WorldWideScience

Sample records for purpose research complex

  1. Multiple purpose research complex on the basis of electron accelerators and terahertz free electron laser

    International Nuclear Information System (INIS)

    Kulipanov, G.N.

    2009-01-01

    In this report the basic positioning parameters of multiple purpose research complex are presented, the list of potential experiments and technological uses on the example of results received in the multiuser center of G.I. Budker Institut of nuclear physics Siberian department of the Russian Academy of Sciences is discussed. This research complex is directed on work in the big universities and nano technology centers. Electron accelerators is intended for development of electron-beam technologies different material modification, for production of nano powder, nano materials and solution of ecological tasks. In this work the project of multiple purpose research complex on the basis of new generation electron accelerator Il-14 and workable terahertz free electron laser is suggested. Terahertz free electron laser will be used for researches in the sphere of physics and chemistry, biology and medicine, nanotechnology engineering and different methods of nanodiagnostics.

  2. Improving Education through Research? From Effectiveness, Causality and Technology to Purpose, Complexity and Culture

    Science.gov (United States)

    Biesta, Gert

    2016-01-01

    This paper focuses on the role of research in the improvement of educational practice. I use the "10 Principles for Effective Pedagogy," which were formulated on the basis of research conducted in the UK's Teacher and Learning Research Programme as an example to highlight some common problems in the discussion about research and…

  3. Multi purpose research reactor

    International Nuclear Information System (INIS)

    Raina, V.K.; Sasidharan, K.; Sengupta, Samiran; Singh, Tej

    2006-01-01

    At present Dhruva and Cirus reactors provide the majority of research reactor based facilities to cater to the various needs of a vast pool of researchers in the field of material sciences, physics, chemistry, bio sciences, research and development work for nuclear power plants and production of radio isotopes. With a view to further consolidate and expand the scope of research and development in nuclear and allied sciences, a new 20 MWt multi purpose research reactor is being designed. This paper describes some of the design features and safety aspects of this reactor

  4. Multi-Purpose Storage Complex description

    International Nuclear Information System (INIS)

    Nyman, D.H.

    1993-01-01

    The Multi-Purpose Storage Complex will provide interim storage of radioactive material (irradiated fuel, cesium/strontium capsules, plutonium residuals, canisters of vitrified high-level waste glass, and other radioactive material) at the Hanford Site near Richland, Washington. A Storage Preparation and Shipping Facility is included that will have the capability to stabilize failed metal fuel, segregate high-level solid waste, and package/repackage any of the materials for interim storage/final disposal or subsequent processing. Current technology, both domestic and foreign, will be adapted with the expectation that no new technology will be required. This cost-effective approach will use fuel casks, transport systems, and/or modular vaults that have been licensed in the United States. The complex will have a central control room, and appropriate safeguards and security measures will be incorporated. A specific design objective will be to minimize the amount of secondary waste

  5. Needs of research for regulatory purposes

    International Nuclear Information System (INIS)

    Wanner, H.

    2010-01-01

    question whether or not it is the duty of the regulator to carry out such complementary work is the subject of controversial discussions. A further issue is the source of the budget from which research for regulatory purposes should be funded since frequent sources of funding are the waste producers and the national budgets. The question of how much regulatory research is needed is difficult to answer on a general basis. It appears obvious that the regulator must achieve the objectives of competence and independence. The research needed for this purpose is the least the regulator must undertake. The verification of key safety issues and the investigation of issues not addressed by the implementer may be considered as optional

  6. Using action research for complex research initiatives

    CSIR Research Space (South Africa)

    Greeff, M

    2009-12-01

    Full Text Available the research process of such a complex research initiative. Action research is one research method that lends itself to these complex projects. The paper uses the Ability Based Technology Interventions (AbTi) research project as a case study to analyse...

  7. The Social Purposes of Mass Communications Research: A Transatlantic Perspective.

    Science.gov (United States)

    Blumler, Jay G.

    Purposes and alternative forms of mass communications research are explored in this four-part presentation. Part One examines the origins of, and the differences between, two conflicting types of research: administrative research, in which the mass media are perceived as neutral tools, capable of serving a wide range of purposes; and critical…

  8. Small Multi-Purpose Research Facility (SMiRF)

    Data.gov (United States)

    Federal Laboratory Consortium — The Small Multi-Purpose Research Facility (SMiRF) evaluates the performance of the thermal protection systems required to provide long-term storage (up to 10 years)...

  9. A Small Acoustic Goniometer for General Purpose Research.

    Science.gov (United States)

    Pook, Michael L; Loo, Sin Ming

    2016-04-29

    Understanding acoustic events and monitoring their occurrence is a useful aspect of many research projects. In particular, acoustic goniometry allows researchers to determine the source of an event based solely on the sound it produces. The vast majority of acoustic goniometry research projects used custom hardware targeted to the specific application under test. Unfortunately, due to the wide range of sensing applications, a flexible general purpose hardware/firmware system does not exist for this purpose. This article focuses on the development of such a system which encourages the continued exploration of general purpose hardware/firmware and lowers barriers to research in projects requiring the use of acoustic goniometry. Simulations have been employed to verify system feasibility, and a complete hardware implementation of the acoustic goniometer has been designed and field tested. The results are reported, and suggested areas for improvement and further exploration are discussed.

  10. Purposive Selection and the Quality of Qualitative IS Research

    DEFF Research Database (Denmark)

    Marton, Attila

    2013-01-01

    for the evaluation of qualitative research, although equally important, have not received equal attention. Drawing on literature from behavioral and social science, this paper discusses methodological concepts of evaluating qualitative research by focusing on techniques to purposefully select data for analysis......As qualitative research has found broad acceptance within the IS community, the methodological discourse has turned its attention to questions concerning the quality of qualitative research mostly emphasizing the development of how-to guidelines for good practice. By contrast, criteria....... In particular, the technique of corpus construction will be introduced, which was specifically designed as an evaluation criterion for qualitative research. Adapted from linguistics, corpus construction offers an alternative that is functionally equivalent to statistical sampling techniques in terms...

  11. Hydrodynamic analysis of floating platform for special purposes under complex water environment

    Science.gov (United States)

    Ma, Guang-ying; Yao, Yun-long

    2018-03-01

    This article studied a new floating offshore platform for special purposes, which was assembled by standard floating modules. By using ANSYS AQWA software, the hydrodynamic model of the platform was established. The time history responses of the platform motions and the cable tension forces were calculate under complex water environments, such as wind, wave, current and mooring. The results showed that the tension of the four cables are far less than the breaking tension of the cable, so that the cable will not break. This study can be referenced by the relevant researchers and engineers.

  12. Combustion & Laser Diagnostics Research Complex (CLDRC)

    Data.gov (United States)

    Federal Laboratory Consortium — Description: The Combustion and Laser Diagnostics Research Complex (CLRDC) supports the experimental and computational study of fundamental combustion phenomena to...

  13. Software architecture for a multi-purpose real-time control unit for research purposes

    Science.gov (United States)

    Epple, S.; Jung, R.; Jalba, K.; Nasui, V.

    2017-05-01

    A new, freely programmable, scalable control system for academic research purposes was developed. The intention was, to have a control unit capable of handling multiple PT1000 temperature sensors at reasonable accuracy and temperature range, as well as digital input signals and providing powerful output signals. To take full advantage of the system, control-loops are run in real time. The whole eight bit system with very limited memory runs independently of a personal computer. The two on board RS232 connectors allow to connect further units or to connect other equipment, as required in real time. This paper describes the software architecture for the third prototype that now provides stable measurements and an improvement in accuracy compared to the previous designs. As test case a thermal solar system to produce hot tap water and assist heating in a single-family house was implemented. The solar fluid pump was power-controlled and several temperatures at different points in the hydraulic system were measured and used in the control algorithms. The software architecture proved suitable to test several different control strategies and their corresponding algorithms for the thermal solar system.

  14. Flow characteristics of Korea multi-purpose research reactor

    Energy Technology Data Exchange (ETDEWEB)

    Heonil Kim; Hee Taek Chae; Byung Jin Jun; Ji Bok Lee [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1995-09-01

    The construction of Korea Multi-purpose Research Reactor (KMRR), a 30 MW{sub th} open-tank-in-pool type, is completed. Various thermal-hydraulic experiments have been conducted to verify the design characteristics of the KMRR. This paper describes the commissioning experiments to determine the flow distribution of KMRR core and the flow characteristics inside the chimney which stands on top of the core. The core flow is distributed to within {+-}6% of the average values, which is sufficiently flat in the sense that the design velocity in the fueled region is satisfied. The role of core bypass flow to confine the activated core coolant in the chimney structure is confirmed.

  15. THE CONTRIBUTION OF COMPLEXITY, ACCURACY AND FLUENCY TO LANGUAGE FOR SPECIFIC PURPOSES

    Directory of Open Access Journals (Sweden)

    Anthony Rausch

    2016-03-01

    Full Text Available This paper will outline an instructional approach that proposes a Complexity, Accuracy, Fluency (CAF paradigm as a means of providing learners with the CAF-based communication consciousness and CAF-oriented manipulative skills that are increasingly important in language use in Language for Specific Purposes. Given the complex combinations of communicative tasks, communicative formats and communicative circumstances that accompany the wide-ranging and various contexts of contemporary professional communication, communicative competence demands a combinative consciousness and informed application of Complexity, Accuracy and Fluency as a communication paradigm. Viewed as a combination of its three components, a CAF paradigm constitutes a fundamental ‘information, language and communication’ triad that can guide professional language use in any communicative circumstance. Viewed as a communicative skill set, the CAF triad implies the capability to adjust specific elements and aspects of information, language and communication as needed for a communicative task, whether in oral or print communication and regardless of task category. Adjusting complexity in this context refers to both content and language complexity. Adjusting accuracy refers to the conventions that dictate appropriate or acceptable language in a given context. Finally, adjusting fluency refers to a sense of communicative fluency, that which yields either smooth and persuasive language as in a native-speaker normative view or explicit and clearly explanatory language as necessary in some communicative encounters. The need to manipulate these three components depends on circumstance variables such as objective, available time, audience characteristics and the degree of detail desired. This paper will outline this combinative CAF notion as background to a materials development project being undertaken in a Japanese university, introducing the specifics of an Extended Reading Aloud

  16. MYRRHA – A multi-purpose fast spectrum research reactor

    International Nuclear Information System (INIS)

    Aït Abderrahim, Hamid; Baeten, Peter; De Bruyn, Didier; Fernandez, Rafael

    2012-01-01

    Highlights: ► Historical evolution of the MYRRHA project. ► Detail design of the MYRRHA Accelerator Driven System. ► Irradiation performance simulation of the MYRRHA ADS. - Abstract: MYRRHA (Multi-purpose hYbrid Research Reactor for High-tech Applications) is the flexible experimental Accelerator-Driven System (ADS) currently under development at SCK⋅CEN and will replace the Material Testing Reactor (MTR) BR2. The MYRRHA facility is currently being developed with the aid of the FP7-project “Central Design Team” and will be as a flexible irradiation facility, able to work in both subcritical and critical modes. In this way, MYRRHA will allow fuel developments for innovative reactor systems, material developments for GEN IV systems, material developments for fusion reactors, radioisotope production for medical and industrial applications, and Si-doping. MYRRHA will also demonstrate the full concept of Accelerator Driven Systems by coupling the requisite three components (accelerator, spallation target and subcritical reactor) at reasonable power level to allow operation feedback, scalable to an industrial demonstrator and allow for the study of efficient transmutation of high-level nuclear waste. Since MYRRHA is based on the heavy liquid metal technology, Lead–Bismuth Eutectic, it will be able to significantly contribute to the development of Lead Fast Reactor (LFR) technology. Further, in critical mode, MYRRHA will play the role of European Technology Pilot Plant in the path forward for LFR. In this paper we present the historical perspectives, international and high profile membership within the consortium of the MYRRHA project and the rationale for the design choices are presented. Also, the latest configuration of the reactor system is described together with the different irradiation capabilities. More specifically, the possibilities and performances for fuel irradiations are presented in detail.

  17. Quantifying the complexity of medical research.

    Science.gov (United States)

    Rodriguez-Esteban, Raul; Loging, William T

    2013-11-15

    A crucial phenomenon of our times is the diminishing marginal returns of investments in pharmaceutical research and development. A potential reason is that research into diseases is becoming increasingly complex, and thus more burdensome, for humans to handle. We sought to investigate whether we could measure research complexity by analyzing the published literature. Through the text mining of the publication record of multiple diseases, we have found that the complexity and novelty of disease research has been increasing over the years. Surprisingly, we have also found that research on diseases with higher publication rate does not possess greater complexity or novelty than that on less-studied diseases. We have also shown that the research produced about a disease can be seen as a differentiated area of knowledge within the wider biomedical research. For our analysis, we have conceptualized disease research as a parallel multi-agent search in which each scientific agent (a scientist) follows a search path based on a model of a disease. We have looked at trends in facts published for diseases, measured their diversity and turnover using the entropy measure and found similar patterns across disease areas. raul.rodriguez-esteban@roche.com.

  18. The relationship between cost system complexity, purposes of use, and cost system effectiveness

    NARCIS (Netherlands)

    Schoute, M.

    2009-01-01

    This paper uses survey data from 133 Dutch, medium-sized manufacturing firms to examine the associations between cost system complexity (in terms of the applied overhead absorption procedures), purposes of use, and cost system effectiveness. First, factor analysis identifies two underlying

  19. Researching contexts, practices and pedagogies in English for academic purposes

    CERN Document Server

    Blaj-Ward, L

    2014-01-01

    This book is a point of reference for EAP professionals planning to conduct or commission research into learning, teaching, professional development or quality assurance in EAP. It draws on academic and professional debates to inspire further research and practical initiatives to enhance EAP provision.

  20. Complex Plasma Research Under Extreme Conditions

    International Nuclear Information System (INIS)

    Ishihara, Osamu

    2008-01-01

    Complex plasma research under extreme conditions is described. The extreme conditions include low-dimensionality for self-organized structures of dust particles, dust magnetization in high magnetic field, criticality in phase transition, and cryogenic environment for Coulomb crystals and dust dynamics.

  1. Fatigue analysis of assembled marine floating platform for special purposes under complex water environments

    Science.gov (United States)

    Ma, Guang-ying; Yao, Yun-long

    2018-03-01

    In this paper, the fatigue lives of a new type of assembled marine floating platform for special purposes were studied. Firstly, by using ANSYS AQWA software, the hydrodynamic model of the platform was established. Secondly, the structural stresses under alternating change loads were calculated under complex water environments, such as wind, wave, current and ice. The minimum fatigue lives were obtained under different working conditions. The analysis results showed that the fatigue life of the platform structure can meet the requirements

  2. Topical problems of corrosion research for nuclear power purposes

    International Nuclear Information System (INIS)

    Eremias, B.

    1978-01-01

    Currently, research is focused on stress corrosion, intergranular corrosion, corrosion in water and steam, hydrogen-induced corrosion and corrosion in liquid sodium. The effort to limit stress corrosion resulted in the application of high nickel content austenitic steels. In these steels, the susceptibility to stress corrosion is mainly affected by previous heat treatment and the presence of chloride ions. Attention is also paid to medium and high-alloy chromium steels and susceptibility is studied to intergranular corrosion and stress corrosion. Of low-alloy steels the 21/4Cr-1Mo type steels stabilized with Nb or nonstabilized are studied with respect to decarburization kinetics and changes in mechanical properties in the presence of hydrogen. Of nonferrous metals zirconium alloys are studied used as cladding materials for fuel elements, mainly Zircaloy 2 and 4, with regard to their resistance to high-temperature oxidation, high-pressure steam action, etc. (J.F.)

  3. Custom mentholation of commercial cigarettes for research purposes

    Directory of Open Access Journals (Sweden)

    Ian C. MacGregor

    2014-01-01

    Full Text Available In the U.S. menthol remains the sole permitted characterizing cigarette flavor additive in part because efforts to link menthol cigarette use to increased tobacco-related disease risk have been inconclusive. To perform definitive studies, cigarettes that differ only in menthol content are required, yet these are not commercially available. We prepared research cigarettes differing only in menthol content by deposition of l-menthol vapor directly onto commercial nonmenthol cigarettes, and developed a method to measure a cigarette's menthol and nicotine content. With our custom-mentholation technique we achieved the desired moderately high menthol content (as compared to commercial brands of 6.7 ± 1.0 mg/g (n = 25 without perturbing the cigarettes’ nicotine content (17.7 ± 0.7 mg/g [n = 25]. We also characterized other pertinent attributes of our custom-mentholated cigarettes, including percent transmission of menthol and nicotine to mainstream smoke and the rate of loss of menthol over time during storage at room temperature. We are currently using this simple mentholation technique to investigate the differences in human exposure to selected chemicals in cigarette smoke due only to the presence of the added menthol. Our cigarettes will also aid in the elucidation of the effects of menthol on the toxicity of tobacco smoke.

  4. Geo-scientific database for research and development purposes

    International Nuclear Information System (INIS)

    Tabani, P.; Mangeot, A.; Crabol, V.; Delage, P.; Dewonck, S.; Auriere, C.

    2012-01-01

    Document available in extended abstract form only. The Research and Development Division must manage, secure and reliable manner, a large number of data from scientific disciplines and diverse means of acquisition (observations, measurements, experiments, etc.). This management is particularly important for the Underground research Laboratory, the source of many recording continuous measurements. Thus, from its conception, Andra has implemented two management tools of scientific information, the 'Acquisition System and Data Management' [SAGD] and GEO database with its associated applications. Beyond its own needs, Andra wants to share its achievements with the scientific community, and it therefore provides the data stored in its databases or samples of rock or water when they are available. Acquisition and Data Management (SAGD) This system manages data from sensors installed at several sites. Some sites are on the surface (piezometric, atmospheric and environmental stations), the other are in the Underground Research Laboratory. This system also incorporates data from experiments in which Andra participates in Mont Terri Laboratory in Switzerland. S.A.G.D fulfils these objectives by: - Make available in real time on a single system, with scientists from Andra but also different partners or providers who need it, all experimental data from measurement points - Displaying the recorded data on temporal windows and specific time step, - Allowing remote control of the experimentations, - Ensuring the traceability of all recorded information, - Ensuring data storage in a data base. S.A.G.D has been deployed in the first experimental drift at -445 m in November 2004. It was subsequently extended to the underground Mont Terri laboratory in Switzerland in 2005, to the entire surface logging network of the Meuse / Haute-Marne Center in 2008 and to the environmental network in 2011. All information is acquired, stored and manage by a software called Geoscope. This software

  5. RIAR experimental base development concept 1. Multi-purpose pyrochemical complex for experimental justification of innovative closed fuel cycle technologies

    Energy Technology Data Exchange (ETDEWEB)

    Bychkov, A.V.; Kormilitsyn, M.V. [Research Institute of Atomic Reactors, Dimitrovgrad-10, Ulyanovsk region, 433510 (Russian Federation)

    2009-06-15

    The principles of closed FC arrangement on the basis of non-aqueous methods allow the development of production addressing two tasks simultaneously: production of fresh fuel and reprocessing of irradiated fuel, that makes it possible to achieve the industrial level of implementation of closed FC of fast reactors of new generation in a series variant of standardized process modules on the basis of innovative pyrochemical high-effective compact technologies. For the purpose of experimental justification of innovative closed FC technologies at the RIAR site, the existing experimental base is being updated and a multi-purpose pyrochemical complex is developed: - Experimental complex of pyrochemical molten salt facilities to reprocess all types of spent fuel (MOX, nitride, metallic, IMF) of fast reactors of new generation (BN-800, MBIR, BREST). - Experimental complex of facilities to master a gas-fluoride technology of reprocessing intractable fuel, research reactors fuel and thermal SNF. - Transition of the existing facility of pyro-electrochemical production of MOX fuel into the mode of reprocessing of the BN-800 MOX SNF. - Renovation of the facilities for production of fuel elements from experimental, re-fabricated, innovative and high-active fuel - a complex of heavy and glove boxes - to produce experimental fuel elements and targets with MAs on the basis of oxides (vibro and pellets), mixed nitrides, metal alloys and inert matrices in heavy boxes. - Upgrading of the complex for mastering and demonstration of the processes for radioactive waste management and spent fuel pyrochemical reprocessing. The report covers main concept and design solutions, plans and schedule of the program for development of pyrochemical complex for experimental justification of innovative closed FC technologies. (authors)

  6. SYNTACTIC COMPLEXITY IN THE READING MATERIALS OF ENGLISH FOR ACADEMIC PURPOSES LEVELS 1 – 3

    Directory of Open Access Journals (Sweden)

    Widdy Wijanti

    2017-10-01

    Full Text Available LLT Journal: A Journal on Language and Language Teaching Open Journal Systems LLT Journal ISSNs: e-ISSN: 2579-9533 (electronic p-ISSN: 1410-7201 (print User Username Password Remember me Journal Content Search Search Scope Browse By Issue By Author By Title Other Journals Font Size Make font size smaller Make font size default Make font size larger LLT Journal Barcode TOOLS FULL PAPER GUIDELINES Article Tools Print this article Indexing metadata How to cite item Email this article (Login required Email the author (Login required About The Author Widdy Wijanti Sampoerna University, Jakarta Indonesia OUR CONTACT LLT Journal English Language Education Sanata Dharma University Yogyakarta, Indonesia For more details, please visit: LLT Journal Contact Address Home About Login Register Search Current Archives Author Guidelines Editorial Team Focus and Scope Publication Ethics Author Index Originality Screening Indexing and Abstracting Review Process Article Processing Charges Article Submission Charges Publishing Rights Peer Reviewers Home > Vol 20, No 2 (2017 > Wijanti SYNTACTIC COMPLEXITY IN THE READING MATERIALS OF ENGLISH FOR ACADEMIC PURPOSES LEVELS 1 – 3 Widdy Wijanti Abstract In Indonesia, English is still considered as a foreign language and has become a crucial subject of study especially in the university level. For this reason, English for Academic Purposes has been conducted in the first year of college level for many years. Unfortunately, although many Asian countries including Indonesia have run the EAP course, the output is that there are still many Indonesian students who do not meet the vocabulary size and syntactic complexity that are expected while their learning process in the university. This results lower grades that they have in their assignments. Therefore, the recent study is aimed at evaluating the reading materials of EAP, especially in measuring the syntactic complexity containing in the texts as it is strongly believed in

  7. A commentary on domestic animals as dual-purpose models that benefit agricultural and biomedical research.

    Science.gov (United States)

    Ireland, J J; Roberts, R M; Palmer, G H; Bauman, D E; Bazer, F W

    2008-10-01

    Research on domestic animals (cattle, swine, sheep, goats, poultry, horses, and aquatic species) at land grant institutions is integral to improving the global competitiveness of US animal agriculture and to resolving complex animal and human diseases. However, dwindling federal and state budgets, years of stagnant funding from USDA for the Competitive State Research, Education, and Extension Service National Research Initiative (CSREES-NRI) Competitive Grants Program, significant reductions in farm animal species and in numbers at land grant institutions, and declining enrollment for graduate studies in animal science are diminishing the resources necessary to conduct research on domestic species. Consequently, recruitment of scientists who use such models to conduct research relevant to animal agriculture and biomedicine at land grant institutions is in jeopardy. Concerned stakeholders have addressed this critical problem by conducting workshops, holding a series of meetings with USDA and National Institutes of Health (NIH) officials, and developing a white paper to propose solutions to obstacles impeding the use of domestic species as dual-purpose animal models for high-priority problems common to agriculture and biomedicine. In addition to shortfalls in research support and human resources, overwhelming use of mouse models in biomedicine, lack of advocacy from university administrators, long-standing cultural barriers between agriculture and human medicine, inadequate grantsmanship by animal scientists, and a scarcity of key reagents and resources are major roadblocks to progress. Solutions will require a large financial enhancement of USDA's Competitive Grants Program, educational programs geared toward explaining how research using agricultural animals benefits both animal agriculture and human health, and the development of a new mind-set in land grant institutions that fosters greater cooperation among basic and applied researchers. Recruitment of

  8. Purposeful Sampling for Qualitative Data Collection and Analysis in Mixed Method Implementation Research.

    Science.gov (United States)

    Palinkas, Lawrence A; Horwitz, Sarah M; Green, Carla A; Wisdom, Jennifer P; Duan, Naihua; Hoagwood, Kimberly

    2015-09-01

    Purposeful sampling is widely used in qualitative research for the identification and selection of information-rich cases related to the phenomenon of interest. Although there are several different purposeful sampling strategies, criterion sampling appears to be used most commonly in implementation research. However, combining sampling strategies may be more appropriate to the aims of implementation research and more consistent with recent developments in quantitative methods. This paper reviews the principles and practice of purposeful sampling in implementation research, summarizes types and categories of purposeful sampling strategies and provides a set of recommendations for use of single strategy or multistage strategy designs, particularly for state implementation research.

  9. Purposeful sampling for qualitative data collection and analysis in mixed method implementation research

    Science.gov (United States)

    Palinkas, Lawrence A.; Horwitz, Sarah M.; Green, Carla A.; Wisdom, Jennifer P.; Duan, Naihua; Hoagwood, Kimberly

    2013-01-01

    Purposeful sampling is widely used in qualitative research for the identification and selection of information-rich cases related to the phenomenon of interest. Although there are several different purposeful sampling strategies, criterion sampling appears to be used most commonly in implementation research. However, combining sampling strategies may be more appropriate to the aims of implementation research and more consistent with recent developments in quantitative methods. This paper reviews the principles and practice of purposeful sampling in implementation research, summarizes types and categories of purposeful sampling strategies and provides a set of recommendations for use of single strategy or multistage strategy designs, particularly for state implementation research. PMID:24193818

  10. General-Purpose Computation with Neural Networks: A Survey of Complexity Theoretic Results

    Czech Academy of Sciences Publication Activity Database

    Šíma, Jiří; Orponen, P.

    2003-01-01

    Roč. 15, č. 12 (2003), s. 2727-2778 ISSN 0899-7667 R&D Projects: GA AV ČR IAB2030007; GA ČR GA201/02/1456 Institutional research plan: AV0Z1030915 Keywords : computational power * computational complexity * perceptrons * radial basis functions * spiking neurons * feedforward networks * reccurent networks * probabilistic computation * analog computation Subject RIV: BA - General Mathematics Impact factor: 2.747, year: 2003

  11. Quantifying complexity in translational research: an integrated approach.

    Science.gov (United States)

    Munoz, David A; Nembhard, Harriet Black; Kraschnewski, Jennifer L

    2014-01-01

    The purpose of this paper is to quantify complexity in translational research. The impact of major operational steps and technical requirements is calculated with respect to their ability to accelerate moving new discoveries into clinical practice. A three-phase integrated quality function deployment (QFD) and analytic hierarchy process (AHP) method was used to quantify complexity in translational research. A case study in obesity was used to usability. Generally, the evidence generated was valuable for understanding various components in translational research. Particularly, the authors found that collaboration networks, multidisciplinary team capacity and community engagement are crucial for translating new discoveries into practice. As the method is mainly based on subjective opinion, some argue that the results may be biased. However, a consistency ratio is calculated and used as a guide to subjectivity. Alternatively, a larger sample may be incorporated to reduce bias. The integrated QFD-AHP framework provides evidence that could be helpful to generate agreement, develop guidelines, allocate resources wisely, identify benchmarks and enhance collaboration among similar projects. Current conceptual models in translational research provide little or no clue to assess complexity. The proposed method aimed to fill this gap. Additionally, the literature review includes various features that have not been explored in translational research.

  12. Upscaling from research watersheds: an essential stage of trustworthy general-purpose hydrologic model building

    Science.gov (United States)

    McNamara, J. P.; Semenova, O.; Restrepo, P. J.

    2011-12-01

    Highly instrumented research watersheds provide excellent opportunities for investigating hydrologic processes. A danger, however, is that the processes observed at a particular research watershed are too specific to the watershed and not representative even of the larger scale watershed that contains that particular research watershed. Thus, models developed based on those partial observations may not be suitable for general hydrologic use. Therefore demonstrating the upscaling of hydrologic process from research watersheds to larger watersheds is essential to validate concepts and test model structure. The Hydrograph model has been developed as a general-purpose process-based hydrologic distributed system. In its applications and further development we evaluate the scaling of model concepts and parameters in a wide range of hydrologic landscapes. All models, either lumped or distributed, are based on a discretization concept. It is common practice that watersheds are discretized into so called hydrologic units or hydrologic landscapes possessing assumed homogeneous hydrologic functioning. If a model structure is fixed, the difference in hydrologic functioning (difference in hydrologic landscapes) should be reflected by a specific set of model parameters. Research watersheds provide the possibility for reasonable detailed combining of processes into some typical hydrologic concept such as hydrologic units, hydrologic forms, and runoff formation complexes in the Hydrograph model. And here by upscaling we imply not the upscaling of a single process but upscaling of such unified hydrologic functioning. The simulation of runoff processes for the Dry Creek research watershed, Idaho, USA (27 km2) was undertaken using the Hydrograph model. The information on the watershed was provided by Boise State University and included a GIS database of watershed characteristics and a detailed hydrometeorological observational dataset. The model provided good simulation results in

  13. Research on image complexity evaluation method based on color information

    Science.gov (United States)

    Wang, Hao; Duan, Jin; Han, Xue-hui; Xiao, Bo

    2017-11-01

    In order to evaluate the complexity of a color image more effectively and find the connection between image complexity and image information, this paper presents a method to compute the complexity of image based on color information.Under the complexity ,the theoretical analysis first divides the complexity from the subjective level, divides into three levels: low complexity, medium complexity and high complexity, and then carries on the image feature extraction, finally establishes the function between the complexity value and the color characteristic model. The experimental results show that this kind of evaluation method can objectively reconstruct the complexity of the image from the image feature research. The experimental results obtained by the method of this paper are in good agreement with the results of human visual perception complexity,Color image complexity has a certain reference value.

  14. Rigour and Complexity in Educational Research. Conducting Educational Research

    Science.gov (United States)

    Berry, Kathleen; Kincheloe, Joe

    2004-01-01

    What does it mean to engage in rigorous research? What does a researcher need to know to produce such research? What is specifically involved in multiple method bricolage research? In an era where talk abounds about scientific rigour and evidence-based research in education, this groundbreaking book presents a new and compelling examination of…

  15. Maintaining excellence: planning a new multi-purpose research reactor for Canada

    International Nuclear Information System (INIS)

    Whitlock, J.

    2011-01-01

    This paper outlines the need for a multi-purpose research reactor for Canada. The main objective of this paper is to stimulate a discussion and increase the profile for the need to develop a national strategy to meet the long term research reactor needs.

  16. Research of polysaccharide complexes from asteraceae family plants

    Directory of Open Access Journals (Sweden)

    Світлана Михайлівна Марчишин

    2015-10-01

    Full Text Available Aim of research. Depth study of polysaccharides in some little-known plant species of Asteraceae family is pressing question, considering that polysaccharides are important biologically active compounds widely used in pharmaceutical and medical practice as remedies and preventive medications. The aim of research was to determinate both quantitative content and monomeric composition of polysaccharide complexes from Asteraceae family plant species – Tagetes genus, Arnica genus, and Bellis genus.Materials and methods. Determination of polysaccharides was carried out by the precipitation reaction, using 96 % ethyl alcohol P and Fehling's solution after acid hydrolysis; quantitative content of this group of compounds was determined by gravimetric analysis. On purpose to identify the monomeric composition hydrolysis under sulfuric acid conditions was conducted. Qualitative monomeric composition of polysaccharides after hydrolysis was carried out by paper chromatography method in n-Butanol – Pyridine – Distilled water P (6:4:3 system along with saccharides reference samples.Results. Polysaccharide complexes from Tagetes erecta, Tagetes patula, Tagetes tenuifolia, Arnica montana, Arnica foliosa, wild and cultivated Bellis perennis herbs were studied. Water-soluble polysaccharides and pectin fractions were isolated from studied objects; their quantitative content and monomeric composition were determined.Conclusion. The highest amount of water-soluble polysaccharides was found in cultivated Bellis perennis herb (10,13 %, the highest amount of pectin compounds – in Tagetes tenuifolia herb (13,62 %; the lowest amount of water-soluble polysaccharides and pectin compounds was found in Arnica montana herb (4,61 % and Tagetes patula herb (3,62 %, respectively. It was found that polysaccharide complexes from all studied species include glucose and arabinose

  17. Classroom-oriented research from a complex systems perspective

    Directory of Open Access Journals (Sweden)

    Diane Larsen-Freeman

    2016-09-01

    Full Text Available Bringing a complex systems perspective to bear on classroom-oriented research challenges researchers to think differently, seeing the classroom ecology as one dynamic system nested in a hierarchy of such systems at different levels of scale, all of which are spatially and temporally situated. This article begins with an introduction to complex dynamic systems theory, in which challenges to traditional ways of conducting classroom research are interwoven. It concludes with suggestions for research methods that are more consistent with the theory. Research does not become easier when approached from a complex systems perspective, but it has the virtue of reflecting the way the world works.

  18. Complexity, Methodology and Method: Crafting a Critical Process of Research

    Science.gov (United States)

    Alhadeff-Jones, Michel

    2013-01-01

    This paper defines a theoretical framework aiming to support the actions and reflections of researchers looking for a "method" in order to critically conceive the complexity of a scientific process of research. First, it starts with a brief overview of the core assumptions framing Morin's "paradigm of complexity" and Le…

  19. Semantic Support for Complex Ecosystem Research Environments

    Science.gov (United States)

    Klawonn, M.; McGuinness, D. L.; Pinheiro, P.; Santos, H. O.; Chastain, K.

    2015-12-01

    As ecosystems come under increasing stresses from diverse sources, there is growing interest in research efforts aimed at monitoring, modeling, and improving understanding of ecosystems and protection options. We aimed to provide a semantic infrastructure capable of representing data initially related to one large aquatic ecosystem research effort - the Jefferson project at Lake George. This effort includes significant historical observational data, extensive sensor-based monitoring data, experimental data, as well as model and simulation data covering topics including lake circulation, watershed runoff, lake biome food webs, etc. The initial measurement representation has been centered on monitoring data and related provenance. We developed a human-aware sensor network ontology (HASNetO) that leverages existing ontologies (PROV-O, OBOE, VSTO*) in support of measurement annotations. We explicitly support the human-aware aspects of human sensor deployment and collection activity to help capture key provenance that often is lacking. Our foundational ontology has since been generalized into a family of ontologies and used to create our human-aware data collection infrastructure that now supports the integration of measurement data along with simulation data. Interestingly, we have also utilized the same infrastructure to work with partners who have some more specific needs for specifying the environmental conditions where measurements occur, for example, knowing that an air temperature is not an external air temperature, but of the air temperature when windows are shut and curtains are open. We have also leveraged the same infrastructure to work with partners more interested in modeling smart cities with data feeds more related to people, mobility, environment, and living. We will introduce our human-aware data collection infrastructure, and demonstrate how it uses HASNetO and its supporting SOLR-based search platform to support data integration and semantic browsing

  20. Replication Research in Comparative Genre Analysis in English for Academic Purposes

    Science.gov (United States)

    Basturkmen, Helen

    2014-01-01

    In recent years a number of comparative studies based on an established approach to genre analysis have been published in the English for Academic Purposes (EAP) literature. Studies in this emerging strand of research typically aim to identify how the rhetorical structure of a particular genre (a text type) or part of a genre may vary across…

  1. Geocapabilities: Toward an International Framework for Researching the Purposes and Values of Geography Education

    Science.gov (United States)

    Solem, Michael; Lambert, David; Tani, Sirpa

    2013-01-01

    GeoCapabilities is a transatlantic collaborative project for researching the purposes and values of geography education through a "capabilities approach." Inspired by the writings of philosopher Amartya Sen and economist Martha Nussbaum, the capabilities approach provides a normative framework for understanding the broader aims of…

  2. The robustness of k0-NAA in large multi-purpose research reactors

    International Nuclear Information System (INIS)

    Attila Stopic; Bennett, J.W.

    2014-01-01

    The challenges and opportunities associated with performing k 0 -NAA in high-powered, multi-purpose research reactors are examined and recommendations are made concerning the conditions that need to be met in such facilities in order to allow the potential for this method of elemental analysis to be fully realised. (author)

  3. Copyright Law in Australia--Fair Dealing for Research or Study Purposes.

    Science.gov (United States)

    Khan, Anwar (Andy); Hancock, Philip

    2001-01-01

    Explores several issues involving provisions of the Australian copyright law that allow for "fair dealing for the purpose of research and study" in the use of copyrighted materials. Discusses liability of libraries for improper oversight of illegal photocopying of books and other copyrighted materials. Reviews recent efforts to improve…

  4. Complexity and interdisciplinary approaches to environmental research

    Science.gov (United States)

    Kammen, Daniel M.

    2013-03-01

    The launch of volume 8 of Environmental Research Letters (ERL) comes at a critical time in terms of innovations and exciting areas of science, but particularly in the areas linking environmental research and action. The most recent climate change Conference of the Parties meeting (COP), in Doha in December 2012, has now come and gone. As has been dissected in the press, very little was accomplished. Some will see this as a failure, as I do, and others will reasonably enough note that this meeting, the 18th such COP was1 never intended to be a milestone moment. The current plan, in fact, is for a 'post-Kyoto' international climate agreement to be adopted only at the COP20 summit in December 2015. As we lead up to COP20, and potentially other regional or national approaches to climate protection, innovations in science, innovations in policy tools, and political commitment must come together. The science of climate change only continues to get clearer and clearer, and bleaker [1]. Later this year the IPCC will release its Fifth Assessment Report, AR5. The draft versions are out for review now. ERL has published a number of papers on climate change science, mitigation and adaptation, but one area where the world needs a particular focus is on the nexus of science and action. A summary of the Intergovernmental Panel on Climate Change's findings from the first assessment report (FAR; 1990) to the latest report is presented in figure 1. This graphic is specifically not about the scientific record alone. What is most important about this figure is the juxtaposition of the language of science and the language of ... language. Figure 1. Figure 1. A superposition of the state of climate science in three key data sets, and the dates of the first, second, third and fourth assessment reports (FAR, SAR, TAR, and AR4, respectively) plotted as vertical lines. On the right are the key statements from each of these reports, along with the conclusion of the Special Report on

  5. The Use of Facebook in Recruiting Participants for Health Research Purposes: A Systematic Review.

    Science.gov (United States)

    Whitaker, Christopher; Stevelink, Sharon; Fear, Nicola

    2017-08-28

    Social media is a popular online tool that allows users to communicate and exchange information. It allows digital content such as pictures, videos and websites to be shared, discussed, republished and endorsed by its users, their friends and businesses. Adverts can be posted and promoted to specific target audiences by demographics such as region, age or gender. Recruiting for health research is complex with strict requirement criteria imposed on the participants. Traditional research recruitment relies on flyers, newspaper adverts, radio and television broadcasts, letters, emails, website listings, and word of mouth. These methods are potentially poor at recruiting hard to reach demographics, can be slow and expensive. Recruitment via social media, in particular Facebook, may be faster and cheaper. The aim of this study was to systematically review the literature regarding the current use and success of Facebook to recruit participants for health research purposes. A literature review was completed in March 2017 in the English language using MEDLINE, EMBASE, Web of Science, PubMed, PsycInfo, Google Scholar, and a hand search of article references. Papers from the past 12 years were included and number of participants, recruitment period, number of impressions, cost per click or participant, and conversion rate extracted. A total of 35 studies were identified from the United States (n=22), Australia (n=9), Canada (n=2), Japan (n=1), and Germany (n=1) and appraised using the Critical Appraisal Skills Programme (CASP) checklist. All focused on the feasibility of recruitment via Facebook, with some (n=10) also testing interventions, such as smoking cessation and depression reduction. Most recruited young age groups (16-24 years), with the remaining targeting specific demographics, for example, military veterans. Information from the 35 studies was analyzed with median values being 264 recruited participants, a 3-month recruitment period, 3.3 million impressions, cost

  6. Analytical and ethical complexities in video game research

    DEFF Research Database (Denmark)

    Andersen, Mads Lund; Chimiri, Niklas Alexander; Søndergaard, Dorte Marie

    Session: Sociomaterial complexities in digital-analog spaces Abstract: Analytical and ethical complexities in video game research A central issue that video game research seldom explicitly articulates is the ethical complexities involved in its empirical and analytical work. The presentation...... explores common research questions posed and analytical foci chosen by video game researchers subscribing to either the media effects tradition, represented by (ref.) or to interdisciplinary Game Studies. Both fields, which tend to depict themselves as polar-opposites, build on ethical assumptions...... of theoretical or analytical arrogance. The relevance of acknowledging and situating ethical complexity becomes pertinent when alternatively taking a sociomaterial perspective on doing empirical and analytical work on video gaming. From an agential realist point of view, for instance, a researcher...

  7. An example of the utilization of the military nuclear complex of peaceful purposes

    International Nuclear Information System (INIS)

    Zaleski, P.

    1994-01-01

    One of the major difficulties in military conversion is to find cases that are realistic from the point of view of politics, economics, financing and society. This report proposes an example which is believed to meet the above criteria. The suggestion is to use manpower, and to some extent the installations (laboratories, factories) of Russian military nuclear complex to build a small series of fast neutron plutonium storage reactor power plants. These plants with a unit output of some 800 MWe would have two main functions: store the excess of Russian military grade plutonium and produce electricity at competitive prices

  8. Research teams as complex systems: implications for knowledge management

    NARCIS (Netherlands)

    Vasileiadou, E.

    2012-01-01

    The recent increase in research collaboration creates the need to better understand the interaction between individual researchers and the collaborative team. The paper elaborates the conceptualisation of research teams as complex systems which emerge out of the local interactions of individual

  9. User oriented design features of Korea Multi-purpose Research Reactor and its utilization plan

    International Nuclear Information System (INIS)

    Kim, Byungkoo; Jun, Byungjin

    1994-01-01

    Construction of a 30 MW class Korea Multi-purpose Research Reactor (KMRR) is near its completion and expected to reach initial criticality by the end of 1994 at KAERI Taejon site. As Korea will become one of developed countries during the lifetime of this reactor and many worldwide high performance research reactors of the first generation are reaching end of life, it is believed that KMRR will meet the increasing domestic needs to utilize high performance research reactor and its worldwide role will be important as well. In reactor design, effort has been focused on optimization which can satisfy various future utilization demands as much as possible with enhanced safety as a basic requirement. Light water cooled and heavy water reflected compact core using low enriched and high uranium loaded fuel, computer controlled operation, etc. are expected to provide truly multi-purpose user environments with stable high quality neutron flux. High level experimental facilities and equipment for reactor fuel and material test, various studies using neutron beam, radioisotope production, semiconductor doping, neutron activation analysis, etc., will be completed in parallel with the reactor or gradually depending on users' needs. When KMRR becomes fully operational, it will not only serve the domestic users but also be a valuable tool for a worldwide research community using a research reactor

  10. The Use of Facebook in Recruiting Participants for Health Research Purposes: A Systematic Review

    OpenAIRE

    Whitaker, Christopher; Stevelink, Sharon; Fear, Nicola

    2017-01-01

    Background: Social media is a popular online tool that allows users to communicate and exchange information. It allows digitalcontent such as pictures, videos and websites to be shared, discussed, republished and endorsed by its users, their friends andbusinesses. Adverts can be posted and promoted to specific target audiences by demographics such as region, age or gender.Recruiting for health research is complex with strict requirement criteria imposed on the participants. Traditional resear...

  11. Design of a multi-purpose fragment screening library using molecular complexity and orthogonal diversity metrics

    Science.gov (United States)

    Lau, Wan F.; Withka, Jane M.; Hepworth, David; Magee, Thomas V.; Du, Yuhua J.; Bakken, Gregory A.; Miller, Michael D.; Hendsch, Zachary S.; Thanabal, Venkataraman; Kolodziej, Steve A.; Xing, Li; Hu, Qiyue; Narasimhan, Lakshmi S.; Love, Robert; Charlton, Maura E.; Hughes, Samantha; van Hoorn, Willem P.; Mills, James E.

    2011-07-01

    Fragment Based Drug Discovery (FBDD) continues to advance as an efficient and alternative screening paradigm for the identification and optimization of novel chemical matter. To enable FBDD across a wide range of pharmaceutical targets, a fragment screening library is required to be chemically diverse and synthetically expandable to enable critical decision making for chemical follow-up and assessing new target druggability. In this manuscript, the Pfizer fragment library design strategy which utilized multiple and orthogonal metrics to incorporate structure, pharmacophore and pharmacological space diversity is described. Appropriate measures of molecular complexity were also employed to maximize the probability of detection of fragment hits using a variety of biophysical and biochemical screening methods. In addition, structural integrity, purity, solubility, fragment and analog availability as well as cost were important considerations in the selection process. Preliminary analysis of primary screening results for 13 targets using NMR Saturation Transfer Difference (STD) indicates the identification of uM-mM hits and the uniqueness of hits at weak binding affinities for these targets.

  12. The Utilization of Dalat nuclear research reactor for education and training purposes

    International Nuclear Information System (INIS)

    Luong, Ba Vien; Nguyen, Nhi Dien; Le, Vinh Vinh; Nguyen, Xuan Hai

    2017-01-01

    The Dalat Nuclear Research Reactor (DNRR) with the nominal power of 500 kWt is today the unique one in Vietnam. It was designed for the purposes of radioisotope production, neutron activation analysis, basic and applied researches, and nuclear education and training. With the rising demand in development of human resources for utilization of atomic energy in the country, the DNRR has been playing an important role in the nuclear education and training for students from universities and professionals who are interested in reactor engineering. At present, the Dalat Nuclear Research Institute (DNRI) offers two types of training course utilizing the research reactor: an one-week practical training course is applied for undergraduate students and a two-week training course on reactor engineering is applied for the professionals. This paper presents the reactor facility and experiments performed at the DNRR for education and training purposes. In addition, the co-operation between the DNRI with national and international educational organizations for nuclear human resource development for national and regional demands is also mentioned in the paper. (author)

  13. Multi-purpose mid-plane manipulator for plasma surface interaction research in KSTAR

    Energy Technology Data Exchange (ETDEWEB)

    Son, S.H., E-mail: ssh0609@nfri.re.kr [National Fusion Research Institute, Daejeon 305-333 (Korea, Republic of); Hong, S.-H. [National Fusion Research Institute, Daejeon 305-333 (Korea, Republic of); Department of Electrical Engineering, HanYang University, Seoul 133-791 (Korea, Republic of); Department of Accelerator and Nuclear Fusion Physics and Engineering, Korea University of Science and Technology, Daejeon 305-333 (Korea, Republic of); Kim, Junghee [National Fusion Research Institute, Daejeon 305-333 (Korea, Republic of); Kim, Jun Young [National Fusion Research Institute, Daejeon 305-333 (Korea, Republic of); Department of Accelerator and Nuclear Fusion Physics and Engineering, Korea University of Science and Technology, Daejeon 305-333 (Korea, Republic of); Kim, H.S. [National Fusion Research Institute, Daejeon 305-333 (Korea, Republic of); Ding, F.; Luo, G.-N. [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei 1126 (China); Németh, J.; Zoletnik, S. [Institute for Particle and Nuclear Physics (RMI), Wigner RCP, Hungarian Academy of Sciences, Budapest (Hungary); Fenyvesi, A. [Institute for Nuclear Physis (MTA Atomki), Hungarian Academy of Sciences, Devrecent (Hungary); Pitts, R. [ITER Organization, Route de Vinon-surVerdon, 13115 Saint Paul-lez-Durance (France)

    2016-11-01

    Highlights: • A multi-purpose mid-plane manipulator system has been developed and installed at the mid-plane of the KSTAR vacuum vessel. • It presents mechanial structure and function for multi-purpose manipulator system. • The changeable head part allows change the samples and probe during inter-shot/day without breaking vacuum system in KSTAR which gives flexibility for various PSI studies in a campaign. - Abstract: A multi-purpose mid-plane manipulator system has been developed and installed at the mid-plane of the KSTAR vacuum vessel. The system serves as user facility which allows to cover various topics of researches in plasma-surface interaction (PSI) including material sample test and PSI diagnostic. The multi-purpose mid-plane manipulator system has a 4 m long cantilever structure with a 3 m long moving shaft. The system is equipped with a differential pumping system for the independent installation and removal of samples and diagnostic without vacuum break of KSTAR. The sample mounting head at the end of the shaft can reach the position of the outer boundary of ∼10 cm away from the last closed flux surface (LCFS). In this paper, selected PSI related experiments by using the manipulator are introduced.

  14. Multi-purpose mid-plane manipulator for plasma surface interaction research in KSTAR

    International Nuclear Information System (INIS)

    Son, S.H.; Hong, S.-H.; Kim, Junghee; Kim, Jun Young; Kim, H.S.; Ding, F.; Luo, G.-N.; Németh, J.; Zoletnik, S.; Fenyvesi, A.; Pitts, R.

    2016-01-01

    Highlights: • A multi-purpose mid-plane manipulator system has been developed and installed at the mid-plane of the KSTAR vacuum vessel. • It presents mechanial structure and function for multi-purpose manipulator system. • The changeable head part allows change the samples and probe during inter-shot/day without breaking vacuum system in KSTAR which gives flexibility for various PSI studies in a campaign. - Abstract: A multi-purpose mid-plane manipulator system has been developed and installed at the mid-plane of the KSTAR vacuum vessel. The system serves as user facility which allows to cover various topics of researches in plasma-surface interaction (PSI) including material sample test and PSI diagnostic. The multi-purpose mid-plane manipulator system has a 4 m long cantilever structure with a 3 m long moving shaft. The system is equipped with a differential pumping system for the independent installation and removal of samples and diagnostic without vacuum break of KSTAR. The sample mounting head at the end of the shaft can reach the position of the outer boundary of ∼10 cm away from the last closed flux surface (LCFS). In this paper, selected PSI related experiments by using the manipulator are introduced.

  15. Action research to promote medical students' motivation in an English for Specific Purposes class.

    Science.gov (United States)

    Dehnad, Afsaneh; Nasser, Hayedeh

    2014-01-01

    Action research is an attempt to seek immediate solutions to the problems experienced in educational settings. In this type of research, teachers are the researchers who intend to make instant reforms to develop, and improve their teaching styles and reflect on pedagogical practices. The purpose of this study was to conduct an action research to tackle the problem of students' low motivation in English classes at the medical school of Iran University of Medical Sciences in fall 2010. Participants of this study were 98 third-semester ESP students of medicine. To reform the situation and promote students' motivation to participate in classes more actively and eagerly, the researchers changed the syllabus by applying Kemmis and McTaggart's (1988) cyclical model of action research, and adopting task-based teaching. Data was collected by means of interviews with both teachers and students to determine the changes to be made in the syllabus, classroom observations to monitor students' behavioral changes, and a questionnaire to assess students' attitudes towards the changes. This research study had a number of valuable outcomes the most important of which was a change in classroom behavior of the students.

  16. Action research to promote medical students' motivation in an English for Specific Purposes class.

    Directory of Open Access Journals (Sweden)

    Afsaneh Dehnad

    2014-06-01

    Full Text Available Action research is an attempt to seek immediate solutions to the problems experienced in educational settings. In this type of research, teachers are the researchers who intend to make instant reforms to develop, and improve their teaching styles and reflect on pedagogical practices. The purpose of this study was to conduct an action research to tackle the problem of students' low motivation in English classes at the medical school of Iran University of Medical Sciences in fall 2010. Participants of this study were 98 third-semester ESP students of medicine. To reform the situation and promote students' motivation to participate in classes more actively and eagerly, the researchers changed the syllabus by applying Kemmis and McTaggart's (1988 cyclical model of action research, and adopting task-based teaching. Data was collected by means of interviews with both teachers and students to determine the changes to be made in the syllabus, classroom observations to monitor students' behavioral changes, and a questionnaire to assess students' attitudes towards the changes. This research study had a number of valuable outcomes the most important of which was a change in classroom behavior of the students.

  17. Addressing Underrepresentation in Sex Work Research: Reflections on Designing a Purposeful Sampling Strategy.

    Science.gov (United States)

    Bungay, Vicky; Oliffe, John; Atchison, Chris

    2016-06-01

    Men, transgender people, and those working in off-street locales have historically been underrepresented in sex work health research. Failure to include all sections of sex worker populations precludes comprehensive understandings about a range of population health issues, including potential variations in the manifestation of such issues within and between population subgroups, which in turn can impede the development of effective services and interventions. In this article, we describe our attempts to define, determine, and recruit a purposeful sample for a qualitative study examining the interrelationships between sex workers' health and the working conditions in the Vancouver off-street sex industry. Detailed is our application of ethnographic mapping approaches to generate information about population diversity and work settings within distinct geographical boundaries. Bearing in mind the challenges and the overwhelming discrimination sex workers experience, we scope recommendations for safe and effective purposeful sampling inclusive of sex workers' heterogeneity. © The Author(s) 2015.

  18. Automated complex for research of electric drives control

    Science.gov (United States)

    Avlasko, P. V.; Antonenko, D. A.

    2018-05-01

    In the article, the automated complex intended for research of various control modes of electric motors including the inductor motor of double-way feed is described. As a basis of the created complex, the National Instruments platform is chosen. The operating controller built in a platform is delivered with an operating system of real-time for creation of systems of measurement and management. The software developed in the environment of LabVIEW consists of several connected modules which are in different elements of a complex. Besides the software for automated management by experimental installation, the program complex is developed for modelling of processes in the electric drive. As a result there is an opportunity to compare simulated and received experimentally transitional characteristics of the electric drive in various operating modes.

  19. Research on the Fault Coefficient in Complex Electrical Engineering

    Directory of Open Access Journals (Sweden)

    Yi Sun

    2015-08-01

    Full Text Available Fault detection and isolation in a complex system are research hotspots and frontier problems in the reliability engineering field. Fault identification can be regarded as a procedure of excavating key characteristics from massive failure data, then classifying and identifying fault samples. In this paper, based on the fundamental of feature extraction about the fault coefficient, we will discuss the fault coefficient feature in complex electrical engineering in detail. For general fault types in a complex power system, even if there is a strong white Gaussian stochastic interference, the fault coefficient feature is still accurate and reliable. The results about comparative analysis of noise influence will also demonstrate the strong anti-interference ability and great redundancy of the fault coefficient feature in complex electrical engineering.

  20. The complex and transdisciplinarity thought as frames of scientific research

    Directory of Open Access Journals (Sweden)

    Elvio Galati

    2017-06-01

    Full Text Available The work aims to describe and support, from the methodological point of view, Edgar Morin’s complex thought and Basarab Nicolescu’s transdisciplinarity. It is structured based on the philosophical and logical contexts of multi-method; and then developing methodological ideas from transdisciplinarity and complexity. The methodology used is the documentation, taking into account articles on doctrine and teaching experience. There is discourse analysis, classification and interpretation, also creating categories. The implications of integrative, complex and transdisciplinary philosophy are seen, in a research design for Social Sciences. Transdisciplinary category of "property" is provided, adding it to the "production" category. Developing the complexity and transdisciplinarity as a methodology, "transdisciplinary instructions" arise, which are applied to research although they were originally thought for teaching. From the structure of the research design, unsystematic transdisciplinary methodological strategies and systematic strategies element by element of the research project are identified. As another result, the creation of the category of "General Theory / Interim Science" is added, approached from transdisciplinarity

  1. Accelerating complex for basic researches in the nuclear physics

    NARCIS (Netherlands)

    Dovbnya, A.N.; Guk, I.S.; Kononenko, S.G.; Peev, F.A.; Tarasenko, A.S.; Botman, J.I.M.

    2009-01-01

    In 2003 in NSC KIPT was begun the work on development the project of accelerator, base facility IHEPNP NSC KIPT electron recirculator SALO. The accelerator will be disposed in target hall of accelerator LU 2000 complex. It is projected first of all as facility for basic researches in the field of

  2. A Proposal for Critical-Pragmatic Pedagogical Approaches to English for Research Publication Purposes

    Directory of Open Access Journals (Sweden)

    James Corcoran

    2016-03-01

    Full Text Available Despite the increasing demands on many multilingual scholars outside the centre(s of scientific knowledge production to publish their research in international scholarly journals, the support for such academic writing for publication is uneven at best. Existing English for research publication purposes (ERPP instruction typically aims to aid multilingual scholars in achieving genre-based expectations and/or navigating the submission and review process, but it often does not address the politics of English-language knowledge production. In this paper, informed by an empirical case study and a theory building perspective, we address the need for a sustained program of courses/workshops for multilingual scholars in the (semi- periphery and propose a means of operationalizing a critical-pragmatic approach to such course/workshop content. Our empirically-driven model is informed by the results of a recent case study investigation into an intensive ERPP intervention designed to address multilingual Spanish-speaking L1 scholars’ challenges with writing research articles for publication in indexed (Web of Science international scientific journals. Our model lays the groundwork for a more critical approach to ERPP pedagogy, one that attempts to attend more fully to the needs of multilingual scholars within an asymmetrical market of global knowledge production.

  3. Neuropathic pain. Redefinition and a grading system for clinical and research purposes

    DEFF Research Database (Denmark)

    Treede, R.-D.; Jensen, Troels Staehelin; Campbell, J.N.

    2008-01-01

    potentially tissue-damaging stimuli. Pain may also arise by activity generated within the nervous system without adequate stimulation of its peripheral sensory endings. For this type of pain, the International Association for the Study of Pain introduced the term neuropathic pain, defined as "pai...... evidence from a neurologic examination. This grading system is proposed for clinical and research purposes....... initiated or caused by a primary lesion or dysfunction in the nervous system." While this definition has been useful in distinguishing some characteristics of neuropathic and nociceptive types of pain, it lacks defined boundaries. Since the sensitivity of the nociceptive system is modulated by its adequate...... activation (e.g., by central sensitization), it has been difficult to distinguish neuropathic dysfunction from physiologic neuroplasticity. We present a more precise definition developed by a group of experts from the neurologic and pain community: pain arising as a direct consequence of a lesion or disease...

