Ocular pulse amplitude after panretinal photocoagulation in normotensive eyes with proliferative diabetic retinopathy.

Science.gov (United States)

Bozic, Marija M; Karadzic, Jelena B; Kovacevic, Igor M; Marjanovic, Ivan S

2017-06-26

To assess the effect of panretinal laser photocoagulation on ocular pulse amplitude (OPA) in normotensive eyes with proliferative diabetic retinopathy. Prospectively, we performed unilateral argon laser panretinal photocoagulation (PRP) in 30 patients with diabetes mellitus type II and previously untreated bilateral proliferative diabetic retinopathy. Before and 7 and 30 days after the treatment, OPA was measured using dynamic contour tonometer. Compared with the untreated contralateral eyes, laser photocoagulation led to a reduction of OPA. Ocular pulse amplitude did not significantly differ in photocoagulated eyes 7 days after the treatment, but there was a significant difference in OPA 30 days after the treatment. The decrease in OPA values was 15% 7 days after PRP and 40% 30 days after PRP. Ocular pulse amplitude reduction after PRP indirectly informs us about choriocapillary closure, already reported in previous studies.

Amplitude and phase control of attosecond light pulses

International Nuclear Information System (INIS)

Lopez-Martens, Rodrigo; Varju, Katalin; Johnsson, Per; Mauritsson, Johan; Persson, Anders; Svanberg, Sune; Wahlstroem, Claes-Goeran; L'Huillier, Anne; Mairesse, Yann; Salieres, Pascal; Gaarde, Mette B.; Schafer, Kenneth J.

2005-01-01

We report the generation, compression, and delivery on target of ultrashort extreme-ultraviolet light pulses using external amplitude and phase control. Broadband harmonic radiation is first generated by focusing an infrared laser with a carefully chosen intensity into a gas cell containing argon atoms. The emitted light then goes through a hard aperture and a thin aluminum filter that selects a 30-eV bandwidth around a 30-eV photon energy and synchronizes all of the components, thereby enabling the formation of a train of almost Fourier-transform-limited single-cycle 170 attosecond pulses. Our experiment demonstrates a practical method for synthesizing and controlling attosecond waveforms

Intraocular pressure and ocular pulse amplitude using dynamic contour tonometry and contact lens tonometry.

Science.gov (United States)

Hoffmann, Esther M; Grus, Franz-H; Pfeiffer, Norbert

2004-03-23

The new Ocular Dynamic Contour Tonometer (DCT), investigational device supplied by SMT (Swiss Microtechnology AG, Switzerland) allows simultaneous recording of intraocular pressure (IOP) and ocular pulse amplitude (OPA). It was the aim of this study to compare the IOP results of this new device with Goldmann tonometry. Furthermore, IOP and OPA measured with the new slitlamp-mounted DCT were compared to the IOP and OPA measured with the hand-held SmartLens,a gonioscopic contact lens tonometer (ODC Ophthalmic Development Company AG, Switzerland). Nineteen healthy subjects were included in this study. IOP was determined by three consecutive measurements with each of the DCT, SmartLens, and Goldmann tonometer. Furthermore, OPA was measured three times consecutively by DCT and SmartLens. No difference (P = 0.09) was found between the IOP values by means of DCT (mean: 16.6 mm Hg, median: 15.33 mm Hg, SD: +/- 4.04 mm Hg) and Goldmann tonometry (mean: 16.17 mm Hg, median: 15.33 mm Hg, SD: +/- 4.03 mm Hg). The IOP values of SmartLens (mean: 20.25 mm Hg, median: 19.00 mm Hg, SD: +/- 4.96 mm Hg) were significantly higher (P = 0.0008) both from Goldmann tonometry and DCT. The OPA values of the DCT (mean: 3.08 mm Hg, SD: +/- 0.92 mm Hg) were significantly lower (P = 0.0003) than those obtained by SmartLens (mean: 3.92 mm Hg, SD: +/- 0.83 mm Hg). DCT was equivalent to Goldmann applanation tonometry in measurement of IOP in a small group of normal subjects. In contrast, SmartLens (contact lens tonometry) gave IOP readings that were significantly higher compared with Goldmann applanation tonometer readings. Both devices, DCT and SmartLens provide the measurement of OPA which could be helpful e.g. for the management of glaucoma.

Numerical calculation of spin echo amplitude in pulsed NMR: effects of quadrupole interaction

International Nuclear Information System (INIS)

Sobral, R.R.

1986-01-01

The spin echo obtained by nuclear magnetic resonance, in systems which atomic nuclei interact with magnetic fields and electric field gradients, present oscillations in function of the time interval between two excitations pulses. Using the density matrix formalism, the amplitudes of these echo is calculated, analytically. In this work, echo amplitudes obtained under different excitation conditions for nuclei of different nuclear spin values are calculated. The numerical results are compared with disposable analytical solutions. Applications of this method to the case of electric field gradient without axial symmetry were studied. Within the used approximation limits, an expression for attnuation of oscillatory behaviour of echo amplitude in function of the time interval between experimentally observed pulses was obtained. (M.C.K.) [pt

The effect of positive end-expiratory pressure on pulse pressure ...

African Journals Online (AJOL)

The effect of positive end-expiratory pressure on pulse pressure variation. FJ Smith, M Geyser, I Schreuder, PJ Becker. Abstract. Objectives: To determine the effect of different levels of positive end-expiratory pressure (PEEP) on pulse pressure variation (PPV). Design: An observational study. Setting: Operating theatres of a ...

A nuclear pulse amplitude acquisition system based on 80C31 single-chip microcomputer

International Nuclear Information System (INIS)

Zhao Xiuliang; Qu Guopu; Guo Lanying; Zhang Songbai

1999-01-01

A kind of multichannel nuclear pulse amplitude signal acquisition system is described, which is composed of pulse peak detector, integrated S/H circuit, A/D converter and 80C31 single-chip microcomputer

Pulse pressure and diabetes treatments: Blood pressure and pulse pressure difference among glucose lowering modality groups in type 2 diabetes.

Science.gov (United States)

Alemi, Hamid; Khaloo, Pegah; Mansournia, Mohammad Ali; Rabizadeh, Soghra; Salehi, Salome Sadat; Mirmiranpour, Hossein; Meftah, Neda; Esteghamati, Alireza; Nakhjavani, Manouchehr

2018-02-01

Type 2 diabetes is associated with higher pulse pressure. In this study, we assessed and compared effects of classic diabetes treatments on pulse pressure (PP), systolic blood pressure (SBP), and diastolic blood pressure (DBP) in patients with type 2 diabetes.In a retrospective cohort study, 718 non-hypertensive patients with type 2 diabetes were selected and divided into 4 groups including metformin, insulin, glibenclamide+metformin, and metformin+insulin. They were followed for 4 consecutive visits lasting about 45.5 months. Effects of drug regimens on pulse and blood pressure over time were assessed separately and compared in regression models with generalized estimating equation method and were adjusted for age, duration of diabetes, sex, smoking, and body mass index (BMI).Studied groups had no significant change in PP, SBP, and DBP over time. No significant difference in PP and DBP among studied groups was observed (PP:P = 0.090; DBP:P = 0.063). Pairwise comparisons of PP, SBP, and DBP showed no statistically significant contrast between any 2 studied groups. Interactions of time and treatment were not different among groups.Our results demonstrate patients using metformin got higher PP and SBP over time. Averagely, pulse and blood pressure among groups were not different. Trends of variation in pulse and blood pressure were not different among studied diabetes treatments.

Studies on gas breakdown in pulsed radio frequency atmospheric pressure glow discharges

International Nuclear Information System (INIS)

Huo, W. G.; Jian, S. J.; Yao, J.; Ding, Z. F.

2014-01-01

In pulsed RF atmospheric pressure glow discharges, the gas breakdown judged by the rapid drop in the amplitude of the pulsed RF voltage is no longer universally true. The steep increment of the plasma-absorbed RF power is proposed to determine the gas breakdown. The averaged plasma-absorbed RF power over a pulse period is used to evaluate effects of the preceding pulsed RF discharge on the breakdown voltage of the following one, finding that the breakdown voltage decreases with the increment in the averaged plasma-absorbed RF power under constant pulse duty ratio. Effects of the pulse off-time on the breakdown voltage and the breakdown delay time are also studied. The obtained dependence of the breakdown voltage on the pulse off-time is indicative of the transitional plasma diffusion processes in the afterglow. The breakdown voltage varies rapidly as the plasma diffuses fast in the region of moderate pulse off-time. The contribution of nitrogen atom recombination at the alumina surface is demonstrated in the prolonged memory effect on the breakdown delay time vs. the pulse off-time and experimentally validated by introducing a trace amount of nitrogen into argon at short and long pulse off-times

Pulse-amplitude multipliers using logarithmic amplitude-to-time conversion; Amplificateurs d'impulsions utilisant une conversion logarithmique temps-amplitude; Ob umnozhitelyakh amplitudy impul'sov s ispol'zovaniem logarifmicheskogo preobrazovaniya amplitudy vo vremya; Multiplicadores de amplitud de impulso usando una conversion logaritmica de amplitud en tiempo

Energy Technology Data Exchange (ETDEWEB)

Konrad, M [Institut Rudjer Boskovic, Zagreb, Yugoslavia (Croatia)

1962-04-15

The accuracy and limitations of multipliers based on logarithmic amplitude-to-time conversion using RC pulse stretchers are discussed with respect to their application for determining whether the amplitude product of two coincident pulses has a given value. Some possible circuits are given. (author) [French] L'auteur etudie la precision et les limitations des amplificateurs fondes sur la conversion logarithmique temps-amplitude et utilisant des allongeurs d'impulsions RC, afin d'etablir si ces appareils peuvent servir a determiner la valeur du produit des amplitudes de deux impulsions coincidentes. Il decrit en outre plusieurs circuits possibles. (author) [Spanish] La memoria discute la precision y limitaciones de los multiplicadores basados en la conversion logaritmica de amplitud en tiempo empleando circuitos alargadores de resistencia-capacidad en relacion con su aplicacion para determinar si el producto de las amplitudes de dos impulsos coincidentes tiene un valor determinado. Indica algunos circuitos posibles. (author) [Russian] Obsuzhdayutsya predel pogreshnosti i ogranicheniya umnozhitelej, osnovannykh na logarifmicheskom preobrazovanii amplitudy vo vremya, s ispol'zovaniem rasshiritelej impul'sov RC; ehto delaetsya v svyazi s ikh primeneniem dlya vyyasneniya voprosa o tom, imeet li opredelennuyu velichinu proizvedenie amplitud dvukh sovpadayushchikh impul'sov. Privodyatsya nekotorye vozmozhnye blok-skhemy. (author)

Pulse Rise Time Characterization of a High Pressure Xenon Gamma Detector for use in Resolution Enhancement

CERN Document Server

Troyer, G L

2000-01-01

High pressure xenon ionization chamber detectors are possible alternatives to traditional thallium doped sodium iodide (NaI(Tl)) and hyperpure germanium as gamma spectrometers in certain applications. Xenon detectors incorporating a Frisch grid exhibit energy resolutions comparable to cadmium/zinc/telluride (CZT) (e.g. 2% (at) 662keV) but with far greater sensitive volumes. The Frisch grid reduces the position dependence of the anode pulse risetimes, but it also increases the detector vibration sensitivity, anode capacitance, voltage requirements and mechanical complexity. We have been investigating the possibility of eliminating the grid electrode in high-pressure xenon detectors and preserving the high energy resolution using electronic risetime compensation methods. A two-electrode cylindrical high pressure xenon gamma detector coupled to time-to-amplitude conversion electronics was used to characterize the pulse rise time of deposited gamma photons. Time discrimination was used to characterize the pulse r...

Intraocular pressure and ocular pulse amplitude using dynamic contour tonometry and contact lens tonometry

Directory of Open Access Journals (Sweden)

Grus Franz-H

2004-03-01

Full Text Available Abstract Background The new Ocular Dynamic Contour Tonometer (DCT, investigational device supplied by SMT (Swiss Microtechnology AG, Switzerland allows simultaneous recording of intraocular pressure (IOP and ocular pulse amplitude (OPA. It was the aim of this study to compare the IOP results of this new device with Goldmann tonometry. Furthermore, IOP and OPA measured with the new slitlamp-mounted DCT were compared to the IOP and OPA measured with the hand-held SmartLens®, a gonioscopic contact lens tonometer (ODC Ophthalmic Development Company AG, Switzerland. Methods Nineteen healthy subjects were included in this study. IOP was determined by three consecutive measurements with each of the DCT, SmartLens®, and Goldmann tonometer. Furthermore, OPA was measured three times consecutively by DCT and SmartLens®. Results No difference (P = 0.09 was found between the IOP values by means of DCT (mean: 16.6 mm Hg, median: 15.33 mm Hg, SD: +/- 4.04 mm Hg and Goldmann tonometry (mean: 16.17 mm Hg, median: 15.33 mm Hg, SD: +/- 4.03 mm Hg. The IOP values of SmartLens® (mean: 20.25 mm Hg, median: 19.00 mm Hg, SD: +/- 4.96 mm Hg were significantly higher (P = 0.0008 both from Goldmann tonometry and DCT. The OPA values of the DCT (mean: 3.08 mm Hg, SD: +/- 0.92 mm Hg were significantly lower (P = 0.0003 than those obtained by SmartLens® (mean: 3.92 mm Hg, SD: +/- 0.83 mm Hg. Conclusions DCT was equivalent to Goldmann applanation tonometry in measurement of IOP in a small group of normal subjects. In contrast, SmartLens® (contact lens tonometry gave IOP readings that were significantly higher compared with Goldmann applanation tonometer readings. Both devices, DCT and SmartLens® provide the measurement of OPA which could be helpful e.g. for the management of glaucoma.

A New Selective Harmonic Elimination Pulse- Width and Amplitude Modulation (SHEPWAM) for Drive Applications

DEFF Research Database (Denmark)

Ghoreishy, Hoda; Varjani, Ali Yazdian; Mohamadian, Mustafa

2013-01-01

Compared to the conventional selective harmonic elimination-pulse width modulation (SHE-PWM), the selective harmonic elimination-pulse width and amplitude modulation (SHE-PWAM) control strategy results in significant improvements in the performance of CHB inverters. This fact is due to considerin...

Generator of pulses with the nanosecond duration and accurate amplitude using the digital control in the CAMAC standard

International Nuclear Information System (INIS)

Basiladze, S.G.; Nguen Kuang Min'

1980-01-01

A generator of square-wave fine-amplitude nanosecond pulses is described. The generator is primarily intended for checking the performances of fast electronics analog-to-digital units with the help of a computer. In addition to digital control the pulse amplitude can be controlled manually or by the external voltage. Basic circuits of main generator assemblies: a triggering circuit, transistor key and digital-to-analog converter are given. Output pulses produced by the generator have the following parameters: the amplitude from - 0.15 to - 10 V (smooth or gradual, with a minimum step of 5 mV), the rising and decay pulse times approximately 2 ns, the maximum repetition frequency 10 kHz, the control linearity at a pulse duration of more than 50 ns 0.15%. A double-width CAMAC cell accomodates two generators

Pulse Rise Time Characterization of a High Pressure Xenon Gamma Detector for use in Resolution Enhancement

International Nuclear Information System (INIS)

TROYER, G.L.

2000-01-01

High pressure xenon ionization chamber detectors are possible alternatives to traditional thallium doped sodium iodide (NaI(Tl)) and hyperpure germanium as gamma spectrometers in certain applications. Xenon detectors incorporating a Frisch grid exhibit energy resolutions comparable to cadmium/zinc/telluride (CZT) (e.g. 2% (at) 662keV) but with far greater sensitive volumes. The Frisch grid reduces the position dependence of the anode pulse risetimes, but it also increases the detector vibration sensitivity, anode capacitance, voltage requirements and mechanical complexity. We have been investigating the possibility of eliminating the grid electrode in high-pressure xenon detectors and preserving the high energy resolution using electronic risetime compensation methods. A two-electrode cylindrical high pressure xenon gamma detector coupled to time-to-amplitude conversion electronics was used to characterize the pulse rise time of deposited gamma photons. Time discrimination was used to characterize the pulse rise time versus photo peak position and resolution. These data were collected to investigate the effect of pulse rise time compensation on resolution and efficiency

An experimental investigation on the pressure characteristics of high speed self-resonating pulsed waterjets influenced by feeding pipe diameter

Energy Technology Data Exchange (ETDEWEB)

Li, Dong; Kang, Dong; Ding, Xiao Long; Wang, Xiao Huan; Fang, Zhen Long [School of Power and Mechanical Engineering, Wuhan University, Hubei Province (China)

2016-11-15

The destructive power of a continuous waterjet issuing from a nozzle can be greatly enhanced by generating self-resonance in the nozzle assembly to produce a Self-resonating pulsed waterjet (SRPW). To further improve the performance of SRPW, effects of feeding pipe diameter on the pressure characteristics were experimentally investigated by measuring and analyzing the axial pressure oscillation peaks and amplitudes. Four organ-pipe nozzles of different chamber lengths and three feeding pipes of different diameters were employed. Results show that feeding pipe diameter cannot change the feature of SRPW of having an optimum standoff distance, but it slightly changes the oscillating frequency of the jet. It is also found that feeding pipe diameter significantly affects the magnitudes of pressure oscillation peak and amplitude, largely depending on the pump pressure and standoff distance. The enhancement or attenuation of the pressure oscillation peak and amplitude can be differently affected by the same feeding pipe diameter.

The neuronal response to electrical constant-amplitude pulse train stimulation: additive Gaussian noise.

Science.gov (United States)

Matsuoka, A J; Abbas, P J; Rubinstein, J T; Miller, C A

2000-11-01

Experimental results from humans and animals show that electrically evoked compound action potential (EAP) responses to constant-amplitude pulse train stimulation can demonstrate an alternating pattern, due to the combined effects of highly synchronized responses to electrical stimulation and refractory effects (Wilson et al., 1994). One way to improve signal representation is to reduce the level of across-fiber synchrony and hence, the level of the amplitude alternation. To accomplish this goal, we have examined EAP responses in the presence of Gaussian noise added to the pulse train stimulus. Addition of Gaussian noise at a level approximately -30 dB relative to EAP threshold to the pulse trains decreased the amount of alternation, indicating that stochastic resonance may be induced in the auditory nerve. The use of some type of conditioning stimulus such as Gaussian noise may provide a more 'normal' neural response pattern.

A high-resolution two-pulse coherent anti-Stokes Raman scattering spectrum using a spectral amplitude modulation

International Nuclear Information System (INIS)

Lu, Chenhui; Zhang, Shian; Wu, Meizhen; Jia, Tianqing; Sun, Zhenrong; Qiu, Jianrong

2013-01-01

Femtosecond coherent anti-Stokes Raman scattering (CARS) spectra suffer from low spectral resolution because of the broadband laser spectrum. In this paper, we propose a feasible scheme to achieve a high-resolution two-pulse CARS spectrum by shaping both the pump and probe pulses using rectangular amplitude modulation. We show that a narrowband hole in the CARS spectrum can be created by the amplitude-shaped laser pulse, the position of which is correlated with the Raman resonant frequency of the molecule. Thus, by observing holes in the CARS spectrum, we are able to obtain a high-resolution CARS spectrum and the energy-level diagram of the molecule. (paper)

Practical use of the amplitude and phase modulation of a high-power RF pulse via feed-forward control

International Nuclear Information System (INIS)

Kawase, Keigo; Kato, Ryukou; Irizawa, Akinori; Isoyama, Goro; Kashiwagi, Shigeru

2013-01-01

A new feed-forward control system to precisely control the amplitude and phase of the pulsed RF power in an electron linear accelerator (linac) is developed to make the accelerating field constant. Fast variations and ripples in the amplitude and phase in the RF pulses are compensated by modulating the amplitude and phase in the low-level system with a variable attenuator and phase shifter. The system is innovated the overdrive technique, which is commonly used in analog circuits, to speed up the slow response of the phase shifter, while the control signals are digitally processed; thus, the method is a hybrid of analog and digital techniques. By using the new control system, we find that the peak-to-peak variations in the amplitude and phase are reduced from 11.6% to 0.4% and from 6.1 degrees to 0.3 degrees, respectively, in 7.6-μs-long RF pulses for the L-band electron linac at Osaka University. (author)

Analog Amplitude Modulation of a High Voltage, Solid State Inductive Adder, Pulse Generator Using MOSFETS

International Nuclear Information System (INIS)

Gower, E J; Sullivan, J S

2002-01-01

High voltage, solid state, inductive adder, pulse generators have found increasing application as fast kicker pulse modulators for charged particle beams. The solid state, inductive adder, pulse generator is similar in operation to the linear induction accelerator. The main difference is that the solid state, adder couples energy by transformer action from multiple primaries to a voltage summing stalk, instead of an electron beam. Ideally, the inductive adder produces a rectangular voltage pulse at the load. In reality, there is usually some voltage variation at the load due to droop on primary circuit storage capacitors, or, temporal variations in the load impedance. Power MOSFET circuits have been developed to provide analog modulation of the output voltage amplitude of a solid state, inductive adder, pulse generator. The modulation is achieved by including MOSFET based, variable subtraction circuits in the multiple primary stack. The subtraction circuits can be used to compensate for voltage droop, or, to tailor the output pulse amplitude to provide a desired effect in the load. Power MOSFET subtraction circuits have been developed to modulate short, temporal (60-400 ns), voltage and current pulses. MOSFET devices have been tested up to 20 amps and 800 Volts with a band pass of 50 MHz. An analog modulation cell has been tested in a five cell high, voltage adder stack

Can the use of pulsed direct current induce oscillation in the applied pressure during spark plasma sintering?

International Nuclear Information System (INIS)

Salamon, David; Eriksson, Mirva; Nygren, Mats; Shen Zhijian

2012-01-01

The spark plasma sintering (SPS) process is known for its rapid densification of metals and ceramics. The mechanism behind this rapid densification has been discussed during the last few decades and is yet uncertain. During our SPS experiments we noticed oscillations in the applied pressure, related to a change in electric current. In this study, we investigated the effect of pulsed electrical current on the applied mechanical pressure and related changes in temperature. We eliminated the effect of sample shrinkage in the SPS setup and used a transparent quartz die allowing direct observation of the sample. We found that the use of pulsed direct electric current in our apparatus induces pressure oscillations with the amplitude depending on the current density. While sintering Ti samples we observed temperature oscillations resulting from pressure oscillations, which we attribute to magnetic forces generated within the SPS apparatus. The described current–pressure–temperature relations might increase understanding of the SPS process.

The design of multi-channel pulse amplitude analyzer based on ARM micro controller

International Nuclear Information System (INIS)

Li Hai; Li Xiang; Liu Caixue

2010-01-01

It introduces the design of multi-channel pulse amplitude analyzer based on embedded ARM micro-controller. The embedded and real-time system μC/OS-II builds up the real-time and stability of the system and advances the integration. (authors)

Measuring sub-bandage pressure: comparing the use of pressure monitors and pulse oximeters.

Science.gov (United States)

Satpathy, A; Hayes, S; Dodds, S R

2006-03-01

To test the use of low-cost sub-bandage pressure monitors and pulse oximeters as part of a quality-control measure for graduated compression bandaging in leg ulcer clinics. Twenty-five healthy volunteers (mean age 40 years) providing 50 limbs were bandaged with a four-layer compression bandaging system. The ankle systolic pressure (ASP) was measured using a pulse oximeter (Nellcor NBP-40) before applying the graduated compression bandages. Interface pressure was measured by placing pressure sensors on the skin at three points (2cm above the medial malleolus; the widest part of the calf; and a point midway between them) in the supine and standing positions. The ASP was measured again with the pulse oximeter after the bandage had been applied, and the effect of the bandage on the ASP was recorded. The actual pressure created by the bandage was compared with the required pressure profile. Interface pressures varied with change of position and movement. With the operator blinded to the pressure monitors while applying the bandages, the target pressure of 35-40mmHg at the ankle was achieved in only 36% of limbs ([mean +/- 95% confidence interval]; 32.3 +/- 1.6mmHg [supine]; 38.4 +/- 2.4mmHg [standing position]). With the help of the pressure monitors, the target pressure was achieved in 78% of the limbs. There was no correlation between the pressure monitors and pulse oximeter pressures, demonstrating that the pulse oximeter is not a useful tool for measuring sub-bandage pressures. The results suggest a tool (interface pressure monitors) that is easy to operate should be available as part of quality assurance for treatment, training of care providers and education.

Cognitive-Behavioral Therapy versus Temporal Pulse Amplitude Biofeedback Training for Recurrent Headache

Science.gov (United States)

Martin, Paul R.; Forsyth, Michael R.; Reece, John

2007-01-01

Sixty-four headache sufferers were allocated randomly to cognitive-behavioral therapy (CBT), temporal pulse amplitude (TPA) biofeedback training, or waiting-list control. Fifty-one participants (14M/37F) completed the study, 30 with migraine and 21 with tension-type headache. Treatment consisted of 8, 1-hour sessions. CBT was highly effective,…

Available pressure amplitude of linear compressor based on phasor triangle model

Science.gov (United States)

Duan, C. X.; Jiang, X.; Zhi, X. Q.; You, X. K.; Qiu, L. M.

2017-12-01

The linear compressor for cryocoolers possess the advantages of long-life operation, high efficiency, low vibration and compact structure. It is significant to study the match mechanisms between the compressor and the cold finger, which determines the working efficiency of the cryocooler. However, the output characteristics of linear compressor are complicated since it is affected by many interacting parameters. The existing matching methods are simplified and mainly focus on the compressor efficiency and output acoustic power, while neglecting the important output parameter of pressure amplitude. In this study, a phasor triangle model basing on analyzing the forces of the piston is proposed. It can be used to predict not only the output acoustic power, the efficiency, but also the pressure amplitude of the linear compressor. Calculated results agree well with the measurement results of the experiment. By this phasor triangle model, the theoretical maximum output pressure amplitude of the linear compressor can be calculated simply based on a known charging pressure and operating frequency. Compared with the mechanical and electrical model of the linear compressor, the new model can provide an intuitionistic understanding on the match mechanism with faster computational process. The model can also explain the experimental phenomenon of the proportional relationship between the output pressure amplitude and the piston displacement in experiments. By further model analysis, such phenomenon is confirmed as an expression of the unmatched design of the compressor. The phasor triangle model may provide an alternative method for the compressor design and matching with the cold finger.

Pulsed laser manipulation of an optically trapped bead: Averaging thermal noise and measuring the pulsed force amplitude

DEFF Research Database (Denmark)

Lindballe, Thue Bjerring; Kristensen, Martin V. G.; Keiding, Søren Rud

2013-01-01

An experimental strategy for post-eliminating thermal noise on position measurements of optically trapped particles is presented. Using a nanosecond pulsed laser, synchronized to the detection system, to exert a periodic driving force on an optically trapped 10 polystyrene bead, the laser pulse-bead...... interaction is repeated hundreds of times. Traces with the bead position following the prompt displacement from equilibrium, induced by each laser pulse, are averaged and reveal the underlying deterministic motion of the bead, which is not visible in a single trace due to thermal noise. The motion of the bead...... is analyzed from the direct time-dependent position measurements and from the power spectrum. The results show that the bead is on average displaced 208 nm from the trap center and exposed to a force amplitude of 71 nanoNewton, more than five orders of magnitude larger than the trapping forces. Our...

Telemetry Standards, RCC Standard 106-17, Annex A.1, Pulse Amplitude Modulation Standards

Science.gov (United States)

2017-07-01

Standard 106-17 Annex A.1, July 2017 A.1-iii Acronyms dB decibel FM frequency modulation IF intermediate frequency PAM pulse amplitude...premodulation filter when employed. b. One-fifth of the intermediate frequency (IF) bandwidth (3 dB points) selected from the IF bandwidths listed in

Suppression of acoustic streaming in tapered pulse tubes

International Nuclear Information System (INIS)

Olson, J.R.; Swift, G.W.

1998-01-01

In a pulse tube cryocooler, the gas in the pulse tube can be thought of as an insulating piston, transmitting pressure and velocity from the cold heat exchanger to the hot end of the pulse tube. Unfortunately, convective heat transfer can carry heat from the hot end to the cold end and reduce the net cooling power. Here, the authors discuss one driver of such convection: steady acoustic streaming as generated by interactions between the boundary and the oscillating pressure, velocity, and temperature. Using a perturbation method, they have derived an analytical expression for the streaming in a tapered pulse tube with axially varying mean temperature in the acoustic boundary layer limit. The calculations showed that the streaming depends strongly on the taper angle, the ratio of velocity and pressure amplitudes, and the phase between the velocity and pressure, but it depends only weakly on the mean temperature profile and is independent of the overall oscillatory amplitude. With the appropriate tapering of the tube, streaming can be eliminated for a particular operating condition. Experimentally, the authors have demonstrated that an orifice pulse tube cryocooler with the calculated zero-streaming taper has more cooling power than one with either a cylindrical tube or a tapered pulse tube with twice the optimum taper angle

Pulse-amplitude modulation of optical injection-locked quantum-dot lasers

Science.gov (United States)

Zhou, Yue-Guang; Wang, Cheng

2018-02-01

This work theoretically investigates the four-level pulse-amplitude modulation characteristics of quantum dot lasers subject to optical injection. The rate equation model takes into account carrier dynamics in the carrier reservoir, in the excited state, and in the ground state, as well as photon dynamics and phase dynamics of the electric field. It is found that the optical injection significantly improves the eye diagram quality through suppressing the relaxation oscillation, while the extinction ratio is reduced as well. In addition, both the adiabatic chirp and the transient chirp of the signal are substantially suppressed.

Tensile Strength of Water Exposed to Pressure Pulses

DEFF Research Database (Denmark)

Andersen, Anders Peter; Mørch, Knud Aage

2012-01-01

at an extended water-solid interface by imposing a tensile stress pulse which easily causes cavitation. Next, a compressive pulse of duration ~1 ms and a peak intensity of a few bar is imposed prior to the tensile stress pulse. A dramatic increase of the tensile strength is observed immediately after......It is well known that pressurization for an extended period of time increases the tensile strength of water, but little information is available on the effect of pressure pulses of short duration. This is addressed in the present paper where we first measure the tensile strength of water...

Changes in mean plasma ACTH reflect changes in amplitude and frequency of secretory pulses

International Nuclear Information System (INIS)

Carnes, M.; Lent, S.J.; Erisman, S.; Feyzi, J.

1988-01-01

ACTH is secreted in an episodic manner from the anterior pituitary. Unanesthetized rats with indwelling jugular and femoral venous cannulae were continuously bled and simultaneously infused with isotonic fluid by peristaltic pump. Two-minute blood samples were collected for up to five hours in 8 male rats. ACTH was measured by radioimmunoassay. The resulting time series were analyzed for significant secretory pulses with the PULSAR program. Elevations or declines in mean plasma ACTH levels were associated with significant changes in amplitude and frequency of secretory pulses

Numerical simulation of the pressure pulses produced by a pressure screen foil rotor

International Nuclear Information System (INIS)

Feng, M.; Ollivier-Gooch, C.; Gooding, R.W.; Olson, J.A.

2003-01-01

Pressure screening is the most industrially efficient and effective means of removing contaminants that degrade the appearance and strength of paper and fractionating fibres for selective treatments and specialty products. A critical design component of a screen is the rotor which produces pressure pulses on the screen cylinder surface to keep the screening apertures clear. To understand the effect of the key design and operating variables for a NACA 0012 foil rotor, a computational fluid dynamic (CFD) simulation tool was developed with FLUENT software, and the numerical results were compared with experimental measurements. The computational results of pressure pulses were shown to be in good agreement with experimental pressure measurements over a wide range of foil tip-speeds, clearances and angles of attack. In addition, it was shown that the magnitude of the pressure pulse peak increases as the rotating speed increases linearly with the square of tip-speed for all the angles of attack studied. The maximum negative pressure pulse occurred for the foil at 5 degrees angle of attack. Flow began to separate from foil surface near the screen plate beyond 10 degrees angle of attack. The positive pressure peak near the leading edge of the foil is completely eliminated for foils operating at a positive angle of attack. The magnitude of the negative pressure peak increased as clearance decreased. In addition to, and more important than, these specific results, we have shown that CFD is a viable tool for the optimal design and operation of rotors in industrial pressure screens. (author)

Pulsed pressure treatment for inactivation of escherichia coli and listeria innocua in whole milk

Energy Technology Data Exchange (ETDEWEB)

Buzrul, S; Largeteau, A; Demazeau, G [ICMCB, CNRS, Universite Bordeaux 1, site de l' ENSCPB, 87 avenue du Dr. A. Schweitzer, 33608 PESSAC cedex (France); Alpas, H [Food Engineering Department, Middle East Technical University, 06531, Ankara (Turkey)], E-mail: sbuzrul@metu.edu.tr

2008-07-15

E. coli and L. innocua in whole milk were subjected to continuous pressure treatments (300, 350, 400, 450, 500, 550 and 600 MPa) at ambient temperature for 5, 10, 15 and 20 min. These treatments underlined that at moderate pressure values (300, 350 and 400 MPa), increasing the pressurization time from 5 to 20 min did not improve cell death to a great extent. Therefore, pulsed pressure treatments (at 300, 350 and 400 MPa) for 5 min (2.5 min x 2 pulses, 1 min x 5 pulses and 0.5 min x 10 pulses), 10 min (5 min x 2 pulses, 2 min x 5 pulses and 1 min x 10 pulses), 15 min (5 min x 3 pulses, 3 min x 5 pulses and 1.5 min x 10 pulses) and 20 min (10 min x 2 pulses, 5 min x 4 pulses, 4 min x 5 pulses and 2 min x 10 pulses) were applied. As already observed in continuous pressure experiments, in pulsed pressure treatments the inactivation level is improved with increasing pressure level and in addition with the number of applied pulses; however, the effect of pulse number is not additive. Results obtained in this study indicated that pulsed pressure treatments could be used to pasteurize the whole milk at lower pressure values than the continuous pressure treatments. Nevertheless, an optimization appears definetely necessary between the number of pulses and pressure levels to reach the desirable number of log-reduction of microorganisms.

Pulsed pressure treatment for inactivation of escherichia coli and listeria innocua in whole milk

Science.gov (United States)

Buzrul, S.; Largeteau, A.; Alpas, H.; Demazeau, G.

2008-07-01

E. coli and L. innocua in whole milk were subjected to continuous pressure treatments (300, 350, 400, 450, 500, 550 and 600 MPa) at ambient temperature for 5, 10, 15 and 20 min. These treatments underlined that at moderate pressure values (300, 350 and 400 MPa), increasing the pressurization time from 5 to 20 min did not improve cell death to a great extent. Therefore, pulsed pressure treatments (at 300, 350 and 400 MPa) for 5 min (2.5 min × 2 pulses, 1 min × 5 pulses and 0.5 min × 10 pulses), 10 min (5 min × 2 pulses, 2 min × 5 pulses and 1 min × 10 pulses), 15 min (5 min × 3 pulses, 3 min × 5 pulses and 1.5 min × 10 pulses) and 20 min (10 min × 2 pulses, 5 min × 4 pulses, 4 min × 5 pulses and 2 min × 10 pulses) were applied. As already observed in continuous pressure experiments, in pulsed pressure treatments the inactivation level is improved with increasing pressure level and in addition with the number of applied pulses; however, the effect of pulse number is not additive. Results obtained in this study indicated that pulsed pressure treatments could be used to pasteurize the whole milk at lower pressure values than the continuous pressure treatments. Nevertheless, an optimization appears definetely necessary between the number of pulses and pressure levels to reach the desirable number of log-reduction of microorganisms.

Pulsed pressure treatment for inactivation of escherichia coli and listeria innocua in whole milk

International Nuclear Information System (INIS)

Buzrul, S; Largeteau, A; Demazeau, G; Alpas, H

2008-01-01

E. coli and L. innocua in whole milk were subjected to continuous pressure treatments (300, 350, 400, 450, 500, 550 and 600 MPa) at ambient temperature for 5, 10, 15 and 20 min. These treatments underlined that at moderate pressure values (300, 350 and 400 MPa), increasing the pressurization time from 5 to 20 min did not improve cell death to a great extent. Therefore, pulsed pressure treatments (at 300, 350 and 400 MPa) for 5 min (2.5 min x 2 pulses, 1 min x 5 pulses and 0.5 min x 10 pulses), 10 min (5 min x 2 pulses, 2 min x 5 pulses and 1 min x 10 pulses), 15 min (5 min x 3 pulses, 3 min x 5 pulses and 1.5 min x 10 pulses) and 20 min (10 min x 2 pulses, 5 min x 4 pulses, 4 min x 5 pulses and 2 min x 10 pulses) were applied. As already observed in continuous pressure experiments, in pulsed pressure treatments the inactivation level is improved with increasing pressure level and in addition with the number of applied pulses; however, the effect of pulse number is not additive. Results obtained in this study indicated that pulsed pressure treatments could be used to pasteurize the whole milk at lower pressure values than the continuous pressure treatments. Nevertheless, an optimization appears definetely necessary between the number of pulses and pressure levels to reach the desirable number of log-reduction of microorganisms

High amplitude ultrasound pulse generation using time-reversal through a multiple scattering medium

OpenAIRE

ARNAL , Bastien; Pernot , Mathieu; Fink , Mathias; Tanter , Mickaël

2012-01-01

International audience; In histotripsy, soft tissues can be fragmented using very high pressure ultrasound pulses. Using time-reversal cavity is a way to generate high pressure pulses with a limited number of acoustic sources. The principle was already demonstrated by Montaldo et al. using a solid metal cavity, but low transmission coefficient was obtained due to the strong impedance mismatch at the metal/water interface. We propose here to use a waveguide filled with water containing a 2D mu...

Large amplitude dynamics of micro-/nanomechanical resonators actuated with electrostatic pulses

International Nuclear Information System (INIS)

Juillard, J.; Bonnoit, A.; Avignon, E.; Hentz, S.; Colinet, E.

2010-01-01

In the field of resonant nano-electro-mechanical system (NEMS) design, it is a common misconception that large-amplitude motion, and thus large signal-to-noise ratio, can only be achieved at the risk of oscillator instability. In the present paper, we show that very simple closed-loop control schemes can be used to achieve stable large-amplitude motion of a resonant structure even when jump resonance (caused by electrostatic softening or Duffing hardening) is present in its frequency response. We focus on the case of a resonant accelerometer sensing cell, consisting of a nonlinear clamped-clamped beam with electrostatic actuation and detection, maintained in an oscillation state with pulses of electrostatic force that are delivered whenever the detected signal (the position of the beam) crosses zero. We show that the proposed feedback scheme ensures the stability of the motion of the beam much beyond the critical Duffing amplitude and that, if the parameters of the beam are correctly chosen, one can achieve almost full-gap travel range without incurring electrostatic pull-in. These results are illustrated and validated with transient simulations of the nonlinear closed-loop system.

Differential Amplitude Pulse-Position Modulation for Indoor Wireless Optical Communications

Directory of Open Access Journals (Sweden)

Sethakaset Ubolthip

2005-01-01

Full Text Available We propose a novel differential amplitude pulse-position modulation (DAPPM for indoor optical wireless communications. DAPPM yields advantages over PPM, DPPM, and DH-PIM in terms of bandwidth requirements, capacity, and peak-to-average power ratio (PAPR. The performance of a DAPPM system with an unequalized receiver is examined over nondispersive and dispersive channels. DAPPM can provide better bandwidth and/or power efficiency than PAM, PPM, DPPM, and DH-PIM depending on the number of amplitude levels and the maximum length of a symbol. We also show that, given the same maximum length, DAPPM has better bandwidth efficiency but requires about and more power than PPM and DPPM, respectively, at high bit rates over a dispersive channel. Conversely, DAPPM requires less power than DH-PIM . When the number of bits per symbol is the same, PAM requires more power, and DH-PIM less power, than DAPPM. Finally, it is shown that the performance of DAPPM can be improved with MLSD, chip-rate DFE, and multichip-rate DFE.

Pulse testing in the presence of wellbore storage and skin effects

Energy Technology Data Exchange (ETDEWEB)

Ogbe, D.O.; Brigham, W.E.

1984-08-01

A pulse test is conducted by creating a series of short-time pressure transients in an active (pulsing) well and recording the observed pressure response at an observation (responding) well. Using the pressure response and flow rate data, the transmissivity and storativity of the tested formation can be determined. Like any other pressure transient data, the pulse-test response is significantly influenced by wellbore storage and skin effects. The purpose of this research is to examine the influence of wellbore storage and skin effects on interference testing in general and on pulse-testing in particular, and to present the type curves and procedures for designing and analyzing pulse-test data when wellbore storage and skin effects are active at either the responding well or the pulsing well. A mathematical model for interference testing was developed by solving the diffusivity equation for radial flow of a single-phase, slightly compressible fluid in an infinitely large, homogeneous reservoir. When wellbore storage and skin effects are present in a pulse test, the observed response amplitude is attenuated and the time lag is inflated. Consequently, neglecting wellbore storage and skin effects in a pulse test causes the calculated storativity to be over-estimated and the transmissivity to be under-estimated. The error can be as high as 30%. New correlations and procedures are developed for correcting the pulse response amplitude and time lag for wellbore storage effects. Using these correlations, it is possible to correct the wellbore storage-dominated response amplitude and time lag to within 3% of their expected values without wellbore storage, and in turn to calculate the corresponding transmissivity and storativity. Worked examples are presented to illustrate how to use the new correction techniques. 45 references.

Pulse Pressure: An Indicator of Heart Health?

Science.gov (United States)

... pressure should also be considered alongside pulse pressure values. Higher systolic and diastolic pairs imply higher risk than ... endorse any of the third party products and services advertised. Advertising ... Education and Research. © 1998-2018 Mayo Foundation for Medical ...

Models of brachial to finger pulse wave distortion and pressure decrement.

Science.gov (United States)

Gizdulich, P; Prentza, A; Wesseling, K H

1997-03-01

To model the pulse wave distortion and pressure decrement occurring between brachial and finger arteries. Distortion reversion and decrement correction were also our aims. Brachial artery pressure was recorded intra-arterially and finger pressure was recorded non-invasively by the Finapres technique in 53 adult human subjects. Mean pressure was subtracted from each pressure waveform and Fourier analysis applied to the pulsations. A distortion model was estimated for each subject and averaged over the group. The average inverse model was applied to the full finger pressure waveform. The pressure decrement was modelled by multiple regression on finger systolic and diastolic levels. Waveform distortion could be described by a general, frequency dependent model having a resonance at 7.3 Hz. The general inverse model has an anti-resonance at this frequency. It converts finger to brachial pulsations thereby reducing average waveform distortion from 9.7 (s.d. 3.2) mmHg per sample for the finger pulse to 3.7 (1.7) mmHg for the converted pulse. Systolic and diastolic level differences between finger and brachial arterial pressures changed from -4 (15) and -8 (11) to +8 (14) and +8 (12) mmHg, respectively, after inverse modelling, with pulse pressures correct on average. The pressure decrement model reduced both the mean and the standard deviation of systolic and diastolic level differences to 0 (13) and 0 (8) mmHg. Diastolic differences were thus reduced most. Brachial to finger pulse wave distortion due to wave reflection in arteries is almost identical in all subjects and can be modelled by a single resonance. The pressure decrement due to flow in arteries is greatest for high pulse pressures superimposed on low means.

Digital pulse processing techniques for high resolution amplitude measurement of radiation detector

International Nuclear Information System (INIS)

Singhai, P.; Roy, A.; Dhara, P.; Chatterjee, S.

2012-01-01

The digital pulse processing techniques for high resolution amplitude measurement of radiation detector pulse is an effective replacement of expensive and bulky analog processing as the digital domain offers higher channel density and at the same time it is cheaper. We have demonstrated a prototype digital setup with highspeed sampling ADC with sampling frequency of 80-125 MHz followed by series of IIR filters for pulse shaping in a trigger-less acquisition mode. The IIR filters, peak detection algorithm and the data write-out logic was written on VHDL and implemented on FPGA. We used CAMAC as the read out platform. In conjunction with the full hardware implementation we also used a mixed platform with VME digitizer card with raw-sample read out using C code. The rationale behind this mixed platform is to test out various filter algorithms quickly on C and also to benchmark the performance of the chip level ADCs against the standard commercial digitizer in terms of noise or resolution. The paper describes implementation of both the methods with performance obtained in both the methods. (author)

Parametric Study of Pulse-Combustor-Driven Ejectors at High-Pressure

Science.gov (United States)

Yungster, Shaye; Paxson, Daniel E.; Perkins, Hugh D.

2015-01-01

Pulse-combustor configurations developed in recent studies have demonstrated performance levels at high-pressure operating conditions comparable to those observed at atmospheric conditions. However, problems related to the way fuel was being distributed within the pulse combustor were still limiting performance. In the first part of this study, new configurations are investigated computationally aimed at improving the fuel distribution and performance of the pulse-combustor. Subsequent sections investigate the performance of various pulse-combustor driven ejector configurations operating at highpressure conditions, focusing on the effects of fuel equivalence ratio and ejector throat area. The goal is to design pulse-combustor-ejector configurations that maximize pressure gain while achieving a thermal environment acceptable to a turbine, and at the same time maintain acceptable levels of NOx emissions and flow non-uniformities. The computations presented here have demonstrated pressure gains of up to 2.8%.

Monitoring of deposits in pipelines using pressure pulse technology

Energy Technology Data Exchange (ETDEWEB)

Gudmundsson, Jon S.; Celius, Harald K.

2005-07-01

The basis of pressure pulse technology is presented in terms of the water hammer equation, the pipeline pressure drop equation and the equation for speed of sound in multiphase mixtures. The technology can be used for a range of applications, from on-line monitoring of flowing conditions to on-demand measurements and analysis to locate and quantify deposits in wells and pipelines. While pressure pulse measurements are low-cost and easy to implement, the commercial use of pressure pulse technology has resulted from extensive field experience and substantial in-house software development. Simulation tools were used to illustrate the effect of a 2 mm thick deposit, 500 m long and located 375 m from a quick-acting valve. The simulation conditions used are typical for multiphase gas-oil flow along a horizontal 2 km long pipeline from wellhead to manifold. (Author)

Method of summation of amplitudes of coinciding pulses from Ge(Li) detectors used to study cascades of gamma-transitions in (n,#betta#) reaction

International Nuclear Information System (INIS)

Bogdzel', A.A.; Vasil'eva, Eh.V.; Elizarov, O.I.

1982-01-01

Main performanes and peculiarities of spectrometer based on the coincidence pulse amplitude total-count method and containing two Ge(La) detectors with transmission neutron spectrometer - IBR-30 pulse reactor are considered. It is shown on the 35 Cl(n, #betta#) reaction that the method of summalion of amplitudes of coinciding pulses from the Ge(Li) detector can be used to study the cascades of two #betta#-transitions with a total energy similar to the neutron binding energy. The shape of the response function of this spectrometer was studied versus the energies of #betta#-transition cascades

The pulsed amplitude unit for the SLC

International Nuclear Information System (INIS)

Rolfe, J.; Browne, M.J.; Jobe, R.K.

1987-02-01

There is a recurring requirement in the SLC for the control of devices such as magnets, phase shifters, and attenuators on a beam-by-beam basis. The Pulsed Amplitude Unit (PAU) is a single width CAMAC module developed for this purpose. It provides digitally programmed analog output voltages on a beam-by-beam basis. Up to 32 preprogrammed values of output voltage are available from the single analog output of the module, and any of these values can be associated with any of the 256 possible SLC beam definitions. A 12-bit Analog-to-Digital Converter (ADC) digitizes an analog input signal at the appropriate beam time and stores it in a buffer memory. This feature is normally used to monitor the response of the device being controlled by the PAU at each beam time. Initial application of the PAU is a part of the system that controls the output of Klystrons in the SLC. The PAU combines several different functions in a single module. In order to accommodate these functions in a single width CAMAC module, field programmed logic is used extensively. Field Programmable Logic Arrays, Programmed Array Logic, and a Field Programmable Logic Sequencer are employed

The pulsed amplitude unit for the SLC

International Nuclear Information System (INIS)

Rolfe, J.; Browne, M.J.; Jobe, R.K.

1987-01-01

There is a recurring requirement in the SLC for the control of devices such as magnets, phase shifters, and attenuators on a beam-by-beam basis. The Pulsed Amplitude Unit (PAU) is a single width CAMAC module developed for this purpose. It provides digitally programmed analog output voltages on a beam-by-beam basis. Up to 32 preprogrammed values of output voltage are available from the single analog output of the module, and any of these values can be associated with any of the 256 possible SLC beam definitions. A 12-bit Analog-to-Digital converter (ADC) digitizes an analog input signal at the appropriate beam time and stores it in a buffer memory. This feature is normally used to monitor the response of the device being controlled by the PAU at each beam time. Initial application of the PAU at is as part of the system that controls the output of Klystorns in the SLC. The PAU combines several different functions in a single module. In order to accommodate these functions in a single width CAMAC module, field programmed logic is used extensively. Field Programmable Logic Arrays, Programmed Array Logic, and a Field Programmable Logic Sequencer are employed

Pressure pulses generated by gas released from a breached fuel element

International Nuclear Information System (INIS)

Wu, T.S.

1979-01-01

In experimental measurements of liquid pressure pulses generated by rapid release of gas from breached fuel elements in a nuclear reactor, different peak pressures were observed at locations equidistant from the origin of the release. Using the model of a submerged spherical bubble with a nonstationary center, this analysis predicts not only that the peak pressure would be higher at a point in front of the advancing bubble than that at a point the same distance behind the bubble origin, but also that the pressure pulse in front of the bubble reaches its peak later than the pulse behind the origin

Effects of large pressure amplitude low frequency noise in the parotid gland perivasculo-ductal connective tissue.

Science.gov (United States)

Oliveira, Pedro; Brito, José; Mendes, João; da Fonseca, Jorge; Águas, Artur; Martins dos Santos, José

2013-01-01

In tissues and organs exposed to large pressure amplitude low frequency noise fibrosis occurs in the absence of inflammatory signs, which is thought to be a protective response. In the parotid gland the perivasculo-ductal connective tissue surrounds arteries, veins and the ductal tree. Perivasculo-ductal connective tissue is believed to function as a mechanical stabilizer of the glandular tissue. In order to quantify the proliferation of perivasculo-ductal connective tissue in large pressure amplitude low frequency noise-exposed rats we used sixty Wistar rats which were equally divided into 6 groups. One group kept in silence, and the remaining five exposed to continuous large pressure amplitude low frequency noise: g1-168h (1 week); g2-504h (3 weeks); g3-840h (5 weeks); g4-1512h (9 weeks); and g5-2184h (13 weeks). After exposure, parotid glands were removed and the perivasculo-ductal connective tissue area was measured in all groups. We applied ANOVA statistical analysis, using SPSS 13.0. The global trend is an increase in the average perivasculo-ductal connective tissue areas, that develops linearly and significantly with large pressure amplitude low frequency noise exposure time (p connective tissue. Hence, these results show that in response to large pressure amplitude low frequency noise exposure, rat parotid glands increase their perivasculo-ductal connective tissue.

An evaluation of the effects of eyeball structure on ocular pulse amplitude in healthy subjects.

Science.gov (United States)

Ishii, Kotaro; Mori, Mikiro; Oshika, Tetsuro

2012-12-01

To evaluate the effects of eyeball structure on ocular pulse amplitude (OPA) measured using dynamic contour tonometer (DCT). In 86 eyes of 43 healthy subjects, we measured OPA and intraocular pressure (IOP) with DCT (DCT-IOP), IOP with Goldmann applanation tonometry (GAT-IOP), central corneal thickness (CCT), corneal thickness 2 mm (2 mmCT) and 4 mm (4 mmCT) apart from the center, corneal volume within a 3.5-mm radius from the corneal center, corneal curvature, anterior chamber depth, anterior chamber volume, and axial length (AL). OPA had a significant positive correlation with GAT-IOP (Pearson's r = 0.412, p < 0.001), DCT-IOP (r = 0.350, p < 0.001), and 4 mmCT (r = 0.244, p = 0.0231), and had a significant negative correlation with AL (r = -0.268, p = 0.0122). In a multiple linear regression analysis, AL and GAT-IOP were significantly associated with OPA. OPA measured with DCT is significantly influenced by several factors, such as IOP, peripheral corneal thickness (4 mmCT), and AL.

Effect of pulse pressure on borehole stability during shear swirling flow vibration cementing.

Directory of Open Access Journals (Sweden)

Zhihua Cui

Full Text Available The shear swirling flow vibration cementing (SSFVC technique rotates the downhole eccentric cascade by circulating cementing fluid. It makes the casing eccentrically revolve at high speed around the borehole axis. It produces strong agitation action to the annulus fluid, makes it in the state of shear turbulent flow, and results in the formation of pulse pressure which affects the surrounding rock stress. This study was focused on 1 the calculation of the pulse pressure in an annular turbulent flow field based on the finite volume method, and 2 the analysis of the effect of pulse pressure on borehole stability. On the upside, the pulse pressure is conducive to enhancing the liquidity of the annulus fluid, reducing the fluid gel strength, and preventing the formation of fluid from channeling. But greater pulse pressure may cause lost circulation and even formation fracturing. Therefore, in order to ensure smooth cementing during SSFVC, the effect of pulse pressure should be considered when cementing design.

Investigation of a mutual interaction force at different pressure amplitudes in sulfuric acid

International Nuclear Information System (INIS)

Rezaee, Nastaran; Sadighi-Bonabi, Rasoul; Mirheydari, Mona; Ebrahimi, Homa

2011-01-01

This paper investigates the secondary Bjerknes force for two oscillating bubbles in various pressure amplitudes in a concentration of 95% sulfuric acid. The equilibrium radii of the bubbles are assumed to be smaller than 10 μm at a frequency of 37 kHz in various strong driving acoustical fields around 2.0 bars (1 bar=10 5 Pa). The secondary Bjerknes force is investigated in uncoupled and coupled states between the bubbles, with regard to the quasi-adiabatic model for the bubble interior. It finds that the value of the secondary Bjerknes force depends on the driven pressure of sulfuric acid and its amount would be increased by liquid pressure amplitude enhancement. The results show that the repulsion area of the interaction force would be increased by increasing the driven pressure because of nonlinear oscillation of bubbles. (condensed matter: electronic structure, electrical, magnetic, and optical properties)

Generation of runaway electron beams in high-pressure nitrogen

Science.gov (United States)

Tarasenko, V. F.; Burachenko, A. G.; Baksht, E. Kh

2017-07-01

In this paper the results of experimental studies of the amplitude-temporal characteristics of a runaway electron beam, as well as breakdown voltage in nitrogen are presented. The voltage pulses with the amplitude in incident wave ≈120 kV and the rise time of ≈0.3 ns was used. The supershort avalanche electron beam (SAEB) was detected by a collector behind the flat anode. The amplitude-time characteristics of the voltage and SAEB current were studied with subnanosecond time resolution. The maximum pressure at which a SAEB is detectable by collector was ∼1 MPa. This pressure increases with decreasing the voltage rise time. The waveforms of the discharge and runaway electron beam currents was synchronized with the voltage pulses. The mechanism of the runaway electron generation in atmospheric-pressure gases is analyzed on the basis of the obtained experimental data.

