoperative treatment. Fifty percent of players returned to play in regular-season NFL games. There was a trend toward earlier draft status for those who returned to play compared with those who did not (draft round, 3.1 ± 2.5 vs. 6.0 ± 2.9, respectively; P = .073). For those who returned to play, the average number of games after injury was 40.9 (range, 12-92). Quadriceps tendon tears are rare in professional American football players, and they usually occur from eccentric load on the extensor mechanism. Prodromal symptoms and predisposing factors are usually absent. Even with timely surgical repair, there is a low rate of return to play in regular-season games. There

  8. Neuromuscular electrical stimulation of the quadriceps in patients with non-small cell lung cancer receiving palliative chemotherapy: a randomized phase II study.

    Directory of Open Access Journals (Sweden)

    Matthew Maddocks

    Full Text Available A reduced exercise capacity is associated with increased morbidity and mortality in patients with advanced non-small cell lung cancer (NSCLC. Therapeutic exercise can be beneficial and neuromuscular electrical stimulation (NMES of the quadriceps muscles may represent a practical approach. The primary aim of this study was to determine the acceptability of NMES of the quadriceps to patients with NSCLC used alongside palliative chemotherapy. Secondary aims explored aspects of safety and efficacy of NMES in this setting.Patients with advanced NSCLC due to receive first-line palliative chemotherapy were randomized to usual care with or without NMES. They were asked to undertake 30 minute sessions of NMES, ideally daily, but as a minimum, three times weekly. For NMES to be considered acceptable, it was predetermined that ≥80% of patients should achieve this minimum level of adherence. Qualitative interviews were held with a subset of patients to explore factors influencing adherence. Safety was assessed according to the Common Terminology Criteria for Adverse Events. Quadriceps muscle strength, thigh lean mass, and physical activity level were assessed at baseline and after three cycles of chemotherapy.49 patients (28 male, median (IQR age 69 (64-75 years participated. Of 30 randomized to NMES, 18 were eligible for the primary endpoint, of whom 9 (50% [90% CI, 29 to 71] met the minimum level of adherence. Adherence was enhanced by incorporating sessions into a daily routine and hindered by undesirable effects of chemotherapy. There were no serious adverse events related to NMES, nor significant differences in quadriceps muscle strength, thigh lean mass or physical activity level between groups.NMES is not acceptable in this setting, nor was there a suggestion of benefit. The need remains to explore NMES in patients with cancer in other settings.Current Controlled Trials ISRCTN 42944026 www.controlled-trials.com/ISRCTN42944026.

  9. The spectrum of familial inclusion body myopathies in 13 families and a description of a quadriceps-sparing phenotype in non-Iranian Jews.

    Science.gov (United States)

    Sivakumar, K; Dalakas, M C

    1996-10-01

    The frequency, patterns of inheritance and clinical phenotypes of inherited myopathies with histologic features of rimmed vacuoles, tubulofilamentous inclusions and absence of inflammation (familial and hereditary inclusion body myopathy [f-IBM]) are poorly defined. Quadriceps sparing is a characteristic of f-IBM seen in the Iranian Jewish population. Among 101 patients with the feature of a red-rimmed vacuolar myopathy, characterized as inclusion body myopathy, seen during the last 4 years, we identified 13 families with f-IBM (12.8% frequency when one member per family was considered). Five families had an autosomal dominant and eight had an autosomal recessive form of inheritance. Among the latter group, five patients with early-onset disease (two Caucasian Americans, an Asian Indian, and two unrelated Iranian Jews) had the distinct feature of quadriceps sparing, which was confirmed by MRI of the thighs. Their disease began with weakness and strophy of the foot extensors, forearm flexors, and first dorsal interossei muscles and progressed to the forearm flexors, girdle, and axial muscles, but spared the quadriceps. Serum CK was normal. Muscle biopsies showed rimmed vacuoles, small fibers in groups, amyloid deposition (in one patient), tubulofilaments, and no inflammation. Immunocytochemistry did not reveal abnormalities of various membrane or cytoskeletal proteins. Major histocompatibility complex (MHC) class I antigen was expressed only in a few degenerating fibers invaded by macrophages. T-cell infiltrates were not present. We conclude that in a large referral population, dominant and recessive hereditary and familial forms of IBM are not rare. Quadriceps-sparing myopathy appears to be a clinically distinct, autosomal recessive, nonimmune, distal vacuolar myopathy that is not limited to Iranian-Jewish ethnic groups.

  10. GH administration changes myosin heavy chain isoforms in skeletal muscle but does not augment muscle strength or hypertrophy, either alone or combined with resistance exercise training in healthy elderly men

    DEFF Research Database (Denmark)

    Lange, Kai Henrik Wiborg; Andersen, Jesper Løvind; Beyer, Nina

    2002-01-01

    GH administration, either alone or combined with resistance exercise training (RT), has attracted interest as a means of increasing muscle mass and strength in the elderly. In the present study, 31 healthy, elderly men [age, 74 +/- 1 yr (mean +/- SEM)] were assigned to either RT [3 sessions/wk, 3......-5 sets of 8-12 repetition maximum (RM)/session] + placebo (n = 8), RT + GH (n = 8), GH (n = 8), or placebo (n = 7) in a randomized, placebo-controlled, double-blinded (RT + placebo and RT + GH) or single-blinded (GH or placebo) design. Measurements of: 1) isokinetic quadriceps muscle strength; 2......) quadriceps muscle power; 3) quadriceps muscle fiber type, size, and myosin heavy chain (MHC) composition; 4) quadriceps cross-sectional area (CSA) [nuclear magnetic resonance imaging (NMRI)]; 5) body composition (dual-energy x-ray absorptiometry scanning); and 6) GH-related serum markers were performed...

  11. Clinical outcomes after repair of quadriceps tendon rupture: a systematic review.

    Science.gov (United States)

    Ciriello, Vincenzo; Gudipati, Suribabu; Tosounidis, Theodoros; Soucacos, P N; Giannoudis, Peter V

    2012-11-01

    The existing evidence regarding the management of quadriceps tendon rupture remains obscure. The aim of the current review is to investigate the characteristics, the different techniques employed and to analyse the clinical outcomes following surgical repair of quadriceps tendon rupture. An Internet based search of the English literature of the last 25 years was carried out. Case reports and non-clinical studies were excluded. The methodological quality of the included studies was assessed using the Coleman Methodology Score. All data regarding mechanism and site of rupture, type of treatment, time elapsed between diagnosis and repair, patients' satisfaction, clinical outcome, return to pre-injury activities, complications and recurrence rates were extracted and analysed. Out of 474 studies identified, 12 met the inclusion criteria. The average of Coleman Methodology Score was 50.46/100. In total 319 patients were analysed with a mean age of 57 years (16-85). The mean time of follow-up was 47.5 months (3 months to 24 years). The most common mechanism of injury was simple fall (61.5%). Spontaneous ruptures were reported in 3.2% of cases. The most common sites of tear were noted between 1cm and 2 cm of the superior pole of the patella and, in the older people, at the osseotendinous junction. The most frequently used repair technique was patella drill holes (50% of patients). Simple sutures were used in mid-substance ruptures. Several reinforcement techniques were employed in case of poor quality or retraction of the torn ends of tendon. The affected limb was immobilised in a cast for a period of 3-10 weeks. Quadriceps muscular atrophy and muscle strength deficit were present in most of the cases. Worst results were noted in delayed repairs. Reported complications included heterotopic ossifications in 6.9% of patients, deep venous thrombosis or pulmonary embolism in 2.5%, superficial infection in 1.2% and deep infection in 1.1%. It appears that the type of surgical

  12. Effect of 3 Different Applications of Kinesio Taping Denko® on Electromyographic Activity: Inhibition or Facilitation of the Quadriceps of Males During Squat Exercise.

    Science.gov (United States)

    Serrão, Júlio C; Mezêncio, Bruno; Claudino, João G; Soncin, Rafael; Miyashiro, Pedro L Sampaio; Sousa, Eric P; Borges, Eduardo; Zanetti, Vinícius; Phillip, Igor; Mochizuki, Luiz; Amadio, Alberto C

    2016-09-01

    Kinesio taping consists of a technique which uses the application of an elastic adhesive tape. It has become a widely used rehabilitation modality for the prevention and treatment of musculoskeletal disorders. The objective of this study was to verify the effect of the application of Kinesio Taping Denko(®) in three conditions (facilitation, inhibition, and placebo) on the electromyographic activity of the quadriceps and hamstrings muscles on facilitating or inhibiting the muscle function and on the perceived exertion during the barbell back squat exercise in healthy male subjects.

  13. Synthetic Mesh Augmentation of Acute and Subacute Quadriceps Tendon Repair.

    Science.gov (United States)

    Morrey, Matthew C; Barlow, Jonathan D; Abdel, Matthew P; Hanssen, Arlen D

    2016-01-01

    Quadriceps tendon rupture is an uncommon injury. To date, surgical results have been less than favorable. A novel repair technique that uses Marlex mesh (C R Bard, Murray Hill, New Jersey) has been developed. Use of this repair may allow earlier range of motion and functional restoration of extension. The authors sought to evaluate the technical feasibility, durability, and postoperative function of this repair. This study retrospectively analyzed 8 knees (7 patients) operated on with this technique from 1990 to 2011. Mean follow-up was 9 years. Average age at the time of injury was 69 years. Mean operative time was 130 minutes. No perioperative complications occurred, no patients had clinical evidence of failure, and no patients required subsequent reoperation. Mean flexion at final follow-up was 100°. Of the 8 knees, 7 knees had no extensor lag at final follow-up. Marlex mesh augmentation for quadriceps tendon ruptures has promising clinical results, despite significant comorbidities. The results showed that the technique was feasible, with low cost and reasonable operative time. The clinical results were durable, with no intraoperative complications, no re-ruptures, rare extension lag, and good range of motion. Therefore, synthetic mesh augmentation is a feasible option in acute quadriceps tendon ruptures.

  14. Pathology of skeletal muscle in fibromyalgia

    DEFF Research Database (Denmark)

    Drewes, A M; Andreasen, A; Schrøder, H D

    1993-01-01

    The value of muscle biopsy in fibromyalgia is still questioned. In this study we obtained 50 quadriceps biopsies from 20 patients and compared them blindly to 10 biopsies from five normal controls. Using light microscopy, histochemical and immunoenzymatic methods we found no definite evidence...

  15. Acute hypoxia limits endurance but does not affect muscle contractile properties.

    NARCIS (Netherlands)

    Degens, H.; Sanchez Horneros, J.M.; Hopman, M.T.E.

    2006-01-01

    Acute hypoxia causes skeletal muscle dysfunction in vitro, but little is known about its effect on muscle function in vivo. In 10 healthy male subjects, isometric contractile properties and fatigue resistance of the quadriceps muscle were determined during normoxia and hypoxia using electrically evo

  16. Expiratory muscle loading increases intercostal muscle blood flow during leg exercise in healthy humans

    Science.gov (United States)

    Athanasopoulos, Dimitris; Louvaris, Zafeiris; Cherouveim, Evgenia; Andrianopoulos, Vasilis; Roussos, Charis; Zakynthinos, Spyros

    2010-01-01

    We investigated whether expiratory muscle loading induced by the application of expiratory flow limitation (EFL) during exercise in healthy subjects causes a reduction in quadriceps muscle blood flow in favor of the blood flow to the intercostal muscles. We hypothesized that, during exercise with EFL quadriceps muscle blood flow would be reduced, whereas intercostal muscle blood flow would be increased compared with exercise without EFL. We initially performed an incremental exercise test on eight healthy male subjects with a Starling resistor in the expiratory line limiting expiratory flow to ∼ 1 l/s to determine peak EFL exercise workload. On a different day, two constant-load exercise trials were performed in a balanced ordering sequence, during which subjects exercised with or without EFL at peak EFL exercise workload for 6 min. Intercostal (probe over the 7th intercostal space) and vastus lateralis muscle blood flow index (BFI) was calculated by near-infrared spectroscopy using indocyanine green, whereas cardiac output (CO) was measured by an impedance cardiography technique. At exercise termination, CO and stroke volume were not significantly different during exercise, with or without EFL (CO: 16.5 vs. 15.2 l/min, stroke volume: 104 vs. 107 ml/beat). Quadriceps muscle BFI during exercise with EFL (5.4 nM/s) was significantly (P = 0.043) lower compared with exercise without EFL (7.6 nM/s), whereas intercostal muscle BFI during exercise with EFL (3.5 nM/s) was significantly (P = 0.021) greater compared with that recorded during control exercise (0.4 nM/s). In conclusion, increased respiratory muscle loading during exercise in healthy humans causes an increase in blood flow to the intercostal muscles and a concomitant decrease in quadriceps muscle blood flow. PMID:20507965

  17. Torque and mechanomyogram relationships during electrically-evoked isometric quadriceps contractions in persons with spinal cord injury.

    Science.gov (United States)

    Ibitoye, Morufu Olusola; Hamzaid, Nur Azah; Hasnan, Nazirah; Abdul Wahab, Ahmad Khairi; Islam, Md Anamul; Kean, Victor S P; Davis, Glen M

    2016-08-01

    The interaction between muscle contractions and joint loading produces torques necessary for movements during activities of daily living. However, during neuromuscular electrical stimulation (NMES)-evoked contractions in persons with spinal cord injury (SCI), a simple and reliable proxy of torque at the muscle level has been minimally investigated. Thus, the purpose of this study was to investigate the relationships between muscle mechanomyographic (MMG) characteristics and NMES-evoked isometric quadriceps torques in persons with motor complete SCI. Six SCI participants with lesion levels below C4 [(mean (SD) age, 39.2 (7.9) year; stature, 1.71 (0.05) m; and body mass, 69.3 (12.9) kg)] performed randomly ordered NMES-evoked isometric leg muscle contractions at 30°, 60° and 90° knee flexion angles on an isokinetic dynamometer. MMG signals were detected by an accelerometer-based vibromyographic sensor placed over the belly of rectus femoris muscle. The relationship between MMG root mean square (MMG-RMS) and NMES-evoked torque revealed a very high association (R(2)=0.91 at 30°; R(2)=0.98 at 60°; and R(2)=0.97 at 90° knee angles; Pcontractions. The strong positive relationship between MMG signal and NMES-evoked torque production suggested that the MMG might be deployed as a direct proxy for muscle torque or fatigue measurement during leg exercise and functional movements in the SCI population.

  18. Quadriceps neuromuscular function and self-reported functional ability in knee osteoarthritis.

    Science.gov (United States)

    Berger, M J; McKenzie, C A; Chess, D G; Goela, A; Doherty, T J

    2012-07-01

    The purposes of this study were to determine 1) the relationships of self-reported function scores in patients with knee osteoarthritis (OA) to both maximal isometric torque and to isotonic power at a variety of loads, and 2) the degree to which muscle volume (MV) or voluntary activation (VA) are associated with torque and power measures in this population. Isometric maximal voluntary contraction (MVC) torque and isotonic power [performed at loads corresponding to 10, 20, 30, 40, and 50% MVC, and a minimal load ("Zero Load")] were measured in 40 participants with knee OA. Functional ability was measured with the Western Ontario and McMaster Osteoarthritis Index (WOMAC) function subscale. MV was determined with magnetic resonance imaging, and VA was measured with the interpolated twitch technique. In general, power measured at lower loads (Zero Load and 10-30% MVC, r(2) = 0.21-0.28, P MVC torque (r(2) = 0.18, P MVC torque and power measures in multiple regression models (r(2) = 0.42-0.72). VA explained only 6% of the variance in MVC torque and was not significantly associated with power at any load (P > 0.05). Quadriceps MVC torque and power are associated with self-reported function in knee OA, but muscle power at lower loads is more predictive of function than MVC torque. The variance in MVC torque and power between participants is due predominantly to differences in MV and has little to do with deficits in VA.

  19. Effects of Neuromuscular Fatigue on Quadriceps Strength and Activation and Knee Biomechanics in Individuals post Anterior Cruciate Ligament Reconstruction and Healthy Adults

    Science.gov (United States)

    Thomas, Abbey C.; Lepley, Lindsey K.; Wojtys, Edward M.; McLean, Scott G.; Palmieri-Smith, Riann M.

    2016-01-01

    Study design Laboratory based experiment using a pre/post-test design. Objectives To determine the effects of neuromuscular fatigue on quadriceps strength and activation and sagittal and frontal plane knee biomechanics during dynamic landing following anterior cruciate ligament reconstruction (ACLr). Background Impaired quadriceps central activation occurs post-ACLr, likely altering lower extremity biomechanics. Neuromuscular fatigue similarly reduces volitional muscle activation and impairs neuromuscular control. Upon return to full activity post-ACLr, individuals likely concurrently experience quadriceps central activation deficits and neuromuscular fatigue, though the effects of fatigue on muscle strength and activation and biomechanics post-ACLr are unknown. Methods Seventeen individuals 7–10 months post-ACLr and 16 controls participated. Quadriceps strength and central activation ratio were recorded pre-/post-fatigue, which was induced via sets of double-leg squats. Knee biomechanics were recorded during a dynamic landing activity pre-/post-fatigue. Results Both groups demonstrated smaller knee flexion (initial contact:P=.017; peak:P=.004) and abduction (initial contact:P=.005; peak:P=.009) angles post-fatigue. The ACLr group had smaller peak knee flexion angles (PKnee flexion moment was smaller in ACLr than controls pre- (Pknee flexion moments post-fatigue (P=.001). Knee abduction moment was smaller in both groups post-fatigue (P=.003). All participants demonstrated significantly lower strength (Pbiomechanics presented post-fatigue in both groups, confirming that neuromuscular fatigue may increase non-contact ACL injury risk. However, these changes were not exaggerated in ACLr participants, likely because they already demonstrated a stiff-legged landing strategy pre-fatigue. PMID:26471851

  20. Suture anchor repair of quadriceps tendon rupture after total knee arthroplasty.

    Science.gov (United States)

    Kim, Tae Won B; Kamath, Atul F; Israelite, Craig L

    2011-08-01

    Disruption of the extensor mechanism after total knee arthroplasty (TKA) is a devastating complication, usually requiring surgical repair. Although suture anchor fixation is well described for repair of the ruptured native knee quadriceps tendon, no study has discussed the use of suture anchors in quadriceps repair after TKA. We present an illustrative case of successful suture anchor fixation of the quadriceps mechanism after TKA. The procedure has been performed in a total of 3 patients. A surgical technique and brief review of the literature follows. Suture anchor fixation of the quadriceps tendon is a viable option in the setting of rupture after TKA.

  1. Index of fatigue quadriceps in soccer athletes after anterior cruciate ligament reconstruction

    Directory of Open Access Journals (Sweden)

    Maria Luzete Costa Cavalcante

    Full Text Available ABSTRACT OBJECTIVE: The present study aimed to evaluate the muscle fatigue of the quadriceps muscle in high-performance soccer players undergoing (anterior cruciate ligament ACL reconstruction. METHODS: We evaluated 17 high-performance soccer players from three professional soccer teams of a state in Brazil from August 2011 to July 2012. All subjects were evaluated between 5.5 and 7 months after ACL reconstruction with a Biodex(r isokinetic dynamometer (System 4 Pro with test protocol CON/CON at 60°/s and 300°/s with 5 and 15 repetitions, respectively. In the calculation of local muscle fatigue, the fatigue index was used, which is calculated by dividing the labor done in the first one-third of the repetitions by that done at the final one-third of the repetitions, and multiplying by 100 to express a unit in percentage (i.e., as a discrete quantitative variable. RESULTS: All subjects were male, with a mean age of 21.3 ± 4.4 years and mean BMI 23.4 ± 1.53 cm; left dominance was observed in 47% (n = 8 of athletes, and right dominance, in 53% (n = 9 of athletes; and the limb involved in the lesion was the dominant in 29% (n = 5 and the non-dominant in 71% (n = 12. Fatigue rates were 19.6% in the involved limb and 29.0% in the non-involved limb. CONCLUSION: The results allow us to conclude that there was no significant difference between the limbs involved and not in ACL injuries regarding local muscle fatigue. No association was observed between the dominant side and the limb involved in the ACL injury.

  2. Simultaneous bilateral quadriceps tendon rupture in a patient on chronic haemodialysis. (Short-term results of treatment with transpatellar sutures augmented with a quadriceps tendon flap).

    Science.gov (United States)

    Kayali, Cemil; Agus, Haluk; Turgut, Ali; Taskiran, Can

    2008-01-01

    Quadriceps tendon ruptures are rare orthopaedic injuries. Although they are generally seen after the age of 50, they may occur in younger patients with certain underlying conditions, including chronic haemodialysis. Several repair techniques have been proposed but the choice of the best method is still a matter of controversy. This paper presents the case of a renal failure patient with 10 years' history of haemodialysis treatment suffering from bilateral quadriceps tendon rupture. The treatment was with transpatellar sutures augmented with a reverse quadriceps tendon flap. His short-term clinical and radiological results are satisfactory.

  3. Comparison of neuromuscular and quadriceps strengthening exercise in the treatment of varus malaligned knees with medial knee osteoarthritis: a randomised controlled trial protocol

    Directory of Open Access Journals (Sweden)

    Bennell Kim L

    2011-12-01

    Full Text Available Abstract Background Osteoarthritis of the knee involving predominantly the medial tibiofemoral compartment is common in older people, giving rise to pain and loss of function. Many people experience progressive worsening of the disease over time, particularly those with varus malalignment and increased medial knee joint load. Therefore, interventions that can reduce excessive medial knee loading may be beneficial in reducing the risk of structural progression. Traditional quadriceps strengthening can improve pain and function in people with knee osteoarthritis but does not appear to reduce medial knee load. A neuromuscular exercise program, emphasising optimal alignment of the trunk and lower limb joints relative to one another, as well as quality of movement performance, while dynamically and functionally strengthening the lower limb muscles, may be able to reduce medial knee load. Such a program may also be superior to traditional quadriceps strengthening with respect to improved pain and physical function because of the functional and dynamic nature. This randomised controlled trial will investigate the effect of a neuromuscular exercise program on medial knee joint loading, pain and function in individuals with medial knee joint osteoarthritis. We hypothesise that the neuromuscular program will reduce medial knee load as well as pain and functional limitations to a greater extent than a traditional quadriceps strengthening program. Methods/Design 100 people with medial knee pain, radiographic medial compartment osteoarthritis and varus malalignment will be recruited and randomly allocated to one of two 12-week exercise programs: quadriceps strengthening or neuromuscular exercise. Each program will involve 14 supervised exercise sessions with a physiotherapist plus four unsupervised sessions per week at home. The primary outcomes are medial knee load during walking (the peak external knee adduction moment from 3D gait analysis, pain, and self

  4. Hamstring transfer for quadriceps paralysis in post polio residual paralysis

    Directory of Open Access Journals (Sweden)

    Jagadish J Patwa

    2012-01-01

    Conclusions: H to Q transfer in the presence of quadriceps paralysis with good power in hamstring is a better alternative than supracondylar osteotomy because it is a dynamic correction and it produces some degree of recurvatum with increasing stability of knee in extension while walking. While inserting hamstring over patella the periosteum is not cut in an I-shaped fashion to create a flap which gives additional strength to new insertion and also patella act as a fulcrum during the extension of knee by producing the bowstring effect.

  5. Relationship between functional hamstring: quadriceps ratios and running economy in highly trained and recreational female runners.

    Science.gov (United States)

    Sundby, Oyvind H; Gorelick, Mark L S

    2014-08-01

    The purpose of this study was to investigate the relationship between running economy (RE), functional hamstring:quadriceps peak torque ratios (f-H:Q), and flexibility among female runners. Seven highly trained (HT) female runners (age: 25.7 ± 4.7 years, VO2peak of 62.0 ± 4.8 ml·kg-1·min-1) and 11 recreational female runners (age of 28.8 ± 5.6 years, VO2peak of 49.2 ± 4.6 ml·kg-1·min-1) were measured for maximal aerobic power (VO2peak), RE, heart rate, respiratory exchange ratio, f-H:Q (Hecc:Qcon and Hcon:Qecc), and sit-and-reach hamstring/trunk flexibility. On 2 separate days, RE was measured on a treadmill at 1% grade at 2 velocities (160.9 and 201.2 m·min-1) for 6 minutes each, and isokinetic knee strength was measured at 3 angular velocities (60, 120, and 180°·s-1) for both concentric and eccentric muscle actions. The unpaired t-tests showed a consistent trend toward higher f-H:Q ratios at all angular velocities among the HT runners. Highly trained runners had significantly higher Hecc:Qcon at 120°·s-1 (p ≤ 0.05) and 180°·s-1 (p ≤ 0.05). Whole group correlations demonstrated a significant correlation between Hcon:Qecc at 180°·s-1 and RE (ml·kg-1·km-1) at 201.2 m·min-1 (R = -0.48, p ≤ 0.05). No significant relationships were found between flexibility, or hamstring and quadriceps peak torque (N·m) and RE (p > 0.05). This cross-sectional analysis suggests that higher f-H:Q torque ratios, and not muscle strength per se, are associated with a lower metabolic cost of running. Therefore, runners should consider implementing hamstring exercises to improve their f-H:Q ratios.

  6. MUSCLE INJURIES IN ATHLETES.

    Science.gov (United States)

    Barroso, Guilherme Campos; Thiele, Edilson Schwansee

    2011-01-01

    This article had the aim of demonstrating the physiology, diagnosis and treatment of muscle injuries, focusing on athletes and their demands and expectations. Muscle injuries are among the most common complaints in orthopedic practice, occurring both among athletes and among non-athletes. These injuries present a challenge for specialists, due to the slow recovery, during which time athletes are unable to take part in training and competitions, and due to frequent sequelae and recurrences of the injuries. Most muscle injuries (between 10% and 55% of all injuries) occur during sports activities. The muscles most commonly affected are the ischiotibial, quadriceps and gastrocnemius. These muscles go across two joints and are more subject to acceleration and deceleration forces. The treatment for muscle injuries varies from conservative treatment to surgery. New procedures are being used, like the hyperbaric chamber and the use of growth factors. However, there is still a high rate of injury recurrence. Muscle injury continues to be a topic of much controversy. New treatments are being researched and developed, but prevention through muscle strengthening, stretching exercises and muscle balance continues to be the best "treatment".

  7. Bilateral simultaneous quadriceps tendon rupture in a patient with secondary hyperparathyroidism: a case report

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Yeon Soo; Son, Sang Beom; Han, Chang Whan; Kang, Si Won [Taejon St. Mary' s Hospital, The Catholic Univ. of Korea, Taejon (Korea, Republic of)

    2001-11-01

    Simultaneous bilateral rupture of the quadriceps tendon without a significant history of trauma may occur in association with chronic metabolic disorders such as chronic renal failure and secondary hyperparathyroidism, though has rarely been reported. We describe a case of spontaneous bilateral quadriceps tendon rupture in a 36-year-old female patient with secondary hyperparathyroidism.

  8. The use of suture anchors to repair the ruptured quadriceps tendon.

    Science.gov (United States)

    Bushnell, Brandon D; Whitener, George B; Rubright, James H; Creighton, R Alexander; Logel, Kevin J; Wood, Mark L

    2007-07-01

    Quadriceps tendon rupture is an incapacitating injury that usually requires surgical repair. Traditional repair methods involve transpatellar suture tunnels, but recent reports have introduced the idea of using suture anchors to repair the ruptured tendon. We present 5 cases of our technique of using suture anchors to repair the ruptured quadriceps tendon.

  9. Implementation of Open and Closed Kinetic Chain Quadriceps Strengthening Exercises after Anterior Cruciate Ligament Reconstruction.

    Science.gov (United States)

    Ross, Michael D.; Denegar, Craig R.; Winzenried, Jay A.

    2001-01-01

    Reviews the effects of open kinetic chain (OKC) and closed kinetic chain (CKC) exercise on anterior cruciate ligament (ACL) strain and patellofemoral joint stress, suggesting a combination of the two for quadriceps strengthening after ACL reconstruction. Both OKC and CKC exercises may be modified and implemented for quadriceps strengthening after…

  10. Bilateral Simultaneous Quadriceps Tendon Rupture in a 24-Year-Old Obese Patient: A Case Report and Review of the Literature

    Directory of Open Access Journals (Sweden)

    Fahad H. Abduljabbar

    2016-01-01

    Full Text Available Introduction. Simultaneous bilateral quadriceps tendon ruptures (SBQTR are uncommon knee injuries and most frequently occur in male patients, over 50 years of age. It can be associated with one or more predisposing risk factors like obesity, steroids use, and hyperparathyroidism. The main focus of this paper is to review SBQTR in obese patients. Case Report. We are reporting the youngest patient in the literature to date, a 24-year-old obese male patient, who presented to the emergency department complaining of bilateral knee pain and inability to walk after a fall during a basketball game. His clinical examination revealed the presence of a palpable suprapatellar gap and loss of knee extension bilaterally. Magnetic resonance imaging (MRI confirmed that both of his quadriceps tendons were ruptured. A day after his diagnosis, the patient underwent successful operative repair followed by rehabilitation. At the two-year follow-up, the patient had full strength of both quadriceps muscles with no extension lag. Conclusion. The diagnosis of SBQTR can be challenging. Early diagnosis and treatment are associated with better functional outcome compared to delayed treatment. Physicians should have a high index of clinical suspicion in order not to miss such an injury and achieve favourable outcomes.

  11. Bilateral quadriceps tendon rupture: a rare finding in a healthy man after minimal trauma.

    Science.gov (United States)

    Chiu, Michael; Forman, Edward S

    2010-03-01

    Quadriceps tendon rupture is an uncommon injury; the incidence of simultaneous bilateral quadriceps tendon rupture is extremely rare. Two distinct categories-individuals older than 50 years and between 27 and 54 years-have been described. Bilateral quadriceps tendon rupture is more common in patients older than 50 years and is thought to be the result of tendon weakening due to obesity and arteriosclerosis-induced fibrotic changes, or previous injury.In younger individuals, bilateral simultaneous quadriceps rupture is less frequent and has been associated with anabolic steroid use, but more frequently with underlying comorbid medical conditions such as chronic renal failure, hyperparathyroidism, endocrine disorder, gout, diabetes and obesity, which predispose the patients to tendon rupture. Our case report is unique because we report the simultaneous bilateral quadriceps tendon rupture following minor trauma in an otherwise healthy 43-year-old man with no predisposing comorbidity.

  12. Inter-limb differences in quadriceps strength and volitional activation.

    Science.gov (United States)

    Pietrosimone, Brian G; Park, Chang M; Gribble, Phillip A; Pfile, Kate R; Tevald, Michael A

    2012-01-01

    In this crossover study, we wished to determine if normalized inter-limb differences in strength differed from inter-limb differences in voluntary activation at 30°, 70°, and 90° of knee flexion. We also assessed the relationship between inter-limb differences in torque with the inter-limb differences in activation. Twenty-five healthy volunteers were used for final data analyses; the order of leg tested, joint angle, and measurement technique (isokinetic strength, voluntary activation) were randomly assigned. Quadriceps strength was measured isokinetically at 1.05 rad · s(-1), while quadriceps voluntary activation was assessed via the central activation ratio. Absolute values of inter-limb differences for both measures were calculated by subtracting the non-dominant leg values from those of the dominant leg. Inter-limb isokinetic strength differences were greater than inter-limb central activation ratio differences at all joint angles (P = 0.003). Interestingly, inter-limb deficits between measures were not strongly correlated, suggesting that these measurements may be evaluating completely different phenomena within the neuromuscular system. These measurement techniques may provide unique information regarding neuromuscular function, suggesting that researchers and clinicians must utilize information from both techniques to determine the true clinical nature of inter-limb deficits.