  4. Research ethics in dissertations: ethical issues and complexity of reasoning.

    Science.gov (United States)

    Kjellström, S; Ross, S N; Fridlund, B

    2010-07-01

    Conducting ethically sound research is a fundamental principle of scientific inquiry. Recent research has indicated that ethical concerns are insufficiently dealt with in dissertations. To examine which research ethical topics were addressed and how these were presented in terms of complexity of reasoning in Swedish nurses' dissertations. Analyses of ethical content and complexity of ethical reasoning were performed on 64 Swedish nurses' PhD dissertations dated 2007. A total of seven ethical topics were identified: ethical approval (94% of the dissertations), information and informed consent (86%), confidentiality (67%), ethical aspects of methods (61%), use of ethical principles and regulations (39%), rationale for the study (20%) and fair participant selection (14%). Four of those of topics were most frequently addressed: the majority of dissertations (72%) included 3-5 issues. While many ethical concerns, by their nature, involve systematic concepts or metasystematic principles, ethical reasoning scored predominantly at lesser levels of complexity: abstract (6% of the dissertations), formal (84%) and systematic (10%). Research ethics are inadequately covered in most dissertations by nurses in Sweden. Important ethical concerns are missing, and the complexity of reasoning on ethical principles, motives and implications is insufficient. This is partly due to traditions and norms that discount ethical concerns but is probably also a reflection of the ability of PhD students and supervisors to handle complexity in general. It is suggested that the importance of ethical considerations should be emphasised in graduate and post-graduate studies and that individuals with capacity to deal with systematic and metasystematic concepts are recruited to senior research positions.

  5. The complexity of collaboration: Opportunities and challenges in contracted research

    Directory of Open Access Journals (Sweden)

    Marion Bowl

    2010-11-01

    Full Text Available This article explores some of the challenges of utilising collaborative research approaches when undertaking contracted research projects for government and non-government agencies in the adult and community education (ACE sector. To discuss these challenges, the article draws on three recent examples of research projects undertaken for ACE sector organisations in Aotearoa New Zealand. These challenges include managing relationships with the different parties to the research; dealing with conflicting expectations of funding agencies, commissioning organisations and practitioners; and ownership and dissemination of findings. We highlight the complexity of notions of collaboration and the importance of deliberate trust-building in establishing credibility. We also open up for discussion the thorny issues of who owns the right to disseminate research findings and how far should researchers’ and universities’ responsibilities extend to ensure that research findings are put in the public domain?

  6. Relationships between economic and technical research in nuclear power complex

    International Nuclear Information System (INIS)

    Drahny, M.; Martinek, J.

    1984-01-01

    The period from projecting and construction to operation and decommissioning of a nuclear power plant spans approximately 5a years. During this period it is necessary to resolve a range of technical, economic and social research problems. Even more complicated is the nuclear power complex as a whole. The respective technical and economic aspects are interactive and cannot be solved separately. It is therefore suggested that the respective national research and development program be linked with the national program of economic research, this both at the preparatory stage, in the course of work and during the evaluation of achieved results. (Ha)

  7. Considerations for conducting qualitative research with pediatric patients for the purpose of PRO development.

    Science.gov (United States)

    Patel, Zabin S; Jensen, Sally E; Lai, Jin-Shei

    2016-09-01

    To provide an overview of methodological considerations when conducting qualitative research with pediatric patients for the purpose of patient-reported outcome measure development A literature review of qualitative methods in pediatric measure development was completed. Eight clinicians providing care to pediatric patients were interviewed for their expert input. Thematic analysis of the literature and clinician interviews was used to identify themes for consideration. Findings from the literature and expert interviews emphasized the way in which cognitive, linguistic, and social developmental factors affect pediatric patients' understanding of their condition and ability to communicate about their experiences in an interview. There was consensus among the experts that traditional semi-structured interviews with children younger than eight lack characteristics necessary to yield meaningful information about condition and symptom report because they may fail to capture children's understanding and awareness of their condition and may limit their ability to express themselves comfortably. Our findings include recommended strategies to optimize data collected in qualitative interviews with pediatric patients, including modifications to the interview process to establish rapport, construction of interview questions to ensure they are developmentally appropriate, and the use of supplementary techniques to facilitate communication. When employing qualitative methods in pediatric measure development, interview guides, methods, and length require careful tailoring to ensure the child's perspectives are captured. This may be best achieved through research performed with narrow age bands that employs flexibility in methods to allow children a comfortable way in which to communicate about their experiences.

  8. Implications of complex adaptive systems theory for interpreting research about health care organizations.

    Science.gov (United States)

    Jordon, Michelle; Lanham, Holly Jordan; Anderson, Ruth A; McDaniel, Reuben R

    2010-02-01

    Data about health care organizations (HCOs) are not useful until they are interpreted. Such interpretations are influenced by the theoretical lenses used by the researcher. Our purpose was to suggest the usefulness of theories of complex adaptive systems (CASs) in guiding research interpretation. Specifically, we addressed two questions: (1) What are the implications for interpreting research observations in HCOs of the fact that we are observing relationships among diverse agents? (2) What are the implications for interpreting research observations in HCOs of the fact that we are observing relationships among agents that learn? We defined diversity and learning and the implications of the non-linear relationships among agents from a CAS perspective. We then identified some common analytical practices that were problematic and may lead to conceptual and methodological errors. Then we described strategies for interpreting the results of research observations. We suggest that the task of interpreting research observations of HCOs could be improved if researchers take into account that the systems they study are CASs with non-linear relationships among diverse, learning agents. Our analysis points out how interpretation of research results might be shaped by the fact that HCOs are CASs. We described how learning is, in fact, the result of interactions among diverse agents and that learning can, by itself, reduce or increase agent diversity. We encouraged researchers to be persistent in their attempts to reason about complex systems and learn to attend not only to structures, but also to processes and functions of complex systems.

  9. Commentary: Competency restoration research--complicating an already complex process.

    Science.gov (United States)

    Rotter, Merrill; Greenspan, Michael

    2011-01-01

    Predicting restorability in individuals found not competent to stand trial is an enduring focus of interest among forensic clinicians and academicians. In our commentary, we suggest that to understand this area even more comprehensively, we must look further. We must build on existing research on fitness to stand trial, move beyond diagnosis and a binary competence variable, and include the complex interplay between symptoms and fitness-related capacities that may be associated with lack of adjudicative competence and challenges to restorability.

  10. FoCa: a modular treatment planning system for proton radiotherapy with research and educational purposes.

    Science.gov (United States)

    Sánchez-Parcerisa, D; Kondrla, M; Shaindlin, A; Carabe, A

    2014-12-07

    FoCa is an in-house modular treatment planning system, developed entirely in MATLAB, which includes forward dose calculation of proton radiotherapy plans in both active and passive modalities as well as a generic optimization suite for inverse treatment planning. The software has a dual education and research purpose. From the educational point of view, it can be an invaluable teaching tool for educating medical physicists, showing the insights of a treatment planning system from a well-known and widely accessible software platform. From the research point of view, its current and potential uses range from the fast calculation of any physical, radiobiological or clinical quantity in a patient CT geometry, to the development of new treatment modalities not yet available in commercial treatment planning systems. The physical models in FoCa were compared with the commissioning data from our institution and show an excellent agreement in depth dose distributions and longitudinal and transversal fluence profiles for both passive scattering and active scanning modalities. 3D dose distributions in phantom and patient geometries were compared with a commercial treatment planning system, yielding a gamma-index pass rate of above 94% (using FoCa's most accurate algorithm) for all cases considered. Finally, the inverse treatment planning suite was used to produce the first prototype of intensity-modulated, passive-scattered proton therapy, using 13 passive scattering proton fields and multi-leaf modulation to produce a concave dose distribution on a cylindrical solid water phantom without any field-specific compensator.

  11. Real time capable control design with increased life expectancy for research purposes

    Science.gov (United States)

    Epple, S.; Jung, R.; Jalba, K.; Nasui, V.

    2017-05-01

    A new, freely programmable, scalable control system for academic research purposes was developed. The intention was, to have a control unit capable of handling multiple PT1000 temperature sensors at reasonable accuracy and temperature range, as well as digital input signals and providing more powerful output signals at 230V AC than conventional control units. To take full advantage of the system, control-loops are run in real time. The whole system runs independently of a personal computer. The two on-board RS232 connectors allow to connect further units to use more sensors or actuators or to connect other laboratory equipment, as required. To allow usage for long-time experiments, systematically electronic components with low failure-in-time (FIT) rate have been chosen in order to achieve high life expectancy. This paper describes the third prototype, which now provides stable measurements, and an improvement in accuracy compared to the previous designs. A rough estimation about the expected mean time between failures is given. As test case, a thermal solar system to produce hot tap water and assist heating in a single-family house was implemented. The solar fluid pump was power-controlled and several temperatures at different points in the hydraulic system were measured and used in the control algorithms. The hardware design proved suitable to test several different control strategies and their corresponding algorithms for the thermal solar system.

  12. An FPGA Scalable Software Defined Radio Platform Design for Educational and Research Purposes

    Directory of Open Access Journals (Sweden)

    Marcos Hervás

    2016-06-01

    Full Text Available In a digital modem design, the integration of the Analog to Digital Converters (ADC and Digital to Analog Converters (DAC with the core processor is usually a major issue for the designer. In this paper an FPGA scalable Software Defined Radio platform based on a Spartan-6 as a control unit is presented, developed for both educational and research purposes, which can fit the different application requirements in terms of analog front-end performance, processing unit and cost. The resolution and sampling frequency of the analog front-end are its main adjustable parameters. The processing core requirements involve the FPGA and the communication ports. A multidisciplinary working group was required to design a high performance system for both analog front-end and digital processing core in terms of signal integrity and electromagnetic compatibility. The platform has 5 different peripheral ports ranging from 16 kbps to 2.5 Gbps. The communication ports allow our students to develop a high range of applications for both on-site and online courses applying teaching methodology based on learning by doing using a real system to help them to reach other transversal skills.

  13. MYRRHA a multi-purpose hybrid research reactor for high-tech applications

    International Nuclear Information System (INIS)

    Abderrahim, H. A.; Baeten, P.

    2012-01-01

    MYRRHA (Multi-purpose hYbrid Research Reactor for High-tech Applications) is the flexible experimental accelerator driven system (ADS) in development at SCK-CEN. MYRRHA is able to work both in subcritical (ADS) as in critical mode. In this way, MYRRHA will allow fuel developments for innovative reactor systems, material developments for generation IV (GEN IV) systems, material developments for fusion reactors, radioisotope production and industrial applications, such as Si-doping. MYRRHA will also demonstrate the ADS full concept by coupling the three components (accelerator, spallation target and subcritical reactor) at reasonable power level to allow operation feedback, scalable to an industrial demonstrator and allow the study of efficient transmutation of high-level nuclear waste. MYRRHA is based on the heavy liquid metal technology and so it will contribute to the development of lead fast reactor (LFR) technology and in critical mode, MYRRHA will play the role of European technology pilot plant in the roadmap for LFR. In this paper the historical evolution of MYRRHA and the rationale behind the design choices is presented and the latest configuration of the reactor core and primary system is described. (authors)

  14. PANDA: a Large Scale Multi-Purpose Test Facility for LWR Safety Research

    Energy Technology Data Exchange (ETDEWEB)

    Dreier, Joerg; Paladino, Domenico; Huggenberger, Max; Andreani, Michele [Laboratory for Thermal-Hydraulics, Nuclear Energy and Safety Research Department, Paul Scherrer Institut (PSI), CH-5232 Villigen PSI (Switzerland); Yadigaroglu, George [ETH Zuerich, Technoparkstrasse 1, Einstein 22- CH-8005 Zuerich (Switzerland)

    2008-07-01

    PANDA is a large-scale multi-purpose thermal-hydraulics test facility, built and operated by PSI. Due to its modular structure, PANDA provides flexibility for a variety of applications, ranging from integral containment system investigations, primary system tests, component experiments to large-scale separate-effects tests. For many applications, the experimental results are directly used for example for concept demonstrations or for the characterisation of phenomena or components, but all the experimental data generated in the various test campaigns is unique and was or/and will still be widely used for the validation and improvement of a variety of computer codes, including codes with 3D capabilities, for reactor safety analysis. The paper provides an overview of the already completed and on-going research programs performed in the PANDA facility in the different area of applications, including the main results and conclusions of the investigations. In particular the advanced passive containment cooling system concept investigations of the SBWR, ESBWR as well as of the SWR1000 in relation to various aspects are presented and the main findings are summarised. Finally the goals, planned investigations and expected results of the on-going OECD project SETH-2 are presented. (authors)

  15. Cochlear Dummy Electrodes for Insertion Training and Research Purposes: Fabrication, Mechanical Characterization, and Experimental Validation

    Directory of Open Access Journals (Sweden)

    Jan-Philipp Kobler

    2015-01-01

    Full Text Available To develop skills sufficient for hearing preservation cochlear implant surgery, surgeons need to perform several electrode insertion trials in ex vivo temporal bones, thereby consuming relatively expensive electrode carriers. The objectives of this study were to evaluate the insertion characteristics of cochlear electrodes in a plastic scala tympani model and to fabricate radio opaque polymer filament dummy electrodes of equivalent mechanical properties. In addition, this study should aid the design and development of new cochlear electrodes. Automated insertion force measurement is a new technique to reproducibly analyze and evaluate the insertion dynamics and mechanical characteristics of an electrode. Mechanical properties of MED-EL’s FLEX28, FLEX24, and FLEX20 electrodes were assessed with the help of an automated insertion tool. Statistical analysis of the overall mechanical behavior of the electrodes and factors influencing the insertion force are discussed. Radio opaque dummy electrodes of comparable characteristics were fabricated based on insertion force measurements. The platinum-iridium wires were replaced by polymer filament to provide sufficient stiffness to the electrodes and to eradicate the metallic artifacts in X-ray and computed tomography (CT images. These low-cost dummy electrodes are cheap alternatives for surgical training and for in vitro, ex vivo, and in vivo research purposes.

  16. PANDA: a Large Scale Multi-Purpose Test Facility for LWR Safety Research

    International Nuclear Information System (INIS)

    Dreier, Joerg; Paladino, Domenico; Huggenberger, Max; Andreani, Michele; Yadigaroglu, George

    2008-01-01

    PANDA is a large-scale multi-purpose thermal-hydraulics test facility, built and operated by PSI. Due to its modular structure, PANDA provides flexibility for a variety of applications, ranging from integral containment system investigations, primary system tests, component experiments to large-scale separate-effects tests. For many applications, the experimental results are directly used for example for concept demonstrations or for the characterisation of phenomena or components, but all the experimental data generated in the various test campaigns is unique and was or/and will still be widely used for the validation and improvement of a variety of computer codes, including codes with 3D capabilities, for reactor safety analysis. The paper provides an overview of the already completed and on-going research programs performed in the PANDA facility in the different area of applications, including the main results and conclusions of the investigations. In particular the advanced passive containment cooling system concept investigations of the SBWR, ESBWR as well as of the SWR1000 in relation to various aspects are presented and the main findings are summarised. Finally the goals, planned investigations and expected results of the on-going OECD project SETH-2 are presented. (authors)

  17. Meta-analysis, complexity, and heterogeneity: a qualitative interview study of researchers' methodological values and practices.

    Science.gov (United States)

    Lorenc, Theo; Felix, Lambert; Petticrew, Mark; Melendez-Torres, G J; Thomas, James; Thomas, Sian; O'Mara-Eves, Alison; Richardson, Michelle

    2016-11-16

    Complex or heterogeneous data pose challenges for systematic review and meta-analysis. In recent years, a number of new methods have been developed to meet these challenges. This qualitative interview study aimed to understand researchers' understanding of complexity and heterogeneity and the factors which may influence the choices researchers make in synthesising complex data. We conducted interviews with a purposive sample of researchers (N = 19) working in systematic review or meta-analysis across a range of disciplines. We analysed data thematically using a framework approach. Participants reported using a broader range of methods and data types in complex reviews than in traditional reviews. A range of techniques are used to explore heterogeneity, but there is some debate about their validity, particularly when applied post hoc. Technical considerations of how to synthesise complex evidence cannot be isolated from questions of the goals and contexts of research. However, decisions about how to analyse data appear to be made in a largely informal way, drawing on tacit expertise, and their relation to these broader questions remains unclear.

  18. Embedding research in health systems: lessons from complexity theory.

    Science.gov (United States)

    Caffrey, Louise; Wolfe, Charles; McKevitt, Christopher

    2016-07-22

    Internationally, there has been increasing focus on creating health research systems. This article aims to investigate the challenges of implementing apparently simple strategies to support the development of a health research system. We focus on a case study of an English National Health Service Hospital Trust that sought to implement the national recommendation that health organisations should introduce a statement about research on all patient admission letters. We apply core concepts from complexity theory to the case study and undertake a documentary analysis of the email dialogue between staff involved in implementing this initiative. The process of implementing a research statement in patient admission letters in one clinical service took 1 year and 21 days. The length of time needed was influenced firstly by adaptive self-organisation, underpinned by competing interests. Secondly, it was influenced by the relationship between systems, rather than simply being a product of issues within those systems. The relationship between the health system and the research system was weaker than might have been expected. Responsibilities were unclear, leading to confusion and delayed action. Conventional ways of thinking about organisations suggest that change happens when leaders and managers change the strategic vision, structure or procedures in an organisation and then persuade others to rationally implement the strategy. However, health research systems are complex adaptive systems characterised by high levels of unpredictability due to self-organisation and systemic interactions, which give rise to 'emergent' properties. We argue for the need to study how micro-processes of organisational dynamics may give rise to macro patterns of behaviour and strategic organisational direction and for the use of systems approaches to investigate the emergent properties of health research systems.

  19. [Complex Trauma-related Disorders in Research and Practice].

    Science.gov (United States)

    Metzner, Franka; Pahlke, Stephanie; Diesing, Alice; Marin, Nina; Klasen, Fionna; Pawils, Silke; Schulte-Markwort, Michael; Richter-Appelt, Hertha

    2018-03-01

    Complex Trauma-related Disorders in Research and Practice Frequent traumata in childhood and adolescence are long-term or repeated interpersonal traumata caused by perpetrators in the close environment of the minors. For the description of the extensive symptoms after interpersonal Type II traumata, the complex trauma-related disorders Complex Posttraumatic Stress Disorder (CPTSD) or Disorder of Extreme Stress Not Otherwise Specified (DESNOS) and the Developmental Trauma Disorder (DTD) are being discussed for inclusion in the classification systems for mental disorders. Scientific knowledge and practical experiences regarding CPTSD, DESNOS and DTD in children and adolescents up to 18 years were examined by 1) a Systematic Review of 1,070 publications identified by database research and additional search strategies, and 2) a nationwide online survey of 374 psychotherapists and psychiatrists for children and adolescents in Germany. Of 13 included empirical studies (8 CPTSD or DESNOS, 5 DTD), 9 were conducted in the USA, 4 based on file coding and 3 on secondary data analysis and only 7 reported diagnosis rates (range: 0-78 %). Of the interviewed therapists, 100 % considered the CPTSD as being met with at least one patient with interpersonal traumata up to 18 years of age in 2014 and 99 % gave this estimate for the DTD. Two thirds of therapists rated the diagnostic option CPTSD and DTD as "very often" or "often" helpful for their therapeutic work with children and adolescents. While empirical data available is to be considered insufficient and characterized by methodological limitations, the relevance of complex trauma-related disorders is perceived as high by practitioners.

  20. Complexity and agent-based modelling in urban research

    DEFF Research Database (Denmark)

    Fertner, Christian

    influence on the bigger system. Traditional scientific methods or theories often tried to simplify, not accounting complex relations of actors and decision-making. The introduction of computers in simulation made new approaches in modelling, as for example agent-based modelling (ABM), possible, dealing......Urbanisation processes are results of a broad variety of actors or actor groups and their behaviour and decisions based on different experiences, knowledge, resources, values etc. The decisions done are often on a micro/individual level but resulting in macro/collective behaviour. In urban research...

  1. Research Strategy for Modeling the Complexities of Turbine Heat Transfer

    Science.gov (United States)

    Simoneau, Robert J.

    1996-01-01

    The subject of this paper is a NASA research program, known as the Coolant Flow Management Program, which focuses on the interaction between the internal coolant channel and the external film cooling of a turbine blade and/or vane in an aircraft gas turbine engine. The turbine gas path is really a very complex flow field. The combination of strong pressure gradients, abrupt geometry changes and intersecting surfaces, viscous forces, rotation, and unsteady blade/vane interactions all combine to offer a formidable challenge. To this, in the high pressure turbine, we add the necessity of film cooling. The ultimate goal of the turbine designer is to maintain or increase the high level of turbine performance and at the same time reduce the amount of coolant flow needed to achieve this end. Simply stated, coolant flow is a penalty on the cycle and reduces engine thermal efficiency. Accordingly, understanding the flow field and heat transfer associated with the coolant flow is a priority goal. It is important to understand both the film cooling and the internal coolant flow, particularly their interaction. Thus, the motivation for the Coolant Flow Management Program. The paper will begin with a brief discussion of the management and research strategy, will then proceed to discuss the current attack from the internal coolant side, and will conclude by looking at the film cooling effort - at all times keeping sight of the primary goal the interaction between the two. One of the themes of this paper is that complex heat transfer problems of this nature cannot be attacked by single researchers or even groups of researchers, each working alone. It truly needs the combined efforts of a well-coordinated team to make an impact. It is important to note that this is a government/industry/university team effort.

  2. Exotic plant species around Jeongeup Research Complex and RFT industrial complex

    International Nuclear Information System (INIS)

    Kim, Jin Kyu; Cha, Min Kyoung; Ryu, Tae Ho; Lee, Yun Jong; Kim, Jin Hong

    2015-01-01

    In Shinjeong-dong of Jeongeup, there are three government-supported research institutes and an RFT industrial complex which is currently being established. Increased human activities can affect flora and fauna as a man-made pressure onto the region. As a baseline study, status of exotic plants was investigated prior to a full operation of the RFT industrial complex. A total of 54 species and 1 variety of naturalized or introduced plants were found in the study area. Among them, three species (Ambrosia artemisifolia var. elatior, Rumex acetocella and Aster pilosus) belong to 'nuisance species', and four species (Phytolacca americana, Iopomoea hederacea, Ereechtites hieracifolia and Rudbeckia laciniata) to ‘monitor species’ designated by the ministry of Environment. Some of naturalized trees and plants were intentionally introduced in this area, while others naturally immigrated. Physalis angulata seems to immigrate in the study area in the form of mixture with animal feeds as its distribution coincided with the transportation route of the animal feeds. Liquidambar styraciflua is amenable to the ecological investigation on the possible expansion of the species to the nearby Naejang National Park as its leave shape and autumn color are very similar to those of maple trees. The number of naturalized plants around the RFT industrial complex will increase with an increase in floating population, in human activities in association with constructions of factories and operations of the complex. The result of this study provides baseline data for assessing the ecological change of the region according to the operation of the RFT industrial complex

  3. Exotic plant species around Jeongeup Research Complex and RFT industrial complex

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jin Kyu; Cha, Min Kyoung; Ryu, Tae Ho; Lee, Yun Jong; Kim, Jin Hong [Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup(Korea, Republic of)

    2015-08-15

    In Shinjeong-dong of Jeongeup, there are three government-supported research institutes and an RFT industrial complex which is currently being established. Increased human activities can affect flora and fauna as a man-made pressure onto the region. As a baseline study, status of exotic plants was investigated prior to a full operation of the RFT industrial complex. A total of 54 species and 1 variety of naturalized or introduced plants were found in the study area. Among them, three species (Ambrosia artemisifolia var. elatior, Rumex acetocella and Aster pilosus) belong to 'nuisance species', and four species (Phytolacca americana, Iopomoea hederacea, Ereechtites hieracifolia and Rudbeckia laciniata) to ‘monitor species’ designated by the ministry of Environment. Some of naturalized trees and plants were intentionally introduced in this area, while others naturally immigrated. Physalis angulata seems to immigrate in the study area in the form of mixture with animal feeds as its distribution coincided with the transportation route of the animal feeds. Liquidambar styraciflua is amenable to the ecological investigation on the possible expansion of the species to the nearby Naejang National Park as its leave shape and autumn color are very similar to those of maple trees. The number of naturalized plants around the RFT industrial complex will increase with an increase in floating population, in human activities in association with constructions of factories and operations of the complex. The result of this study provides baseline data for assessing the ecological change of the region according to the operation of the RFT industrial complex.

  4. A Time to Every Purpose: Understanding and Improving the Borrower Experience with Online Student Loan Entrance Counseling. Research Report

    Science.gov (United States)

    Fernandez, Chris

    2015-01-01

    Legally mandated student loan entrance counseling attempts to prepare first-time borrowers of federal student loans for this challenge; yet, researchers hypothesized that the online modules most borrowers use for this purpose have significant shortcomings. This report (the third in a series of five from TG Research) describes a study in which…

  5. "The Purpose of This Study Is to": Connecting Lexical Bundles and Moves in Research Article Introductions

    Science.gov (United States)

    Cortes, Viviana

    2013-01-01

    This article presents a group of lexical bundles identified in a corpus of research article introductions as the first step in the analysis of these expressions in the different sections of the research article. A one-million word corpus of research article introductions from various disciplines was compiled and the lexical bundles identified in…

  6. Introducing video recording in primary care midwifery for research purposes: procedure, dataset, and use.

    NARCIS (Netherlands)

    Spelten, E.R.; Martin, L.; Gitsels, J.T.; Pereboom, M.T.R.; Hutton, E.K.; Dulmen, S. van

    2015-01-01

    Background: video recording studies have been found to be complex; however very few studies describe the actual introduction and enrolment of the study, the resulting dataset and its interpretation. In this paper we describe the introduction and the use of video recordings of health care provider

  7. The ESPAT tool: a general-purpose DSS shell for solving stochastic optimization problems in complex river-aquifer systems

    Science.gov (United States)

    Macian-Sorribes, Hector; Pulido-Velazquez, Manuel; Tilmant, Amaury

    2015-04-01

    Stochastic programming methods are better suited to deal with the inherent uncertainty of inflow time series in water resource management. However, one of the most important hurdles in their use in practical implementations is the lack of generalized Decision Support System (DSS) shells, usually based on a deterministic approach. The purpose of this contribution is to present a general-purpose DSS shell, named Explicit Stochastic Programming Advanced Tool (ESPAT), able to build and solve stochastic programming problems for most water resource systems. It implements a hydro-economic approach, optimizing the total system benefits as the sum of the benefits obtained by each user. It has been coded using GAMS, and implements a Microsoft Excel interface with a GAMS-Excel link that allows the user to introduce the required data and recover the results. Therefore, no GAMS skills are required to run the program. The tool is divided into four modules according to its capabilities: 1) the ESPATR module, which performs stochastic optimization procedures in surface water systems using a Stochastic Dual Dynamic Programming (SDDP) approach; 2) the ESPAT_RA module, which optimizes coupled surface-groundwater systems using a modified SDDP approach; 3) the ESPAT_SDP module, capable of performing stochastic optimization procedures in small-size surface systems using a standard SDP approach; and 4) the ESPAT_DET module, which implements a deterministic programming procedure using non-linear programming, able to solve deterministic optimization problems in complex surface-groundwater river basins. The case study of the Mijares river basin (Spain) is used to illustrate the method. It consists in two reservoirs in series, one aquifer and four agricultural demand sites currently managed using historical (XIV century) rights, which give priority to the most traditional irrigation district over the XX century agricultural developments. Its size makes it possible to use either the SDP or

  8. The University-Academic Connection in Research: Corporate Purposes and Social Responsibilities.

    Science.gov (United States)

    David, Edward E., Jr.

    1982-01-01

    The growth of industry-supported research in universities is described, and ethical issues and the role of universities in commercial activities are debated. Industrial objectives, a comparison of some specific agreements, and desirable directions for industry support of university research are discussed. (MLW)

  9. Educational Research: Educational Purposes, the Nature of Knowledge and Ethical Issues

    Science.gov (United States)

    López-Alvarado, Julio

    2017-01-01

    Educational research should aim at improving educational practice by analysing the world of Education to understand it and make it better. It should be a critical, reflective and professionally oriented activity. Educational research should have three objectives: to explore issues and find answers to questions (for academics), to share policy…

  10. The popularisation of Positive Psychology as a defence against behavioural complexity in research and organisations

    Directory of Open Access Journals (Sweden)

    Frans Cilliers

    2010-12-01

    Research purpose: The aim of the study was to explore the systems psychodynamic nature of the manifesting defensive structures operating in Positive Psychology. Motivation for the study: The study investigated the popularity of Positive Psychology amongst academics, students and organisational consultants and the tendency to avoid the complexity of the relatedness between positive and negative as part of the human condition. Research design, approach and method: Qualitative research by means of a Listening Post was used, consisting of six psychologists in their roles as lecturers and organisational consultants. Thematic analyses led to the formulation of various working hypotheses, integrated into a research hypothesis. Main findings: Four themes manifested – namely, the manifesting defence mechanisms, a reluctance to relinquish positive psychology as an object of hope, a need to guard against being too hasty in breaking down positive psychology and a need for a psychology that can engage us in a conversation about integrating the complexities of the human condition. Practical/managerial implications: The findings were linked to Deo Strümpfer’s work, indicating that Positive Psychology originated in early 20th century psychology, which is indeed not about simplification, but is imbedded in the complexity of various behavioural continua. Contribution/value-add: Academics, students and organisational consultants are encouraged to revisit Strümpfer’s work to ensure that this psychology is appreciated for its depth and quality.

  11. Can qualitative and quantitative methods serve complementary purposes for policy research?

    OpenAIRE

    Maxwell, Daniel G.

    1998-01-01

    Qualitative and quantitative methods in social science research have long been separate spheres with little overlap. However, recent innovations have highlighted the complementarity of qualitative and quantitative approaches. The Accra Food and Nutrition Security Study was designed to incorporate the participation of a variety of constituencies in the research, and to rely on a variety of approaches — both qualitative and quantitative — to data collection and analysis. This paper reviews the ...

  12. RESEARCH OF PROBLEMS OF DESIGN OF COMPLEX TECHNICAL PROVIDING AND THE GENERALIZED MODEL OF THEIR DECISION

    Directory of Open Access Journals (Sweden)

    A. V. Skrypnikov

    2015-01-01

    Full Text Available Summary. In this work the general ideas of a method of V. I. Skurikhin taking into account the specified features develop and questions of the analysis and synthesis of a complex of technical means, with finishing them to the level suitable for use in engineering practice of design of information management systems are in more detail considered. In work the general system approach to the solution of questions of a choice of technical means of the information management system is created, the general technique of the sys tem analysis and synthesis of a complex of the technical means and its subsystems providing achievement of extreme value of criterion of efficiency of functioning of a technical complex of the information management system is developed. The main attention is paid to the applied party of system researches of complex technical providing, in particular, to definition of criteria of quality of functioning of a technical complex, development of methods of the analysis of information base of the information management system and definition of requirements to technical means, and also methods of structural synthesis of the main subsystems of complex technical providing. Thus, the purpose is research on the basis of system approach of complex technical providing the information management system and development of a number of methods of the analysis and the synthesis of complex technical providing suitable for use in engineering practice of design of systems. The well-known paradox of development of management information consists of that parameters of the system, and consequently, and requirements to the complex hardware, can not be strictly reasonable to development of algorithms and programs, and vice versa. The possible method of overcoming of these difficulties is prognostication of structure and parameters of complex hardware for certain management informations on the early stages of development, with subsequent clarification and

  13. How nature works complexity in interdisciplinary research and applications

    CERN Document Server

    Sanayei, Ali; Zenil, Hector; Rössler, Otto

    2014-01-01

    This book is based on the outcome of the “2012 Interdisciplinary Symposium on Complex Systems” held at the island of Kos.  The book consists of 12 selected papers of the symposium starting with a comprehensive overview and classification of complexity problems, continuing by chapters about complexity, its observation, modeling and its applications to solving various problems including real-life applications. More exactly, readers will have an encounter with the structural complexity of vortex flows, the use of chaotic dynamics within evolutionary algorithms, complexity in synthetic biology, types of complexity hidden inside evolutionary dynamics and possible controlling methods, complexity of rugged landscapes, and more. All selected papers represent innovative ideas, philosophical overviews and state-of-the-art discussions on aspects of complexity.  The book will be useful as instructional material for senior undergraduate and entry-level graduate students in computer science, physics, applied mathemat...

  14. From the Bronx to Bengifunda (and Other Lines of Flight): Deterritorializing Purposes and Methods in Science Education Research

    Science.gov (United States)

    Gough, Noel

    2011-01-01

    In this essay I explore a number of questions about purposes and methods in science education research prompted by my reading of Wesley Pitts' ethnographic study of interactions among four students and their teacher in a chemistry classroom in the Bronx, New York City. I commence three "lines of flight" (small acts of Deleuzo-Guattarian…

  15. Liquid Methane Conditioning Capabilities Developed at the NASA Glenn Research Center's Small Multi- Purpose Research Facility (SMiRF) for Accelerated Lunar Surface Storage Thermal Testing

    Science.gov (United States)

    Bamberger, Helmut H.; Robinson, R. Craig; Jurns, John M.; Grasl, Steven J.

    2011-01-01

    Glenn Research Center s Creek Road Cryogenic Complex, Small Multi-Purpose Research Facility (SMiRF) recently completed validation / checkout testing of a new liquid methane delivery system and liquid methane (LCH4) conditioning system. Facility checkout validation was conducted in preparation for a series of passive thermal control technology tests planned at SMiRF in FY10 using a flight-like propellant tank at simulated thermal environments from 140 to 350K. These tests will validate models and provide high quality data to support consideration of LCH4/LO2 propellant combination option for a lunar or planetary ascent stage.An infrastructure has been put in place which will support testing of large amounts of liquid methane at SMiRF. Extensive modifications were made to the test facility s existing liquid hydrogen system for compatibility with liquid methane. Also, a new liquid methane fluid conditioning system will enable liquid methane to be quickly densified (sub-cooled below normal boiling point) and to be quickly reheated to saturation conditions between 92 and 140 K. Fluid temperatures can be quickly adjusted to compress the overall test duration. A detailed trade study was conducted to determine an appropriate technique to liquid conditioning with regard to the SMiRF facility s existing infrastructure. In addition, a completely new roadable dewar has been procured for transportation and temporary storage of liquid methane. A new spherical, flight-representative tank has also been fabricated for integration into the vacuum chamber at SMiRF. The addition of this system to SMiRF marks the first time a large-scale liquid methane propellant test capability has been realized at Glenn.This work supports the Cryogenic Fluid Management Project being conducted under the auspices of the Exploration Technology Development Program, providing focused cryogenic fluid management technology efforts to support NASA s future robotic or human exploration missions.

  16. Using Computer Simulations of Negotiation for Educational and Research Purposes in Business Schools.

    Science.gov (United States)

    Conlon, Donald E.

    1989-01-01

    Discussion of educational and research advantages of using computer-based experimental simulations for the study of negotiation and dispute resolution in business schools focuses on two studies of undergraduates that used simulation exercises. The influence of time pressure on mediation is examined, and differences in student behavior are…

  17. The Dynamics of a General Purpose Technology in a Research and Assimilation Model

    NARCIS (Netherlands)

    Nahuis, R.

    1998-01-01

    Where is the productivity growth from the IT revolution? Why did the skill premium rise sharply in the early eighties? Were these phenomena related? This paper examines these questions in a general equilibrium model of growth. Technological progress in firms is driven by research aimed at improving

  18. Unpacking a Liturgical Framing of Desire for the Purposes of Educational Research

    Science.gov (United States)

    Renga, Ian Parker

    2017-01-01

    Much of the public discourse on education arguably reinforces the assumption that most stakeholders share the same desires for teaching and learning--desires reflecting a liberal paradigm that stresses individualism, control, and efficiency. But there are other desires, and additional empirical research informed by a Vygotskian sociocultural…

  19. Using newspaper collections in information institutions for research purposes: experiences of historians and linguists

    Directory of Open Access Journals (Sweden)

    Maja Krtalić

    2015-04-01

    Full Text Available The aim of this paper is to present the opinions, experiences and needs of a sample of scientists in the field of the humanities – namely historians and philologists – and their use of newspaper collections in memory institutions during scientific research. A part of the results gathered in the research, which was conducted within the Newspapers as a source of scientific information in social sciences and humanities project, and is presented here. This project examined the extent and practices in the use of newspapers as a resource of information for scientific research in the social sciences and humanities field in Croatia. The quantitative and qualitative data about the methods and level of use of newspaper material as a resource in scientific research were gathered. The results of this project implied that the newspapers are recognised and used as an admissible resource in scientific work, especially in the fields of history and philology. The fact that scientists have specific information needs and search patterns should be considered in creating innovative and effective digital newspaper collections.

  20. Comprehensive Assessment Systems: Purposes and Implementation. Research Watch. E&R Report No. 11.10

    Science.gov (United States)

    Troy, Talbot

    2011-01-01

    A comprehensive assessment system is one in which three types of assessments: summative, benchmark, and formative assessments are routinely administered to all students in K-12 classrooms. The first part of this report summarizes the research on comprehensive assessment systems and provides clarity in terms of how each individual assessment type…

  1. The Concept of Information Sharing Behaviors in Complex Organizations: Research in Latvian Enterprises

    Directory of Open Access Journals (Sweden)

    Andrejs Cekuls

    2016-12-01

    Full Text Available The purpose of this paper is to explore the factors influencing behaviors of information sharing in complex organizations. Evaluation of the previous studies on provision of information turnover process and the role of organizational culture in competitive intelligence of business environment in Latvia indicated the trends that employees of Latvian enterprises lack incentive to share information. Tasks of the study were to research the basis of the review of scientific sources and study aspects influencing habits of information sharing in complex organizations. For this particular study, the focus group is selected as the most appropriate data collection method for high-quality research. To find out individuals' opinions and attitudes two focus group discussions were carried out. Members from various industries and with different employment period were included in discussion groups. In aggregate, opinions of the employees from 41 different companies were summarized regarding the aspects affecting the process of information sharing in organizations. Results of researches show that that influence the sharing of information are closely related to the values: interpersonal trust, organizational trust, and organizational identification, support, fairness etc. Results of discussions showed that it is important for a manager to be aware of the factors affecting the performance of the organization. To identify the need for changes, a manager should follow events in the environment and analyze the extent, to which they affect the performance of the organization. Complexity science suggests that maturity to changes emerges when the system is far from balance, but the tension makes to accept changes.

  2. Recomendations concerning technical research and development with the purpose to industrially exploit marine algae

    Energy Technology Data Exchange (ETDEWEB)

    Hahn-Haegerdal, B.

    1980-10-01

    This report formulates a proposal for a program for technical research and development concerning use of Marine algae.The report is based on a retrospective literature search, an inquiry to potential algae users and producers in Sweden, visits to and correspondence with scientists and industries in Sweden and abroad. Technical research and development concerning marine algae is needed within the following fields: -Development of new sorts of algae offering resistance to parasite and disease adoptation to cultivation and har- vesting systems,and high-yielding concerning technically interesting components. -Development of suitable cultivation systems for Swedish conditions. -Co-cultivation of fish, mussels, oysters and crustaceans with algae. -Development of harvesting systems. -Methane rotting. -Fatty acid/hydrocarbon production as an alternative to methane rotting. -Physical-chemical properties of marine polysaccharides in relation to their technical properties. -Marine algae as fodder supplement.

  3. Will Women Diagnosed with Breast Cancer Provide Biological Samples for Research Purposes?

    Directory of Open Access Journals (Sweden)

    Shelley A Harris

    Full Text Available Little is known about the response rates for biological sample donation and attitudes towards control recruitment, especially in younger women. The goals of this pilot study were to determine in women recently diagnosed with breast cancer, the proportion of cases willing to provide biological samples and for purposes of control recruitment, contact information for friends or colleagues.A population-based sample of breast cancer cases (n = 417, 25-74 years was recruited from the Ontario Cancer Registry in 2010 and self-administered questionnaires were completed to determine willingness to provide samples (spot or 24-hr urine, saliva, blood and contact information for friends/colleagues for control recruitment. Using Χ2 analyses of contingency tables we evaluated if these proportions varied by age group (<45 and 45+ and other factors such as ethnicity, education, income, body mass index (BMI, smoking status and alcohol consumption.Cases were willing to provide blood samples, by visiting a clinic (62% or by having a nurse visit the home (61%. Moreover, they would provide saliva (73%, and morning or 24-hr urine samples (66% and 52%. Younger cases (≤45 were 3 times (OR more likely more than older cases to agree to collect morning urine (95% CI: 1.15-8.35. Only 26% of cases indicated they would provide contact information of friends or work colleagues to act as controls. Educated cases were more likely to agree to provide samples, and cases who consumed alcohol were more willing to provide contact information. Ethnicity, income, BMI and smoking had little effect on response rates.Reasonable response rates for biological sample collection should be expected in future case controls studies in younger women, but other methods of control selection must be devised.

  4. Managing complex research datasets using electronic tools: A meta-analysis exemplar

    Science.gov (United States)

    Brown, Sharon A.; Martin, Ellen E.; Garcia, Theresa J.; Winter, Mary A.; García, Alexandra A.; Brown, Adama; Cuevas, Heather E.; Sumlin, Lisa L.

    2013-01-01

    Meta-analyses of broad scope and complexity require investigators to organize many study documents and manage communication among several research staff. Commercially available electronic tools, e.g., EndNote, Adobe Acrobat Pro, Blackboard, Excel, and IBM SPSS Statistics (SPSS), are useful for organizing and tracking the meta-analytic process, as well as enhancing communication among research team members. The purpose of this paper is to describe the electronic processes we designed, using commercially available software, for an extensive quantitative model-testing meta-analysis we are conducting. Specific electronic tools improved the efficiency of (a) locating and screening studies, (b) screening and organizing studies and other project documents, (c) extracting data from primary studies, (d) checking data accuracy and analyses, and (e) communication among team members. The major limitation in designing and implementing a fully electronic system for meta-analysis was the requisite upfront time to: decide on which electronic tools to use, determine how these tools would be employed, develop clear guidelines for their use, and train members of the research team. The electronic process described here has been useful in streamlining the process of conducting this complex meta-analysis and enhancing communication and sharing documents among research team members. PMID:23681256

  5. Legal admissibility of tests with radiopharmaceuticals and with pharmaceuticals marked radioactive for research purposes

    International Nuclear Information System (INIS)

    Pabel, H.

    1976-01-01

    Presentation of the present and future legal position: 1) Tests with radiopharmaceuticals and marked medicine are absolutely necessary in the interest of the protection of the patient. 2) According to the valid radiation protection law such tests must be allowed. Restrictions can be decreed according to sect. 17 of the Atomic Energy Act. 3) According to sthe draft of the new Radiation Protection Ordinance, a licence may be refused in view of opposing primarily public interests. It is doubtful whether the rules provided in sect. 40 is covered by the autorizing standard. 4) The draft of a law for a reform of medicine law offers the possibility to issue detailed regulations on the testing of medicine. 5) The prohibition in sect. 7 of the medicine law also covers medicine, which is intended for experiments. The regulation according to sect. 7, however, admits release to hospitals and scientific research facilities. (orig./HP) [de

  6. Legal admissibility of tests with radiopharmaceuticals and with pharmaceuticals marked radioactive for research purposes

    International Nuclear Information System (INIS)

    Schultz, C.

    1976-01-01

    The drafts for governing experiments on human beings with radioactive marked pharmanceuticals, which exist in the Federal Republic of Germany and in Switzerland deal with fixing the principles of carrying out such tests- under consideration of the risks for the test person and the benifit for medical science and hence for the general public. They can be summarized as follows: 1) fixation of the maximum admissible radiation doses on the basis of the Radiation Protection Ordinance ; 2) development of a clearly fixed authorization obligation for each single research project and determination of those responsible therefor as well as supervision of the experiments and recording of the results; 3) limitation to the testing of medicaments; 4) improvement of the protection of the test person consent is a very important personal right, no legal substitution possible for persons partly incapable or incapable of exercising rights). (orig./HP) [de

  7. CORE SIM: A multi-purpose neutronic tool for research and education

    International Nuclear Information System (INIS)

    Demaziere, Christophe

    2011-01-01

    Highlights: → A highly flexible neutronic core simulator was developed. → The tool estimates the static neutron flux, the eigenmodes, and the neutron noise. → The tool was successfully validated via many benchmark cases. → The tool can be used for research and education. → The tool is freely available. - Abstract: This paper deals with the development, validation, and demonstration of an innovative neutronic tool. The novelty of the tool resides in its versatility, since many different systems can be investigated and different kinds of calculations can be performed. More precisely, both critical systems and subcritical systems with an external neutron source can be studied, and static and dynamic cases in the frequency domain (i.e. for stationary fluctuations) can be considered. In addition, the tool has the ability to determine the different eigenfunctions of any nuclear core. For each situation, the static neutron flux, the different eigenmodes and eigenvalues, the first-order neutron noise, and their adjoint functions are estimated, as well as the effective multiplication factor of the system. The main advantages of the tool, which is entirely MatLab based, lie with the robustness of the implemented numerical algorithms, its high portability between different computer platforms and operative systems, and finally its ease of use since no input deck writing is required. The present version of the tool, which is based on two-group diffusion theory, is mostly suited to investigate thermal systems. The definition of both the static and dynamic core configurations directly from the static macroscopic cross-sections and their fluctuations, respectively, makes the tool particularly well suited for research and education. Some of the many benchmark cases used to validate the tool are briefly reported. The static and dynamic capabilities of the tool are also demonstrated for the following configurations: a vibrating control rod, a perturbation traveling upwards

  8. Benchmark of physics design of a proposed 30 MW Multi Purpose Research Reactor using a Monte Carlo code MCNP

    International Nuclear Information System (INIS)

    Singh, Tej; Kumar, Jainendra; Sharma, Archana; Singh, Kanchhi; Raina, V.K.; Srinivasan, P.

    2009-01-01

    At present Dhruva and Cirus reactors provide majority of research reactor based experimental/irradiation facilities to cater to various needs of the vast pool of researchers in the field of sciences research and development work for nuclear power plants and production of radioisotopes. With a view to further consolidate and expand the scope of research and development in nuclear and allied sciences, a new 30 MWt Multi Purpose Research Reactor is proposed to be constructed. This paper describes some of the physics design features of this reactor using MCNP code to validate the deterministic methods. The criticality calculations for 100 material testing reactor (JHR) of France and 610 MW SAVANNAH thermal reactor were performed using MCNP computer codes to boost the confidence level in designing the physics design of reactor core. (author)

  9. Combined neutron activation analysis techniques for multiple purposes at Portuguese research reactor

    International Nuclear Information System (INIS)

    Dung, H.M.; Freitas, M.C.; Beasley, D.; Almeida, S.M.; Dionisio, I; Canha, N.H.; Galinha, C.; Marques, J.G.

    2010-01-01

    Full text: Developments of the neutron activation analysis (NAA) techniques using Compton suppression system (CSS), fast pneumatic irradiation facility (SIPRA), epithermal neutron and automatic sample changers (ASCs) associated with the traditional NAA for trace element determination in various sample types are described with reference to specific conditions at the 1 MW Portuguese research reactor (RPI). Experiences in application of k o -IAEA software for data processing in order to deduce the results are also discussed. A selected number of sample types which are intended to the application in biological and environmental areas as well as industrial and material samples are demonstrated which provide challenges in the irradiation, measurement and the interpretation of data to which in most cases a combined solution should be made. The role that each NAA technique can play in the combined scheme along with their optimized characteristics has been studied and shown. The combined NAA techniques at RPI established for on-going and potential projects as well as analysis service with respect to the element scope (48), typically Ag, Al, As, Au, Ba, Br, Ca, Cd, Ce, CI, Co, Cr, Cs, Cu, Dy, Er, Eu, F, Fe, Ga, Hf, Hg, I, In, K, La, Mg, Mn, Mo, Na, Rb, Sb, Sc, Se, Si, Sm, Sn, Sr, Ta, Tb, Th, Ti, U, V, W, Vb, Zn and Zr along with detection limits, accuracies and precision's have been evaluated as a trace analysis method meeting the requirements of the intended applications

  10. New and Old Aspects of Complexity in Modern Research

    CERN Document Server

    Musaev, Djamaladdin

    2012-01-01

    Complexity occurs in biological and synthetic systems alike.  This general phenomenon has been addressed in recent publications by investigators in disciplines ranging from chemistry and biology to psychology and philosophy.  Studies of complexity for molecular scientists have focussed on breaking symmetry, dissipative processes, and emergence.  Investigators in the social and medical sciences have focused on neurophenomenology, cognitive approaches and self-consciousness.  Complexity in both structure and function is inherent in many scientific disciplines of current significance and also in technologies of current importance that are rapidly evolving to address global societal needs.  Several of these multifaceted scientific disciplines are addressed in this book including complexity from the general and philosophical perspective, magnetic phenomena, control of self assembly and function in large multicomponent clusters, application of theory to probe structure and mechanism in highly complex molecular...

  11. 3D visualization of geo-scientific data for research and development purposes

    International Nuclear Information System (INIS)

    Mangeot, A.; Tabani, P.; Yven, B.; Dewonck, S.; Napier, B.; Waston, C.J.; Baker, G.R.; Shaw, R.P.

    2012-01-01

    Document available in extended abstract form only. In recent years national geoscience organizations have increasingly utilized 3D model data as an output to the stakeholder community. Advances in both software and hardware have led to an increasing use of 3D depictions of geoscience data alongside the standard 2D data formats such as maps and GIS data. By characterizing geoscience data in 3D, knowledge transfer between geo-scientists and stakeholders is improved as the mindset and thought processes are communicated more effectively in a 3D model than in a 2D flat file format. 3D models allow the user to understand the conceptual basis of the 2D data and aids the decision making process at local, regional and national scales. In April 29 2009 a Memorandum of Understanding has been signed between BGS and Andra in order to provide an improved mechanism for technical cooperation and collaboration in the Earth sciences. A specific agreement was signed the 1 December 2009 to evaluate the capacity of a 3D software called GeoVisionary to represent the Underground research Laboratory and its environment. GeoVisionary is the result of collaboration between Virtalis and the British Geological Survey. Combining a powerful data engine with a virtual geological tool-kit enables geo-scientists to visualize, analyze and share large datasets seamlessly in an immersive, real time environment A typical GeoVisionary environment contains one or more the following: 3D terrain files, Aerial photography, Bitmap overlays of specialized data, Vector shapes and outlines, 3D object Models. The key benefits are: Continuously stream geometry and photography in real time, Visualise 2D GIS data in immersive 3D stereo, Diverse datasets in a single environment, 'Fly' to any part of the data in seconds, Infinitely scalable, Prepare and evaluate before you begin fieldwork, Enhance team-working and increased efficiency of field operations, Clearer communication of results. Now, the 3D model has been

  12. Research and Measurement of Software Complexity Based on Wuli, Shili, Renli (WSR and Information Entropy

    Directory of Open Access Journals (Sweden)

    Rong Jiang

    2015-04-01

    Full Text Available Complexity is an important factor throughout the software life cycle. It is increasingly difficult to guarantee software quality, cost and development progress with the increase in complexity. Excessive complexity is one of the main reasons for the failure of software projects, so effective recognition, measurement and control of complexity becomes the key of project management. At first, this paper analyzes the current research situation of software complexity systematically and points out existing problems in current research. Then, it proposes a WSR framework of software complexity, which divides the complexity of software into three levels of Wuli (WL, Shili (SL and Renli (RL, so that the staff in different roles may have a better understanding of complexity. Man is the main source of complexity, but the current research focuses on WL complexity, and the research of RL complexity is extremely scarce, so this paper emphasizes the research of RL complexity of software projects. This paper not only analyzes the composing factors of RL complexity, but also provides the definition of RL complexity. Moreover, it puts forward a quantitative measurement method of the complexity of personnel organization hierarchy and the complexity of personnel communication information based on information entropy first and analyzes and validates the scientificity and rationality of this measurement method through a large number of cases.

  13. RESEARCH ON COMPLEX, LARGE INDUSTRIAL PROJECTS IN TRANSNATIONAL ENVIRONMENT

    Directory of Open Access Journals (Sweden)

    Florin POPESCU

    2016-12-01

    Full Text Available More and more projects from different industrial sectors developed in transnational environment are becoming more characterized as "complex". In recent years, there has been much discussion and controversy about the complexity of the projects, and, despite what has been written and said in various papers, journals and professional conferences, more confusion than clarification was created, complexity of projects being interpreted differently from one author to another. Most of the literature studied is based on linear, analytical and rational approach, focusing on the size of project management planning and control and actually less on projects that are characterized as taking place and grow into a dynamic socio-human environment in a continuous change. This study represents a critical review of existing theoretical models found in literature, highlighting their limitations. The output of this literature study represents an integration of different approaches concerning complexity under one umbrella to provide a common understanding of the evolution of this concept.

  14. The evaluation of complex interventions in palliative care: an exploration of the potential of case study research strategies.

    Science.gov (United States)

    Walshe, Catherine

    2011-12-01

    Complex, incrementally changing, context dependent and variable palliative care services are difficult to evaluate. Case study research strategies may have potential to contribute to evaluating such complex interventions, and to develop this field of evaluation research. This paper explores definitions of case study (as a unit of study, a process, and a product) and examines the features of case study research strategies which are thought to confer benefits for the evaluation of complex interventions in palliative care settings. Ten features of case study that are thought to be beneficial in evaluating complex interventions in palliative care are discussed, drawing from exemplars of research in this field. Important features are related to a longitudinal approach, triangulation, purposive instance selection, comprehensive approach, multiple data sources, flexibility, concurrent data collection and analysis, search for proving-disproving evidence, pattern matching techniques and an engaging narrative. The limitations of case study approaches are discussed including the potential for subjectivity and their complex, time consuming and potentially expensive nature. Case study research strategies have great potential in evaluating complex interventions in palliative care settings. Three key features need to be exploited to develop this field: case selection, longitudinal designs, and the use of rival hypotheses. In particular, case study should be used in situations where there is interplay and interdependency between the intervention and its context, such that it is difficult to define or find relevant comparisons.

  15. Process evaluation of complex interventions: Medical Research Council guidance

    OpenAIRE

    Moore, G.F.; Audrey, S.; Barker, M.; Bond, L.; Bonell, C.; Hardeman, W.; Moore, L.; O'Cathain, A.; Tinati, T.; Wight, D.; Baird, J.

    2015-01-01

    Attempts to tackle problems such as smoking and obesity increasingly use complex interventions. These are commonly defined as interventions that comprise multiple interacting components, although additional dimensions of complexity include the difficulty of their implementation and the number of organisational levels they target.1 Randomised controlled trials are regarded as the gold standard for establishing the effectiveness of interventions, when randomisation is feasible. However, effect ...

  16. Research and assessment of competitiveness of large engineering complexes

    Directory of Open Access Journals (Sweden)

    Krivorotov V.V.

    2017-01-01

    Full Text Available The urgency of the problem of ensuring the competitiveness of manufacturing and high-tech sectors is shown. Substantiated the decisive role of the large industrial complexes in the formation of the results of the national economy; the author’s interpretation of the concept of “industrial complex” with regard to current economic systems. Current approaches to assessing the competitiveness of enterprises and industrial complexes are analyzed; showing their main advantages and disadvantages. Provides scientific-methodological approach to the study and management of competitiveness of a large industrial complex; the description of its main units is provided. As a Central element of the scientific methodology approach proposed the methodology for assessing the competitiveness of a large industrial complex based on the Pattern-method; a modular system of indicators of competitiveness is developed and its adaptation to a large engineering complexes is made. Using the developed methodology the competitiveness of one of the largest engineering complexes of the group of companies Uralelectrotyazhmash, which is the leading enterprises in electrotechnical industry of Russia is assessed. The evaluation identified the main problems and bottlenecks in the development of these enterprises, and their comparison with leading competitors is provided. According to the results of the study the main conclusions and recommendations are formed.

  17. SOCIAL MEASUREMENT OF YOUTH’S HEALTH: DESIGNING OF INDICATORS OF COMPLEX SOCIOLOGICAL RESEARCH

    Directory of Open Access Journals (Sweden)

    Vitalii Valeriyevich Kulish

    2017-06-01

    Full Text Available Purpose. The article is devoted to solving the problem of social measurement of modern youth’s health. The subject of the analysis is the content of the concept, characteristics and indicators of the social health of young people, which enable using sociological research’ methods to measure a given status of the younger generation in contemporary Russian society. The purpose of this work is to define the theoretical and methodological foundations of the sociological analysis of the young people social health and to substantiate its main indicators in the tools of complex sociological research. Methodology of the study. The basis of the research is formed by the system approach, the complex approach, the logical-conceptual method and general scientific methods of research: comparative analysis, system analysis, construction of social indicators, modeling. Results. The social health of young people is defined through the category “status” and is considered as an integrated indicator of the social quality of the younger generation. It is substantiated that the social health of youth is a status of socio-demographic community in which it is able not only to adapt to the changing conditions of the social environment but is also ready to transform actively the surrounding reality, having the potential to resist destructive social phenomena and processes. The main indicators that allow measuring the social health of young people by sociological methods are determined: adaptability in the social environment, social activity in all spheres of public life, social orientation and significance of activity, behavior regulativity by social norms and universal values, creativity of thinking and behavior, readiness for social integration and self-development. A system of social indicators and indicators for conducting a sociological study of social health in historical memory, value orientations and everyday practices of young people has been developed.

  18. The high flux reactor Petten, A multi-purpose research and test facility for the future of nuclear energy

    International Nuclear Information System (INIS)

    Bergmans, H.; Duijves, K.; Conrad, R.; Markgraf, J.F.W.; May, R.; Moss, R.L.; Sordon, G.; Tartaglia, G.P.