Pressure heat pumping in the orifice pulse-tube refrigerator

International Nuclear Information System (INIS)

Boer, P.C.T. de

1996-01-01

The mechanism by which heat is pumped as a result of pressure changes in an orifice pulse-tube refrigerator (OPTR) is analyzed thermodynamically. The thermodynamic cycle considered consists of four steps: (1) the pressure is increased by a factor π 1 due to motion of a piston in the heat exchanger at the warm end of the regenerator; (2) the pressure is decreased by a factor π 2 due to leakage out of the orifice; (3) the pressure is further decreased due to motion of the piston back to its original position; (4) the pressure is increased to its value at the start of the cycle due to leakage through the orifice back into the pulse tube. The regenerator and the heat exchangers are taken to be perfect. The pressure is assumed to be uniform during the entire cycle. The temperature profiles of the gas in the pulse tube after each step are derived analytically. Knowledge of the temperature at which gas enters the cold heat exchanger during steps 3 and 4 provides the heat removed per cycle from this exchanger. Knowledge of the pressure as a function of piston position provides the work done per cycle by the piston. The pressure heat pumping mechanism considered is effective only in the presence of a regenerator. Detailed results are presented for the heat removed per cycle, for the coefficient of performance, and for the refrigeration efficiency as a function of the compression ratio π 1 and the expansion ratio π 2 . Results are also given for the influence on performance of the ratio of specific heats. The results obtained are compared with corresponding results for the basic pulse-tube refrigerator (BPTR) operating by surface heat pumping

Comparison of under-pressure and over-pressure pulse tests conducted in low-permeability basalt horizons at the Hanford Site, Washington State

International Nuclear Information System (INIS)

Thorne, P.D.; Spane, F.A. Jr.

1984-10-01

Over-pressure pulse tests (pressurized slug tests have been widely used by others for hydraulic characterization of low-permeability ( -8 m/sec) rock formations. Recent field studies of low-permeability basalt horizons at the Hanford Site, Washington, indicate that the under-pressure pulse technique is also a viable test method for hydraulic characterization studies. For over-pressure pulse tests, fluid within the test system is rapidly pressurized and the associated pressure decay is monitored as compressed fluid within the test system expands and flows into the test formation. Under-pressure pulse tests are conducted in a similar manner by abruptly decreasing the pressure of fluid within the test system, and monitoring the associated increase in pressure as fluid flows from the formation into the test system. Both pulse test methods have been used in conjunction with other types of tests to determine the hydraulic properties of selected low-permeability basalt horizons at Hanford test sites. Results from both pulse test methods generally provide comparable estimates of hydraulic properties and are in good agreement with those from other tests

Efficient amplitude-modulated pulses for triple- to single-quantum coherence conversion in MQMAS NMR.

Science.gov (United States)

Colaux, Henri; Dawson, Daniel M; Ashbrook, Sharon E

2014-08-07

The conversion between multiple- and single-quantum coherences is integral to many nuclear magnetic resonance (NMR) experiments of quadrupolar nuclei. This conversion is relatively inefficient when effected by a single pulse, and many composite pulse schemes have been developed to improve this efficiency. To provide the maximum improvement, such schemes typically require time-consuming experimental optimization. Here, we demonstrate an approach for generating amplitude-modulated pulses to enhance the efficiency of the triple- to single-quantum conversion. The optimization is performed using the SIMPSON and MATLAB packages and results in efficient pulses that can be used without experimental reoptimisation. Most significant signal enhancements are obtained when good estimates of the inherent radio-frequency nutation rate and the magnitude of the quadrupolar coupling are used as input to the optimization, but the pulses appear robust to reasonable variations in either parameter, producing significant enhancements compared to a single-pulse conversion, and also comparable or improved efficiency over other commonly used approaches. In all cases, the ease of implementation of our method is advantageous, particularly for cases with low sensitivity, where the improvement is most needed (e.g., low gyromagnetic ratio or high quadrupolar coupling). Our approach offers the potential to routinely improve the sensitivity of high-resolution NMR spectra of nuclei and systems that would, perhaps, otherwise be deemed "too challenging".

Numerical Solution of the Kzk Equation for Pulsed Finite Amplitude Sound Beams in Thermoviscous Fluids

Science.gov (United States)

Lee, Yang-Sub

A time-domain numerical algorithm for solving the KZK (Khokhlov-Zabolotskaya-Kuznetsov) nonlinear parabolic wave equation is developed for pulsed, axisymmetric, finite amplitude sound beams in thermoviscous fluids. The KZK equation accounts for the combined effects of diffraction, absorption, and nonlinearity at the same order of approximation. The accuracy of the algorithm is established via comparison with analytical solutions for several limiting cases, and with numerical results obtained from a widely used algorithm for solving the KZK equation in the frequency domain. The time domain algorithm is used to investigate waveform distortion and shock formation in directive sound beams radiated by pulsed circular piston sources. New results include predictions for the entire process of self-demodulation, and for the effect of frequency modulation on pulse envelope distortion. Numerical results are compared with measurements, and focused sources are investigated briefly.

Ankle Blood Pressure and Pulse Pressure as Predictors of Cerebrovascular Morbidity and Mortality in a Prospective Follow-Up Study

Directory of Open Access Journals (Sweden)

Heikki J. Hietanen

2010-01-01

Full Text Available Background and Objective. We examined the association of elevated ankle blood pressure (ABP, together with exercise blood pressure, with incident cerebrovascular (CV morbidity and mortality in a prospective follow-up study of 3,808 patients. The results were compared with pulse pressure, another indicator of arterial stiffness. Methods. Patients with normal ankle and exercise brachial blood pressures were taken as the reference group. Pulse pressure was considered as quartiles with the lowest quartile as the reference category. Results. A total of 170 subjects had a CV event during the follow-up. Multivariate adjusted hazard ratio of a CV event was 2.24 (95% CI 1.43–3.52, <.0001 in patients with abnormal ABP. The pulse pressure was significant only in the model adjusted for age and sex. Conclusion. The risk of a future CV event was elevated already in those patients among whom elevated ABP was the only abnormal finding. As a risk marker, ABP is superior to the pulse pressure.

Pulse pressure and diurnal blood pressure variation

DEFF Research Database (Denmark)

Knudsen, Søren Tang; Poulsen, Per Løgstrup; Hansen, Klavs Würgler

2002-01-01

retinopathy, nephropathy, macrovascular disease, PP, and diurnal BP variation in a group of type 2 diabetic patients. METHODS: In 80 type 2 diabetic patients we performed 24-h ambulatory BP (AMBP) and fundus photographs. Urinary albumin excretion was evaluated by urinary albumin/creatinine ratio. Presence...... or absence of macrovascular disease was assessed by an independent physician. RESULTS: Forty-nine patients had no detectable retinal changes (grade 1), 13 had grade 2 retinopathy, and 18 had more advanced retinopathy (grades 3-6). Compared to patients without retinopathy (grade 1), patients with grades 2......BACKGROUND: In nondiabetic subjects pulse pressure (PP) is an independent predictor of cardiovascular disease and microalbuminuria. Reduced circadian blood pressure (BP) variation is a potential risk factor for the development of diabetic complications. We investigated the association between...

Amplitude-modulated fiber-ring laser

DEFF Research Database (Denmark)

Caputo, J. G.; Clausen, Carl A. Balslev; Sørensen, Mads Peter

2000-01-01

Soliton pulses generated by a fiber-ring laser are investigated by numerical simulation and perturbation methods. The mathematical modeling is based on the nonlinear Schrödinger equation with perturbative terms. We show that active mode locking with an amplitude modulator leads to a self......-starting of stable solitonic pulses from small random noise, provided the modulation depth is small. The perturbative analysis leads to a nonlinear coupled return map for the amplitude, phase, and position of the soliton pulses circulating in the fiber-ring laser. We established the validity of this approach...

Mechanism for the generation of cavitation maxima by pulsed ultrasound

International Nuclear Information System (INIS)

Flynn, H.G.; Church, C.C.

1984-01-01

A train of 1-MHz pulses can generate maxima of cavitation activity at pulse lengths of 6 and 60 ms and at pressure amplitudes, P/sub A/, between 5.4 and 9.4 bars (or intensities between 10 and 30 W/cm 2 ). Generation of maxima at P/sub A/ between these limits on pressure amplitude implies that the increase in cavitation activity originates from gas nuclei with radii lying in a critical size range centered at about 0.08 μm. The mechanism proposed for this phenomenon suggests that nuclei in this critical range are unstabilized nuclei generated in one pulse and surviving to the next with an appreciable fraction of the survivors lying in the critical range. Transient cavities that grow from such small nuclei are shown to behave as isolated mechanical systems that on reaching maximum size collapse as imploding spheres. The maximum pressures reached in such imploding cavities would then approximate those calculated for the spherical collapse of cavities. The occurrence of the observed maxima is ascribed to the spherical collapse of transient cavities. 17 references, 5 figures

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

NARCIS (Netherlands)

L.V. Wain (Louise); G.C. Verwoert (Germaine); P.F. O'Reilly (Paul); G. Shi (Gang); T. Johnson (Toby); M. Bochud (Murielle); K. Rice (Kenneth); P. Henneman (Peter); A.V. Smith (Albert Vernon); G.B. Ehret (Georg); N. Amin (Najaf); M.G. Larson (Martin); V. Mooser (Vincent); D. Hadley (David); M. Dörr (Marcus); J.C. Bis (Joshua); T. Aspelund (Thor); T. Esko (Tõnu); A.C.J.W. Janssens (Cécile); J.H. Zhao (Jing Hua); S.C. Heath (Simon); M. Laan (Maris); J. Fu (Jingyuan); G. Pistis (Giorgio); J. Luan; G. Lucas (Gavin); N. Pirastu (Nicola); I. Pichler (Irene); A.U. Jackson (Anne); R.J. Webster (Rebecca J.); F.F. Zhang; J. Peden (John); R. Schmidt (Reinhold); T. Tanaka (Toshiko); H. Campbell (Harry); W. Igl (Wilmar); Y. Milaneschi (Yuri); J.J. Hottenga (Jouke Jan); V. Vitart (Veronique); D.I. Chasman (Daniel); S. Trompet (Stella); J.L. Bragg-Gresham (Jennifer L.); B.Z. Alizadeh (Behrooz); J.C. Chambers (John); X. Guo (Xiuqing); T. Lehtimäki (Terho); B. Kuhnel (Brigitte); L.M. Lopez; O. Polasek (Ozren); M. Boban (Mladen); C.P. Nelson (Christopher P.); A.C. Morrison (Alanna); V. Pihur (Vasyl); S.K. Ganesh (Santhi); A. Hofman (Albert); S. Kundu (Suman); F.U.S. Mattace Raso (Francesco); F. Rivadeneira Ramirez (Fernando); E.J.G. Sijbrands (Eric); A.G. Uitterlinden (André); S.J. Hwang; R.S. Vasan (Ramachandran Srini); Y.A. Wang (Ying); S.M. Bergmann (Sven); P. Vollenweider (Peter); G. Waeber (Gérard); J. Laitinen (Jaana); A. Pouta (Anneli); P. Zitting (Paavo); W.L. McArdle (Wendy); H.K. Kroemer (Heyo); U. Völker (Uwe); H. Völzke (Henry); N.L. Glazer (Nicole); K.D. Taylor (Kent); T.B. Harris (Tamara); H. Alavere (Helene); T. Haller (Toomas); A. Keis (Aime); M.L. Tammesoo; Y.S. Aulchenko (Yurii); K-T. Khaw (Kay-Tee); P. Galan (Pilar); S. Hercberg (Serge); G.M. Lathrop (Mark); S. Eyheramendy (Susana); E. Org (Elin); S. Sõber (Siim); X. Lu (Xiaowen); I.M. Nolte (Ilja); B.W.J.H. Penninx (Brenda); T. Corre (Tanguy); C. Masciullo (Corrado); C. Sala (Cinzia); L. Groop (Leif); B.F. Voight (Benjamin); O. Melander (Olle); C.J. O'Donnell (Christopher); V. Salomaa (Veikko); P. d' Adamo (Pio); A. Fabretto (Antonella); F. Faletra (Flavio); S. Ulivi (Shelia); F. Del Greco M (Fabiola); M.F. Facheris (Maurizio); F.S. Collins (Francis); R.N. Bergman (Richard); J.P. Beilby (John); J. Hung (Judy); A.W. Musk (Arthur); M. Mangino (Massimo); S.Y. Shin (So Youn); N. Soranzo (Nicole); H. Watkins (Hugh); A. Goel (Anuj); A. Hamsten (Anders); P. Gider (Pierre); M. Loitfelder (Marisa); M. Zeginigg (Marion); D.G. Hernandez (Dena); S.S. Najjar (Samer); P. Navarro (Pau); S.H. Wild (Sarah); A.M. Corsi (Anna Maria); A. Singleton (Andrew); E.J.C. de Geus (Eco); G.A.H.M. Willemsen (Gonneke); A.N. Parker (Alex); L.M. Rose (Lynda); B.M. Buckley (Brendan M.); D.J. Stott (David. J.); M. Orrù (Marco); M. Uda (Manuela); M.M. van der Klauw (Melanie); X. Li (Xiaohui); J. Scott (James); Y.D.I. Chen (Yii-Der Ida); G.L. Burke (Greg); M. Kähönen (Mika); J. Viikari (Jorma); A. Döring (Angela); T. Meitinger (Thomas); G.S. Davis; J.M. Starr (John); V. Emilsson (Valur); A.S. Plump (Andrew); J.H. Lindeman (Jan H.); P.A.C. 't Hoen (Peter); I.R. König (Inke); J.F. Felix (Janine); R. Clarke; J. Hopewell; H. Ongen (Halit); M.M.B. Breteler (Monique); S. Debette (Stéphanie); A.L. DeStefano (Anita); M. Fornage (Myriam); G.F. Mitchell (Gary); H. Holm (Hilma); K. Stefansson (Kari); G. Thorleifsson (Gudmar); U. Thorsteinsdottir (Unnur); N.J. Samani (Nilesh); M. Preuss (Michael); I. Rudan (Igor); C. Hayward (Caroline); I.J. Deary (Ian); H.E. Wichmann (Heinz Erich); O. Raitakari (Olli); W. Palmas (Walter); J.S. Kooner (Jaspal); R.P. Stolk (Ronald); J.W. Jukema (Jan Wouter); A.F. Wright (Alan); D.I. Boomsma (Dorret); S. Bandinelli (Stefania); U. Gyllensten (Ulf); J.F. Wilson (James); L. Ferrucci (Luigi); M. Farrall (Martin); T.D. Spector (Timothy); L.J. Palmer; J. Tuomilehto (Jaakko); A. Pfeufer (Arne); P. Gasparini (Paolo); D.S. Siscovick (David); D. Altshuler (David); R.J.F. Loos (Ruth); D. Toniolo (Daniela); H. Snieder (Harold); C. Gieger (Christian); P. Meneton (Pierre); N.J. Wareham (Nick); B.A. Oostra (Ben); A. Metspalu (Andres); L.J. Launer (Lenore); R. Rettig (Rainer); D.P. Strachan (David); J.S. Beckmann (Jacques); J.C.M. Witteman (Jacqueline); J.A.P. Willems van Dijk (Ko); E.A. Boerwinkle (Eric); M. Boehnke (Michael); P.M. Ridker (Paul); M.R. Järvelin; A. Chakravarti (Aravinda); J. Erdmann (Jeanette); V. Gudnason (Vilmundur); C. Newton-Cheh (Christopher); D. Levy (Daniel); P. Arora (Pankaj); P. Munroe (Patricia); B.M. Psaty (Bruce); M. Caulfield (Mark); D.C. Rao (Dabeeru C.); P. Elliott (Paul); P. Tikka-Kleemola (Päivi); G.R. Abecasis (Gonçalo); I.E. Barroso (Inês)

2011-01-01

textabstractNumerous genetic loci have been associated with systolic blood pressure (SBP) and diastolic blood pressure (DBP) in Europeans. We now report genome-wide association studies of pulse pressure (PP) and mean arterial pressure (MAP). In discovery (N = 74,064) and follow-up studies (N =

Test-retest reliability of pulse amplitude tonometry measures of vascular endothelial function: implications for clinical trial design.

Science.gov (United States)

McCrea, Cindy E; Skulas-Ray, Ann C; Chow, Mosuk; West, Sheila G

2012-02-01

Endothelial dysfunction is an important outcome for assessing vascular health in intervention studies. However, reliability of the standard non-invasive method (flow-mediated dilation) is a significant challenge for clinical applications and multicenter trials. We evaluated the repeatability of pulse amplitude tonometry (PAT) to measure change in pulse wave amplitude during reactive hyperemia (Itamar Medical Ltd, Caesarea, Israel). Twenty healthy adults completed two PAT tests (mean interval = 19.5 days) under standardized conditions. PAT-derived measures of endothelial function (reactive hyperemia index, RHI) and arterial stiffness (augmentation index, AI) showed strong repeatability (intra-class correlations = 0.74 and 0.83, respectively). To guide future research, we also analyzed sample size requirements for a range of effect sizes. A crossover design powered at 0.90 requires 28 participants to detect a 15% change in RHI. Our study is the first to show that PAT measurements are repeatable in adults over an interval greater than 1 week.

Pulsed operation of high-pressure-sodium discharge lamps

International Nuclear Information System (INIS)

Guenther, K.; Kloss, H.G.; Lehmann, T.; Radtke, R.; Serick, F.

1990-01-01

Results of spectral and photometric measurements are presented for pulsed operated high-pressure-sodium lamps. Choosing for the colour temperature a value of 3000 K, the output spectrum was optimized with respect to colour rendition and lamp efficacy taking the pulse parameters, the sodium mole fraction, and the cold spot temperature as quantities to be varied. For the nominal rating of 70 W a maximum lamp efficacy of 70 lm/W and a colour rendering index of 40 can be obtained. Further improvements of the colour rendition require an enhanced sodium vapour pressure which can be achieved by operating the lamp at rised cold spot temperature. (orig.)

Pulsed operation of high-pressure-sodium discharge lamps

Energy Technology Data Exchange (ETDEWEB)

Guenther, K; Kloss, H G; Lehmann, T [Zentrum fuer Forschung und Technologie, Berlin (Germany, F.R.); Radtke, R; Serick, F [Zentralinstitut fuer Elektronenphysik, Berlin (Germany, F.R.)

1990-01-01

Results of spectral and photometric measurements are presented for pulsed operated high-pressure-sodium lamps. Choosing for the colour temperature a value of 3000 K, the output spectrum was optimized with respect to colour rendition and lamp efficacy taking the pulse parameters, the sodium mole fraction, and the cold spot temperature as quantities to be varied. For the nominal rating of 70 W a maximum lamp efficacy of 70 lm/W and a colour rendering index of 40 can be obtained. Further improvements of the colour rendition require an enhanced sodium vapour pressure which can be achieved by operating the lamp at rised cold spot temperature. (orig.).

A compact nanosecond pulse generator for DBD tube characterization

Science.gov (United States)

Rai, S. K.; Dhakar, A. K.; Pal, U. N.

2018-03-01

High voltage pulses of very short duration and fast rise time are required for generating uniform and diffuse plasma under various operating conditions. Dielectric Barrier Discharge (DBD) has been generated by high voltage pulses of short duration and fast rise time to produce diffuse plasma in the discharge gap. The high voltage pulse power generators have been chosen according to the requirement for the DBD applications. In this paper, a compact solid-state unipolar pulse generator has been constructed for characterization of DBD plasma. This pulsar is designed to provide repetitive pulses of 315 ns pulse width, pulse amplitude up to 5 kV, and frequency variation up to 10 kHz. The amplitude of the output pulse depends on the dc input voltage. The output frequency has been varied by changing the trigger pulse frequency. The pulsar is capable of generating pulses of positive or negative polarity by changing the polarity of pulse transformer's secondary. Uniform and stable homogeneous dielectric barrier discharge plasma has been produced successfully in a xenon DBD tube at 400-mbar pressure using the developed high voltage pulse generator.

Nanosecond pulsed power generator for a voltage amplitude up to 300 kV and a repetition rate up to 16 Hz for fine disintegration of quartz

Energy Technology Data Exchange (ETDEWEB)

Krastelev, E. G., E-mail: ekrastelev@yandex.ru; Sedin, A. A.; Tugushev, V. I. [Russian Academy of Sciences, Joint Institute for High Temperatures (Russian Federation)

2015-12-15

A generator of high-power high-voltage nanosecond pulses is intended for electrical discharge disintegration of mineral quartz and other nonconducting minerals. It includes a 320 kV Marx pulsed voltage generator, a high-voltage glycerin-insulated coaxial peaking capacitor, and an output gas spark switch followed by a load, an electric discharge disintegration chamber. The main parameters of the generator are as follows: a voltage pulse amplitude of up to 300 kV, an output impedance of ≈10 Ω, a discharge current amplitude of up to 25 kA for a half-period of 80–90 ns, and a pulse repetition rate of up to 16 Hz.

Nanosecond pulsed power generator for a voltage amplitude up to 300 kV and a repetition rate up to 16 Hz for fine disintegration of quartz

International Nuclear Information System (INIS)

Krastelev, E. G.; Sedin, A. A.; Tugushev, V. I.

2015-01-01

A generator of high-power high-voltage nanosecond pulses is intended for electrical discharge disintegration of mineral quartz and other nonconducting minerals. It includes a 320 kV Marx pulsed voltage generator, a high-voltage glycerin-insulated coaxial peaking capacitor, and an output gas spark switch followed by a load, an electric discharge disintegration chamber. The main parameters of the generator are as follows: a voltage pulse amplitude of up to 300 kV, an output impedance of ≈10 Ω, a discharge current amplitude of up to 25 kA for a half-period of 80–90 ns, and a pulse repetition rate of up to 16 Hz

Experimental study and modelisation of a pulse tube refrigerator

International Nuclear Information System (INIS)

Ravex, A.; Rolland, P.; Liang, J.

1992-01-01

A test bench for pulse tube refrigerator characterization has been built. In various configurations (basic pulse tube, orifice pulse tube and double inlet pulse tube), the ultimate temperature and the cooling power have been measured as a function of pressure wave amplitude and frequency for various geometries. A lowest temperature of 28 K has been achieved in a single staged double inlet configuration. A modelisation taking into account wall heat pumping, enthalpy flow and regenerator inefficiency is under development. Preliminary calculation results are compared with experimental data

The impact of sedation on pulse pressure variation

Czech Academy of Sciences Publication Activity Database

Zvoníček, V.; Jurák, Pavel; Halámek, Josef; Kružliak, P.; Vondra, Vlastimil; Leinveber, P.; Cundrle, I.; Pavlík, M.; Suk, P.; Šrámek, V.

2015-01-01

Roč. 28, č. 4 (2015), s. 203-207 ISSN 1036-7314 R&D Projects: GA MŠk(CZ) LO1212 Institutional support: RVO:68081731 Keywords : pulse pressure variation * sedation * heart lung interactions * mechanical ventilation * brain death * oesophageal pressure Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery Impact factor: 1.479, year: 2015

A method to reduce the suppression of relevant pulses in pulse weight discriminators

International Nuclear Information System (INIS)

Schwartz, P.

1975-01-01

The pulse height analyzer is used, for instance, with proportional counters. Pulses are broken down into amplitude ranges in accordance with their maximum amplitudes. In pulse height analyzers with real time analog-digital conversion only one deadtime is needed for the respective range selected. For this purpose, all discriminator thresholds of the amplitude stores connected parallel are actuated as an input pulse arrives. The leading edges of the discriminator signals set the amplitude range flip-flop. Only the flip-flop circuit of the maximum amplitude range reached remains set whilst all the others are erased. The trailing edge of the discriminator signals actuates the evaluation of the information stored by the flip-flop circuit selected. It triggers a pulse extender and resets the flip-flop selected. Therefore, only the amplitude range selected needs a deadtime. The pulse extender in addition reduces the processing time of the analyzer by the output pulse length. The characteristic used for the trailing edge is the backward count of the real time analog-digital converter. (DG/RF) [de

Fluctuation of blood pressure and pulse rate during colostomy irrigation.

Science.gov (United States)

Sadahiro, S; Noto, T; Tajima, T; Mitomi, T; Miyazaki, T; Numata, M

1995-06-01

The aim of this study was to determine the effects of colostomy irrigation on the vital signs of patients with left colostomy. Twenty-two consecutive patients who underwent abdominoperineal resection for cancer of the lower rectum and had left lower quadrant end colostomy were included in this study. Subjective symptoms, blood pressure, and pulse rate during the first irrigation were investigated. Fluctuation of blood pressure during instillation was 8.0/8.5 mmHg (average) and 25.0/17.9 mmHg during evacuation. Fluctuation of pulse rate was 5.5 per minute (average) during instillation and 11.5 per minute during evacuation. The number of subjects who showed more than 20% fluctuation of systolic pressure was 12 (54.5 percent) and that of diastolic pressure was 14 (63.6 percent). One of 22 patients complained of illness during irrigation. Although colostomy irrigation showed no significant effects on vital signs in the majority of patients, it caused a significant reduction in both blood pressure and pulse rate in a small number of patients. Careful attention should be paid to vital signs considering the possibility of such effects, especially on the initial irrigation.

Ozone formation in pulsed SDBD in a wide pressure range

Science.gov (United States)

Starikovskiy, Andrey; Nudnova, Maryia; mipt Team

2011-10-01

Ozone concentration in surface anode-directed DBD for wide pressure range (150 - 1300 torr) was experimentally measured. Voltage and pressure effect were investigated. Reduced electric field was measured for anode-directed and cathode-directed SDBD. E/n values in cathode-directed SDBD is higher than in cathode-directed on 50 percent at atmospheric pressure. E/n value increase leads to decrease the rate of oxygen dissociation and Ozone formation at lower pressures. Radiating region thickness of sliding discharge was measured. Typical thickness of radiating zone is 0.4-1.0 mm within pressure range 220-740 torr. It was shown that high-voltage pulsed nanosecond discharge due to high E/n value produces less Ozone with compare to other discharges. Kinetic model was proposed to describe Ozone formation in the pulsed nanosecond SDBD.

Improving quality of laser scanning data acquisition through calibrated amplitude and pulse deviation measurement

Science.gov (United States)

Pfennigbauer, Martin; Ullrich, Andreas

2010-04-01

Newest developments in laser scanner technologies put surveyors in the position to comply with the ever increasing demand of high-speed, high-accuracy, and highly reliable data acquisition from terrestrial, mobile, and airborne platforms. Echo digitization in pulsed time-of-flight laser ranging has demonstrated its superior performance in the field of bathymetry and airborne laser scanning for more than a decade, however at the cost of somewhat time consuming off line post processing. State-of-the-art online waveform processing as implemented in RIEGL's V-Line not only saves users post-processing time to obtain true 3D point clouds, it also adds the assets of calibrated amplitude and reflectance measurement for data classification and pulse deviation determination for effective and reliable data validation. We present results from data acquisitions in different complex target situations.

Relationship between Resting Heart Rate, Blood Pressure and Pulse Pressure in Adolescents.

Science.gov (United States)

Christofaro, Diego Giulliano Destro; Casonatto, Juliano; Vanderlei, Luiz Carlos Marques; Cucato, Gabriel Grizzo; Dias, Raphael Mendes Ritti

2017-05-01

High resting heart rate is considered an important factor for increasing mortality chance in adults. However, it remains unclear whether the observed associations would remain after adjustment for confounders in adolescents. To analyze the relationship between resting heart rate, blood pressure and pulse pressure in adolescents of both sexes. A cross-sectional study with 1231 adolescents (716 girls and 515 boys) aged 14-17 years. Heart rate, blood pressure and pulse pressure were evaluated using an oscillometric blood pressure device, validated for this population. Weight and height were measured with an electronic scale and a stadiometer, respectively, and waist circumference with a non-elastic tape. Multivariate analysis using linear regression investigated the relationship between resting heart rate and blood pressure and pulse pressure in boys and girls, controlling for general and abdominal obesity. Higher resting heart rate values were observed in girls (80.1 ± 11.0 beats/min) compared to boys (75.9 ± 12.7 beats/min) (p ≤ 0.001). Resting heart rate was associated with systolic blood pressure in boys (Beta = 0.15 [0.04; 0.26]) and girls (Beta = 0.24 [0.16; 0.33]), with diastolic blood pressure in boys (Beta = 0.50 [0.37; 0.64]) and girls (Beta = 0.41 [0.30; 0.53]), and with pulse pressure in boys (Beta = -0.16 [-0.27; -0.04]). This study demonstrated a relationship between elevated resting heart rate and increased systolic and diastolic blood pressure in both sexes and pulse pressure in boys even after controlling for potential confounders, such as general and abdominal obesity. A frequência cardíaca de repouso é considerada um importante fator de aumento de mortalidade em adultos. Entretanto, ainda é incerto se as associações observadas permanecem após ajuste para fatores de confusão em adolescentes. Analisar a relação entre frequência cardíaca de repouso, pressão arterial e pressão de pulso em adolescentes dos dois sexos. Estudo transversal

Vascular Stiffness and Increased Pulse Pressure in the Aging Cardiovascular System

Directory of Open Access Journals (Sweden)

Jochen Steppan

2011-01-01

Full Text Available Aging leads to a multitude of changes in the cardiovascular system, including systolic hypertension, increased central vascular stiffness, and increased pulse pressure. In this paper we will review the effects of age-associated increased vascular stiffness on systolic blood pressure, pulse pressure, augmentation index, and cardiac workload. Additionally we will describe pulse wave velocity as a method to measure vascular stiffness and review the impact of increased vascular stiffness as an index of vascular health and as a predictor of adverse cardiovascular outcomes. Furthermore, we will discuss the underlying mechanisms and how these may be modified in order to change the outcomes. A thorough understanding of these concepts is of paramount importance and has therapeutic implications for the increasingly elderly population.

Particle image velocimetry investigation of a finite amplitude pressure wave

Science.gov (United States)

Thornhill, D.; Currie, T.; Fleck, R.; Chatfield, G.

2006-03-01

Particle image velocimetry is used to study the motion of gas within a duct subject to the passage of a finite amplitude pressure wave. The wave is representative of the pressure waves found in the exhaust systems of internal combustion engines. Gas particles are accelerated from stationary to 150 m/s and then back to stationary in 8 ms. It is demonstrated that gas particles at the head of the wave travel at the same velocity across the duct cross section at a given point in time. Towards the tail of the wave viscous effects are plainly evident causing the flow profile to tend towards parabolic. However, the instantaneous mean particle velocity across the section is shown to match well with the velocity calculated from a corresponding measured pressure history using 1D gas dynamic theory. The measured pressure history at a point in the duct was acquired using a high speed pressure transducer of the type typically used for engine research in intake and exhaust systems. It is demonstrated that these are unable to follow the rapid changes in pressure accurately and that they are prone to resonate under certain circumstances.

Smartphone-based Continuous Blood Pressure Measurement Using Pulse Transit Time.

Science.gov (United States)

Gholamhosseini, Hamid; Meintjes, Andries; Baig, Mirza; Linden, Maria

2016-01-01

The increasing availability of low cost and easy to use personalized medical monitoring devices has opened the door for new and innovative methods of health monitoring to emerge. Cuff-less and continuous methods of measuring blood pressure are particularly attractive as blood pressure is one of the most important measurements of long term cardiovascular health. Current methods of noninvasive blood pressure measurement are based on inflation and deflation of a cuff with some effects on arteries where blood pressure is being measured. This inflation can also cause patient discomfort and alter the measurement results. In this work, a mobile application was developed to collate the PhotoPlethysmoGramm (PPG) waveform provided by a pulse oximeter and the electrocardiogram (ECG) for calculating the pulse transit time. This information is then indirectly related to the user's systolic blood pressure. The developed application successfully connects to the PPG and ECG monitoring devices using Bluetooth wireless connection and stores the data onto an online server. The pulse transit time is estimated in real time and the user's systolic blood pressure can be estimated after the system has been calibrated. The synchronization between the two devices was found to pose a challenge to this method of continuous blood pressure monitoring. However, the implemented continuous blood pressure monitoring system effectively serves as a proof of concept. This combined with the massive benefits that an accurate and robust continuous blood pressure monitoring system would provide indicates that it is certainly worthwhile to further develop this system.

Single pulse analysis of intracranial pressure for a hydrocephalus implant.

Science.gov (United States)

Elixmann, I M; Hansinger, J; Goffin, C; Antes, S; Radermacher, K; Leonhardt, S

2012-01-01

The intracranial pressure (ICP) waveform contains important diagnostic information. Changes in ICP are associated with changes of the pulse waveform. This change has explicitly been observed in 13 infusion tests by analyzing 100 Hz ICP data. An algorithm is proposed which automatically extracts the pulse waves and categorizes them into predefined patterns. A developed algorithm determined 88 %±8 % (mean ±SD) of all classified pulse waves correctly on predefined patterns. This algorithm has low computational cost and is independent of a pressure drift in the sensor by using only the relationship between special waveform characteristics. Hence, it could be implemented on a microcontroller of a future electromechanic hydrocephalus shunt system to control the drainage of cerebrospinal fluid (CSF).

Arterial blood pressure measurement and pulse wave analysis—their role in enhancing cardiovascular assessment

International Nuclear Information System (INIS)

Avolio, Alberto P; Butlin, Mark; Walsh, Andrew

2010-01-01

The most common method of clinical measurement of arterial blood pressure is by means of the cuff sphygmomanometer. This instrument has provided fundamental quantitative information on arterial pressure in individual subjects and in populations and facilitated estimation of cardiovascular risk related to levels of blood pressure obtained from the brachial cuff. Although the measurement is taken in a peripheral limb, the values are generally assumed to reflect the pressure throughout the arterial tree in large conduit arteries. Since the arterial pressure pulse becomes modified as it travels away from the heart towards the periphery, this is generally true for mean and diastolic pressure, but not for systolic pressure, and so pulse pressure. The relationship between central and peripheral pulse pressure depends on propagation characteristics of arteries. Hence, while the sphygmomanometer gives values of two single points on the pressure wave (systolic and diastolic pressure), there is additional information that can be obtained from the time-varying pulse waveform that enables an improved quantification of the systolic load on the heart and other central organs. This topical review will assess techniques of pressure measurement that relate to the use of the cuff sphygmomanometer and to the non-invasive registration and analysis of the peripheral and central arterial pressure waveform. Improved assessment of cardiovascular function in relation to treatment and management of high blood pressure will result from future developments in the indirect measurement of arterial blood pressure that involve the conventional cuff sphygmomanometer with the addition of information derived from the peripheral arterial pulse. (topical review)

Simulations of piezoelectric pressure sensor for radial artery pulse measurement

Energy Technology Data Exchange (ETDEWEB)

Joshi, Abhay B. [Department of Electronic Science, University of Pune, Pune 411 007 (India); Kalange, Ashok E. [Department of Electronic Science, University of Pune, Pune 411 007 (India); Tuljaram Chaturchand College, Baramati 413 102 (India); Bodas, Dhananjay, E-mail: dhananjay.bodas@gmail.co [Center for Nanobio Sciences, Agharkar Research Institute, Pune 411 004 (India); Gangal, S.A. [Department of Electronic Science, University of Pune, Pune 411 007 (India)

2010-04-15

A radial artery pulse is used to diagnose human body constitution (Prakruti) in Ayurveda. A system consisting of piezoelectric sensor (22 mm x 12 mm), data acquisition card and LabView software was used to record the pulse data. The pulse obtained from the sensor was noisy, even though signal processing was done. Moreover due to large sized senor accurate measurements were not possible. Hence, a need was felt to develop a sensor of the size of the order of finger tip with a resonant frequency of the order of 1 Hz. A micromachined pressure sensor based on piezoelectric sensing mechanism was designed and simulated using CoventorWare. Simulations were carried out by varying dimensions of the sensor to optimize the resonant frequency, stresses and voltage generated as a function of applied pressure. All simulations were done with pressure ranging of 1-30 kPa, which is the range used by Ayurvedic practitioners for diagnosis. Preliminary work on fabrication of such a sensor was carried out successfully.

Simulations of piezoelectric pressure sensor for radial artery pulse measurement

International Nuclear Information System (INIS)

Joshi, Abhay B.; Kalange, Ashok E.; Bodas, Dhananjay; Gangal, S.A.

2010-01-01

A radial artery pulse is used to diagnose human body constitution (Prakruti) in Ayurveda. A system consisting of piezoelectric sensor (22 mm x 12 mm), data acquisition card and LabView software was used to record the pulse data. The pulse obtained from the sensor was noisy, even though signal processing was done. Moreover due to large sized senor accurate measurements were not possible. Hence, a need was felt to develop a sensor of the size of the order of finger tip with a resonant frequency of the order of 1 Hz. A micromachined pressure sensor based on piezoelectric sensing mechanism was designed and simulated using CoventorWare. Simulations were carried out by varying dimensions of the sensor to optimize the resonant frequency, stresses and voltage generated as a function of applied pressure. All simulations were done with pressure ranging of 1-30 kPa, which is the range used by Ayurvedic practitioners for diagnosis. Preliminary work on fabrication of such a sensor was carried out successfully.

Prediction of electromagnetic pulse generation by picosecond avalanches in high-pressure air

International Nuclear Information System (INIS)

Mayhall, D.J.; Yee, J.H.

1993-01-01

The gas avalanche switch is a laser-activated, high-voltage switch, consisting of a set of pulse-charged electrodes in a high-pressure gas. Induced electrons from a picosecond-scale laser pulse initiate an avalanche discharge between high-voltage and grounded electrodes. If the voltage, pressure, and dimensions are correct, the rapid avalanche, fueled by the immense number of electrons available in the gas, collapses the applied voltage in picoseconds and generates electromagnetic pulses with widths as short as 1-10 ps and 3 dB bandwidths of 20-120 GHz. With proper voltage or pressure detuning, wider pulses and lower bandwidths occur. In addition to picosecond electromagnetic pulse generation, application of this switch should result in ultra-fast Marx bank pulsers. A number of versions of the switch are possible. The simplest is a parallel plate capacitor, consisting of a gas between two parallel plate conductors. High voltage is applied across the two plates. A parallel plate, Blumlein geometry features a center electrode between two grounded parallel plates. This geometry emits a single pulse in each direction along the parallel plates. A frozen wave geometry with multiple, oppositely charged center electrodes will emit AC pulses. Series switches consisting of gas gaps between two electrodes are also possible

Long-duration nano-second single pulse lasers for observation of spectra from bulk liquids at high hydrostatic pressures

International Nuclear Information System (INIS)

Thornton, Blair; Sakka, Tetsuo; Masamura, Tatsuya; Tamura, Ayaka; Takahashi, Tomoko; Matsumoto, Ayumu

2014-01-01

The influence of laser pulse duration on the spectral emissions observed from bulk ionic solutions has been investigated for hydrostatic pressures between 0.1 and 30 MPa. Transient pressure, shadowgraph imaging and spectroscopic measurements were performed for single pulses of duration 20 and 150 ns. The transient pressure measurements show that for hydrostatic pressures up to 30 MPa, propagation of the high-pressure shockwave generated by the focused laser causes the local pressure to reduce below ambient levels during the time frame that spectroscopic measurements can be made. The pressure impulse and subsequent reduction in pressure are larger, with the latter lasting longer for the 150 ns pulse compared to a 20 ns pulse of the same energy. The 150 ns pulse generates larger cavities with significant enhancement of the spectral emissions observed compared to the 20 ns duration pulse for pressures up to 30 MPa. The results demonstrate that laser-induced breakdown using a long ns duration pulse offers an advantage over conventional, short ns duration pulses for the analysis of bulk ionic solutions at hydrostatic pressures between 0.1 and 30 MPa. - Highlights: • Long-ns-duration laser pulses enhance the spectra observed from bulk solutions. • Laser-induced shockwaves momentarily reduce pressures to below ambient levels. • 150 ns pulses generate larger cavities than 20 ns pulses of the same energy. • Hydrostatic pressures < 30 MPa have no significant effect on the observed spectra

Tracking a Solar Wind Dynamic Pressure Pulses' Impact Through the Magnetosphere Using the Heliophysics System Observatory

Science.gov (United States)

Vidal-Luengo, S.; Moldwin, M.

2017-12-01

During northward Interplanetary Magnetic Field (IMF) Bz conditions, the magnetosphere acts as a closed "cavity" and reacts to solar wind dynamic pressure pulses more simply than during southward IMF conditions. Effects of solar wind dynamic pressure have been observed as geomagnetic lobe compressions depending on the characteristics of the pressure pulse and the spacecraft location. One of the most important aspects of this study is the incorporation of simultaneous observations by different missions, such as WIND, CLUSTER, THEMIS, MMS, Van Allen Probes and GOES as well as magnetometer ground stations that allow us to map the magnetosphere response at different locations during the propagation of a pressure pulse. In this study we used the SYM-H as an indicator of dynamic pressure pulses occurrence from 2007 to 2016. The selection criteria for events are: (1) the increase in the index must be bigger than 10 [nT] and (2) the rise time must be in less than 5 minutes. Additionally, the events must occur under northward IMF and at the same time at least one spacecraft has to be located in the magnetosphere nightside. Using this methodology we found 66 pressure pulse events for analysis. Most of them can be classified as step function pressure pulses or as sudden impulses (increase followed immediately by a decrease of the dynamic pressure). Under these two categories the results show some systematic signatures depending of the location of the spacecraft. For both kind of pressure pulse signatures, compressions are observed on the dayside. However, on the nightside compressions and/or South-then-North magnetic signatures can be observed for step function like pressure pulses, meanwhile for the sudden impulse kind of pressure pulses the magnetospheric response seems to be less global and more dependent on the local conditions.

Effect of Fuel Injection and Mixing Characteristics on Pulse-Combustor Performance at High-Pressure

Science.gov (United States)

Yungster, Shaye; Paxson, Daniel E.; Perkins, Hugh D.

2014-01-01

Recent calculations of pulse-combustors operating at high-pressure conditions produced pressure gains significantly lower than those observed experimentally and computationally at atmospheric conditions. The factors limiting the pressure-gain at high-pressure conditions are identified, and the effects of fuel injection and air mixing characteristics on performance are investigated. New pulse-combustor configurations were developed, and the results show that by suitable changes to the combustor geometry, fuel injection scheme and valve dynamics the performance of the pulse-combustor operating at high-pressure conditions can be increased to levels comparable to those observed at atmospheric conditions. In addition, the new configurations can significantly reduce the levels of NOx emissions. One particular configuration resulted in extremely low levels of NO, producing an emission index much less than one, although at a lower pressure-gain. Calculations at representative cruise conditions demonstrated that pulse-combustors can achieve a high level of performance at such conditions.

Does aqueductal stenosis influence the lumbar infusion test in normal-pressure hydrocephalus?

Science.gov (United States)

González-Martínez, Emilio Luis; Santamarta, David

2016-12-01

Late-onset idiopathic aqueductal stenosis may present with clinical features indistinct from idiopathic normal-pressure hydrocephalus (NPH). Moreover, aqueductal stenosis (AS) is not always detected by conventional magnetic resonance imaging (MRI). The aim of this study was to compare the hydrodynamic pattern among NPH patients according to the patency of the aqueduct. Fifty-six consecutive lumbar infusion tests were performed in patients with NPH syndrome. Precipitating causes of hydrocephalus were excluded, and aqueductal patency was examined through high-resolution, T2-weighted 3D MRI. Patients were classified into two groups: non-patent aqueduct and patent aqueduct. Mean values of pressure and pulse amplitude were obtained from basal and plateau stages of infusion studies. Twelve of 56 patients with NPH-like symptoms presented with morphological AS (21.4 %). Patent aqueduct and non-patent aqueduct groups had similar values of mean opening lumbar pressure (8.2 vs. 8.1 mmHg), and mean opening pulse amplitude (3.1 vs. 2.9 mmHg). Mean pressure in the plateau stage (28.6 vs. 23.2 mmHg), and mean pulse amplitude in the plateau stage (12.5 vs. 10.6 mmHg) were higher in the patent aqueduct group. These differences were not statistically significant. Only Rout was significantly higher in the patent aqueduct group (13.6 vs. 10.1 mmHg/ml/min). One-third of NPH patients with AS presented Rout >12 mmHg/ml/min. No differences in mean pressure or pulse amplitude during basal and plateau epochs of the lumbar infusion test in NPH patients were detected, regardless of aqueductal patency. However, Rout was significantly higher in patients with patent aqueduct.

Differential pulse amplitude modulation for multiple-input single-output OWVLC

Science.gov (United States)

Yang, S. H.; Kwon, D. H.; Kim, S. J.; Son, Y. H.; Han, S. K.

2015-01-01

White light-emitting diodes (LEDs) are widely used for lighting due to their energy efficiency, eco-friendly, and small size than previously light sources such as incandescent, fluorescent bulbs and so on. Optical wireless visible light communication (OWVLC) based on LED merges lighting and communications in applications such as indoor lighting, traffic signals, vehicles, and underwater communications because LED can be easily modulated. However, physical bandwidth of LED is limited about several MHz by slow time constant of the phosphor and characteristics of device. Therefore, using the simplest modulation format which is non-return-zero on-off-keying (NRZ-OOK), the data rate reaches only to dozens Mbit/s. Thus, to improve the transmission capacity, optical filtering and pre-, post-equalizer are adapted. Also, high-speed wireless connectivity is implemented using spectrally efficient modulation methods: orthogonal frequency division multiplexing (OFDM) or discrete multi-tone (DMT). However, these modulation methods need additional digital signal processing such as FFT and IFFT, thus complexity of transmitter and receiver is increasing. To reduce the complexity of transmitter and receiver, we proposed a novel modulation scheme which is named differential pulse amplitude modulation. The proposed modulation scheme transmits different NRZ-OOK signals with same amplitude and unit time delay using each LED chip, respectively. The `N' parallel signals from LEDs are overlapped and directly detected at optical receiver. Received signal is demodulated by power difference between unit time slots. The proposed scheme can overcome the bandwidth limitation of LEDs and data rate can be improved according to number of LEDs without complex digital signal processing.

Repetitively pulsed UV radiation source based on a run-away electron preionised diffuse discharge in nitrogen

Science.gov (United States)

Baksht, E. Kh; Burachenko, A. G.; Lomaev, M. I.; Panchenko, A. N.; Tarasenko, V. F.

2015-04-01

An extended repetitively pulsed source of spontaneous UV radiation is fabricated, which may also be used for producing laser radiation. Voltage pulses with an incident wave amplitude of up to 30 kV, a half-amplitude duration of ~4 ns and a rise time of ~2.5 ns are applied to a gap with a nonuniform electric field. For an excitation region length of 35 cm and a nitrogen pressure of 30 - 760 Torr, a diffusive discharge up to a pulse repetition rate of 2 kHz is produced without using an additional system for gap preionisation. An investigation is made of the plasma of the run-away electron preionised diffuse discharge. Using a CCD camera it is found that the dense diffused plasma fills the gap in a time shorter than 1 ns. X-ray radiation is recorded from behind the foil anode throughout the pressure range under study; a supershort avalanche electron beam is recorded by the collector electrode at pressures below 100 Torr.

Amplitude-to-frequency converter of radioisotope instruments

International Nuclear Information System (INIS)

Demchenkov, V.P.; Korobkov, I.N.

1988-01-01

An amplitude-to-frequency converter designed for signal processing of radioisotope relay devices is descibed. The basic elements of the converter are a scaling amplifier, an analog-to-digital converter, a code-to-frequency converter, a null-organ, a delay unit and a clock-pulse generator. The designed amplitude-to-frequency converter takes into account a prior information about the signal shape of the energy spectrum. The converter processes input pulses of 0.10 V amplitude and duration more than 2μs. The energy channel number is 64

Hydraulic pressure pulses with elastic and plastic structural flexibility: test and analysis (LWBR Development Program)

International Nuclear Information System (INIS)

Schwirian, R.E.

1978-03-01

Pressure pulse tests were conducted with a flexible test section in a test vessel filled with room temperature water. The pressure pulses were generated with a drop hammer and piston pulse generator and were of a sufficient magnitude to cause plastic deformation of the test section. Because of the strong pressure relief effect of the deforming test section, pressure pulse magnitudes were below 265 psig in magnitude and had durations of 50 to 55 msecs. Calculations performed with the FLASH-35 bi-linear hysteresis model of structural deformation show good agreement with experiment. In particular, FLASH 35 adequately predicts the decrease in peak pressure and the increase in pulse duration due to elastic and plastic deformation of the test section. Predictions of flexible member motion are good, but are less satisfactory than the pressure pulse results due to uncertainties in the values of yield point and beyond yield stiffness used to model the various flexible members. Coupled with this is a strong sensitivity of the FLASH 35 predictions to the values of yield point and beyond yield stiffness chosen for the various flexible members. The test data versus calculation comparisons presented here provide preliminary qualification for FLASH 35 calculations of transient hydraulic pressures and pressure differentials in the presence of flexible structural members which deform both elastically and plastically

Viscoelastic fingering with a pulsed pressure signal

International Nuclear Information System (INIS)

Corvera Poire, E; Rio, J A del

2004-01-01

We derive a generalized Darcy's law in the frequency domain for a linear viscoelastic fluid flowing in a Hele-Shaw cell. This leads to an analytic expression for the dynamic permeability that has maxima which are several orders of magnitude larger than the static permeability. We then follow an argument of de Gennes (1987 Europhys. Lett. 2 195) to obtain the smallest possible finger width when viscoelasticity is important. Using this and a conservation law, we obtain the lowest bound for the width of a single finger displacing a viscoelastic fluid. When the driving force consists of a constant pressure gradient plus an oscillatory signal, our results indicate that the finger width varies in time following the frequency of the incident signal. Also, the amplitude of the finger width in time depends on the value of the dynamic permeability at the imposed frequency. When the finger is driven with a frequency that maximizes the permeability, variations in the amplitude are also maximized. This gives results that are very different for Newtonian and viscoelastic fluids. For the former ones the amplitude of the oscillation decays with frequency. For the latter ones on the other hand, the amplitude has maxima at the same frequencies that maximize the dynamic permeability

Models of brachial to finger pulse wave distortion and pressure decrement

NARCIS (Netherlands)

Gizdulich, P.; Prentza, A.; Wesseling, K.H.

1997-01-01

Objective: To model the pulse wave distortion and pressure decrement occurring between brachial and finger arteries. Distortion reversion and decrement correction were also our aims. Methods: Brachial artery pressure was recorded intra-arterially and finger pressure was recorded non-invasively by

PLASMA SLOSHING IN PULSE-HEATED SOLAR AND STELLAR CORONAL LOOPS

Energy Technology Data Exchange (ETDEWEB)

Reale, F., E-mail: fabio.reale@unipa.it [Dipartimento di Fisica and Chimica, Università di Palermo, Piazza del Parlamento 1, I-90134 Palermo (Italy)

2016-08-01

There is evidence that coronal heating is highly intermittent, and flares are the high energy extreme. The properties of the heat pulses are difficult to constrain. Here, hydrodynamic loop modeling shows that several large amplitude oscillations (∼20% in density) are triggered in flare light curves if the duration of the heat pulse is shorter than the sound crossing time of the flaring loop. The reason for this is that the plasma does not have enough time to reach pressure equilibrium during heating, and traveling pressure fronts develop. The period is a few minutes for typical solar coronal loops, dictated by the sound crossing time in the decay phase. The long period and large amplitude make these oscillations different from typical magnetohydrodynamic (MHD) waves. This diagnostic can be applied both to observations of solar and stellar flares and to future observations of non-flaring loops at high resolution.

Generation of subnanosecond electron beams in air at atmospheric pressure

Science.gov (United States)

Kostyrya, I. D.; Tarasenko, V. F.; Baksht, E. Kh.; Burachenko, A. G.; Lomaev, M. I.; Rybka, D. V.

2009-11-01

Optimum conditions for the generation of runaway electron beams with maximum current amplitudes and densities in nanosecond pulsed discharges in air at atmospheric pressure are determined. A supershort avalanche electron beam (SAEB) with a current amplitude of ˜30 A, a current density of ˜20 A/cm2, and a pulse full width at half maximum (FWHM) of ˜100 ps has been observed behind the output foil of an air-filled diode. It is shown that the position of the SAEB current maximum relative to the voltage pulse front exhibits a time shift that varies when the small-size collector is moved over the foil surface.

Beat-to-Beat Blood Pressure Monitor

Science.gov (United States)

Lee, Yong Jin

2012-01-01

This device provides non-invasive beat-to-beat blood pressure measurements and can be worn over the upper arm for prolonged durations. Phase and waveform analyses are performed on filtered proximal and distal photoplethysmographic (PPG) waveforms obtained from the brachial artery. The phase analysis is used primarily for the computation of the mean arterial pressure, while the waveform analysis is used primarily to obtain the pulse pressure. Real-time compliance estimate is used to refine both the mean arterial and pulse pressures to provide the beat-to-beat blood pressure measurement. This wearable physiological monitor can be used to continuously observe the beat-to-beat blood pressure (B3P). It can be used to monitor the effect of prolonged exposures to reduced gravitational environments and the effectiveness of various countermeasures. A number of researchers have used pulse wave velocity (PWV) of blood in the arteries to infer the beat-to-beat blood pressure. There has been documentation of relative success, but a device that is able to provide the required accuracy and repeatability has not yet been developed. It has been demonstrated that an accurate and repeatable blood pressure measurement can be obtained by measuring the phase change (e.g., phase velocity), amplitude change, and distortion of the PPG waveforms along the brachial artery. The approach is based on comparing the full PPG waveform between two points along the artery rather than measuring the time-of-flight. Minimizing the measurement separation and confining the measurement area to a single, well-defined artery allows the waveform to retain the general shape between the two measurement points. This allows signal processing of waveforms to determine the phase and amplitude changes.

Amplitude-temporal characteristics of a supershort avalanche electron beam generated during subnanosecond breakdown in air and nitrogen

Science.gov (United States)

Tarasenko, V. F.; Baksht, E. Kh.; Beloplotov, D. V.; Burachenko, A. G.; Lomaev, M. I.

2016-04-01

The amplitude-temporal characteristics of a supershort avalanche electron beam (SAEB) with an amplitude of up to 100 A, as well as of the breakdown voltage and discharge current, are studied experimentally with a picosecond time resolution. The waveforms of discharge and SAEB currents are synchronized with those of the voltage pulses. It is shown that the amplitude-temporal characteristics of the SAEB depend on the gap length and the designs of the gas diode and cathode. The mechanism for the generation of runaway electron beams in atmospheric-pressure gases is analyzed on the basis of the obtained experimental data.

