WorldWideScience

Sample records for purposethis study investigates

  1. Shape of magnifiers affects controllability in children with visual impairment

    NARCIS (Netherlands)

    Liebrand-Schurink, Joyce; Boonstra, F. Nienke; van Rens, Ger H. M. B.; Cillessen, Antonius H. N.; Meulenbroek, Ruud G. J.; Cox, Ralf F. A.

    2016-01-01

    PurposeThis study aimed to examine the controllability of cylinder-shaped and dome-shaped magnifiers in young children with visual impairment. MethodsThis study investigates goal-directed arm movements in low-vision aid use (stand and dome magnifier-like object) in a group of young children with

  2. Relationship of Total Motile Sperm Count and Percentage Motile Sperm to Successful Pregnancy Rates Following Intrauterine Insemination

    OpenAIRE

    Pasqualotto, Eleonora B.; Daitch, James A.; Hendin, Benjamin N.; Falcone, Tommaso; Thomas, Anthony J.; Nelson, David R.; Agarwal, Ashok

    1999-01-01

    Purpose:This study sought (i) to investigate the relationship between postwash total motile sperm count and postwash percentage motile sperm in predicting successful intrauterine insemination and (ii) to determine the minimal postwash total motile sperm count required to achieve pregnancy with intrauterine insemination.

  3. Practices and conditions which promote persistence of Listeria monocytogenes on equipment surfaces and transfer to cantaloupes in the packing environment

    Science.gov (United States)

    Introduction: Investigation of the 2011 U.S. listeriosis outbreak associated withcontaminated cantaloupes revealed that transfer of L. monocytogenes(Lm) from equipment surfaces to melons in the packing facility was a potential route of contamination. Purpose:This study examined the persistence of Lm...

  4. Haplotype-based approach for noninvasive prenatal tests of Duchenne muscular dystrophy using cell-free fetal DNA in maternal plasma

    DEFF Research Database (Denmark)

    Xu, Yan; Li, Xuchao; Ge, Hui-Juan

    2015-01-01

    Purpose:This study demonstrates noninvasive prenatal testing (NIPT) for Duchenne muscular dystrophy (DMD) using a newly developed haplotype-based approach.Methods:Eight families at risk for DMD were recruited for this study. Parental haplotypes were constructed using target-region sequencing data...

  5. Stock Versus CAD/CAM Customized Zirconia Implant Abutments - Clinical and Patient-Based Outcomes in a Randomized Controlled Clinical Trial

    NARCIS (Netherlands)

    Schepke, Ulf; Meijer, Henny J. A.; Kerdijk, Wouter; Raghoebar, Gerry M.; Cune, Marco

    BackgroundSingle-tooth replacement often requires a prefabricated dental implant and a customized crown. The benefits of individualization of the abutment remain unclear. PurposeThis randomized controlled clinical trial aims to study potential benefits of individualization of zirconia implant

  6. Different Imaging Strategies in Patients with Possible Basilar Artery Occlusion: Cost-Effectiveness Analysis

    NARCIS (Netherlands)

    S.E. Beyer (Sebastian E.); M.G.M. Hunink (Myriam); F. Schöberl (Florian); L. von Baumgarten; S.E. Petersen (Steffen); C. Kubisch (Christian); H. Janssen (Hendrik); B. Ertl-Wagner (Birgit); M.F. Reiser (Maximilian F.); W.H. Sommer (Wieland H.)

    2015-01-01

    textabstractBackground and Purpose-This study evaluated the cost-effectiveness of different noninvasive imaging strategies in patients with possible basilar artery occlusion. Methods-A Markov decision analytic model was used to evaluate long-term outcomes resulting from strategies using computed

  7. Demonstrating an approach for including pesticide use in life-cycle assessment: Estimating human and ecosystem toxicity of pesticide use in Midwest corn farming

    Science.gov (United States)

    PurposeThis study demonstrates an approach to assess human health and ecotoxicity impacts of pesticide use by including multiple environmental pathways and various exposure routes using the case of corn grown for bio-based fuel or chemical production in US Midwestern states.Metho...

  8. Principals' Opinions of Organisational Justice in Elementary Schools in Turkey

    Science.gov (United States)

    Aydin, Inayet; Karaman-Kepenekci, Yasemin

    2008-01-01

    Purpose--This study aims to present the opinions of public elementary school principals in Turkey about the current organisational justice practices among teachers from the distributive, procedural, interactional, and rectificatory dimensions. Design/methodology/approach--The opinions of 11 public elementary school principals in Ankara about…

  9. Persistence and transmission of Escherichia coli and Salmonella in a watermelon field ammended with poultry itter: year two

    Science.gov (United States)

    Introduction:Poultry litter (PL) is a nutrient-rich soil amendmentfor crop production; however, use of PL in soils may introduce enteric pathogens tofruits and vegetables. Purpose:This study was to evaluated the persistence of a non-pathogenic rifampicin-resistant E. coli strain (TVS 355) and the p...

  10. A life cycle greenhouse gas inventory of a tree production system

    Science.gov (United States)

    Alissa Kendall; E. Gregory McPherson

    2012-01-01

    PurposeThis study provides a detailed, process-based life cycle greenhouse gas (GHG) inventory of an ornamental tree production system for urban forestry. The success of large-scale tree planting initiatives for climate protection depends on projects being net sinks for CO2 over their entire life cycle....

  11. Birthdates of patients affected by mental illness and solar activity: A study from Italy

    Science.gov (United States)

    Ventriglio, Antonio; Borelli, Albacenzina; Bellomo, Antonello; Lepore, Alberto

    2011-04-01

    PurposeThis epidemiologic study tested an hypothesized association between the year of birth of persons with major mental illnesses and solar activity over the past century. MethodsWe collected data on diagnoses and birthdates of psychiatric patients born between 1926 and 1975 (N = 1954) in south Italy for comparison to yearly solar activity as registered by the International Observatories. ResultsWe found a strong inverse correlation between high solar activity (HSA) and incidence of schizophrenia and bipolar disorder in a 20-year period whereas the incidence of non-affective/non-psychotic disorders was moderately associated with HSA in the same period. ConclusionsInterpretation of the observed correlations between HSA during years of birth and the incidence of mental illnesses remains unclear, but the findings encourage further study.

  12. A life cycle carbon dioxide inventory of the Million Trees Los Angeles Program

    Science.gov (United States)

    E. Gregory McPherson; Alissa Kendall

    2014-01-01

    PurposeThis study seeks to answer the question, “Will the Million Trees LA (Million Trees Los Angeles, MTLA) program be a carbon dioxide (CO2) sink or source?” Because there has never been a full accounting of CO2 emissions, it is unclear if urban tree planting initiatives (TPIs) are likely to be...

  13. Aktivitas fisik dan konsumsi camilan pada remaja obesitas di pedesaan dan perkotaan Kabupaten Bantul

    OpenAIRE

    Irdianty, Mellia Silvy; Sudargo, Toto; Hakimi, Mohammad

    2018-01-01

    Physical activities and snack consumption of rural and urban obese adolescents in Bantul PurposeThis study to determine the difference of physical activity and snack consumption in adolescent obesity in urban and rural areas in the district of Bantul.MethodThis study used a case control study design, with a population of high school teenagers in Bantul. Cases are obese adolescents who were diagnosed at screening, while the control is not obese adolescents. Data analysis included univariable c...

  14. Urbanization effects on sediment and trace metals distribution in an urban winter pond (Netanya, Israel)

    NARCIS (Netherlands)

    Zohar, I.; Teutsch, N.; Levin, N.; Mackin, G.; de Stigter, H.; Bookman, R.

    2017-01-01

    PurposeThis paper aims to elucidate urban development-induced processes affecting the sediment and the distribution of contaminating metals in a seasonal pond located in the highly populated Israeli Coastal Plain. The paper demonstrates how an integrated approach, including geochemical,

  15. Designing and Managing a Strategic Academic Alliance: An Australian University Experience

    Science.gov (United States)

    Ryan, Lindsay; Morriss, Ross

    2005-01-01

    Purpose--This article outlines the experience and approach of an Australian university in developing and managing education program partnerships within industry. Design/methodology/approach--Describes how the university has established a specialist Strategic Partnerships unit for managing the customisation and delivery of postgraduate award…

  16. Aspirex Thrombectomy in Occluded Dialysis Access: A Retrospective Study

    Energy Technology Data Exchange (ETDEWEB)

    Dyer, Jules, E-mail: Jules.Dyer@nhs.net [New Cross Hospital, Department of Radiology (United Kingdom); Rosa, Joao [University Hospitals Bristol NHS Foundation Trust, ST1 Radiology (United Kingdom); Chachlani, Menka [University of Birmingham (United Kingdom); Nicholas, Johann [New Cross Hospital, Department of Radiology (United Kingdom)

    2016-10-15

    PurposeThis study is the first to present the outcomes of the Straub Aspirex device for the salvage of occluded renal dialysis access fistulae.Materials and MethodsThis is a retrospective study, using data from the Renal Unit and Radiology Department database. It included all the patients between 2010 and 2014 who underwent percutaneous mechanical thrombectomy (PMT) treated by JD. Aspirex is an over-the-wire, 6–10 French catheter within which is a rapidly rotating helix which draws thrombus into a window near the tip which it then macerates and removes. Access survival was assessed using the Kaplan–Meier method, and multi-variant analysis was performed using the Cox proportional hazards model. Significance was considered if p < 0.05.ResultsA total of 27 procedures were performed for 19 patients. 13 had autologous arterio-venous fistulae, and 14 had synthetic (PTFE) arterio-venous grafts. 15 were males, 4 females. 100 % of the patients successfully had a channel of thrombus removed. This resulted in an 81.5 % initial clinical success, with primary patency rates of 53.6, 44.3 and 33 % by days 30, 90 and 480, respectively, without significant difference of any analysed covariates. No major complication (pulmonary embolus, paradoxical cerebral infarction, limb ischaemia or significant haemorrhage) occurred.ConclusionAspirex has rates of patency and complication similar to other PMT devices. No covariant studied affected outcome.

  17. Older people’s forums in the United Kingdom:Civic engagement and activism reviewed

    OpenAIRE

    Manthorpe, Jill; Harris, Jessica; Mauger, Sam

    2016-01-01

    PurposeThis paper reviews the literature on UK older people’s forums. Forums seek to influence statutory responses to ageing, and enable older people to speak up on matters important to them. The review examined three facets of forums: their membership, structures and effectiveness.MethodsMethods included searching databases, internet and specialist libraries for materials relating to older people’s forums. Key points were extracted and source material described but not subject to quality app...

  18. Investigating educational research. A study on dissertations

    Directory of Open Access Journals (Sweden)

    Paulo Marcelo Marini Teixeira

    2006-08-01

    Full Text Available This paper is a brief historical survey on the emergence of educational research in Brazil, namely the rise and development of Science Education research, with special focus on research developed in Education and Science Education graduate programs. It highlights the relevance of the so-called ‘state-of-the-art” studies as a category of investigation that is fundamental for analytical studies on production in a given field of research, and addresses basic procedures to be carried out in investigations of this nature. Finally, this paper presents some trends in Biology Education research in Brazil as shown in Brazilian dissertations and theses produced between 1972 and 2003.

  19. Theoretical study of rock mass investigation efficiency

    International Nuclear Information System (INIS)

    Holmen, Johan G.; Outters, Nils

    2002-05-01

    The study concerns a mathematical modelling of a fractured rock mass and its investigations by use of theoretical boreholes and rock surfaces, with the purpose of analysing the efficiency (precision) of such investigations and determine the amount of investigations necessary to obtain reliable estimations of the structural-geological parameters of the studied rock mass. The study is not about estimating suitable sample sizes to be used in site investigations.The purpose of the study is to analyse the amount of information necessary for deriving estimates of the geological parameters studied, within defined confidence intervals and confidence level In other words, how the confidence in models of the rock mass (considering a selected number of parameters) will change with amount of information collected form boreholes and surfaces. The study is limited to a selected number of geometrical structural-geological parameters: Fracture orientation: mean direction and dispersion (Fisher Kappa and SRI). Different measures of fracture density (P10, P21 and P32). Fracture trace-length and strike distributions as seen on horizontal windows. A numerical Discrete Fracture Network (DFN) was used for representation of a fractured rock mass. The DFN-model was primarily based on the properties of an actual fracture network investigated at the Aespoe Hard Rock Laboratory. The rock mass studied (DFN-model) contained three different fracture sets with different orientations and fracture densities. The rock unit studied was statistically homogeneous. The study includes a limited sensitivity analysis of the properties of the DFN-model. The study is a theoretical and computer-based comparison between samples of fracture properties of a theoretical rock unit and the known true properties of the same unit. The samples are derived from numerically generated boreholes and surfaces that intersect the DFN-network. Two different boreholes are analysed; a vertical borehole and a borehole that is

  20. Radiofrequency Ablation Combined with Hepatic Arterial Chemoembolization Using Degradable Starch Microsphere Mixed with Mitomycin C for the Treatment of Liver Metastasis from Colorectal Cancer: A Prospective Multicenter Study

    International Nuclear Information System (INIS)

    Yamakado, Koichiro; Inaba, Yasutaka; Sato, Yozo; Yasumoto, Taku; Hayashi, Sadao; Yamanaka, Takashi; Nobata, Koji; Takaki, Haruyuki; Nakatsuka, Atsuhiro

    2017-01-01

    PurposeThis phase II prospective study investigates possible benefits of radiofrequency ablation (RFA) combined with hepatic arterial chemoembolization using degradable starch microsphere (DSM) mixed with mitomycin C (MMC) in non-surgical candidates with colorectal liver metastases.Materials and MethodsThis study, approved by the respective institutional review board, included non-surgical candidates with 3 or fewer liver tumors of 3 cm or smaller, or a single lesion 5 cm or smaller. Percutaneous RFA was performed immediately after chemoembolization using DSM-MMC. Primary and secondary endpoints were the local tumor control rate, safety, and 2-year recurrence-free and overall survival rates.ResultsThis study examined 25 patients (22 males, 3 females) with 38 tumors of mean maximum diameter of 2.2 ± 0.9 cm (standard deviation) (range 1.0–4.2 cm). Their mean age was 70.2 ± 8.2 years (range 55–82 years). Local tumor progression developed in 3 tumors (7.9%, 3/38) of 3 patients (12%, 3/25) during the mean follow-up of 34.9 ± 9.2 months (range 18.3–50.1 months). The 2-year local tumor control rates were 92.0% [95% confidence interval (CI), 81.4–100%] on a patient basis and 94.6% (95% CI, 87.3–100%) on a tumor basis. The respective 2-year overall and recurrence-free survival rates were 88.0% (95% CI, 75.3–98.5%) and 63.3% (95% CI, 44.2–82.5%), with median survival time of 48.4 months. Fever was the only adverse event requiring treatments in 2 patients (8%).ConclusionsThis combination therapy is safe, exhibiting strong anticancer effects on colorectal liver metastasis, which might contribute to patient survival.

  1. Radiofrequency Ablation Combined with Hepatic Arterial Chemoembolization Using Degradable Starch Microsphere Mixed with Mitomycin C for the Treatment of Liver Metastasis from Colorectal Cancer: A Prospective Multicenter Study

    Energy Technology Data Exchange (ETDEWEB)

    Yamakado, Koichiro, E-mail: yamakado47@gmail.com [Hyogo College of Medicine, Department of Radiology (Japan); Inaba, Yasutaka; Sato, Yozo [Aichi Cancer Center, Department of Radiology (Japan); Yasumoto, Taku [Toyonaka Municipal Hospital, Department of Radiology (Japan); Hayashi, Sadao [Kagoshima University, Department of Radiology (Japan); Yamanaka, Takashi [Mie University, Department of Radiology (Japan); Nobata, Koji [Kouseiren Takaoka Hospital, Department of Radiology (Japan); Takaki, Haruyuki [Hyogo College of Medicine, Department of Radiology (Japan); Nakatsuka, Atsuhiro [Mie University, Department of Radiology (Japan)

    2017-04-15

    PurposeThis phase II prospective study investigates possible benefits of radiofrequency ablation (RFA) combined with hepatic arterial chemoembolization using degradable starch microsphere (DSM) mixed with mitomycin C (MMC) in non-surgical candidates with colorectal liver metastases.Materials and MethodsThis study, approved by the respective institutional review board, included non-surgical candidates with 3 or fewer liver tumors of 3 cm or smaller, or a single lesion 5 cm or smaller. Percutaneous RFA was performed immediately after chemoembolization using DSM-MMC. Primary and secondary endpoints were the local tumor control rate, safety, and 2-year recurrence-free and overall survival rates.ResultsThis study examined 25 patients (22 males, 3 females) with 38 tumors of mean maximum diameter of 2.2 ± 0.9 cm (standard deviation) (range 1.0–4.2 cm). Their mean age was 70.2 ± 8.2 years (range 55–82 years). Local tumor progression developed in 3 tumors (7.9%, 3/38) of 3 patients (12%, 3/25) during the mean follow-up of 34.9 ± 9.2 months (range 18.3–50.1 months). The 2-year local tumor control rates were 92.0% [95% confidence interval (CI), 81.4–100%] on a patient basis and 94.6% (95% CI, 87.3–100%) on a tumor basis. The respective 2-year overall and recurrence-free survival rates were 88.0% (95% CI, 75.3–98.5%) and 63.3% (95% CI, 44.2–82.5%), with median survival time of 48.4 months. Fever was the only adverse event requiring treatments in 2 patients (8%).ConclusionsThis combination therapy is safe, exhibiting strong anticancer effects on colorectal liver metastasis, which might contribute to patient survival.

  2. Phase I/II Study of Radiofrequency Ablation for Malignant Renal Tumors: Japan Interventional Radiology in Oncology Study Group 0701

    International Nuclear Information System (INIS)

    Mimura, Hidefumi; Arai, Yasuaki; Yamakado, Koichiro; Sone, Miyuki; Takeuchi, Yoshito; Miki, Tsuneharu; Gobara, Hideo; Sakuhara, Yusuke; Yamamoto, Takanobu; Sato, Yozo; Kanazawa, Susumu

    2016-01-01

    PurposeThis multicenter phase I/II study evaluated the safety, feasibility, and initial efficacy of radiofrequency ablation (RFA) for small malignant renal tumors.MethodsThirty-three patients were enrolled in the study. A single session of RFA was performed in patients with a renal tumor of 1–3 cm in greatest diameter, with the exception of lesions adjacent to the renal hilum. The primary endpoint was the safety of renal RFA, and the secondary endpoints were its feasibility and initial efficacy for local control, as well as the incidence and grade of adverse events. Clinical efficacy was evaluated by CT scans within 1 week and at a further 4 weeks after the procedure using the criteria adapted from the Response Evaluation Criteria in Solid Tumors.ResultsThe RFA procedure was completed in 100 % (95 % confidence interval [CI] 89–100 %) of all 33 patients. There were no severe adverse events (0 % [95 % CI 0–11 %]). Among the 33 patients, a complete response, partial response, progressive disease, and stable disease were seen in 28 (85 %), 0 (0 %), one (3 %), and one (3 %) patient(s), respectively, with a tumor response rate of 85 % [95 % CI 68–95 %]). Three patients (9 %), including one ineligible patient (3 %), were not evaluable. Out of 30 evaluable patients, a complete response was achieved in 28 (93 %).ConclusionThe current multicenter trial revealed that RFA is a safe, feasible, and effective treatment for small malignant renal tumors in patients who are not candidates for surgery.

  3. Phase I/II Study of Radiofrequency Ablation for Malignant Renal Tumors: Japan Interventional Radiology in Oncology Study Group 0701

    Energy Technology Data Exchange (ETDEWEB)

    Mimura, Hidefumi, E-mail: mimura@marianna-u.ac.jp [St. Marianna University School of Medicine, Department of Radiology (Japan); Arai, Yasuaki, E-mail: arai-y3111@mvh.biglobe.ne.jp [National Cancer Center Hospital, Department of Diagnostic Radiology (Japan); Yamakado, Koichiro, E-mail: yama@clin.medic.mie-u.ac.jp [Mie University School of Medicine, Department of Interventional Radiology (Japan); Sone, Miyuki, E-mail: msone@me.com; Takeuchi, Yoshito, E-mail: yotake62@qg8.so-net.ne.jp [National Cancer Center Hospital, Department of Diagnostic Radiology (Japan); Miki, Tsuneharu, E-mail: tmiki@koto.kpu-m.ac.jp [Kyoto Prefectural University of Medicine, Department of Urology (Japan); Gobara, Hideo, E-mail: gobara@cc.okayama-u.ac.jp [Okayama University Medical School, Department of Radiology (Japan); Sakuhara, Yusuke, E-mail: yusaku@med.hokudai.ac.jp [Hokkaido University School of Medicine, Department of Diagnostic and Interventional Radiology (Japan); Yamamoto, Takanobu, E-mail: tyamamot@tcc.pref.tochigi.lg.jp [Tochigi Cancer Center, Department of Radiology (Japan); Sato, Yozo, E-mail: ysato@aichi-cc.jp [Aichi Cancer Center Hospital, Department of Diagnostic and Interventional Radiology (Japan); Kanazawa, Susumu, E-mail: susumu@cc.okayama-u.ac.jp [Okayama University Medical School, Department of Radiology (Japan)

    2016-05-15

    PurposeThis multicenter phase I/II study evaluated the safety, feasibility, and initial efficacy of radiofrequency ablation (RFA) for small malignant renal tumors.MethodsThirty-three patients were enrolled in the study. A single session of RFA was performed in patients with a renal tumor of 1–3 cm in greatest diameter, with the exception of lesions adjacent to the renal hilum. The primary endpoint was the safety of renal RFA, and the secondary endpoints were its feasibility and initial efficacy for local control, as well as the incidence and grade of adverse events. Clinical efficacy was evaluated by CT scans within 1 week and at a further 4 weeks after the procedure using the criteria adapted from the Response Evaluation Criteria in Solid Tumors.ResultsThe RFA procedure was completed in 100 % (95 % confidence interval [CI] 89–100 %) of all 33 patients. There were no severe adverse events (0 % [95 % CI 0–11 %]). Among the 33 patients, a complete response, partial response, progressive disease, and stable disease were seen in 28 (85 %), 0 (0 %), one (3 %), and one (3 %) patient(s), respectively, with a tumor response rate of 85 % [95 % CI 68–95 %]). Three patients (9 %), including one ineligible patient (3 %), were not evaluable. Out of 30 evaluable patients, a complete response was achieved in 28 (93 %).ConclusionThe current multicenter trial revealed that RFA is a safe, feasible, and effective treatment for small malignant renal tumors in patients who are not candidates for surgery.

  4. Adaptive error detection for HDR/PDR brachytherapy: Guidance for decision making during real-time in vivo point dosimetry

    DEFF Research Database (Denmark)

    Kertzscher Schwencke, Gustavo Adolfo Vladimir; Andersen, Claus E.; Tanderup, Kari

    2014-01-01

    Purpose:This study presents an adaptive error detection algorithm (AEDA) for real-timein vivo point dosimetry during high dose rate (HDR) or pulsed dose rate (PDR) brachytherapy (BT) where the error identification, in contrast to existing approaches, does not depend on an a priori reconstruction ......, and the AEDA’s capacity to distinguish between true and false error scenarios. The study further shows that the AEDA can offer guidance in decision making in the event of potential errors detected with real-time in vivo point dosimetry....... of the dosimeter position reconstruction. Given its nearly exclusive dependence on stable dosimeter positioning, the AEDA allows for a substantially simplified and time efficient real-time in vivo BT dosimetry implementation. Methods:In the event of a measured potential treatment error, the AEDA proposes the most...

  5. Iohexol in investigations of the spinal canal. Multicentre study

    International Nuclear Information System (INIS)

    Bories, J.

    1988-01-01

    The author presents the results of a multicentric study of Iohexol in investigation of the spinal canal undertaken at the request of Winthrop Laboratories in 32 Radiological departments. The study involved 329 adults of both sexes. It confirmed the excellent quality of results obtained with this preparation in the literature and its excellent tolerance. On the basis of these results Iohexol may be considered to be definitely one of the best currently available preparations for investigation of the spinal canal [fr

  6. Investigation of Sustainable Energy Policy: Nairobi Case Study

    Science.gov (United States)

    Shengyuan, Y.; Habiyaremye, J. F. L.; Yingying, W.

    2017-07-01

    A plan for actively achieving green energy obligation is a strategic tool for policies that point forward the diminution of the fossil fuel consumption and greenhouse gas (GHG) in conformity with the Paris environment-friendly accords (COP21) and updates of other ecosystem agreements. To achieve the concrete implementation of the sustainable energy strategy (SES) and to accomplish its objectives, an investigation is a critical factor. SES investigation has to consider both the advancement of each particular action and its wide-ranging green effect, which necessitates multiple levels of improvement. In this study, a consolidated eco strategy for evaluating, monitoring and handling the SES via investigation and execution process is established. The city of Nairobi was used as one of the geographical positions to test the effectiveness of this approach and to investigate its robust and weak points. Specifically, benefit-cost analysis, reliability, peer review and general level of participation were renowned as vital tools for attaining a functional SES investigation and for then drafting successful energy guidelines. Some suggestions were put forward to highlight the research and execution methods and to draw a road map of how SES can be strategically placed into practice.

  7. Structural investigations of substituted indolizine derivatives by NMR studies

    International Nuclear Information System (INIS)

    Furdui, Bianca; Dinica, Rodica; Demeunynck, Martine; Druta, Ioan

    2008-01-01

    Owing to the increasing importance of indolizine heterocycles in the field of biology and pharmacology we have synthesized and investigated the obtained heterocycles by NMR techniques. In order to investigate the substituent effects on the spectroscopic properties, a series of indolizine derivatives were studied by 1 H-NMR, 13 C-NMR and 2D NMR (GCOSY, GHMBC and GHMQC spectra). (authors)

  8. Oak Ridge National Laboratory remedial investigation/feasibility study

    International Nuclear Information System (INIS)

    Glenn, R.D.; Hoffman, J.M.; Hyde, L.D.

    1988-01-01

    The Oak Ridge National Laboratory (ORNL) Remedial Investigation/ Feasibility Study (RI/FS) began in June 1987 to evaluate 13 contaminated waste area groupings (WAGs) to determine the feasibility and benefits of potential remedial action. The RI/FS and any future remedial action at ORNL will be of national significance and will likely lead to developments that will become models for environmental investigations and cleanups. Bechtel National, Inc. and a team of subcontractors will be working with Martin Marietta Energy systems to conduct intensive field investigations to obtain data required to evaluate the WAGs. The RI/F project continued in FY 1988 with project planning and preparation for field activities. Remedial Investigation (RI) Plans were prepared for 10 of the 13 WAGs. These plans were developed with sufficient information to ensure compliance with regulatory requirements, with intensive attention given to environmental, safety, and health protection; waste management; data management; and quality assurance. This paper reports on the progress made during FY 1988 and discusses activities planned for FY 1989

  9. A comparative study of information diffusion in weblogs and microblogs based on social network analysis

    Institute of Scientific and Technical Information of China (English)

    Yang ZHANG; Wanyang LING

    2012-01-01

    Purpose:This paper intends to explore a quantitative method for investigating the characteristics of information diffusion through social media like weblogs and microblogs.By using the social network analysis methods,we attempt to analyze the different characteristics of information diffusion in weblogs and microblogs as well as the possible reasons of these differences.Design/methodology/approach:Using the social network analysis methods,this paper carries out an empirical study by taking the Chinese weblogs and microblogs in the field of Library and Information Science (LIS) as the research sample and employing measures such as network density,core/peripheral structure and centrality.Findings:Firstly,both bloggers and microbloggers maintain weak ties,and both of their social networks display a small-world effect.Secondly,compared with weblog users,microblog users are more interconnected,more equal and more capable of developing relationships with people outside their own social networks.Thirdly,the microblogging social network is more conducive to information diffusion than the blogging network,because of their differences in functions and the information flow mechanism.Finally,the communication mode emerged with microblogging,with the characteristics of micro-content,multi-channel information dissemination,dense and decentralized social network and content aggregation,will be one of the trends in the development of the information exchange platform in the future.Research limitations:The sample size needs to be increased so that samples are more representative.Errors may exist during the data collection.Moreover,the individual-level characteristics of the samples as well as the types of information exchanged need to be further studied.Practical implications:This preliminary study explores the characteristics of information diffusion in the network environment and verifies the feasibility of conducting a quantitative analysis of information diffusion through

  10. A comparative study of information diffusion in weblogs and microblogs based on social network analysis

    Institute of Scientific and Technical Information of China (English)

    Yang; ZHANG; Wanyang; LING

    2012-01-01

    Purpose:This paper intends to explore a quantitative method for investigating the characteristics of information diffusion through social media like weblogs and microblogs.By using the social network analysis methods,we attempt to analyze the different characteristics of information diffusion in weblogs and microblogs as well as the possible reasons of these differences.Design/methodology/approach:Using the social network analysis methods,this paper carries out an empirical study by taking the Chinese weblogs and microblogs in the field of Library and Information Science(LIS)as the research sample and employing measures such as network density,core/peripheral structure and centrality.Findings:Firstly,both bloggers and microbloggers maintain weak ties,and both of their social networks display a small-world effect.Secondly,compared with weblog users,microblog users are more interconnected,more equal and more capable of developing relationships with people outside their own social networks.Thirdly,the microblogging social network is more conducive to information diffusion than the blogging network,because of their differences in functions and the information flow mechanism.Finally,the communication mode emerged with microblogging,with the characteristics of micro-content,multi-channel information dissemination,dense and decentralized social network and content aggregation,will be one of the trends in the development of the information exchange platform in the future.Research limitations:The sample size needs to be increased so that samples are more representative.Errors may exist during the data collection.Moreover,the individual-level characteristics of the samples as well as the types of information exchanged need to be further studied.Practical implications:This preliminary study explores the characteristics of information diffusion in the network environment and verifies the feasibility of conducting a quantitative analysis of information diffusion through social

  11. A pilot investigation to optimise methods for a future satiety preload study

    OpenAIRE

    Hobden, Mark R.; Guérin-Deremaux, Laetitia; Commane, Daniel M.; Rowland, Ian; Gibson, Glenn R.; Kennedy, Orla B.

    2017-01-01

    Background Preload studies are used to investigate the satiating effects of foods and food ingredients. However, the design of preload studies is complex, with many methodological considerations influencing appetite responses. The aim of this pilot investigation was to determine acceptability, and optimise methods, for a future satiety preload study. Specifically, we investigated the effects of altering (i) energy intake at a standardised breakfast (gender-specific or non-gender specific), an...

  12. INVESTIGATING DISTANCE EDUCATION STUDENTS’ STUDY SKILLS

    Directory of Open Access Journals (Sweden)

    Cengiz POYRAZ

    2013-10-01

    Full Text Available Distance education, which is a planned way of teaching in which students and instructors are brought face to face in a classroom environment in several different ways by means of technology, has started to become widespread in many fields today. In distance education, students and instructors reside in different locations. Students can learn at their pace and control their learning path, content and load of what they have learned and evaluate it. However, they should adopt strategies for effective studying in order not to waste their time and efforts. Because study skills, motivation, time management, exam preparation and coping with exam stress have an impact on students’ success. In this context, distance education students’ study skills are foregrounded in today’s widespread use of distance education. In accordance with this, this study aims to investigate some variables which are influential on the dimensions of distance education students’ motivation, time management, exam preparation and coping with exam stress. A personal information form and the Study Skills scale were used for data collection. This study was designed in survey model and SPSS16.0 statistical package program was used for the statistical analyses of the research data. The research findings were discussed in line with the literature and some suggestions were presented for further research and researchers.

  13. Investigating Science Collaboratively: A Case Study of Group Learning

    Science.gov (United States)

    Zinicola, Debra A.

    2009-01-01

    Discussions of one urban middle school group of students who were investigating scientific phenomena were analyzed; this study was conducted to discern if and how peer interaction contributes to learning. Through a social constructivist lens, case study methodology, we examined conceptual change among group members. Data about science talk was…

  14. A Meta-Analysis of Cross Sectional Studies Investigating Language in Maltreated Children

    Science.gov (United States)

    Lum, Jarrad A. G.; Powell, Martine; Timms, Lydia; Snow, Pamela

    2015-01-01

    Purpose: In this review article, meta-analysis was used to summarize research investigating language skills in maltreated children. Method: A systematic search of published studies was undertaken. Studies were included in the meta-analysis if they investigated language skills in groups comprising maltreated and nonmaltreated children. Studies were…

  15. pilot studies to test the feasibility of a birth cohort study investigating ...

    African Journals Online (AJOL)

    1991-04-20

    Apr 20, 1991 ... of a birth cohort study investigating the effects of urbanisation in South Africa. S. FONN, M. DE ... is to determine the biological, environmental, economic and psychological factors that are associated with ... the South African Medical Research Council, Parowvallei,. CP. S. FONN, M.B. B.CH., D.O.H., D.EPL, ...

  16. PENGARUH GROUP INVESTIGATION BERBASIS OUTDOOR STUDY TERHADAP KEMAMPUAN BERPIKIR ANALITIS SISWA

    Directory of Open Access Journals (Sweden)

    Valeriana Rasweda

    2016-02-01

    Full Text Available The purpose of research is to find out the Group Investigation outdoor study-based having an affect on student’s analytichal thinking ability. The type of research is PretestPosttest Control Group Design. The research was conducted at Lawang 1st Public Senior High School Malang Regency with experiment class X-IIS 1 and control class X-IIS 2. The data is an analytichal thinking ability. Data analysis was done by comparing the gain score student’s analytichal thinking ability using SPSS 17.0 for Windows. The results showed that Group Investigation outdoor study-based having an affect on student’s analytichal thinking ability.  Tujuan penelitian ini adalah untuk mengetahui apakah model Group Investigation berbasis outdoor study berpengaruh terhadap kemampuan berpikir analitis siswa. Penelitian ini merupakan jenis penelitian eksperimen semu (quasi experiment yang termasuk penelitian kuantitatif. Rancangan penelitian yang dikembangkan adalah Pretest-Posttest Control Group Design. Penelitian dilaksanakan di SMA Negeri 1 Lawang Kabupaten Malang. Kelas ekperimen ialah kelas X-IIS 1 dan kelas kontrol ialah kelas X-IIS 2. Data yang digunakan dalam penelitian ini adalah kemampuan berpikir analitis. Analisis data dilakukan dengan membandingkan gain score kemampuan berpikir analitis siswa menggunakan bantuan program SPSS 17.0 for Windows. Hasil dari penelitian ini menunjukkan bahwa model Group Investigation berbasis outdoor study berpengaruh terhadap kemampuan berpikir analitis siswa.

  17. A clinical and investigational study of donovanosis

    Directory of Open Access Journals (Sweden)

    Veeranna S

    2003-03-01

    Full Text Available A clinical and investigational study of 25 cases of Donovanosis was undertaken. The incidence was found to be 1.53% of all STD cases and 2.9% of GUD. M:F ratio was 2.12:1. Incidence was more in unmarried people. Fleshy exuberant type was seen in 88% of cases. Two patients (8% had extragenital ulcers. Donovan bodies were found in 88%. Pseudo elephantiasis was seen in 8 patients. Biopsy was done in 8 cases and showed ocanthosis, plasma cell infiltration and pseudo epitheliomatous hyperplasia. One patient developed squamous cell carcinoma of vulva.

  18. Financial ties of principal investigators and randomized controlled trial outcomes: cross sectional study.

    Science.gov (United States)

    Ahn, Rosa; Woodbridge, Alexandra; Abraham, Ann; Saba, Susan; Korenstein, Deborah; Madden, Erin; Boscardin, W John; Keyhani, Salomeh

    2017-01-17

     To examine the association between the presence of individual principal investigators' financial ties to the manufacturer of the study drug and the trial's outcomes after accounting for source of research funding.  Cross sectional study of randomized controlled trials (RCTs).  Studies published in "core clinical" journals, as identified by Medline, between 1 January 2013 and 31 December 2013.  Random sample of RCTs focused on drug efficacy.  Association between financial ties of principal investigators and study outcome.  A total of 190 papers describing 195 studies met inclusion criteria. Financial ties between principal investigators and the pharmaceutical industry were present in 132 (67.7%) studies. Of 397 principal investigators, 231 (58%) had financial ties and 166 (42%) did not. Of all principal investigators, 156 (39%) reported advisor/consultancy payments, 81 (20%) reported speakers' fees, 81 (20%) reported unspecified financial ties, 52 (13%) reported honorariums, 52 (13%) reported employee relationships, 52 (13%) reported travel fees, 41 (10%) reported stock ownership, and 20 (5%) reported having a patent related to the study drug. The prevalence of financial ties of principal investigators was 76% (103/136) among positive studies and 49% (29/59) among negative studies. In unadjusted analyses, the presence of a financial tie was associated with a positive study outcome (odds ratio 3.23, 95% confidence interval 1.7 to 6.1). In the primary multivariate analysis, a financial tie was significantly associated with positive RCT outcome after adjustment for the study funding source (odds ratio 3.57 (1.7 to 7.7). The secondary analysis controlled for additional RCT characteristics such as study phase, sample size, country of first authors, specialty, trial registration, study design, type of analysis, comparator, and outcome measure. These characteristics did not appreciably affect the relation between financial ties and study outcomes (odds ratio 3.37, 1

  19. Unmarried Mother's Knowledge and Attitudes toward Emergency Contraceptive Pills

    Directory of Open Access Journals (Sweden)

    Gyeong Mi Lee

    2013-06-01

    Full Text Available PurposeThis study was conducted to identify relationships among knowledge and attitudes of unmarried mothers toward emergency contraceptive pills.MethodsData were collected through structured questionnaires from 135 unmarried mothers enrolled in 7 single mothers' facilities nationwide. Data were analyzed using the SPSS/WIN 17.0 program for descriptive statistics, t-test, ANOVA, Scheffe-test, and Pearson correlation coefficients.ResultsFor knowledge about emergency contraceptive pills, there were significant differences among who live with her before pregnancy, experience of past pregnancies, state of present pregnancy and preparation in using contraceptives. For attitude toward emergency contraceptive pills, there were significant differences according to age, education level and religion. There were significant positive relationships between knowledge and attitudes toward emergency contraceptive pills.ConclusionThe results of this study suggest that unmarried women should be better informed about emergency contraceptive pills, and reassured about their safety. Efforts are needed to disseminate up-to-date information to experts in sex education including nurses.

  20. Neuroscience Investigations: An Overview of Studies Conducted

    Science.gov (United States)

    Reschke, Millard F.

    1999-01-01

    The neural processes that mediate human spatial orientation and adaptive changes occurring in response to the sensory rearrangement encountered during orbital flight are primarily studied through second and third order responses. In the Extended Duration Orbiter Medical Project (EDOMP) neuroscience investigations, the following were measured: (1) eye movements during acquisition of either static or moving visual targets, (2) postural and locomotor responses provoked by unexpected movement of the support surface, changes in the interaction of visual, proprioceptive, and vestibular information, changes in the major postural muscles via descending pathways, or changes in locomotor pathways, and (3) verbal reports of perceived self-orientation and self-motion which enhance and complement conclusions drawn from the analysis of oculomotor, postural, and locomotor responses. In spaceflight operations, spatial orientation can be defined as situational awareness, where crew member perception of attitude, position, or motion of the spacecraft or other objects in three-dimensional space, including orientation of one's own body, is congruent with actual physical events. Perception of spatial orientation is determined by integrating information from several sensory modalities. This involves higher levels of processing within the central nervous system that control eye movements, locomotion, and stable posture. Spaceflight operational problems occur when responses to the incorrectly perceived spatial orientation are compensatory in nature. Neuroscience investigations were conducted in conjunction with U. S. Space Shuttle flights to evaluate possible changes in the ability of an astronaut to land the Shuttle or effectively perform an emergency post-landing egress following microgravity adaptation during space flights of variable length. While the results of various sensory motor and spatial orientation tests could have an impact on future space flights, our knowledge of

  1. Efficacy of a Radiation Absorbing Shield in Reducing Dose to the Interventionalist During Peripheral Endovascular Procedures: A Single Centre Pilot Study

    International Nuclear Information System (INIS)

    Power, S.; Mirza, M.; Thakorlal, A.; Ganai, B.; Gavagan, L. D.; Given, M. F.; Lee, M. J.

    2015-01-01

    PurposeThis prospective pilot study was undertaken to evaluate the feasibility and effectiveness of using a radiation absorbing shield to reduce operator dose from scatter during lower limb endovascular procedures.Materials and MethodsA commercially available bismuth shield system (RADPAD) was used. Sixty consecutive patients undergoing lower limb angioplasty were included. Thirty procedures were performed without the RADPAD (control group) and thirty with the RADPAD (study group). Two separate methods were used to measure dose to a single operator. Thermoluminescent dosimeter (TLD) badges were used to measure hand, eye, and unshielded body dose. A direct dosimeter with digital readout was also used to measure eye and unshielded body dose. To allow for variation between control and study groups, dose per unit time was calculated.ResultsTLD results demonstrated a significant reduction in median body dose per unit time for the study group compared with controls (p = 0.001), corresponding to a mean dose reduction rate of 65 %. Median eye and hand dose per unit time were also reduced in the study group compared with control group, however, this was not statistically significant (p = 0.081 for eye, p = 0.628 for hand). Direct dosimeter readings also showed statistically significant reduction in median unshielded body dose rate for the study group compared with controls (p = 0.037). Eye dose rate was reduced for the study group but this was not statistically significant (p = 0.142).ConclusionInitial results are encouraging. Use of the shield resulted in a statistically significant reduction in unshielded dose to the operator’s body. Measured dose to the eye and hand of operator were also reduced but did not reach statistical significance in this pilot study

  2. Efficacy of a Radiation Absorbing Shield in Reducing Dose to the Interventionalist During Peripheral Endovascular Procedures: A Single Centre Pilot Study

    Energy Technology Data Exchange (ETDEWEB)

    Power, S.; Mirza, M.; Thakorlal, A.; Ganai, B.; Gavagan, L. D.; Given, M. F.; Lee, M. J., E-mail: mlee@rcsi.ie [Beaumont Hospital, Imaging and Interventional Radiology Department (Ireland)

    2015-06-15

    PurposeThis prospective pilot study was undertaken to evaluate the feasibility and effectiveness of using a radiation absorbing shield to reduce operator dose from scatter during lower limb endovascular procedures.Materials and MethodsA commercially available bismuth shield system (RADPAD) was used. Sixty consecutive patients undergoing lower limb angioplasty were included. Thirty procedures were performed without the RADPAD (control group) and thirty with the RADPAD (study group). Two separate methods were used to measure dose to a single operator. Thermoluminescent dosimeter (TLD) badges were used to measure hand, eye, and unshielded body dose. A direct dosimeter with digital readout was also used to measure eye and unshielded body dose. To allow for variation between control and study groups, dose per unit time was calculated.ResultsTLD results demonstrated a significant reduction in median body dose per unit time for the study group compared with controls (p = 0.001), corresponding to a mean dose reduction rate of 65 %. Median eye and hand dose per unit time were also reduced in the study group compared with control group, however, this was not statistically significant (p = 0.081 for eye, p = 0.628 for hand). Direct dosimeter readings also showed statistically significant reduction in median unshielded body dose rate for the study group compared with controls (p = 0.037). Eye dose rate was reduced for the study group but this was not statistically significant (p = 0.142).ConclusionInitial results are encouraging. Use of the shield resulted in a statistically significant reduction in unshielded dose to the operator’s body. Measured dose to the eye and hand of operator were also reduced but did not reach statistical significance in this pilot study.

  3. ECOLITERACY SISWA SD DALAM KEGIATAN PENGELOLAAN SAMPAH MELALUI GROUP INVESTIGATION BERBASIS OUTDOOR STUDY

    Directory of Open Access Journals (Sweden)

    Fanny Karlina

    2017-07-01

    Full Text Available The aim of this research is to improve the student’s ecoliteracy in waste managing activities on social studies trough group investigation based outdoor study. This research is Classroom Action Research toward fourth graders have been held on two cycles. The conclusion of this research is student’s ecoliteracy cognitive aspect increases is 20%, application aspect increases is 49,6%, and attitude aspect increases is 19,4% after the two cycle action with group investigation based outdoor study. Penelitian ini bertujuan mendeskripsikan peningkatan ecoliteracy siswa dalam kegiatan pengelolaan sampah dalam pembelajaran IPS melalui group investigation berbasis outdoor study. Penelitian ini menerapkan jenis Penelitian Tindakan Kelas (PTK terhadap siswa kelas IV SD yang dilaksanakan dalam dua siklus. Hasil penelitian menyimpulkan adanya peningkatan ecoliteracy siswa dari aspek pengetahuan sebesar 20%, aspek aplikasi sebesar 49,6%, dan aspek sikap sebesar 19,4% setelah mengikuti dua siklus pembelajaran dengan group investigation berbasis outdoor study.

  4. Incidence trends and associated factors of diabetes mellitus in Korean children and adolescents: a retrospective cohort study in Busan and Gyeongnam

    Directory of Open Access Journals (Sweden)

    Jung Hyun Lee

    2015-12-01

    Full Text Available PurposeThis study investigated the incidence trends and associated factors of type 1 (T1DM and type 2 diabetes mellitus (T2DM in children and adolescents under 15 years of age in Busan and Gyeongnam, Korea from 2001 to 2010.MethodsMedical records of newly diagnosed diabetes patients (n=328; 160 males, 168 females were collected in questionnaire form from 5 tertiary and 42 general hospitals in Busan and Gyeongnam.ResultsThe average crude incidence rate of T1DM and T2DM was 2.01/100,000 (95% confidence interval [CI], 1.76-2.28 and 0.75/100,000 (95% CI, 0.60-0.92, respectively. The incidence rate ratio (IRR of T1DM was 1.31 (95% CI, 1.01-1.69, and that of T2DM was 1.97 (95% CI, 1.25-3.11 in the latter half-decade (2006 to 2010 compared to the early half-decade (2001 to 2005. There were gradually increasing incidence trends in both T1DM and T2DM over the 10-year period (P for trend: T1DM, 0.0009; T2DM, <0.0001. Age-specific IRR was highest in the 10- to 14-year-old group, regardless of diabetes type. In particular, a rapid increase in incidence of T2DM occurred in the 10- to 14-year-old group. IRR for females was 1.07 (95% CI, 0.83-1.38 for T1DM and 1.56 (95% CI, 1.01-2.41 for T2DM. IRR for Busan (urban was 1.41 (95% CI, 1.09-1.83 for T1DM and 1.49 (95% CI, 0.96-2.30 for T2DM.ConclusionT1DM and T2DM incidence both increased over time in youth under age 15 living in Busan and Gyeongnam; in particular, the incidence of T2DM in adolescents increased more rapidly.

  5. A forensic perspective of the AFL investigation into peptides: an antidoping investigation case study.

    Science.gov (United States)

    Harcourt, Peter Rex; Marclay, Francois; Clothier, Brett

    2014-05-01

    The World Anti-Doping Agency (WADA) is introducing enhancements to doping investigations in its 2015 Code, which include improved sharing of information between antidoping organisations (including sporting bodies) and enhanced accountability of athlete support staff. These additions will improve the control of links between sports doping and organised crime. In February 2013 the Australian Crime Commission released a report that linked several professional sporting codes, professional athletes with links to organised crime, performance enhancing drugs and illicit substances. Following this report the Australian Football League (AFL) partnered the Australian national antidoping organisation to investigate peptide use in Australian football. This review compared the model proposed by Marclay, a hypothetical model for anti-doping investigations that proposed a forensic intelligence and analysis approach, to use the forensic capabilities of the AFL investigation to test the model's relevance to an actual case. The investigation uncovered the use of peptides used to enhance athlete performance. The AFL investigation found a high risk of doping where athlete support staff existed in teams with weak corporate governance controls. A further finding included the need for the investigation to provide a timely response in professional team sports that were sensitive to the competition timing. In the case of the AFL the team was sanctioned prior to the finals as an interim outcome for allowing the risk of use of performance-enhancing substances. Doping violation charges are still being considered. Antidoping strategies should include the investigation of corporate officers in team doping circumstances, the mandatory recording of all athlete substance use during competition and training phases, the wider sharing of forensic intelligence with non-sporting bodies particularly law enforcement and collaboration between antidoping and sporting organisations in doping investigations

  6. Investigation, study and practice of optoelectronic MOOCs

    Science.gov (United States)

    Shi, Jianhua; Liu, Wei; Lei, Bing; Yao, Tianfu; Fu, Sihua

    2017-08-01

    MOOC(Massive Open Online Course) is a new teaching model that has been springing up since 2012. The typical characters are short teaching video, massive learners, flexible place and time to study, etc. Although MOOC is very popular now, opto-electronic MOOCs are not much enough to meet the need of online learners. In this paper, the phylogeny, the current situation and the characters of MOOC were described, the most famous MOOCs' websites, such as Udacity, Coursera, edX, Chinese College MOOC, xuetangx, were introduced, the opto-electronic MOOCs come from these famous MOOCs' website were investigated extensively and studied deeply, the "Application of Opto-electronic Technology MOOC" which was established by our group is introduced, and some conclusions are obtained. These conclusions can give some suggestions to the online learners who are interested in opto-electronic and the teachers who are teaching the opto-electronic curriculums. The preparation of "Opto-electronic Technology MOOC" is described in short.

  7. A case study on the investigation of reasoning skills in geometry ...

    African Journals Online (AJOL)

    The aim of this study is to evaluate the reasoning skills in geometry-related subjects of six 8th Grade students. The study data were obtained at the end of the 2011-2012 spring period in a public elementary school. The study uses a case study with qualitative research techniques to investigate how students use reasoning ...

  8. Fusion Guidance in Endovascular Peripheral Artery Interventions: A Feasibility Study

    Energy Technology Data Exchange (ETDEWEB)

    Sailer, Anna M., E-mail: anni.sailer@mumc.nl; Haan, Michiel W. de, E-mail: m.de.haan@mumc.nl; Graaf, Rick de, E-mail: r.de.graaf@mumc.nl; Zwam, Willem H. van, E-mail: w.van.zwam@mumc.nl [Maastricht University Medical Center, Department of Radiology (Netherlands); Schurink, Geert Willem H., E-mail: gwh.schurink@mumc.nl [Maastricht University Medical Center, Department of Surgery (Netherlands); Nelemans, Patricia J., E-mail: patty.nelemans@maastrichtuniversity.nl [Maastricht University Medical Centre, Department of Epidemiology (Netherlands); Wildberger, Joachim E., E-mail: j.wildberger@mumc.nl; Das, Marco, E-mail: m.das@mumc.nl [Maastricht University Medical Center, Department of Radiology (Netherlands)

    2015-04-15

    PurposeThis study was designed to evaluate the feasibility of endovascular guidance by means of live fluoroscopy fusion with magnetic resonance angiography (MRA) and computed tomography angiography (CTA).MethodsFusion guidance was evaluated in 20 endovascular peripheral artery interventions in 17 patients. Fifteen patients had received preinterventional diagnostic MRA and two patients had undergone CTA. Time for fluoroscopy with MRA/CTA coregistration was recorded. Feasibility of fusion guidance was evaluated according to the following criteria: for every procedure the executing interventional radiologists recorded whether 3D road-mapping provided added value (yes vs. no) and whether PTA and/or stenting could be performed relying on the fusion road-map without need for diagnostic contrast-enhanced angiogram series (CEAS) (yes vs. no). Precision of the fusion road-map was evaluated by recording maximum differences between the position of the vasculature on the virtual CTA/MRA images and conventional angiography.ResultsAverage time needed for image coregistration was 5 ± 2 min. Three-dimensional road-map added value was experienced in 15 procedures in 12 patients. In half of the patients (8/17), intervention was performed relying on the fusion road-map only, without diagnostic CEAS. In two patients, MRA roadmap showed a false-positive lesion. Excluding three patients with inordinate movements, mean difference in position of vasculature on angiography and MRA/CTA road-map was 1.86 ± 0.95 mm, implying that approximately 95 % of differences were between 0 and 3.72 mm (2 ± 1.96 standard deviation).ConclusionsFluoroscopy with MRA/CTA fusion guidance for peripheral artery interventions is feasible. By reducing the number of CEAS, this technology may contribute to enhance procedural safety.

  9. Fusion Guidance in Endovascular Peripheral Artery Interventions: A Feasibility Study

    International Nuclear Information System (INIS)

    Sailer, Anna M.; Haan, Michiel W. de; Graaf, Rick de; Zwam, Willem H. van; Schurink, Geert Willem H.; Nelemans, Patricia J.; Wildberger, Joachim E.; Das, Marco

    2015-01-01

    PurposeThis study was designed to evaluate the feasibility of endovascular guidance by means of live fluoroscopy fusion with magnetic resonance angiography (MRA) and computed tomography angiography (CTA).MethodsFusion guidance was evaluated in 20 endovascular peripheral artery interventions in 17 patients. Fifteen patients had received preinterventional diagnostic MRA and two patients had undergone CTA. Time for fluoroscopy with MRA/CTA coregistration was recorded. Feasibility of fusion guidance was evaluated according to the following criteria: for every procedure the executing interventional radiologists recorded whether 3D road-mapping provided added value (yes vs. no) and whether PTA and/or stenting could be performed relying on the fusion road-map without need for diagnostic contrast-enhanced angiogram series (CEAS) (yes vs. no). Precision of the fusion road-map was evaluated by recording maximum differences between the position of the vasculature on the virtual CTA/MRA images and conventional angiography.ResultsAverage time needed for image coregistration was 5 ± 2 min. Three-dimensional road-map added value was experienced in 15 procedures in 12 patients. In half of the patients (8/17), intervention was performed relying on the fusion road-map only, without diagnostic CEAS. In two patients, MRA roadmap showed a false-positive lesion. Excluding three patients with inordinate movements, mean difference in position of vasculature on angiography and MRA/CTA road-map was 1.86 ± 0.95 mm, implying that approximately 95 % of differences were between 0 and 3.72 mm (2 ± 1.96 standard deviation).ConclusionsFluoroscopy with MRA/CTA fusion guidance for peripheral artery interventions is feasible. By reducing the number of CEAS, this technology may contribute to enhance procedural safety

  10. Chinese college students' understanding of Internet ethical issues: A survey of awareness and attitude

    Institute of Scientific and Technical Information of China (English)

    Yuelin LI; Ying LI; Ang LI

    2014-01-01

    Purpose:This study examines Chinese college students' awareness of ethical issues surrounding the use of information resources and the Internet and their attitude to these issues.Design/methodology/approach:A survey was conducted.Two hundred questionnaires were distributed to students of 9 universities at different levels in Tianjin,China;171 were returned.Descriptive statistics were performed to analyze the data.Findings:The results indicate that Chinese college students usually ignored the negative influence of fake or pornographic or other indecent information,invasion of privacy and theft of confidential information,and violation of intellectual property rights.Although they could distinguish to some extent between ethical and unethical behavior,they were not concerned about others' unethical behavior on the Web.The study also indicates that gender,age,academic major and expertise in using computers were related to the students' awareness of ethical issues relating to the use of the Internet and their attitude to these issues.Research limitations:The sample is limited to the universities in Tianjin.A larger sample,which includes colleges and universities in the western or other developing areas in China,is needed to further validate our findings.Practical implications:The study helps educators and academic librarians better understand Chinese college students' awareness of and attitude to ethical issues surrounding the use of the Internet.It thus could assist them in the improvement of information ethics education for college students.Originality/value:This study was one of the first empirical studies to investigate the factors influencing Chinese college students' awareness of and attitude to Internet ethical issues.

  11. Investigating Prospective Social Studies Teachers? Perceptions of European Union through Metaphor Analysis

    Science.gov (United States)

    Akgün, Ismail Hakan

    2017-01-01

    The purpose of this study is to investigate metaphors developed by social studies teacher candidates about the European Union. 185 second, third and fourth year social studies teacher candidates participated in the study. This study was designed as a phenomenological study and mataphor analysis was conducted. At the end of the study, the students…

  12. Accident Investigation on a Large Construction Project: An Ethnographic Case Study

    OpenAIRE

    Oswald, David; Smith, Simon; Sherratt, Fred

    2015-01-01

    Unsafe acts are believed to account for approximately 80 to 90 percent of accidents. This paper will investigate this issue through exploring the reasoning behind the unsafe acts that resulted in a minor accident on a large construction project (+$1B) in the UK. The study described here, part of a wider PhD project, was undertaken using an ethnographic approach. Participant observation enabled the researcher to be involved in the whole accident investigation process including witness statemen...

  13. Digital Forensic Investigation Models, an Evolution study

    Directory of Open Access Journals (Sweden)

    Khuram Mushtaque

    2015-10-01

    Full Text Available In business today, one of the most important segments that enable any business to get competitive advantage over others is appropriate, effective adaptation of Information Technology into business and then managing and governing it on their will. To govern IT organizations need to identify value of acquiring services of forensic firms to compete cyber criminals. Digital forensic firms follow different mechanisms to perform investigation. Time by time forensic firms are facilitated with different models for investigation containing phases for different purposes of the entire process. Along with forensic firms, enterprises also need to build a secure and supportive platform to make successful investigation process possible. We have underlined different elements of organizations in Pakistan; need to be addressed to provide support to forensic firms.

  14. Study of Womens Health Across the Nation (SWAN) Data: Investigator Access

    Data.gov (United States)

    U.S. Department of Health & Human Services — The SWAN Coordinating Center provides SWAN data access to SWAN Investigators through the study website. The SWAN website provides access to longitudinal data...

  15. Phase I/II Multi-Institutional Study of Percutaneous Radiofrequency Ablation for Painful Osteoid Osteoma (JIVROSG-0704)

    Energy Technology Data Exchange (ETDEWEB)

    Miyazaki, Masaya, E-mail: mmiyazak@gunma-u.ac.jp [Gunma University Hospital, Department of Interventional Radiology and Clinical Ultrasound Center (Japan); Arai, Yasuaki [National Center Hospital, Division of Diagnostic Radiology (Japan); Myoui, Akira [Osaka University Hospital, Medical Center for Translational Research (Japan); Gobara, Hideo [Okayama University Medical School, Department of Radiology (Japan); Sone, Miyuki [National Center Hospital, Division of Diagnostic Radiology (Japan); Rosenthal, Daniel I. [Harvard Medical School, Department of Radiology, Massachusetts General Hospital (United States); Tsushima, Yoshito [Gunma University Hospital, Department of Interventional Radiology and Clinical Ultrasound Center (Japan); Kanazawa, Susumu [Okayama University Medical School, Department of Radiology (Japan); Ehara, Shigeru [Iwate Medical University School of Medicine, Department of Radiology (Japan); Endo, Keigo [Gunma University Hospital, Department of Interventional Radiology and Clinical Ultrasound Center (Japan)

    2016-10-15

    PurposeThis multicenter prospective study was conducted to evaluate the safety and efficacy of percutaneous radiofrequency ablation (RFA) for painful osteoid osteoma (OO).Materials and MethodsPatients with OO (femur: n = 17, tibia: n = 2, humerus: n = 1, rib: n = 1) were enrolled and treated with RFA. In phase I, nine patients were evaluated for safety. In phase II, 12 patients were accrued, and an intent-to-treat analysis was performed on all patients. The primary endpoint was to evaluate the treatment safety. The secondary endpoint was to evaluate the efficacy for pain relief by the visual analogue scale (VAS) at 4 weeks after RFA. Treatment efficacy was classified as significantly effective (SE) when VAS score decreased by ≥5 or score was <2, moderately effective when VAS score decreased by <5–≥2 and score was ≥2, and not effective (NE) when VAS score decreased by <2 or score was increased. Cases where the need for analgesics increased after treatment were also NE.ResultsRFA procedures were completed in all patients. Minor adverse effects (AEs) were observed as 4.8–14.3 % in 12 patients, and no major AEs were observed. Mean VAS score was 7.1 before treatment, 1.6 at 1 week, 0.3 at 4 weeks, and 0.2 at 3 months. All procedures were classified as SE. Pain recurrence was not noted in any patient during follow-up (mean: 15.1 months).ConclusionRFA is a safe, highly effective, and fast-acting treatment for painful extraspinal OO. Future studies with a greater number of patients are needed.

  16. Investigating employee resistance to Lean transformation: UK case study.

    OpenAIRE

    Bruce, J.; Scott, Philip; Roberts, Martyn

    2011-01-01

    Lean is a business process transformation approach that eliminates ‘wastes’ – activities that generate no value for the customer. Lean originated from the production line but is widely implemented in the service sector. This study investigates human and social factors in a Lean transformation in a ‘knowledge worker’ environment. We identify a paradox: a successful Lean programme in the service sector develops staff who are educated and empowered and thus potential opponents to future business...

  17. The SimpleMix study with biphasic insulin aspart 30: a randomized controlled trial investigating patient-driven titration versus investigator-driven titration.

    Science.gov (United States)

    Gao, Yan; Luquez, Cecilia; Lynggaard, Helle; Andersen, Henning; Saboo, Banshi

    2014-12-01

    The study aimed to confirm the efficacy, through non-inferiority, of patient-driven versus investigator-driven titration of biphasic insulin aspart 30 (BIAsp 30) in terms of glycemic control assessed by HbA1c change. SimpleMix was a 20 week, open-label, randomized, two-armed, parallel-group, multicenter study in five countries (Argentina, China, India, Poland, and the UK). Patients with type 2 diabetes were randomized into either patient-driven or investigator-driven BIAsp 30 titration groups. Non-inferiority of patient-driven vs. investigator-driven titration based on change in HbA1c from baseline to week 20 could not be demonstrated. Mean (SE) estimated change from baseline to week 20 was -0.72 (0.08)% in the patient-driven group and -0.97 (0.08)% in the investigator-driven group; estimated difference 0.25% (95% CI: 0.04; 0.46). Estimated mean change (SE) in fasting plasma glucose from baseline to week 20 was similar between groups: -0.94 (0.21) mmol/L for patient-driven and -1.07 (0.22) mmol/L for investigator-driven (difference non-significant). Both treatment arms were well tolerated, and hypoglycemic episode rates were similar between groups, with a rate ratio of 0.77 (95% CI: 0.54; 1.09; p = 0.143) for all hypoglycemic episodes and 0.78 (95% CI: 0.42; 1.43; p = 0.417) for nocturnal hypoglycemic episodes. Non-inferiority of patient-driven versus investigator-driven titration with regard to change from baseline to end-of-treatment HbA1c could not be confirmed. It is possible that a clinic visit 12 weeks after intensification of treatment with BIAsp 30 in patients with type 2 diabetes inadequately treated with basal insulin may benefit patient-driven titration of BIAsp 30. A limitation of the study was the relatively small number of patients recruited in each country, which does not allow country-specific analyses to be performed. Overall, treatment with BIAsp 30 was well tolerated in both treatment groups.

  18. Clinical, Laboratorial, and Urodynamic Findings of Prostatic Artery Embolization for the Treatment of Urinary Retention Related to Benign Prostatic Hyperplasia. A Prospective Single-Center Pilot Study

    International Nuclear Information System (INIS)

    Antunes, Alberto A.; Carnevale, Francisco C.; Motta Leal Filho, Joaquim M. da; Yoshinaga, Eduardo M.; Cerri, Luciana M. O.; Baroni, Ronaldo H.; Marcelino, Antonio S. Z.; Cerri, Giovanni G.; Srougi, Miguel

    2013-01-01

    PurposeThis study was designed to describe the clinical, laboratorial, and urodynamic findings of prostatic artery embolization (PAE) in patients with urinary retention due to benign prostatic hyperplasia (BPH).MethodsA prospective study of 11 patients with urinary retention due to BPH was conducted. Patients underwent physical examination, prostate specific antigen (PSA) measurement, transrectal ultrasound, and magnetic resonance imaging. International prostate symptom score (IPSS), quality of life (QoL), and urodynamic testing were used to assess the outcome before and after 1 year.ResultsClinical success was 91 % (10/11 patients) with a mean follow-up of 22.3 months (range, 12–41 months). At the first year follow-up, the mean IPSS score was 2.8 points (p = 0.04), mean QoL was 0.4 points (p = 0.001), mean PSA decreased from 10.1 to 4.3 ng/mL (p = 0.003), maximum urinary flow (Qmax) improved from 4.2 to 10.8 mL/sec (p = 0.009), and detrusor pressure (Pdet) decreased from 85.7 to 51.5 cm H 2 O (p = 0.007). Before PAE, Bladder Outlet Obstruction Index (BOOI) showed values >40 in 100 % of patients. After PAE, 30 % of patients were >40 (obstructed), 40 % were between 20 and 40 (undetermined), and 30 % were <20 (unobstructed). Patients with a BOOI <20 had higher PSA values at 1-day after PAE.ConclusionsClinical and urodynamic parameters improved significantly after PAE in patients with acute urinary retention due to BPH. Total PSA at day 1 after PAE was higher in patients with unobstructed values in pressure flow studies

  19. Clinical, Laboratorial, and Urodynamic Findings of Prostatic Artery Embolization for the Treatment of Urinary Retention Related to Benign Prostatic Hyperplasia. A Prospective Single-Center Pilot Study

    Energy Technology Data Exchange (ETDEWEB)

    Antunes, Alberto A. [University of Sao Paulo Medical School, Division of Urology (Brazil); Carnevale, Francisco C., E-mail: fcarnevale@uol.com.br; Motta Leal Filho, Joaquim M. da [University of Sao Paulo Medical School, Interventional Radiology Unit (Brazil); Yoshinaga, Eduardo M. [University of Sao Paulo Medical School, Division of Urology (Brazil); Cerri, Luciana M. O. [University of Sao Paulo Medical School, Ultrasound Unit (Brazil); Baroni, Ronaldo H. [University of Sao Paulo Medical School, Magnetic Resonance Unit (Brazil); Marcelino, Antonio S. Z. [University of Sao Paulo Medical School, Ultrasound Unit (Brazil); Cerri, Giovanni G. [University of Sao Paulo Medical School, Radiology Department (Brazil); Srougi, Miguel [University of Sao Paulo Medical School, Division of Urology (Brazil)

    2013-08-01

    PurposeThis study was designed to describe the clinical, laboratorial, and urodynamic findings of prostatic artery embolization (PAE) in patients with urinary retention due to benign prostatic hyperplasia (BPH).MethodsA prospective study of 11 patients with urinary retention due to BPH was conducted. Patients underwent physical examination, prostate specific antigen (PSA) measurement, transrectal ultrasound, and magnetic resonance imaging. International prostate symptom score (IPSS), quality of life (QoL), and urodynamic testing were used to assess the outcome before and after 1 year.ResultsClinical success was 91 % (10/11 patients) with a mean follow-up of 22.3 months (range, 12-41 months). At the first year follow-up, the mean IPSS score was 2.8 points (p = 0.04), mean QoL was 0.4 points (p = 0.001), mean PSA decreased from 10.1 to 4.3 ng/mL (p = 0.003), maximum urinary flow (Qmax) improved from 4.2 to 10.8 mL/sec (p = 0.009), and detrusor pressure (Pdet) decreased from 85.7 to 51.5 cm H{sub 2}O (p = 0.007). Before PAE, Bladder Outlet Obstruction Index (BOOI) showed values >40 in 100 % of patients. After PAE, 30 % of patients were >40 (obstructed), 40 % were between 20 and 40 (undetermined), and 30 % were <20 (unobstructed). Patients with a BOOI <20 had higher PSA values at 1-day after PAE.ConclusionsClinical and urodynamic parameters improved significantly after PAE in patients with acute urinary retention due to BPH. Total PSA at day 1 after PAE was higher in patients with unobstructed values in pressure flow studies.

  20. Study on the Geological Structure around KURT Using a Deep Borehole Investigation

    International Nuclear Information System (INIS)

    Park, Kyung Woo; Kim, Kyung Su; Koh, Yong Kwon; Choi, Jong Won

    2010-01-01

    To characterize geological features in study area for high-level radioactive waste disposal research, KAERI (Korea Atomic Energy Research Institute) has been performing the several geological investigations such as geophysical surveys and borehole drilling since 1997. Especially, the KURT (KAERI Underground Research Tunnel) constructed to understand the deep geological environments in 2006. Recently, the deep borehole of 500 m depths was drilled to confirm and validate the geological model at the left research module of the KURT. The objective of this research was to identify the geological structures around KURT using the data obtained from the deep borehole investigation. To achieve the purpose, several geological investigations such as geophysical and borehole fracture surveys were carried out simultaneously. As a result, 7 fracture zones were identified in deep borehole located in the KURT. As one of important parts of site characterization on KURT area, the results will be used to revise the geological model of the study area

  1. An Investigation of the Internal Structure of the Biggs Study Process Questionnaire.

    Science.gov (United States)

    Watkins, David; Hattie, John

    1980-01-01

    Results of an Australian study of the Biggs Study Process Questionnaire (SPQ) are presented. The purposes of the research were to: (1) re-examine the SPQ's internal consistency; (2) explore dimensionality of the SPQ scales; and (3) investigate validity of Bigg's model of the study process complex through factor analysis. (Author/GK)

  2. Promoting Prosocial Beliefs And Behavior Toward People With Disabilities In Nepal Through A Children’s Entertainment-Education Program

    Directory of Open Access Journals (Sweden)

    William J Brown

    2011-10-01

    Full Text Available PurposeThis quasi-experimental field study examines the prosocial influences of a children's entertainment-education television programme, Khushi Ko Sansar, on children’s beliefs and intended behaviour towards people with disabilities in Nepal.MethodPre-test and post-test survey data were gathered from 357 Nepali children from nine communities that took part in the study. The children were shown two television episodes in which the star of the programmes, a dog named Khush, befriends and visits people with disabilities.ResultsPost-test results show that children developed strong identification with Khush and adopted his prosocial beliefs and behaviour towards people with disabilities.ConclusionsThe authors conclude that the entertainment-education television programme, Khushi Ko Sansar, provided a positive role model for children who encounter people with disabilities. Implications of these findings suggest that entertainment-education media can improve the treatment of people with disabilities and can promote beneficial health beliefs and practices.Key words: Children’s television, entertainment-education, Nepal, people with disabilities, role modelsdoi 10.5463/DCID.v22i2.33 

  3. Remedidal investigation and feasibility study report for the Environmental Restoration Disposal Facility

    Energy Technology Data Exchange (ETDEWEB)

    Roeck, F.V.