  13. Effects of Static and Dynamic Stretching on the Isokinetic Peak Torques and Electromyographic Activities of the Antagonist Muscles

    Science.gov (United States)

    Serefoglu, Abdullah; Sekir, Ufuk; Gür, Hakan; Akova, Bedrettin

    2017-01-01

    The aim of this study was to investigate if static and dynamic stretching exercises of the knee muscles (quadriceps and hamstring muscles) have any effects on concentric and eccentric isokinetic peak torques and electromyographic amplitudes (EMG) of the antagonist muscles. Twenty healthy male athletes (age between 18-30 years) voluntarily participated in this study. All of the subjects visited the laboratory to complete the following intervention in a randomized order on 5 separate days; (a) non-stretching (control), (b) static stretching of the quadriceps muscles, (c) static stretching of the hamstring muscles, (d) dynamic stretching of the quadriceps muscles, and (e) dynamic stretching of the hamstring muscles. Static stretching exercises either for the quadriceps or the hamstring muscles were carried out at the standing and sitting positions. Subjects performed four successive repetitions of each stretching exercises for 30 seconds in both stretching positions. Similar to static stretching exercises two different stretching modes were designed for dynamic stretching exercises. Concentric and eccentric isokinetic peak torque for the non-stretched antagonist quadriceps or hamstring muscles at angular velocities of 60°/sec and 240°/sec and their concurrent electromyographic (EMG) activities were measured before and immediately after the intervention. Isokinetic peak torques of the non-stretched agonist hamstring and quadriceps muscles did not represent any significant (p > 0.05) differences following static and dynamic stretching of the antagonist quadriceps and hamstring muscles, respectively. Similarly, the EMG activities of the agonist muscles exhibited no significant alterations (p > 0.05) following both stretching exercises of the antagonist muscles. According to the results of the present study it is possible to state that antagonist stretching exercises either in the static or dynamic modes do not affect the isokinetic peak torques and the EMG activities

  14. Evidence of O2 supply-dependent VO2 max in the exercise-trained human quadriceps.

    Science.gov (United States)

    Richardson, R S; Grassi, B; Gavin, T P; Haseler, L J; Tagore, K; Roca, J; Wagner, P D

    1999-03-01

    Maximal O2 delivery and O2 uptake (VO2) per 100 g of active muscle mass are far greater during knee extensor (KE) than during cycle exercise: 73 and 60 ml. min-1. 100 g-1 (2.4 kg of muscle) (R. S. Richardson, D. R. Knight, D. C. Poole, S. S. Kurdak, M. C. Hogan, B. Grassi, and P. D. Wagner. Am. J. Physiol. 268 (Heart Circ. Physiol. 37): H1453-H1461, 1995) and 28 and 25 ml. min-1. 100 g-1 (7.5 kg of muscle) (D. R. Knight, W. Schaffartzik, H. J. Guy, R. Predilleto, M. C. Hogan, and P. D. Wagner. J. Appl. Physiol. 75: 2586-2593, 1993), respectively. Although this is evidence of muscle O2 supply dependence in itself, it raises the following question: With such high O2 delivery in KE, are the quadriceps still O2 supply dependent at maximal exercise? To answer this question, seven trained subjects performed maximum KE exercise in hypoxia [0.12 inspired O2 fraction (FIO2)], normoxia (0.21 FIO2), and hyperoxia (1.0 FIO2) in a balanced order. The protocol (after warm-up) was a square wave to a previously determined maximum work rate followed by incremental stages to ensure that a true maximum was achieved under each condition. Direct measures of arterial and venous blood O2 concentration in combination with a thermodilution blood flow technique allowed the determination of O2 delivery and muscle VO2. Maximal O2 delivery increased with inspired O2: 1.3 +/- 0.1, 1.6 +/- 0.2, and 1.9 +/- 0.2 l/min at 0.12, 0.21, and 1.0 FIO2, respectively (P VO2 (VO2 max): 1.04 +/- 0.13, 1. 24 +/- 0.16, and 1.45 +/- 0.19 l/min at 0.12, 0.21, and 1.0 FIO2, respectively (P VO2 max, supporting our previous finding that a decrease in O2 supply will proportionately decrease muscle VO2 max. As even in the isolated quadriceps (where normoxic O2 delivery is the highest recorded in humans) an increase in O2 supply by hyperoxia allows the achievement of a greater VO2 max, we conclude that, in normoxic conditions of isolated KE exercise, KE VO2 max in trained subjects is not limited by mitochondrial

  15. Muscle sonography in six patients with hereditary inclusion body myopathy

    Energy Technology Data Exchange (ETDEWEB)

    Adler, Ronald S. [Weill Medical College of Cornell University, Division of Ultrasound and Body Imaging, Hospital for Special Surgery, New York, NY (United States); Garolfalo, Giovanna [Ospedale Residenza Sanitaria Riabilitativa, Fermo, AP (Italy); Paget, Stephen; Kagen, Lawrence [Weill Medical College of Cornell University, Rheumatology Division, Hospital for Special Surgery, New York, NY (United States)

    2008-01-15

    To evaluate the morphological changes of muscle with sonography in six patients affected by hereditary inclusion body myopathy (HIBM). We studied a group of six Persian Jews diagnosed with HIBM. All were homozygous for the GNE mutation M712T. Ultrasonographic examinations of the quadriceps femoris and hamstring muscle groups were performed. A follow-up ultrasound examination was performed, after an interval of 3 years, in four of these patients. Muscles were assessed subjectively as to echogenicity, determined by gray-scale assessment, and loss of normal muscle morphology. Power Doppler sonography (PDS) was used to assess vascularity. A sonographic finding of central atrophy and peripheral sparing resulting in a target-like appearance was noted in the hamstring compartment of all six patients. The quadriceps compartment also showed involvement of the rectus femoris of all patients, which, in some cases, was the only muscle involved in the quadriceps. Vascularity was markedly reduced in the affected areas, with blood flow demonstrated in the peripherally spared areas. The severity of atrophy increased with disease duration. In this case series, we describe a new sonographic finding as well as document progression of HIBM disease, which has generally been described as quadriceps sparing. The myopathic target lesion, as well as isolated rectus femoris atrophy, may provide a useful adjunct to disease diagnosis. (orig.)

  16. KOMBINASI LATIHAN EKSENTRIK M.GASTROCNEMIUS DAN LATIHAN PLYOMETRIC LEBIH BAIK DARI PADA LATIHAN EKSENTRIK M.QUADRICEPS DAN LATIHAN PLYOMETRIC TERHADAP PENINGKATAN AGILITY PADA MAHASISWA DI UNIVERSITAS ESA UNGGUL

    Directory of Open Access Journals (Sweden)

    Miranti Yolanda Anggita

    2015-08-01

    Full Text Available Increase agility for students is determined by muscular strength, speed, and flexibility. The ability of muscles to contract quickly will increase the speed of muscle in motion. Increase in speed, strength and flexibility of muscles due to stretch muscle-tendinous unit. The mechanism become the basis for moving in the shortest possible time. Agility on student issues has not received much attention, the attention of the agility found better in many athletes. This research is an experimental study to analysis at the difference between the intervention of with gastrocmineus muscle eccentric exercises and plyometric exercises with eccentric exercise quadriceps muscle and plyometric to increase agility on students at the University of Esa Unggul. A total of 40 students aged 18-21 years old who meet the criteria inclusion were randomly divided into 2 treatment groups. The old treatment group I was given quadriceps muscle eccentric and plyometric treatment group II eccentric exercise gastrocmineus muscle and plyometric exercises. Both exercise was done 3 times was given per week for 6 weeks. Agility is measured by Right-Boomerang Run Test. The results of the hypothesis testing using t-test related and different mean values obtained agility treatment group I (16,43±0.89secon and a second treatment group (16,01± 1,04seconwith p?0.05. Conclusion of the study is a combination of eccentric exercise m.gastrocnemius with plyometric exercise no better than the m.quadriceps eceentric exercises with plyometric exercises to increase agility on student at Esa Unggul University.

  17. Novel treatment of a failed quadriceps tendon repair in a diabetic patient using a patella-quadriceps tendon allograft.

    Science.gov (United States)

    Druskin, Sasha C; Rodeo, Scott A

    2013-07-01

    Recurrent quadriceps tendon rupture is a debilitating condition that may be challenging to treat, especially in the presence of systemic disease such as diabetes mellitus (Bedi et al., J Shoulder Elbow Surg 19:978-988, 2010; Chbnou and Frenette, Am J Physiol Regul Integr Comp Physiol 5:R952-R957, 2004; Chen et al., J Shoulder Elbow Surg 5:416-421, 2003). Many surgical treatment protocols have been proposed (Azar, in Canale and Beatty, eds., Campbell's Operative Orthopedics, Mosby/Elsevier, Philadelphia, PA, 2008; Ilan et al., J Am Acad Orthop Surg 3:192-200, 2003; Rodeo and Izawa, in Garrett et al., eds., Principles and Practice of Orthopedic Sports Medicine, Lippincott Williams & Wilkins, Philadelphia, PA, 2000). We report the case of a diabetic male with multiple treatment failures. He ultimately sustained a good outcome following treatment with a novel surgical technique that utilized a patella quadriceps tendon allograft. Tendon allograft-to-native bone healing had previously failed in this patient, so we used a bone-tendon construct allograft to provide an allograft bone-to-native bone healing site. Now, 13 months postoperative, the patient has increased strength, minimal pain, 20 ° of extensor lag and 130 ° of flexion.

  18. The effects of knee joint effusion on quadriceps electromyography during jogging.

    Science.gov (United States)

    Torry, Michael R; Decker, Michael J; Millett, Peter J; Steadman, J Richard; Sterett, William I

    2005-03-01

    To investigate and describe the influence of intra-articular effusion on knee joint kinematics and electromyographic (EMG) profiles during jogging. Thirteen individuals underwent a 20 cc 0.9% saline insufflation of the knee joint capsule and completed 8 jogging trials. Stance phase, sagittal plane knee joint kinematics and thigh muscular EMG profiles were compared pre- and post-insufflation utilizing a paired t-test ( = 0.05). Mild knee effusion caused a reduction in vastus medialis (p = 0.005) and lateralis (p = 0.006) EMG activity. The rectus femoris, biceps femoris and medial hamstring muscles did not exhibit changes due to this protocol. There were no changes in the sagittal plane knee joint kinematic pattern. Twenty cc effusion can cause quadriceps inhibition in the vastus medialis and the vastus lateralis in otherwise healthy individuals during jogging. This study provides baseline data for the effects of mild knee joint effusion on thigh musculature during jogging. Key Points20 cc of knee effusion can cause vastus medialis and lateralis inhibition as noted by decreases in EMG amplitude.This effusion does not appear to alter sagittal plane knee joint kinematics during jogging.This finding if different from previous work investigating knee joint kinematic changes during a less dynamic activity (gait) with 20 cc of effusion.

  19. Relationship between muscle volume and contractile properties of the human knee extensors.

    Science.gov (United States)

    Behrens, Martin; Brown, Niklas; Bollinger, Robert; Bubeck, Dieter; Mau-Moeller, Anett; Weippert, Matthias; Zschorlich, Volker; Bruhn, Sven; Alt, Wilfried

    2016-01-01

    The present study was designed to investigate the relationship between volume and electrically evoked twitch properties of the quadriceps muscle. Supramaximal single and doublet stimulation of the femoral nerve was used to assess contractile properties at 45° and 80° knee flexion. Muscle volume was measured using a 1.5-Tesla magnetic resonance imaging scanner. Quadriceps muscle volume was only significantly correlated (r = 0.629) with peak twitch torque induced by doublet stimulation at 80° but not at 45° knee flexion.

  20. Abnormalities of skeletal muscle in patients with chronic heart failure.

    Science.gov (United States)

    Lipkin, D P; Jones, D A; Round, J M; Poole-Wilson, P A

    1988-02-01

    We have examined muscle strength, mitochondrial enzyme activity, histochemistry and fibre size in the quadriceps muscle of 9 patients with severe chronic heart failure. A needle biopsy of the quadriceps muscle was taken with patients at rest. Maximum oxygen uptake was measured during treadmill exercise. Mean maximal oxygen consumption was 11.7 ml.kg-1.min-1. Isometric maximum voluntary contraction was reduced to 55% of the predicted value for weight. Eight biopsies were abnormal. Findings included increased acid phosphatase, increased interstitial cellularity, excess intracellular lipid accumulation, atrophy of both type I and II fibres and variation in size with hypertrophy and atrophy of fibers. Muscle fibre capillary density and the activity of mitochondrial enzymes were normal. Changes in skeletal muscle strength may play a role in the limitation of exercise capacity seen in patients with congestive heart failure.

  1. Ultrasound assessment of lower limb muscle mass in response to resistance training in COPD

    Directory of Open Access Journals (Sweden)

    Menon Manoj K

    2012-12-01

    Full Text Available Abstract Background Quantifying the improvements in lower limb or quadriceps muscle mass following resistance training (RT, is an important outcome measure in COPD. Ultrasound is a portable, radiation free imaging technique that can measure the size of superficial muscles belonging to the quadriceps group such as the rectus femoris, but has not been previously used in COPD patients following RT. We compared the responsiveness of ultrasound derived measures of quadriceps mass against dual energy x-ray absorptiometry (DEXA, in patients with COPD and healthy controls following a programme of high intensity knee extensor RT. Methods Portable ultrasound was used to assess the size of the dominant quadriceps in 45 COPD patients and 19 healthy controls-before, during, and after 8 weeks of bilateral high intensity isokinetic knee extensor RT. Scanning was performed at the mid-thigh region, and 2 indices of quadriceps mass were measured-rectus femoris cross-sectional area (RFcsa and quadriceps muscle thickness (Qt. Thigh lean mass (Tdexa was determined by DEXA. Results Training resulted in a significant increase in Tdexa, RFcsa and Qt in COPD patients [5.7%, 21.8%, 12.1% respectively] and healthy controls [5.4%, 19.5%, 10.9 respectively]. The effect size for the changes in RFcsa (COPD= 0.77; Healthy=0.83 and Qt (COPD=0.36; Healthy=0.78 were greater than the changes in Tdexa (COPD=0.19; Healthy=0.26 following RT. Conclusions Serial ultrasound measurements of the quadriceps can detect changes in muscle mass in response to RT in COPD. The technique has good reproducibility, and may be more sensitive to changes in muscle mass when compared to DEXA. Trial registration http://www.controlled-trials.com (Identifier: ISRCTN22764439

  2. Quadriceps exercise intolerance in patients with chronic obstructive pulmonary disease

    DEFF Research Database (Denmark)

    Gifford, Jayson R; Trinity, Joel D; Layec, Gwenael

    2015-01-01

    This study sought to determine if qualitative alterations in skeletal muscle mitochondrial respiration, associated with decreased mitochondrial efficiency, contribute to exercise intolerance in patients with chronic obstructive pulmonary disease (COPD). Using permeabilized muscle fibers from the ...

  3. Absence of muscle regeneration after implantation of a collagen matrix seeded with myoblasts

    NARCIS (Netherlands)

    van Wachem, PB; Brouwer, LA; van Luyn, MJA

    1999-01-01

    Collagens are widely used as biomaterials for e.g. soft tissue reconstruction. The present study was aimed at reconstruction of abdominal wall muscle using processed dermal sheep collagen (DSC) and myoblast seeding. Myoblasts were harvested from foetal quadriceps muscle of an inbred rat strain, cult

  4. Muscle activity during knee-extension strengthening exercise performed with elastic tubing and isotonic resistance

    DEFF Research Database (Denmark)

    Jakobsen, Markus Due; Sundstrup, Emil; Andersen, Christoffer H;

    2012-01-01

    While elastic resistance training, targeting the upper body is effective for strength training, the effect of elastic resistance training on lower body muscle activity remains questionable. The purpose of this study was to evaluate the EMG-angle relationship of the quadriceps muscle during 10-RM ...

  5. A Predictive Mathematical Model of Muscle Forces for Children with Cerebral Palsy

    Science.gov (United States)

    Lee, Samuel C. K.; Ding, Jun; Prosser, Laura A.; Wexler, Anthony S.; Binder-Macleod, Stuart A.

    2009-01-01

    Aim: The purpose of this study was to determine if our previously developed muscle model could be used to predict forces of the quadriceps femoris and triceps surae muscles of children with spastic diplegic cerebral palsy (CP). Method: Twenty-two children with CP (12 males, 10 females; mean age 10y, SD 2y, range 7-13y; Gross Motor Function…

  6. Muscle ultrasound analysis : Normal values and differentiation between myopathies and neuropathies

    NARCIS (Netherlands)

    Maurits, NM; Bollen, AE; Windhausen, A; De Jager, AEJ; Van der Hoeven, JH

    2003-01-01

    In this study, 145 healthy adults (20 to 94 years old, 69 women) were examined using ultrasound (US) imaging to obtain reference values of muscle parameters that were previously not available. We measured biceps and quadriceps sizes and subcutaneous fat thickness. To quantify muscle aspect, we defin

  7. Muscle ultrasound analysis : Normal values and differentiation between myopathies and neuropathies

    NARCIS (Netherlands)

    Maurits, NM; Bollen, AE; Windhausen, A; De Jager, AEJ; Van der Hoeven, JH

    2003-01-01

    In this study, 145 healthy adults (20 to 94 years old, 69 women) were examined using ultrasound (US) imaging to obtain reference values of muscle parameters that were previously not available. We measured biceps and quadriceps sizes and subcutaneous fat thickness. To quantify muscle aspect, we defin

  8. Influência do alongamento dos músculos isquiostibial e retofemoral no pico de torque e potência máxima do joelho Influence of stretching hamstring and quadriceps femoral muscles on knee peak torque and maximum power

    Directory of Open Access Journals (Sweden)

    Gabriel Peixoto Leão Almeida

    2009-12-01

    Full Text Available O alongamento muscular é utilizado nas práticas desportivas para aumentar a flexibilidade muscular e amplitude articular, mas estudos mostram que pode produzir efeitos deletérios na produção de força muscular. A proposta deste estudo foi verificar a influência imediata e tardia do alongamento dos músculos isquiostibiais e retofemoral, por meio da facilitação neuromuscular proprioceptiva (FNP, no pico de torque e potência máxima do joelho. Quinze jovens sedentárias foram distribuídas em três grupos: GA, submetidas a 12 sessões de alongamento durante quatro semanas; GB, a apenas uma sessão de alongamento imediatamente antes da avaliação final; e GC, à mobilização articular passiva do joelho, de forma a não alongar. Todas as participantes foram avaliadas quanto à amplitude de movimento (ADM de flexão e extensão do joelho, e à dinamometria isocinética, antes e após a intervenção, mensurando-se ADM, pico de torque (PT e potência máxima (PM do joelho. Observou-se diferença entre as médias dos três grupos na ADM após a intervenção (p0,05. Os grupos GA e GB apresentaram melhoras na ADM e apenas o grupo GC apresentou melhora significativa em todas as variáveis isocinéticas (pMuscle stretching is often used in sports practice in order to increase muscle flexibility and joint range of motion. However, many studies have shown that muscle torque production may be reduced after stretching. The purpose of this work was to assess immediate and late effects of stretching, by proprioceptive neuromuscular facilitation (PNF techniques, on knee peak torque and maximum power. Fifteen young sedentary female subjects were evenly distributed into three groups: AG, submitted to 12 PNF stretching sessions along four weeks; BG, submitted to only one stretching session just before the final evaluation; and GC, submitted to passive knee mobilization so as not to produce muscle stretching. All of them were assessed, before and after

  9. Dysfunction of endogenous pain inhibition during exercise with painful muscles in patients with shoulder myalgia and fibromyalgia.

    Science.gov (United States)

    Lannersten, Lisa; Kosek, Eva

    2010-10-01

    The aim of this study was to investigate how exercise influenced endogenous pain modulation in healthy controls, shoulder myalgia patients and fibromyalgia (FM) patients. Twenty-one healthy subjects, 20 shoulder myalgia patients and 20 FM patients, all females, participated. They performed standardized static contractions, that is, outward shoulder rotation (m. infraspinatus) and knee extension (m. quadriceps). Pressure pain thresholds (PPTs) were determined bilaterally at m. infraspinatus and m. quadriceps. During contractions PPTs were assessed at the contracting muscle, the resting homologous contralateral muscle and contralaterally at a distant site (m. infraspinatus during contraction of m. quadriceps and vice versa). Myalgia patients had lower PPTs compared to healthy controls at m. infraspinatus bilaterally (ppain regulatory mechanisms in myalgia patients during contraction of the non-afflicted m. quadriceps, but a lack of pain inhibition during contraction of the painful m. infraspinatus. FM patients failed to activate their pain inhibitory mechanisms during all contractions.

  10. Spontaneous and simultaneous bilateral rupture of the quadriceps tendon. A case report.

    Science.gov (United States)

    Alpantaki, Kaliopi; Papadokostakis, George; Katonis, Pavlos; Hadjpavlou, Alexander

    2004-02-01

    Simultaneous bilateral rupture of the quadriceps tendon has rarely been reported; it generally occurs in association with chronic metabolic disorders, such as chronic renal failure, obesity, diabetes mellitus and secondary hyperparathyroidism. The case presented here was in an 85-year-old man with no known risk factors, who sustained simultaneous and spontaneous rupture of both quadriceps tendons. The patient suffered from spinal stenosis and degenerative changes in the knee menisci. These findings suggest that instability of the knee due to meniscal damage, and quadriceps weakness as a result of spinal stenosis, may have played a significant role in the pathogenesis of this injury.

  11. Simultaneous bilateral quadriceps tendon rupture in patient with chronic renal failure.

    Science.gov (United States)

    Lee, Yunseok; Kim, Byounggook; Chung, Ju-Hwan; Dan, Jinmyoung

    2011-12-01

    Simultaneous bilateral spontaneous rupture of the quadriceps tendon is a very rare condition and only a few cases have been reported in the literature. The etiology is not clear yet. But it occurs infrequently in patients with chronic metabolic disorders. A 30-year-old female patient with simultaneous bilateral spontaneous quadriceps tendon rupture visited our hospital. She had chronic renal failure and her parathyroid hormone level was elevated due to parathyroid adenoma. We report a surgical repair of both quadriceps tendons of a patient with chronic renal failure as well as management of hyperparathyroidism.

  12. Quadriceps function following ACL reconstruction and rehabilitation : implications for optimisation of current practices

    NARCIS (Netherlands)

    Gokeler, Alli; Bisschop, Marsha; Benjaminse, Anne; Myer, Greg D.; Eppinga, Peter; Otten, Egbert

    To determine the most effective practices for quadriceps strengthening after ACL reconstruction. An electronic search has been performed for the literature appearing from January 1990 to January 2012. Inclusion criteria were articles written in English, German or Dutch with unilateral

  13. Alteration in Peripheral Muscle Strength among Overweight and Obese Individuals: A Systematic Review

    Directory of Open Access Journals (Sweden)

    Vikram Mohan

    2017-04-01

    Full Text Available Peripheral muscle dysfunction in Overweight (OW and Obesity (OB leads to fatigue and activity limitations. However, there are contradictory views regarding the exact level with regard to hand grip and quadriceps muscle strength in OW and OB. The main objective of the present systematic review was to synthesize the literature for the strength part of the hand grip and quadriceps muscle strength among OW and OB. Literature search of Scopus, EBSCO and PubMed databases from 01.01.2004 to 30.06.2016, was performed. We set our search strategy using the terms “overweight OR obesity” AND “muscle strength” AND “grip OR quadriceps”. Two reviewers administered established eligible criteria and extracted the data. Strengthening the Reporting of Observational studies in Epidemiology (STROBE was used to assess the risk of bias. Sixteen articles which were included identified Handgrip Strength (HGS, shoulder flexor, elbow flexor and knee extensor were found to be altered. There were consistent results with an increase in quadriceps muscle strength, whereas differed results were found in hand grip to increase and decrease in muscle strength in the presence of OW and OB. It is concluded that HGS appeared to be diversified with findings of increased and decrease strength, whereas regarding the quadriceps muscles, the findings were homogeneous.

  14. Surface neuromuscular electrical stimulation for quadriceps strengthening pre and post total knee replacement.

    LENUS (Irish Health Repository)

    Monaghan, Brenda

    2010-01-01

    Total knee replacement has been demonstrated to be one of the most successful procedures in the treatment of osteoarthritis. However quadriceps weakness and reductions in function are commonly reported following surgery. Recently Neuromuscular Electrical Stimulation (NMES) has been used as an adjunct to traditional strengthening programmes. This review considers the effectiveness of NMES as a means of increasing quadriceps strength in patients before and after total knee replacement.

  15. Quadriceps tendon allografts as an alternative to Achilles tendon allografts: a biomechanical comparison.

    Science.gov (United States)

    Mabe, Isaac; Hunter, Shawn

    2014-12-01

    Quadriceps tendon with a patellar bone block may be a viable alternative to Achilles tendon for anterior cruciate ligament reconstruction (ACL-R) if it is, at a minimum, a biomechanically equivalent graft. The objective of this study was to directly compare the biomechanical properties of quadriceps tendon and Achilles tendon allografts. Quadriceps and Achilles tendon pairs from nine research-consented donors were tested. All specimens were processed to reduce bioburden and terminally sterilized by gamma irradiation. Specimens were subjected to a three phase uniaxial tension test performed in a custom environmental chamber to maintain the specimens at a physiologic temperature (37 ± 2 °C) and misted with a 0.9 % NaCl solution. There were no statistical differences in seven of eight structural and mechanical between the two tendon types. Quadriceps tendons exhibited a significantly higher displacement at maximum load and significantly lower stiffness than Achilles tendons. The results of this study indicated a biomechanical equivalence of aseptically processed, terminally sterilized quadriceps tendon grafts with bone block to Achilles tendon grafts with bone block. The significantly higher displacement at maximum load, and lower stiffness observed for quadriceps tendons may be related to the failure mode. Achilles tendons had a higher bone avulsion rate than quadriceps tendons (86 % compared to 12 %, respectively). This was likely due to observed differences in bone block density between the two tendon types. This research supports the use of quadriceps tendon allografts in lieu of Achilles tendon allografts for ACL-R.

  16. [Rupture of the quadriceps tendon after lateral retinaculum release by arthroscopy].

    Science.gov (United States)

    Trobisch, P D; Baumann, M; Weise, K; Fischer, R

    2010-06-01

    Complications after arthroscopic surgery of the knee joint are infrequent. Quadriceps tendon ruptures after knee arthroscopy are rarities. Only two cases have been published in the medical literature. This article presents a case of a quadriceps tendon rupture that occurred in a 19-year-old patient 5 weeks after lateral release of the retinaculum by arthroscopy. The late occurrence differentiates this case from the other previously published cases.

  17. Surgical management of acute quadriceps tendon rupture (a case report with literature review)

    OpenAIRE

    2015-01-01

    Quadriceps tendon rupture is uncommon and often overlooked in emergency. Tearing affects weakening tendon by systemic diseases or some medications. The mechanism is generally indirect. Inability to actively extend the knee associated to a supra-patellar defect evoke easily the diagnosis without other investigations. Surgical repair is realized in emergency to completely restore the extension. We report a case of a patient who has sustained of complete quadriceps tendon tear after a long perio...

  18. Deltoid contracture: a case with multiple muscle contractures.

    Science.gov (United States)

    Chen, Hsin-Chang; Huang, Tung-Fu; Chou, Po-Hsin; Chen, Tain-Hsiung

    2008-11-01

    Deltoid contracture is relatively uncommon. The literature consists primarily of case reports and few articles on large case series. The pathogenesis has been well studied. Muscle contractures can occur in the deltoid, biceps, triceps, gluteus and quadriceps muscles; however, cases of multiple muscle contractures are rare. We reported a patient with multiple contractures of the bilateral deltoid, bilateral gluteus, and bilateral quadriceps muscles, who had received repeated intramuscular injections during childhood and adulthood. The radiographic, including magnetic resonance imaging (MRI), features of the bone and joint abnormalities are presented. Some literatures reported that damage to the structures of the body due to intramuscular injection is related to the site of injection, age of the patient, and the volume, pH, chemical composition, and diffusional capacity of the injectate. Our patient had muscular contracture induced by needle injection regardless of her age, medication and injection site.

  19. [Delayed post effort muscle soreness].

    Science.gov (United States)

    Coudreuse, J M; Dupont, P; Nicol, C

    2004-08-01

    Muscle intolerance to exercise may result from different processes. Diagnosis involves confirming first the source of pain, then potential pathological myalgia. Delayed-onset muscle soreness (DOMS), commonly referred as tiredness, occurs frequently in sport. DOMS usually develops 12-48 h after intensive and/or unusual eccentric muscle action. Symptoms usually involve the quadriceps muscle group but may also affect the hamstring and triceps surae groups. The muscles are sensitive to palpation, contraction and passive stretch. Acidosis, muscle spasm and microlesions in both connective and muscle tissues may explain the symptoms. However, inflammation appears to be the most common explanation. Interestingly, there is strong evidence that the progression of the exercise-induced muscle injury proceeds no further in the absence of inflammation. Even though unpleasant, DOMS should not be considered as an indicator of muscle damage but, rather, a sign of the regenerative process, which is well known to contribute to the increased muscle mass. DOMS can be associated with decreased proprioception and range of motion, as well as maximal force and activation. DOMS disappears 2-10 days before complete functional recovery. This painless period is ripe for additional joint injuries. Similarly, if some treatments are well known to attenuate DOMS, none has been demonstrated to accelerate either structural or functional recovery. In terms of the role of the inflammatory process, these treatments might even delay overall recovery.

  20. Bilateral simultaneous complete quadriceps rupture following chronic symptomatic tendinopathy: a case report

    Directory of Open Access Journals (Sweden)

    Arumilli Buchi

    2009-09-01

    Full Text Available Abstract Introduction Quadriceps rupture is a disabling injury mostly seen in men over 40 years of age. Bilateral quadriceps rupture is a rare injury that is often secondary to predisposing medical conditions. Ultrasound is a cheap and reliable tool for diagnosis but is operator dependent. Thus, magnetic resonance imaging is the preferred method of investigation despite its cost and availability. Prompt diagnosis and early surgical repair are needed for an optimal end result. Case presentation We report the case of a healthy 54-year-old Caucasian male farmer who presented with bilateral simultaneous complete quadriceps rupture, which was managed surgically and he was followed up for three years. He was previously under our care for enthesopathy of the quadriceps on both sides. We believe that chronic enthesopathy of the superior pole of patella made his quadriceps susceptible to complete rupture on eccentric loading. Conclusion Only a few cases of bilateral simultaneous complete quadriceps rupture in patients with symptomatic enthesopathy have been previously reported. We stress the importance of warning patients of the risk of developing complete tendon rupture when they present with an enthesopathy around the knee.

  1. [A simplified technique for repair of quadriceps tendon rupture by transpatellar PDS-cord].

    Science.gov (United States)

    Hosseini, H; Agneskirchner, J D; Lobenhoffer, P

    2005-06-01

    Quadriceps tendon ruptures are relatively unusual injuries caused by direct or more frequently indirect trauma. Since complete ruptures lead to loss of active extension of the knee joint, operative treatment is usually indicated. Several techniques are described in the literature. However, relatively little is known about the functional outcome after operative treatment of acute quadriceps tendon ruptures. We present a new operative technique using a 1.3-mm PDS cord passed through a transverse drill hole in the proximal pole of the patella. We operated ten consecutive cases of complete quadriceps tendon ruptures with the technique described between January 2000 and June 2003. Eight of ten patients were evaluated after a mean follow-up time of 38 months by physical examination, IKDC Subjective score, Lysholm and Tegner score as well as an isokinetic test of the quadriceps strength. No complications were noted in this period. The average postoperative scores were 87 (IKDC), 98 (Lysholm), and 4.5 (Tegner). Isokinetic testing showed an average of 25% quadriceps strength deficit. The operative treatment of complete quadriceps tendon ruptures using a PDS cord through a drill hole in the patella is a safe and effective technique permitting functional postoperative treatment.

  2. Efficacy of quadriceps vastus medialis dry needling in a rehabilitation protocol after surgical reconstruction of complete anterior cruciate ligament rupture

    Science.gov (United States)

    Velázquez-Saornil, Jorge; Ruíz-Ruíz, Beatriz; Rodríguez-Sanz, David; Romero-Morales, Carlos; López-López, Daniel; Calvo-Lobo, Cesar

    2017-01-01

    Abstract Background: Several new rehabilitation modalities have been proposed after anterior cruciate ligament (ACL) reconstruction. Among these, trigger point dry needling (TrP-DN) might be useful in the treatment of myofascial pain syndrome associated with ACL reconstruction to reduce pain intensity, increase knee flexion range and modify the mechanical properties of the quadriceps muscle during late-stage rehabilitation. To date, this is the first randomized clinical trial to support the use of TrP-DN in the early rehabilitation process after ACL reconstruction. The aim of this study was to determine the pain intensity, range of motion (ROM), stability, and functionality improvements by adding quadriceps vastus medialis TrP-DN to the rehabilitation protocol (Rh) provided to subacute ACL reconstructed patients. Methods: This randomized, single-blinded, clinical trial (NCT02699411) included 44 subacute patients with surgical reconstruction of complete ACL rupture. The patients were randomized into 2 intervention groups: Rh (n = 22) or Rh + TrP-DN (n = 22). Pain intensity, ROM, stability, and functionality were measured at baseline (A0) and immediately (A1), 24 hours (A2), 1 week (A3), and 5 weeks (A4) after the first treatment. Results: Comparing statistically significant differences (P ≤ .001; Eta2 = 0.198–0.360) between both groups, pain intensity (at A1), ROM (at A1, A2, and A3), and functionality (at A2, A3, and A4) were increased. Nevertheless, the rest of measurements did not show significant differences (P > .05). Conclusion: Quadriceps vastus medialis TrP-DN in conjunction with a rehabilitation protocol in subacute patients with surgical reconstruction of complete ACL rupture increases ROM (short-term) and functionality (short- to mid-term). Although there was an increase in pain intensity with the addition of TrP-DN, this was not detected beyond immediately after the first treatment. Furthermore, stability does not seem to be

  3. Acute fatigue impairs neuromuscular activity of anterior cruciate ligament-agonist muscles in female team handball players

    DEFF Research Database (Denmark)

    Zebis, M K; Bencke, J; Andersen, L L

    2011-01-01

    In sports, like team handball, fatigue has been associated with an increased risk of anterior cruciate ligament (ACL) injury. While effects of fatigue on muscle function are commonly assessed during maximal isometric voluntary contraction (MVC), such measurements may not relate to the muscle...... for neuromuscular activity [electromyography (EMG)] during a sidecutting maneuver on a force plate, pre and post a simulated handball match. MVC was obtained during maximal isometric quadriceps and hamstring contraction. The simulated handball match consisted of exercises mimicking handball match activity. Whereas...... the simulated handball match induced a decrease in MVC strength for both the quadriceps and hamstring muscles (P

  4. Muscle co-contraction during gait in individuals with articular cartilage defects in the knee.

    Science.gov (United States)

    Thoma, Louise M; McNally, Michael P; Chaudhari, Ajit M; Flanigan, David C; Best, Thomas M; Siston, Robert A; Schmitt, Laura C

    2016-07-01

    Increased muscle co-contraction during gait is common in individuals with knee pathology, and worrisome as it is known to amplify tibiofemoral compressive forces. While knees with articular cartilage defects (ACD) are more vulnerable to compressive forces, muscle co-contraction has never been reported in this population. The purpose of this study was to evaluate the extent to which individuals with ACDs in the knee demonstrate elevated quadriceps to hamstrings muscle co-contraction on the involved limb during gait compared to the uninvolved limb and to healthy controls. We also explored the impact of participant characteristics and knee impairments on co-contraction. Twenty-nine individuals with full-thickness knee ACDs (ACD group) and 19 healthy adults (control group) participated in this study. Participants performed five gait trials at self-selected speed, during which activity of the quadriceps and hamstrings muscles were collected with surface electromyography. Three-dimensional motion capture was used to define phases of gait. Quadriceps strength and self-reported outcomes were also assessed in the same session. There were no differences in quadriceps: hamstrings co-contraction between the ACD and control groups, or between the involved and uninvolved limb for the ACD group. For both ACD and control groups, co-contraction was highest in early stance and lowest in late stance. Quadriceps strength was consistently the strongest predictor of muscle co-contraction in both the ACD and the control groups, with individuals with lower strength demonstrating greater co-contraction. Further study is needed to understand the effect of increased muscle co-contraction on joint compressive forces in the presence of varied quadriceps strength.

