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Sample records for pulsed endor studies

  1. Simulating suppression effects in Pulsed ENDOR, and the 'hole in the middle' of Mims and Davies ENDOR Spectra.

    Science.gov (United States)

    Doan, Peter E; Lees, Nicholas S; Shanmugam, Muralidharan; Hoffman, Brian M

    2010-01-01

    All pulsed ENDOR techniques, and in particular the Mims and Davies sequences, suffer from detectability biases ('blindspots') that are directly correlated to the size of the hyperfine interactions of coupled nuclei. Our efforts at ENDOR 'crystallography' and 'mechanism determination' with these techniques has led our group to refine our simulations of pulsed ENDOR spectra to take into account these biases, and we here describe the process and illustrate it with several examples. We first focus on an issue whose major significance is not widely appreciated, the 'hole in the middle' of pulsed ENDOR spectra caused by the n = 0 suppression hole in Mims ENDOR and by the analogous A→0 suppression in Davies ENDOR (Section I). This section discusses the issue for nuclei with I = ½ and also for (2)H (I = 1), using the treatment of Section II. In Section II we discuss the general treatment of suppression effects for I = 1, illustrating it with a treatment of Mims suppression for (14)N (I = 1) (Section II).

  2. Arsenic speciation in synthetic gypsum (CaSO4·2H2O): A synchrotron XAS, single-crystal EPR, and pulsed ENDOR study

    Science.gov (United States)

    Lin, Jinru; Chen, Ning; Nilges, Mark J.; Pan, Yuanming

    2013-04-01

    Gypsum (CaSO4·2H2O) is a major by-product of mining and milling processes of borate, phosphate and uranium deposits worldwide and, therefore, potentially plays an important role in the stability and bioavailability of heavy metalloids, including As, in tailings and surrounding areas. Gypsum containing 1900 and 185 ppm As, synthesized with Na2HAsO4·7H2O and NaAsO2 in the starting materials, respectively, have been investigated by synchrotron X-ray absorption spectroscopy (XAS), single-crystal electron paramagnetic resonance spectroscopy (EPR), and pulsed electron nuclear double resonance spectroscopy (ENDOR). Quantitative analyses of As K edge XANES and EXAFS spectra show that arsenic occurs in both +3 and +5 oxidation states and the As3+/As5+ value varies from 0.35 to 0.79. Single-crystal EPR spectra of gamma-ray-irradiated gypsum reveal two types of arsenic-associated oxyradicals: [AsO3]2- and an [AsO2]2-. The [AsO3]2- center is characterized by principal 75As hyperfine coupling constants of A1 = 1952.0(2) MHz, A2 = 1492.6(2) MHz and A3 = 1488.7(2) MHz, with the unique A axis along the S-O1 bond direction, and contains complex 1H superhyperfine structures that have been determined by pulsed ENDOR. These results suggest that the [AsO3]2- center formed from electron trapping on the central As5+ ion of a substitutional (AsO4)3- group after removal of an O1 atom. The [AsO2]2- center is characterized by its unique A(75As) axis approximately perpendicular to the O1-S-O2 plane and the A2 axis along the S-O2 bond direction, consistent with electron trapping on the central As3+ ion of a substitutional (AsO3)3- group after removal of an O2 atom. These results confirm lattice-bound As5+ and As3+ in gypsum and point to potential application of this mineral for immobilization and removal of arsenic pollution.

  3. Quantum Computing Using Pulse-Based Electron-Nuclear Double Resonance (endor):. Molecular Spin-Qubits

    Science.gov (United States)

    Sato, Kazuo; Nakazawa, Shigeki; Rahimi, Robabeh D.; Nishida, Shinsuke; Ise, Tomoaki; Shimoi, Daisuke; Toyota, Kazuo; Morita, Yasushi; Kitagawa, Masahiro; Carl, Parick; Höfner, Peter; Takui, Takeji

    2009-06-01

    Electrons with the spin quantum number 1/2, as physical qubits, have naturally been anticipated for implementing quantum computing and information processing (QC/QIP). Recently, electron spin-qubit systems in organic molecular frames have emerged as a hybrid spin-qubit system along with a nuclear spin-1/2 qubit. Among promising candidates for QC/QIP from the materials science side, the reasons for why electron spin-qubits such as molecular spin systems, i.e., unpaired electron spins in molecular frames, have potentialities for serving for QC/QIP will be given in the lecture (Chapter), emphasizing what their advantages or disadvantages are entertained and what technical and intrinsic issues should be dealt with for the implementation of molecular-spin quantum computers in terms of currently available spin manipulation technology such as pulse-based electron-nuclear double resonance (pulsed or pulse ENDOR) devoted to QC/QIP. Firstly, a general introduction and introductory remarks to pulsed ENDOR spectroscopy as electron-nuclear spin manipulation technology is given. Super dense coding (SDC) experiments by the use of pulsed ENDOR are also introduced to understand differentiating QC ENDOR from QC NMR based on modern nuclear spin technology. Direct observation of the spinor inherent in an electron spin, detected for the first time, will be shown in connection with the entanglement of an electron-nuclear hybrid system. Novel microwave spin manipulation technology enabling us to deal with genuine electron-electron spin-qubit systems in the molecular frame will be introduced, illustrating, from the synthetic strategy of matter spin-qubits, a key-role of the molecular design of g-tensor/hyperfine-(A-)tensor molecular engineering for QC/QIP. Finally, important technological achievements of recently-emerging CD ELDOR (Coherent-Dual ELectron-electron DOuble Resonance) spin technology enabling us to manipulate electron spin-qubits are described.

  4. (55)Mn pulsed ENDOR spectroscopy of Mn(2+) ions in ZnO thin films and single crystal.

    Science.gov (United States)

    Böttcher, Rolf; Pöppl, Andreas; Lorenz, Michael; Friedländer, Stefan; Spemann, Daniel; Grundmann, Marius

    2014-08-01

    (55)Mn pulsed electron nuclear double resonance (ENDOR) experiments were performed at X-band on high spin S=5/2 Mn(2+) ions incorporated at zinc lattice sites in heteroepitaxial ZnO thin films. The films have been prepared by pulsed laser deposition and the manganese ions were doped during the growth process. We examine how the c/a lattice axes ratio of the ZnO films influences the (55)Mn hyperfine (hf) and nuclear quadrupole (nq) coupling parameters of the Mn(2+) probe ions. The results are compared with those obtained for Mn(2+) ions present as impurities in ZnO single crystals and revealed that the (55)Mn nq coupling monitors sensitively the structural distortions in the bonding environment of the Mn(2+) ions. The experiments provided the full axially symmetric (55)Mn hf and nq interaction tensors. The latter is found to be very sensitive to small axial distortions of the MnO4 tetrahedrons. In particular, the (55)Mn pulsed ENDOR spectra of the ZnO:Mn thin films are strongly subjected to strain effects in the nq coupling parameter indicating a variation of the local structural parameters for the heteroepitaxial films. In the analysis of the (55)Mn pulsed ENDOR spectra the axial and cubic zero field splitting of the Mn(2+) ions was taken into account and intensity effects in the ENDOR spectra due to the zero field splitting effects were discussed. Copyright © 2014 Elsevier Inc. All rights reserved.

  5. Davies ENDOR revisited: Enhanced sensitivity and nuclear spin relaxation

    OpenAIRE

    Tyryshkin, Alexei M.; Morton, John J. L.; Ardavan, Arzhang; Lyon, S. A.

    2006-01-01

    Over the past 50 years, electron-nuclear double resonance (ENDOR) has become a fairly ubiquitous spectroscopic technique, allowing the study of spin transitions for nuclei which are coupled to electron spins. However, the low spin number sensitivity of the technique continues to pose serious limitations. Here we demonstrate that signal intensity in a pulsed Davies ENDOR experiment depends strongly on the nuclear relaxation time T1n, and can be severely reduced for long T1n. We suggest a devel...

  6. Multicenter, randomized, tandem evaluation of EndoRings colonoscopy - results of the CLEVER study

    NARCIS (Netherlands)

    Dik, Vincent K; Gralnek, Ian M; Segol, Ori; Suissa, Alain; Belderbos, Tim D G; Moons, Leon M G; Segev, Meytal; Domanov, Sveta; Rex, Douglas K; Siersema, Peter D

    2015-01-01

    Background and study aims: Adenoma miss rate during colonoscopy has become a widely acknowledged proxy measure for post-colonoscopy colorectal cancer. Among other reasons, this can happen because of inadequate visualization of the proximal aspects of colonic folds and flexures. EndoRings (EndoAid Lt

  7. Multicenter, randomized, tandem evaluation of EndoRings colonoscopy - results of the CLEVER study

    NARCIS (Netherlands)

    Dik, V.K.; Gralnek, I.M.; Segol, O.; Suissa, A.; Belderbos, T.D.; Moons, L.M.; Segev, M.; Domanov, S.; Rex, D.K.; Siersema, P.D.

    2015-01-01

    BACKGROUND AND STUDY AIMS: Adenoma miss rate during colonoscopy has become a widely acknowledged proxy measure for post-colonoscopy colorectal cancer. Among other reasons, this can happen because of inadequate visualization of the proximal aspects of colonic folds and flexures. EndoRings (EndoAid Lt

  8. Pulse EPR, 55Mn-ENDOR and ELDOR-detected NMR of the S2-state of the oxygen evolving complex in photosystem II.

    Science.gov (United States)

    Kulik, Leonid; Epel, Boris; Messinger, Johannes; Lubitz, Wolfgang

    2005-06-01

    Pulse EPR, 55Mn-ENDOR and ELDOR-detected NMR experiments were performed on the S2-state of the oxygen-evolving complex from spinach Photosystem II. The novel technique of random acquisition in ENDOR was used to suppress heating artefacts. Our data unambiguously shows that four Mn ions have significant hyperfine coupling constants. Numerical simulation of the 55Mn-ENDOR spectrum allowed the determination of the principal values of the hyperfine interaction tensors for all four Mn ions of the oxygen-evolving complex. The results of our 55Mn-ENDOR experiments are in good agreement with previously published data [Peloquin JM et al. (2000) J Am Chem Soc 122: 10926-10942]. For the first time ELDOR-detected NMR was applied to the S2-state and revealed a broad peak that can be simulated numerically with the same parameters that were used for the simulation of the 55Mn-ENDOR spectrum. This provides strong independent support for the assigned hyperfine parameters.

  9. ENDOR and ELDOR studies of x-irradiated polycrystalline dipeptides, myosin, and actomyosin

    Energy Technology Data Exchange (ETDEWEB)

    Hwang, J.S. (Univ. of Alabama, Tuscaloosa); Dickinson, A.C.; Kispert, L.D.

    1979-12-27

    ENDOR and ELDOR studies have been carried out for nine dipeptide powders as well as powders of myosin and actomyosin x ray irradiated at 77/sup 0/K in an attempt to characterize the final radical stable upon annealing between 183 and 260/sup 0/K. The dipeptides studied were glycylglycine, L-alanylglycine, glycyl-L-alanine, L-alanyl-L-alanine, glycyl-L-aspartic acid, glycyl-L-glutamic acid, glycyl-L-methionine, glycyl-L-serine, and L-lysyl-L-lysine. Nitrogen ENDOR spectra have been observed between 1 and 8 MHz for each powder and the nitrogen hyperfine and quadrupole tensor has been estimated. Analysis of the ENDOR, ELDOR, and ESR spectra indicates at least one of the final radicals in the dipeptide powders (except Gly-Gly, and possibly Gly-Glu, Gly-Ser) to be the decarboxylation product NH/sub 2/CHRCONHCHR' rather than just the abstraction type (NH/sub 3//sup +/-CHRONHCR'COO/sup -/) previously identified in irradiated dipeptide ices. A decarboxylation type radical is also present as a final radical in the irradiated myosin and actomyosin.

  10. Pulsed EPR/ENDOR characterization of perturbations of the Cu(A) center ground state by axial methionine ligand mutations.

    Science.gov (United States)

    Slutter, C E; Gromov, I; Epel, B; Pecht, I; Richards, J H; Goldfarb, D

    2001-06-01

    The effect of axial ligand mutation on the Cu(A) site in the recombinant water soluble fragment of subunit II of Thermus thermophilus cytochrome c oxidase ba(3) has been investigated. The weak methionine ligand was replaced by glutamate and glutamine which are stronger ligands. Two constructs, M160T0 and M160T9, that differ in the length of the peptide were prepared. M160T0 is the original soluble fragment construct of cytochrome ba(3) that encodes 135 amino acids of subunit II, omitting the transmembrane helix that anchors the domain in the membrane. In M160T9 nine C-terminal amino acids are missing, including one histidine. The latter has been used to reduce the amount of a secondary T2 copper which is most probably coordinated to a surface histidine in M160T0. The changes in the spin density in the Cu(A) site, as manifested by the hyperfine couplings of the weakly and strongly coupled nitrogens, and of the cysteine beta-protons, were followed using a combination of advanced EPR techniques. X-band ( approximately 9 GHz) electron-spin-echo envelope modulation (ESEEM) and two-dimensional (2D) hyperfine sublevel correlation (HYSCORE) spectroscopy were employed to measure the weakly coupled (14)N nuclei, and X- and W-band (95 GHz) pulsed electron-nuclear double resonance (ENDOR) spectroscopy for probing the strongly coupled (14)N nuclei and the beta-protons. The high field measurements were extremely useful as they allowed us to resolve the T2 and Cu(A) signals in the g( perpendicular) region and gave (1)H ENDOR spectra free of overlapping (14)N signals. The effects of the M160Q and M160E mutations were: (i) increase in A( parallel)((63,65)Cu), (ii) larger hyperfine coupling of the weakly coupled backbone nitrogen of C153, (iii) reduction in the isotropic hyperfine interaction, a(iso), of some of the beta-protons making them more similar, (iv) the a(iso) value of one of the remote nitrogens of the histidine residues is decreased, thus distinguishing the two

  11. A tunable general purpose Q-band resonator for CW and pulse EPR/ENDOR experiments with large sample access and optical excitation

    Science.gov (United States)

    Reijerse, Edward; Lendzian, Friedhelm; Isaacson, Roger; Lubitz, Wolfgang

    2012-01-01

    We describe a frequency tunable Q-band cavity (34 GHz) designed for CW and pulse Electron Paramagnetic Resonance (EPR) as well as Electron Nuclear Double Resonance (ENDOR) and Electron Electron Double Resonance (ELDOR) experiments. The TE 011 cylindrical resonator is machined either from brass or from graphite (which is subsequently gold plated), to improve the penetration of the 100 kHz field modulation signal. The (self-supporting) ENDOR coil consists of four 0.8 mm silver posts at 2.67 mm distance from the cavity center axis, penetrating through the plunger heads. It is very robust and immune to mechanical vibrations. The coil is electrically shielded to enable CW ENDOR experiments with high RF power (500 W). The top plunger of the cavity is movable and allows a frequency tuning of ±2 GHz. In our setup the standard operation frequency is 34.0 GHz. The microwaves are coupled into the resonator through an iris in the cylinder wall and matching is accomplished by a sliding short in the coupling waveguide. Optical excitation of the sample is enabled through slits in the cavity wall (transmission ˜60%). The resonator accepts 3 mm o.d. sample tubes. This leads to a favorable sensitivity especially for pulse EPR experiments of low concentration biological samples. The probehead dimensions are compatible with that of Bruker flexline Q-band resonators and it fits perfectly into an Oxford CF935 Helium flow cryostat (4-300 K). It is demonstrated that, due to the relatively large active sample volume (20-30 μl), the described resonator has superior concentration sensitivity as compared to commercial pulse Q-band resonators. The quality factor ( Q L) of the resonator can be varied between 2600 (critical coupling) and 1300 (over-coupling). The shortest achieved π/2-pulse durations are 20 ns using a 3 W microwave amplifier. ENDOR (RF) π-pulses of 20 μs ( 1H @ 51 MHz) were obtained for a 300 W amplifier and 7 μs using a 2500 W amplifier. Selected applications of the

  12. Electron-mediating Cu(A) centers in proteins: a comparative high field (1)H ENDOR study.

    Science.gov (United States)

    Epel, Boris; Slutter, Claire S; Neese, Frank; Kroneck, Peter M H; Zumft, Walter G; Pecht, Israel; Farver, Ole; Lu, Yi; Goldfarb, Daniella

    2002-07-10

    High field (W-band, 95 GHz) pulsed electron-nuclear double resonance (ENDOR) measurements were carried out on a number of proteins that contain the mixed-valence, binuclear electron-mediating Cu(A) center. These include nitrous oxide reductase (N(2)OR), the recombinant water-soluble fragment of subunit II of Thermus thermophilus cytochrome c oxidase (COX) ba(3) (M160T9), its M160QT0 mutant, where the weak axial methionine ligand has been replaced by a glutamine, and the engineered "purple" azurin (purpAz). The three-dimensional (3-D) structures of these proteins, apart from the mutant, are known. The EPR spectra of all samples showed the presence of a mononuclear Cu(II) impurity with EPR characteristics of a type II copper. At W-band, the g( perpendicular) features of this center and of Cu(A) are well resolved, thus allowing us to obtain a clean Cu(A) ENDOR spectrum. The latter consists of two types of ENDOR signals. The first includes the signals of the four strongly coupled cysteine beta-protons, with isotropic hyperfine couplings, A(iso), in the 7-15 MHz range. The second group consists of weakly coupled protons with a primarily anisotropic character with A(zz) < 3 MHz. Orientation selective ENDOR spectra were collected for N(2)OR, M160QT0, and purpAz, and simulations of the cysteine beta-protons signals provided their isotropic and anisotropic hyperfine interactions. A linear correlation with a negative slope was found between the maximum A(iso) value of the beta-protons and the copper hyperfine interaction. Comparison of the best-fit anisotropic hyperfine parameters with those calculated from dipolar interactions extracted from the available 3-D structures sets limit to the sulfur spin densities. Similarly, the small coupling spectral region was simulated on the basis of the 3-D structures and compared with the experimental spectra. It was found that the width of the powder patterns of the weakly coupled protons recorded at g(perpendicular) is mainly

  13. EPR, ELDOR, and ENDOR studies of alkali metal- o-dimesitoylbenzene radical complexes in solution. II. The lithium and sodium complexes

    Science.gov (United States)

    van der Drift, E.; Smidt, J.

    A combined EPR-ELDOR-ENDOR study on ion pairs of o-dimesitoylbenzene anions with Li or Na cations provides a unique description of the alkali relaxation pattern in terms of dipolar and quadrupolar relaxation resulting from molecular tumbling. Internal motions in the chelating ring structure appear to be of minor importance. From the EPR and ELDOR results a variety of structural information is obtained: spectral densities, rotational correlation time of the complex, and anisotropic magnetic interactions of the alkali nucleus.

  14. Electronic Structure of ZnO Quantum Dots studied by High-frequency EPR, ESE, ENDOR and ODMR Spectroscopy

    NARCIS (Netherlands)

    Baranov, P.G.; Romanov, N.G.; Bundakova, A.P.; de Mello-Donega, Celso; Schmidt, J.

    2016-01-01

    High-frequency electron paramagnetic resonance (EPR), electron spin echo (ESE), electron-nuclear double resonance (ENDOR) and optically detected magnetic resonance (ODMR) were applied for the investigation of the electronic properties of ZnO colloidal quantum dots (QDs) which consist of a ZnO

  15. Electronic Structure of ZnO Quantum Dots studied by High-frequency EPR, ESE, ENDOR and ODMR Spectroscopy

    NARCIS (Netherlands)

    Baranov, P.G.; Romanov, N.G.; Bundakova, A.P.; de Mello-Donega, Celso; Schmidt, J.

    2016-01-01

    High-frequency electron paramagnetic resonance (EPR), electron spin echo (ESE), electron-nuclear double resonance (ENDOR) and optically detected magnetic resonance (ODMR) were applied for the investigation of the electronic properties of ZnO colloidal quantum dots (QDs) which consist of a ZnO nanocr

  16. Proton Matrix ENDOR Studies on Ca2+-depleted and Sr2+-substituted Manganese Cluster in Photosystem II*

    Science.gov (United States)

    Nagashima, Hiroki; Nakajima, Yoshiki; Shen, Jian-Ren; Mino, Hiroyuki

    2015-01-01

    Proton matrix ENDOR spectra were measured for Ca2+-depleted and Sr2+-substituted photosystem II (PSII) membrane samples from spinach and core complexes from Thermosynechococcus vulcanus in the S2 state. The ENDOR spectra obtained were similar for untreated PSII from T. vulcanus and spinach, as well as for Ca2+-containing and Sr2+-substituted PSII, indicating that the proton arrangements around the manganese cluster in cyanobacterial and higher plant PSII and Ca2+-containing and Sr2+-substituted PSII are similar in the S2 state, in agreement with the similarity of the crystal structure of both Ca2+-containing and Sr2+-substituted PSII in the S1 state. Nevertheless, slightly different hyperfine separations were found between Ca2+-containing and Sr2+-substituted PSII because of modifications of the water protons ligating to the Sr2+ ion. Importantly, Ca2+ depletion caused the loss of ENDOR signals with a 1.36-MHz separation because of the loss of the water proton W4 connecting Ca2+ and YZ directly. With respect to the crystal structure and the functions of Ca2+ in oxygen evolution, it was concluded that the roles of Ca2+ and Sr2+ involve the maintenance of the hydrogen bond network near the Ca2+ site and electron transfer pathway to the manganese cluster. PMID:26438823

  17. Endor Studies of Radiation-Produced Trapped Electrons and Radicals in Disordered Systems and Radical-Matrix Interactions in Polymers and on Surfaces.

    Science.gov (United States)

    1982-04-30

    electron. 8 4. ENDOR and ELDOR of Paramagnetic Species in Disordered Matrices, L. Kevan and P.A. Narayana, Chapter IV, in Multiple Electron Resonance...electron-electron double resonance ( ELDOR ) to radicals trapped in disordered matrices such as glasses and polycrystals are dis- cussed. In...model is currently being developed which appears to give a more quantitative picture of the matrix ENDOR response. ELDOR has been used to evaluate the

  18. The strength of EPR and ENDOR techniques in revealing structure-function relationships in metalloproteins.

    Science.gov (United States)

    Van Doorslaer, Sabine; Vinck, Evi

    2007-09-01

    Recent technological and methodological advances have strongly increased the potential of electron paramagnetic resonance (EPR) and electron nuclear double resonance (ENDOR) techniques to characterize the structure and dynamics of metalloproteins. These developments include the introduction of powerful pulsed EPR/ENDOR methodologies and the development of spectrometers operating at very high microwave frequencies and high magnetic fields. This overview focuses on how valuable information about metalloprotein structure-function relations can be obtained using a combination of EPR and ENDOR techniques. After an overview of the historical development and a limited theoretical description of some of the key EPR and ENDOR techniques, their potential will be highlighted using selected examples of applications to iron-, nickel-, cobalt-, and copper-containing proteins. We will end with an outlook of future developments.

  19. Endor, triple resonance and electron spin echo envelope modulation of 14N in sulphur and selenium coordinated copper(II) complexes

    Science.gov (United States)

    Böttcher, R.; Kirmse, R.; Stach, J.; Reijerse, E. J.; Keijzers, C. P.

    1986-08-01

    Single-crystal ENDOR and TRIPLE resonance studies on "long-range" coupled 14N nuclei are reported for Cu(II) complexes in four host lattices: bis(diethyldithiocarbamato)Ni(II) and Zn(II), bis(diethyldiselenocarbamato)Zn(II) and tetra- n-butylammonium(maleonitriledithiolato)(diethyldithiocarbamato)Ni(II). The ENDOR spectra are unusual because the 14N nuclear quadrupole interaction exceeds the hyperfine coupling and the nuclear Zeeman interaction. The spectra are analyzed in detail and correlated with the molecular structures of the host compounds. According to the TRIPLE experiments the 14N hyperfine tensor components are negative. The populations of the nitrogen orbitals are evaluated from the quadrupole coupling tensors. In order to compare these double resonance methods with pulsed techniques, electron spin echo envelope modulation (ESEEM) is applied to a powder of one of the systems.

  20. FID detection of EPR and ENDOR spectra at high microwave frequencies.

    Science.gov (United States)

    Blok, H; Akimoto, I; Milikisyants, S; Gast, P; Groenen, E J J; Schmidt, J

    2009-11-01

    High-frequency pulsed EPR spectroscopy allows FID detection of EPR spectra owing to the short dead time that can be achieved. This FID detection is particularly attractive for EPR and ENDOR spectroscopy of paramagnetic species that exhibit inhomogeneously broadened EPR lines and short dephasing times. Experiments are reported for the metalloprotein azurin at 275 GHz.

  1. FID detection of EPR and ENDOR spectra at high microwave frequencies

    Science.gov (United States)

    Blok, H.; Akimoto, I.; Milikisyants, S.; Gast, P.; Groenen, E. J. J.; Schmidt, J.

    2009-11-01

    High-frequency pulsed EPR spectroscopy allows FID detection of EPR spectra owing to the short dead time that can be achieved. This FID detection is particularly attractive for EPR and ENDOR spectroscopy of paramagnetic species that exhibit inhomogeneously broadened EPR lines and short dephasing times. Experiments are reported for the metalloprotein azurin at 275 GHz.

  2. Sensitivity Enhancement in Field-Modulated CW ENDOR via RF Bandwidth Broadening

    Science.gov (United States)

    Hoffman, B. M.; Derose, V. J.; Ong, J. L.; Davoust, C. E.

    In low-temperature ENDOR studies it is common to modulate the magnetic field at ν mod ˜ 100 kHz and to observe the ENDOR response as a change in the dispersion-mode rapid-passage EPR signal as decoded at ν mod. The sensitivity of this procedure can be increased by incoherently broadening the bandwidth of the applied RF through mixing of the RF carrier signal with a white-noise source of variable bandwidth. This technique has been explored by monitoring the amplitude and width of ENDOR signals as a function of the RF bandwidth and power, in the case of the 57Fe signals from a metalloprotein and 14N, 1H signals from two Cu(II) compounds. The RF band broadening has produced signal enhancements of over threefold. The results are interpreted in terms of a competition between (i) an increase in the number of spin packets excited within the inhomogeneously broadened ENDOR line and () a reduction in the response per packet. Simple analysis leads to equations for the variation in the ENDOR response with incident RF power and bandwidth that are scaled by a saturation RF power and an effective spin-packet width, respectively.

  3. Interaction of Cr3+ with valence and conduction bands in the long persistent phosphor ZnGa2O4:Cr3+, studied by ENDOR spectroscopy

    Science.gov (United States)

    Binet, Laurent; Sharma, Suchinder K.; Gourier, Didier

    2016-09-01

    Cr3+-doped zinc gallate ZnGa2O4 is a red-near infrared (IR) long persistent phosphor that can be excited by orange-red light, in the transparency window of living tissues. With this property, persistent luminescence nanoparticles were recently used for in vivo optical imaging of tumors in mice. In order to understand the origin of the excitability of persistent luminescence by visible light in this material, a Q-band ENDOR investigation of 71/69Ga and 53Cr nuclei was performed in ZnGa2O4:Cr3+ to get information on the interaction of Cr3+ with valence and conduction bands. The positive electron spin density at Ga nuclei revealed a dominant interaction of the 4A2 ground state of Cr3+ with the valence band, and a weaker interaction with the conduction band. The latter may occur only in the excited 2E and 4T2 states of Cr3+. It is proposed that when these two interactions are present, pairs of electrons and holes can be generated from excited Cr3+ in distorted sites undergoing local electric field produced by neighboring defects with opposite charges.

  4. Strong resistance of Arabidopsis thaliana and Raphanus sativus seeds for ionizing radiation as studied by ESR, ENDOR, ESE spectroscopy and germination measurement: Effect of long-lived and super-long-lived radicals

    Science.gov (United States)

    Kumagai, Jun; Katoh, Hiromi; Kumada, Takayuki; Tanaka, Atsushi; Tano, Shigemitsu; Miyazaki, Tetsuo

    2000-01-01

    Resistance of seeds for ionizing radiation effects on Arabidopsis thaliana and Raphanus sativus seeds were investigated by ESR, ENDOR, ESE spectroscopy and germination measurement. Two types of free radicals, such as long-lived (LL) and super-long-lived (SL) radicals, were produced by the γ-irradiation in the seeds. More than 90% of the 1 kGy-irradiated-seeds can germinate probably by decreasing the LL radicals by absorbing water. 10 kGy-irradiated-seeds cannot germinate at all probably due to the existence of significant amounts of the SL radicals even after absorbing water.

  5. Strong resistance of Arabidopsis thaliana and Raphanus sativus seeds for ionizing radiation as studied by ESR, ENDOR, ESE spectroscopy and germination measurement: Effect of long-lived and super-long-lived radicals

    Energy Technology Data Exchange (ETDEWEB)

    Kumagai, Jun E-mail: kumagai@apchem.nagoya-u.ac.jp; Katoh, Hiromi; Kumada, Takayuki; Tanaka, Atsushi; Tano, Shigemitsu; Miyazaki, Tetsuo

    2000-01-01

    Resistance of seeds for ionizing radiation effects on Arabidopsis thaliana and Raphanus sativus seeds were investigated by ESR, ENDOR, ESE spectroscopy and germination measurement. Two types of free radicals, such as long-lived (LL) and super-long-lived (SL) radicals, were produced by the {gamma}-irradiation in the seeds. More than 90% of the 1 kGy-irradiated-seeds can germinate probably by decreasing the LL radicals by absorbing water. 10 kGy-irradiated-seeds cannot germinate at all probably due to the existence of significant amounts of the SL radicals even after absorbing water. (author)

  6. A 140 GHz pulsed EPR/212 MHz NMR spectrometer for DNP studies

    Science.gov (United States)

    Smith, Albert A.; Corzilius, Björn; Bryant, Jeffrey A.; DeRocher, Ronald; Woskov, Paul P.; Temkin, Richard J.; Griffin, Robert G.

    2012-10-01

    We described a versatile spectrometer designed for the study of dynamic nuclear polarization (DNP) at low temperatures and high fields. The instrument functions both as an NMR spectrometer operating at 212 MHz (1H frequency) with DNP capabilities, and as a pulsed-EPR operating at 140 GHz. A coiled TE011 resonator acts as both an NMR coil and microwave resonator, and a double balanced (1H, 13C) radio frequency circuit greatly stabilizes the NMR performance. A new 140 GHz microwave bridge has also been developed, which utilizes a four-phase network and ELDOR channel at 8.75 GHz, that is then multiplied and mixed to obtain 140 GHz microwave pulses with an output power of 120 mW. Nutation frequencies obtained are as follows: 6 MHz on S = 1/2 electron spins, 100 kHz on 1H, and 50 kHz on 13C. We demonstrate basic EPR, ELDOR, ENDOR, and DNP experiments here. Our solid effect DNP results demonstrate an enhancement of 144 and sensitivity gain of 310 using OX063 trityl at 80 K and an enhancement of 157 and maximum sensitivity gain of 234 using Gd-DOTA at 20 K, which is significantly better performance than previously reported at high fields (⩾3 T).

  7. A 140 GHz pulsed EPR/212 MHz NMR spectrometer for DNP studies.

    Science.gov (United States)

    Smith, Albert A; Corzilius, Björn; Bryant, Jeffrey A; DeRocher, Ronald; Woskov, Paul P; Temkin, Richard J; Griffin, Robert G

    2012-10-01

    We described a versatile spectrometer designed for the study of dynamic nuclear polarization (DNP) at low temperatures and high fields. The instrument functions both as an NMR spectrometer operating at 212 MHz ((1)H frequency) with DNP capabilities, and as a pulsed-EPR operating at 140 GHz. A coiled TE(011) resonator acts as both an NMR coil and microwave resonator, and a double balanced ((1)H, (13)C) radio frequency circuit greatly stabilizes the NMR performance. A new 140 GHz microwave bridge has also been developed, which utilizes a four-phase network and ELDOR channel at 8.75 GHz, that is then multiplied and mixed to obtain 140 GHz microwave pulses with an output power of 120 mW. Nutation frequencies obtained are as follows: 6 MHz on S=1/2 electron spins, 100 kHz on (1)H, and 50 kHz on (13)C. We demonstrate basic EPR, ELDOR, ENDOR, and DNP experiments here. Our solid effect DNP results demonstrate an enhancement of 144 and sensitivity gain of 310 using OX063 trityl at 80 K and an enhancement of 157 and maximum sensitivity gain of 234 using Gd-DOTA at 20 K, which is significantly better performance than previously reported at high fields (≥3 T).

  8. EPR dating CO2- sites in tooth enamel apatites by ENDOR and triple resonance.

    Science.gov (United States)

    Vugman, N V; Rossi, A M; Rigby, S E

    1995-05-01

    In this work we combine electron paramagnetic resonance (EPR), high-resolution electron nucleus double resonance (ENDOR) and general triple resonance (GTR) spectroscopies, to study the local environment of the CO2- groups created by ionizing radiation in fossil tooth enamel. We demonstrate that the CO2- groups occupy slightly modified phosphate sites in the hydroxyapatite lattice. In quaternary shark enamel we found these groups to be interacting with water molecules in the apatite channels. The absence of water molecules as first neighbors in mammalian samples indicate, however, that these molecules are not significantly responsible for the stabilization of CO2- dating centers in enamel.

  9. ELDOR detection of ENDOR transitions in irradiated organic crystals

    Energy Technology Data Exchange (ETDEWEB)

    Kispert, L.D.; Chen, T.C.S.; Hill, J.R.; Clough, S.

    1978-09-01

    The electron--electron double resonance (ELDOR) spectra of free radicals in ..gamma..-irradiated 4-methyl-2,6-ditertiarybutylphenol single crystals and a deuterated derivative having all the hydrogen atoms except those of the 4-methyl group replaced by deuterium contain an unusually narrow ELDOR line (p--p=90 kHz) when highly saturating observing conditions, large pump power, and 100 kHz field modulation are used. The narrow ELDOR line corresponds to a flip of a proton spin relative to the sum of the hyperfine and external field. The transition is driven by the two microwave fields acting together and occurs when the difference of two frequencies is equal to the nuclear resonance frequency. It has previously been observed by ENDOR, but the ELDOR measurements have better sensitivity at higher temperatures. This suggests that ELDOR detection of ENDOR transitions may have wide utility in the accurate measurement of hyperfine interaction parameters.

  10. A Study of New Pulse Auscultation System

    Directory of Open Access Journals (Sweden)

    Ying-Yun Chen

    2015-04-01

    Full Text Available This study presents a new type of pulse auscultation system, which uses a condenser microphone to measure pulse sound waves on the wrist, captures the microphone signal for filtering, amplifies the useful signal and outputs it to an oscilloscope in analog form for waveform display and storage and delivers it to a computer to perform a Fast Fourier Transform (FFT and convert the pulse sound waveform into a heartbeat frequency. Furthermore, it also uses an audio signal amplifier to deliver the pulse sound by speaker. The study observed the principles of Traditional Chinese Medicine’s pulsing techniques, where pulse signals at places called “cun”, “guan” and “chi” of the left hand were measured during lifting (100 g, searching (125 g and pressing (150 g actions. Because the system collects the vibration sound caused by the pulse, the sensor itself is not affected by the applied pressure, unlike current pulse piezoelectric sensing instruments, therefore, under any kind of pulsing pressure, it displays pulse changes and waveforms with the same accuracy. We provide an acquired pulse and waveform signal suitable for Chinese Medicine practitioners’ objective pulse diagnosis, thus providing a scientific basis for this Traditional Chinese Medicine practice. This study also presents a novel circuit design using an active filtering method. An operational amplifier with its differential features eliminates the interference from external signals, including the instant high-frequency noise. In addition, the system has the advantages of simple circuitry, cheap cost and high precision.

  11. Theoretical Studies of the Output Pulse with Variation of the Pumping Pulse for RF Excited CO2 Pulsed Waveguide Laser

    Institute of Scientific and Technical Information of China (English)

    A Rauf; ZHOU Wei; XIN Jian-guo

    2006-01-01

    The behavior of a RF-excited waveguide CO2 laser in the pulse regime is studied theoretically. The output pulse evolution is studied by applying three types of pulses namely the square, sine and the triangular ones as the excitation pulses. The frequency dependence behavior of the output pulse is also presented.

  12. Pulsed DEMO design assessment studies

    CERN Document Server

    Todd, T N

    2013-01-01

    Now that ITER is under construction, interest is increasing in the specification and design of the successor machine, a Demonstration Power Plant (DEMO), which in Europe is coordinated by the EFDA Power Plant Physics and Technology programme. This paper summarises the work carried out for EFDA in 2011-2012 on design issues pertinent to a pulsed version of DEMO, intended to be implemented with little or no extrapolation of technology available today. The work was carried out by the Euratom Fusion Associations CCFE, CEA, CRPP, ENEA and KIT, and in addition to a review of recent relevant literature addressed systems code analyses (pulse length vs. size), erosion of plasma facing components, thermomechanical fatigue in the blanket and first wall, a range of energy storage issues, and fatigue life improvements in Nb3Sn CICC superconductors.

  13. Pulsed electron-nuclear-electron triple resonance spectroscopy

    Science.gov (United States)

    Thomann, Hans; Bernardo, Marcelino

    1990-05-01

    A new experimental technique, pulsed electron-nuclear-electron triple resonance spectroscopy, is demonstrated. It is based on a modification of the pulse sequence for electron-nuclear double resonance (ENDOR) in which two EPR and one NMR transition are irradiated. The irradiation of one EPR transition is detected via a second EPR transition. The nuclear hyperfine coupling, which separates these EPR transition frequencies, is the irradiated NMR transition. The major advantages of triple resonance spectroscopy include the ability to resolve overlapping nuclear resonances in the ENDOR spectrum and a more direct quantitative assignment of nuclear hyperfine and quadrupole couplings. The triple resonance experiment is an alternative to the recently proposed method of employing rapid magnetic field jumps between microwave pulses for generating hyperfine selective ENDOR spectra.

  14. Design Study for Pulsed Proton Beam Generation

    Directory of Open Access Journals (Sweden)

    Han-Sung Kim

    2016-02-01

    Full Text Available Fast neutrons with a broad energy spectrum, with which it is possible to evaluate nuclear data for various research fields such as medical applications and the development of fusion reactors, can be generated by irradiating proton beams on target materials such as beryllium. To generate short-pulse proton beam, we adopted a deflector and slit system. In a simple deflector with slit system, most of the proton beam is blocked by the slit, especially when the beam pulse width is short. Therefore, the available beam current is very low, which results in low neutron flux. In this study, we proposed beam modulation using a buncher cavity to increase the available beam current. The ideal field pattern for the buncher cavity is sawtooth. To make the field pattern similar to a sawtooth waveform, a multiharmonic buncher was adopted. The design process for the multiharmonic buncher includes a beam dynamics calculation and three-dimensional electromagnetic simulation. In addition to the system design for pulsed proton generation, a test bench with a microwave ion source is under preparation to test the performance of the system. The design study results concerning the pulsed proton beam generation and the test bench preparation with some preliminary test results are presented in this paper.

  15. Pulse

    Science.gov (United States)

    ... resting for at least 10 minutes. Take the exercise heart rate while you are exercising. ... pulse rate can help determine if the person's heart is pumping. Pulse ... rate gives information about your fitness level and health.

  16. Explosive Nucleosynthesis Study Using Laser Driven γ-ray Pulses

    Directory of Open Access Journals (Sweden)

    Takehito Hayakawa

    2017-03-01

    Full Text Available We propose nuclear experiments using γ-ray pulses provided from high field plasma generated by high peak power laser. These γ-ray pulses have the excellent features of extremely short pulse, high intensity, and continuous energy distribution. These features are suitable for the study of explosive nucleosyntheses in novae and supernovae, such as the γ process and ν process. We discuss how to generate suitable γ-ray pulses and the nuclear astrophysics involved.

  17. Experimental study of rf pulsed heating

    CERN Document Server

    Laurent, L; Nantista, C; Dolgashev, V; Higashi, Y; Aicheler, M; Tantawi, S; Wuensch, W

    2011-01-01

    Cyclic thermal stresses produced by rf pulsed heating can be the limiting factor on the attainable reliable gradients for room temperature linear accelerators. This is especially true for structures that have complicated features for wakefield damping. These limits could be pushed higher by using special types of copper, copper alloys, or other conducting metals in constructing partial or complete accelerator structures. Here we present an experimental study aimed at determining the potential of these materials for tolerating cyclic thermal fatigue due to rf magnetic fields. A special cavity that has no electric field on the surface was employed in these studies. The cavity shape concentrates the magnetic field on one flat surface where the test material is placed. The materials tested in this study have included oxygen free electronic grade copper, copper zirconium, copper chromium, hot isostatically pressed copper, single crystal copper, electroplated copper, Glidcop (R), copper silver, and silver plated co...

  18. Study on equivalent velocity pulse of nearfault ground motions

    Institute of Scientific and Technical Information of China (English)

    李新乐; 朱晞

    2004-01-01

    Near-fault strong ground motions that resulted in serious structural damage are characterized by directivity effect and pulse-type motion. Large-amplitude and long-period pulses are contained in the velocity time-history traces of near-fault pulse-type records. A reasonable model of equivalent velocity pulse is proposed on the basis of the existed models in this paper to simplify the calculation and analysis. Based on the large amount of collected near-fault strong earthquakes records, the parameters describing equivalent velocity pulse model such as pulse period, pulse intensity and number of predominant pulses are studied, and comparison is made with the results obtained by others models. The proposed model is contributive to the seismic design for structures in near-fault areas.

  19. Thermodynamic basis of electron transfer in dihydroorotate dehydrogenase B from Lactococcus lactis: analysis by potentiometry, EPR spectroscopy, and ENDOR spectroscopy.

    Science.gov (United States)

    Mohsen, Al-Walid A; Rigby, Stephen E J; Jensen, Kaj Frank; Munro, Andrew W; Scrutton, Nigel S

    2004-06-01

    Dihydroorotate dehydrogenase B (DHODB) is a complex iron-sulfur flavoprotein that catalyzes the conversion of dihydroorotate to orotate and the reduction of NAD(+). The enzyme is a dimer of heterodimers containing an FMN, an FAD, and a 2Fe-2S center. UV-visible, EPR, and ENDOR spectroscopies have been used to determine the reduction potentials of the flavins and the 2Fe-2S center and to characterize radicals and their interactions. Reductive titration using dithionite indicates a five-electron capacity for DHODB. The midpoint reduction potential of the 2Fe-2S center (-212 +/- 3 mV) was determined from analysis of absorption data at 540 nm, where absorption contributions from the two flavins are small. The midpoint reduction potentials of the oxidized/semiquinone (E(1)) and semiquinone/hydroquinone (E(2)) couples for the FMN (E(1) = -301 +/- 6 mV; E(2) = -252 +/- 8 mV) and FAD (E(1) = -312 +/- 6 mV; E(2) = -297 +/- 5 mV) were determined from analysis of spectral changes at 630 nm. Corresponding values for the midpoint reduction potentials for FMN (E(1) = -298 +/- 4 mV; E(2) = -259 +/- 5 mV) in the isolated catalytic subunit (subunit D, which lacks the 2Fe-2S center and FAD) are consistent with the values determined for the FMN couples in DHODB. During reductive titration of DHODB, small amounts of the neutral blue semiquinone are observed at approximately 630 nm, consistent with the measured midpoint reduction potentials of the flavins. An ENDOR spectrum of substrate-reduced DHODB identifies hyperfine couplings to proton nuclei similar to those recorded for the blue semiquinone of free flavins in aqueous solution, thus confirming the presence of this species in DHODB. Spectral features observed during EPR spectroscopy of dithionite-reduced DHODB are consistent with the midpoint reduction potentials determined using UV-visible spectroscopy and further identify an unusual EPR signal with very small rhombic anisotropy and g values of 2.02, 1.99, and 1.96. This unusual

  20. Study of terahertz pulses at an edge

    Institute of Scientific and Technical Information of China (English)

    Zaijun Xi; Xiaohan Yu; Tiqiao Xiao

    2008-01-01

    The propagation behaviour of terahertz (THz) pulses at an edge is characterized. The phenomenon that the amplitude oscillates periodically in the frequency spectrum is similar to Young's interference, if the absorption effect is neglected. The oscillation cycle is shorter for a thicker sample. THz pulses at anedge are an alyzed by the broadband Huygens-Fresnel diffraction integral. The experimental results are in agreement with the simulation results approximately. The simulation errors are also analyzed.

  1. Exploratory study on new pulse detonation engines

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    The worldwide progress in studies on pulse detonation engines (PDE) is briefly reviewed and some results of our exploratory study on PDE are presented. Analysis of thermodynamic cycle is made and the specific impulse formula is improved. A proof-of-principle experiment of a two-phase PDE is successfully carried out, using poor-detonable liquid C8H16/air mixture with a low-energy system (total spark energy of 50 mJ) and a newly developed one-step detonation initiation method. The measured detonation wave pressure ratio is very close to that of C-J detonation. The effects of length, diameter and detonation frequency on PDE performance are experimentally investigated. For liquid hydrocarbon fuel/air mixture, the PDE operation is successfully realized with an engine length of 1000 mm and detonation frequency up to 36 Hz, which has made an important step toward practical PDE. The developed code can be used for simulating PDE operation processes including deflagration to detonation transition (DDT) phenomenon. The numerical results are in good agreement with the experimental ones.

  2. Systematic study on pulse parameters in fabricating porous silicon-layered structures by pulse electrochemical etching

    Science.gov (United States)

    Ge, J.; Yin, W. J.; Ma, L. L.; Obbard, E.; Ding, X. M.; Hou, X. Y.

    2007-08-01

    Pulse electrochemical etching was used to improve the quality of porous silicon (PS) layers. Although alternative PS layers of different porosities have been realized by this etching technique, there is no systematic study on the influence of different etching pulse parameters on PS during the etching process. We test various combinations of pulse parameters, including duty cycle and duration, in fabricating PS-layered structures. The optical thickness and actual thickness of the PS structures fabricated are investigated by means of reflectance spectroscopy and scanning electron microscopy. It is found that reducing the duty cycle and pulse duration of the pulse can promote the formation of PS layers with a large optical thickness and high refractive index. Meanwhile, the uniformity of PS is also improved. The duty cycle of 1:10-1:20 and pulse duration of 0.1-0.2 ms can result in the best uniformity and smoothness for the highly doped p-Si wafers. We believe that our work could set the foundation for further improvement of pulse electrochemical etching.

  3. Study of potassium DPAL operation in pulsed and CW mode

    Science.gov (United States)

    Zhdanov, Boris V.; Rotondaro, Matthew D.; Schaffer, Michael K.; Knize, Randall J.

    2014-10-01

    This paper presents the results of our experiments on development of the efficient hydrocarbon free Diode Pumped Alkali Laser based on potassium vapor buffered by He gas at 600 Torr. We studied the performance of this laser operating in pulsed mode with pulses up to 5 ms long at different pulse energies and cell temperatures. A slope efficiency of more than 50% was demonstrated with total optical efficiency about 30% for the pump pulses with duration about 30 μs. For the longer pump pulses the DPAL efficiency degraded in time with a characteristic time in the range from 0.5 ms to 4.5 ms depending on the pump pulse energy and cell temperature. The recorded spectrum of the side fluorescence indicates that multi-photon excitation, energy pooling collisions and ionization may be strong candidates for explaining the observed performance degradation.

  4. An ENDOR spectrum of H atoms in solid H{sub 2}

    Energy Technology Data Exchange (ETDEWEB)

    Kumada, Takayuki; Kumagai, J.; Aratono, Yasuyuki; Miyazaki, T. [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Kitagawa, N.; Noda, T.

    1998-10-01

    An ENDOR spectrum of H atoms produced in the {gamma}-rays irradiated solid H{sub 2} was measured at 4.2 K in order to elucidate the structures of the local environment of the H atoms in solid H{sub 2}. We found that the H atoms were not trapped in interstitial sites but in substitutional sites of the solid, and almost all ortho-H{sub 2} molecules at the first nearest sites from the H atoms converted into para-H{sub 2} molecules. This result shows that the ortho-para conversion is induced by electron spins of the H atoms. (author)

  5. Composite pulses for RF phase encoded MRI: A simulation study.

    Science.gov (United States)

    Salajeghe, Somaie; Babyn, Paul; Sarty, Gordon E

    2017-02-01

    In B1 encoded MRI, a realistic non-linear phase RF encoding coil will generate an inhomogeneous B1 field that leads to spatially dependent flip angles. The non-linearity of the B1 phase gradient can be compensated for in the reconstruction, but B1 inhomogeneity remains a problem. The effect of B1 inhomogeneity on tip angles for conventional, B0 encoded MRI, may be minimized using composite pulses. The objective of this study was to explore the feasibility of using composite pulses with non-linear RF phase encoding coils and to identify the most appropriate composite pulse scheme. RF encoded signals were simulated via the Bloch equation for various symmetric, asymmetric and antisymmetric composite pulses. The simulated signals were reconstructed using a constrained least squares method. Root mean square reconstruction errors varied from 6% (for an asymmetric composite pulse) to 9.7% (for an antisymmetric composite pulse). An asymmetric composite pulse scheme created images with fewer artifacts than other composite pulse schemes in inhomogeneous B0 and B1 fields making it the best choice for decreasing the effects of spatially varying flip angles. This is contrary to the conclusion that antisymmetric composite pulses are the best ones to use for spin echo sequences in conventional, B0 encoded, MRI. Crown Copyright © 2016. Published by Elsevier Inc. All rights reserved.

  6. Uses of pulsed electron beam to solid-states studies

    Energy Technology Data Exchange (ETDEWEB)

    Itoh, Noriaki; Nakayama, Takeyoshi; Tanimura, Katsumi; Chong, Taisu; Saidoh, Masahiro

    1982-03-01

    A survey is given on the use of the pulsed electron beams to studies of solid states. Even though main emphasis is placed on the studies carried out at the Faculty of Engineering, Nagoya University, using the Pulsed Electron Facilities installed in 1970, the works carried out at other institutes are also included. Only the studies of crystalline solids with simple structures, such as alkali halides and aromatic hydrocarbons are covered. In the first place several instrumentations which have extended utilities of pulsed-electron beams are presented. Then we discuss the studies of the dynamic of excitons, emphasizing the advantages and disadvantages of the usage of the electron pulses. Then usages of the pulsed-electron beam for the studies of the excited states of the quasi-stable defects are described. Application of the electron pulse for studies of the excitation spectroscopy of the photochemistry is described. The dynamic studies of defects introduced by electron-pulse bombardment is discussed finally. A summary is given, which includes also the possible future experiments.

  7. Study of the Thin Film Pulse Transformer

    Institute of Scientific and Technical Information of China (English)

    LIU Bao-yuan; SHI Yu; WEN Qi-ye

    2005-01-01

    A new thin film pulse transformer for using in ISND and model systems is fabricated by a mask sputtering process. This novel pulse transformer consists of four I-shaped CoZrRe nanometer crystal magnetic-film cores and a Cu thin film coil, deposited on the micro-crystal glass substrate directly. The thickness of thin film core is between 1 and 3 μm, and the area is between 4mm×6 mm and 12mm×6 mm. The coils provide a relatively high induce of 0.8 μm and can be well operated in a frequency range of 0.001~20 MHz.

  8. Photodissociation of Isoxazole and Pyridine Studied Using Chirped Pulse Microwave Spectroscopy in Pulsed Uniform Supersonic Flows

    Science.gov (United States)

    Ariyasingha, Nuwandi M.; Joalland, Baptiste; Mebel, Alexander M.; Suits, Arthur

    2016-06-01

    Chirped - Pulse Fourier-transform microwave spectroscopy in uniform supersonic flows (Chirped- Pulse/Uniform Flow: CPUF) has been applied to study the photodissociation of two atmospherically relevant N containing heterocyclic compounds; pyridine and isoxazole. Products were detected using rotational spectroscopy. HC3N, HCN were observed for pyridine and CH3CN, HCO and HCN were observed for isoxazole and we report the first detection of HNC for both of the systems. Key points in potential energy surface were explored and compared with the experimental observations. Branching ratios were calculated for all the possible channels and will be presented.

  9. Terahertz pulsed imaging study of dental caries

    Science.gov (United States)

    Karagoz, Burcu; Altan, Hakan; Kamburoglu, Kıvanç

    2015-07-01

    Current diagnostic techniques in dentistry rely predominantly on X-rays to monitor dental caries. Terahertz Pulsed Imaging (TPI) has great potential for medical applications since it is a nondestructive imaging method. It does not cause any ionization hazard on biological samples due to low energy of THz radiation. Even though it is strongly absorbed by water which exhibits very unique chemical and physical properties that contribute to strong interaction with THz radiation, teeth can still be investigated in three dimensions. Recent investigations suggest that this method can be used in the early identification of dental diseases and imperfections in the tooth structure without the hazards of using techniques which rely on x-rays. We constructed a continuous wave (CW) and time-domain reflection mode raster scan THz imaging system that enables us to investigate various teeth samples in two or three dimensions. The samples comprised of either slices of individual tooth samples or rows of teeth embedded in wax, and the imaging was done by scanning the sample across the focus of the THz beam. 2D images were generated by acquiring the intensity of the THz radiation at each pixel, while 3D images were generated by collecting the amplitude of the reflected signal at each pixel. After analyzing the measurements in both the spatial and frequency domains, the results suggest that the THz pulse is sensitive to variations in the structure of the samples that suggest that this method can be useful in detecting the presence of caries.

  10. A Study of Pulse by Pulse Microscale Patch Transfer Using Picosecond Laser

    Directory of Open Access Journals (Sweden)

    Yung KL

    2016-09-01

    Full Text Available The shape restoring capability of Ti/Ni has potential to overcome the shrinkage of polymer in mould cavity, which has potential of solving the demoulding problems and helps dimension accuracy in micro/nano injection molding. However, the deposition of Ti/Ni film precisely and securely on specific location of the micro mould cavity present difficulties with conventional deposition methods. In this paper, the use of photonic impact forward transfer method to deposit Ti/Ni film patches on specific locations of a substrate is demonstrate using a picosecond laser. Pulse by pulse deposition control parameters affecting position accuracy and spot size were studied in this paper. It was found that although laser power, and distance between donor films and the substrate all influence the spot sizes of pulse by pulse deposited patches, adjusting spot size by changing laser power is better than changing distance due to separated particles being found around the deposited film patches. Results of this study proved the feasibility of depositing Ti/Ni film patches on specific location using pico-second laser with high position accuracy. The potential of using photonic impact forward transfer as a complementing method to laser powder 3D printing of difficult to process material to produce better surface quality microproducts such as micro moulds for micro-injection molding is tremendous.

  11. Laparoscopic appendicectomy using endo-ring applicator and fallope rings

    Directory of Open Access Journals (Sweden)

    Ali Iyoob

    2009-01-01

    Full Text Available Background/Aim: Wider adoption of laparoscopic appendicectomy (LA is limited by problems in securing the appendiceal base as well as the cost and the duration compared with the open procedure. The objective of this study was to assess the feasibility and efficacy of a new method for securing the appendiceal base in LA, so as to make the entire procedure simpler and cheaper, and hence, more popular. Methods: Twenty-five patients who were candidates for appendicectomy (emergency as well as elective and willing for the laparoscopic procedure were selected for this study. Ports used were 10 mm at the umbilicus, 5 mm at the lower right iliac fossa, and 10 mm at the left iliac fossa. Extremely friable, ruptured, or turgid organs of diameters larger than 8 mm were excluded from the study. The mesoappendix was divided close to the appendix by diathermy. Fallope rings were applied to the appendiceal base using a special ring applicator, and the appendix was divided and extracted through the lumen of the applicator. Results: The procedure was successful in 23 (92% cases, and the mean duration of the procedure was 20 minutes (15-32 minutes. There were no procedural complications seen during a median follow-up of two weeks. The equipment and rings were cheaper when compared with that of the standard methods of securing the base of the appendix. Conclusion: LA using fallope rings is a safe, simple, easy-to-learn, and economically viable method.

  12. Spin-mapping of coal structures with ESE and ENDOR

    Energy Technology Data Exchange (ETDEWEB)

    Belford, R.L.; Clarkson, R.B.

    1990-06-01

    The overall goal of this project is the development of nondestructive techniques for studying the molecular structure of coal by probing the chemical environment of naturally occurring unpaired electrons with a variety of electron magnetic resonance spectroscopies. One exceptionally promising method for investigating molecular structure in complex solids possessing unpaired electrons is Electron Spin Echo Envelope Modulation (ESEEM) spectroscopy. Currently the aim of our S-band ESEEM work is to develop better methods for the interpretation of multifrequency ESEEM data. This problem is extremely difficult, especially for modulation resulting from quadrupolar nuclei (l > 1/2) such as {sup 33}S, {sup 14}N, and {sup 23}Na. We are pursuing two closely related paths toward this goal. One part of this effort is the development of classification system which would make ESEEM spectra more amenable to a preliminary interpretation by visual inspection. This report describes the testing of some of the capabilities of our recently constructed ESE spectrometer by carrying out a detailed investigation of the molecule DPPH, diphenylpicrylhydrazyl, a well-known stable free radical frequently used to test and tune up electron paramagnetic resonance spectrometers, but details of the nitrogen substituents on one of its aromatic rings have been uncertain and, in fact, the focus of a bit of controversy. It therefore made an excellent subject to select for this test. 14 refs., 2 figs.

  13. Spin-mapping of Coal Structures with ESE and ENDOR

    Science.gov (United States)

    Belford, R. L.; Clarkson, R. B.

    1989-12-01

    The broad goals of this project are to determine by nondestructive magnetic resonance methods chemical and physical structural characteristics of organic parts of native and treated coals. In this project period, we have begun to explore a technique which promises to enable us to follow to course of coal cleaning processes with microscopic spatial resolution. For the past five years, our laboratory has worked on extensions of the EPR technique as applied to coal to address these analytical problems. In this report we (1) describe the world's first nuclear magnetic resonance imaging results from an Illinois {number sign}6 coal and (2) transmit a manuscript describing how organic sulfur affect the very-high-frequency EPR spectra of coals. Magnetic resonance imaging (MRI) is a non-destructive technique that has found wide medical application as a means of visualizing the interior of human bodies. We have used MRI techniques to study the diffusion of an organic solvent (DMSO) into the pores of Illinois {number sign}6 coal. Proton MRI images reveal that this solvent at room temperature does not penetrate approximately 30% of the coal volume. Regions of the coal that exclude solvent could be related to inertinite and mineral components. A multi-technique imaging program is contemplated.

  14. Fundamental studies of pulsed laser ablation

    CERN Document Server

    Claeyssens, F

    2001-01-01

    dopant) have resulted in a coherent view of the resulting plume, which exhibits a multi-component structure correlated with different regimes of ablation, which are attributed to ejection from ZnO and ablation from a Zn melt. OES measurements show that the emitting Zn component within the plume accelerates during expansion in vacuum - an observation attributable to the presence of hot, fast electrons in the plume. The same acceleration behaviour is observed in the case of Al atomic emissions resulting from ablation of an Al target in vacuum. Deposition conditions, substrate temperature and background gas pressure were all varied in a quest for optimally aligned, high quality ZnO thin films. Initial ab initio calculations were performed also, to aid in understanding the stability of these c-axis aligned films. The pulsed ultraviolet (lambda = 193, 248 nm) laser ablation of graphite, polycrystalline diamond and ZnO targets has been investigated. Characteristics of the resulting plumes of ablated material have b...

  15. Pulse radiolysis study on several fluoroquinolones

    Energy Technology Data Exchange (ETDEWEB)

    Zhang Peng [Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800 (China); Graduate University of Chinese Academy of Science, Beijing 100049 (China); Yao Side [Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800 (China); Li Haixia; Song Xiyu; Liu Yancheng [Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800 (China); Graduate University of Chinese Academy of Science, Beijing 100049 (China); Wang Wenfeng, E-mail: wangwenfeng@sinap.ac.c [Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800 (China)

    2011-04-15

    Reactions of several fluoroquinolones (FQs), including enoxacin, norfloxacin, and ciprofloxacin, with various reactive species such as e{sub aq}{sup -}, N{sup {center_dot}}{sub 3}, and {sup {center_dot}O}H are investigated by pulse radiolysis techniques. The FQ radical anions formed in the reactions of FQs with e{sub aq}{sup -} could either be protonated or deprotonated, and the absorption of FQ radical anions was located around 370 nm. The absorption of the neutral radicals produced in the protonation, and the radical dianions produced in the deprotonation of FQ radical anions were located in the 500-750 nm region. The FQ radical cations formed in the reactions of FQs with N{sub 3}{sup {center_dot}} showed an absorption band around 360 nm. Due to the strong bleaching below 350 nm, the absorption maxima ({lambda}{sub max}) of FQ radical anions, and the {lambda}{sub max} of FQ radical cations were not confirmed. The absorption of the FQ radical anions and cations was clearly pH dependent. Under neutral conditions, the reaction rate constants of FQs with e{sub aq}{sup -} and {sup {center_dot}O}H, which are diffusion controlled, were determined.

  16. Computer simulation studies of pulsed Doppler signals from vortices

    Institute of Scientific and Technical Information of China (English)

    CHEN Sizhong; WANG Yuanyuan; WANG Weiqi

    2001-01-01

    A computer simulation method for pulsed Doppler signals from vortices was proposed to generate simulated vortex Doppler signals under various given circumstances. The relative waveforms, such as the maximum frequency waveform, the mean frequency waveform and the bandwidth waveform, were obtained using the short time Fourier analysis of those simulated signals. The relations were studied between several spectrum parameters obtained from these waveforms and given simulation conditions, such as the position and the size of the sample volume, the distance between two vortices, the free stream velocity and the maximum tangent velocity of the vortex. The sensitive parameters were found to detect vortices using the pulsed Doppler techniques.

  17. Increasing sensitivity of pulse EPR experiments using echo train detection schemes

    Science.gov (United States)

    Mentink-Vigier, F.; Collauto, A.; Feintuch, A.; Kaminker, I.; Tarle, V.; Goldfarb, D.

    2013-11-01

    Modern pulse EPR experiments are routinely used to study the structural features of paramagnetic centers. They are usually performed at low temperatures, where relaxation times are long and polarization is high, to achieve a sufficient Signal/Noise Ratio (SNR). However, when working with samples whose amount and/or concentration are limited, sensitivity becomes an issue and therefore measurements may require a significant accumulation time, up to 12 h or more. As the detection scheme of practically all pulse EPR sequences is based on the integration of a spin echo - either primary, stimulated or refocused - a considerable increase in SNR can be obtained by replacing the single echo detection scheme by a train of echoes. All these echoes, generated by Carr-Purcell type sequences, are integrated and summed together to improve the SNR. This scheme is commonly used in NMR and here we demonstrate its applicability to a number of frequently used pulse EPR experiments: Echo-Detected EPR, Davies and Mims ENDOR (Electron-Nuclear Double Resonance), DEER (Electron-Electron Double Resonance|) and EDNMR (Electron-Electron Double Resonance (ELDOR)-Detected NMR), which were combined with a Carr-Purcell-Meiboom-Gill (CPMG) type detection scheme at W-band. By collecting the transient signal and integrating a number of refocused echoes, this detection scheme yielded a 1.6-5 folds SNR improvement, depending on the paramagnetic center and the pulse sequence applied. This improvement is achieved while keeping the experimental time constant and it does not introduce signal distortion.

  18. Contamination Study of Micro Pulsed Plasma Thruster

    Science.gov (United States)

    2008-03-01

    Micro propulsion vacuum facility ...................................................... 26 Figure 16. Oil Diffusion pump of the vacuum facility...increasing interest in the so-called micro - and nano -satellites, which are highly maneuverable and have lower cost. These small satellites are aimed to...option to create very small impulse bits for micro - and nano -satellites. Numerous researchers have studied PPTs but µPPTs are a new technology and need a

  19. A study on the pulse height resolution of organic scintillator digitized pulses

    Energy Technology Data Exchange (ETDEWEB)

    Belli, Francesco, E-mail: Francesco.Belli@enea.it [Associazione EURATOM-ENEA sulla Fusione, C.R. Frascati, C.P. 65, Frascati I-00044, Rome (Italy); Esposito, Basilio; Marocco, Daniele; Riva, Marco [Associazione EURATOM-ENEA sulla Fusione, C.R. Frascati, C.P. 65, Frascati I-00044, Rome (Italy)

    2013-10-15

    Highlights: ► The frequency analysis of pulses from a liquid scintillator detector is performed. ► The minimum sampling rate required to avoid PH degradation is determined. ► It is shown that interpolation methods increase the FoM for n/γ discrimination. -- Abstract: Organic scintillator detectors are widely used for neutron spectroscopy in fusion devices due to their good energy resolution and capability of neutron/gamma discrimination. Nowadays, scintillator pulses are commonly recorded by means of digital acquisition systems. These have several advantages, and in particular the possibility of off-line data reprocessing: however, the signal digitization can be a cause of degradation of the pulse height (PH) resolution (and therefore of the energy resolution obtained after pulse height spectra unfolding). In this work, the problem of how pulse digitization may influence the pulse height resolution is investigated. First, through downsampling of digitized scintillator pulses, we determine the minimum sampling rate required to avoid any degradation of the pulse height resolution. Secondly, we find that the application of interpolation methods to the digitized pulses does not affect the pulse height resolution, whereas it increases the figure of merit for neutron/gamma discrimination. These results are relevant to define the specifications for the digital acquisition systems of neutron detectors in present and future fusion devices such as JET and ITER.

  20. Nonlinear scattering in hard tissue studied with ultrashort laser pulses

    Energy Technology Data Exchange (ETDEWEB)

    Eichler, J. [Technische Fachhochschule Berlin, Univ. of Applied Sciences (Germany); Kim, B.M. [Yonsei Univ., Wonjoo, Kangwon-Do (Korea)

    2002-07-01

    The back-scattered spectrum of ultrashort laser pulses (800 nm, 0.2 ps) was studied in human dental and other hard tissues in vitro below the ablation threshold. Frequency doubled radiation (SHG), frequency tripled radiation and two-photon fluorescence were detected. The relative yield for these processes was measured for various pulse energies. The dependence of the SHG signal on probe thickness was determined in forward and back scattering geometry. SHG is sensitive to linear polarization of the incident laser radiation. SHG in human teeth was studied in vitro showing larger signals in dentin than in cementum and enamel. In carious areas no SHG signal could be detected. Possible applications of higher harmonic radiation for diagnostics and microscopy are discussed. (orig.)

  1. A pulse radiolysis study on electron affinity of piperonal

    Institute of Scientific and Technical Information of China (English)

    MA; Jianhua; LIN; Weizhen; WANG; Wenfeng; YAO; Side

    2005-01-01

    The piperonal electron affinity was studied using pulse radiolysis technique. The electron transfer reaction process between piperonal and anthraquinone-2-sulfate was observed in the pH 7 phosphoric acid salt buffer. The transient absorption spectra of electron transfer reaction between piperonal and anthraquinone-2-sulfate were obtained, and the initial proof of the electron transfer between electron donor and acceptor was provided directly. The one-electron reduction potential of piperonal was determined to be -0.457 V.

  2. Redox transformations in peroxidases studied by pulse radiolysis technique

    Energy Technology Data Exchange (ETDEWEB)

    Gebicka, L.; Gebicki, J.L. (Lodz Univ. (Poland))

    1992-01-01

    By means of pulse radiolysis technique, redox processes in two heme enzymes, horseradish peroxidase (HRP) and lactoperoxidase (LPO) have been studied. It has been found that both hydrated electron and hydroxyl radical reduce HRP and LPO to their ferrous forms. The formation of compound III (an oxyform of the heme enzyme) in a two-step reaction of LPO and HRP with superoxide anion has been proposed. (author).

  3. Preliminary Studies on Pulsed Electric Field Breakdown of Lead Azide

    Science.gov (United States)

    1976-10-01

    1/2 OS CO ton NO. S3L TECHNICAL REPORT 4991 PRELIMINARY SUJDfES ON PULSED ELECTRIC FIELD BREAKDOWN OF LEAD AZIDE L AVRAMI M. BUMS D. DOWNS...Introduction Background A. Contact Effects B. Pulsed Electric Field Measurements Experimental A. Contact Effects B. Pulsed Electric Fields Discussion...B. Pulsed Electric Field Measurements The application of pulsed electric fields to lead azide does not exactly simulate the conditions experienced

  4. Theoretical study of pulsed microwave discharge in nitrogen

    Energy Technology Data Exchange (ETDEWEB)

    Bonaventura, Z; Trunec, D; Mesko, M; Vasina, P; Kudrle, V [Department of Physical Electronics, Faculty of Science, Masaryk University, Kotlarska 2, 611 37 Brno (Czech Republic)

    2005-11-15

    A pulsed microwave discharge burning in pure nitrogen was studied theoretically. The time-dependent Boltzmann equation for electrons was solved numerically in multi-term approximation. It was assumed that the discharge was ignited by a 100 kW microwave (f = 9.4 GHz) pulses with 2.5 {mu}s duration; the repetition frequency was 400 Hz. It was shown that the electron distribution function approaches very quickly the steady state distribution function after a change of the amplitude of electric field intensity. The steady state time averaged values of electron mean energy, diffusion and rate coefficients and drift velocity were calculated for different values of electric field intensity. With these values the actual values of electric field intensity from a previous experiment were determined from the measured time dependence of electron concentration. The calculated values were compared with previous experimental results.

  5. Wave Propagation In Plates Studied By Pulsed Hologram Interferometry

    Science.gov (United States)

    Wahlin, Anders; Fallstrom, Karl-Evert; Gustavsson, H.; Molin, Nils-Erik

    1989-07-01

    Isotropic and non-isotropic plates are impacted by a ballistic pendulum. The bending waves that are generated are studied with holographic interferometry using a double pulsed ruby laser as light source. The pulse shape changes with time because of the dispersivity of the waves. Initially the fringe pattern in the isotropic case is cylindrically symmetric and determined from an initial value problem. Later, when the waves have reached the plate rim, in-and outgoing waves gradually develop fringe patterns which in the end will be a combination of eigenmodes of the plate. A solution to the corresponding Kirchhoff plate equation is presented, which in the special case when the impact is modelled as a Dirac-pulse in space and time, is shown to depend only of the distance to the impact point divided by the square root of the time after impact and a parameter containing plate parameters. From the slope of the central deflection material parameters can be determined. Another solution, assuming a finite inpact time, is shown to agree better with experiments. Results from investigations of non-isotropic materials are also presented.

  6. 5 MW pulsed spallation neutron source, Preconceptual design study

    Energy Technology Data Exchange (ETDEWEB)

    1994-06-01

    This report describes a self-consistent base line design for a 5 MW Pulsed Spallation Neutron Source (PSNS). It is intended to establish feasibility of design and as a basis for further expanded and detailed studies. It may also serve as a basis for establishing project cost (30% accuracy) in order to intercompare competing designs for a PSNS not only on the basis of technical feasibility and technical merit but also on the basis of projected total cost. The accelerator design considered here is based on the objective of a pulsed neutron source obtained by means of a pulsed proton beam with average beam power of 5 MW, in {approx} 1 {mu}sec pulses, operating at a repetition rate of 60 Hz. Two target stations are incorporated in the basic facility: one for operation at 10 Hz for long-wavelength instruments, and one operating at 50 Hz for instruments utilizing thermal neutrons. The design approach for the proton accelerator is to use a low energy linear accelerator (at 0.6 GeV), operating at 60 Hz, in tandem with two fast cycling booster synchrotrons (at 3.6 GeV), operating at 30 Hz. It is assumed here that considerations of cost and overall system reliability may favor the present design approach over the alternative approach pursued elsewhere, whereby use is made of a high energy linear accelerator in conjunction with a dc accumulation ring. With the knowledge that this alternative design is under active development, it was deliberately decided to favor here the low energy linac-fast cycling booster approach. Clearly, the present design, as developed here, must be carried to the full conceptual design stage in order to facilitate a meaningful technology and cost comparison with alternative designs.

  7. Laser-driven hydrothermal process studied with excimer laser pulses

    Science.gov (United States)

    Mariella, Raymond; Rubenchik, Alexander; Fong, Erika; Norton, Mary; Hollingsworth, William; Clarkson, James; Johnsen, Howard; Osborn, David L.

    2017-08-01

    Previously, we discovered [Mariella et al., J. Appl. Phys. 114, 014904 (2013)] that modest-fluence/modest-intensity 351-nm laser pulses, with insufficient fluence/intensity to ablate rock, mineral, or concrete samples via surface vaporization, still removed the surface material from water-submerged target samples with confinement of the removed material, and then dispersed at least some of the removed material into the water as a long-lived suspension of nanoparticles. We called this new process, which appears to include the generation of larger colorless particles, "laser-driven hydrothermal processing" (LDHP) [Mariella et al., J. Appl. Phys. 114, 014904 (2013)]. We, now, report that we have studied this process using 248-nm and 193-nm laser light on submerged concrete, quartzite, and obsidian, and, even though light at these wavelengths is more strongly absorbed than at 351 nm, we found that the overall efficiency of LDHP, in terms of the mass of the target removed per Joule of laser-pulse energy, is lower with 248-nm and 193-nm laser pulses than with 351-nm laser pulses. Given that stronger absorption creates higher peak surface temperatures for comparable laser fluence and intensity, it was surprising to observe reduced efficiencies for material removal. We also measured the nascent particle-size distributions that LDHP creates in the submerging water and found that they do not display the long tail towards larger particle sizes that we had observed when there had been a multi-week delay between experiments and the date of measuring the size distributions. This is consistent with transient dissolution of the solid surface, followed by diffusion-limited kinetics of nucleation and growth of particles from the resulting thin layer of supersaturated solution at the sample surface.

  8. Hydrochemical Differentiation of Salinisation Process of the Water in Endoreic Semi-Arid Basin: Case of Rémila Basin, Algeria

    Directory of Open Access Journals (Sweden)

    Houha Belgacem

    2008-01-01

    Full Text Available The aim of this study is to determine and treat a hierarchical basis of the various mechanisms responsible for the space variation of the water quality in a endoreic semi-arid basin. The water chemistry showed a large variability in space and time. The total dissolved solid (TDS in water increases from upstream to downstream due to the effect of the arid climate, but also due to the water-rock interactions and the anthropic polution of surface water. The water chemistry changes progressively from bicarbonate calcic upstream to sulphated and chlorinated calcic in the median zone to chlorinate sodic in the Sebkha. Thermodynamic modelling showed the major role of evaporation in the evolution of the water chemistry. The result indicated calcite precipitation then gypsum precipitation as well as cations exchanges reactions. Statistical approach allowed to arrange processes that responsible for the hydrochemical variability according to their important. The increase of water salinity is due mainly to the aridity process. The differentiation between salty surface water (Sebkha and deeper water (Chott is the second process. The combined of the geochemical and statistical methods allowed to identify the main

  9. Numerical study on pulse trapping in birefringent photonic crystal fibers

    Institute of Scientific and Technical Information of China (English)

    YAO Yan-yan; LI Shu-guang; FU Bo; ZHANG Lei; ZHANG Mei-yan

    2011-01-01

    Using an adaptive split-step Fourier method, the coupled nonlinear Schrodinger equations have been numerically solved in this paper. The nonlinear propagation of an ultrashort optical pulse in the birefringent photonic crystal fibers is investigated numerically. It is found that the phenomenon of pulse trapping occurs when the incident pulse is deviating from the principal axis of the fiber with some angle. Owing to the bireffingence effect, the incident pulse can be regarded as twoorthogonal polarized pulses. The phenomenon of pulse trapping occurs because of the cross phase modulation (XPM) between the two components. As a result, the bandwidth of the supercontinuum (SC) decreases compared with the case that the incident pulse is input along the principal axis. When the polarization direction of the incident pulse is parallel to the fast axis, the bandwidth of the supercontinuum is maximaL

  10. Repetitively Pulsed Electric Laser Acoustic Studies. Volume 1.

    Science.gov (United States)

    1983-09-01

    INGARD ET AL. SEP 83 UNCLASSIFIED APHAL-IR-83-2858-VOL-1 F336i5 86-C 2848 F/ 0/ 8, EEEmohEEEomhiE EohEEmhohEEEEE mhhhmmomhhlm...TR-83-2058, Vol 9, 0 REPETITIVELY PULSED ELECTRIC LASER ACOUSTIC STUDIES Volume I K. U. INGARD , CHARLES F. MCMILLAN uDEPARTMENT OF AERONAUTICS AND...CONTRACT OR GRANT NUMBER(s) K.U. Ingard and Charles F. McMillan F33615.80-C-2040 9. PERFORMING ORGANIZATION NAME AND ADDRESS 10. PROGRAM ELEMENT. PROJECT

  11. One-electron oxidations of ferrocenes: a pulse radiolysis study

    Energy Technology Data Exchange (ETDEWEB)

    Faraggi, Moshe; Weinraub, Dany; Broitman, Federico; DeFelippis, M.R.; Klapper, M.H.

