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Sample records for pulsed administration strategies

  1. Power Subscription Strategy: Administrator`s Record of Decision.

    Energy Technology Data Exchange (ETDEWEB)

    United States. Bonneville Power Administration

    1998-12-01

    The Bonneville Power Administration (BPA) has decided to adopt a Power Subscription Strategy for entering into new power sales contracts with its Pacific Northwest customers. The Strategy equitably distributes the electric power generated by the Federal Columbia River Power System (FCRPS) within the framework of existing law. The Power Subscription Strategy addresses the availability of power; describes power products; lays out strategies for pricing, including risk management; and discusses contract elements. In proceeding with this Subscription Strategy, BPA is guided by and committed to the Fish and Wildlife funding Principles for the BPA announced by the Vice President of the US in September 1998. This Record of Decision (ROD) addresses the issues raised by commenters who responded to BPA`s Power Subscription Strategy Proposal during and after the comment period that began with the release of the Proposal on September 18, 1998. The ROD is organized in approximately the same way as the Proposal and the Power Subscription Strategy that BPA developed based on the comments received. Abbreviations of party names used in citations appear in the section just preceding this introduction; a list of all the commenters follows the text of the ROD.

  2. Pulse-shaping strategies in short-pulse fiber amplifiers

    Energy Technology Data Exchange (ETDEWEB)

    Schimpf, Damian Nikolaus

    2010-02-09

    Ultrashort pulse lasers are an important tool in scientific and industrial applications. However, many applications are demanding higher average powers from these ultrashort pulse sources. This can be achieved by combining direct diode pumping with novel gain media designs. In particular, ultrashort pulse fiber lasers are now delivering average powers in the kW range. However, the design of fiber lasers, producing pulses with high peak-powers, is challenging due to the impact of nonlinear effects. To significantly reduce these detrimental effects in ultrashort pulse fiber amplifers, the combination of chirped pulse amplification (CPA) and large mode area fibers is employed. Using these methods, the pulse energy of fiber lasers has been steadily increasing for the past few years. Recently, a fiber-based CPA-system has been demonstrated which produces pulse energies of around 1 mJ. However, both the stretching and the enlargement of the mode area are limited, and therefore, the impact of nonlinearity is still noticed in systems employing such devices. The aim of this thesis is the analysis of CPA-systems operated beyond the conventional nonlinear limit, which corresponds to accumulated nonlinear phase-shifts around 1 rad. This includes a detailed discussion of the influence of the nonlinear effect self-phase modulation on the output pulse of CPA-systems. An analytical model is presented. Emphasis is placed on the design of novel concepts to control the impact of self-phase modulation. Pulse-shaping is regarded as a powerful tool to accomplish this goal. Novel methods to control the impact of SPM are experimentally demonstrated. The design of these concepts is based on the theoretical findings. Both amplitude- and phase-shaping are studied. Model-based phase-shaping is implemented in a state-of-the-art fiber CPA-system. The influence of the polarization state is also highlighted. Additionally, existing techniques and recent advances are put into context. (orig.)

  3. Evolution Strategies for Laser Pulse Compression

    NARCIS (Netherlands)

    Monmarché, Nicolas; Fanciulli, Riccardo; Willmes, Lars; Talbi, El-Ghazali; Savolainen, Janne; Collet, Pierre; Schoenauer, Marc; van der Walle, P.; Lutton, Evelyne; Back, Thomas; Herek, Jennifer Lynn

    2008-01-01

    This study describes first steps taken to bring evolutionary optimization technology from computer simulations to real world experimentation in physics laboratories. The approach taken considers a well understood Laser Pulse Compression problem accessible both to simulation and laboratory experiment

  4. The Strategy of In-School Administration.

    Science.gov (United States)

    Karklina, S. E.

    1989-01-01

    Advocates applying the theories of Anton S. Makarenko, an early influential Soviet educator, to the practice of school administration in the Soviet Union. Reviews Makarenko's theories, focusing on the establishment of a unified labor collective school, responsible for students' political socialization and character development. Stresses the…

  5. FAMILY BUSINESS ADMINISTRATION: USE OF SUPPORT STRATEGIES

    Directory of Open Access Journals (Sweden)

    Real, L.S.

    2015-06-01

    Full Text Available Every organization is subject to go through periods of crisis, and it becomes important now support the use of strategies that help the company and prepare it for the threats coming from the environment in which it operates. This study aims to verify the strategies used by companies providing services related to family-run companies in the central region of Rio Grande do Sul. The research is based on a multi-case study, qualitative and quantitative, and observation techniques and description of activities in companies. In addition, a questionnaire was applied with questions on the subject in focus, the managers of the participating companies. The study population consisted of service providers and the sample represented by twelve entities being characterized as random accessibility. The main results show that companies are aware of the markets that are inserted. This proven by the predominance of organizations that are high growth rate and rise in the market. There is also a confirmation of the diversity of strategies of stimuli that influence the development, use of strategies combinations and success in the same settings

  6. Environmental Strategies in Hotel Business Administration

    Directory of Open Access Journals (Sweden)

    Mirela STEFANICA

    2017-04-01

    Full Text Available The problem of the environment is a strategic challenge in the era we are living in. In this sense, more and more managers from various areas of activity, the tourism industry included, have become increasingly concerned of promoting better environmental practices. If these practices were based on the 3R’s principle, later on they developed amounting to the implementation of much more complex systems and strategies to support the solving of environmental problems. The paper highlights the main environmental strategies implemented in the hotels of Romania and Italy, presented in a comparative analysis. The study provides an image of the current situation in two regions of Romania and Italy, thus showing the efforts made by managers to ameliorate the impact of the activities carried out on the environment.

  7. Succession Planning: A Necessary Strategy for Rural School Administration.

    Science.gov (United States)

    Wallin, Dawn C.

    2001-01-01

    Succession planning focuses on anticipated future administrative positions, the expected skill requirements of those positions, and developing potential candidates to fill the positions. Although succession planning is basically a business oriented model, it seems appropriate for rural educational settings. Strategies for implementing succession…

  8. Blood volume measurement with indocyanine green pulse spectrophotometry: dose and site of dye administration

    NARCIS (Netherlands)

    M.R. Germans; P.C. de Witt Hamer; L.J. van Boven; K.A.H. Zwinderman; G.J. Bouma

    2010-01-01

    (1) To determine the optimal administration site and dose of indocyanine green (ICG) for blood volume measurement using pulse spectrophotometry, (2) to assess the variation in repeated blood volume measurements for patients after subarachnoid hemorrhage and (3) to evaluate the safety and efficacy of

  9. Financial Strategies for the Romanian Local Public Administration

    Directory of Open Access Journals (Sweden)

    Attila GYÖRGY

    2011-02-01

    Full Text Available Public administration reform at all governmental levels constitutes an important component of the transformation process from a centralized system to democratic governance. This process involved important legislative and institutional changes in order to fulfill the principles of a market economy and the European Union standards based on transparency, predictability, accountability, adaptability and effectiveness. Therefore, in a continuing extension of the citizens’ needs, Romanian public administration reform, especially at local level, is concentrated on quality of public services based on citizens’ needs and increased performances in the context of a necessary decrease of budget expenditure, taking into consideration the actual financial constraint. In this context, it is useful to investigate the financial strategies of the local public administration based on the Romanian experiences that consisted in important public resources decline because of the financial crisis.

  10. A Theoretical Strategy to Generate an Isolated 80-Attosecond Pulse

    Institute of Scientific and Technical Information of China (English)

    GUO Fu-Ming; YANG Yu-Jun; JIN Ming-Xing; DING Da-Jun; ZHU Qi-Ren

    2009-01-01

    Using a linearly polarized, phase-stabilized 2.66-femtcsecond driving pulse of 400 nm central wavelength orthogonally combined with another linearly polarized long pulse of 800nm central wavelength irradiating jointly on the helium atom, we demonstrate theoretically the generation of a clean isolated 80-attosecond pulse in the spectral region of 93-155 electron volts in a two-dimensional model.

  11. Teaching Ethics and Values in Public Administration Programs: Innovations, Strategies, and Issues. SUNY Series in Public Administration.

    Science.gov (United States)

    Bowman, James, Ed.; Menzel, Donald, Ed.

    The 17 chapters in this book consider innovations, teaching strategies, and issues in ethics instruction for professional and graduate programs in public affairs/administration. Following an introductory chapter which summarizes data reported in a 1995 national survey of 138 graduate departments of public affairs/administration, chapter titles…

  12. Vote Centers as a Strategy to Control Election Administration Costs

    Directory of Open Access Journals (Sweden)

    David H. Folz

    2014-03-01

    Full Text Available The rising costs of election administration in an era of fiscal stress have motivated some local officials to test the feasibility of ideas for reducing election costs while enhancing voter convenience and perhaps even increasing voter turnout. One such pilot project in a suburban community in the South involved replacing precinct-based voting on election day with a vote center that all voters could use regardless of their precinct of residence. A comparison of election costs across two municipal elections showed that replacing precinct-based voting with an election day vote center resulted in substantial cost savings. While there was no statistical difference in voter turnout in municipal elections held before and after implementation of the pilot project, voters were highly satisfied with the convenience of the vote center as well as other aspects of their voting experience. The findings suggest that an election day vote center can be a viable strategy to control election costs and enhance voters’ perceptions of the convenience of voting.

  13. Pulsed Power Science and Technology: A Strategic Outlook for the National Nuclear Security Administration (Summary)

    Energy Technology Data Exchange (ETDEWEB)

    Sinars, Daniel [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Scott, Kimberly Carole [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Edwards, M. John [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Olson, Russell Teall [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-10-17

    Major advances in pulsed power technology and applications over the last twenty years have expanded the mission areas for pulsed power and created compelling new opportunities for the Stockpile Stewardship Program (SSP). This summary document is a forward look at the development of pulsed power science and technology (PPS&T) capabilities in support of the next 20 years of the SSP. This outlook was developed during a three-month-long tri-lab study on the future of PPS&T research and capabilities in support of applications to: (1) Dynamic Materials, (2) Thermonuclear Burn Physics and Inertial Confinement Fusion (ICF), and (3) Radiation Effects and Nuclear Survivability. It also considers necessary associated developments in next-generation codes and pulsed power technology as well as opportunities for academic, industry, and international engagement. The document identifies both imperatives and opportunities to address future SSP mission needs. This study was commissioned by the National Nuclear Security Administration (NNSA). A copy of the memo request is contained in the Appendix. NNSA guidance received during this study explicitly directed that it not be constrained by resource limitations and not attempt to prioritize its findings against plans and priorities in other areas of the national weapons program. That prioritization, including the relative balance amongst the three focus areas themselves, must of course occur before any action is taken on the observations presented herein. This unclassified summary document presents the principal imperatives and opportunities identified in each mission and supporting area during this study. Preceding this area-specific outlook, we discuss a cross-cutting opportunity to increase the shot capacity on the Z pulsed power facility as a near-term, cost-effective way to broadly impact PPS&T for SSP as well as advancing the science and technology to inform future SSMP milestones over the next 5-10 years. The final page of the

  14. Pulsed Power Science and Technology: A Strategic Outlook for the National Nuclear Security Administration (Summary)

    Energy Technology Data Exchange (ETDEWEB)

    Sinars, Daniel [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Scott, Kimberly Carole [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Edwards, M. John [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Olson, Russell Teall [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-10-17

    Major advances in pulsed power technology and applications over the last twenty years have expanded the mission areas for pulsed power and created compelling new opportunities for the Stockpile Stewardship Program (SSP). This summary document is a forward look at the development of pulsed power science and technology (PPS&T) capabilities in support of the next 20 years of the SSP. This outlook was developed during a three month long tri-lab study on the future of PPS&T research and capabilities in support of applications to: (1) Dynamic Materials, (2) Thermonuclear Burn Physics and Inertial Confinement Fusion (ICF), and (3) Radiation Effects and Nuclear Survivability. It also considers necessary associated developments in next-generation codes and pulsed power technology as well as opportunities for academic, industry, and international engagement. The document identifies both imperatives and opportunities to address future SSP mission needs. This study was commissioned by the National Nuclear Security Administration (NNSA). A copy of the memo request is contained in the Appendix. NNSA guidance received during this study explicitly directed that it not be constrained by resource limitations and not attempt to prioritize its findings against plans and priorities in other areas of the national weapons program. That prioritization, including the relative balance amongst the three focus areas themselves, must of course occur before any action is taken on the observations presented herein. This unclassified summary document presents the principal imperatives and opportunities identified in each mission and supporting area during this study. Proceeding this area-specific outlook, we discuss a cross-cutting opportunity to increase the shot capacity on the Z pulsed power facility as a near term, cost effective way to broadly impact PPS&T for SSP as well as advancing the science and technology to inform future SSMP milestones over the next 5-10 years. The final page of the

  15. An Analysis to Strategy of Pulse Research in Iran Based Upon the First National Pulse Symposium Approaches

    Directory of Open Access Journals (Sweden)

    abdolreza bagheri

    2009-06-01

    Full Text Available Pulse, as the second source of human nutrition, benefits from great agronomic and nutritious features. These plants are amongst the most important crops which are full of protein and are widely cultivated all over the world; having the ability to adapt to different climate measures ranging from mild to hot and from moist to very dry. The other noteworthy trait of these crops is their talent to coexist with nitrogen fixation bacteria available in the soil which plays an important role in soil fertility and sustainability. For the previously mentioned reasons and many more, pulses have been extensive fields of research. With the substitution of legumes with fallow in the wheat-fallow agricultural system, great success in product stability has been gained. Having emphasized on the importance of the issue, the first national pulse symposium with the aim of investigating the opportunities and threats facing the development of pulse in Iran was held on 20-21 Nov. 2005 in the Ferdowsi University of Mashhad at the Research Center of Plant Sciences in collaboration with many scientific, research and administrative institutions. This paper aims at sketching the overview of the strategic research direction in Iran by analyzing the published papers presented in this conference and will provide the key points mentioned in the final conference manifestation.

  16. Administrative Strategies for Successful Adoption of Computer Technology.

    Science.gov (United States)

    Aitken, Joan E.; Shedletsky, Leonard J.

    2001-01-01

    Suggests that offering online courses extends the reach of education to people who otherwise may be unable to complete courses. Gives administrators a perspective from the standpoint of professors who are not "techies," but have been involved in the infusion of technology. Proposes that administrators keep seven critical ideas before them while…

  17. Interactive Education in Public Administration (2): Strategies for Teachers

    Science.gov (United States)

    Brock, Jonathan; Alford, John

    2015-01-01

    The previous article ("Interactive education in public administration (1): The role of teaching 'objects'") described the benefits of "moving from behind the lectern" to engage in interactive teaching in public policy and administration, and the central role of "objects" in that process. But teaching…

  18. Pulse

    Science.gov (United States)

    ... resting for at least 10 minutes. Take the exercise heart rate while you are exercising. ... pulse rate can help determine if the person's heart is pumping. Pulse ... rate gives information about your fitness level and health.

  19. Combined Pulse Electroporation – A Novel Strategy for Highly Efficient Transfection of Human and Mouse Cells

    Science.gov (United States)

    Stroh, Thorsten; Erben, Ulrike; Kühl, Anja A.; Zeitz, Martin; Siegmund, Britta

    2010-01-01

    The type of a nucleic acid and the type of the cell to be transfected generally affect the efficiency of electroporation, the versatile method of choice for gene regulation studies or for recombinant protein expression. We here present a combined square pulse electroporation strategy to reproducibly and efficiently transfect eukaryotic cells. Cells suspended in a universal buffer system received an initial high voltage pulse that was continuously combined with a subsequent low voltage pulse with independently defined electric parameters of the effective field and the duration of each pulse. At comparable viable cell recoveries and transfection efficiencies of up to 95% of all cells, a wide variety of cells especially profited from this combined pulse strategy by high protein expression levels of individual cells after transfection. Long-term silencing of gene expression by transfected small interfering RNA was most likely due to the uptake of large nucleic acid amounts as shown by direct detection of fluorochromated small interfering RNA. The highly efficient combined pulse electroporation strategy enables for external regulation of the number of naked nucleic acid molecules taken up and can be easily adapted for cells considered difficult to transfect. PMID:20209146

  20. Combined pulse electroporation--a novel strategy for highly efficient transfection of human and mouse cells.

    Directory of Open Access Journals (Sweden)

    Thorsten Stroh

    Full Text Available The type of a nucleic acid and the type of the cell to be transfected generally affect the efficiency of electroporation, the versatile method of choice for gene regulation studies or for recombinant protein expression. We here present a combined square pulse electroporation strategy to reproducibly and efficiently transfect eukaryotic cells. Cells suspended in a universal buffer system received an initial high voltage pulse that was continuously combined with a subsequent low voltage pulse with independently defined electric parameters of the effective field and the duration of each pulse. At comparable viable cell recoveries and transfection efficiencies of up to 95% of all cells, a wide variety of cells especially profited from this combined pulse strategy by high protein expression levels of individual cells after transfection. Long-term silencing of gene expression by transfected small interfering RNA was most likely due to the uptake of large nucleic acid amounts as shown by direct detection of fluorochromated small interfering RNA. The highly efficient combined pulse electroporation strategy enables for external regulation of the number of naked nucleic acid molecules taken up and can be easily adapted for cells considered difficult to transfect.

  1. Analysis of Symmetrical Pulse Width Modulation Strategies for Matrix Converters

    DEFF Research Database (Denmark)

    Larsen, K.B.; Jorgensen, A.H.; Helle, Lars

    2002-01-01

    This paper presents a new and easy way to understand the derivation of the modulation functions for matrix converters. It is shown how the duty cycles can be calculated using techniques known from the back-to-back (B2B) voltage source inverter (VSI), thus making the subject accessible to people...... with prior knowledge in standard drives. A new modulation strategy is presented minimizing harmonic distortion compared to the standard double-sided space vector modulation for matrix converters. An improvement to an existing modulator is also presented where the proposed modification improves the harmonic...... performance. The strategies are compared both analytically and by the use of both simulations and measurements on a 12 kW matrix converter prototype.It is found that the proposed modulator has superior performance compared to modulators with equal switching frequencies and an equal number of switchings....

  2. A.C.T.I.V.E. Administrator's Guide: Organizational and Administrative Strategies.

    Science.gov (United States)

    Vodola, Thomas M.

    Presented is the administrative guide for Project ACTIVE (All Children Totally Involved Exercising) designed to assist school districts or agencies in training educators to organize, conduct, and evaluate individualized-personalized physical education programs for handicapped students, prekindergarten through high school. Chapter I provides the…

  3. A strategy for sampling on a sphere applied to 3D selective RF pulse design.

    Science.gov (United States)

    Wong, S T; Roos, M S

    1994-12-01

    Conventional constant angular velocity sampling of the surface of a sphere results in a higher sampling density near the two poles relative to the equatorial region. More samples, and hence longer sampling time, are required to achieve a given sampling density in the equatorial region when compared with uniform sampling. This paper presents a simple expression for a continuous sample path through a nearly uniform distribution of points on the surface of a sphere. Sampling of concentric spherical shells in k-space with the new strategy is used to design 3D selective inversion and spin-echo pulses. These new 3D selective pulses have been implemented and verified experimentally.

  4. Effects of combined therapy of orbital cobalt Irradiation and oral corticosteroid administration, and pulse therapy for Graves' ophthalmopathy

    Energy Technology Data Exchange (ETDEWEB)

    Shigemasa, Chiaki; Ueta, Yoshihiko; Taniguchi, Shinichi; Mitani, Yasuo; Urabe, Keita; Tanaka, Takashi; Yoshida, Akio; Mashiba, Hiroto

    1989-03-01

    This preliminary study was performed to investigate the efficacy of the combined therapy of orbital cobalt irradiation and oral prednisolone administration, and pulse therapy, for Graves' ophthalmopathy. The combined therapy was undergone according to procedure of Bartalena et al. (1983) in 5 patients. Excellent or good response to combined therapy were shown by 3 patients with short-standing ocular symptoms (3-4 months), but not by 2 patients with long-standing ocular symptoms (12-13 months). Pulse therapy was performed on 2 patients who showed no improvement from combined therapy, and on a patient who had acute onset of opthalmopathy. One gram of methylprednisolone sodium succinate was given intravenously daily for 3 successive days. This infusion procedure was repeated 3 to 4 times at intervals of 1 week. One of 2 patients who showed no improvement from combined therapy also had no response to pulse therapy. The other 2 patients showed a good response to pulse therapy and showed no relapse of ophthalmopathy for 10 and 8 months, respectively. These data emphasize the need for early immuno-suppressive therapy for Graves' ophthalmopathy. Pulse therapy may be employed in patients who show no response to other therapy method.

  5. [Physical projects atelier: strategy for physical resources administration learning on nursing].

    Science.gov (United States)

    Draganov, Patricia Bover; Sanna, Maria Cristina

    2011-09-01

    The success of learning involves adequate strategies. Those inspired on andragogy, which is the science of teaching adults, seem to be ideal for the nursing undergraduate subject "projects", with a focus on the administration of physical resources for nursing. This study reports teaching strategies that try to estimulate the acquisition of competences that make the nurse capable of a dialogue on projects with a multiprofessional team. The strategy involved a workshop composed by four stages: reading of projects, health assistance institute (HAI) attributions, notions on physical scaling strategies and development of a glossary. The strategy, proposed by a graduate student in the subject "Strategies to the teaching of Administration", was tested through practical application, evaluated and approved by graduate students and teachers. The conditions for its implementation are working with few students, availability of proper classrooms and equipment, and partnership with HAIs.

  6. CONTROL STRATEGY FOR ELECTROHYDRAULIC POSITION SERVO SYSTEM WITH GENERALIZED PULSE CODE MODULATION

    Institute of Scientific and Technical Information of China (English)

    LIU Rong; PAN Huachen; CHEN Ying

    2007-01-01

    A hybrid control strategy has been designed and developed for the electro-hydraulic position servo control system with generalized Pulse code modulation (GPCM), which is suitable for the area where the work condition is poor and a large flow rate is required. It is difficult to control the GPCM system because the system is discrete. With consideration of the stability and speediness of the GPCM position servo control system, a control strategy is developed through the theoretical and experimental analyses. The control strategy integrates the merits of Bang-Bang control, PID control and fuzzy control. With this hybrid control strategy, the electro hydraulic control system has good performances, and the servo control is carried out with GPCM through on-offvalves.

  7. Fit-For-Purpose Land Administration: Developing Country Specific Strategies for Implementation

    DEFF Research Database (Denmark)

    Enemark, Stig; McLaren, Robin

    2017-01-01

    administration; 4) Designing the country specific FFP spatial / legal / institutional frameworks; 5) Capacity development; 6) Country specific instruction manuals; and 7) Economic benefits analysis. Finally, the paper presents some experiences and reflections from a case study on implementing the FFP approach......This paper looks at implementing Fit-For-Purpose land administration solutions at county level. This will require a country specific strategy drawing from the recent GLTN publication on “Fit-For-Purpose Land Administration – Guiding Principles for Country Implementation”. The Fit...

  8. A Study on Determination of Strategy for Pulse Industry through SWOT and SOR Analyses in Mersin Province

    Directory of Open Access Journals (Sweden)

    Osman Uysal

    2014-06-01

    Full Text Available Pulse processing industry almost all located in Mersin province in Turkey. Strategic importance considered both national and international trade in terms of capital, domestic and foreign trade connections, knowledge and experience, pulse processing technology Mersin has an important position in the world. However, decline in pulse crops production in recet years, market fluctuations lead companies to import intensively and competitor countries have become major supplier. In the study, these developments in pulse production and trade in recent years, companies and also researchers opinions take into account to determine companies strengths, weaknesses, opportunities, and threats for SWOT analysis with the aim of offer sector-oriented strategies. Results of SWOT analysis were analyzed with SOR analysis. It is tried to develop strategies for development of pulse industry.

  9. Mathematical analysis of a Chlamydia epidemic model with pulse vaccination strategy.

    Science.gov (United States)

    Samanta, G P

    2015-03-01

    In this paper, we have considered a dynamical model of Chlamydia disease with varying total population size, bilinear incidence rate and pulse vaccination strategy. We have defined two positive numbers R₀ and (R₁≤ R₀). It is proved that there exists an infection-free periodic solution which is globally attractive if R₀ 1 The important mathematical findings for the dynamical behaviour of the Chlamydia disease model are also numerically verified using MATLAB. Finally epidemiological implications of our analytical findings are addressed critically.

  10. Administration

    DEFF Research Database (Denmark)

    Bogen handler om den praksis, vi kalder administration. Vi er i den offentlige sektor i Danmark hos kontorfolkene med deres sagsmapper, computere, telefoner,, lovsamlinger,, retningslinier og regneark. I bogen udfoldes en mangfoldighed af konkrete historier om det administrative arbejde fra...... forskellige områder i den offentlige sektor. Hensigten er at forstå den praksis og faglighed der knytter sig til det administrative arbejde...

  11. Dental Hygiene Entry-Level Program Administrators' Strategies for Overcoming Challenges of Distance Education

    Science.gov (United States)

    Buchanan, Bette A.

    2009-01-01

    The use of distance education by entry-level dental hygiene programs is increasing. The focus of this study was to determine the number of entry-level dental hygiene program administrators with experience developing and/or maintaining dental hygiene education by distance, the challenges encountered, and the strategies used to overcome the…

  12. Strategies, Protections and Mitigations for Electric Grid from Electromagnetic Pulse Effects

    Energy Technology Data Exchange (ETDEWEB)

    Foster, Rita Ann [Idaho National Lab. (INL), Idaho Falls, ID (United States); Frickey, Steven Jay [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-01-01

    The mission of DOE’s Office of Electricity Delivery and Energy Reliability (OE) is to lead national efforts to modernize the electricity delivery system, enhance the security and reliability of America’s energy infrastructure and facilitate recovery from disruptions to the energy supply. One of the threats OE is concerned about is a high-altitude electro-magnetic pulse (HEMP) from a nuclear explosion and eletro-magnetic pulse (EMP) or E1 pulse can be generated by EMP weapons. DOE-OE provides federal leadership and technical guidance in addressing electric grid issues. The Idaho National Laboratory (INL) was chosen to conduct the EMP study for DOE-OE due to its capabilities and experience in setting up EMP experiments on the electric grid and conducting vulnerability assessments and developing innovative technology to increase infrastructure resiliency. This report identifies known impacts to EMP threats, known mitigations and effectiveness of mitigations, potential cost of mitigation, areas for government and private partnerships in protecting the electric grid to EMP, and identifying gaps in our knowledge and protection strategies.

  13. Strategies, Protections and Mitigations for Electric Grid Affets from Electro-Magnetic Pulse

    Energy Technology Data Exchange (ETDEWEB)

    Foster, Rita Ann [Idaho National Lab. (INL), Idaho Falls, ID (United States); Frickey, Steven Jay [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-01-01

    The mission of DOE’s Office of Electricity Delivery and Energy Reliability (OE) is to lead national efforts to modernize the electricity delivery system, enhance the security and reliability of America’s energy infrastructure and facilitate recovery from disruptions to the energy supply. One of the threats OE is concerned about is a high-altitude electro-magnetic pulse (HEMP) from a nuclear explosion and eletro-magnetic pulse (EMP) or E1 pulse can be generated by EMP weapons. DOE-OE provides federal leadership and technical guidance in addressing electric grid issues. The Idaho National Laboratory (INL) was chosen to conduct the EMP study for DOE-OE due to its capabilities and experience in setting up EMP experiments on the electric grid and conducting vulnerability assessments and developing innovative technology to increase infrastructure resiliency. This report identifies known impacts to EMP threats, known mitigations and effectiveness of mitigations, potential cost of mitigation, areas for government and private partnerships in protecting the electric grid to EMP, and identifying gaps in our knowledge and protection strategies.

  14. Pulsed field magnetization strategies and the field poles composition in a bulk-type superconducting motor

    Science.gov (United States)

    Huang, Zhen; Ruiz, H. S.; Coombs, T. A.

    2017-03-01

    High temperature superconducting (HTS) bulks offer the potential of trapping and maintaining much higher magnetic loading level compared with the conventional permanent magnets used in rotary machines, although the effective magnetization of multiple HTS bulks with different relative orientations over the surface of cylindrical rotors creates new challenges. In this paper, we present the design and numerical validation of the Pulse Field Magnetization (PFM) strategy considered for the magnetization of the four-pole synchronous fully superconducting motor developed at the University of Cambridge. In a first instance, singular columns of up to five HTS bulks aligned over the height of the rotor were subjected to up to three magnetic pulses of 1.5 T peak, and the experimental results have been simulated by considering the electrical and thermal properties of the system in a 2D approach. The entire active surface of the rotor is covered by HTS bulks of approximately the same dimensions, resulting in an uneven distribution of pole areas with at least one of the poles formed by up to 3 columns of magnetized bulks, with relatively the same peaks of trapped magnetic field. Thus, in order to effectively use the entire area of the superconducting rotor, multiple pulsed fields per column have been applied under the same experimental conditions, what results in about three times larger magnetic pole areas but with an average drop on the peaks of trapped magnetic field of about 50%.

  15. Pulsed field magnetization strategies and the field poles composition in a bulk-type superconducting motor

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Zhen, E-mail: zhen.huang@sjtu.edu.cn [Academy of Information Technology and Electrical Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240 (China); Ruiz, H.S., E-mail: dr.harold.ruiz@le.ac.uk [Department of Engineering, University of Leicester, University Road, Leicester LE1 7RH (United Kingdom); Coombs, T.A., E-mail: tac1000@cam.ac.uk [Department of Engineering, University of Cambridge, 9 JJ Thomson Avenue, Cambridge CB3 0FA (United Kingdom)

    2017-03-15

    Highlights: • Different compositions of the magnetic poles have been obtained depending on the relative orientation of the magnetizing coil and the surfaces of the columns of bulks that conform a magnetic pole. • Two bidimensional models accounting for the electromagnetic response of the top and lateral cross sections of three columns of HTS bulks subjected to multiple pulsed magnetic fields have been created. • An extended PFM strategy has been proposed by considering the magnetization of at least three successive columns of HTS bulks per pole. In the extended PFM strategy the area of each one of the poles can be seen increased by a factor of 200%-400% - Abstract: High temperature superconducting (HTS) bulks offer the potential of trapping and maintaining much higher magnetic loading level compared with the conventional permanent magnets used in rotary machines, although the effective magnetization of multiple HTS bulks with different relative orientations over the surface of cylindrical rotors creates new challenges. In this paper, we present the design and numerical validation of the Pulse Field Magnetization (PFM) strategy considered for the magnetization of the four-pole synchronous fully superconducting motor developed at the University of Cambridge. In a first instance, singular columns of up to five HTS bulks aligned over the height of the rotor were subjected to up to three magnetic pulses of 1.5 T peak, and the experimental results have been simulated by considering the electrical and thermal properties of the system in a 2D approach. The entire active surface of the rotor is covered by HTS bulks of approximately the same dimensions, resulting in an uneven distribution of pole areas with at least one of the poles formed by up to 3 columns of magnetized bulks, with relatively the same peaks of trapped magnetic field. Thus, in order to effectively use the entire area of the superconducting rotor, multiple pulsed fields per column have been applied

  16. Space Vector Pulse Width Modulation Strategy for Single-Phase Three-Level CIC T-source Inverter

    DEFF Research Database (Denmark)

    Shults, Tatiana E.; Husev, Oleksandr O.; Blaabjerg, Frede

    2016-01-01

    This paper presents a novel space vector pulse-width modulation strategy for a single-phase three-level buck-boost inverter based on an impedance-source network. The case study system is based on T-source inverter with continuous input current. To demonstrate the improved performance of the inver......This paper presents a novel space vector pulse-width modulation strategy for a single-phase three-level buck-boost inverter based on an impedance-source network. The case study system is based on T-source inverter with continuous input current. To demonstrate the improved performance...... of the inverter, the strategy was compared the traditional pulse-width modulation. It is shown that the approach proposed has fewer switching states and does not suffer from neutral point misbalance....

  17. Correction factor based double model fuzzy logic control strategy of arc voltage in pulsed MIG welding

    Institute of Scientific and Technical Information of China (English)

    Wu Kaiyuan; Huang Shisheng; Meng Yongmin

    2005-01-01

    According to the feature of arc voltage control in welding steel using pulsed MIG welding, a correction factor based double model fuzzy logic controller (FLC) was developed to realize the arc voltage control by means of arc voltage feedback.When the error of peak arc voltage was great, a coarse adjusting fuzzy logic control rules with correction factor was designed,in the controller, the peak arc voltage was controlled by the wire feeding speed by means of arc voltage feedback. When the error of peak arc voltage was small, a fine adjusting fuzzy logic control rules with correction factor was designed, in this controller, the peak arc voltage was controlled by the background time by means of arc voltage feedback. The FLC was realized in a Look-Up Table ( LUT) method. Experiments had been carried out aiming at implementing the control strategy to control the arc length change in welding process. Experimental results show that the controller proposed enables the consistency of arc length and the stabolity of arc voltage and welding process to be achieved in pulsed MIG welding process.

  18. Analysis of ventilator-associated pneumonia infection route by genome macrorestriction-pulsed-field gel electrophoresis and its prevention with combined nursing strategies.

    Science.gov (United States)

    Wang, Xiaodong; Wang, Junping; Li, Jing; Wang, Jing

    2014-12-01

    The aim of the present study was to explore the infection route of ventilator-associated pneumonia (VAP) and assess the effectiveness of a combined nursing strategy to prevent VAP in intensive care units. Bacteria from the gastric juice and drainage from the hypolarynx and lower respiratory tracts of patients with VAP were analyzed using genome macrorestriction-pulsed-field gel electrophoresis (GM-PFGE). A total of 124 patients with tracheal intubation were placed in the intervention group and were treated with a combined nursing strategy, comprising mosapride (gastric motility stimulant) administration and semi-reclining positioning. A total of 112 intubated patients were placed in the control group and received routine nursing care. The incidence rate of VAP, days of ventilation and mortality rate of patients were compared between the two groups. The GM-PFGE fingerprinting results of three strains of Pseudomonas aeruginosa from the gastric juice, subglottic secretion drainage and drainage of the lower respiratory tract in patients with VAP were similar across groups. The number of days spent on a ventilator by patients in the intervention group (7.37±5.32 days) was lower compared with that by patients in the control group (12.34±4.98 days) (Pnursing strategy (Pnursing strategy of gastric motility stimulant administration and the adoption of a semi-reclining position was effective in preventing VAP by reducing the occurrence of GER.

  19. Rekindling the spark. Five strategies to help healthcare administrators remain motivated when facing change.

    Science.gov (United States)

    Veninga, R L

    1992-11-01

    Many healthcare administrators find it difficult to stay renewed in their careers as pressure mounts on an already stressful work environment. Five strategies can rekindle the spark that once made a healthcare career so attractive. Sharply focused goals are the infrastructure of a harmonious work environment. When people progress toward achieving goals, dissatisfaction with their work environment decreases. Healthcare administrators must also find solutions to problems that chip away at happiness, such as chronic understaffing or a personality conflict with a colleague. If supervisors develop positive problem-solving attitudes, employees tend to emulate them. Administrators need to personalize their leadership style. If subordinates sense their administrator is involved in their occupational struggles, their loyalty will increase and their stress will decrease. A manager needs to be surrounded by creative, energized people because upbeat people have a way of renewing one's spirits. Meaningful friendships can provide support and a fresh perspective on problems. Finally, healthcare administrators must remain steadfastly hopeful even when budgets cast red ink and the future direction of healthcare is uncharted.

  20. A pulse coding and decoding strategy to perform Lamb wave inspections using simultaneously multiple actuators

    Science.gov (United States)

    De Marchi, Luca; Marzani, Alessandro; Moll, Jochen; Kudela, Paweł; Radzieński, Maciej; Ostachowicz, Wiesław

    2017-07-01

    The performance of Lamb wave based monitoring systems, both in terms of diagnosis time and data complexity, can be enhanced by increasing the number of transducers used to actuate simultaneously the guided waves in the inspected medium. However, in case of multiple simultaneously-operated actuators the interference among the excited wave modes within the acquired signals has to be considered for the further processing. To this aim, in this work a code division strategy based on the Warped Frequency Transform is presented. At first, the proposed procedure encodes actuation pulses using Gold sequences. Next, for each considered actuator the acquired signals are compensated from dispersion by cross correlating the warped version of the actuated and received signals. Compensated signals form the base for a final wavenumber imaging meant at emphasizing defects and or anomalies by removing incident wavefield and edge reflections. The proposed strategy is tested numerically, and validated through an experiment in which guided waves are actuated in a plate by four piezoelectric transducers operating simultaneously.

  1. Relationship between Community Drug Administration Strategy and Changes in Trachoma Prevalence, 2007 to 2013.

    Directory of Open Access Journals (Sweden)

    Bette Liu

    2016-07-01

    Full Text Available Australia is the only high income country with persisting endemic trachoma. A national control program involving mass drug administration with oral azithromycin, in place since 2006, has some characteristics which differ from programs in low income settings, particularly in regard to the use of a wider range of treatment strategies, and more regular assessments of community prevalence. We aimed to examine the association between treatment strategies and trachoma prevalence.Through the national surveillance program, annual data from 2007-2013 were collected on trachoma prevalence and treatment with oral azithromycin in children aged 5-9 years from three Australian regions with endemic trachoma. Communities were classified for each year according to one of four trachoma treatment strategies implemented (no treatment, active cases only, household and community-wide. We estimated the change in trachoma prevalence between sequential pairs of years and across multiple years according to treatment strategy using random-effects meta-analyses.Over the study period, 182 unique remote Aboriginal communities had 881 annual records of both trachoma prevalence and treatment. From the analysis of pairs of years, the greatest annual fall in trachoma prevalence was in communities implementing community-wide strategies, with yearly absolute reductions ranging from -8% (95%CI -17% to 1% to -31% (-26% to -37%; these communities also had the highest baseline trachoma prevalence (15.4%-43.9%. Restricting analyses to communities with moderate trachoma prevalence (5-19% at initial measurement, and comparing community trachoma prevalence from the first to the last year of available data for the community, both community-wide and more targeted treatment strategies were associated with similar absolute reductions (-11% [-8% to -13%] and -7% [-5% to -10%] respectively. Results were similar stratified by region.Consistent with previous research, community

  2. Medical library downsizing administrative, professional, and personal strategies for coping with change

    CERN Document Server

    Schott, Michael

    2005-01-01

    Learn how to stay ahead of the game when budgets and staff are cut Medical Library Downsizing: Administrative, Professional, and Personal Strategies for Coping with Change explores corporate downsizing and other company-wide events as they relate to medical librarians in their organization. This training manual is designed to help librarians prepare for a new era where shrinking budgets, inflated journal costs, and the increasing demand for new and expensive services now put salaries and jobs at risk. While focused on health care issues, this book will appeal to a general library audience and

  3. Experiences with Lean Six Sigma as improvement strategy to reduce parenteral medication administration errors and associated potential risk of harm.

    Science.gov (United States)

    van de Plas, Afke; Slikkerveer, Mariëlle; Hoen, Saskia; Schrijnemakers, Rick; Driessen, Johanna; de Vries, Frank; van den Bemt, Patricia

    2017-01-01

    In this controlled before-after study the effect of improvements, derived from Lean Six Sigma strategy, on parenteral medication administration errors and the potential risk of harm was determined. During baseline measurement, on control versus intervention ward, at least one administration error occurred in 14 (74%) and 6 (46%) administrations with potential risk of harm in 6 (32%) and 1 (8%) administrations. Most administration errors with high potential risk of harm occurred in bolus injections: 8 (57%) versus 2 (67%) bolus injections were injected too fast with a potential risk of harm in 6 (43%) and 1 (33%) bolus injections on control and intervention ward. Implemented improvement strategies, based on major causes of too fast administration of bolus injections, were: Substitution of bolus injections by infusions, education, availability of administration information and drug round tabards. Post intervention, on the control ward in 76 (76%) administrations at least one error was made (RR 1.03; CI95:0.77-1.38), with a potential risk of harm in 14 (14%) administrations (RR 0.45; CI95:0.20-1.02). In 40 (68%) administrations on the intervention ward at least one error occurred (RR 1.47; CI95:0.80-2.71) but no administrations were associated with a potential risk of harm. A shift in wrong duration administration errors from bolus injections to infusions, with a reduction of potential risk of harm, seems to have occurred on the intervention ward. Although data are insufficient to prove an effect, Lean Six Sigma was experienced as a suitable strategy to select tailored improvements. Further studies are required to prove the effect of the strategy on parenteral medication administration errors.

  4. [Regulation of hypnosis in Propofol anesthesia administration based on non-linear control strategy].

    Science.gov (United States)

    Ilyas, Muhammad; Khaqan, Ali; Iqbal, Jamshed; Riaz, Raja Ali

    Continuous adjustment of Propofol in manual delivery of anesthesia for conducting a surgical procedure overburdens the workload of an anesthetist who is working in a multi-tasking scenario. Going beyond manual administration and Target Controlled Infusion, closed-loop control of Propofol infusion has the potential to offer several benefits in terms of handling perturbations and reducing the effect of inter-patient variability. This paper proposes a closed-loop automated drug administration approach to control Depth Of Hypnosis in anesthesia. In contrast with most of the existing research on anesthesia control which makes use of linear control strategies or their improved variants, the novelty of the present research lies in applying robust control strategy i.e. Sliding Mode Control to accurately control drug infusion. Based on the derived patient's model, the designed controller uses measurements from EEG to regulate DOH on Bispectral Index by controlling infusion rate of Propofol. The performance of the controller is investigated and characterized with real dataset of 8 patients undergoing surgery. Results of this in silico study indicate that for all the patients, with 0% overshoot observed, the steady state error lies in between ±5. Clinically, this implies that in all the cases, without any overdose, the controller maintains the desired DOH level for smooth conduction of surgical procedures. Copyright © 2016 Sociedade Brasileira de Anestesiologia. Publicado por Elsevier Editora Ltda. All rights reserved.

  5. Regulation of hypnosis in Propofol anesthesia administration based on non-linear control strategy.

    Science.gov (United States)

    Ilyas, Muhammad; Khaqan, Ali; Iqbal, Jamshed; Riaz, Raja Ali

    Continuous adjustment of Propofol in manual delivery of anesthesia for conducting a surgical procedure overburdens the workload of an anesthetist who is working in a multi-tasking scenario. Going beyond manual administration and Target Controlled Infusion, closed-loop control of Propofol infusion has the potential to offer several benefits in terms of handling perturbations and reducing the effect of inter-patient variability. This paper proposes a closed-loop automated drug administration approach to control Depth Of Hypnosis in anesthesia. In contrast with most of the existing research on anesthesia control which makes use of linear control strategies or their improved variants, the novelty of the present research lies in applying robust control strategy i.e. Sliding Mode Control to accurately control drug infusion. Based on the derived patient's model, the designed controller uses measurements from EEG to regulate DOH on Bispectral Index by controlling infusion rate of Propofol. The performance of the controller is investigated and characterized with real dataset of 8 patients undergoing surgery. Results of this in silico study indicate that for all the patients, with 0% overshoot observed, the steady state error lies in between ±5. Clinically, this implies that in all the cases, without any overdose, the controller maintains the desired DOH level for smooth conduction of surgical procedures. Copyright © 2016 Sociedade Brasileira de Anestesiologia. Published by Elsevier Editora Ltda. All rights reserved.

  6. New strategy of tacrolimus administration in animal model based on tacrolimus-loaded microspheres.

    Science.gov (United States)

    Zamorano-Leon, Jose J; Hernandez-Fisac, Ines; Guerrero, Sandra; Tamarit-Rodriguez, Jorge; Santos-Sancho, Juana M; Sopeña, Bernardo; Escolar, Ginés; López-Vilchez, Irene; Duarte, Juan; Barrientos, Alberto; López-Farré, Antonio J

    2016-05-01

    New strategies for tacrolimus administration that conserve its immunosuppressive effect but avoiding fluctuations in tacrolimus circulating levels are needed. The aim was to analyze if subcutaneous biodegradable tacrolimus-loaded microspheres injection promoted a significant immunosuppressive response in rats. Rats received two subcutaneous tacrolimus-loaded microspheres injections at different days, the first injection was done at day 0 and the second injection was done 12 days after. Plasma circulating levels of tacrolimus, interleukin-2 (IL-2) and calcineurin phosphatase (PP2B) activity in mononuclear cells were measured. Tacrolimus plasma levels were significantly increased from the day after tacrolimus-loaded microspheres injection and remained increased during 10days. Compared to control, plasma IL-2 levels and PP2B activity in mononuclear cells were significantly decreased during ten days. At day 12, a new subcutaneous injection of tacrolimus-loaded microspheres was performed and two days after injection, tacrolimus plasma levels were again increased and both IL-2 plasma levels and PP2B activity decreased. A single subcutaneous tacrolimus-loaded microspheres injection was enough to reduce tacrolimus-related immunosuppressive parameters. These results open the possibility of new therapeutic strategies to administrate calcineurin inhibitors reducing the variability of their circulating levels related to gastrointestinal drug absorption/metabolism modifications.

  7. Regulation of hypnosis in Propofol anesthesia administration based on non-linear control strategy

    Directory of Open Access Journals (Sweden)

    Muhammad Ilyas

    Full Text Available Abstract Continuous adjustment of Propofol in manual delivery of anesthesia for conducting a surgical procedure overburdens the workload of an anesthetist who is working in a multi-tasking scenario. Going beyond manual administration and Target Controlled Infusion, closed-loop control of Propofol infusion has the potential to offer several benefits in terms of handling perturbations and reducing the effect of inter-patient variability. This paper proposes a closed-loop automated drug administration approach to control Depth Of Hypnosis in anesthesia. In contrast with most of the existing research on anesthesia control which makes use of linear control strategies or their improved variants, the novelty of the present research lies in applying robust control strategy i.e. Sliding Mode Control to accurately control drug infusion. Based on the derived patient's model, the designed controller uses measurements from EEG to regulate DOH on Bispectral Index by controlling infusion rate of Propofol. The performance of the controller is investigated and characterized with real dataset of 8 patients undergoing surgery. Results of this in silico study indicate that for all the patients, with 0% overshoot observed, the steady state error lies in between ±5. Clinically, this implies that in all the cases, without any overdose, the controller maintains the desired DOH level for smooth conduction of surgical procedures.

  8. Speaking with forked tongues - Swedish public administration and the European employment strategy

    Directory of Open Access Journals (Sweden)

    Åsa Casula Vifell

    2009-07-01

    Full Text Available The aim of this paper is to understand how decision making processes within the EU comes to affect the structures for national policy making within the employment field. The paper addresses the question of how the process of writing new employment guidelines for the EES – European employment strategy, has affected the work of the Swedish public administration. Through applying a neo-institutionalist perspective, it contributes to the understanding of effects that the increased embededness of states, often characterized as Europeanization, invoke on national administrations. I argue that the way the process has been managed can be analyzed from an organizational perspective where conflicting demands on the Swedish state has led to a certain organization of the work activities. On the one hand, Swedish representatives have to act according to the norms of the European cooperation in order to be seen as a legitimate actor. On the other hand, EU and European influence on Swedish employment policy is not a legitimate concept at national level. In order to satisfy these two seemingly incompatible demands the organizing principle of decoupling is being used to create space for maneuvering for the administration. However, through participation at EU-level organizational identities are partly transformed which in time leads to a situation where changed practices are not met by changes in formal structures. As a consequence the Swedish representatives are in a manner ‘speaking with forked tongue’ and obscuring the new way in which policy making is conducted thus introducing democratic shortcomings in terms of transparency and accountability.

  9. Optimising strategies for Plasmodium falciparum malaria elimination in Cambodia: primaquine, mass drug administration and artemisinin resistance.

    Directory of Open Access Journals (Sweden)

    Richard J Maude

    Full Text Available BACKGROUND: Malaria elimination requires a variety of approaches individually optimized for different transmission settings. A recent field study in an area of low seasonal transmission in South West Cambodia demonstrated dramatic reductions in malaria parasite prevalence following both mass drug administration (MDA and high treatment coverage of symptomatic patients with artemisinin-piperaquine plus primaquine. This study employed multiple combined strategies and it was unclear what contribution each made to the reductions in malaria. METHOD AND FINDINGS: A mathematical model fitted to the trial results was used to assess the effects of the various components of these interventions, design optimal elimination strategies, and explore their interactions with artemisinin resistance, which has recently been discovered in Western Cambodia. The modelling indicated that most of the initial reduction of P. falciparum malaria resulted from MDA with artemisinin-piperaquine. The subsequent continued decline and near elimination resulted mainly from high coverage with artemisinin-piperaquine treatment. Both these strategies were more effective with the addition of primaquine. MDA with artemisinin combination therapy (ACT increased the proportion of artemisinin resistant infections, although much less than treatment of symptomatic cases with ACT, and this increase was slowed by adding primaquine. Artemisinin resistance reduced the effectiveness of interventions using ACT when the prevalence of resistance was very high. The main results were robust to assumptions about primaquine action, and immunity. CONCLUSIONS: The key messages of these modelling results for policy makers were: high coverage with ACT treatment can produce a long-term reduction in malaria whereas the impact of MDA is generally only short-term; primaquine enhances the effect of ACT in eliminating malaria and reduces the increase in proportion of artemisinin resistant infections; parasite

  10. A pulse-chase strategy for EdU labelling assay is able to rapidly quantify cell division orientation.

    Science.gov (United States)

    Yin, Xiaofeng; Tsukaya, Hirokazu

    2016-09-01

    Measurement of the direction of cell division is an important, yet difficult, task to analyse how a plant organ acquires its final shape from an initially small group of cells. We introduce a method that rapidly and easily quantifies cell division direction and is applicable to all plant species. A pulse-chase strategy for 5-ethynyl-2'-deoxyuridine (EdU) labelling assay was established and was shown to be successful for leaves of Arabidopsis thaliana (Arabidopsis) and Juncus prismatocarpus. By optimization of the pulse and chase periods, most of the signals obtained were sets of daughter nuclei. For Arabidopsis, the optimal time was a 45-min pulse and a 7-h chase. For J. prismatocarpus, the optimal time was a 2-h pulse and a 13.5-h chase. The positions of the daughter nuclei were used to quantify cell division direction in the Arabidopsis leaf primordia. Overall, cell division along the proximal-distal axis was more frequent than along the medial-lateral axis. In petiole, major vein, minor vein and margin areas, the major cell division direction seemed to be coincident with the direction of auxin flow. The advantages of our method over the few methods used previously are discussed. We anticipate that it will provide opportunities to study plant development in the near future.