    1994-06-01

    The purpose of the remedial investigation (RI) is to collect data necessary to adequately characterize the site for the purpose of developing and evaluating effective remedial alternatives. To characterize the site, the lead agency shall, as appropriate, conduct field investigations, including treatability studies, and conduct a baseline risk assessment. The RI provides information to assess the risks to human health and the environment and to support the development, evaluation, and selection of appropriate response alternatives. The primary objective of the feasibility study (FS) is to ensure that appropriate remedial alternatives are developed and evaluated such that relevant information concerning the remedial action options can be presented to a decision-maker and an appropriate remedy selected. The lead agency may develop a feasibility study to address a specific site problem or the entire site. The development and evaluation of alternatives shall reflect the scope and complexity of the remedial action under consideration and the site problems being addressed. Development of alternatives shall be fully integrated with the site characterization activities of the remedial investigation described in paragraph (d) of this section. The lead agency shall include an alternatives screening step, when needed, to select a reasonable number of alternatives for detailed analysis.

  4. Remedidal investigation and feasibility study report for the Environmental Restoration Disposal Facility

    International Nuclear Information System (INIS)

    Roeck, F.V.

    1994-06-01

    The purpose of the remedial investigation (RI) is to collect data necessary to adequately characterize the site for the purpose of developing and evaluating effective remedial alternatives. To characterize the site, the lead agency shall, as appropriate, conduct field investigations, including treatability studies, and conduct a baseline risk assessment. The RI provides information to assess the risks to human health and the environment and to support the development, evaluation, and selection of appropriate response alternatives. The primary objective of the feasibility study (FS) is to ensure that appropriate remedial alternatives are developed and evaluated such that relevant information concerning the remedial action options can be presented to a decision-maker and an appropriate remedy selected. The lead agency may develop a feasibility study to address a specific site problem or the entire site. The development and evaluation of alternatives shall reflect the scope and complexity of the remedial action under consideration and the site problems being addressed. Development of alternatives shall be fully integrated with the site characterization activities of the remedial investigation described in paragraph (d) of this section. The lead agency shall include an alternatives screening step, when needed, to select a reasonable number of alternatives for detailed analysis

  5. Investigation of fatigue by Australian general practice registrars: a cross-sectional study.

    Science.gov (United States)

    Morgan, Simon; Henderson, Kim M; Tapley, Amanda; Thomson, Allison; Wilson, Jessica; Scott, John; Spike, Neil A; McArthur, Lawrie; van Driel, Mieke L; Magin, Parker J

    2015-06-01

    Fatigue is the most common undifferentiated problem presenting in general practice. Previous studies have shown that this presentation leads to multiple investigations. There is no published literature describing the management of patients with fatigue by general practice (GP) registrars. To document the investigation-ordering behaviour of GP registrars in managing patients with a new diagnosis of unexplained fatigue. This was a cross-sectional analysis of data from Registrar Clinical Encounters in Training (ReCEnT), an ongoing cohort study of GP registrars' consultations. We established the prevalence of new diagnoses of unexplained fatigue and associations with that diagnosis, the rate of test ordering and the number and types of investigations ordered. 644 registrars contributed data from 68 986 encounters. In 0.78% of patient encounters, a new diagnosis of unexplained fatigue was made. Pathology was ordered in 78.4% of these problems (versus 18.1% in non-fatigue problems), at a rate of 488 tests per 100 new fatigue problems. Our study suggests that unexplained fatigue elicits a non-rational approach to test ordering by registrars. These findings contribute to the understanding of GP registrar management of fatigue, and undifferentiated presentations more broadly, and suggest educational approaches to improve practice, including dealing with uncertainty.

  6. Political skill construct and criterion-related validation: A two-study investigation

    DEFF Research Database (Denmark)

    Ferris, G.R.; Blickle, G.; Schneider, P.B.

    2008-01-01

    made to also identify a single, higher-order factor solution through second-order factor analysis. The present research aims to expand on prior work and report on a two-study investigation of both the construct validity and antecedents and consequences of the political skill construct. Design/methodology...

  7. Investigative study of the underground excavations for a nuclear waste repository in tuff: Nevada Nuclear Waste Storage Investigations Project

    International Nuclear Information System (INIS)

    St John, C.M.

    1987-07-01

    Numerical studies were conducted on the behavior of a tuff rock mass within which emplacement drifts for a nuclear waste repository are excavated. The first study evaluated the effects of rockbolting and excavation-induced damage on the behavior of the rock mass round typical drifts. The second study provided a simple means of assessing the significance of drift shape, drift size, and in-situ state of stress on the deformation and stress in the vicinity of drifts for vertical and horizontal emplacement of waste. Neither study considered the effect of heating of the rock mass after emplacement of the waste so the conclusions pertain only to the conditions immediately after excavation of the underground openings. The results of analyses of the rockbolted excavations indicated that rockbolts do not have a significant influence on the states of deformation or stress within the rock mass, and that the rockbolts are subjected to acceptable levels of stress even if installed as close to the face of the excavation as possible. Accordingly, rockbolts were not considered in the study of drift shape, drift size, and the in-situ state of stress. That study indicated that stable openings of the dimensions investigated can be constructed within a tuff rock mass with the properties assumed. Of the parameters investigated, the in-situ state of stress appeared to be most important. Potentially adverse conditions were predicted if the in-situ horizontal stress is very low, but current indications are that it lies within a range which is consistent with good conditions and a stable roof. 28 refs., 49 figs., 11 tabs

  8. Pilot Study An Investigating Proficiency Learners Attitudes Towards English Language Learning

    Directory of Open Access Journals (Sweden)

    Dr. Ozge Razy

    2015-08-01

    Full Text Available This study attempted to investigate foreign students feeling and behaviour towards learning English and different other languages. The study found out that there is any significant difference in the students aspects attitudes positive and negative towards learning English language inside and outside the school based on their response to 25 items. A total of participants were 18 took a questionnaire as an instrument to qualify their attitudes. The participants showed positive attitudes in the high level towards foreign languages such as English. The study presented recommendation to improve other languages in the future as English.

  9. Investigation on mechanical properties of basalt composite fabrics (experiment study)

    Science.gov (United States)

    Talebi Mazraehshahi, H.; Zamani, H.

    2010-06-01

    To fully appreciate the role and application of composite materials to structures, correct understanding of mechanical behaviors required for selection of optimum material. Fabric reinforced composites are composed of a matrix that is reinforced with pliable fabric, glass fabric is most popular reinforcement for different application specially in aircraft structure, although other fabric material are also used. At this study new fabric material called basalt with epoxy resin introduced and mechanical behaviors of this material investigated from view point of testing. For this study two type of fabric with different thickness used. Comparison between this composite reinforcement with popular reinforcement as carbon, glass, kevlar performed. To determine mechanical properties of epoxy based basalt fabric following test procedure performed : 1). Tensile testing according to ASTM D3039 in 0° and 90° direction to find ultimate strength in tension and shear, modulus of elasticity, elangation and ultimate strain. 2). Compression testing according to EN 2850 ultimate compression strength and maximum deformation under compression loading. 3). Shear testing according to ASTM D3518-94 to find in plane shear response of polymer matrix composites materials. 4). Predict flexural properties of sandwich construction which manufactured from basalt facing with PVC foam core according to ASTM C393-94. Material strength properties must be based on enough tests of material to meet the test procedure specifications [1]. For this reason six specimens were manufactured for testing and the tests were performed on them using an INSTRON machine model 5582. In the study, the effect of percent of resin in basalt reinforced composite was investigated. Also the weights of the ballast based composites with different percent of resin were measured with conventional composites. As the weight is an important parameter in aerospace industry when the designer wants to replace one material with

  10. Cone-Beam Computed Tomography (CBCT) Hepatic Arteriography in Chemoembolization for Hepatocellular Carcinoma: Performance Depicting Tumors and Tumor Feeders

    Energy Technology Data Exchange (ETDEWEB)

    Lee, In Joon [National Cancer Center, Department of Radiology (Korea, Republic of); Chung, Jin Wook, E-mail: chungjw@snu.ac.kr; Yin, Yong Hu; Kim, Hyo-Cheol; Kim, Young Il; Jae, Hwan Jun; Park, Jae Hyung [Seoul National University College of Medicine, Seoul National University Hospital, Department of Radiology (Korea, Republic of)

    2015-10-15

    PurposeThis study was designed to analyze retrospectively the performance of cone-beam computed tomography (CBCT) hepatic arteriography in depicting tumors and their feeders and to investigate the related determining factors in chemoembolization for hepatocellular carcinoma (HCC).MethodsEighty-six patients with 142 tumors satisfying the imaging diagnosis criteria of HCC were included in this study. The performance of CBCT hepatic arteriography for chemoembolization per tumor and per patient was evaluated using maximum intensity projection images alone (MIP analysis) or MIP combined with multiplanar reformation images (MIP + MPR analysis) regarding the following three aspects: tumor depiction, confidence of tumor feeder detection, and trackability of tumor feeders. Tumor size, tumor enhancement, tumor location, number of feeders, diaphragmatic motion, portal vein enhancement, and hepatic artery to parenchyma enhancement ratio were regarded as potential determining factors.ResultsTumors were depicted in 125 (88.0 %) and 142 tumors (100 %) on MIP and MIP + MPR analysis, respectively. Imaging performances on MIP and MIP + MPR analysis were good enough to perform subsegmental chemoembolization without additional angiographic investigation in 88 (62.0 %) and 128 tumors (90.1 %) on per-tumor basis and in 43 (50 %) and 73 (84.9 %) on per-patient basis, respectively. Significant determining factors for performance in MIP + MPR analysis on per tumor basis were tumor size (p = 0.030), tumor enhancement (0.005), tumor location (p = 0.001), and diaphragmatic motion (p < 0.001).ConclusionsCBCT hepatic arteriography provided sufficient information for subsegmental chemoembolization by depicting tumors and their feeders in the vast majority of patients. Combined analysis of MIP and MPR images was essential to enhance the performance of CBCT hepatic arteriography.

  11. Investigating Self-Regulated Study Strategies among Postsecondary Students with and without Dyslexia: A Diary Method Study

    Science.gov (United States)

    Andreassen, Rune; Jensen, Magne S.; Bråten, Ivar

    2017-01-01

    We investigated the use of self-regulated study strategies among undergraduates with dyslexia by means of extensive web-based diary data, comparing their strategy use to that of matched students without dyslexia who completed the diary in the same period. Additionally, we examined the perceived benefits of using the recorded strategies in both…

  12. Blood glucose levels within 7 days after birth in preterm infants according to gestational age

    Directory of Open Access Journals (Sweden)

    Ju Young Yoon

    2015-12-01

    Full Text Available PurposeThis study investigated blood glucose levels in preterm babies according to gestational age (GA.MethodsSubjects were 141 preterm infants with a GA180 mg/dL.ResultsDuring the 7 days after birth, hypo- and hyperglycemia occurred in 29 (29 of 141, 20.6% and 42 (42 of 141, 29.8% neonates, respectively. During the first 2 hours, 18 neonates (12.8% exhibited hypoglycemia, and only 2 (2 of 141, 1.4% developed hyperglycemia. From 6 to 24 hours, hypo- and hyperglycemia were observed in 0 and 9 (9 of 141, 6.4% neonates, respectively. Infants small for their GA (SGA were at risk for hypoglycemia both within 24 hours (odds ratio [OR], 2.718; P=0.045 and during days 2 to 7 (OR, 4.454; P=0.006, and hyperglycemia during days 2 to 7 (OR, 3.200; P=0.005. Low 1-minite Apgar score was risk factor for both hypo- and hyperglycemia during days 2 to 7 (OR, 0.756; P=0.035 for hypoglycemia and OR, 0.789; P=0.016 for hyperglycemia. Both hypo- and hyperglycemia within 24 hours were less common in those who started feeding (OR, 0.294; P=0.013 for hypoglycemia and OR, 0.162; P=0.011 for hyperglycemia.ConclusionCareful blood glucose level monitoring is required in preterm infants, especially SGA infants or those with low Apgar score. Early feeding could be beneficial for maintaining euglycemia.

  13. The Investigation of the Social Entrepreneurship Characteristics of Social Studies Pre-Service Teachers

    Science.gov (United States)

    Yazici, Kubilay; Uslu, Salih; Arik, Soner

    2016-01-01

    The purpose of this study is to investigate the social entrepreneurship characteristics of social studies pre-service teachers in terms of various variables (gender, defining oneself as a social entrepreneur and grade). The data of the research were obtained on a volunteer basis from 253 pre-service teachers studying at the departments of social…

  14. Vitamin D deficiency in Korean children: prevalence, risk factors, and the relationship with parathyroid hormone levels

    Directory of Open Access Journals (Sweden)

    In Hyuk Chung

    2014-06-01

    Full Text Available PurposeThis study was performed to investigate the relationship between serum vitamin D and parathyroid hormone (PTH levels as well as to describe the prevalence and the risk factors of vitamin D deficiency (VDD in Korean children.MethodsParticipants were 1,212 children aged 4 to 15 years, who visited Bundang CHA Medical Center (located at 37°N between March 2012 and February 2013. Overweight was defined as body mass index≥85th percentile. Participants were divided into 4 age groups and 2 seasonal groups. VDD was defined by serum 25-hydroxyvitamin D (25OHD <20 ng/mL.ResultsThe level of 25OHD was significantly lower in overweight group than in normal weight group (17.1±5.1 ng/mL vs. 19.1±6.1 ng/mL, P<0.001. Winter-spring season (odds ratio [OR], 4.46; 95% confidence interval [CI], 3.45-5.77, older age group (OR, 1.60; 95% CI, 1.36-1.88, and overweight (OR, 2.21; 95% CI, 1.62-3.01 were independently related with VDD. The PTH levels were significantly higher in VDD group compared to vitamin D insufficiency and sufficiency group (P<0.001. In normal weight children, 25OHD (β=-0.007, P<0.001 and ionized calcium (β=-0.594, P=0.007 were independently related with PTH, however, these associations were not significant in overweight children.ConclusionVDD is very common in Korean children and its prevalence increases in winter-spring season, in overweight children and in older age groups. Further investigation on the vitamin D and PTH metabolism according to adiposity is required.

  15. Parents' perception about child's height and psychopathology in community children with relatively short stature

    Directory of Open Access Journals (Sweden)

    Jun-Won Hwang

    2015-06-01

    Full Text Available PurposeThis study investigated the relationship between height and psychopathology in community children with relatively short stature according to the parents' reports. Also, the matter of parental concern about child's height was explored.MethodsThe child behavior checklist (CBCL, the Brief Encounter Psychosocial Instrument (BEPSI, and the child-health questionnaire-parent form 50 (CHQ-PF50 were administered to 423 parents (from elementary and middle school children's in Gangnam, South Korea. Subjects were divided into three groups; (1 relatively short (n=30, (2 average stature (n=131, (3 relatively tall (n=153. CBCL, BEPSI, and CHQ-PF50 scores were compared among three groups.ResultsThere were no significant differences in psychosocial burden associated with relatively short stature measured by Korean version of the BEPSI and Korean version of the CBCL scores among three groups. But general health perception score of relatively short was significantly lower than that of nonshort on the CHQ-PF50. Also, they were more used complementary medicines, milk and growth hormone compared to the nonshort. The parents' expected height of their children was 180.6±3.5 cm for boys and 166.7±3.5 cm for girls. This is respectively 90 percentile and 75-90 percentile for the Korean standard adult height.ConclusionOur study shows that in Korea, Parents tended to regard relatively short children as having health problems. Also, the parental expectation for their child's attainable height is unrealistically tall, mostly due to lack of correct medical information.

  16. The analysis and investigation on basic data for development status study on the radioisotope industry

    International Nuclear Information System (INIS)

    Kim, In Hwan; Shim, H. S.; Chun, I. Y.; Jang, J. H.

    2005-12-01

    This study is intended to investigate and analysis the use degree of the radioisotope in domestic industry by the data of indirect information in focus of industry using the radioisotope per year basis. The contents and scope of this study is as follows: - Review of the industry sorting methods and application of the UNIDO(United Nation Industry Development organization). - Investigation of RI permitted companies and notified companies by 2003. 12. 31. - The Analysis and investigation of the basic data for the number of workers, wages and salaries of employees, product costs and the value added etc. of RI permitted companies from 1980

  17. The use of desk studies, remote sensing and surface geological and geophysical techniques in site investigations

    International Nuclear Information System (INIS)

    Mather, J.D.

    1984-02-01

    The geoscientific investigations required to characterise a site for the underground disposal of radioactive wastes involve a wide range of techniques and expertise. Individual national investigations need to be planned with the specific geological environment and waste form in mind. However, in any investigation there should be a planned sequence of operations leading through desk studies and surface investigations to the more expensive and sophisticated sub-surface investigations involving borehole drilling and the construction of in situ test facilities. Desk studies are an important and largely underestimated component of site investigations. Most developed countries have archives of topographical, geological and environmental data within government agencies, universities, research institutes and learned societies. Industry is another valuable source but here confidentiality can be a problem. However, in developing countries and in some regions of developed countries the amount of basic data, which needs to be collected over many decades, will not be as extensive. In such regions remote sensing offers a rapid method of examining large areas regardless of land access, vegetation or geological setting, rapidly and at relatively low cost. It can also be used to examine features, such as discontinuity patterns, over relatively small areas in support of intensive ground investigations. Examples will be given of how remote sensing has materially contributed to site characterisation in a number of countries, particularly those such as Sweden, Canada and the United Kingdom where the major effort has concentrated on crystalline rocks. The main role of desk studies and surface investigations is to provide basic data for the planning and execution of more detailed subsurface investigations. However, such studies act as a valuable screening mechanism and if they are carried out correctly can enable adverse characteristics of a site to be identified at an early stage before

  18. Comparative study of geological, hydrological, and geophysical borehole investigations

    International Nuclear Information System (INIS)

    Magnusson, K.A.; Duran, O.

    1984-09-01

    The understanding of the permeability of the bedrock can be improved by supplementing the results of the water injection tests with information from core mapping, TB-inspection and borehole geophysics. The comparison between different borehole investigations encompasses core mapping, TV-inspection and various geophysical bore hole measurements. The study includes data from two different study areas, namely Kraakemaala and Finnsjoen. In these two areas, extensive geological, hydrological and geophysical investigation have been carried out. The fractures and microfractures in crystalline rock constitute the main transport paths for both groundwater and electric currents. They will therefore govern both the permeability and the resistivity of the rock. In order to get a better understanding of the influence of fractures on permeability and resistivity, a detailed comparison has been made between the hydraulic conductivity, respectively, and the character of fractures in the core and the borehole wall. The fractures show very large variations in hydraulic conductivity. Microfractures and most of the thin fractures have no measurable hydraulic conductivity (in this case -9 m s -1 ), while test sections which contain a single isloated fracture can have no measurable, to rather high hydraulic conductivities (> 10 -7 m s -1 ). Wide fracture zones often have hydraulic conductivities which vary from very low (less than 2 x 10 -9 m s -1 ) to high values (10 -5 m s -1 ). This indicates that the hydraulic conductivity is governed by a few discrete fractures. The resistivity shows a continous variation in the range 1,000- 100,000 ohm-m and a relatively poor correlation with hydraulic conductivities. The observed difference is considered to the effect of restriction of water flow on a few channels, while electric surface condition, i.e. current transport through thin water films, makes current transport possible through fractures with very small aperatures. (Author)

  19. Forensic Polygraph in Crime Investigation: A Case Study

    Directory of Open Access Journals (Sweden)

    Aabad Ayoub

    2016-06-01

    Full Text Available A polygraph is an instrument that measures and records physiological changes inside the body. In the absence of a valid physical evidence, polygraphy may be a useful technique to verify truthfulness or detect deception. The present study was conducted to determine the truthfulness of a suspect in a murder case that was referred to PFSA for a polygraph examination. The stomach contents of the examinee and the hyoid bone of the vicvtim were submitted to the department of toxicology and forensic pathology at the PFSA, respectively. In the present study, integrated zone comparison technique (IZCT and forensic assessment interview technique (FAINT designed for specific and multi issue testing were used to examine the suspect. Computerized Academy for Scientific Investigative training (ASIT Algorithm and weighted scoring were applied in IZCT and FAINT scoring, respectively. The suspect of this murder case was brought to PFSA for polygraph examination. During the initial interview, the suspect denied any involvement in the said case. However, after complete polygraph examination, the suspect was proven to have been deceptive and later on confessed to police officials. The polygraph examination of the suspect proved him deceptive which was later confirmed by his confession. His stomach did not contain any toxic/ sedative material.

  20. A pilot investigation to optimise methods for a future satiety preload study.

    Science.gov (United States)

    Hobden, Mark R; Guérin-Deremaux, Laetitia; Commane, Daniel M; Rowland, Ian; Gibson, Glenn R; Kennedy, Orla B

    2017-01-01

    Preload studies are used to investigate the satiating effects of foods and food ingredients. However, the design of preload studies is complex, with many methodological considerations influencing appetite responses. The aim of this pilot investigation was to determine acceptability, and optimise methods, for a future satiety preload study. Specifically, we investigated the effects of altering (i) energy intake at a standardised breakfast (gender-specific or non-gender specific), and (ii) the duration between mid-morning preload and ad libitum lunch meal, on morning appetite scores and energy intake at lunch. Participants attended a single study visit. Female participants consumed a 214-kcal breakfast ( n  = 10) or 266-kcal breakfast ( n  = 10), equivalent to 10% of recommended daily energy intakes for females and males, respectively. Male participants ( n  = 20) consumed a 266-kcal breakfast. All participants received a 250-ml orange juice preload 2 h after breakfast. The impact of different study timings was evaluated in male participants, with 10 males following one protocol (protocol 1) and 10 males following another (protocol 2). The duration between preload and ad libitum lunch meal was 2 h (protocol 1) or 2.5 h (protocol 2), with the ad libitum lunch meal provided at 12.00 or 13.00, respectively. All female participants followed protocol 2. Visual analogue scale (VAS) questionnaires were used to assess appetite responses and food/drink palatability. Correlation between male and female appetite scores was higher with the provision of a gender-specific breakfast, compared to non-gender-specific breakfast (Pearson correlation of 0.747 and 0.479, respectively). No differences in subjective appetite or ad libitum energy intake were found between protocols 1 and 2. VAS mean ratings of liking, enjoyment, and palatability were all > 66 out of 100 mm for breakfast, preload, and lunch meals. The findings of this pilot study confirm the acceptability

  1. Investigation on mechanical properties of basalt composite fabrics (experiment study

    Directory of Open Access Journals (Sweden)

    Talebi Mazraehshahi H.

    2010-06-01

    Full Text Available To fully appreciate the role and application of composite materials to structures, correct understanding of mechanical behaviors required for selection of optimum material. Fabric reinforced composites are composed of a matrix that is reinforced with pliable fabric, glass fabric is most popular reinforcement for different application specially in aircraft structure, although other fabric material are also used. At this study new fabric material called basalt with epoxy resin introduced and mechanical behaviors of this material investigated from view point of testing. For this study two type of fabric with different thickness used. Comparison between this composite reinforcement with popular reinforcement as carbon, glass, kevlar performed. To determine mechanical properties of epoxy based basalt fabric following test procedure performed : 1. Tensile testing according to ASTM D3039 in 0° and 90° direction to find ultimate strength in tension and shear, modulus of elasticity, elangation and ultimate strain. 2. Compression testing according to EN 2850 ultimate compression strength and maximum deformation under compression loading. 3. Shear testing according to ASTM D3518-94 to find in plane shear response of polymer matrix composites materials. 4. Predict flexural properties of sandwich construction which manufactured from basalt facing with PVC foam core according to ASTM C393-94. Material strength properties must be based on enough tests of material to meet the test procedure specifications [1]. For this reason six specimens were manufactured for testing and the tests were performed on them using an INSTRON machine model 5582. In the study, the effect of percent of resin in basalt reinforced composite was investigated. Also the weights of the ballast based composites with different percent of resin were measured with conventional composites. As the weight is an important parameter in aerospace industry when the designer wants to replace one

  2. Toward a standardized investigation protocol in sudden unexpected deaths in infancy in South Africa: a multicenter study of medico-legal investigation procedures and outcomes.

    Science.gov (United States)

    du Toit-Prinsloo, Lorraine; Dempers, Johan; Verster, Janette; Hattingh, Christa; Nel, Hestelle; Brandt, V D; Jordaan, Joyce; Saayman, Gert

    2013-09-01

    South Africa manifests a socio-economic dichotomy that shows features of both a developed and developing country. As a result of this, areas exist where a lack of resources and expertise prevents the implementation of a highly standardized protocol for the investigation of sudden and unexpected deaths in infants (SUDI). Although the medico-legal mortuaries attached to academic centers have the capacity to implement standardized protocols, a previous study conducted at two large medico-legal mortuaries indicated otherwise. This study also revealed that the exact number and incidence of sudden infant death syndrome (SIDS) cases was unknown. These findings prompted a multicenter study of the medico-legal investigation procedures and outcomes in five academic centers in South Africa. A retrospective case audit was conducted for a 5-year period (2005-2009) at medico-legal laboratories attached to universities in Bloemfontein, Cape Town-Tygerberg, Durban, Johannesburg, and Pretoria. The total case load as well as the total number of infants younger than 1 year of age admitted to these mortuaries was documented. The case files on all infants younger than 1 year of age who were admitted as sudden and unexpected or unexplained deaths were included in the study population. Data collected on the target population included demographic details, the nature and scope of the post-mortem examinations, as well as the final outcome (cause of death). A total case load of 80,399 cases were admitted to the mortuaries over the 5 year period with a total of 3,295 (6.5 %) infants. In the infant group, 591 (0.7 %) died from non-natural causes and 2,704 (3.3 %) cases of sudden, unexpected and/or unexplained deaths in infants were admitted and included in the detailed case analysis study. One hundred and ninety-nine babies were between 0 and 7 days of age and 210 babies between 8 and 30 days. The remaining 2,295 infants were between 1 month and 12 months of age. Death scene investigation was

  3. Investigating different factors influencing job satisfaction: A case study of cement industry

    OpenAIRE

    Mina Shirvani; Asghar Mohammadi; Mohammad Reza Iravani; Saeed Yousef Pour; Allahyar Arabmomeni; Shirin Mirhaj; Akram Fakhri Fakhramini

    2013-01-01

    Job satisfaction plays an important role on increasing business productivity and efficiency. This paper presents an empirical investigation to study the relationship between job satisfaction and employees’ personal characteristics including gender, marital status, etc. The proposed study designs a questionnaire and distributes it among 244 out of 800 employees who worked for cement industry in Iran. The data are analyzed using different statistical tests such as t-student and analysis of vari...

  4. WAG 2 remedial investigation and site investigation site-specific work plan/health and safety checklist for the ecological assessment task, Kingfisher Study

    International Nuclear Information System (INIS)

    Holt, V.L.; Baron, L.A.

    1994-05-01

    This report provides specific details and requirements for the WAG 2 remedial investigation and site investigation Ecological Assessment Task, Kingfisher Study, including information that will contribute to safe completion of the project. The report includes historical background; a site map; project organization; task descriptions and hazard evaluations; controls; and monitoring, personal protective equipment, decontamination, and medical surveillance program requirements. The report also includes descriptions of site personnel and their certifications as well as suspected WAG 2 contaminants and their characteristics. The primary objective of the WAG 2 Kingfisher Study is to assess the feasibility of using kingfishers as biological monitors of contaminants on the Oak Ridge Reservation (ORR). Kingfisher sample collection will be used to determine the levels of contaminants and degree of bioaccumulation within a common piscivorous bird feeding on contaminated fish from streams on the ORR

  5. Study on geological environment in the Tono area. An approach to surface-based investigation

    International Nuclear Information System (INIS)

    2002-12-01

    Mizunami Underground Research (MIU) Project has aimed at preparation of basis of investigation, analysis and evaluation of geology of deep underground and basis of engineering technologies of ultra deep underground. This report stated an approach and information of surface-based investigation for ground water flow system and MIU Project by the following contents, 1) objects and preconditions, 2) information of geological environment for analysis of material transition and design of borehole, 3) modeling, 4) tests and investigations and 5) concept of investigation. The reference data consists of results of studies such as the geological construction model, topography, geologic map, structural map, linear structure and estimated fault, permeability, underground stream characteristics, the quality of underground water and rock mechanics. (S.Y.)

  6. Investigation of Public Charging Infrastructure : Case study Gränby sportfält

    OpenAIRE

    Dahl, Emma; Hedström, Andreas; Lindgren, Anna

    2017-01-01

    The municipal company Sportfastigheter AB is currently renovating and developing Gränby sportfält, a sports field in Uppsala. Adjacent to the sports field, a parking lot for 700 vehicles is located, where Sportfastigheter AB is preparing to install charging points for electric vehicles (EVs) at some of the places. This bachelor thesis aims to investigate how a public charging solution should be modeled, with the parking lot at Gränby sportfält as a case study. The investigation involves estim...

  7. An Investigation of Higher-Order Thinking Skills in Smaller Learning Community Social Studies Classrooms

    Science.gov (United States)

    Fischer, Christopher; Bol, Linda; Pribesh, Shana

    2011-01-01

    This study investigated the extent to which higher-order thinking skills are promoted in social studies classes in high schools that are implementing smaller learning communities (SLCs). Data collection in this mixed-methods study included classroom observations and in-depth interviews. Findings indicated that higher-order thinking was rarely…

  8. Wind Turbine Acoustic Investigation: Infrasound and Low-Frequency Noise--A Case Study

    Science.gov (United States)

    Ambrose, Stephen E.; Rand, Robert W.; Krogh, Carmen M. E.

    2012-01-01

    Wind turbines produce sound that is capable of disturbing local residents and is reported to cause annoyance, sleep disturbance, and other health-related impacts. An acoustical study was conducted to investigate the presence of infrasonic and low-frequency noise emissions from wind turbines located in Falmouth, Massachusetts, USA. During the…

  9. The Power of Natural Selection: A Guided Investigation of Three Case Studies

    Science.gov (United States)

    Beachly, William

    2010-01-01

    I describe a quantitative approach to three case studies in evolution that can be used to challenge college freshmen to explore the power of natural selection and ask questions that foster a deeper understanding of its operation and relevance. Hemochromatosis, the peppered moth, and hominid cranial capacity are investigated with a common algebraic…

  10. Ambient pressure sensitivity of microbubbles investigated through a parameter study

    DEFF Research Database (Denmark)

    Andersen, Klaus Scheldrup; Jensen, Jørgen Arendt

    2009-01-01

    Measurements on microbubbles clearly indicate a relation between the ambient pressure and the acoustic behavior of the bubble. The purpose of this study was to optimize the sensitivity of ambient pressure measurements, using the subharmonic component, through microbubble response simulations....... The behavior of two microbubbles corresponding to two different contrast agents was investigated as a function of driving pulse and ambient overpressure, pov. Simulations of Levovist using a rectangular driving pulse show an almost linear reduction in the subharmonic component as pov is increased. For a 20...... found, although the reduction is not completely linear as a function of the ambient pressure....

  11. Investigating the Problems and Needs of Infertile Patients Referring to Assisted Reproduction Centers: A Review Study

    OpenAIRE

    Fahimeh Hasanbeigi; Mitra Zandi; Zohreh Vanaki; Anoushirvan Kazemnejad

    2017-01-01

    Background: The provision of optimal care is the most important goal in nursing, the fulfillment of which requires the identification of clients’ problems and needs. However, based on the review of the literature, no review study has investigated the problems and needs of the infertile patients in Iran. Aim: The purpose of the present study was to investigate the problems and needs of the infertile patients referring to the assisted reproduction centers. Method: This review study was based on...

  12. An observational cohort study on pre-operative investigations and referrals: How far are we following recommendations?

    Science.gov (United States)

    Karim, Habib Md Reazaul; Yunus, Md; Bhattacharyya, Prithwis

    2016-01-01

    Background and Aims: Pre-operative investigations are often required to supplement information for risk stratification and assessing reserve for undergoing surgery. Although there are evidence-based recommendations for which investigations should be done, clinical practice varies. The present study aimed to assess the pre-operative investigations and referral practices and compare it with the standard guidelines. Methods: The present observational study was carried out during 2014–appen2015 in a teaching institute after the approval from Institute Ethical Committee. A designated anaesthesiologist collected data from the completed pre-anaesthetic check-up (PAC) sheets. Investigations already done, asked by anaesthesiologists as well as referral services sought were noted and compared with an adapted master table prepared from standard recommendations and guidelines. Data were expressed in frequencies, percentage and statistically analysed using INSTAT software (GraphPad Prism software Inc., La Zolla, USA). Results: Seventy-five out of 352 patients (42.67% male, 57.33% female; American Society of Anesthesiologists physical status I to III) were included in this study. Nearly, all patients attended PAC with at least 5 investigations done. Of them, 89.33% were subjected to at least one unnecessary investigation and 91.67% of the referral services were not required which lead to 3.5 ( SD ±1.64) days loss. Anaesthesiologist-ordered testing was more focused than surgeons. Conclusion: More than two-third of pre-operative investigations and referral services are unnecessary. Anaesthesiologists are relatively more rational in ordering pre-operative tests yet; a lot can be done to rationalise the practice as well as reducing healthcare cost. PMID:27601737

  13. Percutaneous Sclerotherapy of Congenital Slow-Flow Vascular Malformations of the Orbit

    Energy Technology Data Exchange (ETDEWEB)

    Chiramel, George Koshy, E-mail: gkchiramel@gmail.com; Keshava, Shyamkumar Nidugala, E-mail: aparna-shyam@yahoo.com; Moses, Vinu, E-mail: vinu@cmcvellore.ac.in; Mammen, Suraj, E-mail: surajmammen77@gmail.com [Christian Medical College, Department of Radiology (India); David, Sarada, E-mail: saradadavid@gmail.com [Christian Medical College, Department of Ophthalmology (India); Sen, Sudipta, E-mail: paedsur@cmcvellore.ac.in [Christian Medical College, Department of Pediatric Surgery (India)

    2015-04-15

    PurposeThis manuscript describes the clinical features, imaging findings, treatment details, and short-term outcomes of a series of congenital slow-flow vascular malformations.MethodsThis was a prospective study of congenital slow-flow vascular malformations involving the orbital region treated at a single institution with percutaneous sclerotherapy.ResultsTen patients presented during the study period, comprising eight venous malformations, one lymphatic malformation, and one veno-lymphatic malformation. Nine patients underwent percutaneous sclerotherapy under digital subtraction angiography guidance, of which three developed marked rise in intraocular pressure requiring lateral canthotomy. The treatments were performed in the presence of an ophthalmologist who measured the intraorbital pressure during and after the procedure. On follow-up, some of the patients required repeat sessions of sclerotherapy. All patients had improvement of symptoms on follow up after the procedure.ConclusionCongenital slow-flow vascular malformations of the orbital region are rare lesions that should be treated using a multidisciplinary approach. Monitoring of the intraorbital pressure is required both during and after the procedure to decide about the need for lateral canthotomy to reduce the transiently increased intraorbital pressure.

  14. Percutaneous Sclerotherapy of Congenital Slow-Flow Vascular Malformations of the Orbit

    International Nuclear Information System (INIS)

    Chiramel, George Koshy; Keshava, Shyamkumar Nidugala; Moses, Vinu; Mammen, Suraj; David, Sarada; Sen, Sudipta

    2015-01-01

    PurposeThis manuscript describes the clinical features, imaging findings, treatment details, and short-term outcomes of a series of congenital slow-flow vascular malformations.MethodsThis was a prospective study of congenital slow-flow vascular malformations involving the orbital region treated at a single institution with percutaneous sclerotherapy.ResultsTen patients presented during the study period, comprising eight venous malformations, one lymphatic malformation, and one veno-lymphatic malformation. Nine patients underwent percutaneous sclerotherapy under digital subtraction angiography guidance, of which three developed marked rise in intraocular pressure requiring lateral canthotomy. The treatments were performed in the presence of an ophthalmologist who measured the intraorbital pressure during and after the procedure. On follow-up, some of the patients required repeat sessions of sclerotherapy. All patients had improvement of symptoms on follow up after the procedure.ConclusionCongenital slow-flow vascular malformations of the orbital region are rare lesions that should be treated using a multidisciplinary approach. Monitoring of the intraorbital pressure is required both during and after the procedure to decide about the need for lateral canthotomy to reduce the transiently increased intraorbital pressure

  15. Local Control of Perivascular Malignant Liver Lesions Using Percutaneous Irreversible Electroporation: Initial Experiences

    Energy Technology Data Exchange (ETDEWEB)

    Eller, Achim, E-mail: Achim.Eller@uk-erlangen.de; Schmid, Axel, E-mail: axel.schmid@uk-erlangen.de [University Hospital Erlangen, University of Erlangen-Nuremberg, Department of Radiology (Germany); Schmidt, Joachim, E-mail: joachim.schmidt@kfa.imed.uni-erlangen.de [University Hospital Erlangen, University of Erlangen-Nuremberg, Department of Anesthesiology (Germany); May, Matthias, E-mail: matthias.may@uk-erlangen.de; Brand, Michael, E-mail: michael.brand@uk-erlangen.de; Saake, Marc, E-mail: marc.saake@uk-erlangen.de; Uder, Michael, E-mail: michael.uder@uk-erlangen.de; Lell, Michael, E-mail: michael.lell@uk-erlangen.de [University Hospital Erlangen, University of Erlangen-Nuremberg, Department of Radiology (Germany)

    2015-02-15

    PurposeThis study was designed to assess efficacy and safety in the treatment of perivascular malignant liver lesions using percutaneous, computed tomography (CT)-guided irreversible electroporation (IRE).MethodsFourteen patients (mean age 58 ± 11 years) with 18 malignant liver lesions were consecutively enrolled in this study. IRE was performed in patients not eligible for surgery and lesions abutting large vessels or bile ducts. Follow-up exams were performed using multislice-CT (MS-CT) or MRI.ResultsMedium lesion diameter was 20 ± 5 mm. Ten of 14 (71 %) were successfully treated with no local recurrence to date (mean follow-up 388 ± 160 days). One case left initial tumor control unclear and additional RFA was performed 4 weeks after IRE. Complications occurred in 4 of 14 (29 %) cases. In one case, intervention was terminated and abdominal bleeding required laparotomy. In two cases, a postinterventional hematothorax required intervention. In another case, abdominal bleeding could be managed conservatively. No complications related to the bile ducts occurred.ConclusionsPercutaneous IRE seems to be effective in perivascular lesions but is associated with a higher complication rate compared with thermoablative techniques.

  16. Waste Management Plan for the Oak Ridge National Remedial Investigation/Feasibility Study

    International Nuclear Information System (INIS)

    1988-04-01

    In accordance with the requirements of the Remedial Investigation/Feasibility Study (RI/FS) Project Quality Assurance Plan, this Waste Management Plan establishes clear lines of responsibility and authority, documentation requirements, and operational guidance for the collection, identification, segregation, classification, packaging, certification, and storage/disposal of wastes. These subjects are discussed in the subsequent sections of this document

  17. Waste Management Plan for the Oak Ridge National Remedial Investigation/Feasibility Study

    Energy Technology Data Exchange (ETDEWEB)

    1988-04-01

    In accordance with the requirements of the Remedial Investigation/Feasibility Study (RI/FS) Project Quality Assurance Plan, this Waste Management Plan establishes clear lines of responsibility and authority, documentation requirements, and operational guidance for the collection, identification, segregation, classification, packaging, certification, and storage/disposal of wastes. These subjects are discussed in the subsequent sections of this document.

  18. An investigation of pimary music education in Victorian schools: a single case study

    OpenAIRE

    Cosaitis, Wei

    2017-01-01

    This phenomenological research has employed a qualitative case study approach and investigates what practices are required in successful music curriculum development and quality music teaching within and without the music classroom in state-supported (government) primary schools in Victoria, Australia. To contextualize the study, issues involving the history of music education in Victorian government primary schools, current national and state music curricula, particular music teaching approa...

  19. Investigating Relational Aggression and Bullying for Girls' of Color in Oklahoma: A Phenomenological Study

    Science.gov (United States)

    Flynn, Gayle L.

    2016-01-01

    This qualitative research study, applying aspects of van Manen's framework for hermeneutic phenomenological research, was conducted to investigate the narratives of relationally aggressive girls of color. The study focused on nine adolescent girls of color who were ages 14-17 years old and exhibited aggressive/bullying behaviors representing the…

  20. A Naturalistic Investigation of Media Multitasking While Studying and the Effects on Exam Performance

    Science.gov (United States)

    Patterson, Michael C.

    2017-01-01

    The present study investigated the use of multiple digital media technologies, including social networking platforms, by students while preparing for an examination (media multitasking) and the subsequent effects on exam performance. The level of media multitasking (number of simultaneous media technologies) and duration of study were used as…

  1. A gender study investigating physics self-efficacy

    Science.gov (United States)

    Sawtelle, Vashti

    The underrepresentation of women in physics has been well documented and a source of concern for both policy makers and educators. My dissertation focuses on understanding the role self-efficacy plays in retaining students, particularly women, in introductory physics. I use an explanatory mixed methods approach to first investigate quantitatively the influence of self-efficacy in predicting success and then to qualitatively explore the development of self-efficacy. In the initial quantitative studies, I explore the utility of self-efficacy in predicting the success of introductory physics students, both women and men. Results indicate that self-efficacy is a significant predictor of success for all students. I then disaggregate the data to examine how self-efficacy develops differently for women and men in the introductory physics course. Results show women rely on different sources of self-efficacy than do men, and that a particular instructional environment, Modeling Instruction, has a positive impact on these sources of self-efficacy. In the qualitative phase of the project, this dissertation focuses on the development of self-efficacy. Using the qualitative tool of microanalysis, I introduce a methodology for understanding how self-efficacy develops moment-by-moment using the lens of self-efficacy opportunities. I then use the characterizations of self-efficacy opportunities to focus on a particular course environment and to identify and describe a mechanism by which Modeling Instruction impacts student self-efficacy. Results indicate that the emphasizing the development and deployment of models affords opportunities to impact self-efficacy. The findings of this dissertation indicate that introducing key elements into the classroom, such as cooperative group work, model development and deployment, and interaction with the instructor, create a mechanism by which instructors can impact the self-efficacy of their students. Results from this study indicate that

  2. Study protocol for a multicenter investigation of reablement in Norway.

    Science.gov (United States)

    Langeland, Eva; Langland, Eva; Tuntland, Hanne; Førland, Oddvar; Aas, Eline; Folkestad, Bjarte; Jacobsen, Frode F; Kjeken, Ingvild

    2015-09-15

    Reablement is a promising new rehabilitation model, which is being implemented in some Western countries to meet current and future needs for home-based services. There is a need for further investigation of the effects of reablement among community-dwelling adults in terms of clinical and economic outcomes. This study will investigate the effectiveness of reablement in home-dwelling adults compared with standard treatment in terms of daily activities, physical functioning, health-related quality of life, coping, mental health, use of health care services, and costs. The study is a multicenter controlled trial. In total, 44 Norwegian municipalities will participate, including eight municipalities as a control group. For three municipalities with two zones, one will be assigned to the control group and the other to the intervention group. The experimental group will be offered reablement and the control group standard treatment. The sample will comprise approximately 750 participants. People will be eligible if they are home-dwelling adults, understand Norwegian, and have functional decline. Participants will be assessed at baseline, and after 10 weeks, 6 months, and 12 months. The primary outcome will be activity and participation measured by the Canadian Occupational Performance Measure. Physical functioning will be measured by the Short Physical Performance Battery and health-related quality of life by the European Quality of Life Scale. Coping will be measured by the Sense of Coherence questionnaire and mental health by the Mental Health Continuum Short Form. Costs will be generated based on registered working hours in different professions. Data analyses will be performed according to intention to treat. Univariate analysis of covariance will be used to investigate differences between the groups at baseline and the end of intervention. The data will be organized into two levels using a multilevel structure, i.e., individuals and municipalities, which will be

  3. An investigation of breast cancer risk factors in Cyprus: a case control study

    Directory of Open Access Journals (Sweden)

    Hadjisavvas Andreas

    2010-08-01

    Full Text Available Abstract Background Breast cancer is the most common form of malignancy affecting women worldwide. It is also the leading cancer in females in Cyprus, with approximately 400 new cases diagnosed annually. It is well recognized that genetic variation as well as environmental factors modulate breast cancer risk. The main aim of this study was to assess the strength of associations between recognized risk factors and breast cancer among Cypriot women. This is the first epidemiological investigation on risk factors of breast cancer among the Cypriot female population. Methods We carried out a case-control study, involving 1,109 breast cancer patients and a group of 1,177 controls who were recruited while participating in the National screening programme for breast cancer. Information on demographic characteristics and potential risk factors were collected from both groups during a standardized interview. Logistic regression analysis was used to assess the strength of the association between each risk factor and breast cancer risk, before and after adjusting for the possible confounding effect of other factors. Results In multivariable models, family history of breast cancer (OR 1.64, 95% CI 1.23, 2.19 was the strongest predictor of breast cancer risk in the Cypriot population. Late menarche (OR 0.64, 95% CI 0.45, 0.92 among women reaching menarche after the age of 15 vs. before the age of 12 and breastfeeding (OR 0.74, 95% CI 0.59, 0.92 exhibited a strong protective effect. In the case of breastfeeding, the observed effect appeared stronger than the effect of pregnancy alone. Surprisingly, we also observed an inverse association between hormone replacement therapy (HRT although this may be a product of the retrospective nature of this study. Conclusion Overall the findings of our study corroborate with the results of previous investigations on descriptive epidemiology of risk factors for breast cancer. This investigation provides important background

  4. Investigating Lebanese Grade Seven Biology Teachers Mathematical Knowledge and Skills: A Case Study

    Science.gov (United States)

    Raad, Nawal Abou; Chatila, Hanadi

    2016-01-01

    This paper investigates Lebanese grade 7 biology teachers' mathematical knowledge and skills, by exploring how they explain a visual representation in an activity depending on the mathematical concept "Function". Twenty Lebanese in-service biology teachers participated in the study, and were interviewed about their explanation for the…

  5. Investigation of biomaterials by human epithelial gingiva cells: an in vitro study

    Directory of Open Access Journals (Sweden)

    Neunzehn Jörg

    2012-12-01

    Full Text Available Abstract Introduction In modern medicine and dentistry the use of biomaterials is a fast developing field of increasing interest. Especially in dentistry the interaction between biomaterials like implant materials and the soft tissue in the oral cavity is in the focus of daily research. In this context the high importance of testing materials and their surfaces concerning their biocompatibility towards corresponding cells is very likely. For this purpose this study investigates cells derived from human gingival biopsies on different materials and surfaces. Methods Cells in this study were cultivated out of human biopsies by a grow out explant technique and were sub cultivated on titanium, zirconium dioxide and collagen membrane specimens. To characterise the cells on the material surfaces used in this study immunohistochemical and histological staining techniques as well as different methods of microscopy (light microscopy and SEM were applied. Results With the aid of the explant technique and the chosen cell cultivation method it was possible to investigate the human gingiva derived cells on different materials. The data of the present study show that the human gingival cells attach and proliferate on all three tested materials by exhibiting characteristic gingival keratinocyte protein expression even after long periods of culture e.g. up to 70 days. Conclusions It could be shown that the three tested materials titanium, zirconium dioxide and collagen membrane (and their special surfaces are good candidates for the application as materials in the dental gingival environment or, in the case of the collagen membrane as scaffold/cell-carrier for human gingival cells in tissue engineering.

  6. The association between skeletal maturation and adrenal androgen levels in obese children and adolescents

    Directory of Open Access Journals (Sweden)

    Sung Eun Kim

    2017-06-01

    Full Text Available PurposeThis study aimed to investigate the association between skeletal maturation and adrenal androgen levels in obese children and adolescents.MethodsFifty-three children and adolescents (aged 7–15 years diagnosed as obese or overweight were investigated. Anthropometric measurements, bone age (BA determination, serum biochemical analyses, and hormonal measurements were performed. The difference between BA and chronological age (BA–CA, dBACA was calculated and used to represent the degree of advanced skeletal maturation.ResultsThirty-one subjects were classified into the obese group and 22 subjects into the overweight group. Insulin resistance as calculated by the homeostasis model assessment of insulin resistance (HOMA-IR was significantly higher in the obese group than in the overweight group (4.03±2.20 vs. 2.86±1.11, P=0.026. The skeletal maturation of the obese group was advanced, but the dBACA did not differ between the obese and overweight groups statistically (1.43±1.35 vs. 0.91±1.15, P=0.141. Serum dehydroepiandrosterone sulfate (DHEA-S levels were significantly higher in subjects with dBACA>1 compared to those with dBACA≤1 (104.3±62.2 vs. 59.6±61.0, P=0.014. Correlation analyses demonstrated that dBACA was positively correlated with body mass index standard deviation scores (r=0.35, P=0.010, fasting insulin (r=0.36, P=0.009, HOMA-IR (r=0.30, P=0.031, and insulin-like growth factor-binding protein-3 (r=0.331, P=0.028. In multivariate linear regression analysis, HOMA-IR (P=0.026 and serum DHEA-S (P=0.032 were positively correlated with the degree of advanced skeletal maturation.ConclusionAdvanced skeletal maturation is associated with increased insulin resistance and elevated DHEA-S levels in obese children and adolescents.

  7. Remedial Investigation/Feasibility Study (RI/FS) process, elements and techniques guidance

    Energy Technology Data Exchange (ETDEWEB)

    1993-12-01

    This manual provides detailed guidance on Remedial Investigation/Feasibility Studies (RI/FSs) conducted pursuant to the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) at Department of Energy (DOE) facilities. The purpose of the RI/FS, to assess the risk posed by a hazardous waste site and to determine the best way to reduce that risk, and its structure (site characterization, risk assessment, screening and detailed analysis of alternatives, etc.) is defined in the National Oil and Hazardous Substances Pollution Contingency Plan (NCP) and further explained in the Environmental Protection Agency`s (EPA`s) Guidance for Conducting Remedial Investigations and Feasibility Studies Under CERCLA (Interim Final) 540/G-89/004, OSWER Directive 9355.3-01, October 1988. Though issued in 1988, the EPA guidance remains an excellent source of information on the conduct and structure of an RI/FS. This document makes use of supplemental RI/FS-related guidance that EPA has developed since its initial document was issued in 1988, incorporates practical lessons learned in more than 12 years of experience in CERCLA hazardous site remediation, and drawing on those lessons, introduces the Streamlined Approach For Environmental Restoration (SAFER), developed by DOE as a way to proceed quickly and efficiently through the RI/FS process at DOE facilities. Thus as its title implies, this guidance is intended to describe in detail the process and component elements of an RI/FS, as well as techniques to manage the RI/FS effectively.

  8. Investigating different factors influencing job satisfaction: A case study of cement industry

    Directory of Open Access Journals (Sweden)

    Mina Shirvani

    2013-10-01

    Full Text Available Job satisfaction plays an important role on increasing business productivity and efficiency. This paper presents an empirical investigation to study the relationship between job satisfaction and employees’ personal characteristics including gender, marital status, etc. The proposed study designs a questionnaire and distributes it among 244 out of 800 employees who worked for cement industry in Iran. The data are analyzed using different statistical tests such as t-student and analysis of variance. The results indicate that while there was not any meaningful relationship between gender and job satisfaction there was some meaningful relationship between marital status and job satisfaction.

  9. An investigation on how TQM influences employee performance: A case study of banking industry

    Directory of Open Access Journals (Sweden)

    Saeed Hakami Nasab

    2014-01-01

    Full Text Available This paper presents an empirical investigation to study the relationship between employee performance and TQM. The proposed study of this paper designs two questionnaires for TQM and performance measurement and distributes them among some employees who worked for one of Iranian banks in city of Semnan, Iran. The result of Kolmogorov–Smirnov test confirms that all data are normally distributed and the study uses Pearson correlation to investigate the relationship between various components of the survey. The result of the implementation of Pearson correlation ratio indicates that there was a positive and meaningful relationship between employee performance and TQM components (r=4.6223, P-value=0.000. In addition, there are some positive and meaningful relationships between TQM components and employee performance. The highest correlation belongs to relationship between employee performance and feedback (r=4.6223, P-value=0.000 followed by training and development (r = 0.441, P-value = 0.000 and communication (r = 4.2861, P-value = 0.000.

  10. A Mixed-Methods Study Investigating the Relationship between Media Multitasking Orientation and Grade Point Average

    Science.gov (United States)

    Lee, Jennifer

    2012-01-01

    The intent of this study was to examine the relationship between media multitasking orientation and grade point average. The study utilized a mixed-methods approach to investigate the research questions. In the quantitative section of the study, the primary method of statistical analyses was multiple regression. The independent variables for the…

  11. Geophysical and geological investigations of subsurface reservoirs : case studies of Spitsbergen, Norway

    Energy Technology Data Exchange (ETDEWEB)

    Baelum, Karoline

    2011-07-01

    The thesis gives a description of the subsurface and outcrop geology at a number of localities on Svalbard through a selection of various geophysical and geological methods. The localities represent a series of geological settings of varying scale, from near surface paleokarst and glacial environments to large scale geological features such as fault zones, grabens and dolerite intrusions. The geophysical and geological methods deployed likewise represent both detailed small scale investigations such as Lidar, radar and geoelectric investigations on and near the surface, and seismic investigations covering larger areas to a depth of several kilometers. The overall aim for all the studies has been to better understand reservoir and cap rock/ice systems in a barren arctic desert characterized by a frozen ground that challenges common geophysical methods. The investigations undertaken in connection with this thesis cover several areas The first part addresses the Billefjorden fault zone (BFZ) with its eastern hanging wall classic rift-basin. This fault zone can be traced for more than 200 km as a lineament that runs almost the entire length of Spitsbergen, from Wijdefjorden in the north to Storfjorden in the south. The seismic data along with surface observations and Lidar scans illustrate the long and complicated history of the BFZ and associated basin, from the initial formation via linkage of reverse faults in the Devonian, through Carboniferous reactivation as a normal fault with adjacent rift-basin in an extensional tectonic regime, to finally Tertiary contraction seen as fault reactivation and basin inversion in connection with the formation of the west-coast fold and thrust-belt. Especially the development of the Carboniferous rift-basin is of interest. An integrated study by seismic and georadar mapping, and Lidar data interpretation combined with outcrop analysis of faults and sedimentary succession, have shed new, detailed information on the good sandstone

  12. Embolization for Thoracic Duct Collateral Leakage in High-Output Chylothorax After Thoracic Surgery

    International Nuclear Information System (INIS)

    Kariya, Shuji; Nakatani, Miyuki; Yoshida, Rie; Ueno, Yutaka; Komemushi, Atsushi; Tanigawa, Noboru

    2017-01-01

    PurposeThis study was designed to investigate thoracic duct collateral leakage and the supply route of lymphatic fluid by lymphangiography and transcatheter thoracic ductography and to evaluate the results of embolization for thoracic duct collateral leakage performed to cut off this supply route.MethodsData were retrospectively collected from five patients who underwent embolization for thoracic duct collateral leakage in persistent high-output chylothorax after thoracic surgery. Extravasation of lipiodol at the ruptured thoracic duct collaterals was confirmed in all patients on lymphangiography. Transcatheter thoracic ductography was used to identify extravasation of iodinated contrast agent and to identify communication between the thoracic duct and leakage site. Thoracic duct embolization (TDE) was performed using the percutaneous transabdominal approach to cut off the supply route using N-butyl cyanoacrylate (NBCA) mixed with lipiodol (1:5–1:20).ResultsClinical success (drainage volume ≤10 mL/kg/day within 7 days after TDE) was achieved in all patients. The collateral routes developed as consequence of surgical thoracic duct ligation. In three patients, NBCA-Lipiodol reached the leakage site through direct communication between the thoracic duct and the ruptured lymphatic duct. In the other two patients, direct communication and extravasation was not detected on thoracic ductography, and NBCA-Lipiodol did not reach the leakage site. However, NBCA-Lipiodol did reach the cisterna chyli, lumbar trunks, and some collateral routes via the cisterna chyli or lumbar lymphatics. As a result, leakage was stopped.ConclusionsTDE was effective for the management of leakage of the collaterals in high-output chylothorax after thoracic surgery.

  13. Embolization for Thoracic Duct Collateral Leakage in High-Output Chylothorax After Thoracic Surgery

    Energy Technology Data Exchange (ETDEWEB)

    Kariya, Shuji, E-mail: kariyas@hirakata.kmu.ac.jp; Nakatani, Miyuki, E-mail: nakatanm@hirakata.kmu.ac.jp; Yoshida, Rie, E-mail: yagir@hirakata.kmu.ac.jp; Ueno, Yutaka, E-mail: uenoyut@hirakata.kmu.ac.jp; Komemushi, Atsushi, E-mail: komemush@takii.kmu.ac.jp; Tanigawa, Noboru, E-mail: tanigano@hirakata.kmu.ac.jp [Kansai Medical University, Department of Radiology (Japan)

    2017-01-15

    PurposeThis study was designed to investigate thoracic duct collateral leakage and the supply route of lymphatic fluid by lymphangiography and transcatheter thoracic ductography and to evaluate the results of embolization for thoracic duct collateral leakage performed to cut off this supply route.MethodsData were retrospectively collected from five patients who underwent embolization for thoracic duct collateral leakage in persistent high-output chylothorax after thoracic surgery. Extravasation of lipiodol at the ruptured thoracic duct collaterals was confirmed in all patients on lymphangiography. Transcatheter thoracic ductography was used to identify extravasation of iodinated contrast agent and to identify communication between the thoracic duct and leakage site. Thoracic duct embolization (TDE) was performed using the percutaneous transabdominal approach to cut off the supply route using N-butyl cyanoacrylate (NBCA) mixed with lipiodol (1:5–1:20).ResultsClinical success (drainage volume ≤10 mL/kg/day within 7 days after TDE) was achieved in all patients. The collateral routes developed as consequence of surgical thoracic duct ligation. In three patients, NBCA-Lipiodol reached the leakage site through direct communication between the thoracic duct and the ruptured lymphatic duct. In the other two patients, direct communication and extravasation was not detected on thoracic ductography, and NBCA-Lipiodol did not reach the leakage site. However, NBCA-Lipiodol did reach the cisterna chyli, lumbar trunks, and some collateral routes via the cisterna chyli or lumbar lymphatics. As a result, leakage was stopped.ConclusionsTDE was effective for the management of leakage of the collaterals in high-output chylothorax after thoracic surgery.

  14. Efficacy and Safety of Endovascular Intervention for the Management of Primary Entire-Inferior Vena Cava Occlusion

    International Nuclear Information System (INIS)

    Zhang, Qingqiao; Huang, Qianxin; Shen, Bin; Sun, Jingmin; Wang, Xiaolong; Liu, Hongtao

    2015-01-01

    PurposeThis study was designed to investigate the safety and efficacy of endovascular intervention for the treatment of primary entire-inferior vena cava (IVC) occlusion.MethodsEndovascular interventions were performed in six patients for the treatment of primary entire-IVC occlusion. IVC and hepatic venography were performed via the jugular and femoral veins. Balloon angioplasty was used to revascularize the hepatic vein and IVC and a stent was placed in the IVC to maintain patency. Postoperative color Doppler ultrasonography was performed at 1, 3, 6, and 12 months, and then annually, to monitor the patency of the hepatic vein and IVC.ResultsThe IVC and one or two hepatic veins were successfully revascularized in five patients. Revascularization was successful in the right and left hepatic veins in one patient; however, IVC patency could not be established in this patient. Eleven Z-type, self-expanding stents were placed into the IVCs of five patients (three stents in two patients, two stents in two patients, and one stent in one patient). There were no instances of postoperative bleeding or mortality. Follow-up was conducted for 18–90 months (42.8 ± 26.5 months). None of the five patients suffered restenosis of the IVC or hepatic veins. However, there was one of the six cases of right hepatic vein restenosis at 18 months postprocedure that was revascularized after a second balloon dilatation.ConclusionsEndovascular intervention is safe and efficacious for the treatment of primary entire-IVC occlusion

  15. A Review of Empirical Studies Investigating Antecedents and Consequences of Collective Learning Behaviors in Hospitals

    Directory of Open Access Journals (Sweden)

    Florina D. Spânu

    2013-01-01

    Full Text Available This study is a systematic review of the field research conducted in medical settings investigating collective learning behaviors. The review was driven by several research foci. Our main interest was in identifying antecedents and consequences of collective learning in hospitals. We also report results on the types of research questions addressed, research designs used, and types of medical teams investigated. Twelve studies met our inclusion criteria. Our findings revealed that highly contextualized studies that use different ways of measuring learning, different ways of conceptualizing medical teams, and different research methodologies, discuss similar antecedents. Variables like leadership behaviors, unit interpersonal climate, and hierarchical position were found to play a role in explaining organizational learning in hospitals across studies. We also found that despite an intense public discourse on the link between collective learning processes and patients’ safety and medical organizations’ performance, few studies actually report empirical data supporting this relationship.

  16. R and D Requirements, RF Gun Mode Studies, FEL-2 Steady-State Studies, Preliminary FEL-1 Time-Dependent Studies, and Preliminary Layout Option Investigation

    International Nuclear Information System (INIS)

    Byrd, John; Corlett, John; Doolittle, Larry; Fawley, William; Lidia, Steven; Penn, Gregory; Ratti, Alex; Staples, John; Wilcox Russell; Wurtele, Jonathan; Zholents, Alexander

    2005-01-01

    This report constitutes the third deliverable of LBNLs contracted role in the FERMI (at) Elettra Technical Optimization study. It describes proposed RandD activities for the baseline design of the Technical Optimization Study, initial studies of the RF gun mode-coupling and potential effects on beam dynamics, steady-state studies of FEL-2 performance to 10 nm, preliminary studies of time-dependent FEL-1 performance using electron bunch distribution from the start-to-end studies, and a preliminary investigation of a configuration with FEL sinclined at a small angle from the line of the linac

  17. Investigation of air pollutants in rural nursery school - a case study

    Science.gov (United States)

    Mainka, Anna; Zajusz-Zubek, Elwira; Kozielska, Barbara; Brągoszewska, Ewa

    2018-01-01

    Children's exposure to air pollutants is an important public health challenge. Indoor air quality (IAQ) in nursery school is believed to be different from elementary school. Moreover, younger children are more vulnerable to air pollution than higher grade children because they spend more time indoors, and their immune systems and bodies are less mature. The purpose of this study was to evaluate the indoor air quality (IAQ) at naturally ventilated rural nursery schools located in Upper Silesia, Poland. We investigated the concentrations of volatile organic compounds (VOCs), particulate matter (PM), bacterial and fungal bioaerosols, as well as carbon dioxide (CO2) concentrations in younger and older children's classrooms during the winter and spring seasons. The concentration of the investigated pollutants in indoor environments was higher than those in outdoor air. The results indicate the problem of elevated concentrations of PM2.5 and PM10 inside the examined classrooms, as well as that of high levels of CO2 exceeding 1,000 ppm in relation to outdoor air. The characteristics of PM and CO2 levels were significantly different, both in terms of classroom occupation (younger or older children) and of season (winter or spring).

  18. Spectroscopic studies and quantum chemical investigations of (3,4-dimethoxybenzylidene) propanedinitrile.

    Science.gov (United States)

    Gupta, Ujval; Kumar, Vinay; Singh, Vivek K; Kant, Rajni; Khajuria, Yugal

    2015-04-05

    The Fourier Transform Infrared (FTIR), Ultra-Violet Visible (UV-Vis) spectroscopy and Thermogravimetric (TG) analysis of (3,4-dimethoxybenzylidene) propanedinitrile have been carried out and investigated using quantum chemical calculations. The molecular geometry, harmonic vibrational frequencies, Mulliken charges, natural atomic charges and thermodynamic properties in the ground state have been investigated by using Hartree Fock Theory (HF) and Density Functional Theory (DFT) using B3LYP functional with 6-311G(d,p) basis set. Both HF and DFT methods yield good agreement with the experimental data. Vibrational modes are assigned with the help of Vibrational Energy Distribution Analysis (VEDA) program. UV-Visible spectrum was recorded in the spectral range of 190-800nm and the results are compared with the calculated values using TD-DFT approach. Stability of the molecule arising from hyperconjugative interactions, charge delocalization have been analyzed using natural bond orbital (NBO) analysis. The results obtained from the studies of Highest Occupied Molecular Orbital (HOMO) and Lowest Unoccupied Molecular Orbital (LUMO) are used to calculate molecular parameters like ionization potential, electron affinity, global hardness, electron chemical potential and global electrophilicity. Copyright © 2014 Elsevier B.V. All rights reserved.

  19. Comparison of different methods for work accidents investigation in hospitals: A Portuguese case study.

    Science.gov (United States)

    Nunes, Cláudia; Santos, Joana; da Silva, Manuela Vieira; Lourenço, Irina; Carvalhais, Carlos

    2015-01-01

    The hospital environment has many occupational health risks that predispose healthcare workers to various kinds of work accidents. This study aims to compare different methods for work accidents investigation and to verify their suitability in hospital environment. For this purpose, we selected three types of accidents that were related with needle stick, worker fall and inadequate effort/movement during the mobilization of patients. A total of thirty accidents were analysed with six different work accidents investigation methods. The results showed that organizational factors were the group of causes which had the greatest impact in the three types of work accidents. The methods selected to be compared in this paper are applicable and appropriate for the work accidents investigation in hospitals. However, the Registration, Research and Analysis of Work Accidents method (RIAAT) showed to be an optimal technique to use in this context.

  20. Investigation of publication bias in meta-analyses of diagnostic test accuracy: a meta-epidemiological study

    NARCIS (Netherlands)

    van Enst, W. Annefloor; Ochodo, Eleanor; Scholten, Rob J. P. M.; Hooft, Lotty; Leeflang, Mariska M.

    2014-01-01

    The validity of a meta-analysis can be understood better in light of the possible impact of publication bias. The majority of the methods to investigate publication bias in terms of small study-effects are developed for meta-analyses of intervention studies, leaving authors of diagnostic test

  1. Creep investigation of GFRP RC Beams - Part A : Literature review and experimental Study

    Directory of Open Access Journals (Sweden)

    masmoudi abdelmonem

    2014-11-01

    This paper (Part A presents a literature review and the loading history of six experimental beams reinforced with GFRP and steel bars. The results of this study revealed that Beams reinforced with GFRP are less marked with creep phenomenon.  This investigation should guide the civil engineer/designer for a better understanding creep phenomenon in GFRP reinforced concrete members.

  2. Investigating the Failure of State Owned Enterprises (SOEs of an Emerging Economy: A Comparative Case Study

    Directory of Open Access Journals (Sweden)

    Rajib Salah Uddin

    2016-08-01

    Full Text Available This study investigates the failure and aftermath of state owned enterprises (SOEs of an emerging economy, Bangladesh. Failure of SOEs of emerging economy has been investigated by many researchers during the last few decades. This study is an extension of previous research. Through the comparative case study, this study tries to explore the scenario of failure of SOEs, the causal factors of failure, remedial actions and aftermath in SOEs. The findings indicate that different authorities from the policy maker to the operating level employees cannot avoid the responsibilities for failure. Even proper restructuring within the ownership of government can drive the firm positively. It is expected that the comparative case study will help to make the decision for the concerned authorities of Bangladesh as well as the authorities of other countries of the world who are in the same position.

  3. Investigation of indoor air quality at residential homes in Hong Kong - case study

    International Nuclear Information System (INIS)

    Shun Cheng Lee; Waiming Li; Chiohang Ao

    2002-01-01

    Indoor air quality (IAQ) has been a matter of public concern in Hong Kong. Recently, the Hong Kong Government has recognized the potential risk and problems related to indoor air pollution, and it is striving to establish IAQ objectives for different types of indoor environments. This study attempts to provide more information about the present IAQ of local resident flats. Air pollutants measured in this study included carbon dioxide (CO 2 ), respirable suspended particulate matter (PM 10 ), formaldehyde (HCHO), volatile organic compounds (VOCs) and airborne bacteria. The results of this study indicate that the 8-h average concentrations of CO 2 and PM 10 in the domestic kitchens investigated were 14% and 67% higher than those measured in the living rooms. The indoor air pollution caused by PM 10 was more serious in domestic kitchens than in living rooms as almost all of the kitchens investigated had higher indoor levels of PM 10 . The majority of the domestic living rooms and kitchens studied had average concentrations of airborne bacteria higher than 500CFU/m 3 . The mean total bacteria count recorded in kitchens was greater than that obtained in living rooms by 23%. In homes where occupants smoke, the negative impact of benzene, toluene and m,p-xylene on the IAQ was greatly enhanced. The use of liquefied petroleum gas (LPG) stove has more significant impact on indoor VOCs than the use of cooking stoves with natural gas as cooking fuel. (Author)

  4. Investigating Learning Strategies for Vocabulary Development: A Comparative Study of Two Universities of Quetta, Pakistan

    Science.gov (United States)

    Fatima, Irum; Pathan, Zahid Hussain

    2016-01-01

    The primary purpose of this research is to investigate the vocabulary learning strategies employed by the undergraduate students of Sardar Bahadur Khan Women's University (SBKWU) and University of Balochistan (UOB), Quetta, Pakistan. A quantitative design was employed in this study to answer the two research questions of the present study. The…

  5. INVESTIGATION OF UNIVERSITY STUDENTS’ EFL WRITING APPREHENSION: A LONGITUDINAL STUDY IN CROATIA

    Directory of Open Access Journals (Sweden)

    Moira Kostić Bobanović

    2016-03-01

    Full Text Available Writing apprehension defines a person's ability to write under various stress types. Depending on a situation, an average person might perform below expectations, or be less apprehensive about writing than a professional. The purpose of this research is to investigate Croatian University students’ English as a foreign language writing apprehension. For the purpose to determine if the variables of students' gender and academic level (age play a role in their writing apprehension, we adapted WAT (Writing Apprehension Test so this would be tailored to our study popu-lation. A longitudinal study was conducted among the students who were studying at the University of Juraj Dobrila, Pula. The participants were tested twice: in the first and in the third year. The results of the study indicated that, in contrary to respondents’ gender, academic level was significant variable in their estimates of writing apprehension. In accordance with the findings stated above, a number of recommendations for handling writing apprehension were set.