Amplitude-measuring devices for electric pulses in the nanosecond region; Dispositifs de mesure d'amplitude d'impulsions electriques dans le domaine de la nanoseconde; Pribory dlya izmereniya amplitudy ehlektricheskikh impul'sov v sfere nanosekundy; Dispositivos para medir la amplitud de los impulsos electricos en la region del nanosegundo

Energy Technology Data Exchange (ETDEWEB)

Samueli, J J; Sarazin, A [Institut d' Etudes Nucleaires d' Alger (France)

1962-04-15

Two electronic circuits are described which permit measurement of the maximum amplitude of fast pulses. These circuits are usually required, if possible, to give independent indication of the duration and shape of the signal being studied. The first circuit is a pulse expander, i.e. an apparatus for converting fast signals into pulses of constant width and of amplitude proportional to the amplitude sought, thus permitting the study of fast signals with a conventional amplitude selector. The circuit can accept signals of width greater than two nanoseconds and of amplitude between 1 and 15 V. It delivers two signals of constant width 100 ns and 1 {mu}s. The second circuit is a fast amplitude-discriminator with an adjustable threshold from 1 to 30 V and a reading space of approximately 18% for pulses of 100 and 2 ns. The output signal has an amplitude of 1.5 V and a standard width of 0.2 {mu}s. (author) [French] Les auteurs decrivent deux circuits electroniques permettant d'effectuer des mesures d'amplitude maximum d'impulsions rapides. On demande en general a ces circuits de donner une indication independante, si possible, de la duree et de la forme du signal etudie. Le premier circuit est un allongeur d'impulsions, c'est-a-dire un appareil qui convertit des signaux rapides en impulsions de largeur constante et d'amplitude proportionnelle a l'amplitude cherchee et qui permet donc l'etude des signaux rapides par un selecteur d'amplitude conventionnel. Le circuit accepte des signaux de largeur superieure a 2 ns et d'amplitude comprise entre 1 et 15 V. Il delivre deux signaux de largeur constante, 100 ns et 1 {mu}s. Le second circuit est un discriminateur d'amplitude rapide, de seuil ajustable de 1 a 30 V et dont l'ecart de lecture pour des impulsions de largeur de 100 et 2 ns est de l'ordre de 18%. Le signal de sortie a une amplitude de 1,5 V et une largeur standard de 0,2 {mu}s. (author) [Spanish] Los autores describen dos circuitos electronicos que permiten medir la

Tree shoot bending generates hydraulic pressure pulses: a new long-distance signal?

Science.gov (United States)

Lopez, Rosana; Badel, Eric; Peraudeau, Sebastien; Leblanc-Fournier, Nathalie; Beaujard, François; Julien, Jean-Louis; Cochard, Hervé; Moulia, Bruno

2014-05-01

When tree stems are mechanically stimulated, a rapid long-distance signal is induced that slows down primary growth. An investigation was carried out to determine whether the signal might be borne by a mechanically induced pressure pulse in the xylem. Coupling xylem flow meters and pressure sensors with a mechanical testing device, the hydraulic effects of mechanical deformation of tree stem and branches were measured. Organs of several tree species were studied, including gymnosperms and angiosperms with different wood densities and anatomies. Bending had a negligible effect on xylem conductivity, even when deformations were sustained or were larger than would be encountered in nature. It was found that bending caused transient variation in the hydraulic pressure within the xylem of branch segments. This local transient increase in pressure in the xylem was rapidly propagated along the vascular system in planta to the upper and lower regions of the stem. It was shown that this hydraulic pulse originates from the apoplast. Water that was mobilized in the hydraulic pulses came from the saturated porous material of the conduits and their walls, suggesting that the poroelastic behaviour of xylem might be a key factor. Although likely to be a generic mechanical response, quantitative differences in the hydraulic pulse were found in different species, possibly related to differences in xylem anatomy. Importantly the hydraulic pulse was proportional to the strained volume, similar to known thigmomorphogenetic responses. It is hypothesized that the hydraulic pulse may be the signal that rapidly transmits mechanobiological information to leaves, roots, and apices.

Effect of heat-induced pain stimuli on pulse transit time and pulse wave amplitude in healthy volunteers.

Science.gov (United States)

van Velzen, Marit H N; Loeve, Arjo J; Kortekaas, Minke C; Niehof, Sjoerd P; Mik, Egbert G; Stolker, Robert J

2016-01-01

Pain is commonly assessed subjectively by interpretations of patient behaviour and/or reports from patients. When this is impossible the availability of a quantitative objective pain assessment tool based on objective physiological parameters would greatly benefit clinical practice and research beside the standard self-report tests. Vasoconstriction is one of the physiological responses to pain. The aim of this study was to investigate whether pulse transit time (PTT) and pulse wave amplitude (PWA) decrease in response to this vasoconstriction when caused by heat-induced pain. The PTT and PWA were measured in healthy volunteers, on both index fingers using photoplethysmography and electrocardiography. Each subject received 3 heat-induced pain stimuli using a Temperature-Sensory Analyzer thermode block to apply a controlled, increasing temperature from 32.0 °C to 50.0 °C to the skin. After reaching 50.0 °C, the thermode was immediately cooled down to 32.0 °C. The study population was divided into 2 groups with a time-interval between the stimuli 20s or 60s. The results showed a significant (p  Heat-induced pain causes a decrease of PTT and PWA. Consequently, it is expected that, in the future, PTT and PWA may be applied as objective indicators of pain, either beside the standard self-report test, or when self-report testing is impossible.

Arterial blood oxygen saturation during blood pressure cuff-induced hypoperfusion

International Nuclear Information System (INIS)

Kyriacou, P A; Shafqat, K; Pal, S K

2007-01-01

Pulse oximetry has been one of the most significant technological advances in clinical monitoring in the last two decades. Pulse oximetry is a non-invasive photometric technique that provides information about the arterial blood oxygen saturation (SpO 2 ) and heart rate, and has widespread clinical applications. When peripheral perfusion is poor, as in states of hypovolaemia, hypothermia and vasoconstriction, oxygenation readings become unreliable or cease. The problem arises because conventional pulse oximetry sensors must be attached to the most peripheral parts of the body, such as finger, ear or toe, where pulsatile flow is most easily compromised. Pulse oximeters estimate arterial oxygen saturation by shining light at two different wavelengths, red and infrared, through vascular tissue. In this method the ac pulsatile photoplethysmographic (PPG) signal associated with cardiac contraction is assumed to be attributable solely to the arterial blood component. The amplitudes of the red and infrared ac PPG signals are sensitive to changes in arterial oxygen saturation because of differences in the light absorption of oxygenated and deoxygenated haemoglobin at these two wavelengths. From the ratios of these amplitudes, and the corresponding dc photoplethysmographic components, arterial blood oxygen saturation (SpO 2 ) is estimated. Hence, the technique of pulse oximetry relies on the presence of adequate peripheral arterial pulsations, which are detected as photoplethysmographic (PPG) signals. The aim of this study was to investigate the effect of pressure cuff-induced hypoperfusion on photoplethysmographic signals and arterial blood oxygen saturation using a custom made finger blood oxygen saturation PPG/SpO 2 sensor and a commercial finger pulse oximeter. Blood oxygen saturation values from the custom oxygen saturation sensor and a commercial finger oxygen saturation sensor were recorded from 14 healthy volunteers at various induced brachial pressures. Both pulse

Arterial blood oxygen saturation during blood pressure cuff-induced hypoperfusion

Science.gov (United States)

Kyriacou, P. A.; Shafqat, K.; Pal, S. K.

2007-10-01

Pulse oximetry has been one of the most significant technological advances in clinical monitoring in the last two decades. Pulse oximetry is a non-invasive photometric technique that provides information about the arterial blood oxygen saturation (SpO2) and heart rate, and has widespread clinical applications. When peripheral perfusion is poor, as in states of hypovolaemia, hypothermia and vasoconstriction, oxygenation readings become unreliable or cease. The problem arises because conventional pulse oximetry sensors must be attached to the most peripheral parts of the body, such as finger, ear or toe, where pulsatile flow is most easily compromised. Pulse oximeters estimate arterial oxygen saturation by shining light at two different wavelengths, red and infrared, through vascular tissue. In this method the ac pulsatile photoplethysmographic (PPG) signal associated with cardiac contraction is assumed to be attributable solely to the arterial blood component. The amplitudes of the red and infrared ac PPG signals are sensitive to changes in arterial oxygen saturation because of differences in the light absorption of oxygenated and deoxygenated haemoglobin at these two wavelengths. From the ratios of these amplitudes, and the corresponding dc photoplethysmographic components, arterial blood oxygen saturation (SpO2) is estimated. Hence, the technique of pulse oximetry relies on the presence of adequate peripheral arterial pulsations, which are detected as photoplethysmographic (PPG) signals. The aim of this study was to investigate the effect of pressure cuff-induced hypoperfusion on photoplethysmographic signals and arterial blood oxygen saturation using a custom made finger blood oxygen saturation PPG/SpO2 sensor and a commercial finger pulse oximeter. Blood oxygen saturation values from the custom oxygen saturation sensor and a commercial finger oxygen saturation sensor were recorded from 14 healthy volunteers at various induced brachial pressures. Both pulse

How important is the recommended slow cuff pressure deflation rate for blood pressure measurement?

Science.gov (United States)

Zheng, Dingchang; Amoore, John N; Mieke, Stephan; Murray, Alan

2011-10-01

Cuff pressure deflation rate influences blood pressure (BP) measurement. However, there is little quantitative clinical evidence on its effect. Oscillometric pulses recorded from 75 subjects at the recommended deflation rate of 2-3 mmHg per second were analyzed. Some pulses were removed to realize six faster rates (2-7 times faster than the original). Systolic, diastolic, and mean arterial blood pressures (SBP, DBP, MAP) were determined from the original and six reconstructed oscillometric waveforms. Manual measurement was based on the appearance of oscillometric pulse peaks, and automatic measurement on two model envelopes (linear and polynomial) fitted to the sequence of oscillometric pulse amplitudes. The effects of deflation rate on BP determination and within-subject BP variability were analyzed. For SBP and DBP determined from the manual measurement, different deflation rates resulted in significant changes (both p deflation rate effect (all p > 0.3). Faster deflation increased the within-subject BP variability (all p deflation rate, and for the automatic model-based techniques, the deflation rate had little effect.

Measurement of the pressure pulse from a detonating explosive

International Nuclear Information System (INIS)

Bourne, N K; Milne, A M; Biers, R A

2005-01-01

A series of experiments has been carried out to determine the pressure pulse exiting from a polymethylmethacrylate (PMMA) plate, of varying thickness, subject to the shock pulse exerted by a detonating charge of fixed mass. This calibration will define a new donor explosive and inert gap material for use in one of the qualification tests for energetic materials, the large scale gap test. The peak pressure was recorded on the central axis of the attenuator using calibrated piezoresistive manganin gauges as a function of the quantity of PMMA applied to the output of the donor charge. The stress history within the PMMA was measured as a function of run distance and the peak pressure plotted against thickness as a calibration. The shock front was known to have curvature and a measurement of this was attempted. The behaviour of the transmitted shock at small gap thicknesses was shown to be anomalous since the front was partially in a reactive and partially within an inert medium

Study on the mode-transition of nanosecond-pulsed dielectric barrier discharge between uniform and filamentary by controlling pressures and pulse repetition frequencies

Science.gov (United States)

Yu, Sizhe; Lu, Xinpei

2016-09-01

We investigate the temporally resolved evolution of the nanosecond pulsed dielectric barrier discharge (DBD) in a moderate 6mm gap under various pressures and pulse repetition frequencies (PRFs) by intensified charge-coupled device (ICCD) images, using synthetic air and its components oxygen and nitrogen. It is found that the pressures are very different when the DBD mode transits between uniform and filamentary in air, oxygen, and nitrogen. The PRFs can also obviously affect the mode-transition. The transition mechanism in the pulsed DBD is not Townsend-to-streamer, which is dominant in the traditional alternating-voltage DBDs. The pulsed DBD in a uniform mode develops in the form of plane ionization wave, due to overlap of primary avalanches, while the increase in pressure disturbs the overlap and DBD develops in streamer instead, corresponding to the filamentary mode. Increasing the initiatory electron density by pre-ionization methods may contribute to discharge uniformity at higher pressures. We also find that the dependence of uniformity upon PRF is non-monotonic.

Coherent combs in ionization by intense and short laser pulses

Energy Technology Data Exchange (ETDEWEB)

Krajewska, K., E-mail: Katarzyna.Krajewska@fuw.edu.pl [Institute of Theoretical Physics, Faculty of Physics, University of Warsaw, Pasteura 5, 02-093 Warszawa (Poland); Department of Physics and Astronomy, University of Nebraska, Lincoln, NE 68588-0299 (United States); Kamiński, J.Z., E-mail: Jerzy.Kaminski@fuw.edu.pl [Institute of Theoretical Physics, Faculty of Physics, University of Warsaw, Pasteura 5, 02-093 Warszawa (Poland)

2016-03-22

Photoionization of positive ions by a train of intense, short laser pulses is investigated within the relativistic strong field approximation, using the velocity gauge. The formation of broad peak structures in the high-energy domain of photoelectrons is observed and interpreted. The emergence of coherent photoelectron energy combs within these structures is demonstrated, and it is interpreted as the consequence of the Fraunhofer-type interference/diffraction of probability amplitudes of ionization from individual pulses comprising the train. Extensions to the coherent angular combs are also studied, and effects related to the radiation pressure are presented. - Highlights: • We develop relativistic Strong-Field Approximation for ionization by intense and short laser pulses of arbitrary spectral compositions. • We show that the consistent interpretation of results is provided by the Keldysh-type saddle point analysis of probability amplitudes. • We derive a general Fraunhofer-type interference/diffraction formula for finite train of pulses. • We study the coherent combs in photoelectron probability distributions.

Measurements of acoustic pressure at high amplitudes and intensities

International Nuclear Information System (INIS)

Crum, L A; Bailey, M R; Kaczkowski, P; McAteer, J A; Pishchalnikov, Y A; Sapozhnikov, O A

2004-01-01

In our research group, we desire measurements of the large pressure amplitudes generated by the shock waves used in shock wave lithotripsy (SWL) and the large acoustic intensities used in High Intensity Focused Ultrasound (HIFU). Conventional piezoelectric or PVDF hydrophones can not be used for such measurements as they are damaged either by cavitation, in SWL applications, or heat, in HIFU applications. In order to circumvent these difficulties, we have utilized optical fiber hydrophones in SWL that do not cavitate, and small glass probes and a scattering technique for measurements of large HIFU intensities. Descriptions of these techniques will be given as well as some typical data

A 900-channel coincidence pulse-amplitude analyser; Selecteur d'amplitudes d'impulsions a coincidence a trois dimensions; Devyatisotkanal'nyj amplitudnyj analizator impul'sov sovpadeniya; Analizador de amplitud de impulsos de coincidencia con 900 canales

Energy Technology Data Exchange (ETDEWEB)

Alexander, T K; Robinson, L B [Atomic Energy of Canada Limited, Chalk River, Ontario (Canada)

1962-04-15

An analyser designed for correlation studies of pulse-height distributions from two scintillation counters is described. The analyser consists of two separate transistorized units; a dual-channel analogue-to-digital encoder and a 900-channel, 2{sup 16}-per-channel capacity ferrite-core store. The display and control unit for the instrument is separate and can be situated away from the analyser. The analysis mode of operation for coincident pulses on the A and B inputs of the encoder can be selected to be 30 by 30, 100 by 9 or 300 channels by 3 distributions. In the last two modes the base lines and the widths of the pulse-amplitude ''windows'' on distribution A can be selected by the operator. With 100 channels for pulse-amplitude analysis, eight ''windows'' in distribution A define eight groups of 100 channels for the B distributions. In this case we have, in effect, one 100-channel analyser for distribution A and eight separate 100-channel analysers to which B can be routed. A description of the basic circuits of the encoder and the logic of the store and display units is given. (author) [French] Le memoire decrit un selecteur concu pour etudier la correlation des distributions en amplitude des impulsions fournies par deux compteurs a scintillations. L'analyseur se compose de deux parties distinctes transistorisees: un codeur analogique/numerique a deux voies et une memoire a ferrites, a 900 canaux d'une capacite de 2{sup 16} par canal. Les tableaux d'enregistrement et les commandes de l'appareil forment un element autonome qui peut etre installe a une certaine distance du selecteur. Pour l'analyse des impulsions de coincidence aux entrees A et B du codeur, on peut combiner les canaux de trois manieres differentes: 30 x 30, 100 x 9 ou 300 x 3. Dans les deux derniers cas, l'operateur peut choisir les lignes de base et la largeur des des amplitudes d'impulsion pour la distribution A. Lorsque l'analyse de l'amplitude d'impulsion se fait avec 100 canaux

Piston cylinder cell for high pressure ultrasonic pulse echo measurements

Energy Technology Data Exchange (ETDEWEB)

Kepa, M. W., E-mail: mkepa@staffmail.ed.ac.uk; Huxley, A. D. [SUPA, Centre for Science at Extreme Conditions and School of Physics and Astronomy, University of Edinburgh, Edinburgh EH9 3JZ (United Kingdom); Ridley, C. J.; Kamenev, K. V. [Centre for Science at Extreme Conditions and School of Engineering, University of Edinburgh, Edinburgh EH9 3FD (United Kingdom)

2016-08-15

Ultrasonic techniques such as pulse echo, vibrating reed, or resonant ultrasound spectroscopy are powerful probes not only for studying elasticity but also for investigating electronic and magnetic properties. Here, we report on the design of a high pressure ultrasonic pulse echo apparatus, based on a piston cylinder cell, with a simplified electronic setup that operates with a single coaxial cable and requires sample lengths of mm only. The design allows simultaneous measurements of ultrasonic velocities and attenuation coefficients up to a pressure of 1.5 GPa. We illustrate the performance of the cell by probing the phase diagram of a single crystal of the ferromagnetic superconductor UGe{sub 2}.

Full-field wrist pulse signal acquisition and analysis by 3D Digital Image Correlation

Science.gov (United States)

Xue, Yuan; Su, Yong; Zhang, Chi; Xu, Xiaohai; Gao, Zeren; Wu, Shangquan; Zhang, Qingchuan; Wu, Xiaoping

2017-11-01

Pulse diagnosis is an essential part in four basic diagnostic methods (inspection, listening, inquiring and palpation) in traditional Chinese medicine, which depends on longtime training and rich experience, so computerized pulse acquisition has been proposed and studied to ensure the objectivity. To imitate the process that doctors using three fingertips with different pressures to feel fluctuations in certain areas containing three acupoints, we established a five dimensional pulse signal acquisition system adopting a non-contacting optical metrology method, 3D digital image correlation, to record the full-field displacements of skin fluctuations under different pressures. The system realizes real-time full-field vibration mode observation with 10 FPS. The maximum sample frequency is 472 Hz for detailed post-processing. After acquisition, the signals are analyzed according to the amplitude, pressure, and pulse wave velocity. The proposed system provides a novel optical approach for digitalizing pulse diagnosis and massive pulse signal data acquisition for various types of patients.

Integrated experimental test program on waterhammer pressure pulses and associated structural responses within a feedwater sparger

Energy Technology Data Exchange (ETDEWEB)

Nurkkala, P.; Hoikkanen, J. [Imatran Voima Oy, Vantaa (Finland)

1997-12-31

This paper describes the methods and systems as utilized in an integrated experimental thermohydraulic/mechanics analysis test program on waterhammer pressure pulses within a revised feedwater sparger of a Loviisa generation VVER-440-type reactor. This program was carried out in two stages: (1) measurements with a strictly limited set of operating parameters at Loviisa NPP, and (2) measurements with the full set of operating parameters on a test article simulating the revised feedwater sparger. The experiments at Loviisa NPS served as an invaluable source of information on the nature of waterhammer pressure pulses and structural responses. These tests thus helped to set the objectives and formulate the concept for series of tests on a test article to study the water hammer phenomena. The heavily instrumented full size test article of a steam generator feedwater sparger was placed within a pressure vessel simulating the steam generator. The feedwater sparger was subjected to the full range of operating parameters which were to result in waterhammer pressure pulse trains of various magnitudes and duration. Two different designs of revised feedwater sparger were investigated (i.e. `grounded` and `with goose neck`). The following objects were to be met within this program: (1) establish the thermohydraulic parameters that facilitate the occurrence of water hammer pressure pulses, (2) provide a database for further analysis of the pressure pulse phenomena, (3) establish location and severity of these water hammer pressure pulses, (4) establish the structural response due to these pressure pulses, (5) provide input data for structural integrity analysis. (orig.). 3 refs.

Integrated experimental test program on waterhammer pressure pulses and associated structural responses within a feedwater sparger

International Nuclear Information System (INIS)

Nurkkala, P.; Hoikkanen, J.

1997-01-01

This paper describes the methods and systems as utilized in an integrated experimental thermohydraulic/mechanics analysis test program on waterhammer pressure pulses within a revised feedwater sparger of a Loviisa generation VVER-440-type reactor. This program was carried out in two stages: (1) measurements with a strictly limited set of operating parameters at Loviisa NPP, and (2) measurements with the full set of operating parameters on a test article simulating the revised feedwater sparger. The experiments at Loviisa NPS served as an invaluable source of information on the nature of waterhammer pressure pulses and structural responses. These tests thus helped to set the objectives and formulate the concept for series of tests on a test article to study the water hammer phenomena. The heavily instrumented full size test article of a steam generator feedwater sparger was placed within a pressure vessel simulating the steam generator. The feedwater sparger was subjected to the full range of operating parameters which were to result in waterhammer pressure pulse trains of various magnitudes and duration. Two different designs of revised feedwater sparger were investigated (i.e. 'grounded' and 'with goose neck'). The following objects were to be met within this program: (1) establish the thermohydraulic parameters that facilitate the occurrence of water hammer pressure pulses, (2) provide a database for further analysis of the pressure pulse phenomena, (3) establish location and severity of these water hammer pressure pulses, (4) establish the structural response due to these pressure pulses, (5) provide input data for structural integrity analysis. (orig.)

Integrated experimental test program on waterhammer pressure pulses and associated structural responses within a feedwater sparger

Energy Technology Data Exchange (ETDEWEB)

Nurkkala, P; Hoikkanen, J [Imatran Voima Oy, Vantaa (Finland)

1998-12-31

This paper describes the methods and systems as utilized in an integrated experimental thermohydraulic/mechanics analysis test program on waterhammer pressure pulses within a revised feedwater sparger of a Loviisa generation VVER-440-type reactor. This program was carried out in two stages: (1) measurements with a strictly limited set of operating parameters at Loviisa NPP, and (2) measurements with the full set of operating parameters on a test article simulating the revised feedwater sparger. The experiments at Loviisa NPS served as an invaluable source of information on the nature of waterhammer pressure pulses and structural responses. These tests thus helped to set the objectives and formulate the concept for series of tests on a test article to study the water hammer phenomena. The heavily instrumented full size test article of a steam generator feedwater sparger was placed within a pressure vessel simulating the steam generator. The feedwater sparger was subjected to the full range of operating parameters which were to result in waterhammer pressure pulse trains of various magnitudes and duration. Two different designs of revised feedwater sparger were investigated (i.e. `grounded` and `with goose neck`). The following objects were to be met within this program: (1) establish the thermohydraulic parameters that facilitate the occurrence of water hammer pressure pulses, (2) provide a database for further analysis of the pressure pulse phenomena, (3) establish location and severity of these water hammer pressure pulses, (4) establish the structural response due to these pressure pulses, (5) provide input data for structural integrity analysis. (orig.). 3 refs.

Abdominal Obesity Is Characterized by Higher Pulse Pressure: Possible Role of Free Triiodothyronine

Directory of Open Access Journals (Sweden)

Giovanni De Pergola

2012-01-01

Full Text Available Objective. This study examined whether obesity is characterized by higher 24 h mean pulse pressure (24 h mean SBP-24 h mean DBP and whether free thyroid hormones (FT3 and FT4 have a relationship with 24 h mean pulse pressure. Methods. A total of 231 euthyroid overweight and obese patients, 103 women and 128 men, aged 18–68 yrs, normotensive ( or with recently developed hypertension (, never treated with antihypertensive drugs, were investigated. Fasting insulin, TSH, FT3, FT4, glucose, and lipid serum concentrations were measured. Waist circumference was measured as an indirect parameter of central fat accumulation. Ambulatory blood pressure monitoring (ABPM was performed. Results. 24 h mean pulse pressure (PP showed a significant positive correlation with BMI (, waist circumference (, and FT3 ( and insulin serum levels (. When a multivariate analysis was performed, and 24 h PP was considered as the dependent variable, and waist circumference, FT3, insulin, male sex, and age as independent parameters, 24 h mean PP maintained a significant association only with waist circumference ( and FT3 levels (. Conclusion. Our results suggest that FT3 per se may contribute to higher pulse pressure in obese subjects.

Systolic Blood Pressure Accuracy Enhancement in the Electronic Palpation Method Using Pulse Waveform

National Research Council Canada - National Science Library

Sorvoja, H

2001-01-01

.... Systolic pressure errors were defined and correlations with other specific values, like pressure rise time, pulse wave velocity, systolic pressure, augmentation, arm circumference and body mass index were calculated...

Repetitively pulsed UV radiation source based on a run-away electron preionised diffuse discharge in nitrogen

Energy Technology Data Exchange (ETDEWEB)

Baksht, E Kh; Burachenko, A G; Lomaev, M I; Panchenko, A N; Tarasenko, V F [Institute of High Current Electronics, Siberian Branch, Russian Academy of Sciences, Tomsk (Russian Federation)

2015-04-30

An extended repetitively pulsed source of spontaneous UV radiation is fabricated, which may also be used for producing laser radiation. Voltage pulses with an incident wave amplitude of up to 30 kV, a half-amplitude duration of ∼4 ns and a rise time of ∼2.5 ns are applied to a gap with a nonuniform electric field. For an excitation region length of 35 cm and a nitrogen pressure of 30 – 760 Torr, a diffusive discharge up to a pulse repetition rate of 2 kHz is produced without using an additional system for gap preionisation. An investigation is made of the plasma of the run-away electron preionised diffuse discharge. Using a CCD camera it is found that the dense diffused plasma fills the gap in a time shorter than 1 ns. X-ray radiation is recorded from behind the foil anode throughout the pressure range under study; a supershort avalanche electron beam is recorded by the collector electrode at pressures below 100 Torr. (laser applications and other topics in quantum electronics)

Elevated pulse pressure is associated with hemolysis, proteinuria and chronic kidney disease in sickle cell disease.

Directory of Open Access Journals (Sweden)

Enrico M Novelli

Full Text Available A seeming paradox of sickle cell disease is that patients do not suffer from a high prevalence of systemic hypertension in spite of endothelial dysfunction, chronic inflammation and vasculopathy. However, some patients do develop systolic hypertension and increased pulse pressure, an increasingly recognized major cardiovascular risk factor in other populations. Hence, we hypothesized that pulse pressure, unlike other blood pressure parameters, is independently associated with markers of hemolytic anemia and cardiovascular risk in sickle cell disease. We analyzed the correlates of pulse pressure in patients (n  =  661 enrolled in a multicenter international sickle cell trial. Markers of hemolysis were analyzed as independent variables and as a previously validated hemolytic index that includes multiple variables. We found that pulse pressure, not systolic, diastolic or mean arterial pressure, independently correlated with high reticulocyte count (beta  =  2.37, p  =  0.02 and high hemolytic index (beta  =  1.53, p = 0.002 in patients with homozygous sickle cell disease in two multiple linear regression models which include the markers of hemolysis as independent variables or the hemolytic index, respectively. Pulse pressure was also independently associated with elevated serum creatinine (beta  =  3.21, p  =  0.02, and with proteinuria (beta  =  2.52, p  =  0.04. These results from the largest sickle cell disease cohort to date since the Cooperative Study of Sickle Cell Disease show that pulse pressure is independently associated with hemolysis, proteinuria and chronic kidney disease. We propose that high pulse pressure may be a risk factor for clinical complications of vascular dysfunction in sickle cell disease. Longitudinal and mechanistic studies should be conducted to confirm these hypotheses.

Coronary oscillatory flow amplitude is more affected by perfusion pressure than ventricular pressure.

Science.gov (United States)

Krams, R; Sipkema, P; Westerhof, N

1990-06-01

In this study on the isolated, maximally vasodilated, blood-perfused cat heart we investigated the relation between left ventricular developed pressure (delta Piv) and coronary oscillatory flow amplitude (diastolic minus systolic flow, delta F) at different levels of constant perfusion pressure (Pp). We hypothesized that the effect of cardiac contraction on the phasic flow results from the changing elastic properties of cardiac muscle. The coronary vessel compartment can, as can the left ventricular lumen compartment, be described by a time-varying elastance. This concept predicts that the effect of left ventricular pressure on delta F is small, whereas the effect of Pp is considerable. Both the waterfall model and the intramyocardial pump model predict the inverse. The relation between delta Piv and delta F at a Pp of 10 kPa is delta F = (4.71 +/- 3.08).delta Piv + 337 +/- 75 (slope in ml.min-1.100 g-1.kPa-1 and intercept in ml.min-1.100 g-1; n = 7); the relation between (constant levels of) Pp and delta F at a constant delta Piv of 10 kPa is delta F = 51.Pp + 211 (slope in ml.min-1.100 g-1.kPa-1 and intercept in ml.min-1.100 g-1; n = 6). The differences in slope are best predicted by the time-varying elastance concept.

Morning pulse pressure is associated more strongly with elevated albuminuria than systolic blood pressure in patients with type 2 diabetes mellitus: post hoc analysis of a cross-sectional multicenter study.

Science.gov (United States)

Ushigome, Emi; Fukui, Michiaki; Hamaguchi, Masahide; Matsumoto, Shinobu; Mineoka, Yusuke; Nakanishi, Naoko; Senmaru, Takafumi; Yamazaki, Masahiro; Hasegawa, Goji; Nakamura, Naoto

2013-09-01

Recently, focus has been directed toward pulse pressure as a potentially independent risk factor for micro- and macrovascular disease. This study was designed to examine the relationship between pulse pressure taken at home and elevated albuminuria in patients with type 2 diabetes. This study is a post hoc analysis of a cross-sectional multicenter study. Home blood pressure measurements were performed for 14 consecutive days in 858 patients with type 2 diabetes. We investigated the relationship between systolic blood pressure or pulse pressure in the morning or in the evening and urinary albumin excretion using univariate and multivariate analyses. Furthermore, we measured area under the receiver-operating characteristic curve (AUC) to compare the ability to identify elevated albuminuria, defined as urinary albumin excretion equal to or more than 30 mg/g creatinine, of systolic blood pressure or pulse pressure. Morning systolic blood pressure (β=0.339, Ppressure (β=0.378, PAUC for elevated albuminuria in morning systolic blood pressure and morning pulse pressure were 0.668 (0.632-0.705; PAUC of morning pulse pressure was significantly greater than that of morning systolic blood pressure (P=0.040). Our findings implicate that morning pulse pressure is associated with elevated albuminuria in patients with type 2 diabetes, which suggests that lowering morning pulse pressure could prevent the development and progression of diabetic nephropathy. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

Differing prognostic value of pulse pressure in patients with heart failure with reduced or preserved ejection fraction

DEFF Research Database (Denmark)

Jackson, Colette E; Castagno, Davide; Maggioni, Aldo P

2015-01-01

) and 5008 with HF-PEF (828 deaths). Pulse pressure was analysed in quintiles in a multivariable model adjusted for the previously reported Meta-Analysis Global Group in Chronic Heart Failure prognostic variables. Heart failure and reduced ejection fraction patients in the lowest pulse pressure quintile had...... in patients with HF-PEF [ejection fraction (EF) ≥ 50%] and HF-REF. METHODS AND RESULTS: Data from 22 HF studies were examined. Preserved left ventricular ejection fraction (LVEF) was defined as LVEF ≥ 50%. All-cause mortality at 3 years was evaluated in 27 046 patients: 22 038 with HF-REF (4980 deaths......AIMS: Low pulse pressure is a marker of adverse outcome in patients with heart failure (HF) and reduced ejection fraction (HF-REF) but the prognostic value of pulse pressure in patients with HF and preserved ejection fraction (HF-PEF) is unknown. We examined the prognostic value of pulse pressure...

Measurement of amplitude fluctuations in a rapid response photomultiplier

International Nuclear Information System (INIS)

Raimbault, P.

1961-01-01

In order to measure amplitude fluctuations in a rapid response photomultiplier, two independent random variables are introduced which determine the shape of the anode pulse. The energy of each pulse, which depends directly on the gain and the variance, is the first variable; amplitude fluctuations, functions of the first variable, depend as well on the pulse width which in turn constitutes the second variable. The results obtained on the variations of the maximum impulse, using a steep-edged pulse broadening circuit, and those obtained on the statistical variations of the gain, are compared to show that the variance relative to the maximum amplitude of the signal is greater than that of the gain. Within the limits of these fluctuations are shown the contribution of the secondary emission coefficient of the first dynode, and that of the mean secondary emission coefficient of the multiplier. (author) [fr

Numerical investigation of the effect of driving voltage pulse shapes on the characteristics of low-pressure argon dielectric barrier discharge

International Nuclear Information System (INIS)

Eslami, E.; Barjasteh, A.; Morshedian, N.

2015-01-01

In this work, we numerically compare the effect of a sinusoidal, triangular, and rectangular pulsed voltage profile on the calculated particle production, electric current, and gas voltage in a dielectric barrier discharge. The total argon gas pressure of 400 Pa, the distance between dielectrics of 5 mm, the dielectric thickness of 0.7 mm, and the temperature of T = 300 K were considered as input parameters. The different driving voltage pulse shapes (triangular, rectangular, and sinusoidal) are considered as applied voltage with a frequency of 7 kHz and an amplitude of 700 V peak to peak. It is shown that applying a rectangular voltage, as compared with a sinusoidal or triangle voltage, increases the current peak, while the peak width is decreased. Higher current density is related to high production of charged particles, which leads to the generation of some highly active species, such as Ar* (4s level), and Ar** (4p level) in the gap

Multi-Pulsed High Hydrostatic Pressure Treatment of Foods

Directory of Open Access Journals (Sweden)

Sencer Buzrul

2015-05-01

Full Text Available Multi-pulsed high hydrostatic pressure (mpHHP treatment of foods has been investigated for more than two decades. It was reported that the mpHHP treatment, with few exceptions, is more effective than the classical or single-pulsed HHP (spHHP treatment for inactivation of microorganisms in fruit juice, dairy products, liquid whole egg, meat products, and sea foods. Moreover, the mpHHP treatment could be also used to inactivate enzymes in foods and to increase the shelf-life of foods. The effects of the mpHHP treatment of foods are summarized and the differences between the mpHHP and spHHP are also emphasized.

Emission of ultrashort electromagnetic pulses from electron bunches formed and accelerated by laser beams with tilted amplitude fronts

International Nuclear Information System (INIS)

Galkin, A.L.; Korobkin, V.V.; Romanovsky, M.Yu.; Shiryaev, O.B.; Trofimov, V.A.

2013-01-01

The dynamics of an electron in a standing wave generated by a pair of counterpropagating linearly polarized relativistically intense laser pulses and the emission of electromagnetic radiation by the electron are analyzed. The pulses are assumed to have tilted amplitude fronts and asymmetric focal spots. The analysis of the dynamics is performed by solving numerically the Newton equation with the corresponding Lorentz force, and the emission of radiation is simulated based on the Lienard-Wiechert potentials. The electrons are accelerated by the direct action of the standing wave field and are shown to form a small short bunch. For relativistic intensities, the energies gained by the electrons reach several GeV. It is demonstrated that the radiation emitted by the electrons in the bunch is a single electromagnetic pulse confined to a narrow solid angle and having an attosecond duration. (copyright 2013 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

Measurement of amplitude fluctuations in a rapid response photomultiplier; Mesure des fluctuations d'amplitude d'un photo multiplicateur a reponse rapide

Energy Technology Data Exchange (ETDEWEB)

Raimbault, P [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires

1961-07-01

In order to measure amplitude fluctuations in a rapid response photomultiplier, two independent random variables are introduced which determine the shape of the anode pulse. The energy of each pulse, which depends directly on the gain and the variance, is the first variable; amplitude fluctuations, functions of the first variable, depend as well on the pulse width which in turn constitutes the second variable. The results obtained on the variations of the maximum impulse, using a steep-edged pulse broadening circuit, and those obtained on the statistical variations of the gain, are compared to show that the variance relative to the maximum amplitude of the signal is greater than that of the gain. Within the limits of these fluctuations are shown the contribution of the secondary emission coefficient of the first dynode, and that of the mean secondary emission coefficient of the multiplier. (author) [French] Pour etudier les fluctuations d'amplitude d'un photomultiplicateur a reponse rapide, on introduit deux variables aleatoires independantes qui determinent la forme de l'impulsion anodique. L'energie de chaque impulsion, directement fonction du gain et de sa variance, est la premiere variable; les fluctuations d'amplitude, fonctions de la premiere variable, dependent egalement de la largeur de l'impulsion qui, elle, constitue la deuxieme variable. Les resultats obtenus sur les variations de l'amplitude maximale, a l'aide d'un circuit elargisseur d'impulsions a front raide, et les resultats des variations statistiques du gain sont compares pour mettre en evidence le fait que la variance relative a l'amplitude maximale du signal est plus grande que celle du gain. Dans la mesure de ces fluctuations, sont mises en evidence la contribution du coefficient d'emission secondaire de la premiere dynode et celle du coefficient d'emission secondaire moyen du multiplicateur. (auteur)

Unconstrained pulse pressure monitoring for health management using hetero-core fiber optic sensor.

Science.gov (United States)

Nishiyama, Michiko; Sonobe, Masako; Watanabe, Kazuhiro

2016-09-01

In this paper, we present a pulse pressure waveform sensor that does not constrain a wearer's daily activity; the sensor uses hetero-core fiber optics. Hetero-core fiber sensors have been found to be sensitive to moderate bending. To detect minute pulse pressure changes from the radial artery at the wrist, we devised a fiber sensor arrangement using three-point bending supports. We analyzed and evaluated the measurement validity using wavelet transformation, which is well-suited for biological signal processing. It was confirmed that the detected pulse waveform had a fundamental mode frequency of around 1.25 Hz over the time-varying waveform. A band-pass filter with a range of frequencies from 0.85 to 1.7 Hz was used to pick up the fundamental mode. In addition, a high-pass filter with 0.85 Hz frequency eliminated arm motion artifacts; consequently, we achieved high signal-to-noise ratio. For unrestricted daily health management, it is desirable that pulse pressure monitoring can be achieved by simply placing a device on the hand without the sensor being noticed. Two types of arrangements were developed and demonstrated in which the pulse sensors were either embedded in a base, such as an armrest, or in a wearable device. A wearable device without cuff pressure using a sensitivity-enhanced fiber sensor was successfully achieved with a sensitivity of 0.07-0.3 dB with a noise floor lower than 0.01 dB for multiple subjects.

Arterial blood oxygen saturation during blood pressure cuff-induced hypoperfusion

Energy Technology Data Exchange (ETDEWEB)

Kyriacou, P A [School of Engineering and Mathematical Sciences, City University, London EC1V 0HB (United Kingdom); Shafqat, K [School of Engineering and Mathematical Sciences, City University, London EC1V 0HB (United Kingdom); Pal, S K [St Andrew' s Centre for Plastic Surgery and Burns, Broomfield Hospital, Chelmsford, CM1 7ET (United Kingdom)

2007-10-15

Pulse oximetry has been one of the most significant technological advances in clinical monitoring in the last two decades. Pulse oximetry is a non-invasive photometric technique that provides information about the arterial blood oxygen saturation (SpO{sub 2}) and heart rate, and has widespread clinical applications. When peripheral perfusion is poor, as in states of hypovolaemia, hypothermia and vasoconstriction, oxygenation readings become unreliable or cease. The problem arises because conventional pulse oximetry sensors must be attached to the most peripheral parts of the body, such as finger, ear or toe, where pulsatile flow is most easily compromised. Pulse oximeters estimate arterial oxygen saturation by shining light at two different wavelengths, red and infrared, through vascular tissue. In this method the ac pulsatile photoplethysmographic (PPG) signal associated with cardiac contraction is assumed to be attributable solely to the arterial blood component. The amplitudes of the red and infrared ac PPG signals are sensitive to changes in arterial oxygen saturation because of differences in the light absorption of oxygenated and deoxygenated haemoglobin at these two wavelengths. From the ratios of these amplitudes, and the corresponding dc photoplethysmographic components, arterial blood oxygen saturation (SpO{sub 2}) is estimated. Hence, the technique of pulse oximetry relies on the presence of adequate peripheral arterial pulsations, which are detected as photoplethysmographic (PPG) signals. The aim of this study was to investigate the effect of pressure cuff-induced hypoperfusion on photoplethysmographic signals and arterial blood oxygen saturation using a custom made finger blood oxygen saturation PPG/SpO{sub 2} sensor and a commercial finger pulse oximeter. Blood oxygen saturation values from the custom oxygen saturation sensor and a commercial finger oxygen saturation sensor were recorded from 14 healthy volunteers at various induced brachial pressures

Impact of non-white noises in pulse amplitude measurements: a time-domain approach

International Nuclear Information System (INIS)

Pullia, A.

1998-01-01

The contribution of the 1/f-noise to the spectral line broadening in pulse amplitude measurements is derived with a time-domain analysis. The known time-domain relationships which provide the contributions of the series and parallel white noises are generalised for the case of 1/f and other typical non-white noises, by using the fractional derivative of either the system impulse response (time-invariant linear filters) or its weight function folded (time-variant linear filters). It is shown that a time-domain approach is also effective to determine the contribution of Lorentzian noises. A simple rule suitable to derive numerically the fractional derivative is given, which permits to calculate the effect of non-white noises even when the filter impulse response is not known analytically but only in sampled form. (orig.)

Quasi-periodic Pulse Amplitude Modulation in the Accreting Millisecond Pulsar IGR J00291+5934

Energy Technology Data Exchange (ETDEWEB)

Bult, Peter [Astrophysics Science Division, NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Doesburgh, Marieke van; Klis, Michiel van der [Anton Pannekoek Institute, University of Amsterdam, Postbus 94249, 1090 GE Amsterdam (Netherlands)

2017-08-20

We introduce a new method for analyzing the aperiodic variability of coherent pulsations in accreting millisecond X-ray pulsars (AMXPs). Our method involves applying a complex frequency correction to the time-domain light curve, allowing for the aperiodic modulation of the pulse amplitude to be robustly extracted in the frequency domain. We discuss the statistical properties of the resulting modulation spectrum and show how it can be correlated with the non-pulsed emission to determine if the periodic and aperiodic variability are coupled processes. Using this method, we study the 598.88 Hz coherent pulsations of the AMXP IGR J00291+5934 as observed with the Rossi X-ray Timing Explorer and XMM-Newton . We demonstrate that our method easily confirms the known coupling between the pulsations and a strong 8 mHz quasi-periodic oscillation (QPO) in XMM-Newton observations. Applying our method to the RXTE observations, we further show, for the first time, that the much weaker 20 mHz QPO and its harmonic are also coupled with the pulsations. We discuss the implications of this coupling and indicate how it may be used to extract new information on the underlying accretion process.

Quasi-Periodic Pulse Amplitude Modulation in the Accreting Millisecond Pulsar IGR J00291+5934

Science.gov (United States)

Bult, Peter; van Doesburgh, Marieke; van der Klis, Michiel

2017-01-01

We introduce a new method for analyzing the a periodic variability of coherent pulsations in accreting millisecond X-ray pulsars (AMXPs). Our method involves applying a complex frequency correction to the time-domain lightcurve, allowing for the aperiodic modulation of the pulse amplitude to be robustly extracted in the frequency domain. We discuss the statistical properties of the resulting modulation spectrum and show how it can be correlated with the non-pulsed emission to determine if the periodic and a periodic variability are coupled processes. Using this method, we study the 598.88 Hz coherent pulsations of the AMXP IGR J00291+5934 as observed with the Rossi X-ray Timing Explorer and XMM-Newton. We demonstrate that our method easily confirms the known coupling between the pulsations and a strong 8 mHz quasi-periodic oscillation (QPO) in XMM-Newton observations. Applying our method to the RXTE observations, we further show, for the first time, that the much weaker 20 mHz QPO and its harmonic are also coupled with the pulsations. We discuss the implications of this coupling and indicate how it may be used to extract new information on the underlying accretion process.

Effect of high-hydrostatic pressure and moderate-intensity pulsed electric field on plum.

Science.gov (United States)

García-Parra, J; González-Cebrino, F; Delgado-Adámez, J; Cava, R; Martín-Belloso, O; Élez-Martínez, P; Ramírez, R

2018-03-01

Moderate intensity pulse electric fields were applied in plum with the aim to increase bioactive compounds content of the fruit, while high-hydrostatic pressure was applied to preserve the purées. High-hydrostatic pressure treatment was compared with an equivalent thermal treatment. The addition of ascorbic acid during purée manufacture was also evaluated. The main objective of this study was to assess the effects on microorganisms, polyphenoloxidase, color and bioactive compounds of high-hydrostatic pressure, or thermal-processed plum purées made of moderate intensity pulse electric field-treated or no-moderate intensity pulse electric field-treated plums, after processing during storage. The application of moderate intensity pulse electric field to plums slightly increased the levels of anthocyanins and the antioxidant activity of purées. The application of Hydrostatic-high pressure (HHP) increased the levels of bioactive compounds in purées, while the thermal treatment preserved better the color during storage. The addition of ascorbic acid during the manufacture of plum purée was an important factor for the final quality of purées. The color and the bioactive compounds content were better preserved in purées with ascorbic acid. The no inactivation of polyphenoloxidase enzyme with treatments applied in this study affected the stability purées. Probably more intense treatments conditions (high-hydrostatic pressure and thermal treatment) would be necessary to reach better quality and shelf life during storage.

Phylloquinone (vitamin K₁) intake and pulse pressure as a measure of arterial stiffness in older adults.

Science.gov (United States)

Vaccaro, Joan A; Huffman, Fatma G

2013-01-01

This study examined the relationships among ethnicity/race, lifestyle factors, phylloquinone (vitamin K₁) intake, and arterial pulse pressure in a nationally representative sample of older adults from four ethnic/racial groups: non-Hispanic Whites, non-Hispanic Blacks, Mexican Americans, and other Hispanics. This was a cross-sectional study of U.S. representative sample with data from the National Health and Nutrition Examination Surveys, 2007-2008 and 2009-2010 of adults aged 50 years and older (N = 5296). Vitamin K intake was determined by 24-hour recall. Pulse pressure was calculated as the difference between the averages of systolic blood pressure and diastolic blood pressure. Compared to White non-Hispanics, the other ethnic/racial groups were more likely to have inadequate vitamin K₁ intake. Inadequate vitamin K₁ intake was an independent predictor of high arterial pulse pressure. This was the first study that compared vitamin K₁ inadequacy with arterial pulse pressure across ethnicities/races in U.S. older adults. These findings suggest that vitamin K screening may be a beneficial marker for the health of older adults.

AMPLITUDE AND TIME MEASUREMENT ASIC WITH ANALOG DERANDOMIZATION

International Nuclear Information System (INIS)

O CONNOR, P.; DE GERONIMO, G.; KANDASAMY, A.

2002-01-01

We describe a new ASIC for accurate and efficient processing of high-rate pulse signals from highly segmented detectors. In contrast to conventional approaches, this circuit affords a dramatic reduction in data volume through the use of analog techniques (precision peak detectors and time-to-amplitude converters) together with fast arbitration and sequencing logic to concentrate the data before digitization. In operation the circuit functions like a data-driven analog first-in, first-out (FIFO) memory between the preamplifiers and the ADC. Peak amplitudes of pulses arriving at any one of the 32 inputs are sampled, stored, and queued for readout and digitization through a single output port. Hit timing, pulse risetime, and channel address are also available at the output. Prototype chips have been fabricated in 0.35 micron CMOS and tested. First results indicate proper functionality for pulses down to 30 ns peaking time and input rates up to 1.6 MHz/channel. Amplitude accuracy of the peak detect and hold circuit is 0.3% (absolute). TAC accuracy is within 0.3% of full scale. Power consumption is less than 2 mW/channel. Compared with conventional techniques such as track-and-hold and analog memory, this new ASIC will enable efficient pulse height measurement at 20 to 300 times higher rates

Design of a Continuous Blood Pressure Measurement System Based on Pulse Wave and ECG Signals.

Science.gov (United States)

Li, Jian-Qiang; Li, Rui; Chen, Zhuang-Zhuang; Deng, Gen-Qiang; Wang, Huihui; Mavromoustakis, Constandinos X; Song, Houbing; Ming, Zhong

2018-01-01

With increasingly fierce competition for jobs, the pressures on people have risen in recent years, leading to lifestyle and diet disorders that result in significantly higher risks of cardiovascular disease. Hypertension is one of the common chronic cardiovascular diseases; however, mainstream blood pressure measurement devices are relatively heavy. When multiple measurements are required, the user experience and the measurement results may be unsatisfactory. In this paper, we describe the design of a signal collection module that collects pulse waves and electrocardiograph (ECG) signals. The collected signals are input into a signal processing module to filter the noise and amplify the useful physiological signals. Then, we use a wavelet transform to eliminate baseline drift noise and detect the feature points of the pulse waves and ECG signals. We propose the concept of detecting the wave shape associated with an instance, an approach that minimizes the impact of atypical pulse waves on blood pressure measurements. Finally, we propose an improved method for measuring blood pressure based on pulse wave velocity that improves the accuracy of blood pressure measurements by 58%. Moreover, the results meet the american medical instrument promotion association standards, which demonstrate the feasibility of our measurement system.

Plasma wave amplitude measurement created by guided laser wakefield

International Nuclear Information System (INIS)

Wojda, Franck

2010-01-01

The interaction of an intense laser pulse of short duration with a plasma produces a plasma wave with large amplitude in its wake, which is associated with a longitudinal electric field. It can be used to accelerate relativistic electrons injected into the wave to energies in the GeV range over distances of the order of a few centimeters, short compared to acceleration lengths in conventional accelerators. The control of the electron beam characteristics during the acceleration process is fundamental for achieving a usable laser-plasma acceleration stage. The main result of this thesis is the creation and characterization of a plasma wave in a weakly nonlinear regime over a length of several centimeters. Capillary tubes are used to guide the laser beam over these distances, while maintaining a large enough intensity (∼ 10 17 W/cm 2 ). The guided laser beam ionizes the gas in the tube and creates the plasma wave. A diagnostic based on the modification of the laser pulse spectrum was used to determine the amplitude of the plasma wave along the tube. The amplitude of the plasma wave was studied as a function of gas filling pressure, length of the capillary and laser energy. Experimental results are compared; they are in excellent agreement with analytical results and modeling. They show that the electric field associated with the plasma wave is between 1 and 10 GV/m over a length of up to 8 cm. This work has demonstrated the ability to create a controlled plasma wave in a weakly nonlinear regime. (author)

Output Pressure and Pulse-Echo Characteristics of CMUTs as Function of Plate Dimensions

DEFF Research Database (Denmark)

Diederichsen, Søren Elmin; Hansen, Jesper Mark Fly; Engholm, Mathias

2017-01-01

This paper presents an experimental study of the acoustic performance of Capacitive Micromachined Ultrasonic Transducers (CMUTs) as function of plate dimensions. The objective is to increase the output pressure without decreasingthe pulse-echo signal. The CMUTs are fabricated with a LOCOS process......-to-peak output pressure and pulse-echo signal is obtained for the 9.3μm plate, which still has a moderate pulseecho bandwidth of 60%. The 9.3μm plate results in a 1.9 times higher peak-to-peak output pressure and a 3.6 times higherpulse-echo signal compared to the 2μm plate. By adjusting the plate dimensions...

Aluminum oxide films deposited in low pressure conditions by reactive pulsed dc magnetron sputtering

CERN Document Server

Seino, T

2002-01-01

The reactive pulsed dc sputtering technique is widely used for the deposition of oxide films. The operating pressure for sputtering is commonly above 0.13 Pa. In this study, however, aluminum oxide (alumina) films were deposited at operating pressures from 0.06 to 0.4 Pa using a sputtering system equipped with a scanning magnetron cathode and a pulsed dc power supply. The pulsed dc power was found to be useful not only to reduce arcing, but also to sustain the discharge at low pressure. The electrical breakdown field, intrinsic stress, O/Al ratio, refractive index, and surface roughness were investigated. Both a low intrinsic stress and an O/Al ratio around the stoichiometry were required to get the film having a high breakdown field. A low operating pressure of 0.1 Pa was found to provide the necessary stress and O/Al ratio targets. A 50-nm-thick alumina film having a maximum breakdown field of 7.4 MV/cm was obtained.

Dual-modality arterial pulse monitoring system for continuous blood pressure measurement.

Science.gov (United States)

Wen-Xuan Dai; Yuan-Ting Zhang; Jing Liu; Xiao-Rong Ding; Ni Zhao

2016-08-01

Accurate and ambulatory measurement of blood pressure (BP) is essential for efficient diagnosis, management and prevention of cardiovascular diseases (CVDs). However, traditional cuff-based BP measurement methods provide only intermittent BP readings and can cause discomfort with the occlusive cuff. Although pulse transit time (PTT) method is promising for cuffless and continuous BP measurement, its pervasive use is restricted by its limited accuracy and requirement of placing sensors on multiple body sites. To tackle these issues, we propose a novel dual-modality arterial pulse monitoring system for continuous blood pressure measurement, which simultaneously records the pressure and photoplethysmography (PPG) signals of radial artery. The obtained signals can be used to generate a pressure-volume curve, from which the elasticity index (EI) and viscosity index (VI) can be extracted. Experiments were carried out among 7 healthy subjects with their PPG, ECG, arterial pressure wave and reference BP collected to examine the effectiveness of the proposed indexes. The results of this study demonstrate that a linear regression model combining EI and VI has significantly higher BP tracking correlation coefficient as compared to the PTT method. This suggests that the proposed system and method can potentially be used for convenient and continuous blood pressure estimation with higher accuracy.

INTERACTION OF RADIATION WITH MATTER. LASER PLASMA: Increase in the amplitude of hf currents during exposure of a neutral target to microsecond CO2 laser pulses

Science.gov (United States)

Antipov, A. A.; Losev, Leonid L.; Meshalkin, E. A.

1988-09-01

High-frequency electric currents were generated by irradiation of a metal target with CO2 laser pulses. It was found that the region where the ambient gas was photoionized had a decisive influence on the hf current amplitude. A method for increasing the amplitude of the current by creating an auxiliary laser jet on the target was proposed and used. An hf current of up to 1 A amplitude was observed at a frequency of 75 MHz and this current lasted for 1.5 μs.

Pulse-periodic generation of supershort avalanche electron beams and X-ray emission

Science.gov (United States)

Baksht, E. Kh.; Burachenko, A. G.; Erofeev, M. V.; Tarasenko, V. F.

2014-05-01

Pulse-periodic generation of supershort avalanche electron beams (SAEBs) and X-ray emission in nitrogen, as well as the transition from a single-pulse mode to a pulse-periodic mode with a high repetition frequency, was studied experimentally. It is shown that, in the pulse-periodic mode, the full width at halfmaximum of the SAEB is larger and the decrease rate of the gap voltage is lower than those in the single-pulse mode. It is found that, when the front duration of the voltage pulse at a nitrogen pressure of 90 Torr decreases from 2.5 to 0.3 ns, the X-ray exposure dose in the pulse-periodic mode increases by more than one order of magnitude and the number of SAEB electrons also increases. It is shown that, in the pulse-periodic mode of a diffuse discharge, gas heating in the discharge gap results in a severalfold increase in the SAEB amplitude (the number of electrons in the beam). At a generator voltage of 25 kV, nitrogen pressure of 90 Torr, and pulse repetition frequency of 3.5 kHz, a runaway electron beam was detected behind the anode foil.