  11. Multi-frequency accelerating strategy for the contrast source inversion method of ultrasound waveform tomography using pulse data

    Science.gov (United States)

    Lin, Hongxiang; Azuma, Takashi; Qu, Xiaolei; Takagi, Shu

    2017-03-01

    In this work, we construct a multi-frequency accelerating strategy for the contrast source inversion (CSI) method using pulse data in the time domain. CSI is a frequency-domain inversion method for ultrasound waveform tomography that does not require the forward solver through the process of reconstruction. Several prior researches show that the CSI method has a good performance of convergence and accuracy in the low-center-frequency situation. In contrast, utilizing the high-center-frequency data leads to a high-resolution reconstruction but slow convergence on large numbers of grid. Our objective is to take full advantage of all low frequency components from pulse data with the high-center-frequency data measured by the diagnostic device. First we process the raw data in the frequency domain. Then multi-frequency accelerating strategy helps restart CSI in the current frequency using the last iteration result obtained from the lower frequency component. The merit of multi- frequency accelerating strategy is that computational burden decreases at the first few iterations. Because the low frequency component of dataset computes on the coarse grid with assuming a fixed number of points per wavelength. In the numerical test, the pulse data were generated by the K-wave simulator and have been processed to meet the computation of the CSI method. We investigate the performance of the multi-frequency and single-frequency reconstructions and conclude that the multi-frequency accelerating strategy significantly enhances the quality of the reconstructed image and simultaneously reduces the average computational time for any iteration step.

  12. Institutional Level Identity Control Strategies in the Distance Education Environment: A Survey of Administrative Staff

    Directory of Open Access Journals (Sweden)

    Alexander Amigud

    2013-12-01

    Full Text Available Physical separation of students and instructors creates the gap of anonymity and limited control over the remote learning environment. The ability of academic institutions to authenticate students and validate authorship of academic work at various points during a course is necessary for preserving not only perceived credibility but also public safety. With the growing scope of distance education programs that permeate critical areas such as healthcare, airspace, water management, and food solutions, universities have a moral obligation to employ secure measures to verify learning outcomes. This study examines the measures universities with large distance education programs employ to align identity of learners with the academic work they do, as well as the effectiveness of and challenges and barriers to their implementation. The research was undertaken using a multiple case approach and examined survey responses from five academic administrators at five officially accredited post secondary institutions in three countries. The cases examined in the study include: Athabasca University, Open University UK, Penn State University World Campus, University of Maryland University College, and eConcordia, Concordia University’s distance learning facility. This study is not an exhaustive attempt to examine all aspects of academic integrity, but rather to create awareness about various learner authentication strategies. This study confirms that secure learner authentication in the distance education environment is possible. However, with greater pressure to enhance security of learner authentication, the openness of open learning is challenged and may change as we know it.

  13. 45 CFR 1336.64 - Development of goals and strategies: Responsibilities of the Loan Administrator.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Development of goals and strategies... Loan Fund Demonstration Project § 1336.64 Development of goals and strategies: Responsibilities of the... the basis for the development of an organizational strategy and operating plan. The RLF strategies...

  14. Taking local optics outreach abroad for IYL 2015: administrative and logistical challenges and strategies

    Science.gov (United States)

    Wong, Nicholas H. L.; Posner, Matthew T.; Mittal, Vinita; Gray, David R.; John, Pearl V.

    2016-09-01

    The Lightwave Roadshow is an outreach program run by research students at the University of Southampton, UK, that seeks to educate and inspire young students with optics, through conducting workshops in local schools and exhibiting at local and regional educational fairs. Adopting a hands-on philosophy enabled by an extensive collection of experimental optical demonstrations, Lightwave aims to promote scientific interest and indirectly address the global STEM skills shortage. While Lightwave has become a well-established program in local schools since its inception in 1998, 2015 included an unprecedented number of overseas activities. Inspired by the In- ternational Year of Light and Light-based Technologies (IYL 2015), Lightwave organized a school workshop in a foreign country (Singapore) as well as exhibited at major events, including the IYL 2015 opening ceremony in France, which marked the first time that the roadshow used UK school students to deliver outreach activities beyond the UK. These recent successful overseas projects have encouraged the outreach team to continue expand- ing the reach of the roadshow internationally. Of particular note is the involvement of Lightwave at academic conferences, where experiences and best practices can be shared among outreach ambassadors from different programs, student chapters, universities, and organizations. This paper provides a review of these activities, and identifies the administrative and practical challenges of bringing a local outreach program abroad and some strategies to overcome them. We also outline our travel suite of experimental demonstration kit, a portable selection from our main equipment inventory. This won the recent OSA `IYL-To-Go' student competition.

  15. An Empirical Analysis of Government Administrative Strategy: From the Governance, Competence and Relationship Perspectives

    National Research Council Canada - National Science Library

    Chiou Chi-Ho

    2013-01-01

      Employing the governance, competence and relationship perspectives, this article discusses what factors will enhance a government's administrative efficiency and effectiveness, and how to improve...

  16. Independent Planning System and Public Administration in Metropolitan Development: Agglomeration Strategies of Greater Chaoshan in Southern China

    Directory of Open Access Journals (Sweden)

    Tian Guang

    2017-04-01

    Full Text Available This paper examines independent planning system as a means of public administration in regional economic development. It proposes a new strategy based on the theories of public administrative resources, to agglomerate and unify the cities of Shantou, Jieyang, and Chaozhou into a new administrative entity as a metropolis with the status of independent planning and the preferred policies of a Special Economic Region to lead regional development. The optimal allocation of public administrative resources has played a key role in the fundamental economic development in China in recent years. The new administrative system of large cities (metropolises with independent planning has become an innovative format to utilize the renewable soft resources of administration, which in fact is a new attempt to reform the economic system by the Chinese government. The greater Chaoshan area needs to be agglomerated and unified to further develop the regional economy with the implementation of independent planning system. The current research conducted from a practical and political point of view is of significant value to the overall planning and strategic layout of the economic and social development of the whole eastern Guangdong region.

  17. Psychological Research With Administrative Data Sets: An Underutilized Strategy for Mental Health Services Research.

    Science.gov (United States)

    Walkup, James T; Yanos, Philip T

    2005-10-01

    A key element in the identity of professional psychologists is their commitment to base practice on the best knowledge available about a problem being tackled. Although administrative data (e.g., records of provider billing and procedures) can often shed light on the dark areas of the complex U.S. health care system, psychologists make notably little use of them. Experience teaches that decisions must often be made despite the absence of "gold standard" knowledge from the well-designed, controlled studies learned in graduate school. Increased involvement of psychologists in work using administrative data can improve service provision but requires that psychologists adopt unaccustomed approaches to research. The authors discuss administrative data's strengths and limitations, recent progress made in using them, how psychologists can acquire and use low-cost information from administrative data, and examples of questions that can be answered.

  18. Effect of Dietary Administration of Lathyrus sativus Pulse on Intestinal Biochemical Parameters in Normal and Scorbutic Guinea Pigs

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Objective In order to investigate that ascorbic acid deficiency is responcible for lathyrus toxicity, the effect of dietary feeding of lathyrus pulse in normal and scorbutic guinea pigs for 3 months, on intestinal biochemical parameters was undertaken. Methods The intestinal brush border membrane (BBM) marker and xenobiotic metabolising enzymes (XME) were assayed. Results Exposure to 80% lathyrus alone and in scorbutic conditions showed significant inhibition of alkaline phosphatase (28%-30%), sucrase (19%) and γ-glutamyl transpeptidasc (GGT) (15%-27%)enzymes, while Ca2+-Mg2+-ATPase was significantly inhibited (38%) in scorbutic plus lathyrus treated group. The phase Ⅰ XME (AHH) remained unchanged while the phase Ⅱ enzyme glutathioneS-tranferase (GST) was significantly decreased (20%-22%) in lathyrus and scorbutic plus lathyrus treated groups. Quinone reductase (QR) activity was found to be significantly decreased in lathyrus exposed group (20%). The intestinal biomarker contents including hexose (25%-34%) and phospholipids (20%-40%) were significantly reduced in lathyrus and scorbutic plus lathyrus exposed animals, while sialic acid showed a significant decrease (28%) in scorbutic plus lathyrus treated group. However, cholesterol levels were signifcantly enhanced (15%-28%) in lathyrus and scorbutic plus lathyrus treated animals. Conclusion The results indicate that oral feeding of lathyrus pulse to guinea pigs can alter BBM parameters as well as XME, which may result in the intestinal toxicity.Further, ascorbic acid deficiency could be one of the pre-disposing factors of lathyrus toxicity.

  19. Global Strategy Implementation at the Business Unit Level: Operational Capabilities and Administrative Mechanisms

    OpenAIRE

    Kendall Roth; David M Schweiger; Allen J Morrison

    1991-01-01

    The study examines the impact of internationally strategy on organizational design and the influence of the organizational design on effectiveness at the business unit level. The empirical findings are based on survey responses from eighty-two business units competing in global industries. The findings are supportive of the contingency notion which suggests that business unit effectiveness is a function of the fit between the international strategy and the organizational design.© 1991 JIBS. J...

  20. Global Strategy Implementation at the Business Unit Level: Operational Capabilities and Administrative Mechanisms

    OpenAIRE

    Kendall Roth; David M Schweiger; Allen J Morrison

    1991-01-01

    The study examines the impact of internationally strategy on organizational design and the influence of the organizational design on effectiveness at the business unit level. The empirical findings are based on survey responses from eighty-two business units competing in global industries. The findings are supportive of the contingency notion which suggests that business unit effectiveness is a function of the fit between the international strategy and the organizational design.© 1991 JIBS. J...

  1. Low-intensity pulsed ultrasound therapy: a potential strategy to stimulate tendon-bone junction healing

    Institute of Scientific and Technical Information of China (English)

    Zhi-min YING; Tiao LIN; Shi-gui YAN

    2012-01-01

    Incorporation of a tendon graft within the bone tunnel represents a challenging clinical problem.Successful anterior cruciate ligament (ACL) reconstruction requires solid healing of the tendon graft in the bone tunnel.Enhancement of graft healing to bone is important to facilitate early aggressive rehabilitation and a rapid return to pre-injury activity levels.No convenient,effective or inexpensive procedures exist to enhance tendon-bone (T-B) healing after surgery.Low-intensity pulsed ultrasound (LIPUS) improves local blood perfusion and angiogenesis,stimulates cartilage maturation,enhances differentiation and proliferation of osteoblasts,and motivates osteogenic differentiation of mesenchymal stem cells (MSCs),and therefore,appears to be a potential non-invasive tool for T-B healing in early stage of rehabilitation of ACL reconstruction.It is conceivable that LIPUS could be used to stimulate T-B tunnel healing in the home,with the aim of accelerating rehabilitation and an earlier return to normal activities in the near future.The purpose of this review is to demonstrate how LIPUS stimulates T-B healing at the cellular and molecular levels,describe studies in animal models,and provide a future direction for research.

  2. An administrative marketing strategy: a different perspective on the nursing process.

    Science.gov (United States)

    Beaupre, B A

    1988-11-01

    Through the methods of the nursing process, nurse administrators were able to sell nursing to nurses. The use of marketing to link the business world with nursing stimulated professional dedication, skill, and responsibility. The program helped to encourage habits of flexibility, ensure continuous learning, acceptance of change, and the opportunity for individuals and institutions to grow and advance. It promoted autonomous, collaborative, and consultative practice. Nurturing the nurse had become a reality.

  3. Online Search Strategies of Educational Administrators for Determining the Credibility of Information Gleaned from a Website

    Science.gov (United States)

    Morrison, James L.; Oladunjoye, Ganiyu T.; Rose, Dale

    2008-01-01

    Based on a survey of 158 educational leaders situated in public schools, the level of educational leadership, whether a school superintendent or a principal in a secondary, middle-school, or elementary school, was not a significant factor in operational online strategies utilized or benchmarks relied upon for determining the credibility of…

  4. Potential Effects of Teaching Strategies on Students' Academic Performance under a Trump Administration

    Science.gov (United States)

    Guirguis, Ruth; Pankowski, Jennifer

    2017-01-01

    The purpose of this meta-analysis was to explore in detail the research by Hattie (2009) in order to then re-examine it through a new lens and better understand the research and possible bias. For this study, the unit of analysis were the studies used in Hattie (2009). The criteria for inclusion were based on strategies currently implemented in…

  5. Mastering Leadership Concepts through Utilizing Critical Thinking Strategies within Educational Administration Courses at Kuwait University

    Science.gov (United States)

    Alqahtani, Abdulmuhsen Ayedh; Al-Enezi, Mutlaq M.

    2012-01-01

    The current study aims at exploring the students' perceptions of mastering leadership concepts and critical thinking strategies implemented by faculty members in the college of education at Kuwait University, and the impact of the later on former. The data was collected using a questionnaire on a sample consisting of 411 students representing…

  6. Administrative Challenges and Response Strategies to the Job Performance of Marketing Department Chairs.

    Science.gov (United States)

    Dyer, Beverly G.; Miller, Michael T.

    This study reports on the job challenges and corresponding response strategies that department chairs at graduate and undergraduate colleges and universities encounter and rely upon. Literature and research related to marketing department chairs, marketing education, and marketing majors indicates that business schools have come under attack by…

  7. An in vivo strategy to counteract post-administration anticoagulant activity of azido-Warfarin

    Science.gov (United States)

    Ursuegui, Sylvain; Recher, Marion; Krężel, Wojciech; Wagner, Alain

    2017-05-01

    Drugs, usually long acting and metabolically stable molecules, might be the source of adverse effects triggered by complex drug interactions, anaphylaxis and drug-induced coagulopathy. To circumvent this growing drug safety issue, we herein investigate the opportunity offered by bio-orthogonal chemistry for in vivo drug neutralization. We design a small-molecule anticoagulant drug (Warfarin) containing an azide group that acts as a safety pin. It allows drug deactivation and restoration of physiological coagulation via in vivo click reaction with a suitable cyclooctyne-based neutralizing agent. In this strategy, the new molecule formed by reaction of the drug and the antidote is deprived of biological activity and prone to fast renal clearance. This `Click & Clear' approach lays ground for new strategies in designing drugs with switchable biophysical properties.

  8. Insulin administration: present strategies and future directions for a noninvasive (possibly more physiological delivery

    Directory of Open Access Journals (Sweden)

    Matteucci E

    2015-06-01

    Full Text Available Elena Matteucci,1 Ottavio Giampietro,1 Vera Covolan,2 Daniela Giustarini,3 Paolo Fanti,4 Ranieri Rossi3 1Department of Clinical and Experimental Medicine, 2Department of Chemistry and Industrial Chemistry, University of Pisa, 3Department of Life Sciences, Laboratory of Pharmacology and Toxicology, University of Siena, Siena, Italy; 4Division of Nephrology, University of Texas Health Science Center San Antonio, South Texas Veteran Health Care System, San Antonio, Texas, USA Abstract: Insulin is a life-saving medication for people with type 1 diabetes, but traditional insulin replacement therapy is based on multiple daily subcutaneous injections or continuous subcutaneous pump-regulated infusion. Nonphysiologic delivery of subcutaneous insulin implies a rapid and sustained increase in systemic insulin levels due to the loss of concentration gradient between portal and systemic circulations. In fact, the liver degrades about half of the endogenous insulin secreted by the pancreas into the venous portal system. The reverse insulin distribution has short- and long-term effects on glucose metabolism. Thus, researchers have explored less-invasive administration routes based on innovative pharmaceutical formulations, which preserve hormone stability and ensure the therapeutic effectiveness. This review examines some of the recent proposals from clinical and material chemistry point of view, giving particular attention to patients’ (and diabetologists’ ideal requirements that organic chemistry could meet. Keywords: type 1 diabetes mellitus, drug formulations, drug administration routes, insulin, portal system, nanoparticles, biodegradable polymers

  9. Empowered? Evaluating Japan's national energy strategy under the DPJ administration

    Energy Technology Data Exchange (ETDEWEB)

    Valentine, Scott, E-mail: valentine@pp.u-tokyo.ac.j [Graduate School of Public Policy (GraSPP), University of Tokyo, 620 Administration Bureau Building No. 2, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan); Sovacool, Benjamin K., E-mail: bsovacool@nus.edu.s [Lee Kuan Yew School of Public Policy, National University of Singapore, 02-03J Oei Tiong Ham Building, 469C Bukit Timah Road, Singapore 259772 (Singapore); Matsuura, Masahiro, E-mail: matsuura@pp.u-tokyo.ac.j [Graduate School of Public Policy (GraSPP), University of Tokyo, 620 Administration Bureau Building No. 2, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan)

    2011-03-15

    In August 2009, after 54 years of virtually unbroken rule, Japan's Liberal Democratic Party (LDP) was ousted from power by the Democratic Party of Japan (DPJ). The DPJ's campaign platform included a pledge to facilitate extreme reductions in greenhouse gas (GHG) emissions. Yet, at the COP16 meeting in Cancun, Japan announced that it would not accept further emission reduction targets without broader commitment from all nations. This paper seeks to explain this dichotomy by employing a targeted stakeholder evaluation based on surveys with 321 Japanese citizens to assess the extent to which influential stakeholder groups in Japan supports a potentially costly transition to a low-carbon energy infrastructure amidst severe economic challenges that the nation faces. Findings help explain Japan's adversarial role in COP16 negotiations in Cancun, despite the stated GHG reduction ambitions of Japan's current ruling party. The analysis concludes that if the DPJ does embrace aggressive CO{sub 2} reduction targets in the future, the strategic focus will likely mirror the former ruling party's energy policy of bolstering nuclear power generation capacity and promoting energy efficiency improvements while exhibiting lukewarm commitment to supporting capacity development in alternative sources of energy supply such as solar panels and wind turbines. - Research highlights: {yields} Public consensus exists regarding which energy policy goals are important in Japan. {yields} Minor perceptual differences are not of a catalytic nature. {yields} Public consensus does not deviate significantly from past LDP energy policy. {yields} Unlikely that the DPJ will pursue costly energy transition initiatives. {yields} Likely that the DPJ energy strategy will be substantively similar to LDP strategy. {yields} Any differences in strategy will focus on CO{sub 2} reduction magnitude not substance.

  10. Insulin administration: present strategies and future directions for a noninvasive (possibly more physiological) delivery

    Science.gov (United States)

    Matteucci, Elena; Giampietro, Ottavio; Covolan, Vera; Giustarini, Daniela; Fanti, Paolo; Rossi, Ranieri

    2015-01-01

    Insulin is a life-saving medication for people with type 1 diabetes, but traditional insulin replacement therapy is based on multiple daily subcutaneous injections or continuous subcutaneous pump-regulated infusion. Nonphysiologic delivery of subcutaneous insulin implies a rapid and sustained increase in systemic insulin levels due to the loss of concentration gradient between portal and systemic circulations. In fact, the liver degrades about half of the endogenous insulin secreted by the pancreas into the venous portal system. The reverse insulin distribution has short- and long-term effects on glucose metabolism. Thus, researchers have explored less-invasive administration routes based on innovative pharmaceutical formulations, which preserve hormone stability and ensure the therapeutic effectiveness. This review examines some of the recent proposals from clinical and material chemistry point of view, giving particular attention to patients’ (and diabetologists’) ideal requirements that organic chemistry could meet. PMID:26124635

  11. Acute administration of benzodiazepines as part of treatment strategies for epilepsy.

    Science.gov (United States)

    Wolf, Peter

    2011-08-01

    Ad-hoc administration of benzodiazepines (BZD) is well established in status epilepticus, but intermittent BZD use in the treatment of chronic epilepsy is little known beyond catamenial epilepsy. We aim to assess the use of acute drug administration (ADA) in the treatment of 24 patients with epilepsy (9 idiopathic generalized, 14 focal symptomatic/cryptogenic, 1 migraine-epilepsy) receiving ADA for (1) prevention of generalized tonic-clonic seizures (GTCS) after minor seizures, (2) prevention of seizures at perceived risk, (3) prevention of seizure clusters. Standard ADA was 10 mg oral clobazam (CLB); one patient received 10 mg rectal diazepam. Concomitant antiepileptic drugs (AED) remained unchanged whenever possible. Ten patients used ADA always correctly, 7 mostly, 7 sporadically or not. Outcome considering seizure control was positive in 44% of all patients (59% of those who actually used ADA): 5 patients seizure free, 1 free of disabling seizures, 4 with >50% reduction in seizure frequency. Eleven had minor or no improvement, 3 patients could not be rated. Thirteen (of 19 possible) patients attempted prevention of seizures or clusters, 10 with full or >50% success (52.6 resp. 76.9%). Prevention of clusters sometimes required higher or repetitive CLB dosing. Self rating of patients who did use ADA was positive or very positive in 88.2%. Retention rate was 66.7% of all patients, and 88.2% of those using ADA. The best results were obtained in idiopathic generalized epilepsy (IGE) patients with seizures habitually triggered by typical factors (sleep deprival, alcohol) but also some others were successful. The only adverse effect was gait ataxia in a multiple-handicapped patient. ADA is an elegant and often successful but underused treatment option for selected patient groups where it can make the difference between becoming seizure free or not. Depending on the individual case it can be applied as monotherapy or in combination with a basis AED. A controlled

  12. A frequency and pulse-width co-modulation strategy for transcutaneous neuromuscular electrical stimulation based on sEMG time-domain features

    Science.gov (United States)

    Zhou, Yu-Xuan; Wang, Hai-Peng; Bao, Xue-Liang; Lü, Xiao-Ying; Wang, Zhi-Gong

    2016-02-01

    Objective. Surface electromyography (sEMG) is often used as a control signal in neuromuscular electrical stimulation (NMES) systems to enhance the voluntary control and proprioceptive sensory feedback of paralyzed patients. Most sEMG-controlled NMES systems use the envelope of the sEMG signal to modulate the stimulation intensity (current amplitude or pulse width) with a constant frequency. The aims of this study were to develop a strategy that co-modulates frequency and pulse width based on features of the sEMG signal and to investigate the torque-reproduction performance and the level of fatigue resistance achieved with our strategy. Approach. We examined the relationships between wrist torque and two stimulation parameters (frequency and pulse width) and between wrist torque and two sEMG time-domain features (mean absolute value (MAV) and number of slope sign changes (NSS)) in eight healthy volunteers. By using wrist torque as an intermediate variable, customized and generalized transfer functions were constructed to convert the two features of the sEMG signal into the two stimulation parameters, thereby establishing a MAV/NSS dual-coding (MNDC) algorithm. Wrist torque reproduction performance was assessed by comparing the torque generated by the algorithms with that originally recorded during voluntary contractions. Muscle fatigue was assessed by measuring the decline percentage of the peak torque and by comparing the torque time integral of the response to test stimulation trains before and after fatigue sessions. Main Results. The MNDC approach could produce a wrist torque that closely matched the voluntary wrist torque. In addition, a smaller decay in the wrist torque was observed after the MNDC-coded fatigue stimulation was applied than after stimulation using pulse-width modulation alone. Significance. Compared with pulse-width modulation stimulation strategies that are based on sEMG detection, the MNDC strategy is more effective for both voluntary muscle

  13. Central implementation strategies outperform local ones in improving HIV testing in Veterans Healthcare Administration facilities.

    Science.gov (United States)

    Goetz, Matthew Bidwell; Hoang, Tuyen; Knapp, Herschel; Burgess, Jane; Fletcher, Michael D; Gifford, Allen L; Asch, Steven M

    2013-10-01

    Pilot data suggest that a multifaceted approach may increase HIV testing rates, but the scalability of this approach and the level of support needed for successful implementation remain unknown. To evaluate the effectiveness of a scaled-up multi-component intervention in increasing the rate of risk-based and routine HIV diagnostic testing in primary care clinics and the impact of differing levels of program support. Three arm, quasi-experimental implementation research study. Veterans Health Administration (VHA) facilities. Persons receiving primary care between June 2009 and September 2011 INTERVENTION: A multimodal program, including a real-time electronic clinical reminder to facilitate HIV testing, provider feedback reports and provider education, was implemented in Central and Local Arm Sites; sites in the Central Arm also received ongoing programmatic support. Control Arm sites had no intervention Frequency of performing HIV testing during the 6 months before and after implementation of a risk-based clinical reminder (phase I) or routine clinical reminder (phase II). The adjusted rate of risk-based testing increased by 0.4 %, 5.6 % and 10.1 % in the Control, Local and Central Arms, respectively (all comparisons, p marketing significantly increased the frequency at which HIV testing is offered and performed in VHA facilities. These findings support a multimodal approach toward achieving the goal of having every American know their HIV status as a matter of routine clinical practice.

  14. National Oceanic and Atmospheric Administration's Cetacean and Sound Mapping Effort: Continuing Forward with an Integrated Ocean Noise Strategy.

    Science.gov (United States)

    Harrison, Jolie; Ferguson, Megan; Gedamke, Jason; Hatch, Leila; Southall, Brandon; Van Parijs, Sofie

    2016-01-01

    To help manage chronic and cumulative impacts of human activities on marine mammals, the National Oceanic and Atmospheric Administration (NOAA) convened two working groups, the Underwater Sound Field Mapping Working Group (SoundMap) and the Cetacean Density and Distribution Mapping Working Group (CetMap), with overarching effort of both groups referred to as CetSound, which (1) mapped the predicted contribution of human sound sources to ocean noise and (2) provided region/time/species-specific cetacean density and distribution maps. Mapping products were presented at a symposium where future priorities were identified, including institutionalization/integration of the CetSound effort within NOAA-wide goals and programs, creation of forums and mechanisms for external input and funding, and expanded outreach/education. NOAA is subsequently developing an ocean noise strategy to articulate noise conservation goals and further identify science and management actions needed to support them.

  15. Evaluating the outcomes of complex nursing initiatives: Insights from the CANO/ACIO National Strategy for Chemotherapy Administration Project.

    Science.gov (United States)

    Thorne, Sally; Rashleigh, Laura; Truant, Tracy; Hartzell, Renée; McQuestion, Maurene

    2015-01-01

    Because nursing interventions are typically complex and dynamic, evaluating their impact upon care and care systems is a notoriously daunting challenge. Nursing organizations seeking to evaluate the impact of their efforts are frequently frustrated by the gap between the evaluation research ideal and their available resources. In this paper, we describe a practical and manageable process developed to address such an evaluation challenge. Using a three-step inquiry approach, supported by modest organizational funding and a realistic level of voluntary member time, we were able to generate a meaningful understanding of intersecting outcomes arising from the implementation of CANO/ACIO's National Strategy for Chemotherapy Administration. On the basis of our experience, we see considerable merit in both process and outcomes of this form of targeted evaluation.

  16. Determination of an optimal control strategy for drug administration in tumor treatment using multi-objective optimization differential evolution.

    Science.gov (United States)

    Lobato, Fran Sérgio; Machado, Vinicius Silvério; Steffen, Valder

    2016-07-01

    The mathematical modeling of physical and biologic systems represents an interesting alternative to study the behavior of these phenomena. In this context, the development of mathematical models to simulate the dynamic behavior of tumors is configured as an important theme in the current days. Among the advantages resulting from using these models is their application to optimization and inverse problem approaches. Traditionally, the formulated Optimal Control Problem (OCP) has the objective of minimizing the size of tumor cells by the end of the treatment. In this case an important aspect is not considered, namely, the optimal concentrations of drugs may affect the patients' health significantly. In this sense, the present work has the objective of obtaining an optimal protocol for drug administration to patients with cancer, through the minimization of both the cancerous cells concentration and the prescribed drug concentration. The resolution of this multi-objective problem is obtained through the Multi-objective Optimization Differential Evolution (MODE) algorithm. The Pareto's Curve obtained supplies a set of optimal protocols from which an optimal strategy for drug administration can be chosen, according to a given criterion.

  17. Research on Internal Relation Between Virtual Space Vector Pulse Width Modulation Strategy and Carrier Sinusoidal Pulse Width Modulation Strategy for Three-Level Neutral Point Clamped Converter%三电平NPC变流器虚拟空间矢量调制策略与载波调制策略的内在关系研究

    Institute of Scientific and Technical Information of China (English)

    李宁; 王跃; 蒋应伟; 雷万钧; 王兆安

    2014-01-01

    分析了虚拟空间矢量调制(virtual space vector pulse width modulation,VSVPWM)策略的基本原理,推导了三电平 VSVPWM 策略与单相双调制波三电平正弦脉冲宽度调制(sinusoidal pulse width modulation,SPWM)策略的内在联系,建立了两者间的调制波等效关系。应用调制波等效关系分析了 VSVPWM 策略的输出电压总谐波畸变率(total harmonic distortion,THD)、直流电压利用率和开关器件损耗。最后,提出了基于调制波等效关系的三电平VSVPWM快速实现方案。仿真和实验结果验证了理论分析的正确性。%In the modulation strategies for three-level NPC converter, neutral point voltage control under the entire modulation index and full power factor can be achieved by virtual space vector pulse width modulation (VSVPWM) strategy. In this paper the basic principle of VSVPWM is analyzed, then the internal relation between three-level VSVPWM strategy and single-phase dual modulation based three-level sinusoidal pulse width modulation (SPWM) strategy is derived and the modulation-wave equivalence between the two modulation strategies is established. Using the established modulation-wave equivalent relation, the total harmonic distortion (THD) of output voltage, DC voltage utilization rate and switch device losses under VSVPWM strategy are analyzed. Finally, a fast implementation of three-level VSVPWM strategy based on modulation-wave equivalence is proposed. The correctness of the theoretical analysis is verified by both results from simulation and experiments.

  18. Pulse on Pulse

    DEFF Research Database (Denmark)

    Schmidt, Ulrik; Carlson, Merete

    2012-01-01

    Pulse on Pulse” investigates the relation between signifying processes and non-signifying material dynamism in the installation Pulse Room (2006-) by Mexican Canadian artist Rafael Lozano-Hemmer. In Pulse Room the sense of pulse is ambiguous. Biorhythms are transmitted from the pulsing energy...... and pulsating ‘room’. Hence, the visitors in Pulse Room are invited into a complex scenario that continuously oscillates between various aspects of signification (the light bulbs representing individual lives; the pulse itself as the symbolic ‘rhythm of life’) and instants of pure material processuality...... a multilayered sense of time and space that is central to the sensory experience of Pulse Room as a whole. Pulse Room is, at the very same time, an anthropomorfized archive of a past intimacy and an all-encompassing immersive environment modulating continuously in real space-time....

  19. Strategies for diagnosing and alleviating artifactual attenuation associated with large gradient pulses in PGSE NMR diffusion measurements.

    Science.gov (United States)

    Price, W S; Hayamizu, K; Ide, H; Arata, Y

    1999-08-01

    The generation of phase-based artifacts resulting from mismatch in the effective areas (i.e., the time integrals) of sequential gradient pulses is discussed in the context of large gradient pulsed-gradient spin-echo (PGSE) NMR diffusion measurements. Such effects result in artifactual attenuation and distortion in the spectra which, in the first instance, are similar to (and commonly mistaken for) the effects of eddy currents. Small degrees of mismatch cause "unphysical" concave downward curvature in PGSE attenuation plots of freely diffusing species. However, larger mismatches can result in artifactual diffraction peaks in the plots which could easily be confused for true restricted diffusion effects. Although "rectangular" gradient pulses are preferable from a theoretical viewpoint, we found that shaped gradient (e.g., half-sine) pulses, which due to their slower rise and fall times were more tractable for the current amplifier, were more sequentially reproducible. As well as generating fewer phase-based artifacts such shaped pulses also decrease the likelihood of vibration problems.

  20. On Variant Strategies To Solve The Magnitude Least Squares Optimization Problem In Parallel Transmission Pulse Design And Under Strict SAR And Power Constraints

    CERN Document Server

    Hoyos-Iruarrizaga, Andres; Massire, Aurélien; Amadon, Alexis; Boulant, Nicolas

    2013-01-01

    Parallel transmission has been a very promising candidate technology to mitigate the inevitable radio-frequency field inhomogeneity in magnetic resonance imaging (MRI) at ultra-high field (UHF). For the first few years, pulse design utilizing this technique was expressed as a least squares problem with crude power regularizations aimed at controlling the specific absorption rate (SAR), hence the patient safety. This approach being suboptimal for many applications sensitive mostly to the magnitude of the spin excitation, and not its phase, the magnitude least squares (MLS) problem then was first formulated in 2007. Despite its importance and the availability of other powerful numerical optimization methods, this problem yet has been faced exclusively by the pulse designer with the so-called variable exchange method. In this paper, we investigate other strategies and incorporate directly the strict SAR and hardware constraints. Different schemes such as sequential quadratic programming (SQP), interior point (I-...

  1. How the Projects Implemented by the Ministry of Regional Development and Public Administration Have Impacted on the Strategies to Reform Public Administration

    Directory of Open Access Journals (Sweden)

    Madalina-Elena MIHAILESCU

    2016-09-01

    Full Text Available In Romania, the process to reform the administration is a mere mirage, similar to a Morgana, endlessly debated upon but little attained, especially through the perspective of the aims set by all the actors entrusted with revolutionizing the public system, be them related to politics or not. In its attempt to join and later to become an integral part of the European Union, Romania has experienced several social and political stages that were characterized by the attempt, through various procedures, to bring to a common denominator our administration with the European ones which are obviously more efficient and closer to the real needs of citizens as well as to the process to bringing public interest to high standards by means of quality public services. The paper herein introduces the aims of two projects that have recently been carried out by The Ministry of Regional Development and Public Administration in its attempt to collaborated with all the other authorities and public institutions in order to reform administration, namely POCA and The Development of tools and territorial planning models for the support of the subsequent period of programmes post 2013, both aimed to adjust a part of those deep problems that affect to efficient operation of the public institutions.

  2. Administrative Strategies of Departmental Heads as Determinants for the Effective Management of Human Resources in Tertiary Institutions in Delta State, Nigeria

    Science.gov (United States)

    Osakwe, Regina N.

    2015-01-01

    This study investigated administrative strategies of departmental heads as determinants of effective management of human resources in tertiary institutions. Four research questions were asked and four hypotheses were formulated to guide the study. As a descriptive survey, the population comprised all the eight tertiary institutions in the state…

  3. Pulse on Pulse

    DEFF Research Database (Denmark)

    Schmidt, Ulrik; Carlson, Merete

    2012-01-01

    and pulsating ‘room’. Hence, the visitors in Pulse Room are invited into a complex scenario that continuously oscillates between various aspects of signification (the light bulbs representing individual lives; the pulse itself as the symbolic ‘rhythm of life’) and instants of pure material processuality......“Pulse on Pulse” investigates the relation between signifying processes and non-signifying material dynamism in the installation Pulse Room (2006-) by Mexican Canadian artist Rafael Lozano-Hemmer. In Pulse Room the sense of pulse is ambiguous. Biorhythms are transmitted from the pulsing energy...... of the visitor’s beating heart to the blink of a fragile light bulb, thereby transforming each light bulb into a register of individual life. But at the same time the blinking light bulbs together produce a chaotically flickering light environment composed by various layers of repetitive rhythms, a vibrant...

  4. A spatial model with pulsed releases to compare strategies for the sterile insect technique applied to the mosquito Aedes aegypti.

    Science.gov (United States)

    Oléron Evans, Thomas P; Bishop, Steven R

    2014-08-01

    We present a simple mathematical model to replicate the key features of the sterile insect technique (SIT) for controlling pest species, with particular reference to the mosquito Aedes aegypti, the main vector of dengue fever. The model differs from the majority of those studied previously in that it is simultaneously spatially explicit and involves pulsed, rather than continuous, sterile insect releases. The spatially uniform equilibria of the model are identified and analysed. Simulations are performed to analyse the impact of varying the number of release sites, the interval between pulsed releases and the overall volume of sterile insect releases on the effectiveness of SIT programmes. Results show that, given a fixed volume of available sterile insects, increasing the number of release sites and the frequency of releases increases the effectiveness of SIT programmes. It is also observed that programmes may become completely ineffective if the interval between pulsed releases is greater that a certain threshold value and that, beyond a certain point, increasing the overall volume of sterile insects released does not improve the effectiveness of SIT. It is also noted that insect dispersal drives a rapid recolonisation of areas in which the species has been eradicated and we argue that understanding the density dependent mortality of released insects is necessary to develop efficient, cost-effective SIT programmes.

  5. Design and evaluation of polymer coated carvedilol loaded solid lipid nanoparticles to improve the oral bioavailability: a novel strategy to avoid intraduodenal administration.

    Science.gov (United States)

    Venishetty, Vinay Kumar; Chede, Raghavendra; Komuravelli, Rojarani; Adepu, Laxminarayana; Sistla, Ramakrishna; Diwan, Prakash V

    2012-06-15

    Solid lipid nanoparticles are most promising delivery systems for the enhancement of bioavailability of highly lipophilic drugs those prone to the first pass metabolism. But burst release of drug from solid lipid nanoparticles in acidic environment such as gastric milieu precludes its usage as oral delivery system. Studies on SLN revealed intraduodenal administration as an alternative route for SLN administration. But clinically it is an inappropriate route for repeated administration of drugs to patients. Hence, we prepared N-carboxymethyl chitosan (MCC) coated carvedilol loaded SLN to protect the rapid release of carvedilol in acidic environment. Positively charged carvedilol loaded SLN were developed using monoglyceride as lipid and soya lecithin and poloxamer 188 as surfactants and stearylamine as charge modifier. These SLN were characterized for particle size, zeta potential, entrapment efficiency, crystallinity and stability studies. Further these SLN were coated with N-carboxymethyl chitosan and confirmed by change in zetapotential and X-ray Photon Spectroscopic analysis. Effect of polymer coating on drug release profiles were studied simulated gastric and intestinal fluids. Effect of polymer coating on oral bioavailability of carvedilol loaded SLN were studied in rats after oral administration. MCC coated SLN improved the bioavailability of carvedilol compared uncoated SLN after oral administration. Insignificant difference in bioavailability was observed compared to intraduodenal administration of SLN. Hence, MCC coated SLN is a novel strategy to avoid intrduodenal administration.

  6. Administrator Strategies that Support High Fidelity Implementation of the Pyramid Model for Promoting Social-Emotional Competence & Addressing Challenging Behavior

    Science.gov (United States)

    Mincic, Melissa; Smith, Barbara J.; Strain, Phil

    2009-01-01

    Implementing the Pyramid Model with fidelity and achieving positive outcomes for children and their families requires that administrators understand their roles in the implementation process. Every administrative decision impacts program quality and sustainability. This Policy Brief underscores the importance of facilitative administrative…

  7. COMBINATIONAL ADMINISTRATION OF AMINOGLYCOSIDES AND LOOP DIURETICS AS AN EFFICIENT STRATEGY TO ESTABLISH DEAFNESS MODELS IN RATS

    Institute of Scientific and Technical Information of China (English)

    CONG Tao; LIU Riyuan; YUAN Shuolong; XU Liangwei; YANG Shiming

    2014-01-01

    It is known that aminoglycoside antibiotics can damage the vestibular and auditory sensory epithelia, and the loop diuretics can enhance the ototoxic effect of aminoglycosides. Previous studies on the synergistic effect of these two types of drugs have used mice, guinea pigs and cats, but not rats. The aim of this study was to determine this synergistic effects in rat cochleae. Rats received intravenous injections of different doses of furosemide and/or intramuscular injections of kanamycin sulfate. Au-ditory brainstem response (ABR), scanning electron microscopy (SEM) and immunocytochemistry were used to determine the effects of drug administration. In the group receiving combined administration of furosemide and kanamycin, the ABR thresh-old showed significant elevation 3 days after drug administration, greater than single drug administration. The hair cells showed various degrees of injury from the apical turn to the basal turn of the cochlea and from the outer hair cells to the inner hair cells. Neuron fibers of the hair cells showed significant loss 7 days after the drug administration, but the number of spiral ganglia did not decrease and supporting cells showed no signs of injury. Our study suggest that combined administration of fu-rosemide and kanamycin has an synergistic ototoxic effect, and can result in hair cell loss and hearing loss in rats.

  8. Choosing the best pulse sequences, acquisition parameters, postacquisition processing strategies, and probes for natural product structure elucidation by NMR spectroscopy.

    Science.gov (United States)

    Reynolds, William F; Enríquez, Raúl G

    2002-02-01

    The relative merits of different pairs of two-dimensional NMR pulse sequences (COSY-90 vs COSY-45, NOESY vs T-ROESY, HSQC vs HMQC, HMBC vs CIGAR, etc.) are compared and recommendations are made for the preferred choice of sequences for natural product structure elucidation. Similar comparisons are made between different selective 1D sequences and the corresponding 2D sequences. Many users of 2D NMR use longer than necessary relaxation delays and neglect to use forward linear prediction processing. It is shown that using shorter relaxation delays in combination with forward linear prediction allows one to get better resolved spectra in less time. The relative merits of different probes and likely future probe developments are also discussed.

  9. 乡镇行政人员在行政过程中的失范与应对策略%Township Administrative Staff's Anomie in Process of Administration and Coping Strategies

    Institute of Scientific and Technical Information of China (English)

    唐跟利

    2015-01-01

    当前,我国正处于经济和社会加快发展和即将转型的关键时期。基层也面临发展与转型等考验,各种矛盾利益交织,一旦处理不当,很有可能使矛盾更加激化,基层政府治理难度空前加剧。管理中人是第一要素,而乡镇行政人员在行政过程中出现乱作为、不作为等失范现象。为此,思考我国乡镇行政人员行政过程中行为失范产生的原因并提出应对策略迫在眉睫。%At present, our country is in the key period of accelerate development and transformation of economy and society. The grass-roots is also facing the test of development and transformation, all kinds of in-terests and contradictions are mixed. If the contradictions will be improper handled, it is likely to make more intensify contradictions, and grass-roots governance difficulty will be unprecedented. People is the first element in the management, but the township administrative staff have the anomie phe-nomenon such as disorderly action, omission or illegal administration in the process of administration. So it is imminent to think deeply the reason of township administrative staffˊs anomie in the process of administration and put forward coping strategies.

  10. The Veterans Health Administration: quality, value, accountability, and information as transforming strategies for patient-centered care.

    Science.gov (United States)

    Perlin, Johnathan B; Kolodner, Robert M; Roswell, Robert H

    2005-01-01

    The Veterans Health Administration is the United States' largest integrated health system. Once disparaged as a bureaucracy providing mediocre care, the Department of Veterans Affairs (VA) reinvented itself during the past decade through a policy shift mandating structural and organizational change, rationalization of resource allocation, explicit measurement and accountability for quality and value, and development of an information infrastructure supporting the needs of patients, clinicians, and administrators. Today, the VA is recognized for leadership in clinical informatics and performance improvement, cares for more patients with proportionally fewer resources, and sets national benchmarks in patient satisfaction and for 18 indicators of quality in disease prevention and treatment.

  11. Successful Reading Strategies To Meet the Texas Reading Initiative Components: A Literary Review and Manual for Administrators, Teachers, and Parents.

    Science.gov (United States)

    Baker, Bridget; Karr-Kidwell, PJ

    This paper provides a literary review and research-based techniques for teaching reading. The paper also examines the different philosophies of reading to ascertain beneficial commonalities. Based on the literature review, a manual was produced to support administrators, teachers, and parents in securing quality reading instruction. Appendix A…

  12. Pulse-Reverse Electrodeposition and Micromachining of Graphene-Nickel Composite: An Efficient Strategy toward High-Performance Microsystem Application.

    Science.gov (United States)

    Li, Jinhua; An, Zhonglie; Wang, Zhuqing; Toda, Masaya; Ono, Takahito

    2016-02-17

    Graphene reinforced nickel (Ni) is an intriguing nanocomposite with tremendous potential for microelectromechanical system (MEMS) applications by remedying mechanical drawbacks of the metal matrix for device optimization, though very few related works have been reported. In this paper, we developed a pulse-reverse electrodeposition method for synthesizing graphene-Ni (G-Ni) composite microcomponents with high content and homogeneously dispersed graphene filler. While the Vickers hardness is largely enhanced by 2.7-fold after adding graphene, the Young's modulus of composite under dynamic condition shows ∼1.4-fold increase based on the raised resonant frequency of a composite microcantilever array. For the first time, we also demonstrate the application of G-Ni composite in microsystems by fabricating a Si micromirror with the composite supporting beams as well as investigate the long-term stability of the mirror at resonant vibration. Compared with the pure Ni counterpart, the composite mirror shows an apparently lessened fluctuations of resonant frequency and scanning angle due to a suppressed plastic deformation even under the sustaining periodic loading. This can be ascribed to the reduced grain size of Ni matrix and dislocation hindering in the presence of graphene by taking into account the crystalline refinement strengthen mechanism. The rational discussions also imply that the strong interface and efficient load transfer between graphene layers and metal matrix play an important role for improving stiffness in composite. It is believed that a proper design of graphene-metal composite makes it a promising structural material candidate for advanced micromechanical devices.

  13. High Feed Stability Control Strategies for Pulse Driving Systems%脉冲进给系统的高平稳运动控制

    Institute of Scientific and Technical Information of China (English)

    何均; 游有鹏; 王化明; 朱剑英

    2011-01-01

    The feed motion stability of pulse driving systems is directly affected by characters of driving pulse sequences generated by CNC interpolators. The motion stability and control strategies are investigated by theoretical analysis, modeling simulation and experimental verification. Based on the mathematical model of interpolator output, the motion stability is discussed in both time-domain and frequency-domain. For traditional interpolation mode, an approach of improving motion stability is given according to the inter-restricted relation among machining accuracy, efficiency and motion stability. Furthermore, breaking through the traditional control mode, a new interpolating control strategy -an adaptive separated-axis interpolator with random period-is proposed to achieve high motion quality by varying interpolation period and synchronization of multi-axes. The results of simulations and machining experiments show the proposed strategies are effective. The efforts described provide new ways to improve the motion stability theoretically and practically.%数控系统插补产生的驱动脉冲序列特性直接影响到脉冲进给系统的运动平稳性.通过理论分析、建模仿真和试验验证系统研究脉冲进给系统的运动平稳性问题及其控制对策.在建立插补输出模型的基础上,从时域和频域剖析了其平稳性问题的本质;根据所揭示的精度、效率和平稳性之间的制约关系给出传统模式下实现平稳运动控制的途径;并从改变插补周期及多轴联动方式入手,突破传统数控的插补控制模式,提出全新的高平稳运动控制方案--随机周期独立轴自适应插补控制.大量的时域和频域仿真及实际加工试验验证所提算法的有效性.为改善数控设备的运动平稳性提供了理论依据和全新途径.

  14. Pulse pattern modulated strategy for harmonic current components reduction in three-phase AC-DC converters

    DEFF Research Database (Denmark)

    Davari, Pooya; Zare, Firuz; Blaabjerg, Frede

    2015-01-01

    Generated harmonic current as a consequence of employing power electronics converter is known as an important power quality issue in distribution networks. From industry point of view complying with international standards is mandatory, however cost and efficiency are two other important features......, which need to be considered in order to be competitive in the market. Therefore, having a flexibility to meet various requirements imposed by the standard recommendations or costumer needs is at most desirable. This makes the generated harmonic current mitigation a challenging task especially with three......-phase diode bridge rectifier, which still is preferred in many power electronic systems. This paper addresses a novel current modulation strategy using a single-switch boost three-phase diode bridge rectifier. The proposed method can selectively mitigate current harmonics, which makes it suitable...

  15. Pulse Pattern-Modulated Strategy for Harmonic Current Components Reduction in Three-Phase AC–DC Converters

    DEFF Research Database (Denmark)

    Davari, Pooya; Zare, Firuz; Blaabjerg, Frede

    2016-01-01

    Generated harmonic current as a consequence of employing power electronics converter is known as an important power quality issue in distribution networks. From industry point of view complying with international standards is mandatory, however cost and efficiency are two other important features......, which need to be considered in order to be competitive in the market. Therefore, having a flexibility to meet various requirements imposed by the standard recommendations or costumer needs is at most desirable. This makes the generated harmonic current mitigation a challenging task especially with three......-phase diode bridge rectifier, which still is preferred in many power electronic systems. This paper addresses a novel current modulation strategy using a single-switch boost three-phase diode bridge rectifier. The proposed method can selectively mitigate current harmonics, which makes it suitable...

  16. THE ROLE OF STRATEGIES FOR PREVENTION AND ADMINISTRATION OF ORGANIZATIONAL STRESS ON THE EFFICIENCY OF HUMAN RESOURCES

    Directory of Open Access Journals (Sweden)

    Mituţ Iulian

    2011-12-01

    Full Text Available In knowledge-based organizations the stress becomes predictable and success ends up dependent on antistress organizational strategies, on the non-financial motivation and efficiency of human resource. Such human resources strategies influence organization’s excellence in crisis or normal situations. The pressures and tensions of organizational environment have amplified and changed the way/ lifestyle of the individual and organizations, they changed political, economic and organizational decisions. The study of organizational stress in an occupational environment with extremely high expectations enables the formulation of conclusions regarding the influence of organizational strategies on human resources and organizational efficiency. Stress management in modern organizational environment is a prerequisite for organizational performance, competitiveness and organizational success, requiring strategic approach and theoretical / practical knowledge. The aim of this study is to analyze the relationship between organizational stress and the satisfaction of human resource in organization. The main objectives of research aim at: 1 elaboration of organizational stress diagnosis in the military environment and 2 analysis of the effects of organizational stress in the same organizational environment. The study analyzes the index of organizational stress and stress effects according to the satisfaction with organization and job on a sample of 66 subjects. The analysis of correlations between variables revealed the influence of organizational stress upon the satisfaction with organization and job, i.e. individual's motivational system that plays the essential role in achieving organizational excellence.

  17. A Review of Modern Control Strategies for Clinical Evaluation of Propofol Anesthesia Administration Employing Hypnosis Level Regulation

    Science.gov (United States)

    Ilyas, Muhammad; Bilal, Muhammad; Mahmood, Khalid; Ali Riaz, Raja

    2017-01-01

    Regulating the depth of hypnosis during surgery is one of the major objectives of an anesthesia infusion system. Continuous administration of Propofol infusion during surgical procedures is essential but it unduly increases the load of an anesthetist working in a multitasking scenario in the operation theatre. Manual and target controlled infusion systems are not appropriate to handle instabilities like blood pressure and heart rate changes arising due to interpatient and intrapatient variability. Patient safety, large interindividual variability, and less postoperative effects are the main factors motivating automation in anesthesia administration. The idea of automated system for Propofol infusion excites control engineers to come up with more sophisticated systems that can handle optimum delivery of anesthetic drugs during surgery and avoid postoperative effects. A linear control technique is applied initially using three compartmental pharmacokinetic and pharmacodynamic models. Later on, sliding mode control and model predicative control achieve considerable results with nonlinear sigmoid model. Chattering and uncertainties are further improved by employing adaptive fuzzy control and H∞ control. The proposed sliding mode control scheme can easily handle the nonlinearities and achieve an optimum hypnosis level as compared to linear control schemes, hence preventing mishaps such as underdosing and overdosing of anesthesia. PMID:28466018

  18. A Review of Modern Control Strategies for Clinical Evaluation of Propofol Anesthesia Administration Employing Hypnosis Level Regulation

    Directory of Open Access Journals (Sweden)

    Muhammad Ilyas

    2017-01-01

    Full Text Available Regulating the depth of hypnosis during surgery is one of the major objectives of an anesthesia infusion system. Continuous administration of Propofol infusion during surgical procedures is essential but it unduly increases the load of an anesthetist working in a multitasking scenario in the operation theatre. Manual and target controlled infusion systems are not appropriate to handle instabilities like blood pressure and heart rate changes arising due to interpatient and intrapatient variability. Patient safety, large interindividual variability, and less postoperative effects are the main factors motivating automation in anesthesia administration. The idea of automated system for Propofol infusion excites control engineers to come up with more sophisticated systems that can handle optimum delivery of anesthetic drugs during surgery and avoid postoperative effects. A linear control technique is applied initially using three compartmental pharmacokinetic and pharmacodynamic models. Later on, sliding mode control and model predicative control achieve considerable results with nonlinear sigmoid model. Chattering and uncertainties are further improved by employing adaptive fuzzy control and H∞ control. The proposed sliding mode control scheme can easily handle the nonlinearities and achieve an optimum hypnosis level as compared to linear control schemes, hence preventing mishaps such as underdosing and overdosing of anesthesia.