    1988-01-01

    Using the pulse radiolysis technique we have studied the oxidation by various inorganic radicals of four water soluble ferrocene derivatives, hydroxyethyl, dimethylaminomethyl, monocarboxylic acid and dicarboxylic acid. We report the second order rate constants for these reactions, the stabilities and spectral properties of the ferrocinium products, and the electrochemically determined ferrocinium/ferrocene redox potentials. We also present preliminary estimates of tyrosine and tryptophan radical redox potentials obtained with the dicarboxylic acid ferrocene derivative as reference, and we discuss the relationship between redox potential differences and the reactivities of the ferrocenes with the inorganic radicals.

  12. One-electron oxidations of ferrocenes: A pulse radiolysis study

    Science.gov (United States)

    Faraggi, Moshe; Weinraub, Dany; Broitman, Federico; DeFelippis, Michael R.; Klapper, Michael H.

    Using the pulse radiolysis technique we have studied the oxidation by various inorganic radicals of four water soluble ferrocene derivatives, hydroxyethyl, dimethylaminomethyl, monocarboxylic acid and dicarboxylic acid. We report the second order rate constants for these reactions, the stabilities and spectral properties of the ferrocinium products, and the electrochemically determined ferrocinium/ferrocene redox potentials. We also present preliminary estimates of tyrosine and tryptophan radical redox potentials obtained with the dicarboxylic acid ferrocene derivative as reference, and we discuss the relationship between redox potential differences and the reactivities of the ferrocenes with the inorganic radicals.

  13. Identification of Fe3+-Li+ complexes in ZnO by means of high-frequency EPR/ENDOR spectroscopy

    Science.gov (United States)

    Kutin, Yu. S.; Mamin, G. V.; Orlinskii, S. B.

    2013-12-01

    Theoretical prediction of a high Curie temperature in ZnO doped with Mn, Fe, and other transition metals has stimulated the investigation of these materials by many research groups. Although charge-compensated Fe3+ centers in ZnO:Fe have been observed by means of EPR and have been known for decades, conclusions on the chemical nature of these defects are still contradictory. Originally, these centers were treated as Fe3+-Li+ complexes with both ions occupying adjacent cationic sites. Recently, however, the centers were interpreted as a substitutional Fe3+ ion with a vacancy at an adjacent zinc or oxygen site (Fe-VZn or Fe-VO). In order to determine the chemical nature of the impurity associated with Fe3+, electron-nuclear double resonance (ENDOR) spectroscopy was used. ENDOR measurements reveal NMR transitions corresponding to nuclei with g-factor gN = 2.171 and spin I = 3/2. This unambiguously shows presence of Li as a charge compensator and also resolves contradictions with the theoretical prediction of the Fe-VO formation energy. The electric field gradients at the 7Li nuclei (within the Fe3+-Li+ complexes) were estimated to be significantly lower than the gradient at undistorted Zn sites.

  14. Studying the mechanism of micromachining by short pulsed laser

    Science.gov (United States)

    Gadag, Shiva

    economical, because the micromachining rates are much higher than in the case of the ultra-short pulsed lasers. Hence, studying the mechanisms of micromachining by nanosecond pulsed laser of semiconductor silicon, transparent dielectric glass and quartz is undertaken for this research work. Laser drilling of an array of miniaturized micro holes is termed as laser micro via. A study of the effect of laser wavelengths, frequency, and energy of the pulses on the depth and diameter of craters and micro via are carried out using high resolution optical microscopy and a nano via 3D profiler. Analytical equations correlating depth and volume of the crater in terms of the optical absorption coefficient and ratio of peak applied to the threshold fluence for ablation of the silicon are derived. The depth of crater is scaled in terms of optical penetration depth times the ratio of crater diameter to the beam diameter. The shorter UV wavelengths are found to be more suitable for ablation of Si and SiO2 than longer IR wavelengths from the study of the absorption coefficient of Si varying with wavelength. Hence, the UV lasers (266 nm or 355 nm) are used for micromachining of Si and SiO2 involving cutting, cleaning, drilling and dicing, micro-milling and texturing of submicron size vertically oriented silicon wires for photovoltaic applications. The high density vertical wires are useful to grab a greater density of solar energy to generate more environmentally-friendly green power. The laser drilling of micro via can be typically of two types: (1) percussion drilling using a stationary laser beam with single or multiple pulses of the laser or (2) trepanned drilling of micro via by the circular motion of laser. Numerical simulation of dynamic drilling of laser micro via of silicon is performed, using control volume (FV) Fluent code in a Cartesian co-ordinate system. Total enthalpy formulation is used to simulate the phase change taking place during the laser ablation process from melting

  15. Giant pulses from the Crab pulsar: A wide-band study

    NARCIS (Netherlands)

    Karuppusamy, R.; Stappers, B.W.; van Straten, W.

    2010-01-01

    The Crab pulsar is well-known for its anomalous giant radio pulse emission. Past studies have concentrated only on the very bright pulses or were insensitive to the faint end of the giant pulse luminosity distribution. With our new instrumentation offering a large bandwidth and high time resolution

  16. Study on disinfestation of pulses using microwave technique.

    Science.gov (United States)

    Singh, Ranjeet; Singh, K K; Kotwaliwale, N

    2012-08-01

    Mortality of the pulse beetle (Callosobruchus chinensis L.) exposed, continuously, to microwave radiation (2450 MHz) was evaluated as a function of exposure time and percent power level, at adult stages. The microwave exposure time to attain 100% insect mortality at 100 %, 80%, 60%, 40%, and 20% power levels for Chickpea, Pigeon Pea and Green Gram was optimized. Effect of optimized microwave exposure time on viability, germination, cooking and milling characteristics of Chickpea, Pigeon Pea and Green Gram was also evaluated. Adult stage study was characterized by a distinct dose-exposure curve. The mortality curve was following third degree polynomial equation. The seed viability and germination of Chickpea, Pigeon Pea and Green Gram was affected by microwave exposure time and power level. It was observed that as the power level is decreasing the germination and viability of all the pulses are increasing. The effect on cooking and milling characteristics are not affected by microwave exposure time and power level. The insects in the mobile state were observed to move towards the surface from inside the nutrient medium during microwave exposure. They also curled up and in some cases aggregation was observed.

  17. Pulse wave velocity and digital volume pulse as indirect estimators of blood pressure: pilot study on healthy volunteers.

    Science.gov (United States)

    Padilla, Juan M; Berjano, Enrique J; Sáiz, Javier; Rodriguez, Rafael; Fácila, Lorenzo

    2009-09-01

    The purpose of the study was to asses the potential use of pulse wave velocity (PWV) and digital volume pulse (DVP) as estimators of systolic (SBP) and diastolic (DPB) blood pressure. Single and multiple correlation studies were conducted, including biometric parameters and risk factors. Brachial-ankle PWV (baPWV) and DVP signals were obtained from a Pulse Trace PWV and Pulse Trace PCA (pulse contour analysis), respectively. The DVP (obtained by photoplethysmography), allowed stiffness (SI) and reflection indexes (RI) to be derived. The first study on 47 healthy volunteers showed that both SBP and DPB correlated significantly both with baPWV and SI. Multiple regression models of the baPWV and the waist-to-hip ratio (WHR) allowed SBP and DBP to be modeled with r = 0.838 and r = 0.673, respectively. SI results also employed WHR and modeled SBP and DBP with r = 0.852 and r = 0.663, respectively. RI did not correlate either with SBP or DBP. In order to avoid the use of ultrasound techniques to measure PWV, we then developed a custom-built system to measure PWV by photoplethysmography and validated it against the Pulse Trace. With the same equipment we conducted a second pilot study with ten healthy volunteers. The best SBP multiple regression model for SBP achieved r = 0.997 by considering the heart-finger PWV (hfPWV measured between R-wave and index finger), WHR and heart rate. Only WHR was significant in the DBP model. Our findings suggest that the hfPWV photoplethysmography signal could be a reliable estimator of approximate SBP and could be used, for example, to monitor cardiac patients during physical exercise sessions in cardiac rehabilitation.

  18. Studies of solid propellant combustion with pulsed radiography

    Science.gov (United States)

    Godai, T.; Tanemura, T.; Fujiwara, T.; Shimizu, M.

    1987-01-01

    Pulsed radiography was applied to observe solid propellant surface regression during rocket motor operation. Using a 150 KV flash X-ray system manufactured by the Field Emission Corporation and two kinds of film suppliers, images of the propellant surface of a 5 cm diameter end burning rocket motor were recorded on film. The repetition frame rate of 8 pulses per second and the pulse train length of 10 pulses are limited by the capability of the power supply and the heat build up within the X-ray tube, respectively. The experiment demonstrated the effectiveness of pulsed radiography for observing solid propellant surface regression. Measuring the position of burning surface images on film with a microdensitometer, quasi-instantaneous burning rate as a function of pressure and the variation of characteristic velocity with pressure and gas stay time were obtained. Other research items to which pulsed radiography can be applied are also suggested.

  19. Statistical study of the pulse width distribution for radio pulsars

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    Pulse widths of standard pulse profiles for 262 pulsars were measured by using the Urumqi 25 m radio telescope at 1.54 GHz.For the simplest case of circular emission beam,we applied Monte Carlo simulations to the pulse width distribution.Different density functions of magnetic inclination angle α and observer angle ξ were considered.Using Kolmogorov-Smirnov tests,we derived the most probable distribution for α and ξ.

  20. Study of lower ionosphere by pulse cross-modulation method

    Science.gov (United States)

    Chernogor, L. F.

    1985-02-01

    Three installations in the U.S.S.R. use cross-modulation to study the lower ionosphere from the Earth. Soviet work developed in the following directions: (1) simultaneous use of a number of independent methods; (2) use of broadband apparatus operating in the 1 to 6 MHz band; (3) utilization of both stationary and mobile installations; and (4) utilization of high powers (10 to 100 MW per pulse). Theoretical principle, as well as measurement and processing methods are described. Possibilities and errors of the method are considered. Information on the lower portion of the ionosphere, including the C layer can be collected in the daytime as well as the base of the ionosphere at 75 km at night. A better method for systematic studies of the D region is the partial reflections method.

  1. ENDOR Spectroscopy Reveals A Light Induced Movement of the H-Bond from Ser-L223 Upon Forming the Semiquinone (QB−•) in Reaction Centers from Rhodobacter sphaeroides

    Science.gov (United States)

    Paddock, M. L.; Flores, M.; Isaacson, R.; Chang, C.; Abresch, E. C.; Okamura, M.Y.

    2008-01-01

    Proton ENDOR spectroscopy was used to monitor local conformational changes in bacterial reaction centers (RC) associated with the electron transfer reaction DQB → D+•QB−• using mutant RCs capable of photo-reducing QB at cryogenic temperatures. The charge separated state D+•QB−• was studied in mutant RCs formed by either (i) illuminating at low temperature (77K) a sample frozen in the dark (ground state protein conformation) or (ii) illuminating at room temperature prior to and during the freezing (charge separated state protein conformation). The charge recombination rates from the two states differed greatly (>106 fold) as shown previously, indicating a structural change (Paddock et al (2006) Biochemistry 45, 14032 - 14042). ENDOR spectra of QB−• from both samples (35 GHz, 77K) showed three nearly identical sets of hyperfine couplings due to exchangeable protons that were similar to those for QB−• in native RCs indicating that in all RCs, QB−• was located at the proximal position near the metal site. In contrast, one set of H-bond couplings was observed only in the sample frozen under illumination in which the protein can relax prior to freezing. This H-bond was assigned to an interaction between the Ser-L223 hydroxyl and QB−• based on its absence in Ser L223 → Ala mutant RCs. The Ser-L223 hydroxyl H-bond was also observed in the native RCs frozen under illumination. Thus, part of the protein relaxation in response to light induced charge separation involves the formation of an H-bond between the OH group of Ser-L223 and the anionic semiquinone QB−•. This proton movement serves to stabilize the charge separated state and facilitate proton transfer to reduced QB. PMID:17590017

  2. Pulse-radiolysis study of cytochrome c/sub 3/

    Energy Technology Data Exchange (ETDEWEB)

    van Leeuwen, W.; van Dijk, C.; Grande, H.J.; Veeger, C.

    1982-10-02

    Pulse-radiolysis experiments were performed in the presence of methyl viologen and cytochrome c/sub 3/. After the pulse, methyl viologen radicals are formed and the kinetics of these radicals with cytochrome c/sub 3/ are studied. The reaction between cytochrome c/sub 3/ and methyl viologen radicals (MV/sup +/) is diffusion controlled. The ionic strength dependence and the pH-dependence of this reaction were studied. From the ionic strength dependence (at pH 7.8) we found that the net charge of the fully oxidized cytochrome c/sub 3/ molecule was Z = +4.7 +- 0.7. After the pulse an equilibrium is reached for the reaction of MV/sup +/ with cytochrome c/sub 3/. From this equilibrium an apparent midpoint potential can be obtained. The apparent midpoint potential of this multihaem molecule was found to depend on the degree of reduction, ..cap alpha... With the help of the Nernst equation an empirical equation is obtained to describe this dependence of the midpoint potential: E/sub 0/ = -0.250-0.088 x (in V). An estimation is made of the energy of interaction between the haems due to electrostatic interactions (..delta..epsilon < 32 mV) and due to ionic strength effects (-12 mV < ..delta..epsilon < 26 mV). The results suggest that the redox properties of the individual haems in the cytochrome c/sub 3/ molecule are dependent on the degree of reduction of the other haems in the molecule. The reaction of cytochrome c/sub 3/ with MV/sup +/ or with ethanol radicals (EtOHsup(.)) has been compared with the reactions of horse-heart cytochrome c and of metmyoglobin with the same radicals. The reaction of MV/sup +/ or EtOHsup(.) with horse-heart cytochrome c is found to be diffusion controlled; the reactions with metmyoglobin on the other hand are most probably controlled by an activation energy.

  3. CENTER FOR PULSED POWER DRIVEN HIGH ENERGY DENSITY PLASMA STUDIES

    Energy Technology Data Exchange (ETDEWEB)

    Professor Bruce R. Kusse; Professor David A. Hammer

    2007-04-18

    This annual report summarizes the activities of the Cornell Center for Pulsed-Power-Driven High-Energy-Density Plasma Studies, for the 12-month period October 1, 2005-September 30, 2006. This period corresponds to the first year of the two-year extension (awarded in October, 2005) to the original 3-year NNSA/DOE Cooperative Agreement with Cornell, DE-FC03-02NA00057. As such, the period covered in this report also corresponds to the fourth year of the (now) 5-year term of the Cooperative Agreement. The participants, in addition to Cornell University, include Imperial College, London (IC), the University of Nevada, Reno (UNR), the University of Rochester (UR), the Weizmann Institute of Science (WSI), and the P.N. Lebedev Physical Institute (LPI), Moscow. A listing of all faculty, technical staff and students, both graduate and undergraduate, who participated in Center research activities during the year in question is given in Appendix A.

  4. Corrosion processes in quantized semiconductor colloids studied by pulse radiolysis

    Energy Technology Data Exchange (ETDEWEB)

    Nenadovic, M.T.; Nedeljkovic, J.M.; Micic, O.I.

    1987-04-01

    Electron-transfer reactions from different electron donors to PbSe colloids with diameter size less than 5 nm were studied by pulse-radiolysis techniques. Colloidal particles accept electrons from redox couples whose redox potentials are more negative than -0.8 V (vs. NHE). The optical properties of injected electrons show formation of Pb/sup +/ in bulk semiconductor after 1 ms and then reduction to Pb/sup 0/ in a second slower step ca. 10 s after electron injection. This cathodic corrosion process is also the dominant process during illumination of the colloids in the presence of hole scavengers. The photoreductive corrosion can be partially suppressed in the presence of an electron acceptor. Reduction reactions that cannot occur in bulk materials can occur in sufficiently small particles. Other quantized metal selenides show similar behaviour. The largest yield of hydrogen was produced with extremely small ZnSe colloids.

  5. Pulse radiolysis studies on superoxide reductase from Treponema pallidum

    CERN Document Server

    Nivière, V; Fontecave, M; Houée-Levin, C

    2015-01-01

    Superoxide reductases (SORs) are small metalloenzymes, which catalyze reduction of O2*- to H2O2. The reaction of the enzyme from Treponema pallidum with superoxide was studied by pulse radiolysis methods. The first step is an extremely fast bi-molecular reaction of the ferrous center with O2, with a rate constant of 6 x 10 (8) M(-1) s(-1). A first intermediate is formed which is converted to a second one with a slower rate constant of 4800 s(-1). This latter value is 10 times higher than the corresponding one previously reported in the case of SOR from Desulfoarculus baarsii. The reconstituted spectra for the two intermediates are consistent with formation of transient iron-peroxide species.

  6. Pulsed Electromagnetic Field Assisted in vitro Electroporation: A Pilot Study

    Science.gov (United States)

    Novickij, Vitalij; Grainys, Audrius; Lastauskienė, Eglė; Kananavičiūtė, Rūta; Pamedytytė, Dovilė; Kalėdienė, Lilija; Novickij, Jurij; Miklavčič, Damijan

    2016-09-01

    Electroporation is a phenomenon occurring due to exposure of cells to Pulsed Electric Fields (PEF) which leads to increase of membrane permeability. Electroporation is used in medicine, biotechnology, and food processing. Recently, as an alternative to electroporation by PEF, Pulsed ElectroMagnetic Fields (PEMF) application causing similar biological effects was suggested. Since induced electric field in PEMF however is 2–3 magnitudes lower than in PEF electroporation, the membrane permeabilization mechanism remains hypothetical. We have designed pilot experiments where Saccharomyces cerevisiae and Candida lusitaniae cells were subjected to single 100–250 μs electrical pulse of 800 V with and without concomitant delivery of magnetic pulse (3, 6 and 9 T). As expected, after the PEF pulses only the number of Propidium Iodide (PI) fluorescent cells has increased, indicative of membrane permeabilization. We further show that single sub-millisecond magnetic field pulse did not cause detectable poration of yeast. Concomitant exposure of cells to pulsed electric (PEF) and magnetic field (PMF) however resulted in the increased number PI fluorescent cells and reduced viability. Our results show increased membrane permeability by PEF when combined with magnetic field pulse, which can explain electroporation at considerably lower electric field strengths induced by PEMF compared to classical electroporation.

  7. Studies on Pulse Jet Engine by Wind Tunnel Testing

    OpenAIRE

    Toshihiro Nakano; Michael Zeutzius; Hideo Miyanishi; Toshiaki Setoguchi; Kenji Kaneko

    2001-01-01

    Simple design and efficiency make pulse jet engines attractive for aeronautical short-term operation applications. An active control system extends the operating range and reduces the fuel consumption considerably so that this old technology might gain a new interest. The results on wind tunnel experiments have been reported together with the impact of combustion mode (pulse or steady) on system performance.

  8. Evaluation of temperature–pulse centile charts in identifying serious bacterial illness: observational cohort study

    Science.gov (United States)

    Brent, Andrew J; Lakhanpaul, Monica; Ninis, Nelly; Levin, Michael; MacFaul, Roddy; Thompson, Matthew

    2011-01-01

    Background Distinguishing serious bacterial infection (SBI) from milder/self-limiting infections is often difficult. Interpretation of vital signs is confounded by the effect of temperature on pulse and respiratory rate. Temperature–pulse centile charts have been proposed to improve the predictive value of pulse rate in the clinical assessment of children with suspected SBI. Objectives To assess the utility of proposed temperature–pulse centile charts in the clinical assessment of children with suspected SBI. Study design and participants The predictive value for SBI of temperature–pulse centile categories, pulse centile categories and Advanced Paediatric Life Support (APLS) defined tachycardia were compared among 1360 children aged 3 months to 10 years presenting with suspected infection to a hospital emergency department (ED) in England; and among 325 children who presented to hospitals in the UK with meningococcal disease. Main outcome measure SBI. Results Among children presenting to the ED, 55 (4.0%) had SBI. Pulse centile category, but not temperature–pulse centile category, was strongly associated with risk of SBI (p=0.0005 and 0.288, respectively). APLS defined tachycardia was also strongly associated with SBI (OR 2.90 (95% CI 1.60 to 5.26), p=0.0002). Among children with meningococcal disease, higher pulse and temperature–pulse centile categories were both associated with more severe disease (p=0.004 and 0.041, respectively). Conclusions Increased pulse rate is an important predictor of SBI, supporting National Institute for Health and Clinical Excellence recommendations that pulse rate be routinely measured in the assessment of febrile children. Temperature–pulse centile charts performed more poorly than pulse alone in this study. Further studies are required to evaluate their utility in monitoring the clinical progress of sick children over time. PMID:21233079

  9. Synthesis of silver nanoparticles by laser ablation in ethanol: A pulsed photoacoustic study

    Energy Technology Data Exchange (ETDEWEB)

    Valverde-Alva, M.A., E-mail: azbmiguel@gmail.com [Posgrado en Ciencia e Ingeniería de Materiales, Universidad Nacional Autónoma de México (UNAM), México D.F., C.P. 04510, México (Mexico); García-Fernández, T. [Universidad Autónoma de la Ciudad de México (UACM), Prolongación San Isidro 151, Col. San Lorenzo Tezonco, México D.F., C.P. 09790, México (Mexico); Villagrán-Muniz, M.; Sánchez-Aké, C.; Castañeda-Guzmán, R. [CCADET Universidad Nacional Autónoma de México (UNAM), México D.F., C.P. 04510, México (Mexico); Esparza-Alegría, E. [Facultad de Ciencias, Universidad Nacional Autónoma de México (UNAM), México D.F., C.P. 04510, México (Mexico); Sánchez-Valdés, C.F. [Instituto Potosino de Investigación Científica y Tecnológica A.C., Camino a la Presa San José 2055, Col. Lomas 4a sección, San Luis Potosí, S.L.P., C.P. 78216, México (Mexico); and others

    2015-11-15

    Graphical abstract: - Highlights: • Pulsed photoacoustic technique allowed to determine the production rate of NPs. • Pulsed photoacoustic technique allows to determine the Ag concentration in colloids. • The nanoparticles production rate drops quickly during the first laser pulses. • Nanoparticles production rate is almost constant after few hundreds of laser shots. • Photoacoustic signal amplitude was proportional to fluence on the target surface. - Abstract: The pulsed photoacoustic (PA) technique was used to study the synthesis by laser ablation of silver nanoparticles (Ag-NPs) in ethanol. PA technique allowed to determine the production rate per laser pulse and concentration of synthesized Ag-NPs. The samples were produced by using a pulsed Nd:YAG laser with 1064 nm of wavelength and 7 ns of pulse duration. The laser pulse energy varied from 10 to 100 mJ. Transmission electron microscopy micrographs demonstrated that the obtained nanoparticles were spherical with an average size close to 10 nm. The absorption spectra of the colloids showed a plasmon absorption peak around 400 nm. The PA analyses showed a significant reduction of the production rate of Ag-NPs during the first hundreds of laser pulses. For a higher number of pulses this rate was kept almost constant. Finally, we found that the root mean square (RMS) value of the PA signal was proportional to the laser pulse fluence on the target surface. Thus PA technique was useful to monitor the ablation process.

  10. A spectrograph for studying pulsed infrared laser spectra

    Energy Technology Data Exchange (ETDEWEB)

    Gorlin, G.B.; Filippov, V.N.; Komissarova, I.I.; Ostrobskii, U.I.; Ostrovskaya, G.V.; Paritskii, L.G.; Shevova, E.N.

    1982-01-01

    A spectrograph used to record the pulsed infrared spectra in a wavelength range which exceeds the sensitivity limits of standard photographic materials is described. The spectrograph is built using a standard scheme with mirror optics (f = 60 centimeters) and a diffraction grating 50 lines per millimeter. The recording process involves exposing the photomaterial to a pulsed emission source which is synchronized with a reference infrared emission source created using a purple relief photomaterial. The recording sensitivity is 10exp-2 joules per square centimeter. An interlaced pulsed CO2 laser emission spectrum is derived using the spectrograph.

  11. Theoretical study on pulse-shaping of Stokes pulse with steep leading edge by two Brillouin amplifiers

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    A novel configuration of two Brillouin amplifiers, which contains a main amplifier combined with a reshaping amplifier, is suggested to control pulse shape of Stokes pulses with steep leading edge. Dependences of pulse shapes on several parameters are numerically simulated. By changing the distance between the two amplifiers, the leading edge of amplified pulses can be finely adjusted. Smooth and symmetrical pulses or pulses with slow leading-edge are achieved. Theoretical researches prove that this system is fit for shaping pulses with steep leading edge, especially, for controlling leading edge of pulses. The results provide useful and necessary theoretical basis and guidance for the future experimental research.

  12. A Pulsed Laser and Molecular Beam Apparatus for Surface Studies

    Science.gov (United States)

    1985-03-01

    PRFCAMING ORCANIZATION REPORT NuMSWIS b MONITORING ORGANIZATION RPR :6P" _________ ______._ _ I0 0 1 I &PO*R.TR. o u 1 6NAEOF PERFORMING ORGANIZATION 5.OFFICE...with a second pulsed molecular beam, and the course of the reaction may be followed using several new pulsed surface analysis techniques under...available for electrical and manipulation feedthroughs, roughing and gas inlet lines, as well as special viewports (quartz or MgF 2) for the passage of UV

  13. Studies on Pulse Jet Engine by Wind Tunnel Testing

    Directory of Open Access Journals (Sweden)

    Toshihiro Nakano

    2001-01-01

    Full Text Available Simple design and efficiency make pulse jet engines attractive for aeronautical short-term operation applications. An active control system extends the operating range and reduces the fuel consumption considerably so that this old technology might gain a new interest. The results on wind tunnel experiments have been reported together with the impact of combustion mode (pulse or steady on system performance.

  14. Reactor pulse repeatability studies at the annular core research reactor

    Energy Technology Data Exchange (ETDEWEB)

    DePriest, K.R. [Applied Nuclear Technologies, Sandia National Laboratories, Mail Stop 1146, Post Office Box 5800, Albuquerque, NM 87185-1146 (United States); Trinh, T.Q. [Nuclear Facility Operations, Sandia National Laboratories, Mail Stop 0614, Post Office Box 5800, Albuquerque, NM 87185-1146 (United States); Luker, S. M. [Applied Nuclear Technologies, Sandia National Laboratories, Mail Stop 1146, Post Office Box 5800, Albuquerque, NM 87185-1146 (United States)

    2011-07-01

    The Annular Core Research Reactor (ACRR) at Sandia National Laboratories is a water-moderated pool-type reactor designed for testing many types of objects in the pulse and steady-state mode of operations. Personnel at Sandia began working to improve the repeatability of pulse operations for experimenters in the facility. The ACRR has a unique UO{sub 2}-BeO fuel that makes the task of producing repeatable pulses difficult with the current operating procedure. The ACRR produces a significant quantity of photoneutrons through the {sup 9}Be({gamma}, n){sup 8}Be reaction in the fuel elements. The photoneutrons are the result of the gammas produced during fission and in fission product decay, so their production is very much dependent on the reactor power history and changes throughout the day/week of experiments in the facility. Because the photoneutrons interfere with the delayed-critical measurements required for accurate pulse reactivity prediction, a new operating procedure was created. The photoneutron effects at delayed critical are minimized when using the modified procedure. In addition, the pulse element removal time is standardized for all pulse operations with the modified procedure, and this produces less variation in reactivity removal times. (authors)

  15. Single pulse shock tube study of allyl radical recombination.

    Science.gov (United States)

    Fridlyand, Aleksandr; Lynch, Patrick T; Tranter, Robert S; Brezinsky, Kenneth

    2013-06-13

    The recombination and disproportionation of allyl radicals has been studied in a single pulse shock tube with gas chromatographic measurements at 1-10 bar, 650-1300 K, and 1.4-2 ms reaction times. 1,5-Hexadiene and allyl iodide were used as precursors. Simulation of the results using derived rate expressions from a complementary diaphragmless shock tube/laser schlieren densitometry study provided excellent agreement with precursor consumption and formation of all major stable intermediates. No significant pressure dependence was observed at the present conditions. It was found that under the conditions of these experiments, reactions of allyl radicals in the cooling wave had to be accounted for to accurately simulate the experimental results, and this unusual situation is discussed. In the allyl iodide experiments, higher amounts of allene, propene, and benzene were found at lower temperatures than expected. Possible mechanisms are discussed and suggest that iodine containing species are responsible for the low temperature formation of allene, propene, and benzene.

  16. Pulse Plating on Gold Surfaces Studied by In Situ Scanning Tunneling Microscopy

    DEFF Research Database (Denmark)

    Andersen, Jens Enevold Thaulov; Bech-Nielsen, Gregers; Møller, Per

    1994-01-01

    Deposition of bulk copper on thin film gold surfaces is carried out by computer-aided pulse plating. It is demonstrated that the morphology of the copper deposit can be studied by in situ scanning tunnelling microscopy both in potentiostatic experiments and in galvanostatic experiments. Optimized...... procedures for obtaining smooth deposits by pulse plating are explained in terms of a levelling effect. Possible non-faradaic processes observed in measurements with high frequency pulse plating are discussed....

  17. Pulse Plating on Gold Surfaces Studied by In Situ Scanning Tunneling Microscopy

    DEFF Research Database (Denmark)

    Andersen, Jens Enevold Thaulov; Bech-Nielsen, Gregers; Møller, Per

    1994-01-01

    Deposition of bulk copper on thin film gold surfaces is carried out by computer-aided pulse plating. It is demonstrated that the morphology of the copper deposit can be studied by in situ scanning tunnelling microscopy both in potentiostatic experiments and in galvanostatic experiments. Optimized...... procedures for obtaining smooth deposits by pulse plating are explained in terms of a levelling effect. Possible non-faradaic processes observed in measurements with high frequency pulse plating are discussed....

  18. High-field optically detected EPR and ENDOR of semiconductor defects using W-band microwave Fabry-Pérot resonators.

    Science.gov (United States)

    Spaeth, J-M; Tkach, I; Greulich-Weber, S; Overhof, H

    2005-11-01

    The designs of W-band (approximately 95 GHz) Fabry-Pérot microwave resonators for optically detected EPR and ENDOR using the magnetic circular dichroism of the optical absorption (MCDA) as well as for photo-luminescence-detected EPR are briefly described. We report on the first MCDA-detected high-field EPR/ENDOR investigation of the paramagnetic EL2+ defect in semi-insulating GaAs. The higher-order effects, which prevented the unambiguous analysis of previous MCDA-detected K-band EPR/ENDOR experiments could be suppressed in W-band. The analysis of the ENDOR spectra showed that an extremely precise alignment of the samples is necessary. The paramagnetic El2+ defect turned out to be an As antisite defect, which has four almost equivalent nearest 75As neighbours differing less than 1.5% in the superhyperfine interactions suggestive of an isolated As antisite, while the third 75As shell (fifth neighbour shell) is clearly of lower symmetry than expected for an isolated As antisite. We discuss as a possible solution to this paradoxical situation that EL2+ is an isolated antisite at room temperature, which at low temperature, where all magnetic resonance experiments are performed, associates itself with shallow acceptors such as Zn(Ga)- more than two nearest neighbour distances away. According to recent theoretical calculations, such 'loose' complexes with binding energies between 0.01 eV and 0.05 eV and disturb the equivalence of the nearest neighbour superhyperfine (shf) interactions less than 1.5%. Also, W-band EPR was measured using the photo-luminescence for detection to investigate P dopants in 6H-SiC.

  19. Hydration structure of the Ti(III) cation as revealed by pulse EPR and DFT studies: new insights into a textbook case.

    Science.gov (United States)

    Maurelli, Sara; Livraghi, Stefano; Chiesa, Mario; Giamello, Elio; Van Doorslaer, Sabine; Di Valentin, Cristiana; Pacchioni, Gianfranco

    2011-03-21

    The (17)O and (1)H hyperfine interactions of water ligands in the Ti(III) aquo complex in a frozen solution were determined using Hyperfine Sublevel Correlation (HYSCORE) and Pulse Electron Nuclear Double Resonance (ENDOR) spectroscopies at 9.5 GHz. The isotropic hyperfine interaction (hfi) constant of the water ligand (17)O was found to be about 7.5 MHz. (1)H Single Matched Resonance Transfer (SMART) HYSCORE spectra allowed resolution of the hfi interactions of the two inequivalent water ligand protons and the relative orientations of their hfi tensors. The magnetic and geometrical parameters extracted from the experiments were compared with the results of DFT computations for different geometrical arrangements of the water ligands around the cation. The theoretical observable properties (g tensor (1)H and (17)O hfi tensors and their orientations) of the [Ti(H(2)O)(6)](3+) complex are in quantitative agreement with the experiments for two slightly different geometrical arrangements associated with D(3d) and C(i) symmetries.

  20. Study Pulse Parameters versus Cavity Length for Both Dispersion Regimes in FM Mode Locked

    Directory of Open Access Journals (Sweden)

    Bushra Razooky Mhdi

    2015-03-01

    Full Text Available To demonstrate the effect of changing cavity length for  FM mode locked on pulse parameters and make comparison for both dispersion regime , a plot for each pulse parameter as Lr function are presented for normal and anomalous dispersion regimes. The analysis is based on the theoretical study and the results of numerical simulation using MATLAB. The effect of both normal and anomalous dispersion regimes on output pulses is investigate Fiber length effects on pulse parameters are investigated by driving the modulator into different values. A numerical solution for model equations using fourth-fifth order, Runge-Kutta method is performed through MATLAB 7.0 program. Fiber length effect on pulse parameters is investigated by driving the modulator into different values of lengths. Result shows that, the output pulse width from the FM mode locked equals to τ= 501ns anomalous regime and τ=518ns in normal regime.

  1. Parametric Study of High Frequency Pulse Detonation Tubes

    Science.gov (United States)

    Cutler, Anderw D.

    2008-01-01

    This paper describes development of high frequency pulse detonation tubes similar to a small pulse detonation engine (PDE). A high-speed valve injects a charge of a mixture of fuel and air at rates of up to 1000 Hz into a constant area tube closed at one end. The reactants detonate in the tube and the products exit as a pulsed jet. High frequency pressure transducers are used to monitor the pressure fluctuations in the device and thrust is measured with a balance. The effects of injection frequency, fuel and air flow rates, tube length, and injection location are considered. Both H2 and C2H4 fuels are considered. Optimum (maximum specific thrust) fuel-air compositions and resonant frequencies are identified. Results are compared to PDE calculations. Design rules are postulated and applications to aerodynamic flow control and propulsion are discussed.

  2. Dynamical studies on the generation of periodic surface structures by femtosecond laser pulses

    Directory of Open Access Journals (Sweden)

    Rosenfeld A.

    2013-11-01

    Full Text Available The dynamics of the formation of laser-induced periodic surface structures (LIPSS on fused silica upon irradiation with linearly polarized fs-laser pulses (50 fs pulse duration, 800 nm center wavelength is studied experimentally using a double pulse experiment with cross polarized pulse sequences and a trans illumination femtosecond time-resolved (0.1 ps – 1 ns pump-probe diffraction approach. The results in both experiments confirm the importance of the ultrafast energy deposition and the laser-induced free-electron plasma in the conduction band of the solids for the formation of LIPSS.

  3. Giant pulses from the Crab pulsar: A wide-band study

    CERN Document Server

    Karuppusamy, R; van Straten, W

    2010-01-01

    The Crab pulsar is well-known for its anomalous giant radio pulse emission. Past studies have concentrated only on the very bright pulses or were insensitive to the faint end of the giant pulse luminosity distribution. With our new instrumentation offering a large bandwidth and high time resolution combined with the narrow radio beam of the Westerbork Synthesis Radio Telescope (WSRT), we seek to probe the weak giant pulse emission regime. The WSRT was used in a phased array mode, resolving a large fraction of the Crab nebula. The resulting pulsar signal was recorded using the PuMa II pulsar backend and then coherently dedispersed and searched for giant pulse emission. After careful flux calibration, the data were analysed to study the giant pulse properties. The analysis includes the distributions of the measured pulse widths, intensities, energies, and scattering times. The weak giant pulses are shown to form a separate part of the intensity distribution. The large number of giant pulses detected were used t...

  4. Pulsed radiation studies of carotenoid radicals and excited states

    Energy Technology Data Exchange (ETDEWEB)

    Burke, M

    2001-04-01

    The one-electron reduction potentials of the radical cations of five dietary carotenoids, in aqueous micellar environments, have been obtained from a pulse radiolysis study of electron transfer between the carotenoids and tryptophan radical cations as a function of pH, and lie in the range 980 to 1060 mV. The decays of the carotenoid radical cations suggest a distribution of exponential lifetimes. The radicals persist for up to about one second, depending on the medium and may re-orientate within a biological environment to react with other biomolecules, such as tyrosine, cysteine or ascorbic acid, which was indeed confirmed. Spectral information of carotenoid pigmented liposomes has been collected, subsequently pulse radiolysis was used to generate the radical cations of {beta}-carotene, zeaxanthin and lutein, in unilamellar vesicles of dipalmitoyl phosphatidyl choline. The rate constants for the 'repair' of these carotenoid radical cations by water-soluble vitamin C were found to be similar ({approx}1 x 10{sup 7} M{sup -1}s{sup -1}) for {beta}-carotene and zeaxanthin and somewhat lower ({approx}0.5 x 10{sup 7} M{sup -1}s{sup -1}) for lutein. The results are discussed in terms of the microenvironment of the carotenoids and suggest that for {beta}-carotene, a hydrocarbon carotenoid, the radical cation is able to interact with a water-soluble species even though the parent hydrocarbon carotenoid is probably entirely in the non-polar region of the liposome. Studies investigating the ability of ingested lycopene to protect human lymphoid cells against singlet oxygen and nitrogen dioxide radical mediated cell damage have shown that a high lycopene diet is beneficial in protecting human cells against reactive oxygen species. Triplet states of carotenoids were produced in benzene solvent and their triplet lifetimes were found to depend on the concentration of the parent molecule. The rate constants obtained for ground state quenching correlate with the number

  5. Pulsed Neutron Scattering Studies of Strongly Fluctuating solids, Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Collin Broholm

    2006-06-22

    The conventional description of a solid is based on a static atomic structure with small amplitude so-called harmonic fluctuations about it. This is a final technical report for a project that has explored materials where fluctuations are sufficiently strong to severely challenge this approach and lead to unexpected and potentially useful materials properties. Fluctuations are enhanced when a large number of configurations share the same energy. We used pulsed spallation source neutron scattering to obtain detailed microscopic information about structure and fluctuations in such materials. The results enhance our understanding of strongly fluctuating solids and their potential for technical applications. Because new materials require new experimental techniques, the project has also developed new techniques for probing strongly fluctuating solids. Examples of material that were studied are ZrW2O8 with large amplitude molecular motion that leads to negative thermal expansion, NiGa2S4 where competing interactions lead to an anomalous short range ordered magnet, Pr1- xBixRu2O7 where a partially filled electron shell (Pr) in a weakly disordered environment produces anomalous metallic properties, and TbMnO3 where competing interactions lead to a magneto-electric phase. The experiments on TbMnO3 exemplify the relationship between research funded by this project and future applications. Magneto-electric materials may produce a magnetic field when an electric field is applied or vise versa. Our experiments have clarified the reason why electric and magnetic polarization is coupled in TbMnO3. While this knowledge does not render TbMnO3 useful for applications it will focus the search for a practical room temperature magneto-electric for applications.

  6. Study of pulse mode of processing of the thermoplastic target

    Directory of Open Access Journals (Sweden)

    M. V. Derenovskii

    1983-12-01

    Full Text Available The temperature characteristics and parameters of the relief formation process of thermoplastic target in pulse mode of treatment of target. It was demonstrated the effect on the light transmission characteristics of the material amount of post-erase cycles.

  7. RHEED study of titanium dioxide with pulsed laser deposition

    DEFF Research Database (Denmark)

    Rasmussen, Inge Lise; Pryds, Nini; Schou, Jørgen

    2009-01-01

    Reflection high-energy electron diffraction (RHEED) operated at high pressure has been used to monitor the growth of thin films of titanium dioxide (TiO2) on (1 0 0) magnesium oxide (MgO) substrates by pulsed laser deposition (PLD). The deposition is performed with a synthetic rutile TiO2 target...

  8. STUDY ON PROPERTIES OF PULSE ELECTRODEPOSITED RE-Ni-W-P-SiC COMPOSITE COATINGS

    Institute of Scientific and Technical Information of China (English)

    Z.C. Guo; X.Y. Zhu; R.D. Xu

    2007-01-01

    The effects of pulse frequency f and duty cycle r on the deposition rate, composition, morphology,and hardness of pulse electrodeposited RE (rare earth)-Ni-W-P-SiC composite coatings have been studied. The results indicate that pulse current can improve the deposition rate of RE-Ni-W-P-SiC composite coatings; W, P, and SiC contents in the coating decrease with the increase of pulse frequency and reach the lowest value at f =33Hz, whereas the RE content in the composite coatings increases with the increase of pulse frequency. SiC content decreases with the increase of duty cycle, W content reaches the lowest value, and P content reaches the highest value at r=0.4; pulse current and RE can lend to smaller size of the crystalline grains; however, the effects of different pulse frequency and duty cycle on the morphologies of RE-Ni-W-P-SiC composite coatings are not obvious. The hardness of RE-Ni-W-P-SiC composite coatings is the highest when the duty cycle is at 0.6 and 0.8 and pulse frequency is at 50Hz. At the same pulse frequency, the hardness of RE-Ni-W-P-SiC composite coatings at r=0.8 is higher than that at r=0.6.

  9. EPR and ENDOR Studies of Point Defects in Lithium Tetraborate Crystals

    Science.gov (United States)

    2012-12-14

    these threats has been the rise in terrorism. Terrorist groups, namely al-Qaeda, have shown an ability to be clever and furtive in their plots to attack ...and iridium isotopes since they are widely used for industrial purposes and are easily acquired. These materials could also be used in a dirty bomb

  10. Identification of slow relaxing spin components by pulse EPR techniques in graphene-related materials

    Directory of Open Access Journals (Sweden)

    Antonio Barbon

    2017-01-01

    Full Text Available Electron Paramagnetic Resonance (EPR is a powerful technique that is suitable to study graphene-related materials. The challenging ability requested to the spectroscopy is its capability to resolve the variety of structures, relatively similar, that are obtained in materials produced through different methods, but that also coexist inside a single sample. In general, because of the intrinsic inhomogeneity of the samples, the EPR spectra are therefore a superposition of spectra coming from different structures. We show that by pulse EPR techniques (echo-detected EPR, ESEEM and Mims ENDOR we can identify and characterize species with slow spin relaxing properties. These species are generally called molecular states, and are likely small pieces of graphenic structures of limited dimensions, thus conveniently described by a molecular approach. We have studied commercial reduced graphene oxide and chemically exfoliated graphite, which are characterized by different EPR spectra. Hyperfine spectroscopies enabled us to characterize the molecular components of the different materials, especially in terms of the interaction of the unpaired electrons with protons (number of protons and hyperfine coupling constants. We also obtained useful precious information about extent of delocalization of the molecular states.

  11. Parametric Study of Pulse-Combustor-Driven Ejectors at High-Pressure

    Science.gov (United States)

    Yungster, Shaye; Paxson, Daniel E.; Perkins, Hugh D.

    2015-01-01

    Pulse-combustor configurations developed in recent studies have demonstrated performance levels at high-pressure operating conditions comparable to those observed at atmospheric conditions. However, problems related to the way fuel was being distributed within the pulse combustor were still limiting performance. In the first part of this study, new configurations are investigated computationally aimed at improving the fuel distribution and performance of the pulse-combustor. Subsequent sections investigate the performance of various pulse-combustor driven ejector configurations operating at highpressure conditions, focusing on the effects of fuel equivalence ratio and ejector throat area. The goal is to design pulse-combustor-ejector configurations that maximize pressure gain while achieving a thermal environment acceptable to a turbine, and at the same time maintain acceptable levels of NOx emissions and flow non-uniformities. The computations presented here have demonstrated pressure gains of up to 2.8%.

  12. Central Pulse Pressure in Chronic Kidney Disease: A CRIC Ancillary Study

    Science.gov (United States)

    Townsend, Raymond R.; Chirinos, Julio A.; Parsa, Afshin; Weir, Matthew A.; Sozio, Stephen M.; Lash, James P.; Chen, Jing; Steigerwalt, Susan P.; Go, Alan S.; Hsu, Chi-yuan; Rafey, Mohammed; Wright, Jackson T.; Duckworth, Mark J.; Gadegbeku, Crystal A.; Joffe, Marshall P.

    2010-01-01

    Central pulse pressure can be non-invasively derived using the radial artery tonometric methods. Knowledge of central pressure profiles has predicted cardiovascular morbidity and mortality in several populations of patients, particularly those with known coronary artery disease and those receiving dialysis. Few data exist characterizing central pressure profiles in patients with mild-moderate chronic kidney disease who are not on dialysis. We measured central pulse pressure cross-sectionally in 2531 participants in the Chronic Renal Insufficiency Cohort study to determine correlates of the magnitude of central pulse pressure in the setting of chronic kidney disease. Tertiles of central pulse pressure (CPP) were 51 mmHg with an overall mean (± S.D.) of 46 ± 19 mmHg. Multivariable regression identified the following independent correlates of central pulse pressure: age, gender, diabetes mellitus, heart rate (negatively correlated), glycosylated hemoglobin, hemoglobin, glucose and PTH concentrations. Additional adjustment for brachial mean arterial pressure and brachial pulse pressure showed associations for age, gender, diabetes, weight and heart rate. Discrete intervals of brachial pulse pressure stratification showed substantial overlap within the associated central pulse pressure values. The large size of this unique chronic kidney disease cohort provides an ideal situation to study the role of brachial and central pressure measurements in kidney disease progression and cardiovascular disease incidence. PMID:20660819

  13. EXPERIMENTAL STUDY AND COMPUTATIONAL MODELLING OF GAS FIRED PULSE COMBUSTION

    Directory of Open Access Journals (Sweden)

    I. Smajevic

    2010-06-01

    Full Text Available The paper presents some results of computational modelling of a gas-fired pulse combustor with aerodynamic valves. The development of the model followed experimental investigations during which the combustor geometry and operating conditions were defined. A simple 'tank and tube' approach was adopted by decomposing the combustor into several elements which were modelled separately, together with the interconnecting processes. The solution was obtained by marching integration in time over several cycles. The model reproduced reasonably well the recorded time history and averaged values of all basic parameters and is expected to complement the experiments aiming to develop a pulse combustor as a device for to cleaning the outer sides of power plants’ boiler heating surfaces during operation.

  14. Study on disinfestation of pulses using microwave technique

    OpenAIRE

    Singh, Ranjeet; Singh, K. K.; Kotwaliwale, N.

    2011-01-01

    Mortality of the pulse beetle (Callosobruchus chinensis L.) exposed, continuously, to microwave radiation (2450 MHz) was evaluated as a function of exposure time and percent power level, at adult stages. The microwave exposure time to attain 100% insect mortality at 100 %, 80%, 60%, 40%, and 20% power levels for Chickpea, Pigeon Pea and Green Gram was optimized. Effect of optimized microwave exposure time on viability, germination, cooking and milling characteristics of Chickpea, Pigeon Pea a...

  15. FEASIBILITY STUDY OF PRESSURE PULSING PIPELINE UNPLUGGING TECHNOLOGIES FOR HANFORD

    Energy Technology Data Exchange (ETDEWEB)

    Servin, M. A. [Washington River Protection Solutions, LLC, Richland, WA (United States); Garfield, J. S. [AEM Consulting, LLC (United States); Golcar, G. R. [AEM Consulting, LLC (United States)

    2012-12-20

    The ability to unplug key waste transfer routes is generally essential for successful tank farms operations. All transfer lines run the risk of plugging but the cross site transfer line poses increased risk due to its longer length. The loss of a transfer route needed to support the waste feed delivery mission impacts the cost and schedule of the Hanford clean up mission. This report addresses the engineering feasibility for two pressure pulse technologies, which are similar in concept, for pipeline unplugging.

  16. Study on damage of K9 glass under 248nm ultraviolet pulsed laser irradiation

    Science.gov (United States)

    Wang, Xi; Fang, Xiaodong

    2015-04-01

    The damage of K9 glass under 248nm ultraviolet pulsed laser irradiation was studied. The laser pulse energy was kept within the range of 60mJ to 160mJ, and the repetition rate was adjusted within the range of 1Hz to 40Hz. The damage morphologies of single-pulse and multi-pulse laser irradiation were characterized by optical microscope, and the damage mechanism was discussed. The experimental results indicated that the damage of K9 glass irradiated by 248nm ultraviolet laser mainly followed the thermal-mechanical coupling mechanism and the damage threshold of K9 glass was 2.8J/cm2. The intensity of damage area increased gradually with the increase of the laser pulse number. It was shown that accumulation effect of laser induced damage to K9 glass was obvious.

  17. Pulsed-laser atom probe studies of a precipitation hardened maraging TRIP steel.

    Science.gov (United States)

    Dmitrieva, O; Choi, P; Gerstl, S S A; Ponge, D; Raabe, D

    2011-05-01

    A precipitation hardened maraging TRIP steel was analyzed using a pulsed laser atom probe. The laser pulse energy was varied from 0.3 to 1.9 nJ to study its effect on the measured chemical compositions and spatial resolution. Compositional analyses using proximity histograms did not show any significant variations in the average matrix and precipitate compositions. The only remarkable change in the atom probe data was a decrease in the ++/+ charge state ratios of the elements. The values of the evaporation field used for the reconstructions exhibit a linear dependence on the laser pulse energy. The adjustment of the evaporation fields used in the reconstructions for different laser pulse energies was based on the correlation of the obtained cluster shapes to the TEM observations. No influence of laser pulse energy on chemical composition of the precipitates and on the chemical sharpness of their interfaces was detected. Copyright © 2010 Elsevier B.V. All rights reserved.

  18. High-resolution single-pulse studies of the Vela Pulsar

    CERN Document Server

    Krämer, M; Straten, W

    2002-01-01

    We present high-resolution multi-frequency single-pulse observations of the Vela pulsar, PSR B0833-45, aimed at studying micro-structure, phase-resolved intensity fluctuations and energy distributions at 1.41 and 2.30 GHz. We show that the micro-pulse width in pulsars has a period dependence. Like individual pulses, Vela's micro-pulses are highly elliptically polarized. There is a strong correlation between Stokes parameters V and I in the micro-structure. We show that the V/I distribution is Gaussian with a narrow width and that this width appears to be constant as a function of pulse phase. The phase-resolved intensity distributions of I are best fitted with log-normal statistics. Extra emission components, i.e.``bump'' and ``giant micro-pulses'', discovered by Johnston et al.(2001) are also present at 2.3 GHz. The bump component seems to be an extra component superposed on the main pulse profile but does not appear periodically. The giant micro-pulses are time-resolved and have significant jitter in their ...

  19. Theoretical study of solitonlike propagation of picosecond light pulses interacting with Wannier excitons

    Science.gov (United States)

    Talanina, I.; Burak, D.; Binder, R.; Giessen, H.; Peyghambarian, N.

    1998-07-01

    An analytical and numerical study of light pulse propagation in semiconductors, with pulses spectrally centered at the lowest exciton resonance, is presented. It is shown that, in the limit of negligible phase-space blocking effects, the equation for the excitonic polarization is equivalent to a modified version of the nonlinear Schrödinger equation, for which soliton solutions have been derived by Mihalache et al. [D. Mihalache et al., Phys. Rev. A 47, 3190 (1993)]. The numerical study demonstrates the solitonlike propagation of experimentally relevant input pulses in CdSe crystal and assesses the influence of phase-space blocking effects and dephasing processes.

  20. Pulse radiolysis and spectrophotometric studies on the binding of organic cations with heparin

    Science.gov (United States)

    Jakubowska, Małgorzata; Adamus, Jan; Gębicki, Jerzy; Marcinek, Andrzej; Sikora, Adam

    2014-06-01

    Here we present the spectroscopic and pulse radiolysis studies of the interactions of heparin and some organic cations:methylene blue (MB), 1-methylnicotinamide (MNA+), and its dimer 1,3-bis(1-methylnicotinamide)propane (bis(MNA+)).

  1. Experimental study and mechanism analysis on bioeffects by nanosecond electromagnetic pulses

    Institute of Scientific and Technical Information of China (English)

    王保义; 杨杰斌; 郭庆功; 徐润民; 刘长军; 张弘; 邹方东; 王子淑

    1997-01-01

    The athermal bioeffects caused by nanosecond electromagnetic pulses with body cells was studied by using a broad band transverse EM-wave cell (BTEM CELL). The experimental system and preliminary mechanism analysis were presented.

  2. PULSE: Palomar Ultraviolet Laser for the Study of Exoplanets

    CERN Document Server

    Baranec, Christoph; van Dam, Marcos; Burruss, Rick

    2013-01-01

    PULSE is a new concept to augment the currently operating 5.1-m Hale PALM-3000 exoplanet adaptive optics system with an ultraviolet Rayleigh laser and associated wavefront sensor. By using an ultraviolet laser to measure the high spatial and temporal order turbulence near the telescope aperture, where it dominates, one can extend the faintness limit of natural guide stars needed by PALM-3000. Initial simulations indicate that very-high infrared contrast ratios and good visible-light adaptive optics performance will be achieved by such an upgraded system on stars as faint as mV = 16-17 using an optimized low-order NGS sensor. This will enable direct imaging searches for, and subsequent characterization of, companions around cool, low-mass stars for the first time, as well as routine visible-light imaging twice as sharp as HST for fainter targets. PULSE will reuse the laser and wavefront sensor technologies developed for the automated Robo-AO laser system currently operating at the Palomar 60-inch telescope, as...

  3. Investigation of a pulse compression technique for medical ultrasound: a simulation study.

    Science.gov (United States)

    Rao, N A

    1994-03-01

    Pulse compression techniques that are capable of producing a large signal-to-noise (SNR) enhancement, have been used successfully in many different fields. For medical applications, frequency-dependent attenuation in soft tissue can limit the usefulness of this method. In the paper, this issue is examined through model-simulation studies. Frequency-modulation (FM) chirp, considered in the study, is just one form of pulse coding technique. Pulse propagation effects in soft tissue are modelled as a linear zero phase filter. A method to perform simulations and estimate the effective time-bandwidth product K is outlined. K describes the SNR enhancement attainable under limitations imposed by the soft-tissue medium. An effective time-bandwidth product is evaluated as a function of soft-tissue linear attenuation coefficient alpha o, scatterer depth z and the bandwidth of the interrogating FM pulse, under realistic conditions. Results indicate that, under certain conditions, K can be significantly lower than its expected value in a non-attenuating medium. It is argued that although limitations exist, pulse compression techniques can still be used to improve resolution or increase penetrational depth. The real advantage over conventional short-pulse imaging comes from the possibility that these improvements can be accomplished without increasing the peak intensity of the interrogating pulse above any threshold levels set by possible bio-effect considerations.

  4. Repetitively pulsed electric laser acoustic studies. Volume 1. Final technical report, Jun 80-Jun 83

    Energy Technology Data Exchange (ETDEWEB)

    Ingard, K.U.; McMillan, C.F.

    1983-09-01

    This report summarizes a study of the acoustical characteristics of a closed loop duct system for pulsed lasers with emphasis on acoustic suppression technology. Several topics are considered involving wave propagation reflection and attenuation in a shock tube, in which pulse waves are generated, simulating those in a pulsed laser system. A detailed analysis of the design of parallel-baffle attenuators for suppression of acoustic waves is given, allowing for the contributions of the reflection transmitted and reverberant contributions to the sound pressure field in the optical cavity.

  5. Study of {sup 14}N NQR response to SORC pulse sequence

    Energy Technology Data Exchange (ETDEWEB)

    Konnai, A., E-mail: konnai@nmri.go.jp; Odano, N. [National Maritime Research Institute, Department of Navigation and System Engineering (Japan); Asaji, T. [Nihon University, Department of Chemistry, College of Humanities and Sciences (Japan)

    2008-01-15

    The behavior of nuclear quadrupole resonance (NQR) signals between RF pulses of the strong off-resonance comb (SORC) as well as the spin-locking spin-echo (SLSE) pulse sequences was studied as for {sup 14}N NQR line {nu}{sub +} of dimethylnitramine (CH{sub 3}){sub 2}NNO{sub 2} at 77 K. The periodic variation of the signal amplitude observed by using SORC pulse sequence could be reasonably explained by the theoretical expression reported in the literature.

  6. Studies and research concerning BNFP pilot-scale pulsed columns: column profile and holdup studies

    Energy Technology Data Exchange (ETDEWEB)

    Cermak, A. F.

    1980-11-01

    Experimental studies were conducted on pilot-scaled pulsed columns for the purpose of obtaining data for verification of contactor computer programs. This work is in support of safeguards programs related to determination of near real-time inventories in pulsed columns. Holdup tests were performed resulting in the derivation of an empirical equation for estimation of the dispersed phase holdup in a column. Uranium solvent extraction mass-transfer tests were conducted in which all four process cycles were simulated under coprocessing flowsheet conditions. Extensive data were obtained during these tests on uranium profiles and inventories within the columns. Transient profile data were also determined between selected runs under the tested operating conditions. No concentration peaks could be observed during the transient period. Based on the extensive inventory data taken, empirical equations were developed for relating uranium inventory in a column to the test parameters. These equations were found useful for predicting and estimating the column inventory under the known run conditions.

  7. Pulsed-laser atom probe studies of a precipitation hardened maraging TRIP steel

    Energy Technology Data Exchange (ETDEWEB)

    Dmitrieva, O., E-mail: o.dmitrieva@mpie.de [Max-Planck-Institute for Iron Research, Max-Planck-Str. 1, 40237 Duesseldorf (Germany); Choi, P., E-mail: p.choi@mpie.de [Max-Planck-Institute for Iron Research, Max-Planck-Str. 1, 40237 Duesseldorf (Germany); Gerstl, S.S.A. [Imago Scientific Instruments, Madison, WI 53711 (United States); Ponge, D.; Raabe, D. [Max-Planck-Institute for Iron Research, Max-Planck-Str. 1, 40237 Duesseldorf (Germany)

    2011-05-15

    A precipitation hardened maraging TRIP steel was analyzed using a pulsed laser atom probe. The laser pulse energy was varied from 0.3 to 1.9 nJ to study its effect on the measured chemical compositions and spatial resolution. Compositional analyses using proximity histograms did not show any significant variations in the average matrix and precipitate compositions. The only remarkable change in the atom probe data was a decrease in the ++/+ charge state ratios of the elements. The values of the evaporation field used for the reconstructions exhibit a linear dependence on the laser pulse energy. The adjustment of the evaporation fields used in the reconstructions for different laser pulse energies was based on the correlation of the obtained cluster shapes to the TEM observations. No influence of laser pulse energy on chemical composition of the precipitates and on the chemical sharpness of their interfaces was detected. -- Research highlights: {yields} Changing the laser pulse energy in pulsed-laser atom probe could induce some changes in the analysis results of complex steels. {yields} Decreases in the evaporation fields and the ++/+ charge state ratios were detected with raising laser energy. {yields} Chemical composition of the intermetallic precipitates and the interface sharpness were not influenced by changing the laser energy.

  8. Time resolved studies of H{sub 2}{sup +} dissociation with phase-stabilized laser pulses

    Energy Technology Data Exchange (ETDEWEB)

    Fischer, Bettina

    2010-06-23

    In the course of this thesis, experimental studies on the dissociation of H{sub 2}{sup +}(H{sub 2}{sup +}{yields}p+H) in ultrashort laser pulses with a stabilized carrier-envelope phase (CEP) were carried out. In single-pulse measurements, the ability to control the emission direction of low energetic protons, i.e. the localization of the bound electron at one of the nuclei after dissociation, by the CEP was demonstrated. The coincident detection of the emitted protons and electrons and the measurement of their three-dimensional momentum vectors with a reaction microscope allowed to clarify the localization mechanism. Further control was achieved by a pump-control scheme with two timedelayed CEP-stabilized laser pulses. Here the neutral H{sub 2} molecule was ionized in the first pulse and dissociation was induced by the second pulse. Electron localization was shown to depend on the properties of the bound nuclear wave packet in H{sub 2}{sup +} at the time the control pulse is applied, demonstrating the ability to use the shape and dynamics of the nuclear wave packet as control parameters. Wave packet simulations were performed reproducing qualitatively the experimental results of the single and the two-pulse measurements. For both control schemes, intuitive models are presented, which qualitatively explain the main features of the obtained results. (orig.)

  9. Experimental and numerical study of short pulse effects in FELs

    CERN Document Server

    Khodyachykh, S; Genz, H; Hessler, C; Richter, A; Asgekar, V

    2004-01-01

    We report the experimental and numerical investigations of the influence of short pulse effects occurring in FELs in different operational regimes for electron bunch lengths which are of the order of the slippage distance. Several observables such as the small signal gain, the macropulse power and the spectral distribution of the FEL radiation were determined experimentally within the constraints of the stable focus regime at the infrared FEL at the S- DALINAC and for the limit cycle regime at the Dutch near infrared FEL FELIX. The experimental findings were compared to predictions of numerical simulations based on the 1D time dependent code FEL1D-OSC. The agreement between experiment and simulation is good. Furthermore, the simulations reveal a chaotic behavior of the macropulses for specific values of the slippage as well as period-doubling, two effects that are predicted to show up in the spectral distribution.

  10. Experimental and numerical study of short pulse effects in FELs

    Science.gov (United States)

    Khodyachykh, S.; Brunken, M.; Genz, H.; Hessler, C.; Richter, A.; Asgekar, V.

    2004-09-01

    We report the experimental and numerical investigations of the influence of short pulse effects occurring in FELs in different operational regimes for electron bunch lengths which are of the order of the slippage distance. Several observables such as the small signal gain, the macropulse power and the spectral distribution of the FEL radiation were determined experimentally within the constraints of the stable focus regime at the infrared FEL at the S-DALINAC and for the limit cycle regime at the Dutch near infrared FEL FELIX. The experimental findings were compared to predictions of numerical simulations based on the 1D time dependent code FEL1D-OSC. The agreement between experiment and simulation is good. Furthermore, the simulations reveal a chaotic behavior of the macropulses for specific values of the slippage as well as period-doubling, two effects that are predicted to show up in the spectral distribution.

  11. Analytical study of ultra-short pulse reflectometry

    Energy Technology Data Exchange (ETDEWEB)

    Bruskin, L.G. [Japan Atomic Energy Research Institute, Naka Fusion Research Establishment, Mukoyama, Nakamachi, Naka-gun, Ibaraki-ken (Japan)]. E-mail: bruskinl@fusion.naka.jaeri.go.jp; Mase, A.; Yamamoto, A.; Kogi, Y. [Kyushu University, Advanced Science and Technology Center for Cooperative Research, Fukuoka-ken, Kasuga (Japan)

    2001-10-01

    The results of an analytical treatment of the time-dependent 2D full-wave equation are presented here for the case of ultra-short pulse (USP) reflectometry. We consider several models of the plasma geometry, namely linear and nonlinear slab models, as well as a 2D plasma density profile with cylindrical symmetry. The latter model is more realistic when compared to the 1D stratified plasma models previously employed in all the analytical, and most numerical, treatments, since the plasma in fusion toroidal devices, mirror machines and plasma processing chambers can often be considered axially symmetric on the scale relevant to microwave reflectometry. Based on the results of analytical modelling, a signal record analysis method of profile reconstruction is proposed. The method has the advantage of using raw signal records instead of poorly localized frequency modes, which makes it robust for the profile measurements using USP reflectometry. (author)

  12. Neutronic studies on decoupled hydrogen moderator for a short-pulse spallation source

    Energy Technology Data Exchange (ETDEWEB)

    Harada, Masahide [Neutron Facility Group, Center for Proton Accelerator Facility, Japan Atomic Energy Research Institute, Tokai-mura, Naka-gun, Ibaraki-ken 319-1195 (Japan)]. E-mail: harada@cens.tokai.jaeri.go.jp; Watanabe, Noboru [Neutron Facility Group, Center for Proton Accelerator Facility, Japan Atomic Energy Research Institute, Tokai-mura, Naka-gun, Ibaraki-ken 319-1195 (Japan); Teshigawara, Makoto [Neutron Facility Group, Center for Proton Accelerator Facility, Japan Atomic Energy Research Institute, Tokai-mura, Naka-gun, Ibaraki-ken 319-1195 (Japan); Kai, Tetsuya [Neutron Facility Group, Center for Proton Accelerator Facility, Japan Atomic Energy Research Institute, Tokai-mura, Naka-gun, Ibaraki-ken 319-1195 (Japan); Ikeda, Yujiro [Neutron Facility Group, Center for Proton Accelerator Facility, Japan Atomic Energy Research Institute, Tokai-mura, Naka-gun, Ibaraki-ken 319-1195 (Japan)

    2005-02-21

    Neutronic studies of decoupled hydrogen moderators were performed by calculations taking into account para hydrogen content, decoupling energy, moderator dimensions/shapes and reflector material. Low-energy parts of calculated spectral intensities with different para hydrogen contents were analyzed by a modified Maxwell function to characterize neutron spectra. The result shows that a 100% para hydrogen moderator gives the highest pulse peak intensity together with the narrowest pulse width and the shortest decay times. Pulse broadening with a reflector was explained by time distributions of source neutrons entering into the moderator through a decoupler. Material dependence of time distribution was studied. A decoupling energy higher than 1 eV does not bring about a large improvement in pulse widths and decay times, even at a large penalty in the peak intensity. The optimal moderator thickness was also discussed for a rectangular parallelepipe-shaped and a canteen-shaped moderator.

  13. Spectroscopic studies on diamond like carbon films synthesized by pulsed laser ablation

    Energy Technology Data Exchange (ETDEWEB)

    Panda, Madhusmita; Krishnan, R., E-mail: krish@igcar.gov.in; Ravindran, T. R.; Das, Arindam; Mangamma, G.; Dash, S.; Tyagi, A. K. [Material Science Group, Indira Gandhi Centre for Atomic Research, Kalpakkam - 603102, Tamil Nadu (India)

    2016-05-23

    Hydrogen free Diamond like Carbon (DLC) thin films enriched with C-C sp{sup 3} bonding were grown on Si (111) substrates at laser pulse energies varying from 100 to 400 mJ (DLC-100, DLC-200, DLC-300, DLC-400), by Pulsed Laser Ablation (PLA) utilizing an Nd:YAG laser operating at fundamental wavelength. Structural, optical and morphological evolutions as a function of laser pulse energy were studied by micro Raman, UV-Vis spectroscopic studies and Atomic Force Microscopy (AFM), respectively. Raman spectra analysis provided critical clues for the variation in sp{sup 3} content and optical energy gap. The sp{sup 3} content was estimated using the FWHM of the G peak and found to be in the range of 62-69%. The trend of evolution of sp{sup 3} content matches well with the evolution of I{sub D}/I{sub G} ratio with pulse energy. UV-Vis absorption study of DLC films revealed the variation of optical energy gap with laser pulse energy (1.88 – 2.23 eV), which matches well with the evolution of G-Peak position of the Raman spectra. AFM study revealed that roughness, size and density of particulate in DLC films increase with laser pulse energy.

  14. A numerical solution algorithm and its application to studies of pulsed light fields propagation

    Science.gov (United States)

    Banakh, V. A.; Gerasimova, L. O.; Smalikho, I. N.; Falits, A. V.

    2016-08-01

    A new method for studies of pulsed laser beams propagation in a turbulent atmosphere was proposed. The algorithm of numerical simulation is based on the solution of wave parabolic equation for complex spectral amplitude of wave field using method of splitting into physical factors. Examples of the use of the algorithm in the case the propagation pulsed Laguerre-Gaussian beams of femtosecond duration in the turbulence atmosphere has been shown.

  15. Study of the onset of the acoustic streaming in parallel plate resonators with pulse ultrasound.

    Science.gov (United States)

    Castro, Angelica; Hoyos, Mauricio

    2016-03-01

    In a previous study, we introduced pulse mode ultrasound as a new method for reducing and controlling the acoustic streaming in parallel plate resonators (Hoyos and Castro, 2013). Here, by modifying other parameters such as the resonator geometry and the particle size, we have found a threshold for particle manipulation with ultrasonic standing waves in confined resonators without the influence of the acoustic streaming. We demonstrate that pulse mode ultrasound open the possibility of manipulating particles smaller than 1 μm size.

  16. A Comparative Study of Single-pulse and Double-pulse Laser-Induced Breakdown Spectroscopy with Uranium-containing Samples.

    Science.gov (United States)

    Skrodzki, Patrick J; Becker, Jason R; Diwakar, Prasoon K; Harilal, Sivanandan S; Hassanein, Ahmed

    2016-03-01

    Laser-induced breakdown spectroscopy (LIBS) holds potential advantages in special nuclear material (SNM) sensing and nuclear forensics, which require rapid analysis, minimal sample preparation, and stand-off distance capability. SNM, such as U, however, result in crowded emission spectra with LIBS, and characteristic emission lines are challenging to discern. It is well-known that double-pulse LIBS (DPLIBS) improves the signal intensity for analytes over conventional single-pulse LIBS (SPLIBS). This study investigates the U signal in a glass matrix using DPLIBS and compares it to signal obtained using SPLIBS. Double-pulse LIBS involves sequential firing of a 1.06 µm Nd:YAG pre-pulse and 10.6 µm TEA CO2 heating pulse in a near collinear geometry. Optimization of experimental parameters including inter-pulse delay and energy follows identification of characteristic lines for the bulk analyte Ca and the minor constituent analyte U for both DPLIBS and SPLIBS. Spatial and temporal coupling of the two pulses in the proposed DPLIBS technique yields improvements in analytical merits with a negligible increase in damage to the sample compared to SPLIBS. Subsequently, the study discusses optimum plasma emission conditions of U lines and relative figures of merit in both SPLIBS and DPLIBS. Investigation into plasma characteristics also addresses plausible mechanisms related to the observed U analyte signal variation between SPLIBS and DPLIBS.

  17. Thermodynamic Basis of Electron Transfer in Dihydroorotate Dehydrogenase B from Lactococcus lactis:  Analysis by Potentiometry, EPR Spectroscopy, and ENDOR Spectroscopy

    DEFF Research Database (Denmark)

    Mohnsen, Al-Walid A.; Rigby, Stephen E. J.; Jensen, Kaj Frank

    2004-01-01

    Dihydroorotate dehydrogenase B (DHODB) is a complex iron-sulfur flavoprotein that catalyzes the conversion of dihydroorotate to orotate and the reduction of NAD+. The enzyme is a dimer of heterodimers containing an FMN, an FAD, and a 2Fe-2S center. UV-visible, EPR, and ENDOR spectroscopies have...... similar to those recorded for the blue semiquinone of free flavins in aqueous solution, thus confirming the presence of this species in DHODB. Spectral features observed during EPR spectroscopy of dithionite-reduced DHODB are consistent with the midpoint reduction potentials determined using UV-visible...

  18. Kinematic study of the effect of dispersion in quantum vacuum emission from strong laser pulses

    CERN Document Server

    Finazzi, Stefano

    2012-01-01

    A strong light pulse propagating in a nonlinear medium causes an effective change in the local refractive index. With a suitable tuning of the pulse velocity, the leading and trailing edge of the pulse were predicted to behave as analogue black and white horizons in the limit of a dispersionless medium. In this paper, we study a more realistic situation where the frequency dispersion of the medium is fully taken into account. As soon as negative frequency modes are present in the comoving frame, spontaneous emission of quantum vacuum radiation is expected to arise independently of the presence of horizons. We finally investigate the kinematic constraints put on the emission and we show that the optimal directions to observe Hawking-like emission form a narrow angle with the direction of propagation of the pulse.

  19. Double pulse laser-induced breakdown spectroscopy of explosives: Initial study towards improved discrimination

    Energy Technology Data Exchange (ETDEWEB)

    De Lucia, Frank C. [U.S. Army Research Laboratory, AMSRD-ARL-WM-BD, Aberdeen Proving Ground, MD, 21005-5069 (United States)], E-mail: fdelucia@arl.army.mil; Gottfried, Jennifer L.; Munson, Chase A.; Miziolek, Andrzej W. [U.S. Army Research Laboratory, AMSRD-ARL-WM-BD, Aberdeen Proving Ground, MD, 21005-5069 (United States)

    2007-12-15

    Detecting trace explosive residues at standoff distances in real-time is a difficult problem. One method ideally suited for real-time standoff detection is laser-induced breakdown spectroscopy (LIBS). However, atmospheric oxygen and nitrogen contributes to the LIBS signal from the oxygen- and nitrogen-containing explosive compounds, complicating the discrimination of explosives from other organic materials. While bathing the sample in an inert gas will remove atmospheric oxygen and nitrogen interference, it cannot practically be applied for standoff LIBS. Alternatively, we have investigated the potential of double pulse LIBS to improve the discrimination of explosives by diminishing the contribution of atmospheric oxygen and nitrogen to the LIBS signal. These initial studies compare the close-contact (< 1 m) LIBS spectra of explosives using single pulse LIBS in argon with double pulse LIBS in atmosphere. We have demonstrated improved discrimination of an explosive and an organic interferent using double pulse LIBS to reduce the air entrained in the analytical plasma.

  20. Study on Pulse Skip Modulation Mode in Smart Power Integrated Circuits and Its Test Technology

    Institute of Scientific and Technical Information of China (English)

    LUO Ping

    2005-01-01

    @@ Up to now, the popular control modes for smart power integrated circuit (SPIC) are PWM and PFM.PWM bases on constant frequency variable width (CFVW) control pulse, whereas, PFM bases on constant width variable frequency (CWVF) control pulse. PWM converter has low efficiency with light loads and high amplitude harmonic. On the other hand,the control circuit and filter for PFM are much complex. This dissertation proposes a novel modulation mode named pulse skip modulation (PSM)for SPIC converter, which bases on constant width constant frequency (CWCF) control pulse. It is shown that PSM converter would improve its efficiency and suppress EMI. It also has quick response speed, good interfere rejection and strong robust. Furthermore, it is easy to realize PSM control circuit. The modulating theories of PSM are firstly studied in the world according to the author's investigation.

  1. Psychophysiological Measures of Learning Comfort: Study Groups' Learning Styles and Pulse Changes

    Science.gov (United States)

    Holliday, Tacy L.; Said, Sukhaynah H.

    2008-01-01

    This study provided empirical support for tutor-led study groups using a physiological measurement and study survey data. The scope of this preliminary study included determining differences in biology and chemistry study group members' (N = 25) regarding learning styles and pulse rate changes. As hypothesized, there was significant evidence that…

  2. Inactivation of Pseudomonas putida by pulsed electric field treatment: a study on the correlation of treatment parameters and inactivation efficiency in the short-pulse range.

    Science.gov (United States)

    Frey, Wolfgang; Gusbeth, Christian; Schwartz, Thomas

    2013-10-01

    An important issue for an economic application of the pulsed electric field treatment for bacterial decontamination of wastewater is the specific treatment energy needed for effective reduction of bacterial populations. The present experimental study performed in a field amplitude range of 40 > E > 200 kV/cm and for a suspension conductivity of 0.01 = κ(e) > 0.2 S/m focusses on the application of short pulses, 25 ns > T > 10 μs, of rectangular, bipolar and exponential shape and was made on Pseudomonas putida, which is a typical and widespread wastewater microorganism. The comparison of inactivation results with calculations of the temporal and azimuthal membrane charging dynamics using the model of Pauly and Schwan revealed that for efficient inactivation, membrane segments at the cell equator have to be charged quickly and to a sufficiently high value, on the order of 0.5 V. After fulfilling this basic condition by an appropriate choice of pulse field strength and duration, the log rate of inactivation for a given suspension conductivity of 0.2 S/m was found to be independent of the duration of individual pulses for constant treatment energy expenditure. Moreover, experimental results suggest that even pulse shape plays a minor role in inactivation efficiency. The variation of the suspension conductivity resulted in comparable inactivation performance of identical pulse parameters if the product of pulse duration and number of pulses was the same, i.e., required treatment energy can be linearly downscaled for lower conductivities, provided that pulse amplitude and duration are selected for entire membrane surface permeabilization.

  3. Numerical Study of Pulsed Dielectric Barrier Discharge at Atmospheric Pressure Under the Needle-Plate Electrode Configuration

    Institute of Scientific and Technical Information of China (English)

    WANG Yanhui; YE Huanhuan; ZHANG Jiao; WANG Qi; ZHANG Jie; WANG Dezhen

    2016-01-01

    In this paper,we study the characteristics of atmospheric-pressure pulsed dielectric barrier discharge (DBD) under the needle-plate electrode configuration using a one-dimensional self-consistent fluid model.The results show that,the DBDs driven by positive pulse,negative pulse and bipolar pulse possess different behaviors.Moreover,the two discharges appearing at the rising and the falling phases of per voltage pulse also have different discharge regimes.For the case of the positive pulse,the breakdown field is much lower than that of the negative pulse,and its propagation characteristic is different from the negative pulse DBD.When the DBD is driven by a bipolar pulse voltage,there exists the interaction between the positive and negative pulses,resulting in the decrease of the breakdown field of the negative pulse DBD and causing the change of the discharge behaviors.In addition,the effects of the discharge parameters on the behaviors of pulsed DBD in the needle-plate electrode configuration are also studied.