  5. Patellar tendon straps decrease pre-landing quadriceps activation in males with patellar tendinopathy.

    Science.gov (United States)

    Rosen, Adam B; Ko, Jupil; Simpson, Kathy J; Brown, Cathleen N

    2017-03-01

    To determine if patellar tendon straps altered quadriceps' muscle activity during a drop-jump landing in males with and without patellar tendinopathy. Case-control. Biomechanics Research Laboratory. Twenty recreationally-active males participated: ten (age = 21.3 ± 2.4 years, height = 182.8 ± 5.3 cm, mass = 81.7 ± 8.6 kg) with patellar tendinopathy; ten (age = 22.0 ± 1.6 years, height = 185.7 ± 4.5 cm, mass = 82.2 ± 9.8 kg) were healthy with no history of tendinopathy. Electromyography (EMG) data for the vastus medialis (VM), rectus femoris (RF), and vastus lateralis (VL) muscles were collected. Five 2-legged 40 cm drop-jumps were performed wearing a patellar tendon strap and 5 with no-strap in a counterbalanced order. Root-mean square EMG (REMG) values of the VM, RF, and VL were averaged for a pre-landing and post-landing interval. Multiple mixed-model two-way ANOVAs were performed to determine the effect of tendinopathy and strapping condition on REMG values for each muscle. For the pre-landing interval, all participants displayed lesser VL EMG activation (0.44 ± 0.19%, 0.53 ± 0.27%, respectively; p = 0.007, d = 0.39) in the no-strap compared with the strap condition. When wearing a strap, all participants demonstrated lower VL activation prior to landing which may be helpful in reducing tensile stress at the tendon. These effects may be clinically important in modulating pain in those with patellar tendinopathy. Copyright © 2016 Elsevier Ltd. All rights reserved.

  6. Muscle force estimation with surface EMG during dynamic muscle contractions: a wavelet and ANN based approach.

    Science.gov (United States)

    Bai, Fengjun; Chew, Chee-Meng

    2013-01-01

    Human muscle force estimation is important in biomechanics studies, sports and assistive devices fields. Therefore, it is essential to develop an efficient algorithm to estimate force exerted by muscles. The purpose of this study is to predict force/torque exerted by muscles under dynamic muscle contractions based on continuous wavelet transform (CWT) and artificial neural networks (ANN) approaches. Mean frequency (MF) of the surface electromyography (EMG) signals power spectrum was calculated from CWT. ANN models were trained to derive the MF-force relationships from the subset of EMG signals and the measured forces. Then we use the networks to predict the individual muscle forces for different muscle groups. Fourteen healthy subjects (10 males and 4 females) were voluntarily recruited in this study. EMG signals were collected from the biceps brachii, triceps, hamstring and quadriceps femoris muscles to evaluate the proposed method. Root mean square errors (RMSE) and correlation coefficients between the predicted forces and measured actual forces were calculated.

  7. Differential Muscle Involvement in Mice and Humans Affected by McArdle Disease

    DEFF Research Database (Denmark)

    Krag, Thomas O; Pinós, Tomàs; Nielsen, Tue L;

    2016-01-01

    , variations in fiber size, vacuoles, and some internal nuclei associated with cytosolic glycogen accumulation and ongoing regeneration; structural damage was seen only in a minority of human patients. Neither liver nor brain isoforms of glycogen phosphorylase were upregulated in muscles, thus providing...... no substitution for the missing muscle isoform. In the mice, the tibialis anterior (TA) muscles were invariably more damaged than the quadriceps muscles. This may relate to a 7-fold higher level of myophosphorylase in TA compared to quadriceps in wild-type mice and suggests higher glucose turnover in the TA. Thus......McArdle disease (muscle glycogenosis type V) is caused by myophosphorylase deficiency, which leads to impaired glycogen breakdown. We investigated how myophosphorylase deficiency affects muscle physiology, morphology, and glucose metabolism in 20-week-old McArdle mice and compared the findings...

  8. Rules of tissue packing involving different cell types: human muscle organization.

    Science.gov (United States)

    Sánchez-Gutiérrez, Daniel; Sáez, Aurora; Gómez-Gálvez, Pedro; Paradas, Carmen; Escudero, Luis M

    2017-01-10

    Natural packed tissues are assembled as tessellations of polygonal cells. These include skeletal muscles and epithelial sheets. Skeletal muscles appear as a mosaic composed of two different types of cells: the "slow" and "fast" fibres. Their relative distribution is important for the muscle function but little is known about how the fibre arrangement is established and maintained. In this work we capture the organizational pattern in two different healthy muscles: biceps brachii and quadriceps. Here we show that the biceps brachii muscle presents a particular arrangement, based on the different sizes of slow and fast fibres. By contrast, in the quadriceps muscle an unbiased distribution exists. Our results indicate that the relative size of each cellular type imposes an intrinsic organization into natural tessellations. These findings establish a new framework for the analysis of any packed tissue where two or more cell types exist.

  9. Quantitative muscle ultrasound measures rapid declines over time in children with SMA type 1.

    Science.gov (United States)

    Ng, Kay W; Connolly, Anne M; Zaidman, Craig M

    2015-11-15

    Muscles are small in spinal muscular atrophy (SMA). It is not known if muscle size changes over time in SMA type 1. We quantified changes over time in muscle size and echointensity during two repeated ultrasound examinations of unilateral proximal (biceps brachii/brachialis and quadriceps) and distal (anterior forearm flexors and tibialis anterior) muscles in three children with SMA type 1. We compared muscle thickness (MT) to body weight-dependent normal reference values. Children were 1, 6, and 11months old at baseline and had 2, 2 and 4 months between ultrasound examinations, respectively. At baseline, MT was normal for weight in all muscles except an atrophic quadriceps in the oldest child. MT decreased and echointensity increased (worsened) over time. At follow up, MT was below normal for weight in the quadriceps in all three children, in the biceps/brachioradialis in two, and in the anterior forearm in one. Tibialis anterior MT remained normal for weight in all three children. Muscle echointensity increased over time in all muscles and, on average, more than doubled in two children. In children with SMA type 1, muscle atrophies and becomes hyperechoic over time. Quantitative muscle ultrasound measures disease progression in SMA type 1 that warrants additional study in more children. Copyright © 2015. Published by Elsevier B.V.

  10. Bilateral quadriceps tendon ruptures in a healthy, active duty soldier: case report and review of the literature.

    Science.gov (United States)

    Johnson, Anthony E; Rose, Stephen D

    2006-12-01

    Unilateral quadriceps tendon ruptures are not uncommon. These injuries have been reported to occur spontaneously and after seemingly trivial trauma in elderly individuals, patients undergoing renal dialysis, and patients with metabolic derangements such as hyperparathyroidism. In young patients, unilateral quadriceps tendon ruptures have been reported as complications of burns, anabolic steroid abuse, and elective orthopedic surgery. Bilateral quadriceps tendon ruptures in young healthy patients are rare injuries. We present the case of a young, healthy, active duty soldier who sustained bilateral quadriceps tendon ruptures after a relatively minor trauma.

  11. Fibrosis and inflammation are greater in muscles of beta-sarcoglycan-null mouse than mdx mouse.

    Science.gov (United States)

    Gibertini, Sara; Zanotti, Simona; Savadori, Paolo; Curcio, Maurizio; Saredi, Simona; Salerno, Franco; Andreetta, Francesca; Bernasconi, Pia; Mantegazza, Renato; Mora, Marina

    2014-05-01

    The Sgcb-null mouse, with knocked-down β-sarcoglycan, develops severe muscular dystrophy as in type 2E human limb girdle muscular dystrophy. The mdx mouse, lacking dystrophin, is the most used model for Duchenne muscular dystrophy (DMD). Unlike DMD, the mdx mouse has mild clinical features and shows little fibrosis in limb muscles. To characterize ECM protein deposition and the progression of muscle fibrosis, we evaluated protein and transcript levels of collagens I, III and VI, decorin, and TGF-β1, in quadriceps and diaphragm, at 2, 4, 8, 12, 26, and 52 weeks in Sgcb-null mice, and protein levels at 12, 26, and 52 weeks in mdx mice. In Sgcb-null mice, severe morphological disruption was present from 4 weeks in both quadriceps and diaphragm, and included conspicuous deposition of extracellular matrix components. Histopathological features of Sgcb-null mouse muscles were similar to those of age-matched mdx muscles at all ages examined, but, in the Sgcb-null mouse, the extent of connective tissue deposition was generally greater than mdx. Furthermore, in the Sgcb-null mouse, the amount of all three collagen isoforms increased steadily, while, in the mdx, they remained stable. We also found that, at 12 weeks, macrophages were significantly more numerous in mildly inflamed areas of Sgcb-null quadriceps compared to mdx quadriceps (but not in highly inflamed regions), while, in the diaphragm, macrophages did not differ significantly between the two models, in either region. Osteopontin mRNA was also significantly greater at 12 weeks in laser-dissected highly inflamed areas of the Sgcb-null quadriceps compared to the mdx quadriceps. TGF-β1 was present in areas of degeneration-regeneration, but levels were highly variable and in general did not differ significantly between the two models and controls. The roles of the various subtypes of macrophages in muscle repair and fibrosis in the two models require further study. The Sgcb-null mouse, which develops early fibrosis

  12. [Paragliding-associated bilateral partial rupture of the rectus femoris muscle].

    Science.gov (United States)

    Schulze Bertelsbeck, D; Veelken, D

    2004-12-01

    Pain in the thigh or groin due to a rupture of the rectus femoris muscle is rather uncommon. We report on a patient with a bilateral rupture of the rectus femoris muscle that occurred due to a landing maneuver while para-gliding. The diagnosis was confirmed by ultrasound and MRI. Additionally, an old unilateral anterior cruciate ligament rupture was present. As a functional deficit of the quadriceps muscle could not be observed, a primarily conservative treatment seems to be appropriate.

  13. GH administration changes myosin heavy chain isoforms in skeletal muscle but does not augment muscle strength or hypertrophy, either alone or combined with resistance exercise training in healthy elderly men

    DEFF Research Database (Denmark)

    Lange, Kai Henrik Wiborg; Andersen, Jesper Løvind; Beyer, Nina

    2002-01-01

    ) quadriceps muscle power; 3) quadriceps muscle fiber type, size, and myosin heavy chain (MHC) composition; 4) quadriceps cross-sectional area (CSA) [nuclear magnetic resonance imaging (NMRI)]; 5) body composition (dual-energy x-ray absorptiometry scanning); and 6) GH-related serum markers were performed......GH administration, either alone or combined with resistance exercise training (RT), has attracted interest as a means of increasing muscle mass and strength in the elderly. In the present study, 31 healthy, elderly men [age, 74 +/- 1 yr (mean +/- SEM)] were assigned to either RT [3 sessions/wk, 3...... by additional GH administration. In the RT + GH group, there was a significant decrease in MHC 1 and 2X isoforms, whereas MHC 2A increased. RT, therefore, seems to overrule the changes in MHC composition induced by GH administration alone. Changes in body composition confirmed previous reports of decreased fat...

  14. Chondropathia patellae and knee muscle control. An electromyographic study.

    Science.gov (United States)

    Hess, T; Gleitz, M; Egert, S; Hopf, T

    1996-01-01

    The activity of knee-related muscles was registered via exercising on a bicycle ergometer by 17 patients with clinically diagnosed chondropathia patellae. M. quadriceps activity was shorter and the hamstring activity longer in the chondropathy group compared with a matched healthy control group. The changes in m. quadriceps occurred to an almost equal extent in lateral and medial sections. In five patients with unilateral complaints, the electromyographic changes were nevertheless noted on both sides. The study shows that chondropathia patellae involves a change in muscle control affecting not only the knee extensors but also the hamstrings. Through the changed innervation pattern the coactivation phase, i.e. the phase of simultaneous activation of knee flexors and extensors at the end of the extension phase, takes place at a higher angle of flexion. Physiotherapy should involve all knee-related muscles and should include not only isometric but also dynamic exercises.

  15. Expression of interleukin-15 in human skeletal muscle effect of exercise and muscle fibre type composition

    DEFF Research Database (Denmark)

    Nielsen, Anders Rinnov; Mounier, Remi; Plomgaard, Peter

    2007-01-01

    of recovery without any changes in muscle IL-15 protein content or plasma IL-15 at any of the investigated time points. In conclusion, IL-15 mRNA level is enhanced in skeletal muscles dominated by type 2 fibres and resistance exercise induces increased muscular IL-15 mRNA levels. IL-15 mRNA levels in skeletal......The cytokine interleukin-15 (IL-15) has been demonstrated to have anabolic effects in cell culture systems. We tested the hypothesis that IL-15 is predominantly expressed by type 2 skeletal muscle fibres, and that resistance exercise regulates IL-15 expression in muscle. Triceps brachii, vastus...... lateralis quadriceps and soleus muscle biopsies were obtained from normally physically active, healthy, young male volunteers (n = 14), because these muscles are characterized by having different fibre-type compositions. In addition, healthy, normally physically active male subjects (n = 8) not involved...

  16. Traumatic quadriceps rupture in a patient with patellectomy: a case report

    Directory of Open Access Journals (Sweden)

    Shanmugam Chezhiyan

    2007-11-01

    Full Text Available Abstract Introduction Acute traumatic, unilateral, quadriceps rupture after patellectomy is rare. Case presentation We present a 42-year old male who experienced a unilateral left quadriceps tendon rupture following assault by four people. Twenty-seven years before this injury, the patient had suffered ipsilateral femur and comminuted patellar fractures, which were managed by intramedullary nailing and patellectomy respectively. We performed primary end to end repair of the torn tendon. Postoperatively, histology revealed findings consistent with pre-existent degenerative changes. The patient made good recovery, and returned to his former occupation which was reliant on his ability to drive. Conclusion Degenerative changes of the tendon of the extensor mechanism of knee following patellectomy may predispose the quadriceps tendon to traumatic rupture. Early operative intervention and protracted rehabilitation are required to obtain the best functional results.

  17. Surgical Treatment of Neglected Traumatic Quadriceps Tendon Rupture with Knee Ankylosis.

    Science.gov (United States)

    Lee, Seung-Hun; Song, Eun-Kyoo; Seon, Jong-Keun; Woo, Seong-Hwan

    2016-06-01

    Quadriceps tendon rupture is an uncommon injury. This disabling condition is the result of direct or indirect trauma. It requires surgical repair to avoid poor outcomes in cases of neglected or chronic rupture. In most acute cases, simple tendon suture or reinsertion is suitable for an extensor mechanism reconstruction of the knee joint. However, chronic lesions often require a tendon graft or flap reconstruction. We report a case of a 15-year-old male who was diagnosed with a chronic quadriceps rupture with a patellar superior pole fracture. We performed quadriceps reconstruction using tibialis anterior allograft tendon and additional screw fixation to reconstruct the extensor mechanism and recover knee joint range of motion to prevent a high-level functional restriction. The treatment was difficult and limited due to neglect for 9-months that led to ankylosis accompanied with nonunion of tibial fracture. Our surgical treatment using allograft tendon resulted in a very good outcome after 30 months of follow-up.

  18. Synchronous quadriceps tendon rupture and unilateral ACL tear in a weightlifter, associated with anabolic steroid use.

    Science.gov (United States)

    Fenelon, Christopher; Dalton, David M; Galbraith, John G; Masterson, Eric L

    2016-05-06

    Synchronous quadriceps tendon rupture is rare. A 29-year-old man, an amateur weight lifter, taking androgenic-anabolic steroids (AAS), developed sudden onset bilateral pain and swelling of his anterior thighs when attempting to squat 280 kg (620 lb). Examination revealed gross swelling superior to the patella and palpable gaps in both quadriceps tendons. He underwent successful operative repair. MRI revealed a partial tear of the anterior cruciate ligament (ACL) of the right knee. This was not reconstructed. Only a few case reports of the association between AAS and quadriceps rupture exist in the literature, with none to the best of our knowledge in the past 10 years. ACL rupture coexisting is very rare, with only two reported cases.

  19. Adductor Canal Block With 10 mL Versus 30 mL Local Anesthetics and Quadriceps Strength

    DEFF Research Database (Denmark)

    Jæger, Pia; Koscielniak-Nielsen, Zbigniew J; Hilsted, Karen Lisa;

    2015-01-01

    BACKGROUND AND OBJECTIVES: Adductor canal block (ACB) is predominantly a sensory nerve block, but excess volume may spread to the femoral triangle and reduce quadriceps strength. We hypothesized that reducing the local anesthetic volume from 30 to 10 mL may lead to fewer subjects with quadriceps...

  20. Osteotendinous repair of bilateral spontaneous quadriceps tendon ruptures with the Krackow technique in two patients with chronic renal failure.

    Science.gov (United States)

    Kara, Adnan; Sari, Seçkin; Şeker, Ali; Öztürk, Irfan

    2013-01-01

    Although unilateral traumatic quadriceps tendon rupture is a relatively frequent pathology, bilateral non-traumatic spontaneous ruptures are uncommon and are usually associated with chronic renal failure, hyperparathyroidism, gout, and systemic lupus erythematosus. This paper aimed to discuss two patients with chronic renal failure treated with the Krackow suture technique for spontaneous bilateral quadriceps tendon rupture.

  1. Spontaneous and simultaneous bilateral rupture of the quadriceps tendon in a patient with osteogenesis imperfecta: a case report.

    Science.gov (United States)

    Figueroa, David; Calvo, Rafael; Vaisman, Alex

    2006-03-01

    Bilateral rupture of the quadriceps tendon is an uncommon and serious injury that usually occurs in middle aged to elderly patients. It is frequently associated with chronic metabolic disorders like diabetes, hyperparathyroidism, gout, chronic renal failure or the chronic use of steroids. We report a case of spontaneous bilateral rupture of the quadriceps tendon in a patient with osteogenesis imperfecta.

  2. Chronic quadriceps rupture: treatment with lengthening and early mobilization without cerclage augmentation and a report of three cases.

    Science.gov (United States)

    Rizio, Louis; Jarmon, Nicholas

    2008-01-01

    In this study, 3 patients with chronic quadriceps tears and gaps tendon, repair of the tendon through drill holes in the patella without cerclage augmentation, and early mobilization. The gap was quadriceps tendon. Results of this technique are presented with a minimum of 1-year follow-up.

  3. [Variation of muscle mass and weight in critical patient].

    Science.gov (United States)

    Valls-Matarín, J; del Cotillo-Fuente, M; Grané-Mascarell, N; Quintana, S

    2015-01-01

    Quantify the muscle mass and body weight variation in critically ill patients and to identify associated factors. A descriptive follow-up study. Data for demographic variables, body weight, fluid balance, daily kilocalories, the amount of sedation and muscle relaxants received and motor physiotherapy applied were collected. Three consecutive measurements were performed in the brachial biceps and quadriceps rectus by using ultrasound, upon admission and every 5 days until discharge. 68 patients were included. Average age was of 73.5 [57-78,5] years. The median length of stay was 9.5 [5.5 -15] days. The median 16 (SD=5.7) daily kilocalories per kg/weight, 91.2% received sedation, 44.1% received muscle relaxants and 20% received physiotherapy. The patients presented a muscle wasting of 4.9 (SD=3.9)mm, p <.001 in the brachial biceps and 5.6 (SD=4.8)mm, p <.001 in the quadriceps rectus. Regression analysis selected the length of stay and the muscle relaxants are the most influential variables in the brachial biceps muscle wasting (R2=0.4), and length of stay as the most influential in the quadriceps rectus muscle wasting (R2=0.3). Patient's mean body weight on admission was of 81.1 (SD=15)kg and 81.2 (SD=14.2)kg on discharge, p=.95. The critically ill patient presents a significant muscle waste related with the length of stay and the treatment received with muscle relaxants. Patients are being discharged with a similar body weight to which they were admitted but with a significant reduction of muscle mass. Copyright © 2014 Elsevier España, S.L.U. y SEEIUC. All rights reserved.

  4. [Bilateral quadriceps rupture in a patient with osteogenesis imperfecta. A case report].

    Science.gov (United States)

    Salcedo-Dueñas, Jesús Alejandro; Torres Castro, Carlos; Estrada Gómez, José Andrés; Algarín Reyes, José Antonio; Bello González, Alejandro

    2009-01-01

    We present the case of a 24-year-old patient with bilateral quadriceps rupture and history of type I congenital osteogenesis imperfecta diagnosed clinically and with ultrasound. Bilateral quadriceps tenoplasty was performed with an anterior approach and without any complications. The patient was discharged with bilateral neoprene knee-guards. The sutures were removed at the 21-day follow-up visit, rehabilitation was started at six weeks and the patient was doing well at the 2- and 3-month follow-up visits. Timely management and early rehabilitation contribute to decrease the risk of sequelae despite the poor functional prognosis.

  5. Simultaneous Bilateral Quadriceps Tendon Rupture following Long-Term Low-Dose Nasal Corticosteroid Application

    Directory of Open Access Journals (Sweden)

    Mohamed Omar

    2013-01-01

    Full Text Available Simultaneous bilateral quadriceps tendon rupture is a very rare injury, which was previously only described in slightly more than 100 cases in the English literature. Occurrence after minor trauma is predominantly associated with certain medical conditions including chronic diseases and long-term use of certain drugs. We report the case of a 61-year-old healthy patient who sustained a simultaneous bilateral quadriceps tendon rupture following minor trauma. Medical history was completely clear except of a long-term nasal corticosteroid medication due to allergic rhinitis.

  6. Suture anchor versus suture through tunnel fixation for quadriceps tendon rupture: a biomechanical study.

    Science.gov (United States)

    Lighthart, William A; Cohen, David A; Levine, Richard G; Parks, Brent G; Boucher, Henry R

    2008-05-01

    This biomechanical study compared suture anchors versus transosseous sutures for repair of quadriceps tendon ruptures using a force of 150 N at a frequency of 0.5 Hz. No significant difference in displacement was found between the 2 techniques with initial loading or with load or no load after 1000 cycles. Displacement after 1000 cycles for suture anchors and bone tunnels was 4.65 and 4.50 mm, respectively. These findings suggest a possible role for suture anchors in repairing quadriceps tendon ruptures. Suture anchors are relatively expensive but require less dissection over the patella and do not involve suture placement about the patella tendon.

  7. Impact of quadriceps strengthening on response to fatiguing exercise following ACL reconstruction.

    Science.gov (United States)

    Kuenze, Christopher; Eltoukhy, Moataz; Kelly, Adam; Kim, Chang-Young

    2017-01-01

    Patients commonly experience altered response to fatiguing exercise after ACL reconstruction (ACLR). The objective of this study was to assess the impact of quadriceps strengthening on response to exercise after ACLR. Clinical trial. Ten participants with a history of primary, unilateral ACLR (sex=9F/1M, age=21.0±2.8 years, BMI=23.7±2.7kg/m(2)) and 10 healthy participants (sex=9F/1M, age=22.2±3.2 years, BMI=23.8±3.9kg/m(2)) participated. ACLR participants completed a 2-week quadriceps strengthening intervention including 14 progressive strengthening exercise sessions. Normalized knee extension maximum voluntary isometric contraction (MVIC) torque (Nm/kg) and quadriceps central activation ratio (%, CAR) were measured before and after a 30-minute fatiguing exercise protocol. ACLR participants completed testing before and after the 2-week intervention while control participants completed a single testing session. The intervention significantly improved normalized knee extension MVIC torque (pre-intervention=1.85±0.67Nm/kg, post-intervention=2.09±0.81Nm/kg, p=0.04) and quadriceps CAR in the ACLR involved limb (pre-intervention=86.51±5.03%, post-intervention=92.94±5.99%, p=0.02). Quadriceps CAR (pre-intervention=1.13±9.04%, post-intervention=-3.97±4.59%, p=0.16) and normalized knee extension MVIC torque (pre-intervention=0.26±20.90%, post-intervention=-8.02±12.82%, p=0.30) response to exercise did not significantly change from pre-intervention to post-intervention conditions. Two weeks of quadriceps strengthening reduced this between group difference in the involved limb which may indicate restoration of more optimal quadriceps neuromuscular function and increased demand on the quadriceps during physical activity. Copyright © 2016 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

  8. A novel noninvasive method for measuring fatigability of the quadriceps muscle in noncooperating healthy subjects

    DEFF Research Database (Denmark)

    Poulsen, Jesper Brøndum; Rose, Martin Høyer; Møller, Kirsten

    2015-01-01

    of peak torque values were primary outcome measures. For twitch contractions, maximum peak torque and rise time were calculated. Relative (intraclass correlation, ICC3.1) and absolute (standard error of measurement, SEM) reliability were assessed and minimum detectable change was calculated using a 95......% confidence interval (MDC95%). Results. The Fatigue Index (ICC3.1, 0.84; MDC95%, 0.12) and the slope of the regression line (ICC3.1, 0.99; MDC95%, 0.03) showed substantial relative and absolute reliability during the first 15 and 30 contractions, respectively. Conclusion. This method for assessing...

  9. The twitch interpolation technique for study of fatigue of human quadriceps muscle

    DEFF Research Database (Denmark)

    Bülow, P M; Nørregaard, J; Mehlsen, J;

    1995-01-01

    technique. Then an endurance test was performed in which the subjects made repeated isometric contractions at 50% of the 'true' maximum torque for 4 s, separated by 6 s rest periods. During the test, the force response to single electrical stimulation (twitch amplitude) was measured at 50% and 25......% of the estimated maximum torque. In 10 subjects, the test was repeated 2-4 weeks later. Twitch amplitudes at 50% of maximum torque declined exponentially with time in 20 of 21 subjects. The distribution of the exponential rate constant was skewed with a mean of 4.6 h-1 and range of 0.3-21.5 h-1. After...... logarithmical transformation, the distribution of the exponential rate constant fitted closely to a normal distribution, and the inter-individual variation was SD = 1.15 compared to an intra-individual variation of 0.29. The coefficient of correlation for repeated determination was 0.91 (P

  10. The effect of increase in baggage weight on elderly women's lower extremity muscle activation during gait.

    Science.gov (United States)

    Kim, Seong-Gil; Nam, Chan-Woo; Yong, Min-Sik

    2014-01-01

    The aim of the present study was to examine the effect of increased baggage weight on the muscle activation of elderly women's lower extremities during gait. A total of 24 elderly women who were residing in communities in Daegu, South Korea aged 79.6±6.2, 149.7±7.0cm in height, and 53.5±7.2kg in weight participated in this study. The muscle activation of each muscle was measured three times at 2kg, 3kg, and 4kg of baggage weight while the subjects were conducting treadmill walking wearing backpacks. Electrodes were placed on four muscles: the quadriceps muscle (rectus femoris), the hamstring muscle (semitendinosus), the tibialis anterior muscle, and the soleus muscle. The results show that the rates of increase in muscle activation in the tibialis anterior and soleus muscles according to baggage weight increase were higher than those in the quadriceps and hamstring muscles (<0.05). These results indicate that the heavier weight loads increase the activation of muscles that control the ankle joints causing muscle fatigue. Moreover, a decrease in balance ability through muscle fatigue can be a risk factor for falls. Thus, elderly people should be instructed not to carry heavy objects.

  11. Co-activation of sprinter and distance runner muscles in isokinetic exercise.

    Science.gov (United States)

    Osternig, L R; Hamill, J; Lander, J E; Robertson, R

    1986-08-01

    The purpose of this study was to investigate the extent of co-activation of quadriceps and hamstring musculature in sprinters and distance runners. Nine female intercollegiate track athletes performed maximal knee extensions and flexions on a modified orthotron isokinetic dynamometer at two speeds (100 degrees and 400 degrees X s-1). Simultaneous recordings of torque, joint position, and agonist/antagonist electromyographic activity from the quadriceps and hamstrings were computer-processed. The results revealed the hamstrings to be considerably more active during knee extension than the quadriceps during flexion. The integrated electromyographic activity of co-contracting hamstrings and quadriceps, throughout the joint range, averaged 33 and 6%, respectively, of the same muscle group during its agonist phase. Hamstring co-activation increased sharply during the last 25% of knee extension, generating 58% of the integrated electromyographic agonist activity. Co-activation of the sprinters' hamstrings was four times that of distance runners (57/14%), however, the faster speed of movement (400 degrees X s-1) increased hamstring coactivation of distance runners more acutely than sprinters in the final phase of extension. The data suggest that the hamstrings are used to a much greater extent than quadriceps for limb deceleration and that the distraction of antagonist muscle tension should be considered when analyzing agonist isokinetic torques. Furthermore, the relatively high co-activation of the hamstrings, particularly during the last 25% of extension, may induce hamstring soreness or strain in vulnerable subjects.

  12. Muscle activity during knee-extension strengthening exercise performed with elastic tubing and isotonic resistance

    DEFF Research Database (Denmark)

    Jakobsen, Markus Due; Sundstrup, Emil; Andersen, Christoffer H;

    2012-01-01

    BACKGROUND/PURPOSE: While elastic resistance training, targeting the upper body is effective for strength training, the effect of elastic resistance training on lower body muscle activity remains questionable. The purpose of this study was to evaluate the EMG-angle relationship of the quadriceps ...

  13. Combined inhibition of nitric oxide and prostaglandins reduces human skeletal muscle blood flow during exercise

    DEFF Research Database (Denmark)

    Boushel, Robert Christopher; Langberg, Henning; Gemmer, Carsten;

    2002-01-01

    The vascular endothelium is an important mediator of tissue vasodilatation, yet the role of the specific substances, nitric oxide (NO) and prostaglandins (PG), in mediating the large increases in muscle perfusion during exercise in humans is unclear. Quadriceps microvascular blood flow was quanti...

  14. Muscle strength and knee range of motion after femoral lengthening

    Science.gov (United States)

    Bhave, Anil; Shabtai, Lior; Woelber, Erik; Apelyan, Arman; Paley, Dror; Herzenberg, John E

    2017-01-01

    Background and purpose Femoral lengthening may result in decrease in knee range of motion (ROM) and quadriceps and hamstring muscle weakness. We evaluated preoperative and postoperative knee ROM, hamstring muscle strength, and quadriceps muscle strength in a diverse group of patients undergoing femoral lengthening. We hypothesized that lengthening would not result in a significant change in knee ROM or muscle strength. Patients and methods This prospective study of 48 patients (mean age 27 (9–60) years) compared ROM and muscle strength before and after femoral lengthening. Patient age, amount of lengthening, percent lengthening, level of osteotomy, fixation time, and method of lengthening were also evaluated regarding knee ROM and strength. The average length of follow-up was 2.9 (2.0–4.7) years. Results Mean amount of lengthening was 5.2 (2.4–11.0) cm. The difference between preoperative and final knee flexion ROM was 2° for the overall group. Congenital shortening cases lost an average of 5% or 6° of terminal knee flexion, developmental cases lost an average of 3% or 4°, and posttraumatic cases regained all motion. The difference in quadriceps strength at 45° preoperatively and after lengthening was not statistically or clinically significant (2.7 Nm; p = 0.06). Age, amount of lengthening, percent lengthening, osteotomy level, fixation time, and lengthening method had no statistically significant influence on knee ROM or quadriceps strength at final follow-up. Interpretation Most variables had no effect on ROM or strength, and higher age did not appear to be a limiting factor for femoral lengthening. Patients with congenital causes were most affected in terms of knee flexion. PMID:27892743

  15. Acute effects of static and dynamic stretching on hamstring eccentric isokinetic strength and unilateral hamstring to quadriceps strength ratios.

    Science.gov (United States)

    Ayala, Francisco; De Ste Croix, Mark; Sainz De Baranda, Pilar; Santonja, Fernando

    2013-01-01

    The main purposes of this study were to investigate the acute effects of static and dynamic lower limb stretching routines: (a) on peak torque, total external work and joint angle at peak torque of the hamstrings during maximal eccentric isokinetic leg flexion; (b) on unilateral hamstring to quadriceps (H/Q) strength ratios; as well as (c) to determine whether static and dynamic routines elicit similar responses. A total of 49 active adults completed the following intervention protocols in a randomised order on separate days: (a) non-stretching (control condition), (b) static stretching, and (c) dynamic stretching. After the stretching or control intervention, eccentric isokinetic peak torque, the angle of peak torque and total external work were assessed with participants prone at 1.04 and 3.14 rad · s(-1). Unilateral strength ratios of the knee were also recorded. Measures were compared via a fully-within-groups factorial analysis of variance (ANOVA). There were no main effects for eccentric isokinetic peak torque, angle of peak torque, total external work and unilateral H/Q strength ratios. The results suggest that dynamic and static stretching has no influence on eccentric strength profile and unilateral H/Q strength ratios and hence both forms of stretching do not reduce these two primary risk factors for muscle injury.