  19. Enterprise iPhone and iPad Administrator's Guide Strategies for iPhone Deployment, Integration, and Control

    CERN Document Server

    Edge, Charles

    2010-01-01

    Are you an IT professional involved in deploying the iPhone and or iPad in your company or organization? Do you have fellow employees who are eager to use their iPhones and iPads for work? Then this is the book for you. Enterprise iPhone and iPad Administrator's Guide provides step-by-step instructions on how to deploy and integrate the iPhone within a range of professional environments - from large businesses and educational institutions to medium-sized offices. This book ensures that the process is achieved in a streamlined, efficient, and cost-effective manner. The guide begins with an intr

  20. Pulsed Single Frequency MOPA Laser Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Latest advances in semiconductor optoelectronics makes it possible to develop compact light weight robust sources of coherent optical pulses, demanded for numerous...

  1. Analysis of International Organizations Strategy of Obama Administration%奥巴马政府国际组织策略研究

    Institute of Scientific and Technical Information of China (English)

    董川

    2016-01-01

    自奥巴马政府2009年上台以来,美国从自身实力及全球战略出发,对外交政策做了调整。奥巴马政府对武力的使用十分谨慎,主张采用外交途径,先通过谈判和对话的方式解决问题。奥巴马政府重视与联合国、国际货币基金组织、北约以及东盟等国际组织的关系。其国际组织策略体现在试图发挥美国的重要作用,既利用国际组织又拒绝多边主义的束缚以及重视盟友的作用。针对奥巴马政府的国际组织策略和相关启示,中国应科学制定国际组织战略,积极参与国际制度和规则的创建,增加对国际组织的支持力度进而获取更多话语权。%Since the Obama administration took office in 2009 , the United States adjusted its foreign policy on the basis of its national power and international strategy. The Obama administration is very cautious of using force. It advocates the use of diplomatic channels to resolve conflicts. It attaches importance to relations with the United Nations,IMF,NATO,ASEAN and some other international organizations. The Obama administration’ s in-ternational organizations strategy is to ensure the American leadership,pay attention to international organizations but refuse the bound of multilateralism,as well as emphasize the role of allies. Thus,China should scientifically formulate its own international organizations strategy,respect the existing international order and strengthen coop-eration with the United States in various international organizations. Besides,it needs to increase its support to in-ternational organizations so as to get more power of discourse.

  2. Pulse Voltammetry.

    Science.gov (United States)

    Osteryoung, Janet

    1983-01-01

    Discusses the nature of pulse voltammetry, indicating that its widespread use arises from good sensitivity and detection limits and from ease of application and low cost. Provides analytical and mechanistic applications of the procedure. (JN)

  3. Pulsed Electrogasdynamic Thruster for Attitude Control and Orbit Maneuver Project

    Data.gov (United States)

    National Aeronautics and Space Administration — A new pulsed electric thruster, named "pulsed electrogasdynamic thruster," for attitude control and orbit maneuver is proposed. In this thruster, propellant gas is...

  4. A novel strategy combining magnetic particle hyperthermia pulses with enhanced performance binary ferrite carriers for effective in vitro manipulation of primary human osteogenic sarcoma cells.

    Science.gov (United States)

    Makridis, Antonios; Tziomaki, Magdalini; Topouridou, Konstantina; Yavropoulou, Maria P; Yovos, John G; Kalogirou, Orestis; Samaras, Theodoros; Angelakeris, Mavroeidis

    2016-11-01

    The present study examines the heating efficiency of a combination of manganese or cobalt ferrites in a binary (Co- or Mn-) ferrite nanoparticle form with magnetite, covered with citric acid to improve biocompatibility. The nanoparticle synthesis is based on the aqueous co-precipitation of proper salts, a facile, low-cost, environmentally friendly and high yield synthetic approach. By detailed structural and magnetic characterisation, the direct influence of structural and magnetic features on magnetic hyperthermia concludes to optimum heating efficiency. At a second stage, best performing magnetic nanoparticles undergo in vitro testing in three cell lines: one cancer cell line and two reference healthy cell lines. Both binary ferrite (MnFe2O4/Fe3O4 and CoFe2O4/Fe3O4) appear to be internalised and well tolerated by the cells while a versatile hyperthermia protocol is attempted in an effort to further improve their in vitro performance. Within this protocol, hyperthermia sequences are split in two runs with an intermediate 48 h time interval cell incubation stage while in each run a variable field mode (single or multiple pulses) is applied. Single-pulse field mode represents a typical hyperthermia application scheme where cells undergo the thermal shock continuously. On the other hand multiple-pulses mode refers to multiple, much shorter in duration AC field changes (field ON/OFFs), at each hyperthermia run, resulting eventually in high heating rate and much more harmful cell treatment. Consequently, we propose a novel series of improved performance heat mediators based on ferrite structures which show maximum efficiency at cancer cells when combined with a versatile multiple-pulse hyperthermia module.

  5. Pulse plating

    CERN Document Server

    Hansal, Wolfgang E G; Green, Todd; Leisner, Peter; Reichenbach, Andreas

    2012-01-01

    The electrodeposition of metals using pulsed current has achieved practical importance in recent years. Although it has long been known that changes in potential, with or without polarity reversal, can significantly affect the deposition process, the practical application of this has been slow to be adopted. This can largely be explained in terms of the complex relationship between the current regime and its effect on the electrodeposition process. In order to harness these effects, an understanding of the anodic and cathodic electrochemical processes is necessary, together with the effects of polarity reversal and the rate of such reversals. In this new monograph, the basics of metal electrodeposition from solution are laid out in great detail in seven distinct chapters. With this knowledge, the reader is able to predict how a given pulse train profile can be adopted to achieve a desired outcome. Equally important is the choice of a suitable rectifier and the ancillary control circuits to enable pulse platin...

  6. Problems and Coping Strategies of G2C Administrative Ethics Performance Evaluation%G2 C行政伦理绩效评估的问题及其应对策略

    Institute of Scientific and Technical Information of China (English)

    邢勤锋

    2014-01-01

    In this paper,based on the analysis of G2C administrative ethics,public administration values and China’s administrative reform,the author studies G2C the administrative ethics and the performance evaluation,summarizes the problems and shortcomings of the G2C administra-tive ethics performance evaluation,and proposes some strategies to improve the administrative G2C ethical performance evaluation.%在分析G2 C行政伦理对公共行政价值以及中国行政体制改革的重要意义的基础上,梳理G2 C行政伦理及其绩效评估的现状,归纳总结了现行 G2 C 行政伦理绩效评估存在的问题与不足,提出了完善G2 C行政伦理绩效评估的策略。

  7. Strategy for copper speciation in white wine by differential pulse anodic stripping voltammetry, potentiometry with an ion-selective electrode and kinetic photometric determination

    Energy Technology Data Exchange (ETDEWEB)

    Wiese, C. [Inst. fuer Anorganische und Analytische Chemie, Technische Univ. Clausthal, Clausthal-Zellerfeld (Germany); Schwedt, G. [Inst. fuer Anorganische und Analytische Chemie, Technische Univ. Clausthal, Clausthal-Zellerfeld (Germany)

    1997-07-01

    Differential pulse anodic stripping voltammetry (DPASV), potentiometry with a copper ion-selective electrode and a kinetic photometric method were used to determine copper species in white wines. The kinetic method is based on the catalytic effect of labile copper(II) species on the oxidation of 3-hydroxybenzaldehyde azine by potassium peroxidisulfate in an ammonical medium at room temperature. The total copper concentrations were determined by flame atomic absorption spectrometry. Free copper(II) ions, labile and tightly bound copper species could be quantified in 16 non pre-treated wine samples. (orig.). With 3 figs., 5 tabs.

  8. Strategy for Coordinated EPA/Occupational Safety and Health Administration (OSHA) Implementation of the Chemical Accident Prevention Requirements of the Clean Air Act Amendments of 1990

    Science.gov (United States)

    EPA and the Occupational Safety and Health Administration (OSHA) share responsibility for prevention: OSHA has the Process Safety Management Standard to protect workers, and EPA the Risk Management Program to protect the general public and environment.

  9. Administrating Solr

    CERN Document Server

    Mohan, Surendra

    2013-01-01

    A fast-paced, example-based guide to learning how to administrate, monitor, and optimize Apache Solr.""Administrating Solr"" is for developers and Solr administrators who have a basic knowledge of Solr and who are looking for ways to keep their Solr server healthy and well maintained. A basic working knowledge of Apache Lucene is recommended, but this is not mandatory.

  10. 一类具有脉冲预防接种的SEIRS传染病模型的研究%A Study of SEIRS Epidemic Model with Pulse Vaccination Strategy

    Institute of Scientific and Technical Information of China (English)

    芦雪娟; 董晓红; 张敬

    2011-01-01

    In this paper, a disease transmission model of SEIRS type with pulse vaccination strategy is studied. We obtain the existence conditions with the global attractive of infection-free periodic solution by the analysis of the equivalent system of the model, and give the existence of the persistent of the disease.%研究了一类具有脉冲预防接种的SEIRS传染病模型,利用对模型等价系统的分析,得到了模型无病周期解具有全局吸引性的存在条件,并且给出了疾病的持久性的存在条件.

  11. Pulsed thermoelectricity

    Science.gov (United States)

    Apostol, M.; Nedelcu, M.

    2010-07-01

    A special mechanism of thermoelectric transport is described, consisting of pulses of charge carriers which "fly" periodically through the external circuit from the hot end of the sample to the cold end, with a determined duration of the "on" and "off" times of the electric contacts, while maintaining continuously the thermal contacts. It is shown that such a "resonant" ideal thermogenerator may work cyclically, with the same efficiency quotient as the ideal efficiency quotient of the thermoelectric devices operated in the usual stationary transport regime but the electric flow and power are increased, as a consequence of the concentration of the charge carriers on pulses of small spatial extent. The process is reversible, in the sense that it can be operated either as a thermoelectric generator or as an electrothermal cooler.

  12. Administrative Circulars

    CERN Multimedia

    Département des Ressources humaines

    2004-01-01

    Administrative Circular N° 2 (Rev. 2) - May 2004 Guidelines and procedures concerning recruitment and probation period of staff members This circular has been revised. It cancels and replaces Administrative Circular N° 2 (Rev. 1) - March 2000. Administrative Circular N° 9 (Rev. 3) - May 2004 Staff members contracts This circular has been revised. It cancels and replaces Administrative Circular N° 9 (Rev. 2) - March 2000. Administrative Circular N° 26 (Rev. 4) - May 2004 Procedure governing the career evolution of staff members This circular has also been revised. It Administrative Circulars Administrative Circular N° 26 (Rev. 3) - December 2001 and brings up to date the French version (Rev. 4) published on the HR Department Web site in January 2004. Operational Circular N° 7 - May 2004 Work from home This circular has been drawn up. Operational Circular N° 8 - May 2004 Dealing with alcohol-related problems...

  13. Advancing Performance Pay in the Obama Administration: The Influence of Political Strategy and Alternative Priorities. Program on Education Policy and Governance Working Papers Series. PEPG 10-04

    Science.gov (United States)

    Smarick, Andrew

    2010-01-01

    Even the most cursory look at the current administration's approach to performance pay reveals a noteworthy story. Unlike all of his Democratic predecessors--and some of his Republican ones--President Obama not only appreciates the value of differentiating the compensation of teachers based on a effectiveness, he has put energy and money behind…

  14. A pulse-chase strategy combining click-EdU and photoconvertible fluorescent reporter: tracking Golgi protein dynamics during the cell cycle.

    Science.gov (United States)

    Bourge, Mickaël; Fort, Cécile; Soler, Marie-Noëlle; Satiat-Jeunemaître, Béatrice; Brown, Spencer C

    2015-01-01

    Imaging or quantifying protein synthesis in cellulo through a well-resolved analysis of the cell cycle (also defining G1 subcompartments) is a methodological challenge. Click chemistry is the method of choice to reveal the thymidine analogue 5-ethynyl-2'-deoxyuridine (EdU) and track proliferating nuclei undergoing DNA synthesis. However, the click reaction quenches fluorescent proteins. Our challenge was to reconcile these two tools. A robust protocol based on a high-resolution cytometric cell cycle analysis in tobacco (Nicotiana tabacum) BY2 cells expressing fluorescent Golgi markers has been established. This was broadly applicable to tissues, cell clusters, and other eukaryotic material, and compatible with Scale clearing. EdU was then used with the photoconvertible protein sialyl transferase (ST)-Kaede as a Golgi marker in a photoconversion pulse-chase cytometric configuration resolving, in addition, subcompartments of G1. Quantitative restoration of protein fluorescence was achieved by introducing acidic EDTA washes to strip the copper from these proteins which were then imaged at neutral pH. The rate of synthesis of this Golgi membrane marker was low during early G1, but in the second half of G1 (30% of cycle duration) much of the synthesis occurred. Marker synthesis then persisted during S and G2. These insights into Golgi biology are discussed in terms of the cell's ability to adapt exocytosis to cell growth needs.

  15. Administrative Reform

    DEFF Research Database (Denmark)

    Plum, Maja

    Through the example of a Danish reform of educational plans in early childhood education, the paper critically addresses administrative educational reforms promoting accountability, visibility and documentation. Drawing on Foucaultian perspectives, the relation between knowledge and governing...... of administrative technology, tracing how the humanistic values of education embed and are embedded within ‘the professional nursery teacher' as an object and subject of administrative practice. Rather than undermining the humanistic potential of education, it is argued that the technology of accounting...

  16. 78 FR 14097 - Pulse Oximeters-Premarket Notification Submissions [510(k)s]; Guidance for Industry and Food and...

    Science.gov (United States)

    2013-03-04

    ... HUMAN SERVICES Food and Drug Administration Pulse Oximeters--Premarket Notification Submissions... availability of the guidance entitled ``Pulse Oximeters--Premarket Notification Submissions .'' This guidance document pertains to non-invasive pulse oximeters intended for prescription use to measure arterial...

  17. A novel pulse-chase SILAC strategy measures changes in protein decay and synthesis rates induced by perturbation of proteostasis with an Hsp90 inhibitor.

    Directory of Open Access Journals (Sweden)

    Ivo Fierro-Monti

    Full Text Available Standard proteomics methods allow the relative quantitation of levels of thousands of proteins in two or more samples. While such methods are invaluable for defining the variations in protein concentrations which follow the perturbation of a biological system, they do not offer information on the mechanisms underlying such changes. Expanding on previous work [1], we developed a pulse-chase (pc variant of SILAC (stable isotope labeling by amino acids in cell culture. pcSILAC can quantitate in one experiment and for two conditions the relative levels of proteins newly synthesized in a given time as well as the relative levels of remaining preexisting proteins. We validated the method studying the drug-mediated inhibition of the Hsp90 molecular chaperone, which is known to lead to increased synthesis of stress response proteins as well as the increased decay of Hsp90 "clients". We showed that pcSILAC can give information on changes in global cellular proteostasis induced by treatment with the inhibitor, which are normally not captured by standard relative quantitation techniques. Furthermore, we have developed a mathematical model and computational framework that uses pcSILAC data to determine degradation constants kd and synthesis rates Vs for proteins in both control and drug-treated cells. The results show that Hsp90 inhibition induced a generalized slowdown of protein synthesis and an increase in protein decay. Treatment with the inhibitor also resulted in widespread protein-specific changes in relative synthesis rates, together with variations in protein decay rates. The latter were more restricted to individual proteins or protein families than the variations in synthesis. Our results establish pcSILAC as a viable workflow for the mechanistic dissection of changes in the proteome which follow perturbations. Data are available via ProteomeXchange with identifier PXD000538.

  18. PULSE COLUMN

    Science.gov (United States)

    Grimmett, E.S.

    1964-01-01

    This patent covers a continuous countercurrent liquidsolids contactor column having a number of contactor states each comprising a perforated plate, a layer of balls, and a downcomer tube; a liquid-pulsing piston; and a solids discharger formed of a conical section at the bottom of the column, and a tubular extension on the lowest downcomer terminating in the conical section. Between the conical section and the downcomer extension is formed a small annular opening, through which solids fall coming through the perforated plate of the lowest contactor stage. This annular opening is small enough that the pressure drop thereacross is greater than the pressure drop upward through the lowest contactor stage. (AEC)

  19. A Space Vector Pulse Width Modulation Based Optimization Control Strategy for Hybrid Cascaded 7-Level Inverter%基于SVPWM调制的混合级联七电平逆变器优化控制策略

    Institute of Scientific and Technical Information of China (English)

    耿俊利; 梁晖; 金渊

    2015-01-01

    The working modes of hybrid cascaded 7-level inverter with dead zone are analyzed and analysis results show that there are different jumping situations of inverter voltage under different working modes. On this basis, based on space vector pulse width modulation (SVPWM) strategy an optimal control method is proposed. In the premise that the supporting capacitor voltage is under the control, through analyzing the jumping of output voltage level and the valve action times corresponding to the charging/discharging process of supporting capacity voltage switching in each interval an optimal control strategy to reduce the jumping of output voltage is put forward; besides, the output voltage loss due to the existence of dead zone time is analyzed and calculated according to the principle of volt-second balance, and the dead zone compensation for its modulation wave is performed. The effectiveness of the proposed control strategy is validated by results of simulation and experiments.%分析混合级联七电平逆变器带死区时的工作模式,不同工作模式下其逆变器电压的跳变情况不同。在此基础上,提出了基于空间矢量脉冲调制(space vector pulse width modulation,SVPWM)策略的优化控制方法。以控制支撑电容电压为前提,通过对每个区间支撑电容充放电切换过程所对应的开关动作次数、输出电压电平跳变情况的分析,提出了一种减小输出电压跳变的优化控制策略;此外,分析了死区时间的存在所带来的输出电压损失,根据伏秒平衡原理进行计算,并对其调制波进行死区补偿。仿真及实验结果验证了该控制策略的有效性。

  20. Administrative Ecology

    Science.gov (United States)

    McGarity, Augustus C., III; Maulding, Wanda

    2007-01-01

    This article discusses how all four facets of administrative ecology help dispel the claims about the "impossibility" of the superintendency. These are personal ecology, professional ecology, organizational ecology, and community ecology. Using today's superintendency as an administrative platform, current literature describes a preponderance of…

  1. Fiber Coupled Pulse Shaper for Sub-Nanosecond Pulse Lidar Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This Small Business Innovation Research Phase II effort will develop an all-diode laser and fiber optic based, single frequency, sub-nanosecond pulsed laser source...

  2. Discuss the administration pattern of special purpose cosmetics difference and strategy between China and foreign counties from medication regulatory administration angle of view%从药品监管职能视角探讨国内外特殊用途化妆品监管模式差异性及对策

    Institute of Scientific and Technical Information of China (English)

    徐昊; 王子寿; 何韦静; 谢婷

    2015-01-01

    Objective Discuss the administration pattern of special purpose cosmetics between China and foreign countries from medication regulatory administration angle of view, and provide advice and strategies to complete the special purpose cosmetics administration in China. Methods According to literature and investigation, analysis andgeneralize the difference of special purpose cosmetics regulatory administration pattern between China and America, Japan, EU. Results There are unities in making law and regulation about cosmetics administration and regulation department defining responsibility both in China and foreign countries. There are differences in definition, classification, material controlling, publicity, label management and post marketing administration. Conclusions Draw on the experience of abroad cosmetics administration pattern and management experience, make further efforts to complete the Special purpose cosmetics regulation, strengthen managing material, publicity, label and post marketing administration scientifically with the actual situation of cosmetics development in China to promote Chinese cosmetics industry’s sustainable development.%目的:从药品监管职能视角探讨国内外特殊用途化妆品监管模式,提出我国完善特殊化妆品监管的建议和对策。方法:通过文献与调研,分析、归纳中国、美国、日本和欧盟的特殊化妆品监管模式的差异性。结果:国内外在化妆品监管的法律、法规制定和监管部门确定与职责方面具有同一性,定义及分类、原料管理、宣传、标识管理和上市后监管等方面存在差异性。结论:借鉴国外化妆品监管模式及管理经验,结合我国化妆品发展的国情与实际,进一步完善特殊用途化妆品的规章制度,强化原料,宣传、标识和上市后监管等方面的科学管理,以促进我国化妆品行业的可持续发展。

  3. Offentlig administration

    DEFF Research Database (Denmark)

    Nielsen, Elof Nellemann; Rehr, Preben René

    En undervisningsbog der henvender sig til administrationsbacheloruddannelsen. Kapitlerne er inddelt efter modulerne på uddannelsen og indeholder derfor elementer af administration, forvaltning, økonomistyring, innovation, samfundsvidenskabelige metoder og politisk styrede organisationer.......En undervisningsbog der henvender sig til administrationsbacheloruddannelsen. Kapitlerne er inddelt efter modulerne på uddannelsen og indeholder derfor elementer af administration, forvaltning, økonomistyring, innovation, samfundsvidenskabelige metoder og politisk styrede organisationer....

  4. [Glass ceiling and slippery stairs? Gender inequalities and strategies for change in the Spanish Society of Public Health and Health Services Administration].

    Science.gov (United States)

    Colomer Revuelta, C; Peiró Pérez, R

    2002-01-01

    In scientific societies, as in other social fields, women's participation in decision making is lower than that of men. We describe the situation in SESPAS (Spanish Society of Public Health and Health Services Administration) where, despite representing a 40% of its members, very few women have been in positions in which decisions are taken or in those of professional recognition. The process of change implemented during recent years and some of the effects of the actions taken are presented. Making the existing inequalities known has generated debate and interest in the intervention. A gender and public health working group was set up. In the last two years more women have been promoted to more senior positions in SESPAS.

  5. Binary-phase compression of stretched pulses

    Science.gov (United States)

    Lozovoy, Vadim V.; Nairat, Muath; Dantus, Marcos

    2017-10-01

    Pulse stretching and compression are essential for the energy scale-up of ultrafast lasers. Here, we consider a radical approach using spectral binary phases, containing only two values (0 and π) for stretching and compressing laser pulses. We numerically explore different strategies and present results for pulse compression of factors up to a million back to the transform limit and experimentally obtain results for pulse compression of a factor of one hundred, in close agreement with numerical calculations. Imperfections resulting from binary-phase compression are addressed by considering cross-polarized wave generation filtering, and show that this approach leads to compressed pulses with contrast ratios greater than ten orders of magnitude. This new concept of binary-phase stretching and compression, if implemented in a multi-layer optic, could eliminate the need for traditional pulse stretchers and more importantly expensive compressors.

  6. Excimer Laser Pulse Compress With Pulse Feedback

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    <正>To attain a shorter laser pulse, a compressing technique called pulse feedback was developed from the saturation gain switch applied to the amplification in a discharge pumping excimer laser cavity. It can

  7. Exploration of Non-punitive Strategies for Medication Error Administration%治理用药差错的非惩罚性策略探讨

    Institute of Scientific and Technical Information of China (English)

    陈金秀; 秦玉花; 赵红卫; 张伟; 陈琪; 黄文广

    2012-01-01

    OBJECTIVE: To explore non-punitive strategies of administering medication error, and to promote safety of drug use in patients. METHODS: The traditional handling method and malpractice of medication error were analyzed, and the content of medication safety culture and countermeasures were introduced. RESULTS & CONCLUSIONS: Medication safety culture included the establishment of non-punitive share culture, and analysis of reasons for medication error but no punishment, etc. Medical personnel could report medication error and non-error event with voluntary, active, positive and true attitude; the protection of patients medication safety was maximized. A sound and effective medication error reporting system is the countermeasure of non-punitive strategies of administering medication error.%目的:探讨治理用药差错的非惩罚性策略,促进患者用药安全.方法:对用药差错的传统处理方法和弊端进行分析,介绍非惩罚性策略涉及的用药安全文化的内容及相关措施.结果:用药安全文化表现为建立无惩罚的差错分享文化、出现用药差错时重点是分析事由而不是惩罚等,促使医务人员能够自愿、主动、积极、真实地报告用药差错及非差错性事件,最大限度保护患者的用药安全;非惩罚性策略的措施即倡导建立完善、有效的用药差错报告系统.

  8. Pulsed Optics

    Science.gov (United States)

    Hirlimann, C.

    Optics is the field of physics which comprises knowledge on the interaction between light and matter. When the superposition principle can be applied to electromagnetic waves or when the properties of matter do not depend on the intensity of light, one speaks of linear optics. This situation occurs with regular light sources such as light bulbs, low-intensity light-emitting diodes and the sun. With such low-intensity sources the reaction of matter to light can be characterized by a set of parameters such as the index of refraction, the absorption and reflection coefficients and the orientation of the medium with respect to the polarization of the light. These parameters depend only on the nature of the medium. The situation changed dramatically after the development of lasers in the early sixties, which allowed the generation of light intensities larger than a kilowatt per square centimeter. Actual large-scale short-pulse lasers can generate peak powers in the petawatt regime. In that large-intensity regime the optical parameters of a material become functions of the intensity of the impinging light. In 1818 Fresnel wrote a letter to the French Academy of Sciences in which he noted that the proportionality between the vibration of the light and the subsequent vibration of matter was only true because no high intensities were available. The intensity dependence of the material response is what usually defines nonlinear optics.

  9. Database Administrator

    Science.gov (United States)

    Moore, Pam

    2010-01-01

    The Internet and electronic commerce (e-commerce) generate lots of data. Data must be stored, organized, and managed. Database administrators, or DBAs, work with database software to find ways to do this. They identify user needs, set up computer databases, and test systems. They ensure that systems perform as they should and add people to the…

  10. Database Administrator

    Science.gov (United States)

    Moore, Pam

    2010-01-01

    The Internet and electronic commerce (e-commerce) generate lots of data. Data must be stored, organized, and managed. Database administrators, or DBAs, work with database software to find ways to do this. They identify user needs, set up computer databases, and test systems. They ensure that systems perform as they should and add people to the…

  11. Centralized administrative services management.

    Science.gov (United States)

    Freed, D H

    1994-06-01

    Virtually every hospital has imposed guidelines or controls on one or more administrative service expenses. However, the actual deployment of such strategies is often voluntary, decentralized, disjointed and episodic. An alternative approach is to cluster administrative elements across hospital departments and make them the responsibility of a dedicated manager. This approach treats administrative services as an organizing principle with uniform, predictable standards of service and cost. Customer requirements for products and services are met without the need for them to physically manage that process. Materiel managers can demonstrate a leadership role by applying their professionalism and know-how to a set of products and services traditionally ignored or dealt with in an uncoordinated manner. While some initial resistance can be expected as traditional barriers are disassembled, the results should be very rewarding for the hospital and materiel manager alike.

  12. Programmable pulse generator

    CERN Document Server

    Xue Zhi Hua; Duan Xiao Hui

    2002-01-01

    The author introduces the design of programmable pulse generator that is based on a micro-controller and controlled by RS232 interface of personal computer. The whole system has good stability. The pulse generator can produce TTL pulse and analog pulse. The pulse frequency can be selected by EPLD. The voltage amplitude and pulse width of analog pulse can be adjusted by analog switches and digitally-controlled potentiometers. The software development tools of computer is National Instruments LabView5.1. The front panel of this virtual instrumentation is intuitive and easy-to-use. Parameters can be selected and changed conveniently by knob and slide

  13. A novel strategy for the treatment of chronic wounds based on the topical administration of rhEGF-loaded lipid nanoparticles: In vitro bioactivity and in vivo effectiveness in healing-impaired db/db mice.

    Science.gov (United States)

    Gainza, Garazi; Pastor, Marta; Aguirre, José Javier; Villullas, Silvia; Pedraz, José Luis; Hernandez, Rosa Maria; Igartua, Manoli

    2014-07-10

    Lipid nanoparticles are currently receiving increasing interest because they permit the topical administration of proteins, such as recombinant human epidermal growth factor (rhEGF), in a sustained and effective manner. Because chronic wounds have become a major healthcare burden, the topical administration of rhEGF-loaded lipid nanoparticles, namely solid lipid nanoparticles (SLN) and nanostructured lipid carries (NLC), appears to be an interesting and suitable strategy for the treatment of chronic wounds. Both rhEGF-loaded lipid nanoparticles were prepared through the emulsification-ultrasonication method; however, the NLC-rhEGF preparation did not require the use of any organic solvents. The characterisation of the nanoparticles (NP) revealed that the encapsulation efficiency (EE) of NLC-rhEGF was significantly greater than obtained with SLN-rhEGF. The in vitro experiments demonstrated that gamma sterilisation is a suitable process for the final sterilisation because no loss in activity was observed after the sterilisation process. In addition, the proliferation assays revealed that the bioactivity of the nanoformulations was even higher than that of free rhEGF. Finally, the effectiveness of the rhEGF-loaded lipid nanoparticles was assayed in a full-thickness wound model in db/db mice. The data demonstrated that four topical administrations of SLN-rhEGF and NLC-rhEGF significantly improved healing in terms of wound closure, restoration of the inflammatory process, and re-epithelisation grade. In addition, the data did not reveal any differences in the in vivo effectiveness between the different rhEGF-loaded lipid nanoparticles. Overall, these findings demonstrate the promising potential of rhEGF-loaded lipid nanoparticles, particularly NLC-rhEGF, for the promotion of faster and more effective healing and suggest their future application for the treatment of chronic wounds.

  14. Characterization of global metabolic profile of Zhi-Zi-Hou-Po decoction in rat bile, urine and feces after oral administration based on a strategy combining LC-MS and chemometrics.

    Science.gov (United States)

    Luo, Kaiwen; Shi, Qingshui; Feng, Fang

    2017-01-01

    Identification of metabolic profile of traditional Chinese medicine in vivo is always a challenge task. Usually, screening out and identifying the exogenous compounds manually from total ion chromatograms (TICs) of biologic samples is time-consuming and strenuous. In this study, a systematic identification strategy based on LC-MS was adopted to clarify the metabolic profiling of Zhi-Zi-Hou-Po decoction (ZZHPD) in rat. Bile, urine and feces samples of rat were obtained after oral administration and then analyzed by LC-MS after proper preparation. The xenobiotics were screened out from TICs globally and rapidly by untargeted metabolomics-driven strategy (UMDS) based on the combined of XCMS online (a web-based platform to process LC-MS data), MetAlign (a software to process LC-MS data) and SIMCA-P (a software for data analysis). Most of the xenobiotics were identified by means of series product ions filtering (sPIF), which was based on the database-hit of ZZHPD (including prototype and metabolites). Then the unmatched constituents were identified tentatively and their source and metabolic pathway were clarified by using diagnostic fragment ions strategy (DFIS). As a result, a total of 83 compounds including 44 prototype compounds and 39 metabolites were rapidly identified or tentatively characterized from the biologic samples, and among them, four of which were found for the first time. Further research on the correlations of these prototype compounds and metabolites revealed that glucuronidation is the main metabolic pathways of ZZHPD in rat bile and urine, while prototype compounds were the abundant ingredients detected in rat feces.

  15. Administrative contracts

    Directory of Open Access Journals (Sweden)

    Vukićević-Petković Milica

    2015-01-01

    Full Text Available Administrative contracts are a special type of contract where usually one of the contracting parties is a public law body and which is concluded for the performance of public service and the realization of a public interest. They go a long way since its inception to its eventual final acceptance of all the legal systems. One of the enduring characteristics of this type of contract is their disquised or unnoticed existence. This is why only monitoring their development may lead to a complete understanding of the importance and essence of this institution as well as the need for its complete legal regulation.

  16. Wide Range SET Pulse Measurement

    Science.gov (United States)

    Shuler, Robert L.; Chen, Li

    2012-01-01

    small number of SETs were not significantly higher in the test over the control circuits. At higher LET the test circuit SETs are one or two orders of magnitude greater than for the control circuit. The NFET circuit produces more and slightly longer SETs as expected. But the differences do not appear to be significant enough to modify strategies now used to avoid capture of SETs in chips such as FPGAs. Complete data and graphs will be in the full paper / presentation. In the summary figure below left, NOCL is the reference circuit without any input, and number of stages triggered is plotted. Simulation at right shows the smallest pulse captured (stage 2) at about 300 ps. Our conclusion is that the method is promising, but that improvements in the merge network are desirable before applying in a deep submicron process

  17. ALEGRA-HEDP validation strategy.

    Energy Technology Data Exchange (ETDEWEB)

    Garasi, Christopher Joseph; Mehlhorn, Thomas Alan; Trucano, Timothy Guy

    2006-01-01

    This report presents a initial validation strategy for specific SNL pulsed power program applications of the ALEGRA-HEDP radiation-magnetohydrodynamics computer code. The strategy is written to be (1) broadened and deepened with future evolution of particular specifications given in this version; (2) broadly applicable to computational capabilities other than ALEGRA-HEDP directed at the same pulsed power applications. The content and applicability of the document are highly constrained by the R&D thrust of the SNL pulsed power program. This means that the strategy has significant gaps, indicative of the flexibility required to respond to an ongoing experimental program that is heavily engaged in phenomena discovery.

  18. Miniature, Rugged, Pulsed Laser Source for LIDAR Application Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Princeton Optronics proposes to develop a high energy pulsed laser source based on a novel approach. The approach consists of a technique to combine a large number...

  19. Propellant Conditioning Using Improved Pulse Tube Cryocooler Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Application of the proposed technology (an affordable, large-scale, high-efficiency, low-temperature pulse tube cryocooler system), serves two NASA needs: an...

  20. Pulsed Electrogasdynamic Thruster for Attitude Control and Orbit Maneuver Project

    Data.gov (United States)

    National Aeronautics and Space Administration — In the Phase I program we successfully demonstrated the feasibility of the Pulsed ElectroGasdynamic (PEG) thruster for attitude control and orbital maneuvering. In...

  1. 20 W High Efficiency 1550 nm Pulsed Fiber Laser Project

    Data.gov (United States)

    National Aeronautics and Space Administration — High peak power short pulsed lasers have been considered to be an enabling technology to build high power transmitters for future deep space high rate space...

  2. Pulsed Green Laser for Time Resolved Raman Spectroscopy Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This SBIR Phase I effort will demonstrate the feasibility of developing a fully packaged, efficient, short pulse, high repetition rate frequency doubled micro-chip...

  3. ADMINISTRATIVE CIRCULARS

    CERN Multimedia

    Division des ressources humaines

    2000-01-01

    N° 2 (Rev. 1) - March 2000Guidelines and procedures concerning recruitment and probation period of staff membersN° 9 (Rev. 2) - March 2000Staff members contractsN° 16 (Rev. 2) - January 2000TrainingN° 30 (Rev. 1) - January 2000Indemnities and reimbursements upon taking up appointment and termination of contractN° 32 - February 2000Principles and procedures governing complaints of harassmentThese circular have been amended (No 2, N° 9, N° 16 and N° 30) or drawn up (N° 32).Copies are available in the Divisional Secretariats.Note:\tAdministrative and operational circulars, as well as the lists of those in force, are available for consultation in the server SRV4_Home in the Appletalk zone NOVELL (as GUEST or using your Novell username and password), volume PE Division Data Disk.The Word files are available in the folder COM, folder Public, folder ADM.CIRC.docHuman Resources DivisionTel. 74128

  4. Radial pulse (image)

    Science.gov (United States)

    ... heart. The arteries are the vessels with the "pulse", a rhythmic pushing of the blood in the ... a refilling of the heart chamber. To determine heart rate, one feels the beats at a pulse point ...

  5. Wrist pulse (image)

    Science.gov (United States)

    To measure the pulse at the wrist, place the index and middle finger over the underside of the opposite wrist, below the base ... firmly with flat fingers until you feel the pulse in the radial artery.

  6. Asia -Pacific Strategy of Obama Administration and Its Impact on Sino -US Relations%刍议奥巴马政府的亚太战略及对中美关系的影响

    Institute of Scientific and Technical Information of China (English)

    陈友骏

    2012-01-01

    After the global financial crisis, the position of Asia - Pacific region in the global political and eco- nomic structure upgrades rapidly. The Obama administration pays great attention on adjusting the Asia - Pacific strategy in America' s global strategy since it took power. After careful and detailed operation in the past three years, the Asia - Pacific strategy of Obama administration has been shaped fundamentally, which deeply influences the international pattern, the Asia - Pacific regional situation and the balance of big powers' relations. More impor- tantly, this strategy triggers a series of new contradictions in Asia -Pacific region and handicaps China' s diplomat- ic relations inside this region. However, the friendly - cooperated and overall win - win relationship between China and US is not destroyed. To maintain the peace and stability in the Asia - Pacific region is still common responsibil- ity of the two great powers which are the main forces in the Asia - Pacific region. The urgent task for the develop- ment of Sino - US relations is to confirm certain new strategic foundation for their further cooperation with "great wisdom".%全球性金融危机之后,亚太地区在全球政治经济格局的地位急速跃升。美国奥巴马政府一上台,就极为重视调整亚太战略在美国全球战略中的核心地位。经过近三年的缜密部署和细致经营,奥巴马政府的亚太战略已基本构建成型,对国际格局的进一步调整、亚太地区的局势新发展、大国关系的平衡等均产生深刻影响。更为重要的是,奥巴马政府亚太战略的调整引发一系列亚太地区新矛盾的产生,并对我发展亚太地区的周边外交关系形成掣肘。但是,中美之间友好合作、互利共赢的总体局面并未打破,维护亚太地区的和平与稳定仍是中、美两个大国作为亚太地区主要力量的共同责任,现阶段的紧迫任务就是要用"大智慧"为中美关

  7. Force Filed Analysis of the Administrative Examination and Approval System Reform in China and Breakthrough Strategies%我国行政审批制度改革的力场分析与突破策略

    Institute of Scientific and Technical Information of China (English)

    李青萍

    2014-01-01

    Administrative examination and approval is a prepositive management tool used by the government to allocate the market and social resources .In order to build an approval system w hich can be compatible with socialist market economy ,decision-makers intend to reach this goal by reducing projects ,standardizing approval procedures , achieving system innovation and promoting law-based administration .According to the force filed analysis theory ,there is driving force and restraining force in the process of administrative examination and approval system reform due to the redistribution of interests to those related subjects .By analyzing the interest orientation of decision makers ,executives , subjects to regulatory and consumers can we know the strength of the driving force and restraining force ,and also we can calculate the direction of the institutional transition .For the sake of making the reform be implemented smoothly ,it is also important to understand the presence of the restraining forces and to seek appropriate strategies for breakthroughs .%行政审批是政府对市场和社会资源进行配置的前置性管理手段。为了与社会主义市场经济体制相匹配,我国在行政审批改革中设立了减少审批项目、规范审批行为、实现制度创新和推进依法行政的改革目标。但根据力场分析理论,在行政审批制度改革过程中由于对相关主体利益的重新分配造成改革力场中存在驱动力和制约力。通过研究改革中决策者、执行者、受规制者和消费者的利益取向,可以获知驱动力和制约力的强弱,并推算出制度变迁的方向。为了使行政审批制度改革能够顺利推行,还需进一步分析制约力存在的方式并寻求相应的突破策略。

  8. Pulse-Width Jitter Measurement for Laser Diode Pulses

    Institute of Scientific and Technical Information of China (English)

    TANG Jun-Hua; WANG Yun-Cai

    2006-01-01

    @@ Theoretical analysis and experimental measurement of pulse-width jitter of diode laser pulses are presented. The expression of pulse power spectra with all amplitude jitter, timing jitter and pulse-width jitter is deduced.

  9. An Automatic Calculation Method for the Triggering Strategy of the Capacitive Pulsed-Power Supply%电容储能型脉冲电源分时分段触发策略自动计算方法

    Institute of Scientific and Technical Information of China (English)

    刘旭堃; 于歆杰; 刘秀成

    2016-01-01

    Based on Matlab platform,a fast solving method for the launch process of the electromagnetic railgun is proposed. By using this method,an automatic calculation method for the triggering strategy of the capacitive pulsed-power supply is then proposed, which possesses the advantages of both accuracy and applicability. The circuit model of the electromagnetic railgun system is firstly analyzed and the mathematical expressions of the relevant electrical and mechanical quantities are also given. Then the time discretization idea, the circuit decoupling idea and the specific implementation of the fast solving method are elaborated in detail. And the basic principle and the specific implementation of the automatic calculation method are also discussed. Finally,a typically representative system with 4 MJ initial energy is given. The feasibility and accuracy of these two methods are proven through the comparison with the Simplorer simulation results which are confirmed to be compliant with the real system. Results show that the rail current waveform is approximate to a flat wave under the action of the triggering strategy acquired from the automatic calculation method,and the relative error of the armature launch velocity between the Simplorer simulation result and the Matlab calculation result is within 3%. These results confirm the feasibility and accuracy of the above methods.%提出一种基于Matlab数值计算平台、针对电磁轨道炮发射过程的快速求解方法,并以此为基础提出一种兼具准确性和普适性、针对电容储能型脉冲电源分时分段触发策略的自动计算方法。首先给出电磁轨道炮的电路模型,给出发射过程中各机电物理量的表达式;其次阐述发射过程求解方法所采用的离散时间步长思想、电源负载解耦思想和具体实现方法;进而阐述触发策略的确定依据和计算方法的具体实现;最后以一个具有典型代表性、初始储能为4 MJ的系统

  10. Ceramic dentures manufactured with ultrashort laser pulses

    Science.gov (United States)

    Werelius, Kristian; Weigl, Paul

    2004-06-01

    Conventional manufacturing of individual ceramic dental prosthesis implies a handmade metallic framework, which is then veneered with ceramic layers. In order to manufacture all-ceramic dental prosthesis a CAD/CAM system is necessary due to the three dimensional shaping of high strength ceramics. Most CAD/CAM systems presently grind blocks of ceramic after the construction process in order to create the prosthesis. Using high-strength ceramics, such as Hot Isostatic Pressed (HIP)-zirconia, this is limited to copings. Anatomically shaped fixed dentures have a sculptured surface with small details, which can't be created by existing grinding tools. This procedure is also time consuming and subject to significant loss in mechanical strength and thus reduced survival rate once inserted. Ultra-short laser pulses offer a possibility in machining highly complex sculptured surfaces out of high-strength ceramic with negligible damage to the surface and bulk of the ceramic. In order to determine efficiency, quality and damage, several laser ablation parameters such as pulse duration, pulse energy and ablation strategies were studied. The maximum ablation rate was found using 400 fs at high pulse energies. High pulse energies such as 200μJ were used with low damage in mechanical strength compared to grinding. Due to the limitation of available laser systems in pulse repetition rates and power, the use of special ablation strategies provide a possibility to manufacture fully ceramic dental prosthesis efficiently.

  11. Proceedings of Pulsed Magnet Design and Measurement Workshop

    Energy Technology Data Exchange (ETDEWEB)

    Shaftan, T.; Heese, R.; Ozaki,S.

    2010-01-19

    The goals of the Workshop are to assess the design of pulsed system at the NSLS-II and establish mitigation strategies for critical issues during development. The focus of the Workshop is on resolving questions related to the set-up of the pulsed magnet laboratory, on measuring the pulsed magnet's current waveforms and fields, and on achieving tight tolerances on the magnet's alignment and field quality.

  12. Ultrafast X-ray pulse measurement method

    CERN Document Server

    Geloni, Gianluca; Saldin, Evgeni

    2010-01-01

    In this paper we describe a measurement technique capable of resolving femtosecond X-ray pulses from XFEL facilities. Since these ultrashort pulses are themselves the shortest event available, our measurement strategy is to let the X-ray pulse sample itself. Our method relies on the application of a "fresh" bunch technique, which allows for the production of a seeded X-ray pulse with a variable delay between seed and electron bunch. The shot-to-shot averaged energy per pulse is recorded. It turns out that one actually measures the autocorrelation function of the X-ray pulse, which is related in a simple way to the actual pulse width. For implementation of the proposed technique, it is sufficient to substitute a single undulator segment with a short magnetic chicane. The focusing system of the undulator remains untouched, and the installation does not perturb the baseline mode of operation. We present a feasibility study and we make exemplifications with typical parameters of an X-ray FEL.

  13. A High Efficiency 1kWatt GaN Amplifier for P-Band Pulsed Applications Project

    Data.gov (United States)

    National Aeronautics and Space Administration — An improved efficiency amplifier for high power pulse applications at P-Band will be investigated that will support space based RADAR systems. Current P-Band pulsed...

  14. A High Efficiency 1kWatt GaN amplifier for P-Band pulsed applications Project

    Data.gov (United States)

    National Aeronautics and Space Administration — An improved efficiency amplifier for high power pulse applications at P-Band will be investigated that will support space based RADAR systems. Current P-Band pulsed...

  15. 77 FR 37573 - Effective Date of Requirement for Premarket Approval for an Implantable Pacemaker Pulse Generator

    Science.gov (United States)

    2012-06-22

    ... Approval for an Implantable Pacemaker Pulse Generator AGENCY: Food and Drug Administration, HHS. ACTION... protocol (PDP) for implantable pacemaker pulse generators. The Agency has summarized its findings regarding... PMA or notice of completion of a PDP for the implantable pacemaker pulse generator. In accordance...

  16. Limited sampling strategies for tacrolimus exposure (AUC0-24) prediction after Prograf(®) and Advagraf(®) administration in children and adolescents with liver or kidney transplants.

    Science.gov (United States)

    Almeida-Paulo, Gonzalo N; Lubomirov, Rubin; Alonso-Sanchez, Nazareth Laura; Espinosa-Román, Laura; Fernández Camblor, Carlota; Díaz, Carmen; Muñoz Bartola, Gema; Carcas-Sansuán, Antonio J

    2014-09-01

    To develop limited sampling strategies (LSSs) to predict total tacrolimus exposure (AUC0-24 ) after the administration of Advagraf(®) and Prograf(®) (Astellas Pharma S.A, Madrid, Spain) to pediatric patients with stable liver or kidney transplants. Forty-one pharmacokinetic profiles were obtained after Prograf(®) and Advagraf(®) administration. LSSs predicting AUC0-24 were developed by linear regression using three extraction time points. Selection of the most accurate LSS was made based on the r(2) , mean error, and mean absolute error. All selected LSSs had higher correlation with AUC0-24 than the correlation found between C0 and AUC0-24 . Best LSS for Prograf(®) in liver transplants was C0_1.5_4 (r(2)  = 0.939) and for kidney transplants C0_1_3 (r(2)  = 0.925). For Advagraf(®) , the best LSS in liver transplants was C0_1_2.5 (r(2)  = 0.938) and for kidney transplants was C0_0.5_4 (r(2)  = 0.931). Excluding transplant type variable, the best LSS for Prograf(®) is C0-1-3 (r(2)  = 0.920) and the best LSS for Advagraf(®) was C0_0.5_4 (r(2)  = 0.926). Considering transplant type irrespective of the formulation used, the best LSS for liver transplants was C0_2_3 (r(2)  = 0.913) and for kidney transplants was C0_0.5_4 (r(2)  = 0.898). Best LSS, considering all data together, was C0_1_4 (r(2)  = 0.898). We developed several LSSs to predict AUC0-24 for tacrolimus in children and adolescents with kidney or liver transplants after Prograf(®) and/or Advagraf(®) treatment.

  17. Intracerebroventricular administration of drugs.

    Science.gov (United States)

    Cook, Aaron M; Mieure, Katherine D; Owen, Robert D; Pesaturo, Adam B; Hatton, Jimmi

    2009-07-01

    Intracerebroventricular drug administration is a method that bypasses the blood-brain barrier and other mechanisms that limit drug distribution into the brain, allowing high drug concentrations to enter the central compartment. Instillation of drugs directly into the ventricles of the brain must be done carefully and with full consideration of factors affecting the efficacy and safety of this route of administration. These factors include the osmolarity, pH, volume, and presence of preservatives and diluents of the drug solution being administered. Very few studies have formally investigated intraventricular therapies, and dosing recommendations may vary widely depending on the agent and the patient. Many antimicrobials have been given intraventricularly, although very few prospective studies have evaluated this strategy. There are wide variations among the reports regarding dosage regimens and the pharmacokinetics of the antimicrobials used. Guidance on appropriate formulations and their use is lacking. Clinicians should be aware of their patients' ongoing disease processes and neurologic status, as well as pertinent physiochemical properties of drugs when formulating them for intracerebroventricular administration; a high index of suspicion should be maintained when monitoring patients for adverse drug events after instillation.

  18. The Citizens’E-participation in Administrative Accountability:Problems, Reasons and Development Strategies%行政问责中的公民电子参与:问题、症因与对策

    Institute of Scientific and Technical Information of China (English)

    李科利; 梁丽芝

    2016-01-01

    公民电子参与行政问责是互联网时代实现公民权的新渠道。目前我国公民电子参与行政问责存在着以下几个问题:问责效果取决于被问责事件的舆论关注度,而非事件本身;问责动机更多出于个人目标,而非公共目标;问责行为带有一定的随意性,而非严肃性。这些问题的存在可以从制度层面、文化层面、技术层面寻求原因。制度层面主要是体制内制度化的公民问责渠道不通畅、体制外的公民电子参与行政问责的法律制度滞后;文化层面主要是政府责任意识缺失、公民电子参与理性不足;技术层面主要是我国电子政务所采用的现有信息与通讯技术还无法有效应对公民的多元化需求、信息的交互性和可扩展性、信息安全、数字鸿沟等问题。本文相应地从制度建设、公民意识培育、采用先进的参与技术完善公民电子参与机制等方面提出解决对策。%Citizens’E-participation in administrative accountability is a new channel to achieve citizenship in the Internet era. There are several major problems about citizens’E-participation in administrative accountability in China currently:accountability effect depends on the public attention of the event being accountable,rather than the event itself;accountability motivated more by personal goals rather than the public purpose;accountability acts with a certain arbitrariness rather than the seriousness. The reason mainly depends on institutional factors which the institutionalized channel about citizen accountability within the system is not smooth and the legal system about the citizen E-participation administrative accountability outside the system is lag;on cultural factors which the govern-ment sense of responsibility and the rationality of citizen E-participation is relatively lack on technical factors which information and communication technology still face difficulties dealing with

  19. High voltage pulse electron beam control strategy and influence on weld bead shape%高压脉冲电子束的控制及其对焊缝形貌影响

    Institute of Scientific and Technical Information of China (English)

    许海鹰; 余伟; 左从进

    2011-01-01

    研制出一台150 kV/30 kW高压脉冲电子束焊机,介绍了控制脉冲束流产生的偏压脉冲电源拓扑电路结构及脉冲束流频率、占空比、束流基值、束流峰值的调节控制技术.在0~1 kHz频率范围内,该电源可输出最大幅值200 mA的脉冲电子束束流,且工艺参数调节方便.分别采用脉冲束流与连续束流电子束工艺焊接了1Cr18Ni9Ti奥氏体不锈钢,对不同工艺的焊缝形貌进行了对比分析.与连续束流电子束焊接工艺相比,采用脉冲电子束焊接工艺的焊缝熔深增加,深宽比增大;对于脉冲电子束焊接工艺,占空比给定时,随着束流频率增加,焊接缺陷减少.试验结果表明:脉冲束流频率、占空比是影响焊缝成形的关键工艺参数;脉冲调制方式控制偏压是获得高压脉冲电子束的理想控制技术之一.%A 150 kV/30 kW high voltage pulse electron beam welding power source was developed.The bias pulse power source topology and control technique about base beam current,peak beam current,pulse beam duty,pulse beam frequency were introduced.Not only the biggest peak beam current up to 200 mA has been exported by this power source at 0-1 kHz,but also weld technology parameters are expediently adjusted.The 1Cr18Ni9Ti stainless steel work pieces had been welded by electron beam welding and pulse electron beam welding.These weld bead shapes had been studied and analyzed.In contrast with electron beam welding,weld penetration will be increased by pulse electron beam welding introduced.At the immovable pulse beam duty,the weld faults will be reduced with the pulse beam frequency being increased.Through these weld tests,besides beam frequency and duty are substantiated key technique parameters for weld shapes,it also shows that pulse modulated bias power source technique is an applicable technology to achieve high voltage pulse electron beam.