  4. Numerical modeling of ozone production in a pulsed homogeneous discharge: A parameter study

    Energy Technology Data Exchange (ETDEWEB)

    Nilsson, J.O.; Eninger, J.E. [Royal Inst. of Tech., Stockholm (Sweden). Dept. of Industrial Electrotechnology

    1997-02-01

    The pulsed volume discharge is an alternative for the efficient generation of ozone in compact systems. This paper presents a parameter study of the reactions in this kind of homogeneous discharge by using a numerical model which solves plasma chemical kinetic rate and energy equations. Results are presented of ozone generation efficiency versus ozone concentration for different parameter combinations. Two parameter regimes are identified and analyzed. In the plasma phase ozone formation regime, where significant amounts of ozone are produced during the discharge pulse, it is found that higher ozone concentrations can be obtained than in the neutral phase ozone formation regime, where most of the ozone is formed after the discharge pulse. In the two-step ozone formation process, the rate of conversion of atomic oxygen plays a key role. In both regimes the ozone generation efficiency increases as n is increased or T{sub 0} decreased. The maximum concentration is 3% at 10 amagat and 100 K. The results on ozone accumulation in multiple pulse discharges are presented. In contrast to the single pulse case, higher efficiency is achieved at lower gas density. This scaling can be explained by losses due to ion currents. A tradeoff can be made between ozone generation efficiency and the number of pulses required to reach a certain concentration.

  5. A nanosecond pulsed laser heating system for studying liquid and supercooled liquid films in ultrahigh vacuum

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Yuntao [Physical Sciences Division, Pacific Northwest National Laboratory, P.O. Box 999, Richland, Washington 99352, USA; Dibble, Collin J. [Physical Sciences Division, Pacific Northwest National Laboratory, P.O. Box 999, Richland, Washington 99352, USA; Petrik, Nikolay G. [Physical Sciences Division, Pacific Northwest National Laboratory, P.O. Box 999, Richland, Washington 99352, USA; Smith, R. Scott [Physical Sciences Division, Pacific Northwest National Laboratory, P.O. Box 999, Richland, Washington 99352, USA; Joly, Alan G. [Physical Sciences Division, Pacific Northwest National Laboratory, P.O. Box 999, Richland, Washington 99352, USA; Tonkyn, Russell G. [Physical Sciences Division, Pacific Northwest National Laboratory, P.O. Box 999, Richland, Washington 99352, USA; Kay, Bruce D. [Physical Sciences Division, Pacific Northwest National Laboratory, P.O. Box 999, Richland, Washington 99352, USA; Kimmel, Greg A. [Physical Sciences Division, Pacific Northwest National Laboratory, P.O. Box 999, Richland, Washington 99352, USA

    2016-04-26

    A pulsed laser heating system has been developed that enables investigations of the dynamics and kinetics of nanoscale liquid films and liquid/solid interfaces on the nanosecond timescale in ultrahigh vacuum (UHV). Details of the design, implementation and characterization of a nanosecond pulsed laser system for transiently heating nanoscale films are described. Nanosecond pulses from a Nd:YAG laser are used to rapidly heat thin films of adsorbed water or other volatile materials on a clean, well-characterized Pt(111) crystal in UHV. Heating rates of ~1010 K/s for temperature increases of ~100 – 200 K are obtained. Subsequent rapid cooling (~5 × 109 K/s) quenches the film, permitting in-situ, post-mortem analysis using a variety of surface science techniques. Lateral variations in the laser pulse energy are ~ ± 3% leading to a temperature uncertainty of ~ ± 5 K for a temperature jump of 200 K. Initial experiments with the apparatus demonstrate that crystalline ice films initially held at 90 K can be rapidly transformed into liquid water films with T > 273 K. No discernable recrystallization occurs during the rapid cooling back to cryogenic temperatures. In contrast, amorphous solid water films heated below the melting point rapidly crystallize. The nanosecond pulsed laser heating system can prepare nanoscale liquid and supercooled liquid films that persist for nanoseconds per heat pulse in an UHV environment, enabling experimental studies of a wide range of phenomena in liquids and at liquid/solid interfaces.

  6. Optical emission studies of plasma induced by single and double femtosecond laser pulses

    Energy Technology Data Exchange (ETDEWEB)

    Pinon, V. [Institute of Electronic Structure and Laser, Foundation for Research and Technology-Hellas (IESL-FORTH), P.O. Box 1385, 71110 Heraklion, Crete (Greece); Universidad de A Coruna, Departamento de Ingenieria Industrial II, E-15403 Ferrol, A Coruna (Spain); Anglos, D., E-mail: anglos@iesl.forth.g [Institute of Electronic Structure and Laser, Foundation for Research and Technology-Hellas (IESL-FORTH), P.O. Box 1385, 71110 Heraklion, Crete (Greece); Department of Chemistry, University of Crete, 71003 Heraklion, Crete (Greece)

    2009-10-15

    Double-pulse femtosecond laser ablation has been shown to lead to significant increase of the intensity and reproducibility of the optical emission signal compared to single-pulse ablation particularly when an appropriate interpulse delay is selected, that is typically in the range of 50-1000 ps. This effect can be especially advantageous in the context of femtosecond laser-induced breakdown spectroscopy analysis of materials. A detailed comparative study of collinear double- over single-pulse femtosecond laser-induced breakdown spectroscopy has been carried out, based on measurements of emission lifetime, temperature and electronic density of plasmas, produced during laser ablation of brass with 450 fs laser pulses at 248 nm. The results obtained show a distinct increase of plasma temperature and electronic density as well as a longer decay time in the double-pulse case. The plasma temperature increase is in agreement with the observed dependence of the emission intensity enhancement on the upper energy level of the corresponding spectral line. Namely, intensity enhancement of emission lines originating from higher lying levels is more profound compared to that of lines arising from lower energy levels. Finally, a substantial decrease of the plasma threshold fluence was observed in the double-pulse arrangement; this enables sensitive analysis with minimal damage on the sample surface.

  7. Moessbauer and XRD study of pulse plated Fe-P and Fe-Ni thin layers

    Energy Technology Data Exchange (ETDEWEB)

    Miko, Annamaria [Bay Zoltan Institute for Material Science (Hungary); Kuzmann, Erno, E-mail: kuzmann@para.chem.elte.hu [Eoetvoes Lorand University, Research Group for Nuclear Methods in Structural Chemistry, Hungarian Academy of Sciences, Department of Nuclear Chemistry (Hungary); Lakatos-Varsanyi, Magda [Bay Zoltan Institute for Material Science (Hungary); Kakay, Attila [Research Institute for Solid State Physics and Optics (Hungary); Nagy, Ferenc [Eoetvoes Lorand University, Research Group for Nuclear Methods in Structural Chemistry, Hungarian Academy of Sciences, Department of Nuclear Chemistry (Hungary); Varga, Lajos Karoly [Research Institute for Solid State Physics and Optics (Hungary)

    2005-09-15

    {sup 57}Fe conversion electron Moessbauer spectroscopy, X-ray diffraction, electrochemical and magnetic measurements were used to study pulse electroplated Fe-P and Ni-Fe coatings. XRD and {sup 57}Fe CEMS measurements revealed the amorphous character of the novel pulse plated Fe-P alloys. CEM spectra indicated significant differences in the short range order and in the magnetic anisotropy between the Fe-P deposits pulse plated at medium long deposition time (t{sub on} = 2 ms), with short relaxation time (t{sub off} = 9 ms) and low current density (I{sub p} = 0.05 Acm{sup -2}) or at short deposition time (t{sub on} = 1 ms) with long relaxation time (t{sub off} = 250 ms) and high current density (I{sub p} = 1.0 Acm{sup -2}). The broad peaks centred around the fcc reflections in XRD of the pulse plated Ni-22 wt.% Fe deposit reflected a microcrystalline Ni-Fe alloy with a very fine, 5-8 nm, grain size. The CEM spectrum of the pulse plated Ni-22 wt.% Fe coating corresponded to a highly disordered solid solution alloy containing a minute amount of ferrihydrite. Extreme favourable soft magnetic properties were observed with these Ni-Fe and Fe-P pulse plated thin layers.

  8. Proof-of-principle pilot study of oropharyngeal air-pulse application in individuals with dysphagia after hemispheric stroke.

    Science.gov (United States)

    Theurer, Julie A; Johnston, Jennifer L; Fisher, James; Darling, Sherry; Stevens, Rebecca C; Taves, Donald; Teasell, Robert; Hachinski, Vladimir; Martin, Ruth E

    2013-06-01

    To test the hypothesis that oropharyngeal air-pulse application is associated with increased swallowing rates in individuals with dysphagia secondary to stroke. Case control. Stroke rehabilitation hospital or home setting. Convenience sample of individuals (N=8) with new-onset dysphagia after stroke. Air-pulse trains were applied to the oropharynx of 8 subjects who presented with dysphagia after hemispheric stroke. Resting swallowing rates were determined for 5 experimental conditions: baseline without air-pulse mouthpiece, baseline with mouthpiece in situ, unilateral right oropharyngeal air-pulse, unilateral left oropharyngeal air-pulse, and bilateral oropharyngeal air-pulse application. Individual swallowing responses were analyzed using a 2-SD band method. Swallowing rate (swallows/min). Swallowing rates associated with bilateral air-pulse application were greater than baseline in 4 of the 8 subjects. The 4 subjects who demonstrated this response to air-pulse application had greater baseline swallowing rates than did subjects whose swallowing rates were not altered in association with air-pulse application. Oropharyngeal air-pulse trains can be applied in individuals with swallowing impairment. Air-pulse application is associated with increased resting swallowing rates in some individuals with dysphagia secondary to hemispheric stroke. Further research should extend this proof-of-principle study by examining the efficacy of oropharyngeal air-pulse application in terms of improved swallowing and related outcomes in dysphagic stroke through a large randomized trial. Copyright © 2013 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

  9. A Comparative Study of Single-pulse and Double-pulse Laser-Induced Breakdown Spectroscopy with Uranium-containing Samples

    Energy Technology Data Exchange (ETDEWEB)

    Skrodzki, P. J.; Becker, J. R.; Diwakar, P. K.; Harilal, S. S.; Hassanein, A.

    2016-01-25

    Laser-induced breakdown spectroscopy (LIBS) holds potential advantages in special nuclear material (SNM) sensing and nuclear forensics which require rapid analysis, minimal sample preparation and stand-off distance capability. SNM, such as U, however, result in crowded emission spectra with LIBS, and characteristic emission lines are challenging to discern. It is well-known that double-pulse LIBS (DPLIBS) improves the signal intensity for analytes over conventional single-pulse LIBS (SPLIBS). This study investigates U signal in a glass matrix using DPLIBS and compares to signal features obtained using SPLIBS. DPLIBS involves sequential firing of 1.06 µm Nd:YAG pre-pulse and 10.6 µm TEA CO2 heating pulse in near collinear geometry. Optimization of experimental parameters including inter-pulse delay and energy follows identification of characteristic lines and signals for bulk analyte Ca and minor constituent analyte U for both DPLIBS and SPLIBS. Spatial and temporal coupling of the two pulses in the proposed DPLIBS technique yields improvements in analytical merits with negligible further damage to the sample compared to SPLIBS. Subsequently, the study discusses optimum plasma emission conditions of U lines and relative figures of merit in both SPLIBS and DPLIBS. Investigation into plasma characteristics also addresses plausible mechanisms related to observed U analyte signal variation between SPLIBS and DPLIBS.

  10. Comparison of two photosensitizers in photodynamic therapy using light pulses in femtosecond regime: an animal study

    Science.gov (United States)

    Grecco, Clóvis; Pratavieira, Sebastião.; Bagnato, Vanderlei; Kurachi, Cristina

    2016-03-01

    Photodynamic therapy is a therapeutic modality for cancer treatment based on the interaction of light with a sensitizer agent and molecular oxygen present into the target cells. The aim of this study is the evaluation of photodynamic therapy using pulsed light source in the femtosecond regime through necrosis induced in healthy rat liver. The induced necrosis profile with CW laser and pulsed laser were evaluated in animal model, which received Photodithazine (chlorine e6 derivative). The light sources used in these studies were a 660 nm CW diode laser and a Ti:Sapphire Regenerative Amplifier laser (1 kHz repetition rate and 100 fs pulse width) associated with an optical parametric amplifier (OPA) to convert to 660 nm. The results were compared with a previous study when was used a hematoporphyrin derivative (Photogem) as a sensitizer. The induced necrosis with Photogen was greater with pulsed laser (2.0 +/- 0.2 mm) in comparison with CW laser (1.0 ± 0.2 mm), while in Photodithazine the induced necrosis with was greater with CW laser (2.9 +/- 0.2 mm) comparing the pulsed laser (2.0 +/- 0.2 mm). These results indicate dependence of PDT mechanisms with photosensitizer and the light regime applied.

  11. Numerical and experimental study of pulse-jet cleaning in fabric filters

    DEFF Research Database (Denmark)

    O. Andersen, B.; Nielsen, N. F.; Walther, J. H.

    2016-01-01

    for many years by experimental investigation and to a limited extent by Computational Fluid Dynamics (CFD). The majority of the studies have focused on high-pressure cleaning systems, and the CFD models presented are so far two-dimensional (2D). In the work presented here, pulse-jet cleaning of low......Pulse-jet cleaning and understanding of the complex physics are essential when designing fabric filters used for air pollution control. Today, low-pressure cleaning is of particular interest due to demand for reduced compressed air consumption. Pulse-jet cleaned fabric filters have been studied......-pressure fabric filters (2 bar) is studied using a full three-dimensional (3D) CFD model. Experimental results obtained in a pilot-scale test filter with 28 bags, in length of 10 m and in general full-scale dimensions of the cleaning system are used to verify the reliability of the present CFD model...

  12. Pulse on Pulse

    DEFF Research Database (Denmark)

    Schmidt, Ulrik; Carlson, Merete

    2012-01-01

    Pulse on Pulse” investigates the relation between signifying processes and non-signifying material dynamism in the installation Pulse Room (2006-) by Mexican Canadian artist Rafael Lozano-Hemmer. In Pulse Room the sense of pulse is ambiguous. Biorhythms are transmitted from the pulsing energy...... and pulsating ‘room’. Hence, the visitors in Pulse Room are invited into a complex scenario that continuously oscillates between various aspects of signification (the light bulbs representing individual lives; the pulse itself as the symbolic ‘rhythm of life’) and instants of pure material processuality...... a multilayered sense of time and space that is central to the sensory experience of Pulse Room as a whole. Pulse Room is, at the very same time, an anthropomorfized archive of a past intimacy and an all-encompassing immersive environment modulating continuously in real space-time....

  13. Pulsed dye laser versus long pulsed Nd:YAG laser in the treatment of angiokeratoma of Fordyce: A randomized, comparative, observer-blinded study.

    Science.gov (United States)

    Ibrahim, S M

    2016-01-01

    Angiokeratoma of Fordyce is typically asymptomatic, blue-to-red papules with a scaly surface located on the scrotum, shaft of penis or labia majora. They can be treated with some locally destructive treatment modalities such as excision, electrocoagulation, cryotherapy and laser. To compare the effects of the pulsed dye laser versus long pulsed Nd:YAG laser in the treatment of angiokeratoma of Fordyce. Twenty tow patients with angiokeratoma of Fordyce were included in this study. All participants received three sessions of pulsed dye laser on the selected side or part of lesional area and long pulsed Nd:YAG laser on the other side or part of lesional area. Two dermatologists independently evaluated the photographs of the baseline and two-month follow-up after last session using a grade system in which treatment response was categorized into six grades. Both PDL and long pulsed Nd:YAG laser revealed statistically significant improvements in angiokeratoma of fordyce. Comparatively, there was a statistical difference between them (overall mean improvement with PDL, 61.8%, versus Nd:YAG, 77.63%; p laser are effective and safe in the treatment of angiokeratoma of Fordyce with better response in Nd:YAG laser than pulsed dye laser.

  14. Experimental study of polarity dependence in repetitive nanosecond-pulse breakdown

    Institute of Scientific and Technical Information of China (English)

    Shao Tao; Sun Guang-Sheng; Yan Ping; Wang Jue; Yuan Wei-Qun; Zhang Shi-Chang

    2007-01-01

    Pulsed breakdown of dry air at ambient pressure has been investigated in the point-plane geometry,using repetitive nanosecond pulses with 10 ns risetime,20-30 as duration,and up to 100 kV amplitude.A major concern in this paper is to study the dependence of breakdown strength on the point-electrode polarity.Applied voltage,breakdown current and repetitive stressing time are measured under the experimental conditions of some variables including pulse voltage peak,gap spacing and repetition rate.The results show that increasing the E-field strength can decrease breakdown time lag,repetitive stressing time and the number of applied pulses as expected.However,compared with the traditional polarity dependence it is weakened and not significant in the repetitive nanosecond-pulse breakdown.The ambiguous polaxity dependence in the experimental study is involved with an accumulation effect of residual charges and metastable states.Moreover,it is suggested that the reactions associated with the detachment of negative ions and impact deactivation of metastable specms could provide a source of primary initiating electrons for breakdown.

  15. Raman study of TiO2 coatings modified by UV pulsed laser

    Science.gov (United States)

    Belka, Radosław; Keczkowska, Justyna; Sek, Piotr

    2016-12-01

    The TiO2 coatings were prepared by simple sol-gel method and modified by UV pulsed laser. TiO2, also know as titania, is a ceramic compound, existing in numerous polymorphic forms, mainly as tetragonal rutile and anatase, and rhomboidal brookite. Rutile is the most stable form of titanium dioxide, whereas anatase is a metastable form, created in lower temperatures than rutile. Anatase is marked with higher specific surface area, porosity and a higher number of surface hydroxyl groups as compared to rutile. The unique optical and electronic properties of TiO2 results in its use as semiconductors dielectric mirrors, sunscreen and UV-blocking pigments and especially as photocatalyst. In this paper, the tetraisopropoxide was used as Ti precursor according to sol-gel method. An organic base was applied during sol preparation. Prepared gel was coated on glass substrates and calcined in low temperature to obtain amorphous phase of titania. Prepared coatings were modified by UV picosecond pulse laser with different pulse repetition rate and pulse power. Physical modification of the coatings using laser pulses was intended in order change the phase content of the produced material. Raman spectroscopy (RS) method was applied to studies of modified coatings as it is one of the basic analytical techniques, supporting the identification of compounds and obtaining information about the structure. Especially, RS is a useful method for distinguishing the anatase and rutile phases. In these studies, anatase to rutile transformation was observed, depending on laser parameters.

  16. Pulse wave velocity in patients with severe head injury a pilot study.

    Science.gov (United States)

    Shahsavari, S; McKelvey, T; Rydenhag, B; Ritzén, C Eriksson

    2010-01-01

    The study aimed to determine the potential of pulse wave velocity measurements to reflect changes in compliant cerebral arteries/arterioles in head injured patients. The approach utilizes the electrocardiogram and intracranial pressure signals to measure the wave transit time between heart and cranial cavity. Thirty five clinical records of nineteen head injured patients, with different levels of cerebrovascular pressure-reactivity response, were investigated through the study. Results were compared with magnitude of normalized transfer function at the fundamental cardiac frequency. In patients with intact cerebrovascular pressure-reactivity, magnitude of normalized transfer function at the fundamental cardiac component was found to be highly correlated with pulse wave transit time.

  17. A high-field pulsed magnet system for x-ray scattering studies in Voigt geometry

    CERN Document Server

    Islam, Zahirul; Ruff, Jacob P C; Das, Ritesh K; Trakhtenberg, Emil; Nojiri, Hiroyuki; Narumi, Yasuo; Canfield, Paul C

    2011-01-01

    We present a new pulsed-magnet system that enables x-ray single-crystal diffraction in addition to powder and spectroscopic studies in Voigt geometry. The apparatus consists of a large-bore solenoid, cooled by liquid nitrogen. A second independent closed-cycle cryostat is used for cooling samples near liquid helium temperatures. Pulsed magnetic fields up to ~30 T with a minimum of ~6 ms in total duration are generated by discharging a 40 kJ capacitor bank into the magnet coil. The unique characteristic of this instrument is the preservation of maximum scattering angle (~23.6 deg.) through the magnet bore by virtue of a novel double-funnel insert. This instrument would facilitate x-ray diffraction and spectroscopic studies that are impractical, if not impossible, to perform using conventional split-pair magnets and offers a practical solution for preserving optical access in future higher-field pulsed magnets.

  18. Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

    NARCIS (Netherlands)

    Wain, Louise V.; Verwoert, Germaine C.; O'Reilly, Paul F.; Shi, Gang; Johnson, Toby; Johnson, Andrew D.; Bochud, Murielle; Rice, Kenneth M.; Henneman, Peter; Smith, Albert V.; Ehret, Georg B.; Amin, Najaf; Larson, Martin G.; Mooser, Vincent; Hadley, David; Doerr, Marcus; Bis, Joshua C.; Aspelund, Thor; Esko, Tonu; Janssens, A. Cecile J. W.; Zhao, Jing Hua; Heath, Simon; Laan, Maris; Fu, Jingyuan; Pistis, Giorgio; Luan, Jian'an; Arora, Pankaj; Lucas, Gavin; Pirastu, Nicola; Pichler, Irene; Jackson, Anne U.; Webster, Rebecca J.; Zhang, Feng; Peden, John F.; Schmidt, Helena; Tanaka, Toshiko; Campbell, Harry; Igl, Wilmar; Milaneschi, Yuri; Hottenga, Jouke-Jan; Vitart, Veronique; Chasman, Daniel I.; Trompet, Stella; Bragg-Gresham, Jennifer L.; Alizadeh, Behrooz Z.; Chambers, John C.; Guo, Xiuqing; Lehtimaki, Terho; Kuehnel, Brigitte; Lopez, Lorna M.; Polasek, Ozren; Boban, Mladen; Nelson, Christopher P.; Morrison, Alanna C.; Pihur, Vasyl; Ganesh, Santhi K.; Hofman, Albert; Kundu, Suman; Mattace-Raso, Francesco U. S.; Rivadeneira, Fernando; Sijbrands, Eric J. G.; Uitterlinden, Andre G.; Hwang, Shih-Jen; Vasan, Ramachandran S.; Wang, Thomas J.; Bergmann, Sven; Vollenweider, Peter; Waeber, Gerard; Laitinen, Jaana; Pouta, Anneli; Zitting, Paavo; McArdle, Wendy L.; Kroemer, Heyo K.; Voelker, Uwe; Voelzke, Henry; Glazer, Nicole L.; Taylor, Kent D.; Harris, Tamara B.; Alavere, Helene; Haller, Toomas; Keis, Aime; Tammesoo, Mari-Liis; Aulchenko, Yurii; Barroso, Ines; Khaw, Kay-Tee; Galan, Pilar; Hercberg, Serge; Lathrop, Mark; Eyheramendy, Susana; Org, Elin; Sober, Siim; Lu, Xiaowen; Nolte, Ilja M.; Penninx, Brenda W.; Corre, Tanguy; Masciullo, Corrado; Sala, Cinzia; Groop, Leif; Voight, Benjamin F.; Melander, Olle; O'Donnell, Christopher J.; Salomaa, Veikko; d'Adamo, Adamo Pio; Fabretto, Antonella; Faletra, Flavio; Ulivi, Sheila; Del Greco, Fabiola M.; Facheris, Maurizio; Collins, Francis S.; Bergman, Richard N.; Beilby, John P.; Hung, Joseph; Musk, A. William; Mangino, Massimo; Shin, So-Youn; Soranzo, Nicole; Watkins, Hugh; Goel, Anuj; Hamsten, Anders; Gider, Pierre; Loitfelder, Marisa; Zeginigg, Marion; Hernandez, Dena; Najjar, Samer S.; Navarro, Pau; Wild, Sarah H.; Corsi, Anna Maria; Singleton, Andrew; de Geus, Eco J. C.; Willemsen, Gonneke; Parker, Alex N.; Rose, Lynda M.; Buckley, Brendan; Stott, David; Orru, Marco; Uda, Manuela; van der Klauw, Melanie M.; Zhang, Weihua; Li, Xinzhong; Scott, James; Chen, Yii-Der Ida; Burke, Gregory L.; Kahonen, Mika; Viikari, Jorma; Doering, Angela; Meitinger, Thomas; Davies, Gail; Starr, John M.; Emilsson, Valur; Plump, Andrew; Lindeman, Jan H.; 't Hoen, Peter A. C.; Koenig, Inke R.; Felix, Janine F.; Clarke, Robert; Hopewell, Jemma C.; Ongen, Halit; Breteler, Monique; Debette, Stephanie; DeStefano, Anita L.; Fornage, Myriam; Mitchell, Gary F.; Smith, Nicholas L.; Holm, Hilma; Stefansson, Kari; Thorleifsson, Gudmar; Thorsteinsdottir, Unnur; Samani, Nilesh J.; Preuss, Michael; Rudan, Igor; Hayward, Caroline; Deary, Ian J.; Wichmann, H-Erich; Raitakari, Olli T.; Palmas, Walter; Kooner, Jaspal S.; Stolk, Ronald P.; Jukema, J. Wouter; Wright, Alan F.; Boomsma, Dorret I.; Bandinelli, Stefania; Gyllensten, Ulf B.; Wilson, James F.; Ferrucci, Luigi; Schmidt, Reinhold; Farrall, Martin; Spector, Tim D.; Palmer, Lyle J.; Tuomilehto, Jaakko; Pfeufer, Arne; Gasparini, Paolo; Siscovick, David; Altshuler, David; Loos, Ruth J. F.; Toniolo, Daniela; Snieder, Harold; Gieger, Christian; Meneton, Pierre; Wareham, Nicholas J.; Oostra, Ben A.; Metspalu, Andres; Launer, Lenore; Rettig, Rainer; Strachan, David P.; Beckmann, Jacques S.; Witteman, Jacqueline C. M.; Erdmann, Jeanette; van Dijk, Ko Willems; Boerwinkle, Eric; Boehnke, Michael; Ridker, Paul M.; Jarvelin, Marjo-Riitta; Chakravarti, Aravinda; Abecasis, Goncalo R.; Gudnason, Vilmundur; Newton-Cheh, Christopher; Levy, Daniel; Munroe, Patricia B.; Psaty, Bruce M.; Caulfield, Mark J.; Rao, Dabeeru C.; Tobin, Martin D.; Elliott, Paul; van Duijn, Cornelia M.

    2011-01-01

    Numerous genetic loci have been associated with systolic blood pressure (SBP) and diastolic blood pressure (DBP) in Europeans(1-3). We now report genome-wide association studies of pulse pressure (PP) and mean arterial pressure (MAP). In discovery (N = 74,064) and follow-up studies (N = 48,607), we

  19. Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

    NARCIS (Netherlands)

    L.V. Wain (Louise); G.C. Verwoert (Germaine); P.F. O'Reilly (Paul); G. Shi (Gang); T. Johnson (Toby); M. Bochud (Murielle); K. Rice (Kenneth); P. Henneman (Peter); A.V. Smith (Albert Vernon); G.B. Ehret (Georg); N. Amin (Najaf); M.G. Larson (Martin); V. Mooser (Vincent); D. Hadley (David); M. Dörr (Marcus); J.C. Bis (Joshua); T. Aspelund (Thor); T. Esko (Tõnu); A.C.J.W. Janssens (Cécile); J.H. Zhao; S.C. Heath (Simon); M. Laan (Maris); J. Fu (Jingyuan); G. Pistis (Giorgio); J. Luan; G. Lucas (Gavin); N. Pirastu (Nicola); I. Pichler (Irene); A.U. Jackson (Anne); R.J. Webster (Rebecca J.); F.F. Zhang; J. Peden (John); R. Schmidt (Reinhold); T. Tanaka (Toshiko); H. Campbell (Harry); W. Igl (Wilmar); Y. Milaneschi (Yuri); J.J. Hottenga (Jouke Jan); V. Vitart (Veronique); D.I. Chasman (Daniel); S. Trompet (Stella); J.L. Bragg-Gresham (Jennifer L.); B.Z. Alizadeh (Behrooz); J.C. Chambers (John); X. Guo (Xiuqing); T. Lehtimäki (Terho); B. Kuhnel (Brigitte); L.M. Lopez; O. Polasek (Ozren); M. Boban (Mladen); C.P. Nelson (Christopher P.); A.C. Morrison (Alanna); V. Pihur (Vasyl); S.K. Ganesh (Santhi); A. Hofman (Albert); S. Kundu (Suman); F.U.S. Mattace Raso (Francesco); F. Rivadeneira Ramirez (Fernando); E.J.G. Sijbrands (Eric); A.G. Uitterlinden (André); S.J. Hwang; R.S. Vasan (Ramachandran Srini); Y.A. Wang (Ying); S.M. Bergmann (Sven); P. Vollenweider (Peter); G. Waeber (Gérard); J. Laitinen (Jaana); A. Pouta (Anneli); P. Zitting (Paavo); W.L. McArdle (Wendy); H.K. Kroemer (Heyo); U. Völker (Uwe); H. Völzke (Henry); N.L. Glazer (Nicole); K.D. Taylor (Kent); T.B. Harris (Tamara); H. Alavere (Helene); T. Haller (Toomas); A. Keis (Aime); M.L. Tammesoo; Y.S. Aulchenko (Yurii); K-T. Khaw (Kay-Tee); P. Galan (Pilar); S. Hercberg (Serge); G.M. Lathrop (Mark); S. Eyheramendy (Susana); E. Org (Elin); S. Sõber (Siim); X. Lu (Xiaowen); I.M. Nolte (Ilja); B.W.J.H. Penninx (Brenda); T. Corre (Tanguy); C. Masciullo (Corrado); C. Sala (Cinzia); L. Groop (Leif); B.F. Voight (Benjamin); O. Melander (Olle); C.J. O'Donnell (Christopher); V. Salomaa (Veikko); P. d' Adamo (Pio); A. Fabretto (Antonella); F. Faletra (Flavio); S. Ulivi (Shelia); F. Del Greco M (Fabiola); M.F. Facheris (Maurizio); F.S. Collins (Francis); R.N. Bergman (Richard); J.P. Beilby (John); J. Hung (Judy); A.W. Musk (Arthur); M. Mangino (Massimo); S.Y. Shin (So Youn); N. Soranzo (Nicole); H. Watkins (Hugh); A. Goel (Anuj); A. Hamsten (Anders); P. Gider (Pierre); M. Loitfelder (Marisa); M. Zeginigg (Marion); D.G. Hernandez (Dena); S.S. Najjar (Samer); P. Navarro (Pau); S.H. Wild (Sarah); A.M. Corsi (Anna Maria); A. Singleton (Andrew); E.J.C. de Geus (Eco); G.A.H.M. Willemsen (Gonneke); A.N. Parker (Alex); L.M. Rose (Lynda); B.M. Buckley (Brendan M.); D.J. Stott (David. J.); M. Orrù (Marco); M. Uda (Manuela); M.M. van der Klauw (Melanie); X. Li (Xiaohui); J. Scott (James); Y.D.I. Chen (Yii-Der Ida); G.L. Burke (Greg); M. Kähönen (Mika); J. Viikari (Jorma); A. Döring (Angela); T. Meitinger (Thomas); G.S. Davis; J.M. Starr (John); V. Emilsson (Valur); A.S. Plump (Andrew); J.H. Lindeman (Jan H.); P.A.C. 't Hoen (Peter); I.R. König (Inke); J.F. Felix (Janine); R. Clarke; J. Hopewell; H. Ongen (Halit); M.M.B. Breteler (Monique); S. Debette (Stéphanie); A.L. DeStefano (Anita); M. Fornage (Myriam); G.F. Mitchell (Gary); H. Holm (Hilma); K. Stefansson (Kari); G. Thorleifsson (Gudmar); U. Thorsteinsdottir (Unnur); N.J. Samani (Nilesh); M. Preuss (Michael); I. Rudan (Igor); C. Hayward (Caroline); I.J. Deary (Ian); H.E. Wichmann (Heinz Erich); O. Raitakari (Olli); W. Palmas (Walter); J.S. Kooner (Jaspal); R.P. Stolk (Ronald); J.W. Jukema (Jan Wouter); A.F. Wright (Alan); D.I. Boomsma (Dorret); S. Bandinelli (Stefania); U. Gyllensten (Ulf); J.F. Wilson (James); L. Ferrucci (Luigi); M. Farrall (Martin); T.D. Spector (Timothy); L.J. Palmer; J. Tuomilehto (Jaakko); A. Pfeufer (Arne); P. Gasparini (Paolo); D.S. Siscovick (David); D. Altshuler (David); R.J.F. Loos (Ruth); D. Toniolo (Daniela); H. Snieder (Harold); C. Gieger (Christian); P. Meneton (Pierre); N.J. Wareham (Nick); B.A. Oostra (Ben); A. Metspalu (Andres); L.J. Launer (Lenore); R. Rettig (Rainer); D.P. Strachan (David); J.S. Beckmann (Jacques); J.C.M. Witteman (Jacqueline); J.A.P. Willems van Dijk (Ko); E.A. Boerwinkle (Eric); M. Boehnke (Michael); P.M. Ridker (Paul); M.R. Järvelin; A. Chakravarti (Aravinda); J. Erdmann (Jeanette); V. Gudnason (Vilmundur); C. Newton-Cheh (Christopher); D. Levy (Daniel); P. Arora (Pankaj)

    2011-01-01

    textabstractNumerous genetic loci have been associated with systolic blood pressure (SBP) and diastolic blood pressure (DBP) in Europeans. We now report genome-wide association studies of pulse pressure (PP) and mean arterial pressure (MAP). In discovery (N = 74,064) and follow-up studies (N =

  20. Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

    NARCIS (Netherlands)

    Wain, Louise V; Verwoert, Germaine C; O'Reilly, Paul F; Shi, Gang; Johnson, Toby; Johnson, Andrew D; Bochud, Murielle; Rice, Kenneth M; Henneman, Peter; Smith, Albert V; Ehret, Georg B; Amin, Najaf; Larson, Martin G; Mooser, Vincent; Hadley, David; Dörr, Marcus; Bis, Joshua C; Aspelund, Thor; Esko, Tõnu; Janssens, A Cecile J W; Zhao, Jing Hua; Heath, Simon; Laan, Maris; Fu, Jingyuan; Pistis, Giorgio; Luan, Jian'an; Arora, Pankaj; Lucas, Gavin; Pirastu, Nicola; Pichler, Irene; Jackson, Anne U; Webster, Rebecca J; Zhang, Feng; Peden, John F; Schmidt, Helena; Tanaka, Toshiko; Campbell, Harry; Igl, Wilmar; Milaneschi, Yuri; Hottenga, Jouke-Jan; Vitart, Veronique; Chasman, Daniel I; Trompet, Stella; Bragg-Gresham, Jennifer L; Alizadeh, Behrooz Z; Chambers, John C; Guo, Xiuqing; Lehtimäki, Terho; Kühnel, Brigitte; Lopez, Lorna M; Polašek, Ozren; Boban, Mladen; Nelson, Christopher P; Morrison, Alanna C; Pihur, Vasyl; Ganesh, Santhi K; Hofman, Albert; Kundu, Suman; Mattace-Raso, Francesco U S; Rivadeneira, Fernando; Sijbrands, Eric J G; Uitterlinden, Andre G; Hwang, Shih-Jen; Vasan, Ramachandran S; Wang, Thomas J; Bergmann, Sven; Vollenweider, Peter; Waeber, Gérard; Laitinen, Jaana; Pouta, Anneli; Zitting, Paavo; McArdle, Wendy L; Kroemer, Heyo K; Völker, Uwe; Völzke, Henry; Glazer, Nicole L; Taylor, Kent D; Harris, Tamara B; Alavere, Helene; Haller, Toomas; Keis, Aime; Tammesoo, Mari-Liis; Aulchenko, Yurii; Barroso, Inês; Khaw, Kay-Tee; Galan, Pilar; Hercberg, Serge; Lathrop, Mark; Eyheramendy, Susana; Org, Elin; Sõber, Siim; Lu, Xiaowen; Nolte, Ilja M; Penninx, Brenda W; Corre, Tanguy; Masciullo, Corrado; Sala, Cinzia; Groop, Leif; Voight, Benjamin F; Melander, Olle; O'Donnell, Christopher J; Salomaa, Veikko; d'Adamo, Adamo Pio; Fabretto, Antonella; Faletra, Flavio; Ulivi, Sheila; Del Greco, Fabiola M; Facheris, Maurizio; Collins, Francis S; Bergman, Richard N; Beilby, John P; Hung, Joseph; Musk, A William; Mangino, Massimo; Shin, So-Youn; Soranzo, Nicole; Watkins, Hugh; Goel, Anuj; Hamsten, Anders; Gider, Pierre; Loitfelder, Marisa; Zeginigg, Marion; Hernandez, Dena; Najjar, Samer S; Navarro, Pau; Wild, Sarah H; Corsi, Anna Maria; Singleton, Andrew; de Geus, Eco J C; Willemsen, Gonneke; Parker, Alex N; Rose, Lynda M; Buckley, Brendan; Stott, David; Orru, Marco; Uda, Manuela; van der Klauw, Melanie M; Zhang, Weihua; Li, Xinzhong; Scott, James; Chen, Yii-Der Ida; Burke, Gregory L; Kähönen, Mika; Viikari, Jorma; Döring, Angela; Meitinger, Thomas; Davies, Gail; Starr, John M; Emilsson, Valur; Plump, Andrew; Lindeman, Jan H; Hoen, Peter A C 't; König, Inke R; Felix, Janine F; Clarke, Robert; Hopewell, Jemma C; Ongen, Halit; Breteler, Monique; Debette, Stéphanie; Destefano, Anita L; Fornage, Myriam; Mitchell, Gary F; Smith, Nicholas L; Holm, Hilma; Stefansson, Kari; Thorleifsson, Gudmar; Thorsteinsdottir, Unnur; Samani, Nilesh J; Preuss, Michael; Rudan, Igor; Hayward, Caroline; Deary, Ian J; Wichmann, H-Erich; Raitakari, Olli T; Palmas, Walter; Kooner, Jaspal S; Stolk, Ronald P; Jukema, J Wouter; Wright, Alan F; Boomsma, Dorret I; Bandinelli, Stefania; Gyllensten, Ulf B; Wilson, James F; Ferrucci, Luigi; Schmidt, Reinhold; Farrall, Martin; Spector, Tim D; Palmer, Lyle J; Tuomilehto, Jaakko; Pfeufer, Arne; Gasparini, Paolo; Siscovick, David; Altshuler, David; Loos, Ruth J F; Toniolo, Daniela; Snieder, Harold; Gieger, Christian; Meneton, Pierre; Wareham, Nicholas J; Oostra, Ben A; Metspalu, Andres; Launer, Lenore; Rettig, Rainer; Strachan, David P; Beckmann, Jacques S; Witteman, Jacqueline C M; Erdmann, Jeanette; van Dijk, Ko Willems; Boerwinkle, Eric; Boehnke, Michael; Ridker, Paul M; Jarvelin, Marjo-Riitta; Chakravarti, Aravinda; Abecasis, Goncalo R; Gudnason, Vilmundur; Newton-Cheh, Christopher; Levy, Daniel; Munroe, Patricia B; Psaty, Bruce M; Caulfield, Mark J; Rao, Dabeeru C; Tobin, Martin D; Elliott, Paul; van Duijn, Cornelia M

    2011-01-01

    Numerous genetic loci have been associated with systolic blood pressure (SBP) and diastolic blood pressure (DBP) in Europeans. We now report genome-wide association studies of pulse pressure (PP) and mean arterial pressure (MAP). In discovery (N = 74,064) and follow-up studies (N = 48,607), we ident

  1. Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

    NARCIS (Netherlands)

    Wain, Louise V.; Verwoert, Germaine C.; O'Reilly, Paul F.; Shi, Gang; Johnson, Toby; Johnson, Andrew D.; Bochud, Murielle; Rice, Kenneth M.; Henneman, Peter; Smith, Albert V.; Ehret, Georg B.; Amin, Najaf; Larson, Martin G.; Mooser, Vincent; Hadley, David; Doerr, Marcus; Bis, Joshua C.; Aspelund, Thor; Esko, Tonu; Janssens, A. Cecile J. W.; Zhao, Jing Hua; Heath, Simon; Laan, Maris; Fu, Jingyuan; Pistis, Giorgio; Luan, Jian'an; Arora, Pankaj; Lucas, Gavin; Pirastu, Nicola; Pichler, Irene; Jackson, Anne U.; Webster, Rebecca J.; Zhang, Feng; Peden, John F.; Schmidt, Helena; Tanaka, Toshiko; Campbell, Harry; Igl, Wilmar; Milaneschi, Yuri; Hottenga, Jouke-Jan; Vitart, Veronique; Chasman, Daniel I.; Trompet, Stella; Bragg-Gresham, Jennifer L.; Alizadeh, Behrooz Z.; Chambers, John C.; Guo, Xiuqing; Lehtimaki, Terho; Kuehnel, Brigitte; Lopez, Lorna M.; Polasek, Ozren; Boban, Mladen; Nelson, Christopher P.; Morrison, Alanna C.; Pihur, Vasyl; Ganesh, Santhi K.; Hofman, Albert; Kundu, Suman; Mattace-Raso, Francesco U. S.; Rivadeneira, Fernando; Sijbrands, Eric J. G.; Uitterlinden, Andre G.; Hwang, Shih-Jen; Vasan, Ramachandran S.; Wang, Thomas J.; Bergmann, Sven; Vollenweider, Peter; Waeber, Gerard; Laitinen, Jaana; Pouta, Anneli; Zitting, Paavo; McArdle, Wendy L.; Kroemer, Heyo K.; Voelker, Uwe; Voelzke, Henry; Glazer, Nicole L.; Taylor, Kent D.; Harris, Tamara B.; Alavere, Helene; Haller, Toomas; Keis, Aime; Tammesoo, Mari-Liis; Aulchenko, Yurii; Barroso, Ines; Khaw, Kay-Tee; Galan, Pilar; Hercberg, Serge; Lathrop, Mark; Eyheramendy, Susana; Org, Elin; Sober, Siim; Lu, Xiaowen; Nolte, Ilja M.; Penninx, Brenda W.; Corre, Tanguy; Masciullo, Corrado; Sala, Cinzia; Groop, Leif; Voight, Benjamin F.; Melander, Olle; O'Donnell, Christopher J.; Salomaa, Veikko; d'Adamo, Adamo Pio; Fabretto, Antonella; Faletra, Flavio; Ulivi, Sheila; Del Greco, Fabiola M.; Facheris, Maurizio; Collins, Francis S.; Bergman, Richard N.; Beilby, John P.; Hung, Joseph; Musk, A. William; Mangino, Massimo; Shin, So-Youn; Soranzo, Nicole; Watkins, Hugh; Goel, Anuj; Hamsten, Anders; Gider, Pierre; Loitfelder, Marisa; Zeginigg, Marion; Hernandez, Dena; Najjar, Samer S.; Navarro, Pau; Wild, Sarah H.; Corsi, Anna Maria; Singleton, Andrew; de Geus, Eco J. C.; Willemsen, Gonneke; Parker, Alex N.; Rose, Lynda M.; Buckley, Brendan; Stott, David; Orru, Marco; Uda, Manuela; van der Klauw, Melanie M.; Zhang, Weihua; Li, Xinzhong; Scott, James; Chen, Yii-Der Ida; Burke, Gregory L.; Kahonen, Mika; Viikari, Jorma; Doering, Angela; Meitinger, Thomas; Davies, Gail; Starr, John M.; Emilsson, Valur; Plump, Andrew; Lindeman, Jan H.; 't Hoen, Peter A. C.; Koenig, Inke R.; Felix, Janine F.; Clarke, Robert; Hopewell, Jemma C.; Ongen, Halit; Breteler, Monique; Debette, Stephanie; DeStefano, Anita L.; Fornage, Myriam; Mitchell, Gary F.; Smith, Nicholas L.; Holm, Hilma; Stefansson, Kari; Thorleifsson, Gudmar; Thorsteinsdottir, Unnur; Samani, Nilesh J.; Preuss, Michael; Rudan, Igor; Hayward, Caroline; Deary, Ian J.; Wichmann, H-Erich; Raitakari, Olli T.; Palmas, Walter; Kooner, Jaspal S.; Stolk, Ronald P.; Jukema, J. Wouter; Wright, Alan F.; Boomsma, Dorret I.; Bandinelli, Stefania; Gyllensten, Ulf B.; Wilson, James F.; Ferrucci, Luigi; Schmidt, Reinhold; Farrall, Martin; Spector, Tim D.; Palmer, Lyle J.; Tuomilehto, Jaakko; Pfeufer, Arne; Gasparini, Paolo; Siscovick, David; Altshuler, David; Loos, Ruth J. F.; Toniolo, Daniela; Snieder, Harold; Gieger, Christian; Meneton, Pierre; Wareham, Nicholas J.; Oostra, Ben A.; Metspalu, Andres; Launer, Lenore; Rettig, Rainer; Strachan, David P.; Beckmann, Jacques S.; Witteman, Jacqueline C. M.; Erdmann, Jeanette; van Dijk, Ko Willems; Boerwinkle, Eric; Boehnke, Michael; Ridker, Paul M.; Jarvelin, Marjo-Riitta; Chakravarti, Aravinda; Abecasis, Goncalo R.; Gudnason, Vilmundur; Newton-Cheh, Christopher; Levy, Daniel; Munroe, Patricia B.; Psaty, Bruce M.; Caulfield, Mark J.; Rao, Dabeeru C.; Tobin, Martin D.; Elliott, Paul; van Duijn, Cornelia M.

    2011-01-01

    Numerous genetic loci have been associated with systolic blood pressure (SBP) and diastolic blood pressure (DBP) in Europeans(1-3). We now report genome-wide association studies of pulse pressure (PP) and mean arterial pressure (MAP). In discovery (N = 74,064) and follow-up studies (N = 48,607), we

  2. Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

    NARCIS (Netherlands)

    L.V. Wain (Louise); G.C. Verwoert (Germaine); P.F. O'Reilly (Paul); G. Shi (Gang); T. Johnson (Toby); M. Bochud (Murielle); K. Rice (Kenneth); P. Henneman (Peter); A.V. Smith (Albert Vernon); G.B. Ehret (Georg); N. Amin (Najaf); M.G. Larson (Martin); V. Mooser (Vincent); D. Hadley (David); M. Dörr (Marcus); J.C. Bis (Joshua); T. Aspelund (Thor); T. Esko (Tõnu); A.C.J.W. Janssens (Cécile); J.H. Zhao; S.C. Heath (Simon); M. Laan (Maris); J. Fu (Jingyuan); G. Pistis (Giorgio); J. Luan; G. Lucas (Gavin); N. Pirastu (Nicola); I. Pichler (Irene); A.U. Jackson (Anne); R.J. Webster (Rebecca J.); F.F. Zhang; J. Peden (John); R. Schmidt (Reinhold); T. Tanaka (Toshiko); H. Campbell (Harry); W. Igl (Wilmar); Y. Milaneschi (Yuri); J.J. Hottenga (Jouke Jan); V. Vitart (Veronique); D.I. Chasman (Daniel); S. Trompet (Stella); J.L. Bragg-Gresham (Jennifer L.); B.Z. Alizadeh (Behrooz); J.C. Chambers (John); X. Guo (Xiuqing); T. Lehtimäki (Terho); B. Kuhnel (Brigitte); L.M. Lopez; O. Polasek (Ozren); M. Boban (Mladen); C.P. Nelson (Christopher P.); A.C. Morrison (Alanna); V. Pihur (Vasyl); S.K. Ganesh (Santhi); A. Hofman (Albert); S. Kundu (Suman); F.U.S. Mattace Raso (Francesco); F. Rivadeneira Ramirez (Fernando); E.J.G. Sijbrands (Eric); A.G. Uitterlinden (André); S.J. Hwang; R.S. Vasan (Ramachandran Srini); Y.A. Wang (Ying); S.M. Bergmann (Sven); P. Vollenweider (Peter); G. Waeber (Gérard); J. Laitinen (Jaana); A. Pouta (Anneli); P. Zitting (Paavo); W.L. McArdle (Wendy); H.K. Kroemer (Heyo); U. Völker (Uwe); H. Völzke (Henry); N.L. Glazer (Nicole); K.D. Taylor (Kent); T.B. Harris (Tamara); H. Alavere (Helene); T. Haller (Toomas); A. Keis (Aime); M.L. Tammesoo; Y.S. Aulchenko (Yurii); K-T. Khaw (Kay-Tee); P. Galan (Pilar); S. Hercberg (Serge); G.M. Lathrop (Mark); S. Eyheramendy (Susana); E. Org (Elin); S. Sõber (Siim); X. Lu (Xiaowen); I.M. Nolte (Ilja); B.W.J.H. Penninx (Brenda); T. Corre (Tanguy); C. Masciullo (Corrado); C. Sala (Cinzia); L. Groop (Leif); B.F. Voight (Benjamin); O. Melander (Olle); C.J. O'Donnell (Christopher); V. Salomaa (Veikko); P. d' Adamo (Pio); A. Fabretto (Antonella); F. Faletra (Flavio); S. Ulivi (Shelia); F. Del Greco M (Fabiola); M.F. Facheris (Maurizio); F.S. Collins (Francis); R.N. Bergman (Richard); J.P. Beilby (John); J. Hung (Judy); A.W. Musk (Arthur); M. Mangino (Massimo); S.Y. Shin (So Youn); N. Soranzo (Nicole); H. Watkins (Hugh); A. Goel (Anuj); A. Hamsten (Anders); P. Gider (Pierre); M. Loitfelder (Marisa); M. Zeginigg (Marion); D.G. Hernandez (Dena); S.S. Najjar (Samer); P. Navarro (Pau); S.H. Wild (Sarah); A.M. Corsi (Anna Maria); A. Singleton (Andrew); E.J.C. de Geus (Eco); G.A.H.M. Willemsen (Gonneke); A.N. Parker (Alex); L.M. Rose (Lynda); B.M. Buckley (Brendan M.); D.J. Stott (David. J.); M. Orrù (Marco); M. Uda (Manuela); M.M. van der Klauw (Melanie); X. Li (Xiaohui); J. Scott (James); Y.D.I. Chen (Yii-Der Ida); G.L. Burke (Greg); M. Kähönen (Mika); J. Viikari (Jorma); A. Döring (Angela); T. Meitinger (Thomas); G.S. Davis; J.M. Starr (John); V. Emilsson (Valur); A.S. Plump (Andrew); J.H. Lindeman (Jan H.); P.A.C. 't Hoen (Peter); I.R. König (Inke); J.F. Felix (Janine); R. Clarke; J. Hopewell; H. Ongen (Halit); M.M.B. Breteler (Monique); S. Debette (Stéphanie); A.L. DeStefano (Anita); M. Fornage (Myriam); G.F. Mitchell (Gary); H. Holm (Hilma); K. Stefansson (Kari); G. Thorleifsson (Gudmar); U. Thorsteinsdottir (Unnur); N.J. Samani (Nilesh); M. Preuss (Michael); I. Rudan (Igor); C. Hayward (Caroline); I.J. Deary (Ian); H.E. Wichmann (Heinz Erich); O. Raitakari (Olli); W. Palmas (Walter); J.S. Kooner (Jaspal); R.P. Stolk (Ronald); J.W. Jukema (Jan Wouter); A.F. Wright (Alan); D.I. Boomsma (Dorret); S. Bandinelli (Stefania); U. Gyllensten (Ulf); J.F. Wilson (James); L. Ferrucci (Luigi); M. Farrall (Martin); T.D. Spector (Timothy); L.J. Palmer; J. Tuomilehto (Jaakko); A. Pfeufer (Arne); P. Gasparini (Paolo); D.S. Siscovick (David); D. Altshuler (David); R.J.F. Loos (Ruth); D. Toniolo (Daniela); H. Snieder (Harold); C. Gieger (Christian); P. Meneton (Pierre); N.J. Wareham (Nick); B.A. Oostra (Ben); A. Metspalu (Andres); L.J. Launer (Lenore); R. Rettig (Rainer); D.P. Strachan (David); J.S. Beckmann (Jacques); J.C.M. Witteman (Jacqueline); J.A.P. Willems van Dijk (Ko); E.A. Boerwinkle (Eric); M. Boehnke (Michael); P.M. Ridker (Paul); M.R. Järvelin; A. Chakravarti (Aravinda); J. Erdmann (Jeanette); V. Gudnason (Vilmundur); C. Newton-Cheh (Christopher); D. Levy (Daniel); P. Arora (Pankaj); P. Munroe (Patricia); B.M. Psaty (Bruce); M. Caulfield (Mark); D.C. Rao (Dabeeru C.); P. Elliott (Paul); P. Tikka-Kleemola (Päivi); G.R. Abecasis (Gonçalo); I. Barroso (Inês)

    2011-01-01

    textabstractNumerous genetic loci have been associated with systolic blood pressure (SBP) and diastolic blood pressure (DBP) in Europeans. We now report genome-wide association studies of pulse pressure (PP) and mean arterial pressure (MAP). In discovery (N = 74,064) and follow-up studies (N = 48,60

  3. A study of electrodischarge machining–pulse electrochemical machining combined machining for holes with high surface quality on superalloy

    Directory of Open Access Journals (Sweden)

    Ning Ma

    2015-11-01

    Full Text Available Noncircular holes on the surface of turbine rotor blades are usually machined by electrodischarge machining. A recast layer containing numerous micropores and microcracks is easily generated during the electrodischarge machining process due to the rapid heating and cooling effects, which restrict the wide applications of noncircular holes in aerospace and aircraft industries. Owing to the outstanding advantages of pulse electrochemical machining, electrodischarge machining–pulse electrochemical machining combined technique is provided to improve the overall quality of electrodischarge machining-drilled holes. The influence of pulse electrochemical machining processing parameters on the surface roughness and the influence of the electrodischarge machining–pulse electrochemical machining method on the surface quality and accuracy of holes have been studied experimentally. The results indicate that the pulse electrochemical machining processing time for complete removal of the recast layer decreases with the increase in the pulse electrochemical machining current. The low pulse electrochemical machining current results in uneven dissolution of the recast layer, while the higher pulse electrochemical machining current induces relatively homogeneous dissolution. The surface roughness is reduced from 4.277 to 0.299 µm, and the hole taper induced by top-down electrodischarge machining process was reduced from 1.04° to 0.17° after pulse electrochemical machining. On account of the advantages of electrodischarge machining and the pulse electrochemical machining, the electrodischarge machining–pulse electrochemical machining combined technique could be applied for machining noncircular holes with high shape accuracy and surface quality.

  4. Study on a Single-Stage 120 HZ Pulse Tube Cryocooler

    Science.gov (United States)

    Wu, Y. Z.; Gan, Z. H.; Qiu, L. M.; Chen, J.; Li, Z. P.

    2010-04-01

    Miniaturization of pulse tube cryocoolers is required for some particular applications where size and mass for devices are limited. In order to pack more cooling power in a small volume, higher operating frequencies are commonly used for Stirling-type pulse tube cryocoolers. To maintain high efficiency of the regenerator with a higher frequency, a higher charging pressure, smaller hydraulic diameters of regenerator material and a shorter regenerator length should be applied. A rapid growth of research and development on pulse tube cryocoolers operating at a high frequency over 100 Hz in the last 3 years has occurred. In this study, a single stage pulse tube cryocooler with 120 Hz to provide 10 W of lift at 80 K has been developed by using the numerical model, known as REGEN 3.2. Experiments performed on this cryocooler driven by a CFIC linear compressor show that a no-load temperature of 49.6 K was achieved and the net refrigeration power at 78.5 K was 8.0 W. The effect of pulse tube orientation was tested, and the copper velvet as a regenerator matrix was proposed for high frequency operation.

  5. Numerical Study of a 10 K Two Stage Pulse Tube Cryocooler with Precooling Inside the Pulse Tube

    Science.gov (United States)

    Xiaomin, Pang; Xiaotao, Wang; Wei, Dai; Jianyin, Hu; Ercang, Luo

    2017-02-01

    High efficiency cryocoolers working below 10 K have many applications such as cryo-pump, superconductor cooling and cryogenic electronics. This paper presents a thermally coupled two-stage pulse tube cryocooler system and its numeric analysis. The simulation results indicate that temperature distribution in the pulse tube has a significant impact on the system performance. So a precooling heat exchanger is put inside the second stage pulse tube for a deep investigation on its influence on the system performance. The influences of operating parameters such as precooling temperature, location of the precooling heat exchanger are discussed. Comparison of energy losses apparently show the advantages of the configuration which leads to an improvement on the efficiency. Finally, the cryocooler is predicted to be able to reach a relative Carnot efficiency of 10.7% at 10 K temperature.

  6. Development of a long pulse plasma gun discharge for magnetic turbulence studies

    Science.gov (United States)

    Schaffner, David

    2016-10-01

    A long pulse ( 300 μs) plasma gun discharge is in development at the Bryn Mawr College Plasma Laboratory for the production of sustained magnetized plasma injection for magnetohydrodynamic (MHD) turbulence studies. An array of eight 0.5mF parallel capacitors are used to create a pulse-forming-network (PFN) with a plateaued current output of 50kA for at least 200 of the 300 μs pulse. A 24cm inner diameter plasma gun provides stuffing flux fields at the stuffing threshold in order to allow for the continuous injection of magnetic helicity. Plasma is injected into a 24cm diameter flux-conserving aluminum chamber with a high density port array for fine spatial resolution diagnostic access. Fluctuations of magnetic field and saturation current are measured using pickup probes and Langmuir probes respectively.

  7. Study on a pulse tube cryocooler using gas mixture as its working fluid

    Science.gov (United States)

    Gao, C. M.; He, Y. L.; Chen, Z. Q.

    2000-01-01

    In order to improve the performance of a one-stage pulse tube cryocooler, gas mixtures are used for comparison, which have been used in other cryocoolers. A mixture of hydrogen and helium was investigated in this study. When the structure of the pulse tube is the same as mentioned in [C. Wang, P.Y. Wu, Zh.Q. Chen, Numerical modeling of an orifice pulse tube cryocooler, Cryogenics 32 (1992) 785] and the working conditions are: frequency 15 Hz, average pressure 1.1 MPa, hot end temperature 300 K and cold end temperature 80 K, it has been found that there are optimal molar percentage for the maximal cooling power and the maximal-coefficient of performance (COP) of this cryocooler.

  8. Time-resolved studies of the interactions between pulsed lasers and aerosols.

    Science.gov (United States)

    DeForest, Cindy L; Qian, Jun; Miller, Roger E

    2002-09-20

    Studies of the interaction between a pulsed CO2 laser and micrometer-sized aqueous and organic particles by use of light-scattering methods and step-scan Fourier-transform infrared (FTIR) spectroscopy are reported. Visible two-color extinction experiments indicate primary particle shattering, accompanied by a high fraction of vaporization, followed by secondary particle evaporation. The extent of the latter depends on the pulse intensity and particle composition. Angle-resolved light-scattering investigations provide insight into the aerosol size distribution and temperature following the pulsed heating event. The time dependence of the vapor plume, monitored with step-scan FTIR spectroscopy, confirms that a large fraction of the initial particle is quickly evaporated during the shattering event, followed by secondary fragment evaporation and thermal expansion.

  9. Nonlinear optical studies in semiconductor-doped glasses under femtosecond pulse excitation

    Indian Academy of Sciences (India)

    C P Singh; K S Bindra; S M Oak

    2010-12-01

    Nonlinear optical studies in semiconductor-doped glasses (SDGs) are performed under femtosecond laser pulse excitation. Z-scan experiments with 800 nm wave- length pulses are used to excite SDG samples in the resonance and non-resonance regimes. Schott colour glass filter OG 515 shows stronger two-photon absorption than GG 420 and both the samples exhibit positive nonlinearity. However, in resonantly excited RG 850 the intensity-dependent Z-scan shows transition from saturable to reverse saturable absorption behaviour with the increase in intensity.

  10. Comparative Study of Different Pulse Artifact Correction Techniques during Concurrent EEG-FMRI using FMRIB

    Directory of Open Access Journals (Sweden)

    Md Belayat Hossain

    2016-08-01

    Full Text Available In this work, a comparative study of three pulse artifact (PA correction methods –optimal basis set (OBS, simple mean (AAS and Gaussian-weighted mean (GWM – along with standard parameters setting for both gradient artefact (GA and pulse artefact (PA correction, using open source Functional MRI of Brain (FMRIB tool-box, in combined EEG-fMRI, is reported. It has been found that, of these three methods, OBS is better in preserving bio-signal while removing PA successfully.

  11. Voltammetric study of ketorolac and its differential pulse polarographic determination in pharmaceuticals.

    Science.gov (United States)

    Sturm, J C; Canelo, H; Nuñez-Vergara, L J; Squella, J A

    1997-05-01

    A differential pulse polarographic method for the quantitative determination of ketorolac is described. Ketorolac is an antiinflamatory-analgesic agent that is directly electroreducible at the mercury electrode. The polarographic reduction is due to the reduction of the benzoyl moiety in the ketorolac molecule. For analytical purposes, a very well resolved diffusion controlled differential pulse polarographic peak obtained at pH 9 was selected. This peak was used to develop a new method for the determination of ketorolac in pharmaceutical dosage forms. Recovery study shows that the method is sufficiently accurate and precise to be applied in the individual tablet assay of commercial samples.

  12. Radiolytic reactions of nitro blue tetrazolium under oxidative and reductive conditions: a pulse radiolysis study

    Science.gov (United States)

    Kovacs, A.; Wojnarovits, L.; Baranyai, M.; Moussa, A.; Othman, I.; McLaughlin, W. L.

    1999-08-01

    The radiolytic reactions of the ditetrazolium salt nitro blue tetrazolium chloride (NBTCl 2) were studied by pulse radiolysis technique in aqueous solution under reducing and oxidising conditions with the aim of potential dosimetry application. Under reducing conditions the fast formation of the tetrazolinyl radical is observed that is followed by the appearance of monoformazan (MF +), i.e. one of the tetrazolium rings is reduced to formazan. The formation of the water-insoluble diformazan, i.e. the result of the second reduction step was not observed in pulse radiolysis. Formazan formation was not found under oxidative conditions.

  13. Collisionless expansion of pulsed radio frequency plasmas. II. Parameter study

    Science.gov (United States)

    Schröder, T.; Grulke, O.; Klinger, T.; Boswell, R. W.; Charles, C.

    2016-01-01

    The plasma parameter dependencies of the dynamics during the expansion of plasma are studied with the use of a versatile particle-in-cell simulation tailored to a plasma expansion experiment [Schröder et al., J. Phys. D: Appl. Phys. 47, 055207 (2014); Schröder et al., Phys. Plasmas 23, 013511 (2016)]. The plasma expansion into a low-density ambient plasma features a propagating ion front that is preceding a density plateau. It has been shown that the front formation is entangled with a wave-breaking mechanism, i.e., an ion collapse [Sack and Schamel, Plasma Phys. Controlled Fusion 27, 717 (1985); Sack and Schamel, Phys. Lett. A 110, 206 (1985)], and the launch of an ion burst [Schröder et al., Phys. Plasmas 23, 013511 (2016)]. The systematic parameter study presented in this paper focuses on the influence on this mechanism its effect on the maximum velocity of the ion front and burst. It is shown that, apart from the well known dependency of the front propagation on the ion sound velocity, it also depends sensitively on the density ratio between main and ambient plasma density. The maximum ion velocity depends further on the initial potential gradient, being mostly influenced by the plasma density ratio in the source and expansion regions. The results of the study are compared with independent numerical studies.

  14. Flow Reactor Studies with Nanosecond Pulsed Discharges at Atmospheric Pressure and Higher

    Science.gov (United States)

    2013-10-01

    Image of Discharge Reactor with Viewport Inlet Cap • Modular plasma discharge reactor can be interchanged with redesigned pressure shell to perform...Flow Reactor Studies with Nanosecond Pulsed Discharges at Atmospheric Pressure and Higher Nicholas Tsolas, Kuni Togai and Richard Yetter...Department of Mechanical and Nuclear Engineering The Pennsylvania State University University Park, PA, 16801 Fourth Annual Review Meeting of the

  15. Feasibility of pulse oximetry in the initial prehospital management of victims of drowning : A preliminary study

    NARCIS (Netherlands)

    Montenij, Leonard J.; de Vries, Wiebe; Schwarte, Lothar; Bierens, Joost J. L. M.

    2011-01-01

    Aim: Immediate delivery of oxygen is the most important treatment for victims of drowning at the rescue site. Monitoring oxygen saturation with pulse oximetry is potentially useful, but its use may be limited by poor peripheral perfusion due to hypothermia. This preliminary study explores the feasib

  16. Relaxation and crystallization of amorphous carbamazepine studied by terahertz pulsed spectroscopy

    DEFF Research Database (Denmark)

    Zeitler, J Axel; Taday, Philip F; Pepper, Michael;

    2007-01-01

    At the example of carbamazepine the crystallization of a small organic molecule from its amorphous phase was studied using in situ variable temperature terahertz pulsed spectroscopy (TPS). Even though terahertz spectra of disordered materials in the glassy state exhibit no distinct spectral featu...

  17. Optimisation study of the synthesis of vanadium oxide nanostructures using pulsed laser deposition

    CSIR Research Space (South Africa)

    Masina, BN

    2014-02-01

    Full Text Available Fast imaging plasma plume study have been carried out on vanadium-oxygen plasma generated using 248 nm, 25 ns pulses from an excimer KrF laser under oxygen atmosphere. The plume expansion dynamics of an ablated VO(sub2) target was investigated using...

  18. Searches for Radio Pulsars & Fast Transients and Multiwavelength Studies of Single-pulse Emission

    Science.gov (United States)

    Mickaliger, Mitchell B.

    Pulsars are excellent tools for studying a wide array of astrophysical phenomena (e.g. gravitational waves, the interstellar medium, general relativity), yet they are still not fully understood. What are their emission processes and how do they change at different energies? How is giant pulse emission different from regular emission? How are different classes of pulsars (RRATs, magnetars, nulling pulsars, etc.) related? Answering these questions will not only help us to understand pulsars in general, but will also help improve techniques for pulsar searches and timing, gravitational wave searches, and single-pulse searches. The work we present here aims to answer these questions through studies of giant pulse emission, the discovery of new pulsars, and single-pulse studies of a large population of pulsars and RRATs. We took advantage of open telescope time on the 43-m telescope in Green Bank, WV to conduct a long-term study of giant pulses from the Crab pulsar at 1.2 GHz and 330 MHz. Over a timespan of 15 months, we collected a total of 95000 giant pulses which we correlated with both gamma-ray photons from the Fermi satellite and giant pulses collected at 8.9 GHz. Statistics of these pulses show that their amplitudes follow power-law distributions, with indices in the range of 2.1 to 3.1. The correlation with giant pulses at 8.9 GHz showed that the emission processes at 1.2 GHz and 8.9 GHz are related, despite significant profile differences. The correlation with Fermi gamma-ray photons was to test if increased pair production in the magnetosphere was the cause of giant pulses. Our findings suggest that, while it may play a role, increased pair production is not the dominant cause of giant pulses. As part of a single-pulse study, we reprocessed the archival Parkes Multibeam Pulsar Survey, discovering six previously unknown pulsars. PSR J0922-52 has a period of 9.68 ms and a DM of 122.4 pc cm-3. PSR J1147-66 has a period of 3.72 ms and a DM of 133.8 pc cm-3. PSR J

  19. Transient optical gratings for pulsed ionizing radiation studies

    CERN Document Server

    Fullagar, Wilfred K; Hall, Chris J

    2011-01-01

    Prior to the invention of holography or lasers, Bragg's X-ray microscope opened the door to optical computation in short-wavelength studies using spatially coherent visible light, including phase retrieval methods. This optical approach lost ground to semiconductor detection and digital computing in the 1960s. Since then, visible optics including spatial light modulators (SLMs), array detectors and femtosecond lasers have become widely available, routinely allowing versatile and computer-interfaced imposition of optical phase, molecular coherent control, and detection. Today, high brilliance X-ray sources begin to offer opportunities for atomic resolution and ultrafast pump-probe studies. Correspondingly, this work considers an overlooked aspect of Bragg's X-ray microscope - the incoherent ionizing radiation to coherent visible (IICV) conversion that is a necessary prerequisite for coherent optical computations. Technologies are suggested that can accomplish this conversion. Approaches to holographic data sto...

  20. Study of relationship between pulse pressure and mortality from all the causes, CVD and CVA

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Objective: To determine the relationship between pulse pressure and mortality from all the causes: CVD and CVA. Methods: The cohort consisted of the beneficiaries from Korea Medical Insurance Corporation (KMIC) aged 40 and older who had taken health examination and completed the questionnaire inquiring of health habits and past medical history in 1992 or 1993. The number of cohort members was 698,796, and they were followed up from 1st January, 1994 until 31st December, 2000. The primary sources of the data used in this study were the death benefit record and health examination file of KMIC. In the case that the information about the cause of death was unknown in the death benefit record, it was checked from the death registry of National statistical Office and the inpatient data of KMIC. There were 37439 deaths during the follow-up period. Results: A linear relationship between pulse pressure and mortality from all the causes, cardiovascular disease and cerebrovascular disease, was determined in both genders, the whole population and age groups, in the hypertensive and normotensive ( P< 0. 01). Pulse pressure and mortality from all the causes, CVD and CVA increased ( P <0.01). Pulse pressure was significantly associated with a relatively high risk of mortality from all the causes, CVD and CVA in the whole population, both genders, all age groups, the hypertensive and normotensive after adjusted to age, gender, body mass index, blood sugar, serum total cholesterol, AST, ALT, urine protein, urine glucose, alcohol drinking and cigarette smoking ( P< 0.01). Conclusion: Pulse pressure shows linear relationship with the mortality from all the causes,CVD and CVA. Pulse pressure appears to be a single measure of blood pressure in predicting mortality from all the causes,CVD and CVA, even in the hypertensive and normotensive.

  1. A nanosecond pulsed laser heating system for studying liquid and supercooled liquid films in ultrahigh vacuum.

    Science.gov (United States)

    Xu, Yuntao; Dibble, Collin J; Petrik, Nikolay G; Smith, R Scott; Joly, Alan G; Tonkyn, Russell G; Kay, Bruce D; Kimmel, Greg A

    2016-04-28

    A pulsed laser heating system has been developed that enables investigations of the dynamics and kinetics of nanoscale liquid films and liquid/solid interfaces on the nanosecond time scale in ultrahigh vacuum (UHV). Details of the design, implementation, and characterization of a nanosecond pulsed laser system for transiently heating nanoscale films are described. Nanosecond pulses from a Nd:YAG laser are used to rapidly heat thin films of adsorbed water or other volatile materials on a clean, well-characterized Pt(111) crystal in UHV. Heating rates of ∼10(10) K/s for temperature increases of ∼100-200 K are obtained. Subsequent rapid cooling (∼5 × 10(9) K/s) quenches the film, permitting in-situ, post-heating analysis using a variety of surface science techniques. Lateral variations in the laser pulse energy are ∼±2.7% leading to a temperature uncertainty of ∼±4.4 K for a temperature jump of 200 K. Initial experiments with the apparatus demonstrate that crystalline ice films initially held at 90 K can be rapidly transformed into liquid water films with T > 273 K. No discernable recrystallization occurs during the rapid cooling back to cryogenic temperatures. In contrast, amorphous solid water films heated below the melting point rapidly crystallize. The nanosecond pulsed laser heating system can prepare nanoscale liquid and supercooled liquid films that persist for nanoseconds per heat pulse in an UHV environment, enabling experimental studies of a wide range of phenomena in liquids and at liquid/solid interfaces.

  2. A nanosecond pulsed laser heating system for studying liquid and supercooled liquid films in ultrahigh vacuum

    Science.gov (United States)

    Xu, Yuntao; Dibble, Collin J.; Petrik, Nikolay G.; Smith, R. Scott; Joly, Alan G.; Tonkyn, Russell G.; Kay, Bruce D.; Kimmel, Greg A.

    2016-04-01

    A pulsed laser heating system has been developed that enables investigations of the dynamics and kinetics of nanoscale liquid films and liquid/solid interfaces on the nanosecond time scale in ultrahigh vacuum (UHV). Details of the design, implementation, and characterization of a nanosecond pulsed laser system for transiently heating nanoscale films are described. Nanosecond pulses from a Nd:YAG laser are used to rapidly heat thin films of adsorbed water or other volatile materials on a clean, well-characterized Pt(111) crystal in UHV. Heating rates of ˜1010 K/s for temperature increases of ˜100-200 K are obtained. Subsequent rapid cooling (˜5 × 109 K/s) quenches the film, permitting in-situ, post-heating analysis using a variety of surface science techniques. Lateral variations in the laser pulse energy are ˜±2.7% leading to a temperature uncertainty of ˜±4.4 K for a temperature jump of 200 K. Initial experiments with the apparatus demonstrate that crystalline ice films initially held at 90 K can be rapidly transformed into liquid water films with T > 273 K. No discernable recrystallization occurs during the rapid cooling back to cryogenic temperatures. In contrast, amorphous solid water films heated below the melting point rapidly crystallize. The nanosecond pulsed laser heating system can prepare nanoscale liquid and supercooled liquid films that persist for nanoseconds per heat pulse in an UHV environment, enabling experimental studies of a wide range of phenomena in liquids and at liquid/solid interfaces.

  3. Pulse on Pulse

    DEFF Research Database (Denmark)

    Schmidt, Ulrik; Carlson, Merete

    2012-01-01

    and pulsating ‘room’. Hence, the visitors in Pulse Room are invited into a complex scenario that continuously oscillates between various aspects of signification (the light bulbs representing individual lives; the pulse itself as the symbolic ‘rhythm of life’) and instants of pure material processuality......“Pulse on Pulse” investigates the relation between signifying processes and non-signifying material dynamism in the installation Pulse Room (2006-) by Mexican Canadian artist Rafael Lozano-Hemmer. In Pulse Room the sense of pulse is ambiguous. Biorhythms are transmitted from the pulsing energy...... of the visitor’s beating heart to the blink of a fragile light bulb, thereby transforming each light bulb into a register of individual life. But at the same time the blinking light bulbs together produce a chaotically flickering light environment composed by various layers of repetitive rhythms, a vibrant...

  4. Performance Evaluation of New-Generation Pulse Oximeters in the NICU: Observational Study.

    Science.gov (United States)

    Nizami, Shermeen; Greenwood, Kim; Barrowman, Nick; Harrold, JoAnn

    2015-09-01

    This crossover observational study compares the data characteristics and performance of new-generation Nellcor OXIMAX and Masimo SET SmartPod pulse oximeter technologies. The study was conducted independent of either original equipment manufacturer (OEM) across eleven preterm infants in a Neonatal Intensive Care Unit (NICU). The SmartPods were integrated with Dräger Infinity Delta monitors. The Delta monitor measured the heart rate (HR) using an independent electrocardiogram sensor, and the two SmartPods collected arterial oxygen saturation (SpO2) and pulse rate (PR). All patient data were non-Gaussian. Nellcor PR showed a higher correlation with the HR as compared to Masimo PR. The statistically significant difference found in their median values (1% for SpO2, 1 bpm for PR) was deemed clinically insignificant. SpO2 alarms generated by both SmartPods were observed and categorized for performance evaluation. Results for sensitivity, positive predictive value, accuracy and false alarm rates were Nellcor (80.3, 50, 44.5, 50%) and Masimo (72.2, 48.2, 40.6, 51.8%) respectively. These metrics were not statistically significantly different between the two pulse oximeters. Despite claims by OEMs, both pulse oximeters exhibited high false alarm rates, with no statistically or clinically significant difference in performance. These findings have a direct impact on alarm fatigue in the NICU. Performance evaluation studies can also impact medical device purchase decisions made by hospital administrators.