    1996-01-01

    The High Flux Reactor (HFR) at Petten, is owned by the European Commission (EC) and managed by the Institute for Advanced Materials (IAM) of the Joint Research Centre (JRC) of the EC. Its operation has been entrusted since 1962 to the Netherlands Energy Research Foundation (ECN). The HFR is one of the most powerful multi-purpose research and test reactors in the world. Together with the ECN hot cells at Petten, it has provided since three decades an integral and full complement of irradiation and examination services as required by current and future research and development for nuclear energy, industry and research organizations. Since 1963, the HFR has recognized record of consistent, reliable and high availability of more than 250 days of operation per year. The HFR has 20 in-core and 12 poolside irradiation positions, plus 12 beam tubes. With a variety of dedicated irradiation devices, and with its long-standing experience in executing small and large irradiation projects, the HFR is particularly suited for fuel, materials and components testing for all reactor lines, including thermonuclear fusion reactors. In addition, processing with neutrons and gamma rays, neutron-based research and inspection services are employed by industry and research, such as activation analysis, boron neutron capture therapy, neutron radiography and neutron diffraction. Moreover, in recent years, HFRs' mission has been broadened within the area of radioisotopes production, where, within a few years, the HFR has attained the European leadership in production volume

  19. Cumulative complexity: a functional, patient-centered model of patient complexity can improve research and practice.

    Science.gov (United States)

    Shippee, Nathan D; Shah, Nilay D; May, Carl R; Mair, Frances S; Montori, Victor M

    2012-10-01

    To design a functional, patient-centered model of patient complexity with practical applicability to analytic design and clinical practice. Existing literature on patient complexity has mainly identified its components descriptively and in isolation, lacking clarity as to their combined functions in disrupting care or to how complexity changes over time. The authors developed a cumulative complexity model, which integrates existing literature and emphasizes how clinical and social factors accumulate and interact to complicate patient care. A narrative literature review is used to explicate the model. The model emphasizes a core, patient-level mechanism whereby complicating factors impact care and outcomes: the balance between patient workload of demands and patient capacity to address demands. Workload encompasses the demands on the patient's time and energy, including demands of treatment, self-care, and life in general. Capacity concerns ability to handle work (e.g., functional morbidity, financial/social resources, literacy). Workload-capacity imbalances comprise the mechanism driving patient complexity. Treatment and illness burdens serve as feedback loops, linking negative outcomes to further imbalances, such that complexity may accumulate over time. With its components largely supported by existing literature, the model has implications for analytic design, clinical epidemiology, and clinical practice. Copyright © 2012 Elsevier Inc. All rights reserved.

  20. Modeling Complex Nesting Structures in International Business Research

    DEFF Research Database (Denmark)

    Nielsen, Bo Bernhard; Nielsen, Sabina

    2013-01-01

    hierarchical random coefficient models (RCM) are often used for the analysis of multilevel phenomena, IB issues often result in more complex nested structures. This paper illustrates how cross-nested multilevel modeling allowing for predictor variables and cross-level interactions at multiple (crossed) levels...

  1. Structure, Agency, Complexity Theory and Interdisciplinary Research in Education Studies

    Science.gov (United States)

    Smith, John A.

    2013-01-01

    This article argues that Education Studies needs to develop its existing interdisciplinarity understanding of structures and agencies by giving greater attention to the modern process theories of self-organisation in the physical, biological, psychological and social sciences, sometimes given the umbrella term "complexity theory". The…

  2. Young people's views about the purpose and composition of research ethics committees: findings from the PEARL qualitative study.

    Science.gov (United States)

    Audrey, Suzanne; Brown, Lindsey; Campbell, Rona; Boyd, Andy; Macleod, John

    2016-09-02

    Avon Longitudinal Study of Parents and Children (ALSPAC) is a birth cohort study within which the Project to Enhance ALSPAC through Record Linkage (PEARL) was established to enrich the ALSPAC resource through linkage between ALSPAC participants and routine sources of health and social data. PEARL incorporated qualitative research to seek the views of young people about data linkage, including their opinions about appropriate safeguards and research governance. In this paper we focus on views expressed about the purpose and composition of research ethics committees. Digitally recorded interviews were conducted with 48 participants aged 17-19 years. Participants were asked about whether medical research should be monitored and controlled, their knowledge of research ethics committees, who should sit on these committees and what their role should be. Interview recordings were fully transcribed and anonymised. Thematic analysis was undertaken, assisted by the Framework approach to data management. The majority of interviewees had little or no specific knowledge of ethics committees. Once given basic information about research ethics committees, only three respondents suggested there was no need for such bodies to scrutinise research. The key tasks of ethics committees were identified as monitoring the research process and protecting research participants. The difficulty of balancing the potential to inhibit research against the need to protect research participants was acknowledged. The importance of relevant research and professional expertise was identified but it was also considered important to represent wider public opinion, and to counter the bias potentially associated with self-selection possibly through a selection process similar to 'jury duty'. There is a need for more education and public awareness about the role and composition of research ethics committees. Despite an initial lack of knowledge, interviewees were able to contribute their ideas and balance

  3. Adopting the Transformational Leadership Perspective in a Complex Research Environment

    Science.gov (United States)

    Atkinson, Timothy N.; Pilgreen, Tom

    2011-01-01

    Transformational Leadership is a popular topic among leadership scholars, but for research administrators, Transformational Leadership might seem like an enigmatic approach given its various contexts. Research administrators might think the transformational approach is only for executives, or that they do not have enough staff to call themselves…

  4. Data Mining: A Hybrid Methodology for Complex and Dynamic Research

    Science.gov (United States)

    Lang, Susan; Baehr, Craig

    2012-01-01

    This article provides an overview of the ways in which data and text mining have potential as research methodologies in composition studies. It introduces data mining in the context of the field of composition studies and discusses ways in which this methodology can complement and extend our existing research practices by blending the best of what…

  5. The Challenge of Researching Violent Societies: Navigating Complexities in Ethnography

    Science.gov (United States)

    Tshabangu, Icarbord

    2009-01-01

    Through use of a recent study researching democratic education and citizenship in Zimbabwe, this paper examines the methodological dilemmas and challenges faced by an ethnographer, particularly by a research student in a violent context. The article posits a bricolage strategy to navigate some of the dangers and methodological dilemmas inherent so…

  6. The Wide and Complex Field of NAFLD Biomarker Research: Trends

    OpenAIRE

    Wichro, Erika; Macheiner, Tanja; Schmid, Jasmin; Kavsek, Barbara; Sargsyan, Karine

    2014-01-01

    Background. Nonalcoholic fatty liver disease is now acknowledged as a complex public health issue linked to sedentary lifestyle, obesity, and related disorders like type 2 diabetes and metabolic syndrome. Aims. We aimed to retrieve its trends out of the huge amount of published data. Therefore, we conducted an extensive literature search to identify possible biomarker and/or biomarker combinations by retrospectively assessing and evaluating common and novel biomarkers to predict progression a...

  7. Research of complex briquetted modifiers influence on cast iron properties

    Directory of Open Access Journals (Sweden)

    Наталя Валеріївна Сусло

    2016-07-01

    Full Text Available Such properties of cast iron as hardness and shock resistance are relevant and have been investigated. Some possible ways to improve these properties have been studied and solutions to the assigned tasks in accordance with modern trends have been found. The use of nano-dispersed modifiers is most promising in modification. The compositions of experimental complex briquetted modifiers have been developed. The technology of cast iron processing with complex briquetted modifiers has been developed. A series of experiments on the effect of a complex briquetted modifier introduced into cast iron on its properties were carried out. The rational content of components in the briquette that makes maximum use of the modifying effect and improves such service characteristics of cast iron as hardness, impact - and wear-resistance has been defined. Ways of a briquette destruction in metal have been explored. The effect of an organic binder amount on the destruction of a briquette and its dissolution in the melt has been investigated. Rational composition of the briquetted modifier that makes it possible to increase hardness and impact resistance of cast iron has been developed

  8. A call for a multifaceted approach to language learning motivation research: Combining complexity, humanistic, and critical perspectives

    Directory of Open Access Journals (Sweden)

    Julian Pigott

    2012-10-01

    Full Text Available In this paper I give an overview of recent developments in the L2 motivation field, in particular the movement away from quantitative, questionnaire-based methodologies toward smaller-scale qualitative studies incorporating concepts from complexity theory. While complexity theory provides useful concepts for exploring motivation in new ways, it has nothing to say about ethics, morality, ideology, politics, power or educational purpose. Furthermore, calls for its use come primarily from researchers from the quantitative tradition whose aim in importing this paradigm from the physical sciences appears to be to conceptualize and model motivation more accurately. The endeavor therefore remains a fundamentally positivist one. Rather than being embraced as a self-contained methodology, I argue that complexity theory should be used cautiously and prudently alongside methods grounded in other philosophical traditions. Possibilities abound, but here I suggest one possible multifaceted approach combining complexity theory, a humanisticconception of motivation, and a critical perspective.

  9. Experimental complex for high flux-materials interaction research

    International Nuclear Information System (INIS)

    Gagen-Torn, V.K.; Kirillov, I.R.; Komarov, V.L.; Litunovsky, V.N.; Mazul, I.V.; Ovchinnikov, I.B.; Prokofjev, Yu.G.; Saksagansky, G.L.; Titov, V.A.

    1995-01-01

    The experimental complex for high heat flux testing of divertor materials and bumper mock-ups under conditions close to both ITER stationary and plasma disruption PFC heat loads is described. High power plasma and electron beams are using as high heat flux sources. The former are applied to disruption simulation experiments. The values of pulsed plasma heat flux load up to 110 MJ/m 2 and stationary e-beam load up to 15 MW/m 2 can obtained on these facilities. (orig.)

  10. RESEARCH OF PHENOLIC COMPLEX OF LEAVES OF MESPILUS GERMANICA L.

    Directory of Open Access Journals (Sweden)

    N. N. Vdovenko-Martynova

    2014-01-01

    Full Text Available Leaves of Mespilus germanica L. from Rosaceae family gathered in Kabardino Balkaria regions and in Botanical garden of Pyatigorsk Medical and Pharmaceutical Institute. The purpose of the study is examination of phenolic compounds in the raw materieals under analysis. Qualitative composition and quantitative identification of phenolic compounds in the air-dry raw materials of samples under study was done using qualitative reactions and high performance liquid chromatography method (HPLC. 13 compounds were received, 8 of them were identified as the substances of phenolic origin: flavonoids (quercetine, taxofolin, luteolin, hydroxycoric acids (gallic, chlorogenic, ferulic, polyphenolic compounds (epigallocatechin gallate, epicatechin. The sum of identified phenolic compounds amounted to 78,24% of all compounds found by the given method.

  11. Methods for researching intercultural communication in globalized complex societies

    DEFF Research Database (Denmark)

    Jensen, Iben; Andreasen, Lars Birch

    2014-01-01

    The field of intercultural communication research is challenged theoretically as well as methodologically by global changes such as migration, global mobility, mass media, tourism, etc. According to these changes cultures can no longer be seen as national entities, and cultural identity can...

  12. The ethics of good communication in a complex research partnership.

    Science.gov (United States)

    Sodeke, Stephen; Turner, Timothy; Tarver, Will

    2010-08-01

    The tripartite partnership among Morehouse School of Medicine, Tuskegee University, and University of Alabama at Birmingham is complex. In 2005, the three schools--with different institutional cultures, characters, and resources--agreed to collaborate in efforts to eliminate racial/ethnic disparities in cancer burdens. Pursuing this laudable aim predictably involved some miscommunication. The Bioethics Shared Resource (BSR) group foresaw such challenges and monitored interactions to prevent harm, noting that while effective communication is critical to the achievement of mutual goals, an understanding and prudent use of proven communication principles is a sine qua non for success. In this commentary, we share the undergirding moral concepts, communication approaches, and lessons learned. This experience has led us to propose an ethics of good communication for others to consider.

  13. The Wide and Complex Field of NAFLD Biomarker Research: Trends.

    Science.gov (United States)

    Wichro, Erika; Macheiner, Tanja; Schmid, Jasmin; Kavsek, Barbara; Sargsyan, Karine

    2014-01-01

    Background. Nonalcoholic fatty liver disease is now acknowledged as a complex public health issue linked to sedentary lifestyle, obesity, and related disorders like type 2 diabetes and metabolic syndrome. Aims. We aimed to retrieve its trends out of the huge amount of published data. Therefore, we conducted an extensive literature search to identify possible biomarker and/or biomarker combinations by retrospectively assessing and evaluating common and novel biomarkers to predict progression and prognosis of obesity related liver diseases. Methodology. We analyzed finally 62 articles accounting for 157 cohorts and 45,288 subjects. Results. Despite the various approaches, most cohorts were considerably small and rarely comparable. Also, we found that the same standard parameters were measured rather than novel biomarkers. Diagnostics approaches appeared incomparable. Conclusions. Further collaborative investigations on harmonizing ways of data acquisition and identifying such biomarkers for clinical use are necessary to yield sufficient significant results of potential biomarkers.

  14. Dermal tumorigen PAH and complex mixtures for biological research

    International Nuclear Information System (INIS)

    Griest, W.H.; Guerin, M.R.; Ho, C.

    1985-01-01

    Thirteen commercially available, commonly reported four-five ring dermal tumorigen PAHs, were determined in a set of complex mixtures consisting of crude and upgraded coal liquids, and petroleum crude oils and their distillate fractions. Semi-preparative scale, normal phase high performance liquid chromatographic fractionation followed by capillary column gas chromatography or gas chromatography-mass spectroscopy were used for the measurements. Deuterated or carbon-14 labeled PAH served as internal standards or allowed recovery corrections. Approaches for the preparation and measurement of radiolabeled PAH were examined to provide chemical probes for biological study. Synthetic routes for production of 14 C labeled dihydrobenzo[a]pyrene and 14 C- or 3 H 10-azabenzo[a]pyrene are being studied to provide tracers for fundamental studies in tracheal transplant and skin penetration systems. (DT)

  15. Research on Evolutionary Mechanism of Agile Supply Chain Network via Complex Network Theory

    Directory of Open Access Journals (Sweden)

    Nai-Ru Xu

    2016-01-01

    Full Text Available The paper establishes the evolutionary mechanism model of agile supply chain network by means of complex network theory which can be used to describe the growth process of the agile supply chain network and analyze the complexity of the agile supply chain network. After introducing the process and the suitability of taking complex network theory into supply chain network research, the paper applies complex network theory into the agile supply chain network research, analyzes the complexity of agile supply chain network, presents the evolutionary mechanism of agile supply chain network based on complex network theory, and uses Matlab to simulate degree distribution, average path length, clustering coefficient, and node betweenness. Simulation results show that the evolution result displays the scale-free property. It lays the foundations of further research on agile supply chain network based on complex network theory.

  16. Design and implementation progress of multi-purpose simulator for nuclear research reactor using LabVIEW

    International Nuclear Information System (INIS)

    Arafa, Amany Abdel Aziz; Saleh, Hassan Ibrahim; Ashoub, Nagieb

    2015-01-01

    This paper illustrates the neutronic and thermal hydraulic models that were implemented in the nuclear research reactor simulator based on LabVIEW. It also describes the system and transient analysis of the simulator that takes into consideration the temperature effects and poisoning. This simulator is designed to be a multi-purpose in which the operator could understand the effects of the input parameters on the reactor. A designer can study different solutions for virtual reactor accident scenarios. The main features of the simulator are the flexibility to design and maintain the interface and the ability to redesign and remodel the reactor core engine. The developed reactor simulator permits to acquire hands-on the experience of the physics and technology of nuclear reactors including reactivity control, thermodynamics, technology design and safety system design. This simulator can be easily customizable and upgradable and new opportunities for collaboration between academic groups could be conducted.

  17. Design and implementation progress of multi-purpose simulator for nuclear research reactor using LabVIEW

    Energy Technology Data Exchange (ETDEWEB)

    Arafa, Amany Abdel Aziz; Saleh, Hassan Ibrahim [Atomic Energy Authority, Cairo (Egypt). Radiation Engineering Dept.; Ashoub, Nagieb [Atomic Energy Authority, Cairo (Egypt). Nuclear Research Center

    2015-11-15

    This paper illustrates the neutronic and thermal hydraulic models that were implemented in the nuclear research reactor simulator based on LabVIEW. It also describes the system and transient analysis of the simulator that takes into consideration the temperature effects and poisoning. This simulator is designed to be a multi-purpose in which the operator could understand the effects of the input parameters on the reactor. A designer can study different solutions for virtual reactor accident scenarios. The main features of the simulator are the flexibility to design and maintain the interface and the ability to redesign and remodel the reactor core engine. The developed reactor simulator permits to acquire hands-on the experience of the physics and technology of nuclear reactors including reactivity control, thermodynamics, technology design and safety system design. This simulator can be easily customizable and upgradable and new opportunities for collaboration between academic groups could be conducted.

  18. Recommended Research Directions for Improving the Validation of Complex Systems Models.

    Energy Technology Data Exchange (ETDEWEB)

    Vugrin, Eric D. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Trucano, Timothy G. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Swiler, Laura Painton [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Finley, Patrick D. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Flanagan, Tatiana Paz [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Naugle, Asmeret Bier [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Tsao, Jeffrey Y. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Verzi, Stephen Joseph [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-02-01

    Improved validation for models of complex systems has been a primary focus over the past year for the Resilience in Complex Systems Research Challenge. This document describes a set of research directions that are the result of distilling those ideas into three categories of research -- epistemic uncertainty, strong tests, and value of information. The content of this document can be used to transmit valuable information to future research activities, update the Resilience in Complex Systems Research Challenge's roadmap, inform the upcoming FY18 Laboratory Directed Research and Development (LDRD) call and research proposals, and facilitate collaborations between Sandia and external organizations. The recommended research directions can provide topics for collaborative research, development of proposals, workshops, and other opportunities.

  19. Dynamics of Research Team Formation in Complex Networks

    Science.gov (United States)

    Sun, Caihong; Wan, Yuzi; Chen, Yu

    Most organizations encourage the formation of teams to accomplish complicated tasks, and vice verse, effective teams could bring lots benefits and profits for organizations. Network structure plays an important role in forming teams. In this paper, we specifically study the dynamics of team formation in large research communities in which knowledge of individuals plays an important role on team performance and individual utility. An agent-based model is proposed, in which heterogeneous agents from research communities are described and empirically tested. Each agent has a knowledge endowment and a preference for both income and leisure. Agents provide a variable input (‘effort’) and their knowledge endowments to production. They could learn from others in their team and those who are not in their team but have private connections in community to adjust their own knowledge endowment. They are allowed to join other teams or work alone when it is welfare maximizing to do so. Various simulation experiments are conducted to examine the impacts of network topology, knowledge diffusion among community network, and team output sharing mechanisms on the dynamics of team formation.

  20. 1992 annual report on scientific programs: A broad research program on the sciences of complexity

    Energy Technology Data Exchange (ETDEWEB)

    1992-12-31

    In 1992 the Santa Fe Institute hosted more than 100 short- and long-term research visitors who conducted a total of 212 person-months of residential research in complex systems. To date this 1992 work has resulted in more than 50 SFI Working Papers and nearly 150 publications in the scientific literature. The Institute`s book series in the sciences of complexity continues to grow, now numbering more than 20 volumes. The fifth annual complex systems summer school brought nearly 60 graduate students and postdoctoral fellows to Santa Fe for an intensive introduction to the field. Research on complex systems-the focus of work at SFI-involves an extraordinary range of topics normally studied in seemingly disparate fields. Natural systems displaying complex adaptive behavior range upwards from DNA through cells and evolutionary systems to human societies. Research models exhibiting complex behavior include spin glasses, cellular automata, and genetic algorithms. Some of the major questions facing complex systems researchers are: (1) explaining how complexity arises from the nonlinear interaction of simple components; (2) describing the mechanisms underlying high-level aggregate behavior of complex systems (such as the overt behavior of an organism, the flow of energy in an ecology, the GNP of an economy); and (3) creating a theoretical framework to enable predictions about the likely behavior of such systems in various conditions.

  1. Moving Virtual Research Environments from high maintenance Stovepipes to Multi-purpose Sustainable Service-oriented Science Platforms

    Science.gov (United States)

    Klump, Jens; Fraser, Ryan; Wyborn, Lesley; Friedrich, Carsten; Squire, Geoffrey; Barker, Michelle; Moloney, Glenn

    2017-04-01

    The researcher of today is likely to be part of a team distributed over multiple sites that will access data from an external repository and then process the data on a public or private cloud or even on a large centralised supercomputer. They are increasingly likely to use a mixture of their own code, third party software and libraries, or even access global community codes. These components will be connected into a Virtual Research Environments (VREs) that will enable members of the research team who are not co-located to actively work together at various scales to share data, models, tools, software, workflows, best practices, infrastructures, etc. Many VRE's are built in isolation: designed to meet a specific research program with components tightly coupled and not capable of being repurposed for other use cases - they are becoming 'stovepipes'. The limited number of users of some VREs also means that the cost of maintenance per researcher can be unacceptably high. The alternative is to develop service-oriented Science Platforms that enable multiple communities to develop specialised solutions for specific research programs. The platforms can offer access to data, software tools and processing infrastructures (cloud, supercomputers) through globally distributed, interconnected modules. In Australia, the Virtual Geophysics Laboratory (VGL) was initially built to enable a specific set of researchers in government agencies access to specific data sets and a limited number of tools, that is now rapidly evolving into a multi-purpose Earth science platform with access to an increased variety of data, a broader range of tools, users from more sectors and a diversity of computational infrastructures. The expansion has been relatively easy, because of the architecture whereby data, tools and compute resources are loosely coupled via interfaces that are built on international standards and accessed as services wherever possible. In recent years, investments in

  2. Legal and security requirements for the air transportation of cyanotoxins and toxigenic cyanobacterial cells for legitimate research and analytical purposes.

    Science.gov (United States)

    Metcalf, J S; Meriluoto, J A O; Codd, G A

    2006-05-25

    Cyanotoxins are now recognised by international and national health and environment agencies as significant health hazards. These toxins, and the cells which produce them, are also vulnerable to exploitation for illegitimate purposes. Cyanotoxins are increasingly being subjected to national and international guidelines and regulations governing their production, storage, packaging and transportation. In all of these respects, cyanotoxins are coming under the types of controls imposed on a wide range of chemicals and other biotoxins of microbial, plant and animal origin. These controls apply whether cyanotoxins are supplied on a commercial basis, or stored and transported in non-commercial research collaborations and programmes. Included are requirements concerning the transportation of these toxins as documented by the United Nations, the International Air Transport Association (IATA) and national government regulations. The transportation regulations for "dangerous goods", which by definition include cyanotoxins, cover air mail, air freight, and goods checked in and carried on flights. Substances include those of determined toxicity and others of suspected or undetermined toxicity, covering purified cyanotoxins, cyanotoxin-producing laboratory strains and environmental samples of cyanobacteria. Implications of the regulations for the packaging and air-transport of dangerous goods, as they apply to cyanotoxins and toxigenic cyanobacteria, are discussed.

  3. Cell line with endogenous EGFRvIII expression is a suitable model for research and drug development purposes.

    Science.gov (United States)

    Stec, Wojciech J; Rosiak, Kamila; Siejka, Paulina; Peciak, Joanna; Popeda, Marta; Banaszczyk, Mateusz; Pawlowska, Roza; Treda, Cezary; Hulas-Bigoszewska, Krystyna; Piaskowski, Sylwester; Stoczynska-Fidelus, Ewelina; Rieske, Piotr

    2016-05-31

    Glioblastoma is the most common and malignant brain tumor, characterized by high cellular heterogeneity. About 50% of glioblastomas are positive for EGFR amplification, half of which express accompanying EGFR mutation, encoding truncated and constitutively active receptor termed EGFRvIII. Currently, no cell models suitable for development of EGFRvIII-targeting drugs exist, while the available ones lack the intratumoral heterogeneity or extrachromosomal nature of EGFRvIII.The reports regarding the biology of EGFRvIII expressed in the stable cell lines are often contradictory in observations and conclusions. In the present study, we use DK-MG cell line carrying endogenous non-modified EGFRvIII amplicons and derive a sub-line that is near depleted of amplicons, whilst remaining identical on the chromosomal level. By direct comparison of the two lines, we demonstrate positive effects of EGFRvIII on cell invasiveness and populational growth as a result of elevated cell survival but not proliferation rate. Investigation of the PI3K/Akt indicated no differences between the lines, whilst NFκB pathway was over-active in the line strongly expressing EGFRvIII, finding further supported by the effects of NFκB pathway specific inhibitors. Taken together, these results confirm the important role of EGFRvIII in intrinsic and extrinsic regulation of tumor behavior. Moreover, the proposed models are stable, making them suitable for research purposes as well as drug development process utilizing high throughput approach.

  4. A Multidisciplinary Delphi Consensus-Based Checklist to Define Clinical Documentation Tools for Both Routine and Research Purposes

    Directory of Open Access Journals (Sweden)

    Cecilia Veraar

    2018-01-01

    Full Text Available Background: To the best of our knowledge, a strategic approach to define the contents of structured clinical documentation tools for both clinical routine patient care and research purposes has not been reported so far, although electronic health record will become more and more structured and detailed in the future. Objective: To achieve an interdisciplinary consensus on a checklist to be considered for the preparation of disease- and situation-specific clinical documentation tools. Methods: A 2-round Delphi consensus-based process was conducted both with 19 physicians of different disciplines and 14 students from Austria, Switzerland, and Germany. Agreement was defined as 80% or more positive votes of the participants. Results: The participants agreed that a working group should be set up for the development of structured disease- or situation-specific documentation tools (97% agreement. The final checklist included 4 recommendations concerning the setup of the working group, 12 content-related recommendations, and 3 general and technical recommendations (mean agreement [standard deviation] = 97.4% [4.0%], ranging from 84.2% to 100.0%. Discussion and Conclusion: In the future, disease- and situation-specific structured documentation tools will provide an important bridge between registries and electronic health records. Clinical documentation tools defined according to this Delphi consensus-based checklist will provide data for registries while serving as high-quality data acquisition tools in routine clinical care.

  5. The pre-licensing of a multi-purpose hybrid research reactor for high-tech applications 'MYRRHA'

    International Nuclear Information System (INIS)

    Hakimi, N.; Dams, C.; Wertelaers, A.; Nys, V.; Schrauben, M.; Dresselaers, R.

    2013-01-01

    The Belgian Nuclear Research Centre in Mol has been working for several years on the design of a multi-purpose flexible irradiation facility in order to replace the ageing BR2, a multipurpose materials testing reactor (MTR), in operation since 1962. MYRRHA, a flexible fast spectrum research reactor is conceived as an accelerator driven system (ADS), able to operate in sub-critical and critical modes. It contains a proton accelerator of 600 MeV, a spallation target and a multiplying medium with MOX fuel, cooled by liquid lead-bismuth (Pb-Bi). Since February 2011, the Belgian Nuclear Research Centre has engaged in a 'pre-licensing' process with the regulatory authority for an estimated period up to mid 2014. The paper presents on the one hand the objectives of the pre-licensing phase as well as its implementation process and on the other hand, 2 implementing instruments which have been developed by the regulatory authority providing guidance to the designer of MYRRHA in order to meet the pre-licensing phase objectives. The first instrument is a strategic note for the design and operation of MYRRHA where as the second instrument is a guidance document for the format and content of a design options and provisions file (DOPF). Both instruments have been developed taking into account that MYRRHA is an irradiation facility using a Generation IV nuclear power system's type technology (liquid metal cooled fast neutron reactor). The strategic note overview aims to cover the safety approach as well as the security requirements and safeguards obligation applicable to MYRRHA. In particular, in the strategic note, a specific attention has been paid in order to ensure that a safety, security and safeguards integrated approach will drive the development of the MYRRHA design. The safety approach focuses on the safety goals and the minimum safety objectives set by the regulatory authority for this innovative design. The DOPF overview presents its objectives and structure resuming

  6. Conceptualizing Debates in Learning and Educational Research: Toward a Complex Systems Conceptual Framework of Learning

    Science.gov (United States)

    Jacobson, Michael J.; Kapur, Manu; Reimann, Peter

    2016-01-01

    This article proposes a conceptual framework of learning based on perspectives and methodologies being employed in the study of complex physical and social systems to inform educational research. We argue that the contexts in which learning occurs are complex systems with elements or agents at different levels--including neuronal, cognitive,…

  7. Moving alcohol prevention research forward-Part I: introducing a complex systems paradigm.

    Science.gov (United States)

    Apostolopoulos, Yorghos; Lemke, Michael K; Barry, Adam E; Lich, Kristen Hassmiller

    2018-02-01

    The drinking environment is a complex system consisting of a number of heterogeneous, evolving and interacting components, which exhibit circular causality and emergent properties. These characteristics reduce the efficacy of commonly used research approaches, which typically do not account for the underlying dynamic complexity of alcohol consumption and the interdependent nature of diverse factors influencing misuse over time. We use alcohol misuse among college students in the United States as an example for framing our argument for a complex systems paradigm. A complex systems paradigm, grounded in socio-ecological and complex systems theories and computational modeling and simulation, is introduced. Theoretical, conceptual, methodological and analytical underpinnings of this paradigm are described in the context of college drinking prevention research. The proposed complex systems paradigm can transcend limitations of traditional approaches, thereby fostering new directions in alcohol prevention research. By conceptualizing student alcohol misuse as a complex adaptive system, computational modeling and simulation methodologies and analytical techniques can be used. Moreover, use of participatory model-building approaches to generate simulation models can further increase stakeholder buy-in, understanding and policymaking. A complex systems paradigm for research into alcohol misuse can provide a holistic understanding of the underlying drinking environment and its long-term trajectory, which can elucidate high-leverage preventive interventions. © 2017 Society for the Study of Addiction.

  8. 1991 Annual report on scientific programs: A broad research program on the sciences of complexity

    Energy Technology Data Exchange (ETDEWEB)

    1991-01-01

    1991 was continued rapid growth for the Santa Fe Institute (SFI) as it broadened its interdisciplinary research into the organization, evolution and operation of complex systems and sought deeply the principles underlying their dynamic behavior. Research on complex systems--the focus of work at SFI--involves an extraordinary range of topics normally studied in seemingly disparate fields. Natural systems displaying complex behavior range upwards from proteins and DNA through cells and evolutionary systems to human societies. Research models exhibiting complexity include nonlinear equations, spin glasses, cellular automata, genetic algorithms, classifier systems, and an array of other computational models. Some of the major questions facing complex systems researchers are: (1) explaining how complexity arises from the nonlinear interaction of simples components, (2) describing the mechanisms underlying high-level aggregate behavior of complex systems (such as the overt behavior of an organism, the flow of energy in an ecology, the GNP of an economy), and (3) creating a theoretical framework to enable predictions about the likely behavior of such systems in various conditions. The importance of understanding such systems in enormous: many of the most serious challenges facing humanity--e.g., environmental sustainability, economic stability, the control of disease--as well as many of the hardest scientific questions--e.g., protein folding, the distinction between self and non-self in the immune system, the nature of intelligence, the origin of life--require deep understanding of complex systems.

  9. 1991 Annual report on scientific programs: A broad research program on the sciences of complexity

    Energy Technology Data Exchange (ETDEWEB)

    1991-12-31

    1991 was continued rapid growth for the Santa Fe Institute (SFI) as it broadened its interdisciplinary research into the organization, evolution and operation of complex systems and sought deeply the principles underlying their dynamic behavior. Research on complex systems--the focus of work at SFI--involves an extraordinary range of topics normally studied in seemingly disparate fields. Natural systems displaying complex behavior range upwards from proteins and DNA through cells and evolutionary systems to human societies. Research models exhibiting complexity include nonlinear equations, spin glasses, cellular automata, genetic algorithms, classifier systems, and an array of other computational models. Some of the major questions facing complex systems researchers are: (1) explaining how complexity arises from the nonlinear interaction of simples components, (2) describing the mechanisms underlying high-level aggregate behavior of complex systems (such as the overt behavior of an organism, the flow of energy in an ecology, the GNP of an economy), and (3) creating a theoretical framework to enable predictions about the likely behavior of such systems in various conditions. The importance of understanding such systems in enormous: many of the most serious challenges facing humanity--e.g., environmental sustainability, economic stability, the control of disease--as well as many of the hardest scientific questions--e.g., protein folding, the distinction between self and non-self in the immune system, the nature of intelligence, the origin of life--require deep understanding of complex systems.

  10. Advances and Future Directions for Tuberous Sclerosis Complex Research: Recommendations From the 2015 Strategic Planning Conference.

    Science.gov (United States)

    Sahin, Mustafa; Henske, Elizabeth P; Manning, Brendan D; Ess, Kevin C; Bissler, John J; Klann, Eric; Kwiatkowski, David J; Roberds, Steven L; Silva, Alcino J; Hillaire-Clarke, Coryse St; Young, Lisa R; Zervas, Mark; Mamounas, Laura A

    2016-07-01

    On March 10 to March 12, 2015, the National Institute of Neurological Disorders and Stroke and the Tuberous Sclerosis Alliance sponsored a workshop in Bethesda, Maryland, to assess progress and new opportunities for research in tuberous sclerosis complex with the goal of updating the 2003 Research Plan for Tuberous Sclerosis (http://www.ninds.nih.gov/about_ninds/plans/tscler_research_plan.htm). In addition to the National Institute of Neurological Disorders and Stroke and Tuberous Sclerosis Alliance, participants in the strategic planning effort and workshop included representatives from six other Institutes of the National Institutes of Health, the Department of Defense Tuberous Sclerosis Complex Research Program, and a broad cross-section of basic scientists and clinicians with expertise in tuberous sclerosis complex along with representatives from the pharmaceutical industry. Here we summarize the outcomes from the extensive premeeting deliberations and final workshop recommendations, including (1) progress in the field since publication of the initial 2003 research plan for tuberous sclerosis complex, (2) the key gaps, needs, and challenges that hinder progress in tuberous sclerosis complex research, and (3) a new set of research priorities along with specific recommendations for addressing the major challenges in each priority area. The new research plan is organized around both short-term and long-term goals with the expectation that progress toward specific objectives can be achieved within a five to ten year time frame. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. Real-Time and Real-Fast Performance of General-Purpose and Real-Time Operating Systems in Multithreaded Physical Simulation of Complex Mechanical Systems

    Directory of Open Access Journals (Sweden)

    Carlos Garre

    2014-01-01

    Full Text Available Physical simulation is a valuable tool in many fields of engineering for the tasks of design, prototyping, and testing. General-purpose operating systems (GPOS are designed for real-fast tasks, such as offline simulation of complex physical models that should finish as soon as possible. Interfacing hardware at a given rate (as in a hardware-in-the-loop test requires instead maximizing time determinism, for which real-time operating systems (RTOS are designed. In this paper, real-fast and real-time performance of RTOS and GPOS are compared when simulating models of high complexity with large time steps. This type of applications is usually present in the automotive industry and requires a good trade-off between real-fast and real-time performance. The performance of an RTOS and a GPOS is compared by running a tire model scalable on the number of degrees-of-freedom and parallel threads. The benchmark shows that the GPOS present better performance in real-fast runs but worse in real-time due to nonexplicit task switches and to the latency associated with interprocess communication (IPC and task switch.

  12. Educational Research in the United States: A Survey of Pre-K-12 Teachers' Perceptions Regarding the Purpose, Conceptions, Use, Impact, and Dissemination

    Science.gov (United States)

    Mahoney, Shawn

    2013-01-01

    The purpose of this survey study was to collect data from pre-K-12 educators in the U.S. regarding their perceptions of the purpose, conceptions, use, impact, and results of educational research. The survey tool was based on existing questionnaires and case studies in the literature, as well as newly developed items. 3,908 educators in a database…

  13. Addressing the Evidence Gap in Stroke Rehabilitation for Complex Patients: A Preliminary Research Agenda.

    Science.gov (United States)

    Nelson, Michelle L; McKellar, Kaileah A; Munce, Sarah; Kelloway, Linda; Hans, Parminder Kaur; Fortin, Martin; Lyons, Renee; Bayley, Mark

    2018-06-01

    Evidence suggests that a stroke occurs in isolation (no comorbid conditions) in less than 6% of patients. Multimorbidity, compounded by psychosocial issues, makes treatment and recovery for stroke increasingly complex. Recent research and health policy documents called for a better understanding of the needs of this patient population, and for the development and testing of models of care that meet their needs. A research agenda specific to complexity is required. The primary objective of the think tank was to identify and prioritize research questions that meet the information needs of stakeholders, and to develop a research agenda specific to stroke rehabilitation and patient complexity. A modified Delphi and World Café approach underpinned the think tank meeting, approaches well recognized to foster interaction, dialogue, and collaboration between stakeholders. Forty-three researchers, clinicians, and policymakers attended a 2-day meeting. Initial question-generating activities resulted in 120 potential research questions. Sixteen high-priority research questions were identified, focusing on predetermined complexity characteristics-multimorbidity, social determinants, patient characteristics, social supports, and system factors. The final questions are presented as a prioritized research framework. An emergent result of this activity is the development of a complexity and stroke rehabilitation research network. The research agenda reflects topics of importance to stakeholders working with stroke patients with increasingly complex care needs. This robust process resulted in a preliminary research agenda that could provide policymakers with the evidence needed to make improvements toward better-organized services, better coordination between settings, improved patient outcomes, and lower system costs. Copyright © 2017 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

  14. Fostering Complexity Thinking in Action Research for Change in Social-Ecological Systems

    Directory of Open Access Journals (Sweden)

    Kevin H. Rogers

    2013-06-01

    Full Text Available Complexity thinking is increasingly being embraced by a wide range of academics and professionals as imperative for dealing with today's pressing social-ecological challenges. In this context, action researchers partner directly with stakeholders (communities, governance institutions, and work resource managers, etc. to embed a complexity frame of reference for decision making. In doing so, both researchers and stakeholders must strive to internalize not only "intellectual complexity" (knowing but also "lived complexity" (being and practicing. Four common conceptualizations of learning (explicit/tacit knowledge framework; unlearning selective exposure; conscious/competence learning matrix; and model of learning loops are integrated to provide a new framework that describes how learning takes place in complex systems. Deep reflection leading to transformational learning is required to foster the changes in mindset and behaviors needed to adopt a complexity frame of reference. We then present three broad frames of mind (openness, situational awareness, and a healthy respect for the restraint/action paradox, which each encompass a set of habits of mind, to create a useful framework that allows one to unlearn reductionist habits while adopting and embedding those more conducive to working in complex systems. Habits of mind provide useful heuristic tools to guide researchers and stakeholders through processes of participative planning and adaptive decision making in complex social-ecological systems.

  15. Interdisciplinarity, Qualitative Research, and the Complex Phenomenon: Toward an Integrative Approach to Intercultural Research

    Science.gov (United States)

    Ryan, Phillip; Kurtz, Jill Sornsen; Carter, Deanne; Pester, Danielle

    2014-01-01

    This article is a collaboration by the lead faculty member in a Masters program in Intercultural Studies and students who completed the program under his aegis. This article presents the program's approach to its research course sequence, an approach involving the integration of interdisciplinary and qualitative research. The authors first provide…

  16. Complex research of acoustic impact on gas-dust flow in vortex ...

    African Journals Online (AJOL)

    Complex research of acoustic impact on gas-dust flow in vortex-acoustic dispenser. ... PROMOTING ACCESS TO AFRICAN RESEARCH ... Introduction The processing of wastes from mining operations is usually related to the needs of related industries in raw materials. ... EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT

  17. Quantitative Research Methods in Chaos and Complexity: From Probability to Post Hoc Regression Analyses

    Science.gov (United States)

    Gilstrap, Donald L.

    2013-01-01

    In addition to qualitative methods presented in chaos and complexity theories in educational research, this article addresses quantitative methods that may show potential for future research studies. Although much in the social and behavioral sciences literature has focused on computer simulations, this article explores current chaos and…

  18. 1993 Annual report on scientific programs: A broad research program on the sciences of complexity

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1993-12-31

    This report provides a summary of many of the research projects completed by the Santa Fe Institute (SFI) during 1993. These research efforts continue to focus on two general areas: the study of, and search for, underlying scientific principles governing complex adaptive systems, and the exploration of new theories of computation that incorporate natural mechanisms of adaptation (mutation, genetics, evolution).

  19. What qualitative research can contribute to a randomized controlled trial of a complex community intervention.

    Science.gov (United States)

    Nelson, Geoffrey; Macnaughton, Eric; Goering, Paula

    2015-11-01

    Using the case of a large-scale, multi-site Canadian Housing First research demonstration project for homeless people with mental illness, At Home/Chez Soi, we illustrate the value of qualitative methods in a randomized controlled trial (RCT) of a complex community intervention. We argue that quantitative RCT research can neither capture the complexity nor tell the full story of a complex community intervention. We conceptualize complex community interventions as having multiple phases and dimensions that require both RCT and qualitative research components. Rather than assume that qualitative research and RCTs are incommensurate, a more pragmatic mixed methods approach was used, which included using both qualitative and quantitative methods to understand program implementation and outcomes. At the same time, qualitative research was used to examine aspects of the intervention that could not be understood through the RCT, such as its conception, planning, sustainability, and policy impacts. Through this example, we show how qualitative research can tell a more complete story about complex community interventions. Copyright © 2015 Elsevier Inc. All rights reserved.

  20. Using mixed methods to develop and evaluate complex interventions in palliative care research.

    Science.gov (United States)

    Farquhar, Morag C; Ewing, Gail; Booth, Sara

    2011-12-01

    there is increasing interest in combining qualitative and quantitative research methods to provide comprehensiveness and greater knowledge yield. Mixed methods are valuable in the development and evaluation of complex interventions. They are therefore particularly valuable in palliative care research where the majority of interventions are complex, and the identification of outcomes particularly challenging. this paper aims to introduce the role of mixed methods in the development and evaluation of complex interventions in palliative care, and how they may be used in palliative care research. the paper defines mixed methods and outlines why and how mixed methods are used to develop and evaluate complex interventions, with a pragmatic focus on design and data collection issues and data analysis. Useful texts are signposted and illustrative examples provided of mixed method studies in palliative care, including a detailed worked example of the development and evaluation of a complex intervention in palliative care for breathlessness. Key challenges to conducting mixed methods in palliative care research are identified in relation to data collection, data integration in analysis, costs and dissemination and how these might be addressed. the development and evaluation of complex interventions in palliative care benefit from the application of mixed methods. Mixed methods enable better understanding of whether and how an intervention works (or does not work) and inform the design of subsequent studies. However, they can be challenging: mixed method studies in palliative care will benefit from working with agreed protocols, multidisciplinary teams and engaging staff with appropriate skill sets.

  1. How to make complexity look simple? Conveying ecosystems restoration complexity for socio-economic research and public engagement

    Science.gov (United States)

    Glenk, Klaus; Byg, Anja

    2017-01-01

    Ecosystems degradation represents one of the major global challenges at the present time, threating people’s livelihoods and well-being worldwide. Ecosystem restoration therefore seems no longer an option, but an imperative. Restoration challenges are such that a dialogue has begun on the need to re-shape restoration as a science. A critical aspect of that reshaping process is the acceptance that restoration science and practice needs to be coupled with socio-economic research and public engagement. This inescapably means conveying complex ecosystem’s information in a way that is accessible to the wider public. In this paper we take up this challenge with the ultimate aim of contributing to making a step change in science’s contribution to ecosystems restoration practice. Using peatlands as a paradigmatically complex ecosystem, we put in place a transdisciplinary process to articulate a description of the processes and outcomes of restoration that can be understood widely by the public. We provide evidence of the usefulness of the process and tools in addressing four key challenges relevant to restoration of any complex ecosystem: (1) how to represent restoration outcomes; (2) how to establish a restoration reference; (3) how to cope with varying restoration time-lags and (4) how to define spatial units for restoration. This evidence includes the way the process resulted in the creation of materials that are now being used by restoration practitioners for communication with the public and in other research contexts. Our main contribution is of an epistemological nature: while ecosystem services-based approaches have enhanced the integration of academic disciplines and non-specialist knowledge, this has so far only followed one direction (from the biophysical underpinning to the description of ecosystem services and their appreciation by the public). We propose that it is the mix of approaches and epistemological directions (including from the public to the

  2. Research of the complex of functional and technological properties of animal protein

    Directory of Open Access Journals (Sweden)

    Олена Борисівна Дроменко

    2016-12-01

    Full Text Available The analysis of the results of analytical and practical research of the complex of functional and technological properties of animal protein Gelexcel A-95 as the basis for creation of complex functional additives is shown. The regularities of their changes are determined depending on technological factors. Rational parameters of animal protein rehydration, gelation conditions, emulsification for further use in the process of production of meat products are identified

  3. Tackling complexities in understanding the social determinants of health: the contribution of ethnographic research.

    Science.gov (United States)

    Bandyopadhyay, Mridula

    2011-11-25

    The complexities inherent in understanding the social determinants of health are often not well-served by quantitative approaches. My aim is to show that well-designed and well-conducted ethnographic studies have an important contribution to make in this regard. Ethnographic research designs are a difficult but rigorous approach to research questions that require us to understand the complexity of people's social and cultural lives. I draw on an ethnographic study to describe the complexities of studying maternal health in a rural area in India. I then show how the lessons learnt in that setting and context can be applied to studies done in very different settings. I show how ethnographic research depends for rigour on a theoretical framework for sample selection; why immersion in the community under study, and rapport building with research participants, is important to ensure rich and meaningful data; and how flexible approaches to data collection lead to the gradual emergence of an analysis based on intense cross-referencing with community views and thus a conclusion that explains the similarities and differences observed. When using ethnographic research design it can be difficult to specify in advance the exact details of the study design. Researchers can encounter issues in the field that require them to change what they planned on doing. In rigorous ethnographic studies, the researcher in the field is the research instrument and needs to be well trained in the method. Ethnographic research is challenging, but nevertheless provides a rewarding way of researching complex health problems that require an understanding of the social and cultural determinants of health.

  4. Agency for Healthcare Research and Quality Evidence-based Practice Center methods for systematically reviewing complex multicomponent health care interventions.

    Science.gov (United States)

    Guise, Jeanne-Marie; Chang, Christine; Viswanathan, Meera; Glick, Susan; Treadwell, Jonathan; Umscheid, Craig A; Whitlock, Evelyn; Fu, Rongwei; Berliner, Elise; Paynter, Robin; Anderson, Johanna; Motu'apuaka, Pua; Trikalinos, Tom

    2014-11-01

    The purpose of this Agency for Healthcare Research and Quality Evidence-based Practice Center methods white paper was to outline approaches to conducting systematic reviews of complex multicomponent health care interventions. We performed a literature scan and conducted semistructured interviews with international experts who conduct research or systematic reviews of complex multicomponent interventions (CMCIs) or organizational leaders who implement CMCIs in health care. Challenges identified include lack of consistent terminology for such interventions (eg, complex, multicomponent, multidimensional, multifactorial); a wide range of approaches used to frame the review, from grouping interventions by common features to using more theoretical approaches; decisions regarding whether and how to quantitatively analyze the interventions, from holistic to individual component analytic approaches; and incomplete and inconsistent reporting of elements critical to understanding the success and impact of multicomponent interventions, such as methods used for implementation the context in which interventions are implemented. We provide a framework for the spectrum of conceptual and analytic approaches to synthesizing studies of multicomponent interventions and an initial list of critical reporting elements for such studies. This information is intended to help systematic reviewers understand the options and tradeoffs available for such reviews. Copyright © 2014 Elsevier Inc. All rights reserved.

  5. Joint Research Centre Copernicus Climate Change Service (C3S) Fitness-for-Purpose (F4P) Platform

    Science.gov (United States)

    Gobron, N.; Adams, J. S.; Cappucci, F.; Lanconelli, C.; Mota, B.; Melin, F.

    2016-08-01

    This paper presents the concept and first results of the Copernicus Climate Change Service Fitness-for-Purpose (C3S F4P) project. The main goal aims at evaluating the efficiency and overall performance of the service, mainly with regard to users information needs and high level requirements. This project will also assess the fitness- for-purpose of the C3S with a specific emphasis on the needs of European Union (EU) Policies and translate these recommendations into programmatic and technical requirements. The C3S Climate Data Records (CDS) include various Essential Climate Variables (ECVs) that are derived from space sensors, including from Copernicus Sentinels sensors. One module of the F4P platform focuses on the benchmarking of data sets and algorithms, in addition to radiative transfer models used towards understanding potential discrepancies between CDS records. Methods and preliminary results of the benchmark platform are presented in this contribution.

  6. Multiple Stressors and Ecological Complexity Require A New Approach to Coral Reef Research

    Directory of Open Access Journals (Sweden)

    Linwood Hagan Pendleton

    2016-03-01

    Full Text Available Ocean acidification, climate change, and other environmental stressors threaten coral reef ecosystems and the people who depend upon them. New science reveals that these multiple stressors interact and may affect a multitude of physiological and ecological processes in complex ways. The interaction of multiple stressors and ecological complexity may mean that the negative effects on coral reef ecosystems will happen sooner and be more severe than previously thought. Yet, most research on the effects of global change on coral reefs focus on one or few stressors and pathways or outcomes (e.g. bleaching. Based on a critical review of the literature, we call for a regionally targeted strategy of mesocosm-level research that addresses this complexity and provides more realistic projections about coral reef impacts in the face of global environmental change. We believe similar approaches are needed for other ecosystems that face global environmental change.

  7. Establishment of the foundation for international collaborating research with US NASA FTCSC to develop space, military and special purpose food

    International Nuclear Information System (INIS)

    Jo, Chul Hun; Byun, Myung Woo; Lee, Ju Wun; Kim, Dong Ho; Kim, Kyung Pho; Kim, Jang Ho; Kwon, Jung Ho

    2005-08-01

    In the space era of 21st century, the advancement of aerospace field is essential for ensuring the national security and raising the national status. Internationally spacefood and space life support system is considered as an limitedly developed technology area. Establishment of the foundation for collaborating study with NASA FTCSC to develop space, military, and special food. Acquirement of the basis of the technology development for safe, long-term preservation of military and special purpose food to ensure national security as well as health and welfare

  8. Complex researches on substantiation of construction and seismic stability of large dams in seismic region

    International Nuclear Information System (INIS)

    Negmatullaev, S.Kh.; Yasunov, P.A.

    2001-01-01

    This article is devoted to complex researches on substantiation of construction and seismic stability of large dams (Nurec hydroelectric power station) in seismic region. Geological, seismological, model, and engineering investigations are discussed in this work. At construction of Nurec hydroelectric power station the rich experience is accumulated. This experience can be used in analogous seismically active regions at construction similar hydroelectric power stations.

  9. Coding for Language Complexity: The Interplay among Methodological Commitments, Tools, and Workflow in Writing Research

    Science.gov (United States)

    Geisler, Cheryl

    2018-01-01

    Coding, the analytic task of assigning codes to nonnumeric data, is foundational to writing research. A rich discussion of methodological pluralism has established the foundational importance of systematicity in the task of coding, but less attention has been paid to the equally important commitment to language complexity. Addressing the interplay…

  10. Use of Movement Imagery in Neurorehabilitation: Researching Effects of a Complex Intervention

    Science.gov (United States)

    Braun, Susy M.; Wade, Derick T.; Beurskens, Anna J. H. M.

    2011-01-01

    Since the beginning of the new millennium, the use of mental practice and movement imagery within several medical professions in rehabilitation and therapy has received an increased attention. Before this introduction in healthcare, the use of movement imagery was mainly researched in sports science. Mental practice is a complex intervention. When…

  11. A Complex Systems Framework for Research on Leadership and Organizational Dynamics in Academic Libraries

    Science.gov (United States)

    Gilstrap, Donald L.

    2009-01-01

    This article provides a historiographical analysis of major leadership and organizational development theories that have shaped our thinking about how we lead and administrate academic libraries. Drawing from behavioral, cognitive, systems, and complexity theories, this article discusses major theorists and research studies appearing over the past…

  12. Envisioning Complexity: Towards a New Conceptualization of Educational Research for Sustainability

    Science.gov (United States)

    Pipere, Anita

    2016-01-01

    This paper aims to present some conceptual insights into the research paradigm of complexity that deals with such problems like sustainability, education, and, more specifically--sustainability education. The transdisciplinary perspective and cognitive approaches of a hermeneutical cycle and semantic waves used in argumentation assist in grasping…

  13. When Complexity Theory Meets Critical Realism: A Platform for Research on Initial Teacher Education

    Science.gov (United States)

    Cochran-Smith, Marilyn; Ell, Fiona; Grudnoff, Lexie; Ludlow, Larry; Haigh, Mavis; Hill, Mary

    2014-01-01

    Many scholars have concluded that teacher education research needs to take a complex view, resist simplification, and account more fully for teacher education's contexts and processes as well as its impact on teacher candidates' and school students' learning (Cochran-Smith & Zeichner, 2005; Grossman & McDonald, 2008; Opfer & Pedder,…

  14. The center for plant and microbial complex carbohydrates at the University of Georgia Complex Carbohydrate Research Center

    Energy Technology Data Exchange (ETDEWEB)

    Albersheim, P.; Darvill, A.

    1991-08-01

    Research from the Complex Carbohydrates Research Center at the University of Georgia is presented. Topics include: Structural determination of soybean isoflavones which specifically induce Bradyrhizobium japonicum nodD1 but not the nodYABCSUIJ operon; structural analysis of the lipopolysaccharides (LPSs) from symbiotic mutants of Bradyrhizobium japonicum; structural characterization of lipooligosaccharides from Bradyrhizobium japonicum that are required for the specific nodulation of soybean; structural characterization of the LPSs from R. Leguminosarum biovar phaseoli, the symbiont of bean; characterization of bacteroid-specific LPS epitopes in R. leguminosarum biovar viciae; analysis of the surface polysaccharides of Rhizobium meliloti mutants whose lipopolysaccharides and extracellular polysaccharides can have the same function in symbiosis; characterization of a polysaccharide produced by certain Bradyrhizobium japonicum strains within soybean nodules; structural analysis of a streptococcal adhesin polysaccharide receptor; conformational studies of xyloglucan, the role of the fucosylated side chain in surface-specific cellulose-xyloglucan interactions; the structure of an acylated glucosamine oligosaccharide signal molecule (nod factor) involved in the symbiosis of Rhizobium leguminosarum biovar viciae with its host Vicia sativa; investigating membrane responses induced by oligogalacturonides in cultured cells; the polygalacturonase inhibitor protein; characterization of the self-incompatability glycoproteins from Petunia hybrida; investigation of the cell wall polysaccharide structures of Arabidopsis thaliana; and the glucan inhibition of virus infection of tabacco.

  15. Irradiation facilities for the production of radioisotopes for medical purposes and for industry at the Rossendorf Research Reactor

    International Nuclear Information System (INIS)

    Hieronymus, W.

    2007-01-01

    In 1955, the Government of the German Democratic Republic initiated radioisotope production. With that decision, the following plants received their go ahead: - Research reactor with its user facilities; - Cyclotron with its specific facilities; - Institute for radiochemistry; - Library, lecture hall, workshops and administration buildings supporting the necessary scientific and administrative environment. The Zentralinstitut fuer Kerntechnik (ZfK), also known as the Central Institute for Nuclear Technology, was founded at Rossendorf near Dresden, Germany, to house all those plants. The Rossendorf Research Reactor (RFR) was constructed in 1956-1957. That endeavour was enabled by the technological support of the former USSR under a bilateral agreement which included the delivery of a 2 MW research reactor of the WWR-S design

  16. The Text of Tile Master Agreement between the Agency and the United States of America Governing Sales of Source, By- Product and Special Nuclear Materials for research Purposes

    International Nuclear Information System (INIS)

    1974-01-01

    The text of the Master Agreement Governing Sales of Source, Bye Product and Special Nuclear Materials for Research Purposes, which has been concluded between the Agency and the Government of the United States of America, is reproduced herein for the information of all Members,

  17. General-purpose heat source: Research and development program, radioisotope thermoelectric generator/thin fragment impact test

    International Nuclear Information System (INIS)

    Reimus, M.A.H.; Hinckley, J.E.

    1996-11-01

    The general-purpose heat source provides power for space missions by transmitting the heat of 238 Pu decay to an array of thermoelectric elements in a radioisotope thermoelectric generator (RTG). Because the potential for a launch abort or return from orbit exists for any space mission, the heat source response to credible accident scenarios is being evaluated. This test was designed to provide information on the response of a loaded RTG to impact by a fragment similar to the type of fragment produced by breakup of the spacecraft propulsion module system. The results of this test indicated that impact by a thin aluminum fragment traveling at 306 m/s may result in significant damage to the converter housing, failure of one fueled clad, and release of a small quantity of fuel

  18. A qualitative inquiry into the challenges and complexities of research supervision: viewpoints of postgraduate students and faculty members.

    Science.gov (United States)

    Yousefi, Alireza; Bazrafkan, Leila; Yamani, Nikoo

    2015-07-01

    The supervision of academic theses at the Universities of Medical Sciences is one of the most important issues with several challenges. The aim of the present study is to discover the nature of problems and challenges of thesis supervision in Iranian universities of medical sciences. The study was conducted with a qualitative method using conventional content analysis approach. Nineteen faculty members, using purposive sampling, and 11 postgraduate medical sciences students (Ph.D students and residents) were selected on the basis of theoretical sampling. The data were gathered through semi-structured interviews and field observations in Shiraz and Isfahan universities of medical sciences from September 2012 to December 2014. The qualitative content analysis was used with a conventional approach to analyze the data. While experiencing the nature of research supervision process, faculties and the students faced some complexities and challenges in the research supervision process. The obtained codes were categorized under 4 themes Based on the characteristics; included "contextual problem", "role ambiguity in thesis supervision", "poor reflection in supervision" and "ethical problems". The result of this study revealed that there is a need for more attention to planning and defining the supervisory, and research supervision. Also, improvement of the quality of supervisor and students relationship must be considered behind the research context improvement in research supervisory area.