  20. Administration of Anesthesia

    Science.gov (United States)

    ... a Surgeon What We Do Administration of Anesthesia Administration of Anesthesia Oral and maxillofacial surgeons are extensively ... Injury Wisdom Teeth Management Procedures Administration of Anesthesia Administration of Anesthesia Oral and maxillofacial surgeons are extensively ...

  1. Chirped Pulse Microwave Spectroscopy in Pulsed Uniform Supersonic Flows

    Science.gov (United States)

    Abeysekera, Chamara; Oldham, James; Prozument, Kirill; Joalland, Baptiste; Park, Barratt; Field, Robert W.; Sims, Ian; Suits, Arthur; Zack, Lindsay

    2014-06-01

    We present preliminary results describing the development of a new instrument that combines two powerful techniques: Chirped Pulse-Fourier Transform MicroWave (CP-FTMW) spectroscopy and pulsed uniform supersonic flows. It promises a nearly universal detection method that can deliver quantitative isomer, conformer, and vibrational level specific detection, characterization of unstable reaction products and intermediates and perform unique spectroscopic, kinetics and dynamics measurements. We have constructed a new high-power K_a-band, 26-40 GHz, chirped pulse spectrometer with sub-MHz resolution, analogous to the revolutionary CP-FTMW spectroscopic technique developed in the Pate group at University of Virginia. In order to study smaller molecules, the E-band, 60-90 GHz, CP capability was added to our spectrometer. A novel strategy for generating uniform supersonic flow through a Laval nozzle is introduced. High throughput pulsed piezo-valve is used to produce cold (30 K) uniform flow with large volumes of 150 cm^3 and densities of 1014 molecules/cm3 with modest pumping facilities. The uniform flow conditions for a variety of noble gases extend as far as 20 cm from the Laval nozzle and a single compound turbo-molecular pump maintains the operating pressure. Two competing design considerations are critical to the performance of the system: a low temperature flow is needed to maximize the population difference between rotational levels, and high gas number densities are needed to ensure rapid cooling to achieve the uniform flow conditions. At the same time, collision times shorter than the chirp duration will give inaccurate intensities and reduced signal levels due to collisional dephasing of free induction decay. Details of the instrument and future directions and challenges will be discussed.

  2. PulseSoar

    Energy Technology Data Exchange (ETDEWEB)

    Carter, P.; Peglow, S.

    1992-07-21

    This paper is an introduction to the PulseSoar concept. PulseSoar is a hypervelocity airplane that uses existing airport facilities and current technologies to fly at the very edge of space. It will be shown that PulseSoar can fly between any two points on the globe in less than two hours with fuel efficiency exceeding current state of the art commercial airliners. In addition, it will be shown that PulseSoar avoids environmental issues concerning the ozone layer and sonic booms because of its unique flight profile. All of this can be achieved with current technology. PulseSoar does not require the development of enabling technology. It is a concept which can be demonstrated today. The importance of this idea goes beyond the technical significance`s of PulseSoar in terms of feasibility and performance. PulseSoar could provide a crucial economic advantage to America`s largest export market: commercial aircraft. PulseSoar is a breakthrough concept for addressing the emerging markets of long range and high speed aircraft. Application of PulseSoar to commercial transport could provide the US Aerospace industry a substantial lead in offering high speed/long range aircraft to the world`s airlines. The rapid emergence of a US developed high speed aircraft could also be important to our competitiveness in the Pacific Rim and South American economies. A quick and inexpensive demonstration vehicle is proposed to bang the concept to reality within two years. This discussion will address all the major technical subjects encompassed by PulseSoar and identifies several near-term, and low risk, applications which may be further explored with the initial demonstration vehicle. What is PulseSoar? PulseSoar could enable high speed, high altitude and long range flight without many of the difficulties encountered by traditional hypersonic vehicles.

  3. Pulse Tube Refrigerator

    Science.gov (United States)

    Matsubara, Yoichi

    The pulse tube refrigerator is one of the regenerative cycle refrigerators such as Stirling cycle or Gifford-McMahon cycle which gives the cooling temperature below 150 K down to liquid helium temperature. In 1963, W. E. Gifford invented a simple refrigeration cycle which is composed of compressor, regenerator and simple tube named as pulse tube which gives a similar function of the expander in Stirling or Gifford-McMahon cycle. The thermodynamically performance of this pulse tube refrigerator is inferior to that of other regenerative cycles. In 1984, however, Mikulin and coworkers made a significant advance in pulse tube configuration called as orifice pulse tube. After this, several modifications of the pulse tube hot end configuration have been developed. With those modifications, the thermodynamic performance of the pulse tube refrigerator became the same order to that of Stirling and Gifford-McMahon refrigerator. This article reviews the brief history of the pulse tube refrigerator development in the view point of its thermodynamically efficiency. Simplified theories of the energy flow in the pulse tube have also been described.

  4. Ultrashort Laser Pulse Phenomena

    CERN Document Server

    Diels, Jean-Claude

    2006-01-01

    Ultrashort Laser Pulse Phenomena, 2e serves as an introduction to the phenomena of ultra short laser pulses and describes how this technology can be used to examine problems in areas such as electromagnetism, optics, and quantum mechanics. Ultrashort Laser Pulse Phenomena combines theoretical backgrounds and experimental techniques and will serve as a manual on designing and constructing femtosecond (""faster than electronics"") systems or experiments from scratch. Beyond the simple optical system, the various sources of ultrashort pulses are presented, again with emphasis on the basic

  5. AN SEIRS EPIDEMIC MODEL WITH TWO DELAYS AND PULSE VACCINATION

    Institute of Scientific and Technical Information of China (English)

    Jianjun JIAO; Lansun CHEN; Shaohong CAI

    2008-01-01

    Pulse vaccination is an effective and important strategy to eradicate an infectious disease. The authors investigate an SEIRS epidemic model with two delays and pulse vaccination. By using the discrete dynamical system determined by stroboscopic map, the authors obtain that the infectious population dies out if RΔ <1, and the infectious population is uniformly persistent if RΔ >1. The results indicate that a short period of pulse vaccination or a large pulse vaccination rate is a sufficient condition to eradicate the disease.

  6. Advances in library administration and organization

    CERN Document Server

    Williams, Delmus E; Sweeney, Jennifer K

    2015-01-01

    Volume 33 of Advances in Library Administration and Organization brings together a range of diverse and reflective essays to provide strategies that will be of value in addressing challenges faced by current and future library managers.

  7. Sichuan Petroleum Administration Strives for World Cooperation

    Institute of Scientific and Technical Information of China (English)

    Xiao Dengming; Wang Zong

    1997-01-01

    @@ Located in the "Paradise" Sichuan Province, with strategies of cooperation with foreign firms and diversified development,Sichuan Petroleum Administration (SPA)stretches toward the worldwide markets,which enforces continuously the company's overall capabilities.

  8. Pulsed Plasma Electron Sources

    Science.gov (United States)

    Krasik, Yakov

    2008-11-01

    Pulsed (˜10-7 s) electron beams with high current density (>10^2 A/cm^2) are generated in diodes with electric field of E > 10^6 V/cm. The source of electrons in these diodes is explosive emission plasma, which limits pulse duration; in the case E Hadas and Ya. E. Krasik, Europhysics Lett. 82, 55001 (2008).

  9. PULSE AMPLITUDE DISTRIBUTION RECORDER

    Science.gov (United States)

    Cowper, G.

    1958-08-12

    A device is described for automatica1ly recording pulse annplitude distribution received from a counter. The novelty of the device consists of the over-all arrangement of conventional circuit elements to provide an easy to read permanent record of the pulse amplitude distribution during a certain time period. In the device a pulse analyzer separates the pulses according to annplitude into several channels. A scaler in each channel counts the pulses and operates a pen marker positioned over a drivable recorder sheet. Since the scalers in each channel have the sanne capacity, the control circuitry permits counting of the incoming pulses until one scaler reaches capacity, whereupon the input is removed and an internal oscillator supplies the necessary pulses to fill up the other scalers. Movement of the chart sheet is initiated wben the first scaler reaches capacity to thereby give a series of marks at spacings proportional to the time required to fill the remaining scalers, and accessory equipment marks calibration points on the recorder sheet to facilitate direct reading of the number of external pulses supplied to each scaler.

  10. Environmental Education Strategy

    Science.gov (United States)

    Bootrach, Pradit; Thiengkamol, Nongnapas; Thiengkamol, Tanarat Khoowaranyoo

    2015-01-01

    Data was collected from 403 primary school administrators in Maha Sarakham Province, Thailand, to develop causal relationship model of Administrator Characteristics (AC), Teacher Characteristics (TC) and Environmental Education Principle (EE) that affect Environmental Education Strategy (EES) through Inspiration of Public Mind for Environmental…

  11. Environmental Education Strategy

    Science.gov (United States)

    Bootrach, Pradit; Thiengkamol, Nongnapas; Thiengkamol, Tanarat Khoowaranyoo

    2015-01-01

    Data was collected from 403 primary school administrators in Maha Sarakham Province, Thailand, to develop causal relationship model of Administrator Characteristics (AC), Teacher Characteristics (TC) and Environmental Education Principle (EE) that affect Environmental Education Strategy (EES) through Inspiration of Public Mind for Environmental…

  12. 二极管钳位式三电平逆变器SVPWM控制策略研究%Control Strategy Study of Diode-Clamp Three-Level Inverter Based on Space Vector Pulse Width Modulation

    Institute of Scientific and Technical Information of China (English)

    张佩炯

    2011-01-01

    空间矢量脉宽调制在多电平逆变器的控制中应用广泛,但是随着电平数增加,控制算法渐趋复杂化。提出了三电平空间矢量脉宽调制控制方法,将三电平电压矢量区变换为由两电平空间矢量区构成,从而通过使用两电平空间矢量脉宽调制方法简化了控制算法。该方法理论上可应用于更高电平逆变器的控制中,仿真验证了方法的可行性。%Space vector pulse width modulation is widely applied in control of multi-level inverters, but following increasing of level number, the control algorithm becomes more and more complicated. Three-level space vector pulse width modulation control method was raised to transfer three-level voltage vector zone to two-level space vector zones, so as to simplify the control algorithm with two-level space vector pulse modulation method. The method on the theory can be used to control much higher level inverters and simulation has verified feasibility of the method.

  13. Pulsed electron beam precharger

    Energy Technology Data Exchange (ETDEWEB)

    Finney, W.C. (ed.); Shelton, W.N.

    1990-01-01

    Florida State University is investigating the concept of pulsed electron beams for fly ash precipitation. This report describes the results and data on three of the subtasks of this project and preliminary work only on the remaining five subtasks. Described are the modification of precharger for pulsed and DC energization of anode; installation of the Q/A measurement system; and modification and installation of pulsed power supply to provide both pulsed and DC energization of the anode. The other tasks include: measurement of the removal efficiency for monodisperse simulated fly ash particles; measurement of particle charge; optimization of pulse energization schedule for maximum removal efficiency; practical assessment of results; and measurement of the removal efficiency for polydisperse test particles. 15 figs., 1 tab. (CK)

  14. Senior Administrators Should Have Administrative Contracts.

    Science.gov (United States)

    Posner, Gary J.

    1987-01-01

    Recognizing that termination is viewed by the employee as the equivalent to capital punishment of a career, an administrative contract can reduce the emotional and financial entanglements that often result. Administrative contracts are described. (MLW)

  15. Pulse Combustors—Performance and Control

    Institute of Scientific and Technical Information of China (English)

    MichaelZeutzius; ToshiakiSetoguchi; 等

    2000-01-01

    Limited resources of fossil energy require the search for new energy conversion preocesses and the increase of the efficiency of power plants to ensure the energy household in the future,Basically,changing the combustion mode from steady to pulse combustion makes an enormous reduction of fuel consumption possible,Active control systems for pulse combustors installed into the inlet further improve the efficiency and extend the operating range considerably.The control algorithm including fuel rate-air rate-pressure characteristics and control strategies as well are presented.

  16. Pulse Distortion in Saturated Fiber Optical Parametric Chirped Pulse Amplification

    DEFF Research Database (Denmark)

    Lali-Dastjerdi, Zohreh; Da Ros, Francesco; Rottwitt, Karsten

    2012-01-01

    Fiber optical parametric chirped pulse amplification is experimentally compared for different chirped pulses in the picosecond regime. The amplified chirped pulses show distortion appearing as pedestals after recompression when the amplifier is operated in saturation.......Fiber optical parametric chirped pulse amplification is experimentally compared for different chirped pulses in the picosecond regime. The amplified chirped pulses show distortion appearing as pedestals after recompression when the amplifier is operated in saturation....

  17. Korean Peninsula Policy of Medvedev’ s Administration under Its Asia-Pacific Strategy%梅德韦杰夫政府亚太战略下的朝鲜半岛政策分析

    Institute of Scientific and Technical Information of China (English)

    徐博; 刘清才

    2011-01-01

    梅德韦杰夫在成为俄罗斯总统后,十分重视发展与亚太地区国家的关系,并多次强调面向亚太地区的外交是俄罗斯对外政策的优先方向之一。朝鲜半岛在梅德韦杰夫政府的整个亚太战略中具有十分特殊的地位,是其整个亚太战略下的重要组成部分。梅德韦杰夫自2008年5月成为俄罗斯总统以来,其半岛政策在很大程度继承了普京政府时期俄半岛政策的实用主义方针,即在维护半岛局势总体稳定的同时争取在朝鲜半岛问题上提高俄罗斯的话语权。但面对朝鲜半岛不断变化的复杂形势,梅德韦杰夫政府的半岛政策也在体现出与普京时期不同的地方。从总体上看,加强经济合作成为了梅德韦杰夫政府对朝鲜半岛政策的主要调整点,而扩大能源合作则成为梅德韦杰夫政府朝鲜半岛政策的主要亮点。%Medvedev has thought highly of the relationship of Russia with the countries in Asia-Pacific area since his assumption of the president of Russia.He stressed for several times that the diplomacy toward Asia-Pacific area is the prior orientation of Russia’ s foreign policy.Korean peninsula plays a special and important role in the Asia-Pacific strategy of Medvedev’ s administration.To a great extent,the present policy toward Korean peninsula of Russia continues the pragmatism policy of Putin’ s administration,that is,Russia will raise its discourse power on issues related to Korean Peninsula while maintaining an overall stable situation in that area.But there are some amendments in light of the ever changing situation in that region.In general,the major adjustment is that Medvedev wants to strengthen the economic cooperation with Korean Peninsula,and he highlights the extensive energy cooperation with the two Koreas.

  18. 基于医护培训管理信息化的电子教务策略探讨%Exploration of Strategy for Digital Education Based on Informatics Administration of Medical Training Application

    Institute of Scientific and Technical Information of China (English)

    陈小清; 刘嘉眉; 彭鳒侨; 刘宇平

    2014-01-01

    Objective: To develop a Medical training system for administration so as to realize informatics decision. Methods:After hardware ready, messages are passed on Servlets driven by Java, Oracle database is searchable by connection of JDBC bridge, it was attempted to execute on web interface of localhost:8080 individually. Result:According to the produce of Requirement, planning, design, implementation, testing & maintenance, a reasonable management engine was set up initially based on valuable practice, available to bilingual search in Chinese-English for oversea training opportunities, it is compatible of functions Register, Login, Apply, Pre-train acknowledge, On-train evaluation, Post-train assessment, applicants' information are listed onto database for Human Resource Department to totally control including modules of Create、View、Insert, Select, Update and Delete. This system is able to grade scores by standard criteria and employees' resume input, and auto-calculate quantitative qualification of each candidate and generally prior sequence in order to publish competitive positions. Besides, we brought in secure setting of Logon permission、Authority distribution、Source protection、Secure policy to ensure Training program running successfully. Conclusion:This strategy for digital education and maintenance of secure setting will extend the technologic touch of a company or an individual, simplify and consummate the application process, present its fairness and equity of selection, and thus improve administrative efficiency greatly.%目的:开发“医护培训管理系统”,实现信息化决策。方法:在硬件齐全的基础上,以Java驱动Servlets传递信息,由JDBC搭桥贯穿可供检索的Oracle数据库,在localhost:8080的Web界面上尝试单机运行。结果:按照“明细、计划、设计、实现、测试、维护”等步骤,在保持功能实现的前提下初步建立合理化的管理引擎,提供海外进修岗

  19. Ciática: tratamiento con ozono intradiscal y radiofrecuencia del ganglio de la raíz dorsal frente a cada una de estas dos técnicas Sciatica: intradiscal ozone administration associated with pulsed radiofrequency of the dorsal root ganglia compared with the isolated use of each of these two techniques

    Directory of Open Access Journals (Sweden)

    L. Cánovas

    2009-04-01

    Full Text Available Objetivo: Estudio prospectivo y comparativo que compara la eficacia de la administración intradiscal de ozono asociada a radiofrecuencia pulsada de la raíz lumbar comprometida con cada una de estas 2 técnicas, de forma aislada, en el tratamiento del dolor radicular secundario a hernia discal. Material y método: Se incluyó en el estudio a 30 pacientes con clínica de dolor lumbar severo, escala visual analógica (EVA > 6, de más de 3 meses de duración, resistente al tratamiento conservador (medicación oral y fármacos epidurales, con signos de afectación radicular con o sin parestesia e hipoestesia y con distribución correspondiente al dermatoma afectado. Los criterios radiológicos de inclusión fueron: evidencia en la resonancia magnética (RM de hernia discal contenida con o sin degeneración discal. Los pacientes se distribuyeron aleatoriamente en 3 grupos: grupo A (5-15 ml de ozono intradiscal a 27 mg/ml de concentración y radiofrecuencia pulsada del ganglio de la raíz dorsal correspondiente; grupo B (5-15 ml de ozono intradiscal a 27 mg/ml de concentración y grupo C (radiofrecuencia pulsada del ganglio de la raíz dorsal al nivel comprometido. La eficacia analgésica se valoró a los 15 días, al mes, y a los 3 y 6 meses de la técnica, mediante EVA y se llevó a cabo una valoración radiológica con RM a los 3 meses. El estudio estadístico se realizó mediante el programa SPSS 14.0 para Windows. Se consideró significativa una p Objective: We performed a prospective, comparative study that evaluated the effectiveness of intradiscal ozone administration associated with pulsed radiofrequency of the compromised lumbar root versus the isolated use of each of these two techniques in the management of radicular pain secondary to a herniated disc. Materials and method: The study included 30 patients with severe back pain, visual analog scale (VAS > 6 and onset more than 3 months previously, who were resistant to conservative

  20. Current status of hand-washing compliance of medical staffs in grass-root hospitals and administration strategies%基层医院医护人员洗手依从性现状及管理措施

    Institute of Scientific and Technical Information of China (English)

    孔双红

    2012-01-01

    目的 调查医院医护人员手卫生及洗手依从性现状,探讨手卫生与医院感染的相关性,制定手卫生管理对策.方法 随机抽查临床科室部分医护人员手污染的现状、了解医护人员手携带细菌的种类及性质,分析手污染的原因.结果 医护人员在常规医疗活动中,手部细菌携带率为100.0%,洗手后细菌携带率为29.6%;携带的细菌主要是:大肠埃希菌、肺炎克雷伯菌、铜绿假单胞菌、产碱假单胞菌、变形菌属、产气肠杆菌、金黄色葡萄球菌、凝固酶阴性葡萄球菌和肠球菌属等.结论 医护人员手部污染是医院感染的重要危险因素,必须强化医护人员预防医院感染的理念,提高对洗手的认知性和依从性,优化手卫生措施,有效预防与控制经手传播的医院感染.%OBJECTIVE To investigate the status of hand hygiene and hand-washing compliance of medical staffs and approach the correlation between hand hygiene and nosocomial infections to institute the administration strategy of hand hygiene.METHODS The random inspection of hand hygiene was performed for random selected medical staffs in clinical departments.The species of carrying pathogens were determined, and the reasons for contamination were analyzed.RESULTS The carrying rate of pathogenic bacteria before hand-washing was 100.0% while that after hand-washing was 29.6%.The carrying pathogenic bacteria mostly comprised of Esche-richiacoli, Klebsiella pneumonia, Pseudomonas aeruginosa , P.alcaligenes, Proteus, Enterobacter aerogenes, Staphylococcus aureus, coagulase negative Staphylococcus, Enterococci and so on.CONCLUSION The hand contamination is an important risk factor for nosocomial infections.We should strengthen hospital infections awareness of medical staffs, enhance the recognition and compliance of hand-washing and optimize hand hygiene measures to prevent and effectively control the nosocomial infections communicated through hands.

  1. Hand hygiene and hand-washing compliance of medical staff:current status and administration strategies%医务人员手卫生与洗手依从性现状及管理对策

    Institute of Scientific and Technical Information of China (English)

    范文; 黄娥; 段六生; 雷鸿斌; 易光明

    2011-01-01

    目的 了解医务人员手卫生的现状,研究手卫生与医院感染的关系,从而制定手卫生管理对策.方法随机抽查8个临床科室部分医务人员手污染现状,研究医务人员手携带病原菌的种类及性质,分析其污染因素.结果医务人员工作过程中手细菌携带率为100.0%,洗手后细菌携带率为30.4%;携带的主要细菌为:大肠埃希菌、肺炎克雷伯菌、铜绿假单胞菌、产碱假单胞菌、变形菌属、金黄色葡萄球菌、凝固酶阴性葡萄球菌和肠球菌属等.结论医务人员手部污染是医院交叉感染的重要危险因素,必须强化医务人员医院感染理念教育,重视手卫生的监督管理,提高对洗手的认知性和依从性,才能有效预防与控制由手传播的医院内交叉感染.%OBJECTIVE To understand the status of hand hygiene of medical staff and investigate the relation between hand hygiene and nosocomial infections to institute the administration strategy of hand hygiene.METHODS The random inspection of hand hygiene was performed for parts of medical staff in 8 clinical departments. The species of carrying pathogens were investigated. The reasons for contamination were analyzed.RESULTS The carrying rate of pathogenic bacteria before hand-washing was 100. 0% while which after hand-washing was 30.4 %. The common pathogenic were Escherichia coli, Klebsiella pneumouia, Pseudomonas aeruginosa , Pseudomonas alcaligenes , Bacillus proteus, Staphylococcus aureus , Coagulase negative Staphylococcus and Enterococci, and so on. CONCLUSION The hand contamination is the important risk factor of hospital cross infection. The hospital infections idea of medical staff should be strengthened, the supervision of hand hygiene and the enhancement of the recognition and compliance of hand-washing should be attached importance to effectively prevent and control the hospital cross infection communicated through hands.

  2. RF Pulsed Heating

    Energy Technology Data Exchange (ETDEWEB)

    Pritzkau, David P.

    2002-01-03

    RF pulsed heating is a process by which a metal is heated from magnetic fields on its surface due to high-power pulsed RF. When the thermal stresses induced are larger than the elastic limit, microcracks and surface roughening will occur due to cyclic fatigue. Pulsed heating limits the maximum magnetic field on the surface and through it the maximum achievable accelerating gradient in a normal conducting accelerator structure. An experiment using circularly cylindrical cavities operating in the TE{sub 011} mode at a resonant frequency of 11.424 GHz is designed to study pulsed heating on OFE copper, a material commonly used in normal conducting accelerator structures. The high-power pulsed RF is supplied by an X-band klystron capable of outputting 50 MW, 1.5 {micro}s pulses. The test pieces of the cavity are designed to be removable to allow testing of different materials with different surface preparations. A diagnostic tool is developed to measure the temperature rise in the cavity utilizing the dynamic Q change of the resonant mode due to heating. The diagnostic consists of simultaneously exciting a TE{sub 012} mode to steady-state in the cavity at 18 GHz and measuring the change in reflected power as the cavity is heated from high-power pulsed RF. Two experimental runs were completed. One run was executed at a calculated temperature rise of 120 K for 56 x 10{sup 6} pulses. The second run was executed at a calculated temperature rise of 82 K for 86 x 10{sup 6} pulses. Scanning electron microscope pictures show extensive damage occurring in the region of maximum temperature rise on the surface of the test pieces.

  3. Efficient Pulsed Quadrupole

    CERN Document Server

    Petzenhauser, I.; Spiller, P.; Tenholt, C.

    2016-01-01

    In order to raise the focusing gradient in case of bunched beam lines, a pulsed quadrupole was designed. The transfer channels between synchrotrons as well as the final focusing for the target line are possible applications. The quadrupole is running in a pulsed mode, which means an immense saving of energy by avoiding standby operation. Still the high gradients demand high currents. Hence a circuit had to be developed which is able to recover a significant amount of the pulsing energy for following shots. The basic design of the electrical circuit of the quadrupole is introduced. Furthermore more energy efficient circuits are presented and the limits of adaptability are considered.

  4. Pulse joining cartridges

    Energy Technology Data Exchange (ETDEWEB)

    Golovashchenko, Sergey Fedorovich; Bonnen, John Joseph Francis

    2016-08-23

    A pulsed joining tool includes a tool body that defines a cavity that receives an inner tubular member and an outer tubular member and a pulse joining cartridge. The tubular members are nested together with the cartridge being disposed around the outer tubular member. The cartridge includes a conductor, such as a wire or foil, that extends around the outer tubular member and is insulated to separate a supply segment from a return segment. A source of stored electrical energy is discharged through the conductor to join the tubular members with an electromagnetic force pulse.

  5. DogPulse

    DEFF Research Database (Denmark)

    Skovgaard, Christoffer; Thomsen, Josephine Raun; Verdezoto, Nervo;

    2015-01-01

    This paper presents DogPulse, an ambient awareness system to support the coordination of dog walking among family members at home. DogPulse augments a dog collar and leash set to activate an ambient shape-changing lamp and visualize the last time the dog was taken for a walk. The lamp gradually...... changes its form and pulsates its lights in order to keep the family members aware of the dog walking activity. We report the iterative prototyping of DogPulse, its implementation and its preliminary evaluation. Based on our initial findings, we present the limitations and lessons learned as well...

  6. Veterans Health Administration

    Science.gov (United States)

    ... code here VA » Veterans Health Administration Veterans Health Administration Robotic Brace for Veterans of Spinal Cord Injury ... Read more » VA Medical Centers The Veterans Health Administration is home to the United States’ largest integrated ...

  7. Fully automated system for pulsed NMR measurements

    Energy Technology Data Exchange (ETDEWEB)

    Cantor, David Milton

    1977-01-01

    A system is described which places many of the complex, tedious operations for pulsed NMR experiments under computer control. It automatically optimizes the experiment parameters of pulse length and phase, and precision, accuracy, and measurement speed are improved. The hardware interface between the computer and the NMR instrument is described. Design features, justification of the choices made between alternative design strategies, and details of the implementation of design goals are presented. Software features common to all the available experiments are discussed. Optimization of pulse lengths and phases is performed via a sequential search technique called Uniplex. Measurements of the spin-lattice and spin-spin relaxation times and of diffusion constants are automatic. Options for expansion of the system are explored along with some of the limitations of the system.

  8. The administration of human services.

    Science.gov (United States)

    Hasenfeld, Y

    1985-05-01

    Human service programs have gone from a period of rapid growth in the 1960s and early 1970s to a period of retrenchment in the 1980s. The changing political and economic context has forced these programs to undergo major organizational transformations and to adopt different administrative strategies. These include degovernmentalization of social services, reliance on cutback management, and deprofessionalization of human-service workers. The article explores the implications of these developments on the delivery of services to the public.

  9. EPA Administrative Enforcement Dockets

    Data.gov (United States)

    U.S. Environmental Protection Agency — The EPA Administrative Enforcement Dockets database contains the electronic dockets for administrative penalty cases filed by EPA Regions and Headquarters. Visitors...

  10. Administrative Data Repository (ADR)

    Data.gov (United States)

    Department of Veterans Affairs — The Administrative Data Repository (ADR) was established to provide support for the administrative data elements relative to multiple categories of a person entity...

  11. Pulse measurement apparatus and method

    Science.gov (United States)

    Marciante, John R.; Donaldson, William R.; Roides, Richard G.

    2011-10-25

    An embodiment of the invention is directed to a pulse measuring system that measures a characteristic of an input pulse under test, particularly the pulse shape of a single-shot, nano-second duration, high shape-contrast optical or electrical pulse. An exemplary system includes a multi-stage, passive pulse replicator, wherein each successive stage introduces a fixed time delay to the input pulse under test, a repetitively-gated electronic sampling apparatus that acquires the pulse train including an entire waveform of each replica pulse, a processor that temporally aligns the replicated pulses, and an averager that temporally averages the replicated pulses to generate the pulse shape of the pulse under test. An embodiment of the invention is directed to a method for measuring an optical or an electrical pulse shape. The method includes the steps of passively replicating the pulse under test with a known time delay, temporally stacking the pulses, and temporally averaging the stacked pulses. An embodiment of the invention is directed to a method for increasing the dynamic range of a pulse measurement by a repetitively-gated electronic sampling device having a rated dynamic range capability, beyond the rated dynamic range of the sampling device; e.g., enhancing the dynamic range of an oscilloscope. The embodied technique can improve the SNR from about 300:1 to 1000:1. A dynamic range enhancement of four to seven bits may be achieved.

  12. Enacting Governance through Strategy

    DEFF Research Database (Denmark)

    Brandtner, Christof; Höllerer, Markus A.; Meyer, Renate E.

    2017-01-01

    along four core dimensions: the setting in space and time, the definition of the public, the framing of the res publica and legitimacy issues. Moreover, our comparative analysis of Sydney and Vienna gives evidence of differences in governance configurations enacted through strategy documents....... of strategy documents in city administration addresses these challenges. Our central claim is that strategy documents can be understood as a distinct discursive device through which local governments enact aspired governance configurations. We illustrate our argument empirically using two prominent examples...... that, while showing similar features and characteristics, are anchored in different administrative traditions and institutional frameworks: the city administrations of Sydney, Australia, and Vienna, Austria. The contribution of the paper is to show how strategy documents enact governance configurations...

  13. Pulse subtraction Doppler

    Science.gov (United States)

    Mahue, Veronique; Mari, Jean Martial; Eckersley, Robert J.; Caro, Colin G.; Tang, Meng-Xing

    2010-01-01

    Recent advances have demonstrated the feasibility of molecular imaging using targeted microbubbles and ultrasound. One technical challenge is to selectively detect attached bubbles from those freely flowing bubbles and surrounding tissue. Pulse Inversion Doppler is an imaging technique enabling the selective detection of both static and moving ultrasound contrast agents: linear scatterers generate a single band Doppler spectrum, while non-linear scatterers generate a double band spectrum, one being uniquely correlated with the presence of contrast agents and non-linear tissue signals. We demonstrate that similar spectrums, and thus the same discrimination, can be obtained through a Doppler implementation of Pulse Subtraction. This is achieved by reconstructing a virtual echo using the echo generated from a short pulse transmission. Moreover by subtracting from this virtual echo the one generated from a longer pulse transmission, it is possible to fully suppress the echo from linear scatterers, while for non-linear scatterers, a signal will remain, allowing classical agent detection. Simulations of a single moving microbubble and a moving linear scatterer subject to these pulses show that when the virtual echo and the long pulse echo are used to perform pulsed Doppler, the power Doppler spectrum allows separation of linear and non-linear moving scattering. Similar results are obtained on experimental data acquired on a flow containing either microbubble contrast agents or linear blood mimicking fluid. This new Doppler method constitutes an alternative to Pulse Inversion Doppler and preliminary results suggest that similar dual band spectrums could be obtained by the combination of any non-linear detection technique with Doppler demodulation.

  14. Pulsed spallation Neutron Sources

    Energy Technology Data Exchange (ETDEWEB)

    Carpenter, J.M. [Argonne National Lab., IL (United States)

    1994-12-31

    This paper reviews the early history of pulsed spallation neutron source development at Argonne and provides an overview of existing sources world wide. A number of proposals for machines more powerful than currently exist are under development, which are briefly described. The author reviews the status of the Intense Pulsed Neutron Source, its instrumentation, and its user program, and provides a few examples of applications in fundamental condensed matter physics, materials science and technology.

  15. Four pulse recoupling

    Science.gov (United States)

    Khaneja, Navin; Kumar, Ashutosh

    2016-11-01

    The paper describes a family of novel recoupling pulse sequences in magic angle spinning (MAS) solid state NMR, called four pulse recoupling. These pulse sequences can be employed for both homonuclear and heteronuclear recoupling experiments and are robust to dispersion in chemical shifts and rf-inhomogeneity. The homonuclear pulse sequence consists of a building block (π/2) 0 °(3π/2) ϕ°(π/2) 180 ° + ϕ°(3π/2) 180 ° where ϕ = π/n (ϕ° = 180°/n) , and n is number of blocks in a two rotor period. The heteronuclear recoupling pulse sequence consists of a building block (π/2) 0 °(3π/2) ϕ1 °(π/2) 180 ° +ϕ1 °(3π/2) 180 ° and (π/2) 0 °(3π/2) ϕ2 °(π/2) 180 ° +ϕ2 °(3π/2) 180 ° on channel I and S, where ϕ1 = 3π/2n, ϕ2 = π2/n and n is number of blocks in a two rotor period. The recoupling pulse sequences mix the y magnetization. We show that four pulse recoupling is more broadband compared to three pulse recoupling [1]. Experimental quantification of this method is shown for 13Cα-13CO, homonuclear recoupling in a sample of Glycine and 15N-13Cα, heteronuclear recoupling in Alanine. Application of this method is demonstrated on a sample of tripeptide N-formyl-[U-13C,15N]-Met-Leu-Phe-OH (MLF).

  16. 司法解释放弃定义具体行政行为的策略检讨%Review the Strategy of Giving up the Specific Administrative Act Definition of Judicial Interpretations

    Institute of Scientific and Technical Information of China (English)

    闫尔宝

    2012-01-01

    现行行政诉讼法建立了以具体行政行为为中心的行政诉讼制度体系,如何理解具体行政行为具有极为重要的理论意义与法律适用意义。在先后两个系统的司法解释中,最高人民法院采用了完全不同的解释策略,对具体行政行为先给出了明确界定,后又基于各种考虑而放弃。司法解释先后态度的不同,对我国的行政行为法理论和行政诉讼制度的理解与完善构成了一定影响。当前,我国行政诉讼法进入修改阶段,通过借鉴其他国家或地区的经验教训,重新认识和评估具体行政行为定义的价值,可以为发展我国的行政行为法理论、重新认识行政诉讼制度并更好地做好立法修订工作提供另外一种参照视角。%The administrative procedural law of China has established an administrative litigation system which makes the specific administrative act as the centre, how to understand this particular conception is of great significance not only to theory but also to the application of the law. In its two judicial interpretations of the law, the Supreme People' s Court has adopted a completely different interpretation of policy, at first, it gave out a clear definition to the specific administrative act, and then give it up for various reasons. The different attitudes of the judicial interpretation has certain influence on the theory of administrative law and administrative litigation. Currently, there is an movement of modification of administrative procedure law in China, through the lessons and experience of other countries or regions, recognition and evaluation the definition of the specific administrative act may provide another view of a reference to the development of China' s system of administrative act theory, rethinking administrative action and improving the work of legislative amendments

  17. 桥头堡建设背景下的云南公安出入境管理争取国家政策支持的思考%Thinking On Applying for National Policy Support of Exit and Entry Administration of Yunnan Public Security on the Background of Bridgehead Strategy

    Institute of Scientific and Technical Information of China (English)

    肖震宇

    2012-01-01

    "两强一堡"战略是统领云南社会经济发展的主体,云南公安出入境管理工作积极争取国家政策支持,为"桥头堡"建设提供良好环境。本文试从上述观点出发,结合实际工作,提出对策建议和政策支持。%The Strategy of Building Province of Green Economy and Ethnic Culture Strength and the Bridgehead Strategy are principles of social and economic development of Yunnan province. The exit and entry administration of Yunnan public security shall apply for national policy support actively, providing a favorable environment for implementing the Bridgehead strategy. This essay, based on the mentioned standpoint, combi- ning practice of this field, proposes measures, ,suggestion, and supporting policy.

  18. High voltage pulse generator

    Science.gov (United States)

    Fasching, George E.

    1977-03-08

    An improved high-voltage pulse generator has been provided which is especially useful in ultrasonic testing of rock core samples. An N number of capacitors are charged in parallel to V volts and at the proper instance are coupled in series to produce a high-voltage pulse of N times V volts. Rapid switching of the capacitors from the paralleled charging configuration to the series discharging configuration is accomplished by using silicon-controlled rectifiers which are chain self-triggered following the initial triggering of a first one of the rectifiers connected between the first and second of the plurality of charging capacitors. A timing and triggering circuit is provided to properly synchronize triggering pulses to the first SCR at a time when the charging voltage is not being applied to the parallel-connected charging capacitors. Alternate circuits are provided for controlling the application of the charging voltage from a charging circuit to be applied to the parallel capacitors which provides a selection of at least two different intervals in which the charging voltage is turned "off" to allow the SCR's connecting the capacitors in series to turn "off" before recharging begins. The high-voltage pulse-generating circuit including the N capacitors and corresponding SCR's which connect the capacitors in series when triggered "on" further includes diodes and series-connected inductors between the parallel-connected charging capacitors which allow sufficiently fast charging of the capacitors for a high pulse repetition rate and yet allow considerable control of the decay time of the high-voltage pulses from the pulse-generating circuit.

  19. Case of administrative dispute

    Directory of Open Access Journals (Sweden)

    Xhemazie Ibraimi

    2015-11-01

    Full Text Available The activity of administrative bodies includes big numbers of various acts and actions, through which the will of public administration is formed. The will of public administration bodies, expressed in administrative individual and normative acts, in administrative contracts and real acts, finds its reflection in the Constitution, laws and other provisions of legal character. All this activity is not inerrant and therefore, it is not uncontrollable. The supervision of executive activity is subject to political control of administrative acts through authorities designated for this purpose, as well as internal control and the judicial control. The institution of judicial control of administrative acts and actions appears as very important and widely treated in the legal doctrine. The protection of constitutional and legal rights of private persons is accomplished by subjecting administrative activity both to internal administrative control, as well as to the judicial control in accordance with legal provisions. The judicial control of administrative acts represents a constitutional guarantee for citizens to protect their rights through public and fair trial by an independent and impartial court. In this way, the Constitution empowers the common administrative court that invalidates an action or administrative act, but not all administrative acts may be subject to administrative dispute, with the exception of cases against which the administrative conflict cannot be carried out (negative enumeration.

  20. Analyzing the Relationship of Geographic Mobility and Institutional Prestige to Career Advancement of Women in Academic Medicine Pursuing Midcareer-, Senior-, or Executive-Level Administrative Positions: Implications for Career Advancement Strategies

    Science.gov (United States)

    McLean, Marsha Renee

    2010-01-01

    The purpose of this study was to explore the relationship of geographic mobility and institutional prestige to career advancement defined as administrative promotions of women seeking midcareer-, senior-, or executive-level positions at academic health centers (AHCs) and their medical schools or in non-AHC related medical schools in the United…

  1. Discharge pulse phenomenology

    Science.gov (United States)

    Frederickson, A. R.

    1985-01-01

    A model was developed which places radiation induced discharge pulse results into a unified conceptual framework. Only two phenomena are required to interpret all space and laboratory results: (1) radiation produces large electrostatic fields inside insulators via the trapping of a net space charge density; and (2) the electrostatic fields initiate discharge streamer plasmas similar to those investigated in high voltage electrical insulation materials; these streamer plasmas generate the pulsing phenomena. The apparent variability and diversity of results seen is an inherent feature of the plasma streamer mechanism acting in the electric fields which is created by irradiation of the dielectrics. The implications of the model are extensive and lead to constraints over what can be done about spacecraft pulsing.

  2. Pulsed ELDOR detected NMR

    Science.gov (United States)

    Schosseler, P.; Wacker, Th.; Schweiger, A.

    1994-07-01

    A pulsed EPR method for the determination of small hyperfine interactions in disordered systems is described. A selective preparation pulse of frequency ω mw(1) excites allowed and forbidden transitions, thereby burning spectral holes into the EPR line. The positions of the holes caused by the excitation of forbidden transitions correspond to the nuclear transition frequencies of the spin system. A selective detection pulse of frequency ω mw(2) creates an FID with integrated intensity proportional to the magnetization at frequency ω mw(2). The entire hole pattern is obtained by recording the integrated intensity of the FID while varying the frequency difference Δω mw=ω mw(1)-ω mw(2) step by step.

  3. Herophilus on pulse

    Directory of Open Access Journals (Sweden)

    Afonasin, Eugene

    2015-01-01

    Full Text Available The first detailed study of the pulse (sphygmology is associated in antiquity with Herophilus (the end of the 4th century BCE, an Alexandrian physician, renowned for his anatomical discoveries. The scholars also attribute to him a discovery of a portable and adjustable water-clock, used for measuring ‘natural’ and ‘unnatural’ pulse and, accordingly, temperature of the patient. In the article we translate the principal ancient evidences and comment upon them. We study both the practical aspects of ancient sphygmology and the theoretical speculations associated with it. Ancient theory of proportion and musical harmony allowed to build a classification of the pulses, but the medical experience did not fit well in the Procrustean bed of this rather simple theory.

  4. Pulsed Artificial Electrojet Generation

    Science.gov (United States)

    Papadopoulos, K.

    2008-12-01

    Traditional techniques for generating low frequency signals in the ULF/ELF range (.1-100 Hz) and rely on ground based Horizontal Electric Dipole (HED) antennas. It is, furthermore, well known that a Vertical Electric Dipole (VED) is by more than 50 dB more efficient than a HED with the same dipole current moment. However, the prohibitively long length of VED antennas in the ELF/ULF range coupled with voltage limitations due to corona discharge in the atmosphere make them totally impracticable. In this paper we discuss a novel concept, inspired by the physics of the equatorial electrojet, that allows for the conversion of a ground based HED to a VED in the E-region of the equatorial ionosphere with current moment comparable to the driving HED. The paper focuses in locations near the dip-equator, where the earth's magnetic is in predominantly in the horizontal direction. The horizontal electric field associated with a pulsed HED drives a large Hall current in the ionospheric E-region, resulting in a vertical current. It is shown that the pulsed vertical current in the altitude range 80-130 km, driven by a horizontal electric field of, approximately, .1 mV/m at 100 km altitude, is of the order of kA. This results in a pulsed VED larger than 106 A-m. Such a pulsed VED will drive ELF/ULF pulses with amplitude in excess of .1 nT at a lateral range larger than few hundred kilometers. This is by three orders of magnitude larger than the one expected by a HED with comparable current moment. The paper will conclude with the description of a sneak-through technique that allows for creating pulsed electric fields in the ionosphere much larger than expected from steady state oscillatory HED antennas.

  5. Two pulse recoupling

    Science.gov (United States)

    Khaneja, Navin; Kumar, Ashutosh

    2017-08-01

    The paper describes a family of novel recoupling pulse sequences in magic angle spinning (MAS) solid state NMR, called two pulse recoupling. These pulse sequences can be employed for both homonuclear and heteronuclear recoupling experiments and are robust to dispersion in chemical shifts and rf-inhomogeneity. The homonuclear pulse sequence consists of a building block (π)ϕ(π) - ϕ where ϕ =π/4n, and n is number of blocks in a rotor period. The recoupling block is made robust to rf-inhomogeneity by extending it to (π)ϕ(π) - ϕ(π) π + ϕ(π) π - ϕ . The heteronuclear recoupling pulse sequence consists of a building block (π)ϕ1(π)-ϕ1 and (π)ϕ2(π)-ϕ2 on channel I and S, where ϕ1 = 3π/8n, ϕ2 = π/8n and n is number of blocks in a rotor period. The recoupling block is made robust to rf-inhomogeneity by extending it to (π)ϕ1(π)-ϕ1(π) π +ϕ1(π) π -ϕ1 and (π)ϕ2(π)-ϕ2(π) π +ϕ2(π) π -ϕ2 on two channels respectively. The recoupling pulse sequences mix the z magnetization. Experimental quantification of this method is shown for 13Cα-13CO homonuclear recoupling in a sample of Glycine and 15N-13Cα heteronuclear recoupling in Alanine. Application of this method is demonstrated on a sample of tripeptide N-formyl-[U-13C,15N]-Met-Leu-Phe-OH (MLF). Compared to R-sequences (Levitt, 2002), these sequences are more robust to rf-inhomogeneity and give better sensitivity, as shown in Fig. 3.

  6. Pulse Doppler radar

    CERN Document Server

    Alabaster, Clive

    2012-01-01

    This book is a practitioner's guide to all aspects of pulse Doppler radar. It concentrates on airborne military radar systems since they are the most used, most complex, and most interesting of the pulse Doppler radars; however, ground-based and non-military systems are also included. It covers the fundamental science, signal processing, hardware issues, systems design and case studies of typical systems. It will be a useful resource for engineers of all types (hardware, software and systems), academics, post-graduate students, scientists in radar and radar electronic warfare sectors and milit

  7. Pulsed Electron Holography

    CERN Document Server

    Germann, Matthias; Escher, Conrad; Fink, Hans-Werner

    2013-01-01

    A technique of pulsed low-energy electron holography is introduced that allows for recording highly resolved holograms within reduced exposure times. Therefore, stacks of holograms are accumulated in a pulsed mode with individual acquisition times as short as 50 {\\mu}s. Subsequently, these holograms are aligned and finally superimposed. The resulting holographic record reveals previously latent high-order interference fringes and thereby pushing interference resolution into the sub-nanometer regime. In view of the non-damaging character of low-energy electrons, the method is of particular interest for structural analysis of fragile biomolecules.

  8. ADMINISTRATIVE CONTRACTS. DELIMITATIONS

    Directory of Open Access Journals (Sweden)

    Liana Teodora PASCARIU

    2016-12-01

    Full Text Available Article examines whether all contracts of public persons are administrative contracts; in other words, if the administration may conclude contracts that, according to their legal nature, are not administrative. If we start from the definition of administrative contracts as it appears in Law no. 554/2004, these include contracts by public authorities which concern the enhancement of public property execution of works of public interest, public services, public procurement and other administrative contracts provided by special laws and subject to the jurisdiction of the administrative courts.

  9. Behavioral Public Administration

    DEFF Research Database (Denmark)

    Grimmelikhuijsen, Stephan; Jilke, Sebastian; Olsen, Asmus Leth

    2017-01-01

    Behavioral public administration is the analysis of public administration from the micro-level perspective of individual behavior and attitudes by drawing on insights from psychology on the behavior of individuals and groups. The authors discuss how scholars in public administration currently draw...... theories. As such, behavioral public administration complements traditional public administration. Furthermore, it could be a two-way street for psychologists who want to test the external validity of their theories in a political-administrative setting. Finally, four principles are proposed to narrow...

  10. Enacting Governance through Strategy

    DEFF Research Database (Denmark)

    Brandtner, Christof; Höllerer, Markus A.; Meyer, Renate E.

    2017-01-01

    Over the past two decades, research has emphasised a shift from city government to urban governance. Such a shift brings about its very own challenges, namely governance gaps, uncertain configurations in governance and a limited capacity to act. In this paper, we argue that the concurrent rise...... of strategy documents in city administration addresses these challenges. Our central claim is that strategy documents can be understood as a distinct discursive device through which local governments enact aspired governance configurations. We illustrate our argument empirically using two prominent examples...... that, while showing similar features and characteristics, are anchored in different administrative traditions and institutional frameworks: the city administrations of Sydney, Australia, and Vienna, Austria. The contribution of the paper is to show how strategy documents enact governance configurations...

  11. 某地药品安全监管信息化建设现状分析及创新策略%Situation and Innovation Strategy of Construction of Drug Safety Administration Information in A City

    Institute of Scientific and Technical Information of China (English)

    罗莉; 陈晓隽; 陈勇

    2016-01-01

    Objective To strengthen and innovate the construction of drug safety administration information in a city. Methods To in-vestigate the construction situation of the drug safety administration in one food and drug administration,and to analyze the current situ-ation and deficiency of the drug safety administration system. Results and Conclusion The countermeasure and suggestion of the con-struction of the drug safety administration were put forward on the basis of big data:to establish the big data thinking,innovative drug regulatory mode;build big data centers,perfect the drug safety administration model divined by information,construct the 3 big basic da-ta bases of pharmaceutical information,pharmaceutical enterprise subject information,pharmaceutical enterprise behavior,and consolidate the basis of information interconnection and intercommunication.%目的:促进药品安全监管信息化建设的加强和创新。方法对某地食品药品监管部门药品安全监管信息化建设情况进行调研,对其药品安全监管信息系统的运行现状及存在的不足进行分析。结果与结论基于大数据思维提出了药品安全监管信息化建设的对策与建议,即建立“大数据思维”,创新药品安全监管模式;构建大数据中心,完善信息驱动下的药品安全监管模式;建设药品信息、医药企业主体信息、医药企业行为三大基础数据库,夯实信息互联互通基础。

  12. SNMR pulse sequence phase cycling

    Science.gov (United States)

    Walsh, David O; Grunewald, Elliot D

    2013-11-12

    Technologies applicable to SNMR pulse sequence phase cycling are disclosed, including SNMR acquisition apparatus and methods, SNMR processing apparatus and methods, and combinations thereof. SNMR acquisition may include transmitting two or more SNMR pulse sequences and applying a phase shift to a pulse in at least one of the pulse sequences, according to any of a variety cycling techniques. SNMR processing may include combining SNMR from a plurality of pulse sequences comprising pulses of different phases, so that desired signals are preserved and indesired signals are canceled.

  13. Pulse distortion in single-mode fibers. 3: Chirped pulses.

    Science.gov (United States)

    Marcuse, D

    1981-10-15

    The theory of pulse distortion in single-mode fibers is extended to include laser sources that suffer a linear wavelength sweep (chirp) during the duration of the pulse. The transmitted pulse is expressed as a Fourier integral whose spectral function is given by an analytical expression in closed form. The rms width of the transmitted pulse is also expressed in closed form. Numerical examples illustrate the influence of the chirp on the shape and rms width of the pulse. A somewhat paradoxical situation exists. A given input pulse can be made arbitrarily short by a sufficiently large amount of chirping, and, after a given fiber length, this chirped pulse returns to its original width. But at this particular distance an unchirped pulse would be only [equiation] times longer. Thus chirping can improve the rate of data transmission by only 40%.

