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Sample records for publicly exposed potentially

  1. Industrially contaminated areas in Serbia as a potential public health threat to the exposed population

    Directory of Open Access Journals (Sweden)

    Matić Branislava I.

    2017-01-01

    Full Text Available Mining and mineral processing is still a vital source of income in Serbia, due to mineral abundance in copper, lead, zinc, antimony. Copper mining and metal-processing are located in the east: Bor, Veliki Krivelj, Cerovo, Majdanpek. Abandoned sites from antimony mining and processing and secondary lead smelter are at the western border: Zajača, Krupanj, Stolice. Coal mining and power plants are surrounding Belgrade: Obrenovac (2 power plants, Grabovac (plant ash landfill, Kolubara and Kostolac. Main objective is to focus on potential public health hazards from industrial contamination in Serbia. Key public health issue is presence of As and Cd in ambient air PM10 close to industrially contaminated sites due to the fact that ores have high naturally occurring contents of heavy metals and metalloids. Data originate from Serbian Environmental Protection Agency, Mining and Metallurgy Institute Bor, Belgrade Institute of Public Health, as part of continuous measurement of air quality within State network of automatic stations. Concentration of As in PM10 are extremely above the limit value in Bor and Lazarevac, with Cd values slightly increased in Bor. Serbia lacks the legal framework for continuous and institutionalized follow-up of population groups vulnerable to hazardous environmental exposure, although measured concentration indicate urgent need for such activities.

  2. Suicide and the publicly exposed pedophile.

    Science.gov (United States)

    Walter, Garry; Pridmore, Saxby

    2012-10-01

    Current clinical wisdom is that the vast majority of those who complete suicide suffer from a mental disorder. Uncritical adherence to this belief may limit our understanding and restrict the full range of prevention activities. We aimed to examine the public record for accounts of suicide by men who had been, or were about to be, investigated or apprehended for "sex only" child sex offences, with a view to presenting a collection of case histories, and identifying examples of suicide in the apparent absence of mental disorder other than pedophilia. The public record (hard and electronic copy) was examined. Twenty case histories were identified of men with no apparent mental disorder (other than pedophilia) who completed suicide shortly after exposure or threatened public exposure and/or early or potential legal punishment. This evidence strongly suggests that exposure or threatened public exposure of pedophilia and/or early or potential legal punishment creates a predicament, which may lead to completed suicide.

  3. Citizen scientist lepidopterists exposed to potential carcinogens.

    Science.gov (United States)

    Vainio, Petri J; Vahlberg, Tero; Liesivuori, Jyrki

    2016-05-01

    Lepidopterists use substantial volumes of solvents, such as chloroform, 1,1,2,2-tetrachloroethane and xylene, in their traps when collecting faunistic and phenological data. A majority of them are citizen scientists and thus in part not identified by occupational healthcare as being at risk due to solvent handling. We surveyed the extent of solvent use, the frequency and extent of potential exposure and the safety precautions taken in trapping and catch handling by Finnish lepidopterists. Chloroform and 1,1,2,2-tetrachloroethane were the most frequently used anaesthetics. Potential for exposure prevailed during trap maintenance and exploration and catch sorting. Adequate protection against vapours or spills was worn by 17% during trap exploration. Subjects completed a median of 100 trap explorations per season. Dermal or mucosal spills were recorded at a median rate of one spill per ten (chloroform) to 20 (1,1,2,2-tetrachloroethane and xylene) trap explorations. Median annual cumulative durations of 8 and 20 h of exposure to chloroform and 1,1,2,2-tetrachloroethane at levels above odour detection threshold were reported. Subjective adverse findings possibly related solvents had been noticed by 24 (9.8%) lepidopterists. All the events had been mild to moderate. No factor predicting unsafe procedures or adverse reactions was recorded despite thorough statistical testing. Copyright © 2016 Elsevier Ltd. All rights reserved.

  4. Potential contribution of exposed resin to ecosystem emissions of monoterpenes

    Science.gov (United States)

    Eller, Allyson S. D.; Harley, Peter; Monson, Russell K.

    2013-10-01

    Conifers, especially pines, produce and store under pressure monoterpene-laden resin in canals located throughout the plant. When the plants are damaged and resin canals punctured, the resin is exuded and the monoterpenes are released into the atmosphere, a process that has been shown to influence ecosystem-level monoterpene emissions. Less attention has been paid to the small amounts of resin that are exuded from branches, expanding needles, developing pollen cones, and terminal buds in the absence of any damage. The goal of this study was to provide the first estimate of the potential of this naturally-exposed resin to influence emissions of monoterpenes from ponderosa pine (Pinus ponderosa) ecosystems. When resin is first exuded as small spherical beads from undamaged tissues it emits monoterpenes to the atmosphere at a rate that is four orders of magnitude greater than needle tissue with an equivalent exposed surface area and the emissions from exuded beads decline exponentially as the resin dries. We made measurements of resin beads on the branches of ponderosa pine trees in the middle of the growing season and found, on average, 0.15 cm2 of exposed resin bead surface area and 1250 cm2 of total needle surface area per branch tip. If the resin emerged over the course of 10 days, resin emissions would make up 10% of the ecosystem emissions each day. Since we only accounted for exposed resin at a single point in time, this is probably an underestimate of how much total resin is exuded from undamaged pine tissues over the course of a growing season. Our observations, however, reveal the importance of this previously unrecognized source of monoterpenes emitted from pine forests and its potential to influence regional atmospheric chemistry dynamics.

  5. P300 brain potential among workers exposed to organic solvents

    Directory of Open Access Journals (Sweden)

    Bente E. Moen

    2009-10-01

    Full Text Available  SUMMARYThe P300 component of the auditory event-related brain potential was examined in a group of 11workers exposed to low levels of organic solvents in a paint factory and 11 unexposed controls beforeand after 3 weeks of summer vacation. The P300 latency time was found to be prolonged among theexposed workers compared to the reference group before the summer vacation, and to be significantlylonger before the vacation than after in the exposed group.The P300 component was also examined in a group of 85 seamen from chemical tankers, experiencingpeak exposures to organic solvents. They were compared to a reference group of unexposedseamen. Comparing these two groups, no difference was found in the P300 latency time. No relationshipbetween the P300 latency time and exposure was found in a multiple regression analysis, includingthe variables age, alcohol consumption, smoking and cerebral concussions.The study indicates the occurrence of an acute biological effect in the nervous system related toorganic solvent exposure, expressed by prolonged P300 latency time. This was found at very lowexposure levels and should be studied further.

  6. Radon exposed workplaces in Bavarian public water supplies

    International Nuclear Information System (INIS)

    Heinrich, T.; Huebel, K.; Schindlmeier, W.

    1998-01-01

    From April 1996 to July 1996 a radon-screening in 112 Bavarian water supplies was carried out to determine the radon concentration in workplaces. In some regions with granit or gneiss stones as underground a considerable radiation exposure to the employees in public water supplies can be expected. The median of the measured radon concentration in relevant workplaces is found to be 4000 Bq/m 3 in the areas with granite or gneiss. This is approximately the fourfold of the median measured in a reference area with sandstone as underground. In some workplaces radon concentrations of more than 100000 Bq/m 3 can be found. (orig.) [de

  7. Potential radiation dose from eating fish exposed to actinide contamination

    International Nuclear Information System (INIS)

    Emery, R.M.; Klopfer, D.C.; Baker, D.A.; Soldat, J.K.

    1980-01-01

    The purpose of this work is to establish a maximum potential for transporting actinides to man via fish consumption. The study took place in U-Pond, a nuclear waste pond on the Hanford Site. It has concentrations of 238 U, 238 Pu, /sup 239,240/Pu and 241 Am that are approximately three orders of magnitude greater than background levels. Fish living in the pond contain higher actinide concentrations than those observed in fish from any other location. Experiments were performed in U-pond to determine maximum quantities of actinides that could accumulate in fillets and whole bodies of two centrarchid fish species. Doses to hypothetical consumers were then estimated by assuming that actinide behavior in their bodies was similar to that defined for Standard Man by the International Commission on Radiological Protection. Results indicate that highest concentrations occurring in bluegill or bass muscle after more than a year's exposure to the pond would not be sufficient to produce a significant radiation dose to a human consumer, even if he ate 0.5 kg (∼1 lb) of these fillets every day for 70 years. Natural predators (heron or coyote), having lifetime diets of whole fish from U-Pond, would receive less radiation dose from the ingested actinides than from natural background sources. 34 refs., 5 figs., 4 tabs

  8. Potential radiation dose from eating fish exposed to actinide contamination

    International Nuclear Information System (INIS)

    Emery, R.M.; Klopfer, D.C.; Baker, D.A.; Soldat, J.K.

    1981-01-01

    The purpose of this work is to establish a maximum potential for transporting actinides to man via fish consumption. The study took place in U-pond, a nuclear waste pond on the Hanford Site. It has concentrations of 238 U, 238 Pu, sup(239,240)Pu and 241 Am that are approx. 3 orders of magnitude greater than background levels. Fish living in the pond contain higher actinide concentrations than those observed in fish from any other location. Experiments were performed in U-Pond to determine maximum quantities of actinides that could accumulate in fillets and whole bodies of two centrarchid fish species. Doses to hypothetical consumers were then estimated. Results indicate that highest concentrations occurring in bluegill or bass muscle after more than a year's exposure to the pond would not be sufficient to produce a significant radiation dose to a human consumer, even if he ate 0.5 kg (of the order of 1 lb) of these fillets every day for 70 yr. Natural predators (heron or coyote), having lifetime diets of whole fish from U-Pond, would receive less radiation dose from the ingested actinides than from natural background sources. (author)

  9. Occupational Exposure to Antineoplastic Drugs: Identification of Job Categories Potentially Exposed throughout the Hospital Medication System

    Directory of Open Access Journals (Sweden)

    Chun-Yip Hon

    2011-09-01

    Conclusion: We found drug contamination on select surfaces at every stage of the medication system, which indicates the existence of an exposure potential throughout the facility. Our results suggest that a broader range of workers are potentially exposed than has been previously examined. These results will allow us to develop a more inclusive exposure assessment encompassing all healthcare workers that are at risk throughout the hospital medication system.

  10. Potential for comparative public opinion research in public administration

    NARCIS (Netherlands)

    G. Bouckaert (Geert); S.G.J. Van de Walle (Steven); J. K. Kampen (Jarl)

    2005-01-01

    textabstractThe public administration and public services have always taken a marginal place in the political scientists’ behavioural research. Public administration students on the other hand tend to focus on political and administrative elites and institutions, and largely ignored citizens in

  11. First aid for the public exposed to cesium 137 in Goiania

    International Nuclear Information System (INIS)

    Valverde, N.

    1986-01-01

    The criterias for triage and reference to a third-level center of individuals of the public exposed to sup(137)Cs, in Goiania, State of Goias, Brazil, are described. Triage was hindered by the lack of physical dosimeters, the characteristics of the place where the accident took place, the delay between the casualty and its recognition, cultural mishaps together with a sense of possible legal liability, making the delivered information suspicious and a strike affecting the hospital where the patients were admitted, as well as its sponsoring institution, that made laboratory assistance virtually not available. Triage was exclusively based upon the histories, prodomal manifestations and physical findings. (author)

  12. Mortality of workers potentially exposed to organic and inorganic brominated chemicals, DBCP, TRIS, PBB, and DDT

    Energy Technology Data Exchange (ETDEWEB)

    Wong, O; Brocker, W; Davis, H V; Nagle, G S

    1984-02-01

    A historical prospective mortality study was conducted on 3579 white male workers employed between 1935 and 1976 with potential exposures to brominated compounds including 1,2-dibromo-3-chloropropane (DBCP), Tris (2,3-dibromopropyl) phosphate, polybrominated biphenyls (PBB), various organic and inorganic bromides, and DDT. Death certificates were obtained for 541 deaths (94% of all deaths). The mortality experience of the entire cohort and several subcohorts was compared with that of United States white men adjusted for age and calendar time. The comparison statistic was the commonly used standardised mortality ratio (SMR). Historical industrial hygiene data were not available, and the workers were classified by their work areas or departments in order to estimate their potential exposures. Overall mortality for the entire cohort and several subgroups was significantly lower than expected. For the entire cohort, significant mortality deficits were observed in diseases of the circulatory system, non-malignant respiratory disease, and diseases of the digestive system. On the other hand, mortality from diabetes mellitus was significantly raised for the cohort. No significant overall or cause-specific mortality excess was detected among employees potentially exposed to either TRIS or DDT. A significant mortality excess due to diseases of the circulatory system was observed among workers potentially exposed to DBCP. Mortality from testicular cancer was significantly higher than expected among those potentially exposed to other organic bromides. The common potential exposure of those who had died of testicular cancer was methyl bromide. Owing to the lack of accurate historical exposure information and the fact that many workers were potentially exposed to a multitude of chemicals, it is difficult to draw definitive statements on the causations of the observed mortality excesses.

  13. Attention bias in earthquake-exposed survivors: an event-related potential study.

    Science.gov (United States)

    Zhang, Yan; Kong, Fanchang; Han, Li; Najam Ul Hasan, Abbasi; Chen, Hong

    2014-12-01

    The Chinese Wenchuan earthquake, which happened on the 28th of May in 2008, may leave deep invisible scars in individuals. China has a large number of children and adolescents, who tend to be most vulnerable because they are in an early stage of human development and possible post-traumatic psychological distress may have a life-long consequence. Trauma survivors without post-traumatic stress disorder (PTSD) have received little attention in previous studies, especially in event-related potential (ERP) studies. We compared the attention bias to threat stimuli between the earthquake-exposed group and the control group in a masked version of the dot probe task. The target probe presented at the same space location consistent with earthquake-related words was the congruent trial, while in the space location of neutral words was the incongruent trial. Thirteen earthquake-exposed middle school students without PTSD and 13 matched controls were included in this investigation. The earthquake-exposed group showed significantly faster RTs to congruent trials than to incongruent trials. The earthquake-exposed group produced significantly shorter C1 and P1 latencies and larger C1, P1 and P2 amplitudes than the control group. In particular, enhanced P1 amplitude to threat stimuli was observed in the earthquake-exposed group. These findings are in agreement with the prediction that earthquake-exposed survivors have an attention bias to threat stimuli. The traumatic event had a much greater effect on earthquake-exposed survivors even if they showed no PTSD symptoms than individuals in the controls. These results will provide neurobiological evidences for effective intervention and prevention to post-traumatic mental problems. Copyright © 2014 Elsevier B.V. All rights reserved.

  14. Human potential development as a prerequisite of public policy efficiency

    Directory of Open Access Journals (Sweden)

    Polishchuk Iryna Viktorivna

    2014-12-01

    Full Text Available The article analyses the role of the public officers’ human potential for the efficiency of making public policy. It introduces features and criteria of human potential in the context of its development of civil service. The article designates some key directions for the development of human potential of public officers.

  15. Colloids exposed to random potential energy landscapes: From particle number density to particle-potential and particle-particle interactions

    International Nuclear Information System (INIS)

    Bewerunge, Jörg; Capellmann, Ronja F.; Platten, Florian; Egelhaaf, Stefan U.; Sengupta, Ankush; Sengupta, Surajit

    2016-01-01

    Colloidal particles were exposed to a random potential energy landscape that has been created optically via a speckle pattern. The mean particle density as well as the potential roughness, i.e., the disorder strength, were varied. The local probability density of the particles as well as its main characteristics were determined. For the first time, the disorder-averaged pair density correlation function g (1) (r) and an analogue of the Edwards-Anderson order parameter g (2) (r), which quantifies the correlation of the mean local density among disorder realisations, were measured experimentally and shown to be consistent with replica liquid state theory results.

  16. The potential DNA toxic changes among workers exposed to antimony trioxide.

    Science.gov (United States)

    El Shanawany, Safaa; Foda, Nermine; Hashad, Doaa I; Salama, Naglaa; Sobh, Zahraa

    2017-05-01

    Occupational exposure to antimony has gained much interest when specific toxic effects were noticed among workers processing antimony. Thus, the aim of the present work was to investigate the potential DNA oxidative damage occurring among Egyptian workers occupationally exposed to antimony trioxide. The study was conducted on 25 subjects exposed to antimony trioxide while working in the polymerization process of polyester in Misrayon and Polyester Fiber Company, KafrEldawwar, Beheira, Egypt. Urinary antimony levels were assessed using inductive coupled plasma-optical emission spectrometry (ICP-OES) and considered as a biological exposure index. DNA damage and total oxidant capacity (TOC) were assessed using ELISA. DNA damage was detected in the form of increased apurinic/apyrimidinic (AP) sites among antimony trioxide-exposed workers compared to control subjects, but it could not be explained by oxidative mechanisms due to lack of significant correlation between DNA damage and measured TOC. Antimony trioxide might have a genotoxic impact on occupationally exposed workers which could not be attributed to oxidative stress in the studied cases.

  17. Environmental noise-exposed workers: event-related potentials, neuropsychological and mood assessment.

    Science.gov (United States)

    Chiovenda, Paola; Pasqualetti, Patrizio; Zappasodi, Filippo; Ercolani, Matilde; Milazzo, Daniele; Tomei, Gianfranco; Capozzella, Assuntina; Tomei, Francesco; Rossini, Paolo M; Tecchio, Franca

    2007-09-01

    Prolonged environmental noise exposure can induce pathogenic effects on various physical and psychosocial responses. The first aim of this study was to investigate whether long-term occupational noise exposure could affect neurophysiological, neuropsychological and emotional statuses, with particular respect to attention and working memory. The second aim was to evaluate the effects on the tactile P300 of a specific stressor (background traffic noise) vs a non-specific stress inductor (Stroop test). The comparison between a group of noise-exposed workers (traffic police officers), and a control group (office employees) did not show marked differences in cognitive and emotional profiles. The amplitude of the baseline cognitive potential (P300), recorded during a tactile (electric) discrimination task, resulted higher in noise-exposed workers than in controls, and this enhancement was associated with a lower level of trait anxiety and better mood profiles. Moreover, we found a wider P300 amplitude reduction in traffic police officers than in controls, under noisy conditions due to traffic. The effect of the Stroop test as a stress inductor was negligible and similar in the two groups. The wider amplitude of the non-auditory P300 in traffic police officers in the baseline condition could be a sign of cross-modal cerebral plasticity enhancing attentive processes in the 'stress-free' sensory channel. In addition, noise-exposed workers presented a higher cerebral sensitivity to stress selectively when they were exposed to the habitual environmental stressor.

  18. [Clinical treatment adherence of health care workers and students exposed to potentially infectious biological material].

    Science.gov (United States)

    Almeida, Maria Cristina Mendes de; Canini, Silvia Rita Marin da Silva; Reis, Renata Karina; Toffano, Silmara Elaine Malaguti; Pereira, Fernanda Maria Vieira; Gir, Elucir

    2015-04-01

    To assess adherence to clinical appointments by health care workers (HCW) and students who suffered accidents with potentially infectious biological material. A retrospective cross-sectional study that assessed clinical records of accidents involving biological material between 2005 and 2010 in a specialized unit. A total of 461 individuals exposed to biological material were treated, of which 389 (84.4%) were HCWs and 72 (15.6%) students. Of the 461 exposed individuals, 307 (66.6%) attended a follow-up appointment. Individuals who had suffered an accident with a known source patient were 29 times more likely to show up to their scheduled follow-up appointments (OR: 29.98; CI95%: 16.09-55.83). The predictor in both univariate and multivariate analyses for adherence to clinical follow-up appointment was having a known source patient with nonreactive serology for the human immunodeficiency virus and/or hepatitis B and C.

  19. MELATONIN: POTENTIAL UTILITY FOR IMPROVING PUBLIC HEALTH

    Directory of Open Access Journals (Sweden)

    Russel J REITER; Fatih GULTEKIN; Luis J FLORES; Ma Pilar TERRON; Dun-Xian TAN

    2006-04-01

    Full Text Available This review summarizes the beneficial actions of melatonin in various experimental conditions/diseases and identifies where the use of melatonin may be helpful in improving public health. The nightly use of melatonin supplements by humans often improves their sleep and helps correct the circadian dyssynchronization associated with “jet lag”. Additionally, melatonin has been found effective in curtailing the growth of a variety of experimental cancers. Mechanistically, this is achieved by melatonin’s ability to limit fatty acid uptake, especially linoleic acid, by tumor cells. Fatty acids are growth factors for many tumors. Additionally, melatonin inhibits the elevated telomerase activity of tumor cells thus making them more fragile and vulnerable to chemotherapies. Melatonin also may inhibit angiogenesis in tumors by suppressing endothelin-1 production and the indole interferes with the stimulatory action of steroids on hormone-responsive tumors. As an ubiquitously-acting antioxidant, melatonin reduces cardiac damage during ischemia/reperfusion (I/R injury (heart attack and during I/R to the brain (stroke. Melatonin also limits the toxicity of amyloid  peptide and of neurofibrillary tangles, two of the cardinal signs of Alzheimer’s disease. Collectively, these data suggest supplementation with melatonin, whose endogenous levels decrease with age, may improve the quality of life in the aged and, as a consequence, be beneficial for public health generally. [TAF Prev Med Bull 2006; 5(2.000: 131-158

  20. Clinical treatment adherence of health care workers and students exposed to potentially infectious biological material

    Directory of Open Access Journals (Sweden)

    Maria Cristina Mendes de Almeida

    2015-04-01

    Full Text Available OBJECTIVE To assess adherence to clinical appointments by health care workers (HCW and students who suffered accidents with potentially infectious biological material. METHOD A retrospective cross-sectional study that assessed clinical records of accidents involving biological material between 2005 and 2010 in a specialized unit. RESULTS A total of 461 individuals exposed to biological material were treated, of which 389 (84.4% were HCWs and 72 (15.6% students. Of the 461 exposed individuals, 307 (66.6% attended a follow-up appointment. Individuals who had suffered an accident with a known source patient were 29 times more likely to show up to their scheduled follow-up appointments (OR: 29.98; CI95%: 16.09-55.83. CONCLUSION The predictor in both univariate and multivariate analyses for adherence to clinical follow-up appointment was having a known source patient with nonreactive serology for the human immunodeficiency virus and/or hepatitis B and C.

  1. Spatial Interaction Modeling to Identify Potentially Exposed Populations during RDD or IND Terrorism Incidents

    International Nuclear Information System (INIS)

    Regens, J.L.; Gunter, J.T.; Gupta, S.

    2009-01-01

    Homeland Security Presidential Directive no.5 (HSPD-5) Management of Domestic Incidents and Department of Homeland Security (DHS) Planning Guidance for Protection and Recovery Following Radiological Dispersal Device (RDD) and Improvised Nuclear Device (IND) Incidents underscore the need to delineate radiological emergency guidance applicable to remedial action and recovery following an RDD or IND incident. Rapid delineation of the population potentially exposed to ionizing radiation from fallout during terrorist incidents involving RDDs or low-yield nuclear devices (≤ 20 KT) is necessary for effective medical response and incident management as part of the recovery process. This paper illustrates the application of spatial interaction models to allocate population data for a representative U.S. urban area (≅1.3M people; 1,612.27 km 2 area) at a geographical scale relevant for accurately estimating risk given dose concentrations. Estimated total dose equivalents (TEDE) are calculated for isopleths moving away from the detonation point for typical release scenarios. Population is estimated within the TEDE zones using Euclidean distances between zip code polygon centroids generated in ArcGIS version 9.1 with distance decay determined by regression analysis to apportion origin-destination pairs to a population count and density matrix on a spatial basis for daytime and night-time release scenarios. (authors)

  2. White Paper on Potential Hazards Associated with Contaminated Cheesecloth Exposed to Nitric Acid Solutions

    Energy Technology Data Exchange (ETDEWEB)

    Hypes, Philip A. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-09-20

    This white paper addresses the potential hazards associated with waste cheesecloth that has been exposed to nitric acid solutions. This issue was highlighted by the cleanup of a 100 ml leak of aqueous nitric acid solution containing Heat Source (HS) plutonium on 21 June 2016. Nitration of cellulosic material is a well-understood process due to industrial/military applications of the resulting material. Within the Department of Energy complex, nitric acids have been used extensively, as have cellulosic wipes. If cellulosic materials are nitrated, the cellulosic material can become ignitable and in extreme cases, reactive. We have chemistry knowledge and operating experience to support the conclusion that all current wastes are safe and compliant. There are technical questions worthy of further experimental evaluation. An extent of condition evaluation has been conducted back to 2004. During this time period there have been interruptions in the authorization to use cellulosic wipes in PF-4. Limited use has been authorized since 2007 (for purposes other than spill cleanup), so our extent of condition includes the entire current span of use. Our evaluation shows that there is no indication that process spills involving high molarity nitric acid were cleaned up with cheesecloth since 2007. The materials generated in the 21 June leak will be managed in a safe manner compliant with all applicable requirements.

  3. Surviving and Thriving—Shifting the Public Health Response to HIV-Exposed Uninfected Children: Report of the 3rd HIV-Exposed Uninfected Child Workshop

    Directory of Open Access Journals (Sweden)

    Amy L. Slogrove

    2018-05-01

    Full Text Available Great gains were achieved with the introduction of the United Nations' Millennium Development Goals, including improved child survival. Transition to the Sustainable Development Goals (SDGs focused on surviving, thriving, and transforming, representing an important shift to a broader public health goal, the achievement of which holds the promise of longer-term individual and societal benefits. A similar shift is needed with respect to outcomes for infants born to women living with HIV (WLHIV. Programming to prevent vertical HIV transmission has been successful in increasingly achieving a goal of HIV-free survival for infants born to WLHIV. Unfortunately, HIV-exposed uninfected (HEU children are not achieving comparable health and developmental outcomes compared with children born to HIV-uninfected women under similar socioeconomic circumstances. The 3rd HEU Child Workshop, held as a satellite session of the International AIDS Society's 9th IAS Conference in Paris in July 2017, provided a venue to discuss HEU child health and development disparities. A summary of the Workshop proceedings follows, providing current scientific findings, emphasizing the gap in systems for long-term monitoring, and highlighting the public health need to establish a strategic plan to better quantify the short and longer-term health and developmental outcomes of HEU children.

  4. Genetic damage in human cells exposed to non-ionizing radiofrequency fields: a meta-analysis of the data from 88 publications (1990-2011).

    Science.gov (United States)

    Vijayalaxmi; Prihoda, Thomas J

    2012-12-12

    Based on the 'limited' evidence suggesting an association between exposure to radiofrequency fields (RF) emitted from mobile phones and two types of brain cancer, glioma and acoustic neuroma, the International Agency for Research on Cancer has classified RF as 'possibly carcinogenic to humans' in group 2B. In view of this classification and the positive correlation between increased genetic damage and carcinogenesis, a meta-analysis was conducted to determine whether a significant increase in genetic damage in human cells exposed to RF provides a potential mechanism for its carcinogenic potential. The extent of genetic damage in human cells, assessed from various end-points, viz., single-/double-strand breaks in the DNA, incidence of chromosomal aberrations, micronuclei and sister chromatid exchanges, reported in a total of 88 peer-reviewed scientific publications during 1990-2011 was considered in the meta-analysis. Among the several variables in the experimental protocols used, the influence of five specific variables related to RF exposure characteristics was investigated: (i) frequency, (ii) specific absorption rate, (iii) exposure as continuous wave, pulsed wave and occupationally exposed/mobile phone users, (iv) duration of exposure, and (v) different cell types. The data indicated the following. (1) The magnitude of difference between RF-exposed and sham-/un-exposed controls was small with some exceptions. (2) In certain RF exposure conditions there was a statistically significant increase in genotoxicity assessed from some end-points: the effect was observed in studies with small sample size and was largely influenced by publication bias. Studies conducted within the generally recommended RF exposure guidelines showed a smaller effect. (3) The multiple regression analyses and heterogeneity goodness of fit data indicated that factors other than the above five variables as well as the quality of publications have contributed to the overall results. (4) More

  5. Bovine coronavirus in naturally and experimentally exposed calves; viral shedding and the potential for transmission.

    Science.gov (United States)

    Oma, Veslemøy Sunniva; Tråvén, Madeleine; Alenius, Stefan; Myrmel, Mette; Stokstad, Maria

    2016-06-13

    Bovine coronavirus (BCoV) is a widely distributed pathogen, causing disease and economic losses in the cattle industry worldwide. Prevention of virus spread is impeded by a lack of basic knowledge concerning viral shedding and transmission potential in individual animals. The aims of the study were to investigate the duration and quantity of BCoV shedding in feces and nasal secretions related to clinical signs, the presence of virus in blood and tissues and to test the hypothesis that seropositive calves are not infectious to naïve in-contact calves three weeks after BCoV infection. A live animal experiment was conducted, with direct contact between animal groups for 24 h as challenge procedure. Four naïve calves were commingled with a group of six naturally infected calves and sequentially euthanized. Two naïve sentinel calves were commingled with the experimentally exposed group three weeks after exposure. Nasal swabs, feces, blood and tissue samples were analyzed for viral RNA by RT-qPCR, and virus isolation was performed on nasal swabs. Serum was analyzed for BCoV antibodies. The calves showed mild general signs, and the most prominent signs were from the respiratory system. The overall clinical score corresponded well with the shedding of viral RNA the first three weeks after challenge. General depression and cough were the signs that correlated best with shedding of BCoV RNA, while peak respiratory rate and peak rectal temperature appeared more than a week later than the peak shedding. Nasal shedding preceded fecal shedding, and the calves had detectable amounts of viral RNA intermittently in feces through day 35 and in nasal secretions through day 28, however virus isolation was unsuccessful from day six and day 18 from the two calves investigated. Viral RNA was not detected in blood, but was found in lymphatic tissue through day 42 after challenge. Although the calves were shedding BCoV RNA 21 days after infection the sentinel animals were not infected

  6. A Public Relations Nightmare: ACLU Class Action Lawsuit Exposes Inaccurate and Inequitable High School Graduation Rates

    Science.gov (United States)

    Watson, Terri N.; Brown, Kathleen M.

    2010-01-01

    Florida's decision to equate a GED to a high school diploma undermines the attempt of No Child Left Behind to close the achievement gap, while infringing on the public's trust. Public trust fosters a culture of systemic equity and social justice, which are necessary for academic excellence (Byrk & Schneider, 2003). Florida's code of ethics for…

  7. Using science centers to expose the general public to the microworld

    Energy Technology Data Exchange (ETDEWEB)

    Malamud, E. [Fermi National Accelerator Lab., Batavia, IL (United States)]|[Science and Technology Interactive Center, Aurora, IL (United States)

    1994-08-01

    Despite the remarkable progress in the past decades in understanding our Universe, we particle physicists have failed to communicate the wonder, excitement, and beauty of these discoveries to the general public. I am sure all agree there is a need, if our support from public funds is to continue at anywhere approximating the present level, for us collectively to educate and inform the general public of what we are doing and why. Informal science education and especially science and technology centers can play an important role in efforts to raise public awareness of particle physics in particular and of basic research in general. Science Centers are a natural avenue for particle physicists to use to communicate with and gain support from the general public.

  8. Using science centers to expose the general public to the microworld

    International Nuclear Information System (INIS)

    Malamud, E.

    1994-08-01

    Despite the remarkable progress in the past decades in understanding our Universe, we particle physicists have failed to communicate the wonder, excitement, and beauty of these discoveries to the general public. I am sure all agree there is a need, if our support from public funds is to continue at anywhere approximating the present level, for us collectively to educate and inform the general public of what we are doing and why. Informal science education and especially science and technology centers can play an important role in efforts to raise public awareness of particle physics in particular and of basic research in general. Science Centers are a natural avenue for particle physicists to use to communicate with and gain support from the general public

  9. Public health informatics in India: the potential and the challenges.

    Science.gov (United States)

    Athavale, A V; Zodpey, Sanjay P

    2010-01-01

    Public health informatics is emerging as a new and distinct specialty area in the global scenario within the broader discipline of health informatics. The potential role of informatics in reducing health disparities in underserved populations has been identified by a number of reports from all over the world. The article discusses the scope, the limitations, and future perspective of this novice discipline in context to India. It also highlights information and technology related tools namely Geographical Information Systems, Telemedicine and Electronic Medical Record/Electronic Health Record. India needs to leverage its "technology" oriented growth until now (e.g., few satellite-based telemedicine projects, etc.) simultaneously toward development of "information"-based public health informatics systems in future. Under the rapidly evolving scenario of global public health, the future of the public health governance and population health in India would depend upon building and integrating the comprehensive and responsive domain of public health informatics.

  10. Exposing K-12 Filipino Achievement Gaps and Opportunities in Hawaii Public Schools

    Science.gov (United States)

    Halagao, Patricia Espiritu

    2016-01-01

    As a multicultural teacher educator, the author is always interested in teachers' perceptions of who their students are and where they come from. The purpose of this study is to examine the academic experiences of one of the largest ethnic groups in Hawai'i's public school system: Filipinos. Filipinos have long been an under-examined group in…

  11. Retrospective genetic study of germinative mutations in Str loci of individuals potentially exposed to ionizing radiation

    International Nuclear Information System (INIS)

    Costa, Emilia Oliveira Alves

    2010-01-01

    The Brazilian radiological accident that occurred in 1987, in Goiania, it was a terrible radiation episode. As a consequence, hundreds of people were contaminated due to the Cesium-137 radiation. Recently, many studies had shown that genome instabilities, such as, mutations, chromosomal aberrations, micronuclei formation and micro satellite instability and a delay on cellular death are usually reported on mammal cells exposed to ionizing radiation, being considered as a manly risk to humans. Mutations can be spontaneous, and the occurrence is dependent on the organism, or, induced, being associated to mutagenic exposition. Ionizing radiations are an example of physical and mutagenic agents that could harm the cell repair and could cause the development of many types of cancer. The evaluation of the biological effects of the ionizing radiation, in somatic and germ line cells, with a consequent determination of the radio-induced mutations, it is extremely important to estimate the genetic risks, manly in population exposed to radiation. The analyses of repetitive DNA sequences have been demonstrated that such sequences are prone to high rates of spontaneous mutations. The minisatellites and microsatellites have been used to demonstrate the induction of germ line mutation rates on mouse, humans, among others organisms. The aim of the present study was to analyze the frequency of microsatellite alterations to determine the mutation rates occurred in germ cells of the parents exposed to the ionizing radiation of the Cesium-137. The studied group was constitute of 10 families of individuals accidentally exposed to Cesium-137 and by the control group constituted by 645 healthy individuals who carried out paternity tests on 2009. We found only one mutation of paternal origin in the D8S1179 locus on the exposed group, being the mutation rate of 0.002. In the control group, we found 01 mutation on D16S539 loei and on D3S1358; 02 mutations on Penta E loeus; 04 mutations on D

  12. Potential Ecological Effects of Contaminants in the Exposed Par Pond Sediments

    International Nuclear Information System (INIS)

    Paller, M.H.; Wike, L.D.

    1996-08-01

    Sediment and small mammal samples were collected from the exposed sediments of Par Pond in early 1995, shortly before the reservoir was refilled after a 4-year drawdown. Sampling was confined to elevations between 58 and 61 meters (190 and 200 feet) above mean sea level, which includes the sediments likely to be exposed if the Par Pond water level is permitted to fluctuate naturally. Both soil and small mammal samples were analyzed for a number of radionuclides and metals. Some of the soil samples were also analyzed for organic contaminants. The objective of the study was to determine if contaminant levels in the Par Pond sediments were high enough to cause deleterious ecological effects

  13. Informal public transport driver behaviour and regulatory policy linkage: An expose

    Directory of Open Access Journals (Sweden)

    Smart Dumba

    2017-09-01

    Full Text Available Background: Literature on the negative socio-economic and environmental externalities generated by informal public transport (IPT in developing countries is vast, vibrant and growing fast. These externalities include but are not limited to noise, air and land pollution, accidents and, more importantly, a source of congestion (human and vehicular because of poor driver behaviour. In this article, the research does not seek to reinstate these, but rather, it argues that poor driver behaviour is a dependent variable to some regulatory policy stimuli. Yet, an extensive literature survey has shown that the driver behaviour and urban transport regulation linkage remain little explored. Objective: The purpose of this article was to unpack the relationship between informal public transport driver behaviour and the prevailing regulatory framework. Method: Based on a case study of Harare, Zimbabwe, the researcher adopted a mixed-methods paradigm and interrogated the prevailing urban public transport regulatory regimes and applied professional judgement, oral interviews backed by some quantitative data and relate these to obtaining IPT driver behavioural characteristics. Results: Poor driver behaviour exhibited by IPT were generated, exacerbated and or eased by the prevailing regulatory policy. This is well depicted through an IPT driver behaviour and regulation loop reinforcing diagram. Conclusion: Following this argument, the article cautions policy makers and urban managers alike that direct approaches and interventions when trying to regulate IPT poor driver behaviour and its secondary negative effects will be futile as long as the regulatory policy remains the same. Failure to recognise and connect the dots between IPT driver behaviour and policy partly explains why globally, the IPT sector has proved difficult in prohibiting, restructuring or even formalising it.

  14. The empowerment potential of public sector software (PSS

    Directory of Open Access Journals (Sweden)

    Pradip Ninan Thomas

    2012-03-01

    Full Text Available Investigations into the potential for public sector software (PSS to empower citizens are at a very nascent stage. This article explores the theoretical basis for, and practical advantages of, PSS, in the making of an informed and pro-active citizenry. Using the example of the emerging PSS movement in India and in particular the ICT literacy movement in Kerala, South India, it argues, that access to and use of software based on the principles of free and open source has the potential to contribute to an empowered citizenry. However the very concept of PSS is contested by major private software companies given that they stand to lose from public investments that are based on open standards. The article argues that PSS can contribute to the making of an ‘information commons’ and that the need of the hour is for innovative and creative solutions to the information deficits faced by communities in India and elsewhere.

  15. Management of children exposed to Mycobacterium tuberculosis: a public health evaluation in West Java, Indonesia.

    Science.gov (United States)

    Rutherford, Merrin E; Ruslami, Rovina; Anselmo, Melissa; Alisjahbana, Bachti; Yulianti, Neti; Sampurno, Hedy; van Crevel, Reinout; Hill, Philip C

    2013-12-01

    To investigate qualitatively and quantitatively the performance of a programme for managing the child contacts of adult tuberculosis patients in Indonesia. A public health evaluation framework was used to assess gaps in a child contact management programme at a lung clinic. Targets for programme performance indicators were derived from established programme indicator targets, the scientific literature and expert opinion. Compliance with tuberculosis screening, the initiation of isoniazid preventive therapy in children younger than 5 years, the accuracy of tuberculosis diagnosis and adherence to preventive therapy were assessed in 755 child contacts in two cohorts. In addition, 22 primary caregivers and 34 clinic staff were interviewed to evaluate knowledge and acceptance of child contact management. The cost to caregivers was recorded. Gaps between observed and target indicator values were quantified. THE GAPS BETWEEN OBSERVED AND TARGET PERFORMANCE INDICATORS WERE: 82% for screening compliance; 64 to 100% for diagnostic accuracy, 50% for the initiation of preventive therapy, 54% for adherence to therapy and 50% for costs. Many staff did not have adequate knowledge of, or an appropriate attitude towards, child contact management, especially regarding isoniazid preventive therapy. Caregivers had good knowledge of screening but not of preventive therapy and had difficulty travelling to the clinic and paying costs. The study identified widespread gaps in the performance of a child contact management system in Indonesia, all of which appear amenable to intervention. The public health evaluation framework used could be applied in other settings where child contact management is failing.

  16. Overcoming negative tendencies concerning public attitude to potentially dangerous technologies

    International Nuclear Information System (INIS)

    Barinov, A.; Shmelev, S.

    1995-01-01

    The Moscow Scientific industrial Association RADON is an enterprise with potentially dangerous technology. RADON fulfils the collection, transportation, treatment and disposal of radioactive waste from Moscow region. The inhabitants of this region consider it, and that is true, to be essentially dangerous. We understood, that it is necessary to change the situation and give the public the true information about RADON's activity. For this purpose 4 years ago we developed a new Department, the Department or External Relations

  17. Public health intelligence and the detection of potential pandemics.

    Science.gov (United States)

    French, Martin; Mykhalovskiy, Eric

    2013-02-01

    This article considers contemporary developments in public health intelligence (PHI), especially their focus on health events of pandemic potential. It argues that the sociological study of PHI can yield important insights for the sociology of pandemics. PHI aims to detect health events as (or even before) they unfold. Whilst its apparatuses envelope traditional public health activities, such as epidemiological surveillance, they increasingly extend to non-traditional public health activities such as data-mining in electronically mediated social networks. With a focus on non-traditional PHI activities, the article first situates the study of PHI in relation to the sociology of public health. It then discusses the conceptualisation and actualisation of pandemics, reflecting on how public health professionals and organisations must equip themselves with diverse allies in order to realise the claims they make about pandemic phenomena. Finally, using the analytic tools of actor-network theory, sites for future empirical research that can contribute to the sociology of pandemics are suggested. © 2012 The Authors. Sociology of Health & Illness © 2012 Foundation for the Sociology of Health & Illness/Blackwell Publishing Ltd.

  18. Meet the Maximally Exposed Member of the Public: The Service Station Attendant for Spent Nuclear Fuel Going to Yucca Mountain

    International Nuclear Information System (INIS)

    Collins, H. E.; Gathers, R.; Halstead, R. J.

    2002-01-01

    According to the 1999 Draft Environmental Impact Statement (DEIS) for the proposed Yucca Mountain repository site, members of the public along transportation routes by which spent nuclear fuel (SNF) and high-level radioactive waste (HLW) is shipped will receive annual radiation doses less than 100 mrem/yr, the international (ICRP) and national (Department of Energy, Nuclear Regulatory Commission) radiation limit for members of the public. For the ''Mostly Truck'' national transportation scenario, the DEIS specifically concludes that the maximally exposed member of the public, a service station attendant along the primary shipping route will receive no more than 100 mrem/yr, or 2.4 rem over 24 years. Based on the assumptions in the DEIS scenarios, however, it is highly likely that service station attendants along shipping routes will be called upon to fuel and service the rigs carrying SNF and HLW to Yucca Mountain. After reevaluating the DEIS, and making realistic alternative assumptions where necessary, the authors conclude that these attendants are likely to receive substantially more than 100 mrem/yr external dose, and perhaps several times that dose (up to 500 mrem/yr), unless mitigating measures are adopted. This is particularly true in Western states where refueling opportunities are limited, and the distances between fuel sources in rural areas may be up to 100 miles

  19. Development of auditory event-related potentials in infants prenatally exposed to methadone.

    Science.gov (United States)

    Paul, Jonathan A; Logan, Beth A; Krishnan, Ramesh; Heller, Nicole A; Morrison, Deborah G; Pritham, Ursula A; Tisher, Paul W; Troese, Marcia; Brown, Mark S; Hayes, Marie J

    2014-07-01

    Developmental features of the P2 auditory ERP in a change detection paradigm were examined in infants prenatally exposed to methadone. Opiate dependent pregnant women maintained on methadone replacement therapy were recruited during pregnancy (N = 60). Current and historical alcohol and substance use, SES, and psychiatric status were assessed with a maternal interview during the third trimester. Medical records were used to collect information regarding maternal medications, monthly urinalysis, and breathalyzer to confirm comorbid drug and alcohol exposures. Between birth and 4 months infant ERP change detection performance was evaluated on one occasion with the oddball paradigm (.2 probability oddball) using pure-tone stimuli (standard = 1 kHz and oddball = 2 kHz frequency) at midline electrode sites, Fz, Cz, Pz. Infant groups were examined in the following developmental windows: 4-15, 16-32, or 33-120 days PNA. Older groups showed increased P2 amplitude at Fz and effective change detection performance at P2 not seen in the newborn group. Developmental maturation of amplitude and stimulus discrimination for P2 has been reported in developing infants at all of the ages tested and data reported here in the older infants are consistent with typical development. However, it has been previously reported that the P2 amplitude difference is detectable in neonates; therefore, absence of a difference in P2 amplitude between stimuli in the 4-15 days group may represent impaired ERP performance by neonatal abstinence syndrome or prenatal methadone exposure. © 2013 Wiley Periodicals, Inc.

  20. 75 FR 43184 - Transport of Laboratory Personnel Potentially Exposed to Infectious Agents From Fort Detrick...

    Science.gov (United States)

    2010-07-23

    .... This facility will be fully staffed with experts in infectious diseases who will be conducting applied... diseases who will be conducting applied research. This unit could easily be made available to laboratory.... Ecology The Selected Alternative would not be expected to have the potential to significantly impact the...

  1. Exposing Students to the Potential and Risks of Stakeholder Engagement when Teaching Sustainability: A Classroom Exercise

    Science.gov (United States)

    Collins, Eva; Kearins, Kate

    2007-01-01

    In-class, stakeholder negotiation exercises are proposed as a means of students experiencing and reflecting critically on the potential and the risks of an increasingly popular mechanism for advancing sustainability--stakeholder engagement. This article reviews the theoretical framework for stakeholder engagement and for an issue-based rather than…

  2. Residential proximity to abandoned uranium mines and serum inflammatory potential in chronically exposed Navajo communities.

    Science.gov (United States)

    Harmon, Molly E; Lewis, Johnnye; Miller, Curtis; Hoover, Joseph; Ali, Abdul-Mehdi S; Shuey, Chris; Cajero, Miranda; Lucas, Selita; Zychowski, Katherine; Pacheco, Bernadette; Erdei, Esther; Ramone, Sandy; Nez, Teddy; Gonzales, Melissa; Campen, Matthew J

    2017-07-01

    Members of the Navajo Nation, who possess a high prevalence of cardiometabolic disease, reside near hundreds of local abandoned uranium mines (AUM), which contribute uranium, arsenic and other metals to the soil, water and air. We recently reported that hypertension is associated with mine waste exposures in this population. Inflammation is a major player in the development of numerous vascular ailments. Our previous work establishing that specific transcriptional responses of cultured endothelial cells treated with human serum can reveal relative circulating inflammatory potential in a manner responsive to pollutant exposures, providing a model to assess responses associated with exposure to these waste materials in this population. To investigate a potential link between exposures to AUM and serum inflammatory potential in affected communities, primary human coronary artery endothelial cells were treated for 4 h with serum provided by Navajo study participants (n=145). Endothelial transcriptional responses of intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1) and chemokine ligand 2 (CCL2) were measured. These transcriptional responses were then linked to AUM exposure metrics, including surface area-weighted AUM proximity and estimated oral intake of metals. AUM proximity strongly predicted endothelial transcriptional responses to serum including CCL2, VCAM-1 and ICAM-1 (Puranium did not, even after controlling for all major effect modifiers. Inflammatory potential associated with proximity to AUMs, but not oral intake of specific metals, additionally suggests a role for inhalation exposure as a contributor to cardiovascular disease.

  3. An expose of bioenergy and its potential and utilization in Turkey

    International Nuclear Information System (INIS)

    Erdogdu, Erkan

    2008-01-01

    Turkey is heavily dependent on expensive imported energy resources (oil, gas and coal) that place a big burden on the economy. Air pollution is also becoming a great environmental concern in the country. In this regard, renewable energy resources appear to be one of the most efficient and effective solutions for clean and sustainable energy development in Turkey. Turkey's renewable sources are the second largest source for energy production after coal. About two-thirds of the renewable energy produced is obtained from bioenergy, which is used to meet a variety of energy needs, including generating electricity, heating homes, fueling vehicles and providing process heat for industrial facilities. The amount of usable bioenergy potential of Turkey is approximately 17 Mtoe. This article not only presents a review of the potential and utilization of the bioenergy in Turkey but also provides some guidelines for policy makers

  4. Genotypic variation in phytoremediation potential of Indian mustard exposed to nickel stress: a hydroponic study.

    Science.gov (United States)

    Ansari, Mohd Kafeel Ahmad; Ahmad, Altaf; Umar, Shahid; Zia, Munir Hussain; Iqbal, Muhammad; Owens, Gary

    2015-01-01

    Ten Indian mustard (Brassica juncea L.) genotypes were screened for their nickel (Ni) phytoremediation potential under controlled environmental conditions. All ten genotypes were grown hydroponically in aqueous solution containing Ni concentrations (as nickel chloride) ranging from 0 to 50 μM and changes in plant growth, biomass and total Ni uptake were evaluated. Of the ten genotypes (viz. Agrini, BTO, Kranti, Pusa Basant, Pusa Jai Kisan, Pusa Bahar, Pusa Bold, Vardhan, Varuna, and Vaibhav), Pusa Jai Kisan was the most Ni tolerant genotype accumulating up to 1.7 μg Ni g(-1) dry weight (DW) in its aerial parts. Thus Pusa Jai Kisan had the greatest potential to become a viable candidate in the development of practical phytoremediation technologies for Ni contaminated sites.

  5. Bovine coronavirus in naturally andexperimentally exposed calves; viralshedding and the potential for transmission

    OpenAIRE

    Oma, Veslemøy Sunniva; Tråven, Madeleine; Alenius, S.; Myrmel, Mette; Stokstad, Maria

    2016-01-01

    Background Bovine coronavirus (BCoV) is a widely distributed pathogen, causing disease and economic losses in the cattle industry worldwide. Prevention of virus spread is impeded by a lack of basic knowledge concerning viral shedding and transmission potential in individual animals. The aims of the study were to investigate the duration and quantity of BCoV shedding in feces and nasal secretions related to clinical signs, the presence of virus in blood and tissues and to test the hypothesis t...

  6. Potential fields on the ventricular surface of the exposed dog heart during normal excitation.

    Science.gov (United States)

    Arisi, G; Macchi, E; Baruffi, S; Spaggiari, S; Taccardi, B

    1983-06-01

    We studied the normal spread of excitation on the anterior and posterior ventricular surface of open-chest dogs by recording unipolar electrograms from an array of 1124 electrodes spaced 2 mm apart. The array had the shape of the ventricular surface of the heart. The electrograms were processed by a computer and displayed as epicardial equipotential maps at 1-msec intervals. Isochrone maps also were drawn. Several new features of epicardial potential fields were identified: (1) a high number of breakthrough points; (2) the topography, apparent widths, velocities of the wavefronts and the related potential drop; (3) the topography of positive potential peaks in relation to the wavefronts. Fifteen to 24 breakthrough points were located on the anterior, and 10 to 13 on the posterior ventricular surface. Some were in previously described locations and many others in new locations. Specifically, 3 to 5 breakthrough points appeared close to the atrioventricular groove on the anterior right ventricle and 2 to 4 on the posterior heart aspect; these basal breakthrough points appeared when a large portion of ventricular surface was still unexcited. Due to the presence of numerous breakthrough points on the anterior and posterior aspect of the heart which had not previously been described, the spread of excitation on the ventricular surface was "mosaic-like," with activation wavefronts spreading in all directions, rather than radially from the two breakthrough points, as traditionally described. The positive potential peaks which lay ahead of the expanding wavefronts moved along preferential directions which were probably related to the myocardial fiber direction.

  7. Survey of public participation potential regarding the Muria NPP program

    International Nuclear Information System (INIS)

    Yarianto-SBS; Sri Hariani Syarif; Heni Susiati; Imam Hamzah; Fepriadi

    2003-01-01

    Socio-culture aspect is a part of site feasibility evaluation of Nuclear Power Plant (NPP)program. Indonesia is under going democratization, therefore the paradigm of development has also been changed where the people have freedom or liberty and they can express their opinion independently. The people are significant factor that involving in the decision making of regional development.Even the socio-culture, such as social riot can reject the site. Therefore socio-culture aspect should be considered in the NPP site evaluation. The first step of the study,mapping of public participation potential should be conducted by field survey. The method used in there search is quantitative approach with field survey guided by questioner without any treatment of object sampled. Qualitative approach was also conducted by in-depth interview technique to collect more detailed information. Information were collected from general public without any stratification in the 10 km radius from NPP site. Sampling method used was full random sampling technique. The results of survey show that the most of the people have significant potential for participating in the NPP Program. Conducive atmosphere should be maintained by social setting, therefore the present good momentum will not be lost. (author)

  8. RAGE-dependent potentiation of TRPV1 currents in sensory neurons exposed to high glucose.

    Science.gov (United States)

    Lam, Doris; Momeni, Zeinab; Theaker, Michael; Jagadeeshan, Santosh; Yamamoto, Yasuhiko; Ianowski, Juan P; Campanucci, Verónica A

    2018-01-01

    Diabetes mellitus is associated with sensory abnormalities, including exacerbated responses to painful (hyperalgesia) or non-painful (allodynia) stimuli. These abnormalities are symptoms of diabetic peripheral neuropathy (DPN), which is the most common complication that affects approximately 50% of diabetic patients. Yet, the underlying mechanisms linking hyperglycemia and symptoms of DPN remain poorly understood. The transient receptor potential vanilloid 1 (TRPV1) channel plays a central role in such sensory abnormalities and shows elevated expression levels in animal models of diabetes. Here, we investigated the function of TRPV1 channels in sensory neurons cultured from the dorsal root ganglion (DRG) of neonatal mice, under control (5mM) and high glucose (25mM) conditions. After maintaining DRG neurons in high glucose for 1 week, we observed a significant increase in capsaicin (CAP)-evoked currents and CAP-evoked depolarizations, independent of TRPV1 channel expression. These functional changes were largely dependent on the expression of the receptor for Advanced Glycation End-products (RAGE), calcium influx, cytoplasmic ROS accumulation, PKC, and Src kinase activity. Like cultured neurons from neonates, mature neurons from adult mice also displayed a similar potentiation of CAP-evoked currents in the high glucose condition. Taken together, our data demonstrate that under the diabetic condition, DRG neurons are directly affected by elevated levels of glucose, independent of vascular or glial signals, and dependent on RAGE expression. These early cellular and molecular changes to sensory neurons in vitro are potential mechanisms that might contribute to sensory abnormalities that can occur in the very early stages of diabetes.

  9. Posttraumatic stress among young urban children exposed to family violence and other potentially traumatic events.

    Science.gov (United States)

    Crusto, Cindy A; Whitson, Melissa L; Walling, Sherry M; Feinn, Richard; Friedman, Stacey R; Reynolds, Jesse; Amer, Mona; Kaufman, Joy S

    2010-12-01

    This study examines the relationship between the number of types of traumatic events experienced by children 3 to 6 years old, parenting stress, and children's posttraumatic stress (PTS). Parents and caregivers provided data for 154 urban children admitted into community-based mental health or developmental services. By parent and caregiver report, children experienced an average of 4.9 different types of potentially traumatic events. Nearly one quarter of the children evidenced clinically significant PTS. Posttraumatic stress was positively and significantly related to family violence and other family-related trauma exposure, nonfamily violence and trauma exposure, and parenting stress. Additionally, parenting stress partially mediated the relationship between family violence and trauma exposure and PTS. This study highlights the need for early violence and trauma exposure screening in help-seeking populations so that appropriate interventions are initiated. Copyright © 2010 International Society for Traumatic Stress Studies.

  10. Posttraumatic Stress among Young Urban Children Exposed to Family Violence and Other Potentially Traumatic Events

    Science.gov (United States)

    Crusto, Cindy A.; Whitson, Melissa L.; Walling, Sherry N.; Feinn, Richard; Friedman, Stacey R.; Reynolds, Jesse; Amer, Mona; Kaufman, Joy S.

    2014-01-01

    This study examines the relationship between the number of types of traumatic events experienced by children 3 to 6 years old, parenting stress, and children’s posttraumatic stress (PTS). Parents/caregivers provided data for 154 urban children admitted into community-based mental health and/or developmental services. By parent/caregiver report, children experienced an average of 4.9 different types of potentially traumatic events. Nearly one-quarter of the children evidenced clinically significant PTS. PTS was positively and significantly related to family violence and other family-related trauma exposure, nonfamily violence/trauma exposure, and parenting stress. Additionally, parenting stress partially mediated the relationship between family violence/trauma exposure and PTS. This study highlights the need for early violence/trauma exposure screening in help-seeking populations so that appropriate interventions are initiated. PMID:21171132

  11. Adaptogenic potential of royal jelly in liver of rats exposed to chronic stress.

    Directory of Open Access Journals (Sweden)

    Douglas Carvalho Caixeta

    Full Text Available Restraint and cold stress increase both corticosterone and glycemia, which lead to oxidative damages in hepatic tissue. This study assessed the effect of royal jelly (RJ supplementation on the corticosterone level, glycemia, plasma enzymes and hepatic antioxidant system in restraint and cold stressed rats. Wistar rats were allocated into no-stress, stress, no-stress supplemented with RJ and stress supplemented with RJ groups. Initially, RJ (200mg/Kg was administered for fourteen days and stressed groups were submitted to chronic stress from the seventh day. The results showed that RJ supplementation decreases corticosterone levels and improves glycemia control after stress induction. RJ supplementation also decreased the body weight, AST, ALP and GGT. Moreover, RJ improved total antioxidant capacity, SOD activity and reduced GSH, GR and lipoperoxidation in the liver. Thus, RJ supplementation reestablished the corticosterone levels and the hepatic antioxidant system in stressed rats, indicating an adaptogenic and hepatoprotective potential of RJ.

  12. Mandating nutrient menu labeling in restaurants: potential public health benefits.

    Science.gov (United States)

    Stran, Kimberly A; Turner, Lori W; Knol, Linda

    2013-03-01

    Many Americans have replaced home-cooked meals with fast food and restaurants meals. This contributes to increased incidences of overweight and obesity. Implementing policies that require restaurants to disclose nutrition information has the potential to improve nutrition knowledge and food behaviors. The purpose of this paper was to examine the potential health benefits of nutrient menu labeling in restaurants, the progress of this legislation and to provide results regarding the implementation of these policies. Data sources were obtained from a search of multiple databases including PubMed, Science Direct, Academic Search Premier, and Google Scholar. Study inclusion criteria were publication in the past ten years, obesity prevention, and utilization of nutrition labeling on menus in restaurants. The initial policies to provide consumers with nutrition information in restaurant settings began at the state levels in 2006. These laws demonstrated success, other states followed, and a national law was passed and is being implemented. Mandating nutrient menu disclosure has the potential to influence a large number of people; this legislation has the opportunity to impact Americans who dine at a fast food or chain restaurant. Given the growing obesity epidemic, continued research is necessary to gauge the effectiveness of this new law and its effects on the health status of the American people.

  13. Public services between the citizen need and administration potential

    OpenAIRE

    Grigorescu, Adriana

    2010-01-01

    This paper aims at the balance between the citizen and the public authorities with public services as an interface. Public services place themselves at the crossroads of many elements such as: needs of the citizen, social need, public will, public resources, private availability, and civic sense. Without claiming to have identified all factors that converge to defining / structuring the SP / GIS, the paper tried to highlight some of the most important. The social need is covered at the macro ...

  14. Active and retired public employees' health insurance: potential data sources.

    Science.gov (United States)

    Morrill, Melinda Sandler

    2014-12-01

    Employer-provided health insurance for public sector workers is a significant public policy issue. Underfunding and the growing costs of benefits may hinder the fiscal solvency of state and local governments. Findings from the private sector may not be applicable because many public sector workers are covered by union contracts or salary schedules and often benefit modifications require changes in legislation. Research has been limited by the difficulty in obtaining sufficiently large and representative data on public sector employees. This article highlights data sources researchers might utilize to investigate topics concerning health insurance for active and retired public sector employees. Copyright © 2014 Elsevier B.V. All rights reserved.

  15. Tetanus: A Potential Public Health Threat in Times of Disaster.

    Science.gov (United States)

    Finkelstein, Paige; Teisch, Laura; Allen, Casey J; Ruiz, Gabriel

    2017-06-01

    for trauma and critical patients to become familiar with the protocols for treatment and immunization of patients that have tetanus-prone wounds, as well as recognize the potential for outbreaks in the settings of major natural disasters. Finkelstein P , Teisch L , Allen CJ , Ruiz G . Tetanus: a potential public health threat in times of disaster. Prehosp Disaster Med. 2017;32(3):339-342.

  16. Abnormal sympathetic nerve activity in women exposed to cigarette smoke: a potential mechanism to explain increased cardiac risk.

    Science.gov (United States)

    Middlekauff, Holly R; Park, Jeanie; Agrawal, Harsh; Gornbein, Jeffrey A

    2013-11-15

    In women, cardiac deaths attributable to tobacco exposure have reached the same high levels as men. Normally, sympathetic nerve activity (SNA) fluctuates according to the menstrual phase, but in habitual smokers, SNA levels remain constant. Our purpose is to extend these observations to other groups of women exposed to tobacco smoke and to explore potential mechanisms. We hypothesize that women exposed to secondhand smoke, but not former smokers, have nonfluctuating SNA compared with never smokers, and that impaired baroreflex suppression of SNA, and/or heightened central SNA responses, underlie this nonfluctuating SNA. We also hypothesize that female smokers have impaired nocturnal blood pressure dipping, normally mediated by modulation of SNA. In 49 females (19 never, 12 current, 9 former, 9 passive smokers), SNA was recorded (microneurography) during high- and low-hormone ovarian phases at rest, during pharmacological baroreflex testing, and during the cold pressor test (CPT). Twenty-four hour blood pressure (BP) monitoring was performed. Current and passive smokers, but not former smokers, had a nonfluctuating pattern of SNA, unlike never smokers in whom SNA varied with the menstrual phase. Baroreflex control of SNA was significantly blunted in current smokers, independent of menstrual phase. In passive smokers, SNA response to CPT was markedly increased. Nondipping was unexpectedly high in all groups. SNA does not vary during the menstrual cycle in active and passive smokers, unlike never and former smokers. Baroreflex control of SNA is blunted in current smokers, whereas SNA response to CPT is heightened in passive smokers. Smoking cessation is associated with return of the altered SNA pattern to normal.

  17. Dispersal and survival rates of adult and juvenile Red-tailed tropicbirds (Phaethon rubricauda exposed to potential contaminants

    Directory of Open Access Journals (Sweden)

    Schreiber, E. A.

    2004-06-01

    Full Text Available Annual survival and dispersal rates of adult and juvenile red-tailed tropicbirds were examined in connection with exposure to heavy metals. From 1990-2000 the incineration of a U.S. stockpile of chemical weapons stored at Johnston Atoll exposed nesting tropicbirds to increased levels of human disturbance, smoke stack emissions and potential leaks. Using a multi-state mark-recapture modeling approach, birds nesting in this site (downwind of the plant were compared to those nesting in a reference site (upwind of the plant with less human disturbance, no exposure to smoke stack emissions or other potential incineration emissions. We did not find any difference in survival of adults or juveniles when comparing the two sites. Adult breeding dispersal rates did not differ between the sites but we did find differences in the age-specific natal dispersal rates. Birds fledged from downwind areas were less likely to return to their natal area to nest and more likely to immigrate to the upwind area than vice-versa. This asymmetry in emigration rates is believed to be due to differing vegetation densities and has implications for vegetation management in relation to tropicbird nest success and population size.

  18. Assessment of potential biomarkers, metallothionein and vitellogenin mRNA expressions in various chemically exposed benthic Chironomus riparius larvae

    Science.gov (United States)

    Park, Kiyun; Kwak, Inn-Sil

    2012-12-01

    The objective of this study was conducted to identify the possibility of using Chironomus metallothionein (MT) and vitellogenin (VTG) as biomarkers of stress caused by endocrinedisrupting chemicals (EDCs), heavy metals, herbicides and veterinary antibiotics. We characterized the MT and VTG cDNA in Chironomus riparius and evaluated their mRNA expression profiles following exposure to different environmental pollutants. The gene expression analysis showed that the MT mRNA levels increased significantly after long-term exposure to cadmium (Cd), copper (Cu), Lead (Pb), di(2-ethylhexyl) phthalate (DEHP), and 2,4-dichlorophenoxyacetic acid (2,4-D). Moreover, the VTG mRNA expression increased significantly in C. riparius larvae exposed to BPA, NP, DEHP, Cd, 2,4-D and fenbendazole. Evaluation of the long-term effects of environmental pollutants revealed up regulation of Chironomus MT mRNA in response to DEHP exposure among EDCs, and the level of the VTG mRNA was increased significantly following treatment with Cd and herbicide 2,4-D at all concentrations in a dose-dependent manner. These results indicate that VTG could be used as a potential biomarker of herbicide and Cd as well as EDCs, while MT was a potential biomarker of heavy metals such as Cd, Cu, and Pb in aquatic environments.

  19. Waste dumpsites and public health: a case for lead exposure in Zimbabwe and potential global implications.

    Science.gov (United States)

    Tongesayi, Tsanangurayi; Kugara, Jameson; Tongesayi, Sunungurai

    2018-02-01

    Most waste sites in Zimbabwe are not sanitary landfills but open dumps that indiscriminately receive waste from municipalities, industries, commercial establishments, and social services establishments. People, including children, who eke out a living through scavenging the dumps expose themselves to environmental pollutants at the dumps via inadvertent ingestion and inhalation of contaminated dust, and dermal absorption. The public is potentially being exposed to a slew of the pollutants via air, water, and food, all contaminated by uncontrolled leachates and aerially deposited dust and particulates from the sites. One of the unfortunate consequences of globalization is the sharing of contaminated food and the associated disease burdens; hence, regional contamination can have global impacts. We analyzed the levels of lead at two waste sites in Zimbabwe to assess the daily exposure levels of Pb to children and adults who scavenge the sites as well as determine levels of the heavy metal that are potentially contaminating air, water, soils, and food in the country. Levels of Pb ranged from 23,000 to 14,600,000 µg/kg at one of the sites and from 30,000 to 1,800,000 µg/kg at the other. Inadvertent daily exposure amounts that were calculated by assuming an inadvertent daily ingestion of 20-500 mg of soil/dust were mostly higher than the provisional tolerable daily intake established by the World Health Organization for infants, children, and adults. The XRF measurements were validated using certified reference samples, 2710a (Montana soil) and 2781 (domestic sludge), from the National Institute of Standards and Technology.

  20. In-Situ Strain Analysis of Potential Habitat Composites Exposed to a Simulated Long-Term Lunar Radiation Exposure

    Science.gov (United States)

    Rojdev, Kristina; O'Rourke, Mary Jane; Hill, Charles; Nutt, Steven; Atwell, William

    2010-01-01

    NASA is studying the effects of long-term space radiation on potential multifunctional composite materials for habitats to better determine their characteristics in the harsh space environment. Two composite materials were selected for the study and were placed in a test stand that simulated the stresses of a pressure vessel wall on the material. The samples in the test stand were exposed to radiation at either a fast dose rate or a slow dose rate, and their strain and temperature was recorded during the exposure. It was found that during a fast dose rate exposure the materials saw a decreased strain with time, or a shrinking of the materials. Given previous radiation studies of polymers, this is believed to be a result of crosslinking occurring in the matrix material. However, with a slow dose rate, the materials saw an increase in strain with time, or a stretching of the materials. This result is consistent with scission or degradation of the matrix occurring, possibly due to oxidative degradation.

  1. Examining the Potential Travellers in Catchment Areas for Public Transport

    DEFF Research Database (Denmark)

    Landex, Alex; Hansen, Stephen

    2006-01-01

    The paper presents a method to examine the catchment areas for stops in high quality public transport systems based on the actual street network in the examined area. This is achieved by implementing the service area functions from the ArcGIS extension Network Analyst. The method is compared...

  2. WEpods project : Finding the potential for automated road public transport

    NARCIS (Netherlands)

    Homem De Almeida Rodriguez Correia, G.

    2016-01-01

    Vehicle automation is developing rapidly, nevertheless a lot of wor k is still lacking, as we are not yet at a point where vehicles are able to drive themselves on a road without a human behind the wheel. One of the possibilities of automation is its use as public transport. In theWEpods project,

  3. Educational potential of public music lectures at Kazan Federal ...

    African Journals Online (AJOL)

    Journal of Fundamental and Applied Sciences ... The conducted research allowed determining the conditions (continuous self-education, updating and integration ... expansion of research and execution potential on the basis of scientific and ... and actualization of the motivational potential of the educational environment on ...

  4. Environmentally induced epigenetic toxicity: potential public health concerns.

    Science.gov (United States)

    Marczylo, Emma L; Jacobs, Miriam N; Gant, Timothy W

    2016-09-01

    Throughout our lives, epigenetic processes shape our development and enable us to adapt to a constantly changing environment. Identifying and understanding environmentally induced epigenetic change(s) that may lead to adverse outcomes is vital for protecting public health. This review, therefore, examines the present understanding of epigenetic mechanisms involved in the mammalian life cycle, evaluates the current evidence for environmentally induced epigenetic toxicity in human cohorts and rodent models and highlights the research considerations and implications of this emerging knowledge for public health and regulatory toxicology. Many hundreds of studies have investigated such toxicity, yet relatively few have demonstrated a mechanistic association among specific environmental exposures, epigenetic changes and adverse health outcomes in human epidemiological cohorts and/or rodent models. While this small body of evidence is largely composed of exploratory in vivo high-dose range studies, it does set a precedent for the existence of environmentally induced epigenetic toxicity. Consequently, there is worldwide recognition of this phenomenon, and discussion on how to both guide further scientific research towards a greater mechanistic understanding of environmentally induced epigenetic toxicity in humans, and translate relevant research outcomes into appropriate regulatory policies for effective public health protection.

  5. Potential impacts of nuclear power plant operation on the public

    International Nuclear Information System (INIS)

    Kotulan, J.

    1999-01-01

    Findings from the examination of the health status of population living in the vicinity of nuclear facilities abroad (England, France, Germany ...) are summarized. Where a significant increase in the incidence of leukemia in children and non-Hodgkin's lymphomas were observed, these are not attributed to radioactivity; rather, the virus theory seems to account best for this phenomenon. Author's findings in the area of the Dukovany NPP in the Czech Republic (which have been published) are summarized as follows: (i) Total mortality 1986-1994 in the vicinity of the plant is the same as or lower than in reference regions; (ii) This also applies to premature deaths and to the 'lost years' indicator; (iii) Death rate due to tumors is significantly lower than in reference regions; (iv) This also applies to the majority of the individual types of tumors; (v) Leukemia seems to be an exception, its incidence being higher than in reference regions. The absolute figures, however, are low (11 + 17 in the exposed region) and the differences are not statistically significant. This also applies to lymphatic tissue tumors. (7) Mental well-being was no different from the reference region; in some respects, surprisingly enough, it even appeared to be more favourable. (P.A.)

  6. Yellow Fever Remains a Potential Threat to Public Health.

    Science.gov (United States)

    Vasconcelos, Pedro F C; Monath, Thomas P

    2016-08-01

    Yellow fever (YF) remains a serious public health threat in endemic countries. The recent re-emergence in Africa, initiating in Angola and spreading to Democratic Republic of Congo and Uganda, with imported cases in China and Kenya is of concern. There is such a shortage of YF vaccine in the world that the World Health Organization has proposed the use of reduced doses (1/5) during emergencies. In this short communication, we discuss these and other problems including the risk of spread of YF to areas free of YF for decades or never before affected by this arbovirus disease.

  7. Assessing the Potential for Renewable Energy on Public Lands

    Energy Technology Data Exchange (ETDEWEB)

    2003-02-01

    This report represents an initial activity of the Bureau of Land Managements (BLM) proposed National Energy Policy Implementation Plan: identify and evaluate renewable energy resources on federal lands and any limitations on accessing them. Ultimately, BLM will prioritize land-use planning activities to increase industrys development of renewable energy resources. These resources include solar, biomass, geothermal, water, and wind energy. To accomplish this, BLM and the Department of Energys National Renewable Energy Laboratory (NREL) established a partnership to conduct an assessment of renewable energy resources on BLM lands in the western United States. The objective of this collaboration was to identify BLM planning units in the western states with the highest potential for private-sector development of renewable resources. The assessment resulted in the following findings: (1) 63 BLM planning units in nine western states have high potential for one or more renewable energy technologies; and (2) 20 BLM planning units in seven western states have high potential for power production from three or more renewable energy sources. This assessment report provides BLM with information needed to prioritize land-use planning activities on the basis of potential for the development of energy from renewable resources.