  16. Evaluation of central and peripheral fatigue in the quadriceps using fractal dimension and conduction velocity in young females.

    Directory of Open Access Journals (Sweden)

    Matteo Beretta-Piccoli

    Full Text Available Over the past decade, linear and non-linear surface electromyography descriptors for central and peripheral components of fatigue have been developed. In the current study, we tested fractal dimension (FD and conduction velocity (CV as myoelectric descriptors of central and peripheral fatigue, respectively. To this aim, we analyzed FD and CV slopes during sustained fatiguing contractions of the quadriceps femoris in healthy humans.A total of 29 recreationally active women (mean age±standard deviation: 24±4 years and two female elite athletes (one power athlete, age 24 and one endurance athlete, age 30 years performed two knee extensions: (1 at 20% maximal voluntary contraction (MVC for 30 s, and (2 at 60% MVC held until exhaustion. Surface EMG signals were detected from the vastus lateralis and vastus medialis using bidimensional arrays.Central and peripheral fatigue were described as decreases in FD and CV, respectively. A positive correlation between FD and CV (R=0.51, p<0.01 was found during the sustained 60% MVC, probably as a result of simultaneous motor unit synchronization and a decrease in muscle fiber CV during the fatiguing task.Central and peripheral fatigue can be described as changes in FD and CV, at least in young, healthy women. The significant correlation between FD and CV observed at 60% MVC suggests that a mutual interaction between central and peripheral fatigue can arise during submaximal isometric contractions.

  17. Quadriceps function following ACL reconstruction and rehabilitation : implications for optimisation of current practices

    NARCIS (Netherlands)

    Gokeler, Alli; Bisschop, Marsha; Benjaminse, Anne; Myer, Greg D.; Eppinga, Peter; Otten, Egbert

    2014-01-01

    To determine the most effective practices for quadriceps strengthening after ACL reconstruction. An electronic search has been performed for the literature appearing from January 1990 to January 2012. Inclusion criteria were articles written in English, German or Dutch with unilateral ACL-reconstruc

  18. Fatigue of intermittently stimulated quadriceps during imposed cyclical lower leg movements

    NARCIS (Netherlands)

    Franken, Henry M.; Veltink, Peter H.; Fidder, Marc; Boom, Herman B.K.

    1992-01-01

    During prolonged experiments the influence of knee angular velocity, and stimulation parameters (interpulse interval (IPI), duty cycle (DC), number of pulses per cycle (NP)) on fatigue-induced torque decline of paralyzed human quadriceps was studied. Identification of torque-angle and -angular veloc

  19. Percutaneous quadriceps tendon pie-crusting release of extension contracture of the knee.

    Science.gov (United States)

    Liu, H X; Wen, H; Hu, Y Z; Yu, H C; Pan, X Y

    2014-05-01

    To release extension contracture of the knee, the authors used a minimally invasive technique: percutaneous quadriceps tendon pie-crusting release. Percutaneous pie-crusting release was performed using an 18-gauge needle to puncture the stiff fibrous band of the distal and lateral quadriceps tendon under maximum knee flexion. Quadriceps contracture was gradually released by multiple needle punctures. A knee brace was prescribed for one week and knee flexion exercises were performed on the first postoperative day. This technique was performed in seven post-traumatic stiff knees and five stiff total knee arthroplasties. Mean maximum flexion increased from 37° preoperatively to 50° after arthrolysis and 107(o) after pie-crusting. At a mean follow-up of eight months, mean maximum flexion was 103°. There were no major complications. The technique of quadriceps tendon pie-crusting release is a simple, minimally invasive and effective treatment for knee extension contracture. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  20. Artificial-reflex stimulation for FES-induced standing with minimum quadriceps force

    NARCIS (Netherlands)

    Mulder, A.J.; Mulder, A.J.; Boom, H.B.K.; Hermens, Hermanus J.; Zilvold, G.; Zilvold, G.

    1990-01-01

    A control strategy is proposed to decrease quadriceps activity during standing. Modified on/off (or artificial reflex) control is used: a non-numerical or finite-state control scheme based on feedback of knee angle and angular velocity. The control strategy is evaluated in paraplegic patients in an

  1. Rapid Hamstrings/Quadriceps strength in ACL-reconstructed elite alpine ski racers

    DEFF Research Database (Denmark)

    Jordan, Matthew J; Aagaard, Per; Herzog, Walter

    2015-01-01

    PURPOSE: Due to the importance of hamstrings (HAM) and quadriceps (QUAD) strength for anterior cruciate ligament (ACL) injury prevention, and the high incidence of ACL injury in ski racing, HAM and QUAD maximal and explosive strength was assessed in ski racers with and without ACL reconstruction...

  2. Quadriceps Weakness, Patella Alta and Structural Features of Patellofemoral Osteoarthritis: The Multicenter Osteoarthritis Study

    Science.gov (United States)

    Stefanik, Joshua J.; Guermazi, Ali; Zhu, Yanyan; Zumwalt, Ann C.; Gross, K. Douglas; Clancy, Margaret; Lynch, John A.; Segal, Neil A.; Lewis, Cora E.; Roemer, Frank W.; Powers, Christopher M.; Felson, David T.

    2011-01-01

    Objective To determine the relationship between quadriceps weakness and cartilage damage and bone marrow lesions (BMLs) in the patellofemoral joint (PFJ), and if this relationship is modified by patella alta. Methods The Multicenter Osteoarthritis (MOST) Study is a cohort study of persons aged 50–79 years with or at risk for knee OA. Concentric knee extensor strength was measured using an isokinetic dynamometer. Patella alta was measured using the Insall-Salvati ratio (ISR) on the lateral radiograph, and cartilage damage and bone marrow lesions (BMLs) were graded on MRI in the PFJ. We determined the association between quadriceps weakness with cartilage damage and BMLs in the PFJ among those knees with (ISR≥1.2) and without patella alta (ISRpatella alta in the lateral PFJ. Conclusion Quadriceps weakness was associated with PFJ cartilage damage and BMLs. While both patella alta and quadriceps weakness are associated with PFJ damage, the combination of the two was not associated with more damage than either of these factors alone. PMID:21702087

  3. Mechanical muscle function, morphology, and fiber type in lifelong trained elderly

    DEFF Research Database (Denmark)

    Aagaard, Per; Magnusson, Peter S; Larsson, Benny

    2007-01-01

    PURPOSE: Maximal muscle contraction force and muscle mass are both reduced during the natural aging process. Long-term training may be used to attenuate this age-related loss in muscle function and muscle size. METHODS: Maximum isometric quadriceps strength (MVC), rate of force development (RFD......), and muscle fiber composition and size (CSA) were studied in elderly individuals (68-78 yr) chronically exposed (> 50 yr) to either endurance (E) or strength (S) training, and in age-matched, untrained (U) elderly group. RESULTS: E and S showed greater MVC than did U. Contractile RFD was elevated in S...

  4. Does vitamin-D intake during resistance training improve the skeletal muscle hypertrophic and strength response in young and elderly men? – a randomized controlled trial

    DEFF Research Database (Denmark)

    Agergaard, Jakob; Trøstrup, Jeanette; Uth, Jacob

    2015-01-01

    (December-April, 56°N). During the last 12 weeks of the supplementation the subjects underwent progressive resistance training of the quadriceps muscle. Muscle hypertrophy, measured as changes in cross sectional area (CSA), and isometric strength of the quadriceps were determined. Muscle biopsies were...... compared to the placebo group (p = 0.006). Neither resistance training nor vitamin-D intake changed VDR mRNA expression. CONCLUSION: No additive effect of vitamin-D intake during 12 weeks of resistance training could be detected on either whole muscle hypertrophy or muscle strength, but improved muscle......INTRODUCTION: Recent studies have shown that vitamin-D intake can improve skeletal muscle function and strength in frail vitamin-D insufficient individuals. We investigated whether vitamin-D intake can improve the muscular response to resistance training in healthy young and elderly individuals...

  5. Pain level after ACL reconstruction: A comparative study between free quadriceps tendon and hamstring tendons autografts.

    Science.gov (United States)

    Buescu, Cristian Tudor; Onutu, Adela Hilda; Lucaciu, Dan Osvald; Todor, Adrian

    2017-03-01

    The objective of this study was to compare the pain levels and analgesic consumption after single bundle ACL reconstruction with free quadriceps tendon autograft versus hamstring tendon autograft. A total of 48 patients scheduled for anatomic single-bundle ACL reconstruction were randomized into two groups: the free quadriceps tendon autograft group (24 patients) and the hamstring tendons autograft group (24 patients). A basic multimodal analgesic postoperative program was used for all patients and rescue analgesia was provided with tramadol, at pain scores over 30 on the Visual Analog Scale. The time to the first rescue analgesic, the number of doses of tramadol and pain scores were recorded. The results within the same group were compared with the Wilcoxon signed test. Supplementary analgesic drug administration proved significantly higher in the group of subjects with hamstring grafts, with a median (interquartile range) of 1 (1.3) dose, compared to the group of subjects treated with a quadriceps graft, median = 0.5 (0.1.25) (p = 0.009). A significantly higher number of subjects with a quadriceps graft did not require any supplementary analgesic drug (50%) as compared with subjects with hamstring graft (13%; Z-statistics = 3.01, p = 0.002). The percentage of subjects who required a supplementary analgesic drug was 38% higher in the HT group compared with the FQT group. The use of the free quadriceps tendon autograft for ACL reconstruction leads to less pain and analgesic consumption in the immediate postoperative period compared with the use of hamstrings autograft. Level I Therapeutic study. Copyright © 2017 Turkish Association of Orthopaedics and Traumatology. Production and hosting by Elsevier B.V. All rights reserved.

  6. Rapid recovery from spontaneous and simultaneous bilateral quadriceps tendon rupture in an active, healthy individual.

    Science.gov (United States)

    Gaheer, Rajinder Singh; Hawkins, Amanda

    2010-07-13

    Bilateral spontaneous quadriceps rupture is an uncommon injury that is usually seen in association with multiple medical conditions and is frequently misdiagnosed. It is rarely seen in healthy, active individuals. This article presents a case of bilateral simultaneous and spontaneous rupture of the quadriceps tendon in a healthy, athletic, active and highly motivated patient with rapid recovery from injury and return to full sport activity within a relatively short period of time. A 65-year-old healthy man felt both knees give way while walking down stairs at home and collapsed, unable to bear weight. He was fit and well, not on any medications and basic laboratory screening was within normal limits. He was an active sportsman, horse rider, swimmer, and long-distance cyclist, and had completed a half marathon 1 month before his injury. He was diagnosed with bilateral quadriceps tendon ruptures. An ultrasound of both knees confirmed the diagnosis of full-thickness rupture. Surgical repair of both quadriceps tendons was performed 3 days after the injury. Bilateral locking brace in 10 degrees of flexion was used to immobilize both knees and protect the repair for 6 weeks. The patient remained nonweight bearing for 2 weeks, then gradual weight bearing was commenced, with full weight bearing at 6 weeks. Intensive isometric quadriceps exercises were started on the second postoperative day. Immobilization of both knees was maintained for 6 weeks, after which full active range of motion (ROM) was initiated. At 16 weeks after the injury he had bilateral ROM from 0 degrees to 120 degrees flexion, with no extension lag. He was horse riding, playing golf, swimming, and walking distances up to 2 miles at that time.

  7. Agonist muscle activity and antagonist muscle co-activity levels during standardized isotonic and isokinetic knee extensions.

    Science.gov (United States)

    Remaud, Anthony; Cornu, Christophe; Guével, Arnaud

    2009-06-01

    This study aimed to analyze the effects of the contraction mode (isotonic vs. isokinetic concentric conditions), the joint angle and the investigated muscle on agonist muscle activity and antagonist muscle co-activity during standardized knee extensions. Twelve healthy adult subjects performed three sets of isotonic knee extensions at 40% of their maximal voluntary isometric torque followed by three sets of maximal isokinetic knee extensions on an isokinetic dynamometer. For each set, the mean angular velocity and the total external amount of work performed were standardized during the two contraction modes. Surface electromyographic activity of vastus lateralis (VL), vastus medialis (VM), rectus femoris (RF), semitendinosus (ST) and biceps femoris (BF) muscles was recorded. Root mean square values were then calculated for each 10 degrees between 85 degrees and 45 degrees of knee extension (0 degrees =horizontal position). Results show that agonist muscle activity and antagonist muscle co-activity levels are significantly greater in isotonic mode compared to isokinetic mode. Quadriceps activity and hamstrings co-activity are significantly lower at knee extended position in both contraction modes. Considering agonist muscles, VL reveals a specific pattern of activity compared to VM and RF; whereas considering hamstring muscles, BF shows a significantly higher co-activity than ST in both contraction modes. Results of this study confirmed our hypothesis that higher quadriceps activity is required during isotonic movements compared to isokinetic movements leading to a higher hamstrings co-activity.

  8. The association between submaximal quadriceps force steadiness and the knee adduction moment during walking in patients with knee osteoarthritis

    DEFF Research Database (Denmark)

    Sørensen, Tina Juul; Langberg, Henning; Aaboe, Jens

    2011-01-01

    STUDY DESIGN: Cross-sectional study. OBJECTIVES: To investigate the relationship between quadriceps force steadiness and knee adduction moment during walking in patients with knee osteoarthritis (OA). BACKGROUND: Studies have shown that quadriceps force steadiness is impaired in patients with knee......, and knee pain was assessed using the Knee Injury and Osteoarthritis Outcome Score (KOOS) pain subscale and a visual analog scale. RESULTS: Regression analyses showed that quadriceps force steadiness did not predict the peak knee adduction moment (adjusted R2 = 0.05, P = .41). Inclusion of covariates did...

  9. STRUCTURAL ALTERATIONS OF SKELETAL MUSCLE IN COPD

    Directory of Open Access Journals (Sweden)

    Sunita eMathur

    2014-03-01

    Full Text Available Background: Chronic obstructive pulmonary disease (COPD is a respiratory disease associated with a systemic inflammatory response. Peripheral muscle dysfunction has been well characterized in individuals with COPD and results from a complex interaction between systemic and local factors. Objective: In this narrative review, we will describe muscle wasting in people with COPD, the associated structural changes, muscle regenerative capacity and possible mechanisms for muscle wasting. We will also discuss how structural changes relate to impaired muscle function and mobility in people with COPD. Key Observations: Approximately 30-40% of individuals with COPD experience muscle mass depletion. Furthermore, muscle atrophy is a predictor of physical function and mortality in this population. Associated structural changes include a decreased proportion and size of type-I fibers, reduced oxidative capacity and mitochondrial density mainly in the quadriceps. Observations related to impaired muscle regenerative capacity in individuals with COPD include a lower proportion of central nuclei in the presence or absence of muscle atrophy and decreased maximal telomere length, which has been correlated with reduced muscle cross-sectional area. Potential mechanisms for muscle wasting in COPD may include excessive production of reactive oxygen species, altered amino acid metabolism and lower expression of peroxisome proliferator-activated receptors-gamma-coactivator 1-alpha mRNA. Despite a moderate relationship between muscle atrophy and function, impairments in oxidative metabolism only seems weakly related to muscle function. Conclusion: This review article demonstrates the cellular modifications in the peripheral muscle of people with COPD and describes the evidence of its relationship to muscle function. Future research will focus on rehabilitation strategies to improve muscle wasting and maximize function.

  10. The alterations in adenosine nucleotides and lactic acid levels in striated muscles following death with cervical dislocation or electric shock.

    Science.gov (United States)

    Pençe, Halime Hanim; Pençe, Sadrettin; Kurtul, Naciye; Bakan, Ebubekir; Kök, Ahmet Nezih; Kocoglu, Hasan

    2003-01-01

    In this study, changes in adenosine triphosphate (ATP), adenosine diphosphate (ADP), adenosine monophosphate (AMP) and lactic acid levels in masseter, triceps, and quadriceps muscles obtained from right and left sides of Spraque-Dawley rats following two different types of death were investigated. The samples were taken immediately and 120 minutes after death occurred either by cervical dislocation or electric shock. ATP concentrations in the muscles of masseter, triceps, and quadriceps were lower in samples obtained 120 minutes after death than that of samples obtained immediately after death. ADP, AMP, and lactic acid concentrations in these muscles were higher in samples obtained 120 minutes after death than those obtained immediately after death. A positive linear correlation was determined between ATP and ADP concentrations in quadriceps muscles of the rats killed with cervical dislocation and in masseter muscles of the rats killed with electric shock. When the rats killed with cervical dislocation and with electric shock were compared, ADP, AMP, and lactic acid concentrations were lower in the former than in the latter for both times (immediately and 120 minutes after death occurred). In the case of electric shock, ATP is consumed faster because of immediate contractions during death, resulting in a faster rigor mortis. This finding was confirmed with higher lactic acid levels in muscles of the rats killed with electric shock than the other group. In the cervical dislocation and electric shock group rats, ATP decreased in different levels in the three different muscle types mentioned above, being much decline in masseter in cervical dislocation and in quadriceps in electric shock group. This may be caused by low mass and less glycogen storage of masseter and by near localisation of electrode to quadriceps. One can conclude that the occurrence of rigor mortis is closely related to the mode of death.

  11. Muscle morphology and metabolism in hypothyroid myopathy: effects of treatment.

    OpenAIRE

    1983-01-01

    Needle biopsies from vastus lateralis in untreated hypothyroid patients with muscle weakness confirmed by quadriceps force measurements (n = 11) were repeated when the patients had taken L-thyroxine for a mean period of 9.2 months (range 5.3-13.3 months, n = 8) and had been continuously biochemically euthyroid for a mean period of 4.9 months (range 2-11 months). Biopsies were analysed biochemically for mitochondrial function. On light microscopy, histochemical examination, mean fibre areas an...

  12. Lower limb muscle strength is associated with functional performance and quality of life in patients with systemic sclerosis

    Directory of Open Access Journals (Sweden)

    Tatiana R. L. Lima

    2015-04-01

    Full Text Available Background: Complaints of peripheral muscle weakness are quite common in patients with systemic sclerosis (SSc. It is likely that the muscle impairments may reduce the patients' exercise performance, which in turn may decrease their functional capacity and exert a direct impact on their quality of life. Objectives: To assess the peripheral and respiratory muscle strength in individuals with SSc and to investigate their correlation with the 6-min walk distance (6MWD and quality of life measurements. Moreover, we aimed to characterize their nutritional status, pulmonary function, functional capacity, and quality of life compared to the controls. Method: The present cross-sectional study included 20 patients with SSc and 20 control subjects. All of the participants were subjected to isometric dynamometry, surface electromyography, bioelectrical impedance analysis, pulmonary function testing, and the 6-min walk test. Patients with SSc also responded to the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36 and the Health Assessment Questionnaire Disability Index (HAQ-DI. Results: The individuals with SSc exhibited a reduction in quadriceps strength (p=0.0001, increased quadriceps fatigability (p=0.034, impaired pulmonary function, and a reduced 6MWD (p=0.0001 compared to the controls. Quadriceps strength was significantly correlated with the 6MWD (Rho=0.719; p=0.0004 and the HAQ-DI (Rho=-0.622; p=0.003. We also found significant correlations between quadriceps fatigability and maximal inspiratory (Rho=0.684; p=0.0009 and maximal expiratory (Rho=0.472; p=0.035 pressure. Conclusions: Patients with SSc exhibited reduced respiratory muscle and quadriceps strength and an increase in its fatigability. In these individuals, there was a relationship between quadriceps strength, functional capacity, and quality of life.

  13. ALTERATION OF MUSCLE FUNCTION AFTER ELECTRICAL STIMULATION BOUT OF KNEE EXTENSORS AND FLEXORS

    Directory of Open Access Journals (Sweden)

    Marc Vanderthommen

    2012-12-01

    Full Text Available The purpose was to study the effects on muscle function of an electrical stimulation bout applied unilaterally on thigh muscles in healthy male volunteers. One group (ES group, n = 10 received consecutively 100 isometric contractions of quadriceps and 100 isometric contractions of hamstrings (on-off ratio 6-6 s induced by neuromuscular electrical stimulations (NMES. Changes in muscle torque, muscle soreness (0-10 VAS, muscle stiffness and serum creatine kinase (CK activity were assessed before the NMES exercise (pre-ex as well as 24h (d+1, 48h (d+2 and 120h (d+5 after the bout. A second group (control group, n = 10 were submitted to the same test battery than the ES group and with the same time-frame. The between-group comparison indicated a significant increase in VAS scores and in serum levels of CK only in the ES group. In the ES group, changes were more pronounced in hamstrings than in quadriceps and peaked at d+2 (quadriceps VAS scores = 2.20 ± 1.55 a.u. (0 at pre-ex; hamstrings VAS scores = 3.15 ± 2.14 a.u. (0 at pre-ex; hip flexion angle = 62 ± 5° (75 ± 6° at pre-ex; CK activity = 3021 ± 2693 IU·l-1 (136 ± 50 IU·l-1 at pre-ex. The results of the present study suggested the occurrence of muscle damage that could have been induced by the peculiar muscle recruitment in NMES and the resulting overrated mechanical stress. The sensitivity to the damaging effects of NMES appeared higher in the hamstrings than in quadriceps muscles

  14. Comparison of Three Methods of Assessing Muscle Strength and Imbalance Ratios of the Knee

    OpenAIRE

    Moss, Crayton L.; Wright, P. Thomas

    1993-01-01

    Three strength measurement methods for determining muscle strength and imbalance ratios of the knee were compared in 41 (23 female, 18 male) NCAA Division I track and field athletes. Peak quadriceps extensions and hamstring flexions were measured isotonically, isometrically, and isokinetically. Isokinetic measurements were performed on a Cybex II at 60°/s. Isometric extension and flexion measurements were performed using the Nicholas Manual Muscle Tester (Lafayette Instruments; Lafayette, Ind...

  15. Mechanisms of cisplatin-induced muscle atrophy

    Energy Technology Data Exchange (ETDEWEB)

    Sakai, Hiroyasu, E-mail: sakai@hoshi.ac.jp [Department of Pharmacology, Hoshi University, 2-4-41 Ebara, Shinagawa-ku, Tokyo 1428501 (Japan); Division of Pharmacy Professional Development and Research, Hoshi University, 2-4-41 Ebara, Shinagawa-ku, Tokyo 1428501 (Japan); Sagara, Atsunobu; Arakawa, Kazuhiko; Sugiyama, Ryoto; Hirosaki, Akiko; Takase, Kazuhide; Jo, Ara [Department of Pharmacology, Hoshi University, 2-4-41 Ebara, Shinagawa-ku, Tokyo 1428501 (Japan); Sato, Ken [Department of Pharmacology, Hoshi University, 2-4-41 Ebara, Shinagawa-ku, Tokyo 1428501 (Japan); Division of Pharmacy Professional Development and Research, Hoshi University, 2-4-41 Ebara, Shinagawa-ku, Tokyo 1428501 (Japan); Chiba, Yoshihiko [Department of Biology, Hoshi University, 2-4-41 Ebara, Shinagawa-ku, Tokyo 1428501 (Japan); Yamazaki, Mitsuaki [Department of Anesthesiology, Graduate School of Medicine and Pharmaceutical Sciences for Research, University of Toyama, 2630 Sugitani, Toyama-shi, Toyama 9300194 (Japan); Matoba, Motohiro [Department of Palliative Medicine and Psychooncology, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 1040045 (Japan); Narita, Minoru, E-mail: narita@hoshi.ac.jp [Department of Pharmacology, Hoshi University, 2-4-41 Ebara, Shinagawa-ku, Tokyo 1428501 (Japan)

    2014-07-15

    Fatigue is the most common side effect of chemotherapy. However, the mechanisms of “muscle fatigue” induced by anti-cancer drugs are not fully understood. We therefore investigated the muscle-atrophic effect of cisplatin, a platinum-based anti-cancer drug, in mice. C57BL/6J mice were treated with cisplatin (3 mg/kg, i.p.) or saline for 4 consecutive days. On Day 5, hindlimb and quadriceps muscles were isolated from mice. The loss of body weight and food intake under the administration of cisplatin was the same as those in a dietary restriction (DR) group. Under the present conditions, the administration of cisplatin significantly decreased not only the muscle mass of the hindlimb and quadriceps but also the myofiber diameter, compared to those in the DR group. The mRNA expression levels of muscle atrophy F-box (MAFbx), muscle RING finger-1 (MuRF1) and forkhead box O3 (FOXO3) were significantly and further increased by cisplatin treated group, compared to DR. Furthermore, the mRNA levels of myostatin and p21 were significantly upregulated by the administration of cisplatin, compared to DR. On the other hand, the phosphorylation of Akt and FOXO3a, which leads to the blockade of the upregulation of MuRF1 and MAFbx, was significantly and dramatically decreased by cisplatin. These findings suggest that the administration of cisplatin increases atrophic gene expression, and may lead to an imbalance between protein synthesis and protein degradation pathways, which would lead to muscle atrophy. This phenomenon could, at least in part, explain the mechanism of cisplatin-induced muscle fatigue. - Highlights: • Cisplatin decreased mass and myofiber diameter in quadriceps muscle. • The mRNA of MAFbx, MuRF1 and FOXO3 were increased by the cisplatin. • The mRNA of myostatin and p21 were upregulated by cisplatin. • The phosphorylation of Akt and FOXO3a was decreased by cisplatin.

  16. The effect of passive stretching on delayed onset muscle soreness, and other detrimental effects following eccentric exercise

    DEFF Research Database (Denmark)

    Lund, Henrik; Vestergaard-Poulsen, P; Kanstrup, I.L.

    1998-01-01

    The aim of this study was to measure if passive stretching would influence delayed onset muscle soreness (DOMS), dynamic muscle strength, plasma creatine kinase concentration (CK) and the ratio of phosphocreatine to inorganic phosphate (PCr/P(i)) following eccentric exercise. Seven healthy......, CK and muscle pain were measured before the eccentric exercise (day 0) and the following 7 d. In the second experiment daily passive stretching (3 times of 30 s duration, with a pause of 30 s in between) of m. quadriceps was included in the protocol. The stretching was performed before...... subjects reported pain in the right m. quadriceps with a peak 48 h after exercise. There was no difference in the reported variables between experiments one and two. It is concluded that passive stretching did not have any significant influence on increased plasma-CK, muscle pain, muscle strength...

  17. ACUTE EFFECTS OF DIFFERENT STATIC STRETCHING PROTOCOLS ON PEAK TORQUE, CONVENTIONAL AND FUNCTIONAL HAMSTRINGS-TO-QUADRICEPS RATIOS IN ACTIVE WOMEN

    Directory of Open Access Journals (Sweden)

    Ghada M. ALQaslah

    2016-10-01

    Full Text Available Background: This study might have been directed to some degree because of clashing results in the past studies regarding the impacts for different SS protocols on muscle strength and possibility for injury. The objective of the study was to investigate the acute effects of different static stretching (SS durations (20, 30, and 60s on isokinetic concentric quadriceps (Q and hamstrings (H peak torque (PT, eccentric H PT and conventional and functional H:Q ratios under different stretching conditions and angular velocities (60°and180°/s in active women. Methods: Isokinetic tests were performed on 108 active women. A HUMAC system was used to measure unilateral concentric Q and H PT, and eccentric H PT at 60 and 180º/s at baseline and after a bout of H-only, Q-only, and combined H and Q muscles SS. The data were statistically treated using five separate three-way (time x conditions x velocity ANOVA. Results: There were no significant differences among groups at baseline (P > 0.05. Significant reductions of all outcome measures have been shown to occur after 30 and 60s of SS (P 0.05. Conclusion: Short-lasting stretching can be done before exercises that require strength. However, since 30s or 60s stretching protocols adversely affect the muscle strength, performance and lower H:Q ratios they are not recommended prior to activities demanding the production of high forces.

  18. Epigenetic regulation of muscle phenotype and adaptation: a potential role in COPD muscle dysfunction.

    Science.gov (United States)

    Barreiro, Esther; Sznajder, Jacob I

    2013-05-01

    Quadriceps muscle dysfunction occurs in one-third of patients with chronic obstructive pulmonary disease (COPD) in very early stages of their condition, even prior to the development of airway obstruction. Among several factors, deconditioning and muscle mass loss are the most relevant contributing factors leading to this dysfunction. Moreover, epigenetics, defined as the process whereby gene expression is regulated by heritable mechanisms that do not affect DNA sequence, could be involved in the susceptibility to muscle dysfunction, pathogenesis, and progression. Herein, we review the role of epigenetic mechanisms in muscle development and adaptation to environmental factors such as immobilization and exercise, and their implications in the pathophysiology and susceptibility to muscle dysfunction in COPD. The epigenetic modifications identified so far include DNA methylation, histone acetylation and methylation, and non-coding RNAs such as microRNAs (miRNAs). In the present review, we describe the specific contribution of epigenetic mechanisms to the regulation of embryonic myogenesis, muscle structure and metabolism, immobilization, and exercise, and in muscles of COPD patients. Events related to muscle development and regeneration and the response to exercise and immobilization are tightly regulated by epigenetic mechanisms. These environmental factors play a key role in the outcome of muscle mass and function as well as in the susceptibility to muscle dysfunction in COPD. Future research remains to be done to shed light on the specific target pathways of miRNA function and other epigenetic mechanisms in the susceptibility, pathogenesis, and progression of COPD muscle dysfunction.

  19. Changes in Predicted Muscle Coordination with Subject-Specific Muscle Parameters for Individuals after Stroke

    Directory of Open Access Journals (Sweden)

    Brian A. Knarr

    2014-01-01

    Full Text Available Muscle weakness is commonly seen in individuals after stroke, characterized by lower forces during a maximal volitional contraction. Accurate quantification of muscle weakness is paramount when evaluating individual performance and response to after stroke rehabilitation. The objective of this study was to examine the effect of subject-specific muscle force and activation deficits on predicted muscle coordination when using musculoskeletal models for individuals after stroke. Maximum force generating ability and central activation ratio of the paretic plantar flexors, dorsiflexors, and quadriceps muscle groups were obtained using burst superimposition for four individuals after stroke with a range of walking speeds. Two models were created per subject: one with generic and one with subject-specific activation and maximum isometric force parameters. The inclusion of subject-specific muscle data resulted in changes in the model-predicted muscle forces and activations which agree with previously reported compensation patterns and match more closely the timing of electromyography for the plantar flexor and hamstring muscles. This was the first study to create musculoskeletal simulations of individuals after stroke with subject-specific muscle force and activation data. The results of this study suggest that subject-specific muscle force and activation data enhance the ability of musculoskeletal simulations to accurately predict muscle coordination in individuals after stroke.

  20. The embryonic genes Dkk3, Hoxd8, Hoxd9 and Tbx1 identify muscle types in a diet-independent and fiber-type unrelated way

    Directory of Open Access Journals (Sweden)

    Boekschoten Mark V

    2010-03-01

    Full Text Available Abstract Background The mouse skeletal muscle is composed of four distinct fiber types that differ in contractile function, number of mitochondria and metabolism. Every muscle type has a specific composition and distribution of the four fiber types. To find novel genes involved in specifying muscle types, we used microarray analysis to compare the gastrocnemius with the quadriceps from mice fed a low fat diet (LFD or high fat diet (HFD for 8 weeks. Additional qPCR analysis were performed in the gastrocnemius, quadriceps and soleus muscle from mice fed an LFD or HFD for 20 weeks. Results In mice fed the 8-week LFD 162 genes were differentially expressed in the gastrocnemius vs. the quadriceps. Genes with the strongest differences in expression were markers for oxidative fiber types (e.g. Tnni1 and genes which are known to be involved in embryogenesis (Dkk3, Hoxd8,Hoxd9 and Tbx1. Also Dkk2, Hoxa5, Hoxa10, Hoxc9, Hoxc10, Hoxc6 and Tbx15 were detectably, but not differentially expressed in adult muscle tissue. Expression of differentially expressed genes was not influenced by an 8-week or 20-week HFD. Comparing gastrocnemius, quadriceps and soleus, expression of Hoxd8 and Hoxd9 was not related with expression of markers for the four different fiber types. We found that the expression of both Hoxd8 and Hoxd9 was much higher in the gastrocnemius than in the quadriceps or soleus, whereas the expression of Dkk3 was high in quadriceps, but low in both gastrocnemius and soleus. Finally, expression of Tbx1 was high in quadriceps, intermediate in soleus and low in gastrocnemius. Conclusions We found that genes from the Dkk family, Hox family and Tbx family are detectably expressed in adult mouse muscle. Interestingly, expression of Dkk3, Hoxd8, Hoxd9 and Tbx1 was highly different between gastrocnemius, quadriceps and soleus. In fact, every muscle type showed a unique combination of expression of these four genes which was not influenced by diet. Altogether

  1. Knee Muscle Forces during Walking and Running in Patellofemoral Pain Patients and Pain-Free Controls

    Science.gov (United States)

    Besier, Thor F.; Fredericson, Michael; Gold, Garry E.; Beaupré, Gary S.; Delp, Scott L.