  19. NATO Advanced Research Workshop on Recent advances in Nonlinear Dynamics and Complex System Physics

    CERN Document Server

    Casati, Giulio; Complex Phenomena in Nanoscale Systems

    2009-01-01

    Nanoscale physics has become one of the rapidly developing areas of contemporary physics because of its direct relevance to newly emerging area, nanotechnologies. Nanoscale devices and quantum functional materials are usually constructed based on the results of fundamental studies on nanoscale physics. Therefore studying physical phenomena in nanosized systems is of importance for progressive development of nanotechnologies. In this context study of complex phenomena in such systems and using them for controlling purposes is of great practical importance. Namely, such studies are brought together in this book, which contains 27 papers on various aspects of nanoscale physics and nonlinear dynamics.

  20. System of complex neurorehabilitation of newborns with cerebral pathology// Saratov Journal of Medical Scientific Research

    Directory of Open Access Journals (Sweden)

    Panina O.S.

    2011-06-01

    Full Text Available Perinatal CNS damage is one of most actual problem of neonatology and its rate in structure of children invalidity is 60%. The purpose was to learn clinical efficiency of a course transcranial magnet therapy in complex with preparation Pantogam in rehabilitation of children with perinatal CNS damage. Materials. Clinical and neurophysiological studies were performed in 60 newborn children from 10 to 28 day of life. Results. The study showed that results of combined treatment (traveling impulse magnet field + Pantogam was significantly (1,5 times higher that efficacy of routine treatment only

  1. Being scientifical: Popularity, purpose and promotion of amateur research and investigation groups in the U.S

    Science.gov (United States)

    Hill, Sharon A.

    21st century television and the Internet are awash in content regarding amateur paranormal investigators and research groups. These groups proliferated after reality investigation programs appeared on television. Exactly how many groups are active in the U.S. at any time is not known. The Internet provides an ideal means for people with niche interests to find each other and organize activities. This study collected information from 1000 websites of amateur research and investigation groups (ARIGs) to determine their location, area of inquiry, methodology and, particularly, to determine if they state that they use science as part of their mission, methods or goals. 57.3% of the ARIGs examined specifically noted or suggested use of science as part of the groups' approach to investigation and research. Even when not explicit, ARIGs often used science-like language, symbols and methods to describe their groups' views or activities. Yet, non-scientific and subjective methods were described as employed in conjunction with objective methods. Furthermore, what were considered scientific processes by ARIGs did not match with established methods and the ethos of the scientific research community or scientific processes of investigation. ARIGs failed to display fundamental understanding regarding objectivity, methodological naturalism, peer review, critical thought and theoretical plausibility. The processes of science appear to be mimicked to present a serious and credible reputation to the non-scientific public. These processes are also actively promoted in the media and directly to the local public as "scientific". These results highlight the gap between the scientific community and the lay public regarding the understanding of what it means to do science and what criteria are necessary to establish reliable knowledge about the world.

  2. A complex, nonlinear dynamic systems perspective on Ayurveda and Ayurvedic research.

    Science.gov (United States)

    Rioux, Jennifer

    2012-07-01

    The fields of complexity theory and nonlinear dynamic systems (NDS) are relevant for analyzing the theory and practice of Ayurvedic medicine from a Western scientific perspective. Ayurvedic definitions of health map clearly onto the tenets of both systems and complexity theory and focus primarily on the preservation of organismic equanimity. Health care research informed by NDS and complexity theory would prioritize (1) ascertaining patterns reflected in whole systems as opposed to isolating components; (2) relationships and dynamic interaction rather than static end-points; (3) transitions, change and cumulative effects, consistent with delivery of therapeutic packages in the reality of the clinical setting; and (4) simultaneously exploring both local and global levels of healing phenomena. NDS and complexity theory are useful in examining nonlinear transitions between states of health and illness; the qualitative nature of shifts in health status; and looking at emergent properties and behaviors stemming from interactions between organismic and environmental systems. Complexity and NDS theory also demonstrate promise for enhancing the suitability of research strategies applied to Ayurvedic medicine through utilizing core concepts such as initial conditions, emergent properties, fractal patterns, and critical fluctuations. In the Ayurvedic paradigm, multiple scales and their interactions are addressed simultaneously, necessitating data collection on change patterns that occur on continuums of both time and space, and are viewed as complementary rather than isolated and discrete. Serious consideration of Ayurvedic clinical understandings will necessitate new measurement options that can account for the relevance of both context and environmental factors, in terms of local biology and the processual features of the clinical encounter. Relevant research design issues will need to address clinical tailoring strategies and provide mechanisms for mapping patterns of

  3. Developing a framework for qualitative engineering: Research in design and analysis of complex structural systems

    Science.gov (United States)

    Franck, Bruno M.

    1990-01-01

    The research is focused on automating the evaluation of complex structural systems, whether for the design of a new system or the analysis of an existing one, by developing new structural analysis techniques based on qualitative reasoning. The problem is to identify and better understand: (1) the requirements for the automation of design, and (2) the qualitative reasoning associated with the conceptual development of a complex system. The long-term objective is to develop an integrated design-risk assessment environment for the evaluation of complex structural systems. The scope of this short presentation is to describe the design and cognition components of the research. Design has received special attention in cognitive science because it is now identified as a problem solving activity that is different from other information processing tasks (1). Before an attempt can be made to automate design, a thorough understanding of the underlying design theory and methodology is needed, since the design process is, in many cases, multi-disciplinary, complex in size and motivation, and uses various reasoning processes involving different kinds of knowledge in ways which vary from one context to another. The objective is to unify all the various types of knowledge under one framework of cognition. This presentation focuses on the cognitive science framework that we are using to represent the knowledge aspects associated with the human mind's abstraction abilities and how we apply it to the engineering knowledge and engineering reasoning in design.

  4. Joint purpose?

    DEFF Research Database (Denmark)

    Pristed Nielsen, Helene

    2013-01-01

    Starting from Crenshaw´s point that antiracism often fails to interrogate patriarchy and that feminism often reproduces racist practices (1991: 1252), this paper asks: What are the theoretical reasons for believing that feminism and anti-racism can be regarded as fighting for the joint purpose...

  5. Research Area 3: Mathematics (3.1 Modeling of Complex Systems)

    Science.gov (United States)

    2017-10-31

    Title: RESEARCH AREA 3: MATHEMATICS (3.1 Modeling of Complex Systems). Proposal should be directed to Dr. John Lavery Report Term: 0-Other Email ...Paolo Rosso Email : prosso@dsic.upv.es values of the profile characteristics taken by the users), intersection (they represent the relationship between...accuracy, especially when adding fully connected layers at the end of the network. This work has resulted in the writing of a manuscript for the Journal

  6. Using video-based observation research methods in primary care health encounters to evaluate complex interactions.

    Science.gov (United States)

    Asan, Onur; Montague, Enid

    2014-01-01

    The purpose of this paper is to describe the use of video-based observation research methods in primary care environment and highlight important methodological considerations and provide practical guidance for primary care and human factors researchers conducting video studies to understand patient-clinician interaction in primary care settings. We reviewed studies in the literature which used video methods in health care research, and we also used our own experience based on the video studies we conducted in primary care settings. This paper highlighted the benefits of using video techniques, such as multi-channel recording and video coding, and compared "unmanned" video recording with the traditional observation method in primary care research. We proposed a list that can be followed step by step to conduct an effective video study in a primary care setting for a given problem. This paper also described obstacles, researchers should anticipate when using video recording methods in future studies. With the new technological improvements, video-based observation research is becoming a promising method in primary care and HFE research. Video recording has been under-utilised as a data collection tool because of confidentiality and privacy issues. However, it has many benefits as opposed to traditional observations, and recent studies using video recording methods have introduced new research areas and approaches.

  7. [Application of hair analysis of selected psychoactive substances for medico-legal purposes. Part II. Cases of complex fatal poisonings: interactions of heroine - cocaine - amphetamines].

    Science.gov (United States)

    Rojek, Sebastian; Kłys, Małgorzata; Rzepecka-Woźniak, Ewa; Konopka, Tomasz

    2010-01-01

    The study represents an attempt at employing segmental hair analysis in complex poisonings with xenobiotic mixtures of heroine - cocaine - amphetamines in the context of the cause of death as a consequence of complex interaction mechanisms which occurred prior to death. Two cases of complex poisonings: heroine - cocaine and heroine - cocaine - amphetamines were analyzed and documented with macro- and microscopic examinations and complex toxicological examinations, including the analysis of classic biological material, i.e. samples of selective blood, and alternative material, i.e. hair samples. Determinations of opioids, cocaine and its metabolite and amphetamines in the hair biological matrix were performed using high performance liquid chromatography--atmospheric pressure chemical ionization--tandem mass spectrometry (HPLC-APCI-MS-MS). Segmental hair analysis of the investigated cases indicated a prolonged intake of similar psychoactive substances and a developed adaptation of the addicted to interaction mechanisms, which, however, led gradually to multiorgan anatomopathological changes, and in consequence to death.

  8. [Collections of human biological resources for research purposes: from regulations to the need of a guide of good collection practices].

    Science.gov (United States)

    Le Roux, N; de Montgolfier, S; di Donato, J-H; Boccon-Gibod, L; Teillac, P; Hervé, C; Berthon, P

    2003-12-01

    In France, collections of human biological resources are regulated by the "Bioethics Law", currently in revision. Hence, we analyse the regulatory and ethical issues of these practices in the context of scientific research. The ultimate aim of such collections is to improve biological and medical knowledge. We think that the French regulatory system is quite complicated and non-explicit for "collection holders". The multiplicity of legal texts concerning this activity has made their application difficult, especially in the absence of application decrees. The project amending the actual law has clarified the legal status of collections but it did not shed light on the status of human body detached parts. Furthermore, the text is still very far from the international bioethical recommendations, and does not reflect the actual collection's implementation. The establishment of a guideline of Good Collection Practices, based on clear principles, should help to simplify the situation, especially when it is imbedded in the regulation and linked to control procedures. It would allow a balance between collective interests and the protection of individuals, taking into account of the international highly competitive scientific and economical constraints. The major issue is to preserve and to perpetuate the existing and future collections because of their precious value as an important tool for biomedical knowledge. The efficiency of a regulation depends on its legibility and accessibility, two requirements that seem to determine the acceptance of the regulatory tool and its application allowing subsequently to reach fairness in proceedings.

  9. Final report: A Broad Research Project in the Sciences of Complexity; FINAL

    International Nuclear Information System (INIS)

    None

    2000-01-01

    Previous DOE support for ''A Broad Research Program in the Sciences of Complexity'' permitted the Santa Fe Institute to initiate new collaborative research within its Integrative Core activities as well as to host visitors to participate in research on specific topics that serve as motivation and testing-ground for the study of general principles of complex systems. The critical aspect of this support is its effectiveness in seeding new areas of research. Indeed, this Integrative Core has been the birthplace of dozens of projects that later became more specifically focused and then won direct grant support independent of the core grants. But at early stages most of this multidisciplinary research was unable to win grant support as individual projects-both because it did not match well with existing grant program guidelines, and because the amount of handing needed was often too modest to justify a formal proposal to an agency. In fact, one of the attributes of core support has been that it permitted SFI to encourage high-risk activities because the cost was quite low. What is significant is how many of those initial efforts have been productive in the SFI environment. Many of SFI'S current research foci began with a short visit from a researcher new to the SFI community, or as small working groups that brought together carefully selected experts from a variety of fields. As mentioned above, many of the ensuing research projects are now being supported by other funding agencies or private foundations. Some of these successes are described

  10. Final report: A Broad Research Project in the Sciences of Complexity

    Energy Technology Data Exchange (ETDEWEB)

    None

    2000-02-01

    Previous DOE support for ''A Broad Research Program in the Sciences of Complexity'' permitted the Santa Fe Institute to initiate new collaborative research within its Integrative Core activities as well as to host visitors to participate in research on specific topics that serve as motivation and testing-ground for the study of general principles of complex systems. The critical aspect of this support is its effectiveness in seeding new areas of research. Indeed, this Integrative Core has been the birthplace of dozens of projects that later became more specifically focused and then won direct grant support independent of the core grants. But at early stages most of this multidisciplinary research was unable to win grant support as individual projects--both because it did not match well with existing grant program guidelines, and because the amount of handing needed was often too modest to justify a formal proposal to an agency. In fact, one of the attributes of core support has been that it permitted SFI to encourage high-risk activities because the cost was quite low. What is significant is how many of those initial efforts have been productive in the SFI environment. Many of SFI'S current research foci began with a short visit from a researcher new to the SFI community, or as small working groups that brought together carefully selected experts from a variety of fields. As mentioned above, many of the ensuing research projects are now being supported by other funding agencies or private foundations. Some of these successes are described.

  11. The photographic knee pain map: locating knee pain with an instrument developed for diagnostic, communication and research purposes.

    Science.gov (United States)

    Elson, D W; Jones, S; Caplan, N; Stewart, S; St Clair Gibson, A; Kader, D F

    2011-12-01

    Pain maps are used to determine the location of pain. Knee pain maps have previously been described, but only one study has reported on reliability and none report validity. The present study describes the generation of a photographic knee pain map (PKPM) together with its validity and reliability. A photographic representation of a pair of knees was chosen by 26 patients, (66.7%) from a group of 39. The selected photograph was modified and a template of anatomical zones was generated. The opinions of 25 independent subject matter experts were canvassed and validity ratios calculated for these zones, ranged from 0.28 to 0.84. Hypothetical comparisons were made between the PKPM and an alternative knee pain map, in a cross-sectional group of 26 patients (35 knees). Convergent patterns of validity were found where hypothesised. Reliability was determined using a different cohort of 44 patients (58 knees) who completed the PKPM before and after a sampling delay. Four of these patients were excluded with a short sampling delay. Calculated agreement of test-retest reproducibility was fair to good. All of the completed PKPM (151 knees) were then subject to further analysis where inter-rater reproducibility was good to very good and intra-rater reproducibility was very good. The PKPM is readily accessible to patients with low completion burden. It is both valid and reliable and we suggest it can be used in both clinical and research settings. Further studies are planned to explore its predictive ability as a diagnostic tool. The PKPM can be found at www.photographickneepainmap.com. Copyright © 2010 Elsevier B.V. All rights reserved.

  12. Diverse Complexities, Complex Diversities: Resisting "Normal Science" in Pedagogical and Research Methodologies. A Perspective from Aotearoa (New Zealand)

    Science.gov (United States)

    Ritchie, Jenny

    2016-01-01

    This paper offers an overview of complexities of the contexts for education in Aotearoa, which include the need to recognise and include Maori (Indigenous) perspectives, but also to extend this inclusion to the context of increasing ethnic diversity. These complexities include the situation of worsening disparities between rich and poor which…

  13. Organizational Influences on Interdisciplinary Interactions during Research and Design of Large-Scale Complex Engineered Systems

    Science.gov (United States)

    McGowan, Anna-Maria R.; Seifert, Colleen M.; Papalambros, Panos Y.

    2012-01-01

    The design of large-scale complex engineered systems (LaCES) such as an aircraft is inherently interdisciplinary. Multiple engineering disciplines, drawing from a team of hundreds to thousands of engineers and scientists, are woven together throughout the research, development, and systems engineering processes to realize one system. Though research and development (R&D) is typically focused in single disciplines, the interdependencies involved in LaCES require interdisciplinary R&D efforts. This study investigates the interdisciplinary interactions that take place during the R&D and early conceptual design phases in the design of LaCES. Our theoretical framework is informed by both engineering practices and social science research on complex organizations. This paper provides preliminary perspective on some of the organizational influences on interdisciplinary interactions based on organization theory (specifically sensemaking), data from a survey of LaCES experts, and the authors experience in the research and design. The analysis reveals couplings between the engineered system and the organization that creates it. Survey respondents noted the importance of interdisciplinary interactions and their significant benefit to the engineered system, such as innovation and problem mitigation. Substantial obstacles to interdisciplinarity are uncovered beyond engineering that include communication and organizational challenges. Addressing these challenges may ultimately foster greater efficiencies in the design and development of LaCES and improved system performance by assisting with the collective integration of interdependent knowledge bases early in the R&D effort. This research suggests that organizational and human dynamics heavily influence and even constrain the engineering effort for large-scale complex systems.

  14. Capturing complexity in work disability research: application of system dynamics modeling methodology.

    Science.gov (United States)

    Jetha, Arif; Pransky, Glenn; Hettinger, Lawrence J

    2016-01-01

    Work disability (WD) is characterized by variable and occasionally undesirable outcomes. The underlying determinants of WD outcomes include patterns of dynamic relationships among health, personal, organizational and regulatory factors that have been challenging to characterize, and inadequately represented by contemporary WD models. System dynamics modeling (SDM) methodology applies a sociotechnical systems thinking lens to view WD systems as comprising a range of influential factors linked by feedback relationships. SDM can potentially overcome limitations in contemporary WD models by uncovering causal feedback relationships, and conceptualizing dynamic system behaviors. It employs a collaborative and stakeholder-based model building methodology to create a visual depiction of the system as a whole. SDM can also enable researchers to run dynamic simulations to provide evidence of anticipated or unanticipated outcomes that could result from policy and programmatic intervention. SDM may advance rehabilitation research by providing greater insights into the structure and dynamics of WD systems while helping to understand inherent complexity. Challenges related to data availability, determining validity, and the extensive time and technical skill requirements for model building may limit SDM's use in the field and should be considered. Contemporary work disability (WD) models provide limited insight into complexity associated with WD processes. System dynamics modeling (SDM) has the potential to capture complexity through a stakeholder-based approach that generates a simulation model consisting of multiple feedback loops. SDM may enable WD researchers and practitioners to understand the structure and behavior of the WD system as a whole, and inform development of improved strategies to manage straightforward and complex WD cases.

  15. Using a Design Science Perspective to Understand a Complex Design-Based Research Process

    DEFF Research Database (Denmark)

    Bækgaard, Lars

    2012-01-01

    The purpose of the paper is to demonstrate how a design science perspective can be used to describe and understand a set of related design-based research processes. We describe and analyze a case study in a manner that is inspired by design science. The case study involves the design of modeling......-based research processes. And we argue that a design science perspective may be useful for both researchers and practitioners....... tools and the redesign of an information service in a library. We use a set of guidelines from a design science perspective to organize the description and analysis of the case study. By doing this we demonstrate the usefulness of design science as an analytical tool for understanding related design...

  16. Final Report: A Broad Research Project on the Sciences of Complexity, September 15, 1994 - November 15, 1999

    Energy Technology Data Exchange (ETDEWEB)

    None

    2000-02-01

    DOE support for a broad research program in the sciences of complexity permitted the Santa Fe Institute to initiate new collaborative research within its integrative core activities as well as to host visitors to participate in research on specific topics that serve as motivation and testing ground for the study of the general principles of complex systems. Results are presented on computational biology, biodiversity and ecosystem research, and advanced computing and simulation.

  17. Research on Extraction of Ship Target in Complex Sea-sky Background

    International Nuclear Information System (INIS)

    Kang, W J; Ding, X M; Cui, J W; Ao, L

    2006-01-01

    Research on the extraction of ship target in complex sea-sky background has important value to improve the capability of imaging-typed sea navigation and nautical traffic control systems. According to the imaging property of complex sea-sky background, a reliable ship target extraction method is proposed in this paper. The general guide line is that getting the sea-sky division line as a priori knowledge and then the target potential area is determined through discontinuous region of the sea-sky division line. Firstly, a local selective window filter is adopted to filter the image; secondly, eight directions Sobel operator edge detection method and gradient Hough transform are combined to extract sea-sky division line in the image; then a multi-histogram matching technique is adopted to remove the sea and sky background and thus ship target is extracted from complex background. The experiments show that our method has the merits of robustness to noise, small computational complexity and stability

  18. Complex Intelligent Systems: Juxtaposition of Foundational Notions and a Research Agenda

    Directory of Open Access Journals (Sweden)

    Petros A.M. Gelepithis

    2001-12-01

    Full Text Available Abstract: The cardinality of the class, C , of complex intelligent systems, i.e., systems of intelligent systems and their resources, is steadily increasing. Such an increase, whether designed, sometimes changes significantly and fundamentally, the structure of C . Recently,the study of members of C and its structure comes under a variety of multidisciplinary headings the most prominent of which include General Systems Theory, Complexity Science, Artificial Life, and Cybernetics. Their common characteristic is the quest for a unified theory of a certain class of systems like a living system or an organisation. So far, the only candidate for a general theory of intelligent systems is Newell's Soar. To my knowledge there is presently no candidate theory of C except Newell's claimed extensibility of Soar. This paper juxtaposes the elements of Newell's conceptual basis with those of an alternative conceptual framework based on the thesis that communication and understanding are the primary processes shaping the structure of C and its members. It is patently obvious that a research agenda for the study of C can be extremely varied and long. The third section of this paper presents a highly selective research agenda that aims to provoke discussion among complexity theory scientists.

  19. Theory and research in audiology education: understanding and representing complexity through informed methodological decisions.

    Science.gov (United States)

    Ng, Stella L

    2013-05-01

    The discipline of audiology has the opportunity to embark on research in education from an informed perspective, learning from professions that began this journey decades ago. The goal of this article is to position our discipline as a new member in the academic field of health professional education (HPE), with much to learn and contribute. In this article, I discuss the need for theory in informing HPE research. I also stress the importance of balancing our research goals by selecting appropriate methodologies for relevant research questions, to ensure that we respect the complexity of social processes inherent in HPE. Examples of relevant research questions are used to illustrate the need to consider alternative methodologies and to rethink the traditional hierarchy of evidence. I also provide an example of the thought processes and decisions that informed the design of an educational research study using a constructivist grounded theory methodology. As audiology enters the scholarly field of HPE, we need to arm ourselves with some of the knowledge and perspective that informs the field. Thus, we need to broaden our conceptions of what we consider to be appropriate styles of academic writing, relevant research questions, and valid evidence. Also, if we are to embark on qualitative inquiry into audiology education (or other audiology topics), we need to ensure that we conduct this research with an adequate understanding of the theories and methodologies informing such approaches. We must strive to conduct high quality, rigorous qualitative research more often than uninformed, generic qualitative research. These goals are imperative to the advancement of the theoretical landscape of audiology education and evolving the place of audiology in the field of HPE. American Academy of Audiology.

  20. Embracing Complexity of Crop Phytobiomes with a Multidisciplinary Roadmap for Phytobiomes Research and an Industry-Academic Research Alliance

    Science.gov (United States)

    Eversole, K.

    2016-12-01

    To meet the demands of a global human population expected to exceed 9.6 billion by 2055, crop productivity in sustainable agricultural systems must improve considerably in the face of a steadily changing climate and increased biotic and abiotic stressors. Traditional agricultural sciences have relied mostly on research within individual disciplines and linear, reductionist approaches for crop improvement. While significant advancements have been made in developing and characterizing genetic and genomic resources for crops, we still have a very limited understanding of genotype by environment x management (GxExM) interactions that determine productivity, sustainability, quality, and the ability to withstand biotic and abiotic stressors. Embracing complexity and the non-linear organization and regulation of biological systems would enable a paradigm shift in breeding and crop production by allowing us to move towards a holistic, systems level approach that integrates a wide range of disciplines (e.g., geophysics, biology, agronomy, physiology, genomics, genetics, breeding, physics, pattern recognition, feedback loops, modeling, and engineering) and knowledge about crop phytobiomes (i.e., plants, their associated macro- and micro-organisms, and the geophysical environment of distinct geographical sites). By focusing on the phytobiome, we will be able to elucidate, quantify, model, predict, act, manipulate, and prevent and ultimately prescribe the cropping systems, methods, and management practices most suited for a particular farm, grassland, or forest. The recently released, multidisciplinary roadmap entitled Phytobiomes: A Roadmap for Research and Translation and the new International Alliance for Phytobiomes Research, an industry-academic consortium, will be presented.

  1. Research on Characteristics, Antioxidant and Antitumor Activities of Dihydroquercetin and Its Complexes

    Directory of Open Access Journals (Sweden)

    Yan Zhang

    2017-12-01

    Full Text Available Dihydroquercetin is a kind of dihydroflavonol compounds with antioxidant, antitumor, antivirus and radioresistance activities. This study attempted to produce the dihydroquercetin complexes with lecithin and β-cyclodextrin, and research their characteristics and bioactivities via ultraviolet spectrum (UV, infrared spectroscopy (IR, scanning electron microscope (SEM, differential scanning calorimetry (DSC, X-ray diffraction spectrum (XRD, and MTT assay. Results showed that the complexes with lecithin and β-cyclodextrin could improve the solubility and dissolution rate, and remove the characteristic endothermic peak of dihydroquercetin. IR spectra proved their interaction, and results of SEM and XRD showed the amorphous characteristics of the dihydroquercetin compounds. These results indicated that dihydroquercetin was combined by lecithin or β-cyclodextrin with better physical and chemical properties, which would effectively improve the application value in the food and drug industries.

  2. NATO Advanced Research Workshop on Dynamics of Polyatomic Van der Waals Complexes

    CERN Document Server

    Janda, Kenneth

    1991-01-01

    This publication is the Proceedings of the NATO Advanced Research Workshop (ARW) on the Dynamics of Polyatomic Van der Waals Molecules held at the Chateau de Bonas, Castera-Verduzan, France, from August 21 through August 26, 1989. Van der Waals complexes provide important model problems for understanding energy transfer and dissipation. These processes can be described in great detail for Van der Waals complexes, and the insight gained from such studies can be applied to more complicated chemical problems that are not amenable to detailed study. The workshop concentrated on the current questions and future prospects for extend­ ing our highly detailed knowledge of triatomic Van der Waals molecule dynamics to polyatomic molecules and clusters (one molecule surrounded by several, or up to sev­ eral tens of, atoms). Both experimental and theoretical studies were discussed, with particular emphasis on the dynamical behavior of dissociation as observed in the dis­ tributions of quantum states of the dissociatio...

  3. Public responses to the sharing and linkage of health data for research purposes: a systematic review and thematic synthesis of qualitative studies.

    Science.gov (United States)

    Aitken, Mhairi; de St Jorre, Jenna; Pagliari, Claudia; Jepson, Ruth; Cunningham-Burley, Sarah

    2016-11-10

    The past 10 years have witnessed a significant growth in sharing of health data for secondary uses. Alongside this there has been growing interest in the public acceptability of data sharing and data linkage practices. Public acceptance is recognised as crucial for ensuring the legitimacy of current practices and systems of governance. Given the growing international interest in this area this systematic review and thematic synthesis represents a timely review of current evidence. It highlights the key factors influencing public responses as well as important areas for further research. This paper reports a systematic review and thematic synthesis of qualitative studies examining public attitudes towards the sharing or linkage of health data for research purposes. Twenty-five studies were included in the review. The included studies were conducted primarily in the UK and North America, with one study set in Japan, another in Sweden and one in multiple countries. The included studies were conducted between 1999 and 2013 (eight studies selected for inclusion did not report data collection dates). The qualitative methods represented in the studies included focus groups, interviews, deliberative events, dialogue workshops and asynchronous online interviews. Key themes identified across the corpus of studies related to the conditions necessary for public support/acceptability, areas of public concern and implications for future research. The results identify a growing body of evidence pointing towards widespread general-though conditional-support for data linkage and data sharing for research purposes. Whilst a variety of concerns were raised (e.g. relating to confidentiality, individuals' control over their data, uses and abuses of data and potential harms arising) in cases where participants perceived there to be actual or potential public benefits from research and had trust in the individuals or organisations conducting and/or overseeing data linkage/sharing, they

  4. A world class nuclear research reactor complex for South Africa's nuclear future

    International Nuclear Information System (INIS)

    Keshaw, Jeetesh

    2008-01-01

    South Africa recently made public its rather ambitious goals pertaining to nuclear energy developments in a Draft Policy and Strategy issued for public comment. Not much attention was given to an important tool for nuclear energy research and development, namely a well equipped and maintained research reactor, which on its own does not do justice to its potential, unless it is fitted with all the ancillaries and human resources as most first world countries have. In South Africa's case it is suggested to establish at least one Nuclear Energy Research and Development Centre at such a research reactor, where almost all nuclear energy related research can be carried out on par with some of the best in the world. The purpose of this work is to propose how this could be done, and motivate why it is important that it be done with great urgency, and with full involvement of young professionals, if South Africa wishes to face up to the challenges mentioned in the Draft Strategy and Policy. (authors)

  5. A world class nuclear research reactor complex for South Africa's nuclear future

    Energy Technology Data Exchange (ETDEWEB)

    Keshaw, Jeetesh [South African Young Nuclear Professional Society, PO Box 9396, Centurion, 0157 (South Africa)

    2008-07-01

    South Africa recently made public its rather ambitious goals pertaining to nuclear energy developments in a Draft Policy and Strategy issued for public comment. Not much attention was given to an important tool for nuclear energy research and development, namely a well equipped and maintained research reactor, which on its own does not do justice to its potential, unless it is fitted with all the ancillaries and human resources as most first world countries have. In South Africa's case it is suggested to establish at least one Nuclear Energy Research and Development Centre at such a research reactor, where almost all nuclear energy related research can be carried out on par with some of the best in the world. The purpose of this work is to propose how this could be done, and motivate why it is important that it be done with great urgency, and with full involvement of young professionals, if South Africa wishes to face up to the challenges mentioned in the Draft Strategy and Policy. (authors)

  6. Use of computerized tomography in the Multibrauch Research and Technology Complex ''Eye microsurgery''

    International Nuclear Information System (INIS)

    Fedorov, S.N.; Ivashina, A.I.; Anisimov, S.I.; Prokopenko, L.N.; Moskvichev, A.L.

    1989-01-01

    The paper is devoted to analysis of the results of computerized tomography (CT) in 1000 patients examined in te Multibranch Research and Technology Complex ''Eye Microsurgery''. The specific feature of CT in this institution is that 52% of all investigations of ophthalmological patients fall to the share of eyeball abnormality and 40% - to a study of the other parts of the organ of vision. CT indications are extended for low tension glaucoma, complicated high myopia, and for monitoring the position of microsurgical implants. The use of CT is such a highly specialized medical institution as the MRTC ''Eye Microsurgery'' is considered indispensable

  7. Shielding considerations for an electron linear accelerator complex for high energy physics and photonics research

    International Nuclear Information System (INIS)

    Holmes, J.A.; Huntzinger, C.J.

    1987-01-01

    Radiation shielding considerations for a major high-energy physics and photonics research complex which comprise a 50 MeV electron linear accelerator injector, a 1.0 GeV electron linear accelerator and a 1.3 GeV storage ring are discussed. The facilities will be unique because of the close proximity of personnel to the accelerator beam lines, the need to adapt existing facilities and shielding materials and the application of strict ALARA dose guidelines while providing maximum access and flexibility during a phased construction program

  8. The Y-12 National Security Complex Foreign Research Reactor Uranium Supply Production

    Energy Technology Data Exchange (ETDEWEB)

    Nelson, T. [Nuclear Technology and Nonproliferation Programs, B and W Y-12, L.L.C., Y-12 National Security Complex, Oak Ridge, Tennessee (United States); Keller, A.P. [Disposition and Supply Programs, B and W Y-12, L.L.C., Y-12 National Security Complex, Oak Ridge, Tennessee (United States)

    2011-07-01

    The Foreign Research Reactor (FRR) Uranium Supply Program at the Y-12 National Security Complex supports the nonproliferation objectives of the National Nuclear Security Administration (NNSA) HEU Disposition, the Reduced Enrichment Research and Test Reactors (RERTR), and the United States (U.S.) FRR Spent Nuclear Fuel (SNF) Acceptance Programs. The FRR Supply Program supports the important U.S. government nuclear nonproliferation commitment to serve as a reliable and cost-effective uranium supplier for those foreign research reactors that are converting or have converted to Low-Enriched Uranium (LEU) fuel under the RERTR Program. The NNSA Y-12 Site Office maintains the prime contracts with foreign government agencies for the supply of LEU for their research reactors. The LEU is produced by down blending Highly Enriched Uranium (HEU) that has been declared surplus to the U.S. national defense needs. The down blending and sale of the LEU supports the Surplus HEU Disposition Program Record of Decision to make the HEU non-weapons usable and to recover the economic value of the uranium to the extent feasible. In addition to uranium metal feedstock for fuel fabrication, Y-12 can produce LEU in different forms to support new fuel development or target fabrication for medical isotope production. With production improvements and efficient delivery preparations, Y-12 continues to successfully support the global research reactor community. (author)

  9. Performance of the Research Animal Holding Facility (RAHF) and General Purpose Work Station (GPWS) and other hardware in the microgravity environment

    Science.gov (United States)

    Hogan, Robert P.; Dalton, Bonnie P.

    1991-01-01

    This paper discusses the performance of the Research Animal Holding Facility (RAHF) and General Purpose Work Station (GPWS) plus other associated hardware during the recent flight of Spacelab Life Sciences 1 (SLS-1). The RAHF was developed to provide proper housing (food, water, temperature control, lighting and waste management) for up to 24 rodents during flights on the Spacelab. The GPWS was designed to contain particulates and toxic chemicals generated during plant and animal handling and dissection/fixation activities during space flights. A history of the hardware development involves as well as the redesign activities prior to the actual flight are discussed.

  10. The Einstein Observatory: A New Public/Private Observatory Complex for Community Education and Scientific Research

    Science.gov (United States)

    Sowell, J.

    1999-12-01

    The Development Authority of Cherokee County (Georgia) is leading a public/private partnership of business/industry professionals, educators, and university scientists that seeks to develop a national prototype educational and scientific research facility for grades K-12, as well as college-level research, that will inspire our youth to become literate in science and technology. In particular, the goal is to make this complex a science, math, and engineering magnet learning facility and to raise the average SAT scores of local area students by 100 points. A dark-site mountain, nestled on the foothills of the Blue Ridge Mountains at the northern-most edge of Atlanta, will become the home for the "Einstein" Observatory. The complex will have four telescopes: one 50-inch, one 24-inch, and two 16-inch telescopes. Each telescope will have digital cameras and an optic-fiber feed to a single, medium-resolution spectroscope. All four telescopes will be electronically accessible from local schools. Professional astronomers will establish suitable observational research projects and will lead K-12 and college students in the acquisition and analysis of data. Astronomers will also assist the local area schoolteachers in methods for nurturing children's scientific inquiry. The observatory mountain will have 100 platform locations for individual viewing by visiting families, school groups, and amateur astronomers. The Atlanta Astronomer Club will provide numerous evening programs and viewing opportunities for the general public. An accompanying Planetarium & Science Center will be located on the nearby campus of Reinhardt College. The Planetarium & Science Center will be integrated with Reinhardt College's theme of learning focused upon studying the past and present as a basis for projecting the future.

  11. Foreign research reactor uranium supply program: The Y-12 national security complex process

    International Nuclear Information System (INIS)

    Nelson, T.; Eddy, B.G.

    2010-01-01

    The Foreign Research Reactor (FRR) Uranium Supply Program at the Y-12 National Security Complex supports the nonproliferation objectives of the HEU Disposition Program, the Reduced Enrichment Research and Test Reactors (RERTR) Program, and the United States FRR Spent Nuclear Fuel (SNF) Acceptance Program. The Y-12 National Nuclear Security Administration (NNSA) Y-12 Site Office maintains the prime contracts with foreign governments for the supply of Low-Enriched Uranium (LEU) for their research reactors. The LEU is produced by down blending Highly Enriched Uranium (HEU) that has been declared surplus to the U.S. national defense needs. The down blending and sale of the LEU supports the Surplus HEU Disposition Program Record of Decision to make the HEU non-weapons usable and to recover the economic value of the uranium to the extent feasible. This program supports the important U.S. government and nuclear nonproliferation commitment to serve as a reliable and cost-effective uranium supplier for those foreign research reactors that are converting or have converted to LEU fuel under the guidance of the NNSA RERTR Program. In conjunction with the FRR SNF Acceptance Program which supports the global nonproliferation efforts to disposition U.S.-origin HEU, the Y-12 FRR Uranium Supply Program can provide the LEU for the replacement fuel fabrication. In addition to feedstock for fuel fabrication, Y-12 supplies LEU for target fabrication for medical isotope production. The Y-12 process uses supply forecasting tools, production improvements and efficient delivery preparations to successfully support the global research reactor community

  12. Complexities and Controversies in Himalayan Research: A Call for Collaboration and Rigor for Better Data

    Directory of Open Access Journals (Sweden)

    Surendra P. Singh

    2015-11-01

    Full Text Available The Himalaya range encompasses enormous variation in elevation, precipitation, biodiversity, and patterns of human livelihoods. These mountains modify the regional climate in complex ways; the ecosystem services they provide influence the lives of almost 1 billion people in 8 countries. However, our understanding of these ecosystems remains rudimentary. The 2007 Intergovernmental Panel on Climate Change report that erroneously predicted a date for widespread glacier loss exposed how little was known of Himalayan glaciers. Recent research shows how variably glaciers respond to climate change in different Himalayan regions. Alarmist theories are not new. In the 1980s, the Theory of Himalayan Degradation warned of complete forest loss and devastation of downstream areas, an eventuality that never occurred. More recently, the debate on hydroelectric construction appears driven by passions rather than science. Poor data, hasty conclusions, and bad science plague Himalayan research. Rigorous sampling, involvement of civil society in data collection, and long-term collaborative research involving institutions from across the Himalaya are essential to improve knowledge of this region.

  13. Enriching gender in physics education research: A binary past and a complex future

    Science.gov (United States)

    Traxler, Adrienne

    2017-01-01

    This talk draws on research in physics, science education, and women's studies to propose a more nuanced treatment of gender in physics education research (PER). A growing body of PER has examined gender differences in students' participation, performance, and attitudes toward physics. Though valuable, this body of work often follows a ``binary deficit'' model of gender, where the achievements of men are implicitly taken as the most appropriate standard and where individual experiences and student identities are undervalued. I will discuss more up-to-date viewpoints on gender from other fields, as well as work on the intersection of identities [e.g., gender with race and ethnicity, or with lesbian, gay, bisexual, and transgender (LGBT) status]. A few PER studies examine the intersection of gender and race, and identify the lack of a unitary identity as a key challenge of ``belonging'' in physics. Acknowledging this complexity of identity allows further critique of the binary deficit model, which casts gender as a fixed binary trait and frames research questions around investigating deficiencies in women rather than issues of systemic bias. More nuanced models of gender allow a greater range and fluidity of gender identities, and highlight deficiencies in data that exclude women's experiences. I will conclude by suggesting new investigations that might build on an expanded gender framework in PER.

  14. Complexity, rhizome and magma, three key elements in pattern building in environmental research

    International Nuclear Information System (INIS)

    Noguera de Echeverri, Ana Patricia

    2002-01-01

    The following reading synthesizes the rur-urban-agrary environmental research pattern that appear from the research Caldas Agrary Environmental Profile (IDEA, National University, Manizales - Colciencias, 1998 - 2000). This pattern is constructed from three ideas of the contemporary philosophy: complexity, rhizome and magma that comes from another disciplines: the mathematics, botanic, and geology. The genetics-historical method that follows this article, starts with a critical analysis to the relation forms between society and nature that belongs to the modernity, to do then, a presentation of the influence of the ecology in the construction of new relations between society and nature, culture and nature, and the influence of the theory of systems in a systemic view of society, culture, and nature. Finish with a presentation of the pattern ecosystem-culture made for Augusto Angel Maya and the critical-development that becomes form this pattern, that we had named rur-urban-agrary rhizoma. For example we show how this research pattern let us to amplify the methodology of river basins that we use inside the Agrary Environmental Profile

  15. The Use of Complex Adaptive Systems as a Generative Metaphor in an Action Research Study of an Organisation

    Science.gov (United States)

    Brown, Callum

    2008-01-01

    Understanding the dynamic behaviour of organisations is challenging and this study uses a model of complex adaptive systems as a generative metaphor to address this challenge. The research question addressed is: How might a conceptual model of complex adaptive systems be used to assist in understanding the dynamic nature of organisations? Using an…

  16. Diverse complexities, complex diversities: Resisting ‘normal science’ in pedagogical and research methodologies. A perspective from Aotearoa (New Zealand

    Directory of Open Access Journals (Sweden)

    Ritchie Jenny

    2016-06-01

    Full Text Available This paper offers an overview of complexities of the contexts for education in Aotearoa, which include the need to recognise and include Māori (Indigenous perspectives, but also to extend this inclusion to the context of increasing ethnic diversity. These complexities include the situation of worsening disparities between rich and poor which disproportionately position Māori and those from Pacific Island backgrounds in situations of poverty. It then offers a brief critique of government policies before providing some examples of models that resist ‘normal science’ categorisations. These include: the Māori values underpinning the effective teachers’ profile of the Kotahitanga project and of the Māori assessment model for early childhood education; the dispositions identified in a Samoan model for assessing young children’s learning; and the approach developed for assessing Māori children’s literacy and numeracy within schools where Māori language is the medium of instruction. These models all position learning within culturally relevant frames that are grounded in non-Western onto-epistemologies which include spiritual, cultural, and collective aspirations.

  17. Systems Engineering Design Via Experimental Operation Research: Complex Organizational Metric for Programmatic Risk Environments (COMPRE)

    Science.gov (United States)

    Mog, Robert A.

    1999-01-01

    Unique and innovative graph theory, neural network, organizational modeling, and genetic algorithms are applied to the design and evolution of programmatic and organizational architectures. Graph theory representations of programs and organizations increase modeling capabilities and flexibility, while illuminating preferable programmatic/organizational design features. Treating programs and organizations as neural networks results in better system synthesis, and more robust data modeling. Organizational modeling using covariance structures enhances the determination of organizational risk factors. Genetic algorithms improve programmatic evolution characteristics, while shedding light on rulebase requirements for achieving specified technological readiness levels, given budget and schedule resources. This program of research improves the robustness and verifiability of systems synthesis tools, including the Complex Organizational Metric for Programmatic Risk Environments (COMPRE).

  18. Complexity explained

    CERN Document Server

    Erdi, Peter

    2008-01-01

    This book explains why complex systems research is important in understanding the structure, function and dynamics of complex natural and social phenomena. Readers will learn the basic concepts and methods of complex system research.

  19. Research on the Purpose and Strategies of Advertising Translation%广告翻译的目的及其策略的应用研究

    Institute of Scientific and Technical Information of China (English)

    苏伟钧

    2013-01-01

      An advertisement should be placed when a commodity or service is to be introduced into international markets. Inevita⁃bly it involves advertising translation for its cross-cultural advertisement in different regions of the world. The thesis, according to the purpose of advertising translation, is to explore some common translation strategies through researching on the headlines and slogans of advertisements.%  一种商品或服务要进入国际市场,无可避免地需要广告。这种跨地域、跨文化的宣传,必然涉及到广告翻译。该文结合广告翻译的目的,通过研究广告标题或口号,探索常用的广告翻译策略。

  20. Conceptual analyses of neutronic and equilibrium refueling parameters to develop a cost-effective multi-purpose pool-type research reactor using WIMSD and CITVAP codes

    Energy Technology Data Exchange (ETDEWEB)

    Hedayat, Afshin, E-mail: ahedayat@aeoi.org.ir

    2016-12-01

    Highlights: • Introducing a high-beneficent and low-cost multipurpose research reactor. • High technical documents and standard safety issues are introduced coherently. • High effective conceptual neutronic analyses and fuel management strategy. • Gaining high score design criteria and safety margins via 3-D core modeling. • Capacity and capability to produce all medical and industrial radioisotopes. - Abstract: In this paper, neutronic and equilibrium refueling parameters of a multi-purpose cost-effective research reactor have been studied and analyzed. It has been tried to provide periodic and long-term requirements of the irradiating applications coherently. The WIMSD5B and CITVAP codes are used to calculate neutronic parameters and simulate fuel management strategy. The used nuclear data, codes, and calculating methods have been severally benchmarked and verified, successfully. Fundamental concepts, design criteria, and safety issues are introduced and discussed, coherently. Design criteria are selected to gain the most economic benefits per capital costs via minimum required reactor power. Accurate, fast and simplified models have been tried for an integrated decision making and analyses using deterministic codes. Core management, power effects, fuel consumption and burn up effects, and also a complete simulation of the fuel management strategy are presented and analyzed. Results show that the supposed reactor core design can be promisingly suitable in accordance with the commercial multi-purpose irradiating applications. It also retains Operating Limits and Conditions (OLCs) due to standard safety issues, conservatively where safety parameters are calculated using best estimate tools. Such reactor core configuration and integrated refueling task can effectively enhance the Quality Assurance (QA) of the general irradiating applications of the current MTR within their power limits and corresponding OLCs.

  1. On analyzing the results of empirical research into the life-purpose orientations of adults of various ethnic identities and religious affiliati.

    Directory of Open Access Journals (Sweden)

    Abakumova I. V.

    2016-05-01

    Full Text Available The research in question investigates life-purpose orientations and values of various groups of a population living in a multicultural area with a variety of ethnic and religious communities. Members may have different attitudes to one and the same set of values due to their specific cultural traditions and religious guidelines. A common set of life-purpose orientations and values as well as distinctly different ones were identified in the research. It employed an ethno-psychological questionnaire designed specifically to that end and psychometric instruments aimed at identifying the values of the adults of various ethnic identities and religious affiliations. Residents of a multi-cultural area in the south of Russia who belong to different denominations were surveyed. It is stated that there is a substantial difference between the sets of values held by Baptists and Buddhists and representatives of other ethnic and religious groups (Muslims and Christians participating in this investigation. The survey found that all of the Baptist and Buddhist respondents were described by a high-to-medium level of civil identity. Indifference to ethnic standards and a failure to accept the culture of their own people were found among all of the respondents; it was displayed by a small proportion of Orthodox Christians, whereas all of the Buddhists under investigation had a positive ethnic identity, and a certain proportion of Muslims and Catholics as well as a tiny proportion of Orthodox believers reported that they placed a priority for ethnic rights over human rights. Among all of the denominations surveyed, the majority of respondents surveyed have a positive attitude towards both their own nation and other nations.

  2. Applications of systems thinking and soft operations research in managing complexity from problem framing to problem solving

    CERN Document Server

    2016-01-01

    This book captures current trends and developments in the field of systems thinking and soft operations research which can be applied to solve today's problems of dynamic complexity and interdependency. Such ‘wicked problems’ and messes are seemingly intractable problems characterized as value-laden, ambiguous, and unstable, that resist being tamed by classical problem solving. Actions and interventions associated with this complex problem space can have highly unpredictable and unintended consequences. Examples of such complex problems include health care reform, global climate change, transnational serious and organized crime, terrorism, homeland security, human security, disaster management, and humanitarian aid. Moving towards the development of solutions to these complex problem spaces depends on the lens we use to examine them and how we frame the problem. It will be shown that systems thinking and soft operations research has had great success in contributing to the management of complexity. .

  3. Rapid qualitative research methods during complex health emergencies: A systematic review of the literature.

    Science.gov (United States)

    Johnson, Ginger A; Vindrola-Padros, Cecilia

    2017-09-01

    The 2013-2016 Ebola outbreak in West Africa highlighted both the successes and limitations of social science contributions to emergency response operations. An important limitation was the rapid and effective communication of study findings. A systematic review was carried out to explore how rapid qualitative methods have been used during global heath emergencies to understand which methods are commonly used, how they are applied, and the difficulties faced by social science researchers in the field. We also asses their value and benefit for health emergencies. The review findings are used to propose recommendations for qualitative research in this context. Peer-reviewed articles and grey literature were identified through six online databases. An initial search was carried out in July 2016 and updated in February 2017. The PRISMA checklist was used to guide the reporting of methods and findings. The articles were assessed for quality using the MMAT and AACODS checklist. From an initial search yielding 1444 articles, 22 articles met the criteria for inclusion. Thirteen of the articles were qualitative studies and nine used a mixed-methods design. The purpose of the rapid studies included: the identification of causes of the outbreak, and assessment of infrastructure, control strategies, health needs and health facility use. The studies varied in duration (from 4 days to 1 month). The main limitations identified by the authors were: the low quality of the collected data, small sample sizes, and little time for cross-checking facts with other data sources to reduce bias. Rapid qualitative methods were seen as beneficial in highlighting context-specific issues that need to be addressed locally, population-level behaviors influencing health service use, and organizational challenges in response planning and implementation. Recommendations for carrying out rapid qualitative research in this context included the early designation of community leaders as a point of

  4. Design and Developmental Research on the VV&A of Complex Simulation System

    Directory of Open Access Journals (Sweden)

    Liu Li

    2016-01-01

    Full Text Available The Verification, Validation and Accreditation (VV&A of a complex simulation system is a complex systems engineering. Based on the brief introduction to the concept of VV&A, this paper puts forward its design principles, approaches and basic contents, expounds the typical developing process and predicts its up-to-date technology developing trend of complex simulation system.

  5. HPLC studies of aquatic humic compounds and complexes from the Drigg Research Site, Cumbria

    International Nuclear Information System (INIS)

    Smith, B.

    1991-01-01

    This report describes an investigation into the applicability of high performance liquid chromatographic techniques for the separation of the complex mixtures of organic acids commonly found in groundwaters. This work has shown that reverse phase ion-pair chromatography using a large pore stationary phase can be successfully applied to humic material in both natural and concentrated groundwater from the Drigg Research Site. The methodology separates the organic species into a number of well resolved components the majority of which have a molecular weight of greater than 500 Dalton. Separations obtained have been qualitatively and quantitatively analysed using a Diode array spectrophotometer. The components in excess of 500 Dalton show UV absorption spectra similar to humic and fulvic acids where as the component with a molecular weight of less than 500 Dalton shows a sharp UV absorption cutoff at 230 nm. It was noted that this component was not removed by passage through DEAEA cellulose. Reverse phase HPLC was also investigated, and results were found to be consistent with a separation based on an ion-repulsion/size exclusion mechanism. It was concluded that any separation based on this mechanism is likely to suffer from poor inter run reproducibility and must therefore be discounted as a suitable method. Similarly, ion-suppression reverse phase was shown to be equally impracticable, requiring a mobile phase pH of less than 2 to obtain separation (this low pH renders a silica based stationary phase unstable). (author)

  6. The Results of Complex Research of GSS "SBIRS-Geo 2" Behavior in the Orbit

    Science.gov (United States)

    Sukhov, P. P.; Epishev, V. P.; Sukhov, K. P.; Karpenko, G. F.; Motrunich, I. I.

    2017-04-01

    The new generation of geosynchronous satellites SBIRS of US Air Force early warning system series (Satellite Early Warning System) replaced the previous DSP-satellite series (Defense Support Program). Currently from the territory of Ukraine, several GSS of DSP series and one "SBIRS-Geo 2" are available to observation. During two years of observations, we have received and analyzed for two satellites more than 30 light curves in B, V, R photometric system. As a result of complex research, we propose a model of "SBIRS-Geo" 2 orbital behavior compared with the same one of the DSP-satellite. To control the entire surface of the Earth with 15-16 sec interval, including the polar regions, 4 SBIRS satellites located every 90 deg. along the equator are enough in GEO orbit. Since DSP-satellites provide the coverage of the Earth's surface to 83 deg. latitudes with a period of 50 sec, DSP-satellites should be 8. All the conclusions were made based on an analysis of photometric and coordinate observations using the simulation of the dynamics of their orbital behavior.

  7. A Pragmatic Approach to Guide Implementation Evaluation Research: Strategy Mapping for Complex Interventions

    Directory of Open Access Journals (Sweden)

    Alexis K. Huynh

    2018-05-01

    for producing valid and reliable process evaluation data, mapping implementation strategies has informed development of a pragmatic blueprint for implementation and longitudinal analyses and evaluation activities.DiscussionWe update recent recommendations on specification of implementation strategies by considering the implications for multi-strategy frameworks and propose an approach for mapping the use of implementation strategies within complex, multi-level interventions, in support of rigorous evaluation. Developing pragmatic tools to aid in operationalizing the conduct of implementation and evaluation activities is essential to enacting sound implementation research.

  8. Research on application of complex-genetic algorithm in nuclear component optimal design

    International Nuclear Information System (INIS)

    He Shijing; Yan Changqi; Wang Jianjun; Wang Meng

    2010-01-01

    Complex algorithm is one of the most commonly used methods in the mechanical design optimization, such as the optimization of nuclear component. An improved method,complex-genetic algorithm(CGA), is developed based on traditional complex algorithm(TCA), in which the disadvantages of TCA have been overcome. An optimal calculation,which represents the pressurizer, is carried out in order to analyze the optimization capability of CGA. The results show that CGA has better optimizing performance than TCA. (authors)

  9. Enriching gender in physics education research: A binary past and a complex future

    Directory of Open Access Journals (Sweden)

    Adrienne L. Traxler

    2016-08-01

    Full Text Available [This paper is part of the Focused Collection on Gender in Physics.] In this article, we draw on previous reports from physics, science education, and women’s studies to propose a more nuanced treatment of gender in physics education research (PER. A growing body of PER examines gender differences in participation, performance, and attitudes toward physics. We have three critiques of this work: (i it does not question whether the achievements of men are the most appropriate standard, (ii individual experiences and student identities are undervalued, and (iii the binary model of gender is not questioned. Driven by these critiques, we propose a conception of gender that is more up to date with other fields and discuss gender as performance as an extended example. We also discuss work on the intersection of identities [e.g., gender with race and ethnicity, socioeconomic status, lesbian, gay, bisexual, and transgender (LGBT status], much of which has been conducted outside of physics. Within PER, some studies examine the intersection of gender and race, and identify the lack of a single identity as a key challenge of “belonging” in physics. Acknowledging this complexity enables us to further critique what we term a binary gender deficit model. This framework, which is implicit in much of the gender-based PER, casts gender as a fixed binary trait and suggests that women are deficient in characteristics necessary to succeed. Alternative models of gender allow a greater range and fluidity of gender identities, and highlight deficiencies in data that exclude women’s experiences. We suggest new investigations that diverge from this expanded gender framework in PER.

  10. How the Center for Public Partnerships and Research Navigates Complex Social Problems to Make a Collective Difference.

    Science.gov (United States)

    Counts, Jacqueline; Gillam, Rebecca; Garstka, Teri A; Urbach, Ember

    2018-01-01

    The challenge of maximizing the well-being of children, youth, and families is recognizing that change occurs within complex social systems. Organizations dedicated to improving practice, advancing knowledge, and informing policy for the betterment of all must have the right approach, structure, and personnel to work in these complex systems. The University of Kansas Center for Public Partnerships and Research cultivates a portfolio of innovation, research, and data science approaches positioned to help move social service fields locally, regionally, and nationally. Mission, leadership, and smart growth guide our work and drive our will to affect positive change in the world.

  11. Using Multiple Sources of Information in Establishing Text Complexity. Reading Research Report. #11.03

    Science.gov (United States)

    Hiebert, Elfrieda H.

    2011-01-01

    A focus of the Common Core State Standards/English Language Arts (CCSS/ELA) is that students become increasingly more capable with complex text over their school careers. This focus has redirected attention to the measurement of text complexity. Although CCSS/ELA suggests multiple criteria for this task, the standards offer a single measure of…

  12. Theoretical research on effects of substituents and the solvent on quadruple hydrogen bonded complexes

    Directory of Open Access Journals (Sweden)

    Lingjia Xu

    2007-04-01

    Full Text Available Semiempirical AM1 and INDO/CIS methods were used to study the structures and spectroscopy of hydrogen bonded complexes formed by the oligophenyleneethynylene (monomer A with isophthalic acid (monomer B. The binding energies of the complexes are lowered by increasing electron-donating abilities of the substituents near the hydrogen bonds on monomer A. The first absorptions in the electronic spectra and the vibration frequencies of the N-H bonds in the IR spectra for the complexes are both red-shifted compared with those of the monomers. The presence of dimethylsulfoxide (DMSO can reduce the binding energy of the complex through hydrogen bonding. This results in a blue-shift for the first absorption in the electronic spectrum and red-shift for the vibration frequencies of the N-H bonds in the IR spectrum of the complex.

  13. The contribution of qualitative research in designing a complex intervention for secondary prevention of coronary heart disease in two different healthcare systems.

    LENUS (Irish Health Repository)

    Corrrigan, Mairead

    2006-01-01

    BACKGROUND: Developing complex interventions for testing in randomised controlled trials is of increasing importance in healthcare planning. There is a need for careful design of interventions for secondary prevention of coronary heart disease (CHD). It has been suggested that integrating qualitative research in the development of a complex intervention may contribute to optimising its design but there is limited evidence of this in practice. This study aims to examine the contribution of qualitative research in developing a complex intervention to improve the provision and uptake of secondary prevention of CHD within primary care in two different healthcare systems. METHODS: In four general practices, one rural and one urban, in Northern Ireland and the Republic of Ireland, patients with CHD were purposively selected. Four focus groups with patients (N = 23) and four with staff (N = 29) informed the development of the intervention by exploring how it could be tailored and integrated with current secondary prevention activities for CHD in the two healthcare settings. Following an exploratory trial the acceptability and feasibility of the intervention were discussed in four focus groups (17 patients) and 10 interviews (staff). The data were analysed using thematic analysis. RESULTS: Integrating qualitative research into the development of the intervention provided depth of information about the varying impact, between the two healthcare systems, of different funding and administrative arrangements, on their provision of secondary prevention and identified similar barriers of time constraints, training needs and poor patient motivation. The findings also highlighted the importance to patients of stress management, the need for which had been underestimated by the researchers. The qualitative evaluation provided depth of detail not found in evaluation questionnaires. It highlighted how the intervention needed to be more practical by minimising administration

  14. The contribution of qualitative research in designing a complex intervention for secondary prevention of coronary heart disease in two different healthcare systems

    Directory of Open Access Journals (Sweden)

    Leathem Claire S

    2006-07-01

    Full Text Available Abstract Background Developing complex interventions for testing in randomised controlled trials is of increasing importance in healthcare planning. There is a need for careful design of interventions for secondary prevention of coronary heart disease (CHD. It has been suggested that integrating qualitative research in the development of a complex intervention may contribute to optimising its design but there is limited evidence of this in practice. This study aims to examine the contribution of qualitative research in developing a complex intervention to improve the provision and uptake of secondary prevention of CHD within primary care in two different healthcare systems. Methods In four general practices, one rural and one urban, in Northern Ireland and the Republic of Ireland, patients with CHD were purposively selected. Four focus groups with patients (N = 23 and four with staff (N = 29 informed the development of the intervention by exploring how it could be tailored and integrated with current secondary prevention activities for CHD in the two healthcare settings. Following an exploratory trial the acceptability and feasibility of the intervention were discussed in four focus groups (17 patients and 10 interviews (staff. The data were analysed using thematic analysis. Results Integrating qualitative research into the development of the intervention provided depth of information about the varying impact, between the two healthcare systems, of different funding and administrative arrangements, on their provision of secondary prevention and identified similar barriers of time constraints, training needs and poor patient motivation. The findings also highlighted the importance to patients of stress management, the need for which had been underestimated by the researchers. The qualitative evaluation provided depth of detail not found in evaluation questionnaires. It highlighted how the intervention needed to be more practical by minimising

  15. The contribution of qualitative research in designing a complex intervention for secondary prevention of coronary heart disease in two different healthcare systems.