  8. Decreased in vitro fertility in male rats exposed to fluoride-induced oxidative stress damage and mitochondrial transmembrane potential loss

    International Nuclear Information System (INIS)

    Izquierdo-Vega, Jeannett A.; Sanchez-Gutierrez, Manuel; Razo, Luz Maria del

    2008-01-01

    Fluorosis, caused by drinking water contamination with inorganic fluoride, is a public health problem in many areas around the world. The aim of the study was to evaluate the effect of environmentally relevant doses of fluoride on in vitro fertilization (IVF) capacity of spermatozoa, and its relationship to spermatozoa mitochondrial transmembrane potential (ΔΨ m ). Male Wistar rats were administered at 5 mg fluoride/kg body mass/24 h, or deionized water orally for 8 weeks. We evaluated several spermatozoa parameters in treated and untreated rats: i) standard quality analysis, ii) superoxide dismutase (SOD) activity, iii) the generation of superoxide anion (O 2 ·- ), iv) lipid peroxidation concentration, v) ultrastructural analyses of spermatozoa using transmission electron microscopy, vi) ΔΨ m , vii) acrosome reaction, and viii) IVF capability. Spermatozoa from fluoride-treated rats exhibited a significant decrease in SOD activity (∼ 33%), accompanied with a significant increase in the generation of O 2 · (∼ 40%), a significant decrease in ΔΨ m (∼ 33%), and a significant increase in lipid peroxidation concentration (∼ 50%), relative to spermatozoa from the control group. Consistent with this finding, spermatozoa from fluoride-treated rats exhibited altered plasmatic membrane. In addition, the percentage of fluoride-treated spermatozoa capable of undergoing the acrosome reaction was decreased relative to control spermatozoa (34 vs. 55%), while the percentage fluoride-treated spermatozoa capable of oocyte fertilization was also significantly lower than the control group (13 vs. 71%). These observations suggest that subchronic exposure to fluoride causes oxidative stress damage and loss of mitochondrial transmembrane potential, resulting in reduced fertility

  9. 77 FR 16205 - National Defense Stockpile Market Impact Committee Request for Public Comments on the Potential...

    Science.gov (United States)

    2012-03-20

    .... The Committee is seeking public comments on the potential market impact of the material research and... Defense Stockpile Market Impact Committee Request for Public Comments on the Potential Market Impact of... National Defense Stockpile Market Impact Committee, co-chaired by the Departments of Commerce and State, is...

  10. Substandard drugs: a potential crisis for public health

    Science.gov (United States)

    Johnston, Atholl; Holt, David W

    2014-01-01

    Poor-quality medicines present a serious public health problem, particularly in emerging economies and developing countries, and may have a significant impact on the national clinical and economic burden. Attention has largely focused on the increasing availability of deliberately falsified drugs, but substandard medicines are also reaching patients because of poor manufacturing and quality-control practices in the production of genuine drugs (either branded or generic). Substandard medicines are widespread and represent a threat to health because they can inadvertently lead to healthcare failures, such as antibiotic resistance and the spread of disease within a community, as well as death or additional illness in individuals. This article reviews the different aspects of substandard drug formulation that can occur (for example, pharmacological variability between drug batches or between generic and originator drugs, incorrect drug quantity and presence of impurities). The possible means of addressing substandard manufacturing practices are also discussed. A concerted effort is required on the part of governments, drug manufacturers, charities and healthcare providers to ensure that only drugs of acceptable quality reach the patient. PMID:24286459

  11. Exposing diversity

    DEFF Research Database (Denmark)

    Nørtoft, Kamilla; Nordentoft, Helle Merete

    professionals´ meetings with patients and relatives. In the paper we draw data from focus group discussions with interdisciplinary groups of health care professionals working in the area of care for older people. The video narratives used to initiate discussions are developed through ethnographic fieldwork...... in the homes of older people and in pedagogical institutions targeting older people. In the paper we look at the potentials and challenges in working with ethnographic video narratives as a pedagogical tool. Our findings indicate that the use of video narratives has the potential to expose the diversity...... focus on their own professional discipline and its tasks 2) stimulates collaborative learning when they discuss their different interpretations of the ethnographic video narratives and achieve a deeper understanding of each other’s work and their clients’ lifeworlds, which might lead to a better...

  12. Public protection strategies for potential nuclear reactor accidents: sheltering concepts with existing public and private structures

    International Nuclear Information System (INIS)

    Aldrich, D.C.; Ericson, D.M. Jr.; Johnson, J.D.

    1978-02-01

    Three generic sheltering/relocation strategies are identified and discussed. They are: population relocation only (no specific sheltering response initiated); sheltering at location following by relocation; and preferential sheltering followed by relocation. Shielding factors representative of these strategies are calculated, and the adequacy of using average shielding factors for the calculation of public health effects is discussed

  13. Potential reduction of energy consumption in public university library

    Science.gov (United States)

    Noranai, Z.; Azman, ADF

    2017-09-01

    Efficient electrical energy usage has been recognized as one of the important factor to reduce cost of electrical energy consumption. Various parties have been emphasized about the importance of using electrical energy efficiently. Inefficient usage of electrical energy usage lead to biggest factor increasing of administration cost in Universiti Tun Hussein Onn Malaysia. With this in view, a project the investigate potential reduction electrical energy consumption in Universiti Tun Hussein Onn Malaysia was carried out. In this project, a case study involving electrical energy consumption of Perpustakaan Tunku Tun Aminah was conducted. The scopes of this project are to identify energy consumption in selected building and to find the factors that contributing to wastage of electrical energy. The MS1525:2001, Malaysian Standard - Code of practice on energy efficiency and use of renewable energy for non-residential buildings was used as reference. From the result, 4 saving measure had been proposed which is change type of the lamp, install sensor, decrease the number of lamp and improve shading coefficient on glass. This saving measure is suggested to improve the efficiency of electrical energy consumption. Improve of human behaviour toward saving energy measure can reduce 10% from the total of saving cost while on building technical measure can reduce 90% from total saving cost.

  14. Carbon offset potentials and design: Anticipating future public policy

    International Nuclear Information System (INIS)

    Trexler, M.C.; Kosloff, L.H.; Gowen, M.

    1994-01-01

    Carbon offsets offer CO 2 emitters the opportunity to compensate for some proportion of their CO 2 emissions through the pursuit of emissions reduction or carbon sequestration projects beyond their own operational boundaries. The flexibility to pursue carbon offsets ''off-site'' can dramatically reduce the costs of achieving a given net emissions reduction. The future role of carbon offsets, however, continues to be a topic of considerable debate. Several processes are currently under way nationally and internationally that will help shape this role. This paper discusses how alternative policy outcomes could encourage or restrict the viability of carbon offsets as a component of corporate climate change mitigation portfolios and proposes criteria by which projects should be evaluated prior to the finalization of national or international policy frameworks. Based on these outcomes, the potential for offsets could be very large or very modest. It is vital that policy development in the offset arena account for the still voluntary nature of mitigation efforts and that the objective of climate change mitigation not be forgotten in the push for offset rules and regulations. At the same time, carbon offsets are far from a panacea for climate change mitigation and should be evaluated in the context of a larger global mitigation portfolio

  15. Ocean acidification effects on calcification in Caribbean scleractinian coral exposed to elevated pCO2: a potential for acclimation

    Science.gov (United States)

    Hankins, C.

    2016-02-01

    Ocean acidification (OA) is projected to increase the acidity of coral reef habitats 2-3 times that of present day pCO2 levels. Many studies have shown the adverse effects on scleractinian calcification when exposed to elevated pCO2 levels, however, no such effects were seen in this study whereby corals were exposed for three months to elevated pCO2 levels. In this study, all corals were kept in culture for one year prior to being used in experimental trials. Data from culture systems shows coral experience a range of pCO2 from 300-600 µatm over the course of a day. This range is attributed to respiration and photosynthesis which also naturally occurs in a reef habitat. Montastrea cavernosa, Orbicella faveolata, and Pseudodiploria clivosa were exposed to their ambient culture conditions (control) or to elevated pCO2 levels of 1000 µatm (IPCC A1F1 scenario). By combining photographic analysis of live tissue area or exposed skeleton with the buoyant weight technique, an area density of each coral fragment was obtained to infer rates of calcification or erosion of skeleton. After three months of experimental exposure, preliminary results suggest that there is no significant difference in calcification or erosion in any of the species tested. Acclimation in the elevated pCO2 culture environment may have conditioned the coral to better withstand high pCO2 levels. Long acclimation periods of coral to near term future pCO2 levels may more accurately predict calcification responses in corals of the future.

  16. Paleomagnetism of the Grande Ronde (lower Yakima) basalt exposed at Sentinel Gap: potential use for stratigraphic correlation

    International Nuclear Information System (INIS)

    Coe, R.S.; Bogue, S.; Myers, C.W.

    1978-01-01

    Directions of natural remanent magnetization were measured in each of the twelve superposed Grande Ronde (lower Yakima) Basalt flows exposed at Sentinel Gap, Washington. The sequence of changes in the natural remanent magnetism direction in these flows is sufficiently distinct that identification and correlation at other surface- and subsurface-sampling sites should be possible. Preliminary tests made on the feasibility of measuring variations in the ancient field intensity in these flows indicate they are not suitable for intensity measurements

  17. Immunizing potential of sporulated oocysts of Eimeria nieschulzi exposed to heat and 60Co gamma-radiation

    International Nuclear Information System (INIS)

    Conder, G.A.; Duszynski, D.W.

    1977-01-01

    Sporulated oocysts of Eimeria nieschulzi Dieben 1924, a rat coccidium, were exposed to radiation, heat, or both in an effort to attenuate the parasite. Moderate levels of each treatment or combination thereof attenuated the parasite, reduced pathogenesis (as judged by oocyst discharge during primary infection), and produced immunity to challenge when the oocysts were subsequently inoculated into rats. Thus, heat- and/or radiation-treated E. nieschulzi oocysts fed to rats could reduce pathogenesis during a primary infection and yet give good homologous protection

  18. Liver proteome response of largemouth bass (Micropterus salmoides) exposed to several environmental contaminants: Potential insights into biomarker development

    International Nuclear Information System (INIS)

    Sanchez, Brian C.; Ralston-Hooper, Kimberly J.; Kowalski, Kevin A.; Dorota Inerowicz, H.; Adamec, Jiri; Sepulveda, Maria S.

    2009-01-01

    Liver proteome response of largemouth bass (Micropterus salmoides) exposed to environmental contaminants was analyzed to identify novel biomarkers of exposure. Adult male bass were exposed to cadmium chloride (CdCl 2 ), atrazine, PCB 126, phenanthrene, or toxaphene via intraperitoneal injection with target body burdens of 0.00067, 3.0, 2.5, 50, and 100 μg/g, respectively. After a 96 h exposure, hepatic proteins were separated with two-dimensional gel electrophoresis and differentially expressed proteins (vs. controls) recognized and identified with MALDI-TOF/TOF mass spectrometry. We identified, 30, 18, eight, 19, and five proteins as differentially expressed within the CdCl 2 , atrazine, PCB 126, phenanthrene, and toxaphene treatments, respectively. Alterations were observed in the expression of proteins associated with cellular ion homeostasis (toxaphene), oxidative stress (phenanthrene, PCB 126), and energy production including glycolysis (CdCl 2 , atrazine) and ATP synthesis (atrazine). This work supports the further evaluation of several of these proteins as biomarkers of contaminant exposure in fish.

  19. Public Diplomacy in Prime Time: Exploring the Potential of Entertainment Education in International Public Diplomacy

    Science.gov (United States)

    Murphy, Sheila T.; Hether, Heather J.; Felt, Laurel J.; de Castro Buffington, Sandra

    2014-01-01

    Can stories succeed where traditional forms of diplomacy have faltered? This study examined whether a primetime drama could impact American viewers’ knowledge, attitudes, and behavior with respect to U.S. foreign policy and funding by surveying 173 viewers of an episode of Law & Order: SVU (“Witness”). Additionally, this study sought to uncover which theoretical construct — involvement with a specific character or involvement with the narrative more generally (transportation) — best predicted impact. The fictional character in question was Nardelie, a woman forced to flee the Democratic Republic of the Congo after repeated rape by militias vying for “conflict minerals,” so named because control of these valuable minerals has triggered numerous conflicts. Separate regression analyses suggested a positive relationship between impact of the storyline and both theoretical constructs. However, when both constructs were entered into a single regression, involvement with Nardelie was the stronger predictor of knowledge (e.g., conflict minerals, sexual violence, and asylum issues) and current or future behavior (i.e., discussing global health) while transportation was the stronger predictor of attitudes (i.e., support for aid). This suggests that, while correlated, these constructs do not completely overlap. Implications of these results and the use of entertainment education in public diplomacy are discussed. PMID:24489980

  20. Public Diplomacy in Prime Time: Exploring the Potential of Entertainment Education in International Public Diplomacy.

    Science.gov (United States)

    Murphy, Sheila T; Hether, Heather J; Felt, Laurel J; de Castro Buffington, Sandra

    2012-01-01

    Can stories succeed where traditional forms of diplomacy have faltered? This study examined whether a primetime drama could impact American viewers' knowledge, attitudes, and behavior with respect to U.S. foreign policy and funding by surveying 173 viewers of an episode of Law & Order: SVU ("Witness"). Additionally, this study sought to uncover which theoretical construct - involvement with a specific character or involvement with the narrative more generally (transportation) - best predicted impact. The fictional character in question was Nardelie, a woman forced to flee the Democratic Republic of the Congo after repeated rape by militias vying for "conflict minerals," so named because control of these valuable minerals has triggered numerous conflicts. Separate regression analyses suggested a positive relationship between impact of the storyline and both theoretical constructs. However, when both constructs were entered into a single regression, involvement with Nardelie was the stronger predictor of knowledge (e.g., conflict minerals, sexual violence, and asylum issues) and current or future behavior (i.e., discussing global health) while transportation was the stronger predictor of attitudes (i.e., support for aid). This suggests that, while correlated, these constructs do not completely overlap. Implications of these results and the use of entertainment education in public diplomacy are discussed.

  1. Surface potential distribution and airflow performance of different air-exposed electrode plasma actuators at different alternating current/direct current voltages

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Liang; Yan, Hui-Jie; Qi, Xiao-Hua; Hua, Yue; Ren, Chun-Sheng, E-mail: rchsh@dlut.edu.cn [School of Physics and Optoelectronic Technology, Key laboratory of Materials Modification by Laser, Ion and Electron Beams, Ministry of Education, Dalian University of Technology, Dalian 116023 (China)

    2015-04-15

    Asymmetric surface dielectric barrier discharge (SDBD) plasma actuators have been intensely studied for a number of years due to their potential applications for aerodynamic control. In this paper, four types of actuators with different configurations of exposed electrode are proposed. The SDBD actuators investigated are driven by dual-power supply, referred to as a fixed AC high voltage and an adjustable DC bias. The effects of the electrode structures on the dielectric surface potential distribution, the electric wind velocity, and the mean thrust production are studied, and the dominative factors of airflow acceleration behavior are revealed. The results have shown that the actions of the SDBD actuator are mainly dependent on the geometry of the exposed electrode. Besides, the surface potential distribution can effectively affect the airflow acceleration behavior. With the application of an appropriate additional DC bias, the surface potential will be modified. As a result, the performance of the electric wind produced by a single SDBD can be significantly improved. In addition, the work also illustrates that the actuators with more negative surface potential present better mechanical performance.

  2. Surface potential distribution and airflow performance of different air-exposed electrode plasma actuators at different alternating current/direct current voltages

    International Nuclear Information System (INIS)

    Yang, Liang; Yan, Hui-Jie; Qi, Xiao-Hua; Hua, Yue; Ren, Chun-Sheng

    2015-01-01

    Asymmetric surface dielectric barrier discharge (SDBD) plasma actuators have been intensely studied for a number of years due to their potential applications for aerodynamic control. In this paper, four types of actuators with different configurations of exposed electrode are proposed. The SDBD actuators investigated are driven by dual-power supply, referred to as a fixed AC high voltage and an adjustable DC bias. The effects of the electrode structures on the dielectric surface potential distribution, the electric wind velocity, and the mean thrust production are studied, and the dominative factors of airflow acceleration behavior are revealed. The results have shown that the actions of the SDBD actuator are mainly dependent on the geometry of the exposed electrode. Besides, the surface potential distribution can effectively affect the airflow acceleration behavior. With the application of an appropriate additional DC bias, the surface potential will be modified. As a result, the performance of the electric wind produced by a single SDBD can be significantly improved. In addition, the work also illustrates that the actuators with more negative surface potential present better mechanical performance

  3. Claudin-3 expression in radiation-exposed rat models: A potential marker for radiation-induced intestinal barrier failure

    Energy Technology Data Exchange (ETDEWEB)

    Shim, Sehwan; Lee, Jong-geol; Bae, Chang-hwan; Lee, Seung Bum [National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences, Seoul (Korea, Republic of); Jang, Won-Suk; Lee, Sun-Joo [Laboratory of Experimental Pathology, Korea Cancer Center Hospital, Seoul (Korea, Republic of); Lee, Seung-Sook [National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences, Seoul (Korea, Republic of); Department of Pathology, Korea Cancer Center Hospital, Seoul (Korea, Republic of); Park, Sunhoo, E-mail: sunhoo@kcch.re.kr [National Radiation Emergency Medical Center, Korea Institute of Radiological and Medical Sciences, Seoul (Korea, Republic of); Department of Pathology, Korea Cancer Center Hospital, Seoul (Korea, Republic of)

    2015-01-02

    Highlights: • Irradiation increased intestinal bacterial translocation, accompanied by claudin protein expression in rats. • Neurotensin decreased the bacterial translocation and restored claudin-3 expression. • Claudin-3 can be used as a marker in evaluating radiation induced intestinal injury. - Abstract: The molecular events leading to radiation-induced intestinal barrier failure are not well known. The influence of the expression of claudin proteins in the presence and absence of neurotensin was investigated in radiation-exposed rat intestinal epithelium. Wistar rats were randomly divided into control, irradiation, and irradiation + neurotensin groups, and bacterial translocation to the mesenteric lymph node and expression of claudins were determined. Irradiation led to intestinal barrier failure as demonstrated by significant bacterial translocation. In irradiated terminal ilea, expression of claudin-3 and claudin-4 was significantly decreased, and claudin-2 expression was increased. Administration of neurotensin significantly reduced bacterial translocation and restored the structure of the villi as seen by histologic examination. Among the three subtype of claudins, only claudin-3 expression was restored. These results suggest that the therapeutic effect of neurotensin on the disruption of the intestinal barrier is associated with claudin-3 alteration and that claudin-3 could be used as a marker in evaluating radiation-induced intestinal injury.

  4. 77 FR 42271 - National Defense Stockpile Market Impact Committee Request for Public Comments on the Potential...

    Science.gov (United States)

    2012-07-18

    ... comments on the potential market impact associated with the two material research and development projects... Defense Stockpile Market Impact Committee Request for Public Comments on the Potential Market Impact of... National Defense Stockpile Market Impact Committee, co-chaired by the Departments of Commerce and State, is...

  5. A survey among potential employers for developing a curriculum in public health nutrition.

    Science.gov (United States)

    Torheim, Liv E; Granli, Gry I; Barikmo, Ingrid; Oshaug, Arne

    2009-08-01

    To describe which functions potential employers of public health nutritionists in Norway find important for a person trained in public health nutrition to be able to carry out. Further, to illustrate how the findings were used in the development of a curriculum for a bachelor in public health nutrition at Akershus University College. A non-random, cross-sectional survey using a questionnaire with both pre-coded and open-ended questions. Ninety-one establishments working in various fields more or less related to nutrition responded (response rate of 45 %). Local offices of the Norwegian Food Safety Authority were over-represented among respondents. Functions related to communication and food and nutrition laws and regulations were most frequently rated as important by the respondents. Functions in nutrition research, project work and policy and planning were also regarded important by more than half of the respondents. The priorities of the potential employers together with the additional comments and suggestions were taken into account when a new curriculum on public health nutrition was developed. The assessment of functions prioritized by employers of public health nutritionists gave a valuable input for developing a new curriculum in public health nutrition. It reflected the challenges of the real world that public health nutritionists will work in and therefore helped making the curriculum potentially more relevant.

  6. In vivo evaluation of the potential neurotoxicity of aerosols released from mechanical stress of nano-TiO2 additived paints in mice chronically exposed by inhalation

    Science.gov (United States)

    Manixay, S.; Delaby, S.; Gaie-Levrel, F.; Wiart, M.; Motzkus, C.; Bencsik, A.

    2017-06-01

    Engineered Nanomaterials (ENM) provide technical and specific benefits due to their physical-chemical properties at the nanometer scale. For instance, many ENM are used to improve products in the building industry. Nanoscaled titanium dioxide (TiO2) is one of the most used ENM in this industry. Incorporated in different matrix, cement, glass, paints… TiO2 nanoparticles (NPs) provide the final product with anti-UV, air purification and self-cleaning properties, thanks to their photocatalytic activity. However, ageing processes of such products, as photocatalytic paints, during a mechanical stress have been shown to release TiO2 NPs from this matrix associated with sanding dust. Thus, workers who sand painted walls could be exposed to TiO2 NPs through inhalation. As inhalation may lead to a translocation of particulate matter to the brain via olfactory or trigeminal nerves, there is an urgent need for evaluating a potential neurotoxicity. In order to provide new knowledge on this topic, we developed a dedicated experimental set-up using a rodent model exposed via inhalation. The aerosol released from a mechanical stress of photocatalytic paints containing TiO2 NPs was characterized and coupled to an exposition chamber containing group of mice free to move and chronically exposed (2 hours per day for 5 days a week during 8 weeks).

  7. In vivo evaluation of the potential neurotoxicity of aerosols released from mechanical stress of nano-TiO2 additived paints in mice chronically exposed by inhalation

    International Nuclear Information System (INIS)

    Manixay, S; Bencsik, A; Delaby, S; Gaie-Levrel, F; Wiart, M; Motzkus, C

    2017-01-01

    Engineered Nanomaterials (ENM) provide technical and specific benefits due to their physical-chemical properties at the nanometer scale. For instance, many ENM are used to improve products in the building industry. Nanoscaled titanium dioxide (TiO 2 ) is one of the most used ENM in this industry. Incorporated in different matrix, cement, glass, paints… TiO 2 nanoparticles (NPs) provide the final product with anti-UV, air purification and self-cleaning properties, thanks to their photocatalytic activity. However, ageing processes of such products, as photocatalytic paints, during a mechanical stress have been shown to release TiO 2 NPs from this matrix associated with sanding dust. Thus, workers who sand painted walls could be exposed to TiO 2 NPs through inhalation. As inhalation may lead to a translocation of particulate matter to the brain via olfactory or trigeminal nerves, there is an urgent need for evaluating a potential neurotoxicity. In order to provide new knowledge on this topic, we developed a dedicated experimental set-up using a rodent model exposed via inhalation. The aerosol released from a mechanical stress of photocatalytic paints containing TiO 2 NPs was characterized and coupled to an exposition chamber containing group of mice free to move and chronically exposed (2 hours per day for 5 days a week during 8 weeks). (paper)

  8. An Empirical Evaluation Of The Potential Of Public E-Procurement To Reduce Corruption

    Directory of Open Access Journals (Sweden)

    Arjun Neupane

    2014-06-01

    Full Text Available One of the significant potential benefits of e-procurement technology is reducing opportunities for corruption in public procurement processes. The authors identified anti-corruption capabilities of e-procurement through an extensive literature review and a theoretical model representing the impact of three latent variables: monopoly of power, information asymmetry, and transparency and accountability upon the dependent variable, the intent-to-adopt e-procurement. This research was guided by the Principal-Agent theory and collected the perceptions of 46 government officers of the potential of public e-procurement to reduce corruption in public procurement processes. Results were analysed using the Partial Least Squares Structural Equation Modeling (PLS-SEM approach. The findings suggest that the intent-to-adopt e-procurement has a positive and significant relationship with the independent variables that might inform developing countries in strategies to combat corruption in public procurement.

  9. Rethinking Potentials of Public Space and its Management Through Placemaking in Kuala Lumpur

    Directory of Open Access Journals (Sweden)

    Sulaiman Normah

    2016-01-01

    Full Text Available Public space takes many spatial forms, including parks, the streets, sidewalks and footpaths that connect an edge of a space between buildings or roadsides, hence are important spaces in an urban setting. In a city context, the public space frames the city image. Kuala Lumpur’s public spaces are typically made up of shopping streets. It allows an ambivalent space that encourages more activities and interactions through the continuity of the street. For that reason, street that brings out life and movement in an urban space is an ideal type of street. In maintaining public spaces and reinventing it, placemaking is a quest for engagement tool to help strengthening legal frameworks in order to protect the public space which is seen viable at a city level. This paper therefore, explores the potentials of public spaces and its management. It applies the case study method by means of investigating two areas in the city encompassing similar characteristics. Generally, the research is designed to test the theoretical framework in managing the public space and its key dimensions in shaping the quality of public space. The researcher then synthesizes the broad range of development of placemaking and the changing uses of public space. The findings will advance further understanding of a suitable application thus intensify the legal framework that shapes the quality of space and its management.

  10. Harnessing the Potential to Quantify Public Preferences for Healthcare Priorities through Citizens’ Juries

    Directory of Open Access Journals (Sweden)

    Jennifer A. Whitty

    2014-07-01

    Full Text Available Despite progress towards greater public engagement, questions about the optimal approach to access public preferences remain unanswered. We review two increasingly popular methods for engaging the public in healthcare priority-setting and determining their preferences; the Citizens’ Jury (CJ and Discrete Choice Experiment (DCE. We discuss the theoretical framework from which each method is derived, its application in healthcare, and critique the information it can provide for decision-makers. We conclude that combining deliberation of an informed public via CJs and quantification of preferences using DCE methods, whilst it remains to be tested as an approach to engaging the public in priority-setting, could potentially achieve much richer information than the application of either method in isolation.

  11. The potential for research-based information in public health: Identifying unrecognised information needs

    Directory of Open Access Journals (Sweden)

    Forsetlund Louise

    2001-01-01

    Full Text Available Abstract Objective To explore whether there is a potential for greater use of research-based information in public health practice in a local setting. Secondly, if research-based information is relevant, to explore the extent to which this generates questioning behaviour. Design Qualitative study using focus group discussions, observation and interviews. Setting Public health practices in Norway. Participants 52 public health practitioners. Results In general, the public health practitioners had a positive attitude towards research-based information, but believed that they had few cases requiring this type of information. They did say, however, that there might be a potential for greater use. During five focus groups and six observation days we identified 28 questions/cases where it would have been appropriate to seek out research evidence according to our definition. Three of the public health practitioners identified three of these 28 cases as questions for which research-based information could have been relevant. This gap is interpreted as representing unrecognised information needs. Conclusions There is an unrealised potential in public health practice for more frequent and extensive use of research-based information. The practitioners did not appear to reflect on the need for scientific information when faced with new cases and few questions of this type were generated.

  12. Potential load reductions on megawatt turbines exposed to wakes using individual-pitch wake compensator and trailing-edge flaps

    DEFF Research Database (Denmark)

    Markou, Helen; Andersen, Peter Bjørn; Larsen, Gunner Chr.

    2011-01-01

    that typically focus on either load or power prediction. As a consequence, the wake affected inflow field generated by the DWM formulation opens for control strategies for the individual turbine. Two different control approaches for load reduction on the individual turbines are implemented in the multi-body aero-servo-elastic...... tool HAWC2, developed at Risø-DTU in Denmark, and their potential load reduction capabilities compared: (1) full-blade ‘individual-pitch controllers’ acting as wake compensators and (2) controllers using trailing-edge flaps. Information on the wake inflow conditions, induced by upstream turbines...... for the loading conditions of the individual turbines in the farm. The dynamic wake meandering model (DWM) is believed to capture the essential physics of the wake problem, and thus, both load and production aspects can be predicted, which is contrary to the traditional engineering wake prediction methods...

  13. Assessment of female reproductive endpoints in Sprague-Dawley rats developmentally exposed to Diuron: potential ovary toxicity.

    Science.gov (United States)

    Grassi, Tony Fernando; Guerra, Marina Trevisan; Perobelli, Juliana Elaine; de Toledo, Fabíola Choqueta; da Silva, Denise Salioni; De Grava Kempinas, Wilma; Barbisan, Luís Fernando

    2011-10-01

    Diuron is widely used in agriculture but its deleterious effects on the reproductive system and mammary gland are still poorly understood. This study evaluated whether early-life-stage exposure to Diuron alters puberty onset or susceptibility to mammary carcinogenesis in female Sprague-Dawley rats. Pregnant rats received basal diet or diet containing Diuron at 500, 750, and 1,250 ppm, from gestational day 12 to the end of lactation (postnatal day 21 [PND21]). After weaning, female offspring continued receiving basal diet or diet containing Diuron until PND 51. At PND 51, female Sprague-Dawley offspring received a single dose of 50 mg/kg b.w. of 7,12-dimethylbenz(a)anthracene (DMBA) for initiation of mammary carcinogenesis. The animals were sacrificed on PND 51, 75, and 226 to 233 (week 25) for mammary gland morphology, reproductive organs and tumor analysis, respectively. There were no significant differences among groups on vaginal opening, estrous cycle, mammary morphology, or carcinogenesis. However, reductions in ovary weight and corpora lutea were observed at PND 75 in the group treated with Diuron at 1,250 ppm. The findings suggesting that Diuron exposure (1,250 ppm) may have been potentially toxic to the ovaries. © 2011 Wiley Periodicals, Inc.

  14. Kidney function and blood pressure in preschool-aged children exposed to cadmium and arsenic - potential alleviation by selenium

    Energy Technology Data Exchange (ETDEWEB)

    Skröder, Helena [Unit of Metals and Health, Institute of Environmental Medicine, Karolinska Institutet, Stockholm (Sweden); Hawkesworth, Sophie [Medical Research Council (MRC), International Nutrition Group, London School of Hygiene and Tropical Medicine, London, UK. (United Kingdom); Kippler, Maria [Unit of Metals and Health, Institute of Environmental Medicine, Karolinska Institutet, Stockholm (Sweden); El Arifeen, Shams [International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka (Bangladesh); Wagatsuma, Yukiko [Department of Clinical Trial and Clinical Epidemiology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan. (Japan); Moore, Sophie E. [MRC Human Nutrition Research, Cambridge (United Kingdom); Vahter, Marie, E-mail: marie.vahter@ki.se [Unit of Metals and Health, Institute of Environmental Medicine, Karolinska Institutet, Stockholm (Sweden)

    2015-07-15

    Background: Early-life exposure to toxic compounds may cause long-lasting health effects, but few studies have investigated effects of childhood exposure to nephrotoxic metals on kidney and cardiovascular function. Objectives: To assess effects of exposure to arsenic and cadmium on kidney function and blood pressure in pre-school-aged children, and potential protection by selenium. Methods: This cross-sectional study was part of the 4.5 years of age (range: 4.4–5.4 years) follow-up of the children from a supplementation trial in pregnancy (MINIMat) in rural Bangladesh, and nested studies on early-life metal exposures. Exposure to arsenic, cadmium and selenium from food and drinking water was assessed by concentrations in children's urine, measured by ICP-MS. Kidney function was assessed by the estimated glomerular filtration rate (eGFR, n=1106), calculated from serum cystatin C, and by kidney volume, measured by ultrasound (n=375). Systolic and diastolic blood pressure was measured (n=1356) after five minutes rest. Results: Multivariable-adjusted regression analyzes showed that exposure to cadmium, but not arsenic, was inversely associated with eGFR, particularly in girls. A 0.5 µg/L increase in urinary cadmium among the girls (above spline knot at 0.12) was associated with a decrease in eGFR of 2.6 ml/min/1.73 m{sup 2}, corresponding to 0.2SD (p=0.022). A slightly weaker inverse association with cadmium was also indicated for kidney volume, but no significant associations were found with blood pressure. Stratifying on children's urinary selenium (below or above median of 12.6 µg/L) showed a three times stronger inverse association of U-Cd with eGFR (all children) in the lower selenium stratum (B=−2.8; 95% CI: −5.5, −0.20; p=0.035), compared to those with higher selenium (B=−0.79; 95% CI: −3.0, 1.4; p=0.49). Conclusions: Childhood cadmium exposure seems to adversely affect kidney function, but not blood pressure, in this population of young

  15. Kidney function and blood pressure in preschool-aged children exposed to cadmium and arsenic - potential alleviation by selenium

    International Nuclear Information System (INIS)

    Skröder, Helena; Hawkesworth, Sophie; Kippler, Maria; El Arifeen, Shams; Wagatsuma, Yukiko; Moore, Sophie E.; Vahter, Marie

    2015-01-01

    Background: Early-life exposure to toxic compounds may cause long-lasting health effects, but few studies have investigated effects of childhood exposure to nephrotoxic metals on kidney and cardiovascular function. Objectives: To assess effects of exposure to arsenic and cadmium on kidney function and blood pressure in pre-school-aged children, and potential protection by selenium. Methods: This cross-sectional study was part of the 4.5 years of age (range: 4.4–5.4 years) follow-up of the children from a supplementation trial in pregnancy (MINIMat) in rural Bangladesh, and nested studies on early-life metal exposures. Exposure to arsenic, cadmium and selenium from food and drinking water was assessed by concentrations in children's urine, measured by ICP-MS. Kidney function was assessed by the estimated glomerular filtration rate (eGFR, n=1106), calculated from serum cystatin C, and by kidney volume, measured by ultrasound (n=375). Systolic and diastolic blood pressure was measured (n=1356) after five minutes rest. Results: Multivariable-adjusted regression analyzes showed that exposure to cadmium, but not arsenic, was inversely associated with eGFR, particularly in girls. A 0.5 µg/L increase in urinary cadmium among the girls (above spline knot at 0.12) was associated with a decrease in eGFR of 2.6 ml/min/1.73 m 2 , corresponding to 0.2SD (p=0.022). A slightly weaker inverse association with cadmium was also indicated for kidney volume, but no significant associations were found with blood pressure. Stratifying on children's urinary selenium (below or above median of 12.6 µg/L) showed a three times stronger inverse association of U-Cd with eGFR (all children) in the lower selenium stratum (B=−2.8; 95% CI: −5.5, −0.20; p=0.035), compared to those with higher selenium (B=−0.79; 95% CI: −3.0, 1.4; p=0.49). Conclusions: Childhood cadmium exposure seems to adversely affect kidney function, but not blood pressure, in this population of young

  16. Mortality (1968-2008) in a French cohort of uranium enrichment workers potentially exposed to rapidly soluble uranium compounds.

    Science.gov (United States)

    Zhivin, Sergey; Guseva Canu, Irina; Samson, Eric; Laurent, Olivier; Grellier, James; Collomb, Philippe; Zablotska, Lydia B; Laurier, Dominique

    2016-03-01

    Until recently, enrichment of uranium for civil and military purposes in France was carried out by gaseous diffusion using rapidly soluble uranium compounds. We analysed the relationship between exposure to soluble uranium compounds and exposure to external γ-radiation and mortality in a cohort of 4688 French uranium enrichment workers who were employed between 1964 and 2006. Data on individual annual exposure to radiological and non-radiological hazards were collected for workers of the AREVA NC, CEA and Eurodif uranium enrichment plants from job-exposure matrixes and external dosimetry records, differentiating between natural, enriched and depleted uranium. Cause-specific mortality was compared with the French general population via standardised mortality ratios (SMR), and was analysed via Poisson regression using log-linear and linear excess relative risk models. Over the period of follow-up, 131 161 person-years at risk were accrued and 21% of the subjects had died. A strong healthy worker effect was observed: all causes SMR=0.69, 95% CI 0.65 to 0.74. SMR for pleural cancer was significantly increased (2.3, 95% CI 1.06 to 4.4), but was only based on nine cases. Internal uranium and external γ-radiation exposures were not significantly associated with any cause of mortality. This is the first study of French uranium enrichment workers. Although limited in statistical power, further follow-up of this cohort, estimation of internal uranium doses and pooling with similar cohorts should elucidate potential risks associated with exposure to soluble uranium compounds. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  17. Increased nitration and carbonylation of proteins in MRL +/+ mice exposed to trichloroethene: Potential role of protein oxidation in autoimmunity

    International Nuclear Information System (INIS)

    Wang Gangduo; Wang Jianling; Ma Huaxian; Khan, M. Firoze

    2009-01-01

    Even though reactive oxygen and nitrogen species (RONS) are implicated as mediators of autoimmune diseases (ADs), little is known about contribution of protein oxidation (carbonylation and nitration) in the pathogenesis of such diseases. The focus of this study was, therefore, to establish a link between protein oxidation and induction and/or exacerbation of autoimmunity. To achieve this, female MRL +/+ mice were treated with trichloroethene (TCE), an environmental contaminant known to induce autoimmune response, for 6 or 12 weeks (10 mmol/kg, i.p., every 4 th day). TCE treatment resulted in significantly increased formation of nitrotyrosine (NT) and induction of iNOS in the serum at both 6 and 12 weeks of treatment, but the response was greater at 12 weeks. Likewise, TCE treatment led to greater NT formation, and iNOS protein and mRNA expression in the livers and kidneys. Moreover, TCE treatment also caused significant increases (∼3 fold) in serum protein carbonyls (a marker of protein oxidation) at both 6 and 12 weeks. Significantly increased protein carbonyls were also observed in the livers and kidneys (2.1 and 1.3 fold, respectively) at 6 weeks, and to a greater extent at 12 weeks (3.5 and 2.1 fold, respectively) following TCE treatment. The increases in TCE-induced protein oxidation (carbonylation and nitration) were associated with significant increases in Th1 specific cytokine (IL-2, IFN-γ) release into splenocyte cultures. These results suggest an association between protein oxidation and induction/exacerbation of autoimmune response. The results present a potential mechanism by which oxidatively modified proteins could contribute to TCE-induced autoimmune response and necessitates further investigations for clearly establishing the role of protein oxidation in the pathogenesis of ADs.

  18. Pollen lipidomics: lipid profiling exposes a notable diversity in 22 allergenic pollen and potential biomarkers of the allergic immune response.

    Directory of Open Access Journals (Sweden)

    Mohamed Elfatih H Bashir

    Full Text Available BACKGROUND/AIM: Pollen grains are the male gametophytes that deliver sperm cells to female gametophytes during sexual reproduction of higher plants. Pollen is a major source of aeroallergens and environmental antigens. The pollen coat harbors a plethora of lipids that are required for pollen hydration, germination, and penetration of the stigma by pollen tubes. In addition to proteins, pollen displays a wide array of lipids that interact with the human immune system. Prior searches for pollen allergens have focused on the identification of intracellular allergenic proteins, but have largely overlooked much of the extracellular pollen matrix, a region where the majority of lipid molecules reside. Lipid antigens have attracted attention for their potent immunoregulatory effects. By being in close proximity to allergenic proteins on the pollen surface when they interact with host cells, lipids could modify the antigenic properties of proteins. METHODOLOGY/PRINCIPAL FINDINGS: We performed a comparative pollen lipid profiling of 22 commonly allergenic plant species by the use of gas chromatography-mass spectroscopy, followed by detailed data mining and statistical analysis. Three experiments compared pollen lipid profiles. We built a database library of the pollen lipids by matching acquired pollen-lipid mass spectra and retention times with the NIST/EPA/NIH mass-spectral library. We detected, identified, and relatively quantified more than 106 lipid molecular species including fatty acids, n-alkanes, fatty alcohols, and sterols. Pollen-derived lipids stimulation up-regulate cytokines expression of dendritic and natural killer T cells co-culture. CONCLUSIONS/SIGNIFICANCE: Here we report on a lipidomic analysis of pollen lipids that can serve as a database for identifying potential lipid antigens and/or novel candidate molecules involved in allergy. The database provides a resource that facilitates studies on the role of lipids in the

  19. Safeguards decision making in the public and regulatory environment, and the potential role of quantitative approaches

    International Nuclear Information System (INIS)

    Sherr, T.S.

    1981-01-01

    This paper briefly examines the nature of the safeguards program's objectives and constraints, and the inherent limitations on comprehensive quantification. It discusses the nature of the public and regulatory processes employed in safeguards decision making, and examines their implications regarding the potential role of quantitative approaches to safeguards policy and operational decision making

  20. The Internet and Generalized Functions of the Public Sphere: Transformative Potentials From a Comparative Perspective

    Directory of Open Access Journals (Sweden)

    Adrian Rauchfleisch

    2016-04-01

    Full Text Available Almost since the advent of the Internet, there has been great interest in analyzing and understanding online communication from the perspective of public sphere theory. The question of whether the properties of the Internet and, specifically, social media actually contribute to the public sphere is the matter of ongoing and somewhat heated scientific debate. The aim of the article is twofold. First, we propose a hierarchical model of generalized functions of public sphere. On a theoretical level, we interweave different strands of thought on the public sphere, and the resulting model is more inclusive and less rigid than each of those strands on their own. We identify four generalized functions: identity building, agenda-setting, control and criticism, and deliberation. The Internet does not contribute equally to these functions and we evaluate the impact of the Internet on each of these functions as a diminishing marginal utility. Second, we empirically explore the plausibility of our model in a global comparative analysis with focus on the Internet. With the help of macro-level variables which indicate the structural preconditions for a public sphere, we identify the highest possible function of the public sphere for each country to which the Internet can potentially contribute. Based on this approach, future research can be contextualized: case-study-based research can plausibly articulate expectations regarding the impact of the Internet on the public sphere.

  1. The potential economic and environmental impact of a Public Benefit Fund in Louisiana

    International Nuclear Information System (INIS)

    Kaiser, M.J.; Pulsipher, A.G.; Baumann, R.H.

    2004-01-01

    Public Benefit Fund programs are one approach to provide energy assistance to low-income households placed at risk in a competitive electric industry. The purpose of this paper is to assess the potential economic and environmental impact of a proposed Public Benefit Fund for the state of Louisiana. The 'best available' model to estimate the relationship between the cost of Public Benefit Fund programs and the benefits delivered by its implementation would be based on an evaluation of existent energy conservation and weatherization programs in the state, but unfortunately, such an evaluation has not been previously performed and so the 'next best' analytic model was employed. The impact of a Public Benefit Fund on energy savings and environmental consequences is assessed through a simulation model and input-output analysis. The model developed is based on publicly available data and infer results under a reasonable assumption set. The model structure and system assumptions of the Public Benefit Fund program are described, realistic policy alternatives are examined--including cost-ceiling, variable funding, and target group strategies--and the limitations of the analysis are outlined

  2. The potential economic and environmental impact of a Public Benefit Fund in Louisiana

    International Nuclear Information System (INIS)

    Kaiser, Mark J.; Pulsipher, Allan G.; Baumann, Robert H.

    2004-01-01

    Public Benefit Fund programs are one approach to provide energy assistance to low-income households placed at risk in a competitive electric industry. The purpose of this paper is to assess the potential economic and environmental impact of a proposed Public Benefit Fund for the state of Louisiana. The 'best available' model to estimate the relationship between the cost of Public Benefit Fund programs and the benefits delivered by its implementation would be based on an evaluation of existent energy conservation and weatherization programs in the state, but unfortunately, such an evaluation has not been previously performed and so the 'next best' analytic model was employed. The impact of a Public Benefit Fund on energy savings and environmental consequences is assessed through a simulation model and input-output analysis. The model developed is based on publicly available data and infer results under a reasonable assumption set. The model structure and system assumptions of the Public Benefit Fund program are described, realistic policy alternatives are examined, including cost-ceiling, variable funding, and target group strategies, and the limitations of the analysis are outlined. (Author)

  3. Detection of T-2 mycotoxin metabolites in urines of exposed rats. Comparison of a potentially fieldable kit with a laboratory assay. Interim report

    Energy Technology Data Exchange (ETDEWEB)

    Hewetson, J.F.; Wannemacher, R.W.; Hawley, R.J.

    1988-03-09

    Rapid methods to detect toxin exposure have been a concern of the Army since the reported use of T-2 mycotoxin as a biological warfare agent in Southeast Asia and Afghanistan. T-2 toxin was included in an exploratory development program of rapid identification systems for biological agents sponsored by the United States Army Medical Materiel Development Activity. Reported here is evidence of T-2W exposure in urines collected up to 2 weeks after rats were exposed to a sublethal dose of T-2 toxin. A laboratory radioimmunoassay (RIA) using polyclonal antibody was used to assay the urines for HT-2 or T-2 tetraol. The sensitivity of the RIA for HT-2 was 5 ng/ml and 50 ng/ml for T-2 tetraol. Some of the urines were assayed in parallel with a potentially fieldable enzyme-linked immunoassay (ELISA) developed for T-2 with a monoclonal antibody that cross reacts with HT-2.

  4. Market potential and growth areas of public utilities. Electromobility; Marktpotenzial und Wachstumsfeld fuer Energieversorger. Elektromobilitaet

    Energy Technology Data Exchange (ETDEWEB)

    Lueers, Thomas [Homburg und Partner, Mannheim (Germany). Kompetenzzentrum Energy/Utilities; Hanitsch, Kai [Homburg und Partner, Mannheim (Germany)

    2010-11-15

    The automobile industry is in full transition. All manufacturers are working on new drive concepts that meet the increasingly rigid emission specifications. Electric power is favoured as an energy source for the future, which gets public utilities interested in teh attractivity of this growing market. Accurate knowledge of the market potential generated by electromobility provides a basis for a targeted and successful marketing strategy. (orig.)

  5. Research in the fields of medicine in Slovenia – research potential, funding, and publications

    Directory of Open Access Journals (Sweden)

    Stojan Pečlin

    2012-09-01

    Conclusions: The size of the human research potential in the fields of medicine in Slovenia is modest. The majority of researchers are also engaged in medical practice and education. Consequently, funds from public sources for research per researcher are low. Research fields of medicine primarly require an increase in human research resources, which can then provide a basis for a rise in funding and the impact of its research results becoming comparable to the EU and world averages.

  6. The Potential Return on Public Investment in Detecting Adverse Drug Effects.

    Science.gov (United States)

    Huybrechts, Krista F; Desai, Rishi J; Park, Moa; Gagne, Joshua J; Najafzadeh, Mehdi; Avorn, Jerry

    2017-06-01

    Many countries lack fully functional pharmacovigilance programs, and public budgets allocated to pharmacovigilance in industrialized countries remain low due to resource constraints and competing priorities. Using 3 case examples, we sought to estimate the public health and economic benefits resulting from public investment in active pharmacovigilance programs to detect adverse drug effects. We assessed 3 examples in which early signals of safety hazards were not adequately recognized, resulting in continued exposure of a large number of patients to these drugs when safer and effective alternative treatments were available. The drug examples studied were rofecoxib, cerivastatin, and troglitazone. Using an individual patient simulation model and the health care system perspective, we estimated the potential costs that could have been averted by early systematic detection of safety hazards through the implementation of active surveillance programs. We found that earlier drug withdrawal made possible by active safety surveillance would most likely have resulted in savings in direct medical costs of $773-$884 million for rofecoxib, $3-$10 million for cerivastatin, and $38-$63 million for troglitazone in the United States through the prevention of adverse events. By contrast, the yearly public investment in Food and Drug Administration initiated population-based pharmacovigilance activities in the United States is about $42.5 million at present. These examples illustrate a critical and economically justifiable role for active adverse effect surveillance in protecting the health of the public.

  7. Stenotrophomonas maltophilia isolated from patients exposed to invasive devices in a university hospital in Argentina: molecular typing, susceptibility and detection of potential virulence factors.

    Science.gov (United States)

    Alcaraz, Eliana; Garcia, Carlos; Papalia, Mariana; Vay, Carlos; Friedman, Laura; Passerini de Rossi, Beatriz

    2018-05-25

    The aim of this work was to investigate the presence of selected potential virulence factors, susceptibility and clonal relatedness among 63 Stenotrophomonas maltophilia isolates recovered from patients exposed to invasive devices in a university hospital in Argentina between January 2004 and August 2012. Genetic relatedness was assessed by enterobacterial repetitive intergenic consensus PCR (ERIC-PCR) and pulsed-field gel electrophoresis (PFGE). Isolates were characterized by antimicrobial resistance, the presence and/or expression of potential virulence determinants, and virulence in the Galleria mellonella model.Results/Key findings. ERIC-PCR generated 52 fingerprints, and PFGE added another pattern. Resistance to trimethoprim-sulfamethoxazole (6.35 %), levofloxacin (9.52 %) and ciprofloxacin (23.80 %) was detected. All isolates were susceptible to minocycline. All isolates were lipase, protease and siderophore producers, while all but Sm61 formed biofilms. However, 11/63 isolates did not amplify the major extracellular protease-coding gene (stmPr1). Sm61 is an stmPr1-negative isolate, and showed (as did Sm13 and the reference strain K279a) strong proteolysis and siderophore production, and high resistance to hydrogen peroxide. The three isolates were virulent in the G. mellonella model, while Sm10, a low-resistance hydrogen peroxide stmPr1-negative isolate, and weak proteolysis and siderophore producer, was not virulent. This is the first epidemiological study of the clonal relatedness of S. maltophilia clinical isolates in Argentina. Great genomic diversity was observed, and only two small clusters of related S. maltophilia types were found. Minocycline and trimethoprim-sulfamethoxazole were the most active agents. S. maltophilia virulence in the G. mellonella model is multifactorial, and further studies are needed to elucidate the role of each potential virulence factor.

  8. The Ciclovía-Recreativa: A mass-recreational program with public health potential.

    Science.gov (United States)

    Sarmiento, Olga; Torres, Andrea; Jacoby, Enrique; Pratt, Michael; Schmid, Thomas L; Stierling, Gonzalo

    2010-07-01

    The Ciclovía-Recreativa is a free, community-based program in which streets are closed temporarily to motorized transport, allowing access to walkers, runners, rollerbladers, and cyclists only. We assessed existing information about the Ciclovía as a public health strategy and proposed next steps for research and public health practice. We conducted a systematic search of peer-reviewed and other literature, which was complemented by expert interviews and consultation. We reviewed 38 Ciclovías from 11 countries. Most programs (84.2%) take place in urban settings. The programs range from 18-64 events per year (54 + or - 24.6; 52 [mean + or - standard deviation; median]) with events lasting from 2-12 hours (6 + or - 2.4; 6). The length of the streets ranges from 1-121 km (14.6 + or - 22.1; 7), and the estimated number of participants per event ranges from 60-1,000,000 persons (61,203 + or - 186,668; 3810). Seventy-one percent of the programs include physical activity classes and in 89% of the Ciclovías, the streets are connected with parks. Ciclovías have potential for positive public health outcomes, but evidence on their effectiveness is limited. The different stages of new and established programs offer a unique opportunity for transnational studies aimed at assessing their public health impact.

  9. Publication of new results from the INWORKS epidemiological study about the risk of cancer among nuclear industry workers chronically exposed to low ionizing radiation doses

    International Nuclear Information System (INIS)

    2015-01-01

    In this cohort study, 308297 workers in the nuclear industry from France, the United Kingdom, and the United States with detailed monitoring data for external exposure to ionising radiation were linked to death registries. Excess relative rate per Gy of radiation dose for mortality from cancer was estimated. Follow-up encompassed 8.2 million person years. Of 66632 known deaths by the end of follow-up, 17?957 were due to solid cancers. Results suggest a linear increase in the rate of cancer with increasing radiation exposure. The average cumulative colon dose estimated among exposed workers was 20.9 mGy (median 4.1 mGy). The estimated rate of mortality from all cancers excluding leukaemia increased with cumulative dose by 48% per Gy (90% confidence interval 20% to 79%), lagged by 10 years. Similar associations were seen for mortality from all solid cancers (47% (18% to 79%)), and within each country. The estimated association over the dose range of 0-100 mGy was similar in magnitude to that obtained over the entire dose range but less precise. Smoking and occupational asbestos exposure are potential confounders; however, exclusion of deaths from lung cancer and pleural cancer did not affect the estimated association. Despite substantial efforts to characterise the performance of the radiation dosimeters used, the possibility of measurement error remains. The study provides a direct estimate of the association between protracted low dose exposure to ionising radiation and solid cancer mortality. Although high dose rate exposures are thought to be more dangerous than low dose rate exposures, the risk per unit of radiation dose for cancer among radiation workers was similar to estimates derived from studies of Japanese atomic bomb survivors. Quantifying the cancer risks associated with protracted radiation exposures can help strengthen the foundation for radiation protection standards

  10. European veterinary public health specialization: post-graduate training and expectations of potential employers.

    Science.gov (United States)

    Alonso, Silvia; Dürr, Salome; Fahrion, Anna; Harisberger, Myriam; Papadopoulou, Christina; Zimmerli, Urs

    2013-01-01

    Residents of the European College of Veterinary Public Health (ECVPH) carried out a survey to explore the expectations and needs of potential employers of ECVPH diplomates and to assess the extent to which the ECVPH post-graduate training program meets those requirements. An online questionnaire was sent to 707 individuals working for universities, government organizations, and private companies active in the field of public health in 16 countries. Details on the structure and activities of the participants' organizations, their current knowledge of the ECVPH, and potential interest in employing veterinary public health (VPH) experts or hosting internships were collected. Participants were requested to rate 22 relevant competencies according to their importance for VPH professionals exiting the ECVPH training. A total of 138 completed questionnaires were included in the analysis. While generic skills such as "problem solving" and "broad horizon and inter-/multidisciplinary thinking" were consistently given high grades by all participants, the importance ascribed to more specialized skills was less homogeneous. The current ECVPH training more closely complies with the profile sought in academia, which may partly explain the lower employment rate of residents and diplomates within government and industry sectors. The study revealed a lack of awareness of the ECVPH among public health institutions and demonstrated the need for greater promotion of this veterinary specialization within Europe, both in terms of its training capacity and the professional skill-set of its diplomates. This study provides input for a critical revision of the ECVPH curriculum and the design of post-graduate training programs in VPH.

  11. Guinea pig model for evaluating the potential public health risk of swine and avian influenza viruses.

    Directory of Open Access Journals (Sweden)

    Yipeng Sun

    Full Text Available BACKGROUND: The influenza viruses circulating in animals sporadically transmit to humans and pose pandemic threats. Animal models to evaluate the potential public health risk potential of these viruses are needed. METHODOLOGY/PRINCIPAL FINDINGS: We investigated the guinea pig as a mammalian model for the study of the replication and transmission characteristics of selected swine H1N1, H1N2, H3N2 and avian H9N2 influenza viruses, compared to those of pandemic (H1N1 2009 and seasonal human H1N1, H3N2 influenza viruses. The swine and avian influenza viruses investigated were restricted to the respiratory system of guinea pigs and shed at high titers in nasal tracts without prior adaptation, similar to human strains. None of the swine and avian influenza viruses showed transmissibility among guinea pigs; in contrast, pandemic (H1N1 2009 virus transmitted from infected guinea pigs to all animals and seasonal human influenza viruses could also horizontally transmit in guinea pigs. The analysis of the receptor distribution in the guinea pig respiratory tissues by lectin histochemistry indicated that both SAα2,3-Gal and SAα2,6-Gal receptors widely presented in the nasal tract and the trachea, while SAα2,3-Gal receptor was the main receptor in the lung. CONCLUSIONS/SIGNIFICANCE: We propose that the guinea pig could serve as a useful mammalian model to evaluate the potential public health threat of swine and avian influenza viruses.

  12. Potential unintended consequences of smoke-free policies in public places on pregnant women in China.

    Science.gov (United States)

    Yao, Tingting; Lee, Anita H; Mao, Zhengzhong

    2009-08-01

    Smoke-free policies in public places have become more common in China. Little is known, however, about the potential unintended consequences of such policies on pregnant women. The study was conducted in 2006 in Chengdu, China. Nonsmoking pregnant women (N=55) whose husband were smokers participated in a study of their knowledge about secondhand smoke and smoke-free policies, their exposure to secondhand smoke, and their husbands' smoking status at home. This study presents descriptive statistics, analyses based on family income and pregnant women's education level, and the findings of focus group discussions that examined the potential unintended consequences of the smoke-free policies on pregnant women. Exposure to secondhand smoke at home was reported by 69.1% of the pregnant women. Both family income and the education level of the pregnant women had a significant (ppolicies were: (1) increased exposure of pregnant women to secondhand smoke at home; (2) reduced work efficiency; (3) adverse effect on family harmony; and (4) poor air quality at home. Education is needed to increase knowledge of secondhand smoke among smokers and nonsmokers alike. When the smoking location is shifted from public places and workplaces to home, women, and in particular pregnant women, become the victims. Policymakers should recognize such potential unintended consequences and take necessary measures to increase awareness about the harms of secondhand smoke.

  13. Guinea pig model for evaluating the potential public health risk of swine and avian influenza viruses.

    Science.gov (United States)

    Sun, Yipeng; Bi, Yuhai; Pu, Juan; Hu, Yanxin; Wang, Jingjing; Gao, Huijie; Liu, Linqing; Xu, Qi; Tan, Yuanyuan; Liu, Mengda; Guo, Xin; Yang, Hanchun; Liu, Jinhua

    2010-11-23

    The influenza viruses circulating in animals sporadically transmit to humans and pose pandemic threats. Animal models to evaluate the potential public health risk potential of these viruses are needed. We investigated the guinea pig as a mammalian model for the study of the replication and transmission characteristics of selected swine H1N1, H1N2, H3N2 and avian H9N2 influenza viruses, compared to those of pandemic (H1N1) 2009 and seasonal human H1N1, H3N2 influenza viruses. The swine and avian influenza viruses investigated were restricted to the respiratory system of guinea pigs and shed at high titers in nasal tracts without prior adaptation, similar to human strains. None of the swine and avian influenza viruses showed transmissibility among guinea pigs; in contrast, pandemic (H1N1) 2009 virus transmitted from infected guinea pigs to all animals and seasonal human influenza viruses could also horizontally transmit in guinea pigs. The analysis of the receptor distribution in the guinea pig respiratory tissues by lectin histochemistry indicated that both SAα2,3-Gal and SAα2,6-Gal receptors widely presented in the nasal tract and the trachea, while SAα2,3-Gal receptor was the main receptor in the lung. We propose that the guinea pig could serve as a useful mammalian model to evaluate the potential public health threat of swine and avian influenza viruses.

  14. Potential use of Vitellogenin and Zona radiata proteins as biomarkers of endocrine disruption in Peregrine falcon exposed to organochlorine compounds (DDTs, PCBs, PCDDs and PCDFs)

    Energy Technology Data Exchange (ETDEWEB)

    Jimenez, B. [CSIC, Inst. of Organic Chemistry, Madrid (Spain); Mori, G.; Concejero, M.A.; Casini, S.; Fossi, M.C. [Siena Univ. (Italy)

    2004-09-15

    Many different classes of environmental contaminants such as industrial chemicals (e.g. alkylphenols, polychlorinated biphenyls, pesticides, PAHs, polychlorinated dibenzo-p-dioxins, and dibenzofurans), ''can cause adverse effects in the reproductive functions of intact organisms or their progenies, consequent to changes in endocrine functions'' showing a so-called Endocrine disruptor activity. Avian raptor species, such as peregrine falcon (Falco peregrinus) for their peculiar position in the food web are potentially at risk in relation to the accumulation of Persistent Organic Pollutants (POPs) and toxic metals. Recent studies carried out with Peregrine falcon (Falco peregrinus) in Spain reveal a contamination with organochlorine compounds (PCDDs, PCDFs, PCBs and DDTs) which could be responsible of the decrease of successful pairs observed during the last ten years. Thus there is a need to develop sensitive diagnostic monitoring tools for the evaluation of toxicological risk and potential effects on the reproductive function and population dynamic of avian top predator species. Two markers for the detection of EDs effects in oviparous vertebrates are induction of Vitellogenin (Vtg) and Zona Radiata Proteins (ZR). Vtg, a complex phospholipoglycoprotein, is the major egg-yolk protein precursor and is normally synthesized by females in response to estradiol. ZR together with Zona Pellucida (ZP) constitutes in birds part of the eggshell. These proteins (Vtg, ZR and ZP) are normally synthesised in the liver as a response to an estrogen signal given by Estradiol. Males and sexually undifferentiated specimens also have the Vtg and ZR genes but do not express them unless exposed to estrogenic compounds. The main aim of this preliminary study was to develop methods for the detection of Vtg and ZR in plasma obtained from peregrine falcon as a specific biomarker for the evaluation of the effects of EDCs.

  15. Extracting potential bus lines of Customized City Bus Service based on public transport big data

    Science.gov (United States)

    Ren, Yibin; Chen, Ge; Han, Yong; Zheng, Huangcheng

    2016-11-01

    Customized City Bus Service (CCBS) can reduce the traffic congestion and environmental pollution that caused by the increasing in private cars, effectively. This study aims to extract the potential bus lines and each line's passenger density of CCBS by mining the public transport big data. The datasets used in this study are mainly Smart Card Data (SCD) and bus GPS data of Qingdao, China, from October 11th and November 7th 2015. Firstly, we compute the temporal-origin-destination (TOD) of passengers by mining SCD and bus GPS data. Compared with the traditional OD, TOD not only has the spatial location, but also contains the trip's boarding time. Secondly, based on the traditional DBSCAN algorithm, we put forwards an algorithm, named TOD-DBSCAN, combined with the spatial-temporal features of TOD.TOD-DBSCAN is used to cluster the TOD trajectories in peak hours of all working days. Then, we define two variables P and N to describe the possibility and passenger destiny of a potential CCBS line. P is the probability of the CCBS line. And N represents the potential passenger destiny of the line. Lastly, we visualize the potential CCBS lines extracted by our procedure on the map and analyse relationship between potential CCBS lines and the urban spatial structure.

  16. Potential of public transit as a transportation control measure: Case studies

    Energy Technology Data Exchange (ETDEWEB)

    Sillings, M.

    1998-07-01

    This report is the final product of the Clean Air Project of the National Association of Regional Councils/NARC. It documents a nationwide study of transit projects and programs initiated in the wake of the 1990 Clean Air Act Amendments/CAAA and the Intermodal Surface Transportation Efficiency Act of 1991/ISTEA. The study purpose was to assess the experience, limitations, and value of public transit as a potential transportation control measure/TCM, i.e., generates significant air quality benefits by eliminating or reducing emissions from motor vehicles. Four in-depth case studies and six additional projects featured as innovations in transportation are offered as examples investigating the potential of transit as a TCM. These case studies and innovations highlight the efforts of ten metropolitan areas and transit agencies which have succeed in developing and implementing innovative transit strategies.

  17. Hydro power potentials of water distribution networks in public universities: A case study

    Directory of Open Access Journals (Sweden)

    Olufemi Adebola KOYA

    2017-06-01

    Full Text Available Public Universities in Southwestern Nigeria are densely populated student-resident campuses, so that provision of regular potable water and electricity are important, but power supply is not optimally available for all the necessary activities. This study assesses the hydropower potential of the water distribution networks in the Universities, with the view to augmenting the inadequate power supplies. The institutions with water distribution configuration capable of accommodating in-pipe turbine are identified; the hydropower parameters, such as the flow characteristics and the pipe geometry are determined to estimate the water power. Global positioning device is used in estimating the elevations of the distribution reservoirs and the nodal points. The hydropower potential of each location is computed incorporating Lucid® Lift-based spherical turbine in the pipeline. From the analysis, the lean and the peak water power are between 1.92 – 3.30 kW and 3.95 – 7.24 kW, respectively, for reservoir-fed distribution networks; while, a minimum of 0.72 kW is got for pipelines associated with borehole-fed overhead tanks. Possible applications of electricity generation from the water distribution networks of the public universities are recommended.

  18. Tolerance mechanisms in mercury-exposed Chromolaena odorata (l.f. R.M. King et H. Robinson, a potential phytoremediator

    Directory of Open Access Journals (Sweden)

    H J P Alcantara

    2013-10-01

    Full Text Available Chromolaena odorata (L.f. R.M. King et H. Robinson plants were grown in Hoagland’s solutions with 0.00 ppm and 1.00 ppm Hg(NO32. The calcium, magnesium, iron, and sulfur levels in the leaves were found to be not significantly affected by presence of the uptaken Hg2+. The chlorophyll a, chlorophyll b, and total chlorophyll contents of its leaves also remained within normal levels, which may indicate that the photosynthetic machinery of the Hg-exposed C. odorata was unaffected by the presence of Hg2+. The results of the ICP-AES analyses of the Hg2+ contents established the presence of Hg2+ in all the subcellular components obtained from the leaves of the Hg-treated C. odorata plants, and that the ultimate localization of Hg2+ is in the vacuoles. The findings revealed no significant differences in the degree of oxidative injury between the cells from the control and Hg-treated plants, as evidenced by the low lipid peroxidation levels obtained with the TBARS assay. The SH-containing biomolecules that were initially detected through DTNB assay manifested a predominant peak in the RP-HPLC chromatographs of both the control and Hg-treated plants, with their retention times falling within the ranges of GSH, MT, and cysteine standards. However, the concentrations of the GSH- and/or MT-like, Cys-containing biomolecules detected in the leaves of Hg-treated C. odorata plants were ten times higher than those of the control.The findings of this study suggest that the enhanced antioxidative capacity, the production of Hg-binding biomolecules, and the localization of Hg2+ ions ultimately in the vacuoles of the leaves are the mechanisms which bring about Hg2+ tolerance and homeostasis in C. odorata plant. These results indicate that C. odorata is a potentially effective phytoremediator for Hg2+.

  19. Microarray detection and qPCR screening of potential biomarkers of Folsomia candida (Collembola: Isotomidae) exposed to Bt proteins (Cry1Ab and Cry1Ac)

    International Nuclear Information System (INIS)

    Yuan, Yiyang; Krogh, Paul Henning; Bai, Xue; Roelofs, Dick; Chen, Fajun; Zhu-Salzman, Keyan; Liang, Yuyong; Sun, Yucheng; Ge, Feng

    2014-01-01

    The impact of Bt proteins on non-target arthropods is less understood than their effects on target organisms where the mechanism of toxic action is known. Here, we report the effects of two Bt proteins, Cry1Ab and Cry1Ac, on gene expression in the non-target collembolan, Folsomia candida. A customized microarray was used to study gene expression in F. candida specimens that were exposed to Cry1Ab and Cry1Ac. All selected transcripts were subsequently confirmed by qPCR. Eleven transcripts were finally verified, and three of them were annotated. The responses of all eleven transcripts were tested in specimens for both Cry1Ab and Cry1Ac at a series of concentrations. These transcripts were separated into two and three groups for Cry1Ab and Cry1Ac, respectively, depend on their expression levels. However, those eleven transcripts did not respond to the Bt proteins in Bt-rice residues. -- Highlights: • We examined the effects of Bt proteins on gene expression of Folsomia candida. • Eleven transcripts were up-regulated by Bt proteins (Cry1Ab and Cry1Ac). • Only three of the eleven transcripts were annotated. • The responses of 11 transcripts were tested on both Cry1Ab and Cry1Ac. • These transcripts did not respond to the Bt proteins in Bt-rice residues. -- Eleven potential molecular biomarkers of Folsomia candida to Cry1Ab and Cry1Ac were screened by microarray and qPCR analysis

  20. Tolerance mechanisms in mercury-exposed Chromolaena odorata (l.f. R.M. King et H. Robinson, a potential phytoremediator

    Directory of Open Access Journals (Sweden)

    H.J.P. Alcantara

    2013-10-01

    Full Text Available Chromolaena odorata (L.f. R.M. King et H. Robinson plants were grown in Hoagland’s solutions with 0.00 ppm and 1.00 ppm Hg(NO32. The calcium, magnesium, iron, and sulfur levels in the leaves were found to be not significantly affected by presence of the uptaken Hg2+. The chlorophyll a, chlorophyll b, and total chlorophyll contents of its leaves also remained within normal levels, which may indicate that the photosynthetic machinery of the Hg-exposed C. odorata was unaffected by the presence of Hg2+. The results of the ICP-AES analyses of the Hg2+ contents established the presence of Hg2+ in all the subcellular components obtained from the leaves of the Hg-treated C. odorata plants, and that the ultimate localization of Hg2+ is in the vacuoles. The findings revealed no significant differences in the degree of oxidative injury between the cells from the control and Hg-treated plants, as evidenced by the low lipid peroxidation levels obtained with the TBARS assay. The SH-containing biomolecules that were initially detected through DTNB assay manifested a predominant peak in the RP-HPLC chromatographs of both the control and Hg-treated plants, with their retention times falling within the ranges of GSH, MT, and cysteine standards. However, the concentrations of the GSH- and/or MT-like, Cys-containing biomolecules detected in the leaves of Hg-treated C. odorata plants were ten times higher than those of the control. The findings of this study suggest that the enhanced antioxidative capacity, the production of Hg-binding biomolecules, and the localization of Hg2+ ions ultimately in the vacuoles of the leaves are the mechanisms which bring about Hg2+ tolerance and homeostasis in C. odorata plant. These results indicate that C. odorata is a potentially effective phytoremediator for Hg2+.

  1. Potential public health impact of Age-Related Eye Disease Study results: AREDS report no. 11.

    Science.gov (United States)

    Bressler, Neil M; Bressler, Susan B; Congdon, Nathan G; Ferris, Frederick L; Friedman, David S; Klein, Ronald; Lindblad, Anne S; Milton, Roy C; Seddon, Johanna M

    2003-11-01

    To estimate the potential public health impact of the findings of the Age-Related Eye Disease Study (AREDS) on reducing the number of persons developing advanced age-related macular degeneration (AMD) during the next 5 years in the United States. The AREDS clinical trial provides estimates of AMD progression rates and of reduction in risk of developing advanced AMD when a high-dose nutritional supplement of antioxidants and zinc is used. These results are applied to estimates of the US population at risk, to estimate the number of people who would potentially avoid advanced AMD during 5 years if those at risk were to take a supplement such as that used in AREDS. An estimated 8 million persons at least 55 years old in the United States have monocular or binocular intermediate AMD or monocular advanced AMD. They are considered to be at high risk for advanced AMD and are those for whom the AREDS formulation should be considered. Of these people, 1.3 million would develop advanced AMD if no treatment were given to reduce their risk. If all of these people at risk received supplements such as those used in AREDS, more than 300,000 (95% confidence interval, 158,000-487,000) of them would avoid advanced AMD and any associated vision loss during the next 5 years. If people at high risk for advanced AMD received supplements such as those suggested by AREDS results, the potential impact on public health in the United States would be considerable during the next 5 years.