  14. Solid-state pulse forming module with adjustable pulse duration

    Science.gov (United States)

    Wang, Langning; Liu, Jinliang; Qiu, Yongfeng; Chu, Xu; Zhang, Qingmeng

    2017-03-01

    A new solid-state pulse forming module is described in this paper. The pulse forming module is fabricated on a glass ceramic substrate, with the dimension of 250 mm × 95 mm × 4 mm. By changing the copper strips used in the pulse forming modules, the pulse duration of the obtained pulsed can range from 80 ns to 140 ns. Both the simulation and tests show that the pulse forming module has a good pulse forming ability. Under a high voltage in microsecond's time, the new pulse forming modules can hold off a voltage up to 25 kV higher than that of the previous study. In addition, future optimization for the field enhancement near the thin electrode edge has been proposed and simulated.

  15. Development and Integration of a Pulsed 2-micron Direct Detection Integrated Path Differential Absorption (IPDA) Lidar for CO2 Column Measurement from Airborne platform Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Develop, integrate and demonstrate a 2-micron pulsed Integrated Path Differential Absorption Lidar (IPDA) instrument CO2 Column Measurement from Airborne platform...

  16. Transportation Security Administration

    Science.gov (United States)

    ... content Official website of the Department of Homeland Security Transportation Security Administration A - Z Index What Can I Bring? ... form Search the Site Main menu Administrator Travel Security Screening Special Procedures TSA Pre✓® Passenger Support Travel ...

  17. Administration for Community Living

    Science.gov (United States)

    ... Public Input Working Together, in Our Communities The Administration for Community Living was created around the fundamental ... Players U.S. Department of Health and Human Services, Administration for Community Living

  18. Administration on Aging

    Science.gov (United States)

    ... Federal Initiatives Career Opportunities Contact Us Administration on Aging (AoA) The Administration on Aging (AOA) is the ... themselves. Back to top Older Americans Act and Aging Network To meet the diverse needs of the ...

  19. SFOL Pulse: A High Accuracy DME Pulse for Alternative Aircraft Position and Navigation

    Directory of Open Access Journals (Sweden)

    Euiho Kim

    2017-09-01

    Full Text Available In the Federal Aviation Administration’s (FAA performance based navigation strategy announced in 2016, the FAA stated that it would retain and expand the Distance Measuring Equipment (DME infrastructure to ensure resilient aircraft navigation capability during the event of a Global Navigation Satellite System (GNSS outage. However, the main drawback of the DME as a GNSS back up system is that it requires a significant expansion of the current DME ground infrastructure due to its poor distance measuring accuracy over 100 m. The paper introduces a method to improve DME distance measuring accuracy by using a new DME pulse shape. The proposed pulse shape was developed by using Genetic Algorithms and is less susceptible to multipath effects so that the ranging error reduces by 36.0–77.3% when compared to the Gaussian and Smoothed Concave Polygon DME pulses, depending on noise environment.

  20. Analysis on X ( Low) Efficiency of Administrative Staff in Colleges and the Coping Strategies%高校行政管理人员X(低)效率分析及应对策略

    Institute of Scientific and Technical Information of China (English)

    涂双滨

    2015-01-01

    多层次委托代理关系、人的惰性特征和选择理性是导致高校行政管理人员X(低)效率的三种主要原因.将X(低)效率理论引入高校行政管理领域,提出高校行政管理人员X(低)效率的科学内涵,分析当前高校行政管理人员X(低)效率的具体表现和产生原因,从规范委托代理关系、加强制度建设和运用推拉理论等三个方面提出具体的对策建议.%Multi-level agency relationship, inertia characteristics and rational choice of the human are the three main reasons that lead to X ( low) efficiency of administrative staff in universities.Introducing X ( low) efficiency theory into the field of university administra-tion, this paper proposes the scientific connotation of X ( low) efficiency of university administrative staff, analyzes the specific per-formance and causes and gives specific countermeasures from the three aspects of specifying agency relationship, strengthening system construction and applying push-pull theory.

  1. Ultrafast optomechanical pulse picking

    Science.gov (United States)

    Lilienfein, Nikolai; Holzberger, Simon; Pupeza, Ioachim

    2017-01-01

    State-of-the-art optical switches for coupling pulses into and/or out of resonators are based on either the electro-optic or the acousto-optic effect in transmissive elements. In high-power applications, the damage threshold and other nonlinear and thermal effects in these elements impede further improvements in pulse energy, duration, and average power. We propose a new optomechanical switching concept which is based solely on reflective elements and is suitable for switching times down to the ten-nanosecond range. To this end, an isolated section of a beam path is moved in a system comprising mirrors rotating at a high angular velocity and stationary imaging mirrors, without affecting the propagation of the beam thereafter. We discuss three variants of the concept and exemplify practical parameters for its application in regenerative amplifiers and stack-and-dump enhancement cavities. We find that optomechanical pulse picking has the potential to achieve switching rates of up to a few tens of kilohertz while supporting pulse energies of up to several joules.

  2. Pulsed electric fields

    Science.gov (United States)

    The concept of pulsed electric fields (PEF) was first proposed in 1967 to change the behavior or microorganisms. The electric field phenomenon was identified as membrane rupture theory in the 1980s. Increasing the membrane permeability led to the application of PEF assisted extraction of cellular co...

  3. Pulsed inductive HF laser

    Energy Technology Data Exchange (ETDEWEB)

    Razhev, A M; Kargapol' tsev, E S [Institute of Laser Physics, Siberian Branch, Russian Academy of Sciences, Novosibirsk (Russian Federation); Churkin, D S; Demchuk, S V [Novosibirsk State University, Novosibirsk (Russian Federation)

    2016-03-31

    We report the results of experimentally investigated dependences of temporal, spectral and spatial characteristics of an inductive HF-laser generation on the pump conditions. Gas mixtures H{sub 2} – F{sub 2}(NF{sub 3} or SF6{sub 6}) and He(Ne) – H{sub 2} – F{sub 2}(NF{sub 3} or SF{sub 6}) were used as active media. The FWHM pulse duration reached 0.42 μs. This value corresponded to a pulsed power of 45 kW. For the first time, the emission spectrum of an inductive HF laser was investigated, which consisted of seven groups of bands with centres around the wavelengths of 2732, 2736, 2739, 2835, 2837, 2893 and 2913 nm. The cross section profile of the laser beam was a ring with a diameter of about 20 mm and width of about 5 mm. Parameters of laser operation in the repetitively pulsed regime were sufficiently stable. The amplitude instability of light pulses was no greater than 5% – 6%. (lasers)

  4. Downhole pulse tube refrigerators

    Energy Technology Data Exchange (ETDEWEB)

    Swift, G.; Gardner, D. [Los Alamos National Lab., NM (United States). Condensed Matter and Thermal Physics Group

    1997-12-01

    This report summarizes a preliminary design study to explore the plausibility of using pulse tube refrigeration to cool instruments in a hot down-hole environment. The original motivation was to maintain Dave Reagor`s high-temperature superconducting electronics at 75 K, but the study has evolved to include three target design criteria: cooling at 30 C in a 300 C environment, cooling at 75 K in a 50 C environment, cooling at both 75 K and 30 C in a 250 C environment. These specific temperatures were chosen arbitrarily, as representative of what is possible. The primary goals are low cost, reliability, and small package diameter. Pulse-tube refrigeration is a rapidly growing sub-field of cryogenic refrigeration. The pulse tube refrigerator has recently become the simplest, cheapest, most rugged and reliable low-power cryocooler. The authors expect this technology will be applicable downhole because of the ratio of hot to cold temperatures (in absolute units, such as Kelvin) of interest in deep drilling is comparable to the ratios routinely achieved with cryogenic pulse-tube refrigerators.

  5. Cloudera administration handbook

    CERN Document Server

    Menon, Rohit

    2014-01-01

    An easy-to-follow Apache Hadoop administrator's guide filled with practical screenshots and explanations for each step and configuration. This book is great for administrators interested in setting up and managing a large Hadoop cluster. If you are an administrator, or want to be an administrator, and you are ready to build and maintain a production-level cluster running CDH5, then this book is for you.

  6. Refinement for Administrative Policies

    OpenAIRE

    Dekker, MAC; Etalle, S Sandro

    2007-01-01

    Flexibility of management is an important requisite for access control systems as it allows users to adapt the access control system in accordance with practical requirements. This paper builds on earlier work where we defined administrative policies for a general class of RBAC models. We present a formal definition of administrative refinnement and we show that there is an ordering for administrative privileges which yields administrative refinements of policies. We argue (by giving an examp...

  7. ADMINISTRATIVE JUSTICE IN POLAND

    Directory of Open Access Journals (Sweden)

    J. Turłukowski

    2016-01-01

    Full Text Available This article begins with an analysis of the development of administrative justice in Poland over the last centuries. In particular, the author examines administrative jurisdiction before 1918, when Poland regained its independence, the period of the Duchy of Warsaw, the Kingdom of Poland, and the practice on Polish territory under Austrian and Prussian control. The author then moves to modern law by presenting the judicial system in Poland in general, especially the differences between the separate systems of general courts and administrative courts, and analyses the jurisdiction of voivodship (regional administrative courts, and the basic principles of judicial and administrative proceedings. The focus of study is mainly devoted to judicial and administrative procedure, rather than an administrative process of citizens before administrative authorities regulated in a separate Code of Administrative Procedure. The article describes the role of the judge (pointing out the differences between the active role of first instance judges and the limited capabilities of the judges of the appeal and the powers of the Supreme Court, in particular its power to adopt resolutions, which has agreat importance for the unification of the jurisprudence. A brief analysis is given to class actions, which in the Polish legal system are inadmissible in court and administrative proceedings. The articles provides a statistical cross-section illustrating the role of administrative jurisdiction. The author concludes with observations pointing up the progress of administrative jurisdiction in Poland, not only in the legal sense, but also in the cultural sense.

  8. HIGH ENERGY REPLACEMENT FOR TEFLON PROPELLANT IN PULSED PLASMA THRUSTERS Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This program will utilize a well-characterized Pulsed Plasma Thruster (PPT) to test experimental high-energy extinguishable solid propellants (HE), instead of...

  9. Pulsed, Single-Frequency, 2-um Seed Source for Coherent LIDAR Applications Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The primary objective of the proposed Phase I effort is to develop and demonstrate a low-average power, pulsed, single-frequency, 2-um Ho-laser source for...

  10. A 2-Micron Pulsed Laser Transmitter for Direct Detection Column CO2 Measurement from Space Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Develop a compact, efficient 2µm pulsed laser for a lidar instrument to make accurate, high-resolution atmospheric CO2 column measurements in support of the...

  11. Micro Pulsed Inductive Thruster with Solid Fuel Option (uPIT_SF) Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The Micro Pulsed Inductive Thruster with Solid Fuel Option (5PIT_SF) is a high-precision impulse bit electromagnetic plasma micro-thruster. The 5PIT prototype is a...

  12. A Green, Safe, Dual-pulse Solid Motor for CubeSat Orbit Changing Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Small satellites such as CubeSats are in need of responsive propulsion, but are limited due to their size. Though single pulse, AP/HTPB fueled solid rocket motors...

  13. Intrauterine Methylene Blue Injection Influences the Accuracy of Pulse Oximetry Readings

    Directory of Open Access Journals (Sweden)

    Fuh-Cheng Yeh

    2005-12-01

    Conclusions: Intraoperative administration of methylene blue may induce false low readings on pulse oximetry. The patient was not hypoxemic. If there is any doubt, arterial blood gas analysis should be done to ensure that the patient is well oxygenated.

  14. High Sensitivity Pulsed Laser Vibrometer for Aircraft Interior Noise Monitoring Project

    Data.gov (United States)

    National Aeronautics and Space Administration — We propose an innovative pulsed laser vibrometer technology for the monitoring of interior noise inside an aircraft. The optical speckle-tolerant nature of the...

  15. A Waveguide Based, High Power Pockels Cell Modulator for Sub-Nanosecond Pulse Slicing Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The Goal of this STTR is to develop a high speed, high power, waveguide based modulator (phase and amplitude) and investigate its use as a pulse slicer. The key...

  16. Sequentially pulsed traveling wave accelerator

    Science.gov (United States)

    Caporaso, George J.; Nelson, Scott D.; Poole, Brian R.

    2009-08-18

    A sequentially pulsed traveling wave compact accelerator having two or more pulse forming lines each with a switch for producing a short acceleration pulse along a short length of a beam tube, and a trigger mechanism for sequentially triggering the switches so that a traveling axial electric field is produced along the beam tube in synchronism with an axially traversing pulsed beam of charged particles to serially impart energy to the particle beam.

  17. Bacterial inactivation using pulsed light

    OpenAIRE

    Elmnasser, Noura; Ritz, Magali; Leroi, Francoise; Orange, Nicole; Bakhrouf, Amina; Federighi, Michel

    2007-01-01

    Pulsed light is a new method intended for the decontamination of food surfaces using short, high frequency pulses of an intense broad spectrum. The effects of broad spectrum pulsed light on the survival of Listeria monocytogenes Scott A, Listeria monocytogenes CNL, Pseudomonas fluorescens MF37 and Photobacterium phosphoreum SF680 populations on agar and in a liquid medium were investigated during this study. The sterilisation system generated 1.5 J cm(-2) per pulse with eight lamps for 300 mu...

  18. A THERMAL PULSE SHAPER MECHANISM.

    Science.gov (United States)

    A shaped pulse of intense thermal radiation, corresponding to the pulses from nuclear weapons, is obtained by the output of a QM carbon arc. A flywheel driven by a DC motor actuated a venetian blind shutter placed between a mirror and the target to control the flux. The combination produced reasonably good simulation and reproduction of the generalized field pulse.

  19. Research on Strategies of Implementation of Strategic Marketing of Hohhot Railway Administration%呼和浩特铁路局战略营销实施的对策研究

    Institute of Scientific and Technical Information of China (English)

    侯立新

    2012-01-01

    Management system and operational mechanism of Hohhot Railway Administration can not meet the requirements of market economy in the case of fierce market competition of transport service, which becomes increasingly obvious. Only basing on strategic perspective, using theory and ideas of strategic marketing to analyze huge market which faces, and forms own advantageous fields and characteristics combining with conditions of their own resources and cultivating core competitiveness constantly, can Hohhot Railway Administration seek survival and development in fierce market competition.%呼和浩特铁路局的管理体制和经营机制在运输业市场竞争日益激烈的情况下不能适应市场经济发展要求日趋明显,呼和浩特铁路局只有站在战略的高度,运用战略营销的理论与思想,分析所面临的巨大市场,结合自身资源条件并不断培育核心竞争力以形成自己的优势领域和特色,才能在激烈的市场竞争中谋求生存与发展.

  20. Noisy homoclinic pulse dynamics

    Science.gov (United States)

    Eaves, T. S.; Balmforth, Neil J.

    2016-04-01

    The effect of stochastic perturbations on nearly homoclinic pulse trains is considered for three model systems: a Duffing oscillator, the Lorenz-like Shimizu-Morioka model, and a co-dimension-three normal form. Using the Duffing model as an example, it is demonstrated that the main effect of noise does not originate from the neighbourhood of the fixed point, as is commonly assumed, but due to the perturbation of the trajectory outside that region. Singular perturbation theory is used to quantify this noise effect and is applied to construct maps of pulse spacing for the Shimizu-Morioka and normal form models. The dynamics of these stochastic maps is then explored to examine how noise influences the sequence of bifurcations that take place adjacent to homoclinic connections in Lorenz-like and Shilnikov-type flows.

  1. Computationally intelligent pulsed photoacoustics

    Science.gov (United States)

    Lukić, Mladena; Ćojbašić, Žarko; Rabasović, Mihailo D.; Markushev, Dragan D.

    2014-12-01

    In this paper, the application of computational intelligence in pulsed photoacoustics is discussed. Feedforward multilayer perception networks are applied for real-time simultaneous determination of the laser beam spatial profile and vibrational-to-translational relaxation time of the polyatomic molecules in gases. Networks are trained and tested with theoretical data adjusted for a given experimental set-up. Genetic optimization has been used for calculation of the same parameters, fitting the photoacoustic signals with a different number of generations. Observed benefits from the application of computational intelligence in pulsed photoacoustics and advantages over previously developed methods are discussed, such as real-time operation, high precision and the possibility of finding solutions in a wide range of parameters, similar to in experimental conditions. In addition, the applicability for practical uses, such as the real-time in situ measurements of atmospheric pollutants, along with possible further developments of obtained results, is argued.

  2. Micro pulse laser radar

    Science.gov (United States)

    Spinhirne, James D. (Inventor)

    1993-01-01

    An eye safe, compact, solid state lidar for profiling atmospheric cloud and aerosol scattering is disclosed. The transmitter of the micro pulse lidar is a diode pumped micro-J pulse energy, high repetition rate Nd:YLF laser. Eye safety is obtained through beam expansion. The receiver employs a photon counting solid state Geiger mode avalanche photodiode detector. Data acquisition is by a single card multichannel scaler. Daytime background induced quantum noise is controlled by a narrow receiver field-of-view and a narrow bandwidth temperature controlled interference filter. Dynamic range of the signal is limited to optical geometric signal compression. Signal simulations and initial atmospheric measurements indicate that micropulse lider systems are capable of detecting and profiling all significant cloud and aerosol scattering through the troposphere and into the stratosphere. The intended applications are scientific studies and environmental monitoring which require full time, unattended measurements of the cloud and aerosol height structure.

  3. Magnetic Pulse Welding Technology

    Directory of Open Access Journals (Sweden)

    Ahmad K. Jassim

    2011-12-01

    Full Text Available In this paper, the benefits of using Magnetic Pulse machine which is belong to Non-conventional machine instead of conventional machine. Magnetic Pulse Technology is used for joining dissimilar metals, and for forming and cutting metals. It is a non contact technique. Magnetic field is used to generate impact magnetic pressure for welding and forming the work piece by converted the electrical energy to mechanical energy. It is enable us to design previously not possible by welding dissimilar materials and allowing to welds light and stronger materials together. It can be used to weld metallic with non metallic materials to created mechanical lock on ceramics, polymers, rubbers and composites. It is green process; there is no heat, no radiation, no gas, no smoke and sparks, therefore the emissions are negligible.

  4. Measurement of pulse lengthening with pulse energy increase in picosecond Nd:YAG laser pulses

    Energy Technology Data Exchange (ETDEWEB)

    Cutolo, A.; Zeni, L.; Berardi, V.; Bruzzese, R.; Solimeno, S.; Spinelli, N.

    1989-03-15

    Taking advantage of a new technique, we have monitored the relative variations of time duration and mode size as a function of the pulse energy for 30-ps-long Nd:YAG laser pulses. In particular, by carrying out a statistical analysis, we have observed that the pulse time duration is an increasing function of the pulse energy, according to the theoretical modeling of passively mode-locked lasers. The measurements can be easily extended to the femtosecond regime.

  5. Twitter's visual pulse

    OpenAIRE

    Hare, Jonathon; Samangooei, Sina; Dupplaw, David; Lewis, Paul H.

    2013-01-01

    Millions of images are tweeted every day, yet very little research has looked at the non-textual aspect of social media communication. In this work we have developed a system to analyse streams of image data. In particular we explore trends in similar, related, evolving or even duplicated visual artefacts in the mass of tweeted image data — in short, we explore the visual pulse of Twitter.

  6. Pulse Portraiture: Pulsar timing

    Science.gov (United States)

    Pennucci, Timothy T.; Demorest, Paul B.; Ransom, Scott M.

    2016-06-01

    Pulse Portraiture is a wideband pulsar timing code written in python. It uses an extension of the FFTFIT algorithm (Taylor 1992) to simultaneously measure a phase (TOA) and dispersion measure (DM). The code includes a Gaussian-component-based portrait modeling routine. The code uses the python interface to the pulsar data analysis package PSRCHIVE (ascl:1105.014) and also requires the non-linear least-squares minimization package lmfit (ascl:1606.014).

  7. STUCTURE OF PULSED BED

    Directory of Open Access Journals (Sweden)

    I. A. Bokun

    2014-01-01

    Full Text Available The structure of pulsed layer is proposed which can be suggested as a state of particulates that is blown by intermittent gas flow with speed which has the force to start material moving. Layer during one cycle is in a suspension, falling down and immobile state resulting in changes of particles arrangement as well as ways of gas flowing through layer. Moreover, it allows carrying out effective interphase heat exchange even adamant real granulation.The process of formation of impact flows is considered aw well as their influence on formation of air bubbles in pulsed layer. At startup of air blast the balance between the force of hydro-dynamic resistance is broken, on one side, and forces of gravity, particles inertia and their links with walls on the other side. The layer is transferred in the state of pulsed pseudo-fluidization, and presents gas-disperse mixture, inside of which impulse of pressure increasing is spreading to all sides as pressure waves (compression. These waves are the sources of impact flows’ formation, the force of which is two times more than during the stationary flow.The waves of pressure are divided into weak and strong ones depending on movement velocity within gas-disperse system. Weak waves are moving with a sound speed and strong ones in active phase of pulsed layer are moving over the speed of sound limit within gas-disperse system. The peculiarity of strong wave is that parameters of system (pressure, density and others are changing in discrete steps.The article describes the regime of layer’s falling down in the passive stage of cycle, which begins after finishing of gas impulse action. And suspension layer of moving up granular material is transferred in the state of falling resulting in change of the layer structure.

  8. Downhole pulse radar

    Science.gov (United States)

    Chang, Hsi-Tien

    1987-09-28

    A borehole logging tool generates a fast rise-time, short duration, high peak-power radar pulse having broad energy distribution between 30 MHz and 300 MHz through a directional transmitting and receiving antennas having barium titanate in the electromagnetically active region to reduce the wavelength to within an order of magnitude of the diameter of the antenna. Radar returns from geological discontinuities are sampled for transmission uphole. 7 figs.

  9. Ptychographic ultrafast pulse reconstruction

    CERN Document Server

    Spangenberg, D; Brügmann, M H; Feurer, T

    2014-01-01

    We demonstrate a new ultrafast pulse reconstruction modality which is somewhat reminiscent of frequency resolved optical gating but uses a modified setup and a conceptually different reconstruction algorithm that is derived from ptychography. Even though it is a second order correlation scheme it shows no time ambiguity. Moreover, the number of spectra to record is considerably smaller than in most other related schemes which, together with a robust algorithm, leads to extremely fast convergence of the reconstruction.

  10. PULSE Pilot Certification Results

    Directory of Open Access Journals (Sweden)

    Pamela Pape-Lindstrom

    2015-08-01

    Full Text Available The pilot certification process is an ambitious, nationwide endeavor designed to motivate important changes in life sciences education that are in line with the recommendations of the 2011 Vision and Change Report: A Call to Action (American Association for the Advancement of Science [AAAS], 2011.  It is the goal of the certification process to acknowledge departments that have progressed towards full implementation of the tenets of Vision and Change and to motivate departments that have not begun to adopt the recommendations to consider doing so.  More than 70 life science departments applied to be part of the pilot certification process, funded by a National Science Foundation grant, and eight were selected based on initial evidence of transformed and innovative educational practices.  The programs chosen represent a wide variety of schools, including two-year colleges, liberal-arts institutions, regional comprehensive colleges, research universities and minority serving institutions.  Outcomes from this pilot were released June 1, 2015 (www.pulsecommunity.org, with all eight programs being recognized as having progressed along a continuum of change.  Five levels of achievement were defined as PULSE Pilot Progression Levels.  Of the eight departments in the pilot, one achieved “PULSE Progression Level III: Accomplished”.  Six departments achieved “PULSE Progression Level II: Developing” and one pilot department achieved “PULSE Progression Level I: Beginning”.  All of the schools have made significant movement towards the recommendations of Vision and Change relative to a traditional life sciences curriculum.  Overall, the response from the eight pilot schools has been positive. 

  11. Petawatt pulsed-power accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Stygar, William A. (Albuquerque, NM); Cuneo, Michael E. (Albuquerque, NM); Headley, Daniel I. (Albuquerque, NM); Ives, Harry C. (Albuquerque, NM); Ives, legal representative; Berry Cottrell (Albuquerque, NM); Leeper, Ramon J. (Albuquerque, NM); Mazarakis, Michael G. (Albuquerque, NM); Olson, Craig L. (Albuquerque, NM); Porter, John L. (Sandia Park, NM); Wagoner; Tim C. (Albuquerque, NM)

    2010-03-16

    A petawatt pulsed-power accelerator can be driven by various types of electrical-pulse generators, including conventional Marx generators and linear-transformer drivers. The pulsed-power accelerator can be configured to drive an electrical load from one- or two-sides. Various types of loads can be driven; for example, the accelerator can be used to drive a high-current z-pinch load. When driven by slow-pulse generators (e.g., conventional Marx generators), the accelerator comprises an oil section comprising at least one pulse-generator level having a plurality of pulse generators; a water section comprising a pulse-forming circuit for each pulse generator and a level of monolithic triplate radial-transmission-line impedance transformers, that have variable impedance profiles, for each pulse-generator level; and a vacuum section comprising triplate magnetically insulated transmission lines that feed an electrical load. When driven by LTD generators or other fast-pulse generators, the need for the pulse-forming circuits in the water section can be eliminated.

  12. 21 CFR 7.42 - Recall strategy.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Recall strategy. 7.42 Section 7.42 Food and Drugs....42 Recall strategy. (a) General. (1) A recall strategy that takes into account the following factors... Administration will review the adequacy of a proposed recall strategy developed by a recalling firm and...

  13. Judge Financial, Administrative Judge

    OpenAIRE

    Kurek, Aline

    2010-01-01

    As a specialised administrative judge, the financial judge, understood in the sense of the Auditors Court, of the regional Auditors Courts and of the Court of budgetary and financial discipline, has a ratione materiae jurisdiction. It is the judge's duty to ensure compliance with budgetary and national accounting rules. The perspective tending to view the financial judge as a administrative judge, that is to say as an ordinary administrative judge, may consequently give rise to certain object...

  14. Personality Traits and Administrators

    OpenAIRE

    Anitha V

    2008-01-01

    Administration is the art of getting tasks done by utilizing the resources and coordinating the people. Administrators give trigger to the administration by coordinating, and directing all parts of an organization by managing the tangible and intangible resources of the organization. The qualities of leadership are therefore a critical determinant of organizational success. The theories of leadership (Trait to Transformational leadership theory) have strived to look into the aspects that make...

  15. REVOCATION OF ADMINISTRATIVE ACT

    Directory of Open Access Journals (Sweden)

    MARTA CLAUDIA CLIZA

    2012-05-01

    Full Text Available Because the revocation is totally specific for administrative law principles, I chose to talk about in this study and its impact on the cancellation of administrative acts. Revocation will be explored, in terms of the authorities which it may provide but also of the effects caused.It also would examine if revocation has a legal basis, as well as real cases to provide the impact of this principle in administrative law.

  16. Humanism, Administration and Education

    DEFF Research Database (Denmark)

    Plum, Maja

    2012-01-01

    Abstract Through the example of a Danish reform of educational plans in early childhood education, this paper analyses the emergence of a new pedagogical desire related to administrative educational reforms promoting accountability, visibility and documentation. Two arguments are made: first...... are not restricted to the administrative practices, but are part of education and its humanistic legacy as well. As such, the administrative demand of documentation becomes possible and recognisable through its reproductive elements. Elements that are constituted in a transformative conjunction in which...

  17. Pulse Distributing Manifold; Pulse Distributing Manifold

    Energy Technology Data Exchange (ETDEWEB)

    Schutting, Eberhard [Technische Univ. Graz (Austria); Sams, Theodor [AVL List GmbH, Graz (Austria); Glensvig, Michael [Forschungsgesellschaft mbH, Graz (AT). Kompetenzzentrum ' ' Das virtuelle Fahrzeug' ' (VIF)

    2011-07-01

    The Pulse Distributing Manifold is a new charge exchange method for turbocharged diesel engines with exhaust gas recirculation (EGR). The method is characterized in that the EGR mass flow is not diverted from the exhaust gas mass flow continuously, but over time broken into sub-streams. The temporal interruption is achieved by two phase-shifted outlet valves which are connected via separate manifolds only with the turbocharger or only with the EGR path. The time points of valve opening are chosen such that the turbocharger and the aftertreatment process of exhaust gas is perfused by high-energy exhaust gas of the blowdown phase while cooler and less energy-rich exhaust gas of the exhaust period is used for the exhaust gas recirculation. This increases the enthalpy for the turbocharger and the temperature for the exhaust gas treatment, while the cooling efficiency at the EGR cooler is reduced. The elimination of the continuous EGR valve has a positive effect on pumping losses. The principle functioning and the potential of this system could be demonstrated by means of a concept study using one-dimensional simulations. Without disadvantages in fuel consumption for the considered commercial vehicle engine, a reduction the EGR cooler performance by 15 % and an increase in exhaust temperature of 35 K could be achieved. The presented charge exchange method was developed, evaluated and patented within the scope of the research program 'K2-mobility' of the project partners AVL (Mainz, Federal Republic of Germany) and University of Technology Graz (Austria). The research project 'K2-Mobility' is supported by the competence center 'The virtual vehicle' Forschungsgesellschaft mbH (Graz, Austria).

  18. 跨行政区域煤炭资源整合策略研究%Research on the Strategies for the“Trans-Administrative Region”Integration of Coal Resource

    Institute of Scientific and Technical Information of China (English)

    裴慧杰

    2013-01-01

    The“trans-administrative region”integration of coal resource follows the objective rules such as differences of natural conditions between provinces depending on coal industry as a supportive force, unbalanced development of the industry, and consistent appeal for subjects’ interest among regions depending on coal industry. Based on the demand of market construction for reasonable development and optimization of coal resource, we should break administrative interference among the regions and establish virtual management alliance for comprehensive development of coal resource in provinces which are connected and blessed with coal resource. As economical subjects, we should realize our advantage of highly efficient integration of coal resource, so as to promote market distribution of coal resource, and realize sustainable development of economy depending on coal resource.%煤炭资源的“跨行政区域”整合,遵循了煤炭支柱型产业省区间的自然资源禀赋差异、行业发展失衡和煤炭经济区域主体利益诉求一致的客观规律。立足煤炭资源合理开发和优化利用的市场化建设需求,需打破跨越煤炭经济行政主体的体制干预壁垒,在煤炭资源储存联片省区间构建综合开发虚拟管理联盟,高效集成煤炭资源经济主体优势,推动煤炭资源的市场化配置和煤炭经济的可持续性发展。

  19. High-speed pulse-shape generator, pulse multiplexer

    Science.gov (United States)

    Burkhart, Scott C.

    2002-01-01

    The invention combines arbitrary amplitude high-speed pulses for precision pulse shaping for the National Ignition Facility (NIF). The circuitry combines arbitrary height pulses which are generated by replicating scaled versions of a trigger pulse and summing them delayed in time on a pulse line. The combined electrical pulses are connected to an electro-optic modulator which modulates a laser beam. The circuit can also be adapted to combine multiple channels of high speed data into a single train of electrical pulses which generates the optical pulses for very high speed optical communication. The invention has application in laser pulse shaping for inertial confinement fusion, in optical data links for computers, telecommunications, and in laser pulse shaping for atomic excitation studies. The invention can be used to effect at least a 10.times. increase in all fiber communication lines. It allows a greatly increased data transfer rate between high-performance computers. The invention is inexpensive enough to bring high-speed video and data services to homes through a super modem.

  20. Security Administration Reports Application

    Data.gov (United States)

    Social Security Administration — Contains SSA Security Reports that allow Information Security Officers (ISOs) to access, review and take appropriate action based on the information contained in the...

  1. Special Administrative Jurisdictions

    Directory of Open Access Journals (Sweden)

    Vasilica Negruț

    2016-05-01

    Full Text Available The Constitution of Romania revised in 2003 establishes the free and voluntary nature of the special administrative jurisdictions, a fact which allows the party concerned to address either the administrative-judicial body or directly the court. If they opted for the administrative-judicial way, it must be followed to the end, then, under the terms established by the law, the party may address the court, under the right of access to justice provided by article 21 of the constitution. The administrative jurisdiction is an activity of solving an administrative litigation by specific procedural rules of judicial procedure, based on the principle of the independence, of insuring the right to defense and the administrative-jurisdictional independence activity, which results in a jurisdictional administrative act. In order to achieve the objectives of the paper, namely to highlight the essential elements of the resolution of litigation according to special administrative jurisdictions, we have achieved an analysis of the legislative acts referring to this activity, of the doctrine and jurisprudence. After examination and empirical research, the paper summarizes and specifies the general conclusions on the role and importance of special administrative courts.

  2. Lesotho - Land Administration Reform

    Data.gov (United States)

    Millennium Challenge Corporation — Michigan State University was assigned to design the impact evaluation (IE) of the Land Administration Reform Project (LARP) funded under the Millennium Challenge...

  3. Rehabilitation Services Administration

    Science.gov (United States)

    ... of Veterans Affairs, Equal Employment Opportunity Commission, National Council on Disability, Office of Personnel Management, and the Social Security Administration. This resource guide identifies relevant federal and federally ...

  4. Veterans Administration Databases

    Science.gov (United States)

    The Veterans Administration Information Resource Center provides database and informatics experts, customer service, expert advice, information products, and web technology to VA researchers and others.

  5. Ultrashort pulse laser technology laser sources and applications

    CERN Document Server

    Schrempel, Frank; Dausinger, Friedrich

    2016-01-01

    Ultrashort laser pulses with durations in the femtosecond range up to a few picoseconds provide a unique method for precise materials processing or medical applications. Paired with the recent developments in ultrashort pulse lasers, this technology is finding its way into various application fields. The book gives a comprehensive overview of the principles and applications of ultrashort pulse lasers, especially applied to medicine and production technology. Recent advances in laser technology are discussed in detail. This covers the development of reliable and cheap low power laser sources as well as high average power ultrashort pulse lasers for large scale manufacturing. The fundamentals of laser-matter-interaction as well as processing strategies and the required system technology are discussed for these laser sources with respect to precise materials processing. Finally, different applications within medicine, measurement technology or materials processing are highlighted.

  6. Trends Affecting Community College Library Administrators

    Science.gov (United States)

    Elizabeth W. Matthews

    1977-01-01

    A national survey of administrators in the resource centers of community colleges reveals that they are assuming a new expanded role in a total program. They are becoming educational technologists for individual and curricular instruction assisting in teaching strategies and becoming involved in areas such as design, production, graphics and…

  7. 21st Century Theories of Education Administration

    Science.gov (United States)

    Makolandra, Joseph; Bezy, Kevin G.; Delp, Cindy; Bizzell, Brad E.; Wray, Caroline; Jones, Forest; Womack, Janet; Hutton, Dawn; Jones, Asia; Wood-Setzer, Guylene; Williams, Seydric; Leonard, Nancy; Nicely, Ken; Wright, Linda; Pennington, Robert; Richardson, Tracy

    2009-01-01

    Educational administrative practitioners evaluate theories, implement practices, and refine leadership strategies daily. The exploration of the leadership gap between theory and praxis is a quantum undertaking. Leadership from the educational perspective takes many forms and presents many challenges. This document examines leadership from several…

  8. A New Selective Harmonic Elimination Pulse- Width and Amplitude Modulation (SHEPWAM) for Drive Applications

    DEFF Research Database (Denmark)

    Ghoreishy, Hoda; Varjani, Ali Yazdian; Mohamadian, Mustafa

    2013-01-01

    Compared to the conventional selective harmonic elimination-pulse width modulation (SHE-PWM), the selective harmonic elimination-pulse width and amplitude modulation (SHE-PWAM) control strategy results in significant improvements in the performance of CHB inverters. This fact is due to considerin...

  9. Control of high power IGBT modules in the active region for fast pulsed power converters

    CERN Document Server

    Cravero, J M; Garcia Retegui, R; Maestri, S; Uicich, G

    2014-01-01

    At CERN, fast pulsed power converters are used to supply trapezoidal current in different magnet loads. These converters perform output current regulation by using a high power IGBT module in its ohmic region. This paper presents a new strategy for pulsed current control applications using a specifically designed IGBT driver.

  10. Coiled transmission line pulse generators

    Energy Technology Data Exchange (ETDEWEB)

    McDonald, Kenneth Fox (Columbia, MO)

    2010-11-09

    Methods and apparatus are provided for fabricating and constructing solid dielectric "Coiled Transmission Line" pulse generators in radial or axial coiled geometries. The pour and cure fabrication process enables a wide variety of geometries and form factors. The volume between the conductors is filled with liquid blends of monomers, polymers, oligomers, and/or cross-linkers and dielectric powders; and then cured to form high field strength and high dielectric constant solid dielectric transmission lines that intrinsically produce ideal rectangular high voltage pulses when charged and switched into matched impedance loads. Voltage levels may be increased by Marx and/or Blumlein principles incorporating spark gap or, preferentially, solid state switches (such as optically triggered thyristors) which produce reliable, high repetition rate operation. Moreover, these Marxed pulse generators can be DC charged and do not require additional pulse forming circuitry, pulse forming lines, transformers, or an a high voltage spark gap output switch. The apparatus accommodates a wide range of voltages, impedances, pulse durations, pulse repetition rates, and duty cycles. The resulting mobile or flight platform friendly cylindrical geometric configuration is much more compact, light-weight, and robust than conventional linear geometries, or pulse generators constructed from conventional components. Installing additional circuitry may accommodate optional pulse shape improvements. The Coiled Transmission Lines can also be connected in parallel to decrease the impedance, or in series to increase the pulse length.

  11. Webmin administrator's cookbook

    CERN Document Server

    Karzynski, Michal

    2014-01-01

    Written in a cookbook format with practical recipes this book helps you to perform various administrative tasks using Webmin and enables you to perform common jobs more efficiently.This book is perfect for System administrators who want to learn more advanced concepts of Webmin and how it can help to set up a server for development, testing or deployment.

  12. The School Personnel Administrator.

    Science.gov (United States)

    Knox, Rodney F.

    This paper provides an overview of the development of the school-personnel administrator role. It first describes the influence of the science-management and human-relations movements and the behavioral sciences on personnel administration and human resource management. It next discusses the role of the personnel-performance-appraisal system and…

  13. Centos system administration essentials

    CERN Document Server

    Mallett, Andrew

    2014-01-01

    If you are a Linux administrator who is looking to gain knowledge that differentiates yourself from the crowd, then this is the book for you. Beginners who have a keen interest to learn more about Linux administration will also progress quickly with this resourceful learning guide.

  14. Tenure for Administrators?

    Science.gov (United States)

    Holyer, Robert

    2004-01-01

    The practice of granting tenure to academic administrators, especially presidents and academic deans, seems fairly prevalent. However, it is important to consider the possible advantages and disadvantages carefully before making such an offer. Boards interested in attracting talented administrators empowered to do what is in the best interest of…

  15. Postmodern Public Administration

    DEFF Research Database (Denmark)

    Bogason, Peter

    2005-01-01

    Discussion of the trends towards more uses of postmodern analysis within the discipline of public administration, particularly in the USA......Discussion of the trends towards more uses of postmodern analysis within the discipline of public administration, particularly in the USA...

  16. Administrative Theory in Transition.

    Science.gov (United States)

    Griffiths, Daniel E.

    This monograph analyzes transition in educational administrative theory. A brief introductory section describes the theoretical movement, the substance and repercussions of Thomas Greenfield's critique of educational administrative theory in 1974, and emerging qualitative approaches. Seven readings, all written by the volume's author, view…

  17. Improving Educational Administrative Decisions.

    Science.gov (United States)

    Wolfe, A. E.

    This paper discusses the financial crisis facing public education in the United States today and argues that the most effective response to this crisis is to improve the decision-making skills of educational administrators. Based on a review of the literature on administrative decision-making and organizational change, the author examines several…

  18. Food and Drug Administration

    Science.gov (United States)

    ... Health and Human Services U.S. Food and Drug Administration A to Z Index Follow FDA En Español ... Map Nondiscrimination Website Policies U.S. Food and Drug Administration 10903 New Hampshire Avenue Silver Spring, MD 20993 ...

  19. The Administrative Power Grab

    Science.gov (United States)

    Sorenson, Richard D.

    2007-01-01

    Administrative power for some school teachers can be an aphrodisiac that can be applied negatively, especially when a leader has devastating instinct for the weaknesses of others. A leader's intellect and heart closes shop and ceases to function when drunk on power. In this article, the author describes how the use of administrative power can be…

  20. Understanding land administration systems

    DEFF Research Database (Denmark)

    P. Williamson, Ian; Enemark, Stig; Wallace, Judy

    2008-01-01

    This paper introduces basic land administration theory and highlights four key concepts that are fundamental to understanding modern land administration systems. Readers may recall the first part of the paper in October issue of Coordinates. Here is the concluding part that focuses on the changing...

  1. Koncepcja lean administration

    OpenAIRE

    2010-01-01

    The article presents an attempt of description of Lean Administration concept. The pre- requisites and principles of Lean Administration system is given. Next, the functions and perspectives of “lean” activities are discussed together with methodological framework. The steps and auxiliary methods are also defined.

  2. Application of laser pulse stretching scheme for efficiently delivering laser energy in photoacoustic imaging

    Science.gov (United States)

    Wang, Tianheng; Kumavor, Patrick D.; Zhu, Quing

    2012-06-01

    High-energy and short-duration laser pulses are desirable to improve the photoacoustic image quality when imaging deeply seated lesions. In many clinical applications, the high-energy pulses are coupled to tissue using optical fibers. These pulses can damage fibers if the damage threshold is exceeded. While keeping the total energy under the Food and Drug Administration limit for avoiding tissue damage, it is necessary to reduce the peak intensity and increase the pulse duration for minimizing fiber damage and delivering sufficient light for imaging. We use laser-pulse-stretching to address this problem. An initial 17-ns pulse was stretched to 27 and 37 ns by a ring-cavity laser-pulse-stretching system. The peak power of the 37-ns stretched pulse reduced to 42% of the original, while the fiber damage threshold was increased by 1.5-fold. Three ultrasound transducers centered at 1.3-, 3.5-, and 6-MHz frequencies were simulated, and the results showed that the photoacoustic signal of a 0.5-mm-diameter target obtained with 37-ns pulse was about 98, 91, and 80%, respectively, using the same energy as the 17-ns pulse. Simulations were validated using a broadband hydrophone. Quantitative comparisons of photoacoustic images obtained with three corresponding transducers showed that the image quality was not affected by stretching the pulse.

  3. Green Light Pulse Oximeter

    Energy Technology Data Exchange (ETDEWEB)

    Scharf, John Edward (Oldsmar, FL)

    1998-11-03

    A reflectance pulse oximeter that determines oxygen saturation of hemoglobin using two sources of electromagnetic radiation in the green optical region, which provides the maximum reflectance pulsation spectrum. The use of green light allows placement of an oximetry probe at central body sites (e.g., wrist, thigh, abdomen, forehead, scalp, and back). Preferably, the two green light sources alternately emit light at 560 nm and 577 nm, respectively, which gives the biggest difference in hemoglobin extinction coefficients between deoxyhemoglobin, RHb, and oxyhemoglobin, HbO.sub.2.

  4. Pulsed differential pumping system

    Energy Technology Data Exchange (ETDEWEB)

    Antipov, G.N.; Bagautdinov, F.A.; Rybalov, S.V.

    1985-06-01

    A pulsed differential pumping system is described for extracting an electron beam from a shaping region at a pressure of 10/sup -5/ torr into a volume with a pressure of 10-100 torr. A fast valve is used with appropriate geometrical parameters to reduce the length of the outlet channel considerable while increasing its diameter. Test results are given. The pumping system has two sections which communicate one with the other and with the volume at the elevated pressure which is produced by gasdynamic nozzles.

  5. Pulse Field Gel Electrophoresis.

    Science.gov (United States)

    Sharma-Kuinkel, Batu K; Rude, Thomas H; Fowler, Vance G

    2016-01-01

    Pulse Field Gel Electrophoresis (PFGE) is a powerful genotyping technique used for the separation of large DNA molecules (entire genomic DNA) after digesting it with unique restriction enzymes and applying to a gel matrix under the electric field that periodically changes direction. PFGE is a variation of agarose gel electrophoresis that permits analysis of bacterial DNA fragments over an order of magnitude larger than that with conventional restriction enzyme analysis. It provides a good representation of the entire bacterial chromosome in a single gel with a highly reproducible restriction profile, providing clearly distinct and well-resolved DNA fragments.

  6. A Pulsed Sphere Tutorial

    Energy Technology Data Exchange (ETDEWEB)

    Cullen, Dermott E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2017-01-30

    Here I attempt to explain what physically happens when we pulse an object with neutrons, specifically what we expect the time dependent behavior of the neutron population to look like. Emphasis is on the time dependent emission of both prompt and delayed neutrons. I also describe how the TART Monte Carlo transport code models this situation; see the appendix for a complete description of the model used by TART. I will also show that, as we expect, MCNP and MERCURY, produce similar results using the same delayed neutron model (again, see the appendix).

  7. On-line comprehensive two-dimensional HepG2 cell membrane chromatographic analysis system for charactering anti-hepatoma components from rat serum after oral administration of Radix scutellariae: A strategy for rapid screening active compounds in vivo.

    Science.gov (United States)

    Jia, Dan; Chen, Xiaofei; Cao, Yan; Wu, Xunxun; Ding, Xuan; Zhang, Hai; Zhang, Chuan; Chai, Yifeng; Zhu, Zhenyu

    2016-01-25

    Cell membrane chromatography (CMC) is a bioaffinity chromatography technique for characterizing interactions between drugs and membrane receptors and has been widely used to screen active components from complex samples such as herbal medicines (HMs). However, it has never been applied in vivo due to its relatively high limit of detection (LOD) and the matrix interferences. In this study, a novel on-line comprehensive two-dimensional HepG2/CMC/enrich columns/high performance liquid chromatography/time-of-flight mass spectrometry system was developed to rapidly screen potential anti-hepatoma components from drug-containing serum of rats after oral administration of Radix scutellariae. A matrix interference deduction method with a home-written program in MATLAB was developed, which could successfully eliminate the interference of endogenous substances in serum. Baicalein, wogonin, chrysin, oroxylin A, neobaicalein and rivularin from Radix scutellariae extraction were significantly retained in the HepG2/CMC column. Three potential active components, wogonin, oroxylin A and neobaicalein were firstly screened from the drug-containing serum as well. The cell counting kit-8 assay demonstrated that wogonin, oroxylin A and chrysin showed high inhibitory activities in a dose-dependent manner on HepG2 cells at the concentration of 12.5-200 μM (pactive components from complex biological samples and could be applied to other biochromatography models.

  8. Studies on Educational Administrations Strategies for Running Schools with Distinctive Features in the CAPF Academies%武警院校教务工作适应特色办学对策研究

    Institute of Scientific and Technical Information of China (English)

    叶文芳

    2011-01-01

    在当前武警院校“深化教学改革,实施特色办学”的大趋势下,院校教务部门应充分发挥谋划作用,认真研究特色办学的总体思路;充分发挥指导作用,科学探索特色办学的实现途径;充分发挥管控作用,积极创造特色办学的有利条件;充分发挥协调作用,科学统筹特色办学的各种关系。%Nowadays, in the overall trend of "deepening reform of teaching, running a school with unique feature", the educational administration of a CAPF academy should give full play to the actions of schemes, research the chief mentality of running a school with unique feature seriously; and give full play to the functions of guiding, explore approaches to run a school with unique feature scientifically; in the mean time, it also should give full play to the roles of control, creative the advantages of running a school with unique feature actively; and give full play to the effects of coordinate, arrange all kinds of relations in running a school with unique feature rationally.

  9. National Drug Control Strategy, 2011

    Science.gov (United States)

    Office of National Drug Control Policy, 2011

    2011-01-01

    In May of 2010, President Obama released the Administration's inaugural "National Drug Control Strategy". Based on the premise that drug use and its consequences pose a threat not just to public safety, but also to public health, the 2010 "Strategy" represented the first comprehensive rebalancing of Federal drug control policy in the nearly 40…

  10. Methylprednisolone pulse therapy in severe dysthyroid optic neuropathy

    Energy Technology Data Exchange (ETDEWEB)

    Guy, J.R.; Fagien, S.; Donovan, J.P.; Rubin, M.L. (Univ. of Florida, Gainesville (USA))

    1989-07-01

    Five patients with severe dysthyroid optic neuropathy were treated with intravenous methylprednisolone (1 g daily for 3 consecutive days). Before administration, visual acuity of the more severely affected eyes of each patient was counting fingers at 5 feet, 8/200, 20/400, 20/200, and 20/80. Immediately after completion of pulse therapy, visual acuity improved to 20/25 in four patients and 20/30 in one. Remissions were maintained with oral prednisone and external beam irradiation of the orbit. Pulse methylprednisolone therapy appears to be beneficial in the initial management of severe dysthyroid optic neuropathy.

  11. COMPUTER BASED HEART PULSES MEASUREMENT

    Directory of Open Access Journals (Sweden)

    Ali N. Hamoodi

    2013-05-01

    Full Text Available In this work the measurement and displays of blood oxygen saturation and pulse rate are investigated practically using computer.The analysis involves the variation in blood oxygen saturation ratio and pulse rate. The results obtained are compared with kontron pulse oximeter 7840 device. The value obtained for the same person pulse rate is approximately equal to that obtained by the konton pulse oximeter 7840 device. The sensor used in this work is the finger clip.The advantages of using computer over kontron pulse oximeter 7840 device is that the data of the patient can be saved in the computer for many years and also it can be display at any time so that the doctor get file contains all data for each patient. 

  12. Angular momentum of sound pulses.

    Science.gov (United States)

    Lekner, John

    2006-07-05

    Three-dimensionally localized acoustic pulses in an isotropic fluid medium necessarily have transverse components of momentum density. Those with an azimuthal component of momentum density can carry angular momentum. The component of total pulse angular momentum along the direction of the total momentum is an invariant (constant in time and independent of choice of origin). The pulse energy, momentum and angular momentum are evaluated analytically for a family of localized solutions of the wave equation. In the limit where the pulses have many oscillations within their spatial extent ([Formula: see text], where k is the wavenumber and a determines the size of a pulse), the energy, momentum and angular momentum are consistent with a multiphonon representation of the pulse, each phonon having energy [Formula: see text], momentum [Formula: see text] and angular momentum [Formula: see text] (with integer m).

  13. Bipolar pulse forming line

    Science.gov (United States)

    Rhodes, Mark A.

    2008-10-21

    A bipolar pulse forming transmission line module for linear induction accelerators having first, second, third, fourth, and fifth planar conductors which form an interleaved stack with dielectric layers between the conductors. Each conductor has a first end, and a second end adjacent an acceleration axis. The first and second planar conductors are connected to each other at the second ends, the fourth and fifth planar conductors are connected to each other at the second ends, and the first and fifth planar conductors are connected to each other at the first ends via a shorting plate adjacent the first ends. The third planar conductor is electrically connectable to a high voltage source, and an internal switch functions to short a high voltage from the first end of the third planar conductor to the first end of the fourth planar conductor to produce a bipolar pulse at the acceleration axis with a zero net time integral. Improved access to the switch is enabled by an aperture through the shorting plate and the proximity of the aperture to the switch.