    Science.gov (United States)

    Corrrigan, Mairead; Cupples, Margaret E; Smith, Susan M; Byrne, Molly; Leathem, Claire S; Clerkin, Pauline; Murphy, Andrew W

    2006-07-18

    Developing complex interventions for testing in randomised controlled trials is of increasing importance in healthcare planning. There is a need for careful design of interventions for secondary prevention of coronary heart disease (CHD). It has been suggested that integrating qualitative research in the development of a complex intervention may contribute to optimising its design but there is limited evidence of this in practice. This study aims to examine the contribution of qualitative research in developing a complex intervention to improve the provision and uptake of secondary prevention of CHD within primary care in two different healthcare systems. In four general practices, one rural and one urban, in Northern Ireland and the Republic of Ireland, patients with CHD were purposively selected. Four focus groups with patients (N = 23) and four with staff (N = 29) informed the development of the intervention by exploring how it could be tailored and integrated with current secondary prevention activities for CHD in the two healthcare settings. Following an exploratory trial the acceptability and feasibility of the intervention were discussed in four focus groups (17 patients) and 10 interviews (staff). The data were analysed using thematic analysis. Integrating qualitative research into the development of the intervention provided depth of information about the varying impact, between the two healthcare systems, of different funding and administrative arrangements, on their provision of secondary prevention and identified similar barriers of time constraints, training needs and poor patient motivation. The findings also highlighted the importance to patients of stress management, the need for which had been underestimated by the researchers. The qualitative evaluation provided depth of detail not found in evaluation questionnaires. It highlighted how the intervention needed to be more practical by minimising administration, integrating role plays into behaviour

  16. A model for integrating clinical care and basic science research, and pitfalls of performing complex research projects for addressing a clinical challenge.

    Science.gov (United States)

    Steck, R; Epari, D R; Schuetz, M A

    2010-07-01

    The collaboration of clinicians with basic science researchers is crucial for addressing clinically relevant research questions. In order to initiate such mutually beneficial relationships, we propose a model where early career clinicians spend a designated time embedded in established basic science research groups, in order to pursue a postgraduate qualification. During this time, clinicians become integral members of the research team, fostering long term relationships and opening up opportunities for continuing collaboration. However, for these collaborations to be successful there are pitfalls to be avoided. Limited time and funding can lead to attempts to answer clinical challenges with highly complex research projects characterised by a large number of "clinical" factors being introduced in the hope that the research outcomes will be more clinically relevant. As a result, the complexity of such studies and variability of its outcomes may lead to difficulties in drawing scientifically justified and clinically useful conclusions. Consequently, we stress that it is the basic science researcher and the clinician's obligation to be mindful of the limitations and challenges of such multi-factorial research projects. A systematic step-by-step approach to address clinical research questions with limited, but highly targeted and well defined research projects provides the solid foundation which may lead to the development of a longer term research program for addressing more challenging clinical problems. Ultimately, we believe that it is such models, encouraging the vital collaboration between clinicians and researchers for the work on targeted, well defined research projects, which will result in answers to the important clinical challenges of today. Copyright (c) 2010 Elsevier Ltd. All rights reserved.

  17. STRING 2008 hold at CERN -- the largest and most important conference on String Theory with the mostly active researchers in the field. The main purpose of the conference is to review the latest developments for experts.

    CERN Multimedia

    Maximilien Brice

    2008-01-01

    STRING 2008 hold at CERN -- the largest and most important conference on String Theory with the mostly active researchers in the field. The main purpose of the conference is to review the latest developments for experts.

  18. Modeling, Simulation and Analysis of Complex Networked Systems: A Program Plan for DOE Office of Advanced Scientific Computing Research

    Energy Technology Data Exchange (ETDEWEB)

    Brown, D L

    2009-05-01

    Many complex systems of importance to the U.S. Department of Energy consist of networks of discrete components. Examples are cyber networks, such as the internet and local area networks over which nearly all DOE scientific, technical and administrative data must travel, the electric power grid, social networks whose behavior can drive energy demand, and biological networks such as genetic regulatory networks and metabolic networks. In spite of the importance of these complex networked systems to all aspects of DOE's operations, the scientific basis for understanding these systems lags seriously behind the strong foundations that exist for the 'physically-based' systems usually associated with DOE research programs that focus on such areas as climate modeling, fusion energy, high-energy and nuclear physics, nano-science, combustion, and astrophysics. DOE has a clear opportunity to develop a similarly strong scientific basis for understanding the structure and dynamics of networked systems by supporting a strong basic research program in this area. Such knowledge will provide a broad basis for, e.g., understanding and quantifying the efficacy of new security approaches for computer networks, improving the design of computer or communication networks to be more robust against failures or attacks, detecting potential catastrophic failure on the power grid and preventing or mitigating its effects, understanding how populations will respond to the availability of new energy sources or changes in energy policy, and detecting subtle vulnerabilities in large software systems to intentional attack. This white paper outlines plans for an aggressive new research program designed to accelerate the advancement of the scientific basis for complex networked systems of importance to the DOE. It will focus principally on four research areas: (1) understanding network structure, (2) understanding network dynamics, (3) predictive modeling and simulation for complex

  19. Modeling, Simulation and Analysis of Complex Networked Systems: A Program Plan for DOE Office of Advanced Scientific Computing Research

    International Nuclear Information System (INIS)

    Brown, D.L.

    2009-01-01

    Many complex systems of importance to the U.S. Department of Energy consist of networks of discrete components. Examples are cyber networks, such as the internet and local area networks over which nearly all DOE scientific, technical and administrative data must travel, the electric power grid, social networks whose behavior can drive energy demand, and biological networks such as genetic regulatory networks and metabolic networks. In spite of the importance of these complex networked systems to all aspects of DOE's operations, the scientific basis for understanding these systems lags seriously behind the strong foundations that exist for the 'physically-based' systems usually associated with DOE research programs that focus on such areas as climate modeling, fusion energy, high-energy and nuclear physics, nano-science, combustion, and astrophysics. DOE has a clear opportunity to develop a similarly strong scientific basis for understanding the structure and dynamics of networked systems by supporting a strong basic research program in this area. Such knowledge will provide a broad basis for, e.g., understanding and quantifying the efficacy of new security approaches for computer networks, improving the design of computer or communication networks to be more robust against failures or attacks, detecting potential catastrophic failure on the power grid and preventing or mitigating its effects, understanding how populations will respond to the availability of new energy sources or changes in energy policy, and detecting subtle vulnerabilities in large software systems to intentional attack. This white paper outlines plans for an aggressive new research program designed to accelerate the advancement of the scientific basis for complex networked systems of importance to the DOE. It will focus principally on four research areas: (1) understanding network structure, (2) understanding network dynamics, (3) predictive modeling and simulation for complex networked systems

  20. Research of experience of leading foreign countries in the management by a build complex

    OpenAIRE

    Borovik, Yu

    2010-01-01

    In the article the experience of leading foreign countries is explored in the management by build industry and possibilities of his application in the management by the transport build complex of Ukraine.

  1. Cynefin as Reference Framework to Facilitate Insight and Decision-Making in Complex Contexts of Biomedical Research

    Directory of Open Access Journals (Sweden)

    Gerd Kempermann

    2017-11-01

    Full Text Available The Cynefin scheme is a concept of knowledge management, originally devised to support decision making in management, but more generally applicable to situations, in which complexity challenges the quality of insight, prediction, and decision. Despite the fact that life itself, and especially the brain and its diseases, are complex to the extent that complexity could be considered their cardinal feature, complex problems in biomedicine are often treated as if they were actually not more than the complicated sum of solvable sub-problems. Because of the emergent properties of complex contexts this is not correct. With a set of clear criteria Cynefin helps to set apart complex problems from “simple/obvious,” “complicated,” “chaotic,” and “disordered” contexts in order to avoid misinterpreting the relevant causality structures. The distinction comes with the insight, which specific kind of knowledge is possible in each of these categories and what are the consequences for resulting decisions and actions. From student's theses over the publication and grant writing process to research politics, misinterpretation of complexity can have problematic or even dangerous consequences, especially in clinical contexts. Conceptualization of problems within a straightforward reference language like Cynefin improves clarity and stringency within projects and facilitates communication and decision-making about them.

  2. The complex nature of mixed farming systems requires multidimensional actions supported by integrative research and development efforts

    DEFF Research Database (Denmark)

    González-García, E; Gourdine, J L; Alexandre, G

    2012-01-01

    the requirement for a change in research strategies and initiatives through the development of a complex but necessary multi-/inter-/trans-disciplinary teamwork spirit. We stress as essential the collaboration and active participation of local and regional actors, stakeholders and end-users in the identification...

  3. 42 CFR 68a.1 - What is the scope and purpose of the NIH Clinical Research Loan Repayment Program for Individuals...

    Science.gov (United States)

    2010-10-01

    ..., INTERNSHIPS, TRAINING NATIONAL INSTITUTES OF HEALTH (NIH) CLINICAL RESEARCH LOAN REPAYMENT PROGRAM FOR... to the award of educational loan payments under the NIH Clinical Research Loan Repayment Program for... relative to income, to conduct clinical research as NIH employees. ...

  4. Theory of Change: a theory-driven approach to enhance the Medical Research Council's framework for complex interventions.

    Science.gov (United States)

    De Silva, Mary J; Breuer, Erica; Lee, Lucy; Asher, Laura; Chowdhary, Neerja; Lund, Crick; Patel, Vikram

    2014-07-05

    The Medical Research Councils' framework for complex interventions has been criticized for not including theory-driven approaches to evaluation. Although the framework does include broad guidance on the use of theory, it contains little practical guidance for implementers and there have been calls to develop a more comprehensive approach. A prospective, theory-driven process of intervention design and evaluation is required to develop complex healthcare interventions which are more likely to be effective, sustainable and scalable. We propose a theory-driven approach to the design and evaluation of complex interventions by adapting and integrating a programmatic design and evaluation tool, Theory of Change (ToC), into the MRC framework for complex interventions. We provide a guide to what ToC is, how to construct one, and how to integrate its use into research projects seeking to design, implement and evaluate complex interventions using the MRC framework. We test this approach by using ToC within two randomized controlled trials and one non-randomized evaluation of complex interventions. Our application of ToC in three research projects has shown that ToC can strengthen key stages of the MRC framework. It can aid the development of interventions by providing a framework for enhanced stakeholder engagement and by explicitly designing an intervention that is embedded in the local context. For the feasibility and piloting stage, ToC enables the systematic identification of knowledge gaps to generate research questions that strengthen intervention design. ToC may improve the evaluation of interventions by providing a comprehensive set of indicators to evaluate all stages of the causal pathway through which an intervention achieves impact, combining evaluations of intervention effectiveness with detailed process evaluations into one theoretical framework. Incorporating a ToC approach into the MRC framework holds promise for improving the design and evaluation of complex

  5. Theory of Change: a theory-driven approach to enhance the Medical Research Council's framework for complex interventions

    Science.gov (United States)

    2014-01-01

    Background The Medical Research Councils’ framework for complex interventions has been criticized for not including theory-driven approaches to evaluation. Although the framework does include broad guidance on the use of theory, it contains little practical guidance for implementers and there have been calls to develop a more comprehensive approach. A prospective, theory-driven process of intervention design and evaluation is required to develop complex healthcare interventions which are more likely to be effective, sustainable and scalable. Methods We propose a theory-driven approach to the design and evaluation of complex interventions by adapting and integrating a programmatic design and evaluation tool, Theory of Change (ToC), into the MRC framework for complex interventions. We provide a guide to what ToC is, how to construct one, and how to integrate its use into research projects seeking to design, implement and evaluate complex interventions using the MRC framework. We test this approach by using ToC within two randomized controlled trials and one non-randomized evaluation of complex interventions. Results Our application of ToC in three research projects has shown that ToC can strengthen key stages of the MRC framework. It can aid the development of interventions by providing a framework for enhanced stakeholder engagement and by explicitly designing an intervention that is embedded in the local context. For the feasibility and piloting stage, ToC enables the systematic identification of knowledge gaps to generate research questions that strengthen intervention design. ToC may improve the evaluation of interventions by providing a comprehensive set of indicators to evaluate all stages of the causal pathway through which an intervention achieves impact, combining evaluations of intervention effectiveness with detailed process evaluations into one theoretical framework. Conclusions Incorporating a ToC approach into the MRC framework holds promise for

  6. The Importance of Team Sex Composition in Team-Training Research Employing Complex Psychomotor Tasks.

    Science.gov (United States)

    Jarrett, Steven M; Glaze, Ryan M; Schurig, Ira; Arthur, Winfred

    2017-08-01

    The relationship between team sex composition and team performance on a complex psychomotor task was examined because these types of tasks are commonly used in the lab-based teams literature. Despite well-documented sex-based differences on complex psychomotor tasks, the preponderance of studies-mainly lab based-that use these tasks makes no mention of the sex composition of teams across or within experimental conditions. A sample of 123 four-person teams with varying team sex composition learned and performed a complex psychomotor task, Steal Beasts Pro PE. Each team completed a 5-hr protocol whereby they conducted several performance missions. The results indicated significant large mean differences such that teams with larger proportions of males had higher performance scores. These findings demonstrate the potential effect of team sex composition on the validity of studies that use complex psychomotor tasks to explore and investigate team performance-related phenomena when (a) team sex composition is not a focal variable of interest and (b) it is not accounted for or controlled. Given the proclivity of complex psychomotor action-based tasks used in lab-based team studies, it is important to understand and control for the impact of team sex composition on team performance. When team sex composition is not controlled for, either methodologically or statistically, it may affect the validity of the results in teams studies using these types of tasks.

  7. Expanding the Reach of Physics-Engaging Students in Interdisciplinary Research Involving complex, real-world situation

    Science.gov (United States)

    Bililign, Solomon

    2014-03-01

    Physics plays a very important role in most interdisciplinary efforts and can provide a solid foundation for students. Retention of students in STEM areas can be facilitated by enhanced interdisciplinary education and research since students are strongly attracted to research with societal relevance and show increasing enthusiasm about problems that have practical consequences. One such area of research is a collaborative Earth System Science. The Earth System is dynamic and complex. It is comprised of diverse components that interact. By providing students the opportunities to work in interdisciplinary groups on a problem that reflects a complex, real-world situation they can see the linkages between components of the Earth system that encompass climate and all its components (weather precipitation, temperature, etc.) and technology development and deployment of sensors and sensor networks and social impacts. By involving students in the creation of their own personalized professional development plan, students are more focused and engaged and are more likely to remain in the program.

  8. Protocol for the process evaluation of a complex intervention designed to increase the use of research in health policy and program organisations (the SPIRIT study).

    Science.gov (United States)

    Haynes, Abby; Brennan, Sue; Carter, Stacy; O'Connor, Denise; Schneider, Carmen Huckel; Turner, Tari; Gallego, Gisselle

    2014-09-27

    Process evaluation is vital for understanding how interventions function in different settings, including if and why they have different effects or do not work at all. This is particularly important in trials of complex interventions in 'real world' organisational settings where causality is difficult to determine. Complexity presents challenges for process evaluation, and process evaluations that tackle complexity are rarely reported. This paper presents the detailed protocol for a process evaluation embedded in a randomised trial of a complex intervention known as SPIRIT (Supporting Policy In health with Research: an Intervention Trial). SPIRIT aims to build capacity for using research in health policy and program agencies. We describe the flexible and pragmatic methods used for capturing, managing and analysing data across three domains: (a) the intervention as it was implemented; (b) how people participated in and responded to the intervention; and (c) the contextual characteristics that mediated this relationship and may influence outcomes. Qualitative and quantitative data collection methods include purposively sampled semi-structured interviews at two time points, direct observation and coding of intervention activities, and participant feedback forms. We provide examples of the data collection and data management tools developed. This protocol provides a worked example of how to embed process evaluation in the design and evaluation of a complex intervention trial. It tackles complexity in the intervention and its implementation settings. To our knowledge, it is the only detailed example of the methods for a process evaluation of an intervention conducted as part of a randomised trial in policy organisations. We identify strengths and weaknesses, and discuss how the methods are functioning during early implementation. Using 'insider' consultation to develop methods is enabling us to optimise data collection while minimising discomfort and burden for

  9. HPLC studies of aquatic humic compounds and complexes from the Drigg research site, Cumbria

    International Nuclear Information System (INIS)

    Smith, B.

    1992-01-01

    The work described in this report forms part of a multidisciplinary project, the broad objective of which is to study the ability of natural organic compounds present in groundwater to form mobile complexes with radionuclides. Other components of this work include the development of High Performance Liquid Chromatogaphic techniques (HPLC) to extract natural organic material from groundwater with minimal alteration, the separation of those organic fractions that complex with cations, and the development of geochemical speciation models to describe or predict metal binding. 17 Refs., 25 Figs., 4 Tabs

  10. The center for plant and microbial complex carbohydrates at the University of Georgia Complex Carbohydrate Research Center. Five-year report, September 15, 1987--December 31, 1992

    Energy Technology Data Exchange (ETDEWEB)

    Albersheim, Peter; Darvill, Alan

    1992-05-01

    The Complex Carbohydrate Research Center (CCRC) is the home of ten independent but complementary interdisciplinary research groups led by nine regular faculty and one adjunct faculty. The research of these groups represents a broad spectrum of interests, and they are involved in about 90 collaborations with their CCRC and UGA colleagues and with scientists at other institutions and companies in the US, Canada, Europe, Israel, and Japan. The hallmark of the CCRC is the collaborative, interactive environment encouraged by its directors, faculty and tong-term staff. Newcomers to the CCRC or short-term members soon learn that everyone benefits from this process. The team-oriented approach in carbohydrate science translates into the day-today generous giving of one's time and expertise to the work of others, whether it be in sharing specialized instrumentation, participating in the design of experiments and interpretalon of data, providing service to scientists outside the CCRC, or joining collaborative projects. The CCRC is founded on the principle that the cross-fertilization of ideas and know-how leads to the synergistic advancement of science. This report contains a series of appendices that document the extent and breadth of the Plant and Microbial Carbohydrate Center's contributions to collaborative research and education. Several collaborative research projects that have received postdoctoral research associate support from the Grant are highlighted, as these projects are particularly illustrative of the wide-ranging collaborations that have evolved as a result of this Grant and the quality of the science that the Grant enables.

  11. Research

    African Journals Online (AJOL)

    abp

    2017-11-24

    Nov 24, 2017 ... Page number not for citation purposes. 1. Prevalence and determinants of common mental ..... illnesses were smoke cigarette in the last 3 months that make prevalence of tobacco use 38.2%. ..... Okasha A, Karam E.Mental health services and research in the. Arab world. Acta Psychiatrica Scandinavica.

  12. Systems-Level Energy Audit for Main Complex, Construction Engineering Research Laboratory

    National Research Council Canada - National Science Library

    Lin, Mike

    2003-01-01

    ... (Buildings 1, 2, and 3) was conducted. The goals of the audit were to review energy and water use in the current main complex building, to review and inventory energy system equipment, and to devise short- and long-term energy improvement...

  13. The Oedipal Complex and Child Sexual Abuse Research: A Re-examination of Freud's Hypothesis.

    Science.gov (United States)

    Kendall-Tackett, Kathleen A.

    In 1896, Sigmund Freud stated that early childhood seduction caused hysteria in his female patients. He later recanted his original finding and claimed that the reports of abuse he heard from his patients were not descriptions of real events, but his patients' expressions of unconscious childhood wishes. The theory of the Oedipal complex gave…

  14. Researchers and stakeholders shape advances in management of tree and vine trunk-disease complexes

    Science.gov (United States)

    The grapevine trunk-disease complex limits grape production and vineyard longevity worldwide. Every vineyard in California eventually is infected by one or more trunk diseases. The causal fungi, which are taxonomically unrelated Ascomycetes, infect and then degrade the permanent woody structure of t...

  15. A Research on Wind Farm Micro-sitting Optimization in Complex Terrain

    DEFF Research Database (Denmark)

    Xu, Chang; Yang, Jianchuan; Li, Chenqi

    2013-01-01

    Wind farm layout optimization in complex terrain is a pretty difficult issue for onshore wind farm. In this article, a novel optimization method is proposed to optimize the layout for wind farms in complex terrain. This method utilized Lissaman and Jensen wake models for taking the terrain height...... that the CPSO method has a higher optimal value, and could be used to optimize the actual wind farm micro-sitting engineering projects.......Wind farm layout optimization in complex terrain is a pretty difficult issue for onshore wind farm. In this article, a novel optimization method is proposed to optimize the layout for wind farms in complex terrain. This method utilized Lissaman and Jensen wake models for taking the terrain height...... turbines’ park coordinates which subject to the boundary and minimum distance conditions between two wind turbines. A Cross Particle Swarm Optimization (CPSO) method is developed and applied to optimize the layout for a certain wind farm case. Compared with the uniform and experience method, results show...

  16. Aspects of Cognitive Complexity Theory and Research as Applied to a Managerial Decision Making Simulation

    Science.gov (United States)

    1985-09-01

    existence of at least a limited typography : Some degree of generality of cognitive style across domains was obtained. Which style is utilized in a...obtained results indicating that complexity is related to affect and dispersion of affect ratings for brands of toothpaste and automobiles. Specifically

  17. Software and hardware complex for research and management of the separation process

    Science.gov (United States)

    Borisov, A. P.

    2018-01-01

    The article is devoted to the development of a program for studying the operation of an asynchronous electric drive using vector-algorithmic switching of windings, as well as the development of a hardware-software complex for controlling parameters and controlling the speed of rotation of an asynchronous electric drive for investigating the operation of a cyclone. To study the operation of an asynchronous electric drive, a method was used in which the average value of flux linkage is found and a method for vector-algorithmic calculation of the power and electromagnetic moment of an asynchronous electric drive feeding from a single-phase network is developed, with vector-algorithmic commutation, and software for calculating parameters. The software part of the complex allows to regulate the speed of rotation of the motor by vector-algorithmic switching of transistors or, using pulse-width modulation (PWM), set any engine speed. Also sensors are connected to the hardware-software complex at the inlet and outlet of the cyclone. The developed cyclone with an inserted complex allows to receive high efficiency of product separation at various entrance speeds. At an inlet air speed of 18 m / s, the cyclone’s maximum efficiency is achieved. For this, it is necessary to provide the rotational speed of an asynchronous electric drive with a frequency of 45 Hz.

  18. Embracing Connectedness and Change: A Complex Dynamic Systems Perspective for Applied Linguistic Research

    Science.gov (United States)

    Cameron, Lynne

    2015-01-01

    Complex dynamic systems (CDS) theory offers a powerful metaphorical model of applied linguistic processes, allowing holistic descriptions of situated phenomena, and addressing the connectedness and change that often characterise issues in our field. A recent study of Kenyan conflict transformation illustrates application of a CDS perspective. Key…

  19. Survey and research of the latest works of LES about models near wall boundary and applications to complex flow path

    International Nuclear Information System (INIS)

    Sakai, Norio; Shimizu, Takeshi

    2005-02-01

    Since treatments for wall boundaries and flows around complex paths are issues in LES modeling, a literature research on the LES methods for wall boundaries and applications to flows at complex paths was conducted to investigate the latest trend. Publications of domestic or international societies, workshops, symposiums, and journals about for past 3 years (2001-2004) were searched and collected, from which 23 research papers were selected and investigated. For the investigation, the treatments for wall boundaries used in the literature were classified roughly into five methods, i.e. (1) no-slip condition, (2) algebraic wall model (wall function), (3) wall model based on boundary-layer approximations (differential equation wall model), (4) hybrid method, (5) immersed boundary method. No-slip conditions were widely applied in recent works. For algebraic wall models, new wall functions that considered the effect of the velocity component vertical to a wall or circulation regions were examined. There were also some researches that devised the process of calculating the wall-shear stress with a conventional wall function. The researches using differential equation wall models presented the dynamic modification of model coefficients, or the application of high-order turbulence model such as the k-e model to the solution of Navier-Stokes equation in the boundary layer. The researches of hybrid methods focused on the discontinuity of velocity and eddy viscosity at the LES/RANS interface. Several researches that adopted immersed boundary methods for Cartesian girds with curved wall boundaries introduced the investigation of the Poisson solvers and the numerical modification of pressure boundary conditions. Many of investigated researches used hybrid methods. Thus, it is expected that they will be mainly applied to large-scale and complex simulations if the standard treatment for the discontinuity at the interface is developed. (author)

  20. Research and development of system to utilize photovoltaic energy. Survey on the specific purpose modules; Taiyoko hatsuden riyo system no kenkyu kaihatsu. Taiyoto module ni kansuru chosa kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    Tatsuta, M [New Energy and Industrial Technology Development Organization, Tokyo (Japan)

    1994-12-01

    This paper reports the survey results on the specific purpose modules for photovoltaic power generation in fiscal 1994. (1) On the feasibility survey on new application fields, it was clarified that photovoltaic power generation is applicable to extensive areas such as farmland, road, railway and public facility as latent demand sites. (2) On the optimum modules for various specific purposes, the structure, production method, cost estimation and issues of various modules were studied for desert, wasteland, coast, ocean, river, embankment, railway, road, mobile facility and arcade. (3) On the survey on new materials and material development, various conventional materials and materials promising for required performance were surveyed for every application. (4) On the survey on technology trends, the survey members participated in the first international photovoltaic energy conversion conference and the photovoltaic power generation workshop, while the members held the 1st-5th specific purpose module subcommittees. 1 tab.

  1. JENDL special purpose file

    International Nuclear Information System (INIS)

    Nakagawa, Tsuneo

    1995-01-01

    In JENDL-3,2, the data on all the reactions having significant cross section over the neutron energy from 0.01 meV to 20 MeV are given for 340 nuclides. The object range of application extends widely, such as the neutron engineering, shield and others of fast reactors, thermal neutron reactors and nuclear fusion reactors. This is a general purpose data file. On the contrary to this, the file in which only the data required for a specific application field are collected is called special purpose file. The file for dosimetry is a typical special purpose file. The Nuclear Data Center, Japan Atomic Energy Research Institute, is making ten kinds of JENDL special purpose files. The files, of which the working groups of Sigma Committee are in charge, are listed. As to the format of the files, ENDF format is used similarly to JENDL-3,2. Dosimetry file, activation cross section file, (α, n) reaction data file, fusion file, actinoid file, high energy data file, photonuclear data file, PKA/KERMA file, gas production cross section file and decay data file are described on their contents, the course of development and their verification. Dosimetry file and gas production cross section file have been completed already. As for the others, the expected time of completion is shown. When these files are completed, they are opened to the public. (K.I.)

  2. Participatory Action Research with "Minority Communities" and the Complexities of Emancipatory Tensions: Intersectionality and Cultural Affinity

    Science.gov (United States)

    Sallah, Momodou

    2014-01-01

    Conducting research with communities constructed as the "other" from a purely positivist paradigm can often be replete with colossal flaws with enormous potential to oppress the researched--especially minority communities in this case. This article presents an analysis of the cultural and experiential affinity experiences of the author…

  3. Child Sexual Abuse at Preschools--A Research Review of a Complex Issue for Preschool Professionals

    Science.gov (United States)

    Bergström, Helena; Eidevald, Christian; Westberg-Broström, Anna

    2016-01-01

    The objective of this research review is to synthesize research published between 2000 and 2015 regarding child sexual abuse, preschool and preschool teachers. The review identifies themes relevant for the preschool teacher profession: child sexual abuse at preschools, suspicions and consequences for the preschool sector, preventing techniques and…

  4. Psychotherapy and Outcome Research in PTSD: Understanding the Challenges and Complexities in the Literature

    Science.gov (United States)

    Black, Timothy G.

    2004-01-01

    The author reviews the existing literature on posttraumatic stress disorder (PTSD, American Psychiatric Association, 2000) as it relates to outcome research and psychotherapy. An initial examination of the issues involved in outcome research includes the issue of assessment and diagnosis, followed by the issue of measurement. The article is meant…

  5. Navigating the Complexity of Qualitative Research in Postmodern Contexts: Assemblage, Critical Reflexivity, and Communion as Guides

    Science.gov (United States)

    Bettez, Silvia Cristina

    2015-01-01

    For graduate students and other emerging qualitative researchers, the ever-evolving and sometimes conflicting perspectives, methodologies, and practices within various post-positivist frameworks (e.g. feminist, critical, Indigenous, participatory) can be overwhelming. Qualitative researchers working within postmodern contexts of multiplicity and…

  6. Complexity, Accuracy, Fluency and Lexis in Task-Based Performance: A Synthesis of the Ealing Research

    Science.gov (United States)

    Skehan, Peter; Foster, Pauline

    2012-01-01

    This chapter will present a research synthesis of a series of studies, termed here the Ealing research. The studies use the same general framework to conceptualise tasks and task performance, enabling easier comparability. The different studies, although each is self-contained, build into a wider picture of task performance. The major point of…

  7. Research on a scheduling mechanism in a complex system based on TOC

    International Nuclear Information System (INIS)

    Wen, Zhang; Ya-Ming, Zhang; Jinbo, Chen; Kaijun, Leng

    2016-01-01

    Under the condition where there is no seasonal demand fluctuation, short life cycle product supply chain should confront the market environment such as the decreasing of product value, the launch of substitutes and the appearance of competitors’ similar products, and the supply chain will become a very complex system. In this paper, the authors consider a TOC-based scheduling mechanism in this complex supply chain system. under the constant total production cost, it is more important to improve the availability of the wanted product in order to enhance the overall supply chain competitiveness so to obtain more effective output(profit rate) for the supply chain in a long period. Especially we try to apply the SDBR concept into a schedule mechanism in a particular supply chain system, and use numerical analysis to test the efficiency of the proposed method.

  8. Research on the Complexity of Dual-Channel Supply Chain Model in Competitive Retailing Service Market

    Science.gov (United States)

    Ma, Junhai; Li, Ting; Ren, Wenbo

    2017-06-01

    This paper examines the optimal decisions of dual-channel game model considering the inputs of retailing service. We analyze how adjustment speed of service inputs affect the system complexity and market performance, and explore the stability of the equilibrium points by parameter basin diagrams. And chaos control is realized by variable feedback method. The numerical simulation shows that complex behavior would trigger the system to become unstable, such as double period bifurcation and chaos. We measure the performances of the model in different periods by analyzing the variation of average profit index. The theoretical results show that the percentage share of the demand and cross-service coefficients have important influence on the stability of the system and its feasible basin of attraction.

  9. Modelling of ion sorption on complex solid materials. Synthesis of research activities

    International Nuclear Information System (INIS)

    Marmier, Nicolas

    2000-01-01

    In this HDR (Accreditation to Supervise Researches) report, the author proposes an overview of his research activities which are part of efforts of qualification and quantification of retention capacities of synthetic and artificial materials used to confine nuclear wastes in an underground geological site by absorption of radio-elements possibly passed into solution. More specifically, these research works focused on models aimed at predicting the behaviour of a mixing with respect to adsorption, and thus at avoiding too cumbersome experimental characterizations. The author presents the designed modelling approach and models, describes the implemented scientific approach and the associated data acquisition methodology, and discusses the obtained results. He finally proposed an assessment of these research works, and discusses research perspectives on a short and medium term [fr

  10. Speleomycological research in underground Osówka complex in Sowie Mountains (Lower Silesia, Poland

    Directory of Open Access Journals (Sweden)

    Wojciech Pusz

    2014-01-01

    Full Text Available Osówka (Germ. Säuferhöhen, is one of the elements of the unfinished Nazi military complex called “Riese”. The total length of corridors of Osówka complex is about 1,700 m and its capacity amounts to 30,000 m3. As described geologically, Osówka is situated within the Sowie Mts. Massif which consists mostly of various gneisses with different structural characteristics, but with a constant mineral composition. The rock-forming minerals are feldspar (oligoclase, quartz, biotite and light micas, accesory minerals are garnet, sillimanite and dysten. Fine-grained shallow-sea deposits were probably a protolith of these rocks. The study aimed at first mycological evaluation of the air and the rocks in Osówka adit. The air samples were taken from one location outside the adit and from four locations inside of it. Mycological evaluation of the rocks inside the adit was performed using three different methods. Fifteen taxa of filamentous fungi were isolated from the internal air sampled, and several taxa - from the outside of the adit, whereas only eleven species were isolated from the rocks. Cladosporium spp. were the fungi most frequently isolated from internal atmosphere of the underground Osówka complex, and from the external air. On the other hand, the fungi most frequently isolated from the rocks were Aspergillus niger group (when using swab sampling procedure and Mucor spp. (from debris and rinse sampling procedure.

  11. Research on evaluation of degree of complexity of mining fault network based on GIS

    Energy Technology Data Exchange (ETDEWEB)

    Hua Zhang; Yun-jia Wang; Chuan-zhi Liu [China University of Mining and Technology, Jiangsu (China). School of Environment Science and Spatial Informatics

    2007-03-15

    A large number of spatial and attribute data are involved in coal resource evaluation. Databases are a relatively advanced data management technology, but their major defects are the poor graphic and spatial data functions, from which it is difficult to realize scientific management of evaluation data with spatial characteristics and evaluation result maps. On account of these deficiencies, the evaluation of degree of complexity of mining fault network based on a geographic information system (GIS) is proposed which integrates management of spatial and attribute data. A fractal is an index which can reflect the comprehensive information of faults' number, density, size, composition and dynamics mechanism. A fractal dimension is used as the quantitative evaluation index. Evaluation software has been developed based on a component GIS-MapX, with which the degree of complexity of fault network is evaluated quantitatively using the quantitative index of fractal dimensions in Liuqiao No.2 coal mine as an example. Results show that it is effective in acquiring model parameters and enhancing the definition of data and evaluation results with the application of GIS technology. The fault network is a system with fractal structure and its complexity can be described reasonably and accurately by fractal dimension, which provides an effective method for coal resource evaluation. 9 refs., 6 figs., 2 tabs.

  12. Research activities of MPA, Stuttgart University, for enhanced safety and reliability of components under complex load

    International Nuclear Information System (INIS)

    Herter, K.H.; Roos, E.; Schuler, X.; Maile, K.

    2004-01-01

    MPA research activities focus on fracture prevention and on the development of a generally applicable method of component integrity testing which, independent of the safety relevance of the components involved, is also part of ageing management. (orig.) [de

  13. A complex process - transforming scientific research into regulatory rules for environmental protection

    International Nuclear Information System (INIS)

    Yan, J.J.; Goss, D.; Huffman, A.

    2002-01-01

    The protection of isolated wetlands from consumptive use withdrawals has been a policy in the South Florida Water Management District (SFWMD) for over 15 years. A guideline for protecting isolated wetlands was established in the mid-1980's for the consumptive water use permitting program administered by the SFWMD. The guideline specifies groundwater drawdown criteria associated with well field pumpage. In 1994, the SFWMD convened a panel of wetland scientists to review the existing groundwater drawdown criteria. The panel concluded there was insufficient information to determine if the criteria were either too restrictive or insufficient in protecting wetlands. The panel recommended that the SFWMD conduct research to answer related questions. Since that time, staff at the SFWMD have developed a research plan, selected 38 isolated wetland monitoring sites in seven study areas, collected over four years of data, and developed an integrated surface water and groundwater simulation model. However, the staff at the SFWMD has had difficulties in transforming the research results into regulatory rules. The nature of an isolated wetland is quite complicated. Its setting changes significantly from time to time depending on the variation of rainfall, hydro-geological conditions, and human activities. A regulatory rule requires simple and more easily measurable criteria. The regulatory staff need simple tools to evaluate many permit applications within a limited time frame. The tools used in the research process are often complicated and time consuming. This paper describes the wetland research, and the difficulties of transforming research results into regulatory rules. (author)

  14. Enacting Kaitiakitanga: Challenges and Complexities in the Governance and Ownership of Rongoā Research Information

    Directory of Open Access Journals (Sweden)

    Amohia Boulton

    2014-04-01

    Full Text Available This article explores the tensions one research team has faced in securing appropriate governance or stewardship (which we refer to as kaitiakitanga of research data. Whilst ethical and regulatory frameworks exist which provide a minimum standard for researchers to meet when working with Māori, what our experience has highlighted is there is currently a “governance” gap in terms of who should hold stewardship of research data collected from Māori individuals or collectives. In the case of a project undertaken in the traditional healing space, the organisation best placed to fulfil this governance role receives no funding or support to take on such a responsibility; consequently by default, this role is being borne by the research team until such time as capacity can be built and adequate resourcing secured. In addition, we have realised that the tensions played out in this research project have implications for the broader issue of how we protect traditional knowledge in a modern intellectual property law context, and once again how we adequately support those, often community-based organisations, who work at the interface between Indigenous knowledge and the Western world.

  15. Identification of global oil trade patterns: An empirical research based on complex network theory

    International Nuclear Information System (INIS)

    Ji, Qiang; Zhang, Hai-Ying; Fan, Ying

    2014-01-01

    Highlights: • A global oil trade core network is analyzed using complex network theory. • The global oil export core network displays a scale-free behaviour. • The current global oil trade network can be divided into three trading blocs. • The global oil trade network presents a ‘robust and yet fragile’ characteristic. - Abstract: The Global oil trade pattern becomes increasingly complex, which has become one of the most important factors affecting every country’s energy strategy and economic development. In this paper, a global oil trade core network is constructed to analyze the overall features, regional characteristics and stability of the oil trade using complex network theory. The results indicate that the global oil export core network displays a scale-free behaviour, in which the trade position of nodes presents obvious heterogeneity and the ‘hub nodes’ play a ‘bridge’ role in the formation process of the trade network. The current global oil trade network can be divided into three trading blocs, including the ‘South America-West Africa-North America’ trading bloc, the ‘Middle East–Asian–Pacific region’ trading bloc, and ‘the former Soviet Union–North Africa–Europe’ trading bloc. Geopolitics and diplomatic relations are the two main reasons for this regional oil trade structure. Moreover, the global oil trade network presents a ‘robust but yet fragile’ characteristic, and the impacts of trade interruption always tend to spread throughout the whole network even if the occurrence of export disruptions is localised

  16. Operation modes research of liquefied natural gas storages as a part of the ground complexes equipment

    Directory of Open Access Journals (Sweden)

    N. S. Korolev

    2014-01-01

    Full Text Available The use of the Liquefied Natural Gas (LNG in the space-rocket equipment is motivated by some advantages. That is why a lot of tests and works are actively carried out now on rocket engines using liquefied natural gas.To provide the engine tests and subsequent rocket complex operation a creation of LNG storages is demanded as a part of ground processing equipment and support for their safe operation conditions.One of LNG danger factor is its low boiling temperature, and also changing the condition, density and LNG boiling temperature at storage due to evaporation of light component, namely methane. At refill of the storages having fuel remains with a new LNG portion these factors can lead to formation of the stratified macro-layers and cause a mode of the intensive mixing that is called "rollover", with almost instant evaporation of LNG big mass and sharp pressure boost, capable to result in the storage distraction with catastrophic effects.The work objectives are formulated such as a technique development for forecasting of the LNG parameters in operating storages including the rollover mode, a comparison of calculated results of the LNG parameters with the experimental data, and a definition of possible recommendations for safe operation of LNG storages as a part of the ground complexes equipment.The paper reviews 12 publications concerning the issues and proceeding processes at operation of LNG storages, including the rollover mode.To verify the reliability of process simulation results in the LNG, represented in models by the binary methane-ethane mixture the calculated values have been compared with the experimental data for a LNG storage mode in the reservoir of a ground test complex.The reliability of developed models of the heat-mass-exchange processes in stratified on density and temperature in LNG storage with emergence of conditions for the rollover mode has been verified by comparing the settlement characteristics to the published

  17. Collaborative Observation and Research (CORE) Watersheds: new strategies for tracking the regional effects of climate change on complex systems

    Science.gov (United States)

    Murdoch, P. S.

    2007-12-01

    The past 30 years of environmental research have shown that our world is not made up of discrete components acting independently, but rather of a mosaic of complex relations among air, land, water, living resources, and human activities. Recent warming of the climate is having a significant effect on the functioning of those systems. A national imperative is developing to quickly establish local, regional, and national systems for anticipating environmental degradation from a changing climate and developing cost-effective adaptation or mitigation strategies. In these circumstances, the debate over research versus monitoring becomes moot--there is a clear need for the integrated application of both across a range of temporal and spatial scales. A national framework that effectively addresses the multiple scales and complex multi-disciplinary processes of climate change is being assembled largely from existing programs through collaboration among Federal, State, local, and NGO organizations. The result will be an observation and research network capable of interpreting complex environmental changes at a range of spatial and temporal scales, but at less cost than if the network were funded as an independent initiative. A pilot implementation of the collaborative framework in the Delaware River Basin yielded multi-scale assessments of carbon storage and flux, and the effects of forest fragmentation and soil calcium depletion on ecosystem function. A prototype of a national climate-effects observation and research network linking research watersheds, regional surveys, remote sensing, and ecosystem modeling is being initiated in the Yukon River Basin where carbon flux associated with permafrost thaw could accelerate global warming.

  18. Validity of silhouette showcards as a measure of body size and obesity in a population in the African region: A practical research tool for general-purpose surveys.

    Science.gov (United States)

    Yepes, Maryam; Viswanathan, Barathi; Bovet, Pascal; Maurer, Jürgen

    2015-01-01

    The purpose of this study is to validate the Pulvers silhouette showcard as a measure of weight status in a population in the African region. This tool is particularly beneficial when scarce resources do not allow for direct anthropometric measurements due to limited survey time or lack of measurement technology in face-to-face general-purpose surveys or in mailed, online, or mobile device-based surveys. A cross-sectional study was conducted in the Republic of Seychelles with a sample of 1240 adults. We compared self-reported body sizes measured by Pulvers' silhouette showcards to four measurements of body size and adiposity: body mass index (BMI), body fat percent measured, waist circumference, and waist to height ratio. The accuracy of silhouettes as an obesity indicator was examined using sex-specific receiver operator curve (ROC) analysis and the reliability of this tool to detect socioeconomic gradients in obesity was compared to BMI-based measurements. Our study supports silhouette body size showcards as a valid and reliable survey tool to measure self-reported body size and adiposity in an African population. The mean correlation coefficients of self-reported silhouettes with measured BMI were 0.80 in men and 0.81 in women (P general-purpose surveys of obesity in social sciences, where limited resources do not allow for direct anthropometric measurements.

  19. The center for plant and microbial complex carbohydrates at the University of Georgia Complex Carbohydrate Research Center. Annual report, September 15, 1990--December 31, 1991

    Energy Technology Data Exchange (ETDEWEB)

    Albersheim, P.; Darvill, A.

    1991-08-01

    Research from the Complex Carbohydrates Research Center at the University of Georgia is presented. Topics include: Structural determination of soybean isoflavones which specifically induce Bradyrhizobium japonicum nodD1 but not the nodYABCSUIJ operon; structural analysis of the lipopolysaccharides (LPSs) from symbiotic mutants of Bradyrhizobium japonicum; structural characterization of lipooligosaccharides from Bradyrhizobium japonicum that are required for the specific nodulation of soybean; structural characterization of the LPSs from R. Leguminosarum biovar phaseoli, the symbiont of bean; characterization of bacteroid-specific LPS epitopes in R. leguminosarum biovar viciae; analysis of the surface polysaccharides of Rhizobium meliloti mutants whose lipopolysaccharides and extracellular polysaccharides can have the same function in symbiosis; characterization of a polysaccharide produced by certain Bradyrhizobium japonicum strains within soybean nodules; structural analysis of a streptococcal adhesin polysaccharide receptor; conformational studies of xyloglucan, the role of the fucosylated side chain in surface-specific cellulose-xyloglucan interactions; the structure of an acylated glucosamine oligosaccharide signal molecule (nod factor) involved in the symbiosis of Rhizobium leguminosarum biovar viciae with its host Vicia sativa; investigating membrane responses induced by oligogalacturonides in cultured cells; the polygalacturonase inhibitor protein; characterization of the self-incompatability glycoproteins from Petunia hybrida; investigation of the cell wall polysaccharide structures of Arabidopsis thaliana; and the glucan inhibition of virus infection of tabacco.

  20. Participatory Ethnographic Evaluation and Research: Reflections on the Research Approach Used to Understand the Complexity of Maternal Health Issues in South Sudan.

    Science.gov (United States)

    Elmusharaf, Khalifa; Byrne, Elaine; Manandhar, Mary; Hemmings, Joanne; O'Donovan, Diarmuid

    2017-07-01

    Many methodological approaches have been used to understand cultural dimensions to maternal health issues. Although a well-designed quantitative survey with a representative sample can provide essential information on trends in behavior, it does not necessarily establish a contextualized understanding of the complexity in which different behaviors occur. This article addresses how contextualized data can be collected in a short time and under conditions in which participants in conflict-affected zones might not have established, or time to establish, trust with the researchers. The solution, the Participatory Ethnographic Evaluation and Research (PEER) approach, is illustrated through a study whereby South Sudanese marginalized women were trained to design research instruments, and collect and analyze qualitative data. PEER overcomes the problem that many ethnographic or participatory approaches face-the extensive time and resources required to develop trusting relationships with the community to understand the local context and the social networks they form.

  1. Research on the EDM Technology for Micro-holes at Complex Spatial Locations

    Science.gov (United States)

    Y Liu, J.; Guo, J. M.; Sun, D. J.; Cai, Y. H.; Ding, L. T.; Jiang, H.

    2017-12-01

    For the demands on machining micro-holes at complex spatial location, several key technical problems are conquered such as micro-Electron Discharge Machining (micro-EDM) power supply system’s development, the host structure’s design and machining process technical. Through developing low-voltage power supply circuit, high-voltage circuit, micro and precision machining circuit and clearance detection system, the narrow pulse and high frequency six-axis EDM machining power supply system is developed to meet the demands on micro-hole discharging machining. With the method of combining the CAD structure design, CAE simulation analysis, modal test, ODS (Operational Deflection Shapes) test and theoretical analysis, the host construction and key axes of the machine tool are optimized to meet the position demands of the micro-holes. Through developing the special deionized water filtration system to make sure that the machining process is stable enough. To verify the machining equipment and processing technical developed in this paper through developing the micro-hole’s processing flow and test on the real machine tool. As shown in the final test results: the efficient micro-EDM machining pulse power supply system, machine tool host system, deionized filtration system and processing method developed in this paper meet the demands on machining micro-holes at complex spatial locations.

  2. Research based teaching as a model for developing complex pre-cast concrete structures

    DEFF Research Database (Denmark)

    Egholm Pedersen, Ole

    2012-01-01

    master students assisted in the development and realisation of an amorphous, catenary grid-shell. Development in many areas simultaneously was essential for the success of the case studies, which made them suitable for a research-based teaching setup, where didactic considerations on a general...... and specific level were important: On a general level, three didactic tools were used: the first being the presentation of knowledge generation as something that happens between researcher and student. The second involved presenting students with a narrow focus before presenting a wide one, and the third......: viewing the teaching studio as an interdisciplinary laboratory. On a specific level, didactic considerations involved a division of responsibility into smaller areas of investigation, allowing the students to conduct relevant experimentation while negotiating other areas of the research. Also...

  3. Health Systems Research in a Complex and Rapidly Changing Context: Ethical Implications of Major Health Systems Change at Scale.

    Science.gov (United States)

    MacGregor, Hayley; Bloom, Gerald

    2016-12-01

    This paper discusses health policy and systems research in complex and rapidly changing contexts. It focuses on ethical issues at stake for researchers working with government policy makers to provide evidence to inform major health systems change at scale, particularly when the dynamic nature of the context and ongoing challenges to the health system can result in unpredictable outcomes. We focus on situations where 'country ownership' of HSR is relatively well established and where there is significant involvement of local researchers and close ties and relationships with policy makers are often present. We frame our discussion around two country case studies with which we are familiar, namely China and South Africa and discuss the implications for conducting 'embedded' research. We suggest that reflexivity is an important concept for health system researchers who need to think carefully about positionality and their normative stance and to use such reflection to ensure that they can negotiate to retain autonomy, whilst also contributing evidence for health system change. A research process informed by the notion of reflexive practice and iterative learning will require a longitudinal review at key points in the research timeline. Such review should include the convening of a deliberative process and should involve a range of stakeholders, including those most likely to be affected by the intended and unintended consequences of change. © 2016 The Authors Developing World Bioethics Published by John Wiley & Sons Ltd.

  4. The Hsp90 Complex in Microbes and Man | Center for Cancer Research

    Science.gov (United States)

    Why would cancer researchers be interested in how a bacteria named Escherichia coli (E. coli) rebuilds its cellular proteins after they have been inactivated by environmental stress such as heat?  The answer lies in a protein remodeling mechanism that is shared by microbes and man.

  5. Going beyond Procedure: Engaging with the Ethical Complexities of Being an Embedded Researcher

    Science.gov (United States)

    Rowley, Harriet

    2014-01-01

    This article is a reflection upon the ethical dimension of my work and practice as an embedded researcher during my doctorate. To begin with, I describe my experiences of gaining ethical approval from The University of Manchester while also highlighting some of the concerns that were raised by the ethics board. This leads me to recognise how the…

  6. Enriching Gender in Physics Education Research: A Binary Past and a Complex Future

    Science.gov (United States)

    Traxler, Adrienne L.; Cid, Ximena C.; Blue, Jennifer; Barthelemy, Ramón

    2016-01-01

    In this article, we draw on previous reports from physics, science education, and women's studies to propose a more nuanced treatment of gender in physics education research (PER). A growing body of PER examines gender differences in participation, performance, and attitudes toward physics. We have three critiques of this work: (i) it does not…

  7. "Knowledge Must Be Contextual": Some Possible Implications of Complexity and Dynamic Systems Theories for Educational Research

    Science.gov (United States)

    Haggis, Tamsin

    2008-01-01

    It is now widely accepted that qualitative and quantitative research traditions, rather than being seen as opposed to or in competition with each other (Hammersley & Atkinson, 1995; Furlong, 2004 ) should be used, where appropriate, in some kind of combination (Bryman & Cramer, 1999; Moore et al., 2003 ). How this combining is to be understood…

  8. Increasing Complexity of Clinical Research in Gastroenterology: Implications for Training Clinician-Scientists

    Science.gov (United States)

    Scott, Frank I.; McConnell, Ryan A.; Lewis, Matthew E.; Lewis, James D.

    2014-01-01

    Background Significant advances have been made in clinical and epidemiologic research methods over the past 30 years. We sought to demonstrate the impact of these advances on published research in gastroenterology from 1980 to 2010. Methods Three journals (Gastroenterology, Gut, and American Journal of Gastroenterology) were selected for evaluation given their continuous publication during the study period. Twenty original clinical articles were randomly selected from each journal from 1980, 1990, 2000, and 2010. Each article was assessed for topic studied, whether the outcome was clinical or physiologic, study design, sample size, number of authors and centers collaborating, and reporting of statistical methods such as sample size calculations, p-values, confidence intervals, and advanced techniques such as bioinformatics or multivariate modeling. Research support with external funding was also recorded. Results A total of 240 articles were included in the study. From 1980 to 2010, there was a significant increase in analytic studies (pgastroenterology and hepatology over the last three decades. This increase highlights the need for advanced training of clinical investigators to conduct future research. PMID:22475957

  9. Responding to complex societal challenges: A decade of Earth System Science Partnership (ESSP) interdisciplinary research

    NARCIS (Netherlands)

    Ignaciuk, A.; Rice, M.; Bogardi, J.; Canadell, J.G.; Dhakal, S.; Ingram, J.; Leemans, R.; Rosenberg, M.

    2012-01-01

    The Earth system is an integrated, self-regulating system under increasing pressure from anthropogenic transformation. The Earth System Science Partnership (ESSP), which was established by the international global environmental change research programs (i.e., DIVERSITAS, IGBP, IHDP and WCRP)

  10. Role of complex utilization of mineral raw materials In geological research

    Energy Technology Data Exchange (ETDEWEB)

    Takacs, P.; Varju, G.

    1979-01-01

    Presents Hungarian research efforts on ways of utilizing the secondary raw materials alunite, pumice and slate coal from various mines. The slate coal is separated from brown coal and disposed of at spoil banks of brown coal mines, due to its high ash content (up to 56.8% under dry conditions), silicate content up to 58.2% and low calorific value between 1500 and 2780 kcal/kg. The research proposal for utilizing slate coal is directed at partial separation of the mineral and coal content by comminution, peptization and hydrocentrifugal separation. The larger part of the silicate content is held in the colloid suspension, which could be used for conditioning drilling mud or foundry sand. The produced coal concentrate has a reduced ash content and higher calorific value (between 500 and 800 kcal/kg) and could be employed in soil amelioration or combustion. (10 refs.) (In German)

  11. [Research in ethnobotany and the return of systematized knowledge to the community: a complex issue].

    Science.gov (United States)

    Patzlaff, Rubia Graciela; Peixoto, Ariane Luna

    2009-01-01

    How should information gathered in ethnobotanical research be returned to the social environment where it was generated? What should be taken to the community? These questions motivated the accompaniment of two ethnobotanical studies and their respective proposals for how to return to the community the knowledge associated to plants, systematized by the scientist. It is common for research data to be returned to a community by means of manuals, information booklets, illustrated lists of plants, lectures and courses. Nevertheless, other forms have been prepared that characterize an exchange of knowledge among the scientist and the community, with mutual gains. This study corroborates these alternatives and suggests that the definition of the activities to return knowledge to the community, even that proposed and agreed to at the beginning of the study, be flexible, allowing the inclusion of new needs that arise during the execution of the study.

  12. Is there a role for the lexis-grammar interface in interlanguage complexity research?

    OpenAIRE

    Paquot, Magali; Colloquium on cross-linguistic aspects of complexity in second language research

    2014-01-01

    A major contribution of recent research in theoretical linguistics, corpus linguistics and psycholinguistics has been to provide convergent evidence that lexis and grammar are closely intertwined (Sinclair, 1991; Stefanowitsch & Gries, 2003; Goldberg, 2006, Ellis & Cadierno, 2009; Römer, 2009). It has also been convincingly demonstrated that language is essentially made up of word combinations that constitute single choices and that words acquire meanings from their context (Sinclair, 1991; B...

  13. Process evaluation for complex interventions in health services research: analysing context, text trajectories and disruptions.

    Science.gov (United States)

    Murdoch, Jamie

    2016-08-19

    Process evaluations assess the implementation and sustainability of complex healthcare interventions within clinical trials, with well-established theoretical models available for evaluating intervention delivery within specific contexts. However, there is a need to translate conceptualisations of context into analytical tools which enable the dynamic relationship between context and intervention implementation to be captured and understood. In this paper I propose an alternative approach to the design, implementation and analysis of process evaluations for complex health interventions through a consideration of trial protocols as textual documents, distributed and enacted at multiple contextual levels. As an example, I conduct retrospective analysis of a sample of field notes and transcripts collected during the ESTEEM study - a cluster randomised controlled trial of primary care telephone triage. I draw on theoretical perspectives associated with Linguistic Ethnography to examine the delivery of ESTEEM through staff orientation to different texts. In doing so I consider what can be learned from examining the flow and enactment of protocols for notions of implementation and theoretical fidelity (i.e. intervention delivered as intended and whether congruent with the intervention theory). Implementation of the triage intervention required staff to integrate essential elements of the protocol within everyday practice, seen through the adoption and use of different texts that were distributed across staff and within specific events. Staff were observed deploying texts in diverse ways (e.g. reinterpreting scripts, deviating from standard operating procedures, difficulty completing decision support software), providing numerous instances of disruption to maintaining intervention fidelity. Such observations exposed tensions between different contextual features in which the trial was implemented, offering theoretical explanations for the main trial findings. The value of

  14. 3D Dynamic Modeling of the Head-Neck Complex for Fast Eye and Head Orientation Movements Research

    Directory of Open Access Journals (Sweden)

    Daniel A. Sierra

    2011-01-01

    Full Text Available A 3D dynamic computer model for the movement of the head-neck complex is presented. It incorporates anatomically correct information about the diverse elements forming the system. The skeleton is considered as a set of interconnected rigid 3D bodies following the Newton-Euler laws of movement. The muscles are modeled using Enderle's linear model, which shows equivalent dynamic characteristics to Loeb's virtual muscle model. The soft tissues, namely, the ligaments, intervertebral disks, and facet joints, are modeled considering their physiological roles and dynamics. In contrast with other head and neck models developed for safety research, the model is aimed to study the neural control of the complex during fast eye and head movements, such as saccades and gaze shifts. In particular, the time-optimal hypothesis and the feedback control ones are discussed.

  15. Experimental research of ZrO{sub 2}/BCP/PCL scaffold with complex pore pattern for bone tissue

    Energy Technology Data Exchange (ETDEWEB)

    Sa, Min Woo; Shin, Hae Ri; Kim, Jong Young [Dept. of Mechanical Engineering, Andong National University, Andong (Korea, Republic of)

    2015-11-15

    Recently, synthetic biopolymers and bioceramics such as poly (-caprolactone)(PCL), hydroxyapatite, tricalcium phosphate, biphasic calcium phosphate(BCP), and zirconia have been used as substrates to generate various tissues or organs in tissue engineering. Thus, the purpose of this study was the characterization of ZrO{sub 2}/BCP/PCL(ZBP) scaffold for bone tissue regeneration. Based on the result of single-line test, blended 3D ZBP scaffolds with fully interconnected pores and new complex pore pattern of -type and staggered-type were successfully fabricated using a polymer deposition system. Furthermore, the effect of ZBP scaffold on mechanical property was analyzed. In addition, in vitro cell interaction of ZBP scaffold on MG63 cells was evaluated using a cell counting kit-8(CCK-8) assay.