  2. Polish physicians' cooperation with the pharmaceutical industry and its potential impact on public health.

    Directory of Open Access Journals (Sweden)

    Marta Makowska

    Full Text Available This article aims to describe how Polish physicians cooperate with the pharmaceutical industry and show how this relationship may pose a threat to public health.It considers the results of an online survey of 379 physicians. The survey was hosted by surveymonkey.com with links from a Polish physicians' website (Medycyna Praktyczna between 29 October 2013 and 31 December 2013. The sample was purposive, respondents having to be physicians working in Poland.The majority of respondents (96.8% said that they had talked with pharmaceutical sales representatives (PSRs in their practice, with 85% saying that they had had regular contact with them. Despite the existing legal ban in Poland, 35% of respondents admitted that they had usually met with PSRs in their office during working hours. As many as 81.8% of surveyed doctors said that they had taken part in an educational meeting organized by the pharmaceutical industry at least once during the 12 months preceding the study. A majority of the respondents (72.3% said they trusted the information provided by PSRs. Over one third of respondents (36.4% claimed that Polish doctors accepted gifts of a type that they should not accept according to Polish law.The study showed that Polish physicians cooperate in different ways with pharmaceutical companies and have frequent contact with them. This can influence their knowledge and doctors whose knowledge of drugs is based mainly on information from pharmaceutical industry materials may prescribe medicines in a biased way, possibly exposing their patients to sub-optimal treatments and burdening both their patients and the state budget with unnecessary costs. Lack of trust in doctors and pharmaceutical companies have other implications too: there may be a decline of faith in the efficacy of therapy and patients may be encouraged to engage in self-diagnosis and self-treatment. For these reasons it is necessary to increase transparency and strengthen the ethical

  3. Polish physicians' cooperation with the pharmaceutical industry and its potential impact on public health.

    Science.gov (United States)

    Makowska, Marta

    2017-01-01

    This article aims to describe how Polish physicians cooperate with the pharmaceutical industry and show how this relationship may pose a threat to public health. It considers the results of an online survey of 379 physicians. The survey was hosted by surveymonkey.com with links from a Polish physicians' website (Medycyna Praktyczna) between 29 October 2013 and 31 December 2013. The sample was purposive, respondents having to be physicians working in Poland. The majority of respondents (96.8%) said that they had talked with pharmaceutical sales representatives (PSRs) in their practice, with 85% saying that they had had regular contact with them. Despite the existing legal ban in Poland, 35% of respondents admitted that they had usually met with PSRs in their office during working hours. As many as 81.8% of surveyed doctors said that they had taken part in an educational meeting organized by the pharmaceutical industry at least once during the 12 months preceding the study. A majority of the respondents (72.3%) said they trusted the information provided by PSRs. Over one third of respondents (36.4%) claimed that Polish doctors accepted gifts of a type that they should not accept according to Polish law. The study showed that Polish physicians cooperate in different ways with pharmaceutical companies and have frequent contact with them. This can influence their knowledge and doctors whose knowledge of drugs is based mainly on information from pharmaceutical industry materials may prescribe medicines in a biased way, possibly exposing their patients to sub-optimal treatments and burdening both their patients and the state budget with unnecessary costs. Lack of trust in doctors and pharmaceutical companies have other implications too: there may be a decline of faith in the efficacy of therapy and patients may be encouraged to engage in self-diagnosis and self-treatment. For these reasons it is necessary to increase transparency and strengthen the ethical guidelines

  4. Polish physicians’ cooperation with the pharmaceutical industry and its potential impact on public health

    Science.gov (United States)

    2017-01-01

    Objective This article aims to describe how Polish physicians cooperate with the pharmaceutical industry and show how this relationship may pose a threat to public health. Methods It considers the results of an online survey of 379 physicians. The survey was hosted by surveymonkey.com with links from a Polish physicians’ website (Medycyna Praktyczna) between 29 October 2013 and 31 December 2013. The sample was purposive, respondents having to be physicians working in Poland. Results The majority of respondents (96.8%) said that they had talked with pharmaceutical sales representatives (PSRs) in their practice, with 85% saying that they had had regular contact with them. Despite the existing legal ban in Poland, 35% of respondents admitted that they had usually met with PSRs in their office during working hours. As many as 81.8% of surveyed doctors said that they had taken part in an educational meeting organized by the pharmaceutical industry at least once during the 12 months preceding the study. A majority of the respondents (72.3%) said they trusted the information provided by PSRs. Over one third of respondents (36.4%) claimed that Polish doctors accepted gifts of a type that they should not accept according to Polish law. Conclusions The study showed that Polish physicians cooperate in different ways with pharmaceutical companies and have frequent contact with them. This can influence their knowledge and doctors whose knowledge of drugs is based mainly on information from pharmaceutical industry materials may prescribe medicines in a biased way, possibly exposing their patients to sub-optimal treatments and burdening both their patients and the state budget with unnecessary costs. Lack of trust in doctors and pharmaceutical companies have other implications too: there may be a decline of faith in the efficacy of therapy and patients may be encouraged to engage in self-diagnosis and self-treatment. For these reasons it is necessary to increase transparency

  5. Effects of Ascorbic Acid on the Amplitude of Ventral Tegmental Area Field Action Potential in Morphine-Exposed Rats (An Electrophysiology Study

    Directory of Open Access Journals (Sweden)

    K Saadipour

    2010-07-01

    Full Text Available Introduction & Objective: Evidences have indicated that the Ventral Tegmental Area (VTA is the major source of dopamine (DA neurons projecting to cortical and limbic regions involved in cognitive and motivational aspects of addiction. Also, studies have indicated that the Ascorbic acid (vitamin C can reduce the dependency symptoms of opioids such as morphine via effect of activity on dopaminergic neuron in VTA. For this reason, the aim of this study was to assess the effects of ascorbic acid on the amplitude of Ventral Tegmental Area field action potential in morphine-exposed rats. Materials & Methods: Forty male Wistar’s rats were used in this experimental study conducted at Yasuj University of Medical Sciences in 2010. Animals were randomly divided into four groups after electrode implantation and recovery period: 1. No- Vit C and No-Addicted group (nVitC.nA 2. Vit C and No-Addicted group (VitC.nA 3. No- Vit C and Addicted group (nVitCA 4.Vit C and Addicted (VitC.A, The Vit C groups received 500 mg/kg of Vit C during 20 days. For addicted groups morphine was administrated once daily for 20 days. In the 20th day, the field potential recording was accomplished. Two-way ANOVA was used for data analysis followed by the Tukey test for post hoc analysis. Results were considered significant at P < 0.05. Results: This study shows the exposure to morphine declined the power of Delta and Beta bands (p<0.05 and Vit C solely enhance power of Theta and Beta (p<0.05, p<0.001 in VTA nuclei. Furthermore, Vit C could alter power of some bands which were affected by morphine. Therefore it seems that Vit C has an increasing effects on them (p<0.05. Conclusion: Although the effect of Vit C on power of the VTA bands is not well known, but it is supposed that this phenomenon can be related to alteration in activity of dopaminergic neuron in the brain.

  6. Assessing the Potential for Rooftop Rainwater Harvesting from Large Public Institutions

    Directory of Open Access Journals (Sweden)

    Dagnachew Adugna

    2018-02-01

    Full Text Available As in many other cities, urbanization coupled with population growth worsens the water supply problem of Addis Ababa, Ethiopia, with a water supply deficit of 41% in 2016. To investigate the potential contribution of rooftop rainwater harvesting (RWH from large public institutions, 320 such institutions were selected and grouped into 11 categories, from which 25–30% representative 588 rooftops were digitalized and the potential RWH volume computed based on a ten-year rainfall dataset. When comparing the resulting RWH potential with the water consumption, up to 2.3% of the annual, potable water supply can be provided. If reused only within one’s own institution, the self-sufficiency varies from 0.9 to 649%. Non-uniform rainfall patterns add uncertainty to these numbers, since the size of the storage tank becomes critical for coverage in the dry season from October to May. Despite the low replacement potential at the city level, RWH from large institutions will enable a significant volume of potable water to be transferred to localities critically suffering from water shortage. Further, large institutions may demonstrate how RWH can be practiced, thus acting as a frontrunner for the dissemination of RWH to other types of rooftops. To narrow the water supply gap, considering rooftop RWH as an alternative water supply source is recommended. However, the present study assumed that financial constraints to install large sized storage tanks are considered as a possible challenge. Thus, future research is needed to investigate the cost-benefit balance along with the invention of a cheap storage tank as they may affect the potential contribution of RWH from rooftops.

  7. Assessing the Potential for Rooftop Rainwater Harvesting from Large Public Institutions.

    Science.gov (United States)

    Adugna, Dagnachew; Jensen, Marina Bergen; Lemma, Brook; Gebrie, Geremew Sahilu

    2018-02-14

    As in many other cities, urbanization coupled with population growth worsens the water supply problem of Addis Ababa, Ethiopia, with a water supply deficit of 41% in 2016. To investigate the potential contribution of rooftop rainwater harvesting (RWH) from large public institutions, 320 such institutions were selected and grouped into 11 categories, from which 25-30% representative 588 rooftops were digitalized and the potential RWH volume computed based on a ten-year rainfall dataset. When comparing the resulting RWH potential with the water consumption, up to 2.3% of the annual, potable water supply can be provided. If reused only within one's own institution, the self-sufficiency varies from 0.9 to 649%. Non-uniform rainfall patterns add uncertainty to these numbers, since the size of the storage tank becomes critical for coverage in the dry season from October to May. Despite the low replacement potential at the city level, RWH from large institutions will enable a significant volume of potable water to be transferred to localities critically suffering from water shortage. Further, large institutions may demonstrate how RWH can be practiced, thus acting as a frontrunner for the dissemination of RWH to other types of rooftops. To narrow the water supply gap, considering rooftop RWH as an alternative water supply source is recommended. However, the present study assumed that financial constraints to install large sized storage tanks are considered as a possible challenge. Thus, future research is needed to investigate the cost-benefit balance along with the invention of a cheap storage tank as they may affect the potential contribution of RWH from rooftops.

  8. Publicity.

    Science.gov (United States)

    Chisholm, Joan

    Publicity for preschool cooperatives is described. Publicity helps produce financial support for preschool cooperatives. It may take the form of posters, brochures, newsletters, open house, newspaper coverage, and radio and television. Word of mouth and general good will in the community are the best avenues of publicity that a cooperative nursery…

  9. Reducing the potential for conflict between proponents and the public regarding the risks entailed by radioactive waste management facilities

    International Nuclear Information System (INIS)

    Rogers, B.G.

    1984-01-01

    Sources of potential conflict between proponents and the public regarding the risks entailed by radioactive waste management facilities are identified and analyzed. Programs and policies are suggested that could reduce conflict over the siting and operation of such facilities

  10. Legionella spp. in UK composts--a potential public health issue?

    Science.gov (United States)

    Currie, S L; Beattie, T K; Knapp, C W; Lindsay, D S J

    2014-04-01

    Over the past 5 years, a number of cases of legionellosis in Scotland have been associated with compost use; however, studies investigating sources of infection other than water systems remain limited. This study delivers the first comprehensive survey of composts commonly available in the UK for the presence of Legionella species. Twenty-two store-bought composts, one green-waste compost and one home-made compost were tested for Legionella by culture methods on BCYE-α medium, and the findings were confirmed by macrophage infectivity potentiator (mip) speciation. Twenty-two of the samples were retested after an enrichment period of 8 weeks. In total, 15 of 24 composts tested positive for Legionella species, a higher level of contamination than previously seen in Europe. Two isolates of Legionella pneumophila were identified, and Legionella longbeachae serogroup 1 was found to be one of the most commonly isolated species. L. longbeachae infection would not be detected by routine Legionella urinary antigen assay, so such testing should not be used as the sole diagnostic technique in atypical pneumonia cases, particularly where there is an association with compost use. The occurrence of Legionella in over half of the samples tested indicates that compost could pose a public health risk. The addition of general hygiene warnings to compost packages may be beneficial in protecting public health. © 2013 The Authors Clinical Microbiology and Infection © 2013 European Society of Clinical Microbiology and Infectious Diseases.

  11. Physico-Chemical and Bacterial Evaluation of Public and Packaged Drinking Water in Vikarabad, Telangana, India - Potential Public Health Implications.

    Science.gov (United States)

    Rao, Koppula Yadav; Anjum, Mohammad Shakeel; Reddy, Peddireddy Parthasarathi; Monica, Mocherla; Hameed, Irram Abbass; Sagar, Goje Vidya

    2016-05-01

    Humanity highly depends on water and its proper utilization and management. Water has various uses and its use as thirst quenching fluid is the most significant one. To assess physical, chemical, trace metal and bacterial parameters of various public and packaged drinking water samples collected from villages of Vikarabad mandal. Public and packaged drinking water samples collected were analysed for various parameters using American Public Health Association (APHA 18(th) edition 1992) guidelines and the results obtained were compared with bureau of Indian standards for drinking water. Descriptive statistics and Pearson's correlations were done. Among bottled water samples, magnesium in 1 sample was >30mg/litre, nickel in 2 samples was >0.02mg/litre. Among sachet water samples, copper in 1 sample was >0.05mg/litre, nickel in 2 samples was >0.02mg/litre. Among canned water samples, total hardness in 1 sample was >200mg/litre, magnesium in 3 samples was >30mg/litre. In tap water sample, calcium was >75mg/litre, magnesium was >30mg/litre, nickel was >0.02mg/litre. Among public bore well water samples, pH in 1 sample was >8.5, total dissolved solids in 17 samples was >500mg/litre, total alkalinity in 9 samples was >200mg/litre, total hardness in 20 samples was >200mg/litre, calcium in 14 samples was >75mg/litre, fluoride in 1 sample was >1mg/litre, magnesium in 14 samples was >30mg/litre. Total coliform was absent in bottled water, sachet water, canned water, tap water samples. Total Coliform was present but E. coli was absent in 4 public bore well water samples. The MPN per 100 ml in those 4 samples of public bore well water was 50. Physical, chemical, trace metal and bacterial parameters tested in present study showed values greater than acceptable limit for some samples, which can pose serious threat to consumers of that region.

  12. Computational assessment of pregnant woman models exposed to uniform ELF-magnetic fields: compliance with the European current exposure regulations for the general public and occupational exposures at 50 Hz

    International Nuclear Information System (INIS)

    Liorni, Ilaria; Parazzini, Marta; Fiocchi, Serena; Ravazzani, Paolo; Douglas, Mark; Capstick, Myles; Kuster, Niels

    2016-01-01

    The Recommendation 1999/529/EU and the Directive 2013/35/EU suggest limits for both general public and occupational exposures to extremely low-frequency magnetic fields, but without special limits for pregnant women. This study aimed to assess the compliance of pregnant women to the current regulations, when exposed to uniform MF at 50 Hz (100 μT for EU Recommendation and 1 and 6 mT for EU Directive). For general public, exposure of pregnant women and fetus always resulted in compliance with EU Recommendation. For occupational exposures, (1) Electric fields in pregnant women were in compliance with the Directive, with exposure variations due to fetal posture of 40 % in head tissues, (3) Electric fields in fetal CNS tissues of head are above the ICNIRP 2010 limits for general public at 1 mT (in 7 and 9 months gestational age) and at 6 mT (in all gestational ages). (authors)

  13. Proceedings of the Symposium of Medical (Ophthalmic) Surveillance of Personnel Potentially Exposed to Laser Radiation Held on 8-9 September 1982.

    Science.gov (United States)

    1982-01-01

    because of maxillary sinus cancer was exposed to a relatively low-energy pulsed ruby laser in 1964 at a distance of about 150 m. The man reported only a...functionally regardless of the appearance of the retina? The answer, I think, is yes. If we only test for function and do not become distracted by

  14. Potential radiation doses from 1994 Hanford Operations

    Energy Technology Data Exchange (ETDEWEB)

    Soldat, J.K.; Antonio, E.J.

    1995-06-01

    This section of the 1994 Hanford Site Environmental Report summarizes the potential radiation doses to the public from releases originating at the Hanford Site. Members of the public are potentially exposed to low-levels of radiation from these effluents through a variety of pathways. The potential radiation doses to the public were calculated for the hypothetical MEI and for the general public residing within 80 km (50 mi) of the Hanford Site.

  15. Potential radiation doses from 1994 Hanford Operations

    International Nuclear Information System (INIS)

    Soldat, J.K.; Antonio, E.J.

    1995-01-01

    This section of the 1994 Hanford Site Environmental Report summarizes the potential radiation doses to the public from releases originating at the Hanford Site. Members of the public are potentially exposed to low-levels of radiation from these effluents through a variety of pathways. The potential radiation doses to the public were calculated for the hypothetical MEI and for the general public residing within 80 km (50 mi) of the Hanford Site

  16. Potential travel cost saving in urban public-transport networks using smartphone guidance

    Science.gov (United States)

    2018-01-01

    Public transport (PT) is a key element in most major cities around the world. With the development of smartphones, available journey planning information is becoming an integral part of the PT system. Each traveler has specific preferences when undertaking a trip, and these preferences can also be reflected on the smartphone. This paper considers transit assignment in urban public-transport networks in which the passengers receive smartphone-based information containing elements that might influence the travel decisions in relation to line loads, as well as passenger benefits, and the paper discusses the transition from the current widespread choosing approach to a personalized decision-making approach based on smartphone information. The approach associated with smartphone guidance that considers passengers’ preference on travel time, waiting time and transfer is proposed in the process of obtaining his/her preferred route from the potential travel routes generated by the Deep First Search (DFS) method. Two other approaches, based on the scenarios reflecting reality, include passengers with access to no real time information, and passengers that only have access to the arrival time at the platform are used as comparisons. For illustration, the same network proposed by Spiess and Florian is utilized on the experiments in an agent-based model. Two experiments are conducted respectively according to whether each passenger’s choosing method is consistent. As expected, the results in the first experiment showed that the travel for consistent passengers with smartphone guidance was clearly shorter and that it can reduce travel time exceeding 15% and weighted cost exceeding 20%, and the average saved time approximated 3.88 minutes per passenger. The second experiment presented that travel cost, as well as cost savings, gradually decreased by employing smartphone guidance, and the maximum cost savings accounted for 14.2% of the total weighted cost. PMID:29746528

  17. Potential travel cost saving in urban public-transport networks using smartphone guidance.

    Science.gov (United States)

    Song, Cuiying; Guan, Wei; Ma, Jihui

    2018-01-01

    Public transport (PT) is a key element in most major cities around the world. With the development of smartphones, available journey planning information is becoming an integral part of the PT system. Each traveler has specific preferences when undertaking a trip, and these preferences can also be reflected on the smartphone. This paper considers transit assignment in urban public-transport networks in which the passengers receive smartphone-based information containing elements that might influence the travel decisions in relation to line loads, as well as passenger benefits, and the paper discusses the transition from the current widespread choosing approach to a personalized decision-making approach based on smartphone information. The approach associated with smartphone guidance that considers passengers' preference on travel time, waiting time and transfer is proposed in the process of obtaining his/her preferred route from the potential travel routes generated by the Deep First Search (DFS) method. Two other approaches, based on the scenarios reflecting reality, include passengers with access to no real time information, and passengers that only have access to the arrival time at the platform are used as comparisons. For illustration, the same network proposed by Spiess and Florian is utilized on the experiments in an agent-based model. Two experiments are conducted respectively according to whether each passenger's choosing method is consistent. As expected, the results in the first experiment showed that the travel for consistent passengers with smartphone guidance was clearly shorter and that it can reduce travel time exceeding 15% and weighted cost exceeding 20%, and the average saved time approximated 3.88 minutes per passenger. The second experiment presented that travel cost, as well as cost savings, gradually decreased by employing smartphone guidance, and the maximum cost savings accounted for 14.2% of the total weighted cost.

  18. Potential Impacts of Future Climate Change on Regional Air Quality and Public Health over China

    Science.gov (United States)

    Hong, C.; Zhang, Q.; Zhang, Y.; He, K.

    2017-12-01

    Future climate change would affect public health through changing air quality. Climate extremes and poor weather conditions are likely to occur at a higher frequency in China under a changing climate, but the air pollution-related health impacts due to future climate change remain unclear. Here the potential impacts of future climate change on regional air quality and public health over China is projected using a coupling of climate, air quality and epidemiological models. We present the first assessment of China's future air quality in a changing climate under the Representative Concentration Pathway 4.5 (RCP4.5) scenario using the dynamical downscaling technique. In RCP4.5 scenario, we estimate that climate change from 2006-2010 to 2046-2050 is likely to adversely affect air quality covering more than 86% of population and 55% of land area in China, causing an average increase of 3% in O3 and PM2.5 concentrations, which are found to be associated with the warmer climate and the more stable atmosphere. Our estimate of air pollution-related mortality due to climate change in 2050 is 26,000 people per year in China. Of which, the PM2.5-related mortality is 18,700 people per year, and the O3-related mortality is 7,300 people per year. The climate-induced air pollution and health impacts vary spatially. The climate impacts are even more pronounced on the urban areas where is densely populated and polluted. 90% of the health loss is concentrated in 20% of land areas in China. We use a simple statistical analysis method to quantify the contributions of climate extremes and find more intense climate extremes play an important role in climate-induced air pollution-related health impacts. Our results indicate that global climate change will likely alter the level of pollutant management required to meet future air quality targets as well as the efforts to protect public health in China.

  19. The potential role for management of U.S. public lands in greenhouse gas mitigation and climate policy.

    Science.gov (United States)

    Olander, Lydia P; Cooley, David M; Galik, Christopher S

    2012-03-01

    Management of forests, rangelands, and wetlands on public lands, including the restoration of degraded lands, has the potential to increase carbon sequestration or reduce greenhouse gas (GHG) emissions beyond what is occurring today. In this paper we discuss several policy options for increasing GHG mitigation on public lands. These range from an extension of current policy by generating supplemental mitigation on public lands in an effort to meet national emissions reduction goals, to full participation in an offsets market by allowing GHG mitigation on public lands to be sold as offsets either by the overseeing agency or by private contractors. To help place these policy options in context, we briefly review the literature on GHG mitigation and public lands to examine the potential for enhanced mitigation on federal and state public lands in the United States. This potential will be tempered by consideration of the tradeoffs with other uses of public lands, the needs for climate change adaptation, and the effects on other ecosystem services.

  20. Zika Virus and Transgenic Mosquitoes: Potentials of a Public Health Tool

    Directory of Open Access Journals (Sweden)

    Ike Val Iyioke

    2017-01-01

    Full Text Available With transgenic mosquitoes now being deployed as a major solution to the pandemic Zika virus disease, more curious questions have arisen about this public health technology. This essay reviews the philosophical considerations that presaged the development, by WHO, of the genetically modified mosquitoes. It focuses more specifically on the inter-disciplinary approach in formulating the clinical trials process. While it is still early to determine the full merits of this health intervention tool, it is nonetheless timely to examine the rich vein of form that constitutes the clinical trial protocol. I argue that the steps it suggests should be a gold standard for all clinical trial procedures including those that use human subjects and those with both direct and indirect environmental implications. Also, the early signs portend that its application could indeed be widespread. For instance, malaria and dengue fever were the original targets, but now the development of transgenic mosquito technology is deemed a potent option in the fight against Zika virus disease. In addition, this clinical trial protocol has remarkably gone beyond the four pillars of principlism to recognize the possibility that a new technology (such as GMM, can have the potential to simultaneously impact human individuals, the community and the ecosystem in tandem. In “Guidance framework for testing of genetically modified mosquito,” the WHO has set an example that calls for emulation. With the right awareness, biomedical researchers, scholars, policy makers, and students stand to benefit immensely from this reformulated approach.

  1. Potential translational targets revealed by linking mouse grooming behavioral phenotypes to gene expression using public databases.

    Science.gov (United States)

    Roth, Andrew; Kyzar, Evan J; Cachat, Jonathan; Stewart, Adam Michael; Green, Jeremy; Gaikwad, Siddharth; O'Leary, Timothy P; Tabakoff, Boris; Brown, Richard E; Kalueff, Allan V

    2013-01-10

    Rodent self-grooming is an important, evolutionarily conserved behavior, highly sensitive to pharmacological and genetic manipulations. Mice with aberrant grooming phenotypes are currently used to model various human disorders. Therefore, it is critical to understand the biology of grooming behavior, and to assess its translational validity to humans. The present in-silico study used publicly available gene expression and behavioral data obtained from several inbred mouse strains in the open-field, light-dark box, elevated plus- and elevated zero-maze tests. As grooming duration differed between strains, our analysis revealed several candidate genes with significant correlations between gene expression in the brain and grooming duration. The Allen Brain Atlas, STRING, GoMiner and Mouse Genome Informatics databases were used to functionally map and analyze these candidate mouse genes against their human orthologs, assessing the strain ranking of their expression and the regional distribution of expression in the mouse brain. This allowed us to identify an interconnected network of candidate genes (which have expression levels that correlate with grooming behavior), display altered patterns of expression in key brain areas related to grooming, and underlie important functions in the brain. Collectively, our results demonstrate the utility of large-scale, high-throughput data-mining and in-silico modeling for linking genomic and behavioral data, as well as their potential to identify novel neural targets for complex neurobehavioral phenotypes, including grooming. Copyright © 2012 Elsevier Inc. All rights reserved.

  2. NESHAP Area-Specific Dose-Release Factors for Potential Onsite Member-of-the-Public Locations at SRS using CAP88-PC Version 4.0

    Energy Technology Data Exchange (ETDEWEB)

    Trimor, P. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2017-08-09

    The Environmental Protection Agency (EPA) requires the use of the computer model CAP88-PC to estimate the total effective doses (TED) for demonstrating compliance with 40 CFR 61, Subpart H (EPA 2006), the National Emission Standards for Hazardous Air Pollutants (NESHAP) regulations. As such, CAP88 Version 4.0 was used to calculate the receptor dose due to routine atmospheric releases at the Savannah River Site (SRS). For estimation, NESHAP dose-release factors (DRFs) have been supplied to Environmental Compliance and Area Closure Projects (EC&ACP) for many years. DRFs represent the dose to a maximum receptor exposed to 1 Ci of a specified radionuclide being released into the atmosphere. They are periodically updated to include changes in the CAP88 version, input parameter values, site meteorology, and location of the maximally exposed individual (MEI). In this report, the DRFs were calculated for potential radionuclide atmospheric releases from 13 SRS release points. The three potential onsite MEI locations to be evaluated are B-Area, Three Rivers Landfill (TRL), and Savannah River Ecology Lab Conference Center (SRELCC) with TRL’s onsite workers considered as members-of-the-public, and the potential future constructions of dormitories at SRELCC and Barracks at B-Area. Each MEI location was evaluated at a specified compass sector with different area to receptor distances and was conducted for both ground-level and elevated release points. The analysis makes use of area-specific meteorological data (Viner 2014). The resulting DRFs are compared to the 2014 NESHAP offsite MEI DRFs for three operational areas; A-Area, H-Area, and COS for a release rate of 1 Ci of tritium oxide at 0 ft. elevation. CAP88 was executed again using the 2016 NESHAP MEI release rates for 0 and 61 m stack heights to determine the radionuclide dose at TRL from the center-of-site (COS).

  3. Economic Evaluation of a Public Service Potential of a Municipality - Urban Development in Romania

    Directory of Open Access Journals (Sweden)

    Florin Marian BUHOCIU

    2011-11-01

    Full Text Available In Romania there are 13 cities urban growth poles, including the city of Galati. Our research presents the structure of public services as well as a recital of the trade becoming more sectors / public areas and is developing a major commercial component. It is therefore necessary to evaluate both the overall public services, public or private and commercial of the NACE codes. Were identified 15 key activities that provide 90% of all available services for them and presenting the turnover and number of employees. Malfunctions roots in key areas identified were evaluated on the structure and layout in the area of public services. In this way you can calculate specific indicators of public services of such a city, being able to compare their levels with corresponding levels of the same indicators of urban growth pole unite and can also take the best decisions for development near the levels of both types of municipalities in Romania.

  4. Global gene expression in larval zebrafish (Danio rerio) exposed to selective serotonin reuptake inhibitors (fluoxetine and sertraline) reveals unique expression profiles and potential biomarkers of exposure

    International Nuclear Information System (INIS)

    Park, June-Woo; Heah, Tze Ping; Gouffon, Julia S.; Henry, Theodore B.; Sayler, Gary S.

    2012-01-01

    Larval zebrafish (Danio rerio) were exposed (96 h) to selective serotonin reuptake inhibitors (SSRIs) fluoxetine and sertraline and changes in transcriptomes analyzed by Affymetrix GeneChip ® Zebrafish Array were evaluated to enhance understanding of biochemical pathways and differences between these SSRIs. The number of genes differentially expressed after fluoxetine exposure was 288 at 25 μg/L and 131 at 250 μg/L; and after sertraline exposure was 33 at 25 μg/L and 52 at 250 μg/L. Same five genes were differentially regulated in both SSRIs indicating shared molecular pathways. Among these, the gene coding for FK506 binding protein 5, annotated to stress response regulation, was highly down-regulated in all treatments (results confirmed by qRT-PCR). Gene ontology analysis indicated at the gene expression level that regulation of stress response and cholinesterase activities were influenced by these SSRIs, and suggested that changes in transcription of these genes could be used as biomarkers of SSRI exposure. - Highlights: ► Exposure of zebrafish to selective serotonin reuptake inhibitors (SSRIs). ► Fluoxetine and sertraline generate different global gene expression profiles. ► Genes linked to stress response and acetylcholine esterase affected by both SSRIs. - Global gene expression profiles in zebrafish exposed to selective serotonin reuptake inhibitors.

  5. PUBLIC POLICIES AND STRATEGIES TO ENHANCE THE ECONOMIC POTENTIAL OF A COUNTRY . CASE OF MOLDOVA

    Directory of Open Access Journals (Sweden)

    Eugenia BUŞMACHIU

    2012-06-01

    Full Text Available The study of concepts applied in the decision - making process aims to investigate the functioning of mechanisms to develop and implement the central public administration policies. A modern decision - making process includes the whole procedure of decision making: setting the priorities of public policies, choosing options, instruments of public policy implementation, developing and adopting the respective legislative and normative acts, funding to implement these policies, conducting implementation actions and monitoring the impact of public policy decisions. Often the decision - making process in public administration is interpreted as a simple organization of the information and documents circuit. Therefore there arises the need to analyze the concept of decision making and propose solutions to improve it.

  6. Do drug treatment facilities increase clients' exposure to potential neighborhood-level triggers for relapse? A small-area assessment of a large, public treatment system.

    Science.gov (United States)

    Jacobson, Jerry O

    2006-03-01

    Research on drug treatment facility locations has focused narrowly on the issue of geographic proximity to clients. We argue that neighborhood conditions should also enter into the facility location decision and illustrate a formal assessment of neighborhood conditions at facilities in a large, metropolitan area, taking into account conditions clients already face at home. We discuss choice and construction of small-area measures relevant to the drug treatment context, including drug activity, disadvantage, and violence as well as statistical comparisons of clients' home and treatment locations with respect to these measures. Analysis of 22,707 clients discharged from 494 community-based outpatient and residential treatment facilities that received public funds during 1998-2000 in Los Angeles County revealed no significant mean differences between home and treatment neighborhoods. However, up to 20% of clients are exposed to markedly higher levels of disadvantage, violence, or drug activity where they attend treatment than where they live, suggesting that it is not uncommon for treatment locations to increase clients' exposure to potential environmental triggers for relapse. Whereas on average both home and treatment locations exhibit higher levels of these measures than the household locations of the general population, substantial variability in public treatment clients' home neighborhoods calls into question the notion that they hail exclusively from poor, high drug activity areas. Shortcomings of measures available for neighborhood assessment of treatment locations and implications of the findings for other areas of treatment research are also discussed.

  7. Potential Impact of Public Perception on the Transport of Radioactive Material

    International Nuclear Information System (INIS)

    Glenn, K.

    2016-01-01

    In the last 50 years, the transport of radioactive material, with the exception of some used fuel and nuclear waste shipments, has remained in relative obscurity when it comes to the realm of public interest and concern. Only a few shipments out of the millions that take place every year have been the subject of protest or public demonstrations, mostly attributed to anti-nuclear sentiment rather than concern over transportation safety. However, with the advent of the Internet and greater accessibility to information, the public has begun to show greater scrutiny towards the transportation activities associated with the use of nuclear substances. More frequently, the safety of transportation is questioned and debated in the various public fora. The challenge to regulators in years to come will be to continue to assure safety through regulations based on science, knowledge and experience while responding to the public demand for transparency and input without compromising national and international security. Better communication skills will be required by both competent authorities and industry to ensure that the public comprehends what the risks actually are and how they are mitigated. Regulators will have to examine long established and recognized processes to determine if they are still appropriate in the 21 st century, striking a balance between security and the public’s right to know. This paper examines the public interest in two Canadian cases and the related issues. (author)

  8. Potential health impact of switching from car to public transportation when commuting to work.

    Science.gov (United States)

    Morabia, Alfredo; Mirer, Franklin E; Amstislavski, Tashia M; Eisl, Holger M; Werbe-Fuentes, Jordan; Gorczynski, John; Goranson, Chris; Wolff, Mary S; Markowitz, Steven B

    2010-12-01

    We assessed humidity-corrected particulate matter (PM(2.5)) exposure and physical activity (using global positioning system monitors and diaries) among 18 people who commuted by car to Queens College, New York, New York, for 5 days, and then switched to commuting for the next 5 days via public transportation. The PM(2.5) differed little between car and public transportation commutes (1.41 μg/M(3)·min; P = .226). Commuting by public transportation rather than by car increased energy expenditure (+124 kcal/day; P < .001) equivalent to the loss of 1 pound of body fat per 6 weeks.

  9. Exploring potentials of sense-making theory for understanding social processes in public hearing

    DEFF Research Database (Denmark)

    Lyhne, Ivar

    authorities and the public in such planning often characterised by conflict. A sense-making framework is developed based on Karl Weick's theory to investigate how participants at the meeting change their understanding aspects like other actors' opinions and the infrastructure project. Through interviews...... and observations it is shown that participants' senses do not change except from a few aspects. The participants at the meeting thus seem stuck in their positions without interest in being open for other interpretations or arguments. The investigation leads to considerations about the benefit and role...... of such a public meeting and the importance of trust and openness in the social processes in a public hearing....

  10. A high-resolution gene expression atlas of epistasis between gene-specific transcription factors exposes potential mechanisms for genetic interactions.

    Science.gov (United States)

    Sameith, Katrin; Amini, Saman; Groot Koerkamp, Marian J A; van Leenen, Dik; Brok, Mariel; Brabers, Nathalie; Lijnzaad, Philip; van Hooff, Sander R; Benschop, Joris J; Lenstra, Tineke L; Apweiler, Eva; van Wageningen, Sake; Snel, Berend; Holstege, Frank C P; Kemmeren, Patrick

    2015-12-23

    Genetic interactions, or non-additive effects between genes, play a crucial role in many cellular processes and disease. Which mechanisms underlie these genetic interactions has hardly been characterized. Understanding the molecular basis of genetic interactions is crucial in deciphering pathway organization and understanding the relationship between genotype, phenotype and disease. To investigate the nature of genetic interactions between gene-specific transcription factors (GSTFs) in Saccharomyces cerevisiae, we systematically analyzed 72 GSTF pairs by gene expression profiling double and single deletion mutants. These pairs were selected through previously published growth-based genetic interactions as well as through similarity in DNA binding properties. The result is a high-resolution atlas of gene expression-based genetic interactions that provides systems-level insight into GSTF epistasis. The atlas confirms known genetic interactions and exposes new ones. Importantly, the data can be used to investigate mechanisms that underlie individual genetic interactions. Two molecular mechanisms are proposed, "buffering by induced dependency" and "alleviation by derepression". These mechanisms indicate how negative genetic interactions can occur between seemingly unrelated parallel pathways and how positive genetic interactions can indirectly expose parallel rather than same-pathway relationships. The focus on GSTFs is important for understanding the transcription regulatory network of yeast as it uncovers details behind many redundancy relationships, some of which are completely new. In addition, the study provides general insight into the complex nature of epistasis and proposes mechanistic models for genetic interactions, the majority of which do not fall into easily recognizable within- or between-pathway relationships.

  11. Analysis of potential influence factors on background urinary benzene concentration among a non-smoking, non-occupationally exposed general population sample.

    Science.gov (United States)

    Campagna, Marcello; Satta, Giannina; Campo, Laura; Flore, Valeria; Ibba, Antonio; Meloni, Michele; Tocco, Maria Giuseppina; Avataneo, Giuseppe; Flore, Costantino; Fustinoni, Silvia; Cocco, Pierluigi

    2014-01-01

    Analytical difficulties and lack of a biological exposure index and reference values have prevented using unmetabolized urinary benzene (UB) excretion as a biomarker of low-level environmental exposure. To explore what environmental factors beyond active smoking may contribute to environmental exposure to benzene, we monitored UB excretion in a non-smoking, non-occupationally exposed sample of the general population. Two spot urine samples were obtained from 86 non-smoking, non-occupationally exposed subjects, selected among a random sample of the general population of the metropolitan area of Cagliari (Sardinia, Italy), at 8:00 a.m. (UBm) and 8:00 p.m. (UBe). UB was measured by headspace solid-phase microextraction (HS-SPME) followed by gas chromatography-mass spectrometry analysis. Questionnaire information on personal and environmental exposures during the sampling day was gathered with personal interviews. Multivariate analysis of variance and multiple regression model were applied to investigate the role of such variables on the level of UB. The ninety-fifth percentile of UBe in this population was 311.5 ng/L, which is tentatively proposed as the UB guidance value for unexposed populations. UBm and urban residence were the only predictors of a significant increase in UBe excretion. Self-reported residential vehicular traffic will not account for the excess median value among urban residents; commuting time among urban residents showed a suggestive nonsignificant linear correlation with UBe, but the small sample size prevented reliable inference to be drawn. Age, environmental tobacco smoking, employment status and body mass index did not affect UB excretion. Our findings support the use of unmetabolized UB as a specific and sensitive biomarker of low-level environmental exposure to benzene.

  12. Hinkley Point 'C' power station public inquiry: proof of evidence on potential off-site effects of radiation

    International Nuclear Information System (INIS)

    Western, D.J.

    1988-09-01

    A public inquiry has been set up to examine the planning application made by the Central Electricity Generating Board (CEGB) for the construction of a 1200 MW Pressurized Water Reactor power station at Hinkley Point (Hinkley Point ''C'') in the United Kingdom. This evidence to the Inquiry is concerned with the potential of the proposed Hinkely Point ''C'' PWR to increase the exposure of members of the public offsite to radiation. The policy is to replicate the design of the Sizewell ''B'' reactor. The evidence examined in great detail at the Sizewell ''B'' Public Inquiry where the Inspector concluded that the risk would be very small. The purpose of this evidence is to provide an explicit account of the potential off-site effects of radiation at the Hinkley Point site, so that it can be seen that there is nothing specific to this location that could lead to a different conclusion. (author)

  13. Public-Private Partnership Potential in Property Management of Russia and Belarus Union State

    Directory of Open Access Journals (Sweden)

    A P Vihrjan

    2010-09-01

    Full Text Available The article describes a possibility of implementation of an institute of public-private partnership, mainly concessions, as a notable component of management system of the Union State's of Russia and Belarus Property.

  14. Increasing medical students' engagement in public health: case studies illustrating the potential role of online learning.

    Science.gov (United States)

    Sheringham, J; Lyon, A; Jones, A; Strobl, J; Barratt, H

    2016-09-01

    The value of e-learning in medical education is widely recognized but there is little evidence of its value in teaching medical students about public health. Such evidence is needed because medical students' engagement with public health has been low. We present three recent case studies from UK medical schools to illustrate diverse ways in which online approaches can increase medical students' engagement with learning public health. A comparative case study approach was used applying quantitative and qualitative data to examine engagement in terms of uptake/use amongst eligible students, acceptability and perceived effectiveness using an analytic framework based on Seven Principles of Effective Teaching. Across the three case studies, most (67-85%) eligible students accessed online materials, and rated them more favourably than live lectures. Students particularly valued opportunities to use e-learning flexibly in terms of time and place. Online technologies offered new ways to consolidate learning of key public health concepts. Although students found contributing to online discussions challenging, it provided opportunities for students to explore concepts in depth and enabled students that were uncomfortable speaking in face-to-face discussions to participate. E-learning can be applied in diverse ways that increase medical student engagement with public health teaching. © The Author 2015. Published by Oxford University Press on behalf of Faculty of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  15. Chemical mixtures in untreated water from public-supply wells in the U.S.--occurrence, composition, and potential toxicity.

    Science.gov (United States)

    Toccalino, Patricia L; Norman, Julia E; Scott, Jonathon C

    2012-08-01

    Chemical mixtures are prevalent in groundwater used for public water supply, but little is known about their potential health effects. As part of a large-scale ambient groundwater study, we evaluated chemical mixtures across multiple chemical classes, and included more chemical contaminants than in previous studies of mixtures in public-supply wells. We (1) assessed the occurrence of chemical mixtures in untreated source-water samples from public-supply wells, (2) determined the composition of the most frequently occurring mixtures, and (3) characterized the potential toxicity of mixtures using a new screening approach. The U.S. Geological Survey collected one untreated water sample from each of 383 public wells distributed across 35 states, and analyzed the samples for as many as 91 chemical contaminants. Concentrations of mixture components were compared to individual human-health benchmarks; the potential toxicity of mixtures was characterized by addition of benchmark-normalized component concentrations. Most samples (84%) contained mixtures of two or more contaminants, each at concentrations greater than one-tenth of individual benchmarks. The chemical mixtures that most frequently occurred and had the greatest potential toxicity primarily were composed of trace elements (including arsenic, strontium, or uranium), radon, or nitrate. Herbicides, disinfection by-products, and solvents were the most common organic contaminants in mixtures. The sum of benchmark-normalized concentrations was greater than 1 for 58% of samples, suggesting that there could be potential for mixtures toxicity in more than half of the public-well samples. Our findings can be used to help set priorities for groundwater monitoring and suggest future research directions for drinking-water treatment studies and for toxicity assessments of chemical mixtures in water resources. Published by Elsevier B.V.

  16. Chemical mixtures in untreated water from public-supply wells in the U.S. - Occurrence, composition, and potential toxicity

    Energy Technology Data Exchange (ETDEWEB)

    Toccalino, Patricia L., E-mail: ptocca@usgs.gov [U.S. Geological Survey (USGS), 6000 J Street, Placer Hall, Sacramento, California 95819 (United States); Norman, Julia E., E-mail: jnorman@usgs.gov [USGS, 2130 SW 5th Avenue, Portland, Oregon 97201 (United States); Scott, Jonathon C., E-mail: jon@usgs.gov [USGS, 202 NW 66th Street, Oklahoma City, Oklahoma 73116 (United States)

    2012-08-01

    Chemical mixtures are prevalent in groundwater used for public water supply, but little is known about their potential health effects. As part of a large-scale ambient groundwater study, we evaluated chemical mixtures across multiple chemical classes, and included more chemical contaminants than in previous studies of mixtures in public-supply wells. We (1) assessed the occurrence of chemical mixtures in untreated source-water samples from public-supply wells, (2) determined the composition of the most frequently occurring mixtures, and (3) characterized the potential toxicity of mixtures using a new screening approach. The U.S. Geological Survey collected one untreated water sample from each of 383 public wells distributed across 35 states, and analyzed the samples for as many as 91 chemical contaminants. Concentrations of mixture components were compared to individual human-health benchmarks; the potential toxicity of mixtures was characterized by addition of benchmark-normalized component concentrations. Most samples (84%) contained mixtures of two or more contaminants, each at concentrations greater than one-tenth of individual benchmarks. The chemical mixtures that most frequently occurred and had the greatest potential toxicity primarily were composed of trace elements (including arsenic, strontium, or uranium), radon, or nitrate. Herbicides, disinfection by-products, and solvents were the most common organic contaminants in mixtures. The sum of benchmark-normalized concentrations was greater than 1 for 58% of samples, suggesting that there could be potential for mixtures toxicity in more than half of the public-well samples. Our findings can be used to help set priorities for groundwater monitoring and suggest future research directions for drinking-water treatment studies and for toxicity assessments of chemical mixtures in water resources. - Highlights: Black-Right-Pointing-Pointer We assessed mixtures in untreated groundwater samples from public

  17. Iodine Nutritional Status in Schoolchildren from Public Schools in Brazil: A Cross-Sectional Study Exposes Association with Socioeconomic Factors and Food Insecurity.

    Science.gov (United States)

    Campos, Renata de Oliveira; Reboucas, Sara Cristina Lima; Beck, Rebeca; de Jesus, Lorena Rejane Maia; Ramos, Yanne Rocha; Barreto, Iasmin Dos Santos; Marques, Tamires Xavier; Cerqueira, Taise Lima Oliveira; Santos, William Alves; Oliveira, Clotilde Assis; Teixeira, Leonardo Sena Gomes; Souza, Vanessa Cristina de Oliveira; Barbosa, Fernando; Ramos, Helton Estrela

    2016-07-01

    National programs of salt iodization were implemented in Brazil to combat iodine deficiency (ID) in children of school age. Currently, there are limited data in Brazil on those still vulnerable to this deficiency and the state of nutritional iodine status in the northeast region of Brazil, where children are vulnerable to malnutrition. The aim of this study was to analyze the iodine nutritional status, household food insecurity, socioeconomic and demographic characteristics among schoolchildren from the public school system living in state the state of Bahia, Brazil. A cross-sectional study was conducted on 1419 schoolchildren in Bahia between the ages of 6 and 14 years old. Anthropometric parameters, urinary iodine concentrations (UIC), and thyrotropin (TSH) measurements were evaluated from blood spots on filter paper. The mean UIC was 206.4 ± 80.5 μg/L, with a median of 221.6 μg/L, indicating sufficient iodine intake in the region. Low urinary iodide concentration (300 μg/L, indicating the coexistence of excessive iodine intake (EII). The mean TSH was 1.0 ± 0.6 mIU/L. The body mass index category "overweight/obesity" was a protective factor against EII (odds ratio [OR] = 0.64 [confidence interval (CI) 0.4-1.0]; p = 0.07). Urban areas (73%) had a mean UIC of 213.1 ± 80 μg/L compared with 176.8 ± 76.1 μg/L in rural areas. The risk for EII increased in children living in a house with more than six people (OR = 1.62 [CI 0.9-2.6]; p  0.05). A significant proportion of schoolchildren still have ID or EII in the northeast region of Brazil, emphasizing the importance of committed public policies to address this problem. Socioeconomic factors and the lack of education about nutritional importance of iodine were important influencing factors in the presence of ID in schoolchildren.

  18. Exposing the faults

    International Nuclear Information System (INIS)

    Richardson, P.J.

    1989-01-01

    UK NIREX, the body with responsibility for finding an acceptable strategy for deposition of radioactive waste has given the impression throughout its recent public consultation that the problem of nuclear waste is one of public and political acceptability, rather than one of a technical nature. However the results of the consultation process show that it has no mandate from the British public to develop a single, national, deep repository for the burial of radioactive waste. There is considerable opposition to this method of managing radioactive waste and suspicion of the claims by NIREX concerning the supposed integrity and safety of this deep burial option. This report gives substance to those suspicions and details the significant areas of uncertainty in the concept of effective geological containment of hazardous radioactive elements, which remain dangerous for tens of thousands of years. Because the science of geology is essentially retrospective rather than predictive, NIREX's plans for a single, national, deep 'repository' depend heavily upon a wide range of assumptions about the geological and hydrogeological regimes in certain areas of the UK. This report demonstrates that these assumptions are based on a limited understanding of UK geology and on unvalidated and simplistic theoretical models of geological processes, the performance of which can never be directly tested over the long time-scales involved. NIREX's proposals offer no guarantees for the safe and effective containment of radioactivity. They are deeply flawed. This report exposes the faults. (author)

  19. Only when the societal impact potential is high? A panel study of the relationship between public service motivation and performance

    DEFF Research Database (Denmark)

    Loon, Nina van; Kjeldsen, Anne Mette; Andersen, Lotte Bøgh

    Does the performance of public organizations benefit from high public service motivation (PSM) under all circumstances? This article studies whether the societal impact potential (SIP) – the degree to which the job provides opportunities to contribute to society of the job –moderates the relation......Does the performance of public organizations benefit from high public service motivation (PSM) under all circumstances? This article studies whether the societal impact potential (SIP) – the degree to which the job provides opportunities to contribute to society of the job –moderates...... the relationship between PSM and self-perceived performance, first on the individual level, and second on an organizational level. By shifting to the organizational level we are able to provide a test over time. Using organizational panel data from 2010 and 2012 on approximately 13.000 public employees, we...... (organizational level) or even no relationship (individual level) when SIP is low. This is an important insight for organizations that aim to enhance their performance through PSM as it shows that individual motives only contribute to performance when they are accounted for in the design of the work....

  20. Microarray detection and qPCR screening of potential biomarkers of Folsomia candida (Collembola: Isotomidae) exposed to Bt proteins (Cry1Ab and Cry1Ac)

    DEFF Research Database (Denmark)

    Yuan, Yiyang; Krogh, Paul Henning; Bai, Xue

    2014-01-01

    The impact of Bt proteins on non-target arthropods is less understood than their effects on target organisms where the mechanism of toxic action is known. Here, we report the effects of two Bt proteins, Cry1Ab and Cry1Ac, on gene expression in the non-target collembolan, Folsomia candida....... A customized microarray was used to study gene expression in F. candida specimens that were exposed to Cry1Ab and Cry1Ac. All selected transcripts were subsequently confirmed by qPCR. Eleven transcripts were finally verified, and three of them were annotated. The responses of all eleven transcripts were...... tested in specimens for both Cry1Ab and Cry1Ac at a series of concentrations. These transcripts were separated into two and three groups for Cry1Ab and Cry1Ac, respectively, depend on their expression levels. However, those eleven transcripts did not respond to the Bt proteins in Bt-rice residues....

  1. Increasing both the public health potential of basic research and the scientist satisfaction. An international survey of bio-scientists.

    Science.gov (United States)

    Sorrentino, Carmen; Boggio, Andrea; Confalonieri, Stefano; Hemenway, David; Scita, Giorgio; Ballabeni, Andrea

    2016-01-01

    Basic scientific research generates knowledge that has intrinsic value which is independent of future applications. Basic research may also lead to practical benefits, such as a new drug or diagnostic method. Building on our previous study of basic biomedical and biological researchers at Harvard, we present findings from a new survey of similar scientists from three countries. The goal of this study was to design policies to enhance both the public health potential and the work satisfaction and test scientists' attitudes towards these factors. The present survey asked about the scientists' motivations, goals and perspectives along with their attitudes concerning  policies designed to increase both the practical (i.e. public health) benefits of basic research as well as their own personal satisfaction. Close to 900 basic investigators responded to the survey; results corroborate the main findings from the previous survey of Harvard scientists. In addition, we find that most bioscientists disfavor present policies that require a discussion of the public health potential of their proposals in grants but generally favor softer policies aimed at increasing the quality of work and the potential practical benefits of basic research. In particular, bioscientists are generally supportive of those policies entailing the organization of more meetings between scientists and the general public, the organization of more academic discussion about the role of scientists in the society, and the implementation of a "basic bibliography" for each new approved drug.

  2. DEFINITION OF PUBLIC SERVICE OBLIGATION POTENTIAL IN THE NEW EU MEMBER STATES

    Directory of Open Access Journals (Sweden)

    Martin HROMÁDKA

    2017-04-01

    Full Text Available This paper deals with public service obligation, a form of state aid that applies to air services. The paper first provides general information on the European legislation applying to this form of state aid, and elaborates the legal framework and general principles. The second part is dedicated to a comparison of a similar subsidizing programme in the USA and Australia. An examination of current imposed public service obligation routes in Europe is provided in the following section. The coefficients defining the number of imposed PSO routes per various geo-economic variables have been defined.

  3. The role of governments in promoting a realistic public understanding of the potentialities of nuclear power

    International Nuclear Information System (INIS)

    Shapar, H.K.

    1983-01-01

    Adverse public attitudes towards nuclear power have been and continue to be a significant obstacle in the way of nuclear power growth. The three main ways in which governments could help to promote public understanding of nuclear power are 1) by carrying out effectively their traditional tasks of deciding priorities, funding research, encouraging information exchange with other countries and regulating nuclear activities; 2) by providing basic information about the need for nuclear power and its economic importance and providing appropriate opportunities for changes in policies and 3) by showing leadership particularly when no clear course is apparent. (U.K.)

  4. The potential danger of negative free publicity for the consumer-brand relationship

    NARCIS (Netherlands)

    Tolboom, M.; Bronner, F.; Smit, E.

    2012-01-01

    How can free publicity contribute to building high quality consumer-brand relationships or strong brands? This is an important question because building strong brands is the main objective of brand management. Consumers are more willing to receive communication messages from strong brands (Smit et

  5. Perspectives on Open Access Opportunities for IS Research Publication: Potential Benefits for Researchers, Educators, and Students

    Science.gov (United States)

    Woszczynski, Amy B.; Whitman, Michael E.

    2016-01-01

    Access to current research materials, pedagogical best practices, and relevant knowledge has become problematic as journal subscription costs have increased. Increasing delays in the traditional publication timeline, coupled with high subscription costs, have resulted in a diminished ability for IS faculty and their students to access the most…

  6. Understanding the current status and exploring the potential for distance education in public health in India.

    Science.gov (United States)

    Sharma, Kavya; George, Sunil; Zodpey, Sanjay

    2011-01-01

    Continuing education of health care providers plays an important role in producing a health work force that is efficient and effective. In India public health education has primarily relied on conventional methods of training. However, such methods have limitations in equipping the health workforce of a vast and varied country like India. This paper analyzes the current status of distance education in public health and lists the various courses that are presently available in India through the distance education mode. Presently 25 institutions in India are offering 69 courses in various domains of public health through distance education. The providers of these programs comprised both government and private educational institutions. This paper also points out the role and importance of various stakeholders in the design and delivery of distance education programs in public health and raises key areas that need attention in the governance of such programs. It urges the use of digital technology in the delivery of distance education programs and points out how distance education that is designed and delivered using the latest technology could address the current gap in training human resources for health in India.

  7. Photosynthesis and oxidative stress in the restinga plant species Eugenia uniflora L. exposed to simulated acid rain and iron ore dust deposition: Potential use in environmental risk assessment

    Energy Technology Data Exchange (ETDEWEB)

    Rust Neves, Natalia; Oliva, Marco Antonio; Cruz Centeno, Danilo da; Costa, Alan Carlos; Ferreira Ribas, Rogerio [Departamento de Biologia Vegetal, Universidade Federal de Vicosa, Av. PH Rolfs, Campus, Vicosa, Minas Gerais, 36570-000 (Brazil); Gusmao Pereira, Eduardo, E-mail: egpereira@gmail.com [Departamento de Biologia Vegetal, Universidade Federal de Vicosa, Av. PH Rolfs, Campus, Vicosa, Minas Gerais, 36570-000 (Brazil)

    2009-06-01

    The Brazilian sandy coastal plain named restinga is frequently subjected to particulate and gaseous emissions from iron ore factories. These gases may come into contact with atmospheric moisture and produce acid rain. The effects of the acid rain on vegetation, combined with iron excess in the soil, can lead to the disappearance of sensitive species and decrease restinga biodiversity. The effects of iron ore dust deposition and simulated acid rain on photosynthesis and on antioxidant enzymes were investigated in Eugenia uniflora, a representative shrub species of the restinga. This study aimed to determine the possible utility of this species in environmental risk assessment. After the application of iron ore dust as iron solid particulate matter (SPM{sub Fe}) and simulated acid rain (pH 3.1), the 18-month old plants displayed brown spots and necrosis, typical symptoms of iron toxicity and injuries caused by acid rain, respectively. The acidity of the rain intensified leaf iron accumulation, which reached phytotoxic levels, mainly in plants exposed to iron ore dust. These plants showed the lowest values for net photosynthesis, stomatal conductance, transpiration, chlorophyll a content and electron transport rate through photosystem II (PSII). Catalase and superoxide dismutase activities were decreased by simulated acid rain. Peroxidase activity and membrane injury increased following exposure to acid rain and simultaneous SPM{sub Fe} application. Eugenia uniflora exhibited impaired photosynthetic and antioxidative metabolism in response to combined iron and acid rain stresses. This species could become a valuable tool in environmental risk assessment in restinga areas near iron ore pelletizing factories. Non-invasive evaluations of visual injuries, photosynthesis and chlorophyll a fluorescence, as well as invasive biochemical analysis could be used as markers.

  8. Strategies for exposing students to potential careers in the geosciences and preparing them with skillsets valued by today's workforce: a case study

    Science.gov (United States)

    Sloan, V.; Haacker, R.

    2016-12-01

    Students, graduate students, and postdocs facing the job market cite a lack of familiarity with non-academic careers in the geosciences, uncertainty about the skills needed, and fear of the future. We work with these groups in several education programs at the National Center for Atmospheric Research (NCAR), and have interviewed and polled them about these issues. Surveys of and focus groups with alumni from two of these programs, an undergraduate career development program and a postdoctoral study program, provided insight into their employment and the skills that they see as valuable in their careers. Using this data, we redesigned the one-week undergraduate program, called the NCAR Undergraduate Leadership Workshop, with the goals of: (1) exposing students to the diversity of careers in the geosciences; (2) providing students with practice developing their non-technical skills, and; (3) creating content about careers in the atmospheric sciences for sharing with other students in the community. Students self-organized into consulting groups and had to propose and design their projects. During the course of the week, students interacted with approximately twenty professionals from fields in or related to the geosciences through lectures, lunch conversations, and student-led interviews. The professionals were asked to described their own work and the meanders of their career paths, to illustrate the range of professions in our field. The teams then developed creative materials intended for sharing these profiles, such as websites, powerpoint presentations and videos, and presented them formally at the week's end. In this presentation, we will share about this case study, the survey results on competencies valued in today's STEM workforce, and techniques for giving students practice developing those skills.

  9. Photosynthesis and oxidative stress in the restinga plant species Eugenia uniflora L. exposed to simulated acid rain and iron ore dust deposition: Potential use in environmental risk assessment

    International Nuclear Information System (INIS)

    Rust Neves, Natalia; Oliva, Marco Antonio; Cruz Centeno, Danilo da; Costa, Alan Carlos; Ferreira Ribas, Rogerio; Gusmao Pereira, Eduardo

    2009-01-01

    The Brazilian sandy coastal plain named restinga is frequently subjected to particulate and gaseous emissions from iron ore factories. These gases may come into contact with atmospheric moisture and produce acid rain. The effects of the acid rain on vegetation, combined with iron excess in the soil, can lead to the disappearance of sensitive species and decrease restinga biodiversity. The effects of iron ore dust deposition and simulated acid rain on photosynthesis and on antioxidant enzymes were investigated in Eugenia uniflora, a representative shrub species of the restinga. This study aimed to determine the possible utility of this species in environmental risk assessment. After the application of iron ore dust as iron solid particulate matter (SPM Fe ) and simulated acid rain (pH 3.1), the 18-month old plants displayed brown spots and necrosis, typical symptoms of iron toxicity and injuries caused by acid rain, respectively. The acidity of the rain intensified leaf iron accumulation, which reached phytotoxic levels, mainly in plants exposed to iron ore dust. These plants showed the lowest values for net photosynthesis, stomatal conductance, transpiration, chlorophyll a content and electron transport rate through photosystem II (PSII). Catalase and superoxide dismutase activities were decreased by simulated acid rain. Peroxidase activity and membrane injury increased following exposure to acid rain and simultaneous SPM Fe application. Eugenia uniflora exhibited impaired photosynthetic and antioxidative metabolism in response to combined iron and acid rain stresses. This species could become a valuable tool in environmental risk assessment in restinga areas near iron ore pelletizing factories. Non-invasive evaluations of visual injuries, photosynthesis and chlorophyll a fluorescence, as well as invasive biochemical analysis could be used as markers.

  10. Knowledge, risk perception and mitigation measures towards Ebola virus disease by potentially exposed bushmeat handlers in north-central Nigeria: Any critical gap?

    Science.gov (United States)

    Alhaji, N B; Yatswako, S; Oddoh, E Y

    2018-02-01

    The bushmeat industry has been a topic of increasing importance among public health officials for its influence on zoonotic diseases transmission, such as Ebola virus disease (EVD), a rare and severe infectious disease of humans and non-human primates. This survey assessed knowledge/awareness, risk perceptions and mitigation practices towards EVD among bushmeat handlers in north-central Nigeria. These characteristics are premise to level of preparedness against appropriate risk prevention and control. A questionnaire-based cross-sectional study was conducted between January and December 2015 on 395 bushmeat handlers. Descriptive and analytical statistical analyses were performed using Epi-Info 3.5.3 software, and p knowledge than the hunters. Handlers with tertiary education were more likely (OR 3.22; 95% CI: 1.56-6.67) to possess significant satisfactory knowledge/awareness about EVD. Also, vendors were more likely (OR 1.85; 95% CI: 1.01-3.42) to practice satisfactory mitigation measures than the hunters. Only handlers with tertiary education were more likely (OR 2.48; 95% CI: 1.26-4.89) to significantly practice satisfactory mitigation measures against EVD. Although most of the handlers possessed significant knowledge/awareness about EVD, few applied mitigation measures against its infection, which is the challenging gap. There is a need for collaborations between the public health, veterinary and wildlife authorities in the provision of health information to bushmeat handlers on better management of emerging and re-emerging zoonotic viral diseases of wildlife origin. © 2017 Blackwell Verlag GmbH.

  11. Potential benefits of employee portals in public administrations: implementation and proactive behaviour towards the organization

    Directory of Open Access Journals (Sweden)

    Héctor Marcos Pérez-Feijoo

    2015-06-01

    Full Text Available The aim of this article is the determination of the advantages achieved through the implementation of an employee portal, both for the government and for the users of the portal. We proposed an adaptation of the Huang, Jin and Yang (2004 model, based on the organizational support theory (Eisenberger et al., 1986. This theory predicts a proactive behaviour of employees wheter they perceive a support of the organization. In this case, the trigger for that perception is the satisfaction derived by the benefits to personnel provided by an employee portal. Through an empirical study, conducted among public school teachers, we have found evidence of the perception of organizational support among public employees when the portal is deployes. However we haven´t found a link between that support and a proactive behaviour towards the organization.

  12. Estimation of the contribution of neutrons to the equivalent dose for personnel occupationally exposed and public in medical facilities: X-ray with energy equal or greater than 10MV

    International Nuclear Information System (INIS)

    Gonzalez, Alfonso Mayer; Jimenez, Roberto Ortega; Sanchez, Mario A. Reyes; Moranchel y Mejia, Mario

    2013-01-01

    In Mexico the use of electron accelerators for treating cancerous tumors had grown enormously in the last decade. When the treatments are carried out with X-ray beam energy below 10 MV the design of the shielding of the radioactive facility is determined by analyzing the interaction of X-rays, which have a direct impact and dispersion, with materials of the facility. However, when it makes use of X-ray beam energy equal to or greater than 10 MV the neutrons presence is imminent due to their generation by the interaction of the primary beam X-ray with materials head of the accelerator and of the table of treatment, mainly. In these cases, the design and calculation of shielding considers the generation of high-energy neutrons which contribute the equivalent dose that public and Occupationally Staff Exposed (POE) will receive in the areas surrounding the facility radioactive. However, very few measurements have been performed to determine the actual contribution to the neutron dose equivalent received by POE and public during working hours. This paper presents an estimate of the actual contribution of the neutron dose equivalent received by public and POE facilities in various radioactive medical use, considering many factors. To this end, measurements were made of the equivalent dose by using a neutron monitor in areas surrounding different radioactive installations (of Mexico) which used electron accelerators medical use during treatment with X-ray beam energy equal to or greater than 10 MV. The results are presented after a statistical analysis of a wide range of measures in order to estimate more reliability real contribution of the neutron dose equivalent for POE and the public. (author)

  13. The Potential to use Publication of Undergraduate Research as a Teaching Tool

    Science.gov (United States)

    Brevik, Eric C.; Lindbo, David L.; Belcher, Christopher

    2015-04-01

    Several studies crossing numerous disciplinary boundaries have demonstrated that undergraduate students benefit from research experiences. These benefits include personal and intellectual development, more and closer contact with faculty, the use of active learning techniques, the creation of high expectations, the development of creative and problem-solving skills, and the development of greater independence and intrinsic motivation to learn. The discipline also gains in that studies show undergraduates who engage in research experiences are more likely to remain science majors and finish their degree program. Research experiences come as close as possible to allowing undergraduates to experience what it is like to be an academic or research member of their profession working to advance their discipline, therefore enhancing their professional socialization into their chosen field. If the goals achieved by undergraduate research include introducing these students to the advancement of their chosen field, it stands to reason the ultimate ending to this experience would be the publication of a peer-reviewed paper. While not all undergraduate projects will end with a product worthy of peer-reviewed publication, some definitely do, and the personal experience of the authors indicates that undergraduate students who achieve publication get great satisfaction and a sense of personal achievement from that publication. While a top-tier international journal probably isn't going to be the ultimate destination for many of these projects, there are several appropriate outlets. The SSSA journal Soil Horizons has published several undergraduate projects in recent years, and good undergraduate projects can often be published in state academy of science journals. Journals focused expressly on publishing undergraduate research include the Journal of Undergraduate Research and Scholarly Excellence, Reinvention, and the American Journal of Undergraduate Research. Case studies of

  14. Public health implications from COGS and potential for risk stratification and screening.

    Science.gov (United States)

    Burton, Hilary; Chowdhury, Susmita; Dent, Tom; Hall, Alison; Pashayan, Nora; Pharoah, Paul

    2013-04-01

    The PHG Foundation led a multidisciplinary program, which used results from COGS research identifying genetic variants associated with breast, ovarian and prostate cancers to model risk-stratified prevention for breast and prostate cancers. Implementing such strategies would require attention to the use and storage of genetic information, the development of risk assessment tools, new protocols for consent and programs of professional education and public engagement.

  15. Touch and step potential analysis at 23.9kV to 4.16kV & 13.8kV to 4.16kV distribution substations with pad-mounted transformers, floating grounds, and other exposed ungrounded metal bodies using WinIGS

    Science.gov (United States)

    Guzman, David G.

    An electrical substation is composed of various subsystems that allow for the effective and safe operation of the power grid. One of the subsystems integrating a conventional substation is defined as the ground grid system. This system allows for the effective operation of the power grid and all the electrical equipment connected to it by providing a ground potential reference, commonly known as the system ground. In addition, the ground grid system provides safety to the workers and the public transiting inside or living nearby a substation by reducing the step and touch potential (or voltage) levels present during a system fault. In today's utility industry practices there is an increasing trend for using pad-mounted electrical equipment for substation applications in an effort to construct new or upgrade existing electrical facilities inside limited property spaces. This thesis work presents an analysis for the effects of touch and step voltages at existing distribution substations where 23.9kV to 4.16kV & 13.8kV to 4.16kV pad-mounted transformers and other pad-mounted switchgear was installed to replace the traditional station class equipment. Moreover, this study will expose modeling techniques employed to define and determine the effects of floating grounds and other exposed metal bodies inside or surrounding these substations using WinIGS; this is in an effort to determine any risks of electric shock associated with this type of installations. The results presented in this work are intended to verify the requirements for the ground grid analysis and design for 4.16kV distribution substations with pad-mounted equipment in order to prevent dangerous step and touch voltage levels appearing at these sites during system faults; and ultimately prevent exposing individuals to the risk of an electric shock.

  16. Perceived Accessibility of Public Transport as a Potential Indicator of Social Inclusion

    Directory of Open Access Journals (Sweden)

    Katrin Lättman

    2016-06-01

    Full Text Available Perceived accessibility has been acknowledged as an important aspect of transport policy since the 70s. Nevertheless, very few empirical studies have been conducted in this field. When aiming to improve social inclusion, by making sustainable transport modes accessible to all, it is important to understand the factors driving perceived accessibility. Unlike conventional accessibility measures, perceived accessibility focuses on the perceived possibilities and ease of engaging in preferred activities using different transport modes. We define perceived accessibility in terms of how easy it is to live a satisfactory life with the help of the transport system, which is not necessarily the same thing as the objective standard of the system. According to previous research, perceived accessibility varies with the subjectively-rated quality of the mode of transport. Thus, improvements in quality (e.g. trip planning, comfort, or safety increase the perceived accessibility and make life easier to live using the chosen mode of transport. This study (n=750 focuses on the perceived accessibility of public transport, captured using the Perceived Accessibility Scale PAC (Lättman, Olsson, & Friman, 2015. More specifically, this study aims to determine how level of quality affects the perceived accessibility in public transport. A Conditional Process Model shows that, in addition to quality, feeling safe and frequency of travel are important predictors of perceived accessibility. Furthermore, elderly and those in their thirties report a lower level of perceived accessibility to their day-to-day activities using public transport. The basic premise of this study is that subjective experiences may be as important as objective indicators when planning and designing for socially inclusive transport systems.

  17. Energy conservation potentials in the countries of Central and Eastern Europe - an expose of theses; Die Energiespeicherpotentiale in den Laendern Mittel- und Osteuropas - eine Darstellung der Thesen

    Energy Technology Data Exchange (ETDEWEB)

    Riesner, W. [Hochschule fuer Technik, Wirtschaft und Sozialwesen Zittau/Goerlitz FH, Zittau (Germany)

    1996-07-01

    The report compares western and eastern Europe in terms of their supply with fossil energy, the development of their primary and end-use energy consumption, and the development of their gross power generation. The technical state of energy conversion plants and electrothermal power plants, Russia`s energy conservation potential, and the efficacy of measures for enhancing electric energy efficiency in the Ukraine are described. Finally, a comparison of energy input coefficients and energy costs between the old and new federal states of Germany is made. (DG) [Deutsch] Bezueglich der Versorgung mit fossiler Energie, der Entwicklung des Primaer- und Endenergieverbrauchs und der Entwicklung der Brutto-Stromerzeugung werden West- und Osteuropa miteinander verglichen. Der technische Stand der Energieumwandlungsanlagen und der Elektrowaermeanlagen sowie das Energieeinsparungspotential in Russland und die Effektivitaet von Massnahmen zur Elektroenergieeffizienzsteigerung in der Ukraine werden dargestellt. Schliesslich erfolgt ein Vergleich der Energieintensitaets- und Energiekosten zwischen den alten und neuen Bundeslaendern der BRD. (DG)

  18. Determining potential adverse effects in marine fish exposed to pharmaceuticals and personal care products with the fish plasma model and whole-body tissue concentrations

    International Nuclear Information System (INIS)

    Meador, James P.; Yeh, Andrew; Gallagher, Evan P.

    2017-01-01

    The Fish Plasma Model (FPM) was applied to water exposure and tissue concentrations in fish collected from two wastewater treatment plant impacted estuarine sites. In this study we compared predicted fish plasma concentrations to Cmax values for humans, which represents the maximum plasma concentration for the minimum therapeutic dose. The results of this study show that predictions of plasma concentrations for a variety of pharmaceutical and personal care products (PPCPs) from effluent concentrations resulted in 37 compounds (54%) exceeding the response ratio (RR = Fish [Plasma]/1%Cmax total ) of 1 compared to 3 compounds (14%) detected with values generated with estuarine receiving water concentrations. When plasma concentrations were modeled from observed whole-body tissue residues, 16 compounds out of 24 detected for Chinook (67%) and 7 of 14 (50%) for sculpin resulted in an RR tissue value greater than 1, which highlights the importance of this dose metric over that using estuarine water. Because the tissue residue approach resulted in a high percentage of compounds with calculated response ratios exceeding a value of unity, we believe this is a more accurate representation for exposure in the field. Predicting plasma concentrations from tissue residues improves our ability to assess the potential for adverse effects in fish because exposure from all sources is captured. Tissue residues are also more likely to represent steady-state conditions compared to those from water exposure because of the inherent reduction in variability usually observed for field data and the time course for bioaccumulation. We also examined the RR in a toxic unit approach to highlight the importance of considering multiple compounds exhibiting a similar mechanism of action. - Highlights: • Fish Plasma Model (FPM) to assess risk based on water and fish tissue concentrations. • Plasma levels predicted with receiving water concentrations underestimate exposure for feral fish.

  19. Public officials exposed in the Matrix

    Index Scriptorium Estoniae

    2010-01-01

    Tundmatu arvutihäkker hüüdnimega Neo varastas Läti maksuametist andmeid avaliku sektori töötajate palkade kohta ning avaldas need suhtluskeskkonnas Twitter. See on Läti ühiskonnas tekitanud arutelu nii interneti turvalisuse kui palkade suuruse üle majanduskriisi tingimustes

  20. Buildings exposed to fire

    International Nuclear Information System (INIS)

    1987-01-01

    The 24 lectures presented to the colloquium cover the following subject fields: (1) Behaviour of structural components exposed to fire; (2) Behaviour of building materials exposed to fire; (3) Thermal processes; (4) Safety related, theoretical studies. (PW) [de

  1. Effects of β-arabinofuranosyladenine on potentially lethal damage induced in plateau phase mammalian cells exposed to U.V.-light

    International Nuclear Information System (INIS)

    Iliakis, G.

    1983-01-01

    The effect of β-arabinofuranosyladenine (β-araA), a specific inhibitor of DNA polymerases α and β, on the survival of plateau phase Ehrlich ascites tumour cells after U.V.-exposure has been studied. β-araA inhibited repair of U.V.-induced potentially lethal damage (PLD), when given to the cells after irradiation. An exponential survival curve (D 0 = 1 J/m 2 ) was obtained when irradiated cells were treated with β-araA at 120 μM. β-araA mainly affected the shoulder width of the survival curve but also changed the slope of the resistant 'tail' of the survival curve. The effect was irreversible at 80 μM and partly reversible at 20 μM. When β-araA was added to cultures in fresh or conditioned medium at 80 μM at various times after irradiation, there was a gradual decrease in PLD. Survival reached levels corresponding to those of untreated cells plated immediately after irradiation. If cells were incubated for additional times in fresh medium, survival increased to levels corresponding to those obtained with plateau phase cells after delayed plating, but did not occur in cells incubated in conditioned medium. The repair time constant for PLD was about 3 hours for cells incubated in fresh medium and about 6 hours incubated in conditioned medium. (author)

  2. The Potentials of New Public Sphere For Emerging Global Civil Society

    Directory of Open Access Journals (Sweden)

    Abul Sattar Khan

    2011-12-01

    Full Text Available New public sphere is characterized by the digital gadgets, global village, international citizenship and new global society. However, the common thread cutting through all these new concepts is the virtual soul of ‘connectivity’ that is riding on the ‘networking-tools’ which have now grown into an unprecedented giant ‘network-of-networks’ or simply put the ‘Internet’ with ‘social-networking’ and ‘social-software’ as the latest communication tools. International citizens travel on the information superhighways 24/7 and the communications across the planet never stops. It is however argued that NPS offers both challenges and prospects for the users depending on the availability of digital gadgets and digital literacy of the global citizens. This paper explores the pluses and minuses of this emerging environment for the members of global civil society by postulating a grounded model of the issue.