  6. 200 Areas Remedial Investigation/Feasibility Study Implementation Plan - Environmental Restoration Program

    International Nuclear Information System (INIS)

    Knepp, A. J.

    1999-01-01

    The 200 Areas Remedial Investigation/Feasibility Study Implementation Plan - Environmental Restoration Program (Implementation Plan) addresses approximately 700 soil waste sites (and associated structures such as pipelines) resulting from the discharge of liquids and solids from processing facilities to the ground (e.g., ponds, ditches, cribs,burial grounds) in the 200 Areas and assigned to the Environmental Restoration Program. The Implementation Plan outlines the framework for implementing assessment activities in the 200 Areas to ensure consistency in documentation, level of characterization, and decision making. The Implementation Plan also consolidates background information and other typical work plan materials, to serve as a single referenceable source for this type of information

  7. Investigating Music Information Objects

    Science.gov (United States)

    Weissenberger, Lynnsey K.

    2016-01-01

    This dissertation, titled "Investigating Music Information Objects," is a study of the nature, description, representations, and ideas related to music information objects (MIOs). This research study investigates how music practitioners from various traditions describe and conceptualize MIOs, using a theoretical framework to classify…

  8. Implementation of a Sustainable Training System for Emergency in Vietnam

    Directory of Open Access Journals (Sweden)

    Sunjoo Kang

    2018-01-01

    Full Text Available PurposeThis study analyzed the project outcomes to share lessons regarding the development of an emergency medicine education system in Vietnam.MethodsRetrospective evaluation was implemented using project outcome indicators.ResultsA total of 13 training courses were administered, with the collaboration of international experts in Korea and Vietnam. A total of 23 kinds of emergency medicine education equipment were purchased, and a basic life support (BLS and two advanced cardiac life support labs were remodeled to provide appropriate simulation training. Throughout the 2 years of the project, nine Vietnamese BLS instructors were approved by the Korea Association of Cardiopulmonary Resuscitation under American Heart Association. Results of evaluation by Korean international development experts were based on five criteria, provided by the Development Assistance Committee of the Organization for Economic Co-operation and Development, were excellent. Success factors were identified as partnership, ownership, commitment, government support, and global networking.ConclusionProject indicators were all accomplished and received an excellent evaluation by external experts. For sustainable success, healthcare policy and legal regulation to promote high quality and safe service to the Vietnamese people are recommended.

  9. The Accordion Sign in the Transplant Ureter: Ramifications During Balloon Dilation of Strictures

    Energy Technology Data Exchange (ETDEWEB)

    Kriegshauser, J. Scott, E-mail: skriegshauser@mayo.edu; Naidu, Sailen G. [Mayo Clinic Hospital, Department of Radiology (United States); Chang, Yu-Hui H. [Mayo Clinic, Department of Biostatistics (United States); Huettl, Eric A. [Mayo Clinic Hospital, Department of Radiology (United States)

    2015-04-15

    PurposeThis study was designed to demonstrate the accordion sign within the transplant ureter and evaluate its ramifications during balloon dilation of strictures.MethodsA retrospective electronic chart and imaging review included demographic characteristics, procedure reports, and complications of 28 renal transplant patients having ureteral strictures treated with percutaneous balloon dilation reported in our transplant nephrology database during an 8-year period. The accordion sign was deemed present or absent on the basis of an imaging review and was defined as present when a tortuous ureter became kinked and irregular when foreshortened after placement of a wire or a catheter. Procedure-related urine leaks were categorized as occurring at the stricture if within 2 cm; otherwise, they were considered away from the stricture.ResultsThe accordion sign was associated with a significantly greater occurrence of leaks away from the stricture (P = 0.001) but not at the stricture (P = 0.34).ConclusionsThe accordion sign is an important consideration when performing balloon dilation procedures on transplant ureteral strictures, given the increased risk of leak away from the stricture. Its presence should prompt additional care during wire and catheter manipulations.

  10. Using discrepant events in science demonstrations to promote student engagement in scientific investigations: An action research study

    Science.gov (United States)

    Mancuso, Vincent J.

    Students' scientific investigations have been identified in national standards and related reform documents as a critical component of students' learning experiences in school, yet it is not easy to implement them in science classrooms. Could science demonstrations help science teachers put this recommendation into practice? While demonstrations are a common practice in the science classroom and research has documented some positive effects in terms of student motivation and engagement from their use, the literature also shows that, as traditionally presented, science demonstrations do not always achieve their intended outcomes. This, in turn, suggested the value of investigating what design elements of demonstrations could be used to promote specific instructional goals. Employing action research as a methodology, the proposed study was developed to explore how science demonstrations can be designed so as to most effectively promote student engagement in scientific investigations. More specifically, I was interested in examining the effects of using a discrepant event as part of the demonstration, as a way to create cognitive conflict and, thus, increase interest and engagement. I also investigated the relative merit of the well-researched POE (Predict, Observe, Explain) design versus employing demonstrations that appear to the student to be unplanned (what I will refer to as NOE, or a Naturally Occurring Experience). This study was informed by Constructivism, Situated Cognition and Conceptual Change as theoretical frameworks. The project included the design, implementation and study of an intervention consisting of three instructional units designed to support students' learning of the concepts of density, molecular arrangement of gas particles, and cohesion, respectively. In each of these units, lasting a total of two 80-minute class periods, students were asked to design and conduct an investigation to gain a better understanding of the concept under study. In

  11. Framing in criminal investigation

    Science.gov (United States)

    2016-01-01

    Failures in criminal investigation may lead to wrongful convictions. Insight in the criminal investigation process is needed to understand how these investigative failures may rise and how measures can contribute to the prevention of this kind of failures. Some of the main findings of an empirical study of the criminal investigation process in four cases of major investigations are presented here. This criminal investigation process is analyzed as a process of framing, using Goffman's framing (Goffman, 1975) and interaction theories (Goffman, 1990). It shows that in addition to framing, other substantive and social factors affect the criminal investigation. PMID:29046594

  12. Percutaneous Creation of Bare Intervascular Tunnels for Salvage of Thrombosed Hemodialysis Fistulas Without Recanalizable Outflow

    International Nuclear Information System (INIS)

    Chen, Matt Chiung-Yu; Wang, Yen-Chi; Weng, Mei-Jui

    2015-01-01

    PurposeThis study aimed to retrospectively assess the efficacy of a bare intervascular tunnel for salvage of a thrombosed hemodialysis fistula. We examined the clinical outcomes and provided follow-up images of the bare intervascular tunnel.Materials and MethodsEight thrombosed fistulas lacked available recanalizable outflow veins were included in this study. These fistulas were salvaged by re-directing access site flow to a new outflow vein through a percutaneously created intervascular tunnel without stent graft placement. The post-intervention primary and secondary access patency rates were calculated using the Kaplan–Meier method.ResultsThe procedural and clinical success rates were 100 %. Post-intervention primary and secondary access patency at 300 days were 18.7 ± 15.8 and 87.5 ± 11.7 %, respectively. The mean follow-up period was 218.7 days (range 10–368 days). One patient died of acute myocardial infarction 10 days after the procedure. No other major complications were observed. Minor complications, such as swelling, ecchymosis, and pain around the tunnel, occurred in all of the patients.ConclusionsPercutaneous creation of a bare intervascular tunnel is a treatment option for thrombosed hemodialysis fistulas without recanalizable outflow in selected patients

  13. How to achieve safe, high-quality clinical studies with non-Medicinal Investigational Products? A practical guideline by using intra-bronchial carbon nanoparticles as case study.

    Science.gov (United States)

    Berger, M; Kooyman, P J; Makkee, M; van der Zee, J S; Sterk, P J; van Dijk, J; Kemper, E M

    2016-08-19

    Clinical studies investigating medicinal products need to comply with laws concerning good clinical practice (GCP) and good manufacturing practice (GMP) to guarantee the quality and safety of the product, to protect the health of the participating individual and to assure proper performance of the study. However, there are no specific regulations or guidelines for non-Medicinal Investigational Products (non-MIPs) such as allergens, enriched food supplements, and air pollution components. As a consequence, investigators will avoid clinical research and prefer preclinical models or in vitro testing for e.g. toxicology studies. 1) briefly review the current guidelines and regulations for Investigational Medicinal Products; 2) present a standardised approach to ensure the quality and safety of non-MIPs in human in vivo research; and 3) discuss some lessons we have learned. We propose a practical line of approach to compose a clarifying product dossier (PD), comprising the description of the production process, the analysis of the raw and final product, toxicological studies, and a thorough risk-benefit-analysis. This is illustrated by an example from a human in vivo research model to study exposure to air pollutants, by challenging volunteers with a suspension of carbon nanoparticles (the component of ink cartridges for laser printers). With this novel risk-based approach, the members of competent authorities are provided with standardised information on the quality of the product in relation to the safety of the participants, and the scientific goal of the study.

  14. Investigator Argus X-12 study on the population of northern Croatia

    Directory of Open Access Journals (Sweden)

    Josip Crnjac

    2016-10-01

    Full Text Available Abstract X chromosome STR typing has emerged recently as a powerful tool, complementary to autosomal STR typing, in solving complex forensic and missing person cases. Investigator® Argus X-12 is a commercial product that allows co-amplification of 12 X chromosomal markers belonging to four linkage groups (LGs. In this study, we analyzed by capillary electrophoresis blood samples from 100 females and 102 males from a population of northern Croatia. Statistical analysis included calculation of allele and haplotype frequencies, as well as forensic parameters. The most informative marker for the northern Croatia population was DXS10135 with PIC=0.9211 and a total of 27 alleles. The least polymorphic marker was DXS8378 with 6 alleles. The proportion of observed haplotypes from the number of possible haplotypes varied from 2.74–8.57% across all LGs, with LG1 being the most informative. Of the 11 tested world populations compared to the population of northern Croatia, significant differences in genetic distance (FST were found for Greenlandic and all non-European populations. We found that all tested markers are in HWE and can thus be used for match probability calculation. Because of high combined power of discrimination in both men and women, Investigator® Argus X-12 is applicable for the northern Croatia population in routine forensic casework.

  15. Investigating Autism-Related Symptoms in Children with Prader-Willi Syndrome: A Case Study

    Directory of Open Access Journals (Sweden)

    Jeffrey A. Bennett

    2017-02-01

    Full Text Available Prader-Willi syndrome (PWS, a rare genetic disorder caused by the lack of expression of paternal genes from chromosome 15q11-13, has been investigated for autism spectrum disorder (ASD symptomatology in various studies. However, previous findings have been variable, and no studies investigating ASD symptomatology in PWS have exclusively studied children. We aimed to characterize social communication functioning and other ASD-related symptoms in children with PWS, and assessed agreement across measures and rates of ASD diagnosis. Measures included the Autism Diagnostic Observation Schedule-2 (ADOS-2, the Social Communication Questionnaire (SCQ, Social Responsiveness Scale-2 (SRS-2, Social Skills Improvement System-Rating Scales (SSIS-RS, and the Vineland Adaptive Behavioral Scales-II (VABS-II. General adaptive and intellectual skills were also assessed. Clinical best estimate (CBE diagnosis was determined by an experienced developmental pediatrician, based on history and review of all available study measures, and taking into account overall developmental level. Participants included 10 children with PWS, aged 3 to 12 years. Three of the 10 children were male and genetic subtypes were two deletion (DEL and eight uniparental disomy (UPD (with a total of 6 female UPD cases. Although 8 of the 10 children exceeded cut-offs on at least one of the ASD assessments, agreement between parent questionnaires (SCQ, SRS-2, SSIS-RS and observational assessment (ADOS-2 was very poor. None of the children were assigned a CBE diagnosis of ASD, with the caveat that the risk may have been lower because of the predominance of girls in the sample. The lack of agreement between the assessments emphasizes the complexity of interpreting ASD symptom measures in children with PWS.

  16. Investigating Autism-Related Symptoms in Children with Prader-Willi Syndrome: A Case Study.

    Science.gov (United States)

    Bennett, Jeffrey A; Hodgetts, Sandra; Mackenzie, Michelle L; Haqq, Andrea M; Zwaigenbaum, Lonnie

    2017-02-28

    Prader-Willi syndrome (PWS), a rare genetic disorder caused by the lack of expression of paternal genes from chromosome 15q11-13, has been investigated for autism spectrum disorder (ASD) symptomatology in various studies. However, previous findings have been variable, and no studies investigating ASD symptomatology in PWS have exclusively studied children. We aimed to characterize social communication functioning and other ASD-related symptoms in children with PWS, and assessed agreement across measures and rates of ASD diagnosis. Measures included the Autism Diagnostic Observation Schedule-2 (ADOS-2), the Social Communication Questionnaire (SCQ), Social Responsiveness Scale-2 (SRS-2), Social Skills Improvement System-Rating Scales (SSIS-RS), and the Vineland Adaptive Behavioral Scales-II (VABS-II). General adaptive and intellectual skills were also assessed. Clinical best estimate (CBE) diagnosis was determined by an experienced developmental pediatrician, based on history and review of all available study measures, and taking into account overall developmental level. Participants included 10 children with PWS, aged 3 to 12 years. Three of the 10 children were male and genetic subtypes were two deletion (DEL) and eight uniparental disomy (UPD) (with a total of 6 female UPD cases). Although 8 of the 10 children exceeded cut-offs on at least one of the ASD assessments, agreement between parent questionnaires (SCQ, SRS-2, SSIS-RS) and observational assessment (ADOS-2) was very poor. None of the children were assigned a CBE diagnosis of ASD, with the caveat that the risk may have been lower because of the predominance of girls in the sample. The lack of agreement between the assessments emphasizes the complexity of interpreting ASD symptom measures in children with PWS.

  17. A case study investigation of the indoor environmental noise in four urban South African hospitals

    CSIR Research Space (South Africa)

    Van Reenen, CA

    2015-11-01

    Full Text Available This multiple case study was designed to investigate acoustics in multi-bed general wards in four urban South African hospitals. Evidence-based research shows that a quiet indoor environment has positive outcomes for hospital patients and staff...

  18. Investigating the Relationship among Test Anxiety, Gender, Academic Achievement and Years of Study: A Case of Iranian EFL University Students

    Science.gov (United States)

    Rezazadeh, Mohsen; Tavakoli, Mansoor

    2009-01-01

    The construct of anxiety plays a major role in one's life. One of these anxieties is test anxiety or apprehension over academic evaluation. The present study was designed to investigate the relationship between gender, academic achievement, years of study and levels of test anxiety. This investigation is a descriptive analytic study and was done…

  19. Investigating the psychological impact of bank robbery: a cohort study.

    Science.gov (United States)

    Hansen, Maj; Armour, Cherie; Shevlin, Mark; Elklit, Ask

    2014-06-01

    Despite numerous annual bank robberies worldwide, research in the psychological sequelae of bank robberies is sparse and characterized by several limitations. To overcome these limitations we investigated the psychological impact of bank robbery in a cohort study by comparing general levels of traumatization and somatization in employees never exposed to robbery and employees exposed to robbery at different degrees and time-points, while controlling for selected risk factors of posttraumatic distress. Multivariate regression analyses showed that only the acute directly exposed robbery group which had a significantly higher score on general traumatization and somatization compared to the control group whilst controlling for other factors. In conclusion, bank robbery exposure appears to be especially associated with psychological distress in the acute phase and in victims present during the robbery. After the acute phase, other factors appear more important in predicting general traumatization and somatization in bank employees compared to exposure to robbery. Copyright © 2014 Elsevier Ltd. All rights reserved.

  20. Investigating Low-Carbon Agriculture: Case Study of China’s Henan Province

    Directory of Open Access Journals (Sweden)

    Min Su

    2017-12-01

    Full Text Available Developing low-carbon agriculture requires investigating the trajectory, decoupling statuses, and driving forces of agricultural carbon emissions. This study explored the evolution of agricultural carbon emissions based on 18 kinds of major carbon emission sources in Henan Province of China, which produces approximately one-tenth of China’s total grain output. We then analyzed the relationship between carbon emissions and economic growth using the decoupling elasticity model, and identified the factors driving the decoupling status. This analysis was done with a decoupling elasticity model, using the Logarithmic Mean Divisia Index technique. There were three key results: (1 Agricultural carbon emissions totaled 16.61 million tons in 1999, and increased by 7.99% to 17.93 million tons in 2014, with an average growth rate of approximately 0.65%; (2 The decoupling relationship between agricultural carbon emissions and economic output was dominated by weak decoupling during the study period; (3 Agricultural labor productivity was the leading contributor to changes in agricultural carbon emissions, followed by farming-animal husbandry carbon intensity, labor, and agricultural structure.

  1. Studies investigating economic, agricultural-economic and demographic factors influencing land use dynamics

    International Nuclear Information System (INIS)

    Mora, R.; San Juan, C.

    2009-01-01

    In this paper, we review studies investigating economic, agricultural-economic and demographic factors influencing land use dynamics, making special emphasis on the policy framework in the European Union. We find several conclusions, among which the following should be emphasized. First, this review highlights the existence of different methodologies to build up models to identify the effects of policy reforms affecting land use and desertification. Second, use of micro data to set up an econometric-process simulation model of land use has already been used with success. Third, in the geographical distribution of land use, prices drive all short and long-rung processes. Finally, logistic models have recently been used to study micro decisions at the agricultural sector to identify relative rents and land characteristics such as location and soil fertility as main determinants of land use patters. (Author) 8 refs.

  2. Vamistor resistor investigation

    Science.gov (United States)

    1973-01-01

    Results are presented of the failure investigation conducted on resistors produced by the Vamistor Divison, Wagner Electric Corporation. This failure investigation included; failure analyses, chemical and metallurgical analyses, failure mechanism studies, seal leak analyses, and nondestructive stress tests. The data, information, conclusions, and recommendation can be helpful in assessing current usage of these resistors.

  3. Isotope techniques in catchment behaviour studies with particular emphasis on snowmelt runoff investigations

    International Nuclear Information System (INIS)

    Yurtsever, Y.

    1984-05-01

    The dynamics of runoff occurring mainly by snowmelt have been investigated by the aid of environmental isotopes. Regular samples collected from river water and snow cover throughout 1978 to 1981 at two selected catchment basins in eastern Turkey were analysed for their oxygen-18, deuterium and tritium contents. The tritium results together with detailed hydrological and hydro-meteorological data have enabled to study the time distribution of various component flow systems involved in the total runoff resulting from snowmelt

  4. Investigations of portable cadmium telluride (CdTe(Cl)) detectors for clinical studies with radioactive indicators

    International Nuclear Information System (INIS)

    Bojsen, J.

    1985-01-01

    The combination of small, portable γ-radiation-sensitive Cadmium Telluride (CdTE(Cl)) crystal detectors and portable solid state data storage memories makes it feasible to extend the measuring period in a number of clinical investigations based on the use of various radioisotopes and external detection. Blood sampling can be avoided in some cases. Continuous ambulatory monitoring of relevant physiological parameters is practicable, e.g. kidney function (GFR), left ventricular ejection fraction, subcutaneous blood flow, muscle blood flow and insulin absorption in diabetic patients. In the present methodological study the applicability of the 133-Xe washout technique to subcutaneous (s.c.) adipose tissue blood flow (SBF) has been investigated and adapted to the use of CdTe(Cl) detectors attached to the skin surface for the measurement of local 133-Xe-disappearance rate constants (k). Physical characterization of CdTe(Cl) detectors as γ-sensitive devices has been performed, and adequate counting sensitivities were found without detector energy-resolution properties. The CdTe(Cl) detectors are therefore suitable for single indicator studies. The measuring geometry of CdTe(Cl) detectors was studied and compared with that of stationary Sodium Iodide (NaI(Tl)) detectors in both phantom and in vivo investigations. The spatial properties of CdTe(Cl) detectors could to some extent be adjusted by pulse height discrimination and lead collimation. When long-term measurements were complicated by for instance physical activity of the patients, the small CdTe(Cl) detectors in general showed equal or better performance than the heavy and voluminous NaI(Tl) detectors. The free movement of the ambulatory patient and the avoidance of cable connections to stationary data-collecting systems gave improved possibilities for measurements of the relevant parameters. From this point of view, portable CdTe(Cl) detectors must be considered an important advance for radioactivity studies in

  5. Remedial investigation/feasibility study of the Clinch River/Poplar Creek operable unit. Volume 5

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    This volume is in support of the findings of an investigation into contamination of the Clinch River and Poplar Creek near the Oak Ridge Reservation (for more than 50 years, various hazardous and radioactive substances have been released to the environment as a result of operations and waste management activities there). It addresses the quality assurance objectives for measuring the data, presents selected historical data, contains data from several discrete water characterization studies, provides data supporting the sediment characterization, and contains data related to several biota characterization studies.

  6. Investigating the Effect of Academic Procrastination on the Frequency and Variety of Academic Misconduct: A Panel Study

    Science.gov (United States)

    Patrzek, Justine; Sattler, Sebastian; van Veen, Floris; Grunschel, Carola; Fries, Stefan

    2015-01-01

    In prior studies, academic procrastination has been discussed as an influencing factor of academic misconduct. However, empirical studies were conducted solely cross-sectionally and investigated only a few forms of academic misconduct. This large scale web-based study examined the responses of between 1359 and 2207 participants from different…

  7. Comparison of the prevalence of islet autoantibodies according to age and disease duration in patients with type 1 diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Young Hwa Kong

    2013-06-01

    Full Text Available PurposeThis study investigated the prevalence of islet autoantibodies in children and adults with T1DM according to their age and the duration of disease.MethodsWe measured the levels of islet autoantibodies, including antiglutamic acid decarboxylase antibody (anti-GAD Ab, and combined these with anthropometric measurements and laboratory tests of 137 patients newly diagnosed with T1DM during the last 20 years. The subjects were subdivided into four groups according to their age at the onset of the disease. We then compared the prevalence of islet autoantibodies in the different age groups with the duration of disease.ResultsAmong the 137 patients, 68.9% tested positive for islet autoantibodies (71.4% within 1 year; 67.7% after 1 year of the disease onset. Within 1 year of the onset of the disease, 66.3% of the patients were positive for the anti-GAD Ab, and 35.6% were positive for IAAs. The prevalence of islet autoantibodies was significantly higher in the prepubertal groups than in the postpubertal groups (80.0% vs. 58.3%. The rate of positive islet autoantibodies changed with the duration of disease, and it differed according to the type of autoantibody and the age of the patient.ConclusionThe rates of positive islet autoantibodies were significantly higher in younger than in older patients at the time of the diagnosis of the disease. The positive rates were significantly changed 1 year after the onset of the disease in the preschool and the children groups. So these findings suggest that we need to diagnose type 1B diabetes distinguished T2DM in aldolescent group, carefully.

  8. Percutaneous Vertebroplasty for Pain Management in Patients with Multiple Myeloma: Is Radiofrequency Ablation Necessary?

    International Nuclear Information System (INIS)

    Orgera, Gianluigi; Krokidis, Miltiadis; Matteoli, Marco; Varano, Gianluca Maria; La Verde, Giacinto; David, Vincenzo; Rossi, Michele

    2014-01-01

    PurposeThis study was designed to investigate the added role of radiofrequency ablation (RFA) to vertebroplasty on the pain management of patients with multiple myeloma (MM).MethodsThirty-six patients (51–82 years) with vertebral localization of MM were randomly divided into two groups: 18 patients (group A) who underwent RFA and then vertebroplasty, and 18 patients (group B) who underwent only vertebroplasty. Primary endpoints were technical success and pain relief score rate measured by the visual analogue pain scores (VAS) and Roland–Morris Questionnaire (RMQ); secondary endpoint was the amount of administered analgesia. Survival and complications were compared.ResultsTechnical success was 100 % in both groups. The VAS score (at 24 h and 6 weeks postprocedure) decreased in equal manner for both groups from a mean of 9.1–3.4 and 2.0 for group A and from a mean of 9.3–3.0 and 2.3 for group B; RMQ mean score was 19.8 for group A and 19.9 for group B and decreased to a mean of 9.6 and 8.2 for group A and 9.5 and 8.7 for group B. The amount of medication was equally decreased in the two groups. No statistically significant difference was noted. No major complication occurred and two patients died from other causes.ConclusionsThe use of percutaneous vertebroplasty alone appears to be effective for the pain management of the patients with vertebral involvement of multiple myeloma. The use of RFA that includes cost and time does not offer any clear added benefit on the midterm pain management of such patients

  9. Percutaneous Vertebroplasty for Pain Management in Patients with Multiple Myeloma: Is Radiofrequency Ablation Necessary?

    Energy Technology Data Exchange (ETDEWEB)

    Orgera, Gianluigi [Sapienza Rome University, Department of Radiology, S. Andrea Hospital (Italy); Krokidis, Miltiadis, E-mail: mkrokidis@hotmail.com [Cambridge University Hospitals NHS Trust, Department of Radiology (United Kingdom); Matteoli, Marco; Varano, Gianluca Maria [Sapienza Rome University, Department of Radiology, S. Andrea Hospital (Italy); La Verde, Giacinto [Sapienza Rome University, Department of Medical Oncology, S. Andrea Hospital (Italy); David, Vincenzo; Rossi, Michele [Sapienza Rome University, Department of Radiology, S. Andrea Hospital (Italy)

    2013-05-08

    PurposeThis study was designed to investigate the added role of radiofrequency ablation (RFA) to vertebroplasty on the pain management of patients with multiple myeloma (MM).MethodsThirty-six patients (51–82 years) with vertebral localization of MM were randomly divided into two groups: 18 patients (group A) who underwent RFA and then vertebroplasty, and 18 patients (group B) who underwent only vertebroplasty. Primary endpoints were technical success and pain relief score rate measured by the visual analogue pain scores (VAS) and Roland–Morris Questionnaire (RMQ); secondary endpoint was the amount of administered analgesia. Survival and complications were compared.ResultsTechnical success was 100 % in both groups. The VAS score (at 24 h and 6 weeks postprocedure) decreased in equal manner for both groups from a mean of 9.1–3.4 and 2.0 for group A and from a mean of 9.3–3.0 and 2.3 for group B; RMQ mean score was 19.8 for group A and 19.9 for group B and decreased to a mean of 9.6 and 8.2 for group A and 9.5 and 8.7 for group B. The amount of medication was equally decreased in the two groups. No statistically significant difference was noted. No major complication occurred and two patients died from other causes.ConclusionsThe use of percutaneous vertebroplasty alone appears to be effective for the pain management of the patients with vertebral involvement of multiple myeloma. The use of RFA that includes cost and time does not offer any clear added benefit on the midterm pain management of such patients.

  10. Epidemiology and clinico-investigative study of organisms causing vaginal discharge

    Science.gov (United States)

    Venugopal, Swetha; Gopalan, Kannan; Devi, Asha; Kavitha, A.

    2017-01-01

    Background: Abnormal vaginal discharge is a common clinical problem in reproductive age group. It is the second most common problem after abnormal uterine bleeding. It is a neglected health problem, most commonly caused due to vulvovaginal candidiasis, trichomoniasis, and bacterial vaginosis (BV). Objectives: The present study was conducted to determine the prevalence of common organisms causing vaginal discharge and also to know the variety of clinical presentation. Materials and Methods: A cross-sectional descriptive study was conducted in the Skin and STD Outpatient Department of Vinayaka Mission Kirupananda Variyar Medical College Hospital, Salem, who presented with abnormal vaginal discharge between September 2012 and September 2014. A total of 100 women in the reproductive age group who had symptoms of vaginitis were examined. Data were coded and analyzed. Results: Out of the 100 patients examined, 77 (77%) cases were organism positive. Among the positive cases, BV (27%) was the most common microbiological cause of abnormal vaginal discharge, followed by trichomoniasis (25%), vaginal candidiasis (22%), combined infection (Candida and BV) (3%), and nonspecific cases (23%). Conclusion: Out of 100 cases, few cases showed discordance between clinical and laboratory diagnosis. This discordance can be due to pitfalls in identifying the causative agent clinically or obscuring of the findings due to improper treatment received for other ailments. Thus, clinico-investigative correlation is more important than other clinical findings alone. PMID:28442807

  11. Hantavirus Pulmonary Syndrome in Santa Cruz, Bolivia: Outbreak Investigation and Antibody Prevalence Study

    Science.gov (United States)

    Montgomery, Joel M.; Blair, Patrick J.; Carroll, Darin S.; Mills, James N.; Gianella, Alberto; Iihoshi, Naomi; Briggiler, Ana M.; Felices, Vidal; Salazar, Milagros; Olson, James G.; Glabman, Raisa A.; Bausch, Daniel G.

    2012-01-01

    We report the results of an investigation of a small outbreak of hantavirus pulmonary syndrome in 2002 in the Department of Santa Cruz, Bolivia, where the disease had not previously been reported. Two cases were initially reported. The first case was a physician infected with Laguna Negra virus during a weekend visit to his ranch. Four other persons living on the ranch were IgM antibody-positive, two of whom were symptomatic for mild hantavirus pulmonary syndrome. The second case was a migrant sugarcane worker. Although no sample remained to determine the specific infecting hantavirus, a virus 90% homologous with Río Mamoré virus was previously found in small-eared pygmy rice rats (Oligoryzomys microtis) trapped in the area. An antibody prevalence study conducted in the region as part of the outbreak investigation showed 45 (9.1%) of 494 persons to be IgG positive, illustrating that hantavirus infection is common in Santa Cruz Department. Precipitation in the months preceding the outbreak was particularly heavy in comparison to other years, suggesting a possible climatic or ecological influence on rodent populations and risk of hantavirus transmission to humans. Hantavirus infection appears to be common in the Santa Cruz Department, but more comprehensive surveillance and field studies are needed to fully understand the epidemiology and risk to humans. PMID:23094116

  12. Study on systemizing technology on investigation and analysis of deep underground geological environment. Japanese fiscal year, 2007 (Contract research)

    International Nuclear Information System (INIS)

    Kojima, Keiji; Ohnishi, Yuzo; Aoki, Kenji; Watanabe, Kunio; Nishigaki, Makoto; Tosaka, Hiroyuki; Shimada, Jun; Tochiyama, Osamu; Yoshida, Hidekazu; Ogata, Nobuhisa; Nishio, Kazuhisa

    2009-03-01

    In this year, the following studies were carried out with the aim of systemizing the technology on the investigation and analysis to understand the deep underground geological environment in relation to the radioactive waste disposal. (1) The study on the research and development (R and D) subjects which turned to the practical investigation and analysis of deep underground geological environment. (2) The study on the advanced technical basis for the investigation and analysis of deep underground geological environment. The results obtained from the studies are as follows: Regarding (1), the specific investigations, measurements and numerical and chemical analyses were performed particularly for research subjects: 1) engineering technology and 2) geological environment. Based on the results on (1), 3) tasks of collaboration research on intermediate area between the research fields, including the safety assessment field, were selected. Also redefinition of the NFC (Near Field Concept) were discussed. Regarding (2), based on the extracted tasks of JAEA (Japan Atomic Energy Agency) research project, the study was implemented considering previous R and D results and detailed research at the research field was carried out. This study contributed to the R and D development for its practical application. Concurrently, information exchange and discussion on the 2nd phase (the Construction Phase) of the MIU (Mizunami Underground Research Laboratory) research program were often held. (author)

  13. Nanostructured surfaces investigated by quantitative morphological studies

    International Nuclear Information System (INIS)

    Perani, Martina; Carapezzi, Stefania; Mutta, Geeta Rani; Cavalcoli, Daniela

    2016-01-01

    The morphology of different surfaces has been investigated by atomic force microscopy and quantitatively analyzed in this paper. Two different tools have been employed to this scope: the analysis of the height–height correlation function and the determination of the mean grain size, which have been combined to obtain a complete characterization of the surfaces. Different materials have been analyzed: SiO_xN_y, InGaN/GaN quantum wells and Si nanowires, grown with different techniques. Notwithstanding the presence of grain-like structures on all the samples analyzed, they present very diverse surface design, underlying that this procedure can be of general use. Our results show that the quantitative analysis of nanostructured surfaces allows us to obtain interesting information, such as grain clustering, from the comparison of the lateral correlation length and the grain size. (paper)

  14. Research Costs Investigated: A Study Into the Budgets of Dutch Publicly Funded Drug-Related Research

    NARCIS (Netherlands)

    T. van Asselt (Thea); B.L.T. Ramaekers (Bram); I. Corro Ramos (Isaac); M.A. Joore (Manuela); M.J. Al (Maiwenn); Lesman-Leegte, I. (Ivonne); M.J. Postma (Maarten); P. Vemer (Pepijn); T.L. Feenstra (Talitha)

    2017-01-01

    textabstractBackground: The costs of performing research are an important input in value of information (VOI) analyses but are difficult to assess. Objective: The aim of this study was to investigate the costs of research, serving two purposes: (1) estimating research costs for use in VOI analyses;

  15. INVESTIGATION OF IMPACTED SUPERNUMERARY TEETH: A CONE BEAM COMPUTED TOMOGRAPH (CBCT STUDY

    Directory of Open Access Journals (Sweden)

    Gökhan GÜRLER

    2017-10-01

    Full Text Available Purpose: The purpose of this study was to investigate the impacted supernumerary teeth which were initially detected on panoramic radiographs by using cone beam computed tomography (CBCT. Materials and Methods: In this retrospective study, supernumerary teeth diagnosed on panoramic radiographs taken from patients who had admitted for routine dental treatment were evaluated using CBCT. Patients’ age, gender, systemic conditions as well as number of supernumerary teeth, unilateral-bilateral presence, anatomical localization (maxilla, mandible, anterior-premolar-molar, mesiodens-lateral-canine, parapremolar-paramolar-distomolar shape (rudimentary, supplemental, tuberculate, odontoma, position (palatal-lingual-buccal-labial-central, shortest distance between the tooth and adjacent cortical plate, complications and treatment were assessed. Results: A total of 47 impacted supernumerary teeth in 34 patients were investigated in this study. Of these, 33 (70.2% were unilateral and 14 (29.8% were bilateral. Only 1 supernumerary tooth was found in 27 patients (79.4% whereas 7 patients (20.6% had 2 or more supernumerary teeth. Most of the teeth located in the anterior region (74.4% of the jaws and maxilla (74.4%. Twenty teeth (42.5% were mesiodens, 11 (23.4% were lateral or canine, 14 (29.7% were parapremolar and 2(4.4% were distomolar. Twenty-seven teeth (57.4% were rudimentary, 15 (31.9% were supplemental and 5 (10.7% were odontoma in shape. The shortest distance between the supernumerary tooth and adjacent cortical plate varied between 0 to 2.5 mm with a mean of 0.66 mm. The most common clinical complaint was the non-eruption of permanent teeth (42.5%. All supernumerary teeth were removed under local anesthesia. Orthodontic traction was performed for those impacted permanent teeth if necessary. Conclusion: Impacted supernumerary teeth are usually in close proximity to cortical bone. Although this may facilitate surgical access, there is a risk of

  16. Investigation of the Hammer-Gamma measurement technique: A feasibility study

    International Nuclear Information System (INIS)

    Showalter, R.

    1987-05-01

    As a reconnaissance tool for the determination of the approximate extent of shallow subsurface radium contamination, various detectors were evaluated to determine the most appropriate size for use in this task. Measurements were taken in the calibration models with existing instrumentation to determine sensitivities and calibration factors. Field measurements were taken to ensure subsurface contamination could be located with the instrumentation selected. Various methods of constructing a slim and shallow borehole were investigated to determine the easiest and quickest method of inserting the detector into the ground. Based on these investigations, a prototype ''Hammer-Gamma'' system was designed, built, and tested. 7 refs., 4 figs., 4 tabs

  17. Investigation of Physics Teacher Candidates' Cognitive Structures about "Electric Field": A Free Word Association Test Study

    Science.gov (United States)

    Türkkan, Ercan

    2017-01-01

    The aim of this study is to investigate the cognitive structures of physics teacher candidates about "electric field." Phenomenographic research method, one of the qualitative research patterns, was used in the study. The data of the study was collected from 91 physics teacher candidates who had taken General Physics II course at…

  18. An investigative study towards constructing anthropocentric Man-Machine System design evaluation methodology

    International Nuclear Information System (INIS)

    Yoshikawa, H.; Gofuku, A.; Itoh, T.; Sasaki, K.

    1992-01-01

    A methodological investigation has been conducted for evaluating the reliability of man-machine interaction in the total Man-Machine System (MMS) from the view-point of safety maintenance for emergent situations of nuclear power plant. Basic considerations in our study are: (i) what are the MMS design data to be evaluated, (ii) how are those MMS design data should be treated, and (iii) how the introduction effects of various operator support tools can be evaluated. The methods of both qualitative and quantitative MMS design evaluation are summarized in this paper, with the system architecture based on man-machine interaction simulation and the related cognitive human error factor analysis. (author)

  19. Research Costs Investigated : A Study Into the Budgets of Dutch Publicly Funded Drug-Related Research

    NARCIS (Netherlands)

    van Asselt, Thea; Ramaekers, Bram; Corro Ramos, Isaac; Joore, Manuela; Al, Maiwenn; Lesman-Leegte, Ivonne; Postma, Maarten; Vemer, Pepijn; Feenstra, Talitha

    BACKGROUND: The costs of performing research are an important input in value of information (VOI) analyses but are difficult to assess. OBJECTIVE: The aim of this study was to investigate the costs of research, serving two purposes: (1) estimating research costs for use in VOI analyses; and (2)

  20. Investigation of Acorn fruit Ash Efficiency in Cadmium Removal from Aqueous Solutions: Adsorption Isotherm and Kinetic Studies

    Directory of Open Access Journals (Sweden)

    Salman Zarei

    2014-12-01

    Full Text Available Background: Heavy metals are known as significant pollutants because of toxicity and nonbiodegradable characteristics. Cadmium is one of the heavy metals that have carcinogen potential. So, this study carried out in order to investigate the acorn fruit ash efficiency in cadmium removal from aqueous solutions. Methods: This study was done in the batch laboratory conditions. In this study, the effect of different parameters including pH, contact time, adsorbent dose, and initial cadmium concentration were evaluated. The Langmuir, Freundlich and Temkin isotherm models were used for analysis of the equilibrium isotherm. Adsorption kinetics of cadmium by different models were also investigated. The measurement of residual cadmium in the samples was determined by atomic absorption spectrophotometry at 228.8 nm. The SPSS-16 software was used for analysis of data. Results: According to the results, the maximum adsorption capacity of cadmium was 9.29 mg/g at pH=7 and 8 g/L adsorbent dose. The removal efficiency was increased with increasing contact time and decreased with increasing of cadmium initial concentration. Investigation of achieving data showed that the adsorption process followed better by Freundlich isotherm and the pseudo-second order kinetic. Conclusions: According to the results of this study, it could be concluded that the acorn fruit ash had high ability in cadmium adsorption and could be used as a cheap adsorbent in the removal of cadmium.

  1. Incorporating ecological risk assessment into remedial investigation/feasibility study work plans

    International Nuclear Information System (INIS)

    1994-06-01

    This guidance document (1) provides instructions on preparing the components of an ecological work plan to complement the overall site remedial investigation/feasibility study (RI/FS) work plan and (2) directs the user on how to implement ecological tasks identified in the plan. Under the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA), as amended by the Superfund Amendments and Reauthorization Act of 1986 (SARA), and RI/FS work plan will have to be developed as part of the site-remediation scoping process. Specific guidance on the RI/FS process and the preparation of work plans has been developed by the US Environmental Protection Agency (EPA 1988a). This document provides guidance to US Department of Energy (DOE) staff and contractor personnel for incorporation of ecological information into environmental remediation planning and decision making at CERCLA sites

  2. Incorporating ecological risk assessment into remedial investigation/feasibility study work plans

    Energy Technology Data Exchange (ETDEWEB)

    1994-06-01

    This guidance document (1) provides instructions on preparing the components of an ecological work plan to complement the overall site remedial investigation/feasibility study (RI/FS) work plan and (2) directs the user on how to implement ecological tasks identified in the plan. Under the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA), as amended by the Superfund Amendments and Reauthorization Act of 1986 (SARA), and RI/FS work plan will have to be developed as part of the site-remediation scoping process. Specific guidance on the RI/FS process and the preparation of work plans has been developed by the US Environmental Protection Agency (EPA 1988a). This document provides guidance to US Department of Energy (DOE) staff and contractor personnel for incorporation of ecological information into environmental remediation planning and decision making at CERCLA sites.

  3. MALIGNANT OBSTRUCTIVE JAUNDICE: A STUDY OF INVESTIGATIVE PARAMETERS AND ITS OUTCOME

    Directory of Open Access Journals (Sweden)

    Tilakdas S. Shetty

    2016-08-01

    Full Text Available BACKGROUND Obstructive jaundice is a surgical condition that occurs when there is an obstruction to the passage of conjugated bilirubin from the liver cells to the intestine. This study has studied five clinical and nine laboratory parameters in patients presenting with malignant obstructive jaundice along with their radiological findings. By studying these parameters, the prognosis of patients with malignant obstructive jaundice and the best possible intervention could be predicted. AIM To study the various aetiopathological aspects associated with obstructive jaundice and investigative parameters of these patients thereby evaluating the prognosis. MATERIALS AND METHODS This observational study has been conducted in a tertiary institute by collecting data of 50 cases of malignant obstructive jaundice admitted to the surgical wards of BYL Nair Hospital from August 2011 to August 2014 with followup of 3 months to obtain mortality data. Male and female patients above 18 years and below 80 years of age with histologically proven malignant obstructive jaundice were included as part of this study. Data of retrospective cases were obtained from Medical Record section without disclosing the address or identification of the patient. RESULTS In this study, a total of 50 cases of histologically proven malignant obstructive jaundice were evaluated. 50 patients were studied out of which 33 were male and 17 were female. Majority of the patients were in the age group of 61-70 years i.e. 21 of them. 11 patients were between 41-50 years of age, 10 were less than 40 years of age and 8 were between 51-60 years. The most common presentation of the patients was with yellowish discolouration of sclera and urine (YDS/YDU seen in 44 patients followed by pruritus seen in 38 patients. Dilated Common Bile Duct with/without pancreatic duct dilatation was the most common finding on sonography followed by a mass seen in the head of the pancreas. Moderately differentiated

  4. Novel methods for tendon investigations

    DEFF Research Database (Denmark)

    Kjær, Michael; Langberg, Henning; Bojsen-Møller, J.

    2008-01-01

    Purpose. Tendon structures have been studied for decades, but over the last decade, methodological development and renewed interest for metabolic, circulatory and tissue protein turnover in tendon tissue has resulted in a rising amount of investigations. Method. This paper will detail the various...... modern investigative techniques available to study tendons. Results. There are a variety of investigative methods available to study the correlations between mechanics and biology in tendons. Conclusion. The available methodologies not only allow for potential insight into physiological...... and pathophysiological mechanisms in tendon tissue, but also, to some extent, allow for more elaborate studies of the intact human tendon. Read More: http://informahealthcare.com/doi/full/10.1080/09638280701785403...

  5. 77 FR 75439 - Guidances for Industry and Investigators on Safety Reporting Requirements for Investigational New...

    Science.gov (United States)

    2012-12-20

    ...] Guidances for Industry and Investigators on Safety Reporting Requirements for Investigational New Drug Applications and Bioavailability/Bioequivalence Studies, and a Small Entity Compliance Guide; Availability... Reporting Requirements for INDs and BA/BE Studies'' and ``Safety Reporting Requirements for INDs and BA/BE...

  6. A Study for Visual Realism of Designed Pictures on Computer Screens by Investigation and Brain-Wave Analyses.

    Science.gov (United States)

    Wang, Lan-Ting; Lee, Kun-Chou

    2016-08-01

    In this article, the visual realism of designed pictures on computer screens is studied by investigation and brain-wave analyses. The practical electroencephalogram (EEG) measurement is always time-varying and fluctuating so that conventional statistical techniques are not adequate for analyses. This study proposes a new scheme based on "fingerprinting" to analyze the EEG. Fingerprinting is a technique of probabilistic pattern recognition used in electrical engineering, very like the identification of human fingerprinting in a criminal investigation. The goal of this study was to assess whether subjective preference for pictures could be manifested physiologically by EEG fingerprinting analyses. The most important advantage of the fingerprinting technique is that it does not require accurate measurement. Instead, it uses probabilistic classification. Participants' preference for pictures can be assessed using fingerprinting analyses of physiological EEG measurements. © The Author(s) 2016.

  7. Investigating Parents' Attitudes towards Digital Technology Use in Early Childhood: A Case Study from Croatia

    Science.gov (United States)

    Mikelic Preradovic, Nives; Lešin, Gordana; Šagud, Mirjana

    2016-01-01

    The aim of this study is to investigate perceptions of parents in Croatia towards advantages and disadvantages of computer use in general as well as their children's computer use and to reveal parents' concerns and opinions about digital technology (DT) education in kindergarten. The paper reports on research findings from one of the large public…

  8. Numerical Study of Condensation Heat Exchanger Design in a Subcooled Pool: Correlation Investigation

    International Nuclear Information System (INIS)

    Lee, Hee Joon; Ju, Yun Jae; Kang, Han Ok; Lee, Tae Ho; Park, Cheon Tae

    2012-01-01

    Generally the condensation heat exchanger has higher heat transfer coefficient compared to the single phase heat exchanger, so has been widely applied to the cooling systems of energy plant. Recently vertical or horizontal type condensation heat exchangers are being studied for the application to secondary passive cooling system of nuclear plants. Lee and Lee investigated the existing condensation correlation to the experiment for heat exchanger in saturated pool. They concluded Traviss' correlation showed most satisfactory results for the heat transfer coefficient and mass flow rate in a saturated water pool. In this study, a thermal sizing program of vertical condensation heat exchanger to design, TSCON(Thermal Sizing of CONdenser) was validated with the existing experimental data of condensation heat exchanger in a subcooled pool for pure steam condensation

  9. Investigation of the potential of wind energy applications in the Sct. Petersburg region. Pre-feasibility study report. Phase 1

    International Nuclear Information System (INIS)

    1995-11-01

    It was proposed to initiate an investigation and, if found to be viable, a feasibility study of the possibilities for partly substituting and supplementing the existing nuclear and fossil fuel based energy supply of the St. Petersburg region with environmentally benign wind energy. The feasibility study is expected to lead to one or more pilot projects. The proposal outlines a three-phased project including an investigation, a feasibility study and a full scale demonstration of wind energy in this region. A 4th phase is envisaged, and this will include the large scale introduction of wind energy applications using national and international financing and resulting in increased local production. The report covers the first phase, the investigation which includes data acquisition and desk studies. It is shown that technically exploitable wind potential exists in the St. Petersburg region, that local production of wind turbine equipment will reduce wind turbine costs due to decreased transport costs and lower local salaries, that suitable sites for the demonstration of both grid-connected wind farms and wind-diesel systems have been preliminarily identified and that the demonstration plants investigated have exhibited reasonable economic parameters - IRR in the range of 9 - 15%. But a feasibility study phase (2) including engineering and economic analyses must be carried out in order to reach the necessary detailed understanding of the technical and economic implications of full scale demonstration projects. (EG)

  10. Synthesis, X-ray crystallography, thermal studies, spectroscopic and electrochemistry investigations of uranyl Schiff base complexes.

    Science.gov (United States)

    Asadi, Zahra; Shorkaei, Mohammad Ranjkesh

    2013-03-15

    Some tetradentate salen type Schiff bases and their uranyl complexes were synthesized and characterized by UV-Vis, NMR, IR, TG, C.H.N. and X-ray crystallographic studies. From these investigations it is confirmed that a solvent molecule occupied the fifth position of the equatorial plane of the distorted pentagonal bipyramidal structure. Also, the kinetics of complex decomposition by using thermo gravimetric methods (TG) was studied. The thermal decomposition reactions are first order for the studied complexes. To examine the properties of uranyl complexes according to the substitutional groups, we have carried out the electrochemical studies. The electrochemical reactions of uranyl Schiff base complexes in acetonitrile were reversible. Copyright © 2012 Elsevier B.V. All rights reserved.

  11. Case study: Investigating the causes of temperature breaks in South African summer fruit export cold chains

    CSIR Research Space (South Africa)

    Goedhals-Gerber, LL

    2016-08-01

    Full Text Available This study investigated the causes and extent of temperature breaks in the South African summer fruit export cold chain from the pack house to the vessel. Numerous causes of temperature breaks throughout the cold chain were found, resulting in many...

  12. Non-invasive in-situ investigations versus micro-sampling: a comparative study on a Renoirs painting

    International Nuclear Information System (INIS)

    Miliani, C.; Sgamellotti, A.; Universita degli Studi di Perugia . Centro di Eccellenza SMAArt; Scientific Methodologies applied to Archaeology and Art)

    2007-01-01

    In this paper, a multi-technique in-situ non-invasive approach has been followed for the study of the materials used for a painting by Pierre-Auguste Renoir, ''A woman at her toilette''. The study was carried out using five portable spectroscopic techniques, namely X-ray fluorescence, mid-infrared reflectance spectroscopy, near infrared reflectance spectroscopy, and UV-Vis spectroscopy in absorption and emission. The painting was selected as a case study because it was examined in advance of the current investigation using conventional micro-sampling techniques. This provided the opportunity to evaluate potential and limitations of the non-invasive approach to the complex case of the modern painting. (orig.)

  13. Measuring perceived exercise capability and investigating its relationship with childhood obesity: a feasibility study.

    Science.gov (United States)

    Taylor, M J; Arriscado, D; Vlaev, I; Taylor, D; Gately, P; Darzi, A

    2016-01-01

    According to the COM-B ('Capability', 'Opportunity', 'Motivation' and 'Behaviour') model of behaviour, three factors are essential for behaviour to occur: capability, opportunity and motivation. Obese children are less likely to feel capable of exercising. The implementation of a new methodological approach to investigate the relationship between perceived exercise capability (PEC) and childhood obesity was conducted, which involved creating a new instrument, and demonstrating how it can be used to measure obesity intervention outcomes. A questionnaire aiming to measure perceived exercise capability, opportunity and motivation was systematically constructed using the COM-B model and administered to 71 obese children (aged 9-17 years (12.24±0.2.01), body mass index (BMI) standard deviation scores (SDS) 2.80±0.660) at a weight-management camp in northern England. Scale validity and reliability was assessed. Relationships between PEC, as measured by the questionnaire, and BMI SDS were investigated for the children at the weight-management camp, and for 45 Spanish schoolchildren (aged 9-13 years, (10.52±1.23), BMI SDS 0.80±0.99). A pilot study, demonstrating how the questionnaire can be used to measure the effectiveness of an intervention aiming to bring about improved PEC for weight-management camp attendees, was conducted. No participants withdrew from these studies. The questionnaire domain (exercise capability, opportunity and motivation) composite scales were found to have adequate internal consistency (a=0.712-0.796) and construct validity (χ(2)/degrees of freedom=1.55, root mean square error of approximation=0.072, comparative fit index=0.92). Linear regression revealed that low PEC was associated with higher baseline BMI SDS for both UK (b=-0.289, P=0.010) and Spanish (b=-0.446, P=0.047) participants. Pilot study findings provide preliminary evidence for PEC improvements through intervention being achievable, and measurable using the questionnaire

  14. Investigation of the paired-gear method in selectivity studies

    DEFF Research Database (Denmark)

    Sistiaga, Manu; Herrmann, Bent; Larsen, R.B.

    2009-01-01

    was repeated throughout the eight cases in this investigation. When using the paired-gear method, the distribution of the estimated L50 and SR is wider; the distribution of the estimated split parameter has a higher variability than the true split; the estimated mean L50 and SR can be biased; the estimated...... recommend that the methodology used to obtain selectivity estimates using the paired-gear method be reviewed....

  15. Remedial investigation/feasibility study of the Clinch River/Poplar Creek operable unit. Volume 1, main text

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    This document is the combined Remedial Investigation/Feasibility Study (RI/FS) Report for the Clinch River/Poplar Creek Operable Unit (CR/PC OU), an off-site OU associated with environmental restoration activities at the U.S. Department of Energy (DOE) Oak Ridge Reservation (ORR). As a result of past, present, and potential future releases of hazardous substances into the environment, the ORR was placed on the National Priorities List in December 1989 (54 FR 48184). Sites on this list must be investigated for possible remedial action, as required by the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA, 42 U.S.C. 9601, et seq.). This report documents the findings of the remedial investigation of this OU and the feasibility of potential remedial action alternatives. These studies are authorized by Sect. 117 of CERCLA and were conducted in accordance with the requirements of the National Contingency Plan (40 CFR Part 300). DOE, the U.S. Environmental Protection Agency (EPA), and the Tennessee Department of Environment and Conservation (TDEC) have entered into a Federal Facility Agreement (FFA), as authorized by Sect. 120 of CERCLA and Sects. 3008(h) and 6001 of the Resource Conservation and Recovery Act (RCRA) (42 U.S.C. 6901, et seq.). The purpose of this agreement is to ensure a coordinated and effective response for all environmental restoration activities occurring at the ORR. In addition to other responsibilities, the FFA parties mutually define the OU boundaries, set remediation priorities, establish remedial investigation priorities and strategies, and identify and select remedial actions. A copy of this FFA is available from the DOE Information Resource Center in Oak Ridge, Tennessee.

  16. Remedial investigation/feasibility study of the Clinch River/Poplar Creek operable unit. Volume 1, main text

    International Nuclear Information System (INIS)

    1996-03-01

    This document is the combined Remedial Investigation/Feasibility Study (RI/FS) Report for the Clinch River/Poplar Creek Operable Unit (CR/PC OU), an off-site OU associated with environmental restoration activities at the U.S. Department of Energy (DOE) Oak Ridge Reservation (ORR). As a result of past, present, and potential future releases of hazardous substances into the environment, the ORR was placed on the National Priorities List in December 1989 (54 FR 48184). Sites on this list must be investigated for possible remedial action, as required by the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA, 42 U.S.C. 9601, et seq.). This report documents the findings of the remedial investigation of this OU and the feasibility of potential remedial action alternatives. These studies are authorized by Sect. 117 of CERCLA and were conducted in accordance with the requirements of the National Contingency Plan (40 CFR Part 300). DOE, the U.S. Environmental Protection Agency (EPA), and the Tennessee Department of Environment and Conservation (TDEC) have entered into a Federal Facility Agreement (FFA), as authorized by Sect. 120 of CERCLA and Sects. 3008(h) and 6001 of the Resource Conservation and Recovery Act (RCRA) (42 U.S.C. 6901, et seq.). The purpose of this agreement is to ensure a coordinated and effective response for all environmental restoration activities occurring at the ORR. In addition to other responsibilities, the FFA parties mutually define the OU boundaries, set remediation priorities, establish remedial investigation priorities and strategies, and identify and select remedial actions. A copy of this FFA is available from the DOE Information Resource Center in Oak Ridge, Tennessee

  17. INSTRUMENTS AND METHODS OF INVESTIGATION: Positron annihilation spectroscopy in materials structure studies

    Science.gov (United States)

    Grafutin, Viktor I.; Prokop'ev, Evgenii P.

    2002-01-01

    A relatively new method of materials structure analysis — positron annihilation spectroscopy (PAS) — is reviewed. Measurements of positron lifetimes, the determination of positron 3γ- and 2γ-annihilation probabilities, and an investigation of the effects of different external factors on the fundamental characteristics of annihilation constitute the basis for this promising method. The ways in which the positron annihilation process operates in ionic crystals, semiconductors, metals and some condensed matter systems are analyzed. The scope of PAS is described and its prospects for the study of the electronic and defect structures are discussed. The applications of positron annihilation spectroscopy in radiation physics and chemistry of various substances as well as in physics and chemistry of solutions are exemplified.

  18. European Prospective Investigation into Cancer and Nutrition (EPIC) calibration study: rationale, design and population characteristics

    DEFF Research Database (Denmark)

    Slimani, N.; Kaaks, R.; Ferrari, P.

    2002-01-01

    The European Prospective Investigation into Cancer and Nutrition (EPIC), which covers a large cohort of half a million men and women from 23 European centres in 10 Western European countries, was designed to study the relationship between diet and the risk of chronic diseases, particularly cancer......, a calibration approach was developed. This approach involved an additional dietary assessment common across study populations to re-express individual dietary intakes according to the same reference scale. A single 24-hour diet recall was therefore collected, as the EPIC reference calibration method, from...... in a large multi-centre European study. These studies showed that, despite certain inherent methodological and logistic constraints, a study design such as this one works relatively well in practice. The average response in the calibration study was 78.3% and ranged from 46.5% to 92.5%. The calibration...

  19. An Investigation of Sustainable Power Generation from Oil Palm Biomass: A Case Study in Sarawak

    Directory of Open Access Journals (Sweden)

    Nasrin Aghamohammadi

    2016-04-01

    Full Text Available Sarawak is the largest state in Malaysia, with 22% of the nation's oil palm plantation area, making it the second largest contributor to palm biomass production. Despite the enormous amount of palm biomass in the state, the use of biomass as fuel for power generation remains low. This study is designed to investigate the sustainability of power generation from palm biomass specifically in Sarawak by conducting a survey among the palm oil mill developers. To conduct this investigation, several key sustainability factors were identified: the security of the biomass supply, the efficiency of conversion technology, the existing network system, challenges and future prospects for power generation from palm biomass. These factors were assessed through a set of questionnaires. The returned questionnaires were then analysed using statistical tools. The results of this study demonstrate that Sarawak has biomass in abundance, and that it is ready to be exploited for large scale power generation. The key challenge to achieving the renewable energy target is the inadequate grid infrastructure that inhibits palm oil developers from benefiting from the Feed-in-Tariff payment scheme. One way forward, a strategic partnership between government and industrial players, offers a promising outcome, depending on an economic feasibility study. The decentralization of electricity generation to support rural electrification is another feasible alternative for renewable energy development in the state.

  20. Is knowledge translation adequate? A quality assurance study of staging investigations in early stage breast cancer patients.

    Science.gov (United States)

    Han, Dolly; Hogeveen, Sophie; Sweet Goldstein, Miriam; George, Ralph; Brezden-Masley, Christine; Hoch, Jeffrey; Haq, Rashida; Simmons, Christine E

    2012-02-01

    After primary surgery, patients diagnosed with early stage breast cancer undergo radiological investigations based on pathologic stage of disease to rule out distant metastases. Published guidelines can aid clinicians in determining which tests are appropriate based on stage of disease. We wished to assess the consistency of radiological staging in an academic community oncology setting with standard guidelines and to determine the overall impact of non-adherence to these guidelines. A retrospective cohort study was conducted for new breast cancer patients seen at a single institution between January 2009 and April 2010. Patients were included if initial diagnosis and primary surgery was at this institution. Pathologic stage and radiological tests completed were recorded. A literature review was performed and the results were compared with those from this study to determine overall adherence rates. Subsequently, a cost analysis was performed to determine the financial impact at this centre. 231 patients met eligibility criteria for inclusion in this study. A large proportion of patients were over-staged with 129 patients (55%) undergoing unnecessary investigations according to guidelines. Specifically, 59% of stage I patients and 58% of stage II patients were over-investigated. Distant metastases at the time of diagnosis were found in three patients, all of whom had stage III disease (1.3%). The literature reviewed revealed similar non-adherence rates in other centres. The estimated cost of such non-adherence is in the range of $78 (CDN) per new early stage breast cancer patient seen at this centre. This oncology centre has a low adherence to practice guidelines for staging investigations in breast cancer patients, with 55% of patients undergoing unnecessary tests. Very few patients had metastases at diagnosis, and all had pathological stage III disease. Efforts may need to focus on improving knowledge translation across clinical oncology settings to increase

  1. Correlates of joint child protection and police child sexual abuse investigations: results from the Canadian Incidence Study of Reported Child Abuse and Neglect-2008

    Directory of Open Access Journals (Sweden)

    L. Tonmyr

    2015-01-01

    Full Text Available Introduction: Our study examines the frequency of joint investigations by child protection workers and the police in sexual abuse investigations compared to other maltreatment types and the association of child-, caregiver-, maltreatment- and investigation-related characteristics in joint investigations, focussing specifically on investigations involving sexual abuse. Methods: We analyzed data from the Canadian Incidence Study of Reported Child Abuse and Neglect-2008 using logistic regression. Results: The data suggest that sexual abuse (55%, and then physical abuse, neglect and emotional maltreatment, are most often co-investigated. Substantiation of maltreatment, severity of maltreatment, placement in out-of-home care, child welfare court involvement and referral of a family member to specialized services was more likely when the police were involved in an investigation. Conclusion: This study adds to the limited information on correlates of joint child protection agency and police investigations. Further research is needed to determine the effectiveness of these joint investigations.

  2. Remedial investigation/feasibility study report for Lower Watts Bar Reservoir Operable Unit

    International Nuclear Information System (INIS)

    1995-03-01

    This document is the combined Remedial Investigation and Feasibility Study Report for the lower Watts Bar Reservoir (LWBR) Operable Unit (OU). The LWBR is located in Roane, Rhea, and Meigs counties, Tennessee, and consists of Watts Bar Reservoir downstream of the Clinch river. This area has received hazardous substances released over a period of 50 years from the US Department of Energy's Oak Ridge Reservation (ORR), a National Priority List site established under the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA). As required by this law, the ORR and all off-site areas that have received contaminants, including LWBR, must be investigated to determine the risk to human health and the environment resulting from these releases, the need for any remedial action to reduce these risks, and the remedial actions that are most feasible for implementation in this OU. Contaminants from the ORR are primarily transported to the LWBR via the Clinch River. There is little data regarding the quantities of most contaminants potentially released from the ORR to the Clinch River, particularly for the early years of ORR operations. Estimates of the quantities released during this period are available for most radionuclides and some inorganic contaminants, indicating that releases 30 to 50 years ago were much higher than today. Since the early 1970s, the release of potential contaminants has been monitored for compliance with environmental law and reported in the annual environmental monitoring reports for the ORR

  3. Remedial investigation/feasibility study report for Lower Watts Bar Reservoir Operable Unit

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-03-01

    This document is the combined Remedial Investigation and Feasibility Study Report for the lower Watts Bar Reservoir (LWBR) Operable Unit (OU). The LWBR is located in Roane, Rhea, and Meigs counties, Tennessee, and consists of Watts Bar Reservoir downstream of the Clinch river. This area has received hazardous substances released over a period of 50 years from the US Department of Energy`s Oak Ridge Reservation (ORR), a National Priority List site established under the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA). As required by this law, the ORR and all off-site areas that have received contaminants, including LWBR, must be investigated to determine the risk to human health and the environment resulting from these releases, the need for any remedial action to reduce these risks, and the remedial actions that are most feasible for implementation in this OU. Contaminants from the ORR are primarily transported to the LWBR via the Clinch River. There is little data regarding the quantities of most contaminants potentially released from the ORR to the Clinch River, particularly for the early years of ORR operations. Estimates of the quantities released during this period are available for most radionuclides and some inorganic contaminants, indicating that releases 30 to 50 years ago were much higher than today. Since the early 1970s, the release of potential contaminants has been monitored for compliance with environmental law and reported in the annual environmental monitoring reports for the ORR.

  4. New Diethyl Ammonium Salt of Thiobarbituric Acid Derivative: Synthesis, Molecular Structure Investigations and Docking Studies

    Directory of Open Access Journals (Sweden)

    Assem Barakat

    2015-11-01

    Full Text Available The synthesis of the new diethyl ammonium salt of diethylammonium(E-5-(1,5-bis(4-fluorophenyl-3-oxopent-4-en-1-yl-1,3-diethyl-4,6-dioxo-2-thioxohexaydropyrimidin-5-ide 3 via a regioselective Michael addition of N,N-diethylthiobarbituric acid 1 to dienone 2 is described. In 3, the carboanion of the thiobarbituric moiety is stabilized by the strong intramolecular electron delocalization with the adjacent carbonyl groups and so the reaction proceeds without any cyclization. The molecular structure investigations of 3 were determined by single-crystal X-ray diffraction as well as DFT computations. The theoretically calculated (DFT/B3LYP geometry agrees well with the crystallographic data. The effect of fluorine replacement by chlorine atoms on the molecular structure aspects were investigated using DFT methods. Calculated electronic spectra showed a bathochromic shift of the π-π* transition when fluorine is replaced by chlorine. Charge decomposition analyses were performed to study possible interaction between the different fragments in the studied systems. Molecular docking simulations examining the inhibitory nature of the compound show an anti-diabetic activity with Pa (probability of activity value of 0.229.

  5. Investigating shape and space in mathematics: A case study | Kotze ...

    African Journals Online (AJOL)

    Evidence was obtained regarding mathematics teachers' and mathematics learners' knowledge of space and shape. Problems experienced in concept formation in geometry were investigated and analysed. An account is provided of how teachers and learners responded to problems related to space and shape.

  6. Investigating Instructional Design Management and Leadership Competencies--A Delphi Study

    Science.gov (United States)

    Gardner, Joel; Chongwony, Lewis; Washington, Tawana

    2018-01-01

    Research in instructional design and educational technology journals typically focuses on the theories, technologies, and processes related to practice of instructional design. There is little research emphasis, however, on leadership and management of instructional design in higher education. Investigating the competencies associated with…

  7. A Case Study Investigating Secondary Science Teachers' Perceptions of Science Literacy Instruction

    Science.gov (United States)

    Blackmon, Phyllis Ann

    This project study addressed the lack of inclusion of discipline literacy pedagogy in secondary classrooms in a rural school district in eastern North Carolina. Discipline literacy practices are recommended in the Common Core Standards for History/Social Studies, Science, and Technical Subjects. The district had implemented content area reading strategies across content areas, yet no significant progress in secondary students' reading abilities had been demonstrated in statewide or national assessments. The conceptual framework that drove this study was disciplinary literacy, founded by the literacy research of Shanahan, Shanahan, and Zygouris-Coe. Within a qualitative case study method, this investigation of 8 secondary science teachers' experiences teaching literacy during content instruction focused on practices of embedding science-specific reading strategies into lessons and factors that influence teachers' decisions to participate in professional development to advance their learning of discipline-specific literacy methods. Data were collected and triangulated using a focus group and 8 individual interviews. Data from both methods were analyzed into codes and categories that developed into emergent themes. Findings from the focus group and individual interviews revealed that the science teachers possessed limited knowledge of science-specific reading strategies; used random, general literacy practices; and had completed inadequate professional development on science-related topics. Positive change may occur if district leaders support teachers in expanding their knowledge and application of discipline literacy strategies through participation in discipline literacy-focused professional development. The study may provide educators and researchers a deeper understanding of disciplinary literacy and increase research on the topic.

  8. Investigating industrial investigation: examining the impact of a priori knowledge and tunnel vision education.

    Science.gov (United States)

    Maclean, Carla L; Brimacombe, C A Elizabeth; Lindsay, D Stephen

    2013-12-01

    The current study addressed tunnel vision in industrial incident investigation by experimentally testing how a priori information and a human bias (generated via the fundamental attribution error or correspondence bias) affected participants' investigative behavior as well as the effectiveness of a debiasing intervention. Undergraduates and professional investigators engaged in a simulated industrial investigation exercise. We found that participants' judgments were biased by knowledge about the safety history of either a worker or piece of equipment and that a human bias was evident in participants' decision making. However, bias was successfully reduced with "tunnel vision education." Professional investigators demonstrated a greater sophistication in their investigative decision making compared to undergraduates. The similarities and differences between these two populations are discussed. (c) 2013 APA, all rights reserved

  9. Site study plan for Playa investigations, Deaf Smith County, Texas: Salt Repository Project

    International Nuclear Information System (INIS)

    1987-01-01

    This plan defines the purpose and objectives of the Playa Investigation Study, presents a plan of work to provide the information necessary to resolve issues, and discusses the rationale for test method selection. The required information will be obtained from existing well drilling records, describing and testing of soil and rock samples recovered from project test holes, geophysical well logs, seismic surveys, and shallow test pits excavated at ground surface. There have been numerous, often conflicting, theories presented to explain the origin(s) of the playas of the Texas High Plains. The primary purpose of this study is to establish if existing playas and playa alignments are related to deeper subsurface structure, such as faulting or salt dissolution, the potential for future playa development, and the significance of existing and/or future playas on siting a repository in Deaf Smith County, Texas. 11 refs

  10. Studies and further needed investigations on radioactive contaminants in soil samples

    International Nuclear Information System (INIS)

    Belivermis, M.; Kilic, O.; Topcuoglu, S.; Cotuk, Y.; Kalayci, G.; Pestreli, D.

    2009-01-01

    Following the Chernobyl nuclear reactor accident, the radionuclides were deposited on the marine and terrestrial environments of Turkey and other countries as wet and / or dry fallout. It is well known that, the soil is the main reservoir at the terrestrial environment. The geographic distribution of the Chernobyl radionuclides per unit area is significantly different. Many countries have drawn radiation maps using the radionuclide data of the soil samples. The radioecological monitoring study in the soil samples are also investigated in the our country. However, the exist data is limited for whole region of Turkey. In general, the type study, that make, in uncultivated soil sample use of different soil layers (0-5, 5-10, 10-20, 20-30 cm). In our previous studies, the activity concentration of gamma emitting radionuclides were determined in soil samples (0-5 cm) from the Thrace (73 sites) and East and South Marmara (100 sites) regions. Moreover, the mean values of the annual effective dose equivalent were also calculated. In literature, numerous studies have been published concerning vertical migration of 1 37Cs in uncultivated soil samples use of different soil types. However, we have not enough data on this subject. On the other hand, we want to present a previously published data on the vertical distribution of 1 37Cs radionuclide in an uncultivated site in the eastern Black Sea region. It is well known that the determination of soil to plant transfer factors of radiocesium that take account all economically crops on the soil varieties is a need to support dose assessment or countermeasure studies. Previously published IAEA reports, we determined transfer factors for some crops of 1 37Cs radionuclides in cultivated soil samples (0-20 cm depth) in the eastern Black Sea region. At the same time, we have given a new project to IAEA for the determination of transfer factor of radiocesium from soil to some crops for Akkuyu Nuclear Power Plant site.