  16. Understanding complexities of synaptic transmission in medically intractable seizures: A paradigm of epilepsy research

    Directory of Open Access Journals (Sweden)

    Jyotirmoy Banerjee

    2013-01-01

    Full Text Available Investigating the changes associated with the development of epileptic state in humans is complex and requires a multidisciplinary approach. Understanding the intricacies of medically intractable epilepsy still remains a challenge for neurosurgeons across the world. A significant number of patients who has undergone resective brain surgery for epilepsy still continue to have seizures. The reason behind this therapy resistance still eludes us. Thus to develop a cure for the difficult to treat epilepsy, we need to comprehensively study epileptogenesis. Although various animal models are developed but none of them replicate the pathological conditions in humans. So the ideal way to understand epileptogenecity is to examine the tissue resected for the treatment of intractable epilepsy. Advanced imaging and electrical localization procedures are utilized to establish the epileptogenic zone in epilepsy patients. Further molecular and cytological studies are required for the microscopic analysis of brain samples collected from the epileptogenic focus. As alterations in inhibitory as well as excitatory synaptic transmission are key features of epilepsy, understanding the regulation of neurotransmission in the resected surgery zone is of immense importance. Here we summarize various modalities of in vitro slice analysis from the resected brain specimen to understand the changes in GABAergic and glutamatergic synaptic transmission in epileptogenic zone. We also review evidence pertaining to the proposed role of nicotinic receptors in abnormal synaptic transmission which is one of the major causes of epileptiform activity. Elucidation of current concepts in regulation of synaptic transmission will help develop therapies for epilepsy cases that cannot me managed pharmacologically.

  17. The research on the buried public monumental complexes of Lupiae (Lecce) by geophysical prospecting

    Science.gov (United States)

    Leucci, Giovanni; De Giorgi, Lara; Di Giacomo, Giacomo; Ditaranto, Imma; Miccoli, Ilaria; Scardozzi, Giuseppe

    2017-10-01

    Ongoing and extensive urbanisation may threaten important archaeological structures that are still buried in urban areas. The ground penetrating radar (GPR) method is the most promising alternative for resolving buried archaeological structures in urban territories. This paper presents a case study that involves a geophysical survey employing the surface three-dimensional (3D) GPR techniques, in order to archaeologically characterise the investigated areas. The site is located in the south-western sector of the historical centre of Lecce (Apulia, Italy), where the modern city overlaps the main public monuments of the Roman municipium of Lupiae, only partially preserved or excavated: the amphitheatre, the theatre, the baths and maybe also the Forum. GPR measurements, integrated with the results of archaeological excavations and the topographical surveys of the preserved remains, were carried out in several areas regarding sectors of the ancient roman city. The GPR data were collected along a dense network of parallel profiles. The GPR sections were processed applying specific filters to the data in order to enhance their information content. The GPR images significantly contributed in reconstructing the complex subsurface properties in these modern urban areas. Strong GPR reflections features were correlated with possible ancient structures and they were integrated in the digital archaeological map of the city.

  18. Research on lossless compression of true color RGB image with low time and space complexity

    Science.gov (United States)

    Pan, ShuLin; Xie, ChengJun; Xu, Lin

    2008-12-01

    Eliminating correlated redundancy of space and energy by using a DWT lifting scheme and reducing the complexity of the image by using an algebraic transform among the RGB components. An improved Rice Coding algorithm, in which presents an enumerating DWT lifting scheme that fits any size images by image renormalization has been proposed in this paper. This algorithm has a coding and decoding process without backtracking for dealing with the pixels of an image. It support LOCO-I and it can also be applied to Coder / Decoder. Simulation analysis indicates that the proposed method can achieve a high image compression. Compare with Lossless-JPG, PNG(Microsoft), PNG(Rene), PNG(Photoshop), PNG(Anix PicViewer), PNG(ACDSee), PNG(Ulead photo Explorer), JPEG2000, PNG(KoDa Inc), SPIHT and JPEG-LS, the lossless image compression ratio improved 45%, 29%, 25%, 21%, 19%, 17%, 16%, 15%, 11%, 10.5%, 10% separately with 24 pieces of RGB image provided by KoDa Inc. Accessing the main memory in Pentium IV,CPU2.20GHZ and 256MRAM, the coding speed of the proposed coder can be increased about 21 times than the SPIHT and the efficiency of the performance can be increased 166% or so, the decoder's coding speed can be increased about 17 times than the SPIHT and the efficiency of the performance can be increased 128% or so.

  19. Research on Copy-Move Image Forgery Detection Using Features of Discrete Polar Complex Exponential Transform

    Science.gov (United States)

    Gan, Yanfen; Zhong, Junliu

    2015-12-01

    With the aid of sophisticated photo-editing software, such as Photoshop, copy-move image forgery operation has been widely applied and has become a major concern in the field of information security in the modern society. A lot of work on detecting this kind of forgery has gained great achievements, but the detection results of geometrical transformations of copy-move regions are not so satisfactory. In this paper, a new method based on the Polar Complex Exponential Transform is proposed. This method addresses issues in image geometric moment, focusing on constructing rotation invariant moment and extracting features of the rotation invariant moment. In order to reduce rounding errors of the transform from the Polar coordinate system to the Cartesian coordinate system, a new transformation method is presented and discussed in detail at the same time. The new method constructs a 9 × 9 shrunk template to transform the Cartesian coordinate system back to the Polar coordinate system. It can reduce transform errors to a much greater degree. Forgery detection, such as copy-move image forgery detection, is a difficult procedure, but experiments prove our method is a great improvement in detecting and identifying forgery images affected by the rotated transform.

  20. Mixed-method research protocol: defining and operationalizing patient-related complexity of nursing care in acute care hospitals.

    Science.gov (United States)

    Huber, Evelyn; Kleinknecht-Dolf, Michael; Müller, Marianne; Kugler, Christiane; Spirig, Rebecca

    2017-06-01

    To define the concept of patient-related complexity of nursing care in acute care hospitals and to operationalize it in a questionnaire. The concept of patient-related complexity of nursing care in acute care hospitals has not been conclusively defined in the literature. The operationalization in a corresponding questionnaire is necessary, given the increased significance of the topic, due to shortened lengths of stay and increased patient morbidity. Hybrid model of concept development and embedded mixed-methods design. The theoretical phase of the hybrid model involved a literature review and the development of a working definition. In the fieldwork phase of 2015 and 2016, an embedded mixed-methods design was applied with complexity assessments of all patients at five Swiss hospitals using our newly operationalized questionnaire 'Complexity of Nursing Care' over 1 month. These data will be analysed with structural equation modelling. Twelve qualitative case studies will be embedded. They will be analysed using a structured process of constructing case studies and content analysis. In the final analytic phase, the quantitative and qualitative data will be merged and added to the results of the theoretical phase for a common interpretation. Cantonal Ethics Committee Zurich judged the research programme as unproblematic in December 2014 and May 2015. Following the phases of the hybrid model and using an embedded mixed-methods design can reach an in-depth understanding of patient-related complexity of nursing care in acute care hospitals, a final version of the questionnaire and an acknowledged definition of the concept. © 2016 John Wiley & Sons Ltd.

  1. Development of Complexity Science and Technology Tools for NextGen Airspace Research and Applications

    Science.gov (United States)

    Holmes, Bruce J.; Sawhill, Bruce K.; Herriot, James; Seehart, Ken; Zellweger, Dres; Shay, Rick

    2012-01-01

    The objective of this research by NextGen AeroSciences, LLC is twofold: 1) to deliver an initial "toolbox" of algorithms, agent-based structures, and method descriptions for introducing trajectory agency as a methodology for simulating and analyzing airspace states, including bulk properties of large numbers of heterogeneous 4D aircraft trajectories in a test airspace -- while maintaining or increasing system safety; and 2) to use these tools in a test airspace to identify possible phase transition structure to predict when an airspace will approach the limits of its capacity. These 4D trajectories continuously replan their paths in the presence of noise and uncertainty while optimizing performance measures and performing conflict detection and resolution. In this approach, trajectories are represented as extended objects endowed with pseudopotential, maintaining time and fuel-efficient paths by bending just enough to accommodate separation while remaining inside of performance envelopes. This trajectory-centric approach differs from previous aircraft-centric distributed approaches to deconfliction. The results of this project are the following: 1) we delivered a toolbox of algorithms, agent-based structures and method descriptions as pseudocode; and 2) we corroborated the existence of phase transition structure in simulation with the addition of "early warning" detected prior to "full" airspace. This research suggests that airspace "fullness" can be anticipated and remedied before the airspace becomes unsafe.

  2. Elements for Critical and Complex Research of Public Opinion in Chile

    Directory of Open Access Journals (Sweden)

    Emilio Andrés Venegas Vergara

    2015-08-01

    Full Text Available In this paper we discuss and propose theoretical elements considered relevant to open and develop a theoretical-empiric line of research on the public opinion (PO in Chile today. We suggest that there are different conceptions, practices and actors involved in “making PO”, recognizing five areas in this field: media system, subaltern counter-publics, social digital networks, survey industry and elites. In each of these areas it is necessary to inquire into their specific actors, practices and senses mobilized in the process of production of PO.The paper focuses on discussing the development of the main current comprehensive modalities of the PO and presenting a conceptual proposal for each of the five areas described above, as well as a brief characterization of these areas in Chile. We consider these definitions as a basic starting point to habilitate a line of research that allows us to design a device for monitoring PO. The device will be hosted at the PO observatory and it will contribute to activate networks of knowledge and action in the public sphere by providing periodically with public information regarding issues of general interest to the actors involved in the production of PO.

  3. International Conference on Translational Research ICTR 2003 Conference Summary: Marshalling resources in a complex time

    International Nuclear Information System (INIS)

    Coleman, C. Norman

    2004-01-01

    The knowledge, tools, and environment for the practice of radiation oncology are changing rapidly. The National Cancer Institute has articulated the need for a balanced portfolio, including the interrelated components of discovery, development, and delivery. Underpinning practice is the emerging knowledge from molecular, cellular, and tumor biology that is the engine of discovery. The use of high-throughput technologies to analyze biochemical and molecular profiles will ultimately enable the individualization of cancer treatment requiring the appropriate integration of radiation with a range of systemic therapies, including chemotherapy, biologic therapy, and immunotherapy. Technological advances in treatment delivery using photons, brachytherapy, particle therapy, radioisotopes, and other forms of energy require an improved ability to localize the tumor and critical subregions and to ensure necessary tissue immobilization and/or real-time target adjustment. Functional imaging is helping to define tumor characteristics and response to treatment. The development of appropriate radiation oncology treatment requires a wide range of expertise, a multimodality approach, and multi-institutional collaboration to provide improved and cost-effective outcome. The delivery of appropriate cancer care to those who need it requires biology and technology but also reaching the underserved populations worldwide. ICTR 2003 demonstrated substantial progress in translational radiation oncology. Faced with financial constraints for research and patient care, the broad field of radiation oncology must continually examine and balance its research and development portfolio and invest in its future leaders to enable it be an important contributor to the future of cancer care

  4. A comparison of pet and purpose-bred research dog (Canis familiaris) performance on human-guided object-choice tasks.

    Science.gov (United States)

    Lazarowski, Lucia; Dorman, David C

    2015-01-01

    Several studies have shown that domestic dogs respond to human social cues such as pointing. Some experiments have shown that pet dogs outperformed wolves in following a momentary distal point. These findings have lent support to the hypothesis that domestication is responsible for domestic dogs' ability to utilize human gestures. Other studies demonstrating comparable performance in human-socialized wolves suggest this skill depends on experience with relevant human stimuli. However, domestic dogs lacking thorough exposure to humans are underrepresented in the comparative literature. The goal of this study was to evaluate pet and kennel-reared research domestic dogs on their ability to follow two types of point in an object-choice task. This study used young adult, intact male research dogs (n=11) and a comparison group of pet dogs living in human homes (n=9). We found that while pet dogs followed the momentary distal point above chance levels, research dogs did not. Both groups followed the simpler dynamic proximal point; however, pet dogs outperformed research dogs on this task. Our results indicate that ontogenetic experiences may influence a domestic dog's ability to use human gestures, highlighting the importance of testing different sub-populations of domestic dogs. Copyright © 2014 Elsevier B.V. All rights reserved.

  5. Fort Collins Science Center Ecosystem Dynamics branch--interdisciplinary research for addressing complex natural resource issues across landscapes and time

    Science.gov (United States)

    Bowen, Zachary H.; Melcher, Cynthia P.; Wilson, Juliette T.

    2013-01-01

    The Ecosystem Dynamics Branch of the Fort Collins Science Center offers an interdisciplinary team of talented and creative scientists with expertise in biology, botany, ecology, geology, biogeochemistry, physical sciences, geographic information systems, and remote-sensing, for tackling complex questions about natural resources. As demand for natural resources increases, the issues facing natural resource managers, planners, policy makers, industry, and private landowners are increasing in spatial and temporal scope, often involving entire regions, multiple jurisdictions, and long timeframes. Needs for addressing these issues include (1) a better understanding of biotic and abiotic ecosystem components and their complex interactions; (2) the ability to easily monitor, assess, and visualize the spatially complex movements of animals, plants, water, and elements across highly variable landscapes; and (3) the techniques for accurately predicting both immediate and long-term responses of system components to natural and human-caused change. The overall objectives of our research are to provide the knowledge, tools, and techniques needed by the U.S. Department of the Interior, state agencies, and other stakeholders in their endeavors to meet the demand for natural resources while conserving biodiversity and ecosystem services. Ecosystem Dynamics scientists use field and laboratory research, data assimilation, and ecological modeling to understand ecosystem patterns, trends, and mechanistic processes. This information is used to predict the outcomes of changes imposed on species, habitats, landscapes, and climate across spatiotemporal scales. The products we develop include conceptual models to illustrate system structure and processes; regional baseline and integrated assessments; predictive spatial and mathematical models; literature syntheses; and frameworks or protocols for improved ecosystem monitoring, adaptive management, and program evaluation. The descriptions

  6. Towards a complex systems approach in sports injury research: simulating running-related injury development with agent-based modelling.

    Science.gov (United States)

    Hulme, Adam; Thompson, Jason; Nielsen, Rasmus Oestergaard; Read, Gemma J M; Salmon, Paul M

    2018-06-18

    There have been recent calls for the application of the complex systems approach in sports injury research. However, beyond theoretical description and static models of complexity, little progress has been made towards formalising this approach in way that is practical to sports injury scientists and clinicians. Therefore, our objective was to use a computational modelling method and develop a dynamic simulation in sports injury research. Agent-based modelling (ABM) was used to model the occurrence of sports injury in a synthetic athlete population. The ABM was developed based on sports injury causal frameworks and was applied in the context of distance running-related injury (RRI). Using the acute:chronic workload ratio (ACWR), we simulated the dynamic relationship between changes in weekly running distance and RRI through the manipulation of various 'athlete management tools'. The findings confirmed that building weekly running distances over time, even within the reported ACWR 'sweet spot', will eventually result in RRI as athletes reach and surpass their individual physical workload limits. Introducing training-related error into the simulation and the modelling of a 'hard ceiling' dynamic resulted in a higher RRI incidence proportion across the population at higher absolute workloads. The presented simulation offers a practical starting point to further apply more sophisticated computational models that can account for the complex nature of sports injury aetiology. Alongside traditional forms of scientific inquiry, the use of ABM and other simulation-based techniques could be considered as a complementary and alternative methodological approach in sports injury research. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  7. A Research Program on Implementing Integrated Care for Older Adults with Complex Health Needs (iCOACH: An International Collaboration

    Directory of Open Access Journals (Sweden)

    Walter P. Wodchis

    2018-05-01

    Full Text Available Health and social care systems across western developed nations are being challenged to meet the needs of an increasing number of people aging with multiple complex health and social needs. Community based primary health care (CBPHC has been associated with more equitable access to services, better population level outcomes and lower system level costs. Itmay be well suited to the increasingly complex needs of populations; however the implementation of CBPHC models of care faces many challenges. This paper describes a program of research by an international, multi-university, multidisciplinary research team who are seeking to understand how to scale up and spread models of Integrated CBPHC (ICBPHC. The key question being addressed is “What are the steps to implementing innovative integrated community-based primary health care models that address the health and social needs of older adults with complex care needs?” and will be answered in three phases. In the first phase we identify and describe exemplar models of ICBPHC and their context in relation to relevant policies and performance across the three jurisdictions (New Zealand, Ontario and Québec, Canada. The second phase involves a series of theory-informed, mixed methods case studies from which we shall develop a conceptual framework that captures not only the attributes of successful innovative ICBPHC models, but also how these models are being implemented. In the third phase, we aim to translate our research into practice by identifying emerging models of ICBPHC in advance, and working alongside policymakers to inform the development and implementation of these models in each jurisdiction. The final output of the program will be a comprehensive guide to the design, implementation and scaling-up of innovative models of ICBPHC.

  8. Communicative Purpose as Genre Determinant

    DEFF Research Database (Denmark)

    Askehave, Inger

    1999-01-01

    Through the years researchers and LSP teachers alike have used various parameters for classifying texts. This article sets out to discuss the notion of "communicative purpose" as a means for classifying text. It points to some of the difficulties associated with the functional approaches to genre...... classification in general and the notion of "communicative purpose" in particular.......Through the years researchers and LSP teachers alike have used various parameters for classifying texts. This article sets out to discuss the notion of "communicative purpose" as a means for classifying text. It points to some of the difficulties associated with the functional approaches to genre...

  9. I-RREACH: an engagement and assessment tool for improving implementation readiness of researchers, organizations and communities in complex interventions.

    Science.gov (United States)

    Maar, Marion; Yeates, Karen; Barron, Marcia; Hua, Diane; Liu, Peter; Moy Lum-Kwong, Margaret; Perkins, Nancy; Sleeth, Jessica; Tobe, Joshua; Wabano, Mary Jo; Williamson, Pamela; Tobe, Sheldon W

    2015-05-04

    Non-communicable chronic diseases are the leading causes of mortality globally, and nearly 80% of these deaths occur in low- and middle-income countries (LMICs). In high-income countries (HICs), inequitable distribution of resources affects poorer and otherwise disadvantaged groups including Aboriginal peoples. Cardiovascular mortality in high-income countries has recently begun to fall; however, these improvements are not realized among citizens in LMICs or those subgroups in high-income countries who are disadvantaged in the social determinants of health including Aboriginal people. It is critical to develop multi-faceted, affordable and realistic health interventions in collaboration with groups who experience health inequalities. Based on community-based participatory research (CBPR), we aimed to develop implementation tools to guide complex interventions to ensure that health gains can be realized in low-resource environments. We developed the I-RREACH (Intervention and Research Readiness Engagement and Assessment of Community Health Care) tool to guide implementation of interventions in low-resource environments. We employed CBPR and a consensus methodology to (1) develop the theoretical basis of the tool and (2) to identify key implementation factor domains; then, we (3) collected participant evaluation data to validate the tool during implementation. The I-RREACH tool was successfully developed using a community-based consensus method and is rooted in participatory principles, equalizing the importance of the knowledge and perspectives of researchers and community stakeholders while encouraging respectful dialogue. The I-RREACH tool consists of three phases: fact finding, stakeholder dialogue and community member/patient dialogue. The evaluation for our first implementation of I-RREACH by participants was overwhelmingly positive, with 95% or more of participants indicating comfort with and support for the process and the dialogue it creates. The I

  10. Endometriosis research: animal models for the study of a complex disease.

    Science.gov (United States)

    Tirado-González, Irene; Barrientos, Gabriela; Tariverdian, Nadja; Arck, Petra C; García, Mariana G; Klapp, Burghard F; Blois, Sandra M

    2010-11-01

    Endometriosis is a common gynaecological disease that is characterized and defined as the presence of endometrial tissue outside the uterus, causing painful periods and subfertility in approximately 10% of women. After more than 50 years of research, little is known about the mechanisms underlying the development and establishment of this condition. Animal models allow us to study the temporal sequence of events involved in disease establishment and progression. Also, because this disease occurs spontaneously only in humans and non-human primates and there are practical problems associated with studying the disease, animal models have been developed for the evaluation of endometriosis. This review describes the animal models for endometriosis that have been used to date, highlighting their importance for the investigation of disease mechanisms that would otherwise be more difficult to elucidate, and proposing new alternatives aimed at overcoming some of these limitations. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

  11. Research on Control Strategy of Complex Systems through VSC-HVDC Grid Parallel Device

    Directory of Open Access Journals (Sweden)

    Xue Mei-Juan

    2014-07-01

    Full Text Available After the completion of grid parallel, the device can turn to be UPFC, STATCOM, SSSC, research on the conversion circuit and transform method by corresponding switching operation. Accomplish the grid parallel and comprehensive control of the tie-line and stable operation and control functions of grid after parallel. Defines the function select operation switch matrix and grid parallel system branch variable, forming a switch matrix to achieve corresponding function of the composite system. Formed a criterion of the selection means to choose control strategy according to the switch matrix, to accomplish corresponding function. Put the grid parallel, STATCOM, SSSC and UPFC together as a system, improve the stable operation and flexible control of the power system.

  12. Research on the Topological Properties of Air Quality Index Based on a Complex Network

    Directory of Open Access Journals (Sweden)

    Yongli Zhang

    2018-04-01

    Full Text Available To analyze the dynamic characteristics of air quality for enforcing effective measures to prevent and evade air pollution harm, air quality index (AQI time series data was selected and transformed into a symbol sequence consisting of characters (H, M, L through the coarse graining process; then each 6-symbols series was treated as one vertex by time sequence to construct the AQI directed-weighted network; finally the centrality, clusterability, and ranking of the AQI network were analyzed. The results indicated that vertex strength and cumulative strength distribution, vertex strength and strength rank presented power law distributions, and the AQI network is a scale-free network. Only 17 vertices possessed a higher weighted clustering coefficient; meanwhile weighted clustering coefficient and vertex strength didn’t show a strong correlation. The AQI network did not have an obvious central tendency towards intermediaries in general, but 20.55% of vertices accounted for nearly 1/2 of the intermediaries, and the varieties still existed. The mean distance of 68.4932% of vertices was 6.120–9.973, the AQI network did not have obvious small-world phenomena, the conversion of AQI patterns presented the characteristics of periodicity and regularity, and 20.2055% of vertices had high proximity prestige. The vertices fell into six islands, the AQI pattern indicating heavy or serious air pollution lasting six days always lingered for a long time. The number of triads 2-012 was the largest, and the AQI network followed the transitivity model. The study has instructional significance in understanding time change regulation of air quality in Beijing, opening a new way for time series prediction research. Additionally, the factors causing the change of topological properties should be analyzed in the future research.

  13. Radiation synthesis of stimuli-responsive membranes, hydrogels and adsorbents for separation purposes. Final report of a coordinated research project 2000-2004

    International Nuclear Information System (INIS)

    2005-08-01

    This coordinated research project coordinated research work for the development of novel materials prepared by radiation processing techniques. Single and multi-pore polyamide membranes, fast thermo-responsive hydrogels, porous polymer monoliths, stimuli-responsive hydrogels based on natural and synthetic polymers, temperature responsive membranes, selective adsorbents, polymeric nanogels and novel non-ionic thermo-sensitive hydrogels were produced. The application areas explored for beneficially utilizing these novel materials included specialized drug delivery systems (DDS), selective adsorbents, nanopores for single molecule detection, membranes for separation and concentration of solutes, health care and remediation of environmental pollution. The report provides basic information on radiation processing and promotes experience exchange for further developments of radiation technology. Protocols and procedures of preparation of various stimuli responsive membranes and their actual and perspective applications are described in the report. Public awareness and technology acceptance are other factors to be considered for further dissemination. This publication summarizes the present status and the prospects of this technology

  14. Using the open Web as an information resource and scholarly Web search engines as retrieval tools for academic and research purposes

    OpenAIRE

    Filistea Naude; Chris Rensleigh; Adeline S.A. du Toit

    2010-01-01

    This study provided insight into the significance of the open Web as an information resource and Web search engines as research tools amongst academics. The academic staff establishment of the University of South Africa (Unisa) was invited to participate in a questionnaire survey and included 1188 staff members from five colleges. This study culminated in a PhD dissertation in 2008. One hundred and eighty seven respondents participated in the survey which gave a response rate of 15.7%. The re...

  15. Using the open Web as an information resource and scholarly Web search engines as retrieval tools for academic and research purposes

    Directory of Open Access Journals (Sweden)

    Filistea Naude

    2010-08-01

    Full Text Available This study provided insight into the significance of the open Web as an information resource and Web search engines as research tools amongst academics. The academic staff establishment of the University of South Africa (Unisa was invited to participate in a questionnaire survey and included 1188 staff members from five colleges. This study culminated in a PhD dissertation in 2008. One hundred and eighty seven respondents participated in the survey which gave a response rate of 15.7%. The results of this study show that academics have indeed accepted the open Web as a useful information resource and Web search engines as retrieval tools when seeking information for academic and research work. The majority of respondents used the open Web and Web search engines on a daily or weekly basis to source academic and research information. The main obstacles presented by using the open Web and Web search engines included lack of time to search and browse the Web, information overload, poor network speed and the slow downloading speed of webpages.

  16. Using the open Web as an information resource and scholarly Web search engines as retrieval tools for academic and research purposes

    Directory of Open Access Journals (Sweden)

    Filistea Naude

    2010-12-01

    Full Text Available This study provided insight into the significance of the open Web as an information resource and Web search engines as research tools amongst academics. The academic staff establishment of the University of South Africa (Unisa was invited to participate in a questionnaire survey and included 1188 staff members from five colleges. This study culminated in a PhD dissertation in 2008. One hundred and eighty seven respondents participated in the survey which gave a response rate of 15.7%. The results of this study show that academics have indeed accepted the open Web as a useful information resource and Web search engines as retrieval tools when seeking information for academic and research work. The majority of respondents used the open Web and Web search engines on a daily or weekly basis to source academic and research information. The main obstacles presented by using the open Web and Web search engines included lack of time to search and browse the Web, information overload, poor network speed and the slow downloading speed of webpages.

  17. Research on Statistical Flow of the Complex Background Based on Image Method

    Directory of Open Access Journals (Sweden)

    Yang Huanhai

    2014-06-01

    Full Text Available Along with our country city changes a process continues to accelerate, city road traffic system pressure increasing. Therefore, the importance of intelligent transportation system based on computer vision technology is becoming more and more significant. Using the image processing technology for the vehicle detection has become a hot topic in the research field of. Only accurately segmented from the background of vehicle can recognize and track vehicles. Therefore, the application of video vehicle detection technology and image processing technology, identify a number of the same sight many car can, types and moving characteristics, can provide real-time basis for intelligent traffic control. This paper first introduces the concept of intelligent transportation system, the importance and the image processing technology in vehicle recognition in statistics, overview of video vehicle detection method, and the video detection technology and other detection technology, puts forward the superiority of video detection technology. Finally we design a real-time and reliable background subtraction method and the area of the vehicle recognition method based on information fusion algorithm, which is implemented with the MATLAB/GUI development tool in Windows operating system platform. In this paper, the application of the algorithm to study the frame traffic flow image. The experimental results show that, the algorithm of recognition of vehicle flow statistics, the effect is very good.

  18. Serotonin's Complex Role in Alcoholism: Implications for Treatment and Future Research.

    Science.gov (United States)

    Marcinkiewcz, Catherine A; Lowery-Gionta, Emily G; Kash, Thomas L

    2016-06-01

    Current pharmacological treatments for alcohol dependence have focused on reducing alcohol consumption, but to date there are few treatments that also address the negative affective symptoms during acute and protracted alcohol withdrawal which are often exacerbated in people with comorbid anxiety and depression. Selective serotonin reuptake inhibitors (SSRIs) are sometimes prescribed to ameliorate these symptoms but can exacerbate anxiety and cravings in a select group of patients. In this critical review, we discuss recent literature describing an association between alcohol dependence, the SERT linked polymorphic region (5-HTTLPR), and pharmacological response to SSRIs. Given the heterogeneity in responsiveness to serotonergic drugs across the spectrum of alcoholic subtypes, we assess the contribution of specific 5-HT circuits to discrete endophenotypes of alcohol dependence. 5-HT circuits play a distinctive role in reward, stress, and executive function which may account for the variation in response to serotonergic drugs. New optogenetic and chemogenetic methods for dissecting 5-HT circuits in alcohol dependence may provide clues leading to more effective pharmacotherapies. Although our current understanding of the role of 5-HT systems in alcohol dependence is incomplete, there is some evidence to suggest that 5-HT3 receptor antagonists are effective in people with the L/L genotype of the 5-HTTLPR polymorphism while SSRIs may be more beneficial to people with the S/L or S/S genotype. Studies that assess the impact of serotonin transporter polymorphisms on 5-HT circuit function and the subsequent development of alcohol use disorders will be an important step forward in treating alcohol dependence. Copyright © 2016 by the Research Society on Alcoholism.

  19. Radiation exposure of the personnel during dismantling and cutting of the primary system of the Karlsruhe Multi-purpose Research Reactor (MZFR)

    International Nuclear Information System (INIS)

    Hesse, H.; Demant, W.; Reichert, A.; Willmann, F.

    2000-10-01

    The heavy water (D 2 O) cooled and moderated pressurized water reactor MZFR with a thermal power of 200 MW will be dismantled step-by-step within the framework of sectional decommissioning licenses. The past decommissioning step (6 th sectional license) in general covered the removal of the primary systems and of all reactor support systems inside the reactor building. The measures for radiation protection during dismantling and handling of the large components of the primary system, such as the fuel element loading machine, fuel element transfer system, steam generator and pressurizer shall be pointed out. The measures taken for the reduction of the dose rate during dismantling and cutting of the components for the purpose of conditioning or unrestricted reuse at the central decontamination department (HDB) shall be described. Chemical decontamination of the primary circuit and its components, which had to be executed in order to reduce the dose rates for subsequent manual dismantling, shall be presented. The efforts undertaken for the protection of individuals in view of the difficult radiological boundary conditions (high concentrations of tritium in all systems as well as very high alpha contamination) will be explained. Moreover, dose-minimizing measures during cutting of the primary circuit and its components at HDB shall be described by the example of the cutting of a steam generator. It shall be demonstrated that cutting and dismantling of highly contaminated and activated parts with high dose rates can be executed safely in terms of both the radiation exposure of the personnel and the technical, financial and time expenditure. (orig.)

  20. Amostragem domiciliar contínua em estudos epidemiológicos e no ensino Continuous household sampling for epidemiological research and for teaching purposes

    Directory of Open Access Journals (Sweden)

    José da Rocha Carvalheiro

    1979-09-01

    Full Text Available Descreve-se um sistema contínuo de levantamento de condições de saúde, por entrevistas domiciliárias, operando em Ribeirão Preto (SP desde 1974. Comentam-se as vantagens quanto à sua utilização na investigação de problemas específicos surgidos nesse período, bem como a sua utilização no ensino.The use of adequate populational-base survey is frequently impossible in epidemiological studies. Special studies are made among particular groups of individuals to investigate simultaneously the presence of both the factor and the disease. In these studies it is obviously important to use adequate sampling techniques. A system of continuous household sampling is described, designed to perform, simultaneously, epidemiological research, health system monitoring and to serve as a basis for courses on sampling techniques and epidemiological methods. In the municipality of Ribeirão Preto, S. Paulo, Brazil a household sampling system has been in operation since 1974, using a master sample of 8500 households. Every two weeks, 380 households are visited and information is gathered about diseases, accidents, and the use of health services. Special epidemiological research is introduced when necessary. Future development includes the use of standardized questionnaires and physical and laboratory examinations of the people interviewed.

  1. Helios: a Multi-Purpose LIDAR Simulation Framework for Research, Planning and Training of Laser Scanning Operations with Airborne, Ground-Based Mobile and Stationary Platforms

    Science.gov (United States)

    Bechtold, S.; Höfle, B.

    2016-06-01

    In many technical domains of modern society, there is a growing demand for fast, precise and automatic acquisition of digital 3D models of a wide variety of physical objects and environments. Laser scanning is a popular and widely used technology to cover this demand, but it is also expensive and complex to use to its full potential. However, there might exist scenarios where the operation of a real laser scanner could be replaced by a computer simulation, in order to save time and costs. This includes scenarios like teaching and training of laser scanning, development of new scanner hardware and scanning methods, or generation of artificial scan data sets to support the development of point cloud processing and analysis algorithms. To test the feasibility of this idea, we have developed a highly flexible laser scanning simulation framework named Heidelberg LiDAR Operations Simulator (HELIOS). HELIOS is implemented as a Java library and split up into a core component and multiple extension modules. Extensible Markup Language (XML) is used to define scanner, platform and scene models and to configure the behaviour of modules. Modules were developed and implemented for (1) loading of simulation assets and configuration (i.e. 3D scene models, scanner definitions, survey descriptions etc.), (2) playback of XML survey descriptions, (3) TLS survey planning (i.e. automatic computation of recommended scanning positions) and (4) interactive real-time 3D visualization of simulated surveys. As a proof of concept, we show the results of two experiments: First, a survey planning test in a scene that was specifically created to evaluate the quality of the survey planning algorithm. Second, a simulated TLS scan of a crop field in a precision farming scenario. The results show that HELIOS fulfills its design goals.

  2. The complex nature of mixed farming systems requires multidimensional actions supported by integrative research and development efforts.

    Science.gov (United States)

    González-García, E; Gourdine, J L; Alexandre, G; Archimède, H; Vaarst, M

    2012-05-01

    Mixed farming systems (MFS) have demonstrated some success by focusing on the use of integrative and holistic mechanisms, and rationally building on and using the natural and local resource base without exhausting it, while enhancing biodiversity, optimizing complementarities between crops and animal systems and finally increasing opportunities in rural livelihoods. Focusing our analysis and discussion on field experiences and empirical knowledge in the Caribbean islands, this paper discusses the opportunities for a change needed in current MFS research-development philosophy. The importance of shifting from fragile/specialized production systems to MFS under current global conditions is argued with an emphasis on the case of Small Islands Developing States (SIDS) and the Caribbean. Particular vulnerable characteristics as well as the potential and constraints of SIDS and their agricultural sectors are described, while revealing the opportunities for the 'richness' of the natural and local resources to support authentic and less dependent production system strategies. Examples are provided of the use of natural grasses, legumes, crop residues and agro-industrial by-products. We analyse the requirement for a change in research strategies and initiatives through the development of a complex but necessary multi-/inter-/trans-disciplinary teamwork spirit. We stress as essential the collaboration and active participation of local and regional actors, stakeholders and end-users in the identification of research priorities, as well as the generation, exchange and dissemination of knowledge and technology innovations, while strengthening the leadership roles in the conduct of integrative and participative research and development projects.

  3. Resolving complex research data management issues in biomedical laboratories: Qualitative study of an industry-academia collaboration.

    Science.gov (United States)

    Myneni, Sahiti; Patel, Vimla L; Bova, G Steven; Wang, Jian; Ackerman, Christopher F; Berlinicke, Cynthia A; Chen, Steve H; Lindvall, Mikael; Zack, Donald J

    2016-04-01

    This paper describes a distributed collaborative effort between industry and academia to systematize data management in an academic biomedical laboratory. Heterogeneous and voluminous nature of research data created in biomedical laboratories make information management difficult and research unproductive. One such collaborative effort was evaluated over a period of four years using data collection methods including ethnographic observations, semi-structured interviews, web-based surveys, progress reports, conference call summaries, and face-to-face group discussions. Data were analyzed using qualitative methods of data analysis to (1) characterize specific problems faced by biomedical researchers with traditional information management practices, (2) identify intervention areas to introduce a new research information management system called Labmatrix, and finally to (3) evaluate and delineate important general collaboration (intervention) characteristics that can optimize outcomes of an implementation process in biomedical laboratories. Results emphasize the importance of end user perseverance, human-centric interoperability evaluation, and demonstration of return on investment of effort and time of laboratory members and industry personnel for success of implementation process. In addition, there is an intrinsic learning component associated with the implementation process of an information management system. Technology transfer experience in a complex environment such as the biomedical laboratory can be eased with use of information systems that support human and cognitive interoperability. Such informatics features can also contribute to successful collaboration and hopefully to scientific productivity. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  4. Redevelopment of the Arctic Area of Russia as an Objective of Systems Research and Special-Purpose Program Management Methodological Issues

    Directory of Open Access Journals (Sweden)

    Vladimir Nikolayevich Leksin

    2015-12-01

    Full Text Available The paper substantiates the methodological foundations of implementation of the rules and regulations of the development of the Arctic region of Russia, which relies on the hypothesis interpreting such development as the biggest integrated megaproject in the history of Russia. The substantiation involves both the project-oriented approach to identify the subject-matter of the research and the systems approach to assess the key opportunities of providing the integrative structure of the megaproject in the conditions of drastic differences between the areal components of the Arctic region, and to study the internal and external factors’ impact on the character, drivers and pace of the region redevelopment. The set of consistent methodological positions concerning their policy implementation by responsible governmental agencies in the foreseeable future of the Arctic is developed. The most important position involves the identification of the objective of the public administration of the Arctic region development as a systemically organized entity of multiple coordinated actions of the federal, regional and municipal authorities, corporations and civil society institutions integrated by the unique policy target and economic, social and infrastructure links. Implementation of the public administration requires the principles of systems approach, the reasonable trade-off between centralization, decentralization and continuity of governance focused exclusively on the Arctic issues. At the same time, the integration of the projects of the region’s areal components development to insure the common targets of the Arctic’s megaproject accompanied by the reconsideration of the earlier developed programs turns into a genuinely new methodological issue. In the article, recommendations to provide such integration are introduced.

  5. Illustrating idiographic methods for translation research: moderation effects, natural clinical experiments, and complex treatment-by-subgroup interactions.

    Science.gov (United States)

    Ridenour, Ty A; Wittenborn, Andrea K; Raiff, Bethany R; Benedict, Neal; Kane-Gill, Sandra

    2016-03-01

    A critical juncture in translation research involves the preliminary studies of intervention tools, provider training programs, policies, and other mechanisms used to leverage knowledge garnered at one translation stage into another stage. Potentially useful for such studies are rigorous techniques for conducting within-subject clinical trials, which have advanced incrementally over the last decade. However, these methods have largely not been utilized within prevention or translation contexts. The purpose of this manuscript is to demonstrate the flexibility, wide applicability, and rigor of idiographic clinical trials for preliminary testing of intervention mechanisms. Specifically demonstrated are novel uses of state-space modeling for testing intervention mechanisms of short-term outcomes, identifying heterogeneity in and moderation of within-person treatment mechanisms, a horizontal line plot to refine sampling design during the course of a clinic-based experimental study, and the need to test a treatment's efficacy as treatment is administered along with (e.g., traditional 12-month outcomes).

  6. Is there a reasonable excuse for not providing post-operative analgesia when using animal models of peripheral neuropathic pain for research purposes?

    Directory of Open Access Journals (Sweden)

    Sara Hestehave

    Full Text Available The induction of neuropathic pain-like behaviors in rodents often requires surgical intervention. This engages acute nociceptive signaling events that contribute to pain and stress post-operatively that from a welfare perspective demands peri-operative analgesic treatment. However, a large number of researchers avoid providing such care based largely on anecdotal opinions that it might interfere with model pathophysiology in the longer term.To investigate effects of various peri-operative analgesic regimens encapsulating different mechanisms and duration of action, on the development of post-operative stress/welfare and pain-like behaviors in the Spared Nerve Injury (SNI-model of neuropathic pain.Starting on the day of surgery, male Sprague-Dawley rats were administered either vehicle (s.c., carprofen (5.0mg/kg, s.c., buprenorphine (0.1mg/kg s.c. or 1.0mg/kg p.o. in Nutella®, lidocaine/bupivacaine mixture (local irrigation or a combination of all analgesics, with coverage from a single administration, and up to 72 hours. Post-operative stress and recovery were assessed using welfare parameters, bodyweight, food-consumption, and fecal corticosterone, and hindpaw mechanical allodynia was tested for assessing development of neuropathic pain for 28 days.None of the analgesic regimes compromised the development of mechanical allodynia. Unexpectedly, the combined treatment with 0.1mg/kg s.c. buprenorphine and carprofen for 72 hours and local irrigation with lidocaine/bupivacaine, caused severe adverse effects with peritonitis. This was not observed when the combination included a lower dose of buprenorphine (0.05mg/kg, s.c., or when buprenorphine was administered alone (0.1mg/kg s.c. or 1.0mg/kg p.o. for 72 hours. An elevated rate of wound dehiscence was observed especially in the combined treatment groups, underlining the need for balanced analgesia. Repeated buprenorphine injections had positive effects on body weight the first day after surgery

  7. SemEHR: A general-purpose semantic search system to surface semantic data from clinical notes for tailored care, trial recruitment, and clinical research.

    Science.gov (United States)

    Wu, Honghan; Toti, Giulia; Morley, Katherine I; Ibrahim, Zina M; Folarin, Amos; Jackson, Richard; Kartoglu, Ismail; Agrawal, Asha; Stringer, Clive; Gale, Darren; Gorrell, Genevieve; Roberts, Angus; Broadbent, Matthew; Stewart, Robert; Dobson, Richard J B

    2018-05-01

    Unlocking the data contained within both structured and unstructured components of electronic health records (EHRs) has the potential to provide a step change in data available for secondary research use, generation of actionable medical insights, hospital management, and trial recruitment. To achieve this, we implemented SemEHR, an open source semantic search and analytics tool for EHRs. SemEHR implements a generic information extraction (IE) and retrieval infrastructure by identifying contextualized mentions of a wide range of biomedical concepts within EHRs. Natural language processing annotations are further assembled at the patient level and extended with EHR-specific knowledge to generate a timeline for each patient. The semantic data are serviced via ontology-based search and analytics interfaces. SemEHR has been deployed at a number of UK hospitals, including the Clinical Record Interactive Search, an anonymized replica of the EHR of the UK South London and Maudsley National Health Service Foundation Trust, one of Europe's largest providers of mental health services. In 2 Clinical Record Interactive Search-based studies, SemEHR achieved 93% (hepatitis C) and 99% (HIV) F-measure results in identifying true positive patients. At King's College Hospital in London, as part of the CogStack program (github.com/cogstack), SemEHR is being used to recruit patients into the UK Department of Health 100 000 Genomes Project (genomicsengland.co.uk). The validation study suggests that the tool can validate previously recruited cases and is very fast at searching phenotypes; time for recruitment criteria checking was reduced from days to minutes. Validated on open intensive care EHR data, Medical Information Mart for Intensive Care III, the vital signs extracted by SemEHR can achieve around 97% accuracy. Results from the multiple case studies demonstrate SemEHR's efficiency: weeks or months of work can be done within hours or minutes in some cases. SemEHR provides a more

  8. Combining Purpose With Profits

    DEFF Research Database (Denmark)

    Julian Birkinshaw, Julian; Foss, Nicolai Juul; Lindenberg, Siegwart

    2014-01-01

    A sense of purpose that transcends making money can motivate employees. But to sustain both a sense of purpose and a solid level of profitability over time, companies need to pay attention to several fundamental organizing principles....

  9. Taking peer victimization research to the next level: complex interactions among genes, teacher attitudes/behaviors, peer ecologies, & classroom characteristics.

    Science.gov (United States)

    Espelage, Dorothy L

    2015-01-01

    This commentary reviews research findings of the five papers in the special entitled "School-related Factors in the Development of Bullying Perpetration and Victimization", which represent critical areas that are often overlooked in the literature. First, one paper points to the complex interaction between a genetic disposition for aggression and classroom norms toward aggression. Second, an intervention paper unpacks the underlying mechanisms of an efficacious school-wide bully prevention program by opening the "black box" and testing for mediators. Third, the remaining studies employ a wide range of rigorous designs to identify how teachers' attitudes, behaviors, and classroom practices play a critical role in the prevalence of victimization and bullying in the classroom. Further, teachers' attitudes and behaviors are shown to be predictive of youth's willingness to intervene to assist a peer who is being victimized. Results are situated in what is known about bullying prevention, and how the findings from these studies could maximize the sensitivity of future prevention efforts.

  10. Dual-harmonic auto voltage control for the rapid cycling synchrotron of the Japan Proton Accelerator Research Complex

    Directory of Open Access Journals (Sweden)

    Fumihiko Tamura

    2008-07-01

    Full Text Available The dual-harmonic operation, in which the accelerating cavities are driven by the superposition of the fundamental and the second harmonic rf voltage, is useful for acceleration of the ultrahigh intensity proton beam in the rapid cycling synchrotron (RCS of Japan Proton Accelerator Research Complex (J-PARC. However, the precise and fast voltage control of the harmonics is necessary to realize the dual-harmonic acceleration. We developed the dual-harmonic auto voltage control system for the J-PARC RCS. We describe details of the design and the implementation. Various tests of the system are performed with the RCS rf system. Also, a preliminary beam test has been done. We report the test results.

  11. Materials and Life Science Experimental Facility (MLF at the Japan Proton Accelerator Research Complex II: Neutron Scattering Instruments

    Directory of Open Access Journals (Sweden)

    Kenji Nakajima

    2017-11-01

    Full Text Available The neutron instruments suite, installed at the spallation neutron source of the Materials and Life Science Experimental Facility (MLF at the Japan Proton Accelerator Research Complex (J-PARC, is reviewed. MLF has 23 neutron beam ports and 21 instruments are in operation for user programs or are under commissioning. A unique and challenging instrumental suite in MLF has been realized via combination of a high-performance neutron source, optimized for neutron scattering, and unique instruments using cutting-edge technologies. All instruments are/will serve in world-leading investigations in a broad range of fields, from fundamental physics to industrial applications. In this review, overviews, characteristic features, and typical applications of the individual instruments are mentioned.

  12. Beam commissioning of the 3-GeV rapid cycling synchrotron of the Japan Proton Accelerator Research Complex

    Directory of Open Access Journals (Sweden)

    H. Hotchi

    2009-04-01

    Full Text Available The 3-GeV rapid cycling synchrotron (RCS of the Japan Proton Accelerator Research Complex (J-PARC was commissioned in October 2007, and successfully accomplished 3 GeV acceleration on October 31. Six run cycles through February 2008 were dedicated to commissioning the RCS, for which the initial machine parameter tuning and various underlying beam studies were completed. Then since May 2008 the RCS beam has been delivered to the downstream facilities for their beam commissioning. In this paper we describe beam tuning and study results following our beam commissioning scenario and a beam performance and operational experience obtained in the first commissioning phase through June 2008.

  13. Overview of Japan Proton Accelerator Research Complex (J-PARC) project and Materials and Life Science Experimental Facility (MLF)

    International Nuclear Information System (INIS)

    Ikeda, Yujiro

    2008-01-01

    The J-PARC project has been conducted jointly by JAERI and KEK since 2001. This paper reports an overview and current status of the project. The high intensity proton accelerator consists of a 400 MeV Linac, a 3 GeV synchrotron and 50 GeV synchrotron to deliver MW level pulsed proton beam to experimental facilities. The MW proton power will provide an advanced scientific experimental research complex aiming at making breakthroughs in materials and life science with neutron and muon, nuclear and elementary physics, etc. Regarding the project being close to its completion in 2008, this paper describes the overview of J-PARC project with emphasis of the Materials and Life Science Experimental Facility, in which the MW pulsed neutron and muon sources, are placed to provide high quality neutron and muon beams to the world wide users. (author)

  14. [Complexity, law and science: Reflections on the UNESCO Recommendation on the status and responsibility of the scientific researcher].

    Science.gov (United States)

    Byk, Christian

    2017-10-13

    The analysis of the complexity and interactivity in the production of social norms between science and technology, on the one hand, and between law and ethics, on the other hand, must be our first concern because without a lucid and in deep assessment of the fragmented and even opposed realities that make up our world, not only do we lose all forms of collective freedom but above all we favor reductive totalitarianism and warlike confrontation.It is with this in mind that it is necessary to examine whether the revision of the 1974 Recommendation on the Status and Responsibility of the Scientific Researcher is likely to provide relevant elements for responding to these changes.

  15. Purpose and Professional Writers.

    Science.gov (United States)

    Blyler, Nancy Roundy

    1989-01-01

    Describes a protocol study of 10 professional writers which examined the meaning and influence of purpose on writers in the workplace. Explores the interactions of various purpose considerations derived from situation, reader, and text. Suggests that professional writers have a range of meanings in mind when they think about purpose. (MM)

  16. Educational Purpose Cardiopulmonary Resuscitation Simulator

    Directory of Open Access Journals (Sweden)

    DRAGHICIU Nicolae

    2014-05-01

    Full Text Available Along with the development of computers and other sciences we can use in our personal projects complex structures built with microcontrollers. They miniaturise and simplify the final project, instead they depend/rely on the computer, through the programming of the microcontroller/s/them. This project presents the application of electronics in order to achieve a resuscitation mannequin for didactic purpose, using Arduino Prototyping Platform.

  17. Researching Complex Heat, Air and Moisture Interactions for a Wide-Range of Building Envelope Systems and Environmental Loads

    Energy Technology Data Exchange (ETDEWEB)

    Karagiozis, A.N.

    2007-05-15

    This document serves as the final report documenting work completed by Oak Ridge National Laboratory (ORNL) and the Fraunhofer Institute in Building Physics (Holzkirchen, Germany) under an international CRADA No. 0575 with Fraunhofer Institute of Bauphysics of the Federal Republic of Germany for Researching Complex Heat, Air and Moisture Interactions for a Wide Range of Building Envelope Systems and Environmental Loads. This CRADA required a multi-faceted approach to building envelope research that included a moisture engineering approach by blending extensive material property analysis, laboratory system and sub-system thermal and moisture testing, and advanced moisture analysis prediction performance. The Participant's Institute for Building physics (IBP) and the Contractor's Buildings Technology Center (BTC) identified potential research projects and activities capable of accelerating and advancing the development of innovative, low energy and durable building envelope systems in diverse climates. This allowed a major leverage of the limited resources available to ORNL to execute the required Department of Energy (DOE) directives in the area of moisture engineering. A joint working group (ORNL and Fraunhofer IBP) was assembled and a research plan was executed from May 2000 to May 2005. A number of key deliverables were produced such as adoption of North American loading into the WUFI-software. in addition the ORNL Weather File Analyzer was created and this has been used to address environmental loading for a variety of US climates. At least 4 papers have been co-written with the CRADA partners, and a chapter in the ASTM Manual 40 on Moisture Analysis and Condensation Control. All deliverables and goals were met and exceeded making this collaboration a success to all parties involves.

  18. Safety Research and Experimental Coal Mines

    Data.gov (United States)

    Federal Laboratory Consortium — Safety Research and Experimental Coal MinesLocation: Pittsburgh SiteThe Safety Research Coal Mine and Experimental Mine complex is a multi-purpose underground mine...

  19. Resisting the seduction of "ethics creep": using Foucault to surface complexity and contradiction in research ethics review.

    Science.gov (United States)

    Guta, Adrian; Nixon, Stephanie A; Wilson, Michael G

    2013-12-01

    In this paper we examine "ethics creep", a concept developed by Haggerty (2004) to account for the increasing bureaucratization of research ethics boards and institutional review boards (REB/IRBs) and the expanding reach of ethics review. We start with an overview of the recent surge of academic interest in ethics creep and similar arguments about the prohibitive effect of ethics review. We then introduce elements of Michel Foucault's theoretical framework which are used to inform our analysis of empirical data drawn from a multi-phase study exploring the accessibility of community-engaged research within existing ethics review structures in Canada. First, we present how ethics creep emerged both explicitly and implicitly in our data. We then present data that demonstrate how REB/IRBs are experiencing their own form of regulation. Finally, we present data that situate ethics review alongside other trends affecting the academy. Our results show that ethics review is growing in some ways while simultaneously being constrained in others. Drawing on Foucauldian theory we reframe ethics creep as a repressive hypothesis which belies the complexity of the phenomenon it purports to explain. Our discussion complicates ethics creep by proposing an understanding of REB/IRBs that locates them at the intersection of various neoliberal discourses about the role of science, ethics, and knowledge production. Copyright © 2012 Elsevier Ltd. All rights reserved.

  20. Synthesizing models useful for ecohydrology and ecohydraulic approaches: An emphasis on integrating models to address complex research questions

    Science.gov (United States)

    Brewer, Shannon K.; Worthington, Thomas; Mollenhauer, Robert; Stewart, David; McManamay, Ryan; Guertault, Lucie; Moore, Desiree

    2018-01-01

    Ecohydrology combines empiricism, data analytics, and the integration of models to characterize linkages between ecological and hydrological processes. A challenge for practitioners is determining which models best generalizes heterogeneity in hydrological behaviour, including water fluxes across spatial and temporal scales, integrating environmental and socio‐economic activities to determine best watershed management practices and data requirements. We conducted a literature review and synthesis of hydrologic, hydraulic, water quality, and ecological models designed for solving interdisciplinary questions. We reviewed 1,275 papers and identified 178 models that have the capacity to answer an array of research questions about ecohydrology or ecohydraulics. Of these models, 43 were commonly applied due to their versatility, accessibility, user‐friendliness, and excellent user‐support. Forty‐one of 43 reviewed models were linked to at least 1 other model especially: Water Quality Analysis Simulation Program (linked to 21 other models), Soil and Water Assessment Tool (19), and Hydrologic Engineering Center's River Analysis System (15). However, model integration was still relatively infrequent. There was substantial variation in model applications, possibly an artefact of the regional focus of research questions, simplicity of use, quality of user‐support efforts, or a limited understanding of model applicability. Simply increasing the interoperability of model platforms, transformation of models to user‐friendly forms, increasing user‐support, defining the reliability and risk associated with model results, and increasing awareness of model applicability may promote increased use of models across subdisciplines. Nonetheless, the current availability of models allows an array of interdisciplinary questions to be addressed, and model choice relates to several factors including research objective, model complexity, ability to link to other models, and

  1. Is it acceptable to video-record palliative care consultations for research and training purposes? A qualitative interview study exploring the views of hospice patients, carers and clinical staff.

    Science.gov (United States)

    Pino, Marco; Parry, Ruth; Feathers, Luke; Faull, Christina

    2017-09-01

    Research using video recordings can advance understanding of healthcare communication and improve care, but making and using video recordings carries risks. To explore views of hospice patients, carers and clinical staff about whether videoing patient-doctor consultations is acceptable for research and training purposes. We used semi-structured group and individual interviews to gather hospice patients, carers and clinical staff views. We used Braun and Clark's thematic analysis. Interviews were conducted at one English hospice to inform the development of a larger video-based study. We invited patients with capacity to consent and whom the care team judged were neither acutely unwell nor severely distressed (11), carers of current or past patients (5), palliative medicine doctors (7), senior nurses (4) and communication skills educators (5). Participants viewed video-based research on communication as valuable because of its potential to improve communication, care and staff training. Video-based research raised concerns including its potential to affect the nature and content of the consultation and threats to confidentiality; however, these were not seen as sufficient grounds for rejecting video-based research. Video-based research was seen as acceptable and useful providing that measures are taken to reduce possible risks across the recruitment, recording and dissemination phases of the research process. Video-based research is an acceptable and worthwhile way of investigating communication in palliative medicine. Situated judgements should be made about when it is appropriate to involve individual patients and carers in video-based research on the basis of their level of vulnerability and ability to freely consent.

  2. The Special Purpose Vehicle

    DEFF Research Database (Denmark)

    Fomcenco, Alex

    2013-01-01

    The purpose of this article is to investigate whether the situation where two companies appear as originators or sponsors behind a Special Purpose Vehicle (SPV) can be described as a merger, although on micro scale. Are the underlying grounds behind the creation of an SPV much different than those...

  3. Why Antidiabetic Vanadium Complexes are Not in the Pipeline of "Big Pharma" Drug Research? A Critical Review.

    Science.gov (United States)

    Scior, Thomas; Guevara-Garcia, Jose Antonio; Do, Quoc-Tuan; Bernard, Philippe; Laufer, Stefan

    2016-01-01

    Public academic research sites, private institutions as well as small companies have made substantial contributions to the ongoing development of antidiabetic vanadium compounds. But why is this endeavor not echoed by the globally operating pharmaceutical companies, also known as "Big Pharma"? Intriguingly, today's clinical practice is in great need to improve or replace insulin treatment against Diabetes Mellitus (DM). Insulin is the mainstay therapeutically and economically. So, why do those companies develop potential antidiabetic drug candidates without vanadium (vanadium- free)? We gathered information about physicochemical and pharmacological properties of known vanadium-containing antidiabetic compounds from the specialized literature, and converted the data into explanations (arguments, the "pros and cons") about the underpinnings of antidiabetic vanadium. Some discoveries were embedded in chronological order while seminal reviews of the last decade about the Medicinal chemistry of vanadium and its history were also listed for further understanding. In particular, the concepts of so-called "noncomplexed or free" vanadium species (i.e. inorganic oxido-coordinated species) and "biogenic speciation" of antidiabetic vanadium complexes were found critical and subsequently documented in more details to answer the question.

  4. Developing a Mathematical Model for Scheduling and Determining Success Probability of Research Projects Considering Complex-Fuzzy Networks

    Directory of Open Access Journals (Sweden)

    Gholamreza Norouzi

    2015-01-01

    Full Text Available In project management context, time management is one of the most important factors affecting project success. This paper proposes a new method to solve research project scheduling problems (RPSP containing Fuzzy Graphical Evaluation and Review Technique (FGERT networks. Through the deliverables of this method, a proper estimation of project completion time (PCT and success probability can be achieved. So algorithms were developed to cover all features of the problem based on three main parameters “duration, occurrence probability, and success probability.” These developed algorithms were known as PR-FGERT (Parallel and Reversible-Fuzzy GERT networks. The main provided framework includes simplifying the network of project and taking regular steps to determine PCT and success probability. Simplifications include (1 equivalent making of parallel and series branches in fuzzy network considering the concepts of probabilistic nodes, (2 equivalent making of delay or reversible-to-itself branches and impact of changing the parameters of time and probability based on removing related branches, (3 equivalent making of simple and complex loops, and (4 an algorithm that was provided to resolve no-loop fuzzy network, after equivalent making. Finally, the performance of models was compared with existing methods. The results showed proper and real performance of models in comparison with existing methods.