    2009-01-01

    One proposed mechanism of patellofemoral pain, increased stress in the joint, is dependent on forces generated by the quadriceps muscles. Describing causal relationships between muscle forces, tissue stresses, and pain is difficult due to the inability to directly measure these variables in vivo. The purpose of this study was to estimate quadriceps forces during walking and running in a group of male and female patients with patellofemoral pain (n=27, 16 female; 11 male) and compare these to pain-free controls (n=16, 8 female; 8 male). Subjects walked and ran at self-selected speeds in a gait laboratory. Lower limb kinematics and electromyography (EMG) data were input to an EMG-driven musculoskeletal model of the knee, which was scaled and calibrated to each individual to estimate forces in 10 muscles surrounding the joint. Compared to controls, the patellofemoral pain group had greater co-contraction of quadriceps and hamstrings (p=0.025) and greater normalized muscle forces during walking, even though the net knee moment was similar between groups. Muscle forces during running were similar between groups, but the net knee extension moment was less in the patellofemoral pain group compared to controls. Females displayed 30-50% greater normalized hamstring and gastrocnemius muscle forces during both walking and running compared to males (pjoint contact forces and joint stresses than pain-free subjects. PMID:19268945

  2. Acute femoral neuropathy secondary to an iliacus muscle hematoma.

    Science.gov (United States)

    Seijo-Martínez, M; Castro del Río, M; Fontoira, E; Fontoira, M

    2003-05-15

    We present a patient with a spontaneous iliacus muscle hematoma, appearing immediately after a minor physical maneuver, presenting with pain and femoral neuropathy initially evidenced by massive quadriceps muscle fasciculations. A magnetic resonance imaging (MRI) study of the pelvic area confirmed the diagnosis, showing a hematoma secondary to a partial muscle tear. The patient was managed conservatively, and the continuous muscle activity ceased in 3 days, with progressive improvement of the pain and weakness. The recovery was complete. Femoral neuropathy is uncommon and usually due to compression from psoas muscle mass lesions of diverse nature, including hematomas. Usually subacute, femoral neuropathy may present acutely in cases of large or strategically placed compressive femoral nerve lesions, and may require surgical evacuation. The case presented herein is remarkable since the muscle hematoma appeared after a nonviolent maneuver, fasciculations were present at onset, and conservative management was sufficient for a full recovery.

  3. Isokinetic concentric quadriceps and hamstring normative data for elite collegiate American football players participating in the NFL Scouting Combine.

    Science.gov (United States)

    Zvijac, John E; Toriscelli, Todd A; Merrick, W Shannon; Papp, Derek F; Kiebzak, Gary M

    2014-04-01

    Isokinetic concentric quadriceps and hamstring strength data using a Cybex dynamometer are collected for elite collegiate American football players invited to the annual National Football League Scouting Combine. We constructed a normative (reference) database of the Cybex strength data for the purpose of allowing comparison of an individual's values to his peers. Data reduction was performed to construct frequency distributions of hamstring/quadriceps (H/Q) ratios and side-to-side strength differences. For the cohort (n = 1,252 players), a statistically significant but very small (1.9%) mean quadriceps strength preference existed for dominant side vs. nondominant side. Peak torque (Newton meters, best repetition) for quadriceps and hamstrings was significantly correlated to player body mass (weight) (the same relationship was found for other variables using peak torque in the calculation). Peak torque varied by player position, being greatest for offensive linemen and lowest for kickers (p 10% are common, not the exception.

  4. Muscle Metabolic Responses During Dynamic In-Magnet Exercise Testing : A Pilot Study in Children with an Idiopathic Inflammatory Myopathy

    NARCIS (Netherlands)

    van Brussel, Marco; van Oorschot, Joep W. M.; Schmitz, Joep P. J.; Nicolay, Klaas; van Royen-Kerkhof, Annet; Takken, Tim; Jeneson, Jeroen A. L.

    2015-01-01

    Rationale and Objectives: The clinical utility of supine in-magnet bicycling in combination with phosphorus magnetic resonance spectroscopy (P-31 MRS) to evaluate quadriceps muscle metabolism was examined in four children with juvenile dermatomyositis (JDM) in remission and healthy age- and gender-m

  5. Muscle Metabolic Responses During Dynamic In-Magnet Exercise Testing : A Pilot Study in Children with an Idiopathic Inflammatory Myopathy

    NARCIS (Netherlands)

    van Brussel, Marco; van Oorschot, Joep W M; Schmitz, Joep P J; Nicolay, Klaas; van Royen-Kerkhof, A; Takken, Tim; Jeneson, Jeroen A L

    2015-01-01

    Rationale and Objectives: The clinical utility of supine in-magnet bicycling in combination with phosphorus magnetic resonance spectroscopy (31P MRS) to evaluate quadriceps muscle metabolism was examined in four children with juvenile dermatomyositis (JDM) in remission and healthy age- and gender-ma

  6. Muscle Metabolic Responses During Dynamic In-Magnet Exercise Testing : A Pilot Study in Children with an Idiopathic Inflammatory Myopathy

    NARCIS (Netherlands)

    van Brussel, Marco; van Oorschot, Joep W. M.; Schmitz, Joep P. J.; Nicolay, Klaas; van Royen-Kerkhof, Annet; Takken, Tim; Jeneson, Jeroen A. L.

    2015-01-01

    Rationale and Objectives: The clinical utility of supine in-magnet bicycling in combination with phosphorus magnetic resonance spectroscopy (P-31 MRS) to evaluate quadriceps muscle metabolism was examined in four children with juvenile dermatomyositis (JDM) in remission and healthy age- and gender-m

  7. Muscle Metabolic Responses During Dynamic In-Magnet Exercise Testing : A Pilot Study in Children with an Idiopathic Inflammatory Myopathy

    NARCIS (Netherlands)

    van Brussel, Marco|info:eu-repo/dai/nl/30481962X; van Oorschot, Joep W M; Schmitz, Joep P J; Nicolay, Klaas; van Royen-Kerkhof, A|info:eu-repo/dai/nl/288270770; Takken, Tim|info:eu-repo/dai/nl/184586674; Jeneson, Jeroen A L

    2015-01-01

    Rationale and Objectives: The clinical utility of supine in-magnet bicycling in combination with phosphorus magnetic resonance spectroscopy (31P MRS) to evaluate quadriceps muscle metabolism was examined in four children with juvenile dermatomyositis (JDM) in remission and healthy age- and gender-ma

  8. Effects of ibuprofen on exercise-induced muscle soreness and indices of muscle damage.

    Science.gov (United States)

    Donnelly, A E; Maughan, R J; Whiting, P H

    1990-01-01

    Thirty-two volunteers participated in a two-period crossover study in which ibuprofen was tested against an identical placebo for its effectiveness in reducing muscle soreness and damage after two bouts of downhill running. Subjective soreness, quadriceps isometric strength and isometric endurance time at 50 percent of maximum strength, serum activities of creatine kinase, lactate dehydrogenase and aspartate transaminase and serum levels of creatinine and urea were recorded at intervals up to 72 hours after exercise. Each downhill run produced muscle soreness, and a decline in muscle strength and 50 percent endurance time, although these parameters were unaffected by ibuprofen treatment. All serum parameters measured increased after both runs, but for the three enzymes this increase was smaller after the second run. Serum creatine kinase and urea levels were higher in the ibuprofen group after both runs. These results indicate that ibuprofen is not an appropriate treatment for delayed onset muscle soreness and damage. PMID:2078806

  9. Surgical management of acute quadriceps tendon rupture (a case report with literature review).

    Science.gov (United States)

    Ennaciri, Badr; Montbarbon, Eric; Beaudouin, Emmanuel

    2015-01-01

    Quadriceps tendon rupture is uncommon and often overlooked in emergency. Tearing affects weakening tendon by systemic diseases or some medications. The mechanism is generally indirect. Inability to actively extend the knee associated to a supra-patellar defect evoke easily the diagnosis without other investigations. Surgical repair is realized in emergency to completely restore the extension. We report a case of a patient who has sustained of complete quadriceps tendon tear after a long period of tendon weakening by statin therapy, hypertension and diabetes. The repair has consisted on end-to-end Krackow sutures associated with bone suture to the proximal pole of the patella. Surgeons and emergency physicians must think to this form of extensor apparatus rupture, because early diagnosis leads to early treatment and to best outcomes.

  10. Foraging activity rhythms of Dinoponera quadriceps (Hymenoptera: Formicidae) in its natural environment.

    Science.gov (United States)

    Medeiros, Jeniffer; Azevedo, Dina L O; Santana, Melquisedec A D; Lopes, Talita R P; Araújo, Arrilton

    2014-01-01

    This study characterizes the foraging activity of the queenless ant Dinoponera quadriceps (Kempf) (Hymenoptera: Formicidae) in its natural environment by testing the hypotheses that foraging activity presents both daily and seasonal rhythmic variations, and that these rhythms are related to environmental variables. Four colonies of D. quadriceps were observed in an area of secondary Atlantic forest in northeastern Brazil. Data collection was performed over 72 h every three months during an annual cycle. Both daily and seasonal foraging activity rhythms of D. quadriceps colonies were related to environmental factors, but colony differences also explained part of foraging variations. Foraging activity of D. quadriceps colonies was predominantly diurnal independently of season. In the early dry season, the colonies had two activity peaks, one in the morning and another in the afternoon, with a decrease in foraging at midday; however, during the rest of the year, foraging activity was distributed more evenly throughout the daylight hours. The daily rhythm of foraging activity was likely determined by an endogenous circadian rhythm year-round, but in the dry season, temperature and relative humidity also influenced daily foraging activity, with a negative effect of temperature and a positive effect of relative humidity. On a seasonal scale, foraging activity peaked in the early dry season and suddenly declined at the end of this season, increasing again at the late rainy season. The seasonal rhythm of foraging was negatively related to relative humidity and positively related to prey availability. © The Author 2014. Published by Oxford University Press on behalf of the Entomological Society of America.

  11. Inflammatory cytokine expression in the quadriceps of rats with posttraumatic knee stiffness: A preliminary study.

    Science.gov (United States)

    Liu, Kemin; Wang, Fei; Cui, Zhigang; Liu, Sihai; Han, Xinzuo

    2015-06-01

    The primary purpose of this study was to investigate cytokine expression in the quadriceps of rats with posttraumatic knee stiffness (PTKS) and to determine the effect of exercise training on these cytokines at different follow-up time points. The PTKS rats were randomly assigned into two even groups. The treatment group received exercise training, while the control group received no treatment. Quadriceps specimens were harvested randomly from each group at 8, 12, 16, and 20 weeks. RT-qPCR and immunohistochemical analyses were used to assess the protein and mRNA expression levels of the cytokines IL-1, IL-2, TNF-α, COX-1, and COX-2. TNF-α immunostaining did not differ between the treated and control group tissues, whereas weak immunostaining was observed for all other cytokines in the specimens from the treatment group compared with those from the control group at approximately 12 and 20 weeks. The cytokine levels decreased at approximately 8 weeks in the treatment group, whereas these levels remained elevated or plateaued in the control group. These differences were statistically significant (pcytokines IL-1, IL-2, COX-1, and COX-2 increased in the quadriceps of rats with PTKS and that exercise training affected the observed profile trends of these cytokines.

  12. [Bilateral quadriceps tendon rupture and coexistent femoral neck fracture in a patient with chronic renal failure].

    Science.gov (United States)

    Kazimoğlu, Cemal; Yağdi, Serhan; Karapinar, Hasan; Sener, Muhittin

    2007-01-01

    Simultaneous bilateral quadriceps tendon rupture is a very rare injury mostly seen in patients with chronic renal failure or other systemic chronic diseases. Metabolic acidosis in chronic renal failure predisposes these patients to tendon degeneration. A 37-year-old woman who received hemodialysis for chronic renal failure for two years presented with complaints of severe pain in the left hip and inability to walk. She had a history of two consecutive falls in the past two months. On physical examination, there were joint spaces in both suprapatellar areas, active extension of both knees was inhibited, and movements of the left hip were quite painful. Knee ultrasonography and magnetic resonance imaging showed bilateral quadriceps tendon rupture from patellar attachment. At surgery, full-thickness quadriceps tendon tears were repaired with Tycron transpatellar suture anchors. Internal fixation was not considered for hip fracture due to the presence of chronic renal failure, so hemiarthroplasty with bipolar endoprosthesis was performed in the same session for femoral neck fracture. Six months after the operation, the patient was able to walk without support and almost regained her normal knee functions.

  13. Muscle reflexes during gait elicited by electrical stimulation of the posterior cruciate ligament in humans

    DEFF Research Database (Denmark)

    Fischer-Rasmussen, T; Krogsgaard, M R; Jensen, D B

    2002-01-01

    muscle activity in both the quadriceps and the hamstrings. The latency of the inhibition ranged between 78 and 148 ms in the quadriceps, between 88 and 110 ms in the hamstrings and between 189 and 258 ms in m. gastrocnemius. Stimulation of the fat pad of the knee did not influence the thigh and calf......We investigated the influence of electrical stimulation of the posterior cruciate ligament (PCL) on the motoneuron pool of the thigh and calf muscle during gait. The study group comprised eight young men without any history of injury to the knee joints. Multistranded teflon-insulated stainless...... over the vastus medialis, rectus femoris, vastus lateralis, biceps femoris caput longum, and semitendinosus muscles. The stimuli consisted of four pulses delivered at 200 Hz; the stimulus amplitude was two to three times the sensory threshold. The electrical stimulation of the PCL inhibited the ongoing...

  14. Investigation and clinical applications of muscle strength change in cerebrospinal fluid tap test in cases of idiopathic normal pressure hydrocephalus: A retrospective study.

    Science.gov (United States)

    Matsuoka, Tsuyoshi; Iida, Jun-Ichi; Kawahara, Makoto; Uchiyama, Yoshitomo

    2016-12-15

    The cerebrospinal fluid tap test (CSFTT) is widely used to diagnose idiopathic normal pressure hydrocephalus (iNPH) and predict the therapeutic effectiveness of shunting. However, the ability to walk cannot be quantified for patients who are unable to walk. Therefore, we examined whether the iNPH diagnostic aid is possible using dynamometry, even for patients who are unable to walk. In this study, 45 patients underwent grip strength assessment, quadriceps strength assessment, 10-m walk test, and 3-m Timed Up and Go test before and after CSFTT. Our investigation of physical functions indicated that the CSFTT-positive group demonstrated significant improvements in grip and bilateral quadriceps muscle strength. The results of the receiver operating characteristic analysis indicated that leg muscle strength measurement reliability was high and that the area under the curve was 0.754-0.811. Our investigation of the clinically effective cutoff point for the rate of change indicated that it was 13.6% for right quadriceps muscle strength and 15.3% for left quadriceps muscle strength. Comparing CSFTT results in cases of iNPH with the observed rate of change in muscle strength can aid in the diagnosis of iNPH.

  15. COMPARISON OF THE CONCENTRIC TORQUE OF KNEE MUSCLES AND TIMED-WALKING TEST IN HEALTHY AND LOW GRADE TIBIOFEMORAL OSTEOARTHRITIS

    Directory of Open Access Journals (Sweden)

    H. Bagheri

    2007-07-01

    Full Text Available The aim of study was to investigate and compare the concentric torque of Quadriceps and Hamstring muscles and Timed-Walking test in two groups. Thus, one group of healthy subjects and one group of patients with low grade of tibiofemoral osteoarthritis (OA were selected. Concentric torque of Quadriceps and Hamstring were measured in both groups. Besides, pain measurement, Timed-Walking test, range of motion and the muscle bulk of thigh were assessed in both groups. The independent t-test revealed significant differences between the two groups with regard to concentric torques and Timed-Walking test. However, no significant difference in range of motion and the muscle bulk was seen. In conclusion, patients with low grade of osteoarthritis and minimum clinical signs had weaker muscles and functional limitation in comparison with the matched healthy individuals.

  16. Assessment of muscle function using hybrid PET/MRI

    DEFF Research Database (Denmark)

    Haddock, Bryan; Holm, Søren; Poulsen, Jákup M;

    2016-01-01

    -FDG while activating the quadriceps of one leg with repeated knee extension exercises followed by hand-grip exercises for one arm. Immediately following the exercises, the subjects were scanned simultaneously with (18)F-FDG PET/MRI and muscle groups were evaluated for increases in (18)F-FDG uptake and MRI T......PURPOSE: The aim of this study was to determine the relationship between relative glucose uptake and MRI T 2 changes in skeletal muscles following resistance exercise using simultaneous PET/MRI scans. METHODS: Ten young healthy recreationally active men (age 21 - 28 years) were injected with (18)F...... 2 values. RESULTS: A significant linear correlation between (18)F-FDG uptake and changes in muscle T 2 (R (2) = 0.71) was found. for both small and large muscles and in voxel to voxel comparisons. Despite large intersubject differences in muscle recruitment, the linear correlation between (18)F...

  17. Quadriceps Strength Asymmetry After Anterior Cruciate Ligament Reconstruction Alters Knee Joint Biomechanics and Functional Performance at Time of Return to Activity.

    Science.gov (United States)

    Palmieri-Smith, Riann M; Lepley, Lindsey K

    2015-07-01

    Quadriceps strength deficits are observed clinically after anterior cruciate ligament (ACL) injury and reconstruction and are often not overcome despite rehabilitation. Given that quadriceps strength may be important for achieving symmetrical joint biomechanics and promoting long-term joint health, determining the magnitude of strength deficits that lead to altered mechanics is critical. To determine if the magnitude of quadriceps strength asymmetry alters knee and hip biomechanical symmetry as well as functional performance and self-reported function. Cross-sectional study; Level of evidence, 3. A total of 73 patients were tested at the time they were cleared for return to activity after ACL reconstruction. Quadriceps strength and activation, scores on the International Knee Documentation Committee form, the hop for distance test, and sagittal plane lower extremity biomechanics were recorded while patients completed a single-legged hop. Patients with high and moderate quadriceps strength symmetry had larger central activation ratios as well as greater limb symmetry indices on the hop for distance compared with patients with low quadriceps strength symmetry (P knee flexion angle and external moment symmetry were higher in the patients with high and moderate quadriceps symmetry compared with those with low symmetry (P knee angle and moment symmetry (P knee in the sagittal plane. Quadriceps strength was related to movement asymmetries and functional performance. Rehabilitation after ACL reconstruction needs to focus on maximizing quadriceps strength, which likely will lead to more symmetrical knee biomechanics. © 2015 The Author(s).

  18. Myoglobin plasma level related to muscle mass and fiber composition: a clinical marker of muscle wasting?

    Science.gov (United States)

    Weber, Marc-André; Kinscherf, Ralf; Krakowski-Roosen, Holger; Aulmann, Michael; Renk, Hanna; Künkele, Annette; Edler, Lutz; Kauczor, Hans-Ulrich; Hildebrandt, Wulf

    2007-08-01

    Progressive muscle wasting is a central feature of cancer-related cachexia and has been recognized as a determinant of poor prognosis and quality of life. However, until now, no easily assessable clinical marker exists that allows to predict or to track muscle wasting. The present study evaluated the potential of myoglobin (MG) plasma levels to indicate wasting of large locomotor muscles and, moreover, to reflect the loss of MG-rich fiber types, which are most relevant for daily performance. In 17 cancer-cachectic patients (weight loss 22%) and 27 age- and gender-matched healthy controls, we determined plasma levels of MG and creatine kinase (CK), maximal quadriceps muscle cross-sectional area (CSA) by magnetic resonance imaging, muscle morphology and fiber composition in biopsies from the vastus lateralis muscle, body cell mass (BCM) by impedance technique as well as maximal oxygen uptake (VO(2)max). In cachectic patients, plasma MG, muscle CSA, BCM, and VO(2)max were 30-35% below control levels. MG showed a significant positive correlation to total muscle CSA (r = 0.65, p max as an important functional readout. CK plasma levels appear to be less reliable because prolonged increases are observed in even subclinical myopathies or after exercise. Notably, cancer-related muscle wasting was not associated with increases in plasma MG or CK in this study.

  19. Association between Thigh Muscle Volume and Leg Muscle Power in Older Women.

    Directory of Open Access Journals (Sweden)

    Ulrich Lindemann

    Full Text Available The construct of sarcopenia is still discussed with regard to best appropriate measures of muscle volume and muscle function. The aim of this post-hoc analysis of a cross-sectional experimental study was to investigate and describe the hierarchy of the association between thigh muscle volume and measurements of functional performance in older women. Thigh muscle volume of 68 independently living older women (mean age 77.6 years was measured via magnetic resonance imaging. Isometric strength was assessed for leg extension in a movement laboratory in sitting position with the knee flexed at 90° and for hand grip. Maximum and habitual gait speed was measured on an electronic walk way. Leg muscle power was measured during single leg push and during sit-to-stand performance. Thigh muscle volume was associated with sit-to-stand performance power (r = 0.628, leg push power (r = 0.550, isometric quadriceps strength (r = 0.442, hand grip strength (r = 0.367, fast gait speed (r = 0.291, habitual gait speed (r = 0.256, body mass index (r = 0.411 and age (r = -0.392. Muscle power showed the highest association with thigh muscle volume in healthy older women. Sit-to-stand performance power showed an even higher association with thigh muscle volume compared to single leg push power.

  20. Association between Thigh Muscle Volume and Leg Muscle Power in Older Women.

    Science.gov (United States)

    Lindemann, Ulrich; Mohr, Christian; Machann, Juergen; Blatzonis, Konstantinos; Rapp, Kilian; Becker, Clemens

    2016-01-01

    The construct of sarcopenia is still discussed with regard to best appropriate measures of muscle volume and muscle function. The aim of this post-hoc analysis of a cross-sectional experimental study was to investigate and describe the hierarchy of the association between thigh muscle volume and measurements of functional performance in older women. Thigh muscle volume of 68 independently living older women (mean age 77.6 years) was measured via magnetic resonance imaging. Isometric strength was assessed for leg extension in a movement laboratory in sitting position with the knee flexed at 90° and for hand grip. Maximum and habitual gait speed was measured on an electronic walk way. Leg muscle power was measured during single leg push and during sit-to-stand performance. Thigh muscle volume was associated with sit-to-stand performance power (r = 0.628), leg push power (r = 0.550), isometric quadriceps strength (r = 0.442), hand grip strength (r = 0.367), fast gait speed (r = 0.291), habitual gait speed (r = 0.256), body mass index (r = 0.411) and age (r = -0.392). Muscle power showed the highest association with thigh muscle volume in healthy older women. Sit-to-stand performance power showed an even higher association with thigh muscle volume compared to single leg push power.

  1. Muscle strength and function before and after anterior cruciate ligament reconstruction using semitendonosus and gracilis.

    Science.gov (United States)

    Keays, S L; Bullock-Saxton, J; Keays, A C; Newcombe, P

    2001-10-01

    This study assessed the quadriceps and hamstring strength before and 6 months after anterior cruciate ligament (ACL) reconstructive surgery using the hamstrings and related the findings to functional performance. Six months after surgery is a critical time for assessment as this is when players are returning to sport. Maximum isokinetic strength of 31 patients with complete unilateral ACL ruptures was measured at speeds of 60 degrees and 120 degrees per second. Functional assessment included the single hop, the triple hop, the shuttle run, side-step and carioca tests. All patients underwent a controlled quadriceps emphasized home-based physiotherapy program both before and after surgery. Results show that before surgery there was a 7.3% quadriceps strength deficit at 60 degrees per second compared to the uninjured leg but no hamstring strength deficit. After surgery there was a statistically significant but relatively small loss of muscle strength. The quadriceps strength deficit had increased to 12% and there was a 10% hamstring deficit. Post-operatively there was an 11% and 6.3% improvement in the hop tests, a 9% (P < 0.01) improvement in the shuttle run, a 15% (P < 0.001) improvement in the side step and a 24% (P < 0.001) improvement in the carioca tests (P < 0.001) despite the loss of muscle strength.

  2. High-intensity resistance training amplifies muscle hypertrophy and functional gains in persons with Parkinson's disease.

    Science.gov (United States)

    Dibble, Leland E; Hale, Tessa F; Marcus, Robin L; Droge, John; Gerber, J Parry; LaStayo, Paul C

    2006-09-01

    Strength deficits in persons with Parkinson's disease (PD) have been identified as a contributor to bradykinesia. However, there is little research that examines the effect of resistance training on muscle size, muscle force production, and mobility in persons with PD. The purpose of this exploratory study was to examine, in persons with PD, the changes in quadriceps muscle volume, muscle force production, and mobility as a result of a 12-week high-force eccentric resistance training program and to compare the effects to a standard-care control. Nineteen individuals with idiopathic PD were recruited and consented to participate. Matched assignment for age and disease severity resulted in 10 participants in the eccentric group and 9 participants in the control group. All participants were tested prior to and following a 12-week intervention period with testing and training conducted at standardized times in their medication cycle. The eccentric group performed high-force quadriceps contractions on an eccentric ergometer 3 days a week for 12 weeks. The standard-care group exercise program encompassed standard exercise management of PD. The outcome variables were quadriceps muscle volume, muscle force, and mobility measures (6-minute walk, stair ascent/descent time). Each outcome variable was tested using separate one-way analyses of covariance on the difference scores. Muscle volume, muscle force, and functional status improvements occurred in persons with PD as a result of high-force eccentric resistance training. The eccentric group demonstrated significantly greater difference scores for muscle structure, stair descent, and 6-minute walk (P eccentric group consistently exceeded those in the standard-care group for all variables. To our knowledge, this is the first clinical trial to investigate and demonstrate the effects of eccentric resistance training on muscle hypertrophy, strength, and mobility in persons with PD. Additional research is needed to determine the

  3. Regional Differences in Muscle Energy Metabolism in Human Muscle by 31P-Chemical Shift Imaging.

    Science.gov (United States)

    Kime, Ryotaro; Kaneko, Yasuhisa; Hongo, Yoshinori; Ohno, Yusuke; Sakamoto, Ayumi; Katsumura, Toshihito

    2016-01-01

    Previous studies have reported significant region-dependent differences in the fiber-type composition of human skeletal muscle. It is therefore hypothesized that there is a difference between the deep and superficial parts of muscle energy metabolism during exercise. We hypothesized that the inorganic phosphate (Pi)/phosphocreatine (PCr) ratio of the superficial parts would be higher, compared with the deep parts, as the work rate increases, because the muscle fiber-type composition of the fast-type may be greater in the superficial parts compared with the deep parts. This study used two-dimensional 31Phosphorus Chemical Shift Imaging (31P-CSI) to detect differences between the deep and superficial parts of the human leg muscles during dynamic knee extension exercise. Six healthy men participated in this study (age 27±1 year, height 169.4±4.1 cm, weight 65.9±8.4 kg). The experiments were carried out with a 1.5-T superconducting magnet with a 5-in. diameter circular surface coil. The subjects performed dynamic one-legged knee extension exercise in the prone position, with the transmit-receive coil placed under the right quadriceps muscles in the magnet. The subjects pulled down an elastic rubber band attached to the ankle at a frequency of 0.25, 0.5 and 1 Hz for 320 s each. The intracellular pH (pHi) was calculated from the median chemical shift of the Pi peak relative to PCr. No significant difference in Pi/PCr was observed between the deep and the superficial parts of the quadriceps muscles at rest. The Pi/PCr of the superficial parts was not significantly increased with increasing work rate. Compared with the superficial areas, the Pi/PCr of the deep parts was significantly higher (p<0.05) at 1 Hz. The pHi showed no significant difference between the two parts. These results suggest that muscle oxidative metabolism is different between deep and superficial parts of quadriceps muscles during dynamic exercise.

  4. Use It or Lose It: Skeletal Muscle Function and Performance Results from Space Shuttle

    Science.gov (United States)

    Ryder, Jeffrey

    2011-01-01

    The Space Shuttle Program provided a wealth of valuable information regarding the adaptations of skeletal muscle to weightlessness. Studies conducted during the Extended Duration Orbiter Medical Project (EDOMP) represented ground breaking work on the effects of spaceflight on muscle form and function from applied human research to cellular adaptations. Results from detailed supplementary objective (DSO) 477 demonstrated that muscle strength losses could occur rapidly in response to short-duration spaceflight. The effects of spaceflight-induced unloading were primarily restricted to postural muscles such as those of the back as well as the knee extensors. DSO 606 provided evidence from MRI that the observed strength losses were partially accounted for by a reduction in the size of the individual muscles. Muscle biopsy studies conducted during DSO 475 were able to show muscle atrophy in individual muscle fibers from the quadriceps muscles. Reduced quadriceps muscle size and strength was also observed during the 17-d Life and Microgravity Spacelab mission aboard STS-78. Multiple maximal strength tests were conducted in flight on the calf muscles and it has been hypothesized that these high force contractions may have acted as a countermeasure. Muscle fiber mechanics were studied on calf muscle samples pre- and postflight. While some responses were crewmember specific, the general trend was that muscle fiber force production dropped and shortening velocity increased. The increased shortening velocity helped to maintain muscle fiber power. Numerous rodent studies performed during Shuttle missions suggest that many of the effects reported in Shuttle crewmembers could be due to lesions in the cellular signaling pathways that stimulate protein synthesis as well as an increase in the mechanisms that up-regulate protein breakdown. The results have important implications regarding the overall health and performance capabilities of future crewmembers that will venture beyond

  5. Muscle Disorders

    Science.gov (United States)

    Your muscles help you move and help your body work. Different types of muscles have different jobs. There are many problems that can affect muscles. Muscle disorders can cause weakness, pain or even ...

  6. Muscle Cramps

    Science.gov (United States)

    Muscle cramps are sudden, involuntary contractions or spasms in one or more of your muscles. They often occur ... minutes. It is a very common muscle problem. Muscle cramps can be caused by nerves that malfunction. Sometimes ...

  7. Relationship between muscle volume and muscle torque of the hamstrings after anterior cruciate ligament reconstruction.

    Science.gov (United States)

    Konishi, Yu; Fukubayashi, Toru

    2010-01-01

    The muscle torque per unit volume of the hamstrings on the injured and uninjured sides in patients with ACL reconstruction were compared with participants with no history of knee injury to examine whether a similar mechanism leading to quadriceps weakness exists in the hamstrings of these patients. The study population consisted of 18 and 52 patients at torque per unit volume, the peak torque of knee flexion was divided by the hamstring volume. Most muscle torque per unit volume indexes were not significantly different between the patients at torque per unit volume of patients at 12 months in both injured (0.118+/-0.03 Nm/cm(3), 60 degrees /s; 0.092+/-0.02 Nm/cm(3), 180 degrees /s) and uninjured sides (0.120+/-0.03 Nm/cm(3) at 60 degrees /s; 0.094+/-0.02 Nm/cm(3), 180 degrees /s) were significantly lower than those of controls (P<0.01). We found no evidence of recruitment disorder in the hamstrings of the patients. The results of this study indicated that the mechanism of muscle weakness of the hamstrings after reconstruction was different from that of the quadriceps, although the precise mechanism remains to be determined.

  8. Bilateral simultaneous rupture of the quadriceps tendon in a patient with psoriasis: a case report and review of the literature

    Directory of Open Access Journals (Sweden)

    Radha Sarkell

    2011-07-01

    Full Text Available Abstract Introduction Bilateral quadriceps tendon rupture is not common in the absence of systemic disease. Patients with chronic systemic diseases such as uremia and systemic lupus erythematosus and patients who are being treated with systemic steroids or local steroid injections are more prone to tendon rupture. The tendon can rupture spontaneously or as a result of trauma. We report an unusual case of simultaneous bilateral traumatic quadriceps tendon rupture in a patient with psoriasis who was being treated with topical steroid preparations. Case presentation A 57-year-old Caucasian man with a known history of psoriasis, for which he was being treated with topical steroid preparations, presented to our hospital with clinical signs of bilateral quadriceps tendon rupture after he fell while walking down stairs. The diagnosis was confirmed by bilateral ultrasound scans of the thighs. The patient underwent surgery to repair both quadriceps tendons. Post-operatively, the patient was immobilized first in bilateral cylinder casts for six weeks, then in knee braces for the next four weeks. His knees were actively mobilized during physiotherapy. Conclusion Bilateral quadriceps tendon rupture is a rare occurrence in patients with psoriasis who are being treated with topical steroids.

  9. Muscle Activation Differs between Three Different Knee Joint-Angle Positions during a Maximal Isometric Back Squat Exercise

    Directory of Open Access Journals (Sweden)

    Paulo Henrique Marchetti

    2016-01-01

    Full Text Available The purpose of this study was to compare muscle activation of the lower limb muscles when performing a maximal isometric back squat exercise over three different positions. Fifteen young, healthy, resistance-trained men performed an isometric back squat at three knee joint angles (20°, 90°, and 140° in a randomized, counterbalanced fashion. Surface electromyography was used to measure muscle activation of the vastus lateralis (VL, vastus medialis (VM, rectus femoris (RF, biceps femoris (BF, semitendinosus (ST, and gluteus maximus (GM. In general, muscle activity was the highest at 90° for the three quadriceps muscles, yet differences in muscle activation between knee angles were muscle specific. Activity of the GM was significantly greater at 20° and 90° compared to 140°. The BF and ST displayed similar activation at all joint angles. In conclusion, knee position alters muscles activation of the quadriceps and gluteus maximus muscles. An isometric back squat at 90° generates the highest overall muscle activation, yet an isometric back squat at 140° generates the lowest overall muscle activation of the VL and GM only.

  10. Chronic AMP-activated protein kinase activation and a high-fat diet have an additive effect on mitochondria in rat skeletal muscle.