  5. Study on the dynamic holdup distribution of the pulsed extraction column

    Energy Technology Data Exchange (ETDEWEB)

    Wang, S.; Chen, J.; Wu, Q. [Tsinghua University, Beijing 100084 (China)

    2013-07-01

    In the study, a CSTR cascade dynamic hydraulic model was developed to investigate the dynamic holdup distribution of the pulsed extraction column. It is assumed that the dynamic process of the dispersed phase holdup of pulsed extraction column has equal effects with the operational process of multiple cascade CSTRs. The process is consistent with the following assumptions: the holdups vary on different stages but maintain uniform on each stage; the changes of the hydraulic parameters have impact initially on the inlet of dispersed phase, and stability will be reached gradually through stage-by-stage blending. The model was tested and verified utilizing time domain response curves of the average holdup. Nearly 150 experiments were carried out with different capillary columns, various feed liquids, and diverse continuous phases and under different operation conditions. The regression curves developed by the model show a good consistency with the experimental results. After linking parameters of the model with operational conditions, the study further found that the parameters are only linearly correlated with pulse conditions and have nothing to do with flow rate for a specific pulsed extraction column. The accuracy of the model is measured by the average holdup, and the absolute error is ±0.01. The model can provide supports for the boundary studies on hydraulics and mass transfer by making simple and reliable prediction of the dynamic holdup distribution, with relatively less accessible hydraulic experimental data. (authors)

  6. In vivo study of human skin using pulsed terahertz radiation

    Energy Technology Data Exchange (ETDEWEB)

    Pickwell, E [Semiconductor Physics Group, Cavendish Laboratory, Cambridge University, Madingley Road, Cambridge CB3 0HE (United Kingdom); Cole, B E [TeraView Ltd, Unit 302/4 Cambridge Science Park, Cambridge CB4 0WG (United Kingdom); Fitzgerald, A J [TeraView Ltd, Unit 302/4 Cambridge Science Park, Cambridge CB4 0WG (United Kingdom); Pepper, M [Semiconductor Physics Group, Cavendish Laboratory, Cambridge University, Madingley Road, Cambridge CB3 0HE (United Kingdom); Wallace, V P [TeraView Ltd, Unit 302/4 Cambridge Science Park, Cambridge CB4 0WG (United Kingdom)

    2004-05-07

    Studies in terahertz (THz) imaging have revealed a significant difference between skin cancer (basal cell carcinoma) and healthy tissue. Since water has strong absorptions at THz frequencies and tumours tend to have different water content from normal tissue, a likely contrast mechanism is variation in water content. Thus, we have previously devised a finite difference time-domain (FDTD) model which is able to closely simulate the interaction of THz radiation with water. In this work we investigate the interaction of THz radiation with normal human skin on the forearm and palm of the hand in vivo. We conduct the first ever systematic in vivo study of the response of THz radiation to normal skin. We take in vivo reflection measurements of normal skin on the forearm and palm of the hand of 20 volunteers. We compare individual examples of THz responses with the mean response for the areas of skin under investigation. Using the in vivo data, we demonstrate that the FDTD model can be applied to biological tissue. In particular, we successfully simulate the interaction of THz radiation with the volar forearm. Understanding the interaction of THz radiation with normal skin will form a step towards developing improved imaging algorithms for diagnostic detection of skin cancer and other tissue disorders using THz radiation.

  7. A Tapered Chalcogenide Microstructured Optical Fiber for Mid-IR Parabolic Pulse Generation: Design and Performance Study

    CERN Document Server

    Barh, Ajanta; Varshney, Ravi K; Pal, Bishnu P

    2013-01-01

    This paper presents a theoretical design of chalcogenide glass based tapered microstructured optical fiber (MOF) to generate high power parabolic pulses (PPs) at the mid-IR wavelength (~ 2 {\\mu}m). We optimize fiber cross-section by the multipole method and studied pulse evolution by well known Symmetrized Split-Step Fourier Method. Our numerical investigation reveals the possibility of highly efficient PP generation within a very short length (~ 18 cm) of this MOF for a Gaussian input pulse of 60 W peak power and FWHM of 3.5 ps. We examined quality of the generated PP by calculating the misfit parameter including the third order dispersion and fiber loss. Further, the effects of variations in input pulse power, pulse width and pulse energy on generated PP were also studied.

  8. An Optimization of Pulsed ElectroMagnetic Fields Study

    Science.gov (United States)

    Goodwin, Thomas J.

    2006-01-01

    To date, in our research we have focused on the use of normal human neuronal progenitor (NHNP) cells because of their importance in human nervous system regeneration, development and maintenance, but we have developed 2-D and 3-D bioreactors that can accommodate any cell line. In this Project, we will include the use of tissues important for physiological regeneration: Human osteoblasts or chondrocytes, and vascular cells. Our initial results with the NHNP cells were quite startling using extremely low-level electromagnetic fields (5 microtesla at 10Hz; 6mA). The low-amplitude, rapidly time-varying electromagnetic fields exert a very potent effect on the proliferation, morphology, and gene expression of the cells in culture, both in standard 2-dimensional culture plates as well as cells organized into 3-dimensional tissue-like assemblies (TLAs) in a 3D bioreactor. We have replicated our preliminary results many, many times, have analyzed the gene expression using gene arrays (followed by Luminex analysis for protein production), and have monitored cell proliferation, orientation, morphology, and glucose metabolism, and we are confident that we have a stable and reliable model to study the control of high-level cellular processes by application of low-amplitude, time varying electromagnetic fields (TVEMF) (1, 2). In additional studies at the University of Michigan, we have been able to generate functional in vitro engineered mammalian skeletal muscle, and have employed nerve-muscle co-culture techniques to promote axonal sprouting. We believe that nearly all tissues, in particular, neural, are susceptible to the influences of low-level TVEMF.

  9. Pulsed NMR studies of water under extreme conditions

    Energy Technology Data Exchange (ETDEWEB)

    DeFries, Timothy Hatmaker

    1978-01-01

    The dynamic structure of water and heavy water was studied using NMR spin-lattice relaxation and self-diffusion techniques. For both compounds, the relaxation rate is proportional to the ratio of viscosity to absolute temperature at constant density. The coupling between rotational and translational motions decreases with increasing temperature and increasing density. The temperature and density dependence of the deuteron quadrupole coupling constant in D/sub 2/O was determined. The proton spin-lattice relaxation times of supercritical H/sub 2/O were measured from 400 to 700/sup 0/C and to 1 kbar. The times were found to be roughly proportional to density and were found to decrease with temperature. The angular momentum correlation times tau/sub J/ were calculated and compared with the times between collisions for a hard sphere fluid, the Enskog times, tau/sub E/. The values of tau/sub E//tau/sub J/ were roughly 6 at 400/sup 0/C and low densities. The values decreased at higher densities and higher temperatures. The proton spin-lattice relaxation times of H/sub 2/O were also measured from 90 to 350/sup 0/C up to 2 to 5 kbar. The data clearly show the change from dipolar to spin-rotation relaxation as a function of temperature and density. Both the low and the high temperature results agree with the idea that it is the strong and anisotropic intermolecular potential which causes the dynamic behavior of water to be so different from that of normal liquids.

  10. Redox chemistry of - and -hydroxycinnamic acids: A pulse radiolysis study

    Indian Academy of Sciences (India)

    P Yadav; H Mohan; B S M Rao; J P Mittal

    2002-12-01

    Radiation chemical reactions of ${}^{\\bullet}$OH, O$^{\\bullet -}$, N$_{3}^{\\bullet}$ and $e^{-}_{aq}$ with - and -hydroxycinnamic acids were studied. The second-order rate constants for the reaction of ${}^{\\bullet}$OH with ortho and meta isomers in buffer solution at H 7 are 3.9 ± 0.2 × 109 and 4.4 ± 0.3 × 109 dm3 mol-1 s-1 respectively. At H 3 the rate with the ortho isomer was halved (1.6 ± 0.4 × 109 dm3 mol-1 s-1) but it was unaffected in the case of meta isomer ( = 4.2 ± 0.6 × 109 dm3 mol-1 s-1). The rate constant in the reaction of N$_{3}^{\\bullet}$ with the ortho isomer is lower by an order of magnitude ( = 4.9 ± 0.4 × 108 dm3 mol-1s-1). The rates of the reaction of $e^{-}_{aq}$ with ortho and meta isomers were found to be diffusion controlled. The transient absorption spectrum measured in the ${}^{\\bullet}$OH with -hydroxycinnamic acid exhibited an absorption maximum at 360 nm and in meta isomer the spectrum was blue-shifted (330 nm) with a shoulder at 390 nm. A peak at 420 nm was observed in the reaction of O$^{\\bullet-}$ with the -isomer whereas the meta isomer has a maximum at 390 and a broad shoulder at 450 nm. In the reaction of $e^{-}_{aq}$, the absorption peaks were centred at 370-380 nm in both the isomers. The underlying reaction mechanism is discussed.

  11. Study of Cellular Experiment of Electric Pulse Imposed on Cancer Cell

    Institute of Scientific and Technical Information of China (English)

    XIONGLan; HUYa; 等

    2002-01-01

    The objective of the study is the cytocidal and inhibitory effect of energy-controllable pulse on ovarian cancer cell line SKOV3.Ovarian cancer cell suspension were treated by electric pulse with different parameters,.The inhibitory rate(IR) was assayed by modified colorimetric MTT methods,the growth curves of two test groups and one control group were also measured.and the ultrasturctureal changes were observed under electron microscopy(EM) and scan electron microscopy (SEM),It was found that the treated SKOV3 cell proliferated more slowly.IR was increased with the enhancement of pulse paramters,The ultrastructural study showed that morphological changes occured obviously.Swollen mitochondria,fracutured ridges,cytoplasmic vacuoles and membrane holes appeard in most of the processed cells,and a part of bilayer membrane was ruptured.It is indicated that irreversible electric breakdown occurred in some of the treated cells,and the electric pulse could kill cancer cell and inhibit its recovery and growth.

  12. Study on weld pool behaviors and ripple formation in dissimilar welding under pulsed laser

    Science.gov (United States)

    Liang, Rong; Luo, Yu

    2017-08-01

    A three-transient numerical model is developed to study the dissimilar metal welding under pulsed laser. The melting, resolidification and vaporization inducing recoil pressure are considered in this model. Their effects on molten pool dynamic and the weld bead formation are studied. The similar metal welding and dissimilar metal welding under pulsed laser are respectively simulated by using this model. It is found that surface ripples are caused mainly by the periodical laser and molten pool solidification. In the first, this model is validated by the weld bead geometry comparison between the simulated and experimental results in similar metal welding. Then, this model is applied to simulate the dissimilar metal welding under pulsed laser. The results show that the distributions of the temperature, melt-flow velocity and surface ripples are asymmetric due to the differences in physical properties of the materials. The higher pulse overlapping factor decreases the solidification rate, leading to the more uniform penetration depths and the finer ripples. Good agreements between the experimental observations and simulation results are obtained by the proposed model.

  13. A study on Al2O3 passivation in GaN MOS-HEMT by pulsed stress

    Institute of Scientific and Technical Information of China (English)

    Yue Yuan-Zheng; Hao Yue; Zhang Jin-Cheng; Feng Qian; Ni Jin-Yu; Ma Xiao-Hua

    2008-01-01

    This paper studies systematically the drain current collapse in AlGaN/GaN metal-oxide-semiconductor high electron mobility transistors (MOS-HEMTs) by applying pulsed stress to the device. Low-temperature layer of Al2O3 ultrathin film used as both gate dielectric and surface paasivation layer was deposited by atomic layer deposition (ALD).For HEMT, gate turn-on pulses induced large current collapse. However, for MOS-HEMT, no significant current collapse was found in the gate turn-on pulsing mode with different pulse widths, indicating the good passivation effect of ALD Al2O3. A small increase in Id in the drain pulsing mode is due to the relieving of self-heating effect. The comparison of synchronously dynamic pulsed Id - Vds characteristics of HEMT and MOS-HEMT further demonstrated the good passivation effect of ALD Al2O3.

  14. A Clinical Study of the Pulse Wave Characteristics at the Three Pulse Diagnosis Positions of Chon, Gwan and Cheok

    Directory of Open Access Journals (Sweden)

    Young J. Jeon

    2011-01-01

    Full Text Available In this work, we analyze the baseline, signal strength, aortic augmentation index (AIx, radial AIx, time to reflection and P_T2 at Chon, Gwan, and Cheok, which are the three pulse diagnosis positions in Oriental medicine. For the pulse measurement, we used the SphygmoCor apparatus, which has been widely used for the evaluation of the arterial stiffness at the aorta. By two-way repeated measures analysis of variance, we tested two independent measurements for repeatability and investigated their mean differences among Chon, Gwan and Cheok. To characterize further the parameters that were shown to be different between each palpation position, we carried out Duncan's test for the multiple comparisons. The baseline and signal strength were statistically different (<.05 among Chon, Gwan and Cheok, respectively, which supports the major hypothesis of Oriental medicine that all of the three palpation positions contain different clinical information. On the other hand, aortic AIx and time to reflection were found to be statistically different between Chon and the others, and radial AIx and P_T2 did not show any difference between pulse positions. In the clinical sense, however, the aortic AIx at each palpation position was found to fall within the 90% confidence interval of normal arterial compliance. The results of the multiple comparisons indicate that the parameters of arterial stiffness were independent of the palpation positions. This work is the first attempt to characterize quantitatively the pulse signals at Chon, Gwan and Cheok with some relevant parameters extracted from the SphygmoCor apparatus.

  15. Experimental Study on Bubble Pulse Features Under the Combined Action of Horizontal and Vertical Walls

    Institute of Scientific and Technical Information of China (English)

    王诗平; 初文华; 张阿漫

    2014-01-01

    The pulse features of a bubble have a close connection with the boundary condition. When a bubble moves near a rigid wall, it will be attracted by the Bjerknes force of the wall, and a jet pointing at the wall will be generated. In real application, the bubble may move under the combined action of walls in different directions when it forms at the corner of a pipe or at the bottom of a dam. The motion of the bubble shows complex and nonlinear characteristics under these conditions. In order to investigate the bubble pulse features near complex walls, a horizontal wall and a vertical wall are put into the experimental water tank synchronously, and an electric circuit with 200 voltages is designed to generate discharge bubbles, and then experimental study on the bubble pulse features under the combined action of horizontal and vertical walls is carried out. The influences of the combined action of two walls on the bubble shape, pulse period, moving trace and inside jet are obtained by changing the distances from bubble center to the two walls. It aims at providing references for the relevant theoretical and numerical research.

  16. Study on mitigation of pulsed heat load for ITER cryogenic system

    Science.gov (United States)

    Peng, N.; Xiong, L. Y.; Jiang, Y. C.; Tang, J. C.; Liu, L. Q.

    2015-03-01

    One of the key requirements for ITER cryogenic system is the mitigation of the pulsed heat load deposited in the magnet system due to magnetic field variation and pulsed DT neutron production. As one of the control strategies, bypass valves of Toroidal Field (TF) case helium loop would be adjusted to mitigate the pulsed heat load to the LHe plant. A quasi-3D time-dependent thermal-hydraulic analysis of the TF winding packs and TF case has been performed to study the behaviors of TF magnets during the reference plasma scenario with the pulses of 400 s burn and repetition time of 1800 s. The model is based on a 1D helium flow and quasi-3D solid heat conduction model. The whole TF magnet is simulated taking into account thermal conduction between winding pack and case which are cooled separately. The heat loads are given as input information, which include AC losses in the conductor, eddy current losses in the structure, thermal radiation, thermal conduction and nuclear heating. The simulation results indicate that the temperature variation of TF magnet stays within the allowable range when the smooth control strategy is active.

  17. [Experimental study on activating antileukemic T cells by vaccination with dendritic cells pulsed with survivin].

    Science.gov (United States)

    Zhang, Xiao-Hui; Xia, Ling-Hui; Liu, Zhong-Ping; Wei, Wen-Ning; Hu, Yu; Song, Shan-Jun

    2003-02-01

    The objective of this study is to investigate the effect of vaccination with dendritic cells pulsed with survivin antigen on activation of antileukemic T cells, and inhibiting proliferation of leukemic cells. The expression of survivin on acute leukemic cells were detected by cofocal microscopy and immunoprecipitation-Western blot. DCs collected from peripheral blood mononuclear cells were pulsed with survivin purified proteins. Stimulation index (SI) and antileukemia CTL induction were analyzed with (3)H-TdR incorporation and (51)Cr releasing assay, respectively. The phenotype of T cells and DCs were identified by flow cytometry. By immunofluorescence of bone marrow and peripheral blood mononuclear cells, survivin expression was detected in 16 out of 19 AML cases (84.2%). The results showed that survivin fluorescence distribution was in cytoplasm. DCs from peripheral blood mononuclear cells were successfully induced, with typical DC morphologic characteristic. The vaccination with dendritic cells pulsed with survivin antigen dramatically stimulated the proliferation of T cells. The DCs loading survivin activated T cells with higher CD4(+) T(H) ratio as compared with DCs group, T cells activated with DCs expressed CD8 and CD56. Survivin DCs significantly inhibited the growth of leukemic cells in vitro. In conclusion, survivin antigen expressed in the cytoplasm of leukemic cells, leukemic vaccination with DCs pulsed with survivin antigen in vitro inhibited the proliferation of leukemic cells, that may be a pathway for therapy of leukemia.

  18. Pulse Intravenous Clomipramine as an alternative antidepressant treatment to ECT: A pilot study

    Directory of Open Access Journals (Sweden)

    Maj-Liz Persson

    2007-12-01

    Full Text Available Background and Objectives: The aim of the study was to examine the antidepressant effect of a single pulse dose of intravenous clomipramine (200 mg i.v. followed by oral administration as an alternative method to electroconvulsive therapy. Methods: Twenty-one inpatients (8 male, 13 female with major depression were included. Depression severity was measured by Montgomery Asberg Rating Scale (MADRS and Clinical Global Impression severity scale (CGI-S before the pulse dose and 1 week after. The day after the pulse dose, the patient was medicated with 75 mg of oral clomipramine and from day two with 150 mg clomipramine daily. Results: The MADRS score dropped with 39% ± 22% and the CGI score with 28% ± 19% in one week. The improvement of the MADRS score after one week was 13.1 (C.I.9.5-17.0. CGI-ratings dropped from a mean of 5.5 (SD 1.2 to 3.9 (SD 1.1, an improvement of 28% ± 19%.(C.I. 1.0-2.1. Both improvements were significant (p<000.1. Conclusions: Single pulse dose clomipramine administration ameliorates depressive symptoms, and may be an alternative to ECT.

  19. A Study of Multi-frequency Polarization Pulse Profiles of Millisecond Pulsars

    CERN Document Server

    Dai, S; Manchester, R N; Kerr, M; Shannon, R M; van Straten, W; Mata, A; Bailes, M; Bhat, N D R; Burke-Spolaor, S; Coles, W A; Johnston, S; Keith, M J; Levin, Y; Oslowski, S; Reardon, D; Ravi, V; Sarkissian, J M; Tiburzi, C; Toomey, L; Wang, H G; Wang, J -B; Wen, L; Xu, R X; Yan, W M; Zhu, X -J

    2015-01-01

    We present high signal-to-noise ratio, multi-frequency polarization pulse profiles for 24 millisecond pulsars that are being observed as part of the Parkes Pulsar Timing Array (PPTA) project. The pulsars are observed in three bands, centred close to 730, 1400 and 3100 MHz, using a dual-band 10 cm/50 cm receiver and the central beam of the 20 cm multibeam receiver. Observations spanning approximately six years have been carefully calibrated and summed to produce high S/N profiles. This allows us to study the individual profile components and in particular how they evolve with frequency. We also identify previously undetected profile features. For many pulsars we show that pulsed emission extends across almost the entire pulse profile. The pulse component widths and component separations follow a complex evolution with frequency; in some cases these parameters increase and in other cases they decrease with increasing frequency. The evolution with frequency of the polarization properties of the profile is also n...

  20. Distinguishing between similar tubular objects using pulse reflectometry: a study of trumpet and cornet leadpipes

    Science.gov (United States)

    Buick, J. M.; Kemp, J.; Sharp, D. B.; van Walstijn, M.; Campbell, D. M.; Smith, R. A.

    2002-05-01

    This paper considers the measurement of the internal radius of a number of similar, short, tubular leadpipes using pulse reflectometry. Pulse reflectometry is an acoustical technique for measuring the internal bore of a tubular object by analysing the reflections which occur when an acoustical pulse is directed into the object. The leadpipes are designed to form the initial, or lead, part of a trumpet or cornet and their internal radii differ by less than 0.1 mm between similar pipes. The ability of the reflectometer to detect these small differences, which are considered by players to produce a noticeable difference in the sound of an instrument, are investigated. It is seen that the pulse reflectometer is able to distinguish between leadpipes with different nominal radii varying by as little as 0.03 mm, demonstrating its potential in the study of musical instruments and showing that it can be used as a diagnostic tool by the instrument manufacturer to detect defects which are significant enough to acoustically alter performance. The absolute accuracy of the radius measurements is also considered at the end of the leadpipe, where the uncertainty is ±0.05 mm.

  1. Off-resonance effects in (14)N NQR signals from the pulsed spin-locking (PSL) and three-pulse echo sequence; a study for monoclinic TNT.

    Science.gov (United States)

    Smith, John A S; Rowe, Michael D; Althoefer, Kaspar; Peirson, Neil F; Barras, Jamie

    2015-10-01

    In NQR detection applications signal averaging by the summation of rapidly regenerated signals from multiple pulse sequences of the pulsed spin-locking (PSL) type is often used to improve sensitivity. It is important to characterise and if possible minimise PSL sequence off-resonance effects since they can make it difficult to optimise detection performance. We illustrate this with measurements of the variation of the decay time T2e and the amplitude of PSL signal trains with pulse spacing and excitation offset frequency for the 870 kHz ν+(14)N NQR line of monoclinic TNT under carefully stabilised temperature conditions. We have also carried out a similar study of signals from monoclinic TNT and 1H-1,2,3-triazole generated by a three-pulse echo sequence and the results are shown to agree well with a theoretical treatment appropriate to polycrystalline NQR samples such as TNT for which spin I=1, asymmetry parameter η≠0 and T1≫T2. Based on this theory we derive simple models for calculating TNT PSL signal trains and hence the pulse spacing and off-resonance dependence of signal amplitude and T2e which we compare to our experimental data. We discuss the influence of PSL echo summation on off-resonance effects in detected signal intensity and show how a phase-alternated multiple pulse sequence can be used in combination with the PSL sequence to eliminate variation in detection performance due to off-resonance effects.

  2. Ultrafast Internal Conversion of Aromatic Molecules Studied by Photoelectron Spectroscopy using Sub-20 fs Laser Pulses

    Directory of Open Access Journals (Sweden)

    Toshinori Suzuki

    2014-02-01

    Full Text Available This article describes our recent experimental studies on internal conversion via a conical intersection using photoelectron spectroscopy. Ultrafast S2(ππ*–S1(nπ* internal conversion in pyrazine is observed in real time using sub-20 fs deep ultraviolet pulses (264 and 198 nm. While the photoelectron kinetic energy distribution does not exhibit a clear signature of internal conversion, the photoelectron angular anisotropy unambiguously reveals the sudden change of electron configuration upon internal conversion. An explanation is presented as to why these two observables have different sensitivities to internal conversion. The 198 nm probe photon energy is insufficient for covering the entire Franck-Condon envelopes upon photoionization from S2/S1 to D1/D0. A vacuum ultraviolet free electron laser (SCSS producing 161 nm radiation is employed to solve this problem, while its pulse-to-pulse timing jitter limits the time resolution to about 1 ps. The S2–S1 internal conversion is revisited using the sub-20 fs 159 nm pulse created by filamentation four-wave mixing. Conical intersections between D1(π−1 and D0(n−1 and also between the Rydberg state with a D1 ion core and that with a D0 ion core of pyrazine are studied by He(I photoelectron spectroscopy, pulsed field ionization photoelectron spectroscopy and one-color resonance-enhanced multiphoton ionization spectroscopy. Finally, ultrafast S2(ππ*–S1(ππ* internal conversion in benzene and toluene are compared with pyrazine.

  3. Pulsed electrical discharges in water for removal of organic pollutants: a comparative study

    OpenAIRE

    Dang, T.H.; Denat, A.; Lesaint, O.; Teissedre, G.

    2009-01-01

    Abstract In this study, the efficiency of different types of pulsed electrical discharges for the removal of organic pollutants from wastewater has been determined. Three discharge types, either in the water volume or in close proximity to the water surface are studied. The production of hydrogen peroxide in pure water, and the degradation of two typical pollutants (4-chlorophenol and 4-nitrophenol) is measured together with the amount of electrical energy d...

  4. Pulse radiolytic studies of electron transfer processes and applications to solar photochemistry. Progress report

    Energy Technology Data Exchange (ETDEWEB)

    Neta, P.

    1995-02-01

    The pulse radiolysis technique is applied to the study of electron transfer processes in a variety of chemical systems. Reactive intermediates are produced in solution by electron pulse irradiation and the kinetics of their reactions are followed by time resolved absorption spectrophotometry. Complementary experiments are carried out with excimer laser flash photolysis. These studies are concerned with mechanisms, kinetics, and thermodynamics of reactions of organic and inorganic radicals and unstable oxidation states of metal ions. Reactions are studied in both aqueous and non-aqueous solutions. The studies focus on the unique ability of pulse radiolysis to provide absolute rate constants for reactions of many inorganic radicals and organic peroxyl radicals, species that are key intermediates in many chemical processes. A special concern of this work is the study of electron transfer reactions of metalloporphyrins, which permits evaluation of these molecules as intermediates in solar energy conversion. Metalloporphyrins react with free radicals via electron transfer, involving the ligand or the metal center, or via bonding to the metal, leading to a variety of chemical species whose behavior is also investigated. The highlights of the results during the past three years are summarized below under the following sections: (a) electron transfer reactions of peroxyl radicals, concentrating on the characterization of new peroxyl radicals derived from vinyl, phenyl, other aryl, and pyridyl; (b) solvent effects on electron transfer reactions of inorganic and organic peroxyl radicals, including reactions with porphyrins, and (c) electron transfer and alkylation reactions of metalloporphyrins and other complexes.

  5. Experimental Study of Diamond Like Carbon (DLC) Coated Electrodes for Pulsed High Gradient Electron Gun

    CERN Document Server

    Paraliev, M; Ivkovic, S; Le Pimpec, F

    2010-01-01

    For the SwissFEL Free Electron Laser project at the Paul Scherrer Institute, a pulsed High Gradient (HG) electron gun was used to study low emittance electron sources. Different metals and surface treatments for the cathode and anode were studied for their HG suitability. Diamond Like Carbon (DLC) coatings are found to perform exceptionally well for vacuum gap insulation. A set of DLC coated electrodes with different coating parameters were tested for both vacuum breakdown and photo electron emission. Surface electric fields over 250MV/m (350 - 400kV, pulsed) were achieved without breakdown. From the same surface, it was possible to photo-emit an electron beam at gradients up to 150MV/m. The test setup and the experimental results are presented

  6. Laser Induced Damage Studies in Borosilicate Glass Using nanosecond and sub nanosecond pulses

    CERN Document Server

    Rastogi, Vinay; Munda, D S

    2016-01-01

    The damage mechanism induced by laser pulse of different duration in borosilicate glass widely used for making confinement geometry targets which are important for laser driven shock multiplication and elongation of pressure pulse, is studied. We measured the front and rear surface damage threshold of borosilicate glass and their dependency on laser parameters. In this paper, we also study the thermal effects on the damage diameters, generated at the time of plasma formation. These induced damage width, geometries and microstructure changes are measured and analyzed with optical microscope, scanning electron microscope and Raman spectroscopy. The results show that at low energies symmetrical damages are found and these damage width increases nonlinearly with laser intensity. The emitted optical spectrum during the process of breakdown is also investigated and is used for the characterization of emitted plasma such as plasma temperature and free electron density. Optical emission lines from Si I at 500 nm, Si ...

  7. Differential pulse voltammetric studies on the effects of Al(Ⅲ) on the lactate dehydrogenase activity

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    In this paper, differential pulse voltammetry (DPV) was applied to study the effects of aluminum Al(Ⅲ) on the lactate dehydrogenase (LDH) activity. Michaelis-Menten constant (KNADHm) and maximum velocity (vmax) in the enzyme promoting catalytic reaction of "pyruvate(Pyr) + NADH + H+ LDH(=) lactate + NAD+" under different conditions by monitoring DPV reduction current of NAD+ were reported.(C) 2007 Shu Ping Bi. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

  8. Fundamental Study of Interactions Between High-Density Pulsed Plasmas and Materials for Space Propulsion

    Science.gov (United States)

    2012-09-01

    interactions studies (plasma too cold and too “dirty.”) We have built and tested a new, gas -fed, non- ablative, rep-rated capillary plasma source for our...those encountered in space propulsion devices including Pulsed Plasma Thrusters (PPT), Magneto-Plasma Dynamic (MPD) thrusters and capillary plasma...based thrusters . The ongoing research work brings together a team of researchers from the University of Texas at Austin (UT) and the University of

  9. Study on geminate ion recombination in liquid dodecane using pico- and subpicosecond pulse radiolysis

    Energy Technology Data Exchange (ETDEWEB)

    Saeki, Akinori E-mail: saeki03@sanken.osaka-u.ac.jp; Kozawa, Takahiro; Yoshida, Yoichi; Tagawa, Seiichi

    2001-07-01

    Geminate ion recombination was studied by the laser-synchronized pulse radiolysis system which was developed at Osaka University. The time-dependent behavior of the cation radicals in liquid n-dodecane on picosecond time scale showed a typical geminate decay. The experimental data were compared with the theoretical decay based on the diffusion theory with the convolution technique in the time region within 1 ns. (author)

  10. Density-Functional-Theory Studies of C20 in Femtosecond Laser Pulses

    Institute of Scientific and Technical Information of China (English)

    WANG Zhi-Ping; BIAN Bao-An; WANG Li-Guang

    2010-01-01

    @@ We study the electron response of C20 excited by strong femtosecond laser pulses by applying the time-dependent local-density approximation,an approach which has proven to provide a robust tool for investigations of fullerene.The optical response as well as the full electronic dipolar response and ionization processes of C20 subject to the laser field are explored.A strong correlation between induced electronic dipole oscillations and electron emission is observed.

  11. Study on the influence of laser pulse duration in the long nanosecond regime on the laser induced plasma spectroscopy

    Science.gov (United States)

    Elnasharty, I. Y.

    2016-10-01

    By using a high power pulsed fiber laser, this study reports the experimental investigation of the laser-induced plasma characteristics for the laser pulse duration range extended from 40 ns to 200 ns. The experiments were performed with keeping the laser fluence constant at 64 J/cm2. The measurements show that, for the early phase of plasma formation, the spectral line intensities and the continuum emissions as well as the plasma characteristics decay to a certain extent with the increase of the pulse duration. On the other hand, as the plasma evolves in post laser pulse regime, the electron density and the degree of ionization increase slightly for the longer pulses, while the plume temperature is more or less independent from the pulse duration. Furthermore, the ablation characteristics, such as the ablation rate, coincide with the results of plasma characteristics for the different pulse durations. Eventually, with keeping the laser fluence constant at 64 J/cm2, the analytical performance of Laser-Induced Plasma Spectroscopy (LIPS) for the corresponding pulse duration range is examined by using a temporal gating and non-gating analyses. The measurements show that, in the case of gating analysis, all pulse durations yield almost the same range of limits of detections LODs. On the other hand, for non-gating analysis, the longer pulse durations provide lower LODs (better) than the shorter ones by orders of magnitude. Moreover, the calculated absolute limit of detection (LODAbs) for the longest pulse duration (i.e. 200 ns) is lower by approximately factor 2 than that of the shortest one (i.e. 40 ns).

  12. Electron thermalization and attachment in pulse-irradiated oxygen studied by time-resolved microwave conductivity

    Science.gov (United States)

    Warman, John M.; Cooper, Ronald

    The microwave conductivity of oxygen gas following nanosecond pulsed irradiation has been studied for pressures from 5 to 50 torr. The conductivity is found to decrease by a factor of approx. 20 in the early stages ( tN < 2 x 10 11 s cm -3) following the pulse. This is attributed to a decrease in the electron collision frequency as the initial excess energy of the electrons becomes degraded. A further decrease found at longer times is due to the three-body attachment of electrons to O 2 with a rate constant of 2.4 x 10 -30 cm 6s -1. Above a pressure of approx. 30 torr significant attachment begins to occur while electrons are still superthermal. The time at which the microwave signal is within 10% of the value corresponding to thermal energies is given by τ thP ≈ 15 μs.torr.

  13. A comparative study of hair removal at an NHS hospital: Luminette intense pulsed light versus electrolysis.

    Science.gov (United States)

    Harris, Karen; Ferguson, Janice; Hills, Samantha

    2014-04-01

    Twenty-five women, referred for hair removal by electrolysis, were enrolled in a split face study to treat facial hirsutism. Each patient was treated on six occasions: one-half of the face with electrolysis and the other side with an intense pulsed light source. Patients were evaluated with respect to reduction in hair counts, side effects and discomfort during treatment. Re-growth was assessed at 3, 6 and 9 months following treatment. All patients, except one with very sparse, fair hair growth, preferred treatment with the Intense Pulsed Light and rated their average hair reduction with this method as 77% after five treatments. The overall patient satisfaction rates as determined by visual analogue scales were 8.3 out of 10 for IPL and 5.4 out of 10 for electrolysis.

  14. Study of pulse structure and radiative mechanisms associations of long GRBs at z~1

    Science.gov (United States)

    Quirola, Jonathan; Vásquez, Nicolás

    2015-03-01

    In this work, we have studied five different GRBs detected by Swift: GRB 071010B (z = 0.94), GRB 080411 (z = 1.03), GRB 080413B (z = 1.10), GRB 091208B (z = 1.06) and GRB 110715A (z = 0.82); Those GRBs, with similar z and have well defined pulses. To obtain spectral lag, we fit the light curves with a model having exponential rise and decay parts. In addition, we performed spectral analysis using three spectral models for different GRBs' regions: power law, cutoff power law and band model. Additionaly, we releated spectral parameters such as photon index and luminosity with spectral lag. The analysis suggests that there are two types of pulses associated to specific radiation mechanisms which would reveal the radiation process of long gamma-ray bursts.

  15. Simulation study of electron injection into plasma wake fields by colliding laser pulses using OOPIC

    Institute of Scientific and Technical Information of China (English)

    HE An; GAO Jie; ZHU Xiong-Wei; LI Da-Zhang; XU Hong-Liang

    2009-01-01

    An electron injector concept for a laser-plasma accelerator has been developed which relies on the use of counter propagating ultrashort laser pulses.In this paper,we use OOPIC the fully self-consistent,twodimensional.particle-in-cell code to make a parameter study to determine the bunches that can be obtained through collisions of two collinear laser pulses in uniform plasma.A series of simulations show that one can obtain a short(<10fs)bunch with its charge of about 15pC,and energy spread of about 15%.We also discussed the variation of the transverse spot size of the electron bunch and found the bunch would undergo the betatron oscillations.

  16. Biomolecular papain thin films grown by matrix assisted and conventional pulsed laser deposition: A comparative study

    Science.gov (United States)

    György, E.; Pérez del Pino, A.; Sauthier, G.; Figueras, A.

    2009-12-01

    Biomolecular papain thin films were grown both by matrix assisted pulsed laser evaporation (MAPLE) and conventional pulsed laser deposition (PLD) techniques with the aid of an UV KrF∗ (λ =248 nm, τFWHM≅20 ns) excimer laser source. For the MAPLE experiments the targets submitted to laser radiation consisted on frozen composites obtained by dissolving the biomaterial powder in distilled water at 10 wt % concentration. Conventional pressed biomaterial powder targets were used in the PLD experiments. The surface morphology of the obtained thin films was studied by atomic force microscopy and their structure and composition were investigated by Fourier transform infrared spectroscopy. The possible physical mechanisms implied in the ablation processes of the two techniques, under comparable experimental conditions were identified. The results showed that the growth mode, surface morphology as well as structure of the deposited biomaterial thin films are determined both by the incident laser fluence value as well as target preparation procedure.

  17. Studies on an improved indigenous pressure wave generator and its testing with a pulse tube cooler

    Science.gov (United States)

    Jacob, S.; Karunanithi, R.; Narsimham, G. S. V. L.; Kranthi, J. Kumar; Damu, C.; Praveen, T.; Samir, M.; Mallappa, A.

    2014-01-01

    Earlier version of an indigenously developed Pressure Wave Generator (PWG) could not develop the necessary pressure ratio to satisfactorily operate a pulse tube cooler, largely due to high blow by losses in the piston cylinder seal gap and due to a few design deficiencies. Effect of different parameters like seal gap, piston diameter, piston stroke, moving mass and the piston back volume on the performance is studied analytically. Modifications were done to the PWG based on analysis and the performance is experimentally measured. A significant improvement in PWG performance is seen as a result of the modifications. The improved PWG is tested with the same pulse tube cooler but with different inertance tube configurations. A no load temperature of 130 K is achieved with an inertance tube configuration designed using Sage software. The delivered PV power is estimated to be 28.4 W which can produce a refrigeration of about 1 W at 80 K.

  18. Quantification of propidium iodide delivery with millisecond electric pulses: A model study

    CERN Document Server

    Yu, Miao

    2014-01-01

    A model study of propidium iodide delivery with millisecond electric pulses is presented; this work is a companion of the experimental efforts by Sadik et al. [1]. Both membrane permeabilization and delivery are examined with respect to six extra-cellular conductivities. The transmembrane potential of the permeabilized regions exhibits a consistent value, which corresponds to a bifurcation point in the pore-radius-potential relation. Both the pore area density and membrane conductance increase with an increasing extra-cellular conductivity. On the other hand, the inverse correlation between propidium iodide delivery and extra-cellular conductivity as observed in the experiments is quantitatively captured by the model. This agreement confirms that this behavior is primarily mediated by electrophoretic transport during the pulse. The results suggest that electrophoresis is important even for the delivery of small molecules such as propidium iodide. The direct comparison between model prediction and experimental...

  19. A study on the pulsed laser printing of liquid-phase exfoliated graphene for organic electronics

    Science.gov (United States)

    Papazoglou, S.; Raptis, Y. S.; Chatzandroulis, S.; Zergioti, I.

    2014-10-01

    The aim of this work is the pulsed laser printing of liquid-phase exfoliated graphene in the nanosecond regime and the optimization of the printing process on Si/SiO2 and flexible polymer substrates (polyethylene naphthalate) via the laser-induced forward transfer technique (LIFT). The laser printing conditions and the optimum energy fluence window for reproducible deposition have been investigated, while the deposited graphene features have been studied morphologically and structurally by means of optical microscopy, micro-Raman spectroscopy and electrical characterization. LIFT experiments were carried out using the fourth harmonic (266 nm) of a pulsed ns Nd:YAG laser combined with a high-power imaging micromachining system to monitor the printing process throughout the experiments. The irradiation of our graphene solution resulted in the deposition of well-resolved patterns on different surfaces, highlighting LIFT as an alternative technique for the printing and patterning of liquid-phase exfoliated graphene for organic electronics applications.

  20. A single-solenoid pulsed-magnet system for single-crystal scattering studies.

    Science.gov (United States)

    Islam, Zahirul; Capatina, Dana; Ruff, Jacob P C; Das, Ritesh K; Trakhtenberg, Emil; Nojiri, Hiroyuki; Narumi, Yasuo; Welp, Ulrich; Canfield, Paul C

    2012-03-01

    We present a pulsed-magnet system that enables x-ray single-crystal diffraction in addition to powder and spectroscopic studies with the magnetic field applied on or close to the scattering plane. The apparatus consists of a single large-bore solenoid, cooled by liquid nitrogen. A second independent closed-cycle cryostat is used for cooling samples near liquid helium temperatures. Pulsed magnetic fields close to ~30 T with a zero-to-peak-field rise time of ~2.9 ms are generated by discharging a 40 kJ capacitor bank into the magnet coil. The unique characteristic of this instrument is the preservation of maximum scattering angle (~23.6°) on the entrance and exit sides of the magnet bore by virtue of a novel double-funnel insert. This instrument will facilitate x-ray diffraction and spectroscopic studies that are impractical, if not impossible, to perform using split-pair and narrow-opening solenoid magnets. Furthermore, it offers a practical solution for preserving optical access in future higher-field pulsed magnets.

  1. A Study on Determination of Strategy for Pulse Industry through SWOT and SOR Analyses in Mersin Province

    Directory of Open Access Journals (Sweden)

    Osman Uysal

    2014-06-01

    Full Text Available Pulse processing industry almost all located in Mersin province in Turkey. Strategic importance considered both national and international trade in terms of capital, domestic and foreign trade connections, knowledge and experience, pulse processing technology Mersin has an important position in the world. However, decline in pulse crops production in recet years, market fluctuations lead companies to import intensively and competitor countries have become major supplier. In the study, these developments in pulse production and trade in recent years, companies and also researchers opinions take into account to determine companies strengths, weaknesses, opportunities, and threats for SWOT analysis with the aim of offer sector-oriented strategies. Results of SWOT analysis were analyzed with SOR analysis. It is tried to develop strategies for development of pulse industry.

  2. STUDY OF THE PROPAGATION OF SHORT PULSE LASER WITH CAVITY USING NUMERICAL SIMULATION SOFTWARE

    Directory of Open Access Journals (Sweden)

    S. Terniche

    2015-07-01

    Full Text Available The purpose of this representation is to show the potentialities (Computational Time, access to the dynamic and feasibility of systematic studies of the numerical study of the nonlinear dynamics in laser cavity, assisted by software. We will give as an example, one type of cavity completely fibered composed of several elements and then studying the physical parameters of a pulse propagating into this cavity, determining its characteristics at the output. The results are interesting but we also projects to verify them experimentally by making assemblies similar to this type of cavities.

  3. Preliminary studies of the quickly pulsed synchrotron involved in the Beta-Beam project; Etudes preliminaires du synchrotron rapidement pulse du projet Beta-Beam

    Energy Technology Data Exchange (ETDEWEB)

    Lachaize, A

    2007-07-01

    This study presents a quickly-pulsed synchrotron able to accelerate He{sup 6} and Ne{sup 18} beams from 100 MeV/u till 3.5 GeV (proton equivalent) The accelerator is made up of 48 bending dipoles and 42 focusing quadrupoles. The design of the HF accelerating system, the bunch injection and the correction of errors in beam dynamics are dealt with.

  4. Controlling micro-sized droplet generation using electrical pulses for studying liquid-liquid systems

    Science.gov (United States)

    Fernandino, M.; La Forgia, N.; Vera, A. J.; Bjerknes, J.; Dorao, C. A.

    2014-04-01

    Water droplets removal from oil is a critical process in several industries, in particular in the oil and gas industry. Water/oil separation is commonly done in large gravitational sedimentation tanks, which are over dimensioned due to the lack of accurate models to allow for optimization. This can become challenging for off-shore and subsea processing installations. One of the bottlenecks to study droplet dynamics in the micron range, is the generation of droplets with less than 100μm in diameter. In this regard, one of the most promising techniques for controlling the generated droplet size is based on the use of a high voltage electrical signal or electro-hydrodynamic technique (EHD). Although much work on EHD and droplet generation can been found in the literature, many challenges still remain. One of this is the generation of droplets smaller than 100μm in diameter in a controllable, on-demand manner. In this work, the effect of the meniscus shape and the electric pulse characteristics on the size of the generated droplet is investigated. Both the meniscus height and width help to determine the droplet size, with the latter having a stronger effect. No significant influence of the pulse amplitude and pulse width was observed for the tested conditions.

  5. Pulsed laser deposition of graphite in air and in vacuum for field emission studies

    Energy Technology Data Exchange (ETDEWEB)

    Jadhav, Harshada; Singh, A.K.; Sinha, Sucharita, E-mail: ssinha@barc.gov.in

    2015-07-15

    A comparative study of pulsed laser deposition (PLD) based carbon films when deposited either, in atmospheric air, or under vacuum, has been performed. Micro-structural characterization of deposited films was carried out employing X-ray diffraction and Raman spectroscopic techniques. While, nanocrystalline graphite phase was observed in carbon films deposited in air, PLD films deposited under vacuum were largely amorphous in nature. Field emission (FE) properties of films deposited in air and under vacuum were investigated. Superior FE behavior characterized by a lower turn-on field (2.72 V/μm) and high field enhancement factor (∼2580) was observed for PLD films deposited in air. This improved field emission demonstrated by carbon films deposited via PLD in air can be attributed to presence of nanocrystalline graphite aggregates in such carbon films and local field enhancement near the sp{sup 2} sites. Our results therefore, establish PLD in air as a simple technique for deposition of carbon films having good field emission capability. - Highlights: • Pulsed laser deposition of graphite films, deposited in air and in vacuum. • Micro-structural, X-ray diffraction and micro-Raman spectroscopic characterization of deposited films. • Field emission properties of deposited films investigated. • Superior field emission behavior observed for films deposited in air than in vacuum. • Pulsed laser deposition in air leads to carbon films with excellent field emission capability.

  6. Design and development of micro pulse lidar for cloud and aerosol studies

    Science.gov (United States)

    Dubey, P. K.; Arya, B. C.; Ahammed, Y. Nazeer; Kumar, Arun; Kulkarni, P. S.; Jain, S. L.

    2008-12-01

    A micro pulse lidar (MPL) has been indigenously designed and developed at the National Physical Laboratory, New Delhi using a 532 nm, 500 pico second pulsed laser having average power of 50mW (at 7.5 KHz PRR). Photon counting technique has been incorporated using the conventional optics, multichannel scaler (Stanford Research Systems SR430) and high sensitive photomultiplier tube. The sensitivity, range and bin etc are computer controlled in the present system. The interfacing between MPL and computer has been achieved by serial (RS232) and parallel printer port. The necessary software and graphical user interface has been developed using visual basic. In addition to this the telescope cover status sensing circuit has been incorporated to avoid conflict between dark count and background acquisition. The micro pulse lidar will be used for the aerosol, boundary layer and the cloud studies at a bin resolution of 6 meters. In the present communication the details of the system and preliminary results will be presented.

  7. A quantum dynamics study of the benzopyran ring opening guided by laser pulses

    Energy Technology Data Exchange (ETDEWEB)

    Saab, Mohamad, E-mail: mohamad.saab@univ-montp2.fr [CTMM, Institut Charles Gerhardt Montpellier (UMR5253), CC 15001, Université Montpellier 2, F-34095 Montpellier (France); Doriol, Loïc Joubert, E-mail: Loic.Joubert-Doriol@univ-montp2.fr [CTMM, Institut Charles Gerhardt Montpellier (UMR5253), CC 15001, Université Montpellier 2, F-34095 Montpellier (France); Lasorne, Benjamin, E-mail: lasorne@univ-montp2.fr [CTMM, Institut Charles Gerhardt Montpellier (UMR5253), CC 15001, Université Montpellier 2, F-34095 Montpellier (France); Guérin, Stéphane, E-mail: sguerin@u-bourgogne.fr [Département Optique, Interaction Matière-Rayonnement (OMR) (UMR 6303), Université de Bourgogne, F-21078 Dijon (France); Gatti, Fabien, E-mail: gatti@univ-montp2.fr [CTMM, Institut Charles Gerhardt Montpellier (UMR5253), CC 15001, Université Montpellier 2, F-34095 Montpellier (France)

    2014-10-17

    Highlights: • We perform quantum mechanical simulations for the ring-opening of benzopyran. • We develop strategies of control with laser pulses. • We focus on the physics involving the conical intersection. - Abstract: The ring-opening photoisomerization of benzopyran, which occurs via a photochemical route involving a conical intersection, has been studied with quantum dynamics calculations using the multi-configuration time-dependent Hartree method (MCTDH). We introduce a mechanistic strategy to control the conversion of benzopyran to merocyanine with laser pulses. We use a six-dimensional model developed in a previous work for the potential energy surfaces (PES) based on an extension of the vibronic-coupling Hamiltonian model (diabatization method by ansatz), which depends on the most active degrees of freedom. The main objective of these quantum dynamics simulations is to provide a set of strategies that could help experimentalists to control the photoreactivity vs. photostability ratio (selectivity). In this work we present: (i) a pump–dump technique used to control the photostability, (ii) a two-step strategy to enhance the reactivity of the system: first, a pure vibrational excitation in the electronic ground state that prepares the system and, second, an ultraviolet excitation that brings the system to the first adiabatic electronic state; (iii) finally the effect of a non-resonant pulse (Stark effect) on the dynamics.

  8. Experimental studies on extremely low frequency pulsed magnetic field inhibiting sarcoma and enhancing cellular immune functions

    Institute of Scientific and Technical Information of China (English)

    张沪生; 叶晖; 张传清; 曾繁清; 黄兴鼎; 张晴川; 李宗山; 杜碧

    1997-01-01

    The previous observation with an electron microscope showed that extremely low frequency (ELF) pulsed magnetic field (PMF) (with the maximum intensity of 0. 6-2. 0 T, gradient of 10-100 T. M-1, pulse width of 20-200 ms and frequency of 0. 16-1. 34 Hz) inhibited the growth of S-180 sarcoma in mice and enhanced the ability of immune cell’s dissolving sarcoma cells. In this study, the DNA contents of nuclei were assayed by using Faulgen Staining method. With an electron microscope and cell stereoscopy technology it was observed that magnetic field affected the sarcoma cell’s metabolism, lowered its malignancy, and restrained its rapid and heteromorphic growth. The magnetic field enhanced the cellular immune ability and the reaction of lymphocytes and plasma. Since ELF pulsed magnetic fields can inhibit the growth of sarcomas and enhance the cellular immune ability, it is possible to use it as a new method to treat cancer.

  9. Comparative study of SVPWM (space vector pulse width modulation) & SPWM (sinusoidal pulse width modulation) based three phase voltage source inverters for variable speed drive

    Science.gov (United States)

    Ahmed, Waheed; Usman Ali, Syed M.

    2013-12-01

    We have performed comparative studies of Space Vector Pulse Width Modulation (SVPWM) and Sinusoidal Pulse Width Modulation (SPWM) techniques utilizing MATLAB tools. During these investigations, we carried out intensive simulations, comprehensively analyzed the obtained results and compared the harmonic density, power factor (PF), & switching losses of SVPWM and SPWM. It has been observed during investigations that if the switching frequency is high then losses due to harmonics are negligible, thus based on obtained results we suggested that the SVPWM technique is a more reliable solution. Because SVPWM utilizes DC bus voltage more efficiently, generates less Total Harmonic Distortion (THD) and has higher output quality it provides flexible control of output voltage and output frequency for Variable Speed Drive (VSD).

  10. The reduction process of phytic acid silver ion system: A pulse radiolysis study

    Science.gov (United States)

    Joshi, Ravi; Mukherjee, Tulsi

    2007-05-01

    Reduction of silver ion in a silver-phytic acid (1:1 ratio) system has been studied using pulse radiolysis technique. Time-resolved transformation of the intermediates, Ag +→Ag 0→Ag 2+→Ag 32+, has been clearly observed in the reduction of silver-phytic acid (1:1) system. The effect of phytic acid on the formation and decay of initial silver clusters has been also studied. The surface plasmon absorption band of stable silver nanoparticle (410 nm) and dynamic light scattering technique has been used to characterize the nanoparticles and measure the average size ( Rav=100 nm).

  11. Development of Nuclear Magnetic Resonance Pulse Sequences and Probes to Study Biomacromolecules

    Energy Technology Data Exchange (ETDEWEB)

    Cosman, M; Krishnan, V V; Maxwell, R

    2001-02-26

    in NMR studies of biomolecules. Our unique combination of expertise at LLNL allowed us to tackle each of the negative features of {sup 31}P-NMR in a three-pronged, concerted effort. The nature of our work necessitated an interdependent, multidisciplinary approach that required knowledge of spin physics (pulse sequences), engineering (probes), and structural biology (sample preparation and structure determination).

  12. Study on the DOP of Output Pulse in Optical Fiber Transmission Systems

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    In this paper the expression of the output pulse Stokes vector is derived based on the Jones matrix model proposed by A.Orlandini et al. The basic properties of degree of polarization (DOP) for output pulse are investigated.

  13. Ablation Study of WC and PCD Composites Using 10 Picosecond and 1 Nanosecond Pulse Durations at Green and Infrared Wavelengths

    Science.gov (United States)

    Eberle, Gregory; Wegener, Konrad

    An ablation study is carried out to compare 10 picosecond and 1 nanosecond pulse durations as well as 532 nanometre and 1064 nanometre wavelengths at each corresponding pulse duration. All laser parameters are kept constant in order to understand the influence of pulse duration and wavelength independently. The materials processed according to the electronic band structure are a metal and an insulator/metal composite, i.e. tungsten carbide and polycrystalline diamond composite respectively. After laser processing said materials, the ablation rate and surface roughness are determined. Analysis into the ablation behaviour between the various laser parameters and the materials processed is given, with a particular emphasis on the graphitisation of diamond.

  14. Design and Study of Data Acquisition System for Pulsed γ Dose Measurement Device

    Institute of Scientific and Technical Information of China (English)

    DOU; Yu-ling; YANG; Shao-hua; ZHANG; Guo-guang

    2012-01-01

    <正>A data acquisition system for online pulsed gamma dose measurement device was designed and developed (Fig. 1), and its performance was tested. The results show that the data acquisition system in both the continued and pulsed input, output electric charges and input energy have a good linear relationship. Experiments were done respectively on the XRS-3 pulsed source and re-frequency

  15. Use of pulse radiolysis for the study of the chemistry of aqueous ozone and ozonide solutions

    DEFF Research Database (Denmark)

    Sehested, Knud; Holcman, Jerzy; Bjergbakke, Erling

    1986-01-01

    The chemistry of aqeous ozone, O3, and ozonide, O3−, is of great interest from a technological, environmental and scientific point of view. The literature about their aqueous chemistry is extensive, the reaction mechanisms are still not well understood. The ozonide anion is a free radical...... of a detailed mechanism. We have investigated the reaction mechanisms using pulse radiolysis in combination with a high pressure cell, rapid mixing and numerical simulation of the experiments. This study makes it possible to give a detailed description of the reaction mechanisms in terms of uni- and bimolecular...... reactions and provides kinetic data sufficient for computer simulations of aqueous O3/O3− chemistry....

  16. Study of transient wave propagation in plates using double pulse TV holography

    OpenAIRE

    Lopes, H.; Guedes, R. M.; M. A. P. Vaz; Rodrigues, J.D.

    2004-01-01

    This work presents a numerical and experimental study of the transient response of an isotropic plate. A low mass impact is used to generate the bending wave propagation. Displacements due to the bending wave propagation were assessed using an out-of-plane double pulse TV holography set-up. A PZT transducer is used to record the impact force and its temporal evolution. A novel experimental technique is presented for determination of the stress field in the plate using the out-of-plane ...

  17. Studies of nanosecond pulsed power for modifications of biomaterials and nanomaterials (SWCNT)

    Science.gov (United States)

    Chen, Meng-Tse

    This work investigates the modification of biological materials through the applications of modern nanosecond pulsed power, along with other forms of nanotechnologies. The work was initially envisaged as a study of the effect of intense nanosecond pulsed electric fields on cancer cells. As the work progressed, the studies suggested incorporation of additional technologies, in particular, cold plasmas, and carbon nanotubes. The reasons for these are discussed below, however, they were largely suggested by the systems that we were studying, and resulted in new and potentially important medical therapies. Using nanosecond cold plasmas powered with nanosecond pulses, collaboration with endodontists and biofilm experts demonstrated a killing effect on biofilms deep within root canals, suggesting a fundamentally new approach to an ongoing problem of root canal sterilization. This work derived from the application of nanosecond pulsed power, resulting in effective biofilm disinfection, without excessive heating, and is being investigated for additional dental and other medical applications. In the second area, collaboration with medical and nanotube experts, studies of gliomamultiforme (GBM) led to the incorporation of functionalized carbon nanotubes. Single-walled carbon nanotube-fluorescein carbazide (SWCNT-FC) conjugates demonstrated that the entry mechanism of the single-walled carbon nanotubes (SWCNTs) was through an energy-dependent endocytotic pathway. Finally, a monotonic pH sensitivity of the intracellular fluorescence emission of SWCNT-FC conjugates in human ovarian cancer cells suggests these conjugates may serve as intracellular pH sensors. Light-stimulated intracellular hydrolysis of the amide linkage and localized intracellular pH changes are proposed as mechanisms. The use of SWCNTs for cancer therapy of gliomas, resulting in hyperthermia effect after 808 nm infrared radiations, absorbed specifically by SWCNTs but not by biological tissue. Heat was only

  18. Optimum Pulse Duration and Radiant Exposure for Vascular Laser Therapy of Dark port-wine Skin: A Theoretical Study

    Science.gov (United States)

    Tunnell, James W.; Wang, Lihong V.; Anvari, Bahman

    2003-03-01

    Laser therapy for cutaneous hypervascular malformations such as port-wine stain birthmarks is currently not feasible for dark-skinned individuals. We study the effects of pulse duration, radiant exposure, and cryogen spray cooling (CSC) on the thermal response of skin, using a Monte Carlo based optical-thermal model. Thermal injury to the epidermis decreases with increasing pulse duration during irradiation at a constant radiant exposure; however, maintaining vascular injury requires that the radiant exposure also increase. At short pulse durations, only a minimal increase in radiant exposure is necessary for a therapeutic effect to be achieved because thermal diffusion from the vessels is minimal. However, at longer pulse durations the radiant exposure must be greatly increased. There exists an optimum pulse duration at which minimal damage to the epidermis and significant injury within the targeted vasculature occur. For example, the model predicts optimum pulse durations of approximately 1.5, 6, and 20 ms for vessel diameters of 40, 80, and 120 μm, respectively. Optimization of laser pulse duration and radiant exposure in combination with CSC may offer a means to treat cutaneous lesions in dark-skinned individuals.

  19. Comparative study of electrical breakdown properties of deionized water and heavy water under pulsed power conditions

    Energy Technology Data Exchange (ETDEWEB)

    Veda Prakash, G.; Kumar, R.; Saurabh, K.; Nasir,; Anitha, V. P.; Chowdhuri, M. B.; Shyam, A. [Institute for Plasma Research, Bhat, Gandhinagar 382428 (India)

    2016-01-15

    A comparative study of electrical breakdown properties of deionized water (H{sub 2}O) and heavy water (D{sub 2}O) is presented with two different electrode materials (stainless steel (SS) and brass) and polarity (positive and negative) combinations. The pulsed (∼a few tens of nanoseconds) discharges are conducted by applying high voltage (∼a few hundred kV) pulse between two hemisphere electrodes of the same material, spaced 3 mm apart, at room temperature (∼26-28 °C) with the help of Tesla based pulse generator. It is observed that breakdown occurred in heavy water at lesser voltage and in short duration compared to deionized water irrespective of the electrode material and applied voltage polarity chosen. SS electrodes are seen to perform better in terms of the voltage withstanding capacity of the liquid dielectric as compared to brass electrodes. Further, discharges with negative polarity are found to give slightly enhanced discharge breakdown voltage when compared with those with positive polarity. The observations corroborate well with conductivity measurements carried out on original and post-treated liquid samples. An interpretation of the observations is attempted using Fourier transform infrared measurements on original and post-treated liquids as well as in situ emission spectra studies. A yet another important observation from the emission spectra has been that even short (nanosecond) duration discharges result in the formation of a considerable amount of ions injected into the liquid from the electrodes in a similar manner as reported for long (microseconds) discharges. The experimental observations show that deionised water is better suited for high voltage applications and also offer a comparison of the discharge behaviour with different electrodes and polarities.

  20. Pulsed application of focused ultrasound to the LI4 elicits deqi sensations: pilot study.

    Science.gov (United States)

    Yoo, Seung-Schik; Lee, Wonhye; Kim, Hyungmin

    2014-08-01

    Focused ultrasound (FUS) techniques enable the delivery of acoustic pressure waves to a localized, specific region of anatomy, and mechanically stimulate the sonicated region when given in a train of pulses. The present pilot study examines if the pulsed application of acoustic waves focused to an acupuncture point (LI4, Hegu), i.e. FUS acupuncture, can elicit deqi sensations. The FUS was generated by a single-element ultrasound transducer, and delivered to the LI4 of acupuncture-naïve participants (n=10) for a duration of 1s using 2 ms tone-burst-duration and 50 Hz pulse repetition frequency. The subjective ratings of deqi descriptors were obtained across different conditions, i.e. FUS acupuncture using acoustic intensities of 1 and 3 W/cm(2) (spatial-peak temporal-averaged intensity, Ispta), sham sonication condition, tactile stimulation using a von Frey monofilament, and needle-based real and sham acupuncture. We also measured the presence of sharp pain, unpleasantness, and anxiety level during each condition. The FUS acupuncture given at 3 W/cm(2) elicited deqi sensation ratings similar to those acquired during the needle-based acupuncture condition across the subjects, with significantly reduced levels of non-deqi related sensations, such as sharp pain, anxiety and unpleasantness. The lower acoustic intensity also generated deqi sensations, but at a lesser degree than the ones acquired using the higher acoustic intensity. Neither the sham conditions nor the tactile stimulation elicited deqi sensations. The present data on acoustic acupuncture, with its exquisite spatial and depth control, along with the ability to electronically adjust its intensity, may suggest its potential utilization as an alternative mode of acupuncture, although further study is needed to probe its clinical efficacy. Copyright © 2014 Elsevier Ltd. All rights reserved.

  1. Study of plasma produced from deuterized-titanium irradiated by intense laser pulses

    Science.gov (United States)

    Skladnik-Sadowska, E.; Malinowski, K.; Sadowski, M. J.; Wolowski, J.; Kubkowska, M.; Gasior, P.; Rosinski, M.; Ladygina, M.

    2010-10-01

    The paper reports on experimental studies of plasma generated by the irradiation of pure titanium (Ti) and deuterium-saturated (Ti+D 2) targets with intense laser beams from a Nd:YAG system operated at 1063 nm (0.5 J) or at 355 nm (0.1 J). The FWHM of laser pulses was 3 ns and the laser power density on the target surface amounted to (0.7- 3)×1010 W/cm2. Spectroscopic studies of plasma plumes were performed with a Mechelle®900 spectrometer in the wavelength range of 300-1100 nm, at a variable exposition time. The recorded spectra showed numerous lines originating from different Ti-ions and D+ desorbed from the (Ti+D 2) target. Estimates of electron temperatures during the plasma expansion gave T e=1.4-2 eV for 0.1 J pulses and 2.3-3 eV for 0.5 J ones. In the Ti+D 2 experiment, the electron density, as estimated from the Dα line, was N e=(1.8- 4.6)×1016 cm-3 and (1.9- 2.1)×1017 cm-3 for 0.1 and 0.5 J pulses, respectively. For the given T e, it was estimated that the Ti-I component density was about one order lower. The emission of D+ and various Ti-ions (ranging from Ti+ to Ti+14) was confirmed by corpuscular measurements, which gave higher values of energy ⟨ E Ti⟩=420-1200 eV and electron temperature T e=12-34 eV for the initial hot-plasma phase.

  2. Circadian response reduction in light and response restoration in darkness: a "skeleton" light pulse PRC study in mice (Mus musculus).

    Science.gov (United States)

    Comas, M; Beersma, D G M; Spoelstra, K; Daan, S

    2007-10-01

    Entrainment may involve responses to dawn, to dusk, and to the light in between these transitions. Previous studies showed that the circadian system responds to only 2 light pulses, one at the beginning and one at the end of the day, in a similar way as to a full photoperiod, as long as the photoperiod is less than approximately 1/2 tau. The authors used a double 1-h light pulse protocol with different intervals of darkness in between (1, 2, 4, 7, 10, and 16 h) to study the phase responses of mice. The phase response curves obtained were compared to full light pulse PRCs of corresponding durations. Up to 6 hours, phase responses induced by double light pulses are virtually the same as by a corresponding full light pulse. The authors made a simple phase-only model to estimate the response reduction due to light exposure and response restoration due to dark exposure of the system. In this model, they assumed a 100% contribution of the first 1-h light pulse and fitted the reduction factor for the second light pulse to yield the best fit to the observations. The results suggest that after 1 h of light followed by less than 4 h of darkness, there is a considerable reduction in response to the second light pulse. Full response restoration requires more than 10 h of darkness. To investigate the influence of the duration of light on the response saturation, the authors performed a second series of experiments where the duration of the 2 light pulses was varied from 4 to 60 min each with a fixed duration of the stimulus (4 h). The response to 2 light pulses saturates when they are between 30 and 60 min long. In conclusion, double pulses replace single full light pulses of a corresponding duration of up to 6 h due to a response reduction during light, combined with response restoration during darkness. By the combined response reduction and response restoration, mice can maintain stable entrainment to the external LD cycle without being continuously exposed to it.

  3. A comparative study on continuous and pulsed RF argon capacitive glow discharges at low pressure by fluid modeling

    Science.gov (United States)

    Liu, Ruiqiang; Liu, Yue; Jia, Wenzhu; Zhou, Yanwen

    2017-01-01

    Based on the plasma fluid theory and using the drift-diffusion approximation, a mathematical model for continuous and pulsed radial frequency (RF) argon capacitive glow discharges at low pressure is established. The model is solved by a finite difference method and the numerical results are reported. Based on the systematic analysis of the results, plasma characteristics of the continuous and pulsed RF discharges are comparatively investigated. It is shown that, under the same condition for the peak value of the driving potential, the cycle-averaged electron density, the current density, and other essential physical quantities in the continuous RF discharge are higher than those from the pulsed RF discharge. On the other hand, similar plasma characteristics are obtained with two types of discharges, by assuming the same deposited power. Consequently, higher driving potential is needed in pulsed discharges in order to maintain the same effective plasma current. Furthermore, it is shown that, in the bulk plasma region, the peak value of the bipolar electric field from the continuous RF discharge is greater than that from the pulsed RF discharge. In the sheath region, the ionization rate has the shape of double-peaking and the explanation is given. Because the plasma input power depends on the driving potential and the plasma current phase, the phase differences between the driving potential and the plasma current are compared between the continuous and the pulsed RF discharges. It is found that this phase difference is smaller in the pulsed RF discharge compared to that of the continuous RF discharge. This means that the input energy coupling in the pulsed RF discharge is less efficient than the continuous counterpart. This comparative study, carried out also under other conditions, thus can provide instructive ideas in applications using the continuous and pulsed RF capacitive glow discharges.

  4. Analytical study of pulsed laser irradiation on some materials used for photovoltaic cells on satellites

    Directory of Open Access Journals (Sweden)

    Afaf M. Abd El-Hameed

    2015-12-01

    Full Text Available The present research concerns on the study of laser-powered solar panels used for space applications. A mathematical model representing the laser effects on semiconductors has been developed. The temperature behavior and heat flow on the surface and through a slab has been studied after exposed to nano-second pulsed laser. The model is applied on two different types of common active semiconductor materials that used for photovoltaic cells fabrication as silicon (Si, and gallium arsenide (GaAs. These materials are used for receivers’ manufacture for laser beamed power in space. Various values of time are estimated to clarify the heat flow through the material sample and generated under the effects of pulsed laser irradiation. These effects are theoretically studied in order to determine the performance limits of the solar cells when they are powered by laser radiation during the satellite eclipse. Moreover, the obtained results are carried out to optimize conversion efficiency of photovoltaic cells and may be helpful to give more explanation for layout of the light-electricity space systems.

  5. Analytical study of pulsed laser irradiation on some materials used for photovoltaic cells on satellites

    Science.gov (United States)

    Abd El-Hameed, Afaf M.

    2015-12-01

    The present research concerns on the study of laser-powered solar panels used for space applications. A mathematical model representing the laser effects on semiconductors has been developed. The temperature behavior and heat flow on the surface and through a slab has been studied after exposed to nano-second pulsed laser. The model is applied on two different types of common active semiconductor materials that used for photovoltaic cells fabrication as silicon (Si), and gallium arsenide (GaAs). These materials are used for receivers' manufacture for laser beamed power in space. Various values of time are estimated to clarify the heat flow through the material sample and generated under the effects of pulsed laser irradiation. These effects are theoretically studied in order to determine the performance limits of the solar cells when they are powered by laser radiation during the satellite eclipse. Moreover, the obtained results are carried out to optimize conversion efficiency of photovoltaic cells and may be helpful to give more explanation for layout of the light-electricity space systems.

  6. Scoping Study of Airlift Circulation Technologies for Supplemental Mixing in Pulse Jet Mixed Vessels

    Energy Technology Data Exchange (ETDEWEB)

    Schonewill, Philip P. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Berglin, Eric J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Boeringa, Gregory K. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Buchmiller, William C. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Burns, Carolyn A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Minette, Michael J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2015-04-07

    At the request of the U.S. Department of Energy Office of River Protection, Pacific Northwest National Laboratory (PNNL) conducted a scoping study to investigate supplemental technologies for supplying vertical fluid motion and enhanced mixing in Waste Treatment and Immobilization Plant (WTP) vessels designed for high solids processing. The study assumed that the pulse jet mixers adequately mix and shear the bottom portion of a vessel. Given that, the primary function of a supplemental technology should be to provide mixing and shearing in the upper region of a vessel. The objective of the study was to recommend a mixing technology and configuration that could be implemented in the 8-ft test vessel located at Mid-Columbia Engineering (MCE). Several mixing technologies, primarily airlift circulator (ALC) systems, were evaluated in the study. This technical report contains a review of ALC technologies, a description of the PNNL testing and accompanying results, and recommended features of an ALC system for further study.

  7. Ultra-short laser pulse ablation using shear-force feedback: Femtosecond laser induced breakdown spectroscopy feasibility study

    Energy Technology Data Exchange (ETDEWEB)

    Samek, Ota [ISAS-Institute for Analytical Sciences, Bunsen-Kirchhoff Str.11, 44139 Dortmund (Germany)]. E-mail: samek@ansci.de; Kurowski, Andre [ISAS-Institute for Analytical Sciences, Bunsen-Kirchhoff Str.11, 44139 Dortmund (Germany); Kittel, Silke [ISAS-Institute for Analytical Sciences, Bunsen-Kirchhoff Str.11, 44139 Dortmund (Germany); Kukhlevsky, Sergei [Institute of Physics, University of Pecs, Ifjusag u. 6, Pecs 7624 (Hungary); Hergenroeder, Roland [ISAS-Institute for Analytical Sciences, Bunsen-Kirchhoff Str.11, 44139 Dortmund (Germany)

    2005-08-31

    This work reports on a feasibility study of proximity ablation using femtosecond pulses. Ultra-short pulses were launched to a bare tapered optical fiber and delivered to the sample. The tip-sample distance was controlled by means of shear-force feedback. Consequently, ablation craters with submicrometer dimensions were obtained. Potential analytical applications for Laser Induced Breakdown Spectroscopy (LIBS) technique, such as e.g. inclusions in steel or bio cells, are suggested.

  8. Validity and reproducibility of arterial pulse wave velocity measurement using new device with oscillometric technique: A pilot study

    Directory of Open Access Journals (Sweden)

    Patnaik Amar

    2005-08-01

    Full Text Available Abstract Background Availability of a range of techniques and devices allow measurement of many variables related to the stiffness of large or medium sized arteries. There is good evidence that, pulse wave velocity is a relatively simple measurement and is a good indicator of changes in arterial properties. The pulse wave velocity calculated from pulse wave recording by other methods like doppler or tonometry is tedious, time-consuming and above all their reproducibility depends on the operator skills. It requires intensive resource involvement. For epidemiological studies these methods are not suitable. The aim of our study was to clinically evaluate the validity and reproducibility of a new automatic device for measurement of pulse wave velocity that can be used in such studies. Methods In 44 subjects including normal healthy control and patients with coronary artery disease, heart brachial, heart ankle, brachial ankle and carotid femoral pulse wave velocities were recorded by using a new oscillometric device. Lead I and II electrocardiogram and pressure curves were simultaneously recorded. Two observers recorded the pulse wave velocity for validation and one observer recorded the velocity on two occasions for reproducibility. Results and Discussion Pulse wave velocity and arterial stiffness index were recorded in 24 control and 20 coronary artery disease patients. All the velocities were significantly high in coronary artery disease patients. There was highly significant correlation between the values noted by the two observers with low standard deviation. The Pearson's correlation coefficient for various velocities ranged from (r = 0.88–0.90 with (p Conclusion The new device "PeriScope" based on oscillometric technique has been found to be a simple, non-invasive and reproducible device for the assessment of pulse wave velocity and can be used to determine arterial stiffness in large population based studies.

  9. Improved digestibility of β-lactoglobulin by pulsed light processing: a dilatational and shear study.

    Science.gov (United States)

    del Castillo-Santaella, Teresa; Sanmartín, Esther; Cabrerizo-Vílchez, Miguel Angel; Arboleya, Juan Carlos; Maldonado-Valderrama, Julia

    2014-12-28

    Modifying the protein conformation appears to improve the digestibility of proteins in the battle against allergies. However, it is important not to lose the protein functionality in the process. Light pulse technology has been recently tested as an efficient non-thermal process which alters the conformation of proteins while improving their functionality as stabilizers. Also, in order to rationally design emulsion based food products with specific digestion profiles, we need to understand how interfacial composition influences the digestion of coated interfaces. This study has been designed to investigate the effects of pulsed light (PL) treatment on the gastrointestinal digestion of protein covered interfaces. We have used a combination of dilatational and shear rheology which highlights inter and intra-molecular interactions providing new molecular details on protein digestibility. The in vitro digestion model analyses sequentially pepsinolysis, trypsinolysis and lipolysis of β-lactoglobulin (BLG) and pulsed light treated β-lactoglobulin (PL-BLG). The results show that the PL-treatment seems to facilitate digestibility of the protein network, especially regarding trypsinolysis. Firstly, PL treatment just barely enhances the enzymatic degradation of BLG by pepsin, which dilutes and weakens the interfacial layer, due to increased hydrophobicity of the protein owing to PL-treatment. Secondly, PL treatment importantly modifies the susceptibility of BLG to trypsin hydrolysis. While it dilutes the interfacial layer in all cases, it strengthens the BLG and weakens the PL-BLG interfacial layer. Finally, this weakening appears to slightly facilitate lipolysis as evidenced by the results obtained upon addition of lipase and bile salts (BS). This research allows identification of the interfacial mechanisms affecting enzymatic hydrolysis of proteins and lipolysis, which demonstrates an improved digestibility of PL-BLG. The fact that PL treatment did not affect the

  10. Simultaneous acquisition of pulse EPR orientation selective spectra

    Science.gov (United States)

    Kaminker, Ilia; Florent, Marc; Epel, Boris; Goldfarb, Daniella

    2011-01-01

    High resolution pulse EPR methods are usually applied to resolve weak magnetic electron-nuclear or electron-electron interactions that are otherwise unresolved in the EPR spectrum. Complete information regarding different magnetic interactions, namely, principal components and orientation of principal axis system with respect to the molecular frame, can be derived from orientation selective pulsed EPR measurements that are performed at different magnetic field positions within the inhomogeneously broadened EPR spectrum. These experiments are usually carried out consecutively, namely a particular field position is chosen, data are accumulated until the signal to noise ratio is satisfactory, and then the next field position is chosen and data are accumulated. Here we present a new approach for data acquisition of pulsed EPR experiments referred to as parallel acquisition. It is applicable when the spectral width is much broader than the excitation bandwidth of the applied pulse sequence and it is particularly useful for orientation selective pulse EPR experiments. In this approach several pulse EPR measurements are performed within the waiting (repetition) time between consecutive pulse sequences during which spin lattice relaxation takes place. This is achieved by rapidly changing the main magnetic field, B0, to different values within the EPR spectrum, performing the same experiment on the otherwise idle spins. This scheme represents an efficient utilization of the spectrometer and provides the same spectral information in a shorter time. This approach is demonstrated on W-band orientation selective electron-nuclear double resonance (ENDOR), electron spin echo envelope modulation (ESEEM), electron-electron double resonance (ELDOR) - detected NMR and double electron-electron resonance (DEER) measurements on frozen solutions of nitroxides. We show that a factors of 3-6 reduction in total acquisition time can be obtained, depending on the experiment applied.

  11. Semianalytical study of the propagation of an ultrastrong femtosecond laser pulse in a plasma with ultrarelativistic electron jitter

    Energy Technology Data Exchange (ETDEWEB)

    Jovanović, Dušan, E-mail: dusan.jovanovic@ipb.ac.rs [Institute of Physics, University of Belgrade, Pregrevica 118, 11080 Belgrade, Zemun (Serbia); Fedele, Renato, E-mail: renato.fedele@na.infn.it [Dipartimento di Fisica, Università di Napoli “Federico II,” M.S. Angelo, Napoli (Italy); INFN Sezione di Napoli, Complesso Universitario di M.S. Angelo, Napoli (Italy); Belić, Milivoj, E-mail: milivoj.belic@qatar.tamu.edu [Texas A and M University at Qatar, P.O. Box 23874, Doha (Qatar); De Nicola, Sergio, E-mail: sergio.denicola@spin.cnr.it [SPIN-CNR, Complesso Universitario di M.S. Angelo, Napoli (Italy)

    2015-04-15

    The interaction of a multi-petawatt, pancake-shaped laser pulse with an unmagnetized plasma is studied analytically and numerically in a regime with ultrarelativistic electron jitter velocities, in which the plasma electrons are almost completely expelled from the pulse region. The study is applied to a laser wakefield acceleration scheme with specifications that may be available in the next generation of Ti:Sa lasers and with the use of recently developed pulse compression techniques. A set of novel nonlinear equations is derived using a three-timescale description, with an intermediate timescale associated with the nonlinear phase of the electromagnetic wave and with the spatial bending of its wave front. They describe, on an equal footing, both the strong and the moderate laser intensity regimes, pertinent to the core and to the edges of the pulse. These have fundamentally different dispersive properties since in the core the electrons are almost completely expelled by a very strong ponderomotive force, and the electromagnetic wave packet is imbedded in a vacuum channel, thus having (almost) linear properties. Conversely, at the pulse edges, the laser amplitude is smaller, and the wave is weakly nonlinear and dispersive. New nonlinear terms in the wave equation, introduced by the nonlinear phase, describe without the violation of imposed scaling laws a smooth transition to a nondispersive electromagnetic wave at very large intensities and a simultaneous saturation of the (initially cubic) nonlocal nonlinearity. The temporal evolution of the laser pulse is studied both analytically and by numerically solving the model equations in a two-dimensional geometry, with the spot diameter presently used in some laser acceleration experiments. The most stable initial pulse length is estimated to exceed ≳1.5–2 μm. Moderate stretching of the pulse in the direction of propagation is observed, followed by the development of a vacuum channel and of a very large

  12. Effect of intense pulsed light on immature burn scars: A clinical study

    Directory of Open Access Journals (Sweden)

    Arindam Sarkar

    2014-01-01

    Full Text Available Introduction: As intense pulsed light (IPL is widely used to treat cutaneous vascular malformations and also used as non-ablative skin rejunuvation to remodel the skin collagen. A study has been undertaken to gauze the effect of IPL on immature burn scars with regard to vascularity, pliability and height. Materials and Methods: This study was conducted between June 2013 and May 2014, among patients with immature burn scars that healed conservatively within 2 months. Photographic evidence of appearance of scars and grading and rating was done with Vancouver Scar Scale parameters. Ratings were done for both case and control scar after the completion of four IPL treatment sessions and were compared. Results: Out of the 19 cases, vascularity, pliability and height improved significantly (P < 0.05 in 13, 14 and 11 scars respectively following IPL treatment. Conclusions: Intense pulsed light was well-tolerated by patients, caused good improvement in terms of vascularity, pliability, and height of immature burn scar.