  14. Heat driven pulse pump

    Science.gov (United States)

    Benner, Steve M (Inventor); Martins, Mario S. (Inventor)

    2000-01-01

    A heat driven pulse pump includes a chamber having an inlet port, an outlet port, two check valves, a wick, and a heater. The chamber may include a plurality of grooves inside wall of the chamber. When heated within the chamber, a liquid to be pumped vaporizes and creates pressure head that expels the liquid through the outlet port. As liquid separating means, the wick, disposed within the chamber, is to allow, when saturated with the liquid, the passage of only liquid being forced by the pressure head in the chamber, preventing the vapor from exiting from the chamber through the outlet port. A plurality of grooves along the inside surface wall of the chamber can sustain the liquid, which is amount enough to produce vapor for the pressure head in the chamber. With only two simple moving parts, two check valves, the heat driven pulse pump can effectively function over the long lifetimes without maintenance or replacement. For continuous flow of the liquid to be pumped a plurality of pumps may be connected in parallel.

  15. Assembly delay line pulse generators

    CERN Document Server

    1971-01-01

    Assembly of six of the ten delay line pulse generators that will power the ten kicker magnet modules. One modulator part contains two pulse generators. Capacitors, inductances, and voltage dividers are in the oil tank on the left. Triggered high-pressure spark gap switches are on the platforms on the right. High voltage pulse cables to the kicker magnet emerge under the spark gaps. In the centre background are the assembled master gaps.

  16. Multi pulse control of entanglement

    CERN Document Server

    Uchiyama, C; Uchiyama, Chikako; Aihara, Masaki

    2004-01-01

    We study the effectiveness of multi pulse control to suppress the degradation of entanglement. Based on a linearly interacting spin-boson model, we show that the multi pulse application recovers the decay of concurrence when an entangled pair of spins interacts with a reservoir that has the non-Markovian nature. We present the effectiveness of multi pulse control for both the common bath case and the individual bath case.

  17. BRAZILIAN ADMINISTRATION, ADMINISTRATIVE REFORM AND THE NEW STATE: THE ROLE OF ADMINISTRATIVE APPARATUS IN VARGAS ADMINISTRATION

    Directory of Open Access Journals (Sweden)

    Emerson Moura

    2016-07-01

    Full Text Available The role played by the administrative apparatus through the Department of Administrative Services in the Government policy Vargas is the object put in debate. Analyzes the theme from the the investigation of patrimonial, authoritarian and inefficient context which marks the formation and development of administrative bureaucracy, the tenders of professionalization and efficiency brought by the administrative reforms of the 1930s and 1940s with the contrast of the limitations of the import of the Weberian model in the Brazilian context and analysis of the establishment of the New State DASP and their assignments. Search the work demonstrate the control position he held directly and through the State Departments in the Brazilian Public Administration ensuring centralized and developmental policy of the government. For this is adopted as the research method of approach structuralism in order to identify the deconstruction of the phenomenon - of administrative reforms - in the superficial perception - the proposed impersonality and efficiency as the best way of achieving the public interest - its invariant structure - the search for the adequacy of the administrative apparatus and bureaucracy for pursuit of political ends pursued by the Government.

  18. New Strategy That Delays Progression of Amyotrophic Lateral Sclerosis in G1H-G93A Transgenic Mice: Oral Administration of Xanthine Oxidoreductase Inhibitors That Are Not Substrates for the Purine Salvage Pathway.

    Science.gov (United States)

    Kato, Shinsuke; Kato, Masako; Kusano, Teruo; Nishino, Takeshi

    2016-12-01

    Amyotrophic lateral sclerosis (ALS), Lou Gehrig's disease, is a progressive fatal neurodegenerative disease that involves both upper and lower motor neurons. We orally administered 4 xanthine oxidoreductase (XOR) inhibitors to G1H-G93A mice carrying 25 transgene copy numbers of human mutant G93A superoxide dismutase 1, from 80 days of age. Three nonpurine-analogue inhibitors (TEI-6720: Febuxostat, Y-700 and FYX-051), but not allopurinol with a purine analogue ring (pyrazolo pyrimidine ring), significantly delayed disease onset, prolonged survival and the duration of disease stages, improved clinical signs, and alleviated weight loss. Exercise testing (extension reflex, inclined plane, footprint, rotarod, and beam balance tests) showed significantly improved motor function in the G1H-G93A mice treated with these 3 inhibitors. Significant amelioration of disease was seen even when TEI-6720 or Y-700 was administered after the appearance of early signs. Histopathological evaluation in the late stage revealed that G1H-G93A mice treated with TEI-6720 had well-preserved motor neurons and fewer inclusion bodies, compared with mice treated with placebo or with allopurinol. Our results indicate that these 3 nonpurine-analogue XOR inhibitors might increase the supply of high-energy compounds via the purine salvage pathway, thereby protecting motor neurons against death. This strategy may be applicable for oral therapy of ALS patients. © 2016 American Association of Neuropathologists, Inc. All rights reserved.

  19. Analysis of Pulse Modulated Control Systems (Ⅲ) Stability of Systems with Pulse Frequency Modulation and Systems with Combined Pulse Frequency and Pulse Width Modulation

    OpenAIRE

    OI,Shigemitsu

    1993-01-01

    Sufficient conditions for finite pulse stability of interconnected systems with combined pulse frequency and pulse width modulation are developed in this paper using a direct method. The stability criteria established provide upper bounds on the number of pulses emitted by each modulator. The results are also applicable to those systems which contain a finite number of pulse frequency modulators and a finite number of combined pulse frequency and pulse width modulators

  20. Population inversion by chirped pulses

    Energy Technology Data Exchange (ETDEWEB)

    Lu Tianshi [Department of Mathematics and Statistics, Wichita State University, Wichita, Kansas 67260-0033 (United States)

    2011-09-15

    In this paper, we analyze the condition for complete population inversion by a chirped pulse over a finite duration. The nonadiabatic transition probability is mapped in the two-dimensional parameter space of coupling strength and detuning amplitude. Asymptotic forms of the probability are derived by the interference of nonadiabatic transitions for sinusoidal and triangular pulses. The qualitative difference between the maps for the two types of pulses is accounted for. The map is used for the design of stable inversion pulses under specific accuracy thresholds.

  1. Double pulse laser wakefield accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Changbum [Department of Physics, Pohang University of Science and Technology, Pohang 790-784 (Korea, Republic of)], E-mail: chbkim@postech.ac.kr; Kim, Jin-Cheol B. [Department of Physics, Pohang University of Science and Technology, Pohang 790-784 (Korea, Republic of); Kim, Kukhee [National Fusion Reserch Center, Daejeon 305-333 (Korea, Republic of); Ko, In Soo [Department of Physics, Pohang University of Science and Technology, Pohang 790-784 (Korea, Republic of); Suk, Hyyong [Center for Advanced Accelerators, Korea Electrotechnology Research Institute, Changwon 641-120 (Korea, Republic of)

    2007-10-22

    Two-dimensional simulation studies are performed for modified laser wakefield acceleration. After one laser pulse, another identical laser pulse is sent to the plasma to amplify the wake wave resonantly. The simulation results show that the number of injected electrons is bigger than that of the single pulse case and the beam energy is higher as well. In addition, increase of the transverse amplitude is noticed in the wake wave after the second laser pulse. This shows that the transverse motion of the wake wave enhances the wave breaking for strong injection and acceleration of electron beams.

  2. Pulse oximetry in severe anaemia

    DEFF Research Database (Denmark)

    Ramsing, T; Rosenberg, J

    1992-01-01

    Measurement of arterial oxygen saturation by pulse oximetry was performed in two patients with acute and chronic anaemia (haemoglobin concentrations: 2.9 mmol/l (4.7 g/dl) and 1.9 mmol/l (3.0 g/dl), respectively) using a Radiometer OXI and a Nellcor N-200 pulse oximeter. The two oximeters read...... alternating different values in the two patients. In conclusion, pulse oximeters are able to give a value for oxygen saturation even at extreme anaemia, and when a high value is given, it possibly reflects arterial oxygen saturation. The value of pulse oximetry in severe anaemia is discussed....

  3. Publication of administrative circular

    CERN Multimedia

    HR Department

    2009-01-01

    ADMINISTRATIVE CIRCULAR NO. 23 (REV. 2) – SPECIAL WORKING HOURS Administrative Circular No. 23 (Rev. 2) entitled "Special working hours", approved following discussion in the Standing Concertation Committee on 9 December 2008, will be available on the intranet site of the Human Resources Department as from 19 December 2008: http://cern.ch/hr-docs/admincirc/admincirc.asp It cancels and replaces Administrative Circular No. 23 (Rev. 1) entitled "Stand-by duty" of April 1988. A "Frequently Asked Questions" information document on special working hours will also be available on this site. Paper copies of this circular will shortly be available in Departmental Secretariats. Human Resources Department Tel. 78003

  4. PUBLICATION OF ADMINISTRATIVE CIRCULAR

    CERN Multimedia

    HR Department

    2008-01-01

    ADMINISTRATIVE CIRCULAR NO. 23 (REV. 2) – SPECIAL WORKING HOURS Administrative Circular No. 23 (Rev. 2) entitled "Special working hours", approved following discussion in the Standing Concertation Committee meeting of 9 December 2008, will be available on the intranet site of the Human Resources Department as from 19 December 2008: http://cern.ch/hr-docs/admincirc/admincirc.asp It cancels and replaces Administrative Circular No. 23 (Rev. 1) entitled "Stand-by duty" of April 1988. A "Frequently Asked Questions" information document on special working hours will also be available on this site. Paper copies of this circular will shortly be available in departmental secretariats. Human Resources Department Tel. 78003

  5. Administration and Jurisdictional Policy

    Directory of Open Access Journals (Sweden)

    Eduardo Hernando Nieto

    2009-06-01

    Full Text Available To what extent does studying jurisdictional politics need the knowledge of different administrative theories in general and the science of public administration in particular? This small text proposes such reflection and comes to the conclusion that it is impossible to propose a new approximation to this topic without considering the administrative theory, for that the specialists and thinkers will get more with the contact of this discipline from what it is called a multidisciplinary approach.

  6. Theoretical Studies of the Output Pulse with Variation of the Pumping Pulse for RF Excited CO2 Pulsed Waveguide Laser

    Institute of Scientific and Technical Information of China (English)

    A Rauf; ZHOU Wei; XIN Jian-guo

    2006-01-01

    The behavior of a RF-excited waveguide CO2 laser in the pulse regime is studied theoretically. The output pulse evolution is studied by applying three types of pulses namely the square, sine and the triangular ones as the excitation pulses. The frequency dependence behavior of the output pulse is also presented.

  7. Administrative Discretionary Grant Data

    Data.gov (United States)

    Institute of Museum and Library Services — This dataset of administrative records contains discretionary grant recipients who were awarded funds by the Institute of Museum and Library Services from fiscal...

  8. Territorial Administrative Budgetary Structure

    Directory of Open Access Journals (Sweden)

    Lucia Risti

    2011-06-01

    Full Text Available Local budget structure is a consequence of the way the country’s venues are organized from the territorial administrative point of view, in communes, towns, municipalities and the capital, Bucharest, in districts.

  9. Attrition of College Administrators

    Science.gov (United States)

    Lindahl, Charles W.

    1973-01-01

    Suggests that many high-level administrators in colleges are leaving their posts because of the physical, emotional, and mental demands made upon them and because of the complex issues facing higher education. (DS)

  10. Social Security Administration

    Science.gov (United States)

    ... Languages Sign in / up The United States Social Security Administration Cost-Of-Living Adjustment (COLA) Information about ... replacement Medicare card Change of Address my Social Security Check out your Social Security Statement , change your ...

  11. Scientists vs. the administration

    CERN Multimedia

    2004-01-01

    Article denouncing the supposed impartiality of signatories of a report released by the Union of Concerned Scientists (UCS), which accused the Bush administration of systemically suborning objective science to a political agenda (1 page).

  12. The Administrator Selection Process

    Science.gov (United States)

    Griffin, Michael F.

    1974-01-01

    Proposes that education establish for administrators systematic, rigorous, albeit subjective, selection procedures that recognize the principle of organizational democracy and the public nature of the educational enterprise. (Author/DN)

  13. Administrative Law Judges

    Science.gov (United States)

    The Administrative Law Judges conduct hearings and render decisions in proceedings between the EPA and persons, businesses, government entities, and other organizations which are or are alleged to be regulated under environmental laws.

  14. Understanding land administration systems

    DEFF Research Database (Denmark)

    P. Williamson, Ian; Enemark, Stig; Wallace, Judy

    2008-01-01

    in contributing to sustainable development, thirdly the changing nature of ownership and the role of land markets, and lastly a land management vision that promotes land administration in support of sustainable development and spatial enablement of society. We present here the first part of the paper. The second...... part focuses on the changing  role of ownership and the role of land markets, and a land management vision will be published in November issue of Coordinates. Udgivelsesdato: Oktober......This paper introduces basic land administration theory and highlights four key concepts that are fundamental to understanding modern land administration systems - firstly the land management paradigm and its influence on the land administration framework, secondly the role that the cadastre plays...

  15. Food and Drug Administration

    Science.gov (United States)

    ... trials, Critical Path Initiative and more Icon for Business & Industry section. For Industry Guidance, registration and listing, ... Map Nondiscrimination Website Policies U.S. Food and Drug Administration 10903 New Hampshire Avenue Silver Spring, MD 20993 ...

  16. Administrative & Operational Circulars - Reminder

    CERN Multimedia

    HR Department

    2011-01-01

    All Administrative and Operational Circulars are available on the intranet site of the Human Resources Department at the following address: http://cern.ch/hr-docs/admincirc/admincirc.asp Department Head Office  

  17. Spatially enabled land administration

    DEFF Research Database (Denmark)

    Enemark, Stig

    2006-01-01

    . In other words: Good governance and sustainable development is not attainable without sound land administration or - more broadly – sound land management. The paper presents a land management vision that incorporates the benefits of ICT enabled land administration functions. The idea is that spatial...... enabling of land administration systems managing tenure, valuation, planning, and development will allow the information generated by these activities to be much more useful. Also, the services available to private and public sectors and to community organisations should commensurably improve. Knowledge...... the communication between administrative systems and also establish more reliable data due to the use the original data instead of copies. In Denmark, such governmental guidelines for a service-oriented ITarchitecture in support of e-government are recently adopted. Finally, the paper presents the role of FIG...

  18. Veterans Health Administration (VHA)

    Data.gov (United States)

    Social Security Administration — The purpose of this agreement is for SSA to verify SSNs and other identifying information for the Department of Veterans Affairs, VHA. DVA will use the information...

  19. Learning Cassandra for administrators

    CERN Document Server

    Parthasarathy, Vijay

    2013-01-01

    This book is a practical, hands-on guide, taking the reader from the basics of using Cassandra though to the installation and the running.Learning Cassandra for Administrators is for administrators who manage a large deployment of Cassandra clusters, and support engineers who would like to install the monitoring tools and who are also in charge of making sure the cluster stays the same, ensuring that the service is always up and running.

  20. Administration and environmental protection

    OpenAIRE

    Milkov, Dragan

    2013-01-01

    Environmental protection is a very important task of the state. The state in this area deals in a preventative manner, and at the same time controls the application of laws and regulations. The aim of this paper is to carry out the identification of administrative bodies dealing with environmental protection at the national, provincial and local levels. There are administrative bodies dealing directly with matters of environmental protection. On the other hand, within the scope of some admini...

  1. SELinux policy administration

    CERN Document Server

    Vermeulen, Sven

    2013-01-01

    A step-by-step guide to learn how to set up security on Linux servers by taking SELinux policies into your own hands.Linux administrators will enjoy the various SELinux features that this book covers and the approach used to guide the admin into understanding how SELinux works. The book assumes that you have basic knowledge in Linux administration, especially Linux permission and user management.

  2. Coherent control with shaped femtosecond laser pulses applied to ultracold molecules

    CERN Document Server

    Salzmann, W; Wester, R; Weidemüller, M; Merli, A; Weber, S M; Sauer, F; Plewicki, M; Weise, F; Esparza, A M; Wöste, L; Lindinger, A; Salzmann, Wenzel; Poschinger, Ulrich; Wester, Roland; Weidemueller, Matthias; Merli, Andrea; Weber, Stefan M.; Sauer, Franziska; Plewicki, Mateusz; Weise, Fabian; Esparza, Aldo Mirabal; Woeste, Ludger; Lindinger, Albrecht

    2005-01-01

    We report on coherent control of excitation processes of translationally ultracold rubidium dimers in a magneto-optical trap by using shaped femtosecond laser pulses. Evolution strategies are applied in a feedback loop in order to optimize the photoexcitation of the Rb2 molecules, which subsequently undergo ionization or fragmentation. A superior performance of the resulting pulses compared to unshaped pulses of the same pulse energy is obtained by distributing the energy among specific spectral components. The demonstration of coherent control to ultracold ensembles opens a path to actively influence fundamental photo-induced processes in molecular quantum gases.

  3. Global Strategy

    DEFF Research Database (Denmark)

    Li, Peter Ping

    2013-01-01

    Global strategy differs from domestic strategy in terms of content and process as well as context and structure. The content of global strategy can contain five key elements, while the process of global strategy can have six major stages. These are expounded below. Global strategy is influenced...... by rich and complementary local contexts with diverse resource pools and game rules at the national level to form a broad ecosystem at the global level. Further, global strategy dictates the interaction or balance between different entry strategies at the levels of internal and external networks....

  4. Pulsed plasma arc cladding

    Institute of Scientific and Technical Information of China (English)

    龙; 白钢; 李振民; 张赋升; 杨思乾

    2004-01-01

    A prototype of Pulsed Plasma Arc Cladding system was developed, in which single power source supplies both transferred plasma arc (TPA) and non-transferred plasma arc (N-TPA). Both plasmas work in turn in a high frequency controlled by an IGBT connecting nozzle and workpiece. The working frequency of IGBT ranges from 50 ~ 7000Hz, in which the plasmas can work in turn smoothly. Higher than 500 Hz of working frequency is suggested for promotion of cladding quality and protection of IGBT. Drag phenomenon of TPA intensifies as the frequency goes up, which tends to increase the current proportion of TPA and suppress N-TPA. The occupation ratio of IGBT can be regulated from 5% ~ 95%, which balances the power supplies of both plasmas. An occupation ratio higher than 50% gives adequate proportion of arc current for N-TPA to preheat powder.

  5. Nanofabrication with Pulsed Lasers

    Directory of Open Access Journals (Sweden)

    Kabashin AV

    2010-01-01

    Full Text Available Abstract An overview of pulsed laser-assisted methods for nanofabrication, which are currently developed in our Institute (LP3, is presented. The methods compass a variety of possibilities for material nanostructuring offered by laser–matter interactions and imply either the nanostructuring of the laser-illuminated surface itself, as in cases of direct laser ablation or laser plasma-assisted treatment of semiconductors to form light-absorbing and light-emitting nano-architectures, as well as periodic nanoarrays, or laser-assisted production of nanoclusters and their controlled growth in gaseous or liquid medium to form nanostructured films or colloidal nanoparticles. Nanomaterials synthesized by laser-assisted methods have a variety of unique properties, not reproducible by any other route, and are of importance for photovoltaics, optoelectronics, biological sensing, imaging and therapeutics.

  6. Nanosecond Pulse Technique

    Science.gov (United States)

    1989-03-17

    tunnel diodes, to ferrites, etc.) and to the need for the review of the methods of formation and converting the pulses, to a considerable degree...4n3l) 0 1 + 4n 21)2 + (4n2l) (.84) _ 4 nf tl 5 (I - 4n12/) 2 - (4nil)’ (1.85) " ( - 2o) l - 4’n2% 2 I3 (I + 4n =2/)2 + ( 41a2 )’ -arg + 4ni,21. + j4na,tJ...recirculator is borrowed from the article of Yu. I. Neymark, Yu. K. Maklakov and L. P. Yelkins [105]. ENDFOOTNOTE. DOC = 88076720 PAGE d a) t l I t S6) t�t

  7. Nanofabrication with pulsed lasers.

    Science.gov (United States)

    Kabashin, Av; Delaporte, Ph; Pereira, A; Grojo, D; Torres, R; Sarnet, Th; Sentis, M

    2010-02-24

    An overview of pulsed laser-assisted methods for nanofabrication, which are currently developed in our Institute (LP3), is presented. The methods compass a variety of possibilities for material nanostructuring offered by laser-matter interactions and imply either the nanostructuring of the laser-illuminated surface itself, as in cases of direct laser ablation or laser plasma-assisted treatment of semiconductors to form light-absorbing and light-emitting nano-architectures, as well as periodic nanoarrays, or laser-assisted production of nanoclusters and their controlled growth in gaseous or liquid medium to form nanostructured films or colloidal nanoparticles. Nanomaterials synthesized by laser-assisted methods have a variety of unique properties, not reproducible by any other route, and are of importance for photovoltaics, optoelectronics, biological sensing, imaging and therapeutics.

  8. Pulsed plasma electron sourcesa)

    Science.gov (United States)

    Krasik, Ya. E.; Yarmolich, D.; Gleizer, J. Z.; Vekselman, V.; Hadas, Y.; Gurovich, V. Tz.; Felsteiner, J.

    2009-05-01

    There is a continuous interest in research of electron sources which can be used for generation of uniform electron beams produced at E ≤105 V/cm and duration ≤10-5 s. In this review, several types of plasma electron sources will be considered, namely, passive (metal ceramic, velvet and carbon fiber with and without CsI coating, and multicapillary and multislot cathodes) and active (ferroelectric and hollow anodes) plasma sources. The operation of passive sources is governed by the formation of flashover plasma whose parameters depend on the amplitude and rise time of the accelerating electric field. In the case of ferroelectric and hollow-anode plasma sources the plasma parameters are controlled by the driving pulse and discharge current, respectively. Using different time- and space-resolved electrical, optical, spectroscopical, Thomson scattering and x-ray diagnostics, the parameters of the plasma and generated electron beam were characterized.

  9. Micro pulse lidar

    Science.gov (United States)

    Spinhirne, James D.

    1993-01-01

    An eye safe, compact, solid state lidar for profiling atmospheric cloud and aerosol scattering has been demonstrated. The transmitter of the micropulse lidar is a diode pumped micro-J pulse energy, high repetition rate Nd:YLF laser. Eye safety is obtained through beam expansion. The receiver employs a photon counting solid state Geiger mode avalanche photodiode detector. Data acquisition is by a single card multichannel scaler. Daytime background induced quantum noise is controlled by a narrow receiver field-of-view and a narrow bandwidth temperature controlled interference filter. Dynamic range of the signal is limited by optical geometric signal compression. Signal simulations and initial atmospheric measurements indicate that systems built on the micropulse lidar concept are capable of detecting and profiling all significant cloud and aerosol scattering through the troposphere and into the stratosphere. The intended applications are scientific studies and environmental monitoring which require full time, unattended measurements of the cloud and aerosol height structure.

  10. Capacitor discharge pulse analysis.

    Energy Technology Data Exchange (ETDEWEB)

    Baker, Michael Sean; Griffiths, Stewart K.; Tanner, Danelle Mary

    2013-08-01

    Capacitors used in firing sets and other high discharge current applications are discharge tested to verify performance of the capacitor against the application requirements. Parameters such as capacitance, inductance, rise time, pulse width, peak current and current reversal must be verified to ensure that the capacitor will meet the application needs. This report summarizes an analysis performed on the discharge current data to extract these parameters by fitting a second-order system model to the discharge data and using this fit to determine the resulting performance metrics. Details of the theory and implementation are presented. Using the best-fit second-order system model to extract these metrics results in less sensitivity to noise in the measured data and allows for direct extraction of the total series resistance, inductance, and capacitance.

  11. Template Reproduction of GRB Pulse Light Curves

    Science.gov (United States)

    Hakkila, Jon E.; Preece, R. D.; Loredo, T. J.; Wolpert, R. L.; Broadbent, M. E.

    2014-01-01

    A study of well-isolated pulses in gamma ray burst light curves indicates that simple models having smooth and monotonic pulse rises and decays are inadequate. Departures from the Norris et al. (2005) pulse shape are in the form of a wave-like pre-peak residual that is mirrored and stretched following the peak. Pulse shape departures are present in GRB pulses of all durations, but placement of the departures relative to pulse peaks correlates with asymmetry. This establishes an additional link between temporal structure and spectral evolution, as pulse asymmetry is related to initial hardness while pulse duration indicates the rate of hard-to-soft pulse evolution.

  12. Research agenda shrimp pulse fishery

    NARCIS (Netherlands)

    Marlen, van B.; Rasenberg, M.M.M.; Verschueren, B.; Polet, H.

    2015-01-01

    In the recent decennia, many developments have taken place to improve the selectivity of the shrimp fishing gears. Recently, the development of a pulse gear for catching shrimps has taken up again as an opportunity to decrease discards, inspired by developments in the flatfish pulse fishery.

  13. Pulse oximetry for perioperative monitoring

    DEFF Research Database (Denmark)

    Pedersen, Tom; Møller, Ann Merete; Hovhannisyan, Karen

    2009-01-01

    Pulse oximetry is extensively used in the perioperative period and might improve patient outcomes by enabling an early diagnosis and, consequently, correction of perioperative events that might cause postoperative complications or even death. Only a few randomized clinical trials of pulse oximetry...

  14. A Single-Pulse Integrator

    DEFF Research Database (Denmark)

    Miller, Arne

    1974-01-01

    A single-pulse integrator is described. It gives a relative measure of the integral of the output signal from a coil monitor on the Risø 10 MeV linear accelerator, and displays the value on a digital voltmeter. The reproduccibility is found to be better than ±1% for an accelerated pulse charge...

  15. NMR in pulsed magnetic field

    KAUST Repository

    Abou-Hamad, Edy

    2011-09-01

    Nuclear magnetic resonance (NMR) experiments in pulsed magnetic fields up to 30.4 T focused on 1H and 93Nb nuclei are reported. Here we discuss the advantage and limitation of pulsed field NMR and why this technique is able to become a promising research tool. © 2011 Elsevier Inc. All Rights Reserved.

  16. Dexamethasone pulse therapy in pemphigus

    NARCIS (Netherlands)

    Toth, GG; van de Meer, JB; Jonkman, MF

    2002-01-01

    Pulse therapy with high-dose glucocorticoids was introduced 20 years ago as a treatment modality for autoimmune disease and transplant rejection. The most popular dermatological indication for pulse therapy is severe pemphigus. We reviewed the sequelae of 14 patients with pemphigus who were treated

  17. Pulse oximetry for perioperative monitoring

    DEFF Research Database (Denmark)

    Pedersen, Tom; Nicholson, Amanda; Hovhannisyan, Karen

    2014-01-01

    . Results indicated that hypoxaemia was reduced in the pulse oximetry group, both in the operating theatre and in the recovery room. During observation in the recovery room, the incidence of hypoxaemia in the pulse oximetry group was 1.5 to three times less. Postoperative cognitive function was independent...... postoperative complications or even death. Only a few randomized clinical trials of pulse oximetry during anaesthesia and in the recovery room have been performed that describe perioperative hypoxaemic events, postoperative cardiopulmonary complications and cognitive dysfunction. OBJECTIVES: To study the use...... checked the reference lists of trials and review articles. The original search was performed in January 2005, and a previous update was performed in May 2009. SELECTION CRITERIA: We included all controlled trials that randomly assigned participants to pulse oximetry or no pulse oximetry during...

  18. Neurostimulation using subnanosecond electric pulses

    Science.gov (United States)

    Xiao, Shu; Pakhomov, Andrei; Guo, Fei; Polisetty, Swetha; Schoenbach, Karl H.

    2013-02-01

    We have for the first time recorded action potentials in rat hippocampus neurons when they were stimulated by subnanosecond electric pulses. The preliminary results show that applying a series of pulses allowed the accumulation of depolarization before activating the voltage gated channels. The depolarization only occurred when the electric pulses were applied. It is unclear whether the depolarization is caused by the charge accumulation across the membrane or the cation influx due to the membrane permeabilization. We have also conducted an electromagnetic simulation of delivering subnanosecond pulses to tissues using an impulse radiating antenna. The results show that the pulses can be confined in the deep region in the brain but the amplitude is reduced significantly due to the attenuation of the tissues. A partially lossy dielectric lens may be used to reverse the decreasing trend of the electric field.

  19. Pre-earthquake Magnetic Pulses

    CERN Document Server

    Scoville, John; Freund, Friedemann

    2014-01-01

    A semiconductor model of rocks is shown to describe unipolar magnetic pulses, a phenomenon that has been observed prior to earthquakes. These pulses are observable because their extremely long wavelength allows them to pass through the Earth's crust. Interestingly, the source of these pulses may be triangulated to pinpoint locations where stress is building deep within the crust. We couple a semiconductor drift-diffusion model to a magnetic field in order to describe the electromagnetic effects associated with electrical currents flowing within rocks. The resulting system of equations is solved numerically and it is seen that a volume of rock may act as a diode that produces transient currents when it switches bias. These unidirectional currents are expected to produce transient unipolar magnetic pulses similar in form, amplitude, and duration to those observed before earthquakes, and this suggests that the pulses could be the result of geophysical semiconductor processes.

  20. Effective Instructional Management: Perceptions and Recommendations from High School Administrators

    Science.gov (United States)

    Knechtel, Troy

    2010-01-01

    The two overarching research questions of this study are: What are the perceptions of high school administrators regarding the effectiveness of their current approach to instructional management? What recommendations do high school administrators have for effective strategies for instructional management? To answer these questions, a qualitative…

  1. Effective Instructional Management: Perceptions and Recommendations from High School Administrators

    Science.gov (United States)

    Knechtel, Troy

    2010-01-01

    The two overarching research questions of this study are: What are the perceptions of high school administrators regarding the effectiveness of their current approach to instructional management? What recommendations do high school administrators have for effective strategies for instructional management? To answer these questions, a qualitative…

  2. TRANSFERABILITY OF ADMINISTRATIVE REFORMS: NEW PUBLIC MANAGEMENT AS AN EXAMPLE

    OpenAIRE

    KAPUCU, Naim; Kösecik, Muhammet

    2017-01-01

    This article begins with the examination of models of analyzing the process of policy transfer, lesson drawing and policy streams with regard to initiating and directing factors and dynamics of the process. The paper continues with the assessment of administrative reform transferring by evaluating the necessity, major themes and transferability of administrative reform. Strategies for successful administrative reform transferring are emphasized. Special reference is given to New Public Manage...

  3. Bedload pulses in a hydropower affected alpine gravel bed river

    Science.gov (United States)

    Aigner, Johann; Kreisler, Andrea; Rindler, Rolf; Hauer, Christoph; Habersack, Helmut

    2017-08-01

    This study investigated the sediment resupply and transport dynamics at the Upper Drau River upstream of Lienz (Eastern Tyrol, Austria). Due to a hydropower plant, a 24 km long river reach of this alpine gravel bed river is under residual flow conditions, although sediment is still resupplied into the reach through many active torrents and tributaries. As a result, sediment deposition in the residual flow reach intensified, hence increasing maintenance efforts to stabilize this river section and ensure flood protection. In combination with a new sediment management program, a continuous bedload monitoring system was installed 2 km downstream of the residual reach in 2001 to support the development of adapted sediment management strategies. The surrogate bedload monitoring system consists of 16 impact plate geophones, installed over a 17 m wide cross section. The unprecedented 15-year dataset of high-resolution bedload intensity revealed a complex process of gravel storage and intermittent resupply from the residual reach, allowing the authors a detailed analysis of frequently occurring bedload pulses. These transport features are triggered by increased discharges during floods in the residual reach and created pronounced anticlockwise bedload hysteresis or, with a temporal shift to the event peak, caused distinct shifts in the bedload activity downstream. Bedload pulses produce very high bedload fluxes while in transit, tend to increase bedload flux in the post-event phase, and can alter and reduce the upstream sediment storage leading to a lowering of bedload availability for future pulses. The observed time lags between main discharge events and the arrival of the macro-pulses are correlated with mean water discharge during pulse propagation, thus enabling a prediction of the pulse arrival at the monitoring station solely based on the hydrograph. In combination with the hydrological setup of the reach, the observed bedload pulse time lags allowed an estimation of

  4. ECCM schemes in netted radar system based on temporal pulse diversity

    Institute of Scientific and Technical Information of China (English)

    Ahmed Abdalla; Zhao Yuan; Bin Tang

    2016-01-01

    For a netted radar system to counteract the deception electronic countermeasure (ECM) signals, an effective electronic counter countermeasure (ECCM) approach is proposed. The pro-posed approach is realized based on the new signaling strategy for the temporal pulse diversity, which makes use of transmitting pulses at each pulse repetition interval (PRI) with specific trans-mission pulse block, and then fol owing proper processing and information fusion. The existence of the deceptive ECM signal is confirmed by one station, while the other stations in the netted radar with same parameters applied the pulse diversity skil ful y. Meanwhile, this method ensured that, pulse diversity can be ap-plied in netted radar. The performance assessment shows that the proposed solutions are effective in presence of ECM signals. This algorithm has been demonstrated by simulations. The presented simulation results are in excel ent consensus with theoretical pre-dictions.

  5. Behavioral Public Administration : Combining Insights from Public Administration and Psychology

    OpenAIRE

    Grimmelikhuijsen, S.G.; Jilke, Sebastian; Leth Olsen, Asmus; Tummers, L.G.

    2016-01-01

    We propose behavioral public administration as a designated subfield in public administration which explicitly deals with the integration of theories and methods from psychology into the study of public administration. We discuss how scholars in public administration currently draw on both methodological and theoretical innovations in psychology and point to research questions in public administration which could benefit from further integration. Behavioral public administration cannot, and s...

  6. Behavioral Public Administration: Combining Insights from Public Administration and Psychology

    OpenAIRE

    2015-01-01

    We propose behavioral public administration as a designated subfield in public administration which explicitly deals with the integration of theories and methods from psychology into the study of public administration. We discuss how scholars in public administration currently draw on both methodological and theoretical innovations in psychology and point to research questions in public administration which could benefit from further integration. Behavioral public administration cannot, and s...

  7. Pulse shaping using a spatial light modulator

    CSIR Research Space (South Africa)

    Botha, N

    2009-07-01

    Full Text Available Femtosecond pulse shaping can be done by different kinds of pulse shapers, such as liquid crystal spatial light modulators (LC SLM), acousto optic modulators (AOM) and deformable and movable mirrors. A few applications where pulse shaping...

  8. Pulse source requirements for OTDM systems

    DEFF Research Database (Denmark)

    Clausen, Anders; Poulsen, Henrik Nørskov; Oxenløwe, Leif Katsuo

    2003-01-01

    A simulation model for investigating the impact of incoherent crosstalk due to pulse tail overlapping is proposed. Requirements to pulse width and pulse tail extinction ratio introducing a maximum of 1 dB penalty is extracted....

  9. Practical JIRA Administration

    CERN Document Server

    Doar, Matthew

    2011-01-01

    If you're familiar with JIRA for issue tracking, bug tracking, and other uses, you know it can sometimes be tricky to set up and manage. In this concise book, software toolsmith Matt Doar clarifies some of the more confusing aspects by answering difficult and frequently asked questions about JIRA administration. Practical JIRA Administration shows you how JIRA is intended to be used, making it an ideal supplement to the extensive documentation already available. The book's chapters are loosely connected, so you can go straight to the information that best serves your needs. Understand the di

  10. Computer hardware fault administration

    Science.gov (United States)

    Archer, Charles J.; Megerian, Mark G.; Ratterman, Joseph D.; Smith, Brian E.

    2010-09-14

    Computer hardware fault administration carried out in a parallel computer, where the parallel computer includes a plurality of compute nodes. The compute nodes are coupled for data communications by at least two independent data communications networks, where each data communications network includes data communications links connected to the compute nodes. Typical embodiments carry out hardware fault administration by identifying a location of a defective link in the first data communications network of the parallel computer and routing communications data around the defective link through the second data communications network of the parallel computer.

  11. Land Administration Systems

    DEFF Research Database (Denmark)

    Enemark, Stig

    2014-01-01

    are the rights inherent to all human beings without discrimination. The “constitution” of human rights is the Universal Declaration of Human Rights (UN, 1948) stating the universal rights of human beings based on the principle of respect for the individual – rights that can be enjoyed by everyone simple because...... and that every country and jurisdiction needs to ensure that efficient and effective land administration mechanisms are in place to pursue this interaction. Land administration systems should embed a human rights perspective when managing rights, restrictions and responsibilities in land. This, in turn, imposes...

  12. Pro Python System Administration

    CERN Document Server

    Sileika, R

    2010-01-01

    As time goes on, system administrators are presented with increasingly complicated challenges. In the early days, a team of engineers might have had to look after one or two systems. These days, one engineer can administer hundreds or thousands of systems. System administrators are gradually replacing their tools with more advanced and flexible ones. One of the choices is Python. Structurally, Python is a modern, high-level language with a very clean syntax. Python comes with many built-in libraries that can make automation tasks easier. It also has extensive set of third-party libraries and a

  13. Linux System Administration

    CERN Document Server

    Adelstein, Tom

    2007-01-01

    If you're an experienced system administrator looking to acquire Linux skills, or a seasoned Linux user facing a new challenge, Linux System Administration offers practical knowledge for managing a complete range of Linux systems and servers. The book summarizes the steps you need to build everything from standalone SOHO hubs, web servers, and LAN servers to load-balanced clusters and servers consolidated through virtualization. Along the way, you'll learn about all of the tools you need to set up and maintain these working environments. Linux is now a standard corporate platform with user

  14. 75 FR 4631 - Open Season for Membership to the Electronic Tax Administration Advisory Committee (ETAAC)

    Science.gov (United States)

    2010-01-28

    ... options and best practices), (8) system integrators (technology providers), (9) academic (marketing, sales... implementation of the Internal Revenue Service (IRS) strategy for electronic tax administration. The ETAAC...

  15. Performance Analysis of the Romanian Administration

    Directory of Open Access Journals (Sweden)

    Marius Constantin PROFIROIU

    2013-10-01

    Full Text Available The performance of public administration is one of the top priorities of the national governments worldwide, not only for Romania. The role of a performing management system at the level of public administration is to ensure a high quality and efficiency of the adopted policies and strategies, of the provided public services and of the administrative act itself, and to guarantee the advantage of a competitive and efficient administration both in relation to its own citizens, and in competition with other cities and countries throughout Europe and all around the world. Following these considerations, and based upon an empirical research conducted with the aid of a survey regarding ‘The analysis of the performance level of the Romanian public administration’ the article aims to (1 identify modern management tools that determine and influence the performance of Romanian public institutions, (2 analyze the effects of using project management as organizational capacity development instruments by public administration in Romania, and (3 determine the influence and effects of the external factors on the performance and development of Romanian public administration.

  16. Bomb pulse biology

    Energy Technology Data Exchange (ETDEWEB)

    Falso, Miranda J. Sarachine [Center for Accelerator Mass Spectrometry, Mail Stop L-397, Lawrence Livermore National Laboratory, P.O. Box 808, Livermore, CA 94551 (United States); Buchholz, Bruce A., E-mail: buchholz2@llnl.gov [Center for Accelerator Mass Spectrometry, Mail Stop L-397, Lawrence Livermore National Laboratory, P.O. Box 808, Livermore, CA 94551 (United States)

    2013-01-15

    The past decade has seen an explosion in use of the {sup 14}C bomb pulse to do fundamental cell biology. Studies in the 1960s used decay counting to measure tissue turnover when the atmospheric {sup 14}C/C concentration was changing rapidly. Today bulk tissue measurements are of marginal interest since most of the carbon in the tissue resides in proteins, lipids and carbohydrates that turn over rapidly. Specific cell types with specialized functions are the focus of cell turnover investigations. Tissue samples need to be fresh or frozen. Fixed or preserved samples contain petroleum-derived carbon that has not been successfully removed. Cell or nuclear surface markers are used to sort specific cell types, typically by fluorescence-activated cell sorting (FACS). Specific biomolecules need to be isolated with high purity and accelerator mass spectrometry (AMS) measurements must accommodate samples that generally contain less than 40 {mu}g of carbon. Furthermore, all separations must not add carbon to the sample. Independent means such as UV absorbance must be used to confirm molecule purity. Approaches for separating specific proteins and DNA and combating contamination of undesired molecules are described.

  17. Pulsed electron beam precharger

    Energy Technology Data Exchange (ETDEWEB)

    Finney, W.C. (ed.); Shelton, W.N.

    1990-01-01

    Electrostatic collection of a high resistivity aerosol using the Electron Beam Precipitator (EBP) collecting section was demonstrated during this reporting period (Quarter Five). Collection efficiency experiments were designed to confirm and extend some of the work performed under the previous contract. The reason for doing this was to attempt to improve upon the collection efficiency of the precipitator alone when testing with a very high resistivity, moderate-to-high concentration dust load. From the collector shakedown runs, a set of suitable operational parameters were determined for the downstream electrostatic collecting sections of the Electron Beam Precipitator wind tunnel. These parameters, along with those for the MINACC electron beam, will generally be held constant while the numerous precharging parameters are varied to produce an optimum particle charge. The electrostatic collector experiments were part of a larger, comprehensive investigation on electron beam precharging of high resistivity aerosol particles performed during the period covered by Quarters Five, Six, and Seven. This body of work used the same experimental apparatus and procedures and the experimental run period lasted nearly continuously for six months. A summary of the Quarter Five work is presented in the following paragraphs. Section II-A of TPR 5 contains a report on the continuing effort which was expended on the modification and upgrade of the pulsed power supply and the monitoring systems prior to the initiation of the electron beam precharging experimental work.

  18. Magnetic Alignment of Pulsed Solenoids Using the Pulsed Wire Method

    Energy Technology Data Exchange (ETDEWEB)

    Arbelaez, D.; Madur, A.; Lipton, T.M.; Waldron, W.L.; Kwan, J.W.

    2011-04-01

    A unique application of the pulsed-wire measurement method has been implemented for alignment of 2.5 T pulsed solenoid magnets. The magnetic axis measurement has been shown to have a resolution of better than 25 {micro}m. The accuracy of the technique allows for the identification of inherent field errors due to, for example, the winding layer transitions and the current leads. The alignment system is developed for the induction accelerator NDCX-II under construction at LBNL, an upgraded Neutralized Drift Compression experiment for research on warm dense matter and heavy ion fusion. Precise alignment is essential for NDCX-II, since the ion beam has a large energy spread associated with the rapid pulse compression such that misalignments lead to corkscrew deformation of the beam and reduced intensity at focus. The ability to align the magnetic axis of the pulsed solenoids to within 100 pm of the induction cell axis has been demonstrated.

  19. Causality effects on accelerating light pulses

    National Research Council Canada - National Science Library

    Kaminer, Ido; Lumer, Yaakov; Segev, Mordechai; Christodoulides, Demetrios N

    2011-01-01

    .... We explore the effects of causality, and find that, whereas decelerating pulses can asymptotically reach zero group velocity, pulses that accelerate towards infinite group velocity inevitably break...

  20. Pulsed ultrasonic stir welding method

    Science.gov (United States)

    Ding, R. Jeffrey (Inventor)

    2013-01-01

    A method of performing ultrasonic stir welding uses a welding head assembly to include a plate and a rod passing through the plate. The rod is rotatable about a longitudinal axis thereof. In the method, the rod is rotated about its longitudinal axis during a welding operation. During the welding operation, a series of on-off ultrasonic pulses are applied to the rod such that they propagate parallel to the rod's longitudinal axis. At least a pulse rate associated with the on-off ultrasonic pulses is controlled.

  1. Hyper dispersion pulse compressor for chirped pulse amplification systems

    Science.gov (United States)

    Barty, Christopher P. J.

    2011-11-29

    A grating pulse compressor configuration is introduced for increasing the optical dispersion for a given footprint and to make practical the application for chirped pulse amplification (CPA) to quasi-narrow bandwidth materials, such as Nd:YAG. The grating configurations often use cascaded pairs of gratings to increase angular dispersion an order of magnitude or more. Increased angular dispersion allows for decreased grating separation and a smaller compressor footprint.

  2. Telecommunications administration standard

    Energy Technology Data Exchange (ETDEWEB)

    Gustwiller, K.D. [GTE Customer Networks, Albuquerque, NM (United States)

    1996-05-01

    The administration of telecommunications is critical to proper maintenance and operation. The intent is to be able to properly support telecommunications for the distribution of all information within a building/campus. This standard will provide a uniform administration scheme that is independent of applications, and will establish guidelines for owners, installers, designers and contractors. This standard will accommodate existing building wiring, new building wiring and outside plant wiring. Existing buildings may not readily adapt to all applications of this standard, but the requirement for telecommunications administration is applicable to all buildings. Administration of the telecommunications infrastructure includes documentation (labels, records, drawings, reports, and work orders) of cables, termination hardware, patching and cross-connect facilities, telecommunications rooms, and other telecommunications spaces (conduits, grounding, and cable pathways are documented by Facilities Engineering). The investment in properly documenting telecommunications is a worthwhile effort. It is necessary to adhere to these standards to ensure quality and efficiency for the operation and maintenance of the telecommunications infrastructure for Sandia National Laboratories.

  3. Educational Administration's Weber.

    Science.gov (United States)

    Gronn, Peter

    1994-01-01

    Discusses Max Weber's importance in Greenfield's work, particularly in Greenfield and Ribbins'"Greenfield on Educational Administration" (1993). In concentrating on human actors' subjective understanding, Greenfield was a faithful Weberian. However, he deviated from Weber by disavowing structural explanations of social and organizational…

  4. Refinement for Administrative Policies

    NARCIS (Netherlands)

    Dekker, M.A.C.; Etalle, Sandro; Jonker, Willem; Jonker, W.; Petkovic, M.

    Flexibility of management is an important requisite for access control systems as it allows users to adapt the access control system in accordance with practical requirements. This paper builds on earlier work where we defined administrative policies for a general class of RBAC models. We present a

  5. Refinement for administrative policies

    NARCIS (Netherlands)

    Dekker, M.A.C.; Etalle, S.

    2007-01-01

    Flexibility of management is an important requisite for access control systems as it allows users to adapt the access control system in accordance with practical requirements. This paper builds on earlier work where we defined administrative policies for a general class of RBAC models. We present a

  6. Refinement for Administrative Policies

    NARCIS (Netherlands)

    Dekker, M.A.C.; Etalle, Sandro

    2007-01-01

    Flexibility of management is an important requisite for access control systems as it allows users to adapt the access control system in accordance with practical requirements. This paper builds on earlier work where we defined administrative policies for a general class of RBAC models. We present a

  7. Educator Effectiveness Administrative Manual

    Science.gov (United States)

    Pennsylvania Department of Education, 2014

    2014-01-01

    The goal of this manual is to provide guidance in the evaluation of educators, highlight critical components of effectiveness training, and offer opportunities for professional growth. The term "educator" includes teachers, all professional and temporary professional employees, education specialists, and school administrators/principals.…

  8. Discretionary Grants Administration Manual.

    Science.gov (United States)

    Office of Human Development Services (DHHS), Washington, DC.

    This manual sets forth applicable administrative policies and procedures to recipients of discretionary project grants or cooperative agreements awarded by program offices in the Office of Human Development Services (HDS). It is intended to serve as a basic reference for project directors and business officers of recipient organizations who are…

  9. Administrators Confront Student "Sexting"

    Science.gov (United States)

    Manzo, Kathleen Kennedy

    2009-01-01

    Cellphone-savvy students have created instructional and disciplinary challenges for educators for years. But the recent emergence of "sexting" by adolescents over their mobile phones caught many school administrators off guard, and the practice is prompting efforts around the country to craft policy responses. Students' sharing of nude or…

  10. Ethics in Public Administration

    Directory of Open Access Journals (Sweden)

    MSc. Arjeta Hallunovi

    2014-06-01

    Full Text Available The goal of this study is to deal with some ethical causes in the public administration, that aim the avoidance of negative phenomenon’s as theft, corruption, etc. In this direction, the debates about ethics are becoming more and more a global tendency, as an implement through which would be found the way to get out of the crisis. The success in the reforms of the public administrations in major part depends, on the public functionaries and their willingness to make fundamental changes in the way they work. In this direction, the State should strengthen and modernize the public service, should realize an employment system, which should reflect more the merits on its service. For this reason, the government’s attempts should be concentrated on the construction of a positive image for the state and its administration as professional objective, which is oriented to the services. Being aware for the practical restrictions of this study, we firstly chose to concentrate on the local public administrations ethics. The study will be focused on the practical comparative analysis of the city of Shkodra and Durres by the realization of a questionnaire by each of these municipalities and the Agency of Legalization and Urbanization of Informal Zones (ALUIZNI in Shkodra.

  11. Urban School Administration.

    Science.gov (United States)

    McKelvey, Troy V., Ed.; Swanson, Austin D., Ed.

    This document contains 12 papers presented at an institute for urban school administrators designed to deal with the contemporary urban educational problems incident to school desegregation, social integration, and the equality of educational opportunity. The authors of the papers relate recent research findings to practical field experience, and…

  12. IVA: Improving Vocational Administration.

    Science.gov (United States)

    EPD Consortium D, Richardson, TX.

    These six instructional units are intended to provide instructors of vocational education administration with a systematic package of materials for their programs of preservice and/or inservice instruction and to provide materials which could be reproduced for learner use. These units cover the following subject matter: (1) federal legislation…

  13. Renaissance Administrator, Spring 1998.

    Science.gov (United States)

    Dowdy, June P., Ed.

    1998-01-01

    This spring 1998 issue of Renaissance Administrator features the following articles: (1) "Servant Leadership and Higher Education--What is Leadership?" (Richard E. Hasselbach); (2) "Teaching Writing in the 90's--Carnivorous Printers and Dying Grandmothers" (Helen Ruggieri); (3) Assignment--Journal Writing" (Lynn Muscato); and (4) "A Business…

  14. A Treatise on Administration.

    Science.gov (United States)

    Moore, Thomas R.

    1988-01-01

    Expands Henri Fayol's definition of the administrative process to include a humanistic approach involving planning, organizing, implementing, controlling, evaluating, and satisfying functions. This empirical definition differs from some theoretical approaches by looking beyond resource consumption to consider ecological effects on the environment…

  15. IVA: Improving Vocational Administration.

    Science.gov (United States)

    EPD Consortium D, Richardson, TX.

    These six instructional units are intended to provide instructors of vocational education administration with a systematic package of materials for their programs of preservice and/or inservice instruction and to provide materials which could be reproduced for learner use. These units cover the following subject matter: (1) federal legislation…

  16. ADMINISTRATIVE RULEMAKING IN ETHIOPIA:

    African Journals Online (AJOL)

    MLR

    or policy or describing the organization, procedure, or practice requirements of an agency … ... Draft Proclamation) prepared by the Justice and Legal System Research ... organ of the government as in the cases of contract law, criminal law, family ..... public is an important administrative procedure they all share in common.

  17. Enterprise Mac administrators guide

    CERN Document Server

    Smith, William

    2015-01-01

    IT departments everywhere will be integrating Macs and Mac OS X into their IT infrastructure and this book will tell them how to do it. It will serve as an authoritative, useful and frequently referenced book on Mac OS X administration.