    Science.gov (United States)

    Fillmore, Natasha; Jacobs, Daniel L; Mills, David B; Winder, William W; Hancock, Chad R

    2010-08-01

    Factors that stimulate mitochondrial biogenesis in skeletal muscle include AMP-activated protein kinase (AMPK), calcium, and circulating free fatty acids (FFAs). Chronic treatment with either 5-aminoimidazole-4-carboxamide riboside (AICAR), a chemical activator of AMPK, or increasing circulating FFAs with a high-fat diet increases mitochondria in rat skeletal muscle. The purpose of this study was to determine whether the combination of chronic chemical activation of AMPK and high-fat feeding would have an additive effect on skeletal muscle mitochondria levels. We treated Wistar male rats with a high-fat diet (HF), AICAR injections (AICAR), or a high-fat diet and AICAR injections (HF + AICAR) for 6 wk. At the end of the treatment period, markers of mitochondrial content were examined in white quadriceps, red quadriceps, and soleus muscles, predominantly composed of unique muscle-fiber types. In white quadriceps, there was a cumulative effect of treatments on long-chain acyl-CoA dehydrogenase, cytochrome c, and peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) protein, as well as on citrate synthase and beta-hydroxyacyl-CoA dehydrogenase (beta-HAD) activity. In contrast, no additive effect was noted in the soleus, and in the red quadriceps only beta-HAD activity increased additively. The additive increase of mitochondrial markers observed in the white quadriceps may be explained by a combined effect of two separate mechanisms: high-fat diet-induced posttranscriptional increase in PGC-1alpha protein and AMPK-mediated increase in PGC-1alpha protein via a transcriptional mechanism. These data show that chronic chemical activation of AMPK and a high-fat diet have a muscle type specific additive effect on markers of fatty acid oxidation, the citric acid cycle, the electron transport chain, and transcriptional regulation.

  11. Hamstrings to quadriceps peak torque ratios diverge between sexes with increasing isokinetic angular velocity.

    Science.gov (United States)

    Hewett, Timothy E; Myer, Gregory D; Zazulak, Bohdanna T

    2008-09-01

    Our purpose was to determine if females demonstrate decreased hamstrings to quadriceps peak torque (H/Q) ratios compared to males and if H/Q ratios increase with increased isokinetic velocity in both sexes. Maturation disproportionately increases hamstrings peak torque at high velocity in males, but not females. Therefore, we hypothesised that mature females would demonstrate decreased H/Q ratios compared to males and the difference in H/Q ratio between sexes would increase as isokinetic velocity increased. Studies that analysed the H/Q ratio with gravity corrected isokinetic strength testing reported between 1967 and 2004 were included in our review and analysis. Keywords were hamstrings/quadriceps, isokinetics, peak torque and gravity corrected. Medline and Smart databases were searched combined with cross-checked bibliographic reference lists of the publications to determine studies to be included. Twenty-two studies were included with a total of 1568 subjects (1145 male, 423 female). Males demonstrated a significant correlation between H/Q ratio and isokinetic velocity (R=0.634, pratio at the lowest angular velocity (47.8+/-2.2% at 30 degrees /s) compared to the highest velocity (81.4+/-1.1% at 360 degrees /s, pratio and isokinetic velocity (R=0.065, p=0.77) or a change in relative hamstrings strength as the speed increased (49.5+/-8.8% at 30 degrees /s; 51.0+/-5.7% at 360 degrees /s, p=0.84). Gender differences in isokinetic H/Q ratios were not observed at slower angular velocities. However, at high knee flexion/extension angular velocities, approaching those that occur during sports activities, significant gender differences were observed in the H/Q ratio. Females, unlike males, do not increase hamstrings to quadriceps torque ratios at velocities that approach those of functional activities.

  12. Evaluation of healthy muscle tissue by strain and shear wave elastography – Dependency on depth and ROI position in relation to underlying bone

    DEFF Research Database (Denmark)

    Ewertsen, Caroline; Carlsen, Jonathan Frederik; Christiansen, Iben Riishede

    2016-01-01

    and methods: Ten healthy volunteers (five males and five females) had their biceps brachii, gastrocnemius, and quadriceps muscle examined with strain- and shear wave elastography at three different depths and in regions located above bone and beside bone. Strain ratios were averaged from cine-loops of 10 s...

  13. Effect of formoterol, a long-acting β2-adrenergic agonist, on muscle strength and power output, metabolism and fatigue during maximal sprinting in men

    DEFF Research Database (Denmark)

    Kalsen, Anders; Hostrup, Morten; Backer, Vibeke

    2016-01-01

    L min(-1) kg(-1)) performed a 30-s cycle ergometer sprint after inhalation of either 54 µg formoterol (FOR) or placebo (PLA). Before and after the sprint, muscle biopsies were collected from vastus lateralis and maximal voluntary contraction (MVC) and contractile properties of quadriceps were measured...

  14. Muscle hypertrophy in quadriplegics with combined electrical stimulation and body weight support training.

    Science.gov (United States)

    Carvalho de Abreu, Daniela Cristina; Júnior, Alberto Cliquet; Rondina, Jane Maryan; Cendes, Fernando

    2008-06-01

    We describe the analysis of muscle hypertrophy in complete quadriplegics after 6 months of treadmill gait training with neuromuscular electrical stimulation (NMES). We aim to evaluate the effect of treadmill gait training using NMES, with 30-50% body weight relief, on muscle mass. Fifteen quadriplegics were divided into gait (n=8) and control (n=7) groups. The gait group (GG) performed training, associated to partial body weight support, for 6 months, twice a week, for 20 min. Control group (CG) individuals performed only conventional physiotherapy, but did not perform gait training using NMES. Magnetic resonance imaging (MRI) was performed over quadriceps, at the beginning and after 6 months. The MRI was done to determine the average of cross-sectional area of the quadriceps. Moreover, a gray scale was used to separate the muscle from the conjunctive tissue (when the value is closer to 225, there is a higher amount of muscle tissue). After 6 months there was an increase of cross-sectional area in the gait group (from 49.81+/-9.36 to 57.33+/-10.32 cm2; P=0.01), but not in the control group (from 43.60+/-7.56 to 41.65 +/- 9.44 cm2; P=0.17). The gray scale did not show significant differences after 6 months; however, the mean value of the gray scale inside the quadriceps in the gait group increased by 7.7% and in the control group decreased by 11.4%. Treadmill gait associated with NMES was efficient to promove quadriceps muscle hypertrophy in quadriplegics with chronic lesions even when a partial body weight support was provided.

  15. Neuromuscular versus quadriceps strengthening exercise in patients with medial knee osteoarthritis and varus malalignment

    DEFF Research Database (Denmark)

    Bennell, Kim L; Kyriakides, Mary; Metcalf, Ben

    2014-01-01

    OBJECTIVE: To compare the effects of neuromuscular exercise (NEXA) and quadriceps strengthening (QS) on the knee adduction moment (an indicator of mediolateral distribution of knee load), pain, and physical function in patients with medial knee joint osteoarthritis (OA) and varus malalignment...... component. Primary outcomes were peak external knee adduction moment (3-dimensional gait analysis), pain (visual analog scale), and self-reported physical function (Western Ontario and McMaster Universities Osteoarthritis Index). RESULTS: Eighty-two patients (38 [76%] of 50 in the NEXA group and 44 [88...

  16. Long-term quadriceps femoris functional deficits following intramedullary nailing of isolated tibial fractures

    OpenAIRE

    Nyland, J.; Bealle, D.P.; Kaufer, H.; Johnson, D L

    2000-01-01

    This retrospective study assessed 5 male and 5 female patients, age 35.1±16 years, height 171.8±12 cm, and weight 75.5±18 kg (mean±SD) who were more than 1 year post isolated tibial fracture (18±6 months) and had been treated with an intramedullary tibial nail. Subjects completed a 12-question visual analog scale, a physical symptom and activity of daily living survey, and were also tested for bilateral isokinetic (60°/s) quadriceps femoris and hamstring strength. Knee pain during activity, s...

  17. Simultaneous traumatic rupture of the patellar tendon and the contralateral quadriceps tendon in a healthy individual.

    Science.gov (United States)

    Kumar, S; Rachakatla, N; Kerin, C; Kumar, R

    2010-11-05

    A simultaneous traumatic complete rupture of the patellar tendon and the contralateral quadriceps tendon is reported to occur in patients with renal failure and other inflammatory diseases, but is extremely rare in a healthy individual because of the different contributory factors and mechanisms of injury. We present a rare case report of such a combination of injuries in a 48-year-old healthy man. To our knowledge only three such cases have been reported in the English literature. This is an unusual combination and hence there is potential for missed diagnosis leading to suboptimal treatment.

  18. Assessment of isokinetic muscle function in Korea male volleyball athletes

    Science.gov (United States)

    Kim, Chang-Gyun; Jeoung, Bog Ja

    2016-01-01

    Volleyball players performed numerous repetitions of spike actions, which uses and requires strong and explosive force, and control of the muscles of the shoulder, lower back, and legs. Muscle imbalance is one of the main causes of sport injuries. The purpose of this study was to assess isokinetic muscle functions in male volleyball players. We thus aim to accurately evaluate their muscle functions, and identify the best training strategy to achieve optimal muscle strength balance in future training programs. The participants in this study consisted of 14 male volleyball players. Muscle strength was measured using the isokinetic dynamometer. Muscle strength was evaluated in terms of peak torque and average power, calculated from five repeated measurements at an angular speed of 60°/sec. Three players who were left attackers showed shoulder imbalance, four players showed trunk joint imbalance, nine players had knee joint of extension/flexion imbalance and four players showed left/right imbalance. The results showed that the number of volleyball players with differences between the strength of the bilateral knee muscles, and between the strength of the hamstrings and quadriceps muscles was higher than the number of players with differences between the strength of the shoulder internal and external rotation muscles, and higher than the number of players with differences between the strength of the lower back extension and flexion muscles. PMID:27807521

  19. Gait Variability Related to Muscle Quality and Muscle Power Output in Frail Nonagenarian Older Adults.

    Science.gov (United States)

    Martinikorena, Ion; Martínez-Ramírez, Alicia; Gómez, Marisol; Lecumberri, Pablo; Casas-Herrero, Alvaro; Cadore, Eduardo L; Millor, Nora; Zambom-Ferraresi, Fabricio; Idoate, Fernando; Izquierdo, Mikel

    2016-02-01

    Frailty has become the center of attention of basic, clinical, and demographic research because of its incidence level and the gravity of adverse outcomes with age. Moreover, with advanced age, motor variability increases, particularly in gait. Muscle quality and muscle power seem to be closely associated with performance on functional tests in frail populations. Insight into the relationships among muscle power, muscle quality, and functional capacity could improve the quality of life in this population. In this study, the relationship between the quality of the muscle mass and muscle strength with gait performance in a frail population was examined. Twenty-two institutionalized frail elderly individuals (93.1 ± 3.6) participated in this study. Muscle quality was measured by segmenting areas of high- and low-density fibers as observed in computed tomography images. The assessed functional outcomes were leg strength and power, velocity of gait, and kinematic gait parameters obtained from a tri-axial inertial sensor. Our results showed that a greater number of high-density fibers, specifically those of the quadriceps femoris muscle, were associated with better gait performance in terms of step time variability, regularity, and symmetry. Additionally, gait variability was associated with muscle power. In contrast, no significant relationship was observed between gait velocity and either muscle quality or muscle power. Gait pattern disorders could be explained by a deterioration of the lower limb muscles. It is known that an impaired gait is an important predictor of falls in older populations; thus, the loss of muscle quality and power could underlie the impairments in motor control and balance that lead to falls and adverse outcomes. Copyright © 2016 AMDA – The Society for Post-Acute and Long-Term Care Medicine. Published by Elsevier Inc. All rights reserved.

  20. Real-time noninvasive optical imaging of exercising muscle and brain upon cognitive stimuli

    Science.gov (United States)

    Quaresima, Valentina; van der Sluijs, Marco C.; Menssen, Jan; Grillotti, Lucia; Ferrari, Marco; Colier, Willy N.

    2001-06-01

    The monitoring of a single muscle location does not reflect the heterogeneity of the muscle groups activation during exercise. In the past, measurements of oxygen consumption (VO2) at single muscle locations could be carried out non-invasively by near-infrared continuous wave spectroscopy (NIRCWS) at rest or during isometric contractions. In the present study, human regional quadriceps (vastus lateralis and rectus femoris) VO2 was investigated at rest and during maximal voluntary contractions using a 12- channel NIRCWS system with an acquisition time of 0.1 s.

  1. [Skeletal muscle mixed fiber tissue metabolism in rats after a flight on the Kosmos-690 biosatellite].

    Science.gov (United States)

    Gaevskaia, M S; Belitskaia, R A; Kolganova, N S; Kolchina, E V; Kurkina, L M

    1979-01-01

    On the R+O day the quadriceps muscle of rats showed a decrease in the content of T protein and an inhibition of LDH activity of sacroplasmatic proteins. These changes resulted from the combined affect of space flight factors and gamma-irradiation, and may be considered as a decline of compensatory synthetic processes responsible for the recovery of muscle proteins in weightlessness. Inhibition of the age-associated shift of the M:H ratio of LDH found on the R+25 day can be attributed to the inhibitory effect of gamma-irradiation. No change in the content of glycogen in the gastrocnemius muscle of flight rats was noted.

  2. Light-load resistance exercise increases muscle protein synthesis and hypertrophy signaling in elderly men

    DEFF Research Database (Denmark)

    Agergaard, Jakob; Bülow, Jacob; Jensen, Jacob K

    2017-01-01

    INTRODUCTION: The present study investigated whether well-tolerated light-load resistance exercise (LL-RE) affects skeletal muscle fractional synthetic rate (FSR) and anabolic intracellular signaling as a way to counteract age-related loss of muscle mass. METHODS: Untrained healthy men (age: +65...... and 12g whey protein at 7 hours post-exercise; N=10) or placebo (4g maltodextrin/hour; N=10). Quadriceps muscle biopsies were taken at 0, 3, 7 and 10 hours post-exercise from both the resting and exercised leg. Myofibrillar-FSR and activity of select targets from the mTORC1-signalling cascade were...

  3. Peak muscle perfusion and oxygen uptake in humans: importance of precise estimates of muscle mass.

    Science.gov (United States)

    Râdegran, G; Blomstrand, E; Saltin, B

    1999-12-01

    The knee extensor exercise model was specifically developed to enable in vivo estimates of peak muscle blood flow and O(2) uptake in humans. The original finding, using thermodilution measurements to measure blood flow in relation to muscle mass [P. Andersen and B. Saltin. J. Physiol. (Lond.) 366: 233-249, 1985], was questioned, however, as the measurements were two- to threefold higher than those previously obtained with the (133)Xe clearance and the plethysmography technique. As thermodilution measurements have now been confirmed by other methods and independent research groups, we aimed to address the impact of muscle mass estimates on the peak values of muscle perfusion and O(2) uptake. In the present study, knee extensor volume was determined from multiple measurements with computer tomography along the full length of the muscle. In nine healthy humans, quadriceps muscle volume was 2.36 +/- 0.17 (range 1. 31-3.27) liters, corresponding to 2.48 +/- 0.18 (range 1.37-3.43) kg. Anthropometry overestimated the muscle volume by approximately 21-46%, depending on whether quadriceps muscle length was estimated from the patella to either the pubic bone, inguinal ligament, or spina iliaca anterior superior. One-legged, dynamic knee extensor exercise up to peak effort of 67 +/- 7 (range 55-100) W rendered peak values for leg blood flow (thermodilution) of 5.99 +/- 0.66 (range 4.15-9.52) l/min and leg O(2) uptake of 856 +/- 109 (range 590-1,521) ml/min. Muscle perfusion and O(2) uptake reached peak values of 246 +/- 24 (range 149-373) and 35.2 +/- 3.7 (range 22.6-59. 6) ml. min(-1). 100 g muscle(-1), respectively. These peak values are approximately 19-33% larger than those attained by applying anthropometric muscle mass estimates. In conclusion, the present findings emphasize that peak perfusion and O(2) uptake in human skeletal muscle may be up to approximately 30% higher than previous anthropometric-based estimates that use equivalent techniques for blood flow

  4. EFFECTS OF KINESIOTAPING ALONG WITH QUADRICEPS STRENGTHENING EXERCISES ON PAIN, JOINT RANGE OF MOTION AND FUNCTIONAL ACTIVITIES OF KNEE IN SUBJECTS WITH PATELLOFEMORAL OSTEOARTHRITIS

    Directory of Open Access Journals (Sweden)

    M. Harshitha

    2014-08-01

    Full Text Available Background: Patello femoral Osteoarthritis is the most common degenerative disease in older age group, causing pain, physical disability, and decreased quality of life.As many treatment options available, kinesiotaping is an efficacious treatment for management of pain & disability in patellofemoral joint osteoarthritis. Previous studies have shown that kinesiotaping as well as quadriceps strengthening significantly yields functional benefits. But there is lack of evidence revealing combined effectiveness & effects of kinesiotaping along with quadriceps strengthening in subjects with patellofemoral joint osteoarthritis. Methods: 30 subjects with symptoms of patellofemoral osteoarthritis fulfilled the inclusion criteria were randomly assigned into 2 groups of 15 in each group. Taping along with quadriceps strengthening program is compared to the quadriceps strengthening program alone. Pain were measured by Visual Analogue Scale (VAS, knee ROM were measured by Goniometer, Functional status were measured by Western Ontario McMaster Universities index (WOMAC, score. Measurements were taken pre & post intervention. Results: The results indicated that kinesiotaping along with quadriceps strengthening exercises showed there was statistically significant improvement in pain (<0.05, knee ROM (<0.05 and functional activities (<0.05 after 6 weeks compared to quadriceps strengthening alone. Conclusion: Subjects with kinesiotaping along with quadriceps strengthening showed significant improvement in reducing pain, in improving ROM & functional activities at the end of 6th week treatment when compared to subjects with patellofemoral osteoarthritis underwent quadriceps strengthening exercises alone.

  5. Recovery of atrophic leg muscles in the hemiplegics due to cerebrovascular accidents. Computed tomographic study

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    Odajima, Natsu; Ishiai, Sumio; Okiyama, Ryouichi; Furukawa, Tetsuo; Tsukagoshi, Hiroshi.

    1988-02-01

    Thirty-five patients with hemiplegia due to cerebrovascular accidents were studied with regared to the muscle wastings before and after rehabilitation training. Hemiplegics were composed of 12 improved and 23 non-improved patients. The CT scan was carried out at the midportion of the thigh and largest-diameter section of the calf. Muscle size of each cross-sectional area was measured on CT image and the increase of size (..delta..S) in each muscle after training was calculated. The ..delta..S of quadriceps femoris was correlated with that of whole cross-section of the thigh. The gracilis in non-affected side was not correlated with that of whole muscles. In both legs, there was an increase in leg muscle size after training. These changes were nost marked in the non-affected side of the improved patients. After training the difference between the two limbs remained unchanged. Recovery of muscle wasting in both legs was seen first in the quadriceps in thigh and flexors in calf. Gracilis was relatively unchanged in comparison with other muscles. Remarkable increase of muscle size in non-affected side was worthwhile to note.

  6. Effect of 3 Different Applications of Kinesio Taping Denko® on Electromyographic Activity: Inhibition or Facilitation of the Quadriceps of Males During Squat Exercise

    Science.gov (United States)

    Serrão, Júlio C.; Mezêncio, Bruno; Claudino, João G.; Soncin, Rafael; Miyashiro, Pedro L. Sampaio; Sousa, Eric P.; Borges, Eduardo; Zanetti, Vinícius; Phillip, Igor; Mochizuki, Luiz; Amadio, Alberto C.

    2016-01-01

    Kinesio taping consists of a technique which uses the application of an elastic adhesive tape. It has become a widely used rehabilitation modality for the prevention and treatment of musculoskeletal disorders. The objective of this study was to verify the effect of the application of Kinesio Taping Denko® in three conditions (facilitation, inhibition, and placebo) on the electromyographic activity of the quadriceps and hamstrings muscles on facilitating or inhibiting the muscle function and on the perceived exertion during the barbell back squat exercise in healthy male subjects. Methods: It was a randomized, single-blinded and controlled study in which 18 males (28.0 ± 6.7 years old; 85.8 ± 8.2 kg mass; 1.80 ± 0.07 m tall; 0.97 ± 0.04 m lower limb length) performed barbell back squat exercise with different conditions of Kinesio Taping Denko® applications: Facilitation, inhibition and placebo. Previous to the mentioned conditions, all individuals were assessed without applying kinesio Taping Denko® during the exercise. OMNI scale was used after each set for perceived exertion evaluation. No differences (p electromyography activity of vastus lateralis, vastus medialis, and biceps femoris during the squat exercise. Furthermore, the perceived exertion was not affected by the kinesio taping denko® application. Key points Researchers involved in collecting data in this study have no financial or personal interest in the outcome of results or the sponsor. The perceived exertion was not affected by the kinesiology taping application. Kinesiology taping application may not alter the magnitude of EMG activity of vastuslateralis, vastusmedialis, and biceps femoris during the barbell back squat exercise. Electromyographic activity of kinesiology taping application on other muscle groups and in other cohorts, such as healthy elderly subjects and patients under a rehabilitation program require further investigation.

  7. Simultaneous rupture of the quadriceps tendon and contralateral patellar tendon in a patient with chronic renal failure.

    Science.gov (United States)

    Muratli, Hasan Hilmi; Celebi, Levent; Hapa, Onur; Biçimoğlu, Ali

    2005-01-01

    Simultaneous quadriceps and patellar tendon rupture is rare. Mechanical factors and coexisting systemic and local factors are taken into consideration in the pathogenesis of these ruptures. In patients with some chronic systemic diseases, simultaneous rupture can occur spontaneously or with minor traumas. We present a case of simultaneous quadriceps and patellar tendon rupture in a 21-year-old man with chronic renal failure in this report. He was treated surgically by osseotendinous repair with suture anchors and supplemental cerclage wire fixation on both sides. He regained his normal knee joint functions 18 months after the operation.

  8. Horizontal intra-articular patellar dislocation resulting in quadriceps avulsion and medial patellofemoral ligament tear: a case report.

    Science.gov (United States)

    Kramer, Dennis E; Simoni, Michael K

    2013-07-01

    Intra-articular patellar dislocations are rare. We present a 13-year-old boy who sustained a complete horizontal intra-articular patellar dislocation following blunt trauma to the flexed knee. Closed reduction was unsuccessful and open reduction indicated a repairable quadriceps avulsion and medial patellofemoral ligament tear. He is the youngest patient to sustain a quadriceps rupture and the only patient to sustain a medial patellofemoral ligament tear to date. His flexed knee and the horizontally positioned patella (seen on lateral radiograph) were indicative of a complete rotational injury with extensor mechanism involvement. Open reduction allowed for the repair of both injuries and a favorable outcome.

  9. Floating patella: combined quadriceps tendon, retinacula, and patellar tendon ruptures in a high-performance elite athlete.

    Science.gov (United States)

    Langer, Phillip R; Selesnick, F Harlan

    2010-09-01

    Simultaneous quadriceps and patellar tendon rupture is rare. To our knowledge, we present the first known case of simultaneous quadriceps tendon, patella tendon, and retinacula rupture in the ipsilateral knee of a high-performance elite athlete. This disabling injury in the active person results in an inability to actively obtain and maintain full knee extension. When the tendons do not heal properly, at the correct length and tension, knee range of motion and strength can become significantly altered, leading to early fatigue, patellofemoral pain, and possibly instability, preventing return to preinjury status. Immediate surgical repair is recommended for optimal return of knee function and power.

  10. Predicting muscle forces of individuals with hemiparesis following stroke

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    Maladen Ryan

    2008-02-01

    Full Text Available Abstract Background Functional electrical stimulation (FES has been used to improve function in individuals with hemiparesis following stroke. An ideal functional electrical stimulation (FES system needs an accurate mathematical model capable of designing subject and task-specific stimulation patterns. Such a model was previously developed in our laboratory and shown to predict the isometric forces produced by the quadriceps femoris muscles of able-bodied individuals and individuals with spinal cord injury in response to a wide range of clinically relevant stimulation frequencies and patterns. The aim of this study was to test our isometric muscle force model on the quadriceps femoris, ankle dorsiflexor, and ankle plantar-flexor muscles of individuals with post-stroke hemiparesis. Methods Subjects were seated on a force dynamometer and isometric forces were measured in response to a range of stimulation frequencies (10 to 80-Hz and 3 different patterns. Subject-specific model parameter values were obtained by fitting the measured force responses from 2 stimulation trains. The model parameters thus obtained were then used to obtain predicted forces for a range of frequencies and patterns. Predicted and measured forces were compared using intra-class correlation coefficients, r2 values, and model error relative to the physiological error (variability of measured forces. Results Results showed excellent agreement between measured and predicted force-time responses (r2 >0.80, peak forces (ICCs>0.84, and force-time integrals (ICCs>0.82 for the quadriceps, dorsiflexor, and plantar-fexor muscles. The model error was within or below the +95% confidence interval of the physiological error for >88% comparisons between measured and predicted forces. Conclusion Our results show that the model has potential to be incorporated as a feed-forward controller for predicting subject-specific stimulation patterns during FES.

  11. A Rare Case of Simultaneous Acute Bilateral Quadriceps Tendon Rupture and Unilateral Achilles Tendon Rupture

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    Wei Yee Leong

    2013-07-01

    Full Text Available Introduction: There have been multiple reported cases of bilateral quadriceps tendon ruptures (QTR in the literature. These injuries frequently associated with delayed diagnosis, which results in delayed surgical treatment. In very unusual cases, bilateral QTRs can be associated with other simultaneous tendon ruptures. Case Report: We present a rare case of bilateral QTR with a simultaneous Achilles Tendon Rupture involving a 31 years old Caucasian man who is a semi-professional body builder taking anabolic steroids. To date bilateral QTR with additional TA rupture has only been reported once in the literature and to our knowledge this is the first reported case of bilateral QTR and simultaneous TA rupture in a young, fit and healthy individual. Conclusion: The diagnosis of bilateral QTR alone can sometimes be challenging and the possibility of even further tendon injuries should be carefully assessed. A delay in diagnosis could result in delay in treatment and potentially worse outcome for the patient. Keywords: Quadriceps tendon rupture; Achilles tendon rupture; Bilateral.

  12. Bilateral quadriceps rupture: results with and without platelet-rich plasma.

    Science.gov (United States)

    Lanzetti, Riccardo Maria; Vadalà, Antonio; Morelli, Federico; Iorio, Raffaele; Ciompi, Alessandro; Vetrano, Mario; Argento, Giuseppe; Vulpiani, Maria Chiara; Di Sanzo, Vincenzo; Ferretti, Andrea

    2013-11-01

    This article presents a 46-year-old man with bilateral atraumatic quadriceps rupture that occurred while he was descending stairs. The patient underwent surgery the day after the accident. In the left knee, quadriceps reinsertion was performed using a conventional technique. In the right knee, platelet-rich plasma (PRP), both in its liquid and semisolid patterns, was added intraoperatively. Ultrasonography and magnetic resonance imaging evaluations were performed 1, 6, and 24 months postoperatively. At 6 and 24 months postoperatively, clinical and functional evaluations also were performed. Clinical examination showed no differences between the knees, and functional scores were the same for both knees. Ultrasonographic evaluation showed bilateral persistent tendon thickening and gross echotexture abnormalities, with no side-to-side differences. Magnetic resonance imaging showed signals of vascularized granulation tissue in both knees, which was more evident in the right (PRP) knee at 1 month postoperatively, along with a better signal of scar tissue in the right knee at 6 and 24 months postoperatively. The use of PRP yielded no better clinical or functional results than the lack of its use. However, a more intense and significant reparative healing process occurred where the PRP was used, thus suggesting a more rapid completion of the healing process, although this effect seems to remain only a radiographic finding with no clinical correlation.

  13. Simultaneous reconstruction of quadriceps tendon rupture after TKA and neglected Achilles tendon rupture.

    Science.gov (United States)

    Lee, Yong Seuk; Min, Byoung-Hyun; Han, Kyeong-Jin; Cho, Jae Ho; Han, Seung Hwan; Lee, Doo-Hyung; Oh, Kyung Soo

    2010-05-12

    We report a case of simultaneous reconstruction of a quadriceps tendon rupture after total knee arthroplasty (TKA) and neglected Achilles tendon rupture, which occurred before TKA with an ipsilateral hamstring autograft. A 64-year-old woman presented with persistent right knee pain. She also had right heel pain and had received multiple steroid injections at the knee joint and heel. On examination, she showed osteoarthritis in the medial and lateral compartments of the knee joint and an Achilles tendon rupture in the ipsilateral limb. There was skin dimpling and the proximal portion of tendon was migrated. We performed TKA, and the postoperative course was satisfactory. She returned 3 months postoperatively, however, with skin dimpling around the suprapatellar area and weakness of knee extension. Her ankle symptoms were also aggravated because she could not use the knee joint freely. We performed simultaneous reconstruction of the quadriceps tendon and the Achilles tendon using an ipsilateral hamstring autograft.Hamstring autograft offers a good alternative treatment option for rupture repair, particularly with concommitant ruptures of multiple sites when primary repair is not possible or the viability of repaired tissue is poor.

  14. Sequential rupture of triceps and quadriceps tendons in a dialysis patient using hormone supplements.

    Science.gov (United States)

    Soo, I; Christiansen, J; Marion, D; Courtney, M; Luyckx, V A

    2011-02-01

    Spontaneous rupture of tendons is rare, and typically occurs in large weight bearing tendons such as the quadriceps, Achilles and patellar tendon, in the context of various chronic diseases including end-stage renal disease. In general, tendon rupture in dialysis patients is associated with hyperparathyroidism, long duration of dialysis, steroid and quinolone use. We present a case of a young man on chronic dialysis who presented with sequential rupture of triceps and quadriceps tendons requiring surgical repair, several months after initiating use of multiple hormone supplements including human growth hormone and androgens. The supplements were obtained over the internet with the aim of improving his kidney function. Although this patient did have hyperparathyroidism, it is likely his PTH elevation was exacerbated by use of human growth hormone, and tendon rupture risk increased by concurrent use of an androgen supplement. This case highlights the fact that dialysis patients do utilize alternative remedies and that there may be unexpected, dialysis-specific complications associated with their use.

  15. Antagonist muscle moment is increased in ACL deficient subjects during maximal dynamic knee extension

    DEFF Research Database (Denmark)

    Alkjær, Tine; Simonsen, Erik B; Magnusson, S Peter

    2012-01-01

    INTRODUCTION: Coactivation of the hamstring muscles during dynamic knee extension may compensate for increased knee joint laxity in anterior cruciate ligament (ACL) deficient subjects. This study examined if antagonist muscle coactivation during maximal dynamic knee extension was elevated...... in subjects with anterior cruciate ligament (ACL) deficiency compared to age-matched healthy controls. METHODS: Electromyography (EMG) and net knee joint moments were recorded during maximal concentric quadriceps and eccentric hamstring contractions, performed in an isokinetic dynamometer (ROM: 90......-10°, angular speed: 30°/s). Hamstring antagonist EMG recorded during concentric quadriceps contraction was converted into antagonist moment based on the EMG-moment relationship observed during eccentric agonist contractions. RESULTS: The magnitude of antagonist hamstring EMG was 65.5% higher in ACL deficient...

  16. Changes in skeletal muscle after discontinuation of growth hormone treatment in young adults with hypopituitarism.

    Science.gov (United States)

    Rutherford, O M; Jones, D A; Round, J M; Preece, M A

    1989-01-01

    Skeletal muscle strength and size were measured for 1 year following discontinuation of human growth hormone (hGH) treatment in 11 patients with hypopituitarism. Quadriceps and forearm flexor maximum voluntary isometric strength and size were measured. At the end of the study, endocrine status was reassessed by an insulin tolerance test. Three of the 11 subjects were found to have normal hGH secretion and were not included in the analysis. At 12 months, quadriceps strength, size and fibre areas were 94.0 +/- 8.5%, 94.5 +/- 6.3% and 85.6 +/- 17.7% (mean +/- SD), respectively, of baseline values. Forearm flexor strength and size were 101.4 +/- 7.9% and 92 +/- 9.2% of control values. Although these changes are relatively small, they suggest a role for growth hormone in the maintenance of muscle in the adult.

  17. EFFECTS OF MESSAGE VS ACTIVE EXERCISES ON EXPERIMENTALLY INDUCED DELAYED ONSET OF MUSCLE SORENESS

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    A. Chaturvedi Pilladi *,

    2013-12-01

    Full Text Available Background:To evaluate the effect of massage of versus active exercises on experimentally induced delayedonset of muscle soreness.Method:30 subjects were divided into two groups, Experimental group received Massage and control groupreceived active exercises, results were taken by measurement of pain and functional stair climbing capacity ofknee joint were taken by visual analog score and functional knee rating score.Results:obtained results were analyzed with the use of Paired T-test, which has been carried out to observethetreatment impact between the groups before and after the treatment. After a 4 week treatment period,thesubjects in the Group I (Quadriceps message compared with the subjects in the Group II (Active exercise hadshown a statistically significant improvement with the outcome measures at 0.05 level.Conclusion:Quadriceps massagewas found much effective in decreasing Delayed onset of muscle sorenessthan active exercises.