  3. Unsuccessfully Treated Hypertension: A Major Public Health Problem With a Potential Solution.

    Science.gov (United States)

    Furberg, Curt D; Sealey, Jean E; Blumenfeld, Jon D

    2017-09-01

    About one-half of all hypertensive adults do not have their blood pressure controlled. They are often prescribed medications that conform to national guidelines but they continue to have elevated blood pressure. This public health problem might be improved by applying plasma renin guided therapy. A contributor to the public health problem of unsuccessfully treated hypertension is that the circulating renin-angiotensin system (RAS) is not recognized in treatment guidelines as clinically relevant for the treatment of hypertension or as important as the body salt status for determining blood pressure levels. Another contributor to the problem is the lack of specificity in the package inserts for antihypertensive drugs. They do not specifically state under the heading "Indications" that RAS blockers are primarily most effective in hypertensive subjects with medium and high plasma renin levels; by contrast, natriuretic drugs are most effective in those with low plasma renin levels. Literature review. To address the problem of unsuccessfully treated hypertension, we recommend that the "Indications" section of package inserts for antihypertensive drugs be more specific. The primary indication for RAS blockers ought to be hypertension with medium and high plasma renin levels, and natriuretic agents for those with low plasma renin levels. Similar language ought to be added to treatment guidelines. Additionally, 3 other reasons for lack of blood pressure control also need to be addressed-failure to prescribe antihypertensive drugs to hypertensive subjects, failure of patients to fill prescriptions, and low drug adherence. © American Journal of Hypertension, Ltd 2017. All rights reserved. For Permissions, please email: journals.permissions@oup.com

  4. Assessment of the potential public health impact of Herpes Zoster vaccination in Germany.

    Science.gov (United States)

    Curran, Desmond; Van Oorschot, Desirée; Varghese, Lijoy; Oostvogels, Lidia; Mrkvan, Tomas; Colindres, Romulo; von Krempelhuber, Alfred; Anastassopoulou, Anastassia

    2017-10-03

    The aim of this study was to compare the public health impact of introducing 2 Herpes Zoster (HZ) vaccines, Zoster Vaccine Live (ZVL) versus a non-live adjuvanted subunit candidate vaccine (HZ/su), in the German population aged 50+ years split into 3 age cohorts, i.e. 50-59, 60-69 and 70+ years, respectively. A multi-cohort static Markov model was developed following age cohorts over their lifetime. Demographic data were obtained from the German federal statistical office. HZ incidence and the proportion of HZ individuals developing post-herpetic neuralgia (PHN) were derived from German specific sources. Age-specific vaccine efficacy and waning rates were based on published clinical trial data. Vaccine coverage for both vaccines was assumed to be 40%, with compliance of the second dose of the HZ/su vaccine of 70%. Sensitivity analyses were performed to assess the robustness of the results. It was estimated that, over the remaining lifetime since vaccination, the HZ/su vaccine would reduce the number of HZ cases by 725,233, 533,162 and 486,794 in the 3 age cohorts, respectively, compared with 198,477, 196,000 and 104,640, using ZVL. The number needed to vaccinate (NNV) to prevent one HZ case ranged from 8 to 11 using the HZ/su vaccine compared with 20 to 50 using ZVL. Corresponding NNV to prevent one PHN case ranged from 39 to 53 using the HZ/su vaccine compared with 94 to 198 using ZVL. Due to the higher, sustained vaccine efficacy, the candidate HZ/su vaccine demonstrated superior public health impact compared with ZVL.

  5. National survey of potential scenarios for occupational and public exposure to naturally occurring radioactive materials in the Republic of Cuba

    International Nuclear Information System (INIS)

    Fernandez Gomez, Isis Maria

    2012-01-01

    The naturally occurring radioactive materials (NORMs) unchanged in its natural state has been considered that can pose a problem from the radiological point of view; however, that are monitored by regulators has been rare. Furthermore, exposures to NORMs that have been altered during the exploitation of natural resources can in principle be regulated. The NORMs have found in some waste generated in various industries, e.g. metal scrap, sludge, slag and fluids. These materials, by-products and the end products of processing, can increase the exposure of both workers and members of the public. Besides, can have a significant environmental damage. Two important situations of exploitation of natural resources which may be present NORMs relevant in relation to the potential effects of these materials on human health and the environment, are: (1) when NORMs concentrations have risen above their natural levels in a product, byproduct or waste, (2) when the release of NORMs to the biosphere may increase due to physicochemical changes or the method by which the wastes are managed. This problem is considered and in Cuba has done a survey of all those potential scenarios of occupational and public exposure to naturally occurring radioactive materials. Documents and ongoing work carried out by the European Union and the International Atomic Energy Agency, have been taken as reference, to identify potential scenarios for occupational and public exposure to naturally occurring radioactive materials in Cuba. The availability of information is taken into account, and the level of care that has received this problem within the community of nations. Recommendatory criteria are developed for countries that can serve as an excellent reference for a study of this type. This issue is still in development in other regions, its relevance and importance from the point of view of radiation safety. The handling, storage, transport and use of equipment or contaminated waste with NORMs

  6. Probabilistic risk assessment from potential exposures to the public applied for innovative nuclear installations

    International Nuclear Information System (INIS)

    Dvorzhak, Alla; Mora, Juan C.; Robles, Beatriz

    2016-01-01

    Potential exposures are those that may occur as a result of unanticipated operational performance or accidents. Potential exposure situations are probabilistic in nature because they depend on uncertain events such as equipment failure, operator errors or external initiators beyond the control of the operator. Consequently, there may exist a range of possible radiological impacts that need to be considered. In this paper a Level 3 Probabilistic Safety Assessment (PSA) for a hypothetical scenario relevant to Innovative Nuclear Energy Systems (INS) was conducted using computer code MACCS (MELCOR Accident Consequence Code Systems). The acceptability of an INS was analyzed taking into account the general requirement that relocation or evacuation measures must not be necessary beyond the site boundary. In addition, deterministic modeling of the accident consequences for the critical meteorological conditions was carried out using the JRODOS decision support system (Real-time On-line Decision Support system for off-site emergency management in Europe). The approach used for dose and risk assessment from potential exposure of accidental releases and their comparison with acceptance criteria are presented. The methodology described can be used as input to the licensing procedure and engineering design considerations to help satisfy relevant health and environmental impact criteria for fission or fusion nuclear installations. - Highlights: • PSA Level-3 based on WinMACCS code is carried out for accidental release. • Family curves of percentiles for radiation exposure doses are constructed. • Risk indicators for potential exposure are defined. • Using of risk acceptance curve criteria is proposed for decision making process.

  7. Determining potential adverse effects in marine fish exposed to pharmaceuticals and personal care products with the fish plasma model and whole-body tissue concentrations.

    Science.gov (United States)

    Meador, James P; Yeh, Andrew; Gallagher, Evan P

    2017-11-01

    The Fish Plasma Model (FPM) was applied to water exposure and tissue concentrations in fish collected from two wastewater treatment plant impacted estuarine sites. In this study we compared predicted fish plasma concentrations to Cmax values for humans, which represents the maximum plasma concentration for the minimum therapeutic dose. The results of this study show that predictions of plasma concentrations for a variety of pharmaceutical and personal care products (PPCPs) from effluent concentrations resulted in 37 compounds (54%) exceeding the response ratio (RR = Fish [Plasma]/1%Cmax total ) of 1 compared to 3 compounds (14%) detected with values generated with estuarine receiving water concentrations. When plasma concentrations were modeled from observed whole-body tissue residues, 16 compounds out of 24 detected for Chinook (67%) and 7 of 14 (50%) for sculpin resulted in an RR tissue value greater than 1, which highlights the importance of this dose metric over that using estuarine water. Because the tissue residue approach resulted in a high percentage of compounds with calculated response ratios exceeding a value of unity, we believe this is a more accurate representation for exposure in the field. Predicting plasma concentrations from tissue residues improves our ability to assess the potential for adverse effects in fish because exposure from all sources is captured. Tissue residues are also more likely to represent steady-state conditions compared to those from water exposure because of the inherent reduction in variability usually observed for field data and the time course for bioaccumulation. We also examined the RR in a toxic unit approach to highlight the importance of considering multiple compounds exhibiting a similar mechanism of action. Published by Elsevier Ltd.

  8. Potential savings from an evidence-based consumer-oriented public education campaign on prescription drugs.

    Science.gov (United States)

    Donohue, Julie M; Fischer, Michael A; Huskamp, Haiden A; Weissman, Joel S

    2008-10-01

    To estimate potential savings associated with the Consumer Reports Best Buy Drugs program, a national educational program that provides consumers with price and effectiveness information on prescription drugs. National data on 2006 prescription sales and retail prices paid for angiotensin-converting enzyme inhibitors (ACEIs), β-blockers, calcium channel blockers, and 3-hydroxy-3-methylglutaryl coenzyme A (HMG-coA) reductase inhibitors (statins). We converted national data on aggregate unit sales of drugs in the four classes to defined daily doses (DDD) and estimated a range of potential savings from generic and therapeutic substitution. We estimated that $2.76 billion, or 7.83 percent of sales, could be saved if use of the drugs recommended by the educational program was increased. The recommended drugs' prices were 15-65 percent lower per DDD than their therapeutic alternatives. The majority (57.4 percent) of potential savings would be achieved through therapeutic substitution. Substantial savings can be achieved through greater use of comparatively effective and lower cost drugs recommended by a national consumer education program. However, barriers to dissemination of consumer-oriented drug information must be addressed before savings can be realized. © Health Research and Educational Trust.

  9. Exploring the Potential Emotional and Behavioural Impact of Providing Personalised Genomic Risk Information to the Public: A Focus Group Study.

    Science.gov (United States)

    Smit, Amelia K; Keogh, Louise A; Newson, Ainsley J; Hersch, Jolyn; Butow, Phyllis; Cust, Anne E

    2015-01-01

    To explore the potential emotional and behavioural impact of providing information on personalised genomic risk to the public, using melanoma as an example, to aid research translation. We conducted four focus groups in which 34 participants were presented with a hypothetical scenario of an individual's lifetime genomic risk of melanoma (using the term 'genetic risk'). We asked about understanding of genetic risk, who would choose to receive this risk information, potential emotional and behavioural impacts, and other concerns or potential benefits. Data were analysed thematically. Participants thought this risk information could potentially motivate preventive behaviours such as sun protection and related it to screening for other diseases including breast cancer. Factors identified as influencing the decision to receive genetic risk information included education level, children, age and gender. Participants identified potential negative impacts on the recipient such as anxiety and worry, and proposed that this could be mitigated by providing additional explanatory and prevention information, and contact details of a health professional for further discussion. Participants' concerns included workplace and insurance discrimination. Participants recognised the potential for both positive and negative emotional and behavioural impacts related to receiving information on the personalised genomic risk of melanoma. © 2015 S. Karger AG, Basel.

  10. The need for health impact assessment in China: Potential benefits for public health and steps forward

    Energy Technology Data Exchange (ETDEWEB)

    Wu Liming, E-mail: lmwu@scdc.sh.c [Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336 (China); Center for Environment and Population Health, Griffith University, Nathan 4111 (Australia); Rutherford, Shannon; Chu, Cordia [Center for Environment and Population Health, Griffith University, Nathan 4111 (Australia)

    2011-07-15

    Health impact assessment (HIA) is a useful tool to predict and estimate the potential health impact associated with programs, projects, and policies by comprehensively identifying relevant health determinants and their consequences. China is undergoing massive and rapid socio-economic changes leading to environment and population health challenges such as a large increase in non-communicable diseases, the emergence and re-emergence of infectious diseases, new health risks associated with environmental pollutants and escalating health inequality. These health issues are affected by multiple determinants which can be influenced by planned policies, programs, and projects. This paper discusses the needs for health impact assessment in China in order to minimize the negative health consequences from projects, programs and policies associated with rapid social and economic development. It first describes the scope of China's current impact assessment system and points out its inadequacy in meeting the requirements of population health protection and promotion. It then analyses the potential use of HIA and why China needs to develop and apply HIA as a tool to identify potential health impacts of proposed programs, projects and policies so as to influence decision-making early in the planning process. Thus, the paper recommends the development of HIA as a useful tool in China to enhance decision-making for the protection and promotion of population health. For this to happen, the paper outlines steps necessary for the establishment and successful implementation of HIA in China: beginning with the establishment of a HIA framework, followed by workforce capacity building, methodology design, and intersectoral collaboration and stakeholder engagement.

  11. The need for health impact assessment in China: Potential benefits for public health and steps forward

    International Nuclear Information System (INIS)

    Wu Liming; Rutherford, Shannon; Chu, Cordia

    2011-01-01

    Health impact assessment (HIA) is a useful tool to predict and estimate the potential health impact associated with programs, projects, and policies by comprehensively identifying relevant health determinants and their consequences. China is undergoing massive and rapid socio-economic changes leading to environment and population health challenges such as a large increase in non-communicable diseases, the emergence and re-emergence of infectious diseases, new health risks associated with environmental pollutants and escalating health inequality. These health issues are affected by multiple determinants which can be influenced by planned policies, programs, and projects. This paper discusses the needs for health impact assessment in China in order to minimize the negative health consequences from projects, programs and policies associated with rapid social and economic development. It first describes the scope of China's current impact assessment system and points out its inadequacy in meeting the requirements of population health protection and promotion. It then analyses the potential use of HIA and why China needs to develop and apply HIA as a tool to identify potential health impacts of proposed programs, projects and policies so as to influence decision-making early in the planning process. Thus, the paper recommends the development of HIA as a useful tool in China to enhance decision-making for the protection and promotion of population health. For this to happen, the paper outlines steps necessary for the establishment and successful implementation of HIA in China: beginning with the establishment of a HIA framework, followed by workforce capacity building, methodology design, and intersectoral collaboration and stakeholder engagement.

  12. Identification of traditional foods with public health potential for complementary feeding in Western Kenya

    DEFF Research Database (Denmark)

    Kinyuru, John N,; Konyole, Silvenus O.; Kenji, Glaston M.

    2012-01-01

    The diversity of traditional foods in Kisumu West District of Western Kenya was assessed with an aim to identify the foods with a potential for complementary feeding. Leaves were the most consumed plant part amongst vegetables, while a few fruits were consumed together with their seeds. Amaranthus...... with nutritional and health benefits as perceived by the locals. Traditional food processing methods such as boiling, fermentation and sun drying were identified. Thus exploitation of the species possessing nutrient, health and processing benefits needs to be explored in complementary feeding....

  13. Prevalence of fecal shedding of Salmonella organisms among captive green iguanas and potential public health implications.

    Science.gov (United States)

    Burnham, B R; Atchley, D H; DeFusco, R P; Ferris, K E; Zicarelli, J C; Lee, J H; Angulo, F J

    1998-07-01

    To determine prevalence of fecal shedding of Salmonella organisms among captive green iguanas (Iguana iguana). Cohort study. 12 captive green iguanas. Iguanas were isolated in an environmental chamber, and fecal samples were collected weekly for 10 consecutive weeks. Samples were incubated aerobically in tetrathionate broth for 18 to 24 hours. Aliquots were then transferred to Hektoen and Salmonella-Shigella agar plates and incubated for an additional 18 to 24 hours. Isolated colonies were subcultured on nutrient agar slants, and Salmonella isolates were serogrouped and serotyped. All 12 iguanas were found to be shedding Salmonella organisms at least once during the study, and multiple serotypes were isolated from 7 of the 12. Salmonella organisms were isolated from 88 of 106 (83%) fecal samples; 21 samples contained multiple Salmonella serotypes. Overall, 11 Salmonella serotypes were identified. In 74 of 100 instances, when a particular Salmonella serotype was isolated from an individual iguana, the same serotype was also isolated from a subsequent fecal sample from that iguana. Results suggested that most iguanas have a stable mixture of Salmonella serotypes in their intestinal tracts and intermittently or continuously shed Salmonella organisms in their feces. Veterinarians should advise their clients on precautions for reducing the risk of acquiring these organisms from their pets. Public health officials trying to determine whether an iguana is the source of a specific Salmonella serotype that caused infection in human patients should submit at least 3 fecal samples collected from the iguana 1 week apart for bacterial culture.

  14. Antibiotic Use in Agriculture and Its Consequential Resistance in Environmental Sources: Potential Public Health Implications

    Directory of Open Access Journals (Sweden)

    Christy Manyi-Loh

    2018-03-01

    Full Text Available Due to the increased demand of animal protein in developing countries, intensive farming is instigated, which results in antibiotic residues in animal-derived products, and eventually, antibiotic resistance. Antibiotic resistance is of great public health concern because the antibiotic-resistant bacteria associated with the animals may be pathogenic to humans, easily transmitted to humans via food chains, and widely disseminated in the environment via animal wastes. These may cause complicated, untreatable, and prolonged infections in humans, leading to higher healthcare cost and sometimes death. In the said countries, antibiotic resistance is so complex and difficult, due to irrational use of antibiotics both in the clinical and agriculture settings, low socioeconomic status, poor sanitation and hygienic status, as well as that zoonotic bacterial pathogens are not regularly cultured, and their resistance to commonly used antibiotics are scarcely investigated (poor surveillance systems. The challenges that follow are of local, national, regional, and international dimensions, as there are no geographic boundaries to impede the spread of antibiotic resistance. In addition, the information assembled in this study through a thorough review of published findings, emphasized the presence of antibiotics in animal-derived products and the phenomenon of multidrug resistance in environmental samples. This therefore calls for strengthening of regulations that direct antibiotic manufacture, distribution, dispensing, and prescription, hence fostering antibiotic stewardship. Joint collaboration across the world with international bodies is needed to assist the developing countries to implement good surveillance of antibiotic use and antibiotic resistance.

  15. Antibiotic Use in Agriculture and Its Consequential Resistance in Environmental Sources: Potential Public Health Implications.

    Science.gov (United States)

    Manyi-Loh, Christy; Mamphweli, Sampson; Meyer, Edson; Okoh, Anthony

    2018-03-30

    Due to the increased demand of animal protein in developing countries, intensive farming is instigated, which results in antibiotic residues in animal-derived products, and eventually, antibiotic resistance. Antibiotic resistance is of great public health concern because the antibiotic-resistant bacteria associated with the animals may be pathogenic to humans, easily transmitted to humans via food chains, and widely disseminated in the environment via animal wastes. These may cause complicated, untreatable, and prolonged infections in humans, leading to higher healthcare cost and sometimes death. In the said countries, antibiotic resistance is so complex and difficult, due to irrational use of antibiotics both in the clinical and agriculture settings, low socioeconomic status, poor sanitation and hygienic status, as well as that zoonotic bacterial pathogens are not regularly cultured, and their resistance to commonly used antibiotics are scarcely investigated (poor surveillance systems). The challenges that follow are of local, national, regional, and international dimensions, as there are no geographic boundaries to impede the spread of antibiotic resistance. In addition, the information assembled in this study through a thorough review of published findings, emphasized the presence of antibiotics in animal-derived products and the phenomenon of multidrug resistance in environmental samples. This therefore calls for strengthening of regulations that direct antibiotic manufacture, distribution, dispensing, and prescription, hence fostering antibiotic stewardship. Joint collaboration across the world with international bodies is needed to assist the developing countries to implement good surveillance of antibiotic use and antibiotic resistance.

  16. Harnessing the potential - Atlantic Canada's oil and gas industry : Newfoundland Ocean Industries special releases or publications

    International Nuclear Information System (INIS)

    1998-07-01

    A comprehensive overview of Atlantic Canada's oil and gas industry is presented, demonstrating the importance of oil and gas resources and their related industries to Atlantic Canada. The objective of the report is to provide a basis for a strategy to optimize opportunities within the region from the oil and gas sector. The report reviews the current status of the industry, including the region's resource potential and the oil and gas developments currently underway. The evolution of the oil and gas industry is discussed in terms of value chain components. A broad assessment of the region's supply, labour force, infrastructure, training, and research and development capabilities is presented, followed by a description of the industry's potential, its regulatory framework and the barriers and constraints affecting industry development. Appendices contain a chronological history of major events in Atlantic Canada's oil and gas industry (Appendix A); and overview of the Atlantic Accord and the Canada-Nova Scotia Accord's equalization offset provisions (Appendix B); a value chain matrix, detailing some 60 categories of industry requirements and a capsule assessment of the region's ability to meet them (Appendix C); and a listing of research and development institutions in Atlantic Canada, including their areas of specialization (Appendix D)

  17. Global public goods and the global health agenda: problems, priorities and potential

    Directory of Open Access Journals (Sweden)

    MacKellar Landis

    2007-09-01

    Full Text Available Abstract The 'global public good' (GPG concept has gained increasing attention, in health as well as development circles. However, it has suffered in finding currency as a general tool for global resource mobilisation, and is at risk of being attached to almost anything promoting development. This overstretches and devalues the validity and usefulness of the concept. This paper first defines GPGs and describes the policy challenge that they pose. Second, it identifies two key areas, health R&D and communicable disease control, in which the GPG concept is clearly relevant and considers the extent to which it has been applied. We point out that that, while there have been many new initiatives, it is not clear that additional resources from non-traditional sources have been forthcoming. Yet achieving this is, in effect, the entire purpose of applying the GPG concept in global health. Moreover, the proliferation of disease-specific programs associated with GPG reasoning has tended to promote vertical interventions at the expense of more general health sector strengthening. Third, we examine two major global health policy initiatives, the Global Fund against AIDS, Tuberculosis and Malaria (GFATM and the bundling of long-standing international health goals in the form of Millennium Development Goals (MDG, asking how the GPG perspective has contributed to defining objectives and strategies. We conclude that both initiatives are best interpreted in the context of traditional development assistance and, one-world rhetoric aside, have little to do with the challenge posed by GPGs for health. The paper concludes by considering how the GPG concept can be more effectively used to promote global health.

  18. The potential of mobile phones for increasing public participation in local government in South Africa

    Directory of Open Access Journals (Sweden)

    Hannah Thinyane

    2015-12-01

    Full Text Available This paper presents a critical discussion on the current use of technology and participation in local government. It discusses the rise in popularity of mobile devices, and how they have been used in ICT for development. The paper describes the results of a baseline study undertaken in a city within Makana Municipality in the Eastern Cape of South Africa, to empirically investigate how residents are currently using mobile phones and participating with local government around the area of service delivery. The findings illustrate the current state of mobile phone usage and capabilities, and the potential for using the mobile platform to increase participation in local government in South Africa. The paper also can be used to inform and guide project stakeholders on how best to implement m-participation strategies.

  19. The Potential Impact of the Transatlantic Trade and Investment Partnership (TTIP) on public health.

    Science.gov (United States)

    De Vogli, Roberto; Renzetti, Noemi

    2016-01-01

    This article aims to examine the potential health effects of the Transatlantic Trade and Investment partnership (TTIP). Our review indicates that, although proponents of the TTIP claim that the treaty will produce benefits to health-enhancing determinants such as economic growth and employment, evidence shows that previous trade liberalization policies are associated with increasing economic inequities. By reducing Technical Barriers to Trade (TBT) and by promoting increased cooperation between US and EU governmental agencies in the pharmaceutical sector, the TTIP could result in improved research cooperation and reduced duplication of processes. However, the TTIP chapter on Intellectual Property (IP) and Trade-Related Aspects of Intellectual Property Rights (TRIPS) that expand and extend patent monopolies, and delay the availability of generic drugs, are likely to cause underutilization of needed medications among vulnerable populations. The TTIP's Investor to State Dispute Settlement (ISDS) arbitration system, a mechanism that allows transnational companies (TNCs) to sue governments when a policy or law reduces the value of their investment, is likely to generate a negative impact on regulations aimed at increasing access to healthcare, and reducing tobacco, alcohol consumption, and diet-related diseases. The Sanitary and Phytosanitary Standards (SPS) of the TTIP is expected to weaken regulations in the food and agricultural sectors especially in the EU, with potentially negative effects on food safety and foodborne diseases. Finally, the ISDS is likely to infringe the ability of governments to tackle environmental problems such as climate change deemed to be the most important global health threat of the century. Our review concludes by discussing policy implications and the effect of the TTIP on democracy, national sovereignty and the balance of power between large TNCs and governments. It also discusses the adoption of an evidence-based precautionary principle

  20. Leveraging social media in the stem cell sector: exploring Twitter's potential as a vehicle for public information campaigns.

    Science.gov (United States)

    McNutt, Kathleen; Zarzeczny, Amy

    2017-10-01

    Our aim in this project was to explore Twitter's potential as a vehicle for an online public information campaign (PIC) focused on providing evidence-based information about stem cell therapies and the market for unproven stem cell-based interventions. We designed an online, Twitter-based PIC using classic design principles and identified a set of target intermediaries (organizations with online influence) using a network governance approach. We tracked the PIC's dissemination over a 2-month period, and evaluated it using metrics from the #SMMStandards Conclave. Participation was limited but the PIC achieved some reach and engagement. Social media based online PICs appear to have potential but also face challenges. Future research is required to better understand how to most effectively maximize their strengths.

  1. The vicious cycle of Slovenian book use and the potential role of public libraries in solving it

    Directory of Open Access Journals (Sweden)

    Teja Zorko

    2007-01-01

    Full Text Available The use of books in Slovenia is marked with an insufficient bookstore network and with a well developed network of public libraries with a large number of loans that supplements a market of cheap paperback books, which is known in large language communities abroad. The resolution on National Program for Culture among the set goals for the improvement of use of books in Slovenia states also encouragement to develop bookstore network, equally divided across the entire Slovenian cultural area, with which the formation of bookstore corners in the framework of already existing public cultural institutions is proposed. From 2003, Ministry of Culture is supporting the good bookstores, but the endeavors haven’t reached the set goals yet. This contribution brings theoretical presumptions of principal thinking on the possibility of directing the libraries in the direction of marketing the books and the findings of a survey conducted among the directors of Slovenian general libraries. The findings show the predominant directors’ opinion on principal usefulness of potential sale of books in libraries, especially for the users. Almost a half of the managers of all Slovenian public libraries in principle support the introduction of book sale in their library if proper conditions would have been set. However, they do not expect any financial benefit from this service.

  2. Cryptosporidium spp. in pet birds: genetic diversity and potential public health significance.

    Science.gov (United States)

    Qi, Meng; Wang, Rongjun; Ning, Changshen; Li, Xiaoyu; Zhang, Longxian; Jian, Fuchun; Sun, Yanru; Xiao, Lihua

    2011-08-01

    To characterize the prevalence and assess the zoonotic transmission burden of Cryptosporidium species/genotypes in pet birds in Henan, China, 434 fecal samples were acquired from 14 families of birds in pet shops. The overall prevalence of Cryptopsoridium was 8.1% (35/434) by the Sheather's sugar flotation technique. The Cryptosporidium-positive samples were analyzed by DNA sequence analysis of the small subunit (SSU) rRNA gene. Three Cryptosporidium species and two genotypes were identified, including C. baileyi (18/35 or 51.4%) in five red-billed leiothrixes (Leiothrix lutea), four white Java sparrows (Padda oryzivora), four common mynas (Acridotheres tristis), two zebra finches (Taeniopygia guttata), a crested Lark (Galerida cristata), a Gouldian finch (Chloebia gouldiae), and a black-billed magpie (Pica pica); Cryptosporidium meleagridis (3/35 or 8.6%) in a Bohemian waxwing (Bombycilla garrulus), a Rufous turtle dove (Streptopelia orientalis), and a fan-tailed pigeon (Columba livia); Cryptosporidium galli (5/35 or 14.3%) in four Bohemian waxwings (Bombycilla garrulus) and a silver-eared Mesia (Leiothrix argentauris); Cryptosporidium avian genotype III (3/35 or 8.6%) in two cockatiels (Nymphicus hollandicus) and a red-billed blue magpie (Urocissa erythrorhyncha); and Cryptosporidium avian genotype V (6/35 or 17.1%) in six cockatiels (Nymphicus hollandicus). Among the pet birds, 12 species represented new hosts for Cryptosporidum infections. The presence of C. meleagridis raises questions on potential zoonotic transmission of cryptosporidiosis from pet birds to humans. Copyright © 2011 Elsevier Inc. All rights reserved.

  3. Environmental stress in the Gulf of Mexico and its potential impact on public health.

    Science.gov (United States)

    Singleton, B; Turner, J; Walter, L; Lathan, N; Thorpe, D; Ogbevoen, P; Daye, J; Alcorn, D; Wilson, S; Semien, J; Richard, T; Johnson, T; McCabe, K; Estrada, J J; Galvez, F; Velasco, C; Reiss, K

    2016-04-01

    The Deepwater Horizon (DWH) oil spill in the Gulf of Mexico was the largest maritime oil spill in history resulting in the accumulation of genotoxic substances in the air, soil, and water. This has potential far-reaching health impacts on cleanup field workers and on the populations living in the contaminated coastal areas. We have employed portable airborne particulate matter samplers (SKC Biosampler Impinger) and a genetically engineered bacterial reporter system (umu-ChromoTest from EBPI) to determine levels of genotoxicity of air samples collected from highly contaminated areas of coastal Louisiana including Grand Isle, Port Fourchon, and Elmer's Island in the spring, summer and fall of 2011, 2012, 2013 and 2014. Air samples collected from a non-contaminated area, Sea Rim State Park, Texas, served as a control for background airborne genotoxic particles. In comparison to controls, air samples from the contaminated areas demonstrated highly significant increases in genotoxicity with the highest values registered during the month of July in 2011, 2013, and 2014, in all three locations. This seasonal trend was disrupted in 2012, when the highest genotoxicity values were detected in October, which correlated with hurricane Isaac landfall in late August of 2012, about five weeks before a routine collection of fall air samples. Our data demonstrate: (i) high levels of air genotoxicity in the monitored areas over last four years post DWH oil spill; (ii) airborne particulate genotoxicity peaks in summers and correlates with high temperatures and high humidity; and (iii) this seasonal trend was disrupted by the hurricane Isaac landfall, which further supports the concept of a continuous negative impact of the oil spill in this region. Copyright © 2015 Elsevier Inc. All rights reserved.

  4. Environmental attributable fractions in remote Australia: the potential of a new approach for local public health action.

    Science.gov (United States)

    McMullen, Cheryl; Eastwood, Ashley; Ward, Jeanette

    2016-04-01

    To determine local values for environmental attributable fractions and explore their applicability and potential for public health advocacy. Using World Health Organization (WHO) values for environmental attributable fractions, responses from a practitioner survey (73% response rate) were considered by a smaller skills-based panel to determine consensus values for Kimberley environmental attributable fractions (KEAFs). Applied to de-identified data from 17 remote primary healthcare facilities over two years, numbers and proportions of reasons for attendance directly attributable to the environment were calculated for all ages and children aged 0-4 years, including those for Aboriginal patients. Of 150,357 reasons for attendance for patients of all ages, 31,775 (21.1%) were directly attributable to the environment. The proportion of these directly due to the environment was significantly higher for Aboriginal patients than others (23.1% v 14.6%; penvironmental factors, 20% of total primary healthcare demand could be prevented and, importantly, some 25% of presentations by Aboriginal children. KEAFs have potential to monitor impact of local environmental investments. © 2015 Public Health Association of Australia.

  5. Preservation potential of subtle glacial landforms based on detailed mapping of recently exposed proglacial areas: application of unmanned aerial vehicle (UAV) and structure-from-motion (SfM)

    Science.gov (United States)

    Ewertowski, Marek; Evans, David; Roberts, David; Tomczyk, Aleksandra; Ewertowski, Wojciech

    2016-04-01

    Ongoing glacier retreat results in the continuous exposure of proglacial areas. Such areas contain invaluable information about glacial process-form relationships manifest in specific landform assemblages. However, preservation potential of freshly exposed glacial landforms is very low, as proglacial terrains are one of the most dynamic parts of the landscape. Therefore, rapid mapping and geomorphological characterisation of such areas is important from a glaciological and geomorphological point of view for proper understanding and reconstruction of glacier-landform dynamics and chronology of glacial events. Annual patterns of recession and relatively small areas exposed every year, mean that the performing of regular aerial or satellite survey is expensive and therefore impractical. Recent advances in technology enables the development of low-cost alternatives for traditional aerial surveys. Small unmanned aerial vehicles (UAV) can be used to acquire high-resolution (several cm) low-altitude photographs. The UAV-based photographs can be subsequently processed through the structure-from-motion process to generate detailed orthophotomaps and digital elevation models. In this study we present case studies from the forelands of various glaciers on Iceland and Svalbard representing different types of proglacial landscapes: Fláajökull (annual push moraines); Hofellsjökul (bedrock bedforms and push moraines); Fjallsjökull (marginal drainage network); Rieperbreen (crevasse squeeze ridges and longitudinal debris stripes); Ayerbreen (transverse debris ridges); Foxfonna (longitudinal debris stripes);Hørbyebreen (geometric ridge network); Nordenskiöldbreen (fluted till surface); Ebbabreen (controlled moraine complex). UAV campaigns were conducted using a low-cost quadcopter platform. Resultant orthophotos and DEMs enabled mapping and assessment of recent glacial landscape development in different types of glacial landsystems. Results of our study indicate that

  6. Public-Private Partnership as the Core Form of the Implementation of Russia’s Transport and Transit Potential

    Directory of Open Access Journals (Sweden)

    Valery Anatolyevich Tsvetkov

    2017-03-01

    Full Text Available The article discusses the theory and practice of the implementation and development of transport and transit potential (TTP of Russia. This could be an effective way to replace the natural resource rent as the main source of income for the state and economic actors. For the modernization of national economic system the key importance are innovative technologies in the development of transport and transit potential through the organization of the production of goods and services with the highest added value in Russia. We proposed and substantiated the hypothesis about the necessity of creation of a Federal company responsible for the financing and implementation of Russia’s transport and transit potential development projects on the principles of public-private partnership (PPP. The authors have revealed the economic, institutional and organizational prerequisites for the establishment of such a public-private partnership company. We have provided the opinions of scientists and experts showing the urgent need to create in one form or another a single operator to transport goods on the territory of Russia and the Eurasian economic Union. To prove the hypothesis, we presented a description and analysis of the factors affecting the value of transit freight transport on Euro-Asian routes. We paid the special attention to identify the reasons of the increasing competitive advantage of Maritime transport in the world’s goods movement system. The authors based the main conclusion that, first of all, the created publicprivate partnership company should be large due to tough competition of developing transit freight by land routes with the global Maritime container services. Secondly, it needs a significant state participation since the management of the world’s cargo flows requires the effort of foreign policy and geo-economic nature. We emphasized that this business entity would become an active proponent and lobbyist of the most effective

  7. Conditions of the potential for commercialization of the patent: the implementation of a technology public offering system technology at CNEN

    International Nuclear Information System (INIS)

    Archila, Daniela Lima Cerqueira

    2015-01-01

    This dissertation identifies the main factors which represent the conditions for the potential commercialization of patents aiming at the implementation of a system for technology public offering at CNEN as a strategy for creating licensing opportunities to the industrial sector. The method applied refers to an exploratory case study of a patented technology selected from a sample of CNEN's patent portfolio in the biopharmaceutical sector. The case study comprehends a field research of interviews conducted with two specialists in technology and innovation management, one researcher from CNEN and a biopharmaceutical company. The results show that among the nineteen main factors - related to technology, market, business and Science and Technology Organization (STO) - the market dynamics, the potential applications of the technology and an abstract of its main benefits compared to existing technologies are the major relevant information for each technology to be included in the public offering system. Other results indicate that the evaluation of such factors may be conducted by competent professionals to bring less uncertainty and risk to the early-stage of the innovation process, as well as enhance the potential interest of a company in the technology. On the other hand, the latter requires innovation capabilities to move the technology forward – additional R&D, scale-up, manufacturing and marketing - whilst the STO needs a entrepreneurial culture that mitigates its obstacles, creates more positive solutions for its routines and processes and gives sustainability to its Technology Transfer Office (TTO) through valuing its personnel in the long term. Finally, emphasis on technological partnerships with companies can be a motivating feature for directing the STO's patent strategy to the creation of proprietary technological platforms that reflect problems experienced by the commercial environment, as well as the development of this strategic patent

  8. Information and Communication Technologies (ICT) as keys to the enhancement of public awareness about potential earth impacts

    Science.gov (United States)

    Usikov, Denis A.

    2013-09-01

    The 2007 Planetary Defense Conference recommends "to provide or enhance Internet sites to show how threats evolve and to illustrate possible action scenarios". Thereby, establishment of informational and communicational AsteroidAware web-site with the exact, authentic data about the past and the present of Earth's impact events will assist in achievement of positive results and progress in different directions on political, international, social and scientific levels. Expanded ICT's capabilities for popularization of planetary defense can help in resolving the problem of low public interest. The project's primary intent lies in popularizing the concept of planetary defenses and attracting attention to the potential dangers that threaten the Earth from outer space. The result of the efforts falling into the boundaries of this project would be an increased amount of social participation in the process of developing solutions for and increasing awareness of potential collisions between various astral bodies and the Earth. The project is also aimed at creating a foundation for the interaction between scientists and executives from around the world to facilitate international efforts of searching for fitting measures towards lowering threat levels and developing strategies revolving around united actions against potential threats.

  9. Synthesis of public-private partnerships : potential issues and best practices for program and project implementation and administration.

    Science.gov (United States)

    2015-08-01

    Public-private partnerships (P3s or PPPs) offer an innovative procurement method for the public sector. : P3s involve collaborations between the public and private sectors to finance, develop or maintain transportation : infrastructure. In an era of ...

  10. Adolescents exposed to physical violence in the community: a survey in Brazilian public schools Encuesta en escuelas públicas de Brasil sobre la exposición de los adolescentes a la violencia en la comunidad

    Directory of Open Access Journals (Sweden)

    Maria Lucrécia Zavaschi

    2002-11-01

    Full Text Available Objective. To determine the proportion of adolescents who have been exposed to physical violence in the city of Porto Alegre, Brazil. Methods. Fifty-two Porto Alegre public schools that offer basic primary education (grades 1 to 8 were selected through a random sampling process stratified according to school size. In May-November 2000 a screening survey that identifies exposure to violence¾experienced personally, witnessed, or knowing victims of violent acts¾was administered to all students who were attending a randomly selected 8th grade class in each of the 52 schools. Results. The total number of adolescents included in the analysis was 1 193, representing 10.3% of the students enrolled in 8th grade classes in the city's public school system. On average, each adolescent had been exposed to 19.8 incidents of violence (standard deviation (SD = 8.5: 2.0 incidents personally experienced (SD = 2.1, 8.5 incidents witnessed (SD = 4.0, and 9.3 knowing a victim of an incident of violence (SD = 4.1. In our sample, the variables of being male (P Objetivos. Determinar la proporción de adolescentes que han estado expuestos a la violencia física en la ciudad de Porto Alegre, Brasil. Métodos. Mediante un muestreo aleatorio estratificado en función del tamaño de la escuela, se seleccionaron 52 escuelas públicas de educación básica primaria (grados 1 a 8 de la ciudad de Porto Alegre. De mayo a noviembre del año 2000 se realizó una encuesta sobre la exposición a la violencia entre todos los estudiantes de una clase de octavo grado seleccionada aleatoriamente en cada una de las 52 escuelas. Como exposición a la violencia se consideró el haberla sufrido personalmente, el haberla presenciado o el conocer a víctimas de actos violentos. Resultados. En el análisis se incluyeron 1 193 adolescentes que representaban 10,3% de los estudiantes de octavo grado de las escuelas del sistema de enseñanza pública de la ciudad. En promedio (± desviación est

  11. Potential for Pharmacy-Public Health Collaborations Using Pharmacy-Based Point-of-Care Testing Services for Infectious Diseases.

    Science.gov (United States)

    Gubbins, Paul O; Klepser, Michael E; Adams, Alex J; Jacobs, David M; Percival, Kelly M; Tallman, Gregory B

    Health care professionals must continually identify collaborative ways to combat antibiotic resistance while improving community health and health care delivery. Clinical Laboratory Improvement Amendments of 1988 (CLIA)-waived point-of-care (POC) testing (POCT) services for infectious disease conducted in community pharmacies provide a means for pharmacists to collaborate with prescribers and/or public health officials combating antibiotic resistance while improving community health and health care delivery. To provide a comprehensive literature review that explores the potential for pharmacists to collaborate with public health professionals and prescribers using pharmacy-based CLIA-waived POCT services for infectious diseases. Comprehensive literature review. PubMed and Google Scholar were searched for manuscripts and meeting abstracts for the following key words: infectious disease, community pharmacy, rapid diagnostic tests, rapid assay, and POC tests. All relevant manuscripts and meeting abstracts utilizing POCT in community pharmacies for infectious disease were reviewed. Information regarding the most contemporary evidence regarding CLIA-waived POC infectious diseases tests for infectious diseases and their use in community pharmacies was synthesized to highlight and identify opportunities to develop future collaborations using community pharmacy-based models for such services. Evidence demonstrates that pharmacists in collaboration with other health care professionals can leverage their knowledge and accessibility to provide CLIA-waived POCT services for infectious diseases. Testing for influenza may augment health departments' surveillance efforts, help promote rationale antiviral use, and avoid unnecessary antimicrobial therapy. Services for human immunodeficiency virus infection raise infection status awareness, increase access to health care, and facilitate linkage to appropriate care. Testing for group A streptococcal pharyngitis may curb inappropriate

  12. Coliform Contamination of Peri-urban Grown Vegetables and Potential Public Health Risks: Evidence from Kumasi, Ghana.

    Science.gov (United States)

    Abass, Kabila; Ganle, John Kuumuori; Adaborna, Eric

    2016-04-01

    Peri-urban vegetable farming in Ghana is an important livelihood activity for an increasing number of people. However, increasing quality and public health concerns have been raised, partly because freshwater availability for irrigation purposes is a major constraint. This paper investigated on-farm vegetable contamination and potential health risks using samples of lettuce, spring onions and cabbage randomly selected from 18 vegetable farms in peri-urban Kumasi, Ghana. Vegetable samples were tested for total coliform, fecal coliform, Escherichia coli and Salmonella spp. bacteria contamination using the Most Probable Number method. Results show high contamination levels of total and fecal coliforms, and Escherichia coli bacteria in all 18 vegetable samples. The mean total coliform/100 ml concentration for spring onions, lettuce and cabbage were 9.15 × 10(9), 4.7 × 10(7) and 8.3 × 10(7) respectively. The mean fecal coliform concentration for spring onions, lettuce and cabbage were also 1.5 × 10(8), 4.15 × 10(7) and 2.15 × 10(7) respectively, while the mean Escherichia coli bacteria contamination for spring onions, lettuce and cabbage were 1.4 × 10(8), 2.2 × 10(7) and 3.2 × 10(7) respectively. The level of total coliform, fecal coliform and Escherichia coli bacteria contamination in all the vegetable samples however declined as the distance between the main water source (Wiwi River) and farms increases. Nonetheless, all contamination levels were well above acceptable standards, and could therefore pose serious public health risks to consumers. Increased education and supervision of farmers, as well as public health and food hygiene education of consumers, are critical to reducing on-farm vegetable contamination and the health risks associated with consumption of such vegetables.

  13. Direct-to-consumer pharmaceutical advertising: physician and public opinion and potential effects on the physician-patient relationship.

    Science.gov (United States)

    Robinson, Andrew R; Hohmann, Kirsten B; Rifkin, Julie I; Topp, Daniel; Gilroy, Christine M; Pickard, Jeffrey A; Anderson, Robert J

    2004-02-23

    Previous studies have shown that direct-to-consumer (DTC) pharmaceutical advertising can influence consumer behavior and that many physicians have negative views of these advertisements. Physician and public opinions about these advertisements and how they may affect the physician-patient relationship are not well established. Mail survey of 523 Colorado physicians and 261 national physicians and telephone survey of 500 Colorado households asking respondents to rate their agreement with statements about DTC advertising. Most physicians tended to view DTC advertisements negatively, indicating that such advertisements rarely provide enough information on cost (98.7%), alternative treatment options (94.9%), or adverse effects (54.8%). Most also believed that DTC advertisements affected interactions with patients by lengthening clinical encounters (55.9%), leading to patient requests for specific medications (80.7%), and changing patient expectations of physicians' prescribing practices (67.0%). Only 29.0% of public respondents agreed that DTC advertising is a positive trend in health care and 28.6% indicated that advertisements make them better informed about medical problems; fewer indicated that advertisements motivated them to seek care (10.5%) or led them to request specific medications from their physicians (13.3%). Most physicians have negative views of DTC pharmaceutical advertising and see several potential effects of these advertisements on the physician-patient relationship. Many public respondents have similarly negative views, and only a few agree that they change their expectations of or interactions with physicians. While these advertisements may be influencing only a few consumers, it seems that the impact on physicians and their interactions with patients may be significant.

  14. Proposed nomination of Yucca Mountain as a potential high-level radioactive waste repository. Correspondence and request for oral presentations for US Department of Energy public hearings

    International Nuclear Information System (INIS)

    1983-01-01

    This volume contains correspondence and requests by the public citizens for oral presentation at the public hearings for the proposed nomination of Yucca Mountain as a potential high-level radioactive waste repository. Written comments are also included on: the proposed nomination; the issues to be addressed in the Environmental Assessment; and the issues to be addressed by any Site Characterization Plan, if developed

  15. Children’s Caregivers and Public Playgrounds: Potential Reservoirs of Infection of Hand-foot-and-mouth Disease

    Science.gov (United States)

    Li, Pengyuan; Li, Tao; Gu, Qiuyun; Chen, Xiaomin; Li, Jiahui; Chen, Xiashi; Chen, Yan; Zhang, Danwei; Gao, Rong; He, Zhenjian; Zhu, Xun; Zhang, Wangjian; Hao, Yuantao; Zhang, Dingmei

    2016-11-01

    Hand-foot-and-mouth disease (HFMD) is a common infectious disease, which has led to millions of clinical cases and hundreds of deaths every year in China. This study aimed to exploring the effects on HFMD transmission of children’s caregivers and public area, as well as trying to locate the potential reservoirs of infections in primary cases. Total children’s 257 samples (98 children’s caregivers and 159 environmental samples) were tested for the presence of universal enterovirus, enterovirus 71, coxsackie virus A6 and A16 by real-time fluorescence quantitative polymerase chain reaction (qPCR). 5.84% (15/257, 95% confidence interval [CI]: 2.98%, 8.70%) of total samples had positive results of enterovirus. The enterovirus positive rates of children’s caregiver samples and environmental samples were respectively 7.14% (7/98, 95% CI: 2.04%, 12.24%), and 5.03% (8/159, 95% CI: 1.63%, 8.43%); 7.61% (7/92, 95% CI: 2.21%, 13.01%) of wiping samples from playgrounds and 1.49% (1/67, 95% CI: 0, 7.00%) of air samples in indoor market places had positive result of enterovirus. High positive rates of enterovirus in children’s caregivers and from playgrounds indicated that they would be potential reservoirs of HFMD infection, as children might be infected via contacting with asymptomatic-infected individuals or exposure of contaminated surface of public facilities.

  16. Optimization at the design phase of the potential impact of ITER on workers, the public and the environment

    Energy Technology Data Exchange (ETDEWEB)

    Cortes, Pierre, E-mail: pierre.cortes@iter.or [ITER Organization, CS 9 0046, 13067 St Paul lez Durance (France); Taylor, Neill; Rosanvallon, Sandrine; Rodriguez-Rodrigo, Lina; Elbez-Uzan, Joelle; Iseli, Markus; Ciattaglia, Sergio [ITER Organization, CS 9 0046, 13067 St Paul lez Durance (France)

    2010-12-15

    This paper presents an overview of the approach followed during the design phase of ITER to reduce and optimize the potential impact of ITER construction, operation and dismantling on workers, on the population and on the environment in normal situation. ITER will use and create some toxic and radiotoxic materials. Tritium will be used as part of its fuelling, and beryllium on plasma facing components. Dust will be produced in plasma operation in the vacuum vessel as well as activated corrosion products in the primary cooling circuits. Thus, small quantities of releases of the toxic and radioactive materials in the environment could not be excluded. In order to ensure the compliance of ITER licensing with French regulations, the ITER design has to demonstrate that the safety of workers, the environment and members of the public is ensured following not only international regulations but also the three principles mentioned in the French Public Health Code: principles of justification of the activities, of limitation of consequences below authorised limits and of optimization. The ITER teams involved in the design of systems and structures have the permanent goals to ensure this compliance with French regulations in particular to reduce, as far as reasonably achievable, the impact of ITER activities on workers, the public and on the environment and to show that this meets the optimization principle. This optimization process is one of the major ITER safety challenges and has required a great effort of optimization, incorporated iteratively into the design, since the beginning. This will be notably reached through several provisions such as the adequate selection of materials, the reduction, close control and monitoring of radioactive inventories, the confinement of radioactive and toxic materials, layout and shielding design, the remote handling capability, the operating and maintenance procedures. The main activities for which an optimization process is used include

  17. Optimization at the design phase of the potential impact of ITER on workers, the public and the environment

    International Nuclear Information System (INIS)

    Cortes, Pierre; Taylor, Neill; Rosanvallon, Sandrine; Rodriguez-Rodrigo, Lina; Elbez-Uzan, Joelle; Iseli, Markus; Ciattaglia, Sergio

    2010-01-01

    This paper presents an overview of the approach followed during the design phase of ITER to reduce and optimize the potential impact of ITER construction, operation and dismantling on workers, on the population and on the environment in normal situation. ITER will use and create some toxic and radiotoxic materials. Tritium will be used as part of its fuelling, and beryllium on plasma facing components. Dust will be produced in plasma operation in the vacuum vessel as well as activated corrosion products in the primary cooling circuits. Thus, small quantities of releases of the toxic and radioactive materials in the environment could not be excluded. In order to ensure the compliance of ITER licensing with French regulations, the ITER design has to demonstrate that the safety of workers, the environment and members of the public is ensured following not only international regulations but also the three principles mentioned in the French Public Health Code: principles of justification of the activities, of limitation of consequences below authorised limits and of optimization. The ITER teams involved in the design of systems and structures have the permanent goals to ensure this compliance with French regulations in particular to reduce, as far as reasonably achievable, the impact of ITER activities on workers, the public and on the environment and to show that this meets the optimization principle. This optimization process is one of the major ITER safety challenges and has required a great effort of optimization, incorporated iteratively into the design, since the beginning. This will be notably reached through several provisions such as the adequate selection of materials, the reduction, close control and monitoring of radioactive inventories, the confinement of radioactive and toxic materials, layout and shielding design, the remote handling capability, the operating and maintenance procedures. The main activities for which an optimization process is used include

  18. The potential global market size and public health value of an HIV-1 vaccine in a complex global market.

    Science.gov (United States)

    Marzetta, Carol A; Lee, Stephen S; Wrobel, Sandra J; Singh, Kanwarjit J; Russell, Nina; Esparza, José

    2010-07-05

    An effective HIV vaccine will be essential for the control of the HIV pandemic. This study evaluated the potential global market size and value of a hypothetical HIV vaccine and considered clade diversity, disease burden, partial prevention of acquisition, impact of a reduction in viral load resulting in a decrease in transmission and delay to treatment, health care system differences regarding access, and HIV screening and vaccination, across all public and private markets. Vaccine product profiles varied from a vaccine that would have no effect on preventing infection to a vaccine that would effectively prevent infection and reduce viral load. High disease burden countries (HDBC; HIV prevalence > or = 1%) were assumed to routinely vaccinate pre-sexually active adolescents (10 years old), whereas low disease burden countries (LDBC; HIV prevalence rate market value of $210 million to $2.7 billion, depending on the vaccine product profile. If one-time catch-up campaigns were included (11-14 years old for HDBC and higher risk groups for LDBC), the additional cumulative approximately 70-237 million doses were needed over a 10-year period with a potential market value of approximately $695 million to $13.4 billion, depending on the vaccine product profile. Market size and value varied across market segments with the majority of the value in high income countries and the majority of the demand in low income countries. However, the value of the potential market in low income countries is still significant with up to $550 million annually for routine vaccination only and up to $1.7 billion for a one-time only catch-up campaign in 11-14 years old. In the most detail to date, this study evaluated market size and value of a potential multi-clade HIV vaccine, accounting for differences in disease burden, product profile and health care complexities. These findings provide donors and suppliers highly credible new data to consider in their continued efforts to develop an HIV-1

  19. The role of public service motivation in performance : Examining the potentials and pitfalls through an institutional approach

    NARCIS (Netherlands)

    van Loon, N.M.

    2015-01-01

    Does feeling a motivational drive to contribute to society matter for the performance of public employees? This dissertation shows it does: employees that are highly public service motivated perform better in their job, are more likely to help their colleagues and work units with highly public

  20. General Approach to Identifying Potential Targets for Cancer Imaging by Integrated Bioinformatics Analysis of Publicly Available Genomic Profiles

    Directory of Open Access Journals (Sweden)

    Yongliang Yang

    2011-03-01

    Full Text Available Molecular imaging has moved to the forefront of drug development and biomedical research. The identification of appropriate imaging targets has become the touchstone for the accurate diagnosis and prognosis of human cancer. Particularly, cell surface- or membrane-bound proteins are attractive imaging targets for their aberrant expression, easily accessible location, and unique biochemical functions in tumor cells. Previously, we published a literature mining of potential targets for our in-house enzyme-mediated cancer imaging and therapy technology. Here we present a simple and integrated bioinformatics analysis approach that assembles a public cancer microarray database with a pathway knowledge base for ascertaining and prioritizing upregulated genes encoding cell surface- or membrane-bound proteins, which could serve imaging targets. As examples, we obtained lists of potential hits for six common and lethal human tumors in the prostate, breast, lung, colon, ovary, and pancreas. As control tests, a number of well-known cancer imaging targets were detected and confirmed by our study. Further, by consulting gene-disease and protein-disease databases, we suggest a number of significantly upregulated genes as promising imaging targets, including cell surface-associated mucin-1, prostate-specific membrane antigen, hepsin, urokinase plasminogen activator receptor, and folate receptors. By integrating pathway analysis, we are able to organize and map “focused” interaction networks derived from significantly dysregulated entity pairs to reflect important cellular functions in disease processes. We provide herein an example of identifying a tumor cell growth and proliferation subnetwork for prostate cancer. This systematic mining approach can be broadly applied to identify imaging or therapeutic targets for other human diseases.

  1. Estimating the Potential Risks of Sea Level Rise for Public and Private Property Ownership, Occupation and Management

    Directory of Open Access Journals (Sweden)

    Georgia Warren-Myers

    2018-04-01

    Full Text Available The estimation of future sea level rise (SLR is a major concern for cities near coastlines and river systems. Despite this, current modelling underestimates the future risks of SLR to property. Direct risks posed to property include inundation, loss of physical property and associated economic and social costs. It is also crucial to consider the risks that emerge from scenarios after SLR. These may produce one-off or periodic events that will inflict physical, economic and social implications, and direct, indirect and consequential losses. Using a case study approach, this paper combines various forms of data to examine the implications of future SLR to further understand the potential risks. The research indicates that the financial implications for local government will be loss of rates associated with total property loss and declines in value. The challenges identified are not specific to this research. Other municipalities worldwide experience similar barriers (i.e., financial implications, coastal planning predicaments, data paucity, knowledge and capacity, and legal and political challenges. This research highlights the need for private and public stakeholders to co-develop and implement strategies to mitigate and adapt property to withstand the future challenges of climate change and SLR.

  2. Performance of biomarkers SMRP, CA125, and CYFRA 21-1 as potential tumor markers for malignant mesothelioma and lung cancer in a cohort of workers formerly exposed to asbestos

    International Nuclear Information System (INIS)

    Gube, M.; Taeger, D.; Weber, D.G.; Pesch, B.; Johnen, G.; Gross, I.M.; Wiethege, T.; Weber, A.; Bruening, T.; Brand, P.; Mueller-Lux, A.; Kraus, T.; Raithel, H.J.

    2011-01-01

    The aim of the study is to examine the cancer-predictive values of SMRP (soluble mesothelin-related peptides), CA125, and CYFRA21-1 as potential tumor markers for lung cancer and malignant mesothelioma in a cohort of workers formerly exposed to asbestos. A voluntary surveillance program has been established for German workers with former asbestos exposure. A subgroup of 626 subjects with a mean age of 63 years (range 53-70 years) at baseline was enrolled in an extended health examination program with high-resolution computer tomography (HRCT) of the chest and blood drawing between 1993 and 1997. Serum concentrations of SMRP, CA125, and CYFRA21-1 were measured in archived serum samples in 2005 and 2006. A mortality follow-up was conducted through 2007. So far, 12 cases with lung cancer and 20 cases with malignant mesothelioma have been observed in this cohort. The average time between sample collection and diagnosis was 4.7 years. Analyzed biomarkers showed low sensitivities (5-25%) and positive predictive values (4-30%) for both cancer sites. Marker combinations resulted in sensitivities between 5 and 50% and positive predictive values ranging from 3 to 14%. Even in those cases, where biomarker concentrations were available within 36 months before diagnosis, no trend for increasing biomarker levels was observed. The analyzed tumor markers were characterized by high specificities, but low sensitivities. SMRP, CA125, and CYFRA21-1 alone or in combination were less suitable to serve as predictors for the diagnosis of lung cancer or malignant mesothelioma. However, a prospective study with annual sampling might reveal a better predictive value of these markers. (orig.)

  3. Performance of biomarkers SMRP, CA125, and CYFRA 21-1 as potential tumor markers for malignant mesothelioma and lung cancer in a cohort of workers formerly exposed to asbestos

    Energy Technology Data Exchange (ETDEWEB)

    Gube, M. [RWTH Aachen University, Institute for Occupational and Social Medicine, Medical Faculty, Aachen (Germany); Westfaelische Technische Hochschule, Institut fuer Arbeitsmedizin und Sozialmedizin am Universitaetsklinikum Aachen, Rheinisch, Aachen (Germany); Taeger, D.; Weber, D.G.; Pesch, B.; Johnen, G.; Gross, I.M.; Wiethege, T.; Weber, A.; Bruening, T. [Institute of the Ruhr-Universitaet Bochum (IPA), Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Bochum (Germany); Brand, P.; Mueller-Lux, A.; Kraus, T. [RWTH Aachen University, Institute for Occupational and Social Medicine, Medical Faculty, Aachen (Germany); Raithel, H.J. [University of Erlangen-Nuremberg, Institute for Occupational, Social and Environmental Medicine, Erlangen-Nuremberg (Germany)

    2011-03-15

    The aim of the study is to examine the cancer-predictive values of SMRP (soluble mesothelin-related peptides), CA125, and CYFRA21-1 as potential tumor markers for lung cancer and malignant mesothelioma in a cohort of workers formerly exposed to asbestos. A voluntary surveillance program has been established for German workers with former asbestos exposure. A subgroup of 626 subjects with a mean age of 63 years (range 53-70 years) at baseline was enrolled in an extended health examination program with high-resolution computer tomography (HRCT) of the chest and blood drawing between 1993 and 1997. Serum concentrations of SMRP, CA125, and CYFRA21-1 were measured in archived serum samples in 2005 and 2006. A mortality follow-up was conducted through 2007. So far, 12 cases with lung cancer and 20 cases with malignant mesothelioma have been observed in this cohort. The average time between sample collection and diagnosis was 4.7 years. Analyzed biomarkers showed low sensitivities (5-25%) and positive predictive values (4-30%) for both cancer sites. Marker combinations resulted in sensitivities between 5 and 50% and positive predictive values ranging from 3 to 14%. Even in those cases, where biomarker concentrations were available within 36 months before diagnosis, no trend for increasing biomarker levels was observed. The analyzed tumor markers were characterized by high specificities, but low sensitivities. SMRP, CA125, and CYFRA21-1 alone or in combination were less suitable to serve as predictors for the diagnosis of lung cancer or malignant mesothelioma. However, a prospective study with annual sampling might reveal a better predictive value of these markers. (orig.)

  4. Fire exposed aluminium structures

    NARCIS (Netherlands)

    Maljaars, J.; Fellinger, J.E.J.; Soetens, F.

    2005-01-01

    Material properties and mechanical response models for fire design of steel structures are based on extensive research and experience. Contrarily, the behaviour of aluminium load bearing structures exposed to fire is relatively unexplored. This article gives an overview of physical and mechanical

  5. Pathogenic multiple antimicrobial resistant Escherichia coli serotypes in recreational waters of Mumbai, India: A potential public health risk

    Digital Repository Service at National Institute of Oceanography (India)

    Maloo A.; Fulke, A.B.; Mulani, N.; Sukumaran, S.; Ram, A.

    , government authorities and environmental planners should create public awareness and adopt effective measures for coastal management to prevent serious health risks associated with these contaminated coastal waters....

  6. The potential of public engagement in sustainable waste management: designing the future for biosolids in New Zealand.

    Science.gov (United States)

    Goven, Joanna; Lisa Langer, E R

    2009-02-01

    Strategies for beneficial use of biosolids in New Zealand and elsewhere are currently focused primarily on land application. The long-term success of these and other strategies is dependent not only on technical factors, but also on their environmental, economic, social and cultural sustainability. This paper briefly reviews the situation with respect to biosolids management in New Zealand, where land application is not yet widespread; the rise in public opposition to land application in the United States; and the biosolids industry's approach to public engagement. We argue that, at least until recently, the industry has misinterpreted the nature and meaning of public opposition and thus substituted public relations for public engagement. We argue that genuine public engagement is necessary and that its purpose cannot be to gain public acceptance for an already-decided-upon strategy. It therefore calls for humility among biosolids managers, including a willingness to open up the framing of 'the problem', to acknowledge areas of uncertainty, and to recognise the role of values in 'technical' decision-making. We then present and analyse an example of the use of the scenario workshop process for public participation in biosolids management policy in Christchurch, New Zealand, and conclude that scenario workshops and related methods represent an opportunity to enhance sustainable waste management when certain conditions are met.

  7. Measuring risk/benefit perceptions of emerging technologies and their potential impact on communication of public opinion toward science.

    Science.gov (United States)

    Binder, Andrew R; Cacciatore, Michael A; Scheufele, Dietram A; Shaw, Bret R; Corley, Elizabeth A

    2012-10-01

    This study presents a systematic comparison of two alternative measures of citizens' perceptions of risks and benefits of emerging technologies. By focusing on two specific issues (nanotechnology and biofuels), we derive several insights for the measurement of public views of science. Most importantly, our analyses reveal that relying on global, single-item measures may lead to invalid inferences regarding external influences on public perceptions, particularly those related to cognitive schema and media use. Beyond these methodological implications, this analysis suggests several reasons why researchers in the area of public attitudes toward science must revisit notions of measurement in order to accurately inform the general public, policymakers, scientists, and journalists about trends in public opinion toward emerging technologies.

  8. The Potential to Forgo Social Welfare Gains through Over reliance on Cost Effectiveness/Cost Utility Analyses in the Evidence Base for Public Health

    International Nuclear Information System (INIS)

    Cohen, D.R.; Patel, N.

    2010-01-01

    Economic evaluations of clinical treatments most commonly take the form of cost effectiveness or cost utility analyses. This is appropriate since the main sometimes the only benefit of such interventions is increased health. The majority of economic evaluations in public health, however, have also been assessed using these techniques when arguably cost benefit analyses would in many cases have been more appropriate, given its ability to take account of non health benefits as well. An examination of the non health benefits from a sample of studies featured in a recent review of economic evaluations in public health illustrates how over focusing on cost effectiveness/cost utility analyses may lead to forgoing potential social welfare gains from programmes in public health. Prior to evaluation, programmes should be considered in terms of the potential importance of non health benefits and where these are considerable would be better evaluated by more inclusive economic evaluation techniques.

  9. InfoRio, focus group sessions to test potential for a personal real time travel information concept for public transport, (no 03071, 23 p.)

    NARCIS (Netherlands)

    Vonk, W.G.; Vonk, Warner; Nijenhuis, Guido; van Berkum, Eric C.; Bodmer, Milena; Hulleman, Robert; Hulleman, R.; Viegas, J.M.; Macario, R.

    2010-01-01

    This paper describes the development of a market research method in order to establish the potential demand for a Personal Real Time Travel Information (PRTTI) concept applied to public transport (PT) in Rio de Janeiro, called InfoRio. In order to receive personal travel information on PT services

  10. Potential public health impact of RTS,S malaria candidate vaccine in sub-Saharan Africa: a modelling study.

    Science.gov (United States)

    Sauboin, Christophe J; Van Bellinghen, Laure-Anne; Van De Velde, Nicolas; Van Vlaenderen, Ilse

    2015-12-23

    Adding malaria vaccination to existing interventions could help to reduce the health burden due to malaria. This study modelled the potential public health impact of the RTS,S candidate malaria vaccine in 42 malaria-endemic countries in sub-Saharan Africa. An individual-based Markov cohort model was constructed with three categories of malaria transmission intensity and six successive malaria immunity levels. The cycle time was 5 days. Vaccination was assumed to reduce the risk of infection, with no other effects. Vaccine efficacy was assumed to wane exponentially over time. Malaria incidence and vaccine efficacy data were taken from a Phase III trial of the RTS,S vaccine with 18 months of follow-up (NCT00866619). The model was calibrated to reproduce the malaria incidence in the control arm of the trial in each transmission category and published age distribution data. Individual-level heterogeneity in malaria exposure and vaccine protection was accounted for. Parameter uncertainty and variability were captured by using stochastic model transitions. The model followed a cohort from birth to 10 years of age without malaria vaccination, or with RTS,S malaria vaccination administered at age 6, 10 and 14 weeks or at age 6, 7-and-a-half and 9 months. Median and 95% confidence intervals were calculated for the number of clinical malaria cases, severe cases, malaria hospitalizations and malaria deaths expected to be averted by each vaccination strategy. Univariate sensitivity analysis was conducted by varying the values of key input parameters. Vaccination assuming the coverage of diphtheria-tetanus-pertussis (DTP3) at age 6, 10 and 14 weeks is estimated to avert over five million clinical malaria cases, 119,000 severe malaria cases, 98,600 malaria hospitalizations and 31,000 malaria deaths in the 42 countries over the 10-year period. Vaccination at age 6, 7-and-a-half and 9 months with 75% of DTP3 coverage is estimated to avert almost 12.5 million clinical malaria cases

  11. Chemical mixtures in untreated water from public-supply wells in the U.S. — Occurrence, composition, and potential toxicity

    International Nuclear Information System (INIS)

    Toccalino, Patricia L.; Norman, Julia E.; Scott, Jonathon C.

    2012-01-01

    Chemical mixtures are prevalent in groundwater used for public water supply, but little is known about their potential health effects. As part of a large-scale ambient groundwater study, we evaluated chemical mixtures across multiple chemical classes, and included more chemical contaminants than in previous studies of mixtures in public-supply wells. We (1) assessed the occurrence of chemical mixtures in untreated source-water samples from public-supply wells, (2) determined the composition of the most frequently occurring mixtures, and (3) characterized the potential toxicity of mixtures using a new screening approach. The U.S. Geological Survey collected one untreated water sample from each of 383 public wells distributed across 35 states, and analyzed the samples for as many as 91 chemical contaminants. Concentrations of mixture components were compared to individual human-health benchmarks; the potential toxicity of mixtures was characterized by addition of benchmark-normalized component concentrations. Most samples (84%) contained mixtures of two or more contaminants, each at concentrations greater than one-tenth of individual benchmarks. The chemical mixtures that most frequently occurred and had the greatest potential toxicity primarily were composed of trace elements (including arsenic, strontium, or uranium), radon, or nitrate. Herbicides, disinfection by-products, and solvents were the most common organic contaminants in mixtures. The sum of benchmark-normalized concentrations was greater than 1 for 58% of samples, suggesting that there could be potential for mixtures toxicity in more than half of the public-well samples. Our findings can be used to help set priorities for groundwater monitoring and suggest future research directions for drinking-water treatment studies and for toxicity assessments of chemical mixtures in water resources. - Highlights: ► We assessed mixtures in untreated groundwater samples from public-supply wells. ► A screening

  12. RETRACTED M-HEALTH SERVICES: CAN IT BE A POTENTIAL MECHANISM IN IMPROVING PUBLIC HEALTH SYSTEM OF INDIA?

    Directory of Open Access Journals (Sweden)

    Sanjeev Davey

    2013-09-01

    Full Text Available Background: The role of mobile in health system is now important for us, to make use of this very fastly growing technology in improving the public health of Indian people. Objectives: To critically review the role of m-health in public health system of India. Methods: A systematic review of related studies and literature of last 10 years published in pubmed etc till 31st March 2013 on role of m-Health in public health was done. Results and discussion: A wide variety of m-health applications are available in mobile phone market, needing proper regulation from health care authorities and with a hope of better future results. Recommendations: We must use these applications weighing their benefits and utility in public health as well as capitalizing the better prospect of m-health worldwide in the field of public health. This can give a greater access to larger segments of a rural and underserved population in developing countries like India with a hope of improving the capacity of health system to provide quality healthcare to Indian people.

  13. Retrospective genetic study of germinative mutations in Str loci of individuals potentially exposed to ionizing radiation;Estudo genetico retrospectivo de mutacoes germinativas em Loci Str de individuos potencialmente expostos a radiacao ionizante

    Energy Technology Data Exchange (ETDEWEB)

    Costa, Emilia Oliveira Alves

    2010-07-01

    The Brazilian radiological accident that occurred in 1987, in Goiania, it was a terrible radiation episode. As a consequence, hundreds of people were contaminated due to the Cesium-137 radiation. Recently, many studies had shown that genome instabilities, such as, mutations, chromosomal aberrations, micronuclei formation and micro satellite instability and a delay on cellular death are usually reported on mammal cells exposed to ionizing radiation, being considered as a manly risk to humans. Mutations can be spontaneous, and the occurrence is dependent on the organism, or, induced, being associated to mutagenic exposition. Ionizing radiations are an example of physical and mutagenic agents that could harm the cell repair and could cause the development of many types of cancer. The evaluation of the biological effects of the ionizing radiation, in somatic and germ line cells, with a consequent determination of the radio-induced mutations, it is extremely important to estimate the genetic risks, manly in population exposed to radiation. The analyses of repetitive DNA sequences have been demonstrated that such sequences are prone to high rates of spontaneous mutations. The minisatellites and microsatellites have been used to demonstrate the induction of germ line mutation rates on mouse, humans, among others organisms. The aim of the present study was to analyze the frequency of microsatellite alterations to determine the mutation rates occurred in germ cells of the parents exposed to the ionizing radiation of the Cesium-137. The studied group was constitute of 10 families of individuals accidentally exposed to Cesium-137 and by the control group constituted by 645 healthy individuals who carried out paternity tests on 2009. We found only one mutation of paternal origin in the D8S1179 locus on the exposed group, being the mutation rate of 0.002. In the control group, we found 01 mutation on D16S539 loei and on D3S1358; 02 mutations on Penta E loeus; 04 mutations on D

  14. Assessment of the Effects of Acute and Repeated Exposure to Blast Overpressure in Rodents: Towards a Greater Understanding of Blast and the Potential Ramifications for Injury in Humans Exposed to Blast

    Directory of Open Access Journals (Sweden)

    Stephen Thomas Ahlers

    2012-03-01

    Full Text Available Mild traumatic brain injury (mTBI resulting from exposure to improvised explosive devices (IEDs has fueled a requirement to develop animals models that mirror this condition using exposure to blast overpressure (BOP. En route to developing a model of repeated exposure to BOP we sought to initially characterize the effects of acute BOP exposure in rodents, focusing specifically on the levels of BOP exposure that produced clinical mTBI symptoms. We first measured BOP effects on gross motor function on a balance beam. Separate groups of unanesthetized rats were exposed (in different orientations to 40 kPa, 75 kPa and 120 kPa BOP exposure inside a pneumatically driven shock tube. Results demonstrated that rats exposed to 120 kPa demonstrated transient alterations or loss of consciousness indicated by a transient loss of righting and by increased latencies on the balance beam. The 120 kPa exposure was the threshold for overt pathology for acute BOP exposure with approximately 30% of rats presenting with evidence of subdural hemorrhage and cortical contusions. All animals exposed to 120 kPa BOP manifested evidence of significant pulmonary hemorrhage. Anterograde memory deficits were observed in rats exposed to 75 kPa facing the BOP wave and rats exposed to 120 kPa in the lateral (side orientation. We next assessed repeated exposure to either lateral or frontal 40 kPa BOP in anesthetized rats, once per day for 12 days. Results showed that repeated exposure in the frontal, but not side, orientation to the BOP wave produced a transitory learning deficit on a Morris water maze (MWM task as shown by significantly longer latencies to reach the submerged platform in the second and third blocks of a four block session. Implications of these data are discussed in relation to the manifestation of mTBI in military personnel exposed to IEDs. Finally, we suggest that there are multiple types of brain injury from blast.