  11. Clinical Long-Term Outcome and Reinterventional Rate After Uterine Fibroid Embolization with Nonspherical Versus Spherical Polyvinyl Alcohol Particles

    Energy Technology Data Exchange (ETDEWEB)

    Duvnjak, Stevo, E-mail: stevo.duvnjak@rsyd.dk [Odense University Hospital, Department of Radiology (Denmark); Ravn, Pernille [Odense University Hospital, Department of Gynecology (Denmark); Green, Anders [Odense University Hospital, Odense Patient Data Explorative Network (Denmark); Andersen, Poul Erik [Odense University Hospital, Department of Radiology (Denmark)

    2016-02-15

    PurposeThis study was designed to evaluate the long-term clinical outcome and frequency of reinterventions in patients with uterine fibroids treated with embolization at a single center using polyvinyl alcohol microparticles.MethodsThe study included all patients with symptomatic uterine fibroids treated with uterine fibroid embolization (UFE) with spherical (s-PVA) and nonspherical (ns-PVA) polyvinyl alcohol microparticles during the period January 2001 to January 2011. Clinical success and secondary interventions were examined. Hospital records were reviewed during follow-up, and symptom-specific questionnaires were sent to all patients.ResultsIn total, 515 patients were treated with UFE and 350 patients (67 %) were available for long-term clinical follow-up. Median time of follow-up was 93 (range 76–120.2) months. Eighty-five patients (72 %) had no reinterventions during follow-up in the group embolized with ns-PVA compared with 134 patients (58 %) treated with s-PVA. Thirty-three patients (28 %) underwent secondary interventions in the ns-PVA group compared with 98 patients (42 %) in s-PVA group (χ{sup 2} test, p < 0.01).ConclusionsSpherical PVA particles 500–700 µm showed high reintervention rate at long-term follow-up, and almost one quarter of the patients underwent secondary interventions, suggesting that this type of particle is inappropriate for UFE.

  12. Remedial investigation/feasibility study for the David Witherspoon, Inc., 901 Site, Knoxville, Tennessee: Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-10-01

    This remedial investigation (RI)/feasibility study (FS) supports the selection of remedial actions for the David Witherspoon, Inc. 901 Maryville Pike Site in Knoxville, Tennessee. Operations at the site, used as a recycling center, have resulted in past, present, and potential future releases of hazardous substances in to the environment. This Site is a Tennessee Superfund site. A phased approach was planned to (1) gather existing data from previous investigations managed by the Tenn. Dept. of Environment and Conservation; (2) perform a preliminary RI, including risk assessments, and an FS with existing data to identify areas where remedial action may be necessary; (3) gather additional field data to adequately define the nature and extent of risk-based contaminants that present identifiable threats to human and/or ecological receptors; and (4) develop remedial action alternatives to reduce risks to acceptable levels.

  13. Remedial investigation/feasibility study for the David Witherspoon, Inc., 901 Site, Knoxville, Tennessee: Volume 1

    International Nuclear Information System (INIS)

    1996-10-01

    This remedial investigation (RI)/feasibility study (FS) supports the selection of remedial actions for the David Witherspoon, Inc. 901 Maryville Pike Site in Knoxville, Tennessee. Operations at the site, used as a recycling center, have resulted in past, present, and potential future releases of hazardous substances in to the environment. This Site is a Tennessee Superfund site. A phased approach was planned to (1) gather existing data from previous investigations managed by the Tenn. Dept. of Environment and Conservation; (2) perform a preliminary RI, including risk assessments, and an FS with existing data to identify areas where remedial action may be necessary; (3) gather additional field data to adequately define the nature and extent of risk-based contaminants that present identifiable threats to human and/or ecological receptors; and (4) develop remedial action alternatives to reduce risks to acceptable levels

  14. Case study: to investigate blogging as an e-learning tool in post-primary schools

    OpenAIRE

    Conroy, Patty

    2011-01-01

    non-peer-reviewed The purpose of this case study is to investigate blogging as an e-learning tool. The era of e-learning has truly arrived. Educators have at their hands many free e-learning tools. It can be no longer the case of how information technology can be incorporated into the classroom but how effective each e-learning tool is to us as educators. Educators need to embrace e-learning combined with traditional teaching methods in order to engage and motivate our students most of who...

  15. Investigating an Application of Speech-to-Text Recognition: A Study on Visual Attention and Learning Behaviour

    Science.gov (United States)

    Huang, Y-M.; Liu, C-J.; Shadiev, Rustam; Shen, M-H.; Hwang, W-Y.

    2015-01-01

    One major drawback of previous research on speech-to-text recognition (STR) is that most findings showing the effectiveness of STR for learning were based upon subjective evidence. Very few studies have used eye-tracking techniques to investigate visual attention of students on STR-generated text. Furthermore, not much attention was paid to…

  16. Investigation of soil potentially contaminated by monazite processing by-products: case study and suggestion for protocol

    International Nuclear Information System (INIS)

    Briquet, Claudia

    2006-01-01

    This work describes a characterization of soil potentially contaminated by monazite chemical processing residues. For case study it was selected a country area of Sao Paulo State, containing a monazite processing by-product depository. The main objective was to evaluate the soil contamination in an area of approximately 18,000 m 2 and esteem the total effective dose equivalent. During the development of this work, it was verified necessity of an investigation protocol, in order to standardize actions of regulatory authorities. A survey of the applicable legislation was carried out, as a tool to support decision making process. The methodology was based on the 'Manual de Gerenciamento de Areas Contaminadas' of CETESB (2001 a), a national document to guide studies of contaminated areas. It was also considered the 'Multi Agency Radiation Survey and Site Manual Investigation - MARSSIM' (2000), a U.S. government document that provides a nationally consensus approach to conduct investigations at potentially contaminated sites. The developed activities had been divided in three general stages: data-collecting and information on the place, identification of soil contamination and its distribution until the depth of 3 meters and evaluation of the associated dose. The evaluation of the radiological impact was carried out considering the worst-case use scenario (most restrictive future use), standing out that the final decision fits to the Brazilian National Nuclear Energy Commission - CNEN. CNEN's scope of responsibility includes determining the site release criteria and the cleanup necessity. (author)

  17. Studies of quaternary deposits in investigation trench OL-TK19 on the Olkiluoto study site, Eurajoki, SW Finland

    International Nuclear Information System (INIS)

    Huhta, P.

    2013-07-01

    The Quaternary deposits in investigation trench OL-TK19 were studied by the Geological Survey of Finland in October 2012. Samples for grain size determinations were taken from 3 vertical profiles, placed about 20-25 m apart along the trench. Two till units was sampled separately. The profiles extended from the soil surface down to bedrock. The samples were first dried in the laboratory after which they were sieved. In addition, the grain size distribution of the < 63 μm fraction was analyzed with the Sedigraph 5100 instrument. Sedimentological observations of the sampling profiles were documented in field by drawing them on a field observation form and the profiles were photographed using a digital camera. In addition, the excavated section was photographed along its whole length. The till cover in OL-TK19 consists of two parts. The surface layer of the till is oxidized, brownish grey sandy till, whereas the lower layer is unoxidized, grey silty till. Dark grey silty till as in the bottom of investigation trenches OL-TK13 and OL-TK14 was not found in this trench. The till layers in OL-TK19 was deposited in the last flow phase of the Weichselian continental ice. Bedrock striations indicate that the ice moved in a NW-SE direction. The till beds smooth bedrock topography. The tills showed no signs of disturbance related to bedrock movements. (orig.)

  18. High-risk populations identified in Childhood Cancer Survivor Study investigations: implications for risk-based surveillance.

    Science.gov (United States)

    Hudson, Melissa M; Mulrooney, Daniel A; Bowers, Daniel C; Sklar, Charles A; Green, Daniel M; Donaldson, Sarah S; Oeffinger, Kevin C; Neglia, Joseph P; Meadows, Anna T; Robison, Leslie L

    2009-05-10

    Childhood cancer survivors often experience complications related to cancer and its treatment that may adversely affect quality of life and increase the risk of premature death. The purpose of this manuscript is to review how data derived from Childhood Cancer Survivor Study (CCSS) investigations have facilitated identification of childhood cancer survivor populations at high risk for specific organ toxicity and secondary carcinogenesis and how this has informed clinical screening practices. Articles previously published that used the resource of the CCSS to identify risk factors for specific organ toxicity and subsequent cancers were reviewed and results summarized. CCSS investigations have characterized specific groups to be at highest risk of morbidity related to endocrine and reproductive dysfunction, pulmonary toxicity, cerebrovascular injury, neurologic and neurosensory sequelae, and subsequent neoplasms. Factors influencing risk for specific outcomes related to the individual survivor (eg, sex, race/ethnicity, age at diagnosis, attained age), sociodemographic status (eg, education, household income, health insurance) and cancer history (eg, diagnosis, treatment, time from diagnosis) have been consistently identified. These CCSS investigations that clarify risk for treatment complications related to specific treatment modalities, cumulative dose exposures, and sociodemographic factors identify profiles of survivors at high risk for cancer-related morbidity who deserve heightened surveillance to optimize outcomes after treatment for childhood cancer.

  19. Remedial investigation/feasibility study of the Clinch River/Poplar Creek operable unit. Volume 1: Main text

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-06-01

    This report presents the findings of an investigation into contamination of the Clinch River and Poplar Creek near the US Department of Energy`s (DOE`s) Oak Ridge Reservation (ORR) in eastern Tennessee. For more than 50 years, various hazardous and radioactive substances have been released to the environment as a result of operations and waste management activities at the ORR. In 1989, the ORR was placed on the National Priorities List (NPL), established and maintained under the federal Comprehensive environmental Response, Compensation, and Liability Act of 1980 (CERCLA). Under CERCLA, NPL sites must be investigated to determine the nature and extent of contamination at the site, assess the risk to human health and the environment posed by the site, and, if necessary, identify feasible remedial alternatives that could be used to clean the site and reduce risk. To facilitate the overall environmental restoration effort at the ORR, CERCLA activities are being implemented individually as distinct operable units (OUs). This document is the combined Remedial Investigation and Feasibility Study Report for the Clinch River/Poplar Creek OU.

  20. A Study Investigating the Perceived Service Quality Levels of Sport Center Members: A Kano Model Perspective

    Science.gov (United States)

    Yildiz, Kadir; Polat, Ercan; Güzel, Pinar

    2018-01-01

    The purpose of this study is to investigate sport center members' perceived service quality levels with a view to Kano customer expectations and requirements model. To that end, a descriptive approach and a correlational research design featuring survey method is adopted. Research group consists of 680 (300 women, 380 men) sport center members who…

  1. Black patients sustain vision loss while White and South Asian patients gain vision following delamination or segmentation surgery for tractional complications associated with proliferative diabetic retinopathy.

    Science.gov (United States)

    Mastropasqua, R; Luo, Y H-L; Cheah, Y S; Egan, C; Lewis, J J; da Cruz, L

    2017-10-01

    PurposeThis retrospective comparative case series aims to determine whether patient ethnicity (White versus South Asian versus Black) is related to the outcome of surgical treatment for traction complications of severe proliferative diabetic retinopathy (PDR).SettingMoorfields Eye Hospital London, UK.MethodsAll patients who underwent vitrectomy with, delamination and/or segmentation for PDR over a 5-year period (2009-2014) were reviewed retrospectively. Patients were divided into White, South Asian or Black groups, and their age, gender, HbA1C and type of diabetes were recorded. A total of 484 patients (253 White, 117 South Asian, 114 Black) were included. Twenty-one patients were excluded due to inadequate documentation.OutcomesLogMAR Visual acuity (converted from Snellen) (VA), was recorded pre-operatively and ~6 months post surgery (range 5-8 months). Surgical outcome was classified according to the type and duration of tamponade required post-operatively.ResultsPre-operative VA and HbA1C values were similar across all three ethnic groups (P=0.64 and 0.569, respectively). Change in VA (mean±SD) was 0.41±0.78, 0.14±0.76 and -0.26±0.57 in White, South Asian and Black patient groups respectively (PAsian patient groups.ConclusionsThis study demonstrates that Black patients on average lose vision following delamination surgery for traction complications of PDR while White and South Asian patients gain vision. The same group is also at higher risk of retaining silicone more than 6 months after surgery. This difference remains even when corrected for glycaemic control. The higher risk of visual loss and long-term retention of silicone oil in black patients requires further investigation. If these results are confirmed, surgeons should consider their patients' ethnicity before proceeding with surgical treatment of diabetic tractional detachment.

  2. Use of stable isotopes method in hydrological investigations with special reference to studies in Lower Maner Basin, Andhra Pradesh

    International Nuclear Information System (INIS)

    Kumar, B.; Athavale, R.N.; Sahay, K.S.N.

    1982-01-01

    The study of variations of stable isotope ratios in water is becoming increasingly important in hydrological investigations and is being widely used for: (i) characterizing water masses and indicating their origin, (ii) finding interconnection of water bodies, (iii) estimating leakages for reservoirs, (iv) water balances studies of lakes, (v) glaciological studies, etc. This paper briefly describes the principle of the method and details of isotope ratio measurement techniques used at the National Geophysical Research Institute, Hyderabad. Integrated geohydrological investigations comprising photogeological, hydrogeochemical, geophysical, nuclear and modelling studies have been carried out in the Lower Maner Basin, A.P., under an Indo-German collaboration project. As a part of this programme,, precipitation, surface and sub-surface water samples from the basin were analysed for their D:H and O 18 :O 16 ratios. The results of these measurements are presented and discussed. (author)

  3. Main nutrient patterns and colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition study

    NARCIS (Netherlands)

    Moskal, Aurélie; Freisling, Heinz; Byrnes, Graham; Assi, Nada; Fahey, Michael T.; Jenab, Mazda; Ferrari, Pietro; Tjønneland, Anne; Petersen, Kristina EN; Dahm, Christina C.; Hansen, Camilla Plambeck; Affret, Aurélie; Boutron-Ruault, Marie Christine; Cadeau, Claire; Kühn, Tilman; Katzke, Verena; Iqbal, Khalid; Boeing, Heiner; Trichopoulou, Antonia; Bamia, Christina; Naska, Androniki; Masala, Giovanna; de Magistris, Maria Santucci; Sieri, Sabina; Tumino, Rosario; Sacerdote, Carlotta; Peeters, Petra H.; Bueno-de-Mesquita, Bas H.; Engeset, Dagrun; Licaj, Idlir; Skeie, Guri; Ardanaz, Eva; Buckland, Genevieve; Castaño, José M Huerta; Quirós, José R.; Amiano, Pilar; Molina-Portillo, Elena; Winkvist, Anna; Myte, Robin; Ericson, Ulrika; Sonestedt, Emily; Perez-Cornago, Aurora; Wareham, Nick; Khaw, Kay Tee; Huybrechts, Inge; Tsilidis, Konstantinos K.; Ward, Heather; Gunter, Marc J.; Slimani, Nadia

    2016-01-01

    Background:Much of the current literature on diet–colorectal cancer (CRC) associations focused on studies of single foods/nutrients, whereas less is known about nutrient patterns. We investigated the association between major nutrient patterns and CRC risk in participants of the European Prospective

  4. Remedial investigation/feasibility study work plan for the 300-FF-1 operable unit, Hanford Site, Richland, Washington

    International Nuclear Information System (INIS)

    1990-03-01

    Over 1,400 waste facilities have been identified on the Hanford Site. Most of the waste facilities are located within geographic areas on the Hanford Site that are referred to as the 100, 200, 300, 400, and 1100 areas. The purpose of this work plan is to document the project scoping process and to outline all remedial investigation/feasibility study (RI/FS) activities, to determine the nature and extent of the threat presented by releases of hazardous substances from the operable unit, and to evaluate proposed remedies for such releases. The goal of the 300-FF-1 remedial investigation (RI) is to provide sufficient information needed to conduct the feasibility study (FS), by determining the nature and extent of the threat to public health and the environment posed by releases of hazardous substances from 300-FF-1, and the performance of specific remedial technologies. 62 refs., 28 figs., 48 tabs

  5. New Learning Method of a Lecture of ‘Machine Fabrication’ by Self-study with Investigation and Presentation Incorporated

    Science.gov (United States)

    Kasuga, Yukio

    A new teaching method was developed in learning ‘machine fabrication’ for the undergraduate students. This consists of a few times of lectures, grouping, decision of industrial products which each group wants to investigate, investigation work by library books and internet, arrangement of data containing characteristics of the products, employed materials and processing methods, presentation, discussions and revision followed by another presentation. This new method is derived from one of the Finland‧s way of primary school education. Their way of education is believed to have boosted up to the top ranking in PISA tests by OECD. After starting the new way of learning, students have fresh impressions on this lesson, especially for self-study, the way of investigation, collaborate work and presentation. Also, after four years of implementation, some improvements have been made including less use of internet, and determination of products and fabricating methods in advance which should be investigated. By this, students‧ lecture assessment shows further encouraging results.

  6. Investigation of heat transfer inside a PCM-air heat exchanger: a numerical parametric study

    Science.gov (United States)

    Herbinger, Florent; Bhouri, Maha; Groulx, Dominic

    2017-07-01

    In this paper, the use of PCMs for thermal storage of energy in HVAC applications was investigated by studying numerically the thermal performance of a PCM-air heat exchanger. The PCM used in this study was dodecanoic acid. A symmetric 3D model, incorporating conductive and convective heat transfer (air only) as well as laminar flow, was created in COMSOL Multiphysics 5.0. Simulations examined the dependence of the heat transfer rate on the temperature and velocity of the incoming air as well as the size of the channels in the heat exchanger. Results indicated that small channels size lead to a higher heat transfer rates. A similar trend was also obtained for high incoming air temperature, whereas the heat transfer rate was less sensitive to the incoming air velocity.

  7. Dietary flavonoid and lignan intake and gastric adenocarcinoma risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study123

    DEFF Research Database (Denmark)

    Zamora-Ros, Raul; Agudo, Antonio; Luján-Barroso, Leila

    2012-01-01

    Background: Several experimental studies have suggested potential anticarcinogenic effects of flavonoids, although epidemiologic evidence for the impact of dietary flavonoids on risk of gastric cancer (GC) is limited.Objective: We investigated the association between intake of dietary flavonoids...... and lignans and incident GC.Design: The study followed 477,312 subjects (29.8% men) aged 35–70 y from 10 European countries who participated in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Validated dietary questionnaires and lifestyle information were collected at baseline...

  8. Added value of a household-level study during an outbreak investigation of Salmonella serotype Saintpaul infections, New Mexico 2008.

    Science.gov (United States)

    Boore, A L; Jungk, J; Russo, E T; Redd, J T; Angulo, F J; Williams, I T; Cheek, J E; Gould, L H

    2013-10-01

    In 2008, nationwide investigations of a Salmonella serotype Saintpaul outbreak led first to consumer warnings for Roma and red round tomatoes, then later for jalapeño and serrano peppers. In New Mexico, where there were a large number of cases but no restaurant-based clusters, the NM Department of Health and the Indian Health Service participated with CDC in individual-level and household-level case-control studies of infections in New Mexico and the Navajo Nation. No food item was associated in the individual-level study. In the household-level study, households with an ill member were more likely to have had jalapeño peppers present during the exposure period and to have reported ever having serrano peppers in the household. This report illustrates the complexity of this investigation, the limitations of traditional individual-level case-control studies when vehicles of infection are ingredients or commonly eaten with other foods, and the added value of a household-level study.

  9. Using collaborative technology to enhance pre-service teachers' pedagogical content knowledge in Science

    Science.gov (United States)

    Donnelly, Dermot Francis; Hume, Anne

    2015-01-01

    Background:Supporting pre-service teacher (PT) collaboration as a means of professional learning is a challenging but essential task for effective practice. However, teacher placements or practicums in schools, which is common practice within teacher education programmes, can often isolate PTs from sharing their experiences with each other. Further, the articulation of effective pedagogical practices by high-quality teachers is limited, restricting PTs' ability to access such professional knowledge. Purpose:This study investigates how the introduction of a collaborative technology, a wiki, may enhance existing and new opportunities for pre-service teachers' (PTs) to develop pedagogical content knowledge (PCK). Sample:Seven PT chemistry teachers of varied backgrounds participated in this study. Design and method:The PTs were learning to collaboratively formulate and document their early topic-specific teaching knowledge using a pedagogical tool known as Content Representation (CoRe) design. Once scaffolded into this process, the PTs continued and extended this collaborative work online through the introduction of a wiki. Data were collected for qualitative analysis through the CoRe artefacts, a semi-structured focus group interview, and PTs' reflective essays about their collaborative experiences representing their teaching knowledge in CoRes through the wiki. Results:Data analysis highlighted that while wiki use showed some potential for collaborative representation when participants were not face-to-face, the PTs were hesitant in critiquing each other's work. As such, the online representations remained relatively static without face-to-face interaction. However, developing artefacts online was favoured over established practice and the access to artefacts of their peers on the wiki enhanced PTs' consideration for their own PCK. Conclusion:Wikis show some potential in the hosting of CoRes, but issues in simultaneous posting and lack of chat functionality may

  10. Prospect-EPIC Utrecht: study design and characteristics of the cohort population. European Prospective Investigation into Cancer and Nutrition.

    Science.gov (United States)

    Boker, L K; van Noord, P A; van der Schouw, Y T; Koot, N V; Bueno de Mesquita, H B; Riboli, E; Grobbee, D E; Peeters, P H

    2001-01-01

    The European Prospective Investigation into Cancer and Nutrition (EPIC), which has been established in order to investigate the relations between nutrition and cancer, was initiated in 1990 and involves 10 European countries with heterogeneous dietary patterns and differing cancer incidence rates. This manuscript presents the design, recruitment and baseline characteristics of the Prospect-EPIC cohort co-ordinated in Utrecht, The Netherlands. The cohort is based on volunteers recruited among women participating in a regional breast cancer screening program. It comprises of 17,357 subjects aged 50-69 years at enrolment from Utrecht and vicinity, who have consented to participate in the study and its follow-up. Each participant filled out a general questionnaire and a food frequency questionnaire. Participants were also physically examined and have donated a blood sample. Participation rate was 34.5%. Blood samples were donated by most participants (97.5%) and detailed informed consents were obtained from 87.4% of participants. Mean age at enrolment was 57 years. Anthropometric, lifestyle and morbidity characteristics of the cohort population did not differ largely from those of similar study populations in The Netherlands. Based on the Prospect-EPIC population, we intend to conduct prospective total cohort, nested case-control or case-cohort studies, in order to investigate relations between consumption of certain food groups or nutrients and chronic diseases, including hormone dependant cancers such as breast, colon, endometrial and ovary cancers.

  11. Legal and ethical obligations to conduct a clinical drug trial in Australia as an investigator initiated and sponsored study for an overseas pharmaceutical company.

    Science.gov (United States)

    Beran, Roy G

    2004-01-01

    Most multi-centre trials are both financed and sponsored by the pharmaceutical company involved. What follows will map the path adopted for an investigator initiated and sponsored study for a new indication of an established medication. The chief investigators of a company-sponsored, investigator-initiated, multi-centre, placebo-controlled study of an established medication, Pharmaceutical Benefit Scheme (PBS) listed for treatment of one condition but trialled in the management of another condition (trial of off-label use), were approached to submit a protocol to repeat the type of study with a different compound. The new study would test a different agent, also PBS listed, for the same condition as in the initial study and with the same off-licence application. The company would finance the study, provide the medication and matched placebo but only review the investigator-initiated protocol which would be sponsored by the principal investigator. This required the investigator to implement the trial, as would normally be done by the pharmaceutical company, yet also act as its principal investigator. The principal investigator, with colleagues and a Clinical Research Organisation (CRO), developed a protocol, adapted for the new agent, and submitted it for approval. Upon acceptance a contract was negotiated with the pharmaceutical company which had to overcome jurisdictional conflicts between common law and civil law legal systems. A CRO was contracted to undertake administrative functions which dictated special contractual agreements to overcome possible conflicts of interest for a sponsor/investigator to protect patient interests. There was need to find indemnification insurance with jurisdictional problems, co-investigators, ethics committee approvals and finance management as just some of the difficulties encountered. The paper will outline how these obstacles were overcome and how ethical and legal issues were respected through compromise. The ethical and legal

  12. Investigative Journalism, Corruption and Sustainable Development ...

    African Journals Online (AJOL)

    Investigative journalism is critical to the advancement and preservation of a country's democratic institutions and way of life and in helping to catalyse equitable development. Thus, the study focuses on how to curb corruption in Nigeria, through investigative journalism, so as to engender development at all levels. The study ...

  13. Punctuation and Implicit Prosody in Silent Reading: An ERP Study Investigating English Garden-Path Sentences.

    Science.gov (United States)

    Drury, John E; Baum, Shari R; Valeriote, Hope; Steinhauer, Karsten

    2016-01-01

    This study presents the first two ERP reading studies of comma-induced effects of covert (implicit) prosody on syntactic parsing decisions in English. The first experiment used a balanced 2 × 2 design in which the presence/absence of commas determined plausibility (e.g., John, said Mary, was the nicest boy at the party vs. John said Mary was the nicest boy at the party ). The second reading experiment replicated a previous auditory study investigating the role of overt prosodic boundaries in closure ambiguities (Pauker et al., 2011). In both experiments, commas reliably elicited CPS components and generally played a dominant role in determining parsing decisions in the face of input ambiguity. The combined set of findings provides further evidence supporting the claim that mechanisms subserving speech processing play an active role during silent reading.

  14. Investigating the Status of Tablet Computers and E-Books Use of Open Education Faculty Students: A Case Study

    Science.gov (United States)

    Koçak, Ömer; Yildirim, Önder; Kursun, Engin; Yildirim, Gürkan

    2016-01-01

    The increase in tablet computers and e-books use brings to mind the question of how users benefited from these technologies. In this sense, the present study investigated the status of students' tablet computers and e-books use and the reasons why students prefer to use and not use of tablet computers and e-books. Students' study habits while…

  15. Investigating the Place and Meaning of "Physical Education" to Preschool Children: Methodological Lessons from a Research Study

    Science.gov (United States)

    McEvilly, Nollaig

    2015-01-01

    Preschool physical education has not been extensively researched. Furthermore, research in physical activity and physical education rarely seeks young children's perspectives. The current paper focuses on one aspect of a post-structural study concerned with investigating the place and meaning of "physical education" to practitioners and…

  16. Lack of controlled studies investigating the risk of postpartum haemorrhage in cesarean delivery after prior use of oxytocin: a scoping review.

    Science.gov (United States)

    Bischoff, Karin; Nothacker, Monika; Lehane, Cornelius; Lang, Britta; Meerpohl, Joerg; Schmucker, Christine

    2017-11-29

    Postpartum haemorrhage (PPH) is a major cause of maternal mortality and morbidity worldwide. Experimental and clinical studies indicate that prolonged oxytocin exposure in the first or second stage of labour may be associated with impaired uterine contractility and an increased risk of atonic PPH. Therefore, particularly labouring women requiring cesarean delivery constitute a subset of patients that may exhibit an unpredictable response to oxytocin. We mapped the evidence for comparative studies investigating the hypothesis whether the risk for PPH is increased in women requiring cesarean section after induction or augmentation of labour. We performed a systematic literature search for clinical trials in Medline, Embase, Web of Science, and the Cochrane Library (May 2016). Additionally we searched for ongoing or unpublished trials in clinicaltrials.gov and the WHO registry platform. We identified a total of 36 controlled trials investigating the exogenous use of oxytocin in cesarean section. Data were extracted for study key characteristics and the current literature literature was described narratively. Our evidence map shows that the majority of studies investigating the outcome PPH focused on prophylactic oxytocin use compared to other uterotonic agents in the third stage of labour. Only 2 dose-response studies investigated the required oxytocin dose to prevent uterine atony after cesarean delivery for labour arrest. These studies support the hypotheses that labouring women exposed to exogenous oxytocin require a higher oxytocin dose after delivery than non-labouring women to prevent uterine atony after cesarean section. However, the study findings are flawed by limitations of the study design as well as the outcome selection. No clinical trial was identified that directly compared exogenous oxytocin versus no oxytocin application before intrapartum cesarean delivery. Despite some evidence from dose-response studies that the use of oxytocin may increase the

  17. The odd one out: Revisiting and investigating the gender imbalance in ICT study choices

    Directory of Open Access Journals (Sweden)

    Scott Morton

    Full Text Available For the past two decades there has been an imbalance between male and female students entering the Bachelor of Information Technology degree from high schools. The literature suggests that only one in six students entering higher education to study computer related degrees are female. It also suggests that occupational stereotyping can be linked to the decline in the number of females entering computing degree courses. This research is proposing to revisit and investigate why this is still prevalent in today\\'s society that has been brought up on technology and can see the benefits of good careers and good jobs.

  18. Investigation of Problems of Implementing Curriculum in Primary Schools in Somalia. African Studies in Curriculum Development & Evaluation.

    Science.gov (United States)

    Mohamed, Ibrahim Jeylani

    The aim of this study was to investigate the implementation of modern mathematics in the primary schools of Somalia. In particular, three concerns were addressed: (1) teachers' confidence and ability in teaching mathematics; (2) students' interest in mathematics; and (3) students' examination performance in mathematics. Subjects were 30 teachers…

  19. The use of marine geophysical methods in Geo-Engineering investigations of Dams/ Barrages - a case study of Kosi Barrage

    Digital Repository Service at National Institute of Oceanography (India)

    Vora, K.H.; Naidu, P.D.

    Geophysical Methods in Geo-Engineering Investigations of Dams/ Barrages - A Case Study of Kosi Barrage INTRODUCTION KH. Vora* P. Divakar Naidu* Dams and barrages are such civil engineering structures where foundation is submerged. The impounded water column... etc. Some other on the spot observations using pole and other elementary probing methods are in vogue. However, usually such investigations would provide only a generalised picture based on isolated data. Advent of high technology, developed over...

  20. Human Papillomavirus Antibodies and Future Risk of Anogenital Cancer : A Nested Case-Control Study in the European Prospective Investigation Into Cancer and Nutrition Study

    NARCIS (Netherlands)

    Kreimer, Aimee R.; Brennan, Paul; Kuhs, Krystle A. Lang; Waterboer, Tim; Clifford, Gary; Franceschi, Silvia; Michel, Angelika; Willhauck-Fleckenstein, Martina; Riboli, Elio; Castellsague, Xavier; Hildesheim, Allan; Fortner, Renee Turzanski; Kaaks, Rudolf; Palli, Domenico; Ljuslinder, Ingrid; Panico, Salvatore; Clavel-Chapelon, Francoise; Boutron-Ruault, Marie-Christine; Mesrine, Sylvie; Trichopoulou, Antonia; Lagiou, Pagona; Trichopoulos, Dimitrios; Peeters, Petra H.; Cross, Amanda J.; Bueno-de-Mesquita, H. Bas; Vineis, Paolo; Larranaga, Nerea; Pala, Valeria; Sanchez, Maria-Jose; Navarro, Carmen; Barricarte, Aurelio; Tumino, Rosario; Khaw, Kay-Tee; Wareham, Nicholas; Boeing, Heiner; Steffen, Annika; Travis, Ruth C.; Ramon Quiros, J.; Weiderpass, Elisabete; Pawlita, Michael; Johansson, Mattias

    2015-01-01

    Purpose Human papillomavirus (HPV) type 16 (HPV16) causes cancer at several anatomic sites. In the European Prospective Investigation Into Cancer and Nutrition study, HPV16 E6 seropositivity was present more than 10 years before oropharyngeal cancer diagnosis and was nearly absent in controls. The

  1. Investigating the Problems and Needs of Infertile Patients Referring to Assisted Reproduction Centers: A Review Study

    Directory of Open Access Journals (Sweden)

    Fahimeh Hasanbeigi

    2017-10-01

    Full Text Available Background: The provision of optimal care is the most important goal in nursing, the fulfillment of which requires the identification of clients’ problems and needs. However, based on the review of the literature, no review study has investigated the problems and needs of the infertile patients in Iran. Aim: The purpose of the present study was to investigate the problems and needs of the infertile patients referring to the assisted reproduction centers. Method: This review study was based on the traditional review procedure developed by Cronin et al., which entails five steps including: 1 choosing the topic of the review, 2 searching the manuscripts, 3 collecting, reading, and analyzing the texts, 4 writing the review, and 5 providing references. The articles published within 2003-2017 were searched in such valid databases as Google Scholar, Pub Med, Science Direct, Ovid, and Cochran. The inclusion criteria in this study were articles in Persian and English with the keywords referring to problems and needs of clients. Out of the 350 original articles, 31 cases were finally selected for this review study. Results: In general, the infertile patients’ problems were placed under four domains of mental-psychological, social, marital, and financial factors. The needs of the infertile individuals were grouped into six domains of physical, care, informational, financial, mental-psychological, and spiritual factors. Implications for Practice: The identification of the patients’ problems and needs can lead to the conceptualization of strategic points targeted toward the delivery of effective interventions facilitating the provision of patient-centered infertility care. This can enhance the quality of life and lower the levels of stress during the course of treatment.

  2. Alarming increase in the registration of degenerative rotator cuff-related lesions a nationwide epidemiological study investigating 244,519 patients

    DEFF Research Database (Denmark)

    Monrad, Nina; Ganestam, Ann; Kallemose, Thomas

    2018-01-01

    PURPOSE AND HYPOTHESIS: Shoulder lesions are common and a challenge to diagnose. They often result in significant disability for the patient and are an economic burden to society. From recent studies, an increasing incidence has been reported. The purpose of this study was to investigate and map ...

  3. Punctuation and Implicit Prosody in Silent Reading: An ERP Study Investigating English Garden-Path Sentences

    Science.gov (United States)

    Drury, John E.; Baum, Shari R.; Valeriote, Hope; Steinhauer, Karsten

    2016-01-01

    This study presents the first two ERP reading studies of comma-induced effects of covert (implicit) prosody on syntactic parsing decisions in English. The first experiment used a balanced 2 × 2 design in which the presence/absence of commas determined plausibility (e.g., John, said Mary, was the nicest boy at the party vs. John said Mary was the nicest boy at the party). The second reading experiment replicated a previous auditory study investigating the role of overt prosodic boundaries in closure ambiguities (Pauker et al., 2011). In both experiments, commas reliably elicited CPS components and generally played a dominant role in determining parsing decisions in the face of input ambiguity. The combined set of findings provides further evidence supporting the claim that mechanisms subserving speech processing play an active role during silent reading. PMID:27695428

  4. Punctuation and implicit prosody in silent reading: An ERP study investigating English garden-path sentences

    Directory of Open Access Journals (Sweden)

    John E. Drury

    2016-09-01

    Full Text Available This study presents the first two ERP reading studies of comma-induced effects of covert (implicit prosody on syntactic parsing decisions in English. The first experiment used a balanced 2 x 2 design in which the presence/absence of commas determined plausibility (e.g., John, said Mary, was the nicest boy at the party versus John said Mary was the nicest boy at the party. The second reading experiment replicated a previous auditory study investigating the role of overt prosodic boundaries in closure ambiguities (Pauker et al., 2011. In both experiments, commas reliably elicited CPS components and generally played a dominant role in determining parsing decisions in the face of input ambiguity. The combined set of findings provides further evidence supporting the claim that mechanisms subserving speech processing play an active role during silent reading.

  5. Investigating Parents' Attitudes towards Digital Technology Use in Early Childhood: A Case Study from Croatia

    OpenAIRE

    Nives MIKELIĆ PRERADOVIĆ; Gordana LEŠIN; Mirjana ŠAGUD

    2016-01-01

    The aim of this study is to investigate perceptions of parents in Croatia towards advantages and disadvantages of computer use in general as well as their children's computer use and to reveal parents' concerns and opinions about digital technology (DT) education in kindergarten. The paper reports on research findings from one of the large public kindergartens in the capital city of Croatia. A total of 152 parents of the children aged 3 to 7 enrolled at this early childhood education institut...

  6. An investigation of clinical studies suggests those with multiple objectives should have at least 90% power for each endpoint.

    NARCIS (Netherlands)

    Borm, G.F.; Houben, R.; Welsing, P.M.J.; Zielhuis, G.A.

    2006-01-01

    BACKGROUND AND OBJECTIVES: Many clinical studies have more than one objective, either formally or informally, but this is not usually taken into account in the determination of the sample size. We investigated the overall power of a study, that is, the probability that all the objectives will be

  7. Savannah River Site RCRA/CERCLA/NEPA integrated investigation case study

    International Nuclear Information System (INIS)

    Clark, D.R.; Thomas, R.; Wilson, M.P.

    1992-01-01

    The Savannah River Site (SRS) is a US Department of Energy facility placed on the Superfund National Priority List in 1989. Numerous past disposal facilities and contaminated areas are undergoing the integrated regulatory remediation process detailed in the draft SRS Federal Facility Agreement. This paper will discuss the integration of these requirements by highlighting the investigation of the D-Area Burning/Rubble Pits, a typical waste unit at SRS

  8. Time-course investigation of the gene expression profile during Fasciola hepatica infection: A microarray-based study

    Directory of Open Access Journals (Sweden)

    Jose Rojas-Caraballo

    2015-12-01

    Full Text Available Fasciolosis is listed as one of the most important neglected tropical diseases according with the World Health Organization and is also considered as a reemerging disease in the human beings. Despite there are several studies describing the immune response induced by Fasciola hepatica in the mammalian host, investigations aimed at identifying the expression profile of genes involved in inducing hepatic injury are currently scarce. Data presented here belong to a time-course investigation of the gene expression profile in the liver of BALB/c mice infected with F. hepatica metacercariae at 7 and 21 days after experimental infection. The data published here have been deposited in NCBI's Gene Expression Omnibus and are accessible through GEO Series accession number GSE69588, previously published by Rojas-Caraballo et al. (2015 in PLoS One [1].

  9. Investigating strengths and deficits to increase work engagement: A longitudinal study in the mining industry

    Directory of Open Access Journals (Sweden)

    Pule Mphahlele

    2018-02-01

    Full Text Available Orientation: The motivational process of the Job Demands-Resources (JD-R model indicates that job resources are the main predictors of work engagement. Previous research has found that the two job resources perceived organisational support (POS for strengths use and POS for deficit correction are also positively related to work engagement. However, the causal relationships between these variables have not been investigated longitudinally. Research purpose: To determine if POS for strengths use and POS for deficit correction are significant predictors of work engagement over time. Motivation for the study: In the literature, empirical evidence on the longitudinal relationships between work engagement and specific job resources, namely POS for strengths use and POS for deficit correction, is limited. Research design, approach and method: A longitudinal design was employed in this study. The first wave elicited a total of 376 responses, while the second wave had a total sample size of 79. A web-based survey was used to measure the constructs and to gather data at both points in time. Structural equation modelling was used to investigate the hypotheses. Main findings: The results indicated that both POS for strengths use and POS for deficit correction are positively related to work engagement in the short term. However, only POS for deficit correction significantly predicted work engagement over time. Practical and managerial implications: The results provide valuable insights to organisations by providing knowledge regarding which approach influences work engagement levels of their employees in the short and long term. Contribution or value-add: The study contributes to the limited research on what job resources predict work engagement over time.

  10. Remedial investigation/feasibility study report for lower Watts Bar Reservoir Operable Unit

    International Nuclear Information System (INIS)

    1994-08-01

    This document is the combined Remedial Investigation and Feasibility Study Report for the Lower Watts Bar Reservoir (LWBR) Operable Unit (OU). The LWBR is located in Roane, Rhea, and Meigs counties, Tennessee, and consists of Watts Bar Reservoir downstream of the Clinch River. This area has received hazardous substances released over a period of 50 years from the U.S. Department of Energy's Oak Ridge Reservation (ORR), a National Priority List site established under the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA). As required by this law, the ORR and all off-site areas that have received containments, including LWBR, must be investigated to determine the risk to human health and the environment resulting from these releases, the need for any remedial action to reduce these risks, and the remedial actions that are most feasible for implementation in this OU. Contaminants from the ORR are primarily transported to the LWBR via the Clinch River. Water-soluble contaminants released to ORR surface waters are rapidly diluted upon entering the Clinch River and then quickly transported downstream to the Tennessee River where further dilution occurs. Almost the entire quantity of these diluted contaminants rapidly flows through LWBR. In contrast, particle-associated contaminants tend to accumulate in the lower Clinch River and in LWBR in areas of sediment deposition. Those particle-associated contaminants that were released in peak quantities during the early years of ORR operations (e.g., mercury and 137 Cs) are buried under as much as 80 cm of cleaner sediment in LWBR. Certain contaminants, most notably polychlorinated biphenyls (PCBs), have accumulated in LWBR biota. The contamination of aquatic biota with PCBs is best documented for certain fish species and extends to reservoirs upstream of the ORR, indicating a contamination problem that is regional in scope and not specific to the ORR

  11. Site investigations. Investigation methods and general execution programme

    International Nuclear Information System (INIS)

    2001-01-01

    at least one deep chemistry-prioritized cored borehole, and start of long-term monitoring of chemical parameters in new selected sampling points. Fracture-filling mineral investigations are initiated during the final phase of the initial site investigation. The transport properties of the rock are estimated mainly on the basis of the hydrogeological and hydrogeochemical description, combined with generic, non-site-specific information. Furthermore, supplementary measurements of groundwater flow are performed in one of the first deep boreholes. In cases where mineralogy and/or groundwater chemistry differs significantly from the generic database, certain time-consuming laboratory investigations such as through diffusion measurements will be initiated. A large number of methods are used to investigate the geology of the site. They can be described in general terms under the headings: geophysics, surface geology, soil geology, bedrock geology, borehole investigations and geodetic measurements. The thermal properties of the rock are determined primarily on the basis of mineral composition and by means of laboratory studies of recovered rock cores. The determination of the transport properties of the rock is based on generic, non-site-specific data, combined with he hydrogeological and hydrogeochemical description of the rock. Laboratory measurements on drill cores and rock material are used to determine/verify sorption values and diffusivities. Diffusion tests and tracer tests in and between boreholes can be used to verify the reasonableness of estimated parameter values. The discipline surface ecosystems includes both the living environment, i.e. animals and plants, and their interactions with the non-living environment, e.g. climate and water. The characterization includes both hydrogeological and hydrogeochemical characterization of soil strata and surface waters and inventory/characterization of flora and fauna

  12. Investigating Research Streams of Conjoint Analysis: A Bibliometric Study

    Directory of Open Access Journals (Sweden)

    Thorsten Teichert

    2010-05-01

    Full Text Available Conjoint analysis (CA is one of the most important methods for preference elicitation. In this paper we investigate the intellectual structure within the conjoint analytical research community. Analyses based on single papers provide a method-based overview of streams of conjoint research. By using novel bibliometric techniques in this field we complement findings of existing reviews. We use co-citation and factor analysis of the most cited articles in SSCI to identify the most important articles and research streams. Seven research streams are revealed which are visualized by means of multidimensional scaling. Tables and graphics reveal the disciplinary affiliations of contributors to CA, the special structure within the classes as well as links between them.

  13. Remedial investigation/feasibility study for the David Witherspoon, Inc., 901 Site, Knoxville, Tennessee: Volume 2, Appendixes

    International Nuclear Information System (INIS)

    1996-10-01

    This document contains the appendixes for the remedial investigation and feasibility study for the David Witherspoon, Inc., 901 site in Knoxville, Tennessee. The following topics are covered in the appendixes: (A) David Witherspoon, Inc., 901 Site Historical Data, (B) Fieldwork Plans for the David Witherspoon, Inc., 901 Site, (C) Risk Assessment, (D) Remediation Technology Discussion, (E) Engineering Support Documentation, (F) Applicable or Relevant and Appropriate Requirements, and (G) Cost Estimate Documentation

  14. Remedial investigation/feasibility study for the David Witherspoon, Inc., 901 Site, Knoxville, Tennessee: Volume 2, Appendixes

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-10-01

    This document contains the appendixes for the remedial investigation and feasibility study for the David Witherspoon, Inc., 901 site in Knoxville, Tennessee. The following topics are covered in the appendixes: (A) David Witherspoon, Inc., 901 Site Historical Data, (B) Fieldwork Plans for the David Witherspoon, Inc., 901 Site, (C) Risk Assessment, (D) Remediation Technology Discussion, (E) Engineering Support Documentation, (F) Applicable or Relevant and Appropriate Requirements, and (G) Cost Estimate Documentation.

  15. How to achieve safe, high-quality clinical studies with non-Medicinal Investigational Products? A practical guideline by using intra-bronchial carbon nanoparticles as case study

    NARCIS (Netherlands)

    Berger, M; Kooyman, P.J.; Makkee, M.; van der Zee, J.S.; Sterk, P. J.; van Dijk, J.; Kemper, E. M.

    2016-01-01

    Background: Clinical studies investigating medicinal products need to comply with laws concerning good clinical practice (GCP) and good manufacturing practice (GMP) to guarantee the quality and safety of the product, to protect the health of the participating individual and to assure proper

  16. Arsenic Fate, Transport And Stability Study: Groundwater, Surface Water, Soil And Sediment Investigation At Fort Devens Superfund Site

    Science.gov (United States)

    A field investigation was conducted to examine the distribution of arsenic in groundwater, surface water, and sediments at the Fort Devens Superfund Site. The study area encompassed a portion of plow Shop Pond (Red Cove), which receives groundwater discharge from the aquifer und...

  17. Investigation on the characteristics of liquid wastes depending on their generation sources and study on optimum treatment method

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Sang Guk; Kim, Dong Chan; Shin, Dae Hyun; Son, Seung Geun; Roh, Nam Sun; Woo, Je Kyung [Korea Inst. of Energy Research, Taejon (Korea, Republic of)

    1995-12-01

    The major research contents conducted this year are as follows: (1) environmental regulation with respect to the treatment of the liquid waste in the U.S.A., (2) the present status of the generation and treatment of liquid wastes for large producers(>1,000 ton/year), (3) analysis for heating value element, heavy metal content, halogenated species on collected samples, (4) investigation on estimation method of energy recovery rate from liquid waste, (5) design of a lab. scale reactor which could be capable of conducting thermal decomposition test with small quantity of sample. In this study, present status of liquid waste generation and treatment is investigated, and thermal decomposition characteristics are studied using a lab. scale thermal reactor. The purpose of this research is to divide liquid waste into groups and to present best treatment method for their each group. (author). 24 refs., 21 figs., 23 tabs.

  18. Investigation of Wave Energy Converter Effects on Wave Fields: A Modeling Sensitivity Study in Monterey Bay CA.

    Energy Technology Data Exchange (ETDEWEB)

    Roberts, Jesse D.; Grace Chang; Jason Magalen; Craig Jones

    2014-08-01

    A n indust ry standard wave modeling tool was utilized to investigate model sensitivity to input parameters and wave energy converter ( WEC ) array deploym ent scenarios. Wave propagation was investigated d ownstream of the WECs to evaluate overall near - and far - field effects of WEC arrays. The sensitivity study illustrate d that b oth wave height and near - bottom orbital velocity we re subject to the largest pote ntial variations, each decreas ed in sensitivity as transmission coefficient increase d , as number and spacing of WEC devices decrease d , and as the deployment location move d offshore. Wave direction wa s affected consistently for all parameters and wave perio d was not affected (or negligibly affected) by varying model parameters or WEC configuration .

  19. Guest investigator program study: Physics of equatorial plasma bubbles

    Science.gov (United States)

    Tsunoda, Roland T.

    1994-01-01

    -shaped plasma bubbles. The second topic was pursued because the inability to predict the day-to-day occurrence of plasma bubbles indicated inadequate knowledge of the physics of plasma bubbles. An understanding of bubble formation requires an understanding of the roles of the various terms in the linearized growth rate of the collisional Rayleigh-Taylor instability. In our study, we examined electric-field perturbations found in SM-D EFI data and found that the seeding is more likely to be produced in the E region rather than the F region. The results of this investigation are presented in the Appendix of this report and will be submitted for publication in the Journal of Geophysical Research.

  20. How to achieve safe, high-quality clinical studies with non-Medicinal Investigational Products? A practical guideline by using intra-bronchial carbon nanoparticles as case study

    NARCIS (Netherlands)

    Berger, M.; Kooyman, P. J.; Makkee, M.; van der Zee, J. S.; Sterk, P. J.; van Dijk, J.; Kemper, E. M.

    2016-01-01

    Clinical studies investigating medicinal products need to comply with laws concerning good clinical practice (GCP) and good manufacturing practice (GMP) to guarantee the quality and safety of the product, to protect the health of the participating individual and to assure proper performance of the

  1. Remedial Investigation/Feasibility Study Work Plan for the 200-UP-1 Groundwater Operable Unit, Hanford Site, Richland, Washington

    International Nuclear Information System (INIS)

    1994-01-01

    This work plan identifies the objectives, tasks, and schedule for conducting a Remedial Investigation/Feasibility Study for the 200-UP-1 Groundwater Operable Unit in the southern portion of the 200 West Groundwater Aggregate Area of the Hanford Site. The 200-UP-1 Groundwater Operable Unit addresses contamination identified in the aquifer soils and groundwater within its boundary, as determined in the 200 West Groundwater Aggregate Area Management Study Report (AAMSR) (DOE/RL 1992b). The objectives of this work plan are to develop a program to investigate groundwater contaminants in the southern portion of the 200 West Groundwater Aggregate Area that were designated for Limited Field Investigations (LFIs) and to implement Interim Remedial Measures (IRMs) recommended in the 200 West Groundwater AAMSR. The purpose of an LFI is to evaluate high priority groundwater contaminants where existing data are insufficient to determine whether an IRM is warranted and collect sufficient data to justify and implement an IRM, if needed. A Qualitative Risk Assessment (QRA) will be performed as part of the LFI. The purpose of an IRM is to develop and implement activities, such as contaminant source removal and groundwater treatment, that will ameliorate some of the more severe potential risks of groundwater contaminants prior to the RI and baseline Risk Assessment (RA) to be conducted under the Final Remedy Selection (FRS) at a later date. This work plan addresses needs of a Treatability Study to support the design and implementation of an interim remedial action for the Uranium- 99 T c -Nitrate multi-contaminant IRM plume identified beneath U Plant

  2. A Study Investigating the Feasibility of Creating a Short Form of the WISC-R for Disabled Readers.

    Science.gov (United States)

    Brown, David M.; Otts, David A.

    The purpose of this study was to investigate the feasibility of creating a short form of the Wechsler Intelligence Scale for Children-Revised (WISC-R) for use in a clinical setting with disabled readers. The subjects were 100 clients ages six to sixteen of the Belser-Parton Reading Center at the University of Alabama whose files contained scores…

  3. An exploratory study investigating children's perceptions of dental behavioural management techniques.

    Science.gov (United States)

    Davies, E Bethan; Buchanan, Heather

    2013-07-01

    Behaviour management techniques (BMTs) are utilised by dentists to aid children's dental anxiety (DA). Children's perceptions of these have been underexplored, and their feedback could help inform paediatric dentistry. To explore children's acceptability and perceptions of dental communication and BMTs and to compare these by age, gender, and DA. A total of sixty-two 9- to 11-year-old school children participated in the study. Children's acceptability of BMTs was quantified using a newly developed Likert scale, alongside exploration of children's experiences and perceptions through interviews. anova and t-tests explored BMT acceptability ratings by age, gender, and DA. Thematic analysis was used to analyse interviews. Statistical analyses showed no effect of age, gender, or DA upon BMT acceptability. Children generally perceived the BMTs as acceptable or neutral; stop signals were the most acceptable, and voice control the least acceptable BMT. Beneficial experiences of distraction and positive reinforcement were common. Children described the positive nature of their dentist's communication and BMT utilisation. Dental anxiety did not affect children's perceptions of BMTs. Children were generally positive about dentist's communication and established BMTs. Children's coping styles may impact perceptions and effectiveness of BMTs and should be explored in future investigations. © 2012 John Wiley & Sons Ltd, BSPD and IAPD.

  4. A pilot study investigating the association between sleep and cognitive function among adolescents.

    Science.gov (United States)

    Ahmad, Shafiq; Bashir, Shahid

    2017-08-01

    To investigate the relationship between sleep and cognitive function among adolescent subjects in Riyadh. The sample consisted of 98 (44% female) subjects aged 10-16 years. Each participant filled in a well-structured pre-coded questionnaire regarding demographic data, including a sleep questionnaire; cognitive function was assessed using the Cambridge Neuropsychological Automated Battery (CANTAB). The cognitive function outcome variables were response times in the attention-switching task (AST) and the percentage of correct answers in the pattern recognition memory (PRM) task. There were significant differences in measures of AST-latency (p=0.005), AST-congruent (p=0.012), and AST-incongruent (p=0.009), while no significant difference was found in the PRM task score (p=0.336) within gender groups. There was a significant correlation between sleep and AST switching cost (0.277, p=0.006) and sleep and AST latency (0.188, p=0.063) across the group. This study showed that gender differences in cognitive function were significant in the group of adolescents. Additionally, this study shows that insufficient sleep can impair attention and accuracy in adolescents. Copyright © 2017 Elsevier B.V. All rights reserved.

  5. An Exploratory Study Investigating How and Why Managers Use Tablets to Support Managerial Decision-Making

    Directory of Open Access Journals (Sweden)

    Meng Xiao

    2017-11-01

    Full Text Available Managers are often mobile and a large proportion of their work is dealing with decisions. Although many managers currently use tablet computers in their work, there is little research on the use of tablets for managerial decision-support. This exploratory study aims to investigate the ways in which managers use tablets to support their decision-making and the reasons why they do so. Using Task-Technology Fit theory, semi-structured interviews were conducted with 20 managers, 17 of whom used tablets for their work-related decision-making. The study reveals managers’ tablet usage patterns in terms of location, tablet applications, decision activities and types. This study has also found that a range of tablet characteristics and decision-task characteristics affect managers’ use of tablets to support decision-making at work. This exploratory study contributes to both academia and industry by providing evidence on the tablet decision-support area, and affording organisations, tablet vendors and tablet application developers informative findings for further improvement in the provision of tablet-based decision support.

  6. Investigating audiences’ attitudes towards local radio programs: A case study of city of Esfahan

    Directory of Open Access Journals (Sweden)

    Faezeh Taghipour

    2013-02-01

    Full Text Available For almost a century, radio stations have been some primary sources for presenting arts, entertainment, news, etc. and the primary concern on many studies is to understand audience attitude on this media. This paper attempts to investigate audience attitude on radio programs broadcasted in city of Esfahan, Iran. The proposed study selects random sample of 600 out of 1,745,428 residence of this city where 345 people actively were listening to these programs, actively. All questions were designed in Likert scale and Cronbach alpha was 0.941, which was well above the desirable level and validated the survey. According our survey, the most popular part of radio programs was associated with news where 78.3% of the audiences were listening to these programs. According to our survey, audiences were mostly satisfied with family oriented programs and the mean score was 4.05. The other observation indicates that people have good attitude towards educational guidance programs (mean=3.37 and programs related to people and officials (mean=3.41. The results of Freedman test with Chi-Square value of 52.507 determines that there is meaningful difference among different components (mean difference = -0.23 and P-value =0.022. We have also performed an investigation to find out whether there is any difference between different components of this survey in terms of participants’ personal characteristics such as age, gender, educational background and job. Our survey only confirms the mean difference in terms of job specifications and other personal characteristics did not have any impact on people’s attitude. The other observation in our survey indicates that there is a difference between students and people with no job or housekeeper on their attitudes towards educational programs.

  7. Extended criteria and predictors in college admission: Exploring the structure of study success and investigating the validity of domain knowledge

    Directory of Open Access Journals (Sweden)

    OLGA KUNINA

    2007-06-01

    Full Text Available The utility of aptitude tests and intelligence measures in the prediction of the success in college is one of the empirically best supported results in ability research. However, the structure of the criterion “study success” has not been appropriately investigated so far. Moreover, it remains unclear which aspect of intelligence – fluid intelligence or crystallized intelligence – has the major impact on the prediction. In three studies we have investigated the dimensionality of the criterion achievements as well as the relative contributions of competing ability predictors. In the first study, the dimensionality of college grades was explored in a sample of 629 alumni. A measurement model with two correlated latent factors distinguishing undergraduate college grades on the one hand from graduate college grades on the other hand had the best fit to the data. In the second study, a group of 179 graduate students completed a Psychology knowledge test and provided available college grades in undergraduate studies. A model separating a general latent factor for Psychology knowledge from a nested method factor for college grades, and a second nested factor for “experimental orientation” had the best fit to the data. In the third study the predictive power of domain specific knowledge tests in Mathematics, English, and Biology was investigated. A sample of 387 undergraduate students in this prospective study additionally completed a compilation of fluid intelligence tests. The results of this study indicate as expected that: a ability measures are incrementally predictive over school grades in predicting exam grades; and b that knowledge tests from relevant domains were incrementally predictive over fluid intelligence. The results of these studies suggest that criteria for college admission tests deserve and warrant more attention, and that domain specific ability indicators can contribute to the predictive validity of established

  8. Numerical Study of Condensation Heat Exchanger Design in a Cooling jacket: Correlation Investigation

    International Nuclear Information System (INIS)

    Kim, Myoung Jun; Lee, Hee Joon; Kang, Han Ok; Lee, Tae Ho; Park, Cheon Tae

    2013-01-01

    In this study, condensing heat transfer correlation of TSCON is evaluated with the existing experimental data set to design condensation heat exchanger without noncondensable gas effect (pure steam condensation) in a cooling jacket. From the investigation of the existing condensation heat transfer correlation to the existing experimental data, the improved Shah's correlation showed most satisfactory result for the condensation heat transfer coefficient with experimental data of Khun in a cooling jacket, whereas the Shah's correlation with experimental data of Lee. Lee et al. reported the improved Shah correlation gave us the best predictor for the condensation heat transfer data of Kim and Henderson in a subcooled and saturated water pool. They suggested the improved Shah correlation should be adopted as condensation heat transfer module in TSCON(Thermal Sizing of CONdenser) to design condensation heat exchanger in secondary passive cooling system of nuclear plant

  9. Final report on neutron irradiation at low temperature to investigate plastic instability and a high temperature to study cavitation

    International Nuclear Information System (INIS)

    Singh, B.N.; Eldrup, M.; Golubov, S.I.; Edwards, D.J.; Jung, P.

    2005-01-01

    Effects of neutron irradiation on defect accumulation and physical and mechanical properties of pure iron and F82H and EUROFER 97 ferritic-martensitic steels have been investigated. Tensile specimens were neutron irradiated to a dose level of 0,23 dpa at 333 and 573 K. Electrical resistivity and tensile properties were measured both in the unirradiated and irradiated condition. Some additional specimens of pure iron were irradiated at 333 K to doses of 10-3, 10-2 and 10-1 dpa and tensile tested at 333 K. To investigate the effect of helium on cavity nucleation and growth, specimens of pure iron and EUROFER 97 were implanted with different amounts of helium at 323 K and subsequently neutron irradiated to doses of 10-3, 10-2 and 10-1 dpa at 323 K. Defect microstructures were investigated using positron annihilation spectroscopy (PAS) and transmission electron microscopy (TEM). Numerical calculations, based on the production bias model (PBM) were carried out to study the details of evolution of cavities with and without helium generation. The phenomena of dislocation decoration and raft formation, which are important for understanding radiation hardening and plastic flow localization, have been studied using the Kinetic Monte Carlo (KMC) code during a realistic dynamic irradiation of bcc iron at 300 K. Molecular dynamics (MD) simulations have been carried out to study the stress dependencies of dislocation velocity and drag coefficient for an edge dislocation decorated with small SIA loops.The present report describes both experimental procedure and calculational methodology employed in the present work. The main results of all these investigations, both experimental and theoretical, are highlighted with appropriate examples. Finally, a brief summary is given of the main results conclusions. (au)

  10. Reliability study of Piezoelectric Structures Dedicated to Energy Harvesting by the Way of Blocking Force Investigation

    International Nuclear Information System (INIS)

    Maaroufi, S; Parrain, F; Lefeuvre, E; Boutaud, B; Molin, R Dal

    2015-01-01

    In this paper we propose an approach to study the reliability of piezoelectric structures and more precisely energy harvesting micro-devices dedicated to autonomous active medical implants (new generation pacemakers). The structure under test is designed as a bimorph piezoelectric cantilever with a seismic mass at its tip. Good understanding of material aging and mechanical failure is critical for this kind of system. To study the reliability and durability of the piezoelectric part we propose to establish a new accelerated methodology and an associated test bench where the environment and stimuli can be precisely controlled over a wide period of time. This will allow the identification of potential failure modes and the study of their impacts by the way of direct mechanical investigation based on stiffness and blocking force measurements performed periodically. (paper)

  11. Reliability study of Piezoelectric Structures Dedicated to Energy Harvesting by the Way of Blocking Force Investigation

    Science.gov (United States)

    Maaroufi, S.; Parrain, F.; Lefeuvre, E.; Boutaud, B.; Dal Molin, R.

    2015-12-01

    In this paper we propose an approach to study the reliability of piezoelectric structures and more precisely energy harvesting micro-devices dedicated to autonomous active medical implants (new generation pacemakers). The structure under test is designed as a bimorph piezoelectric cantilever with a seismic mass at its tip. Good understanding of material aging and mechanical failure is critical for this kind of system. To study the reliability and durability of the piezoelectric part we propose to establish a new accelerated methodology and an associated test bench where the environment and stimuli can be precisely controlled over a wide period of time. This will allow the identification of potential failure modes and the study of their impacts by the way of direct mechanical investigation based on stiffness and blocking force measurements performed periodically.

  12. Attrition and bias in the MRC cognitive function and ageing study: an epidemiological investigation

    Directory of Open Access Journals (Sweden)

    Matthews Fiona E

    2004-04-01

    . However, these differences could also affect other investigations, particularly the estimates of incidence and longitudinal effects of health and psychiatric diseases, where the factors shown here to be associated with attrition are risk factors for the diseases. All longitudinal studies should investigate attrition and this may help with aspects of design and with the analysis of specific hypotheses.

  13. A Quasi-Experimental Study Investigating the Effect of Scent on Students' Memory of Multiplication Facts and Math Anxiety

    Science.gov (United States)

    Leap, Evelyn M.

    2013-01-01

    This quasi-experimental study was conducted with two fifth grade classrooms to investigate the effect of scent on students' acquisition and retention of multiplication facts and math anxiety. Forty participants received daily instruction for nine weeks, using a strategy-rich multiplication program called Factivation. Students in the Double Smencil…

  14. Evaluation of Effectiveness of Embolization in Pelvic Congestion Syndrome with the New Vascular Occlusion Device (ArtVentive EOS™): Preliminary Results

    International Nuclear Information System (INIS)

    Pyra, Krzysztof; Woźniak, Sławomir; Drelich-Zbroja, Anna; Wolski, Andrzej; Jargiełło, Tomasz

    2016-01-01

    PurposeThis study aimed to collect confirmatory data in support of the safety and efficiency of the ArtVentive EOS™ for the treatment of the pelvic congestion syndrome (PCS). This study was based on the OCCLUDE 1 Study Protocol approved by the Local Ethics Committee.Materials and MethodsA prospective study carried out in June and July 2014 included 12 women aged 21–48 years (mean 31 years) scheduled for PCS embolization using the ArtVentive EOS™. The inclusion criteria were clinical symptoms of PCS documented by transvaginal Doppler ultrasound and pelvic MRI. The pelvic pain was assessed by VAS score from 0 to 10 (0 represents lack of pain and 10 unbearable pain). A decrease in pelvic pain intensity based on the VAS was considered a clinical success.ResultsSuccessful embolization procedures with ArtVentive EOS™ were performed in 11 out of 12 patients. Nine patients underwent unilateral embolization of the left ovarian vein, and two had bilateral embolization of the ovarian veins. Complete ovarian vein occlusion confirmed by post deployment venography was achieved in all 11 patients. Procedures lasted from 19 to 45 min (average 28 min). Pain intensity decrease was observed in all 11 patients—a decrease of 5.6 points—from 7.3 pre-procedure to 1.6 post-embolization (standard deviation: 0.67). In one case, the left ovarian vein was injured by guide wire manipulation with contrast extravasation—not clinically significant.ConclusionsThe use of ArtVentive EOS™ for occlusion of the ovarian veins in PCS patients is safe and effective.

  15. Evaluation of Effectiveness of Embolization in Pelvic Congestion Syndrome with the New Vascular Occlusion Device (ArtVentive EOS™): Preliminary Results

    Energy Technology Data Exchange (ETDEWEB)

    Pyra, Krzysztof, E-mail: k.pyra@poczta.fm [Medical University of Lublin, Department of Interventional Radiology and Neuroradiology (Poland); Woźniak, Sławomir, E-mail: slavwo7572@gmail.com [Medical University of Lublin, III Gynecology Clinic (Poland); Drelich-Zbroja, Anna, E-mail: zbroanna@interia.pl; Wolski, Andrzej, E-mail: andrzej.s.wolski@gmail.com; Jargiełło, Tomasz, E-mail: tojarg@interia.pl [Medical University of Lublin, Department of Interventional Radiology and Neuroradiology (Poland)

    2016-08-15

    PurposeThis study aimed to collect confirmatory data in support of the safety and efficiency of the ArtVentive EOS™ for the treatment of the pelvic congestion syndrome (PCS). This study was based on the OCCLUDE 1 Study Protocol approved by the Local Ethics Committee.Materials and MethodsA prospective study carried out in June and July 2014 included 12 women aged 21–48 years (mean 31 years) scheduled for PCS embolization using the ArtVentive EOS™. The inclusion criteria were clinical symptoms of PCS documented by transvaginal Doppler ultrasound and pelvic MRI. The pelvic pain was assessed by VAS score from 0 to 10 (0 represents lack of pain and 10 unbearable pain). A decrease in pelvic pain intensity based on the VAS was considered a clinical success.ResultsSuccessful embolization procedures with ArtVentive EOS™ were performed in 11 out of 12 patients. Nine patients underwent unilateral embolization of the left ovarian vein, and two had bilateral embolization of the ovarian veins. Complete ovarian vein occlusion confirmed by post deployment venography was achieved in all 11 patients. Procedures lasted from 19 to 45 min (average 28 min). Pain intensity decrease was observed in all 11 patients—a decrease of 5.6 points—from 7.3 pre-procedure to 1.6 post-embolization (standard deviation: 0.67). In one case, the left ovarian vein was injured by guide wire manipulation with contrast extravasation—not clinically significant.ConclusionsThe use of ArtVentive EOS™ for occlusion of the ovarian veins in PCS patients is safe and effective.

  16. A study investigating patients' experience of hospital and home iontophoresis for hyperhidrosis.

    LENUS (Irish Health Repository)

    McAleer, Maeve Aine

    2014-08-01

    Iontophoresis is an effective and safe treatment for hyperhidrosis. We investigated patients\\' experiences with the Idrostar® home iontophoresis unit (STD Pharmaceuticals, Hereford, UK) considering compliance and efficacy.

  17. [Support Team for Investigator-Initiated Clinical Research].

    Science.gov (United States)

    Fujii, Hisako

    2017-07-01

    Investigator-initiated clinical research is that in which investigators plan and carry out their own clinical research in academia. For large-scale clinical research, a team should be organized and implemented. This team should include investigators and supporting staff, who will promote smooth research performance by fulfilling their respective roles. The supporting staff should include project managers, administrative personnel, billing personnel, data managers, and clinical research coordinators. In this article, I will present the current status of clinical research support and introduce the research organization of the Dominantly Inherited Alzheimer Network (DIAN) study, an investigator-initiated international clinical research study, with particular emphasis on the role of the project management staff and clinical research coordinators.

  18. Evaluation of a Bioabsorbable Self-Expandable Vein Stent-Base Made of Poly(l-lactide) In Vitro and In Vivo

    Energy Technology Data Exchange (ETDEWEB)

    Løvdal, Alexandra Liv Vest, E-mail: alvlo@nanotech.dtu.dk [Technical University of Denmark, Department of Micro- and Nanotechnology (Denmark); Calve, Sarah [Purdue University, Weldon School of Biomedical Engineering (United States); Yang, Shuo; Alstine, William Van [Cook Research Incorporated (United States); Binkert, Christoph A. [Institut für Radiologie, Kantonsspital Winterthur (Switzerland); Klausen, Kasper [William Cook Europe (Denmark)

    2017-01-15

    PurposeThis study was designed to evaluate performance and tissue response to a self-expandable bioabsorbable vein stent-base cut from a tube with enhanced stiffness and strength in vitro and in vivo.MethodsA diamond-shaped stent-base was cut from a sequential biaxially strained poly(l-lactide) (PLLA) tube for optimized performance. The performance of the stent-base was evaluated in a finite element analysis model, and validation was attempted in vitro through a cyclic flat-plate compression and radial force measurement. The performance of the stent-base was tested in vivo using 3 sheep with 2 implants each for 2 and 3½ weeks, respectively.ResultsIn vitro the stent-base showed an elliptical deformation but no fractures. In vivo the stent-base showed adequate radial force and no migration. All implanted stent-bases showed multiple fractures not only at the predicted stress zones but at all connecting points. Fragments of the caudal stent-base stayed in the vein wall indicating sufficient tissue coverage to avoid embolization of the fractured stent pieces, whereas fragments from the cranial device remaining were few. Neointima formation was confirmed histologically at 2 and 3½ weeks.ConclusionA bioabsorbable self-expandable stent-base made from PLLA for large veins seems feasible, but over time, the PLLA used in this study appears too stiff and lacks the sufficient flexibility to move with the vena cava, causing multiple fractures.