  5. The Process of Handling an Excess of Complex and Interdisciplinary Information in a Decision Support Research Situation

    Directory of Open Access Journals (Sweden)

    Fredrik Moltu Johnsen

    2017-06-01

    Full Text Available Researchers are sometimes expected to investigate a complex and interdisciplinary subject-matter in order to provide scientific support for large-scale decisions. This may prove challenging: typically, a lack of cohesion between the pieces of information investigated in the starting phase may cause confusion. This article suggests one possible road from this problem, which may lead to holistic understanding and next to communication and implementation of this understanding. The process is presented as a diagram, and selected aspects of it are analysed. The process involves moving to a higher level of generalisation in order to gain a better overview and potentially invent new concepts, and next moving back to a more detailed level in order to communicate and implement these insights. Potential challenges and roadblocks are identified. The possible conflict between normal science and decision support is briefly investigated; it is pointed out that “post-normal science” may be a more appropriate description of such processes than simply “science”.

  6. The purpose of adaptation.

    Science.gov (United States)

    Gardner, Andy

    2017-10-06

    A central feature of Darwin's theory of natural selection is that it explains the purpose of biological adaptation. Here, I: emphasize the scientific importance of understanding what adaptations are for, in terms of facilitating the derivation of empirically testable predictions; discuss the population genetical basis for Darwin's theory of the purpose of adaptation, with reference to Fisher's 'fundamental theorem of natural selection'; and show that a deeper understanding of the purpose of adaptation is achieved in the context of social evolution, with reference to inclusive fitness and superorganisms.

  7. Collecting and Analyzing Stakeholder Feedback for Signing at Complex Interchanges

    Science.gov (United States)

    2014-10-01

    The purpose of this project was to identify design constraints related to signing, markings, and geometry for complex interchanges, and then to identify useful topics for future research that will yield findings that can address those design issues. ...

  8. Recent advances in hopanoids analysis: Quantification protocols overview, main research targets and selected problems of complex data exploration.

    Science.gov (United States)

    Zarzycki, Paweł K; Portka, Joanna K

    2015-09-01

    Pentacyclic triterpenoids, particularly hopanoids, are organism-specific compounds and are generally considered as useful biomarkers that allow fingerprinting and classification of biological, environmental and geological samples. Simultaneous quantification of various hopanoids together with battery of related non-polar and low-molecular mass compounds may provide principal information for geochemical and environmental research focusing on both modern and ancient investigations. Target compounds can be derived from microbial biomass, water columns, sediments, coals, crude fossils or rocks. This create number of analytical problems due to different composition of the analytical matrix and interfering compounds and therefore, proper optimization of quantification protocols for such biomarkers is still the challenge. In this work we summarizing typical analytical protocols that were recently applied for quantification of hopanoids like compounds from different samples. Main steps including components of interest extraction, pre-purification, fractionation, derivatization and quantification involving gas (1D and 2D) as well as liquid separation techniques (liquid-liquid extraction, solid-phase extraction, planar and low resolution column chromatography, high-performance liquid chromatography) are described and discussed from practical point of view, mainly based on the experimental papers that were published within last two years, where significant increase in hopanoids research was noticed. The second aim of this review is to describe the latest research trends concerning determination of hopanoids and related low-molecular mass lipids analyzed in various samples including sediments, rocks, coals, crude oils and plant fossils as well as stromatolites and microbial biomass cultivated under different conditions. It has been found that majority of the most recent papers are based on uni- or bivariate approach for complex data analysis. Data interpretation involves

  9. Center for Plant and Microbial Complex Carbohydrates at the University of Georgia Complex Carbohydrate Research Center: Progress Report for the Funding Period November 1, 2002 - October 31, 2003

    Energy Technology Data Exchange (ETDEWEB)

    Albersheim, Peter [Univ. of Georgia, Athens, GA (United States); Darvill, Alan [Univ. of Georgia, Athens, GA (United States)

    2003-10-31

    This progress report describes the research, service, and training activities conducted with the support of the DOE center grant. The research activities are summarized in the form of reprints or abstracts of 46 papers citing support from the DOE center grant that were produced during the reporting period. These papers include those that are published, in press, submitted, or in preparation. The papers include those produced entirely by CCRC personnel and those papers representing research work conducted in collaboration with scientists at other institutions. (See Appendix I.) A major component of this grant is to provide service to researchers at other academic institutions and industries located throughout the US and other parts of the world. A summary of all our service activities during the reporting period is also included with this report, including samples of poly/oligosaccharides and antibodies distributed to scientists (see Appendix II). A description of the three training courses held at the CCRC during 2003 is also provided, together with the names and affiliations of participants who attended the courses (see Appendix III).

  10. Impact of Moist Physics Complexity on Tropical Cyclone Simulations from the Hurricane Weather Research and Forecast System

    Science.gov (United States)

    Kalina, E. A.; Biswas, M.; Newman, K.; Grell, E. D.; Bernardet, L.; Frimel, J.; Carson, L.

    2017-12-01

    The parameterization of moist physics in numerical weather prediction models plays an important role in modulating tropical cyclone structure, intensity, and evolution. The Hurricane Weather Research and Forecast system (HWRF), the National Oceanic and Atmospheric Administration's operational model for tropical cyclone prediction, uses the Scale-Aware Simplified Arakawa-Schubert (SASAS) cumulus scheme and a modified version of the Ferrier-Aligo (FA) microphysics scheme to parameterize moist physics. The FA scheme contains a number of simplifications that allow it to run efficiently in an operational setting, which includes prescribing values for hydrometeor number concentrations (i.e., single-moment microphysics) and advecting the total condensate rather than the individual hydrometeor species. To investigate the impact of these simplifying assumptions on the HWRF forecast, the FA scheme was replaced with the more complex double-moment Thompson microphysics scheme, which individually advects cloud ice, cloud water, rain, snow, and graupel. Retrospective HWRF forecasts of tropical cyclones that occurred in the Atlantic and eastern Pacific ocean basins from 2015-2017 were then simulated and compared to those produced by the operational HWRF configuration. Both traditional model verification metrics (i.e., tropical cyclone track and intensity) and process-oriented metrics (e.g., storm size, precipitation structure, and heating rates from the microphysics scheme) will be presented and compared. The sensitivity of these results to the cumulus scheme used (i.e., the operational SASAS versus the Grell-Freitas scheme) also will be examined. Finally, the merits of replacing the moist physics schemes that are used operationally with the alternatives tested here will be discussed from a standpoint of forecast accuracy versus computational resources.

  11. The Influence of Chinese College Teachers' Competence for Purpose Support on Students' Purpose Development

    Science.gov (United States)

    Jiang, Fei; Lin, Shan; Mariano, Jenni Menon

    2016-01-01

    Research studies agree on the role formal education can play in facilitating students building a sense of life purpose. This paper examined the influence of Chinese college students' perceived competence of their teachers for supporting purpose on these same college students' purpose status. Portions of the Revised Youth Purpose Survey were…

  12. Risk Management in Complex Construction Projects that Apply Renewable Energy Sources: A Case Study of the Realization Phase of the Energis Educational and Research Intelligent Building

    Science.gov (United States)

    Krechowicz, Maria

    2017-10-01

    Nowadays, one of the characteristic features of construction industry is an increased complexity of a growing number of projects. Almost each construction project is unique, has its project-specific purpose, its own project structural complexity, owner’s expectations, ground conditions unique to a certain location, and its own dynamics. Failure costs and costs resulting from unforeseen problems in complex construction projects are very high. Project complexity drivers pose many vulnerabilities to a successful completion of a number of projects. This paper discusses the process of effective risk management in complex construction projects in which renewable energy sources were used, on the example of the realization phase of the ENERGIS teaching-laboratory building, from the point of view of DORBUD S.A., its general contractor. This paper suggests a new approach to risk management for complex construction projects in which renewable energy sources were applied. The risk management process was divided into six stages: gathering information, identification of the top, critical project risks resulting from the project complexity, construction of the fault tree for each top, critical risks, logical analysis of the fault tree, quantitative risk assessment applying fuzzy logic and development of risk response strategy. A new methodology for the qualitative and quantitative risk assessment for top, critical risks in complex construction projects was developed. Risk assessment was carried out applying Fuzzy Fault Tree analysis on the example of one top critical risk. Application of the Fuzzy sets theory to the proposed model allowed to decrease uncertainty and eliminate problems with gaining the crisp values of the basic events probability, common during expert risk assessment with the objective to give the exact risk score of each unwanted event probability.

  13. Combining purpose with profits

    NARCIS (Netherlands)

    Birkinshaw, J.; Foss, N.J.; Lindenberg, S.M.

    2014-01-01

    Is it possible for a company to strive for a higher purpose while also delivering solid profits? Some have argued that pursuing goals other than making money means, by definition, spending on things that aren't profit-maximizing. Others have countered that by investing in worthwhile causes the

  14. Meaningful and Purposeful Practice

    Science.gov (United States)

    Clementi, Donna

    2014-01-01

    This article describes a graphic, designed by Clementi and Terrill, the authors of "Keys to Planning for Learning" (2013), visually representing the components that contribute to meaningful and purposeful practice in learning a world language, practice that leads to greater proficiency. The entire graphic is centered around the letter…

  15. Modeling a nuclear reactor for experimental purposes

    International Nuclear Information System (INIS)

    Berta, V.T.

    1980-01-01

    The Loss-of-Fluid Test (LOFT) Facility is a scale model of a commercial PWR and is as fully functional and operational as the generic commercial counterpart. LOFT was designed and built for experimental purposes as part of the overall NRC reactor safety research program. The purpose of LOFT is to assess the capability of reactor safety systems to perform their intended functions during occurrences of off-normal conditions in a commercial nuclear reactor. Off-normal conditions arising from large and small break loss-of-coolant accidents (LOCA), operational transients, and anticipated transients without scram (ATWS) were to be investigated. This paper describes the LOFT model of the generic PWR and summarizes the experiments that have been conducted in the context of the significant findings involving the complex transient thermal-hydraulics and the consequent effects on the commercial reactor analytical licensing techniques. Through these techniques the validity of the LOFT model as a scaled counterpart of the generic PWR is shown

  16. Forced migrants involved in setting the agenda and designing research to reduce impacts of complex emergencies: combining Swarm with patient and public involvement.

    Science.gov (United States)

    Brainard, Julii Suzanne; Al Assaf, Enana; Omasete, Judith; Leach, Steve; Hammer, Charlotte C; Hunter, Paul R

    2017-01-01

    The UK's National Institute for Health Research (NIHR) Health Protection Research Unit in Emergency Preparedness and Response was asked to undertake research on how to reduce the impact of complex national/international emergencies on public health. How to focus the research and decide on priority topics was challenging, given the nature of complex events. Using a type of structured brain-storming, the researchers identified the ongoing UK, European and international migration crisis as both complex and worthy of deeper research. To further focus the research, two representatives of forced migrant communities were invited to join the project team as patient and public (PPI) representatives. They attended regular project meetings, insightfully contributed to and advised on practical aspects of potential research areas. The representatives identified cultural obstacles and community needs and helped choose the final research study design, which was to interview forced migrants about their strategies to build emotional resilience and prevent mental illness. The representatives also helped design recruitment documents, and undertake recruitment and interviewer training. Many events with wide-ranging negative health impacts are notable for complexity: lack of predictability, non-linear feedback mechanisms and unexpected consequences. A multi-disciplinary research team was tasked with reducing the public health impacts from complex events, but without a pre-specified topic area or research design. This report describes using patient and public involvement within an adaptable but structured development process to set research objectives and aspects of implementation. An agile adaptive development approach, sometimes described as swarm , was used to identify possible research areas. Swarm is meant to quickly identify strengths and weaknesses of any candidate project, to accelerate early failure before resources are invested. When aspects of the European migration crisis

  17. Routinely-collected general practice data are complex, but with systematic processing can be used for quality improvement and research

    Directory of Open Access Journals (Sweden)

    Simon de Lusignan

    2006-03-01

    Conclusions Routinely collected primary care data could contribute more to the process of health improvement; however, those working with these data need to understand fully the complexity of the context within which data entry takes place.

  18. Implementation of the Inter-disciplinary research complex in the L.N. Gumilev Eurasian State University is the step to a modern knowledge intensive technologies

    International Nuclear Information System (INIS)

    Shkol'nik, V.S.; Zholdasbekov, M.Zh.; Kadyrzhanov, K.K.; Itkis, M.G.; Dmitriev, S.N.

    2003-01-01

    In the book the rationale for the Inter-disciplinary research complex implementation in the L.N. Gumilev Eurasian State University (Astana city, Kazakhstan) is given. The design of key facility of the complex - the heavy ion accelerator (DC-60) is described. Application of nuclear membranes as an integrating factor for development of a new technologies, science and a knowledge intensive business is discussed. In these concerns the problems of an industrial technologies development with use of the nano- and microstructures on the nuclear membranes base are considered. The items of the scientific environment formation on the Inter-disciplinary research complex are analyzed. The book is intended for engineers, postgraduates and students specializing in the field of nuclear physics, radiation solid state physics, physics of films and coatings, accelerator technique, material modification with use of charged particles beams

  19. Complexity Plots

    KAUST Repository

    Thiyagalingam, Jeyarajan

    2013-06-01

    In this paper, we present a novel visualization technique for assisting the observation and analysis of algorithmic complexity. In comparison with conventional line graphs, this new technique is not sensitive to the units of measurement, allowing multivariate data series of different physical qualities (e.g., time, space and energy) to be juxtaposed together conveniently and consistently. It supports multivariate visualization as well as uncertainty visualization. It enables users to focus on algorithm categorization by complexity classes, while reducing visual impact caused by constants and algorithmic components that are insignificant to complexity analysis. It provides an effective means for observing the algorithmic complexity of programs with a mixture of algorithms and black-box software through visualization. Through two case studies, we demonstrate the effectiveness of complexity plots in complexity analysis in research, education and application. © 2013 The Author(s) Computer Graphics Forum © 2013 The Eurographics Association and Blackwell Publishing Ltd.

  20. "We're Trying to Take Action": Transformative Agency, Role Re-Mediation, and the Complexities of Youth Participatory Action Research

    Science.gov (United States)

    Bertrand, Melanie; Durand, E. Sybil; Gonzalez, Taucia

    2017-01-01

    This article seeks to illuminate the complexity of youth participatory action research (YPAR) through the use of two concepts: (1) transformative agency, a collective initiative to address conflicts and contradictions in activity systems, and (2) role re-mediation, the disruption of power relations. We demonstrate that these concepts, in…

  1. Coastal coho salmon research in the West Fork Smith River: Patterns of coho salmon size and survival within a complex watershed

    Science.gov (United States)

    Effective habitat restoration planning requires the ability to anticipate fish population responses to altered habitats. The EPA has conducted network-scale research to document habitat-specific growth and survival of juvenile salmonids in a complex watershed. These findings ha...

  2. Fit-for-Purpose

    DEFF Research Database (Denmark)

    Enemark, Stig

    2013-01-01

    ; completeness to cover the total jurisdiction; and credibility in terms of reliable data being trusted by the users. Accuracy can then be incrementally improved over time when relevant and justified by serving the needs of citizen, business and society in general. Such a fit-for-purpose approach is fundamental...... systems act within adopted land policies that define the legal regulatory pattern for dealing with land issues. Land administration systems - whether highly advanced or very basic – require a spatial framework to operate. This framework provides the fundamental information for dealing with land issues...... concepts may well be seen as the end target but not as the point of entry. When assessing the technology and investment choices the focus should be on building a fit-for-purpose framework that will meet the needs of society today and that can be incrementally improved over time....

  3. Purposeful engineering economics

    CERN Document Server

    Chadderton, Ronald A

    2015-01-01

    This textbook/course supplement stands as a unique and highly original complement to the traditional engineering economics curriculum. Its primarily narrative approach conveys the essence of an “Austrian" economic perspective on cash flow analysis and decision making in engineering, without extensive tables and graphs, and requires very little mathematics. The book’s objective is to add a new perspective to the usual study of cash flow analysis and solely econometric engineering decision making. The author draws on the methodology of the Austrian Economists—a school of economic thought that bases its study of economic phenomena on the interpretation and analysis of the purposeful actions of individuals. The book includes an array of illustrative case studies examined in detail by the author and emphasizes the importance of market processes and price signals to coordinate engineering plans. Purposeful Engineering Economics is an ideal resource for students, teaching faculty, and practicing professional ...

  4. Vitalism, purpose and superstition.

    Science.gov (United States)

    Lindeman, Marjaana; Saher, Marieke

    2007-02-01

    Developmental studies have shown that children assign purpose to objects more liberally than adults, and that they explain biological processes in terms of vitalistic causality. This study tested the hypothesis that similar misconceptions can be found among superstitious adults. The results from 116 superstitious and 123 sceptical individuals showed that more than sceptics, superstitious individuals attributed purpose to objects, and explained biological processes in terms of organ intentionality and energy transmission. In addition, they thought of energy as a vital force, attributing life and mental properties to it. These conceptual confusions were positively associated to all types of superstitions as well as belief in alternative medicine. The results support the argument that category mistakes and ontological confusions underlie superstitious and vitalistic thinking.

  5. The purpose of astronomy

    OpenAIRE

    Davoust, Emmanuel

    1995-01-01

    This is a presentation of the purpose of astronomy in the context of modern society. After exposing two misconceptions about astronomy, I detail its role in five domains, certified knowledge, incorporated abilities, innovations, collective goods, and popular science; with each domain is associated an institution, an incentive, and a method of evaluation. Finally, I point out the role of astronomy as a source of inspiration in other fields than science.

  6. Methodological approach in determination of small spatial units in a highly complex terrain in atmospheric pollution research: the case of Zasavje region in Slovenia.

    Science.gov (United States)

    Kukec, Andreja; Boznar, Marija Z; Mlakar, Primoz; Grasic, Bostjan; Herakovic, Andrej; Zadnik, Vesna; Zaletel-Kragelj, Lijana; Farkas, Jerneja; Erzen, Ivan

    2014-05-01

    The study of atmospheric air pollution research in complex terrains is challenged by the lack of appropriate methodology supporting the analysis of the spatial relationship between phenomena affected by a multitude of factors. The key is optimal design of a meaningful approach based on small spatial units of observation. The Zasavje region, Slovenia, was chosen as study area with the main objective to investigate in practice the role of such units in a test environment. The process consisted of three steps: modelling of pollution in the atmosphere with dispersion models, transfer of the results to geographical information system software, and then moving on to final determination of the function of small spatial units. A methodology capable of designing useful units for atmospheric air pollution research in highly complex terrains was created, and the results were deemed useful in offering starting points for further research in the field of geospatial health.

  7. Research on the Governance Mechanism of Aviation Complex Product Manufacturing Supply Chain Based on Dynamic Game Theory

    Directory of Open Access Journals (Sweden)

    Wang Nan

    2016-01-01

    Full Text Available In the manufacturing process of aeronautical complex products, for the following problems: develop long production cycle, a large number of ancillary products, a plurality of participating units, etc, and the status of the frequency of quality problems, using single-phase static game model in the case of asymmetric information, study on Supplier Quality insufficient investment, which resulting in opportunistic behaviour reasons. And using KMRW dynamic game model, we quantitative analysis the mechanism and crucial role of reputation mechanisms to ensure aeronautical complex product manufacturing supply chain and effective operation.

  8. Endeavor research into evolving paradigms around ophiolites: the case of the oceanic igneous complexes of Costa Rica

    International Nuclear Information System (INIS)

    Alvarado, Guillermo E.; Denyer, Perci; Gazel, Esteban

    2009-01-01

    Studies on the radiolarite igneous (ophiolitic) complexes were done for more than one century in Costa Rica that range from Jurassic to Eocene. These studies can be grouped in four stages of knowledge: 1) from 1904 to 1957 were recognized the cherts, and the mafic and ultramafic igneous complexes, the first regional maps were done, and the first time were recognized ellipsoidal basalts, now widely known as pillow lavas. 2) From 1958 to 1978 the complexes were seen under the concept of the association of ophiolites (serpentine, gabbro, diabase, basalts, and related rocks) and interpreted the radiolarites as deep-sea sediments. The stage is characterized by the seminal work of Gabriel Dengo and by the first geochemical analyses in the framework of the plate tectonics. 3) A huge amount of geochemical data, paleontological and K/Ar ages were published from 1979 to 1994 and it was the stage of more controversial papers, their interpretation varied for the same locality (i.e. (Nicoya Peninsula) from relative simple stratigraphic model to a very complex nappe slices, and from a simple tectonic evolution (in situ and formed by a mid oceanic ridge volcanism) to a multistage evolution (terrains, and mid oceanic ridge, aseismic ridge, intraplate and island arc volcanism). The situation was similar in the other Costa Rican oceanic complexes. 4) The outlook for 1995 to the present it has been clarified and mutual agreement between the different groups. The stage is characterized by joint collaboration, the use of modern laboratory techniques as Sr, Nd, and Pb isotopes, major, trace and complete rare earth elements. 40A r/ 39 Ar dating, and volcanological criteria, together with detailed field mapping. The main new result of these studies was that the radiolarites (164-84 Ma) in the Nicoya Peninsula were significatively older than the basic igneous rocks (140-84 Ma), indicating a complex magmatic event intruding and erupting into the thick sedimentary sequence. For other areas

  9. Purpose of the workshop

    International Nuclear Information System (INIS)

    Brunner, H.

    1998-01-01

    The main purpose of the Workshop is to share the experience on emergency data management and to review various conceptual, technical, organisational and operational aspects and problems. The problems posed by hardware and software, the interplay of software developers and users/operators and the positive and negative experiences both from development and operation of data management systems are discussed. Emergency data management systems and their demonstrations are divided into four classes of possible applications: video games, training and simulation systems, 'history writing' = post-event analysis and documentation systems, real-time operational systems. (author)

  10. Detection of irradiated constituents in processed food with complex lipid matrices. Results of a research project of Baden-Wuerttemberg

    International Nuclear Information System (INIS)

    Hartmann, M.; Ammon, J.; Berg, H.

    1999-01-01

    The detection of irradiated constituents in processed food with a complex lipid matrix can be adversely affected by two conditions. The small amounts of radiation-induced hydrocarbons are diluted by the fat matrix of the food, or there are substances accompanying the lipids in the matrix and thus make the analysis more difficult. In those cases, sample preparation alone by means of Florisil SPE (solid-phase extraction) is not enough and requires additional, subsequent SPE argentation chromatography of the Florisil eluate, as this latter analytical method permits reliable detection down to very small amounts of irradiated, fat-containing constituents even in a complex lipid matrix. SPE-Florisil/argentation chromatography detects and selects radiation-induced hydrocarbons in a complex lipid matrix, so that detection of irradiation at even very low doses down to 0.025 kGy is possible. The method described is highly sensitive, inexpensive, and easy to apply. It efficiently substitutes such complex preparation or measuring methods as SFE-GC/MS or LC-GC/MS. This highly sensitive testing method for detection of food irradiation can be carried out in almost any analytical laboratory. (orig./CB) [de

  11. How do ligands influence the quantum yields of cyclometalated platinum(ii) complexes, a theoretical research study.

    Science.gov (United States)

    Yang, Baozhu; Huang, Shuang; Wang, Jianhao

    2017-08-30

    A series of cyclometalated platinum(ii) complexes have been investigated with the TDDFT method. These complexes have similar structures but distinct phosphorescence quantum yields. Theoretical calculations were carried out to explain the differences in quantum yields from the conjugation effect of the cyclometalated ligand, molecular rigidity and ligand-field strength of the monodentate ligand. The radiative decay rate constants (k r ) have been discussed with the oscillator strength (f n ), the strength of the spin-orbit coupling (SOC) interaction between the lowest energy triplet excited state (T 1 ) and singlet excited states (S n ), and the energy gaps between E(T 1 ) and E(S n ). To illustrate the nonradiative decay processes, the transition states (TS) between the triplet metal-centered state ( 3 MC) and T 1 states have been optimized. In addition, the minimum energy crossing points (MECPs) between 3 MC and the ground states (S 0 ) were optimized. Finally, the potential energy curves along the nonradiative decay pathways are simulated. To obtain a phosphorescent complex with a high quantum yield, the complex should retain molecular rigidity well in the S 1 and T 1 states, while showing significant structural distortion at the MECP structure.

  12. On the effects of sampling, analysis and interpretation strategies for complex forensic DNA research with focus on sexual assault cases

    NARCIS (Netherlands)

    Benschop, C.C.G.

    2012-01-01

    Forensisch DNA-onderzoek kan een grote bijdrage leveren aan het oplossen van diverse soorten misdrijven. Dit DNA-onderzoek kan complex zijn, bijvoorbeeld als de hoeveelheid celmateriaal minimaal is of als het biologische spoor celmateriaal bevat van meerdere (aan elkaar verwante) donoren. Corina

  13. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-03-02

    Mar 2, 2015 ... Joseph Daniels1,&, Ruth Nduati1,2, James Kiarie1,3, Carey Farquhar1,4,5 .... or basic science research career (Socio-Behavioral Research, .... a research environment that supports knowledge sharing to develop research ...

  14. Research

    African Journals Online (AJOL)

    students to grasp the complexity of socioeconomic determinants in health. It must explicitly ... and continue to graduate students who lack the competencies to address these challenges. ... centres or hospitals in the SA public sector. A minority ...

  15. Solar stills for agricultural purposes

    Science.gov (United States)

    Selcuk, M. K.; Tran, V. V.

    1975-01-01

    Basic concepts of using desalinated water for agricultural purposes are outlined. A mathematical model describing heat and mass transfer in a system combining a solar still with a greenhouse, its solution, and test results of a small-scale unit built at the Middle East Technical University, Ankara, Turkey, are discussed. The unit was employed to demonstrate the technical feasibility of the system. Further development and modifications are necessary for larger-scale operations. The basis of an optimization study which is underway at the Brace Research Institute of McGill University in Montreal, Canada, aimed at finding the best combination of design and operation parameters is also presented.

  16. Coopetition and Complexity : Exploring a Coopetitive Relationship with Complexity

    OpenAIRE

    Wennberg, Andreas; Persson, Emil

    2011-01-01

    Cooperation have in previous research been seen as a negative impact on competition and  vice versa. This thesis is building on a concept called coopetition in which cooperation and  competition is studied simultaneously. Coopetition have been studied in terms of the level of  cooperation and competition. However, we found a possible link between coopetition and  complexity in previous literature. Thus, the purpose of this study is to explore whether  complexity can develop an understanding f...

  17. An Action Research to Optimize the Well-Being of Older People in Nursing Homes: Challenges and Strategies for Implementing a Complex Intervention.

    Science.gov (United States)

    Bourbonnais, Anne; Ducharme, Francine; Landreville, Philippe; Michaud, Cécile; Gauthier, Marie-Andrée; Lavallée, Marie-Hélène

    2018-03-01

    Few studies have been conducted on strategies to promote the implementation of complex interventions in nursing homes (NHs). This article presents a pilot study intended to assess the strategies that would enable the optimal implementation of a complex intervention approach in NHs based on the meanings of screams of older people living with Alzheimer's disease. An action research approach was used with 19 formal and family caregivers from five NHs. Focus groups and individual interviews were held to assess different implementation strategies. A number of challenges were identified, as were strategies to overcome them. These latter included interactive training, intervention design, and external support. This study shows the feasibility of implementing a complex intervention to optimize older people's well-being. The article shares strategies that may promote the implementation of these types of interventions in NHs.

  18. Ghost Hunting with Lollies, Chess and Lego: Appreciating the "Messy" Complexity (and Costs) of Doing Difficult Research in Education

    Science.gov (United States)

    Graham, Linda J.; Buckley, Linda

    2014-01-01

    This paper contributes to conversations about the funding and quality of education research. The paper proceeds in two parts. Part I sets the context by presenting an historical analysis of funding allocations made to Education research through the ARC's Discovery projects scheme between the years 2002 and 2014, and compares these trends to…

  19. Complexity, Contextualism, and Multiculturalism: Responses to the Critiques and Future Directions for the Gender Role Conflict Research Program

    Science.gov (United States)

    O'Neil, James M.

    2008-01-01

    The author reacts to three reviews by Carolyn Enns, Stephen Wester, and P. Paul and Mary Heppner on "The Counseling Psychologist" Major Contribution "Summarizing 25 Years of Research on Men's Gender Role Conflict Using the Gender Role Conflict Scale: New Research Paradigms and Clinical Implications." The reviews provide support for assessing the…

  20. Utilising Enterprise Risk Management Strategies to Develop a Governance and Operations Framework for a New Research Complex: A Case Study

    Science.gov (United States)

    Clyde-Smith, Jodi

    2014-01-01

    Enterprise risk management strategies were used to develop a regulatory and operational framework for a new multi-partner Research Institute that will house up to 900 staff from four different institutions in Queensland, Australia. The Institute will operate in a business environment while functioning as a research resource for the higher…

  1. Synthesis, crystal structure and computational chemistry research of a Zinc(II complex: [Zn(Pt(Biim2

    Directory of Open Access Journals (Sweden)

    Teng Fei

    2012-01-01

    Full Text Available The title metal-organic coordination complex [Zn(pt(Biim2] (pt=phthalic acid, benzene-1,2-dicarboxylate, Biim=2,2'-biimidazole 1 has been obtained by using hydrothermal synthesis and characterized by single-crystal X-ray diffraction. The complex crystallizes in monoclinic, space group P21/n with a = 8.5466(15 Å, b = 11.760(2 Å, c = 20.829(4 Å, β = 95.56(2º, V = 2083.5(6 Å3, Mr =497.78, Dc = 1.587 g/cm3, μ(MoKα = 1.226 mm−1, F(000 = 1016, Z = 4, the final R = 0.0564 and wR = 0.1851 for 3656 observed reflections (I > 2σ(I. The elemental analysis, IR, TG and the theoretical calculation were also investigated.

  2. A diagnostic evaluation model for complex research partnerships with community engagement: The partnership for Native American Cancer Prevention (NACP) model

    OpenAIRE

    Trotter, Robert T.; Laurila, Kelly; Alberts, David; Huenneke, Laura F.

    2014-01-01

    Complex community oriented health care prevention and intervention partnerships fail or only partially succeed at alarming rates. In light of the current rapid expansion of critically needed programs targeted at health disparities in minority populations, we have designed and are testing an “logic model plus” evaluation model that combines classic logic model and query based evaluation designs (CDC, NIH, Kellogg Foundation) with advances in community engaged designs derived from industry-univ...

  3. Selection of the DC-60 cyclotron as the basic facility for the Inter-disciplinary research complex in the L.N. Gumilev Eurasian State University. Chapter 2

    International Nuclear Information System (INIS)

    2003-01-01

    In the Chapter 2 the DC-60 specialized accelerator project of the Inter-disciplinary research complex in the L.N. Gumilev Eurasian State University is described. The DC-60 cyclotron is intended for applied studies which can be accomplished on both the ion beams of the electron cyclotron resonance source with voltage up to 25 kV and the accelerated ions from carbon to xenon. The cyclotron is design on the base of compact magnet with weight about 74 tonnes, and it mean magnetic field is 1.6 T, section angle - 50 Deg. Design of the Inter-disciplinary research complex building in the L.N. Gumilev Eurasian State University is described as well. Technical performances of the building and their parameters are given

  4. The Jules Horowitz nuclear complex a plat-form for research and development on nuclear fuel and materials for the 21st century

    International Nuclear Information System (INIS)

    Ballagny, A.; Bouilloux, Y.; Chantoin, P.; Iracane, D.

    2001-01-01

    The CEA intends to build a material test reactor at Cadarache (South of France). This reactor would be the central piece of a wider complex which would include experimental fuel fabrication, destructive and non destructive examinations, in-reactor on line measurement advanced methods and modelling. For 50 years this platform would provide the necessary knowledge to the nuclear industry, the safety authority and to the national decision makers. This material test reactor called Jules Horowitz reactor (JHR) could be a key facility for industry and the central component of the European research area on nuclear fission from 2010. In this paper an overview of the research complex is given and a first approach of the development effort undertaken to meet the requirements in term of : ''time to result, experimental cost, experiment quality and international co-operation. Finally are given several ways of technical development undertaken to meet the above requirements. (orig.)

  5. Subgroup complexes

    CERN Document Server

    Smith, Stephen D

    2011-01-01

    This book is intended as an overview of a research area that combines geometries for groups (such as Tits buildings and generalizations), topological aspects of simplicial complexes from p-subgroups of a group (in the spirit of Brown, Quillen, and Webb), and combinatorics of partially ordered sets. The material is intended to serve as an advanced graduate-level text and partly as a general reference on the research area. The treatment offers optional tracks for the reader interested in buildings, geometries for sporadic simple groups, and G-equivariant equivalences and homology for subgroup complexes.

  6. Change in plan for installation of nuclear reactor in No.1 atomic powered vessel of Japan Atomic Energy Research Institute (change in purpose of use and in method for nuclear reactor installation and spent fuel disposal) (report)

    International Nuclear Information System (INIS)

    1987-01-01

    This report, compiled by the Nuclear Safety Commission to be submitted to the Prime Minister, deals with studies concerning some changes in the plan for the installation of a nuclear reactor in the No.1 atomic powered vessel to be constructed under the Japan Atomic Energy Research Institute (changes in the purpose of its use and in the methods for the nuclear reactor installation and spent fuel disposal). The conclusions of and procedures for the examination and evaluation are presented and then detailes of the studies are described. The study on the location requirements for the incidental land facilities at Sekinehama covers various conditions concerning the location, geology, earthquakes, meteorology, hydrology and social environment. The study on the safety design of the nuclear reactor facilities deals with the reactor, fuel handling facilities and other auxiliary facilities, as well as various land facilities to be constructed at Sekinehama including the reactor facilities and other facilities for fuel handling, waste disposal and protection and management of radioactive rays. Evaluation of possible radiation emission is shown and the accident analysis is also addressed. (Nogami, K.)

  7. Enrolling HIV-positive adolescents in mental health research: A case study reflecting on legal and ethical complexities

    Directory of Open Access Journals (Sweden)

    Nataly Woollett

    2017-08-01

    Full Text Available Background. Adolescents living with HIV are an emerging group in the global HIV/AIDS epidemic. Mental health in this population affects HIV care, treatment, consequential morbidity and secondary transmission. There is a paucity of research regarding these youth in South Africa (SA, partly because section 71 of the National Health Act of 2003 (NHA requires parental or guardian’s consent. Objective. To explore legal and ethical issues related to conducting adolescent mental health research in SA. Methods. After obtaining a High Court order permitting research on minors aged <18 years without prior parental or guardian’s consent, we used qualitative and quantitative methods to interview adolescents in five clinics serving HIV-positive adolescents in Johannesburg. Results. Our study enrolled 343 participants; 74% were orphaned and did not have legal guardians, 27% were symptomatic for depression, anxiety or post-traumatic stress disorder, 24% were suicidal, and almost 90% did not feel that they belonged in the family with which they lived. Without court intervention, most of the participants could not have participated in this research because parental consent was impossible to obtain. This case study argues for exceptions to the parental consent requirement, which excludes orphaned and vulnerable children and youth from research. Conclusions. Recommendations are made to promote ethical integrity in conducting mental health research with adolescents. A balance is needed between protecting adolescents from exploitation and permitting access to benefits of research. Requiring parental consent for all research does not necessarily give effect to policy. For the vast majority of SA HIV-positive adolescents, parental consent is not possible. Section 71 of the NHA ought to be amended to facilitate valuable and necessary research concerning HIV-positive orphan children and adolescents.

  8. Research

    African Journals Online (AJOL)

    A descriptive qualitative research design was used to determine whether participants ... simulation as a teaching method; a manikin offering effective learning; confidence ..... Tesch R. Qualitative Research: Analysis Types and Software Tools.

  9. 7 CFR 3430.201 - Purpose.

    Science.gov (United States)

    2010-01-01

    ...-GENERAL AWARD ADMINISTRATIVE PROVISIONS Specialty Crop Research Initiative § 3430.201 Purpose. (a) Focus areas. The purpose of this program is to address the critical needs of the specialty crop industry by developing and disseminating science-based tools to address needs of specific crops and their regions...

  10. A new multi-purpose NIM module

    International Nuclear Information System (INIS)

    Dong Binjiang; Wang Congrong; Du Chunxiang.

    1992-01-01

    The authors briefly state the function, character and main technique performance of a new multi-purpose NIM interposition (NI01) developed recently. This interposition uses 8031 single-chip microprocessors as the kernel and is multi-purpose, reliable and convenient. Especially, it is suitable for training teaching and scientific researching

  11. The complex remuneration of human resources for health in low-income settings: policy implications and a research agenda for designing effective financial incentives.

    Science.gov (United States)

    Bertone, Maria Paola; Witter, Sophie

    2015-07-28

    Human resources for health represent an essential component of health systems and play a key role to accelerate progress towards universal health coverage. Many countries in sub-Saharan Africa face challenges regarding the availability, distribution and performance of health workers, which could be in part addressed by providing effective financial incentives. Based on an overview of the existing literature, the paper highlights the gaps in the existing research in low-income countries exploring the different components of health workers' incomes. It then proposes a novel approach to the analysis of financial incentives and delineates a research agenda, which could contribute to shed light on this topic. The article finds that, while there is ample research that investigates separately each of the incomes health workers may earn (for example, salary, fee-for-service payments, informal incomes, "top-ups" and per diems, dual practice and non-health activities), there is a dearth of studies which look at the health workers' "complex remuneration", that is, the whole of the financial incentives available. Little research exists which analyses simultaneously all revenues of health workers, quantifies the overall remuneration and explores its complexity, its multiple components and their features, as well as the possible interaction between income components. However, such a comprehensive approach is essential to fully comprehend health workers' incentives, by investigating the causes (at individual and system level) of the fragmentation in the income structure and the variability in income levels, as well as the consequences of the "complex remuneration" on motivation and performance. This proposition has important policy implications in terms of devising effective incentive packages as it calls for an active consideration of the role that "complex remuneration" plays in determining recruitment, retention and motivation patterns, as well as, more broadly, the

  12. Research

    African Journals Online (AJOL)

    research process, as part of which students must find and appraise evidence from research.[5] This highlights that teaching research methodology is inclined towards equipping students ... Students believed that evidence-based practice was vital, yet their understanding of the concept was restricted when compared with the.

  13. Managing uncertainty for sustainability of complex projects

    DEFF Research Database (Denmark)

    Brink, Tove

    2017-01-01

    Purpose – The purpose of this paper is to reveal how management of uncertainty can enable sustainability of complex projects. Design/methodology/approach – The research was conducted from June 2014 to May 2015 using a qualitative deductive approach among operation and maintenance actors in offshore...... wind farms. The research contains a focus group interview with 11 companies, 20 individual interviews and a seminar presenting preliminary findings with 60 participants. Findings – The findings reveal the need for management of uncertainty through two different paths. First, project management needs...... to join efforts. Research limitations/implications – Further research is needed to reveal the generalisability of the findings in other complex project contexts containing “unknown unknowns”. Practical implications – The research leads to the development of a tool for uncertainty management...

  14. Complex Topographic Feature Ontology Patterns

    Science.gov (United States)

    Varanka, Dalia E.; Jerris, Thomas J.

    2015-01-01

    Semantic ontologies are examined as effective data models for the representation of complex topographic feature types. Complex feature types are viewed as integrated relations between basic features for a basic purpose. In the context of topographic science, such component assemblages are supported by resource systems and found on the local landscape. Ontologies are organized within six thematic modules of a domain ontology called Topography that includes within its sphere basic feature types, resource systems, and landscape types. Context is constructed not only as a spatial and temporal setting, but a setting also based on environmental processes. Types of spatial relations that exist between components include location, generative processes, and description. An example is offered in a complex feature type ‘mine.’ The identification and extraction of complex feature types are an area for future research.

  15. The punishment's purpose

    Directory of Open Access Journals (Sweden)

    Gheorghe DIACONU

    2012-12-01

    Full Text Available The repressive reaction involves, as any human action, a certain finality. As the punishment's essence is the suffering, then, in the course of time it has been arisen the question regarding the goal for which the society utilizes the suffering and for what the society punishes. According to the classic penal doctrine that bases on the idea of retribution, the repressive reaction was limited to a simple revenge and it didn't existed any concern in order to influence the doer's future behaviour. In the positivist conception, the punishment's purpose was to shelter the society against the offender's new attacks. Going up to an extreme point with this idea, the positivists equated the punishment with the curative treatment at which the patients in the hospitals were submitted and which it was adequate to each category of offender. For the positivists, the penal sanction, it was meant to combat the organic or the psychological anomalies or the dysfunctions of the social environment that have influenced the offender and that determined him to commit antisocial deeds. In the modern vision, the punishment cannot have a goal on its own and that is to answer to bad with bad because it doesn't come from an abstract desire for revenge, but from a concrete necessity of hindering the repetition of the antisocial deeds and of defending the fundamental social values.

  16. Drilling for scientific purpose

    Energy Technology Data Exchange (ETDEWEB)

    Tanaka, Shoichi

    1987-09-01

    Drilling for scientific purpose is a process of conducting geophysical exploration at deep underground and drilling for collecting crust samples directly. This is because earth science has advanced to get a good understanding about the top of the crust and has shifted its main interest to the lower layer of the crust in land regions. The on-land drilling plan in Japan has just started, and the planned drilling spots are areas around the Minami River, Hidaka Mts., kinds of the Mesozoic and Cenozoic granite in outside zone, the extension of Japan Sea, Ogasawara Is., Minami-Tori Is., and active volcanos. The paper also outlines the present situation of on-land drilling in the world, focusing on the SG-3rd super-deep well SG-3 on the Kola Peninsula, USSR, Satori SG-1st well SG-1 in Azerbaidzhan S.S.R, V.S.S.R, Sweden's wells, Cyprus' wells, Bayearn well Plan in West Germany, and Salton Sea Scientific Drilling Program in the U.S. At its end, the paper explains the present situation and the future theme of the Japanese drilling technique and points out the necessity of developing equipment, and techniques. (14 figs, 5 tabs, 26 refs)

  17. Research

    African Journals Online (AJOL)

    abp

    24 juin 2015 ... Page number not for citation purposes. 1. Epaisseur de l'intima-média carotidienne et facteurs de risque cardio-vasculaires. Nicolas Fanantenana Herinirina1, Lova Hasina Ny Ony Narindra Rajaonarison2,&, Andry Roussel Herijoelison3, Ahmad Ahmad2. 1Service Imagerie Médicale, Centre Hospitalier ...

  18. Research

    African Journals Online (AJOL)

    abp

    2013-09-15

    Sep 15, 2013 ... chamber systems. A temporary pacemaker was used in only 1 patient. The cephalic vein was never used for venous access, access being the left subclavian ..... Page number not for citation purposes 11. Figure. 4: Snapshot of pacemaker database shower pacemaker check form. Figure. 5: Distribution in.

  19. Research

    African Journals Online (AJOL)

    One of the guiding principles of the teaching and performance of a medical intervention is to 'firstly do no harm'. Gaining access to a patient's circulatory system for the purpose of administering fluid and/or medications is commonly achieved through a procedure that involves piercing of the skin with a needle and inserting a ...

  20. Research

    African Journals Online (AJOL)

    assigned to a different rural community, with the purpose of working with ... Objective. To assess the students' self-reported perception and effectiveness of the precommunity placement LDP at MUST and its impact during ... change in the task accomplishment skills, interpersonal relationship skills and quality of leadership.

  1. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-10-20

    Oct 20, 2015 ... counties. The area had 105 public and private health facilities [25]. There were three Comprehensive EmOC facilities, one public, and two private facilities, all located in Malindi town [12]. This study was conducted in six facilities from different sites, purposively selected with the assistance of the District ...

  2. Research

    African Journals Online (AJOL)

    [2,3] The definition of a rural-origin student. (ROS) has come under some debate, but for the purpose of this study ... The language of teaching and learning for students not studying in their mother tongue has been seen to pose problems ... trend towards e-learning. Students not previously exposed to this level of technology ...

  3. The purpose of education

    DEFF Research Database (Denmark)

    Thingstrup, Signe Hvid; Schmidt, Lene Skytthe Kaarsberg; Andersen, Randi Nygård

    2017-01-01

    and social approach to learning and wellbeing. This article examines how teachers and pedagogues in an action research project negotiate their new common work and which understandings of good pedagogical practice these negotiations express. The article shows that international educational rationales about...... learnification and attainment that are found in the Danish reform, affect the professionals’ understandings of professionalism and educational practices, and that this marginalises some traditional pedagogical practices. However, the article also shows that both pedagogues and teachers critique dominant...... educational policy rationales and explore what space for action exists in the reform....

  4. Research on the development efficiency of regional high-end talent in China: A complex network approach.

    Science.gov (United States)

    Zhang, Zhen; Wang, Minggang; Tian, Lixin; Zhang, Wenbin

    2017-01-01

    In this paper, based on the panel data of 31 provinces and cities in China from 1991 to 2016, the regional development efficiency matrix of high-end talent is obtained by DEA method, and the matrix is converted into a continuous change of complex networks through the construction of sliding window. Using a series of continuous changes in the complex network topology statistics, the characteristics of regional high-end talent development efficiency system are analyzed. And the results show that the average development efficiency of high-end talent in the western region is at a low level. After 2005, the national regional high-end talent development efficiency network has both short-range relevance and long-range relevance in the evolution process. The central region plays an important intermediary role in the national regional high-end talent development system. And the western region has high clustering characteristics. With the implementation of the high-end talent policies with regional characteristics by different provinces and cities, the relevance of high-end talent development efficiency in various provinces and cities presents a weakening trend, and the geographical characteristics of high-end talent are more and more obvious.

  5. Research

    African Journals Online (AJOL)

    abp

    2017-10-25

    Oct 25, 2017 ... Africa has established oncology health care services but also has low cancer awareness, poor cancer ... recommendations for the improvement of cancer control strategies. .... travel needs, all illustrate the complex nature of physical and ..... with traditional leaders and healers is an appropriate response to.

  6. Research

    African Journals Online (AJOL)

    Kimberley Hospital Complex is a 657-bed tertiary healthcare facility in the Northern Cape ... imperative to obtain a baseline profile of the potential clinician teachers at the institution. ... Community-based education relies heavily on family ... qualifications were obtained in Cuba (n=5), Pakistan (n=3), Brazil, Ghana,. Nigeria ...

  7. Multi-purpose reactor

    International Nuclear Information System (INIS)

    1991-05-01

    The Multi-Purpose-Reactor (MPR), is a pool-type reactor with an open water surface and variable core arrangement. Its main feature is plant safety and reliability. Its power is 22MW t h, cooled by light water and moderated by beryllium. It has platetype fuel elements (MTR type, approx. 20%. enriched uranium) clad in aluminium. Its cobalt (Co 60 ) production capacity is 50000 Ci/yr, 200 Ci/gr. The distribution of the reactor core and associated control and safety systems is essentially based on the following design criteria: - upwards cooling flow, to waive the need for cooling flow inversion in case the reactor is cooled by natural convection if confronted with a loss of pumping power, and in order to establish a superior heat transfer potential (a higher coolant saturation temperature); - easy access to the reactor core from top of pool level with the reactor operating at full power, in order to facilitate actual implementation of experiments. Consequently, mechanisms associated to control and safety rods s,re located underneath the reactor tank; - free access of reactor personnel to top of pool level with the reactor operating at full power. This aids in the training of personnel and the actual carrying out of experiments, hence: - a vast water column was placed over the core to act as radiation shielding; - the core's external area is cooled by a downwards flow which leads to a decay tank beyond the pool (for N 16 to decay); - a small downwards flow was directed to stream downwards from above the reactor core in order to drag along any possibly active element; and - a stagnant hot layer system was placed at top of pool level so as to minimize the upwards coolant flow rising towards pool level

  8. Meta-Analysis With Complex Research Designs: Dealing With Dependence From Multiple Measures and Multiple Group Comparisons

    Science.gov (United States)

    Scammacca, Nancy; Roberts, Greg; Stuebing, Karla K.

    2013-01-01

    Previous research has shown that treating dependent effect sizes as independent inflates the variance of the mean effect size and introduces bias by giving studies with more effect sizes more weight in the meta-analysis. This article summarizes the different approaches to handling dependence that have been advocated by methodologists, some of which are more feasible to implement with education research studies than others. A case study using effect sizes from a recent meta-analysis of reading interventions is presented to compare the results obtained from different approaches to dealing with dependence. Overall, mean effect sizes and variance estimates were found to be similar, but estimates of indexes of heterogeneity varied. Meta-analysts are advised to explore the effect of the method of handling dependence on the heterogeneity estimates before conducting moderator analyses and to choose the approach to dependence that is best suited to their research question and their data set. PMID:25309002

  9. The complexities of 'otherness': reflections on embodiment of a young White British woman engaged in cross-generation research involving older people in Indonesia.

    Science.gov (United States)

    Norris, Meriel

    2015-05-01

    If interviews are to be considered embodied experiences, than the potential influence of the embodied researcher must be explored. A focus on specific attributes such as age or ethnicity belies the complex and negotiated space that both researcher and participant inhabit simultaneously. Drawing on empirical research with stroke survivors in an ethnically mixed area of Indonesia, this paper highlights the importance of considering embodiment as a specific methodological concern. Three specific interactions are described and analysed, illustrating the active nature of the embodied researcher in narrative production and development. The intersectionality of embodied features is evident, alongside their fluctuating influence in time and place. These interactions draw attention to the need to consider the researcher within the interview process and the subsequent analysis and presentation of narrative findings. The paper concludes with a reinforcement of the importance of ongoing and meaningful reflexivity in research, a need to consider the researcher as the other participant, and specifically a call to engage with and present the dynamic nature of embodiment.

  10. Governance of complex environmental situations through social learning: a synthesis of SLIM's lessons for research, policy and practice

    NARCIS (Netherlands)

    Steyaert, P.; Jiggins, Janice

    2007-01-01

    This synthesis of the SLIM project findings deals with the development and deployment of knowledge and research that is useful for actions that transform at socially and ecologically meaningful scales. A diagnostic framework (DF) is elaborated that aims to transform the findings into a tool that

  11. Report on the Research Activities Done for the Project 73209 - Mathematics of Complex Dynamical Systems, Second Part

    National Research Council Canada - National Science Library

    Grigolini, Paolo

    2005-01-01

    ...)---The Physics of non-Poisson processes. The original motivation for the research work, whose results are here illustrated, is the conflict between the ordinary approaches to non-equilibrium statistically physics, based on the time evolution of a bunch of trajectories, density perspective, and the approach based on the time evolution of an individual trajectory, with erratic and unpredictable jumps, trajectory perspective.

  12. A diagnostic evaluation model for complex research partnerships with community engagement: the partnership for Native American Cancer Prevention (NACP) model.

    Science.gov (United States)

    Trotter, Robert T; Laurila, Kelly; Alberts, David; Huenneke, Laura F

    2015-02-01

    Complex community oriented health care prevention and intervention partnerships fail or only partially succeed at alarming rates. In light of the current rapid expansion of critically needed programs targeted at health disparities in minority populations, we have designed and are testing an "logic model plus" evaluation model that combines classic logic model and query based evaluation designs (CDC, NIH, Kellogg Foundation) with advances in community engaged designs derived from industry-university partnership models. These approaches support the application of a "near real time" feedback system (diagnosis and intervention) based on organizational theory, social network theory, and logic model metrics directed at partnership dynamics, combined with logic model metrics. Copyright © 2014 Elsevier Ltd. All rights reserved.

  13. Using Video Game Telemetry Data to Research Motor Chunking, Action Latencies, and Complex Cognitive-Motor Skill Learning.

    Science.gov (United States)

    Thompson, Joseph J; McColeman, C M; Stepanova, Ekaterina R; Blair, Mark R

    2017-04-01

    Many theories of complex cognitive-motor skill learning are built on the notion that basic cognitive processes group actions into easy-to-perform sequences. The present work examines predictions derived from laboratory-based studies of motor chunking and motor preparation using data collected from the real-time strategy video game StarCraft 2. We examined 996,163 action sequences in the telemetry data of 3,317 players across seven levels of skill. As predicted, the latency to the first action (thought to be the beginning of a chunked sequence) is delayed relative to the other actions in the group. Other predictions, inspired by the memory drum theory of Henry and Rogers, received only weak support. Copyright © 2017 Cognitive Science Society, Inc.

  14. [Research on compatibility of prescriptions including Ginseng Radix et Rhizoma and Trogopterus Dung based on complex network analysis].

    Science.gov (United States)

    Li, Meng-Wen; Fan, Xin-Sheng; Zhang, Ling-Shan; Wang, Cong-Jun

    2017-09-01

    The applications of prescriptions including Ginseng Radix et Rhizoma and Trogopterus Dung in contemporary literatures from 1949 to 2016 are compiled and the data mining techniques containing scale-free complex network method are utilized to explore its practical characteristics, with comparison between modern and ancient ones. The results indicate that malignant neoplasms, coronary heart disease which present Qi deficiency and blood stasis type are the main diseases treated by prescriptions including Ginseng Radix et Rhizoma and Trogopterus Dung according to the reports during 1949 to 2016. The complex network connection shows that Glycyrrhizae Radixet Rhizoma, Angelicae Sinensis Radix, Astragali Radix, Typhae Pollen, Salviae Miltiorrhizae Radix et Rhizoma are the primary drugs related to Ginseng Radix et Rhizoma and Trogopterus Dung. The next are Paeoniae Radix Alba, Atractylodis Macrocephalae Rhizoma, Persicae Semen, Foria, et al. Carthami Flos, Notoginseng Radix et Rhizoma, Cyperi Rhizoma, Bupleuri Radix are the peripheral ones. Also, Ginseng Radix et Rhizoma-Glycyrrhizae Radixet Rhizoma, Trogopterus Dung-Glycyrrhizae Radixet Rhizoma, Ginseng Radix et Rhizoma-Angelicae Sinensis Radix, Trogopterus Dung-Angelicae Sinensis Radix, Ginseng Radix et Rhizoma-Astragali Radix, Trogopterus Dung-Astragali Radix are the main paired drugs. The paired drugs including Ginseng Radix et Rhizoma-Trogopterus Dung-Glycyrrhizae Radixet Rhizoma, Ginseng Radix et Rhizoma-Trogopterus Dung-Angelicae Sinensis Radix, Ginseng Radix et Rhizoma-Trogopterus Dung-Astragali Radix, Ginseng Radix et Rhizoma-Trogopterus Dung-Typhae Pollen have a higher support degree. The main compatible drugs are different in ancient and modern prescriptions including Ginseng Radix et Rhizoma and Trogopterus Dung. Notoginseng Radix et Rhizoma, Typhae Pollen, Salviae Miltiorrhizae Radix et Rhizoma, Astragali Radix are utilized frequently in modern prescriptions while less used in ancient ones. It is also shown

  15. Research

    African Journals Online (AJOL)

    abp

    26 janv. 2014 ... Page number not for citation purposes. 1. Morbidité et mortalité hospitalière des maladies .... défini comme le fait de fumer au moins une cigarette par jour. Mesures des paramètres biochimiques ..... 58(suppll1):S3-S5. PubMed | Google Scholar. 23. Levi F, Chatenoud L, Bertuccio P, Lucchini F, Negri E, La.

  16. Research

    African Journals Online (AJOL)

    raoul

    16 févr. 2012 ... Page number not for citation purposes. 1. Prévalence du ... cigarettes. L'initiation du tabagisme à souvent été tardive (21,5 ans) et la dépendance est absente ou faible chez 33% des fumeurs. Les personnes pensent que ..... Idrissi Hassaria E. Tabagisme dans les structures sanitaires à Laayoune. Mémoire ...

  17. Research

    African Journals Online (AJOL)

    raoul

    10 oct. 2011 ... Page number not for citation purposes. 1. Faible taux de succès .... l'âge moyen de la première cigarette était de 18 ± 5 ans [13-35]. Le premier contact avec le .... Grenier O, Cambou JP, Ferrieres J, Thomas D, Amelineau E, Cantet C, Danchin N. Caractéristiques initiales et prise en charge thérapeutique de ...

  18. Research

    African Journals Online (AJOL)

    abp

    16 oct. 2015 ... Page number not for citation purposes. 1. Prévalence de l'hypertension artérielle dans ..... PAD de 9 mm Hg après une cigarette dans un groupe d'hypertendu. Ceci montre l'influence du tabac sur la pression .... Burhole E Masumbuko,Daniel Lemogoum, Zacharie M. Kashongwe, Jean-Paul Degaute, Jeff M ...

  19. Research

    African Journals Online (AJOL)

    2014-05-06

    May 6, 2014 ... facilitate and support articulation between the ECT mid-level worker qualification and the professional B EMC degree. Methods. The researchers used an exploratory, sequential mixed-method design, which is characterised by a qualitative phase of research followed by a quantitative phase. This design is ...

  20. Research

    African Journals Online (AJOL)

    supports medical education and research at institutions in 12 ... (CBE). CapacityPlus, led by IntraHealth International, is the USAID-funded ... acquire public health, clinical, and/or research skills, usually through applied learning in a .... If students were evaluated, indicate the type of student (i.e. medical, dental, nursing, etc.) ...

  1. Research

    African Journals Online (AJOL)

    abp

    2017-01-24

    Jan 24, 2017 ... and the specific rotavirus VP4 (P-types) and VP7 (G-types) determined. Results: The .... Centre for Virus Research (CVR) of the Kenya Medical Research. Institute (KEMRI) ... rotavirus dsRNA was run on 10% polyacrylamide resolving gels using a large format .... What is known about this topic. •. Rotavirus is ...