Numerical Analysis of Through Transmission Pulsed Eddy Current Testing and Effects of Pulse Width Variation

International Nuclear Information System (INIS)

Shin, Young Kil; Choi, Dong Myung

2007-01-01

By using numerical analysis methods, through transmission type pulsed eddy current (PEC) testing is modeled and PEC signal responses due to varying material conductivity, permeability, thickness, lift-off and pulse width are investigated. Results show that the peak amplitude of PEC signal gets reduced and the time to reach the peak amplitude is increased as the material conductivity, permeability, and specimen thickness increase. Also, they indicate that the pulse width needs to be shorter when evaluating the material conductivity and the plate thickness using the peak amplitude, and when the pulse width is long, the peak time is found to be more useful. Other results related to lift-off variation are reported as well

Acute changes in pulse pressure in relation to constituents of particulate air pollution in elderly persons

Energy Technology Data Exchange (ETDEWEB)

Jacobs, Lotte [Occupational and Environmental Medicine, Unit of Lung Toxicology, K.U.Leuven, Leuven (Belgium); Buczynska, Anna [Departement of Chemistry, UA, Wilrijk (Belgium); Walgraeve, Christophe [Research group EnVOC, Department of Sustainable Organic Chemistry and Technology, UGent, Gent (Belgium); Delcloo, Andy [Royal Meteorological Institute, Brussels (Belgium); Potgieter-Vermaak, Sanja [Departement of Chemistry, UA, Wilrijk (Belgium); Molecular Science Institute, School of Chemistry, University of Witwatersrand, Johannesburg (South Africa); Division of Chemistry and Environmental Science, Manchester Metropolitan University, Manchester (United Kingdom); Van Grieken, Rene [Departement of Chemistry, UA, Wilrijk (Belgium); Demeestere, Kristof; Dewulf, Jo; Van Langenhove, Herman [Research group EnVOC, Department of Sustainable Organic Chemistry and Technology, UGent, Gent (Belgium); De Backer, Hugo [Royal Meteorological Institute, Brussels (Belgium); Nemery, Benoit, E-mail: ben.nemery@med.kuleuven.be [Occupational and Environmental Medicine, Unit of Lung Toxicology, K.U.Leuven, Leuven (Belgium); Nawrot, Tim S. [Occupational and Environmental Medicine, Unit of Lung Toxicology, K.U.Leuven, Leuven (Belgium); Centre for Environmental Sciences, Hasselt University, Diepenbeek (Belgium)

2012-08-15

An increased pulse pressure (difference between systolic and diastolic blood pressure) suggests aortic stiffening. The objective of this study was to examine the acute effects of both particulate matter (PM) mass and composition on blood pressure, among elderly persons. We carried out a panel study in persons living in elderly homes in Antwerp, Belgium. We recruited 88 non-smoking persons, 70% women with a mean age of 83 years (standard deviation: 5.2). Blood pressure was measured and a blood sample was collected on two time points, which were chosen so that there was an exposure contrast in ambient PM exposure. The elemental content of the collected indoor and outdoor PM{sub 2.5} (particulate matter with an aerodynamic diameter <2.5 {mu}m) mass concentration was measured. Oxygenated polycyclic aromatic hydrocarbons (oxy-PAHs) on outdoor PM{sub 10} (particulate matter with an aerodynamic diameter <10 {mu}m) were measured. Each interquartile range increase of 20.8 {mu}g/m Superscript-Three in 24-h mean outdoor PM{sub 2.5} was associated with an increase in pulse pressure of 4.0 mmHg (95% confidence interval: 1.8-6.2), in persons taking antihypertensive medication (n=57), but not in persons not using antihypertensive medication (n=31) (p for interaction: 0.02). Vanadium, iron and nickel contents of PM{sub 2.5} were significantly associated with systolic blood pressure and pulse pressure, among persons on antihypertensive medication. Similar results were found for indoor concentrations. Of the oxy-PAHs, chrysene-5,6-dione and benzo[a]pyrene-3,6-dione were significantly associated with increases in systolic blood pressure and pulse pressure. In elderly, pulse pressure was positively associated with acute increases in outdoor and indoor air pollution, among persons taking antihypertensive medication. These results might form a mechanistic pathway linking air pollution as a trigger of cardiovascular events.

Ventricular repolarization time, location of pacing stimulus and current pulse amplitude conspire to determine arrhythmogenicity in mice

DEFF Research Database (Denmark)

Speerschneider, T; Grubb, Søren Jahn; Olesen, S P

2017-01-01

) were measured in isolated hearts using floating microelectrodes. RESULTS: Proarrhythmia in WT and KChIP2(-/-) was not sensitive to changes in refractory periods. Action potentials were longer in KChIP2(-/-) hearts compared to WT hearts. Isolated WT hearts had large apico-basal dispersion...... of repolarization time, whereas hearts from KChIP2(-/-) mice had large left-to-right ventricular dispersion of repolarization time. Pacing from the right ventricle in KChIP2(-/-) mice in vivo revealed significant lower current pulse amplitudes needed to induce arrhythmias in these mice. CONCLUSION: Large...

The association between brain-derived neurotrophic factor and central pulse pressure after an oral glucose tolerance test.

Science.gov (United States)

Lee, I-Te; Chen, Chen-Huan; Wang, Jun-Sing; Fu, Chia-Po; Lee, Wen-Jane; Liang, Kae-Woei; Lin, Shih-Yi; Sheu, Wayne Huey-Herng

2018-01-01

Arterial stiffening blunts postprandial vasodilatation. We hypothesized that brain-derived neurotrophic factor (BDNF) may modulate postprandial central pulse pressure, a surrogate marker for arterial stiffening. A total of 82 non-diabetic subjects received a 75-g oral glucose tolerance test (OGTT) after overnight fasting. Serum BDNF concentrations were determined at 0, 30, and 120min to calculate the area under the curve (AUC). Brachial and central blood pressures were measured using a noninvasive central blood pressure monitor before blood withdrawals at 0 and 120min. With the median AUC of BDNF of 45(ng/ml)∗h as the cutoff value, the central pulse pressure after glucose intake was significantly higher in the subjects with a low BDNF than in those with a high BDNF (63±16 vs. 53±11mmHg, P=0.003), while the brachial pulse pressure was not significantly different between the 2 groups (P=0.099). In a multivariate linear regression model, a lower AUC of BDNF was an independent predictor of a higher central pulse pressure after oral glucose intake (linear regression coefficient-0.202, 95% confidence interval-0.340 to -0.065, P=0.004). After oral glucose challenge, a lower serum BDNF response is significantly associated with a higher central pulse pressure. Copyright © 2017 Elsevier B.V. All rights reserved.

Observation of large-amplitude ion acoustic solitary waves in a plasma

International Nuclear Information System (INIS)

Nakamura, Yoshiharu

1987-01-01

Propagation of nonlinear ion acoustic waves in a multi-component plasma with negative ions is investigated in a double-plasma device. When the density of negative ions is larger than a critical value, a broad negative pulse evolves to rarefactive solitons, and a positive pulse whose amplitude is less than a certain threshold value becomes a subsonic wave train. In the same plasma, a positive pulse whose amplitude is larger than the threshold develops into a solitary wave. The critical amplitude is measured as a function of the density of negative ions and compared with predictions of the pseudo-potential method. The energy distribution of electrons in the solitary wave is also measured. (author)

Long-pulse hybrid scenario development in JT-60U

International Nuclear Information System (INIS)

Oyama, N.; Isayama, A.; Matsunaga, G.; Suzuki, T.; Takenaga, H.; Sakamoto, Y.; Nakano, T.; Kamada, Y.; Ide, S.

2009-01-01

The performance and sustained duration of long-pulse discharges for the 'ITER hybrid scenario' have been improved in JT-60U. The modification of power supply systems for three perpendicular neutral beam (NB) injections provides a long period of central NB heating up to 30 s, which is important for keeping the internal transport barrier (ITB). The peaked density profile in the core plasma can be maintained even when the density at the pedestal increased in the latter phase of the discharge due to the increase in the divertor recycling. Then, the peaked pressure profile attributed to the ITB can be kept constant through the discharge with the peaked power deposition profile. In these long-pulse discharges, MHD activity with toroidal mode number n = 1 is observed even when neoclassical tearing modes (NTMs) are suppressed. When the amplitude of the mode in the peripheral region becomes large, the pedestal pressure is degraded. The mode amplitude is sensitive to the toroidal magnetic field (or edge safety factor) and heating power. After the adjustment of the toroidal magnetic field so as to reduce the mode amplitude, a high normalized beta (β N ) of 2.6 and a high thermal confinement enhancement factor (H H98(y,2) > 1) are sustained for 25 s (∼14τ R , where τ R is the current diffusion time) under the ITER relevant small toroidal rotation condition. The peaked pressure profile in low safety factor plasma (safety factor at 95% flux surface q 95 ∼ 3.2) is stable against NTMs up to β N ∼ 3. A high β N H H98(y,2) of 2.6 gives a high G-factor ( β N H H98(y,2) /q 95 2 ) of 0.25 and a peaked pressure profile gives a large bootstrap current fraction (f BS > 0.43).

Pressure-Application Device for Testing Pressure Sensors

Science.gov (United States)

2002-01-01

A portable pressure-application device has been designed and built for use in testing and calibrating piezoelectric pressure transducers in the field. The device generates pressure pulses of known amplitude. A pressure pulse (in contradistinction to a steady pressure) is needed because in the presence of a steady pressure, the electrical output of a piezoelectric pressure transducer decays rapidly with time. The device includes a stainless- steel compressed-air-storage cylinder of 500 cu cm volume. A manual hand pump with check valves and a pressure gauge are located at one end of the cylinder. A three-way solenoid valve that controls the release of pressurized air is located at the other end of the cylinder. Power for the device is provided by a 3.7-V cordless-telephone battery. The valve is controlled by means of a pushbutton switch, which activates a 5 V to +/-15 V DC-to-DC converter that powers the solenoid. The outlet of the solenoid valve is connected to the pressure transducer to be tested. Before the solenoid is energized, the transducer to be tested is at atmospheric pressure. When the solenoid is actuated by the push button, pressurized air from inside the cylinder is applied to the transducer. Once the pushbutton is released, the cylinder pressure is removed from the transducer and the pressurized air applied to the transducer is vented, bringing the transducer back to atmospheric pressure. Before this device was used for actual calibration, its accuracy was checked with a NIST (National Institute of Standards and Technology) traceable calibrator and commercially calibrated pressure transducers. This work was done by Wanda Solano of Stennis Space Center and Greg Richardson of Lockheed Martin Corp.

Optical spectral reshaping for directly modulated 4-pulse amplitude modulation signals

DEFF Research Database (Denmark)

Ozolins, Oskars; Da Ros, Francesco; Cristofori, Valentina

2017-01-01

The tremendous traffic growth in intra/inter-datacenters requires low-cost high-speed integrated solutions [1]. To enable a significantly reduced footprint directly modulated lasers (DMLs) have been proposed instead of large external modulators. However, it is challenging to use DMLs due to their......The tremendous traffic growth in intra/inter-datacenters requires low-cost high-speed integrated solutions [1]. To enable a significantly reduced footprint directly modulated lasers (DMLs) have been proposed instead of large external modulators. However, it is challenging to use DMLs due...... (PAM) [3] signals. However, moving to 4-PAM,many of the impressive demonstrations reported so far rely heavily on off-line digital signal processing (DSP), which increases latency, power consumption and cost. In this talk, we report on (i) a detailed numerical analysis on the complex transfer function...... of the optical filter for optical spectral reshaping in case of pulse amplitude modulation and(ii) an experimental demonstration of real-time dispersion-uncompensated transmission of 10-GBd and 14-GBd 4-PAM signals up to 10- and 26-km SSMF. This is achieved by combining a commercial 10-Gb/s DML with optical...

Pulse-width discriminators

International Nuclear Information System (INIS)

Budyashov, Yu.G.; Grebenyuk, V.M.; Zinov, V.G.

1978-01-01

A pulse duration discriminator is described which is intended for processing signals from multilayer scintillators. The basic elements of the scintillator are: an input gate, a current generator, an integrating capacitor, a Schmidt trigger and an anticoincidence circuit. The basic circuit of the discriminator and its time diagrams explaining its operating are given. The discriminator is based on microcircuits. Pulse duration discrimination threshold changes continuously from 20 to 100 ns, while its amplitude threshold changes within 20 to 100 mV. The temperature instability of discrimination thresholds (both in pulse width and in amplitude) is better than 0.1 per cent/deg C

Perceived social isolation moderates the relationship between early childhood trauma and pulse pressure in older adults.

Science.gov (United States)

Norman, Greg J; Hawkley, Louise; Ball, Aaron; Berntson, Gary G; Cacioppo, John T

2013-06-01

Over a million children are subjected to some form of trauma in the United States every year. Early trauma has been shown to have deleterious effects on cardiovascular health in adulthood. However, the presence of strong social relationships as an adult can buffer an individual against many of the harmful effects of early trauma. Furthermore, the perception of social isolation has been shown to be a significant risk factor for the development of cardiovascular disease and is a strong predictor of all cause mortality. One likely mechanism thought to underlie the influence of perceived isolation on health is changes in arterial stiffness. One of the more widely used measures of arterial stiffness in older individuals is pulse pressure. The goal of the present study was to determine whether early childhood trauma is associated with elevations on pulse pressure. Furthermore, this study sought to determine whether perceived social isolation moderates the relationship between early trauma and pulse pressure. Results revealed that individuals with low perceived social isolation displayed no significant relationship between early trauma and pulse pressure. However, individuals who reported higher levels of perceived isolation showed a significant positive association between early trauma and pulse pressure. Therefore, the detrimental effects of early trauma may be partially dependent upon the quality of social relationships as an adult. Copyright © 2012 Elsevier B.V. All rights reserved.

All-fibre source of amplitude squeezed light pulses

Energy Technology Data Exchange (ETDEWEB)

Meissner, Markus; Marquardt, Christoph; Heersink, Joel; Gaber, Tobias; Wietfeld, Andre; Leuchs, Gerd; Andersen, Ulrik L [Institut fuer Optik, Information und Photonik, Max-Planck Forschungsgruppe Universitaet Erlangen-Nuernberg, Staudtstrasse 7/B2, 91058, Erlangen (Germany)

2004-08-01

An all-fibre source of amplitude squeezed solitons utilizing the self-phase modulation in an asymmetric Sagnac interferometer is experimentally demonstrated. The asymmetry of the interferometer is passively controlled by an integrated fibre coupler, allowing for the optimization of the noise reduction. We have carefully studied the dependence of the amplitude noise on the asymmetry and the power launched into the Sagnac interferometer. Qualitatively, we find good agreement between the experimental results, a semi-classical theory and earlier numerical calculations (Schmitt et al 1998 Phys. Rev. Lett. 81 2446). The stability and flexibility of this all-fibre source makes it particularly well suited to applications in quantum information science.

Characterization of pulsed atmospheric-pressure plasma streams (PAPS) generated by a plasma gun

Science.gov (United States)

Robert, E.; Sarron, V.; Riès, D.; Dozias, S.; Vandamme, M.; Pouvesle, J.-M.

2012-06-01

An experimental study of atmospheric-pressure rare gas plasma propagation in a high-aspect-ratio capillary is reported. The plasma is generated with a plasma gun device based on a dielectric barrier discharge (DBD) reactor powered by either nanosecond or microsecond rise-time high-voltage pulses at single-shot to multi-kHz frequencies. The influence of the voltage waveform, pulse polarity, pulse repetition rate and capillary material have been studied using nanosecond intensified charge-coupled device imaging and plasma-front velocity measurements. The evolution of the plasma appearance during its propagation and the study of the role of the different experimental parameters lead us to suggest a new denomination of pulsed atmospheric-pressure plasma streams to describe all the plasma features, including the previously so-called plasma bullet. The unique properties of such non-thermal plasma launching in capillaries, far from the primary DBD plasma, are associated with a fast ionization wave travelling with velocity in the 107-108 cm s-1 range. Voltage pulse tailoring is shown to allow for a significant improvement of such plasma delivery. Thus, the plasma gun device affords unique opportunities in biomedical endoscopic applications.

Characterization of pulsed atmospheric-pressure plasma streams (PAPS) generated by a plasma gun

International Nuclear Information System (INIS)

Robert, E; Sarron, V; Riès, D; Dozias, S; Vandamme, M; Pouvesle, J-M

2012-01-01

An experimental study of atmospheric-pressure rare gas plasma propagation in a high-aspect-ratio capillary is reported. The plasma is generated with a plasma gun device based on a dielectric barrier discharge (DBD) reactor powered by either nanosecond or microsecond rise-time high-voltage pulses at single-shot to multi-kHz frequencies. The influence of the voltage waveform, pulse polarity, pulse repetition rate and capillary material have been studied using nanosecond intensified charge-coupled device imaging and plasma-front velocity measurements. The evolution of the plasma appearance during its propagation and the study of the role of the different experimental parameters lead us to suggest a new denomination of pulsed atmospheric-pressure plasma streams to describe all the plasma features, including the previously so-called plasma bullet. The unique properties of such non-thermal plasma launching in capillaries, far from the primary DBD plasma, are associated with a fast ionization wave travelling with velocity in the 10 7 –10 8 cm s −1 range. Voltage pulse tailoring is shown to allow for a significant improvement of such plasma delivery. Thus, the plasma gun device affords unique opportunities in biomedical endoscopic applications. (paper)

Problems in nonlinear acoustics: Scattering of sound by sound, parametric receiving arrays, nonlinear effects in asymmetric sound beams and pulsed finite amplitude sound beams

Science.gov (United States)

Hamilton, Mark F.

1989-08-01

Four projects are discussed in this annual summary report, all of which involve basic research in nonlinear acoustics: Scattering of Sound by Sound, a theoretical study of two nonconlinear Gaussian beams which interact to produce sum and difference frequency sound; Parametric Receiving Arrays, a theoretical study of parametric reception in a reverberant environment; Nonlinear Effects in Asymmetric Sound Beams, a numerical study of two dimensional finite amplitude sound fields; and Pulsed Finite Amplitude Sound Beams, a numerical time domain solution of the KZK equation.

Association between pain episodes and high amplitude propagated pressure waves in patients with irritable bowel syndrome

NARCIS (Netherlands)

Clemens, C. H. M.; Samsom, M.; Roelofs, J. M. M.; van Berge Henegouwen, G. P.; Smout, A. J. P. M.

2003-01-01

OBJECTIVES: In the pathogenesis of irritable bowel syndrome (IBS), both increased visceral sensitivity and altered colonic motility seem to play a role. The aim of this study was to quantify the temporal relationship between pain episodes and the occurrence of high amplitude propagated pressure

Comparison of Ocular Pulse Amplitude Lowering Effects of Preservative-Free Tafluprost and Preservative-Free Dorzolamide-Timolol Fixed Combination Eyedrops.

Science.gov (United States)

Seo, Du Ri; Ha, Seung Joo

2015-01-01

To compare the ocular pulse amplitude (OPA) lowering effects of preservative-free tafluprost and dorzolamide-timolol fixed combination (DTFC) using dynamic contour tonometry. In total, 66 eyes of 66 patients with normal tension glaucoma (NTG) (n = 34) or primary open angle glaucoma (POAG) (n = 32) were included. Patients were divided into two groups: the preservative-free tafluprost-treated group (n = 33) and the preservative-free DTFC-treated group (n = 33). Intraocular pressure (IOP) was measured using Goldmann applanation tonometry (GAT). OPA was measured using dynamic contour tonometry; corrected OPA (cOPA) was calculated at baseline and at 1 week and 1, 3, and 6 months after treatment. After 6 months of treatment, tafluprost significantly reduced IOP (P < 0.001). The OPA lowering effects differed significantly between the two treatment groups (P = 0.003). The cOPA-lowering effect of tafluprost (1.09 mmHg) was significantly greater than that of DTFC (0.36 mmHg) after 6 months of treatment (P = 0.01). Tafluprost and DTFC glaucoma treatments provided marked OPA and IOP lowering effects. Tafluprost had a greater effect than DTFC; thus, this drug is recommended for patients at risk of glaucoma progression, due to the high OPA caused by large fluctuations in IOP.

The energy and temporal characteristics of orthogonal polarized waves generated by a transversely-excited pulsed CO/sub 2/ laser

Energy Technology Data Exchange (ETDEWEB)

Bertel, I.M.; Churakov, V.V.; Petukhov, V.O.; Prokopov, A.P.; Trushin, S.A.; Voitovich, A.P.

1980-01-01

The competition of orthogonally-polarized waves with various differences in the wave Q-factors and active medium pressures is studied. The possibility of controlling the parameters of a pulsed CO/sub 2/ laser by changing the value of the amplitude anisotropy of the cavity is demonstrated. The duration of the emission pulse for one of two orthogonal polarizations was reduced by virtually 50%.

Modelling of pulsed RF corona discharges in high-pressure air

International Nuclear Information System (INIS)

Auzas, F; Makarov, M; Naidis, G V

2012-01-01

An approach to description of pulsed RF corona discharges in high-pressure air is developed, based on the model of a filamentary discharge sustained by an electromagnetic wave guided along the plasma filament. Results of numerical simulation of spatial-temporal discharge dynamics at the quasi-stationary stage are obtained for various values of gas pressure and wave frequency. Experimental data on the discharge length versus the power absorbed by the discharge are presented. Their comparison with simulation results is given. (paper)

Changes in Cerebral Partial Oxygen Pressure and Cerebrovascular Reactivity During Intracranial Pressure Plateau Waves.

Science.gov (United States)

Lang, Erhard W; Kasprowicz, Magdalena; Smielewski, Peter; Pickard, John; Czosnyka, Marek

2015-08-01

Plateau waves in intracranial pressure (ICP) are frequently recorded in neuro intensive care and are not yet fully understood. To further investigate this phenomenon, we analyzed partial pressure of cerebral oxygen (pbtO2) and a moving correlation coefficient between ICP and mean arterial blood pressure (ABP), called PRx, along with the cerebral oxygen reactivity index (ORx), which is a moving correlation coefficient between cerebral perfusion pressure (CPP) and pbtO2 in an observational study. We analyzed 55 plateau waves in 20 patients after severe traumatic brain injury. We calculated ABP, ABP pulse amplitude (ampABP), ICP, CPP, pbtO2, heart rate (HR), ICP pulse amplitude (ampICP), PRx, and ORx, before, during, and after each plateau wave. The analysis of variance with Bonferroni post hoc test was used to compare the differences in the variables before, during, and after the plateau wave. We considered all plateau waves, even in the same patient, independent because they are separated by long intervals. We found increases for ICP and ampICP according to our operational definitions for plateau waves. PRx increased significantly (p = 0.00026), CPP (p pressure remains stable in ICP plateau waves, while cerebral autoregulatory indices show distinct changes, which indicate cerebrovascular reactivity impairment at the top of the wave. PbtO2 decreases during the waves and may show a slight overshoot after normalization. We assume that this might be due to different latencies of the cerebral blood flow and oxygen level control mechanisms. Other factors may include baseline conditions, such as pre-plateau wave cerebrovascular reactivity or pbtO2 levels, which differ between studies.

Corrections to the large-angle scattering amplitude

International Nuclear Information System (INIS)

Goloskokov, S.V.; Kudinov, A.V.; Kuleshov, S.P.

1979-01-01

High-energy behaviour of scattering amplitudes is considered within the frames of Logunov-Tavchelidze quasipotential approach. The representation of scattering amplitude of two scalar particles, convenient for the study of its asymptotic properties is given. Obtained are corrections of the main value of scattering amplitude of the first and the second orders in 1/p, where p is the pulse of colliding particles in the system of the inertia centre. An example of the obtained formulas use for a concrete quasipotential is given

Pulse Oximeter Derived Blood Pressure Measurement in Patients With a Continuous Flow Left Ventricular Assist Device.

Science.gov (United States)

Hellman, Yaron; Malik, Adnan S; Lane, Kathleen A; Shen, Changyu; Wang, I-Wen; Wozniak, Thomas C; Hashmi, Zubair A; Munson, Sarah D; Pickrell, Jeanette; Caccamo, Marco A; Gradus-Pizlo, Irmina; Hadi, Azam

2017-05-01

Currently, blood pressure (BP) measurement is obtained noninvasively in patients with continuous flow left ventricular assist device (LVAD) by placing a Doppler probe over the brachial or radial artery with inflation and deflation of a manual BP cuff. We hypothesized that replacing the Doppler probe with a finger-based pulse oximeter can yield BP measurements similar to the Doppler derived mean arterial pressure (MAP). We conducted a prospective study consisting of patients with contemporary continuous flow LVADs. In a small pilot phase I inpatient study, we compared direct arterial line measurements with an automated blood pressure (ABP) cuff, Doppler and pulse oximeter derived MAP. Our main phase II study included LVAD outpatients with a comparison between Doppler, ABP, and pulse oximeter derived MAP. A total of five phase I and 36 phase II patients were recruited during February-June 2014. In phase I, the average MAP measured by pulse oximeter was closer to arterial line MAP rather than Doppler (P = 0.06) or ABP (P < 0.01). In phase II, pulse oximeter MAP (96.6 mm Hg) was significantly closer to Doppler MAP (96.5 mm Hg) when compared to ABP (82.1 mm Hg) (P = 0.0001). Pulse oximeter derived blood pressure measurement may be as reliable as Doppler in patients with continuous flow LVADs. © 2016 International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.

Experimental hydrocephalus following mechanical increment of intraventricular pulse pressure.

Science.gov (United States)

Di Rocco, C; Pettorossi, V E; Caldarelli, M; Mancinelli, R; Velardi, F

1977-11-15

Experimental hydrocephalus has been induced in lambs by artificial increase of the amplitude of intraventricular cerebrospinal fluid (CSF) oscillations related to arterial pulsations, without concomitant changes of the mean CSF-pressure. The characteristics of this hydrocephalus demonstrate that the intraventricular CSF-pulsations can play a role in the genesis of ventricular dilation. Such a method may be used to produce an original model of hydrocephalus independent of changes of CSF-circulation or absorption.

Time-resolved investigation of an asymmetric bipolar pulsed magnetron deposition discharge: Influence of pressure

NARCIS (Netherlands)

Dunger, Th.; Welzel, Th.; Welzel, S.; Richter, F.

2005-01-01

A bipolar pulsed magnetron deposition discharge has been studied with pulse frequencies of 100 and 150 kHz, respectively. The discharge was operated in an argon/oxygen mixture at different total pressures with a circular magnesium target as cathode. Time-resolved Langmuir double probe measurements

Radar transponder operation with compensation for distortion due to amplitude modulation

Science.gov (United States)

Ormesher, Richard C [Albuquerque, NM; Tise, Bertice L [Albuquerque, NM; Axline, Jr., Robert M.

2011-01-04

In radar transponder operation, a variably delayed gating signal is used to gate a received radar pulse and thereby produce a corresponding gated radar pulse for transmission back to the source of the received radar pulse. This compensates for signal distortion due to amplitude modulation on the retransmitted pulse.

Ocular pressure waveform reflects ventricular bigeminy and aortic insufficiency

Directory of Open Access Journals (Sweden)

Jean B Kassem

2015-01-01

Full Text Available Ocular pulse amplitude (OPA is defined as the difference between maximum and minimum intraocular pressure (IOP during a cardiac cycle. Average values of OPA range from 1 to 4 mmHg. The purpose of this investigation is to determine the source of an irregular IOP waveform with elevated OPA in a 48-year-old male. Ocular pressure waveforms had an unusual shape consistent with early ventricular contraction. With a normal IOP, OPA was 9 mmHg, which is extraordinarily high. The subject was examined by a cardiologist and was determined to be in ventricular bigeminy. In addition, he had bounding carotid pulses and echocardiogram confirmed aortic insufficiency. After replacement of the aortic valve, the bigeminy resolved and the ocular pulse waveform became regular in appearance with an OPA of 1.6-2.0 mmHg. The ocular pressure waveform is a direct reflection of hemodynamics. Evaluating this waveform may provide an additional opportunity for screening subjects for cardiovascular anomalies and arrhythmias.

Statistical modelling of discharge behavior of atmospheric pressure dielectric barrier discharge

Energy Technology Data Exchange (ETDEWEB)

Tay, W. H.; Kausik, S. S.; Wong, C. S., E-mail: cswong@um.edu.my; Yap, S. L.; Muniandy, S. V. [Plasma Technology Research Centre, Department of Physics, Faculty of Science, University of Malaya, 50603 Kuala Lumpur (Malaysia)

2014-11-15

In this work, stochastic behavior of atmospheric pressure dielectric barrier discharge (DBD) has been investigated. The experiment is performed in a DBD reactor consisting of a pair of stainless steel parallel plate electrodes powered by a 50 Hz ac high voltage source. Current pulse amplitude distributions for different space gaps and the time separation between consecutive current pulses are studied. A probability distribution function is proposed to predict the experimental distribution function for the current pulse amplitudes and the occurrence of the transition regime of the pulse distribution. Breakdown voltage at different positions on the dielectric surface is suggested to be stochastic in nature. The simulated results based on the proposed distribution function agreed well with the experimental results and able to predict the regime of transition voltage. This model would be useful for the understanding of stochastic behaviors of DBD and the design of DBD device for effective operation and applications.

Pulse Shape Analysis and Discrimination for Silicon-Photomultipliers in Helium-4 Gas Scintillation Neutron Detector

Science.gov (United States)

Barker, Cathleen; Zhu, Ting; Rolison, Lucas; Kiff, Scott; Jordan, Kelly; Enqvist, Andreas

2018-01-01

Using natural helium (helium-4), the Arktis 180-bar pressurized gas scintillator is capable of detecting and distinguishing fast neutrons and gammas. The detector has a unique design of three optically separated segments in which 12 silicon-photomultiplier (SiPM) pairs are positioned equilaterally across the detector to allow for them to be fully immersed in the helium-4 gas volume; consequently, no additional optical interfaces are necessary. The SiPM signals were amplified, shaped, and readout by an analog board; a 250 MHz, 14-bit digitizer was used to examine the output pulses from each SiPMpair channel. The SiPM over-voltage had to be adjusted in order to reduce pulse clipping and negative overshoot, which was observed for events with high scintillation production. Pulse shaped discrimination (PSD) was conducted by evaluating three different parameters: time over threshold (TOT), pulse amplitude, and pulse integral. In order to differentiate high and low energy events, a 30ns gate window was implemented to group pulses from two SiPM channels or more for the calculation of TOT. It was demonstrated that pulses from a single SiPM channel within the 30ns window corresponded to low-energy gamma events while groups of pulses from two-channels or more were most likely neutron events. Due to gamma pulses having lower pulse amplitude, the percentage of measured gamma also depends on the threshold value in TOT calculations. Similarly, the threshold values were varied for the optimal PSD methods of using pulse amplitude and pulse area parameters. Helium-4 detectors equipped with SiPMs are excellent for in-the-field radiation measurement of nuclear spent fuel casks. With optimized PSD methods, the goal of developing a fuel cask content monitoring and inspection system based on these helium-4 detectors will be achieved.

Melodic algorithms for pulse oximetry to allow audible discrimination of abnormal systolic blood pressures.

Science.gov (United States)

Chima, Ranjit S; Ortega, Rafael; Connor, Christopher W

2014-12-01

An anesthesiologist must remain vigilant of the patient's clinical status, incorporating many independent physiological measurements. Oxygen saturation and heart rate are represented by continuous audible tones generated by the pulse oximeter, a mandated monitoring device. Other important clinical parameters--notably blood pressure--lack any audible representation beyond arbitrarily-configured threshold alarms. Attempts to introduce further continuous audible tones have apparently foundered; the complexity and interaction of these tones have exceeded the ability of clinicians to interpret them. Instead, we manipulate the tonal and rhythmic structure of the accepted pulse oximeter tone pattern melodically. Three melodic algorithms were developed to apply tonal and rhythmic variations to the continuous pulse oximeter tone, dependent on the systolic blood pressure. The algorithms distort the original audible pattern minimally, to facilitate comprehension of both the underlying pattern and the applied variations. A panel of anesthesia practitioners (attending anesthesiologists, residents and nurse anesthetists) assessed these algorithms in characterizing perturbations in cardiopulmonary status. Twelve scenarios, incorporating combinations of oxygen desaturation, bradycardia, tachycardia, hypotension and hypertension, were tested. A rhythmic variation in which additional auditory information was conveyed only at halftime intervals, with every other "beat" of the pulse oximeter, was strongly favored. The respondents also strongly favored the use of musical chords over single tones. Given three algorithms of tones embedded in the pulse oximeter signal, anesthesiologists preferred a melodic tone to signal a significant change in blood pressure.

A versatile programmable CAMAC random pulse generator

International Nuclear Information System (INIS)

Abdel-Aal, R.E.

1991-01-01

A new technique for generating linear pulses which can be random in both amplitude and time is described. With this technique, desired values for both pulse amplitude and spacing are set for the individual pulses by the software on a pulse-by-pulse basis. The versatility offered by this software programming allows a wide range of distributions to be obtained; with the user having close control on the distribution parameters. A number of such distributions may also be combined into a single output pulse stream. An implementation in a CAMAC module is presented. Both hardware and software aspects are described and typical performance results for amplitude and time distributions of the uniform and Gaussian type are given. Implications of using the pulser in a typical data acquisition environment on both the data acquisition and the pulser performance are considered. Typical applications are discussed together with some of the limitations. (orig.)

Supershort avalanche electron beams and x-ray in high-pressure nanosecond discharges

International Nuclear Information System (INIS)

Tarasenko, V F; Baksht, E H; Kostyrya, I D; Lomaev, M I; Rybka, D V

2008-01-01

The properties of a supershort avalanche electron beam (S AEB) and X-ray radiation produced using a nanosecond volume discharge are examined. An electron beam of the runaway electrons with amplitude of ∼ 50 A has been obtained in air atmospheric pressure. It is reported that S AEB is formed in the angle above 2π sr. Three groups of the runaway electrons are formed in a gas diode under atmospheric air pressure, when nanosecond voltage pulses with amplitude of hundreds of kilovolts are applied. The electron beam has been generated behind a 45 μm thick AlBe foil in SF 6 and Xe under the pressure of 2 arm, and in He under the pressure of about 12 atm. The paper gives the analysis of a generation mechanism of SAEB.

Stable radiation pressure acceleration of ions by suppressing transverse Rayleigh-Taylor instability with multiple Gaussian pulses

Energy Technology Data Exchange (ETDEWEB)

Zhou, M. L.; Liu, B.; Hu, R. H.; Shou, Y. R.; Lin, C.; Lu, H. Y.; Lu, Y. R.; Ma, W. J., E-mail: wenjun.ma@pku.edu.cn [State Key Laboratory of Nuclear Physics and Technology, and Key Laboratory of HEDP of the Ministry of Education, CAPT, Peking University, Beijing 100871 (China); Gu, Y. Q. [Laser Fusion Research Center, China Academy of Engineering Physics, Mianyang, Sichuan 621900 (China); Yan, X. Q., E-mail: x.yan@pku.edu.cn [State Key Laboratory of Nuclear Physics and Technology, and Key Laboratory of HEDP of the Ministry of Education, CAPT, Peking University, Beijing 100871 (China); Collaborative Innovation Center of Extreme Optics, Shanxi University, Taiyuan, Shanxi 030006 (China)

2016-08-15

In the case of a thin plasma slab accelerated by the radiation pressure of an ultra-intense laser pulse, the development of Rayleigh-Taylor instability (RTI) will destroy the acceleration structure and terminate the acceleration process much sooner than theoretical limit. In this paper, a new scheme using multiple Gaussian pulses for ion acceleration in a radiation pressure acceleration regime is investigated with particle-in-cell simulation. We found that with multiple Gaussian pulses, the instability could be efficiently suppressed and the divergence of the ion bunch is greatly reduced, resulting in a longer acceleration time and much more collimated ion bunch with higher energy than using a single Gaussian pulse. An analytical model is developed to describe the suppression of RTI at the laser-plasma interface. The model shows that the suppression of RTI is due to the introduction of the long wavelength mode RTI by the multiple Gaussian pulses.

Nasal continuous positive airway pressure: does bubbling improve gas exchange?

Science.gov (United States)

Morley, C J; Lau, R; De Paoli, A; Davis, P G

2005-07-01

In a randomised crossover trial, 26 babies, treated with Hudson prong continuous positive airway pressure (CPAP) from a bubbling bottle, received vigorous, high amplitude, or slow bubbling for 30 minutes. Pulse oximetry, transcutaneous carbon dioxide, and respiratory rate were recorded. The bubbling rates had no effect on carbon dioxide, oxygenation, or respiratory rate.

Explosive Processes on Cathode while Forming Nanosecond Pulsed Discharge of High Pressure

Directory of Open Access Journals (Sweden)

A. M. Hashimov

2012-01-01

Full Text Available The paper is devoted to research of cathode surfaces with different curvature radius (r = 1–8 mm while forming nanosecond pulsed discharge in dense air. Influence of field and air pressure heterogeneity rate in gas gap on size of micro-craters being formed on working cathode surface after pulsed effect has been shown in the paper. The paper reveals a maximum expansion of separate micro-crater size on cathode surface with small curvature radius.

Phase and amplitude control system for Stanford Linear Accelerator

International Nuclear Information System (INIS)

Yoo, S.J.

1983-01-01

The computer controlled phase and amplitude detection system measures the instantaneous phase and amplitude of a 1 micro-second 2856 MHz rf pulse at a 180 Hz rate. This will be used for phase feedback control, and also for phase and amplitude jitter measurement. The program, which was originally written by John Fox and Keith Jobe, has been modified to improve the function of the system. The software algorithms used in the measurement are described, as is the performance of the prototype phase and amplitude detector system

Influence of aerobic exercise training on post-exercise responses of aortic pulse pressure and augmentation pressure in postmenopausal women

Directory of Open Access Journals (Sweden)

Nobuhiko eAkazawa

2015-10-01

Full Text Available Central arterial blood pressure (BP is more predictive of future cardiovascular events than is brachial BP because it reflects the BP load imposed on the left ventricle with greater accuracy. However, little is known about the effects of exercise training on central hemodynamic response to acute exercise. The purpose of the present study was to determine the influence of an aerobic exercise regimen on the response of aortic BP after a single aerobic exercise in postmenopausal women. Nine healthy postmenopausal women (age: 61 ± 2 years participated in a 12-week aerobic exercise training regimen. Before and after the training, each subjects performed a single bout of cycling at ventilatory thresholds for 30 min. We evaluated the post-exercise aortic BP response, which was estimated via the general transfer function from applanation tonometry. After the initial pre-training aerobic exercise session, aortic BP did not change significantly: however, aortic pulse pressure and augmentation pressure were significantly attenuated after the single aerobic exercise session following the 12-week training regimen. The present study demonstrated that a regular aerobic exercise training regimen induced the post-exercise reduction of aortic pulse pressure and augmentation pressure. Regular aerobic exercise training may enhance post-exercise reduction in aortic BP.

An Ultra Low Noise Self-Starting Pulse Generator

DEFF Research Database (Denmark)

Lasri, J.; Bilenca, A.; Dahan, D.

2002-01-01

We describe a self-starting optical pulse source generating 10 GHz, 15 ps pulses with an average jitter of 43 fs and a o.15% amplitude noise over a frequency range of 500 Hz - 1 MHz.......We describe a self-starting optical pulse source generating 10 GHz, 15 ps pulses with an average jitter of 43 fs and a o.15% amplitude noise over a frequency range of 500 Hz - 1 MHz....

Individualized Low-Amplitude Seizure Therapy: Minimizing Current for Electroconvulsive Therapy and Magnetic Seizure Therapy

Science.gov (United States)

Peterchev, Angel V; Krystal, Andrew D; Rosa, Moacyr A; Lisanby, Sarah H

2015-01-01

Electroconvulsive therapy (ECT) at conventional current amplitudes (800–900 mA) is highly effective but carries the risk of cognitive side effects. Lowering and individualizing the current amplitude may reduce side effects by virtue of a less intense and more focal electric field exposure in the brain, but this aspect of ECT dosing is largely unexplored. Magnetic seizure therapy (MST) induces a weaker and more focal electric field than ECT; however, the pulse amplitude is not individualized and the minimum amplitude required to induce a seizure is unknown. We titrated the amplitude of long stimulus trains (500 pulses) as a means of determining the minimum current amplitude required to induce a seizure with ECT (bilateral, right unilateral, bifrontal, and frontomedial electrode placements) and MST (round coil on vertex) in nonhuman primates. Furthermore, we investigated a novel method of predicting this amplitude-titrated seizure threshold (ST) by a non-convulsive measurement of motor threshold (MT) using single pulses delivered through the ECT electrodes or MST coil. Average STs were substantially lower than conventional pulse amplitudes (112–174 mA for ECT and 37.4% of maximum device amplitude for MST). ST was more variable in ECT than in MST. MT explained 63% of the ST variance and is hence the strongest known predictor of ST. These results indicate that seizures can be induced with less intense electric fields than conventional ECT that may be safer; efficacy and side effects should be evaluated in clinical studies. MT measurement could be a faster and safer alternative to empirical ST titration for ECT and MST. PMID:25920013

Detection of small-amplitude periodic surface pressure fluctuation by pressure-sensitive paint measurements using frequency-domain methods

Science.gov (United States)

Noda, Takahiro; Nakakita, Kazuyki; Wakahara, Masaki; Kameda, Masaharu

2018-06-01

Image measurement using pressure-sensitive paint (PSP) is an effective tool for analyzing the unsteady pressure field on the surface of a body in a low-speed air flow, which is associated with wind noise. In this study, the surface pressure fluctuation due to the tonal trailing edge (TE) noise for a two-dimensional NACA 0012 airfoil was quantitatively detected using a porous anodized aluminum PSP (AA-PSP). The emission from the PSP upon illumination by a blue laser diode was captured using a 12-bit high-speed complementary metal-oxide-semiconductor (CMOS) camera. The intensities of the captured images were converted to pressures using a standard intensity-based method. Three image-processing methods based on the fast Fourier transform (FFT) were tested to determine their efficiency in improving the signal-to-noise ratio (SNR) of the unsteady PSP data. In addition to two fundamental FFT techniques (the full data and ensemble averaging FFTs), a technique using the coherent output power (COP), which involves the cross correlation between the PSP data and the signal measured using a pointwise sound-level meter, was tested. Preliminary tests indicated that random photon shot noise dominates the intensity fluctuations in the captured PSP emissions above 200 Hz. Pressure fluctuations associated with the TE noise, whose dominant frequency is approximately 940 Hz, were successfully measured by analyzing 40,960 sequential PSP images recorded at 10 kfps. Quantitative validation using the power spectrum indicates that the COP technique is the most effective method of identification of the pressure fluctuation directly related to TE noise. It is possible to distinguish power differences with a resolution of 10 Pa^2 (4 Pa in amplitude) when the COP was employed without use of another wind-off data. This resolution cannot be achieved by the ensemble averaging FFT because of an insufficient elimination of the background noise.

Current pulse generator of an induction accelerator electromagnet

International Nuclear Information System (INIS)

Baginskij, B.A.; Makarevich, V.N.; Shtejn, M.M.

1987-01-01

Thyristor generator forming in betatron electromagnet coil sinusoidal and quasisinusoidal current unipolar pulses, the field being deforced at the beginning of acceleration cycle, and with the pulse flat top in the cycle end, is described. The current amplitude is controlled by pulse-phase method. The current pulse time shift permitted to decrease the loss rate in the accumulating capacitor. The generator is used in systems with 1-10 ms pulse duration, electromagnet magnetic field maximal energy - 45-450 J, the voltage amplitude in the coil 960-1500 V and amplitude of the current passing the coil 100-500 A, the repetition frequency being 50-200 Hz. In particular, the generator is used to supply betatrons designed for defectoscopy in nonstationary conditions, the accelerated electron energy being 4, 6, 8 and 15 MeV

Acoustic pressure waves induced in human heads by RF pulses from high-field MRI scanners.

Science.gov (United States)

Lin, James C; Wang, Zhangwei

2010-04-01

The current evolution toward greater image resolution from magnetic resonance image (MRI) scanners has prompted the exploration of higher strength magnetic fields and use of higher levels of radio frequencies (RFs). Auditory perception of RF pulses by humans has been reported during MRI with head coils. It has shown that the mechanism of interaction for the auditory effect is caused by an RF pulse-induced thermoelastic pressure wave inside the head. We report a computational study of the intensity and frequency of thermoelastic pressure waves generated by RF pulses in the human head inside high-field MRI and clinical scanners. The U.S. Food and Drug Administration (U.S. FDA) guides limit the local specific absorption rate (SAR) in the body-including the head-to 8 W kg(-1). We present results as functions of SAR and show that for a given SAR the peak acoustic pressures generated in the anatomic head model were essentially the same at 64, 300, and 400 MHz (1.5, 7.0, and 9.4 T). Pressures generated in the anatomic head are comparable to the threshold pressure of 20 mPa for sound perception by humans at the cochlea for 4 W kg(-1). Moreover, results indicate that the peak acoustic pressure in the brain is only 2 to 3 times the auditory threshold at the U.S. FDA guideline of 8 W kg(-1). Even at a high SAR of 20 W kg(-1), where the acoustic pressure in the brain could be more than 7 times the auditory threshold, the sound pressure levels would not be more than 17 db above threshold of perception at the cochlea.

Pulse timing for cataclysmic variables

International Nuclear Information System (INIS)

Chester, T.J.

1979-01-01

It is shown that present pulse timing measurements of cataclysmic variables can be explained by models of accretion disks in these systems, and thus such measurements can constrain disk models. The model for DQ Her correctly predicts the amplitude variation of the continuum pulsation and can also perhaps explain the asymmetric amplitude of the pulsed lambda4686 emission line. Several other predictions can be made from the model. In particular, if pulse timing measurements that resolve emission lines both in wavelength and in binary phase can be made, the projected orbital radius of the white dwarf could be deduced

Subnanosecond breakdown development in high-voltage pulse discharge: Effect of secondary electron emission

Science.gov (United States)

Alexandrov, A. L.; Schweigert, I. V.; Zakrevskiy, Dm. E.; Bokhan, P. A.; Gugin, P.; Lavrukhin, M.

2017-10-01

A subnanosecond breakdown in high-voltage pulse discharge may be a key tool for superfast commutation of high power devices. The breakdown in high-voltage open discharge at mid-high pressure in helium was studied in experiment and in kinetic simulations. The kinetic model of electron avalanche development was constructed, based on PIC-MCC simulations, including dynamics of electrons, ions and fast helium atoms, produced by ions scattering. Special attention was paid to electron emission processes from cathode, such as: photoemission by Doppler-shifted resonant photons, produced in excitation processes involving fast atoms; electron emission by ions and fast atoms bombardment of cathode; the secondary electron emission (SEE) by hot electrons from bulk plasma. The simulations show that the fast atoms accumulation is the main reason of emission growth at the early stage of breakdown, but at the final stage, when the voltage on plasma gap diminishes, namely the SEE is responsible for subnanosecond rate of current growth. It was shown that the characteristic time of the current growth can be controlled by the SEE yield. The influence of SEE yield for three types of cathode material (titanium, SiC, and CuAlMg-alloy) was tested. By changing the pulse voltage amplitude and gas pressure, the area of existence of subnanosecond breakdown is identified. It is shown that in discharge with SiC and CuAlMg-alloy cathodes (which have enhanced SEE) the current can increase with a subnanosecond characteristic time value as small as τs = 0.4 ns, for the pulse voltage amplitude of 5÷12 kV. An increase of gas pressure from 15 Torr to 30 Torr essentially decreases the time of of current front growth, whereas the pulse voltage variation weakly affects the results.

Broadband homonuclear TOCSY with amplitude and phase-modulated RF mixing schemes

International Nuclear Information System (INIS)

Kirschstein, Anika; Herbst, Christian; Riedel, Kerstin; Carella, Michela; Leppert, Joerg; Ohlenschlaeger, Oliver; Goerlach, Matthias; Ramachandran, Ramadurai

2008-01-01

We have explored the design of broadband scalar coupling mediated 13 C- 13 C and cross-relaxation suppressed 1 H- 1 H TOCSY sequences employing phase/amplitude modulated inversion pulses. Considering a variety of supercycles, pulsewidths and a RF field strength of 10 kHz, the Fourier coefficients defining the amplitude and phase modulation profiles of the 180 deg. pulses were optimised numerically so as to obtain efficient magnetisation transfer within the desired range of resonance offsets. The coherence transfer characteristics of the mixing schemes were assessed via numerical simulations and experimental measurements and were compared with commonly used sequences based on rectangular RF pulses. The efficacies of the clean 1 H- 1 H TOCSY sequences were also examined via numerical simulations for application to weakly oriented systems and sequences with efficient, broadband and clean dipolar transfer characteristics were identified. In general, the amplitude and phase modulated TOCSY sequences presented here have moderately better performance characteristics than the sequences currently employed in biomolecular NMR spectroscopy

Determination of etching parameters for pulsed XeF2 etching of silicon using chamber pressure data

Science.gov (United States)

Sarkar, Dipta; Baboly, M. G.; Elahi, M. M.; Abbas, K.; Butner, J.; Piñon, D.; Ward, T. L.; Hieber, Tyler; Schuberth, Austin; Leseman, Z. C.

2018-04-01

A technique is presented for determination of the depletion of the etchant, etched depth, and instantaneous etch rate for Si etching with XeF2 in a pulsed etching system in real time. The only experimental data required is the pressure data collected temporally. Coupling the pressure data with the knowledge of the chemical reactions allows for the determination of the etching parameters of interest. Using this technique, it is revealed that pulsed etching processes are nonlinear, with the initial etch rate being the highest and monotonically decreasing as the etchant is depleted. With the pulsed etching system introduced in this paper, the highest instantaneous etch rate of silicon was recorded to be 19.5 µm min-1 for an initial pressure of 1.2 Torr for XeF2. Additionally, the same data is used to determine the rate constant for the reaction of XeF2 with Si; the reaction is determined to be second order in nature. The effect of varying the exposed surface area of Si as well as the effect that pressure has on the instantaneous etch rate as a function of time is shown applying the same technique. As a proof of concept, an AlN resonator is released using XeF2 pulses to remove a sacrificial poly-Si layer.

Blood pressure and pulse rate of apparently healthy adults on land ...

African Journals Online (AJOL)

Blood pressure and pulse rate of apparently healthy adults on land and in water: A comparative study. AI Bello, BOA Adegoke, OA Abass, O Addo. Abstract. Objective: The study compared cardiovascular parameters of apparently healthy adults in erect standing posture on land and whilst immersed in water at rest. Methods: ...

Plasma density enhancement in atmospheric-pressure dielectric-barrier discharges by high-voltage nanosecond pulse in the pulse-on period: a PIC simulation

International Nuclear Information System (INIS)

Sang Chaofeng; Sun Jizhong; Wang Dezhen

2010-01-01

A particle-in-cell (PIC) plus Monte Carlo collision simulation is employed to investigate how a sustainable atmospheric pressure single dielectric-barrier discharge responds to a high-voltage nanosecond pulse (HVNP) further applied to the metal electrode. The results show that the HVNP can significantly increase the plasma density in the pulse-on period. The ion-induced secondary electrons can give rise to avalanche ionization in the positive sheath, which widens the discharge region and enhances the plasma density drastically. However, the plasma density stops increasing as the applied pulse lasts over certain time; therefore, lengthening the pulse duration alone cannot improve the discharge efficiency further. Physical reasons for these phenomena are then discussed.

Plasma density enhancement in atmospheric-pressure dielectric-barrier discharges by high-voltage nanosecond pulse in the pulse-on period: a PIC simulation

Science.gov (United States)

Sang, Chaofeng; Sun, Jizhong; Wang, Dezhen

2010-02-01

A particle-in-cell (PIC) plus Monte Carlo collision simulation is employed to investigate how a sustainable atmospheric pressure single dielectric-barrier discharge responds to a high-voltage nanosecond pulse (HVNP) further applied to the metal electrode. The results show that the HVNP can significantly increase the plasma density in the pulse-on period. The ion-induced secondary electrons can give rise to avalanche ionization in the positive sheath, which widens the discharge region and enhances the plasma density drastically. However, the plasma density stops increasing as the applied pulse lasts over certain time; therefore, lengthening the pulse duration alone cannot improve the discharge efficiency further. Physical reasons for these phenomena are then discussed.

Pulsed Electron Source with Grid Plasma Cathode and Longitudinal Magnetic Field for Modification of Material and Product Surfaces

Science.gov (United States)

Devyatkov, V. N.; Koval, N. N.

2018-01-01

The description and the main characteristics of the pulsed electron source "SOLO" developed on the basis of the plasma cathode with grid stabilization of the emission plasma boundary are presented. The emission plasma is generated by a low-pressure arc discharge, and that allows to form the dense low-energy electron beam with a wide range of independently adjustable parameters of beam current pulses (pulse duration of 20-250 μs, pulse repetition rate of 1-10 s-1, amplitude of beam current pulses of 20-300 A, and energy of beam electrons of 5-25 keV). The special features of generation of emission plasma by constricted low-pressure arc discharge in the grid plasma cathode partially dipped into a non-uniform magnetic field and of formation and transportation of the electron beam in a longitudinal magnetic field are considered. The application area of the electron source and technologies realized with its help are specified.

Evaluation of dynamic range for LLNL streak cameras using high contrast pulsed and pulse podiatry on the Nova laser system

International Nuclear Information System (INIS)

Richards, J.B.; Weiland, T.L.; Prior, J.A.

1990-01-01

This paper reports on a standard LLNL streak camera that has been used to analyze high contrast pulses on the Nova laser facility. These pulses have a plateau at their leading edge (foot) with an amplitude which is approximately 1% of the maximum pulse height. Relying on other features of the pulses and on signal multiplexing, we were able to determine how accurately the foot amplitude was being represented by the camera. Results indicate that the useful single channel dynamic range of the instrument approaches 100:1

<3> OMEGA pulse-forming network

CERN Multimedia

1974-01-01

Adjustement of the 3 W pulse-forming network of the SPS beam dumping system. When charged at 60 kV, this PFN gives 10 kA, 25 ms current pulses, with oscillations, superimposed on the pulse flat top, of an amplitude of +/- 1 Ka.

Automatic algorithm for monitoring systolic pressure variation and difference in pulse pressure.