  18. Acute botulinum toxin-induced muscle weakness in the anterior cruciate ligament-deficient rabbit.

    Science.gov (United States)

    Longino, David; Frank, Cy; Herzog, Walter

    2005-11-01

    We established botulinum type-A toxin (BTX-A) injections as a powerful tool to cause knee extensor weakness in New Zealand White (NZW) rabbits. The purpose of this study was to determine if BTX-A induced quadriceps weakness causes muscle dysfunction beyond that caused by anterior cruciate ligament (ACL) transection in the knee of NZW rabbits. Twenty animals were randomly divided into four study groups (n=5 each); uninjected controls, BTX-A injection alone, ACL transection alone, BTX-A injection and ACL transection combined. Isometric knee extensor torque, quadriceps muscle mass, and vertical and anterior-posterior ground reaction forces were measured four weeks post single (BTX-A and ACL), unilateral intervention. Muscle weakness, muscle atrophy and decrease in ground reaction forces were all significantly greater for the experimental compared to the untreated contralateral legs. BTX-A injection produced a greater deficit in quadriceps mass and knee extensor torque than ACL transection alone, but produced smaller deficits in the ground reaction forces. ACL transection superimposed on BTX-A injection did not change either knee extensor torque production or muscle mass. Together these results suggest that BTX-A injection causes great force and muscle mass deficits, and affects functional gait in a significant manner, but it has no measurable functional effect when superimposed on ACL transection, at least not in the acute protocol tested here. Hopefully, BTX-A injection for acutely enhancing the degree of muscle weakness in otherwise untreated animals, or in experimental models of osteoarthritis, will help in investigating the role of muscle weakness in joint degeneration.

  19. Knee proprioception after exercise-induced muscle damage.

    Science.gov (United States)

    Torres, R; Vasques, J; Duarte, J A; Cabri, J M H

    2010-06-01

    The purpose of the present study was to investigate whether exercise-induced quadriceps muscle damage affects knee proprioception such as joint position sense (JPS), force sense and the threshold to detect passive movement (TTDPM). Fourteen young men performed sets of eccentric quadriceps contractions at a target of 60% of the maximal concentric peak torque until exhaustion; the exercise was interrupted whenever the subject could not complete two sets. Muscle soreness, JPS, the TTDPM and force sense were examined before the exercise as well as one, 24, 48, 72 and 96 h after exercise. The results were compared using one-way repeated-measure ANOVA. Plasma CK activity, collected at the same times, was analyzed by the Friedman's test to discriminate differences between baseline values and each of the other assessment moments (pknee flexion and force sense were significantly decreased up to 48 h, whereas TTDPM decreased significantly at only one hour and 24 h after exercise, at 30 and 70 degrees of the knee flexion, respectively. The results allow the conclusion that eccentric exercise leading to muscle damage alters joint proprioception, suggesting that there might be impairment in the intrafusal fibres of spindle muscles and in the tendon organs.

  20. Skeletal muscle

    Science.gov (United States)

    There are approximately 650-850 muscles in the human body these include skeletal (striated), smooth and cardiac muscle. The approximation is based on what some anatomists consider separate muscle or muscle systems. Muscles are classified based on their anatomy (striated vs. smooth) and if they are v...

  1. Effects of whole-body vibration after eccentric exercise on muscle soreness and muscle strength recovery.

    Science.gov (United States)

    Timon, Rafael; Tejero, Javier; Brazo-Sayavera, Javier; Crespo, Carmen; Olcina, Guillermo

    2016-06-01

    [Purpose] The aim of this study was to investigate whether or not a single whole-body vibration treatment after eccentric exercise can reduce muscle soreness and enhance muscle recovery. [Subjects and Methods] Twenty untrained participants were randomly assigned to two groups: a vibration group (n=10) and control group (n=10). Participants performed eccentric quadriceps training of 4 sets of 5 repetitions at 120% 1RM, with 4 min rest between sets. After that, the vibration group received 3 sets of 1 min whole body vibration (12 Hz, 4 mm) with 30 s of passive recovery between sets. Serum creatine kinase, blood urea nitrogen, muscle soreness (visual analog scale) and muscle strength (peak isometric torque) were assessed. [Results] Creatine kinase was lower in the vibration group than in the control group at 24 h (200.2 ± 8.2 vs. 300.5 ± 26.1 U/L) and at 48 h (175.2 ± 12.5 vs. 285.2 ± 19.7 U/L) post-exercise. Muscle soreness decreased in vibration group compared to control group at 48 h post-exercise (34.1 ± 11.4 vs. 65.2 ± 13.2 mm). [Conclusion] Single whole-body vibration treatment after eccentric exercise reduced delayed onset muscle soreness but it did not affect muscle strength recovery.

  2. The impact of obesity on skeletal muscle strength and structure through adolescence to old age.

    Science.gov (United States)

    Tomlinson, D J; Erskine, R M; Morse, C I; Winwood, K; Onambélé-Pearson, Gladys

    2016-06-01

    Obesity is associated with functional limitations in muscle performance and increased likelihood of developing a functional disability such as mobility, strength, postural and dynamic balance limitations. The consensus is that obese individuals, regardless of age, have a greater absolute maximum muscle strength compared to non-obese persons, suggesting that increased adiposity acts as a chronic overload stimulus on the antigravity muscles (e.g., quadriceps and calf), thus increasing muscle size and strength. However, when maximum muscular strength is normalised to body mass, obese individuals appear weaker. This relative weakness may be caused by reduced mobility, neural adaptations and changes in muscle morphology. Discrepancies in the literature remain for maximal strength normalised to muscle mass (muscle quality) and can potentially be explained through accounting for the measurement protocol contributing to muscle strength capacity that need to be explored in more depth such as antagonist muscle co-activation, muscle architecture, a criterion valid measurement of muscle size and an accurate measurement of physical activity levels. Current evidence demonstrating the effect of obesity on muscle quality is limited. These factors not being recorded in some of the existing literature suggest a potential underestimation of muscle force either in terms of absolute force production or relative to muscle mass; thus the true effect of obesity upon skeletal muscle size, structure and function, including any interactions with ageing effects, remains to be elucidated.

  3. Muscle Deoxygenation Causes Muscle Fatigue

    Science.gov (United States)

    Murthy, G.; Hargens, A. R.; Lehman, S.; Rempel, D.

    1999-01-01

    Muscle fatigue is a common musculoskeletal disorder in the work place, and may be a harbinger for more disabling cumulative trauma disorders. Although the cause of fatigue is multifactorial, reduced blood flow and muscle oxygenation may be the primary factor in causing muscle fatigue during low intensity muscle exertion. Muscle fatigue is defined as a reduction in muscle force production, and also occurs among astronauts who are subjected to postural constraints while performing lengthy, repetitive tasks. The objectives of this research are to: 1) develop an objective tool to study the role of decreased muscle oxygenation on muscle force production, and 2) to evaluate muscle fatigue during prolonged glovebox work.

  4. Muscle disorder

    Science.gov (United States)

    Myopathic changes; Myopathy; Muscle problem ... Blood tests sometimes show abnormally high muscle enzymes. If a muscle disorder might also affect other family members, genetic testing may be done. When someone has symptoms and signs ...

  5. Quadriceps Tendon Rupture and Contralateral Patella Tendon Avulsion Post Primary Bilateral Total Knee Arthroplasty: A Case Report

    Directory of Open Access Journals (Sweden)

    Gaurav Sharma

    2016-07-01

    Full Text Available Background: Extensor mechanism failure secondary to knee replacement could be due to tibial tubercle avulsion, Patellar tendon rupture, patellar fracture or quadriceps tendon rupture. An incidence of Patella tendon rupture of 0.17% and Quadriceps tendon rupture of around 0.1% has been reported after Total knee arthroplasty. These are considered a devastating complication that substantially affects the clinical results and are challenging situations to treat with surgery being the mainstay of the treatment. Case Description: We report here an interesting case of a patellar tendon rupture of one knee and Quadriceps tendon rupture of the contralateral knee following simultaneous bilateral knee replacement in a case of inflammatory arthritis patient. End to end repair for Quadriceps tear and augmentation with Autologous Hamstring tendon graft was done for Patella tendon rupture. OUTCOME: Patient was followed up for a period of 1 year and there was no Extension lag with a flexion of 100 degrees in both the knees. DISCUSSION: The key learning points and important aspects of diagnosing these injuries early and the management techniques are described in this unique case of bilateral extensor mechanism disruption following knee replacements.

  6. Comparison of Lower Body Specific Resistance Training on the Hamstring to Quadriceps Strength Ratios in Men and Women

    Science.gov (United States)

    Dorgo, Sandor; Edupuganti, Pradeep; Smith, Darla R.; Ortiz, Melchor

    2012-01-01

    In this study, we compared hamstring (H) and quadriceps (Q) strength changes in men and women, as well as changes in conventional and functional H:Q ratios following an identical 12-week resistance training program. An isokinetic dynamometer was used to assess 14 male and 14 female participants before and after the intervention, and conventional…

  7. Neglected rupture of the quadriceps tendon in a patient with chronic renal failure (case report and review of the literature).

    Science.gov (United States)

    Hassani, Zouhir Ameziane; Boufettal, Moncef; Mahfoud, Moustapha; Elyaacoubi, Moradh

    2014-01-01

    Spontaneous ruptures of the quadriceps tendon are infrequent injuries, it is seen primarily in patients with predisposing diseases such as gout, rheumatoid arthritis and chronic renal failure. A 32-year-old man had a history of end stage renal disease and received regular hemodialysis treatment for more than 5 years. He was admitted in our service for total functional impotence of the right lower limb with knee pain after a common fall two months ago. The radiogram showed a ''patella baja" with suprapatellar calcifications. The ultrasound and MRI showed an aspect of rupture of the quadriceps tendon in its proximal end with retraction of 3 cm. Quadriceps tendon repair was performed with a lengthening plasty, and the result was satisfactory after a serial rehabilitation program. The diagnosis of quadriceps tendon ruptures needs more attention in patients with predisposing diseases. They should not be unknown because the treatment of neglected lesions is more difficult. We insist on the early surgical repair associated with early rehabilitation that can guarantee recovery of good active extension.

  8. Anterior Cruciate Ligament Injury: Compensation during Gait using Hamstring Muscle Activity.

    Science.gov (United States)

    Catalfamo, Paola Formento; Aguiar, Gerardo; Curi, Jorge; Braidot, Ariel

    2010-06-10

    Previous research has shown that an increase in hamstring activation may compensate for anterior tibial transalation (ATT) in patients with anterior cruciate ligament deficient knee (ACLd); however, the effects of this compensation still remain unclear. The goals of this study were to quantify the activation of the hamstring muscles needed to compensate the ATT in ACLd knee during the complete gait cycle and to evaluate the effect of this compensation on quadriceps activation and joint contact forces. A two dimensional model of the knee was used, which included the tibiofemoral and patellofemoral joints, knee ligaments, the medial capsule and two muscles units. Simulations were conducted to determine the ATT in healthy and ACLd knee and the hamstring activation needed to correct the abnormal ATT to normal levels (100% compensation) and to 50% compensation. Then, the quadriceps activation and the joint contact forces were calculated. Results showed that 100% compensation would require hamstring and quadriceps activations larger than their maximum isometric force, and would generate an increment in the peak contact force at the tibiofemoral (115%) and patellofemoral (48%) joint with respect to the healthy knee. On the other hand, 50% compensation would require less force generated by the muscles (less than 0.85 of maximum isometric force) and smaller contact forces (peak tibiofemoral contact force increased 23% and peak patellofemoral contact force decreased 7.5% with respect to the healthy knee). Total compensation of ATT by means of increased hamstring activity is possible; however, partial compensation represents a less deleterious strategy.

  9. [Morphohistochemical study of skeletal muscles in rats after experimental flight on "Kosmos-1887"].

    Science.gov (United States)

    Il'ina-Kakueva, E I

    1990-01-01

    Morphometric and histochemical methods were used to examine the soleus, gastrocnemius (medial portion), quadriceps femoris (central portion) and biceps brachii muscles of Wistar SPF rats two days after the 13-day flight on Cosmos-1887. It was found that significant atrophy developed only in the soleus muscle. The space flight did not change the percentage content of slow (type I) and fast (type II) fibers in fast twitch muscles. During two days at 1 g the slow soleus muscle developed substantial circulation disorders, which led to interstitial edema and necrotic changes. The gastrocnemius muscle showed small foci containing necrotic myofibers. Two days after recovery no glycogen aggregates were seen in myofibers, which were previously observed in other rats examined 4--8 hours after flight. An initial stage of muscle readaptation to 1 g occurred, when NAD.H2-dehydrogenase activity was decreased.

  10. Myoelectric fatigue profiles of three knee extensor muscles.

    Science.gov (United States)

    Botter, A; Lanfranco, F; Merletti, R; Minetto, M A

    2009-06-01

    Aims of the present study were to: 1) investigate the differences between the myoelectric fatigue profiles of the vasti muscles of the quadriceps during electrically evoked contractions; 2) compare the myoelectric fatigue profiles of the vasti muscles between sedentary subjects and rowers; 3) analyze motor unit activation order during stimulation of the vasti muscles. In nine sedentary subjects and nine rowers surface EMG signals were detected during electrically elicited contractions of the following three muscles: vastus medialis obliquus (VMO), vastus lateralis (VL), and vastus medialis longus (VML). M-waves were recorded as the muscles were stimulated with both variable (increasing-decreasing) and constant stimulation intensities. Changes in M-wave conduction velocity (CV) during trains with non-constant current were adopted for the study of the motor unit recruitment order. Rates of change of myoelectric signal variables were adopted to assess myoelectric manifestations of fatigue during stimulation trains with constant current. We found that: 1) VL muscle was more fatigable than vastus medialis muscles; 2) VL and VML muscles of rowers resulted less fatigable than sedentary subjects; and 3) in the three muscles, motor units tended to be recruited in order of increasing CV and derecruited in order of decreasing CV with increasing/decreasing stimulation current.

  11. Transcriptome-scale similarities between mouse and human skeletal muscles with normal and myopathic phenotypes

    Directory of Open Access Journals (Sweden)

    Kang Peter B

    2006-03-01

    Full Text Available Abstract Background Mouse and human skeletal muscle transcriptome profiles vary by muscle type, raising the question of which mouse muscle groups have the greatest molecular similarities to human skeletal muscle. Methods Orthologous (whole, sub- transcriptome profiles were compared among four mouse-human transcriptome datasets: (M six muscle groups obtained from three mouse strains (wildtype, mdx, mdx5cv; (H1 biopsied human quadriceps from controls and Duchenne muscular dystrophy patients; (H2 four different control human muscle types obtained at autopsy; and (H3 12 different control human tissues (ten non-muscle. Results Of the six mouse muscles examined, mouse soleus bore the greatest molecular similarities to human skeletal muscles, independent of the latters' anatomic location/muscle type, disease state, age and sampling method (autopsy versus biopsy. Significant similarity to any one mouse muscle group was not observed for non-muscle human tissues (dataset H3, indicating this finding to be muscle specific. Conclusion This observation may be partly explained by the higher type I fiber content of soleus relative to the other mouse muscles sampled.

  12. Outcomes following Hip and Quadriceps Strengthening Exercises for Patellofemoral Syndrome: A Systematic Review and Meta-Analysis

    Directory of Open Access Journals (Sweden)

    Adebisi Bisi-Balogun

    2015-10-01

    Full Text Available There is growing evidence to support change in the rehabilitation strategy of patellofemoral pain syndrome (PFPS from traditional quadriceps strengthening exercises to inclusion of hip musculature strengthening in individuals with PFPS. Several studies have evaluated effects of quadriceps and hip musculature strengthening on PFPS with varying outcomes on pain and function. This systematic review and meta-analysis aims to synthesize outcomes of pain and function post-intervention and at follow-up to determine whether outcomes vary depending on the exercise strategy in both the short and long term. Electronic databases including MEDLINE, EMBASE, CINAHL, Web of Science, PubMed, Pedro database, Proquest, Science direct, and EBscoHost databases were searched for randomized control trials published between 1st of January 2005 and 31st of June 2015, comparing the outcomes of pain and function following quadriceps strengthening and hip musculature strengthening exercises in patients with PFPS. Two independent reviewers assessed each paper for inclusion and quality. Means and SDs were extracted from each included study to allow effect size calculations and comparison of results. Six randomized control trials met the inclusion criteria. Limited to moderate evidence indicates that hip abductor strengthening was associated with significantly lower pain post-intervention (SMD −0.88, −1.28 to −0.47 95% CI, and at 12 months (SMD −3.10, −3.71 to −2.50 95% CI with large effect sizes (greater than 0.80 compared to quadriceps strengthening. Our findings suggest that incorporating hip musculature strengthening in management of PFPS tailored to individual ability will improve short-term and long-term outcomes of rehabilitation. Further research evaluating the effects of quadriceps and hip abductors strengthening focusing on reduction in anterior knee pain and improvement in function in management of PFPS is needed.

  13. Effect of 3 Different Applications of Kinesio Taping Denko® on Electromyographic Activity: Inhibition or Facilitation of the Quadriceps of Males During Squat Exercise

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    Júlio C. Serrão, Bruno Mezêncio, João G. Claudino, Rafael Soncin, Pedro L. Sampaio Miyashiro, Eric P. Sousa, Eduardo Borges, Vinícius Zanetti, Igor Phillip, Luiz Mochizuki, Alberto C. Amadio

    2016-09-01

    Full Text Available Kinesio taping consists of a technique which uses the application of an elastic adhesive tape. It has become a widely used rehabilitation modality for the prevention and treatment of musculoskeletal disorders. The objective of this study was to verify the effect of the application of Kinesio Taping Denko® in three conditions (facilitation, inhibition, and placebo on the electromyographic activity of the quadriceps and hamstrings muscles on facilitating or inhibiting the muscle function and on the perceived exertion during the barbell back squat exercise in healthy male subjects. Methods: It was a randomized, single-blinded and controlled study in which 18 males (28.0 ± 6.7 years old; 85.8 ± 8.2 kg mass; 1.80 ± 0.07 m tall; 0.97 ± 0.04 m lower limb length performed barbell back squat exercise with different conditions of Kinesio Taping Denko® applications: Facilitation, inhibition and placebo. Previous to the mentioned conditions, all individuals were assessed without applying kinesio Taping Denko® during the exercise. OMNI scale was used after each set for perceived exertion evaluation. No differences (p < 0.05 in the electromyographic activity of the biceps femoris, vastus lateralis and vastus medialis or OMNI scale were recorded under any conditions. Conclusion: The results show that the kinesio taping denko®may not alter the magnitude of the electromyography activity of vastus lateralis, vastus medialis, and biceps femoris during the squat exercise. Furthermore, the perceived exertion was not affected by the kinesio taping denko® application.

  14. Sensory and Motor Peripheral Nerve Function and Longitudinal Changes in Quadriceps Strength

    DEFF Research Database (Denmark)

    Ward, R. E.; Boudreau, R. M.; Caserotti, P.

    2015-01-01

    = 76.3 +/- 2.8, body mass index = 27.2 +/- 4.6 kg/m(2), strength = 96.3 +/- 34.7 Nm, 51.0% female, 34.8% black) from the Health ABC study. Isokinetic quadriceps strength was measured semiannually over 6 years. Peroneal motor nerve conduction amplitude and velocity were recorded. Sensory nerve function......Background. Poor peripheral nerve function is common in older adults and may be a risk factor for strength decline, although this has not been assessed longitudinally. Methods. We assessed whether sensorimotor peripheral nerve function predicts strength longitudinally in 1,830 participants (age...... was assessed with 10-g and 1.4-g monofilaments and average vibration detection threshold at the toe. Lower-extremity neuropathy symptoms were self-reported. Results. Worse vibration detection threshold predicted 2.4% lower strength in men and worse motor amplitude and two symptoms predicted 2.5% and 8.1% lower...

  15. Anterior cruciate ligament injuries in snowboarders: a quadriceps-induced injury.

    Science.gov (United States)

    Davies, Hywel; Tietjens, Barry; Van Sterkenburg, Maayke; Mehgan, Andrew

    2009-09-01

    Anterior cruciate ligament (ACL) injuries in snowboarders are rare. However, in expert boarders landing big jumps, ACL injuries are occurring more frequently. We identified 35 snowboarders with an identical injury mechanism. All these patients were landing from a jump. All described a flat landing on a flexed knee with significant knee compression. In 31 of 35 boarders, it was the front knee that was injured. Only two riders felt there was any twisting component to their injury. We postulate that the ACL rupture is due to maximal eccentric quadriceps contraction, as the boarder resists a compressive landing. Internal tibial rotation of the front knee in the snowboarding stance results in preloading of the ACL predisposing to injury.

  16. Strength stimuli on the quadriceps femoris influences the physiological tremor of the index finger

    CERN Document Server

    Lainez, Miguel J A; Gallach, Jose E; Moras, Gerard; Ranz, Daniel; Toca-Herrera, Jose L

    2008-01-01

    The influence of fatiguing stimuli applied to the quadriceps femoris on the tremor of the index finger on sixteen healthy subjects has been investigated, by measuring the acceleration and the electromyography activity of the extensor digitorum at two different speeds. No significant changes in the basal condition could be measured at 0.52 rad/s. However, at 1.05 rad/s the tremor amplitude (12.23%, p<0.05) and the electromyography activity (20.19%, p<0.05) increased in the time domain. In the frequential domain, the peak associated to the acceleration increased in 26.30% (p<0.05), while the electromiography activity experienced an increase of 81.34% (p<0.05). The largest change in frequency took place in the range 7-17 Hz. The discussion of the results leads to the conclusion that the supraespinal mechanism is responsible for the measured effect.

  17. Iatrogenic retractile quadriceps fibrosis within children in Benin: Epidemiological, clinical, therapeutical aspects

    Directory of Open Access Journals (Sweden)

    A S Gbenou

    2013-01-01

    Full Text Available Background: In tropical countries, iatrogenic retractile quadriceps fibrosis (IRQF, the cause of walking handicap in children, is often the result of intraquadricipital injection of quinine salts. The aim of this review was to analyse the epidemiological, clinical, therapeutic aspects and outcome of IRQF in children admitted in three hospitals in Benin Republic. Patients and Methods: It was a 10-year retrospective, descriptive and analytic survey of IRQF, involving 81 children aged from 8 months to 15 years. Iterative mobilization of the knee (IMK or modified distal quadriceps plasty by Thompson-Payr′s technique (MDQTPT, with a POP on the knee in flexion position, was performed with additional functional rehabilitation. The results were evaluated on knee flexion gain and walking quality. Data were processed using Epi Info 3.2 software. Results: Patients′ average age was 7.60 years. Children of 6-10 years were most affected; sex ratio was 1.02. Lesions were unilateral (71.6% and bilateral (28.4%. The knees′ stiffness was in flexion (10.57%, rectitude (64.42% and recurvatum (25%. The amyotrophy of the thigh was found in 79.42 %. The IMK was successful in eight cases (7.69 % and the MDQTPT was done in 98 cases (94.23% associated with femoral osteotomy in 13 cases (12.50%. In post-surgical period, skin necrosis and fractures occurred respectively in 15.31% and 5.10%. Results were good in 92.31% of cases. Conclusions: IRQF in children do exist in our settings. The treatment that is based on MDQTPT associated to rehabilitation leads to acceptable outcome.

  18. [Association between carbonyl proteins and tumor necrosis factor alpha with muscle strength in young and older women: exploratory study].

    Science.gov (United States)

    Martínez Huenchullán, Sergio Francisco; Mancilla Solorza, Eladio Bernabé

    2015-01-01

    It has recently been proposed that there is a close relationship between oxidative stress and low-grade chronic inflammation. Both processes have been related separately to muscle function in older adults (OA). Nevertheless, it still has not been determined if this relationship is present particularly in OA. The objective of this study was to determine the relationship between the plasma levels of TNF-α and carbonyl proteins (CP) and muscle strength in a group of young and older women. An exploratory study was conducted on 13 older and 8 young women, in whom the plasma levels of CP and TNF-α were measured. Muscle strength was measured by handgrip test, quadriceps voluntary maximal isometric strength, arm curl, and the 30 second sit to stand test. There were no differences in the plasma levels of CP and TNF-α between the groups, but there was relationship between the biomarkers only in the OA group. A non-linear relationship was observed between CP and quadriceps voluntary maximal isometric strength only in the OA group (R(2)=36.2; P=.038). For TNF-α there were no significant association with any of the applied tests. There is an association between CP and quadriceps voluntary maximal isometric strength only in the OA group, which could indicate a deleterious action of oxidative stress on muscle function, particularly in aging. Copyright © 2015 SEGG. Published by Elsevier Espana. All rights reserved.

  19. Blunted Myoglobin and Quadriceps Soreness after Electrical Stimulation during the Luteal Phase or Oral Contraception

    Science.gov (United States)

    Anderson, Lindsey J.; Baker, Lucinda L.; Schroeder, E. Todd

    2017-01-01

    Purpose: Acute muscle damage after exercise triggers subsequent regeneration, leading to hypertrophy and increased strength after repeated exercise. It has been debated whether acute exercise-induced muscle damage is altered under various premenopausal estrogen conditions. Acute contraction-induced muscle damage was compared during exogenous (oral…

  20. Fatigue during dynamic muscle contractions in male sprinters and marathon runners: relationships between performance, electromyographic activity, muscle cross-sectional area and morphology.

    Science.gov (United States)

    Lorentzon, R; Johansson, C; Sjöström, M; Fagerlund, M; Fugl-Meyer, A R

    1988-04-01

    Knee extensor fatigue and endurance during repeated maximum isokinetic manoeuvres were studied in five sprinters and five marathon runners, all males. Fatigue and endurance were expressed in terms of output (contractional work, CW) and input (integrated electromyograms, iEMG), and was related to muscle fibre composition of m. vastus lateralis and to cross-sectional area (CSA) of m. quadriceps. The initially performed contractional work was positively related to the calculated absolute type II fibre area of m. vastus lateralis, but not to the cross-sectional area of m. quadriceps. During the first 25 contractions, sprinters fatigued, with a slope of decline in contractional work that was correlated to the absolute type II fibre area, also after correction of performed work for CSA of m. quadriceps. As the electromyographic activity decreased less than the contractional work, a drastic fall in the CW/iEMG ratio was found in the sprinter group. Three out of five sprinters could perform less than 50 knee extensions, due to subjective discomfort in tested thighs. In contrast, all marathon runners could, after a minor similar decline in electromyographic activity and contractional work during the first part of the experiment, maintain a steady-state endurance level of CW and iEMG throughout the test (200 knee extensions). In conclusion, fatigue during isokinetic maximal knee extensions is closely related to the muscle structure of m. vastus lateralis.

  1. The presence of disease-associated prion protein in skeletal muscle of cattle infected with classical bovine spongiform encephalopathy.

    Science.gov (United States)

    Okada, Hiroyuki; Miyazawa, Kohtaro; Fukuda, Shigeo; Iwamaru, Yoshifumi; Imamura, Morikazu; Masujin, Kentaro; Matsuura, Yuichi; Fujii, Takashi; Fujii, Kei; Kageyama, Soichi; Yoshioka, Miyako; Murayama, Yuichi; Yokoyama, Takashi

    2014-01-01

    The aim of this study was to investigate the presence of disease-associated prion protein (PrP(Sc)) in the skeletal muscle of cattle infected with classical bovine spongiform encephalopathy (C-BSE). The study was carried out systematically in 12 different muscle samples from 43 (3 field and 40 experimental) cases of C-BSE; however, muscle spindles were not available in many of these cases. Therefore, analysis became restricted to a total of 31 muscles in 23 cattle. Even after this restriction, low levels of PrP(Sc) were detected in the muscle spindles of the masseter, intercostal, triceps brachii, psoas major, quadriceps femoris and semitendinosus muscles from 3 field and 6 experimental clinical-stage cases. The present data indicate that small amounts of PrP(Sc) are detectable by immunohistochemistry in the skeletal muscles of animals terminally affected with C-BSE.

  2. Electromyographical characteristics and muscle utilization in hemiplegic patients during sit-to-stand activity: an observational study.

    Science.gov (United States)

    Lu, Rong R; Li, Fang; Zhu, Bing

    2016-04-01

    Sit-to-stand is an important process in daily activity, and stroke patients have difficulty completing this task due to many reasons. To investigate the characteristic of muscle utilization of lower limb muscles between healthy participants and hemiplegic patients during sit-to-stand activity. This is an observational study. Inpatients at a rehabilitation hospital. Thirty-two stroke patients and 36 healthy participants. The participants were evaluated on sit-to-stand movement. Muscle strength was assessed by measuring maximal voluntary contraction (MVC) bilaterally in quadriceps, hamstrings, tibialis anterior and gastrocnemius. Amplitude (average and maximal) and area under the curve (AUC) of quadriceps, hamstring, tibialis anterior, and gastrocnemius of both sides were recorded during this activity. The average and maximal amplitudes of paretic muscles were significantly less than non-paretic muscles and healthy controls (Psit-to-stand activity in hemiplegic patients. During sit-to-stand, stroke patients' muscle utilization of both sides increased and MUR of the paretic side is similar to the non-paretic side. Muscle utilization ratio might help to understand how patients fulfill the sit-to-stand task. Using this information might improve our training strategy. Through customized training, paretic patients could fulfill the task with less muscle utilization.

  3. Heterogeneity of muscle activity during sedentary behavior.

    Science.gov (United States)

    Pesola, Arto J; Laukkanen, Arto; Tikkanen, Olli; Finni, Taija

    2016-11-01

    Replacing sitting by standing has been hypothesized to reduce the health risks of sitting, based on the assumption that muscles are passive during sitting and active during standing. Interventions have been more effective in overweight (OW) than in normal weight (NW) individuals, but subjects' muscle activities have not been quantified. This study compared quadriceps and hamstring muscle electromyographic (EMG) activity between 57 NW (body mass index (BMI) 22.5 ± 1.5 kg/m(2), female n = 36) and 27 OW (BMI 28.4 ± 2.9 kg/m(2), female n = 8) subjects during non-fatiguing standing (15 s, EMGstanding) and sitting (30 min). EMG amplitude was normalized to EMG measured during maximal isometric knee extension and flexion (% EMGMVC), and sitting muscle inactivity and bursts were determined using 4 thresholds (60% or 90% EMGstanding and 1% or 2% EMGMVC). Comparisons were adjusted for sex, age, knee extension strength, and the individual threshold. Standing EMG amplitude was 36% higher in OW (1.9% ± 1.5% EMGMVC) than in NW (1.4% ± 1.4% EMGMVC, P < 0.05) subjects. During sitting, muscles were inactive 89.8% ± 12.7% of the measurement time with 12.7 ± 14.2 bursts/min across all thresholds. On average, 6% more activity was recorded in NW than in OW individuals for 3 of the 4 thresholds (P < 0.05 for 60% or 90% EMGstanding and 1% EMGMVC). In conclusion, the OW group had higher muscle activity amplitude during standing but more muscle inactivity during sitting for 3/4 of the thresholds tested. Interventions should test whether the observed heterogeneity in muscle activity affects the potential to gain cardiometabolic benefits from replacing sitting with standing.

  4. 脊神经前根吻合重建脊髓损伤大鼠的股四头肌功能*★%Reconstruction of quadriceps femoris by anatomizing the ventral roots of spinal nerves in rats with spinal cord injury

    Institute of Scientific and Technical Information of China (English)

    李伟; 钟贵彬

    2013-01-01

      BACKGROUND: Reconstruction of motor function of limbs in spinal cord injury is significant for patients with paraplegia. OBJECTIVE: To recover the innervations and muscle contraction function of quadriceps femoris in spinal cord injured rats by constructing the neural pathway using the ventral roots of spinal nerves above injured segment of spinal cord and lumbar nerve that dominates the quadriceps femoris. METHODS: L 1 ventral root was anatomized to L 3 ventral root from Sprague-Dawley rats. After 6 months, axonal regeneration was found from L 1 ventral root to L 3 ventral root through the grafting nerve, which may reconstruct muscle contraction function. After nerve suture for 6 months, spinal cord injury was made in L 2 segment for neuroelectrophysiology examination to observe innervation of quadriceps femoris. RESULTS AND CONCLUSION: After semi-dissection of L 2 segment, wave from quadriceps femoris was recorded in electromyogram meter when stimulating the grafting nerve. After injured the segment of L 2 , we also record wave from quadriceps femoris when stimulating L 1 ventral root. Results showed that anastomosis of the L 1 ventral roots of spinal nerves above injured segment of spinal cord and the ventral root below the injured spinal cord segment can reconstruct the reflex path of innervation of quadriceps femoris, and the reflex center of quadriceps femoris in the spinal cord moves up to L 1 segment.%  背景:如何重建脊髓损伤肢体运动功能对截瘫患者具有重要的意义。目的:探索利用脊髓损伤平面以上健存的脊神经前根与支配股四头肌的腰神经建立神经通路,恢复脊髓损伤后股四头肌的神经支配和肌收缩功能。方法:对清洁级SD大鼠L1神经根的前根与L3神经根的前根进行显微吻合。经一段时间(6个月)的轴突再生后,期望建立新的肌肉收缩功能。神经缝合后6个月,在破坏L2脊髓节段前后,分别进行神经电生理检测,

  5. Strength Training to Contraction Failure Increases Voluntary Activation of the Quadriceps Muscle Shortly After Total Knee Arthroplasty

    DEFF Research Database (Denmark)

    Mikkelsen, Elin Karin; Jakobsen, Thomas Linding; Holsgaard-Larsen, Anders;

    2016-01-01

    to the abstract to increase trial transparency.This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed...