  18. Refinement for Administrative Policies

    NARCIS (Netherlands)

    Dekker, M.A.C.; Etalle, S.

    2007-01-01

    Flexibility of management is an important requisite for access control systems as it allows users to adapt the access control system in accordance with practical requirements. This paper builds on earlier work where we defined administrative policies for a general class of RBAC models. We present a

  19. Refinement for administrative policies

    NARCIS (Netherlands)

    Dekker, M.A.C.; Etalle, S.

    2007-01-01

    Flexibility of management is an important requisite for access control systems as it allows users to adapt the access control system in accordance with practical requirements. This paper builds on earlier work where we defined administrative policies for a general class of RBAC models. We present a

  20. Strategie podniku

    OpenAIRE

    Podhradská, Martina

    2013-01-01

    This paper deals with a process of strategy definition of Starkl -- zahradník s.r.o. company. The main target of this diploma thesis is to elaborate external and internal analysis and to assess present strategy, alternatively to suggest a new strategy reflecting competitive environment.

  1. Ultrashort Laser Pulse Heating of Nanoparticles: Comparison of Theoretical Approaches

    Directory of Open Access Journals (Sweden)

    Renat R. Letfullin

    2008-01-01

    Full Text Available The interaction between nanoparticles and ultrashort laser pulses holds great interest in laser nanomedicine, introducing such possibilities as selective cell targeting to create highly localized cell damage. Two models are studied to describe the laser pulse interaction with nanoparticles in the femtosecond, picosecond, and nanosecond regimes. The first is a two-temperature model using two coupled diffusion equations: one describing the heat conduction of electrons, and the other that of the lattice. The second model is a one-temperature model utilizing a heat diffusion equation for the phonon subsystem and applying a uniform heating approximation throughout the particle volume. A comparison of the two modeling strategies shows that the two-temperature model gives a good approximation for the femtosecond mode, but fails to accurately describe the laser heating for longer pulses. On the contrary, the simpler one-temperature model provides an adequate description of the laser heating of nanoparticles in the femtosecond, picosecond, and nanosecond modes.

  2. Complex pulsing schemes for high frame rate imaging

    DEFF Research Database (Denmark)

    Misaridis, Thanassis; Fink, Mathias; Jensen, Jørgen Arendt

    2002-01-01

    High frame rate ultrasound imaging can be achieved by simultaneous transmission of multiple focused beams along different directions. However, image quality degrades by the interference among beams. An alternative approach is to transmit spherical waves of a basic short pulse with frequency coding...... with linear frequency modulation along the transducer elements, that cover the 70% fractional bandwidth of the 7 MHz transducer. The resulted images (after beamforming and matched filtering) show an axial resolution at the same order as in conventional pulse excitation and axial sidelobes down to -45 d......B. With the proposed imaging strategy of pulse train excitation, a whole image can be formed with only two emissions, making it possible to obtain high quality images at a frame rate of 20 to 25 times higher than that of conventional phased array imaging...

  3. Administrative burdens and dairy industry competitiveness

    OpenAIRE

    Bremmers, H.J.; Poppe, K.J.; Wijnands, J.H.M.; Meulen, van der, GG George

    2008-01-01

    The goal of this paper is to assess the effect of regulatory burdens in the European dairy industry on its competitiveness. A theoretical foundation is provided by transaction cost economics and total quality management insights. The effects of legislation on administrative requirements and competitiveness are supposed to be mediated by impacts on innovativeness, company strategy, food safety system availability, as well as the available information & communication capabilities. We will conne...

  4. Pulse-to-pulse Diagnostics at High Reprate

    Science.gov (United States)

    Green, Bertram; Kovalev, Sergey; Golz, Torsten; Stojanovich, Nikola; Fisher, Alan; Kampfrath, Tobias; Gensch, Michael

    2016-03-01

    Femtosecond level diagnostic and control of sub-picosecond electron bunches is an important topic in modern accelerator research. At the same time new linear electron accelerators based on quasi-CW SRF technology will be the drivers of many future 4th Generation lightsources such as X-ray free electron lasers. A high duty cycle, high stability and online pulse to pulse diagnostic at these new accelerators are crucial ingredients to the success of these large scale facilities. A novel THz based online monitor concept is presented that has the potential to give access to pulse to pulse information on bunch form, arrival time and energy at high repetition rate and down to sub pC charges. We furthermore show experimentally that pulse to pulse arrival time measurements can be used to perform pump-probe experiments with a temporal resolution in the few-fs regime and an exceptional dynamic range. Our scheme has been tested at the superradiant test facility TELBE, but can be readily transferred to other SRF accelerator driven photon sources, such as X-FELs.

  5. Pulsed light and pulsed electric field for foods and eggs.

    Science.gov (United States)

    Dunn, J

    1996-09-01

    Two new technologies for use in the food industry are described. The first method discussed uses intense pulse of light. This pulsed light (PureBright) process uses short duration flashes of broad spectrum "white" light to kill all exposed microorganisms, including vegetative bacteria, microbial and fungal spores, viruses, and protozoan oocysts. Each pulse, or flash, of light lasts only a few hundred millionths of a second (i.e., a few hundred microseconds). The intensity of each flash of light is about 20,000 times the intensity of sunlight at the earth's surface. The flashes are typically applied at a rate of about one to tens of flashes per second. For most applications, a few flashes applied in a fraction of a second provide an effective treatment. High microbial kill can be achieved, for example, on the surfaces of packaging materials, on packaging and processing equipment, foods, and medical devices as well as on many other surfaces. In addition, some bulk materials such as water and air that allow penetration of the light can be sterilized. The results of tests to measure the effects of pulsed light on Salmonella enteritiditis on eggs are presented. The second method discussed uses multiple, short duration, high intensity electric field pulses to kill vegetative microorganisms in pumpable products. This pulsed electric field (or CoolPure) process can be applied at modest temperatures at which no appreciable thermal damage occurs and the original taste, color, texture, and functionality of products can be retained.

  6. Treatment of Persistent Facial Postinflammatory Hyperpigmentation With Novel Pulse-in-Pulse Mode Intense Pulsed Light.

    Science.gov (United States)

    Park, Ji-Hye; Kim, Jung-In; Kim, Won-Serk

    2016-02-01

    Postinflammatory hyperpigmentation (PIH) is an acquired hypermelanosis induced by various causes including inflammatory dermatoses, injury, or cosmetic procedures, such as lasers or chemical peels, and it tends to affect dark-skinned people with greater frequency and severity. There are a variety of treatment options for PIH, including topical agents, chemical peels, laser, and light therapy. However, the results are not up to expectation. The purpose of this study was to examine the clinical efficacy and safety of novel pulse-in-pulse mode intense pulsed light (IPL) for the treatment of persistent facial PIH in Korean patients. Twenty-five Korean female patients (Fitzpatrick skin types III-V) with persistent facial PIH were enrolled in the study. The patients were treated with novel pulse-in-pulse mode IPL for 4 sessions at 1-week interval and 4 sessions at 2-week intervals. Treatment efficacy and patient satisfaction were evaluated using photographs and questionnaires. After 2 months of all treatments, 23 patients (92%) had more than 50% improvement and 22 patients (88%) were satisfied with the treatments. No adverse effects or aggravations were reported. The pulse-in-pulse mode IPL treatment is effective and safe for persistent facial PIH in dark-skinned patients.

  7. Intense pulsed neutron source

    Science.gov (United States)

    The IPNS Progress Report 10th Anniversary Edition is being published in recognition of the first ten years of successful IPNS operation. To emphasize the significance of this milestone, we wanted this report to stand apart from the previous IPNS Progress Reports, and the best way to do this, we thought, was to make the design and organization of the report significantly different. In their articles, authors were asked to emphasize not only advances made since IPNS began operating but also the groundwork that was laid at its predecessor facilities - Argonne's ZING-P and ZING-P' prototype pulsed neutron sources and CP-5 reactor. Each article stands as a separate chapter in the report, since each represents a particular instrument or class of instruments, system, technique, or area of research. In some cases, contributions were similar to review articles in scientific journals, complete with extensive lists of references. Ten-year cumulative lists of members of IPNS committees and of scientists who have visited or done experiments at IPNS were assembled. A list of published and 'in press' articles in journals, books, and conference proceedings, resulting from work done at IPNS during the past ten years, was compiled. And archival photographs of people and activities during the ten-year history of IPNS were located and were used liberally throughout the report. The titles of the chapters in this report are: accelerator; computer; radiation effects; powder; stress; single crystal; superconductivity; amorphous; small angle; reflection; quasielastic; inelastic; inelastic magnetic; deep inelastic; user program; the future; and publications.

  8. Next generation Chirped Pulse Amplification

    Energy Technology Data Exchange (ETDEWEB)

    Nees, J.; Biswal, S.; Mourou, G. [Univ. Michigan, Center for Ultrafast Optical Science, Ann Arbor, MI (United States); Nishimura, Akihiko; Takuma, Hiroshi

    1998-03-01

    The limiting factors of Chirped Pulse Amplification (CPA) are discussed and experimental results of CPA in Yb:glass regenerative amplifier are given. Scaling of Yb:glass to the petawatt level is briefly discussed. (author)

  9. Rapidly pulsed helium droplet source

    Energy Technology Data Exchange (ETDEWEB)

    Pentlehner, Dominik; Riechers, Ricarda; Dick, Bernhard; Slenczka, Alkwin [Institute for Physical and Theoretical Chemistry, University of Regensburg, 93053 Regensburg (Germany); Even, Uzi; Lavie, Nachum; Brown, Raviv; Luria, Kfir [Sackler Faculty of Exact Sciences, School of Chemistry, Tel Aviv University, Ramat Aviv, 69978 Tel Aviv (Israel)

    2009-04-15

    A pulsed valve connected to a closed-cycle cryostat was optimized for producing helium droplets. The pulsed droplet beam appeared with a bimodal size distribution. The leading part of the pulse consists of droplets suitable for doping with molecules. The average size of this part can be varied between 10{sup 4} and 10{sup 6} helium atoms, and the width of the distribution is smaller as compared to a continuous-flow droplet source. The system has been tested in a single pulse mode and at repetition rates of up to 500 Hz with almost constant intensity. The droplet density was found to be increased by more than an order of magnitude as compared to a continuous-flow droplet source.

  10. Low-noise pulse conditioner

    Science.gov (United States)

    Bird, D.A.

    1981-06-16

    A low-noise pulse conditioner is provided for driving electronic digital processing circuitry directly from differentially induced input pulses. The circuit uses a unique differential-to-peak detector circuit to generate a dynamic reference signal proportional to the input peak voltage. The input pulses are compared with the reference signal in an input network which operates in full differential mode with only a passive input filter. This reduces the introduction of circuit-induced noise, or jitter, generated in ground referenced input elements normally used in pulse conditioning circuits, especially speed transducer processing circuits. This circuit may be used for conditioning the sensor signal from the Fidler coil in a gas centrifuge for separation of isotopic gaseous mixtures.

  11. Pulse tube refrigerator; Parusukan reitoki

    Energy Technology Data Exchange (ETDEWEB)

    Hozumi, Yoshikazu [University of Tsukuba, Tsukuba (Japan); Shiraishi, Masao [Hiroshima University, Hiroshima (Japan)

    1999-06-05

    In the cryogenic field, high temperature superconductivity and research and development of the peripheral technology are popular. Refrigerating machine development of the very low temperature is also one of the results. Research and development are mainly advanced as a refrigerating machine of the center for the aerospace plane installation. There is special and small very low temperature refrigerating machine called 'the pulse tube refrigerating machine' of which the practical application is also recently being attempted for the semiconductor cooling using high temperature superconductivity. At present, the basic research of elucidation of refrigeration phenomenon of pulse tube refrigerating machine and development of high-performance pulse tube refrigerating machine is carried out by experiment in the Ministry of International Trade and Industry Mechanical Engineering Lab., Agency of Industrial Sci. and Technology and numerical simulation in Chiyoda Corp. In this report, the pulse tube refrigerating machine is introduced, and the application in the chemical engineering field is considered. (NEDO)

  12. 76 FR 51375 - Dialogues in Diversifying Clinical Trials: Successful Strategies for Engaging Women and...

    Science.gov (United States)

    2011-08-18

    ... HUMAN SERVICES Food and Drug Administration Dialogues in Diversifying Clinical Trials: Successful Strategies for Engaging Women and Minorities in Clinical Trials AGENCY: Food and Drug Administration, HHS... Diversifying Clinical Trials: Successful Strategies for Engaging Women and Minorities in Clinical Trials....

  13. Pulse versus continuous peracetic acid applications: effects on Rainbow trout performance, biofilm formation and water quality

    Science.gov (United States)

    Peracetic acid (PAA) products are being introduced to aquaculture as sustainable disinfectants. Two strategies are used to apply PAA: short term high dose (1-2 mg L-1 PAA) periodic pulse applications or continuous low dose (< 0.2 mg L-1 PAA) applications. In the present study, these strategies and a...

  14. Pulsed laser manipulation of an optically trapped bead: Averaging thermal noise and measuring the pulsed force amplitude

    DEFF Research Database (Denmark)

    Lindballe, Thue Bjerring; Kristensen, Martin V. G.; Berg-Sørensen, Kirstine

    2013-01-01

    An experimental strategy for post-eliminating thermal noise on position measurements of optically trapped particles is presented. Using a nanosecond pulsed laser, synchronized to the detection system, to exert a periodic driving force on an optically trapped 10 polystyrene bead, the laser pulse......-bead interaction is repeated hundreds of times. Traces with the bead position following the prompt displacement from equilibrium, induced by each laser pulse, are averaged and reveal the underlying deterministic motion of the bead, which is not visible in a single trace due to thermal noise. The motion of the bead...... is analyzed from the direct time-dependent position measurements and from the power spectrum. The results show that the bead is on average displaced 208 nm from the trap center and exposed to a force amplitude of 71 nanoNewton, more than five orders of magnitude larger than the trapping forces. Our...

  15. Behavioral Public Administration: Combining Insights from Public Administration and Psychology

    DEFF Research Database (Denmark)

    Grimmelikhuijsen, Stephan; Jilke, Sebastian; Olsen, Asmus Leth

    2015-01-01

    We propose behavioral public administration as a designated subfield in public administration which explicitly deals with the integration of theories and methods from psychology into the study of public administration. We discuss how scholars in public administration currently draw on both......, behavioral public administration represents a two-way street in which public administration scholars use theories and methods from psychology, and psychologists, in turn, learn from our setting of political-administrative contexts to refine their theories and methods. Finally, we propose four principals...... methodological and theoretical innovations in psychology and point to research questions in public administration which could benefit from further integration. Behavioral public administration cannot, and should not, replace ‘conventional’ public administration, but it is complementary to it. Importantly...

  16. Pulsed ultrasonic stir welding system

    Science.gov (United States)

    Ding, R. Jeffrey (Inventor)

    2013-01-01

    An ultrasonic stir welding system includes a welding head assembly having a plate and a rod passing through the plate. The rod is rotatable about a longitudinal axis thereof. During a welding operation, ultrasonic pulses are applied to the rod as it rotates about its longitudinal axis. The ultrasonic pulses are applied in such a way that they propagate parallel to the longitudinal axis of the rod.

  17. Optical pulses, lasers, measuring techniques

    CERN Document Server

    Früngel, Frank B A

    1965-01-01

    High Speed Pulse Technology: Volume II: Optical Pulses - Lasers - Measuring Techniques focuses on the theoretical and engineering problems that result from the capacitor discharge technique.This book is organized into three main topics: light flash production from a capacitive energy storage; signal transmission and ranging systems by capacitor discharges and lasers; and impulse measuring technique. This text specifically discusses the air spark under atmospheric conditions, industrial equipment for laser flashing, and claims for light transmitting system. The application of light impulse sign

  18. Pulsed feedback defers cellular differentiation.

    Directory of Open Access Journals (Sweden)

    Joe H Levine

    2012-01-01

    Full Text Available Environmental signals induce diverse cellular differentiation programs. In certain systems, cells defer differentiation for extended time periods after the signal appears, proliferating through multiple rounds of cell division before committing to a new fate. How can cells set a deferral time much longer than the cell cycle? Here we study Bacillus subtilis cells that respond to sudden nutrient limitation with multiple rounds of growth and division before differentiating into spores. A well-characterized genetic circuit controls the concentration and phosphorylation of the master regulator Spo0A, which rises to a critical concentration to initiate sporulation. However, it remains unclear how this circuit enables cells to defer sporulation for multiple cell cycles. Using quantitative time-lapse fluorescence microscopy of Spo0A dynamics in individual cells, we observed pulses of Spo0A phosphorylation at a characteristic cell cycle phase. Pulse amplitudes grew systematically and cell-autonomously over multiple cell cycles leading up to sporulation. This pulse growth required a key positive feedback loop involving the sporulation kinases, without which the deferral of sporulation became ultrasensitive to kinase expression. Thus, deferral is controlled by a pulsed positive feedback loop in which kinase expression is activated by pulses of Spo0A phosphorylation. This pulsed positive feedback architecture provides a more robust mechanism for setting deferral times than constitutive kinase expression. Finally, using mathematical modeling, we show how pulsing and time delays together enable "polyphasic" positive feedback, in which different parts of a feedback loop are active at different times. Polyphasic feedback can enable more accurate tuning of long deferral times. Together, these results suggest that Bacillus subtilis uses a pulsed positive feedback loop to implement a "timer" that operates over timescales much longer than a cell cycle.

  19. Artistic Representation with Pulsed Holography

    Science.gov (United States)

    Ishii, S.

    2013-02-01

    This thesis describes artistic representation through pulsed holography. One of the prevalent practical problems in making holograms is object movement. Any movement of the object or film, including movement caused by acoustic vibration, has the same fatal results. One way of reducing the chance of movement is by ensuring that the exposure is very quick; using a pulsed laser can fulfill this objective. The attractiveness of using pulsed laser is based on the variety of materials or objects that can be recorded (e.g., liquid material or instantaneous scene of a moving object). One of the most interesting points about pulsed holograms is that some reconstructed images present us with completely different views of the real world. For example, the holographic image of liquid material does not appear fluid; it looks like a piece of hard glass that would produce a sharp sound upon tapping. In everyday life, we are unfamiliar with such an instantaneous scene. On the other hand, soft-textured materials such as a feather or wool differ from liquids when observed through holography. Using a pulsed hologram, we can sense the soft touch of the object or material with the help of realistic three-dimensional (3-D) images. The images allow us to realize the sense of touch in a way that resembles touching real objects. I had the opportunity to use a pulsed ruby laser soon after I started to work in the field of holography in 1979. Since then, I have made pulsed holograms of activities, including pouring water, breaking eggs, blowing soap bubbles, and scattering feathers and popcorn. I have also created holographic art with materials and objects, such as silk fiber, fabric, balloons, glass, flowers, and even the human body. Whenever I create art, I like to present the spectator with a new experience in perception. Therefore, I would like to introduce my experimental artwork through those pulsed holograms.

  20. High Voltage Pulse Testing Survey.

    Science.gov (United States)

    1985-10-01

    Cryogenic 23 E. Liquids 26 F. Solids 28 1. Polyethylene 28 2. Cross-Linked Polyethylene ( XLPE ) 29 3. Polyimide and Polyvenylchloride (PVC) 31 VI Benefits 35 A...Strength of XLPE Cables 29 vii * 4" I PROGRAM OBJECTIVES The Pulse Test Survey summarizes government, industry, and technical reports on high voltage pulse...system of silicone oil on a XLPE (cross-linked polyethylene) spacer tends to lower the impulse breakdown by approximately 10 percent. The negative impulse

  1. Millijoule pulse energy picosecond fiber chirped-pulse amplification system

    Institute of Scientific and Technical Information of China (English)

    Zhi Yang; Xiaohong Hu; Yishan Wang; Wei Zhang; Wei Zhao

    2011-01-01

    @@ The efficient generation of a 1.17-mJ laser pul8e with 360 ps duration using an ytterbium (Yb)-doped fiber amplifier chain seeded by a homemade mode-locked fiber laser is demonstrated experimentally.A specially designed figure-of-eight fiber laser acts as the seed source of a chirped-pulse amplification (CPA) system and generates mode-locked pulse8 with hundreds of picosecond widths.Two kinds of large-mode-area (LMA) double-clad Yb-doped fibers are employed to construct the pre-amplifier and main amplifier, All of the adopted instruments help avoid severe nonlinearity in fibers to raise sub-nanosecond pulse energy with acceptable signal-to-noise ratio (SNR).The output spectrum of this fiber-based CPA system shows that amplified spontaneous emission (ASE) is suppressed to better than 30 dB, and the onset of stimulated Raman scattering is excluded.%The efficient generation of a 1.17-mJ laser pulse with 360 ps duration using an ytterbium (Yb)-doped fiber amplifier chain seeded by a homemade mode-locked fiber laser is demonstrated experimentally. A specially designed figure-of-eight fiber laser acts as the seed source of a chirped-pulse amplification (CPA) system and generates mode-locked pulses with hundreds of picosecond widths. Two kinds of large-mode-area (LMA) double-clad Yb-doped fibers are employed to construct the pre-amplifier and main amplifier. All of the adopted instruments help avoid severe nonlinearity in fibers to raise sub-nanosecond pulse energy with acceptable signal-to-noise ratio (SNR). The output spectrum of this fiber-based CPA system shows that amplified spontaneous emission (ASE) is suppressed to better than 30 dB, and the onset of stimulated Raman scattering is excluded.

  2. 119 Rebranding as an Administrative Strategy in Nigeria: The ...

    African Journals Online (AJOL)

    FIRST LADY

    2011-01-18

    Jan 18, 2011 ... relations would be needed to kick-start the process, here lies the rebranding initiative, only time ... Appadorai, A. (2004), The substance of politics, New Delhi, India: ... a press conference to the launch: The Rebranding Nigeria.

  3. School Administrators Strategies for Combating Corruption in Universities in Nigeria

    Science.gov (United States)

    Asiyai, Romina Ifeoma

    2015-01-01

    The purpose of this study was to examine corruption in universities with the aim of finding out the types/forms, causes, effects and measures for combating the menace. Four research questions guided the investigation. The study is a survey research, ex-post facto in nature. A sample of 780 comprising of students, academic staff and administrative…

  4. [Local and citizen participation and representation strategies in Healthcare Administration].

    Science.gov (United States)

    Sancho Serena, Francesc; Grané Alsina, Montserrat; Olivet, Miquel

    2015-11-01

    The public as a whole are the rightful owners and beneficiaries of the public healthcare system in our country. As such, they collaborate in its maintenance and upkeep through payment of taxes. The government is accountable to the public as to how the ever-scarce resources are allocated. When it comes to the area of healthcare, this represents an added factor of complexity and specificity which makes the issue a particularly sensitive one. In the field of healthcare, both the General Health Law and the Law of Catalan Healthcare Code define the actors responsible for the public representation of its citizens. Nevertheless, their inclusion does not necessarily guarantee the perception of participation by its citizens or that of a greater democratic quality. The model must be understood as the intermediary link between a legally regulated framework and the actual debate, which in a globalized world with such an immense volume of information available to citizens and with the current online social networking sites, occurs at the heart of society in general, even though government has no such incorporation channel. The system will need to be developed as new technologies enable this, towards a more direct and more global models for participation. Participation is a flexible concept which, as far as possible, needs to adapt to the different problems as well as the different regions. Legislative regulation must therefore provide the mechanisms and stable frameworks for participation. In turn however, it must also establish dynamic systems capable of adapting to and incorporating the varying demands and methods of participation coming from the public in response to disparate processes.

  5. A Management Strategy for the Naval Administrative Telephone System,

    Science.gov (United States)

    1985-03-01

    NARDACNET) which is purchasing up to ninety-nine electronic mailservers to provide EMAIL support service. These electronic mailservers are expected to be on...line by the end of 1985. Defense Data Network (DDIN) electronic mail (DD.lMail) mailservers (ownel by DCA) are currently oi~erating at max-zum capacity

  6. Internationalization Motivations and Strategies of Israeli Educational Administration Programs

    Science.gov (United States)

    Yemini, Miri; Giladi, Aviva

    2015-01-01

    Internationalization became a mainstreamed goal of almost every higher education institution, and institutions are expected to proactively implement this process. Although as an academic discipline, education is considered to be one of the most context-related and locally oriented ones, it had not avoided pressures to internationalize. Within the…

  7. Law Tackling Administrative Monopolies

    Institute of Scientific and Technical Information of China (English)

    WAN LIXIN

    2006-01-01

    @@ The long-anticipated anti-monopoly law needs to better address the crucial distinction between administrative and economic monopolies The first five months of 2oo6 saw a surge in the profits achieved by key State enterprises, especially in the eight sectors including petroleum, telecommunication and electricity, which achieved 285 billion yuan (US$36 billion) in profits, accounting for about 86 percent of the total, according to a July report. From the Stateowned Assets Supervision and Administration Commission of the State (SASAC). This news was both heartening and disquieting, for the most profitable sectors happen to be monopolistic enterprises, mostly upstream the production chain, who achieve their profitability at the expense of those companies further downstream. For years these sectors have been at the centre of the "bust-the-trust" storm.

  8. ATLAS TDAQ System Administration:

    CERN Document Server

    Lee, Christopher Jon; The ATLAS collaboration; Bogdanchikov, Alexander; Ballestrero, Sergio; Contescu, Alexandru Cristian; Dubrov, Sergei; Fazio, Daniel; Korol, Aleksandr; Scannicchio, Diana; Twomey, Matthew Shaun; Voronkov, Artem

    2015-01-01

    The ATLAS Trigger and Data Acquisition (TDAQ) system is responsible for the online processing of live data, streaming from the ATLAS experiment at the Large Hadron Collider (LHC) at CERN. The online farm is composed of ̃3000 servers, processing the data readout from ̃100 million detector channels through multiple trigger levels. During the two years of the first Long Shutdown (LS1) there has been a tremendous amount of work done by the ATLAS TDAQ System Administrators, implementing numerous new software applications, upgrading the OS and the hardware, changing some design philosophies and exploiting the High Level Trigger farm with different purposes. During the data taking only critical security updates are applied and broken hardware is replaced to ensure a stable operational environment. The LS1 provided an excellent opportunity to look into new technologies and applications that would help to improve and streamline the daily tasks of not only the System Administrators, but also of the scientists who wil...

  9. Investigation of Early Plasma Evolution Induced by Ultrashort Laser Pulses

    Science.gov (United States)

    Hu, Wenqian; Shin, Yung C.; King, Galen B.

    2012-01-01

    Early plasma is generated owing to high intensity laser irradiation of target and the subsequent target material ionization. Its dynamics plays a significant role in laser-material interaction, especially in the air environment1-11. Early plasma evolution has been captured through pump-probe shadowgraphy1-3 and interferometry1,4-7. However, the studied time frames and applied laser parameter ranges are limited. For example, direct examinations of plasma front locations and electron number densities within a delay time of 100 picosecond (ps) with respect to the laser pulse peak are still very few, especially for the ultrashort pulse of a duration around 100 femtosecond (fs) and a low power density around 1014 W/cm2. Early plasma generated under these conditions has only been captured recently with high temporal and spatial resolutions12. The detailed setup strategy and procedures of this high precision measurement will be illustrated in this paper. The rationale of the measurement is optical pump-probe shadowgraphy: one ultrashort laser pulse is split to a pump pulse and a probe pulse, while the delay time between them can be adjusted by changing their beam path lengths. The pump pulse ablates the target and generates the early plasma, and the probe pulse propagates through the plasma region and detects the non-uniformity of electron number density. In addition, animations are generated using the calculated results from the simulation model of Ref. 12 to illustrate the plasma formation and evolution with a very high resolution (0.04 ~ 1 ps). Both the experimental method and the simulation method can be applied to a broad range of time frames and laser parameters. These methods can be used to examine the early plasma generated not only from metals, but also from semiconductors and insulators. PMID:22806170

  10. Excitation Waveform Design for Lamb Wave Pulse Compression.

    Science.gov (United States)

    Lin, Jing; Hua, Jiadong; Zeng, Liang; Luo, Zhi

    2016-01-01

    Most ultrasonic guided wave methods focus on tone burst excitation to reduce the effect of dispersion so as to facilitate signal interpretation. However, the resolution of the output cannot attain a very high value because time duration of the excitation waveform cannot be very small. To overcome this limitation, a pulse compression technique is introduced to Lamb wave propagation to achieve a δ-like correlation so as to obtain a high resolution for inspection. Ideal δ-like correlation is impossible as only a finite frequency bandwidth can propagate. The primary purpose of this paper is to design a proper excitation waveform for Lamb wave pulse compression, which shortens the correlation as close as possible to a δ function. To achieve this purpose, the performance of some typical signals is discussed in pulse compression, which include linear chirp (L-Chirp) signal, nonlinear chirp (NL-Chirp) signal, Barker code (BC), and Golay complementary code (GCC). In addition, how the excitation frequency range influences inspection resolution is investigated. A strategy for the frequency range determination is established subsequently. Finally, an experiment is carried out on an aluminum plate where these typical signals are used as excitations at different frequency ranges. The quantitative comparisons of the pulse compression responses validate the theoretical findings. By utilizing the experimental data, the improvement of pulse compression in resolution compared with tone burst excitation is also validated, and the robustness of the waveform design method to inaccuracies in the dispersion compensation is discussed as well.

  11. A versatile computer-controlled pulsed nuclear quadrupole resonance spectrometer

    Science.gov (United States)

    Fisher, Gregory; MacNamara, Ernesto; Santini, Robert E.; Raftery, Daniel

    1999-12-01

    A new, pulsed nuclear quadrupole resonance (NQR) spectrometer capable of performing a variety of pulsed and swept experiments is described. The spectrometer features phase locked, superheterodyne detection using a commercial spectrum analyzer and a fully automatic, computer-controlled tuning and matching network. The tuning and matching network employs stepper motors which turn high power air gap capacitors in a "moving grid" optimization strategy to minimize the reflected power from a directional coupler. In the duplexer circuit, digitally controlled relays are used to switch different lengths of coax cable appropriate for the different radio frequencies. A home-built pulse programmer card controls the timing of radio frequency pulses sent to the probe, while data acquisition and control software is written in Microsoft Quick Basic. Spin-echo acquisition experiments are typically used to acquire the data, although a variety of pulse sequences can be employed. Scan times range from one to several hours depending upon the step resolution and the spectral range required for each experiment. Pure NQR spectra of NaNO2 and 3-aminopyridine are discussed.

  12. Humanism, Administration and Education

    DEFF Research Database (Denmark)

    Plum, Maja

    2012-01-01

    Abstract Through the example of a Danish reform of educational plans in early childhood education, this paper analyses the emergence of a new pedagogical desire related to administrative educational reforms promoting accountability, visibility and documentation. Two arguments are made: first, it ...... the ‘professional nursery teacher’ is produced as a reflective daily researcher, who outlives her pedagogical desire as an analytical care for the optimisation of the ‘learning child’....

  13. IPv6 Network Administration

    CERN Document Server

    Murphy, Niall Richard

    2009-01-01

    This essential guide explains what works, what doesn't, and most of all, what's practical about IPv6--the next-generation Internet standard. A must-have for network administrators everywhere looking to fix their network's scalability and management problems. Also covers other IPv6 benefits, such as routing, integrated auto-configuration, quality-of-services (QoS), enhanced mobility, and end-to-end security.

  14. Flexible Land Administration

    DEFF Research Database (Denmark)

    Enemark, Stig

    2014-01-01

    Security of tenure is widely considered to be the missing piece of the puzzle when it comes to eradication of poverty. And, as explained in the previous issue of Geoinformatics, the European Union is now placing land rights at the heart of EU development policy. This article presents a way forwar...... in terms of building flexible and "fit-for-purpose" land administration systems in developing countries. This will ensure security of tenure for all and sustainable management of the use of land....

  15. Flexible Land Administration

    DEFF Research Database (Denmark)

    Enemark, Stig

    2014-01-01

    Security of tenure is widely considered to be the missing piece of the puzzle when it comes to eradication of poverty. And, as explained in the previous issue of Geoinformatics, the European Union is now placing land rights at the heart of EU development policy. This article presents a way forwar...... in terms of building flexible and "fit-for-purpose" land administration systems in developing countries. This will ensure security of tenure for all and sustainable management of the use of land....

  16. Moodle administration essentials

    CERN Document Server

    Henrick, Gavin

    2015-01-01

    If you are an experienced system administrator and know how to manage servers and set up web environments but now want to explore Moodle, this book is perfect for you. You'll get to grips with the basics and learn to manage Moodle quickly, focusing on essential tasks. Having prior knowledge of virtual learning environments would be beneficial, but is not mandatory to make the most of this book.

  17. 7. Administrative structures.

    Science.gov (United States)

    2014-05-01

    The basic systems of any society rarely can operate independently. Instead, they are dependent and often interdependent upon other entities. Such entities control the resources within their respective systems. Thus, coordination and control agencies require contracts or memoranda of understanding with these entities in order to assure access to the resources required during a crisis. These administrative structures include: (1) governmental institutions and agencies, including the military; (2) intergovernmental organisations; (3) nongovernmental organisations; (4) commercial private sector organisations; and (5) academic institutions. These dependencies create potential barriers to the provision of coordination and control including: (1) the complexity of the administrative structures with which coordination and control must interact; (2) the location of resources; (3) finding responsible person(s); (4) the competence and compatibility; (5) methods of access; (6) payment; (7) contracts and memoranda of understanding; (8) inventories of accessible resources; (9) competition for the mandate, power, and resources; and (10) jealousy. The need for potential interactions between administrative structures requires that agreements for the sharing of resources during crises be reached as part of planning and preparedness. Gaining an understanding of these relationships is an important area for research.

  18. Square pulse linear transformer driver

    Directory of Open Access Journals (Sweden)

    A. A. Kim

    2012-04-01

    Full Text Available The linear transformer driver (LTD technological approach can result in relatively compact devices that can deliver fast, high current, and high-voltage pulses straight out of the LTD cavity without any complicated pulse forming and pulse compression network. Through multistage inductively insulated voltage adders, the output pulse, increased in voltage amplitude, can be applied directly to the load. The usual LTD architecture [A. A. Kim, M. G. Mazarakis, V. A. Sinebryukhov, B. M. Kovalchuk, V. A. Vizir, S. N Volkov, F. Bayol, A. N. Bastrikov, V. G. Durakov, S. V. Frolov, V. M. Alexeenko, D. H. McDaniel, W. E. Fowler, K. LeCheen, C. Olson, W. A. Stygar, K. W. Struve, J. Porter, and R. M. Gilgenbach, Phys. Rev. ST Accel. Beams 12, 050402 (2009PRABFM1098-440210.1103/PhysRevSTAB.12.050402; M. G. Mazarakis, W. E. Fowler, A. A. Kim, V. A. Sinebryukhov, S. T. Rogowski, R. A. Sharpe, D. H. McDaniel, C. L. Olson, J. L. Porter, K. W. Struve, W. A. Stygar, and J. R. Woodworth, Phys. Rev. ST Accel. Beams 12, 050401 (2009PRABFM1098-440210.1103/PhysRevSTAB.12.050401] provides sine shaped output pulses that may not be well suited for some applications like z-pinch drivers, flash radiography, high power microwaves, etc. A more suitable power pulse would have a flat or trapezoidal (rising or falling top. In this paper, we present the design and first test results of an LTD cavity that generates such a type of output pulse by including within its circular array a number of third harmonic bricks in addition to the main bricks. A voltage adder made out of a square pulse cavity linear array will produce the same shape output pulses provided that the timing of each cavity is synchronized with the propagation of the electromagnetic pulse.

  19. High-Altitude Electromagnetic Pulse (HEMP) Testing

    Science.gov (United States)

    2015-07-09

    Electromagnetic Pulse Horizontal Electromagnetic Pulse Advanced Fast Electromagnetic Pulse Nuclear Weapons Effect Testing and Environments 16. SECURITY...TOP 01-2-620A 9 July 2015 G-1 APPENDIX G. ABBREVIATIONS. AFEMP Advanced Fast Electromagnetic ... Electromagnetic Pulse A burst of electromagnetic radiation from a nuclear explosion or a suddenly fluctuating magnetic field. The resulting electric and

  20. Electroporation adopting trains of biphasic pulses enhances in vitro and in vivo the cytotoxic effect of doxorubicin on multidrug resistant colon adenocarcinoma cells (LoVo).

    Science.gov (United States)

    Meschini, Stefania; Condello, Maria; Lista, Pasquale; Vincenzi, Bruno; Baldi, Alfonso; Citro, Gennaro; Arancia, Giuseppe; Spugnini, Enrico P

    2012-09-01

    Few articles in the literature have focused on electroporation as a strategy to reverse multidrug resistance (MDR) of tumour cells and they are mostly limited to the improved efficacy of bleomycin. We tested the application of trains of biphasic pulses to cell suspensions and to murine xenografts as a strategy to increase the uptake of doxorubicin (DOX) and to enhance its cytotoxicity against chemoresistant cells. The human colon adenocarcinoma cell line LoVo DX, expressing MDR phenotype with high levels of P-glycoprotein (P-gp), has been used. The in vitro and in vivo studies gave the following results: (i) the application of the electric pulses to the cell suspension, immediately before DOX administration, induced a significant increase of drug retention; (ii) confocal microscopy observations showed a remarkable increase of intranuclear accumulation of DOX induced by electroporation; (iii) cell survival assay revealed a decrease of cell viability in the cultures treated with the combination of electroporation and doxorubicin; (iv) scanning electron microscopy observations revealed consistent morphological changes after the combined exposure to electroporation and doxorubicin; (v) in implanted mice the combined treatment induced an evident slowdown on the tumour growth when compared to treatment with DOX alone; (vi) histopathological analysis evidenced tumour destruction and its replacement by scar tissue in the tumours treated with the combination of doxorubicin and electroporation.

  1. Intense ultrashort terahertz pulses: generation and applications

    Energy Technology Data Exchange (ETDEWEB)

    Hoffmann, Matthias C [Max Planck Research Department for Structural Dynamics, University of Hamburg, CFEL, 22607 Hamburg (Germany); Fueloep, Jozsef Andras, E-mail: matthias.c.hoffmann@mpsd.cfel.de, E-mail: fulop@fizika.ttk.pte.hu [Department of Experimental Physics, University of Pecs, Ifjusag u. 6, 7624 Pecs (Hungary)

    2011-03-02

    Ultrashort terahertz pulses derived from femtosecond table-top sources have become a valuable tool for time-resolved spectroscopy during the last two decades. Until recently, the pulse energies and field strengths of these pulses have been generally too low to allow for the use as pump pulses or the study of nonlinear effects in the terahertz range. In this review article we will describe methods of generation of intense single cycle terahertz pulses with emphasis on optical rectification using the tilted-pulse-front pumping technique. We will also discuss some applications of these intense pulses in the emerging field of nonlinear terahertz spectroscopy. (topical review)

  2. CONSIDERATIONS UPON ASSIMILATED ADMINISTRATIVE ACTS

    OpenAIRE

    2011-01-01

    Although the classic administrative courts know as object the acts against classic administrative acts, it should not be lost sight of the assimilated administrative acts, which also may be subject to acts in this litigation. Taking in consideration this category of acts, this study will examine the documents falling into this category and the impact that such acts have on public authorities. Given the significant increase of administrative cases that have as object assimilated administrative...

  3. Pulse compression and prepulse suppression apparatus

    Science.gov (United States)

    Dane, C.B.; Hackel, L.A.; George, E.V.; Miller, J.L.; Krupke, W.F.

    1993-11-09

    A pulse compression and prepulse suppression apparatus (10) for time compressing the output of a laser (14). A pump pulse (46) is separated from a seed pulse (48) by a first polarized beam splitter (20) according to the orientation of a half wave plate (18). The seed pulse (48) is directed into an SBS oscillator (44) by two plane mirrors (22, 26) and a corner mirror (24), the corner mirror (24) being movable to adjust timing. The pump pulse (46) is directed into an SBS amplifier 34 wherein SBS occurs. The seed pulse (48), having been propagated from the SBS oscillator (44), is then directed through the SBS amplifier (34) wherein it sweeps the energy of the pump pulse (46) out of the SBS amplifier (34) and is simultaneously compressed, and the time compressed pump pulse (46) is emitted as a pulse output (52). A second polarized beam splitter (38) directs any undepleted pump pulse 58 away from the SBS oscillator (44).

  4. Consecutive Bright Pulses in the Vela Pulsar

    CERN Document Server

    Palfreyman, Jim L; Dickey, John M; Young, Timothy G; Hotan, Claire E; 10.1088/2041-8205/735/1/L17

    2011-01-01

    We report on the discovery of consecutive bright radio pulses from the Vela pulsar, a new phenomenon that may lead to a greater understanding of the pulsar emission mechanism. This results from a total of 345 hr worth of observations of the Vela pulsar using the University of Tasmania's 26 m radio telescope to study the frequency and statistics of abnormally bright pulses and sub-pulses. The bright pulses show a tendency to appear consecutively. The observations found two groups of six consecutive bright pulses and many groups of two to five bright pulses in a row. The strong radio emission process that produces the six bright pulses lasts between 0.4 and 0.6 s. The numbers of bright pulses in sequence far exceed what would be expected if individual bright pulses were independent random events. Consecutive bright pulses must be generated by an emission process that is long lived relative to the rotation period of the neutron star.

  5. High-voltage, short-risetime pulse generator based on a ferrite pulse sharpener

    Energy Technology Data Exchange (ETDEWEB)

    Seddon, N.; Thornton, E.

    1988-11-01

    A high-voltage, short-risetime pulse generator is described. The generator consists of a Marx bank, which produces an initial high-voltage pulse, and a ferrite pulse sharpener that reduces the risetime of the pulse. The generator delivers 70-kV, 350-ps risetime pulses into a 50-..cap omega.. load.

  6. The coherent artifact in modern pulse measurements

    CERN Document Server

    Ratner, Justin; Wong, Tsz Chun; Bartels, Randy; Trebino, Rick

    2012-01-01

    We simulate multi-shot intensity-and-phase measurements of unstable ultrashort-pulse trains using frequency-resolved-optical-gating (FROG) and spectral phase interferometry for direct electric-field reconstruction (SPIDER). Both techniques fail to reveal the pulse structure. FROG yields the average pulse duration and suggests the instability by exhibiting disagreement between measured and retrieved traces. SPIDER under-estimates the average pulse duration but retrieves the correct average pulse spectral phase. An analytical calculation confirms this behavior.

  7. Life After the George W. Bush Administration: A New US Strategy Towards China for Future Administrations

    Science.gov (United States)

    2008-05-15

    The Conference Board, “China’s Turbo Growth Not Sustainable Because of Growing Economic Imbalances ,” Earthtimes.org, December 3, 2007, under “Can...farmers, out of fear, began to fence off their lands to keep the nomads from using up the land and water to care for their camels and families. Eventually...January 3, 2008). 143 Gordon G. Chang, “China Flexes Its Muscles ,” in Wall Street Journal, January 2, 2008 under “Commentary,” http://online.wsj.com

  8. The pulsing CPSD method for subcritical assemblies with pulsed sources

    CERN Document Server

    Ballester, D; Ballester, Daniel; Munoz-Cobo, Jose L.

    2005-01-01

    Stochastic neutron transport theory is applied to the derivation of the two-neutron-detectors cross power spectral density for subcritical assemblies when external pulsed sources are used. A general relationship between the two-detector probability generating functions of the kernel and the source is obtained considering the contribution to detectors statistics of both the pulsed source and the intrinsic neutron source. An expansion in alpha-eigenvalues is derived for the final solution, which permits to take into account the effect of higher harmonics in subcritical systems. Further, expressions corresponding to the fundamental mode approximation are compared with recent results from experiments performed under the MUSE-4 European research project.

  9. High field rf superconductivity: to pulse or not to pulse

    Energy Technology Data Exchange (ETDEWEB)

    Campisi, I.E.

    1984-10-01

    Experimental data on the behavior of superconductors under the application of rf fields of amplitude comparable to their critical fields are sporadic and not always consistent. In many cases the field level at which breakdown in superconducting rf cavities should be expected has not been clearly established. Tests conducted with very short (approx. 1 ..mu..s) rf pulses indicate that in this mode of operation fields close to the critical values can be consistently reached in superconducting cavities without breakdown. The advantages and disadvantages of the pulsed method are discussed compared to those of the more standard continuous wave (cw) systems. 60 references.

  10. Development of pulsed positron beam line with compact pulsing system

    Energy Technology Data Exchange (ETDEWEB)

    Maekawa, Masaki, E-mail: maekawa.masaki@jaea.go.jp [Advanced Science Research Center, Japan Atomic Energy Agency, 1233 Watanuki, Takasaki, Gunma 370-1292 (Japan); Kawasuso, Atsuo [Advanced Science Research Center, Japan Atomic Energy Agency, 1233 Watanuki, Takasaki, Gunma 370-1292 (Japan)

    2012-01-01

    We have developed a pulsed slow positron beam with a pulse width of less than 200 ps and a period of 25 ns. The beam apparatus is composed of a Munich-type pre-buncher, a chopper and a buncher. Instead of the conventional RF cavity, a simple double-cylinder electrode is used for the buncher. The beam will be used for positron lifetime measurements. The time resolution of the whole system including lifetime measurement circuits is 250 ps, which is adequate for studying semiconductors and metals.

  11. Pre-earthquake magnetic pulses

    Directory of Open Access Journals (Sweden)

    J. Scoville

    2014-12-01

    Full Text Available A semiconductor model of rocks is shown to describe unipolar magnetic pulses, a phenomenon that has been observed prior to earthquakes. These pulses are generated deep in the Earth's crust, in and around the Hypocentral volume, days or even weeks before Earthquakes. They are observable at the surface because their extremely long wavelength allows them to pass through kilometers of rock. Interestingly, the source of these pulses may be triangulated to pinpoint locations where stresses are building deep within the crust. We couple a semiconductor drift-diffusion model to a magnetic field in order to describe the electromagnetic effects associated with electrical currents flowing within rocks. The resulting system of equations is solved numerically and it is seen that a volume of rock may act as a diode that produces transient currents when it switches bias. These unidirectional currents are expected to produce transient unipolar magnetic pulses similar in form, amplitude, and duration to those observed before earthquakes, and this suggests that the pulses could be the result of geophysical semiconductor processes.

  12. AIS, ADMINISTRATIVE INFORMATION SUPPORT

    CERN Multimedia

    AS-DB/AS-SU

    1999-01-01

    The AS-DB and AS-SU groups within the Administrative Support division now offer a central entry point to the computer based Information Services under their responsibilities: the AIS Web site at http://ais.cern.ch.It features comprehensive search and navigation facilities as well as an activity based business map to guide AIS users to the information they want. Users will be able to launch any AIS WEB application from its desktop.Enjoy a visit of the site, we value your feedback at ais.webmaster@cern.ch!AS-DB/AS-SU

  13. Does Gender of Administrator Matter? National Study Explores U.S. University Administrators' Attitudes About Retaining Women Professors in STEM

    Directory of Open Access Journals (Sweden)

    Wendy M. Williams

    2017-05-01

    Full Text Available Omnipresent calls for more women in university administration presume women will prioritize using resources and power to increase female representation, especially in STEM fields where women are most underrepresented. However, empirical evidence is lacking for systematic differences in female vs. male administratorsŠ attitudes. Do female administrators agree on which strategies are best, and do men see things differently? We explored United States college and university administratorsŠ opinions regarding strategies, policies, and structural changes in their organizations designed to increase women professorsŠ representation and retention in STEM fields. A comprehensive review of past research yielded a database of potentially-effective, recommended policies. A survey based on these policies was sent to provosts, deans, associate deans, and department chairs of STEM fields at 96 public and private research universities across the U.S. These administrators were asked to rate the quality and feasibility of each strategy; 474 provided data, of which 334 contained complete numerical data used in the analyses. Our data revealed that female (vs. male administrators believed the 44 strategies were higher in quality overall—but not higher in feasibility—with 9 strategies perceived differently by women and men, after imposing conservative statistical controls. There was broad general agreement on the relative-quality rankings of the 44 strategies. Women (vs. men gave higher quality ratings to increasing the value of teaching, service, and administrative experience in tenure/promotion decisions, increasing flexibility of federal-grant funding to accommodate mothers, conducting gender-equity research, and supporting shared tenure lines enabling work-life balance. Women (vs. men believed it was more feasible for men to stop the tenure clock for 1 year for childrearing and for universities to support requests for shared tenure lines, but less

  14. Does Gender of Administrator Matter? National Study Explores U.S. University Administrators' Attitudes About Retaining Women Professors in STEM.

    Science.gov (United States)

    Williams, Wendy M; Mahajan, Agrima; Thoemmes, Felix; Barnett, Susan M; Vermeylen, Francoise; Cash, Brian M; Ceci, Stephen J

    2017-01-01

    Omnipresent calls for more women in university administration presume women will prioritize using resources and power to increase female representation, especially in STEM fields where women are most underrepresented. However, empirical evidence is lacking for systematic differences in female vs. male administratorsŠ attitudes. Do female administrators agree on which strategies are best, and do men see things differently? We explored United States college and university administratorsŠ opinions regarding strategies, policies, and structural changes in their organizations designed to increase women professorsŠ representation and retention in STEM fields. A comprehensive review of past research yielded a database of potentially-effective, recommended policies. A survey based on these policies was sent to provosts, deans, associate deans, and department chairs of STEM fields at 96 public and private research universities across the U.S. These administrators were asked to rate the quality and feasibility of each strategy; 474 provided data, of which 334 contained complete numerical data used in the analyses. Our data revealed that female (vs. male) administrators believed the 44 strategies were higher in quality overall-but not higher in feasibility-with 9 strategies perceived differently by women and men, after imposing conservative statistical controls. There was broad general agreement on the relative-quality rankings of the 44 strategies. Women (vs. men) gave higher quality ratings to increasing the value of teaching, service, and administrative experience in tenure/promotion decisions, increasing flexibility of federal-grant funding to accommodate mothers, conducting gender-equity research, and supporting shared tenure lines enabling work-life balance. Women (vs. men) believed it was more feasible for men to stop the tenure clock for 1 year for childrearing and for universities to support requests for shared tenure lines, but less feasible for women to

  15. Environmental strategy

    DEFF Research Database (Denmark)

    Zabkar, Vesna; Cater, Tomaz; Bajde, Domen

    2013-01-01

    perspective, appropriate environmental strategies in compliance with environmental requirements aim at building competitive advantages through sustainable development. There is no universal “green” strategy that would be appropriate for each company, regardless of its market requirements and competitive...... situations. Instead, managers undertake careful consideration of the circumstances in which their company operates, paying special attention to their customers’ environmental preferences....

  16. Evaluation Strategy

    DEFF Research Database (Denmark)

    Coto Chotto, Mayela; Wentzer, Helle; Dirckinck-Holmfeld, Lone

    2009-01-01

    The paper presents an evaluation strategy based on deliberate ideals and principles of dialogue design. The evaluation strategy is based on experiential phenomenology taking the point of departure for design and evaluation processes in the experienced practitioners themselves. The article present...... the evaluation strategy and methodology of a research project Making Online Path to Enter new Markets, MOPEM. It is an EU-research project with partners from different Educational Institutions of Technology and Business in five European Countries.......The paper presents an evaluation strategy based on deliberate ideals and principles of dialogue design. The evaluation strategy is based on experiential phenomenology taking the point of departure for design and evaluation processes in the experienced practitioners themselves. The article presents...