Science.gov (United States)

Pestel, Gunther; Fukui, Kimiko; Hartwich, Volker; Schumacher, Peter M; Vogt, Andreas; Hiltebrand, Luzius B; Kurz, Andrea; Fujita, Yoshihisa; Inderbitzin, Daniel; Leibundgut, Daniel

2009-06-01

Difference in pulse pressure (dPP) reliably predicts fluid responsiveness in patients. We have developed a respiratory variation (RV) monitoring device (RV monitor), which continuously records both airway pressure and arterial blood pressure (ABP). We compared the RV monitor measurements with manual dPP measurements. ABP and airway pressure (PAW) from 24 patients were recorded. Data were fed to the RV monitor to calculate dPP and systolic pressure variation in two different ways: (a) considering both ABP and PAW (RV algorithm) and (b) ABP only (RV(slim) algorithm). Additionally, ABP and PAW were recorded intraoperatively in 10-min intervals for later calculation of dPP by manual assessment. Interobserver variability was determined. Manual dPP assessments were used for comparison with automated measurements. To estimate the importance of the PAW signal, RV(slim) measurements were compared with RV measurements. For the 24 patients, 174 measurements (6-10 per patient) were recorded. Six observers assessed dPP manually in the first 8 patients (10-min interval, 53 measurements); no interobserver variability occurred using a computer-assisted method. Bland-Altman analysis showed acceptable bias and limits of agreement of the 2 automated methods compared with the manual method (RV: -0.33% +/- 8.72% and RV(slim): -1.74% +/- 7.97%). The difference between RV measurements and RV(slim) measurements is small (bias -1.05%, limits of agreement 5.67%). Measurements of the automated device are comparable with measurements obtained by human observers, who use a computer-assisted method. The importance of the PAW signal is questionable.

A new mathematical model of wrist pulse waveforms characterizes patients with cardiovascular disease - A pilot study.

Science.gov (United States)

He, Dianning; Wang, Lu; Fan, Xiaobing; Yao, Yang; Geng, Ning; Sun, Yingxian; Xu, Lisheng; Qian, Wei

2017-10-01

The purpose of this study was to analyze and compare a series of measured radial pulse waves as a function of contact pressure for young and old healthy volunteers, and old patients with cardiovascular disease. The radial pulse waves were detected with a pressure sensor and the contact pressure of the sensor was incremented by 20gf during the signal acquisition. A mathematical model of radial pulse waveform was developed by using two Gaussian functions modulated by radical functions and used to fit the pulse waveforms. Then, a ratio of area (r A ) and a ratio of peak height (r PH ) between percussion wave and dicrotic wave as a function of contact pressure were calculated based on fitted parameters. The results demonstrated that there was a maximum for waveform peak height, a minimum for r A (r A min ) and a minimum for r PH (r PH min ) appeared as contact pressure varied. On average, older patients had higher peak amplitude and a significantly smaller r A min (pmathematical model had moderate to strong positive linear correlations (r=0.66 to 0.84, pmodel. The receiver operating characteristic (ROC) analysis showed that the r A min calculated with the model and the contact pressure measured at the r A min had good diagnostic accuracy to distinguish healthy volunteers vs. diseased patients. Therefore, using the mathematical model to quantitatively analyze the radial pulse waveforms as a function of contact pressure could be useful in the diagnosis of cardiovascular diseases. Copyright © 2017 IPEM. Published by Elsevier Ltd. All rights reserved.

Pulse Combustor Driven Pressure Gain Combustion for High Efficiency Gas Turbine Engines

KAUST Repository

Lisanti, Joel

2017-02-01

The gas turbine engine is an essential component of the global energy infrastructure which accounts for a significant portion of the total fossil fuel consumption in transportation and electric power generation sectors. For this reason there is significant interest in further increasing the efficiency and reducing the pollutant emissions of these devices. Conventional approaches to this goal, which include increasing the compression ratio, turbine inlet temperature, and turbine/compressor efficiency, have brought modern gas turbine engines near the limits of what may be achieved with the conventionally applied Brayton cycle. If a significant future step increase in gas turbine efficiency is to be realized some deviation from this convention is necessary. The pressure gain gas turbine concept is a well established new combustion technology that promises to provide a dramatic increase in gas turbine efficiency by replacing the isobaric heat addition process found in conventional technology with an isochoric process. The thermodynamic benefit of even a small increase in stagnation pressure across a gas turbine combustor translates to a significant increase in cycle efficiency. To date there have been a variety of methods proposed for achieving stagnation pressure gains across a gas turbine combustor and these concepts have seen a broad spectrum of levels of success. The following chapter provides an introduction to one of the proposed pressure gain methods that may be most easily realized in a practical application. This approach, known as pulse combustor driven pressure gain combustion, utilizes an acoustically resonant pulse combustor to approximate isochoric heat release and thus produce a rise in stagnation pressure.

Repetitive transcranial magnetic stimulator with controllable pulse parameters

Science.gov (United States)

Peterchev, Angel V.; Murphy, David L.; Lisanby, Sarah H.

2011-06-01

The characteristics of transcranial magnetic stimulation (TMS) pulses influence the physiological effect of TMS. However, available TMS devices allow very limited adjustment of the pulse parameters. We describe a novel TMS device that uses a circuit topology incorporating two energy storage capacitors and two insulated-gate bipolar transistor (IGBT) modules to generate near-rectangular electric field pulses with adjustable number, polarity, duration, and amplitude of the pulse phases. This controllable pulse parameter TMS (cTMS) device can induce electric field pulses with phase widths of 10-310 µs and positive/negative phase amplitude ratio of 1-56. Compared to conventional monophasic and biphasic TMS, cTMS reduces energy dissipation up to 82% and 57% and decreases coil heating up to 33% and 41%, respectively. We demonstrate repetitive TMS trains of 3000 pulses at frequencies up to 50 Hz with electric field pulse amplitude and width variability less than the measurement resolution (1.7% and 1%, respectively). Offering flexible pulse parameter adjustment and reduced power consumption and coil heating, cTMS enhances existing TMS paradigms, enables novel research applications and could lead to clinical applications with potentially enhanced potency.

Programmable pulse generator

International Nuclear Information System (INIS)

Xue Zhihua; Lou Binqiao; Duan Xiaohui

2002-01-01

The author introduces the design of programmable pulse generator that is based on a micro-controller and controlled by RS232 interface of personal computer. The whole system has good stability. The pulse generator can produce TTL pulse and analog pulse. The pulse frequency can be selected by EPLD. The voltage amplitude and pulse width of analog pulse can be adjusted by analog switches and digitally-controlled potentiometers. The software development tools of computer is National Instruments LabView5.1. The front panel of this virtual instrumentation is intuitive and easy-to-use. Parameters can be selected and changed conveniently by knob and slide

Direct injection of high pressure gas : scaling properties of pulsed turbulent jets

NARCIS (Netherlands)

Baert, R.S.G.; Klaassen, A.; Doosje, E.

2010-01-01

Existing gasoline DI injection equipment has been modified to generate single hole pulsed gas jets. Injection experiments have been performed at combinations of 3 different pressure ratios (2 of which supercritical) respectively 3 different hole geometries (i.e. length to diameter ratios). Injection

REFLECTANCE PULSE OXIMETRY AT THE FOREHEAD IMPROVES BY PRESSURE ON THE PROBE

NARCIS (Netherlands)

DASSEL, ACM; GRAAFF, R; SIKKEMA, M; ZIJLSTRA, WG; AARNOUDSE, JG

In this study, we investigated the possibility of improving reflectance (back-scatter) pulse oximetry measurements by pressure applied to the probe. Optimal signal detection, with the probe applied to an easily accessible location, is important to prevent erroneous oxygen saturation readouts. At the

Finite-amplitude, pulsed, ultrasonic beams

Science.gov (United States)

Coulouvrat, François; Frøysa, Kjell-Eivind

An analytical, approximate solution of the inviscid KZK equation for a nonlinear pulsed sound beam radiated by an acoustic source with a Gaussian velocity distribution, is obtained by means of the renormalization method. This method involves two steps. First, the transient, weakly nonlinear field is computed. However, because of cumulative nonlinear effects, that expansion is non-uniform and breaks down at some distance away from the source. So, in order to extend its validity, it is re-written in a new frame of co-ordinates, better suited to following the nonlinear distorsion of the wave profile. Basically, the nonlinear coordinate transform introduces additional terms in the expansion, which are chosen so as to counterbalance the non-uniform ones. Special care is devoted to the treatment of shock waves. Finally, comparisons with the results of a finite-difference scheme turn out favorable, and show the efficiency of the method for a rather large range of parameters.

A hybrid pulse combining topology utilizing the combination of modularized avalanche transistor Marx circuits, direct pulse adding, and transmission line transformer.

Science.gov (United States)

Li, Jiangtao; Zhao, Zheng; Sun, Yi; Liu, Yuhao; Ren, Ziyuan; He, Jiaxin; Cao, Hui; Zheng, Minjun

2017-03-01

Numerous applications driven by pulsed voltage require pulses to be with high amplitude, high repetitive frequency, and narrow width, which could be satisfied by utilizing avalanche transistors. The output improvement is severely limited by power capacities of transistors. Pulse combining is an effective approach to increase the output amplitude while still adopting conventional pulse generating modules. However, there are drawbacks in traditional topologies including the saturation tendency of combining efficiency and waveform oscillation. In this paper, a hybrid pulse combining topology was adopted utilizing the combination of modularized avalanche transistor Marx circuits, direct pulse adding, and transmission line transformer. The factors affecting the combining efficiency were determined including the output time synchronization of Marx circuits, and the quantity and position of magnetic cores. The numbers of the parallel modules and the stages were determined by the output characteristics of each combining method. Experimental results illustrated the ability of generating pulses with 2-14 kV amplitude, 7-11 ns width, and a maximum 10 kHz repetitive rate on a matched 50-300 Ω resistive load. The hybrid topology would be a convinced pulse combining method for similar nanosecond pulse generators based on the solid-state switches.

Twenty-channel high-voltage pulse generators

International Nuclear Information System (INIS)

Anan'in, P.S.; Kashirin, A.P.

1980-01-01

A 20-channel high-voltage pulse generator operating with a mismatched load is described. The generator contains shaping lines 20 m long made of coaxial cable, a trigatron-type discharged, and isolating plates. The channel characteristic impedance is 50 Ohm. The maximum pulse amplitude is up to 15 kV on a high-resistance load and 7.5 kV on a matched one. The pulse duration is 100 ns at a pulse rise time of 12 ns, the delay introduced by the generator is 200 +-2.5 ns. Provision is made in the control circuit for compensation of the shaped pulse and separation of a pulse reflected from the load. The reflected pulse shape and amplitude characterize load parameters. Generator tests proved its high operational reliability (after 10 5 operations no significant changes in generator performances have been observed). The generator is intended for filmless data output from spark chambers

Some characteristics of the digitization pulses from high pressure neon-helium flash tubes

International Nuclear Information System (INIS)

Chan, D.S.K.; Leung, S.K.; Ng, L.K.

1979-01-01

Characteristics of the digitization output pulses from high pressure neon-helium flash tubes were studied under various operation conditions using square ultra-high voltage pulses. Properties reported by previous workers were compared. Two discharge mechanisms, the Townsend avalanche discharge and the streamer discharge, were observed to occur in sequence in some events. The output waveforms for both discharge mechanisms were studied in detail. The charge induced on a detecting probe was also estimated from the measured data. (Auth.)

Pulmonary artery pulse pressure and wave reflection in chronic pulmonary thromboembolism and primary pulmonary hypertension.

Science.gov (United States)

Castelain, V; Hervé, P; Lecarpentier, Y; Duroux, P; Simonneau, G; Chemla, D

2001-03-15

The purpose of this time-domain study was to compare pulmonary artery (PA) pulse pressure and wave reflection in chronic pulmonary thromboembolism (CPTE) and primary pulmonary hypertension (PPH). Pulmonary artery pressure waveform analysis provides a simple and accurate estimation of right ventricular afterload in the time-domain. Chronic pulmonary thromboembolism and PPH are both responsible for severe pulmonary hypertension. Chronic pulmonary thromboembolism and PPH predominantly involve proximal and distal arteries, respectively, and may lead to differences in PA pressure waveform. High-fidelity PA pressure was recorded in 14 patients (7 men/7 women, 46 +/- 14 years) with CPTE (n = 7) and PPH (n = 7). We measured thermodilution cardiac output, mean PA pressure (MPAP), PA pulse pressure (PAPP = systolic - diastolic PAP) and normalized PAPP (nPAPP = PPAP/MPAP). Wave reflection was quantified by measuring Ti, that is, the time between pressure upstroke and the systolic inflection point (Pi), deltaP, that is, the systolic PAP minus Pi difference, and the augmentation index (deltaP/PPAP). At baseline, CPTE and PPH had similar cardiac index (2.4 +/- 0.4 vs. 2.5 +/- 0.5 l/min/m2), mean PAP (59 +/- 9 vs. 59 +/- 10 mm Hg), PPAP (57 +/- 13 vs. 53 +/- 13 mm Hg) and nPPAP (0.97 +/- 0.16 vs. 0.89 +/- 0.13). Chronic pulmonary thromboembolism had shorter Ti (90 +/- 17 vs. 126 +/- 16 ms, p PPAP (0.26 +/- 0.01 vs. 0.09 +/- 0.07, p < 0.01). Our study indicated that: 1) CPTE and PPH with severe pulmonary hypertension had similar PA pulse pressure, and 2) wave reflection is elevated in both groups, and CPTE had increased and anticipated wave reflection as compared with PPH, thus suggesting differences in the pulsatile component of right ventricular afterload.

Energy and dose characteristics of ion bombardment during pulsed laser deposition of thin films under pulsed electric field

International Nuclear Information System (INIS)

Fominski, V.Yu.; Nevolin, V.N.; Smurov, I.

2004-01-01

Experiments on pulsed laser deposition of Fe films on Si substrates were performed with the aim to analyze the role of factors determining the formation of an energy spectrum and a dose of ions bombarding the film in strong pulsed electric fields. The amplitude of the high-voltage pulse (-40 kV) applied to the substrate and the laser fluence at the Fe target were fixed during the deposition. Owing to the high laser fluence (8 J/cm 2 ) at a relatively low power (20 mJ), the ionization of the laser plume was high, but the Fe vapor pressure near the substrate was low enough to avoid arcing. Electric signals from a target exposed to laser radiation were measured under different conditions (at different delay times) of application of electric pulses. The Si(100) substrates were analyzed using Rutherford ion backscattering/channeling spectrometry. The ion implantation dose occurred to be the highest if the high-voltage pulse was applied at a moment of time when the ion component of the plume approached the substrate. In this case, the implanted ions had the highest energy determined by the amplitude of the electric pulse. An advance or delay in applying a high-voltage pulse caused the ion dose and energy to decrease. A physical model incorporating three possible modes of ion implantation was proposed for the interpretation of the experimental results. If a laser plume was formed in the external field, ions were accelerated from the front of the dense plasma, and the ion current depended on the gas-dynamic expansion of the plume. The application of a high-voltage pulse, at the instant when the front approached the substrate, maintained the mode that was characteristic of the traditional plasma immersion ion implantation, and the ion current was governed by the dynamics of the plasma sheath in the substrate-to-target gap. In the case of an extremely late application of a high-voltage pulse, ions retained in the entire volume of the experimental chamber (as a result of the

Low-pressure pulsed focused ultrasound with microbubbles promotes an anticancer immunological response.

Science.gov (United States)

Liu, Hao-Li; Hsieh, Han-Yi; Lu, Li-An; Kang, Chiao-Wen; Wu, Ming-Fang; Lin, Chun-Yen

2012-11-11

High-intensity focused-ultrasound (HIFU) has been successfully employed for thermal ablation of tumors in clinical settings. Continuous- or pulsed-mode HIFU may also induce a host antitumor immune response, mainly through expansion of antigen-presenting cells in response to increased cellular debris and through increased macrophage activation/infiltration. Here we demonstrated that another form of focused ultrasound delivery, using low-pressure, pulsed-mode exposure in the presence of microbubbles (MBs), may also trigger an antitumor immunological response and inhibit tumor growth. A total of 280 tumor-bearing animals were subjected to sonographically-guided FUS. Implanted tumors were exposed to low-pressure FUS (0.6 to 1.4 MPa) with MBs to increase the permeability of tumor microvasculature. Tumor progression was suppressed by both 0.6 and 1.4-MPa MB-enhanced FUS exposures. We observed a transient increase in infiltration of non-T regulatory (non-Treg) tumor infiltrating lymphocytes (TILs) and continual infiltration of CD8+ cytotoxic T-lymphocytes (CTL). The ratio of CD8+/Treg increased significantly and tumor growth was inhibited. Our findings suggest that low-pressure FUS exposure with MBs may constitute a useful tool for triggering an anticancer immune response, for potential cancer immunotherapy.

Powerful nanosecond pulse train generator

International Nuclear Information System (INIS)

Isakov, I.F.; Logachev, E.I.; Opekunov, M.S.; Pechenkin, S.A.; Remnev, G.E.; Usov, Yu.P.

1987-01-01

A generator permitting to shape on the load pulsed with the repetition frequency of 10 3 -10 6 Hz and more is described. The amplitude of shaped voltage pulses is up to 150 kV at pulse duration equal to 50 ns. The generator comprises connected in-series with the load two shaping and two transmission lines realized on the base of the KVI-300 low-ohmic cable. The shaping lines are supplied from two independently connected pulse voltage generators for obtaining time interval between pulses > 10 -6 s; they may be also supplied from one generator for obtaining time interval -6 s. At the expense of reducing losses in the discharge circuit the amplitude of the second pulse grows with increase of time interval between pulses up to 300 ns, further on the curve flat-topping exists. The described generator is used in high-current accelerators, in which the primary negative pulse results in generation of explosive-emission plasma, and the second positive pulse provides ion beam shaping including ions of heavy metal used for production of a potential electrode. The generator multipulse mode is used for successive ion acceleration in the transport system

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

Science.gov (United States)

Wain, Louise V; Verwoert, Germaine C; O’Reilly, Paul F; Shi, Gang; Johnson, Toby; Johnson, Andrew D; Bochud, Murielle; Rice, Kenneth M; Henneman, Peter; Smith, Albert V; Ehret, Georg B; Amin, Najaf; Larson, Martin G; Mooser, Vincent; Hadley, David; Dörr, Marcus; Bis, Joshua C; Aspelund, Thor; Esko, Tõnu; Janssens, A Cecile JW; Zhao, Jing Hua; Heath, Simon; Laan, Maris; Fu, Jingyuan; Pistis, Giorgio; Luan, Jian’an; Arora, Pankaj; Lucas, Gavin; Pirastu, Nicola; Pichler, Irene; Jackson, Anne U; Webster, Rebecca J; Zhang, Feng; Peden, John F; Schmidt, Helena; Tanaka, Toshiko; Campbell, Harry; Igl, Wilmar; Milaneschi, Yuri; Hotteng, Jouke-Jan; Vitart, Veronique; Chasman, Daniel I; Trompet, Stella; Bragg-Gresham, Jennifer L; Alizadeh, Behrooz Z; Chambers, John C; Guo, Xiuqing; Lehtimäki, Terho; Kühnel, Brigitte; Lopez, Lorna M; Polašek, Ozren; Boban, Mladen; Nelson, Christopher P; Morrison, Alanna C; Pihur, Vasyl; Ganesh, Santhi K; Hofman, Albert; Kundu, Suman; Mattace-Raso, Francesco US; Rivadeneira, Fernando; Sijbrands, Eric JG; Uitterlinden, Andre G; Hwang, Shih-Jen; Vasan, Ramachandran S; Wang, Thomas J; Bergmann, Sven; Vollenweider, Peter; Waeber, Gérard; Laitinen, Jaana; Pouta, Anneli; Zitting, Paavo; McArdle, Wendy L; Kroemer, Heyo K; Völker, Uwe; Völzke, Henry; Glazer, Nicole L; Taylor, Kent D; Harris, Tamara B; Alavere, Helene; Haller, Toomas; Keis, Aime; Tammesoo, Mari-Liis; Aulchenko, Yurii; Barroso, Inês; Khaw, Kay-Tee; Galan, Pilar; Hercberg, Serge; Lathrop, Mark; Eyheramendy, Susana; Org, Elin; Sõber, Siim; Lu, Xiaowen; Nolte, Ilja M; Penninx, Brenda W; Corre, Tanguy; Masciullo, Corrado; Sala, Cinzia; Groop, Leif; Voight, Benjamin F; Melander, Olle; O’Donnell, Christopher J; Salomaa, Veikko; d’Adamo, Adamo Pio; Fabretto, Antonella; Faletra, Flavio; Ulivi, Sheila; Del Greco, M Fabiola; Facheris, Maurizio; Collins, Francis S; Bergman, Richard N; Beilby, John P; Hung, Joseph; Musk, A William; Mangino, Massimo; Shin, So-Youn; Soranzo, Nicole; Watkins, Hugh; Goel, Anuj; Hamsten, Anders; Gider, Pierre; Loitfelder, Marisa; Zeginigg, Marion; Hernandez, Dena; Najjar, Samer S; Navarro, Pau; Wild, Sarah H; Corsi, Anna Maria; Singleton, Andrew; de Geus, Eco JC; Willemsen, Gonneke; Parker, Alex N; Rose, Lynda M; Buckley, Brendan; Stott, David; Orru, Marco; Uda, Manuela; van der Klauw, Melanie M; Zhang, Weihua; Li, Xinzhong; Scott, James; Chen, Yii-Der Ida; Burke, Gregory L; Kähönen, Mika; Viikari, Jorma; Döring, Angela; Meitinger, Thomas; Davies, Gail; Starr, John M; Emilsson, Valur; Plump, Andrew; Lindeman, Jan H; ’t Hoen, Peter AC; König, Inke R; Felix, Janine F; Clarke, Robert; Hopewell, Jemma C; Ongen, Halit; Breteler, Monique; Debette, Stéphanie; DeStefano, Anita L; Fornage, Myriam; Mitchell, Gary F; Smith, Nicholas L; Holm, Hilma; Stefansson, Kari; Thorleifsson, Gudmar; Thorsteinsdottir, Unnur; Samani, Nilesh J; Preuss, Michael; Rudan, Igor; Hayward, Caroline; Deary, Ian J; Wichmann, H-Erich; Raitakari, Olli T; Palmas, Walter; Kooner, Jaspal S; Stolk, Ronald P; Jukema, J Wouter; Wright, Alan F; Boomsma, Dorret I; Bandinelli, Stefania; Gyllensten, Ulf B; Wilson, James F; Ferrucci, Luigi; Schmidt, Reinhold; Farrall, Martin; Spector, Tim D; Palmer, Lyle J; Tuomilehto, Jaakko; Pfeufer, Arne; Gasparini, Paolo; Siscovick, David; Altshuler, David; Loos, Ruth JF; Toniolo, Daniela; Snieder, Harold; Gieger, Christian; Meneton, Pierre; Wareham, Nicholas J; Oostra, Ben A; Metspalu, Andres; Launer, Lenore; Rettig, Rainer; Strachan, David P; Beckmann, Jacques S; Witteman, Jacqueline CM; Erdmann, Jeanette; van Dijk, Ko Willems; Boerwinkle, Eric; Boehnke, Michael; Ridker, Paul M; Jarvelin, Marjo-Riitta; Chakravarti, Aravinda; Abecasis, Goncalo R; Gudnason, Vilmundur; Newton-Cheh, Christopher; Levy, Daniel; Munroe, Patricia B; Psaty, Bruce M; Caulfield, Mark J; Rao, Dabeeru C

2012-01-01

Numerous genetic loci influence systolic blood pressure (SBP) and diastolic blood pressure (DBP) in Europeans 1-3. We now report genome-wide association studies of pulse pressure (PP) and mean arterial pressure (MAP). In discovery (N=74,064) and follow-up studies (N=48,607), we identified at genome-wide significance (P= 2.7×10-8 to P=2.3×10-13) four novel PP loci (at 4q12 near CHIC2/PDGFRAI, 7q22.3 near PIK3CG, 8q24.12 in NOV, 11q24.3 near ADAMTS-8), two novel MAP loci (3p21.31 in MAP4, 10q25.3 near ADRB1) and one locus associated with both traits (2q24.3 near FIGN) which has recently been associated with SBP in east Asians. For three of the novel PP signals, the estimated effect for SBP was opposite to that for DBP, in contrast to the majority of common SBP- and DBP-associated variants which show concordant effects on both traits. These findings indicate novel genetic mechanisms underlying blood pressure variation, including pathways that may differentially influence SBP and DBP. PMID:21909110

Acetylcysteine reduces plasma homocysteine concentration and improves pulse pressure and endothelial function in patients with end-stage renal failure

DEFF Research Database (Denmark)

Scholze, Alexandra; Rinder, Christiane; Beige, Joachim

2004-01-01

Increased oxidative stress, elevated plasma homocysteine concentration, increased pulse pressure, and impaired endothelial function constitute risk factors for increased mortality in patients with end-stage renal failure.......Increased oxidative stress, elevated plasma homocysteine concentration, increased pulse pressure, and impaired endothelial function constitute risk factors for increased mortality in patients with end-stage renal failure....

Non-invasive aortic systolic pressure and pulse wave velocity estimation in a primary care setting: An in silico study.

Science.gov (United States)

Guala, Andrea; Camporeale, Carlo; Ridolfi, Luca; Mesin, Luca

2017-04-01

Everyday clinical cardiovascular evaluation is still largely based on brachial systolic and diastolic pressures. However, several clinical studies have demonstrated the higher diagnostic capacities of the aortic pressure, as well as the need to assess the aortic mechanical properties (e.g., by measuring the aortic pulse wave velocity). In order to fill this gap, we propose to exploit a set of easy-to-obtain physical characteristics to estimate the aortic pressure and pulse wave velocity. To this aim, a large population of virtual subjects is created by a validated mathematical model of the cardiovascular system. Quadratic regressive models are then fitted and statistically selected in order to obtain reliable estimations of the aortic pressure and pulse wave velocity starting from the knowledge of the subject age, height, weight, brachial pressure, photoplethysmographic measures and either electrocardiogram or phonocardiogram. The results are very encouraging and foster clinical studies aiming to apply a similar technique to a real population. Copyright © 2017 IPEM. Published by Elsevier Ltd. All rights reserved.

The effects of pulse pressure from seismic water gun technology on Northern Pike

Science.gov (United States)

Gross, Jackson A.; Irvine, Kathryn M.; Wilmoth, Siri K.; Wagner, Tristany L.; Shields, Patrick A; Fox, Jeffrey R.

2013-01-01

We examined the efficacy of sound pressure pulses generated from a water gun for controlling invasive Northern Pike Esox lucius. Pulse pressures from two sizes of water guns were evaluated for their effects on individual fish placed at a predetermined random distance. Fish mortality from a 5,620.8-cm3 water gun (peak pressure source level = 252 dB referenced to 1 μP at 1 m) was assessed every 24 h for 168 h, and damage (intact, hematoma, or rupture) to the gas bladder, kidney, and liver was recorded. The experiment was replicated with a 1,966.4-cm3 water gun (peak pressure source level = 244 dB referenced to 1 μP at 1 m), but fish were euthanized immediately. The peak sound pressure level (SPLpeak), peak-to-peak sound pressure level (SPLp-p), and frequency spectrums were recorded, and the cumulative sound exposure level (SELcum) was subsequently calculated. The SPLpeak, SPLp-p, and SELcum were correlated, and values varied significantly by treatment group for both guns. Mortality increased and organ damage was greater with decreasing distance to the water gun. Mortality (31%) by 168 h was only observed for Northern Pike exhibiting the highest degree of organ damage. Mortality at 72 h and 168 h postexposure was associated with increasing SELcum above 195 dB. The minimum SELcum calculated for gas bladder rupture was 199 dB recorded at 9 m from the 5,620.8-cm3 water gun and 194 dB recorded at 6 m from the 1,966.4-cm3water gun. Among Northern Pike that were exposed to the large water gun, 100% of fish exposed at 3 and 6 m had ruptured gas bladders, and 86% exposed at 9 m had ruptured gas bladders. Among fish that were exposed to pulse pressures from the smaller water gun, 78% exhibited gas bladder rupture. Results from these initial controlled experiments underscore the potential of water guns as a tool for controlling Northern Pike.

Responses to amplitude modulated infrared stimuli in the guinea pig inferior colliculus

Science.gov (United States)

Richter, Claus-Peter; Young, Hunter

2013-03-01

Responses of units in the central nucleus of the inferior colliculus of the guinea pig were recorded with tungsten electrodes. The set of data presented here is limited to high stimulus levels. The effect of changing the modulation frequency and the modulation depth was explored for acoustic and laser stimuli. The selected units responded to sinusoidal amplitude modulated (AM) tones, AM trains of clicks, and AM trains of laser pulses with a modulation of their spike discharge. At modulation frequencies of 20 Hz, some units tended to respond with 40 Hz to the acoustic stimuli, but only at 20 Hz for the trains of laser pulses. For all modes of stimulation the responses revealed a dominant response to the first cycle of the modulation, with decreasing number of action potential during successive cycles. While amplitude modulated tone bursts and amplitude modulated trains of acoustic clicks showed similar patterns, the response to trains of laser pulses was different.

Carbon dioxide reforming of methane by atmospheric pressure pulsed glow discharge: The effect of pulse compression

International Nuclear Information System (INIS)

Ghorbanzadeh, A.; Modarresi, H.

2006-01-01

Methane reforming by carbon dioxide in atmospheric pressure pulsed glow discharge was examined. The pulse duration of plasma was compressed to ∼50 ns or lower. This compression allowed working at higher frequencies, more than 3 k Hz, without glow to arc transition. The main outlet gases were synthetic gases (H 2 , CO) and C 2 (ethylene, ethane, and acetylene) products. At equal reactants proportion CO 2 /CH 4 =1, about 42 p ercent o f plasma energy went to chemical dissociation while reactant conversions were relatively high, i.e. near 55 p ercent % (CH 4 ) and 42 p ercent ( CO 2 ). At this point, the energy expenditure was less than 3.8 eV per each converted molecule. The reactor energy performance even gets better at higher CO 2 /CH 4 proportions. At CO 2 /CH 4 =5, The conversions of about 65 p ercent a nd 45 p ercent w ere obtained for methane and carbon dioxide respectively, while energy efficiency reached near 45 p ercent . It is discussed that high nonequilibrium state of vibrational energy at short pulses, especially in carbon dioxide, leads to this improvement.

Temperature and Pressure Dependence of Signal Amplitudes for Electrostriction Laser-Induced Thermal Acoustics

Science.gov (United States)

Herring, Gregory C.

2015-01-01

The relative signal strength of electrostriction-only (no thermal grating) laser-induced thermal acoustics (LITA) in gas-phase air is reported as a function of temperature T and pressure P. Measurements were made in the free stream of a variable Mach number supersonic wind tunnel, where T and P are varied simultaneously as Mach number is varied. Using optical heterodyning, the measured signal amplitude (related to the optical reflectivity of the acoustic grating) was averaged for each of 11 flow conditions and compared to the expected theoretical dependence of a pure-electrostriction LITA process, where the signal is proportional to the square root of [P*P /( T*T*T)].

Robust motion artefact resistant circuit for calculation of Mean Arterial Pressure from pulse transit time.

Science.gov (United States)

Bhattacharya, Tinish; Gupta, Ankesh; Singh, Salam ThoiThoi; Roy, Sitikantha; Prasad, Anamika

2017-07-01

Cuff-less and non-invasive methods of Blood Pressure (BP) monitoring have faced a lot of challenges like stability, noise, motion artefact and requirement for calibration. These factors are the major reasons why such devices do not get approval from the medical community easily. One such method is calculating Blood Pressure indirectly from pulse transit time (PTT) obtained from electrocardiogram (ECG) and Photoplethysmogram (PPG). In this paper we have proposed two novel analog signal conditioning circuits for ECG and PPG that increase stability, remove motion artefacts, remove the sinusoidal wavering of the ECG baseline due to respiration and provide consistent digital pulses corresponding to blood pulses/heart-beat. We have combined these two systems to obtain the PTT and then correlated it with the Mean Arterial Pressure (MAP). The aim was to perform major part of the processing in analog domain to decrease processing load over microcontroller so as to reduce cost and make it simple and robust. We have found from our experiments that the proposed circuits can calculate the Heart Rate (HR) with a maximum error of ~3.0% and MAP with a maximum error of ~2.4% at rest and ~4.6% in motion.

Effects of oxygen gas pressure on properties of iron oxide films grown by pulsed laser deposition

International Nuclear Information System (INIS)

Guo, Qixin; Shi, Wangzhou; Liu, Feng; Arita, Makoto; Ikoma, Yoshifumi; Saito, Katsuhiko; Tanaka, Tooru; Nishio, Mitsuhiro

2013-01-01

Highlights: ► Pulsed laser deposition is a promising technique for growing iron oxide films. ► Crystal structure of the iron oxide films strongly depends on oxygen gas pressure. ► Optimum of the oxygen gas pressure leads single phase magnetite films with high crystal quality. -- Abstract: Iron oxide films were grown on sapphire substrates by pulsed laser deposition at oxygen gas pressures between 1 × 10 −5 and 1 × 10 −1 Pa with a substrate temperature of 600 °C. Atomic force microscope, X-ray diffraction, Raman spectroscopy, X-ray absorption fine structure, and vibrational sample magnetometer analysis revealed that surface morphology and crystal structure of the iron oxide films strongly depend on the oxygen gas pressure during the growth and the optimum oxygen gas pressure range is very narrow around 1 × 10 −3 Pa for obtaining single phase magnetite films with high crystal quality

Removal of residual nuclei following a cavitation event using low-amplitude ultrasound.

Science.gov (United States)

Duryea, Alexander P; Cain, Charles A; Tamaddoni, Hedieh A; Roberts, William W; Hall, Timothy L

2014-10-01

Microscopic residual bubble nuclei can persist on the order of 1 s following a cavitation event. These bubbles can limit the efficacy of ultrasound therapies such as shock wave lithotripsy and histotripsy, because they attenuate pulses that arrive subsequent to their formation and seed repetitive cavitation activity at a discrete set of sites (cavitation memory). Here, we explore a strategy for the removal of these residual bubbles following a cavitation event, using low-amplitude ultrasound pulses to stimulate bubble coalescence. All experiments were conducted in degassed water and monitored using high-speed photography. In each case, a 2-MHz histotripsy transducer was used to initiate cavitation activity (a cavitational bubble cloud), the collapse of which generated a population of residual bubble nuclei. This residual nuclei population was then sonicated using a 1 ms pulse from a separate 500-kHz transducer, which we term the bubble removal pulse. Bubble removal pulse amplitudes ranging from 0 to 1.7 MPa were tested, and the backlit area of shadow from bubbles remaining in the field following bubble removal was calculated to quantify efficacy. It was found that an ideal amplitude range exists (roughly 180 to 570 kPa) in which bubble removal pulses stimulate the aggregation and subsequent coalescence of residual bubble nuclei, effectively removing them from the field. Further optimization of bubble removal pulse sequences stands to provide an adjunct to cavitation-based ultrasound therapies such as shock wave lithotripsy and histotripsy, mitigating the effects of residual bubble nuclei that currently limit their efficacy.

Synchronization circuit for shaping electron beam picosecond pulses

International Nuclear Information System (INIS)

Pavlov, Yu.S.; Solov'ev, N.G.; Tomnikov, A.P.

1985-01-01

A fast response circuit of modulator trigger pulse synchronization of a deflector of the electron linear accelerator at 13 MeV with the given phase of HF-voltage is described. The circuit is constructed using K500 and K100 integrated emitter-coupled logics circuits. Main parameters of a synchropulse are duration of 20-50 ns, pulse rise time of 1-5 ns, pulse amplitude >=10 V, delay instability of a trigger pulse <=+-0.05 ns. A radiopulse with 3 μs duration, 5 V amplitude and 400 Hz frequency enters the circuit input. The circuit can operate at both pulsed operation and continuous modes

Phase and amplitude detection system for the Stanford Linear Accelerator

International Nuclear Information System (INIS)

Fox, J.D.; Schwarz, H.D.

1983-01-01

A computer controlled phase and amplitude detection system to measure and stabilize the rf power sources in the Stanford Linear Accelerator is described. This system measures the instantaneous phase and amplitude of a 1 microsecond 2856 MHz rf pulse and will be used for phase feedback control and for amplitude and phase jitter detection. This paper discusses the measurement system performance requirements for the operation of the Stanford Linear Collider, and the design and implementation of the phase and amplitude detection system. The fundamental software algorithms used in the measurement are described, as is the performance of the prototype phase and amplitude detector system

On random pressure pulses in the turbine draft tube

Science.gov (United States)

Kuibin, P. A.; Shtork, S. I.; Skripkin, S. G.; Tsoy, M. A.

2017-04-01

The flow in the conical part of the hydroturbine draft tube undergoes various instabilities due to deceleration and flow swirling at off-design operation points. In particular, the precessing vortex rope develops at part-load regimes in the draft tube. This rope induces periodical low-frequency pressure oscillations in the draft tube. Interaction of rotational (asynchronous) mode of disturbances with the elbow can bring to strong oscillations in the whole hydrodynamical system. Recent researches on flow structure in the discharge cone in a regime of free runner had revealed that helical-like vortex rope can be unstable itself. Some coils of helix close to each other and reconnection appears with generation of a vortex ring. The vortex ring moves toward the draft tube wall and downstream. The present research is focused on interaction of vortex ring with wall and generation of pressure pulses.

On the propagation of the pressure pulse due to an unconfined gas cloud explosion

International Nuclear Information System (INIS)

Essers, J.A.

1985-01-01

A critical analysis of flow models used in computer codes for the simulation of the propagation in air of a pressure pulse due to a gas cloud explosion is presented. In particular, weaknesses of simple linear acoustic model are pointed out, and a more reliable non-linear isentropic model is proposed. A simple one-dimensional theory is used to evaluate as a function of the relative overpressure the speed of an incident normal shock-wave, as well as the strength and speed of the wave after reflection on a simplified rigid obstacle. Results obtained with the different models are compared to those obtained from the full Euler equations. A theoretical analysis of pulse deformation during its propagation is presented, and the ability of each model to correctly simulate that purely non-linear phenomenon is discussed. In particular, the formation of a sharp pressure pulse (shock-up phenomenon) is analyzed in detail. From the analysis, the accuracy of the linear acoustic model for the evaluation of strength and speed of incident and reflected waves is found to be quite poor except for very weak overpressures. Additionally, such a model is completely unable to simulate pulse deformations. As a result, it should be expected to lead to important errors in the simulation of pulse interaction with non-rigid obstacles, even at very weak overpressures. As opposed to that very simple model, the proposed non-linear isentropic model is found to lead to an excellent accuracy in the prediction of all wave characteristics mentioned above and in the simulation of pulse deformation if overpressure is not too large. (author)

Evaluation of dynamic range for LLNL streak cameras using high contrast pulses and pulse podiatry'' on the Nova laser system

Energy Technology Data Exchange (ETDEWEB)

Richards, J.B.; Weiland, T.L.; Prior, J.A.

1990-07-01

A standard LLNL streak camera has been used to analyze high contrast pulses on the Nova laser facility. These pulses have a plateau at their leading edge (foot) with an amplitude which is approximately 1% of the maximum pulse height. Relying on other features of the pulses and on signal multiplexing, we were able to determine how accurately the foot amplitude was being represented by the camera. Results indicate that the useful single channel dynamic range of the instrument approaches 100:1. 1 ref., 4 figs., 1 tab.

A 16.3 pJ/pulse low-complexity and energy-efficient transmitter with adjustable pulse parameters

International Nuclear Information System (INIS)

Jiang Jun; Zhao Yi; Shao Ke; Chen Hu; Xia Lingli; Hong Zhiliang

2011-01-01

This paper presents a novel, fully integrated transmitter for 3-5 GHz pulsed UWB. The BPSK modulation transmitter has been implemented in SMIC CMOS 0.13 μm technology with a 1.2-V supply voltage and a die size of 0.8 x 0.95 mm 2 . This transmitter is based on the impulse response filter method, which uses a tunable R paralleled with a LC frequency selection network to realize continuously adjustable pulse parameters, including bandwidth, width and amplitude. Due to the extremely low duty of the pulsed UWB, a proposed output buffer is employed to save power consumption significantly. Finally, measurement results show that the transmitter consumes only 16.3 pJ/pulse to achieve a pulse repetition rate of 100 Mb/s. Generated pulses strictly comply with the FCC spectral mask. The continuously variable pulse width is from 900 to 1.5 ns and the amplitude with the minimum 178 mVpp and the maximum 432 mVpp can be achieved. (semiconductor integrated circuits)

Pulse pressure and nocturnal fall in blood pressure are predictors of vascular, cardiac and renal target organ damage in hypertensive patients (LOD-RISK study).

Science.gov (United States)

García-Ortiz, Luis; Gómez-Marcos, Manuel A; Martín-Moreiras, Javier; González-Elena, Luis J; Recio-Rodriguez, Jose I; Castaño-Sánchez, Yolanda; Grandes, Gonzalo; Martínez-Salgado, Carlos

2009-08-01

To analyse the relationship between various parameters derived from ambulatory blood pressure monitoring (ABPM) and vascular, cardiac and renal target organ damage. A cross-sectional, descriptive study. It included 353 patients with short-term or recently diagnosed hypertension. ABPM, carotid intima-media thickness (IMT), Cornell voltage-duration product (Cornell VDP), glomerular filtration rate and albumin/creatinine ratio to assess vascular, cardiac and renal damage. Two hundred and twenty-three patients (63.2%) were males, aged 56.12+/-11.21 years. The nocturnal fall in blood pressure was 11.33+/-8.41, with a dipper pattern in 49.0% (173), nondipper in 30.3% (107), extreme dipper in 12.7% (45) and riser in 7.9% (28). The IMT was lower in the extreme dipper (0.716+/-0.096 mm) and better in the riser pattern (0.794+/-0.122 mm) (P<0.05). The Cornell VDP and albumin/creatinine ratio were higher in the riser pattern (1818.94+/-1798.63 mm/ms and 140.78+/-366.38 mg/g, respectively) than in the other patterns. In the multivariate analysis after adjusting for age, sex and antihypertensive treatment, with IMT as dependent variable the 24-h pulse pressure (beta = 0.003), with Cornell VDP the rest pulse pressure (beta = 12.04), and with the albumin/creatinine ratio the percentage of nocturnal fall in systolic blood pressure (beta = -3.59), the rest heart rate (beta = 1.83) and the standard deviation of 24-h systolic blood pressure (beta = 5.30) remain within the equation. The estimated pulse pressure with ABPM is a predictor of vascular and cardiac organ damage. The nocturnal fall and the standard deviation in 24-h systolic blood pressure measured with the ABPM is a predictor of renal damage.

Pulsed, atmospheric pressure plasma source for emission spectrometry

Science.gov (United States)

Duan, Yixiang; Jin, Zhe; Su, Yongxuan

2004-05-11

A low-power, plasma source-based, portable molecular light emission generator/detector employing an atmospheric pressure pulsed-plasma for molecular fragmentation and excitation is described. The average power required for the operation of the plasma is between 0.02 W and 5 W. The features of the optical emission spectra obtained with the pulsed plasma source are significantly different from those obtained with direct current (dc) discharge higher power; for example, strong CH emission at 431.2 nm which is only weakly observed with dc plasma sources was observed, and the intense CN emission observed at 383-388 nm using dc plasma sources was weak in most cases. Strong CN emission was only observed using the present apparatus when compounds containing nitrogen, such as aniline were employed as samples. The present apparatus detects dimethylsulfoxide at 200 ppb using helium as the plasma gas by observing the emission band of the CH radical. When coupled with a gas chromatograph for separating components present in a sample to be analyzed, the present invention provides an apparatus for detecting the arrival of a particular component in the sample at the end of the chromatographic column and the identity thereof.

High-voltage short-fall pulse generator

International Nuclear Information System (INIS)

Dolbilov, G.V.; Fateev, A.A.; Petrov, V.A.

1986-01-01

Powerful high-voltage pulses with short fall times and relatively low afterpulse amplitude are required for the deflection systems of accelerators. A generator is described that provides, into a 75-ohm load, a voltage pulse of up to 100 kV with a fall time of less than 1 nsec and a relative afterpulse amplitude of less than or equal to 15%. The generator employs a short-circuited ferrite-filled line in which shock waves are formed. A magnetic section is used to increase power. The switch is a TGI1-2500/50 thyratron. The main causes of afterpulses and methods for reducing their amplitude are examined

Objectives and configuration of the Multiple Pulse Propagation Experiment

International Nuclear Information System (INIS)

Orzechowski, T.J.; Caporaso, G.J.; Chamber, F.W.; Chong, Y.P.; Deadrick, F.J.; Guethlein, G.; Fawley, W.M.; Renbarger, V.L.; Rogers, D. Jr.; Weir, J.T.; Eckstrom, D.; Stalder, K.; Hubbard, R.; Lee, P.

1990-01-01

The Multiple Pulse Propagation Experiment (MPPE) was designed to determine the hose stability properties of an intense relativistic electron beam in a beam generated density channel and to investigate range extension with increasing pulse number in the burst. This experiment used a 10-MeV electron beam generated by the Advanced Test Accelerator (ATA). The electron beam current was expected to be at least 6-kA with an equilibrium radius of 0.5 cm (RMS) in the gas. This last constraint implied an unnormalized, RMS beam emittance of 20 mrad-cm. In order to achieve beam stability against hose, each electron beam pulse had to be tailored in emittance in order to phase mix damp the instability. The initial offsets of the beam were to be kept small in order to prevent a large saturated amplitude. Numerical simulations determined the initial criteria for the emittance profile and initial beam displacements. In order to demonstrate a final density depression of 25% of ambient pressure, at least five pulses with interpulse separation of 1- to 2-ms were specified

Experimental study on vapor explosion induced by pressure pulse in coarse mixing of hot molten metal and water

International Nuclear Information System (INIS)

Inoue, A.; Tobita, Y.; Aritomi, M.; Takahashi, M.; Matsuzaki, M.

2004-01-01

An experimental study was done to investigate characteristics of metal-water interaction, when a mount of hot liquid metal is injected into the water. The test section is a vertical shock tube of 60mm in inner diameter and 1200mm in length. A special injector which is designed to inject hot metal of controlled volume and flow rate is attached at the top of the tube. When the hot metal is injected in the water and comes down at a position of the test vessel, a trigger pressure pulse is generated at the bottom of the test tube. Local transient pressures along the tube are measured by piezo pressure transducers. The following items were investigated in the experiment; 1) The criteria to cause a vapor explosion, 2) Transient behaviors and propagation characteristics of pressure wave in the mixing region. 3) Effects of triggering pulse, injection temperature and mass of hot molten metal on the peak pressure. The probability of the vapor explosion jumped when the interface temperature at the molten metal-water direct contact is higher than the homogeneous nucleation temperature of water and the triggering pulse becomes larger than 0.9MPa. Two types of the pressure propagation modes are observed, one is the detonative mode with a sharp rise and other is usual pressure mode with a mild rise. (author)

Applicability of Pulse Pressure Variation during Unstable Hemodynamic Events in the Intensive Care Unit: A Five-Day Prospective Multicenter Study

Directory of Open Access Journals (Sweden)

Bertrand Delannoy

2016-01-01

Full Text Available Pulse pressure variation can predict fluid responsiveness in strict applicability conditions. The purpose of this study was to describe the clinical applicability of pulse pressure variation during episodes of patient hemodynamic instability in the intensive care unit. We conducted a five-day, seven-center prospective study that included patients presenting with an unstable hemodynamic event. The six predefined inclusion criteria for pulse pressure variation applicability were as follows: mechanical ventilation, tidal volume >7 mL/kg, sinus rhythm, no spontaneous breath, heart rate/respiratory rate ratio >3.6, absence of right ventricular dysfunction, or severe valvulopathy. Seventy-three patients presented at least one unstable hemodynamic event, with a total of 163 unstable hemodynamic events. The six predefined criteria for the applicability of pulse pressure variation were completely present in only 7% of these. This data indicates that PPV should only be used alongside a strong understanding of the relevant physiology and applicability criteria. Although these exclusion criteria appear to be profound, they likely represent an absolute contraindication of use for only a minority of critical care patients.

Resolving the contribution of the uncoupled phycobilisomes to cyanobacterial pulse-amplitude modulated (PAM) fluorometry signals.

Science.gov (United States)

Acuña, Alonso M; Snellenburg, Joris J; Gwizdala, Michal; Kirilovsky, Diana; van Grondelle, Rienk; van Stokkum, Ivo H M

2016-01-01

Pulse-amplitude modulated (PAM) fluorometry is extensively used to characterize photosynthetic organisms on the slow time-scale (1-1000 s). The saturation pulse method allows determination of the quantum yields of maximal (F(M)) and minimal fluorescence (F(0)), parameters related to the activity of the photosynthetic apparatus. Also, when the sample undergoes a certain light treatment during the measurement, the fluorescence quantum yields of the unquenched and the quenched states can be determined. In the case of cyanobacteria, however, the recorded fluorescence does not exclusively stem from the chlorophyll a in photosystem II (PSII). The phycobilins, the pigments of the cyanobacterial light-harvesting complexes, the phycobilisomes (PB), also contribute to the PAM signal, and therefore, F(0) and F(M) are no longer related to PSII only. We present a functional model that takes into account the presence of several fluorescent species whose concentrations can be resolved provided their fluorescence quantum yields are known. Data analysis of PAM measurements on in vivo cells of our model organism Synechocystis PCC6803 is discussed. Three different components are found necessary to fit the data: uncoupled PB (PB(free)), PB-PSII complexes, and free PSI. The free PSII contribution was negligible. The PB(free) contribution substantially increased in the mutants that lack the core terminal emitter subunits allophycocyanin D or allophycocyanin F. A positive correlation was found between the amount of PB(free) and the rate constants describing the binding of the activated orange carotenoid protein to PB, responsible for non-photochemical quenching.

Effect of gas heating on the generation of an ultrashort avalanche electron beam in the pulse-periodic regime

Science.gov (United States)

Baksht, E. Kh.; Burachenko, A. G.; Lomaev, M. I.; Sorokin, D. A.; Tarasenko, V. F.

2015-07-01

The generation of an ultrashort avalanche electron beam (UAEB) in nitrogen in the pulse-periodic regime is investigated. The gas temperature in the discharge gap of the atmospheric-pressure nitrogen is measured from the intensity distribution of unresolved rotational transitions ( C 3Π u , v' = 0) → ( B 3Π g , v″ = 0) in the nitrogen molecule for an excitation pulse repetition rate of 2 kHz. It is shown that an increase in the UAEB current amplitude in the pulse-periodic regime is due to gas heating by a series of previous pulses, which leads to an increase in the reduced electric field strength as a result of a decrease in the gas density in the zone of the discharge formation. It is found that in the pulse-periodic regime and the formation of the diffuse discharge, the number of electrons in the beam increases by several times for a nitrogen pressure of 9 × 103 Pa. The dependences of the number of electrons in the UAEB on the time of operation of the generator are considered.

Electronic system for recording proportional counter rare pulses with the pulse shape analysis

International Nuclear Information System (INIS)

Barabanov, I.R.; Gavrin, V.N.; Zakharov, Yu.I.; Tikhonov, A.A.

1984-01-01

The anutomated system for recording proportional counter rare pulses is described. The proportional counters are aimed at identification of 37 Ar and H7 1 Gr decays in chemical radiation detectors of solar neutrino. Pulse shape recording by means of a storage oscilloscope and a TV display is performed in the system considered besides two-parametric selection of events (measurement of pulse amplitude in a slow channel and the amplitude of pulse differentiated with time constant of about 10 ns in a parallel fast channel). Pulse discrimination by a front rise rate provides background decrease in the 55 Fe range (5.9 keV) by 6 times; the visual analysis of pulse shapes recorded allows to decrease the background additionally by 25-30%. The background counting rate in the 55 Fe range being equal to 1 pulse per 1.5 days, is obtained when using the installation described above, as well as the passive Pb shield 5 cm thick, and the active shield based on the anticoincidence NaI(Tl) detector with the cathode 5.6 mm in-diameter made of Fe fabircated by zone melting. The installation described allows to reach the background level of 0.6 pulse/day (the total coefficient of background attenuation is 400). Further background decrease is supposed to be provided by installation allocation in the low-noise underground laboratory of the Baksan Neutrino Observatory

Modeling of Pulses Having Arbitrary Amplitude and Frequency Modulation.

Science.gov (United States)

1980-03-01

function, fi(t), has been discussed in great detail in Section II. The linearized amplitude modulation, 1(t), is given by: (IV-6) vo A +h( -) TO’ # where "A...10. LCDR Francis Martin Lunney, USN 6143 Gatsby Green Columbia, Maryland 21045 149

Twenty-Four-Hour Central Pulse Pressure for Cardiovascular Events Prediction in a Low-Cardiovascular-Risk Population: Results From the Bordeaux Cohort.

Science.gov (United States)

Cremer, Antoine; Boulestreau, Romain; Gaillard, Prune; Lainé, Marion; Papaioannou, Georgios; Gosse, Philippe

2018-02-23

Central blood pressure (BP) is a promising marker to identify subjects with higher cardiovascular risk than expected by traditional risk factors. Significant results have been obtained in populations with high cardiovascular risk, but little is known about low-cardiovascular-risk patients, although the differences between central and peripheral BP (amplification) are usually greater in this population. The study aim was to evaluate central BP over 24 hours for cardiovascular event prediction in hypertensive subjects with low cardiovascular risk. Peripheral and central BPs were recorded during clinical visits and over 24 hours in hypertensive patients with low cardiovascular risk (Systematic Coronary Risk Evaluation ≤5%). Our primary end point is the occurrence of a cardiovascular event during follow-up. To assess the potential interest in central pulse pressure over 24 hours, we performed Cox proportional hazard models analysis and comparison of area under the curves using the contrast test for peripheral and central BP. A cohort of 703 hypertensive subjects from Bordeaux were included. After the first 24 hours of BP measurement, the subjects were then followed up for an average of 112.5±70 months. We recorded 65 cardiovascular events during follow-up. Amplification was found to be significantly associated with cardiovascular events when added to peripheral 24-hour pulse pressure ( P =0.0259). The area under the curve of 24-hour central pulse pressure is significantly more important than area under the curve of office BP ( P =0.0296), and there is a trend of superiority with the area under the curve of peripheral 24-hour pulse pressure. Central pulse pressure over 24 hours improves the prediction of cardiovascular events for hypertensive patients with low cardiovascular risk compared to peripheral pulse pressure. © 2018 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

Evaluated Rayleigh integrals for pulsed planar expanding ring sources

International Nuclear Information System (INIS)

Warshaw, S.I.

1985-01-01

Time-domain analytic and semianalytic pressure fields acoustically radiated from expanding pulsed ring sources imbedded in a planar rigid baffle have been calculated. The source functions are radially symmetric delta-function distributions whose amplitude and argument have simple functional dependencies on radius and time. Certain cases yield closed analytic results, while others result in elliptic integrals, which are evaluated to high accuracy by Gauss-Chebyshev and modified Gauss-Legendre quadrature. These results are of value for calibrating computer simulations and convolution procedures, and estimating fields from more complex planar radiators. 3 refs., 4 figs

Sensitive detection of acrolein and acrylonitrile with a pulsed quantum-cascade laser

Science.gov (United States)

Manne, J.; Lim, A.; Tulip, J.; Jäger, W.