  15. Preventing evictions as a potential public health intervention: Characteristics and social medical risk factors of households at risk in Amsterdam

    NARCIS (Netherlands)

    van Laere, Igor; de Wit, Matty; Klazinga, Niek S.

    2009-01-01

    Aims: The public health problems precipitating evictions are understudied and no systemic data have been collected. We aim to identify the magnitude of evictions and the characteristics and social medical risk factors of households at risk in Amsterdam. This will help inform policies designed to

  16. Just the Right Mix: Identifying Potential Dropouts in Montgomery County Public Schools Using an Early Warning Indicators Approach

    Science.gov (United States)

    West, Thomas C.

    2013-01-01

    Each school year, roughly a thousand students drop out of Montgomery County (Maryland) Public Schools (MCPS). However, unlike other large, urban school districts where students who drop out skip school and are suspended often (Balfanz & Byrnes, 2010), students who drop out of MCPS are present in school; they just are not doing well…

  17. 78 FR 28495 - Safety Zone; Safety Precautions to Protect the Public from the Effects of a Potential...

    Science.gov (United States)

    2013-05-15

    ... environmental risk to health or risk to safety that might disproportionately affect children. 10. Indian Tribal... and port recovery operations in this part of the Illinois River, and the potential structural concerns... from the hazards associated with salvage and port recovery operations and the potential catastrophic...

  18. Particle (Soot Pollution in Port Harcourt Rivers State, Nigeria—Double Air Pollution Burden? Understanding and Tackling Potential Environmental Public Health Impacts

    Directory of Open Access Journals (Sweden)

    Okhumode H. Yakubu

    2017-12-01

    Full Text Available Residents of Port Harcourt in Rivers State, Nigeria, and its environs have since the last quarter of 2016 been experiencing adverse environmental impacts of particle (soot pollution. This “double air pollution burden”—the unresolved prevailing widespread air pollution and the “added” emergence of particle pollution considered an environmental health threat, led to protests against government inaction in some parts of the state. In February 2017, several months following the onset of the pollution, the government declared an Emergency, and set up a Task Force to investigate and find a solution to the problem. Global research suggests that particle pollution correlates positively with a range of morbidities and an increased risk of mortality among exposed populations. This underscores the need for rigorous implementation of existing environmental legislations established to protect the environment and public health. Nigeria’s rapid response to the 2014–2015 Ebola Virus Disease (EVD and successful prevention of its spread provides some lessons for addressing such environmental health emergencies—strategic action, including effective environmental risk communication, environmental audit, and monitoring is key. Epidemiological studies of the affected population is imperative. A concerted effort by the Rivers State Ministries of Environment and Health, as well as academia and private organizations is required. Public service campaign in terms of government providing up to date information on the existing situation is required.

  19. District decision-making for health in low-income settings: a case study of the potential of public and private sector data in India and Ethiopia

    Science.gov (United States)

    Bhattacharyya, Sanghita; Berhanu, Della; Taddesse, Nolawi; Srivastava, Aradhana; Wickremasinghe, Deepthi; Schellenberg, Joanna

    2016-01-01

    Many low- and middle-income countries have pluralistic health systems where private for-profit and not-for-profit sectors complement the public sector: data shared across sectors can provide information for local decision-making. The third article in a series of four on district decision-making for health in low-income settings, this study shows the untapped potential of existing data through documenting the nature and type of data collected by the public and private health systems, data flow and sharing, use and inter-sectoral linkages in India and Ethiopia. In two districts in each country, semi-structured interviews were conducted with administrators and data managers to understand the type of data maintained and linkages with other sectors in terms of data sharing, flow and use. We created a database of all data elements maintained at district level, categorized by form and according to the six World Health Organization health system blocks. We used content analysis to capture the type of data available for different health system levels. Data flow in the public health sectors of both counties is sequential, formal and systematic. Although multiple sources of data exist outside the public health system, there is little formal sharing of data between sectors. Though not fully operational, Ethiopia has better developed formal structures for data sharing than India. In the private and public sectors, health data in both countries are collected in all six health system categories, with greatest focus on service delivery data and limited focus on supplies, health workforce, governance and contextual information. In the Indian private sector, there is a better balance than in the public sector of data across the six categories. In both India and Ethiopia the majority of data collected relate to maternal and child health. Both countries have huge potential for increased use of health data to guide district decision-making. PMID:27591203

  20. Examining the potential of information technology to improve public insurance application processes: enrollee assessments from a concurrent mixed method analysis.

    Science.gov (United States)

    Mishra, Abhay Nath; Ketsche, Patricia; Marton, James; Snyder, Angela; McLaren, Susan

    2014-01-01

    To assess the perceived readiness of Medicaid and Children's Health Insurance Program (CHIP) enrollees to use information technologies (IT) in order to facilitate improvements in the application processes for these public insurance programs. We conducted a concurrent mixed method study of Medicaid and CHIP enrollees in a southern state. We conducted focus groups to identify enrollee concerns regarding the current application process and their IT proficiency. Additionally, we surveyed beneficiaries via telephone about their access to and use of the Internet, and willingness to adopt IT-enabled processes. 2013 households completed the survey. We used χ(2) analysis for comparisons across different groups of respondents. A majority of enrollees will embrace IT-enabled enrollment, but a small yet significant group continues to lack access to facilitating technologies. Moreover, a segment of beneficiaries in the two programs continues to place a high value on personal interactions with program caseworkers. IT holds the promise of improving efficiency and reducing barriers for enrollees, but state and federal agencies managing public insurance programs need to ensure access to traditional processes and make caseworkers available to those who require and value such assistance, even after implementing IT-enabled processes. The use of IT-enabled processes is essential for effectively managing eligibility and enrollment determinations for public programs and private plans offered through state or federally operated exchanges. However, state and federal officials should be cognizant of the technological readiness of recipients and provide offline help to ensure broad participation in the insurance market. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  1. The exposed breast

    International Nuclear Information System (INIS)

    Ingman, Wendy

    2014-01-01

    The skin and lungs are two tissues that are frequently bombarded with cancer-initiating factors, such as ultraviolet rays from the sun and smoke and pollutants in the air we breathe. Yet breast cancer is the most common type of cancer in Australian women, affecting one in eight before the age of 85. It is more common than skin melanoma and lung cancer. Why, then, does the breast so commonly get cancer when it is not a tissue that is particularly exposed to the environmental agents that increase cancer risk in other major organs? Is there something unique about this tissue that makes it particularly susceptible? The breast undergoes cellular changes over the course of the monthly menstrual cycle, and and these changes affect cancer susceptibility. Rising levels of the hormones oestrogen and progesterone occur immediately after the egg is released from the ovary, and these hormones cause the breast cells to divide and change to accommodate further development if pregnancy occurs. If the woman becomes pregnant, the cells in the breast continue to develop and become the milk-producing structures required to feed a newborn baby. But if pregnancy does not occur there is a drop in progesterone, which triggers the death of the newly developed breast cells. This occurs at the same time women have their period. Then the cycle starts again, and continues every month until menopause, unless the woman becomes pregnant.

  2. Potential environmental effects of 765-kV transmission lines: views before the New York State Public Service Commission, Cases 26529 and 26559, 1976-1978

    Energy Technology Data Exchange (ETDEWEB)

    Scott-Walton, B.; Clark, K. M.; Holt, B. R.; Jones, D. C.; Kaplan, S. D.; Krebs, J. S.; Polson, P.; Shepherd, R. A.; Young, J. R.

    1979-11-01

    Testimony given before the New York Public Service Commission in two recent cases on the potential environmental effects of 765-kV overhead ac transmission lines is reviewed. The testimony focused on the potential effects of audible noise, on the potential biological effects of the electromagnetic fields, on the potential for electric shocks to people who touch vehicles parked under the proposed lines, on the potential effects of the electromagnetic fields on electronic cardiac pacemakers, and on potential effects of ozone produced by corona discharge from the lines. The testimony fully explored these questions; however, it did not resolve all of them. The testimony indicates potential impacts from the audible noise and from the electrostatic shocks that people can receive when they touch a large vehicle parked under the lines. The testimony also indicates that certain cardiac pacemaker and lead combinations may, under certain circumstances, undergo reversion to a fixed rate of pacing in the presence of the fields under the lines, but that little risk to cardiac patients results except possibly for those patients for whom competition between the heart's own rate and the pacemaker rate presents a health risk. The testimony fails to demonstrate biological hazards from the field; further research is necessary to understand better the effects of the fields on biological systems. The testimony indicates that ozone produced by the lines will not significantly affect the environment.

  3. Invasive forms of canine endoparasites as a potential threat to public health – A review and own studies

    Directory of Open Access Journals (Sweden)

    Mirosława Felsmann

    2017-05-01

    Full Text Available Dogs serve as the vectors of serious zoonotic parasitic diseases. In the month of May 2012 – 2014, 339 dog faeces samples from seven public sites in Chełmno, a town in northern Poland, were collected and examined to determine the gastrointestinal parasite fauna of dogs. Each faecal sample was dissected with a needle, checked for tapeworm segments and examined for parasite eggs and oocysts using the flotation and decantation method and a modified Baermann technique. Differences were observed in the degree of parasite species occurrence. The most dominant were Toxocara canis and Ancylostomatidae. The detected species included: T. canis and Toxascaris leonina eggs (23.4% and 10.2%, respectively, as well as eggs from the Ancylostomatidae family (16.2%, Trichuris vulpis eggs (6.6%, Taenia type eggs (4.6%, Dipylidium caninum (5.2% and Cystoisospora (Isospora spp. oocysts (10.9%.

  4. Theoretical and Methodological Aspects of Optimization of Relationship between Economic Potential and Sources for Public Needs Settlement

    Directory of Open Access Journals (Sweden)

    Stojanović Aleksandar

    2016-06-01

    Full Text Available The relative level of fiscal revenue in relation to the total aggregate domestic product or national income is a central indicator to be established in the national economy. This indicator is the “tax ratio”. The tendency of almost every economic and especially fiscal policy is that this indicator expresses the optimal ratio between the part of the domestic product or national income, which is intended to be used for the settlement of public needs and the general economic aggregate of the latter economic categories. Its special importance lies in the design concept of medium-term or long-term social and economic development. It is necessary to determine the framework of the global distribution of the domestic product or national income, which is acceptable, on the one hand, from the perspective of a balanced and stable economic growth, and on the other hand, from the standpoint of balancing interests of all social structures of modern mixed societies.

  5. Marker-assisted selection in maize: current status, potential, limitations and perspectives from the private and public sectors

    International Nuclear Information System (INIS)

    Ragot, M.; Lee, M.

    2007-01-01

    More than twenty-five years after the advent of DNA markers, marker-assisted selection (MAS) has become a routine component of some private maize breeding programmes. Line conversion has been one of the most productive applications of MAS in maize breeding, reducing time to market and resulting in countless numbers of commercial products. Recently, applications of MAS for forward breeding have been shown to increase significantly the rate of genetic gain when compared with conventional breeding. Costs associated with MAS are still very high. Further improvements in marker technologies, data handling and analysis, phenotyping and nursery operations are needed to realize the full benefits of MAS for private maize breeding programmes and to allow the transfer of proven approaches and protocols to public breeding programmes in developing countries. (author)

  6. Barriers and Potential Improvements for Needle and Syringe Exchange Programs (NSPs in China: A Qualitative Study from Perspectives of Both Health and Public Security Sectors.

    Directory of Open Access Journals (Sweden)

    Fung Kuen Koo

    Full Text Available This study explores the acceptability, the barriers to the implementation of needle and syringe exchange programs (NSPs and the potential improvement strategies in China from the perspectives of governmental health and public security officials. Purposive sampling was used for recruitment of participants who had been involved in NSPs implementation. Semi-Structured individual interviews were conducted in Mandarin to address three aspects of NSPs: (1 participants' attitudes towards NSPs, (2 participants' opinions on the effectiveness and barriers of NSPs, and (3 suggestions for improving the program. Content analysis was used to analyse the translated interview data. A total of 68 participants from 12 Hunan counties were interviewed (34 from each of the Bureau of Health and the Narcotic Division. Both groups recognised the importance and effectiveness of NSPs in HIV prevention, but public security officials regarded NSPs as a temporary intervention in place of punitive measures. Most health officials (32/34 regarded the main barriers to its implementation as administrative and structural, whereas participants from Narcotics Division (n=24 questioned the legitimacy of NSPs and concerned about the poor management of drug users' risk behaviours. Close cooperation between the health and public security sectors, engagement of the drug user community and an enabling policy environment were reportedly to be critical for potential improvements of NSPs in China. Misconceptions about NSPs encourage drug users' addictive behaviour, and an unclear leadership and insufficient support de-motivate the participants from the Bureau of Health and the Narcotics Division to actively support the program implementation.

  7. Arsenic and Chromium in Canned and Non-Canned Beverages in Nigeria: A Potential Public Health Concern

    OpenAIRE

    Maduabuchi, J.-M. U.; Adigba, E. O.; Nzegwu, C. N.; Oragwu, C. I.; Okonkwo, I. P.; Orisakwe, Orish E.

    2007-01-01

    Numerous studies have described environmental exposure of humans to heavy metals in African populations. Little is known about the exposure to heavy metal toxins from processed or unprocessed foods consumed in Africa, and no data exists on the food concentrations of arsenic and chromium, which are potential carcinogens and systemic toxicants. This study determined the concentrations of arsenic and chromium in beverages and fruit drinks commonly sold in Nigeria. Fifty samples of commonly consu...

  8. Genetic Alterations in Pesticide Exposed Bolivian Farmers

    DEFF Research Database (Denmark)

    Jørs, Erik; González, Ana Rosa; Ascarrunz, Maria Eugenia

    2007-01-01

    : Questionnaires were applied and blood tests taken from 81 volunteers from La Paz County, of whom 48 were pesticide exposed farmers and 33 non-exposed controls. Sixty males and 21 females participated with a mean age of 37.3 years (range 17-76). Data of exposure and possible genetic damage were collected...... and evaluated by well known statistical methods, controlling for relevant confounders. To measure genetic damage chromosomal aberrations and the comet assay analysis were performed. Results: Pesticide exposed farmers had a higher degree of genetic damage compared to the control group. The number of chromosomal......, probably related to exposure to pesticides. Due to the potentially negative long term health effects of genetic damage on reproduction and the development of cancer, preventive measures are recommended. Effective control with imports and sales, banning of the most toxic pesticides, education...

  9. The potential of ecological theory for building an integrated framework to develop the public health contribution of health visiting.

    Science.gov (United States)

    Bryans, Alison; Cornish, Flora; McIntosh, Jean

    2009-11-01

    In line with recent UK and Scottish policy imperatives, there is increasing pressure for the health visiting service to assume an enhanced role in improving public health. Although health visiting has so far maintained its unique position as a primarily preventive service within the UK health service, its distinctive contribution now appears under threat. The continuing absence of a comprehensive and integrated conceptual basis for practice has a negative impact on the profession's ability to respond to current challenges. Establishing an integrative framework to conceptualise health visiting practice would enable more sensitive, focused and appropriate research, education and evaluation in relation to practice. Work in this area could thus usefully contribute to the future development of the service at a difficult time. Our paper aims to make such a contribution. In support of our conceptual aims, we draw on a study of health visiting practice undertaken within a large conurbation in central Scotland. The study used a mixed method, collaborative approach involving 12 audio-recorded and observed health visitor-client interactions, semi-structured interviews with the 12 HVs and 12 clients, examination of related documentation and workshops with the HV participants. We critically consider prevalent models of health visiting practice and describe the more integrative conceptual approach provided by Bronfenbrenner's ecological, 'person-in-context' framework. The paper subsequently explores relationships between this framework and understandings of need demonstrated by health visitors who participated in our study. Current policy emphasises the need to focus on public health and social inclusion in order to improve health. However, if this policy is to be translated into practice, we must develop a more adequate understanding of how practitioners work effectively with families and individuals in a sensitive and context-specific manner. Bronfenbrenner's framework appears

  10. Invasive forms of canine endoparasites as a potential threat to public health - A review and own studies.

    Science.gov (United States)

    Felsmann, Mirosława; Michalski, Mirosław; Felsmann, Mariusz; Sokół, Rajmund; Szarek, Józef; Strzyżewska-Worotyńska, Emilia

    2017-05-11

    [b]Abstract [/b] Dogs serve as the vectors of serious zoonotic parasitic diseases. In the month of May 2012 - 2014, 339 dog faeces samples from seven public sites in Chełmno, a town in northern Poland, were collected and examined to determine the gastrointestinal parasite fauna of dogs. Each faecal sample was dissected with a needle, checked for tapeworm segments and examined for parasite eggs and oocysts using the flotation and decantation method and a modified Baermann technique. Differences were observed in the degree of parasite species occurrence. The most dominant were [i]Toxocara canis[/i] and Ancylostomatidae. The detected species included: [i]T. canis [/i]and [i]Toxascaris leonina[/i] eggs (23.4% and 10.2%, respectively), as well as eggs from the[i] Ancylostomatidae[/i] family (16.2%),[i] Trichuris vulpis [/i]eggs (6.6%), [i]Taenia[/i] type eggs (4.6%),[i] Dipylidium caninum[/i] (5.2%) and [i]Cystoisospora [/i](Isospora) spp. oocysts (10.9%).

  11. District decision-making for health in low-income settings: a case study of the potential of public and private sector data in India and Ethiopia.

    Science.gov (United States)

    Bhattacharyya, Sanghita; Berhanu, Della; Taddesse, Nolawi; Srivastava, Aradhana; Wickremasinghe, Deepthi; Schellenberg, Joanna; Iqbal Avan, Bilal

    2016-09-01

    Many low- and middle-income countries have pluralistic health systems where private for-profit and not-for-profit sectors complement the public sector: data shared across sectors can provide information for local decision-making. The third article in a series of four on district decision-making for health in low-income settings, this study shows the untapped potential of existing data through documenting the nature and type of data collected by the public and private health systems, data flow and sharing, use and inter-sectoral linkages in India and Ethiopia. In two districts in each country, semi-structured interviews were conducted with administrators and data managers to understand the type of data maintained and linkages with other sectors in terms of data sharing, flow and use. We created a database of all data elements maintained at district level, categorized by form and according to the six World Health Organization health system blocks. We used content analysis to capture the type of data available for different health system levels. Data flow in the public health sectors of both counties is sequential, formal and systematic. Although multiple sources of data exist outside the public health system, there is little formal sharing of data between sectors. Though not fully operational, Ethiopia has better developed formal structures for data sharing than India. In the private and public sectors, health data in both countries are collected in all six health system categories, with greatest focus on service delivery data and limited focus on supplies, health workforce, governance and contextual information. In the Indian private sector, there is a better balance than in the public sector of data across the six categories. In both India and Ethiopia the majority of data collected relate to maternal and child health. Both countries have huge potential for increased use of health data to guide district decision-making. © The Author 2016. Published by Oxford

  12. HIV pre-exposure prophylaxis: Exploring the potential for expanding the role of pharmacists in public health.

    Science.gov (United States)

    Okoro, Olihe; Hillman, Lisa

    2018-05-19

    The study objectives were to a) assess knowledge and experience; b) describe perceptions and attitudes; and c) identify training needs of community-based pharmacists regarding HIV pre-exposure prophylaxis (PrEP). This was a cross-sectional survey study. The survey was administered online to pharmacists practicing in a community setting in the state of Minnesota. Measures included knowledge of and experience with HIV PrEP, perceptions and attitudes towards pharmacists' involvement, and HIV PrEP-specific training needs for pharmacists. With a survey response rate of approximately 13% (n = 347), most respondents (76.4%) agreed that HIV PrEP can be beneficial in high-risk populations. Forty-six percent of respondents were not aware of U.S. Food and Drug Administration approval of emtricitabine and tenofovir disoproxil fumarate for PrEP. Most respondents (71.1%) were "not at all familiar" with Centers for Disease Control and Prevention guidelines for PrEP. Twenty-one percent of respondents had sufficient knowledge to counsel patients on PrEP. Experience with counseling on PrEP (21.8%), having dispensed PrEP in the last 2 years (33.1%), fewer years in practice (≤10 years), location of practice site (urban or suburban), and having received HIV continuing education in the last 2 years (33.0%) were associated with more knowledge of HIV PrEP. Top concerns with counseling were knowledge about the medication and behavior modification. The most frequently indicated primary concerns with implementing PrEP initiatives were identifying appropriate candidates and patient adherence. As pharmacists' roles continue to expand, relevant content in pharmacy education and requisite training (including continuing education) are critical to addressing knowledge gaps and competencies that will enable pharmacists engage more effectively in public health efforts such as HIV prevention. Published by Elsevier Inc.

  13. Fibrosis biomarkers in workers exposed to MWCNTs

    International Nuclear Information System (INIS)

    Fatkhutdinova, Liliya M.; Khaliullin, Timur O.; Vasil'yeva, Olga L.; Zalyalov, Ramil R.; Mustafin, Ilshat G.; Kisin, Elena R.; Birch, M. Eileen; Yanamala, Naveena; Shvedova, Anna A.

    2016-01-01

    Multi-walled carbon nanotubes (MWCNT) with their unique physico-chemical properties offer numerous technological advantages and are projected to drive the next generation of manufacturing growth. As MWCNT have already found utility in different industries including construction, engineering, energy production, space exploration and biomedicine, large quantities of MWCNT may reach the environment and inadvertently lead to human exposure. This necessitates the urgent assessment of their potential health effects in humans. The current study was carried out at NanotechCenter Ltd. Enterprise (Tambov, Russia) where large-scale manufacturing of MWCNT along with relatively high occupational exposure levels was reported. The goal of this small cross-sectional study was to evaluate potential biomarkers during occupational exposure to MWCNT. All air samples were collected at the workplaces from both specific areas and personal breathing zones using filter-based devices to quantitate elemental carbon and perform particle analysis by TEM. Biological fluids of nasal lavage, induced sputum and blood serum were obtained from MWCNT-exposed and non-exposed workers for assessment of inflammatory and fibrotic markers. It was found that exposure to MWCNTs caused significant increase in IL-1β, IL6, TNF-α, inflammatory cytokines and KL-6, a serological biomarker for interstitial lung disease in collected sputum samples. Moreover, the level of TGF-β1 was increased in serum obtained from young exposed workers. Overall, the results from this study revealed accumulation of inflammatory and fibrotic biomarkers in biofluids of workers manufacturing MWCNTs. Therefore, the biomarkers analyzed should be considered for the assessment of health effects of occupational exposure to MWCNT in cross-sectional epidemiological studies. - Highlights: • The effects of MWCNT exposure in humans remain unclear. • We found increased KL-6/TGF-β levels in the biofluids of MWCNT-exposed workers.

  14. Fibrosis biomarkers in workers exposed to MWCNTs

    Energy Technology Data Exchange (ETDEWEB)

    Fatkhutdinova, Liliya M., E-mail: liliya.fatkhutdinova@gmail.com [Kazan State Medical University, ul. Butlerova 49, Kazan 420012 (Russian Federation); Khaliullin, Timur O., E-mail: Khaliullin.40k@gmail.com [Kazan State Medical University, ul. Butlerova 49, Kazan 420012 (Russian Federation); Department of Physiology & Pharmacology, WVU, Morgantown, WV (United States); Vasil' yeva, Olga L., E-mail: volgaleon@gmail.com [Kazan State Medical University, ul. Butlerova 49, Kazan 420012 (Russian Federation); Zalyalov, Ramil R., E-mail: zalyalov.ramil@gmail.com [Kazan State Medical University, ul. Butlerova 49, Kazan 420012 (Russian Federation); Mustafin, Ilshat G., E-mail: ilshat64@mail.ru [Kazan State Medical University, ul. Butlerova 49, Kazan 420012 (Russian Federation); Kisin, Elena R., E-mail: edk8@cdc.gov [National Institute for Occupational Safety and Health, Morgantown, WV (United States); Birch, M. Eileen, E-mail: mib2@cdc.gov [National Institute for Occupational Safety and Health, Cincinnati, OH (United States); Yanamala, Naveena, E-mail: wqu1@cdc.gov [National Institute for Occupational Safety and Health, Morgantown, WV (United States); Shvedova, Anna A., E-mail: ats1@cdc.gov [National Institute for Occupational Safety and Health, Morgantown, WV (United States); Department of Physiology & Pharmacology, WVU, Morgantown, WV (United States)

    2016-05-15

    Multi-walled carbon nanotubes (MWCNT) with their unique physico-chemical properties offer numerous technological advantages and are projected to drive the next generation of manufacturing growth. As MWCNT have already found utility in different industries including construction, engineering, energy production, space exploration and biomedicine, large quantities of MWCNT may reach the environment and inadvertently lead to human exposure. This necessitates the urgent assessment of their potential health effects in humans. The current study was carried out at NanotechCenter Ltd. Enterprise (Tambov, Russia) where large-scale manufacturing of MWCNT along with relatively high occupational exposure levels was reported. The goal of this small cross-sectional study was to evaluate potential biomarkers during occupational exposure to MWCNT. All air samples were collected at the workplaces from both specific areas and personal breathing zones using filter-based devices to quantitate elemental carbon and perform particle analysis by TEM. Biological fluids of nasal lavage, induced sputum and blood serum were obtained from MWCNT-exposed and non-exposed workers for assessment of inflammatory and fibrotic markers. It was found that exposure to MWCNTs caused significant increase in IL-1β, IL6, TNF-α, inflammatory cytokines and KL-6, a serological biomarker for interstitial lung disease in collected sputum samples. Moreover, the level of TGF-β1 was increased in serum obtained from young exposed workers. Overall, the results from this study revealed accumulation of inflammatory and fibrotic biomarkers in biofluids of workers manufacturing MWCNTs. Therefore, the biomarkers analyzed should be considered for the assessment of health effects of occupational exposure to MWCNT in cross-sectional epidemiological studies. - Highlights: • The effects of MWCNT exposure in humans remain unclear. • We found increased KL-6/TGF-β levels in the biofluids of MWCNT-exposed workers.

  15. Exploiting the potential of intranet for managing drug spectrum a web base publication in a Tertiary Care Hospital in Mumbai

    Directory of Open Access Journals (Sweden)

    Yashashri Chandrakant Shetty

    2015-01-01

    Full Text Available Objective: The study surveyed the availability of the intranet in campus and also the knowledge related to drug spectrum an intranet publication. Materials and Methods: Institutional ethics committee permission was obtained. Verbal consent was taken from the faculty and resident doctors of departments where all the facilities were available. Universal sampling method was used for recruitment. Pre-validated questionnaires were given to approximately 100 faculty and 500 resident doctors in the year 2012-2013. The questionnaire contained 15 items. Content analysis was done. The study questionnaire focused on a survey to obtain participants feedback on the use of the intranet and to evaluate the use of intranet as a source of knowledge. It also dealt on the relevance of the drug spectrum in the context of their subject. The responses were taken after giving the participants sufficient time. Data was entered into an Excel 2003 spread sheet and analyzed by using descriptive statistics. Results: The total number of respondents who participated in our study was 134 including faculty and residents from various departments. A total of 117 (89.66% respondents stated that their departments have access to the internet. Departments having access to intranet was 103 (76.29%. 67 (49.62% respondents have accessed. 67 (49.62% did not have the time to visit intranet site whereas 67 (49.62% have not accessed intranet. 89 (65.92% respondents were not aware of the drug spectrum. 101 (74.81% respondents felt that drug spectrum is a useful activity on intranet. 45 (33.33% knew about the intranet periodical drug spectrum, but most of the respondents (33.33% explained the meaning of the word drug spectrum according to their understanding, but never knew about the online intranet journal drug spectrum. Conclusion: The study found that the intranet is available in the campus, but it is not being utilized. The awareness and knowledge regarding drug spectrum is lacking, but

  16. Public health impact of global heating due to climate change: potential effects on chronic non-communicable diseases.

    Science.gov (United States)

    Kjellstrom, Tord; Butler, Ainslie J; Lucas, Robyn M; Bonita, Ruth

    2010-04-01

    Several categories of ill health important at the global level are likely to be affected by climate change. To date the focus of this association has been on communicable diseases and injuries. This paper briefly analyzes potential impacts of global climate change on chronic non-communicable diseases (NCDs). We reviewed the limited available evidence of the relationships between climate exposure and chronic and NCDs. We further reviewed likely mechanisms and pathways for climatic influences on chronic disease occurrence and impacts on pre-existing chronic diseases. There are negative impacts of climatic factors and climate change on some physiological functions and on cardio-vascular and kidney diseases. Chronic disease risks are likely to increase with climate change and related increase in air pollution, malnutrition, and extreme weather events. There are substantial research gaps in this arena. The health sector has a major role in facilitating further research and monitoring the health impacts of global climate change. Such work will also contribute to global efforts for the prevention and control of chronic NCDs in our ageing and urbanizing global population.

  17. Potential barriers to the application of multi-factor portfolio analysis in public hospitals: evidence from a pilot study in the Netherlands.

    Science.gov (United States)

    Pavlova, Milena; Tsiachristas, Apostolos; Vermaeten, Gerhard; Groot, Wim

    2009-01-01

    Portfolio analysis is a business management tool that can assist health care managers to develop new organizational strategies. The application of portfolio analysis to US hospital settings has been frequently reported. In Europe however, the application of this technique has received little attention, especially concerning public hospitals. Therefore, this paper examines the peculiarities of portfolio analysis and its applicability to the strategic management of European public hospitals. The analysis is based on a pilot application of a multi-factor portfolio analysis in a Dutch university hospital. The nature of portfolio analysis and the steps in a multi-factor portfolio analysis are reviewed along with the characteristics of the research setting. Based on these data, a multi-factor portfolio model is developed and operationalized. The portfolio model is applied in a pilot investigation to analyze the market attractiveness and hospital strengths with regard to the provision of three orthopedic services: knee surgery, hip surgery, and arthroscopy. The pilot portfolio analysis is discussed to draw conclusions about potential barriers to the overall adoption of portfolio analysis in the management of a public hospital. Copyright (c) 2008 John Wiley & Sons, Ltd.

  18. Landfills in Jiangsu province, China, and potential threats for public health: Leachate appraisal and spatial analysis using geographic information system and remote sensing

    International Nuclear Information System (INIS)

    Yang Kun; Zhou Xiaonong; Yan Weian; Hang Derong; Steinmann, Peter

    2008-01-01

    Waste disposal is of growing environmental and public health concern in China where landfilling is the predominant method of disposal. The assessment of potential health hazards posed by existing landfills requires sound information, and processing of a significant amount of spatial data. Geographical information system (GIS) and remote sensing (RS) are valuable tools for assessing health impacts due to landfills. The aims of this study were: (i) to analyze the leachate and gas emissions from landfills used for domestic waste disposal in a metropolitan area of Jiangsu province, China, (ii) to investigate remotely-sensed environmental features in close proximity to landfills, and (iii) to evaluate the compliance of their location and leachate quality with the relevant national regulations. We randomly selected five landfills in the metropolitan areas of Wuxi and Suzhou city, Jiangsu province, established a GIS database and examined whether data were in compliance with national environmental and public health regulations. The leachates of the sampled landfills contained heavy metals (Pb, As, Cr 6+ and Hg) and organic compounds in concentrations considered harmful to human health. Measured methane concentrations on landfill surfaces were low. Spatial analysis of the location of landfills with regard to distance from major water bodies, sensible infrastructure and environmental conditions according to current national legislation resulted in the rejection of four of the five sites as inappropriate for landfills. Our results call for rigorous evaluation of the spatial location of landfills in China that must take into consideration environmental and public health criteria

  19. Arsenic and Chromium in Canned and Non-Canned Beverages in Nigeria: A Potential Public Health Concern

    Directory of Open Access Journals (Sweden)

    Orish E. Orisakwe

    2007-03-01

    Full Text Available Numerous studies have described environmental exposure of humans to heavy metals in African populations. Little is known about the exposure to heavy metal toxins from processed or unprocessed foods consumed in Africa, and no data exists on the food concentrations of arsenic and chromium, which are potential carcinogens and systemic toxicants. This study determined the concentrations of arsenic and chromium in beverages and fruit drinks commonly sold in Nigeria. Fifty samples of commonly consumed canned and non-canned beverages (imported and locally manufactured purchased in Nigeria were digested in nitric acid and analyzed by atomic absorption spectrophotometry (AAS. 33.3% of the canned beverages had arsenic levels that exceeded the maximum contaminant level (MCL of 0.01 mg/L set by U.S. EPA while 55.2% of non-canned beverages had their arsenic levels exceeding the MCL. The arsenic concentrations ranged from 0.003 to 0.161 mg/L for the canned and 0.002 to 0.261 mg/l for the non-canned beverages. Whereas 68.9% of the non-canned beverages showed chromium levels that exceeded the US EPA’s MCL of 0.10 mg/L, 76.2% of the canned beverages had chromium levels that were greater than the MCL. The concentration range of total chromium in the canned beverages was 0.04 to 0.59 mg/L and 0.01 to 0.55 mg/L for the non-canned beverages. The sources of arsenic and chromium in the commercially available beverages are unclear and merit further investigation. This preliminary study highlights the need to study the toxicological implications of chronic low-level exposure to heavy metals from African markets.

  20. Unusual presentation of necrotizing fasciitis in an HIV exposed infant

    African Journals Online (AJOL)

    ... presentation of NF, in this instance, it presented on the scalp, in an HIV exposed neonate. It also stressed the importance prompt diagnosis of all skin lesions in HIV exposed neonates, and the role of early diagnosis and aggressive multi disciplinary team management in salvaging NF which is a potentially fatal condition.

  1. La imprecisión del lenguaje legislativo, expuesta en el artículo 18 LRJSP | The Imprecision Of Statutory Language, Exposed In Section 18 Of The Spanish Act On Legal Status Of The Public Sector (LRJSP

    Directory of Open Access Journals (Sweden)

    Joaquín Rodríguez-Toubes Muñiz

    2017-12-01

    Full Text Available Resumen: La imprecisión lingüística es una de las razones principales por las que es necesario interpretar las disposiciones legales, junto a la percepción de incongruencia entre su significado y la razón práctica que las explica o justifica. Son causas de imprecisión del lenguaje legislativo la vaguedad, la ambigüedad semántica, la ambigüedad pragmática y algunas otras, como la redundancia, la repetición, la infraespecificación, la inconsistencia y las anomalías. Todas ellas están presentes en el artículo 18 de la Ley 40/2015, de 1 de octubre, de Régimen Jurídico del Sector Público. El trabajo analiza la imprecisión lingüística de las leyes con una clasificación de problemas sistemática y tomando este artículo como caso de estudio. Abstract: Linguistic imprecision is one of the main reasons why interpreting statutes is necessary, besides the perception of incongruence between their meaning and the practical reason that explains or justifies them. Causes or imprecision of statutory language are vagueness, semantic ambiguity, pragmatic ambiguity and some others, such as redundancy, repetition, infraspecification, inconsistence and anomalies. All of them are present in section 18 of the Spanish Law 40/2015, of 1 October, of Legal Regime of the Public Sector [Ley de Régimen Jurídico del Sector Público]. The paper analyses the linguistic imprecision of statutes with a systematic and comprehensive classification of problems, and taking that section 18 as a study case.

  2. Prefrontal white matter pathology in air pollution exposed Mexico City young urbanites and their potential impact on neurovascular unit dysfunction and the development of Alzheimer's disease

    International Nuclear Information System (INIS)

    Calderón-Garcidueñas, Lilian; Reynoso-Robles, Rafael; Vargas- Martínez, Javier; Gómez-Maqueo-Chew, Aline; Pérez-Guillé, Beatriz; Mukherjee, Partha S.; Torres-Jardón, Ricardo; Perry, George; Gónzalez-Maciel, Angélica

    2016-01-01

    Millions of urban children are chronically exposed to high concentrations of air pollutants, i.e., fine particulate matter (PM 2.5 ) and ozone, associated with increased risk for Alzheimer's disease. Compared with children living with clear air those in Mexico City (MC) exhibit systemic, brain and intrathecal inflammation, low CSF Aβ 42, breakdown of the BBB, attention and short-term memory deficits, prefrontal white matter hyperintensities, damage to epithelial and endothelial barriers, tight junction and neural autoantibodies, and Alzheimer and Parkinson's hallmarks. The prefrontal white matter is a target of air pollution. We examined by light and electron microscopy the prefrontal white matter of MC dogs (n: 15, age 3.17±0.74 years), children and teens (n: 34, age: 12.64±4.2 years) versus controls. Major findings in MC residents included leaking capillaries and small arterioles with extravascular lipids and erythrocytes, lipofuscin in pericytes, smooth muscle and endothelial cells (EC), thickening of cerebrovascular basement membranes with small deposits of amyloid, patchy absence of the perivascular glial sheet, enlarged Virchow–Robin spaces and nanosize particles (20–48 nm) in EC, basement membranes, axons and dendrites. Tight junctions, a key component of the neurovascular unit (NVU) were abnormal in MC versus control dogs (χ 2 <0.0001), and white matter perivascular damage was significantly worse in MC dogs (p=0.002). The integrity of the NVU, an interactive network of vascular, glial and neuronal cells is compromised in MC young residents. Characterizing the early NVU damage and identifying biomarkers of neurovascular dysfunction may provide a fresh insight into Alzheimer pathogenesis and open opportunities for pediatric neuroprotection. - Highlights: • The prefrontal white matter is a target of air pollution. • Tight junctions, key neurovascular unit elements, are abnormal in young urbanites. • Identifying neurovascular dysfunction

  3. Research into Mercury Exposure and Health Education in Subsistence Fish-Eating Communities of the Amazon Basin: Potential Effects on Public Health Policy

    Directory of Open Access Journals (Sweden)

    José G. Dórea

    2010-09-01

    Full Text Available The neurotoxic effects of fish-methylmercury (meHg consumed regularly are considered hazardous to fetuses and newborn infants; as a result fish consumption advisories are an important asset to control meHg exposure in affluent societies. These concerns are now part of health promotion programs for Amazon subsistence villagers. While urban dwellers in affluent societies can choose an alternative nutritious diet, traditional and subsistence communities are caught up in controversial issues and lifestyle changes with unintended health consequences. Traditional fish-eating populations of industrialized and non-industrialized regions may be exposed to different neurotoxic substances: man-made pollutants and environmentally occurring meHg. Additionally, in non-industrialized countries, pregnant women and infants are still being immunized with thimerosal-containing vaccines (TCVs which degrade to ethylmercury (etHg. Therefore, the complexity involving fish-meHg associated with wild-fish choices and Hg exposure derived from TCVs is difficult to disentangle and evaluate: are villagers able to distinguish exposure to differently hazardous chemical forms of Hg (inorganic, fish-meHg, and injected etHg? Is it possible that instead of helping to prevent a plausible (unperceived fish-meHg associated neurocognitive delay we may inadvertently arouse panic surrounding Hg exposure and disrupt subsistence fish-eating habits (necessary for survival and life-saving vaccination programs (required by public health authorities? These questions characterize the incompleteness of information related on the various chemical forms of Hg exposure and the need to convey messages that do not disrupt nutritional balance and disease prevention policies directed at Amazonian subsistence communities.

  4. Prefrontal white matter pathology in air pollution exposed Mexico City young urbanites and their potential impact on neurovascular unit dysfunction and the development of Alzheimer's disease

    Energy Technology Data Exchange (ETDEWEB)

    Calderón-Garcidueñas, Lilian, E-mail: lilian.calderon-garciduenas@umontana.edu [The University of Montana, Missoula, MT 59812 (United States); Universidad del Valle de México, Mexico City 04850, México (Mexico); Reynoso-Robles, Rafael [Instituto Nacional de Pediatría, Mexico City 04530 México (Mexico); Vargas- Martínez, Javier [Universidad del Valle de México, Mexico City 04850, México (Mexico); Gómez-Maqueo-Chew, Aline [Universidad del Valle de México, Hermosillo, Sonora 83299, México (Mexico); Pérez-Guillé, Beatriz [Instituto Nacional de Pediatría, Mexico City 04530 México (Mexico); Mukherjee, Partha S. [Mathematics Department, Boise State University, Boise, ID (United States); Torres-Jardón, Ricardo [Centro de Ciencias de la Atmósfera, Universidad Nacional Autónoma de México, Mexico City 04310, México (Mexico); Perry, George [College of Sciences, University of Texas at San Antonio, San Antonio, TX (United States); Gónzalez-Maciel, Angélica [Instituto Nacional de Pediatría, Mexico City 04530 México (Mexico)

    2016-04-15

    Millions of urban children are chronically exposed to high concentrations of air pollutants, i.e., fine particulate matter (PM{sub 2.5}) and ozone, associated with increased risk for Alzheimer's disease. Compared with children living with clear air those in Mexico City (MC) exhibit systemic, brain and intrathecal inflammation, low CSF Aβ{sub 42,} breakdown of the BBB, attention and short-term memory deficits, prefrontal white matter hyperintensities, damage to epithelial and endothelial barriers, tight junction and neural autoantibodies, and Alzheimer and Parkinson's hallmarks. The prefrontal white matter is a target of air pollution. We examined by light and electron microscopy the prefrontal white matter of MC dogs (n: 15, age 3.17±0.74 years), children and teens (n: 34, age: 12.64±4.2 years) versus controls. Major findings in MC residents included leaking capillaries and small arterioles with extravascular lipids and erythrocytes, lipofuscin in pericytes, smooth muscle and endothelial cells (EC), thickening of cerebrovascular basement membranes with small deposits of amyloid, patchy absence of the perivascular glial sheet, enlarged Virchow–Robin spaces and nanosize particles (20–48 nm) in EC, basement membranes, axons and dendrites. Tight junctions, a key component of the neurovascular unit (NVU) were abnormal in MC versus control dogs (χ{sup 2}<0.0001), and white matter perivascular damage was significantly worse in MC dogs (p=0.002). The integrity of the NVU, an interactive network of vascular, glial and neuronal cells is compromised in MC young residents. Characterizing the early NVU damage and identifying biomarkers of neurovascular dysfunction may provide a fresh insight into Alzheimer pathogenesis and open opportunities for pediatric neuroprotection. - Highlights: • The prefrontal white matter is a target of air pollution. • Tight junctions, key neurovascular unit elements, are abnormal in young urbanites. • Identifying

  5. Assessing the potential effectiveness of food and beverage taxes and subsidies for improving public health: a systematic review of prices, demand and body weight outcomes.

    Science.gov (United States)

    Powell, L M; Chriqui, J F; Khan, T; Wada, R; Chaloupka, F J

    2013-02-01

    Taxes and subsidies are increasingly being considered as potential policy instruments to incentivize consumers to improve their food and beverage consumption patterns and related health outcomes. This study provided a systematic review of recent U.S. studies on the price elasticity of demand for sugar-sweetened beverages (SSBs), fast food, and fruits and vegetables, as well as the direct associations of prices/taxes with body weight outcomes. Based on the recent literature, the price elasticity of demand for SSBs, fast food, fruits and vegetables was estimated to be -1.21, -0.52, -0.49 and -0.48, respectively. The studies that linked soda taxes to weight outcomes showed minimal impacts on weight; however, they were based on existing state-level sales taxes that were relatively low. Higher fast-food prices were associated with lower weight outcomes particularly among adolescents, suggesting that raising prices would potentially impact weight outcomes. Lower fruit and vegetable prices were generally found to be associated with lower body weight outcomes among both low-income children and adults, suggesting that subsidies that would reduce the cost of fruits and vegetables for lower-socioeconomic populations may be effective in reducing obesity. Pricing instruments should continue to be considered and evaluated as potential policy instruments to address public health risks. © 2012 The Authors. obesity reviews © 2012 International Association for the Study of Obesity.

  6. Assessing the Potential Effectiveness of Food and Beverage Taxes and Subsidies for Improving Public Health: A Systematic Review of Prices, Demand and Body Weight Outcomes

    Science.gov (United States)

    Powell, Lisa M.; Chriqui, Jamie F.; Khan, Tamkeen; Wada, Roy; Chaloupka, Frank J.

    2012-01-01

    Taxes and subsidies are increasingly being considered as potential policy instruments to incentivize consumers to improve their food and beverage consumption patterns and related health outcomes. This study provided a systematic review of recent U.S. studies on the price elasticity of demand for sugar-sweetened beverages (SSBs), fast food and fruits and vegetables as well as the direct associations of prices/taxes with body weight outcomes. Based on the recent literature, the price elasticity of demand for SSBs, fast food, fruits and vegetables was estimated to be −1.21, −0.52, −0.49 and −0.48, respectively. The studies that linked soda taxes to weight outcomes showed minimal impacts on weight; however, they were based on existing state-level sales taxes that were relatively low. Higher fast-food prices were associated with lower weight outcomes particularly among adolescents suggesting that raising prices would potentially impact weight outcomes. Lower fruit and vegetable prices were generally found to be associated with lower body weight outcomes among both low-income children and adults suggesting that subsidies that would reduce the cost of fruits and vegetables for lower-socioeconomic populations may be effective in reducing obesity. Pricing instruments should continue to be considered and evaluated as potential policy instruments to address public health risks. PMID:23174017

  7. Estimation of the contribution of neutrons to the equivalent dose for personnel occupationally exposed and public in medical facilities: X-ray with energy equal or greater than 10MV; Estimacion de la contribucion por neutrones a la dosis equivalente para personal ocupacionalmente expuesto y publico en instalaciones de uso medico: rayos X de energia igual y/o superior a 10MV

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez, Alfonso Mayer; Jimenez, Roberto Ortega; Sanchez, Mario A. Reyes, E-mail: amgesfm@hotmail.com, E-mail: rojimenez@cnsns.gob.mx [Comision Nacional de Seguridad Nuclear y Salvaguardias (CNSNS), Mexico, D.F. (Mexico); Moranchel y Mejia, Mario, E-mail: mmoranchel@ipn.mx [Instituto Politecnico Nacional (ESFM/IPN), Mexico, D.F. (Mexico). Escuela Superior de Fisica y Matematicas. Departamento de lngenieria Nuclear

    2013-07-01

    In Mexico the use of electron accelerators for treating cancerous tumors had grown enormously in the last decade. When the treatments are carried out with X-ray beam energy below 10 MV the design of the shielding of the radioactive facility is determined by analyzing the interaction of X-rays, which have a direct impact and dispersion, with materials of the facility. However, when it makes use of X-ray beam energy equal to or greater than 10 MV the neutrons presence is imminent due to their generation by the interaction of the primary beam X-ray with materials head of the accelerator and of the table of treatment, mainly. In these cases, the design and calculation of shielding considers the generation of high-energy neutrons which contribute the equivalent dose that public and Occupationally Staff Exposed (POE) will receive in the areas surrounding the facility radioactive. However, very few measurements have been performed to determine the actual contribution to the neutron dose equivalent received by POE and public during working hours. This paper presents an estimate of the actual contribution of the neutron dose equivalent received by public and POE facilities in various radioactive medical use, considering many factors. To this end, measurements were made of the equivalent dose by using a neutron monitor in areas surrounding different radioactive installations (of Mexico) which used electron accelerators medical use during treatment with X-ray beam energy equal to or greater than 10 MV. The results are presented after a statistical analysis of a wide range of measures in order to estimate more reliability real contribution of the neutron dose equivalent for POE and the public. (author)

  8. The Challenges of Projecting the Public Health Impacts of Marijuana Legalization in Canada; Comment on “Legalizing and Regulating Marijuana in Canada: Review of Potential Economic, Social, and Health Impacts”

    Directory of Open Access Journals (Sweden)

    Stephanie Lake

    2017-05-01

    Full Text Available A recent editorial in this journal provides a summary of key economic, social, and public health considerations of the forthcoming legislation to legalize, regulate, and restrict access to marijuana in Canada. As our government plans to implement an evidence-based public health framework for marijuana legalization, we reflect and expand on recent discussions of the public health implications of marijuana legalization, and offer additional points of consideration. We select two commonly cited public concerns of marijuana legalization – adolescent usage and impaired driving – and discuss how the underdeveloped and equivocal body of scientific literature surrounding these issues limits the ability to predict the effects of legalization. Finally, we discuss the potential for some potential public health benefits of marijuana legalization – specifically the potential for marijuana to be used as a substitute to opioids and other risky substance use – that have to date not received adequate attention.

  9. [Organization of public oral health services for early diagnosis of potentially malignant disorders in the state of Rio de Janeiro, Brazil].

    Science.gov (United States)

    Casotti, Elisete; Monteiro, Ana Beatriz Fonseca; Castro Filho, Evelyn Lima de; Santos, Manuella Pires Dos

    2016-05-01

    This is a study of the organization of public health services in the state of Rio de Janeiro concerning the diagnosis of potentially malignant disorders. Secondary data from the database of the first phase of the Program for Enhancement for Access to and Quality of Primary Care were used. The implementation of actions at different levels for cancer prevention, the availability of diagnostic support services and the organization of the care network were assessed. The results show that only 58.8% of oral health teams record and monitor suspect cases; that only 47.1% reported having preferential channels for referring patients and there is great variation in waiting times to confirm the diagnosis. Local managerial and regional support actions can improve the organization of the care network for oral cancer prevention in the state.

  10. The Potential of Mobile Apps for Improving Asthma Self-Management: A Review of Publicly Available and Well-Adopted Asthma Apps

    Science.gov (United States)

    Tinschert, Peter; Jakob, Robert; Barata, Filipe; Kramer, Jan-Niklas

    2017-01-01

    Background Effective disease self-management lowers asthma’s burden of disease for both individual patients and health care systems. In principle, mobile health (mHealth) apps could enable effective asthma self-management interventions that improve a patient’s quality of life while simultaneously reducing the overall treatment costs for health care systems. However, prior reviews in this field have found that mHealth apps for asthma lack clinical evaluation and are often not based on medical guidelines. Yet, beyond the missing evidence for clinical efficacy, little is known about the potential apps might have for improving asthma self-management. Objective The aim of this study was to assess the potential of publicly available and well-adopted mHealth apps for improving asthma self-management. Methods The Apple App store and Google Play store were systematically searched for asthma apps. In total, 523 apps were identified, of which 38 apps matched the selection criteria to be included in the review. Four requirements of app potential were investigated: app functions, potential to change behavior (by means of a behavior change technique taxonomy), potential to promote app use (by means of a gamification components taxonomy), and app quality (by means of the Mobile Application Rating Scale [MARS]). Results The most commonly implemented functions in the 38 reviewed asthma apps were tracking (30/38, 79%) and information (26/38, 68%) functions, followed by assessment (20/38, 53%) and notification (18/38, 47%) functions. On average, the reviewed apps applied 7.12 of 26 available behavior change techniques (standard deviation [SD]=4.46) and 4.89 of 31 available gamification components (SD=4.21). Average app quality was acceptable (mean=3.17/5, SD=0.58), whereas subjective app quality lied between poor and acceptable (mean=2.65/5, SD=0.87). Additionally, the sum scores of all review frameworks were significantly correlated (lowest correlation: r36=.33, P=.04 between

  11. Why invest in a national public health program for stroke? An example using Australian data to estimate the potential benefits and cost implications.

    Science.gov (United States)

    Cadilhac, Dominique A; Carter, Robert C; Thrift, Amanda G; Dewey, Helen M

    2007-10-01

    Stroke is the world's second leading cause of death in people aged over 60 years. Approximately 50,000 strokes occur annually in Australia with numbers predicted to increase by about one third over 10-years. Our objectives were to assess the economic implications of a public health program for stroke by: (1) predicting what potential health-gains and cost-offsets could be achieved; and (2) determining the net level of annual investment that would offer value-for-money. Lifetime costs and outcomes were calculated for additional cases that would benefit if 'current practice' was feasibly improved, estimated for one indicative year using: (i) local epidemiological data, coverage rates and costs; and (ii) pooled effect sizes from systematic reviews. blood pressure lowering; warfarin for atrial fibrillation; increased access to stroke units; intravenous thrombolysis and aspirin for ischemic events; and carotid endarterectomy. Value-for-money threshold: AUD$30,000/DALY recovered. Improved, prevention and management could prevent about 27,000 (38%) strokes in 2015. In present terms (2004), about 85,000 DALYs and AUD$1.06 billion in lifetime cost-offsets could be recovered. The net level of annual warranted investment was AUD$3.63 billion. Primary prevention, in particular blood pressure lowering, was most effective. A public health program for stroke is warranted.

  12. The USGS/EPA ''radon potential of the U.S.'' project: A case study in the application of geoscience information to public policy

    International Nuclear Information System (INIS)

    Schumann, R.R.; Gundersen, L.C.S.

    1993-01-01

    As part of an interagency agreement with the US Environmental Protection Agency (EPA), the US Geological Survey (USGS) has prepared a series of maps and reports, by state, describing and assessing the geologic radon potential of the United States. The documents were prepared with multiple uses in mind, including guidance for targeted radon sampling or information programs, to aid in the application of radon-resistant building codes, and as a starting point for more detailed investigations. The USGS and EPA were assisted in the planning and review stages by the Association of American State Geologists, and the draft reports were also reviewed by the state radon contact agencies (typically health departments or departments of environmental protection) and other state and federal agencies. A relative radon potential ranking scheme was developed by USGS to provide consistency and accountability. The scheme consists of a Radon Index, the sum of 5 individually-scored factors (geology, soil permeability, aerial radioactivity, architecture, and screening indoor radon data), and an associated Confidence Index, an expression of the quality and quantity of the data used to evaluate each factor. The assessments are presented on a scale that is useful for state- or regional-scale planning, but inapplicable to areas smaller than counties. The most common problems cited by the reviewers are: (1) the conflict of natural geologic boundaries and political boundaries; (2) the use of the NURE aerial radiometric data; (3) the use of short-term charcoal canister data as opposed to long-term annual average data; (4) the definition of ''high'' radon and the cost of dealing with the radon problem if ''high'' is 4 pCi/L; and (5) the potential misuse of geologic assessments by the public, the radon industry, and governments. The use of geological common sense in concert with policy decisions can alleviate many of the above problems

  13. The Potential of Mobile Apps for Improving Asthma Self-Management: A Review of Publicly Available and Well-Adopted Asthma Apps.

    Science.gov (United States)

    Tinschert, Peter; Jakob, Robert; Barata, Filipe; Kramer, Jan-Niklas; Kowatsch, Tobias

    2017-08-02

    Effective disease self-management lowers asthma's burden of disease for both individual patients and health care systems. In principle, mobile health (mHealth) apps could enable effective asthma self-management interventions that improve a patient's quality of life while simultaneously reducing the overall treatment costs for health care systems. However, prior reviews in this field have found that mHealth apps for asthma lack clinical evaluation and are often not based on medical guidelines. Yet, beyond the missing evidence for clinical efficacy, little is known about the potential apps might have for improving asthma self-management. The aim of this study was to assess the potential of publicly available and well-adopted mHealth apps for improving asthma self-management. The Apple App store and Google Play store were systematically searched for asthma apps. In total, 523 apps were identified, of which 38 apps matched the selection criteria to be included in the review. Four requirements of app potential were investigated: app functions, potential to change behavior (by means of a behavior change technique taxonomy), potential to promote app use (by means of a gamification components taxonomy), and app quality (by means of the Mobile Application Rating Scale [MARS]). The most commonly implemented functions in the 38 reviewed asthma apps were tracking (30/38, 79%) and information (26/38, 68%) functions, followed by assessment (20/38, 53%) and notification (18/38, 47%) functions. On average, the reviewed apps applied 7.12 of 26 available behavior change techniques (standard deviation [SD]=4.46) and 4.89 of 31 available gamification components (SD=4.21). Average app quality was acceptable (mean=3.17/5, SD=0.58), whereas subjective app quality lied between poor and acceptable (mean=2.65/5, SD=0.87). Additionally, the sum scores of all review frameworks were significantly correlated (lowest correlation: r 36 =.33, P=.04 between number of functions and gamification

  14. Radiation protection principles as applied to the disposal of long-lived solid radioactive waste and protection of the public. Commentary of ICRP publication 81 and publication 82

    International Nuclear Information System (INIS)

    Kosako, Toshiso

    2001-01-01

    This commentary is for ICRP Publication 81 concerning the disposal of long-lived solid radioactive waste to which the Publication 82 giving theoretical basis for protection of the public exposed for a long period. The primary object for prevention is the public in this disposal, which is quite different from the concept hitherto where the object is the facility. The essential points in the prevention are the definition and direction for the protection of future generations, critical group, potential exposures, protection optimization, principles in the technology and management, consistency of the principle, and evidence of observance to radiological standards. Dose constraint of 0.3 mSv/y or 10 -5 risk, reasonable measures taken for reduction of probable human invasion of its influence and observance to technological and control principles are recommended. Publication 82 principally describes and discusses the reference level for intervention and dose limits to the public due to action.(K.H.)

  15. Association of air pollution on birth outcomes in New Delhi - a pilot study on the potential of HMIS data for environmental public health tracking.

    Science.gov (United States)

    Magsumbol, Melina S; Singh, Archna; Ghosh, Arpita; Kler, Neelam; Garg, Pankaj; Thakur, Anup; Beg, Arshad; Srivastava, Atul; Hajat, Shakoor

    The study objective was to assess the gaps in current hospital health management information systems (ie. paper based records of prenatal, delivery, neonatal, discharge data) for environmental studies. This study also considers the feasibility of linking patient-level hospital data with ambient air pollution data recorded in real time by air quality monitoring stations. This retrospective hospital based cohort study used a semi-ecologic design to explore the association of air pollution with a neonate's birth weight and gestational age. Maternal and neonatal data from 2007-2012 were encoded and linked with air pollution data based on distance to the nearest air quality monitoring station. Completeness and accuracy of neonatal anthropometric measures, maternal demographic information, nutritional status and maternal risk factors (gestational diabetes, anaemia, hypertension, etc.) were assessed. The records of 10,565 births in Sir Ganga Ram hospital in New Delhi were encoded and linked with real time air quality data. These were records of women who reported a New Delhi address during the time of delivery. The distance of each address to all the monitoring stations were recorded. Birth records were assigned pollution exposure levels averaged across records from monitoring stations within 10 kilometers of the address during the pregnancy period. This pilot study will highlight the potential of hospital management information system in linking administrative hospital record data with information on environmental exposure. The linked health-exposure dataset can then be used for studying the impact of various environmental exposures on health outcomes. Mother's educational attainment, occupation, residential history, nutritional status, tobacco and alcohol use during pregnancy need to be documented for better health risk assessments or case management. Health institutions can provide data for public health researchers and environmental scientists and can serve as the

  16. The Potential Use of Legitimate Force for the Preservation of Order: Defining the Inherent Role of Public Police Through Policing Functions that cannot be Carried out by Private Police

    Directory of Open Access Journals (Sweden)

    Jasmina Arnež

    2016-12-01

    Full Text Available In the UK, private policing institutions have been rapidly increasing since the 1980s, so the lines between public- and private police have been blurred. This paper explores whether there is a policing function that is inherent in public police and if so, why it occupies this position. It integrates Rousseau’s social contract theory, Bittner’s definition of police functions, Brodeur’s reasoning on force and Loader and Walker’s concept of ‘policing as public good’ to argue that the potential use of legitimate force for the preservation of order is the function intrinsic to public police. It shows why it cannot and should not be carried out by private police and outlines how it depends on police legitimacy. It concludes with an abstract rethinking of public-state-police relations to determine that this function remains in the realm of public policing.

  17. A comparison of the immune responses of dogs exposed to canine distemper virus (CDV) — Differences between vaccinated and wild-type virus exposed dogs

    Science.gov (United States)

    Perrone, Danielle; Bender, Scott; Niewiesk, Stefan

    2010-01-01

    Canine distemper virus (CDV)-specific immune response was measured in different dog populations. Three groups of vaccinated or wild-type virus exposed dogs were tested: dogs with a known vaccination history, dogs without a known vaccination history (shelter dogs), and dogs with potential exposure to wild-type CDV. The use of a T-cell proliferation assay demonstrated a detectable CDV-specific T-cell response from both spleen and blood lymphocytes of dogs. Qualitatively, antibody assays [enzyme-linked immunosorbent assay (ELISA) and neutralization assay] predicted the presence of a T-cell response well, although quantitatively neither antibody assays nor the T-cell assay correlated well with each other. An interesting finding from our study was that half of the dogs in shelters were not vaccinated (potentially posing a public veterinary health problem) and that antibody levels in dogs living in an environment with endemic CDV were lower than in vaccinated animals. PMID:20885846

  18. A comparison of the immune responses of dogs exposed to canine distemper virus (CDV) - Differences between vaccinated and wild-type virus exposed dogs.

    Science.gov (United States)

    Perrone, Danielle; Bender, Scott; Niewiesk, Stefan

    2010-07-01

    Canine distemper virus (CDV)-specific immune response was measured in different dog populations. Three groups of vaccinated or wild-type virus exposed dogs were tested: dogs with a known vaccination history, dogs without a known vaccination history (shelter dogs), and dogs with potential exposure to wild-type CDV. The use of a T-cell proliferation assay demonstrated a detectable CDV-specific T-cell response from both spleen and blood lymphocytes of dogs. Qualitatively, antibody assays [enzyme-linked immunosorbent assay (ELISA) and neutralization assay] predicted the presence of a T-cell response well, although quantitatively neither antibody assays nor the T-cell assay correlated well with each other. An interesting finding from our study was that half of the dogs in shelters were not vaccinated (potentially posing a public veterinary health problem) and that antibody levels in dogs living in an environment with endemic CDV were lower than in vaccinated animals.

  19. Studies on persons exposed to plutonium

    International Nuclear Information System (INIS)

    Voelz, G.L.; Stebbings, J.H.; Hempelmann, L.H.; Haxton, L.K.; York, D.A.

    1978-01-01

    The results of four studies of persons exposed, or potentially exposed, to plutonium are summarized. The studies are: a five-year update on clinical examinations and health experience of 26 Manhattan District workers heavily exposed at Los Alamos in 1944 to 1945; a 30-year mortality follow-up of 224 white male workers with plutonium body burdens of 10 nCi or more; a review of cancer mortality rates between 1950 and 1969 among Los Alamos County, New Mexico, male residents, all of whom have worked in or have lived within a few kilometers of a major plutonium plant and other nuclear facilities; and a review of cancer incidence rates between 1969 and 1974 in male residents of Los Alamos County. No excess of mortality due to any cause was observed in the 224 male subjects with the highest plutonium exposures at Los Alamos. Clinical examinations of the Manhattan District workers, whose average age in 1976 was 56 years, show them to be active persons with diseases that are not unusual for their ages. The two deaths in this group over the past 30 years have not been due to cancer. Mortality and incidence data indicate no excess of lung cancer in Los Alamos County males

  20. Publicity and public relations

    Science.gov (United States)

    Fosha, Charles E.

    1990-01-01

    This paper addresses approaches to using publicity and public relations to meet the goals of the NASA Space Grant College. Methods universities and colleges can use to publicize space activities are presented.

  1. Potential economic benefits of public-private partnership (P3s) on reclaimed mine sites in the construction of the I-73/74 NHS corridor.

    Science.gov (United States)

    2012-02-01

    A public private partnership (PPP or P3), according to the FHWA, is a contractual agreement : between a public agency and a private entity for private sector participation in the delivery of : transportation projects. One of the most innovat...

  2. 3. cotrimoxazole prophylaxis compliance among hiv exposed infants

    African Journals Online (AJOL)

    Esem

    reported that their spouses knew about their HIV status and 65.7% said that they felt free to give their child cotrimoxazole in public.61.8% of the respondents did not know that there was a social support group for mothers/caretakers of HIV exposed infants in their community and 74.5% stated that there were misconceptions ...

  3. The Occupy Central (Umbrella) movement and mental health distress in the Hong Kong general public: political movements and concerns as potential structural risk factors of population mental health.

    Science.gov (United States)

    Lau, Joseph T F; Kim, Yoona; Wu, Anise M S; Wang, Zixin; Huang, Bishan; Mo, Phoenix K H

    2017-05-01

    Political tension, as expressed by mass movements such as the Occupy Central movement (2014) in Hong Kong, is a potential but understudied structural factor of population mental health. A random population-based telephone survey anonymously interviewed 344 Hong Kong Chinese adults aged 18-65 years during the 2 weeks since the termination date of the 2-month-long Occupy Central movement (15/12/2014). Linear regression models were fit using mental distress (depression, anxiety and negative mood) and self-perceived changes in mood/sleeping quality as dependent variables. Prevalence of participation in the movement was 10.5% (self), 17.7% (family members/relatives), and 34.0% (peers); 8.5% had participated for ≥2 days. Young age, but not participation, was associated with mental distress. In adjusted analysis, three types of responses to the movement (worry about safety, negative emotional responses to media reports, and conflicts with peers about the movement) and emotional responses to local political situations were significantly associated with all/some of the dependent variables related to mental distress. The variable on emotions toward local political situations was correlated with the three responses to the movement; it fully mediated the associations between such responses and mental distress. Many citizens participated in the movement, which was led by youths and might have increased the general public's mental distress. Negative personal responses to the movement and emotions toward political situations were potential risk factors. As the political tension would last and political pessimism is globally found, politics may have become a regular and persistent structural risk factor negatively affecting population mental health.

  4. Peace journalism where there is no war. Conflict-sensitive reporting on urban violence and public security in Brazil and its potential role in conflict transformation

    Directory of Open Access Journals (Sweden)

    Joice Biazoto

    2011-10-01

    Full Text Available The absence of war in a country like Brazil does not mean peace for its population. High murder rates, police killings, and violent urban conflict (in the favelas and beyond are part of Brazilians’ daily lives. The national media helps construct the discourses of violence which contribute to maintain the status quo – but can the media play a positive role in the conflict and become a force for peace? In attempting to determine whether Peace Journalism is a useful tool for reporting about urban violence in Brazil, this qualitative case study analyzes a special series in Rio de Janeiro newspaper O Globo about a novel public security model in the city – the Pacifier Police Units (UPP – by employing adapted De-Escalation-Oriented Conflict Coverage (DEOCC criteria. The analysis reveals a combination of escalation and de-escalation elements in the series, and while this particular example does not prove to be conflict sensitive, the Peace Journalism framework itself shows great potential if implemented to improve coverage of urban violence in Brazil.

  5. Use of principal component analysis in the evaluation of adherence to statin treatment: a method to determine a potential target population for public health intervention.

    Science.gov (United States)

    Latry, Philippe; Martin-Latry, Karin; Labat, Anne; Molimard, Mathieu; Peter, Claude

    2011-08-01

    The prevalence of statin use is high but adherence low. For public health intervention to be rational, subpopulations of nonadherent subjects must be defined. To categorise statin users with respect to patterns of reimbursement, this study was performed using the main French health reimbursement database for the Aquitaine region of south-western France. The cohort included subjects who submitted a reimbursement for at least one delivery of a statin (index) during the inclusion period (1st of September 2004-31st of December 2004). Indicators of adherence from reimbursement data were considered for principal component analysis. The 119,570 subjects included and analysed had a sex ratio of 1.1, mean (SD) age of 65.9 (11.9), and 13% were considered incident statin users. Principal component analysis found three dimensions that explained 67% of the variance. Using a K-means classification combined with a hierarchical ascendant classification, six groups were characterised. One group was considered nonadherent (10% of study population) and one group least adherent (1%). This novel application of principal component analysis identified groups that may be potential targets for intervention. The least adherent group appears to be one of the most appropriate because of both its relatively small size for case review with prescribing physicians and its very poor adherence. © 2010 The Authors Fundamental and Clinical Pharmacology © 2010 Société Française de Pharmacologie et de Thérapeutique.

  6. Visual evoked potentials in children prenatally exposed to methylmercury

    DEFF Research Database (Denmark)

    Yorifuji, Takashi; Murata, Katsuyuki; Bjerve, Kristian S

    2013-01-01

    Prenatal exposure to methylmercury can cause both neurobehavioral deficits and neurophysiological changes. However, evidence of neurotoxic effects within the visual nervous system is inconsistent, possibly due to incomplete statistical adjustment for beneficial nutritional factors. We evaluated t...

  7. Reprocessing of nonoptimally exposed holograms

    International Nuclear Information System (INIS)

    Phipps, G.S.; Robertson, C.E.; Tamashiro, F.M.

    1980-01-01

    Two reprocessing techniques have been investigated that are capable of correcting the effects of nonoptimum optical density of photographic amplitude holograms recorded on Agfa-Gevaert type 10E75 plates. In some cases a reprocessed hologram will exhibit a diffraction efficiency even higher than that obtainable from a hologram exposed and processed to the optimum density. The SNR of the reprocessed holograms is much higher than that of the same holograms belached with cupric bromide. In some cases the SNR approaches the optimum value for a properly exposed amplitude hologram. Subjective image quality and resolution of reprocessed hologram reconstructins appear to be no different than for normal single-development holograms. Repeated reprocessing is feasible and in some cases desirable as a means of increasing diffraction efficiency

  8. Publication Design.

    Science.gov (United States)

    Nelson, Roy Paul

    This book is designed to solve the problem of coordinating art and typography with content in publications. Through text and illustrations, this book suggests ways to make pages and spreads in magazines, newspapers, and books attractive and readable. As a book of techniques, it is directed at potential and practicing art directors, designers, and…

  9. Survey on Urinary Levels of Aflatoxins in Professionally Exposed Workers

    Directory of Open Access Journals (Sweden)

    Fulvio Ferri

    2017-03-01

    Full Text Available Feed mill workers may handle or process maize contaminated with aflatoxins (AFs. This condition may lead to an unacceptable intake of toxins deriving from occupational exposure. This study assessed the serological and urinary levels of AFs in workers exposed to potentially contaminated dusts in two mills. From March to April 2014, blood and urine samples were collected, on Monday and Friday morning of the same working week from 29 exposed workers and 30 non-exposed controls. AFs (M1, G2, G1, B1, B2 and aflatoxicol (AFOH A were analyzed. Each subject filled in a questionnaire to evaluate potential food-borne exposures to mycotoxins. AFs contamination in environmental dust was measured in both plants. No serum sample was found to be positive. Seventy four percent of urine samples (73.7% revealed AFM1 presence. AFM1 mean concentration was 0.035 and 0.027 ng/mL in exposed and non-exposed workers, respectively (p = 0.432; the concentration was slightly higher in Friday’s than in Monday’s samples, in exposed workers, 0.040 versus (vs. 0.031 and non-exposed controls (0.030 vs. 0.024, p = 0.437. Environmental AFs contamination ranged from 7.2 to 125.4 µg/kg. The findings of this study reveal the presence of higher AFs concentration in exposed workers than in non-exposed controls, although these differences are to be considered consistent with random fluctuations.

  10. Review of the health effects of wildland fire smoke on wildland firefighters and the public

    Science.gov (United States)

    Olorunfemi Adetona; Timothy E. Reinhardt; Joe Domitrovich; George Broyles; Anna M. Adetona; Michael T. Kleinman; Roger D. Ottmar; Luke P. Naeher

    2016-01-01

    Each year, the general public and wildland firefighters in the US are exposed to smoke from wildland fires. As part of an effort to characterize health risks of breathing this smoke, a review of the literature was conducted using five major databases, including PubMed and MEDLINE Web of Knowledge, to identify smoke components that present the highest hazard potential,...

  11. Moving beyond Fuzy Altruism in Business-Education Relationships: The Potential of the Georgia Alliance for Public Education. Supporting Leaders for Tomorrow, Occasional Paper #8.

    Science.gov (United States)

    Trimble, Grace

    Georgia's business leadership is concerned about that state's public education system which has consistently ranked near the bottom of the educational ladder. In 1986, the Quality Basic Education (QBE) Act became law, and its provisions are described in this document. The Georgia Alliance for Public Education (the Alliance) was mobilized to…

  12. Indoor air pollution: a public health perspective

    International Nuclear Information System (INIS)

    Spengler, J.D.; Sexton, K.