  17. Evaluation Strategy

    DEFF Research Database (Denmark)

    Coto Chotto, Mayela; Wentzer, Helle; Dirckinck-Holmfeld, Lone

    2009-01-01

    The paper presents an evaluation strategy based on deliberate ideals and principles of dialogue design. The evaluation strategy is based on experiential phenomenology taking the point of departure for design and evaluation processes in the experienced practitioners themselves. The article present...... the evaluation strategy and methodology of a research project Making Online Path to Enter new Markets, MOPEM. It is an EU-research project with partners from different Educational Institutions of Technology and Business in five European Countries.......The paper presents an evaluation strategy based on deliberate ideals and principles of dialogue design. The evaluation strategy is based on experiential phenomenology taking the point of departure for design and evaluation processes in the experienced practitioners themselves. The article presents...

  18. Methylprednisolone pulsing of heart transplant patients in the home.

    Science.gov (United States)

    Miska, P T; Bates, L R; Collins, C L; Bolling, S F; Deeb, G M

    1988-01-01

    Methylprednisolone pulsing is the first form of treatment used to reverse acute moderate rejection in heart transplant patients at the University of Michigan, Ann Arbor. Before May 1986, patients who needed administration of medications to be pulsed were admitted to the hospital. With our increasing number of transplant patients, lack of hospital beds, and efforts toward cost containment, a new system was established. From June 1986 to April 1988, 53 heart transplantations were performed in 40 adults and 13 children. Home care agency nurses received in-service training by the heart transplant clinical specialist. Insurance companies were contacted directly to obtain financial approval when it was not considered a covered benefit. Of 47 episodes of rejection, 45 were successfully treated in the home with resolution, whereas hospital admission was required in two cases of rejection episodes for successful resolution. There were marked financial savings, increased patient satisfaction, no patient infections, and minimal side effects, which included hypertension in five patients, headaches in two patients, and difficulty gaining venous access in two patients. Most problems were easily handled by telephone communication. Therefore, after a 22-month experience with administration of methylprednisolone pulses in the home, we believe that this is a satisfactory method of treating patients. It is cost-effective, has minimal side effects, and leads to increased patient satisfaction.

  19. Pulsed discharge production Ar* metastables

    Science.gov (United States)

    Han, Jiande; Heaven, Michael C.; Emmons, Daniel; Perram, Glen P.; Weeks, David E.; Bailey, William F.

    2016-03-01

    The production of relatively high densities of Ar* metastables (>1012 cm-3) in Ar/He mixtures, at total pressures close to 1 atm, is essential for the efficient operation of an optically pumped Ar* laser. We have used emission spectroscopy and diode laser absorption spectroscopy measurements to observe the production and decay of Ar* in a parallel plate pulsed discharge. With discharge pulses of 1 μs duration we find that metastable production is dominated by processes occurring within the first 100 ns of the gas break-down. Application of multiple, closely spaced discharge pulses yields insights concerning conditions that favor metastable production. This information has been combined with time-resolved measurements of voltage and current. The experimental results and preliminary modeling of the discharge kinetics are presented.

  20. Zeptosecond $\\gamma$-ray pulses

    CERN Document Server

    Klaiber, Michael; Keitel, Christoph H

    2007-01-01

    High-order harmonic generation (HHG) in the relativistic regime is employed to obtain zeptosecond pulses of $\\gamma$-rays. The harmonics are generated from atomic systems in counterpropagating strong attosecond laser pulse trains of linear polarization. In this setup recollisions of the ionized electrons can be achieved in the highly relativistic regime via a reversal of the commonly deteriorating drift and without instability of the electron dynamics such as in a standing laser wave. As a result, coherent attosecond $\\gamma$-rays in the 10 MeV energy range as well as coherent zeptosecond $\\gamma$-ray pulses of MeV photon energy for time-resolved nuclear spectroscopy become feasible.

  1. Dynamic parabolic pulse generation using temporal shaping of wavelength to time mapped pulses.

    Science.gov (United States)

    Nguyen, Dat; Piracha, Mohammad Umar; Mandridis, Dimitrios; Delfyett, Peter J

    2011-06-20

    Self-phase modulation in fiber amplifiers can significantly degrade the quality of compressed pulses in chirped pulse amplification systems. Parabolic pulses with linear frequency chirp are suitable for suppressing nonlinearities, and to achieve high peak power pulses after compression. In this paper, we present an active time domain technique to generate parabolic pulses for chirped pulse amplification applications. Pulses from a mode-locked laser are temporally stretched and launched into an amplitude modulator, where the drive voltage is designed using the spectral shape of the input pulse and the transfer function of the modulator, resulting in the generation of parabolic pulses. Experimental results of pulse shaping with a pulse train from a mode-locked laser are presented, with a residual error of less than 5%. Moreover, an extinction ratio of 27 dB is achieved, which is ideal for chirped pulse amplification applications.

  2. Administration of Educational Services: A Glossary of Basic Administration Terminology.

    Science.gov (United States)

    Wheelbarger, J. J.

    From "achievement motivation" and "administration" to "Theory Z" and "viscidity and hedonic tone," this glossary defines 87 terms as they are used in educational administration. The terms include philosophical, psychological, organizational, and social concepts, but they all are employed in the theory and practice of administration. A short…

  3. Administrative role and educational administration program effectiveness: perception by principals.

    Science.gov (United States)

    Yap, C; Katz, B; Tomazic, T

    1991-12-01

    A survey of 85 graduates from 14 midwestern universities offering doctoral degrees in educational administration was carried out to assess perceptions of graduates regarding their training program. The emphasis of the survey was on how closely their training corresponded to current perceptions of their roles as educational administrators. Most indicated emphasis in graduate training should more closely match the roles of administrators.

  4. Behavioral Public Administration : Combining Insights from Public Administration and Psychology

    NARCIS (Netherlands)

    Grimmelikhuijsen, S.G.|info:eu-repo/dai/nl/313875405; Jilke, Sebastian; Leth Olsen, Asmus; Tummers, L.G.

    2016-01-01

    Behavioral public administration is the analysis of public administration from the micro-perspective of individual behavior and attitudes by drawing upon insights from psychology on behavior of individuals and groups. We discuss how scholars in public administration currently draw on theories and

  5. 47 CFR 54.715 - Administrative expenses of the Administrator.

    Science.gov (United States)

    2010-10-01

    ... support mechanism, the low income support mechanism, the interstate access universal service support... SERVICES (CONTINUED) UNIVERSAL SERVICE Administration § 54.715 Administrative expenses of the Administrator... an amount not to exceed the rate of basic pay in effect for Level I of the Executive Schedule under...

  6. Behavioral Public Administration : Combining Insights from Public Administration and Psychology

    NARCIS (Netherlands)

    Grimmelikhuijsen, S.G.; Jilke, Sebastian; Leth Olsen, Asmus; Tummers, L.G.

    2016-01-01

    Behavioral public administration is the analysis of public administration from the micro-perspective of individual behavior and attitudes by drawing upon insights from psychology on behavior of individuals and groups. We discuss how scholars in public administration currently draw on theories and me

  7. Supersonic Jet Noise Reduction Using Flapping Injection and Pulsed Injection

    Science.gov (United States)

    Hafsteinsson, Haukur; Eriksson, Lars-Erik; Cuppoletti, Daniel; Gutmark, Ephraim; Department of Applied Mechanics, Chalmers University of Technology Team; Department of Aerospace Engineering, University of Cincinatti Team; Swedish Defence Material Administration, Sweden Team

    2013-11-01

    Aircraft are in general noisy and there is a high demand for reducing their noise levels. The jet exhaust is in most cases the main noise source of the aircraft, especially for low bypass ratio jet engines. Fluidic injection affecting the shear layer close to the nozzle exit is a promising noise reduction technique as it can be turned of while not needed and thus the negative effect on the engine performance will be minimized. In the presented work, LES is used to compare steady-state mass flow injection with steady-state mass flow flapping jet injection. The work is a direct continuation of a previous LES study on pulsed injection which showed that the pulsed injection induced pressure pulses in the jet which caused increased tonal noise in the downstream directions. The injection system considered in the presented work consists of eight evenly distributed injectors at the nozzle exit plane with a 90° injection angle relative to the flow direction. Flapping jet injection is believed to minimize the creation of these pressure pulses since it provides steady-state mass flow. This work is funded by Swedish Defense Material Administration (FMV).

  8. Liquid micro pulsed plasma thruster

    Directory of Open Access Journals (Sweden)

    Szelecka Agnieszka

    2015-06-01

    Full Text Available A new type of pulsed plasma thruster (PPT for small satellite propulsion is investigated, of which the most innovative aspect is the use of a non-volatile liquid propellant. The thruster is based on an open capillary design. The thruster achieved a thrust-to-power ratio above 45 μN/W, which constitutes a 5-fold improvement over the water-propelled pulsed plasma thruster, and which is also slightly above the performance of a similarly sized PPT with a solid propellant.

  9. Pulse compressor with aberration correction

    Energy Technology Data Exchange (ETDEWEB)

    Mankos, Marian [Electron Optica, Inc., Palo Alto, CA (United States)

    2015-11-30

    In this SBIR project, Electron Optica, Inc. (EOI) is developing an electron mirror-based pulse compressor attachment to new and retrofitted dynamic transmission electron microscopes (DTEMs) and ultrafast electron diffraction (UED) cameras for improving the temporal resolution of these instruments from the characteristic range of a few picoseconds to a few nanoseconds and beyond, into the sub-100 femtosecond range. The improvement will enable electron microscopes and diffraction cameras to better resolve the dynamics of reactions in the areas of solid state physics, chemistry, and biology. EOI’s pulse compressor technology utilizes the combination of electron mirror optics and a magnetic beam separator to compress the electron pulse. The design exploits the symmetry inherent in reversing the electron trajectory in the mirror in order to compress the temporally broadened beam. This system also simultaneously corrects the chromatic and spherical aberration of the objective lens for improved spatial resolution. This correction will be found valuable as the source size is reduced with laser-triggered point source emitters. With such emitters, it might be possible to significantly reduce the illuminated area and carry out ultrafast diffraction experiments from small regions of the sample, e.g. from individual grains or nanoparticles. During phase I, EOI drafted a set of candidate pulse compressor architectures and evaluated the trade-offs between temporal resolution and electron bunch size to achieve the optimum design for two particular applications with market potential: increasing the temporal and spatial resolution of UEDs, and increasing the temporal and spatial resolution of DTEMs. Specialized software packages that have been developed by MEBS, Ltd. were used to calculate the electron optical properties of the key pulse compressor components: namely, the magnetic prism, the electron mirror, and the electron lenses. In the final step, these results were folded

  10. High-speed pulse techniques

    CERN Document Server

    Coekin, J A

    1975-01-01

    High-Speed Pulse Techniques covers the many aspects of technique in digital electronics and encompass some of the more fundamental factors that apply to all digital systems. The book describes the nature of pulse signals and their deliberate or inadvertent processing in networks, transmission lines and transformers, and then examines the characteristics and transient performance of semiconductor devices and integrated circuits. Some of the problems associated with the assembly of these into viable systems operating at ultra high speed are also looked at. The book examines the transients and w

  11. Neuromuscular disruption with ultrashort electrical pulses

    Science.gov (United States)

    Pakhomov, Andrei; Kolb, Juergen F.; Joshi, Ravindra P.; Schoenbach, Karl H.; Dayton, Thomas; Comeaux, James; Ashmore, John; Beason, Charles

    2006-05-01

    Experimental studies on single cells have shown that application of pulsed voltages, with submicrosecond pulse duration and an electric field on the order of 10 kV/cm, causes sudden alterations in the intracellular free calcium concentration, followed by immobilization of the cell. In order to examine electrical stimulation and incapacitation with such ultrashort pulses, experiments on anesthetized rats have been performed. The effect of single, 450 nanosecond monopolar pulses have been compared with that of single pulses with multi-microsecond duration (TASER pulses). Two conditions were explored: 1. the ability to elicit a muscle twitch, and, 2. the ability to suppress voluntary movement by using nanosecond pulses. The second condition is relevant for neuromuscular incapacitation. The preliminary results indicate that for stimulation microsecond pulses are advantageous over nanosecond pulses, whereas for incapacitation, the opposite seems to apply. The stimulation effects seem to scale with electrical charge, whereas the disruption effects don't follow a simple scaling law. The increase in intensity (time of incapacitation) for a given pulse duration, is increasing with electrical energy, but is more efficient for nanosecond than for microsecond pulses. This indicates different cellular mechanisms for incapacitation, most likely subcellular processes, which have been shown to become increasingly important when the pulse duration is shortened into the nanosecond range. If further studies can confirm these initial results, consequences of reduced pulse duration are a reduction in weight and volume of the pulse delivery system, and likely, because of the lower required energy for neuromuscular incapacitation, reduced safety risks.

  12. Control of high power pulse extracted from the maximally compressed pulse in a nonlinear optical fiber

    CERN Document Server

    Yang, Guangye; Jia, Suotang; Mihalache, Dumitru

    2013-01-01

    We address the possibility to control high power pulses extracted from the maximally compressed pulse in a nonlinear optical fiber by adjusting the initial excitation parameters. The numerical results show that the power, location and splitting order number of the maximally compressed pulse and the transmission features of high power pulses extracted from the maximally compressed pulse can be manipulated through adjusting the modulation amplitude, width, and phase of the initial Gaussian-type perturbation pulse on a continuous wave background.

  13. Pulse Delay and Speed-up of Ultra Fast Pulses in an Absorbing Quantum Well Medium

    DEFF Research Database (Denmark)

    Hansen, Per Lunnemann; Poel, Mike van der; Yvind, Kresten;

    2008-01-01

    Slow down and speed-up of 180 fs pulses in an absorbing semiconductor beyond the exisitng models is observed. Cascading gainand absorbing sections give us significant temporal pulse shifting at almost constant output pulse energy.......Slow down and speed-up of 180 fs pulses in an absorbing semiconductor beyond the exisitng models is observed. Cascading gainand absorbing sections give us significant temporal pulse shifting at almost constant output pulse energy....

  14. Dynamic Characterization of Fiber Optical Chirped Pulse Amplification for Sub-ps Pulses

    DEFF Research Database (Denmark)

    Cristofori, Valentina; Lali-Dastjerdi, Zohreh; Rishøj, Lars Søgaard

    2013-01-01

    We investigate experimentally the propagation of sub-picosecond pulses in fiber optical parametric chirped pulse amplifiers, showing a significant broadening of the pulses from 450 fs up to 720 fs due to dispersion and self-phase modulation.......We investigate experimentally the propagation of sub-picosecond pulses in fiber optical parametric chirped pulse amplifiers, showing a significant broadening of the pulses from 450 fs up to 720 fs due to dispersion and self-phase modulation....

  15. 35 Volt, 180 Ampere Pulse Generator with Droop Control for Pulsing Xenon Arcs

    DEFF Research Database (Denmark)

    Hviid, T.; Nielsen, S. O.

    1972-01-01

    The pulse generator described works as a combined switch and series current regulator and allows the shape of the current pulse to be adjusted at each optical wavelength to produce a flat pulse of monochromatic light.......The pulse generator described works as a combined switch and series current regulator and allows the shape of the current pulse to be adjusted at each optical wavelength to produce a flat pulse of monochromatic light....

  16. Pulsed DC Electric Field-Induced Differentiation of Cortical Neural Precursor Cells.

    Directory of Open Access Journals (Sweden)

    Hui-Fang Chang

    Full Text Available We report the differentiation of neural stem and progenitor cells solely induced by direct current (DC pulses stimulation. Neural stem and progenitor cells in the adult mammalian brain are promising candidates for the development of therapeutic neuroregeneration strategies. The differentiation of neural stem and progenitor cells depends on various in vivo environmental factors, such as nerve growth factor and endogenous EF. In this study, we demonstrated that the morphologic and phenotypic changes of mouse neural stem and progenitor cells (mNPCs could be induced solely by exposure to square-wave DC pulses (magnitude 300 mV/mm at frequency of 100-Hz. The DC pulse stimulation was conducted for 48 h, and the morphologic changes of mNPCs were monitored continuously. The length of primary processes and the amount of branching significantly increased after stimulation by DC pulses for 48 h. After DC pulse treatment, the mNPCs differentiated into neurons, astrocytes, and oligodendrocytes simultaneously in stem cell maintenance medium. Our results suggest that simple DC pulse treatment could control the fate of NPCs. With further studies, DC pulses may be applied to manipulate NPC differentiation and may be used for the development of therapeutic strategies that employ NPCs to treat nervous system disorders.

  17. Pulsed DC Electric Field–Induced Differentiation of Cortical Neural Precursor Cells

    Science.gov (United States)

    Chang, Hui-Fang; Lee, Ying-Shan; Tang, Tang K.; Cheng, Ji-Yen

    2016-01-01

    We report the differentiation of neural stem and progenitor cells solely induced by direct current (DC) pulses stimulation. Neural stem and progenitor cells in the adult mammalian brain are promising candidates for the development of therapeutic neuroregeneration strategies. The differentiation of neural stem and progenitor cells depends on various in vivo environmental factors, such as nerve growth factor and endogenous EF. In this study, we demonstrated that the morphologic and phenotypic changes of mouse neural stem and progenitor cells (mNPCs) could be induced solely by exposure to square-wave DC pulses (magnitude 300 mV/mm at frequency of 100-Hz). The DC pulse stimulation was conducted for 48 h, and the morphologic changes of mNPCs were monitored continuously. The length of primary processes and the amount of branching significantly increased after stimulation by DC pulses for 48 h. After DC pulse treatment, the mNPCs differentiated into neurons, astrocytes, and oligodendrocytes simultaneously in stem cell maintenance medium. Our results suggest that simple DC pulse treatment could control the fate of NPCs. With further studies, DC pulses may be applied to manipulate NPC differentiation and may be used for the development of therapeutic strategies that employ NPCs to treat nervous system disorders. PMID:27352251

  18. Contratos de rendimiento para administradores (Performance Contracts for Administrators). ERIC Digest.

    Science.gov (United States)

    Hertling, Elizabeth

    This digest in Spanish explores the strategy of paying school administrators based on performance contracts. A performance contract is an agreement between an administrator--typically a superintendent--and the school board that links the administrator's pay to indicators of job performance. Most commonly, performance contracts include bonuses for…

  19. Abandono do tratamento de tuberculose utilizando-se as estratégias tratamento auto-administrado ou tratamento supervisionado no Programa Municipal de Carapicuíba, São Paulo, Brasil Noncompliance with tuberculosis treatment involving self administration of treatment or the directly observed therapy, short-course strategy in a tuberculosis control program in the city of Carapicuíba, Brazil

    Directory of Open Access Journals (Sweden)

    Amadeu Antonio Vieira

    2008-03-01

    Full Text Available OBJETIVO: Verificar as taxas de abandono e identificar as variáveis relacionadas ao abandono do tratamento, segundo o tipo de estratégia utilizada em pacientes matriculados no Programa de Controle da Tuberculose do município de Carapicuíba (SP Brasil. MÉTODO: Estudo longitudinal não concorrente de duas coortes de tratamento de tuberculose, a primeira de 1 de janeiro a 31 de dezembro de 2003 com a estratégia tratamento auto-administrado (173 casos e a segunda de 1 de julho de 2004 a 30 de junho de 2005 com a estratégia tratamento supervisionado (187 casos. RESULTADOS: A taxa de abandono diminuiu significativamente (p OBJECTIVE: To determine treatment noncompliance rates among patients participating in a municipal tuberculosis control program and to identify the variables related to noncompliance depending on the type of treatment strategy used. METHODS: A longitudinal non-concurrent cohort study was carried out involving two cohorts of patients participating in the Tuberculosis Control Program of the city of Carapicuíba, Brazil. The first cohort comprised 173 patients with tuberculosis treated from January 1, 2003 to December 31, 2003 using self administration of treatment, and the second comprised 187 patients with tuberculosis treated from July 1, 2004 to June 30, 2005 using the directly observed therapy, short-course strategy. RESULTS: Noncompliance rates decreased from 13.3% (self administration of treatment to 5.9% (directly observed therapy, short-course, a significant difference (p < 0.05. For the self administration of treatment strategy, the variables significantly associated with treatment noncompliance were as follows: being an unregistered worker (relative risk [RR] = 3.06; retreatment (RR = 2.73; alcoholism (RR = 3.10; and no investigation of contacts (RR = 8.94. For the directly observed therapy, short-course strategy, no variables were significantly associated with noncompliance. CONCLUSION: The directly observed therapy

  20. Administrative Aspects of Human Experimentation.

    Science.gov (United States)

    Irvine, George W.

    1992-01-01

    The following administrative aspects of scientific experimentation with human subjects are discussed: the definition of human experimentation; the distinction between experimentation and treatment; investigator responsibility; documentation; the elements and principles of informed consent; and the administrator's role in establishing and…

  1. Contact Center Manager Administration (CCMA)

    Data.gov (United States)

    Social Security Administration — CCMA is the server that provides a browser-based tool for contact center administrators and supervisors. It is used to manage and configure contact center resources...

  2. Opportunities for administrators to promote disease management.

    Science.gov (United States)

    Kash, Bita A; Gamm, Larry D; Bolin, Jane Nelson; Peck, B Mitchell

    2005-01-01

    Studies of disease management (DM) have shown that patients who participate in such programs achieve better health status and make fewer emergency room visits. Private and government payers have recently increased their efforts to promote DM initiatives through financial incentives to healthcare providers. This article explores opportunities for administrators of health services organizations (HSO) to promote DM in the current political and economic environment. Our survey of professionals (DM leaders, physicians, and DM nurses) in six DM programs reveals these professionals' assessments of the key players and resources that they deem important to their respective DM programs. They view DM programs as heavily dependent on the support of physicians, nurses, and health plan leaders but relatively less so on the support of HSO administrators- a situation that may suggest opportunities for administrators to take on greater leadership in moving the HSO toward developing DM programs. Survey results also indicate a strong need for the integration of resources such as communication systems, electronic medical records, and DM reporting. Taken collectively, these needs suggest a number of strategies for the administrator to play a larger role in supporting the adoption and effective implementation of DM. In the article, we propose that DM programs can benefit substantially from an administrator who can demonstrate a thorough knowledge of DM-related government and private-payer initiatives and who has the ability to provide leadership to develop and implement viable DM programs. Valued contributions that the administrator should bring to the table include support of standardized DM processes, use of practice guidelines, and provision of pertinent information systems.

  3. Export strategy

    DEFF Research Database (Denmark)

    Knudsen, Thorbjørn; Koed Madsen, Tage

    2002-01-01

    It is argued here that traditional export strategy research (encompassing the study of internationalization processes and export performance) is characterized by weak theoretical foundations and could benefit from a reorientation towards a dynamic capabilities perspective (DCP). We seek to draw...... on insights from DCP in order to devise a theoretical basis that could enrich export strategy research. Although our development of DCP insights builds on previous work, it also adds a crucial distinction between knowledge stocks and informational architecture. Changes in architecture are of greater...... importance. Following this elaboration of the dynamic capabilities perspective, we outline some implications and guidelines for future export strategy research....

  4. Environmental strategy

    DEFF Research Database (Denmark)

    Zabkar, Vesna; Cater, Tomaz; Bajde, Domen

    2013-01-01

    Environmental issues and the inclusion of environmental strategies in strategic thinking is an interesting subject of investigation. In general, managerial practices organized along ecologically sound principles contribute to a more environmentally sustainable global economy. From the managerial...... perspective, appropriate environmental strategies in compliance with environmental requirements aim at building competitive advantages through sustainable development. There is no universal “green” strategy that would be appropriate for each company, regardless of its market requirements and competitive...... situations. Instead, managers undertake careful consideration of the circumstances in which their company operates, paying special attention to their customers’ environmental preferences....

  5. Generation of pulsed ion beams by an inductive storage pulsed power generator

    Science.gov (United States)

    Katsuki, Sunao; Akiyama, Hidenori; Maeda, Sadao

    1990-10-01

    A pulsed power generator by an inductive energy storage system is extremely compact and light in comparison with a conventional pulsed power generator, which consists of a Marx bank and a water pulse forming line. A compact and light pulse power generator is applied to the generation of pulsed ion beams. A thin copper fuse is used an an opening switch, which is necessary in the inductive storage pulsed power generator. A magnetically insulated diode is used for the generation of ion beams. The pulsed ion beams are successfully generated by the inductive storage pulsed power generator for the first time.

  6. The interpretation of administrative contracts

    Directory of Open Access Journals (Sweden)

    Cătălin-Silviu SĂRARU

    2014-06-01

    Full Text Available The article analyzes the principles of interpretation for administrative contracts, in French law and in Romanian law. In the article are highlighted derogations from the rules of contract interpretation in common law. Are examined the exceptions to the principle of good faith, the principle of common intention (willingness of the parties, the principle of good administration, the principle of extensive interpretation of the administrative contract. The article highlights the importance and role of the interpretation in administrative contracts.

  7. 76 FR 64228 - Draft Guidance for Industry and Food and Drug Administration Staff; Class II Special Controls...

    Science.gov (United States)

    2011-10-17

    .... 76, No. 200 / Monday, October 17, 2011 / Notices#0;#0; ] DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration Draft Guidance for Industry and Food and Drug Administration Staff; Class II Special Controls Guidance Document: External Pacemaker Pulse Generator; Availability AGENCY: Food and...

  8. RBAC Administration in Distributed Systems

    NARCIS (Netherlands)

    Dekker, M.A.C.; Crampton, J.; Etalle, S.

    2007-01-01

    Despite a large body of literature on the administration of RBAC policies in centralized systems, the problem of the administration of a distributed system has hardly been addressed. We present a formal system for modelling a distributed RBAC system and its administration. We define two basic requir

  9. Certification of Financial Aid Administrators

    Science.gov (United States)

    Peterson, Stacey A.

    2011-01-01

    The certification of financial aid administrators has been debated for over 37 years. A job satisfaction survey conducted by the National Association of Student Financial Aid Administrators (NASFAA, 2008a) revealed that college and university administrators' perceptions of the efficiency, effectiveness, and quality of the services provided by the…

  10. Administration for Children and Families

    Science.gov (United States)

    ... Releases RSS Feeds Speeches Videos What is the Administration for Children & Families? The Administration for Children and Families (ACF) is a division ... Center Blog Press Releases RSS Feeds Speeches Videos Administration for Children & Families U.S. Department of Health & Human ...

  11. Control over Administrative Contract Formation

    Directory of Open Access Journals (Sweden)

    Frane Staničić

    2016-02-01

    Full Text Available Administrative contracts in Croatian legislation represent a novelty introduced into the General Administration Procedure Act in 2010. This is a novelty which has not proved to be successful in practice. Control over administrative contract formation is inevitable and is very significant for a number of reasons. Firstly, public legal bodies which form them do so by exercising their own public powers which are without doubt subject to legality control; secondly, in forming administrative contracts, public funds are used which must be controlled; thirdly, forming administrative contracts often touches on using public goods. Due to the restrictive interpretation of administrative contracts in Croatian legislation, this institute is indisputably only regulated in the General Taxation Act. However, for more than two decades contracts which satisfy all presumptions have existed in our law in order to be considered as administrative contracts. It is for this reason that control over contracts will be dealt with for contracts considered by the author to be administrative contracts. These are contracts on concessions and contracts on public procurement. How inadequate today’s regulation of control of administrative contract formation is will be demonstrated, particularly regarding contracts on concession and public procurement. Legislative changes will be proposed which should result in a more quality system of control over administrative contract formation. How control over administrative contract formation cannot be considered as separate from control over administrative contract execution will also be shown.

  12. Cetacean Strategies.

    Science.gov (United States)

    Gilliland, Denise DelGrosso

    1991-01-01

    Suggested are activities about whales for children in schools not near the ocean. Activities designed to pique students' interest in whales and to investigate the size, breathing, buoyancy, and feeding strategies of whales are discussed. (CW)

  13. Cylindrically Polarized Nondiffracting Optical Pulses

    CERN Document Server

    Ornigotti, Marco; Szameit, Alexander

    2016-01-01

    We extend the concept of radially and azimuthally polarized optical beams to the polychromatic domain by introducing cylindrically polarized nondiffracting optical pulses. In particular, we discuss in detail the case of cylindrically polarized X-waves, both in the paraxial and nonparaxial regime. The explicit expressions for the electric and magnetic fields of cylindrically polarized X-waves is also reported.

  14. Nonparametric estimation of ultrasound pulses

    DEFF Research Database (Denmark)

    Jensen, Jørgen Arendt; Leeman, Sidney

    1994-01-01

    An algorithm for nonparametric estimation of 1D ultrasound pulses in echo sequences from human tissues is derived. The technique is a variation of the homomorphic filtering technique using the real cepstrum, and the underlying basis of the method is explained. The algorithm exploits a priori...

  15. Wave equations for pulse propagation

    Science.gov (United States)

    Shore, B. W.

    1987-06-01

    Theoretical discussions of the propagation of pulses of laser radiation through atomic or molecular vapor rely on a number of traditional approximations for idealizing the radiation and the molecules, and for quantifying their mutual interaction by various equations of propagation (for the radiation) and excitation (for the molecules). In treating short-pulse phenomena it is essential to consider coherent excitation phenomena of the sort that is manifest in Rabi oscillations of atomic or molecular populations. Such processes are not adequately treated by rate equations for excitation nor by rate equations for radiation. As part of a more comprehensive treatment of the coupled equations that describe propagation of short pulses, this memo presents background discussion of the equations that describe the field. This memo discusses the origin, in Maxwell's equations, of the wave equation used in the description of pulse propagation. It notes the separation into lamellar and solenoidal (or longitudinal and transverse) and positive and negative frequency parts. It mentions the possibility of separating the polarization field into linear and nonlinear parts, in order to define a susceptibility or index of refraction and, from these, a phase and group velocity.

  16. All about Heart Rate (Pulse)

    Science.gov (United States)

    ... get a picture of your health. Learn more: Blood Pressure Vs. Heart Rate Target Heart Rate Arrhythmias (abnormal heart rhythms) This ... Healthy 6 What are the Symptoms of High Blood Pressure? 7 All About Heart Rate (Pulse) 8 Warning Signs of a Heart Attack ...

  17. Atomic collisions involving pulsed positrons

    DEFF Research Database (Denmark)

    Merrison, J. P.; Bluhme, H.; Field, D.

    2000-01-01

    Conventional slow positron beams have been widely and profitably used to study atomic collisions and have been instrumental in understanding the dynamics of ionization. The next generation of positron atomic collision studies are possible with the use of charged particle traps. Not only can large...... of accelerators for producing intense positron pulses will be discussed in the context of atomic physics experiments....

  18. Ptychographic reconstruction of attosecond pulses

    CERN Document Server

    Lucchini, M; Ludwig, A; Gallmann, L; Keller, U; Feurer, T

    2015-01-01

    We demonstrate a new attosecond pulse reconstruction modality which uses an algorithm that is derived from ptychography. In contrast to other methods, energy and delay sampling are not correlated, and as a result, the number of electron spectra to record is considerably smaller. Together with the robust algorithm, this leads to a more precise and fast convergence of the reconstruction.

  19. CSR Pulsed Switching Power Supplies

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    In 2001, CSR power supply system made a great progress. Three prototypes were designed for CSR quadruple and correct magnet. Three different companies provided the three prototypes, but the same circuit-chopper were employed. The simplified diagram is showed in Fig.1. All pulsed switching power supply prototypes were tested successfully before the end of 2001.

  20. Leadership strategies in healthcare.

    Science.gov (United States)

    Menaker, Ronald

    2009-01-01

    Healthcare is one of the largest and most important industries in the United States because it affects every individual in the nation. Numerous parties are stakeholders in healthcare, which contributes to the complexity of change efforts. Physicians and administrators play a significant role by providing direct care and influencing other decisions that impact the delivery of patient care. Success in the healthcare industry is influenced by numerous factors, some of which are controllable and others that are not. Understanding leadership and change management will be increasingly important to overcome resistance to change and to improve relationships, the core of leadership in an environment that will become more challenging. In what follows, different approaches to understanding leadership and change management are presented along with other leadership strategies to enhance the effectiveness of leaders. Raising leader awareness regarding transformational leadership behaviors and developing strategies to increase the use of these behaviors may be helpful to enhance organizational performance.

  1. Temporal resolution beyond the average pulse duration in shaped noisy-pulse transient absorption spectroscopy.

    Science.gov (United States)

    Meyer, Kristina; Müller, Niklas; Liu, Zuoye; Pfeifer, Thomas

    2016-12-20

    In time-resolved spectroscopy, it is a widespread belief that the temporal resolution is determined by the laser pulse duration. Recently, it was observed and shown that partially coherent laser pulses as they are provided by free-electron-laser (FEL) sources offer an alternative route to reach a temporal resolution below the average pulse duration. Here, we demonstrate the generation of partially coherent light in the laboratory like we observe it at FELs. We present the successful implementation of such statistically fluctuating pulses by using the pulse-shaping technique. These pulses exhibit an average pulse duration about 10 times larger than their bandwidth limit. The shaped pulses are then applied to transient-absorption measurements in the dye IR144. Despite the noisy characteristics of the laser pulses, features in the measured absorption spectra occurring on time scales much faster than the average pulse duration are resolved, thus proving the universality of the described noisy-pulse concept.

  2. Optimal control of anthracnose using mixed strategies.

    Science.gov (United States)

    Fotsa Mbogne, David Jaures; Thron, Christopher

    2015-11-01

    In this paper we propose and study a spatial diffusion model for the control of anthracnose disease in a bounded domain. The model is a generalization of the one previously developed in [15]. We use the model to simulate two different types of control strategies against anthracnose disease. Strategies that employ chemical fungicides are modeled using a continuous control function; while strategies that rely on cultivational practices (such as pruning and removal of mummified fruits) are modeled with a control function which is discrete in time (though not in space). For comparative purposes, we perform our analyses for a spatially-averaged model as well as the space-dependent diffusion model. Under weak smoothness conditions on parameters we demonstrate the well-posedness of both models by verifying existence and uniqueness of the solution for the growth inhibition rate for given initial conditions. We also show that the set [0, 1] is positively invariant. We first study control by impulsive strategies, then analyze the simultaneous use of mixed continuous and pulse strategies. In each case we specify a cost functional to be minimized, and we demonstrate the existence of optimal control strategies. In the case of pulse-only strategies, we provide explicit algorithms for finding the optimal control strategies for both the spatially-averaged model and the space-dependent model. We verify the algorithms for both models via simulation, and discuss properties of the optimal solutions. Copyright © 2015 Elsevier Inc. All rights reserved.

  3. Cryosurgery with pulsed electric fields.

    Science.gov (United States)

    Daniels, Charlotte S; Rubinsky, Boris

    2011-01-01

    This study explores the hypothesis that combining the minimally invasive surgical techniques of cryosurgery and pulsed electric fields will eliminate some of the major disadvantages of these techniques while retaining their advantages. Cryosurgery, tissue ablation by freezing, is a well-established minimally invasive surgical technique. One disadvantage of cryosurgery concerns the mechanism of cell death; cells at high subzero temperature on the outer rim of the frozen lesion can survive. Pulsed electric fields (PEF) are another minimally invasive surgical technique in which high strength and very rapid electric pulses are delivered across cells to permeabilize the cell membrane for applications such as gene delivery, electrochemotherapy and irreversible electroporation. The very short time scale of the electric pulses is disadvantageous because it does not facilitate real time control over the procedure. We hypothesize that applying the electric pulses during the cryosurgical procedure in such a way that the electric field vector is parallel to the heat flux vector will have the effect of confining the electric fields to the frozen/cold region of tissue, thereby ablating the cells that survive freezing while facilitating controlled use of the PEF in the cold confined region. A finite element analysis of the electric field and heat conduction equations during simultaneous tissue treatment with cryosurgery and PEF (cryosurgery/PEF) was used to study the effect of tissue freezing on electric fields. The study yielded motivating results. Because of decreased electrical conductivity in the frozen/cooled tissue, it experienced temperature induced magnified electric fields in comparison to PEF delivered to the unfrozen tissue control. This suggests that freezing/cooling confines and magnifies the electric fields to those regions; a targeting capability unattainable in traditional PEF. This analysis shows how temperature induced magnified and focused PEFs could be used to

  4. Cryosurgery with pulsed electric fields.

    Directory of Open Access Journals (Sweden)

    Charlotte S Daniels

    Full Text Available This study explores the hypothesis that combining the minimally invasive surgical techniques of cryosurgery and pulsed electric fields will eliminate some of the major disadvantages of these techniques while retaining their advantages. Cryosurgery, tissue ablation by freezing, is a well-established minimally invasive surgical technique. One disadvantage of cryosurgery concerns the mechanism of cell death; cells at high subzero temperature on the outer rim of the frozen lesion can survive. Pulsed electric fields (PEF are another minimally invasive surgical technique in which high strength and very rapid electric pulses are delivered across cells to permeabilize the cell membrane for applications such as gene delivery, electrochemotherapy and irreversible electroporation. The very short time scale of the electric pulses is disadvantageous because it does not facilitate real time control over the procedure. We hypothesize that applying the electric pulses during the cryosurgical procedure in such a way that the electric field vector is parallel to the heat flux vector will have the effect of confining the electric fields to the frozen/cold region of tissue, thereby ablating the cells that survive freezing while facilitating controlled use of the PEF in the cold confined region. A finite element analysis of the electric field and heat conduction equations during simultaneous tissue treatment with cryosurgery and PEF (cryosurgery/PEF was used to study the effect of tissue freezing on electric fields. The study yielded motivating results. Because of decreased electrical conductivity in the frozen/cooled tissue, it experienced temperature induced magnified electric fields in comparison to PEF delivered to the unfrozen tissue control. This suggests that freezing/cooling confines and magnifies the electric fields to those regions; a targeting capability unattainable in traditional PEF. This analysis shows how temperature induced magnified and focused

  5. Cryosurgery with Pulsed Electric Fields

    Science.gov (United States)

    Daniels, Charlotte S.; Rubinsky, Boris

    2011-01-01

    This study explores the hypothesis that combining the minimally invasive surgical techniques of cryosurgery and pulsed electric fields will eliminate some of the major disadvantages of these techniques while retaining their advantages. Cryosurgery, tissue ablation by freezing, is a well-established minimally invasive surgical technique. One disadvantage of cryosurgery concerns the mechanism of cell death; cells at high subzero temperature on the outer rim of the frozen lesion can survive. Pulsed electric fields (PEF) are another minimally invasive surgical technique in which high strength and very rapid electric pulses are delivered across cells to permeabilize the cell membrane for applications such as gene delivery, electrochemotherapy and irreversible electroporation. The very short time scale of the electric pulses is disadvantageous because it does not facilitate real time control over the procedure. We hypothesize that applying the electric pulses during the cryosurgical procedure in such a way that the electric field vector is parallel to the heat flux vector will have the effect of confining the electric fields to the frozen/cold region of tissue, thereby ablating the cells that survive freezing while facilitating controlled use of the PEF in the cold confined region. A finite element analysis of the electric field and heat conduction equations during simultaneous tissue treatment with cryosurgery and PEF (cryosurgery/PEF) was used to study the effect of tissue freezing on electric fields. The study yielded motivating results. Because of decreased electrical conductivity in the frozen/cooled tissue, it experienced temperature induced magnified electric fields in comparison to PEF delivered to the unfrozen tissue control. This suggests that freezing/cooling confines and magnifies the electric fields to those regions; a targeting capability unattainable in traditional PEF. This analysis shows how temperature induced magnified and focused PEFs could be used to

  6. Wave equations for pulse propagation

    Energy Technology Data Exchange (ETDEWEB)

    Shore, B.W.

    1987-06-24

    Theoretical discussions of the propagation of pulses of laser radiation through atomic or molecular vapor rely on a number of traditional approximations for idealizing the radiation and the molecules, and for quantifying their mutual interaction by various equations of propagation (for the radiation) and excitation (for the molecules). In treating short-pulse phenomena it is essential to consider coherent excitation phenomena of the sort that is manifest in Rabi oscillations of atomic or molecular populations. Such processes are not adequately treated by rate equations for excitation nor by rate equations for radiation. As part of a more comprehensive treatment of the coupled equations that describe propagation of short pulses, this memo presents background discussion of the equations that describe the field. This memo discusses the origin, in Maxwell's equations, of the wave equation used in the description of pulse propagation. It notes the separation into lamellar and solenoidal (or longitudinal and transverse) and positive and negative frequency parts. It mentions the possibility of separating the polarization field into linear and nonlinear parts, in order to define a susceptibility or index of refraction and, from these, a phase and group velocity. The memo discusses various ways of characterizing the polarization characteristics of plane waves, that is, of parameterizing a transverse unit vector, such as the Jones vector, the Stokes vector, and the Poincare sphere. It discusses the connection between macroscopically defined quantities, such as the intensity or, more generally, the Stokes parameters, and microscopic field amplitudes. The material presented here is a portion of a more extensive treatment of propagation to be presented separately. The equations presented here have been described in various books and articles. They are collected here as a summary and review of theory needed when treating pulse propagation.

  7. Fault-Protected Laser Diode Drivers for Improving the Performance and Lifetime of Multiple-Millisecond, Long-Pulse LDAs for NASA LIDAR Systems Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This SBIR project will develop and deliver revolutionary driver technology with intelligent fault protection for driving long-pulse (> 2msec), quasi-CW laser...

  8. Design and Fabrication of a Breadboard, Fully Conductively Cooled, 2-Micron, Pulsed Laser for the 3-D Winds Decadal Survey Mission Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Design and fabricate a space-qualifiable, fully conductively cooled, 2-micron pulsed laser breadboard meeting the projected 3-D Winds mission requirements. Utilize...

  9. IMPLEMENTATION OF ASSET MANAGEMENT IN ROAD ADMINISTRATION OF SLOVAK REPUBLIC

    Directory of Open Access Journals (Sweden)

    Ľubomír Pepucha

    2014-03-01

    Full Text Available The article presents basic principles and solutions for the application of Asset Management as part of road administration in Slovakia. It deals with application of Assets management methods and best practices of global trends in road maintenance, repair and rehabilitation strategies. An effective public Asset Management combines principles and strategies of asset management used in private sector with sound practices and methods proven to be applicable by public road administrator and his digital information systems. The under-funding of road management leads to development of tools and methods, which enable us to define criteria for establishing priorities for investments into road assets.

  10. Key Obama officials leave administration

    Science.gov (United States)

    Showstack, Randy

    2013-01-01

    Secretary of the Interior Ken Salazar is one of the latest members of the Obama administration to announce that he is leaving his position near the start of President Obama's second term in office. Salazar, who has served as interior secretary since January 2009, intends to leave the department by the end of March, the department noted on 16 January. Salazar joins a number of other key officials who are planning to leave the administration. They include Environmental Protection Agency administrator Lisa Jackson, National Oceanic and Atmospheric Administration administrator Jane Lubchenco, and U.S. Geological Survey director Marcia McNutt.

  11. Pulse frequency classification based on BP neural network

    Institute of Scientific and Technical Information of China (English)

    WANG Rui; WANG Xu; YANG Dan; FU Rong

    2006-01-01

    In Traditional Chinese Medicine (TCM), it is an important parameter of the clinic disease diagnosis to analysis the pulse frequency. This article accords to pulse eight major essentials to identify pulse type of the pulse frequency classification based on back-propagation neural networks (BPNN). The pulse frequency classification includes slow pulse, moderate pulse, rapid pulse etc. By feature parameter of the pulse frequency analysis research and establish to identify system of pulse frequency features. The pulse signal from detecting system extracts period, frequency etc feature parameter to compare with standard feature value of pulse type. The result shows that identify-rate attains 92.5% above.

  12. Codependency: management and administrative policy implications.

    Science.gov (United States)

    Sorrentino, E A

    1991-01-01

    Health care practitioners may exhibit behaviors that are considered dysfunctional for personal well-being. These behaviors, feelings, and thoughts could affect the manager-employee relations, as well as the implementation of patient care. This discussion focuses on the relevance of codependency in human resource management. Implications of codependency for organizational structure, standards of care, and managerial roles are pointed out. Specific strategies are outlined in recognizing manifestations of codependency. Finally, administrative interventions such as the Employee Assessment and Counseling Programs are suggested to prevent the negative outcomes of codependency which can affect job performance.

  13. Developing classification indices for Chinese pulse diagnosis

    CERN Document Server

    Shu, Jian-Jun

    2014-01-01

    Aim: To develop classification criteria for Chinese pulse diagnosis and to objectify the ancient diagnostic technique. Methods: Chinese pulse curves are treated as wave signals. Multidimensional variable analysis is performed to provide the best curve fit between the recorded Chinese pulse waveforms and the collective Gamma density functions. Results: Chinese pulses can be recognized quantitatively by the newly-developed four classification indices, that is, the wave length, the relative phase difference, the rate parameter, and the peak ratio. The new quantitative classification not only reduces the dependency of pulse diagnosis on Chinese physician's experience, but also is able to interpret pathological wrist-pulse waveforms more precisely. Conclusions: Traditionally, Chinese physicians use fingertips to feel the wrist-pulses of patients in order to determine their health conditions. The qualitative theory of the Chinese pulse diagnosis is based on the experience of Chinese physicians for thousands of year...

  14. Dispersion compensation in chirped pulse amplification systems

    Science.gov (United States)

    Bayramian, Andrew James; Molander, William A.

    2014-07-15

    A chirped pulse amplification system includes a laser source providing an input laser pulse along an optical path. The input laser pulse is characterized by a first temporal duration. The system also includes a multi-pass pulse stretcher disposed along the optical path. The multi-pass pulse stretcher includes a first set of mirrors operable to receive input light in a first plane and output light in a second plane parallel to the first plane and a first diffraction grating. The pulse stretcher also includes a second set of mirrors operable to receive light diffracted from the first diffraction grating and a second diffraction grating. The pulse stretcher further includes a reflective element operable to reflect light diffracted from the second diffraction grating. The system further includes an amplifier, a pulse compressor, and a passive dispersion compensator disposed along the optical path.

  15. Linear transformer driver for pulse generation

    Science.gov (United States)

    Kim, Alexander A; Mazarakis, Michael G; Sinebryukhov, Vadim A; Volkov, Sergey N; Kondratiev, Sergey S; Alexeenko, Vitaly M; Bayol, Frederic; Demol, Gauthier; Stygar, William A

    2015-04-07

    A linear transformer driver includes at least one ferrite ring positioned to accept a load. The linear transformer driver also includes a first power delivery module that includes a first charge storage devices and a first switch. The first power delivery module sends a first energy in the form of a first pulse to the load. The linear transformer driver also includes a second power delivery module including a second charge storage device and a second switch. The second power delivery module sends a second energy in the form of a second pulse to the load. The second pulse has a frequency that is approximately three times the frequency of the first pulse. The at least one ferrite ring is positioned to force the first pulse and the second pulse to the load by temporarily isolating the first pulse and the second pulse from an electrical ground.

  16. Exact Solutions to Short Pulse Equation

    Institute of Scientific and Technical Information of China (English)

    FU Zun-Tao; ZHENG Ming-Hua; LIU Shi-Kuo

    2009-01-01

    In this paper, dependent and independent variable transformations are introduced to solve the short pulse equation. It is shown that different kinds of solutions can be obtained to the short pulse equation.

  17. Digital Communication Using Chaotic Pulse Generators

    CERN Document Server

    Rulkov, N F; Tsimring, L S; Volkovskii, A R; Abarbanel, Henry D I; Larson, L; Yao, K

    1999-01-01

    Utilization of chaotic signals for covert communications remains a very promising practical application. Multiple studies indicated that the major shortcoming of recently proposed chaos-based communication schemes is their susceptibility to noise and distortions in communication channels. In this talk we discuss a new approach to communication with chaotic signals, which demonstrates good performance in the presence of channel distortions. This communication scheme is based upon chaotic signals in the form of pulse trains where intervals between the pulses are determined by chaotic dynamics of a pulse generator. The pulse train with chaotic interpulse intervals is used as a carrier. Binary information is modulated onto this carrier by the pulse position modulation method, such that each pulse is either left unchanged or delayed by a certain time, depending on whether ``0'' or ``1'' is transmitted. By synchronizing the receiver to the chaotic pulse train we can anticipate the timing of pulses corresponding to ...

  18. Linear transformer driver for pulse generation

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Alexander A; Mazarakis, Michael G; Sinebryukhov, Vadim A; Volkov, Sergey N; Kondratiev, Sergey S; Alexeenko, Vitaly M; Bayol, Frederic; Demol, Gauthier; Stygar, William A

    2015-04-07

    A linear transformer driver includes at least one ferrite ring positioned to accept a load. The linear transformer driver also includes a first power delivery module that includes a first charge storage devices and a first switch. The first power delivery module sends a first energy in the form of a first pulse to the load. The linear transformer driver also includes a second power delivery module including a second charge storage device and a second switch. The second power delivery module sends a second energy in the form of a second pulse to the load. The second pulse has a frequency that is approximately three times the frequency of the first pulse. The at least one ferrite ring is positioned to force the first pulse and the second pulse to the load by temporarily isolating the first pulse and the second pulse from an electrical ground.

  19. Treatment Pulse Application for Magnetic Stimulation

    Directory of Open Access Journals (Sweden)

    Sun-Seob Choi

    2011-01-01

    Full Text Available Treatment and diagnosis can be made in difficult areas simply by changing the output pulse form of the magnetic stimulation device. However, there is a limitation in the range of treatments and diagnoses of a conventional sinusoidal stimulation treatment pulse because the intensity, width, and form of the pulse must be changed according to the lesion type. This paper reports a multidischarge method, where the stimulation coils were driven in sequence via multiple switching control. The limitation of the existing simple sinusoidal pulse form could be overcome by changing the intensity, width, and form of the pulse. In this study, a new sequential discharge method was proposed to freely alter the pulse width. The output characteristics of the stimulation treatment pulse were examined according to the trigger signal delay applied to the switch at each stage by applying a range of superposition pulses to the magnetic simulation device, which is widely used in industry and medicine.

  20. UML IN BUSINESS ADMINISTRATION

    Directory of Open Access Journals (Sweden)

    Daniel Ionita

    2010-12-01

    Full Text Available The article elaborates weather UML, primarily used in software engineering, can be a useful tool in business modeling and administration. By analyzing the advantages the modeling language has to offer we find that UML is visual and object oriented and that it is useful in expressing structure, interaction and behavior as well. With its help managers and business people can build models and diagrams to help put things into perspective. “Case Study 1” shows UML can be used as an analysis tool in business modeling to help increase the complexity and depth of the event or project that is being developed. “Case Study 2” attempts to prove that UML can also be efficiently used in finding solutions to newly appeared problems in a business environment. Despite the practicality of the Unified Modeling Language there is still some criticism brought to it. Some programmers consider it to be hard to learn and some developers claim that it is too abstract. The article concludes that despite the minor drawbacks; due to its adaptability and complex visual models, it is a very useful tool that adds value to the modeling of business structures and processes.