2012-05-01

We report on spectroscopic measurements of acrolein and acrylonitrile at atmospheric pressure using a pulsed distributed feedback quantum-cascade laser in combination with intra- and inter-pulse techniques and compare the results. The measurements were done in the frequency region around 957 cm-1. In the inter-pulse technique, the laser is excited with short current pulses (5-10 ns), and the pulse amplitude is modulated with an external current ramp resulting in a ˜2.3 cm-1 frequency scan. In the intra-pulse technique, a linear frequency down-chirp during the pulse is used for sweeping across the absorption line. Long current pulses up to 500 ns were used for these measurements which resulted in a spectral window of ˜2.2 cm-1 during the down-chirp. These comparatively wide spectral windows facilitated the measurements of the relatively broad absorption lines (˜1 cm-1) of acrolein and acrylonitrile. The use of a room-temperature mercury-cadmium-telluride detector resulted in a completely cryogen-free spectrometer. We demonstrate ppb level detection limits within a data acquisition time of ˜10 s with these methodologies.

Subharmonic emissions from microbubbles: effect of the driving pulse shape.

Science.gov (United States)

Biagi, Elena; Breschi, Luca; Vannacci, Enrico; Masotti, Leonardo

2006-11-01

The aims of this work are to investigate the response of the ultrasonic contrast agents (UCA) insonified by different arbitrary-shaped pulses at different acoustic pressures and concentration of the contrast agent focusing on subharmonic emission. A transmission setup was developed in order to insonify the contrast agent contained in a measurement chamber. The transmitted ultrasonic signals were generated by an arbitrary wave generator connected to a linear power amplifier able to drive a single-element transducer. The transmitted ultrasonic pulses that passed through the contrast agent-filled chamber were received by a second transducer or a hydrophone aligned with the first one. The radio frequency (RF) signals were acquired by fast echographic multiparameters multi-image novel apparatus (FEMMINA), which is an echographic platform able to acquire ultrasonic signals in a real-time modality. Three sets of ultrasonic signals were devised in order to evaluate subharmonic response of the contrast agent respect with sinusoidal burst signals used as reference pulses. A decreasing up to 30 dB in subharmonic response was detected for a Gaussian-shaped pulse; differences in subharmonic emission up to 21 dB were detected for a composite pulse (two-tone burst) for different acoustic pressures and concentrations. Results from this experimentation demonstrated that the transmitted pulse shape strongly affects subharmonic emission in spite of a second harmonic one. In particular, the smoothness of the initial portion of the shaped pulses can inhibit subharmonic generation from the contrast agents respect with a reference sinusoidal burst signal. It also was shown that subharmonic generation is influenced by the amplitude and the concentration of the contrast agent for each set of the shaped pulses. Subharmonic emissions that derive from a nonlinear mechanism involving nonlinear coupling among different oscillation modes are strongly affected by the shape of the ultrasonic

Bruce and Darlington power pulse and pressure tube integrity programs -status 1995

Energy Technology Data Exchange (ETDEWEB)

Field, G J [Atomic Energy of Canada Ltd., Mississauga, ON (Canada); Wylie, J [Ontario Hydro, Tiverton, ON (Canada). Bruce Nuclear Generating Station-A

1996-12-31

The optimum solution to pressure tube fretting at the inlet of the Bruce and Darlington channels, a concern which became very serious following inspections in early 1992, is to remove the inlet bundle and operate with a 12 fuel bundle channel. During analysis of this operating mode a `power pulse` was identified which could occur during an inlet header break where all the fuel in the channel moved rapidly to the inlet of the channel. The pulse was unacceptable and the units were derated until solutions could be implemented. A number of solutions were identified and each station has begun implementation of their specific solution. Implementation has not been without problems and this paper provides a status report on the progress to date of the long bundle implementation solution for Bruce B and Darlington and the fuelling with the flow solution being implemented at Bruce A. Both types of solution have a significant impact on the original concern, fretting of the pressure tube. (author). 1 ref., 6 figs.

Nanosecond repetitively pulsed discharges in air at atmospheric pressure-the spark regime

International Nuclear Information System (INIS)

Pai, David Z; Lacoste, Deanna A; Laux, Christophe O

2010-01-01

Nanosecond repetitively pulsed (NRP) spark discharges have been studied in atmospheric pressure air preheated to 1000 K. Measurements of spark initiation and stability, plasma dynamics, gas temperature and current-voltage characteristics of the spark regime are presented. Using 10 ns pulses applied repetitively at 30 kHz, we find that 2-400 pulses are required to initiate the spark, depending on the applied voltage. Furthermore, about 30-50 pulses are required for the spark discharge to reach steady state, following initiation. Based on space- and time-resolved optical emission spectroscopy, the spark discharge in steady state is found to ignite homogeneously in the discharge gap, without evidence of an initial streamer. Using measured emission from the N 2 (C-B) 0-0 band, it is found that the gas temperature rises by several thousand Kelvin in the span of about 30 ns following the application of the high-voltage pulse. Current-voltage measurements show that up to 20-40 A of conduction current is generated, which corresponds to an electron number density of up to 10 15 cm -3 towards the end of the high-voltage pulse. The discharge dynamics, gas temperature and electron number density are consistent with a streamer-less spark that develops homogeneously through avalanche ionization in volume. This occurs because the pre-ionization electron number density of about 10 11 cm -3 produced by the high frequency train of pulses is above the critical density for streamer-less discharge development, which is shown to be about 10 8 cm -3 .

Nanosecond repetitively pulsed discharges in air at atmospheric pressure-the spark regime

Energy Technology Data Exchange (ETDEWEB)

Pai, David Z; Lacoste, Deanna A; Laux, Christophe O [Laboratoire EM2C, CNRS UPR288, Ecole Centrale Paris, 92295 Chatenay-Malabry (France)

2010-12-15

Nanosecond repetitively pulsed (NRP) spark discharges have been studied in atmospheric pressure air preheated to 1000 K. Measurements of spark initiation and stability, plasma dynamics, gas temperature and current-voltage characteristics of the spark regime are presented. Using 10 ns pulses applied repetitively at 30 kHz, we find that 2-400 pulses are required to initiate the spark, depending on the applied voltage. Furthermore, about 30-50 pulses are required for the spark discharge to reach steady state, following initiation. Based on space- and time-resolved optical emission spectroscopy, the spark discharge in steady state is found to ignite homogeneously in the discharge gap, without evidence of an initial streamer. Using measured emission from the N{sub 2} (C-B) 0-0 band, it is found that the gas temperature rises by several thousand Kelvin in the span of about 30 ns following the application of the high-voltage pulse. Current-voltage measurements show that up to 20-40 A of conduction current is generated, which corresponds to an electron number density of up to 10{sup 15} cm{sup -3} towards the end of the high-voltage pulse. The discharge dynamics, gas temperature and electron number density are consistent with a streamer-less spark that develops homogeneously through avalanche ionization in volume. This occurs because the pre-ionization electron number density of about 10{sup 11} cm{sup -3} produced by the high frequency train of pulses is above the critical density for streamer-less discharge development, which is shown to be about 10{sup 8} cm{sup -3}.

Comparing the Effect of Labetalol versus Morphine on Controlling Blood Pressure and Pulse Rate During Emergence from Anesthesia after Craniotomy

Directory of Open Access Journals (Sweden)

Mohammadali Attari

2017-01-01

Full Text Available Background: Emergence from anesthesia is associated with sympathetic stimulation, increase in pulse and blood pressure. There are different methods, but the most appropriate method should be selected regarding the differences in nationalities. This study aimed to compare the efficacy of morphine and labetalol in controlling blood pressure and pulse during emergence from anesthesia in brain tumors craniotomy. Materials and Methods: This study was conducted at Al-Zahra Hospital of Isfahan - Iran on 60 patients suffering from brain tumor candidated for craniotomy and randomly classified into two groups of 30. One group received labetalol with dose of 10 mg over 10 min from 45 min before finishing dressing and then 0.75 mg/min until 35 min later; another group received morphine in bolus dose of 0.1 mg/kg during 2–3 min. Blood pressure and pulse were measured every 10 min over 40 min. After operation, they were measured every 5 min over 15 min. Results: The morphine group had higher systolic (133.3 ± 18.8 and diastolic blood pressure (87.1 ± 13.6 (P = 0.021 and 0.028, respectively at extubation and during 45 min before dressing, the diastolic blood pressure was significantly higher in compares with labetalol (75.3 ± 10.5 (P < 0.05. And extubation time was significantly shorter in labetalol group (7.7 ± 0.84 (P < 0.001. Pulse had no significant difference in both groups. In labetalol group, blood pressure and pulse fluctuations were more stable. Conclusion: Administration of labetalol 45 min before finishing dressing can significantly control blood pressure during emergence from anesthesia and also shorten the time of extubation during emergence in patients undergoing craniotomy.

AUTOMATIC DETECTION ALGORITHM OF DYNAMIC PRESSURE PULSES IN THE SOLAR WIND

International Nuclear Information System (INIS)

Zuo, Pingbing; Feng, Xueshang; Wang, Yi; Xie, Yanqiong; Li, Huijun; Xu, Xiaojun

2015-01-01

Dynamic pressure pulses (DPPs) in the solar wind are a significant phenomenon closely related to the solar-terrestrial connection and physical processes of solar wind dynamics. In order to automatically identify DPPs from solar wind measurements, we develop a procedure with a three-step detection algorithm that is able to rapidly select DPPs from the plasma data stream and simultaneously define the transition region where large dynamic pressure variations occur and demarcate the upstream and downstream region by selecting the relatively quiet status before and after the abrupt change in dynamic pressure. To demonstrate the usefulness, efficiency, and accuracy of this procedure, we have applied it to the Wind observations from 1996 to 2008 by successfully obtaining the DPPs. The procedure can also be applied to other solar wind spacecraft observation data sets with different time resolutions

FEASIBILITY STUDY OF PRESSURE PULSING PIPELINE UNPLUGGING TECHNOLOGIES FOR HANFORD

Energy Technology Data Exchange (ETDEWEB)

Servin, M. A. [Washington River Protection Solutions, LLC, Richland, WA (United States); Garfield, J. S. [AEM Consulting, LLC (United States); Golcar, G. R. [AEM Consulting, LLC (United States)

2012-12-20

The ability to unplug key waste transfer routes is generally essential for successful tank farms operations. All transfer lines run the risk of plugging but the cross site transfer line poses increased risk due to its longer length. The loss of a transfer route needed to support the waste feed delivery mission impacts the cost and schedule of the Hanford clean up mission. This report addresses the engineering feasibility for two pressure pulse technologies, which are similar in concept, for pipeline unplugging.

Feasibility Study Of Pressure Pulsing Pipeline Unplugging Technologies For Hanford

International Nuclear Information System (INIS)

Servin, M. A.; Garfield, J. S.; Golcar, G. R.

2012-01-01

The ability to unplug key waste transfer routes is generally essential for successful tank farms operations. All transfer lines run the risk of plugging but the cross site transfer line poses increased risk due to its longer length. The loss of a transfer route needed to support the waste feed delivery mission impacts the cost and schedule of the Hanford clean up mission. This report addresses the engineering feasibility for two pressure pulse technologies, which are similar in concept, for pipeline unplugging

Large amplitude solitary waves in a multicomponent plasma with negative ions

International Nuclear Information System (INIS)

Nakamura, Y.; Tsukabayashi, I.; Ludwig, G.O.; Ferreira, J.L.

1987-09-01

When the concentration of negative ions is larger than a critical value, a small compressive pulse evolves into a subsonic wave train and a large pulse develops into a solitary wave. The threshold amplitude and velocity of the solitary waves are measured and compared with predictions using the pseudopotential method. (author) [pt

An in vitro quantification of pressures exerted by earlobe pulse oximeter probes following reports of device-related pressure ulcers in ICU patients .

Science.gov (United States)

Goodell, Teresa T

2012-11-01

The earlobe often is used to monitor perfusion when pulse oximeter signal quality is impaired in the fingers and toes. Prompted by intermittent occurrences of roughly circular earlobe pressure ulcers among patients in intensive care units, a convenience sample of seven calibrated pulse oximeter probes was used to quantify earlobe pressure exerted by these devices in vitro. All were tested twice with an electronic load cell, a strain gauge with a transducer that transforms the measured force into a readable numerical signal. The probe was clipped to the load cell just as it is clipped to the earlobe in the clinical setting. The probes exerted an average of 0.24 lb (SD 0.6) of force over an area of 0.3 square inches, equal to an average of 20.7 mm Hg (SD 0.6) pressure on tissue. This value exceeds some empirically derived values of capillary perfusion pressure. The occurrence of device-related pressure ulcers, as well pressure ulcers on the ears, has been documented, but little is known about device-related earlobe pressure ulcers or the actual pressure exerted by these devices. Additional in vitro studies are needed to quantify the pressures exerted by these and other probes, and future prevalence and incidence studies should include more detailed pressure ulcer location and device use documentation. Until more is known about the possible role of these devices in the development of pressure ulcers, clinicians should be cognizant of their potential for causing pressure ulcers, particularly in patients whose conditions can compromise skin integrity.

Nonresonant Multiple-Pulse Control of Molecular Motions in Liquid

Directory of Open Access Journals (Sweden)

Nikiforov V.G.

2015-01-01

Full Text Available We propose the implementation of the multiple-pulse excitation for manipulation of the molecular contributions to the optically-heterodyne-detected optical-Kerr-effect. The key parameters controlling the specificity of the multiple-pulse excitation scenarios are the pulses durations, the delays between pulses, the relation between the pump pulses amplitudes and the pulses polarizations. We model the high-order optical responses and consider some principles of the scenarios construction. We show that it is possible to adjust the excitation scenario in such a way that the some responses can be removed from detected signal along with the enhancement of the interested response amplitude. The theoretical analysis and first experimental data reveal that the multiple-pulse excitation technique can be useful for the selective spectroscopy of the molecular vibrations and rotations in liquid.

Bystander Effect Induced by Electroporation is Possibly Mediated by Microvesicles and Dependent on Pulse Amplitude, Repetition Frequency and Cell Type.

Science.gov (United States)

Prevc, Ajda; Bedina Zavec, Apolonija; Cemazar, Maja; Kloboves-Prevodnik, Veronika; Stimac, Monika; Todorovic, Vesna; Strojan, Primoz; Sersa, Gregor

2016-10-01

Bystander effect, a known phenomenon in radiation biology, where irradiated cells release signals which cause damage to nearby, unirradiated cells, has not been explored in electroporated cells yet. Therefore, our aim was to determine whether bystander effect is present in electroporated melanoma cells in vitro, by determining viability of non-electroporated cells exposed to medium from electroporated cells and by the release of microvesicles as potential indicators of the bystander effect. Here, we demonstrated that electroporation of cells induces bystander effect: Cells exposed to electric pulses mediated their damage to the non-electroporated cells, thus decreasing cell viability. We have shown that shedding microvesicles may be one of the ways used by the cells to mediate the death signals to the neighboring cells. The murine melanoma B16F1 cell line was found to be more electrosensitive and thus more prone to bystander effect than the canine melanoma CMeC-1 cell line. In B16F1 cell line, bystander effect was present above the level of electropermeabilization of the cells, with the threshold at 800 V/cm. Furthermore, with increasing electric field intensities and the number of pulses, the bystander effect also increased. In conclusion, electroporation can induce bystander effect which may be mediated by microvesicles, and depends on pulse amplitude, repetition frequency and cell type.

High Frequency Amplitude Detector for GMI Magnetic Sensors

Directory of Open Access Journals (Sweden)

Aktham Asfour

2014-12-01

Full Text Available A new concept of a high-frequency amplitude detector and demodulator for Giant-Magneto-Impedance (GMI sensors is presented. This concept combines a half wave rectifier, with outstanding capabilities and high speed, and a feedback approach that ensures the amplitude detection with easily adjustable gain. The developed detector is capable of measuring high-frequency and very low amplitude signals without the use of diode-based active rectifiers or analog multipliers. The performances of this detector are addressed throughout the paper. The full circuitry of the design is given, together with a comprehensive theoretical study of the concept and experimental validation. The detector has been used for the amplitude measurement of both single frequency and pulsed signals and for the demodulation of amplitude-modulated signals. It has also been successfully integrated in a GMI sensor prototype. Magnetic field and electrical current measurements in open- and closed-loop of this sensor have also been conducted.

Fast differential pulse discriminator-counter

International Nuclear Information System (INIS)

Shelevoj, K.D.

1985-01-01

The flowsheet of a differential pulse discriminator counter is described; the result of discrimination here is independent from the shape of the input pulse. Rate of the analysis of input pulses with minimum amplitude up to 0.3 mV coming out from the photomultiplier makes up 220 MHz. The flowsheet of the discriminator used in the system of photon counting for atmosphere probing is presented

Consumer acceptance of high-pressure processing and pulsed-electric-field

DEFF Research Database (Denmark)

Olsen, Nina Veflen; Grunert, Klaus G.; Sonne, Anne-Mette

2010-01-01

New products and new processing techniques are continuously developed in the food industry. While food scientists may focus on the technical novelty and applaud the progress of science, consumers are often conservative and sceptical towards changes. The advantages that a new processing technology...... has to offer, do not necessarily guarantee the success of a product in the market place. Consumer acceptance depends on whether consumers perceive that there are specific benefits associated with the product. This review focuses specifically on how high-pressure processing (HPP) and pulsed...

Modulated pumping in Cs with picosecond pulse trains

International Nuclear Information System (INIS)

Lehmitz, H.; Harde, H.; Kattau, W.

1986-01-01

Two different experimental arrangements were used for periodic excitation detection of coherence. Cs vapor in a gas cell was resonantly excited on the D 2 line by a train of ultrashort light pulses of circular polarization. To reduce transit-time broadening, additional buffer gas was contained in the cell and the light beam from a laser was expanded to a cross section of about 1.5 cm 2 . The resulting atomic coherence amplitude which was due to the periodic excitation of atoms could then be measured by different means. The experimental set-up is shown which takes advantage of the fact that atomic coherence gives rise to an oscillating optical anisotropy in the sample. The atomic splitting is measured by the 9th harmonic of the injection laser pulse rate with a width of less than 50 Hz. The experiments demonstrate the ultrahigh frequency resolution is possible with optical pulse train interference spectroscopy which allows one to sensitively detect small pressure shifts in the hyperfine frequency caused by buffer gases in the gas cell

Charged particle interaction with a chirped electromagnetic pulse

NARCIS (Netherlands)

Khachatryan, A.G.; Boller, Klaus J.; van Goor, F.A.

2003-01-01

It is found that a charged particle can get a net energy gain from the interaction with an electromagnetic chirped pulse. Theoretically, the energy gain increases with the pulse amplitude and with the relative frequency variation in the pulse.

The effects of balneotherapy on blood pressure and pulse in osteoarthritis patients with hypertension.

Science.gov (United States)

Umay, Ebru; Tezelli, Mustafa Kemal; Meshur, Mehmet; Umay, Serkan

2013-01-01

Balneotherapy is a treatment modality that uses the physical and chemical effects of water, including thermomineral, acratothermal, and acratopegal waters. Although balneotherapy is an ancient treatment method that has a limited use within current treatment modalities, it is still widely popular with the public. Studies usually have reported that balneotherapy is associated with an increased risk of complications, especially in patients with hypertension (HT). The research team intended this study to evaluate the effects of balneotherapy on peripheral, arterial blood pressure and pulse in osteoarthritis (OA) patients with HT, compared to normotensive patients. For the current study, the research team examined the medical records of 5814 patients who were hospitalized and treated for OA at the team's institution between 2008 and 2010. This examination involved a review of the evaluation form that a nurse had obtained when those patients entered the hospital. This study was done at a balneotherapy hospital. Participants were 2090 individuals, including 1036 (49.6%) with primary (essential) HT and 1054 (50.4%) normotensives, with OA of the lumbosacral region, knee, hand, and foot. All participants received balneotherapy at the same time every day (10:00-10:30 AM) for 20 min/d, 5 d/wk, for a total duration of 15 d. Following balneotherapy, all participants performed an exercise program consisting of range of motion (ROM) and stretching exercises. Measurements of pulse and systolic and diastolic blood pressures were recorded before treatment and after 15 sessions of balneotherapy. Within-group and between-group comparisons of results of pulse and systolic and diastolic blood pressure measurements were performed. The study found a significant reduction after treatment in systolic and diastolic blood pressures in both normotensive and HT participants. Moreover, the reduction in diastolic blood pressure was noted to be greater in the HT group (P = .046). Balneotherapy may

Numerical simulation of atmospheric-pressure helium discharge driven by combined radio frequency and trapezoidal pulse sources

International Nuclear Information System (INIS)

Wang Qi; Sun Jizhong; Zhang Jianhong; Ding Zhenfeng; Wang Dezhen

2010-01-01

Atmospheric-pressure capacitive discharges driven by combined radio frequency (rf) and trapezoidal pulse sources are investigated using a one-dimensional self-consistent fluid model. The results show that the plasma intensity in the rf discharge can be enhanced drastically when a low duty ratio short pulse source is additionally applied. The mechanism for the increase in the plasma density can be attributed to a strong localized electric field induced by the applied short pulse; the strong electric field generates a great number of high energy electrons and chemically active particles, which subsequently generate more electrons and ions. The rf capacitive discharges with the aid of externally applied short pulses can achieve a high plasma density with better power efficiency.

Vasodilation increases pulse pressure variation, mimicking hypovolemic status in rabbits

Directory of Open Access Journals (Sweden)

Glauco A Westphal

2010-01-01

Full Text Available OBJECTIVE: To test the hypothesis that pulse pressure respiratory variation (PPV amplification, observed in hypovolemia, can also be observed during sodium nitroprusside (SNP-induced vasodilation. INTRODUCTION: PPV is largely used for early identification of cardiac responsiveness, especially when hypovolemia is suspected. PPV results from respiratory variation in transpulmonary blood flow and reflects the left ventricular preload variations during respiratory cycles. Any factor that decreases left ventricular preload can be associated with PPV amplification, as seen in hypovolemia. METHODS: Ten anesthetized and mechanically ventilated rabbits underwent progressive hypotension by either controlled hemorrhage (Group 1 or intravenous SNP infusion (Group 2. Animals in Group 1 (n = 5 had graded hemorrhage induced at 10% steps until 50% of the total volume was bled. Mean arterial pressure (MAP steps were registered and assumed as pressure targets to be reached in Group 2. Group 2 (n = 5 was subjected to a progressive SNP infusion to reach similar pressure targets as those defined in Group 1. Heart rate (HR, systolic pressure variation (SPV and PPV were measured at each MAP step, and the values were compared between the groups. RESULTS: SPV and PPV were similar between the experimental models in all steps (p > 0.16. SPV increased earlier in Group 2. CONCLUSION: Both pharmacologic vasodilation and graded hemorrhage induced PPV amplification similar to that observed in hypovolemia, reinforcing the idea that amplified arterial pressure variation does not necessarily represent hypovolemic status but rather potential cardiovascular responsiveness to fluid infusion.

Charge-storage techniques for pulse-height analysis; Techniques de stockage electrostatique pour l'analyse en amplitude d'impulsion; Metod nakopleniya zaryada dlya amplitudnogo analiza impul'sov; Tecnicas de almacenamiento de cargas para analisis de amplitud de impulsos

Energy Technology Data Exchange (ETDEWEB)

Costrell, L; Brueckmann, R E [National Bureau of Standards, Washington, DC (United States)

1962-04-15

The low-duty cycles of many pulsed accelerators make high pulse rates necessary within the bursts in order to accumulate adequate data in a reasonable time. Not only do economic factors, as influenced by expensive machine time, dictate the use of high pulse rates, but purely technical considerations often make experiments unfeasible unless the pulses per burst are so numerous as to exclude the use of conventional pulse-height analysers. For these reasons much effort has been devoted to the development of high-speed pulse-height analysers for use with pulsed accelerators. Much of this work has been directed toward producing what we term a ''charge-storage analyser'' based on work conducted at the National Bureau of Standards. We have developed a charge-storage analyser that operates with the NBS 180-MeV synchrotron on a nuclear-absorption experiment for which the obstacles would otherwise be formidable. The analyser uses temporary electrostatic storage for the accumulation of pulse-height data during the machine bursts. During the dead intervals between bursts the contents of the temporary storage are analysed and transferred into a conventional magnetic core memory. The use of this technique for nanosecond pulses is discussed and data is presented to show its feasibility. (author) [French] Comme la partie du cycle de travail effectivement utilisee dans un grand nombre d'accelerateurs nucleaires puises est tres faible, il faut employer des frequences de repetition elevees pendant les bouffees, si l'on veut accumuler suffisamment de resultats en un temps raisonnable. Non seulement les facteurs economiques - influences par l'importance du temps de fonctionnement d'une machine couteuse - imposent des frequences de repetition elevees mais les experiences sont bien souvent irrealisables pour des raisons purement techniques, a moins que le nombre d'impulsions utilisees ne permettent de se passer d'analyseurs classiques des amplitudes d'impulsion. C'est pourquoi on a

A Novel Subnanosecond Monocycle Pulse Generator for UWB Radar Applications

Directory of Open Access Journals (Sweden)

Xinfan Xia

2014-01-01

Full Text Available A novel ultra-wideband (UWB monocycle pulse generator with good performance is designed and demonstrated in this paper. It contains a power supply circuit, a pulse drive circuit, a unique pulse forming circuit, and a novel monopolar-to-monocycle pulse transition circuit. The drive circuit employs wideband bipolar junction transistors (BJTs and linear power amplifier transistor to produce a high amplitude drive pulse, and the pulse forming circuit uses the transition characteristics of step recovery diode (SRD effectively to produce a negative narrow pulse. At last, the monocycle pulse forming circuit utilizes a novel inductance L short-circuited stub to generate the monocycle pulse directly. Measurement results show that the waveform of the generated monocycle pulses is over 76 V in peak-to-peak amplitude and 3.2 ns in pulse full-width. These characteristics of the monocycle pulse are advantageous for obtaining long detection range and high resolution, when it is applied to ultra-wideband radar applications.

Development of Ultrasonic Pulse Compression Using Golay Codes

International Nuclear Information System (INIS)

Kim, Young H.; Kim, Young Gil; Jeong, Peter

1994-01-01

Conventional ultrasonic flaw detection system uses a large amplitude narrow pulse to excite a transducer. However, these systems are limited in pulse energy. An excessively large amplitude causes a dielectric breakage of the transducer, and an excessively long pulse causes decrease of the resolution. Using the pulse compression, a long pulse of pseudorandom signal can be used without sacrificing resolution by signal correlation. In the present work, the pulse compression technique was implemented into an ultrasonic system. Golay code was used as a pseudorandom signal in this system, since pair sum of autocorrelations has no sidelobe. The equivalent input pulse of the Golay code was derived to analyze the pulse compression system. Throughout the experiment, the pulse compression technique has demonstrated for its improved SNR(signal to noise ratio) by reducing the system's white noise. And the experimental data also indicated that the SNR enhancement was proportional to the square root of the code length used. The technique seems to perform particularly well with highly energy-absorbent materials such as polymers, plastics and rubbers

Ultrarelativistic electromagnetic pulses in plasmas

Science.gov (United States)

Ashour-Abdalla, M.; Leboeuf, J. N.; Tajima, T.; Dawson, J. M.; Kennel, C. F.

1981-01-01

The physical processes of a linearly polarized electromagnetic pulse of highly relativistic amplitude in an underdense plasma accelerating particles to very high energies are studied through computer simulation. An electron-positron plasma is considered first. The maximum momenta achieved scale as the square of the wave amplitude. This acceleration stops when the bulk of the wave energy is converted to particle energy. The pulse leaves behind as a wake a vacuum region whose length scales as the amplitude of the wave. The results can be explained in terms of a snow plow or piston-like action of the radiation on the plasma. When a mass ratio other than unity is chosen and electrostatic effects begin to play a role, first the ion energy increases faster than the electron energy and then the electron energy catches up later, eventually reaching the same value.

Pulsed neutron sources at KAON

International Nuclear Information System (INIS)

Thorson, I.M.; Egelstaff, P.A.; Craddock, M.K.

1991-01-01

The proposed KAON Factory facility at TRIUMF consists of a number of synchrotrons and storage rings which offer proton beams of energies between 0.45 and 30 GeV with varying pulse amplitudes, widths and repetition rates. Various possibilities for feeding these beams to a pulsed neutron facility and their potential for future development are examined. The incremental cost of such a pulsed neutron facility is estimated approximately. (author)

Neurokinin B receptor antagonism decreases luteinising hormone pulse frequency and amplitude and delays puberty onset in the female rat.

Science.gov (United States)

Li, S Y; Li, X F; Hu, M H; Shao, B; Poston, L; Lightman, S L; O'Byrne, K T

2014-08-01

The neural mechanisms controlling puberty onset remain enigmatic. Humans with loss of function mutations in TAC3 or TACR3, the genes encoding neurokinin B (NKB) or its receptor, neurokinin-3 receptor (NK3R), respectively, present with severe congenital gonadotrophin deficiency and pubertal failure. Animal studies have shown ambiguous actions of NKB-NK3R signalling with respect to controlling puberty onset. The present study aimed to determine the role of endogenous NKB-NK3R signalling in the control of pulsatile luteinising hormone (LH) secretion and the timing of puberty onset, and also whether precocious pubertal onset as a result of an obesogenic diet is similarly regulated by this neuropeptide system. Prepubertal female rats, chronically implanted with i.c.v. cannulae, were administered SB222200, a NK3R antagonist, or artificial cerebrospinal fluid via an osmotic mini-pump for 14 days. SB222200 significantly delayed the onset of vaginal opening and first oestrus (as markers of puberty) compared to controls in both normal and high-fat diet fed animals. Additionally, serial blood sampling, via chronic indwelling cardiac catheters, revealed that the increase in LH pulse frequency was delayed and that the LH pulse amplitude was reduced in response to NK3R antagonism, regardless of dietary status. These data suggest that endogenous NKB-NK3R signalling plays a role in controlling the timing of puberty and the associated acceleration of gonadotrophin-releasing hormone pulse generator frequency in the female rat. © 2014 British Society for Neuroendocrinology.

A Novel Interpretation for Arterial Pulse Pressure Amplification in Health and Disease

Directory of Open Access Journals (Sweden)

Manuel R. Alfonso

2018-01-01

Full Text Available Arterial pressure waves have been described in one dimension using several approaches, such as lumped (Windkessel or distributed (using Navier-Stokes equations models. An alternative approach consists of modeling blood pressure waves using a Korteweg-de Vries (KdV equation and representing pressure waves as combinations of solitons. This model captures many key features of wave propagation in the systemic network and, in particular, pulse pressure amplification (PPA, which is a mechanical biomarker of cardiovascular risk. The main objective of this work is to compare the propagation dynamics described by a KdV equation in a human-like arterial tree using acquired pressure waves. Furthermore, we analyzed the ability of our model to reproduce induced elastic changes in PPA due to different pathological conditions. To this end, numerical simulations were performed using acquired central pressure signals from different subject groups (young, adults, and hypertensive as input and then comparing the output of the model with measured radial artery pressure waveforms. Pathological conditions were modeled as changes in arterial elasticity (E. Numerical results showed that the model was able to propagate acquired pressure waveforms and to reproduce PPA variations as a consequence of elastic changes. Calculated elasticity for each group was in accordance with the existing literature.

Pulse Width Affects Scalp Sensation of Transcranial Magnetic Stimulation.

Science.gov (United States)

Peterchev, Angel V; Luber, Bruce; Westin, Gregory G; Lisanby, Sarah H

Scalp sensation and pain comprise the most common side effect of transcranial magnetic stimulation (TMS), which can reduce tolerability and complicate experimental blinding. We explored whether changing the width of single TMS pulses affects the quality and tolerability of the resultant somatic sensation. Using a controllable pulse parameter TMS device with a figure-8 coil, single monophasic magnetic pulses inducing electric field with initial phase width of 30, 60, and 120 µs were delivered in 23 healthy volunteers. Resting motor threshold of the right first dorsal interosseus was determined for each pulse width, as reported previously. Subsequently, pulses were delivered over the left dorsolateral prefrontal cortex at each of the three pulse widths at two amplitudes (100% and 120% of the pulse-width-specific motor threshold), with 20 repetitions per condition delivered in random order. After each pulse, subjects rated 0-to-10 visual analog scales for Discomfort, Sharpness, and Strength of the sensation. Briefer TMS pulses with amplitude normalized to the motor threshold were perceived as slightly more uncomfortable than longer pulses (with an average 0.89 point increase on the Discomfort scale for pulse width of 30 µs compared to 120 µs). The sensation of the briefer pulses was felt to be substantially sharper (2.95 points increase for 30 µs compared to 120 µs pulse width), but not stronger than longer pulses. As expected, higher amplitude pulses increased the perceived discomfort and strength, and, to a lesser degree the perceived sharpness. Our findings contradict a previously published hypothesis that briefer TMS pulses are more tolerable. We discovered that the opposite is true, which merits further study as a means of enhancing tolerability in the context of repetitive TMS. Copyright © 2016 Elsevier Inc. All rights reserved.

Dynamics of laser-induced channel formation in water and influence of pulse duration on the ablation of biotissue under water with pulsed erbium-laser radiation

Science.gov (United States)

Ith, M.; Pratisto, H.; Altermatt, H. J.; Frenz, M.; Weber, H. P.

1994-12-01

The ability to use fiber-delivered erbium-laser radiation for non-contact arthroscopic meniscectomy in a liquid environment was studied. The laser radiation is transmitted through a water-vapor channel created by the leading part of the laser pulse. The dynamics of the channel formation around a submerged fiber tip was investigated with time-resolved flash photography. Strong pressure transients with amplitudes up to a few hundreds of bars measured with a needle hydrophone were found to accompany the channel formation process. Additional pressure transients in the range of kbars were observed after the laser pulse associated with the collapse of the vapor channel. Transmission measurements revealed that the duration the laser-induced channel stays open, and therefore the energy transmittable through it, is substantially determined by the laser pulse duration. The optimum pulse duration was found to be in the range between 250 and 350 µS. This was confirmed by histological evaluations of the laser incisions in meniscus: Increasing the pulse duration from 300 to 800 µs leads to a decrease in the crater depth from 1600 to 300 µm. A comparison of the histological examination after laser treatment through air and through water gave information on the influence of the vapor channel on the ablation efficiency, the cutting quality and the induced thermal damage in the adjacent tissue. The study shows that the erbium laser combined with an adequate fiber delivery system represents an effective surgical instrument liable to become increasingly accepted in orthopedic surgery.

Signal-Pressure Curves of Cascaded Four-Wave Mixing in Gas-Filled Capillary by fs Pulses

International Nuclear Information System (INIS)

Chen Baozhen; Huang Zuqia

2005-01-01

The theoretical framework for the cascaded four waves mixing (CFWM) in gas-filled capillary by fs pulses is constructed. Based on the theoretical framework, the signal-pressure curves (SPC) of the CFWM in gas-filled capillary by fs pulses are calculated. With a comparison between the theoretical and experimental SPC we have discussed the influence of the walk-off and phase modulation on the SPC. At the same time, we have discussed the possible origin of the first three peaks of the SPC.

The random signal generator of imitated nuclear radiation pulse

International Nuclear Information System (INIS)

Li Dongcang; Yang Lei; Yuan Shulin; Yang Yinghui; Zang Fujia

2007-01-01

Based in pseudo-random uniformity number, it produces random numbers of Gaussian distribution and exponential distribution by arithmetic. The hardware is the single-chip microcomputer of 89C51. Program language makes use of Keil C. The output pulse amplitude is Gaussian distribution, exponential distribution or uniformity distribution. Likewise, it has two mode or upwards two. The time alternation of output pulse is both periodic and exponential distribution. The generator has achieved output control of multi-mode distribution, imitated random characteristic of nuclear pulse in amplitude and in time. (authors)

Relations between diabetes, blood pressure and aortic pulse wave velocity in haemodialysis patients

DEFF Research Database (Denmark)

Peters, Christian Daugaard; Kjærgaard, Krista Dybtved; Dzeko, Mirela

(HD) and 32 HD patients with DM (HD+DM). The SphygmoCor system was used for estimation of PWV. HD-duration, age, gender and BP medication were similar in the two groups. Mean DM-duration was 23±11 years and 25(78%) had type 2 DM. HD+DM had higher BMI (26±5 vs. 29±5 kg/m2, p=0.02), systolic BP (142......Diabetes (DM) is common in haemodialysis (HD) patients and affects both blood pressure (BP) and arterial stiffness. Carotid femoral pulse wave velocity (PWV) reflects the stiffness of the aorta and is regarded as a strong risk factor for cardiovascular (CV) mortality in HD patients. However, PWV......±20 vs. 152±21 mmHg, p=0.02) and pulse pressure (65±17 vs. 80±18 mmHg, p2.5 in HD and 12.3±3.1 m/s in HD+DM. The mean PWV difference HD vs. HD+DM was 3.1(1.9-4.3)m/s, p

Computer code for the analysis of destructive pressure generation process during a fuel failure accident, PULSE-2

International Nuclear Information System (INIS)

Fujishiro, Toshio

1978-03-01

The computer code PULSE-2 has been developed for the analysis of pressure pulse generation process when hot fuel particles come into contact with the coolant in a fuel rod failure accident. In the program, it is assumed that hot fuel fragments mix with the coolant instantly and homogeneously in the failure region. Then, the rapid vaporization of the coolant and transient pressure rise in failure region, and the movement of ejected coolant slugs are calculated. The effect of a fuel-particle size distribution is taken into consideration. Heat conduction in the fuel particles and heat transfer at fuel-coolant interface are calculated. Temperature, pressure and void fraction in the mixed region are calculated from the average enthalpy. With physical property subroutines for liquid sodium and water, the model is usable for both LMFBR and LWR conditions. (auth.)

Pulse Pressure, Instead of Brachium-Ankle Pulse Wave Velocity, is Associated with Reduced Kidney Function in a Chinese Han Population.

Science.gov (United States)

Jia, Linpei; Zhang, Weiguang; Ma, Jie; Chen, Xizhao; Chen, Lei; Li, Zuoxiang; Cai, Guangyan; Huang, Jing; Zhang, Jinping; Bai, Xiaojuan; Feng, Zhe; Sun, Xuefeng; Chen, Xiangmei

2017-01-01

In this study, we aim to investigate the association between renal function and arterial stiffness in a Chinese Han population, and further to discuss the effects of smoking on renal function. We collected the data of the brachium-ankle pulse wave velocity (baPWV), blood pressure, blood chemistry and smoking status. Then, the multiple linear regression was done to explore the relationship between estimated glomerular filtration (eGFR) and baPWV. Further, the parameters were compared among the four groups divided according to the quartiles of baPWV. Finally, the baPWV, eGFR and albuminuria values were compared between smokers and non-smokers. baPWV is associated with eGFR in the correlation analysis and univariate linear regression model. After adjustment, the pulse pressure (PP) instead of baPWV showed a significant association with eGFR. Nevertheless, the eGFR values differed among the four baPWV groups; the baPWV values were significantly higher in the subjects at the CKD (eGFRfunction. Smokers have worse arterial stiffness and worse renal function. © 2017 The Author(s)Published by S. Karger AG, Basel.

Modeling seismic stimulation: Enhanced non-aqueous fluid extraction from saturated porous media under pore-pressure pulsing at low frequencies

Science.gov (United States)

Lo, Wei-Cheng; Sposito, Garrison; Huang, Yu-Han

2012-03-01

Seismic stimulation, the application of low-frequency stress-pulsing to the boundary of a porous medium containing water and a non-aqueous fluid to enhance the removal of the latter, shows great promise for both contaminated groundwater remediation and enhanced oil recovery, but theory to elucidate the underlying mechanisms lag significantly behind the progress achieved in experimental research. We address this conceptual lacuna by formulating a boundary-value problem to describe pore-pressure pulsing at seismic frequencies that is based on the continuum theory of poroelasticity for an elastic porous medium permeated by two immiscible fluids. An exact analytical solution is presented that is applied numerically using elasticity parameters and hydraulic data relevant to recent proof-of-principle laboratory experiments investigating the stimulation-induced mobilization of trichloroethene (TCE) in water flowing through a compressed sand core. The numerical results indicated that significant stimulation-induced increases of the TCE concentration in effluent can be expected from pore-pressure pulsing in the frequency range of 25-100 Hz, which is in good agreement with what was observed in the laboratory experiments. Sensitivity analysis of our numerical results revealed that the TCE concentration in the effluent increases with the porous medium framework compressibility and the pulsing pressure. Increasing compressibility also leads to an optimal stimulation response at lower frequencies, whereas changing the pulsing pressure does not affect the optimal stimulation frequency. Within the context of our model, the dominant physical cause for enhancement of non-aqueous fluid mobility by seismic stimulation is the dilatory motion of the porous medium in which the solid and fluid phases undergo opposite displacements, resulting in stress-induced changes of the pore volume.

The role of pulse shape in motor cortex transcranial magnetic stimulation using full-sine stimuli

DEFF Research Database (Denmark)

Delvendahl, Igor; Gattinger, Norbert; Berger, Thomas

2014-01-01

A full-sine (biphasic) pulse waveform is most commonly used for repetitive transcranial magnetic stimulation (TMS), but little is known about how variations in duration or amplitude of distinct pulse segments influence the effectiveness of a single TMS pulse to elicit a corticomotor response. Using......) compared monophasic, half-sine, and full-sine pulses, (ii) applied two-segment pulses consisting of two identical half-sines, and (iii) manipulated amplitude, duration, and current direction of the first or second full-sine pulse half-segments. RMT was significantly higher using half-sine or monophasic...... in considerably higher RMT, whereas varying the amplitude of the half-segment inducing anterior-posterior current had a smaller effect. These findings provide direct experimental evidence that the pulse segment inducing a posterior-anterior directed current in M1 contributes most to corticospinal pathway...

Coherent pulse interrogation system for fiber Bragg grating sensing of strain and pressure in dynamic extremes of materials.

Science.gov (United States)

Rodriguez, George; Jaime, Marcelo; Balakirev, Fedor; Mielke, Chuck H; Azad, Abul; Marshall, Bruce; La Lone, Brandon M; Henson, Bryan; Smilowitz, Laura

2015-06-01

A 100 MHz fiber Bragg grating (FBG) interrogation system is described and applied to strain and pressure sensing. The approach relies on coherent pulse illumination of the FBG sensor with a broadband short pulse from a femtosecond modelocked erbium fiber laser. After interrogation of the FBG sensor, a long multi-kilometer run of single mode fiber is used for chromatic dispersion to temporally stretch the spectral components of the reflected pulse from the FBG sensor. Dynamic strain or pressure induced spectral shifts in the FBG sensor are detected as a pulsed time domain waveform shift after encoding by the chromatic dispersive line. Signals are recorded using a single 35 GHz photodetector and a 50 G Samples per second, 25 GHz bandwidth, digitizing oscilloscope. Application of this approach to high-speed strain sensing in magnetic materials in pulsed magnetic fields to ~150 T is demonstrated. The FBG wavelength shifts are used to study magnetic field driven magnetostriction effects in LaCoO3. A sub-microsecond temporal shift in the FBG sensor wavelength attached to the sample under first order phase change appears as a fractional length change (strain: ΔL/L-4) in the material. A second application used FBG sensing of pressure dynamics to nearly 2 GPa in the thermal ignition of the high explosive PBX-9501 is also demonstrated. Both applications demonstrate the use of this FBG interrogation system in dynamical extreme conditions that would otherwise not be possible using traditional FBG interrogation approaches that are deemed too slow to resolve such events.

Design of a high-pressure single pulse shock tube for chemical kinetic investigations

International Nuclear Information System (INIS)

Tranter, R. S.; Brezinsky, K.; Fulle, D.

2001-01-01

A single pulse shock tube has been designed and constructed in order to achieve extremely high pressures and temperatures to facilitate gas-phase chemical kinetic experiments. Postshock pressures of greater than 1000 atmospheres have been obtained. Temperatures greater than 1400 K have been achieved and, in principle, temperatures greater than 2000 K are easily attainable. These high temperatures and pressures permit the investigation of hydrocarbon species pyrolysis and oxidation reactions. Since these reactions occur on the time scale of 0.5--2 ms the shock tube has been constructed with an adjustable length driven section that permits variation of reaction viewing times. For any given reaction viewing time, samples can be withdrawn through a specially constructed automated sampling apparatus for subsequent species analysis with gas chromatography and mass spectrometry. The details of the design and construction that have permitted the successful generation of very high-pressure shocks in this unique apparatus are described. Additional information is provided concerning the diaphragms used in the high-pressure shock tube

Effects of Roselle on arterial pulse pressure and left ventricular hypertrophy in hypertensive patients.

Science.gov (United States)

Al-Shafei, Ahmad I; El-Gendy, Ola A

2013-12-01

To characterize the effects of regular Roselle ingestion on blood pressure and left ventricular hypertrophy (LVH) in patients with established moderate essential hypertension. This non-randomized quasi-experimental study was conducted in Kafr El-Shaikh, Egypt, for 8 weeks, from September 2012 to November 2012. The effects of a 4-week period of regular Roselle ingestion followed by a 4-week recovery period on systolic blood pressure (SBP), diastolic blood pressure (DBP), pulse pressure (PP), and heart rates (HR) was studied in 2 equal, gender- and age-matched groups (n=50 each; average age - 50+/-5 years) of normotensive subjects, and patients with moderate essential hypertension. Electrocardiographic assessments of LVH were also made prior to, and at the end of both treatment and recovery periods. Pulse pressure (PP) significantly fell from baseline values by 10.9% (normotensive group [NG]), 21.2% (hypertensive group [HG]); SBP by 10% (NG), 19.6% (HG); DBP by 9.5% (NG), 18.7% (HG), and HR by 14.6% (NG), 17.1% (HG) by the end of week 4 of treatment. Following treatment cessation, SBP, DBP, PP, and HR returned to pretreatment levels over 4 weeks. Before intervention, none of the normotensive subjects, but 14 hypertensive patients showed LVH. However, Roselle treatment was associated with regression of LVH in 10 patients with only 4 patients showing LVH after 4 weeks of treatment. This became 10 patients 4 weeks after ceasing treatment. These findings empirically suggest favorable cardiovascular effects of Roselle in patients with established moderate essential hypertension.

Time-amplitude converter; Convertisseur temps-amplitude

Energy Technology Data Exchange (ETDEWEB)

Banner, M [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires

1961-07-01

It is normal in high energy physics to measure the time of flight of a particle in order to determine its mass. This can be done by the method which consists in transforming the time measurement into an analysis of amplitude, which is easier; a time-amplitude converter has therefore been built for this purpose. The apparatus here described uses a double grid control tube 6 BN 6 whose resolution time, as measured with a pulse generator, is 5 x 10{sup -11} s. The analysis of the response of a particle counter, made up of a scintillator and a photomultiplier, indicates that a time of resolution of 5 x 10{sup -10} s. can be obtained. A time of this order of magnitude is obtained experimentally with the converter. This converter has been used in the study of the time of flight of particles in a secondary beam of the accelerator Saturne. It has thus been possible to measure the energy spectrum of {pi}-mesons, of protons, and of deutons emitted from a polyethylene target bombarded by 1,4 and 2 GeV protons. (author) [French] Pour determiner la masse d'une particule, il est courant, en physique des hautes energies, de mesurer le temps de vol de cette particule. Cela peut etre fait par la methode qui consiste a transformer la mesure d'un temps en une analyse d'amplitude, plus aisee; aussi a-t-on, a cet effet, cree un convertisseur temps-amplitude. L'appareillage decrit dans cet article utilise un tube a double grille de commande 6 BN 6 dont le temps de resolution mesure avec un generateur d'impulsion est de 5.10{sup -11} s. L'analyse de la reponse d'un compteur de particules, constitue par un scintillateur et un photomultiplicateur, indique qu'un temps de resolution de 5.10{sup -10} s peut etre obtenu. Un temps de cet ordre est atteint experimentalement avec le convertisseur. Ce convertisseur a servi a l'etude du temps de vol des particules dans un faisceau secondaire de l'accelerateur Saturne. On a mesure ainsi le spectre d'energie des mesons {pi}, des protons, des deutons

Analysis of physiological (pao/sub 2/, pulse and blood pressure) changes during modified ect under general anaesthesia

International Nuclear Information System (INIS)

Shah, M.; Shah, H.A.; Shah, F.S.

2015-01-01

To study the changes in physiological parameters i e PAO2, pulse and blood pressure changes during ECT under GA. Study Design: Quasi-experimental study. Place and Duration of Study: Department of Psychiatry and Department of Anaesthesiology, Combined Military Hospital Abbottabad from Sep 2009 to Feb 2010. Patients and Methods: A total of 50 patients with depression were given four separate ECT sessions each. All patients were anaesthetized using propofol 180-200 mg I/V and suxamethonium 50 mg i e 0.75-1 mg per kg I/V without atropine. They were stratified according to physiological changes including PAO2, pulse and blood pressure at 1, 2 and 5 min after ECT. Oxygen saturation was measured using a pulse oximeter, which measures saturations in the range of 65-100%. Results: Age range was 19-65 years; mean 46 years (SD+-13). Mean diastolic BP before ECT was 84.72 that decreased post ECT ie 78.02 and 77.46 and 74.44 at interval of 1, 2 and 5 minute respectively. Post-ECT pulse and PAO2 behaved similarly. Post ECT systolic BP decreased at 1 and 5 minutes. Pulse rate decreased after ECT. Conclusion: ECT under propofol is one of the most effective and safe modality of treatment for psychiatric patients under the supervision of qualified psychiatrists and anaesthesiologists and it gives more stable hemodynamic changes. (author)

Effects of oxygen partial pressure on the ferroelectric properties of pulsed laser deposited Ba0.8Sr0.2TiO3 thin films

Science.gov (United States)

Silva, J. P. B.; Sekhar, K. C.; Almeida, A.; Agostinho Moreira, J.; Pereira, M.; Gomes, M. J. M.

2013-11-01

The Ba0.8Sr0.2TiO3 thin films were grown on the Pt-Si substrate at 700 °C by using a pulsed laser deposition technique at different oxygen partial pressure (PO2) in the range of 1-20 Pa and their properties were investigated. It is observed that the PO2 during the deposition plays an important role on the tetragonal distortion ratio, surface morphology, dielectric permittivity, ferroelectric polarization, switching response, and leakage currents of the films. With an increase in PO2, the in-plane strain for the BST films changes from tensile to compressive. The films grown at 7.5 Pa show the optimum dielectric and ferroelectric properties and also exhibit the good polarization stability. It is assumed that a reasonable compressive strain, increasing the ionic displacement, and thus promotes the in-plane polarization in the field direction, could improve the dielectric permittivity. The butterfly features of the capacitance-voltage ( C- V) characteristics and the bell shape curve in polarization current were attributed to the domain reversal process. The effect of pulse amplitude on the polarization reversal behavior of the BST films grown at PO2 of 7.5 Pa was studied. The peak value of the polarization current shows exponential dependence on the electric field.

High-efficiency generation of pulsed Lyman-α radiation by resonant laser wave mixing in low pressure Kr-Ar mixture.

Science.gov (United States)

Saito, Norihito; Oishi, Yu; Miyazaki, Koji; Okamura, Kotaro; Nakamura, Jumpei; Louchev, Oleg A; Iwasaki, Masahiko; Wada, Satoshi

2016-04-04

We report an experimental generation of ns pulsed 121.568 nm Lyman-α radiation by the resonant nonlinear four-wave mixing of 212.556 nm and 845.015 nm radiation pulses providing a high conversion efficiency 1.7x10-3 with the output pulse energy 3.6 μJ achieved using a low pressure Kr-Ar mixture. Theoretical analysis shows that this efficiency is achieved due to the advantage of using (i) the high input laser intensities in combination with (ii) the low gas pressure allowing us to avoid the onset of full-scale discharge in the laser focus. In particular, under our experimental conditions the main mechanism of photoionization caused by the resonant 2-photon 212.556 nm radiation excitation of Kr atoms followed by the 1-photon ionization leads to ≈17% loss of Kr atoms and efficiency loss only by the end of the pulse. The energy of free electrons, generated by 212.556 nm radiation via (2 + 1)-photon ionization and accelerated mainly by 845.015 nm radiation, remains during the pulse below the level sufficient for the onset of full-scale discharge by the electron avalanche. Our analysis also suggests that ≈30-fold increase of 845.015 nm pulse energy can allow one to scale up the L-α radiation pulse energy towards the level of ≈100 μJ.

Control and performance improvements of a pulse compressor in use for testing accelerating structures at high power

Directory of Open Access Journals (Sweden)

Benjamin Woolley

2017-10-01

Full Text Available New developments relating to compact X-band, SLED-I type pulse compressors being developed at CERN for testing high gradient structures are described. Pulse compressors of interest take rf pulses from one or more high power klystrons with duration typically >1.5  μs and deliver up to 5 times the input power for a shorter duration <250  ns. Time domain models for pulse compressor operation with low level rf (LLRF control have been developed. Input drive amplitude and phase for each pulse is evolved with a control algorithm from the pulse compressor output for previous pulses. The goal is to deliver precise amplitude for pulses to test stands and precise amplitude and phase for pulses to accelerator systems. Control algorithms have been developed and validated experimentally.

PULSE WAVE VELOCITY AND CENTRAL AORTIC PRESSURE IN OBESE CHILDREN ACCORDING TO THE NON-INVASIVE ARTERIOGRAPHY RESULTS

Directory of Open Access Journals (Sweden)

O. V. Kozhevnikova

2013-01-01

Full Text Available The article presents information value of non-invasive arteriography, which reveals early signs of cardiovascular pathology formation in children, using a large number of trials in children. The authors examined predictors of cardiovascular catastrophes’ development, confirmed in adults: aortic wall’s stiffness, central aortic pressure and pulse pressure – that have not been sufficiently studied in children yet. The article shows that the high-technology method of non-invasive arteriography allows revealing changes of these parameters in children on the preclinical stage. It also shows their correlation with body mass index, fatty hepatosis, direct correlation of weight gain with connection of pulse wave velocity and central blood pressure and importance of follow-up evaluation of these parameters. Heterogeneity of the group of obese children in terms of these parameters is a premise for development of individual approach to control and prevention of cardiovascular complications’ development risk in childhood.

2-Dimension pulse shape discriminator for phoswich detector based on FPGA

International Nuclear Information System (INIS)

Ji Jianfeng; Liu Congzhan; Zhang Zhi

2011-01-01

It improves the data acquire system for the pulse signal based on digital front-rear pulse shape discrimination system. It adds pulse width information into the pulse's data package. Base on this, we divide the pulse event process into two process, on line coast process and offline accurate process: the online process sets a big threshold, just save the data of the event below this threshold; the offline process uses the acquired data, get the pulse amplitude and pulse width, and then according the spectrum's real shape, set the accurate threshold. this design resolves the problem that the detector's decay time change with the temperature; at the same time, it can correct the system's distortion when the input signal at small amplitude, improves the discrimination system's accuracy. (authors)

Design of a ns-pulse generator with microwave studio

NARCIS (Netherlands)

Huiskamp, T.; Voeten, S.J.; Pemen, A.J.M.

2012-01-01

In this paper we present a design approach of a nanosecond pulse generator by using CST MICROWAVE STUDIO R . Through detailed simulation we arrive at a design for a fast rise-time variable pulse duration pulse generator which is able to produce 1–10 nanosecond pulses with tens of kilovolt amplitude.