    1983-01-01

    Although official efforts to control air pollution have traditionally focused on outdoor air, it is now apparent that elevated contaminant concentrations are common inside some private and public buildings. Concerns about potential public health problems due to indoor air pollution are based on evidence that urban residents typically spend more than 90 percent of their time indoors, concentrations of some contaminants are higher indoors than outdoors, and for some pollutants personal exposures are not characterized adequately by outdoor measurements. Among the more important indoor contaminants associated with health or irritation effects are passive tobacco smoke, radon decay products, carbon monoxide, nitrogen dioxide, formaldehyde, asbestos fibers, microorganisms, and aeroallergens. Efforts to assess health risks associated with indoor air pollution are limited by insufficient information about the number of people exposed, the pattern and severity of exposures, and the health consequences of exposures. An overall strategy should be developed to investigate indoor exposures, health effects, control options, and public policy alternatives

  13. The Challenges of Projecting the Public Health Impacts of Marijuana Legalization in Canada Comment on "Legalizing and Regulating Marijuana in Canada: Review of Potential Economic, Social, and Health Impacts".

    Science.gov (United States)

    Lake, Stephanie; Kerr, Thomas

    2016-09-10

    A recent editorial in this journal provides a summary of key economic, social, and public health considerations of the forthcoming legislation to legalize, regulate, and restrict access to marijuana in Canada. As our government plans to implement an evidence-based public health framework for marijuana legalization, we reflect and expand on recent discussions of the public health implications of marijuana legalization, and offer additional points of consideration. We select two commonly cited public concerns of marijuana legalization - adolescent usage and impaired driving - and discuss how the underdeveloped and equivocal body of scientific literature surrounding these issues limits the ability to predict the effects of legalization. Finally, we discuss the potential for some potential public health benefits of marijuana legalization - specifically the potential for marijuana to be used as a substitute to opioids and other risky substance use - that have to date not received adequate attention. © 2017 The Author(s); Published by Kerman University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

  14. Posible impacto en la salud pública del encallamiento de cetáceos en Costa Rica Potential public health impact of the stranding of cetaceans

    Directory of Open Access Journals (Sweden)

    Olga Rivas-Solano

    2013-06-01

    the attention of tourists and locals, which tend to have close contact with the animal, mostly to return it to the sea. This potentiates the risk of transmission of pathogenic strains from marine mammals to humans and to other animals. In our country, a research project has been conducted during 2009 and 2011 by experts from public universities, government institutions and Keto Foundation. As part of this project, educational workshops have been addressed to healthcare professionals, community leaders, and local authorities, with the purpose of training them in the correct management of cetacean stranding, basically to prevent situations of public health risk.

  15. Educating the future public health workforce: do schools of public health teach students about the private sector?

    Science.gov (United States)

    Rutkow, Lainie; Traub, Arielle; Howard, Rachel; Frattaroli, Shannon

    2013-01-01

    Recent surveys indicate that approximately 40% of graduates from schools of public health are employed within the private sector or have an employer charged with regulating the private sector. These data suggest that schools of public health should provide curricular opportunities for their students--the future public health workforce--to learn about the relationship between the private sector and the public's health. To identify opportunities for graduate students in schools of public health to select course work that educates them about the relationship between the private sector and public health. We systematically identified and analyzed data gathered from publicly available course titles and descriptions on the Web sites of accredited schools of public health. Data were collected in the United States. The sample consisted of accredited schools of public health. Descriptions of the number and types of courses that schools of public health offer about the private sector and identification of how course descriptions frame the private sector relative to public health. We identified 104 unique courses with content about the private sector's relationship to public health. More than 75% of accredited schools of public health offered at least 1 such course. Nearly 25% of identified courses focused exclusively on the health insurance industry. Qualitative analysis of the data revealed 5 frames used to describe the private sector, including its role as a stakeholder in the policy process. Schools of public health face a curricular gap, with relatively few course offerings that teach students about the relationship between the private sector and the public's health. By developing new courses or revising existing ones, schools of public health can expose the future public health workforce to the varied ways public health professionals interact with the private sector, and potentially influence students' career paths.

  16. Screening and surveillance of workers exposed to mineral dusts

    Energy Technology Data Exchange (ETDEWEB)

    Wagner, G.R.

    1997-12-31

    This publication resulted from a World Health Organisation initiated project to investigate the harmonisation of definitions, approaches and methodologies for the screening and surveillance of workers exposed to mineral dust. The first part of the book provides definitions of screening and surveillance and describes the main elements of such programmes. The second part discusses the practical aspect of the screening and surveillance of working populations exposed to crystalline silica, coal mine dust and asbestos. Although no single set of guidelines is applicable to the development and implementation of a programme for the screening and surveillance of workers exposed to mineral dust, the recommendations, together with certain caveats, should provide a useful starting point. Annexes provide examples of existing programmes in various countries and environments and discuss the use and interpretation of questionnaires, lung spirometry and chest radiography. Overall the book should be of interest to occupational health professionals.

  17. Occurrence of zoonotic tuberculosis in occupationally exposed high-risk groups in Peshawar, Pakistan

    Directory of Open Access Journals (Sweden)

    Irfan Khattak

    2016-01-01

    Conclusion: Zoonotic TB is a significant public health issue among professionally exposed groups in Peshawar, Pakistan, and suggests a need for further detailed investigations of the disease in this and similar areas.

  18. Advances in treating exposed fractures.

    Science.gov (United States)

    Nogueira Giglio, Pedro; Fogaça Cristante, Alexandre; Ricardo Pécora, José; Partezani Helito, Camilo; Lei Munhoz Lima, Ana Lucia; Dos Santos Silva, Jorge

    2015-01-01

    The management of exposed fractures has been discussed since ancient times and remains of great interest to present-day orthopedics and traumatology. These injuries are still a challenge. Infection and nonunion are feared complications. Aspects of the diagnosis, classification and initial management are discussed here. Early administration of antibiotics, surgical cleaning and meticulous debridement are essential. The systemic conditions of patients with multiple trauma and the local conditions of the limb affected need to be taken into consideration. Early skeletal stabilization is necessary. Definitive fixation should be considered when possible and provisional fixation methods should be used when necessary. Early closure should be the aim, and flaps can be used for this purpose.

  19. Educator Sexual Misconduct: Exposing or Causing Learners to Be Exposed to Child Pornography or Pornography

    Directory of Open Access Journals (Sweden)

    Susan Coetzee

    2016-02-01

    Full Text Available he law recognises that non-contact sexual offences can cause harm and several offences were created to regulate non-contact sexual child abuse offences. Several of these offences deal with the exposure or causing exposure of children to child pornography or pornography. Sexual grooming of children and the “Exposure or display of or causing exposure or display of child pornography or pornography to children” are criminalised in sections 18(2 and 19 of the Criminal Law (Sexual Offences and Related Matters Amendment Act 32 of 2007. And offences in relation to exposing children to disturbing, harmful and age-inappropriate materials are criminalised in sections 24A(2 and (4 of the Films and Publications Act 65 of 1996. In this article the author considered the content of the offences of “Exposure or display of or causing exposure or display of child pornography or pornography to children” in relation to the other offences dealing with exposure of children to child pornography or pornography. Benchmarked against these criminal offences the author then conceptualised exposing learners, or causing the exposure of learners to child pornography or pornography as forms of educator misconduct. The seriousness that should be attached to these forms of misconduct was considered in light of the various criminal offences. The review of the criminal offences and the forms of educator misconduct brought the ineffectiveness of current forms of serious educator misconduct to the fore. There is no form of serious misconduct that covers the transgression of educators who expose learners to child pornography or pornography that can be classified as “XX”. In conclusion a suggestion is made with regard to how a new form of serious misconduct could be worded so as to cover this gap, eg An educator must be dismissed if he or she is found guilty of – (g exposing a learner to or causing exposure of a learner to material classified as “Refused” or

  20. Public perception of environmental quality

    DEFF Research Database (Denmark)

    Lech Cantuaria, Manuella

    outcomes. The quality of the environment and its impacts on communities’ health consist in a growing source of public and government concern and therefore, are being widely investigated in epidemiological studies. These studies are usually designed so that potential errors are minimized and high...... of the cases, investigating the impacts that these issues may have on health effect estimates and the interpretation of epidemiological results. For this purpose, the thesis is based on two distinct case studies: the first one refers to non-urban communities of Denmark living nearby agricultural and livestock...... farming activities; while the second case study analyzes urban populations living in the capital city of Switzerland, being constantly exposed to noise and air pollution from traffic sources. The following methodological issues are hereby confronted throughout the thesis: 1) misclassification...

  1. Addressing the disconnect between public health science and personalised health care: the potential role of cluster analysis in combination with multi-criteria decision analysis

    DEFF Research Database (Denmark)

    Kaltoft, Mette Kjer; Dowie, Jack; Turner, Robin

    2013-01-01

    Background: Public health promotion and person-centred health care are being pursued simultaneously, with little attempt to resolve the conflict between them. One necessary step is to accept that health-care decisions involve multiple criteria and hence are preference sensitive. A second...... is to arrive at the necessary compromise between an individualised public policy (using each individual's preferences) and a deindividualised policy (using mean population preferences) in a more rigorous and transparent way. We show how cluster analysis can be combined with multi-criteria decision analysis...... (MCDA) to facilitate progression from variable-centred to person-centred public health, albeit at a subgroup level. Methods: Cluster analysis encompasses various techniques designed to detect patterns in the characteristics of individuals to establish the basis for policy decisions targeted at subgroups...

  2. Limit State of Trapezoidal Metal Sheets Exposed to Concentrated Load

    OpenAIRE

    Kateřina Jurdová

    2013-01-01

    In most industrial compounds are used trapezoidal metal sheets like a roof decks. These trapezoidal metal sheets are exposed by concentrated loads, usually by service loads arise from installation of air distribution, sanitary distribution, sprinkler system or wiring installation. In objects of public facilities (like shopping centre, tennis hall, etc.) they can be used for hanging advertising posters etc, too. These systems work as “building kit”. These anchoring systems are represented by c...

  3. Under-exposed. And if radiations were good for you?

    International Nuclear Information System (INIS)

    Gay, Michel

    2016-01-01

    This book is in fact a synthesis of an American publication (Under-Exposed). The author, with its characteristic style, aims at giving a positive perception of nuclear energy, at denying catastrophist speeches on nuclear energy, and more particularly on radioactivity: low doses are not dangerous, and even can be useful for our health and well-being, notably in many spa resorts. Thus, he also aims at struggling against what he considers as an ecological obscurantism

  4. Does the Common Core Further Democracy? A Response to "The Common Core and Democratic Education: Examining Potential Costs and Benefits to Public and Private Autonomy"

    Science.gov (United States)

    Neem, Johann N.

    2018-01-01

    The Common Core does not advance democratic education. Far from it, the opening section of the language standards argues that the goal of public K-12 education is "college and career readiness." Only at the end of their introductory section do the Common Core's authors suggest that K-12 education has any goals beyond the economic:…

  5. Potencial hidrogeniônico de soluções de cloridrato de dobutamina expostas a condições ambientais de unidades de cuidados intensivos neonatais Hydrogen-ion potential of dobutamine hydrochloride solutions exposed to environmental conditions of neonatal intensive care units

    Directory of Open Access Journals (Sweden)

    Lidiane L. Reis

    2009-12-01

    Full Text Available OBJETIVO: Verificar o potencial hidrogeniônico (pH de soluções de cloridrato de dobutamina sob condições ambientais que mimetizam unidades de cuidados intensivos neonatais. MÉTODOS: Analisou-se pH do fármaco em solução glicosada 5% ou NaCl 0,9% segundo temperatura (22 e 37 °C, luz (escuro, lâmpadas fluorescentes ambiente e equipamento de fototerapia e equipos (incolor e âmbar em intervalos de tempo (0, 1, 24, 48, 72 e 96 horas. RESULTADOS: Evidenciaram-se valores próximos de pH do fármaco na apresentação comercial e diluído. Obteve-se média de pH de 3,45±0,19 a 22 °C e de 3,55±0,20 a 37 °C. A média de pH das soluções mantidas no escuro foi de 3,62±0,09, na luz ambiente, de 3,63±0,07, e sob fototerapia, de 3,31±0,16. Soluções em equipos incolores tiveram média menor (3,41±0,24 do que em âmbares (3,52±0,15. Obtiveram-se menores valores de pH nas soluções sob fototerapia em equipos incolores (3,17±0,03 do que em âmbares (3,55±0,03. CONCLUSÃO: Sob a luz da fototerapia houve maior variação do pH das soluções, e o emprego de equipos âmbares minimizou tal efeito.OBJECTIVE: To verify the hydrogen-ion potential (pH of dobutamine hydrochloride solutions under environmental conditions similar to those of neonatal intensive care units. METHODS: We analyzed the pH of the drug diluted in 5% dextrose in water or 0.9% NaCl under different conditions of temperature (22 and 37 °C and light (dark, fluorescent light bulbs, and phototherapy equipment, using colorless and amber intravenous sets at time intervals of 0, 1, 24, 48, 72, and 96 hours. RESULTS: The pH values of the marketed form of the drug and the diluted drug were similar. The pH means were 3.45±0.19 at 22 °C and 3.55±0.20 at 37 °C. The average of the pH according to light conditions were as follows: in the dark = 3.62±0.09, under room light = 3.63±0.07, and exposed to phototherapy = 3.31±0.16. Solutions stored in colorless intravenous sets had a lower

  6. Water infiltration into exposed fractured rock surfaces

    International Nuclear Information System (INIS)

    Rasmussen, T.C.; Evans, D.D.

    1993-01-01

    Fractured rock media are present at many existing and potential waste disposal sites, yet characterization data and physical relationships are not well developed for such media. This study focused on water infiltration characteristics of an exposed fractured rock as an approach for defining the upper boundary condition for unsaturated-zone water percolation and contaminant transport modeling. Two adjacent watersheds of 0.24 and 1.73 ha with slopes up to 45% were instrumented for measuring rainfall and runoff. Fracture density was measured from readily observable fracture traces on the surface. Three methods were employed to evaluate the rainfall-runoff relationship. The first method used the annual totals and indicated that only 22.5% of rainfall occurred as runoff for the 1990-1991 water year, which demonstrates a high water intake rate by the exposed fracture system. The second method employed total rainfall and runoff for individual storms in conjunction with the commonly used USDA Soil Conservation Service curve number method developed for wide ranges of soils and vegetation. Curve numbers between 75 and 85 were observed for summer and winter storms with dry antecedent runoff conditions, while values exceeded 90 for wet conditions. The third method used a mass-balance approach for four major storms, which indicated that water intake rates ranged from 2.0 to 7.3 mm h -1 , yielding fracture intake velocities ranging from 122 to 293 m h -1 . The three analyses show the complexity of the infiltration process for fractured rock. However, they contribute to a better understanding of the upper boundary condition for predicting contaminant transport through an unsaturated fractured rock medium. 17 refs., 4 figs., 1 tab

  7. Thorium in occupationally exposed men

    International Nuclear Information System (INIS)

    Stehney, A. F.

    1999-01-01

    Higher than environmental levels of 232 Th have been found in autopsy samples of lungs and other organs from four former employees of a thorium refinery. Working periods of the subjects ranged from 3 to 24 years, and times from end of work to death ranged from 6 to 31 years. Examination of the distribution of thorium among the organs revealed poor agreement with the distribution calculated from the dosimetric models in Publication 30 of the International Commission on Radioprotection (ICRP). Concentrations in the lungs relative to pulmonary lymph nodes, bone or liver were much higher than calculated from the model for class Y thorium and the exposure histories of the workers. Much better agreement was found with more recently proposed models in Publications 68 and 69 of the ICRP. Radiation doses estimated from the amounts of thorium in the autopsy samples were compatible with health studies that found no significant difference in mortality from that of the general population of men in the US

  8. The essence of the notion of «professional potential» within the framework of academic field of public administration

    Directory of Open Access Journals (Sweden)

    I. V. Polishchuk

    2016-07-01

    Conclusions of the research. Therefore professional potential of civil servants is a multifaceted characteristic of an individual that includes objective and subjective factors, latent capabilities, theoretical knowledge, empirical skills, practical experience, psychophysiological qualities, professional competence.

  9. Sociodemographic variations in the amount, duration and cost of potentially preventable hospitalisation for chronic conditions among Aboriginal and non-Aboriginal Australians: a period prevalence study of linked public hospital data

    OpenAIRE

    Banham, David; Chen, Tenglong; Karnon, Jonathan; Brown, Alex; Lynch, John

    2017-01-01

    Objectives To determine disparities in rates, length of stay (LOS) and hospital costs of potentially preventable hospitalisations (PPH) for selected chronic conditions among Aboriginal and non-Aboriginal South Australians (SA), then examine associations with area-level socioeconomic disadvantage and remoteness. Setting Period prevalence study using linked, administrative public hospital records. Participants Participants included all SA residents in 2005–2006 to 2010–2011. Analysis focused on...

  10. Ethnic minority health in Vietnam: a review exposing horizontal inequity

    Directory of Open Access Journals (Sweden)

    Mats Målqvist

    2013-03-01

    Full Text Available Background: Equity in health is a pressing concern and reaching disadvantaged populations is necessary to close the inequity gap. To date, the discourse has predominately focussed on reaching the poor. At the same time and in addition to wealth, other structural determinants that influence health outcomes exist, one of which is ethnicity. Inequities based on group belongings are recognised as ‘horizontal’, as opposed to the more commonly used notion of ‘vertical’ inequity based on individual characteristics. Objective: The aim of the present review is to highlight ethnicity as a source of horizontal inequity in health and to expose mechanisms that cause and maintain this inequity in Vietnam. Design: Through a systematic search of available academic and grey literature, 49 publications were selected for review. Information was extracted on: a quantitative measures of health inequities based on ethnicity and b qualitative descriptions explaining potential reasons for ethnicity-based health inequities. Results: Five main areas were identified: health-care-seeking and utilization, maternal and child health, nutrition, infectious diseases, and oral health and hygiene. Evidence suggests the presence of severe health inequity in health along ethnic lines in all these areas. Research evidence also offers explanations derived from both external and internal group dynamics to this inequity. It is reported that government policies and programs appear to be lacking in culturally adaptation and sensitivity, and examples of bad attitudes and discrimination from health staff toward minority persons were identified. In addition, traditions and patriarchal structures within ethnic minority groups were seen to contribute to the maintenance of harmful health behaviors within these groups. Conclusion: Better understandings of the scope and pathways of horizontal inequities are required to address ethnic inequities in health. Awareness of ethnicity as a

  11. Ethnic minority health in Vietnam: a review exposing horizontal inequity

    Science.gov (United States)

    Målqvist, Mats; Hoa, Dinh Thi Phuong; Liem, Nguyen Thanh; Thorson, Anna; Thomsen, Sarah

    2013-01-01

    Background Equity in health is a pressing concern and reaching disadvantaged populations is necessary to close the inequity gap. To date, the discourse has predominately focussed on reaching the poor. At the same time and in addition to wealth, other structural determinants that influence health outcomes exist, one of which is ethnicity. Inequities based on group belongings are recognised as ‘horizontal’, as opposed to the more commonly used notion of ‘vertical’ inequity based on individual characteristics. Objective The aim of the present review is to highlight ethnicity as a source of horizontal inequity in health and to expose mechanisms that cause and maintain this inequity in Vietnam. Design Through a systematic search of available academic and grey literature, 49 publications were selected for review. Information was extracted on: a) quantitative measures of health inequities based on ethnicity and b) qualitative descriptions explaining potential reasons for ethnicity-based health inequities. Results Five main areas were identified: health-care-seeking and utilization, maternal and child health, nutrition, infectious diseases, and oral health and hygiene. Evidence suggests the presence of severe health inequity in health along ethnic lines in all these areas. Research evidence also offers explanations derived from both external and internal group dynamics to this inequity. It is reported that government policies and programs appear to be lacking in culturally adaptation and sensitivity, and examples of bad attitudes and discrimination from health staff toward minority persons were identified. In addition, traditions and patriarchal structures within ethnic minority groups were seen to contribute to the maintenance of harmful health behaviors within these groups. Conclusion Better understandings of the scope and pathways of horizontal inequities are required to address ethnic inequities in health. Awareness of ethnicity as a determinant of health, not

  12. Potential public health significance of faecal contamination and multidrug-resistant Escherichia coli and Salmonella serotypes in a lake in India.

    Science.gov (United States)

    Abhirosh, C; Sherin, V; Thomas, A P; Hatha, A A M; Mazumder, A

    2011-06-01

    To assess the prevalence of faecal coliform bacteria and multiple drug resistance among Escherichia coli and Salmonella serotypes from Vembanadu Lake. Systematic microbiological testing. Monthly collection of water samples were made from ten stations on the southern and northern parts of a salt water regulator constructed in Vembanadu Lake in order to prevent incursion of seawater during certain periods of the year. Density of faecal colifrom bacteria was estimated. E. coli and Salmonella were isolated and their different serotypes were identified. Antibiotic resistance analysis of E. coli and Salmonella serotypes was done and the MAR index of individual isolates was calculated. Density of faecal coliform bacteria ranged from mean MPN value 2900 -7100/100ml. Results showed multiple drug resistance pattern among the bacterial isolates. E. coli showed more than 50% resistance to amickacin, oxytetracycline, streptomycin, tetracycline and kanamycin while Salmonella showed high resistance to oxytetracycline, streptomycin, tetracycline and ampicillin. The MAR indexing of the isolates showed that they have originated from high risk source such as humans, poultry and dairy cows. The high density of faecal coliform bacteria and prevalence of multi drug resistant E. coli and Salmonella serotypes in the lake may pose severe public health risk through related water borne and food borne outbreaks. Copyright © 2011 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

  13. Public Values

    DEFF Research Database (Denmark)

    Beck Jørgensen, Torben; Rutgers, Mark R.

    2015-01-01

    administration is approached in terms of processes guided or restricted by public values and as public value creating: public management and public policy-making are both concerned with establishing, following and realizing public values. To study public values a broad perspective is needed. The article suggest......This article provides the introduction to a symposium on contemporary public values research. It is argued that the contribution to this symposium represent a Public Values Perspective, distinct from other specific lines of research that also use public value as a core concept. Public...... a research agenda for this encompasing kind of public values research. Finally the contributions to the symposium are introduced....

  14. Exploring the complexities of leprosy-related stigma and the potential of a socio-economic intervention in a public health context in Indonesia

    NARCIS (Netherlands)

    Dadun,; Peters, Ruth; Lusli, Mimi; Miranda-Galarza, Beatriz; Van Brakel, Wim; Zweekhorst, Marjolein; Damayanti, Rita; Irwanto, A.; Bunders-Aelen, J.G.F.

    2016-01-01

    Purpose: This article explores the complexities of leprosy-related stigma and the potential effectiveness of a socio-economic intervention in Cirebon District, Indonesia. Methods: A qualitative approach was adopted. 53 people affected by leprosy were interviewed, and 17 focus group discussions were

  15. Impact of future urban form on the potential to reduce greenhouse gas emissions from residential, commercial and public buildings in Utsunomiya, Japan

    International Nuclear Information System (INIS)

    Ishii, Satoshi; Tabushi, Shoichi; Aramaki, Toshiya; Hanaki, Keisuke

    2010-01-01

    Energy-saving technologies' applicability to making cities more environmentally sustainable can be strongly influenced by the city's form, building uses and their density pattern. Technological developments have clearly shown specific urban forms to be more conducive to installing certain mitigation technologies. In this study, the capacity for implementation and impacts on energy savings and subsequent greenhouse gas (GHG) reduction potential of mitigation technologies such as photovoltaic cells (PV) and combined heat and power (CHP) technologies were analysed with respect to three potential urban forms (high density centralised, medium density averaged and low density de-centralized) for Utsunomiya City, Japan. Given current building use patterns, scenarios for 2030 and 2050, showed the medium density averaged form, which benefits from both PV and CHP technologies, to outperform the other forms, resulting in an energy savings and GHG reduction potential of 27.6% in 2030 and 67.6% in 2050. Interestingly, GHG reduction in 2050 was primarily attributable to PV, while CHP technology had the greater influence in 2030. Despite the limitation of the analysis, the study provides a useful insight, highlighting the relationship between urban forms and GHG reduction potential by two energy-saving technologies.

  16. Whistleblowing and the bioethicist's public obligations.

    Science.gov (United States)

    MacDougall, D Robert

    2014-10-01

    Bioethicists are sometimes thought to have heightened obligations by virtue of the fact that their professional role addresses ethics or morals. For this reason it has been argued that bioethicists ought to "whistleblow"--that is, publicly expose the wrongful or potentially harmful activities of their employer--more often than do other kinds of employees. This article argues that bioethicists do indeed have a heightened obligation to whistleblow, but not because bioethicists have heightened moral obligations in general. Rather, the special duties of bioethicists to act as whistleblowers are best understood by examining the nature of the ethical dilemma typically encountered by private employees and showing why bioethicists do not encounter this dilemma in the same way. Whistleblowing is usually understood as a moral dilemma involving conflicting duties to two parties: the public and a private employer. However, this article argues that this way of understanding whistleblowing has the implication that professions whose members identify their employer as the public-such as government employees or public servants--cannot consider whistleblowing a moral dilemma, because obligations are ultimately owed to only one party: the public. The article contends that bioethicists--even when privately employed--are similar to government employees in the sense that they do not have obligations to defer to the judgments of those with private interests. Consequently, bioethicists may be considered to have a special duty to whistleblow, although for different reasons than those usually cited.

  17. Behavioral changes in fish exposed to phytoestrogens

    International Nuclear Information System (INIS)

    Clotfelter, Ethan D.; Rodriguez, Alison C.

    2006-01-01

    We investigated the behavioral effects of exposure to waterborne phytoestrogens in male fighting fish, Betta splendens. Adult fish were exposed to a range of concentrations of genistein, equol, β-sitosterol, and the positive control 17β-estradiol. The following behaviors were measured: spontaneous swimming activity, latency to respond to a perceived intruder (mirror reflection), intensity of aggressive response toward a perceived intruder, probability of constructing a nest in the presence of a female, and the size of the nest constructed. We found few changes in spontaneous swimming activity, the latency to respond to the mirror, and nest size, and modest changes in the probability of constructing a nest. There were significant decreases, however, in the intensity of aggressive behavior toward the mirror following exposure to several concentrations, including environmentally relevant ones, of 17β-estradiol, genistein, and equol. This suggests that phytoestrogen contamination has the potential to significantly affect the behavior of free-living fishes. - Environmentally relevant concentrations of phytoestrogens reduce aggressive behavior in fish

  18. The role and potentialities of the NRPI in the education of the health professionals and in the public information in the field of radiation protection in medical exposure

    International Nuclear Information System (INIS)

    Zackova, H.; Horakova, I.

    2008-01-01

    The attention is paid to the role of the National Radiation Protection Institute (NRPI) in the support of the education on the pregraduate and postgraduate level. On pregraduate level the NRPI is engaged in education of the students of the Faculty of Nuclear Sciences and Physical Engineering (FNSPE) in the field of radiation protection and radiological physics. On the postgraduate level there is an important role of NRPI in the postgraduate education of the health professionals. This education can take advantage of the more than the thirty years cooperation between NRPI and IPVZ (Institute for postgraduate medical education). In the presentation the important data and experience of the courses of radiation protection organized for health professionals will be ShOWll. In the presentation there are also presented activities of the division of medical exposures of the NRPI, which are pointing to the public information. Some typical questions, which have been addressed to NRPI are brought forward and discussed. (authors)

  19. BlueHealth: a study programme protocol for mapping and quantifying the potential benefits to public health and well-being from Europe’s blue spaces

    Science.gov (United States)

    White, Mathew P; Albin, Maria; Bell, Simon; Elliott, Lewis R; Gascón, Mireia; Gualdi, Silvio; Mancini, Laura; Nieuwenhuijsen, Mark J; Sarigiannis, Denis A; van den Bosch, Matilda; Wolf, Tanja; Wuijts, Susanne; Fleming, Lora E

    2017-01-01

    Introduction Proximity and access to water have long been central to human culture and accordingly deliver countless societal benefits. Over 200 million people live on Europe’s coastline, and aquatic environments are the top recreational destination in the region. In terms of public health, interactions with ‘blue space’ (eg, coasts, rivers, lakes) are often considered solely in terms of risk (eg, drowning, microbial pollution). Exposure to blue space can, however, promote health and well-being and prevent disease, although underlying mechanisms are poorly understood. Aims and methods The BlueHealth project aims to understand the relationships between exposure to blue space and health and well-being, to map and quantify the public health impacts of changes to both natural blue spaces and associated urban infrastructure in Europe, and to provide evidence-based information to policymakers on how to maximise health benefits associated with interventions in and around aquatic environments. To achieve these aims, an evidence base will be created through systematic reviews, analyses of secondary data sets and analyses of new data collected through a bespoke international survey and a wide range of community-level interventions. We will also explore how to deliver the benefits associated with blue spaces to those without direct access through the use of virtual reality. Scenarios will be developed that allow the evaluation of health impacts in plausible future societal contexts and changing environments. BlueHealth will develop key inputs into policymaking and land/water-use planning towards more salutogenic and sustainable uses of blue space, particularly in urban areas. Ethics and dissemination Throughout the BlueHealth project, ethics review and approval are obtained for all relevant aspects of the study by the local ethics committees prior to any work being initiated and an ethics expert has been appointed to the project advisory board. So far, ethical approval

  20. BlueHealth: a study programme protocol for mapping and quantifying the potential benefits to public health and well-being from Europe's blue spaces.

    Science.gov (United States)

    Grellier, James; White, Mathew P; Albin, Maria; Bell, Simon; Elliott, Lewis R; Gascón, Mireia; Gualdi, Silvio; Mancini, Laura; Nieuwenhuijsen, Mark J; Sarigiannis, Denis A; van den Bosch, Matilda; Wolf, Tanja; Wuijts, Susanne; Fleming, Lora E

    2017-06-14

    Proximity and access to water have long been central to human culture and accordingly deliver countless societal benefits. Over 200 million people live on Europe's coastline, and aquatic environments are the top recreational destination in the region. In terms of public health, interactions with 'blue space' (eg, coasts, rivers, lakes) are often considered solely in terms of risk (eg, drowning, microbial pollution). Exposure to blue space can, however, promote health and well-being and prevent disease, although underlying mechanisms are poorly understood. The BlueHealth project aims to understand the relationships between exposure to blue space and health and well-being, to map and quantify the public health impacts of changes to both natural blue spaces and associated urban infrastructure in Europe, and to provide evidence-based information to policymakers on how to maximise health benefits associated with interventions in and around aquatic environments. To achieve these aims, an evidence base will be created through systematic reviews, analyses of secondary data sets and analyses of new data collected through a bespoke international survey and a wide range of community-level interventions. We will also explore how to deliver the benefits associated with blue spaces to those without direct access through the use of virtual reality. Scenarios will be developed that allow the evaluation of health impacts in plausible future societal contexts and changing environments. BlueHealth will develop key inputs into policymaking and land/water-use planning towards more salutogenic and sustainable uses of blue space, particularly in urban areas. Throughout the BlueHealth project, ethics review and approval are obtained for all relevant aspects of the study by the local ethics committees prior to any work being initiated and an ethics expert has been appointed to the project advisory board. So far, ethical approval has been obtained for the BlueHealth International Survey and

  1. New media applications and their potential for the advancement of public perceptions of archaeoastronomy and for the testing of archaeoastronomical hypotheses.

    Science.gov (United States)

    MacDonald, J.

    This paper looks at the use of astronomical programmes and the development of new media modeling techniques as a means to better understand archaeoastronomy. The paper also suggests that these new methods and technologies are a means of furthering the public perceptions of archaeoastronomy and the important role that 'astronomy' played in the history and development of human culture. This discussion is rooted in a computer simulation of Stonehenge and its land and skyscape. The integration of the astronomy software allows viewing horizon astronomical lignments in relation to digitally recreated Neolithic/Early Bronze Age (EBA) monumental architecture. This work shows how modern virtual modelling techniques can be a tool for testing archaeoastronomical hypotheses, as well as a demonstrative tool for teaching and promoting archaeoastronomy in mainstream media.

  2. Comparisons of the risks and potential detriments of various energetic alternatives as a basis for adequate public acceptance - Looking for new ways of communication

    International Nuclear Information System (INIS)

    Osmachkin, V.S.

    1998-01-01

    It is widely adopted that modern energy production technologies (and a nuclear power among them) have to be economically attractive, safe enough, provided with resources and publicly acceptable. In such case they could be convinced of winning the competition with other technologies in the future But now nuclear industry is going through a period of stagnation. After the euphoria of 70th the catastrophes on TMI-2 and Chernobyl have affected very seriously on the rate of the construction of new plants and changed drastically a public perception of nuclear power problems. Later on an unacceptance of nuclear power spread and became a real obstacle for nuclear progressing in some countries. Now only in South-East Asia it can see some development in atomic area. But now a problem of nuclear energy unacceptance is seems very hard to be resolved. To change a situation and ensure the approval of nuclear power in the society it needs to shatter the myths about extraordinary danger and risks of the nuclear energy. his paper discusses the general methodology of risk analysis and the risks and benefits of future energy production. Just before end of our age a lot attention is being paid in forecasting the future and the energy production trend in particular. Typically it is declared that energy production will be doubled in next 50 years. But much concern is expressed about harmful greenhouse gases. Which way will be chosen by energy producers? In assessment the impacts of different energy scenarios a Catalog of Risk proposed by B.Cohen can be used. There an estimation of the loss of life expectancy is given for various harmful factors for USA conditions ten years ago

  3. Mindfulness-based stress reduction for veterans exposed to military sexual trauma: rationale and implementation considerations.

    Science.gov (United States)

    Gallegos, Autumn M; Cross, Wendi; Pigeon, Wilfred R

    2015-06-01

    Military sexual trauma (MST) represents a significant public health concern among military personnel and Veterans and is associated with considerable morbidity and suicide risk. It is estimated that 22% of Veteran women and 1% of Veteran men experienced sexual assault or repeated, threatening sexual harassment during their military service. Exposure to traumatic stress has detrimental effects on emotion regulation, which refers to a set of strategies used to modulate different components of emotion at different points on the trajectory of an emotional response. Mindfulness-based interventions offer approaches to health that focus on mind and body practices that can help regulate the experience and expression of difficult emotions. Mindfulness-based stress reduction (MBSR) is an evidence-based therapy shown to be effective for depression, anxiety, and post-traumatic stress disorder. This article discusses the rationale for providing MBSR to Veterans who have been exposed to MST. The article also discusses ways to facilitate implementation of this practice in the U.S. Department of Veterans Affairs health care system. We address potential barriers to care and ways to facilitate implementation at the patient, provider, organization/local, and policy levels. MBSR is likely to be an important component of a comprehensive approach to care for Veterans exposed to MST. Reprint & Copyright © 2015 Association of Military Surgeons of the U.S.

  4. Chest X ray examination of workers exposed to pneumoconiosis risk

    International Nuclear Information System (INIS)

    Indovina, P.L.; Reggiani, A.; Calicchia, A.; Nicolosi, A.

    1986-01-01

    Chest X-ray examination of workers exposed to pneumoconiosis risk: critical analysis of legal and radiation protection aspects. Chest X-ray examination is one of the most common radiological examinations practised in Italy. According to Presidential Decree 1124/65, workers exposed to risk of asbestosis and silicosis must undergo a chest radiography once a year, on occasion of the periodic medical examination. Basic requirements aimed at the radiation protection of the patient must therefore be complied with, and optimization of the chest radiography execution procedures is required. This paper illustrates the results obtained with the implementation of the NEXT programme in Italy for this kind of X-ray examination. The main objective of the NEXT programme is the optimization of radiological techniques. On the basis of the most recent publications in the field of radiation protection, a critical analysis is made of the laws in force in Italy

  5. Leukemias in the progeny of exposed parents

    International Nuclear Information System (INIS)

    Kosenko, M.M.; Gudkova, N.V.

    1996-01-01

    The purpose of this study was to assess the incidence of leukemias among the progeny of exposed parents. The parents were exposed as a result of discharge of radioactive waste from the Mayak atomic plant into the Techa river in the Southern Urals. The doses per parents gonads, ranging from 0.035 to 1.27 Sv, were due to external exposure in 1950-1956 and to incorporation of Cs-137. Nine cases with leukemia and four with lympohoma were recorded in 13.500 antenatally exposed subjects and descendants of exposed parents over the period of 1950 to 1988. The leukemia morbidity index for the progeny of exposed parents was 2.51, which virtually not statistically differ from that in control group. Refs. 7, figs. 3, tabs. 3

  6. Eryptosis in lead-exposed workers.

    Science.gov (United States)

    Aguilar-Dorado, Itzel-Citlalli; Hernández, Gerardo; Quintanar-Escorza, Martha-Angelica; Maldonado-Vega, María; Rosas-Flores, Margarita; Calderón-Salinas, José-Víctor

    2014-12-01

    Eryptosis is a physiological phenomenon in which old and damaged erythrocytes are removed from circulation. Erythrocytes incubated with lead have exhibited major eryptosis. In the present work we found evidence of high levels of eryptosis in lead exposed workers possibly via oxidation. Blood samples were taken from 40 male workers exposed to lead (mean blood lead concentration 64.8μg/dl) and non-exposed workers (4.2μg/dl). The exposure to lead produced an intoxication characterized by 88.3% less δ-aminolevulinic acid dehydratase (δALAD) activity in lead exposed workers with respect to non-lead exposed workers. An increment of oxidation in lead exposed workers was characterized by 2.4 times higher thiobarbituric acid-reactive substance (TBARS) concentration and 32.8% lower reduced/oxidized glutathione (GSH/GSSG) ratio. Oxidative stress in erythrocytes of lead exposed workers is expressed in 192% higher free calcium concentration [Ca(2+)]i and 1.6 times higher μ-calpain activity with respect to non-lead exposed workers. The adenosine triphosphate (ATP) concentration was not significantly different between the two worker groups. No externalization of phosphatidylserine (PS) was found in non-lead exposed workers (lead exposed workers showed 2.82% externalization. Lead intoxication induces eryptosis possibly through a molecular pathway that includes oxidation, depletion of reduced glutathione (GSH), increment of [Ca(2+)], μ-calpain activation and externalization of PS in erythrocytes. Identifying molecular signals that induce eryptosis in lead intoxication is necessary to understand its physiopathology and chronic complications. Copyright © 2014 Elsevier Inc. All rights reserved.

  7. Corrosion of beryllium exposed to celotex and water

    International Nuclear Information System (INIS)

    Hill, M.A.; Butt, D.P.; Lillard, R.S.

    1997-01-01

    Celotex is a commercial rigid cellulose fiberboard product primarily used in the building construction industry. Currently celotex is being used as a packing material in AL-R8 containers. Ion chromatography of celotex packing material at Lawrence Livermore National Laboratory (LLNL) has indicated that this material contains aggressive anions, including chloride, which may accelerate corrosion. It is well known that beryllium is susceptible to pitting corrosion when exposed to chloride containing environments. Levy noted pitting in beryllium at the open circuit potential when exposed to 0.1 M NaCl solution. This investigation attempts to evaluate the potential risk of accelerated beryllium corrosion from celotex and water which may occur naturally when celotex dust comes into contact with moisture from the atmosphere

  8. [Hepatotoxicity in healthy infants exposed to nevirapine during pregnancy].

    Science.gov (United States)

    Iveli, Pablo; Noguera-Julian, Antoni; Soler-Palacín, Pere; Martín-Nalda, Andrea; Rovira-Girabal, Núria; Fortuny-Guasch, Clàudia; Figueras-Nadal, Concepció

    2016-01-01

    The use of nevirapine in HIV-infected pregnant women is discouraged due to its potential to cause hepatotoxicity. There is limited information available on the toxicity in non-HIV infected newborn exposed to this drug during pregnancy. The aim of the study is to determine the extent of hepatotoxicity in the newborn exposed to nevirapine and HIV during pregnancy. A cross-sectional, observational, multicenter study was conducted on a cohort of healthy infants born to HIV-infected mothers, in whom the first determination of alanine aminotransferase (ALT), before 6weeks of age, was collected. Patients were allocated to 2groups according to exposure to nevirapine during pregnancy. Hepatotoxicity was rated according to the AIDS Table for Grading the Severity of Adult and Pediatric Adverse Events (DAIDS). This study included 160newborns from 159pregnancies (88exposed to nevirapine-based regimens and 71 exposed to protease inhibitors-based therapies). No cases of hepatotoxicity were observed according to the DAIDS Table for Grading. Two cases of ALT above normal values (2.8%; 95%CI: 0.3-9.8%) were observed in patients not exposed to nevirapine, and one case (1.1%; 95%CI: 0.0-6.1%) in the group exposed to nevirapine (P=.585). The lack of differences between groups suggests that highly active antiretroviral treatment regimens including nevirapine administered during pregnancy do not involve a higher risk of liver disease compared to other treatment combinations. Copyright © 2014 Elsevier España, S.L.U. y Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.

  9. Proposed nomination of Yucca Mountain as a potential high-level radioactive waste repository. Registration and transcript of proceedings of US Department of Energy public hearings, Las Vegas, Nevada, March 1983

    International Nuclear Information System (INIS)

    1983-01-01

    The purpose of this public hearing were: (1) to solicit comments on the nomination of Yucca Mountain for site characterization as a potential high-level radioactive waste repository; (2) to solicit issues to be included in an Environmental Assessment supporting the Department's formal nomination of that site; and (3) to solicit issues to be addressed in the Site Characterization Plan which would subsequently be issued prior to proceeding with site characterization. The public hearing utilized a panel comprising of three persons, including a chairperson, who were not employees of the Department of Energy, and who had not participated in the preparation of the proposed nomination of Yucca Mountain. This volume contains statements from 29 participants, beginning with those of the Governor of Nevada

  10. US Department of Energy public hearing for the proposed nomination of Yucca Mountain as a potential high level radioactive waste repository. Registration and transport of proceedings, Reno, Nevada - March 1983

    International Nuclear Information System (INIS)

    1983-01-01

    The purpose of this public hearing was: (1) to solicit comments on the nomination of Yucca Mountain for site characterization as a potential high-level radioactive waste repository; (2) to solicit issues to be included in an Environmental Assessment supporting the Departments' formal nomination of that site; and (3) to solicit issues to be addressed in the Site Characterization Plan which would subsequently be issued prior to proceeding with site characterization. The public hearing utilized a panel comprising of three persons including a chairperson, who were not employees of the Department of Energy, and who had not participated directly in the preparation of the proposed nomination of Yucca Mountain. This volume contains statements from 24 participants

  11. Eryptosis in lead-exposed workers

    International Nuclear Information System (INIS)

    Aguilar-Dorado, Itzel-Citlalli; Hernández, Gerardo; Quintanar-Escorza, Martha-Angelica; Maldonado-Vega, María; Rosas-Flores, Margarita; Calderón-Salinas, José-Víctor

    2014-01-01

    Eryptosis is a physiological phenomenon in which old and damaged erythrocytes are removed from circulation. Erythrocytes incubated with lead have exhibited major eryptosis. In the present work we found evidence of high levels of eryptosis in lead exposed workers possibly via oxidation. Blood samples were taken from 40 male workers exposed to lead (mean blood lead concentration 64.8 μg/dl) and non-exposed workers (4.2 μg/dl). The exposure to lead produced an intoxication characterized by 88.3% less δ-aminolevulinic acid dehydratase (δALAD) activity in lead exposed workers with respect to non-lead exposed workers. An increment of oxidation in lead exposed workers was characterized by 2.4 times higher thiobarbituric acid-reactive substance (TBARS) concentration and 32.8% lower reduced/oxidized glutathione (GSH/GSSG) ratio. Oxidative stress in erythrocytes of lead exposed workers is expressed in 192% higher free calcium concentration [Ca 2+ ] i and 1.6 times higher μ-calpain activity with respect to non-lead exposed workers. The adenosine triphosphate (ATP) concentration was not significantly different between the two worker groups. No externalization of phosphatidylserine (PS) was found in non-lead exposed workers (< 0.1%), but lead exposed workers showed 2.82% externalization. Lead intoxication induces eryptosis possibly through a molecular pathway that includes oxidation, depletion of reduced glutathione (GSH), increment of [Ca 2+ ], μ-calpain activation and externalization of PS in erythrocytes. Identifying molecular signals that induce eryptosis in lead intoxication is necessary to understand its physiopathology and chronic complications. - Graphical abstract: Fig. 1. (A) Blood lead concentration (PbB) and (B) phosphatidylserine externalization on erythrocyte membranes of non-lead exposed (□) and lead exposed workers (■). Values are mean ± SD. *Significantly different (P < 0.001). - Highlights: • Erythrocytes of lead exposed workers showed higher PS

  12. Eryptosis in lead-exposed workers

    Energy Technology Data Exchange (ETDEWEB)

    Aguilar-Dorado, Itzel-Citlalli [Biochemistry Department, Centro de Investigación y Estudios Avanzados IPN, México, DF (Mexico); Hernández, Gerardo [Section of Methodology of Science, Centro de Investigación y Estudios Avanzados IPN, México, DF (Mexico); Quintanar-Escorza, Martha-Angelica [Faculty of Medicine, UJED, Durango, DGO (Mexico); Maldonado-Vega, María [CIATEC, León, GTO (Mexico); Rosas-Flores, Margarita [Biochemistry Department, Centro de Investigación y Estudios Avanzados IPN, México, DF (Mexico); Calderón-Salinas, José-Víctor, E-mail: jcalder@cinvestav.mx [Biochemistry Department, Centro de Investigación y Estudios Avanzados IPN, México, DF (Mexico)

    2014-12-01

    Eryptosis is a physiological phenomenon in which old and damaged erythrocytes are removed from circulation. Erythrocytes incubated with lead have exhibited major eryptosis. In the present work we found evidence of high levels of eryptosis in lead exposed workers possibly via oxidation. Blood samples were taken from 40 male workers exposed to lead (mean blood lead concentration 64.8 μg/dl) and non-exposed workers (4.2 μg/dl). The exposure to lead produced an intoxication characterized by 88.3% less δ-aminolevulinic acid dehydratase (δALAD) activity in lead exposed workers with respect to non-lead exposed workers. An increment of oxidation in lead exposed workers was characterized by 2.4 times higher thiobarbituric acid-reactive substance (TBARS) concentration and 32.8% lower reduced/oxidized glutathione (GSH/GSSG) ratio. Oxidative stress in erythrocytes of lead exposed workers is expressed in 192% higher free calcium concentration [Ca{sup 2+}]{sub i} and 1.6 times higher μ-calpain activity with respect to non-lead exposed workers. The adenosine triphosphate (ATP) concentration was not significantly different between the two worker groups. No externalization of phosphatidylserine (PS) was found in non-lead exposed workers (< 0.1%), but lead exposed workers showed 2.82% externalization. Lead intoxication induces eryptosis possibly through a molecular pathway that includes oxidation, depletion of reduced glutathione (GSH), increment of [Ca{sup 2+}], μ-calpain activation and externalization of PS in erythrocytes. Identifying molecular signals that induce eryptosis in lead intoxication is necessary to understand its physiopathology and chronic complications. - Graphical abstract: Fig. 1. (A) Blood lead concentration (PbB) and (B) phosphatidylserine externalization on erythrocyte membranes of non-lead exposed (□) and lead exposed workers (■). Values are mean ± SD. *Significantly different (P < 0.001). - Highlights: • Erythrocytes of lead exposed workers

  13. Why health visiting? Examining the potential public health benefits from health visiting practice within a universal service: a narrative review of the literature.

    Science.gov (United States)

    Cowley, Sarah; Whittaker, Karen; Malone, Mary; Donetto, Sara; Grigulis, Astrida; Maben, Jill

    2015-01-01

    There is increasing international interest in universal, health promoting services for pregnancy and the first three years of life and the concept of proportionate universalism. Drawing on a narrative review of literature, this paper explores mechanisms by which such services might contribute to health improvement and reducing health inequalities. Through a narrative review of empirical literature, to identify: (1) What are the key components of health visiting practice? (2) How are they reflected in implementing the universal service/provision envisaged in the English Health Visitor Implementation Plan (HVIP)? The paper draws upon a scoping study and narrative review. We used three complementary approaches to search the widely dispersed literature: (1) broad, general search, (2) structured search, using topic-specific search terms, (3) seminal paper search. Our key inclusion criterion was information about health visiting practice. We included empirical papers from United Kingdom (UK) from 2004 to February 2012 and older seminal papers identified in search (3), identifying a total of 348 papers for inclusion. A thematic content analysis compared the older (up to 2003) with more recent research (2004 onwards). The analysis revealed health visiting practice as potentially characterized by a particular 'orientation to practice.' This embodied the values, skills and attitudes needed to deliver universal health visiting services through salutogenesis (health creation), person-centredness (human valuing) and viewing the person in situation (human ecology). Research about health visiting actions focuses on home visiting, needs assessment and parent-health visitor relationships. The detailed description of health visitors' skills, attitudes, values, and their application in practice, provides an explanation of how universal provision can potentially help to promote health and shift the social gradient of health inequalities. Identification of needs across an

  14. Modeling the potential impact of seasonal and inactive multi-aquifer wells on contaminant movement to public water-supply wells

    Science.gov (United States)

    Johnson, R.L.; Clark, B.R.; Landon, M.K.; Kauffman, L.J.; Eberts, S.M.

    2011-01-01

    Wells screened across multiple aquifers can provide pathways for the movement of surprisingly large volumes of groundwater to confined aquifers used for public water supply (PWS). Using a simple numerical model, we examine the impact of several pumping scenarios on leakage from an unconfined aquifer to a confined aquifer and conclude that a single inactive multi-aquifer well can contribute nearly 10% of total PWS well flow over a wide range of pumping rates. This leakage can occur even when the multi-aquifer well is more than a kilometer from the PWS well. The contribution from multi-aquifer wells may be greater under conditions where seasonal pumping (e.g., irrigation) creates large, widespread downward hydraulic gradients between aquifers. Under those conditions, water can continue to leak down a multi-aquifer well from an unconfined aquifer to a confined aquifer even when those multi-aquifer wells are actively pumped. An important implication is that, if an unconfined aquifer is contaminated, multi-aquifer wells can increase the vulnerability of a confined-aquifer PWS well.

  15. The properties degradation of exposed GFRP roof

    Science.gov (United States)

    Zainudin, Mohammad; Diharjo, Kuncoro; Kaavessina, Mujtahid; Setyanto, Djoko

    2018-02-01

    There is much consideration of roof selection as a protector of a building against the outside weather, such as lightweight, strong stiff, corrosion resistant and guarantee for the availability of products. Based on these considerations, glass fiber reinforced polymer (GFRP) roof is a roof which can fulfill the requirement. The objective of this research is to investigate the degradation of physical and mechanical properties of GFRP roof exposed in outside weather. This GFRP roof composite was produced using a sheet molding compound (SMC) supplied by PT Intec Persada, Tangerang, Indonesia. There are two kinds GFRP roofs evaluated in this research that are GFRP roof exposed within 7 years and new GFRP roof that has not been exposed. The GFRP roofs were cut manually for preparing the specimens for hardness test, tensile test, SEM and FTIR test. The results show that the GFRP roof exposed within 7 years had the degradation of properties compared to the new GFRP roof. The exposed GFRP roof had lower strength and hardness compared to the new GFRP roof. The SEM observation indicates that exposed GFRP roof had the debonding of fiber on the surface, and in contrast, there are no debonding of fiber in the new GFRP roof surface. It can be recommended that the exposed GFRP roof may be repaired to enhance its performance and can re-increase its properties using the coating.

  16. The Career Education Policy Project (CEPP): Connecting Educators, Policymakers, and the Public. Annual Evaluation Report. Final Report, July 1, 1975-June 30, 1976.

    Science.gov (United States)

    Siegal, Jane

    To inform and interconnect educational practitioners, knowledge-makers, policymakers, and the consuming public around the issues and potential of career education, the Career Education Policy Project (CEEP) collaborated with several existing programs to expose out-of-town leaders of the career education movement to the federal policymaking…

  17. 210Pb and 210Po concentrations in the Venice lagoon ecosystem (Italy) and the potential radiological impact to the local public and environment

    International Nuclear Information System (INIS)

    Guogang Jia; Belli, M.; Sansone, U.; Rosamilia, S.; Blasi, M.

    2003-01-01

    In order to evaluate the possible radiological impact to the local public and environment from a phosphogypsum stockpile, 210 Po and 210 Pb concentrations in river water, lagoon water, suspended matter, superficial sediment, algae and bivalves samples collected in Venice lagoon area have been investigated. The results show that the mean 210 Po and 210 Pb concentrations in river water are 1.42 ± 0.36 mBq x l -1 and 1.46 ± 0.39 mBq x l -1 with a mean 210 Po/ 210 Pb ratio of 0.98 ± 0.17 and about 60% of them are associated with the particulate; 210 Po and 210 Pb contribution from the phosphogypsum stockpile to the river water is negligible. Higher 210 Po (2.61-5.67 mBq x l -1 ) and 210 Pb (1.31-3.62 mBq x l -1 ) concentrations in the lagoon waters have been observed if compared with the literature values. About 60% of 210 Po and 210 Pb are found in the soluble form with a mean 210 Po/ 210 Pb ratio of 1.79 ± 1.47. 210 Po and 210 Pb concentrations in 28 out 37 sediment samples ranged from 26 to 45 Bq x kg -1 (dry weight), only 9 sediments with 210 Po and 210 Pb concentrations greater than 45 Bq x kg -1 are found and most of them are located 1-4 km near the phosphogypsum stockpile. The elevated 210 Po and 210 Pb concentrations in the sediments may be due to the contamination from the phosphogypsum stockpile. The mean 210 Po/ 210 Pb ratio (0.986 ± 0.049) in the sediments shows that 210 Po and 210 Pb exist in nearly secular equilibrium. 210 Po and 210 Pb concentrations in algae vary with different species. The mean 210 Po and 210 Pb concentrations in Gracilaria compress and Ulva laetevirens which show a similar behavior, are 3.18 ± 1.23 Bq x kg -1 and 2.42 ± 1.26 Bq x kg -1 (fresh weight), respectively, with a mean 210 Po/ 210 Pb ratio of 1.45 ± 0.34. The mean concentration factors with respect to the filtered water are 1096 ± 424 for 210 Po and 1299 ± 680 for 210 Pb. The mean 210 Po and 210 Pb concentrations in the soft part of Mytilus edulis are 23.2 ± 9.7 Bq

  18. Influence of Some Pesticides on Humoral and Cellular Immunity of Exposed Workers in Pesticides Industries

    International Nuclear Information System (INIS)

    Osely, E.Sh.M.

    2010-01-01

    Pesticide poisoning is a major public health problem in developing countries. In most of these countries organophosphate pesticides constitute the most widely used pesticides. The main toxicity of OPs is neurotoxicity, which is caused by the inhibition of acetylcholinesterase. OPs also affect the immune response, including effects on cellular and humoral immunity. Our study examined the effect of organophosphorus compounds on humoral and cellular immunity of exposed workers in pesticides industries. The study was conducted into 40 subjects. They were 2 groups; 20 exposed workers from Gharbeia and Kafr Elsheikh at 2008 and 2009 and 20 unexposed individuals as a control group at the same period of time. We examined some immune parameters; pseudocholinesterase, WBCs count, CD4%, CD8%, CD4/CD8, CD56%, Interleukin 2, IgG and IgM. Also we take history and clinical examination for them. We reported a highly significant decrease in pseudo cholinesterase level among the exposed group in comparison to the control group, highly significant increase in percentage of CD8 in the exposed group in comparison to control group, highly significant decrease in CD4 / CD8 ratio in the exposed group in comparison to control group, highly significant decrease in percentage of CD56 in the exposed group in comparison to control group and a highly significant increase in IgG level in the exposed group in comparison to control group. On the other hand, we reported no significant change in white blood cells count between the exposed and control groups, no significant change in percentage of CD4 among the exposed and control group, no significant change in Interleukin 2 level among the exposed and control group and no significant change in IgM level among the exposed and control group. We concluded that pesticides extensively affect the humoral and cellular immune system of occupationally exposed workers.

  19. Drug and Alcohol Exposed Children: Implications for Special Education for Students Identified as Behaviorally Disordered.

    Science.gov (United States)

    Bauer, Anne M.

    1991-01-01

    This article reviews the literature on children prenatally exposed to drugs and alcohol, the potential impact on the educational and social services systems, and implications for programing for children identified as behaviorally disordered. (Author/JDD)

  20. Public lighting.

    NARCIS (Netherlands)

    Schreuder, D.A.

    1986-01-01

    The function of public lighting and the relationship between public lighting and accidents are considered briefly as aspects of effective countermeasures. Research needs and recent developments in installation and operational described. Public lighting is an efficient accident countermeasure, but

  1. Disposal of tritium-exposed metal hydrides

    International Nuclear Information System (INIS)

    Nobile, A.; Motyka, T.

    1991-01-01

    A plan has been established for disposal of tritium-exposed metal hydrides used in Savannah River Site (SRS) tritium production or Materials Test Facility (MTF) R ampersand D operations. The recommended plan assumes that the first tritium-exposed metal hydrides will be disposed of after startup of the Solid Waste Disposal Facility (SWDF) Expansion Project in 1992, and thus the plan is consistent with the new disposal requiremkents that will be in effect for the SWDF Expansion Project. Process beds containing tritium-exposed metal hydride powder will be disposed of without removal of the powder from the bed; however, disposal of tritium-exposed metal hydride powder that has been removed from its process vessel is also addressed

  2. "And they told two friends...and so on": RJ Reynolds' viral marketing of Eclipse and its potential to mislead the public.

    Science.gov (United States)

    Anderson, S J; Ling, P M

    2008-08-01

    To explore viral marketing strategies for Eclipse cigarettes used by the RJ Reynolds Company (Winston-Salem, North Carolina, USA). Analysis of previously secret tobacco industry documents and multimedia materials. The failure of RJ Reynolds' (RJR) 1988 "smokeless" cigarette, Premier, was in part due to widespread bad word of mouth about the product's flavour, quality and difficulty of use. In 1994 RJR introduced an updated version of Premier, the ostensibly "reduced risk" Eclipse cigarette. RJR developed viral marketing channels to promote Eclipse using (1) exploratory interviews to motivate consumers to spread the word about Eclipse prior to market release, (2) promotional videos featuring positive feedback from test group participants to portray majority consensus among triers, (3) "Tupperware"-like parties for Eclipse where participants received samples to pass around in their social circles and (4) the Eclipse website's bulletin board as a forum for potential users to discuss the brand in their own words. These strategies targeted the brand's likeliest adopters, recruited informal and credible representatives of the product unaffiliated with RJR, and controlled the information spread about the product. Viral marketing techniques may be particularly useful to promote new tobacco products such as Eclipse that have limited appeal and need a highly motivated audience of early adopters and acceptors. Such techniques help evade the mass rejection that could follow mass promotion, circumvent marketing restrictions, and allow tobacco companies to benefit from health claims made by consumers. Cigarette manufacturers must be held accountable for perceived health benefits encouraged by all promotional activities including viral marketing.

  3. Exposing Latent Information in Folksonomies for Reasoning

    Science.gov (United States)

    2010-01-14

    1.73 $.") http://www.w3.org/2006/07/SWD/ SKOS /reference/20081001/ Spiteri, L.F. (2007) "The structure and form of folksonomy tags: The road to the...Exposing Latent Information in Folksonomies for Reasoning January 14, 2010 Sponsored by Defense Advanced Research Projects Agency (DOD...DATES COVERED (From - To! 4/14/2009-12/23/2009 4. TITLE AND SUBTITLE Exposing Latent Information in Folksonomies for Reasoning Sa. CONTRACT

  4. El potencial de espacios públicos y patrimonios edificados en barrios y vecindades de la Comuna de Independencia. / The potential of public spaces and architectural heritage in neighborhoods of the Commune of Independence.

    Directory of Open Access Journals (Sweden)

    Pavez Reyes, María Isabel

    2004-12-01

    Full Text Available Se indaga en el espacio urbano intersticial de la Comuna de Independencia, Santiago de Chile, el potencial de desarrollo de los espacios públicos y semi-públicos, para colaborar a la definición de acciones para la conservación, reconstrucción, complemento, reinstauración o instauración de estos en el marco de un planeamiento y diseño de espacios públicos, y regularización de predios y edificios de su entorno más comprensivo y sin derroche de recursos en un área histórica pericentral metropolitana que desea atraer nueva población residente./In this article there is an exploration of what is the state of unused spaces in Independencia (Municipality in Santiago Chile and what are the potentialities in the development of public and semi public spaces as a collaboration towards the conservation, reconstruction, complementing, restoration of such spaces as part of a plan to design public spaces, regularization of the sites and buildings, that is more sensitive and less expensive and its goal is to draw new residents to this historical area in the metropolitan peri center.

  5. Reaching Outside the Comfort Zone: Realising the FCTC's Potential for Public Health Governance and Regulation in the European Union Comment on "The Legal Strength of International Health Instruments - What It Brings to Global Health Governance?"

    Science.gov (United States)

    Berteletti, Florence

    2017-09-13

    In their paper, Nikogosian and Kickbusch show how the effects of the adoption by the World Health Organization (WHO) of the Framework Convention on Tobacco Control (WHO FCTC) and its first Protocol extend beyond tobacco control and contribute to public health governance more broadly, by revealing new processes, institutions and instruments. While there are certainly good reasons to be optimistic about the impact of these instruments in the public health sphere, the experience of the FCTC's implementation in the context of the European Union (EU) shows that further efforts are still necessary for its full potential to be realised. Indeed, one of the main hurdles to the FCTC's success so far has been the difficulty in developing and maintaining comprehensive multisectoral measures and involving sectors beyond the sphere of public health. © 2018 The Author(s); Published by Kerman University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

  6. Medical care for occupational exposed personnel by authorized physicians; Arbeitsmedizinische Betreuung beruflich strahlenexponierter Personen durch ermaechtigte Aerzte

    Energy Technology Data Exchange (ETDEWEB)

    List, Volker [KIT - Karlsruher Institut fuer Technologie Medizinische Dienste, Eggenstein-Leopoldshafen (Germany). Liaison Institute der Weltgesundheitsorganisation (WHO)

    2017-07-01

    Since 2009 new scientific results and respective publications few changes in the legal regulations concerning the medical care for exposed occupational personnel occurred. These changes include the careful attention of ethical aspects and the efficiency control of radiation protection measures. In Switzerland the medical surveillance of occupational exposed persons has been terminated.

  7. Mexican unpasteurised fresh cheeses are contaminated with Salmonella spp., non-O157 Shiga toxin producing Escherichia coli and potential uropathogenic E. coli strains: A public health risk.

    Science.gov (United States)

    Guzman-Hernandez, Rosa; Contreras-Rodriguez, Araceli; Hernandez-Velez, Rosa; Perez-Martinez, Iza; Lopez-Merino, Ahide; Zaidi, Mussaret B; Estrada-Garcia, Teresa

    2016-11-21

    Fresh cheeses are a main garnish of Mexican food. Consumption of artisanal fresh cheeses is very common and most of them are made from unpasteurised cow milk. A total of 52 fresh unpasteurised cheeses of five different types were purchased from a variety of suppliers from Tabasco, Mexico. Using the most probable number method, 67% and 63% of samples were positive for faecal coliforms and E. coli, respectively; revealing their low microbiological quality. General hygienic conditions and practices of traditional cheese manufacturers were poor; most establishments had unclean cement floors, all lacked windows and doors screens, and none of the food-handlers wore aprons, surgical masks or bouffant caps. After analysing all E. coli isolates (121 strains) for the presence of 26 virulence genes, results showed that 9 (17%) samples were contaminated with diarrheagenic E. coli strains, 8 harboured non-O157 Shiga toxin producing E. coli (STEC), and one sample contained both STEC and diffusely adherent E. coli strains. All STEC strains carried the stx1 gene. Potential uropathogenic E. coli (UPEC) strains were isolated from 15 (29%) samples; the most frequent gene combination was fimA-agn43. Two samples were contaminated with Salmonella. The results demonstrated that unpasteurised fresh cheeses produced in Tabasco are of poor microbiological quality and may frequently harbour foodborne pathogens. Food safety authorities in Mexico need to conduct more rigorous surveillance of fresh cheeses. Furthermore, simple and inexpensive measures as establishing programs emphasizing good hand milking practices and hygienic manufacturing procedures may have a major effect on improving the microbiological quality of these food items. Copyright © 2016 Elsevier B.V. All rights reserved.

  8. “And they told two friends…and so on”: RJ Reynolds’ viral marketing of Eclipse and its potential to mislead the public

    Science.gov (United States)

    Anderson, S J; Ling, P M

    2010-01-01

    Objective To explore viral marketing strategies for Eclipse cigarettes used by the RJ Reynolds Company (Winston-Salem, North Carolina, USA). Methods Analysis of previously secret tobacco industry documents and multimedia materials. Results The failure of RJ Reynolds’ (RJR) 1988 “smokeless” cigarette, Premier, was in part due to widespread bad word of mouth about the product’s flavour, quality and difficulty of use. In 1994 RJR introduced an updated version of Premier, the ostensibly “reduced risk” Eclipse cigarette. RJR developed viral marketing channels to promote Eclipse using (1) exploratory interviews to motivate consumers to spread the word about Eclipse prior to market release, (2) promotional videos featuring positive feedback from test group participants to portray majority consensus among triers, (3) “Tupperware”-like parties for Eclipse where participants received samples to pass around in their social circles and (4) the Eclipse website’s bulletin board as a forum for potential users to discuss the brand in their own words. These strategies targeted the brand’s likeliest adopters, recruited informal and credible representatives of the product unaffiliated with RJR, and controlled the information spread about the product. Conclusions Viral marketing techniques may be particularly useful to promote new tobacco products such as Eclipse that have limited appeal and need a highly motivated audience of early adopters and acceptors. Such techniques help evade the mass rejection that could follow mass promotion, circumvent marketing restrictions, and allow tobacco companies to benefit from health claims made by consumers. Cigarette manufacturers must be held accountable for perceived health benefits encouraged by all promotional activities including viral marketing. PMID:18332064

  9. Evaluation of radiation protection educational level of professional exposed workers

    International Nuclear Information System (INIS)

    Marinkovic, O.; Krstev, S.; Jovanovic, S.

    2006-01-01

    Full text: Serbia and Montenegro legislation concerning with radiation protection was upgrading after publication ICRP- 60 and B.S.S., No.115. Present Law on the Protection against Ionizing Radiation is in force from 1996. Among quite new issues in radiation protection regulations there was article relate to obligatory refresher training. Due to adverse political and economic situation through many years radiation protection regulations were not fulfill completely. The aim of this investigation was to get real view to education level of professional exposed workers. In Serbia and Montenegro the most of ionizing radiation sources are in medical use and the most exposed workers are radiographers and radiologists. The test was passed by 200 radiographers and 50 radiologists. Main groups of questions were: Radiation protection and safety; difference between safety and security; legislation: law and regulations; incidents, accidents and operational failures: recording, learning. Usually, knowledge from school pales. New quantities (as ambient and personal dose equivalent) are mostly unknown. It is easier to understand the real difference between safety and security than to understand linguistic differences. Discussing regulations workers are more interesting in syndicate regulations than radiation protection ones. Operational failures and incidents are hidden. Better to say: nobody dare to speak about them. The results imposed conclusion that regulatory body has to pay more attention to upraise safety culture and radiation protection education level of professional exposed workers. (authors)

  10. TECHNICAL REPORT ON TECHNOLOGICALLY ENHANCED NATURALLY OCCURRING RADIOACTIVE MATERIALS FROM URANIUM MINING, VOLUME II: INVESTIGATION OF POTENTIAL HEALTH, GEOGRAPHIC, AND ENVIRONMENTAL ISSUES OF ABANDONED URANIUM MINES

    Science.gov (United States)

    Volume II investigates the potential radiogenic risks from abandoned uranium mines and evaluates which may pose the greatest hazards to members of the public and to the environment. The intent of this report is to identify who may be most likely to be exposed to wastes at small a...

  11. Neurobehavioral assessment of rats exposed to pristine polystyrene nanoplastics upon oral exposure.

    Science.gov (United States)

    Rafiee, Mohammad; Dargahi, Leila; Eslami, Akbar; Beirami, Elmira; Jahangiri-Rad, Mahsa; Sabour, Siamak; Amereh, Fatemeh

    2018-02-01

    The increasing use of plastics has raised concerns about pollution of freshwater by these polymeric materials. Knowledge about their potential effects on environmental and public health is limited. Recent publications have suggested that the degradation of plastics will result in the release of nano-sized plastic particles to the environment. Therefore, it is of utmost importance to gain knowledge about whether and how nanoplastics affect living organisms. The present study aimed to analyse potential neurobehavioral effects of polystyrene nanoparticles (PS-NPs) after long-term exposure on rat. Potential effects of PS-NPs were investigated using four test dosages (1, 3, 6, and 10 mg PS-NPs/kg of body weight/day) administrated orally with adult Wistar male rats for five weeks. Neurobehavioral tests were chosen to assess a variety of behavioral domains. Particle diameters in test suspensions were determined through dynamic light scattering and showed an average hydrodynamic diameter of approximately 38.92 nm. No statistically significant behavioral effects were observed in all tests performed (p > 0.05). In the elevated plus maze, PS-NPs-exposed rats showed greater number of entries into open arms compared to controls. Also, PS-NPs had no significant influence on body weight of animals. Taking into account the subtle and transient nature of neurobehavioral consequences, however, these results underline the possibility of even pristine plastic nanoparticles to induce behavioral alteration in the rest of the food web, including for marine biota and humans. Indeed even though studied neurobehavioral effects in our study was not statistically significant, the observed subtle effects may be clinically considerable. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. Mental health interventions for children exposed to disasters and terrorism.

    Science.gov (United States)

    Pfefferbaum, Betty; Newman, Elana; Nelson, Summer D

    2014-02-01

    The purpose of this review is to describe interventions used with children who are exposed to disasters and terrorism and to present information about the potential benefits of these interventions. A literature search conducted in January 2013 using relevant databases and literature known to the authors that was not generated by the search yielded a total of 85 studies appropriate for review. Intervention approaches used with children exposed to disasters and terrorism included preparedness interventions, psychological first aid, psychological debriefing, psychoeducation, cognitive behavioral techniques, exposure and narrative techniques, eye movement desensitization and reprocessing, and traumatic grief interventions. The investigation of these interventions is complex, and studies varied in methodological rigor (e.g., sample size, the use of control groups, outcomes measured). Given the limitations in the currently available empirical information, this review integrates the literature, draws tentative conclusions about the current state of knowledge, and suggests future directions for study.

  13. Upgrade and Design of Coastal Structures Exposed to Climate Changes

    DEFF Research Database (Denmark)

    Nørgaard, Jørgen Quvang Harck

    This thesis “Upgrade and Design of Coastal Structures Exposed to Climate Changes” evaluates the performance of existing types of structures when exposed to climate changes. This includes also the potential of using cost‐sharing multipurpose structures for protection against the effects of future...... climate changes. The thesis consists of three parts. The first part evaluates the performance of existing design formulae for estimation of wave actions on structures, especially in shallow water since these structures are most vulnerable to the rising sea water levels caused by climate changes. Existing...... of coastal protection structures, which are extended to a wider range of wave conditions, and which can be used to more accurately estimate the influence from climate changes. In the second part of the thesis, the extended and modified formulae are used in case studies to evaluate the influence from climate...

  14. Upgrade and Design of Coastal Structures Exposed to Climate Changes

    DEFF Research Database (Denmark)

    Nørgaard, Jørgen Quvang Harck

    This thesis "Upgrade and Design of Coastal Structures Exposed to Climate Changes" evaluates the performance of existing types of structures when exposed to climate changes. This includes also the potential of using cost‐sharing multipurpose structures for protection against the effects of future...... climate changes. The thesis consists of three parts. The first part evaluates the performance of existing design formulae for estimation of wave actions on structures, especially in shallow water since these structures are most vulnerable to the rising sea water levels caused by climate changes. Existing...... of coastal protection structures, which are extended to a wider range of wave conditions, and which can be used to more accurately estimate the influence from climate changes. In the second part of the thesis, the extended and modified formulae are used in case studies to evaluate the influence from climate...