  6. Pro-inflammatory macrophages increase in skeletal muscle of high fat-fed mice and correlate with metabolic risk markers in humans.

    Science.gov (United States)

    Fink, Lisbeth N; Costford, Sheila R; Lee, Yun S; Jensen, Thomas E; Bilan, Philip J; Oberbach, Andreas; Blüher, Matthias; Olefsky, Jerrold M; Sams, Anette; Klip, Amira

    2014-03-01

    In obesity, immune cells infiltrate adipose tissue. Skeletal muscle is the major tissue of insulin-dependent glucose disposal, and indices of muscle inflammation arise during obesity, but whether and which immune cells increase in muscle remain unclear. Immune cell presence in quadriceps muscle of wild type mice fed high-fat diet (HFD) was studied for 3 days to 10 weeks, in CCL2-KO mice fed HFD for 1 week, and in human muscle. Leukocyte presence was assessed by gene expression of lineage markers, cyto/chemokines and receptors; immunohistochemistry; and flow cytometry. After 1 week HFD, concomitantly with glucose intolerance, muscle gene expression of Ly6b, Emr1 (F4/80), Tnf, Ccl2, and Ccr2 rose, as did pro- and anti-inflammatory markers Itgax (CD11c) and Mgl2. CD11c+ proinflammatory macrophages in muscle increased by 76%. After 10 weeks HFD, macrophages in muscle increased by 47%. Quadriceps from CCL2-KO mice on HFD did not gain macrophages and maintained insulin sensitivity. Muscle of obese, glucose-intolerant humans showed elevated CD68 (macrophage marker) and ITGAX, correlating with poor glucose disposal and adiposity. Mouse and human skeletal muscles gain a distinct population of inflammatory macrophages upon HFD or obesity, linked to insulin resistance in humans and CCL2 availability in mice. © 2013 The Obesity Society.

  7. Effects of cold water immersion on the recovery of physical performance and muscle damage following a one-off soccer match.

    Science.gov (United States)

    Ascensão, António; Leite, Marco; Rebelo, António N; Magalhäes, Sérgio; Magalhäes, José

    2011-02-01

    The aim of this study was to assess the effects of a single session of cold or thermoneutral water immersion after a one-off match on muscular dysfunction and damage in soccer players. Twenty-male soccer players completed one match and were randomly divided into cryotherapy (10 min cold water immersion, 10°C, n = 10) and thermoneutral (10 min thermoneutral water immersion, 35°C, n = 10) groups. Muscle damage (creatine kinase, myoglobin), inflammation (C-reactive protein), neuromuscular function (jump and sprint abilities and maximal isometric quadriceps strength), and delayed-onset muscle soreness were evaluated before, within 30 min of the end, and 24 and 48 h after the match. After the match, the players in both groups showed increased plasma creatine kinase activity (30 min, 24 h, 48 h), myoglobin (30 min) and C-reactive protein (30 min, 24 h) concentrations. Peak jump ability and maximal strength were decreased and delayed-onset muscle soreness increased in both groups. However, differential alterations were observed between thermoneutral water and cold water immersion groups in creatine kinase (30 min, 24 h, 48 h), myoglobin (30 min), C-reactive protein (30 min, 24 h, 48 h), quadriceps strength (24 h), and quadriceps (24 h), calf (24 h) and adductor (30 min) delayed-onset muscle soreness. The results suggest that cold water immersion immediately after a one-off soccer match reduces muscle damage and discomfort, possibly contributing to a faster recovery of neuromuscular function.

  8. Simultaneous bilateral quadriceps tendon rupture in a patient with hyperparathyroidism undergoing long-term haemodialysis: a case report and literature review.

    Science.gov (United States)

    Gao, Mao-Feng; Yang, Hui-Lin; Shi, Wei-Dong

    2013-08-01

    Simultaneous bilateral quadriceps tendon rupture is a rare injury that represents quadriceps tendon ruptures. It is generally associated with chronic metabolic disorders and is seen in patients with uraemia undergoing maintenance haemodialysis. The present case was a 46-year-old man who presented with pain and the inability to extend his knees following a minor accident. A physical examination combined with X-radiography and magnetic resonance imaging investigations resulted in a diagnosis of bilateral quadriceps tendon rupture. He had a history of uraemia and had received regular haemodialysis for 7 years. He had high levels of serum parathyroid hormone and he was diagnosed with secondary hyperparathyroidism. Following surgical repair of both quadriceps tendons, in addition to management of the secondary hyperparathyroidism, the patient regained full active mobility of both knee joints and was able to participate in normal activities of daily living.

  9. [Selective training of the vastus medialis muscle using electrical stimulator for chondromalacia patella].

    Science.gov (United States)

    Guo, K; Ye, Q; Lin, J; Shen, J; Yang, X

    1996-04-01

    Chondromalacia patella is closely related with subluxation and tilt of patella, as well as with muscular atrophy of quadriceps, especially in vastus medialis muscle. 364 cases of chondromalacia patella were treated with selective training of the vastus medialis muscle using electrical stimulator in our hospital. 211 cases were followed up after treatment from 6 months to 3 years. Among them excellent and good results were seen in 130 cases (62%), fair results were seen in 69 cases (33%) and no change was seen in 12 cases (5%). Significant reduction of CA (P chondromalacia patella.

  10. Changes in muscle force-length properties affect the early rise of force in vivo

    DEFF Research Database (Denmark)

    Blazevich, Anthony J; Cannavan, Dale; Horne, Sara

    2009-01-01

    Changes in contractile rate of force development (RFD), measured within a short time interval from contraction initiation, were measured after a period of strength training that led to increases in muscle fascicle length but no measurable change in neuromuscular activity. The relationship between...... training-induced shifts in the moment-angle relation and changes in RFD measured to 30 ms (i.e., early) and 200 ms (i.e., late) from the onset of isometric knee extension force were examined; shifts in the moment-angle relation were used as an overall measure of changes in quadriceps muscle fascicle length...

  11. Increased Plin2 Expression in Human Skeletal Muscle Is Associated with Sarcopenia and Muscle Weakness

    Science.gov (United States)

    Conte, Maria; Vasuri, Francesco; Trisolino, Giovanni; Bellavista, Elena; Santoro, Aurelia; Degiovanni, Alessio; Martucci, Ermanno; D’Errico-Grigioni, Antonia; Caporossi, Daniela; Capri, Miriam; Maier, Andrea B.; Seynnes, Olivier; Barberi, Laura; Musarò, Antonio; Narici, Marco V.; Franceschi, Claudio; Salvioli, Stefano

    2013-01-01

    Human aging is associated with a progressive loss of muscle mass and strength and a concomitant fat accumulation in form of inter-muscular adipose tissue, causing skeletal muscle function decline and immobilization. Fat accumulation can also occur as intra-muscular triglycerides (IMTG) deposition in lipid droplets, which are associated with perilipin proteins, such as Perilipin2 (Plin2). It is not known whether Plin2 expression changes with age and if this has consequences on muscle mass and strength. We studied the expression of Plin2 in the vastus lateralis (VL) muscle of both healthy subjects and patients affected by lower limb mobility limitation of different age. We found that Plin2 expression increases with age, this phenomenon being particularly evident in patients. Moreover, Plin2 expression is inversely correlated with quadriceps strength and VL thickness. To investigate the molecular mechanisms underpinning this phenomenon, we focused on IGF-1/p53 network/signalling pathway, involved in muscle physiology. We found that Plin2 expression strongly correlates with increased p53 activation and reduced IGF-1 expression. To confirm these observations made on humans, we studied mice overexpressing muscle-specific IGF-1, which are protected from sarcopenia. These mice resulted almost negative for the expression of Plin2 and p53 at two years of age. We conclude that fat deposition within skeletal muscle in form of Plin2-coated lipid droplets increases with age and is associated with decreased muscle strength and thickness, likely through an IGF-1- and p53-dependent mechanism. The data also suggest that excessive intramuscular fat accumulation could be the initial trigger for p53 activation and consequent loss of muscle mass and strength. PMID:23977392

  12. Increased Plin2 expression in human skeletal muscle is associated with sarcopenia and muscle weakness.

    Directory of Open Access Journals (Sweden)

    Maria Conte

    Full Text Available Human aging is associated with a progressive loss of muscle mass and strength and a concomitant fat accumulation in form of inter-muscular adipose tissue, causing skeletal muscle function decline and immobilization. Fat accumulation can also occur as intra-muscular triglycerides (IMTG deposition in lipid droplets, which are associated with perilipin proteins, such as Perilipin2 (Plin2. It is not known whether Plin2 expression changes with age and if this has consequences on muscle mass and strength. We studied the expression of Plin2 in the vastus lateralis (VL muscle of both healthy subjects and patients affected by lower limb mobility limitation of different age. We found that Plin2 expression increases with age, this phenomenon being particularly evident in patients. Moreover, Plin2 expression is inversely correlated with quadriceps strength and VL thickness. To investigate the molecular mechanisms underpinning this phenomenon, we focused on IGF-1/p53 network/signalling pathway, involved in muscle physiology. We found that Plin2 expression strongly correlates with increased p53 activation and reduced IGF-1 expression. To confirm these observations made on humans, we studied mice overexpressing muscle-specific IGF-1, which are protected from sarcopenia. These mice resulted almost negative for the expression of Plin2 and p53 at two years of age. We conclude that fat deposition within skeletal muscle in form of Plin2-coated lipid droplets increases with age and is associated with decreased muscle strength and thickness, likely through an IGF-1- and p53-dependent mechanism. The data also suggest that excessive intramuscular fat accumulation could be the initial trigger for p53 activation and consequent loss of muscle mass and strength.

  13. Skeletal muscle PGC-1a is required for maintaining an acute LPS-induced TNFa response

    DEFF Research Database (Denmark)

    Olesen, Jesper; Larsson, Signe; Iversen, Ninna;

    2012-01-01

    Many lifestyle-related diseases are associated with low-grade inflammation and peroxisome proliferator activated receptor ¿ coactivator (PGC)-1a has been suggested to be protective against low-grade inflammation. However, whether these anti-inflammatory properties affect acute inflammation...... does not exert anti-inflammatory effects during acute inflammation. Lack of skeletal muscle PGC-1a seems however to impair the acute TNFa response, which may reflect a phenotype more susceptible to infections as also observed in type 2 diabetes patients....... is not known. The aim of the present study was therefore to investigate the role of muscle PGC-1a in acute inflammation. Quadriceps muscles were removed from 10-week old whole body PGC-1a knockout (KO), muscle specific PGC-1a KO (MKO) and muscle-specific PGC-1a overexpression mice (TG), 2 hours after...

  14. The relationships between muscle force steadiness and visual steadiness in young and old adults.

    Science.gov (United States)

    Krupenevich, Rebecca L; Murray, Nick; Rider, Patrick M; Domire, Zachary J; DeVita, Paul

    2015-01-01

    Since vision is used in studies of muscle force control, reduced muscle force control might be related to reduced visual ability. We investigated relationships between steadiness in eye movements and quadriceps muscle torque (a surrogate for force) during isometric contractions of constant and varying torques. Nineteen young adults with an average age of 20.7 years and 18 old adults with an average age of 71.6 years performed three vision tasks, three vision and torque tasks at 40% maximal voluntary contraction (MVC), and three vision and torque tasks at 54 nm. Age groups had identical torque steadiness (CV) in 40%-MVC and 54-nm conditions (p > .05). Old had similar vertical (p > .05) but decreased horizontal visual steadiness (SD) (p .05). We were unable to identify a substantial relationship between muscle torque steadiness and eye movement, as a component of visual steadiness, and conclude that reduced visual steadiness does not contribute to reduced muscle torque steadiness.

  15. Reconstrução do ligamento cruzado posterior com enxerto autólogo do tendão do músculo semitendinoso duplo e do terço médio do tendão do quadríceps em duplo túnel no fêmur e único na tíbia: resultados clínicos em dois anos de seguimento Posterior cruciate ligament reconstruction with autograft of the double semitendinosus muscles and middle third of the quadriceps tendon with double femoral and single tibial tunnels: clinical results in two years follow up

    Directory of Open Access Journals (Sweden)

    Ricardo de Paula Leite Cury

    2012-02-01

    Full Text Available OBJETIVO: Avaliar os aspectos cirúrgicos que possam oferecer bons resultados anatômicos e funcionais na reconstrução do ligamento cruzado posterior (LCP utilizando enxerto autólogo do tendão do quadríceps e duplo semitendinoso através de um túnel femoral duplo. MÉTODOS: Quatorze pacientes com lesões isoladas do LCP, instabilidade e dor foram operados por artroscopia e avaliados de acordo com as escalas do International Knee Documentation Committee (IKDC e de Lysholm. A lassidão foi examinada com o artrômetro KT 1000. RESULTADOS: Na avaliação pós-operatória, a translação posterior comparando-se com joelho contralateral foi entre 0-2mm em 57,1% dos pacientes e entre 3 e 5mm em 35,7% dos casos. A média da escala de Lysholm foi de 93 pontos na avaliação final. Na avaliação pelo IKDC, três pacientes tiveram grau A, 10 grau B e 1 teve grau C. Conclusões: A reconstrução artroscópica do LCP com feixe duplo baseada no posicionamento anatômico dos túneis, com tendão duplo semitendinoso e único do quadríceps, oferece redução clinicamente evidente dos sintomas e recupera satisfatoriamente a estabilidade, embora diferença significativa não tenha sido encontrada devido ao pequeno tamanho da amostra.OBJECTIVE: To evaluate the surgical aspects that may offer good anatomic and functional results in posterior cruciate ligament (PCL reconstruction using an autologous graft of the quadriceps tendon and double semitendinosus through a double femoral tunnel. METHODS: Fourteen patients with isolated PCL lesions, instability and pain were operated on by arthroscopy and evaluated according to the International Knee Documentation Committee (IKDC and Lysholm scales. Posterior knee laxity was examined with a KT 1000 arthrometer. RESULTS: The mean postoperative posterior side-to-side difference was between 0-2 mm in 57.1% of patients and between 3 and 5 mm in 35.7% of cases. The average Lysholm score was 93 points in the final follow

  16. Long-lasting unilateral muscle wasting and weakness following injury and immobilisation.

    Science.gov (United States)

    Rutherford, O M; Jones, D A; Round, J M

    1990-01-01

    Quadriceps strength and size was measured in a small group of subjects (n = 7) 1 to 5 years after full mobilisation following some form of unilateral lower limb trauma. The mean maximum voluntary isometric force (MVC) was significantly lower for the injured (I) compared to the uninjured (UI) leg (369 N +/- 139 vs. 535 N +/- 131, p less than 0.01). Electrical stimulation superimposed on the voluntary contractions demonstrated that all subjects were able to maximally activate the quadriceps of both legs. Mean quadriceps cross-sectional area (CSA) was significantly lower in the I (64 cm2 +/- 12.8) compared to the UI leg (80 +/- 12.8, p less than 0.01). One subject with marked unilateral weakness and wasting took part in a 3-month strength training study for the injured leg. After training the I/UI ratio had been restored to nearly 100% (94% MVC; 88% CSA). These results would suggest that longer and more intensive physiotherapy is required in the immediate post-injury period to restore muscle strength and size to severely atrophied muscle.

  17. Validity of surface electromyography for vastus intermedius muscle assessed by needle electromyography.

    Science.gov (United States)

    Watanabe, Kohei; Akima, Hiroshi

    2011-06-15

    Recently, a new recording technique for surface electromyography (EMG) of the deeper muscle component of the quadriceps femoris muscle group, i.e., vastus intermedius (VI) muscle, from the distal portion of the VI muscle has been developed; however, the effect of electrode location on EMG signal of the VI muscle remains unclear. The aim of this study is to compare neuromuscular activation detected at the middle and distal portions of the VI muscle, in order to clarify whether the surface EMG of the VI muscle can be used to assess the neuromuscular activation of the entire muscle. Six healthy men participated in this study. During incremental ramp contraction of isometric knee extension (~30% of maximal voluntary contraction), needle EMG was recorded from the middle and distal regions of the VI muscle and surface EMG was performed at the distal region of the VI muscle. Excellent correlation was observed between needle EMG at the middle and distal regions (r=0.897-0.984, pEMG detected at the distal versus needle EMG detected at the middle and that of surface EMG detected at distal versus needle EMG detected at distal (pEMG at the distal portion of the VI muscle, which is the only region available for surface EMG, can be used to evaluate global neuromuscular activation of the VI muscle during isometric contraction at a low force level.

  18. Quadriceps tendon rupture: a biomechanical comparison of transosseous equivalent double-row suture anchor versus transosseous tunnel repair.

    Science.gov (United States)

    Hart, Nathan D; Wallace, Matthew K; Scovell, J Field; Krupp, Ryan J; Cook, Chad; Wyland, Douglas J

    2012-09-01

    Quadriceps rupture off the patella is traditionally repaired by a transosseous tunnel technique, although a single-row suture anchor repair has recently been described. This study biomechanically tested a new transosseous equivalent (TE) double-row suture anchor technique compared with the transosseous repair for quadriceps repair. After simulated quadriceps-patella avulsion in 10 matched cadaveric knees, repairs were completed by either a three tunnel transosseous (TT = 5) or a TE suture anchor (TE = 5) technique. Double-row repairs were done using two 5.5 Bio-Corkscrew FT (fully threaded) (Arthrex, Inc., Naples, FL, USA) and two 3.5 Bio-PushLock anchors (Arthrex, Inc., Naples, FL, USA) with all 10 repairs done with #2 FiberWire suture (Arthrex, Inc., Naples, FL). Cyclic testing from 50 to 250 N for 250 cycles and pull to failure load (1 mm/s) were undertaken. Gap formation and ultimate tensile load (N) were recorded and stiffness data (N/mm) were calculated. Statistical analysis was performed using a Mann-Whitney U test and survival characteristics examined with Kaplan-Meier test. No significant difference was found between the TE and TT groups in stiffness (TE = 134 +/- 15 N/mm, TT = 132 +/- 26 N/mm, p = 0.28). The TE group had significantly less ultimate tensile load (N) compared with the TT group (TE = 447 +/- 86 N, TT = 591 +/- 84 N, p = 0.04), with all failures occurring at the suture eyelets. Although both quadriceps repairs were sufficiently strong, the transosseous repairs were stronger than the TE suture anchor repairs. The repair stiffness and gap formation were similar between the groups.

  19. Use of a turndown quadriceps tendon flap for rupture of the patellar tendon after total knee arthroplasty.

    Science.gov (United States)

    Lin, Po-Chun; Wang, Jun-Wen

    2007-09-01

    Patellar tendon rupture is a devastating complication after total knee arthroplasty. The results of surgical treatment of this complication were discouraging in most of the reports. We describe a case of rupture of patellar tendon 7 weeks after total knee arthroplasty treated with a turndown quadriceps flap and circumferential wiring. Two years and 6 months after operation, the patient had no extension lag of the knee and knee flexion to 110 degrees .

  20. Spontaneous Rupture of the Patellar Tendon and the Contralateral Quadriceps Tendon, Associated with Lupus Erythematosus: Analysis of the Literature

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    Efthimios J. Karadimas

    2011-01-01

    Full Text Available Bilateral rupture of the patellar tendon is a rare injury. A case of a 67-year-old man with systemic lupus erythematosus under corticosteroid treatment for the last 10 years, who sustained spontaneous rupture of the patellar tendon and the contralateral quadriceps tendon, is herein presented. The patient was operated bilaterally, had an optimal outcome considering his age and the comorbidities, and was followed up for 24 months.

  1. Effectiveness of injury prevention programs on developing quadriceps and hamstrings strength of young male professional soccer players.

    Science.gov (United States)

    Daneshjoo, Abdolhamid; Rahnama, Nader; Mokhtar, Abdul Halim; Yusof, Ashril

    2013-12-18

    Muscular strength is an important factor which is crucial for performance and injury prevention in most sports. The purpose of this study was to evaluate the effects of the FIFA's Medical Assessment and Research Centre 11+ and HarmoKnee injury prevention programs on knee strength of young professional male soccer players. Thirty-six soccer players (age: 18.9 ± 1.4 years) were divided equally into three groups; the 11+, HarmoKnee and control groups. The programs were performed for 24 sessions. Hamstring and quadriceps strength was measured using the Biodex System 3 at 30°, 60° and 90° of knee flexion. The 11+ increased quadriceps strength in the dominant leg by 19.7% and 47.8% at 60°and 90° knee flexion, respectively, and in the non-dominant leg by 16%, 35.3% and 78.1 % at 30°, 60° and 90° knee flexion, respectively. The HarmoKnee group, however, showed increased quadriceps strength only at 90° i.e., by 85.7% in the dominant leg and 73.8% in the non-dominant leg. As for hamstring strength, only the 11+ group demonstrated an increment by 24.8% and 19.8% at 30° and 60° knee flexion in the dominant leg, and in the non-dominant leg, by 28.7% and 13.7% at 30° and 60° knee flexion, respectively. In conclusion, both warm-up programs improve quadriceps strength. The 11+ demonstrated improvement in hamstring strength while the HarmoKnee program did not indicate any improvement. We suggest adding eccentric hamstring components such as Nordic hamstring exercise to the HarmoKnee program in order to enhance hamstring strength.

  2. Vitamin D deficiency associates with γ-tocopherol and quadriceps weakness but not inflammatory cytokines in subjects with knee osteoarthritis.

    Science.gov (United States)

    Barker, Tyler; Henriksen, Vanessa T; Rogers, Victoria E; Aguirre, Dale; Trawick, Roy H; Lynn Rasmussen, G; Momberger, Nathan G

    2014-01-01

    Knee osteoarthritis (OA) is a degenerative joint condition and a leading cause of physical disability in the United States. Quadriceps weakness and inflammatory cytokines contribute to the pathogenesis of knee OA, and both of which, increase with vitamin D deficiency. Other micronutrients, such as vitamins C and E and β-carotene, modulate inflammatory cytokines and decrease during inflammation. The purpose of this study was to test the hypothesis that vitamin D deficiency associates with quadriceps weakness, an increase in serum cytokines, and a decrease in circulating micronutrients in subjects with knee OA. Subjects (age, 48±1 y; serum 25(OH)D, 25.8±1.1 ng/mL) with knee OA were categorized as vitamin D deficient (n=17; serum 25(OH)D≤20 ng/mL), insufficient (n=21; serum 25(OH)D 20-29 ng/mL), or sufficient (n=18; serum 25(OH)D≥30 ng/mL). Single-leg strength (concentric knee extension-flexion contraction cycles at 60 °/s) and blood cytokine, carotene (α and β), ascorbic acid, and tocopherol (α and γ) concentrations were measured. Quadriceps peak torque, average power, total work, and deceleration were significantly (all p<0.05) impaired with vitamin D deficiency. Serum γ-tocopherol concentrations were significantly (p<0.05) increased with vitamin D deficiency. In the vitamin D sufficient group, γ-tocopherol inversely correlated (r=-0.47, p<0.05) with TNF-α, suggesting a pro-inflammatory increase with a γ-tocopherol decrease despite a sufficient serum 25(OH)D concentration. We conclude that vitamin D deficiency is detrimental to quadriceps function, and in subjects with vitamin D sufficiency, γ-tocopherol could have an important anti-inflammatory role in a pathophysiological condition mediated by inflammation.

  3. Vitamin D deficiency associates with γ-tocopherol and quadriceps weakness but not inflammatory cytokines in subjects with knee osteoarthritis

    Directory of Open Access Journals (Sweden)

    Tyler Barker

    2014-01-01

    Full Text Available Knee osteoarthritis (OA is a degenerative joint condition and a leading cause of physical disability in the United States. Quadriceps weakness and inflammatory cytokines contribute to the pathogenesis of knee OA, and both of which, increase with vitamin D deficiency. Other micronutrients, such as vitamins C and E and β-carotene, modulate inflammatory cytokines and decrease during inflammation. The purpose of this study was to test the hypothesis that vitamin D deficiency associates with quadriceps weakness, an increase in serum cytokines, and a decrease in circulating micronutrients in subjects with knee OA. Subjects (age, 48±1 y; serum 25(OHD, 25.8±1.1 ng/mL with knee OA were categorized as vitamin D deficient (n=17; serum 25(OHD≤20 ng/mL, insufficient (n=21; serum 25(OHD 20–29 ng/mL, or sufficient (n=18; serum 25(OHD≥30 ng/mL. Single-leg strength (concentric knee extension–flexion contraction cycles at 60 °/s and blood cytokine, carotene (α and β, ascorbic acid, and tocopherol (α and γ concentrations were measured. Quadriceps peak torque, average power, total work, and deceleration were significantly (all p<0.05 impaired with vitamin D deficiency. Serum γ-tocopherol concentrations were significantly (p<0.05 increased with vitamin D deficiency. In the vitamin D sufficient group, γ-tocopherol inversely correlated (r=−0.47, p<0.05 with TNF-α, suggesting a pro-inflammatory increase with a γ-tocopherol decrease despite a sufficient serum 25(OHD concentration. We conclude that vitamin D deficiency is detrimental to quadriceps function, and in subjects with vitamin D sufficiency, γ-tocopherol could have an important anti-inflammatory role in a pathophysiological condition mediated by inflammation.

  4. Effect of cross exercise on quadriceps acceleration reaction time and subjective scores (Lysholm questionnaire following anterior cruciate ligament reconstruction

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    Antonogiannakis Emmanouel M

    2009-01-01

    Full Text Available Abstract Background Anterior cruciate ligament (ACL injury or reconstruction can cause knee impairments and disability. Knee impairments are related to quadriceps performance – accelerated reaction time (ART – and disability to performance of daily living activities which is assessed by questionnaires such as the Lysholm knee score. The purposes of this study were to investigate the effect of cross exercise, as supplementary rehabilitation to the early phase of ACL reconstruction: a on quadriceps ART at the angles 45°, 60° and 90° of knee flexion and, b on the subjective scores of disability in ACL reconstructed patients. Methods 42 patients who underwent ACL reconstruction were randomly divided into 3 groups, two experimental and one control. All groups followed the same rehabilitation program. The experimental groups followed 8 weeks of cross eccentric exercise (CEE on the uninjured knee; 3 d/w, and 5 d/w respectively. Quadriceps ART was measured at 45°, 60° and 90° of knee flexion pre and nine weeks post-operatively using an isokinetic dynamometer. Patients also completed pre and post operatively the Lysholm questionnaire whereby subjective scores were recorded. Results Two factor ANOVA showed significant differences in ART at 90° among the groups (F = 4.29, p = 0.02, p Significant differences were also found in the Lysholm score among the groups (F = 4.75, p = 0.01, p Conclusion CEE showed improvements on quadriceps ART at 90° at a sequence of 3 d/w and in the Lysholm score at a sequence of 3 d/w and 5 d/w respectively on ACL reconstructed patients.

  5. Anticonvulsant Effects of Fractions Isolated from Dinoponera quadriceps (Kempt Ant Venom (Formicidae: Ponerinae

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    Diana Aline Morais Ferreira Nôga

    2016-12-01

    Full Text Available Natural products, sources of new pharmacological substances, have large chemical diversity and architectural complexity. In this context, some toxins obtained from invertebrate venoms have anticonvulsant effects. Epilepsy is a neurological disorder that affects about 65 million people worldwide, and approximately 30% of cases are resistant to pharmacological treatment. Previous studies from our group show that the denatured venom of the ant Dinoponera quadriceps (Kempt protects mice against bicuculline (BIC-induced seizures and death. The aim of this study was to investigate the anticonvulsant activity of compounds isolated from D. quadriceps venom against seizures induced by BIC in mice. Crude venom was fractionated by high-performance liquid chromatography (HPLC resulting in six fractions referred to as DqTx1–DqTx6. A liquid chromatography-mass spectrometry (LC/MS analysis revealed a major 431 Da compound in fractions DqTx1 and DqTx2. Fractions DqTx3 and DqTx4 showed a compound of 2451 Da and DqTx5 revealed a 2436 Da compound. Furthermore, the DqTx6 fraction exhibited a major component with a molecular weight of 13,196 Da. Each fraction (1 mg/mL was microinjected into the lateral ventricle of mice, and the animals were observed in an open field. We did not observe behavioral alterations when the fractions were given alone. Conversely, when the fractions were microinjected 20 min prior to the administration of BIC (21.6 nM, DqTx1, DqTx4, and DqTx6 fractions increased the latency for onset of tonic-clonic seizures. Moreover, all fractions, except DqTx5, increased latency to death. The more relevant result was obtained with the DqTx6 fraction, which protected 62.5% of the animals against tonic-clonic seizures. Furthermore, this fraction protected 100% of the animals from seizure episodes followed by death. Taken together, these findings indicate that compounds from ant venom might be a potential source of new anticonvulsants molecules.

  6. Anticonvulsant Effects of Fractions Isolated from Dinoponera quadriceps (Kempt) Ant Venom (Formicidae: Ponerinae).

    Science.gov (United States)

    Nôga, Diana Aline Morais Ferreira; Brandão, Luiz Eduardo Mateus; Cagni, Fernanda Carvalho; Silva, Delano; de Azevedo, Dina Lilia Oliveira; Araújo, Arrilton; Dos Santos, Wagner Ferreira; Miranda, Antonio; da Silva, Regina Helena; Ribeiro, Alessandra Mussi

    2016-12-23

    Natural products, sources of new pharmacological substances, have large chemical diversity and architectural complexity. In this context, some toxins obtained from invertebrate venoms have anticonvulsant effects. Epilepsy is a neurological disorder that affects about 65 million people worldwide, and approximately 30% of cases are resistant to pharmacological treatment. Previous studies from our group show that the denatured venom of the ant Dinoponera quadriceps (Kempt) protects mice against bicuculline (BIC)-induced seizures and death. The aim of this study was to investigate the anticonvulsant activity of compounds isolated from D. quadriceps venom against seizures induced by BIC in mice. Crude venom was fractionated by high-performance liquid chromatography (HPLC) resulting in six fractions referred to as DqTx1-DqTx6. A liquid chromatography-mass spectrometry (LC/MS) analysis revealed a major 431 Da compound in fractions DqTx1 and DqTx2. Fractions DqTx3 and DqTx4 showed a compound of 2451 Da and DqTx5 revealed a 2436 Da compound. Furthermore, the DqTx6 fraction exhibited a major component with a molecular weight of 13,196 Da. Each fraction (1 mg/mL) was microinjected into the lateral ventricle of mice, and the animals were observed in an open field. We did not observe behavioral alterations when the fractions were given alone. Conversely, when the fractions were microinjected 20 min prior to the administration of BIC (21.6 nM), DqTx1, DqTx4, and DqTx6 fractions increased the latency for onset of tonic-clonic seizures. Moreover, all fractions, except DqTx5, increased latency to death. The more relevant result was obtained with the DqTx6 fraction, which protected 62.5% of the animals against tonic-clonic seizures. Furthermore, this fraction protected 100% of the animals from seizure episodes followed by death. Taken together, these findings indicate that compounds from ant venom might be a potential source of new anticonvulsants molecules.

  7. Differences in age-related fiber atrophy between vastii muscles of active subjects: a multichannel surface EMG study.

    Science.gov (United States)

    Boccia, Gennaro; Dardanello, Davide; Coratella, Giuseppe; Rinaldo, Nicoletta; Schena, Federico; Rainoldi, Alberto

    2015-07-01

    The aim of the study was to non-invasively determine if vastus lateralis (VL) and vastus medialis obliquus (VM) muscles are equally affected by age-related fiber atrophy. Multichannel surface electromyography was used since it allows to estimate muscle fiber conduction velocity (CV), which has been demonstrated to be related to the size of recruited muscle fibers. Twelve active elderly men (age 69   ±   4 years) and 12 active young men (age 23   ±   2 years) performed isometric knee extension at 30%, 50%, and 70% of maximal voluntary contraction. Electromyographic signals were recorded from VL and VM muscles of the dominant limb using arrays with eight electrodes and CVs were estimated for each contraction. CV estimates showed a different behavior in the two muscles: in VL at 50% and 70% of maximum voluntary contraction they were greater in young than in elderly; whereas such a difference was not observed in VM. This finding suggest that in active elderly VM seems to be less affected by the age-related fibers atrophy than VL. Hence, the common choice of studying VL as a muscle representative of the whole quadriceps could generate misleading findings. Indeed, it seemed that the sarcopenic ageing effects might be heterogeneous within quadriceps muscle.

  8. The effect of rowing ergometry and resistive exercise on skeletal muscle structure and function during bed rest.

    Science.gov (United States)

    Krainski, Felix; Hastings, Jeffrey L; Heinicke, Katja; Romain, Nadine; Pacini, Eric L; Snell, Peter G; Wyrick, Phil; Palmer, M Dean; Haller, Ronald G; Levine, Benjamin D

    2014-06-15

    Exposure to microgravity causes functional and structural impairment of skeletal muscle. Current exercise regimens are time-consuming and insufficiently effective; an integrated countermeasure is needed that addresses musculoskeletal along with cardiovascular health. High-intensity, short-duration rowing ergometry and supplemental resistive strength exercise may achieve these goals. Twenty-seven healthy volunteers completed 5 wk of head-down-tilt bed rest (HDBR): 18 were randomized to exercise, 9 remained sedentary. Exercise consisted of rowing ergometry 6 days/wk, including interval training, and supplemental strength training 2 days/wk. Measurements before and after HDBR and following reambulation included assessment of strength,