Systolic Blood Pressure Accuracy Enhancement in the Electronic Palpation Method Using Pulse Waveform

Science.gov (United States)

2001-10-25

adrenalin) or vasodilating (Nipride or Nitromex) medicines. Also painkillers and anesthetics (Oxanest, Diprivan, Fentanyl and Rapifen) may have affected...the measurements. It is hard to distinguish the effects of medication and assess their relation to blood pressure errors and pulse shapes...CONCLUSION During this study, 51 cardiac operated patients were measured to define the effects of arterial stiffening on the accuracy of the

Computation of the effect of pipe plasticity on pressure-pulse propagation in a fluid system

International Nuclear Information System (INIS)

Youngdahl, C.K.; Kot, C.A.

1975-04-01

A simple computational model is developed for incorporating the effect of elastic-plastic deformation of piping on pressure-transient propagation in a fluid system. A computer program (PLWV) is described that incorporates this structural interaction model into a one-dimensional method-of-characteristics procedure for fluid-hammer analysis. Computed results are shown to be in good agreement with available experimental data. The most significant effect of plastic deformation is to limit the peak pressure of a pulse leaving a pipe to approximately the yield pressure of the pipe, if the pipe is sufficiently long. 7 references. (U.S.)

Pulsed microwave discharge at atmospheric pressure for NOx decomposition

International Nuclear Information System (INIS)

Baeva, M; Gier, H; Pott, A; Uhlenbusch, J; Hoeschele, J; Steinwandel, J

2002-01-01

A 3.0 GHz pulsed microwave source operated at atmospheric pressure with a pulse power of 1.4 MW, a maximum repetition rate of 40 Hz, and a pulse length of 3.5 μs is experimentally studied with respect to the ability to remove NO x from synthetic exhaust gases. Experiments in gas mixtures containing N 2 /O 2 /NO with typically 500 ppm NO are carried out. The discharge is embedded in a high-Q microwave resonator, which provides a reliable plasma ignition. Vortex flow is applied to the exhaust gas to improve gas treatment. Concentration measurements by Fourier transform infrared spectroscopy confirm an NO x reduction of more than 90% in the case of N 2 /NO mixtures. The admixture of oxygen lowers the reductive potential of the reactor, but NO x reduction can still be observed up to 9% O 2 concentration. Coherent anti-Stokes Raman scattering technique is applied to measure the vibrational and rotational temperature of N 2 . Gas temperatures of about 400 K are found, whilst the vibrational temperature is 3000-3500 K in pure N 2 . The vibrational temperature drops to 1500 K when O 2 and/or NO are present. The randomly distributed relative frequency of occurrence of selected breakdown field intensities is measured by a calibrated, short linear-antenna. The breakdown field strength in pure N 2 amounts to 2.2x10 6 V m -1 , a value that is reproducible within 2%. In the case of O 2 and/or NO admixture, the frequency distribution of the breakdown field strength scatters more and extends over a range from 3 to 8x10 6 V m -1

Pulsed water jet generated by pulse multiplication

Czech Academy of Sciences Publication Activity Database

Dvorský, R.; Sitek, Libor; Sochor, T.

2016-01-01

Roč. 23, č. 4 (2016), s. 959-967 ISSN 1330-3651 R&D Projects: GA MŠk(CZ) LO1406; GA MŠk ED2.1.00/03.0082 Institutional support: RVO:68145535 Keywords : high- pressure pulses * pulse intensifier * pulsed water jet * water hammer effect Subject RIV: JQ - Machines ; Tools Impact factor: 0.723, year: 2016 http://hrcak.srce.hr/163752?lang=en

Transitions between corona, glow, and spark regimes of nanosecond repetitively pulsed discharges in air at atmospheric pressure

OpenAIRE

Pai , David ,; Lacoste , Deanna ,; Laux , C.

2010-01-01

International audience; In atmospheric pressure air preheated from 300 to 1000 K, the nanosecond repetitively pulsed (NRP) method has been used to generate corona, glow, and spark discharges. Experiments have been performed to determine the parameter space (applied voltage, pulse repetition frequency, ambient gas temperature, and interelectrode gap distance) of each discharge regime. In particular, the experimental conditions necessary for the glow regime of NRP discharges have been determine...

Continuous processing of polymers in repetitively pulsed atmospheric pressure discharges with moving surfaces and gas flow

Energy Technology Data Exchange (ETDEWEB)

Bhoj, Ananth N [Department of Chemical and Biomolecular Engineering, University of Illinois, Urbana, IL 61801 (United States); Kushner, Mark J [Department of Electrical and Computer Engineering, Iowa State University, Ames, IA 50011 (United States)

2007-11-21

Atmospheric pressure corona discharges are industrially employed to treat large areas of commodity polymer sheets by creating new surface functional groups. The most common processes use oxygen containing discharges to affix oxygen to hydrocarbon polymers, thereby increasing their surface energy and wettability. The process is typically continuous and is carried out in a web configuration with film speeds of tens to hundreds of cm s{sup -1}. The densities and relative abundances of functional groups depend on the gas composition, gas flow rate and residence time of the polymer in the discharge zone which ultimately determine the magnitude and mole fractions of reactive fluxes to the surface. In this paper, results are discussed from a two-dimensional computational investigation of the atmospheric pressure plasma functionalization of a moving polypropylene sheet in repetitively pulsed He/O{sub 2}/H{sub 2}O discharges. O and OH typically initiate surface processing by hydrogen abstraction. These species are regenerated during every plasma pulse but are also largely consumed during the inter-pulse period. Longer-lived species such as O{sub 3} accumulate over many pulses and convect downstream with the gas flow. Optimizing the interplay between local rapid reactions, such as H abstraction which occurs dominantly in the discharge zone, and non-local slower processes, such as surface-surface reactions, may enable the customization of the relative abundance of surface functional groups.

Continuous processing of polymers in repetitively pulsed atmospheric pressure discharges with moving surfaces and gas flow

International Nuclear Information System (INIS)

Bhoj, Ananth N; Kushner, Mark J

2007-01-01

Atmospheric pressure corona discharges are industrially employed to treat large areas of commodity polymer sheets by creating new surface functional groups. The most common processes use oxygen containing discharges to affix oxygen to hydrocarbon polymers, thereby increasing their surface energy and wettability. The process is typically continuous and is carried out in a web configuration with film speeds of tens to hundreds of cm s -1 . The densities and relative abundances of functional groups depend on the gas composition, gas flow rate and residence time of the polymer in the discharge zone which ultimately determine the magnitude and mole fractions of reactive fluxes to the surface. In this paper, results are discussed from a two-dimensional computational investigation of the atmospheric pressure plasma functionalization of a moving polypropylene sheet in repetitively pulsed He/O 2 /H 2 O discharges. O and OH typically initiate surface processing by hydrogen abstraction. These species are regenerated during every plasma pulse but are also largely consumed during the inter-pulse period. Longer-lived species such as O 3 accumulate over many pulses and convect downstream with the gas flow. Optimizing the interplay between local rapid reactions, such as H abstraction which occurs dominantly in the discharge zone, and non-local slower processes, such as surface-surface reactions, may enable the customization of the relative abundance of surface functional groups

Study on the characteristics of barrier free surface discharge driven by repetitive nanosecond pulses at atmospheric pressure

Energy Technology Data Exchange (ETDEWEB)

Lei, Pang; Qiaogen, Zhang [State Key Laboratory of Electrical Insulation and Power Equipment, Xi' an Jiaotong University, Xi' an 710049 (China); Kun, He [China Electric Power Research Institute, Beijing 100192 (China); Chunliang, Liu [State Key Laboratory for Physical Electronics and Devices, Xi' an Jiaotong University, Xi' an 710049 (China)

2016-05-15

Nanosecond pulsed plasma has an enormous potential in many applications. In this paper, the characteristics of barrier free nanosecond pulsed surface discharge are investigated by the use of an actuator with a strip-strip film electrode configuration, including the effect of electrode width and the gap distance on the plasma morphology and electrical characteristics at atmospheric pressure. It was found that it is relative easier to generate a quasi uniform discharge with a thinner electrode width and a smaller gap distance. The underlying physical mechanism was also discussed. Besides that, the influence of airflow on repetitive pulsed surface discharge was examined. By comparing to the discharge produced by two different pulse waveforms in airflows, we found that the discharge driven by a faster pulse behaves more stable. Finally, a model was developed to analyze the interaction of the airflow and the discharge channels.

Probability of cavitation for single ultrasound pulses applied to tissues and tissue-mimicking materials.

Science.gov (United States)

Maxwell, Adam D; Cain, Charles A; Hall, Timothy L; Fowlkes, J Brian; Xu, Zhen

2013-03-01

In this study, the negative pressure values at which inertial cavitation consistently occurs in response to a single, two-cycle, focused ultrasound pulse were measured in several media relevant to cavitation-based ultrasound therapy. The pulse was focused into a chamber containing one of the media, which included liquids, tissue-mimicking materials, and ex vivo canine tissue. Focal waveforms were measured by two separate techniques using a fiber-optic hydrophone. Inertial cavitation was identified by high-speed photography in optically transparent media and an acoustic passive cavitation detector. The probability of cavitation (P(cav)) for a single pulse as a function of peak negative pressure (p(-)) followed a sigmoid curve, with the probability approaching one when the pressure amplitude was sufficient. The statistical threshold (defined as P(cav) = 0.5) was between p(-) = 26 and 30 MPa in all samples with high water content but varied between p(-) = 13.7 and >36 MPa in other media. A model for radial cavitation bubble dynamics was employed to evaluate the behavior of cavitation nuclei at these pressure levels. A single bubble nucleus with an inertial cavitation threshold of p(-) = 28.2 megapascals was estimated to have a 2.5 nm radius in distilled water. These data may be valuable for cavitation-based ultrasound therapy to predict the likelihood of cavitation at various pressure levels and dimensions of cavitation-induced lesions in tissue. Copyright © 2013 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.

Amplitude modulation of atomic wave functions. Final report

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-11-01

The major theoretical advance has been to show that one can modulate Rydberg wave functions using either of two methods: (1) the amplitude modulation technique which depends on autoionization to deplete part of the wave function, or (2) a phase modulation method, which uses a change in the core potential to create a localized phase shift in the wave function. Essentially, these two methods can both be seen as using the core potential to change the Rydberg wave function, using the imaginary part of the potential to do amplitude modulation, or using the real part of the potential to do phase modulation. This work will be published as the authors acquire experimental results which show the differences between the two methods. One of the results of this theoretical study is that the initial proposal to study Barium 6snd states had a significant flaw. Neither the autoionization time, nor the quantum defect shifts are very large in these cases. This means that the modulation is relatively small. This shows itself primarily in the difficulty of seeing significant population redistribution into different 6snd states. The authors intend to correct this in the next funding cycle either: (a) by using the more quickly decaying Ba 6pnf states to modulate 6snd states, or (b) by using Sr 5 snd states, as outlined in this report. Their first, low power experiments are complete. These experiments have used two pulses to do a temporal version of the Ramsey separated oscillatory fields excitation. The two pulses are generated by passing the single pulse through a Michelson-Morley interferometer, which is computer controlled to sweep one arm through 2.5 {micro}m in steps of 10 nm. The second pulse`s excitation interferes with that of the first pulse, and so the total excitation has a sinusoidal variation (with a time period equal to the optical period) on top of a constant background. The amplitude of the total variation should decay at half of the rate decay rate of the autoionizing

A comparison between characteristics of atmospheric-pressure plasma jets sustained by nanosecond- and microsecond-pulse generators in helium

International Nuclear Information System (INIS)

Zhang, Cheng; Shao, Tao; Wang, Ruixue; Yan, Ping; Zhou, Zhongsheng; Zhou, Yixiao

2014-01-01

Power source is an important parameter that can affect the characteristics of atmospheric-pressure plasma jets (APPJs), because it can play a key role on the discharge characteristics and ionization process of APPJs. In this paper, the characteristics of helium APPJs sustained by both nanosecond-pulse and microsecond-pulse generators are compared from the aspects of plume length, discharge current, consumption power, energy, and optical emission spectrum. Experimental results showed that the pulsed APPJ was initiated near the high-voltage electrode with a small curvature radius, and then the stable helium APPJ could be observed when the applied voltage increased. Moreover, the discharge current of the nanosecond-pulse APPJ was larger than that of the microsecond-pulse APPJ. Furthermore, although the nanosecond-pulse generator consumed less energy than the microsecond-pulse generator, longer plume length, larger instantaneous power per pulse and stronger spectral line intensity could be obtained in the nanosecond-pulse excitation case. In addition, some discussion indicated that the rise time of the applied voltage could play a prominent role on the generation of APPJs

Social support and loneliness in college students: effects on pulse pressure reactivity to acute stress.

Science.gov (United States)

O'Donovan, Aoife; Hughes, Brian

2007-01-01

Socially supportive relationships at university may buffer against psychological stress in students, particularly in those experiencing loneliness. To examine the relation of social support at university and loneliness with pulse pressure (PP) reactivity to acute psychological stress in a sample of first-year undergraduate students. Sixty-five female, adolescent, first-year university students. Pulse pressure (PP) was calculated as the arithmetic difference between systolic blood pressure and diastolic blood pressure, which were measured during a resting baseline and during a stressful reading task. The difference between baseline and reading task PP represents PP reactivity. The Social Support at University Scale (SSUS) was used to assess social support availability in university, and the Revised UCLA Loneliness Scale was used to assess loneliness. Hierarchical linear regression was used to examine main and interactive effects of SSUS and loneliness on PP change scores, and simple slopes were computed to assist in the interpretation of interaction effects. Social support at university was associated with lower PP reactivity in students reporting medium (t = -2.03, p = .04) or high levels of loneliness (t = -2.93, p = .004), but not in those reporting low levels of loneliness (t = -0.20, p = .83). Psychosocial interventions designed to increase social support available at university, and targeted at students experiencing loneliness may buffer against the harmful effects of acute stressors in lonely first-year students.

Low amplitude rhythmic contraction frequency in human detrusor strips correlates with phasic intravesical pressure waves.

Science.gov (United States)

Colhoun, Andrew F; Speich, John E; Cooley, Lauren F; Bell, Eugene D; Barbee, R Wayne; Guruli, Georgi; Ratz, Paul H; Klausner, Adam P

2017-08-01

Low amplitude rhythmic contractions (LARC) occur in detrusor smooth muscle and may play a role in storage disorders such as overactive bladder and detrusor overactivity. The purpose of this study was to determine whether LARC frequencies identified in vitro from strips of human urinary bladder tissue correlate with in vivo LARC frequencies, visualized as phasic intravesical pressure (p ves ) waves during urodynamics (UD). After IRB approval, fresh strips of human urinary bladder were obtained from patients. LARC was recorded with tissue strips at low tension (rhythmic frequency similar to the in vitro LARC frequency quantified in human urinary bladder tissue strips. Further refinements of this technique may help identify subsets of individuals with LARC-mediated storage disorders.

Custom pulse generator for RPC testing

International Nuclear Information System (INIS)

Gil, A.; Castro, E.; Diaz, J.; Fonte, P.; Garzon, J.A.; Montes, N.; Zapata, M.

2009-01-01

We present a pulse generator able to generate pulses statistically similar to the ones produced by RPC cells. The device generates up to four arrays of fast and narrow random-like pulses. Polarity, maximum amplitudes, widths and pulse rate in each channel may be modified independently in order to simulate different RPC setups and environments. This portable and cost-effective pulse generator is a versatile instrument for testing FE-Electronics and different real detector features related with the signal propagation inside the detector. It has been developed in the framework of the ESTRELA project of the HADES experiment at GSI.

A compact bipolar pulse-forming network-Marx generator based on pulse transformers.

Science.gov (United States)

Zhang, Huibo; Yang, Jianhua; Lin, Jiajin; Yang, Xiao

2013-11-01

A compact bipolar pulse-forming network (PFN)-Marx generator based on pulse transformers is presented in this paper. The high-voltage generator consisted of two sets of pulse transformers, 6 stages of PFNs with ceramic capacitors, a switch unit, and a matched load. The design is characterized by the bipolar pulse charging scheme and the compact structure of the PFN-Marx. The scheme of bipolar charging by pulse transformers increased the withstand voltage of the ceramic capacitors in the PFNs and decreased the number of the gas gap switches. The compact structure of the PFN-Marx was aimed at reducing the parasitic inductance in the generator. When the charging voltage on the PFNs was 35 kV, the matched resistive load of 48 Ω could deliver a high-voltage pulse with an amplitude of 100 kV. The full width at half maximum of the load pulse was 173 ns, and its rise time was less than 15 ns.

Effect of high hydrostatic pressure, ultrasound and pulsed electric fields on milk composition and characteristics

Directory of Open Access Journals (Sweden)

Irena Jeličić

2012-03-01

Full Text Available High hydrostatic pressure, ultrasonication and pulsed eletrcic fields (PEF belong to novel food processing methods which are mostly implemented in combination with moderate temperatures and/ or in combination with each other in order to provide adequate microbiological quality with minimal losses of nutritional value. All of three mentioned methods have been intensively investigated for the purpose of inactivation and reduction of foodborne microorganisms present in milk and dairy products. However, a large number of scientific researches have been dedicated to investigation of impact of these methods on changes in constituents like milk fat, milk proteins and lactose as well as changes in mechanisms like renneting properties and coagulation of milk. The aim of this research was to give an overview of changes in milk constituents induced by high hydrostatic pressure, ultrasonification and pulsed electric field treatments as well as to suggest how these changes could improve conventional processes in the dairy industry.

Transmission of reactive pulsed laser deposited VO{sub 2} films in the THz domain

Energy Technology Data Exchange (ETDEWEB)

Émond, Nicolas; Hendaoui, Ali; Ibrahim, Akram; Al-Naib, Ibraheem; Ozaki, Tsuneyuki; Chaker, Mohamed, E-mail: chaker@emt.inrs.ca

2016-08-30

Highlights: • Synthesis of vanadium dioxide (VO{sub 2}) thin films as a function of oxygen pressure (2–25 mTorr) using Reactive Pulsed Laser Deposition (RPLD). • Characterization of RPLD-grown VO{sub 2} thin films in the THz frequency range. • THz switches and/or sensors require VO{sub 2} films deposited at low oxygen pressure (i.e. low transition temperature, large amplitude contrast of THz transmission, narrow hysteresis width). • THz optical memory applications require VO{sub 2} films deposited at high oxygen pressure (broad hysteresis width). - Abstract: This work reports on the characteristics of the insulator-to-metal transition (IMT) of reactive pulsed laser deposited vanadium dioxide (VO{sub 2}) films in the terahertz (THz) frequency range, namely the transition temperature T{sub IMT}, the amplitude contrast of the THz transmission over the IMT ΔA, the transition sharpness ΔT and the hysteresis width ΔH. XRD analysis shows the sole formation of VO{sub 2} monoclinic structure with an enhancement of (011) preferential orientation when varying the O{sub 2} pressure (P{sub O2}) during the deposition process from 2 to 25 mTorr. THz transmission measurements as a function of temperature reveal that VO{sub 2} films obtained at low P{sub O2} exhibit low T{sub IMT}, large ΔA, and narrow ΔH. Increasing P{sub O2} results in VO{sub 2} films with higher T{sub IMT}, smaller ΔA, broader ΔH and asymmetric hysteresis loop. The good control of the VO{sub 2} IMT features in the THz domain could be further exploited for the development of advanced smart devices, such as ultrafast switches, modulators, memories and sensors.

Performance investigation of the pulse and Campbelling modes of a fission chamber using a Poisson pulse train simulation code

Energy Technology Data Exchange (ETDEWEB)

Elter, Zs. [CEA, DEN, DER, Instrumentation, Sensors and Dosimetry Laboratory, Cadarache, F-13108 Saint-Paul-lez-Durance (France); Chalmers University of Technology, Department of Applied Physics, Division of Nuclear Engineering, SE-412 96 Göteborg (Sweden); Jammes, C., E-mail: christian.jammes@cea.fr [CEA, DEN, DER, Instrumentation, Sensors and Dosimetry Laboratory, Cadarache, F-13108 Saint-Paul-lez-Durance (France); Pázsit, I. [Chalmers University of Technology, Department of Applied Physics, Division of Nuclear Engineering, SE-412 96 Göteborg (Sweden); Pál, L. [Centre for Energy Research, Hungarian Academy of Sciences, H-1525 Budapest 114, POB 49 (Hungary); Filliatre, P. [CEA, DEN, DER, Instrumentation, Sensors and Dosimetry Laboratory, Cadarache, F-13108 Saint-Paul-lez-Durance (France)

2015-02-21

The detectors of the neutron flux monitoring system of the foreseen French GEN-IV sodium-cooled fast reactor (SFR) will be high temperature fission chambers placed in the reactor vessel in the vicinity of the core. The operation of a fission chamber over a wide-range neutron flux will be feasible provided that the overlap of the applicability of its pulse and Campbelling operational modes is ensured. This paper addresses the question of the linearity of these two modes and it also presents our recent efforts to develop a specific code for the simulation of fission chamber pulse trains. Our developed simulation code is described and its overall verification is shown. An extensive quantitative investigation was performed to explore the applicability limits of these two standard modes. It was found that for short pulses the overlap between the pulse and Campbelling modes can be guaranteed if the standard deviation of the background noise is not higher than 5% of the pulse amplitude. It was also shown that the Campbelling mode is sensitive to parasitic noise, while the performance of the pulse mode is affected by the stochastic amplitude distributions.

Arterial compliance in patients with cirrhosis: stroke volume-pulse pressure ratio as simplified index

DEFF Research Database (Denmark)

Fuglsang, S; Bendtsen, F; Christensen, E

2001-01-01

Arterial function may be altered in patients with cirrhosis. We determined compliance of the arterial tree (C(1)) in relation to systemic and splanchnic hemodynamic derangement and clinical variables. C(1) and the stroke volume-pulse pressure index (SV/PP) were significantly higher (+62% and +40%...... predictors of SV/PP (P abnormalities in the arterial compliance of these patients....

Combined treatment with mild heat, manothermosonication and pulsed electric fields reduces microbial growth in milk

OpenAIRE

Halpin, R. M.; Cregenzan-Alberti, O.; Whyte, P.; Lyng, J. G.; Noci, F.

2013-01-01

In recent years, there has been considerable interest in non-thermal milk processing. The objective of the present study was to assess the efficacy of two non-thermal technologies (manothermosonication; MTS, and pulsed electric fields; PEF) in comparison to thermal pasteurisation, by assessing the microbial levels of each of these milk samples post-processing. Homogenised milk was subjected to MTS (frequency; 20 kHz, amplitude; 27.9 μm, pressure; 225 kPa) at two temperatures (37 °C or 55 °C),...

Improved stabilization scheme for computerized pulse-height analyzers

International Nuclear Information System (INIS)

Cohn, C.E.

1982-01-01

A stabilization scheme has been adapted from a 24-bit to a 16-bit computer. A precision pulse generator produces tagged reference pulses alternately of high and low amplitude. Gain and zero corrections are obtained from these and applied to each normal event. Provisions are made to make the system robust against pileup corruption of the reference pulses. (orig.)

Diode-pumped, single frequency Nd:YLF laser for 60-beam OMEGA laser pulse-shaping system

International Nuclear Information System (INIS)

Okishev, A.V.; Seka, W.

1997-01-01

The operational conditions of the OMEGA pulse-shaping system require an extremely reliable and low-maintenance master oscillator. The authors have developed a diode-pumped, single-frequency, pulsed Nd:YLF laser for this application. The laser generates Q-switched pulses of ∼160-ns duration and ∼10-microJ energy content at the 1,053-nm wavelength with low amplitude fluctuations (<0.6% rms) and low temporal jitter (<7 ns rms). Amplitude and frequency feedback stabilization systems have been used for high long-term amplitude and frequency stability

Performances of Hybrid Amplitude Shape Modulation for UWB Communications Systems over AWGN Channel in a Single and Multi-User Environment

Directory of Open Access Journals (Sweden)

M. Herceg

2009-09-01

Full Text Available This paper analyzes the performance of the hybrid Amplitude Shape Modulation (h-ASM scheme for the time-hopping ultra-wideband (TH-UWB communication systems in the single and multi-user environment. h-ASM is the combination of Pulse Amplitude Modulation (PAM and Pulse Shape Modulation (PSM based on modified Hermite pulses (MHP. This scheme is suitable for high rate data transmission applications because b = log2(MN bits can be mapped with one waveform. The channel capacity and error probability over AWGN channel are derived and compared with other modulation schemes.

Pulse reverse plating for integrated magnetics on Si

International Nuclear Information System (INIS)

Roy, S.; Connell, A.; Ludwig, M.; Wang, N.; O'Donnell, T.; Brunet, M.; McCloskey, P.; OMathuna, C.; Barman, A.; Hicken, R.J.

2005-01-01

Thin film microtransformers have been fabricated on silicon with Ni 45 Fe 55 as a core material. Fractal/dendritic growths are observed in the patterned cores in DC electroplating due to the enhancement of localized current density at defect/nucleation sites. A 'pulser' device was made in house to produce forward and reverse current of the required amplitude for a particular duration. The combination of a low amplitude long (millisecond) forward pulse and a short (microsecond) high-amplitude reverse pulse gave dendrite-free plated cores with a uniform thickness and alloy composition over a 3D topology of a microrough substrate surface. Finally, we characterized the material in situ by small signal electrical measurements, and with MOKE hysteresis loops measured on a complete device

Extremum seeking to control the amplitude and frequency of a pulsed jet for bluff body drag reduction

Science.gov (United States)

Brackston, Rowan D.; Wynn, Andrew; Morrison, Jonathan F.

2016-10-01

Feedback control of fluid flows presents a challenging problem due to nonlinear dynamics and unknown optimal operating conditions. Extremum seeking control presents a suitable method for many flow control situations but involves its own challenges. In this paper, we provide a brief analysis of the extremum seeking method, with attention to modifications that we find to be advantageous. In particular, we present an adaptation for optimisation of the frequency of a harmonic input signal, a common scenario for open-loop flow control systems. We then present results from the experimental implementation of our modified method to the open-loop control system of Oxlade et al. (J Fluid Mech 770:305-318, 2015), an axisymmetric bluff-body wake, forced by a pulsed jet. We find that the system is able to achieve optimal operating conditions in both the amplitude and frequency of the harmonic input signal, and is able to largely reject the disturbances arising from measurements of a highly turbulent flow. We finally show the ability of the extremum seeking system to adapt to changing conditions.

Effects of pulse-to-pulse residual species on discharges in repetitively pulsed discharges through packed bed reactors

Science.gov (United States)

Kruszelnicki, Juliusz; Engeling, Kenneth W.; Foster, John E.; Kushner, Mark J.

2016-09-01

Atmospheric pressure dielectric barrier discharges (DBDs) sustained in packed bed reactors (PBRs) are being investigated for conversion of toxic and waste gases, and CO2 removal. These discharges are repetitively pulsed having varying flow rates and internal geometries, which results in species from the prior pulse still being in the discharge zone at the time the following discharge pulse occurs. A non-negligible residual plasma density remains, which effectively acts as preionization. This residual charge changes the discharge properties of subsequent pulses, and may impact important PBR properties such as chemical selectivity. Similarly, the residual neutral reactive species produced during earlier pulses will impact the reaction rates on subsequent pulses. We report on results of a computational investigation of a 2D PBR using the plasma hydrodynamics simulator nonPDPSIM. Results will be discussed for air flowing though an array of dielectric rods at atmospheric pressure. The effects of inter-pulse residual species on PBR discharges will be quantified. Means of controlling the presence of residual species in the reactor through gas flow rate, pulse repetition, pulse width and geometry will be described. Comparisons will be made to experiments. Work supported by US DOE Office of Fusion Energy Science and the National Science Foundation.

Temporal evolution of atmosphere pressure plasma jets driven by microsecond pulses with positive and negative polarities

Science.gov (United States)

Shao, Tao; Yang, Wenjin; Zhang, Cheng; Fang, Zhi; Zhou, Yixiao; Schamiloglu, Edl

2014-09-01

Current-voltage characteristics, discharge images, and optical spectra of atmospheric pressure plasma jets (APPJs) are studied using a microsecond pulse length generator producing repetitive output pulses with different polarities. The experimental results show that the APPJs excited by the pulses with positive polarity have longer plume, faster propagation speed, higher power, and more excited species, such as \\text{N}2 , O, He, \\text{N}2+ , than that with the negatively excited APPJs. The images taken using an intensified charge-coupled device show that the APPJs excited by pulses with positive polarity are characterized by a bullet-like structure, while the APPJs excited by pulses with negative polarity are continuous. The propagation speed of the APPJs driven by a microsecond pulse length generator is about tens of km/s, which is similar to the APPJs driven by a kHz frequency sinusoidal voltage source. The analysis shows that the space charge accumulation effect plays an important role during the discharge. The transient enhanced electric field induced by the accumulated ions between the needle-like electrode and the nozzle in the APPJs excited by pulses with negative polarity enhances electron field emission from the cathode, which is illustrated by the bright line on the time-integrated images. This makes the shape of the APPJ excited using pulses with negative polarity different from the bullet-like shape of the APPJs excited by pulses with positive polarity.

Amplitude Variations in Pulsating Red Giants. II. Some Systematics

Science.gov (United States)

Percy, J. R.; Laing, J.

2017-12-01

In order to extend our previous studies of the unexplained phenomenon of cyclic amplitude variations in pulsating red giants, we have used the AAVSO time-series analysis package vstar to analyze long-term AAVSO visual observations of 50 such stars, mostly Mira stars. The relative amount of the variation, typically a factor of 1.5, and the time scale of the variation, typically 20-35 pulsation periods, are not significantly different in longer-period, shorter-period, and carbon stars in our sample, and they also occur in stars whose period is changing secularly, perhaps due to a thermal pulse. The time scale of the variations is similar to that in smaller-amplitude SR variables, but the relative amount of the variation appears to be larger in smaller-amplitude stars, and is therefore more conspicuous. The cause of the amplitude variations remains unclear, though they may be due to rotational modulation of a star whose pulsating surface is dominated by the effects of large convective cells.

Soft error rate analysis methodology of multi-Pulse-single-event transients

International Nuclear Information System (INIS)

Zhou Bin; Huo Mingxue; Xiao Liyi

2012-01-01

As transistor feature size scales down, soft errors in combinational logic because of high-energy particle radiation is gaining more and more concerns. In this paper, a combinational logic soft error analysis methodology considering multi-pulse-single-event transients (MPSETs) and re-convergence with multi transient pulses is proposed. In the proposed approach, the voltage pulse produced at the standard cell output is approximated by a triangle waveform, and characterized by three parameters: pulse width, the transition time of the first edge, and the transition time of the second edge. As for the pulse with the amplitude being smaller than the supply voltage, the edge extension technique is proposed. Moreover, an efficient electrical masking model comprehensively considering transition time, delay, width and amplitude is proposed, and an approach using the transition times of two edges and pulse width to compute the amplitude of pulse is proposed. Finally, our proposed firstly-independently-propagating-secondly-mutually-interacting (FIP-SMI) is used to deal with more practical re-convergence gate with multi transient pulses. As for MPSETs, a random generation model of MPSETs is exploratively proposed. Compared to the estimates obtained using circuit level simulations by HSpice, our proposed soft error rate analysis algorithm has 10% errors in SER estimation with speed up of 300 when the single-pulse-single-event transient (SPSET) is considered. We have also demonstrated the runtime and SER decrease with the increment of P0 using designs from the ISCAS-85 benchmarks. (authors)

Plasma sterilization of polyethylene terephthalate bottles by pulsed corona discharge at atmospheric pressure.

Science.gov (United States)

Masaoka, Satoshi

2007-06-01

A pulsed power supply was used to generate a corona discharge on a polyethylene terephthalate bottle, to conduct plasma sterilization at atmospheric pressure. Before generating such a discharge, minute quantities of water were attached to the inner surface of the bottle and to the surface of a high voltage (HV) electrode inserted into the bottle. Next, high-voltage pulses of electricity were discharged between electrodes for 6.0s, while rotating the bottle. The resulting spore log reduction values of Bacillus subtilis and Aspergillus niger on the inner surface of the bottle were 5.5 and 6 or higher, respectively, and those on the HV electrode surface were each 6 or higher for both strains. The presence of the by-products gaseous ozone, hydrogen peroxide, and nitric ions resulting from the electrical discharge was confirmed.

Abnormal intra-aural pressure waves associated with death in African children with acute nontraumatic coma.

Science.gov (United States)

Gwer, Samson; Kazungu, Michael; Chengo, Eddie; Ohuma, Eric O; Idro, Richard; Birch, Tony; Marchbanks, Robert; Kirkham, Fenella J; Newton, Charles R

2015-07-01

We explored the relationship between tympanic membrane displacement (TMD) measurements, a tool to monitor intracranial pressure noninvasively, and clinical features and death in children with acute coma in Kilifi, Kenya. Between November 2007 and September 2009, we made serial TMD measurements and clinical observations on children with acute coma (Blantyre coma score (BCS) ≤ 2) on the pediatric high dependency unit of Kilifi District Hospital, and on well children presenting to the hospital's outpatient department for routine follow-up. We examined middle ear function using tympanometry and measured cardiac pulse (CPA) and respiratory pulse pressure amplitudes (RPA) using the TMD analyzer. We recruited 75 children (32 (43%) females; median age 3.3 (IQR: 2.0, 4.3) years). Twenty-one (28%) children died. Higher TMD measurements predicted death. Adjusting for diagnosis, every 50 nl rise in both semirecumbent and recumbent CPA was associated with increased odds of death associated with intracranial herniation (OR: 1.61, 95% confidence interval (CI): 1.07, 2.41; P = 0.02 and OR: 1.35, 95% CI: 1.10, 1.66; P ≤ 0.01 respectively). Raised TMD pulse pressure measurements are associated with death and may be useful in detecting and monitoring risk of intracranial herniation and intracranial pressure in childhood coma.

Radial Pressure Pulse and Heart Rate Variability in Heat- and Cold-Stressed Humans

Directory of Open Access Journals (Sweden)

Chin-Ming Huang

2011-01-01

Full Text Available This study aims to explore the effects of heat and cold stress on the radial pressure pulse (RPP and heart rate variability (HRV. The subjects immersed their left hand into 45°C and 7°C water for 2 minutes. Sixty healthy subjects (age 25±4 yr; 29 men and 31 women were enrolled in this study. All subjects underwent the supine temperature measurements of the bilateral forearms, brachial arterial blood pressure, HRV and RPP with a pulse analyzer in normothermic conditions, and thermal stresses. The power spectral low-frequency (LF and high-frequency (HF components of HRV decreased in the heat test and increased in the cold test. The heat stress significantly reduced radial augmentation index (AIr (P<.05, but the cold stress significantly increased AIr (P<.01. The spectral energy of RPP did not show any statistical difference in 0∼10 Hz region under both conditions, but in the region of 10∼50 Hz, there was a significant increase (P<.01 in the heat test and a significant decrease in the cold test (P<.01. The changes in AIr induced by heat and cold stress were significantly negatively correlated with the spectral energy in the region of 10∼50 Hz (SE10−50 Hz but not in the region of 0∼10 Hz (SE0−10 Hz. The results demonstrated that the SE10−50 Hz, which only possessed a small percentage in total pulse energy, presented more physiological characteristics than the SE0−10 Hz under the thermal stresses.

Radial Pressure Pulse and Heart Rate Variability in Heat- and Cold-Stressed Humans

Science.gov (United States)

Huang, Chin-Ming; Chang, Hsien-Cheh; Kao, Shung-Te; Li, Tsai-Chung; Wei, Ching-Chuan; Chen, Chiachung; Liao, Yin-Tzu; Chen, Fun-Jou

2011-01-01

This study aims to explore the effects of heat and cold stress on the radial pressure pulse (RPP) and heart rate variability (HRV). The subjects immersed their left hand into 45°C and 7°C water for 2 minutes. Sixty healthy subjects (age 25 ± 4 yr; 29 men and 31 women) were enrolled in this study. All subjects underwent the supine temperature measurements of the bilateral forearms, brachial arterial blood pressure, HRV and RPP with a pulse analyzer in normothermic conditions, and thermal stresses. The power spectral low-frequency (LF) and high-frequency (HF) components of HRV decreased in the heat test and increased in the cold test. The heat stress significantly reduced radial augmentation index (AIr) (P < .05), but the cold stress significantly increased AIr (P < .01). The spectral energy of RPP did not show any statistical difference in 0 ~ 10 Hz region under both conditions, but in the region of 10 ~ 50 Hz, there was a significant increase (P < .01) in the heat test and a significant decrease in the cold test (P < .01). The changes in AIr induced by heat and cold stress were significantly negatively correlated with the spectral energy in the region of 10 ~ 50 Hz (SE10−50 Hz) but not in the region of 0 ~ 10 Hz (SE0−10 Hz). The results demonstrated that the SE10−50 Hz, which only possessed a small percentage in total pulse energy, presented more physiological characteristics than the SE0−10 Hz under the thermal stresses. PMID:21113292

Using a heterodyne vibrometer in combination with pulse excitation for primary calibration of ultrasonic hydrophones in amplitude and phase

Science.gov (United States)

Weber, Martin; Wilkens, Volker

2017-08-01

A high-frequency vibrometer was used with ultrasonic pulse excitation in order to perform a primary hydrophone calibration. This approach enables the simultaneous characterization of the amplitude and phase transfer characteristic of ultrasonic hydrophones. The method allows a high frequency resolution in a considerably short time for the measurement. Furthermore, the uncertainty contributions of this approach were investigated and quantified. A membrane hydrophone was calibrated and the uncertainty budget for this measurement was determined. The calibration results are presented up to 70~\\text{MHz} . The measurement results show good agreement with the results obtained by sinusoidal burst excitation through the use of the vibrometer and by a homodyne laser interferometer, with RMS deviation of approximately 3% -4% in the frequency range from 1 to 60~\\text{MHz} . Further hydrophones were characterized up to 100~\\text{MHz} with this procedure to demonstrate the suitability for very high frequency calibration.

Experimental study on a co-axial pulse tube cryocooler driven by a small thermoacoustic stirling engine

Science.gov (United States)

Chen, M.; Ju, L. Y.; Hao, H. X.

2014-01-01

Small scale thermoacoustic heat engines have advantages in fields like space exploration and domestic applications considering small space occupation and ease of transport. In the present paper, the influence of resonator diameter on the general performance of a small thermoacoustic Stirling engine was experimentally investigated using helium as the working gas. Reducing the diameter of the resonator appropriately is beneficial for lower onset heating temperature, lower frequency and higher pressure amplitude. Based on the pressure distribution in the small thermoacoustic engine, an outlet for the acoustic work transmission was made to combine the engine and a miniature co-axial pulse tube cooler. The cooling performance of the whole refrigeration system without any moving part was tested. Experimental results showed that further efforts are required to optimize the engine performance and its match with the co-axial pulse tube cooler in order to obtain better cooling performance, compared with its original operating condition, driven by a traditional electrical linear compressor.

Improvement of stability of sinusoidally driven atmospheric pressure plasma jet using auxiliary bias voltage

Directory of Open Access Journals (Sweden)

Hyun-Jin Kim

2015-12-01

Full Text Available In this study, we have proposed the auxiliary bias pulse scheme to improve the stability of atmospheric pressure plasma jets driven by an AC sinusoidal waveform excitation source. The stability of discharges can be significantly improved by the compensation of irregular variation in memory voltage due to the effect of auxiliary bias pulse. From the parametric study, such as the width, voltage, and onset time of auxiliary bias pulse, it has been demonstrated that the auxiliary bias pulse plays a significant role in suppressing the irregular discharges caused by the irregular variation in memory voltage and stable discharge can be initiated with the termination of the auxiliary bias pulse. As a result of further investigating the effects of the auxiliary pulse scheme on the jet stability under various process conditions such as the distance between the jet head and the counter electrode, and carrier gas flow, the jet stability can be improved by adjusting the amplitude and number of the bias pulse depending on the variations in the process conditions.

High-pressure single-crystal neutron diffraction (to 20 kbar) using a pulsed source: Preliminary investigation of Tl3PSe4

International Nuclear Information System (INIS)

Alkire, R.W.; Larson, A.C.; Vergamini, P.J.; Schirber, J.E.; Morosin, B.

1985-01-01

A new technique is described for performing high-pressure single-crystal neutron diffraction [up to 20 kbar (2GPa) at room temperature], using a BeCu pressure cell, an area detector and the Los Alamos National Laboratory pulsed neutron source. Success of this method depends on the increase in information available with a multi-wavelength pulse neutron source, a novel orientation of a cylindrically symmetric pressure cell with its axis coincident with the neutron beam and a specific crystal orientation within the pressure cell. Bragg scattering from the pressure cell is avoided and background for a given 2theta is constant. For a crystal of orthorhombic or higher symmetry oriented with the incident beam passing midway between the major lattice vectors, it will be possible to refine a complete three-dimensional structure with data collected from only one pressure loading. Preliminary investigations of Tl 3 PSe 4 lattice parameters (space group Pcmn) at 15(1)kbar yielded linear compressibilities (. 1000 in kbar -1 ) of Ksub(a) = 1.05(8), Ksub(b) = 1.50(10), Ksub(c) = 1.20(8). The anisotropic compressibility is explained by examination of the ambient-pressure room-temperature structure. (orig.)

Production of atmospheric pressure diffuse nanosecond pulsed dielectric barrier discharge using the array needles-plate electrode in air

International Nuclear Information System (INIS)

Yang Dezheng; Wang Wenchun; Jia Li; Nie Dongxia; Shi Hengchao

2011-01-01

In this paper, a bidirectional high pulse voltage with 20 ns rising time is employed to generate an atmospheric pressure diffuse dielectric barrier discharge using the array needles-plate electrode configuration. Both double needle and multiple needle electrode configurations nanosecond pulsed dielectric barrier discharges are investigated. It is found that a diffuse discharge plasma with low gas temperature can be obtained, and the plasma volume increases with the increase of the pulse peak voltage, but remains almost constant with the increase of the pulse repetition rate. In addition to showing the potential application on a topographically nonuniform surface treatment of the discharge, the multiple needle-plate electrode configuration with different needle-plate electrode gaps are also employed to generate diffuse discharge plasma.

Amplitude-to-code converter for photomultipliers operating at high loadings

International Nuclear Information System (INIS)

Arkhangel'skij, B.V.; Evgrafov, G.N.; Pishchal'nikov, Yu.M.; Shuvalov, R.S.

1982-01-01

An 11-bit amplitude-to-code converter intended for the analysis of photomultiplier pulses under high loadings is described. To decrease the volume of digit electronics in the converter an analog memory on capacities is envisaged. A well-known bridge circuit with diodes on the main carriers is selected as a gating circuit. The gate control is realized by a switching circuit on fast-response transistors with boundary frequency of 1.2-1.5 GHz. The converter main characteristics are given, namely, maximum output signal amplitude equal to -1.5 V, minimum pulse selection duration of 10 ns, maximum number of counts at Usub(input)=-1.0 V and tsub(selection)=50 ns amounting to 1400, integral nonlinearity of +-0.1%, conversion temperature instability of 0.2%/deg C in the temperature range of (+10-+40) deg C, maximum time of data storage equal to 300 ms, conversion coefficient instability of 0.42 counts, number of channels in a unit CAMAC block equal to 12

Modeling study on the effects of pulse rise rate in atmospheric pulsed discharges

Science.gov (United States)

Zhang, Yuan-Tao; Wang, Yan-Hui

2018-02-01

In this paper, we present a modeling study on the discharge characteristics driven by short pulsed voltages, focusing on the effects of pulse rise rate based on the fluid description of atmospheric plasmas. The numerical results show that the breakdown voltage of short pulsed discharge is almost linearly dependent on the pulse rise rate, which is also confirmed by the derived equations from the fluid model. In other words, if the pulse rise rate is fixed as a constant, the simulation results clearly suggest that the breakdown voltage is almost unchanged, although the amplitude of pulsed voltage increases significantly. The spatial distribution of the electric field and electron density are given to reveal the underpinning physics. Additionally, the computational data and the analytical expression also indicate that an increased repetition frequency can effectively decrease the breakdown voltage and current density, which is consistent with the experimental observation.

Variation in resistance of natural isolates of Staphylococcus aureus to heat, pulsed electric field and ultrasound under pressure.

Science.gov (United States)

Rodríguez-Calleja, J M; Cebrián, G; Condón, S; Mañas, P

2006-05-01

To study and compare the resistance of 15 Staphylococcus aureus isolates to heat, pulsed electric field (PEF) and ultrasound (UW) under pressure (manosonication, MS). Survival curves to heat (58 degrees C), to PEF (22 kV cm(-1), 2 micros square wave pulses) and to UW under pressure (117 microm, 20 kHz, 200 kPa) were obtained and inactivation parameters (decimal reduction times for heat and UW under pressure, and b-values for PEF) were calculated. A wide resistance variation to heat treatment, but not to PEF and MS, was observed amongst the 15 strains. There was no relationship between the resistances to the three physical agents studied. Staphylococcus aureus was relatively resistant to MS but sensitive to PEF. Heat resistance varied with strain and was positively correlated to carotenoid pigment content. Results would help in defining safe food preservation processes. Care should be taken to choose the most adequate strain of S. aureus to model food preservation processing.

Magnetic discharge accelerating diode for the gas-filled pulsed neutron generators based on inertial confinement of ions

International Nuclear Information System (INIS)

Kozlovskij, K I; Shikanov, A E; Vovchenko, E D; Shatokhin, V L; Isaev, A A; Martynenko, A S

2016-01-01

The paper deals with magnetic discharge diode module with inertial electrostatic ions confinement for the gas-filled pulsed neutron generators. The basis of the design is geometry with the central hollow cathode surrounded by the outer cylindrical anode and electrodes made of permanent magnets. The induction magnitude about 0.1-0.4 T in the central region of the discharge volume ensures the confinement of electrons in the space of hollow (virtual) cathode and leads to space charge compensation of accelerated ions in the centre. The research results of different excitation modes in pulsed high-voltage discharge are presented. The stable form of the volume discharge preserveing the shape and amplitude of the pulse current in the pressure range of 10 -3 -10 -1 Torr and at the accelerating voltage up to 200 kV was observed. (paper)

Influence of duration and rate of pulse rise of the applied voltage on ozone concentration in the barrier glow discharge

International Nuclear Information System (INIS)

Krasnyj, V.V.; Klosovski, A.V.; Knysh, A.S.; Shvets, O.M.; Taran, V.S.; Tereshin, V.I.

2005-01-01

The barrier glow discharge between two planar electrodes, covered with dielectric, is studied under high-voltage pulsed power supply. Wide applications of such type of discharges, in particular, for ozone production, stimulated a number of investigations in this direction. In this work we investigated the dependence of ozone concentration on the duration and the rate of pulse rise of the applied voltage. The thyristor converter circuit with the shortening of input pulses on the base of the saturable throttle was used for the realization of this task. The output pulses with amplitude up to 15 kV, repetition frequency of 1 kHz, pulse duration of 0.3 μs (or 7 μs) and the rate of pulse rise of 0.1 μs were generated with this scheme. Measurements of the ozone concentration produced in the air mixture have shown that its value increased by factor two with variation of the rate of pulse rise from 0.5 μs to 0.1 μs (for pulse duration of 7 μs). The dependence of the ozone concentration on the variation of air mixture pressure in the discharge gap of reactor was investigated also. It was shown proportional increase of the output concentration of ozone with increasing the pressure value. Spectroscopic measurements carried out in the ultraviolet spectrum made it possible to analyze changing the concentration of ozone and nitric components. (author)

The physics of pulsed streamer discharge in high pressure air and applications to engine techonologies

Science.gov (United States)

Lin, Yung-Hsu

The goal of this dissertation is to study high pressure streamers in air and apply it to diesel engine technologies. Nanosecond scale pulsed high voltage discharges in air/fuel mixtures can generate radicals which in turn have been shown to improve combustion efficiency in gasoline fueled internal combustion engines. We are exploring the possibility to extend such transient plasma generation and expected radical species generation to the range of pressures encountered in compression-ignition (diesel) engines having compression ratios of ˜20:1, thereby improving lean burning efficiency and extending the range of lean combustion. At the beginning of this dissertation, research into streamer discharges is reviewed. Then, we conducted experiments of streamer propagation at high pressures, calculated the streamer velocity based on both optical and electrical measurements, and the similarity law was checked by analyzing the streamer velocity as a function of the reduced electric field, E/P. Our results showed that the similarity law is invalid, and an empirical scaling factor, E/√P, is obtained and verified by dimensional analysis. The equation derived from the dimensional analysis will be beneficial to proper electrode and pulse generator design for transient plasma assisted internal engine experiments. Along with the high pressure study, we applied such technique on diesel engine to improve the fuel efficiency and exhaust treatment. We observed a small effect of transient plasma on peak pressure, which implied that transient plasma has the capability to improve the fuel consumption. In addition, the NO can be reduced effectively by the same technique and the energy cost is 30 eV per NO molecule.

Optical UWB pulse generator using an N tap microwave photonic filter and phase inversion adaptable to different pulse modulation formats.

Science.gov (United States)

Bolea, Mario; Mora, José; Ortega, Beatriz; Capmany, José

2009-03-30

We propose theoretically and demonstrate experimentally an optical architecture for flexible Ultra-Wideband pulse generation. It is based on an N-tap reconfigurable microwave photonic filter fed by a laser array by using phase inversion in a Mach-Zehnder modulator. Since a large number of positive and negative coefficients can be easily implemented, UWB pulses fitted to the FCC mask requirements can be generated. As an example, a four tap pulse generator is experimentally demonstrated which complies with the FCC regulation. The proposed pulse generator allows different pulse modulation formats since the amplitude, polarity and time delay of generated pulse is controlled.

Experimental Investigation of Propagation and Reflection Phenomena in Finite Amplitude Sound Beams.

Science.gov (United States)

Averkiou, Michalakis Andrea

Measurements of finite amplitude sound beams are compared with theoretical predictions based on the KZK equation. Attention is devoted to harmonic generation and shock formation related to a variety of propagation and reflection phenomena. Both focused and unfocused piston sources were used in the experiments. The nominal source parameters are piston radii of 6-25 mm, frequencies of 1-5 MHz, and focal lengths of 10-20 cm. The research may be divided into two parts: propagation and reflection of continuous-wave focused sound beams, and propagation of pulsed sound beams. In the first part, measurements of propagation curves and beam patterns of focused pistons in water, both in the free field and following reflection from curved targets, are presented. The measurements are compared with predictions from a computer model that solves the KZK equation in the frequency domain. A novel method for using focused beams to measure target curvature is developed. In the second part, measurements of pulsed sound beams from plane pistons in both water and glycerin are presented. Very short pulses (less than 2 cycles), tone bursts (5-30 cycles), and frequency modulated (FM) pulses (10-30 cycles) were measured. Acoustic saturation of pulse propagation in water is investigated. Self-demodulation of tone bursts and FM pulses was measured in glycerin, both in the near and far fields, on and off axis. All pulse measurements are compared with numerical results from a computer code that solves the KZK equation in the time domain. A quasilinear analytical solution for the entire axial field of a self-demodulating pulse is derived in the limit of strong absorption. Taken as a whole, the measurements provide a broad data base for sound beams of finite amplitude. Overall, outstanding agreement is obtained between theory and experiment.

Audibility of high harmonics in a periodic pulse

NARCIS (Netherlands)

Duifhuis, H.

1970-01-01

A periodic pulse consisting of sufficiently narrow pulses has a frequency spectrum which contains all harmonics with equal amplitude. Owing to the limited resolving power of the hearing organ, only the low harmonics can be perceived separately. The high harmonics are heard together as one complex

Experimental and theoretical investigations on the dynamic response of EBR-II ducts under pressure pulse loading

International Nuclear Information System (INIS)

Chopra, P.S.; Srinivas, S.

1975-01-01

In order to assess the potential damage to hexagonal subassembly ducts (cans) that may result from rapid gas release from a failed element the EBR-II project has conducted experiments and analyses. Additional experimental and analytical investigations are now being conducted to assure fail-safety of the ducts. Fail-safety is defined as the ability of a duct to withstand pressure pulses from failed elements during all reactor conditions without damage to adjacent ducts or any other problems in fuel handling. The results of 93 EBR-II duct tests conducted primarily by Koenig have been reported previously. The results of empirical correlations of some of these tests to determine the influence of several variables on the pressure pulse experienced by a duct and on the duct deformation are presented. The variables include the type of gas contained in the simulated element (tube), the element and duct materials, the presence or absence of flow restrictors in the element, and the way gas was released. 8 references. (auth)

Electromagnetic pulses in a strongly magnetized electron-positron plasma

International Nuclear Information System (INIS)

Yu, M.Y.; Rao, N.N.

1985-01-01

The conditions for the existence of large-amplitude localized electromagnetic wave pulses in an electron-positron plasma penetrated by a very strong ambient magnetic field are obtained. It is shown that such pulses can exist in pulsar polar magnetospheres. 12 references

125-GHz Microwave Signal Generation Employing an Integrated Pulse Shaper

DEFF Research Database (Denmark)

Liao, Shasha; Ding, Yunhong; Dong, Jianji

2017-01-01

We propose and experimentally demonstrate an on-chip pulse shaper for 125-GHz microwave waveform generation. The pulse shaper is implemented based on a silicon-on-insulator (SOI) platform that has a structure with eight-tap finite impulse response (FIR) and there is an amplitude modulator on each...... of the generated microwave waveforms is larger than 100 GHz, and it has wide bandwidth when changing the time delay of the adjacent taps and compactness, capability for integration with electronics and small power consumption are also its merits.......We propose and experimentally demonstrate an on-chip pulse shaper for 125-GHz microwave waveform generation. The pulse shaper is implemented based on a silicon-on-insulator (SOI) platform that has a structure with eight-tap finite impulse response (FIR) and there is an amplitude modulator on each...

Method for measuring the stochastic properties of corona and partial-discharge pulses

International Nuclear Information System (INIS)

Van Brunt, R.J.; Kulkarni, S.V.

1989-01-01

A new method is described for measuring the stochastic behavior of corona and partial-discharge pulses which utilizes a pulse selection and sorting circuit in conjunction with a computer-controlled multichannel analyzer to directly measure various conditional and unconditional pulse-height and pulse-time-separation distributions. From these measured distributions it is possible to determine the degree of correlation between successive discharge pulses. Examples are given of results obtained from measurements on negative, point-to-plane (Trichel-type) corona pulses in a N 2 /O 2 gas mixture which clearly demonstrate that the phenomenon is inherently stochastic in the sense that development of a discharge pulse is significantly affected by the amplitude of and time separation from the preceding pulse. It is found, for example, that corona discharge pulse amplitude and time separation from an earlier pulse are not independent random variables. Discussions are given about the limitations of the method, sources of error, and data analysis procedures required to determine self-consistency of the various measured distributions

CAMAC differential pulse discriminator-counter

International Nuclear Information System (INIS)

Tselikov, N.V.