  13. a Study of a High Frequency Miniature Reservoir-Less Pulse Tube

    Science.gov (United States)

    Garaway, I.; Grossman, G.

    2008-03-01

    A miniature high frequency reservoir-less pulse tube cryocooler has been designed and tested in our laboratory. The cryocooler having a regenerator length of 12.0 mm and an overall volume of 2.3cc (excluding the compressor) reached a low temperature of 146K and provided 100mW of cooling at 160K. This experimental study shows that it is possible to miniaturize a pulse tube cryocooler to very short regenerator lengths by implementing a few basic principles: Most importantly, high operating frequencies at small tidal displacements, a regenerator matrix with small hydraulic diameters, and increased helium fill pressures. This study also shows that as the operating frequency of a miniature cryocooler increases, the reservoir becomes less necessary as a phase shifting device. At higher frequencies and appropriate inertance tube geometries, the impedance and capacitance of the inertance tube itself takes over the phase shifting task. An outline of the design and modeling principles is presented along with some details of the experimental apparatus and testing procedures.

  14. Comparative Study of Cu Films Prepared by DC, High-Power Pulsed and Burst Magnetron Sputtering

    Science.gov (United States)

    Solovyev, A. A.; Oskirko, V. O.; Semenov, V. A.; Oskomov, K. V.; Rabotkin, S. V.

    2016-08-01

    A comparative study of deposition rate, adhesion, structural and electrical properties of nanocrystalline copper thin films deposited using direct current magnetron sputtering (DCMS) and different regimes of high power pulsed magnetron sputtering is presented. High-power impulse magnetron sputtering (HIPIMS) and burst regime (pulse packages) of magnetron sputtering are investigated. The ion and atomic flows toward the growing film during magnetron sputtering of a Cu target are determined. X-ray diffraction, scanning electron microscopy and atomic force microscopy were used to observe the structural characterization of the films. The resistivity of the films was measured using four-point probe technique. In all sputtering regimes, Cu films have mixture crystalline orientations of [111], [200], [311] and [220] in the direction of the film growth. As peak power density in studied deposition regimes was different in order of magnitude (from 15 W/cm2 in DC regime to 3700 W/cm2 in HIPIMS), film properties were also greatly different. DCMS Cu films exhibit a porous columnar grain structure. In contrast, HIPIMS Cu films have a slightly columnar and denser composition. Cu films deposited using burst regimes at peak power density of 415 W cm-2 and ion-to-atom ratio of about 5 have the densest composition and smallest electrical resistance.

  15. A Micro-PIV Study of the Pulsed Micro-Flows Driven by an Insulin Pump

    Science.gov (United States)

    Wang, Bing; Demuren, Ayodeji; Gyuricsko, Eric; Hu, Hui

    2009-11-01

    In recent years, there is a surge in the popularity of using insulin pump or continuous subcutaneous insulin infusion therapy, as opposed to multiple daily injections by insulin syringe or an insulin pen. Some case studies have suggested that insulin delivery failure may be caused by precipitation of insulin within the infusion set. Speculation also exists that the flow of insulin through an insulin infusion set may be reduced or inhibited by air bubbles entrained into the micro-sized tubing system since there are chances that air be introduced into the insulin reservoir during the filling process. In the present study, a microscopic Particle Image Velocimtry (micro-PIV) system was used to characterize the transient behavior of the pulsed micro-flows inside the micro-sized tubing system of an insulin infusion set with insulin pump operating in basal mode (i.e., pulsed insulin pumping). The effects of the air bubbles entrained into the micro-sized tubing system on the insulin delivery process were assessed based on the micro-PIV measurements.

  16. Study on the Disinfection Technology of Electromagnetic Pulse%电磁脉冲灭菌研究

    Institute of Scientific and Technical Information of China (English)

    周蔚红; 张钧

    2000-01-01

    The effects of disinfection technology between transient electromagnetic pulse and continuous microwave were compared. The mechanism of the disinfection was analysed through electronic pulse and magnetic pulse. Based on this study,a new method of disinfection using electromagnetic pulse for keeping food fresh is brought forward.%本文对比了瞬态电磁脉冲与连续波电磁场的消毒灭菌作用,从脉冲电场、脉冲磁场两方面分析了瞬态电磁脉冲的灭菌机理,提出将电磁脉冲的非热生物效应应用于食品的消毒杀菌,为食品保鲜业的发展开拓一种新方法。

  17. Study of the mechanisms of flux enhancement through hairless mouse skin by pulsed DC iontophoresis

    Energy Technology Data Exchange (ETDEWEB)

    Pikal, M.J.; Shah, S. (Lilly Research Laboratories, Eli Lilly Co., Indianapolis, IN (USA))

    1991-03-01

    Enhanced iontophoretic transport using pulsed DC is usually explained by citing the observed decrease in skin resistance caused by an increase in AC pulse frequency at very small currents. Alternately, it has been suggested that the on-to-off nature of pulsed DC imparts an impact energy to the fluid, thereby increasing transport. This report provides a test of these mechanisms for enhanced delivery via pulsed iontophoresis. The DC resistance of hairless mouse skin during continuous and pulsed DC iontophoresis is measured as a function of time for selected pulse frequencies and duty cycles using current densities ranging from 0.1 to 1.0 mA/cm2. As a test of the impact energy mechanism, the iontophoretic transport of 14C-glucose measured with pulsed DC is compared with similar data obtained previously using continuous DC. It is suggested that pulsed current can yield lower resistance and enhanced drug delivery provided that (a) the steady-state current during the on phase of the pulse is very small and (b) the frequency is low enough to allow depolarization of the skin during the off phase of the pulse. The glucose transport results suggest that the impact energy concept does not apply to iontophoresis.

  18. Electron thermalization and attachment in pulse-irradiated oxygen studied by time-resolved microwave conductivity

    Energy Technology Data Exchange (ETDEWEB)

    Warman, J.M. (Technische Univ., Delft (Netherlands). Dept. of Radiation Chemistry); Cooper, Ronald (Melbourne Univ., Parkville (Australia). Dept. of Physical Chemistry)

    1990-01-01

    The microwave conductivity of oxygen gas following nanosecond pulsed irradiation has been studied for pressures from 5 to 50 torr. The conductivity is found to decrease by a factor of approx. 20 in the early stages (tN < 2 x 10{sup 11} s cm{sup -3}) following the pulse. This is attributed to a decrease in the electron collision frequency as the initial excess energy of the electrons becomes degraded. A further decrease found at longer times is due to the three-body attachment of electrons to O{sub 2} with a rate constant of 2.4 x 10{sup -30} cm{sup 6}s{sup -1}. Above a pressure of approx. 30 torr significant attachment begins to occur while electrons are still superthermal. The time at which the microwave signal is within 10% of the value corresponding to thermal energies is given by {tau}{sub th}P approx = 15 {mu}s.torr. (author).

  19. The Feasibility and Validity of a Remote Pulse Oximetry System for Pulmonary Rehabilitation: A Pilot Study

    Directory of Open Access Journals (Sweden)

    Jonathan Tang

    2012-01-01

    Full Text Available Pulmonary rehabilitation is an effective treatment for people with chronic obstructive pulmonary disease. However, access to these services is limited especially in rural and remote areas. Telerehabilitation has the potential to deliver pulmonary rehabilitation programs to these communities. The aim of this study was threefold: to establish the technical feasibility of transmitting real-time pulse oximetry data, determine the validity of remote measurements compared to conventional face-to-face measures, and evaluate the participants’ perception of the usability of the technology. Thirty-seven healthy individuals participated in a single remote pulmonary rehabilitation exercise session, conducted using the eHAB telerehabilitation system. Validity was assessed by comparing the participant's oxygen saturation and heart rate with the data set received at the therapist’s remote location. There was an 80% exact agreement between participant and therapist data sets. The mean absolute difference and Bland and Altman’s limits of agreement fell within the minimum clinically important difference for both oxygen saturation and heart rate values. Participants found the system easy to use and felt confident that they would be able to use it at home. Remote measurement of pulse oximetry data for a pulmonary rehabilitation exercise session was feasible and valid when compared to conventional face-to-face methods.

  20. Magnetic anisotropy studies on pulsed electrodeposited Ni/Ag/Ni trilayer

    Energy Technology Data Exchange (ETDEWEB)

    Dhanapal, K.; Revathy, T.A.; Raj, M. Anand [Materials Science Centre, Department of Nuclear Physics, University of Madras, Guindy Campus, Chennai 600 025 (India); Narayanan, V. [Department of Inorganic Chemistry, University of Madras, Guindy Campus, Chennai 600 025 (India); Stephen, A., E-mail: stephen_arum@hotmail.com [Materials Science Centre, Department of Nuclear Physics, University of Madras, Guindy Campus, Chennai 600 025 (India)

    2014-09-15

    Highlights: • Ni/Ag/Ni layered film has been prepared using pulsed electrodeposition method. • Crystalline nature of layered films is confirmed using XRD. • Magnetic easy axis is observed to be parallel to the plane of the film. • Magnetic anisotropy change is dependent on number of layers. • Ni/Ag/Ni layered film shows higher anisotropy energy than pure Ni film. - Abstract: The pulsed electrodeposition method was employed for the deposition of pure Ni, Ni/Ag and Ni/Ag/Ni films due to its greater advantages while comparing with other methods. The X-ray diffraction pattern confirms the formation of fcc structure for both nickel and silver. The cross sectional scanning electron microscopy shows the layer formation in Ni/Ag and Ni/Ag/Ni films. The metallic nature of the nickel and silver were also confirmed using X-ray photoelectron spectroscopy. The magnetic anisotropy behaviour was studied using vibrating sample magnetometer which gives that the easy axis is in plan of the film for all the film.

  1. Fenestration operation in middle ear bone with pulsed infrared lasers:an in-vivo study

    Institute of Scientific and Technical Information of China (English)

    Xianzeng Zhang; Xiaoyan Wang; Zhenlin Zhan; Qing Ye; Shusen Xie

    2009-01-01

    The feasibility of fenestration operation in middle ear bone with pulsed infrared laser is evaluated.Healthy male New Zealand rabbits in vivo are used in the experiment.Middle ear mastoid bone of animal model is complctely exposed with conventional methods,and then a pulsed CO2 laser(10.6 μm)and an Er:YAG laser(2.94 μm)are used to perform the fenestration operation.Diamond drill is also used as a control group.The total operation time and light irradiation time are recorded and the opening efficiency is assessed.The morphological changes and thermal damage around the opening window on the middle ear bone are examined.It is shown that both laser systems are suitable for the fenestration operation in middle ear bone,and this no-touch technique has a lot of benefits compared with traditional methods.The bleeding during operation has an important effect on operation time and thermal injury and needs to be controlled efficiently in further study.

  2. Development of a high energy pulsed plasma simulator for the study of liquid lithium trenches

    Energy Technology Data Exchange (ETDEWEB)

    Jung, S., E-mail: jung73@illinois.edu [Department of Nuclear, Plasma, and Radiological Engineering, University of Illinois at Urbana-Champaign, Urbana 61801 (United States); Christenson, M.; Curreli, D. [Department of Nuclear, Plasma, and Radiological Engineering, University of Illinois at Urbana-Champaign, Urbana 61801 (United States); Bryniarski, C. [Department of Electrical and Computer Engineering, University of Illinois at Urbana-Champaign, Urbana 61801 (United States); Andruczyk, D.; Ruzic, D.N. [Department of Nuclear, Plasma, and Radiological Engineering, University of Illinois at Urbana-Champaign, Urbana 61801 (United States)

    2014-12-15

    Highlights: • A pulse device for a liquid lithium trench study is developed. • It consists of a coaxial plasma gun, a theta pinch, and guiding magnets. • A large energy enhancement is observed with the use of the plasma gun. • A further increase in energy and velocity is observed with the theta pinch. - Abstract: To simulate detrimental events in a tokamak and provide a test-stand for a liquid-lithium infused trench (LiMIT) device [1], a pulsed plasma source utilizing a theta pinch in conjunction with a coaxial plasma accelerator has been developed. The plasma is characterized using a triple Langmuir probe, optical methods, and a calorimeter. Clear advantages have been observed with the application of a coaxial plasma accelerator as a pre-ionization source. The experimental results of the plasma gun in conjunction with the existing theta pinch show a significant improvement from the previous energy deposition by a factor of 14 or higher, resulting in a maximum energy and heat flux of 0.065 ± 0.002 MJ/m{sup 2} and 0.43 ± 0.01 GW/m{sup 2}. A few ways to further increase the plasma heat flux for LiMIT experiments are discussed.

  3. Simulation and experimental study of the solid pulse forming lines for dielectric wall accelerator

    Institute of Scientific and Technical Information of China (English)

    ZHAO Quan-Tang; YUAN Ping; ZHANG Zi-Min; CAO Shu-Chun; SHEN Xiao-Kang; LIU Ming; JING Yi; ZHAO Hong-Wei

    2011-01-01

    Two types of pulse forming lines for dielectric wall accelerator (DWA) were investigated preliminarily.By simulation with CST Microwave Studio,the results indicate the pulse forming process,which can help to understand the voltage wave transmission process and optimize the line parameters.Furthermore,the principle of the pulse forming process was proved by experiments and some excellent pulse waveforms were obtained.During the experiments,the Blumlein line and zero integral pulse (ZIP) forming line,constructed with aluminum foil,poly plate and air gap self-closing switch,were tested.The full width at half maximum (FWHM) of the waveform is 16 nanoseconds (BL) and 17 nanoseconds (ZIP line),and the formed pulse voltage amplitude is 5 kV (BL) and +2.2 kV/-1.6 kV (ZIP line).The experiments result coincides well with the simulation.

  4. Construction and temporal behaviour study of multi RLC intense light pulses for dermatological applications.

    Science.gov (United States)

    Hamoudi, Walid K; Ismail, Raid A; Shakir, Hussein A

    2017-10-01

    Driving a flash lamp in an intense pulsed light system requires a high-voltage DC power supply, capacitive energy storage and a flash lamp triggering unit. Single, double, triple and quadruple-mesh discharge and triggering circuits were constructed to provide intense light pulses of variable energy and time durations. The system was treated as [Formula: see text] circuit in some cases and [Formula: see text] circuit in others with a light pulse profile following the temporal behaviour of the exciting current pulse. Distributing the energy delivered to one lamp onto a number of LC meshes permitted longer current pulses, and consequently increased the light pulse length. Positive results were obtained when using the system to treat skin wrinkles.

  5. Effects of temporal laser profile on the emission spectra for underwater laser-induced breakdown spectroscopy: Study by short-interval double pulses with different pulse durations

    Energy Technology Data Exchange (ETDEWEB)

    Tamura, Ayaka, E-mail: tamura.ayaka.88m@st.kyoto-u.ac.jp; Matsumoto, Ayumu; Nishi, Naoya; Sakka, Tetsuo, E-mail: sakka.tetsuo.2a@kyoto-u.ac.jp [Department of Energy and Hydrocarbon Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 615-8510 (Japan); Nakajima, Takashi; Ogata, Yukio H. [Institute of Advanced Energy, Kyoto University, Uji, Kyoto 611-0011 (Japan); Fukami, Kazuhiro [Department of Materials Science and Engineering, Graduate School of Engineering, Kyoto University, Kyoto 606-8501 (Japan)

    2015-01-14

    We investigate the effects of temporal laser profile on the emission spectra of laser ablation plasma in water. We use short-interval (76 ns) double pulses with different pulse durations of the composing two pulses for the irradiation of underwater target. Narrow atomic spectral lines in emission spectra are obtained by the irradiation, where the two pulses are wide enough to be merged into a single-pulse-like temporal profile, while deformed spectra are obtained when the two pulses are fully separated. The behavior of the atomic spectral lines for the different pulse durations is consistent with that of the temporal profiles of the optical emission intensities of the plasma. All these results suggest that continuous excitation of the plasma during the laser irradiation for ∼100 ns is a key to obtain narrow emission spectral lines.

  6. Microstructural and Hardness Study of Pulsed Nd:YAG Laser Surface Alloyed Aluminum with Iron

    Science.gov (United States)

    Ansari, Mohammad; Soltani, Reza; Heydarzadeh Sohi, Mahmoud; Valefi, Zia

    2016-04-01

    In the present study, the feasibility of the formation of surface layers containing hard iron aluminides on AA6061-T6 aluminum via pre-plasma spraying with iron and subsequently double surface melting by pulsed Nd:YAG laser is studied. The effects of single and double laser surface melting on microstructure, phase formation, and hardness of the treated layers are examined. Single-step laser treatment resulted in the presence of undissolved iron particles surrounded by lump-like Al5Fe2 and needle-like Al3Fe intermetallic compounds. Double laser surface melting dissolved the retained undissolved irons and resulted in the formation of Al-Al3Fe eutectic structure. Microhardness profiles along cross section and top surface of the treated layers indicated that laser surface alloying with iron enhanced the hardness of the aluminum to more than twice of that of the base material.

  7. Study on SO2 Removal Efficiency by Nanosecond Rising Edge Pulse DBD Under Different Environmental Conditions

    Institute of Scientific and Technical Information of China (English)

    WANG Xiao-hua; SU Biao; LIU Ding-xin; WANG Jun-hua; RONG Ming-zhe

    2007-01-01

    In this paper,an experimental study on SO2 removal by nanosecond rising edge pulse dielectric barrier discharge (DBD) plasma,generated by multi-needle-to-plane electrodes,is carried out.The mechanism of the effect of various factors,such as gap size between dielectric barrier and discharge needles,environmental humidity,and inlet speed of gas flow upon the removal efficiency of air purification is analyzed.The studies show that SO2 removal efficiency improves with the increase in the gap size between dielectric barrier and discharge needles in the case of a fixed space between two electrodes,and also improves with the increase in the environmental humidity.For a mixed gas with a fixed concentration,there is an optimal inlet speed of gas flow,which leads to the best removal efficiency.

  8. Generation of pulsed Bessel-Gauss beams using passive axicon-theoretical and experimental studies.

    Science.gov (United States)

    Parsa, Shahrzad; Fallah, Hamid Reza; Ramezani, Mohsen; Soltanolkotabi, Mahmood

    2012-10-20

    We studied the conditions for generating passive Bessel-Gauss beams by using an axicon. We designed an appropriate Gaussian resonator and extracted a quasi-fundamental Gaussian mode from a pulsed Nd:YAG laser pumped by a Xenon flash lamp and measured its parameters, such as propagation factor, divergence angle, and Rayleigh range. Then we generated passive Bessel-Gauss beams using an axicon and investigated their propagation properties, theoretically and experimentally. For example, for the axicon of 1°, the output energy and the Rayleigh range of the generated Bessel-Gauss beams were measured to be 58 mJ and 229.3 mm, respectively. We compared these properties with our results of the Gaussian mode. Finally, by using axicons with different apex angles, and also by changing the beam spot size on the axicon, we generated Bessel-Gauss beams and studied their properties theoretically and experimentally.

  9. The reduction process of phytic acid-silver ion system: A pulse radiolysis study

    Energy Technology Data Exchange (ETDEWEB)

    Joshi, Ravi [Radiation and Photochemistry Division, Chemistry Group, Bhabha Atomic Research Center, Mumbai 400 085 (India)]. E-mail: rjudrin@yahoo.com; Mukherjee, Tulsi [Radiation and Photochemistry Division, Chemistry Group, Bhabha Atomic Research Center, Mumbai 400 085 (India)

    2007-05-15

    Reduction of silver ion in a silver-phytic acid (1:1 ratio) system has been studied using pulse radiolysis technique. Time-resolved transformation of the intermediates, Ag{sup +{yields}}Ag{sup 0{yields}}Ag{sub 2} {sup +{yields}}Ag{sub 3} {sup 2+}, has been clearly observed in the reduction of silver-phytic acid (1:1) system. The effect of phytic acid on the formation and decay of initial silver clusters has been also studied. The surface plasmon absorption band of stable silver nanoparticle (410 nm) and dynamic light scattering technique has been used to characterize the nanoparticles and measure the average size (R {sub av}=100 nm)

  10. Experimental Study of SO2 Removal by Pulsed DBD Along with the Application of Magnetic Field

    Institute of Scientific and Technical Information of China (English)

    RONG Ming-zhe; LIU Ding-xin; WANG Xiao-hua; WANG Jun-hua

    2007-01-01

    Dielectric barrier discharge (DBD) for SO2 removal from indoor air is investigated.In order to improve the removal efficiency,two novel methods are combined in this paper,namely by applying a pulsed driving voltage with nanosecond rising time and applying a magnetic field.For SO2 removal efficiency,different matches of electric field and magnetic field are discussed.And nanosecond rising edge pulsed power supply and microsecond rising edge pulsed power supply are compared.It can be concluded that a pulsed DBD with nanosecond rising edge should be adopted,and electrical field and magnetic field should be applied in an appropriate match.

  11. Study of 18-Pulse Rectifier Utilizing Hexagon Connected 3-Phase to 9-Phase Transformer

    Directory of Open Access Journals (Sweden)

    Ahmad Saudi Samosir

    2008-04-01

    Full Text Available The 18-pulse converter, using Y or -connected differential autotransformer, is very interesting since it allows natural high power factor correction. The lowest input current harmonic components are the 17th and 19th. The Transformer is designed to feed three six-pulse bridge rectifiers displaced in phase by 200. This paper present a high power factor three-phase rectifier bases on 3-phase to 9-phase transformer and 18-pulse rectifier. The 9-phase polygon-connected transformer followed by 18-pulse diode rectifiers ensures the fundamental concept of natural power factor correction. Simulation results to verify the proposed concept are shown in this paper.

  12. Pulse radiolysis studies on reactions of hydroxyl radicals with selenocystine derivatives.

    Science.gov (United States)

    Mishra, B; Kumbhare, L B; Jain, V K; Priyadarsini, K I

    2008-04-10

    Reactions of hydroxyl radicals (*OH) with selenocystine (SeCys) and two of its analogues, diselenodipropionic acid (SeP) and selenocystamine (SeA), have been studied in aqueous solutions at pHs of 1, 7, and 10 using the pulse radiolysis technique coupled with absorption detection. All of these diselenides react with *OH radicals with rate constants of approximately 10(10) M(-1) s(-1), producing diselenide radical cations ( approximately 1-5 micros after the pulse), with an absorption maximum at 560 nm, by elimination of H(2)O or OH(-) from hydroxyl radical adducts. Assignment of the 560 nm band to the diselenide radical cation was made by comparing the transient spectra with those produced upon reaction of diselenides with specific one-electron oxidants, Cl(2)(*-) (pH 1) and Br(2)(*-) radicals (pHs of 7 and 10). SeP having a carboxylic acid functionality showed quantitative conversion of hydroxyl radical adducts to radical cations. The compounds SeCys and SeA, having an amino functional group, in addition to the radical cations, produced a new transient with lambda(max) at 460 nm, at later time scales ( approximately 20-40 micros after the pulse). The rate and yield of formation of the 460 nm band increased with increasing concentrations of either SeCys or SeA. In analogy with similar studies reported for analogous disulfides, the 460 nm transient absorption band has been assigned to a triselenide radical adduct. The one-electron reduction potentials of the compounds were estimated to be 0.96, 1.3, and 1.6 V versus NHE, respectively, for SeP, SeCys, and SeA at pH 7. From these studies, it has been concluded that the electron-donating carboxylic acid group decreases the reduction potential and facilitates quantitative conversion of hydroxyl radical adducts to radical cations, while the electron-withdrawing NH(3)(+) group not only increases the reduction potential but also leads to fragmentation of the hydroxyl radical adduct to selenyl radicals, which are converted

  13. The association between pulse wave velocity and cognitive function: the Sydney Memory and Ageing Study.

    Directory of Open Access Journals (Sweden)

    Joel Singer

    Full Text Available OBJECTIVES: Pulse wave velocity (PWV is a measure of arterial stiffness and its increase with ageing has been associated with damage to cerebral microvessels and cognitive impairment. This study examined the relationship between carotid-femoral PWV and specific domains of cognitive function in a non-demented elderly sample. METHOD: Data were drawn from the Sydney Memory and Ageing Study, a cohort study of non-demented community-dwelling individuals aged 70-90 years, assessed in successive waves two years apart. In Wave 2, PWV and cognitive function were measured in 319 participants. Linear regression was used to analyse the cross-sectional relationship between arterial stiffness and cognitive function in the whole sample, and separately for men and women. Analysis of covariance was used to assess potential differences in cognition between subjects with PWV measurements in the top and bottom tertiles of the cohort. Covariates were age, education, body mass index, pulse rate, systolic blood pressure, cholesterol, depression, alcohol, smoking, hormone replacement therapy, apolipoprotein E ε4 genotype, use of anti-hypertensive medications, history of stroke, transient ischemic attack, myocardial infarction, angina, diabetes, and also sex for the whole sample analyses. RESULTS: There was no association between PWV and cognition after Bonferroni correction for multiple testing. When examining this association for males and females separately, an association was found in males, with higher PWV being associated with lower global cognition and memory, however, a significant difference between PWV and cognition between males and females was not found. CONCLUSION: A higher level of PWV was not associated with lower cognitive function in the whole sample.

  14. The Association between Pulse Wave Velocity and Cognitive Function: The Sydney Memory and Ageing Study

    Science.gov (United States)

    Singer, Joel; Trollor, Julian N.; Crawford, John; O’Rourke, Michael F.; Baune, Bernhard T.; Brodaty, Henry; Samaras, Katherine; Kochan, Nicole A.; Campbell, Lesley; Sachdev, Perminder S.; Smith, Evelyn

    2013-01-01

    Objectives Pulse wave velocity (PWV) is a measure of arterial stiffness and its increase with ageing has been associated with damage to cerebral microvessels and cognitive impairment. This study examined the relationship between carotid-femoral PWV and specific domains of cognitive function in a non-demented elderly sample. Method Data were drawn from the Sydney Memory and Ageing Study, a cohort study of non-demented community-dwelling individuals aged 70–90 years, assessed in successive waves two years apart. In Wave 2, PWV and cognitive function were measured in 319 participants. Linear regression was used to analyse the cross-sectional relationship between arterial stiffness and cognitive function in the whole sample, and separately for men and women. Analysis of covariance was used to assess potential differences in cognition between subjects with PWV measurements in the top and bottom tertiles of the cohort. Covariates were age, education, body mass index, pulse rate, systolic blood pressure, cholesterol, depression, alcohol, smoking, hormone replacement therapy, apolipoprotein E ε4 genotype, use of anti-hypertensive medications, history of stroke, transient ischemic attack, myocardial infarction, angina, diabetes, and also sex for the whole sample analyses. Results There was no association between PWV and cognition after Bonferroni correction for multiple testing. When examining this association for males and females separately, an association was found in males, with higher PWV being associated with lower global cognition and memory, however, a significant difference between PWV and cognition between males and females was not found. Conclusion A higher level of PWV was not associated with lower cognitive function in the whole sample. PMID:23637918

  15. Pilot Study: Estimation of Stroke Volume and Cardiac Output from Pulse Wave Velocity.

    Science.gov (United States)

    Obata, Yurie; Mizogami, Maki; Nyhan, Daniel; Berkowitz, Dan E; Steppan, Jochen; Barodka, Viachaslau

    2017-01-01

    Transesophageal echocardiography (TEE) is increasingly replacing thermodilution pulmonary artery catheters to assess hemodynamics in patients at high risk for cardiovascular morbidity. However, one of the drawbacks of TEE compared to pulmonary artery catheters is the inability to measure real time stroke volume (SV) and cardiac output (CO) continuously. The aim of the present proof of concept study was to validate a novel method of SV estimation, based on pulse wave velocity (PWV) in patients undergoing cardiac surgery. This is a retrospective observational study. We measured pulse transit time by superimposing the radial arterial waveform onto the continuous wave Doppler waveform of the left ventricular outflow tract, and calculated SV (SVPWV) using the transformed Bramwell-Hill equation. The SV measured by TEE (SVTEE) was used as a reference. A total of 190 paired SV were measured from 28 patients. A strong correlation was observed between SVPWV and SVTEE with the coefficient of determination (R2) of 0.71. A mean difference between the two (bias) was 3.70 ml with the limits of agreement ranging from -20.33 to 27.73 ml and a percentage error of 27.4% based on a Bland-Altman analysis. The concordance rate of two methods was 85.0% based on a four-quadrant plot. The angular concordance rate was 85.9% with radial limits of agreement (the radial sector that contained 95% of the data points) of ± 41.5 degrees based on a polar plot. PWV based SV estimation yields reasonable agreement with SV measured by TEE. Further studies are required to assess its utility in different clinical situations.

  16. Experimental study regarding the effects of pulsed short waves on nervous tissue

    Directory of Open Access Journals (Sweden)

    DOGARU Gabriela

    2014-05-01

    Full Text Available Pulsed short waves are part of high frequency therapy and have through their biological effects, the good therapeutic results and the lack of side effects many indications in various disorders: rheumatologic, traumatologic, burns, neurological (nerve tissue regeneration, ischemic vascular accidents, vascular disorders. The experimental study consisted of the exposure of laboratory animals to the action of pulsed short waves in different doses and the monitoring of changes in the brain cellular and subcellular structure. The study included 35 Wistar rats, assigned to four groups, three groups of 10 animals and the control group of five non-irradiated animals. Group I was exposed to a dose of 1/80 cycles/sec, group II to 4/400 cycles/sec, and group III to 6/600 cycles/sec, for 10 minutes/day, for 15 days. After the rats were sacrificed, nervous tissue fragments were collected. These were adequately processed for their examination by optical and electron microscopy. At structural level, in the control group and the groups exposed to the dose of 1/80 cycles/sec, the neurons were normally structured. In group II, a slight increase of brain metabolic activity was seen, in group III there was a significant increase of brain metabolism, with better myelinated white matter axons, which suggests a better protection for the rapid conduction of nerve impulses to effectors. In group II, electron microscopy revealed similar aspects to those of the control group. A high ribosome density was found in the neuroplasm, which means an intense protein synthesis process. In group III, there was an intense protein synthesis activity, and a strong axon myelination in the white matter, resulting in a better protection for the transmission of nerve impulses. Conclusions: pulsed short waves caused brain changes depending on the dose. The analysis of electron microscopic images showed that irradiation at a dose of 6/600 cycles/sec induced an intense protein synthesis

  17. Pulsed EPR and NMR spectroscopy of paramagnetic iron porphyrinates and related iron macrocycles: how to understand patterns of spin delocalization and recognize macrocycle radicals.

    Science.gov (United States)

    Walker, F Ann

    2003-07-28

    Pulsed EPR spectroscopic techniques, including ESEEM (electron spin echo envelope modulation) and pulsed ENDOR (electron-nuclear double resonance), are extremely useful for determining the magnitudes of the hyperfine couplings of macrocycle and axial ligand nuclei to the unpaired electron(s) on the metal as a function of magnetic field orientation relative to the complex. These data can frequently be used to determine the orientation of the g-tensor and the distribution of spin density over the macrocycle, and to determine the metal orbital(s) containing unpaired electrons and the macrocycle orbital(s) involved in spin delocalization. However, these studies cannot be carried out on metal complexes that do not have resolved EPR signals, as in the case of paramagnetic even-electron metal complexes. In addition, the signs of the hyperfine couplings, which are not determined directly in either ESEEM or pulsed ENDOR experiments, are often needed in order to translate hyperfine couplings into spin densities. In these cases, NMR isotropic (hyperfine) shifts are extremely useful in determining the amount and sign of the spin density at each nucleus probed. For metal complexes of aromatic macrocycles such as porphyrins, chlorins, or corroles, simple rules allow prediction of whether spin delocalization occurs through sigma or pi bonds, and whether spin density on the ligands is of the same or opposite sign as that on the metal. In cases where the amount of spin density on the macrocycle and axial ligands is found to be too large for simple metal-ligand spin delocalization, a macrocycle radical may be suspected. Large spin density on the macrocycle that is of the same sign as that on the metal provides clear evidence of either no coupling or weak ferromagnetic coupling of a macrocycle radical to the unpaired electron(s) on the metal, while large spin density on the macrocycle that is of opposite sign to that on the metal provides clear evidence of antiferromagnetic coupling

  18. Small plastic piston-cylinder cell for pulsed magnetic field studies at cryogenic temperatures

    Science.gov (United States)

    Coniglio, William A.; Graf, David E.; Tozer, Stanley W.

    2013-06-01

    A plastic piston-cylinder cell based on a thick wall test-tube has been designed for pulsed magnetic field studies. The small 12.7 mm diameter and overall height of 19.3 mm allow the cell to freely rotate in a cryostat with a diameter of 21.5 mm. Electrical leads, coax cable or microstrip transmission lines can be introduced into the pressure chamber for a variety of measurements such as electrical transport, de Haas-van Alphen, Shubnikov-de Haas and Hall effect. A fiber optic has been introduced for the purpose of calibrating the pressure via a ruby manometer. The fiber optic opens up additional experimental techniques such as photoluminescence, photoconductivity and, with use of a special fiber with a Bragg grating, magnetostriction and thermal expansion. Maximum pressures of 0.35 GPa at room temperature have been obtained.

  19. [Spectroscopic study on the high voltage fast pulsed discharge of nitrogen, ammonia or their mixture].

    Science.gov (United States)

    Liu, Z P; Wang, P N; Yang, W D; Zheng, J B; Li, F M

    2001-10-01

    The emission spectra from the pulsed discharge plasma of nitrogen, ammonia or their mixture were measured. In the discharge of pure nitrogen gas, as the pressure increased, the discharge volume decreased and more dissociation of nitrogen molecules occurred due to the higher energy density. In the discharge of ammonia, N,N+ and NH+ were observed, but no NH2 and NH3 were detected, indicating that ammonia, which has the lower dissociation and ionization energies as compared to nitrogen, was highly dissociated. The discharge of the mixture of N2 and NH3 was also studied. The dependence of the dissociation of nitrogen on the ratio of nitrogen to ammonia was investigated by emission spectra. The optimal ratio for nitrogen dissociation was obtained. The advantage of using the mixture of nitrogen and ammonia in the synthesis of nitrides was discussed.

  20. Studies on antioxidant enzymes in mice exposed to pulsed electromagnetic fields.

    Science.gov (United States)

    Eraslan, Gokhan; Bilgili, Ali; Akdogan, Mehmet; Yarsan, Ender; Essiz, Dinc; Altintas, Levent

    2007-02-01

    In this study, 56 female albino mice weighing 30-35 g were used. The animals were divided into a control and an experimental group. The animals in the experimental group were subjected to a pulsed electromagnetic field (PEMF) with a field magnitude of 50 Hz and 2 mT for 8h each day between 0900 and 1700 for 90 days. In both control and experimental groups, blood was sampled at 45, 60, and 90 days in heparinized tubes and erythrocyte malondialdehyde levels, and superoxide dismutase, glutathione peroxidase, catalase, and glucose-6-phosphate dehydrogenase activities were determined. The results revealed that the PEMF applied chronically within the given period and field magnitude does not cause oxidative damage.

  1. A study on scavenging effects of Chinese medicine on superoxide anion radicals by pulse radiolysis

    Energy Technology Data Exchange (ETDEWEB)

    Li Fengmei; Liu Andong; Gu Hongchun; Di Shaojie (Beijing Normal Univ., BJ (China). Inst. of Low Energy Nuclear Physics)

    A study on scavenging and dismutation effects on superoxide anion radical ([center dot]O[sub 2][sup -]) using two Chinese antiaging medicines - Salvia miltiorrhiza injection (S.M.) and Sulekang capsule (S.C.) was carried out using pulse radiolysis. The absorption spectra of [center dot] OH[sub 2][sup -] was redetermined by radiolysis of an aqueous solution of sodium format. The absorption maximum is at about 250 nm. The results suggested that S.M. and S.C. can dismutate and scavenge [center dot]O[sub 2][sup -]. The experimental scavenging rates of S.M. (150[mu]g/ml) and S.C. (250[mu]g/ml) were 89.6% and 69.5% respectively. (author).

  2. Modeling studies of a turbulent pulsed jet flame using LES/PDF

    Science.gov (United States)

    Zhang, Pei; Wang, Haifeng

    2015-11-01

    The combustion field in a pulsed turbulent piloted jet flame is studied using an advanced large eddy simulation (LES) / probability density function (PDF) method. Measurement data with a joint OH-PLIF/OH* chemiluminescence/LDV system are available including the temporal series of the axial velocity and planar OH images. A time-dependent inflow condition is specified based on the measurement data. A direct comparison of the mean and rms velocities from the calculations and from the measurement shows a satisfactory prediction of the flow fields by using the employed modeling methods. The predicted OH mass fractions are compared qualitatively with the measured OH images at selected temporal and spatial locations. The comparison shows a good agreement. Conditional quantities and flame index are extracted from the simulations to examine the bimodal and multi-regime combustion dynamics in the flame. This paper is based upon work supported by the National Science Foundation under Grant No. CBET-1336075.

  3. Direct optical observation of the formation of some aliphatic alcohol radicals. A pulse radiolysis study

    Indian Academy of Sciences (India)

    E Janata

    2002-12-01

    The kinetics of the reactions of hydroxyl radicals and hydrogen atoms with some aliphatic alcohols in aqueous solutions were studied using pulse radiolysis. Based on the increase in optical absorption in the UV region, the rate constants for the reaction of hydroxyl radicals and hydrogen atoms with methanol, ethanol, 2-propanol or -butyl alcohol were determined to be 9.0 × 108, 2.2 × 109, 2.0 × 109, 6.2 × 108 and 1.1 × 106, 1.8 × 107, 5.3 × 107, 2.3 × 105 dm3 mol-1 s-1 respectively. The bimolecular decay rate constants for the alcohol radicals produced in methanol and ethanol were evaluated to be 2 .4 × 109 and 1.5 × 109 dm3 mol-1 s-1. The values observed are in fairly good agreement with those reported earlier.

  4. Pulsed estrogen therapy in prevention of postmenopausal osteoporosis. A 2-year randomized, double blind, placebo-controlled study

    DEFF Research Database (Denmark)

    Nielsen, Therese F; Ravn, Pernille; Bagger, Yu Z

    2004-01-01

    The aim of this study was to evaluate the efficacy of pulsed estrogen therapy (intranasal 17beta-estradiol) in the prevention of postmenopausal bone loss. A total of 386 women (40-65 years old), less than 5 years past menopause, were randomized to intranasal placebo, 17beta-estradiol 150 micro g...... tolerance were good. This study demonstrates that pulsed estrogen therapy at the dose of 150 microg and 300-microg per day prevents bone loss in a dose-dependant manner at each site studied, and normalizes bone turnover markers to premenopausal levels....

  5. Experimental study of multiple-intermittent cryogen spurts and laser pulses for the treatment of port wine stain birthmarks

    Science.gov (United States)

    Aguilar, Guillermo; Choi, Bernard; Viator, John A.; Andersen, Dan; Nelson, J. Stuart

    2003-06-01

    Cryogen spray cooling (CSC) is used to minimize the risk of epidermal damage during pulsed laser treatment of port wine stain (PWS) birthmarks. Unfortunately, the current approach to CSC does not provide the necessary epidermal protection for all patients, particularly those with darker skin types. Therefore, alternative approaches need to be sought to improve PWS laser therapy. On a previous numerical study we showed that using multiple-intermittent CSC spurts and laser pulses could permit, under certain conditions, the use of higher laser doses while providing sufficient epidermal protection. In this study we show some results of ongoing experimental to study the feasibility of implementing clinically such an approach.

  6. Study on third-order nonlinear optical properties of 4-methylsulfanyl chalcone derivatives using picosecond pulses

    Energy Technology Data Exchange (ETDEWEB)

    D' silva, E.D., E-mail: deepak.dsilva@gmail.com [Department of Studies in Physics, Mangalore University, Mangalagangotri, Mangalore 574199 (India); Podagatlapalli, G. Krishna [Advanced Centre of Research in High Energy Materials (ACRHEM), University of Hyderabad, Hyderabad 500046 (India); Venugopal Rao, S., E-mail: soma_venu@yahoo.com [Advanced Centre of Research in High Energy Materials (ACRHEM), University of Hyderabad, Hyderabad 500046 (India); Dharmaprakash, S.M. [Department of Studies in Physics, Mangalore University, Mangalagangotri, Mangalore 574199 (India)

    2012-11-15

    Graphical abstract: Photograph and schematic representation of Z-scan experimental setup used to investigate third order nonlinear properties of the chalcone materials. Highlights: ► Br and NO{sub 2} substituted chalcone derivatives were exposed to picosecond laser pulses. ► Third-order nonlinear optical (NLO) properties were investigated. ► Compounds show promising third-order and optical limiting properties. ► These materials found suitable for electrical and optical applications. -- Abstract: In this paper we present results from the experimental study of third-order nonlinear optical (NLO) properties of three molecules of Br and NO{sub 2} substituted chalcone derivatives namely (2E)-1-(4-bromophenyl)-3-[4(methylsulfanyl)phenyl]prop-2-en-1-one (4Br4MSP), (2E)-1-(3-bromophenyl)-3-[4-(methylsulfanyl) phenyl]prop-2-en-1-one (3Br4MSP) and (2E)-3[4(methylsulfanyl) phenyl]-1-(4-nitrophenyl)prop-2-en-1-one (4N4MSP). The NLO properties have been investigated by Z-scan technique using 2 ps laser pulses at 800 nm. The nonlinear refractive indices, nonlinear absorption coefficient, and the magnitude of third-order susceptibility have been determined. The values obtained are of the order of 10{sup −7} cm{sup 2}/GW, 10{sup −3} cm/GW and 10{sup −14} esu respectively. The molecular second hyperpolarizability for the chalcone derivatives is of the order of 10{sup −32} esu. The coupling factor, excited state cross section, ground state cross section etc. were determined. The optical limiting (OL) property was studied. The results suggest that the nonlinear properties investigated for present chalcones are comparable with some of the reported chalcone derivatives and can be desirable for NLO applications.

  7. MR pulse sequences for selective relaxation time measurements: a phantom study

    DEFF Research Database (Denmark)

    Thomsen, C; Jensen, K E; Jensen, M

    1990-01-01

    a Siemens Magnetom wholebody magnetic resonance scanner operating at 1.5 Tesla was used. For comparison six imaging pulse sequences for relaxation time measurements were tested on the same phantom. The spectroscopic pulse sequences all had an accuracy better than 10% of the reference values....

  8. A study on matrix assisted pulsed evaporation (MAPLE) of organic materials

    DEFF Research Database (Denmark)

    Matei, Andreea; Canulescu, Stela; Constantinescu, Catalin

    2012-01-01

    Organic films can be produced either by MAPLE or directly by PLD (Pulsed laser deposition). For a reasonable deposition rate of ng/cm2 per pulse for film production by MAPLE a fluence of 1-1.5 J/cm2 is required at the laser wavelength of 355 nm, while the fluence can be considerably lower at 248 ...

  9. Principle study on the signal connection at transabdominal fetal pulse oximetry

    Directory of Open Access Journals (Sweden)

    Böttrich Marcel

    2016-09-01

    Full Text Available Transabdominal fetal pulse oximetry is an approach to measure oxygen saturation of the unborn child non-invasively. The principle of pulse oximetry is applied to the abdomen of a pregnant woman, such that the measured signal includes both, the maternal and the fetal pulse curve. One of the major challenges is to extract the shape of the fetal pulse curve from the mixed signal for computation of the oxygen saturation. In this paper we analyze the principle kind of connection of the fetal and maternal pulse curves in the measured signal. A time varying finite element model is used to rebuild the basic measurement environment, including a bulk tissue and two independently pulsing arteries to model the fetal and maternal blood circuit. The distribution of the light fluence rate in the model is computed by applying diffusion equation. From the detectors we extracted the time dependent fluence rate and analyzed the signal regarding its components. The frequency spectra of the signals show peaks at the fetal and maternal basic frequencies. Additional signal components are visible in the spectra, indicating multiplicative coupling of the fetal and maternal pulse curves. We conclude that the underlying signal model of algorithms for robust extraction of the shape of the fetal pulse curve, have to consider additive and multiplicative signal coupling.

  10. Nanosecond Pulsed Discharge in Water without Bubbles: A Fundamental Study of Initiation, Propagation and Plasma Characteristics

    Science.gov (United States)

    Seepersad, Yohan

    The state of plasma is widely known as a gas-phase phenomenon, but plasma in liquids have also received significant attention over the last century. Generating plasma in liquids however is theoretically challenging, and this problem is often overcome via liquid-gas phase transition preceding the actual plasma formation. In this sense, plasma forms in gas bubbles in the liquid. Recent work at the Drexel Plasma Institute has shown that nanosecond pulsed electric fields can initiate plasma in liquids without any initial cavitation phase, at voltages below theoretical direct-ionization thresholds. This unique regime is poorly understood and does not fit into any current descriptive mechanisms. As with all new phenomena, a complete fundamental description is paramount to understanding its usefulness to practical applications. The primary goals of this research were to qualitatively and quantitatively understand the phenomenon of nanosecond pulsed discharge in liquids as a means to characterizing properties that may open up niche application possibilities. Analysis of the plasma was based on experimental results from non-invasive, sub-nanosecond time-resolved optical diagnostics, including direct imaging, transmission imaging (Schlieren and shadow), and optical emission spectroscopy. The physical characteristics of the plasma were studied as a function of variations in the electric field amplitude and polarity, liquid permittivity, and pulse duration. It was found that the plasma size and emission intensity was dependent on the permittivity of the liquid, as well as the voltage polarity, and the structure and dynamics were explained by a 'cold-lightning' mechanism. The under-breakdown dynamics at the liquid-electrode interface were investigated by transmission imaging to provide evidence for a novel mechanism for initiation based on the electrostriction. This mechanism was proposed by collaborators on the project and developed alongside the experimental work in this

  11. Study on impurity desorption induced by femtosecond pulse laser based on a stochastic process model

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    With the advantages on non-equilibrium heating and desorption induced by electronic transition, the femtosecond pulse laser introduces a new way for solving the problem of impurity pollution adsorbed on a solid thin film in micro-electro-mechanical systems (MEMS). A model based on stochastic processes was established for stimulated desorption induced by the femtosecond pulse laser to interpret the interaction of the optically excited hot electrons with the adsorbed molecules in a metal substrate. Numerical simulation results reveal a time-dependent desorption probability of adsorbed molecules and indicate that how key parameters of femtosecond pulse laser, such as incident laser energy flux, pulse duration, and wavelength of pulse, have a great effect on the desorption probability.

  12. Validity and reproducibility of arterial pulse wave velocity measurement using new device with oscillometric technique: a pilot study.

    Science.gov (United States)

    Naidu, Madireddy Umamaheshwar Rao; Reddy, Budda Muralidhar; Yashmaina, Sridhar; Patnaik, Amar Narayana; Rani, Pingali Usha

    2005-08-23

    Availability of a range of techniques and devices allow measurement of many variables related to the stiffness of large or medium sized arteries. There is good evidence that, pulse wave velocity is a relatively simple measurement and is a good indicator of changes in arterial properties. The pulse wave velocity calculated from pulse wave recording by other methods like doppler or tonometry is tedious, time-consuming and above all their reproducibility depends on the operator skills. It requires intensive resource involvement. For epidemiological studies these methods are not suitable. The aim of our study was to clinically evaluate the validity and reproducibility of a new automatic device for measurement of pulse wave velocity that can be used in such studies. In 44 subjects including normal healthy control and patients with coronary artery disease, heart brachial, heart ankle, brachial ankle and carotid femoral pulse wave velocities were recorded by using a new oscillometric device. Lead I and II electrocardiogram and pressure curves were simultaneously recorded. Two observers recorded the pulse wave velocity for validation and one observer recorded the velocity on two occasions for reproducibility. Pulse wave velocity and arterial stiffness index were recorded in 24 control and 20 coronary artery disease patients. All the velocities were significantly high in coronary artery disease patients. There was highly significant correlation between the values noted by the two observers with low standard deviation. The Pearson's correlation coefficient for various velocities ranged from (r = 0.88-0.90) with (p wave velocity were also significantly correlated (r = 0.71-0.98) (P wave velocity was found to correlate significantly with heart brachial, heart ankle, brachial ankle pulse wave velocity and arterial stiffness index values. Reproducibility of our method was good with very low variability in both interobserver and interperiod analysis. The new device "Peri

  13. Analytical performances of laser-induced micro-plasma of Al samples with single and double ultrashort pulses in air and with Ar-jet: A comparative study

    Energy Technology Data Exchange (ETDEWEB)

    Semerok, A., E-mail: alexandre.semerok@cea.fr [CEA Saclay, DEN/DPC/SEARS/LISL, 91191 Gif-sur-Yvette (France); Dutouquet, C. [CEA Saclay, DEN/DPC/SEARS/LISL, 91191 Gif-sur-Yvette (France); INERIS/DRC/CARA/NOVA, F-60550 Verneuil En Halatte (France)

    2014-09-01

    Ultrashort pulse laser microablation coupled with optical emission spectroscopy was under study to obtain several micro-LIBS analytical features (shot-to-shot reproducibility, spectral line intensity and lifetime, calibration curves, detection limits). Laser microablation of Al matrix samples with known Cu- and Mg-concentrations was performed by single and double pulses of 50 fs and 1 ps pulse duration in air and with Ar-jet. The micro-LIBS analytical features obtained under different experimental conditions were characterized and compared. The highest shot-to-shot reproducibility and gain in plasma spectral line intensity were obtained with double pulses with Ar-jet for both 50 fs and 1 ps pulse durations. The best calibration curves were obtained with 1 ps pulse duration with Ar-jet. Micro-LIBS with ultrashort double pulses may find its effective application for surface elemental microcartography. - Highlights: • Analytical performances of micro-LIBS with ultrashort double pulses were studied. • The maximal line intensity gain of 20 was obtained with double pulses and Ar-jet. • LIBS gain was obtained without additional ablation of a sample by the second pulse. • LIBS properties were almost the same for both 50 fs and 1 ps pulses. • The micro-LIBS detection limit was around 35 ppm.

  14. Comparative study of CW, nanosecond- and femtosecond-pulsed laser microcutting of AZ31 magnesium alloy stents.

    Science.gov (United States)

    Gökhan Demir, Ali; Previtali, Barbara

    2014-06-01

    Magnesium alloys constitute an interesting solution for cardiovascular stents due to their biocompatibility and biodegradability in human body. Laser microcutting is the industrially accepted method for stent manufacturing. However, the laser-material interaction should be well investigated to control the quality characteristics of the microcutting process that concern the surface roughness, chemical composition, and microstructure of the final device. Despite the recent developments in industrial laser systems, a universal laser source that can be manipulated flexibly in terms of process parameters is far from reality. Therefore, comparative studies are required to demonstrate processing capabilities. In particular, the laser pulse duration is a key factor determining the processing regime. This work approaches the laser microcutting of AZ31 Mg alloy from the perspective of a comparative study to evaluate the machining capabilities in continuous wave (CW), ns- and fs-pulsed regimes. Three industrial grade machining systems were compared to reach a benchmark in machining quality, productivity, and ease of postprocessing. The results confirmed that moving toward the ultrashort pulse domain the machining quality increases, but the need for postprocessing remains. The real advantage of ultrashort pulsed machining was the ease in postprocessing and maintaining geometrical integrity of the stent mesh after chemical etching. Resultantly, the overall production cycle time was shortest for fs-pulsed laser system, despite the fact that CW laser system provided highest cutting speed.

  15. The Study of Active Atoms in High-Voltage Pulsed Coronal Discharge by Optical Diagnostics

    Institute of Scientific and Technical Information of China (English)

    Liu Feng; Wang Wenchun; Wang Su; Ren Chunsheng; Wang Younian

    2005-01-01

    In this study, the emission spectra of active atoms O (3p5P → 3s5S20 777.4 nm),Ha (3P → 2S 656.3 nm) and N (3p4P → 3s4S0 742.3 nm, 744.2 nm, 746.8 nm) produced by thepositive high-voltage pulsed corona discharge (HVPCD) of N2 and H2O mixture in a needle-platereactor have successfully been recorded against a severe electromagnetic interference coming fromthe HVPCD at one atmosphere. The effects of the peak voltage, the repetition rate of pulseddischarge and the flow rate of oxygen on the production of those active atoms are investigated. Itis found that when the peak voltage and the repetition rate of the pulsed discharge are increased,the emission intensities of those active atoms rise correspondingly. And the emission intensities ofO (3p5P → 3s5S20 777.4 nm), Ha (3P → 2S 656.3 nm) and N (3p4P → 3s4S0 742.3 nm, 744.2 nm,746.8 nm) increase with the flow rate of oxygen (from 0 to 25 ml/min) and achieve a maximumvalue at a flow rate of 25 ml/min. When the flow rate of oxygen is increased further, the emissionintensities of those atoms visibly decrease correspondingly. The main physicochemical processesof interaction involved between electrons, neutrals and ions are also discussed.

  16. Study of the inactivation of spoilage microorganisms in apple juice by pulsed light and ultrasound.

    Science.gov (United States)

    Ferrario, Mariana; Alzamora, Stella Maris; Guerrero, Sandra

    2015-04-01

    The aim of this study was to evaluate the effect of ultrasound (US) (600 W, 20 kHz and 95.2 μm wave amplitude; 10 or 30 min at 20, 30 or 44 ± 1 °C) and pulsed light (PL) (Xenon lamp; 3 pulses/s; 0.1 m distance; 2.4 J/cm(2)-71.6 J/cm(2); initial temperature 2, 30, 44 ± 1 °C) on the inactivation of Alicyclobacillus acidoterrestris ATCC 49025 spores and Saccharomyces cerevisiae KE162 inoculated in commercial (pH: 3.5; 12.5 °Brix) and natural squeezed (pH: 3.4; 11.8 °Brix) apple juices. Inactivation depended on treatment time, temperature, microorganism and matrix. Combination of these technologies led up to 3.0 log cycles of spore reduction in commercial apple juice and 2.0 log cycles in natural juice; while for S. cerevisiae, 6.4 and 5.8 log cycles of reduction were achieved in commercial and natural apple juices, respectively. In natural apple juice, the combination of US + 60 s PL at the highest temperature build-up (56 ± 1 °C) was the most effective treatment for both strains. In commercial apple juice, US did not contribute to further inactivation of spores, but significantly reduced yeast population. Certain combinations of US + PL kept on good microbial stability under refrigerated conditions for 15 days. Copyright © 2014 Elsevier Ltd. All rights reserved.

  17. Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure (letter)

    NARCIS (Netherlands)

    Wain, L.V.; Verwoert, G.C.; O'Reilly, P.F.; Shi, G.; Johnson, T.; Johnson, A.D.; Bochud, M.; Rice, K.M.; Henneman, P.; Smith, A.V.; Ehret, G.B.; Amin, N.; Larson, M.G.; Mooser, V.; Hadley, D.; Dorr, M.; Bis, J.C.; Aspelund, T.; Esko, T.; Janssens, A.C.J.W.; Zhao, J.H.; Heath, S.; Laan, M.; Fu, J.Y.; Pistis, G.; Luan, J.A.; Arora, P.; Lucas, G.; Pirastu, N.; Pichler, I.; Jackson, A.U.; Webster, R.J.; Zhang, F.; Peden, J.F.; Schmidt, H.; Tanaka, T.; Campbell, H.; Igl, W.; Milaneschi, Y.; Hottenga, J.J.; Vitart, V.; Chasman, D.I.; Trompet, S.; Bragg-Gresham, J.L.; Alizadeh, B.Z.; Chambers, J.C.; Guo, X.Q.; Lehtimaki, T.; Kuhnel, B.; Lopez, L.M.; Polasek, O.; Boban, M.; Nelson, C.P.; Morrison, A.C.; Pihur, V.; Ganesh, S.K.; Hofman, A.; Kundu, S.; Mattace-Raso, F.U.S.; Rivadeneira, F.; Sijbrands, E.J.G.; Uitterlinden, A.G.; Hwang, S.J.; Vasan, R.S.; Wang, T.J.; Bergmann, S.; Vollenweider, P.; Waeber, G.; Laitinen, J.; Pouta, A.; Zitting, P.; McArdle, W.L.; Kroemer, H.K.; Volker, U.; Volzke, H.; Glazer, N.L.; Taylor, K.D.; Harris, T.B.; Alavere, H.; Haller, T.; Keis, A.; Tammesoo, M.L.; Aulchenko, Y.; Barroso, I.; Khaw, K.T.; Galan, P.; Hercberg, S.; Lathrop, M.; Eyheramendy, S.; Org, E.; Sober, S.; Lu, X.W.; Nolte, I.M.; Penninx, B.W.; Corre, T.; Masciullo, C.; Sala, C.; Groop, L.; Voight, B.F.; Melander, O.; O'Donnell, C.J.; Salomaa, V.; d'Adamo, A.P.; Fabretto, A.; Faletra, F.; Ulivi, S.; Del Greco, M.F.; Facheris, M.; Collins, F.S.; Bergman, R.N.; Beilby, J.P.; Hung, J.; Musk, A.W.; Mangino, M.; Shin, S.Y.; Soranzo, N.; Watkins, H.; Goel, A.; Hamsten, A.; Gider, P.; Loitfelder, M.; Zeginigg, M.; Hernandez, D.; Najjar, S.S.; Navarro, P.; Wild, S.H.; Corsi, A.M.; Singleton, A.; de Geus, E.J.C.; Willemsen, G.; Parker, A.N.; Rose, L.M.; Buckley, B.; Stott, D.; Orru, M.; Uda, M.; van der Klauw, M.M.; Zhang, W.H.; Li, X.Z.; Scott, J.; Chen, Y.D.I.; Burke, G.L.; Kahonen, M.; Viikari, J.; Doring, A.; Meitinger, T.; Davies, G.; Starr, J.M.; Emilsson, V.; Plump, A.; Lindeman, J.H.; 'T Hoen, P.A.C.; Konig, I.R.; Felix, J.F.; Clarke, R.; Hopewell, J.C.; Ongen, H.; Breteler, M.; Debette, S.; DeStefano, A.L.; Fornage, M.; Mitchell, G.F.; Smith, N.L.; Holm, H.; Stefansson, K.; Thorleifsson, G.; Thorsteinsdottir, U.; Samani, N.J.; Preuss, M.; Rudan, I.; Hayward, C.; Deary, I.J.; Wichmann, H.E.; Raitakari, O.T.; Palmas, W.; Kooner, J.S.; Stolk, R.P.; Jukema, J.W.; Wright, A.F.; Boomsma, D.I.; Bandinelli, S.; Gyllensten, U.B.; Wilson, J.F.; Ferrucci, L.; Schmidt, R.; Farrall, M.; Spector, T.D.; Palmer, L.J.; Tuomilehto, J.; Pfeufer, A.; Gasparini, P.; Siscovick, D.; Altshuler, D.; Loos, R.J.F.; Toniolo, D.; Snieder, H.; Gieger, C.; Meneton, P.; Wareham, N.J.; Oostra, B.A.; Metspalu, A.; Launer, L.; Rettig, R.; Strachan, D.P.; Beckmann, J.S.; Witteman, J.C.M.; Erdmann, J.; van Dijk, K.W.; Boerwinkle, E.; Boehnke, M.; Ridker, P.M.; Jarvelin, M.R.; Chakravarti, A.; Abecasis, G.R.; Gudnason, V.; Newton-Cheh, C.; Levy, D.; Munroe, P.B.; Psaty, B.M.; Caulfield, M.J.; Rao, D.C.; Tobin, M.D.; Elliott, P.; van Duijn, C.M.

    2011-01-01

    Numerous genetic loci have been associated with systolic blood pressure (SBP) and diastolic blood pressure (DBP) in Europeans(1-3). We now report genome-wide association studies of pulse pressure (PP) and mean arterial pressure (MAP). In discovery (N = 74,064) and follow-up studies (N = 48,607), we

  18. Thermal degradation of two liquid fuels and detonation tests for pulse detonation engine studies

    Science.gov (United States)

    Rocourt, X.; Gillard, P.; Sochet, I.; Piton, D.; Prigent, A.

    2007-02-01

    The use of liquid fuels such as kerosene is of interest for the pulse detonation engine (PDE). Within this context, the aim of this work, which is a preliminary study, was to show the feasibility to initiate a detonation in air with liquid-fuel pyrolysis products, using energies and dimensions of test facility similars to those of PDEs. Therefore, two liquids fuels have been compared, JP10, which is a synthesis fuel generally used in the field of missile applications, and decane, which is one of the major components of standard kerosenes (F-34, Jet A1, ...). The thermal degradation of these fuels was studied with two pyrolysis processes, a batch reactor and a flow reactor. The temperatures varied from 600°C to 1,000°C and residence times for the batch reactor and the flow reactor were, respectively, between 10 30 s and 0.1 2 s. Subsequently, the detonability of synthetic gaseous mixtures, which was a schematisation of the decomposition state after the pyrolysis process, has been studied. The detonability study, regarding nitrogen dilution and equivalence ratio, was investigated in a 50 mm-diameter, 2.5 m-long detonation tube. These dimensions are compatible with applications in the aircraft industry and, more particularly, in PDEs. Therefore, JP10 and decane were compared to choose the best candidate for liquid-fuel PDE studies.

  19. Structural, morphological and Raman studies of pulse electrosynthesised indium antimonide thin films

    Energy Technology Data Exchange (ETDEWEB)

    Singh, Joginder, E-mail: joginderchauhan82@gmail.com; Chandel, Tarun; Rajaram, P. [School of Studies in Physics, Jiwaji University, Gwalior (MP), India-474011 (India)

    2015-08-28

    InSb films deposited on fluorine doped tin oxide (FTO) substrates by a pulse elctrodeposition technique. The deposition was carried out at an applied potential −1.3V versus Ag/AgCl electrode. Structural, morphological and optical studies were performed on the electrodeposited InSb. X-ray diffraction (XRD) studies show that the deposited InSb films are polycrystalline in nature having the zinc blend structure. The crystallite size (D), dislocation density (δ) and strain (ε) were calculated using XRD results. The EDAX analysis shows that chemical composition of In{sup 3+} and Sb{sup 3+} ions is close to the required stoichiometry. The surface morphology of the deposited films was examined using scanning electron microscopy (SEM). SEM studies reveal that the surface of the films is uniformly covered with submicron sized spherical particles. However, the crystallite size determined by the Scherrer method shows a size close to 30 nm. Surface morphology studies of the InSb films were also performed using atomic force microscopy (AFM). The average surface roughness as measured by AFM is around 40 nm. Hot probe studies show that all the electrodeposited thin films have n type conductivity and the thickness of the films is calculated using electrochemical formula.

  20. Responsive metal complexes: a click-based "allosteric scorpionate" complex permits the detection of a biological recognition event by EPR/ENDOR spectroscopy.

    Science.gov (United States)

    Tamanini, Emiliano; Rigby, Stephen E J; Motevalli, Majid; Todd, Matthew H; Watkinson, Michael

    2009-01-01

    Chemical sensing is a mature field, and many effective sensors for small anions and cations have been devised. Metal complexes have been used widely for this purpose, but there are fewer reports of their use in the detection of organic and biological analytes. To date metal complexes have been used in sensing via the direct displacement of a pre-existing ligand by an analyte, or by an adventitious complementarity between the complex and analyte. These strategies do not permit a general approach to the sensing of biological molecules with metal complexes because of the demands to engineer molecular recognition into the complex architecture. We describe a fundamentally new approach to this field-the "allosteric scorpionate" metal complex. The binding partner of a biological analyte is attached to a scorpionate ligand on a metal complex, remote from the metal centre. Binding of the analyte causes a change in the primary coordination sphere at the metal, thereby revealing the presence of the biological molecule. We show that azamacrocyclic complexes with a triazole scorpion ligand may be easily assembled with the [3+2] Huisgens 'click' cycloaddition. We demonstrate the synthesis of a biotin-functionalised cyclam derivative using this methodology. This, and our previously communicated zinc sensor, are to the best of our knowledge the first examples of a triazole being employed as a scorpion ligand on an azamacrocycle. Coordination by the triazole to the metal is perturbed by the binding of avidin to the pendant ligand. This event can be sensitively detected with EPR spectroscopy, and the details of the coordination change probed with ENDOR spectroscopy, confirming the loss of the axial triazole nitrogen donor upon binding to avidin. This represents the first metal complex where remote, 'allosteric' coordination of an analyte has been shown to cause a change in the primary coordination sphere of the metal. Since the synthesis is modular and straightforward, other

  1. The study of Zn–Co alloy coatings electrochemically deposited by pulse current

    Directory of Open Access Journals (Sweden)

    Tomić Milorad V.

    2012-01-01

    Full Text Available The electrochemical deposition by pulse current of Zn-Co alloy coatings on steel was examined, with the aim to find out whether pulse plating could produce alloys that could offer a better corrosion protection. The influence of on-time and the average current density on the cathodic current efficiency, coating morphology, surface roughness and corrosion stability in 3% NaCl was examined. At the same Ton/Toff ratio the current efficiency was insignificantly smaller for deposition at higher average current density. It was shown that, depending on the on-time, pulse plating could produce more homogenous alloy coatings with finer morphology, as compared to deposits obtained by direct current. The surface roughness was the greatest for Zn-Co alloy coatings deposited with direct current, as compared with alloy coatings deposited with pulse current, for both examined average current densities. It was also shown that Zn-Co alloy coatings deposited by pulse current could increase the corrosion stability of Zn-Co alloy coatings on steel. Namely, alloy coatings deposited with pulse current showed higher corrosion stability, as compared with alloy coatings deposited with direct current, for almost all examined cathodic times, Ton. Alloy coatings deposited at higher average current density showed greater corrosion stability as compared with coatings deposited by pulse current at smaller average current density. It was shown that deposits obtained with pulse current and cathodic time of 10 ms had the poorest corrosion stability, for both investigated average deposition current density. Among all investigated alloy coatings the highest corrosion stability was obtained for Zn-Co alloy coatings deposited with pulsed current at higher average current density (jav = 4 A dm-2.

  2. A comparative study of the bactericidal activity and daily disinfection housekeeping surfaces by a new portable pulsed UV radiation device.

    Science.gov (United States)

    Umezawa, Kazuo; Asai, Satomi; Inokuchi, Sadaki; Miyachi, Hayato

    2012-06-01

    Daily cleaning and disinfecting of non-critical surfaces in the patient-care areas are known to reduce the occurrence of health care-associated infections. However, the conventional means for decontamination of housekeeping surfaces of sites of frequent hand contact such as manual disinfection using ethanol wipes are laborious and time-consuming in daily practice. This study evaluated a newly developed portable pulsed ultraviolet (UV) radiation device for its bactericidal activity in comparison with continuous UV-C, and investigated its effect on the labor burden when implemented in a hospital ward. Pseudomonas aeruginosa, Multidrug-resistant P. aeruginosa, Escherichia coli, Acinetobacter baumannii, Amikacin and Ciprofloxacin-resistant A. baumannii, Staphylococcus aureus, Methicillin-resistant S. aureus and Bacillus cereus were irradiated with pulsed UV or continuous UV-C. Pulsed UV and continuous UV-C required 5 and 30 s of irradiation, respectively, to attain bactericidal activity with more than 2Log growth inhibition of all the species. The use of pulsed UV in daily disinfection of housekeeping surfaces reduced the working hours by half in comparison to manual disinfection using ethanol wipes. The new portable pulsed UV radiation device was proven to have a bactericidal activity against critical nosocomial bacteria, including antimicrobial-resistant bacteria after short irradiation, and was thus found to be practical as a method for disinfecting housekeeping surfaces and decreasing the labor burden.

  3. Experimental study on the single event latchup simulated by a pulse laser

    Institute of Scientific and Technical Information of China (English)

    Yang Shiyu; Cao Zhou; Li Danming; Xue Yuxiong; Tian Kai

    2009-01-01

    This paper introduces major characteristics of the single event latchup (SEL) in CMOS devices. We accomplish SEL tests for CPU and SRAM devices through the simulation by a pulse laser. The laser simulation results give the energy threshold for samples to undergo SEL. SEL current pulses are measured for CMOS devices in the latchup state, the sensitive areas in the devices are acquired, the major traits, causing large scale circuits to undergo SEL, are summarized, and the test equivalence between a pulse laser and ions is also analyzed.

  4. Experimental Study of Twin Pulse Jet Engines for Power Plant Application

    Institute of Scientific and Technical Information of China (English)

    Toshihiro Nakano; Shigeru Matsuo; Toshiaki Setoguchi; Shen Yu

    2003-01-01

    The total efficiency of power plants depends on the energy conversion in a combustor and a turbine. Considerably higher energy transfer rates can be obtained from a pulsed combustion, but unsteady flow of a single jet combustor reduces the turbine efficiency.Therefore, two pulse combustors were set in parallel and connected to a settling chamber that supplies a flow with constant pressure to the turbine.The aim of investigations presented here is a demonstration of technical feasibility for industrial applications and to show the benefits obtained from the pulse combustors.

  5. Filamentation of ultrashort laser pulses in silica glass and KDP crystal: A comparative study

    CERN Document Server

    Rolle, Jérémie; Duchateau, Guillaume; Skupin, Stefan

    2014-01-01

    Ionizing 800-nm femtosecond laser pulses propagating in silica glass and in potassium dihydrogen phosphate (KDP) crystal are investigated by means of a unidirectional pulse propagation code. Filamentation in fused silica is compared with the self-channeling of light in KDP accounting for the presence of defect states and electron-hole dynamics. In KDP, laser pulses produce intense filaments with higher clamping intensities up to 200 TW/cm$^2$ and longer plasma channels with electron densities above $10^{16}$ cm$^{-3}$. Despite these differences, the propagation dynamics in silica and KDP are almost identical at equivalent ratios of input power over the critical power for self-focusing.

  6. Experimental study on generation of high energy few cycle pulses with hollow fiber filled with neon

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    25 fs pulses with energy up to 0.8 mJ from a multi-pass amplifier system have been spectrally broadened from 460 nm to 950 nm due to strong self-phase modulation(SPM) effect in a gas filled hollow fiber.Using a set of chirped mirrors,the ul-tra-broadband dispersion compensation was achieved,and the compressed pulses reached their transform limit.Under optimized conditions we achieved pulses with duration of 5.1 fs and with energy of 400 μJ,corresponding to the peak power up to 80 GW.

  7. Experimental study on generation of high energy few cycle pulses with hollow fiber filled with neon

    Institute of Scientific and Technical Information of China (English)

    ZHU JiangFeng; WANG Peng; HAN HaiNian; TENG Hao; WEI ZhiYi

    2008-01-01

    25 fs pulses with energy up to 0.8 mJ from a multi-pass amplifier system have been spectrally broadened from 460 nm to 950 nm due to strong self-phase modulation (SPM) effect in a gas filled hollow fiber. Using a set of chirped mirrors, the ul-tra-broadband dispersion compensation was achieved, and the compressed pulses reached their transform limit. Under optimized conditions we achieved pulses with duration of 5.1 fs and with energy of 400 μJ, corresponding to the peak power up to 80 GW.

  8. Dynamic Experimental Study of a Multi—bypass Pulse Tube Refrigerator with Two—bypass Tubes

    Institute of Scientific and Technical Information of China (English)

    YonglinJu; ChaoWang; 等

    1998-01-01

    A dynamic experimental apparatus to measure the instantaneous velocity and pressure in the multibypass pulse tube refrigerator(MPTR) was designed and constructed.Some important experimental results of the instantaneous measurements of the velocity and the pressure in the MPTR with twobypass tubes during actual operation are prsented.The effects of the middle-bypass version on the dynamic pressure and mass flow rate at the cold end of the pulse tube are ev aluated from experimental measurements.DC-flow phenomena are observed in this MPTR.The reasons of the multi-bypass version improved the performance of pulse tube refrigertor are given.

  9. Radiation defect dynamics in Si at room temperature studied by pulsed ion beams

    Science.gov (United States)

    Wallace, J. B.; Charnvanichborikarn, S.; Bayu Aji, L. B.; Myers, M. T.; Shao, L.; Kucheyev, S. O.

    2015-10-01

    The evolution of radiation defects after the thermalization of collision cascades often plays the dominant role in the formation of stable radiation disorder in crystalline solids of interest to electronics and nuclear materials applications. Here, we explore a pulsed-ion-beam method to study defect interaction dynamics in Si crystals bombarded at room temperature with 500 keV Ne, Ar, Kr, and Xe ions. The effective time constant of defect interaction is measured directly by studying the dependence of lattice disorder, monitored by ion channeling, on the passive part of the beam duty cycle. The effective defect diffusion length is revealed by the dependence of damage on the active part of the beam duty cycle. Results show that the defect relaxation behavior obeys a second order kinetic process for all the cases studied, with a time constant in the range of ˜4-13 ms and a diffusion length of ˜15-50 nm. Both radiation dynamics parameters (the time constant and diffusion length) are essentially independent of the maximum instantaneous dose rate, total ion dose, and dopant concentration within the ranges studied. However, both the time constant and diffusion length increase with increasing ion mass. This demonstrates that the density of collision cascades influences not only defect production and annealing efficiencies but also the defect interaction dynamics.

  10. EMPulse, a new 3-D simulation code for electromagnetic pulse studies

    Science.gov (United States)

    Cohen, Bruce; Eng, Chester; Farmer, William; Friedman, Alex; Grote, David; Kruger, Hans; Larson, David

    2016-10-01

    EMPulse is a comprehensive and modern 3-D simulation code for electro-magnetic pulse (EMP) formation and propagation studies, being developed at LLNL as part of a suite of codes to study E1 EMP originating from prompt gamma rays. EMPulse builds upon the open-source Warp particle-in-cell code framework developed by members of this team and collaborators at other institutions. The goal of this endeavor is a new tool enabling the detailed and self-consistent study of multi-dimensional effects in geometries that have typically been treated only approximately. Here we present an overview of the project, the models and methods that have been developed and incorporated into EMPulse, tests of these models, comparisons to simulations undertaken in CHAP-lite (derived from the legacy code CHAP due to C. Longmire and co-workers), and some approaches to increased computational efficiency being studied within our project. This work was performed under the auspices of the U.S. DOE by Lawrence Livermore National Security, LLC, Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344.

  11. Application of double pulse theory for hemispherical microelectrodes to the experimental study of slow charge transfer processes

    Energy Technology Data Exchange (ETDEWEB)

    Laborda, Eduardo [Departamento de Quimica Fisica, Universidad de Murcia, Espinardo 30100, Murcia (Spain); Rogers, Emma I. [Department of Chemistry, Physical and Theoretical Chemistry Laboratory, Oxford University, South Parks Road, Oxford OX1 3QZ (United Kingdom); Martinez-Ortiz, Francisco [Departamento de Quimica Fisica, Universidad de Murcia, Espinardo 30100, Murcia (Spain); Molina, Angela, E-mail: amolina@um.e [Departamento de Quimica Fisica, Universidad de Murcia, Espinardo 30100, Murcia (Spain); Compton, Richard G., E-mail: richard.compton@chem.ox.ac.u [Department of Chemistry, Physical and Theoretical Chemistry Laboratory, Oxford University, South Parks Road, Oxford OX1 3QZ (United Kingdom)

    2010-09-01

    Differential Pulse Voltammetry and Reverse Pulse Voltammetry are applied to the study of the electrode kinetics of slow charge transfer processes at hemispherical microelectrodes of ca. 25 {mu}m radius. The electrochemical reversibility of three redox systems: 3-nitrophenolate{sup -/2-{center_dot}}, 3-nitrophthalate{sup 2-/3-{center_dot}} and europium{sup 3+/2+}, are evaluated with both techniques by determining the heterogeneous rate constant, the electron transfer coefficient as well as the formal potential for each. The experimental results show the value of these techniques for the characterization of the electrode kinetics by means of simple diagnostic criteria and single-point fit to general working curves. Further, theory developed for double potential pulse under radial diffusion conditions is validated.

  12. Development and application of resistive pulse spectroscopy: studies on the size, form and deformability of red blood cells

    Energy Technology Data Exchange (ETDEWEB)

    Yee, J.P.