  2. Research

    African Journals Online (AJOL)

    ebutamanya

    29 mai 2015 ... Diagnostic moléculaire du complexe Mycobacterium tuberculosis résistant à ... 1Centre de Recherche Biomoléculaire Pietro Annigoni, CERBA/LABIOGENE, Université de ... Les résistances à la Rifampicine et à l'Isoniazide ont été étudiées par la technique de la PCR en .... leur statut sérologique au VIH-1.

  3. BHPR research: qualitative1. Complex reasoning determines patients' perception of outcome following foot surgery in rheumatoid arhtritis

    OpenAIRE

    Backhouse, Michael R.; Vinall, Karen A.; Redmond, Anthony; Helliwell, Philip; Keenan, Anne-Maree; Dale, Rebecca M.; Thomas, Amanda; Aronson, Diane; Turner-Cobb, Julie; Sengupta, Raj; France, Brisa; Hill, Ingrid; Flurey, Caroline A.; Morris, Marianne; Pollock, Jon

    2017-01-01

    Background: Foot surgery is common in patients with RA but research into surgical outcomes is limited and conceptually flawed as current outcome measures lack face validity: to date no one has asked patients what is important to them. This study aimed to determine which factors are important to patients when evaluating the success of foot surgery in RA Methods: Semi structured interviews of RA patients who had undergone foot surgery were conducted and transcribed verbatim. Thematic analysis o...

  4. Handling Large and Complex Data in a Photovoltaic Research Institution Using a Custom Laboratory Information Management System

    Energy Technology Data Exchange (ETDEWEB)

    White, Robert R.; Munch, Kristin

    2014-01-01

    Twenty-five years ago the desktop computer started becoming ubiquitous in the scientific lab. Researchers were delighted with its ability to both control instrumentation and acquire data on a single system, but they were not completely satisfied. There were often gaps in knowledge that they thought might be gained if they just had more data and they could get the data faster. Computer technology has evolved in keeping with Moore’s Law meeting those desires; however those improvements have of late become both a boon and bane for researchers. Computers are now capable of producing high speed data streams containing terabytes of information; capabilities that evolved faster than envisioned last century. Software to handle large scientific data sets has not kept up. How much information might be lost through accidental mismanagement or how many discoveries are missed through data overload are now vital questions. An important new task in most scientific disciplines involves developing methods to address those issues and to create the software that can handle large data sets with an eye towards scalability. This software must create archived, indexed, and searchable data from heterogeneous instrumentation for the implementation of a strong data-driven materials development strategy. At the National Center for Photovoltaics in the National Renewable Energy Laboratory, we began development a few years ago on a Laboratory Information Management System (LIMS) designed to handle lab-wide scientific data acquisition, management, processing and mining needs for physics and materials science data, and with a specific focus towards future scalability for new equipment or research focuses. We will present the decisions, processes, and problems we went through while building our LIMS system for materials research, its current operational state and our steps for future development.

  5. “The One Who Chases You Away Does Not Tell You Go”: Silent Refusals and Complex Power Relations in Research Consent Processes in Coastal Kenya

    Science.gov (United States)

    Kamuya, Dorcas M.; Theobald, Sally J.; Marsh, Vicki; Parker, Michael; Geissler, Wenzel P.; Molyneux, Sassy C.

    2015-01-01

    Consent processes have attracted significant research attention over the last decade, including in the global south. Although relevant studies suggest consent is a complex negotiated process involving multiple actors, most guidelines assume consent is a one-off encounter with a clear ‘yes’ or ‘no’ decision. In this paper we explore the concept of ‘silent refusals’, a situation where it is not clear whether potential participants want to join studies or those in studies want to withdraw from research, as they were not actively saying no. We draw on participant observation, in-depth interviews and group discussions conducted with a range of stakeholders in two large community based studies conducted by the KEMRI Wellcome Trust programme in coastal Kenya. We identified three broad inter-related rationales for silent refusals: 1) a strategy to avoid conflicts and safeguard relations within households, - for young women in particular—to appear to conform to the wishes of elders; 2) an approach to maintain friendly, appreciative and reciprocal relationships with fieldworkers, and the broader research programme; and 3) an effort to retain study benefits, either for individuals, whole households or wider communities. That refusals and underlying rationales were silent posed multiple dilemmas for fieldworkers, who are increasingly recognised to play a key interface role between researchers and communities in many settings. Silent refusals reflect and reinforce complex power relations embedded in decisions about research participation, with important implications for consent processes and broader research ethics practice. Fieldworkers need support to reflect upon and respond to the ethically charged environment they work in. PMID:25978465

  6. Research

    African Journals Online (AJOL)

    abp

    2017-10-25

    Oct 25, 2017 ... stigma and superstition are known to lead to frequent presentation .... The limited documented research on challenges to help-seeking behaviour for cancer ..... to touch your breast [16] that breast self-examination may cause.

  7. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-10-02

    Oct 2, 2015 ... thought to prevent infection, but recent research has proven otherwise. In addition ... One patient had ophthalmalgia and was exposed to. Kaiy for one year and ... migraine, ear infections, tuberculosis, bone fractures, epilepsy,.

  8. Research

    African Journals Online (AJOL)

    abp

    2016-07-12

    Jul 12, 2016 ... multiple risk factors provides support for multiple-behavior interventions as ... consumption) with smoking therefore needs further research. As such this study .... restaurants, in bars, and on a statewide basis. They preferred to.

  9. Research

    African Journals Online (AJOL)

    The mini-clinical-evaluation exercise (mini-CEX) is a way of assessing the clinical ... Ethical approval for this study was obtained from the Medical Health. Research ..... mini-CEX assessment and feedback session, the greater the likelihood of.

  10. Research

    African Journals Online (AJOL)

    abp

    2016-04-14

    Apr 14, 2016 ... Qualitative data, content analysis approach was used. Results: Overall 422 .... Study design: A mixed method cross-sectional design using both quantitative and qualitative research methods as described by. Hanson et al [33] ...

  11. Research

    International Nuclear Information System (INIS)

    1999-01-01

    Subjects covered in this section are: (1) PCAST panel promotes energy research cooperation; (2) Letter issued by ANS urges funding balance in FFTF restart consideration and (3) FESAC panel releases report on priorities and balance

  12. Research

    African Journals Online (AJOL)

    Research. December 2017, Vol. 9, No. 4 AJHPE 171. During curriculum development, teachers ... Ideally, examiners need an educational method to determine ..... A major focus of this study was addressing the human resource gap when.

  13. Complex research and qualification methods of cement products for the processing, accumulation and storage of radioactive waste

    International Nuclear Information System (INIS)

    Kovalinska, T.; Ostapenko, I.; Sakhno, V.

    2015-01-01

    INR (Ukrainian Institute for Nuclear Research) has developed an installation to assess the degradation of cements and concretes over accelerated time and in hard operating conditions involving mechanical and chemical effects, radiation, high temperatures, electric fields...This testing installation is called a reactionary chamber. The experimental data obtained during these tests characterize the product functionality in the stationary, transitional and emergency modes. These data allow the solving of the equation system representing the state of a product at a current moment of time and to determine its reactions to various external influences. An example is given through the testing of concrete containers that are intended to store radioactive waste

  14. Course evaluation for the purpose of development

    DEFF Research Database (Denmark)

    Nielsen, Tine; Kreiner, Svend

    2017-01-01

    The purpose was to investigate whether it would be useful for development purposes to include a survey of learning styles among student and teachers as part of the evaluation of a graduate course in statistics in a Public Health Programme, and to compare the learning styles of students and lectur......The purpose was to investigate whether it would be useful for development purposes to include a survey of learning styles among student and teachers as part of the evaluation of a graduate course in statistics in a Public Health Programme, and to compare the learning styles of students...... different styles. Results showed differences between the learning styles of teachers and students, and identified two areas for course development: the design of exercises with regard to the level of abstraction and concreteness; the incompatibility of the relatively complex ways of thinking embedded...

  15. Research on the co-movement between high-end talent and economic growth: A complex network approach

    Science.gov (United States)

    Zhang, Zhen; Wang, Minggang; Xu, Hua; Zhang, Wenbin; Tian, Lixin

    2018-02-01

    The major goal of this paper is to focus on the co-movement between high-end talent and economic growth by a complex network approach. Firstly, the national high-end talent development efficiency from 1990 to 2015 is taken as the quantitative index to measure the development of high-end talent. The added values of the primary industry, secondary industry, tertiary industry are selected as economic growth indexes, and all the selected sample data are standardized by the mean value processing method. Secondly, let seven months as the length of the sliding window, and one month as the sliding step, then the grey correlation degrees between systems are measured using the slope correlation degrees, and the grey correlation degree sequence is mapped into the symbol series composed by three symbols { Y , O , N } based on the coarse graining method. Let three characters as a mode, the nodes are obtained by the modes according to the time sequence. Let the transformation between the modal be the edge, and the times of the transformation be weight, then the co-movement networks between national high-end talent development efficiency and the added values of the primary industry, secondary industry, tertiary industry are built respectively. Finally, the dynamic characteristics of the networks are analysed by the node strength, strength distribution, weighted clustering coefficient, conversion cycle of the modes and the transition between the co-movement modes. The results indicate that there are mutual influence and promotion relations between the national high-end talent development efficiency and the added values of the primary, secondary and tertiary industry.

  16. Mixed methods research in the development and evaluation of complex interventions in palliative and end-of-life care: report on the MORECare consensus exercise.

    Science.gov (United States)

    Farquhar, Morag; Preston, Nancy; Evans, Catherine J; Grande, Gunn; Short, Vicky; Benalia, Hamid; Higginson, Irene J; Todd, Chris

    2013-12-01

    Complex interventions are common in palliative and end-of-life care. Mixed methods approaches sit well within the multiphase model of complex intervention development and evaluation. Generic mixed methods guidance is useful but additional challenges in the research design and operationalization within palliative and end-of-life care may have an impact on the use of mixed methods. The objective of the study was to develop guidance on the best methods for combining quantitative and qualitative methods for health and social care intervention development and evaluation in palliative and end-of-life care. A one-day workshop was held where experts participated in facilitated groups using Transparent Expert Consultation to generate items for potential recommendations. Agreement and consensus were then sought on nine draft recommendations (DRs) in a follow-up exercise. There was at least moderate agreement with most of the DRs, although consensus was low. Strongest agreement was with DR1 (usefulness of mixed methods to palliative and end-of-life care) and DR5 (importance of attention to respondent burden), and least agreement was with DR2 (use of theoretical perspectives) and DR6 (therapeutic effects of research interviews). Narrative comments enabled recommendation refinement. Two fully endorsed, five partially endorsed, and two refined DRs emerged. The relationship of these nine to six key challenges of palliative and end-of-life care research was analyzed. There is a need for further discussion of these recommendations and their contribution to methodology. The recommendations should be considered when designing and operationalizing mixed methods studies of complex interventions in palliative care, and because they may have wider relevance, should be considered for other applications.

  17. Complex processing of antimony-mercury gold concentrates of Dzhizhikrut Deposit

    International Nuclear Information System (INIS)

    Abdusalyamova, M.N.; Gadoev, S.A.; Dreisinger, D.; Solozhenkin, P.M.

    2013-01-01

    Present article is devoted to complex processing of antimony-mercury gold concentrates of Dzhizhikrut Deposit. The purpose of research was obtaining the metallic mercury and antimony with further gold and thallium extraction.

  18. Materials and Life Science Experimental Facility at the Japan Proton Accelerator Research Complex III: Neutron Devices and Computational and Sample Environments

    Directory of Open Access Journals (Sweden)

    Kaoru Sakasai

    2017-08-01

    Full Text Available Neutron devices such as neutron detectors, optical devices including supermirror devices and 3He neutron spin filters, and choppers are successfully developed and installed at the Materials Life Science Facility (MLF of the Japan Proton Accelerator Research Complex (J-PARC, Tokai, Japan. Four software components of MLF computational environment, instrument control, data acquisition, data analysis, and a database, have been developed and equipped at MLF. MLF also provides a wide variety of sample environment options including high and low temperatures, high magnetic fields, and high pressures. This paper describes the current status of neutron devices, computational and sample environments at MLF.

  19. Complex and symplectic geometry

    CERN Document Server

    Medori, Costantino; Tomassini, Adriano

    2017-01-01

    This book arises from the INdAM Meeting "Complex and Symplectic Geometry", which was held in Cortona in June 2016. Several leading specialists, including young researchers, in the field of complex and symplectic geometry, present the state of the art of their research on topics such as the cohomology of complex manifolds; analytic techniques in Kähler and non-Kähler geometry; almost-complex and symplectic structures; special structures on complex manifolds; and deformations of complex objects. The work is intended for researchers in these areas.

  20. Research

    African Journals Online (AJOL)

    abp

    2017-05-18

    May 18, 2017 ... available to populations of developing countries [2-5]. In 2013, in. Western and Central Europe and ..... initiation among the infected persons in the community. Addressing stigma and educating ... Lifespan/Tufts/Brown Center for AIDS Research (P30AI042853). Tables. Table 1: Baseline characteristics of ...

  1. Research

    African Journals Online (AJOL)

    abp

    15 févr. 2016 ... présentent un Indice de Masse Corporel (IMC) normal, les autres femmes sont soit ..... In The health belief model and personal health behavior, edited by MH ... Evaluation of the Osteoporosis Health Belief Scale. Research in.

  2. Research

    African Journals Online (AJOL)

    2017-03-14

    Mar 14, 2017 ... R Ebrahim,1 MSc (Dent); H Julie,2 MPH, MCur, PhD. 1 Extended ... and research is applied to develop and sustain society.[5]. Methods .... service they want, not the service we want to give whether they want it or. Co math. G.

  3. Research

    African Journals Online (AJOL)

    abp

    2014-04-21

    Apr 21, 2014 ... Prospective assessment of the risk of obstructive sleep apnea in ... Faculty of Clinical Sciences, College of Medicine, University of .... University Teaching Hospital Health Research Ethics Committee ... BANG, Berlin questionnaire and the American Society of .... The epidemiology of adult obstructive sleep.

  4. Research

    African Journals Online (AJOL)

    abp

    2016-02-01

    Feb 1, 2016 ... University Hospital, DK-5000 Odense, Denmark, 3Center for Global Health, Institute of Clinical Research, University of Southern Denmark, DK-5000. Odense .... BHP is a Danish-Guinean Demographic Surveillance Site with a study-area .... variables such as age groups, previous military duty, history of.

  5. Research

    African Journals Online (AJOL)

    abp

    2015-06-24

    Jun 24, 2015 ... related immunosuppression, previous history of TB, and pause in treatment [6]. In Brazil, researchers .... treatment, use of traditional medicines or herbs, history of TB drug side effects and treatment delay). ..... therapy for pulmonary tuberculosis in Lima Ciudad, Peru. International journal of tuberculosis and ...

  6. Research

    African Journals Online (AJOL)

    Research. May 2016, Vol. 8, No. 1 AJHPE 37. Students who enrol in occupational therapy (OT) at the. University of Kwa Zulu-Natal (UKZN), Durban, South Africa ... The latter may include becoming familiar with the disintegrating social systems in primary .... They also lacked the skills needed to adapt sessions and failed to ...

  7. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-06-22

    Jun 22, 2015 ... collaboration with Makerere University, School of Public Health. We acknowledge The Family Health Research and Development Centre. (FHRDC) Uganda. Supported by Bill & Melinda Gates Institute for. Population & Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, ...

  8. Research

    African Journals Online (AJOL)

    However, a focus on competence alone is inadequate to produce graduates who are capable of adapting to the changing needs of health systems. While knowledge and technical ... shared their responses to guided questions. There were three sessions; after each session the researcher aggregated participant responses ...

  9. Research

    African Journals Online (AJOL)

    abp

    2014-01-31

    Jan 31, 2014 ... by Hazarika in a population-based study in India. The researcher noted that patients' preference to the private health facilities was due mainly to their dissatisfaction with the services in the public health facilities [11]. Furthermore, the quality of the services in the private health facilities could also be a major ...

  10. Research

    African Journals Online (AJOL)

    2018-03-20

    Mar 20, 2018 ... student health professionals in various institutions, both in South Africa. (SA) and internationally. ... field include dentists, dental therapists and oral hygienists in training, .... The College of Health Sciences at UKZN has four schools: clinical ..... Journal of Emerging Trends in Educational Research and Policy ...

  11. Research

    African Journals Online (AJOL)

    abp

    2017-09-14

    Sep 14, 2017 ... Abstract. Introduction: Medical and dental students are a high-risk group for hepatitis B virus (HBV) infection which is an ... The Pan African Medical Journal - ISSN 1937-8688. ... Research ... in the College of Health Sciences and clinical students (years four to .... Hepatology International.2017 Jan; 11(1):.

  12. Research

    African Journals Online (AJOL)

    abp

    2015-01-19

    Jan 19, 2015 ... One research assistant was available to assist the learners and to answer questions while they completed the questionnaires during a classroom period. ..... PubMed | Google Scholar. 4. Hall PA, Holmqvist M, Sherry SB. Risky adolescent sexual behaviour: A psychological perspective for primary care.

  13. The neutron total cross-section measurement of 56Fe and 57Fe by using Japan Proton Accelerator Research Complex facility

    International Nuclear Information System (INIS)

    Kim, Eun Ae; Shvetsov, Valery; Cho, Moo Hyun; Won, Nam Kung; Kim, Kwang Soo; Yang, Sung Chul; Lee, Man Woo; Kim, Guin Yun; Yi, Kyoung Rak; Choi, Hong Yub; Ro, Tae Ik; Mizumoto, Motoharu; Katabuchi, Tatsuya; Igashira, Masayuki

    2012-01-01

    The measurement of neutron cross section using Time-Of-Flight (TOF) method gives significant information for the nuclear data research. In the present work, the neutron total cross section of 56 Fe and 57 Fe has been measured in the energy range between 10 eV and 100 keV by using the neutron beam produced from 3-GeV proton synchrotron accelerator. The 3-GeV proton synchrotron accelerator is located at Japan Proton Accelerator Research Complex (J-PARC) facility in Tokai village. In this study, the neutron total cross section data measured by 6 Li glass scintillator detector was compared with the evaluated values of ENDF/B-VII.0

  14. The neutron total cross-section measurement of {sup 56}Fe and {sup 57}Fe by using Japan Proton Accelerator Research Complex facility

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Eun Ae; Shvetsov, Valery; Cho, Moo Hyun [Pohang University of Science and Technology, Pohang (Korea, Republic of); Won, Nam Kung [Pohang Accelerator Laboratory, Pohang (Korea, Republic of); Kim, Kwang Soo; Yang, Sung Chul; Lee, Man Woo; Kim, Guin Yun [Kyungpook National University, Daegu (Korea, Republic of); Yi, Kyoung Rak; Choi, Hong Yub; Ro, Tae Ik [Dong-A University, Pusan (Korea, Republic of); Mizumoto, Motoharu; Katabuchi, Tatsuya; Igashira, Masayuki [Tokyo Institute of Technology, Tokyo (Japan)

    2012-05-15

    The measurement of neutron cross section using Time-Of-Flight (TOF) method gives significant information for the nuclear data research. In the present work, the neutron total cross section of {sup 56}Fe and {sup 57}Fe has been measured in the energy range between 10 eV and 100 keV by using the neutron beam produced from 3-GeV proton synchrotron accelerator. The 3-GeV proton synchrotron accelerator is located at Japan Proton Accelerator Research Complex (J-PARC) facility in Tokai village. In this study, the neutron total cross section data measured by {sup 6}Li glass scintillator detector was compared with the evaluated values of ENDF/B-VII.0

  15. Analysis of patterns of three-phase bone scintigraphy for patients with complex regional pain syndrome diagnosed using the proposed research criteria (the 'Budapest Criteria').

    Science.gov (United States)

    Moon, J Y; Park, S Y; Kim, Y C; Lee, S C; Nahm, F S; Kim, J H; Kim, H; Oh, S W

    2012-04-01

    Three-phase bone scintigraphy (TPBS) is an established objective diagnostic method for complex regional pain syndrome (CRPS), but its validity remains controversial. The aims of this study were: (i) to re-evaluate the diagnostic performance of TPBS, and (ii) to suggest new TPBS criteria based on the proposed research criteria for CPRS in Budapest (the 2003 Budapest research criteria). The medical records of 228 consecutive patients, evaluated using the Budapest research criteria, were retrospectively analysed. Of these, 116 patients were included in the present study, and 69 of 116 were diagnosed to have CRPS based on these criteria. The diagnostic performance of TPBS was assessed by determining its sensitivity, specificity, and positive and negative likelihood ratios, and new criteria for TPBS were identified by pattern analysis using the Budapest research criteria. The sensitivity, specificity, positive likelihood ratio, and negative likelihood ratio of TPBS for the diagnosis of CRPS according to the Budapest research criteria were 40.0, 76.5, 1.73, and 0.78, respectively. Furthermore, D-D-D, D-D-S, and D-D-I patterns [i.e. according to decreased (D), symmetrical (S), or increased (I) tracer uptake during Phases I, II, and III] of TPBS were found to be positively predictive for CRPS. The diagnostic value of a positive TPBS for CRPS is low from the view point of the Budapest research criteria. Our findings suggest that a diagnosis of CRPS using the Budapest research criteria should be considered when decreased patterns of TPBS are observed during Phases I and II.

  16. Geoarchaeological research of the mid-age Ilyas Bey complex buildings with ground penetrating radar in Miletus, Aydin, Western Anatolia, Turkey

    International Nuclear Information System (INIS)

    Kadioglu, S; Kadioglu, Y K; Akyol, A A

    2008-01-01

    The ancient Miletus which were one of the most important city of ancient Iona, are today of great value from cultural standpoint of Turkey. Miletus, situated near the village of Balat in the present district of Soke was founded on a peninsula, approximately 2.5 km long. In the Byzantine period, the city boundaries were quite reduced. In 1424 Miletus was taken inside of the Ottoman Empire and was completely abandoned in the 17th century. Ancient Miletus excavation studies were first begun in 1899 by in Berlin Museum and interrupted during the World War I. At present, the extensive restoration works in Ilyas Bey Complex has applied as a project since 2006. Ilyas Bey Complex that includes Mosque, Medresah and baths situated on the archaeological area in ancient Miletus. Impressive Mosque built in 1404 by Ilyas Bey, Emir of Menteseogullari founded in 1279 and the complex was named after him, is one of the most remarkable buildings of mid-age Miletus. There are two main purposes of the study are (1) to determine archaeological remains of the study area underneath Ilyas Bey Complex and (2) to define the nature of main rock unit and their sources in the vicinity or Aegean region. After preliminary archaeometrical studies, acquired GPR profile data paralleled each other in Ilyas Bey Mosque and its around, Medresah Courtyard and inner Courtyard of the Mosque. After processing 2D parallel GPR profiles, we constructed 3D data volume by lining processed 2D profiles up to correlate remain signatures from each profile for each studied area. It was obtained transparent 3D visualisation of GPR data by assigning a new colour scale for the amplitude range and by constructing a new opacity function instead of the linear opacity function. Therefore we could successfully image the archaeological remains in an interactive transparent 3D volume and its sub-volumes, starting at different depth levels or limited profiles. The archaeometrical (geological and mineralogical, petrographical

  17. Geoarchaeological research of the mid-age Ilyas Bey complex buildings with ground penetrating radar in Miletus, Aydin, Western Anatolia, Turkey

    Energy Technology Data Exchange (ETDEWEB)

    Kadioglu, S [Ankara University, Eng. Fac. Geophysical Engineering Department, 06100 Ankara (Turkey); Kadioglu, Y K [Ankara University, Eng. Fac. Geological Engineering Department, 06100 Ankara (Turkey); Akyol, A A [Ankara University, Baskent Vac. High Sch. Prog. of Restoration and Cons., Ankara (Turkey)], E-mail: kadioglu@eng.ankara.edu.tr, E-mail: kadi@eng.ankara.edu.tr, E-mail: akyol@ankara.edu.tr

    2008-07-01

    The ancient Miletus which were one of the most important city of ancient Iona, are today of great value from cultural standpoint of Turkey. Miletus, situated near the village of Balat in the present district of Soke was founded on a peninsula, approximately 2.5 km long. In the Byzantine period, the city boundaries were quite reduced. In 1424 Miletus was taken inside of the Ottoman Empire and was completely abandoned in the 17th century. Ancient Miletus excavation studies were first begun in 1899 by in Berlin Museum and interrupted during the World War I. At present, the extensive restoration works in Ilyas Bey Complex has applied as a project since 2006. Ilyas Bey Complex that includes Mosque, Medresah and baths situated on the archaeological area in ancient Miletus. Impressive Mosque built in 1404 by Ilyas Bey, Emir of Menteseogullari founded in 1279 and the complex was named after him, is one of the most remarkable buildings of mid-age Miletus. There are two main purposes of the study are (1) to determine archaeological remains of the study area underneath Ilyas Bey Complex and (2) to define the nature of main rock unit and their sources in the vicinity or Aegean region. After preliminary archaeometrical studies, acquired GPR profile data paralleled each other in Ilyas Bey Mosque and its around, Medresah Courtyard and inner Courtyard of the Mosque. After processing 2D parallel GPR profiles, we constructed 3D data volume by lining processed 2D profiles up to correlate remain signatures from each profile for each studied area. It was obtained transparent 3D visualisation of GPR data by assigning a new colour scale for the amplitude range and by constructing a new opacity function instead of the linear opacity function. Therefore we could successfully image the archaeological remains in an interactive transparent 3D volume and its sub-volumes, starting at different depth levels or limited profiles. The archaeometrical (geological and mineralogical, petrographical

  18. Symptom management in complex post-traumatic stress disorder (ICD-11), view and experience of patients and their relatives: a mixed methods approach (Research Proposal).

    Science.gov (United States)

    Stadtmann, Manuel P; Maercker, Andreas; Binder, Jochen; Schnepp, Wilfried

    2017-09-07

    Using the framework of IDC-11, complex post-traumatic stress disorder will be diagnosed using the core criteria of a post-traumatic stress disorder and the presence of at least one symptom from the following three domains: symptoms of emotional dysregulation, negative self-concept, and problems in interpersonal relationships. In the literature, these symptoms are discussed as a common reason for seeking treatment. The symptoms can influence and impair the quality of life. This article describes a mixed methods study with a sequential exploratory design. The aim is to describe specific patient characteristics, levels of symptom burden and perspectives of adult inpatients and to describe the experiences, views and needs of patients' relatives. The study will also investigate facilitators of and barriers to symptom management. The research will be conducted in four phases. The first phase will assess patients' symptom burdens. The second phase will use semi-structured interviews to explore attitudes to symptom management and perceptions of patients and their relatives. The third phase will statistically explore hypotheses generated after the qualitative interviews. The fourth phase will mix the quantitative and qualitative results and interpret critically. The present study will add new results to the growing literature on complex post-traumatic stress disorder. These results could serve as the basis for further research into the development of interventions to improve symptom management. Trial registration Ethical approval has been obtained from the Swiss cantonal ethic commission (Nr. 201500096). This research was also registered to the World Health Organization Clinical Trials Search Portal through the German Clinical Trial Register, Trial DRKS00012268 (21/04/2017).

  19. Complexity Management - A multiple case study analysis on control and reduction of complexity costs

    DEFF Research Database (Denmark)

    Myrodia, Anna

    of products, with features more custom-made to cover individual needs, both regarding characteristics of products and support services. This necessity leads to a considerable increase of the complexity in the company, which affects the product portfolio, production and supply chain, market segments......, IT systems, and business processes. In order to identify and eliminate complexity, several approaches are used, both by researchers and practitioners. The purpose of this thesis is to contribute to the existing knowledge of complexity management theory. This research focuses on the relationship between......Complexity tends to be arguably the biggest challenge of manufacturing companies. The motivation of further studying complexity is a combination between the existing literature and the practical experiences from the industry. Based on the latest trend companies are trying to supply a growing mix...

  20. Impact of research on policy and practice | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2011-01-31

    Jan 31, 2011 ... ... food and water, worsening migration pressures and possibly increasing the ... as 'a chaos of purposes and accidents', I prefer to use the terms complex, ... poverty in Uganda found that only 2 of 25 were researchable issues.

  1. 'The research compass'

    DEFF Research Database (Denmark)

    Ringsted, Charlotte; Hodges, Brian; Scherpbier, Albert

    2011-01-01

    This AMEE Guide offers an introduction to research in medical education. It is intended for those who are contemplating conducting research in medical education but are new to the field. The Guide is structured around the process of transforming ideas and problems into researchable questions...... by the complexity of the field. Next is a section on how to move from an idea or problem to a research question by placing a concrete idea or problem within a conceptual, theoretical framework. The following sections are structured around an overview model of approaches to medical education research, 'The research......, choosing a research approach that is appropriate to the purpose of the study and considering the individual researcher's preferences and the contextual possibilities and constraints. The first section of the Guide addresses the rationale for research in medical education and some of the challenges posed...

  2. Evaluation and validation of social and psychological markers in randomised trials of complex interventions in mental health: a methodological research programme.

    Science.gov (United States)

    Dunn, Graham; Emsley, Richard; Liu, Hanhua; Landau, Sabine; Green, Jonathan; White, Ian; Pickles, Andrew

    2015-11-01

    The development of the capability and capacity to evaluate the outcomes of trials of complex interventions is a key priority of the National Institute for Health Research (NIHR) and the Medical Research Council (MRC). The evaluation of complex treatment programmes for mental illness (e.g. cognitive-behavioural therapy for depression or psychosis) not only is a vital component of this research in its own right but also provides a well-established model for the evaluation of complex interventions in other clinical areas. In the context of efficacy and mechanism evaluation (EME) there is a particular need for robust methods for making valid causal inference in explanatory analyses of the mechanisms of treatment-induced change in clinical outcomes in randomised clinical trials. The key objective was to produce statistical methods to enable trial investigators to make valid causal inferences about the mechanisms of treatment-induced change in these clinical outcomes. The primary objective of this report is to disseminate this methodology, aiming specifically at trial practitioners. The three components of the research were (1) the extension of instrumental variable (IV) methods to latent growth curve models and growth mixture models for repeated-measures data; (2) the development of designs and regression methods for parallel trials; and (3) the evaluation of the sensitivity/robustness of findings to the assumptions necessary for model identifiability. We illustrate our methods with applications from psychological and psychosocial intervention trials, keeping the technical details to a minimum, leaving the reporting of the more theoretical and mathematically demanding results for publication in appropriate specialist journals. We show how to estimate treatment effects and introduce methods for EME. We explain the use of IV methods and principal stratification to evaluate the role of putative treatment effect mediators and therapeutic process measures. These results are

  3. Humic acids and their interactions with metallic elements: Cu II, Eu III, Th IV, U VI: contribution of size exclusion chromatography method and research of complexation models

    International Nuclear Information System (INIS)

    Lesourd-Moulin, V.

    1986-04-01

    The interest given to natural organic matter (humic and fulvic acids) as complexing agents of metallic ions in soils and natural waters becomes more and more important in environmental area. Cation - humic matter interactions have a great importance, a better understanding of the contribution of these substances in natural media specially towards radioactive elements with long life time. Interactions are studied by a chromatographic technique of gel filtration: the dynamic equilibrium method is based on the separation of the formed complex humic macromolecule - metallic ion and the free metallic ion, which due to its size penetrates totally in the pores of the gel. Separation mechanisms of the chromatographic support and the contribution of each parameter, are studied as a function of the buffer nature, its concentration, the PH, the gel porosity and the valence of the metallic cation. This study led to the determination of the appropriate experimental conditions for each cation. A study of metallic binding with humic acid has been undertaken with Cu 2+ , Eu 3+ , Th 4+ , Uo 2 2+ . These elements, except copper, have been chosen for their properties similar to the transuranic elements. Different samples of humic acids (commercial, podzolic soil, rendzine soil) are also studied. A deeper research of europium - humic acid interactions by means of different treatment models (discrete or gaussian models) has been undertaken in order to determine the number, the binding site strength and the global interaction constants [fr

  4. Research on the Influence of Cutting Rates on Macrogeometry Deflections of Surfaces under Processing Complex form Products Made of Aluminium Aloys

    Directory of Open Access Journals (Sweden)

    Ieva Švagždytė

    2015-03-01

    Full Text Available The article reviews the influence of cutting rates on macrogeometry deflection of milling complex form products and turning an outside surface. For that purpose, one of the most popular aluminium alloys 6082 has been chosen. A ball nose mill of 8 mm in diameter has been milled employing CNC vertical centre HAAS MINI MILL and applying CNC lathe HAAS ST 20 for turning. Measurements have been carried out using coordinate measuring machine DEA micro-hite DCC, applying the probe sphere of 3mm in diameter and the probe equipped with a needle. A deviation of the surface profile from tangent to therophore parabola has been investigated. The determinants R2 of the obtained regressive equation have disclosed that the depth of the cut has the biggest influence on macrogeometry deflections, whereas feed rate has a slighter influence and cutting speed has no radical influence. For the turning process, the depth of the cut has the strongest influence on circularity while cilindrisity has been mainly affected by cutting speed.

  5. A model for restoration of the vegetation complex in the ENEA Trisaia research center; Un modello per il riassetto della vegetazione nel centro di ricerche ENEA della Trisaia

    Energy Technology Data Exchange (ETDEWEB)

    D' Aquino, L.; Pace, S.; Marannino, P. [ENEA, Centro Ricerche Trisaia, Rotondella, MT (Italy). Dipt. Innovazione; Cassano, G. [ENEA, Centro Ricerche Trisaia, Rotondella, MT (Italy). Dipt. Ambiente; Cirio, U. [ENEA, Centro Ricerche Casaccia, Casaccia, S. Maria di Galeria, RM (Italy). Dipt. Innovazione

    1999-07-01

    A model for management of the vegetation complex in the ENEA (National Agency for New Technology, Energy and the Environment) Trisaia research center in Rotondella (Southern Italy), based on the restoration of wild potential vegetation and application of sustainable agriculture practices, is proposed. Benefits on environmental status and vegetation management are discussed. [Italian] Viene presentato un modello di intervento di rsistemazione della vegetazione nel centro di ricerche ENEA della Trisaia di Rotondella (Matera), finalizzato a ricostruire aree di copertura boschiva e a macchia, riconducibili alla vegetazione naturale potenziale del sito, in equilibrio con agrositemi gestiti secondo le tecniche dell'agricoltura sostenibile, e tenendo conto delle esigenze di urbanizzazione del centro. Sono discussi i vantaggi ottenibili dall'applicazione del modello di intervento sull'ambiente locale e sulla gestione del verde.

  6. Current Trends in Korean Adolescents’ Social Purpose

    Directory of Open Access Journals (Sweden)

    Shin Jongho

    2014-06-01

    Full Text Available In the research presented we investigated the features of Korean adolescents’ social purpose as compared with other life goals in terms of different aspects of psychological well-being (study 1. We also examine the perceptions of high achieving Korean adolescents on social purpose and factors affecting it (study 2.The results of study 1 showed that the pursuit of social purpose significantly predicted psychological well-being compared to the other two life goals. Results of study 2 showed Korean adolescents value and pursue social purpose as a life goal. They explicitly accepted their social responsibility to serve their country in line with idyllic Confucianism values and Collectivistic roles. However, further analysis revealed that they had implicitly pursued individualistic desires of materialistic wealth and fame in parallel with their explicit social purpose. Implications of the results are discussed from the socio-cultural perspective on social purpose in regards to how to understand the features of social purpose that Korean adolescents have and how to foster its development.

  7. 7 CFR 3430.901 - Purpose.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Purpose. 3430.901 Section 3430.901 Agriculture Regulations of the Department of Agriculture (Continued) COOPERATIVE STATE RESEARCH, EDUCATION, AND EXTENSION SERVICE, DEPARTMENT OF AGRICULTURE COMPETITIVE AND NONCOMPETITIVE NON-FORMULA FEDERAL ASSISTANCE PROGRAMS...

  8. 32 CFR 249.1 - Purpose.

    Science.gov (United States)

    2010-07-01

    ... OF DoD-RELATED SCIENTIFIC AND TECHNICAL PAPERS AT MEETINGS § 249.1 Purpose. This part amplifies... scientific and technical papers; provides guidance for reviewing and presenting papers containing export... scientific and technical papers; and provides criteria for identifying fundamental research activities...

  9. 42 CFR 93.101 - Purpose.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Purpose. 93.101 Section 93.101 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT General...

  10. Teaching English for Specific Purposes

    Directory of Open Access Journals (Sweden)

    Nijolė Netikšienė

    2011-04-01

    Full Text Available Teaching English for Specific Purposes and General English is analysed in the article. The scientific approach of a scientist M. Rosenberg is presented. The experience of teaching English for Specific Purposesat VGTU is alsopresented. The ideas and teaching methods from the classes of general English can be transferred to the classes of English for Specific Purposes.

  11. Comparison of the new intermediate complex atmospheric research (ICAR) model with the WRF model in a mesoscale catchment in Central Europe

    Science.gov (United States)

    Härer, Stefan; Bernhardt, Matthias; Gutmann, Ethan; Bauer, Hans-Stefan; Schulz, Karsten

    2017-04-01

    Until recently, a large gap existed in the atmospheric downscaling strategies. On the one hand, computationally efficient statistical approaches are widely used, on the other hand, dynamic but CPU-intensive numeric atmospheric models like the weather research and forecast (WRF) model exist. The intermediate complex atmospheric research (ICAR) model developed at NCAR (Boulder, Colorado, USA) addresses this gap by combining the strengths of both approaches: the process-based structure of a dynamic model and its applicability in a changing climate as well as the speed of a parsimonious modelling approach which facilitates the modelling of ensembles and a straightforward way to test new parametrization schemes as well as various input data sources. However, the ICAR model has not been tested in Europe and on slightly undulated terrain yet. This study now evaluates for the first time the ICAR model to WRF model runs in Central Europe comparing a complete year of model results in the mesoscale Attert catchment (Luxembourg). In addition to these modelling results, we also describe the first implementation of ICAR on an Intel Phi architecture and consequently perform speed tests between the Vienna cluster, a standard workstation and the use of an Intel Phi coprocessor. Finally, the study gives an outlook on sensitivity studies using slightly different input data sources.

  12. Selection criteria for patients with chronic ankle instability in controlled research: a position statement of the international ankle consortium

    NARCIS (Netherlands)

    Gribble, P.A.; Delahunt, E.; Bleakley, C.; Caulfield, B.; Docherty, C.L.; Fourchet, F.; Fong, D.; Hertel, J.; Hiller, C.; Kaminski, T.W.; McKeon, P.O.; Refshauge, K.M.; Wees, P.J. van der; Vicenzino, B.; Wikstrom, E.A.

    2013-01-01

    The International Ankle Consortium is an international community of researchers and clinicians whose primary scholastic purpose is to promote scholarship and dissemination of research-informed knowledge related to pathologies of the ankle complex. The constituents of the International Ankle

  13. Procuring complex performance:case: public infrastructure projects

    OpenAIRE

    Leppänen, T. (Tero)

    2015-01-01

    Abstract This research studies procuring complex performance (PCP) in the case of public infrastructure projects. Focus of the research is on the interface between public clients and private sector contractors. Purpose of this research is to find out what are the main challenges of different project delivery methods according to literature (RQ1) and what are the practical challenges of public procurement (RQ2). As an end re...

  14. The evaluation of complex clinical trial protocols: resources available to research ethics committees and the use of clinical trial registries--a case study.

    Science.gov (United States)

    Homedes, Núria; Ugalde, Antonio

    2015-06-01

    To assess the potential role of clinical trial (CT) registries and other resources available to research ethics committees (RECs) in the evaluation of complex CT protocols in low-income and middle-income countries. Using a case study approach, the authors examined the decision-making process of a REC in Argentina and its efforts to use available resources to decide on a complex protocol. We also analysed the information in the USA and other CT registries and consulted 24 CT experts in seven countries. Information requested by the Argentinean REC from other national RECs and ethics' experts was not useful to verify the adequacy of the REC's decision whether or not to approve the CT. The responses from the national regulatory agency and the sponsor were not helpful either. The identification of international resources that could assist was beyond the REC's capability. The information in the USA and other CT registries is limited, and at times misleading; and its accuracy is not verified by register keepers. RECs have limited access to experts and institutions that could assist them in their deliberations. Sponsors do not always answer RECs' request for information to properly conduct the ethical and methodological assessment of CT protocols. The usefulness of the CT registries is curtailed by the lack of appropriate codes and by data errors. Information about reasons for rejection, withdrawal or suspension of the trial should be included in the registries. Establishing formal channels of communication among national and foreign RECs and with independent international reference centres could strengthen the ethical review of CT protocols. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  15. Multi-Purpose Test Stand

    Data.gov (United States)

    Federal Laboratory Consortium — The Multi-Purpose Test Stand is used for a wide variety of tests. The Stand is designed to be rotated through a range of fixed yaw positions to allow engines to be...

  16. NEEDS ANALYSIS IN ENGLISH FOR SPECIFIC PURPOSES

    Directory of Open Access Journals (Sweden)

    SIMION MINODORA OTILIA

    2015-03-01

    Full Text Available Needs analysis is considered to be the cornerstone of English for Specific Purposes(ESP. The concept of Needs analysis has been different along the decades. At the initial stages of ESP( the 1960s and early 1970s, needs analysis consisted in assessing the communicative needs of the learners and the techniques of achieving specific teaching objectives. Nowadays, the tasks of needs analysis is much more complex: it aims at collecting information about the learners and at defining the target situation and environment of studying ESP.

  17. ComplexRec 2017

    DEFF Research Database (Denmark)

    a single step in the user's more complex background need. These background needs can often place a variety of constraints on which recommendations are interesting to the user and when they are appropriate. However, relatively little research has been done on these complex recommendation scenarios....... The ComplexRec 2017 workshop addressed this by providing an interactive venue for discussing approaches to recommendation in complex scenarios that have no simple one-size-fits-all-solution....

  18. Qualitative and quantitative methods in health research

    OpenAIRE

    V?zquez Navarrete, M. Luisa

    2009-01-01

    Introduction Research in the area of health has been traditionally dominated by quantitative research. However, the complexity of ill-health, which is socially constructed by individuals, health personnel and health authorities have motivated the search for other forms to approach knowledge. Aim To discuss the complementarities of qualitative and quantitative research methods in the generation of knowledge. Contents The purpose of quantitative research is to measure the magnitude of an event,...

  19. Health and environmental effects of complex chemical mixtures: proceedings

    Energy Technology Data Exchange (ETDEWEB)

    1985-01-01

    The Office of Health and Environmental Research (OHER) of the Department of Energy supports a broad long-term research program on human health and environmental effects from potential exposure to energy-related complex chemical mixtures. The program seeks basic mechanistic data on the effects of complex mixtures at the cellular, molecular, and whole animal levels to aid in predicting human health effects and seeks ecological data on biological and physical transformations in the mixtures, concentrations of the mixtures in various compartments of the environment, and potential routes for human exposure to these mixtures (e.g., food chain). On June 17-18, 1985, OHER held its First Annual Technical Meeting on the Complex Chemical Mixtures Program in Chicago, IL. The primary purpose of the meeting was to enable principal investigators to report the research status and accomplishments of ongoing complex chemical mixture studies supported by OHER. To help focus future research directions round table discussions were conducted.

  20. From System Complexity to Emergent Properties

    CERN Document Server

    Aziz-Alaoui, M. A

    2009-01-01

    Emergence and complexity refer to the appearance of higher-level properties and behaviours of a system that obviously comes from the collective dynamics of that system's components. These properties are not directly deductable from the lower-level motion of that system. Emergent properties are properties of the "whole'' that are not possessed by any of the individual parts making up that whole. Such phenomena exist in various domains and can be described, using complexity concepts and thematic knowledges. This book highlights complexity modelling through dynamical or behavioral systems. The pluridisciplinary purposes, developped along the chapters, are enable to design links between a wide-range of fundamental and applicative Sciences. Developing such links - instead of focusing on specific and narrow researches - is characteristic of the Science of Complexity that we try to promote by this contribution.

  1. Beam loss reduction by injection painting in the 3-GeV rapid cycling synchrotron of the Japan Proton Accelerator Research Complex

    Directory of Open Access Journals (Sweden)

    H. Hotchi

    2012-04-01

    Full Text Available The 3-GeV rapid cycling synchrotron (RCS of the Japan Proton Accelerator Research Complex was commissioned in October 2007. Via the initial beam tuning and a series of underlying beam studies with low-intensity beams, since December 2009, we have intermittently been performing beam tuning experiments with higher-intensity beams including the injection painting technique. By optimizing the injection painting parameters, we have successfully achieved a 420 kW-equivalent output intensity at a low-level intensity loss of less than 1%. Also the corresponding numerical simulation well reproduced the observed painting parameter dependence on the beam loss, and captured a characteristic behavior of the high-intensity beam in the injection painting process. In this paper, we present the experimental results obtained in the course of the RCS beam power ramp-up, especially on the beam loss reduction achieved by employing the injection painting, together with the numerical simulation results.

  2. First high-power model of the annular-ring coupled structure for use in the Japan Proton Accelerator Research Complex linac

    Directory of Open Access Journals (Sweden)

    Hiroyuki Ao

    2012-01-01

    Full Text Available A prototype cavity for the annular-ring coupled structure (ACS for use in the Japan Proton Accelerator Research Complex (J-PARC linac has been developed to confirm the feasibility of achieving the required performance. This prototype cavity is a buncher module, which includes ten accelerating cells in total. The ACS cavity is formed by the silver brazing of ACS half-cell pieces stacked in a vacuum furnace. The accelerating cell of the ACS is surrounded by a coupling cell. We, therefore, tuned the frequencies of the accelerating and coupling cells by an ultraprecision lathe before brazing, taking into account the frequency shift due to brazing. The prototype buncher module was successfully conditioned up to 600 kW, which corresponds to an accelerating field that is higher than the designed field of 4.1  MV/m by 30%. We describe the frequency-tuning results for the prototype buncher module and its high-power conditioning.

  3. Mixed-Methods Research in a Complex Multisite VA Health Services Study: Variations in the Implementation and Characteristics of Chiropractic Services in VA

    Directory of Open Access Journals (Sweden)

    Raheleh Khorsan

    2013-01-01

    Full Text Available Maximizing the quality and benefits of newly established chiropractic services represents an important policy and practice goal for the US Department of Veterans Affairs’ healthcare system. Understanding the implementation process and characteristics of new chiropractic clinics and the determinants and consequences of these processes and characteristics is a critical first step in guiding quality improvement. This paper reports insights and lessons learned regarding the successful application of mixed methods research approaches—insights derived from a study of chiropractic clinic implementation and characteristics, Variations in the Implementation and Characteristics of Chiropractic Services in VA (VICCS. Challenges and solutions are presented in areas ranging from selection and recruitment of sites and participants to the collection and analysis of varied data sources. The VICCS study illustrates the importance of several factors in successful mixed-methods approaches, including (1 the importance of a formal, fully developed logic model to identify and link data sources, variables, and outcomes of interest to the study’s analysis plan and its data collection instruments and codebook and (2 ensuring that data collection methods, including mixed-methods, match study aims. Overall, successful application of a mixed-methods approach requires careful planning, frequent trade-offs, and complex coding and analysis.

  4. [Alzheimer's disease cerebro-spinal fluid biomarkers: A clinical research tool sometimes useful in daily clinical practice of memory clinics for the diagnosis of complex cases].

    Science.gov (United States)

    Magnin, E; Dumurgier, J; Bouaziz-Amar, E; Bombois, S; Wallon, D; Gabelle, A; Lehmann, S; Blanc, F; Bousiges, O; Hannequin, D; Jung, B; Miguet-Alfonsi, C; Quillard, M; Pasquier, F; Peoc'h, K; Laplanche, J-L; Hugon, J; Paquet, C

    2017-04-01

    The role of biomarkers in clinical research was recently highlighted in the new criteria for the diagnosis of Alzheimer's disease. Cerebro-spinal fluid (CSF) biomarkers (total Tau protein, threonine 181 phosphorylated Tau protein and amyloid Aβ1-42 peptide) are associated with cerebral neuropathological lesions observed in Alzheimer's disease (neuronal death, neurofibrillary tangle with abnormal Tau deposits and amyloid plaque). Aβ1-40 amyloid peptide dosage helps to interpret Aβ1-42 results. As suggested in the latest international criteria and the French HAS (Haute Autorité de santé) recommendations, using theses CSF biomarkers should not be systematic but sometimes could be performed to improve confidence about the diagnostic of Alzheimer's disease in young subjects or in complex clinical situations. Future biomarkers actually in development will additionally help in diagnostic process (differential diagnosis) and in prognostic evaluation of neurodegenerative diseases. Copyright © 2016 Société Nationale Française de Médecine Interne (SNFMI). Published by Elsevier SAS. All rights reserved.

  5. Advances in translational neuropathic research: example of enantioselective pharmacokinetic-pharmacodynamic modeling of ketamine-induced pain relief in complex regional pain syndrome.

    Science.gov (United States)

    Sabia, Michael; Hirsh, Robert A; Torjman, Marc C; Wainer, Irving W; Cooper, Niti; Domsky, Richard; Goldberg, Michael E

    2011-06-01

    Historically, complex regional pain syndrome (CRPS) was poorly defined, which meant that scientists and clinicians faced much uncertainty in the study, diagnosis, and treatment of the syndrome. The problem could be attributed to a nonspecific diagnostic criteria, unknown pathophysiologic causes, and limited treatment options. The two forms of CRPS still are painful, debilitating disorders whose sufferers carry heavy emotional burdens. Current research has shown that CRPS I and CRPS II are distinctive processes, and the presence or absence of a partial nerve lesion distinguishes them apart. Ketamine has been the focus of various studies involving the treatment of CRPS; however, currently, there is incomplete data from evidence-based studies. The question as to why ketamine is effective in controlling the symptoms of a subset of patients with CRPS and not others remains to be answered. A possible explanation to this phenomenon is pharmacogenetic differences that may exist in different patient populations. This review summarizes important translational work recently published on the treatment of CRPS using ketamine. © Springer Science+Business Media, LLC 2011

  6. Direct observation of the phase space footprint of a painting injection in the Rapid Cycling Synchrotron at the Japan Proton Accelerator Research Complex

    Directory of Open Access Journals (Sweden)

    P. K. Saha

    2009-04-01

    Full Text Available The 3 GeV Rapid Cycling Synchrotron (RCS at Japan Proton Accelerator Research Complex is nearly at the operational stage with regard to the beam commissioning aspects. Recently, the design painting injection study has been commenced with the aim of high output beam power at the extraction. In order to observe the phase space footprint of the painting injection, a method was developed utilizing a beam position monitor (BPM in the so-called single pass mode. The turn-by-turn phase space coordinates of the circulating beam directly measured using a pair of BPMs entirely positioned in drift space, and the calculated transfer matrices from the injection point to the pair of BPMs with several successive turns were used together in order to obtain the phase space footprint of the painting injection. There are two such pairs of BPMs placed in two different locations in the RCS, the results from which both agreed and were quite consistent with what was expected.

  7. Direct observation of the phase space footprint of a painting injection in the Rapid Cycling Synchrotron at the Japan Proton Accelerator Research Complex

    Science.gov (United States)

    Saha, P. K.; Shobuda, Y.; Hotchi, H.; Hayashi, N.; Takayanagi, T.; Harada, H.; Irie, Y.

    2009-04-01

    The 3 GeV Rapid Cycling Synchrotron (RCS) at Japan Proton Accelerator Research Complex is nearly at the operational stage with regard to the beam commissioning aspects. Recently, the design painting injection study has been commenced with the aim of high output beam power at the extraction. In order to observe the phase space footprint of the painting injection, a method was developed utilizing a beam position monitor (BPM) in the so-called single pass mode. The turn-by-turn phase space coordinates of the circulating beam directly measured using a pair of BPMs entirely positioned in drift space, and the calculated transfer matrices from the injection point to the pair of BPMs with several successive turns were used together in order to obtain the phase space footprint of the painting injection. There are two such pairs of BPMs placed in two different locations in the RCS, the results from which both agreed and were quite consistent with what was expected.

  8. Using mixed methods research in medical education: basic guidelines for researchers.

    Science.gov (United States)

    Schifferdecker, Karen E; Reed, Virginia A

    2009-07-01

    Mixed methods research involves the collection, analysis and integration of both qualitative and quantitative data in a single study. The benefits of a mixed methods approach are particularly evident when studying new questions or complex initiatives and interactions, which is often the case in medical education research. Basic guidelines for when to use mixed methods research and how to design a mixed methods study in medical education research are not readily available. The purpose of this paper is to remedy that situation by providing an overview of mixed methods research, research design models relevant for medical education research, examples of each research design model in medical education research, and basic guidelines for medical education researchers interested in mixed methods research. Mixed methods may prove superior in increasing the integrity and applicability of findings when studying new or complex initiatives and interactions in medical education research. They deserve an increased presence and recognition in medical education research.

  9. General Purpose (office) Network reorganisation

    CERN Multimedia

    IT Department

    2016-01-01

    On Saturday 27 August, the IT Department’s Communication Systems group will perform a major reorganisation of CERN’s General Purpose Network.   This reorganisation will cause network interruptions on Saturday 27 August (and possibly Sunday 28 August) and will be followed by a change to the IP addresses of connected systems that will come into effect on Monday 3 October. For further details and information about the actions you may need to take, please see: https://information-technology.web.cern.ch/news/general-purpose-office-network-reorganisation.

  10. Investigating the Purpose of Trigonometry in the Modern Sciences

    Science.gov (United States)

    Hertel, Joshua T.

    2013-01-01

    This dissertation reports the results of a qualitative research project that aimed to develop a research-based perspective on the purpose of trigonometry in the modern sciences. The investigation was guided by three objectives. First, the study sought to identify the purpose of trigonometry as described by educators and high school textbooks.…

  11. Demystifying Mixed Methods Research Design: A Review of the Literature

    OpenAIRE

    Gail D. Caruth

    2013-01-01

    Mixed methods research evolved in response to the observed limitations of both quantitative and qualitative designs and is a more complex method. The purpose of this paper was to examine mixed methods research in an attempt to demystify the design thereby allowing those less familiar with its design an opportunity to utilize it in future research. A review of the literature revealed that it has been gaining acceptance among researchers, researchers have begun using mixed methods research, it ...

  12. Complex chemistry

    International Nuclear Information System (INIS)

    Kim, Bong Gon; Kim, Jae Sang; Kim, Jin Eun; Lee, Boo Yeon

    2006-06-01

    This book introduces complex chemistry with ten chapters, which include development of complex chemistry on history coordination theory and Warner's coordination theory and new development of complex chemistry, nomenclature on complex with conception and define, chemical formula on coordination compound, symbol of stereochemistry, stereo structure and isomerism, electron structure and bond theory on complex, structure of complex like NMR and XAFS, balance and reaction on solution, an organo-metallic chemistry, biology inorganic chemistry, material chemistry of complex, design of complex and calculation chemistry.

  13. Reconceptualizing Design Research in the Age of Mobile Learning

    Science.gov (United States)

    Bannan, Brenda; Cook, John; Pachler, Norbert

    2016-01-01

    The purpose of this paper is to begin to examine how the intersection of mobile learning and design research prompts the reconceptualization of research and design individually as well as their integration appropriate for current, complex learning environments. To fully conceptualize and reconceptualize design research in mobile learning, the…

  14. Demystifying Mixed Methods Research Design: A Review of the Literature

    Science.gov (United States)

    Caruth, Gail D.

    2013-01-01

    Mixed methods research evolved in response to the observed limitations of both quantitative and qualitative designs and is a more complex method. The purpose of this paper was to examine mixed methods research in an attempt to demystify the design thereby allowing those less familiar with its design an opportunity to utilize it in future research.…

  15. Analytical purpose electron backscattering system

    International Nuclear Information System (INIS)

    Desdin, L.; Padron, I.; Laria, J.

    1996-01-01

    In this work an analytical purposes electron backscattering system improved at the Center of Applied Studies for Nuclear Development is described. This system can be applied for fast, exact and nondestructive testing of binary and AL/Cu, AL/Ni in alloys and for other applications

  16. Machine Translation for Academic Purposes

    Science.gov (United States)

    Lin, Grace Hui-chin; Chien, Paul Shih Chieh

    2009-01-01

    Due to the globalization trend and knowledge boost in the second millennium, multi-lingual translation has become a noteworthy issue. For the purposes of learning knowledge in academic fields, Machine Translation (MT) should be noticed not only academically but also practically. MT should be informed to the translating learners because it is a…

  17. supplementary foods for weaning purposes

    African Journals Online (AJOL)

    DR. AMINU

    Nigeria. ABSTRACT. The paper focuses on complementary and supplementary foods for weaning purposes. While ... decision, which guides when to introduce semi-solid foods to infants. It considers the .... readiness of many healthy infants. ... foods. However, caution should be exercised .... Attitudes and practices of infants.

  18. Common Courses for Common Purposes:

    DEFF Research Database (Denmark)

    Schaub Jr, Gary John

    2014-01-01

    (PME)? I suggest three alternative paths that increased cooperation in PME at the level of the command and staff course could take: a Nordic Defence College, standardized national command and staff courses, and a core curriculum of common courses for common purposes. I conclude with a discussion of how...

  19. Purposes and Effects of Lying.

    Science.gov (United States)

    Hample, Dale

    Three exploratory studies were aimed at describing the purposes of lies and the consequences of lying. Data were collected through a partly open-ended questionnaire, a content analysis of several tape-recorded interviews, and a large-scale survey. The results showed that two of every three lies were told for selfish reasons, while three of every…

  20. General purpose programmable accelerator board

    Science.gov (United States)

    Robertson, Perry J.; Witzke, Edward L.

    2001-01-01

    A general purpose accelerator board and acceleration method comprising use of: one or more programmable logic devices; a plurality of memory blocks; bus interface for communicating data between the memory blocks and devices external to the board; and dynamic programming capabilities for providing logic to the programmable logic device to be executed on data in the memory blocks.