  19. Role of Self-help Groups in Promoting Inclusion and Rights of Persons with Disabilities

    Directory of Open Access Journals (Sweden)

    K P Kumaran

    2011-10-01

    Full Text Available Purpose:This study examined the role of self help groups in addressing some of the problems faced by persons with disabilities such as social exclusion, discrimination, lack of awareness about their rights and privileges, and absence of livelihood programmes.Method: One hundred persons with disabilities were randomly drawn for the study from 50 self help groups in 2 districts that were covered under a popular poverty alleviation programme implemented by the state of Andhra Pradesh  in India.  An interview schedule was used to collect information.Results: Before joining the group, some of the persons with disabilities were mostly confined to their houses, and viewed as less productive and incapable of leading a ‘normal’ life. After joining the groups, they came out of their seclusion and started to work together for their collective welfare and development. They gained knowledge about their rights and privileges and started income generation activities with the help of loans made available to them.  They gained better acceptance within their families, but attitudes of their communities was slower to change. A feeling that “disability is not inability” seemed to have been internalized among the members of the groups.Conclusion: Self-help groups can be very effective in helping persons with disabilities to come out of their isolation and in promoting their participation and inclusion in societal mainstream.Key Words: Self-help group, persons with disabilitiesdoi 10.5463/DCID.v22i2.78

  20. Evaluation of a Bioabsorbable Self-Expandable Vein Stent-Base Made of Poly(l-lactide) In Vitro and In Vivo

    International Nuclear Information System (INIS)

    Løvdal, Alexandra Liv Vest; Calve, Sarah; Yang, Shuo; Alstine, William Van; Binkert, Christoph A.; Klausen, Kasper

    2017-01-01

    PurposeThis study was designed to evaluate performance and tissue response to a self-expandable bioabsorbable vein stent-base cut from a tube with enhanced stiffness and strength in vitro and in vivo.MethodsA diamond-shaped stent-base was cut from a sequential biaxially strained poly(l-lactide) (PLLA) tube for optimized performance. The performance of the stent-base was evaluated in a finite element analysis model, and validation was attempted in vitro through a cyclic flat-plate compression and radial force measurement. The performance of the stent-base was tested in vivo using 3 sheep with 2 implants each for 2 and 3½ weeks, respectively.ResultsIn vitro the stent-base showed an elliptical deformation but no fractures. In vivo the stent-base showed adequate radial force and no migration. All implanted stent-bases showed multiple fractures not only at the predicted stress zones but at all connecting points. Fragments of the caudal stent-base stayed in the vein wall indicating sufficient tissue coverage to avoid embolization of the fractured stent pieces, whereas fragments from the cranial device remaining were few. Neointima formation was confirmed histologically at 2 and 3½ weeks.ConclusionA bioabsorbable self-expandable stent-base made from PLLA for large veins seems feasible, but over time, the PLLA used in this study appears too stiff and lacks the sufficient flexibility to move with the vena cava, causing multiple fractures.

  1. Investigating the Jack the Ripper Case: Engaging Students in a Criminal Investigations Class through Active Learning

    Science.gov (United States)

    Gutierrez, Daniel; Kazmi, Syed

    2010-01-01

    The present study examines the utilization of a class project involving the Jack the Ripper murders. Students enrolled in a criminal investigations class were required to investigate the five canonical murders associated with the infamous serial killer known as Jack the Ripper and the murders that occurred in London during 1888. This paper…

  2. Numerical Study of Condensation Heat Exchanger Design in a Cooling jacket: Correlation Investigation

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Myoung Jun; Lee, Hee Joon [Kookmin Univ., Seoul (Korea, Republic of); Kang, Han Ok; Lee, Tae Ho; Park, Cheon Tae [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2013-10-15

    In this study, condensing heat transfer correlation of TSCON is evaluated with the existing experimental data set to design condensation heat exchanger without noncondensable gas effect (pure steam condensation) in a cooling jacket. From the investigation of the existing condensation heat transfer correlation to the existing experimental data, the improved Shah's correlation showed most satisfactory result for the condensation heat transfer coefficient with experimental data of Khun in a cooling jacket, whereas the Shah's correlation with experimental data of Lee. Lee et al. reported the improved Shah correlation gave us the best predictor for the condensation heat transfer data of Kim and Henderson in a subcooled and saturated water pool. They suggested the improved Shah correlation should be adopted as condensation heat transfer module in TSCON(Thermal Sizing of CONdenser) to design condensation heat exchanger in secondary passive cooling system of nuclear plant.

  3. Study protocol: a randomized controlled trial investigating the effects of a psychosexual training program for adolescents with autism spectrum disorder.

    Science.gov (United States)

    Visser, Kirsten; Greaves-Lord, Kirstin; Tick, Nouchka T; Verhulst, Frank C; Maras, Athanasios; van der Vegt, Esther J M

    2015-08-28

    Previous research shows that adolescents with autism spectrum disorder (ASD) run several risks in their psychosexual development and that these adolescents can have limited access to reliable information on puberty and sexuality, emphasizing the need for specific guidance of adolescents with ASD in their psychosexual development. Few studies have investigated the effects of psychosexual training programs for adolescents with ASD and to date no randomized controlled trials are available to study the effects of psychosexual interventions for this target group. The randomized controlled trial (RCT) described in this study protocol aims to investigate the effects of the Tackling Teenage Training (TTT) program on the psychosexual development of adolescents with ASD. This parallel clinical trial, conducted in the South-West of the Netherlands, has a simple equal randomization design with an intervention and a waiting-list control condition. Two hundred adolescents and their parents participate in this study. We assess the participants in both conditions using self-report as well as parent-report questionnaires at three time points during 1 year: at baseline (T1), post-treatment (T2), and for follow-up (T3). To our knowledge, the current study is the first that uses a randomized controlled design to study the effects of a psychosexual training program for adolescents with ASD. It has a number of methodological strengths, namely a large sample size, a wide range of functionally relevant outcome measures, the use of multiple informants, and a standardized research and intervention protocol. Also some limitations of the described study are identified, for instance not making a comparison between two treatment conditions, and no use of blinded observational measures to investigate the ecological validity of the research results. Dutch Trial Register NTR2860. Registered on 20 April 2011.

  4. Investigation and study on each technique and example of intelligent planning; Intelligent planning no kakushu shuho to jirei ni kansuru chosa kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-11

    Various problems on intelligent planning (IP) and the tendency of basic technology were investigated. For each technique of IP, a Petri net and mark graph have been widely used as the modeling and analysis methods of a discrete event system. Moreover, various planning problems were modeled by a traveling salesman problem, and the efficient solution of the traveling salesman problem has been studied simultaneously. The tendency of the basic technology and application system viewed from an example of intelligent plant planning was investigated as an applied field of planning technology, with importance attached to the production system and robot planning. In the scheduling technology of the production system, the activation of an AI study and a new theory (i.e., architecture study) based on natural science information was investigated with the transition in the world as a trigger. A robot system has been planned in a wide range such as the environmental information acquisition planning of a robot. 202 refs., 69 figs., 4 tabs.

  5. Camera trap arrays improve detection probability of wildlife: Investigating study design considerations using an empirical dataset.

    Science.gov (United States)

    O'Connor, Kelly M; Nathan, Lucas R; Liberati, Marjorie R; Tingley, Morgan W; Vokoun, Jason C; Rittenhouse, Tracy A G

    2017-01-01

    Camera trapping is a standard tool in ecological research and wildlife conservation. Study designs, particularly for small-bodied or cryptic wildlife species often attempt to boost low detection probabilities by using non-random camera placement or baited cameras, which may bias data, or incorrectly estimate detection and occupancy. We investigated the ability of non-baited, multi-camera arrays to increase detection probabilities of wildlife. Study design components were evaluated for their influence on wildlife detectability by iteratively parsing an empirical dataset (1) by different sizes of camera arrays deployed (1-10 cameras), and (2) by total season length (1-365 days). Four species from our dataset that represented a range of body sizes and differing degrees of presumed detectability based on life history traits were investigated: white-tailed deer (Odocoileus virginianus), bobcat (Lynx rufus), raccoon (Procyon lotor), and Virginia opossum (Didelphis virginiana). For all species, increasing from a single camera to a multi-camera array significantly improved detection probability across the range of season lengths and number of study sites evaluated. The use of a two camera array increased survey detection an average of 80% (range 40-128%) from the detection probability of a single camera across the four species. Species that were detected infrequently benefited most from a multiple-camera array, where the addition of up to eight cameras produced significant increases in detectability. However, for species detected at high frequencies, single cameras produced a season-long (i.e, the length of time over which cameras are deployed and actively monitored) detectability greater than 0.75. These results highlight the need for researchers to be critical about camera trap study designs based on their intended target species, as detectability for each focal species responded differently to array size and season length. We suggest that researchers a priori identify

  6. Camera trap arrays improve detection probability of wildlife: Investigating study design considerations using an empirical dataset.

    Directory of Open Access Journals (Sweden)

    Kelly M O'Connor

    Full Text Available Camera trapping is a standard tool in ecological research and wildlife conservation. Study designs, particularly for small-bodied or cryptic wildlife species often attempt to boost low detection probabilities by using non-random camera placement or baited cameras, which may bias data, or incorrectly estimate detection and occupancy. We investigated the ability of non-baited, multi-camera arrays to increase detection probabilities of wildlife. Study design components were evaluated for their influence on wildlife detectability by iteratively parsing an empirical dataset (1 by different sizes of camera arrays deployed (1-10 cameras, and (2 by total season length (1-365 days. Four species from our dataset that represented a range of body sizes and differing degrees of presumed detectability based on life history traits were investigated: white-tailed deer (Odocoileus virginianus, bobcat (Lynx rufus, raccoon (Procyon lotor, and Virginia opossum (Didelphis virginiana. For all species, increasing from a single camera to a multi-camera array significantly improved detection probability across the range of season lengths and number of study sites evaluated. The use of a two camera array increased survey detection an average of 80% (range 40-128% from the detection probability of a single camera across the four species. Species that were detected infrequently benefited most from a multiple-camera array, where the addition of up to eight cameras produced significant increases in detectability. However, for species detected at high frequencies, single cameras produced a season-long (i.e, the length of time over which cameras are deployed and actively monitored detectability greater than 0.75. These results highlight the need for researchers to be critical about camera trap study designs based on their intended target species, as detectability for each focal species responded differently to array size and season length. We suggest that researchers a priori

  7. Initial Experience with Balloon-Occluded Trans-catheter Arterial Chemoembolization (B-TACE) for Hepatocellular Carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Maruyama, Mitsunari, E-mail: mitunari@med-shimane.u.ac.jp; Yoshizako, Takeshi, E-mail: yosizako@med.shimane-u.ac.jp; Nakamura, Tomonori, E-mail: t-naka@med.shimane-u.ac.jp; Nakamura, Megumi, E-mail: megumi@med.shimane-u.ac.jp; Yoshida, Rika, E-mail: yoshidar@med.shimane-u.ac.jp; Kitagaki, Hajime, E-mail: kitagaki@med.shimane-u.ac.jp [Shimane University Faculty of Medicine, Department of Radiology (Japan)

    2016-03-15

    PurposeThis study was performed to evaluate the accumulation of lipiodol emulsion (LE) and adverse events during our initial experience of balloon-occluded trans-catheter arterial chemoembolization (B-TACE) for hepatocellular carcinoma (HCC) compared with conventional TACE (C-TACE).MethodsB-TACE group (50 cases) was compared with C-TACE group (50 cases). The ratio of the LE concentration in the tumor to that in the surrounding embolized liver parenchyma (LE ratio) was calculated after each treatment. Adverse events were evaluated according to the Common Terminology Criteria for Adverse Effects (CTCAE) version 4.0.ResultsThe LE ratio at the level of subsegmental showed a statistically significant difference between the groups (t test: P < 0.05). Only elevation of alanine aminotransferase was more frequent in the B-TACE group, showing a statistically significant difference (Mann–Whitney test: P < 0.05). While B-TACE caused severe adverse events (liver abscess and infarction) in patients with bile duct dilatation, there was no statistically significant difference in incidence between the groups. Multivariate logistic regression analysis suggested that the significant risk factor for liver abscess/infarction was bile duct dilatation (P < 0.05).ConclusionThe LE ratio at the level of subsegmental showed a statistically significant difference between the groups (t test: P < 0.05). B-TACE caused severe adverse events (liver abscess and infarction) in patients with bile duct dilatation.

  8. Students leaving the STEM pipeline : an investigation of their attitudes and the influence of significant others on their study choice

    NARCIS (Netherlands)

    Korpershoek, Hanke; Kuyper, Hans; Bosker, Roel; van der Werf, Margaretha

    2013-01-01

    The main aim of the present study was to investigate why some students do not continue in science-oriented studies in higher education despite that their previous career in secondary education proved that they were interested and suitably qualified to do so. We introduced a new approach to deal with

  9. Ecological risk assessment guidance for preparation of remedial investigation/feasibility study work plans

    International Nuclear Information System (INIS)

    Pentecost, E.D.; Vinikour, W.S.

    1993-08-01

    This guidance document (1) provides instructions on preparing the components of an ecological work plan to complement the overall site remedial assessment investigation/feasibility study (RI/FS) work plan and (2) directs the user on how to implement ecological tasks identified in the plan. Under the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA), as amended by the Superfired Amendments and Reauthorization Act of 1986 (SARA), an RI/FS work plan win have to be developed as part of the site-remediation scoping the process. Specific guidance on the RI/FS process and the preparation of work plans has been developed by the US Environmental Protection Agency (EPA 1988a). This document provides guidance to US Department of Energy (DOE) staff and contractor personnel for incorporation of ecological information into environmental remediation planning and decision making at CERCLA sites. An overview analysis of early ecological risk assessment methods (i.e., in the 1980s) at Superfund sites was conducted by the EPA (1989a). That review provided a perspective of attention given to ecological issues in some of the first RI/FS studies. By itself, that reference is of somewhat limited value; it does, however, establish a basis for comparison of past practices in ecological risk with current, more refined methods

  10. Site investigations for the disposal of spent fuel - investigation program

    International Nuclear Information System (INIS)

    Aeikaes, Timo

    1985-11-01

    The Industrial Power Company Ltd (TVO) is making preparations for the final disposal of spent nuclear fuel into the Finnish bedrock. The revised site investigation program for the years 1986-2010 is presented in this report. The objectives and activities in the near future are described in more detail. The main objectives and frame programs for the investigations in the more distant future are described. The program planning of these investigations are being developed in the preceding site investigations. The investigations for the site selection are divided into four phases: 1983-1985 selection of the investigation areas, preparations for the field investigations, drilling and investigations in a deep test borehole; 1986-1992 preliminary site investigations in 5-10 investigation areas; 1993-2000 detailed site investigations in 2-3 investigation areas. Site selection in the year 2000; 2001-2010 complementary investigations on the selected site. The first investigation phase will be carried out as planned. In this phase a 1001 m deep test borehole was drilled at Lavia in western Finland. With the investigations in the borehole and related development work, preparations were made for the future field investigations. The equipment and investigation methods are being developed during the site investigations. The equipment for taking groundwater samples and the unit for hydraulic testing have been developed. In the future the emphasis in the work will be in developing equipment for monitoring of the hydraulic head and measuring the volumetric flow. In groundwater sampling the present procedure can be improved by adding the test for the in-situ measurements. The results of the field investigations will be stored and processed in a centralized data base. The data base will transmit the results for the interpretation and then the interpreted results transmitted for model calculations and reporting. The cost estimate for the investigations in 1986-2010 is 110-125 million

  11. An Investigation into How Female Teachers Manage Stress and Teacher Burnout: A Case Study of West Akim Municipality of Ghana

    Science.gov (United States)

    Addison, Asonaba Kofi; Yankyera, George

    2015-01-01

    The purpose of this study was to investigate into how female teachers in Asamankese Circuit II in West Akim Municipality of Ghana Education Service manage stress and teacher burnout, and explore the causes, effects, and ways of improving work-related stress for better standard of education. The study was conducted with qualitative research…

  12. The Pinellas Plant RCRA facility investigation - A case study

    International Nuclear Information System (INIS)

    Kilbury, Richard; Keshian, Berg; Farley, Dwain; Meyer, David; Ingle, David; Biedermann, Charles

    1992-01-01

    Under the direction of the U.S. Department of Energy Albuquerque Field Office Environmental Restoration Program, a Resource Conservation and Recovery Act (RCRA) Facility Investigation (RFI) was completed at the Pinellas Plant to fulfill requirements of the Hazardous and Solid Waste Amendments of 1984 (HSWA) permit issued on February 9, 1990 by the U.S. Environmental Protection Agency (EPA). This RFI addressed potential contaminant releases and environmental conditions at 15 solid waste management units (SWMUs). The RFI characterization program began in April 1990 and was completed in May 1991. The scope of RFI data collection activities is presented in the Pinellas Plant RFI Workplan issued in May 1990 and approved by EPA on April 16, 1991. An RFI Report was submitted to EPA on September 1, 1991. This paper presents a summary of RFI results and conclusions. Primary environmental concerns at the Pinellas Plant are emphasized. (author)

  13. Investigating the relationship between predictability and imbalance in minimisation: a simulation study

    Science.gov (United States)

    2013-01-01

    Background The use of restricted randomisation methods such as minimisation is increasing. This paper investigates under what conditions it is preferable to use restricted randomisation in order to achieve balance between treatment groups at baseline with regard to important prognostic factors and whether trialists should be concerned that minimisation may be considered deterministic. Methods Using minimisation as the randomisation algorithm, treatment allocation was simulated for hypothetical patients entering a theoretical study having values for prognostic factors randomly assigned with a stipulated probability. The number of times the allocation could have been determined with certainty and the imbalances which might occur following randomisation using minimisation were examined. Results Overall treatment balance is relatively unaffected by reducing the probability of allocation to optimal treatment group (P) but within-variable balance can be affected by any P <1. This effect is magnified by increased numbers of prognostic variables, the number of categories within them and the prevalence of these categories within the study population. Conclusions In general, for smaller trials, probability of treatment allocation to the treatment group with fewer numbers requires a larger value P to keep treatment and variable groups balanced. For larger trials probability of allocation values from P = 0.5 to P = 0.8 can be used while still maintaining balance. For one prognostic variable there is no significant benefit in terms of predictability in reducing the value of P. However, for more than one prognostic variable, significant reduction in levels of predictability can be achieved with the appropriate choice of P for the given trial design. PMID:23537389

  14. Scoping study investigating stakeholder perceptions and use of school canteens in an Australian city.

    Science.gov (United States)

    Lawlis, Tanya; Eckley, Dionne; Jamieson, Maggie; Knox, Melissa

    2017-11-01

    To investigate stakeholder perceptions of healthy food availability in school canteens, the promotion of healthy foods and canteen policy compliance. This is a cross-sectional study of Catholic and independent primary and high schools comprising three investigative phases: (i) survey of 39 schools, (ii) survey of canteen managers and parents from 10 schools and (iii) an audit of school menus against National Healthy School Canteen Guidelines. Total participants included: 6 principals, no canteen mangers and 86 parents from two schools; 24 menus were audited. Schools are committed to supporting healthy eating, with participants agreeing canteens should follow the National Health School Canteen Guidelines. A total of 94% of parents (n = 81/86) indicated that their children buy food from the school canteen, with commonly purchased items mostly classified as 'red'. Despite this food choice, parents (n = 32/48) indicated they had a responsibility to encourage healthy eating. No school canteen menu comprised +50% 'green' foods and thus did not comply with the National Healthy School Canteen Guidelines. Despite the intense focus on school canteens to sell healthy food, little has changed in terms of student's food choices and the barriers to providing healthy options. The external environment and divided parental buy-in impact the canteen's ability to comply with guidelines. A holistic approach involving all stakeholder levels is required to successfully achieve a healthy school canteen environment and positively influence student's food habits and choices. © 2017 Dietitians Association of Australia.

  15. A mechanistic investigation on the formation and rearrangement of silaspiropentane: A theoretical study.

    Science.gov (United States)

    Yildiz, Cem Burak; Azizoglu, Akin

    2016-07-01

    The formation of silaspiropentane from addition of singlet silacyclopropylidene 1 and silacyclopropylidenoid 8 to ethylene has been investigated separately at the B3LYP, X3LYP, WB97XD, and M05-2X theories using the 6-31+G(d,p) basis set. The silacycloproylidenoid addition follows a stepwise route. In contrast, a concerted mechanism occurs for silacyclopropylidene addition. Moreover, the intramolecular rearrangements of silaspiropentane 9 to methylenesilacyclobutane 11 and 2-silaallene + ethylene 12 have been studied extensively. The required energy barrier for the isomerization of 9 to 10 was determined to be 44.0 kcal mol(-1) at the B3LYP/6-31+G(d,p) level. After formation of 10, the rearrangement to methylenesilacyclobutane 12 is highly exergonic by -15.9 kcal mol(-1), which makes this reaction promising. However, the conversion of 9 to 11 is calculated to be quite endergonic, by 26.5 kcal mol(-1).

  16. The electro-optical and charge transport study of imidazolidin derivative: Quantum chemical investigations

    Directory of Open Access Journals (Sweden)

    Ahmad Irfan

    2016-11-01

    Full Text Available Imidazolidin derivatives gained significant attention in our daily life from better biological activity to the semiconducting materials. The present investigation deals with the in depth study of (Z-2-sulfanylidene-5-(thiophen-2-ylmethylideneimidazolidin-4-one (STMI with respect to their structural, electronic, optical and charge transport properties as semiconducting material. The ground and first excited state geometries were optimized by applying density functional theory (DFT and time dependent DFT, respectively. The light has been shed on the frontier molecular orbitals (FMOs and observed comprehensible intramolecular charge transfer (ICT from the highest occupied molecular orbitals (HOMOs to the lowest unoccupied molecular orbitals (LUMOs. The absorption, emission, ionization potentials (IP, electron affinities (EA, total and partial densities of states and structure-property relationship have been discussed. Finally, hole as well as electron reorganization energies, transfer integrals and intrinsic mobilities have been calculated then charge transport behavior of STMI was discussed, intensively.

  17. Charge breeding investigation in EBIS/T and collision study of ions with cold atoms for HITRAP

    Energy Technology Data Exchange (ETDEWEB)

    Sokolov, Alexey

    2010-01-29

    Highly charged ions (HCI) at low velocities or at rest are interesting systems for various atomic physics experiments. For investigations on HCI of heavy stable or radioactive nuclides the HITRAP (Highly charged Ion TRAP) decelerator facility has been set up at GSI to deliver cooled beams of HCI at an energy of 5 keV/q. The HCI are produced in a stripper foil at relativistic energies and are decelerated in several steps at ESR storage ring and HITRAP before they are delivered to experimental setups. One of the experiments is the investigation of multi-electron charge exchange in collisions of heavy HCI with cold atoms using novel MOTRIMS technique. Collision experiments on light ions from an ECR ion source colliding with cold atoms in a MOT have been performed and the results are described. An electron beam ion trap (EBIT) has been tested and optimized for commissioning of the HITRAP physics experiments. The process of charge breeding in the EBIT has been successfully studied with gaseous elements and with an alkaline element injected from an external ion source. (orig.)

  18. Charge breeding investigation in EBIS/T and collision study of ions with cold atoms for HITRAP

    International Nuclear Information System (INIS)

    Sokolov, Alexey

    2010-01-01

    Highly charged ions (HCI) at low velocities or at rest are interesting systems for various atomic physics experiments. For investigations on HCI of heavy stable or radioactive nuclides the HITRAP (Highly charged Ion TRAP) decelerator facility has been set up at GSI to deliver cooled beams of HCI at an energy of 5 keV/q. The HCI are produced in a stripper foil at relativistic energies and are decelerated in several steps at ESR storage ring and HITRAP before they are delivered to experimental setups. One of the experiments is the investigation of multi-electron charge exchange in collisions of heavy HCI with cold atoms using novel MOTRIMS technique. Collision experiments on light ions from an ECR ion source colliding with cold atoms in a MOT have been performed and the results are described. An electron beam ion trap (EBIT) has been tested and optimized for commissioning of the HITRAP physics experiments. The process of charge breeding in the EBIT has been successfully studied with gaseous elements and with an alkaline element injected from an external ion source. (orig.)

  19. Policy Forum: Studying Eyewitness Investigations in the Field

    Science.gov (United States)

    Dawes, Robyn; Jacoby, Larry L.; Kahneman, Daniel; Lempert, Richard; Roediger, Henry L.; Rosenthal, Robert

    2007-01-01

    This article considers methodological issues arising from recent efforts to provide field tests of eyewitness identification procedures. We focus in particular on a field study (Mecklenburg 2006) that examined the “double blind, sequential” technique, and consider the implications of an acknowledged methodological confound in the study. We explain why the confound has severe consequences for assessing the real-world implications of this study. PMID:17610149

  20. Investigating Variations in Gameplay: Cognitive Implications

    Directory of Open Access Journals (Sweden)

    Kamran Sedig

    2015-01-01

    Full Text Available There is increasing interest in creating computer games for learning, problem solving, and other high-level cognitive activities. When investigating whether gameplay is conducive to such activities, gameplay is often studied as a whole. As a result, cognitive implications can be linked to the game but not to its structural elements. Given that gameplay arises from interaction between the player and the game, it is the structural components of interaction that should be investigated to better understand the design of gameplay. Furthermore, minor variations in the components of interaction can have significant cognitive implications. However, such variation has not been studied yet. Thus, to gain a better understanding of how we can study the effect of interaction on the cognitive aspect of gameplay, we conducted an exploratory investigation of two computer games. These games were isomorphic at a deep level and only had one minor difference in the structure of their interaction. Volunteers played these games and discussed the cognitive processes that emerged. In one game, they primarily engaged in planning, but in the other game they primarily engaged in visualizing. This paper discusses the results of our investigation as well as its implications for the design of computer games.

  1. Investigation of polyurea-crosslinked silica aerogels as a neuronal scaffold: a pilot study.

    Directory of Open Access Journals (Sweden)

    Firouzeh Sabri

    Full Text Available BACKGROUND: Polymer crosslinked aerogels are an attractive class of materials for future implant applications particularly as a biomaterial for the support of nerve growth. The low density and nano-porous structure of this material combined with large surface area, high mechanical strength, and tunable surface properties, make aerogels materials with a high potential in aiding repair of injuries of the peripheral nervous system. however, the interaction of neurons with aerogels remains to be investigated. METHODOLOGY: In this work the attachment and growth of neurons on clear polyurea crosslinked silica aerogels (PCSA coated with: poly-L-lysine, basement membrane extract (BME, and laminin1 was investigated by means of optical and scanning electron microscopy. After comparing the attachment and growth capability of neurons on these different coatings, laminin1 and BME were chosen for nerve cell attachment and growth on PCSA surfaces. The behavior of neurons on treated petri dish surfaces was used as the control and behavior of neurons on treated PCSA discs was compared against it. CONCLUSIONS/SIGNIFICANCE: This study demonstrates that: 1 untreated PCSA surfaces do not support attachment and growth of nerve cells, 2 a thin application of laminin1 layer onto the PCSA discs adhered well to the PCSA surface while also supporting growth and differentiation of neurons as evidenced by the number of processes extended and b3-tubulin expression, 3 three dimensional porous structure of PCSA remains intact after fixing protocols necessary for preservation of biological samples and 4 laminin1 coating proved to be the most effective method for attaching neurons to the desired regions on PCSA discs. This work provides the basis for potential use of PCSA as a biomaterial scaffold for neural regeneration.

  2. An Investigation of Factors Motivating Student’s Study at The International Hotel Management Institute Switzerland

    Directory of Open Access Journals (Sweden)

    Hengky Efendy

    2010-05-01

    Full Text Available Nowadays, in this era of globalisation the hospitality industry needs well educated employees. Therefore the hotel school has to provide human resources to fit any position in the hospitality industry. The author chose the International Hotel Management Institute (IMI-Switzerland for research too specifically investigates factors affecting students’ motivations to study. The author’s experience was that many students of hospitality are not very motivated to study hotel management. Students get bored while having lectures, are not motivated to go to the library to research, and yet to be educated is the main reasons that students come to IMI to study hospitality. The author has set several objectives in chapter two to ensure the flow of this research. The literature review will be covered in motivating of students study for hotel school education.Literature review which is critically analysed by the author was chosen by the author according the field of study. The sample chosen for this research was motivation students study from first, second, third and fourth year students in IMI- Switzerland Several motivation of this research was the reference book of this field study, and the length of time for making this dissertation. After the primary data were collected and analysed, it was discovered that most of all students in IMI-Switzerland is to have a better chance of getting a job after finishing the course. 

  3. Investigating the Interaction of Fe Nanoparticles with Lysozyme by Biophysical and Molecular Docking Studies.

    Directory of Open Access Journals (Sweden)

    Zahra Aghili

    Full Text Available Herein, the interaction of hen egg white lysozyme (HEWL with iron nanoparticle (Fe NP was investigated by spectroscopic and docking studies. The zeta potential analysis revealed that addition of Fe NP (6.45±1.03 mV to HEWL (8.57±0.54 mV can cause to greater charge distribution of nanoparticle-protein system (17.33±1.84 mV. In addition, dynamic light scattering (DLS study revealed that addition of Fe NP (92.95±6.11 nm to HEWL (2.68±0.37 nm increases suspension potential of protein/nanoparticle system (51.17±3.19 nm. Fluorescence quenching studies reveled that both static and dynamic quenching mechanism occur and hydrogen bond and van der Waals interaction give rise to protein-NP system. Synchronous fluorescence spectroscopy of HEWL in the presence of Fe NP showed that the emission maximum wavelength of tryptophan (Trp residues undergoes a red-shift. ANS fluorescence data indicated a dramatic exposure of hydrophobic residues to the solvent. The considerable reduction in melting temperature (T(m of HEWL after addition of Fe NP determines an unfavorable interaction system. Furthermore circular dichoroism (CD experiments demonstrated that, the secondary structure of HEWL has not changed with increasing Fe NP concentrations; however, some conformational changes occur in tertiary structure of HEWL. Moreover, protein-ligand docking study confirmed that the Fe NP forms hydrogen bond contacts with HEWL.

  4. Lab-scale impact test to investigate the pipe-soil interaction and comparative study to evaluate structural responses

    Directory of Open Access Journals (Sweden)

    Dong-Man Ryu

    2015-07-01

    Full Text Available This study examined the dynamic response of a subsea pipeline under an impact load to determine the effect of the seabed soil. A laboratory-scale soil-based pipeline impact test was carried out to investigate the pipeline deformation/strain as well as the interaction with the soil-pipeline. In addition, an impact test was simulated using the finite element technique, and the calculated strain was compared with the experimental results. During the simulation, the pipeline was described based on an elasto-plastic analysis, and the soil was modeled using the Mohr-Coulomb fail-ure criterion. The results obtained were compared with ASME D31.8, and the differences between the analysis results and the rules were specifically investigated. Modified ASME formulae were proposed to calculate the precise structural behavior of a subsea pipeline under an impact load when considering sand- and clay-based seabed soils.

  5. Synthesis, structure, spectroscopic investigations, and computational studies of optically pure β-ketoamide

    International Nuclear Information System (INIS)

    Mtat, D.; Touati, R.; Guerfel, T.; Walha, K.; Ben Hassine, B.

    2016-01-01

    Chemical preparation, X-ray single crystal diffraction, IR and NMR spectroscopic investigations of a novel nonlinear optical organic compound (C 17 H 22 NO 2 Cl) are described. The compound crystallizes in the orthorhombic system with the non-centrosymmetric sp. gr. P2 1 2 1 2 1 . In the crystal structure, molecules are interconnected by N–H…O hydrogen bonds forming infinite chains along a axis. The Hirshfeld surface and associated fingerprint plots of the compound are presented to explore the nature of intermolecular interactions and their relative contributions in building the solid-state architecture. The molecular HOMO–LUMO compositions and their respective energy gaps are also drawn to explain the activity of the compound. The first hyperpolarizability β tot of the title compound is determined using DFT calculations. The optical properties are also investigated by UV–Vis absorption spectrum.

  6. Main nutrient patterns and colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition study.

    Science.gov (United States)

    Moskal, Aurélie; Freisling, Heinz; Byrnes, Graham; Assi, Nada; Fahey, Michael T; Jenab, Mazda; Ferrari, Pietro; Tjønneland, Anne; Petersen, Kristina En; Dahm, Christina C; Hansen, Camilla Plambeck; Affret, Aurélie; Boutron-Ruault, Marie-Christine; Cadeau, Claire; Kühn, Tilman; Katzke, Verena; Iqbal, Khalid; Boeing, Heiner; Trichopoulou, Antonia; Bamia, Christina; Naska, Androniki; Masala, Giovanna; de Magistris, Maria Santucci; Sieri, Sabina; Tumino, Rosario; Sacerdote, Carlotta; Peeters, Petra H; Bueno-de-Mesquita, Bas H; Engeset, Dagrun; Licaj, Idlir; Skeie, Guri; Ardanaz, Eva; Buckland, Genevieve; Castaño, José M Huerta; Quirós, José R; Amiano, Pilar; Molina-Portillo, Elena; Winkvist, Anna; Myte, Robin; Ericson, Ulrika; Sonestedt, Emily; Perez-Cornago, Aurora; Wareham, Nick; Khaw, Kay-Tee; Huybrechts, Inge; Tsilidis, Konstantinos K; Ward, Heather; Gunter, Marc J; Slimani, Nadia

    2016-11-22

    Much of the current literature on diet-colorectal cancer (CRC) associations focused on studies of single foods/nutrients, whereas less is known about nutrient patterns. We investigated the association between major nutrient patterns and CRC risk in participants of the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Among 477 312 participants, intakes of 23 nutrients were estimated from validated dietary questionnaires. Using results from a previous principal component (PC) analysis, four major nutrient patterns were identified. Hazard ratios (HRs) and 95% confidence intervals (CIs) were computed for the association of each of the four patterns and CRC incidence using multivariate Cox proportional hazards models with adjustment for established CRC risk factors. During an average of 11 years of follow-up, 4517 incident cases of CRC were documented. A nutrient pattern characterised by high intakes of vitamins and minerals was inversely associated with CRC (HR per 1 s.d.=0.94, 95% CI: 0.92-0.98) as was a pattern characterised by total protein, riboflavin, phosphorus and calcium (HR (1 s.d.)=0.96, 95% CI: 0.93-0.99). The remaining two patterns were not significantly associated with CRC risk. Analysing nutrient patterns may improve our understanding of how groups of nutrients relate to CRC.

  7. AN EXPLORATORY STUDY INVESTIGATING THE EFFECTS OF A TREATMENT MANUAL FOR VIDEO GAME ADDICTION.

    Science.gov (United States)

    Pallesen, Ståle; Lorvik, Ingjerd Meen; Bu, Eli Hellandsjø; Molde, Helge

    2015-10-01

    This study investigated the effects of a manualized therapy for video game addiction in 12 males, ages 14-18 yr. The manual was based on cognitive-behavioral therapy, short-term strategic family therapy, solution-focused therapy, and motivational interviewing. Treatment response was reported by the patients, their mothers, and the therapists. The patients reported moderate (but statistically non-significant) improvement from pre- to post-treatment. The mothers, however, reported large effects and statistically significant improvement from pre- to post-treatment. The therapists reported marked or moderate treatment response in six of the 12 patients. The ratings of change by mothers converged well with the views of change of both the patients and therapists, whereas the convergence of views on change between the two latter sources was far lower.

  8. Primary chronic osteomyelitis of the jaw--a microbial investigation using cultivation and DNA analysis: a pilot study.

    Science.gov (United States)

    Frid, Paula; Tornes, Knut; Nielsen, Øyunn; Skaug, Nils

    2009-05-01

    The aims of this study were to investigate the infectious etiology of primary chronic osteomyelitis (PCO) of the jaw using an extraoral sampling approach and molecular methods. In this pilot study, bone biopsies from the mandibles of 5 patients with PCO were sampled with an extraoral sterile approach. Cultivation and polymerase chain reaction (PCR) were performed. Two of the biopsies yielded growth of Propionebacterium acnes. One biopsy also demonstrated Staphylococcus capitis. The biopsies with bacterial growth were also positive for the same bacteria by PCR analysis. No specific bacterial etiology was demonstrated. However, the results of bacterial cultivation and PCR analysis were in agreement. Based on these findings, the molecular procedure used in this study can be considered to be suitable for identification of bacterial specimens in mandibular biopsies. Further studies are needed with larger patient populations to confirm these findings.

  9. Investigation/evaluation of water cooled fast reactor in the feasibility study on commercialized fast reactor cycle systems. Intermediate evaluation of phase-II study

    International Nuclear Information System (INIS)

    Kotake, Syoji; Nishikawa, Akira

    2005-01-01

    Feasibility study on commercialized fast reactor cycle systems aims at investigation and evaluation of FBR design requirement's attainability, operation and maintenance, and technical feasibility of the candidate system. Development targets are 1) ensuring safety, 2) economic competitiveness, 3) efficient utilization of resources, 4) reduction of environmental load and 5) enhancement of nuclear non-proliferation. Based on the selection of the promising concepts in the first phase, conceptual design for the plant system has proceeded with the following plant system: a) sodium cooled reactors at large size and medium size module reactors, b) a lead-bismuth cooled medium size reactor, c) a helium gas cooled large size reactor and d) a BWR type large size FBR. Technical development and feasibility has been assessed and the study considers the need of respective key technology development for the confirmation of the feasibility study. (T. Tanaka)

  10. Study protocol: the empirical investigation of methods to correct for measurement error in biobanks with dietary assessment

    Directory of Open Access Journals (Sweden)

    Masson Lindsey F

    2011-10-01

    Full Text Available Abstract Background The Public Population Project in Genomics (P3G is an organisation that aims to promote collaboration between researchers in the field of population-based genomics. The main objectives of P3G are to encourage collaboration between researchers and biobankers, optimize study design, promote the harmonization of information use in biobanks, and facilitate transfer of knowledge between interested parties. The importance of calibration and harmonisation of methods for environmental exposure assessment to allow pooling of data across studies in the evaluation of gene-environment interactions has been recognised by P3G, which has set up a methodological group on calibration with the aim of; 1 reviewing the published methodological literature on measurement error correction methods with assumptions and methods of implementation; 2 reviewing the evidence available from published nutritional epidemiological studies that have used a calibration approach; 3 disseminating information in the form of a comparison chart on approaches to perform calibration studies and how to obtain correction factors in order to support research groups collaborating within the P3G network that are unfamiliar with the methods employed; 4 with application to the field of nutritional epidemiology, including gene-diet interactions, ultimately developing a inventory of the typical correction factors for various nutrients. Methods/Design Systematic review of (a the methodological literature on methods to correct for measurement error in epidemiological studies; and (b studies that have been designed primarily to investigate the association between diet and disease and have also corrected for measurement error in dietary intake. Discussion The conduct of a systematic review of the methodological literature on calibration will facilitate the evaluation of methods to correct for measurement error and the design of calibration studies for the prospective pooling of

  11. Investigating the Experiences of Childhood Cancer Patients and Parents Participating in Optional Nontherapeutic Clinical Research Studies in the UK.

    Science.gov (United States)

    Errington, Julie; Malik, Ghada; Evans, Julie; Baston, Jenny; Parry, Annie; Price, Lisa; Johnstone, Hina; Peters, Selena; Oram, Victoria; Howe, Karen; Whiteley, Emma; Tunnacliffe, Jane; Veal, Gareth J

    2016-07-01

    While the majority of childhood cancer clinical trials are treatment related, additional optional research investigations may be carried out that do not directly impact on treatment. It is essential that these studies are conducted ethically and that the experiences of families participating in these studies are as positive as possible. A questionnaire study was carried out to investigate the key factors that influence why families choose to participate in optional nontherapeutic research studies, the level of understanding of the trials involved, and the experiences of participation. A total of 100 participants from six UK centers were studied; 77 parents, 10 patients >16 years, and 13 patients aged 8-15 years. Ninety-seven percent of parents and 90% of patients felt that information provided prior to study consent was of the right length, with 52% of parents and 65% of patients fully understanding the information provided. Seventy-four percent of parents participated in research studies in order to "do something important", while 74% of patients participated "to help medical staff". Encouragingly, <5% of participants felt that their clinical care would be negatively affected if they did not participate. Positive aspects of participation included a perception of increased attention from medical staff. Negative aspects included spending longer periods in hospital and the requirement for additional blood samples. Ninety-six percent of parents and 87% of patients would participate in future studies. The study provides an insight into the views of childhood cancer patients and their parents participating in nontherapeutic clinical research studies. Overwhelmingly, the findings suggest that participation is seen as a positive experience. © 2016 The Authors. Pediatric Blood & Cancer, published by Wiley Periodicals, Inc.

  12. Investigative psychology

    OpenAIRE

    Canter, David V.

    2010-01-01

    The domain of Investigative Psychology covers all aspects of psychology that are relevant to the conduct of criminal or civil investigations. Its focus is on the ways in which criminal activities may be examined and understood in order for the detection of crime to be effective and legal proceedings to be appropriate. As such Investigative Psychology is concerned with psychological input to the full range of issues that relate to the management, investigation and prosecution of crime

  13. Paleontology investigations aided by medical radiology

    International Nuclear Information System (INIS)

    Lansu, M.J.; Carpenter, K.; Albano, J.; Meals, R.; Brady, L.W.

    1987-01-01

    Medical radiology instruments provide useful tools for nondestructive investigations in other scientific fields. To date, 15 paleontology specimens have been studied using conventional diagnostic units, therapy simulators, and CT scanners. Most specimens, individual marine animals or large dinosaur heads, needed a combination of studies to complete the investigation. Among the results shown are the inner ear of a Plesiosaurus, which is 76 million years old, and a pearl attached to an extinct clam species, which is 1 million years old. The results confirm the usefulness of radiology as a tool in the field of paleontology

  14. A Phenomenological Study Investigating Transformative Learning Strategies Implemented by 10 Title I Elementary Principals That Influence Novice Teacher Retention

    Science.gov (United States)

    Fountain, Tara

    2014-01-01

    The purpose of this qualitative phenomenological study was to investigate transformative learning strategies implemented by 10 Title I elementary principals that influence novice teacher retention. Data were gathered by individual interviews. Data were analyzed using Creswell's (2013) description of qualitative research as a collection of data…

  15. A retrospective study to investigate racial and ethnic variations in the treatment of psoriasis with etanercept.

    Science.gov (United States)

    Shah, Sejal K; Arthur, Angele; Yang, Yu-Ching; Stevens, Seth; Alexis, Andrew F

    2011-08-01

    Psoriasis is a chronic inflammatory condition that occurs worldwide; however, few studies have examined this condition in non-Caucasian populations. The purpose of this study was to investigate racial/ethnic differences in demographics, psoriasis severity, efficacy, safety, and health-related quality of life in patients treated with etanercept using data from the Etanercept Assessment of Safety and Effectiveness (EASE) in Psoriasis trial. This is an investigator-initiated evaluation of data from the EASE study. The study included 2511 patients (Caucasian n=2164; Hispanic/Latino n=173; African American n=98; Asian n=76). Although baseline Physicians' Global Assessment (PGA) scores were similar, we found significant baseline differences in patient characteristics, prior therapy, percentage of body surface area (%BSA) affected and Dermatology Life Quality Index (DLQI) scores between the groups. At baseline, the Caucasian group had the longest disease duration (19 years), but the lowest percentage of BSA involvement (28%). The Asian group had the highest percentage of BSA involvement (41%). Baseline DLQI score was lowest for Caucasians (12.0) and highest for Hispanic/Latinos (14.6). At week 12, response to therapy was similar in all ethnic/racial groups. The BSA involvement was reduced by more than 50 percent for all groups, but remained significantly higher for the Asian group (17%) than for the Caucasian (13%; P=0.0105) and African American groups (13%; P=0.0461). At week 12, the mean Asian DLQI score of 5.2 was significantly higher (worse) than scores for the Caucasian (3.5; P=0.0001) and Hispanic/Latino groups (3.8; P=0.028). For both percentage of BSA and DLQI, differences among racial/ethnic groups in the percentage improvement from baseline were not statistically significant. Adverse event rates were similar for the groups. Patient characteristics at enrollment differed among ethnic groups, but no significant racial/ethnic differences were found in safety or

  16. Remedial investigation/feasibility study for the Clinch River/Poplar Creek operable unit. Volume 4. Appendix F

    International Nuclear Information System (INIS)

    1995-09-01

    This section contains ecotoxicological profiles for the COPECs for the combined Remedial Investigation/Feasibility Study Report for the Clinch River/Poplar Crack (CR/PC) Operable Unit (OU). The ecotoxicological information is presented for only those endpoints for which the chemicals are COPECs. The CR/PC OU is located in Anderson and Roane Counties, Tennessee and consists of the Clinch River and several of its embayments in Melton Hill and Watts Bar Reservoirs. These waters have received hazardous substances released over a period of 50 years from the US Department of Energy's Oak Ridge Reservation (ORR), a National Priority List site established under the Comprehensive Environmental Response, Compensation, and Liability Act. A remedial investigation has been conducted to determine the current nature and extent of any contamination and to assess the resulting risk to human health and the environment. The feasibility study evaluates remedial action alternatives to identify any that are feasible for implementation and that would effectively reduce risk. Historical studies had indicated that current problems would likely include 137 Cs in sediment of the Clinch River, mercury in sediment and fish of Poplar Creek and PCBs and pesticides in fish from throughout the OU. Peak releases of mercury and 137 Cs occurred over 35 years ago, and current releases are low. Past releases of PCBs from the ORR are poorly quantified, and current releases are difficult to quantify because levels are so low. The site characterization focused on contaminants in surface water, sediment, and biota. Contaminants in surface water were all found to be below Ambient Water Quality Criteria. Other findings included the following: elevated metals including cesium 137 and mercury in McCoy Branch sediments; PCBs and chlordane elevated in several fish species, presenting the only major human health risk, significant ecological risks in Poplar Creek but not in the Clinch River

  17. Remedial investigation/feasibility study for the Clinch River/Poplar Creek operable unit. Volume 4. Appendix F

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-09-01

    This section contains ecotoxicological profiles for the COPECs for the combined Remedial Investigation/Feasibility Study Report for the Clinch River/Poplar Crack (CR/PC) Operable Unit (OU). The ecotoxicological information is presented for only those endpoints for which the chemicals are COPECs. The CR/PC OU is located in Anderson and Roane Counties, Tennessee and consists of the Clinch River and several of its embayments in Melton Hill and Watts Bar Reservoirs. These waters have received hazardous substances released over a period of 50 years from the US Department of Energy`s Oak Ridge Reservation (ORR), a National Priority List site established under the Comprehensive Environmental Response, Compensation, and Liability Act. A remedial investigation has been conducted to determine the current nature and extent of any contamination and to assess the resulting risk to human health and the environment. The feasibility study evaluates remedial action alternatives to identify any that are feasible for implementation and that would effectively reduce risk. Historical studies had indicated that current problems would likely include {sup 137}Cs in sediment of the Clinch River, mercury in sediment and fish of Poplar Creek and PCBs and pesticides in fish from throughout the OU. Peak releases of mercury and {sup 137}Cs occurred over 35 years ago, and current releases are low. Past releases of PCBs from the ORR are poorly quantified, and current releases are difficult to quantify because levels are so low. The site characterization focused on contaminants in surface water, sediment, and biota. Contaminants in surface water were all found to be below Ambient Water Quality Criteria. Other findings included the following: elevated metals including cesium 137 and mercury in McCoy Branch sediments; PCBs and chlordane elevated in several fish species, presenting the only major human health risk, significant ecological risks in Poplar Creek but not in the Clinch River.

  18. Remedial investigation/feasibility study for the Clinch River/Poplar Creek operable unit. Volume 3. Appendix E

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-09-01

    This document contains Appendix E: Toxicity Information and Uncertainty Analysis, description of methods, from the combined Remedial Investigation/Feasibility Study Report for the Clinch River/Poplar Crack (CR/PC) Operable Unit (OU). The CR/PC OU is located in Anderson and Roane Counties, Tennessee and consists of the Clinch River and several of its embayments in Melton Hill and Watts Bar Reservoirs. These waters have received hazardous substances released over a period of 50 years from the US Department of Energy`s Oak Ridge Reservation (ORR), a National Priority List site established under the Comprehensive Environmental Response, Compensation, and Liability Act. A remedial investigation has been conducted to determine the current nature and extent of any contamination and to assess the resulting risk to human health and the environment. The feasibility study evaluates remedial action alternatives to identify any that are feasible for implementation and that would effectively reduce risk. Historical studies had indicated that current problems would likely include {sup 137}Cs in sediment of the Clinch River, mercury in sediment and fish of Poplar Creek and PCBs and pesticides in fish from throughout the OU. Peak releases of mercury and {sup 137}Cs occurred over 35 years ago, and current releases are low. Past releases of PCBs from the ORR are poorly quantified, and current releases are difficult to quantify because levels are so low. The site characterization focused on contaminants in surface water, sediment, and biota. Contaminants in surface water were all found to be below Ambient Water Quality Criteria. Other findings included the following: elevated metals including cesium 137 and mercury in McCoy Branch sediments; PCBs and chlordane elevated in several fish species, presenting the only major human health risk, significant ecological risks in Poplar Creek but not in the Clinch River.

  19. Remedial investigation/feasibility study for the Clinch River/Poplar Creek operable unit. Volume 1. Main text

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-09-01

    This is the combined Remedial Investigation/Feasibility Study Report for the Clinch River/Poplar Crack (CR/PC) Operable Unit (OU). The CR/PC OU is located in Anderson and Roane Counties, Tennessee and consists of the Clinch River and several of its embayments in Melton Hill and Watts Bar Reservoirs. These waters have received hazardous substances released over a period of 50 years from the US Department of Energy`s Oak Ridge Reservation (ORR), a National Priority List site established under the Comprehensive Environmental Response, Compensation, and Liability Act. A remedial investigation has been conducted to determine the current nature and extent of any contamination and to assess the resulting risk to human health and the environment. The feasibility study evaluates remedial action alternatives to identify any that are feasible for implementation and that would effectively reduce risk. Historical studies had indicated that current problems would likely include {sup 137}Cs in sediment of the Clinch River, mercury in sediment and fish of Poplar Creek and PCBs and pesticides in fish from throughout the OU. Peak releases of mercury and {sup 137}Cs occurred over 35 years ago, and current releases are low. Past releases of PCBs from the ORR are poorly quantified, and current releases are difficult to quantify because levels are so low. The site characterization focused on contaminants in surface water, sediment, and biota. Contaminants in surface water were all found to be below Ambient Water Quality Criteria. Other findings included the following: elevated metals including cesium 137 and mercury in McCoy Branch sediments; PCBs and chlordane elevated in several fish species, presenting the only major human health risk, significant ecological risks in Poplar Creek but not in the Clinch River.

  20. Remedial investigation/feasibility study for the Clinch River/Poplar Creek operable unit. Volume 3. Appendix E

    International Nuclear Information System (INIS)

    1995-09-01

    This document contains Appendix E: Toxicity Information and Uncertainty Analysis, description of methods, from the combined Remedial Investigation/Feasibility Study Report for the Clinch River/Poplar Crack (CR/PC) Operable Unit (OU). The CR/PC OU is located in Anderson and Roane Counties, Tennessee and consists of the Clinch River and several of its embayments in Melton Hill and Watts Bar Reservoirs. These waters have received hazardous substances released over a period of 50 years from the US Department of Energy's Oak Ridge Reservation (ORR), a National Priority List site established under the Comprehensive Environmental Response, Compensation, and Liability Act. A remedial investigation has been conducted to determine the current nature and extent of any contamination and to assess the resulting risk to human health and the environment. The feasibility study evaluates remedial action alternatives to identify any that are feasible for implementation and that would effectively reduce risk. Historical studies had indicated that current problems would likely include 137 Cs in sediment of the Clinch River, mercury in sediment and fish of Poplar Creek and PCBs and pesticides in fish from throughout the OU. Peak releases of mercury and 137 Cs occurred over 35 years ago, and current releases are low. Past releases of PCBs from the ORR are poorly quantified, and current releases are difficult to quantify because levels are so low. The site characterization focused on contaminants in surface water, sediment, and biota. Contaminants in surface water were all found to be below Ambient Water Quality Criteria. Other findings included the following: elevated metals including cesium 137 and mercury in McCoy Branch sediments; PCBs and chlordane elevated in several fish species, presenting the only major human health risk, significant ecological risks in Poplar Creek but not in the Clinch River

  1. Magnetic resonance imaging investigation of the bone conduction implant - a pilot study at 1.5 Tesla.

    Science.gov (United States)

    Jansson, Karl-Johan Fredén; Håkansson, Bo; Reinfeldt, Sabine; Rigato, Cristina; Eeg-Olofsson, Måns

    2015-01-01

    The objective of this pilot study was to investigate if an active bone conduction implant (BCI) used in an ongoing clinical study withstands magnetic resonance imaging (MRI) of 1.5 Tesla. In particular, the MRI effects on maximum power output (MPO), total harmonic distortion (THD), and demagnetization were investigated. Implant activation and image artifacts were also evaluated. One implant was placed on the head of a test person at the position corresponding to the normal position of an implanted BCI and applied with a static pressure using a bandage and scanned in a 1.5 Tesla MRI camera. Scanning was performed both with and without the implant, in three orthogonal planes, and for one spin-echo and one gradient-echo pulse sequence. Implant functionality was verified in-between the scans using an audio processor programmed to generate a sequence of tones when attached to the implant. Objective verification was also carried out by measuring MPO and THD on a skull simulator as well as retention force, before and after MRI. It was found that the exposure of 1.5 Tesla MRI only had a minor effect on the MPO, ie, it decreased over all frequencies with an average of 1.1±2.1 dB. The THD remained unchanged above 300 Hz and was increased only at lower frequencies. The retention magnet was demagnetized by 5%. The maximum image artifacts reached a distance of 9 and 10 cm from the implant in the coronal plane for the spin-echo and the gradient-echo sequence, respectively. The test person reported no MRI induced sound from the implant. This pilot study indicates that the present BCI may withstand 1.5 Tesla MRI with only minor effects on its performance. No MRI induced sound was reported, but the head image was highly distorted near the implant.

  2. Remedial investigation/feasibility study for the Clinch River/Poplar Creek operable unit. Volume 1. Main text

    International Nuclear Information System (INIS)

    1995-09-01

    This is the combined Remedial Investigation/Feasibility Study Report for the Clinch River/Poplar Crack (CR/PC) Operable Unit (OU). The CR/PC OU is located in Anderson and Roane Counties, Tennessee and consists of the Clinch River and several of its embayments in Melton Hill and Watts Bar Reservoirs. These waters have received hazardous substances released over a period of 50 years from the US Department of Energy's Oak Ridge Reservation (ORR), a National Priority List site established under the Comprehensive Environmental Response, Compensation, and Liability Act. A remedial investigation has been conducted to determine the current nature and extent of any contamination and to assess the resulting risk to human health and the environment. The feasibility study evaluates remedial action alternatives to identify any that are feasible for implementation and that would effectively reduce risk. Historical studies had indicated that current problems would likely include 137 Cs in sediment of the Clinch River, mercury in sediment and fish of Poplar Creek and PCBs and pesticides in fish from throughout the OU. Peak releases of mercury and 137 Cs occurred over 35 years ago, and current releases are low. Past releases of PCBs from the ORR are poorly quantified, and current releases are difficult to quantify because levels are so low. The site characterization focused on contaminants in surface water, sediment, and biota. Contaminants in surface water were all found to be below Ambient Water Quality Criteria. Other findings included the following: elevated metals including cesium 137 and mercury in McCoy Branch sediments; PCBs and chlordane elevated in several fish species, presenting the only major human health risk, significant ecological risks in Poplar Creek but not in the Clinch River

  3. An Ongoing Investigation of Science Literacy: Results of a 22-Year Study Probing Students' Knowledge and Attitude Towards Science

    Science.gov (United States)

    Impey, C.; Buxner, S.; Antonellis, J.; CATS

    2013-04-01

    This talk presents findings related to our ongoing work investigating students' knowledge and attitudes towards science and technology. We present an overview of research studies and findings including a comparison of the science literacy measures of University of Arizona students compared to national studies, conceptions related to astrology, views of radiation, and students' pseudoscience and religious beliefs. We discuss implications for instructors and researchers interested in improving students' science literacy scores and diagnosing alternative beliefs.

  4. Studying global change through investigation of the plastic responses of xylem anatomy in tree rings.

    Science.gov (United States)

    Fonti, Patrick; von Arx, Georg; García-González, Ignacio; Eilmann, Britta; Sass-Klaassen, Ute; Gärtner, Holger; Eckstein, Dieter

    2010-01-01

    Variability in xylem anatomy is of interest to plant scientists because of the role water transport plays in plant performance and survival. Insights into plant adjustments to changing environmental conditions have mainly been obtained through structural and functional comparative studies between taxa or within taxa on contrasting sites or along environmental gradients. Yet, a gap exists regarding the study of hydraulic adjustments in response to environmental changes over the lifetimes of plants. In trees, dated tree-ring series are often exploited to reconstruct dynamics in ecological conditions, and recent work in which wood-anatomical variables have been used in dendrochronology has produced promising results. Environmental signals identified in water-conducting cells carry novel information reflecting changes in regional conditions and are mostly related to short, sub-annual intervals. Although the idea of investigating environmental signals through wood anatomical time series goes back to the 1960s, it is only recently that low-cost computerized image-analysis systems have enabled increased scientific output in this field. We believe that the study of tree-ring anatomy is emerging as a promising approach in tree biology and climate change research, particularly if complemented by physiological and ecological studies. This contribution presents the rationale, the potential, and the methodological challenges of this innovative approach.

  5. Investigating reading comprehension through EEG

    Directory of Open Access Journals (Sweden)

    Luciane Baretta

    2012-12-01

    Full Text Available http://dx.doi.org/10.5007/2175-8026.2012n63p69   Experimental studies point that different factors can influence reading comprehension, such as the topic, text type, reading task, and others. The advances in technologies for the past decades have provided researchers with several possibilities to investigate what goes on in one’s brain since their eyes meet the page until comprehension is achieved. Since the mid-80’s, numerous studies have been conducted with the use of the electroencephalogram (EEG to investigate the process of reading, through the analysis of different components – n400, n100 or n1, P2, among others. These components reveal, for example, how the brain integrates the meaning of a specific word in the semantic context of a given sentence.  based on previous studies, which demonstrate that different types of words affect cognitive load, this paper aims at investigating how the brain processes function and content words inserted in expository and narrative texts with suitable / unsuitable conclusions. results showed that the type of text and word influence the cognitive load in different scalp areas (midline, right and left hemispheres. The  n1s were more pronounced to the content words inserted in narrative texts and to the function words inserted in the expository type of texts, corroborating former studies.

  6. STRUCTURAL STUDY AND INVESTIGATION OF NMR TENSORS ...

    African Journals Online (AJOL)

    NBO studies were performed to the second-order and perturbative estimates of donor-acceptor interaction have been done. The procedures of gauge-invariant atomic orbital (GIAO) and continuous-set-of-gauge-transformation (CSGT) were employed to calculate isotropic shielding, chemical shifts anisotropy and chemical ...

  7. Synthesis, structure, spectroscopic investigations, and computational studies of optically pure β-ketoamide

    Energy Technology Data Exchange (ETDEWEB)

    Mtat, D.; Touati, R. [Université de Monastir, Laboratoire de Synthèse Organique Asymétrique et Catalyse Homogène (UR11ES56), Faculté des Sciences (Tunisia); Guerfel, T., E-mail: taha-guerfel@yahoo.fr [Université de Kairouan, Laboratoire d’Electrochimie, Matériaux et Environnement (Tunisia); Walha, K. [Université de Sfax, M.E.S.Lab. Faculté des Sciences de Sfax (Tunisia); Ben Hassine, B. [Université de Monastir, Laboratoire de Synthèse Organique Asymétrique et Catalyse Homogène (UR11ES56), Faculté des Sciences (Tunisia)

    2016-12-15

    Chemical preparation, X-ray single crystal diffraction, IR and NMR spectroscopic investigations of a novel nonlinear optical organic compound (C{sub 17}H{sub 22}NO{sub 2}Cl) are described. The compound crystallizes in the orthorhombic system with the non-centrosymmetric sp. gr. P2{sub 1}2{sub 1}2{sub 1}. In the crystal structure, molecules are interconnected by N–H…O hydrogen bonds forming infinite chains along a axis. The Hirshfeld surface and associated fingerprint plots of the compound are presented to explore the nature of intermolecular interactions and their relative contributions in building the solid-state architecture. The molecular HOMO–LUMO compositions and their respective energy gaps are also drawn to explain the activity of the compound. The first hyperpolarizability β{sub tot} of the title compound is determined using DFT calculations. The optical properties are also investigated by UV–Vis absorption spectrum.

  8. Site investigations. Investigation methods and general execution programme

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-01-01

    SKB plans to commence site investigations in 2002. The present report is a broadening of the general programme and describes the execution of the investigations in so-called discipline-specific programmes for the disciplines geology, rock mechanics, thermal properties, hydrogeology, hydro geochemistry, transport properties of the rock and surface ecosystems. It also describes various technical aspects of drilling, which comprises a significant portion of the investigations. Based on this possible programme, site-specific programmes will then be prepared and adapted to the site-specific questions and conditions on the specific candidate area. The main product of the investigations is a site description. This document presents an integrated description of the site (geosphere and biosphere) and its regional environs with respect to current state and naturally ongoing processes. Provided that the initial site investigation shows that the site is still favourable, complete investigations are commenced. Primary investigation data are stored in SKB's database SICADA. The database's primary data mainly represent parameter values for single measurement points or limited measurement objects. Primary data are subjected to both discipline-specific and integrated analysis and interpretation in order to be able to subdivide the site into suitable geometric units and to assign discipline-specific properties to these geometric units. In this way a three-dimensional, primarily geo scientific, site-descriptive model of rock and ground is built. The site-descriptive model is represented with the aid of both geographic information systems (GIS) and above all SKB's CAD-based computer tool, Rock Visualization System (RVS). RVS is also used as an active instrument in the interpretation of information, especially to be able to judge the relative locations of different deformation zones. When the site has been selected, the investigations are focused on characterizing

  9. AN INVESTIGATIVE STUDY REGARDING SMES SPECIFIC ACCOUNTING POLICIES

    Directory of Open Access Journals (Sweden)

    Mester Ioana Teodora

    2011-07-01

    Full Text Available In this paper we intend to continue the research regarding the enterprise accounting policies and the manner in which these are perceived by the practitioner accountants, preparers of financial statements. This time, in order to carry out the research, we made up a new questionnaire applied to the same sample, containing a number of 100 SMEs in Bihor County, selected according to the criterion of the average number of employees and that of the level of net turnover at the end of 2008. Continuing previous conducted research we have investigated this time the specific accounting policies of the sampled SMEs from Bihor County and the way these policies are understood by practitioners and implemented in order to prepare financial statements. Surprisingly, we have found that only 93.33% of the respondents agree that the elements presented in the annual financial statements of the entity are evaluated in accordance with the general accounting principles stipulated in Order 3055/2009, according to the accrual accounting. Half of the people interviewed had in view all four qualities of accounting information (intelligibility, relevance, credibility, comparability in drawing up the annual financial statements, and most of them (56.67% are not aware of the possibility to use a significance threshold (10%-15% of the total value of that particular category of assets, liabilities, expenditure, income and results for an as faithful as possible presentation of information in the balance sheet and in the profit and loss account.

  10. Charles Darwin's Botanical Investigations

    Science.gov (United States)

    Harley, Suzanne M.

    2010-01-01

    Charles Darwin's botanical studies provide a way to expose students to his work that followed the publication of "On the Origin of Species." We can use stories from his plant investigations to illustrate key concepts in the life sciences and model how questions are asked and answered in science.

  11. Remedial investigation/feasibility study of the Clinch River/Poplar Creek operable unit. Volume 4. Information related to the feasibility study and ARARs. Appendixes G, H, I

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    This report presents the findings of an investigation into contamination of the Clinch River and Poplar Creek near the U.S. Department of Energy`s (DOE`s) Oak Ridge Reservation (ORR) in eastern Tennessee. For more than 50 years, various hazardous and radioactive substances have been released to the environment as a result of operations and waste management activities at the ORR. In 1989, the ORR was placed on the National Priorities List (NPL), established and maintained under the federal Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). Under CERCLA, NPL sites must be investigated to determine the nature and extent of contamination at the site, assess the risk to human health and the environment posed by the site, and, if necessary, identify feasible remedial alternatives that could be used to clean the site and reduce risk. To facilitate the overall environmental restoration effort at the ORR, CERCLA activities are being implemented individually as distinct operable units (OUs). This document is the combined Remedial Investigation and Feasibility Study Report for the Clinch River/Poplar Creek OU.

  12. Investigating the psychosocial determinants of child health in Africa: the Drakenstein Child Health Study

    Science.gov (United States)

    Stein, DJ; Koen, N; Donald, KA; Adnams, CM; Koopowitz, S; Lund, C; Marais, A; Myers, B; Roos, A; Sorsdahl, K; Stern, M; Tomlinson, M; van der Westhuizen, C; Vythilingum, B; Myer, L; Barnett, W; Brittain, K; Zar, HJ

    2015-01-01

    Background Early life psychobiological and psychosocial factors play a key role in influencing child health outcomes. Longitudinal studies may help elucidate the relevant risk and resilience profiles, and the underlying mechanisms that impact on child health, but there is a paucity of birth cohort data from low and middle-income countries (LMIC). We describe the rationale for and present baseline findings from the psychosocial component of the Drakenstein Child Health Study (DCHS). Methods We review the psychosocial measures used in the DCHS, a multidisciplinary birth cohort study in a peri-urban area in South Africa, and provide initial data on psychological distress, depression, substance use, and exposure to traumatic stressors and intimate partner violence (IPV). These and other measures will be assessed longitudinally in mothers in order to investigate associations with child neurodevelopmental and health outcomes. Results Baseline psychosocial data is presented for mothers (n = 634) and fathers (n = 75) who have completed antenatal assessments to date. The sample of pregnant mothers is characterized by multiple psychosocial risk factors, including a high prevalence of psychological distress and depression, high levels of substance use, and high exposure to traumatic stressors and IPV. Discussion These data are consistent with prior South African studies which have documented a high prevalence of a multitude of risk factors during pregnancy. Further longitudinal assessment of mothers and children may clarify the underlying psychobiological and psychosocial mechanisms which impact on child health, and so inform clinical and public health interventions appropriate to the South African and other LMIC contexts. PMID:25797842

  13. Preliminary results of ERTS-investigations by W-German investigations. [multidisciplinary geoscientific experiments in central Germany and hydrogeology of Argentina Pampas

    Science.gov (United States)

    Muehlfeld, R.

    1974-01-01

    Results are presented of West German investigations into multidisciplinary geoscientific experiments in central Germany and the Alps, and hydrogeological investigations in the Pampa of Argentina based on ERTS-1 data. The main goals of the investigation were achieved. The studies have given a good idea of the possibilities and limitations of ERTS imagery depending on the objectives in question and on the geographical conditions of the areas under investigation. Even in the well known region of central Europe, ERTS has proven its ability of improving present knowledge. In fields such as pollution monitoring and regional planning the satellite techniques should have distinct practical value. For any regional study of less known areas, the value of ERTS imagery can hardly be overestimated.

  14. Investigating Student Attitudes toward Augmented Reality

    Science.gov (United States)

    Sirakaya, Mustafa; Kiliç Çakmak, Ebru

    2018-01-01

    This study aimed at identifying the attitudes of secondary school students toward AR applications and to investigate the change in these attitudes according to different variables. The study also aspired to determine the relationship between attitudes toward AR and achievement. The general survey model was used in the study. The study group was…

  15. Endogenous versus exogenous exposure to N-nitroso compounds and gastric cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST) study.

    NARCIS (Netherlands)

    Jakszyn, Paula; Bingham, Sheila A; Pera, Guillem; Agudo, Antonio; Luben, Robert; Welch, Ailsa; Boeing, Heiner; Giudice, Giuseppe del; Palli, Domenico; Saieva, Calogero; Krogh, Vittorio; Sacerdote, Carlotta; Tumino, Rosario; Panico, Salvatore; Berglund, Göran; Simán, Henrik; Hallmans, Göran; Sanchez, María José; Larrañaga, Nerea; Barricarte, Aurelio; Chirlaque, María-Dolores; Quirós, José Ramón; Key, Timothy J; Allen, Naomi E; Lund, Eiliv; Carneiro, Fátima; Linseisen, Jakob; Nagel, Gabriele; Overvad, Kim; Tjønneland, Anne; Olsen, Anja; Bueno-de-Mesquita, H Bas; Ocké, Marga C; Peeters, Petra H M; Numans, Mattijs E; Clavel-Chapelon, Françoise; Trichopoulou, Antonia; Fenger, Claus; Stenling, Roger; Ferrari, Pietro; Jenab, Mazda; Norat, Teresa; Riboli, Elio; González, Carlos Alberto

    2006-01-01

    The risk of gastric cancer (GC) associated with dietary intake of nitrosodimethylamine (NDMA) and endogenous formation of nitroso compounds (NOCs) was investigated in the European Prospective Investigation into Cancer and Nutrition (EPIC). The study included 521,457 individuals and 314 incident

  16. Endogenous versus exogenous exposure to N-Nitroso compounds and gastric cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST) study.

    NARCIS (Netherlands)

    Jakszyn, P.; Bingham, S.; Pera, G.; Agudo, A.; Luben, R.; Welch, A.; Boeing, H.; Giudice, G. del; Palli, D.; Saieva, C.; Krogh, V.; Sacerdote, C.; Tumino, R.; Panico, S.; Berglund, G.; Simán, H.; Hallmans, G.; Sanchez, M.J.; Larrañaga, N.; Barricarte, A.; Chirlaque, M.D.; Quirós, J.R.; Key, T.J.; Allen, N.; Lund, E.; Carneiro, F.; Linseisen, J.; Nagel, G.; Overvad, K.; Tjønneland, A.; Olsen, A.; Bueno-de-Mesquita, H.B.; Ocké, M.O.; Peeters, P.H.M.; Numans, M.E.; Clavel-Chapelon, F.; Trichopoulou, A.; Fenger, C.; Stenling, R.; Ferrari, P.; Jenab, M.; Norat, T.; Riboli, E.; Gonzalez, C.A.