1987-01-01

Differential pulse discriminator-counter for Moessbauer spectrometer is described. Input pulse setting into the channel is performed according to the following algorithm: the pulse is transmitted to the channel depending on the fact whether the preceding pulse has got to the discrimination window or not. The circuit does not contain delay lines, taking into account the delay of a signal from the upper level discriminator in relation to the lower level discriminator signal, which is connected with input pulse rise finite time, which in turn allows one to reduce the discriminator dead time up to the operation time of threshold circuits. The pulse counting rate is 150 MHz, input signal amplitude is ±3 V, dead time is 6 ns, delay time from input to output is 14 ns. The unit is made in CAMAC system

The role of pulse shape in motor cortex transcranial magnetic stimulation using full-sine stimuli.

Directory of Open Access Journals (Sweden)

Igor Delvendahl

Full Text Available A full-sine (biphasic pulse waveform is most commonly used for repetitive transcranial magnetic stimulation (TMS, but little is known about how variations in duration or amplitude of distinct pulse segments influence the effectiveness of a single TMS pulse to elicit a corticomotor response. Using a novel TMS device, we systematically varied the configuration of full-sine pulses to assess the impact of configuration changes on resting motor threshold (RMT as measure of stimulation effectiveness with single-pulse TMS of the non-dominant motor hand area (M1. In young healthy volunteers, we (i compared monophasic, half-sine, and full-sine pulses, (ii applied two-segment pulses consisting of two identical half-sines, and (iii manipulated amplitude, duration, and current direction of the first or second full-sine pulse half-segments. RMT was significantly higher using half-sine or monophasic pulses compared with full-sine. Pulses combining two half-sines of identical polarity and duration were also characterized by higher RMT than full-sine stimuli resulting. For full-sine stimuli, decreasing the amplitude of the half-segment inducing posterior-anterior oriented current in M1 resulted in considerably higher RMT, whereas varying the amplitude of the half-segment inducing anterior-posterior current had a smaller effect. These findings provide direct experimental evidence that the pulse segment inducing a posterior-anterior directed current in M1 contributes most to corticospinal pathway excitation. Preferential excitation of neuronal target cells in the posterior-anterior segment or targeting of different neuronal structures by the two half-segments can explain this result. Thus, our findings help understanding the mechanisms of neural stimulation by full-sine TMS.

Preparation of TiO sub 2 nanoparticles by pulsed laser ablation: Ambient pressure dependence of crystallization

CERN Document Server

Matsubara, M; Yamaki, T; Itoh, H; Abe, H

2003-01-01

Pulsed laser ablation (PLA) with a KrF excimer laser was used to prepare fine particles of titanium dioxide (TiO sub 2). The ablation in an atmosphere of Ar and O sub 2 (5:5) at total pressures of >= 1 Torr led to the formation of TiO sub 2 nanoparticles composed of anatase and rutile structures without any suboxides. The weight fraction of the rutile/anatase crystalline phases was dependent on the pressure of the Ar/O sub 2 gas. The TiO sub 2 nanoparticles had a spherical shape and their size, ranging from 10 and 14 nm, also appeared to be dependent on the ambient pressure. (author)

Probabilistic SSME blades structural response under random pulse loading

Science.gov (United States)

Shiao, Michael; Rubinstein, Robert; Nagpal, Vinod K.

1987-01-01

The purpose is to develop models of random impacts on a Space Shuttle Main Engine (SSME) turbopump blade and to predict the probabilistic structural response of the blade to these impacts. The random loading is caused by the impact of debris. The probabilistic structural response is characterized by distribution functions for stress and displacements as functions of the loading parameters which determine the random pulse model. These parameters include pulse arrival, amplitude, and location. The analysis can be extended to predict level crossing rates. This requires knowledge of the joint distribution of the response and its derivative. The model of random impacts chosen allows the pulse arrivals, pulse amplitudes, and pulse locations to be random. Specifically, the pulse arrivals are assumed to be governed by a Poisson process, which is characterized by a mean arrival rate. The pulse intensity is modelled as a normally distributed random variable with a zero mean chosen independently at each arrival. The standard deviation of the distribution is a measure of pulse intensity. Several different models were used for the pulse locations. For example, three points near the blade tip were chosen at which pulses were allowed to arrive with equal probability. Again, the locations were chosen independently at each arrival. The structural response was analyzed both by direct Monte Carlo simulation and by a semi-analytical method.

The flip-over effect in pulsed laser deposition: Is it relevant at high background gas pressures?

International Nuclear Information System (INIS)

Ojeda-G-P, Alejandro; Schneider, Christof W.; Döbeli, Max; Lippert, Thomas; Wokaun, Alexander

2015-01-01

Highlights: • The flip-over effect in PLD is observed up to high deposition pressures. • Consistent congruent transfer of the target composition is generally not correct. • The choice of deposition pressure can change the film composition strongly. • Large compositional changes appear at high off-axis angles and large spot sizes. - Abstract: In pulsed laser deposition the use of a rectangular or elliptical beam spot with a non 1:1 aspect ratio leads to the so called flip-over effect. Here, the longest dimension of the laser spot results in the shortest direction of plasma plume expansion. This effect has been mainly reported for vacuum depositions of single element targets and is particularly noticeable when the aspect ratio of the beam spot is large. We investigate the flip-over effect in vacuum and at three relevant background-gas pressures for pulsed laser deposition using a La 0.4 Ca 0.6 MnO 3 target by measuring the thickness dependence of the deposited material as a function of angle. The film thicknesses and compositions are determined by Rutherford backscattering and argon is used to reduce the influence of additional chemical reactions in the plasma. The results show the prevalence of the flip-over effect for all pressures except for the highest, i.e. 1 × 10 −1 mbar, where the film thickness is constant for all angles. The composition profiles show noticeable compositional variations of up to 30% with respect to the target material depending on the background gas pressure, the angular location, and the laser spot dimensions.

Association of pulse wave velocity and pulse pressure with decline in kidney function.

Science.gov (United States)

Kim, Chang Seong; Kim, Ha Yeon; Kang, Yong Un; Choi, Joon Seok; Bae, Eun Hui; Ma, Seong Kwon; Kim, Soo Wan

2014-05-01

The association between arterial stiffness and decline in kidney function in patients with mild to moderate chronic kidney disease (CKD) is not well established. This study investigated whether pulse wave velocity (PWV) and pulse pressure (PP) are independently associated with glomerular filtration rate (GFR) and rapid decline in kidney function in early CKD. Carotid femoral PWV (cfPWV), brachial-ankle PWV (baPWV), and PP were measured in a cohort of 913 patients (mean age, 63±10 years; baseline estimated GFR, 84±18 mL/min/1.73 m(2) ). Estimated GFR was measured at baseline and at follow-up. The renal outcome examined was rapid decline in kidney function (estimated GFR loss, >3 mL/min/1.73 m(2) per year). The median follow-up duration was 3.2 years. Multivariable adjusted linear regression model indicated that arterial PWV (both cfPWV and baPWV) and PP increased as estimated GFR declined, but neither was associated with kidney function after adjustment for various covariates. Multivariable logistic regression analysis found that cfPWV and baPWV were not associated with rapid decline in kidney function (odds ratio [OR], 1.39, 95% confidence interval [CI], 0.41-4.65; OR, 2.51, 95% CI, 0.66-9.46, respectively), but PP was (OR, 1.22, 95% CI, 1.01-1.48; P=.045). Arterial stiffness assessed using cfPWV and baPWV was not correlated with lower estimated GFR and rapid decline in kidney function after adjustment for various confounders. Thus, PP is an independent risk factor for rapid decline in kidney function in populations with relatively preserved kidney function (estimated GFR ≥30 mL/min/1.73 m(2) ). ©2014 Wiley Periodicals, Inc.

Effect of Pulsed Ultraviolet Light and High Hydrostatic Pressure on the Antigenicity of Almond Protein Extracts.

Science.gov (United States)

The efficacy of pulsed ultraviolet light (PUV) and high hydrostatic pressure (HHP) on reducing the IgE binding to the almond extracts, was studied using SDS-PAGE, Western Blot, and ELISA probed with human plasma containing IgE antibodies to almond allergens, and a polyclonal antibody against almond ...

Generation of longitudinally polarized terahertz pulses with field amplitudes exceeding 2 kV/cm

Science.gov (United States)

Cliffe, M. J.; Rodak, A.; Graham, D. M.; Jamison, S. P.

2014-11-01

We demonstrate the generation of near-single cycle longitudinally polarized terahertz radiation using a large-area radially biased photoconductive antenna with a longitudinal field amplitude in excess of 2 kV/cm. The 76 mm diameter antenna was photo-excited by a 0.5 mJ amplified near-infrared femtosecond laser system and biased with a voltage of up to 100 kV applied over concentric electrodes. Amplitudes for both the transverse and longitudinal field components of the source were measured using a calibrated electro-optic detection scheme. By tightly focusing the radiation emitted from the photoconductive antenna, we obtained a maximum longitudinal field amplitude of 2.22 kV/cm with an applied bias field of 38.5 kV/cm.

The detailed characteristics of positive corona current pulses in the line-to-plane electrodes

Science.gov (United States)

Xuebao, LI; Dayong, LI; Qian, ZHANG; Yinfei, LI; Xiang, CUI; Tiebing, LU

2018-05-01

The corona current pulses generated by corona discharge are the sources of the radio interference from transmission lines and the detailed characteristics of the corona current pulses from conductor should be investigated in order to reveal their generation mechanism. In this paper, the line-to-plane electrodes are designed to measure and analyze the characteristics of corona current pulses from positive corona discharges. The influences of inter-electrode gap and line diameters on the detail characteristics of corona current pulses, such as pulse amplitude, rise time, duration time and repetition frequency, are carefully analyzed. The obtained results show that the pulse amplitude and the repetition frequency increase with the diameter of line electrode when the electric fields on the surface of line electrodes are same. With the increase of inter-electrode gap, the pulse amplitude and the repetition frequency first decrease and then turn to be stable, while the rise time first increases and finally turns to be stable. The distributions of electric field and space charges under the line electrodes are calculated, and the influences of inter-electrode gap and line electrode diameter on the experimental results are qualitatively explained.

Correlation of pulse wave velocity with left ventricular mass in patients with hypertension once blood pressure has been normalized

Directory of Open Access Journals (Sweden)

Siu H. Chan

2012-02-01

Full Text Available Vascular stiffness has been proposed as a simple method to assess arterial loading conditions of the heart which induce left ventricular hypertrophy (LVH. There is some controversy as to whether the relationship of vascular stiffness to LVH is independent of blood pressure, and which measurement of arterial stiffness, augmentation index (AI or pulse wave velocity (PWV is best. Carotid pulse wave contor and pulse wave velocity of patients (n=20 with hypertension whose blood pressure (BP was under control (<140/90 mmHg with antihypertensive drug treatment medications, and without valvular heart disease, were measured. Left ventricular mass, calculated from 2D echocardiogram, was adjusted for body size using two different methods: body surface area and height. There was a significant (P<0.05 linear correlation between LV mass index and pulse wave velocity. This was not explained by BP level or lower LV mass in women, as there was no significant difference in PWV according to gender (1140.1+67.8 vs 1110.6+57.7 cm/s. In contrast to PWV, there was no significant correlation between LV mass and AI. In summary, these data suggest that aortic vascular stiffness is an indicator of LV mass even when blood pressure is controlled to less than 140/90 mmHg in hypertensive patients. The data further suggest that PWV is a better proxy or surrogate marker for LV mass than AI and the measurement of PWV may be useful as a rapid and less expensive assessment of the presence of LVH in this patient population.

IAE pulsed electrostatic accelerator

International Nuclear Information System (INIS)

Afanas'ev, V.P.; Ganzhelyuk, M.L.; Kozlov, L.D.; Koltypin, E.A.; Molchanov, Yu.D.; Otroshchenko, G.A.; Yan'kov, G.B.

1976-01-01

The modernized pulse electrostatic accelerator using the klystron ion grouping and the beam interruption system prior to acceleration is described. The accelerator is modernized in order to improve parameters of a current pulse and to decrease the background in the measurement room. The ion beam of needed dimensions is obtained with the help of a high-frequency source and a beam grouping and deflection system. The general view of the beam grouping and deflection system is shown. The ion beam forming process is considered in detail. The modernized electrostatic accelerator permits to obtain a pulse current with a pulse length of 1.5 ns and an amplitude of 1.5 - 2 μA. With the repetition frequency of 2 MHz, the average target current is about 6 μA

Generation of uniform low-temperature plasma in a pulsed non-self-sustained glow discharge with a large-area hollow cathode

Energy Technology Data Exchange (ETDEWEB)

Akhmadeev, Yu. H.; Denisov, V. V., E-mail: volodyadenisov@yandex.ru; Koval, N. N.; Kovalsky, S. S.; Lopatin, I. V.; Schanin, P. M.; Yakovlev, V. V. [Russian Academy of Sciences, Institute of High-Current Electronics, Siberian Branch (Russian Federation)

2017-01-15

Generation of plasma in a pulsed non-self-sustained glow discharge with a hollow cathode with an area of ≥2 m{sup 2} at gas pressures of 0.4–1 Pa was studied experimentally. At an auxiliary arc-discharge current of 100 A and a main discharge voltage of 240 V, a pulse-periodic glow discharge with a current amplitude of 370 A, pulse duration of 340 μs, and repetition rate of 1 kHz was obtained. The possibility of creating a uniform gas-discharge plasma with a density of up to 10{sup 12} cm{sup −3} and an electron temperature of 1 eV in a volume of >0.2 m{sup 3} was demonstrated. Such plasma can be efficiently used to treat material surfaces and generate pulsed ion beams with a current density of up to 15 mA/cm{sup 2}.

Pulse Pressure, Instead of Brachium-Ankle Pulse Wave Velocity, is Associated with Reduced Kidney Function in a Chinese Han Population

Directory of Open Access Journals (Sweden)

Linpei Jia

2017-03-01

Full Text Available Background/Aims: In this study, we aim to investigate the association between renal function and arterial stiffness in a Chinese Han population, and further to discuss the effects of smoking on renal function. Methods: We collected the data of the brachium-ankle pulse wave velocity (baPWV, blood pressure, blood chemistry and smoking status. Then, the multiple linear regression was done to explore the relationship between estimated glomerular filtration (eGFR and baPWV. Further, the parameters were compared among the four groups divided according to the quartiles of baPWV. Finally, the baPWV, eGFR and albuminuria values were compared between smokers and non-smokers. Results: baPWV is associated with eGFR in the correlation analysis and univariate linear regression model. After adjustment, the pulse pressure (PP instead of baPWV showed a significant association with eGFR. Nevertheless, the eGFR values differed among the four baPWV groups; the baPWV values were significantly higher in the subjects at the CKD (eGFR<60 mL/min/1.73 m2 and the early CKD stage (eGFR60–80 mL/min/1.73 m2. The baPWV values and the ratio of proteinuria were significantly increased in smokers. Conclusion: PP but not baPWV is a predictor of declined renal function. Smokers have worse arterial stiffness and worse renal function.

System and process for pulsed multiple reaction monitoring

Science.gov (United States)

Belov, Mikhail E

2013-05-17

A new pulsed multiple reaction monitoring process and system are disclosed that uses a pulsed ion injection mode for use in conjunction with triple-quadrupole instruments. The pulsed injection mode approach reduces background ion noise at the detector, increases amplitude of the ion signal, and includes a unity duty cycle that provides a significant sensitivity increase for reliable quantitation of proteins/peptides present at attomole levels in highly complex biological mixtures.

The flip-over effect in pulsed laser deposition: Is it relevant at high background gas pressures?

Science.gov (United States)

Ojeda-G-P, Alejandro; Schneider, Christof W.; Döbeli, Max; Lippert, Thomas; Wokaun, Alexander

2015-12-01

In pulsed laser deposition the use of a rectangular or elliptical beam spot with a non 1:1 aspect ratio leads to the so called flip-over effect. Here, the longest dimension of the laser spot results in the shortest direction of plasma plume expansion. This effect has been mainly reported for vacuum depositions of single element targets and is particularly noticeable when the aspect ratio of the beam spot is large. We investigate the flip-over effect in vacuum and at three relevant background-gas pressures for pulsed laser deposition using a La0.4Ca0.6MnO3 target by measuring the thickness dependence of the deposited material as a function of angle. The film thicknesses and compositions are determined by Rutherford backscattering and argon is used to reduce the influence of additional chemical reactions in the plasma. The results show the prevalence of the flip-over effect for all pressures except for the highest, i.e. 1 × 10-1 mbar, where the film thickness is constant for all angles. The composition profiles show noticeable compositional variations of up to 30% with respect to the target material depending on the background gas pressure, the angular location, and the laser spot dimensions.

Dependence of adiabatic population transfer on pulse profile

Indian Academy of Sciences (India)

Control of population transfer by rapid adiabatic passage has been an established technique wherein the exact amplitude profile of the shaped pulse is considered to be insignificant. We study the effect of ultrafast shaped pulses for two-level systems, by density-matrix approach. However, we find that adiabaticity depends ...

Nanosecond pulsed laser nanostructuring of Au thin films: Comparison between irradiation at low and atmospheric pressure

Energy Technology Data Exchange (ETDEWEB)

Sánchez-Aké, C., E-mail: citlali.sanchez@ccadet.unam.mx [Centro de Ciencias Aplicadas y Desarrollo Tecnológico, Universidad Nacional Autónoma de México, Circuito Exterior S/N, C. U., Delegación Coyoacán, C.P. 04510, México D.F. (Mexico); Canales-Ramos, A. [Centro de Ciencias Aplicadas y Desarrollo Tecnológico, Universidad Nacional Autónoma de México, Circuito Exterior S/N, C. U., Delegación Coyoacán, C.P. 04510, México D.F. (Mexico); García-Fernández, T. [Universidad Autónoma de la Ciudad de México (UACM), Prolongación San Isidro 151, Col. San Lorenzo Tezonco, México D.F., C.P. 09790 (Mexico); Villagrán-Muniz, M. [Centro de Ciencias Aplicadas y Desarrollo Tecnológico, Universidad Nacional Autónoma de México, Circuito Exterior S/N, C. U., Delegación Coyoacán, C.P. 04510, México D.F. (Mexico)

2017-05-01

Highlights: • Background pressure plays an important role in NPs formation and its characteristics. • The NPs diameter and their size dispersion are smaller when irradiating in vacuum. • The plasmon resonance shifts ∼15 nm to higher frequencies when irradiating in vacuum. • Film partial ablation cannot be neglected for thickness in the range 40–80 nm. • In situ optical techniques monitor the timescale of the process and ablation dynamics. - Abstract: Au thin films with tens of nm in thickness deposited on glass substrates were irradiated with nanosecond UV (355 nm) laser pulses at atmospheric pressure and in vacuum conditions (∼600 and 10{sup −5} Torr). We studied the effect of the laser fluence (200–400 mJ/cm{sup 2}), thickness of the starting film (∼40–80 nm) and surrounding pressure on the partial ablation/evaporation of the films and the morphology of the produced nanoparticles (NPs). The dynamics of NPs formation was studied by measuring in real time the transmission of the samples upon continuous-wave laser exposure, and by means of probe beam deflection technique. The ejection of material from the film as a result of the irradiation was confirmed by time-resolved shadowgraphy technique. Experiments show that the NPs diameter and their size distribution are smaller when the irradiation is performed in vacuum regardless the laser fluence and thickness of the started film. It is also shown that the plasmon band shifts to higher frequencies with lower background pressure. The optical measurements show that the films melt and ablate during the laser pulse, but the transmission of the irradiated areas continues changing during tens of microseconds due to ejection of material and solidification of the remaining gold. Our results indicate that partial ablation cannot be neglected in nanostructuration by ns-pulsed irradiation of thin films when their thickness is in the studied range.

Generation of programmable temporal pulse shape and applications in micromachining

Science.gov (United States)

Peng, X.; Jordens, B.; Hooper, A.; Baird, B. W.; Ren, W.; Xu, L.; Sun, L.

2009-02-01

In this paper we presented a pulse shaping technique on regular solid-state lasers and the application in semiconductor micromachining. With a conventional Q-switched laser, all of the parameters can be adjusted over only limited ranges, especially the pulse width and pulse shape. However, some laser link processes using traditional laser pulses with pulse widths of a few nanoseconds to a few tens of nanoseconds tend to over-crater in thicker overlying passivation layers and thereby cause IC reliability problems. Use of a laser pulse with a special shape and a fast leading edge, such as tailored pulse, is one technique for controlling link processing. The pulse shaping technique is based on light-loop controlled optical modulation to shape conventional Q-switched solid-state lasers. One advantage of the pulse shaping technique is to provide a tailored pulse shape that can be programmed to have more than one amplitude value. Moreover, it has the capability of providing programmable tailored pulse shapes with discrete amplitude and time duration components. In addition, it provides fast rising and fall time of each pulse at fairly high repetition rate at 355nm with good beam quality. The regular-to-shaped efficiency is up to 50%. We conclude with a discussion of current results for laser processing of semiconductor memory link structures using programmable temporal pulse shapes. The processing experiments showed promising results with shaped pulse.

Relationship Between Peripheral and Psychophysical Measures of Amplitude Modulation Detection in Cochlear Implant Users.

Science.gov (United States)

Tejani, Viral D; Abbas, Paul J; Brown, Carolyn J

This study investigates the relationship between electrophysiological and psychophysical measures of amplitude modulation (AM) detection. Prior studies have reported both measures of AM detection recorded separately from cochlear implant (CI) users and acutely deafened animals, but no study has made both measures in the same CI users. Animal studies suggest a progressive loss of high-frequency encoding as one ascends the auditory pathway from the auditory nerve to the cortex. Because the CI speech processor uses the envelope of an ongoing acoustic signal to modulate pulse trains that are subsequently delivered to the intracochlear electrodes, it is of interest to explore auditory nerve responses to modulated stimuli. In addition, psychophysical AM detection abilities have been correlated with speech perception outcomes. Thus, the goal was to explore how the auditory nerve responds to AM stimuli and to relate those physiologic measures to perception. Eight patients using Cochlear Ltd. Implants participated in this study. Electrically evoked compound action potentials (ECAPs) were recorded using a 4000 pps pulse train that was sinusoidally amplitude modulated at 125, 250, 500, and 1000 Hz rates. Responses were measured for each pulse over at least one modulation cycle for an apical, medial, and basal electrode. Psychophysical modulation detection thresholds (MDTs) were also measured via a three-alternative forced choice, two-down, one-up adaptive procedure using the same modulation frequencies and electrodes. ECAPs were recorded from individual pulses in the AM pulse train. ECAP amplitudes varied sinusoidally, reflecting the sinusoidal variation in the stimulus. A modulated response amplitude (MRA) metric was calculated as the difference in the maximal and minimum ECAP amplitudes over the modulation cycles. MRA increased as modulation frequency increased, with no apparent cutoff (up to 1000 Hz). In contrast, MDTs increased as the modulation frequency increased. This

Large Amplitude Oscillatory Shear (LAOS) of Acrylic Emulsion-Based Pressure Sensitive Adhesives (PSAs)

Science.gov (United States)

Zhang, Sipei; Nakatani, Alan; Griffith, William

Large Amplitude Oscillatory Shear (LAOS) testing has recently taken on renewed interest in the rheological community. It is a very useful tool to probe the viscoelastic response of materials in the non-linear regime. Much of the discussion on polymers in the LAOS field has focused on melts in or near the terminal flow regime. Here we present a LAOS study conducted on a commercial rheometer for acrylic emulsion-based pressure sensitive adhesive (PSA) films in the plateau regime. The films behaved qualitatively similar over an oscillation frequency range of 0.5-5 rad/s. From Fourier transform analysis, the fifth or even the seventh order harmonic could be observed at large applied strains. From stress decomposition analysis or Lissajous curves, inter-cycle elastic softening, or type I behavior, was observed for all films as the strain increases, while intra-cycle strain hardening occurred at strains in the LAOS regime. Overall, as acid content increases, it was found that the trend in elasticity under large applied strains agreed very well with the trend in cohesive strength of the films.

A SiGe Quadrature Pulse Modulator for Superconducting Qubit State Manipulation

Science.gov (United States)

Kwende, Randy; Bardin, Joseph

Manipulation of the quantum states of microwave superconducting qubits typically requires the generation of coherent modulated microwave pulses. While many off-the-shelf instruments are capable of generating such pulses, a more integrated approach is likely required if fault-tolerant quantum computing architectures are to be implemented. In this work, we present progress towards a pulse generator specifically designed to drive superconducing qubits. The device is implemented in a commercial silicon process and has been designed with energy-efficiency and scalability in mind. Pulse generation is carried out using a unique approach in which modulation is applied directly to the in-phase and quadrature components of a carrier signal in the 1-10 GHz frequency range through a unique digital-analog conversion process designed specifically for this application. The prototype pulse generator can be digitally programmed and supports sequencing of pulses with independent amplitude and phase waveforms. These amplitude and phase waveforms can be digitally programmed through a serial programming interface. Detailed performance of the pulse generator at room temperature and 4 K will be presented.

Propagation of an asymmetric relativistic laser pulse in plasma

International Nuclear Information System (INIS)

Garuchava, D.P.; Murusidze, I.G.; Suramlishvili, G.I.; Tsintsadze, N.L.; Tskhakaya, D.D.

1997-01-01

The interaction of a relativistically intense asymmetric laser pulse with a plasma has been studied. The asymmetric shape of the pulse implies that the rise time of the leading edge of the pulse is much greater than the fall time of the trailing edge. The numerical simulation of the propagation of such a pulse through an underdense plasma has shown that relativistic self-focusing enhances the effect of ponderomotive self-channeling. The radial ponderomotive force totally expels the electrons from the axis creating a density channel, that is, cavitation occurs. A very short fall time of the trailing edge (τ l ω p <1) causes a rapid increase in the amplitude of a laser driven longitudinal electric field to values of a few GV/cm at the back of the pulse. The numerical simulation also has shown that the channel as well as the large-amplitude longitudinal field can be sustained in the range immediately behind the pulse, thus creating favorable conditions to accelerate a trailing bunch of electrons to extremely high energies. According to our model, the accelerating electric field can reach the value 10 GV/cm. copyright 1997 The American Physical Society

EVOLUTION OF FAST MAGNETOACOUSTIC PULSES IN RANDOMLY STRUCTURED CORONAL PLASMAS

International Nuclear Information System (INIS)

Yuan, D.; Li, B.; Pascoe, D. J.; Nakariakov, V. M.; Keppens, R.

2015-01-01

We investigate the evolution of fast magnetoacoustic pulses in randomly structured plasmas, in the context of large-scale propagating waves in the solar atmosphere. We perform one-dimensional numerical simulations of fast wave pulses propagating perpendicular to a constant magnetic field in a low-β plasma with a random density profile across the field. Both linear and nonlinear regimes are considered. We study how the evolution of the pulse amplitude and width depends on their initial values and the parameters of the random structuring. Acting as a dispersive medium, a randomly structured plasma causes amplitude attenuation and width broadening of the fast wave pulses. After the passage of the main pulse, secondary propagating and standing fast waves appear. Width evolution of both linear and nonlinear pulses can be well approximated by linear functions; however, narrow pulses may have zero or negative broadening. This arises because narrow pulses are prone to splitting, while broad pulses usually deviate less from their initial Gaussian shape and form ripple structures on top of the main pulse. Linear pulses decay at an almost constant rate, while nonlinear pulses decay exponentially. A pulse interacts most efficiently with a random medium with a correlation length of about half of the initial pulse width. This detailed model of fast wave pulses propagating in highly structured media substantiates the interpretation of EIT waves as fast magnetoacoustic waves. Evolution of a fast pulse provides us with a novel method to diagnose the sub-resolution filamentation of the solar atmosphere

Association of pulse pressure with new-onset atrial fibrillation in patients with hypertension and left ventricular hypertrophy

DEFF Research Database (Denmark)

Larstorp, Anne Cecilie K; Ariansen, Inger; Gjesdal, Knut

2012-01-01

, and mean arterial pressure. When evaluated in the same model, the predictive effect of systolic and diastolic blood pressures together was similar to that of PP. In this population of patients with hypertension and left ventricular hypertrophy, PP was the strongest single blood pressure predictor of new......Previous studies have found pulse pressure (PP), a marker of arterial stiffness, to be an independent predictor of atrial fibrillation (AF) in general and hypertensive populations. We examined whether PP predicted new-onset AF in comparison with other blood pressure components in the Losartan...... Intervention For Endpoint reduction in hypertension study, a double-blind, randomized (losartan versus atenolol), parallel-group study, including 9193 patients with hypertension and electrocardiographic left ventricular hypertrophy. In 8810 patients with neither a history of AF nor AF at baseline, Minnesota...

Extremely Short Optical Pulses and Ads/CFT Compliance

Directory of Open Access Journals (Sweden)

Konobeeva N.N.

2015-01-01

Full Text Available Dynamics of few cycle optical pulses in non-Fermi liquid was considered. Energy spectrum of non-Fermi liquid was taken from the AdS/CFT compliance. Conditions of quasiparticle excitation existence were defined. Non-Fermi liquid parameters impact on the shape of few cycle pulses were estimated. It was shown that extremely short optical pulse propagation in the non-Fermi liquid is a stable pattern. The value of chemical potential has a significant impact on extremely short pulse shape. An increase in initial pulse amplitude does not result in pulse-shape distortions under its propagation in considered medium that is why the non-Fermi liquid can be used in applications inherent in extremely short pulse processing.

The flip-over effect in pulsed laser deposition: Is it relevant at high background gas pressures?

Energy Technology Data Exchange (ETDEWEB)

Ojeda-G-P, Alejandro [Paul Scherrer Institut, General Energy Research Department, 5232 Villigen-PSI (Switzerland); Schneider, Christof W., E-mail: christof.schneider@psi.ch [Paul Scherrer Institut, General Energy Research Department, 5232 Villigen-PSI (Switzerland); Döbeli, Max [Ion Beam Physics, ETH Zurich, CH-8093 Zurich (Switzerland); Lippert, Thomas; Wokaun, Alexander [Paul Scherrer Institut, General Energy Research Department, 5232 Villigen-PSI (Switzerland)

2015-12-01

Highlights: • The flip-over effect in PLD is observed up to high deposition pressures. • Consistent congruent transfer of the target composition is generally not correct. • The choice of deposition pressure can change the film composition strongly. • Large compositional changes appear at high off-axis angles and large spot sizes. - Abstract: In pulsed laser deposition the use of a rectangular or elliptical beam spot with a non 1:1 aspect ratio leads to the so called flip-over effect. Here, the longest dimension of the laser spot results in the shortest direction of plasma plume expansion. This effect has been mainly reported for vacuum depositions of single element targets and is particularly noticeable when the aspect ratio of the beam spot is large. We investigate the flip-over effect in vacuum and at three relevant background-gas pressures for pulsed laser deposition using a La{sub 0.4}Ca{sub 0.6}MnO{sub 3} target by measuring the thickness dependence of the deposited material as a function of angle. The film thicknesses and compositions are determined by Rutherford backscattering and argon is used to reduce the influence of additional chemical reactions in the plasma. The results show the prevalence of the flip-over effect for all pressures except for the highest, i.e. 1 × 10{sup −1} mbar, where the film thickness is constant for all angles. The composition profiles show noticeable compositional variations of up to 30% with respect to the target material depending on the background gas pressure, the angular location, and the laser spot dimensions.

Dynamic calibration of piezoelectric transducers for ballistic high-pressure measurement

Directory of Open Access Journals (Sweden)

Elkarous Lamine

2016-01-01

Full Text Available The development of a dynamic calibration standard for high-amplitude pressure piezoelectric transducers implies the implementation of a system which can provide reference pressure values with known characteristics and uncertainty. The reference pressure must be issued by a sensor, as a part of a measuring chain, with a guaranteed traceability to an international standard. However, this operation has not been completely addressed yet until today and is still calling further investigations. In this paper, we introduce an experimental study carried out in order to contribute to current efforts for the establishment of a reference dynamic calibration method. A suitable practical calibration method based on the calculation of the reference pressure by measurement of the displacement of the piston in contact with an oil-filled cylindrical chamber is presented. This measurement was achieved thanks to a high speed camera and an accelerometer. Both measurements are then compared. In the first way, pressure was generated by impacting the piston with a free falling weight and, in the second way, with strikers of known weights and accelerated to the impact velocities with an air gun. The aim of the experimental setup is to work out a system which may generate known hydraulic pressure pulses with high-accuracy and known uncertainty. Moreover, physical models were also introduced to consolidate the experimental study. The change of striker’s velocities and masses allows tuning the reference pressure pulses with different shapes and, therefore, permits to sweep a wide range of magnitudes and frequencies.

The detection and estimation of spurious pulses

International Nuclear Information System (INIS)

1976-01-01

Spurious pulses which may interfere with the counting of particles can sometimes easily be detected by integral counting as a function of amplification or by pulse-height analysis. However, in order to estimate their count rate, more elaborate methods based on their time relationship are needed. Direct techniques (delayed coincidences, use of a multichannel analyser in time mode, time-to-amplitude conversion) and gating techniques (simple subtraction, correlation counting, pulsed sources, modulo counting) are discussed. These techniques are compared to each other and their application to various detectors is studied as well as the influence of a dead time on spurious pulses

Nonlinear shaping of a two-dimensional ultrashort ionizing pulse

International Nuclear Information System (INIS)

Sergeev, A.; Vanin, E.; Stenflo, L.; Anderson, D.; Lisak, M.; Quiroga-Teixeiro, M.L.

1992-01-01

A theoretical description of ultrashort ionizing wave pulses is presented by means of two different models where the ionization rate increases or decreases, respectively, as a function of the electric field amplitude. We show that the pulse evolves either into a horse-shoe or a horn-type structure in the time-space domain. In some parameter regions the intensity of the pulse can also increase. (au)

Job strain associated with increases in ambulatory blood and pulse pressure during and after work hours among female hotel room cleaners.

Science.gov (United States)

Feaster, Matt; Krause, Niklas

2018-06-01

Previously documented elevated hypertension rates among Las Vegas hotel room cleaners are hypothesized to be associated with job strain. Job strain was assessed by questionnaire. Ambulatory blood pressure (ABP) was recorded among 419 female cleaners from five hotels during 18 waking hours. Multiple linear regression models assessed associations of job strain with ABP and pulse pressure for 18-h, work hours, and after work hours. Higher job strain was associated with increased 18-h systolic ABP, after work hours systolic ABP, and ambulatory pulse pressure. Dependents at home but not social support at work attenuated effects. Among hypertensive workers, job strain effects were partially buffered by anti-hypertensive medication. High job strain is positively associated with blood pressure among female hotel workers suggesting potential for primary prevention at work. Work organizational changes, stress management, and active ABP surveillance and hypertension management should be considered for integrated intervention programs. © 2018 Wiley Periodicals, Inc.

Pulsed electric field sensor based on original waveform measurement

International Nuclear Information System (INIS)

Ma Liang; Wu Wei; Cheng Yinhui; Zhou Hui; Li Baozhong; Li Jinxi; Zhu Meng

2010-01-01

The paper introduces the differential and original waveform measurement principles for pulsed E-field, and develops an pulsed E-field sensor based on original waveform measurement along with its theoretical correction model. The sensor consists of antenna, integrator, amplifier and driver, optic-electric/electric-optic conversion module and transmission module. The time-domain calibration in TEM cell indicates that, its risetime response is shorter than 1.0 ns, and the output pulse width at 90% of the maximum amplitude is wider than 10.0 μs. The output amplitude of the sensor is linear to the electric field intensity in a dynamic range of 20 dB. The measurement capability can be extended to 10 V/m or 50 kV/m by changing the system's antenna and other relative modules. (authors)

Pulse-shaping strategies in short-pulse fiber amplifiers

Energy Technology Data Exchange (ETDEWEB)

Schimpf, Damian Nikolaus

2010-02-09

Ultrashort pulse lasers are an important tool in scientific and industrial applications. However, many applications are demanding higher average powers from these ultrashort pulse sources. This can be achieved by combining direct diode pumping with novel gain media designs. In particular, ultrashort pulse fiber lasers are now delivering average powers in the kW range. However, the design of fiber lasers, producing pulses with high peak-powers, is challenging due to the impact of nonlinear effects. To significantly reduce these detrimental effects in ultrashort pulse fiber amplifers, the combination of chirped pulse amplification (CPA) and large mode area fibers is employed. Using these methods, the pulse energy of fiber lasers has been steadily increasing for the past few years. Recently, a fiber-based CPA-system has been demonstrated which produces pulse energies of around 1 mJ. However, both the stretching and the enlargement of the mode area are limited, and therefore, the impact of nonlinearity is still noticed in systems employing such devices. The aim of this thesis is the analysis of CPA-systems operated beyond the conventional nonlinear limit, which corresponds to accumulated nonlinear phase-shifts around 1 rad. This includes a detailed discussion of the influence of the nonlinear effect self-phase modulation on the output pulse of CPA-systems. An analytical model is presented. Emphasis is placed on the design of novel concepts to control the impact of self-phase modulation. Pulse-shaping is regarded as a powerful tool to accomplish this goal. Novel methods to control the impact of SPM are experimentally demonstrated. The design of these concepts is based on the theoretical findings. Both amplitude- and phase-shaping are studied. Model-based phase-shaping is implemented in a state-of-the-art fiber CPA-system. The influence of the polarization state is also highlighted. Additionally, existing techniques and recent advances are put into context. (orig.)

Pulse-shaping strategies in short-pulse fiber amplifiers

International Nuclear Information System (INIS)

Schimpf, Damian Nikolaus

2010-01-01

Ultrashort pulse lasers are an important tool in scientific and industrial applications. However, many applications are demanding higher average powers from these ultrashort pulse sources. This can be achieved by combining direct diode pumping with novel gain media designs. In particular, ultrashort pulse fiber lasers are now delivering average powers in the kW range. However, the design of fiber lasers, producing pulses with high peak-powers, is challenging due to the impact of nonlinear effects. To significantly reduce these detrimental effects in ultrashort pulse fiber amplifers, the combination of chirped pulse amplification (CPA) and large mode area fibers is employed. Using these methods, the pulse energy of fiber lasers has been steadily increasing for the past few years. Recently, a fiber-based CPA-system has been demonstrated which produces pulse energies of around 1 mJ. However, both the stretching and the enlargement of the mode area are limited, and therefore, the impact of nonlinearity is still noticed in systems employing such devices. The aim of this thesis is the analysis of CPA-systems operated beyond the conventional nonlinear limit, which corresponds to accumulated nonlinear phase-shifts around 1 rad. This includes a detailed discussion of the influence of the nonlinear effect self-phase modulation on the output pulse of CPA-systems. An analytical model is presented. Emphasis is placed on the design of novel concepts to control the impact of self-phase modulation. Pulse-shaping is regarded as a powerful tool to accomplish this goal. Novel methods to control the impact of SPM are experimentally demonstrated. The design of these concepts is based on the theoretical findings. Both amplitude- and phase-shaping are studied. Model-based phase-shaping is implemented in a state-of-the-art fiber CPA-system. The influence of the polarization state is also highlighted. Additionally, existing techniques and recent advances are put into context. (orig.)

Central venous pulse pressure analysis using an R-synchronized pressure measurement system.

Science.gov (United States)

Fujita, Yoshihisa; Hayashi, Daisuke; Wada, Shinya; Yoshioka, Naoki; Yasukawa, Takeshi; Pestel, Gunther

2006-12-01

The information derived from central venous catheters is underused. We developed an EKG-R synchronization and averaging system to obtained distinct CVP waveforms and analyzed components of these. Twenty-five paralyzed surgical patients undergoing CVP monitoring under mechanical ventilation were studied. CVP and EKG signals were analyzed employing our system, the mean CVP and CVP at end-diastole during expiration were compared, and CVP waveform components were measured using this system. CVP waveforms were clearly visualized in all patients. They showed the a peak to be 1.8+/- 0.7 mmHg, which was the highest of three peaks, and the x trough to be lower than the y trough (-1.6+/- 0.7 mmHg and -0.9+/- 0.5 mmHg, respectively), with a mean pulse pressure of 3.4 mmHg. The difference between the mean CVP and CVP at end-diastole during expiration was 0.58+/- 0.81 mmHg. The mean CVP can be used as an index of right ventricular preload in patients under mechanical ventilation with regular sinus rhythm. Our newly developed system is useful for clinical monitoring and for education in circulatory physiology.

High voltage pulse system for the streamer chamber supply of the GIBS spectrometer

International Nuclear Information System (INIS)

Aksinenko, V.D.; Glagoleva, N.S.; Dement'ev, E.A.; Kaminskij, N.I.; Matyushin, A.T.; Matyushin, V.T.; Rozhnyatovskaya, S.A.; Ryakhovskij, V.N.; Nurgozhin, N.N.; Khusainov, E.K.

1987-01-01

Results of development and testing of high voltage pulse system HVPS for the streamer chamber supply of the GIBS spectrometer are presented. HVPS consists of the following basic blocks: nanosecond pulse high voltage generator, high voltage charging supply, trigger generator, chamber parameter control devices, gas-oil vacuuming supply systems, auxiliary and fire-prevention devices. The system blocks are described. Experimental results of HVPC testing are presented. HVPC provides a reliable (10 5 operations) of streamer chamber supply with high voltage pulse parameters: amplitude - 500 kV, amplitude instability (0.5-1.5)%, pulse duration - 12 ns, delay time - 500 ns, delay instability (2.5-5)%, mean frequency of output a signals - 0.1 Hz

High current transistor pulse generator

International Nuclear Information System (INIS)

Nesterov, V.; Cassel, R.

1991-05-01

A solid state pulse generator capable of delivering high current trapezoidally shaped pulses into an inductive load has been developed at SLAC. Energy stored in the capacitor bank of the pulse generator is switched to the load through a pair of Darlington transistors. A combination of diodes and Darlington transistors is used to obtain trapezoidal or triangular shaped current pulses into an inductive load and to recover the remaining energy in the same capacitor bank without reversing capacitor voltage. The transistors work in the switch mode, and the power losses are low. The rack mounted pulse generators presently used at SLAC contain a 660 microfarad storage capacitor bank and can deliver 400 amps at 800 volts into inductive loads up to 3 mH. The pulse generators are used in several different power systems, including pulse to pulse bipolar power supplies and in application with current pulses distributed into different inductive loads. The current amplitude and discharge time are controlled by the central computer system through a specially developed multichannel controller. Several years of operation with the pulse generators have proven their consistent performance and reliability. 8 figs

Pulsed high energy synthesis of fine metal powders

Science.gov (United States)

Witherspoon, F. Douglas (Inventor); Massey, Dennis W. (Inventor)

1999-01-01

Repetitively pulsed plasma jets generated by a capillary arc discharge at high stagnation pressure (>15,000 psi) and high temperature (>10,000 K) are utilized to produce 0.1-10 .mu.m sized metal powders and decrease cost of production. The plasma jets impact and atomize melt materials to form the fine powders. The melt can originate from a conventional melt stream or from a pulsed arc between two electrodes. Gas streams used in conventional gas atomization are replaced with much higher momentum flux plasma jets. Delivering strong incident shocks aids in primary disintegration of the molten material. A series of short duration, high pressure plasma pulses fragment the molten material. The pulses introduce sharp velocity gradients in the molten material which disintegrates into fine particles. The plasma pulses have peak pressures of approximately one kilobar. The high pressures improve the efficiency of disintegration. High gas flow velocities and pressures are achieved without reduction in gas density. Repetitively pulsed plasma jets will produce powders with lower mean size and narrower size distribution than conventional atomization techniques.

A Novel Transcranial Magnetic Stimulator Inducing Near Rectangular Pulses with Controllable Pulse Width (cTMS)

Science.gov (United States)

Jalinous, Reza; Lisanby, Sarah H.

2013-01-01

A novel transcranial magnetic stimulation (TMS) device with controllable pulse width (PW) and near rectangular pulse shape (cTMS) is described. The cTMS device uses an insulated gate bipolar transistor (IGBT) with appropriate snubbers to switch coil currents up to 7 kA, enabling PW control from 5 μs to over 100 μs. The near-rectangular induced electric field pulses use 22–34% less energy and generate 67–72% less coil heating compared to matched conventional cosine pulses. CTMS is used to stimulate rhesus monkey motor cortex in vivo with PWs of 20 to 100 μs, demonstrating the expected decrease of threshold pulse amplitude with increasing PW. The technological solutions used in the cTMS prototype can expand functionality, and reduce power consumption and coil heating in TMS, enhancing its research and therapeutic applications. PMID:18232369

Metabolic and respiratory costs of increasing song amplitude in zebra finches.

Directory of Open Access Journals (Sweden)

Sue Anne Zollinger

Full Text Available Bird song is a widely used model in the study of animal communication and sexual selection, and several song features have been shown to reflect the quality of the singer. Recent studies have demonstrated that song amplitude may be an honest signal of current condition in males and that females prefer high amplitude songs. In addition, birds raise the amplitude of their songs to communicate in noisy environments. Although it is generally assumed that louder song should be more costly to produce, there has been little empirical evidence to support this assumption. We tested the assumption by measuring oxygen consumption and respiratory patterns in adult male zebra finches (Taeniopygia guttata singing at different amplitudes in different background noise conditions. As background noise levels increased, birds significantly increased the sound pressure level of their songs. We found that louder songs required significantly greater subsyringeal air sac pressure than quieter songs. Though increased pressure is probably achieved by increasing respiratory muscle activity, these increases did not correlate with measurable increases in oxygen consumption. In addition, we found that oxygen consumption increased in higher background noise, independent of singing behaviour. This observation supports previous research in mammals showing that high levels of environmental noise can induce physiological stress responses. While our study did not find that increasing vocal amplitude increased metabolic costs, further research is needed to determine whether there are other non-metabolic costs of singing louder or costs associated with chronic noise exposure.

CAMAC-compatible differential pulse discriminator-counter

International Nuclear Information System (INIS)

Tselikov, I.V.

1988-01-01

A differential pulse discriminator-counter for a Moessbauer spectrometer is described. Input pulses are collected according to the following algorithm; a pulse is admitted into the channel depending on whether or not the preceding pulse fell into the discrimination window. The circuit does not contain delay lines to allow for the delay lines to allow for the delay of the signal from the upper-level discriminator with respect to the signal from the lower-level discriminator due to the finite rise time of the input pulses, which makes it possible to reduce the dead time of the discriminator to the actuation time of the threshold circuits. The pulse count rate is 150 MHz, the input amplitude is +/-3 V, the dead time is 6 nsec, and the delay from input to output is 14 nsec. The unit is CAMAC-compatible

Consumer perception of the use of high-pressure processing and pulsed electric field technologies in food production

DEFF Research Database (Denmark)

Nielsen, Henriette Boel; Sonne, Anne-Mette; Grunert, Klaus G.

2009-01-01

on consumer attitudes towards high-pressure processing (HPP) and pulsed electric field (PEF) processing of food was carried out. In all 97 adults between 20 and 71 years of age participated in 12 focus groups conducted in Slovenia, Hungary, Serbia, Slovakia, Norway and Denmark using a common guideline...

Pulsed magnet for commutation of 15 MeV electron bunches

International Nuclear Information System (INIS)

Zav'yalov, V.V.; Semenov, V.K.

1987-01-01

The ironless magnet, which extracts certain current pulses from the pulsed microtron electron beam, is described. The 1.4 kGs working field is created in the 12 mm gap between two plane coils arranged inside a vacuum chamber. A simple generator of sinusoidal pulses with the 300 A amplitude and 66 μs duration is used for coil power supply. The power consumption is 660 W at the 400 Hz pulse repetition frequency

Plasma wakefields driven by an incoherent combination of laser pulses: a path towards high-average power laser-plasma accelerators

Energy Technology Data Exchange (ETDEWEB)

Benedetti, C.; Schroeder, C.B.; Esarey, E.; Leemans, W.P.

2014-05-01

he wakefield generated in a plasma by incoherently combining a large number of low energy laser pulses (i.e.,without constraining the pulse phases) is studied analytically and by means of fully-self-consistent particle-in-cell simulations. The structure of the wakefield has been characterized and its amplitude compared with the amplitude of the wake generated by a single (coherent) laser pulse. We show that, in spite of the incoherent nature of the wakefield within the volume occupied by the laser pulses, behind this region the structure of the wakefield can be regular with an amplitude comparable or equal to that obtained from a single pulse with the same energy. Wake generation requires that the incoherent structure in the laser energy density produced by the combined pulses exists on a time scale short compared to the plasma period. Incoherent combination of multiple laser pulses may enable a technologically simpler path to high-repetition rate, high-average power laser-plasma accelerators and associated applications.

Flow Glottogram and Subglottal Pressure Relationship in Singers and Untrained Voices.

Science.gov (United States)

Sundberg, Johan

2018-01-01

This article combines results from three earlier investigations of the glottal voice source during phonation at varying degrees of vocal loudness (1) in five classically trained baritone singers (Sundberg et al., 1999), (2) in 15 female and 14 male untrained voices (Sundberg et al., 2005), and (3) in voices rated as hyperfunctional by an expert panel (Millgård et al., 2015). Voice source data were obtained by inverse filtering. Associated subglottal pressures were estimated from oral pressure during the occlusion for the consonant /p/. Five flow glottogram parameters, (1) maximum flow declination rate (MFDR), (2) peak-to-peak pulse amplitude, (3) level difference between the first and the second harmonics of the voice source, (4) closed quotient, and (5) normalized amplitude quotient, were averaged across the singer subjects and related to associated MFDR values. Strong, quantitative relations, expressed as equations, are found between subglottal pressure and MFDR and between MFDR and each of the other flow glottogram parameters. The values for the untrained voices, as well as those for the voices rated as hyperfunctional, deviate systematically from the values derived from the equations. Copyright © 2018 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

An Investigation of Pulse Transit Time as a Non-Invasive Blood Pressure Measurement Method

International Nuclear Information System (INIS)

McCarthy, B M; O'Flynn, B; Mathewson, A

2011-01-01

The objective of this paper is to examine the Pulse Transit Method (PTT) as a non-invasive means to track Blood Pressure over a short period of time. PTT was measured as the time it takes for an ECG R-wave to propagate to the finger, where it is detected by a photoplethysmograph sensor. The PTT method is ideal for continuous 24-hour Blood Pressure Measurement (BPM) since it is both cuff-less and non-invasive and therefore comfortable and unobtrusive for the patient. Other techniques, such as the oscillometric method, have shown to be accurate and reliable but require a cuff for operation, making them unsuitable for long term monitoring. Although a relatively new technique, the PTT method has shown to be able to accurately track blood pressure changes over short periods of time, after which re-calibration is necessary. The purpose of this study is to determine the accuracy of the method.

Flux transfer events at the dayside magnetopause: Transient reconnection or magnetosheath dynamic pressure pulses?

International Nuclear Information System (INIS)

Lockwood, M.

1991-01-01

The suggestion is discussed that characteristic particle and field signatures at the dayside magnetopause, termed flux transfer events, are, in at least some cases, due to transient solar wind and/or magnetosheath dynamic pressure increases, rather than time-dependent magnetic reconnection. It is found that most individual cases of FTEs observed by a single spacecraft can, at least qualitatively, be explained by the pressure pulse model, provided a few rather unsatisfactory features of the predictions are explained in terms of measurement uncertainties. The most notable exceptions to this are some two-regime observations made by two satellites simultaneously, one on either side of the magnetopause. However, this configuration has not been frequently achieved for sufficient time, such observations are rare, and the relevant tests are still not conclusive. The strongest evidence that FTEs are produced by magnetic reconnection is the dependence of their occurence on the north-south component of the interplanetary magnetic field (IMF) or of the magnetosheath field. The pressure pulse model provides an explanation for this dependence in the case of magnetosheath FTEs, but does not apply to magnetosphere FTEs. The only surveys of magnetosphere FTEs have not employed the simultaneous IMF, but have shown that their occurence is strongly dependent on the north-south component of the magnetosheath field, as observed earlier/later on the same magnetopause crossing. This paper employs statistics on the variability of the IMF orientation to investigate the effects of IMF changes between the times of the magnetosheath and FTE observations. It is shown that the previously published results are consistent with magnetospheric FTEs being entirely absent when the magentosheath field is northward

Propagation of complex shaped ultrafast pulses in highly optically dense samples

International Nuclear Information System (INIS)

Davis, J. C.; Fetterman, M. R.; Warren, W. S.; Goswami, D.

2008-01-01

We examine the propagation of shaped (amplitude- and frequency-modulated) ultrafast laser pulses through optically dense rubidium vapor. Pulse reshaping, stimulated emission dynamics, and residual electronic excitation all strongly depend on the laser pulse shape. For example, frequency swept pulses, which produce adiabatic passage in the optically thin limit (independent of the sign of the frequency sweep), behave unexpectedly in optically dense samples. Paraxial Maxwell optical Bloch equations can model our ultrafast pulse propagation results well and provide insight

On the high gain operation of low-pressure microdot gas avalanche chambers

International Nuclear Information System (INIS)

Breskin, A.

1997-01-01

Microdot avalanche chambers (MDOT) equipped with thin semitransparent Cr photocathodes, were characterized with UV photons at low gas pressure. Gains superior to 10 4 were reached with gas multiplication at the dots. In a mode where preamplification in the gas volume precedes the additional dot multiplication, gains superior to 10 6 were measured at 30-60 torr of propane. The fast amplification mechanism results in narrow high amplitude pulses with 2-3 ns rise time, visible with no further electronic amplification means. We present here our preliminary results and briefly discuss potential applications. (orig.)

Effects of oxygen partial pressure on the ferroelectric properties of pulsed laser deposited Ba{sub 0.8}Sr{sub 0.2}TiO{sub 3} thin films

Energy Technology Data Exchange (ETDEWEB)

Silva, J.P.B.; Sekhar, K.C.; Pereira, M.; Gomes, M.J.M. [University of Minho, Centre of Physics, Braga (Portugal); Almeida, A.; Agostinho Moreira, J. [IFIMUP and IN-Institute of Nanoscience and Nanotechnology, Departamento de Fisica e Astronomia, Faculdade de Ciencias da Universidade do Porto, Porto (Portugal)

2013-11-15

The Ba{sub 0.8}Sr{sub 0.2}TiO{sub 3} thin films were grown on the Pt-Si substrate at 700 C by using a pulsed laser deposition technique at different oxygen partial pressure (PO{sub 2}) in the range of 1-20 Pa and their properties were investigated. It is observed that the PO{sub 2} during the deposition plays an important role on the tetragonal distortion ratio, surface morphology, dielectric permittivity, ferroelectric polarization, switching response, and leakage currents of the films. With an increase in PO{sub 2}, the in-plane strain for the BST films changes from tensile to compressive. The films grown at 7.5 Pa show the optimum dielectric and ferroelectric properties and also exhibit the good polarization stability. It is assumed that a reasonable compressive strain, increasing the ionic displacement, and thus promotes the in-plane polarization in the field direction, could improve the dielectric permittivity. The butterfly features of the capacitance-voltage (C-V) characteristics and the bell shape curve in polarization current were attributed to the domain reversal process. The effect of pulse amplitude on the polarization reversal behavior of the BST films grown at PO{sub 2} of 7.5 Pa was studied. The peak value of the polarization current shows exponential dependence on the electric field. (orig.)