  15. Conditions of the potential for commercialization of the patent: the implementation of a technology public offering system technology at CNEN; Condicionantes do potencial de exploracao comercial da patente: a implantacao de um sistema de oferta publica de tecnologia na CNEN

    Energy Technology Data Exchange (ETDEWEB)

    Archila, Daniela Lima Cerqueira

    2015-07-01

    This dissertation identifies the main factors which represent the conditions for the potential commercialization of patents aiming at the implementation of a system for technology public offering at CNEN as a strategy for creating licensing opportunities to the industrial sector. The method applied refers to an exploratory case study of a patented technology selected from a sample of CNEN's patent portfolio in the biopharmaceutical sector. The case study comprehends a field research of interviews conducted with two specialists in technology and innovation management, one researcher from CNEN and a biopharmaceutical company. The results show that among the nineteen main factors - related to technology, market, business and Science and Technology Organization (STO) - the market dynamics, the potential applications of the technology and an abstract of its main benefits compared to existing technologies are the major relevant information for each technology to be included in the public offering system. Other results indicate that the evaluation of such factors may be conducted by competent professionals to bring less uncertainty and risk to the early-stage of the innovation process, as well as enhance the potential interest of a company in the technology. On the other hand, the latter requires innovation capabilities to move the technology forward – additional R&D, scale-up, manufacturing and marketing - whilst the STO needs a entrepreneurial culture that mitigates its obstacles, creates more positive solutions for its routines and processes and gives sustainability to its Technology Transfer Office (TTO) through valuing its personnel in the long term. Finally, emphasis on technological partnerships with companies can be a motivating feature for directing the STO's patent strategy to the creation of proprietary technological platforms that reflect problems experienced by the commercial environment, as well as the development of this strategic patent

  16. Public health and Plowshare

    Energy Technology Data Exchange (ETDEWEB)

    Terrill, Jr, J G [Consumer Protection and Environmental Health Service, U.S. PubIic Health Service, Washington, DC (United States)

    1969-07-01

    The protection of public health and safety is a principal area of concern in any application of nuclear energy. A health and safety analysis must be conducted and reviewed by appropriate agencies and the final results made available to interested agencies and groups, both public and private, prior to the application. This is especially important for the Plowshare Program - the peaceful uses of nuclear explosives - where the public is to be the ultimate beneficiary. Because public health must be a primary concern in the Plowshare Program, it is essential that the potential risk be weighed against the expected benefits to the public. Public health agencies must play an increasingly important role in the planning and operational stages of the peaceful applications of nuclear explosives and in the final stage of consumer use of Plowshare-generated products. There are many long term and long distance ramifications of the Plowshare Program, such a the potential radiological contamination of consumer products that may reach the consumer at long times after the event or at great distances from the site of the event. Criteria for evaluating public exposure to radiation from these products need to be developed based on sound scientific research. Standards for radioactivity in consumer products must be developed in relation to potential exposure of the public. Above all, a clear benefit to the public with a minimum of risk must be shown. The major purpose of this Symposium on the Public Health Aspects of Peaceful Uses of Nuclear-Explosives is to focus attention on the health and safety aspects, present the results of safety analyses accomplished to date and other information necessary to an understanding of the public health aspects, and to identify areas where additional research is required. A general overview of the total symposium content is presented with emphasis on the relationship of the topics to public health. (author)

  17. Public health and Plowshare

    International Nuclear Information System (INIS)

    Terrill, J.G. Jr.

    1969-01-01

    The protection of public health and safety is a principal area of concern in any application of nuclear energy. A health and safety analysis must be conducted and reviewed by appropriate agencies and the final results made available to interested agencies and groups, both public and private, prior to the application. This is especially important for the Plowshare Program - the peaceful uses of nuclear explosives - where the public is to be the ultimate beneficiary. Because public health must be a primary concern in the Plowshare Program, it is essential that the potential risk be weighed against the expected benefits to the public. Public health agencies must play an increasingly important role in the planning and operational stages of the peaceful applications of nuclear explosives and in the final stage of consumer use of Plowshare-generated products. There are many long term and long distance ramifications of the Plowshare Program, such a the potential radiological contamination of consumer products that may reach the consumer at long times after the event or at great distances from the site of the event. Criteria for evaluating public exposure to radiation from these products need to be developed based on sound scientific research. Standards for radioactivity in consumer products must be developed in relation to potential exposure of the public. Above all, a clear benefit to the public with a minimum of risk must be shown. The major purpose of this Symposium on the Public Health Aspects of Peaceful Uses of Nuclear-Explosives is to focus attention on the health and safety aspects, present the results of safety analyses accomplished to date and other information necessary to an understanding of the public health aspects, and to identify areas where additional research is required. A general overview of the total symposium content is presented with emphasis on the relationship of the topics to public health. (author)

  18. Proximally exposed A-bomb survivors. 2

    International Nuclear Information System (INIS)

    Kamada, Nanao

    1992-01-01

    Methods for observing chromosomes can be chronologically divided into the era of non-differential staining technique (1962-1975) and the era of differential staining method (since 1976). This paper reviews the literature of chromosomal aberrations in bone marrow cells found in the two eras. Findings during the era of 1962-1975 include the frequency of chromosomal aberrations in bone marrow cells, comparison of chromosomal aberrations in bone marrow cells and T lymphocytes, and annual variation of chromosomal aberrations. The frequency of chromosomal aberrations was high in proximally exposed A-bomb survivors (90.5% and 52.6% in A-bomb survivors exposed within 500 m and at 501-1,000 m, respectively); on the contrary, it was low in those exposed far from 1,000 m (6.2% or less). The frequency of chromosomal aberrations in bone marrow cells was lower than that in T lymphocytes (21.5% vs 27.1% in those exposed within 500 m and 14.1% vs 23% in those exposed at 501-1,000 m). Annual analysis for chromosomal aberrations has shown the somewhat dependence upon medullary hematopoiesis and virus infection. The advent of differential staining technique since 1976 has made it possible to clarify the type of chromosomal aberrations and site of breakage. Of 710 bone marrow cells taken from 13 A-bomb survivors exposed within 1,000 m, 121 cells (from 11 A-bomb survivors) exhibited chromosomal aberrations. In differential staining analysis, all 121 cells but one were found to be of stable type, such as translocation and inversion. Furthermore, the site of breakage was found to be non-randomly distributed. Analysis of chromosomal aberrations in bone marrow cells has advantages of reflecting dynamic condition of these cells and determining gradual progression into leukemia. (N.K.)

  19. Physiological and behavioral responses of poultry exposed to gas-filled high expansion foam.

    Science.gov (United States)

    McKeegan, D E F; Reimert, H G M; Hindle, V A; Boulcott, P; Sparrey, J M; Wathes, C M; Demmers, T G M; Gerritzen, M A

    2013-05-01

    Disease control measures require poultry to be killed on farms to minimize the risk of disease being transmitted to other poultry and, in some cases, to protect public health. We assessed the welfare implications for poultry of the use of high-expansion gas-filled foam as a potentially humane, emergency killing method. In laboratory trials, broiler chickens, adult laying hens, ducks, and turkeys were exposed to air-, N2-, or CO2-filled high expansion foam (expansion ratio 300:1) under standardized conditions. Birds were equipped with sensors to measure cardiac and brain activity, and measurements of oxygen concentration in the foam were carried out. Initial behavioral responses to foam were not pronounced but included headshakes and brief bouts of wing flapping. Both N2- and CO2-filled foam rapidly induced ataxia/loss of posture and vigorous wing flapping in all species, characteristic of anoxic death. Immersion in air-filled, high expansion foam had little effect on physiology or behavior. Physiological responses to both N2- and CO2-filled foam were characterized by a pronounced bradyarrythymia and a series of consistent changes in the appearance of the electroencephalogram. These were used to determine an unequivocal time to loss of consciousness in relation to submersion. Mean time to loss of consciousness was 30 s in hens and 18 s in broilers exposed to N2-filled foam, and 16 s in broilers, 1 s in ducks, and 15 s in turkeys exposed to CO2-filled foam. Euthanasia achieved with anoxic foam was particularly rapid, which is explained by the very low oxygen concentrations (below 1%) inside the foam. Physiological observations and postmortem examination showed that the mode of action of high expansion, gas-filled foam is anoxia, not occlusion of the airway. These trials provide proof-of-principle that submersion in gas-filled, high expansion foam provides a rapid and highly effective method of euthanasia, which may have potential to provide humane emergency killing

  20. Biomarkers of genetic damage in human populations exposed to pesticides

    International Nuclear Information System (INIS)

    Aiassa, Delia; Manas, Fernando; Bosch, Beatriz; Gentile, Natalia; Bernardi, Natali; Gorla, Nora

    2012-01-01

    The effect of pesticides on human, animal and environmental health has been cause of concern in the scientific community for a long time. Numerous studies have reported that pesticides are not harmless and that their use can lead to harmful biological effects in the medium and long term, in exposed human and animals, and their offspring. The importance of early detection of genetic damage is that it allows us to take the necessary measures to reduce or eliminate the exposure to the deleterious agent when damage is still reversible, and thus to prevent and to diminish the risk of developing tumors or other alterations. In this paper we reviewed the main concepts in the field, the usefulness of genotoxicity studies and we compiled studies performed during the last twenty years on genetic monitoring of people occupationally exposed to pesticides. we think that genotoxicity tests, including that include chromosomal aberrations, micronucleus, sister chromatid exchanges and comet assays, should be considered as essential tools in the implementation of complete medical supervision for people exposed to potential environmental pollutants, particularly for those living in the same place as others who were others have already developed some type of malignancy. This action is particularly important at early stages to prevent the occurrence of tumors, especially from environmental origins.

  1. Public Schools

    Data.gov (United States)

    Department of Homeland Security — This Public Schools feature dataset is composed of all Public elementary and secondary education in the United States as defined by the Common Core of Data, National...

  2. Exposing the Mathematical Wizard: Approximating Trigonometric Functions

    Science.gov (United States)

    Gordon, Sheldon P.

    2011-01-01

    For almost all students, what happens when they push buttons on their calculators is essentially magic, and the techniques used are seemingly pure wizardry. In this article, the author draws back the curtain to expose some of the mathematics behind computational wizardry and introduces some fundamental ideas that are accessible to precalculus…

  3. Exposing Library Services with AngularJS

    OpenAIRE

    Jakob Voß; Moritz Horn

    2014-01-01

    This article provides an introduction to the JavaScript framework AngularJS and specific AngularJS modules for accessing library services. It shows how information such as search suggestions, additional links, and availability can be embedded in any website. The ease of reuse may encourage more libraries to expose their services via standard APIs to allow usage in different contexts.

  4. Expose Mechanical Engineering Students to Biomechanics Topics

    Science.gov (United States)

    Shen, Hui

    2011-01-01

    To adapt the focus of engineering education to emerging new industries and technologies nationwide and in the local area, a biomechanics module has been developed and incorporated into a mechanical engineering technical elective course to expose mechanical engineering students at ONU (Ohio Northern University) to the biomedical engineering topics.…

  5. Stabilizer for seismically exposed bridge cranes

    International Nuclear Information System (INIS)

    Engelke, M.; Kuhr, H.

    1982-01-01

    The invention concerns a stabilizer for seismically exposed bridge cranes in reactor buildings. The trolley and the crane bridge are fitted with the stabilizer consisting of a bipartite safety catch which is connected with a joint and able to take up the vertical loads during an earthquake. This stabilizer is suitable for all kinds of bridge cranes operated in seismically active regions

  6. Dose coefficients for individual occupationally exposed

    International Nuclear Information System (INIS)

    2005-11-01

    This Regulation refers to the requirements of the Regulation CNEN-NN.3.01, 'Basic Act of Radiological Protection', aiming its application to the dose calculation, with purposes of conformity verification with limits and restrictions of doses and level of reference for individual occupationally exposed, according to the express in its section 5

  7. Posttraumatic Stress, Coping Flexibility, and Risky Drinking Among Trauma-Exposed Male and Female College Students: The Mediating Effect of Delay of Gratification.

    Science.gov (United States)

    Boyraz, Güler; Cherry, Megan L; Cherry, Marcus A; Aarstad-Martin, Samantha; Cloud, Cody; Shamp, Lindsey M

    2018-02-23

    The co-occurence of posttraumatic stress (PTS) and risky drinking has been demonstrated in diverse populations, including college students. However, the mechanisms underlying this co-occurrence, as well as the protective factors that may reduce risky drinking among trauma-exposed college students have yet to be fully understood in the literature. The present study builds upon self-regulation theories and previous empirical work to determine whether the effects of PTS and coping flexibility on risky drinking were mediated by delay of gratification among trauma-exposed college students. In addition, the potential moderating effect of gender on these relationships was examined. Participants included 624 trauma-exposed college students (68.4% female) attending a public university in the southeast region of the United States. Data were collected through an online survey. The hypothesized model was examined using a multigroup structural equation modeling approach. As hypothesized, PTS had a significant, positive indirect effect on risky drinking through delay of gratification; however, the effect of PTS on delay of gratification was stronger for males than for females. Results also indicated that the indirect effect of coping flexibility on risky drinking through delay of gratification was significant and negative for males and females. Conclusions/Importance: The findings of this study suggest that delay of gratification might be an important mechanism underlying the co-occurrence of PTS and risky drinking. In addition, our results highlight the potential benefits of coping flexibility for college students coping with PTS.

  8. Public acceptability

    International Nuclear Information System (INIS)

    Bolter, H.E.

    1989-01-01

    An urgent need to rebuild public confidence after an incident attracting widespread adverse publicity led to the development by British Nuclear Fuels plc of a completely new approach to public relations. The Company's experience suggests that impressions count more than sheer information, provided the impressions have a firm base in reality. (author)

  9. 'Cut in two', Part 1: Exposing the Seam in Q 12:42−46

    African Journals Online (AJOL)

    2015-06-22

    Jun 22, 2015 ... 'Cut in two', Part 1: Exposing the Seam in Q 12:42−46. This publication ..... on as normal for everyone except the appointed slave. This .... Greek and English with parallels from the Gospels of Mark and Thomas, Fortress,.

  10. Disconnect Between Public Sector Management System and ...

    African Journals Online (AJOL)

    three regional governments, this article exposes how public sector management system (public finance and human resource management system) determines decentralization outcomes. It contends that outcomes of decentralization reforms are shaped not only by political and economic factors, as suggested in the ...

  11. Public health communications for safe motherhood.

    Science.gov (United States)

    Kessel, E

    1994-03-30

    Public health communication aims to influence health practices of large populations, including maternal health care providers (traditional birth attendants, (TBAs), nurse-midwives, other indigenous practitioners, and physicians). A quality assurance process is needed to give public sector health providers feedback. Computerized record keeping is needing for quality assurance of maternal health programs. The Indian Rural Medical Association has trained more than 20,000 rural indigenous practitioners in West Bengal. Training of TBAs is expensive and rarely successful. However, trained health professional leading group discussions of TBAs is successful at teaching them about correct maternity care. Health education messages integrated into popular songs and drama is a way to reach large illiterate audiences. Even though a few donor agencies and governments provide time and technical assistance to take advantage of the mass media as a means to communicate health messages, the private sector has most of the potential. Commercial advertisements pay for Video on Wheels, which, with 100 medium-sized trucks each fitted with a 100-inch screen, plays movies for rural citizens of India. They are exposed to public and family planning messages. Jain Satellite Television (JST) broadcasts 24 hours a day and plans to broadcast programs on development, health and family planning, women's issues, and continuing education for all health care providers (physicians, nurses, TBAs, community workers, and indigenous practitioners). JST and the International Federation for Family Health plan to telecast courses as part of an Open University of Health Sciences.

  12. Attitude change in youths after being exposed to different road safety interventions in two Mexican cities.

    Science.gov (United States)

    Híjar, Martha; Pérez-Núñez, Ricardo; Santoyo-Castillo, Dzoara; Lunnen, Jeffrey C; Chandran, Aruna; Celis, Alfredo; Carmona-Lozano, Socorro

    2013-12-01

    To assess the reach of three different types of road safety interventions (social marketing, education and law enforcement) implemented as part of the Iniciativa Mexicana de Seguridad Vial y Prevención de Lesiones en el Tránsito (Mexican Initiative for Road Safety and the Prevention of Road Traffic Injuries) among youth in two Mexican cities (Guadalajara-Zapopan, Jalisco and León, Guanajuato), and to examine students' self-reported attitude change after being exposed to these interventions. A cross-sectional design was utilized to evaluate the reach of the city-wide interventions among a random sample of public and private high school and college students from October to December 2011. A total of 5,114 students completed a self-administered questionnaire. In both cities, students reported a greater exposure to social marketing (73% in Guadalajara-Zapopan and 64% in León) as compared to educational interventions (29.3% in León and 21.6% in Guadalajara-Zapopan) and law enforcement activities (~12% in both). Among respondents, self-reported attitude change was higher after being exposed to educational interventions than law enforcement. Social marketing yielded the lowest prevalence of self-reported attitude change. Our results show a potential moderate impact, measured as self-reported attitude change, resulting from the three intervention approaches under study. Future studies should address the intensity of exposure as well as the translation of attitude change into safer behaviors. Information generated by this study could be useful for local authorities in the intervention areas to inform their activities. Copyright © 2013 Elsevier Ltd. All rights reserved.

  13. Socioeconomic Position and Low Birth Weight among Mothers Exposed to Traffic-Related Air Pollution

    Science.gov (United States)

    Habermann, Mateus; Gouveia, Nelson

    2014-01-01

    Background Atmospheric pollution is a major public health concern. It can affect placental function and restricts fetal growth. However, scientific knowledge remains too limited to make inferences regarding causal associations between maternal exposure to air pollution and adverse effects on pregnancy. This study evaluated the association between low birth weight (LBW) and maternal exposure during pregnancy to traffic related air pollutants (TRAP) in São Paulo, Brazil. Methods and findings Analysis included 5,772 cases of term-LBW (<2,500 g) and 5,814 controls matched by sex and month of birth selected from the birth registration system. Mothers’ addresses were geocoded to estimate exposure according to 3 indicators: distance from home to heavy traffic roads, distance-weighted traffic density (DWTD) and levels of particulate matter ≤10 µg/m3 estimated through land use regression (LUR-PM10). Final models were evaluated using multiple logistic regression adjusting for birth, maternal and pregnancy characteristics. We found decreased odds in the risk of LBW associated with DWTD and LUR-PM10 in the highest quartiles of exposure with a significant linear trend of decrease in risk. The analysis with distance from heavy traffic roads was less consistent. It was also observed that mothers with higher education and neighborhood-level income were potentially more exposed to TRAP. Conclusions This study found an unexpected decreased risk of LBW associated with traffic related air pollution. Mothers with advantaged socioeconomic position (SEP) although residing in areas of higher vehicular traffic might not in fact be more expose to air pollution. It can also be that the protection against LBW arising from a better SEP is stronger than the effect of exposure to air pollution, and this exposure may not be sufficient to increase the risk of LBW for these mothers. PMID:25426640

  14. Situations of potential exposure in self-shielding electron accelerators

    International Nuclear Information System (INIS)

    Rios, D.A.S.; Rios, P.B.; Sordi, G.M.A.A.; Carneiro, J.C.G.G.

    2017-01-01

    The study discusses situations in the industrial environment that may lead to potential exposure of Occupationally Exposed Individuals and Public Individuals in self-shielding electron accelerators. Although these exposure situations are unlikely, simulation exercises can lead to improvements in the operating procedure as well as suggest changes in production line design in order to increase radiation protection at work. These studies can also be used in training and demonstrate a solid application of the ALARA principle in the daily activities of radiative installations

  15. The fate of chromosomal aberrations in 137Cs-exposed individuals in the Goiania radiation accident

    International Nuclear Information System (INIS)

    Ramalho, A.T.; Nascimento, A.C.

    1991-01-01

    Following the Goiania radiation accident, lymphocytes from 110 exposed or potentially exposed individuals were analyzed for the frequencies of chromosomal aberrations (dicentrics and centric rings) to estimate absorbed radiation dose. Dose estimates for 21 subjects exceeded 1.0 Gy, and for eight subjects they exceeded 4.0 Gy. Four of the subjects died. After the emergency period, a cytogenetic follow-up of 10 of the highest exposed patients was started. The results suggest that the average disappearance half-time of lymphocytes containing dicentric and centric rings was 130 d, which is shorter than the usually accepted value of 3 y reported in the literature

  16. Direct assessment of cumulative aryl hydrocarbon receptor agonist activity in sera from experimentally exposed mice and environmentally exposed humans

    DEFF Research Database (Denmark)

    Schlezinger, Jennifer J; Bernard, Pamela L; Haas, Amelia

    2010-01-01

    (PCB)-exposed Faroe Islanders using an AhR-driven reporter cell line. To validate relationships between serum AhR agonist levels and biological outcomes, AhR agonist activity in mouse sera correlated with toxic end points. AhR agonist activity in unmanipulated ("neat") human sera was compared......, was associated with the frequency of recent pilot whale dinners, but did not correlate with levels of PCBs quantified by GC/MS. Surprisingly, significant "baseline" AhR activity was found in commercial human sera. CONCLUSIONS: An AhR reporter assay revealed cumulative levels of AhR activation potential in neat...

  17. Individual doses' register of occupationally exposed persons in the Republic of Moldova

    International Nuclear Information System (INIS)

    Hustuc, A.; Chiruta, Iu.

    2009-01-01

    The storage and processing of the data acquired through different monitoring techniques are of vital importance for controlling the individual doses of the occupationally exposed workers facilitating the determination of exposure pathway and furthering the policy of radiological protection. The use of the data bases for the evidence of the individual doses of the occupationally exposed workers to the ionizing radiation is useful in studies of risks and potential exposure, and in future epidemiological studies. (authors)

  18. Oxidative damage of DNA in subjects occupationally exposed to lead.

    Science.gov (United States)

    Pawlas, Natalia; Olewińska, Elżbieta; Markiewicz-Górka, Iwona; Kozłowska, Agnieszka; Januszewska, Lidia; Lundh, Thomas; Januszewska, Ewa; Pawlas, Krystyna

    2017-09-01

    Exposure to lead (Pb) in environmental and occupational settings continues to be a serious public health problem and may pose an elevated risk of genetic damage. The aim of this study was to assess the level of oxidative stress and DNA damage in subjects occupationally exposed to lead. We studied a population of 78 male workers exposed to lead in a lead and zinc smelter and battery recycling plant and 38 men from a control group. Blood lead levels were detected by graphite furnace atomic absorption spectrophotometry and plasma lead levels by inductively coupled plasma-mass spectrometry. The following assays were performed to assess the DNA damage and oxidative stress: comet assay, determination of 8-hydroxy-2'-deoxyguanosine (8-OHdG), lipid peroxidation and total antioxidant status (TAS). The mean concentration of lead in the blood of the exposed group was 392 ± 103 μg/L and was significantly higher than in the control group (30.3 ± 29.4 μg/L, p lead exposure [lead in blood, lead in plasma, zinc protoporphyrin (ZPP)] and urine concentration of 8-OHdG. The level of oxidative damage of DNA was positively correlated with the level of lipid peroxidation (TBARS) and negatively with total anti-oxidative status (TAS). Our study suggests that occupational exposure causes an increase in oxidative damage to DNA, even in subjects with relatively short length of service (average length of about 10 years). 8-OHdG concentration in the urine proved to be a sensitive and non-invasive marker of lead induced genotoxic damage.

  19. Exposing the cancer genome atlas as a SPARQL endpoint

    Science.gov (United States)

    Deus, Helena F.; Veiga, Diogo F.; Freire, Pablo R.; Weinstein, John N.; Mills, Gordon B.; Almeida, Jonas S.

    2011-01-01

    The Cancer Genome Atlas (TCGA) is a multidisciplinary, multi-institutional effort to characterize several types of cancer. Datasets from biomedical domains such as TCGA present a particularly challenging task for those interested in dynamically aggregating its results because the data sources are typically both heterogeneous and distributed. The Linked Data best practices offer a solution to integrate and discover data with those characteristics, namely through exposure of data as Web services supporting SPARQL, the Resource Description Framework query language. Most SPARQL endpoints, however, cannot easily be queried by data experts. Furthermore, exposing experimental data as SPARQL endpoints remains a challenging task because, in most cases, data must first be converted to Resource Description Framework triples. In line with those requirements, we have developed an infrastructure to expose clinical, demographic and molecular data elements generated by TCGA as a SPARQL endpoint by assigning elements to entities of the Simple Sloppy Semantic Database (S3DB) management model. All components of the infrastructure are available as independent Representational State Transfer (REST) Web services to encourage reusability, and a simple interface was developed to automatically assemble SPARQL queries by navigating a representation of the TCGA domain. A key feature of the proposed solution that greatly facilitates assembly of SPARQL queries is the distinction between the TCGA domain descriptors and data elements. Furthermore, the use of the S3DB management model as a mediator enables queries to both public and protected data without the need for prior submission to a single data source. PMID:20851208

  20. Exposing the QCD Splitting Function with CMS Open Data.

    Science.gov (United States)

    Larkoski, Andrew; Marzani, Simone; Thaler, Jesse; Tripathee, Aashish; Xue, Wei

    2017-09-29

    The splitting function is a universal property of quantum chromodynamics (QCD) which describes how energy is shared between partons. Despite its ubiquitous appearance in many QCD calculations, the splitting function cannot be measured directly, since it always appears multiplied by a collinear singularity factor. Recently, however, a new jet substructure observable was introduced which asymptotes to the splitting function for sufficiently high jet energies. This provides a way to expose the splitting function through jet substructure measurements at the Large Hadron Collider. In this Letter, we use public data released by the CMS experiment to study the two-prong substructure of jets and test the 1→2 splitting function of QCD. To our knowledge, this is the first ever physics analysis based on the CMS Open Data.

  1. Patients exposed to therapeutic irradiation for benign conditions in childhood

    International Nuclear Information System (INIS)

    Carroll, R.G.

    1976-01-01

    In the United States there are over 1 million individuals who have been irradiated for benign conditions in the head and neck. Many recent reports document conclusively that individuals who have had head and neck radiation for benign conditions have markedly increased risk of thyroid, salivary, and perhaps breast cancer as compared to the general population. Although the relative risk as compared to the general population is high, the risk that any one individual who has had head or neck irradiation will develop a subsequent malignancy is relatively low. Identification of these patients through some type of screening procedure may be beneficial in terms of prevention of subsequent mortality and morbidity from cancer, especially thyroid and salivary cancer. The American Medical Association and the American Hospital Association issued a joint statement of October 17, 1975, urging hospitals and physicians to work together in their communities to develop guidelines and procedures for screening of exposed individuals and for public education

  2. Stability of people exposed to water flows

    Directory of Open Access Journals (Sweden)

    E. Martínez-Gomariz

    2016-01-01

    Full Text Available Our cities are formed by several elements which are exposed to floods of a magnitude according to the importance of the rainfall event and the design of the urban drainage system. The most important components in the cities are the pedestrians who develop various activities during rain events. Focusing on pedestrians, the research on their stability when they are exposed to water flows provides the necessary knowledge to understand and manage the associated hazard for them. In this research, several experiments with humans were carried out in order to determine the stability limits to pedestrians crossing through a water flow in a real scale platform. The results obtained and by comparing those with human stability criteria proposed by other authors and guidelines provide a more restrictive criterion.

  3. Children exposed to war/terrorism.

    Science.gov (United States)

    Shaw, Jon A

    2003-12-01

    This paper reviews the prevalence of psychological morbidities in children who have been exposed to war-related traumas or terrorism as well as the diversity of war-related casualties and their associated psychological responses. The psychological responses to war-related stressors are categorized as (1) little or no reaction, (2) acute emotional and behavioral effects, and (3) long-term effects. Specific categories of war-related casualties discussed include refugee status, traumatic bereavement, effects of parental absence, and child soldiers. Psychological responses associated with terrorism and bioterrorism are presented. Lastly, mediators of the psychological response to war-related stressors are discussed, to include exposure effects, gender effects, parental, family and social factors, and child-specific factors. Children exposed to war-related stressors experience a spectrum of psychological morbidities including posttraumatic stress symptomatology, mood disorders, externalizing and disruptive behaviors, and somatic symptoms determined by exposure dose effect. Specific questions for future research are identified.

  4. Color discrimination impairment in workers exposed to mercury vapor.

    Science.gov (United States)

    Urban, Pavel; Gobba, Fabriziomaria; Nerudová, Jana; Lukás, Edgar; Cábelková, Zdena; Cikrt, Miroslav

    2003-08-01

    To study color discrimination impairment in workers exposed to elemental mercury (Hg) vapor. Twenty-four male workers from a chloralkali plant exposed to Hg vapor, aged 42+/-9.8 years, duration of exposure 14.7+/-9.7 years, were examined. The 8h TWA air-borne Hg concentration in workplace was 59 microg/m(3); mean Hg urinary excretion (HgU) was 20.5+/-19.3 microg/g creatinine; mean Hg urinary excretion after the administration of a chelating agent, sodium 2,3-dimercapto-1-propane-sulfonate (DMPS), was 751.9+/-648 microg/48h. Twenty-four age- and gender-matched control subjects were compared. Visual acuity, alcohol intake, smoking habits, and history of diseases or drugs potentially influencing color vision were registered. The Lanthony 15-Hue desaturated test (L-D15-d) was used to assess color vision. The results were expressed quantitatively as Bowman's Color Confusion Index (CCI), and qualitatively according to Verriest's classification of acquired dyschromatopsias. The CCI was significantly higher in the exposed group than in the control (mean CCI 1.15 versus 1.04; P=0.04). The proportion of subjects with errorless performance on the Lanthony test was significantly lower in the Hg exposed group compared to referents (52% versus 73%; P=0.035). The exposed group showed higher frequency of type III dyschromatopsias (blue-yellow confusion axis) in comparison with the control group (12.5% versus 8.3%), however, the difference did not reach statistical significance. Multiple regression did not show any significant relationship between the CCI, and age, alcohol consumption, or measures of exposure. In agreement with previous studies by Cavalleri et al. [Toxicol. Lett. 77 (1995) 351; Environ. Res. Sec. A 77 (1998) 173], the results of this study support the hypothesis that exposure to mercury vapor can induce sub-clinical color vision impairment. This effect was observed at an exposure level below the current biological limit for occupational exposure to mercury. This

  5. Academic Publications

    OpenAIRE

    Francisco H C Felix

    2017-01-01

    Alternative modes of academic publication. What it is: Page for the dissemination of academic papers in alternative formats. Aimed at the diffusion of the idea of open publication, or open access publication, a branch of open science, a multidisciplinary movement that seeks to modify the paradigm of knowledge production that centralizes it and prevents its spreading. Historically, Western tradition has become firmly rooted in the free dissemination of knowledge among peers. However, the c...

  6. Public transport

    OpenAIRE

    Lethbridge, Jane

    2008-01-01

    Public transport plays an essential role in enabling people from low income and other disadvantaged groups to access employment and services. It also contributes to the development of social networks and social capital, by helping people to visit friends and relatives and take part in community and other social activities. Public policy makers have begun to recognise that adequate public transport provision can play an important role in reducing social exclusion. [Taken from introductory para...

  7. Bisphenol S (BPS) Alters Maternal Behavior and Brain in Mice Exposed During Pregnancy/Lactation and Their Daughters.

    Science.gov (United States)

    Catanese, Mary C; Vandenberg, Laura N

    2017-03-01

    Estrogenic endocrine disrupting chemicals have been shown to disrupt maternal behavior in rodents. We investigated the effects of an emerging xenoestrogen, bisphenol S (BPS), on maternal behavior and brain in CD-1 mice exposed during pregnancy and lactation (F0 generation) and in female offspring exposed during gestation and perinatal development (F1 generation). We observed different effects in F0 and F1 dams for a number of components of maternal behavior, including time on the nest, time spent on nest building, latency to retrieve pups, and latency to retrieve the entire litter. We also characterized expression of estrogen receptor α in the medial preoptic area (MPOA) and quantified tyrosine hydroxylase immunoreactive cells in the ventral tegmental area, 2 brain regions critical for maternal care. BPS-treated females in the F0 generation had a statistically significant increase in estrogen receptor α expression in the caudal subregion of the central MPOA in a dose-dependent manner. In contrast, there were no statistically significant effects of BPS on the MPOA in F1 dams or the ventral tegmental area in either generation. This work demonstrates that BPS affects maternal behavior and brain with outcomes depending on generation, dose, and postpartum period. Many studies examining effects of endocrine disrupting chemicals view the mother as a means by which offspring can be exposed during critical periods of development. Here, we demonstrate that pregnancy and lactation are vulnerable periods for the mother. We also show that developmental BPS exposure alters maternal behavior later in adulthood. Both findings have potential public health implications. Copyright © 2017 by the Endocrine Society.

  8. Public Transparency

    OpenAIRE

    UNCTAD; World Bank

    2018-01-01

    This note provides guidance on the type of information about agricultural investments that investors and governments can make publicly available. Transparency about certain aspects of investments can improve relations between investors and communities, enable external stakeholders to hold investors to commitments, and improve investors’ public image. Although some information should be kep...

  9. Public relations

    International Nuclear Information System (INIS)

    1998-01-01

    Public relations activities continued in a well-proved form of organizing plant visits and Information Centre off - site activities. Bohunice NPPs were visited by the number of 7294 visitors in 1997. A brief account of activities in public relations carried out by the Nuclear power plants Jaslovske Bohunice in 1997 is presented

  10. DNA damage and cytotoxicity in pathology laboratory technicians exposed to organic solvents

    Directory of Open Access Journals (Sweden)

    TATIANE DE AQUINO

    2016-03-01

    Full Text Available The aim of this study was to evaluate potential DNA damage and cytotoxicity in pathology laboratory technicians exposed to organic solvents, mainly xylene. Peripheral blood and buccal cells samples were collected from 18 technicians occupationally exposed to organic solvents and 11 non-exposed individuals. The technicians were sampled at two moments: Monday and Friday. DNA damage and cytotoxicity were evaluated using the Comet Assay and the Buccal Micronucleus Cytome assay. Fifteen subjects (83.5% of the exposed group to solvents complained about some symptom probably related to contact with vapours of organic solvents. DNA damage in the exposed group to solvents was nearly 2-fold higher on Friday than on Monday, and in both moments the individuals of this group showed higher levels of DNA damage in relation to controls. No statistical difference was detected in buccal cell micronucleus frequency between the laboratory technicians and the control group. However, in the analysis performed on Friday, technicians presented higher frequency (about 3-fold of karyolytic and apoptotic-like cells (karyorrhectic and pyknotic in relation to control group. Considering the damage frequency and the working time, a positive correlation was found in the exposed group to solvents (r=0.468; p=0.05. The results suggest that pathology laboratory workers inappropriately exposed to organic solvents have increased levels of DNA damage.

  11. EXPOSE-R2: The Astrobiological ESA Mission on Board of the International Space Station

    Directory of Open Access Journals (Sweden)

    Elke Rabbow

    2017-08-01

    Full Text Available On July 23, 2014, the Progress cargo spacecraft 56P was launched from Baikonur to the International Space Station (ISS, carrying EXPOSE-R2, the third ESA (European Space Agency EXPOSE facility, the second EXPOSE on the outside platform of the Russian Zvezda module, with four international astrobiological experiments into space. More than 600 biological samples of archaea, bacteria (as biofilms and in planktonic form, lichens, fungi, plant seeds, triops eggs, mosses and 150 samples of organic compounds were exposed to the harsh space environment and to parameters similar to those on the Mars surface. Radiation dosimeters distributed over the whole facility complemented the scientific payload. Three extravehicular activities later the chemical samples were returned to Earth on March 2, 2016, with Soyuz 44S, having spent 588 days in space. The biological samples arrived back later, on June 18, 2016, with 45S, after a total duration in space of 531 days. The exposure of the samples to Low Earth Orbit vacuum lasted for 531 days and was divided in two parts: protected against solar irradiation during the first 62 days, followed by exposure to solar radiation during the subsequent 469 days. In parallel to the space mission, a Mission Ground Reference (MGR experiment with a flight identical Hardware and a complete flight identical set of samples was performed at the premises of DLR (German Aerospace Center in Cologne by MUSC (Microgravity User Support Center, according to the mission data either downloaded from the ISS (temperature data, facility status, inner pressure status or provided by RedShift Design and Engineering BVBA, Belgium (calculated ultra violet radiation fluence data. In this paper, the EXPOSE-R2 facility, the experimental samples, mission parameters, environmental parameters, and the overall mission and MGR sequences are described, building the background for the research papers of the individual experiments, their analysis and results.

  12. Towards harmonized qualifications for radiation exposed personnel

    International Nuclear Information System (INIS)

    Briso, Hugo A.

    2008-01-01

    The accelerated process of globalization affecting mankind doesn't exclude safety matters. Indeed, some trans national corporations are increasingly offering specialized engineering services such as industrial radiography or well lodging. As well, a growing scientific exchange involves the mobility of nuclear researchers in different areas, for instance radiochemistry, nuclear medicine and radiotherapy. Such a breakdown in the technological frontiers must necessarily be reflected by the regulatory solutions. Particularly, diverse levels of theoretical-practical training for radiation exposed personnel coexist in the Latin-American Region, being an especially sensitive problem for radiation protection matters. The spectrum goes from post-graduate courses required for radiation protection officers in some countries, while in others only basic recommendations are required for the operating personnel. Another scheme consists of medium level course for the operating personnel, while radiation protection officers don't have special requirements. Many educational private institutions teach non standardized courses which only give broad concepts of radiation protection. On the other hand, usually nothing is said about the operational training, or else its certification is entrusted to the employer itself. In some countries multiple Regulatory Authorities apply dissimilar criteria to assess safety matters, including the evaluation of workers applications. The necessary regional integration makes indispensable to establish common standards for granting authorizations. Having similar or homogeneous requirements for the universe of radiation exposed personnel, i.e. source operators, radiation protection officers, qualified experts and technical support people would be easier for the Regulatory Authorities to have common methodologies of evaluation for the applicants. An IAEA supported technical cooperation project related to this paper seeks to establish standardized

  13. Lymphocytic subsets in occupationally exposed persons

    International Nuclear Information System (INIS)

    Tuschl, H.; Kovac, R.; Wottawa, A.

    1989-04-01

    The percentage of CD2, CD4, CD8 and NK cells of peripheral blood was investigated in persons occupationally exposed to very low doses of ionizing radiation. Investigations were carried out by monoclonal antibodies and flow-cytometry. While significant effects of age and smoking habits on the relative number of CD8 cells and CD4/CD8 ratios could be established, no influence of the very low radiation exposure on the profile of lymphocytic cells in blood was found, except a very slight effect on the relative number of total T cells (= CD2 cells). 7tabs., 2figs., 16refs. (Author)

  14. Renographic curve of persons exposed to mercury

    International Nuclear Information System (INIS)

    Kolenic, J.; Jurgova, T.; Zimacek, J.; Petrovicova, J.; Bilicky, J.

    1995-01-01

    In the group of 72 workers which were exposed to fumes of metallic mercury we evaluated possible nephrotoxic effect of Hg 0 . We also used nuclear renography for evaluation of kidney. Nephrotoxic effect of Hg 0 was proved by increased proteinuria and relatively frequent findings of pathological renogram. In the group with pathological renogram, elimination of Hg 0 in urine (1822.8 nmol.dm -3 ) was increased. In the group with normal finding the value was 883.7 nmol.dm -3 . These findings pointed at toxic effect of Hg 0 on kidney and suitability of radionuclide examination for disclosing of subclinical pathological changes. (authors)

  15. Spoiled Onions: Exposing Malicious Tor Exit Relays

    OpenAIRE

    Winter, Philipp; Lindskog, Stefan

    2014-01-01

    Several hundred Tor exit relays together push more than 1 GiB/s of network traffic. However, it is easy for exit relays to snoop and tamper with anonymised network traffic and as all relays are run by independent volunteers, not all of them are innocuous. In this paper, we seek to expose malicious exit relays and document their actions. First, we monitored the Tor network after developing a fast and modular exit relay scanner. We implemented several scanning modules for detecting common attac...

  16. Uniform Protection for Multi-exposed Targets

    DEFF Research Database (Denmark)

    Vigo, Roberto; Nielson, Flemming; Nielson, Hanne Riis

    2014-01-01

    the Quality Calculus that computes the combinations of data required to reach a program point and relates them to a notion of cost. In this way, we can compare the security deployed on different paths that expose the same resource. The analysis is formalised in terms of flow logic, and is implemented......Ensuring that information is protected proportionately to its value is a major challenge in the development of robust distributed systems, where code complexity and technological constraints might allow reaching a key functionality along various paths. We propose a protection analysis over...

  17. Backfilling of trenches exposed to waves

    DEFF Research Database (Denmark)

    Hjelmager Jensen, Jacob; Fredsøe, Jørgen

    1997-01-01

    This paper treats the numerical prediction of initial and long-term morphology of small pipeline trenches. For this purpose a refined flow and sediment transport description is applied such that the entire mathematical problem is formulated and solved on a curvilinear grid using a k - ε turbulence......-closure. The backfilling process of trenches exposed to either waves or a steady current is of importance in relation to the implementation of pipelines in the marine environment. With respect to the sedimentation of trenches, the non-dimensional Trench-Keulegan-Carpenter number, KC = a/L, where a is the excursion length...

  18. Analyses of Concrete Structures Exposed to Fire

    DEFF Research Database (Denmark)

    Hertz, Kristian

    The text book contains the data and methods necessary for fire safety design of concrete constructions. The methods relate to standard fire as well as to any time of any other fire course.Material data are presented for concretes exposed to fire, and calculation methods are given for the ultimate...... bending capacity of beams and slabs, the ultimate shear capacity of beams, for the instability of columns and walls and for the deflection of prestressed and non-prestressed beams, slabs, walls and columns.All methods have been derived and compared to tests by Kristian Hertz....

  19. Pregnant women in Timis County, Romania are exposed primarily to low-level (water consumption.

    Science.gov (United States)

    Neamtiu, Iulia; Bloom, Michael S; Gati, Gabriel; Goessler, Walter; Surdu, Simona; Pop, Cristian; Braeuer, Simone; Fitzgerald, Edward F; Baciu, Calin; Lupsa, Ioana Rodica; Anastasiu, Doru; Gurzau, Eugen

    2015-06-01

    Excessive arsenic content in drinking water poses health risks to millions of people worldwide. Inorganic arsenic (iAs) in groundwater exceeding the 10μg/l maximum contaminant level (MCL) set by the World Health Organization (WHO) is characteristic for intermediate-depth aquifers over large areas of the Pannonian Basin in Central Europe. In western Romania, near the border with Hungary, Arad, Bihor, and Timis counties use drinking water coming partially or entirely from iAs contaminated aquifers. In nearby Arad and Bihor counties, more than 45,000 people are exposed to iAs over 10μg/l via public drinking water sources. However, comparable data are unavailable for Timis County. To begin to address this data gap, we determined iAs in 124 public and private Timis County drinking water sources, including wells and taps, used by pregnant women participating in a case-control study of spontaneous loss. Levels in water sources were low overall (median=3.0; range=water sources compared to 10 women using uncontaminated sources for urine total iAs (6.6 vs. 5.0μg/l, P=0.24) and DMA (5.5 vs. 4.2μg/l, P=0.31). The results suggested that the origin of urine total iAs (r=0.35, P=0.13) and DMA (r=0.31, P=0.18) must have been not only iAs in drinking-water but also some other source. Exposure of pregnant women to arsenic via drinking water in Timis County appears to be lower than for surrounding counties; however, it deserves a more definitive investigation as to its origin and the regional distribution of its risk potential. Copyright © 2015 Elsevier GmbH. All rights reserved.

  20. Effects of volcanic deposit disaggregation on exposed water composition

    Science.gov (United States)

    Back, W. E.; Genareau, K. D.

    2016-12-01

    Explosive volcanic eruptions produce a variety of hazards. Pyroclastic material can be introduced to water through ash fallout, pyroclastic flows entering water bodies, and/or lahars. Remobilization of tephras can occur soon after eruption or centuries later, introducing additional pyroclastic material into the environment. Introduction of pyroclastic material may alter the dissolved element concentration and pH of exposed waters, potentially impacting drinking water supplies, agriculture, and ecology. This study focuses on the long-term impacts of volcanic deposits on water composition due to the mechanical breakup of volcanic deposits over time. Preliminary work has shown that mechanical milling of volcanic deposits will cause significant increases in dissolved element concentrations, conductivity, and pH of aqueous solutions. Pyroclastic material from seven eruptions sites was collected, mechanically milled to produce grain sizes Soufriere Hills, Ruapehu), mafic (Lathrop Wells) and ultramafic (mantle xenoliths) volcanic deposits. Lathrop Wells has an average bulk concentration of 49.15 wt.% SiO2, 6.11 wt. % MgO, and 8.39 wt. % CaO and produces leachate concentrations of 85.69 mg/kg for Ca and 37.22 mg/kg for Mg. Taupo and Valles Caldera samples have a bulk concentration of 72.9 wt.% SiO2, 0.59 wt. % MgO, and 1.48 wt. % CaO, and produces leachate concentrations of 4.08 mg/kg for Ca and 1.56 mg/kg for Mg. Similar testing will be conducted on the intermediate and ultramafic samples to test the hypothesis that bulk magma composition and mineralogy will directly relate to the increased dissolved element concentration of exposed waters. The measured effects on aqueous solutions will aid in evaluation of impacts to marine and freshwater systems exposed to volcanic deposits.

  1. Publications, 1978

    International Nuclear Information System (INIS)

    Hilborn, H.S.

    1979-03-01

    This is a compilation of documents that communicate the results of scientific and technical work done at Savannah River. The compilation includes those documents that have been published (research and development reports, journal articles, book chapters, etc.), documents that have been announced in Energy Research Abstracts, and papers that have been presented at technical meetings but have not yet been published or announced. The information was compiled by machine methods to produce bibliographic, subject, and author listings. This report updates the information included in DP-929, Rev. 2, Publications, 1951 through 1971 DP-929-1, Publications, 1972 through 1976, and DP-929-1, Supplement 1, Publications, 1977

  2. Occupational health care of radiation exposed workers

    International Nuclear Information System (INIS)

    Abdul Rahim Rahman Hamzah

    1995-01-01

    The medical problems encountered by the earlier pioneer workers in radiation at the turn of the century are well known. In the 1928, the ICRP (International Committee for Radiological Protection) was instituted and the ALARA principle of radiation protection was evolved. Occupational health care is about maintaining the health and safety of workers in their workplaces. This involves using medical, nursing and engineering practices to achieve its objectives. In certain occupations, including those where workers are exposed to ionising radiation, some of these principles are enshrined in the legislation and would require statutory compliance. Occupational health care of radiation workers seek to prevent ill health arising from exposure to radiation by consolidating the benefits of exposures control and dosimetry. This is via health surveillance for spillages, contamination and exposures to unsealed sources of radiation. It is unlikely that can plan and hope to cater for a Chernobyl type of disaster. However, for the multitude of workers in industry exposed to radiation, control models are available. These are from the more in industrialize countries with a nuclear based energy industry, and where radioactive gadgetry are used in places ranging from factories and farms to construction sites. These models involve statutory requirements on the standard of work practices, assessment of fitness to work and the monitoring of both the worker and the workplace. A similar framework of activity is present in Malaysia. This will be further enhanced with the development of her general health and safety at work legislation. (author)

  3. Protection of man: the exposed individual

    Energy Technology Data Exchange (ETDEWEB)

    Bohnstedt, A.; Knebel, J.U. [Programme Nuclear Safety Research, Karlsruhe Institute of Technology, Herrmann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen (Germany); Breustedt, B. [Institute for Radiation Research, Karlsruhe Institute of Technology, Herrmann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen (Germany)

    2010-07-01

    Present methods for quantifying radiation exposure rely on a standardized reference man (75 kg) with defined average anatomical and physiological data. But individual person actually exposed differs from this idealized standard man. Therefore the focus of investigations at the Institute for Radiation Research (Institut fuer Strahlenforschung, ISF) which was founded at Karlsruhe Institute of Technology (Karlsruher Institut fuer Technologie, KIT) in 2009 is based on the vision to place the exposed individual with its anatomical and physiological particularities, under consideration of age, gender, body height, body shape and environment, in the centre of an individual-related quantification of the external and internal radiation exposure. Research work at the ISF is aiming at quantifying radiation exposure by improved determination of doses essentially caused by external radiation fields and the intake of radionuclides into the body. The three main topics of the institute are - external dosimetry (e.g. using a (voxel) model of the hand to simulate skin dose distribution); - internal dosimetry (e.g. body size related efficiency calibration of in-vivo counting equipment); - numerical methods/modeling (e.g. development of a mathematical/voxel-hybrid model of the human body). (authors)

  4. Zirconium ignition in exposed fuel channel

    Energy Technology Data Exchange (ETDEWEB)

    Elias, E., E-mail: merezra@technion.ac.il; Hasan, D.; Nekhamkin, Y.

    2015-05-15

    Highlights: • We demonstrate the idea of runaway zirconium–steam reactions in severe accidents in today's LWRs. • We predict the thermal-hydraulics conditions relevant to cladding oxidation in an exposed fuel channel of a partially uncovered core. • The Semenov theory of metal combustion is extended to define a criterion for runaway oxidation reaction in fuel cladding. - Abstract: A theoretical model based on simultaneous solution of the heat and mass transfer equations is developed for predicting the rate of thermo-chemical reaction between zirconium cladding and a hot steam environment. Ignition conditions relevant to cladding oxidation in an exposed fuel channel of a partially uncovered core are predicted based on the theory of metal combustion. A range of decay power, convective heat transfer coefficients, and initial temperatures leading to uncontrolled runaway cladding oxidation is identified. The model could be readily integrated as part of a fuel channel analysis code for predicting possible outcomes of different accident mitigation procedures in light water nuclear reactors under LOCA conditions.

  5. Spatial variability of macrobenthic zonation on exposed sandy beaches

    Science.gov (United States)

    Veiga, Puri; Rubal, Marcos; Cacabelos, Eva; Maldonado, Cristina; Sousa-Pinto, Isabel

    2014-07-01

    We analysed the consistence of vertical patterns of distribution (i.e. zonation) for macrofauna at different spatial scales on four intermediate exposed beaches in the North of Portugal. We tested the hypothesis that biological zonation on exposed sandy beaches would vary at the studied spatial scales. For this aim, abundance, diversity and structure of macrobenthic assemblages were examined at the scales of transect and beach. Moreover, the main environmental factors that could potentially drive zonation patterns were investigated. Univariate and multivariate analyses revealed that the number of biological zones ranged from two to three depending on the beach and from indistinct zonation to three zones at the scale of transect. Therefore, results support our working hypothesis because zonation patterns were not consistent at the studied spatial scales. The median particle size, sorting coefficient and water content were significantly correlated with zonation patterns of macrobenthic assemblages. However, a high degree of correlation was not reached when the total structure of the assemblage was considered.

  6. Thyroid neoplasia in Marshall Islanders exposed to nuclear fallout

    International Nuclear Information System (INIS)

    Hamilton, T.E.; van Belle, G.; LoGerfo, J.P.

    1987-01-01

    We studied the risk of thyroid neoplasia in Marshall Islanders exposed to radioiodines in nuclear fallout from the 1954 BRAVO thermonuclear test. We screened 7266 Marshall Islanders for thyroid nodules; the islanders were from 14 atolls, including several southern atolls, which were the source of the best available unexposed comparison group. Using a retrospective cohort design, we determined the prevalence of thyroid nodularity in a subgroup of 2273 persons who were alive in 1954 and who therefore were potentially exposed to fallout from the BRAVO test. For those 12 atolls previously thought to be unexposed to fallout, the prevalence of thyroid nodules ranged from 0.9% to 10.6%. Using the distance of each atoll from the test site as a proxy for the radiation dose to the thyroid gland, a weighted linear regression showed an inverse linear relationship between distance and the age-adjusted prevalence of thyroid nodules. Distance was the strongest single predictor in logistic regression analysis. A new absolute risk estimate was calculated to be 1100 excess cases/Gy/y/1 X 10(6) persons (11.0 excess cases/rad/y/1 million persons), 33% higher than previous estimates. We conclude that an excess of thyroid nodules was not limited only to the two northern atolls but extended throughout the northern atolls; this suggests a linear dose-response relationship

  7. Geomatics and public health.

    Science.gov (United States)

    Jaishankar, R; Jhonson, C P

    2006-01-01

    Geomatics technology has tremendous potential to address public health issues particularly under the present circumstances of global climate change and climate or technology induced human migration, which result in an increase in the geographical extent and re-emergence of vector-borne diseases. The authors present an overview of the science of geomatics, describe the potential impacts of climate change on vector-borne diseases and review the applications of remote sensing for disease vector surveillance.

  8. Psychosocial consequences of the Chernobyl disaster (A survey of Chernobyl accidental exposed and a non-exposed population sample)

    International Nuclear Information System (INIS)

    Havenaar, J.M.; Savelkoul, T.J.F.; Bout, J. van-den; Bootsma, P.A.

    1996-01-01

    The importance of psychological factors in the aftermath of industrial disasters is being recognized increasingly. Two field studies (total N=3084) were conducted in two regions of the former Soviet Union, to investigate the long-term psychosocial consequences of the Chernobyl nuclear power plant disaster in 1986. A sub sample of the respondents (N=449) was studied using a standardized physical and psychiatric examination. The first study took place in the Gomel region (Belarus) in the direct vicinity of the damaged nuclear plant. A control study was conducted in the Tver region (the Russian Federation), about 250 km north-west of Moscow. The results of the study indicate significantly higher levels of psychological distress, poorer subjective health and higher medical consumption in the exposed population. These findings were most prominent in risk groups such as evacuated people and mothers with children. No significant differences in overall levels of psychiatric or physical morbidity were found. Radiation related diseases could not account for the poor health perception in the investigated sample. These results indicate that psychological factors following the Chernobyl disaster had a marked effect upon psychological well being, on perceived health and on subsequent illness behavior. Fears about future health play a key role in determining this response. The provision of adequate information to the public as well as to the public health services may be important to counteract these fears

  9. Public Airports

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This data set is a vector point digital data structure that contains the locations of General Public Use Airports in the State of New Mexico. It only contains those...

  10. Public Sociology

    DEFF Research Database (Denmark)

    by the media? Does the choice of public sociology mean the relinquishment of scientific integrity and critical conviction? These questions will also be addressed in this book - together with a host of others related to the topic of public sociology.   The chapters included in this book are all manuscripts......What is the role of sociology in society? How can - and should - sociology contribute with insights relevant and useful to the outside world? Is sociology attuned to accommodate the demands of the wider public and of surrounding society? Who benefits from the knowledge produced and provided...... by sociology? What are the social implications and cultural effects of the knowledge sociology provides and creates? All of these questions, and many others, concern and centre on sociology's relationship to the surrounding society, in short to the ‘public'. All of these questions - and many others...

  11. The affect of the space environment on the survival of Halorubrum chaoviator and Synechococcus (Nägeli): data from the Space Experiment OSMO on EXPOSE-R

    Science.gov (United States)

    Mancinelli, R. L.

    2015-01-01

    We have shown using ESA's Biopan facility flown in Earth orbit that when exposed to the space environment for 2 weeks the survival rate of Synechococcus (Nägeli), a halophilic cyanobacterium isolated from the evaporitic gypsum-halite crusts that form along the marine intertidal, and Halorubrum chaoviator a member of the Halobacteriaceae isolated from an evaporitic NaCl crystal obtained from a salt evaporation pond, were higher than all other test organisms except Bacillus spores. These results led to the EXPOSE-R mission to extend and refine these experiments as part of the experimental package for the external platform space exposure facility on the ISS. The experiment was flown in February 2009 and the organisms were exposed to low-Earth orbit for nearly 2 years. Samples were either exposed to solar ultraviolet (UV)-radiation (λ > 110 nm or λ > 200 nm, cosmic radiation (dosage range 225-320 mGy), or kept in darkness shielded from solar UV-radiation. Half of each of the UV-radiation exposed samples and dark samples were exposed to space vacuum and half kept at 105 pascals in argon. Duplicate samples were kept in the laboratory to serve as unexposed controls. Ground simulation control experiments were also performed. After retrieval, organism viability was tested using Molecular Probes Live-Dead Bac-Lite stain and by their reproduction capability. Samples kept in the dark, but exposed to space vacuum had a 90 +/- 5% survival rate compared to the ground controls. Samples exposed to full UV-radiation for over a year were bleached and although results from Molecular Probes Live-Dead stain suggested ~10% survival, the data indicate that no survival was detected using cell growth and division using the most probable number method. Those samples exposed to attenuated UV-radiation exhibited limited survival. Results from of this study are relevant to understanding adaptation and evolution of life, the future of life beyond earth, the potential for interplanetary

  12. The Affect of the Space Environment on the Survival of Halorubrum Chaoviator and Synechococcus (Nageli): Data from the Space Experiment OSMO on EXPOSE-R

    Science.gov (United States)

    Mancinelli, R. L.

    2014-01-01

    We have shown using ESA's Biopan facility flown in Earth orbit that when exposed to the space environment for 2 weeks the survival rate of Synechococcus (Nageli), a halophilic cyanobacterium isolated from the evaporitic gypsum-halite crusts that form along the marine intertidal, and Halorubrum chaoviator a member of the Halobacteriaceae isolated from an evaporitic NaCl crystal obtained from a salt evaporation pond, were higher than all other test organisms except Bacillus spores. These results led to the EXPOSE-R mission to extend and refine these experiments as part of the experimental package for the external platform space exposure facility on the ISS. The experiment was flown in February 2009 and the organisms were exposed to low-Earth orbit for nearly 2 years. Samples were either exposed to solar ultraviolet (UV)-radiation (lambda is greater than 110 nm or lambda is greater than 200 nm, cosmic radiation (dosage range 225-320 mGy), or kept in darkness shielded from solar UV-radiation. Half of each of the UV-radiation exposed samples and dark samples were exposed to space vacuum and half kept at 105 pascals in argon. Duplicate samples were kept in the laboratory to serve as unexposed controls. Ground simulation control experiments were also performed. After retrieval, organism viability was tested using Molecular Probes Live-Dead Bac-Lite stain and by their reproduction capability. Samples kept in the dark, but exposed to space vacuum had a 90 +/- 5% survival rate compared to the ground controls. Samples exposed to full UV-radiation for over a year were bleached and although results from Molecular Probes Live-Dead stain suggested approximately 10% survival, the data indicate that no survival was detected using cell growth and division using the most probable number method. Those samples exposed to attenuated UV-radiation exhibited limited survival. Results from of this study are relevant to understanding adaptation and evolution of life, the future of life

  13. Public meetings

    CERN Multimedia

    Staff Association

    2017-01-01

    Do you have questions about the elections to the Staff Council, 2017 MERIT exercise, EVE and School, LD to IC exercise, CHIS, the Pension Fund… Come get informed and ask your questions at our public meetings. These public meetings are also an opportunity to get the more information on current issues. Benefit from this occasion to get the latest news and to discuss with the representatives of the statutory body that is the Staff Association!

  14. To be a worker (exposed?) or not to be a worker (exposed?) that is the question

    International Nuclear Information System (INIS)

    Ammerich, M.

    2008-01-01

    The notion of personnel is detailed in this article in order to know exactly what personnel is considered as exposed and what radiation doses are under this term. The regulatory texts are studied in different articles of the French law and show that different kind of exposed personnel are considered. The definitions are varying with the notion of risk, of radiation doses and the work itself. This article asks for a better and more precise definition that will help the actors of radiation protection. (N.C.)

  15. Public Participation in the Energy-Related Public Policy Making

    International Nuclear Information System (INIS)

    Bozicevic Vrhovcak, M.; Rodik, D.; Zmijarevic, Z.; Jaksic, D.

    2011-01-01

    This paper provides an overview of possibilities for public participation in proposing legal acts and other energy related documents in the Republic of Croatia and gives author assessment of the Croatian public participation level in the processes carried out. The ways how public has participated in the making of a few officially accepted documents have been analysed and potential benefits of inclusion of a wider circle of interested public have been stated. A comparison of the degree of public involvement in the decision making processes in Croatia and the European Union has been made, with specific emphasis on the adoption of the Third package of energy laws. Several national and EU funded projects aiming at enhancing the Croatian public participation in public decision making processes have been presented and their results given. Finally, possibilities for the improvement of the public participation in the Croatian energy policy making processes are proposed. (author)

  16. The Challenges of Projecting the Public Health Impacts of Marijuana Legalization in Canada; Comment on “Legalizing and Regulating Marijuana in Canada: Review of Potential Economic, Social, and Health Impacts”

    OpenAIRE

    Stephanie Lake; Thomas Kerr

    2017-01-01

    A recent editorial in this journal provides a summary of key economic, social, and public health considerations of the forthcoming legislation to legalize, regulate, and restrict access to marijuana in Canada. As our government plans to implement an evidence-based public health framework for marijuana legalization, we reflect and expand on recent discussions of the public health implications of marijuana legalization, and offer additional points of consideration. We select two commonly cited ...

  17. Brain damage among the prenatally exposed

    International Nuclear Information System (INIS)

    Otake, Masanori; Schull, W.J.; Yoshimaru, Hiroshi.

    1991-01-01

    Significant effects on the developing brain of exposure to ionizing radiation are seen among those individuals exposed in the 8th through the 25th week after fertilization. These effects, particularly in the most sensitive period, 8-15 weeks after fertilization, manifest themselves as an increased frequency of severe mental retardation (SMR), a diminution in IQ score and in school performance, and an increase in the occurrence of seizures. Of 30 SMR cases, 18 (60%) had small heads. About 10% of the individuals with small head sizes observed among the in utero clinical sample were mentally retarded. When all of the cases of mental retardation are included in the analysis, a linear dose-response model fits the data adequately and no evidence of a threshold emerges; however, if the two probable nonradiation-related cases of Down's syndrome are excluded from the 19 SMR cases exposed 8-15 weeks after fertilization, the evidence of a threshold is stronger. The 95% lower bound of the threshold based on the new dosimetry system appears to be in the range of 0.12-0.23 Gy. In the 16-25 week period, the 95% lower bound of the threshold is 0.21 Gy both with and without inclusion of two probable nonradiation-related retarded cases. In a regression analysis of IQ scores and school performance data, a greater linearity is suggested with the new dosimetry (DS86) than with the old (T65DR), but the mean IQ score and the mean school performance of those exposed in utero to doses under 0.10 Gy are similar, and not statistically different from the means in the control group. The risk ratios for unprovoked seizures, following exposure during the 8th through the 15th week after fertilization, are 4.4 (90% confidence interval: 0.5-40.9) after 0.10-0.49 Gy and 24.9 (4.1-191.6) after 0.50 Gy or more when the mentally retarded are included and 4.4 (0.5-40.9) and 14.5 (0.4-199.6), respectively, when they are excluded. (author)

  18. Exposing the cancer genome atlas as a SPARQL endpoint.

    Science.gov (United States)

    Deus, Helena F; Veiga, Diogo F; Freire, Pablo R; Weinstein, John N; Mills, Gordon B; Almeida, Jonas S

    2010-12-01

    The Cancer Genome Atlas (TCGA) is a multidisciplinary, multi-institutional effort to characterize several types of cancer. Datasets from biomedical domains such as TCGA present a particularly challenging task for those interested in dynamically aggregating its results because the data sources are typically both heterogeneous and distributed. The Linked Data best practices offer a solution to integrate and discover data with those characteristics, namely through exposure of data as Web services supporting SPARQL, the Resource Description Framework query language. Most SPARQL endpoints, however, cannot easily be queried by data experts. Furthermore, exposing experimental data as SPARQL endpoints remains a challenging task because, in most cases, data must first be converted to Resource Description Framework triples. In line with those requirements, we have developed an infrastructure to expose clinical, demographic and molecular data elements generated by TCGA as a SPARQL endpoint by assigning elements to entities of the Simple Sloppy Semantic Database (S3DB) management model. All components of the infrastructure are available as independent Representational State Transfer (REST) Web services to encourage reusability, and a simple interface was developed to automatically assemble SPARQL queries by navigating a representation of the TCGA domain. A key feature of the proposed solution that greatly facilitates assembly of SPARQL queries is the distinction between the TCGA domain descriptors and data elements. Furthermore, the use of the S3DB management model as a mediator enables queries to both public and protected data without the need for prior submission to a single data source. Copyright © 2010 Elsevier Inc. All rights reserved.

  19. Mothers and infants exposed to intimate partner violence compensate.

    Science.gov (United States)

    Letourneau, Nicole; Morris, Catherine Young; Secco, Loretta; Stewart, Miriam; Hughes, Jean; Critchley, Kim

    2013-01-01

    Reasons for the developmental variability in children exposed to intimate partner violence (IPV) are unclear and under studied. This article presents exploratory findings on (a) the potential impact of IPV on mother-child relationships and child development and (b) the association between these maternal-child relationship impacts and child development. The fit of findings with compensatory, spillover, and compartmentalization hypotheses was explored. Participants were 49 mothers and 51 children younger than 3 years of age affected by IPV. Data were collected on maternal-child interactions, child development, social support, difficult life circumstances, family functioning, child temperament, and parental depression. The findings suggested developmental impacts on children in the sample, along with children's high sensitivity and responsiveness to their caregivers. Although some spillover effects were observed, the predominant observation was of mothers and infants compensating for exposure to IPV in their interactions.

  20. Health services research in the public healthcare system in Hong Kong: an analysis of over 1 million antihypertensive prescriptions between 2004-2007 as an example of the potential and pitfalls of using routinely collected electronic patient data.

    Science.gov (United States)

    Wong, Martin C S; Jiang, Johnny Y; Tang, Jin-ling; Lam, Augustine; Fung, Hong; Mercer, Stewart W

    2008-06-25

    Increasing use is being made of routinely collected electronic patient data in health services research. The aim of the present study was to evaluate the potential usefulness of a comprehensive database used routinely in the public healthcare system in Hong Kong, using antihypertensive drug prescriptions in primary care as an example. Data on antihypertensive drug prescriptions were retrieved from the electronic Clinical Management System (e-CMS) of all primary care clinics run by the Health Authority (HA) in the New Territory East (NTE) cluster of Hong Kong between January 2004 and June 2007. Information was also retrieved on patients' demographic and socioeconomic characteristics, visit type (new or follow-up), and relevant diseases (International Classification of Primary Care, ICPC codes). 1,096,282 visit episodes were accessed, representing 93,450 patients. Patients' demographic and socio-economic details were recorded in all cases. Prescription details for anti-hypertensive drugs were missing in only 18 patients (0.02%). However, ICPC-code was missing for 36,409 patients (39%). Significant independent predictors of whether disease codes were applied included patient age > or = 70 years (OR 2.18), female gender (OR 1.20), district of residence (range of ORs in more rural districts; 0.32-0.41), type of clinic (OR in Family Medicine Specialist Clinics; 1.45) and type of visit (OR follow-up visit; 2.39). In the 57,041 patients with an ICPC-code, uncomplicated hypertension (ICPC K86) was recorded in 45,859 patients (82.1%). The characteristics of these patients were very similar to those of the non-coded group, suggesting that most non-coded patients on antihypertensive drugs are likely to have uncomplicated hypertension. The e-CMS database of the HA in Hong Kong varies in quality in terms of recorded information. Potential future health services research using demographic and prescription information is highly feasible but for disease-specific research dependant

  1. Immune Response among Patients Exposed to Molds

    Directory of Open Access Journals (Sweden)

    Jordan N. Fink

    2009-12-01

    Full Text Available Macrocyclic trichothecenes, mycotoxins produced by Stachybotrys chartarum, have been implicated in adverse reactions in individuals exposed to mold-contaminated environments. Cellular and humoral immune responses and the presence of trichothecenes were evaluated in patients with mold-related health complaints. Patients underwent history, physical examination, skin prick/puncture tests with mold extracts, immunological evaluations and their sera were analyzed for trichothecenes. T-cell proliferation, macrocyclic trichothecenes, and mold specific IgG and IgA levels were not significantly different than controls; however 70% of the patients had positive skin tests to molds. Thus, IgE mediated or other non-immune mechanisms could be the cause of their symptoms.

  2. Reactivity of lithium exposed graphite surface

    International Nuclear Information System (INIS)

    Harilal, S.S.; Allain, J.P.; Hassanein, A.; Hendricks, M.R.; Nieto-Perez, M.

    2009-01-01

    Lithium as a plasma-facing component has many attractive features in fusion devices. We investigated chemical properties of the lithiated graphite surfaces during deposition using X-ray photoelectron spectroscopy and low-energy ion scattering spectroscopy. In this study we try to address some of the known issues during lithium deposition, viz., the chemical state of lithium on graphite substrate, oxide layer formation mechanisms, Li passivation effects over time, and chemical change during exposure of the sample to ambient air. X-ray photoelectron studies indicate changes in the chemical composition with various thickness of lithium on graphite during deposition. An oxide layer formation is noticed during lithium deposition even though all the experiments were performed in ultrahigh vacuum. The metal oxide is immediately transformed into carbonate when the deposited sample is exposed to air.

  3. Lifetime assessment of service-exposed components

    International Nuclear Information System (INIS)

    Kalwa, G.; Weber, H.

    1988-01-01

    A longtime prognosis on the operation of creep-exposed components requires a lifetime analysis. The basis for such an analysis can be improved by an analysis of microstructure and material properties. Actually the grade of material exhaustion has to be regarded as proper assessment quantity. However, stress and time safety also are valuable assessment quantities which should be taken into consideration, especially when the grade of exhaustion is uncertain because of inaccurate input parameters. A correct assessment of the damage state cannot be made without taking into consideration the failure mechanism which has to be assumed for a specific component. With respect to creep the most critical component of a steamline system is the pipe bend because of the risk of large damage events. For this case component metallography by replicas is suggested as preventive test method. The continuation of service of a creep damage pipe bend cannot be recommended. (orig./MM) [de

  4. Exposing the Myths, Defining the Future

    International Nuclear Information System (INIS)

    Slavov, S.

    2013-01-01

    With this official statement, the WEC calls for policymakers and industry leaders to ''get real'' as the World Energy Council as a global energy body exposes the myths by informing the energy debate and defines a path to a more sustainable energy future. The World Energy Council urged stakeholders to take urgent and incisive actions, to develop and transform the global energy system. Failure to do so could put aspirations on the triple challenge of WEC Energy Trilemma defined by affordability, accessibility and environmental sustainability at serious risk. Through its multi-year in-depth global studies and issue-mapping the WEC has found that challenges that energy sector is facing today are much more crucial than previously envisaged. The WEC's analysis has exposed a number of myths which influence our understanding of important aspects of the global energy landscape. If not challenged, these misconceptions will lead us down a path of complacency and missed opportunities. Much has, and still is, being done to secure energy future, but the WEC' s studies reveal that current pathways fall short of delivering on global aspirations of energy access, energy security and environmental improvements. If we are to derive the full economic and social benefits from energy resources, then we must take incisive and urgent action to modify our steps to energy solutions. The usual business approaches are not effective, the business as usual is not longer a solution. The focus has moved from large universal solutions to an appreciation of regional and national contexts and sharply differentiated consumer expectations.(author)

  5. Clinical investigation of proximate exposed group, 1

    International Nuclear Information System (INIS)

    Ito, Chikako; Hasegawa, Kazuyo; Kato, Masafumi; Kumasawa, Toshihiko

    1984-01-01

    In order to investigate effects of the A-bombing on prevalence of diabetes mellitus, follow-up studies were made on 5907 A-bomb survivors who received glucose tolerance test (GTT) during 20 years between 1963 and 1983. The A-bomb survivors were divided into the group A (1899 men and 1165 women exposed within 1.9 km from the hypocenter) and the group B (1725 men and 1118 women exposed 3.0 km or farther from it). Among non-obese survivors, 21.9% and 21.8% were being treated for diabetes mellitus or were evaluated as having diabetic type on GTT in the group A and the group B, respectively; while this was seen in 52.1% of obese survivors in the group A and 49.9% in the group B. There was no difference between the groups. In non-obese survivors, the annual development rate from the normal type to the diabetic type was 0.89% in the group A and 0.65% in the group B; the annual development rate from the borderline type to the diabetic type was 5.73% in the group A and 5.49% in the group B, showing no differences between the groups. The annual development rate from the normal or borderline type to the diabetic type was two times or higher in obese survivors than in non-obese survivors irrespective of exposure status. Regarding the number of diabetic survivors who became non-diabetic type in spite of having no treatment, and prevalence of diabetic complications, no difference was seen between the groups. These results suggest that the A-bombing has scarcely influenced the prevalence of diabetes mellitus and clinical course. (Namekawa, K.)