    The risk of gastric cancer (GC) associated with dietary intake of Nitrosodimethylamine (NDMA) and endogenous formation of Nitroso compounds (NOCs) was investigated in the European Prospective Investigation into Cancer and Nutrition (EPIC). The study included 521,457 individuals and 314 incident

  17. A clinical study on the investigation of the cause of a patient's death after cardiopulmonary arrest on arrival

    International Nuclear Information System (INIS)

    Kato, Akihito; Sato, Keizo; Fujishiro, Masaya

    2011-01-01

    The investigation of the cause of a patient's death after cardiopulmonary arrest (CPA) on arrival usually requires an autopsy. In most areas in Japan, however, such an autopsy is rarely performed, except for those areas with a medical examiner system. No reports demonstrating how to investigate the cause of the patient's death after CPA on arrival were found to our knowledge. From September 1, 2007 to August 31, 2010, 1121 CPA patients died in spite of cardiopulmonary resuscitation in the Emergency and Critical Care Center at Showa University Fujigaoka Hospital. In this paper, causes of their death were reexamined using medical records, roentgenograms of their chest and abdomen in addition to computed tomography (CT) films when taken. Further, the means by which to investigate the cause of death was studied. The detailed reexamination resulted in the estimation for causes of 652 (58.2%) patients' death as follows: 67 cardiac, 61 aortic, 75 respiratory, 44 cerebral, 25 alimentary, 20 renal, 57 systemic diseases and 303 external deaths. Causes of 469 (41.8%) patients' death were unknown. Although CT examination was performed for 219 patients (26.0%), the cause of 75 patient deaths could not be estimated. Reexaminations of medical records revealed 379 prodromes of 300 CPA patients (26.8%), but no prodromes indicated any specific disease. Anamneses were partly useful for specifying causes of their death. On the other hand, CT examinations were highly useful for not only diagnosing the specific disease but also denying it. Even when causes of their death could not be specified, reexaminations of both CT findings and other clinical data resulted in possible diagnoses of the disease for most cases. The spread of a medical examiner system throughout Japan is the most desirable for investigating causes of CPA patients' death. The postmortem CT examination seems to be preferable for such an investigation. (author)

  18. Using Occupational Safety and Health Administration accident investigations to study patterns in work fatalities.

    Science.gov (United States)

    Mendeloff, J M; Kagey, B T

    1990-11-01

    Investigations of fatalities by the Occupational Safety and Health Administration (OSHA) provide the most detailed available information about traumatic workplace deaths that are potentially related to violations of existing safety standards. Comparison of the number of such deaths investigated by OSHA from 1977 to 1986 with the comparable category of deaths reported to the Bureau of Labor Statistics Survey of Occupational Injuries and Illnesses indicates that the overall magnitudes have been roughly similar. The OSHA data contain more information than other sources and are especially valuable for analyses of fatalities at smaller workplaces. The OSHA data show that death rates decline sharply with establishment size; the inverted "U" pattern for lost workday injury rates is absent. Because accident investigations are conducted as part of an administrative system, the OSHA data can be influenced by changes in administrative policies. Changes over time in the percent of fatalities in which violations of OSHA standards were cited have clearly been influenced by changes in OSHA citation policy and thus do not provide a valid measure of the rate of violation-caused deaths. Realization of the epidemiological value of this data source depends upon a commitment from OSHA to maintain consistency in investigating accidents and to improve its data collection methods.

  19. Pilot Study: Colostomy and Urine Collection Protocol for Investigating Potential Inciting Causes of Hen Diuresis Syndrome.

    Science.gov (United States)

    Jones, Kelli; Turner, Bradley; Brandão, João; Hubbard, Sue Ann; Magee, Danny; Baughman, Brittany; Wills, Robert; Tully, Thomas

    2015-06-01

    Hen diuresis syndrome has emerged over the past 5 yr as a significant cause of mortality in the U.S. broiler breeder industry. The condition affects hens in production and is characterized by transient muscle weakness in the vent region, transient diuresis, and often urate deposits on the skin below the vent. Affected hens are often seen straining to lay an egg, which suggests oviduct contraction is also impaired. Related hen mortality, often reaching 1% or more a week, is believed to be primarily the result of male aggression of the vent region (Turner et al., "Investigating Causes of Excessive Urate Production in Broiler Breeder Hens Associated with Peritonitis and Cannibalism Mortality," Oral Presentation at The American Association of Avian Pathologists Annual Meeting, p. 139, 2010). The exact association between the cause of mortality and this syndrome is unknown, but it may be the consequence of transient partial to full oviduct prolapse, which predisposes or stimulates cannibalism and aggression. Based on unpublished work done prior to this study (Turner et al., ibid.), the evidence suggests the underlying problem is metabolic. We feel that urine collection and analysis is an essential component to understanding this condition. This study serves as a pilot study for future investigations that attempt to identify the nature and cause of the metabolic disturbance through paired urine and serum collection and analysis. For the purpose of this study, a small sample of 10 affected and 10 unaffected birds was used for sample collection. In order to collect pure urine, the birds were surgically colostomized. Colostomy did prove to be a useful means of collecting urine free of feces, and for the purposes of our study it yielded adequate urine samples for analysis. There were statistically relevant urine values observed. Affected birds had a higher presence of blood in the urine, a lower uric acid excretion rate (mg/hr), higher concentration (mEq/L) of urine Na+, and

  20. Vibrational, NMR and UV-visible spectroscopic investigation and NLO studies on benzaldehyde thiosemicarbazone using computational calculations

    Science.gov (United States)

    Moorthy, N.; Prabakar, P. C. Jobe; Ramalingam, S.; Pandian, G. V.; Anbusrinivasan, P.

    2016-04-01

    In order to investigate the vibrational, electronic and NLO characteristics of the compound; benzaldehyde thiosemicarbazone (BTSC), the XRD, FT-IR, FT-Raman, NMR and UV-visible spectra were recorded and were analysed with the calculated spectra by using HF and B3LYP methods with 6-311++G(d,p) basis set. The XRD results revealed that the stabilized molecular systems were confined in orthorhombic unit cell system. The cause for the change of chemical and physical properties behind the compound has been discussed makes use of Mulliken charge levels and NBO in detail. The shift of molecular vibrational pattern by the fusing of ligand; thiosemicarbazone group with benzaldehyde has been keenly observed. The occurrence of in phase and out of phase molecular interaction over the frontier molecular orbitals was determined to evaluate the degeneracy of the electronic energy levels. The thermodynamical studies of the temperature region 100-1000 K to detect the thermal stabilization of the crystal phase of the compound were investigated. The NLO properties were evaluated by the determination of the polarizability and hyperpolarizability of the compound in crystal phase. The physical stabilization of the geometry of the compound has been explained by geometry deformation analysis.

  1. Investigating Adaptive Grieving Styles: A Delphi Study

    Science.gov (United States)

    Doughty, Elizabeth A.

    2009-01-01

    There has been an evolution in the understanding of the nature of grief since S. Freud's initial work, Mourning and Melancholia (1917/1953). Mental health practitioners and researchers have established new models to aid in the conceptualization and treatment of grief issues. The purpose of this study was to examine the opinions of experts in the…

  2. Execution programme for the initial site investigations at Simpevarp

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-10-01

    In the feasibility studies that were completed in 2001, eight sites were identified as potentially suitable for hosting a repository. All the identified sites meet the safety requirements with respect to bedrock conditions that could be checked at that time. The feasibility studies have revealed good potential when it comes to the technical and environmental aspects as well. Based on an integrated evaluation SKB proposed to start site investigations with test drillings at three sites; Simpevarp, Forsmark, and Tierp north. The site investigations have started at Simpevarp and Forsmark. The municipal council of Tierp rejected a site investigation in April 2002. The site investigations are divided into two main phases; initial and complete investigations. Initial Site Investigation is performed to identify the site within a specified area that is deemed to be most suitable for a deep repository and to determine whether the feasibility study's judgement of the suitability of the area holds up in the light of borehole data from repository depth. The Initial Site Investigation is expected to take about 3 years. If the assessment shows that the site has good potential to host a repository, Complete Site Investigation will follow for an expected duration of another 3 years. The purpose of the Complete Site Investigation is to gather all information required to select one of the sites as the main alternative and to apply for a permit for construction of the deep repository at that site. The site-specific programme gives an overview of the whole site investigation phase as well as a detailed description of the initial stage. The results of the initial investigations will determine whether Simpevarp is appropriate for further investigation, i.e. the Complete Site Investigation. This document summarizes the investigations that will be carried out at Simpevarp during the Initial Site Investigations. The document is a working document, which will be successively updated as

  3. Execution programme for the initial site investigations at Simpevarp

    International Nuclear Information System (INIS)

    2002-10-01

    In the feasibility studies that were completed in 2001, eight sites were identified as potentially suitable for hosting a repository. All the identified sites meet the safety requirements with respect to bedrock conditions that could be checked at that time. The feasibility studies have revealed good potential when it comes to the technical and environmental aspects as well. Based on an integrated evaluation SKB proposed to start site investigations with test drillings at three sites; Simpevarp, Forsmark, and Tierp north. The site investigations have started at Simpevarp and Forsmark. The municipal council of Tierp rejected a site investigation in April 2002. The site investigations are divided into two main phases; initial and complete investigations. Initial Site Investigation is performed to identify the site within a specified area that is deemed to be most suitable for a deep repository and to determine whether the feasibility study's judgement of the suitability of the area holds up in the light of borehole data from repository depth. The Initial Site Investigation is expected to take about 3 years. If the assessment shows that the site has good potential to host a repository, Complete Site Investigation will follow for an expected duration of another 3 years. The purpose of the Complete Site Investigation is to gather all information required to select one of the sites as the main alternative and to apply for a permit for construction of the deep repository at that site. The site-specific programme gives an overview of the whole site investigation phase as well as a detailed description of the initial stage. The results of the initial investigations will determine whether Simpevarp is appropriate for further investigation, i.e. the Complete Site Investigation. This document summarizes the investigations that will be carried out at Simpevarp during the Initial Site Investigations. The document is a working document, which will be successively updated as

  4. Event Investigation

    International Nuclear Information System (INIS)

    Korosec, D.

    2000-01-01

    The events in the nuclear industry are investigated from the license point of view and from the regulatory side too. It is well known the importance of the event investigation. One of the main goals of such investigation is to prevent the circumstances leading to the event and the consequences of the event. The protection of the nuclear workers against nuclear hazard, and the protection of general public against dangerous effects of an event could be achieved by systematic approach to the event investigation. Both, the nuclear safety regulatory body and the licensee shall ensure that operational significant events are investigated in a systematic and technically sound manner to gather information pertaining to the probable causes of the event. One of the results should be appropriate feedback regarding the lessons of the experience to the regulatory body, nuclear industry and general public. In the present paper a general description of systematic approach to the event investigation is presented. The systematic approach to the event investigation works best where cooperation is present among the different divisions of the nuclear facility or regulatory body. By involving management and supervisors the safety office can usually improve their efforts in the whole process. The end result shall be a program which serves to prevent events and reduce the time and efforts solving the root cause which initiated each event. Selection of the proper method for the investigation and an adequate review of the findings and conclusions lead to the higher level of the overall nuclear safety. (author)

  5. Scientific Investigations of Elementary School Children

    Science.gov (United States)

    Valanides, Nicos; Papageorgiou, Maria; Angeli, Charoula

    2014-02-01

    The study provides evidence concerning elementary school children's ability to conduct a scientific investigation. Two hundred and fifty sixth-grade students and 248 fourth-grade students were administered a test, and based on their performance, they were classified into high-ability and low-ability students. The sample of this study was randomly selected and included 80 students, 40 fourth-grade and 40 sixth-grade students of low and high abilities. Students were specifically instructed to investigate the functioning of a device, to think aloud prior and after any experiment with the device, and to keep a record of their experimental results. The results showed that students were inclined to mainly collect evidence from the experimental space and failed to control variables during their investigation. The majority of the students had difficulties with effectively organizing collected data and failed to coordinate hypotheses with evidence. The significant interaction effect that was found between grade level and ability in terms of students' investigation ability indicates that the existing gap between high- and low-ability students becomes bigger as students become older. Undoubtedly, ongoing research efforts for identifying patterns of children's cognitive development will be most valuable as they can have important implications for the design of teaching scenarios and inquiry-based science activities conducive to accelerating students' cognitive growth and scientific investigation abilities.

  6. Investigating Inhibitory Control in Children with Epilepsy: An fMRI Study

    Science.gov (United States)

    Triplett, Regina L.; Velanova, Katerina; Luna, Beatriz; Padmanabhan, Aarthi; Gaillard, William D.; Asato, Miya R.

    2014-01-01

    SUMMARY Objective Deficits in executive function are increasingly noted in children with epilepsy and have been associated with poor academic and psychosocial outcomes. Impaired inhibitory control contributes to executive dysfunction in children with epilepsy; however, its neuroanatomic basis has not yet been investigated. We used functional Magnetic Resonance Imaging (fMRI) to probe the integrity of activation in brain regions underlying inhibitory control in children with epilepsy. Methods This cross-sectional study consisted of 34 children aged 8 to 17 years: 17 with well-controlled epilepsy and 17 age-and sex-matched controls. Participants performed the antisaccade (AS) task, representative of inhibitory control, during fMRI scanning. We compared AS performance during neutral and reward task conditions and evaluated task-related blood-oxygen level dependent (BOLD) activation. Results Children with epilepsy demonstrated impaired AS performance compared to controls during both neutral (non-reward) and reward trials, but exhibited significant task improvement during reward trials. Post-hoc analysis revealed that younger patients made more errors than older patients and all controls. fMRI results showed preserved activation in task-relevant regions in patients and controls, with the exception of increased activation in the left posterior cingulate gyrus in patients specifically with generalized epilepsy across neutral and reward trials. Significance Despite impaired inhibitory control, children with epilepsy accessed typical neural pathways as did their peers without epilepsy. Children with epilepsy showed improved behavioral performance in response to the reward condition, suggesting potential benefits of the use of incentives in cognitive remediation. PMID:25223606

  7. The remedial investigation/feasibility study process at Oak Ridge National Laboratory

    International Nuclear Information System (INIS)

    1993-01-01

    Martin Marietta Energy Systems, Inc. (Energy Systems), manages and operates the Oak Ridge National Laboratory (ORNL), Oak Ridge, Tennessee, under a cost-plus-award-fee contract administered by the Department of Energy's (DOE) Oak Ridge Field office (Field Office). Energy Systems' environmental restoration program is responsible for eliminating or reducing to prescribed safe levels the risks to the environment or to human health and safety posed by inactive and surplus sites and facilities that have been contaminated with radioactive, hazardous, or mixed wastes. Energy Systems subcontracted to perform the remedial investigation and feasibility study (RI/FS) at ORNL. The objective of our audit was to determine if the RI/FS at ORNL had been implemented in a manner that ensured accomplishment of the goals and objectives of the DOE Environmental Restoration Program. The audit disclosed that the subcontractor did not fully meet its contractual requirements. Specifically, environmental data produced by the subcontractor is of questionable value for meeting its contractual requirement to provide data supporting permanent remedial action. This condition occurred because neither the subcontractor nor Energy Systems adequately implemented all essential management controls, and neither Energy Systems nor DOE provided adequate contract administration. As a result, DOE has received little value for its RI/FS expenditures. We have recommended that DOE determine the allowability of an estimated $45 million of subcontractor RI/FS cost at ORNL, plus the cost of Energy Systems administering the subcontract. Furthermore, DOE will continue to pay unnecessary costs and experience cost growth and project delays until effective project management controls are implemented

  8. Characterization and Antibiofouling Performance Investigation of Hydrophobic Silver Nanocomposite Membranes: A Comparative Study.

    Science.gov (United States)

    Amouamouha, Maryam; Badalians Gholikandi, Gagik

    2017-11-12

    Biofouling is one of the drawbacks restricting the industrial applications of membranes. In this study, different thicknesses of silver nanoparticles with proper adhesion were deposited on poly(vinylidenefluoride) (PVDF) and polyethersulfone (PES) surfaces by physical vapor deposition (PVD). The crystalline and structural properties of modified and pure membranes were investigated by carrying out X-ray diffraction (XRD) and attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR). Scanning electron microscope (SEM) and atomic force microscopy (AFM) analyses were employed to examine the surface morphology and the bacteria anti-adhesion property of the membranes. The morphology measurements confirmed that even though after silver grafting the surface became more hydrophobic, the homogeneity increased and the flux reduction decreased after coating. Moreover a comparison between PVDF and PES revealed that CFU (colony forming units) reduced 64.5% on PVDF surface and 31.1% on PES surface after modification. In conclusion, PVD improved the performance of the membrane antibiofouling, and it is more promising to be used for PVDF rather than PES.

  9. Structural, vibrational, electronic investigations and quantum chemical studies of 2-amino-4-methoxybenzothiazole

    Science.gov (United States)

    Arjunan, V.; Raj, Arushma; Santhanam, R.; Marchewka, M. K.; Mohan, S.

    2013-02-01

    Extensive vibrational investigations of 2-amino-4-methoxybenzothiazole have been carried out with FTIR and FT-Raman spectral techniques. The electronic structure of the molecule has been analysed by UV-Visible and NMR spectroscopies. The DFT studies were carried out with B3LYP and HF methods utilising 6-31G(d,p), 6-311++G(d,p) and cc-pVDZ basis sets to determine the structural, thermodynamical, vibrational, electronic characteristics of the compound and also to understand the electronic and steric influence of the methoxy amino groups on the skeletal frequencies. The mixing of the fundamental modes was determined with the help of total energy distribution (TED). The energies of the frontier molecular orbitals have also been determined. The kinetic and thermodynamic stability and chemical hardness of the molecule have been determined. Complete NBO analysis was also carried out to find out the intramolecular electronic interactions and their stabilisation energy. 1H and 13C NMR chemical shifts and the electronic transitions of the molecule are also discussed.

  10. Characterization and Antibiofouling Performance Investigation of Hydrophobic Silver Nanocomposite Membranes: A Comparative Study

    Directory of Open Access Journals (Sweden)

    Maryam Amouamouha

    2017-11-01

    Full Text Available Biofouling is one of the drawbacks restricting the industrial applications of membranes. In this study, different thicknesses of silver nanoparticles with proper adhesion were deposited on poly(vinylidenefluoride (PVDF and polyethersulfone (PES surfaces by physical vapor deposition (PVD. The crystalline and structural properties of modified and pure membranes were investigated by carrying out X-ray diffraction (XRD and attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR. Scanning electron microscope (SEM and atomic force microscopy (AFM analyses were employed to examine the surface morphology and the bacteria anti-adhesion property of the membranes. The morphology measurements confirmed that even though after silver grafting the surface became more hydrophobic, the homogeneity increased and the flux reduction decreased after coating. Moreover a comparison between PVDF and PES revealed that CFU (colony forming units reduced 64.5% on PVDF surface and 31.1% on PES surface after modification. In conclusion, PVD improved the performance of the membrane antibiofouling, and it is more promising to be used for PVDF rather than PES.

  11. Structural, vibrational, electronic investigations and quantum chemical studies of 2-amino-4-methoxybenzothiazole.

    Science.gov (United States)

    Arjunan, V; Raj, Arushma; Santhanam, R; Marchewka, M K; Mohan, S

    2013-02-01

    Extensive vibrational investigations of 2-amino-4-methoxybenzothiazole have been carried out with FTIR and FT-Raman spectral techniques. The electronic structure of the molecule has been analysed by UV-Visible and NMR spectroscopies. The DFT studies were carried out with B3LYP and HF methods utilising 6-31G(d,p), 6-311++G(d,p) and cc-pVDZ basis sets to determine the structural, thermodynamical, vibrational, electronic characteristics of the compound and also to understand the electronic and steric influence of the methoxy amino groups on the skeletal frequencies. The mixing of the fundamental modes was determined with the help of total energy distribution (TED). The energies of the frontier molecular orbitals have also been determined. The kinetic and thermodynamic stability and chemical hardness of the molecule have been determined. Complete NBO analysis was also carried out to find out the intramolecular electronic interactions and their stabilisation energy. (1)H and (13)C NMR chemical shifts and the electronic transitions of the molecule are also discussed. Copyright © 2012 Elsevier B.V. All rights reserved.

  12. Use of a total traffic count metric to investigate the impact of roadways on asthma severity: A case-control study

    NARCIS (Netherlands)

    A.G. Cook (Angus); A.J.B.M. Devos (Annemarie); G. Pereira; L. Jardine (Laura); P. Weinstein (Philip)

    2011-01-01

    textabstractBackground: This study had two principal objectives: (i) to investigate the relationship between asthma severity and proximity to major roadways in Perth, Western Australia; (ii) to demonstrate a more accurate method of exposure assessment for traffic pollutants using an innovative

  13. 43 CFR 404.36 - Will Reclamation reimburse me for the cost of an appraisal investigation or a feasibility study...

    Science.gov (United States)

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Will Reclamation reimburse me for the cost... Reclamation reimburse me for the cost of an appraisal investigation or a feasibility study that was not...) or (b). Reclamation will not reimburse you or provide program funding for any expenses related to an...

  14. Basic investigation and analysis for preferred host rocks and natural analogue study area with reference to high level radioactive waste disposal

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Jeong Ryul; Park, J. K.; Hwang, D. H.; Lee, J. H.; Yun, H. S.; Kim, D. Y.; Park, H. S.; Koo, S. B.; Cho, J. D.; Kim, K. E. [Korea Inst. of Geology, Mining and Materials, Taejon (Korea, Republic of)

    1997-12-01

    The purpose of this study is basic investigation and analysis for preferred host rocks and natural analogue study area to develope underground disposal technique of high level radioactive waste in future. The study has been done for the crystalline rocks(especially granitic rocks) with emphasis of abandoned metallic mines and uranium ore deposits, and for the geological structure study by using gravity and aeromagnetic data. 138 refs., 54 tabs., 130 figs. (author)

  15. Investigation of the association between quality of life and depressive symptoms during postpartum period: a correlational study

    OpenAIRE

    Papamarkou, Maria; Sarafis, Pavlos; Kaite, Charis P.; Malliarou, Maria; Tsounis, Andreas; Niakas, Dimitris

    2017-01-01

    Background The onset of a major depressive episode is experienced by a large number of women in the weeks or months following delivery. Postpartum depression may deem those women experiencing it incapable of taking care for themselves, their family and their infants, while at the same time it could negatively affect their quality of life. The present study assessed the quality of life of a sample of mothers in Greece, in order to investigate the association between postpartum depression and q...

  16. Tularemia Outbreak Investigation in Kosovo: Case Control and Environmental Studies

    Science.gov (United States)

    Dedushaj, Isuf; Gjini, Ardiana; Jorgensen, Tine Rikke; Cotter, Benvon; Lieftucht, Alfons; D’Ancona, Fortunato; Dennis, David T.; Kosoy, Michael A.; Mulliqi-Osmani, Gjyle; Grunow, Roland; Kalaveshi, Ariana; Gashi, Luljeta; Humolli, Isme

    2002-01-01

    A large outbreak of tularemia occurred in Kosovo in the early postwar period, 1999-2000. Epidemiologic and environmental investigations were conducted to identify sources of infection, modes of transmission, and household risk factors. Case and control status was verified by enzyme-linked immunosorbent assay, Western blot, and microagglutination assay. A total of 327 serologically confirmed cases of tularemia pharyngitis and cervical lymphadenitis were identified in 21 of 29 Kosovo municipalities. Matched analysis of 46 case households and 76 control households suggested that infection was transmitted through contaminated food or water and that the source of infection was rodents. Environmental circumstances in war-torn Kosovo led to epizootic rodent tularemia and its spread to resettled rural populations living under circumstances of substandard housing, hygiene, and sanitation. PMID:11749751

  17. Sequences for Student Investigation

    Science.gov (United States)

    Barton, Jeffrey; Feil, David; Lartigue, David; Mullins, Bernadette

    2004-01-01

    We describe two classes of sequences that give rise to accessible problems for undergraduate research. These problems may be understood with virtually no prerequisites and are well suited for computer-aided investigation. The first sequence is a variation of one introduced by Stephen Wolfram in connection with his study of cellular automata. The…

  18. 100 Areas CERCLA ecological investigations

    Energy Technology Data Exchange (ETDEWEB)

    Landeen, D.S.; Sackschewsky, M.R.; Weiss, S.

    1993-09-01

    This document reports the results of the field terrestrial ecological investigations conducted by Westinghouse Hanford Company during fiscal years 1991 and 1992 at operable units 100-FR-3, 100-HR-3, 100-NR-2, 100-KR-4, and 100-BC-5. The tasks reported here are part of the Remedial Investigations conducted in support of the Comprehensive Environmental Response, compensation, and Liability Act of 1980 studies for the 100 Areas. These ecological investigations provide (1) a description of the flora and fauna associated with the 100 Areas operable units, emphasizing potential pathways for contaminants and species that have been given special status under existing state and/or federal laws, and (2) an evaluation of existing concentrations of heavy metals and radionuclides in biota associated with the 100 Areas operable units.

  19. 100 Areas CERCLA ecological investigations

    International Nuclear Information System (INIS)

    Landeen, D.S.; Sackschewsky, M.R.; Weiss, S.

    1993-09-01

    This document reports the results of the field terrestrial ecological investigations conducted by Westinghouse Hanford Company during fiscal years 1991 and 1992 at operable units 100-FR-3, 100-HR-3, 100-NR-2, 100-KR-4, and 100-BC-5. The tasks reported here are part of the Remedial Investigations conducted in support of the Comprehensive Environmental Response, compensation, and Liability Act of 1980 studies for the 100 Areas. These ecological investigations provide (1) a description of the flora and fauna associated with the 100 Areas operable units, emphasizing potential pathways for contaminants and species that have been given special status under existing state and/or federal laws, and (2) an evaluation of existing concentrations of heavy metals and radionuclides in biota associated with the 100 Areas operable units

  20. Execution programme for the initial site investigations at Forsmark

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-05-01

    In the feasibility studies that were completed in 2001, eight sites were identified as potentially suitable for hosting a repository. All the identified sites meet the safety requirements with respect to bedrock conditions that could be checked at that time. The feasibility studies have revealed good potential when it comes to the technical and environmental aspects as well. Based on an integrated evaluation SKB proposed to start site investigations with test drillings at three sites; Forsmark, Simpevarp and Tierp. Site investigations have started at Forsmark and Simpevarp. The municipal council of Tierp voted no to a site investigation in April 2002. The site investigations are divided into two main phases; initial and complete investigations. Initial site investigations are performed to identify the site within a specified area that is deemed to be most suitable for a deep repository and to determine whether the feasibility study's judgement of the suitability of the area holds up in the light of borehole data from repository depth. The initial site investigations are expected to take 1.5-2 years. If the assessment shows that the site has good potential to host a repository, complete site investigations will follow for an expected duration of 3.5-4 years. The purpose of the complete site investigations is to gather all information required to select one of the sites as the main alternative and to apply for a permit for construction of the deep repository at that site. A general programme in which the results from feasibility studies are summarized, the candidate sites presented and the framework of programme for the site investigation phase presented has been published. The general programme, and main references to the programme, specifies which data are required in order to design the repository and carry out a safety assessment, how the investigations should be carried out in order to provide these data, criteria with which the site must comply, as well as

  1. Execution programme for the initial site investigations at Forsmark

    International Nuclear Information System (INIS)

    2002-05-01

    In the feasibility studies that were completed in 2001, eight sites were identified as potentially suitable for hosting a repository. All the identified sites meet the safety requirements with respect to bedrock conditions that could be checked at that time. The feasibility studies have revealed good potential when it comes to the technical and environmental aspects as well. Based on an integrated evaluation SKB proposed to start site investigations with test drillings at three sites; Forsmark, Simpevarp and Tierp. Site investigations have started at Forsmark and Simpevarp. The municipal council of Tierp voted no to a site investigation in April 2002. The site investigations are divided into two main phases; initial and complete investigations. Initial site investigations are performed to identify the site within a specified area that is deemed to be most suitable for a deep repository and to determine whether the feasibility study's judgement of the suitability of the area holds up in the light of borehole data from repository depth. The initial site investigations are expected to take 1.5-2 years. If the assessment shows that the site has good potential to host a repository, complete site investigations will follow for an expected duration of 3.5-4 years. The purpose of the complete site investigations is to gather all information required to select one of the sites as the main alternative and to apply for a permit for construction of the deep repository at that site. A general programme in which the results from feasibility studies are summarized, the candidate sites presented and the framework of programme for the site investigation phase presented has been published. The general programme, and main references to the programme, specifies which data are required in order to design the repository and carry out a safety assessment, how the investigations should be carried out in order to provide these data, criteria with which the site must comply, as well as

  2. Investigating textbooks as crucial interfaces between culture, policy and teacher curricular practice : two contrasted case studies in France and Norway

    NARCIS (Netherlands)

    Pepin, B.; Gueudet, G.; Trouche, L.

    2013-01-01

    This paper reports on an investigation of mathematics curriculum documents, commonly used textbooks and teacher ‘curricular practice’ with respect to educational traditions in France and Norway. The study has helped to develop a deeper understanding of (1) educational traditions in France and

  3. OCT investigation of dental lesions

    Science.gov (United States)

    Osiac, Eugen; Popescu, Sanda Mihaela; Scrieciu, Monica; Mercuţ, Rǎzvan; Mercuţ, Veronica; Vǎtu, Mihaela

    2018-03-01

    There are several important non carious lesions affecting the tooth structure, lesions which may be classified into four clinical forms of dental wear: abfraction, erosion, attrition and abrasion, and different types of root resorption. Search for new, non-invasive and fast methods able to detect and describe such injuries is of utmost importance. Optical coherence tomography (OCT) proved itself as an appropriate investigation method for several medical fields including ophthalmology, dermatology, cardiology etc. Our study reveals OCT preliminary investigations as a promising tool for detecting and evaluating of the mentioned lesions.

  4. Comparative study on deformation and mechanical behavior of corroded pipe: Part I–Numerical simulation and experimental investigation under impact load

    Directory of Open Access Journals (Sweden)

    Dong-Man Ryu

    2017-09-01

    Full Text Available Experiments and a numerical simulation were conducted to investigate the deformation and impact behavior of a corroded pipe, as corrosion, fatigue, and collision phenomena frequently occur in subsea pipelines. This study focuses on the deformation of the corrosion region and the variation of the geometry of the pipe under impact loading. The experiments for the impact behavior of the corroded pipe were performed using an impact test apparatus to validate the results of the simulation. In addition, during the simulation, material tests were performed, and the results were applied to the simulation. The ABAQUS explicit finite element analysis program was used to perform numerical simulations for the parametric study, as well as experiment scenarios, to investigate the effects of defects under impact loading. In addition, the modified ASME B31.8 code formula was proposed to define the damage range for the dented pipe.

  5. Status report of shielding investigation in Japan

    International Nuclear Information System (INIS)

    Shindo, M.

    1964-01-01

    The Japan Atomic Energy Research Institute (JAERI) was established in 1954, and immediately proceeded with the construction of a research reactor. The first symposium in Japan on nuclear energy was held in 1957. Most of the papers presented in the field of reactor shielding were limited to shielding materials and their fabrication. In the first stage of our investigations, our efforts were devoted to practical design studies of reactor shielding. As a result of these studies, it was found that the formulae at hand for calculations were inadequate, but at that time no electronic computer was available in Japan nor were theoretical calculations very actively undertaken. Problems on nuclear ship shielding had been investigated at the Ship Research Institute, since 1956 and many fruitful results had been obtained. About that time the Japan Atomic Industry Forum started activities and took the initiative in organizing shielding research. Research workers in the shipbuilding industry in particular have been seriously studying shielding problems. Few years after the first symposium, problems concerning more fundamental studies were treated by many research workers. Shielding experiments using radioisotopes were carried out and many fruitful results were obtained. They are described in the this paper. Medium size electronic computers became available in Japan, permitting a theoretical study group to make an active contribution. They produced some codes, and their results are also described in the following sections. This constituted the second stage of our investigations. A swimming-pool reactor, JRR-4 (Japan Research Reactor-4), has been under construction at JAERI since 1962 and will become critical in autumn 1964. After characteristic tests it will be a very powerful tool for the shielding investigations. This id the beginning of the third stage of investigations

  6. Investigating the effects of ICT on innovation and performance of European hospitals: an exploratory study.

    Science.gov (United States)

    Arvanitis, Spyros; Loukis, Euripidis N

    2016-05-01

    Hospitals are making big investments in various types of ICT, so it is important to investigate their effects on innovation and performance. This paper presents an empirical study in this direction, based on data for 743 hospitals from 18 European countries. We specified and estimated econometrically five equations: one for product innovation, one for process innovation and three equations for the three different dimensions of (ICT-enabled) hospital performance. All five equations included various ICT-related variables reflecting ICT infrastructure and a series of important ICT applications, some of them hospital-specific, and some others of general business use, and also ICT personnel (viewed as a kind of 'soft' ICT investment), while the performance equations also included the two innovation measures.

  7. Investigation of Bias in Job Evaluation Ratings of Comparable Worth Study Participants.

    Science.gov (United States)

    Mount, Michael K.; Ellis, Rebecca A.

    1987-01-01

    Investigated the effects of knowledge of current pay levels and perceived job gender on subsequent job evaluations. Confirmed the hypothesis that jobs with high pay levels would receive higher evaluations than jobs with low pay levels. Found evidence of a pro-female bias in the job evaluation ratings of 53 job evaluators. (Author/ABB)

  8. A study to investigate the effectiveness of successful intelligence training program to increase academic hope

    Directory of Open Access Journals (Sweden)

    Mahbobeh Samavatian

    2014-02-01

    Full Text Available The purpose of this study is to investigate the effectiveness of successful intelligence training program on academic hopefulness of probation students of Esfahan University of Technology. The research is semi-experimental of pre-test, post-test type with control group. Research population includes all probation students of Esfahan University of Technology. The study chooses 30 female and male students and assigns them randomly into two groups of experimental and control. Experimental group participate in 13 successful intelligence-training sessions for 13 weeks. Research tools consists of, Hope in certain aspects. Statistical analysis is conducted using SPSS18 on inferential statistics level proportionate to data analysis level. Statistical test hypothesis are analyzed through univariate covariance and multivariate covariance analysis. The results show that successful intelligence program training was effective to enhance hopefulness of probation students (p < 0.05. Given the results of present research, successful intelligence program training can be used as an intervention method in order to decrease harms because of dormitory and student life.

  9. Environmental, Safety, and Health Plan for the remedial investigation/feasibility study at Oak Ridge National Laboratory, Oak Ridge, Tennessee

    International Nuclear Information System (INIS)

    1993-05-01

    This Environmental, Safety, and Health (ES ampersand H) Plan presents the concepts and methodologies to be followed during the remedial investigation/feasibility study (RI/FS) for Oak Ridge National Laboratory (ORNL) to protect the health and safety of employees, the public, and the environment. This ES ampersand H Plan acts as a management extension for ORNL and Martin Marietta Energy Systems, Inc. (Energy Systems) to direct and control implementation of the project ES ampersand H program. The subsections that follow describe the program philosophy, requirements, quality assurance measures, and methods for applying the ES ampersand H program to individual waste area grouping (WAG) remedial investigations. Hazardous work permits (HWPs) will be used to provide task-specific health and safety requirements

  10. An Investigation of Justice in Supply Chain Trust and Relationship Commitment - An Empirical Study of Pakistan

    Directory of Open Access Journals (Sweden)

    Ziaullah Muhammad

    2015-03-01

    Full Text Available In recent years supply chain integration (SCI has received increasing attention from scholars and practitioners. However, our knowledge of what influences the supply chain integration practice of relationship commitment is still very limited. The objective of this study is to investigate the relationship among supply chain justices (procedural, distributive and interactional, trust and inter-firms relationship commitment in mainland Pakistan. The research variables have considerable importance in the literature of supply chain management (SCM. The conceptual model comprises five hypotheses. Then hypotheses are tested via an empirical study in which data are collected from 170 manufacturers, distributors, suppliers and retailers of main stream spectrum industries in Pakistan. We used exploratory factor analysis (EFA, confirmatory factor analysis (CFA to examine the validity and reliability of the measurement model, and structural equation modeling (SEM to test the hypotheses. The findings delineate that supply chain justices can develop relationship commitment (affective and continuance via establishing trust among supply chain partners. Moreover, this study reveals interesting and useful implications of supply chain justices, trust and relationship commitment for practitioners.

  11. Dry-run of site investigation planning using the manual for preliminary investigation in Japan

    International Nuclear Information System (INIS)

    Akamura, Shigeki; Miwa, Tadashi; Tanaka, Tatsuya; Shiratsuchi, Hiroshi; Horio, Atsushi

    2011-01-01

    A stepwise site selection process has been adopted for geological disposal of HLW in Japan. Literature surveys, followed by preliminary investigations (PI) and, finally, detailed investigations in underground facilities will be carried out in the successive selection stages. In the PI stage, surface-based investigations such as borehole surveys and geophysical prospecting will be implemented. In order to conduct the PI appropriately and efficiently within a restricted timeframe and budget, planning and management of PI are very important. NUMO therefore compiled existing knowledge and experience in the planning and managing of investigations in the form of manuals to be used to improve and maintain internal expertise. The first editions of the two manuals were prepared on the basis of experience overseas, and then they were revised by taking technological environment, laws and regulation in Japan into consideration. This paper introduces the procedure of PI planning using manual as well as the results of the dry-run, with the Yokosuka area as a hypothetical PI area, where the monstraction study is under way. Based on the dry-run, applicability of the manual is checked and, at the same time, further revisions are made to improve the content. (author)

  12. The academic librarian as co-investigator on an interprofessional primary research team: a case study.

    Science.gov (United States)

    Janke, Robert; Rush, Kathy L

    2014-06-01

    The objective of this study was to explore the role librarians play on research teams. The experiences of a librarian and a faculty member are situated within the wider literature addressing collaborations between health science librarians and research faculty. A case study approach is used to outline the involvement of a librarian on a team created to investigate the best practices for integrating nurses into the workplace during their first year of practice. Librarians contribute to research teams including expertise in the entire process of knowledge development and dissemination including the ability to navigate issues related to copyright and open access policies of funding agencies. The librarian reviews the various tasks performed as part of the research team ranging from the grant application, to working on the initial literature review as well as the subsequent manuscripts that emerged from the primary research. The motivations for joining the research team, including authorship and relationship building, are also discussed. Recommendations are also made in terms of how librarians could increase their participation on research teams. The study shows that librarians can play a key role on interprofessional primary research teams. © 2014 The authors. Health Information and Libraries Journal © 2014 Health Libraries Group.

  13. Seniors Falls Investigative Methodology (SFIM): A Systems Approach to the Study of Falls in Seniors

    Science.gov (United States)

    Zecevic, Aleksandra A.; Salmoni, Alan W.; Lewko, John H.; Vandervoort, Anthony A.

    2007-01-01

    An in-depth understanding of human factors and human error is lacking in current research on seniors' falls. Additional knowledge is needed to understand why seniors are falling. The purpose of this article is to describe the adapting of the Integrated Safety Investigation Methodology (ISIM) (used for investigating transportation and industrial…

  14. SRP baseline hydrogeologic investigation: Aquifer characterization

    Energy Technology Data Exchange (ETDEWEB)

    Strom, R.N.; Kaback, D.S.

    1992-03-31

    An investigation of the mineralogy and chemistry of the principal hydrogeologic units and the geochemistry of the water in the principal aquifers at Savannah River Site (SRS) was undertaken as part of the Baseline Hydrogeologic Investigation. This investigation was conducted to provide background data for future site studies and reports and to provide a site-wide interpretation of the geology and geochemistry of the Coastal Plain Hydrostratigraphic province. Ground water samples were analyzed for major cations and anions, minor and trace elements, gross alpha and beta, tritium, stable isotopes of hydrogen, oxygen, and carbon, and carbon-14. Sediments from the well borings were analyzed for mineralogy and major and minor elements.

  15. An investigation on technical feasibilities of fuel cycle for high temperature gas-cooled reactor (Case study)

    International Nuclear Information System (INIS)

    Sumita, Junya; Ueta, Shohei; Aihara, Jun; Shibata, Taiju; Sawa, Kazuhiro

    2008-03-01

    In accordance with the basic policy of effectively using nuclear fuel resources, the FBR cycle, one of the most possible fuel cycle in the future, will be adapted after plu-thermal program by LWR in Japanese nuclear cycle plan. In this paper, a case study of technical investigation of HTGR fuel cycle based on HTGR fuel cycle proposed to adapt to Japanese nuclear fuel cycle plan were carried out from the viewpoint of effective utilization of uranium, fabrication technologies of MOX fuel, reprocessing technologies, amount of interim storage of HTGR fuel and graphite waste. As a result, the fuel cycle for HTGR is expected to be possible technically. (author)

  16. A Qualitative Study Investigating Gender Differences in Primary Work Stressors and Levels of Job Satisfaction in Greek Junior Hospital Doctors

    Science.gov (United States)

    Antoniou, Alexander-Stamatios; Cooper, Cary L.; Davidson, Marilyn J.

    2008-01-01

    Primary work stressors and job satisfaction/dissatisfaction in Greek Junior Hospital Doctors (JHDs) are investigated to identify similarities and differences in the reports obtained from male and female hospital doctors. Participants in the study included 32 male and 28 female Greek hospital doctors who provided information through…

  17. Oskarshamn site investigation. Programme for further investigations of bedrock, soil, water and environment in Laxemar subarea

    International Nuclear Information System (INIS)

    2006-03-01

    SKB (the Swedish Nuclear Fuel and Waste Management Co), has been conducting a site investigation at Simpevarp and Laxemar in Oskarshamn for siting of a final repository for spent nuclear fuel. An equivalent investigation is being conducted in Forsmark in Ohmmeter's. The initial part of the site investigations had been completed for the both of the subareas Simpevarp and Laxemar in the autumn of 2004. Based on the results of these investigations, SKB preliminarily prioritized the Laxemar subarea for further investigations. A programme was presented for the first stage of the complete site investigation in the Laxemar subarea, along with the main features of the remainder of the site investigation. The programme included investigations up until the summer of 2005 and was particularly aimed at obtaining answers to several vital questions so that the subsequent investigations could be focused on the rock areas judged to be most suitable for a final repository. These investigations have now been completed. This report presents the programme for the remainder of the site investigation. The points of departure are the general goals for the Deep Repository Project during the site investigation phase, analyses and evaluations of data from completed investigations, and the needs for additional data to be able to evaluate the site as a siting alternative for the final repository. The account mainly covers the investigations on the site. All other work - analyses, site descriptive modelling, facility design, safety assessments and studies and assessments of consequences for the environment, human health and society - are only mentioned to the extent necessary in order to place the investigations in their context. The direction of the site investigation in Oskarshamn and the investigation programme presented in this report is based on SKB's preliminary decision to prioritize the Laxemar subarea for further investigations. A final decision on the direction of the site

  18. Factors influencing when intensive care unit nurses go to the bedside to investigate patient related alarms: A descriptive qualitative study.

    Science.gov (United States)

    Despins, Laurel A

    2017-12-01

    This study examines what prompts the intensive care unit (ICU) nurse to go to the patient's bedside to investigate an alarm and the influences on the nurse's determination regarding how quickly this needs to occur. A qualitative descriptive design guided data collection and analysis. Individual semi-structured interviews were conducted. Thematic analysis guided by the Patient Risk Detection Theoretical Framework was applied to the data. Four specialty intensive care units in an academic medical center. ICU nurses go the patient's bedside in response to an alarm to catch patient deterioration and avert harm. Their determination of the immediacy of patient risk and their desire to prioritize their bedside investigations to true alarms influences how quickly they proceed to the bedside. Ready visual access to physiological data and waveform configurations, experience, teamwork, and false alarms are important determinants in the timing of ICU nurses' bedside alarm investigations. Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. Sampling strategies for indoor radon investigations

    International Nuclear Information System (INIS)

    Prichard, H.M.

    1983-01-01

    Recent investigations prompted by concern about the environmental effects of residential energy conservation have produced many accounts of indoor radon concentrations far above background levels. In many instances time-normalized annual exposures exceeded the 4 WLM per year standard currently used for uranium mining. Further investigations of indoor radon exposures are necessary to judge the extent of the problem and to estimate the practicality of health effects studies. A number of trends can be discerned as more indoor surveys are reported. It is becoming increasingly clear that local geological factors play a major, if not dominant role in determining the distribution of indoor radon concentrations in a given area. Within a giving locale, indoor radon concentrations tend to be log-normally distributed, and sample means differ markedly from one region to another. The appreciation of geological factors and the general log-normality of radon distributions will improve the accuracy of population dose estimates and facilitate the design of preliminary health effects studies. The relative merits of grab samples, short and long term integrated samples, and more complicated dose assessment strategies are discussed in the context of several types of epidemiological investigations. A new passive radon sampler with a 24 hour integration time is described and evaluated as a tool for pilot investigations

  20. Investigating temperature breaks in the summer fruit export cold chain: A case study

    Directory of Open Access Journals (Sweden)

    Heinri W. Freiboth

    2013-11-01

    Full Text Available There is concern in the South African fruit industry that a large amount of fruit and money is lost every season due to breaks in the fruit export cold chain. The possibility of a large percentage of losses in a significant sector of the economy warranted further investigation. This article attempted to highlight some of the possible problem areas in the cold chain, from the cold store to the port, by analysing historic temperature data from different fruit export supply chains of apples, pears and grapes. In addition, a trial shipment of apples was used to investigate temperature variation between different pallets in the same container. This research has added value to the South African fruit industry by identifying the need to improve operational procedures in the cold chain.

  1. Human intervention study to investigate the intestinal accessibility and bioavailability of anthocyanins from bilberries.

    Science.gov (United States)

    Mueller, Dolores; Jung, Kathrin; Winter, Manuel; Rogoll, Dorothee; Melcher, Ralph; Richling, Elke

    2017-09-15

    We investigated the importance of the large intestine on the bioavailability of anthocyanins from bilberries in humans with/without a colon. Low bioavailability of anthocyanins in plasma and urine was observed in the frame of this study. Anthocyanins reached the circulation mainly as glucuronides. Analysis of ileal effluents (at end of small intestine) demonstrated that 30% of ingested anthocyanins were stable during 8h passage through the upper intestine. Only 20% degradants were formed and mostly intact anthocyanins were absorbed from the small intestine. Higher amounts of degradants than anthocyanins reached the circulation after bilberry extract consumption in both groups of subjects. Comparison of the bioavailability of anthocyanins in healthy subjects versus ileostomists revealed substantially higher amounts of anthocyanins and degradants in the plasma/urine of subjects with an intact gut. The results suggested that the colon is a significant site for absorption of bioactive components such as anthocyanins and their degradation products. Copyright © 2017 Elsevier Ltd. All rights reserved.

  2. Investigation of the dielectric properties of shale

    International Nuclear Information System (INIS)

    Martemyanov, Sergey M.

    2011-01-01

    The article is dedicated to investigation of the dielectric properties of oil shale. Investigations for samples prepared from shale mined at the deposit in Jilin Province in China were done. The temperature and frequency dependences of rock characteristics needed to calculate the processes of their thermal processing are investigated. Frequency dependences for the relative dielectric constant and dissipation factor of rock in the frequency range from 0,1 Hz to 1 MHz are investigated. The temperature dependences for rock resistance, dielectric capacitance and dissipation factor in the temperature range from 20 to 600°C are studied. Key words: shale, dielectric properties, relative dielectric constant, dissipation factor, temperature dependence, frequency dependence

  3. Mechanistic Investigation of Molybdate-Catalysed Transfer Hydrodeoxygenation

    DEFF Research Database (Denmark)

    Larsen, Daniel Bo; Petersen, Allan Robertson; Dethlefsen, Johannes Rytter

    2016-01-01

    The molybdate-catalysed transfer hydrodeoxygenation (HDO) of benzyl alcohol to toluene driven by oxidation of the solvent isopropyl alcohol to acetone has been investigated by using a combination of experimental and computational methods. A Hammett study that compared the relative rates for the t......The molybdate-catalysed transfer hydrodeoxygenation (HDO) of benzyl alcohol to toluene driven by oxidation of the solvent isopropyl alcohol to acetone has been investigated by using a combination of experimental and computational methods. A Hammett study that compared the relative rates...

  4. Research Costs Investigated: A Study Into the Budgets of Dutch Publicly Funded Drug-Related Research.

    Science.gov (United States)

    van Asselt, Thea; Ramaekers, Bram; Corro Ramos, Isaac; Joore, Manuela; Al, Maiwenn; Lesman-Leegte, Ivonne; Postma, Maarten; Vemer, Pepijn; Feenstra, Talitha

    2018-01-01

    The costs of performing research are an important input in value of information (VOI) analyses but are difficult to assess. The aim of this study was to investigate the costs of research, serving two purposes: (1) estimating research costs for use in VOI analyses; and (2) developing a costing tool to support reviewers of grant proposals in assessing whether the proposed budget is realistic. For granted study proposals from the Netherlands Organization for Health Research and Development (ZonMw), type of study, potential cost drivers, proposed budget, and general characteristics were extracted. Regression analysis was conducted in an attempt to generate a 'predicted budget' for certain combinations of cost drivers, for implementation in the costing tool. Of 133 drug-related research grant proposals, 74 were included for complete data extraction. Because an association between cost drivers and budgets was not confirmed, we could not generate a predicted budget based on regression analysis, but only historic reference budgets given certain study characteristics. The costing tool was designed accordingly, i.e. with given selection criteria the tool returns the range of budgets in comparable studies. This range can be used in VOI analysis to estimate whether the expected net benefit of sampling will be positive to decide upon the net value of future research. The absence of association between study characteristics and budgets may indicate inconsistencies in the budgeting or granting process. Nonetheless, the tool generates useful information on historical budgets, and the option to formally relate VOI to budgets. To our knowledge, this is the first attempt at creating such a tool, which can be complemented with new studies being granted, enlarging the underlying database and keeping estimates up to date.

  5. Investigating the large degeneracy Kondo lattice metamagnet CeTiGe: Crystal growth and doping studies

    Energy Technology Data Exchange (ETDEWEB)

    Gruner, T.; Caroca-Canales, N.; Deppe, M.; Geibel, C. [MPI fuer Chemische Physik fester Stoffe, 01187, Dresden (Germany); Sereni, J. [Centro Atomico Bariloche, 8400, S. C. de Bariloche (Argentina)

    2011-07-01

    CeTiGe is a paramagnetic Kondo lattice system with a large orbital degeneracy involved in the formation of the heavy Fermion ground state. Recently we discovered that this compound presents a huge metamagnetic transition at B{sub MMT} {approx} 13 T, with much larger anomalies in magnetization, magnetoresistance and magnetostriction than in the archetypical Kondo lattice metamagnet CeRu{sub 2}Si{sub 2}. Since CeTiGe forms in a pronounced peritectic reaction the growth of single crystals is difficult. We therefore studied the Ce-Ti-Ge ternary metallographic phase diagram to get a sound basis for future crystal growth attempts. Preliminary results of growth experiments based on these studies are promising and shall be discussed. Furthermore, Ti-rich CeTiGe was recently reported to present a high temperature phase crystallizing in the closely related CeScSi structure type. In order to study this structural instability and the effect on the physical properties, we studied the effect of substituting Sc for Ti, since pure CeScGe crystallizes in the CeScSi structure type. In well annealed samples we observed a two phase region in the range 10% - 25%-Sc-substitution. Preliminary investigations of the CeSc{sub x}Ti{sub 1-x}Ge alloy suggest it is a promising candidate for the observation of a ferromagnetic quantum critical point in a large degeneracy Kondo lattice system.

  6. The Koori Growing Old Well Study: investigating aging and dementia in urban Aboriginal Australians.

    Science.gov (United States)

    Radford, Kylie; Mack, Holly A; Robertson, Hamish; Draper, Brian; Chalkley, Simon; Daylight, Gail; Cumming, Robert; Bennett, Hayley; Jackson Pulver, Lisa; Broe, Gerald A

    2014-06-01

    Dementia is an emerging health priority in Australian Aboriginal communities, but substantial gaps remain in our understanding of this issue, particularly for the large urban section of the population. In remote Aboriginal communities, high prevalence rates of dementia at relatively young ages have been reported. The current study is investigating aging, cognitive decline, and dementia in older urban/regional Aboriginal Australians. We partnered with five Aboriginal communities across the eastern Australian state of New South Wales, to undertake a census of all Aboriginal men and women aged 60 years and over residing in these communities. This was followed by a survey of the health, well-being, and life history of all consenting participants. Participants were also screened using three cognitive instruments. Those scoring below designated cut-offs, and a 20% random sample of those scoring above (i.e. "normal" range), completed a contact person interview (with a nominated family member) and medical assessment (blind to initial screening results), which formed the basis of "gold standard" clinical consensus determinations of cognitive impairment and dementia. This paper details our protocol for a population-based study in collaboration with local Aboriginal community organizations. The study will provide the first available prevalence rates for dementia and cognitive impairment in a representative sample of urban Aboriginal people, across city and rural communities, where the majority of Aboriginal Australians live. It will also contribute to improved assessment of dementia and cognitive impairment and to the understanding of social determinants of successful aging, of international significance.

  7. Investigation of Thermophysical Parameters Properties for Enhancing Overpressure Mechanism Estimation. Case Study: Miri Area, West Baram Delta

    Science.gov (United States)

    Adha, Kurniawan; Yusoff, Wan Ismail Wan; Almanna Lubis, Luluan

    2017-10-01

    Determining the pore pressure data and overpressure zone is a compulsory part of oil and gas exploration in which the data can enhance the safety with profit and preventing the drilling hazards. Investigation of thermophysical parameters such as temperature and thermal conductivity can enhance the pore pressure estimation for overpressure mechanism determination. Since those parameters are dependent on rock properties, it may reflect the changes on the column of thermophysical parameters when there is abnormally in pore pressure. The study was conducted in “MRI 1” well offshore Sarawak, where a new approach method designed to determine the overpressure generation. The study was insisted the contribution of thermophysical parameters for supporting the velocity analysis method, petrophysical analysis were done in these studies. Four thermal facies were identified along the well. The overpressure developed below the thermal facies 4, where the pressure reached 38 Mpa and temperature was increasing significantly. The velocity and the thermal conductivity cross plots shows a linear relationship since the both parameters mainly are the function of the rock compaction. When the rock more compact, the particles were brought closer into contact and making the sound wave going faster while the thermal conductivity were increasing. In addition, the increment of temperature and high heat flow indicated the presence of fluid expansion mechanism. Since the shale sonic velocity and density analysis were the common methods in overpressure mechanism and pore pressure estimation. As the addition parameters for determining overpressure zone, the presence of thermophysical analysis was enhancing the current method, where the current method was the single function of velocity analysis. The presence of thermophysical analysis will improve the understanding in overpressure mechanism determination as the new input parameters. Thus, integrated of thermophysical technique and velocity

  8. On a computational study for investigating acoustic streaming and heating during focused ultrasound ablation of liver tumor

    International Nuclear Information System (INIS)

    Solovchuk, Maxim A.; Sheu, Tony W.H.; Thiriet, Marc; Lin, Win-Li

    2013-01-01

    The influences of blood vessels and focused location on temperature distribution during high-intensity focused ultrasound (HIFU) ablation of liver tumors are studied numerically. A three-dimensional acoustics-thermal-fluid coupling model is employed to compute the temperature field in the hepatic cancerous region. The model construction is based on the linear Westervelt and bioheat equations as well as the nonlinear Navier–Stokes equations for the liver parenchyma and blood vessels. The effect of acoustic streaming is also taken into account in the present HIFU simulation study. Different blood vessel diameters and focal point locations were investigated. We found from this three-dimensional numerical study that in large blood vessels both the convective cooling and acoustic streaming can considerably change the temperature field and the thermal lesion near blood vessels. If the blood vessel is located within the beam width, both acoustic streaming and blood flow cooling effects should be addressed. The temperature rise on the blood vessel wall generated by a 1.0 MHz focused ultrasound transducer with the focal intensity 327 W/cm 2 was 54% lower when acoustic streaming effect was taken into account. Subject to the applied acoustic power the streaming velocity in a 3 mm blood vessel is 12 cm/s. Thirty percent of the necrosed volume can be reduced, when taking into account the acoustic streaming effect. -- Highlights: • 3D three-field coupling physical model for focused ultrasound tumor ablation is presented. • Acoustic streaming and blood flow cooling effects on ultrasound heating are investigated. • Acoustic streaming can considerably affect the temperature distribution. • The lesion can be reduced by 30% due to the acoustic streaming effect. • Temperature on the blood vessel wall is reduced by 54% due to the acoustic streaming effect

  9. Site investigations for final disposal of high-level nuclear waste

    International Nuclear Information System (INIS)

    Aeikaes, T.; Laine, T.

    1982-12-01

    Research concerning disposal of high-level nuclear waste of the Industrial Power Company Ltd has focused on deep underground disposal in Finnish precambrian bedrock. The present target is to have a repository for high-level waste in operation by 2020. Selection of the repository site is based on site investigations. In addition to geosciences, selection of appropriate site includes many branches of studies; engineering, safety analysis, ecology, transport, demography etc. The investigations required for site selection for high-level waste have been arranged in a sequence of four phases. The aim of the phases is that investigations become more and more detailed as the selection process continues. Phase I of the investigations is the characterization of potential areas. This comprises establishment of criteria for site selection and identification of areas that meet selection criteria. Objective of these studies is to determine areas for phase II field investigations. The studies are largely made by reviewing existing data and remote-sensing techniques. Phase II field investigations will be undertaken between 1986-1992. The number of potential candidates for repository site is reduced to few preferred areas by preceeding generic study. The site selection process culminates in phase III in site confirmation studies carried out at 2...3 most suitable sites during 1992-2010. This is then followed by phase IV, which comprises very detailed investigations at the selected site. An alternative for these investigations is to undertake them by using pilot shaft and drifts. Active development is taking place in all phases concerning investigation methods, criteria, parameters, data processing and modelling. The applicability of the various investigation methods and techniques is tested in a deep borehole in phase I. The co-operation with countries with similar geological conditions makes it possible to compare results obtained by different techniques

  10. Evaluating advancements in accident investigations using a novel framework

    NARCIS (Netherlands)

    Karanikas, N.; Soltani, P.; de Boer, R.J.; Roelen, A.

    2015-01-01

    Safety is monitored by various proactive and reactive methods, including the investigation of adverse accidents and incidents, which are collectively known as safety investigations. In this study we demonstrate how accident and incident investigation reports can be useful to identify implicit safety

  11. Redundant systematic reviews on the same topic in surgery: a study protocol for a meta-epidemiological investigation.

    Science.gov (United States)

    Katsura, Morihiro; Kuriyama, Akira; Tada, Masafumi; Yamamoto, Kazumichi; Furukawa, Toshi A

    2017-08-21

    We are witnessing an explosive increase in redundant and overlapping publications of systematic reviews and meta-analyses (SRs/MAs) on the same topic, which often present conflicting results and interpretations, in the current medical literature. They represent wasted efforts on the part of investigators and peer reviewers and may confuse and possibly mislead clinicians and policymakers. Here, we present a protocol for a meta-epidemiological investigation to describe how often there are overlapping SRs/MAs on the same topic, to assess the quality of these multiple publications, and to investigate the causes of discrepant results between multiple SRs/MAs in the field of major surgery. We will use MEDLINE/PubMed to identify all SRs/MAs of randomised controlled trials (RCTs) published in 2015 regarding major surgical interventions. After identifying the 'benchmark' SRs/MAs published in 2015, a process of screening in MEDLINE will be carried out to identify the previous SRs/MAs of RCTs on the same topic that were published within 5 years of the 'benchmark' SRs/MAs. We will tabulate the number of previous SRs/MAs on the same topic of RCTs, and then describe their variations in numbers of RCTs included, sample sizes, effect size estimates and other characteristics. We will also assess the differences in quality of each SR/MA using A Measurement Tool to Assess Systematic Reviews (AMSTAR) score. Finally, we will investigate the potential reasons to explain the discrepant results between multiple SRs/MAs. No formal ethical approval and informed consent are required because this study will not collect primary individual data. The intended audiences of the findings include clinicians, healthcare researchers and policymakers. We will publish our findings as a scientific report in a peer-reviewed journal. In PROSPERO CRD42017059077, March 2017. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial

  12. Experimental Investigation of Magnetohydrodynamics Effects in Molten Metals and Study of Homogeneity of Radioactive Mercury Amalgams

    CERN Document Server

    Astone, A

    2002-01-01

    The high neutrino output demanded for a neutri no factory requests a high power proton beam interacting with a static target. The additional circumstances of limited space and long term stability ask for development of novel concepts for such types of targets. In our working group, part of the Neutri no Factory Working Group (NFWG) of CERN, we are investigating on the proton interaction with the mercury target. This is called the study of proton induced shocks in molten metal. In the US scheme for a neutrino factory the interaction between proton beam and the mercury jet target takes place inside a 20 Tesla solenoidal magnetic field, which serv es as a focusing device for the produced particles. This field of study is refe rred to as Magneto Hydrodynamics (MHD). The high power proton beam deposits a large amount of energy in the small volume of the target, which results in disruption. The aim is to establi...

  13. LET’s start new a LETS: Learning from a case-study investigation in Brno, Czech Republic

    Directory of Open Access Journals (Sweden)

    Lukáš Kala

    2013-12-01

    Full Text Available This paper brings information about the operation of RozLEŤSe, a LETS (Local Exchange Trading System network, based inBrno. LETS are parallel sustainable monetary systems, in which local community networks attempt to extricate themselves from the international economy by using their own currency. LETS is supposed to promote sustainable development by localising economic development. Although, there used to be several LETS group in the Czech Republic, all of them vanished during the first few years of the new millennium.  RozLEŤSe was built from the remains of former LETS groups. Hence, the aim of this study is to determine possible threats to the future existence of the group and evaluate its current operations. This research is a sociological case study investigation examining the socio-demographic characteristics, motivations and organisational functioning of the group. We point out some serious threats to the group (lack of supply, growth in negative credit, decrease in trust and offer possible solutions. 

  14. Oskarshamn site investigation. Programme for further investigations of bedrock, soil, water and environment in Laxemar subarea

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-03-15

    SKB (the Swedish Nuclear Fuel and Waste Management Co), has been conducting a site investigation at Simpevarp and Laxemar in Oskarshamn for siting of a final repository for spent nuclear fuel. An equivalent investigation is being conducted in Forsmark in Ohmmeter's. The initial part of the site investigations had been completed for the both of the subareas Simpevarp and Laxemar in the autumn of 2004. Based on the results of these investigations, SKB preliminarily prioritized the Laxemar subarea for further investigations. A programme was presented for the first stage of the complete site investigation in the Laxemar subarea, along with the main features of the remainder of the site investigation. The programme included investigations up until the summer of 2005 and was particularly aimed at obtaining answers to several vital questions so that the subsequent investigations could be focused on the rock areas judged to be most suitable for a final repository. These investigations have now been completed. This report presents the programme for the remainder of the site investigation. The points of departure are the general goals for the Deep Repository Project during the site investigation phase, analyses and evaluations of data from completed investigations, and the needs for additional data to be able to evaluate the site as a siting alternative for the final repository. The account mainly covers the investigations on the site. All other work - analyses, site descriptive modelling, facility design, safety assessments and studies and assessments of consequences for the environment, human health and society - are only mentioned to the extent necessary in order to place the investigations in their context. The direction of the site investigation in Oskarshamn and the investigation programme presented in this report is based on SKB's preliminary decision to prioritize the Laxemar subarea for further investigations. A final decision on the direction of the site

  15. Investigation of 95 variants identified in a genome-wide study for association with mortality after acute coronary syndrome

    Directory of Open Access Journals (Sweden)

    Winkelmann Bernhard R

    2011-09-01

    Full Text Available Abstract Background Genome-wide association studies (GWAS have identified new candidate genes for the occurrence of acute coronary syndrome (ACS, but possible effects of such genes on survival following ACS have yet to be investigated. Methods We examined 95 polymorphisms in 69 distinct gene regions identified in a GWAS for premature myocardial infarction for their association with post-ACS mortality among 811 whites recruited from university-affiliated hospitals in Kansas City, Missouri. We then sought replication of a positive genetic association in a large, racially diverse cohort of myocardial infarction patients (N = 2284 using Kaplan-Meier survival analyses and Cox regression to adjust for relevant covariates. Finally, we investigated the apparent association further in 6086 additional coronary artery disease patients. Results After Cox adjustment for other ACS risk factors, of 95 SNPs tested in 811 whites only the association with the rs6922269 in MTHFD1L was statistically significant, with a 2.6-fold mortality hazard (P = 0.007. The recessive A/A genotype was of borderline significance in an age- and race-adjusted analysis of the entire combined cohort (N = 3095; P = 0.052, but this finding was not confirmed in independent cohorts (N = 6086. Conclusions We found no support for the hypothesis that the GWAS-identified variants in this study substantially alter the probability of post-ACS survival. Large-scale, collaborative, genome-wide studies may be required in order to detect genetic variants that are robustly associated with survival in patients with coronary artery disease.

  16. Cosmic ray investigations

    International Nuclear Information System (INIS)

    Zatsepin, Georgii T; Roganova, Tat'yana M

    2009-01-01

    The history of cosmic ray research at the Lebedev Institute beginning with the first work and continuing up to now is reviewed. The milestones and main avenues of research are outlined. Pioneering studies on the nuclear cascade process in extensive air showers, investigations of the Vavilov-Cherenkov radiation, and some work on the origin of cosmic rays are discussed. Recent data on ultrahigh-energy particle detection at the Pierre Auger Observatory and the High Resolution Fly's Eye (HiRes) experiments are presented. (conferences and symposia)

  17. DNA testing in homicide investigations.

    Science.gov (United States)

    Prahlow, Joseph A; Cameron, Thomas; Arendt, Alexander; Cornelis, Kenneth; Bontrager, Anthony; Suth, Michael S; Black, Lisa; Tobey, Rebbecca; Pollock, Sharon; Stur, Shawn; Cotter, Kenneth; Gabrielse, Joel

    2017-10-01

    Objectives With the widespread use of DNA testing, police, death investigators, and attorneys need to be aware of the capabilities of this technology. This review provides an overview of scenarios where DNA evidence has played a major role in homicide investigations in order to highlight important educational issues for police, death investigators, forensic pathologists, and attorneys. Methods This was a nonrandom, observational, retrospective study. Data were obtained from the collective files of the authors from casework during a 15-year period, from 2000 through 2014. Results A series of nine scenarios, encompassing 11 deaths, is presented from the standpoint of the police and death investigation, the forensic pathology autopsy performance, the subsequent DNA testing of evidence, and, ultimately, the final adjudication of cases. Details of each case are presented, along with a discussion that focuses on important aspects of sample collection for potential DNA testing, especially at the crime scene and the autopsy. The presentation highlights the diversity of case and evidence types in which DNA testing played a valuable role in the successful prosecution of the case. Conclusions By highlighting homicides where DNA testing contributed to the successful adjudication of cases, police, death investigators, forensic pathologists, and attorneys will be better informed regarding the types of evidence and situations where such testing is of potential value.

  18. Investigating accidents involving aircraft manufactured from polymer composite materials

    Science.gov (United States)

    Dunn, Leigh

    This study looks into the examination of polymer composite wreckage from the perspective of the aircraft accident investigator. It develops an understanding of the process of wreckage examination as well as identifying the potential for visual and macroscopic interpretation of polymer composite aircraft wreckage. The in-field examination of aircraft wreckage, and subsequent interpretations of material failures, can be a significant part of an aircraft accident investigation. As the use of composite materials in aircraft construction increases, the understanding of how macroscopic failure characteristics of composite materials may aid the field investigator is becoming of increasing importance.. The first phase of this research project was to explore how investigation practitioners conduct wreckage examinations. Four accident investigation case studies were examined. The analysis of the case studies provided a framework of the wreckage examination process. Subsequently, a literature survey was conducted to establish the current level of knowledge on the visual and macroscopic interpretation of polymer composite failures. Relevant literature was identified and a compendium of visual and macroscopic characteristics was created. Two full-scale polymer composite wing structures were loaded statically, in an upward bending direction, until each wing structure fractured and separated. The wing structures were subsequently examined for the existence of failure characteristics. The examination revealed that whilst characteristics were present, the fragmentation of the structure destroyed valuable evidence. A hypothetical accident scenario utilising the fractured wing structures was developed, which UK government accident investigators subsequently investigated. This provided refinement to the investigative framework and suggested further guidance on the interpretation of polymer composite failures by accident investigators..

  19. Radioimmunoassay of somatostatin: methodological problems and physiological investigations

    International Nuclear Information System (INIS)

    Penman, E.; Wass, J.A.H.

    1981-01-01

    Somatostatin, a tetradecapeptide, has a wide distribution throughout the central nervous system and the gastrointestinal tract and a broad spectrum of biological actions. In order to investigate its various physiological roles in man, a radioimmunoassay was developed for somatostatin in human blood plasma, which is described here. This RIA was used to investigate possible factors influencing somatostatin secretion. Changes in somatin levels produced by changes in insulin, glucagon and growth hormone levels were studied via the response of plasma immunoreactive somatostatin to hormonal stimuli in normal man. The influence of fasting and food consumption was studied; and the site of origin of circulating immunoreactive somatostatin was investigated in patients. (Auth.)

  20. Investigating the micromorphological differences of the implant-abutment junction and their clinical implications: a pilot study.