    1979-01-01

    The following studies were conducted using the resistive pulse spectroscopy (RPS) technique: cumulative spectra and individual pulse forms for rigid latex polymer spheres; acquisition and analysis of RPS spectral data by means of special computer program; interaction of red blood cells with glutaraldehyde; membrane properties of erythrocytes undergoing abrupt osmotic hemolysis; reversible effects of the binding of chlorpromazine HCl at the red cell membrane surface; effects of high cholesterol diet on erythrocytes of guinea pigs; and multi-population analysis for a mixture of fetal and maternal red cells. (HLW)

  13. Numerical and experimental studies of mechanisms underlying the effect of pulsed broadband terahertz radiation on nerve cells

    Energy Technology Data Exchange (ETDEWEB)

    Duka, M V; Dvoretskaya, L N; Babelkin, N S; Khodzitskii, M K; Chivilikhin, S A; Smolyanskaya, O A [St. Petersburg National Research University of Information Technologies, Mechanics and Optics, St. Petersburg (Russian Federation)

    2014-08-31

    We have studied the mechanisms underlying the effect of pulsed broadband terahertz radiation on the growth of neurites of sensory ganglia using a comparative analysis of measured reflection spectra of ganglion neurites (in the frequency range 0.1 – 2.0 THz) and spectra obtained by numerical simulation with CST Microwave Studio. The observed changes are shown to be mainly due to pulse energy absorption in the ganglion neurites. Of particular interest are the observed single resonance frequencies related to resonance size effects, which can be used to irradiate ganglia in order to activate their growth. (laser biophotonics)

  14. Urinary (1)H Nuclear Magnetic Resonance Metabolomic Fingerprinting Reveals Biomarkers of Pulse Consumption Related to Energy-Metabolism Modulation in a Subcohort from the PREDIMED study.

    Science.gov (United States)

    Madrid-Gambin, Francisco; Llorach, Rafael; Vázquez-Fresno, Rosa; Urpi-Sarda, Mireia; Almanza-Aguilera, Enrique; Garcia-Aloy, Mar; Estruch, Ramon; Corella, Dolores; Andres-Lacueva, Cristina

    2017-04-07

    Little is known about the metabolome fingerprint of pulse consumption. The study of robust and accurate biomarkers for pulse dietary assessment has great value for nutritional epidemiology regarding health benefits and their mechanisms. To characterize the fingerprinting of dietary pulses (chickpeas, lentils, and beans), spot urine samples from a subcohort from the PREDIMED study were stratified using a validated food frequency questionnaire. Urine samples of nonpulse consumers (≤4 g/day of pulse intake) and habitual pulse consumers (≥25 g/day of pulse intake) were analyzed using a (1)H nuclear magnetic resonance (NMR) metabolomics approach combined with multi- and univariate data analysis. Pulse consumption showed differences through 16 metabolites coming from (i) choline metabolism, (ii) protein-related compounds, and (iii) energy metabolism (including lower urinary glucose). Stepwise logistic regression analysis was applied to design a combined model of pulse exposure, which resulted in glutamine, dimethylamine, and 3-methylhistidine. This model was evaluated by a receiver operating characteristic curve (AUC > 90% in both training and validation sets). The application of NMR-based metabolomics to reported pulse exposure highlighted new candidates for biomarkers of pulse consumption and the impact on energy metabolism, generating new hypotheses on energy modulation. Further intervention studies will confirm these findings.

  15. Systematic study of spatiotemporal dynamics of intense femtosecond laser pulses in BK-7 glass

    Indian Academy of Sciences (India)

    Ram Gopal; V Deepak; S Sivaramakrishnan

    2007-04-01

    In this paper we present a systematic study of the spatial and temporal effects of intense femtosecond laser pulses in BK-7 over a broad range of input powers, 1–1000 times the critical power for self-focusing (cr) by numerically solving the nonlinear Schrödinger equation (NLS). Most numerical studies have not been extended to such high powers. A clear-cut classification of spatio-temporal dynamics up to very high powers into three regimes – the group-velocity dispersion (GVD) regime, the ionization regime and the dominant plasma regime – as done here, is a significant step towards a better understanding. Further, we examine in detail the role of GVD in channel formation by comparing BK-7 to an `artificial' medium. Our investigations bring forth the important observation that diffraction plays a minimal role in the formation of multiple cones and that plasma plays a diffraction-like role at very high powers. A detailed study of the spatio-temporal dynamics in any condensed medium over this range of powers has not been reported hitherto, to the best of our knowledge. We also suggest appropriate operational powers for various applications employing BK-7 on the basis of our results.

  16. Morphological and Electrochemical Study of Sulfide/Nitride Nanostructure Deposited Through Pulsed Plasma Electrolysis

    Science.gov (United States)

    Tavakoli, H.; Sobhani, M.

    2017-04-01

    This study investigated the feasibility of coating a steel St12 substrate with a sulfide/nitride layer. The coating process was conducted through a plasma electrolysis technique with a pulsed regime applied at frequencies of 100, 500, and 1000 Hz. It was found that the use of higher frequencies in the mentioned process provides better control over workpiece surface temperature and leads to reduced extent of voltage variations required to achieve a fixed temperature. The coating deposited at the frequency of 1000 Hz and voltage of about 235 V exhibited a nanostructure composed of 50 nm particles. The deposited coating consisted of an outer porous layer and an inner relatively dense layer. The x-ray studies identified the phases of the coating as γ'-Fe4N, Fe2-3N and FeS. The presence of FeS phase reduces the friction coefficient of the surface to about half the value obtainable in its absence. Studying the electrochemical impedance of the layer revealed that using a higher frequency in the deposition process increases the stability of resulting layer against seven days of immersion in the corrosive solution.

  17. Pulsed lasers versus continuous light sources in capillary electrophoresis and fluorescence detection studies: Photodegradation pathways and models.

    Science.gov (United States)

    Boutonnet, Audrey; Morin, Arnaud; Petit, Pierre; Vicendo, Patricia; Poinsot, Véréna; Couderc, François

    2016-03-17

    Pulsed lasers are widely used in capillary electrophoresis (CE) studies to provide laser induced fluorescence (LIF) detection. Unfortunately pulsed lasers do not give linear calibration curves over a wide range of concentrations. While this does not prevent their use in CE/LIF studies, the non-linear behavior must be understood. Using 7-hydroxycoumarin (7-HC) (10-5000 nM), Tamra (10-5000 nM) and tryptophan (1-200 μM) as dyes, we observe that continuous lasers and LEDs result in linear calibration curves, while pulsed lasers give polynomial ones. The effect is seen with both visible light (530 nm) and with UV light (355 nm, 266 nm). In this work we point out the formation of byproducts induced by pulsed laser upon irradiation of 7-HC. Their separation by CE using two Zeta LIF detectors clearly shows that this process is related to the first laser detection. All of these photodegradation products can be identified by an ESI-/MS investigation and correspond to at least two 7HC dimers. By using the photodegradation model proposed by Heywood and Farnsworth (2010) and by taking into account the 7-HC results and the fact that in our system we do not have a constant concentration of fluorophore, it is possible to propose a new photochemical model of fluorescence in LIF detection. The model, like the experiment, shows that it is difficult to obtain linear quantitation curves with pulsed lasers while UV-LEDs used in continuous mode have this advantage. They are a good alternative to UV pulsed lasers. An application involving the separation and linear quantification of oligosaccharides labeled with 2-aminobezoic acid is presented using HILIC and LED (365 nm) induced fluorescence. Copyright © 2016 Elsevier B.V. All rights reserved.

  18. The theory study of Metal absorptivity in femtosecond pulsed laser ablation

    Institute of Scientific and Technical Information of China (English)

    LI Li; ZHANG Duan-ming; LI Zhi-hua; TAN Xin-yu; FANG Ran-ran

    2007-01-01

    In this paper,the effect of the absorptivity of metal on femtosecond pulsed laser ablation is investigated.The formulas for the absorptivity depending on target temperature are derived from Maxwell Equations and the Lambert-Beer's law.Based on this,a new two-temperature model is proposed to describe the femtosecond pulsed laser ablation with metal.Then,using Au as an example,a finite difference method is employed to simulate the space-dependent and time-dependent absorptivity and the target temperature.The temperature evolution of our model is compared with the result obtained form the heat conduction model taking the absorptivity as constant.It is shown that the absorptivity plays an important role in the femtosecond pulsed laser ablation.The results of this paper are helpful in choosing the best technical parameters in femtosecond pulsed laser ablation.

  19. Kinetics study of the solvated electron decay in THF using laser-synchronised picosecond electron pulse

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Picosecond pulse radiolysis of neat tetrahydrofuran (THF) shows a fast decay of the solvated electron within 2.5ns. The decay of the solvated electron observed at 790nm is because of spur reaction. A numerical simulation using time dependent Smoluchowski equation containing a sink term with a distance dependent reaction rate is used to fit the pulse-probe data and shows that the geminate reaction can proceed at long distance in this low polar solvent.

  20. Simulation study on thermal effect of long pulse laser interaction with CFRP material

    Science.gov (United States)

    Ma, Yao; Jin, Guangyong; Yuan, Boshi

    2016-10-01

    Laser machining is one of most widely used technologies nowadays and becoming a hot industry as well. At the same time, many kinds of carbon fiber material have been used in different area, such as sports products, transportation, microelectronic industry and so on. Moreover, there is lack of the combination research on the laser interaction with Carbon Fiber Reinforced Polymer (CFRP) material with simulation method. In this paper, the temperature status of long pulse laser interaction with CFRP will be simulated and discussed. Firstly, a laser thermal damage model has been built considering the heat conduction theory and thermal-elasto-plastic theory. Then using COMSOL Multiphysics software to build the geometric model and to simulate the mathematic results. Secondly, the functions of long pulse laser interaction with CFRP has been introduced. Material surface temperature increased by time during the laser irradiating time and the increasing speed is faster when the laser fluence is higher. Furthermore, the peak temperature of the center of material surface is increasing by enhanced the laser fluence when the pulse length is a constant value. In this condition, both the ablation depth and the Heat Affected Zone(HAZ) is larger when increased laser fluence. When keep the laser fluence as a constant value, the laser with shorter pulse length is more easier to make the CFRP to the vaporization material. Meanwhile, the HAZ is becoming larger when the pulse length is longer, and the thermal effect depth is as the same trend as the HAZ. As a result, when long pulse laser interaction with CFRP material, the thermal effect is the significant value to analysis the process, which is mostly effect by laser fluence and pulse length. For laser machining in different industries, the laser parameter choose should be different. The shorter pulse length laser is suitable for the laser machining which requires high accuracy, and the longer one is better for the deeper or larger

  1. SOLID BODY ABLATION UNDER EXPOSURE TO ULTRA SHORT LASER PULSES: STUDY BY MOLECULAR DYNAMICS METHODS

    Directory of Open Access Journals (Sweden)

    D. S. Ivanov

    2014-09-01

    Full Text Available The process of laser ablation under the influence of ultra short laser pulses on metals is investigated by methods of molecular dynamics. The validity and applicability of the hybrid atomistic-continuous model for the estimation of optimum modes of ultra short laser pulses processing are explored. Combination of atomistic model of laser-induced non-equilibrium process of a phase transition at the atomic level with continuous two-temperature model for describing the dynamics of photo-excitation of free media is proposed. Applicability of laser ablation model on the example of aluminum films and gold under exposure to pulses with different energy density and duration is shown. It is indicated that, depending on the ratio of the laser pulse duration and the characteristic time of electron-phonon material interaction, photothermal and photomechanical modes of destruction are implemented that determine the quality and performance of the laser processing. It is established that at the duration of laser pulse less than the time of electron-phonon interaction high-performance photomechanical type of destruction is implemented by internal stresses arising in the area of exposure. This is confirmed by a linear dependence of the ablation rate from the absorbed energy. At the duration of laser pulse greater than the time of electron-phonon interaction inefficient photothermal mode of destruction is implemented. The results may be useful for specialists engaged in the development of laser technologies

  2. Experimental study of a valveless pulse detonation rocket engine using nontoxic hypergolic propellants

    Science.gov (United States)

    Kan, Brandon K.

    A pulsed detonation rocket engine concept was explored through the use of hypergolic propellants in a fuel-centered pintle injector combustor. The combustor design yielded a simple open ended chamber with a pintle type injection element and pressure instrumentation. High-frequency pressure measurements from the first test series showed the presence of large pressure oscillations in excess of 2000 psia at frequencies between 400-600 hz during operation. High-speed video confirmed the high-frequency pulsed behavior and large amounts of after burning. Damaged hardware and instrumentation failure limited the amount of data gathered in the first test series, but the experiments met original test objectives of producing large over-pressures in an open chamber. A second test series proceeded by replacing hardware and instrumentation, and new data showed that pulsed events produced under expanded exhaust prior to pulsing, peak pressures around 8000 psi, and operating frequencies between 400-800 hz. Later hot-fires produced no pulsed behavior despite undamaged hardware. The research succeeded in producing pulsed combustion behavior using hypergolic fuels in a pintle injector setup and provided insights into design concepts that would assist future injector designs and experimental test setups.

  3. Temperature dependent photoreflectance study of Cu2SnS3 thin films produced by pulsed laser deposition

    DEFF Research Database (Denmark)

    Raadik, T.; Grossberg, M.; Krustok, J.

    2017-01-01

    The energy band structure of Cu2SnS3 (CTS) thin films fabricated by pulsed laser deposition was studied by photoreflectance spectroscopy (PR). The temperature-dependent PR spectra were measured in the range of T = 10–150 K. According to the Raman scattering analysis, the monoclinic crystal...

  4. Circadian response reduction in light and response restoration in darkness : A "Skeleton" light pulse PRC study in mice (Mus musculus)

    NARCIS (Netherlands)

    Comas, M.; Beersma, D. G. M.; Spoelstra, K.; Daan, S.

    2007-01-01

    Entrainment may involve responses to dawn, to dusk, and to the light in between these transitions. Previous studies showed that the circadian system responds to only 2 light pulses, one at the beginning and one at the end of the day, in a similar way as to a full photoperiod, as long as the photoper

  5. Circadian response reduction in light and response restoration in darkness : A "Skeleton" light pulse PRC study in mice (Mus musculus)

    NARCIS (Netherlands)

    Comas, M.; Beersma, D. G. M.; Spoelstra, K.; Daan, S.

    2007-01-01

    Entrainment may involve responses to dawn, to dusk, and to the light in between these transitions. Previous studies showed that the circadian system responds to only 2 light pulses, one at the beginning and one at the end of the day, in a similar way as to a full photoperiod, as long as the

  6. Pulse radiolytic studies of electron transfer processes and applications to solar photochemistry. Progress report, [March 1992--March 1993

    Energy Technology Data Exchange (ETDEWEB)

    Neta, P.

    1993-04-01

    Electron transfer and other reactions of various short-lived intermediates have been studied by pulse radiolysis and laser flash photolysis. Highlights of results during the past year are summarized under two main sections: Metalloporphyrin electron transfer and associated reactions, and solvent effects on reactions of inorganic radicals and organic peroxyl radicals.

  7. Numerical studies of wall-plasma interactions and ionization phenomena in an ablative pulsed plasma thruster

    Science.gov (United States)

    Yang, Lei; Zeng, Guangshang; Tang, Haibin; Huang, Yuping; Liu, Xiangyang

    2016-07-01

    Wall-plasma interactions excited by ablation controlled arcs are very critical physical processes in pulsed plasma thrusters (PPTs). Their effects on the ionization processes of ablated vapor into discharge plasma directly determine PPT performances. To reveal the physics governing the ionization phenomena in PPT discharge, a modified model taking into account the pyrolysis effect of heated polytetrafluoroethylene propellant on the wall-plasma interactions was developed. The feasibility of the modified model was analyzed by creating a one-dimensional simulation of a rectangular ablative PPT. The wall-plasma interaction results based on this modified model were found to be more realistic than for the unmodified model; this reflects the dynamic changes of the inflow parameters during discharge in our model. Furthermore, the temporal and spatial variations of the different plasma species in the discharge chamber were numerically studied. The numerical studies showed that polytetrafluoroethylene plasma was mainly composed of monovalent ions; carbon and fluorine ions were concentrated in the upstream and downstream discharge chamber, respectively. The results based on this modified model were in good agreement with the experimental formation times of the various plasma species. A large number of short-lived and highly ionized carbon and fluorine species (divalent and trivalent ions) were created during initial discharge. These highly ionized species reached their peak density earlier than the singly ionized species.

  8. The Effects of Pulsed Electromagnetic Field in the Treatment of Osteoarthritis in Dogs: Clinical Study

    Directory of Open Access Journals (Sweden)

    Stefania Pinna*§, Francesca Landucci§, Anna Maria Tribuiani§, Fabio Carli and Antonio Venturini

    2013-01-01

    Full Text Available In this study the effects of pulsed electromagnetic field (PEMF on pain relief and functional capacity of dogs with osteoarthritis (OA were investigated, and compared with firocoxib. Patients were randomly assigned to two groups: twenty-five client-owned dogs were treated with PEMF once a day for 20 sessions, and fifteen dogs (control group were treated with 5 mg/kg of firocoxib once daily for 20 days. Blinded clinical examination and owner’s assessment were recorded before and after the therapy, as well as 4 and 12 months later. Data collections were statistically compared before and after treatments and between groups. Both groups showed decreased clinical signs of OA during the treatment. Compared with baseline, these improvements were statistically significant (P<0.01 during the therapies. Differences were recorded during observation time spans following the end of treatments. In the PEMF group the effects were sustained until the end of the study, whereas in the control group the progress tended to return to baseline values after the end of therapy. The beneficial effects of PEMF on pain relief and functional capacity make it a potential treatment modality for canine osteoarthritis compared to traditional pharmacological therapy, in absence of adverse effects and in favour of the quality of life.

  9. Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

    Science.gov (United States)

    Wain, Louise V; Verwoert, Germaine C; O’Reilly, Paul F; Shi, Gang; Johnson, Toby; Johnson, Andrew D; Bochud, Murielle; Rice, Kenneth M; Henneman, Peter; Smith, Albert V; Ehret, Georg B; Amin, Najaf; Larson, Martin G; Mooser, Vincent; Hadley, David; Dörr, Marcus; Bis, Joshua C; Aspelund, Thor; Esko, Tõnu; Janssens, A Cecile JW; Zhao, Jing Hua; Heath, Simon; Laan, Maris; Fu, Jingyuan; Pistis, Giorgio; Luan, Jian’an; Arora, Pankaj; Lucas, Gavin; Pirastu, Nicola; Pichler, Irene; Jackson, Anne U; Webster, Rebecca J; Zhang, Feng; Peden, John F; Schmidt, Helena; Tanaka, Toshiko; Campbell, Harry; Igl, Wilmar; Milaneschi, Yuri; Hotteng, Jouke-Jan; Vitart, Veronique; Chasman, Daniel I; Trompet, Stella; Bragg-Gresham, Jennifer L; Alizadeh, Behrooz Z; Chambers, John C; Guo, Xiuqing; Lehtimäki, Terho; Kühnel, Brigitte; Lopez, Lorna M; Polašek, Ozren; Boban, Mladen; Nelson, Christopher P; Morrison, Alanna C; Pihur, Vasyl; Ganesh, Santhi K; Hofman, Albert; Kundu, Suman; Mattace-Raso, Francesco US; Rivadeneira, Fernando; Sijbrands, Eric JG; Uitterlinden, Andre G; Hwang, Shih-Jen; Vasan, Ramachandran S; Wang, Thomas J; Bergmann, Sven; Vollenweider, Peter; Waeber, Gérard; Laitinen, Jaana; Pouta, Anneli; Zitting, Paavo; McArdle, Wendy L; Kroemer, Heyo K; Völker, Uwe; Völzke, Henry; Glazer, Nicole L; Taylor, Kent D; Harris, Tamara B; Alavere, Helene; Haller, Toomas; Keis, Aime; Tammesoo, Mari-Liis; Aulchenko, Yurii; Barroso, Inês; Khaw, Kay-Tee; Galan, Pilar; Hercberg, Serge; Lathrop, Mark; Eyheramendy, Susana; Org, Elin; Sõber, Siim; Lu, Xiaowen; Nolte, Ilja M; Penninx, Brenda W; Corre, Tanguy; Masciullo, Corrado; Sala, Cinzia; Groop, Leif; Voight, Benjamin F; Melander, Olle; O’Donnell, Christopher J; Salomaa, Veikko; d’Adamo, Adamo Pio; Fabretto, Antonella; Faletra, Flavio; Ulivi, Sheila; Del Greco, M Fabiola; Facheris, Maurizio; Collins, Francis S; Bergman, Richard N; Beilby, John P; Hung, Joseph; Musk, A William; Mangino, Massimo; Shin, So-Youn; Soranzo, Nicole; Watkins, Hugh; Goel, Anuj; Hamsten, Anders; Gider, Pierre; Loitfelder, Marisa; Zeginigg, Marion; Hernandez, Dena; Najjar, Samer S; Navarro, Pau; Wild, Sarah H; Corsi, Anna Maria; Singleton, Andrew; de Geus, Eco JC; Willemsen, Gonneke; Parker, Alex N; Rose, Lynda M; Buckley, Brendan; Stott, David; Orru, Marco; Uda, Manuela; van der Klauw, Melanie M; Zhang, Weihua; Li, Xinzhong; Scott, James; Chen, Yii-Der Ida; Burke, Gregory L; Kähönen, Mika; Viikari, Jorma; Döring, Angela; Meitinger, Thomas; Davies, Gail; Starr, John M; Emilsson, Valur; Plump, Andrew; Lindeman, Jan H; ’t Hoen, Peter AC; König, Inke R; Felix, Janine F; Clarke, Robert; Hopewell, Jemma C; Ongen, Halit; Breteler, Monique; Debette, Stéphanie; DeStefano, Anita L; Fornage, Myriam; Mitchell, Gary F; Smith, Nicholas L; Holm, Hilma; Stefansson, Kari; Thorleifsson, Gudmar; Thorsteinsdottir, Unnur; Samani, Nilesh J; Preuss, Michael; Rudan, Igor; Hayward, Caroline; Deary, Ian J; Wichmann, H-Erich; Raitakari, Olli T; Palmas, Walter; Kooner, Jaspal S; Stolk, Ronald P; Jukema, J Wouter; Wright, Alan F; Boomsma, Dorret I; Bandinelli, Stefania; Gyllensten, Ulf B; Wilson, James F; Ferrucci, Luigi; Schmidt, Reinhold; Farrall, Martin; Spector, Tim D; Palmer, Lyle J; Tuomilehto, Jaakko; Pfeufer, Arne; Gasparini, Paolo; Siscovick, David; Altshuler, David; Loos, Ruth JF; Toniolo, Daniela; Snieder, Harold; Gieger, Christian; Meneton, Pierre; Wareham, Nicholas J; Oostra, Ben A; Metspalu, Andres; Launer, Lenore; Rettig, Rainer; Strachan, David P; Beckmann, Jacques S; Witteman, Jacqueline CM; Erdmann, Jeanette; van Dijk, Ko Willems; Boerwinkle, Eric; Boehnke, Michael; Ridker, Paul M; Jarvelin, Marjo-Riitta; Chakravarti, Aravinda; Abecasis, Goncalo R; Gudnason, Vilmundur; Newton-Cheh, Christopher; Levy, Daniel; Munroe, Patricia B; Psaty, Bruce M; Caulfield, Mark J; Rao, Dabeeru C

    2012-01-01

    Numerous genetic loci influence systolic blood pressure (SBP) and diastolic blood pressure (DBP) in Europeans 1-3. We now report genome-wide association studies of pulse pressure (PP) and mean arterial pressure (MAP). In discovery (N=74,064) and follow-up studies (N=48,607), we identified at genome-wide significance (P= 2.7×10-8 to P=2.3×10-13) four novel PP loci (at 4q12 near CHIC2/PDGFRAI, 7q22.3 near PIK3CG, 8q24.12 in NOV, 11q24.3 near ADAMTS-8), two novel MAP loci (3p21.31 in MAP4, 10q25.3 near ADRB1) and one locus associated with both traits (2q24.3 near FIGN) which has recently been associated with SBP in east Asians. For three of the novel PP signals, the estimated effect for SBP was opposite to that for DBP, in contrast to the majority of common SBP- and DBP-associated variants which show concordant effects on both traits. These findings indicate novel genetic mechanisms underlying blood pressure variation, including pathways that may differentially influence SBP and DBP. PMID:21909110

  10. Numerical studies of wall–plasma interactions and ionization phenomena in an ablative pulsed plasma thruster

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Lei [Beijing Research Institute of Precise Mechatronic Controls, Beijing 100076 (China); School of Astronautics, Beihang University, Beijing 100191 (China); Zeng, Guangshang; Huang, Yuping [Beijing Research Institute of Precise Mechatronic Controls, Beijing 100076 (China); Tang, Haibin [School of Astronautics, Beihang University, Beijing 100191 (China); Liu, Xiangyang [School of Aerospace Engineering, Beijing Institute of Technology, Beijing 100081 (China)

    2016-07-15

    Wall–plasma interactions excited by ablation controlled arcs are very critical physical processes in pulsed plasma thrusters (PPTs). Their effects on the ionization processes of ablated vapor into discharge plasma directly determine PPT performances. To reveal the physics governing the ionization phenomena in PPT discharge, a modified model taking into account the pyrolysis effect of heated polytetrafluoroethylene propellant on the wall–plasma interactions was developed. The feasibility of the modified model was analyzed by creating a one-dimensional simulation of a rectangular ablative PPT. The wall–plasma interaction results based on this modified model were found to be more realistic than for the unmodified model; this reflects the dynamic changes of the inflow parameters during discharge in our model. Furthermore, the temporal and spatial variations of the different plasma species in the discharge chamber were numerically studied. The numerical studies showed that polytetrafluoroethylene plasma was mainly composed of monovalent ions; carbon and fluorine ions were concentrated in the upstream and downstream discharge chamber, respectively. The results based on this modified model were in good agreement with the experimental formation times of the various plasma species. A large number of short-lived and highly ionized carbon and fluorine species (divalent and trivalent ions) were created during initial discharge. These highly ionized species reached their peak density earlier than the singly ionized species.

  11. Development of an ultrasonic pulse-echo (UPE) technique for aircraft icing studies

    Science.gov (United States)

    Liu, Yang; Chen, Wen-Li; Bond, Leonard J.; Hu, Hui

    2014-02-01

    Aircraft operating in some cold weather conditions face the risk of icing. Icing poses a threat to flight safety and its management is expensive. Removing light frost on a clear day from a medium-size business jet can cost 300, heavy wet snow removal can cost 3,000 and removal of accumulated frozen/freezing rain can cost close to 10,000. Understanding conditions that lead to severe icing events is important and challenging. When an aircraft or rotorcraft flies in a cold climate, some of the super cooled droplets impinging on exposed aircraft surfaces may flow along the surface prior to freezing and give various forms and shapes of ice. The runback behavior of a water film on an aircraft affects the morphology of ice accretion and the rate of formation. In this study, we report the recent progress to develop an Ultrasonic Pulse-Echo (UPE) technique to provide real-time thickness distribution measurements of surface water flows driven by boundary layer airflows for aircraft icing studies. A series of initial experimental investigations are conducted in an ice wind tunnel employing an array of ultrasonic transducers placed underneath the surface of a flat plate. The water runback behavior on the plate is evaluated by measuring the thickness profile variation of the water film along the surface by using the UPE technique under various wind speed and flow rate conditions.

  12. Development of an ultrasonic pulse-echo (UPE) technique for aircraft icing studies

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Yang; Hu, Hui [Department of Aerospace Engineering, Iowa State University, 2271 Howe Hall, Room 1200, Ames, IA 50011 (United States); Chen, Wen-Li [Department of Aerospace Engineering, Iowa State University, 2271 Howe Hall, Room 1200, Ames, IA 50011 (United States); School of Civil Engineering, Harbin Institute of Technology, Harbin, Heilongjiang 150090 (China); Bond, Leonard J. [Department of Aerospace Engineering, Iowa State University, 2271 Howe Hall, Room 1200, Ames, IA 50011 (United States); Center for Nondestructive Evaluation, Iowa State University, 1915 Scholl Road, 151 ASC II, Ames, IA 50011 (United States)

    2014-02-18

    Aircraft operating in some cold weather conditions face the risk of icing. Icing poses a threat to flight safety and its management is expensive. Removing light frost on a clear day from a medium-size business jet can cost $300, heavy wet snow removal can cost $3,000 and removal of accumulated frozen/freezing rain can cost close to $10,000. Understanding conditions that lead to severe icing events is important and challenging. When an aircraft or rotorcraft flies in a cold climate, some of the super cooled droplets impinging on exposed aircraft surfaces may flow along the surface prior to freezing and give various forms and shapes of ice. The runback behavior of a water film on an aircraft affects the morphology of ice accretion and the rate of formation. In this study, we report the recent progress to develop an Ultrasonic Pulse-Echo (UPE) technique to provide real-time thickness distribution measurements of surface water flows driven by boundary layer airflows for aircraft icing studies. A series of initial experimental investigations are conducted in an ice wind tunnel employing an array of ultrasonic transducers placed underneath the surface of a flat plate. The water runback behavior on the plate is evaluated by measuring the thickness profile variation of the water film along the surface by using the UPE technique under various wind speed and flow rate conditions.

  13. Human exposure from pulsed magnetic field therapy mats: a numerical case study with three commercial products.

    Science.gov (United States)

    De Santis, Valerio; Douglas, Mark; Nadakuduti, Jagadish; Benkler, Stefan; Chen, Xi Lin; Kuster, Niels

    2015-02-01

    A previous study found that incident magnetic field exposure from pulsed magnetic field therapy (PMFT) mats can exceed ICNIRP 1998 reference levels. Due to the popularity of PMFT mats for private therapeutic use, regulators need to know if the products are compliant with the basic restrictions and how overexposure can be determined. This case study's objective was to test if such products are intrinsically compliant with ICNIRP 1998 and ICNIRP 2010 basic restrictions by evaluating three different commercially-available PMFT products. In the first step, experimentally validated numerical models of these mats were developed. As a second step, the induced fields were evaluated in high-resolution anatomical models of the IT'IS Virtual Population for various lying positions and compared to the safety guidelines. As expected, a strong influence of exposure on the PMFT design, anatomy, lying position and body orientation was found. The maximum exposure of one PMFT exceeds 3.1 times the basic restrictions of ICNIRP 1998 for the central nervous system tissues and 1.36 times the limit of ICNIRP 2010 for the peripheral tissues. Body loops can significantly increase the electric fields close to the skin, e.g., when the hand and thigh are in contact during mat use. In conclusion, PMFT products are not intrinsically compliant with ICNIRP 1998 and ICNIRP 2010 basic restrictions and therefore require special considerations. © 2015 Wiley Periodicals, Inc.

  14. Pulse radiolysis studies of mangiferin: A C-glycosyl xanthone isolated from Mangifera indica

    Energy Technology Data Exchange (ETDEWEB)

    Mishra, B. [Radiation Chemistry and Chemical Dynamics Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400085 (India); Priyadarsini, K.Indira [Radiation Chemistry and Chemical Dynamics Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400085 (India)]. E-mail: kindira@apsara.barc.ernet.in; Sudheerkumar, M. [College of Pharmaceutical Sciences, Kasturba Medical College, Manipal 576119 (India); Unnikrishhnan, M.K. [College of Pharmaceutical Sciences, Kasturba Medical College, Manipal 576119 (India); Mohan, H. [Radiation Chemistry and Chemical Dynamics Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400085 (India)

    2006-01-15

    Pulse radiolysis technique has been employed to study the reaction of different oxidizing and reducing radicals with mangiferin. The reaction of {sup {center_dot}}OH radical showed the formation of transient species absorbing in 380-390 and 470-480 nm region. The reaction with specific one-electron oxidants (N{sub 3} {sup {center_dot}}, CCl{sub 3}O{sub 2} {sup {center_dot}}) also showed the formation of similar transient absorption bands and is assigned to phenoxyl radicals. The pK {sub a} values of the transient species have been determined to be 6.3 and 11.9. One-electron oxidation potential of mangiferin at pH 9 has been found to be 0.62 V vs. NHE. The reaction of e{sub aq} {sup -} showed the formation of transient species with {lambda} {sub max} at 340 nm, which is assigned to the ketyl anion radical formed on addition of e{sub aq} {sup -} at carbonyl site. Reactions of one-electron oxidised mangiferin radicals with ascorbic acid have also been studied.

  15. Pulse radiolysis studies of mangiferin: A C- glycosyl xanthone isolated from Mangifera indica

    Science.gov (United States)

    Mishra, B.; Priyadarsini, K. Indira; Sudheerkumar, M.; Unnikrishhnan, M. K.; Mohan, H.

    2006-01-01

    Pulse radiolysis technique has been employed to study the reaction of different oxidizing and reducing radicals with mangiferin. The reaction of rad OH radical showed the formation of transient species absorbing in 380-390 and 470-480 nm region. The reaction with specific one-electron oxidants (N 3rad , CCl 3O 2rad ) also showed the formation of similar transient absorption bands and is assigned to phenoxyl radicals. The p Ka values of the transient species have been determined to be 6.3 and 11.9. One-electron oxidation potential of mangiferin at pH 9 has been found to be 0.62 V vs. NHE. The reaction of e aq- showed the formation of transient species with λmax at 340 nm, which is assigned to the ketyl anion radical formed on addition of e aq- at carbonyl site. Reactions of one-electron oxidised mangiferin radicals with ascorbic acid have also been studied.

  16. Predictive study of the poloidal field coil insert behaviour under pulsed current tests

    Science.gov (United States)

    Lacroix, B.; Ciazynski, D.; Duchateau, J. L.; Nicollet, S.; Pauty, N.

    2008-02-01

    Within the ITER Poloidal Field conductor design validation, the Poloidal Field Conductor Insert (PFCI) has been manufactured and will be tested in the Central Solenoid Model Coil (CSMC) facility at JAEA Naka (Japan). In this test facility, the PFCI can be tested under ITER-relevant operating conditions, the field produced by the CSMC being varied to simulate the real situation of the PF coils in ITER. Predictive analyses have been performed in order to study the electromagnetic and thermal-hydraulic behaviour of the PFCI, under two scenarios proposed for pulsed current tests. During these scenarios, simulations have been performed with the THEA code, in which classical formulas for the AC losses in a cable have been introduced. The study focuses on the lower part of the winding, which is a 44 m long conductor including a joint. It covers the sample thermal-hydraulic behaviour with particular emphasis on the losses. Due to the overcompaction in the joint area, the total energy dissipated during a scenario can be equivalent in the joint and in the conductor, in spite of the reduced length of the joint (0.45 m). This particular point is discussed and has led to the analysis of the temperature margin in the joint.

  17. Pulsed lasers versus continuous light sources in capillary electrophoresis and fluorescence detection studies: Photodegradation pathways and models

    Energy Technology Data Exchange (ETDEWEB)

    Boutonnet, Audrey; Morin, Arnaud [Picometrics Technologies, 478 Rue de la Découverte, Labège France (France); Petit, Pierre [Institut de Mathématiques, Université de Toulouse, Université Paul Sabatier, Toulouse CEDEX 04 (France); Vicendo, Patricia; Poinsot, Véréna [Laboratoire des IMRCP, UMR 5623, Université de Toulouse, Université Paul Sabatier, Toulouse CEDEX 04 (France); Couderc, François, E-mail: couderc@chimie.ups-tlse.fr [Laboratoire des IMRCP, UMR 5623, Université de Toulouse, Université Paul Sabatier, Toulouse CEDEX 04 (France)

    2016-03-17

    Pulsed lasers are widely used in capillary electrophoresis (CE) studies to provide laser induced fluorescence (LIF) detection. Unfortunately pulsed lasers do not give linear calibration curves over a wide range of concentrations. While this does not prevent their use in CE/LIF studies, the non-linear behavior must be understood. Using 7-hydroxycoumarin (7-HC) (10–5000 nM), Tamra (10–5000 nM) and tryptophan (1–200 μM) as dyes, we observe that continuous lasers and LEDs result in linear calibration curves, while pulsed lasers give polynomial ones. The effect is seen with both visible light (530 nm) and with UV light (355 nm, 266 nm). In this work we point out the formation of byproducts induced by pulsed laser upon irradiation of 7-HC. Their separation by CE using two Zeta LIF detectors clearly shows that this process is related to the first laser detection. All of these photodegradation products can be identified by an ESI-/MS investigation and correspond to at least two 7HC dimers. By using the photodegradation model proposed by Heywood and Farnsworth (2010) and by taking into account the 7-HC results and the fact that in our system we do not have a constant concentration of fluorophore, it is possible to propose a new photochemical model of fluorescence in LIF detection. The model, like the experiment, shows that it is difficult to obtain linear quantitation curves with pulsed lasers while UV-LEDs used in continuous mode have this advantage. They are a good alternative to UV pulsed lasers. An application involving the separation and linear quantification of oligosaccharides labeled with 2-aminobezoic acid is presented using HILIC and LED (365 nm) induced fluorescence. - Highlights: • No linear calibration curves are obtained in CE/Pulsed-LIF detection. • Photodegradation and photodimerisation are responsible of this non linearity. • A mathematical model of this phenomenon is presented. • 7 hydroxycoumarin in CE/LIF is used to verify the

  18. Gamma-ray bursts observed by the INTEGRAL-SPI anticoincidence shield: A study of individual pulses and temporal variability

    DEFF Research Database (Denmark)

    Ryde, F.; Borgonovo, L.; Larsson, S.

    2003-01-01

    self-similar in shape. There is also a weak tendency for the pulses with steep power-law decays to be more asymmetric. Third, the variability of the complex light-curves is studied by analyzing their power-density-spectra (PDS) and their RMS variability. The averaged PDS, of the whole sample......We study a set of 28 GRB light-curves detected between 15 December 2002 and 9 June 2003 by the anti-coincidence shield of the spectrometer (SPI) of INTEGRAL. During this period it has detected 50 bursts, that have been confirmed by other instruments, with a time resolution of 50 ms. First, we...... derive the basic characteristics of the bursts: various duration measures, the count peak flux and the count fluence. Second, a sub-sample of 11 bursts with 12 individual, well-separated pulses is studied. We fit the pulse shape with a model by Kocevski et al. (2003) and find that the pulses are quite...

  19. A Study of Tongue and Pulse Diagnosis in Traditional Korean Medicine for Stroke Patients Based on Quantification Theory Type II

    Directory of Open Access Journals (Sweden)

    Mi Mi Ko

    2013-01-01

    Full Text Available In traditional Korean medicine (TKM, pattern identification (PI diagnosis is important for treating diseases. The aim of this study was to comprehensively investigate the relationship between the PI type and tongue diagnosis or pulse diagnosis variables. The study included 1,879 stroke patients who were admitted to 12 oriental medical university hospitals from June 2006 through March 2009. The status of the pulse and tongue was examined in each patient. Additionally, to investigate relatively important indicators related to specialist PI, the quantification theory type II analysis was performed regarding the PI type. In the first axis quantification of the external criteria, the Qi-deficiency and the Yin-deficiency patterns were located in the negative direction, while the dampness-phlegm (DP and fire-heat patterns were located in the positive direction. The explanatory variable with the greatest impact on the assessment was a fine pulse. In the second axis quantification, the external criteria were divided into either the DP or non-DP patterns. The slippery pulse exhibited the greatest effect on the division. This study attempted to build a model using a statistical method to objectively quantify PI and various indicators that constitute the unique diagnosis system of TKM. These results should assist the development of future diagnostic standards in stroke PI.

  20. PERIPHERAL APPLICATION OF REPETITIVE PULSE MAGNETIC STIMULATION ON JOINT CONTRACTURE FOR MOBILITY RESTORATION: CONTROLLED RANDOMIZED STUDY

    Directory of Open Access Journals (Sweden)

    Efthimios J. Kouloulas

    2016-10-01

    Full Text Available Background: Joint contracture is a limitation in the passive or active range of motion (ROM of a joint, where in addition to the mobility limiting factor the pain is also present. Repetitive pulsed Magnetic Stimulation (rPMS appears to be an effective, non-invasive and safety solution for treating this condition. Therefore aim of this study was to evaluate the effect of rPMS in treating joint contracture. Methods: 30 subjects with joint contracture in the knee were enrolled in this study and divided respectively into Treatment and Control group. The treatment group were delivered with rPMS therapy. The control group was delivered with conventional physiotherapy method (ultrasound. The primary outcome measurements were: 1. Mobility evaluation by goniometry (ROM in degrees while performing flexion and Patient Functional Assessment Questionnaire (PFAQ for ability to perform Activities of Daily Living (ADL and 2. Pain evaluation by 10-point Visual Analog Scale (VAS for pain perception. Absence of adverse events was set as a secondary measure. Results: The results of the study show statistical difference (p<0.05 between the levels of improvement of all studied parameters while comparing between both groups. The results suggest greater immobility restoration and pain relieving effect of the rPMS in comparison to conventional physiotherapy method. Conclusion: rPMS an effective and safe non-invasive method for mobility restoration and pain relief in case of joint contractures. This study suggests the method as beneficial and quality of life ameliorating among patients suffering from immobilized joints accompanied by pain.

  1. Hertzian impact: experimental study of the force pulse and resulting stress waves.

    Science.gov (United States)

    McLaskey, Gregory C; Glaser, Steven D

    2010-09-01

    Ball impact has long been used as a repeatable source of stress waves in solids. The amplitude and frequency content of the waves are a function of the force-time history, or force pulse, that the ball imposes on the massive body. In this study, Glaser-type conical piezoelectric sensors are used to measure vibrations induced by a ball colliding with a massive plate. These measurements are compared with theoretical estimates derived from a marriage of Hertz theory and elastic wave propagation. The match between experiment and theory is so close that it not only facilitates the absolute calibration the sensors but it also allows the limits of Hertz theory to be probed. Glass, ruby and hardened steel balls 0.4 to 2.5 mm in diameter were dropped onto steel, glass, aluminum, and polymethylmethacrylate plates at a wide range of approach velocities, delivering frequencies up to 1.5 MHz into these materials. Effects of surface properties and yielding of the plate material were analyzed via the resulting stress waves and simultaneous measurements of the ball's coefficient of restitution. The sensors are sensitive to surface normal displacements down to about +/-1 pm in the frequency range of 20 kHz to over 1 MHz.

  2. Predicted effects of pulse width programming in spinal cord stimulation: a mathematical modeling study.

    Science.gov (United States)

    Lee, Dongchul; Hershey, Brad; Bradley, Kerry; Yearwood, Thomas

    2011-07-01

    To understand the theoretical effects of pulse width (PW) programming in spinal cord stimulation (SCS), we implemented a mathematical model of electrical fields and neural activation in SCS to gain insight into the effects of PW programming. The computational model was composed of a finite element model for structure and electrical properties, coupled with a nonlinear double-cable axon model to predict nerve excitation for different myelinated fiber sizes. Mathematical modeling suggested that mediolateral lead position may affect chronaxie and rheobase values, as well as predict greater activation of medial dorsal column fibers with increased PW. These modeling results were validated by a companion clinical study. Thus, variable PW programming in SCS appears to have theoretical value, demonstrated by the ability to increase and even 'steer' spatial selectivity of dorsal column fiber recruitment. It is concluded that the computational SCS model is a valuable tool to understand basic mechanisms of nerve fiber excitation modulated by stimulation parameters such as PW and electric fields.

  3. Thermal decomposition of propargyl alcohol: single pulse shock tube experimental and ab initio theoretical study.

    Science.gov (United States)

    Sharath, N; Reddy, K P J; Arunan, E

    2014-08-07

    Thermal decomposition of propargyl alcohol (C3H3OH), a molecule of interest in interstellar chemistry and combustion, was investigated using a single pulse shock tube in the temperature ranging from 953 to 1262 K. The products identified include acetylene, propyne, vinylacetylene, propynal, propenal, and benzene. The experimentally observed overall rate constant for thermal decomposition of propargyl alcohol was found to be k = 10((10.17 ± 0.36)) exp(-(39.70 ± 1.83)/RT) s(-1). Ab initio theoretical calculations were carried out to understand the potential energy surfaces involved in the primary and secondary steps of propargyl alcohol thermal decomposition. Transition state theory was used to predict the rate constants, which were then used and refined in a kinetic simulation of the product profile. The first step in the decomposition is C-O bond dissociation, leading to the formation of two important radicals in combustion, OH and propargyl. This has been used to study the reverse OH + propargyl radical reaction, about which there appears to be no prior work. Depending on the site of attack, this reaction leads to propargyl alcohol or propenal, one of the major products at temperatures below 1200 K. A detailed mechanism has been derived to explain all the observed products.

  4. Pulse radiolysis study of the reactions of catechins with nitrogen dioxide

    Science.gov (United States)

    Gebicki, Jerzy L.; Meisner, Piotr; Stawowska, Katarzyna; Gebicka, Lidia

    2012-12-01

    Nitrogen dioxide (•NO2), one of the oxidizing radicals formed in vivo is suspected to play a role in various pathophysiological processes. The reactions of •NO2 with dietary catechins, the group of flavonoids present in high amounts in green tea and red wine, have been investigated by pulse radiolysis method. The kinetics of the reaction of •NO2 with gallic acid have been also studied for comparison. The spectra of transient intermediates are presented. The rate constants of the reaction of •NO2 with catechin, epigallocatechin, epigallocatechin gallate and gallic acid determined by the competition method with 2,2'-azinobis-(3-ethylbenzthiazoline-6-sulfonate) at pH 7.0 and room temperature have been found to be 0.9, 1.0, 2.3 and 0.5×108 M-1 s-1, respectively. The values for catechins are among the highest reported for the reactions of •NO2 with non-radical compounds.

  5. Spectroscopic study of 50 Hz pulsed Ar-O2 mixture plasma

    Science.gov (United States)

    Imran, M.; Rehman, N. U.; Khan, A. W.; Zaka-ul-Islam, M.; Shafiq, M.; Zakaullah, M.

    2016-06-01

    Plasma sterilization is widely used to disinfect the heat sensitive materials. In this study, we have investigated 50 Hz pulsed capacitively coupled plasma (CCP) system operated in Ar-O2 mixture. Optical emission spectroscopy (OES) is used to identify the optimum conditions suitable for plasma based sterilization. Explicitly, excitation temperature of Ar-I lines, atomic oxygen density, dissociation fraction and UV radiation intensity are measured as a function of discharge parameters. The excitation temperature is calculated using Boltzmann plot method whereas OES has also been employed to evaluate the ground state atomic oxygen density and dissociation fraction. Similarly the normalized UV radiation intensity is determined from UV spectrum in 200-400 nm range. The results show that the total UV emission has optimum value at 20% oxygen, 2 mbar pressure and 2.68 mA/cm2 current density in the mixture. While excitation temperature, atomic oxygen density and dissociation fraction increase with the current density. A comparison with the literature suggests 50 Hz CCP system operated in Ar-O2 mixture has the potential of a cheap and reliable system for plasma sterilization.

  6. Comparative Studies on Preparation of Large Plant DNA Fragments by Pulse Field Gel Electrophoresis

    Institute of Scientific and Technical Information of China (English)

    Yang Jiliang(杨继良); Wang Qinghua(王庆华); Deng Daiyong; Yang Dianer; Jin Demin; Weng Manli; Zhang Juren; Wang Bin

    2004-01-01

    The preparation of large plant DNA fragments is extremely important to the construction of large insert DNA libraries (YAC, BAC, PAC and TAC). Although several techniques have been developed in each step of large plant DNA fragments preparation, the whole processing remains complicated and difficult. Based on authors research experience and the recent worldwide development in this field, the following aspects are discussed in this paper: techniques of plant high molecular weight (HMW) DNA purification by pre-electrophoresis, the optimal conditions for the partial digestion of the HMW DNA by HindIII, the isolation effects of of large plant DNA fragments (100~400 kb) with different parameters of pulse field gel electrophoresis (PFGE), and the recovery of large DNA fragments. Through comparative studies, the advantages and disadvantages of each technique are discussed and some recommendations are proposed for preparing high quality large plant DNA fragments. The suggested techniques have been used in preparing the large DNA fragments of maize, rice, moss, laver, sea tangle and peach,and similar results are obtained among all the materials. This paper only reports the results using maize as material.

  7. Applications of pulsed EPR spectroscopy to structural studies of sulfite oxidizing enzymes

    Energy Technology Data Exchange (ETDEWEB)

    Klein, Eric L.; Astashkin, Andrei V.; Raitsimring, Arnold M.; Enemark, John H.

    2013-01-01

    Sulfite oxidizing enzymes (SOEs), including sulfite oxidase (SO) and bacterial sulfite dehydrogenase (SDH), catalyze the oxidation of sulfite (SO32-) to sulfate (SO42-). The active sites of SO and SDH are nearly identical, each having a 5-coordinate, pseudo-square-pyramidal Mo with an axial oxo ligand and three equatorial sulfur donor atoms. One sulfur is from a conserved Cys residue and two are from a pyranopterindithiolene (molybdopterin, MPT) cofactor. The identity of the remaining equatorial ligand, which is solvent-exposed, varies during the catalytic cycle. Numerous in vitro studies, particularly those involving electron paramagnetic resonance (EPR) spectroscopy of the Mo(V) states of SOEs, have shown that the identity and orientation of this exchangeable equatorial ligand depends on the buffer pH, the presence and concentration of certain anions in the buffer, as well as specific point mutations in the protein. Until very recently, however, EPR has not been a practical technique for directly probing specific structures in which the solvent-exposed, exchangeable ligand is an O, OH-, H2O, SO32-, or SO42- group, because the primary O and S isotopes (16O and 32S) are magnetically silent (I = 0). This review focuses on the recent advances in the use of isotopic labeling, variable-frequency high resolution pulsed EPR spectroscopy, synthetic model compounds, and DFT calculations to elucidate the roles of various anions, point mutations, and steric factors in the formation, stabilization, and transformation of SOE active site structures.

  8. Pulse-induced nonequilibrium dynamics of acetylene inside carbon nanotube studied by an ab initio approach.

    Science.gov (United States)

    Miyamoto, Yoshiyuki; Zhang, Hong; Rubio, Angel

    2012-06-05

    Nanoscale molecular confinement substantially modifies the functionality and electronic properties of encapsulated molecules. Many works have approached this problem from the perspective of quantifying ground-state molecular changes, but little is known about the nonequilibrium dynamics of encapsulated molecular system. In this letter, we report an analysis of the nonequilibrium dynamics of acetylene (C(2)H(2)) inside a semiconducting carbon nanotube (CNT). An ultrashort high-intense laser pulse (2 fs width and 10(15) W/cm(2) intensity) brings the systems out of equilibrium. This process is modeled by comprehensive first-principles time-dependent density-functional simulations. When encapsulated, acetylene dimer, unlike a single acetylene molecule, exhibits correlated vibrational dynamics (C-C bond rotation and H-C-C bending) that is markedly different from the dynamics observed in the gas phase. This result highlights the role of CNT in modulating the optical electric field within the tube. At longer simulation timescales (> 20 fs) in the largest-diameter tube studied here [CNT(14,0)], we observe synchronized rotation about the C-C axes in the dimer and ultimately ejection of one of the four hydrogen atoms. Our results illustrate the richness of photochemical phenomena in confined geometries.

  9. Perfluorobutyric Acid and its Monohydrate: a Chirped Pulse and Cavity Based Fourier Transform Microwave Spectroscopic Study

    Science.gov (United States)

    Thomas, Javix; Serrato, Agapito, III; Lin, Wei; Jaeger, Wolfgang; Xu, Yunjie

    2014-06-01

    Perfluorobutyric acid (PFBA) is highly soluble in water and is a molecule of environmental importance. Rotational spectra of PFBA and its monohydrate were studied using a broadband chirped pulse and a narrow band cavity based Fourier transform microwave spectrometers and high level ab initio calculations. Extensive conformational search was performed for both the acid and its monohydrate at the MP2/6-311++G(2d,p) level of theory. Two and three conformers were predicted for PFBA and its monohydrate, respectively. One set of rotational transitions of PFBA and its mono-hydrate in each case was observed and assigned. Based on the broadband spectra obtained, one can confidently conclude that only one dominate conformer exists in each case. The orientation of the hydroxyl group in PFBA was determined using isotopic analysis. Comparison of the observed transition intensities and the calculated electric dipole moment components allowed one to identify the most stable monohydrate conformation which takes on the insertion hydrogen-bonding topology. Comparison to the shorter chain analogues, i.e. trifluoroacetic acid, perfluoropropionic acid, and their monohydrates, was made to elucidate the general trend in their conformational preference and binding topologies.

  10. Perfluorobutyric acid and its monohydrate: a chirped pulse and cavity based fourier transform microwave spectroscopic study.

    Science.gov (United States)

    Thomas, Javix; Serrato, Agapito; Lin, Wei; Jäger, Wolfgang; Xu, Yunjie

    2014-05-12

    Rotational spectra of perfluorobutyric acid (PFBA) and its monohydrate were studied with a broadband chirped pulse and a narrow-band cavity based Fourier transform microwave spectrometer, and high-level ab initio calculations. Extensive conformational searches were performed for both the acid and its monohydrate at the MP2/6-311++G(2d,p) level of theory. Two and three conformers were predicted to exist for PFBA and its monohydrate, respectively. One set of rotational transitions was observed and assigned for each, PFBA and its monohydrate. Based on the measured broadband spectra, we confidently conclude that only one dominant conformer exists in each case. The orientation of the hydroxyl group in PFBA was determined by using isotopic analysis. Comparison of the observed transition intensities and the calculated electric dipole moment components allowed us to identify the most stable monohydrate conformation, which takes on an insertion hydrogen-bonding topology. Comparisons to the shorter chain analogues, that is, trifluoroacetic acid, perfluoropropionic acid, and their monohydrates, are made to elucidate the general trend in their conformational preference and binding topologies.

  11. Experimental study on the development of a micro-drilling cycle using ultrashort laser pulses

    Science.gov (United States)

    Romoli, L.; Vallini, R.

    2016-03-01

    Microholes for the production of high precision devices were obtained by ultrashort pulsed laser machining of martensitic stainless steels. A micro-drilling cycle based on the sequence of a drilling through phase, an enlargement and finishing phase is proposed in order to solve the trade-off between process time and quality of the ablated surfaces without making use of complex design of experiments. The three phases were studied taking into account the evolution of the microhole shape as a function of the main process parameters (number of passes per phase, incidence angle and radius of the beam trajectory respect to the hole's axis). Experiments testified that the drilling strategy was able to produce cylindrical holes with diameter of 180±2 μm on a 350 μm thick plate in total absence of burrs and debris within a drilling time of 3.75 s. Repeatability tests showed a process capability of nearly 99%. SEM inspection of the inner surface of the microholes showed the presence of elongated and periodic ripples whose size and inclination can be controlled adjusting the incidence angle of the beam over the tapered surface before the ultimate finishing phase.

  12. Development and testing of a pulsed helium ion source for probing materials and warm dense matter studies

    Energy Technology Data Exchange (ETDEWEB)

    Ji, Q., E-mail: qji@lbl.gov; Seidl, P. A.; Waldron, W. L.; Takakuwa, J. H.; Persaud, A.; Schenkel, T. [Lawrence Berkeley National Laboratory, Berkeley, California 94720 (United States); Friedman, A.; Grote, D. P.; Barnard, J. J. [Lawrence Berkeley National Laboratory, Berkeley, California 94720 (United States); Lawrence Livermore National Laboratory, Livermore, California 94550 (United States)

    2016-02-15

    The neutralized drift compression experiment was designed and commissioned as a pulsed, linear induction accelerator to drive thin targets to warm dense matter (WDM) states with peak temperatures of ∼1 eV using intense, short pulses (∼1 ns) of 1.2 MeV lithium ions. At that kinetic energy, heating a thin target foil near the Bragg peak energy using He{sup +} ions leads to more uniform energy deposition of the target material than Li{sup +} ions. Experiments show that a higher current density of helium ions can be delivered from a plasma source compared to Li{sup +} ions from a hot plate type ion source. He{sup +} beam pulses as high as 200 mA at the peak and 4 μs long were measured from a multi-aperture 7-cm-diameter emission area. Within ±5% variation, the uniform beam area is approximately 6 cm across. The accelerated and compressed pulsed ion beams can be used for materials studies and isochoric heating of target materials for high energy density physics experiments and WDM studies.

  13. Analysis of internal crack propagation in silicon due to permeable pulse laser irradiation: study on processing mechanism of stealth dicing

    Science.gov (United States)

    Ohmura, Etsuji; Kawahito, Yuta; Fukumitsu, Kenshi; Okuma, Junji; Morita, Hideki

    2011-02-01

    Stealth dicing (SD) is an innovative dicing method developed by Hamamatsu Photonics K.K. In the SD method, a permeable nanosecond laser is focused inside a silicon wafer and scanned horizontally. A thermal shock wave propagates every pulse toward the side to which the laser is irradiated, then a high dislocation density layer is formed inside the wafer after the thermal shock wave propagation. In our previous study, it was concluded that an internal crack whose initiation is a dislocation is propagated when the thermal shock wave by the next pulse overlaps with this layer partially. In the experimental result, the trace that a crack is progressed gradually step by step was observed. In this study, the possibility of internal crack propagation by laser pulses was investigated. A two-dimensional thermal stress analysis based on the linear fracture mechanics was conducted using the stress distribution obtained by the axisymmetric thermal stress analysis. As a result, the validity of the hypothesis based on a heat transfer analysis result previously presented was supported. Also it was concluded that the internal crack is propagated by at least two pulses.

  14. Optimization of the ionization time of an atom with tailored laser pulses: a theoretical study

    CERN Document Server

    Kammerlander, David; Marques, Miguel A L

    2016-01-01

    How fast can a laser pulse ionize an atom? We address this question by considering pulses that carry a fixed time-integrated energy per-area, and finding those that achieve the double requirement of maximizing the ionization that they induce, while having the shortest duration. We formulate this double-objective quantum optimal control problem by making use of the Pareto approach to multi-objetive optimization, and the differential evolution genetic algorithm. The goal is to find out how much a precise time-profiling of ultra-fast, large-bandwidth pulses may speed up the ionization process with respect to simple-shape pulses. We work on a simple one-dimensional model of hydrogen-like atoms (the P\\"oschl-Teller potential), that allows to tune the number of bound states that play a role in the ionization dynamics. We show how the detailed shape of the pulse accelerates the ionization process, and how the presence or absence of bound states influences the velocity of the process.

  15. Study of ultra-high gradient wakefield excitation by intense ultrashort laser pulses in plasma

    CERN Document Server

    Kotaki, H

    2002-01-01

    We investigate a mechanism of nonlinear phenomena in laser-plasma interaction, a laser wakefield excited by intense laser pulses, and the possibility of generating an intense bright electron source by an intense laser pulse. We need to understand and further employ some of these phenomena for our purposes. We measure self-focusing, filamentation, and the anomalous blueshift of the laser pulse. The ionization of gas with the self-focusing causes a broad continuous spectrum with blueshift. The normal blueshift depends on the laser intensity and the plasma density. We, however, have found different phenomenon. The laser spectrum shifts to fixed wavelength independent of the laser power and gas pressure above some critical power. We call the phenomenon 'anomalous blueshift'. The results are explained by the formation of filaments. An intense laser pulse can excite a laser wakefield in plasma. The coherent wakefield excited by 2 TW, 50 fs laser pulses in a gas-jet plasma around 10 sup 1 sup 8 cm sup - sup 3 is mea...

  16. Enhancing caries resistance with a short-pulsed CO2 9.3-μm laser: a laboratory study (Conference Presentation)

    Science.gov (United States)

    Rechmann, Peter; Rechmann, Beate M.; Groves, William H.; Le, Charles; Rapozo-Hilo, Marcia L.; Featherstone, John D. B.

    2016-02-01

    The objective of this laboratory study was to test whether irradiation with a new 9.3µm microsecond short-pulsed CO2-laser enhances enamel caries resistance with and without additional fluoride applications. 101 human enamel samples were divided into 7 groups. Each group was treated with different laser parameters (Carbon-dioxide laser, wavelength 9.3µm, 43Hz pulse-repetition rate, pulse duration between 3μs to 7μs (1.5mJ/pulse to 2.9mJ/pulse). Using a pH-cycling model and cross-sectional microhardness testing determined the mean relative mineral loss delta Z (∆Z) for each group. The pH-cycling was performed with or without additional fluoride. The CO2 9.3μm short-pulsed laser energy rendered enamel caries resistant with and without additional fluoride use.

  17. A Pulsed Electric Field (PEF) bench static system to study bacteria inactivation

    Energy Technology Data Exchange (ETDEWEB)

    Cortese, Pietro; Dellacasa, Giuseppe; Gemme, Roberto [Department of Science and Advanced Technology, Eastern Piedmont University, Viale Teresa Michel 11, 15121-Alessandria (Italy); Bonetta, Sara; Bonetta, Silvia; Carraro, Elisabetta; Motta, Francesca [Department of Environmental and Life Science, Eastern Piedmont University, Viale Teresa Michel 11, 15121-Alessandria (Italy); Paganoni, Marco; Pizzichemi, Marco [Physics Department G. Occhialini, University of Milano-Bicocca, Piazza della Scienza 3, 20126-Milano (Italy)

    2011-06-15

    Pulsed Electric Fields (PEF) technology is a promising non-thermal processing method for inactivation of microorganisms. A small PEF bench system able to treat a 0.4 ml static liquid volume has been built and tested at the laboratories of the Universita del Piemonte Orientale in Alessandria, Italy. The technique used to produce the required fields consists of charging high voltage cables of various lengths and subsequently discharge them on a cylindrical cell. The pulse intensity can be adjusted to reach a maximum electric field in the cell of about 35 kV/cm and the pulse frequency can reach 10 Hz. We describe the PEF system in some detail and, as a benchmark of its performances, we report preliminary results obtained on Escherichia coli (ATCC 25922) at 10{sup 9} Cfu/ml concentration suspended in a McIlvaine buffer (pH 7.2).

  18. Study on a cascade pulse tube cooler with energy recovery: new method for approaching Carnot

    Science.gov (United States)

    Wang, L. Y.; Wu, M.; Zhu, J. K.; Jin, Z. Y.; Sun, X.; Gan, Z. H.

    2015-12-01

    A pulse tube cryocooler (PTC) can not achieve Carnot efficiency because the expansion work must be dissipated at the warm end of the pulse tube. How to recover this amount of dissipated work is a key for improving the PTC efficiency. A cascade PTC consists of PTCs those are staged by transmission tubes in between, these can be a two-stage or even more stages, each stage is driven by the recovered work from the last stage by a well-designed long transmission tube. It is shown that the more stages it has, the closer the efficiency will approach the Carnot efficiency. A two-stage cascade pulse tube cooler consisted of a primary and a secondary stage working at 233 K is designed, fabricated and tested in our lab. Experimental results show that the efficiency is improved by 33% compared with the single stage PTC.

  19. An Experimental Study of Ultrashort Pulsed Ytterbium-Doped Fibre Laser and Amplifier

    Institute of Scientific and Technical Information of China (English)

    YANG Ling-Zhen; XIONG Hong-Jun; CHEN Guo-Fu; WANG Yi-Shan; ZHAO Wei; CHENG Zhao

    2004-01-01

    @@ We report the generation of ultrashort pulses in ytterbium-doped fibre oscillator emitting around 1.05μm at a repetition rate of 17.6MHz. A diode laser with single silica fibre at 976nm pumps the ytterbium fibre laser, the aH-fibre picosecond pulsed oscillator has excellent stability and compact size, and freedom from misalignment. After amplifying, pulse energy of 3.4 nj and an average power of 60 mW are obtained. The compression is obtained with a grating pair out of the cavity. The compressor produces 307fs with the peak power 5.47kW. A practical fibre-based source with good performance is thus demonstrated.

  20. A study of ultrafast electron diffusion kinetics in ultrashort-pulse laser ablation of metals

    Institute of Scientific and Technical Information of China (English)

    Yang Jian-Jun; Liu Wei-Wei; Zhu Xiao-Nong

    2007-01-01

    Temperature dependence of the electron diffusion in metallic targets, where the electron-electron collision is the dominant process, is investigated with the help of an extended two-temperature model. In sharp contrast to the low electron temperature case, where only the electron-phonon collisions are commonly considered, the electron diffusion process underlying the high electron temperatures evolves dramatically different in both temporal and spatial domains.Calculated results of the ablation yield at different pulse durations are presented for a copper plate impinged by ultrashort laser pulses with energy fluences ranging from 0.1 J/cm2 to 10 J/cm2. The excellent agreement between the simulation results and the experimental data indicates the significant role of electron-electron collisions in material ablations using intense ultrashort laser pulses.

  1. Study of ultra-high gradient wakefield excitation by intense ultrashort laser pulses in plasma

    Science.gov (United States)

    Kotaki, Hideyuki; Kando, Masaki; Oketa, Takatsugu; Masuda, Shinichi; Koga, James K.; Kondo, Shuji; Kanazawa, Shuhei; Yokoyama, Takashi; Matoba, Toru; Nakajima, Kazuhisa

    2002-10-01

    We investigate a laser wakefield excited by intense laser pulses, and the possibility of generating an intense bright electron source by an intense laser pulse. The coherent wakefield excited by 2 TW, 50 fs laser pulses in a gas-jet plasma around 1018 cm-3 is measured with a time-resolved frequency domain interferometer (FDI). The results show an accelerating wakefield excitation of 20 GeV/m with good coherency. This is the first time-resolved measurement of laser wakefield excitation in a gas-jet plasma. The experimental results agree with the simulation results and linear theory. The pump-probe interferometer system of FDI will be modified to the optical injection system as a relativistic electron beam injector. In 1D particle in cell simulation we obtain results of high quality intense electron beam generation.

  2. Feasibility study on a short-pulsed IR wavelength for effective calculus fragmentation

    Science.gov (United States)

    Kang, Hyun Wook

    2015-05-01

    Laser-induced lithotripsy has been used for a minimally-invasive surgery to treat kidney-stone disease associated with urinary obstruction. A short-pulsed Tm:YAG laser (λ = 2.01 µm) was developed to improve fragmentation efficiency and was evaluated with a Ho:YAG laser (λ = 2.12 μm) as to its ablation feature and mass removal rate. Application of a train of sub-microsecond pulses with a lower energy at a frequency of 500 Hz created multiple events of cavitation that accompanied strong acoustic transients. During Tm:YAG irradiation, both high light absorption and secondary photomechanical impacts readily fragmented the calculus into small pieces (< 3 mm) and removed them 130 times faster than photothermal Ho:YAG lithotripsy. The proposed short-pulsed Tm:YAG approach may be an effective lithotripter for treating calculus disease.

  3. Radiation-induced pink nickel oligomeric clusters in water. Pulse radiolysis study.

    Science.gov (United States)

    Hioul, Mohamed Larbi; Lin, Mingzhang; Belloni, Jacqueline; Keghouche, Nassira; Marignier, Jean-Louis

    2014-10-09

    γ-rays and pulse radiolysis of aqueous solutions of Ni(2+) ions in the presence of polyacrylate (PA(-)) and 2-propanol leads to the formation of metastable species absorbing at 540 nm that are ascribed to "pink" oligomeric clusters of a few nickel atoms only. The molar absorption coefficient is evaluated as ε540 nm = 3300 ± 300 L mol(-1) cm(-1) per Ni(0) atom. The successive steps from the reduction of Ni(2+) into Ni(+) ions to the formation of the pink clusters at 540 nm under conditions of complexation by PA(-) are investigated by pulse radiolysis. The yield of the formation of pink clusters increases markedly with the irradiation dose rate, demonstrating the occurrence of the disproportionation of the [Ni(+), PA(-)] complex after a single electron pulse. The reduction and nucleation mechanisms, including rate constants, in competition with the back oxidation by protons, particularly at low dose rate, are discussed.

  4. Pump-probe studies of radiation induced defects and formation of warm dense matter with pulsed ion beams

    Science.gov (United States)

    Schenkel, T.; Persaud, A.; Gua, H.; Seidl, P. A.; Waldron, W. L.; Gilson, E. P.; Kaganovich, I. D.; Davidson, R. C.; Friedman, A.; Barnard, J. J.; Minior, A. M.

    2014-10-01

    We report results from the 2nd generation Neutralized Drift Compression Experiment at Berkeley Lab. NDCX-II is a pulsed, linear induction accelerator designed to drive thin foils to warm dense matter (WDM) states with peak temperatures of ~ 1 eV using intense, short pulses of 1.2 MeV lithium ions. Tunability of the ion beam enables pump-probe studies of radiation effects in solids as a function of excitation density, from isolated collision cascades to the onset of phase-transitions and WDM. Ion channeling is an in situ diagnostic of damage evolution during ion pulses with a sensitivity of channeled ions tracks lattice disorder evolution with a resolution of ~ 1 ns using fast current measurements. We will discuss pump-probe experiments with pulsed ion beams and the development of diagnostics for WDM and multi-scale (ms to fs) access to the materials physics of collision cascades e.g. in fusion reactor materials. Work performed under auspices of the US DOE under Contract No. DE-AC02-05CH11231.

  5. Nanosecond pulsed electric fields as a novel drug free therapy for breast cancer: an in vivo study.

    Science.gov (United States)

    Wu, Shan; Wang, Yu; Guo, Jinsong; Chen, Qunzhi; Zhang, Jue; Fang, Jing

    2014-02-28

    Nanosecond pulsed electric fields (nsPEFs) is a novel non-thermal approach to induce cell apoptosis. NsPEFs has been proven effective in treating several murine tumors, but few studies focus on its efficacy in treating human tumors. To determine if nsPEFs is equally effective in treatment of human breast cancer, 30 human breast cancer tumors across 30Balb/c (nu/nu) mice were exposed to 720 pulses of 100ns duration, at 4pulsespersecond and 30kV/cm. Two weeks after treatment, the growth of treated tumors was inhibited by 79%. Morphological changes of tumors were observed via a 3.0T clinical magnetic resonance imaging (MRI) system with a self-made surface coil. Pulsed tumors exhibited apoptosis evaluated by TUNEL staining, inhibition in Bcl-2 expression and decreased blood vessel density. Notably, CD34, vascular endothelial growth factor (VEGF) and VEGF receptor (VEGFR) expression in treated tumors were strongly suppressed. To evaluate the might-be adverse effects of nsPEFs in healthy tissues, normal skin was treated exactly the same way as tumors, and pulsed skin showed no permanent damages. The results suggest nsPEFs is able to inhibit human breast cancer development and suppress tumor blood vessel growth, indicating nsPEFs may serve as a novel therapy for breast cancer in the future.

  6. Optical time of flight studies of lithium plasma in double pulse laser ablation: Evidence of inverse Bremsstrahlung absorption

    Energy Technology Data Exchange (ETDEWEB)

    Sivakumaran, V.; Joshi, H. C.; Singh, R. K.; Kumar, Ajai, E-mail: ajai@ipr.res.in [Institute for Plasma Research, Bhat, Gandhinagar, Gujarat 382428 (India)

    2014-06-15

    The early stage of formation of lithium plasma in a collinear—double pulse laser ablation mode has been studied using optical time of flight (OTOF) spectroscopy as a function of inter-pulse delay time, the distance from the target surface and the fluence of the ablation lasers. The experimental TOF measurements were carried out for lithium neutral (670.8 nm and 610.3 nm), and ionic (548.4 nm and 478.8 nm) lines. These experimental observations have been compared with that for single pulse laser ablation mode. It is found that depending on the fluence and laser pulse shape of the first pre-ablation laser and the second main ablation laser, the plasma plume formation and its characteristic features can be described in terms of plume-plume or laser-plume interaction processes. Moreover, the enhancement in the intensity of Li neutral and ionic lines is observed when the laser-plume interaction is the dominant process. Here, we see the evidence of the role of inverse Bremsstrahlung absorption process in the initial stage of formation of lithium plasma in this case.

  7. Comparative study of structural and optical properties of pulsed and RF plasma polymerized aniline films

    Energy Technology Data Exchange (ETDEWEB)

    Barman, Tapan; Pal, Arup R., E-mail: arpal@iasst.gov.in; Chutia, Joyanti

    2014-09-15

    Graphical abstract: - Highlights: • Pulse DC and RF plasma is used for synthesis of conducting polymer films. • Conjugated structure retention is better at optimum powers in both the processes. • Conjugated structure retention is better in case of RF plasma prepared films. • Band gap is lower in case of RF plasma prepared films at higher power. • Defect in pulse plasma prepared film is less than RF plasma prepared thin films. - Abstract: Plasma polymerization of aniline is carried out by means of continuous RF and pulsed DC glow discharge plasma in a common reactor at different applied powers. The discharge control variables are optimized for good quality film growth and the role of fragmentation of the molecular structure on the structural, optical, morphological and optophysical properties of the deposited plasma polymerized aniline (PPAni) layers is investigated. Retention of the conjugated structure is found to be prominent at optimum applied power to the plasma in both the continuous RF and pulsed DC polymerization techniques. Improvement in conjugated structure and chain length have been observed in both the continuous RF and pulse DC PPAni thin films with the increase in applied power to the plasma up to a certain limit of applied power when working pressure is fixed at 0.15 mbar. A decrease in optical bandgap with the increase in applied power to the plasma is observed in both the pulsed DC and RF PPAni thin films, but it is more significant in case of RF PPAni films. The plasma polymerized aniline thin films are found to emit photoluminescence due to band to band transition and defects generated in the structure.

  8. Further study of CdWO4 crystal scintillators as detectors for high sensitivity double beta experiments: scintillation properties and pulse-shape discrimination

    CERN Document Server

    Bardelli, L; Bizzeti, P G; Carraresi, L; Danevich, F A; Fazzini, T F; Grinyov, B V; Ivannikova, N V; Kobychev, V V; Kropivyansky, B N; Maurenzig, P R; Nagornaya, L L; Nagorny, S S; Nikolaiko, A S; Pavlyuk, A A; Poda, D V; Solsky, I M; Sopinskyy, M V; Stenin, Y G; Taccetti, F; Tretyak, V I; Vasiliev, Y V; Yurchenko, S S; Stenin, Yu. G.; Vasiliev, Ya. V.

    2006-01-01

    Energy resolution, light yield, non-proportionality in the scintillation response, alpha/beta ratio, pulse shape for gamma rays and alpha particles were studied with CdWO4 crystal scintillators. Some indication for a difference in the emission spectra for gamma rays and alpha particles was observed. No dependence of CdWO4 pulse shape on emission spectrum wavelengths under laser, alpha particles and gamma ray excitation was observed. Dependence of scintillation pulse shape for gamma quanta and alpha particles and pulse-shape discrimination ability on temperature was measured in the range of 0-24 degrees.

  9. Further study of CdWO{sub 4} crystal scintillators as detectors for high sensitivity 2{beta} experiments: Scintillation properties and pulse-shape discrimination

    Energy Technology Data Exchange (ETDEWEB)

    Bardelli, L. [Dipartimento di Fisica, Universita di Firenze and INFN, 50019 Florence (Italy); Bini, M. [Dipartimento di Fisica, Universita di Firenze and INFN, 50019 Florence (Italy); Bizzeti, P.G. [Dipartimento di Fisica, Universita di Firenze and INFN, 50019 Florence (Italy); Carraresi, L. [Dipartimento di Fisica, Universita di Firenze and INFN, 50019 Florence (Italy); Danevich, F.A. [Institute for Nuclear Research, MSP 03680 Kiev (Ukraine)]. E-mail: danevich@kinr.kiev.ua; Fazzini, T.F. [Dipartimento di Fisica, Universita di Firenze and INFN, 50019 Florence (Italy); Grinyov, B.V. [Institute for Scintillation Materials, 61001 Kharkov (Ukraine); Ivannikova, N.V. [Nikolaev Institute of Inorganic Chemistry, 630090 Novosibirsk (Russian Federation); Kobychev, V.V. [Institute for Nuclear Research, MSP 03680 Kiev (Ukraine); Kropivyansky, B.N. [Institute for Nuclear Research, MSP 03680 Kiev (Ukraine); Maurenzig, P.R. [Dipartimento di Fisica, Universita di Firenze and INFN, 50019 Florence (Italy); Nagornaya, L.L. [Institute for Scintillation Materials, 61001 Kharkov (Ukraine); Nagorny, S.S. [Institute for Nuclear Research, MSP 03680 Kiev (Ukraine); Nikolaiko, A.S. [Institute for Nuclear Research, MSP 03680 Kiev (Ukraine); Pavlyuk, A.A. [Nikolaev Institute of Inorganic Chemistry, 630090 Novosibirsk (Russian Federation); Poda, D.V. [Institute for Nuclear Research, MSP 03680 Kiev (Ukraine); Solsky, I.M. [Institute for Materials, 79031 Lviv (Ukraine); Sopinskyy, M.V. [Lashkaryov Institute of Semiconductor Physics, 03028 Kiev (Ukraine); Stenin, Yu.G. [Nikolaev Institute of Inorganic Chemistry, 630090 Novosibirsk (Russian Federation); Taccetti, F. [Dipartimento di Fisica, Universita di Firenze and INFN, 50019 Florence (Italy); Tretyak, V.I.; Yurchenko, S.S. [Institute for Nuclear Research, MSP 03680 Kiev (Ukraine); Vasiliev, Ya.V. [Nikolaev Institute of Inorganic Chemistry, 630090 Novosibirsk (Russian Federation)

    2006-12-21

    Energy resolution, non-proportionality in the scintillation response, {alpha}/{beta} ratio, pulse shape for {gamma} rays and {alpha} particles were studied with CdWO{sub 4} crystal scintillators. Some indication for a difference in the emission spectra for {gamma} rays and {alpha} particles was observed. No dependence of CdWO{sub 4} pulse shape on emission spectrum wavelengths under laser, {alpha} particles and {gamma} ray excitation was observed. Dependence of scintillation pulse shape for {gamma} quanta and {alpha} particles and pulse-shape discrimination ability on temperature was measured in the range of 0-24{sup o}C.