  6. Remarks on the Schroedinger operator with singular complex potentials

    International Nuclear Information System (INIS)

    Brezis, Haim; Kato, Tosio

    1979-01-01

    To describe this method in a simple case Section 2 begin with real valued potentials. The main results in Section 2 are essentially known. In Section 3 the case of complex potentials is exposed. Schroedinger operators with complex potentials have been studied by Nelson. This results were extended. Here more general singularities are exposed

  7. Towards a public health profession

    DEFF Research Database (Denmark)

    Foldspang, Anders

    2015-01-01

    in the theoretical as well as the practical potential of the public health professional. Thus, he and she must be able to perform, what WHO Europe has developed as Essential Public Health Operations (EPHOs).3 This, in turn, implies that the public health professional possesses the set of intellectual (knowledge...... endorsed by WHO Europe’s member states as the basis for the public health education in Europe.5 The sections of the lists include: Public health methods; Population health and: Its social and economic determinants, and: Its material environmental determinants; Man-made interventions and systems, namely...... Health policy, health economics, organizational theory, health legislation, and public health leadership and management; Health promotion—health education, health protection, disease prevention; public health ethics. This should form the central part of the basis for all public health professionals...

  8. Nasal biopsies of children exposed to air pollutants.

    Science.gov (United States)

    Calderón-Garcidueñas, L; Rodriguez-Alcaraz, A; Valencia-Salazar, G; Mora-Tascareño, A; García, R; Osnaya, N; Villarreal-Calderón, A; Devlin, R B; Van Dyke, T

    2001-01-01

    Southwest Metropolitan Mexico City (SWMMC) atmosphere is a complex mixture of air pollutants, including ozone, particulate matter, and aldehydes. Children in SWMMC are exposed chronically and sequentially to numerous toxicants, and they exhibit significant nasal damage. The objective of this study was to assess p53 accumulation by immunohistochemistry in nasal biopsies of SWMMC children. We evaluated 111 biopsies from 107 children (83 exposed SWMMC children and 24 control children residents in a pollutant-compliant Caribbean island). Complete clinical histories and physical examinations, including an ear-nose-throat (ENT) exam were done. There was a significant statistical difference in the upper and lower respiratory symptomatology and ENT findings between control and exposed children (p < 0.001). Control children gave no respiratory symptomatology in the 3 months prior to the study; their biopsies exhibited normal ciliated respiratory epithelium and were p53-negative. SWMMC children complained of epistaxis, nasal obstruction. and crusting. Irregular areas of whitish-gray recessed mucosa over the inferior and middle turbinates were seen in 25% of SWMMC children, and their nasal biopsies displayed basal cell hyperplasia, decreased numbers of ciliated and goblet cells, neutrophilic epithelial infiltrates, squamous metaplasia. and mild dysplasia. Four of 21 SWMMC children with grossly abnormal mucosal changes exhibited strong transmural nuclear p53 staining in their nasal biopsies (p 0.005, odds ratio 26). In the context of lifetime exposures to toxic and potentially carcinogenic air pollutants, p53 nasal induction in children could potentially represent. a) a checkpoint response to toxic exposures, setting up a selective condition for p53 mutation, or b) a p53 mutation has already occurred as a result of such selection. Because the biological significance of p53 nuclear accumulation in the nasal biopsies of these children is not clear at this point, we strongly

  9. An outbreak of schistosomiasis in travellers returning from endemic areas: the importance of rigorous tracing in peer groups exposed to risk of infection.

    Science.gov (United States)

    Blach, Ola; Rai, Bhavan; Oates, Ken; Franklin, Grant; Bramwell, Steve

    2012-03-01

    Each year, schools across Scotland send their students on exchange programmes to Malawi. Between 2005 and 2009, 22.8% of Scotland's new cases of schistosomiasis were from freshwater exposure in Malawi, with 41.5% diagnosed in 15-24 year olds. In January 2011, a 17-year-old male presented to our urology department with visible haematuria following freshwater exposure during a school trip to Malawi. He was subsequently diagnosed with urinary schistosomiasis. The potential involvement of other individuals from the trip prompted further public health enquiry. The school, public health department and education authorities were notified promptly and all individuals potentially exposed to Schistosoma haematobium were invited for screening. All 21 participants of the exchange programme underwent serological screening. Thirteen tested positive for Schistosoma infection. Only two individuals displayed symptoms of schistosomiasis; the other 11 were asymptomatic. Infection rates, even following a limited exposure to S. haematobium, are high. The majority of seropositive cases may never have symptoms. Therefore, a history of foreign travel to endemic schistosomiasis areas should be sought from any young person presenting with visible heamaturia and appropriate tests instigated. Schools should adopt policies forbidding activities involving freshwater exposure in Malawi. Effective public health measures must be set in place to trace and treat any other possible cases of exposure.

  10. Public-Private Partnership in the EU Public Procurement Regime

    DEFF Research Database (Denmark)

    Andrecka, Marta

    , poses legal challenges for the procurement of PPP contracts. The overall research objective of my doctoral thesis is to analyse, clarify and discuss potential legal challenges resulting from European Union public procurement law - provided in Directive 2004/18/EC – which a public authority is obliged......My PhD research focuses on the relationship between the formation and operation of a Public-Private Partnership (PPP) and public procurement law as a legal framework for the award of the PPP contract. The complex nature of PPP projects including long term high value contracts, long award process...... to apply when awarding a Public-Private Partnership contract, as well as to analyse if a deregulation of PPP’s award framework could potentially resolve these potential legal challenges. The latter consideration of deregulation of PPP award framework is based on comparison of highly regulated European...

  11. 9 CFR 78.8 - Brucellosis exposed cattle.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Brucellosis exposed cattle. 78.8... Restrictions on Interstate Movement of Cattle Because of Brucellosis § 78.8 Brucellosis exposed cattle. Brucellosis exposed cattle may be moved interstate only as follows: (a) Movement to recognized slaughtering...

  12. Going public

    DEFF Research Database (Denmark)

    Meyer, Gitte; Sandøe, Peter

    2012-01-01

    conduct, contains a tacit maxim of openness which may naturally be extended to cover the public relations of science. Discussing openness as access, accountability, transparency and receptiveness, the argumentation concentrates on the possible prevention of misconduct with respect to, on the one hand......The paper addresses issues of scientific conduct regarding relations between science and the media, relations between scientists and journalists, and attitudes towards the public at large. In the large and increasing body of literature on scientific conduct and misconduct, these issues seem...... deal with ethical public relations issues, guided by a norm or maxim of openness. Drawing on and rethinking the CUDOS codification of the scientific ethos, as it was worked out by Robert K. Merton in 1942, we propose that this, which is echoed in current codifications of norms for good scientific...

  13. Public Sphere

    DEFF Research Database (Denmark)

    Trenz, Hans-Jörg

    2015-01-01

    In modern societies, the public sphere represents the intermediary realm that supports the communication of opinions, the discovery of problems that need to be dealt with collectively, the channeling of these problems through the filter of the media and political institutions, and the realization...... of the collective will of the people in the act of democratic self-government. The concept of the public sphere is used across the fields of media and communication research, cultural studies and the humanities, the history of ideas, legal and constitutional studies as well as democracy studies. Historically......, public spheres have undergone structural transformations that were closely connected to the emergence of different mass media. More recently, they are subject to trends of transnationalization and digitalization in politics and society....

  14. Corrupción pública/Public corruption

    Directory of Open Access Journals (Sweden)

    Idalia Patricia Espinosa Leal

    2015-01-01

    Full Text Available The aim of this paper is to explain what you meant by corruption, expose theories, analyze the classifications, manifest expressions of public corruption and institutional review and Mexican federal law used to fight against it.

  15. public spaces

    Directory of Open Access Journals (Sweden)

    Elena Grigoryeva

    2013-01-01

    Full Text Available The topic of this issue is PUBLIC SPACES. It is familiar and clear to every citizen. The streets and courtyards as childhood experiences remain with us forever. And these are the places where we come with our parents at weekends, where we meet friends, where we have dates and where we already come for a walk with our children.The history of public spaces is long and captivating. It was the main city squares where the most important events took place in history. The Agoras of Ancient Greece and the Roman Forums, the squares of Vatican, Paris and London, Moscow and Saint Petersburg… Greve, Trafalgar, Senate, Palace, Red, Bolotnaya – behind every name there is life of capitals, countries and nations.Public spaces, their shapes, image and development greatly influence the perception of the city as a whole. Both visitors and inhabitants can see in public spaces not only the visage but the heart, the soul and the mind of the city.Unfortunately, sometimes we have to prove the value of public spaces and defend them from those who consider them nothing but a blank space, nobody’s land destined for barbarous development.What should happen to make citizens perceive public spaces as their own and to make authorities consider development and maintenance of squares and parks their priority task against the  background of increasing competition between cities and the fight for human capital? Lately they more often say about “a high-quality human capital”. And now, when they say “the city should be liveable” they add “for all groups of citizens, including the creative class”.

  16. Public Performance

    Science.gov (United States)

    Krupp, E. C.

    2013-01-01

    America’s first planetaria all opened in the 1930s, and each was the distinctive product of local circumstances. In Los Angeles, the populist sensibilities of Griffith J. Griffith prompted him to value the transformative power of a personal encounter with a telescope, and he quickly embraced the idea of a public observatory with free access to all. Griffith Observatory and its planetarium emerged from that intent. Authenticity, intelligibility, and theatricality were fundamental principles in Griffith’s thinking, and they were transformed into solid and enduring scientific and astronomical values by those who actually guided the Observatory’s design, construction, and programming. That said, the public profile of Griffith Observatory was most defined by its inspired hilltop location, its distinctive, commanding architecture, and its felicitous proximity to Hollywood. The Observatory is theatric in placement and in appearance, and before the Observatory even opened, it was used as a motion picture set. That continuing vocation turned Griffith Observatory into a Hollywood star. Because entertainment industry objectives and resources were part of the Los Angeles landscape, they influenced Observatory programming throughout the Observatory’s history. Public astronomy in Los Angeles has largely been framed by the Observatory’s fundamental nature. It has exhibits, but it is not a museum. It has a planetarium, but it is essentially an observatory. As a public observatory, it is filled with instruments that transform visitors into observers. This role emphasized the importance of personal experience and established the perception of Griffith Observatory as a place for public gathering and shared contact with the cosmos. The Observatory’s close and continuous link with amateur astronomers made amateurs influential partners in the public enterprise. In full accord with Griffith J. Griffith’s original intent, Griffith Observatory has all been about putting

  17. Cybersecurity Public Sector Threats and Responses

    CERN Document Server

    Andreasson, Kim J

    2011-01-01

    The Internet has given rise to new opportunities for the public sector to improve efficiency and better serve constituents in the form of e-government. But with a rapidly growing user base globally and an increasing reliance on the Internet, digital tools are also exposing the public sector to new risks. An accessible primer, Cybersecurity: Public Sector Threats and Responses focuses on the convergence of globalization, connectivity, and the migration of public sector functions online. It identifies the challenges you need to be aware of and examines emerging trends and strategies from around

  18. Public acceptance

    International Nuclear Information System (INIS)

    Bucaille, A.

    2006-01-01

    Full text of publication follows: A great deal of determination and professionalism are required when communicating to the public on nuclear energy. Challenging the advantages and adopting an educational tone are, of course, essential. But we have to do much more if we truly want to set people thinking and give nuclear energy its rightful position among the possible energy solutions. This is particularly important in Europe where dissension between countries is on the increase, whereas the US and China, shortly to be joined by India, have clearly decided to invest in nuclear energy. (author)

  19. Medical handling of accidentally exposed individuals

    International Nuclear Information System (INIS)

    1988-01-01

    In 1978 the International Atomic Energy Agency issued a publication in the IAEA Safety Series entitled Manual on Early Medical Treatment of Possible Radiation Injury (Safety Series No. 47). The contents were directed to first aid and early medical treatment of workers who might be concerned in an accident involving exposure to radiation, whether external or internal. The present manual is the first of a set of three safety series publications dealing with assessment and treatment of overexposures which will constitute an articulated system of documents covering all aspects of diagnosis, prognosis and treatment of overexposures. This document establishes a set of general criteria and recommendations to aid specialists involved in the medical handling of overexposed persons. It deals with the medical management of individual patients or small groups of patients under close medical supervision. 14 refs, 7 figs, 7 tabs

  20. Deviant ERP Response to Spoken Non-Words among Adolescents Exposed to Cocaine in Utero

    Science.gov (United States)

    Landi, Nicole; Crowley, Michael J.; Wu, Jia; Bailey, Christopher A.; Mayes, Linda C.

    2012-01-01

    Concern for the impact of prenatal cocaine exposure (PCE) on human language development is based on observations of impaired performance on assessments of language skills in these children relative to non-exposed children. We investigated the effects of PCE on speech processing ability using event-related potentials (ERPs) among a sample of…

  1. Radiation surveillance of exposed workers during activities of moving of the earth area of Montecillo

    International Nuclear Information System (INIS)

    Ortiz, M. T.; Alvarez, A.; Garcia, E.; Diaz, P.; Quinones, J.

    2013-01-01

    One of the objectives of this study was to limit the doses received by exposed workers and the public (in this case the workers of the CIEMATs buildings next to the work) by setting the appropriate criteria of optimization and protection.In addition was a theoretical evaluation of the dose inhalation, workers would have received if ALARA study protection measures has not been established. (Author)

  2. Hemoglobinopatias em trabalhadores expostos à riscos ocupacionais Hemoglobinopathies in workers exposed to occupational hazards

    Directory of Open Access Journals (Sweden)

    Isaac L. Silva Filho

    2002-12-01

    Full Text Available Hemoglobinopathies have been considered the most frequent hereditary disease in Brazilian population, constituting a Public Health problem. This paper reports on screening in workers at FIOCRUZ-RJ., exposed to some hazards factors such as, chemical substances, radiation, excessive cold and heat etc., with the objective of evaluating the impact of these factors in carriers of hemoglobinopathies, mainly in sickle cell trait (AS.

  3. Inventory of MRI applications and workers exposed to MRI-related electromagnetic fields in the Netherlands

    Energy Technology Data Exchange (ETDEWEB)

    Schaap, Kristel; Christopher-De Vries, Yvette; Slottje, Pauline; Kromhout, Hans, E-mail: h.kromhout@uu.nl

    2013-12-01

    Objective: This study aims to characterise and quantify the population that is occupationally exposed to electromagnetic fields (EMF) from magnetic resonance imaging (MRI) devices and to identify factors that determine the probability and type of exposure. Materials and methods: A questionnaire survey was used to collect information about scanners, procedures, historical developments and employees working with or near MRI scanners in clinical and research MRI departments in the Netherlands. Results: Data were obtained from 145 MRI departments. A rapid increase in the use of MRI and field strength of the scanners was observed and quantified. The strongest magnets were employed by academic hospitals and research departments. Approximately 7000 individuals were reported to be working inside an MRI scanner room and were thus considered to have high probability of occupational exposure to static magnetic fields (SMF). Fifty-four per cent was exposed to SMF at least one day per month. The largest occupationally exposed group were radiographers (n ∼ 1700). Nine per cent of the 7000 involved workers were regularly present inside a scanner room during image acquisition, when exposure to additional types of EMF is considered a possibility. This practice was most prevalent among workers involved in scanning animals. Conclusion: The data illustrate recent trends and historical developments in magnetic resonance imaging and provide an extensive characterisation of the occupationally exposed population. A considerable number of workers are potentially exposed to MRI-related EMF. Type and frequency of potential exposure depend on the job performed, as well as the type of workplace.

  4. Study of the thorium incorporation by inhalation in individuals occupationally exposed

    International Nuclear Information System (INIS)

    Holanda e Vasconcellos Carvalho, B. de.

    1983-01-01

    A mathematical model describing the metabolism of inhaled thorium in the human body was developed. Through this model theoretical limits of excretion were calculated for workers of a monazite plant (Usina Santo Amaro). This limits were based on International Commission on Radiological Protection publication 30, 1979. Excreta samples from twelve workers of Usina Santo Amaro were collected and analysed for thorium. All samples were bellow the theoretical limits of excretion indicating that Usina Santo Amaro workers are exposed to thorium levels bellow the Annual Limits of Intake recommended by ICRP, publication 30. (author)

  5. Influence of Personal Factors on Sound Perception and Overall Experience in Urban Green Areas. A Case Study of a Cycling Path Highly Exposed to Road Traffic Noise

    Directory of Open Access Journals (Sweden)

    Francesco Aletta

    2018-05-01

    Full Text Available In contemporary urban design, green public areas play a vital role. They have great societal value, but if exposed to undue environmental noise their restorative potential might be compromised. On the other hand, research has shown that the presence of greenery can moderate noise annoyance in areas with high sound levels, while personal factors are expected to play an important role too. A cycling path bordered by vegetation, but highly exposed to road traffic noise, was here considered as a case study. A sound perception survey was submitted to participants on site and they were subsequently sorted into groups according to their noise sensitivity, visual attention and attitude towards greenery. The aim of this study was testing whether these three personal factors could affect their noise perception and overall experience of the place. Results showed that people highly sensitive to noise and more sceptical towards greenery’s potential as an environmental moderator reported worse soundscape quality, while visually attentive people reported better quality. These three personal factors were found to be statistically independent. This study shows that several person-related factors impact the assessment of the sound environment in green areas. Although the majority of the respondents benefit from the presence of visual green, policy-makers and planners should be aware that for a significant subset of the population, it should be accompanied by a tranquil soundscape to be fully appreciated.

  6. Influence of Personal Factors on Sound Perception and Overall Experience in Urban Green Areas. A Case Study of a Cycling Path Highly Exposed to Road Traffic Noise.

    Science.gov (United States)

    Aletta, Francesco; Van Renterghem, Timothy; Botteldooren, Dick

    2018-05-30

    In contemporary urban design, green public areas play a vital role. They have great societal value, but if exposed to undue environmental noise their restorative potential might be compromised. On the other hand, research has shown that the presence of greenery can moderate noise annoyance in areas with high sound levels, while personal factors are expected to play an important role too. A cycling path bordered by vegetation, but highly exposed to road traffic noise, was here considered as a case study. A sound perception survey was submitted to participants on site and they were subsequently sorted into groups according to their noise sensitivity, visual attention and attitude towards greenery. The aim of this study was testing whether these three personal factors could affect their noise perception and overall experience of the place. Results showed that people highly sensitive to noise and more sceptical towards greenery's potential as an environmental moderator reported worse soundscape quality, while visually attentive people reported better quality. These three personal factors were found to be statistically independent. This study shows that several person-related factors impact the assessment of the sound environment in green areas. Although the majority of the respondents benefit from the presence of visual green, policy-makers and planners should be aware that for a significant subset of the population, it should be accompanied by a tranquil soundscape to be fully appreciated.

  7. Public health

    NARCIS (Netherlands)

    Berg, van den A.E.

    2007-01-01

    Agnes van den Berg wrote an essay about human health and nature, establishing that subject as an important policy argument in developing (urban) nature in the Netherlands. She studied the public balance of fear and fascination for nature, summarising benefits on human health. In this chapter, she

  8. Representatives of the Public?

    DEFF Research Database (Denmark)

    Rasmussen, Anne; Carroll, Brendan; Lowery, David

    2014-01-01

    Although scholars have long speculated about how organised interests link the public to decision makers, there has actually been little empirical research on this important element of democratic theory. This important gap in the literature is addressed in this article by examining, in addition...... to other supply-side and demand-side factors, whether groups mobilise on issues in policy areas that are regarded as salient by the public. Based on an analysis of 4,501 contributions in 142 European Commission online consultations, it is found that organised interests potentially can act as a transmission...

  9. Biological monitoring results for cadmium exposed workers.

    Science.gov (United States)

    McDiarmid, M A; Freeman, C S; Grossman, E A; Martonik, J

    1996-11-01

    As part of a settlement agreement with the Occupational Safety and Health Administration (OSHA) involving exposure to cadmium (Cd), a battery production facility provided medical surveillance data to OSHA for review. Measurements of cadmium in blood, cadmium in urine, and beta 2-microglobulin in urine were obtained for more than 100 workers over an 18-month period. Some airborne Cd exposure data were also made available. Two subpopulations of this cohort were of primary interest in evaluating compliance with the medical surveillance provisions of the Cadmium Standard. These were a group of 16 workers medically removed from cadmium exposure due to elevations in some biological parameter, and a group of platemakers. Platemaking had presented a particularly high exposure opportunity and had recently undergone engineering interventions to minimize exposure. The effect on three biological monitoring parameters of medical removal protection in the first group and engineering controls in platemakers is reported. Results reveal that both medical removal from cadmium exposures and exposure abatement through the use of engineering and work practice controls generally result in declines in biological monitoring parameters of exposed workers. Implications for the success of interventions are discussed.

  10. Exposing the “One China” Principle

    Directory of Open Access Journals (Sweden)

    Chien-yuan Tseng

    2016-12-01

    Full Text Available In 1992, when the governments from both sides across the Taiwan Strait began having contacts, both of them, at the People’s Republic of China (PRC’s request, expressed verbally, and in relation to functional issues, that they advocated the “one China” principle, though what “one China” actually meant was open to different interpretations, and the shift that elevated the 1992 “one China” interpretations from the functional level to the political level did not occur until April 2005. Since President Tsai Ing-wen was sworn in and the Democratic Progressive Party (DPP became the ruling party of the Republic of China (ROC on Taiwan in early 2016, the PRC has used Tsai’s rejection of this so-called “1992 consensus” as a pretext to discontinue all intergovernmental communication channels with the ROC on Taiwan, while also cutting down on cross-strait civil exchanges in travel and education. This thinkpiece article aims to scrutinise this “one China” principle, how it has developed over the years, and expose its underlying realities.

  11. Sociodemographic variations in the amount, duration and cost of potentially preventable hospitalisation for chronic conditions among Aboriginal and non-Aboriginal Australians: a period prevalence study of linked public hospital data.

    Science.gov (United States)

    Banham, David; Chen, Tenglong; Karnon, Jonathan; Brown, Alex; Lynch, John

    2017-10-15

    To determine disparities in rates, length of stay (LOS) and hospital costs of potentially preventable hospitalisations (PPH) for selected chronic conditions among Aboriginal and non-Aboriginal South Australians (SA), then examine associations with area-level socioeconomic disadvantage and remoteness. Period prevalence study using linked, administrative public hospital records. Participants included all SA residents in 2005-2006 to 2010-2011. Analysis focused on those individuals experiencing chronic PPH as defined by the Australian Institute of Health and Welfare. Number and rates (unadjusted, then adjusted for sex and age) of chronic PPH, total LOS and direct hospital costs by Aboriginality. Aboriginal SAs experienced higher risk of index chronic PPH compared with non-Aboriginals (11.5 and 6.2 per 1000 persons per year, respectively) and at younger ages (median age 48 vs 70 years). Once hospitalised, Aboriginal people experienced more chronic PPH events, longer total LOS with higher costs than non-Aboriginal people (2.6 vs 1.9 PPH per person; 11.7 vs 9.0 days LOS; at $A17 928 vs $A11 515, respectively). Compared with population average LOS, the standardised rate ratio of LOS among Aboriginal people increased by 0.03 (95% CI 0.00 to 0.07) as disadvantage rank increased and 1.04 (95% CI 0.63 to 1.44) as remoteness increased. Non-Aboriginal LOS also increased as disadvantage increased but at a lower rate (0.01 (95% CI 0.01 to 0.01)). Costs of Aboriginal chronic PPH increased by 0.02 (95% CI 0.00 to 0.06) for each increase in disadvantage and 1.18 (95% CI 0.80 to 1.55) for increased remoteness. Non-Aboriginal costs also increased as disadvantage increased but at lower rates (0.01 (95% CI 0.01 to 0.01)). Aboriginal people's heightened risk of chronic PPH resulted in more time in hospital and greater cost. Systematic disparities in chronic PPH by Aboriginality, area disadvantage and remoteness highlight the need for improved uptake of effective primary care. Routine

  12. Right To Public Information Regulation In Mexico

    Directory of Open Access Journals (Sweden)

    Carlos Manuel Rosales García

    2013-01-01

    Full Text Available This paper exposes the legal nature and the usefulness of the right to information, is special in the case of Mexico. So it will be a study of the right to public information, in order to understand its origin and utility; then analyze the establishment and evolution in Mexican positive and discover its use as a mechanism for transparent use of public resources and the accountability of the State authorities.

  13. Toxicological assessments of rats exposed prenatally to inhaled vapors of gasoline and gasoline-ethanol blends.

    Science.gov (United States)

    Bushnell, Philip J; Beasley, Tracey E; Evansky, Paul A; Martin, Sheppard A; McDaniel, Katherine L; Moser, Virginia C; Luebke, Robert W; Norwood, Joel; Copeland, Carey B; Kleindienst, Tadeusz E; Lonneman, William A; Rogers, John M

    2015-01-01

    The primary alternative to petroleum-based fuels is ethanol, which may be blended with gasoline in the United States at concentrations up to 15% for most automobiles. Efforts to increase the amount of ethanol in gasoline have prompted concerns about the potential toxicity of inhaled ethanol vapors from these fuels. The well-known sensitivity of the developing nervous and immune systems to ingested ethanol and the lack of information about the neurodevelopmental toxicity of ethanol-blended fuels prompted the present work. Pregnant Long-Evans rats were exposed for 6.5h/day on days 9-20 of gestation to clean air or vapors of gasoline containing no ethanol (E0) or gasoline blended with 15% ethanol (E15) or 85% ethanol (E85) at nominal concentrations of 3000, 6000, or 9000 ppm. Estimated maternal peak blood ethanol concentrations were less than 5mg/dL for all exposures. No overt toxicity in the dams was observed, although pregnant dams exposed to 9000 ppm of E0 or E85 gained more weight per gram of food consumed during the 12 days of exposure than did controls. Fuel vapors did not affect litter size or weight, or postnatal weight gain in the offspring. Tests of motor activity and a functional observational battery (FOB) administered to the offspring between post-natal day (PND) 27-29 and PND 56-63 revealed an increase in vertical activity counts in the 3000- and 9000-ppm groups in the E85 experiment on PND 63 and a few small changes in sensorimotor responses in the FOB that were not monotonically related to exposure concentration in any experiment. Neither cell-mediated nor humoral immunity were affected in a concentration-related manner by exposure to any of the vapors in 6-week-old male or female offspring. Systematic concentration-related differences in systolic blood pressure were not observed in rats tested at 3 and 6 months of age in any experiment. No systematic differences were observed in serum glucose or glycated hemoglobin A1c (a marker of long-term glucose

  14. Exposing region duplication through local geometrical color invariant features

    Science.gov (United States)

    Gong, Jiachang; Guo, Jichang

    2015-05-01

    Many advanced image-processing softwares are available for tampering images. How to determine the authenticity of an image has become an urgent problem. Copy-move is one of the most common image forgery operations. Many methods have been proposed for copy-move forgery detection (CMFD). However, most of these methods are designed for grayscale images without any color information used. They are usually not suitable when the duplicated regions have little structure or have undergone various transforms. We propose a CMFD method using local geometrical color invariant features to detect duplicated regions. The method starts by calculating the color gradient of the inspected image. Then, we directly take the color gradient as the input for scale invariant features transform (SIFT) to extract color-SIFT descriptors. Finally, keypoints are matched and clustered before their geometrical relationship is estimated to expose the duplicated regions. We evaluate the detection performance and computational complexity of the proposed method together with several popular CMFD methods on a public database. Experimental results demonstrate the efficacy of the proposed method in detecting duplicated regions with various transforms and poor structure.

  15. End stage renal disease among ceramic workers exposed to silica.

    Science.gov (United States)

    Rapiti, E; Sperati, A; Miceli, M; Forastiere, F; Di Lallo, D; Cavariani, F; Goldsmith, D F; Perucci, C A

    1999-08-01

    To evaluate whether ceramic workers exposed to silica experience an excess of end stage renal disease. On the basis of a health surveillance programme, a cohort of 2980 male ceramic workers has been enrolled during the period 1974-91 in Civitacastellana, Lazio, Italy. For each worker, employment history, smoking data, and x ray film readings were available. The vital status was ascertained for all cohort members. All 2820 people still alive and resident in the Lazio region as in June 1994 were searched for a match in the regional end stage renal diseases registry, which records (since June, 1994) all patients undergoing dialysis treatment in public and private facilities of the region. Expected numbers of prevalent cases from the cohort were computed by applying the rate of patients on dialysis treatment by the age distribution of the cohort. A total of six cases was detected when 1.87 were expected (observed/expected (O/E) = 3.21; 95% confidence interval (95% CI) 1.17 to 6.98). The excess risk was present among non-smokers (O = 2; O/E = 4.34) and smokers (O = 4; O/E = 2.83), as well as among workers without silicosis (O = 4; O/E = 2.78) and workers with silicosis (O = 2; O/E = 4.54). The risk was higher among subjects with 20 years. These results provide further evidence that exposure to silica dust among ceramic workers is associated with nephrotoxic effects.

  16. A decision model for intergenerational life-cycle risk assessment of civil infrastructure exposed to hurricanes under climate change

    International Nuclear Information System (INIS)

    Lee, Ji Yun; Ellingwood, Bruce R.

    2017-01-01

    Public awareness of civil infrastructure performance has increased considerably in recent years as a result of repeated natural disasters. Risks from natural hazards may increase dramatically in the future, given current patterns of urbanization and population growth in hazard-prone areas. Risk assessments for infrastructure with expected service periods of a century or more are highly uncertain, and there is compelling evidence that climatology will evolve over such intervals. Thus, current natural hazard and risk assessment models, which are based on a presumption of stationarity in hazard occurrence and intensity, may not be adequate to assess the potential risks from hazards occurring in the distant future. This paper addresses two significant intergenerational elements – the potential impact of non-stationarity in hazard due to climate change and intergenerational discounting practices – that are essential to provide an improved decision support framework that accommodates the needs and values of future generations. The framework so developed is tested through two benchmark problems involving buildings exposed to hurricanes. - Highlights: • Difficulties of conventional life-cycle engineering decision-making over multiple generations are clearly elaborated. • Two intergenerational elements are proposed to reflect equitable allocations of risk between generations. • A data-based approach to forecast future hurricanes is provided to bridge the gap between models at large and local scales. • The feasibility and practicability of a refined framework are examined through two lifecycle cost assessment examples. • The two intergenerational elements suggested in this study have a wide range of applicability.

  17. Genotoxic damage in pathology anatomy laboratory workers exposed to formaldehyde

    International Nuclear Information System (INIS)

    Costa, Solange; Coelho, Patricia; Costa, Carla; Silva, Susana; Mayan, Olga; Silva Santos, Luis; Gaspar, Jorge; Teixeira, Joao Paulo

    2008-01-01

    Formaldehyde (FA) is a chemical traditionally used in pathology and anatomy laboratories as a tissue preservative. Several epidemiological studies of occupational exposure to FA have indicated an increased risk of nasopharyngeal cancers in industrial workers, embalmers and pathology anatomists. There is also a clear evidence of nasal squamous cell carcinomas from inhalation studies in the rat. The postulated mode of action for nasal tumours in rats was considered biologically plausible and considered likely to be relevant to humans. Based on the available data IARC, the International Agency for Research on Cancer, has recently classified FA as a human carcinogen. Although the in vitro genotoxic as well as the in vivo carcinogenic potentials of FA are well documented in mammalian cells and in rodents, evidence for genotoxic effects and carcinogenic properties in humans is insufficient and conflicting thus remains to be more documented. To evaluate the genetic effects of long-term occupational exposure to FA a group of 30 Pathological Anatomy laboratory workers was tested for a variety of biological endpoints, cytogenetic tests (micronuclei, MN; sister chromatid exchange, SCE) and comet assay. The level of exposure to FA was evaluated near the breathing zone of workers, time weighted average of exposure was calculated for each subject. The association between the biomarkers and polymorphic genes of xenobiotic metabolising and DNA repair enzymes was also assessed. The mean level of exposure was 0.44 ± 0.08 ppm (0.04-1.58 ppm). MN frequency was significantly higher (p = 0.003) in the exposed subjects (5.47 ± 0.76) when compared with controls (3.27 ± 0.69). SCE mean value was significantly higher (p < 0.05) among the exposed group (6.13 ± 0.29) compared with control group (4.49 ± 0.16). Comet assay data showed a significant increase (p < 0.05) of TL in FA-exposed workers (60.00 ± 2.31) with respect to the control group (41.85 ± 1.97). A positive correlation was

  18. Influence of Concussion History and Genetics on Event-Related Potentials in Athletes: Potential Use in Concussion Management

    Directory of Open Access Journals (Sweden)

    Taylor Guth

    2018-01-01

    Full Text Available Sports-related concussions are an increasing public health issue with much concern about the possible long-term decrements in cognitive function and quality of life that may occur in athletes. The measurement of cognitive function is a common component of concussion management protocols due to cognitive impairments that occur after sustaining a concussion; however, the tools that are often used may not be sensitive enough to expose long term problems with cognitive function. The current paper is a brief review, which suggests that measuring cognitive processing through the use of event related potentials (ERPs may provide a more sensitive assessment of cognitive function, as shown through recent research showing concussion history to influence ERPs components. The potential influence of genetics on cognitive function and ERPs components will also be discussed in relation to future concussion management.

  19. Measuring transparency in public spending: Case of Czech public e-procurement information system

    OpenAIRE

    Chvalkovská, Jana; Skuhrovec, Jiří

    2010-01-01

    The objective of this paper is to analyze the potential of e-Government tools to enable the general public to oversee spending of public institutions. The paper illustrates the “watchdog” potential of reducing corruption by means of providing information to the public on the example of the Czech Public e-Procurement Information System (further called System). The System is an Internet portal, where public authorities announce their intention to purchase goods and services. Such announcements ...

  20. Viability and Virulence of Entomopathogenic Nematodes Exposed to Ultraviolet Radiation.

    Science.gov (United States)

    Shapiro-Ilan, David I; Hazir, Selcuk; Lete, Luis

    2015-09-01

    Entomopathogenic nematodes (EPNs) can be highly effective biocontrol agents, but their efficacy can be reduced due to exposure to environmental stress such as from ultraviolet (UV) radiation. Our objectives were to 1) compare UV tolerance among a broad array of EPN species, and 2) investigate the relationship between reduced nematode viability (after exposure to UV) and virulence. Nematodes exposed to a UV radiation (254 nm) for 10 or 20 min were assessed separately for viability (survival) and virulence to Galleria mellonella. We compared 9 different EPN species and 15 strains: Heterorhabditis bacteriophora (Baine, fl11, Oswego, and Vs strains), H. floridensis (332), H. georgiana (Kesha), H. indica (HOM1), H. megidis (UK211), Steinernema carpocapsae (All, Cxrd, DD136, and Sal strains), S. feltiae (SN), S. rarum (17C&E), and S. riobrave (355). In viability assessments, steinernematids, particularly strains of S. carpocapsae, generally exhibited superior UV tolerance compared with the heterorhabditids. However, some heterorhabditids tended to be more tolerant than others, e.g., H. megidis and H. bacteriophora (Baine) were most susceptible and H. bacteriophora (Vs) was the only heterorhabditid that did not exhibit a significant effect after 10 min of exposure. All heterorhabditids experienced reduced viability after 20 min exposure though several S. carpocapsae strains did not. In total, after 10 or 20 min exposure, the viability of seven nematode strains did not differ from their non-UV exposed controls. In virulence assays, steinernematids (particularly S. carpocapsae strains) also tended to exhibit higher UV tolerance. However, in contrast to the viability measurements, all nematodes experienced a reduction in virulence relative to their controls. Correlation analysis revealed that viability among nematode strains is not necessarily related to virulence. In conclusion, our results indicate that the impact of UV varies substantially among EPNs, and viability alone

  1. Crescimento, trocas gasosas e potencial osmótico da bananeira-'Prata', submetida a diferentes doses de sódio e cálcio em solução nutritiva Growth, gaseous exchange and osmotic potential of banana 'Prata' plants, exposed to different concentrations of sodium and calcium in nutritive solution

    Directory of Open Access Journals (Sweden)

    LUDMILA LAFETÁ DE MELO NEVES

    2002-08-01

    Full Text Available O cálcio vem sendo utilizado com o intuito de incrementar tolerância a sais nas plantas, pois sabe-se que a salinidade restringe o crescimento e a produtividade de muitas culturas. Este estudo teve por objetivo avaliar os efeitos da aplicação de sódio e cálcio sobre o crescimento inicial, trocas gasosas e potencial osmótico da bananeira (Musa spp. 'Prata' (AAB. Foi utilizado o delineamento experimental em blocos casualizados, com arranjo fatorial 4 x 4 [ 4 doses de sódio ( 0; 5; 10; 15 mmol L-1 e 4 de cálcio ( 2; 4; 8; 12 mmol L-1] e 3 repetições. A emissão total de folhas e o potencial osmótico das plantas não foram influenciados pelos tratamentos. O aumento dos níveis de sódio na solução promoveu redução significativa na massa fresca da parte aérea, altura, área foliar, diâmetro do pseudocaule e massa seca das plantas. A presença de 5 mmol L-1 de Na na solução favoreceu as trocas gasosas. O aumento dos níveis de cálcio na solução promoveu a redução da massa fresca da parte aérea, altura e área foliar da bananeira-'Prata'.The Calcium has been used to increase salt tolerance in plants since salinity restricts growth and productivity in many crops. This study was conducted with the objective of evaluating the effects of sodium and calcium application on the initial growth, gaseous exchange and osmotic potential of banana (Musa spp. 'Prata' plants (AAB. The experimental layout was a 4 x 4 factorial with three replicates in a randomized complete block design. The factors tested were concentrations of sodium (0; 5; 10; 15 mmol L-1 and calcium (2; 4; 8; 12 mmol L-1. The total emition of leaves and the osmotic potential of the plants were not influenced by the treatments. However, the increase in concentrations of sodium in the nutritive solution resulted in significant reduction of the fresh weight of aerial plant parts, height and leaf area of the plants, diameter of the pseudostem, and dry weight of the plants. The

  2. Public meetings

    CERN Multimedia

    Staff Association

    2012-01-01

    MARS PENSIONS CONTRACT POLICY GENERAL INFORMATION   PUBLIC MEETINGS COME AND BE INFORMED! Public meetings Monday 15 Oct. 2 pm Amphi IT, 31-3-004 Meyrin Wednesday 17 Oct. 10 am Amphi BE, 864-1-D02 Prévessin Thursday 18 Oct. 10 am Salle du Conseil/ Council Chamber 503-1-001 Meyrin Thursday 18 Oct. 2 pm Filtration Plant, 222-R-001(in English) Meyrin   Overview of the topics to be discussed Recognition of Merit – MARS Outcome of last exercise 2007 to 2012 : lessons learned Pension Fund Capital preservation policy : what is it ? Contract policy LC2IC statistics SA proposal General information CVI 2013 Voluntary programmes (PRP, SLS)  

  3. Publications, 1977

    International Nuclear Information System (INIS)

    Hilborn, H.S.

    1978-02-01

    A compilation of documents that communicate the results of scientific and technical work done at Savannah River is given. The compilation includes those documents that have been published (research and development reports, journal articles, book chapters, etc.), documents that have been announced in Energy Research Abstracts, and papers that have been presented at technical meetings but have not yet been published or announced. The information was compiled by machine methods to produce bibliographic, subject, and author listings. This report updates the information included in DP-929, Rev. 2, Publications, 1951 through 1971 and DP-929-1, Publications, 1972 through 1976. The bibliographic listing is arranged alphabetically by the first-mentioned author of each document. Author and subject indexes are provided

  4. Public relations

    International Nuclear Information System (INIS)

    1996-01-01

    At Nuclear Regulatory Authority of the Slovak Republic (NRA SR), the public relations belongs to the secretariat of the Chairman, and are a part of the policy of carefully planned and purposeful efforts to establish mutual relations between the authority and the public. A spokesmen of NRA SR is in charge of the public relations. The spokesman is ready, without a useless filibuster and based on a particular requirement, to inform governmental bodies, other national bodies and organizations, embassies and international organizations, the public and news media in case of an event at a nuclear installation. To provide for communications activities, NRA SR constructed and opened the Information centre with a particular equipment in autumn 1995, that has already started communications with some dailies, broadcasting, television and Press Agency SR. It has been envisaged that there will be press conferences held in the Information centre a few times a year, or NRA SR senior staff may be interviewed here on extraordinary events at NPPs, or on some other important occasions in NRA SR. In 1995, NRA Sr issued the Annual report in a few variants - each suitable for different use - on NRA SR activities and nuclear safety of Slovak nuclear power plants as of 1994. The NRA SR's Bulletin has started to be published with periodicity of 3 times a year, focusing on NRA SR activities both in Slovakia and abroad. NRA SR Information centre provides foreign visitors with independent propagation and information materials about the issue of nuclear safety enhancement at operational Slovak NPPs. Furthermore, the Information centre provides both the NRA SR's residences in Bratislava and Trnava with daily press monitoring of topical news

  5. Brainstem Auditory Evoked Potential in HIV-Positive Adults.

    Science.gov (United States)

    Matas, Carla Gentile; Samelli, Alessandra Giannella; Angrisani, Rosanna Giaffredo; Magliaro, Fernanda Cristina Leite; Segurado, Aluísio C

    2015-10-20

    To characterize the findings of brainstem auditory evoked potential in HIV-positive individuals exposed and not exposed to antiretroviral treatment. This research was a cross-sectional, observational, and descriptive study. Forty-five HIV-positive individuals (18 not exposed and 27 exposed to the antiretroviral treatment - research groups I and II, respectively - and 30 control group individuals) were assessed through brainstem auditory evoked potential. There were no significant between-group differences regarding wave latencies. A higher percentage of altered brainstem auditory evoked potential was observed in the HIV-positive groups when compared to the control group. The most common alteration was in the low brainstem. HIV-positive individuals have a higher percentage of altered brainstem auditory evoked potential that suggests central auditory pathway impairment when compared to HIV-negative individuals. There was no significant difference between individuals exposed and not exposed to antiretroviral treatment.

  6. Degradation of HEPA filters exposed to DMSO

    International Nuclear Information System (INIS)

    Bergman, W.; Wilson, K.; Larsen, G.; Lopez, R.; LeMay, J.

    1994-01-01

    Dimethyl sulfoxide (DMSO) sprays are being used to remove the high explosive (HE) from nuclear weapons in the process of their dismantlement. A boxed 50 cfm HEPA filter with an integral prefilter was exposed to DMSO vapor and aerosols that were generated by a spray nozzle to simulate conditions expected in the HE dissolution operation. After 198 hours of operation, the pressure drop of the filter had increased from 1.15 inches to 2.85 inches, and the efficiency for 0.3 μm dioctyl sebacate (DOS) aerosols decreased from 99.992% to 98.6%. Most of the DMSO aerosols had collected as a liquid pool inside the boxed HEPA. The liquid was blown out of the filter exit with 100 cfm air flow at the end of the test. Since the filter still met the minimum allowed efficiency of 99.97% after 166 hours of exposure, we recommend replacing the filter every 160 hours of operation or sooner if the pressure drop increases by 50%. Examination of the filter showed that visible cracks appeared at the joints of the wooden frame and a portion of the sealant had pulled away from the frame. Since all of the DMSO will be trapped in the first HEPA filter, the second HEPA filter should not suffer from DMSO degradation. Thus the combined efficiency for the first filter (98.6%) and the second filter (99.97%) is 99.99996% for 0.3μm particles. If the first filter is replaced prior to its degradation, each of the filters will have 99.97% efficiency, and the combined efficiency will be 99.999991%. The collection efficiency for DMSO/HE aerosols will be much higher because the particle size is much greater

  7. Degradation of HEPA filters exposed to DMSO

    Energy Technology Data Exchange (ETDEWEB)

    Bergman, W.; Wilson, K.; Larsen, G. [Lawrence Livermore National Laboratory, CA (United States)] [and others

    1995-02-01

    Dimethyl sulfoxide (DMSO) sprays are being used to remove the high explosive (HE) from nuclear weapons in the process of their dismantlement. A boxed 50 cmf HEPA filter with an integral prefilter was exposed to DMSO vapor and aerosols that were generated by a spray nozzle to simulate conditions expected in the HE dissolution operation. After 198 hours of operation, the pressure drop of the filter had increased form 1.15 inches to 2,85 inches, and the efficiency for 0.3 {mu}m dioctyl sebacate (DOS) aerosols decreased form 99.992% to 98.6%. Most of the DMSO aerosols had collected as a liquid pool inside the boxed HEPA. The liquid was blown out of the filter exit with 100 cmf air flow at the end of the test. Since the filter still met the minimum allowed efficiency of 99.97% after 166 hours of exposure, we recommend replacing the filter every 160 hours of operation or sooner if the pressure drop increases by 50%. Examination of the filter showed that visible cracks appeared at the joints of the wooden frame and a portion of the sealant had pulled away from the frame. Since all of the DMSO will be trapped in the first HEPA filter, the second HEPA filter should not suffer from DMSO degradation. Thus the combined efficiency for the first filter (98.6%) and the second filter (99.97%) is 99.99996% for 0.3 {mu}m particles. If the first filter is replaced prior to its degradation, each of the filters will have 99.97% efficiency, and the combined efficiency will be 99.999991%. The collection efficiency for DMSO/HE aerosols will be much higher because the particle size is much greater.

  8. Violent Victimization Among Disadvantaged Young Adults Exposed to Early Family Conflict and Abuse: A 24-Year Prospective Study of the Victimization Cycle Across Gender.

    Science.gov (United States)

    Voith, Laura A; Topitzes, James; Reynolds, Arthur J

    2016-01-01

    Significant associations between childhood victimization and later revictimization have materialized in previous literature; yet, the victimization cycle has been primarily explored with indicators of sexual assault, although insight into linkages between other forms of victimization remains limited. This study examined connections from family conflict exposure and physical abuse in childhood to violent crime victimization in adulthood, assessing also gender differences and neighborhood influences. Results from logistic regression and hierarchical linear modeling with data from the Chicago Longitudinal Study, a panel of 1,539 low-income, ethnic/racial minority children, unearthed a significant relation between family conflict exposure and later revictimization. Moderated by gender, these analyses showed girls exposed to frequent family conflict are particularly vulnerable to revictimization in adulthood. Exploratory analyses unveiled a potential linkage between childhood physical abuse and later revictimization for men. Neighborhood effects marginally influenced results in one instance. Public health implications are discussed.

  9. Modulation of neurological related allergic reaction in mice exposed to low-level toluene

    International Nuclear Information System (INIS)

    Tin-Tin-Win-Shwe; Yamamoto, Shoji; Nakajima, Daisuke; Furuyama, Akiko; Fukushima, Atsushi; Ahmed, Sohel; Goto, Sumio; Fujimaki, Hidekazu

    2007-01-01

    The contributing role of indoor air pollution to the development of allergic disease has become increasingly evident in public health problems. It has been reported that extensive communication exists between neurons and immune cells, and neurotrophins are molecules potentially responsible for regulating and controlling this neuroimmune crosstalk. The adverse effects of volatile organic compounds which are main indoor pollutants on induction or augmentation of neuroimmune interaction have not been fully characterized yet. To investigate the effects of low-level toluene inhalation on the airway inflammatory responses, male C3H mice were exposed to filtered air (control), 9 ppm, and 90 ppm toluene for 30 min by nose-only inhalation on Days 0, 1, 2, 7, 14, 21, and 28. Some groups of mice were injected with ovalbumin intraperitoneally before starting exposure schedule and these mice were then challenged with aerosolized ovalbumin as booster dose. For analysis of airway inflammation, bronchoalveolar lavage (BAL) fluid were collected to determine inflammatory cell influx and lung tissue and blood samples were collected to determine cytokine and neurotrophin mRNA and protein expressions and plasma antibody titers using real-time RT-PCR and ELISA methods respectively. Exposure of the ovalbumin-immunized mice to low-level toluene resulted in (1) increased inflammatory cells infiltration in BAL fluid; (2) increased IL-5 mRNA, decreased nerve growth factor receptor tropomyosin-related kinase A and brain-derived neurotrophic factor mRNAs in lung; and (3) increased IgE and IgG 1 antibodies and nerve growth factor content in the plasma. These findings suggest that low-level toluene exposure aggravates the airway inflammatory responses in ovalbumin-immunized mice by modulating neuroimmune crosstalk

  10. Monitoring of genotoxic effects in lymphocytes of people exposed to pesticides

    International Nuclear Information System (INIS)

    Panek, A.; Marcos, R.; Cebulska-Wasilewska, A.

    2002-01-01

    The aim of this study was to assess the potential genotoxic risk of occupational exposure to pesticides. The DNA damage and the repair capacities of lymphocytes, in four groups of the people of various countries were assessed by the use of single cell gel electrophoresis (SCGE) also known as the Comet assay. The results from the analysis performed in the Spanish group are presented in this paper. Statistical analysis of the results shows a slightly higher level of the DNA damage in the untreated lymphocytes of donors from the group exposed to pesticides; however, only for donors below 30 years old are these differences significant (p<0.05). Although, comparison of the efficiency of the UV-C induced dimmers excision process did not indicate differences between exposed and referent groups, though lymphocytes for donors exposed to pesticides have shown a statistically lower repair rate (p<0.01) than lymphocytes from the unexposed group. (author)

  11. How Public Is Public Administration? A Constitutional Approach of Publicness

    Science.gov (United States)

    Ringeling, Arthur

    2015-01-01

    Both in Public Administration and in practice, there is a loss of the concept of public. A view became dominant in which markets were superior to governments and public to private. Not only did the esteem of the public sphere diminish, but also its significance in our reasoning and teaching. It became less clear what the public sphere stood for.…

  12. Schools of Excellence and Equity? Using Equity Audits as a Tool to Expose a Flawed System of Recognition

    Science.gov (United States)

    Brown, Kathleen M.

    2010-01-01

    The purpose of this article is to demonstrate how equity audits can be used as a tool to expose disparate achievement in schools that, on the surface and to the public, appear quite similar. To that end, the researcher probed beyond surface-level performance composite scores into deeper, more hidden data associated with state-recognized…

  13. Climate Change and Public Health.

    Science.gov (United States)

    Ciesielski, Timothy

    2017-05-01

    It is clear that the public health community is concerned about the human health impacts of climate change, but are we inadvertently underestimating the scope of the problem and obfuscating potentially useful interventions by using a narrow intellectual frame in our discussions with policy makers? If we take a more holistic approach, we see that the public health impacts of climate change are only one subset of the enormous public health impacts of fossil fuel burning. This broader perspective can provide a more accurate and comprehensive assessment that is more useful for decision making in public policy settings.

  14. Public relations as public information

    Energy Technology Data Exchange (ETDEWEB)

    Coninx, C.

    1983-01-01

    To the man in the street, the topic of nuclear energy on the one hand is a highly emotional subject incorporating dangers hard to assess. However, on the other hand, there is in most cases little inclination to concern oneself with problems of energy economy. Public relations activities therefore frequently must motivate their adresses to accept information before they can actually inform. In this connection, the informing party must appear trustworthy and avoid that a teacher : pupil relationship is created. In addition, the changes in the socio-political environment must be taken into account. Within the industries and organizations engaged in the nuclear field there is the problem that the effects and the impact of public relations work can hardly be gaged by individually, which greatly hampers quantification of the work actually done.

  15. Public relations

    International Nuclear Information System (INIS)

    1998-01-01

    The Nuclear Regulatory Authority of the Slovak Republic (NRA SR) laid the foundation of a policy of keeping the public informed about the activities and the safety of nuclear installations in the SR already in its origins by opening the NRA Information Centre. The NRA SR issues the Bulletin on NRA SR for domestic and foreign use, the bilingual Annual report on NRA activities for domestic and foreign public - detailed report for the specialists and a version for the Slovak Republic state authorities. On the occasion of the anniversary of the IAEA a special publication on the IAEA was prepared. Forty-nine contributions on NRA national and foreign activities were trans-missed to the Press Agency of the SR (TASR) over the course of 1997. In the journal Safety of Nuclear Energy the column 'Information' periodically carries the briefs on NRA activities. Four essential articles on NRA mission and responsibility in the are of peaceful uses of atomic energy were published in the Newsletter of the Slovak Information Agency (SIA). Contributions on NRA activities and international co-operation are periodically put out in the 'Slovenske elektrarne' Newsletter, the Slovak Nuclear Society Bulletin. Report on the Safety of NPPs in the Slovak Republic is annually published in the Journal European Nuclear Society - Nuclear Europe Worldscan. Some articles on NRA activities were published in the world information agency NucNet. The NRA issued in 1997 four editions of the internal Bulletin on the NRA's national and foreign activities and personnel. Three press conferences were held and six events were arranged in radio broadcasting in 1997

  16. Public meetings

    CERN Multimedia

    Staff Association

    2014-01-01

      Public meetings : Come and talk about your future employment conditions !   The Staff Association will come and present the results of our survey on the 2015 five-yearly review. Following the survey, the topics discussed, will be contract policy, recognition of merit (MARS), working time arrangements and family policy. After each meeting and around a cup of coffee or tea you will be able to continue the discussions. Do not hesitate to join us, the five-yearly review, it is with YOU!

  17. Public meetings

    CERN Multimedia

    Staff Association

    2014-01-01

      MARS 2015 FIVE YEARLY REVIEW CONTRACT POLICY PENSION FUND GENERAL INFORMATION   COME AND BE INFORMED! PUBLIC MEETINGS Friday 3rd October at 10 am Amphi BE, 864-1-D02 Prévessin Friday 3rd October at 2 pm Salle du Conseil / Council Chamber, 503-1-001 (in English) Meyrin Monday 6th October at 10 am Kjell Johnsen Auditorium, 30-7-018 Meyrin Monday 6th October at 2 pm Salle du Conseil / Council Chamber, 503-1-001 Meyrin  

  18. Post-exposure rabies prophylaxis in humans exposed to animals in Lublin province (Eastern Poland) in 2012-2015 - A retrospective study.

    Science.gov (United States)

    Krzowska-Firych, Joanna; Tomasiewicz, Krzysztof; Kozøowska, Agata

    2017-06-03

    Rabies continues to be one of the most important viral diseases and remains a significant threat to public health across the globe. The post-exposure prophylaxis in humans can effectively prevent death after exposure to a potentially infected animal. In Poland, recommendations for rabies PEP followed the national guidelines which recommend that people should receive PEP when bitten by an animal suspected to be infected by rabies. PEP in humans includes cleansing and disinfecting the wound or point of contact, and administering anti-rabies immunization. Rabies vaccine should be given for contacts of category II and category III exposures. RIG should be given for category III contact. The vaccination schedule includes 5 doses given within a 30 day period (the Essen regimen). The aim of our study was to determine the frequency of post-exposure prophylaxis among patients exposed to animals and also to assess the animal species suspected as a source of rabies exposure. We have retrospectively analyzed medical records from the years 2012-2015 of all adult patients who were exposed to animals and consulted at the Dispensary of Rabies Prophylaxis in the Department of Infectious Diseases at the Medical University in Lublin, Poland. All consulted patients were asked to give an informed consent in case of decision to use collected data for future research work. Ethical approval was obtained from the Ethics Committee of the Medical University of Lublin, Poland, and all patients included in this study gave an informed consent during consultation after the exposure to animals. During the studied 4-year period, 511 persons exposed to animals were consulted and prophylactic procedure consisting of active immunization were applied in 54.2% of the total consulted. Dogs and cats were the most common animal species suspected as the source of the rabies exposure. Anti-rabies prophylaxis was applied in 45.8% of all vaccinated patients exposed to dogs, and in 24.2% exposed to cats. All

  19. A survey on the public perception of CCS in France

    International Nuclear Information System (INIS)

    Minh, Ha-Duong; Campos, A.S.; Nadai, A.

    2007-12-01

    An awareness and opinion survey on Carbon Capture and Storage was conducted on a representative sample of French aged 15 years and above. About 6% of respondents were able to provide a satisfying definition of the technology. The key question about 'approval of or opposition to' the use of CCS in France was asked twice, first after presenting the technology, then after exposing the potential adverse consequences. Approval rates, 59% and 38%, show that there is no a priori rejection of the technology, but public trust needs to be build. The sample was split in two to test for a semantic effect: questioning one half about 'Stockage' (English: storage), the other about 'Sequestration'. Manipulating the vocabulary had no statistically significant effect on approval rates. Stockage is more meaningful, but does not convey the idea of permanent monitoring. (authors)

  20. [A survey of occupational health among polyether-exposed workers].

    Science.gov (United States)

    Fu, Xu-ying; Yu, Bin; Zhang, Chun-ping; Zheng, Guan-hua; Bai, Lan; Zhang, Pan-pan

    2013-06-01

    To investigate the occupational health of the workers simultaneously exposed to acrylonitrile, epoxyethane, epoxypropane, and styrene. A questionnaire survey was conducted in 70 front-line workers simultaneously exposed to acrylonitrile, epoxyethane, epoxypropane, and styrene (exposure group) and 50 managers (control group) in a polyether manufacturer; in addition, air monitoring at workplace and occupational health examination were also performed. The obtained data were analyzed. The female workers in exposure group and the spouses of male workers in exposure group had significantly higher spontaneous abortion rates than their counterparts in control group (P polyether-exposed working years had significantly higher mean levels of DNA damage than the control group (P polyether-exposed working years and those with not less than 20 polyether-exposed working years had significantly higher mean micronucleus rates than the control group (P polyether-exposed working years (P > 0.05); the workers with not less than 5 and less than 20 polyether-exposed working years and workers with not less than 20 polyether-exposed working years had significantly higher mean micronucleus rates than those with less than 5 polyether-exposed working years (P polyether manufacturer.

  1. Going beyond the most exposed people in a dose assessment

    Energy Technology Data Exchange (ETDEWEB)

    Hjerpe, Thomas; Broed, Robert [Facilia AB, Gustavslundsvaegen 151C, SE-167 51 Bromma (Sweden); Ikonen, Ari T.K. [Environmental Research and Assessment, EnviroCase, Ltd., Hallituskatu 1 D 4, FI-28 100 Pori (Finland)

    2014-07-01

    The dose assessment in a long-term radiation safety assessment often focus on assessing dose of a representative person to be used for determining compliance with a radiation dose constraint. This representative person is often assumed to receive a dose that is representative of the most exposed people, i.e., the more highly exposed individuals in the population. This is not always sufficient, the Finnish regulations for disposal of nuclear waste has radiation dose constraint to the most exposed people as well as for larger groups of exposed people. This work presents the methodology to assessing dose of a representative person for a larger group of exposed people as applied by Posiva in the TURVA-2012 safety case for the spent nuclear fuel disposal at Olkiluoto. In addition, annual doses from the set of biosphere calculation cases analysed in TURVA-2012 are presented and discussed. Special focus is given on explaining the differences in exposure levels and exposure routes between the estimated annual doses to representative persons for most exposed people and a larger exposed group. The results show that the annual doses to a larger group of people ranges from one to three orders of magnitude below the annual doses to the most exposed people. Furthermore, the exposure route related to food ingestion is less significant for the larger group of people compared to the most exposed people and that the exposure route related to water ingestion shows the opposite behaviour. (authors)

  2. Managing Public Accountability : How Public Managers Manage Public Accountability

    NARCIS (Netherlands)

    Schillemans, Thomas

    2015-01-01

    Accountability is of growing importance in contemporary governance. The academic literature on public accountability is fraught with concerned analyses, suggesting that accountability is a problematic issue for public managers. This article investigates how public managers experience accountability

  3. Potential Exposures to Australian Bat Lyssavirus Notified in Queensland, Australia, 2009-2014.

    Directory of Open Access Journals (Sweden)

    Damin Si

    2016-12-01

    Full Text Available Australian bat lyssavirus (ABLV belongs to the genus Lyssavirus which also includes classic rabies virus and the European lyssaviruses. To date, the only three known human ABLV cases, all fatal, have been reported from Queensland, Australia. ABLV is widely distributed in Australian bats, and any bite or scratch from an Australian bat is considered a potential exposure to ABLV.Potential exposure to ABLV has been a notifiable condition in Queensland since 2005. We analysed notification data for potential exposures occurring between 2009 and 2014. There were 1,515 potential exposures to ABLV notified in Queensland, with an average annual notification rate of 5.6 per 100,000 population per year. The majority of notified individuals (96% were potentially exposed to ABLV via bats, with a small number of cases potentially exposed via two ABLV infected horses and an ABLV infected human. The most common routes of potential exposure were through bat scratches (47% or bites (37%, with less common routes being mucous membrane/broken skin exposure to bat saliva/brain tissue (2.2%. Intentional handling of bats by the general public was the major cause of potential exposures (56% of notifications. Examples of these potential exposures included people attempting to rescue bats caught in barbed wire fences/fruit tree netting, or attempting to remove bats from a home. Following potential exposures, 1,399 cases (92% were recorded as having appropriate post-exposure prophylaxis (PEP as defined in national guidelines, with the remainder having documentation of refusal or incomplete PEP. Up to a quarter of notifications occurred after two days from the potential exposure, but with some delays being more than three weeks. Of 393 bats available for testing during the reporting period, 20 (5.1% had ABLV detected, including four species of megabats (all flying foxes and one species of microbats (yellow-bellied sheathtail bat.Public health strategies should address the

  4. Potential Exposures to Australian Bat Lyssavirus Notified in Queensland, Australia, 2009−2014

    Science.gov (United States)

    Si, Damin; Marquess, John; Donnan, Ellen; Harrower, Bruce; McCall, Bradley; Bennett, Sonya; Lambert, Stephen

    2016-01-01

    Background Australian bat lyssavirus (ABLV) belongs to the genus Lyssavirus which also includes classic rabies virus and the European lyssaviruses. To date, the only three known human ABLV cases, all fatal, have been reported from Queensland, Australia. ABLV is widely distributed in Australian bats, and any bite or scratch from an Australian bat is considered a potential exposure to ABLV. Methodology/Principal Findings Potential exposure to ABLV has been a notifiable condition in Queensland since 2005. We analysed notification data for potential exposures occurring between 2009 and 2014. There were 1,515 potential exposures to ABLV notified in Queensland, with an average annual notification rate of 5.6 per 100,000 population per year. The majority of notified individuals (96%) were potentially exposed to ABLV via bats, with a small number of cases potentially exposed via two ABLV infected horses and an ABLV infected human. The most common routes of potential exposure were through bat scratches (47%) or bites (37%), with less common routes being mucous membrane/broken skin exposure to bat saliva/brain tissue (2.2%). Intentional handling of bats by the general public was the major cause of potential exposures (56% of notifications). Examples of these potential exposures included people attempting to rescue bats caught in barbed wire fences/fruit tree netting, or attempting to remove bats from a home. Following potential exposures, 1,399 cases (92%) were recorded as having appropriate post-exposure prophylaxis (PEP) as defined in national guidelines, with the remainder having documentation of refusal or incomplete PEP. Up to a quarter of notifications occurred after two days from the potential exposure, but with some delays being more than three weeks. Of 393 bats available for testing during the reporting period, 20 (5.1%) had ABLV detected, including four species of megabats (all flying foxes) and one species of microbats (yellow-bellied sheathtail bat). Conclusions

  5. Philanthropic Support for Public Education in the Southwestern Region: An Assay of Philanthropy's Potential To Impact Comprehensive School Reform in Arkansas, Louisiana, New Mexico, Oklahoma, and Texas. Environmental Scanning Brief.

    Science.gov (United States)

    Born, Laurie; Wilson, Dave

    This report examines the relationship between philanthropy and public schools in Arkansas, Louisiana, New Mexico, Oklahoma, and Texas served by the Southwest Educational Development Laboratory (SEDL). While begun as a project to build understanding and to support institutional planning, this report speaks also to local school leaders, the…

  6. Public relations

    International Nuclear Information System (INIS)

    1997-01-01

    Nuclear Regulatory Authority of the Slovak Republic (NRA SR) started building up a broad information publicity conception resulting in NRA SR Information Centre establishment in 1995. The Centre provides information on the NRA SR activities. The Authority's speaker provides information about NRA SR domestic and foreign activities for TASR, newspapers, Slovak radio and television. Information on nuclear energy facilities situation is given to state authorities, organizations as well as to domestic and foreign mass-media on request. 41 press releases, 3 radio interviews and 5 television records providing information on some important NRA SR events was worked out in 1996. 4 basic NRA SR document have been presented by the Slovak Information Agency, consequently 3 press-conferences were held. Concerning some less frequent communication activities, NRA SR can present the NRA SR annual report in three versions (for the Slovak Government, for public and detailed report for experts). NRA SR and State Authority for Nuclear Safety of the Czech Republic issue together Nuclear Energy Safety News every two months. NRA SR activities Bulletin started issuing in 1996 3 to 4 volumes per year. Newspaper, radio and television news monitoring is performed for Bratislava and Trnava offices providing interesting papers or important events records and photos of NRA SR visits. Practical experience of the information activities performance in connection with the Authority mission and liability was obtained last year. Methodical and organizational guidelines to adjust the state regulatory authority activities in this field have been prepared

  7. Scientific colloquium on medical supervision of workers exposed to ionizing and non ionizing radiations

    International Nuclear Information System (INIS)

    1975-01-01

    The general principles of medical surveillance for workers exposed to ionizing radiation were defined in the Euratom Basic Standards in 1959. These principles, which are in accordance with the early IGRP publications, have been adopted by the national authorities and implemented without difficulty. However, because of the forthcoming publication of the revised Basic Standards- in accordance with recent IGRP recommendations, the Commission decided to organize a meeting of doctors responsible for the medical surveillance of workers exposed to ionizing radiation in order to disseminate as widely as possible the results of experience gained in the field of radiological protection and to pinpoint the practical difficulties which might arise when the principles were applied. The Commission also considered it important to inform doctors specializing in radiological protection about the principles to be followed by those responsible for the health protection of workers exposed to non-ionizing radiation, particularly microwaves and Laser beams. The complete text of each report in the original language is given in this volume

  8. Response of exposed bark and exposed lichen to an urban area

    Energy Technology Data Exchange (ETDEWEB)

    Cruz, A.M.J. [Polytechnic Institute of Coimbra, Oliveira do Hospital (Portugal). Oliveira do Hospital College of Technology and Management; Freitas, M.C.; Canha, N. [URSN, Sacavem (Portugal). Inst. Tecnologico e Nuclear (ITN); Verburg, T.G.; Wolterbeek, H.T. [Technical Univ. of Delft (Netherlands). Dept. of Radiation, Radionuclides and Reactors

    2011-07-01

    The aim of this study is to understand emission sources of chemical elements using biomonitoring as a tool. The selected lichen and bark were respectively Parmotrema bangii and Criptomeria japonica, sampled in the pollution-free atmosphere of Azores (Sao Miguel island), Portugal, and were exposed in the courtyards of 22 basic schools of Lisbon. The exposure was from January to May 2008 and from June to October 2008 (designated through the text as winter and summer respectively). The chemical element concentrations were determined by INAA. Conductivity of the lichen samples was measured. Factor analysis (MCTTFA) was applied to winter/summer bark/lichen exposed datasets. Arsenic emission sources, soil with anthropogenic contamination, a Se source, traffic, industry, and a sea contribution, were identified. In lichens, a physiological source based on the conductivity values was found. The spatial study showed contribution of sources to specific school positioning. Conductivity values were high in summer in locations as international Lisbon airport and downtown. Lisbon is spatially influenced by marine air mass transportation. It is concluded that one air sampler in Lisbon might be enough to define the emission sources under which they are influenced. (orig.)

  9. Ecophysiological tolerance of duckweeds exposed to copper

    Energy Technology Data Exchange (ETDEWEB)

    Kanoun-Boule, Myriam [Centre for Functional Ecology, Department of Botany, University of Coimbra, Coimbra 3000-456 (Portugal)], E-mail: mkb@ci.uc.pt; Vicente, Joaquim A.F.; Nabais, Cristina [Centre for Functional Ecology, Department of Botany, University of Coimbra, Coimbra 3000-456 (Portugal); Prasad, M.N.V. [Department of Plant Sciences, University of Hyderabad, Hyderabad 500046 (India); Freitas, Helena [Centre for Functional Ecology, Department of Botany, University of Coimbra, Coimbra 3000-456 (Portugal)

    2009-01-18

    Although essential for plants, copper can be toxic when present in supra-optimal concentrations. Metal polluted sites, due to their extreme conditions, can harbour tolerant species and/or ecotypes. In this work we aimed to compare the physiological responses to copper exposure and the uptake capacities of two species of duckweed, Lemna minor (Lm(EC1)) and Spirodela polyrrhiza (SP), from an abandoned uranium mine with an ecotype of L. minor (Lm(EC2)) from a non-contaminated pond. From the lowest Cu concentration exposure (25 {mu}M) to the highest (100 {mu}M), Lm(EC2) accumulated higher amounts of copper than Lm(EC1) and SP. Dose-response curves showed that Cu content accumulated by Lm(EC2) increases linearly with Cu treatment concentrations (r{sup 2} = 0.998) whereas quadratic models were more suitable for Lm(EC1) and SP (r{sup 2} = 0.999 and r{sup 2} = 0.998 for Lm(EC1) and SP, respectively). A significant concentration-dependent decline of chlorophyll a (chl a) and carotenoid occurred as a consequence of Cu exposure. These declines were significant for Lm(EC2) exposed to the lowest Cu concentration (25 {mu}M) whereas for Lm(EC1) and SP a significant decrease in chl a and carotenoids was observed only at 50 and 100 {mu}M-Cu. Electric conductivity (EC) and malondialdehyde (MDA) content increased after Cu exposure, indicating oxidative stress. Significant increase of EC was observed in Lm(EC2) for all Cu concentrations whereas the increase for Lm(EC1) and SP became significant only after an exposure to 50 {mu}M-Cu. On the contrary, for Lm(EC1), SP, and Lm(EC2), MDA content significantly increased even at the lowest concentration. Protein content and catalase (CAT) activity showed a decrease with an increase in Cu concentration. For the species Lm(EC1) and SP, a significant effect of copper on CAT activity was observed only at the highest concentration (100 {mu}M-Cu) whereas, for Lm(EC2), this effect started to be significant after an exposure to 50 {mu

  10. Ecophysiological tolerance of duckweeds exposed to copper

    International Nuclear Information System (INIS)

    Kanoun-Boule, Myriam; Vicente, Joaquim A.F.; Nabais, Cristina; Prasad, M.N.V.; Freitas, Helena

    2009-01-01

    Although essential for plants, copper can be toxic when present in supra-optimal concentrations. Metal polluted sites, due to their extreme conditions, can harbour tolerant species and/or ecotypes. In this work we aimed to compare the physiological responses to copper exposure and the uptake capacities of two species of duckweed, Lemna minor (Lm(EC1)) and Spirodela polyrrhiza (SP), from an abandoned uranium mine with an ecotype of L. minor (Lm(EC2)) from a non-contaminated pond. From the lowest Cu concentration exposure (25 μM) to the highest (100 μM), Lm(EC2) accumulated higher amounts of copper than Lm(EC1) and SP. Dose-response curves showed that Cu content accumulated by Lm(EC2) increases linearly with Cu treatment concentrations (r 2 = 0.998) whereas quadratic models were more suitable for Lm(EC1) and SP (r 2 = 0.999 and r 2 = 0.998 for Lm(EC1) and SP, respectively). A significant concentration-dependent decline of chlorophyll a (chl a) and carotenoid occurred as a consequence of Cu exposure. These declines were significant for Lm(EC2) exposed to the lowest Cu concentration (25 μM) whereas for Lm(EC1) and SP a significant decrease in chl a and carotenoids was observed only at 50 and 100 μM-Cu. Electric conductivity (EC) and malondialdehyde (MDA) content increased after Cu exposure, indicating oxidative stress. Significant increase of EC was observed in Lm(EC2) for all Cu concentrations whereas the increase for Lm(EC1) and SP became significant only after an exposure to 50 μM-Cu. On the contrary, for Lm(EC1), SP, and Lm(EC2), MDA content significantly increased even at the lowest concentration. Protein content and catalase (CAT) activity showed a decrease with an increase in Cu concentration. For the species Lm(EC1) and SP, a significant effect of copper on CAT activity was observed only at the highest concentration (100 μM-Cu) whereas, for Lm(EC2), this effect started to be significant after an exposure to 50 μM-Cu. Superoxide dismutase (SOD) activity

  11. Prediction of acid generation potential

    International Nuclear Information System (INIS)

    Nalbandyan, V.B.

    1992-01-01

    This paper discusses acid rock drainage (ARD), a term used to describe leachate, seepage, or drainage that has been affected by the natural oxidation of sulfide minerals contained in rock which is exposed