    Science.gov (United States)

    Mattheos, Nikos; Li, Xiaona; Zampelis, Antonios; Ma, Li; Janda, Martin

    2016-11-01

    The aim of this pilot study was to investigate the morphological micro-features of three commercially available implant-abutment joints, using compatible and original prosthetic components. Furthermore, possible correlations between the micromorphology and potential functional complications were investigated with the use of finite element analysis. Three abutments (one original and two compatibles) were torqued on original Straumann RN implants, as according to each of the manufacturer's instructions. The implant-abutment units were sliced in the microtome and photographed under different magnifications (10×-500×) through a scanning electron microscope. Finite element analysis models were reconstructed for each of the implant-abutment units using the precise measurements from the SEM. Differences in stress, strain and deformation for the three different abutments were then calculated using ANSYS Workbench v13. Major dimensional differences were identified between all studied contact areas of the three units. The tight contact in the implant shoulder was similar in all three units, but engagement of the internal connection and, in particular, the anti-rotation elements was seriously compromised in the compatible abutments. One compatible abutment demonstrated compromised engagement of the abutment screw as well. Equivalent stress and strain in the FEA were much higher for the compatible abutments. An evaluation of the sequence of preload application revealed differences in the pattern of deformation between the original and compatible abutments, which can have serious clinical implications. Compatible abutments can present critical morphological differences from the original ones. The differences in the cross-sectional geometry result in large differences in the overall contact areas, both in terms of quality and quantity which could have serious implications for the long-term stability of the prosthesis. © 2015 John Wiley & Sons A/S. Published by John Wiley

  1. Causes of death among females-investigating beyond maternal causes: a community-based longitudinal study.

    Science.gov (United States)

    Melaku, Yohannes Adama; Weldearegawi, Berhe; Aregay, Alemseged; Tesfay, Fisaha Haile; Abreha, Loko; Abera, Semaw Ferede; Bezabih, Afework Mulugeta

    2014-09-10

    In developing countries, investigating mortality levels and causes of death among all age female population despite the childhood and maternal related deaths is important to design appropriate and tailored interventions and to improve survival of female residents. Under Kilite-Awlealo Health and Demographic Surveillance System, we investigated mortality rates and causes of death in a cohort of female population from 1st of January 2010 to 31st of December 2012. At the baseline, 33,688 females were involved for the prospective follow-up study. Households under the study were updated every six months by fulltime surveillance data collectors to identify vital events, including deaths. Verbal Autopsy (VA) data were collected by separate trained data collectors for all identified deaths in the surveillance site. Trained physicians assigned underlining causes of death using the 10th edition of International Classification of Diseases (ICD). We assessed overall, age- and cause-specific mortality rates per 1000 person-years. Causes of death among all deceased females and by age groups were ranked based on cause specific mortality rates. Analysis was performed using Stata Version 11.1. During the follow-up period, 105,793.9 person-years of observation were generated, and 398 female deaths were recorded. This gave an overall mortality rate of 3.76 (95% confidence interval (CI): 3.41, 4.15) per 1,000 person-years. The top three broad causes of death were infectious and parasitic diseases (1.40 deaths per 1000 person-years), non-communicable diseases (0.98 deaths per 1000 person-years) and external causes (0.36 per 1000 person-years). Most deaths among reproductive age female were caused by Human Deficiency Virus/Acquired Immune Deficiency Virus (HIV/AIDS) and tuberculosis (0.14 per 1000 person-years for each cause). Pregnancy and childbirth related causes were responsible for few deaths among women of reproductive age--3 out of 73 deaths (4.1%) or 5.34 deaths per 1,000 person

  2. 39 CFR 230.4 - Arrest and investigative powers of criminal investigators.

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Arrest and investigative powers of criminal... OFFICE OF INSPECTOR GENERAL General Policy and Authority § 230.4 Arrest and investigative powers of criminal investigators. (a) Under the authority of 18 U.S.C. 3061, criminal investigators employed by the...

  3. Geological mapping of investigation trench OL-TK19 at the Olkiluoto study site, Eurajoki, SW Finland

    Energy Technology Data Exchange (ETDEWEB)

    Eroma, E.; Nordbaeck, N.; Engstroem, J. [Geological Survey of Finland, Espoo (Finland)

    2014-12-15

    In October 2012, the geological mapping of investigation trench OL-TK19 was carried out by the Geological Survey of Finland at the Olkiluoto study site. The SE-NW trending, ca. 85 m long trench is located in the central part of the Olkiluoto Island next to investigation trenches OL-TK18 and OL-TK4. The lithology in investigation trench OL-TK19 is of heterogeneous character, with rock type varying from veined gneiss, diatexitic gneiss to pegmatitic granite, along with portions of mica gneiss and K-feldspar porphyritic gneiss. In addition, inclusions of mica gneiss, quartz gneiss and skarn are encountered. The rocks have been subjected to a multiphase ductile deformation and the trench is situated in an area where the latest ductile deformation phase, D4 prevails. The investigation trench can be divided into three domains according to its dominant deformation phase and foliation; the eastern part of the trench is dominated by the D3 deformation phase whereas the middle and western parts are dominated by the D4 deformation phase. The S3 foliation has a more ENE-WSW oriented direction whereas the S4 is trending NE-SW. In addition to this difference in orientation, the different structural signature of these two deformation types is observed, the S3 foliation is defined by smaller scaled granitic leucosome veining whereas the S4 foliation is intensely sheared and have a schistose character. During the fracture mapping, all fractures intersecting the central thread were investigated and a total of 132 fractures were recorded. The average fracture frequency 1.53 fractures/m. On the basis of fracture orientations, three fracture sets can be defined. The first set is vertical and NW-SE trending, second set strikes NE-SW with a moderate dip towards the SE and the third set is vertical and NE-SW trending. The median fracture length is 1.38 m and most fractures do not exceed 0.5 m in length, the longest measured fracture being 5.30 m in length. Fracture fillings are mostly

  4. Investigation of film boiling thermal hydraulics under FCI conditions. Results of a numerical study

    Energy Technology Data Exchange (ETDEWEB)

    Dinh, T.N.; Dinh, A.T.; Nourgaliev, R.R.; Sehgal, B.R. [Div. of Nuclear Power Safety Royal Inst. of Tech. (RIT), Brinellvaegen 60, 10044 Stockholm (Sweden)

    1998-01-01

    Film boiling on the surface of a high-temperature melt jet or of a melt particle is one of key phenomena governing the physics of fuel-coolant interactions (FCIs) which may occur during the course of a severe accident in a light water reactor (LWR). A number of experimental and analytical studies have been performed, in the past, to address film boiling heat transfer and the accompanying hydrodynamic aspects. Most of the experiments have, however, been performed for temperature and heat flux conditions, which are significantly lower than the prototypic conditions. For ex-vessel FCIs, high liquid subcooling can significantly affect the FCI thermal hydraulics. Presently, there are large uncertainties in predicting natural-convection film boiling of subcooled liquids on high-temperature surfaces. In this paper, research conducted at the Division of Nuclear Power Safety, Royal Institute of Technology (RIT/NPS), Stockholm, concerning film-boiling thermal hydraulics under FCI condition is presented. Notably, the focus is placed on the effects of (1) water subcooling, (2) high-temperature steam properties, (3) the radiation heat transfer and (4) mixing zone boiling dynamics, on the vapor film characteristics. Numerical investigations are performed using a novel CFD modeling concept named as the local-homogeneous-slip model (LHSM). Results of the analytical and numerical studies are discussed with respect to boiling dynamics under FCI conditions. (author)

  5. Oil-based compositions as saliva substitutes: A pilot study to investigate in-mouth retention.

    Science.gov (United States)

    Hanning, Sara M; Medlicott, Natalie J

    2016-03-30

    This pilot study aimed to compare the in-mouth retention of an oil-based saliva substitute (emulsion, consisting of rice bran oil, soy lecithin and water) with water and a 1% w/v methylcellulose suspension (polymer) in healthy volunteers. Each formulation was tagged with 1 mmol/L lithium and participants (n=30) rinsed their mouth with one randomly assigned formulation (emulsion, polymer or water) for 30s, before expectorating into a cup. Concentration of lithium expectorated was measured and amount of each formulation remaining in the mouth was estimated. Patient acceptability was investigated using questionnaires, and Fourier-Transform Infrared spectroscopy (FTIR) was used to determine the presence of oil in expectorated samples. Immediately after rinsing, taste was rated lower in the emulsion group compared to the polymer or water groups (p>0.05), although variability was high. Mean retention was highest in the emulsion group, with a difference of 8.34 ± 2.71% (p=0.003) and 4.57 ± 2.71% (p=0.06) compared with the water and polymer groups, respectively. FTIR confirmed the presence of oil in all expectorated emulsion samples. The emulsion was not inferior to the polymer in terms of retention immediately after rinsing. The next step is to conduct larger clinical studies over longer time periods in participants with salivary hypofunction. Copyright © 2016 Elsevier B.V. All rights reserved.

  6. VOLTAMMETRIC INVESTIGATION OF THE DISTRIBUTION OF ...

    African Journals Online (AJOL)

    VOLTAMMETRIC INVESTIGATION OF THE DISTRIBUTION OF HYDROXO-, CHLORO-, EDTA AND CARBOHYDRATE COMPLEXES OF LEAD, CHROMIUM, ZINC, CADMIUM AND COPPER: POTENTIAL APPLICATION TO METAL SPECIATION STUDIES IN BREWERY WASTEWATER.

  7. An empirical study to investigate the effects of thinking styles on emotional intelligence: A case study of Jihad Agriculture Organization of east Azerbaijan province

    Directory of Open Access Journals (Sweden)

    Habibeh Ayagh

    2013-05-01

    Full Text Available An empirical study to investigate the effects of thinking styles on emotional intelligence among employees of agriculture industry in east Azerbaijan province. The proposed study uses a standard thinking style questionnaire originally developed by Sternberg and Wagner (1992 [Sternberg, R. J., & Wagner, R. K. (1992. Thinking styles inventory. Unpublished test, Yale University]. There are 716 employees working for this agriculture-based unit and the study uses random sampling technique and chooses 255 employees for this study. Cronbach alpha has been used to verify the overall questionnaire and different tests such as Kolmogorov-Smirnov and Pearson correlation test are used to examine different hypotheses of this survey. The results indicate there is positive and meaningful relationship between thinking style and emotional intelligence. We can also confirm that four thinking style’s components including functions, levels, scope and learning have meaningful impact on emotional intelligence when the level of significance is five or even one percent. However, forms did not have any meaningful impact on emotional intelligence.

  8. Online market research panel members as controls in case-control studies to investigate gastrointestinal disease outbreaks: early experiences and lessons learnt from the UK.

    Science.gov (United States)

    Mook, P; McCormick, J; Kanagarajah, S; Adak, G K; Cleary, P; Elson, R; Gobin, M; Hawker, J; Inns, T; Sinclair, C; Trienekens, S C M; Vivancos, R; McCarthy, N D

    2018-03-01

    Established methods of recruiting population controls for case-control studies to investigate gastrointestinal disease outbreaks can be time consuming, resulting in delays in identifying the source or vehicle of infection. After an initial evaluation of using online market research panel members as controls in a case-control study to investigate a Salmonella outbreak in 2013, this method was applied in four further studies in the UK between 2014 and 2016. We used data from all five studies and interviews with members of each outbreak control team and market research panel provider to review operational issues, evaluate risk of bias in this approach and consider methods to reduce confounding and bias. The investigators of each outbreak reported likely time and cost savings from using market research controls. There were systematic differences between case and control groups in some studies but no evidence that conclusions on the likely source or vehicle of infection were incorrect. Potential selection biases introduced by using this sampling frame and the low response rate are unclear. Methods that might reduce confounding and some bias should be balanced with concerns for overmatching. Further evaluation of this approach using comparisons with traditional methods and population-based exposure survey data is recommended.

  9. An Exploratory Study Investigating the Non-Clinical Benefits of Evidence-Based Veterinary Medicine

    Directory of Open Access Journals (Sweden)

    Elizabeth Jackson

    2017-05-01

    Full Text Available Objective: As little prior research exists about the non-clinical benefits of evidence-based veterinary medicine (EBVM, this exploratory study was conducted to identify non-clinical benefits of EBVM to veterinary practices, as well as highlighting the barriers to further implementation, and ways to overcome them.Background: A PICO-based literature review (Hauser and Jackson, 2016 was conducted to establish current knowledge about the non-clinical benefits of EBVM. It found that while there are some papers suggesting a link between the practice of EBVM and better non-clinical benefits such as client satisfaction and client retention, a single study, focusing on the non-clinical benefits of EBVM, had yet to be conducted.Evidentiary value: This exploratory study provides a solid basis for the further development of a confirmatory study of the themes identified in the interviews. The impact on practice from our findings is significant as it details the key areas where the use of EBVM can yield commercial benefits from the perspective of a group of EBVM experts via interview. It is entirely possible that international veterinary environments which mirror that of the UK will find this research beneficial.Methods: Due to the paucity of data about the non-clinical benefits of EBVM, an exploratory, qualitative approach was taken to this research in order to build a platform for further confirmatory, quantitative investigation (Zikmund, 2003. In February and March 2016 interviews with 16 RCVS Knowledge Group chairs[1] were conducted. The interview guide contained broad, open-ended questions to explore existing tacit knowledge about the non-commercial benefits of EBVM. The interviews were audio recorded and transcribed verbatim and subsequently analysed using NVivo 11 software.Results: This qualitative enquiry showed that the key areas where the use of EBVM can yield non-clinical benefits are through increased client satisfaction and retention, improved

  10. Investigation and feasibility study of a former manufactured gas plant site in Tuttlingen (Germany), based on individually determined clean-up criteria

    Energy Technology Data Exchange (ETDEWEB)

    Heinecker, C.; Pickel, H.-J.; Duffek, J. [HPC Harress Pickel Consult GmbH, Fuldatal (Germany)

    1995-12-31

    At the request of the former plant operator, a manufactured gas plant site in Tuttlingen, Germany, was investigated from 1988 through 1992 for subsurface soil contamination resulting from former activities. In 1991, the contents of the former tar pits and parts of the adjacent soil contaminations were removed in the course of clean-up activities by means of excavation and disposed at a special waste site. Following an initial risk assessment, a remedial investigation was carried out in order to further delineate the contaminated areas as well as to create a reliable database for a feasibility study of remedial alternatives. The feasibility study followed applicable Baden-Wurttemberg state guidelines, including the following elements: Determination of the clean-up goals for soils; pre-selection of the clean-up procedure; cost estimate; cost-effectiveness study; Non-monetary evaluation; and total evaluation/clean-up proposal. The following general alternatives were available for the definition of clean-up goals: background values (`H-values`); general guidelines values (`SZ-values`); and clean-up goals based on contaminant fate and transport as well as site use (`SZA-values`).

  11. Thermogravimetric investigations of vanadium complexes

    International Nuclear Information System (INIS)

    Bechmann, W.; Uhlemann, E.; Ludwig, W.

    1987-01-01

    Extensive studies on oxovanadium(IV) and (V) complexes with bidentate chelating ligands include thermogravimetric investigations. TG, DTG, and DTA data provide additional facts to redox behaviour and stability of the complexes. These data also allow a critical appreciation of the given melting temperatures. (author)

  12. The Allergic Rhinitis Clinical Investigator Collaborative (AR-CIC): verification of nasal allergen challenge procedures in a study utilizing an investigational immunotherapy for cat allergy.

    Science.gov (United States)

    Neighbour, Helen; Soliman, Mena; Steacy, Lisa M; Hickey, Pascal; Forbes, Beth; Larché, Mark; Ellis, Anne K

    2018-01-01

    The Allergic Rhinitis Clinical Investigator Collaborative (AR-CIC) is a network of experienced Allergic Rhinitis (AR) researchers developing better research tools based on the nasal allergen challenge (NAC). A key objective of such is the ability to detect efficacy in a small population. AR-CIC sought to test its NAC protocol as a secondary objective in two small mechanistic research trials of a novel form of immunotherapy [Cat Peptide Antigen Desensitisation (Cat-PAD)] for which efficacy had previously been demonstrated. The primary objective (not presented here) was to identify potential biomarkers of efficacy for peptide immunotherapy, and this provided an ideal opportunity to corroborate the NAC protocol. We aim to clinically validate the AR-CIC NAC methodology in a pooled analysis of secondary endpoints measured in two open label mechanistic studies of cat allergic participants treated with Cat-PAD. Cat allergic AR sufferers with ongoing cat exposure were included. Participants had to demonstrate a total nasal symptom score (TNSS) of at least 8 (max 12) and/or achieve a reduction in peak nasal inspiratory flow (PNIF) of ≥ 50% during a screening titrated NAC. Eligible participants then underwent a baseline NAC visit with the allergen dose that produced a positive challenge at screening, followed by four monthly injections of 6 nmol Cat-PAD. A follow up NAC visit documented changes in nasal response 1 month following the completion of treatment. Nineteen subjects completed the study protocol in the two studies combined. Four injections of Cat-PAD resulted in a significant reduction in TNSS responses generated via NAC following allergen challenge (15 min p  < 0.05, 30 min p  < 0.05, 1 h p  < 0.01, 2 h p  < 0.05). There was modest correlation between symptom scores and PNIF measurements. This study supports the validity of the AR-CIC's optimised NAC protocol for conducting research of the potential efficacy of novel therapeutics in multi

  13. Investigating the Concentration of Heavy Metals in Bottled Water and Comparing with its Standard: Case Study

    Directory of Open Access Journals (Sweden)

    Mohammad Hossien Salmani

    2017-09-01

    Results: Brand No. 1, the concentration of zinc ion was larger in Brand 2 while in Brand No. 2 had larger copper, nickel, and aluminum ions. The results indicated that the concentration of the measured metal ions were below the allowable limit of drinking water standard across all of the studied samples. Conclusion: Based on the obtained results from the investigated parameters, it can be concluded that the bottled water of both brands poses no health issue and is drinkable. Considering the changes in the concentration of ions and the increasing trend of consumption of bottled waters, their monitoring and qualitative control of pollutants are very crucial in terms of public health.

  14. INVESTIGATING THE LEVEL OF BURNOUT AND INFLUENCING FACTORS ON IT AMONG THE WORKERS: CASE STUDY THE PETROCHEMICAL INDUSTRIES NATIONAL COMPANY

    Directory of Open Access Journals (Sweden)

    Hassan DARVISH

    2011-01-01

    Full Text Available This study is done with the purpose of investigation the level of burnout andinfluencing factors on it. The method used is measuring or filed-finding,descriptive studies type and the statistic society is made of the entire officialand non-official workers in the petrochemical industries national company inthe year (2009 including 6901people in the main office and 12 subsidiarycompanies who are working. The estimation of the sample volume is madeusing the cochran formula by the volume of 1742 people and the accidentalclass and the domesticated form of the Maslach Burn Out Inventory has beenused for gathering the dependant variant data of the study. In this study therelevance or effect of 20 independent variables on the burnout and itsconstituents was investigated. In the two variable tests, the emotionalcommitment had a reverse relation with burnout. So that with the increase ofthe interest and bind of the workers to the organization, the level of burnoutdecreased. In analyzing the step by step regression of the burnout accordingto the expected variables, 41percent of the explained burnout (R 2 =41%,and ranking the amount of the standard coefficient, the main elements likethe nature of the job, emotional commitment, work environment, job security,coworkers, education, job type, salary and the premium and jobindependence in the remaining regression equation and on the burnoutvariable have been influencing.

  15. An investigation of drug binding ability of a surface active ionic liquid: micellization, electrochemical, and spectroscopic studies.

    Science.gov (United States)

    Mahajan, Suruchi; Sharma, Rabia; Mahajan, Rakesh Kumar

    2012-12-18

    Keeping in view the use of surfactants in drug delivery, the interactions of surface active ionic liquids, such as 1-tetradecyl-3-methylimidazolium bromide (C(14)mimBr), with drugs, viz., dopamine hydrochloride (DH) and acetylcholine chloride (AC), have been studied, and the results are further compared with that of the structurally similar conventional cationic surfactant tetradecyltrimethylammonium bromide (TTAB). The micellization and interfacial behavior of C(14)mimBr and TTAB, in the presence of DH and AC, has been investigated from conductivity and surface tension measurements. Various micellar and adsorption characteristics for these drug-surfactant systems (DH/AC + C(14)mimBr/TTAB) have been investigated, indicating favorable interactions between them. The more detailed information regarding the nature of interactions between C(14)mimBr/TTAB and DH/AC is obtained from cyclic voltammetry (CV) and (1)H NMR measurements. CV measurements have been employed to evaluate the binding constant (K) and the Gibbs free energy change (ΔG) for these drug-surfactant complexes. These measurements indicate the existence of cation-π as well as π-π interactions between drugs and surfactants. A detailed analysis of chemical shifts of protons of drug molecules (DH and AC) in the presence of C(14)mimBr and TTAB has been done by (1)H NMR. The results obtained from (1)H NMR are in agreement with those of CV measurements. (1)H NMR studies along with the conductivity and surface tension measurements help in predicting the possible location of adsorption of these drug molecules in C(14)mimBr and TTAB micelles.

  16. Protein supplements and adolescent athletes: A pilot study investigating the risk knowledge, motivations and prevalence of use.

    Science.gov (United States)

    Whitehouse, Gavin; Lawlis, Tanya

    2017-11-01

    Protein-based sports supplements are among the more common types of nutrition supplements consumed by athletes; however, there is currently limited data investigating the knowledge, motivations and occurrence of use among the adolescent population (13-18 years). This pilot study looks to obtain initial data regarding the use of protein supplements in this population. This study investigates the understanding and occurrence of protein supplement use in 87 adolescent athletes based in an Australian capital city who compete in a variety of sports. Sources of information, regularity of use, purchasing habits, associated risk knowledge and supplement beliefs were examined using a self-reported, written questionnaire. A total of 60% (n = 52) of athletes reported using protein supplements, with a positive relationship between age and use (P supplement consumption, with the most common risk reported as 'I don't know' (22%). Coaches were found to initiate protein supplement use more than other figures in the athlete's life (50%) and were the primary source of information regarding supplements (58%). It was found that 19% of adolescent athletes obtained information about protein supplements from the Internet, and 17% of all consumers purchase their supplements online. The evident lack of knowledge regarding protein supplements demonstrates a necessity for further education of athletes, coaches and families regarding the responsible purchasing and use of protein supplements in the current landscape of sports nutrition. Future research should further explore the role of the Internet in protein supplement purchase and education. © 2017 Dietitians Association of Australia.

  17. Computer application in scientific investigations

    International Nuclear Information System (INIS)

    Govorun, N.N.

    1981-01-01

    A short review of the computer development and application and software in JINR for the last 15 years is presented. Main trends of studies on computer application in experimental and theoretical investigations are enumerated: software of computers and their systems, software of data processing systems, designing automatic and automized systems for measuring track detectors images, development of technique of carrying out experiments on computer line, packets of applied computer codes and specialized systems. The development of the on line technique is successfully used in investigations of nuclear processes at relativistic energies. The new trend is the development of television methods of data output and its computer recording [ru

  18. Accident investigation practices in Europe--main responses from a recent study of accidents in industry and transport.

    Science.gov (United States)

    Roed-Larsen, Sverre; Valvisto, T; Harms-Ringdahl, L; Kirchsteiger, C

    2004-07-26

    Europe has during recent years been shocked by disasters from natural events and technical breakdowns. The consequences have been comprehensive, measured by lost lives, injuries, and material and environmental damage. ESReDA wanted in 2000--by setting up a special expert group on accident investigation--to clarify the state of art of accident investigation practices and to map the use of thoroughly accident investigation in order to learn lessons from past disasters and prevent new ones. The scope was to cover three sectors in the society: transport, production processes and storage of hazardous materials, and energy production. The main method used was a questionnaire, which was sent in 2001 to about 150 organisations. About 50 replies were analysed. The replies showed great variations but also similarities, among others in definition of accident and incident, the objectives of the investigation team, criteria used to start an investigation, the status of the investigation organisation, the flow of information, the composition of the investigation team, and the use of internal or international procedures or rules. Several methods (in total 14 different methods were mentioned) were used for carrying out accident /incident investigations. Most of the respondents were willing to co-operate in one or another way with ESReDA. Although there are important biases in the material, the results from questionnaire are important inputs to the future work of ESReDA Expert group in this field. 3 safety approaches have been identified.

  19. The Use of ExoSeal Vascular Closure Device for Direct Antegrade Superficial Femoral Artery Puncture Site Hemostasis

    Energy Technology Data Exchange (ETDEWEB)

    Rimon, Uri, E-mail: rimonu@sheba.health.gov.il; Khaitovich, Boris, E-mail: borislena@012.net.il [Tel-Aviv University, Diagnostic and Interventional Imaging Department, Chaim Sheba Medical Center, Tel-Hashomer, Affiliated to the Sackler School of Medicine (Israel); Yakubovich, Dmitry, E-mail: Dmitry.Yakubovitch@sheba.health.gov.il [Tel-Aviv University, Vascular Surgery Department, Chaim Sheba Medical Center, Tel-Hashomer, Affiliated to the Sackler School of Medicine (Israel); Bensaid, Paul, E-mail: paulbensaid@hotmail.com; Golan, Gil, E-mail: gilgolan201@gmail.com [Tel-Aviv University, Diagnostic and Interventional Imaging Department, Chaim Sheba Medical Center, Tel-Hashomer, Affiliated to the Sackler School of Medicine (Israel); Silverberg, Daniel, E-mail: Daniel.Silverberg@sheba.health.gov.il [Tel-Aviv University, Vascular Surgery Department, Chaim Sheba Medical Center, Tel-Hashomer, Affiliated to the Sackler School of Medicine (Israel)

    2015-06-15

    PurposeThis study was designed to assess the efficacy and safety of the ExoSeal vascular closure device (VCD) to achieve hemostasis in antegrade access of the superficial femoral artery (SFA).MethodsWe retrospectively reviewed the outcome of ExoSeal VCD used for hemostasis in 110 accesses to the SFA in 93 patients between July 2011 and July 2013. All patients had patent proximal SFA based on computer tomography angiography or ultrasound duplex. Arterial calcifications at puncture site were graded using fluoroscopy. The SFA was accessed in an antegrade fashion with ultrasound or fluoroscopic guidance. In all patients, 5–7F vascular sheaths were used. The ExoSeal VCD was applied to achieve hemostasis at the end of the procedure. All patients were clinically examined and had ultrasound duplex exam for any puncture site complications during the 24 h postprocedure.ResultsIn all procedures, the ExoSeal was applied successfully. We did not encounter any device-related technical failure. There were four major complications in four patients (3.6 %): three pseudoaneurysms, which were treated with direct thrombin injection, and one hematoma, which necessitated transfusion of two blood units. All patients with complications were treated with anticoagulation preprocedure or received thrombolytic therapy.ConclusionsThe ExoSeal VCD can be safely used for antegrade puncture of the SFA, with a high procedural success rate (100 %) and a low rate of access site complications (3.6 %)

  20. Studies of quaternary deposits of investigation trench OL-TK13 at the Olkiluoto study site, Eurajoki, SW Finland

    Energy Technology Data Exchange (ETDEWEB)

    Huhta, P. [Geological Survey of Finland, Espoo (Finland)

    2007-05-15

    The Quaternary deposits in investigation trench OL-TK13 were studied by the Geological Survey of Finland in autumn 2006. The investigations were carried out in three phases as the excavation progressed. Samples for grain size determinations were taken from vertical profiles, placed 25 m apart along the trench. The profiles extended from the soil surface down to bedrock or, if the bedrock was covered with water, to the water table. Between 6 and 7 kg of sediment was taken in a bucket with a shovel and placed in plastic bags for transport to the laboratory. The samples were first dried in the laboratory after which they were sieved. In addition, grain size distribution of the < 63 {mu}m fraction was analyzed with the Sedigraph 5100 instrument. Sedimentological observations of the sampling profiles were documented in field by drawing on a field observation form and the profiles were photographed using a digital camera except profiles 7 and 8. In addition, the excavated section was photographed along their whole length. The length of OL-TK13 is approximately 250 m and 11 profiles were studied. The height of the profiles varied from 7.3 m to 2.3 m, with an average of 4.6 m. The till cover in OL-TK13 consist of two parts. The upper till has three layers. Surface layer is oxidized, brown sandy till, which is underlain by grayish brown intermediate layer of sandy till. This layer represents the grounwater table, which is moving up and down. The lower layer is unoxidized, grey sandy till. The thickness of the upper till varies from 2.3 to 5.5 meters. The upper till in OL-TK13 is classified as having a normal amount of cobbles and boulders with the size of the larger clasts varying from 6 to 60 cm. The edges of clasts have been eroded and rounded. The upper till has normal compactness. The lower till has been spared in bedrock depressions. Part of it's material has ascended the upper till. The lower till is compact, dark grey silty till with over 15 % of fine material

  1. Studies of quaternary deposits of investigation trench OL-TK13 at the Olkiluoto study site, Eurajoki, SW Finland

    International Nuclear Information System (INIS)

    Huhta, P.

    2007-05-01

    The Quaternary deposits in investigation trench OL-TK13 were studied by the Geological Survey of Finland in autumn 2006. The investigations were carried out in three phases as the excavation progressed. Samples for grain size determinations were taken from vertical profiles, placed 25 m apart along the trench. The profiles extended from the soil surface down to bedrock or, if the bedrock was covered with water, to the water table. Between 6 and 7 kg of sediment was taken in a bucket with a shovel and placed in plastic bags for transport to the laboratory. The samples were first dried in the laboratory after which they were sieved. In addition, grain size distribution of the < 63 μm fraction was analyzed with the Sedigraph 5100 instrument. Sedimentological observations of the sampling profiles were documented in field by drawing on a field observation form and the profiles were photographed using a digital camera except profiles 7 and 8. In addition, the excavated section was photographed along their whole length. The length of OL-TK13 is approximately 250 m and 11 profiles were studied. The height of the profiles varied from 7.3 m to 2.3 m, with an average of 4.6 m. The till cover in OL-TK13 consist of two parts. The upper till has three layers. Surface layer is oxidized, brown sandy till, which is underlain by grayish brown intermediate layer of sandy till. This layer represents the grounwater table, which is moving up and down. The lower layer is unoxidized, grey sandy till. The thickness of the upper till varies from 2.3 to 5.5 meters. The upper till in OL-TK13 is classified as having a normal amount of cobbles and boulders with the size of the larger clasts varying from 6 to 60 cm. The edges of clasts have been eroded and rounded. The upper till has normal compactness. The lower till has been spared in bedrock depressions. Part of it's material has ascended the upper till. The lower till is compact, dark grey silty till with over 15 % of fine material (under 0

  2. [Orion (Outbreak Reports and Intervention studies of Nosocomial Infection) used for evaluating interventions and investigations of nosocomial infection outbreaks].

    Science.gov (United States)

    Pires-Cronenberger, S; Nicolle, M-C; Voirin, N; Giard, M; Luxemburger, C; Vanhems, P

    2009-04-01

    British colleagues have developed the Outbreak Reports and Intervention studies of Nosocomial Infection (Orion) guidelines with the aim to promote transparency of publications in the field of health-care associated infections and particularly for reports of outbreak investigation or intervention studies. The aim of this study was to translate the Orion criteria and to promote their use in France. The Orion guidelines include a checklist of 22 commented items related to the title, abstract, introduction, methods, results, and discussion sections of a scientific article. Specific points for each item are developed to enhance its relevance. The use of Orion guidelines by authors and editors should be encouraged and should improve the quality of standards in research, intervention studies, and publications on nosocomial infections and health-care associated infections.

  3. 42 CFR 93.215 - Investigation.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Investigation. 93.215 Section 93.215 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH...

  4. An investigation on the relationship between arbitrage and macro-economic indicators: A case study of Tehran Stock Exchange

    Directory of Open Access Journals (Sweden)

    Samira Fazli

    2014-04-01

    Full Text Available This paper presents an empirical investigation to study the effects of macro-economic factors on the performance of stocks listed on Tehran Stock Exchange (TSE. The proposed study considers the effects of money supply, inflation rate, oil price, unforeseen changes in the course structure of interest rates as well as unanticipated changes in industrial production on stock price. Using seasonal information of stock price over the period 1997-2007 as well as regression analysis, the study has determined that risk premium of unforeseen changes in the course structure of interest rates, money supply, inflation rate and unanticipated changes in industrial production are meaningful when the level of significance is five percent. In other words, Arbitrage pricing theory model describing the expected return per share is reasonable and macro-level variables explain systematic risk on TSE.

  5. The study of chromosome aberration yield in human lymphocytes as an indicator of radiation dose. 3. A review of cases investigated: 1971-72

    International Nuclear Information System (INIS)

    Purrott, R.J.; Lloyd, D.C.; Dolphin, G.W.; Eltham, E.J.; Platt, S.K.; Tipper, P.A.; Strange, C.M.

    1973-02-01

    Results from cytogenetic investigations into 54 cases of suspected overexposure to radiation are reviewed. This report is a sequel to NRPB-R5 which contained data from the first 41 studies; results from all 95 investigations have been pooled for general analysis. Brief accounts are given of the circumstances behind the 54 later investigations and where possible physical estimates of dose have been included for comparison. From data on lymphocyte half-life obtained in the first series of cases, an attempt has been made to allow for the loss of damaged cells where the exposure occurred some years previously. The presence of incomplete chromosome damage appears to be characteristic of exposures which occurred some years ago. The ratio of dicentrics to acentrics observed in the accident investigation has been compared with that obtained in recent research studies. The problem of interpreting aberration yield in cases of exposure to kV non-penetrating radiation and to partial body doses, such as to fingers, has been discussed. In addition the problem of selective irradiation of lymphocytes by internally incorporated radionuclides in, for example, lymph nodes and highly vascular tissue, has been examined. Difficulties have been encountered in culturing leukaemic lymphocytes. These and other areas of research which would benefit cytogenetic dosimetry are discussed. (author)

  6. Incidence and risk factors for surgically acquired pressure ulcers: a prospective cohort study investigators.

    Science.gov (United States)

    Webster, Joan; Lister, Carolyn; Corry, Jean; Holland, Michelle; Coleman, Kerrie; Marquart, Louise

    2015-01-01

    To assess the incidence of hospital-acquired, surgery-related pressure injury (ulcers) and identify risk factors for these injuries. We used a prospective cohort study to investigate the research question. The study was conducted at a major metropolitan hospital in Brisbane, Australia. Five hundred thirty-four adult patients booked for any surgical procedure expected to last more than 30 minutes were eligible for inclusion. Patients who provided informed consent for study participation were assessed for pressure ulcers, using the European Pressure Ulcer Advisory Panel and National Pressure Ulcer Advisory Panel Guidelines, before entering the operating room and again in the post-anesthetic care unit (PACU). Research nurses and all PACU nurses were trained in skin assessment and in pressure ulcer staging. Patients were not assessed again after their discharge from the PACU. Seven patients (1.3%) had existing pressure injuries (ulcers) and a further 6 (1.3%) developed a surgery-related pressure ulcer. Risk factors associated with surgery-related pressure injuries were similar to non-surgically related risks and included older age, skin condition, and being admitted from a location other than one's own home. Length of surgery was not associated with pressure ulcer development in this cohort. Perioperative nurses play an important role in identifying existing or new pressure injuries. However, many of these nurses are unfamiliar with pressure ulcer classification, so education in this area is essential. Although the incidence of surgically acquired pressure ulcers was low in this cohort, careful skin inspection before and after surgery provides an opportunity for early treatment and may prevent existing lesions progressing to higher stages.

  7. INFORMATION TECHNOLOGY, KNOWLEDGE CREATION AND SHARING: A STUDY OF THE INTEGRATED PUBLIC SAFETY SYSTEM IN THE BOARD OF CRIMINAL INVESTIGATIONS IN SANTA CATARINA

    Directory of Open Access Journals (Sweden)

    Indianara Silva

    2014-07-01

    Full Text Available The aim of this study is to analyze the role of information technology in the field of operation of public safety in the Brazilian state of Santa Catarina. More specifically, it was based on the following research problem: how does the use of information technology in the area of public safety influence the creation and sharing of knowledge in criminal investigations in the civilian police force, by means of police inquiry? From a methodological point of view, the study was conducted using a qualitative approach, having the character of a case study. The data collection techniques included the use of questionnaires, semi-structured interviews and the analysis of documentation and physical artifacts. As far as the treatment and interpretation of the data is concerned, content analysis techniques were employed. The study showed that the use of information technology can provide actions which facilitate sharing, mainly of explicit knowledge, and which, as a result, characterize activities related to criminal investigation and the launching of police inquiries. These activities are lacking in strategies that provide the sharing of tacit knowledge and consequently the creation of knowledge. Moreover, it was found that the contribution of technology to knowledge creation and sharing in the criminal investigation process also depends on other variables of a contextual (e.g. institutional policies and individual nature (e.g. resistance.

  8. Guadalupe River, California, Sedimentation Study. Numerical Model Investigation

    National Research Council Canada - National Science Library

    Copeland, Ronald

    2002-01-01

    A numerical model study was conducted to evaluate the potential impact that the Guadalupe River flood-control project would have on channel stability in terms of channel aggradation and degradation...

  9. Remedial investigation/feasibility study of the Clinch River/Poplar Creek Operable Unit. Volume 3. Risk assessment information. Appendixes E, F

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    This report presents the findings of an investigation into contamination of the Clinch River and Poplar Creek near the U.S. Department of Energy`s (DOE`s) Oak Ridge Reservation (ORR) in eastern Tennessee. For more than 50 years, various hazardous and radioactive substances have been released to the environment as a result of operations and waste management activities at the ORR. In 1989, the ORR was placed on the National Priorities List (NPL), established and maintained under the federal Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). Under CERCLA, NPL sites must be investigated to determine the nature and extent of contamination at the site, assess the risk to human health and the environment posed by the site, and, if necessary, identify feasible remedial alternatives that could be used to clean the site and reduce risk. To facilitate the overall environmental restoration effort at the ORR, CERCLA activities are being implemented individually as distinct operable units (OUs). This document is Volume 3 of the combined Remedial Investigation and Feasibility Study Report for the Clinch River/Poplar Creek OU.

  10. Systematic investigation and in vitro biocompatibility studies on mesoporous europium doped hydroxyapatite

    OpenAIRE

    Popa Cristina; Ciobanu Carmen; Iconaru Simona; Stan Miruna; Dinischiotu Anca; Negrila Constantin; Motelica-Heino Mikael; Guegan Regis; Predoi Daniela

    2014-01-01

    International audience; This paper reports a systematic investigation on europium doped hydroxyapatite (Eu:HAp). In this work, a set of complementary techniques Fourier Transform Infrared spectroscopy (FTIR), X-ray photoelectron spectroscopy (XPS), transmission electron microscopy (TEM) and, Brunauer-Emmett-Teller (BET) technique was used to allowing a proper understanding of Eu:HAp. The XPS analysis confirmed the substitution of Ca ions by Eu ions in Eu:HAp samples. Eu:HAp and pure HAp show ...

  11. Investigative study on the technical code requirements of natural events hazards for nuclear power plants

    International Nuclear Information System (INIS)

    Ito, Kunio; Aoki, Takayuki

    2012-01-01

    Technical codes and standards on natural phenomena, in particular, earthquake and tsunami for nuclear power plants in the other developed countries including IAEA safety standards were investigated. Then, the results were compared with the corresponding Japanese technical codes and standards. As a results, it was found that: (1) technical codes and standards on natural phenomena, especially those for earthquakes and tsunami/flooding in those foreign countries and their requirements are all included in the Japanese technical codes and standards. (2) Nevertheless, the actual measures against tsunami/flooding in those foreign countries are more advanced than those in Japan which had been taken before Fukushima accident. Therefore, further investigation is needed to clarify the reason why there are such differences by investigating the details of the basic ideas and evaluation methods for the protection of tsunami/flooding. (author)

  12. Remedial investigation/feasibility study work plan for the 100-BC-2 operable unit, Hanford Site, Richland, Washington

    International Nuclear Information System (INIS)

    1993-05-01

    This work plan and attached supporting project plans establish the operable unit setting and the objectives, procedures, tasks, and schedule for conducting the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA) remedial investigation/feasibility study (RI/FS) for the 100-BC-2 operable unit in the 100 Area of the Hanford Site. The 100 Area is one of four areas at the Hanford Site that are on the US Environmental Protection Agency's (EPA) National Priorities List under CERCLA. The 100-BC-2 operable unit is one of two source operable units in the 100-B/C Area (Figure ES-1). Source operable units are those that contain facilities and unplanned release sites that are potential sources of hazardous substance contamination. The 100-BC-2 source operable unit contains waste sites that were formerly in the 100-BC-2, 100-BC-3, and 100-BC-4 operable units. Because of their size and geographic location, the waste sites from these two operable units were added to 100-BC-2. This allows for a more efficient and effective investigation of the remaining 100-B/C Reactor area waste sites. The investigative approach to waste sites associated with the 100-BC-2 operable unit are listed in Table ES-1. The waste sites fall into three general categories: high priority liquid waste disposal sites, low priority liquid waste disposal sites, and solid waste burial grounds. Several sites have been identified as candidates for conducting an IRM. Two sites have been identified as warranting additional limited field sampling. The two sites are the 116-C-2A pluto crib, and the 116-C-2C sand filter

  13. Investigation of Collimator Influential Parameter on SPECT Image Quality: a Monte Carlo Study

    Directory of Open Access Journals (Sweden)

    Banari Bahnamiri Sh

    2015-03-01

    Full Text Available Background: Obtaining high quality images in Single Photon Emission Tomography (SPECT device is the most important goal in nuclear medicine. Because if image quality is low, the possibility of making a mistake in diagnosing and treating the patient will rise. Studying effective factors in spatial resolution of imaging systems is thus deemed to be vital. One of the most important factors in SPECT imaging in nuclear medicine is the use of an appropriate collimator for a certain radiopharmaceutical feature in order to create the best image as it can be effective in the quantity of Full Width at Half Maximum (FWHM which is the main parameter in spatial resolution. Method: In this research, the simulation of the detector and collimator of SPECT imaging device, Model HD3 made by Philips Co. and the investigation of important factors on the collimator were carried out using MCNP-4c code. Results: The results of the experimental measurments and simulation calculations revealed a relative difference of less than 5% leading to the confirmation of the accuracy of conducted simulation MCNP code calculation. Conclusion: This is the first essential step in the design and modelling of new collimators used for creating high quality images in nuclear medicine

  14. Astrobiology as a framework for investigating antibiotic susceptibility: a study of Halomonas hydrothermalis.

    Science.gov (United States)

    Harrison, Jesse P; Angel, Roey; Cockell, Charles S

    2017-01-01

    Physical and chemical boundaries for microbial multiplication on Earth are strongly influenced by interactions between environmental extremes. However, little is known about how interactions between multiple stress parameters affect the sensitivity of microorganisms to antibiotics. Here, we assessed how 12 distinct permutations of salinity, availability of an essential nutrient (iron) and atmospheric composition (aerobic or microaerobic) affect the susceptibility of a polyextremotolerant bacterium, Halomonas hydrothermalis, to ampicillin, kanamycin and ofloxacin. While salinity had a significant impact on sensitivity to all three antibiotics (as shown by turbidimetric analyses), the nature of this impact was modified by iron availability and the ambient gas composition, with differing effects observed for each compound. These two parameters were found to be of particular importance when considered in combination and, in the case of ampicillin, had a stronger combined influence on antibiotic tolerance than salinity. Our data show how investigating microbial responses to multiple extremes, which are more representative of natural habitats than single extremes, can improve our understanding of the effects of antimicrobial compounds and suggest how studies of habitability, motivated by the desire to map the limits of life, can be used to systematically assess the effectiveness of antibiotics. © 2017 The Author(s).

  15. Important Issues in Ecotoxicological Investigations Using Earthworms.

    Science.gov (United States)

    Velki, Mirna; Ečimović, Sandra

    The importance and beneficial effects of earthworms on soil structure and quality is well-established. In addition, earthworms have proved to be important model organisms for investigation of pollutant effects on soil ecosystems. In ecotoxicological investigations effects of various pollutants on earthworms were assessed. But some important issues regarding the effects of pollutants on earthworms still need to be comprehensively addressed. In this review several issues relevant to soil ecotoxicological investigations using earthworms are emphasized and guidelines that should be adopted in ecotoxicological investigations using earthworms are given. The inclusion of these guidelines in ecotoxicological studies will contribute to the better quantification of impacts of pollutants and will allow more accurate prediction of the real field effects of pollutants to earthworms.

  16. Remedial investigation/feasibility study of the Clinch River/Poplar Creek Operable Unit. Volume 4. Appendixes G, H, and I and information related to the feasibility study and ARARs

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-06-01

    This report presents the findings of an investigation into contamination of the Clinch River and Poplar Creek near the U.S. Department of Energy`s (DOE`s) Oak Ridge Reservation (ORR) in eastern Tennessee. For more than 50 years, various hazardous and radioactive substances have been released to the environment as a result of operations and waste management activities at the ORR. In 1989, the ORR was placed on the National Priorities List (NPL), established and maintained under the federal Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). Under CERCLA, NPL sites must be investigated to determine the nature and extent of contamination at the site, assess the risk to human health and the environment posed by the site, and, if necessary, identify feasible remedial alternatives that could be used to clean the site and reduce risk. To facilitate the overall environmental restoration effort at the ORR, CERCLA activities are being implemented individually as distinct operable units (OUs). This document is Volume 4 of the combined Remedial Investigation and Feasibility Study Report for the Clinch River/Poplar Creek OU.

  17. Early-Onset Paternal Smoking and Offspring Adiposity: Further Investigation of a Potential Intergenerational Effect Using the HUNT Study.

    Directory of Open Access Journals (Sweden)

    David Carslake

    Full Text Available Recently it has been suggested that rearing conditions during preadolescence in one generation may affect health outcomes in subsequent generations. Such parental effects, potentially induced by epigenetic modifications in the germ line, have attracted considerable attention because of their implications for public health and social policies. Yet, to date, evidence in humans has been rare due to data limitations and much further investigation in large studies is required. The aim of this paper is to reproduce and extend a recent study which found that paternal smoking before age 11 was associated with elevated body mass index (BMI among male offspring in the Avon Longitudinal Study of Parents and Children (ALSPAC. Using the Nord-Trøndelag Health (HUNT Study, we find that paternal smoking during pre-adolescence (45,000 offspring, we cannot rule out a weaker association, perhaps common to sons and daughters, which would be consistent with the ALSPAC study. Alternatively, we discuss whether confounding, chance in parallel tests, or sample selection effects might explain the observed associations of early paternal smoking with offspring BMI.

  18. Student reasoning while investigating plant material

    Directory of Open Access Journals (Sweden)

    Helena Näs

    2008-11-01

    Full Text Available In this project, 10-12 year old students in three classes, investigated plant material to learn more about plants and photosynthesis. The research study was conducted to reveal the students’ scientific reasoning during their work. The eleven different tasks helped students investigate plant anatomy, plant physiology, and the gases involved in photosynthesis and respiration. The study was carried out in three ordinary classrooms. The collected data consisted of audio-taped discussions, students’ notebooks, and field notes. Students’ discussions and written work, during the different plant tasks, were analysed to see how the students’ learning and understanding processes developed. The analysis is descriptive and uses categories from a modified general typology of student’s epistemological reasoning. The study shows students’ level of interest in doing the tasks, their struggle with new words and concepts, and how they develop their knowledge about plant physiology. The study confirms thatstudents, in this age group, develop understanding and show an interest in complicated processes in natural science, e.g. photosynthesis.

  19. Investigation of tritium in groundwater at Pickering NGS

    International Nuclear Information System (INIS)

    DeWilde, J.; Yu, L.; Belanger, D.; Wootton, R.; Hansen, K.; McGurk, E.; Teare, A.

    2001-01-01

    Ontario Power Generation Inc. (OPG) investigated tritium in groundwater at the Pickering Nuclear Generating Station (PNGS). The objectives of the study were to evaluate and define the extent of radio-nuclides, primarily tritium, in groundwater, investigate the causes or sources of contamination, determine impacts on the natural environment, and provide recommendations to prevent future discharges. This paper provides an overview of the investigations conducted in 1999 and 2000 to identify the extent of the tritium beneath the site and the potential sources of tritium released to the groundwater. The investigation and findings are summarized with a focus on unique aspects of the investigation, on lessons learned and benefits. Some of the investigative techniques discussed include process assessments, video inspections, hydrostatic and tracer tests, Helium 3 analysis for tritium age dating, deuterium and tritium in soil analysis. The investigative techniques have widespread applications to other nuclear generating stations. (author)

  20. Microbial Dark Matter Investigations: How Microbial Studies Transform Biological Knowledge and Empirically Sketch a Logic of Scientific Discovery

    Science.gov (United States)

    Bernard, Guillaume; Pathmanathan, Jananan S; Lannes, Romain; Lopez, Philippe; Bapteste, Eric

    2018-01-01

    Abstract Microbes are the oldest and most widespread, phylogenetically and metabolically diverse life forms on Earth. However, they have been discovered only 334 years ago, and their diversity started to become seriously investigated even later. For these reasons, microbial studies that unveil novel microbial lineages and processes affecting or involving microbes deeply (and repeatedly) transform knowledge in biology. Considering the quantitative prevalence of taxonomically and functionally unassigned sequences in environmental genomics data sets, and that of uncultured microbes on the planet, we propose that unraveling the microbial dark matter should be identified as a central priority for biologists. Based on former empirical findings of microbial studies, we sketch a logic of discovery with the potential to further highlight the microbial unknowns. PMID:29420719

  1. Investigation of a carbon fiber/epoxy prepreg curing behavior for thick composite materials production: An industrial case-study

    Science.gov (United States)

    Giorgini, Loris; Mazzocchetti, Laura; Minak, Giangiacomo; Dolcini, Enrico

    2012-07-01

    A case-study is presented, in cooperation with RI-BA Composites srl, where the industrial production of a thick part for primary structural application is analysed. The final product is a bulk carbon fiber reinforced object characterized by great dimensions, with thickness ranging between 10mm and 35mm and obtained by Hand-Lay-Up of prepregs. The study shows that prepregs age along the time required for the process work up. Moreover, the isothermal curing investigation of the prepreg used in the production gives some useful hint for the design of a new thermal curing cycle, in order to avoid exotherm problems along the thickness of the object. The effect of the applied curing cycle on thermal properties of the object are reported.

  2. Ureteric Embolization for Lower Urinary Tract Fistulae: Use of Two Amplatzer Vascular Plugs and N-Butyl Cyanoacrylate Employing the 'Sandwich' Technique

    Energy Technology Data Exchange (ETDEWEB)

    Saad, Wael E. A., E-mail: ws6r@virginia.edu; Kalagher, S.; Turba, U. C.; Sabri, S. S.; Park, A.-W.; Stone, J.; Angle, J. F.; Matsumoto, A. H. [University of Virginia Health System, Department of Radiology and Medical Imaging, Division of Vascular Interventional Radiology (United States)

    2013-08-01

    PurposeThis study describes and evaluated the effectiveness of occluding distal ureters in the clinical setting of urinary vaginal (vesicovaginal or enterovesicovaginal) fistulae utilizing a new technique which combines Amplatzer vascular plugs and N-butyl cyanoacrylate.MaterialsThis is a retrospective study (January 2007-December 2010) of patients with urinary-vaginal fistulae undergoing distal ureter embolization utilizing an Amplatzer- N-butyl cyanoacrylate-Amplatzer sandwich technique. An 8-12-mm type-I or type-II Amplatzer vascular plug was delivered using the sheath and deployed in the ureter distal to the pelvic brim. Instillation of 0.8-1.5 cc of N-butyl cyanoacrylate into ureter proximal to the Amplatzer plug was performed. This was followed by another set of 8-12-mm type-I or type-II Amplatzer vascular plugs in a technique referred to as the 'sandwich technique.'ResultsFive ureters in three patients were occluded utilizing the above-described technique during the 4-year study period. Mean maximum size Amplatzer used per ureter was 10.8 mm (range, 8-12). One ureter required three Amplatzer plugs and the rest required two. Two patients (3 ureters) were clinically successful with complete resolution of symptoms in 36-48 h. The third patient (2 ureters) was partly successful and required a second Amplatzer- N-butyl cyanoacrylate sandwich technique embolization. The mean clinical follow-up was 11.3 months (range, 1.7-29.2).ConclusionsThe Amplatzer- N-butyl cyanoacrylate-Amplatzer sandwich technique for occluding the distal ureter is safe and effective with a quick (probably due to the N-butyl cyanoacrylate) and durable (probably due to the Amplatzer plugs) clinical response.

  3. Investigations into the temporal development of epitheliocystis infections in brown trout: a histological study.

    Science.gov (United States)

    Guevara Soto, M; Vidondo, B; Vaughan, L; Rubin, J-F; Segner, H; Samartin, S; Schmidt-Posthaus, H

    2017-06-01

    Epitheliocystis in Swiss brown trout (Salmo trutta) is a chlamydial infection, mainly caused by Candidatus Piscichlamydia salmonis and Candidatus Clavichlamydia salmonicola. To gain a better understanding of the temporal development of infections in wild brown trout, we investigated epitheliocystis infections during the course of the summer and autumn months of a single year (2015), and compared this to sampling points over the span of the years 2012-2014. The survey focused on tributaries (Venoge and Boiron) of the Rhone flowing in to Lake Geneva. When evaluated histologically, epitheliocystis infections were found throughout the period of investigation with the exception of the month of June. Fifty to 86 animals per sampling were investigated. Highest prevalence and infection intensities were seen in September. A correlation between epitheliocystis infection and water temperatures was not evident. Interyear comparison revealed consistent levels of prevalence and infection intensities in late summer. The absence of infections in June, combined with the consistent interyear results, indicates seasonal fluctuation of epitheliocystis infections in brown trout with a reservoir persisting during winter months from which infections can re-initiate each year. This could either be at levels below detection limits within the brown trout population itself or in an alternative host. © 2016 John Wiley & Sons Ltd.

  4. Investigations of the adequacy of the meteorological transport model developed for the reactor safety study

    International Nuclear Information System (INIS)

    Spring, J.L.; Brown, W.D.; Church, H.W.; McGrath, P.E.; Ritchie, L.T.; Russo, A.J.; Steck, G.P.; Wayland, J.R.; Blond, R.M.; Wall, I.B.

    1978-01-01

    A computer model (CRAC) was developed for the Reactor Safety Study (WASH-1400) [1] to estimate the consequences of postulated accidents at U.S. commercial nuclear power plants. One hundred reactors at 68 sites were included in the study. The 68 sites were divided into 6 classes according to their geographic location and meteorology. For each site class, a composite population distribution was constructed from the true population distributions at each of the sites comprising that class, and a reference site was chosen for which a full year of meteorological data (wind speed, atmospheric stability, occurrence of rain) was obtained. Given data about a postulated accident (probability, amounts of the released radionuclides, etc.) and the reference reactor site (meteorology, composite population, land usage), CRAC was used to calculate the atmospheric dispersion and ground deposition of the released radionuclides (Gaussian plume submodel) and the health effects (dosimetric and dose response submodels) and costs (land interdiction and decontamination submodel) resulting from their release. The Gaussian plume model used in CRAC either did not treat or treated simplistically a number of meteorological phenomena. Simplified models were used to treat plume rise, inversion layers, and rainstorms, while wind shear, wind direction, and correlations between wind fields and population distributions were not treated at all. Some of the effects of all of these phenomena on predictions of accident consequences as calculated using CRAC have been or are being investigated. The results of these studies are summarized

  5. Investigation of Deposit Formation Mechanisms for Engine In-cylinder Combustion and Exhaust Systems Using Quantitative Analysis and Sustainability Study

    Science.gov (United States)

    Ye, Z.; Meng, Q.; Mohamadian, H. P.; Wang, J. T.; Chen, L.; Zhu, L.

    2007-06-01

    The formation of SI engine combustion deposits is a complex phenomenon which depends on various factors of fuel, oil, additives, and engine. The goal of this study is to examine the effects of operating conditions, gasoline, lubricating oil, and additives on deposit formation. Both an experimental investigation and theoretical analysis are conducted on a single cylinder engine. As a result, the impact of deposits on engine performance and exhaust emissions (HC, NO x ) has been indicated. Using samples from a cylinder head and exhaust pipe as well as switching gases via the dual-gas method (N2, O2), the deposit formation mechanism is thoroughly investigated via the thermogravity analysis approach, where the roles of organic, inorganic, and volatile components of fuel, additives, and oil on deposit formation are identified from thermogravity curves. Sustainable feedback control design is then proposed for potential emission control and performance optimization

  6. An investigation of the healthy migrant hypothesis: Pre-emigration characteristics of those in the British 1946 birth cohort study.

    Science.gov (United States)

    Fuller-Thomson, Esme; Brennenstuhl, Sarah; Cooper, Rachel; Kuh, Diana

    2016-03-16

    The finding that migrants to high-income countries have lower rates of morbidity and mortality than non-migrants, controlling for socioeconomic position, is often attributed to the "healthy migrant" hypothesis, which suggests that only the healthiest individuals choose to migrate. This prospective study investigates the healthy migrant hypothesis in a cohort of British emigrants using pre-migration health indicators. We also investigate how early-life health characteristics relate to age at emigration and whether or not the emigrant returned home. Data are from the Medical Research Council National Survey of Health and Development, a nationally representative cohort study of people born in England, Scotland or Wales in March 1946. Childhood socio-economic position, health and cognitive ability were compared between 4,378 non-emigrants and 984 emigrants. Of the emigrants, 427 emigrated before age 20 and 557 after that age; 602 emigrants remained abroad and 382 returned home. Emigrants had better childhood health (especially greater height), higher childhood socio-economic position and better childhood cognitive ability at age 8 than non-emigrants. Return emigrants were very similar to emigrants who remained abroad. We found support for the healthy migrant hypothesis in a cohort of British emigrants. Our findings improve an understanding of how health is distributed within and across nations.

  7. Geological mapping of investigation trench OL-TK18 at the Olkiluoto study site, Eurajoki, SW Finland

    Energy Technology Data Exchange (ETDEWEB)

    Engstroem, J. [GTK Geological Survey of Finland, Espoo (Finland)

    2012-04-15

    Survey of Finland at the Olkiluoto study site, Eurajoki, as part of Posiva Oy's site investigation programme for the development of an underground repository for nuclear waste. The E-W striking, ca. 55 m long trench is located in the central part of the Olkiluoto Island adjacent to investigation trenches OL-TK12 and OL-TK4. The trench was cleaned with a pressure washer and pressurized air. The rock types were determined macroscopically. The rock types in investigation trench OL-TK18 is of heterogeneous character, with a large variation in their composition. The rocks vary from tonalitic-granodioritic gneiss to diatexitic gneiss, with portions of K-feldspar porphyritic gneiss. Inclusions of mica gneiss and a well-preserved schollen migmatite is encountered. The trench ends in a feldspar-rich pegmatoid. The most dominant tectonic feature is D{sub 4} ductile deformation domain and associated S{sub 4} foliation. This domain and hence the S{sub 4} foliation is striking NE-SW with a moderate dip towards SE. Both ends of the trench are dominated by the earlier deformation phase, showing S{sub 3} foliation striking ENE-WSW and roughly dipping towards the S. The S{sub 3} foliation is associated with small-scaled granitic leucosome veining, while the S{sub 4} foliation have a schistose character and it is more sheared. D{sub 4} ductile deformation domain is also characterised by a sheared blastomylonitic rock having growth of roundish feldspar porphyroblasts and BTschlierens indicating high alteration of the protolith. During the fracture mapping, all fractures intersecting the central thread were investigated and a total of 117 fractures were recorded. The average fracture frequency of the trench is 2.11 fractures/m. On the basis of fracture orientations one main set can be distinguished striking NE-SW (foliation parallel) with a moderate dip towards the SE. The median fracture trace length is 1.6 m and over half of the fractures exceed 1.5 m trace length, the longest

  8. Planning for investigation and evaluation of potential repository sites in Sweden

    International Nuclear Information System (INIS)

    Almen, K.E.; Stroem, A.

    1998-01-01

    The present stage of siting of the Swedish Deep Repository for spent nuclear fuel involves general siting studies on national and regional scales and feasibility studies on a municipal scale. Based on these studies, two areas will be selected for surface-based site investigations. The geoscientific site information will be used in the site evaluation process, in which performance and safety assessments and design studies are the major activities, in combination with geoscientific characterization. The safety report and EIA document from the site investigation stage will be the most important documents in the application for the siting permit and the permit to construct the deep repository. Detailed characterization will then verify the suitability of the selected site. The programme for geoscientific site investigations is based on experience from more than 20 years of field studies in several SKB projects, such as the Study Site Investigations , the Stripa Project, and the Aespoe Hard Rock Laboratory. The strategies and methodologies developed, implemented and verified within the Aespoe HRL are a very important source of information and know-how for the development of the site investigation programme. The investigations will produce geoscientific models that include all information needed to analyze the long-term safety of a deep repository located in and adapted to the geological conditions of the rock. The type of geoscientific information needed for performance and safety assessment, layout and design, environmental studies and for fundamental geoscientific understanding has been specified and compiled in a 'parameter' report. The general strategy is that performance assessment, layout and design studies will be conducted in parallel with the geoscientific investigations. Information will be transferred at logical occasions, when decisions have to be taken and when feedback is desirable for new investigation steps. The role of the geoscientific evaluation is to

  9. A case study investigation of practices and beliefs of teachers at a STEM-focused elementary school

    Science.gov (United States)

    Martin, Billy J.

    Proponents of STEM education have highlighted the need for increasing STEM skills among students. To address this need, there have been recommendations to create new STEM-focused schools, a majority of which are to be STEM-focused elementary and middle schools. However, STEM school research remains focused on outcomes at the secondary and postsecondary level, with little attention being given to knowing more about the role that elementary education plays in STEM outcomes. Case study design was used to investigate teachers at one STEM-focused elementary school to identify the practices and beliefs reported as important in STEM teaching and learning. Using survey and in-depth interviews, it was found that designation as a STEM-focused school promotes the use of more inquiry-oriented teaching practices and facilitates the use of strategies for developing confidence and competence in STEM among staff and students. The information uncovered in this study could provide leaders of any organization desiring to become a STEM-focused institution information about specific beliefs and practices that have the greatest potential to support changes in teaching.

  10. Investigating the relationship between outsourcing and performance based on Balanced Score Card (Case study Ilam Post Office

    Directory of Open Access Journals (Sweden)

    Karam Khalili

    2014-01-01

    Full Text Available Today, outsourcing can play a crucial role in satisfying customers and meeting their requirements; therefore post office has devoted some of its services and supports for improving the performance, reducing the expenses, and modifying the organizational structure. The main purpose of this study is to investigate the relationship between outsourcing and the performance based on Balanced Score Card (Ilam Post Office in 2013. This study was a descriptive-survey and it utilized a questionnaire for collecting data. SPSS software was used to analyze the data. Useable data were gathered from 18 managers and assistants. T-student and correlation method was used for data analysis. The results showed that there are a strong and positive relationship between outsourcing post office activities and performance management in three aspects of financial, customers and internal processes; however there was a positive and weak relationship between the aspect of learning and outsourcing.

  11. An investigation of somatosensory profiles in work related upper limb disorders: a case-control observational study protocol.

    LENUS (Irish Health Repository)

    Moloney, Niamh

    2010-01-01

    BACKGROUND: Work related upper limb disorders constitute 45% of all occupational diseases and are a significant public health problem. A subgroup, non specific arm pain (NSAP), remains elusive in terms of understanding its pathophysiological mechanisms with its diagnosis based on the absence of specific clinical findings. One commonly proposed theory is that a neural tissue disorder is the primary dysfunction in NSAP and findings from previous studies lend some support to this theory. However, it is not clear if changes identified are simply a consequence of ongoing pain rather than due to specific neural changes. The presence of neuropathic pain has been investigated in several other musculoskeletal conditions but currently, there is no specific diagnostic tool or gold standard which permits an unequivocal diagnosis of neuropathic pain. The purpose of this study is to further describe the somatosensory profiles in patients with NSAP and to compare these profiles to a group of patients with MRI confirmed cervical radiculopathy who have been previously classified as having neuropathic pain. METHODS\\/DESIGN: Three groups of participants will be investigated: Groups 1 and 2 will be office workers with either NSAP or cervical radiculopathy and Group 3 will be a control group of non office workers without upper limb pain. Participants will undergo a clinical assessment, pain questionnaires (LANSS, Short Form McGill, DASH and TSK) and quantitative sensory testing comprising thermal detection and pain thresholds, vibration thresholds and pressure pain thresholds. DISCUSSION: The spectrum of clinically suspected neuropathic pain ranges from more obvious conditions such as trigeminal neuralgia to those with vague signs of nerve disorder such as NSAP. A thorough description of the somatosensory profiles of NSAP patients and a comparison with a more defined group of patients with evidence of neuropathic pain will help in the understanding of underlying neurophysiology in

  12. Magnetic resonance imaging investigation of the bone conduction implant – a pilot study at 1.5 Tesla

    Science.gov (United States)

    Jansson, Karl-Johan Fredén; Håkansson, Bo; Reinfeldt, Sabine; Rigato, Cristina; Eeg-Olofsson, Måns

    2015-01-01

    Purpose The objective of this pilot study was to investigate if an active bone conduction implant (BCI) used in an ongoing clinical study withstands magnetic resonance imaging (MRI) of 1.5 Tesla. In particular, the MRI effects on maximum power output (MPO), total harmonic distortion (THD), and demagnetization were investigated. Implant activation and image artifacts were also evaluated. Methods and materials One implant was placed on the head of a test person at the position corresponding to the normal position of an implanted BCI and applied with a static pressure using a bandage and scanned in a 1.5 Tesla MRI camera. Scanning was performed both with and without the implant, in three orthogonal planes, and for one spin-echo and one gradient-echo pulse sequence. Implant functionality was verified in-between the scans using an audio processor programmed to generate a sequence of tones when attached to the implant. Objective verification was also carried out by measuring MPO and THD on a skull simulator as well as retention force, before and after MRI. Results It was found that the exposure of 1.5 Tesla MRI only had a minor effect on the MPO, ie, it decreased over all frequencies with an average of 1.1±2.1 dB. The THD remained unchanged above 300 Hz and was increased only at lower frequencies. The retention magnet was demagnetized by 5%. The maximum image artifacts reached a distance of 9 and 10 cm from the implant in the coronal plane for the spin-echo and the gradient-echo sequence, respectively. The test person reported no MRI induced sound from the implant. Conclusion This pilot study indicates that the present BCI may withstand 1.5 Tesla MRI with only minor effects on its performance. No MRI induced sound was reported, but the head image was highly distorted near the implant. PMID:26604836

  13. An investigation of somatosensory profiles in work related upper limb disorders: a case-control observational study protocol

    Directory of Open Access Journals (Sweden)

    Hall Toby

    2010-01-01

    Full Text Available Abstract Background Work related upper limb disorders constitute 45% of all occupational diseases and are a significant public health problem. A subgroup, non specific arm pain (NSAP, remains elusive in terms of understanding its pathophysiological mechanisms with its diagnosis based on the absence of specific clinical findings. One commonly proposed theory is that a neural tissue disorder is the primary dysfunction in NSAP and findings from previous studies lend some support to this theory. However, it is not clear if changes identified are simply a consequence of ongoing pain rather than due to specific neural changes. The presence of neuropathic pain has been investigated in several other musculoskeletal conditions but currently, there is no specific diagnostic tool or gold standard which permits an unequivocal diagnosis of neuropathic pain. The purpose of this study is to further describe the somatosensory profiles in patients with NSAP and to compare these profiles to a group of patients with MRI confirmed cervical radiculopathy who have been previously classified as having neuropathic pain. Methods/Design Three groups of participants will be investigated: Groups 1 and 2 will be office workers with either NSAP or cervical radiculopathy and Group 3 will be a control group of non office workers without upper limb pain. Participants will undergo a clinical assessment, pain questionnaires (LANSS, Short Form McGill, DASH and TSK and quantitative sensory testing comprising thermal detection and pain thresholds, vibration thresholds and pressure pain thresholds. Discussion The spectrum of clinically suspected neuropathic pain ranges from more obvious conditions such as trigeminal neuralgia to those with vague signs of nerve disorder such as NSAP. A thorough description of the somatosensory profiles of NSAP patients and a comparison with a more defined group of patients with evidence of neuropathic pain will help in the understanding of underlying

  14. Investigating the neurodevelopmental mediators of aggression in children with a history of child maltreatment:An exploratory field study.

    Science.gov (United States)

    Dileo, J F; Brewer, W; Northam, E; Yucel, M; Anderson, V

    2017-08-01

    Maltreatment of children is a chronic community problem that increases the risk of future aggression. Despite several decades of research highlighting this relationship, few studies have explored the potential neuropsychological deficits that are likely to mediate it. This exploratory study aimed to examine how child maltreatment may be associated with aggression via impairment in the developing prefrontal-limbic-autonomic pathways that are implicated in neuropsychological models of aggression. Furthermore, it aimed to investigate the relationship between child maltreatment and both reactive and proactive aggression subtypes. To investigate this non-invasively in an at-risk population, children with a documented protective care history (n = 20) and a community control group (n = 30), aged between 6 and 12 years, were compared on measures of cardiovascular functioning, affect regulation and cognitive functioning aligned with this neuropsychological model. Whilst no group differences were found on cardiovascular functioning (i.e., resting heart rate, heart rate reactivity, heart rate variability), the protective care group performed significantly worse on measures of affect regulation and cognitive functioning (i.e., global intelligence, executive functioning, smell identification and social cognition). The relationship between child maltreatment and aggression was mediated by executive dysfunction and affect dysregulation but not global IQ, social cognition or olfactory identification. The results suggest that interventions targeting aggression in maltreated children will benefit from clinical assessment and psychological strategies that address the executive dysfunction and affect dysregulation that has been associated with this clinical outcome.

  15. Status of volcanic hazard studies for the Nevada Nuclear Waste Storage Investigations. Volume II

    International Nuclear Information System (INIS)

    Crowe, B.M.; Wohletz, K.H.; Vaniman, D.T.; Gladney, E.; Bower, N.

    1986-01-01

    Volcanic hazard investigations during FY 1984 focused on five topics: the emplacement mechanism of shallow basalt intrusions, geochemical trends through time for volcanic fields of the Death Valley-Pancake Range volcanic zone, the possibility of bimodal basalt-rhyolite volcanism, the age and process of enrichment for incompatible elements in young basalts of the Nevada Test Site (NTS) region, and the possibility of hydrovolcanic activity. The stress regime of Yucca Mountain may favor formation of shallow basalt intrusions. However, combined field and drill-hole studies suggest shallow basalt intrusions are rare in the geologic record of the southern Great Basin. The geochemical patterns of basaltic volcanism through time in the NTS region provide no evidence for evolution toward a large-volume volcanic field or increases in future rates of volcanism. Existing data are consistent with a declining volcanic system comparable to the late stages of the southern Death Valley volcanic field. The hazards of bimodal volcanism in this area are judged to be low. The source of a 6-Myr pumice discovered in alluvial deposits of Crater Flat has not been found. Geochemical studies show that the enrichment of trace elements in the younger rift basalts must be related to an enrichment of their mantle source rocks. This geochemical enrichment event, which may have been metasomatic alteration, predates the basalts of the silicic episode and is, therefore, not a young event. Studies of crater dimensions of hydrovolcanic landforms indicate that the worst case scenario (exhumation of a repository at Yucca Mountain by hydrovolcanic explosions) is unlikely. Theoretical models of melt-water vapor explosions, particularly the thermal detonation model, suggest hydrovolcanic explosion are possible at Yucca Mountain. 80 refs., 21 figs., 5 tabs

  16. Magnetic and microstructural investigation of pipeline steel

    International Nuclear Information System (INIS)

    Groessinger, R.; Mehmood, N.; Hiram Espina, J.; Keplinger, F.