  10. Experiment Study of Dual Wavelength and Dual Pulse Q-switched Intracavity Frequency Doubling of a Tunable Cr:LiSAF Laser

    Institute of Scientific and Technical Information of China (English)

    CHEN Changshui; WANG Peilin; XIE Jianping; SHI Dufang; SHA Xianwu; HE Yulong

    2001-01-01

    In this paper, a flashlamp-pumped Q-switched Cr: LiSAF laser system with intracavity frequency doubling is designed to obtain dual pulse and dual wavelength laser output. The behaviors of second harmonic output of dual pulse and dual wavelength are studied experimentally. Good results are obtained in experiments: the output energy of each second harmonic pulse a round 448.1 nm is 10.2 mJ, the dual pulse time interval can be tuned widely, and the tunable range of each second harmonic wavelength is 448.1 to 465 nm.

  11. Study on self-frequency-shift of femtosecond pulse in nonlinear dispersion medium using time-resolved cross-phase modulation method

    Institute of Scientific and Technical Information of China (English)

    赵应桥; 朱鹤元; 刘建华; 孙迭篪; 李富铭

    1997-01-01

    A time-resolved cross-phase modulation method combined with a modified nonlinear Schrodinger equation is used to study the effects of nonlinear response time on the propagation of ultrashort pulses in nonlinear dispersion media. Evolution of cross-phase modulation spectrum with the different time delay between the probe pulse and pump pulse is simulated using split-step Fourier method. It is shown that both normal self-frequency-shift-red-shift and abnormal self-frequency-shift-blue-shift can occur in the frequency domain for the probe pulse, and a satisfactory theoretical interpretation is given.

  12. Numerical Study of Concentration and Thermocapillary Melt Convection under Pulsed Laser Alloying

    Science.gov (United States)

    Kovalev, O. B.; Popov, A. N.; Smirnova, E. M.; Smurov, I.

    The mathematical model of capillary thermal-concentration convection is proposed; on its basis, a numerical simulation of the process of metal surface alloying with the aid of pulse laser radiation was done. The influence of the pulse intensity on melt hydrodynamics and distribution of the alloying substance was evaluated. In the published works on this theme results of researches are not full enough and the extremely limited. For the substrate material, the data of titanium and iron were used, including the dependence of the surface tension on the melt temperature and admixture concentration.

  13. PERFORMANCE STUDIES OF CDZNTE DETECTOR BY USING A PULSE SHAPE ANALYSIS.

    Energy Technology Data Exchange (ETDEWEB)

    BOLOTNIKOV, A.

    2005-07-31

    Pulse shape analysis is proved to be a powerful tool to characterize the performance of CdZnTe devices and understand their operating principles. It allows one to investigate the device configurations, electron transport properties, effects governing charge collection, electric-field distributions, signal charge formation, etc. This work describes an application of different techniques based on the pulse shape measurements to characterize pixel, coplanar-grid, and virtual Frisch-grid devices and understand the electronic properties of CZT material provided by different vendors. We report new results that may explain the performance limits of these devices.

  14. A pulse radiolysis study of the dynamics of ascorbic acid free radicals within a liposomal environment.

    Science.gov (United States)

    Kobayashi, Kazuo; Seike, Yumiko; Saeki, Akinori; Kozawa, Takahiro; Takeuchi, Fusako; Tsubaki, Motonari

    2014-10-06

    The dynamics of free-radical species in a model cellular system are examined by measuring the formation and decay of ascorbate radicals within a liposome with pulse radiolysis techniques. Upon pulse radiolysis of an N2O-saturated aqueous solution containing ascorbate-loaded liposome vesicles, ascorbate radicals are formed by the reaction of OH(·) radicals with ascorbate in unilamellar vesicles exclusively, irrespective of the presence of vesicle lipids. The radicals are found to decay rapidly compared with the decay kinetics in an aqueous solution. The distinct radical reaction kinetics in the vesicles and in bulk solution are characterized, and the kinetic data are analyzed.

  15. Study on laser welding of austenitic stainless steel by varying incident angle of pulsed laser beam

    Science.gov (United States)

    Kumar, Nikhil; Mukherjee, Manidipto; Bandyopadhyay, Asish

    2017-09-01

    In the present work, AISI 304 stainless steel sheets are laser welded in butt joint configuration using a robotic control 600 W pulsed Nd:YAG laser system. The objective of the work is of twofold. Firstly, the study aims to find out the effect of incident angle on the weld pool geometry, microstructure and tensile property of the welded joints. Secondly, a set of experiments are conducted, according to response surface design, to investigate the effects of process parameters, namely, incident angle of laser beam, laser power and welding speed, on ultimate tensile strength by developing a second order polynomial equation. Study with three different incident angle of laser beam 89.7 deg, 85.5 deg and 83 deg has been presented in this work. It is observed that the weld pool geometry has been significantly altered with the deviation in incident angle. The weld pool shape at the top surface has been altered from semispherical or nearly spherical shape to tear drop shape with decrease in incident angle. Simultaneously, planer, fine columnar dendritic and coarse columnar dendritic structures have been observed at 89.7 deg, 85.5 deg and 83 deg incident angle respectively. Weld metals with 85.5 deg incident angle has higher fraction of carbide and δ-ferrite precipitation in the austenitic matrix compared to other weld conditions. Hence, weld metal of 85.5 deg incident angle achieved higher micro-hardness of ∼280 HV and tensile strength of 579.26 MPa followed by 89.7 deg and 83 deg incident angle welds. Furthermore, the predicted maximum value of ultimate tensile strength of 580.50 MPa has been achieved for 85.95 deg incident angle using the developed equation where other two optimum parameter settings have been obtained as laser power of 455.52 W and welding speed of 4.95 mm/s. This observation has been satisfactorily validated by three confirmatory tests.

  16. Self-enhancement processing in the default network: a single-pulse TMS study.

    Science.gov (United States)

    Luber, Bruce; Lou, Hans C; Keenan, Julian P; Lisanby, Sarah H

    2012-11-01

    Much research has been done on positive self-evaluation and its relationship to mental health. However, little is known about its neural underpinnings. Imaging studies have suggested that the brain's default network is involved with self-related processing and that one portion of the default network, medial prefrontal cortex (MPFC), is particularly involved with self-evaluation. Here, we used transcranial magnetic stimulation (TMS) to causally demonstrate that this network, and particularly MPFC, is involved with self-evaluative processing. In a first experiment, 27 healthy volunteers judged whether adjectives, evenly divided between desirable and undesirable traits, described themselves or their best friends, and a robust self-enhancement bias effect was found. In a second experiment, single-pulse TMS was applied targeting three locations (MPFC and left and right parietal cortex) in a different group of healthy volunteers while they performed the adjective task. In each trial, TMS was applied at one of five different times relative to onset of the adjective ranging from 0 to 480 ms. TMS affected self-enhancement bias in a site- and latency-specific manner: at MPFC, the self-enhancement bias actually reversed at 160 ms, with subjects favoring their best friend over themselves. TMS may thus be of use in investigating areas of mental illness in which self-evaluation is abnormal, potentially as a diagnostic tool. In addition, the present study, combined with our previous reports (Lou et al., Proc Natl Acad Sci USA 101(17):6827-6832, 2004, Exp Brain Res 207:27-38, 2010), causally demonstrates two kinds of self-related processing within the default network, one centered in parietal cortex and concerned with retrieval of self-related associations, and the other MPFC-centered and involved in self-evaluative processing.

  17. A portable high-field pulsed-magnet system for single-crystal x-ray scattering studies.

    Science.gov (United States)

    Islam, Zahirul; Ruff, Jacob P C; Nojiri, Hiroyuki; Matsuda, Yasuhiro H; Ross, Kathryn A; Gaulin, Bruce D; Qu, Zhe; Lang, Jonathan C

    2009-11-01

    We present a portable pulsed-magnet system for x-ray studies of materials in high magnetic fields (up to 30 T). The apparatus consists of a split-pair of minicoils cooled on a closed-cycle cryostat, which is used for x-ray diffraction studies with applied field normal to the scattering plane. A second independent closed-cycle cryostat is used for cooling the sample to near liquid helium temperatures. Pulsed magnetic fields (approximately 1 ms in total duration) are generated by discharging a configurable capacitor bank into the magnet coils. Time-resolved scattering data are collected using a combination of a fast single-photon counting detector, a multichannel scaler, and a high-resolution digital storage oscilloscope. The capabilities of this instrument are used to study a geometrically frustrated system revealing strong magnetostrictive effects in the spin-liquid state.

  18. Self-specific processing in the default network: a single-pulse TMS study.

    Science.gov (United States)

    Lou, Hans C; Luber, Bruce; Stanford, Arielle; Lisanby, Sarah H

    2010-11-01

    In examining neural processing specific to the self, primarily by contrasting self-related stimuli with non-self-related stimuli (i.e., self vs. other), neuroimaging studies have activated a consistent set of regions, including medial prefrontal cortex (MPFC), precuneus, and right and left inferior parietal cortex. However, criticism has arisen that this network may not be specific to self-related processing, but instead reflects a more general aspect of cortical processing. For example, it is almost identical to the active network of the resting state, the "default" mode, when the subject is free to think about anything at all. We tested the self-specificity of this network by using transcranial magnetic stimulation (TMS) to briefly disrupt local cortical processing while subjects rated adjectives as like or unlike themselves or their best friend. Healthy volunteers show a self-reference effect (SRE) in this task, in which performance with self-related items is superior to that with other-related items. As individual adjectives appeared on a monitor, single-pulse TMS was applied at five different times relative to stimulus onset (SOA: stimulus onset asynchrony) ranging from 0 to 480 ms. In 18 subjects, TMS to left parietal cortex suppressed the SRE from 160 to 480 ms. SRE suppression occurred at later SOA with TMS to the right parietal cortex. In contrast, no effects were seen with TMS to MPFC. Together with our previous work, these results provide evidence for a self-specific processing system in which midline and lateral inferior parietal cortices, as elements of the default network, play a role in ongoing self-awareness.

  19. Template Reproduction of GRB Pulse Light Curves

    Science.gov (United States)

    Hakkila, Jon E.; Preece, R. D.; Loredo, T. J.; Wolpert, R. L.; Broadbent, M. E.

    2014-01-01

    A study of well-isolated pulses in gamma ray burst light curves indicates that simple models having smooth and monotonic pulse rises and decays are inadequate. Departures from the Norris et al. (2005) pulse shape are in the form of a wave-like pre-peak residual that is mirrored and stretched following the peak. Pulse shape departures are present in GRB pulses of all durations, but placement of the departures relative to pulse peaks correlates with asymmetry. This establishes an additional link between temporal structure and spectral evolution, as pulse asymmetry is related to initial hardness while pulse duration indicates the rate of hard-to-soft pulse evolution.

  20. Magnetic Resonance Studies of Proton Loss from Carotenoid Radical Cations

    Energy Technology Data Exchange (ETDEWEB)

    Kispert, Lowell D [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Focsan, A Ligia [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Konovalova, Tatyana A [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Lawrence, Jesse [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Bowman, Michael K [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Dixon, David A [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Molnar, Peter [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Deli, Jozsef [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2007-06-11

    Carotenoids, intrinsic components of reaction centers and pigment-protein complexes in photosynthetic membranes, play a photoprotective role and serve as a secondary electron donor. Before optimum use of carotenoids can be made in artificial photosynthetic systems, their robust nature in living materials requires extensive characterization of their electron transfer, radical trapping ability, stability, structure in and on various hosts, and photochemical behavior. Pulsed ENDOR and 2D-HYSCORE studies combined with DFT calculations reveal that photo-oxidation of natural zeaxanthin (I) and violaxanthin (II) on silica-alumina produces not only the carotenoid radical cations (Car•+) but also neutral radicals (#Car•) by proton loss from the methyl groups at positions 5 or 5', and possibly 9 or 9' and 13 or 13'. Notably, the proton loss favored in I at the 5 position by DFT calculations, is unfavorable in II due to the epoxide at the 5, 6 position. DFT calculations predict the isotropic methyl proton couplings of 8-10 MHz for Car•+ which agree with the ENDOR for carotenoid α-conjugated radical cations. Large α-proton hyperfine coupling constants (>10 MHz) determined from HYSCORE are assigned from the DFT calculations to neutral carotenoid radicals. Proton loss upon photolysis was also examined as a function of carotenoid polarity [Lycopene (III) versus 8'-apo-β-caroten-8'-al (IV)]; hydrogen bonding [Lutein (V) versus III]; host [silica-alumina versus MCM-41 molecular sieve]; and substituted metal in MCM-41. Loss of H+ from the 5(5'), 9(9') or 13(13') methyl positions has importance in photoprotection. Photoprotection involves nonphotochemical quenching (NPQ) in which 1Ch1* decays via energy transfer to the carotenoid which returns to the ground state by thermal dissipation; or via electron transfer to form a charge transfer state (I •+…Chl•-), lower in energy than 1Chl*. Formation of I •+ results in bond

  1. Experimental study on dielectric barrier discharge actuators operating in pulse mode

    NARCIS (Netherlands)

    Kotsonis, M.; Veldhuis, L.

    2010-01-01

    An experimental investigation is performed on the operation of dielectric barrier discharge plasma actuators used as manipulators of secondary and unsteady flow structures such as boundary layer instabilities or shedding vortices. The actuators are tested mainly in pulse mode. High sample rate hot-w

  2. Comparative study of pulsed laser cleaning applied to weathered marble surfaces

    Science.gov (United States)

    Ortiz, P.; Antúnez, V.; Ortiz, R.; Martín, J. M.; Gómez, M. A.; Hortal, A. R.; Martínez-Haya, B.

    2013-10-01

    The removal of unwanted matter from surface stones is a demanding task in the conservation of cultural heritage. This paper investigates the effectiveness of near-infrared (IR) and ultraviolet (UV) laser pulses for the cleaning of surface deposits, iron oxide stains and different types of graffiti (black, red and green sprays and markers, and black cutting-edge ink) on dolomitic white marble. The performance of the laser techniques is compared to common cleaning methods on the same samples, namely pressurized water and chemical treatments. The degree of cleaning achieved with each technique is assessed by means of colorimetric measurements and X-ray microfluorescence. Eventual morphological changes induced on the marble substrate are monitored with optical and electronic microscopy. It is found that UV pulsed laser ablation at 266 nm manages to clean all the stains except the cutting-edge ink, although some degree of surface erosion is produced. The IR laser pulses at 1064 nm can remove surface deposits and black spray acceptably, but a yellowing is observed on the stone surface after treatment. An economic evaluation shows that pulsed laser cleaning techniques are advantageous for the rapid cleaning of small or inaccessible surface areas, although their extensive application becomes expensive due to the long operating times required.

  3. Experimental study on ultrasonic pulse velocity evaluation of the microstructure of cementitious material at early age

    NARCIS (Netherlands)

    Guang Ye; Van Breugel, K.; Fraaij, A.L.A.

    2001-01-01

    This paper describes an ultrasonic experimental set-up to monitor the development of the microstructure of fresh concrete at different temperatures (isothermal curing at 10, 20, 30 and 50 °C) and water/cement ratios (0.40, 0.45 and 0.55). The Ultrasonic Pulse Velocity (UPV) is used as an indication

  4. Microscopy study of ripples created on steel surface by use of ultra short laser pulses

    NARCIS (Netherlands)

    Vincenc Obona, J.; Ocelik, V.; Visser, B.; Visser, B.; de Hosson, J.Th.M.; Skolski, J.Z.P.; Mitko, S.; Mitko, V.S.; Römer, Gerardus Richardus, Bernardus, Engelina; Huis in 't Veld, Bert

    2010-01-01

    This paper concentrates on ripples on the surface of steel that arise from lasermaterial interaction. In particular we have observed two different sets of ripples on steel samples that were machined by 210 fs laser pulses with 800 nm wavelength at normal incidence. Small ripples were found with

  5. Experimental study on ultrasonic pulse velocity evaluation of the microstructure of cementitious material at early age

    NARCIS (Netherlands)

    Guang Ye; Van Breugel, K.; Fraaij, A.L.A.

    2001-01-01

    This paper describes an ultrasonic experimental set-up to monitor the development of the microstructure of fresh concrete at different temperatures (isothermal curing at 10, 20, 30 and 50 °C) and water/cement ratios (0.40, 0.45 and 0.55). The Ultrasonic Pulse Velocity (UPV) is used as an indication

  6. A comparison study of on-chip short pulse generation circuits based on a coplanar waveguide

    Institute of Scientific and Technical Information of China (English)

    邹焕; 耿永涛; 王平山; 李家胤

    2011-01-01

    A few traditional pulse-forming circuits are implemented in a commercial 0.13 μm digital complementary-metal-oxide-semiconductor (CMOS) technology. These circuits, based on a coplanar waveguide, are analyzed and compared through CadenceTM Spectre simulati

  7. Design study of a 60T pulsed magnet with 10 mu s risetime

    NARCIS (Netherlands)

    Li, L.; Van Bockstal, L.; Herlach, F.; van Amersfoort, W.

    1996-01-01

    A 60 T nondestructive pulsed magnet for the ''Free Electron Laser for;Infrared Experiments'' (FELIX) is developed. As a rise time of 10 mu s is required, the magnet is designed consisting of two coils in order to cope with the skin effect and power requirements. Each of the coils

  8. Experimental studies of axial magnetic fields generated in ultrashort-pulse laser-plasma interaction

    Institute of Scientific and Technical Information of China (English)

    李玉同; 张杰; 陈黎明; 赵理曾; 夏江帆; 魏志义; 江文勉

    2000-01-01

    The quasistatic axial magnetic fields in plasmas produced by ultrashort laser pulses were measured by measuring the Faraday rotation angle of the backscattered emission. The spatial distribution of the axial magnetic field was obtained with a peak value as high as 170 Tesla. Theory suggests that the axial magnetic field is generated by dynamo effect in laser-plasma interaction.

  9. Reactivity of OH and O– with aqueous methyl viologen studied by pulse radiolysis

    DEFF Research Database (Denmark)

    Solar, Sonja; Solar, Wolfgang; Getoff, Nikola

    1985-01-01

    The behaviour of aqueous MV2+ towards oxidizing radicals (OH and O–) has been investigated in the pH range from 6 to 14 by means of pulse radiolysis. A semi-linear optimization method was applied for resolving the complex reaction mechanism. In the pH range from 6 to 8 the rate constant for attac...

  10. Study of laser die release by Q-switched Nd:YAG laser pulses

    NARCIS (Netherlands)

    Karlitskaya, N.; de Lange, D.F.; Meijer, J.; Sanders, Rene; Phipps, Claude R.

    2004-01-01

    A new laser-assisted process called "Laser Die Transfer" is developed for high speed assembling of miniature electronic components. Silicon dies, fabricated on an optically transparent carrier are released using a laser pulse. This process has the potential to offer major advantages compared to

  11. Anharmonic resonance absorption of short laser pulses in clusters: A molecular dynamics simulation study

    Science.gov (United States)

    Mahalik, S. S.; Kundu, M.

    2016-12-01

    Linear resonance (LR) absorption of an intense 800 nm laser light in a nano-cluster requires a long laser pulse >100 fs when Mie-plasma frequency ( ω M ) of electrons in the expanding cluster matches the laser frequency (ω). For a short duration of the pulse, the condition for LR is not satisfied. In this case, it was shown by a model and particle-in-cell (PIC) simulations [Phys. Rev. Lett. 96, 123401 (2006)] that electrons absorb laser energy by anharmonic resonance (AHR) when the position-dependent frequency Ω [ r ( t ) ] of an electron in the self-consistent anharmonic potential of the cluster satisfies Ω [ r ( t ) ] = ω . However, AHR remains to be a debate and still obscure in multi-particle plasma simulations. Here, we identify AHR mechanism in a laser driven cluster using molecular dynamics (MD) simulations. By analyzing the trajectory of each MD electron and extracting its Ω [ r ( t ) ] in the self-generated anharmonic plasma potential, it is found that electron is outer ionized only when AHR is met. An anharmonic oscillator model, introduced here, brings out most of the features of MD electrons while passing the AHR. Thus, we not only bridge the gap between PIC simulations, analytical models, and MD calculations for the first time but also unequivocally prove that AHR process is a universal dominant collisionless mechanism of absorption in the short pulse regime or in the early time of longer pulses in clusters.

  12. Study on technology of high-frequency pulsed magnetic field strength measurement.

    Science.gov (United States)

    Chen, Yi-Mei; Liu, Zhi-Peng; Yin, Tao

    2012-01-01

    High-frequency transient weak magnetic field is always involved in researches about biomedical engineering field while common magnetic-field sensors cannot work properly at frequencies as high as MHz. To measure the value of MHz-level weak pulsed magnetic-field strength accurately, this paper designs a measurement and calibration method for pulsed magnetic-field. In this paper, a device made of Nonferromagnetic material was independently designed and applied to pulsed magnetic field measurement. It held an accurately relative position between the magnetic field generating coil and the detecting coil. By applying a sinusoidal pulse to the generator, collecting the induced electromotive force of the detector, the final magnetic field strength was worked out through algorithms written in Matlab according to Faraday's Law. Experiments were carried out for measurement and calibration. Experiments showed that, under good stability and consistency, accurate measurement of magnetic-field strength of a sinepulse magnetic-field can be achieved, with frequency at 0.5, 1, 1.5 MHz and strength level at micro-Tesla. Calibration results carried out a measuring relative error about 2.5%.

  13. Comparative study of pulsed laser cleaning applied to weathered marble surfaces

    Energy Technology Data Exchange (ETDEWEB)

    Ortiz, P., E-mail: mportcal@upo.es [Department of Physical, Chemical and Natural Systems, Universidad Pablo de Olavide, 41013 Seville (Spain); Antúnez, V.; Ortiz, R.; Martín, J.M. [Department of Physical, Chemical and Natural Systems, Universidad Pablo de Olavide, 41013 Seville (Spain); Gómez, M.A. [Instituto Andaluz de Patrimonio Histórico, Camino de los Descubrimientos s/n, 41092 Seville (Spain); Hortal, A.R.; Martínez-Haya, B. [Department of Physical, Chemical and Natural Systems, Universidad Pablo de Olavide, 41013 Seville (Spain)

    2013-10-15

    The removal of unwanted matter from surface stones is a demanding task in the conservation of cultural heritage. This paper investigates the effectiveness of near-infrared (IR) and ultraviolet (UV) laser pulses for the cleaning of surface deposits, iron oxide stains and different types of graffiti (black, red and green sprays and markers, and black cutting-edge ink) on dolomitic white marble. The performance of the laser techniques is compared to common cleaning methods on the same samples, namely pressurized water and chemical treatments. The degree of cleaning achieved with each technique is assessed by means of colorimetric measurements and X-ray microfluorescence. Eventual morphological changes induced on the marble substrate are monitored with optical and electronic microscopy. It is found that UV pulsed laser ablation at 266 nm manages to clean all the stains except the cutting-edge ink, although some degree of surface erosion is produced. The IR laser pulses at 1064 nm can remove surface deposits and black spray acceptably, but a yellowing is observed on the stone surface after treatment. An economic evaluation shows that pulsed laser cleaning techniques are advantageous for the rapid cleaning of small or inaccessible surface areas, although their extensive application becomes expensive due to the long operating times required.

  14. Multicenter Study Validating Accuracy of a Continuous Respiratory Rate Measurement Derived From Pulse Oximetry: A Comparison With Capnography

    Science.gov (United States)

    Bergese, Sergio D.; Kelley, Scott D.; McIntyre, Robert; Uribe, Alberto A.; Sethi, Rakesh; Watson, James N.; Addison, Paul S.

    2017-01-01

    BACKGROUND: Intermittent measurement of respiratory rate via observation is routine in many patient care settings. This approach has several inherent limitations that diminish the clinical utility of these measurements because it is intermittent, susceptible to human error, and requires clinical resources. As an alternative, a software application that derives continuous respiratory rate measurement from a standard pulse oximeter has been developed. We sought to determine the performance characteristics of this new technology by comparison with clinician-reviewed capnography waveforms in both healthy subjects and hospitalized patients in a low-acuity care setting. METHODS: Two independent observational studies were conducted to validate the performance of the Medtronic NellcorTM Respiration Rate Software application. One study enrolled 26 healthy volunteer subjects in a clinical laboratory, and a second multicenter study enrolled 53 hospitalized patients. During a 30-minute study period taking place while participants were breathing spontaneously, pulse oximeter and nasal/oral capnography waveforms were collected. Pulse oximeter waveforms were processed to determine respiratory rate via the Medtronic Nellcor Respiration Rate Software. Capnography waveforms reviewed by a clinician were used to determine the reference respiratory rate. RESULTS: A total of 23,243 paired observations between the pulse oximeter-derived respiratory rate and the capnography reference method were collected and examined. The mean reference-based respiratory rate was 15.3 ± 4.3 breaths per minute with a range of 4 to 34 breaths per minute. The Pearson correlation coefficient between the Medtronic Nellcor Respiration Rate Software values and the capnography reference respiratory rate is reported as a linear correlation, R, as 0.92 ± 0.02 (P Medtronic Nellcor Respiration Rate Software was 0.18 breaths per minute with a precision (SD) of 1.65 breaths per minute (healthy volunteers: 0.37 ± 0

  15. Study of the expansion characteristics of a pulsed plasma jet in air

    Science.gov (United States)

    Zhao, Xuewei; Yu, Yonggang; Mang, Shanshan; Xue, Xiaochun

    2017-04-01

    In the background of electrothermal-chemical (ETC) emission, an investigation has been conducted on the characteristics of a freely expanding pulsed plasma jet in air. The evolutionary process of the plasma jet is experimentally investigated using a piezoelectric pressure sensor and a digital high-speed video system. The variation relation in the extended volume, axial displacement and radial displacement of the pulsed plasma jet in atmosphere with time under different discharge voltages and jet breaking pressures is obtained. Based on experiments, a two-dimensional axisymmetric unsteady model is established to analyze the characteristics of the two-phase interface and the variation of flow-field parameters resulting from a pulsed plasma jet into air at a pressure of 1.5-3.5 MPa under three nozzle diameters (3 mm, 4 mm and 5 mm, respectively). The images of the plasma jet reveal a changing shape process, from a quasi-ellipsoid to a conical head and an elongated cylindrical tail. The axial displacement of the jet is always larger than that along the radial direction. The extended volume reveals a single peak distribution with time. Compared to the experiment, the numerical simulation agrees well with the experimental data. The parameters of the jet field mutate at the nozzle exit with a decrease in the parameter pulse near the nozzle, and become more and more gradual and close to environmental parameters. Increasing the injection pressure and nozzle diameter can increase the parameters of the flow field such as the expansion volume of the pulsed plasma jet, the size of the Mach disk and the pressure. In addition, the turbulent mixing in the expansion process is also enhanced.

  16. Advanced numerical studies of the neutralized drift compression of intense ion beam pulses

    Directory of Open Access Journals (Sweden)

    Adam B. Sefkow

    2007-10-01

    Full Text Available Longitudinal bunch compression of intense ion beams for warm dense matter and heavy ion fusion applications occurs by imposing an axial velocity tilt onto an ion beam across the acceleration gap of a linear induction accelerator, and subsequently allowing the beam to drift through plasma in order to neutralize its space-charge and current as the pulse compresses. The detailed physics and implications of acceleration gap effects and focusing aberration on optimum longitudinal compression are quantitatively reviewed using particle-in-cell simulations, showing their dependence on many system parameters. Finite-size gap effects are shown to result in compression reduction, due to an increase in the effective longitudinal temperature imparted to the beam, and a decrease in intended fractional tilt. Sensitivity of the focal plane quality to initial longitudinal beam temperature is explored, where slower particles are shown to experience increased levels of focusing aberration compared to faster particles. A plateau effect in axial compression is shown to occur for larger initial pulse lengths, where the increases in focusing aberration over the longer drift lengths involved dominate the increases in relative compression, indicating a trade-off between current compression and pulse duration. The dependence on intended fractional tilt is also discussed and agrees well with theory. A balance between longer initial pulse lengths and larger tilts is suggested, since both increase the current compression, but have opposite effects on the final pulse length, drift length, and amount of longitudinal focusing aberration. Quantitative examples are outlined that explore the sensitive dependence of compression on the initial kinetic energy and thermal distribution of the beam particles. Simultaneous transverse and longitudinal current density compression can be achieved in the laboratory using a strong final-focus solenoid, and simulations addressing the effects

  17. Experimental study of direct laser deposition of Ti-6Al-4V and Inconel 718 by using pulsed parameters.

    Science.gov (United States)

    Shah, Kamran; Izhar Ul Haq; Shah, Shaukat Ali; Khan, Farid Ullah; Khan, Muhammad Tahir; Khan, Sikander

    2014-01-01

    Laser direct metal deposition (LDMD) has developed from a prototyping to a single metal manufacturing tool. Its potential for creating multimaterial and functionally graded structures is now beginning to be explored. This work is a first part of a study in which a single layer of Inconel 718 is deposited on Ti-6Al-4V substrate. Single layer tracks were built at a range of powder mass flow rates using a coaxial nozzle and 1.5 kW diode laser operating in both continuous and pulsed beam modes. This part of the study focused on the experimental findings during the deposition of Inconel 718 powder on Ti-6Al-4V substrate. Scanning electron microscopy (SEM) and X-ray diffraction analysis were performed for characterization and phase identification. Residual stress measurement had been carried out to ascertain the effects of laser pulse parameters on the crack development during the deposition process.

  18. Experimental Study of Direct Laser Deposition of Ti-6Al-4V and Inconel 718 by Using Pulsed Parameters

    Directory of Open Access Journals (Sweden)

    Kamran Shah

    2014-01-01

    Full Text Available Laser direct metal deposition (LDMD has developed from a prototyping to a single metal manufacturing tool. Its potential for creating multimaterial and functionally graded structures is now beginning to be explored. This work is a first part of a study in which a single layer of Inconel 718 is deposited on Ti-6Al-4V substrate. Single layer tracks were built at a range of powder mass flow rates using a coaxial nozzle and 1.5 kW diode laser operating in both continuous and pulsed beam modes. This part of the study focused on the experimental findings during the deposition of Inconel 718 powder on Ti-6Al-4V substrate. Scanning electron microscopy (SEM and X-ray diffraction analysis were performed for characterization and phase identification. Residual stress measurement had been carried out to ascertain the effects of laser pulse parameters on the crack development during the deposition process.

  19. Study of bipolar pulsed plasma electrolytic carbonitriding on nanostructure of compound layer for a gamma Ti-Al alloy

    Institute of Scientific and Technical Information of China (English)

    Mahmood ALIOFKHAZRAEI; Alireza SABOUR ROUHAGHDAM; Mohsen ROOHZENDEH

    2008-01-01

    The surface hardening of a gamma Ti-Al alloy by using bipolar pulsed nanocrystalline plasma electro-lytic carbonitriding has been studied in this investigation. Coating process was performed on a triethanolamine-based electrolyte by a cooling bath. The nanostructure of the obtained compound layer was examined with the figure analysis of the scanning electron microscopy (SEM) nanographs. The effects of the process variables, i.e., fre-quency, temperature of the electrolyte, applied voltage and treatment time, have been experimentally studied. Statistical methods were used to achieve the optimum size of the nanocrystals. Finally, the contribution percentage of the effective factors of the pulsed current was revealed, and the confirmation run showed the validity of the obtained results.

  20. Study on the Microsecond Pulse Homogeneous Dielectric Barrier Discharges in Atmospheric Air and Its Influencing Factors%Study on the Microsecond Pulse Homogeneous Dielectric Barrier Discharges in Atmospheric Air and Its Influencing Factors

    Institute of Scientific and Technical Information of China (English)

    方志; 雷枭; 蔡玲玲; 邱毓昌; Edmund KUFFEL

    2011-01-01

    The homogeneous dielectric barrier discharge (DBD) in atmospheric air between two symmetric-columnar copper electrodes with epoxy plates as the dielectric barriers is generated using a us pulse high voltage power supply. The discharge characteristics are studied by measurement of its electrical discharge parameters and observation of its light emission phenom- ena, and the main discharge parameters of the homogenous DBD, such as discharge current and average discharge power, are calculated. Results show that the discharge generated is a homogeneous one with one larger single current pulse of about 2 #s duration appearing in each voltage pulse, and its light emission is radially homogeneous and covers the entire surface of the two elec- trodes. The influences of applied voltage amplitude, air gap distance and barrier thickness on the transition of discharge modes are studied. With the increase of air gap distance, the discharge will transit from homogeneous mode to filamentary mode. The higher the thickness of dielectric barriers, the larger the air gap distance for generating the homogeneous discharge mode. The average discharge power increases non-linearly with increasing applied voltage amplitude, and decreases non-linearly with the increase of air gap distance and barrier thickness. In order to generate stable and homogeneous DBD with high discharge power, thin barriers distance should be used, and higher applied voltage amplitude should be applied to small air gap.

  1. Effectiveness of Intense Pulsed Light treatment in solar lentigo: a retrospective study

    Directory of Open Access Journals (Sweden)

    İlgen Ertam

    2014-03-01

    Full Text Available Intense Pulsed Light (IPL; is a light system of 500-1200 nm wavelength which is used for the treatment of hair removal, hyperpigmentation, non-ablative skin resurfacing and superficial vascular lesions. The mechanism of action is thought to be the focal epidermal coagulation due to selective photothermolysis in the epidermal keratinocytes and melanocytes. A variety of laser systems can be used in the treatment of lsolar entigo. The aim of this study is to investigate the effectiveness of IPL in solar lentigo. Materials and Methods: The archives of Cosmetology Unit retrospectively reviewed for the patients with the diagnosis of solar lentigo from March 2007 to November 2010. There were 139 files of patients who were diagnosed as solar lentigo clinically and dermoscopically and treated by IPL (L900 a & m IPL. Informed consent was taken from all patients. Among them, 42 patients who had come to controls regularly and had photographed before and after treatment included into the study. Results: A total of 52 lesions of 42 female and 1 male patient included into the study. Patients’ mean age was 42±9.6 years, ranging between 33 to 88. Of the lesions, 27 lesions(51.9% were on cheek, 7 lesions (13.5% were on zygoma, 6 lesions (11.5% were on chin, 4 lesions (7.7% were on hands, 4 lesions (7.7% were on forehead, 2 lesions(3.8% were on nose, 2 lesions (3.8% were on forearm. The mean number of sessions was 3.28 ranging between 1 and 7. After treatment, improvement was over 75% in 57,7% lesions, 50-75% in 17.3% of the lesions, 25-50% in 17.3% of the lesions, under 25% in 7.7% of the lesions. Conclusion: According to the results of our work, IPL can be accepted as an effective, cheap and safety method in terms of its side effects in treatment of solar lentigo.

  2. The impact of left ventricular preload reduction on cardiac pulsed doppler indices during hemodialysis and its relation to intra-dialysis hypotension: A pulsed doppler study

    Directory of Open Access Journals (Sweden)

    Alarrayed Sameer

    2009-01-01

    Full Text Available Fluid status in the body plays an important role on left ventricular (LV filling in patients with end-stage renal disease (ESRD on regular hemodialysis (HD, and plays a role in intra-dialysis hemo-dynamic derangement. Fifty-two patients with ESRD on regular HD, including 34 males with a mean age of 45.5 ± 13 years (range 18-72 years, were studied. All patients underwent Echo-pulsed Doppler study before and immediately after a HD session. The Echo Doppler indices noted were: LV cavity dimension and wall thickness, LV ejection fraction (LVEF%, trans-mitral early diastolic filling velocity (E wave, atrial filling diastolic velocity (A wave, E/A ratio, Deceleration Time (DT of E wave, Isovolumic relaxation time (IVRT, Aortic Velocity Integral (AVI and Inferior Vena Cava Diameter (VCD at expiration. Patients were divided into two groups according to the amount of net ultra filtrate loss after HD. Group I comprised of 25 patients with fluid loss of < 2 liters, and Group II had 27 patients with fluid loss > 2 liters. During the HD session, each patient was observed for the development of acute clinical events such as arterial hypotension (systolic BP less than 90 mmHg, chest pain and arrhythmias. There was a significant difference between the two groups in the mean values, pre- and post- HD, of reduction of E wave velocity (p< 0.01, the reduction of E/A ratio (p< 0.05, the increment in DT of E wave (p< 0.05, the reduction in AVI (p< 0.01 and the reduction of VCD (p< 0.05. There was no significant difference between the groups in the reduction of A wave velocity and the reduction of IVRT. Among the study patients, 11 (21% developed systolic hypo-tension during HD. The pre-dialysis mean values of E/A ratio and DT of E wave in patients who developed hypotension compared to those who did not was 0.7 ± 0.2 vs 1.1 ± 0.2.1 (p< 0.001 and 246 ± 40 vs 224 ± 34 msec (p< 0.05, respectively. Our study suggests that preload reduction in patients with ESRD on

  3. The Study of State-Selected Ion-Molecule Reactions using the Vacuum Ultraviolet Pulsed Field Ionization-Photoion Technique

    Science.gov (United States)

    2006-01-01

    challenges of improving the kinetic energy resolu- Very recently, high-level time-dependent quantum mechani - tion in ion-molecule collisional experiments...2006) Copyright 2006 American Institute of Physics 14. ABSTRACT This paper presents the methodology to generate beams of ions in single quantum states...in single quantum states for bimolecular ion-molecule reaction dynamics studies using pulsed field ionization (PFI) of atoms or molecules in high-n

  4. Radiation-Induced Chemical Reactions in Hydrogel of Hydroxypropyl Cellulose (HPC): A Pulse Radiolysis Study.

    Science.gov (United States)

    Yamashita, Shinichi; Ma, Jun; Marignier, Jean-Louis; Hiroki, Akihiro; Taguchi, Mitsumasa; Mostafavi, Mehran; Katsumura, Yosuke

    2016-12-01

    We performed studies on pulse radiolysis of highly transparent and shape-stable hydrogels of hydroxypropyl cellulose (HPC) that were prepared using a radiation-crosslinking technique. Several fundamental aspects of radiation-induced chemical reactions in the hydrogels were investigated. With radiation doses less than 1 kGy, degradation of the HPC matrix was not observed. The rate constants of the HPC composing the matrix, with two water decomposition radicals [hydroxyl radical ((•)OH) and hydrated electron ([Formula: see text])] in the gels, were determined to be 4.5 × 10(9) and 1.8 × 10(7) M(-1) s(-1), respectively. Direct ionization of HPC in the matrix slightly increased the initial yield of [Formula: see text], but the additionally produced amount of [Formula: see text] disappeared immediately within 200 ps, indicating fast recombination of [Formula: see text] with hole radicals on HPC or on surrounding hydration water molecules. Reactions of [Formula: see text] with nitrous oxide (N2O) and nitromethane (CH3NO2) were also examined. Decay of [Formula: see text] due to scavenging by N2O and CH3NO2 were both slower in hydrogels than in aqueous solutions, showing slower diffusions of the reactants in the gel matrix. The degree of decrease in the decay rate was more effective for N2O than for CH3NO2, revealing lower solubility of N2O in gel than in water. It is known that in viscous solvents, such as ethylene glycol, CH3NO2 exhibits a transient effect, which is a fast reaction over the contact distance of reactants and occurs without diffusions of reactants. However, such an effect was not observed in the hydrogel used in the current study. In addition, the initial yield of [Formula: see text], which is affected by the amount of the scavenged precursor of [Formula: see text], in hydrogel containing N2O was slightly higher than that in water containing N2O, and the same tendency was found for CH3NO2.

  5. Spin-dependent transport and recombination in solar cells studied by pulsed electrically detected magnetic resonance

    Energy Technology Data Exchange (ETDEWEB)

    Behrends, Jan

    2009-11-11

    This thesis deals with spin-dependent transport and recombination of charge carriers in solar cells. A systematic study on the influence of localized paramagnetic states which act as trapping and recombination centres for photogenerated charge carriers, is presented for three different types of solar cells. The central technique used in this thesis is electrically detected magnetic resonance (EDMR). The capabilities of pulsed (p) EDMR were extended with regard to the detection sensitivity. These improvements allowed pEDMR measurements on fully processed devices from cryogenic to room temperature. The instrumental upgrades also set the stage for pEDMR measurements at different resonance frequencies. In high-efficiency solar cells based on the heterojunction between hydrogenated amorphous silicon (a-Si:H) and crystalline silicon (c-Si), recombination via performancelimiting interface states could directly be measured electrically for the first time. The identification of these defects could be achieved by exploiting their orientation with regard to the surface. In thin-film solar cells based on hydrogenated microcrystalline silicon ({mu}-Si:H) the situation is more complex due to the heterogeneous and disordered structure of the material itself. In addition, these cells are multilayer-systems comprising three different silicon layers with different doping levels and microstructures. By combining a systematic alteration of the sample structure with the information extracted from deconvoluting spectrally overlapping signals in the time domain, it was possible to assign the spin-dependent signals to defects in the individual layers of the solar cells. Benefiting from the instrumental improvements, recombination via dangling bond states in silicon-based solar cells could be investigated by pEDMR at room temperature for the first time. In organic bulk heterojunction solar cells based on MEH-PPV and PCBM two different spin-dependent mechanisms coexist. Both processes

  6. A comparative study of the ionic keV X-ray line emission from plasma produced by the femtosecond, picosecond and nanosecond duration laser pulses

    Indian Academy of Sciences (India)

    V Arora; P A Naik; B S Rao; P D Gupta

    2012-02-01

    We report here an experimental study of the ionic keV X-ray line emission from magnesium plasma produced by laser pulses of three widely different pulse durations (FWHM) of 45 fs, 25 ps and 3 ns, at a constant laser fluence of ∼ 1.5 × 104 J cm-2. It is observed that the X-ray yield of the resonance lines from the higher ionization states such as H- and He-like ions decreases on decreasing the laser pulse duration, even though the peak laser intensities of 3.5 × 1017 W cm-2 for the 45 fs pulses and 6.2 × 1014 W cm-2 for the 25 ps pulses are much higher than 5 × 1012 W cm-2 for the 3 ns laser pulse. The results were explained in terms of the ionization equilibrium time for different ionization states in the heated plasma. The study can be useful to make optimum choice of the laser pulse duration to produce short pulse intense X-ray line emission from the plasma and to get the knowledge of the degree of ionization in the plasma.

  7. Study on a 10 W/90 K in-line pulse tube cryocooler

    Science.gov (United States)

    Zhang, Ankuo; Chen, Xi; Wu, Yi Nong; Zhang, Hua; Yang, Kaixiang

    2012-12-01

    A Stirling-type in-line pulse tube cryocooler (PTC) has been designed, built and tested at Shanghai Institute of Technical Physics (SITP), Chinese Academy of Sciences. This PTC prototype can obtain a low-noise cooling capacity of more than 10 W at around 90 K cold head temperature and is used for cooling a space-borne infrared photo detector. In order to achieve a highly efficient PTC, a simplified numerical simulation model has been established for design and optimization. The simulation results of the regenerator, pulse tube and inertance tube are analyzed in detail. Besides, some key parameters of the PTC are listed in the paper. The PTC's performances are tested at different operating frequencies from 42 Hz to 55 Hz and its reject temperature dependence is observed in the range of 290 K to 320 K. Furthermore, the map of the PTC's performance characteristics is presented.

  8. Study on the method of polarization suppression of cheating jamming in pulse Doppler radar

    Institute of Scientific and Technical Information of China (English)

    Song Lizhong; Qiao Xiaolin; Meng Xiande; Jin Ming

    2005-01-01

    A jamming suppression method based on polarization signal detection is proposed under common range and velocity cheating jammingfor pulse Doppler radar. On the basis of the separation of the target and the jamming, the range and velocity track on the true target are realized. Firstly the signal processing model of the full polarization pulse Doppler radar is introduced. Secondly the method of correct target separation is discussed, which is the twice detections of energy and polarization state on the two dimension resolution cells of range and velocity of the radar echo. Finally the simulations are performed and the results prove the validity. What' s more, multiple range and velocity cheating jamming can be suppressed at the same time if the target and the jamming are different in the polarization domain.

  9. Mechanical Studies on Treatment of Malignant Tumour by Ultralow Frequency Pulsed- Gradient Magnetic Fields

    Institute of Scientific and Technical Information of China (English)

    Deng Ren-qing; Liu Qing-hua; Zhang Hu-sheng

    2003-01-01

    Ultralow frequency (ULF) pulsed-gradient magnetic field (with the maximum intensity of 0. 6-2. 0 T,gradient of 10-100 T @ m-1 , pulse width of 20-200 ms and frequency of 0. 16-1. 34 Hz) treatment of mice can inhibit murine malignant tumour growth and can induce apoptosis of cancer cell. The apoptotic cancer cell contracted, became rounder and divorced from adjacent cells; the heterochromatin condensed and coagulated together along the inner side of the nuclear membrane; the endoplasmic reticulums expanded and fused with the cellular membrane; many apoptotic bodies which were packed by the cellular membrane appeared and were devoured by some lymphocytes and plasma. By Lorentz force the magnetic field keeps the moving ions within bounds of Larmor radius. Thus, penetrating capability of the positive and negative ions through the cell membrane was affected,even the role on the cell membrane formed.

  10. Assessment of the therapeutic benefit of dexamethasone cyclophosphamide pulse versus only oral cyclophosphamide in phase II of the dexamethasone cyclophosphamide pulse therapy: A preliminary prospective randomized controlled study

    Directory of Open Access Journals (Sweden)

    Nisha V Parmar

    2013-01-01

    Full Text Available Background: Dexamethasone cyclophosphamide pulse (DCP therapy is an established mode of treatment for pemphigus in India. Aims: To assess the therapeutic benefit of additional DCPs (phase II, consolidation phase versus immediate oral cyclophosphamide, usually used in phase III (maintenance phase, after initial DCP therapy (phase I and to assess which laboratory test (DIF or ELISA will reflect the clinical relapse best. Methods: Nineteen newly recruited patients of pemphigus vulgaris (PV received monthly DCPs in phase I and were then randomized into two groups. Group A (10 patients received monthly DCPs for nine months and Group B (nine patients received only oral cyclophosphamide for nine months. Direct immunofluorescence (DIF and enzyme-linked immunosorbent assay (ELISA were tested before starting DCP regimen, and at 0,3,6,9 months after randomization. Results: Clinical relapse by the end of follow-up period occurred in only one patient in each group. In these cases, DIF became (again positive before the relapse. No statistically significant difference between the two groups was found at three, six and nine months by ELISA indices and DIF grading. Conclusion: Although the DCP regimen is the standard therapy for pemphigus in India, we found no difference in the clinical outcome between patients receiving nine DCPs in phase II and patients shifted directly from phase I to III. Periodic testing using DIF and Dsg ELISA were found to be useful to monitor disease activity and predict a relapse. Further large scale studies are required to assess if patients can be shifted directly from phase I to III and maintained only on oral cyclophosphamide.

  11. Pulsed electrically detected magnetic resonance study of spin relaxation and recombination in thin-film silicon solar cells

    Energy Technology Data Exchange (ETDEWEB)

    Fehr, Matthias; Behrends, Jan; Schnegg, Alexander; Lips, Klaus; Rech, Bernd [Helmholtz-Zentrum Berlin, Silizium Photovoltaik, Berlin (Germany); Astakhov, Oleksander; Finger, Friedhelm [Forschungszentrum Juelich (Germany). IEF-5 Photovoltaik

    2009-07-01

    We have investigated the influence of paramagnetic states on electronic transport processes in thin-film pin solar cells with pulsed Electrically Detected Magnetic Resonance (pEDMR) at X-Band frequency and low temperature (10 K). The solar cells consist of an intrinsic microcrystalline absorber layer and amorphous or microcrystalline n/p contacting layers. In addition to the identification of the participating paramagnetic centres by their g-factors, pEDMR can be used to study the dynamics of the electronic processes in detail. We present measurements of modified EPR pulse sequences in order to identify the dominating relaxation mechanisms within correlated solid-state spin-pairs. By this technique a monitoring of the spin and charge motion is possible. In the outlook we present measurements of the electron spin echo envelope and critically discuss modulations in terms of dipolar coupling within the spin-pairs or hyperfine couplings to surrounding nuclei.

  12. Basic study on pulse-intensity-domain depth-controlled photodynamic therapy for transurethral prostate cancer

    Science.gov (United States)

    Ohmori, Sayaka; Masuda, Kensuke; Yamakawa, Yuko; Arai, Tsunenori

    2006-02-01

    Photodynamic therapy (PDT) is promising modality for cancer. Prostate cancer is the most common cancer in USA. We proposed transurethral prostate cancer treatment using the pulse-intensity-domain depth-controlled PDT to preserve urethra wall. We have found that photocytotoxicity has been suppressed under high-intensity pulsed excitation with the second generation photosensitizers. We aim to apply this effect to form intact portion on the surface of the irradiated field. Irradiation condition dependence of photocytotoxicity of rat prostate cancer cell line R3327-AT-1 was investigated with two clinical photosensitizers, Porfimer sodium and Talaporfin sodium. A pulsed laser was irradiated with the power energy density ranging from 1.25 to 10 mJ/cm2. Near-infrared luminescence from singlet oxygen in the solution of those two photosensitizers was measured transiently. We performed PDT against a rat subcutaneous prostate tumor mode with Talaporfin sodium (2mg/kg) injected intravenously 1 h prior to the irradiation. The laser was irradiated with the power energy density 2.5 or 10 mW/cm2, with the total fluence of 50 J/cm2. Photocytotoxicity in vitro and the singlet oxygen generation were both suppressed with the 10mJ/cm2 irradiation with Talaporfin sodium, while these with Porfimer sodium were kept relatively constant. The surface of the irradiated field of 1mm in thickness remained intact, while the tumor damaged layer of 1.3 mm in thickness was obtained in the case of 10mJ/cm2 irradiation. We think Talaporfin sodium has high sensitivity to the pulse energy density, which might be useful to realize urethra preserved PDT for prostate cancer.

  13. Solid-state pulse forming module with adjustable pulse duration

    Science.gov (United States)

    Wang, Langning; Liu, Jinliang; Qiu, Yongfeng; Chu, Xu; Zhang, Qingmeng

    2017-03-01

    A new solid-state pulse forming module is described in this paper. The pulse forming module is fabricated on a glass ceramic substrate, with the dimension of 250 mm × 95 mm × 4 mm. By changing the copper strips used in the pulse forming modules, the pulse duration of the obtained pulsed can range from 80 ns to 140 ns. Both the simulation and tests show that the pulse forming module has a good pulse forming ability. Under a high voltage in microsecond's time, the new pulse forming modules can hold off a voltage up to 25 kV higher than that of the previous study. In addition, future optimization for the field enhancement near the thin electrode edge has been proposed and simulated.

  14. Study on the mode-transition of nanosecond-pulsed dielectric barrier discharge between uniform and filamentary by controlling pressures and pulse repetition frequencies

    Science.gov (United States)

    Yu, Sizhe; Lu, Xinpei

    2016-09-01

    We investigate the temporally resolved evolution of the nanosecond pulsed dielectric barrier discharge (DBD) in a moderate 6mm gap under various pressures and pulse repetition frequencies (PRFs) by intensified charge-coupled device (ICCD) images, using synthetic air and its components oxygen and nitrogen. It is found that the pressures are very different when the DBD mode transits between uniform and filamentary in air, oxygen, and nitrogen. The PRFs can also obviously affect the mode-transition. The transition mechanism in the pulsed DBD is not Townsend-to-streamer, which is dominant in the traditional alternating-voltage DBDs. The pulsed DBD in a uniform mode develops in the form of plane ionization wave, due to overlap of primary avalanches, while the increase in pressure disturbs the overlap and DBD develops in streamer instead, corresponding to the filamentary mode. Increasing the initiatory electron density by pre-ionization methods may contribute to discharge uniformity at higher pressures. We also find that the dependence of uniformity upon PRF is non-monotonic.

  15. Study on the mode-transition of nanosecond-pulsed dielectric barrier discharge between uniform and filamentary by controlling pressures and pulse repetition frequencies

    Science.gov (United States)

    Yu, S.; Pei, X.; Hasnain, Q.; Nie, L.; Lu, X.

    2016-02-01

    In this paper, we investigate the temporally resolved evolution of the nanosecond pulsed dielectric barrier discharge (DBD) in a moderate 6 mm discharge gap under various pressures and pulse repetition frequencies (PRFs) by intensified charge-coupled device (ICCD) images, using dry air and its components oxygen and nitrogen. It is found that the pressures are very different when the mode transits between uniform and filamentary in air, oxygen, and nitrogen. The PRFs can also obviously affect the mode-transition. The transition mechanism in the pulsed DBD is not Townsend-to-Streamer, which is dominant in the traditional alternating-voltage DBD. The pulsed DBD in a uniform mode develops in the form of plane ionization wave due to overlap of primary avalanches, while the increase in pressure disturbs the overlap and discharge develops in streamer, corresponding to the filamentary mode. Increasing the initial electron density by pre-ionization may contribute to discharge uniformity at higher pressures. We also found that the dependence of homogeneity upon PRF is a non-monotonic one.

  16. An experimental study of high power microwave pulsed discharge in nitrogen

    Energy Technology Data Exchange (ETDEWEB)

    Mesko, M; Bonaventura, Z; Vasina, P; Kudrle, V; Talsky, A; Trunec, D; Frgala, Z; Janca, J [Department of Physical Electronics, Masaryk University, Kotlarska 2, CZ-61137 Brno (Czech Republic)

    2006-08-01

    We investigated a plasma excited by high power pulsed microwaves (MWs) (pulse duration 2.5 {mu}s, repetition rate 400 Hz, peak power 10{sup 5} W, frequency 9.4 GHz) in nitrogen at reduced pressure (pressure range 10-2000 Pa) with the aim of a better understanding of such types of discharge. The construction of the experimental device suppresses the plasma-wall interactions and therefore the volume processes are predominant. To obtain the temporal evolution of the electron density we used two MW interferometers at frequencies of 15 and 35 GHz with dielectric rod waveguides which gives them the capability of localized measurements. We estimated the effective collision frequency from the absorption of a measurement beam. Time resolved optical emission spectroscopy of the 1st negative system and the 2nd positive system was carried out, too. Due to a high power input the discharge dynamics was fast and the steady state was typically reached in 1 {mu}s. We found that the effective collision frequency has the same temporal behaviour as the 2nd positive system of N{sub 2}, including a characteristic maximum at the beginning of the pulse.

  17. Langmuir probe study of a titanium pulsed filtered cathodic arc discharge

    Energy Technology Data Exchange (ETDEWEB)

    Andruczyk, D [School of Physics, University of Sydney, NSW 2006 (Australia); Tarrant, R N [School of Physics, University of Sydney, NSW 2006 (Australia); James, B W [School of Physics, University of Sydney, NSW 2006 (Australia); Bilek, M M M [School of Physics, University of Sydney, NSW 2006 (Australia); Warr, G B [School of Physics, University of Sydney, NSW 2006 (Australia)

    2006-08-01

    A Langmuir probe has been used to make measurements of plasma parameters as a function of time at the substrate position in a magnetically-filtered pulsed cathodic arc discharge. Electron density, n{sub e}, and effective electron temperature, T{sub eff}, were calculated as a function of time from the I-V curves. The Druyvesteyn method was used to determine the electron energy distribution. Ion density was calculated using the assumption of plasma quasi-neutrality and an average ion charge state. Results show that over the plateau region (350-600 {mu}s) of the pulse, the electron energy distribution is Maxwellian with T{sub eff} = T{sub e} = (10 {+-} 1) eV. During the rise and fall times of the pulse, the electron energy distribution is non-Maxwellian with an effective temperature of up to 15 to 20 eV during the rise time and {approx}7 eV during the fall time. The electron density during the plateau is n{sub e} = (3.0-6.0 {+-} 0.5) x 10{sup 17} m{sup -3}.

  18. Study on Ultra-Short Laser Pulse Ablation of Metals by Molecular Dynamics Simulation

    Institute of Scientific and Technical Information of China (English)

    LIU Xuan; WANG Yang; ZHAO Li-jie

    2006-01-01

    The dynamical progresses involved in ultra-short laser pulse ablation of face-centered cubic metals under stress confinement condition are described completely using molecular dynamics method. The laser beam absorption and thermal energy turning into kinetics energy of atoms are taken into account to give a detailed picture of laser metal interaction. Superheating phenomenon is observed, and the phase change from solid to liquid is characterized by a destroyed atom configuration and a decreased number density. The steep velocity gradients are found in the systems of Cu and Ni after pulse in consequence of located heating and exponential decrease of fluences following the Lambert-Beer expression. The shock wave velocities are predicted to be about 5000m/s in Cu and 7200m/s in Ni. The higher ablation rates are obtained from simulations compared with experimental data as a result of a well-defined crystalline surface irradiated by a single pulse. Simulation results show that the main mechanisms of ablation are evaporation and thermoelastic stress due to located heating.

  19. Adapting Particle-In-Cell simulations to the study of short pulse laser damage

    Science.gov (United States)

    Mitchell, Robert; Schumacher, Douglass; Chowdhury, Enam

    2014-10-01

    We present novel Particle-In-Cell (PIC) simulations of the full femtosecond-pulse laser damage process and the resulting damage spot morphology. At the heart of these simulations is the implementation, for the first time, of a Lennard-Jones pair potential model (LJPPM) for PIC codes. The use of PIC facilitates the first ab-initio treatment of realistic target sizes, retaining the strengths of PIC including self-consistent treatment of the laser-particle interaction and subsequent generation of plasma waves and electron heating, while the LJPPM allows a PIC code to treat a system of particles as a medium which can ablate, melt, and resolidify. Combining these two approaches, we model the effect of a femtosecond-pulse laser on metal targets near and above the damage threshold and compare to recent experimental results. In particular, we present the first simulations of the emergence of Laser-Induced Periodic Surface Structure (LIPSS) upon femtosecond-pulse laser irradiation.

  20. Bifurcation physics of magnetic islands and stochasticity explored by heat pulse propagation studies in toroidal plasmas

    Science.gov (United States)

    Ida, K.; Kobayashi, T.; Yoshinuma, M.; Suzuki, Y.; Narushima, Y.; Evans, T. E.; Ohdachi, S.; Tsuchiya, H.; Inagaki, S.; Itoh, K.

    2016-09-01

    Bifurcation physics of a magnetic island was investigated using the heat pulse propagation technique produced by the modulation of electron cyclotron heating. There are two types of bifurcation phenomena observed in a large helical device (LHD) and DIII-D. One is a bifurcation of the magnetic topology between nested and stochastic fields. The nested state is characterized by the bi-directional (inward and outward) propagation of the heat pulse with slow propagation speed. The stochastic state is characterized by the fast propagation of the heat pulse with electron temperature flattening. The other bifurcation is between the magnetic island with larger thermal diffusivity and that with smaller thermal diffusivity. The damping of toroidal flow is observed at the O-point of the magnetic island both in helical plasmas and in tokamak plasmas during a mode locking phase with strong flow shears at the boundary of the magnetic island. Associated with the stochastization of the magnetic field, the abrupt damping of toroidal flow is observed in LHD. The toroidal flow shear shows a linear decay, while the ion temperature gradient shows an exponential decay. This observation suggests that this flow damping is due to the change in the non-diffusive term of momentum transport.

  1. Gold Nanoparticle-Mediated Delivery of Molecules into Primary Human Gingival Fibroblasts Using ns-Laser Pulses: A Pilot Study

    Directory of Open Access Journals (Sweden)

    Judith Krawinkel

    2016-05-01

    Full Text Available Interaction of gold nanoparticles (AuNPs in the vicinity of cells’ membrane with a pulsed laser (λ = 532 nm, τ = 1 ns leads to perforation of the cell membrane, thereby allowing extracellular molecules to diffuse into the cell. The objective of this study was to develop an experimental setting to deliver molecules into primary human gingival fibroblasts (pHFIB-G by using ns-laser pulses interacting with AuNPs (study group. To compare the parameters required for manipulation of pHFIB-G with those needed for cell lines, a canine pleomorphic adenoma cell line (ZMTH3 was used (control group. Non-laser-treated cells incubated with AuNPs and the delivery molecules served as negative control. Laser irradiation (up to 35 mJ/cm2 resulted in a significant proportion of manipulated fibroblasts (up to 85%, compared to non-irradiated cells: p < 0.05, while cell viability (97% was not reduced significantly. pHFIB-G were perforated as efficiently as ZMTH3. No significant decrease of metabolic cell activity was observed up to 72 h after laser treatment. The fibroblasts took up dextrans with molecular weights up to 500 kDa. Interaction of AuNPs and a pulsed laser beam yields a spatially selective technique for manipulation of even primary cells such as pHFIB-G in high throughput.

  2. A systematic study of the impact of freshwater pulses with respect to different geographical locations

    Energy Technology Data Exchange (ETDEWEB)

    Roche, Didier M.; Renssen, Hans [Vrije Universiteit Amsterdam, Section Climate Change and Landscape Dynamics, Department of Earth Sciences, Amsterdam (Netherlands); Wiersma, Ane P. [Deltares, Subsurface and Groundwater systems, Utrecht (Netherlands)

    2010-06-15

    The first comparative and systematic climate model study of the sensitivity of the climate response under Last Glacial Maximum (LGM) conditions to freshwater perturbations at various locations that are known to have received significant amounts of freshwater during the LGM (21 kyr BP) climate conditions is presented. A series of ten regions representative of those receiving most of the meltwater from decaying ice-sheets during the deglaciation is defined, comprising the border of LGM ice-sheets, outlets of rivers draining part of the melting ice-sheets and iceberg melt zones. The effect of several given freshwater fluxes applied separately in each of these regions on regional and global climate is subsequently tested. The climate response is then analysed both for the atmosphere and oceans. Amongst the regions defined, it is found that the area close by and dynamically upstream to the main deep water formation zone in the North Atlantic are most sensitive to freshwater pulses, as is expected. However, some important differences between Arctic freshwater forcing and Nordic Seas forcing are found, the former having a longer term response linked to sea-ice formation and advection whereas the latter exhibits more direct influence of direct freshening of the deep water formation sites. Combining the common surface temperature response for each respective zone, we fingerprint the particular surface temperature response obtained by adding freshwater in a particular location. This is done to examine if a surface climate response can be used to determine the origin of a meltwater flux, which is relevant for the interpretation of proxy data. We show that it is indeed possible to generally classify the fingerprints by their origin in terms of sea-ice modification and modification of deep-water formation. Whilst the latter is not an unambiguous characterization of each zone, it nonetheless provides important clues on the physical mechanisms at work. In particular, it is shown

  3. Pulse wave velocity is associated with muscle mass decline: Health ABC study.

    Science.gov (United States)

    Abbatecola, Angela Marie; Chiodini, Paolo; Gallo, Ciro; Lakatta, Edward; Sutton-Tyrrell, Kim; Tylavsky, Frances A; Goodpaster, Bret; de Rekeneire, Natalie; Schwartz, Ann V; Paolisso, Giuseppe; Harris, Tamara

    2012-04-01

    Age-related mechanisms that lead to sarcopenia are not entirely understood. Basal leg blood flow declines with aging by augmented sympathetic vasoconstriction and arterial stiffening, thus a dysfunction in blood vessel dynamics may have an independent role on sarcopenia. We determined whether pulse wave velocity (PWV), marker of arterial stiffness, was associated with skeletal muscle decline. Observational cohort study of older adults(70-79 years) living in Pittsburgh, PA, USA or Memphis, TN, USA. Analyses included 2,405 participants. Correlations among muscle parameters including skeletal muscle density and intermuscular adipose tissue using mid-thigh CT scans were assessed. Linear mixed models tested the association between the change in the sarcopenic index (SI) (assessed by dual energy X-ray absorptiometry) over time and baseline PWV independently of multiple confounders. SI was defined: appendicular lean mass/squared height and calculated at every follow-up (n = 6). Baseline PWV was significantly higher in black women compared to white women (930 ± 431 vs. 843 ± 366; p = 0.0001), while there were no significant differences between black and white men (943 ± 402 vs. 911 ± 375; p = 0.1786). Baseline analyses showed an independent negative association between PWV and muscle parameters after adjusting for confounders in both genders. The PWV-by-race interaction was significant in women and analyses are reported separately by race. Prospective mixed models showed that PWV was an independent determinant of the SI in all men (β = -0.1043; p = 0.0065) and in white women (β = -0.1091; p = 0.0192). In analyses examining the effect of arterial stiffness on limb lean mass over time, PWV correlated with lower leg (β = -0.2196; p = 0.0002)and arm mass (β = -0.0985; p = 0.0011) in all men and lower leg mass(β = -0.1608; p = 0.0027)in white women. In older persons, arterial stiffening is associated with skeletal muscle mass decline differently for race and

  4. Charge transfer from 2-aminopurine radical cation and radical anion to nucleobases: A pulse radiolysis study

    Energy Technology Data Exchange (ETDEWEB)

    Manoj, P. [School of Chemical Sciences, Mahatma Gandhi University, Kottayam 686 560, Kerala (India); Mohan, H. [Radiation Chemistry and Chemical Dynamics Division, Bhabha Atomic Research Centre, Mumbai 400 085 (India); Mittal, J.P. [Radiation Chemistry and Chemical Dynamics Division, Bhabha Atomic Research Centre, Mumbai 400 085 (India); Manoj, V.M. [School of Chemical Sciences, Mahatma Gandhi University, Kottayam 686 560, Kerala (India); Aravindakumar, C.T. [School of Chemical Sciences, Mahatma Gandhi University, Kottayam 686 560, Kerala (India)], E-mail: CT-Aravindakumar@rocketmail.com

    2007-01-08

    Pulse radiolysis study has been carried out to investigate the properties of the radical cation of 2-aminopurine (2AP) and the probable charge transfer from the radical cation and radical anion of 2AP to natural nucleobases in aqueous medium. The radical cation of 2AP was produced by the reaction of sulfate radical anion (SO{sub 4}{sup dot-}). The time resolved absorption spectra obtained by the reaction of SO{sub 4}{sup dot-} with 2AP at neutral pH have two distinct maxima at 380 and 470nm and is assigned to the formation of a neutral radical of the form 2AP-N{sup 2}(-H){sup dot} (k{sub 2}=4.7x10{sup 9}dm{sup 3}mol{sup -1}s{sup -1} at pH 7). This neutral radical is formed from the deprotonation reaction of a very short-lived radical cation of 2AP. The transient absorption spectra recorded at pH 10.2 have two distinct maxima at 400 and 480nm and is assigned to the formation of a nitrogen centered radical (2AP-N(9){sup dot}). As the hole transport from 2AP to guanine is a highly probable process, the reaction of SO{sub 4}{sup dot-} is carried out in the presence of guanosine, adenosine and inosine. The spectrum obtained in the presence of guanosine was significantly different from that in the absence and it showed prominent absorption maxima at 380 and 470nm, and a weak broad maximum centered around 625nm which match well with the reported spectrum of a neutral guanine radical (G(-H){sup dot}). The electron transfer reaction from the radical anion of 2AP to thymine (T), cytidine (Cyd) and uridine (Urd) was also investigated at neutral pH. Among the three pyrimidines, only the transient spectrum in the presence of T gave a significant difference from the spectral features of the electron adduct of 2AP, which showed a prominent absorption maximum at 340nm and this spectrum is similar to the electron adduct spectrum of T. The preferential reduction of thymine by 2AP{sup dot-} and the oxidation of guanosine by 2AP{sup dot+} clearly follow the oxidation

  5. Preventing Electromagnetic Pulse Irradiation Damage on Testis Using Selenium-rich Cordyceps Fungi. A Preclinical Study in Young Male Mice.

    Science.gov (United States)

    Miao, Xia; Wang, Yafeng; Lang, Haiyang; Lin, Yanyun; Guo, Qiyan; Yang, Mingjuan; Guo, Juan; Zhang, Yanjun; Zhang, Jie; Liu, Junye; Liu, Yaning; Zeng, Lihua; Guo, Guozhen

    2017-02-01

    Networked 21st century society, globalization, and communications technologies are paralleled by the rise of electromagnetic energy intensity in our environments and the growing pressure of the environtome on human biology and health. The latter is the entire complement of environmental factors, including the electromagnetic energy and the technologies that generate them, enacting on the digital citizen in the new century. Electromagnetic pulse (EMP) irradiation might have serious damaging effects not only on electronic equipment but also in the whole organism and reproductive health, through nonthermal effects and oxidative stress. We sought to determine whether EMP exposure (1) induces biological damage on reproductive health and (2) the extent to which selenium-rich Cordyceps fungi (daily coadministration) offer protection on the testicles and spermatozoa. In a preclinical randomized study, 3-week-old male BALB/c mice were repeatedly exposed to EMP (peak intensity 200 kV/m, pulse edge 3.5 ns, pulse width 15 ns, 0.1 Hz, and 400 pulses/day) 5 days per week for four consecutive weeks, with or without coadministration of daily selenium-rich Cordyceps fungi (100 mg/kg). Testicular index and spermatozoa formation were measured at baseline and 1, 7, 14, 28, and 60 day time points after EMP exposure. The group without Cordyceps cotreatment displayed decreased spermatozoa formation, shrunk seminiferous tubule diameters, and diminished antioxidative capacity at 28 and 60 days after exposure (p < 0.05). The Cordyceps daily cotreatment alleviated the testicular damage by EMP exposure, increased spermatozoa formation, and reduced apoptotic spermatogenic cells. These observations warrant further preclinical and clinical studies as an innovative approach for potential protection against electromagnetic radiation in the current age of networked society and digital citizenship.

  6. Bacterial inactivation using pulsed light

    OpenAIRE

    Elmnasser, Noura; Ritz, Magali; Leroi, Francoise; Orange, Nicole; Bakhrouf, Amina; Federighi, Michel

    2007-01-01

    Pulsed light is a new method intended for the decontamination of food surfaces using short, high frequency pulses of an intense broad spectrum. The effects of broad spectrum pulsed light on the survival of Listeria monocytogenes Scott A, Listeria monocytogenes CNL, Pseudomonas fluorescens MF37 and Photobacterium phosphoreum SF680 populations on agar and in a liquid medium were investigated during this study. The sterilisation system generated 1.5 J cm(-2) per pulse with eight lamps for 300 mu...

  7. Kinetic studies of NO formation in pulsed air-like low-pressure dc plasmas

    Science.gov (United States)

    Hübner, M.; Gortschakow, S.; Guaitella, O.; Marinov, D.; Rousseau, A.; Röpcke, J.; Loffhagen, D.

    2016-06-01

    The kinetics of the formation of NO in pulsed air-like dc plasmas at a pressure of 1.33 mbar and mean currents between 50 and 150 mA of discharge pulses with 5 ms duration has been investigated both experimentally and by self-consistent numerical modelling. Using time-resolved quantum cascade laser absorption spectroscopy, the densities of NO, NO2 and N2O have been measured in synthetic air as well as in air with 0.8% of NO2 and N2O, respectively. The temporal evolution of the NO density shows four distinct phases during the plasma pulse and the early afterglow in the three gas mixtures that were used. In particular, a steep density increase during the ignition phase and after termination of the discharge current pulse has been detected. The NO concentration has been found to reach a constant value of 0.57× {{10}14}~\\text{molecules}~\\text{c}{{\\text{m}}-3} , 1.05× {{10}14}~\\text{molecules}~\\text{c}{{\\text{m}}-3} , and 1.3× {{10}14}~\\text{molecules}~\\text{c}{{\\text{m}}-3} for mean plasma currents of 50 mA, 100 mA and 150 mA, respectively, in the afterglow. The measured densities of NO2 and N2O in the respective mixture decrease exponentially during the plasma pulse and remain almost constant in the afterglow, especially where the admixture of NO2 has a remarkable impact on the NO production during the ignition. The numerical results of the coupled solution of a set of rate equations for the various heavy particles and the time-dependent Boltzmann equation of the electrons agree quite well with the experimental findings for the different air-like plasmas. The main reaction processes have been analysed on the basis of the model calculations and the remaining differences between the experiment and modelling especially during the afterglow are discussed.

  8. Competition reactions of H2O•+ radical in concentrated Cl- aqueous solutions: picosecond pulse radiolysis study.

    Science.gov (United States)

    El Omar, Abdel Karim; Schmidhammer, Uli; Rousseau, Bernard; LaVerne, Jay; Mostafavi, Mehran

    2012-11-29

    Picosecond pulse-probe radiolysis measurements of highly concentrated Cl(-) aqueous solutions are used to probe the oxidation mechanism of the Cl(-). The transient absorption spectra are measured from 340 to 710 nm in the picosecond range for the ultrafast electron pulse radiolysis of halide solutions at different concentrations up to 8 M. The amount of Cl(2)(•-) formation within the electron pulse increases notably with increasing Cl(-) concentration. Kinetic measurements reveal that the direct ionization of Cl(-) cannot solely explain the significant amount of fast Cl(2)(•-) formation within the electron pulse. The results suggest that Cl(-) reacts with the precursor of the OH(•) radical, i.e., H(2)O(•+) radical, to form Cl(•) atom within the electron pulse and the Cl(•) atom reacts subsequently with Cl(-) to form Cl(2)(•-) on very short time scales. The proton transfer reaction between H(2)O(•+) and the water molecule competes with the electron transfer reaction between Cl(-) and H(2)O(•+). Molecular dynamics simulations show that number of water molecules in close proximity decreases with increasing concentration of the salt (NaCl), confirming that for highly concentrated solutions the proton transfer reaction between H(2)O(•+) and a water molecule becomes less efficient. Diffusion-kinetic simulations of spur reactions including the direct ionization of Cl(-) and hole scavenging by Cl(-) show that up to 30% of the H(2)O(•+) produced by the irradiation could be scavenged for solutions containing 5.5 M Cl(-). This process decreases the yield of OH(•) radical in solution on the picosecond time scale. The experimental results for the same concentration of Cl(-) at a given absorbed dose show that the radiation energy absorbed by counterions is transferred to Cl(-) or water molecules and the effect of the countercation such as Li(+), K(+), Na(+), and Mg(2+) on the oxidation yield of Cl(-) is negligible.

  9. A comparative study of continuous versus pulsed radiofrequency discectomy for management of low backache: Prospective randomized, double-blind study

    Science.gov (United States)

    Jena, Bhagya Ranjan; Paswan, Anil; Singh, Yashpal; Loha, Sandeep; Singh, Anil Prasad; Rastogi, Virendra

    2016-01-01

    Background: Radiofrequency (RF) is a minimally invasive target-selective technique that has been used with success for many years in the treatment of different pathologies, such as low back pain, trigeminal neuralgia, and others. Aim: The aim of this study is to compare different mode of RF - continuous RF (CRF) versus pulsed RF (PRF) along with steroid in the management of low back pain of discogenic origin. Setting and Design: Prospective, randomized, double-blind trial. Materials and Methods: Forty patients with chronic discogenic low back pain were randomized to receive CRF plus intradiscal triamcinolone 40 mg (Group 1) or to receive PRF plus intradiscal triamcinolone 40 mg (Group 2). Outcome measured includes immediate as well as long-term pain relief using visual analog scale, the Oswestry Disability Index and straight leg raising test. Statistical Analysis: The continuous variables were compared by one-way analysis of variance test. Discrete variables were compared by Fisher's exact test/Chi-square test/Student's t-test, whichever appropriate. The value of P PRF was insignificant. Conclusion: CRF with steroid seems to be better for treatment of chronic discogenic low back pain than PRF with steroid. PMID:27746559

  10. Use of ns and fs pulse excitation in laser-induced breakdown spectroscopy to improve its analytical performances: A case study on quaternary bronze alloys

    Energy Technology Data Exchange (ETDEWEB)

    Almaviva, Salvatore [ENEA, UTAPRAD, V. E. Fermi 45, 00044 Frascati (Italy); Fantoni, Roberta, E-mail: roberta.fantoni@enea.it [ENEA, UTAPRAD, V. E. Fermi 45, 00044 Frascati (Italy); Caneve, Luisa; Colao, Francesco [ENEA, UTAPRAD, V. E. Fermi 45, 00044 Frascati (Italy); Fornarini, Lucilla [ENEA,UTTAMB, SP Anguillarese 301, Roma (Italy); Santagata, Antonio [CNR-IMIP, UOS Potenza, Zona Industriale, 85050 Tito Scalo (PZ) (Italy); Teghil, Roberto [Università degli Studi della Basilicata, Dipartimento di Scienze, Via dell' Ateneo Lucano 10, 85100 Potenza (Italy)

    2014-09-01

    Analytical performances of Laser Induced Breakdown Spectroscopy (LIBS) resulted not fully satisfactory in some cases such as historical bronzes, therefore, efforts should be focussed on improving ablation efficiency and on better understanding the plasma parameter evolution. To this aim a set of double pulse experiments have been carried out in almost collinear geometry at about 530 nm laser excitation. The first emitting source was either a ns or a fs laser the second a ns one. Data were collected as a function of the interpulse delay, in order to determine the ablation efficiency increase, to study the kinetics of plasma parameters (temperature, electron density) and the decay of atomic and ionic intensities with respect to the optical background. In parallel a previously developed model for laser ablation, ionization and following plasma decay, was implemented, adding a second laser pulse, to analyse the double pulse excitation in the considered geometry, and the time evolution of the same variables was investigated. Model results are able to reproduce the observed experimental trends and support the possibility of improving analytical performances by using the double pulse technique with inter-pulse delays in the entire investigated range. - Highlights: • The Double Pulse LIBS technique is applied to a quaternary metal alloy sample. • Two different Double Pulse LIBS configurations are investigated. • Signal enhancement was experimentally verified in the Double Pulse technique. • Comparison of the experimental results with the proposed theoretical model • Dependence of the LIBS signal by some experimental parameters.

  11. Theoretical study of electronic damage in single particle imaging experiments at XFELs for pulse durations 0.1 - 10 fs

    CERN Document Server

    Gorobtsov, O Yu; Kabachnik, N M; Vartanyants, I A

    2015-01-01

    X-ray free-electron lasers (XFELs) may allow to employ the single particle imaging (SPI) method to determine the structure of macromolecules that do not form stable crystals. Ultrashort pulses of 10 fs and less allow to outrun complete disintegration by Coulomb explosion and minimize radiation damage due to nuclear motion, but electronic damage is still present. The major contribution to the electronic damage comes from the plasma generated in the sample that is strongly dependent on the amount of Auger ionization. Since the Auger process has a characteristic time scale on the order of femtoseconds, one may expect that its contribution will be significantly reduced for attosecond pulses. Here, we study the effect of electronic damage on the SPI at pulse durations from 0.1 fs to 10 fs and in a large range of XFEL fluences to determine optimal conditions for imaging of biological samples. We analyzed the contribution of different electronic excitation processes and found that at fluences higher than $10^{13}$-$...

  12. Performance study of highly efficient 520 W average power long pulse ceramic Nd:YAG rod laser

    Science.gov (United States)

    Choubey, Ambar; Vishwakarma, S. C.; Ali, Sabir; Jain, R. K.; Upadhyaya, B. N.; Oak, S. M.

    2013-10-01

    We report the performance study of a 2% atomic doped ceramic Nd:YAG rod for long pulse laser operation in the millisecond regime with pulse duration in the range of 0.5-20 ms. A maximum average output power of 520 W with 180 J maximum pulse energy has been achieved with a slope efficiency of 5.4% using a dual rod configuration, which is the highest for typical lamp pumped ceramic Nd:YAG lasers. The laser output characteristics of the ceramic Nd:YAG rod were revealed to be nearly equivalent or superior to those of high-quality single crystal Nd:YAG rod. The laser pump chamber and resonator were designed and optimized to achieve a high efficiency and good beam quality with a beam parameter product of 16 mm mrad (M2˜47). The laser output beam was efficiently coupled through a 400 μm core diameter optical fiber with 90% overall transmission efficiency. This ceramic Nd:YAG laser will be useful for various material processing applications in industry.

  13. Effect of yoga on arterial stiffness in elderly subjects with increased pulse pressure: A randomized controlled study.

    Science.gov (United States)

    Patil, Satish Gurunathrao; Aithala, Manjunatha R; Das, Kusal Kanti

    2015-08-01

    We aimed to determine the effect of yoga on arterial function in elderly with increased pulse pressure (PP). Randomized controlled study with two parallel groups. Elderly subjects with PP≥60 mmHg (n=60). Yoga group (n=30) was assigned for yoga training and brisk-walking (BW) group (n=30) for brisk-walk with stretching exercise for 1h in the morning for 6 days in a week for 12 weeks. Arterial stiffness measures: Brachial-ankle pulse wave velocity (baPWV), Carotid-femoral pulse wave velocity (c-f PWV), aortic augmentation index (AIx@75), arterial stiffness index at brachial (bASI) and tibial arteries (aASI). Total serum nitric oxide concentration (NOx) as an index of endothelial function. Heart rate variability (HRV) measures: Low frequency and high frequency in normalized units (LFnu, HFnu) and LF/HF ratio. The mean between-group change (with 95% CI) in arterial stiffness: c-f PWV(m/s) [1.25(0.59-1.89); pyoga group in vascular function, BP and autonomic function, while no significant change within-BW group was observed. Our findings suggest that yoga program offered was more effective than brisk-walk in reducing arterial stiffness along with BP in elderly individuals with increased PP. Yoga can also significantly reduce sympathetic activity and improve endothelial function with enhancement in bioavailability of NO. Copyright © 2015 Elsevier Ltd. All rights reserved.

  14. A broadband radio study of the average profile and giant pulses from PSR B1821-24A

    CERN Document Server

    Bilous, A V; Demorest, P; Ransom, S M

    2014-01-01

    We present the results of wide-band (720-2400 MHz) study of PSR B1821-24A (J1824-2452A, M28A), an energetic millisecond pulsar visible in radio, X-rays and gamma-rays. In radio, the pulsar has a complex average profile which spans >85% of the spin period and exhibits strong evolution with observing frequency. For the first time we measure phase-resolved polarization properties and spectral indices of radio emission throughout almost all of the on-pulse window. We combine this knowledge with the high-energy information to compare M28A to other known gamma-ray millisecond pulsars and to speculate that M28A's radio emission originates in multiple regions within its magnetosphere (i.e. both in the slot or outer gaps near the light cylinder and at lower altitudes above the polar cap). M28A is one of the handful of pulsars which are known to emit Giant Pulses (GPs) -- short, bright radio pulses of unknown nature. We report a drop in the linear polarization of the average profile in both windows of GP generation and...

  15. The accuracy of pulse oximetry in emergency department patients with severe sepsis and septic shock: a retrospective cohort study

    Directory of Open Access Journals (Sweden)

    Lord Jason A

    2010-05-01

    Full Text Available Abstract Background Pulse oximetry is routinely used to continuously and noninvasively monitor arterial oxygen saturation (SaO2 in critically ill patients. Although pulse oximeter oxygen saturation (SpO2 has been studied in several patient populations, including the critically ill, its accuracy has never been studied in emergency department (ED patients with severe sepsis and septic shock. Sepsis results in characteristic microcirculatory derangements that could theoretically affect pulse oximeter accuracy. The purposes of the present study were twofold: 1 to determine the accuracy of pulse oximetry relative to SaO2 obtained from ABG in ED patients with severe sepsis and septic shock, and 2 to assess the impact of specific physiologic factors on this accuracy. Methods This analysis consisted of a retrospective cohort of 88 consecutive ED patients with severe sepsis who had a simultaneous arterial blood gas and an SpO2 value recorded. Adult ICU patients that were admitted from any Calgary Health Region adult ED with a pre-specified, sepsis-related admission diagnosis between October 1, 2005 and September 30, 2006, were identified. Accuracy (SpO2 - SaO2 was analyzed by the method of Bland and Altman. The effects of hypoxemia, acidosis, hyperlactatemia, anemia, and the use of vasoactive drugs on bias were determined. Results The cohort consisted of 88 subjects, with a mean age of 57 years (19 - 89. The mean difference (SpO2 - SaO2 was 2.75% and the standard deviation of the differences was 3.1%. Subgroup analysis demonstrated that hypoxemia (SaO2 2 was in the 90-93% range the SaO2 was Conclusions Pulse oximetry overestimates ABG-determined SaO2 by a mean of 2.75% in emergency department patients with severe sepsis and septic shock. This overestimation is exacerbated by the presence of hypoxemia. When SaO2 needs to be determined with a high degree of accuracy arterial blood gases are recommended.

  16. Pulse Voltammetry.

    Science.gov (United States)

    Osteryoung, Janet

    1983-01-01

    Discusses the nature of pulse voltammetry, indicating that its widespread use arises from good sensitivity and detection limits and from ease of application and low cost. Provides analytical and mechanistic applications of the procedure. (JN)

  17. Pulmonary ultrasound and pulse oximetry versus chest radiography and arterial blood gas analysis for the diagnosis of acute respiratory distress syndrome: a pilot study

    OpenAIRE

    Bass, Cameron M.; Sajed, Dana R.; Adedipe, Adeyinka A.; West, T Eoin

    2015-01-01

    Introduction In low-resource settings it is not always possible to acquire the information required to diagnose acute respiratory distress syndrome (ARDS). Ultrasound and pulse oximetry, however, may be available in these settings. This study was designed to test whether pulmonary ultrasound and pulse oximetry could be used in place of traditional radiographic and oxygenation evaluation for ARDS. Methods This study was a prospective, single-center study in the ICU of Harborview Medical Center...

  18. Effects of Acupuncture Stimulation on the Radial artery’s Pressure Pulse Wave in Healthy Young Participants: Protocol for a prospective, single-Arm, Exploratory, Clinical Study

    OpenAIRE

    Jae-Young Shin; Boncho Ku; Tae-Hun Kim; Jang Han Bae; Min-Ho Jun; Jun-Hwan Lee; Kim, Jaeuk U.

    2016-01-01

    Introduction: This study aims to investigate the effects of acupuncture stimulation on the radial artery’s pressure pulse wave, along with various hemodynamic parameters, and to explore the possible underlying mechanism of pulse diagnosis in healthy participants in their twenties. Methods and analysis: This study is a prospective, single-arm, exploratory clinical study. A total of 25 healthy participants, without regard to gender, in their twenties will be recruited by physicians. Written inf...

  19. Conceptual moderator studies for the Spallation Neutron Source short-pulse second target station

    Science.gov (United States)

    Gallmeier, F. X.; Lu, W.; Riemer, B. W.; Zhao, J. K.; Herwig, K. W.; Robertson, J. L.

    2016-06-01

    Candidate moderator configurations for a short-pulse second target station (STS) at the Oak Ridge National Laboratory Spallation Neutron Source (SNS) have been identified using a global optimizer framework built around the MCNPX particle transport code. Neutron brightness metrics were selected as the figure-of-merit. We assumed that STS would use one out of six proton pulses produced by an SNS accelerator upgraded to operate at 1.3 GeV proton energy, 2.8 MW power and 60 Hz repetition rate. The simulations indicate that the peak brightness can be increased by a factor of 5 and 2.5 on a per proton pulse basis compared to the SNS first target station for both coupled and decoupled para-hydrogen moderators, respectively. Additional increases by factors of 3 and 2 were demonstrated for coupled and decoupled moderators, respectively, by reducing the area of neutron emission from 100 × 100 mm2 to 20 × 20 mm2. This increase in brightness has the potential to translate to an increase of beam intensity at the instruments' sample positions even though the total neutron emission of the smaller moderator is less than that of the larger. This is especially true for instruments with small samples (beam dimensions). The increased fluxes in the STS moderators come at accelerated poison and de-coupler burnout and higher radiation-induced material damage rates per unit power, which overall translate into lower moderator lifetimes. A first effort was undertaken to group decoupled moderators into a cluster collectively positioning them at the peak neutron production zone in the target and having a three-port neutron emission scheme that complements that of a cylindrical coupled moderator.

  20. Conceptual moderator studies for the Spallation Neutron Source short-pulse second target station.

    Science.gov (United States)

    Gallmeier, F X; Lu, W; Riemer, B W; Zhao, J K; Herwig, K W; Robertson, J L

    2016-06-01

    Candidate moderator configurations for a short-pulse second target station (STS) at the Oak Ridge National Laboratory Spallation Neutron Source (SNS) have been identified using a global optimizer framework built around the MCNPX particle transport code. Neutron brightness metrics were selected as the figure-of-merit. We assumed that STS would use one out of six proton pulses produced by an SNS accelerator upgraded to operate at 1.3 GeV proton energy, 2.8 MW power and 60 Hz repetition rate. The simulations indicate that the peak brightness can be increased by a factor of 5 and 2.5 on a per proton pulse basis compared to the SNS first target station for both coupled and decoupled para-hydrogen moderators, respectively. Additional increases by factors of 3 and 2 were demonstrated for coupled and decoupled moderators, respectively, by reducing the area of neutron emission from 100 × 100 mm(2) to 20 × 20 mm(2). This increase in brightness has the potential to translate to an increase of beam intensity at the instruments' sample positions even though the total neutron emission of the smaller moderator is less than that of the larger. This is especially true for instruments with small samples (beam dimensions). The increased fluxes in the STS moderators come at accelerated poison and de-coupler burnout and higher radiation-induced material damage rates per unit power, which overall translate into lower moderator lifetimes. A first effort was undertaken to group decoupled moderators into a cluster collectively positioning them at the peak neutron production zone in the target and having a three-port neutron emission scheme that complements that of a cylindrical coupled moderator.

  1. Conceptual moderator studies for the Spallation Neutron Source short-pulse second target station

    Energy Technology Data Exchange (ETDEWEB)

    Gallmeier, F. X., E-mail: gallmeierfz@ornl.gov; Lu, W.; Riemer, B. W.; Zhao, J. K.; Herwig, K. W.; Robertson, J. L. [Instrument and Source Division, Oak Ridge National Laboratory, P.O. Box 2008, MS6466, Oak Ridge, Tennessee 37831 (United States)

    2016-06-15

    Candidate moderator configurations for a short-pulse second target station (STS) at the Oak Ridge National Laboratory Spallation Neutron Source (SNS) have been identified using a global optimizer framework built around the MCNPX particle transport code. Neutron brightness metrics were selected as the figure-of-merit. We assumed that STS would use one out of six proton pulses produced by an SNS accelerator upgraded to operate at 1.3 GeV proton energy, 2.8 MW power and 60 Hz repetition rate. The simulations indicate that the peak brightness can be increased by a factor of 5 and 2.5 on a per proton pulse basis compared to the SNS first target station for both coupled and decoupled para-hydrogen moderators, respectively. Additional increases by factors of 3 and 2 were demonstrated for coupled and decoupled moderators, respectively, by reducing the area of neutron emission from 100 × 100 mm{sup 2} to 20 × 20 mm{sup 2}. This increase in brightness has the potential to translate to an increase of beam intensity at the instruments’ sample positions even though the total neutron emission of the smaller moderator is less than that of the larger. This is especially true for instruments with small samples (beam dimensions). The increased fluxes in the STS moderators come at accelerated poison and de-coupler burnout and higher radiation-induced material damage rates per unit power, which overall translate into lower moderator lifetimes. A first effort was undertaken to group decoupled moderators into a cluster collectively positioning them at the peak neutron production zone in the target and having a three-port neutron emission scheme that complements that of a cylindrical coupled moderator.

  2. Electronic and optical studies of pulse laser deposited ZnO/NiO bilayer film

    Science.gov (United States)

    Baraskar, P.; Dar, T. A.; Choudhary, R. J.; Sen, P. K.; Sen, P.

    2016-10-01

    We report the structural, optical and electronic properties of polycrystalline ZnO and NiO thin films and amorphous ZnO/NiO bilayer film, prepared by pulsed laser deposition technique. Despite of the presence of both Zn and Ni in +2 state in the bilayer film, the grown bilayer shows no reflections (in XRD) corresponding to ZnO or NiO. The difference in crystal structure of ZnO and NiO leads to the strain in the grown bilayer film. An increase in the band gap has been observed in bilayer film which can be attributed to the amorphous nature of the structure.

  3. THEORY AND EXPERIMENTAL STUDY OF THE SELF-EXCITED OSCILLATION PULSED JET NOZZLE

    Institute of Scientific and Technical Information of China (English)

    Liao Zhenfang; Li Jun; Chen Deshu; Deng Xiaogang; Tang Chuanlin; Zhang Fenghua

    2003-01-01

    Comparing with usual continuous jet nozzle, the self-excited oscillation pulsed jet nozzle SEOPJN) can make jet generate a higher peak of pressure and larger scouring volume. And it can make jet increase the effective standoff distance, too. The basic theories of the SEOPJN are introduced.Some experimental results are shown. According to the results, using tricorn bits assembled the SEOPJN to drill oil well, the ROP increases by 8%~77%, and the rates of the footage for tricorn bit increases by 6.7%~44.0%.

  4. Pulse radiolysis and cyclic voltammetry studies of redox properties of phenothiazine radicals

    Energy Technology Data Exchange (ETDEWEB)

    Madej, Edyta [Gray Cancer Institute, PO Box 100, Mount Vernon Hospital, Northwood, Middlesex HA6 2JR (United Kingdom)]. E-mail: madej@gci.ac.uk; Wardman, Peter [Gray Cancer Institute, PO Box 100, Mount Vernon Hospital, Northwood, Middlesex HA6 2JR (United Kingdom)

    2006-09-15

    One-electron transfer equilibria between seven phenothiazines were characterized by pulse radiolysis, producing radical-cations via oxidation by Br{sub 2} {sup .-} or (SCN){sub 2} {sup .-} radicals. The reduction potentials of the phenothiazine radicals were determined by cyclic voltammetry. As an independent check, the redox equilibrium between one phenothiazine and the redox indicator ABTS was investigated. The data establish phenothiazines as useful indicators for radical redox properties. However, there are potential problems of aggregation, additional reactions with Br{sup -}/Br{sub 2} {sup .-} and reactivity of the radicals towards buffers or other nucleophiles.

  5. Ultrafast electron field emission from gold resonant antennas studied by two terahertz pulse experiments

    DEFF Research Database (Denmark)

    Iwaszczuk, Krzysztof; Zalkovskij, Maksim; Strikwerda, Andrew C.;

    2015-01-01

    Summary form only given. Ultrafast electron field emission from gold resonant antennas induced by strong terahertz (THz) transient is investigated using two THz pulse experiments. It is shown that UV emission from nitrogen plasma generated by liberated electrons is a good indication of the local...... electric field at the antenna tip. Using this method resonant properties of antennas fabricated on high resistivity silicon are investigated in the strong field regime. Decrease of antenna Q-factor due to ultrafast carrier multiplication in the substrate is observed....

  6. Study on Decomposition of Indoor Air Contaminants by Pulsed Atmospheric Microplasma

    OpenAIRE

    Tomoya Kuwabara; Marius Blajan; Kazuo Shimizu

    2012-01-01

    Decomposition of formaldehyde (HCHO) by a microplasma reactor in order to improve Indoor Air Quality (IAQ) was achieved. HCHO was removed from air using one pass through reactor treatment (5 L/min). From an initial concentration of HCHO of 0.7 ppm about 96% was removed in one pass treatment using a discharge power of 0.3 W provided by a high voltage amplifier and a Marx Generator with MOSFET switches as pulsed power supplies. Moreover microplasma driven by the Marx Generator did not generate ...

  7. Multifrequency Study of Giant Radio Pulses from the Crab Pulsar with K5 VLBI Recording Terminal

    CERN Document Server

    Popov, M V; Kondratiev, V I; Bilous, A V; Moshkina, O; Oreshko, V V; Ilyasov, Yu P; Sekido, M; Kondo, T

    2009-01-01

    Simultaneous multifrequency observations of the Crab pulsar giant pulses (GPs) were performed with the 64-m Kalyazin radio telescope at four frequencies 0.6, 1.4, 2.2 and 8.3 GHz using the K5 VLBI recording terminal. K5 terminal provided continuous recording in 16 4-MHz wide frequency channels distributed over 4 frequency bands. Several thousands of GPs were detected during about 6 hours of observations in two successive days in July 2005. Radio spectra of single GPs were analysed at separate frequencies and over whole frequency range. These spectra manifest notable modulation both on large ($\\Delta\

  8. Study on a 5.0 W/80 K single stage Stirling type pulse tube cryocooler

    Institute of Scientific and Technical Information of China (English)

    Zhi-hua GAN; Guo-jun LIU; Ying-zhe WU; Qiang CAO; Li-min QIU; Guo-bang CHEN; J.M.PFOTENHAUER

    2008-01-01

    A single stage Stifling pulse tube cryocooler was designed based on REGEN 3.2 and fabricated for testing.The experimental results show that the cooler can provide a cooling capacity of 5.0 W at 79.1 K,and produce a no-load temperature of 57.0 K,operating with an average pressure of 2.50 Mpa and a frequency of 60 Hz,performance results that are very close to the calculated values.The cryoeooler can be cooled from room temperature to 80 K in 8.5 min.The fast cooldown time is a result of the small regenerator.

  9. CEMS study on diluted magneto titanium oxide films prepared by pulsed laser deposition

    Science.gov (United States)

    Nomura, K.; Inaba, K.; Iio, S.; Hitosugi, T.; Hasegawa, T.; Hirose, Y.; Homonnay, Z.

    6% 57Fe doped titanium oxide films, prepared by pulsed laser deposition (PLD) on sapphire substrate at 650° under various vacuum conditions, were characterized mainly by conversion electron Mössbauer spectrometry (CEMS). Two magnetic sextets with hyperfine fields 33 and 29 T, and one doublet were observed in the CEMS spectra of Ti02 films prepared under P02=10-6 and 10-8 torr, which showed ferromagnetism at room temperature, whereas only the doublet of paramagnetic Fe3+ species was observed for the film prepared under P02=10-1 torr.

  10. Pulsed magnetic field study of the spin gap in intermediate valence compound SmB 6

    Science.gov (United States)

    Flachbart, K.; Bartkowiak, M.; Demishev, S.; Gabani, S.; Glushkov, V.; Herrmannsdorfer, T.; Moshchalkov, V.; Shitsevalova, N.; Sluchanko, N.

    2009-10-01

    In this work, we report the behavior of electrical resistivity of SmB 6 at temperatures between 2.2 and 70 K in pulsed magnetic fields up to 54 T. A strong negative magnetoresistance was detected with increasing magnetic field, when lowering the temperature in the range T30 K is discussed within the framework of exciton-polaron model of local charge fluctuations in SmB 6 proposed by Kikoin and Mishchenko. It seems that these exciton-polaron in-gap states are influenced both by temperature and magnetic field.

  11. Neutron scattering studies of the dynamics of biopolymer-water systems using pulsed-source spectrometers

    Energy Technology Data Exchange (ETDEWEB)

    Middendorf, H.D. [Univ. of Oxford (United Kingdom); Miller, A. [Stirling Univ., Stirling (United Kingdom)

    1994-12-31

    Energy-resolving neutron scattering techniques provide spatiotemporal data suitable for testing and refining analytical models or computer simulations of a variety of dynamical processes in biomolecular systems. This paper reviews experimental work on hydrated biopolymers at ISIS, the UK Pulsed Neutron Facility. Following an outline of basic concepts and a summary of the new instrumental capabilities, the progress made is illustrated by results from recent experiments in two areas: quasi- elastic scattering from highly hydrated polysaccharide gels (agarose and hyaluronate), and inelastic scattering from vibrational modes of slightly hydrated collagen fibers.

  12. Study of rapid transient explosive boiling under short-pulsed laser heating

    Institute of Scientific and Technical Information of China (English)

    JIN Renxi; HUAI Xiulan; LIU Dengying

    2004-01-01

    Using acetone, ethanol, water and acetone-water mixture as test liquids, the rapid transient explosive boiling (RTEB) taking place under short-pulsed laser heating is observed in experiment. The behaviors of temperature variation are investigated via transient temperature measurement. The vapor bubble behaviors of RTEB are captured by high-speed photography, and the difference between RTEB and normal boiling is analyzed. The boiling heat transfer of RTEB is also discussed. It shows that the character of RTEB is far different from normal boiling.

  13. Reaction of hydroxyl radical with phenylpropanoid glycosides from Pedicularis species: a pulse radiolysis study

    Institute of Scientific and Technical Information of China (English)

    王潘奋; 郑荣梁; 高建军; 贾忠建; 王文峰; 姚思德; 张加山; 林念芸

    1996-01-01

    Using pulse radiolysis technique, the reaction between hydroxyl radical and 7 phenylpropanoidglycosides: echinacoside, verbascoside, leucosceptoside A, martynoside, pediculariosides A, M and N which were isolated from Pedicularis were examined. The rate constants of these reactions were determined by transient absorption spectra. All 7 phenylpropanoid glycosides react with hydroxyl radical at high rate constants within (0.97-1.91)×1010L · mol-1 · s-1. suggesting that they are effective hydroxyl radical scavengers. The results demonstrate that the numbers of phenolic hydroxyl groups of phenylpropanoid glycosides are directly related to their scavenging activities. The scavenging activities are likely related to o-dihydroxy group of phenylpropanoid glycosides as well.

  14. Studies on laser material processing with nanosecond and sub-nanosecond and picosecond and sub-picosecond pulses

    Science.gov (United States)

    Zhang, Jie; Tao, Sha; Wang, Brian; Zhao, Jay

    2016-03-01

    In this paper, laser ablation of widely used metal (Al, Cu. stainless-steel), semiconductor (Si), transparent material (glass, sapphire), ceramic (Al2O3, AlN) and polymer (PI, PMMA) in industry were systematically studied with pulse width from nanosecond (5-100ns), picosecond (6-10ps) to sub-picosecond (0.8-0.95ps). A critical damage zone (CDZ) of up to 100um with ns laser, price. Our studies of cutting and drilling with ns, ps, and sub-ps lasers indicate that it is feasible to achieve user accepted quality and speed with cost-effective and reliable laser by optimizing processing conditions.

  15. Weekly azathioprine pulse versus daily azathioprine in the treatment of Parthenium dermatitis: A non-inferiority randomized controlled study

    Directory of Open Access Journals (Sweden)

    Kaushal K Verma

    2015-01-01

    Full Text Available Background: Azathioprine in daily doses has been shown to be effective and safe in the treatment of Parthenium dermatitis. Weekly pulses of azathioprine (WAP are also effective, but there are no reports comparing the effectiveness and safety of these two regimens in this condition. Aims: To study the efficacy and safety of WAP and daily azathioprine in Parthenium dermatitis. Methods: Sixty patients with Parthenium dermatitis were randomly assigned to treatment with azathioprine 300 mg weekly pulse or azathioprine 100 mg daily for 6 months. Patients were evaluated every month to assess the response to treatment and side effects. Results: The study included 32 patients in the weekly azathioprine group and 28 in the daily azathioprine group, of whom 25 and 22 patients respectively completed the study. Twenty-three (92% patients on WAP and 21 (96% on daily azathioprine had a good or excellent response. The mean pretreatment clinical severity score decreased from 26.4 ± 14.5 to 4.7 ± 5.1 in the WAP group, and from 36.1 ± 18.1 to 5.7 ± 6.0 in the daily azathioprine group, which was statistically significant and comparable (P = 0.366. Patients on WAP had a higher incidence of adverse effects (P = 0.02. Limitations: The study had a small sample size and the amount of clobetasol propionate used in each patient was not determined, though it may not have affected the study outcome due to its comparable use in both groups. Conclusions: Azathioprine 300 mg weekly pulse and 100 mg daily dose are equally effective and safe in the treatment of Parthenium dermatitis.

  16. Assessment of resolution and intercenter reproducibility of results of genotyping Staphylococcus aureus by pulsed-field gel electrophoresis of SmaI macrorestriction fragments: a multicenter study

    NARCIS (Netherlands)

    A.F. van Belkum (Alex); S. Salmenlinna; M. Kooistra; B. Cookson (Barry); W. Witte; N. El Solh; F. Forey; J. Etienne (Jerome); R. Goering; A. Morvan; M. Struelens; J. Vuopio-Varkila; F.C. Tenover (Fred); C. Steward; N. Legakis; A. Talens; F. O'Brien (Frances); P. Tassios; R. de Ryck; W. Grubb; M.E. Kaufmann; H.A. Verbrugh (Henri); W.B. van Leeuwen (Willem)

    1998-01-01

    textabstractTwenty well-characterized isolates of methicillin-resistant Staphylococcus aureus were used to study the optimal resolution and interlaboratory reproducibility of pulsed-field gel electrophoresis (PFGE) of DNA macrorestriction fragments. Five identical

  17. Comparative Study on the Pulse Wave Variables and Sasang Constitution in Cerebral Infarction Patients and Healthy Subjects

    Directory of Open Access Journals (Sweden)

    Ko KiDuk

    2007-06-01

    Full Text Available This study was performed to determine whether a pulse analyzer was useful 1 to characterize the variables of pulse wave of cerebral infarction patieno (CI, compared with those of healthy subjects, as well as 2 to determine Sasang Constitution in CI and healthy subjects. 1. Calibrated in Gwan, the amount of energy(Energy, height of main peak(H1, height of aorticvalley(H2, height of aortic peak(H3, total area of pulse wave(At, and area of main peak width(Aw of the CI group were higher than those of the healthy group. 2. Calibrated in Cheek, Energy, H1, H2, H3, height of valve valley(H4, At, Aw, and main peak angle(MPA of the CI group were higher than those of the healthy group. 3. Among the healthy (subjects group, Taeumin showed the highest contact pressure(CP and height of valve peak(H5 calibrated in Chon. The main peak width divided by whole time of pulse wave(MPW/T calibrated in Gwan and Cheok, was highest in Soyangin and was lowest in Taeumin. The H3 divided by H1(H3/H1 and the time to valve valley minus the time to main peak and divided by T[(T4-T1/T] calibrated in Cheek were highest in Soyangin. The time to main peak(T1 was longest in Soumin. 4. Among the CI group, At calibrated in Chon was widest in Taeumin and was narrowest in Soumin The time to aortic peak(T3 calibrated in Cheek was longest in Soumin and was shortest in Soyangin. The time to valve peak(T5 was shortest in Soyangin. 5. There were main effects of cerebral infarction in the area of systolic period(As and area of diastolic period(Ad calibrated in Chon, Energy calibrated in Cwan, and Energy, H1, H2, H3, (H4+H5/Hl, and MPA calibrated in Cheek. 6. There were main effects of Sasang Constitution in (T4-T1/T, area of systolic period(As, and Ad calibrated in Chon. 7. The interactions between the cerebral infarction and Sasang Constitution were observed in H5/H1 , T, At, As, Ad, and MPA calibrated in Chon, H4, T4, (T4-T1/T, As, and Ad calibrated in Cwan, and 74,75, and MPW calibrated

  18. A comparative study of pulse rate variability and heart rate variability in healthy subjects.

    Science.gov (United States)

    Wong, Jih-Sen; Lu, Wan-An; Wu, Kung-Tai; Liu, Margaret; Chen, Gau-Yang; Kuo, Cheng-Deng

    2012-04-01

    Both heart rate variability (HRV) and pulse rate variability (PRV) are noninvasive means for the assessment of autonomic nervous control of the heart. However, it is not settled whether or not the PRV obtained from either hand can be the surrogate of HRV. The HRV measures obtained from electrocardiographic signals and the PRV measures obtained from the pulse waves recorded from the index fingers of both hands were compared in normal subjects by using linear regression analysis and Bland and Altman method. Highly significant correlations (P < 0.001, 0.89 < r < 1.0) were found between all HRV measures and the corresponding PRV measures of both hands. However, there were insufficient agreements in some measures between pairwise comparisons among HRV, right PRV and left PRV except heart rate and ultra-low frequency power (ULFP). The PRV of either hand is close to, but not the same as the HRV in healthy subjects. The HRV, right PRV and left PRV are not surrogates of one another in normal subjects except heart rate and ULFP. Since HRV is generally accepted as the standard method for the assessment of the autonomic nervous modulation of a subject, the PRV of either hand may not be suitable for the assessment of the cardiac autonomic nervous modulation of the subject.

  19. Theoretical study of rectangular pulse electrical stimulation (RPES) onskin cells (in vivo) under conforming electrodes.

    Science.gov (United States)

    Cheng, K; Tarjan, P P; Mertz, P M

    1993-01-01

    Our previous in vivo experimental results have shown RPES can enhance skin wound healing by using conforming electrodes. Based on an equation of polarization transmembrane voltage [Cole, K. S. 1972], two equations were derived to describe the peak RPES intensity on skin cells in vivo: (1) U = 1.5 a J/sigma, (2) Jm = 1.5 a (J/sigma) (Cm/tau). Where U: polarization transmembrane voltage. a: radius (R) for spherical cells or semi-length (L) for long fibers parallel to the electrical field. J: external imposed pulse current density under the electrode. sigma: average conductivity of skin tissue. Jm: transmembrane displacement current density. Cm: membrane capacitance per unit area and tau: time constant. Calculations indicated that the sensory fibers (SF) would receive the strongest stimulation compared to other cells in skin since generally LSF > or = 100 R. The sensitivity of SF to the stimulation could enhance skin wound healing as well as protect normal skin cells from harmful electroporation. From these theoretical calculations. We proposed a theoretical range of the pulse current density as: U1 sigma/(1.5 L) < or = J < or = U2 sigma/(1.5 L), where U1 and U2 are the excitation threshold voltage (about 0.01 V) and polarization electroporation voltage (about 0.1 V) for a SF respectively, for RPES to enhance skin wound healing.

  20. In vitro study of the variable square pulse Er:YAG laser cutting efficacy for apicectomy.

    Science.gov (United States)

    Grgurević, Josko; Grgurević, Lovro; Miletić, Ivana; Karlović, Zoran; Krmek, Silvana Jukić; Anić, Ivica

    2005-06-01

    Variable square pulse (VSP) Er:YAG laser should be quicker than older Er:YAG lasers. The objectives were: (1) comparison of VSP laser and mechanical handpiece efficacy for apicectomy and (2) determination of optimal pulse width/energy/frequency combination. Sixty extracted, single-rooted mature human teeth with round apical parts were instrumented, root filled, cleaned, and divided into four groups. Apical 2 mm of each root were apicectomized with mechanical handpiece and Er:YAG laser with three different settings (LaserA = 200 mJ/300 microseconds/ 8 Hz; LaserB = 200 mJ/100 microseconds/8 Hz; LaserC = 380 mJ/100 microseconds/20 Hz). Timing results were statistically compared. LaserC was the most efficient setting. Differences between groups were significant except between LaserC-Mechanical and LaserA-LaserC (P apicectomy is slower by a factor of 7-31 than mechanical handpiece, but treatment outcome is acceptable. Optimal settings for apicectomy with VSP laser are 380 mJ/100 microseconds/20 Hz. Copyright 2005 Wiley-Liss, Inc.

  1. DC Studies of Coaxial Vacuum Gap Breakdown for Pulsed Power Liners

    Science.gov (United States)

    Meisenhelder, C. M.; Bott-Suzuki, S. C.; Haas, D. M.

    2013-10-01

    Previously, pulsed power loads for inertial fusion have been envisioned as cylindrical wire arrays, which could easily be constrained to be in contact with both electrodes for a good electrical connection. Recently, solid liners have become the load of choice for Magnetized Liner Inertial Fusion (MagLIF) experiments which are currently being conducted on the Z-Machine at Sandia National Laboratory. These liners cannot easily be constrained as previous wire loads were, particularly for a repetitive system. The result is a vacuum gap between the driver electrodes and load, which may have unknown effects on the stability and development of the plasma system. DC voltages up to 30 kV will be applied to coaxial electrodes in vacuum to simulate a variety of possible gap parameters for pulsed power liners. This work investigates the breakdown-timing, azimuthal symmetry and coupling of the driver energy to the load as a function of gap parameters to better understand the subsequent behavior of a liner load. Supported by the National Undergraduate Fellowship Program in Plasma Physics and Fusion Energy Sciences and under DE-NA0001836 and GA IR&D funding.

  2. Experimental Study of Coherent Summation of Radiation from Two Widely Aperture Pulsed

    Directory of Open Access Journals (Sweden)

    V.E. Rogalin

    2014-07-01

    Full Text Available Emission of two high-power pulsed CO2-lasers with a transverse discharge at atmospheric pressure in the active medium and the output beam aperture 100  100 mm, united by a joint unstable telescopic resonator, was coherently summarized under conditions of real ground-level trackon the screen surface, which was remote from output mirror of the laser at a distance of 263 m. Output Brewster windows of laser cuvettes were manufactured from single-crystal plates of sodium chloride which had a diameter of 300 mm. Mirrors for resonator and optical circuit were manufactured from oxygen-free copper. Active medium - a mixture of gases: CO2: N2: He in the ratio 1 : 2 : 3. Laser pulse duration is 5 microseconds. During the experiment, when summing on the screen 2-laser beams at the lowest possible convergence angle of rays, the interference pattern was registered.

  3. NATO Advanced Study Institute on Chemical Crystallography with Pulsed Neutrons and Synchrotron X-Rays

    CERN Document Server

    Jeffrey, George

    1988-01-01

    X-ray and neutron crystallography have played an increasingly impor­ tant role in the chemical and biochemical sciences over the past fifty years. The principal obstacles in this methodology, the phase problem and com­ puting, have been overcome. The former by the methods developed in the 1960's and just recognised by the 1985 Chemistry Nobel Prize award to Karle and Hauptman, the latter by the dramatic advances that have taken place in computer technology in the past twenty years. Within the last decade, two new radiation sources have been added to the crystallographer's tools. One is synchrotron X-rays and the other is spallation neutrons. Both have much more powerful fluxes than the pre­ vious sources and they are pulsed rather than continuos. New techniques are necessary to fully exploit the intense continuos radiation spectrum and its pulsed property. Both radiations are only available from particular National Laboratories on a guest-user basis for scientists outside these Na­ tional Laboratories. Hi...

  4. Study on Nanostructures Induced by High-Current Pulsed Electron Beam

    Directory of Open Access Journals (Sweden)

    Bo Gao

    2012-01-01

    Full Text Available Four techniques using high-current pulsed electron beam (HCPEB were proposed to obtain surface nanostructure of metal and alloys. The first method involves the distribution of several fine Mg nanoparticles on the top surface of treated samples by evaporation of pure Mg with low boiling point. The second technique uses superfast heating, melting, and cooling induced by HCPEB irradiation to refine the primary phase or the second phase in alloys to nanosized uniform distributed phases in the matrix, such as the quasicrystal phase Mg30Zn60Y10 in the quasicrystal alloy Mg67Zn30Y3. The third technique involves the refinement of eutectic silicon phase in hypereutectic Al-15Si alloys to fine particles with the size of several nanometers through solid solution and precipitation refinement. Finally, in the deformation zone induced by HCPEB irradiation, the grain size can be refined to several hundred nanometers, such as the grain size of the hypereutectic Al-15Si alloys in the deformation zone, which can reach ~400 nm after HCPEB treatment for 25 pulses. Therefore, HCPEB technology is an efficient way to obtain surface nanostructure.

  5. Study of the shower maximum depth by the method of detection of the EAS Cerenkov light pulse shape

    Science.gov (United States)

    Aliev, N.; Alimov, T.; Kakhkharov, M.; Khakimov, N.; Makhmudov, B. M.; Rakhimova, N.; Tashpulatov, R.; Khristiansen, G. B.; Prosin, V. V.; Zhukov, V. Y.

    1985-01-01

    The results of processing the data on the shape of the EAS Cerenkov light pulses recorded by the extensive air showers (EAS) array are presented. The pulse FWHM is used to find the mean depth of EAS maximum.

  6. Schlieren study of a sonic jet injected into a supersonic cross flow using high-current pulsed LEDs

    CERN Document Server

    Giskes, Ella; Segerink, Frans B; Venner, Cornelis H

    2016-01-01

    In the research of supersonic flows, flow visualization continues to be an important tool, and even today it is difficult to create high quality images. In this study we present a low-cost and easy-to use Schlieren setup. The setup makes use of LEDs, pulsed with high currents to increase the optical output to sufficient levels, exploiting the advantages of LED light over conventional light sources. As a test-case we study the interaction of a Mach 1.7 cross flow and a transverse underexpanded jet, which is commonly studied considering the mixing and combustion in scramjet engines. Using 130 nanosecond LED light pulses, we captured the flow structures sharply and in great detail. We observed a large-gradient wave, which was seen in numerical studies but hitherto not reported in experiments. Furthermore, we demonstrate that time-correlated images can be obtained with this Schlieren setup, so that also flow unsteadiness can be studied, such as the movement of shock waves and vortices.

  7. The Study on the Variation of the Cavity Length's Influence on the Output Pulse Train of the Actively Mode-Locked Fiber Laser

    Institute of Scientific and Technical Information of China (English)

    LUO Hong-e; TIAN Xiao-jian; GAO Bo

    2005-01-01

    The influence of actively mode-locked Erbium-Doped Fiber Laser(EDFL) cavity length variation on the noises of an optical pulse train is investigated, in theory and in MATLAB simulation. Using a simple model, the noise characteristics of the output pulse train are studied. The results show that the noises of the output pulse train increase with the increasing of the variation of the cavity length. The theory analysis and the simulation results agree well. This result is very significant for us to improve the reliability and the stability of the actively mode-locked fiber laser.

  8. RF Pulsed Heating

    Energy Technology Data Exchange (ETDEWEB)

    Pritzkau, David P.

    2002-01-03

    RF pulsed heating is a process by which a metal is heated from magnetic fields on its surface due to high-power pulsed RF. When the thermal stresses induced are larger than the elastic limit, microcracks and surface roughening will occur due to cyclic fatigue. Pulsed heating limits the maximum magnetic field on the surface and through it the maximum achievable accelerating gradient in a normal conducting accelerator structure. An experiment using circularly cylindrical cavities operating in the TE{sub 011} mode at a resonant frequency of 11.424 GHz is designed to study pulsed heating on OFE copper, a material commonly used in normal conducting accelerator structures. The high-power pulsed RF is supplied by an X-band klystron capable of outputting 50 MW, 1.5 {micro}s pulses. The test pieces of the cavity are designed to be removable to allow testing of different materials with different surface preparations. A diagnostic tool is developed to measure the temperature rise in the cavity utilizing the dynamic Q change of the resonant mode due to heating. The diagnostic consists of simultaneously exciting a TE{sub 012} mode to steady-state in the cavity at 18 GHz and measuring the change in reflected power as the cavity is heated from high-power pulsed RF. Two experimental runs were completed. One run was executed at a calculated temperature rise of 120 K for 56 x 10{sup 6} pulses. The second run was executed at a calculated temperature rise of 82 K for 86 x 10{sup 6} pulses. Scanning electron microscope pictures show extensive damage occurring in the region of maximum temperature rise on the surface of the test pieces.

  9. Pulsed dye laser versus Nd:YAG laser in the treatment of plantar warts: a comparative study.

    Science.gov (United States)

    El-Mohamady, Abd El-Shakor; Mearag, Ibrahim; El-Khalawany, Mohamed; Elshahed, Ahmed; Shokeir, Hisham; Mahmoud, Anas

    2014-05-01

    Plantar warts are common viral infection that are usually challenging in treatment. Conventional treatment methods are usually invasive, have low efficacy, and need long recovery periods. In this study, we compared pulsed dye laser (PDL) and neodymium yttrium aluminum garnet (Nd:YAG) lasers in the treatment of recalcitrant plantar warts. The study included 46 patients with multiple plantar warts. In each patient, lesions were divided into two groups: one treated with Nd:YAG (spot size, 7 mm; energy, 100 J/cm(2); and pulse duration, 20 ms) and the other with PDL (spot size, 7 mm; energy, 8 J/cm(2); and pulse duration, 0.5 ms). Laser sessions were applied every 2 weeks with maximum of six sessions. The study included 63% males and 37% females with a mean age of 29.6 ± 7.34 years. The cure rate was 73.9% with PDL with no significant difference (p = 0.87) from Nd:YAG (78.3%). The number of sessions required was more in PDL (mean, 5.05 ± 0.2) compared with Nd:YAG (mean, 4.65 ± 0.5) but without significant difference. Complications were significantly higher with Nd:YAG (43.5%) compared with PDL (8.7%). Hematoma was the most common complication recorded by Nd:YAG (28.3 %), and it was significantly higher (p = 0.002) than PDL (2.2%). Relapse was recorded in 8.7% with Nd:YAG compared with 13% in PDL with no significant difference (p = 0.74). Our results suggested that PDL and Nd:YAG lasers are effective in the treatment of resistant plantar warts. PDL is safer and less painful but needs more sessions, while Nd:YAG is more painful and shows more complications.

  10. The effect of pulsed HIFU on the porosity and permeability of collagen gels: An in vitro study

    Science.gov (United States)

    Vipulanandan, Geethanjali; O'Neill, Brian E.

    2012-10-01

    Pulsed HIFU is hypothesized to alter permeability of the extracellular matrix by altering the collagen network. In this study, the ability of HIFU to disrupt the extracellular matrix, particularly Type I collagen, in vitro, was investigated in order to enhance the drug delivery to highly collagenous tumors. This was tested in vitro in two ways, first using dye penetration, and second, by confocal reflection microscopy. Based on the analyses, it was concluded that there was at least a three-fold increase in porosity of the collagen gels after HIFU treatment.

  11. Studies on photoinduced effects in pulse-electrodeposited Ag/Hg-1212/CdSe hetero-nanostructures

    Indian Academy of Sciences (India)

    D D Shivagan; P M Shirage; S H Pawar

    2002-05-01

    Metal/superconductor/semiconductor (Ag/Hg-1212/CdSe) hetero-nanostructures have been fabricated using pulse-electrodeposition technique and are characterized by X-ray diffraction (XRD), full-width at half-maximum (FWHM) and scanning electron microscopy (SEM) studies. The junction capacitance of Ag/Hg-1212, Hg-1212/CdSe and Ag/Hg-1212/CdSe heterojunctions is measured in dark and under laser irradiation at room temperature. The nature of the junction formed and built-in-junction potentials were determined. The increase in carrier concentration across the junction due to photo-irradiation has been observed.

  12. Numerical study on transverse asymmetry in the temperature profile of a regenerator in a pulse tube cooler

    DEFF Research Database (Denmark)

    Andersen, Stig Kildegård; Dietrich, M.; Carlsen, Henrik

    2007-01-01

    Transverse asymmetry in the temperature profile of the regenerator in a Stirling-type pulse tube cooler as observed in experiments was analysed in a numerical study. The asymmetry was reproduced using a one-dimensional model of the cooler where the regenerator was modelled using two identical...... parallel regenerator channels. The asymmetry was caused by a circulating flow that was superimposed on the oscillating flow. The primary mechanism driving the circulating flow was due to the wave form of the pressure difference between the ends of the regenerator and the dependence of the instantaneous...

  13. Numerical study on transverse asymmetry in the temperature profile of a regenerator in a pulse tube cooler

    Energy Technology Data Exchange (ETDEWEB)

    Andersen, Stig Kildegaard; Carlsen, Henrik [Department of Mechanical Engineering, Energy Engineering Section, Technical University of Denmark, Kgs. Lyngby (Denmark); Dietrich, Marc; Thummes, Guenter [Institute of Applied Physics, University of Giessen, D-35392 Giessen (Germany)

    2007-07-15

    Transverse asymmetry in the temperature profile of the regenerator in a Stirling-type pulse tube cooler as observed in experiments was analysed in a numerical study. The asymmetry was reproduced using a one-dimensional model of the cooler where the regenerator was modelled using two identical parallel regenerator channels. The asymmetry was caused by a circulating flow that was superimposed on the oscillating flow. The primary mechanism driving the circulating flow was due to the wave form of the pressure difference between the ends of the regenerator and the dependence of the instantaneous mass flow rate on the pressure difference and temperature. (author)

  14. Morphology and structural studies of WO3 films deposited on SrTiO3 by pulsed laser deposition

    Science.gov (United States)

    Kalhori, Hossein; Porter, Stephen B.; Esmaeily, Amir Sajjad; Coey, Michael; Ranjbar, Mehdi; Salamati, Hadi

    2016-12-01

    WO3 films have been grown by pulsed laser deposition on SrTiO3 (001) substrates. The effects of substrate temperature, oxygen partial pressure and energy fluence of the laser beam on the physical properties of the films were studied. Reflection high-energy electron diffraction (RHEED) patterns during and after growth were used to determine the surface structure and morphology. The chemical composition and crystalline phases were obtained by XPS and XRD respectively. AFM results showed that the roughness and skewness of the films depend on the substrate temperature during deposition. Optimal conditions were determined for the growth of the highly oriented films.

  15. Pulse radiolysis study on the mechanisms of reactions of CCl3OO· radical with quercetin, rutin and epigallocatechin gallate

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The mechanisms of reactions between CCl3OO· radical and quercetin, rutin and epigallocatechin gallate (EGCG) have been studied using pulse radiolytic technique. It is suggested that the electron transfer reaction is the main reaction between CCl3OO· radical and rutin, EGCG, but there are two main pathways for the reaction of CCl3OO· radical with quercetin, one is the electron transfer reaction, the other is addition reaction. The reaction rate constants were determined. It is proved that quercetin and rutin are better CCl3OO· radical scavengers than EGCG.

  16. A randomized double-blind prospective study of the efficacy of pulsed electromagnetic fields for interbody lumbar fusions

    Energy Technology Data Exchange (ETDEWEB)

    Mooney, V. (Univ. of California, Irvine (USA))

    1990-07-01

    A randomized double-blind prospective study of pulsed electromagnetic fields for lumbar interbody fusions was performed on 195 subjects. There were 98 subjects in the active group and 97 subjects in the placebo group. A brace containing equipment to induce an electromagnetic field was applied to patients undergoing interbody fusion in the active group, and a sham brace was used in the control group. In the active group there was a 92% success rate, while the control group had a 65% success rate (P greater than 0.005). The effectiveness of bone graft stimulation with the device is thus established.

  17. Monte Carlo study of impact ionization in InSb induced by intense ultrashort terahertz pulses

    Energy Technology Data Exchange (ETDEWEB)

    Asmontas, S.; Raguotis, R.; Bumeliene, S. [Center for Physical Sciences and Technology, Vilnius (Lithuania)

    2015-09-15

    The electron impact ionization dynamic has been investigated by Monte Carlo method in n-type InSb under the action of single-cycle pulses with 1 ps duration. The threshold electric field of impact ionization has been estimated to be about 8 kV/cm at 80 K. The number of generated carriers increases rapidly with increasing of electric field strength over threshold, and at 100 kV/cm, normalized electron concentration reaches 14. It is found that impact ionization process is dominant energy loss mechanism for hot carriers with energy larger than threshold energy of impact ionization. The results of calculations are compared with available experimental data. The agreement between theoretical calculations and experimental results was obtained. (orig.)

  18. Experimental study of transmission of a pulsed focused beam through a skull phantom in nonlinear regime

    Energy Technology Data Exchange (ETDEWEB)

    Tsysar, S. A., E-mail: sergey@acs366.phys.msu.ru; Nikolaeva, A. V.; Khokhlova, V. A.; Yuldashev, P. V. [Physics Faculty, Moscow State University, Leninskie Gory, Moscow 119991 (Russian Federation); Svet, V. D. [Andreyev Acoustics Institute, 4, Shvernik Street, Moscow 117036 (Russian Federation); Sapozhnikov, O. A. [Physics Faculty, Moscow State University, Leninskie Gory, Moscow 119991 (Russian Federation); Center for Industrial and Medical Ultrasound, Applied Physics Laboratory, University of Washington, 1013 NE 40th Street, Seattle, WA 98105 (United States)

    2015-10-28

    In the paper the use of receiving and radiating system, which allows to determine the parameters of bone by nonlinear pulse-echo technique and to image of brain structures through the skull bones, was proposed. Accuracy of the skull bone characterization is due to higher measured harmonic and is significantly better than in linear case. In the experimental part focused piezoelectric transducer with diameter 100 mm, focal distance 100 mm, the frequency of 1.092 MHz was used. It was shown that skull bone profiling can be performed with the use of 3rd harmonic since 1st harmonic can be used for visualization of the underlying objects. The use of wideband systems for both skull profiling and brain visualization is restricted by skull attenuation and resulting low effective sensitivity.

  19. Histochemical and polarization microscopic study of two cases of vegetable/pulse granuloma

    Directory of Open Access Journals (Sweden)

    Manjunatha B

    2008-01-01

    Full Text Available Vegetable granuloma (VG or pulse granuloma (PG results from the implantation of food particles of plant or vegetable origin. It is usually seen in the periapical or in the sulcus areas. These lesions have been described as a distinct entity and classified into central and peripheral lesions according to the location. Central lesions are asymptomatic, whereas peripheral lesions present as painless sub-mucosal swellings. Many authors have postulated that food particles in VG or PG get implanted and are rapidly digested, and sometimes partly get altered by host responses. The cellulose part of plant foods being indigestible persists in the form of hyaline material, whereas the starch matter gets digested. This cellulose moiety invokes chronic granulomatous response.

  20. Study on the Sensitivity of Landmine Electrical Fuse Circuit Under the Interference of Natural Electromagnetic Pulse

    Science.gov (United States)

    Qin, Dechun

    Landmine electrical fuse circuits on the battlefield will be interfered by natural electromagnetic pulse such as electrostatic discharge and lightning, which will undermine the circuit performance and trigger the early burst or mistaken burst of the landmines. In this paper, numerically simulation analysis is conducted on the electrostatic and lightning effects received by the landmine fuse circuit by means of building simulation model of the fuse circuit and analyzing the electric and magnetic field changes of the observation The mechanism of the influence of electrostatic discharge and lightning on the sensitivity of the fuse circuit is explored. The conclusion is that electrostatic effect cause the mistaken burst of the landmines by enabling the interference voltage to reach the components turn-on threshold and cause the circuit malfunction, and lighting effect by long period accumulation of energy.

  1. [Study of a wire-to-plate positive pulsed corona discharge reactor by emission spectroscopy].

    Science.gov (United States)

    Wang, Shen-Bing; Luo, Zhong-Yang; Zhao, Lei; Xuan, Jian-Yong; Jiang, Jian-Ping; Cen, Ke-Fa

    2011-11-01

    In order to get extensive knowledge of wire-to-plate pulsed corona discharge reactor, the influences of different diameters of wire electrode, different wire-to-plate and wire-to-wire spacing on OH radical generation were experimentally investigated under atmospheric pressure based on emission spectrum, and the spatial distribution of OH radicals in the electric field was also discussed in detail The results showed that OH radicals decrease along the X-axis, and the activation radius is approximately 20 mm; showing a trend of first increase and then decrease along the Y-axis, with the activation radius being more than 30 mm. OH radical has small change as the diameter of wire electrode changes below 2 mm, with a sharp decline as the diameter continues to increase. OH radical emission intensity increases as wire-to-wire spacing increases and decrease as wire-to-plate spacing increases.

  2. Study of structural and optical properties of ZnO films grown by pulsed laser deposition

    Energy Technology Data Exchange (ETDEWEB)

    Lemlikchi, S., E-mail: lemlikchi_safo@yahoo.fr [Advanced Technology Development Centre, Cite 20 Aout 1956 BP 17 Baba Hassen, Algiers (Algeria); Abdelli-Messaci, S.; Lafane, S.; Kerdja, T. [Advanced Technology Development Centre, Cite 20 Aout 1956 BP 17 Baba Hassen, Algiers (Algeria); Guittoum, A.; Saad, M. [Nuclear Research Centre of Algiers, 2 Bd Frantz-Fanon, Algiers (Algeria)

    2010-07-01

    Wurtzite zinc oxides films (ZnO) were deposited on silicon (0 0 1) and corning glass substrates using the pulsed laser deposition technique. The laser fluence, target-substrate distance, substrate temperature of 300 deg. C were fixed while varying oxygen pressures from 2 to 500 Pa were used. It is observed that the structural properties of ZnO films depend strongly on the oxygen pressure and the substrate nature. The film crystallinity improves with decreasing oxygen pressure. At high oxygen pressure, the films are randomly oriented, whereas, at low oxygen pressures they are well oriented along [0 0 1] axis for Si substrates and along [1 0 3] axis for glass substrates. A honeycomb structure is obtained at low oxygen pressures, whereas microcrystalline structures were obtained at high oxygen pressures. The effect of oxygen pressure on film transparency, band gap E{sub g} and Urbach energies was investigated.

  3. Experimental Study on Mechanical Characteristics of Coupling Pulsed Laser to Solid Targets

    Institute of Scientific and Technical Information of China (English)

    林丽云; 王声波; 吴鸿兴; 郭大浩; 戴宇生; 夏小平; 郭磊; 罗志成

    2003-01-01

    A set of experiments were designed to research on the mechanical characteristics of laser driving lightcraft,and the minimum laser power density needed to drive the lightcraft (weight 1.010 kg) is measured to be 71.986 ×109 W. cm-2 during the confined laser ablation of targets in vacuum. A set of parameters are discovered important to improve the propulsion efficiency, such as the restraint layers on the targets (the K9 glass is the optimal), and larger laser power density. In view of the impracticality of the confined ablation, we propose the applications of those target materials that cannot only produce powerful plasma propulsion but also can be used in repetitively pulsed laser.

  4. Matrix-assisted pulsed laser evaporation of polyimide thin films and the XPS study

    Institute of Scientific and Technical Information of China (English)

    WANG Wei; LI ChengXiang; ZHANG GuoBin; SHENG LiuSi

    2008-01-01

    Compared with the traditional thin film techniques, the matrix-assisted pulsed laser evaporation (MAPLE) technique has many advantages in the deposition of polymer and organic thin films. It has a wide range of applications in many fields, such as non-linear optics, luminescent devices, electronics, various sensors. We have successfully deposited polyimide thin films by using the MAPLE technique. These films were characterized with XPS. The XPS spectra showed that the single-photon effect is obvious at low laser fluence and the chemical bonds will be broken, resulting in decomposition of the films. Contrarily, the single-photon effect will decrease and the multi-photon effect and the photothermal effect will increase at high laser fluence, resulting in the protection of the structure of the polyimide thin films and the obvious decrease in decomposition. High laser fluence is more suitable for the deposition of polymer and organic thin films than low laser fluence.

  5. Multiscale modeling study of pulsed damage accumulation in alpha-Fe under inertial fusion conditions

    CERN Document Server

    Perlado, J M; Dominguez, E; Prieto, J; Caturla, M J; Díaz de la Rubia, T

    2002-01-01

    Reduced activation ferritic-martensitic (RAFM) steels are being considered as candidate materials for the first structural wall of a future fusion reactor, due to their high resistance to neutron irradiation. A combination of molecular dynamics and kinetic Monte Carlo has been utilized to analyze and assess the change and evolution of the microstructure in irradiated alpha-Fe, the main component of RAFM steels. We discuss how the pulse frequency, 1 and 10 Hz, may affect the damage production and accumulation. Dose rates of 0.1 and 0.01 dpa/s will be considered in order to represent the damage suffered by a protected first structural wall. These results will be compared with previous work on the subject and with those achieved with continuous irradiation at similar average dose rate.

  6. Spectroscopic characterization of mechanisms of oxidation of Phe by SO4- radical: A pulse radiolysis study

    Institute of Scientific and Technical Information of China (English)

    储高升; 韩镇辉; 都志文; 张淑娟; 姚思德; 张志成

    2002-01-01

    By using time-resolved kinetic spectrophotometry and pulse radiolysis technique, the oxidation of Phe by SO4- radical has been investigated both in aqueous and water/acetonitrilemixed solutions. The results reveal that attack of the oxidizing SO4- radical on Phe leads directlyto the formation of Phe cation radical 3 with a strong absorption peak at 310 nm, then it proceeds in three competitive reactions via either hydroxylation, deprotonation or decarboxylation, which were found to be strongly dependent upon the ionization state of the substitutes -COOH and -NH2 and the nature of the solvents. Decarboxylation takes place only when the carboxyl group is deprotonated. At high pH deprotonation of Phe cation radical 3 is much easier to occur than that in neutral or acid solutions. Moreover, with addition of acetonitrile, deprotonation is more predominant than hydroxylation, whereas in aqueous solutions hydroxylation is much easier to occur.

  7. Spectroscopic characterization of mechanisms of oxidation of Phe by SO.-4 radical: A pulse radiolysis study

    Institute of Scientific and Technical Information of China (English)

    储高升; 张淑娟; 姚思德; 韩镇辉; 都志文; 张志成

    2002-01-01

    By using time-resolved kinetic spectrophotometry and pulse radiolysis technique, the oxidation of Phe by radical has been investigated both in aqueous and water/acetonitrile mixed solutions. The results reveal that attack of the oxidizing SO4-radical on Phe leads directly to the formation of Phe cation radical 3 with a strong absorption peak at 310 nm, then it proceeds in three competitive reactions via either hydroxylation, deprotonation or decarboxylation, which were found to be strongly dependent upon the ionization state of the substitutes -COOH and -NH2 and the nature of the solvents. Decarboxylation takes place only when the carboxyl group is deprotonated. At high pH deprotonation of Phe cation radical 3 is much easier to occur than that in neutral or acid solutions. Moreover, with addition of acetonitrile, deprotonation is more predominant than hydroxylation, whereas in aqueous solutions hydroxylation is much easier to occur.

  8. Pulse radiolysis study on the free radical scavenging activities of puerarin

    Institute of Scientific and Technical Information of China (English)

    赵亚平; 王文锋; 于文利; 姚思德; 钱素平; 王大璞

    2003-01-01

    The free radical scavenging activities of puerarin towards nitrogen dioxide radicals , nitric oxide radicals (NO·) and hydroxyl radicals (OH·) were investigated by pulse radiolysis. Puerarin reacted with or NO·to form puerarin-4-O· with the absorption maximum at 340 nm, but reacted with OH·to form at least three transient species including puerarin-2-O·, puerarin-4-O· and [puerarin-OH]· with a broad absorption spectrum band (300-750 nm). In addition, the reaction rate constants of puerarin reacting with , NO·, and OH· were determined as 2.6×108, 1.7×108 and 3.9×109 L@mol·1@s·1, respectively.

  9. Matrix-assisted pulsed laser evaporation of polyimide thin films and the XPS study

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Compared with the traditional thin film techniques, the matrix-assisted pulsed laser evaporation (MAPLE) technique has many advantages in the deposition of polymer and organic thin films. It has a wide range of applications in many fields, such as non-linear optics, luminescent devices, electronics, various sensors. We have successfully deposited polyimide thin films by using the MAPLE technique. These films were characterized with XPS. The XPS spectra showed that the single-photon effect is ob-vious at low laser fluence and the chemical bonds will be broken, resulting in decomposition of the films. Contrarily, the single-photon effect will decrease and the multi-photon effect and the photothermal effect will increase at high laser fluence, resulting in the protection of the structure of the polyimide thin films and the obvious decrease in decomposition. High laser fluence is more suitable for the deposition of polymer and organic thin films than low laser fluence.

  10. Pulse plating

    CERN Document Server

    Hansal, Wolfgang E G; Green, Todd; Leisner, Peter; Reichenbach, Andreas

    2012-01-01

    The electrodeposition of metals using pulsed current has achieved practical importance in recent years. Although it has long been known that changes in potential, with or without polarity reversal, can significantly affect the deposition process, the practical application of this has been slow to be adopted. This can largely be explained in terms of the complex relationship between the current regime and its effect on the electrodeposition process. In order to harness these effects, an understanding of the anodic and cathodic electrochemical processes is necessary, together with the effects of polarity reversal and the rate of such reversals. In this new monograph, the basics of metal electrodeposition from solution are laid out in great detail in seven distinct chapters. With this knowledge, the reader is able to predict how a given pulse train profile can be adopted to achieve a desired outcome. Equally important is the choice of a suitable rectifier and the ancillary control circuits to enable pulse platin...

  11. Domiciliary pulse-oximetry at exacerbation of chronic obstructive pulmonary disease: prospective pilot study

    Directory of Open Access Journals (Sweden)

    Goldring James JP

    2010-10-01

    Full Text Available Abstract Background The ability to objectively differentiate exacerbations of chronic obstructive pulmonary disease (COPD from day-to-day symptom variations would be an important development in clinical practice and research. We assessed the ability of domiciliary pulse oximetry to achieve this. Methods 40 patients with moderate-severe COPD collected daily data on changes in symptoms, heart-rate (HR, oxygen saturation (SpO2 and peak-expiratory flow (PEF over a total of 2705 days. 31 patients had data suitable for baseline analysis, and 13 patients experienced an exacerbation. Data were expressed as multiples of the standard deviation (SD observed from each patient when stable. Results In stable COPD, the SD for HR, SpO2 and PEF were approximately 5 min-1, 1% and 10l min-1. There were detectable changes in all three variables just prior to exacerbation onset, greatest 2-3 days following symptom onset. A composite Oximetry Score (mean magnitude of SpO2 fall and HR rise distinguished exacerbation onset from symptom variation (area under receiver-operating characteristic curve, AUC = 0.832, 95%CI 0.735-0.929, p = 0.003. In the presence of symptoms, a change in Score of ≥1 (average of ≥1SD change in both HR and SpO2 was 71% sensitive and 74% specific for exacerbation onset. Conclusion We have defined normal variation of pulse oximetry variables in a small sample of patients with COPD. A composite HR and SpO2 score distinguished exacerbation onset from symptom variation, potentially facilitating prompt therapy and providing validation of such events in clinical trials.

  12. 双波长皮秒脉冲与可调谐脉宽产生的实验研究%Experimental study about generation of picosecond pulses with dual-wavelengths and tunable pulse-widths

    Institute of Scientific and Technical Information of China (English)

    郭志华; 罗春娅; 李丹; 凌福日

    2016-01-01

    In order to improve the practicability of multi-wavelength optical pulse equipment , a stable dual-wavelength semiconductor fiber ring laser was proposed and demonstrated by using dual-wavelength principle . Effects of ring cavity dispersion, filter pulse-width and modulation depth on output pulse were discussed .Experimental results are that repetition rate of dual-wavelength pulses is 5.0GHz and typical pulse-width is 20ps.Dual-wavelength pulses have good side-mode suppression ratios of 29.1dB ( at 1554.75nm) and 29.7dB ( at 1557.21nm) with typical output powers of -6.7dBm and -6.1dBm respectively.Output spectra are very stable with peak power fluctuation less than 0.5dB.This study is of great significance for the study of terahertz source and multi-wavelength optical pulse equipment .%为了提高多波长光脉冲设备的实用性,采用双波长工作原理,设计了一种稳定的双波长半导体环形光纤激光器. 讨论了环形腔色散、滤波器脉宽以及调制深度等对输出脉冲的影响. 结果表明,双波长光脉冲的重复率为5.0GHz,典型脉宽为20ps,双波长光脉冲具有良好的边模抑制比,当输出波长为1554.75nm和1557.21nm时,边模抑制比分别为29.1dB和29.7dB,其典型的输出功率分别为-6.7dBm和-6.1dBm,输出光谱的峰值功率波动小于0.5dB. 这项研究对太赫兹源和多波长光脉冲设备的研究具有借鉴意义.

  13. Routine immunization - do people know about it? A study among caretakers of children attending pulse polio immunization in east Delhi

    Directory of Open Access Journals (Sweden)

    Sharma Rahul

    2008-01-01

    Full Text Available Research question: Do caretakers of children under five years have sufficient knowledge regarding routine immunization (RI? Objective: To assess the knowledge about RI among caretakers of young children. Settings: Pulse polio immunization centres in East Delhi. Study design: Cross-sectional study. Participants: Six hundred and eighty-two caretakers accompanying children under 5 years to pulse polio booths in November 2006. Study tool: Pre-tested semi-open-ended questionnaire. Statistical analysis: Proportions, Chi-square test. Results: The proportions of respondents who had awareness about different aspects of RI, such as weekday of RI (37.0%, age group for RI (49.1%, number of visits required in the first year of life (27.0%, were all low. When asked to name the four diseases covered under the RI program in Delhi, only 268 (39.3% could name at least three. The education level of respondents was strongly associated with their knowledge about RI. Conclusion: The need of the hour is to make RI a ′felt need′ of the community. Making caretakers more aware about RI is a vital step in achieving this goal.

  14. Study of acoustic fingerprinting of nitromethane and some triazole derivatives using UV 266 nm pulsed photoacoustic pyrolysis technique

    Science.gov (United States)

    Rao, K. S.; Chaudhary, A. K.; Yehya, F.; Kumar, A. Sudheer

    2015-08-01

    We report a comparative study of acoustic fingerprints of nitromethane, nitrobenzene and some nitro rich triazole derivatives using pulsed photoacoustic technique. UV 266 nm wavelength i.e. Fourth harmonic of Q-switched Nd: YAG laser having pulse duration 7 ns and 10 Hz repetition rate is employed to record the time resolved PA spectrum. The PA fingerprint is produced due to absorption of incident UV light by molecule itself and photo dissociation of nitromethane and nitrobenzene at room temperature while in case of triazole it is attributed to the combination of thermal and photo-dissociation process. The entire dissociation process follows the root of cleavage of C-NO2 bond to produce free NO, NO2 and other by product gases due to π∗ ← n excitation. In addition, we have studied the thermal stability criteria of nitro rich triazoles based on the quality factor of acoustic resonance frequencies of the PA cavity. We have also studied the effect of data acquisition time to ascertain the decay behavior of HEMs samples.

  15. Tracking the fate of nitrate through pulse-flow wetlands: A mesocosm scale 15N enrichment tracer study

    Science.gov (United States)

    Messer, Tiffany L.; Burchell, Michael R.; Böhlke, John Karl; Tobias, Craig R.

    2017-01-01

    Quantitative information about the fate of applied nitrate (NO3-N) in pulse-flow constructed wetlands is essential for designing wetland treatment systems and assessing their nitrogen removal services for agricultural and stormwater applications. Although many studies have documented NO3-N losses in wetlands, controlled experiments indicating the relative importance of different processes and N sinks are scarce. In the current study, 15NO3-N isotope enrichment tracer experiments were conducted in wetland mesocosms of two different wetland soil types at two realistic agricultural NO3-N source loads. The 15N label was traced from the source NO3-N into plant biomass, soil (including organic matter and ammonium), and N-gas constituents over 7–10 day study periods. All sinks responded positively to higher NO3-N loading. Plant uptake exceeded denitrification 2–3 fold in the low NO3-N loading experiments, while both fates were nearly equivalent in the high loading experiments. One to two years later, soils largely retained the assimilated tracer N, whereas plants had lost much of it. Results demonstrated that plant and microbial assimilation in the soil (temporary N sinks) can exceed denitrification (permanent N loss) in pulse-flow environments and must be considered by wetland designers and managers for optimizing nitrogen removal potential.

  16. Effects of oxidation on copper-binding properties of Aβ1-16 peptide: a pulse radiolysis study.

    Science.gov (United States)

    Ramteke, S N; Ginotra, Y P; Walke, G R; Joshi, B N; Kumbhar, A S; Rapole, S; Kulkarni, P P

    2013-12-01

    The reaction of hydroxyl radicals ((•)OH) with Aβ1-16 peptide was carried out using pulse radiolysis to understand the effect of oxidation of peptide on its copper-binding properties. This reaction produced oxidized, dimeric and trimeric Aβ1-16 peptide species. The formation of these products was established with the help of fluorescence spectroscopy and mass spectrometry. The mass spectral data indicate that the major site of oxidation is at His6, while the site for dimerization is at Tyr10. Diethyl pyrocarbonate-treated Aβ1-16 peptide did not produce any trimeric species upon oxidation with (•)OH. The quantitative chemical modification studies indicated that one of the three histidine residues is covalently modified during pulse radiolysis. The copper-binding studies of the oxidized peptide revealed that it has similar copper-binding properties as the unoxidized peptide. Further, the cytotoxicity studies point out that both oxidized and unoxidized Aβ1-16 peptide are equally efficient in producing free radicals in presence of copper and ascorbate that resulted in comparable cell death.

  17. A useful method to monitor outputs from a pulsed light source and its application to rate effect studies in a photomultiplier tube

    CERN Document Server

    Takeuchi, Y; Kurashige, H; Matono, Y; Murakami, K; Nomura, T; Sakamoto, H; Sasao, N; Suehiro, M; Fukushima, Y; Ikegami, Y; Nakamura, T T; Taniguchi, T; Asai, M

    1999-01-01

    In order to study short-term gain stability in a photomultiplier tube at high counting rate, we constructed an LED pulsed light source and its output monitoring system. For the monitoring system, we employed a photon counting method using a photomultiplier as a monitor photon detector. It is found that the method offers a simple way to monitor outputs from a pulsed light source and that, together with an LED light source, it provides a useful method to investigate photomultiplier's rate effects.

  18. Sub-nanosecond time resolved light emission study for diffuse discharges in air under steep high voltage pulses

    Science.gov (United States)

    Tardiveau, P.; Magne, L.; Marode, E.; Ouaras, K.; Jeanney, P.; Bournonville, B.

    2016-10-01

    Pin-to-plane discharges in centimetre air gaps and standard conditions of pressure and temperature are generated under very high positive nanosecond scale voltage pulses. The experimental study is based on recordings of sub-nanosecond time resolved and Abel-processed light emission profiles and their complete correlation to electrical current waveforms. The effects of the voltage pulse features (amplitude between 20 and 90 kV, rise time between 2 and 5.2 ns, and time rate between 4 and 40 kV · ns‑1) and the electrode configuration (gap distance between 10 and 30 mm, pin radius between 10 and 200 µm, copper, molybdenum or tungsten pin material) are described. A three time period development can be found: a glow-like structure with monotonic light profiles during the first 1.5 ns whose size depends on time voltage rate, a shell-like structure with bimodal profiles whose duration and extension in space depends on rise time, and either diffuse or multi-channel regime for the connection to the cathode plane according to gap distance. The transition of the light from monotonic to bimodal patterns reveals the relative effects and dynamics of streamer space charge and external laplacian field. A classical 2D-fluid model for streamer propagation has been used and adapted for very high and steep voltage pulses. It shows the formation of a strong space charge (streamer) very close to the pin, but also a continuity of emission between the pin and the streamer, and electric fields higher than the critical ionization field (28 kV · cm‑1 in air) almost in the whole gap and very early in the discharge propagation.

  19. Neuronal excitation and permeabilization by 200-ns pulsed electric field: An optical membrane potential study with FluoVolt dye.

    Science.gov (United States)

    Pakhomov, Andrei G; Semenov, Iurii; Casciola, Maura; Xiao, Shu

    2017-07-01

    Electric field pulses of nano- and picosecond duration are a novel modality for neurostimulation, activation of Ca(2+) signaling, and tissue ablation. However it is not known how such brief pulses activate voltage-gated ion channels. We studied excitation and electroporation of hippocampal neurons by 200-ns pulsed electric field (nsPEF), by means of time-lapse imaging of the optical membrane potential (OMP) with FluoVolt dye. Electroporation abruptly shifted OMP to a more depolarized level, which was reached within 10s), so cells remained above the resting OMP level for at least 20-30s. Activation of voltage-gated sodium channels (VGSC) enhanced the depolarizing effect of electroporation, resulting in an additional tetrodotoxin-sensitive OMP peak in 4-5ms after nsPEF. Omitting Ca(2+) in the extracellular solution did not reduce the depolarization, suggesting no contribution of voltage-gated calcium channels (VGCC). In 40% of neurons, nsPEF triggered a single action potential (AP), with the median threshold of 3kV/cm (range: 1.9-4kV/cm); no APs could be evoked by stimuli below the electroporation threshold (1.5-1.9kV/cm). VGSC opening could already be detected in 0.5ms after nsPEF, which is too fast to be mediated by the depolarizing effect of electroporation. The overlap of electroporation and AP thresholds does not necessarily reflect the causal relation, but suggests a low potency of nsPEF, as compared to conventional electrostimulation, for VGSC activation and AP induction. Copyright © 2017 Elsevier B.V. All rights reserved.

  20. New Application of Actuator-Driven Pulsed Water Jet for Spinal Cord Dissection: An Experimental Study in Pigs.

    Science.gov (United States)

    Endo, Toshiki; Wenting, Jia; Nakagawa, Atsuhiro; Endo, Hidenori; Sagae, Yuto; Iwasaki, Masaki; Tominaga, Teiji

    2017-03-01

    Background Surgery for intramedullary tumors is technically demanding because it requires surgical resection along with functional preservation of the spinal cord. The water jet dissector is an emerging tool in neurologic surgeries and a novel tool in spinal cord surgeries. This article evaluates the usefulness and safety of water jet dissection in an experimental study. Methods A pulsed water jet was applied to dissect the posterior median sulcus of the spinal cords of seven anesthetized pigs. In four pigs, the water jet was delivered on the dorsal spinal cord at different input voltages (5, 10, and 15 V) and for durations of either 15 or 30 seconds. The depth and dissected areas were measured histologically and compared. In three separate pigs, somatosensory evoked potentials (SEPs) were recorded before and after dissection (10 V for 30 seconds) to evaluate the function of the dorsal column sensory pathway. Results Increased pressure and duration of exposure to the pulsed water jet led to deeper and wider dissection of the dorsal spinal cord. Application of the water jet at 5 or 10 V allowed precise dissection along the dorsal columns along with the preservation of microvasculature. During SEP monitoring, responses were maintained after application of the water jet to the posterior column at 10 V for 30 seconds. Conclusions The pulsed water jet is a feasible option for spinal cord dissection. Characteristics of this water jet may help surgeons achieve complete resection of intramedullary tumors along with preserving satisfactory postoperative neurologic functions. Georg Thieme Verlag KG Stuttgart · New York.