    2008-01-01

    Full text: Magnetic studies (as e.g. hysteresis loop, minor loops initial susceptibility, Barkhausen noise etc.) on pipeline tubes can be used to detect local errors, scratches, stress centres etc. There exist up to now several papers characterising the stress-state of such steels however not yet a systematic investigation correlating the microstructure with intrinsic magnetic properties of the material. Within this paper three different types of steel, which are generally used for pipelines, will be investigated with respect to their microstructure, their magnetic properties (hysteresis) and their magnetostriction. In order to investigate the effect of texture, one sample was cut parallel to the tube direction (longitudinal), one was cut perpendicular to the tube direction (transversal). The microstructure was investigated using a light microscope. The topological structure was investigated using an AFM, the domain structure was observed by a MFM. From all steels frame shaped samples were made which were used to measure the hysteresis loop in a magnetically closed arrangement. (author)

  17. Investigation of Thermal Comfort Conditions in Higher Education Facilities: A Case Study for Engineering Faculty in Edirne

    Directory of Open Access Journals (Sweden)

    E. Mıhlayanlar

    2017-02-01

    Full Text Available In this study, a higher education institution in Edirne (Trakya University Engineering Faculty is investigated for indoor thermal comfort conditions of the classrooms (indoor temperature, relative humidity, average radiant temperature, “Satisfaction from thermal environment” (PMV and “Dissatisfaction from thermal environment” (PPD. The classrooms in the institution are heated by a central heating system and utilise natural ventilation system. Measurements were taken with the proper devices at the same time of the weekdays during lecture times in winter (heating season in December. The results obtained from measurements are given in graphics and compared with the values given in ASHRAE 55 and ISO 7730 standards.

  18. In Search of Police Investigative Thinking Styles: An Exploratory Study of Detectives in Norway and Singapore

    Science.gov (United States)

    Dean, Geoff; Fahsing, Ivar Andre; Gottschalk, Petter

    2007-01-01

    In this paper, we argue that more research attention needs to be devoted to profile how investigators think when attempting to solve crimes and dismantle terrorist networks. Since 9/11, there is much activity focused on profiling criminals and terrorists but little on the other side of the investigative equation the detectives/investigators…

  19. Students' Performance in Investigative Activity and Their Understanding of Activity Aims

    Science.gov (United States)

    Gomes, Alessandro Damasio Trani; Borges, A. Tarciso; Justi, Rosaria

    2008-01-01

    This study investigates the relationship between the students' understanding of the aims of an investigative activity and their performance when conducting it. One hundred and eighty-one year nine students from a public middle school in Brazil took part in the study. Students working in pairs were asked to investigate two problems using a…

  20. Investigating the Effectiveness of a Study Skills Training Programme

    Science.gov (United States)

    Sikhwari, T. D.; Pillay, J.

    2012-01-01

    Various studies have shown that the school system in South Africa is continually producing learners who are inadequately prepared for higher education studies, particularly schools in disadvantaged environments. The University of Venda (UNIVEN) is situated in an educationally disadvantaged environment. Most of the students who enroll at this…

  1. Study on mixing phenomena in T-pipe junction. Experimental analysis using DNS and investigation of mixing process

    International Nuclear Information System (INIS)

    Igarashi, Minoru; Tanaka, Masaaki; Kimura, Nobuyuki; Kamide, Hideki

    2003-02-01

    In the place where hot and cold fluids are mixed, a time and spatial temperature fluctuation occurs. When this temperature fluctuation amplitude is large, it causes high cycle thermal fatigue in surrounding structure (thermal striping phenomena). Mixing area of high and low temperature fluid exists not only in an atomic power plant but also in a general plant, then, it is significant to investigate this phenomena and also to establish an evaluation rule. In Japan Nuclear Cycle Development Institute, several experiments and the improvement of the analysis methods have been carried out to understand thermal striping phenomena and also to construct an evaluation rule, which can be applied to design. Water Experiment on Fluid Mixing in T-pipe with Long Cycle Fluctuation (WATLON), aiming at examining thermal striping phenomena in a mixing tee, is performed to investigate key factors of mixing phenomena. In this study, in order to investigate the fluid mixing phenomena, temperature and flow velocity distribution were measured by movable thermocouple tree and particle image velocimetry (PIV). And the analysis using a in-house direct numerical simulation (DNS) code, DINUS-3 was performed to understand applicability of the analytical method in mixing tee. The temperature and velocity fields obtained from the DINUS-3 were in good agreement with the experimental results. And the prominent frequency of temperature fluctuation was also in good agreement. The DINUS-3 calculation simulated vortex structure in the wake region behind the branch pipe jet. The results of analysis showed that a Karman vortex generated in the wake region behind the branch pipe jet influenced the temperature fluctuation behavior in the mixing tee. And the analytical results revealed that the vortex generated in the wake region behind the branch pipe jet showed the 3-dimensional behavior. (author)

  2. Investigating tangible and mental resources as predictors of perceived household food insecurity during pregnancy among women in a South African birth cohort study.

    Science.gov (United States)

    Pellowski, Jennifer A; Barnett, Whitney; Kuo, Caroline C; Koen, Nastassja; Zar, Heather J; Stein, Dan J

    2017-08-01

    Food insecurity during pregnancy is concerning given the increased nutritional needs of the mother for proper fetal development. However, research is lacking within the South African context to investigate the association of economic and psychosocial factors and food insecurity among pregnant women, using comprehensive, conceptually driven models. This study applies the Network-Individual-Resource (NIR) Model to investigate individual, intimate dyadic, and family level predictors of perceived household food insecurity for pregnant women. 826 pregnant women enrolled in the Drakenstein Child Health Study (DCHS), a birth cohort in two communities in a peri-urban area of South Africa. Hierarchical logistic regressions were used to investigate the impact of household/family, intimate dyads, and individual tangible and mental resources on perceived household food insecurity during the critical period of pregnancy. Perceived household food insecurity was assessed through an adapted version of the USDA Household Food Security Scale - Short Form. Among 826 pregnant women in South Africa, individual-level tangible resources (e.g. income, social assistance, HIV status) and mental resources (e. g. depression, childhood trauma) predicted perceived household food insecurity and these predictors differed by community. Intimate dyadic and family level resources did not predict household food insecurity. Our findings of the economic and psychosocial predictors of perceived household food insecurity among pregnant women in South Africa, mirror findings in general populations. This study provides support for the extension of the NIR model to perceived household food insecurity, particularly regarding individual-level mental and tangible resources, as well as the impact of community-level factors. Future research should investigate the extent to which resource sharing occurs within networks. Copyright © 2017 Elsevier Ltd. All rights reserved.

  3. Forsmark site investigation. Programme for further investigations of geosphere and biosphere

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-01-01

    Since the beginning of 2002, SKB (the Swedish Nuclear Fuel and Waste Management Co) has been conducting a site investigation in Forsmark in the municipality of Oesthammar for siting of the deep repository for spent nuclear fuel. An equivalent investigation is also being conducted at Simpevarp and Laxemar in Oskarshamn Municipality. SKB's goal is to submit an application under the Environmental Code and the Nuclear Activities Act for siting of the deep repository at one of these sites by the end of 2008/beginning of 2009. When the application is submitted, everything of importance for the deep repository's safety, constructability and environmental impact shall have been investigated and analyzed. The investigations shall also provide data as a basis for selecting a site and configuring the facility to suit conditions on the site.SKB submitted a programme for the initial site investigation in Forsmark at the end of 2001. The investigations described there have now been completed. This report describes the programme that has now been prepared for the remainder of the site investigation. The points of departure are the general goals for the Deep Repository Project during the site investigation phase, the data needed for evaluation of the site, plus experience and results from the work to date. The programme has been prepared with the support of investigation data as of August 2004. The investigations described here will, as before, be conducted with great consideration given to residents, property owners and natural and cultural values so that they are not unnecessarily exposed to impact or disturbances. Just as before, the programme will be continuously adapted to the knowledge that is gradually accumulated on the site. All important changes will be reported to the authorities and other concerned parties. The investigations that have been conducted (as of August 2004) and their results can be summarized in the following points: The surface characterization

  4. Forsmark site investigation. Programme for further investigations of geosphere and biosphere

    International Nuclear Information System (INIS)

    2005-01-01

    Since the beginning of 2002, SKB (the Swedish Nuclear Fuel and Waste Management Co) has been conducting a site investigation in Forsmark in the municipality of Oesthammar for siting of the deep repository for spent nuclear fuel. An equivalent investigation is also being conducted at Simpevarp and Laxemar in Oskarshamn Municipality. SKB's goal is to submit an application under the Environmental Code and the Nuclear Activities Act for siting of the deep repository at one of these sites by the end of 2008/beginning of 2009. When the application is submitted, everything of importance for the deep repository's safety, constructability and environmental impact shall have been investigated and analyzed. The investigations shall also provide data as a basis for selecting a site and configuring the facility to suit conditions on the site.SKB submitted a programme for the initial site investigation in Forsmark at the end of 2001. The investigations described there have now been completed. This report describes the programme that has now been prepared for the remainder of the site investigation. The points of departure are the general goals for the Deep Repository Project during the site investigation phase, the data needed for evaluation of the site, plus experience and results from the work to date. The programme has been prepared with the support of investigation data as of August 2004. The investigations described here will, as before, be conducted with great consideration given to residents, property owners and natural and cultural values so that they are not unnecessarily exposed to impact or disturbances. Just as before, the programme will be continuously adapted to the knowledge that is gradually accumulated on the site. All important changes will be reported to the authorities and other concerned parties. The investigations that have been conducted (as of August 2004) and their results can be summarized in the following points: The surface characterization of the

  5. Investigation on ionic states of 1,2-Dipalmitoyl-sn-glycero-3-phosphorylcholine (DPPC) using organic laser dyes: A FRET study

    Energy Technology Data Exchange (ETDEWEB)

    Roy, Arpan Datta; Saha, Jaba; Dey, D.; Bhattacharjee, D.; Hussain, Syed Arshad, E-mail: sa_h153@hotmail.com

    2017-05-15

    Fluorescence Resonance Energy Transfer (FRET) between two organic dyes Fluorescein and Rhodamine 6G were successfully investigated in aqueous solution in presence and absence of 1,2-Dipalmitoyl-sn-glycero-3-phosphorylcholine (DPPC) at different pH. Spectroscopic studies suggest that both the dyes were present mainly as monomer in solution. FRET occurred from Fluorescein to Rhodamine 6G in solutions. Energy transfer efficiency increases in presence of DPPC and the maximum efficiency was 59.3% when the concentration of DPPC was 1.4×10{sup −4} M at ambient condition. pH plays a crucial role in this investigation as the energy transfer efficiency was found to change in presence of DPPC at different pH. It has been demonstrated that with proper calibration it is possible to use the present system under investigation to realize various ionic states of DPPC by observing the change in FRET efficiency between these two dyes. - Graphical abstract: Electrostatic interaction between anionic Flu and cationic R6G molecules in presence and absence of DPPC at different pH. Here pH of DPPC was changed, not the pH of individual dyes.

  6. Diamond Fire: Serious Accident Investigation Report

    Science.gov (United States)

    John Waconda; Ivan Pupulidy; Leonard Diaz; Robin Broyles; Roberta Junge; James Saveland

    2012-01-01

    This incident is effectively two studies. The first study, and the reason the Serious Accident Investigation Team was assembled, was due to a fatality, which the autopsy later determined to have been caused by a heart attack. The team was not aware of the cause of death for over 4 weeks after the incident occurred. However, the observed and reported cases of heat...

  7. Investigation of Barriers and Factors Affecting the Reverse Logistics of Waste Management Practice: A Case Study in Thailand

    Directory of Open Access Journals (Sweden)

    Sumalee Pumpinyo

    2014-10-01

    Full Text Available Economic growth in developing countries accelerated waste generation, and Thailand also is experiencing issues related to increased waste generation and improper waste management. The country’s domestic waste utilization is only 20%–26%. Efficient waste management and increased quantity of waste utilization is possible only by overcoming problems and constraints in reverse logistics (RL systems in Thailand. To address these issues and constraints, this study aims to focus the investigation on the current practices in the RL systems. The study was conducted in Bangkok and its vicinity. An integrated approach of qualitative and quantitative methods was employed to investigate the systems’ and stakeholders’ characteristics and to explore the factors influencing and constraining RL practices. Data were gathered through: (1 existing literature and in-depth interviews of key stakeholders involved in RL; and (2 a questionnaire survey of 98 managers of separation centers (SCs probing their practices and studying the factors influencing those practices. The findings showed that RL systems can be separated into three levels, i.e., downstream, middle stream and upstream. SCs are key stakeholders in RL of waste management, and they collect waste from downstream, manage waste in a systematic way and send it upstream. The factors influencing and the barriers in the flow of recyclable waste are related to environmental, economic and social aspects. The analysis shows that waste managed by a cooperative-like franchise of SCs perceived that their practices were more efficient than those of a non-franchise practices. Additionally, these SCs have more bargaining power with waste buyers and sellers to set prices in the RL system. The constraints in RL practice are related to finance, market, labor, management/technology and legal issues.

  8. Effects of maternal chlorpyrifos diet on social investigation and brain neuroendocrine markers in the offspring - a mouse study.

    Science.gov (United States)

    Venerosi, Aldina; Tait, Sabrina; Stecca, Laura; Chiarotti, Flavia; De Felice, Alessia; Cometa, Maria Francesca; Volpe, Maria Teresa; Calamandrei, Gemma; Ricceri, Laura

    2015-04-02

    Chlorpyrifos (CPF) is one of the most widely used organophosphate pesticides worldwide. Epidemiological studies on pregnant women and their children suggest a link between in utero CPF exposure and delay in psychomotor and cognitive maturation. A large number of studies in animal models have shown adverse effects of CPF on developing brain and more recently on endocrine targets. Our aim was to determine if developmental exposure to CPF affects social responsiveness and associated molecular neuroendocrine markers at adulthood. Pregnant CD1 outbred mice were fed from gestational day 15 to lactation day 14 with either a CPF-added (equivalent to 6 mg/kg/bw/day during pregnancy) or a standard diet. We then assessed in the offspring the long-term effects of CPF exposure on locomotion, social recognition performances and gene expression levels of selected neurondocrine markers in amygdala and hypothalamus. No sign of CPF systemic toxicity was detected. CPF induced behavioral alterations in adult offspring of both sexes: CPF-exposed males displayed enhanced investigative response to unfamiliar social stimuli, whereas CPF-exposed females showed a delayed onset of social investigation and lack of reaction to social novelty. In parallel, molecular effects of CPF were sex dimorphic: in males CPF increased expression of estrogen receptor beta in hypothalamus and decreased oxytocin expression in amygdala; CPF increased vasopressin 1a receptor expression in amygdala in both sexes. These data indicate that developmental CPF affects mouse social behavior and interferes with development of sex-dimorphic neuroendocrine pathways with potential disruptive effects on neuroendocrine axes homeostasis. The route of exposure selected in our study corresponds to relevant human exposure scenarios, our data thus supports the view that neuroendocrine effects, especially in susceptible time windows, should deserve more attention in risk assessment of OP insecticides.

  9. A focus group study of enteric disease case investigation: successful techniques utilized and barriers experienced from the perspective of expert disease investigators

    OpenAIRE

    Ing, Stanley; Lee, Christina; Middleton, Dean; Savage, Rachel D; Moore, Stephen; Sider, Doug

    2014-01-01

    Background In Ontario, Canada, enteric case investigators perform a number of functions when conducting telephone interviews including providing health education, collecting data for regulatory purposes ultimately to prevent further illness, enforcement, illness source attribution and outbreak detection. Information collected must be of high quality as it may be used to inform decisions about public health actions that could have significant consequences such as excluding a person from work, ...

  10. From acute to persistent low back pain: a longitudinal investigation of somatosensory changes using quantitative sensory testing-an exploratory study.

    Science.gov (United States)

    Marcuzzi, Anna; Wrigley, Paul J; Dean, Catherine M; Graham, Petra L; Hush, Julia M

    2018-03-01

    Chronic low back pain (LBP) is commonly associated with generalised pain hypersensitivity. It is suggested that such somatosensory alterations are important determinants for the transition to persistent pain from an acute episode of LBP. Although cross-sectional research investigating somatosensory function in the acute stage is developing, no longitudinal studies designed to evaluate temporal changes have been published. This exploratory study aimed to investigate the temporal development of somatosensory changes from the acute stage of LBP to up to 4 months from onset. Twenty-five people with acute LBP (testing with the assessor blinded to group allocation, and again at 2 and 4 months. Psychological variables were concurrently assessed. People with acute LBP were classified based on their average pain severity over the previous week at 4 months as recovered (≤1/10 numeric rating scale) or persistent (≥2/10 numeric rating scale) LBP. In the persistent LBP group, (1) there was a significant decrease in pressure pain threshold between 2 and 4 months ( P psychological variables were significantly higher in those with persistent LBP compared with the recovered LBP group at all time points ( P importance of concurrent evaluation of psychological contributors in acute LBP.

  11. Effect of Calcifications on Breast Ultrasound Shear Wave Elastography: An Investigational Study.

    Science.gov (United States)

    Gregory, Adriana; Mehrmohammadi, Mohammad; Denis, Max; Bayat, Mahdi; Stan, Daniela L; Fatemi, Mostafa; Alizad, Azra

    2015-01-01

    To investigate the effects of macrocalcifications and clustered microcalcifications associated with benign breast masses on shear wave elastography (SWE). SuperSonic Imagine (SSI) and comb-push ultrasound shear elastography (CUSE) were performed on three sets of phantoms to investigate how calcifications of different sizes and distributions influence measured elasticity. To demonstrate the effect in vivo, three female patients with benign breast masses associated with mammographically-identified calcifications were evaluated by CUSE. Apparent maximum elasticity (Emax) estimates resulting from individual macrocalcifications (with diameters of 2mm, 3mm, 5mm, 6mm, 9mm, 11mm, and 15mm) showed values over 50 kPa for all cases, which represents more than 100% increase over background (~21kPa). We considered a 2cm-diameter circular region of interest for all phantom experiments. Mean elasticity (Emean) values varied from 26 kPa to 73 kPa, depending on the macrocalcification size. Highly dense clusters of microcalcifications showed higher Emax values than clusters of microcalcification with low concentrations, but the difference in Emean values was not significant. Our results demonstrate that the presence of large isolated macrocalcifications and highly concentrated clusters of microcalcifications can introduce areas with apparent high elasticity in SWE. Considering that benign breast masses normally have significantly lower elasticity values than malignant tumors, such areas with high elasticity appearing due to presence of calcification in benign breast masses may lead to misdiagnosis.

  12. Effect of Calcifications on Breast Ultrasound Shear Wave Elastography: An Investigational Study.

    Directory of Open Access Journals (Sweden)

    Adriana Gregory

    Full Text Available To investigate the effects of macrocalcifications and clustered microcalcifications associated with benign breast masses on shear wave elastography (SWE.SuperSonic Imagine (SSI and comb-push ultrasound shear elastography (CUSE were performed on three sets of phantoms to investigate how calcifications of different sizes and distributions influence measured elasticity. To demonstrate the effect in vivo, three female patients with benign breast masses associated with mammographically-identified calcifications were evaluated by CUSE.Apparent maximum elasticity (Emax estimates resulting from individual macrocalcifications (with diameters of 2mm, 3mm, 5mm, 6mm, 9mm, 11mm, and 15mm showed values over 50 kPa for all cases, which represents more than 100% increase over background (~21kPa. We considered a 2cm-diameter circular region of interest for all phantom experiments. Mean elasticity (Emean values varied from 26 kPa to 73 kPa, depending on the macrocalcification size. Highly dense clusters of microcalcifications showed higher Emax values than clusters of microcalcification with low concentrations, but the difference in Emean values was not significant.Our results demonstrate that the presence of large isolated macrocalcifications and highly concentrated clusters of microcalcifications can introduce areas with apparent high elasticity in SWE. Considering that benign breast masses normally have significantly lower elasticity values than malignant tumors, such areas with high elasticity appearing due to presence of calcification in benign breast masses may lead to misdiagnosis.

  13. Investigation of the molecular level interactions between mucins and food proteins: Spectroscopic, tribological and rheological studies

    DEFF Research Database (Denmark)

    Celebioglu, Hilal Yilmaz

    The thesis investigated the structure and molecular-level interaction of β-lactoglobulin (BLG) and mucins, representing major components of the dairy products and saliva/digestion systems, respectively. Mucins are long glycoprotein molecules responsible for the gel nature of the mucous layer covers...... epithelial surfaces throughout the body. A literature review of the interactions of different mucin types and saliva mucins with several food proteins and food protein emulsions, as well as their functional properties related to the food oral processing is presented at the first chapter of the thesis (Paper...... V). Most of the studies suggest an electrostatic attraction between positively charged food proteins with negatively charged moieties of mucins (mainly on glycosylated region of mucins). The structural changes occurring during the interaction between BLG, the major whey protein, and bovine...

  14. Early Results from the Odyssey THEMIS Investigation

    Science.gov (United States)

    Christensen, Philip R.; Bandfield, Joshua L.; Bell, James F., III; Hamilton, Victoria E.; Ivanov, Anton; Jakosky, Bruce M.; Kieffer, Hugh H.; Lane, Melissa D.; Malin, Michael C.; McConnochie, Timothy

    2003-01-01

    The Thermal Emission Imaging System (THEMIS) began studying the surface and atmosphere of Mars in February, 2002 using thermal infrared (IR) multi-spectral imaging between 6.5 and 15 m, and visible/near-IR images from 450 to 850 nm. The infrared observations continue a long series of spacecraft observations of Mars, including the Mariner 6/7 Infrared Spectrometer, the Mariner 9 Infrared Interferometer Spectrometer (IRIS), the Viking Infrared Thermal Mapper (IRTM) investigations, the Phobos Termoscan, and the Mars Global Surveyor Thermal Emission Spectrometer (MGS TES). The THEMIS investigation's specific objectives are to: (1) determine the mineralogy of localized deposits associated with hydrothermal or sub-aqueous environments, and to identify future landing sites likely to represent these environments; (2) search for thermal anomalies associated with active sub-surface hydrothermal systems; (3) study small-scale geologic processes and landing site characteristics using morphologic and thermophysical properties; (4) investigate polar cap processes at all seasons; and (5) provide a high spatial resolution link to the global hyperspectral mineral mapping from the TES investigation. THEMIS provides substantially higher spatial resolution IR multi-spectral images to complement TES hyperspectral (143-band) global mapping, and regional visible imaging at scales intermediate between the Viking and MGS cameras.

  15. LSS, a problem solving skill for graduates and SMEs: Case Study of investigation in a UK Business School curriculum

    OpenAIRE

    Shokri, Alireza; Nabhani, Farhad

    2015-01-01

    Purpose - This research aims to investigate the feasibility of a systematic Lean Six Sigma (LSS) education through the curriculum of business schools to respond to the existing gap between the graduate’s expectation of employability and skill requirements by the Small and Medium Sized Enterprises (SMEs).\\ud \\ud Design/approach/methodology - One UK business school has been used as a case study to conduct an extensive module and programme review followed by a semi-structured interview with the ...

  16. Investigation of the Potential Market and Estimation of WTP for Insurance of Pistachio Tree Trunk (Case Study Rafsanjan-Iran)

    OpenAIRE

    Baniasadi, Mostafa; Yazdani, Saeed; Salami, Habib Allah

    2013-01-01

    Capacity of garden productions in Iran is such that is accounted as a country that produces thirteen garden products in the world but despite excellent condition in Iran for producing garden products, natural disasters damage production of fruits in the country therefore farmers incur a loss. Pistachio tree has been in danger of destruction and dryness. Thus, in order to reduce loss incurred on trees, it is necessary to insure the tree. This study is aimed to investigate ...

  17. Investigation of Inquiry-based Science Pedagogy among Middle Level Science Teachers: A Qualitative Study

    Science.gov (United States)

    Weiland, Sunny Minelli

    This study implemented a qualitative approach to examine the phenomenon of "inquiry-based science pedagogy or inquiry instruction" as it has been experienced by individuals. Data was collected through online open-ended surveys, focus groups, and teacher reported self-reflections to answer the research questions: 1) How do middle level science teachers conceptualize "inquiry-based instruction?" 2) What are preferred instructional strategies for implementation in middle level science classrooms? And 3) How do middle level science teachers perceive the connection between science instruction and student learning? The participants within this research study represent 33 percent of teachers in grades 5 through 9 within six school districts in northeastern Pennsylvania. Of the 12 consent forms originally obtained, 10 teachers completed all three phases of the data collection, including the online survey, participation in focus groups, and teacher self-reflection. 60 percent of the participants taught only science, and 40 percent taught all content areas. Of the ten participants, 50 percent were certified teachers of science and 50 percent were certified as teachers of elementary education. 70 percent of the research participants reflected having obtained a master's, with 60 percent of these degrees being received in areas of education, and 10 percent in the area of science. The research participants have a total of 85 collective years of experience as professional educators, with the average years of experience being 8.5 years. Analysis of data revealed three themes related to research question #1) How do middle-level science teachers conceptualize inquiry-based instruction? and sub-question #1) How do middle-level science teachers characterize effective instruction? The themes that capture the essence of teachers' formulation of inquiry-based instruction that emerged in this study were student centered, problem solving, and hands-on . Analysis of data revealed one theme

  18. A Study Related to the Investigation of Multiple Intelligence Profiles of Gifted and Talented Children across Turkey

    Directory of Open Access Journals (Sweden)

    Gamze DOLU

    2014-12-01

    Full Text Available Focusing on the dominant intelligences of individuals from their early ages will be beneficial for them and the society in terms of improving their talents. When this situation is considered for gifted and talented children, we believe that there is a need for detailed analysis for Turkey beginning from the early years of children. Hence, in this study, it is aimed to investigate the multiple intelligence domains of Turkish gifted and talented students studying in science and art centres (SACs across the country via a survey research. This paper presents the results gained from 12 SACs. Those SACs were selected according to the socio-economic development index (SEDI of Turkey as declared by Ministry of Development (MD which considered the country to consist of 6 regions. Two SACs from each of those six regions were included in the study. Thus, the sample consisted of 390 middle school 5th grade students. A Likert type multiple intelligence test which included 80 items related to eight domains of multiple intelligence was utilized as data collection instrument (Demirel, Başbay & Erdem, 2006: 155. Descriptive statistics and non-parametric statistics tests were conducted in order to analyze the study data. The results indicated various differences among multiple intelligence scores of the participants.

  19. Learning How to Be a Research-Minded Teacher: Four Instrumental Music Education Students Investigate Good Music Teaching through Case Study Methodology

    Science.gov (United States)

    Sindberg, Laura K.

    2016-01-01

    Increasing evidence, both in general education and music education, points to the significance of inquiry as a part of teacher preparation. The purpose of this case study was to investigate the ways in which an introductory research project would help preservice music educators understand good "music teaching" and to discover the extent…

  20. Investigation of uranium resources out of Japan. Summary on investigation techniques

    International Nuclear Information System (INIS)

    2001-03-01

    Investigation of uranium resources in Japan was begun on 1954 by inland survey of the Geological Survey Bureau in the Agency of Industrial Science and Technology, Ministry of Industrial Trade and Industry, and then it was inherited to the Atomic Fuel Corporation and the Power Reactor and Nuclear Fuel Development Corporation (PNC). Since 1960s, under expectation of rapid growth of nuclear power generation and increase of uranium demand, as it was elucidated to be impossible to fill to its inland demand in quality and quantity, investigation of uranium resources out of Japan by private companies and its basic survey out of Japan by government were promoted. However, in accompanying with revise of PNC to be Japan Nuclear Cycle Development Institute, withdraw of the ore mining business was determined. According to the determination, as a result of investigation on inheritance of right of mining out of Japan to inland companies, rights in Canada were finished to inherit on November, 2000. Here were described on outlines on investigation, investigative method, and investigative business on uranium resources. (G.K.)

  1. Black swan protection: an experimental investigation

    OpenAIRE

    Morone, Andrea; Ozdemir, Ozlem

    2012-01-01

    This experimental study investigates insurance decisions in low-probability, high-loss risk situations. Results indicate that subjects consider the probability of loss (loss size) when they make buying decisions (paying decisions). Most individuals are risk averse with no specific threshold probability.

  2. Remedial investigation/feasibility study of the Clinch River/Poplar Creek operable unit. Volume 3: Appendixes E and F -- Risk assessment information

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-06-01

    This report presents the findings of an investigation into contamination of the Clinch River and Poplar Creek near the US Department of Energy`s (DOE`s) Oak Ridge Reservation (ORR) in eastern Tennessee. For more than 50 years, various hazardous and radioactive substances have been released to the environment as a result of operations and waste management activities at the ORR. In 1989, the ORR was placed on the National Priorities List (NPL), established and maintained under the federal Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). Under CERCLA, NPL sites must be investigated to determine the nature and extent of contamination at the site, assess the risk to human health and the environment posed by the site, and, if necessary, identify feasible remedial alternatives that could be used to clean the site and reduce risk. To facilitate the overall environmental restoration effort at the ORR, CERCLA activities are being implemented individually as distinct operable units (OUs). This document is the combined Remedial Investigation and Feasibility Study Report for the Clinch River/Poplar Creek OU.

  3. Molecular & Genetic Investigation of Tau in Chronic Traumatic Encephalopathy

    Science.gov (United States)

    2015-10-01

    AWARD NUMBER: W81XWH-14-1-0399 TITLE: Molecular & Genetic Investigation of Tau in Chronic Traumatic Encephalopathy PRINCIPAL INVESTIGATOR: John F...Include area code) October 2015 Annual Report 30 Sep 2014 - 29 Sep 2015 Molecular & Genetic Investigation of Tau in Chronic Traumatic Encephalopathy John... encephalopathy (CTE), but the underlying molecular changes remain unclear. Here, biochemical and genetic studies that deepen our understanding of the

  4. Investigations of food irradiation technology in Japan

    International Nuclear Information System (INIS)

    2009-01-01

    All Nippon Spice Assoc. (ANSA) requested the approval in the Ministry of Health Labour and Welfare (MHLW) of radiation irradiation of their products for sterilization and pesticide in 2000. Problems of food irradiation (FI) which started from this ANSA request have been investigated by concerned Japanese administrations and associations with reference to trends in foreign countries, and of which outline till Aug., 2009 is described in this paper. On ANSA petition, AEC (Atomic Energy Committee) required the investigation of the safety problem in FI as it matched AEC policy and there have been background problems of Japanese people who have been having refusal response to radiation themselves. In 2003, Food Safety Committee (FSC) started, and AEC radiation expert committee investigated the trend and detection methodology of irradiated foods. Next year, FSC approved the irradiation of potato to prevent budding; MHLW began to study the detection methodology; and AEC mentioned to consider the FI problem in the Cabinet meeting and set up its expert committee (2005). MHLW reported the above decision in Councils of food/drug and of food hygiene (2006), published the methodology (thermoluminescence method) and started to monitor spices; and FSC discussed about FI problems with World Health Organization (WHO) experts (2007). During these years, the administrations trusted various investigations like foreign trends, safety and assessment of FI. In 2009, MHLW published results of their trusted investigations, based on which food hygienic and standardization sections began to investigate the problems; and FSC, the toxicity study of alkylcyclobutanone. During the period later than 2007, not only spices but also other foods like dried vegetables, tea, certain farm and marine products have been subject to monitoring (MHLW). Thus, MHLW has taken a leading role in actual approval of irradiated potato and in monitoring of imported foods. (K.T.)

  5. Wildlife health investigations: needs, challenges and recommendations

    Science.gov (United States)

    2013-01-01

    In a fast changing world with growing concerns about biodiversity loss and an increasing number of animal and human diseases emerging from wildlife, the need for effective wildlife health investigations including both surveillance and research is now widely recognized. However, procedures applicable to and knowledge acquired from studies related to domestic animal and human health can be on partly extrapolated to wildlife. This article identifies requirements and challenges inherent in wildlife health investigations, reviews important definitions and novel health investigation methods, and proposes tools and strategies for effective wildlife health surveillance programs. Impediments to wildlife health investigations are largely related to zoological, behavioral and ecological characteristics of wildlife populations and to limited access to investigation materials. These concerns should not be viewed as insurmountable but it is imperative that they are considered in study design, data analysis and result interpretation. It is particularly crucial to remember that health surveillance does not begin in the laboratory but in the fields. In this context, participatory approaches and mutual respect are essential. Furthermore, interdisciplinarity and open minds are necessary because a wide range of tools and knowledge from different fields need to be integrated in wildlife health surveillance and research. The identification of factors contributing to disease emergence requires the comparison of health and ecological data over time and among geographical regions. Finally, there is a need for the development and validation of diagnostic tests for wildlife species and for data on free-ranging population densities. Training of health professionals in wildlife diseases should also be improved. Overall, the article particularly emphasizes five needs of wildlife health investigations: communication and collaboration; use of synergies and triangulation approaches; investments

  6. Study of Government Support System in SMEs: An Empirical Investigation

    Directory of Open Access Journals (Sweden)

    Hussain Bux Marri

    2011-07-01

    Full Text Available The SMEs (Small and Medium Enterprises have created its own place and value universally, no matter how tough global competition is there in international market. This research work was undertaken to assess the increase in importance of SMEs in growing nations such as Pakistan and to highlight the importance of SMEs. This paper is validated through research work undertaken by domestic and worldwide scholars. Research work was carried out in enterprises of Sindh, province of Pakistan, using questionnaire and personal discussions with business owners/entrepreneurs of enterprises. Their response was very positive on parameters which were focused towards taxation policies (Rebate, government technological support, financial support and loan facilities. In addition to this, the results were further investigated and measured through statistical measures such as mean/average, which indicate that majority of enterprises, were not happy with country\\'s administration in terms of support they receive. Whereas, there are noticeable indications that government\\'s assistance to small and medium enterprises is very necessary at every stage. Enterprises which have received assistance from their governments have proved to be successful in developing nations.

  7. Deterioration of flood affected Queensland roads – An investigative study

    Directory of Open Access Journals (Sweden)

    Masuda Sultana

    2016-11-01

    Full Text Available The aim of this paper was to investigate the impact of recent flooding events on the structural and surface condition (such as roughness and rutting of the pavements of the Department of Transport and Main Roads, Queensland, and the Brisbane City Council. The paper also reviewed the major flooding and cyclone events that occurred in the last six years in Queensland. Generally, a rapid increase in deterioration of the structural and surface conditions such as roughness and rutting was observed in pavements after the flood as a result of the inundation. An increasing need for road rehabilitation was also observed after the recent flooding events from 2010 to 2015 in Queensland. Assessing the rapid deterioration of the structural and surface condition of the flood affected pavements is a prerequisite for the accurate prediction of pavement performance, a better decision making process and the management of these roads. Although this paper did not include any model for roughness and rutting, deterioration models for roughness and rutting of flood affected pavements are currently being developed as a part of the future scope of this research. Keywords: Pavement deterioration, Flooding, Structural and surface condition

  8. Building energy performance analysis by an in-house developed dynamic simulation code: An investigation for different case studies

    International Nuclear Information System (INIS)

    Buonomano, Annamaria; Palombo, Adolfo

    2014-01-01

    Highlights: • A new dynamic simulation code for building energy performance analysis is presented. • The thermal behavior of each building element is modeled by a thermal RC network. • The physical models implemented in the code are illustrated. • The code was validated by the BESTEST standard procedure. • We investigate residential buildings, offices and stores in different climates. - Abstract: A novel dynamic simulation model for the building envelope energy performance analysis is presented in this paper. This tool helps the investigation of many new building technologies to increase the system energy efficiency and it can be carried out for scientific research purposes. In addition to the yearly heating and cooling load and energy demand, the obtained output is the dynamic temperature profile of indoor air and surfaces and the dynamic profile of the thermal fluxes through the building elements. The presented simulation model is also validated through the BESTEST standard procedure. Several new case studies are developed for assessing, through the presented code, the energy performance of three different building envelopes with several different weather conditions. In particular, dwelling and commercial buildings are analysed. Light and heavyweight envelopes as well as different glazed surfaces areas have been used for every case study. With the achieved results interesting design and operating guidelines can be obtained. Such data have been also compared vs. those calculated by TRNSYS and EnergyPlus. The detected deviation of the obtained results vs. those of such standard tools are almost always lower than 10%

  9. Investigational study of optical function materials for two-dimensional data processing; Nijigen joho shoriyo hikari kino zairyo ni kansuru chosa kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    The paper investigated/studied `space light modulation materials,` `dynamic hologram/memory materials,` `optical waveguide path materials,` etc. which become key materials in the high speed two dimensional processing. As to electrooptical materials proposed in this investigational study, the external electric field and the electric charges generated make quality of molecules themselves directly change to memory strong/weak signals of light. Therefore, the response velocity becomes less than a millionth of that of the liquid crystal display, and high speed which is needed for realtime moving image processing is anticipated. Hologram includes the phase information in addition to information on light strength. Therefore, it is a large capacity record medium and at the same time a record medium which can read/write two dimensional information as it is. With optical fiber, images cannot be transmitted as they are. Light waveguide path materials are those that accumulate roles of mirror and lens in a sheet of the material and construct a system which is strong in vibration, as optical parts connecting among materials for two dimensional data processing. 273 refs., 107 figs., 17 tabs.

  10. Investigation of the influence of design details on short implant biomechanics using colorimetric photoelastic analysis: a pilot study

    Directory of Open Access Journals (Sweden)

    João César Zielak

    Full Text Available Introduction : The clinical survival of a dental implant is directly related to its biomechanical behavior. Since short implants present lower bone/implant contact area, their design may be more critical to stress distribution to surrounding tissues. Photoelastic analysis is a biomechanical method that uses either simple qualitative results or complex calculations for the acquisition of quantitative data. In order to simplify data acquisition, we performed a pilot study to demonstrate the investigation of biomechanics via correlation of the findings of colorimetric photoelastic analysis (stress transition areas; STAs of design details between two types of short dental implants under axial loads. Methods Implants were embedded in a soft photoelastic resin and axially loaded with 10 and 20 N of force. Implant design features were correlated with the STAs (mm2 of the colored fringes of colorimetric photoelastic analysis. Results Under a 10 N load, the surface area of the implants was directly related to STA, whereas under a 20 N load, the surface area and thread height were inversely related to STA. Conclusion A smaller external thread height seemed to improve the biomechanical performance of the short implants investigated.

  11. Investigation of surface homogeneity of mirrors for the CBM-RICH detector and low-mass di-electron feasibility studies

    International Nuclear Information System (INIS)

    Lebedeva, E; Hoehne, C

    2014-01-01

    The Compressed Baryonic Matter (CBM) experiment at the future FAIR facility will investigate high net-baryon density matter at moderate temperatures in A+A collisions from 4-45 AGeV. One of the key observables of the CBM physics program is electromagnetic radiation as a probe of strongly interacting matter in heavy-ion collisions, carrying undistorted information on its conditions to the detector. This includes detailed investigations of low-mass vector mesons in their di-electron channel. A clean and efficient identification of electrons is required for such measurements. In CBM the electron identification will be performed by a Ring Imaging Cherenkov detector and several layers of Transition Radiation Detectors. The RICH detector will be operated with CO 2 radiator gas, MAPMTs as photodetector and spherical glass mirrors as focusing elements. A high quality of the mirrors in terms of reflectivity and surface homogeneity is required. In the first part of the contribution results on measurements of the mirror surface homogeneity are presented. Results on the feasibility studies of low-mass di-electron measurements with realistic detector response are discussed in the second part of the contribution.

  12. The micrometeorological investigation of heat flux and moisture ...

    African Journals Online (AJOL)

    The diurnal and seasonal variations of heat flux and the moisture content in the soil at a site for the Nigeria Mesoscale Experiment (NIMEX) in the University of Ibadan, Nigeria (7.380 N and 3.930 E), had been investigated. The study also investigated effects of the atmospheric phenomena on magnitudes of the surface layer ...

  13. Verification study on technology for site investigation for geological disposal. Confirmation of the applicability of survey methods through establishing site descriptive models in accordance with stepwise investigation approach

    International Nuclear Information System (INIS)

    Kondo, Hirofumi; Suzuki, Koichi; Hasegawa, Takuma; Hamada, Takaomi; Yoshimura, Kimitaka

    2014-01-01

    The Yokosuka Demonstration and Validation Project, which uses the Yokosuka Central Research Institute of Electric Power Industry (CRIEPI) site, a Neogene sedimentary and coastal environment, has been conducted since the 2006 fiscal year as a cooperative research project between NUMO (Nuclear Waste Management Organization of Japan) and CRIEPI. The objectives of this project were to examine and refine the basic methodology of the investigation and assessment in accordance with the conditions of geological environment at each stage of investigations from the surface (Preliminary Investigation and the first half of Detailed Investigation conducted by NUMO) for high level radioactive waste geological disposal. Within investigation technologies at these early stages, a borehole survey is an important means of directly obtaining various properties of the deep geological environment. On the other hand, surface geophysical prospecting data provide information about the geological and resistivity structures at depth for planning borehole surveys. During the 2006-2009 fiscal years, a series of on-site surveys and tests, including borehole surveys of YDP-1 (depth: 350 m) and YDP-2 (depth: 500 m), were conducted in this test site. Furthermore, seismic surveys (including seismic reflection method) and electromagnetic surveys (including magnetotelluric method) were conducted within the expanded CRIEPI site in the 2010 fiscal year to obtain information about the geological structure, and the resistivity structure reflecting the distribution of the salt water/fresh water boundary, respectively, to a depth of over several hundred meters. The validity of existing survey and testing methods for stepwise investigations (from surface to borehole surveys) for obtaining properties of the geological environment (in various conditions relating to differences in the properties of the Miura and the Hayama Groups at this site) was confirmed through establishing site descriptive models based on

  14. Final report on neutron irradiation at low temperature to investigate plastic instability and at high temperature to study caviation

    DEFF Research Database (Denmark)

    Singh, B.N; Eldrup, Morten Mostgaard; Golubov, D.J.

    2005-01-01

    Effects of neutron irradiation on defect accumulation and physical and mechanical properties of pure iron and F82H and EUROFER 97 ferritic-martensitic steels have been investigated. Tensile specimens were neutron irradiated to a dose level of 0,23 dpa at333 and 573 K. Electrical resistivity......, based on the production bias model (PBM) were carried out to study the details of evolution of cavitieswith and without helium generation. The phenomena of dislocation decoration and raft formation, which are important for understanding radiation hardening and plastic flow localization, have been...... studied using the Kinetic Monte Carlo (KMC) code during arealistic dynamic irradiation of bcc iron at 300 K. Molecular dynamics (MD) simulations have been carried out to study the stress dependencies of dislocation velocity and drag coefficient for an edge dislocation decorated with small SIA loops...

  15. Investigation in clinical potential of polarization sensitive optical coherence tomography in laryngeal tumor model study

    Science.gov (United States)

    Zhou, Xin; Oak, Chulho; Ahn, Yeh-Chan; Kim, Sung Won; Tang, Shuo

    2018-02-01

    Polarization-sensitive optical coherence tomography (PS-OCT) is capable of measuring tissue birefringence. It has been widely applied to access the birefringence in tissues such as skin and cartilage. The vocal cord tissue consists of three anatomical layers from the surface to deep inside, the epithelium that contains almost no collagen, the lamina propria that is composed with abundant collagen, and the vocalis muscle layer. Due to the variation in the organization of collagen fibers, the different tissue layers show different tissue birefringence, which can be evaluated by PS-OCT phase retardation measurement. Furthermore, collagen fibers in healthy connective tissues are usually well organized, which provides relatively high birefringence. When the collagen organization is destroyed by diseases such as tumor, the birefringence of the tissue will decrease. In this study, a rabbit laryngeal tumor model with different stages of tumor progression is investigated ex-vivo by PS-OCT. The PS-OCT images show a gradual decrease in birefringence from normal tissue to severe tumor tissue. A phase retardation slope-based analysis is conducted to distinguish the epithelium, lamina propria, and muscle layers, respectively. The phase retardation slope quantifies the birefringence in different layers. The quantitative study provides a more detailed comparison among different stages of the rabbit laryngeal tumor model. The PS-OCT result is validated by the corresponding histology images of the same samples.

  16. The investigation of HTGR fuel regeneration process

    Energy Technology Data Exchange (ETDEWEB)

    Lazarev, L N; Bertina, L E; Popik, V P; Isakov, V P; Alkhimov, N B; Pokhitonov, Yu A

    1985-07-01

    The aim of this report is the investigation of HTGR fuel regeneration. The operation in the technologic scheme of uranium extraction from fuel depleted elements is separation of fuel from graphite. Available methods of graphite matrix destruction are: mechanical destruction, chemical destruction, and burning. Mechanical destruction is done in combination with leaching or chlorination. Methods of chemical destruction of graphite matrix are not sufficiently studied. Most of the investigations nowadays sre devoted to removal of graphite by burning.

  17. The investigation of HTGR fuel regeneration process

    International Nuclear Information System (INIS)

    Lazarev, L.N.; Bertina, L.E.; Popik, V.P.; Isakov, V.P.; Alkhimov, N.B.; Pokhitonov, Yu.A.

    1985-01-01

    The aim of this report is the investigation of HTGR fuel regeneration. The operation in the technologic scheme of uranium extraction from fuel depleted elements is separation of fuel from graphite. Available methods of graphite matrix destruction are: mechanical destruction, chemical destruction, and burning. Mechanical destruction is done in combination with leaching or chlorination. Methods of chemical destruction of graphite matrix are not sufficiently studied. Most of the investigations nowadays sre devoted to removal of graphite by burning

  18. Investigating compliance with SME-friendly procurement policy

    OpenAIRE

    Flynn, Anthony

    2016-01-01

    This study investigates compliance with SME-friendly policy in public procurement. Two research questions guide the investigation. The first is the extent to which policy is being complied with. The results, which are based on 349 public buyer survey responses, reveal compliance to be moderate; indicated by a mean score of 14.54 out of 22 on the compliance index. The second question concerns the impact of institutional forces on policy compliance. A predictive model informed by institutional ...

  19. Synthesis, spectroscopic investigations, DFT studies, molecular docking and antimicrobial potential of certain new indole-isatin molecular hybrids: Experimental and theoretical approaches

    Science.gov (United States)

    Almutairi, Maha S.; Zakaria, Azza S.; Ignasius, P. Primsa; Al-Wabli, Reem I.; Joe, Isaac Hubert; Attia, Mohamed I.

    2018-02-01

    Indole-isatin molecular hybrids 5a-i have been synthesized and characterized by different spectroscopic methods to be evaluated as new antimicrobial agents against a panel of Gram positive bacteria, Gram negative bacteria, and moulds. Compound 5h was selected as a representative example of the prepared compounds 5a-i to perform computational investigations. Its vibrational properties have been studied using FT-IR and FT-Raman with the aid of density functional theory approach. The natural bond orbital analysis as well as HOMO and LUMO molecular orbitals investigations of compound 5h were carried out to explore its possible intermolecular delocalization or hyperconjugation and its possible interactions with the target protein. Molecular docking of compound 5h predicted its binding mode with the fungal target protein.

  20. An empirical investigation on factors influencing customer loyalty and their relationships with quality of services: A case study of insurance firm

    Directory of Open Access Journals (Sweden)

    Rostam Pourrahidi

    2014-01-01

    Full Text Available In this paper, we present an empirical investigation to study the effect of various factors influencing customer loyalty and quality of services on customer satisfaction and customer loyalty. The proposed study is implemented in one of Iranian insurance firms by choosing a sample of 171 randomly selected customers of this insurance firm. We use SERVQUAL standard questionnaire to measure customer satisfaction. The study examines three hypotheses associated with the proposed study using one-way t-student as well as path analysis, and the results have confirmed all three hypotheses. The study also uses Freedman test to rank the most important factors and detects that value was the most important issue followed by trust, customer satisfaction, empathy, value and resistance to change.

  1. The CoLaus study: a population-based study to investigate the epidemiology and genetic determinants of cardiovascular risk factors and metabolic syndrome

    Directory of Open Access Journals (Sweden)

    Stirnadel Heide A

    2008-03-01

    Full Text Available Abstract Background Cardiovascular diseases and their associated risk factors remain the main cause of mortality in western societies. In order to assess the prevalence of cardiovascular risk factors (CVRFs in the Caucasian population of Lausanne, Switzerland, we conducted a population-based study (Colaus Study. A secondary aim of the CoLaus study will be to determine new genetic determinants associated with CVRFs. Methods Single-center, cross-sectional study including a random sample of 6,188 extensively phenotyped Caucasian subjects (3,251 women and 2,937 men aged 35 to 75 years living in Lausanne, and genotyped using the 500 K Affymetrix chip technology. Results Obesity (body mass index ≥ 30 kg/m2, smoking, hypertension (blood pressure ≥ 140/90 mmHg and/or treatment, dyslipidemia (high LDL-cholesterol and/or low HDL-cholesterol and/or high triglyceride levels and diabetes (fasting plasma glucose ≥ 7 mmol/l and/or treatment were present in 947 (15.7%, 1673 (27.0%, 2268 (36.7%, 2113 (34.2% and 407 (6.6% of the participants, respectively, and the prevalence was higher in men than in women. In both genders, the prevalence of obesity, hypertension and diabetes increased with age. Conclusion The prevalence of major CVRFs is high in the Lausanne population in particular in men. We anticipate that given its size, the depth of the phenotypic analysis and the availability of dense genome-wide genetic data, the CoLaus Study will be a unique resource to investigate not only the epidemiology of isolated, or aggregated CVRFs like the metabolic syndrome, but can also serve as a discovery set, as well as replication set, to identify novel genes associated with these conditions.

  2. Human based roots of failures in nuclear events investigations

    Energy Technology Data Exchange (ETDEWEB)

    Ziedelis, Stanislovas; Noel, Marc; Strucic, Miodrag [Commission of the European Communities, Petten (Netherlands). European Clearinghouse on Operational Experience Feedback for Nuclear Power Plants

    2012-10-15

    This paper aims for improvement of quality of the event investigations in the nuclear industry through analysis of the existing practices, identifying and removing the existing Human and Organizational Factors (HOF) and management related barriers. It presents the essential results of several studies performed by the European Clearinghouse on Operational Experience. Outcomes of studies are based on survey of currently existing event investigation practices typical for nuclear industry of 12 European countries, as well as on insights from analysis of numerous event investigation reports. System of operational experience feedback from information based on event investigation results is not enough effective to prevent and even to decrease frequency of recurring events due to existing methodological, HOF-related and/or knowledge management related constraints. Besides that, several latent root causes of unsuccessful event investigation are related to weaknesses in safety culture of personnel and managers. These weaknesses include focus on costs or schedule, political manipulation, arrogance, ignorance, entitlement and/or autocracy. Upgrades in safety culture of organization's personnel and its senior management especially seem to be an effective way to improvement. Increasing of competencies, capabilities and level of independency of event investigation teams, elaboration of comprehensive software, ensuring of positive approach, adequate support and impartiality of management could also facilitate for improvement of quality of the event investigations. (orig.)

  3. Human based roots of failures in nuclear events investigations

    International Nuclear Information System (INIS)

    Ziedelis, Stanislovas; Noel, Marc; Strucic, Miodrag

    2012-01-01

    This paper aims for improvement of quality of the event investigations in the nuclear industry through analysis of the existing practices, identifying and removing the existing Human and Organizational Factors (HOF) and management related barriers. It presents the essential results of several studies performed by the European Clearinghouse on Operational Experience. Outcomes of studies are based on survey of currently existing event investigation practices typical for nuclear industry of 12 European countries, as well as on insights from analysis of numerous event investigation reports. System of operational experience feedback from information based on event investigation results is not enough effective to prevent and even to decrease frequency of recurring events due to existing methodological, HOF-related and/or knowledge management related constraints. Besides that, several latent root causes of unsuccessful event investigation are related to weaknesses in safety culture of personnel and managers. These weaknesses include focus on costs or schedule, political manipulation, arrogance, ignorance, entitlement and/or autocracy. Upgrades in safety culture of organization's personnel and its senior management especially seem to be an effective way to improvement. Increasing of competencies, capabilities and level of independency of event investigation teams, elaboration of comprehensive software, ensuring of positive approach, adequate support and impartiality of management could also facilitate for improvement of quality of the event investigations. (orig.)

  4. The Gene-Diet Attica investigation on childhood obesity (GENDAI) : overview of the study design

    NARCIS (Netherlands)

    Papoutsakis, Constantina; Vidra, Nikoleta V; Hatzopoulou, Ioanna; Tzirkalli, Maria; Farmaki, Anastasia-Eleni; Evagelidaki, Evagelia; Kapravelou, Garifallia; Kontele, Ioanna G; Skenderi, Katerina P; Yannakoulia, Mary; Dedoussis, George V; Vidra, Nikoletta

    BACKGROUND: There is limited evidence on the role of genetic and environmental factors in the etiology of childhood obesity, a major health problem worldwide. METHODS: The Gene-Diet Attica Investigation on childhood obesity (GENDAI) evaluates the contributions to and pivotal interactions of genetic,

  5. Outcomes of Infrainguinal Revascularizations with Endovascular First Strategy in Critical Limb Ischemia

    Energy Technology Data Exchange (ETDEWEB)

    Jens, Sjoerd, E-mail: s.jens@amc.uva.nl [Academic Medical Center, Department of Radiology (Netherlands); Conijn, Anne P., E-mail: a.p.conijn@amc.uva.nl; Frans, Franceline A., E-mail: f.a.frans@amc.uva.nl [Academic Medical Center, Departments of Radiology and Surgery (Netherlands); Nieuwenhuis, Marieke B. B., E-mail: m.b.nieuwenhuis@amc.uva.nl; Met, Rosemarie, E-mail: rosemariemet@hotmail.com [Academic Medical Center, Department of Radiology (Netherlands); Koelemay, Mark J. W., E-mail: m.j.koelemaij@amc.uva.nl; Legemate, Dink A., E-mail: d.a.legemate@amc.uva.nl [Academic Medical Center, Department of Surgery (Netherlands); Bipat, Shandra, E-mail: s.bipat@amc.uva.nl; Reekers, Jim A., E-mail: j.a.reekers@amc.uva.nl [Academic Medical Center, Department of Radiology (Netherlands)

    2015-06-15

    PurposeThis study was designed to study the outcome of infrainguinal revascularization in patients with critical limb ischemia (CLI) in an institution with a preference towards endovascular intervention first in patients with poor condition, unfavourable anatomy for surgery, no venous material for bypass, and old age.MethodsA prospective, observational cohort study was conducted between May 2007 and May 2010 in patients presenting with CLI. At baseline, the optimal treatment was selected, i.e., endovascular or surgical treatment. In case of uncertainty about the preferred treatment, a multidisciplinary team (MDT) was consulted. Primary endpoints were quality of life and functional status 6 and 12 months after initial intervention, assessed by the VascuQol and AMC Linear Disability Score questionnaires, respectively.ResultsIn total, 113 patients were included; 86 had an endovascular intervention and 27 had surgery. During follow-up, 41 % underwent an additional ipsilateral revascularisation procedure. For the total population, and endovascular and surgery subgroups, the VascuQol sum scores improved after 6 and 12 months (p < 0.01 for all outcomes) compared with baseline. The functional status improved (p = 0.043) after 12 months compared with baseline for the total population. Functional status of the surgery subgroup improved significantly after 6 (p = 0.031) and 12 (p = 0.044) months, but not that of the endovascular subgroup.ConclusionsOverall, the strategy of performing endovascular treatment first in patients with poor condition, unfavourable anatomy for surgery, no venous material for bypass, and old age has comparable or even slightly better results compared with the BASIL trial and other cohort studies. All vascular groups should discuss whether their treatment strategy should be directed at treating CLI patients preferably endovascular first and consider implementing an MDT to optimize patient outcomes.

  6. Investigation on nuclide migration behaviors

    International Nuclear Information System (INIS)

    Baik, Minhoon; Park, Chungkyun; Kim, Seungsoo

    2012-04-01

    In this study, we investigated the properties of geochemical reactions and sorption of high-level radionuclides and highly-mobile radionuclides in deep geological disposal environments. We also analyzed the dissolution properties of pyro wastes and constructed databases for the geochemical reactions and sorption for the safety assessment of HLW disposal. Technologies for measuring diffusion depths of radionuclides through fracture surfaces and rock matrix were developed in KURT conditions and their diffusion properties were analyzed and evaluated. The combined reactions of radionuclide/mineral/microbe in deep disposal environments were investigated and the effects of microbe on the radionuclide migration and disposal system behaviors were evaluated. In-situ solute migration system and on-line monitoring system were installed in KURT and the migration and retardation behaviors of various solutes and their interaction with fracture-filling materials were investigated. Basic properties of KURT groundwater colloids were analyzed using various methods. In addition, in-situ colloid migration experiments through a rock fracture were carried out and the developed migration model was verified. We have participated in Colloid Formation and Migration (CFM) international joint project in GTS and obtained reliability for our research results by comparing research results each other

  7. Investigating the Effect of Cultural Values on National Identity; (Case Study of Kerman’s Citizens

    Directory of Open Access Journals (Sweden)

    Hamid Nassaj

    2015-06-01

    Full Text Available National identity is the most comprehensive and important level of identity in all social systems, which is influential in all domains of culture, society and politics. Considering the significance of national identity as the most component of social order and integrity, the present study investigates the indices of national identity. Accordingly, the effect of cultural values on citizens’ attitudes towards national identity is to be studied. The present study is a survey research and the required data were collected via a researcher-made questionnaire. The population included the youth aged 16 to 40 years old in Kerman City, among whom 270 participants were selected as the sample size. The results of the research indicate that the degree of values of pluralism, patriarchy, power distance and avoidance of uncertainty are at relatively high levels. Furthermore, citizens’ national identity is at the moderate level. In addition, the findings indicate that the effect of variables of pluralism and power distance has significant effects on citizens’ national identity, and the coefficient and direction of the effect of this two variables on national identity is positive. In other words, participants who enjoy pluralist cultural values have more degree of national identity than those who have individualist characteristics and the first group are more likely to be located at higher classes of national identity than the second group. Also, the results indicate that participants who have cultural values with high power distance have more degree of national identity than those who have cultural characteristics with low degree of power distance. The findings indicate that variables of risk-taking and patriarchy have no significant effect on the degree of citizens’ national identity.

  8. Feasibility study report for Operable Unit 4: Fernald Environmental Management Project, Fernald, Ohio: Remedial investigation and feasibility study: Volume 3: Final report

    International Nuclear Information System (INIS)

    1994-02-01

    This report documents the Feasibility Study (FS) phase of the Fernald Environmental Management Project (FEMP) Operable Unit 4 Remedial Investigation/Feasibility Study (RI/FS) Program. The FEMP, formerly known as the Feed Materials Production Center (FMPC), is a US Department of Energy (DOE) facility that operated from 1952 to 1989. The facility's primarily function was to provide high purity uranium metal products to support United States defense programs. Production operations were suspended in 1989 to focus on environmental restoration and waste management activities at the facility. The RI/FS is being conducted pursuant to the terms of a Consent Agreement between DOE and the US Environmental Protection Agency (EPA) under Sections 120 and 106(a) of the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), as amended. The Ohio Environmental Protection Agency (OEPA) is also participating in the RI/FS process at the FEMP through direct involvement in program review meetings and technical review of project documentation. The objective of the RI/FS process is to gather information to support an informed risk management decision regarding which remedy appears to be the most appropriate action for addressing the environmental concerns identified at the FEMP. This volume contains appendices F--J

  9. Students' Perceptions of Learning Geography through Group Investigation in Singapore

    Science.gov (United States)

    Tan, Ivy Geok-Chin; Sharan, Shlomo; Lee, Christine Kim-Eng

    2005-01-01

    This study examines students' perceptions of the Group Investigation method of cooperative learning. A total of 142 students (62 low-achievers and 80 high-achievers) from two schools worked in cooperative learning groups during a period of over six weeks using the Group Investigation method. At the end of the study, they were asked to write their…

  10. A preliminary study for investigating idiopatic normal pressure hydrocephalus by means of statistical parameters classification of intracranial pressure recordings.

    Science.gov (United States)

    Calisto, A; Bramanti, A; Galeano, M; Angileri, F; Campobello, G; Serrano, S; Azzerboni, B

    2009-01-01

    The objective of this study is to investigate Id-iopatic Normal Pressure Hydrocephalus (INPH) through a multidimensional and multiparameter analysis of statistical data obtained from accurate analysis of Intracranial Pressure (ICP) recordings. Such a study could permit to detect new factors, correlated with therapeutic response, which are able to validate a predicting significance for infusion test. The algorithm developed by the authors computes 13 ICP parameter trends on each of the recording, afterward 9 statistical information from each trend is determined. All data are transferred to the datamining software WEKA. According to the exploited feature-selection techniques, the WEKA has revealed that the most significant statistical parameter is the maximum of Single-Wave-Amplitude: setting a 27 mmHg threshold leads to over 90% of correct classification.

  11. Geological mapping of investigation trench OL-TK14 at the Olkiluoto study site, Eurajoki, SW Finland

    International Nuclear Information System (INIS)

    Nordbaeck, N.

    2007-12-01

    Geological mapping of investigation trench OL-TK14 was carried out by the Geological Survey of Finland at the Olkiluoto study site, Eurajoki, as part of Posiva Oy's site investigation programme for the development of an underground repository for nuclear waste. The E-W striking, ca. 215 m long trench is located in the eastern part of the Olkiluoto Island adjacent to boreholes OL-KR40 and OL-KR45. The trench was cleaned with a pressure washer and pressurized air. The rock types were determined macroscopically. Five samples were also investigated microscopically. The main rock type in the trench is veined gneiss. A few less than 0.5 m wide coarsegrained pegmatitic granite dykes are also encountered. Furthermore a large number of mica gneiss, quartz gneiss and skarn inclusions are present in the veined gneiss, being often elongated and parallel to the foliation. The most dominant tectonic feature is the foliation S2 and associated intense granitic leucosome veining. The foliation strikes ENE-WSW and dips steeply towards SES. Intensely to moderately banded rocks dominate the trench. The sparse F3 folds observed in OL-TK14 are small-scale tight folds in leucosome veins. A large-scale (10 m) open bending of the foliation that could be a result of D4 folding was also observed. Shearbands and other signs of ductile shearing were observed on many locations in the trench and in the eastern part there is a high-grade ductile shear zone intersection. During the fracture mapping, all fractures intersecting the central thread were investigated and a total of 684 fractures were recorded. The average fracture density of the trench is 3.18 fractures/m. On the basis of fracture orientations three main sets can be distinguished: 1) a set striking N-S with vertical dip, 2) a ENE-WSW striking set with varying dips towards the SSE (parallel to the foliation) and 3) a NE-SW striking set with sub-vertical dip towards the SE or the NW. Most of the measured fractures are short due to the

  12. The Daunting Career of the Physician-Investigator.

    Science.gov (United States)

    McKinney, Ross E

    2017-10-01

    For many years, physician-investigators have had a particularly difficult time with their academic careers, so that they have been labeled an endangered species. In this Invited Commentary, the author defines three career paths for physician-investigators-clinical researcher, clinician-scientist, and physician-scientist. Each of these pathways has common and distinct challenges that should be studied and potential improvements that should be evaluated through pilot research projects.The first challenge that all physician-investigators face is securing funding. Physicians are funded by their clinical activities, which often lures physician-investigators to increase their clinical work, particularly when research funding from the National Institutes of Health is difficult to secure and seemingly arbitrarily granted. The second challenge is an appointments, promotion, and tenure system that is not responsive to the needs of faculty working across clinical care and research, particularly when it comes to evaluating team science. Physician-investigators not working full-time in either discipline then may have trouble being promoted. The third challenge is the increasing burdens of clinical activities, particularly with the advent of electronic medical records.In this issue, two articles address overcoming the challenges faced by physician-investigators, one from the National Institutes of Health to grow the workforce and the other to offer organizational and individual solutions to support these investigators in faculty roles. These solutions are encouraging, but data about the extent of the challenges and the potential effects of the solutions are needed to make the physician-investigator career path less daunting.

  13. Investigating the relationship between Malaysian rugby sevens ...

    African Journals Online (AJOL)

    The objective of this study is is to investigate the relationship between rugbgby match officials physical fitness to their perfor formance. 132 rugby side match official seven wewere selected as the respondent of the study. ANOANOVA indicated no significant differences [F = (3, 128) = 0.322, p = 0.809] in physical fitness ac ...

  14. An Empirical Investigation into Programming Language Syntax

    Science.gov (United States)

    Stefik, Andreas; Siebert, Susanna

    2013-01-01

    Recent studies in the literature have shown that syntax remains a significant barrier to novice computer science students in the field. While this syntax barrier is known to exist, whether and how it varies across programming languages has not been carefully investigated. For this article, we conducted four empirical studies on programming…

  15. Pilot study on indoor climate investigation and computer simulation in historical museum building: Amerongen Castle, the Netherlands

    Directory of Open Access Journals (Sweden)

    Raha Sulaiman

    2010-12-01

    Full Text Available The indoor climate is one of the most important factors contributing to climate-induced damage to the building materials and cultural collections of a monumental building. The Dutch monumental building - Amerongen Castle, and the collections housed in it show severe deterioration caused by inappropriate historical indoor environment. Assessments of the indoor climate, especially on the room temperature and relative humidity, are necessary to analyze the causes and impacts of climate change. As the building was flooded in year 1993 and 1996, extra attention is paid to investigate the effects of flooding to it. This pilot study was aimed to identify the buildup linkages between the known past, historical data on indoor environment and indoor climate performance in the building through simulation based-prediction. This paper focuses on the methodology of indoor climate investigation from the past to the current situation. A hypothesis was developed on backcasting-based prediction simulation which can be used to identify the accepted historical indoor climate where during those times there probably was no damage to the building and the collection. A simulation method based on heat, air and moisture transport is used with the HAMBase program. The computer model representing the Grand Salon of Amerongen Castle was calibrated by comparing real measurements to simulation results. It shows that the differences were only to the minimum of -1.8C and maximum of 3.2C. The data for the historical outdoor weather files was obtained by interpolating outdoor ancient climatology constructed by MATLAB. Based on archival research, indoor thermal history was gathered as input for the profiles used in simulation. Further, the calibrated computer model can be used to simulate past indoor climate and investigate the process of the deterioration of the room and the collections mainly due to the fluctuation of indoor temperature and relative humidity. At the end

  16. A dynamics investigation into edge plasma turbulence

    International Nuclear Information System (INIS)

    Thomsen, H.

    2002-08-01

    The present experimental work investigates plasma turbulence in the edge region of magnetized high-temperature plasmas. A main topic is the turbulent dynamics parallel to the magnetic field, where hitherto only a small data basis existed, especially for very long scale lengths in the order of ten of meters. A second point of special interest is the coupling of the dynamics parallel and perpendicular to the magnetic field. This anisotropic turbulent dynamics is investigated by two different approaches. Firstly, spatially and temporally high-resolution measurements of fluctuating plasma parameters are investigated by means of two-point correlation analysis. Secondly, the propagation of signals externally imposed into the turbulent plasma background is studied. For both approaches, Langmuir probe arrays were utilized for diagnostic purposes. (orig.)

  17. Investigation corporate governance characteristics on risk taking: A case study of private banks listed in Tehran Stock Exchange

    Directory of Open Access Journals (Sweden)

    Mohammad Khodaei Valahzaghard

    2013-02-01

    Full Text Available During the past few years, there have been tremendous works on detecting the relationship between banks performance and the number of seats on board of directors. Board of directors of banks is responsible for shareholders ownership’s interest. In this study, governance and ownership characteristics affecting risk appetite on some private banks listed in Tehran Stock Exchange is studied. The study investigates 12 private banks for a period 2005-2011 based on the implementation of some regression analysis using panel data. The results indicate that the effect of five major shareholders on risk-taking is positive and significant. The effect of institutional ownership on risk-taking is negative and significant. Effects of other variables, including the percentage of ownership concentration, return on assets and the logarithm of cash from operations (CFO on risk-taking of the private banks are not significant. The effects of board size, reliance on debt and log of assets on risk-taking are significantly negative among private banks in Iran. These results indicate that shareholders that are institutional investors play a key role in monitoring managers.

  18. Closure of the Spent Fuel Repository in Forsmark - Studies of alternative concepts for sealing of ramp, shafts and investigation boreholes

    Energy Technology Data Exchange (ETDEWEB)

    Gylling, Bjoern [SKB AB, Stockholm (Sweden); Luterkort, David [SGI, Stockholm (Sweden); Johansson, Roland [Miljoe- och Energikonsult AB, Ekeroe (Sweden)

    2012-12-15

    In March 2011, SKB submitted applications under the Nuclear Activities Act and the Environmental Code for the construction and operation of a final repository for spent nuclear fuel in Forsmark. An important supporting document for the application under the Nuclear Activities Act was the SR-Site safety assessment. As a part of the work with the application and as background material for SR-Site, SKB prepared production reports, including the closure production report. The closure production report presented definitions, requirements and design premises, a reference design and the initial state for repository closure. SR-Site evaluated the reference design and related design premises that were presented in the closure production report. SR-Site thereby concluded that the design premises on which the reference design were based are adequate. Relaxing the requirements would require additional sensitivity analyses focusing on the hydraulic properties of the access, main and transport tunnels. SR-Site further concluded that the reference design could likely be simplified without violating the current design premises. Furthermore, additional simplifications could probably be made if the design premises could be revised. This has been studied in the project 'Closure - concept studies', whose results are presented in this report. SR-Site also evaluated the reference design for investigation boreholes that is presented in the production report. The evaluation showed that the impact of improper borehole seals is very moderate. Further, SR-Site concludes that the current design premises are appropriate but possibly too strict, since even open boreholes seem to have a limited impact on the groundwater flow in the repository. Since it might be difficult to inspect the outcome of the current design of borehole sealing, it could be of interest to assess whether a solution that may result in higher effective permeability of the borehole seals would provide sufficiently

  19. The exceptional ethics of the investigator-subject relationship.

    Science.gov (United States)

    Sachs, Benjamin

    2010-02-01

    This article concerns the validity of six canonical rules